Radioprotective effects of hawthorn fruit extract against gamma irradiation in mouse bone marrow cells

International Nuclear Information System (INIS)

Hosseinimehr, S.J.; Azadbakht, M.; Mousavi, S.M.; Mahmoudzadeh, A.; Akhlaghpoor, S.

2007-01-01

The radioprotective effect of hawthorn (Crataegus microphylla) fruit extract against genotoxicity induced by gamma irradiation has been investigated in mouse bone marrow cells. A single intraperitoneal (ip) administration of hawthorn extract at doses of 25, 50, 100 and 200 mg/kg 1 h prior to gamma irradiation (2 Gy) reduced the frequencies of micronucleated polychromatic erythrocytes (MnPCEs). All four doses of hawthorn extract significantly reduced the frequencies of MnPCEs and increased the PCE/PCE+NCE ratio (polychromatic erythrocyte/polychromatic erythrocyte+normochromatic erythrocyte) in mice bone marrow compared with the non drug-treated irradiated control (p<0.02-0.00001). The maximum reduction in MnPCEs was observed in mice treated with extract at a dose of 200 mg/kg. Administration of amifostine at dose 100 mg/kg and hawthorn at dose 200 mg/kg reduced the frequency of MnPCE almost 4.8 and 5.7 fold; respectively, after being exposed to 2 Gy of gamma rays, compare with the irradiated control group. Crataegus extract exhibited concentration-dependent activity on 1, 1-diphenyl 2-picrylhydrazyl free radical showing that Crataegus contained high amounts of phenolic compounds and the high performance liquid chromatography (HPLC) analysis determined that it contained chlorogenic acid, epicatechin and hyperoside. It appeared that hawthorn extract with antioxidant activity reduced the genotoxicity induced by gamma irradiation in bone marrow cells. (author)

Effect of Hawthorn on Drosophila Melanogaster Antioxidant-Related ...

African Journals Online (AJOL)

Results: The results indicate that hawthorn extract prolonged the life span of Drosophila, with 50 % survival time of 0.8 ... Drosophila's aging gene is highly similar to humans [4,5]. ..... reduces lipid peroxidation in senescence-accelerated mice .

Antitumoral, antioxidant, and antimelanogenesis potencies of Hawthorn, a potential natural agent in the treatment of melanoma.

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Mustapha, Nadia; Mokdad-Bzéouich, Imèn; Maatouk, Mouna; Ghedira, Kamel; Hennebelle, Thierry; Chekir-Ghedira, Leila

2016-06-01

The lack of an efficient agent that does not have the disadvantage of low activity (kojic acid), high cytotoxicity, and mutagenicity (hydroquinone), poor skin penetration (arbutin), or low stability in formulation (glabridin) led us to continue our research on new antipigmentation/skin-lightening agents. Therefore, research of natural products that can modulate the metabolism of pigmentation is of great interest. Otherwise, malignant melanoma is one of the most aggressive forms of skin cancer, with high metastatic potential, and currently, there is no effective chemotherapy against invasive melanoma. Therefore, it is necessary to develop new drugs with potent activity and weak side effects against melanoma. The in-vitro anticancer effect of hawthorn was analyzed against B16F10 melanoma cells using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. The effect of isolated compounds from hawthorn on melanogenesis in B16F10 melanoma cells was investigated by measuring the amounts of melanin and tyrosinase spectrophotometrically at 475 nm. Balb/c mice models inoculated with B16F10 mouse tumor cells were used to evaluate the in-vivo antitumoral potential of hawthorn by assessing its effect on the growth of transplanted tumors. The antioxidant potential of tested samples was evaluated in B16F10 and primary human keratinocyte cells using a cellular antioxidant activity assay. Hawthorn tested samples inhibited effectively the growth of melanoma cells in vitro. Furthermore, it appears that tested samples from hawthorn reduced melanogenesis by inhibiting the tyrosinase activity of B16F10 cells in a dose-dependent manner. In-vivo studies showed that hawthorn total oligomer flavonoids extract treatment at a dose of 150 mg/kg body weight for 21 days in implanted tumor mice resulted in significant inhibition of the tumor growth volume and weight. In addition, tested samples showed significant cellular antioxidant capacity against the reactive oxygen species

Resveratrol combined with total flavones of hawthorn alleviate the endothelial cells injury after coronary bypass graft surgery.

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Zhu, Ying; Feng, Bing; He, Songmin; Su, Zuqing; Zheng, Guangjuan

2018-02-01

To explore the preventive and therapeutic effects of Resveratrol combined with total flavones of hawthorn, compatibility of traditional Chinese medicines, on the endothelial cells injury after artery bypass graft surgery. The animal model of coronary artery bypass grafting (CABG) was prepared by transplanting a segment of autologous jugular vein onto the transected common carotid artery in rabbits. After CABG surgery, the rabbits were administrated with saline (model group), aspirin (Aspirin group), resveratrol (Res group), total flavones of hawthorn (Haw group) and resveratrol combined with total flavones of hawthorn (Res+Haw group) once a day for eight weeks, respectively. Eight weeks later, the grafting arteries from all group were obtained for the pathomorphism observation, peripheral blood was collected to detect circulating endothelial cells (CECs) by flow cytometry. And the concentration of albumen and mRNA of ICAM-1 in the serum were measured by western blot and quantitative real-time polymerase chain reaction, respectively. Compared with the model group, the level of CECs density and the expressions of albumen and mRNA of ICAM-1 were significantly decreased in the aspirin,resveratrol,total flavones of hawthorn and resveratrol combined with total flavones of hawthorn groups (P Resveratrol combined with total flavones of hawthorn could protect the endothelial cells after coronary artery bypass graft. Copyright © 2018 Elsevier GmbH. All rights reserved.

Stunted sexuality in hawthorne's the blithedale romance Stunted sexuality in hawthorne's the blithedale romance

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Arnold Gordenstein

2008-04-01

Full Text Available By now a commonplace of Blithedale Romance criticism is that Coverdale is a voyeur. But hardly anyone has related coverdale's voyeurism to the larger psychological pattern that includes voyeurism and these to its central themes. Otto Fenichel couples voyeurism and toucheurism and defines them as "scoptophilia, the sexualization of the sensations of looking... analogous to touch eroticism." 1 Doubly restricted by Victorian morality as well as by his American Puritan heritage, Hawthorne indicated that the motivations that drew people to and that characterized their relationships at Blithedale were, in part, sexual. Since he could not directly describe this sexuality he used sight and touch images to convey the kind of attraction he had in mind. By now a commonplace of Blithedale Romance criticism is that Coverdale is a voyeur. But hardly anyone has related coverdale's voyeurism to the larger psychological pattern that includes voyeurism and these to its central themes. Otto Fenichel couples voyeurism and toucheurism and defines them as "scoptophilia, the sexualization of the sensations of looking... analogous to touch eroticism." 1 Doubly restricted by Victorian morality as well as by his American Puritan heritage, Hawthorne indicated that the motivations that drew people to and that characterized their relationships at Blithedale were, in part, sexual. Since he could not directly describe this sexuality he used sight and touch images to convey the kind of attraction he had in mind.

Polyphenolic Profile and Biological Activity of Chinese Hawthorn (Crataegus pinnatifida BUNGE Fruits

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Tunde Jurikova

2012-12-01

Full Text Available Chinese hawthorn (Crataegus pinnatifida Bge. fruits are rich in polyphenols (e.g., epicatechin, procyanidin B2, procyanidin B5, procyanidin C1, hyperoside, isoquercitrin and chlorogenic acid—active compounds that exert beneficial effects. This review summarizes all information available on polyphenolic content and methods for their quantification in Chinese hawthorn berries and the relationships between individual polyphenolic compounds as well. The influence of species or cultivars, the locality of cultivation, the stage of maturity, and extract preparation conditions on the polyphenolic content were discussed as well. Currently, only fruits of C. pinnatifida and C. pinnatifida var. major are included in the Chinese Pharmacopoeia. Recent trials have demonstrated the efficacy of Chinese hawthorn fruit in lowering blood cholesterol and the risk of cardiovascular diseases. The fruit has also demonstrated anti-inflammatory and anti-tumour activities. This review deals mainly with the biological activity of the fruit related to its antioxidant properties.

Jhumpa Lahiri's Unaccustomed Earth and the Reading of Nathaniel Hawthorne

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Israa Hashim Taher

2016-10-01

Full Text Available Born in England, to Bengali parents, and raised in America, Jhumpa Lahiri (1967 has been variously labeled as Indian-American, post-modern, post-colonial, and Indian writer. Naming Lahiri has been a long and intricate process. However, the identity she chooses for herself is something different. She wants herself to be simply recognized as an American writer. In her first novel, The Namesake (2003, the  protagonist, reflecting the dilemma of his creator, suffers the confusing experience of having an appropriate name.  Lahiri  resorts to Russian literature to establish an identity for her protagonist. In her second collection of short stories,  Unaccustomed Earth (2008, Lahiri uses the American writer Nathaniel Hawthorne not just to suggest the title, and epigraph for the collection, but more importantly to "establish her belonging in an American literary canon," as Ambreen Hai suggests in "Re-Rooting Families: The Alter/Natal as the Central Dynamic of Jhumpa Lahiri's Unaccustomed Earth." I want to push this argument further by suggesting that Lahiri attempts to gain her formal entry into the main stream American literature by re-writing Hawthorne's The Scarlet Letter (1850in reverse order in "Hema and Kaushik", the second part of  Unaccustomed Earth. Keywords: Lahiri, Hawthorne, India, Scarlet Letter, identity, America

The Hawthorne effect in direct observation research with physicians and patients.

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Goodwin, Meredith A; Stange, Kurt C; Zyzanski, Stephen J; Crabtree, Benjamin F; Borawski, Elaine A; Flocke, Susan A

2017-12-01

This study examines the degree to which a "Hawthorne effect" alters outpatient-visit content. Trained research nurses directly observed 4454 visits to 138 family physicians. Multiple data sources were used to examine the Hawthorne effect including differences in medical record documentation for observed visits and the prior visit by the same patient, time use during visits on the first versus the second observation day of each physician, and report by the patient, physician, and observer of the effect of observation. Visits on the first versus the second observation day were longer by an average of 1 minute (P effect of the observer on the interaction was reported by 74% of patients and 55% of physicians. Most of those that reported an affect indicated it was slight. Patients with non-White race, lower-educational level, and poorer health were more likely to report being affected by the observer. In a study that was designed to minimize the Hawthorne effect, the presence of an observer had little effect on most patient-physician visits but appeared to at least slightly effect a subgroup of vulnerable patients. © 2017 John Wiley & Sons, Ltd.

Organic acids, sugars, vitamin C content and some pomological characteristics of eleven hawthorn species (Crataegus spp.) from Turkey.

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Gundogdu, Muttalip; Ozrenk, Koray; Ercisli, Sezai; Kan, Tuncay; Kodad, Ossama; Hegedus, Attila

2014-05-30

The Hawthorn (Crateagus sp.) mostly occurs around the temperate region of the world with a high number of species, producing a fruit with numerous beneficial effects for human health. The aim of the study was to determine organic acid and sugar contents in the fruit of a number of hawthorn species grown in Erzincan province of Turkey. Citric acid was the predominant organic acid in all hawthorn species and C. pseudoheterophylla had the highest citric acid content (23.688 g/100 g). There were not statistically significant differences among hawthorn species (except C. atrosanguinea Pojark) in terms of fumaric acid content. C.pontica C.Koch had a higher content of vitamin C (9.418 mg/100 g) compared to other species. Fructose was the predominant sugar component in all species and C. monogyna subsp. monogyna Joiq had the highest fructose content (18.378 g/100 g). The high fruit quality of the studied species indicates the importance of this fruit in human nutrition as a natural source. The study revealed that there were differences in terms of fruit characteristics among hawthorn species and thus better quality hawthorn genotypes can be selected within the species. Hence, this study is considered to be a valuable reference for forthcoming studies. The high fruit quality of the studied species indicates the importance of this fruit in human nutrition as a natural source.

Effect of SiO2 nanoparticles on drought resistance in hawthorn seedlings

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Ashkavand Peyman

2015-12-01

Full Text Available Drought is a significant factor limiting crop production in arid regions while hawthorns (Crataegus sp. are an important component of such region’s forests. Therefore, treatments that increase hawthorn drought resistance may also increase transplanting success. Thus, the physiological and biochemical responses of hawthorn seedlings to a factorial combination of different concentrations of silica nanoparticles (SNPs at 0, 10, 50 and 100 mg L−1 and three soil moisture treatments (without stress, moderate stress and severe stress were investigated. Seedlings were irrigated with one of the four concentrations of SNPs for 45 days before exposing them to drought stress. Photosynthesis parameters, malondialdehyde (MDA, relative water content (RWC, membrane electrolyte leakage (ELI as well as chlorophyll, carotenoid, carbohydrate and proline content were determined. At the end of the experiment, positive effects by SNP pre-treatment on physiological indexes were observed during drought stress. Under drought conditions, the effect of SNPs on photosynthetic rate and stomatal conductance was evident. Although the SNPs increased plant biomass, xylem water potential and MDA content, especially under drought conditions, RWC and ELI were not affected by the SNP pre-treatments. Seedlings pre-treated with SNPs had a decreased carbohydrate and proline content under all water regimes, but especially so under drought. Total chlorophyll content and carotenoid content did not change among the treatments. Generally, the findings imply that SNPs play a positive role in maintaining critical physiological and biochemical functions in hawthorn seedlings under drought stress conditions. However, more studies are needed before the physiological and biochemical basis of induced drought resistance can be determined.

Organic acids, sugars, vitamin C content and some pomological characteristics of eleven hawthorn species (Crataegus spp. from Turkey

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Muttalip Gundogdu

2014-01-01

Full Text Available BACKGROUND: The Hawthorn (Crateagus sp. mostly occurs around the temperate region of the world with a high number of species, producing a fruit with numerous beneficial effects for human health. The aim of the study was to determine organic acid and sugar contents in the fruit of a number of hawthorn species grown in Erzincan province of Turkey. RESULTS: Citric acid was the predominant organic acid in all hawthorn species and C. pseudoheterophylla had the highest citric acid content (23.688 g/100 g. There were not statistically significant differences among hawthorn species (except C. atrosanguinea Pojark in terms of fumaric acid content. C. pontica C.Koch had a higher content of vitamin C (9.418 mg/100 g compared to other species. Fructose was the predominant sugar component in all species and C. monogyna subsp. monogyna Joiq had the highest fructose content (18.378 g/100 g. CONCLUSIONS: The high fruit quality of the studied species indicates the importance of this fruit in human nutrition as a natural source. The study revealed that there were differences in terms of fruit characteristics among hawthorn species and thus better quality hawthorn genotypes can be selected within the species. Hence, this study is considered to be a valuable reference for forthcoming studies. The high fruit quality of the studied species indicates the importance of this fruit in human nutrition as a natural source.

Establishment and growth of hawthorn in floodplains in the Netherlands

NARCIS (Netherlands)

Decuyper, M.; Cornelissen, P.; Sass, U.G.W.

2014-01-01

Dendrochronology was used to assess the influence of soil conditions, elevation and related inundation, climate fluctuations and vegetation cover on the establishment and growth of hawthorn in non-grazed river floodplains. Presence of forest influences the discharge capacity of the floodplain,

Pictorial Cross-Currents between Hawthorne and Atwood: Negotiating with the Dead

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Patricia Simonson

2015-06-01

Full Text Available This paper analyzes the way in which a contemporary Canadian novelist, Margaret Atwood, uses the work of a canonical nineteenth-century American novelist, Nathaniel Hawthorne, to define her own position as a writer, while at the same time criticizing and transforming her precursor’s reflection on the writer’s task. I identify this process in Atwood’s 1996 novel, Alias Grace: it takes the form of a rewriting of Hawthorne’s most famous novel, The Scarlet Letter. An important connection between the two writers is their common use of visual art to pose, and potentially to resolve, the problems they encounter as artists in a hostile environment. Este artículo analiza cómo una novelista canadiense contemporánea, Margaret Atwood, utiliza la obra de un novelista norteamericano del siglo diecinueve, Nathaniel Hawthorne, para definir su propia posición como escritora, y también para criticar y transformar la reflexión de su predecesor. Este proceso se da en una novela de 1996, Alias Grace, en forma de una reescritura de la novela más famosa de Hawthorne, La letra escarlata. Una conexión importante entre los dos escritores es su uso del arte visual para plantear, y posiblemente resolver, los problemas que encuentran como artistas en un entorno hostil.

Mozart, Hawthorne, and Mario Savio: Aesthetic Power and Political Complicity.

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Herbert, T. Walter

1995-01-01

Discusses the false dichotomy pitting aesthetic power against political complicity in literary criticism. Considers the sexual politics of the household of Nathaniel Hawthorne in light of this opposition. Suggests how literary works keep warring voices and inner conflicts alive and at odds. (HB)

Is the Hawthorne Effect in Educational Experiments a Chimera?

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Bauernfeind, Robert H.; Olson, Carl J.

1973-01-01

Reports on an experimental study designed to investigate the relationship between two factors commonly regarded as components of the Hawthorne Effect on pupil performance and on intellectual task. These factors are (1) direct cue, or awareness of experimentation, as represented by an announcement that pupils were the subjects of an experiment; and…

Transcriptome analysis and ultrastructure observation reveal that hawthorn fruit softening is due to cellulose/hemicellulose degradation

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Jiayu Xu

2016-10-01

Full Text Available Softening, a common phenomenon in many fruits, is a well coordinated and genetically determined process. However, the process of flesh softening during ripening has rarely been described in hawthorn. In this study, we found that ‘Ruanrou Shanlihong 3 Hao’ fruits became softer during ripening, whereas ‘Qiu JinXing’ fruits remained hard. At late developmental stages, the firmness of ‘Ruanrou Shanlihong 3 Hao’ fruits rapidly declined, and that of ‘Qiu JinXing’ fruits remained essentially unchanged. According to transmission electron microscopy (TEM, the middle lamella of ‘Qiu JinXing’ and ‘Ruanrou Shanlihong 3 Hao’ fruit flesh was largely degraded as the fruits matured. Microfilaments in ‘Qiu JinXing’ flesh were arranged close together and were deep in color, whereas those in ‘Ruanrou Shanlihong 3 Hao’ fruit flesh were arranged loosely, partially degraded and light in color. RNA-Seq analysis yielded approximately 46.72 Gb of clean data and 72,837 unigenes. Galactose metabolism and pentose and glucuronate interconversions are involved in cell wall metabolism, play an important role in hawthorn texture. We identified 85 unigenes related to the cell wall between hard- and soft-fleshed hawthorn fruits. Based on data analysis and real-time PCR, we suggest that β-GAL and PE4 have important functions in early fruit softening. The genes Ffase, Gns, α-GAL, PE63, XTH and CWP, which are involved in cell wall degradation, are responsible for the different textures of hawthorn fruits. Thus, we hypothesize that the different textures of ‘Qiu JinXing’ and ‘Ruanrou Shanlihong 3 Hao’ fruits at maturity mainly result from cellulose/hemicelluloses degradation rather than from lamella degradation. Overall, we propose that different types of hydrolytic enzymes in cells interact to degrade the cell wall, resulting in ultramicroscopic Structure changes in the cell wall and, consequently, fruit softening. These results provide

Natural Arsenic in the Miocene Hawthorn Group, Florida: Wide Ranging Implications for ASR, Phosphate Mining, Private Well

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Lazareva, O. V.; Pichler, T.

2004-12-01

In order to understand the mineralogical association and distribution of arsenic (As) in the Hawthorn Group we examined in detail the chemical and mineralogical composition of 370 samples that were collected from 16 cores in central Florida. In our study area the Hawthorn group consists primarily of a basal carbonate unit (the Arcadia Formation) and an upper siliciclastic unit (The Peace River Formation). The Peace River Formation contains appreciable amounts of phosphate and is currently being exploited for phosphate ore. Samples were taken for each Formation at intervals of 25ft. In addition to the interval samples we also took samples that contained visible pyrite crystals, iron oxides, green clays, phosphatic and organic material. These additional samples were collected because of their potential of high As concentrations. Arsenic concentrations were determined by hydride generation - atomic fluorescence spectrometry (HG-AFS) after digestion with aqua regia (3:1 HCl and HNO3). The elements Fe, Na, Al, Si, Mg, Ca, S, P, and K were measured on the same solutions by inductively coupled plasma optical emission spectrometry (ICP-OES). The identification of discrete minerals was aided by scanning electron microscopy (SEM) and chemical compositions were obtained by electron-probe microanalyses (EMPA). Our study indicates that the average As concentrations significantly change from 9.0 ppm in the Peace River Formation to 3.0 ppm in the Tampa Member of the Arcadia Formation. As concentrations for all Hawthorn samples vary from 0.07 to 68.98 ppm ( μ = 5.6, σ = 7.1). Our detailed mineralogical and geochemical study demonstrates that: (1) The As in the Hawthorn group varies from the formation to formation and is mostly concentrated in trace minerals, such as pyrite; (2) Concentrations of the As in pyrite crystals can vary drastically from a minimum of 0 ppm to a maximum of 8260 ppm; (3) Pyrite is an unevenly distributed throughout the Hawthorn Group; (4) Phosphate and

Naturally occurring arsenic in the Miocene Hawthorn Group, southwestern Florida: Potential implication for phosphate mining

International Nuclear Information System (INIS)

Lazareva, Olesya; Pichler, Thomas

2007-01-01

To understand the mineralogical association, concentration, and distribution of arsenic (As) in the Hawthorn Group, the chemical and mineralogical composition of 362 samples that were collected from 16 cores in southwestern Florida were examined in detail. In the study area, the Hawthorn Group consisted primarily of a basal carbonate unit (the Arcadia Formation) and an upper siliciclastic unit (The Peace River Formation). The Peace River Formation contains appreciable amounts of phosphate and is currently being exploited for phosphate ore. Samples were taken from cores of each formation at intervals of 7.5 m. In addition, to the interval samples, sections likely to have high As concentrations, such as zones with pyrite crystals, hydrous ferric oxides, green clays, and organic material, were collected and analyzed. Bulk As concentrations were determined by hydride generation-atomic fluorescence spectrometry (HG-AFS) after digestion with aqua regia (3:1 HCl and HNO 3 ). The elements Fe, Al, Si, Mg, Ca, S, and P were measured on the same solutions by inductively coupled plasma optical emission spectrometry (ICP-OES). The identification of discrete minerals was aided by scanning electron microscopy (SEM) and chemical compositions within the sample matrix and in individual minerals were obtained by electron-probe microanalysis (EMPA). This detailed mineralogical and geochemical study demonstrated that: (1) As in the Hawthorn Group varied from formation to formation and was mostly concentrated in trace minerals, such as pyrite; (2) average As concentrations significantly changed from 8.8 mg/kg (σ = 8.6 mg/kg) in the Peace River Formation to 3.0 mg/kg (σ = 3.7 mg/kg) in the Tampa Member of the Arcadia Formation. Arsenic concentrations for all Hawthorn samples varied from 0.1 to 69.0 mg/kg; (3) pyrite, with one exception, occurred as framboids and was unevenly distributed throughout the Hawthorn Group; (4) pyrite framboids were located inside a francolite (carbonate

The determination of hyperoside in the flower and leaf of hawthorn (Crataegus oxycantha and Crataegus monogyna by the spectrophotometric method

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Mihajlović Dušanka

2006-01-01

Full Text Available The flower and leaf of hawthorn contains many active components, used in the production of pharmaceutical preparations for cardiotonic, anti-hypertonic anti-hypotonic, artherosclerotic, anti-arithmic and anti-anemic groups. According to the ROTTE list (1996, 159 of 1800 pharmaceutical preparations contain components from hawthorn. Due to the remedial action of hyperoside and other flavonoids from hawthorn, their determination is important for the standardization of extract and preparation quality. The extraction of the flavonoids from a mixture of hawthorn (C. oxycantha and C. monogyna flower and leaf was carried out by percolation with 40% and 70% (v/v ethanol. In order to determine the content of total flavonoids calculated as hyperoside spectrophotometric method with aluminium(lll chloride as a colour reagent at 425 nm was applied. The total flavonoid content in the herbal material mixture was 0.483%, in 40% and 70% (v/v ethanolic liquid extract it was 138 mg/100 cm3 and 157 mg/100 cm, respectively. The extraction degree of total flavonoids with 40% and 70% (v/v ethanolic solutions was 57.14% and 65.01% respectively. The yield of total flavonoids in the dry extract was 63% in regard to the herbal mixure content.

Convective drying of hawthorn fruit (Crataegus spp.): Effect of experimental parameters on drying kinetics, color, shrinkage, and rehydration capacity.

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Aral, Serdar; Beşe, Ayşe Vildan

2016-11-01

Thin layer drying characteristics and physicochemical properties of hawthorn fruit (Crataegus spp.) were investigated using a convective dryer at air temperatures 50, 60 and 70°C and air velocities of 0.5, 0.9 and 1.3m/s. The drying process of hawthorn took place in the falling rate period, and the drying time decreased with increasing air temperature and velocity. The experimental data obtained during the drying process were fitted to eleven different mathematical models. The Midilli et al.'s model was found to be the best appropriate model for explaining the drying behavior of hawthorn fruit. Effective moisture diffusion coefficients (Deff) were calculated by Fick's diffusion model and their values varied from 2.34×10(-10)m(2)/s to 2.09×10(-9)m(2)/s. An Arrhenius-type equation was applied to determine the activation energies. While the shrinkage decreased, the rehydration ratio increased with increasing air temperature and air velocity. Copyright © 2016 Elsevier Ltd. All rights reserved.

The Hawthorne Effect: a randomised, controlled trial

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van Haselen Robbert

2007-07-01

Full Text Available Abstract Background The 'Hawthorne Effect' may be an important factor affecting the generalisability of clinical research to routine practice, but has been little studied. Hawthorne Effects have been reported in previous clinical trials in dementia but to our knowledge, no attempt has been made to quantify them. Our aim was to compare minimal follow-up to intensive follow-up in participants in a placebo controlled trial of Ginkgo biloba for treating mild-moderate dementia. Methods Participants in a dementia trial were randomised to intensive follow-up (with comprehensive assessment visits at baseline and two, four and six months post randomisation or minimal follow-up (with an abbreviated assessment at baseline and a full assessment at six months. Our primary outcomes were cognitive functioning (ADAS-Cog and participant and carer-rated quality of life (QOL-AD. Results We recruited 176 participants, mainly through general practices. The main analysis was based on Intention to treat (ITT, with available data. In the ANCOVA model with baseline score as a co-variate, follow-up group had a significant effect on outcome at six months on the ADAS-Cog score (n = 140; mean difference = -2.018; 95%CI -3.914, -0.121; p = 0.037 favouring the intensive follow-up group, and on participant-rated quality of life score (n = 142; mean difference = -1.382; 95%CI -2.642, -0.122; p = 0.032 favouring minimal follow-up group. There was no significant difference on carer quality of life. Conclusion We found that more intensive follow-up of individuals in a placebo-controlled clinical trial of Ginkgo biloba for treating mild-moderate dementia resulted in a better outcome than minimal follow-up, as measured by their cognitive functioning. Trial registration Current controlled trials: ISRCTN45577048

Hawthorn (Crataegus pinnatifida Bunge) leave flavonoids attenuate atherosclerosis development in apoE knock-out mice.

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Dong, Pengzhi; Pan, Lanlan; Zhang, Xiting; Zhang, Wenwen; Wang, Xue; Jiang, Meixiu; Chen, Yuanli; Duan, Yajun; Wu, Honghua; Xu, Yantong; Zhang, Peng; Zhu, Yan

2017-02-23

Hawthorn (Crataegus pinnatifida Bunge) leave have been used to treat cardiovascular diseases in China and Europe. Hawthorn leave flavonoids (HLF) are the main part of extraction. Whether hawthorn leave flavonoids could attenuate the development of atherosclerosis and the possible mechanism remain unknown. High-fat diet (HFD) mixed with HLF at concentrations of 5mg/kg and 20mg/kg were administered to apolipoprotein E (apoE) knock out mice. 16 weeks later, mouse serum was collected to determine the lipid profile while the mouse aorta dissected was prepared to measure the lesion area. Hepatic mRNA of genes involved in lipid metabolism were determined. Peritoneal macrophages were collected to study the impact of HLF on cholesterol efflux, formation of foam cell and the expression of ATP binding cassette transporter A1 (ABCA1). Besides, in vivo reverse cholesterol transport (RCT) was conducted. HLF attenuated the development of atherosclerosis that the mean atherosclerotic lesion area in en face aortas was reduced by 23.1% (Pflavonoids can slow down the development of atherosclerosis in apoE knockout mice via induced expression of genes involved in antioxidant activities, inhibition of the foam cell formation and promotion of RCT in vivo, which implies the potential use in the prevention of atherosclerosis. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

Simulation of Flow, Sediment Transport, and Sediment Mobility of the Lower Coeur d'Alene River, Idaho

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Berenbrock, Charles; Tranmer, Andrew W.

2008-01-01

A one-dimensional sediment-transport model and a multi-dimensional hydraulic and bed shear stress model were developed to investigate the hydraulic, sediment transport, and sediment mobility characteristics of the lower Coeur d?Alene River in northern Idaho. This report documents the development and calibration of those models, as well as the results of model simulations. The one-dimensional sediment-transport model (HEC-6) was developed, calibrated, and used to simulate flow hydraulics and erosion, deposition, and transport of sediment in the lower Coeur d?Alene River. The HEC-6 modeled reach, comprised of 234 cross sections, extends from Enaville, Idaho, on the North Fork of the Coeur d?Alene River and near Pinehurst, Idaho, on the South Fork of the river to near Harrison, Idaho, on the main stem of the river. Bed-sediment samples collected by previous investigators and samples collected for this study in 2005 were used in the model. Sediment discharge curves from a previous study were updated using suspended-sediment samples collected at three sites since April 2000. The HEC-6 was calibrated using river discharge and water-surface elevations measured at five U.S. Geological Survey gaging stations. The calibrated HEC-6 model allowed simulation of management alternatives to assess erosion and deposition from proposed dredging of contaminated streambed sediments in the Dudley reach. Four management alternatives were simulated with HEC-6. Before the start of simulation for these alternatives, seven cross sections in the reach near Dudley, Idaho, were deepened 20 feet?removing about 296,000 cubic yards of sediments?to simulate dredging. Management alternative 1 simulated stage-discharge conditions from 2000, and alternative 2 simulated conditions from 1997. Results from alternatives 1 and 2 indicated that about 6,500 and 12,300 cubic yards, respectively, were deposited in the dredged reach. These figures represent 2 and 4 percent, respectively, of the total volume of

Singing and Companionship in the Hawthorn University of the Third-Age Choir, Australia

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Joseph, Dawn; Southcott, Jane

2015-01-01

The international University of the Third Age (U3A) embodies the principles of lifelong learning and personal fulfilment amongst members. The research reported in this article focused on the Choir of the U3A Hawthorn, Melbourne, Australia and the benefits perceived by members undertaking this active music engagement in non-competitive choral…

Rock mechanics research in the Coeur d'Alene mining district

Energy Technology Data Exchange (ETDEWEB)

Corp, E. L.

1980-05-15

Over the past 20 years, the Bureau of Mines and mining companies of the Coeur d'Alene district have conducted cooperative research on problems of ground control. For the past six years emphasis has been placed on research to improve deep shaft design and to control rock bursts during cut-and-fill stoping. Finite-element modeling and construction of small-scale circular and rectangular test shafts have shown that circular openings are stable only when stresses are hydrostatic or weakly biaxial. Under a strongly-biaxial horizontal stress field, a rectangular shaft has a greater depth capability if its long axis can be oriented parallel to the major stress and normal to the bedding and joint system. Steel sets appear preferable to wood sets or concrete lining. Based on underground tests at Hecla's Star mine, destressing or preconditioning of the vein rock prior to mining was shown to be an effective means of controlling rock bursts. Drilling and shooting a radial pattern of longholes before stope mining starts has preconditioned or softened the vein material to the extent that seismic energy release during mining is reduced and no bursting occurred. Increased burst and seismic activity while mining about the preconditioned zone points out the need to precondition an entire stope block before mining.

Metal Transport, Heavy Metal Speciation and Microbial Fixation Through Fluvial Subenvironments, Lower Coeur D'Alene River Valley, Idaho

Science.gov (United States)

Hooper, R. L.; Mahoney, J. B.

2001-12-01

The lower Coeur d'Alene River Valley of northern Idaho is the site of extensive lead and zinc contamination resulting from both direct riverine tailings disposal and flood remobilization of contaminated sediments derived from the Coeur d'Alene mining district upstream. Variations in the hydrologic regime, redox conditions, porosity/permeability, organic content and microbial activity results in complicated metal transport pathways. Documentation of these pathways is a prerequisite to effective remediation, and requires accurate analysis of lateral and vertical variations. An analytical approach combining sequential extraction, electron microscopy, and microanalysis provides a comprehensive assessment of particulate speciation in this complex hydrologic system. Rigorously controlled sample preparation and a new sequential extraction protocol provide unprecedented insight into the role of metal sequestration in fluvial subenvironments. Four subenvironments were investigated: bedload, overbank (levee), marsh, and lacustrine. Periodic floods remobilize primary ore minerals and secondary minerals from upstream tailings (primarily oxyhydroxides, sulfides and carbonates). The bedload in the lower valley is a reducing environment and acts as a sink for detrital carbonates and sulfides moving downstream. In addition, authigenic/biogenic Fe, Pb and Zn sulfides and phosphates are common in bedload sediments near the sediment/water interface. Flood redistribution of oxide, sulfide and carbonate phases results in periodic contaminant recharge generating a complex system of metal dissolution, mobilization, migration and precipitation. In levee environments, authigenic sulfides from flood scouring are quickly oxidized resulting in development of oxide coated grain surfaces. Stability of detrital minerals on the levee is variable depending on sediment permeability, grain size and mineralogy resulting in a complex stratigraphy of oxide zones mottled with zones dominated by detrital

Physico-chemical, antioxidant, and anti-inflammatory properties and stability of hawthorn (Crataegus monogyna Jacq.) procyanidins microcapsules with inulin and maltodextrin.

Science.gov (United States)

Wyspiańska, Dorota; Kucharska, Alicja Z; Sokół-Łętowska, Anna; Kolniak-Ostek, Joanna

2017-01-01

Procyanidins from the bark of hawthorn (Crataegus monogyna Jacq.) were isolated and purified. Qualitative and quantitative composition was compared with that of the extract of hawthorn fruit (Crataegus monogyna Jacq.). Stability and antioxidant and anti-inflammatory properties of procyanidins before and after micro-encapsulation were estimated. The effects of the carrier type (inulin and maltodextrin) and procyanidins:carrier ratio (1:1, 1:3) and the influence of storage temperature (20 °C, -20 °C, -80 °C) on the content of procyanidins were evaluated. Samples before and after micro-encapsulation contained from 651 to 751 mg of procyanidins in 1 g. Among the procyanidins, (-)-epicatechin, dimer B2, and trimer C1 dominated. The use of inulin during spray drying resulted in greater efficiency of micro-encapsulation than the use of maltodextrin. During storage of the samples at 20 °C degradation of procyanidins was observed, whereas at -20 °C and -80 °C concentrations of them increased. The microcapsules with procyanidins from the bark of hawthorn, as well as the extract of procyanidins, have valuable biological activity, and strong antioxidant and anti-inflammatory properties. It is better to prepare microcapsules with a greater amount of carrier, with the procyanidin/carrier ratio 1:3. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

The Effect of Ambient Water Quality on Lakefront Property Values: Evidence from Coeur d'Alene, Idaho

Science.gov (United States)

Liao, H.

2015-12-01

Climate warming is causing water temperatures to increase and subsequent changes in water quality. To develop innovative approaches for mitigating the possible negative social consequences of such changes, more research efforts are needed to investigate how people perceive and respond to ambient water quality. This research examines the amenity value of water quality in the areas centered on Lake Coeur d'Alene of Northern Idaho. Through a hedonic analysis, we find that two important water-quality variables have had significant effects on lakefront property values, including Secchi disc reading, a technical measure of water clarity, and the presence of Eurasian watermilfoil, an aquatic invasive species. We further explore the spatial heterogeneity of water-quality benefits along the urban-rural gradient and find that access to urban amenities has strengthened the water-quality benefits in the lakefront housing market. Our findings could be used to incentivize private property owners and stakeholders to commit time and funding to cope with the potential degradation of water quality under climate change.

Determination of selected toxic elements in leaves of White Hawthorn grown in a remote area

Directory of Open Access Journals (Sweden)

Zeiner M.

2013-04-01

Full Text Available One important plant of the Rosaceae family which is commonly used as phytopharmaceutical in Europe and North America is Hawthorn (Crataegus monogyna. The fruits, the leaves together with their extracts are applied in patients suffering mild cardiac disorders or nervosity. Since the leaves as well as the berries act as diuretics a sufficient micronutrient supply has to be guaranteed. On the other the quantities of toxic elements present in the plant parts should be at levels without harmful effects on human health. For this purpose Hawthorn leaves and flowers were collected in a remote area in 2011 and 2012 and analysed for their elemental composition. The metals uptaken from the soil were supposed to be in a similar range, thus the impact of airborne contamination by heavy metal translocation could be studied. The elements investigated were Ba, Cd, Co, Cr, Cu, Mn, Ni, Pb, Sr, and Zn. After harvesting the samples were dried, homogenized, digested and then analysed by ICP-AES. The contents of all elements are in the μg/g range. In the samples of 2012 higher concentrations were found for Co, Cu, Mn, Ni, and Zn, lower concentrations were registered for Ba, Pb, and Sr. The amounts of Cd and Cr were statistically insignificantly lower in 2012 than 2011.

Rock mechanics research in the Coeur d'Alene mining district

Energy Technology Data Exchange (ETDEWEB)

Corp, E. L.

1980-05-15

Over the past 20 years, the Bureau of Mines and mining companies of the Coeur d'Alene district have conducted cooperative research on problems of ground control. For the past six years emphasis has been placed on research to improve deep shaft design and to control rock bursts during cut-and-fill stoping. Factors contributing to ground control problems include: depth of mining ranging to 8000 feet; local tectonic activity that in many instances has produced horizontal stresses exceeding the vertical; unequal horizontal stresses at ratios ranging between 1.25 and 2.73; major faults, joints, and bedding planes; and hard, brittle quartzite rock capable of concentrating high levels of stress. Finite-element modeling and construction of small-scale circular and rectangular test shafts have shown that circular openings are stable only when stresses are hydrostatic or weakly biaxial. Under a strongly-biaxial horizontal stress field, a rectangular shaft has a greater depth capabiity if its long axis can be oriented parallel to the major stress and normal to the bedding and joint system. Steel sets appear preferable to wood sets or concrete lining. Based on underground tests at Hecla's Star mine, destressing or preconditioning of the vein rock prior to mining was shown to be an effective means of controlling rock bursts. Drilling and shooting a radial pattern of longholes before stope mining starts has preconditioned or softened the vein material to the extent that seismic energy release during mining is reduced and no bursting occurred. Increased burst and seismic activity while mining above the preconditioned zone points out the need to precondition an entire stope block before mining.

Stream-sediment geochemistry in mining-impacted streams: Prichard, Eagle, and Beaver creeks, northern Coeur d'Alene Mining District, northern Idaho

Science.gov (United States)

Box, Stephen E.; Wallis, John C.; Briggs, Paul H.; Brown, Zoe Ann

2005-01-01

This report presents the results of one aspect of an integrated watershed-characterization study that was undertaken to assess the impacts of historical mining and milling of silver-lead-zinc ores on water and sediment composition and on aquatic biota in streams draining the northern part of the Coeur d?Alene Mining District in northern Idaho. We present the results of chemical analyses of 62 samples of streambed sediment, 19 samples of suspended sediment, 23 samples of streambank soil, and 29 samples of mine- and mill-related artificial- fill material collected from the drainages of Prichard, Eagle, and Beaver Creeks, all tributaries to the North Fork of the Coeur d?Alene River. All samples were sieved into three grain-size fractions (Beaver Creek drainages has resulted in enrichments of lead, zinc, mercury, arsenic, cadmium, silver, copper, cobalt, and, to a lesser extent, iron and manganese in streambed sediment. Using samples collected from the relatively unimpacted West Fork of Eagle Creek as representative of background compositions, streambed sediment in the vicinity of the mines and millsites has Pb and Zn contents of 20 to 100 times background values, decreasing to 2 to 5 times background values at the mouth of the each stream, 15 to 20 km downstream. Lesser enrichments (<10 times background values) of mercury and arsenic also are generally associated with, and decrease downstream from, historical silver-lead-zinc mining in the drainages. However, enrichments of arsenic and, to a lesser extent, mercury also are areally associated with the lode gold deposits along Prichard Creek near Murray, which were not studied here. Metal contents in samples of unfractionated suspended sediment collected during a high-flow event in April 2000 are generally similar to, but slightly higher than, those in the fine (<0.063- mm grain size) fraction of streambed sediment from the same sampling site. Although metal enrichment in streambed sediment typically begins adjacent to

Study of Spatial Distribution of the Hawthorn (Crataegus monogyna Trees Attacked by Orchard Ermine (Yponomeuta padella in Bazoft Forests of Chaharmahal and Bakhtiari Province

Directory of Open Access Journals (Sweden)

H. Shariati Najaf Abadi

2016-03-01

Full Text Available Forest trees demonstrate different distribution patterns, depend on their living condition (Such as pest infestations. Forest density and epidemic pest concentration are hypothetically among the most influential factors. The current study was carried out on distribution pattern of the orchard ermine (Yponomeuta padella infested hawthorn trees (Crataegus monogyna in Bazoft river watershed in Central Zagros. Nine sites were selected with different infections. The site selection was based on pollution and position (North or South it. Pollution, density of trees and coordinates (X , Y were recorded for each tree. Eberhart and Ripley’s K functions were used to elucidate the infested and non-infested tree distribution. The results showed a clumped distribution of the trees in sound sites and in infested sites with high hawthorn density. Trees in low-dense infested sites had a tendency toward more random and even uniform population distribution.

Improvements to the Understanding of the Fire Performance of Wood over the Past 30 Years-A Tribute to Robert Hawthorne White

Science.gov (United States)

Samuel L. Zelinka; Mark A. Dietenberger; Laura E. Hasburgh; Keith J. Bourne; Charles Boardman

2015-01-01

Dr. Robert Hawthorne White had a 31 year career researching the fire performance of wood and wood composites at the USDA Forest Products Laboratory. Over his career, Dr. White made substantial contributions to codes, standards, and regulations pertaining to the design of wood structures. This review article summarizes Robert’s major accomplishments as a tribute to his...

"The most important technique …": Carl Rogers, Hawthorne, and the rise and fall of nondirective interviewing in sociology.

Science.gov (United States)

Lee, Raymond M

2011-01-01

In the 1940s, interviewing practice in sociology became decisively influenced by techniques that had originally been developed by researchers in other disciplines working within a number of therapeutic or quasi-therapeutic contexts, in particular the "nondirective interviewing" methods developed by Carl Rogers and the interviewing procedures developed during the Hawthorne studies. This article discusses the development of nondirective interviewing and looks at how in the 1930s and '40s the approach came to be used in sociology. It examines the factors leading to both the popularity of the method and its subsequent fall from favor. © 2011 Wiley Periodicals, Inc.

Quantification of the Hawthorne effect in hand hygiene compliance monitoring using an electronic monitoring system: a retrospective cohort study.

Science.gov (United States)

Srigley, Jocelyn A; Furness, Colin D; Baker, G Ross; Gardam, Michael

2014-12-01

The Hawthorne effect, or behaviour change due to awareness of being observed, is assumed to inflate hand hygiene compliance rates as measured by direct observation but there are limited data to support this. To determine whether the presence of hand hygiene auditors was associated with an increase in hand hygiene events as measured by a real-time location system (RTLS). The RTLS recorded all uses of alcohol-based hand rub and soap for 8 months in two units in an academic acute care hospital. The RTLS also tracked the movement of hospital hand hygiene auditors. Rates of hand hygiene events per dispenser per hour as measured by the RTLS were compared for dispensers within sight of auditors and those not exposed to auditors. The hand hygiene event rate in dispensers visible to auditors (3.75/dispenser/h) was significantly higher than in dispensers not visible to the auditors at the same time (1.48; p=0.001) and in the same dispensers during the week prior (1.07; pHand hygiene event rates were approximately threefold higher in hallways within eyesight of an auditor compared with when no auditor was visible and the increase occurred after the auditors' arrival. This is consistent with the existence of a Hawthorne effect localised to areas where the auditor is visible and calls into question the accuracy of publicly reported hospital hand hygiene compliance rates. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Isolation and identification of flavonoids, including flavone rotamers, from the herbal drug 'Crataegi folium cum flore' (hawthorn).

Science.gov (United States)

Rayyan, S; Fossen, T; Solheim Nateland, H; Andersen, O M

2005-01-01

Twelve flavonoids, including seven flavones, four flavonols and one flavanone, were isolated from methanolic extract of the herbal drug 'Crataegi folium cum flore' (hawthorn leaves and flowers) by a combination of CC (over Amberlite XAD-7 and Sephadex LH-20) and preparative HPLC. Their structures, including that of the novel flavonol 8-methoxykaempferol 3-O-(6"-malonyl-beta-glucopyranoside), were elucidated by homo- and heteronuclear NMR and electrospray/MS. The 1H- and 13C-NMR of all compounds, including rotameric pairs of five flavone C-glycosides, were assigned. The presence and relative proportion of each rotamer was shown by various NMR experiments, including two-dimensional nuclear Overhauser and exchange spectroscopy, to depend on solvent, linkage position and structure of the C-glycosyl substituent.

Nanomechanics and sodium permeability of endothelial surface layer modulated by hawthorn extract WS 1442.

Directory of Open Access Journals (Sweden)

Wladimir Peters

Full Text Available The endothelial glycocalyx (eGC plays a pivotal role in the physiology of the vasculature. By binding plasma proteins, the eGC forms the endothelial surface layer (ESL which acts as an interface between bloodstream and endothelial cell surface. The functions of the eGC include mechanosensing of blood flow induced shear stress and thus flow dependent vasodilation. There are indications that levels of plasma sodium concentrations in the upper range of normal and beyond impair flow dependent regulation of blood pressure and may therefore increase the risk for hypertension. Substances, therefore, that prevent sodium induced endothelial dysfunction may be attractive for the treatment of cardiovascular disease. By means of combined atomic force-epifluorescence microscopy we studied the impact of the hawthorn (Crataegus spp. extract WS 1442, a herbal therapeutic with unknown mechanism of action, on the mechanics of the ESL of ex vivo murine aortae. Furthermore, we measured the impact of WS 1442 on the sodium permeability of endothelial EA.hy 926 cell monolayer. The data show that (i the ESL contributes by about 11% to the total endothelial barrier resistance for sodium and (ii WS 1442 strengthens the ESL resistance for sodium up to about 45%. This mechanism may explain some of the vasoprotective actions of this herbal therapeutic.

Quality Comparison of Hawthorn Wines Fermented by Saccharomyces cerevisiae with and without Pulp Contact and Pectase Treatment

Directory of Open Access Journals (Sweden)

Wenye Zhang

2017-01-01

Full Text Available This study evaluated the chemical and volatile composition of hawthorn wines fermented with Saccharomyces cerevisiae A3.12 with and without pulp contact and pectase treatment during fermentation. The results indicated that the addition of pectase was in favor of pH decrease and clarification. The pectase-treated wines had significantly higher concentrations of acetic acid, ethyl octanoate, and isoamyl acetate than the non-enzyme-treated wines. Furthermore, the nonextracted wines had significantly higher concentrations of isoamyl alcohol, phenylethyl alcohol, ethyl lactate, and isoamyl acetate than the extracted wines. The first principal component separated the wine from the nonextracted juice with pectase from other samples based on the higher concentrations of isoamyl acetate (0.14 μg/g, diethyl butanedioate (0.07 μg/g, 2-phenylethyl acetate (0.23 μg/g, and acetoin (1.47 μg/g. The wine from nonextracted pulpy juice with pectase was significantly more aromatic than the others and 26.2% of the consumers were found to be willing to purchase this product.

7 CFR 953.322 - Handling regulation.

Science.gov (United States)

2010-01-01

... Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE IRISH POTATOES GROWN IN..., potatoes for dehydration, chips, shoestrings, starch, and flour. It includes only that preparation of...

7 CFR 948.386 - Handling regulation.

Science.gov (United States)

2010-01-01

... Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE IRISH POTATOES GROWN IN COLORADO... is not restricted to, potatoes for dehydration, chips, shoestrings, starch, and flour. It includes...

7 CFR 947.340 - Handling regulation.

Science.gov (United States)

2010-01-01

... Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE IRISH POTATOES GROWN IN MODOC AND... the act and includes, but is not restricted to, potatoes for dehydration, chips, shoestrings, or...

A Scientific World in a Grain of Sand

Science.gov (United States)

Clary, Renee; Wandersee, James

2011-01-01

Students investigate local sand samples on a shoestring budget. This investigation reveals a fascinating Earth history that can address various interdisciplinary scientific topics, provide rich inquiry experiences, and move beyond the science classroom to integrate history, culture, and art. (Contains 3 figures and 14 online resources.)

Role of neutron activation analysis in the study of heavy metal pollution of a lake-river system

International Nuclear Information System (INIS)

Filby, R.H.; Shah, K.R.; Funk, W.H.

1974-01-01

Details of a study of combined organic and metallic pollution of the Coeur d'Alene Lake-River and Spokane River system and the role played by nuclear techniques in the investigation are presented. The Coeur d'Alene River drains through the N. Idaho Pb--Zn mining region of Kellogg and the mining industry is the major source of metallic pollution of the lake and river system. The first part of the study has involved the determination of Pb, Zn, Ag, Cd, As, Cu, Sb, Co, Cr, Cs, Rb, Sc, Ba, Eu, La, Tb, Y, Zr, Fe, Mn, Mo, by INAA in waters, sediments and organisms throughout the region. Extremely high values for Pb, Zn, Sb, Fe and other metals were found in the Coeur d'Alene River delta sediments and in the lake sediments. Results from the study of metals in an aquatic ecosystem show the value of combining nuclear techniques with other methods of trace analysis in practical pollution problems

Distribution of metals during digestion by cutthroat trout fed benthic invertebrates contaminated in the Clark Fork River, Montana and the Coeur d'Alene River, Idaho, U.S.A., and fed artificially contaminated Artemia

Science.gov (United States)

Farag, A.M.; Suedkamp, M.J.; Meyer, J.S.; Barrows, R.; Woodward, D.F.

2000-01-01

The concentrations of essential amino acids in three, undigested invertebrate diets collected from the Clark Fork River (CFR) for cutthroat trout were similar to each other, but were c. 25–75% less than Artemia that were exposed to a mixture of arsenic, copper, cadmium, lead and zinc in the laboratory. The Artemia diet appeared less palatable and the texture, quantity and appearance of the intestinal contents differed between fish fed the Artemia and CFR diets. The Pb% in the fluid fraction of the intestinal contents was greater for the Artemia (29%) than for the CFR diets (10–17%), and the Cu% in the amino acid plus metal fraction of the intestinal contents was greater for the Artemia (78%) than for two of the three CFR diets (67% and 70%). Intestinal contents of fish fed invertebrate diets collected from various sites on the Coeur d'Alene River (CDA), Idaho, were similar in texture, quantity, and appearance. For fish fed the CDA diets, differences in the distribution of metals among fractions of the digestive fluids appeared to be related to concentrations of metals in the invertebrate diets. Pb% was lowest of all metals in the fluid portion of the intestinal contents. However, >80% of all metals in the hind gut were associated with the particulate fraction where they may still be available for uptake through pinocytosis.

Disaster at a University: A Case Study in Information Security

Science.gov (United States)

Ayyagari, Ramakrishna; Tyks, Jonathan

2012-01-01

Security and disaster training is identified as a top Information Technology (IT) required skill that needs to be taught in Information Systems (IS) curriculums. Accordingly, information security and privacy have become core concepts in information system education. Providing IT security on a shoestring budget is always difficult and many small…

Hawthorne effect with transient behavioral and biochemical changes in a randomized controlled sleep extension trial of chronically short-sleeping obese adults: implications for the design and interpretation of clinical studies.

Directory of Open Access Journals (Sweden)

Giovanni Cizza

Full Text Available To evaluate the effects of study participation per se at the beginning of a sleep extension trial between screening, randomization, and the run-in visit.Subjects were screened, returned for randomization (Comparison vs. Intervention after 81 days (median, and attended run-in visit 121 days later.Outpatient.Obese (N = 125; M/F, 30/95; Blacks/Whites/Other, N = 73/44/8, mean weight 107.6±19.7 kg, <6.5 h sleep/night.Non-pharmacological sleep extension.Sleep duration (diaries and actigraphy watch, sleep quality (Pittsburgh Sleep Quality Index, daily sleepiness (Epworth Sleepiness Scale, fasting glucose, insulin and lipids.Prior to any intervention, marked improvements occurred between screening and randomization. Sleep duration increased (diaries: 357.4 ±51.2 vs. 388.1±48.6 min/night; mean±SD; P<0.001 screening vs. randomization; actigraphy: 344.3 ±41.9 vs. 358.6±48.2 min/night; P<0.001 sleep quality improved (9.1±3.2 vs. 8.2±3.0 PSQI score; P<0.001, sleepiness tended to improve (8.9±4.6 vs. 8.3±4.5 ESS score; P = 0.06, insulin resistance decreased (0.327±0.038 vs. 0.351±0.045; Quicki index; P<0.001, and lipids improved, except for HDL-C. Abnormal fasting glucose (25% vs. 11%; P = 0.007, and metabolic syndrome (42% vs. 29%; P = 0.007 both decreased. In absence of intervention, the earlier metabolic improvements disappeared at the run-in visit.Relatively small sample size.Improvements in biochemical and behavioral parameters between screening and randomization changed the "true" study baseline, thereby potentially affecting outcome. While regression to the mean and placebo effect were considered, these findings are most consistent with the "Hawthorne effect", according to which behavior measured in the setting of an experimental study changes in response to the attention received from study investigators. This is the first time that biochemical changes were documented with respect to the Hawthorne effect. The findings

Imaging Emission Spectra with Handheld and Cellphone Cameras

Science.gov (United States)

Sitar, David

2012-01-01

As point-and-shoot digital camera technology advances it is becoming easier to image spectra in a laboratory setting on a shoestring budget and get immediate results. With this in mind, I wanted to test three cameras to see how their results would differ. Two undergraduate physics students and I used one handheld 7.1 megapixel (MP) digital Cannon…

Effects of dietary hawthorn extract on growth performance, immune responses, growth- and immune-related genes expression of juvenile golden pompano (Trachinotus ovatus) and its susceptibility to Vibrio harveyi infection.

Science.gov (United States)

Tan, Xiaohong; Sun, Zhenzhu; Huang, Zhong; Zhou, Chuanpeng; Lin, Heizhao; Tan, Lianjie; Xun, Pengwei; Huang, Qian

2017-11-01

The present study was conducted to investigate the effects of dietary hawthorn extract (HTE) supplementation on growth performance, immune responses, hepatic antioxidant abilities, growth- and immune-related and heat shock protein genes expression and resistance to the pathogen Vibrio harveyi in Trachinotus ovatus. A basal diet supplemented with HTE at 0 (Diet 1), 0.50 (Diet 2), 1.00 (Diet 3), 2.00 (Diet 4), 4.00 (Diet 5) and 10.00 (Diet 6) g kg -1 were fed to golden pompano for 8 weeks. The highest final body weight, weight gain rate, specific growth rate, feed efficiency ratio and protein efficiency rate were observed in fish fed Diet 2 (P Vibrio harveyi, significant higher post-challenge survival was observed in fish fed Diet 2 and Diet 3 than the control group (P growth-related genes (IGF-I and IGF-II) were significantly up-regulated in fish fed HTE supplement (P growth performance and growth-related genes expression, strengthen immunity, and improve hepatic antioxidative abilities and resistance to Vibrio harveyi infection. Copyright © 2017 Elsevier Ltd. All rights reserved.

Training on a Shoestring.

Science.gov (United States)

Callahan, Madelyn R.

1995-01-01

Describes ways to train employees on a tight budget and cut training costs. Offers ideas such as using local colleges, negotiating outsourcing costs, using computers, making good use of experts, and sharing resources with other companies. (JOW)

Marketing on a shoestring.

Science.gov (United States)

Sutton, J

1999-01-01

Marketing includes the many steps taken to sell a product or service from its conception to its purchase or use. In healthcare, three cost-effective audiences to target are referring physicians and their staffs, local HMOs and PPOs, facility employees and patients. The potential users of such services--your target audience--should be made aware of new offerings such as the addition of special procedures, a new piece of equipment, or perhaps a new physician with special capabilities. To ensure a productive effort, a marketing attempt must follow two cardinal rules: first, the product or service offered must be of high quality and, second, the marketing effort must be carried out consistently. An effective marketing campaign should create an impression within the community about the facility by emphasizing those aspects of the department or facility that make it unique. Are its hours of operation adequate? Do its personnel project a professional attitude and demeanor? Does it have a specialty that makes it unique within the healthcare community? The most powerful marketing tool of all is word of mouth, which is based on the judgments clients make after visiting the facility-department or facility employees smile and greet visitors, they are polite and helpful on the telephone, their attitudes are professional, and so forth. Such impressions are worth millions in goodwill and can be used as a marketing tool. Last, an actual case study from my hospital explains how we determined the need for and marketed an open MRI system.

Influence of the extraction mode on the yield of hyperoside, vitexin and vitexin-2''-O-rhamnoside from Crataegus monogyna Jacq. (hawthorn).

Science.gov (United States)

Martino, Emanuela; Collina, Simona; Rossi, Daniela; Bazzoni, Deborah; Gaggeri, Raffaella; Bracco, Francesco; Azzolina, Ornella

2008-01-01

The extract of Crataegus monogyna shows sedative, hypotensive, vasodilator and cardio-tonic actions. Although several papers dealing with the extraction of metabolites from Crataegus have been published, the plant productivity in terms of bioactive compounds is not easily understandable as yet. To investigate the influence of the extraction mode on the yield of bioactive compounds from Crataegus monogyna Jacq. in order to evaluate plant productivity. Samples were prepared by extraction of powdered material obtained from top branches, flowers and leaves. Soxhlet extraction, maceration and ultrasound- and microwave-assisted extraction at different experimental conditions were investigated for the exhaustive extraction of hyperoside, vitexin and vitexin-2''-O-rhamnoside. The phytocomponents were identified and quantified by HPLC-UV/PAD, comparing HPLC retention times and UV spectra of individual peaks with those of the standards analysed under the same conditions. An easy-to-use HPLC isocratic method suitable for the quantification of hyperoside, vitexin and vitexin-2''-O-rhamnoside in raw plant extracts was developed. The optimised HPLC methodology was applied to evaluate different extraction procedures. The ultrasound and microwave-assisted extraction protocols showed higher extraction efficiency than the others. In particular, the optimised microwave protocol gave rise to the highest extraction efficiency with high reproducibility. A microwave protocol combined with isocratic HPLC analysis is proposed for the rapid screening of plant materials collected in different environmental conditions in order to evaluate the productivity of Crataegus monogyna Jacq. and to find out the best ecological conditions to cultivate hawthorn in Northern Italy.

76 FR 40600 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

Science.gov (United States)

2011-07-11

..., AR, Adams Field, RNAV (GPS) RWY 18, Amdt 1A Hawthorne, CA, Jack Northrop Field/Hawthorne Muni, RNAV... Ridder, LA, Beauregard Rgnl, RADAR 1, Orig-A, CANCELLED Beverly, MA, Beverly Muni, RNAV (GPS) RWY 16...

Hawthorne effect with transient behavioral and biochemical changes in a randomized controlled sleep extension trial of chronically short-sleeping obese adults: implications for the design and interpretation of clinical studies.

Science.gov (United States)

Cizza, Giovanni; Piaggi, Paolo; Rother, Kristina I; Csako, Gyorgy

2014-01-01

To evaluate the effects of study participation per se at the beginning of a sleep extension trial between screening, randomization, and the run-in visit. Subjects were screened, returned for randomization (Comparison vs. Intervention) after 81 days (median), and attended run-in visit 121 days later. Outpatient. Obese (N = 125; M/F, 30/95; Blacks/Whites/Other, N = 73/44/8), mean weight 107.6±19.7 kg, sleep/night. Non-pharmacological sleep extension. Sleep duration (diaries and actigraphy watch), sleep quality (Pittsburgh Sleep Quality Index), daily sleepiness (Epworth Sleepiness Scale), fasting glucose, insulin and lipids. Prior to any intervention, marked improvements occurred between screening and randomization. Sleep duration increased (diaries: 357.4 ±51.2 vs. 388.1±48.6 min/night; mean±SD; Psleep quality improved (9.1±3.2 vs. 8.2±3.0 PSQI score; Pattention received from study investigators. This is the first time that biochemical changes were documented with respect to the Hawthorne effect. The findings have implications for the design and conduct of clinical research. ClinicalTrials.gov NCT00261898.

Shoestring Budget Radio Astronomy (Abstract)

Science.gov (United States)

Hoot, J. E.

2017-12-01

(Abstract only) The commercial exploitation of microwave frequencies for cellular, WiFi, Bluetooth, HDTV, and satellite digital media transmission has brought down the cost of the components required to build an effective radio telescope to the point where, for the cost of a good eyepiece, you can construct and operate a radio telescope. This paper sets forth a family of designs for 1421 MHz telescopes. It also proposes a method by which operators of such instruments can aggregate and archive data via the Internet. With 90 or so instruments it will be possible to survey the entire radio sky for transients with a 24 hour cadence.

Laser spectroscopy on a ''shoestring''

International Nuclear Information System (INIS)

Camparo, J.C.; Klimcak, C.M.

1983-01-01

The advent of tunable lasers has had a profound influence on both experimental and theoretical physics. Unfortunately, since these laser systems are typically hazardous and expensive, the physics student at the undergraduate or first-year graduate level has no real familiarity with their application in modern physics; and thus cannot fully appreciate their significance. Tunable single mode laser diodes, however, may offer a remedy to this situation. To demonstrate their applicability, we have designed a relatively simple and inexpensive experiment of laser diode spectroscopy in an atomic beam which illustrates the effect of hyperfine structure and the isotope shift in the rubidium D 1 transition (5 2 S/sub 1/2/-5 2 P/sub 1/2/). Furthermore, this experiment demonstrates the possibility of investigating basic physics without major expenditures for laser systems and laboratory facilities

Data Base Management: Proceedings of a Conference, November 1-2, 1984 Held at Monterey, California.

Science.gov (United States)

1985-07-31

basically been a "hobby" done on a shoestring budget. These constraints show up in the CODA code as a paucity of " gorilla proofing" and shortage of pme...animal anatomy published between the year 1550 and 1860, adapted from a paper published in 1917 by Cole and Eales. This data is the oldest quantitative...Of particular note is their comment that, in the first hundred years of anatomy publication the pattern was sporadic because

Evaluation of Hypolipidemic and Antioxidant Effects in Phenolrich Fraction of Crataegus pinnatifida Fruit in Hyperlipidemia Rats and Identification of Chemical Composition by Ultra-performance Liquid Chromatography Coupled with Quadropole Time-of-flight Mass Spectrometry

Science.gov (United States)

Shao, Feng; Gu, Lifei; Chen, Huijuan; Liu, Ronghua; Huang, Huilian; Chen, Lanying; Yang, Ming

2017-01-01

Background: Hawthorn (Crataegus pinnatifida) fruit has enjoyed a great popularity as a pleasant-tasting food associated with hypolipidemic and antioxidant effects. Objective: Our aim was to screen the effective fraction of hawthorn fruit in the treatment of hyperlipidemia rats. Materials and Methods: In this study, ethanol extract of hawthorn fruit (Fr.1) and four fractionated extracts (Fr.2, Fr.3, Fr.4, and Fr.5) were compared to total phenol content evaluated using Folin–Ciocalteu method, and hypolipidemic and antioxidant effects were assessed in hyperlipidemic rats. Results: Total phenol content of Fr.4 was higher than other fractions by at least 2 fold. Furthermore, this fraction possessed the strongest hypolipidemic and antioxidant effects in hyperlipidemic rats. On this basis, 15 phenolic compounds and four organic acids in Fr.4 were positively or tentatively identified using ultra-performance liquid chromatography coupled with quadropole time-of-flight mass spectrometry. In addition, 5-O-caffeoyl quinic acid butyl ester was first reported in hawthorn fruit. Conclusion: Phenol-rich fraction in hawthorn fruit exhibited satisfactory hypolipidemic and antioxidant effects, and this could be exploited for further promotion of functional foods. SUMMARY Phenol-rich fraction in hawthorn fruit possesses most potent hypolipidemic and antioxidant effects in hyperlidemia rats. Abbreviations used: UPLC-Q-TOF-MS/MS: Ultra performance liquid chromatography coupled with quadropole time-of-flight mass spectrometry; TC: Total cholesterol; TG: Triglyceride; LDL-C: Low-density lipoprotein-cholesterol; HDL-C: High-density lipoprotein-cholesterol; GSH-Px: Glutathione peroxidase; SOD: Superoxide dismutase; MDA: Malondialdehyde; CAT: Catalase; NO: Nitric oxide; NOS: Nitric oxide synthase; ROS: Reactive oxygen species; •OOH: Superoxide anions, •OH: Hydroxyl radicals. PMID:29200740

Phytomining Perspectives in Rehabilitation of Mining and Industrial Areas of South Ural

Science.gov (United States)

Timofeeva, S. S.; Ulrikh, D. V.; Timofeev, S. S.

2017-05-01

The ability of midland hawthorn (Crataegus laevigata (Poir)), common barberry (Berberis vulgaris), red elder (Sambucus racemosa), cinnamon rose (Rosa cinnamomea L.), couch grass (Elytrigia repens), crested wheat grass (Agropyron cristatum), meadow fescue (Festuca pratensis) and meadow grass (Poa pratensis) for phytoextraction of heavy metals from technogenic soil is proved in the article. The possibility of effective phytoextraction with the use of hawthorn and elder is shown. Maximum accumulation of zinc takes place in the surface mass of couch grass and meadow fescue. In regard to the conditions of South Ural, planting of elder and hawthorn with seeding of couch grass and meadow fescue is recommended for phytomining purposes.

Young Scientist Wetenschapskalender 2018

NARCIS (Netherlands)

van Dalen-Oskam, K.H.; van Zundert, Joris J.; Koolen, Corina

2017-01-01

Bijdragen scheurkalender Young Scientist Wetenschapskalender 2018. Karina van Dalen-Oskam, Belangrijk woord: Wat is het belangrijkste woord in de Nederlandse taal? In: Young Scientist Wetenschapskalender 2018, 1 september Corina Koolen, Op naar het boekenbal: Hoe wordt je beroemd als schrijver? In:

Seasonal distributions of the western cherry fruit fly (Diptera: Tephritidae) among host and nonhost fruit trees.

Science.gov (United States)

Yee, Wee L

2014-01-01

Seasonal distributions of the western cherry fruit fly, Rhagoletis indifferens Curran (Diptera: Tephritidae), in sweet cherry (Prunus avium (L.) L.) (major host), black hawthorn (occasional developmental host) (Crataegus douglasii Lindley), and other trees were determined in a ponderosa pine ecosystem in Washington state, USA. The hypothesis that most fly dispersal from cherry trees occurs after fruit senesce or drop was tested, with emphasis on movement to black hawthorn trees. Sweet cherry fruit developed earlier than black hawthorn, bitter cherry (common host), choke cherry, and apple fruit. Flies were usually captured first in sweet cherry trees but were caught in bitter cherry and other trees throughout the season. Peak fly capture periods in sweet cherry began around the same time or slightly earlier than in other trees. However, peak fly capture periods in black hawthorn and other nonsweet cherry trees continued after peak periods in sweet cherry ended, or relative fly numbers within sweet cherry declined more quickly than those within other trees. Larvae were reared from sweet and bitter cherry but not black hawthorn fruit. Results provide partial support for the hypothesis in that although R. indifferens commonly disperses from sweet cherry trees with fruit, it could disperse more, or more flies are retained in nonsweet cherry trees after than before sweet cherries drop. This could allow opportunities for the flies to use other fruit for larval development. Although R. indifferens infestation in black hawthorn was not detected, early season fly dispersal to this and other trees and fly presence in bitter cherry could make fly management in sweet cherry difficult. Published by Oxford University Press on behalf of the Entomological Society of America 2014. This work is written by a US Government employee and is in the public domain in the US.

Starters slaan hun slag! : woningmarkt in de uitverkoop

NARCIS (Netherlands)

Francke, M.; van de Minne, A.

2013-01-01

Woningprijzen in Nederland dalen al sinds 2008. De gevolgen zijn groot: inmiddels staan naar schatting een miljoen huishoudens onder water. Echter, jonge huishoudens die nog willen starten op de koopwoningmarkt kunnen door de dalende woningprijzen en de lage hypotheekrente woningen kopen die

Mindfulnesstraining voor aiossen psychiatrie : een pilotstudie

NARCIS (Netherlands)

Hoenders, H J R; Booij, S H; Knegtering, H; van den Brink, H

2016-01-01

ACHTERGROND Medisch studenten en artsen in opleiding tot specialist (aiossen) hebben een verhoogd risico op burn-out. Bovendien lijkt bij medisch studenten het niveau van empathie te dalen tijdens de studie. Dit lijkt gerelateerd aan een hoog stressniveau. Op mindfulness gebaseerde interventies

Runtime Speculative Software-Only Fault Tolerance

Science.gov (United States)

2012-06-01

Threading DAFT [67] 1× Yes 2 - Most None 38% - Process-based PLR [49] 2× No 2 3 Most Some 16.9% 41% Redundancy RSFT[This Thesis] 2× No 2 2 Most All 3.54...with lower fault cover- age. Redundant multi-threading techniques (e.g. SRMT [60] and DAFT [67]) use multiple threads to execute program codes...fault detection, such as EDDI [35], SWIFT [44], SRMT [60], DAFT [67], and Shoestring [12], all require program source code for recompilation, and cannot

The Aetiology of Gastric Cancer: the inhibition of the formation of N-nitroso compounds

NARCIS (Netherlands)

Zondervan K; Bueno de Mesquita HB; CCM

1994-01-01

Tot voor kort was bij diegenen die aan kanker overleden maagkanker de belangrijkste doodsoorzaak, echter sinds de tweede wereldoorlog dalen in de gehele wereld de sterfte cijfers voor maagkanker. Er worden twee typen maagkanker onderscheiden, het diffuse en het intestinale type. Het ontstaan van

Virtual reality in het onderwijs, hoe reëel is dat?

NARCIS (Netherlands)

Westera, Wim

2017-01-01

VR-technologie is onstuitbaar in opkomst. De prijzen dalen en de consumentenmarkt staat op doorbreken. Nu onderwijspioniers zich enthousiast op nieuwe VR-toepassingen voor leren en onderwijzen storten, rijst de vraag hoe we de educatieve potentie van VR moeten beoordelen: wordt het onderwijs beter,

De optimale datum voor het afsluiten van een lening

NARCIS (Netherlands)

van Ommeren, Bernard; Allers, Maarten; Vellekoop, Michel

Wie een lening moet afsluiten kan dat direct doen, of afwachten in de hoop dat de rente zal dalen vóór het moment dat de lening echt nodig is. Maar als de rente niet daalt maar stijgt, wordt de lening duurder. Dus wat is wijsheid?

Plucked String on a Shoestring Budget

Science.gov (United States)

Gluck, Paul

2009-01-01

The physics of the plucked string has been treated in many articles and books. For our 12th-grade high school physics laboratory, we have built a cheap, simple sonometer apparatus for each pair of students on which they may investigate some interesting phenomena that arise when a string is plucked. Among these are the generation of harmonics…

To the Moon on a Shoestring

Science.gov (United States)

Mortensen, T. F.; Rasmussen, S.

2013-09-01

The Euroluna Team is one of the around 30 teams competing in the Google Lunar X PRIZE Competition. The goal of the competition is to be the first team to successfully land a vehicle on the Moon, drive 500 m, and send video of the drive back to Earth. The Euroluna Team was formed in 2007, and the first flight hardware was acquired in 2010. Euroluna is financed privately with small funds. We have not received any external financial support. Therefore we have made an effort to keep all investments low. This has resulted in a design that uses new technologies and old technologies in a new way. Components are largely based on the Cubesat family and an ion thruster is being used for propulsion. A special strategy for landing on the Moon is under development. Special software of own design is being used for simulation of trajectories and energy consumption.

The business of iOS app development for iPhone, iPad and iPod Touch

CERN Document Server

Wooldridge, Dave

2014-01-01

Updated and expanded for the new Apple iOS8, The Business of iOS App Development, Third Edition shows you how to incorporate marketing and business savvy into every aspect of the design and development process, giving your app the best possible chance of succeeding in the App Store. This book is written by experienced developers with business backgrounds, taking you step-by-step through cost-effective marketing techniques that have proven successful for professional iOS app creators-perfect for independent developers on shoestring budgets. No prior business knowledge is required. The pheno

Author: L Hawthorne

African Journals Online (AJOL)

10332324

cooperation with" / "plus". It is submitted that according to Brand J inequality of bargaining power is not sufficient on its own to sustain a finding that a particular term of a contract is contrary to public policy and thus unenforceable. Consequently, to define "public policy" another element is required to supplement the inequality ...

Annual trace-metal load estimates and flow-weighted concentrations of cadmium, lead, and zinc in the Spokane River basin, Idaho and Washington, 1999-2004

Science.gov (United States)

Donato, Mary M.

2006-01-01

Streamflow and trace-metal concentration data collected at 10 locations in the Spokane River basin of northern Idaho and eastern Washington during 1999-2004 were used as input for the U.S. Geological Survey software, LOADEST, to estimate annual loads and mean flow-weighted concentrations of total and dissolved cadmium, lead, and zinc. Cadmium composed less than 1 percent of the total metal load at all stations; lead constituted from 6 to 42 percent of the total load at stations upstream from Coeur d'Alene Lake and from 2 to 4 percent at stations downstream of the lake. Zinc composed more than 90 percent of the total metal load at 6 of the 10 stations examined in this study. Trace-metal loads were lowest at the station on Pine Creek below Amy Gulch, where the mean annual total cadmium load for 1999-2004 was 39 kilograms per year (kg/yr), the mean estimated total lead load was about 1,700 kg/yr, and the mean annual total zinc load was 14,000 kg/yr. The trace-metal loads at stations on North Fork Coeur d'Alene River at Enaville, Ninemile Creek, and Canyon Creek also were relatively low. Trace-metal loads were highest at the station at Coeur d'Alene River near Harrison. The mean annual total cadmium load was 3,400 kg/yr, the mean total lead load was 240,000 kg/yr, and the mean total zinc load was 510,000 kg/yr for 1999-2004. Trace-metal loads at the station at South Fork Coeur d'Alene River near Pinehurst and the three stations on the Spokane River downstream of Coeur d'Alene Lake also were relatively high. Differences in metal loads, particularly lead, between stations upstream and downstream of Coeur d'Alene Lake likely are due to trapping and retention of metals in lakebed sediments. LOADEST software was used to estimate loads for water years 1999-2001 for many of the same sites discussed in this report. Overall, results from this study and those from a previous study are in good agreement. Observed differences between the two studies are attributable to streamflow

COMPARISON OF APATITE II™ TREATMENT SYSTEM AT TWO MINES FOR METALS REMOVAL

Science.gov (United States)

Two abandoned lead-zinc mine sites, the Nevada Stewart Mine (NSM) and Success Mine, are located within the Coeur d'Alene Mining District, in northern Idaho. An Apatite II™ Treatment System (ATS) was implemented at each site to treat metal-laden water, mainly zinc. In the ATS, f...

Science World Journal - Vol 4, No 4 (2009)

African Journals Online (AJOL)

Synergy Between Moringa oleifera Seed Powder And Alum In The Purification of Domestic Water · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. MB Dalen, JS Pam, A Izang, R Ekele. http://dx.doi.org/10.4314/swj.v4i4.51400 ...

Minder BPM, meer auto's? Stated preference onderzoek naar het effect van de omzetting van de BPM in de kilometerprijs op autobezit

NARCIS (Netherlands)

de Jong, Gerard; Kouwenhoven, Marco; Geurs, Karst Teunis

2010-01-01

Het kabinet Balkenende IV had vergevorderde plannen om in de periode 2013-2018 de belastingen op het aanschaffen en bezitten van auto’s om te zetten in een heffing op weggebruik (kilometerprijs). Dit zou de prijzen van auto’s in Nederland met maximaal 30% doen dalen. Er is relatief weinig onderzoek

Saline-water intrusion related to well construction in Lee County, Florida

Science.gov (United States)

Boggess, Durward Hoye; Missimer, T.M.; O'Donnell, T. H.

1977-01-01

Ground water is the principle source of water supply in Lee County, Florida where an estimated 30,000 wells have been drilled since 1990. These wells ranges in depth from about 10 to 1,240 feet and tap the water table aquifer or one or more of the artesian water-bearing units or zones in the Tamiami Formation, the upper part of the Hawthorn Formation, the lower part of the Hawthorn Formation and the Tampa Limestone and the Suwannee Limestone. Before 1968, nearly all wells were constructed with galvanized or black iron pipe. Many of these wells are sources of saline-water intrusion into freshwater-bearing zones. The water-bearing zones in the lower part of the Hawthorn Formation, Tampa Limestone, and Suwannee Limestone are artesian-they have higher water levels and usually contain water with a higher concentration of dissolved solids than do the aquifers occurring at shallower depths. The water from these deeper aquifers generally range in dissolved solids concentration from about 1,500 to 2,400 mg/L, and in chloride from about 500 to 1,00 mg/L. A maximum chloride concentration of 15,200 mg/L has been determined. Few of the 3,00 wells estimated to have been drilled to these zones contain sufficient casing to prevent upward flow into overlaying water-bearing zones. Because of water-level differentials, upward movement and lateral intrusion of saline water occurs principally into the upper part of the Hawthorn Formation where the chloride concentrations in water unaffected by saline-water intrusion ranges from about 80 to 150 mg/L. Where intrusion from deep artesian zones has occurred, the chloride concentration in water from the upper part of the Hawthorn Formation ranges from about 300 to more than 2,100 mg/L Surface discharges of the saline water from wells tapping the lower part of the Hawthorn Formation and the Suwannee Limestone also had affected the water-table aquifer which normally contains water with 10 to 50 mg/L of chloride. In one area, the chloride

Restaurering af Skjern Å

DEFF Research Database (Denmark)

Jessen, K.; Boysen Larsen, B.; Bundgaard, P.

Denne rapport indeholder resultaterne af den natur- og miljøovervågning, der blev iværksat som en del af naturgenopretningen af Skjern Å 1999-2002. Ved projektet ophørte den kunstige afvanding af den vestlige del af Skjern Å dalen. Størstedelen af de dyrkede arealer ændredes til ekstensive græsni...

The Radio JOVE Project - Shoestring Radio Astronomy

Science.gov (United States)

Thieman, J.; Flagg, R.; Greenman, W.; Higgins, C.; Reyes, F.; Sky, J.

2010-01-01

Radio JOVE is an education and outreach project intended to give students and other interested individuals hands-on experience in learning radio astronomy. They can do this through building a radio telescope from a relatively inexpensive kit that includes the parts for a receiver and an antenna as well as software for a computer chart recorder emulator (Radio Skypipe) and other reference materials

Creative market development : marketing on a shoestring

International Nuclear Information System (INIS)

McLeod, D.

2004-01-01

The initiatives that led to the development, construction and financing of Toronto's wind turbine by the Toronto Renewable Energy Co-op (TREC) were outlined in this PowerPoint presentation. The initiative for this first urban-based turbine in North America stemmed from a lack of green power in Ontario's energy market and a strong push from the public for more green power. TREC researched a variety of potential wind tower sites in Toronto and submitted a pre-feasibility report. The construction of the wind turbine involved a joint venture between WindShare and Toronto Hydro Energy Services. The basic principals behind co-operative financing were reviewed along with the challenges of marketing the project

Hanging on a Shoestring: Cameroon's Democratisation Process ...

African Journals Online (AJOL)

Pour les bénéficiaires [du système], il engendre un changement dans la culture politique. Les perdants optent pour la sortie. A cause de cette situation le Cameroun est une faible, plutôt qu'une forte démocratie. Quand bien même seule cette dernière permettrait une consolidation démocratique, il est argumenté que ceci a ...

Improvised Apparatus: A Lab on a Shoestring.

Science.gov (United States)

Bullen, T. G.

1983-01-01

Discusses the construction of various types of physics equipment from laboratory "bits and pieces" (parts of discarded/unusable equipment). Includes comments on constructing improvised equipment from similar bits and pieces in schools in Peru and the Caribbean. (JN)

Marketing Education on a Shoestring: A Model.

Science.gov (United States)

Shreeve, William; And Others

Few educators envision themselves as marketing or public relations experts, yet economic reality is forcing many academicians into these roles. Over the past four years, the Eastern Washington University Department of Education has developed a successful marketing model for educators. The model begins with a successful reform of department…

Structure/Property Relationships of Siloxane-Based Liquid Crystalline Materials

Science.gov (United States)

1992-05-01

1974). (6) Goossens , N.J.,., Mol. Cryst. Liq. Cryst., 12,237-244(1971). (7) Gray, G.W. and Goodby, J.W.G., Smectic Liquid Crystals- Textures and...pp 30-105, (1989). 42 (59) Richards , R.D.C., Hawthorne, W.D., Hill, J.S., White, M.S., Lacey, D., Semlyen, J.A., Gray, G.W., and Kendrick, T.C., J...946(1985). (30) Davidson, P. and Levelut, A.M., J. Phys., 49, 689-695(1988). (31) Richards , R.D.C., Hawthorne, W.D., Hill, J.S., White, M.S., Lacey

OXIDATIVE STABILITY OF CHILLED CHICKEN MEAT AFTER FEEDING OF SELECTED PLANTS

Directory of Open Access Journals (Sweden)

Mária Martonová

2010-07-01

Full Text Available  The effect of feeding of lemon balm (Melissa officinalis, L and combination of yarrow (Achillea millefolium L and hawthorn (Crataegus oxyacantha L on oxidative stability and sensory properties of produced poultry meat was investigated. Sixty one-day-old commercial broiler chicks (ROSS 308 were used in our experiment, divided into 3 groups, and fed 41 days, as follows: control (K was fed with standard diet without supplementation of plants; second group (M was fed with standard diet supplemented with grounded lemon balm in concentration 2 % per 1 kg; and third group was fed with standard diet supplemented with grounded yarrow (2 % and hawthorn (1 %. Results showed that supplementation with lemon balm, and mainly combination of yarrow and hawthorn in the diet significantly caused reduction of lipid oxidation processes in thigh meat during chilling storage of samples. In addition, supplementation of plants in the diet had positive effect on sensory quality of meat of broiler chickens.    doi:10.5219/38 

[Crataegus oxyacantha (aubepine) in the use as herb medicine in France].

Science.gov (United States)

Ju, Li-Ya

2005-04-01

Crataegus oxyacantha (Aubepine, Hawthorn), was used by european herbalist in the first century A. D. It went out fashion as a medicine until the 19th century for heart disease. The leaves, flowers, and berries of hawthorn contain a variety of bioflavonoid-like complexes that appear to be primarily responsible for the cardiac actions of the plant. Bioflavonoids found in C. oxyacantha include oligomeric procyanidins (OPCc), vitexin, quercetin, and hyperoside. The action of these compounds on the cardiovascular system has led to the development of leaf and flower extracts. As described in French pharmacopea, the hyperoside is the marker for quality control.

[Efficacy and safety of a herbal drug containing hawthorn berries and D-camphor in hypotension and orthostatic circulatory disorders/results of a retrospective epidemiologic cohort study].

Science.gov (United States)

Hempel, Bernd; Kroll, Michael; Schneider, Berthold

2005-01-01

Korodin Herz-Kreislauf-Tropfen, a herbal drug containing D-camphor (CAS 76-22-2; 2.5 %) and a liquid extract of fresh hawthorn berries (97.3%), has been used since many years for the treatment of orthostatic hypotension. The combination as well as its constituents were tested in clinical trials against placebo with healthy volunteers and patients using tilt-tests. The objective of this study was to investigate efficacy and safety of the drug under the conditions of medical practice in comparison to other drugs admitted for this indication. The study was performed as an epidemiological retrospective cohort study in 46 medical practices in Germany. In the practices the files were reviewed for patients who were treated between 1st January 2000 and 31st December 2002 for orthostatic hypotension. Included in the study were all patients who were treated either with the test drug or a control drug containing etilefrine, oxilofrine, midodrine, norfenefrine or dihydroergotamine and who met the inclusion criteria. The data of the files were coded, transferred to case report forms and augmented by the physician's statements about symptoms and success. Effect criteria were the improvement of symptoms and change of blood pressure during treatment. The correctness of the data was controlled using anonymous copies of the files. A total of 490 patients (399 in the test-group and 91 in the control group) between 11 and 102 years were included in the study. To correct heterogeneities in baseline conditions, treatment results were adjusted by regression and stratification to equal baseline conditions using the propensity score. The adjusted odds ratio for improvement was 5.6, the adjusted mean increase of the systolic blood pressure the 2-fold compared to the control group. The difference was highly significant and did not depend on age or initial blood pressure. In the test group two adverse events were observed which had no relation to the medication; in the control group one

Starting a Planned Maintenance Program on a Shoestring

Science.gov (United States)

Adams, Matt

2013-01-01

This article addresses two of the most repeated questions in APPA (1) How can we convert our reactive maintenance operations to a planned and predictable operation? and (2) In addition, how can we do this with little or no additional resources? It seems reasonable to assume that if a department is short on resources and in a full-blown reactive…

Lead content of roadside fruit and berries

Energy Technology Data Exchange (ETDEWEB)

Fowles, G W.A.

1976-01-01

Blackberries, elderberries, hawthorn berries, holly berries and rose hips have been examined for their lead content, which has been shown to be directly related to the proximity of the growing fruit and berries to roads, the traffic density and the time of exposure. The maximum levels found (in ppm for undried fruit and berries) were blackberries 0.85, elderberries 6.77, hawthorn berries 23.8, holly berries 3.5 and rose hips 1.45. Very thorough washing with water removed 40-60% of the lead from heavily contaminated fruit and berries. When elderberries were used for winemaking over 60% of the lead was extracted and remained in solution in the wine. 25 references, 4 tables.

The Combination of Catechin and Epicatechin Gallate from Fructus Crataegi Potentiates β-Lactam Antibiotics Against Methicillin-Resistant Staphylococcus aureus (MRSA in Vitro and in Vivo

Directory of Open Access Journals (Sweden)

Jiang Zheng

2013-01-01

Full Text Available Fructus crataegi (hawthorn is the common name of all plant species in the genus Crataegus of the Rosaceae family. In the present study, three monomers of (+-catechin (C, (−-epicatechin gallate (ECg and (−-epigallocatechin (EGC were isolated from the hawthorn under the guide of antibacterial sensitization activity. The bioactivity of the composite fraction in enhancing the antibacterial effect of oxacillin against methicillin-resistant Staphylococcus aureus (MRSA was greater than that of the individual monomer of the hawthorn extract in vitro. Two-fold dilution and checkerboard methods were used to analyze antibacterial activity and screen for the combination and proportion of monomers with the best bioactivity. The result showed that C (128 mg/L combined with ECg (16 mg/L had the greatest effect and the combination also reduced the bacterial load in blood of septic mice challenged with a sublethal dose of MRSA, increased daunomycin accumulation within MRSA and down-regulated the mRNA expression of norA, norC and abcA, three important efflux pumps of MRSA. In summary, C and ECg enhanced the antibacterial effect of β-lactam antibiotics against MRSA in vitro and in vivo, which might be related to the increased accumulation of antibiotics within MRSA via suppression of important efflux pumps’ gene expression.

A generalized genetic framework for the development of sinkholes and Karst in Florida, U.S.A.

Science.gov (United States)

Beck, Barry F.

1986-03-01

Karst topography in Florida is developed on the Tertiary limestones of the Floridan aquifer Post-depositional diagenesis and solution have made these limestones highly permeable, T=ca. 50,000 m2/d. Zones of megaporosity have formed at unconformities, and dissolution has enlarged joints and fractures Erosion of the overlying clastic Miocene Hawthorn group strata on one flank of a structural arch has exposed the limestone The elevated edge of the Hawthorn cover forms the Cody scarp Ubiquitous solution pipes have previously formed at joint intersections and are now filled Downwashing of the fill deeper into solution cavities in the limestone and subsidence of the overlying unconsolidated sediments causes surface collapse a subsidence doline or sinkhole This process may penetrate up to 60 m of the semi-consolidated Hawthorn cover, as occurred when the Winter Park sinkhole developed Dense clusters of solution pipes may have formed cenotes which are now found on the exposed limestone terrain Groundwater moves laterally as diffuse flow except where input or outflow is concentrated. At sinking streams, vertical shafts, and springs, karst caves have formed, but only the major sinking streams form through-flowing conduit systems Shaft recharge dissipates diffusely. Spring discharge is concentrated from diffuse flow In both cases, conduits taper and merge into a zone of megaporosity

Mining-induced seismicity at the Lucky Friday Mine: Seismic events of magnitude >2.5, 1989--1994

Energy Technology Data Exchange (ETDEWEB)

Whyatt, J.K.; Williams, T.J. [USDOE, Spokane, WA (United States). Spokane Research Center; Blake, W. [Blake (W.), Hayden Lake, ID (United States); Sprenke, K. [Idaho Univ., Moscow, ID (United States); Wideman, C. [Montana Tech, Butte, MT (United States)

1996-09-01

An understanding of the types of seismic events that occur in a deep mine provides a foundation for assessing the seismic characteristics of these events and the degree to which initiation of these events can be anticipated or controlled. This study is a first step toward developing such an understanding of seismic events generated by mining in the Coeur d`Alene Mining District of northern Idaho. It is based on information developed in the course of a long-standing rock burst research effort undertaken by the U. S. Bureau of Mines in cooperation with Coeur d`Alene Mining District mines and regional universities. This information was collected for 39 seismic events with local magnitudes greater than 2.5 that occurred between 1989 and 1994. One of these events occurred, on average, every 8 weeks during the study period. Five major types of characteristic events were developed from the data; these five types describe all but two of the 39 events that were studied. The most common types of events occurred, on average, once every 30 weeks. The characteristic mechanisms, first-motion patterns, damage patterns, and relationships to mining and major geologic structures were defined for each type of event. These five types of events need to be studied further to assess their ability to camouflage clandestine nuclear tests as well as the degree to which they can be anticipated and controlled.

Monitoring of Erwinia amylovora in Montenegro

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Dragana Radunović

2015-09-01

Full Text Available Recent studies of Erwinia amylovora in Montenegro, conducted from 2012 to 2014, indicated that the bacterium was widespread in the northern, continental part of the country, where the most important fruit-growing regions are situated. The presence of the bacterium was confirmed on quince, pear, apple, medlar and hawthorn. Pathogenic, cultural and biochemical characteristics of E. amylovora strains sampled from pome fruit species and indigenous flora in Montenegro had been studied previously. In the present study, serological tests were used for identification of E. amylovora strains originating from pome fruit trees and indigenous plants. Monitoring of E. amylovora and collection of samples with symptoms of bacterial fire blight from different hosts and locations were performed in Montenegro from 2012 to 2014. Isolation of the bacterium on nutrient medium produced a large number of isolates, whose pathogenicity was confirmed on immature pear fruits. Twenty-seven strains of the bacterium, originating from three pome fruit species (quince, pear and apple and one indigenous species (hawthorn were selected for serological analyses. Two applied serological methods, ELISA and IF test, enabled rapid detection of the bacterium and simultaneous examination of a large number of samples over a short period of time. Serological analyses showed high homogeneity in antigenic structure of the studied E. amylovora strains sampled from quince, pear, apple and hawthorn from nine locations in Montenegro.

Creolising Political Identity and Social Scientific Method

African Journals Online (AJOL)

2014-06-16

Jun 16, 2014 ... When accepting the 2013 Latin American and Caribbean Regional ..... of theory emerging from Native or Latin America, the Caribbean, and .... Turner, Victor, 1969, The Ritual Process: Structure and Anti-Structure, Hawthorne,.

Sobre urnas griegas y pompas de jabón: transformaciones de la ecfrasis en La casa de los siete tejados

Directory of Open Access Journals (Sweden)

Patricia Simonson

2015-05-01

Full Text Available El artículo lleva a cabo un doble ejercicio de literatura comparada: por un lado, explora el papel del arte visual en la organización narrativa de La casa de los siete tejados, de Nathaniel Hawthorne; por otro, examina la manera en que Hawthorne “recicla” el uso que hace John Keats de una ecfrasis inestable en “Oda sobre una urna griega” (donde el poeta inglés medita sobre la noción problemática de inmortalidad artística, y sobre el estatus del poeta moderno frente a los antiguos para plantear una reflexión propiamente norteamericana sobre el oficio del artista en su sociedad y sobre su propia relación con el canon europeo y con el público estadounidense. 

Rudolf Steiner Farm School, Hawthorne Valley.

Science.gov (United States)

Rudolf Steiner Farm School, Harlemville, Ghent, NY.

The goal of the Rudolf Steiner Farm School (which employs the spiritual/scientific path of knowledge described by Rudolf Steiner in the early 1900's) is to awaken and cultivate the capacities of the full human being through education, the arts, and agriculture, in direct relationship with nature, the spiritual universe, and current times. The…

Facility Focus: Food Service.

Science.gov (United States)

College Planning & Management, 2002

2002-01-01

Describes the Hawthorn Court Community Center at Iowa State University, Ames, and the HUB-Robeson Center at Pennsylvania State University. Focuses on the food service offered in these new student-life buildings. Includes photographs. (EV)

Elton Mayo and Carl Rogers: A Tale of Two Techniques.

Science.gov (United States)

Mahoney, Kevin T.; Baker, David B.

2002-01-01

Compares the simultaneous emergence of Mayo's nonauthoritarian interviewing approach and Rogers' nondirective counseling approach. Examines the influence of Piaget on Mayo and reviews the Hawthorne studies. Concludes that differences in the approaches outweigh similarities. (Contains 21 references.) (SK)

A Regional Guidebook for Conducting Functional Assessments of Forested Wetlands in the Arkansas Valley Region of Arkansas

Science.gov (United States)

2008-08-01

the Piedmont of the Carolinas and Georgia. EPA/600/R-96/057, U.S. Environ- mental Protection Agency National Health and Environmental Effects...Cornus florida green ash Fraxinus pennsylvanica hawthorn Crataegus spp. hibiscus Hibiscus spp. highbush blueberry Vaccinium arboreum honey locust

Science on a Shoestring: Building Nursing Knowledge With Limited Funding.

Science.gov (United States)

Conn, Vicki S; Topp, Robert; Dunn, Susan L; Hopp, Lisa; Jadack, Rosemary; Jansen, Debra A; Jefferson, Urmeka T; Moch, Susan Diemert

2015-10-01

Building the science for nursing practice has never been more important. However, shrunken federal and state research budgets mean that investigators must find alternative sources of financial support and develop projects that are less costly to carry out. New investigators often build beginning programs of research with limited funding. This article provides an overview of some cost-effective research approaches and gives suggestions for finding other sources of funding. Examples of more cost-effective research approaches include adding complementary questions to existing funded research projects; conducting primary analysis of electronic patient records and social media content; conducting secondary analysis of data from completed studies; reviewing and synthesizing previously completed research; implementing community-based participatory research; participating in collaborative research efforts such as inter-campus team research, practice-based research networks (PBRNs), and involving undergraduate and doctoral students in research efforts. Instead of relying on funding from the National Institutes of Health (NIH) and other government agencies, nurse researchers may be able to find support for research from local sources such as businesses, organizations, or clinical agencies. Investigators will increasingly have to rely on these and other creative approaches to fund and implement their research programs if granting agency budgets do not significantly expand. © The Author(s) 2015.

Near-infrared Spectroscopy as a Process Analytical Technology Tool for Monitoring the Parching Process of Traditional Chinese Medicine Based on Two Kinds of Chemical Indicators.

Science.gov (United States)

Li, Kaiyue; Wang, Weiying; Liu, Yanping; Jiang, Su; Huang, Guo; Ye, Liming

2017-01-01

The active ingredients and thus pharmacological efficacy of traditional Chinese medicine (TCM) at different degrees of parching process vary greatly. Near-infrared spectroscopy (NIR) was used to develop a new method for rapid online analysis of TCM parching process, using two kinds of chemical indicators (5-(hydroxymethyl) furfural [5-HMF] content and 420 nm absorbance) as reference values which were obviously observed and changed in most TCM parching process. Three representative TCMs, Areca ( Areca catechu L.), Malt ( Hordeum Vulgare L.), and Hawthorn ( Crataegus pinnatifida Bge.), were used in this study. With partial least squares regression, calibration models of NIR were generated based on two kinds of reference values, i.e. 5-HMF contents measured by high-performance liquid chromatography (HPLC) and 420 nm absorbance measured by ultraviolet-visible spectroscopy (UV/Vis), respectively. In the optimized models for 5-HMF, the root mean square errors of prediction (RMSEP) for Areca, Malt, and Hawthorn was 0.0192, 0.0301, and 0.2600 and correlation coefficients ( R cal ) were 99.86%, 99.88%, and 99.88%, respectively. Moreover, in the optimized models using 420 nm absorbance as reference values, the RMSEP for Areca, Malt, and Hawthorn was 0.0229, 0.0096, and 0.0409 and R cal were 99.69%, 99.81%, and 99.62%, respectively. NIR models with 5-HMF content and 420 nm absorbance as reference values can rapidly and effectively identify three kinds of TCM in different parching processes. This method has great promise to replace current subjective color judgment and time-consuming HPLC or UV/Vis methods and is suitable for rapid online analysis and quality control in TCM industrial manufacturing process. Near-infrared spectroscopy.(NIR) was used to develop a new method for online analysis of traditional Chinese medicine.(TCM) parching processCalibration and validation models of Areca, Malt, and Hawthorn were generated by partial least squares regression using 5

The U.S. Combat Aircraft Industry 1909-2000. Structure Competition Innovation

Science.gov (United States)

2003-01-01

assistant secretary of Defense; and Alain Enthoven, also of RAND, who became a deputy assistant secretary of Defense and helped establish the new Defense...Fred, Northrop: An Aeronautical History, Hawthorne, Calif.: Northrop Corporation, 1976. Anderton , David A., Republic F-105 Thunderchief, London

Pollination biology of fruit-bearing hedgerow plants and the role of flower-visiting insects in fruit-set.

Science.gov (United States)

Jacobs, Jennifer H; Clark, Suzanne J; Denholm, Ian; Goulson, Dave; Stoate, Chris; Osborne, Juliet L

2009-12-01

In the UK, the flowers of fruit-bearing hedgerow plants provide a succession of pollen and nectar for flower-visiting insects for much of the year. The fruits of hedgerow plants are a source of winter food for frugivorous birds on farmland. It is unclear whether recent declines in pollinator populations are likely to threaten fruit-set and hence food supply for birds. The present study investigates the pollination biology of five common hedgerow plants: blackthorn (Prunus spinosa), hawthorn (Crataegus monogyna), dog rose (Rosa canina), bramble (Rubus fruticosus) and ivy (Hedera helix). The requirement for insect pollination was investigated initially by excluding insects from flowers by using mesh bags and comparing immature and mature fruit-set with those of open-pollinated flowers. Those plants that showed a requirement for insect pollination were then tested to compare fruit-set under two additional pollination service scenarios: (1) reduced pollination, with insects excluded from flowers bagged for part of the flowering period, and (2) supplemental pollination, with flowers hand cross-pollinated to test for pollen limitation. The proportions of flowers setting fruit in blackthorn, hawthorn and ivy were significantly reduced when insects were excluded from flowers by using mesh bags, whereas fruit-set in bramble and dog rose were unaffected. Restricting the exposure of flowers to pollinators had no significant effect on fruit-set. However, blackthorn and hawthorn were found to be pollen-limited, suggesting that the pollination service was inadequate in the study area. Ensuring strong populations of insect pollinators may be essential to guarantee a winter fruit supply for birds in UK hedgerows.

Antipsychotic treatment dosing profile in patients with schizophrenia evaluated with electronic monitoring (MEMS®).

Science.gov (United States)

Acosta, Francisco J; Ramallo-Fariña, Yolanda; Bosch, Esperanza; Mayans, Teresa; Rodríguez, Carlos J; Caravaca, Ana

2013-05-01

Although the Medication Event Monitoring System (MEMS®) device offers accurate information on treatment dosing profile, such profile has never been studied in patients with schizophrenia. Enhancing our knowledge on this issue would help in developing intervention strategies to improve adherence to antipsychotic treatment in these patients. 74 outpatients with schizophrenia were monitored with the MEMS device for a 3-month period, for evaluation of antipsychotic treatment dosing profile, possible influence of medication schedule-related variables, adherence to treatment--considering dose intake within prescribed timeframes--and possible Hawthorne's effect of using the MEMS device. Dose-omission gaps occurred in 18.7% of monitoring days, most frequently during weekends, almost significantly. Almost one-third of prescribed doses were taken out of prescribed time. Neither the prescribed number of daily doses nor the indicated time of the day for dose intake (breakfast, dinner), were associated with correct antipsychotic dosing. Excess-dose was rare in general, and more frequent out of prescribed dose timeframe. No Hawthorne's effect was found for the MEMS device. Adherence reached only 35% according to a definition that included dose intake within prescribed timeframes. Antipsychotic treatment dosing was considerably irregular among patients with schizophrenia. Strategies to reduce dose-omission gaps and increase dosing within prescribed timeframes seem to be necessary. Gaining knowledge on precise oral antipsychotic dosing profiles or the influence of schedule-related variables may be useful to design strategies towards enhancing adherence. There appears to be no Hawthorne's effect associated with the use of MEMS devices in outpatients with schizophrenia. Copyright © 2013 Elsevier B.V. All rights reserved.

Amateur Telescope Making

Science.gov (United States)

Tonkin, Stephen

Many amateur astronomers make their own instruments, either because of financial considerations or because they are just interested. Amateur Telescope Making offers a variety of designs for telescopes, mounts and drives which are suitable for the home-constructor. The designs range from simple to advanced, but all are within the range of a moderately well-equipped home workshop. The book not only tells the reader what he can construct, but also what it is sensible to construct given what time is available commercially. Thus each chapter begins with reasons for undertaking the project, then looks at theoretical consideration before finishing with practical instructions and advice. An indication is given as to the skills required for the various projects. Appendices list reputable sources of (mail order) materials and components. The telescopes and mounts range from "shoestring" (very cheap) instruments to specialist devices that are unavailable commercially.

Oor referensie en (tersyde oor representasie

Directory of Open Access Journals (Sweden)

H. Viljoen

1990-05-01

Full Text Available This article attempts to define the notion of representation by means of a critique of the reception of the film Fiela se kind (Fiela’s child, based on the novel with the same name by Dalene Matthee. It shows how historical facts become subjected to different norms within the fictional space of the novel (and the film and how the meaning of both is not primarily dependent on the correspondence to historical reality, but is influenced by filmic and novelistic coding, the horizon of expectations of the audience and the social symbolic value of certain places like the farmhouse.

Assessing the extent and effects of herbicide drift into Danish hedgerows

DEFF Research Database (Denmark)

Bruus, M.; Strandberg, M. T.; Andersen, H. V.

Very low dosages of herbicides are known to cause effects on bird cherry (Prunus avium) and hawthorn (Crataegus monogyna). With the purpose of studying whether this is a general phenomenon two other common hedgerow species, Sambucus nigra (elder) and Sorbus intermedia (Swedish whitebeam), were...

78 FR 9725 - Endangered Species; Receipt of Applications for Permit

Science.gov (United States)

2013-02-11

...-66682A The applicant requests a permit to re-export a captive-born male Asian elephant (Elephas maximus... species (Mescocapromys species), African elephant (Loxodonta Africana), Asian elephant (Elephas maximus... covers activities to be conducted by the applicant over a 5-year period Applicant: Hawthorn Corporation...

Foundations of Job Satisfaction in the Media Industries.

Science.gov (United States)

DeFleur, Margaret H.

1992-01-01

Examines classic sources on job satisfaction, including Adam Smith, Karl Marx, and the Hawthorne studies. Studies the job satisfaction of 1,526 mass communication graduates and compares satisfaction levels across the 9 different media fields. Finds a clear hierarchy of satisfaction within the nine fields. (SR)

78 FR 23252 - Ocean Transportation Intermediary License Applicants

Science.gov (United States)

2013-04-18

.... Logistics, Inc. dba BE Logistics dba Belogistics dba Core Logistics (NVO), 12911 Simms Avenue, Hawthorn, CA... (QI), Kevin L. Miller, Secretary, Application Type: QI Change Triple Eagle Logistics Inc. dba Triple Eagle Logistic Canada Inc. (NVO & OFF), 17890 Castleton Street, Suite 367, City of Industry, CA 91748...

Field Demonstration/Validation of Electrolytic Barriers for Energetic Compounds at Pueblo Chemical Depot

Science.gov (United States)

2010-01-01

measuring the intensity of fluorescence at 517 nm using an Ocean Optics USB-2000TM spectrometer and an Ocean OpticsTM custom six-around-one fiber ...Umatilla Army Depot, OR Demilitarization (washout) Basalt Deep (>50 feet) NRC (2005) Installation Action Plan for UAAP March 2001 Hawthorne

Polyphenolic Composition of Crataegus monogyna Jacq.: From Chemistry to Medical Applications

Directory of Open Access Journals (Sweden)

Seyed Fazel Nabavi

2015-09-01

Full Text Available The abundance of scientific evidence has shown that many synthetic drugs can cause serious adverse effects in patients. Recently, the search of natural therapeutic agents with low adverse effects has attracted much attention. In particular, considerable interest has focused on edible and medicinal plants, which play an important role in human diet, and have been used for disease treatment since ancient times. Crataegus monogyna Jacq. (hawthorn is one of the most important edible plants of the Rosaceae family and is also used in traditional medicine. Growing evidence has shown that this plant has various interesting physiological and pharmacological activities due to the presence of different bioactive natural compounds. In addition, scientific evidence suggests that the toxicity of hawthorn is negligible. Therefore, the aim of this paper is to provide a critical review of the available scientific literature about pharmacological activities as well as botanical aspects, phytochemistry and clinical impacts of C. monogyna.

77 FR 65151 - Finding of Substantial Inadequacy of Implementation Plan; Call for California State...

Science.gov (United States)

2012-10-25

... for submitting comments. Email: tax[email protected] . Mail or deliver: Wienke Tax, Air Planning Office... INFORMATION CONTACT: Wienke Tax, Air Planning Office, U.S. Environmental Protection Agency, Region 9, Mail Code AIR-2, 75 Hawthorne Street, San Francisco, California 94105-3901, 415-947-4192, tax[email protected

76 FR 48002 - Approval and Promulgation of Air Quality Implementation Plans; State of California; Interstate...

Science.gov (United States)

2011-08-08

... things, adequate measures prohibiting emissions of air pollutants in amounts which will interfere with...://www.regulations.gov and in hard copy at EPA Region IX, 75 Hawthorne Street, San Francisco, California... only at the hard copy location (e.g., copyrighted material) and some may not be available in either...

Human Relations-skolen

DEFF Research Database (Denmark)

Scheuer, Steen

2014-01-01

, men også arbejdssociologien, arbejdspsykologien og human resource development. Den første retning udsprang af de såkaldte Hawthorne-eksperimenter og psykologen Elton Mayos bearbejdelse af resultaterne derfra. Den anden er en løsere gruppering bestående af navne som Abraham Maslow og Frederick Herzberg...

Impact of observing hand hygiene in practice and research: a methodological reconsideration.

Science.gov (United States)

Gould, D J; Creedon, S; Jeanes, A; Drey, N S; Chudleigh, J; Moralejo, D

2017-02-01

The purpose of hand hygiene is to break the chain of healthcare-associated infection. In many countries hand hygiene is regularly audited as part of quality assurance based on recommendations from the World Health Organization. Direct observation is the recommended audit method but is associated with disadvantages, including potential for being observed to alter usual behaviour. The Hawthorne effect in relation to hand hygiene is analogous with productivity improvement by increasing the frequency with which hand hygiene is undertaken. Unobtrusive and/or frequent observation to accustom staff to the presence of observers is considered an acceptable way of reducing the Hawthorne effect, but few publications have discussed how to implement these techniques or examine their effectiveness. There is evidence that awareness of being watched can disrupt the usual behaviour of individuals in complex and unpredictable ways other than simple productivity effect. In the presence of auditors, health workers might defer or avoid activities that require hand hygiene, but these issues are not addressed in guidelines for practice or research studies. This oversight has implications for the validity of hand hygiene audit findings. Measuring hand hygiene product use overcomes avoidance tactics. It is cheaper and generates data continuously to assess the compliance of all clinicians without disrupting patient care. Disadvantages are the risk of overestimating uptake through spillage, wastage, or use by visitors and non-clinical staff entering patient care areas. Electronic devices may overcome the Hawthorne and avoidance effects but are costly and are not widely used outside research studies. Copyright © 2016 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Lead toxicosis in tundra swans near a mining and smelting complex in northern Idaho

Science.gov (United States)

Blus, L.J.; Henny, C.J.; Hoffman, D.J.; Grove, R.A.

1991-01-01

Die-offs of waterfowl have occurred in the Coeur d`Alene River system in northern Idaho since at least the early 1900`s. We investigated causes of mortality and lead and cadmium contamination of 46 tundra swans (Cygnus columbianus) from 1987 to 1989; an additional 22 swans found dead in 1990 were not examined. We necropsied 43 of the 46 birds found from 1987 to 1989; 38 of these were from the Coeur d`Alene River system, which has been contaminated with mining and smelting wastes for a century, and the other 5 were from a nearby, relatively uncontaminated area. Of the 36 livers of swans from the contaminated area that were analyzed, 32 contained lethal levels of lead (6 to 40 micrograms/g, wet weight) and all birds exhibited several symptoms of lead poisoning, notably enlarged gall bladders containing viscous, darkgreen bile. Only 13% of the lead-poisoned birds (10% when data were included from other studies of swans in the area) contained shot, compared to 95% of lead-poisoning swans in studies outside northern Idaho. Lead concentrations in blood samples from 16 apparently healthy swans (0.5 to 2.3 micrograms/g, and 4 leadpoisoned birds found moribund (1.3 to 9.6 micrograms/g) indicating that tundra swans accumulated high levels of lead from ingestion of sediment that contained up to 8,700 micrograms/g of lead and plants that contained up to 400 micrograms/g. The swans spend only a few weeks in the area staging during the spring migration. The five tundra swans from the uncontaminated area had low levels of lead and essentially no symptoms of lead poisoning.(ABSTRACT TRUNCATED AT 250 WORDS)

Incidence of viruses in highbush blueberry (Vaccinium corymbosum L. in Serbia

Directory of Open Access Journals (Sweden)

Jevremović Darko

2016-01-01

Full Text Available A large-scale survey for highbush blueberry (Vaccinium corymbosum L. viruses in Serbia was performed from 2011 to 2015. A total of 81 leaf samples from 15 locations were collected and analyzed for the presence of 8 viruses. Serological ELISA assay was performed to determine the presence of: Blueberry scorch virus (BlScV, Blueberry shock virus (BlShV, Blueberry shoestring virus (BSSV, Blueberry leaf mottle virus (BLMoV, Tobacco ringspot virus (TRSV and Tomato ringspot virus (ToRSV. All samples were tested for the presence of Blueberry red ringspot virus (BRRV by PCR and for Blueberry mosaic-associated virus (BlMaV by RT-PCR test. The analyses confirmed the presence of BlMaV in 8 (9.9% samples and BRRV in 1 (1.2% sample. No BlScV, BlShV, BLMoV, BSSV, TRSV or ToRSV viruses were detected in any of the analyzed samples.

Status report of the energy amplifier concept

CERN Document Server

Rubbia, Carlo

1997-01-01

We report the main results of study performed at CERN over the last three years by few people and with shoe-string funding on the potential impact of new Accelerators technologies in the field of Energy production from nuclei. Accelerators have been universal tools to nuclear reactions : why not using them to produce practical, sizeable amounts of nuclear transmutations, i.e. to: 1. eliminate unwanted long-lived, radioactive Waste from LWR's; 2. (eventually to produce energy in non-critical conditions, similar to the promises of Fusion and 3. as a substitution of Reactors for the neutron activation of short-lived radioactive elements for industrial and medical applications. - We have studied at the CERN-PS both the energy (heat) produced in nuclear cascades in a sub-critical environment (k=0.90) and the transmutation of unwanted waste in a small lethargy, transparent medium (lead). These experiments have been driven by conceptual studies and elaborate computer simulations of nuclear cascades and extend the we...

The New Scarlet Letter: Student Perceptions of the Accounting Profession after Enron

Science.gov (United States)

Coleman, Mimi; Kreuze, Jerry; Langsam, Sheldon

2004-01-01

Recent scandals have tarnished the integrity of the accounting profession, marking it with a modern version of the scarlet letter "A," which represented disgrace in Nathaniel Hawthorne's "The Scarlet Letter." In this study, the authors surveyed college business students on their perceptions of the accounting profession and examined how it can…

The DARPA High-Performance Polymer Program. Volume 2. Appendix--Selected Presentation Material From the Program Review Held on 14-15 January 1992

Science.gov (United States)

1992-09-01

Deex Zero Corp. August 3 Frank Allan EM Industries, Hawthorne, NY August 17 Dr. Kazutami Sakamoto Ajinomoto Co., Teaneck, NJ August 25 Dr. David Casasent...Sakamoto Ajinomoto , Teaneck, NJ Dr. K. Yamada Dr. T. Takahashi June 14 Dr. Hundi P. Kamath Raychem Corp., Menlo Park, CA Dr. Stephen Moore Dr. Phil

78 FR 77780 - Qualification of Drivers; Exemption Applications; Vision

Science.gov (United States)

2013-12-24

...), Stephen R. Marshall (MS), Edgar H. Meraz (NM), Ralph Reno (NJ), Glennis R. Reynolds (KY), Joseph B... Thomas (PA), Clifford B. Thompson, Jr. (SC), Donald L. Urmston (OH), Steven M. Veloz (CA), Stephen H...), James L. Hawthorne (TX), Johnny D. Ivey (NC), Darryl H. Johnson (WV), David Jones (FL), Thomas L...

Hypnotherapy and Test Anxiety: Two Cognitive-Behavioral Constructs. The Effects of Hypnosis in Reducing Test Anxiety and Improving Academic Achievement in College Students.

Science.gov (United States)

Sapp, Marty

A two-group randomized multivariate analysis of covariance (MANCOVA) was used to investigate the effects of cognitive-behavioral hypnosis in reducing test anxiety and improving academic performance in comparison to a Hawthorne control group. Subjects were enrolled in a rigorous introductory psychology course which covered an entire text in one…

Ocoee Junior High School's Total School Reading Program on a Shoestring.

Science.gov (United States)

Hinson, Bess; Williams, Robert W.

The total school reading program described in this booklet includes a program for remedial, developmental, and special education students. Faculty members and students not participating in this program spend one half hour a day in a silent reading program. The booklet outlines each facet of the program, lists the equipment and materials used,…

Incremental Risks of Transporting NARM to the LLW Disposal Facility at Hanford

International Nuclear Information System (INIS)

Weiner, R.F.

1999-01-01

This study models the incremental radiological risk of transporting NARM to the Hanford commercial LLW facility, both for incident-free transportation and for possible transportation accidents, compared with the radiological risk of transporting LLW to that facility. Transportation routes are modeled using HIGHWAY 3.1 and risks are modeled using RADTRAN 4. Both annual population doses and risks, and annual average individual doses and risks are reported. Three routes to the Hanford site were modeled from Albany, OR, from Coeur d'Alene, ID (called the Spokane route), and from Seattle, WA. Conservative estimates are used in the RADTRAN inputs, and RADTRAN itself is conservative

Biennial Guidance Test Symposium (15th) Held in Holloman Air Force Base, New Mexico on 24-26 September 1991. Volume 1

Science.gov (United States)

1991-09-01

H., D. E. Olsen , and L. J. Levy, "Estimation and Tests of Hypothesis for the Initial Mean and Covariance -in the Kalman Filter Model...KENNETH R. 6585TH TEST GROUP/GD HOLLOMAN AP1 NM HC21 SELMER R. NORTHROP OPERATIONS HAWTHORNE CA HOLMES DONALD W. ROCKWELL ANAHEIM CA HOLSAPPLE BOYD E

PROSE FICTION--SHORT STORY, NOVEL. LITERATURE CURRICULUM V, TEACHER AND STUDENT VERSIONS.

Science.gov (United States)

KITZHABER, ALBERT R.

THE BASIC CONVENTIONS THAT SHAPE THE CREATION OF THE SHORT STORY AND THE NOVEL ARE EXAMINED IN THIS 11TH-GRADE LITERATURE UNIT. THE SECTION ON THE SHORT STORY ILLUSTRATES NARRATIVE FICTION FORM THROUGH THE SHORT STORIES OF FORSTER, JACKSON, STEINBECK, THURBER, POE, MCCULLERS, HAWTHORNE, MANSFIELD, SALINGER, STEELE, AND COLLIER. EMPHASIZED IN EACH…

Pilot Test of Hot Gas Decontamination of Explosives-Contaminated Equipment at Hawthorne Army Ammunition Plant (HWAAP), Hawthorne, Nevada. Appendices. Revision

Science.gov (United States)

1990-06-01

The data reduction is performed as follows: 7.7.2.1 Average the area responses of each standard and calculate relative standard deviations. 7.7.2.2...from the analyses are on the chronatogram and on the data sheet. Tha data reduction Is performed as follows: 7.7.4.1 Sum the areas of peaks in the...with PlastUce YJa. Journal of the American IndustrIl4 Hygiene AUocioion. .?S.19i-297. 1i44. 3. BurrelU Manual for tis Analysts. Sev. enth editiaoq

Age, stress, and isolation in older adults living with HIV.

Science.gov (United States)

Webel, Allison R; Longenecker, Chris T; Gripshover, Barbara; Hanson, Jan E; Schmotzer, Brian J; Salata, Robert A

2014-01-01

People living with HIV (PLWH) have increasingly longer life spans. This age group faces different challenges than younger PLWH, which may include increased stress and social isolation. The purpose of this study was to determine whether the age and sex of PLWH are associated with measures of physiologic stress, perceived stress, and social isolation. In this cross-sectional study, we enrolled 102 PLWH equally into four groups divided by age (younger or older than 50 years) and gender. Participants completed well-validated survey measurements of stress and isolation, and their heart rate variability over 60 minutes was measured by Holter monitor. The mean (SD) Perceived Stress Scale score was 17.4 (6.94), mean Visual Analog Stress Scale score was 3.51 (2.79), and mean Hawthorne Friendship Scale score, a measure of social isolation, was 17.03 (4.84). Mean heart rate variability expressed as the SD of successive N-N intervals was 65.47 (31.16) msec. In multivariable regression models that controlled for selected demographic variables, there was no relationship between the Perceived Stress Scale and age (coefficient = -0.09, p =-0.23) or female gender (coefficient = -0.12, p = 0.93); however, there was a modest relationship between female gender and stress using the Visual Analog Stress Scale (coefficient = 1.24, p = 0.05). Perceived Stress was negatively associated with the Hawthorne Friendship score (coefficient = -0.34, p = 0.05). Hawthorne Friendship score was positively associated with younger age (coefficient = 0.11, p = 0.02). Age was the only independent predictor of physiologic stress as measured by heart rate variability (coefficient = -1.3, p age-related changes in heart rate variability do not appear to be related to perceived stress or social isolation. Future longitudinal research is required to more thoroughly understand this relationship and its impact on the health of PLWH.

Hand-in Hand, Building Community on Common Ground

Science.gov (United States)

Lawton, Pamela Harris

2010-01-01

Shortly after the author began teaching at the University of North Carolina at Charlotte (UNCC), Frances Hawthorne, one of the studio faculty, approached her to work on a community-based art project with students. Frances is a social justice artist who works collaboratively with marginalized groups such as the homeless and inmates at the…

EPR study on non- and gamma-irradiated herbal pills

Energy Technology Data Exchange (ETDEWEB)

Aleksieva, K., E-mail: katerina_bas@abv.b [Institute of Catalysis, Bulgarian Academy of Sciences, 1113 Sofia (Bulgaria); Lagunov, O. [Institute of Catalysis, Bulgarian Academy of Sciences, 1113 Sofia (Bulgaria); Dimov, K. [Institute of Cryobiology and Food Technologies, 1162 Sofia (Bulgaria); Yordanov, N.D. [Institute of Catalysis, Bulgarian Academy of Sciences, 1113 Sofia (Bulgaria)

2011-06-15

The results of EPR studies on herbal pills of marigold, hawthorn, yarrow, common balm, tutsan, nettle and thyme before and after gamma-irradiation are reported. Before irradiation all samples exhibit one weak singlet EPR line with a g-factor of 2.0048{+-}0.0005. After irradiation herbal pills could be separated in two groups according to their EPR spectra. Radiation-induced free radicals in pills of marigold, yarrow, nettle, tutsan and thyme could be attributed mainly to saccharide excipients. Tablets of hawthorn and common balm show 'cellulose-like' EPR spectrum, superimposed on partly resolved carbohydrate spectrum, due to the active part (herb) and inulin, which is present in the pills as an excipient. Fading study of the radiation-induced EPR signals confirms that sugar radicals are more stable than cellulose species. The reported results show that the presence of characteristic EPR spectra of herbal pills due to excipients or active part can be used as unambiguous proof of radiation processing within 35 or more days after irradiation.

Crataegus special extract WS 1442: up-to-date review of experimental and clinical experiences.

Science.gov (United States)

Zorniak, M; Szydlo, B; Krzeminski, T F

2017-08-01

Extracts and tinctures made from Crataegus spp. (Hawthorn) have been used as cardioprotective remedies since ancient times. WS 1442 special extract, manufactured by Dr. W. Schwabe Pharmaceuticals©, made from Crataegus spp. Leaves and flowers is one of the most studied and popular of preparations received from Hawthorn. It is integral, and most important active component of such herbal drugs as Crataegutt® novo 450, and CardioMax®. This standardized extract contains 18.75% oligomeric procyanidins (OPC), which have beneficial cardioprotective values and play a role as free-radicals scavengers, that protect the ischemic heart tissue from neutrophile elastase action successions. Moreover, WS 1442 also carries proven vasorelaxant activity, via affecting eNOS synthase, and prevents ischemic heart tissue swelling by influence on calcium signaling pathways, and thus detain hyperpermeability of endothelium. Actions of WS 1442 special extract were investigated in in vitro as well as in vivo studies including large clinical trials. In this review authors present current state of knowledge about possible beneficial effects of WS 1442 special extract on cardiovascular system.

EPR study on non- and gamma-irradiated herbal pills

International Nuclear Information System (INIS)

Aleksieva, K.; Lagunov, O.; Dimov, K.; Yordanov, N.D.

2011-01-01

The results of EPR studies on herbal pills of marigold, hawthorn, yarrow, common balm, tutsan, nettle and thyme before and after gamma-irradiation are reported. Before irradiation all samples exhibit one weak singlet EPR line with a g-factor of 2.0048±0.0005. After irradiation herbal pills could be separated in two groups according to their EPR spectra. Radiation-induced free radicals in pills of marigold, yarrow, nettle, tutsan and thyme could be attributed mainly to saccharide excipients. Tablets of hawthorn and common balm show 'cellulose-like' EPR spectrum, superimposed on partly resolved carbohydrate spectrum, due to the active part (herb) and inulin, which is present in the pills as an excipient. Fading study of the radiation-induced EPR signals confirms that sugar radicals are more stable than cellulose species. The reported results show that the presence of characteristic EPR spectra of herbal pills due to excipients or active part can be used as unambiguous proof of radiation processing within 35 or more days after irradiation.

EPR study on non- and gamma-irradiated herbal pills

Science.gov (United States)

Aleksieva, K.; Lagunov, O.; Dimov, K.; Yordanov, N. D.

2011-06-01

The results of EPR studies on herbal pills of marigold, hawthorn, yarrow, common balm, tutsan, nettle and thyme before and after gamma-irradiation are reported. Before irradiation all samples exhibit one weak singlet EPR line with a g-factor of 2.0048±0.0005. After irradiation herbal pills could be separated in two groups according to their EPR spectra. Radiation-induced free radicals in pills of marigold, yarrow, nettle, tutsan and thyme could be attributed mainly to saccharide excipients. Tablets of hawthorn and common balm show "cellulose-like" EPR spectrum, superimposed on partly resolved carbohydrate spectrum, due to the active part (herb) and inulin, which is present in the pills as an excipient. Fading study of the radiation-induced EPR signals confirms that sugar radicals are more stable than cellulose species. The reported results show that the presence of characteristic EPR spectra of herbal pills due to excipients or active part can be used as unambiguous proof of radiation processing within 35 or more days after irradiation.

"Paul Revere's Ride": Awakening Abolitionists

Science.gov (United States)

Lepore, Jill

2011-01-01

Henry Wadsworth Longfellow used to be both the best-known poet in the English-speaking world and the most beloved, adored by the learned and the lowly alike, read by everyone from Nathaniel Hawthorne and Abraham Lincoln to John Ruskin and Queen Victoria--and, just as avidly, by the queen's servants. "Paul Revere's Ride" is Longfellow's best-known…

Multimedia campaign on a shoestring: promoting 'Stay Active - Stay Independent' among seniors.

Science.gov (United States)

John-Leader, Franklin; Van Beurden, Eric; Barnett, Lisa; Hughes, Karen; Newman, Beth; Sternberg, Jason; Dietrich, Uta

2008-04-01

This paper describes a multimedia campaign implemented in rural New South Wales on a budget smaller than that typical of many published campaigns. The 'To Be Young at Heart - Stay Active Stay Independent' (SASI) campaign was one arm of a multi-strategic program to reduce falls among seniors by promoting physical activity. This 18-month campaign used social marketing techniques. Central to this campaign was strong formative research, significant use of corporate, community and media partnerships and a detailed, strategic distribution plan. Campaign reach was evaluated by a community intercept survey. A variety of high-quality information, education and communication (IEC) resources were developed. Overall, the campaign cost was calculated at USD 191,000. The actual cost of USD 42,000 (excluding staff time) was used to generate almost double this amount in sponsorship (USD 82,000). In the mid-campaign reach survey, 36% recognised the campaign and attributed this to television (58%), newspaper (33%), poster (13%) and bus-back advertising (8%). Of these respondents, 21% reported seeking information about physical activity, 33% reported increased intention to be more active, and 22% reported becoming more active as a result of the campaign. It is possible to develop and deliver a well-designed, multi-media campaign on a limited budget by using sound formative research and engaging community and corporate partners to generate sponsorship. An effective distribution strategy is crucial and may require additional partnerships at State or national level.

Running a network on a shoestring: the Global Invasive Species Information Network

Science.gov (United States)

Jarnevich, Catherine S.; Simpson, Annie; Graham, James J; Newman, Gregory J.; Bargeron, Chuck T.

2015-01-01

The Global Invasive Species Information Network (GISIN) was conceptualized in 2004 to aggregate and disseminate invasive species data in a standardized way. A decade later the GISIN community has implemented a data portal and three of six GISIN data aggregation models in the GISIN data exchange Protocol, including invasive species status information, resource URLs, and occurrence data. The portal is based on a protocol developed by representatives from 15 countries and 27 organizations of the global invasive species information management community. The GISIN has 19 data providers sharing 34,343 species status records, 1,693,073 occurrences, and 15,601 resource URLs. While the GISIN's goal is to be global, much of its data and funding are provided by the United States. Several initiatives use the GISIN as their information backbone, such as the Great Lakes Early Detection Network (GLEDN) and the North American Invasive Species Network (NAISN). Here we share several success stories and organizational challenges that remain.

Evaluation of Wildlife Mitigation Sites at the Chief Joseph Dam Project (1993/1994 Season)

Science.gov (United States)

1994-07-22

clematis RAMUALER. Ifr . Site COST Cormes stolonifera red-osier dogwood CORNACLAE P,, Iff Site CRCO Crataegus columbiana Columbia hawthorn RC)SACEAE R...firitillary __________ EiS, BE GAAR Galillardla aristata gaillardia COMPOSnAE ES, BE GAAP Galiwn aparine bedsmrw _____________ Irr. Site GABO Galium...spicalum bluebunch wheatgras GRAMINEAE BS, BB AG Agrotids sp bentgrass GRAMINEAE Ifr . Site, near shore AGIN Agroawis interrupta internited bentgrass

Sweetening syrup production by enzymatic hydrolysis of starch variety yam (Dioscorea rotundata

Directory of Open Access Journals (Sweden)

Carlos Ramón Vidal Tovar

2011-04-01

Full Text Available Sweeteners syrups produced by enzymatic hydrolysis from starch of hawthorn yam (Dioscorea rotundata. The starch was extracted by a scratched, washed, sedimented and drying; the yield was quantified taking into account the amount of initial raw material and was determined the concentration of starch, amylose, amylopectin, crude fiber, ash, protein, fat and humidity in accordance with the requirements of the AOAC standards, and ICONTEC COVENIN. Enzymatic hydrolysis of starch was conducted using ∂-amylase, glucoamylase and pullulanase in starch solutions at 36 and 46 % w/w varying the order of application of glucoamylase and pullulanase were determined pH, Brix, moisture, reducing sugars (AR, total sugar (TS and the dextrose equivalent (ED in the syrups obtained. In the liquefaction were obtained with an intermediate syrups sweeteners ED 18.81% and 22.15%. Syrups low and medium conversion with an ED between 34-45% in the first saccharification and high conversion syrups with a DE between 75-79% as a final product. The above values allow the use of hawthorn yam starch syrup production for multiple uses in different food industry processes.

Using Organizational Behavior To Increase the Efficiency of The Total Force Enterprise

Science.gov (United States)

2013-06-01

decentralization, and specialization of function or task.15 The neoclassical theory era started with the Hawthorne studies in 1927. A group of...discussed further in Chapter 3, theories of organizational behavior combined with models that help to affect change positively, can potentially mean...What this paper intends to solve, is how today’s formal and informal leaders can use the principles of organizational behavior theories and change

Performance of two bioswales on urban runoff management

Science.gov (United States)

Qingfu Xiao; E. McPherson; Qi Zhang; Xinlei Ge; Randy Dahlgren

2017-01-01

This study evaluated the effectiveness of two bioswales eight years after construction in Davis, California. The treatment bioswale measured 9 m × 1 m × 1 m (L × W × D). Engineered soil mix (75% native lava rock and 25% loam soil) replaced the native loam soil. Four Red Tip Photinia (Photinia × fraseri Dress) trees and two Blueberry Muffin Hawthorn...

Whole plant based treatment of hypercholesterolemia with Crataegus laevigata in a zebrafish model

Directory of Open Access Journals (Sweden)

Littleton Robert M

2012-07-01

Full Text Available Abstract Background Consumers are increasingly turning to plant-based complementary and alternative medicines to treat hypercholesterolemia. Many of these treatments are untested and their efficacy is unknown. This multitude of potential remedies necessitates a model system amenable to testing large numbers of organisms that maintains similarity to humans in both mode of drug administration and overall physiology. Here we develop the larval zebrafish (4–30 days post fertilization as a vertebrate model of dietary plant-based treatment of hypercholesterolemia and test the effects of Crataegus laevigata in this model. Methods Larval zebrafish were fed high cholesterol diets infused with fluorescent sterols and phytomedicines. Plants were ground with mortar and pestle into a fine powder before addition to food. Fluorescent sterols were utilized to optically quantify relative difference in intravascular cholesterol levels between groups of fish. We utilized the Zeiss 7-Live Duo high-speed confocal platform in order to both quantify intravascular sterol fluorescence and to capture video of the heart beat for determination of cardiac output. Results In this investigation we developed and utilized a larval zebrafish model to investigate dietary plant-based intervention of the pathophysiology of hypercholesterolemia. We found BODIPY-cholesterol effectively labels diet-introduced intravascular cholesterol levels (P t-test. We also established that zebrafish cardiac output declines as cholesterol dose increases (difference between 0.1% and 8% (w/w high cholesterol diet-treated cardiac output significant at P  Conclusions The results of this study demonstrate that the larval zebrafish has the potential to become a powerful model to test plant based dietary intervention of hypercholesterolemia. Using this model we have shown that hawthorn leaves and flowers have the potential to affect cardiac output as well as intravascular cholesterol levels

Archaeological Investigations of the Little Cypress Bayou Site (3CT50) Crittenden County, Arkansas. Volume 2 - Appendices

Science.gov (United States)

1986-01-01

RESULTS OF ANALYSES The analyses resulted in the identification of some 37 plant genus or species. Table 111-1 presents a complete listing of the...scientific and common names for all identified specimens. Certain of the materials could not be identified to either the genus or species level; these are...Chenopodium sp. Chenopod Crataegus sp. Hawthorn Curcurbita sp. Pumpkin or Squash Diospyros virginiana Persimmon Fabaceae Bean Family Fraxinus pennsylvanica

Report of the Materials Research Council (1975)

Science.gov (United States)

1975-10-01

into oil. Large feed lots in which cattle can be concentrated are expected to reduce beef costs significantly, but have not yet been constructed...second on Chemical Feed - stocks. By telephone it was agreed by the Steering Committee that small studies would be held on these topics. Hawthorne...relation to mechanical property characterization of fracture, creep , etc. Our purpose is to explore two related areas: I. Institutional Aspects of

Study of Navy Recruiting Simulation Tool

Science.gov (United States)

2010-03-01

can we begin to understand existing or emerging issues, start to build a foundation of knowledge, and help to set a course for future research. This...The goal of learning new skills is to ensure information is successfully transferred from short-term memory to long-term memory for future use. For...2010, from washingtontechnology.com: http://washingtontechnology.com/Articles/2003/12/12/ Elearning -technology-gets- smart.aspx 107 Hawthorne, D

Venture capital on a shoestring: Bioventures' pioneering life sciences fund in South Africa.

Science.gov (United States)

Masum, Hassan; Singer, Peter A

2010-12-13

Since 2000, R&D financing for global health has increased significantly, with innovative proposals for further increases. However, although venture capital (VC) funding has fostered life sciences businesses across the developed world, its application in the developing world and particularly in Africa is relatively new. Is VC feasible in the African context, to foster the development and application of local health innovation?As the most industrially advanced African nation, South Africa serves as a test case for life sciences venture funding. This paper analyzes Bioventures, the first VC company focused on life sciences investment in sub-Saharan Africa. The case study method was used to analyze the formation, operation, and investment support of Bioventures, and to suggest lessons for future health venture funds in Africa that aim to develop health-oriented innovations. The modest financial success of Bioventures in challenging circumstances has demonstrated a proof of concept that life sciences VC can work in the region. Beyond providing funds, support given to investees included board participation, contacts, and strategic services. Bioventures had to be proactive in finding and supporting good health R&D.Due to the fund's small size, overhead and management expenses were tightly constrained. Bioventures was at times unable to make follow-on investments, being forced instead to give up equity to raise additional capital, and to sell health investments earlier than might have been optimal. With the benefit of hindsight, the CFO of Bioventures felt that partnering with a larger fund might benefit similar future funds. Being better linked to market intelligence and other entrepreneurial investors was also seen as an unmet need. BioVentures has learned lessons about how the traditional VC model might evolve to tackle health challenges facing Africa, including how to raise funds and educate investors; how to select, value, and support investments; and how to understand the balance between financial and social returns. The experience of the fund suggests that future health funds targeting ailments of the poor might require investors that accept health benefits as part of their overall "return." Learning from Bioventures may help develop health innovation funding for sub-Saharan African that has combined health, financial, and economic development impacts.

Venture capital on a shoestring: Bioventures’ pioneering life sciences fund in South Africa

Directory of Open Access Journals (Sweden)

Singer Peter A

2010-12-01

Full Text Available Abstract Background Since 2000, R&D financing for global health has increased significantly, with innovative proposals for further increases. However, although venture capital (VC funding has fostered life sciences businesses across the developed world, its application in the developing world and particularly in Africa is relatively new. Is VC feasible in the African context, to foster the development and application of local health innovation? As the most industrially advanced African nation, South Africa serves as a test case for life sciences venture funding. This paper analyzes Bioventures, the first VC company focused on life sciences investment in sub-Saharan Africa. The case study method was used to analyze the formation, operation, and investment support of Bioventures, and to suggest lessons for future health venture funds in Africa that aim to develop health-oriented innovations. Discussion The modest financial success of Bioventures in challenging circumstances has demonstrated a proof of concept that life sciences VC can work in the region. Beyond providing funds, support given to investees included board participation, contacts, and strategic services. Bioventures had to be proactive in finding and supporting good health R&D. Due to the fund’s small size, overhead and management expenses were tightly constrained. Bioventures was at times unable to make follow-on investments, being forced instead to give up equity to raise additional capital, and to sell health investments earlier than might have been optimal. With the benefit of hindsight, the CFO of Bioventures felt that partnering with a larger fund might benefit similar future funds. Being better linked to market intelligence and other entrepreneurial investors was also seen as an unmet need. Summary BioVentures has learned lessons about how the traditional VC model might evolve to tackle health challenges facing Africa, including how to raise funds and educate investors; how to select, value, and support investments; and how to understand the balance between financial and social returns. The experience of the fund suggests that future health funds targeting ailments of the poor might require investors that accept health benefits as part of their overall “return.” Learning from Bioventures may help develop health innovation funding for sub-Saharan African that has combined health, financial, and economic development impacts.

Venture capital on a shoestring: Bioventures’ pioneering life sciences fund in South Africa

Science.gov (United States)

2010-01-01

Background Since 2000, R&D financing for global health has increased significantly, with innovative proposals for further increases. However, although venture capital (VC) funding has fostered life sciences businesses across the developed world, its application in the developing world and particularly in Africa is relatively new. Is VC feasible in the African context, to foster the development and application of local health innovation? As the most industrially advanced African nation, South Africa serves as a test case for life sciences venture funding. This paper analyzes Bioventures, the first VC company focused on life sciences investment in sub-Saharan Africa. The case study method was used to analyze the formation, operation, and investment support of Bioventures, and to suggest lessons for future health venture funds in Africa that aim to develop health-oriented innovations. Discussion The modest financial success of Bioventures in challenging circumstances has demonstrated a proof of concept that life sciences VC can work in the region. Beyond providing funds, support given to investees included board participation, contacts, and strategic services. Bioventures had to be proactive in finding and supporting good health R&D. Due to the fund’s small size, overhead and management expenses were tightly constrained. Bioventures was at times unable to make follow-on investments, being forced instead to give up equity to raise additional capital, and to sell health investments earlier than might have been optimal. With the benefit of hindsight, the CFO of Bioventures felt that partnering with a larger fund might benefit similar future funds. Being better linked to market intelligence and other entrepreneurial investors was also seen as an unmet need. Summary BioVentures has learned lessons about how the traditional VC model might evolve to tackle health challenges facing Africa, including how to raise funds and educate investors; how to select, value, and support investments; and how to understand the balance between financial and social returns. The experience of the fund suggests that future health funds targeting ailments of the poor might require investors that accept health benefits as part of their overall “return.” Learning from Bioventures may help develop health innovation funding for sub-Saharan African that has combined health, financial, and economic development impacts. PMID:21144079

Lead immobilization and phosphorus availability in phosphate-amended, mine-contaminated soils.

Science.gov (United States)

Osborne, Lydia R; Baker, Leslie L; Strawn, Daniel G

2015-01-01

Over a century of mining activities in the Coeur d'Alene mining district in Idaho have contaminated soils of the downstream basin with lead, arsenic, zinc, and cadmium. Elevated soil-Pb levels are a significant hazard to the health of humans and wildlife in the region. One in situ treatment approach for remediating Pb-contaminated soils is application of phosphorus to promote the formation of lead phosphate minerals that have low solubility. However, this remediation strategy may result in excess P runoff to surface waters, which can lead to eutrophication, particularly when used in riparian areas. Research presented in this paper describes experiments in which monopotassium phosphate (KHPO) solution was applied to two Pb-contaminated soils from the Coeur d'Alene River valley to determine how P loading rates affect both Pb immobilization and P mobility and to determine if an optimal P amendment rate can be predicted. Toxicity characteristic leaching procedure extractions were used to assess changes in Pb availability for uptake by an organism or mobilization through the soil, and Bray extractions were used to assess P availability for leaching out of the soil system. For the two soils tested, increasing phosphate amendment caused decreasing Pb extractability. Phosphorus amendment rates above approximately 70 mg kg, however, did not provide any additional Pb immobilization. Phosphorus availability increased with increasing phosphate application rate. An empirical relationship is presented that predicts extractable Pb as a function of extractable P. This relationship allows for prediction of the amount of Pb that can be immobilized at specified P leaching amounts, such as regulatory levels that have been established to minimize risks for surface water degradation. Results suggest that phosphate can be used to immobilize Pb in contaminated wetland or riparian areas without posing risks of P loading to surface waters. Copyright © by the American Society of Agronomy

The genetic basis for fruit odor discrimination in Rhagoletis flies and its significance for sympatric host shifts.

Science.gov (United States)

Dambroski, Hattie R; Linn, Charles; Berlocher, Stewart H; Forbes, Andrew A; Roelofs, Wendell; Feder, Jeffrey L

2005-09-01

Rhagoletis pomonella (Diptera: Tephritidae) use volatile compounds emitted from the surface of ripening fruit as important chemosensory cues for recognizing and distinguishing among alternative host plants. Host choice is of evolutionary significance in Rhagoletis because these flies mate on or near the fruit of their respective host plants. Differences in host choice based on fruit odor discrimination therefore result in differential mate choice and prezygotic reproductive isolation, facilitating sympatric speciation in the absence of geographic isolation. We test for a genetic basis for host fruit odor discrimination through an analysis of F2 and backcross hybrids constructed between apple-, hawthorn-, and flowering dogwood-infesting Rhagoletis flies. We recovered a significant proportion (30-65%) of parental apple, hawthorn, and dogwood fly response phenotypes in F2 hybrids, despite the general failure of F1 hybrids to reach odor source spheres. Segregation patterns in F2 and backcross hybrids suggest that only a modest number of allelic differences at a few loci may underlie host fruit odor discrimination. In addition, a strong bias was observed for F2 and backcross flies to orient to the natal fruit blend of their maternal grandmother, implying the existence of cytonuclear gene interactions. We explore the implications of our findings for the evolutionary dynamics of sympatric host race formation and speciation.

Use of Liquid Chromatography with Electrochemical Detection for the Determination of Antioxidants in Less Common Fruits

Directory of Open Access Journals (Sweden)

Zbynek Gazdik

2008-11-01

Full Text Available Neurodegenerative disorders (NDD have become the common global health burden over the last several decades. According to World Health Organization (WHO, a staggering 30 million people will be affected by Alzheimer’s disease in Europe and the USA by 2050. Effective therapies in this complex field considering the multitude of symptoms associated with NDD indications, have not been found yet. Based on the results of NDD related studies, prevention appears to be the promise alternative. Antioxidative and anti-inflammatory properties are hypothesized for natural phenolics, a group of plant secondary products that may positively impact neurodegenerative diseases. In these studies, phenolic-rich extracts from less common fruit species: Blue honeysuckle (Lonicera edulis, Turcz. ex. Freyn, Saskatoon berry (Amelanchier alnifolia Nutt., and Chinese hawthorn (Crateagus pinnatifida Bunge were obtained and analyzed to detect neuroprotective substances content and establish a potential therapeutic value. High performance liquid chromatography with electrochemical detection was optimized and further applied on analysis of the extracts of less common fruit species. It was observed that Chinese hawthorn and Blue honeysuckle extracts are potent source of neuroprotective phenolic antioxidants. In accordance the results, it appears that the fruit or formulated products may have the potential for the prevention of neurodegenerative diseases.

Therapeutic Strategy for Chronic Headache in Children

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H.O. Lezhenko

2016-05-01

Full Text Available The therapeutic efficacy of a combined homeopathic preparation Cefavora, which consists of alcoholic extracts of Ginkgo biloba, hawthorn (Crataegus and white mistletoe (Viscum album, has been studied in the treatment of chronic tension-type headache in children. It has been shown that alongside with elimination of headache manifestations, the use of homeopathic medicine has contributed to the normalization of adaptive mechanisms of autonomic regulation in children indicating its high therapeutic efficacy.

Post-Remediation Evaluation of EVO Treatment: How Can We Improve Performance

Science.gov (United States)

2017-11-15

QA/QC Quality Assurance/ Quality Control RAOs Remedial Action Objectives Resolutions Resolutions Consultants SA17 Study Area 17 viii SAP...upper 30 feet of the unconfined aquifer consists of fine sand with multiple discontinuous layers of silty sand , ranging from 1 to over 5 ft thick...Beneath the lower silty sand is a layer of fine to coarse grained sand that extends from 30 to 50 ft bgs. The confining unit of the Hawthorne Group

Non-traditional alternatives project for the control of dental biofilm alternative substances with antibacterial action for the disinfection of cavities

International Nuclear Information System (INIS)

Alfaro Mendez, Daniela; Correa Herrera, Graciela; Rivas Dona, Carmina

2013-01-01

The extracts of medicinal plants found in Costa Rica such as hawthorn, garlic and black tea were compared with Concepsis®, a product based on chlorhexidine used for the disinfection of dental cavities. The efficacy of the three plants was measured against S. mutans in in vitro cultures. Chlorhexidine has a higher bacteriostatic and bactericidal activity than the extracts of the three plants used, being the most effective agent against S. mutans [es

(σάρξ) en vyandskap (ἔχθρα)

African Journals Online (AJOL)

27 Aug 2015 ... The Spirit (πνεῦμα) and peace (εἰρήνη) with God as opposed to the Flesh (σάρξ) and ..... Porter 1993:696). Hierdie uitleg sluit nie uit dat εἰρήνη sou verwys na 'n toestand. 14.Vergelyk Romeine 5:1. 15.Kyk ook die verdere substansiëring ..... vyande van die kruis (Fil 3:18) (Hawthorne 2004:221–223).

A Critical Technical Review of Six Hazard Assessment Models

Science.gov (United States)

1975-12-01

temperature is 3000K. Vi The equation describing flame length is taken from a paper of Hawthorne, Weddell, and Hottel [3] who obtained the equation by...should be noted that the flame length given by equation (6.1) in AMSHAH is independent of the flow rate; flame length independence of flow rate does not...experiments and analyses upon which the formula for flame length is based are for jets issuing from circular orifices. Substantial departures from this

Vegetable ash as raw material in the production of glasses and enamels, for example the contemporary vegetable ashes from Burgundy, France

OpenAIRE

Colomban, Philippe; Tournié, Aurélie; De Montmollin, Frère Daniel; Krainhoefner, Frère Luc

2010-01-01

The powdery nature and high alkali content of vegetable ashes make them ideal raw materials to be used as modifiers of silicate compositions (glasses, enamels and ceramics). Their utilisation since ancient times is described in the literature of the history of glasses, but studies on the analyses of their composition are still limited. We discuss here the compositions of tree and shrub ashes (wattle, hawthorn, oak, green oak, olive wood, elm, poplar, apple tree, vine shoot), of plants (carex,...

The genus Crataegus L. in the western part of the buffer zone of the Low Tatras National Park (Slovakia, in accordance with recent morphological and systematic recognition

Directory of Open Access Journals (Sweden)

Ingrid Turisová

2013-04-01

Full Text Available The work contains results of investigation on the genus Crataegus L., conducted in 2011 ‑ 2012 on the area of the western part of the buffer zone of the Low Tatras National Park. Analysing various features, including the morphometric ones, occurrence of six native species, among them three species of hybrid origin, were confirmed in the investigated area. Comparative analysis of leaves morphology of the hybrid hawthorns and their original parental forms was carried out.

Visual Speed of Processing and Publically Observable Feedback in Video-Game Players

OpenAIRE

Patten, James William

2016-01-01

Time spent playing action-oriented video-games has been proposed to improve the functioning of visual attention and perception in a number of areas. These benefits are not always consistently reported, however. It was hypothesized that an improvement to visual Speed of Processing (SOP) in action-oriented Video-Game Players (VGPs) underlies many of the benefits of action video-game play, and furthermore the expression of this improvement was modulated by a Hawthorne effect (individuals behavin...

Long term performance of radon mitigation systems

International Nuclear Information System (INIS)

Prill, R.; Fisk, W.J.

2002-01-01

Researchers installed radon mitigation systems in 12 houses in Spokane, Washington and Coeur d'Alene, Idaho during the heating season 1985--1986 and continued to monitor indoor radon quarterly and annually for ten years. The mitigation systems included active sub-slab ventilation, basement over-pressurization, and crawlspace isolation and ventilation. The occupants reported various operational problems with these early mitigation systems. The long-term radon measurements were essential to track the effectiveness of the mitigation systems over time. All 12 homes were visited during the second year of the study, while a second set 5 homes was visited during the fifth year to determine the cause(s) of increased radon in the homes. During these visits, the mitigation systems were inspected and measurements of system performance were made. Maintenance and modifications were performed to improve system performance in these homes

Karst connections between unconfined aquifers and the Upper Floridan aquifer in south Georgia: geophysical evidence and hydrogeological models

Science.gov (United States)

Thieme, D. M.; Denizman, C.

2011-12-01

Buried karst features in sedimentary rocks of the south Georgia Coastal Plain present a challenge for hydrogeological models of recharge and confined flow within the underlying Upper Floridan aquifer. The Withlacoochee River, the trunk stream for the area, frequently disappears into subsurface caverns as it makes its way south to join the Suwannee River in northern Florida. The Withlacoochee also receives inputs from small ponds and bays which in turn receive spring and seep groundwater inputs. We have mapped karst topography at the "top of rock" using ground-penetrating radar (GPR). Up to seven meters of relief is indicated for the paleotopography on Miocene to Pliocene rocks, contrasting with the more subdued relief of the modern landscape. Current stratigraphic and hydrogeological reconstructions do not incorporate this amount of relief or lateral variation in the confining beds. One "pipe" which is approximately four meters in diameter is being mapped in detail. We have field evidence at this location for rapid movement of surficial pond and river water with a meteoric signature through several separate strata of sedimentary rock into an aquifer in the Hawthorn formation. We use our geophysical and hydrological field evidence to constrain quantitative hydrogeological models for the flow rates into and out of both this upper aquifer and the underlying Upper Floridan aquifer, which is generally considered to be confined by the clays of the Hawthorn.

Helicopter Controllability

Science.gov (United States)

1989-09-01

106 3. Program CC Systems Technology, Inc. (STI) of Hawthorne, CA., develops and markets PC control system analysis and design software including...is marketed in Palo Alto, Ca., by Applied i and can be used for both linear and non- linear control system analysis. Using TUTSIM involves developing...gravity centroid ( ucg ) can be calculated as 112 n m pi - 2 zi acg n i (7-5) where pi = poles zi = zeroes n = number of poles m = number of zeroes If K

Toxicity of lead-contaminated sediment to mute swans

Science.gov (United States)

Day, D.D.; Beyer, W.N.; Hoffman, D.J.; Morton, Alexandra; Sileo, L.; Audet, D.J.; Ottinger, M.A.

2003-01-01

Most ecotoxicological risk assessments of wildlife emphasize contaminant exposure through ingestion of food and water. However, the role of incidental ingestion of sediment-bound contaminants has not been adequately appreciated in these assessments. This study evaluates the toxicological consequences of contamination of sediments with metals from hard-rock mining and smelting activities. Lead-contaminated sediments collected from the Coeur d'Alene River Basin in Idaho were combined with either a commercial avian maintenance diet or ground rice and fed to captive mute swans (Cygnus olor) for 6 weeks. Experimental treatments consisted of maintenance or rice diets containing 0, 12 (no rice group), or 24% highly contaminated (3,950 ug/g lead) sediment or 24% reference (9.7 ug/g lead) sediment. Although none of the swans died, the group fed a rice diet containing 24% lead-contaminated sediment were the most severely affected, experiencing a 24% decrease in mean body weight, including three birds that became emaciated. All birds in this treatment group had nephrosis; abnormally dark, viscous bile; and significant (p < 0.05) reductions in hematocrit and hemoglobin concentrations compared to their pretreatment levels. This group also had the greatest mean concentrations of lead in blood (3.2 ug/g), brain (2.2 ug/g), and liver (8.5 ug/g). These birds had significant (alpha = 0.05) increases in mean plasma alanine aminotransferase activity, cholesterol, and uric acid concentrations and decreased plasma triglyceride concentrations compared to all other treatment groups. After 14 days of exposure, mean protoporphyrin concentrations increased substantially, and mean delta-aminolevulinic acid dehydratase activity decreased by more than 95% in all groups fed diets containing highly contaminated sediments. All swans fed diets that contained 24% lead-contaminated sediment had renal acid-fast intranuclear inclusion bodies, which are diagnostic of lead poisoning in waterfowl. Body

Assessing the extent and effects of herbicide drift into Danish hedgerows

DEFF Research Database (Denmark)

Pedersen, Marianne Bruus; Andersen, H. V.; Strandberg, M. T.

Very low dosages of herbicides are known to cause effects on bird cherry (Prunus avium) and hawthorn (Crataegus monogyna). It is not yet known whether other hedgerow trees and shrubs are equally sensitive to herbicide drift, to which extent spray drift into hedges and other habitats close to fiel...... were assessed. Metsulfuron methyl effects on Sambucus nigra (elder) and Sorbus intermedia were studied in separate experiments and will include second year effects. Methods and preliminary results are presented and discussed in relation to pesticide regulation....

Review of Facility Technology Options and their Development Status

Science.gov (United States)

1989-06-01

Manufacturers of Ice Storage Units Ice Storage Ton-Hours of Cooling Manufacturer Refrigeration Refrigeration Capacity Turbo Refrigeration Co. 625 - 25,000 7.5... disel fuel #2 and propane/LPG. PO Box 1757 jNG SS/W kW I TEPP" stands for Total Energy Media., PA 19063 NG 75175 kW IPOWr Rlant. First unit installed...CHO Gp500/ Hawthorne. CA cogeneration sets but Kawasakis AkashJi 673 Tokyo. Japan 400 kW Turbo Systems U S distr :utors do Telex: 5628951 International

Stunted sexuality in havvthorne's the blithedale romance Stunted sexuality in havvthorne's the blithedale romance

Directory of Open Access Journals (Sweden)

Arnold Gordenstein

2008-04-01

Full Text Available By now a commonplace of Blithedale Romance criticism is that Coverdale is a voyeur. But hardly anyone has related Coverdale's voyeurism to the larger psychological pattern that includes voyeurism and these to its central themes. Otto Fenichel couples voyeurism and toucheurism and defines them as "scoptophilia, the sexualization of the sensations of looking... analogous to touch eroticism." 1 Doubly restricted by Victorian morality as well as by his American Puritan heritage, Hawthorne indicated that the motivations that drew people to and that characterized their relationships at Blithedale were, in part, sexual. Since he could not directly describe this sexuality he used sight and touch images to convey the kind of attraction he had in mind. By now a commonplace of Blithedale Romance criticism is that Coverdale is a voyeur. But hardly anyone has related Coverdale's voyeurism to the larger psychological pattern that includes voyeurism and these to its central themes. Otto Fenichel couples voyeurism and toucheurism and defines them as "scoptophilia, the sexualization of the sensations of looking... analogous to touch eroticism." 1 Doubly restricted by Victorian morality as well as by his American Puritan heritage, Hawthorne indicated that the motivations that drew people to and that characterized their relationships at lithedale were, in part, sexual. Since he could not directly describe this sexuality he used sight and touch images to convey the kind of attraction he had in mind.

Dynamic pricing of electricity for residential customers. The evidence from Michigan

Energy Technology Data Exchange (ETDEWEB)

Faruqui, A.; Akaba, L. [The Brattle Group, 201 Mission Street, Suite 2800, San Francisco, CA 94105 (United States); Sergici, S. [The Brattle Group, 44 Brattle Street, Cambridge, MA 02138 (United States)

2013-08-15

The rollout of smart meters has enabled the provision of dynamic pricing to residential customers. However, doubts remain whether households can respond to time-varying price signals and that is preventing the full-scale rollout of dynamic pricing and the attainment of economic efficiency. Experiments are being conducted to test price responsiveness. We analyze data from a pilot in Michigan which featured two dynamic pricing rates and an enabling technology. Unlike most other pilots, it also included a group of 'information only' customers who were provided information on time-varying prices but billed on standard rates. Similarly, unlike most other pilots, it also included two control groups, one of whom knew they were in the pilot and one of whom did not. This was designed to test for the presence of a Hawthorne effect. Consistent with the large body of experimental literature, we find that customers, including low-income participants, do respond to dynamic pricing. We also find that the response to critical peak pricing rates is similar to the response to peak time rebates, consistent with the finding of one prior experiment but inconsistent with the finding of two prior experiments. We also find that the 'information only' customers respond to the provision of pricing information but at a substantially lower rate than the customers on dynamic pricing. We find that the response to enabling technology is muted. We do not find any evidence to suggest that a Hawthorne effect existed in this experiment.

Hand hygiene compliance rates: Fact or fiction?

Science.gov (United States)

McLaws, Mary-Louise; Kwok, Yen Lee Angela

2018-05-16

The mandatory national hand hygiene program requires Australian public hospitals to use direct human auditing to establish compliance rates. To establish the magnitude of the Hawthorne effect, we compared direct human audit rates with concurrent automated surveillance rates. A large tertiary Australian teaching hospital previously trialed automated surveillance while simultaneously performing mandatory human audits for 20 minutes daily on a medical and a surgical ward. Subtracting automated surveillance rates from human audit rates provided differences in percentage points (PPs) for each of the 3 quarterly reporting periods for 2014 and 2015. Direct human audit rates for the medical ward were inflated by an average of 55 PPs in 2014 and 64 PPs in 2015, 2.8-3.1 times higher than automated surveillance rates. The rates for the surgical ward were inflated by an average of 32 PPs in 2014 and 31 PPs in 2015, 1.6 times higher than automated surveillance rates. Over the 6 mandatory reporting quarters, human audits collected an average of 255 opportunities, whereas automation collected 578 times more data, averaging 147,308 opportunities per quarter. The magnitude of the Hawthorne effect on direct human auditing was not trivial and produced highly inflated compliance rates. Mandatory compliance necessitates accuracy that only automated surveillance can achieve, whereas daily hand hygiene ambassadors or reminder technology could harness clinicians' ability to hyperrespond to produce habitual compliance. Crown Copyright © 2018. Published by Elsevier Inc. All rights reserved.

Honeybees Increase Fruit Set in Native Plant Species Important for Wildlife Conservation

Science.gov (United States)

Cayuela, Luis; Ruiz-Arriaga, Sarah; Ozers, Christian P.

2011-11-01

Honeybee colonies are declining in some parts of the world. This may have important consequences for the pollination of crops and native plant species. In Spain, as in other parts of Europe, land abandonment has led to a decrease in the number of non professional beekeepers, which aggravates the problem of honeybee decline as a result of bee diseases In this study, we investigated the effects of honeybees on the pollination of three native plant species in northern Spain, namely wildcherry Prunus avium L., hawthorn Crataegus monogyna Jacq., and bilberry Vaccinium myrtillus L. We quantified fruit set of individuals from the target species along transects established from an apiary outwards. Half the samples were bagged in a nylon mesh to avoid insect pollination. Mixed-effects models were used to test the effect of distance to the apiary on fruit set in non-bagged samples. The results showed a negative significant effect of distance from the apiary on fruit set for hawthorn and bilberry, but no significant effects were detected for wildcherry. This suggests that the use of honeybees under traditional farming practices might be a good instrument to increase fruit production of some native plants. This may have important consequences for wildlife conservation, since fruits, and bilberries in particular, constitute an important feeding resource for endangered species, such as the brown bear Ursus arctos L. or the capercaillie Tetrao urogallus cantabricus L.

“We Must Get Rid of Slavery, or We Must Get Rid of Freedom.” Self, Other, and Emancipation in Antebellum America

Directory of Open Access Journals (Sweden)

Carrie Forsberg

2018-04-01

Full Text Available Antebellum American literature, like the country itself, was a heterogeny of Romanticism, Transcendentalism, and political prose culminating in the national narrative. Authors during this time struggled with the issue of slavery and their works reflected varying degrees of disdain for it and its treatment of slaves that were the direct representation of the Other. Prominent writers, including Ralph Waldo Emerson, Nathaniel Hawthorne, Herman Melville, and Walt Whitman used their prose and poetry to speak out about a nation cleaved in two. These two sides could not agree on how to move forward and this struggle was in fact a mirror image of the binary idea of the Self and the Other. If the Self was the white male, the Other was the slave or Native American who was outside of the antebellum norm. Emerson encouraged an equality and self-reliance that would reverse the power structure of the time. Hawthorne used veiled allegories to suggest that the nation´s slavery problem would rectify itself in time. Melville preached about capitalism and Christian hypocrisy while Whitman used his poetry to aesthetically envision a truly inclusive democratic antebellum America. These authors were pioneers in the humanism of literature that was meant to inspire the nation to achieve its potential and ensure that every voice would be heard. However, antebellum human rights were not fully realized and slavery dehumanized the Other leading to a nation divided and eventually civil war.

The Effect of Chlorides on the Correlation of Accelerated Laboratory Corrosion Tests to Out-Door Exposure Tests for Ceramics-Aluminum Couples

Science.gov (United States)

2010-02-01

approximately 2000 psi. (G-10 fiber glass) (G-10 fiber glass) Ceramic Coupon *Courtesy : George Hawthorn of Hawaii Corrosion Lab Outdoor Exposure Procedures...agricultural, and arid). • Hawaii’s climate is one of the most spatially diverse on Earth. Kahuku* Coconut Island* – Marine environment – Marine...T6 Al Kilauea Kahuku Coconut Island Manoa Campbell Waipahu Ewanui Mauna Loa C o rr o s io n r a te s a t th e i n te rf a c e r e g io n ( g m d

LONG-TERM DEMONSTRATION OF SORBENT ENHANCEMENT ADDITIVE TECHNOLOGY FOR MERCURY CONTROL

Energy Technology Data Exchange (ETDEWEB)

Jason D. Laumb; Dennis L. Laudal; Grant E. Dunham; John P. Kay; Christopher L. Martin; Jeffrey S. Thompson; Nicholas B. Lentz; Alexander Azenkeng; Kevin C. Galbreath; Lucinda L. Hamre

2011-05-27

Long-term demonstration tests of advanced sorbent enhancement additive (SEA) technologies have been completed at five coal-fired power plants. The targeted removal rate was 90% from baseline conditions at all five stations. The plants included Hawthorn Unit 5, Mill Creek Unit 4, San Miguel Unit 1, Centralia Unit 2, and Hoot Lake Unit 2. The materials tested included powdered activated carbon, treated carbon, scrubber additives, and SEAs. In only one case (San Miguel) was >90% removal not attainable. The reemission of mercury from the scrubber at this facility prevented >90% capture.

Probability and Statistics: 5 Questions

DEFF Research Database (Denmark)

Probability and Statistics: 5 Questions is a collection of short interviews based on 5 questions presented to some of the most influential and prominent scholars in probability and statistics. We hear their views on the fields, aims, scopes, the future direction of research and how their work fits...... in these respects. Interviews with Nick Bingham, Luc Bovens, Terrence L. Fine, Haim Gaifman, Donald Gillies, James Hawthorne, Carl Hoefer, James M. Joyce, Joseph B. Kadane Isaac Levi, D.H. Mellor, Patrick Suppes, Jan von Plato, Carl Wagner, Sandy Zabell...

Constitutive and herbivore-induced volatiles in pear, alder and hawthorn trees

NARCIS (Netherlands)

Scutareanu, P.; Bruin, de J.; Posthumus, M.A.; Drukker, B.

2003-01-01

Qualitative and quantitative differences among pear cultivars were found in constitutive and Cacopsylla-induced volatiles, depending on experimental treatment of the trees (i.e., uninfested and partly or completely infested by psyllids). Blend differences were also found between pear cultivars and

Congenital nystagmus and negative electroretinography

Directory of Open Access Journals (Sweden)

Roussi M

2011-04-01

Full Text Available Mirella Roussi, Hélène Dalens, Jean Jacques Marcellier, Franck BacinDepartment of Ophthalmology, Clermont-Ferrand University, Clermont-Ferrand, FranceAbstract: Congenital nystagmus is a pathologic oculomotor state appearing at about three to four months of age. The precise diagnosis requires detailed clinical examination and electrophysiological findings. This case report presents two male patients with congenital nystagmus examined longitudinally from the age of six months until 17-18 years of age. Clinical and electrophysiological protocols were detailed. The first results showed electronegative electroretinography in the two cases and examination combined with electroretinographic findings helped us to make the diagnosis of Congenital Night Stationary Blindness (CSNB. This diagnosis was confirmed by genetic studies. CSNB is interesting to study because through electrophysiological findings, it enables a better understanding of the physiology of neural transmission in the outer part of the retina.Keywords: Congenital nystagmus, negative electroretinography, congenital night stationary blindness

More attention for health due to air quality of particulates; Meer aandacht voor gezondheid door luchtkwaliteit van fijn stof

Energy Technology Data Exchange (ETDEWEB)

Keuken, M.; Voogt, M. [TNO, Apeldoorn (Netherlands); Van den Elshout, S. [DCMR Milieudienst Rijnmond, Rotterdam (Netherlands); De Jonge, D. [GGD amsterdam, Amsterdam (Netherlands)

2008-08-15

This article demonstrates that elementary carbon (EC) is a reliable indicator for soot concentrations in outdoor air and a better indicator for traffic emissions of particulate matter than PM10 and PM2.5. In Rotterdam, PM content remains at the same level, whereas concentrations of elementary carbon decrease steadily. The article recommends further study into which part of health effects ascribed to PM should actually be attributed to EC or for example to abrasion emissions, road dust blowing up and ultra fine particles. [mk]. [Dutch] In dit artikel wordt aangetoond dat elementair koolstof (EC) een goede indicator is voor roetconcentraties in de buitenlucht en een betere indicator voor verkeersuitstoot van fijn stof dan PM10 of PM2,5. In Rotterdam blijven PM-gehaltes op hetzelfde niveau, terwijl concentraties van elementair koolstof gestaag dalen. Het wordt aanbevolen te onderzoeken welk deel van de aan PM toegeschreven gezondheidseffecten in werkelijkheid aan EC is toe te schrijven of aan bijvoorbeeld slijtage-emissies, opwervelend wegenstof en ultrafijne deeltjes.

Electrochemical Determination of the Antioxidant Potential of Some Less Common Fruit Species

Directory of Open Access Journals (Sweden)

Boris Krska

2008-11-01

Full Text Available Various berries and fruit types of less common fruit species are known to contain antioxidants. Consumption of high amounts of antioxidant flavonoids, which display a variety of biological properties, including antiproliferative and anti-inflammatory activity, may have a positive impact on human health, particularly for the prevention of cancer and other inflammatory diseases. In these studies, based on the hypothesis that the fruit extract with the highest content would possess significantly higher health benefits, flavonoid-rich extracts were obtained from some less common fruit species – Blue Honeysuckles (Lonicera Kamtschatica and Lonicera edulis, Turcz. ex. Freyn, Saskatoon berry (Amelanchier alnifolia Nutt. and Chinese Hawthorn (Crataegus pinnatifida BUNGE – grown from germplasm held at the Mendel University of Agriculture and Forestry in Brno, Czech Republic and then characterized in terms of biological value based on the results from a relative antioxidant capacity assessment. The antioxidant content evaluation was based on the total flavonoid amount, determined by liquid chromatography with electrochemical detection (HPLC-ED. A DPPH• test was applied as a reference. The antioxidant content measured in Chinese Hawthorn fruit extract identified it as a potent source of flavonoid antioxidants, with a content 9-fold higher than that seen in Amelanchier fruit. The multifunctional HPLC-ED array method coupled with a DPPH• reference appears to be the optimal analytical progress, accurately reflecting the nutritivetherapeutic properties of a fruit.

Final Report: 8th International Symposium on Neutron Capture Therapy (NCT) for Cancer, May 15, 1998 - May 15, 1999

International Nuclear Information System (INIS)

Hawthorne, M.F.

1999-01-01

The 8th International Symposium on Neutron Capture Therapy for Cancer (8th ISNCTC) was held in La Jolla, CA on Sept. 13-18, 1998. This biennial meeting of the International Society for Neutron Capture Therapy (ISNCT) was hosted by Society President M.F. Hawthorne (UCLA Dept. of Chemistry and Biochemistry). The Symposium brought together scientists (300 registrants from 21 countries) from diverse fields to report the latest developments in NCT. Topics of the 275 papers presented (30 plenary lectures, 81 oral presentations, and 164 posters) included the physics of neutron sources, chemistry of tumor-targeting agents, dosimetry, radiobiological studies, and clinical applications

Contribution of flowering trees to urban atmospheric biogenic volatile organic compound emissions

Science.gov (United States)

Baghi, R.; Helmig, D.; Guenther, A.; Duhl, T.; Daly, R.

2012-10-01

Emissions of biogenic volatile organic compounds (BVOC) from urban trees during and after blooming were measured during spring and early summer 2009 in Boulder, Colorado. Air samples were collected onto solid adsorbent cartridges from branch enclosures on the tree species crabapple (Malus sp.), horse chestnut (Aesculus carnea, "Ft. McNair"), honey locust (Gleditsia triacanthos, "Sunburst"), and hawthorn (Crataegus laevigata, "Pauls Scarlet"). These species constitute ~ 65% of the insect-pollinated fraction of the flowering tree canopy (excluding catkin-producing trees) from the street area managed by the City of Boulder. Samples were analyzed for C10-C15 BVOC by thermal desorption and gas chromatography coupled to a flame ionization detector and a mass spectrometer (GC/FID/MS). Identified emissions and emission rates from these four tree species during the flowering phase were found to vary over a wide range. Monoterpene emissions were identified for honey locust, horse chestnut and hawthorn. Sesquiterpene emissions were observed in horse chestnut and hawthorn samples. Crabapple flowers were found to emit significant amounts of benzyl alcohol and benzaldehyde. Floral BVOC emissions increased with temperature, generally exhibiting exponential temperature dependence. Changes in BVOC speciation during and after the flowering period were observed for every tree studied. Emission rates were significantly higher during the blooming compared to the post-blooming state for crabapple and honey locust. The results were scaled to the dry mass of leaves and flowers contained in the enclosure. Only flower dry mass was accounted for crabapple emission rates as leaves appeared at the end of the flowering period. Total normalized (30 °C) monoterpene emissions from honey locust were higher during flowering (5.3 μgC g-1 h-1) than after flowering (1.2 μgC g-1 h-1). The total normalized BVOC emission rate from crabapple (93 μgC g-1 h-1) during the flowering period is of the same

Shoestring Digital Library: If Existing Digital Library Software Doesn't Suit Your Needs, Create Your Own

Science.gov (United States)

Weber, Jonathan

2006-01-01

Creating a digital library might seem like a task best left to a large research collection with a vast staff and generous budget. However, tools for successfully creating digital libraries are getting easier to use all the time. The explosion of people creating content for the web has led to the availability of many high-quality applications and…

Coming of Age on a Shoestring Budget: Financial Capability and Financial Behaviors of Lower-Income Millennials.

Science.gov (United States)

West, Stacia; Friedline, Terri

2016-10-01

Lower-income millennials make important financial decisions that may affect their future financial well-being. With limited resources, this population is at risk for acquiring too much debt or being unprepared for a financial emergency that can send them further into poverty and constrain their ability to leverage resources for future economic mobility. A financial capability approach, an intervention that combines financial education with financial inclusion through the use of a savings account, may correlate with millennials’ healthy financial behaviors. This study used data from the 2012 National Financial Capability Study to examine the relationship between financial capability and the financial behaviors of lower-income millennials between the ages of 18 and 34 years (N = 2,578). Compared with those lower-income millennials who were financially excluded, those who were financially capable were also 171 percent more likely to afford an unexpected expense, 182 percent more likely to save for emergencies, and 34 percent less likely to carry too much debt, relating to their greater overall financial satisfaction. The findings of this study indicate that interventions that develop lower-income millennials’ financial capability may be effective for promoting healthy financial behaviors.

Shoestrings and bricolage: some notes on researching the impact of a child's death on family relationships.

Science.gov (United States)

Riches, Gordon; Dawson, Pam

2002-04-01

An earlier version of this paper appeared as the appendix to our recent book, An Intimate Loneliness: Supporting Bereaved Parents and Children (G. Riches & P. Dawson, 2000). In it, we attempt to offer a brief history of the processes we have gone through in taking a simple research question, developing it into a practical proposal, experiencing how it shifted as we explored it, accounting for the changes that our broader reading imposed on our perceptions of what we were doing, and, finally, how the data itself and our efforts to understand it, resulted in a set of broad theoretical propositions rather than any tight conclusions.

Evaluation of antioxidant and antimicrobial activities of extract of Crataegus monogyna (hawthorn)

International Nuclear Information System (INIS)

Bouzid, W.; Yahia, M.; Abdeddaim, M.; Aberkane, M.C.; Ayachi, A.

2011-01-01

Various biological activities are attributed to a great variety of compounds isolated from natural plants. This study presents an attempt to evaluate the antimicrobial and antioxidant activity of organic and aqueous extract prepared from the edible part of Crataegus monogyna Jacq. Gualitative analysis of extracts by high performance liquid chromatography revealed the probable presence of quercetin in the EDm. The quantitative estimation of polyphenols (by the Folin-Ciocalteu method),total flavonoids (by the method of aluminium trichloride) and condensed tannins (by the method of iron trichloride) showed that the EDm and EMe extracts are richer in these compounds. The inhibition of couple oxidation of linoleic acid β-carotene was evaluated by the bleaching test of β-carotene, which showed a significant antioxidant activity for the EDm (48.46% inhibition) and EMe (36.40% inhibition). The evaluation of the antimicrobial potency of the extracts by the agar diffusion method showed that the extracts EEp EDm and EMe have an antibacterial activity on staphylococcus aureus strain at high concentration, whereas all extracts tested were inactive on Candida albicans. (author).

Ultra-pure, water-dispersed Au nanoparticles produced by femtosecond laser ablation and fragmentation

Directory of Open Access Journals (Sweden)

Kubiliūtė R

2013-07-01

Full Text Available Reda Kubiliūtė,1,2 Ksenia A Maximova,3 Alireza Lajevardipour,1 Jiawey Yong,1 Jennifer S Hartley,1 Abu SM Mohsin,1 Pierre Blandin,3 James WM Chon,1 Marc Sentis,3 Paul R Stoddart,1 Andrei Kabashin,3 Ričardas Rotomskis,2 Andrew HA Clayton,1,4 Saulius Juodkazis1,4 1Centre for Micro-Photonics and Industrial Research Institute Swinburne, Faculty of Engineering and Industrial Sciences Swinburne University of Technology, Hawthorn, VIC, Australia; 2Laboratory of Biomedical Physics, Vilnius University Institute of Oncology, Baublio, Vilnius, Lithuania; 3Aix-Marseille University, Centre National de la Recherche Scientifique (CNRS, Lasers, Plasmas and Photonics Processing Laboratory, Campus de Luminy, Marseille, France; 4The Australian National Fabrication Facility, Victoria node, Faculty of Engineering and Industrial Sciences, Swinburne University of Technology, Hawthorn, VIC, Australia Abstract: Aqueous solutions of ultra-pure gold nanoparticles have been prepared by methods of femtosecond laser ablation from a solid target and fragmentation from already formed colloids. Despite the absence of protecting ligands, the solutions could be (1 fairly stable and poly size-dispersed; or (2 very stable and monodispersed, for the two fabrication modalities, respectively. Fluorescence quenching behavior and its intricacies were revealed by fluorescence lifetime imaging microscopy in rhodamine 6G water solution. We show that surface-enhanced Raman scattering of rhodamine 6G on gold nanoparticles can be detected with high fidelity down to micromolar concentrations using the nanoparticles. Application potential of pure gold nanoparticles with polydispersed and nearly monodispersed size distributions are discussed. Keywords: nanotechnologies applications, methods of nanofabrication and processing, materials for nanomedicine

Comparative assessment of antioxidant activity of chicory products

Directory of Open Access Journals (Sweden)

Z. A. Badretdinova

2016-01-01

Full Text Available There are various methods for determining the antioxidant activity. They are differing by the source of oxidation, oxidized compounds and methods for the measurement of oxidized compounds. Methods for determination of antioxidant activity provide a wide range of results, so the evaluation of the antioxidant activity should be carried out in several ways, and the results should be interpreted with caution. In assessing antioxidant capacity is necessary to consider not only the nature and content of the reducing agent in the test facility, but also the possibility of their mutual influence. The objects of research in this research work were Instant chicory (Leroux, Fried chicory (Leroux, Instant chicory (LLC Favorit, Instant chicory (LLC SlavKofe, Instant chicory with hawthorn (Iceberg Ltd and K, Instant chicory (LLC Flagistom, Instant chicory (Ltd. Around the World, Instant chicory (LLC Beta +, Chicory flour (Leroux, Chicory flour. Antioxidant activity of the products of chicory determined by spectrophotometric (using adrenaline and 2,2 – diphenyl- 1-picrylhydrazyl, and amperometric methods. These results indicate that chicory products possess antioxidant activity but not give fully correlated with each other results. The highest antioxidant activity have fried products from chicory – Instant chicory (LLC SlavKofe and Instant chicory with hawthorn (Iceberg Ltd and K. No fried products from chicory (Chicory flour (Leroux have lower antioxidant activity then fried products from chicory. Because during frying new compounds are formed – chikoreol, which comprises acetic and valeric acid, acrolein and furfural, furfuryl alcohol, diacetyl. Best convergence results provide spectrophotometric methods using epinephrine and 2,2 – diphenyl-1-picrylhydrazyl.

Nurse Jackie and the politics of care.

Science.gov (United States)

McHugh, Kathleen

2012-01-01

This essay considers Nurse Jackie, one of several recent television shows, including HawthoRNe, and Mercy, that features a nurse as the main character. All 3 shows premiered in 2009 and challenged nursing's longstanding invisibility and misrepresentation on television. Although the plots of each show corrected problematic aspects of nursing's usual media representation, only Nurse Jackie remains on the air. In this paper, I analyze why Nurse Jackie succeeded where the other 2 shows did not, considering the representational politics of care on television and in the national context where health care remains a significant concern. Copyright © 2012 Elsevier Inc. All rights reserved.

Effects of lead-contaminated sediment and nutrition on mallard duckling brain growth and biochemistry

International Nuclear Information System (INIS)

Douglas-Stroebel, E.; Hoffman, D.J.; Brewer, G.L.; Sileo, L.

2004-01-01

Day-old mallard (Anas platyryhnchos) ducklings received either a clean sediment (24%) supplemented control diet, Coeur d'Alene River Basin, Idaho (CDARB) sediment (3449 μg/g lead) supplemented diets at 12% or 24%, or a positive control diet (24% clean sediment with equivalent lead acetate to the 24% CDARB diet) for 6 weeks. The 12% CDARB diet resulted in a geometric mean concentration of 396 ppb (WW) brain lead with decreased brain protein and ATP concentrations but increased oxidized glutathione (GSSG) relative to the control diet. The 24% CDARB diet resulted in a concentration of 485 ppb brain lead with lower brain weight and ATP concentration than controls but higher concentrations of reduced glutathione (GSH) and calcium. Lead acetate accumulated twice as well as CDARB derived lead and resulted in histopathological lesions of the brain. With a combination of a suboptimal diet and 24% CDARB, brain lead concentration was higher (594 ppb) than with 24% CDARB in the standard diet, histopathological lesions became apparent and GSH was higher than suboptimal diet controls

78 FR 4377 - Idaho Panhandle National Forests, Coeur d'Alene River Ranger District, Shoshone County, ID...

Science.gov (United States)

2013-01-22

... Ranger District, Shoshone County, ID; Beaver Creek Project AGENCY: Forest Service, USDA. ACTION: Notice of intent to prepare an environmental impact statement. SUMMARY: The Forest Service will prepare an Environmental Impact Statement (EIS) on a proposal to accomplish vegetation management in the Beaver Creek...

Milestones on a Shoestring: A Cost-Effective, Semi-automated Implementation of the New ACGME Requirements for Radiology.

Science.gov (United States)

Schmitt, J Eric; Scanlon, Mary H; Servaes, Sabah; Levin, Dayna; Cook, Tessa S

2015-10-01

The advent of the ACGME's Next Accreditation System represents a significant new challenge for residencies and fellowships, owing to its requirements for more complex and detailed information. We developed a system of online assessment tools to provide comprehensive coverage of the twelve ACGME Milestones and digitized them using freely available cloud-based productivity tools. These tools include a combination of point-of-care procedural assessments, electronic quizzes, online modules, and other data entry forms. Using free statistical analytic tools, we also developed an automated system for management, processing, and data reporting. After one year of use, our Milestones project has resulted in the submission of over 20,000 individual data points. The use of automated statistical methods to generate resident-specific profiles has allowed for dynamic reports of individual residents' progress. These profiles both summarize data and also allow program directors access to more granular information as needed. Informatics-driven strategies for data assessment and processing represent feasible solutions to Milestones assessment and analysis, reducing the potential administrative burden for program directors, residents, and staff. Copyright © 2015 AUR. Published by Elsevier Inc. All rights reserved.

Combined DECS Analysis and Next-Generation Sequencing Enable Efficient Detection of Novel Plant RNA Viruses

Directory of Open Access Journals (Sweden)

Hironobu Yanagisawa

2016-03-01

Full Text Available The presence of high molecular weight double-stranded RNA (dsRNA within plant cells is an indicator of infection with RNA viruses as these possess genomic or replicative dsRNA. DECS (dsRNA isolation, exhaustive amplification, cloning, and sequencing analysis has been shown to be capable of detecting unknown viruses. We postulated that a combination of DECS analysis and next-generation sequencing (NGS would improve detection efficiency and usability of the technique. Here, we describe a model case in which we efficiently detected the presumed genome sequence of Blueberry shoestring virus (BSSV, a member of the genus Sobemovirus, which has not so far been reported. dsRNAs were isolated from BSSV-infected blueberry plants using the dsRNA-binding protein, reverse-transcribed, amplified, and sequenced using NGS. A contig of 4,020 nucleotides (nt that shared similarities with sequences from other Sobemovirus species was obtained as a candidate of the BSSV genomic sequence. Reverse transcription (RT-PCR primer sets based on sequences from this contig enabled the detection of BSSV in all BSSV-infected plants tested but not in healthy controls. A recombinant protein encoded by the putative coat protein gene was bound by the BSSV-antibody, indicating that the candidate sequence was that of BSSV itself. Our results suggest that a combination of DECS analysis and NGS, designated here as “DECS-C,” is a powerful method for detecting novel plant viruses.

Final Long-Term Management and Storage of Elemental Mercury Environmental Impact Statement Volume 2

Energy Technology Data Exchange (ETDEWEB)

2011-01-01

Pursuant to the Mercury Export Ban Act of 2008 (P.L. 110-414), DOE was directed to designate a facility or facilities for the long-term management and storage of elemental mercury generated within the United States. Therefore, DOE has analyzed the storage of up to 10,000 metric tons (11,000 tons) of elemental mercury in a facility(ies) constructed and operated in accordance with the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act (74 FR 31723). DOE prepared this Final Mercury Storage EIS in accordance with the National Environmental Policy Act of 1969 (NEPA), as amended (42 U.S.C. 4321 et seq.), the Council on Environmental Quality (CEQ) implementing regulations (40 CFR 1500–1508), and DOE’s NEPA implementing procedures (10 CFR 1021) to evaluate reasonable alternatives for a facility(ies) for the long-term management and storage of elemental mercury. This Final Mercury Storage EIS analyzes the potential environmental, human health, and socioeconomic impacts of elemental mercury storage at seven candidate locations: Grand Junction Disposal Site near Grand Junction, Colorado; Hanford Site near Richland, Washington; Hawthorne Army Depot near Hawthorne, Nevada; Idaho National Laboratory near Idaho Falls, Idaho; Kansas City Plant in Kansas City, Missouri; Savannah River Site near Aiken, South Carolina; and Waste Control Specialists, LLC, site near Andrews, Texas. As required by CEQ NEPA regulations, the No Action Alternative was also analyzed as a basis for comparison. DOE intends to decide (1) where to locate the elemental mercury storage facility(ies) and (2) whether to use existing buildings, new buildings, or a combination of existing and new buildings. DOE’s Preferred Alternative for the long-term management and storage of mercury is the Waste Control Specialists, LLC, site near Andrews, Texas.

Final Long-Term Management and Storage of Elemental Mercury Environmental Impact Statement Summary and Guide for Stakeholders

Energy Technology Data Exchange (ETDEWEB)

2011-01-01

Pursuant to the Mercury Export Ban Act of 2008 (P.L. 110-414), DOE was directed to designate a facility or facilities for the long-term management and storage of elemental mercury generated within the United States. Therefore, DOE has analyzed the storage of up to 10,000 metric tons (11,000 tons) of elemental mercury in a facility(ies) constructed and operated in accordance with the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act (74 FR 31723). DOE prepared this Final Mercury Storage EIS in accordance with the National Environmental Policy Act of 1969 (NEPA), as amended (42 U.S.C. 4321 et seq.), the Council on Environmental Quality (CEQ) implementing regulations (40 CFR 1500–1508), and DOE’s NEPA implementing procedures (10 CFR 1021) to evaluate reasonable alternatives for a facility(ies) for the long-term management and storage of elemental mercury. This Final Mercury Storage EIS analyzes the potential environmental, human health, and socioeconomic impacts of elemental mercury storage at seven candidate locations: Grand Junction Disposal Site near Grand Junction, Colorado; Hanford Site near Richland, Washington; Hawthorne Army Depot near Hawthorne, Nevada; Idaho National Laboratory near Idaho Falls, Idaho; Kansas City Plant in Kansas City, Missouri; Savannah River Site near Aiken, South Carolina; and Waste Control Specialists, LLC, site near Andrews, Texas. As required by CEQ NEPA regulations, the No Action Alternative was also analyzed as a basis for comparison. DOE intends to decide (1) where to locate the elemental mercury storage facility(ies) and (2) whether to use existing buildings, new buildings, or a combination of existing and new buildings. DOE’s Preferred Alternative for the long-term management and storage of mercury is the Waste Control Specialists, LLC, site near Andrews, Texas.

Final Long-Term Management and Storage of Elemental Mercury Environmental Impact Statement Volume1

Energy Technology Data Exchange (ETDEWEB)

2011-01-01

Pursuant to the Mercury Export Ban Act of 2008 (P.L. 110-414), DOE was directed to designate a facility or facilities for the long-term management and storage of elemental mercury generated within the United States. Therefore, DOE has analyzed the storage of up to 10,000 metric tons (11,000 tons) of elemental mercury in a facility(ies) constructed and operated in accordance with the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act (74 FR 31723).DOE prepared this Final Mercury Storage EIS in accordance with the National Environmental Policy Act of 1969 (NEPA), as amended (42 U.S.C. 4321 et seq.), the Council on Environmental Quality (CEQ) implementing regulations (40 CFR 1500–1508), and DOE’s NEPA implementing procedures (10 CFR 1021) to evaluate reasonable alternatives for a facility(ies) for the long-term management and storage of elemental mercury. This Final Mercury Storage EIS analyzes the potential environmental, human health, and socioeconomic impacts of elemental mercury storage at seven candidate locations:Grand Junction Disposal Site near Grand Junction, Colorado; Hanford Site near Richland, Washington; Hawthorne Army Depot near Hawthorne, Nevada; Idaho National Laboratory near Idaho Falls, Idaho;Kansas City Plant in Kansas City, Missouri; Savannah River Site near Aiken, South Carolina; and Waste Control Specialists, LLC, site near Andrews, Texas. As required by CEQ NEPA regulations, the No Action Alternative was also analyzed as a basis for comparison. DOE intends to decide (1) where to locate the elemental mercury storage facility(ies) and (2) whether to use existing buildings, new buildings, or a combination of existing and new buildings. DOE’s Preferred Alternative for the long-term management and storage of mercury is the Waste Control Specialists, LLC, site near Andrews, Texas.

Insect avoidance may override human disturbances in reindeer habitat selection

Directory of Open Access Journals (Sweden)

Anna Skarin

2004-04-01

Full Text Available Habitat selection of semi-domesticated reindeer (Rangifer tarandus tarandus was investigated through faecal pellet- group counts and by direct observations of reindeer from helicopter in the Långfjället area in Idre reindeer herding district (62˚10’N and in Mittådalen reindeer herding district (62˚50’N, aerial observations only. Reindeer pellets were found to be most abundant in habitats at high altitudes, and in some vegetation types. Pellet-group densities tended to be higher near the tourist trails, which often follow higher altitudes in the terrain. The aerial surveys showed that the reindeer moved towards higher altitudes when the wind speed was low and the temperature was high both in June and July. In June they moved towards lower regions when temperature was low and the wind speed was strong. The conclusion is that the reindeer use Långfjället to escape insect harassment and warm weather, even though disturbance by tourism sometimes is high.Abstract in Swedish / Sammanfattning:Habitatval hos tamren (Rangifer tarandus tarandus undersöktes genom att göra en spillningsinventering och genom att göra flygobservationer från helikopter. Studien gjordes på Långfjället (62˚10’N i Idre nya sameby och i Mittådalens samebys sommarbetesområde (62˚50’N, endast flygobservationer. På Långfjället finns det vandringsleder som är frekventerade av vandrare från juni månad fram till september. Spillningen visade att renarna föredrog höjderna i området samt en del av vegetationstyperna. Det var också mer spillning närmare vandringslederna. Detta kan förklaras av att vandringslederna följer höjderna i terrängen. Flyginventeringarna under både juni och juli visade att renarna rörde sig mot högre terräng när det var varmt och lugnt väder. I juni rörde dom sig också i lägre terräng när det var stark vind och kallt väder. Slutsatsen är att renarna väljer att vistas i högre terräng för att undvika st

Prospects of improvement of accelerated bread technologies by usage of dogrose and hawthorn

OpenAIRE

Лебеденко, Тетяна Євгеніївна; Кожевнікова, Вікторія Олегівна; Новічкова, Тамара Петрівна

2014-01-01

In this article the analysis of main problems of baking industry connected with introduction of resource-saving technologies and reduction of quality of derivable product has been conducted; the current problems facing bread manufacturers have been determined. The objective of this research is the development of methods of complex increase of quality of products, their consumer properties, safety and nutritional value by usage of fruit phyto-additives.In this work on the basis of analysis of ...

A Lacanian Reading of the Two Novels The Scarlet Letter And Private Memoirs And Confessions of A Justified Sinner

Directory of Open Access Journals (Sweden)

Marjan Yazdanpanahi

2016-07-01

Full Text Available This paper discusses two novels The Private Memoirs and Confessions of a Justified Sinner and The Scarlet Letter written by James Hogg and Nathaniel Hawthorn from the perspective of Jacques Lacan theories: the mirror stage, the-name-of-the-father and desire. The mirror stage refers to historical value and an essential libidinal relationship with the body-image. The-name-of-the-father is defined as the prohibitive role of the father as the one who lays down the incest taboo in the Oedipus complex. Meanwhile, desire is neither the appetite for satisfaction, nor the demand for love, but the difference that results from the subtraction of the first from the second.

Special Operations Forces Aviation on a Shoestring Budget: An Effectiveness Analysis of Light and Medium Fixed Wing Aircraft

Science.gov (United States)

2012-12-01

Survivability Equipment ATK Alliant Techsystems Incorporated AVPOL Aviation, Petroleum, Oils and Lubrications BDA Battle Damage Assessment...7110.65U effective 9 February 2012, retrieved 25 March 2012, http://www.faa.gov/documentLibrary/ media /Notice/ N7110.525.pdf. 5 passenger configuration...www.faa.gov/documentLibrary/ media /Notice/ND/ N%20JO%207110.478.pdf. 11 EuroControl, “Revising wake turbulence categories to gain capacity

Solid-State Lighting on a Shoestring Budget: The Economics of Off-Grid Lighting for Small Businesses in Kenya

Energy Technology Data Exchange (ETDEWEB)

Radecsky, Kristen; Johnstone, Peter; Jacobson, Arne; Mills, Evan

2008-12-14

superior lighting services to low income people in off-grid areas of developing countries, many of whom currently rely on fuel based lighting sources such as kerosene. If this potential is to be achieved in the near term, however, manufacturers must produce off-grid lighting products that are inexpensive, perform well, and meet the needs of potential end users. At present, relatively few products meet all three of these goals. In this article, we report results from a detailed study of lighting use by micro-enterprises in two small towns in Kenya's Rift Valley Province. The work included a survey about lighting use by 50 small businesses, careful measurements of kerosene lighting use patterns and associated costs for 23 of these businesses, and a subsequent field trial in which 14 of the 23 businesses purchased and used low cost LED lamps over a number of months.

Business Anthropology

DEFF Research Database (Denmark)

Moeran, Brian

2015-01-01

Relations School at Harvard University), as well as in the United Kingdom and elsewhere, before turning to five areas of research and practice: academic ethnographies of business practices, regional studies, case studies developed by practitioners, theoretical applications, and methods. The essay then asks......; cross-cultural comparison of work cultures; attention to the materials, technologies, and goods with which business people engage and which afford their organizational forms; and explicit attention to cutting-edge fieldwork methods.......This essay outlines the overall scope and location of business anthropology within the overall field of the discipline. It outlines its foundations as an applied form of anthropology in early developments in the United States (in particular, in Western Electric’s Hawthorne Project and the Human...

Packaging a successful NASA mission to reach a large audience within a small budget. Earth's Dynamic Space: Solar-Terrestrial Physics & NASA's Polar Mission

Science.gov (United States)

Fox, N. J.; Goldberg, R.; Barnes, R. J.; Sigwarth, J. B.; Beisser, K. B.; Moore, T. E.; Hoffman, R. A.; Russell, C. T.; Scudder, J.; Spann, J. F.; Newell, P. T.; Hobson, L. J.; Gribben, S. P.; Obrien, J. E.; Menietti, J. D.; Germany, G. G.; Mobilia, J.; Schulz, M.

2004-12-01

To showcase the on-going and wide-ranging scope of the Polar science discoveries, the Polar science team has created a one-stop shop for a thorough introduction to geospace physics, in the form of a DVD with supporting website. The DVD, Earth's Dynamic Space: Solar-Terrestrial Physics & NASA's Polar Mission, can be viewed as an end-to-end product or split into individual segments and tailored to lesson plans. Capitalizing on the Polar mission and its amazing science return, the Polar team created an exciting multi-use DVD intended for audiences ranging from a traditional classroom and after school clubs, to museums and science centers. The DVD tackles subjects such as the aurora, the magnetosphere and space weather, whilst highlighting the science discoveries of the Polar mission. This platform introduces the learner to key team members as well as the science principles. Dramatic visualizations are used to illustrate the complex principles that describe Earth’s dynamic space. In order to produce such a wide-ranging product on a shoe-string budget, the team poured through existing NASA resources to package them into the Polar story, and visualizations were created using Polar data to complement the NASA stock footage. Scientists donated their time to create and review scripts in order to make this a real team effort, working closely with the award winning audio-visual group at JHU/Applied Physics Laboratory. The team was excited to be invited to join NASA’s Sun-Earth Day 2005 E/PO program and the DVD will be distributed as part of the supporting educational packages.

Chronic Homelessness, Head Start, and Changing Federal Policies: Teaching and Learning at Hawthorne House

Science.gov (United States)

Bullough, Robert V., Jr.; Hall-Kenyon, Kendra M.

2015-01-01

Federal policy changes for Head Start (HS) elevate the importance of measured academic performance over other traditional program aims, particularly those associated with the social-emotional development of children. Concerned about the possible effects of these changes on children, based on observations and interviews, detailed portraits of…

Sympathetic ophthalmia - histopathological correlation with fluorescein and indocyanine green angiography: case report Oftalmia simpática - correlação da histopatologia com a angiografia por fluoresceína e indocianina verde: relato de caso

Directory of Open Access Journals (Sweden)

Antônio Marcelo Barbante Casella

2008-12-01

Full Text Available This study correlates fluorescein angiography (FA and indocyanine green angiography (ICGA to histopathologic findings in a patient with sympathetic ophtalmia. A male with a perforated trauma in right eye presented after two months a decrease in visual acuity of the left eye. FA and ICGA were performed and the images were correlated with the histopathologic findings of the enucleated eye; FA showed background areas of homogeneous hypofluorescence in the arterial and venous phases, as well as areas of granular progressive hyperfluorescence and leakage from the optic disc. ICGA showed areas of hypofluorescence in the early and intermediate phases of the examination, which persisted until the late phase. During the early phase, there was also diffuse hypofluorescence caused by blockage that allowed observation of areas of partial choroidal circulation. The histopathology of the enucleated right eye showed diffuse choriocapillaris edema and inflammation of the choroids, focal areas of hyperplasia of the retinal pigment epithelium (RPE as well as foci of epithelioid cells located between the choroid and the RPE. Furthermore, lymphocytic infiltration of the episcleral veins and retinal detachment were present. The hyperfluorescence observed on FA was correlated to retinal detachment and optic nerve inflammation. The hypofluorescence noted on FA and ICGA corresponded to the presence of blocking inflammatory cells (Dalen-Fuchs-like nodules and to diffuse choriocapillaris edema.O objetivo deste relato de caso foi correlacionar achados da histopatologia com a angiografia por fluoresceína (AF e por indocianina verde (AIV em um paciente com oftalmia simpática. Após dois meses de trauma perfurante no olho direito, o paciente apresentou baixa acuidade visual no olho esquerdo (OE. A AF do OE mostrou áreas de hipofluorescência homogênea na fase arterial e venosa, áreas de progressiva hiperfluorescência granular e vazamento do disco. A AIV mostrou �

Innovations on a shoestring: a study of a collaborative community-based Aboriginal mental health service model in rural Canada

Directory of Open Access Journals (Sweden)

Graham Douglas

2009-12-01

Full Text Available Abstract Background Collaborative, culturally safe services that integrate clinical approaches with traditional Aboriginal healing have been hailed as promising approaches to ameliorate the high rates of mental health problems in Aboriginal communities in Canada. Overcoming significant financial and human resources barriers, a mental health team in northern Ontario is beginning to realize this ideal. We studied the strategies, strengths and challenges related to collaborative Aboriginal mental health care. Methods A participatory action research approach was employed to evaluate the Knaw Chi Ge Win services and their place in the broader mental health system. Qualitative methods were used as the primary source of data collection and included document review, ethnographic interviews with 15 providers and 23 clients; and 3 focus groups with community workers and managers. Results The Knaw Chi Ge Win model is an innovative, community-based Aboriginal mental health care model that has led to various improvements in care in a challenging rural, high needs environment. Formal opportunities to share information, shared protocols and ongoing education support this model of collaborative care. Positive outcomes associated with this model include improved quality of care, cultural safety, and integration of traditional Aboriginal healing with clinical approaches. Ongoing challenges include chronic lack of resources, health information and the still cursory understanding of Aboriginal healing and outcomes. Conclusions This model can serve to inform collaborative care in other rural and Indigenous mental health systems. Further research into traditional Aboriginal approaches to mental health is needed to continue advances in collaborative practice in a clinical setting.

Effect of Common Species of Florida Landscaping Plants on the Efficacy of Attractive Toxic Sugar Baits Against Aedes albopictus.

Science.gov (United States)

Seeger, Kelly E; Scott, Jodi M; Muller, Gunter C; Qualls, Whitney A; Xue, Rui-De

2017-06-01

Attractive toxic sugar bait (ATSB) was applied to 5 different types of commonly found plants in landscaping of northeastern Florida. The ATSB applications were assessed for possible plant effects and preference against Aedes albopictus in semifield evaluations. Positive and negative controls consisted of plants sprayed with attractive sugar bait (no toxicant) and plants with nothing applied. Bioassays were conducted on stems with leaf clippings and on full plants to assess any difference in mosquito mortality on the different plants. Plants utilized in these evaluations were Indian hawthorne, Yaupon holly, Japanese privet, Loropetalum ruby, and podocarpus. In both assays, no significant difference was observed in the effect of ATSBs on adult female mosquitoes based on the type of plant. ATSB could be applied to common landscape plants for adult Ae. albopictus control.

The origin of the galaxy and local group

CERN Document Server

2014-01-01

This volume contains the updated and expanded lecture notes of the 37th Saas-Fee Advanced Course organised by the Swiss Society for Astrophysics and Astronomy. It offers the most comprehensive and up to date review of one of the hottest research topics in astrophysics - how our Milky Way galaxy formed. Joss Bland-Hawthorn & Ken Freeman lectured on Near Field Cosmology - The Origin of the Galaxy and the Local Group. Francesca Matteucci’s chapter is on Chemical evolution of the Milky Way and its Satellites. As designed by the SSAA, books in this series – and this one too – are targeted at graduate and PhD students and young researchers in astronomy, astrophysics and cosmology. Lecturers and researchers entering the field will also benefit from the book.

BIOLOGICAL VALUE OF PUNY FRUITS RELATED TO THEIR ANTIRADICAL ACTIVITY

Directory of Open Access Journals (Sweden)

M. BALOGHOVÁ

2007-05-01

Full Text Available All analysed species of puny fruits (red currant (Ribes rubrum L variant Jonkheervan Tets, white currant (Ribes vulgare L. variant Blanka, black currant (Ribesnigrum L. variant Eva, blueberry (Vaccinium myrtilis variant Berkeley, elderberry(Sambucus nigra L. variant Sambo, hawthorn (Crataegus oxyacantha, mulberry(Morus nigra L. genotypes M152 and M047 are natural sources of anthocyanpigments and vitamin C with a high antiradical activity. Due to the fact that thehighest antiradical activity is not accompanied by the highest content of anthocyansand vitamin C in puny fruits, we suppose that the antiradical activity of plantmaterials is also connected with the presence of other compounds with antioxidantand antiradical activity. From our results follows that all studied puny fruits with ahigh antiradical activity increase the antioxidant value of human nutrition and alsoits prophylactic and medicinal effect.

The Origin of the Galaxy and Local Group

Science.gov (United States)

Bland-Hawthorn, Joss; Freeman, Ken; Matteucci, Francesca

This volume contains the updated and expanded lecture notes of the 37th Saas-Fee Advanced Course organised by the Swiss Society for Astrophysics and Astronomy. It offers the most comprehensive and up to date review of one of the hottest research topics in astrophysics - how our Milky Way galaxy formed. Joss Bland-Hawthorn & Ken Freeman lectured on Near Field Cosmology - The Origin of the Galaxy and the Local Group. Francesca Matteucci's chapter is on Chemical evolution of the Milky Way and its Satellites. As designed by the SSAA, books in this series - and this one too - are targeted at graduate and PhD students and young researchers in astronomy, astrophysics and cosmology. Lecturers and researchers entering the field will also benefit from the book. *%K Physics, Astrophysics, Near Field Cosmology, Galaxy, Local Group *%O Milky Way

The role of selected plant metabolites in host plant choice by caterpillars of Acrobasis advenella (Zincken, 1818 (Lepidoptera, Pyralidae

Directory of Open Access Journals (Sweden)

Górska-Drabik Edyta

2017-03-01

Full Text Available Acrobasis advenella is an oligophagous species feeding on plants of the Rosaceae family. The differences in concentrations of host plant quality components, above all primary metabolites and the presence or absence of secondary metabolites, directly affects herbivore growth and development. The objectives of this research were to determine the food preferences of 1st instar larvae according to the chemical composition of host plants. The highest acceptance of rowan in the free choice test by 1st instar larvae, as compared to hawthorn and black chokeberry, is positively influenced by the high content of total sugars and phenolic acids. The conclusion to be drawn from the results is that the differences in food choice by 1st instar larvae feeding on fruits could have been due to the different chemical compositions of the fruit.

Automated in vivo platform for the discovery of functional food treatments of hypercholesterolemia.

Directory of Open Access Journals (Sweden)

Robert M Littleton

Full Text Available The zebrafish is becoming an increasingly popular model system for both automated drug discovery and investigating hypercholesterolemia. Here we combine these aspects and for the first time develop an automated high-content confocal assay for treatments of hypercholesterolemia. We also create two algorithms for automated analysis of cardiodynamic data acquired by high-speed confocal microscopy. The first algorithm computes cardiac parameters solely from the frequency-domain representation of cardiodynamic data while the second uses both frequency- and time-domain data. The combined approach resulted in smaller differences relative to manual measurements. The methods are implemented to test the ability of a methanolic extract of the hawthorn plant (Crataegus laevigata to treat hypercholesterolemia and its peripheral cardiovascular effects. Results demonstrate the utility of these methods and suggest the extract has both antihypercholesterolemic and postitively inotropic properties.

Influence of local regulations on TN dual purpose BWR casks

International Nuclear Information System (INIS)

Samson, P.; Neider, T.

1999-01-01

Transnucleaire (Paris, France) and Transnuclear, Inc. (Hawthorne, New York, United Sates) have both developed Pressurized Water Reactor (PWR) spent fuel casks for storage and transport purposes. The products are supplied in Europe by Transnucleaire and in the United States by Transnuclear, Inc. Now the TN Group is working on a design for Boiling Water Reactor (BWR) spent fuel assemblies: the TN 52 L cask is designed for transport and storage is Switzerland, the TN 68 cask is designed for transport and storage in the United States. For storage purpose, national regulatory requirements have to be met: each country has specific demands and criteria. As a consequence, differences between the TN 52 L design and the TN 68 design for rather similar contents appear in several fields: the design work, the licensing process, the manufacturing and the operational life. (author)

Acquiring research-grade ERPs on a shoestring budget: A comparison of a modified Emotiv and commercial SynAmps EEG system.

Science.gov (United States)

Barham, Michael P; Clark, Gillian M; Hayden, Melissa J; Enticott, Peter G; Conduit, Russell; Lum, Jarrad A G

2017-09-01

This study compared the performance of a low-cost wireless EEG system to a research-grade EEG system on an auditory oddball task designed to elicit N200 and P300 ERP components. Participants were 15 healthy adults (6 female) aged between 19 and 40 (M = 28.56; SD = 6.38). An auditory oddball task was presented comprising 1,200 presentations of a standard tone interspersed by 300 trials comprising a deviant tone. EEG was simultaneously recorded from a modified Emotiv EPOC and a NeuroScan SynAmps RT EEG system. The modifications made to the Emotiv system included attaching research grade electrodes to the Bluetooth transmitter. Additional modifications enabled the Emotiv system to connect to a portable impedance meter. The cost of these modifications and portable impedance meter approached the purchase value of the Emotiv system. Preliminary analyses revealed significantly more trials were rejected from data acquired by the modified Emotiv compared to the SynAmps system. However, the ERP waveforms captured by the Emotiv system were found to be highly similar to the corresponding waveform from the SynAmps system. The latency and peak amplitude of N200 and P300 components were also found to be similar between systems. Overall, the results indicate that, in the context of an oddball task, the ERP acquired by a low-cost wireless EEG system can be of comparable quality to research-grade EEG acquisition equipment. © 2017 Society for Psychophysiological Research.

COLOR CHARACTERISTICS OF DRIED THREE-COMPONENT FRUIT AND BERRY PASTES

Directory of Open Access Journals (Sweden)

O. Cherevko

2018-04-01

Full Text Available Color characteristics of compositions of three-component fruit and berry pastes before and after infrared drying are determined. The compositions were prepared on the basis of apples, cranberries, and hawthorn with increased nutrition value and therapeutic and prophylactic properties, according to the suggested recipe. The ratio of the components in the first composition is 60 : 30 : 10, in the second, 65 : 25 : 10, and in the third, 55 : 40 : 5. The resulting compositions were controlled by the control (apple paste. To dry the compositions obtained, it is proposed to use a roller IR dryer based on a flexible resistive film electric heater of emitting type. The prepared paste compositions are reddish-orange according to the color characteristics determined. Color characteristics of dried three-component fruit and berry pastes are also determined. The wavelength of composition 1 is 498 nm, and those of compositions 2 and 3 are 620.5 and 589.4 nm, respectively. The first composition is bluish-purple, with tone purity 34.7 %. Composition 2 is red (34.8 %, composition 3 is bluish-red (34.6 %. The comparison of the color characteristics of compositions of three-component fruit and berry pastes before and after infrared drying as for the brightness and tone purity of the samples indicates a slight change in brightness within 2—6 %. Reduction of the color purity to almost a half is due to the drying shrinkage of the mass of raw materials and obtaining a visual color of the compositions that is attractive for a consumer. According to the results of expert evaluation of the quality indices of dried three-component fruit and berry paste compositions, a certain advantage is determined of the dried composition with the following ratio of components in the recipe: apple, cranberry, hawthorn — 60 : 30 : 10 (composition 1. The suggested compositions of dried three-component fruit and berry paste are recommended for use in food rations

Determination of diethyl phthalate and polyhexamethylene guanidine in surrogate alcohol from Russia.

Science.gov (United States)

Monakhova, Yulia B; Kuballa, Thomas; Leitz, Jenny; Lachenmeier, Dirk W

2011-01-01

Analytical methods based on spectroscopic techniques were developed and validated for the determination of diethyl phthalate (DEP) and polyhexamethylene guanidine (PHMG), which may occur in unrecorded alcohol. Analysis for PHMG was based on UV-VIS spectrophotometry after derivatization with Eosin Y and (1)H NMR spectroscopy of the DMSO extract. Analysis of DEP was performed with direct UV-VIS and (1)H NMR methods. Multivariate curve resolution and spectra computation methods were used to confirm the presence of PHMG and DEP in the investigated beverages. Of 22 analysed alcohol samples, two contained DEP or PHMG. (1)H NMR analysis also revealed the presence of signals of hawthorn extract in three medicinal alcohols used as surrogate alcohol. The simple and cheap UV-VIS methods can be used for rapid screening of surrogate alcohol samples for impurities, while (1)H NMR is recommended for specific confirmatory analysis if required.

Determination of Diethyl Phthalate and Polyhexamethylene Guanidine in Surrogate Alcohol from Russia

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Yulia B. Monakhova

2011-01-01

Full Text Available Analytical methods based on spectroscopic techniques were developed and validated for the determination of diethyl phthalate (DEP and polyhexamethylene guanidine (PHMG, which may occur in unrecorded alcohol. Analysis for PHMG was based on UV-VIS spectrophotometry after derivatization with Eosin Y and 1H NMR spectroscopy of the DMSO extract. Analysis of DEP was performed with direct UV-VIS and 1H NMR methods. Multivariate curve resolution and spectra computation methods were used to confirm the presence of PHMG and DEP in the investigated beverages. Of 22 analysed alcohol samples, two contained DEP or PHMG. 1H NMR analysis also revealed the presence of signals of hawthorn extract in three medicinal alcohols used as surrogate alcohol. The simple and cheap UV-VIS methods can be used for rapid screening of surrogate alcohol samples for impurities, while 1H NMR is recommended for specific confirmatory analysis if required.

Characterization of apple stem grooving virus and apple chlorotic leaf spot virus identified in a crab apple tree.

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Li, Yongqiang; Deng, Congliang; Bian, Yong; Zhao, Xiaoli; Zhou, Qi

2017-04-01

Apple stem grooving virus (ASGV), apple chlorotic leaf spot virus (ACLSV), and prunus necrotic ringspot virus (PNRSV) were identified in a crab apple tree by small RNA deep sequencing. The complete genome sequence of ACLSV isolate BJ (ACLSV-BJ) was 7554 nucleotides and shared 67.0%-83.0% nucleotide sequence identity with other ACLSV isolates. A phylogenetic tree based on the complete genome sequence of all available ACLSV isolates showed that ACLSV-BJ clustered with the isolates SY01 from hawthorn, MO5 from apple, and JB, KMS and YH from pear. The complete nucleotide sequence of ASGV-BJ was 6509 nucleotides (nt) long and shared 78.2%-80.7% nucleotide sequence identity with other isolates. ASGV-BJ and the isolate ASGV_kfp clustered together in the phylogenetic tree as an independent clade. Recombination analysis showed that isolate ASGV-BJ was a naturally occurring recombinant.

B. F. Skinner and T. N. Whitehead: A Brief Encounter, Research Similarities, Hawthorne Revisited, What Next?

Science.gov (United States)

Claus, Calvin K.

2007-01-01

B. F. Skinner and T. N. Whitehead recalled a personal interaction in 1934, with differing memories of the event. No evidence of other subsequent interactions or mutual citations has been found. Although they went their separate ways, three similarities in their research strategies have been found and are discussed. Elements of Whitehead's…

Performance of Two Bioswales on Urban Runoff Management

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Qingfu Xiao

2017-09-01

Full Text Available This study evaluated the effectiveness of two bioswales eight years after construction in Davis, California. The treatment bioswale measured 9 m × 1 m × 1 m (L × W × D. Engineered soil mix (75% native lava rock and 25% loam soil replaced the native loam soil. Four Red Tip Photinia (Photinia × fraseri Dress trees and two Blueberry Muffin Hawthorn (Rhaphiolepis umbellata (Thunb. Makino shrubs were planted in the bioswale. Runoff flowed into the bioswale from an adjacent 171 m2 panel of turf grass. An identically sized control bioswale consisting of non-disturbed native soil was located adjacent to the treatment bioswale. Surface runoff quantity and quality were measured during three experiments with different pollutant loads. When compared to the control, the treatment bioswale reduced surface runoff by 99.4%, and reduced nitrogen, phosphate, and total organic carbon loading by 99.1%, 99.5%, and 99.4%, respectively. After eight years, tree growth characteristics were similar across both sites.

Effect of nanofiltration on the antioxidant properties of Crataegus monogyna curative extracts

International Nuclear Information System (INIS)

Mitev, D.; Vlakhov, E.; Vlakhov, T.; Peshev, D.; Hristova-Avakumova, N.; Hadjimitova, V.

2016-01-01

Treatment of pathological conditions with medicinal and aromatic plants is an ancient approach of treatment and prevention. Basis of a properly conducted therapy is the effective component and precise dosage. To realize the therapeutic properties, in many cases separation and concentration of the active ingredients are essential steps. We chose Crataegus monogyna (hawthorn) as one of the most common species used in traditional herbalism, which is of considerable interest as a natural sedative and for treating cardiac ailments. The plant parts used medicinally are usually sprigs with both leaves and flowers, or alternatively the fruit. Both of them showed substantial content of antioxidant phytochemicals, although quantification of total phenolic/reducers content (TPC) and radical scavenging ability in parallel expressed significant prevalence of 'leaves with flowers' extract vs. 'fruits' one. Membrane concentration was shown an effective means for direct increase of bioactive components. A strong correlation between antiradical capacities of the extracts and their TPC was established.

Designing universal primers for the isolation of DNA sequences encoding Proanthocyanidins biosynthetic enzymes in Crataegus aronia

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Zuiter Afnan

2012-08-01

Full Text Available Abstract Background Hawthorn is the common name of all plant species in the genus Crataegus, which belongs to the Rosaceae family. Crataegus are considered useful medicinal plants because of their high content of proanthocyanidins (PAs and other related compounds. To improve PAs production in Crataegus tissues, the sequences of genes encoding PAs biosynthetic enzymes are required. Findings Different bioinformatics tools, including BLAST, multiple sequence alignment and alignment PCR analysis were used to design primers suitable for the amplification of DNA fragments from 10 candidate genes encoding enzymes involved in PAs biosynthesis in C. aronia. DNA sequencing results proved the utility of the designed primers. The primers were used successfully to amplify DNA fragments of different PAs biosynthesis genes in different Rosaceae plants. Conclusion To the best of our knowledge, this is the first use of the alignment PCR approach to isolate DNA sequences encoding PAs biosynthetic enzymes in Rosaceae plants.

A Starry Diamond in a Veil of Light: Artistic and Literary Suggestions of a Comet

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Gasperini, A.; Galli, D.

2016-01-01

Donati's Comet, discovered in Florence on June 2, 1858, was one of the most spectacular astronomical events of the nineteenth century. It could be seen with the naked eye during September and October 1858, when it reached its highest splendour. The sight of the comet, with its bright nucleus and its long, curved tail, inspired paintings, watercolors, engravings, and sketches by artists such as William Dyce, Samuel Palmer, and William Turner of Oxford. Donati's Comet is mentioned in the works of several contemporary writers and poets (Hawthorne, Dickens, Hardy, and Verne), and in the diaries of explorers and travelers all around the world. Long-lasting traces of the impression left by Donati's Comet are found in many forms of popular art and literature (ladies' magazines, children's books, collection cards, and advertisements) until the beginning of the twentieth century. This paper focuses on a few examples of this fascination, emphasizing the connections among the astronomical event and the artistic sensibility of the period.

A novel herbal treatment reduces depressive-like behaviors and increases brain-derived neurotrophic factor levels in the brain of type 2 diabetic rats

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Luo C

2016-11-01

Full Text Available Chun Luo,1,* Yuting Ke,1,* Yanyan Yuan,1 Ming Zhao,1 Fuyan Wang,1 Yisheng Zhang,2 Shizhong Bu1 1Runliang Diabetes Laboratory, Diabetes Research Center, Ningbo University, 2Department of Gynaecology and Obstetrics, Ningbo Medical Center, Li Huili Eastern Hospital, Ningbo, Zhejiang, People’s Republic of China *These authors contributed equally to this work Background: Radix Puerariae and hawthorn fruit have been demonstrated to treat diabetes. They offer potential benefits for preventing depression in diabetes. Objective: The aim of this study was to investigate whether the combination of Radix Puerariae and hawthorn fruit (CRPHF could prevent depression in a diabetic rat model generated by feeding the rats with a high-fat diet and a low-dose streptozotocin (STZ. Methods: The CRPHF was provided by the Shanghai Chinese Traditional Medical University. Twenty-four rats were randomly divided into four groups: normal control, normal-given-CRPHF (NC, diabetic control, and diabetic-given-CRPHF (DC groups. The type 2 diabetic model was created by feeding the rats with a high-fat diet for 4 weeks followed by injection of 25 mg/kg STZ. CRPHF was given at 2 g/kg/d to the rats of NC and DC groups by intragastric gavage daily for 4 weeks after the type 2 diabetic model was successfully created. Body weight, random blood glucose (RBG, oral glucose tolerance test, total cholesterol (TC, triglyceride (TG, high-density lipoprotein cholesterol (HDL-C, and low-density lipoprotein cholesterol (LDL-C were measured during the study. Depressive-like behavior was evaluated at the end of the treatment by using the open field test (OFT, the elevated plus-maze test (EPMT, locomotor activity test (LAT, and forced swimming test (FST. Levels of extracellular signal-regulated protein kinase (ERK and brain-derived neurotrophic factor (BDNF in the prefrontal cortex were evaluated by using Western blot. Results: 1 CRPHF reduced RBG and improved glucose tolerance in diabetic rats

High-Precision Locations and the Stress Field from Instrumental Seismicity, Moment Tensors, and Short-Period Mechanisms through the Mina Deflection, Central Walker Lane

Science.gov (United States)

Ruhl, C. J.; Smith, K. D.

2012-12-01

The Mina Deflection (MD) region of the central Walker Lane of eastern California and western Nevada, is a complex zone of northeast-trending normal, and primarily left-lateral strike-slip to oblique-slip faulting that separates the Southern Walker Lane (SWL) from a series of east-tilted normal fault blocks in the Central Walker Lane (CWL) (Faulds and Henry, 2008; Surpless, 2008). The MD accommodates the transfer of right-lateral strike-slip motion from northwest-striking faults in the SWL to a series of left-stepping northwest-striking right-lateral strike-slip faults in the CWL, east of the Wassuk Range near Hawthorne, NV. The ~50 km wide ~80 km long right-step is a distinct transition in regional physiography that has been attributed to strain accommodation through pre-Cenozoic lithospheric structures. Several slip transfer mechanisms have been proposed within the MD, from clockwise rotation of high-angle fault blocks (Wesnousky, 2005), to low-angle displacement within the Silver Peak-Lone Mountain complex (Oldow et al., 2001), and curved fault arrays associated with localized basins and tectonic depressions (Ferranti et al., 2009). The region has been a regular source of M4+ events, the most recent being an extended sequence that included twenty-seven M 3.5+ earthquakes (largest event M 4.6) south of Hawthorne in 2011. These earthquakes (Mina, NV, and the 1932 M 7.1 Cedar Mountains earthquake east of the Pilot Mountains. Another persistent feature in the seismicity is an ~40 km long arcuate distribution of activity extending from approximately Queen Valley, north of the White Mountains, to Mono Lake that appears to reflect a southwestern boundary to northeast-striking structures in the MD. Here we develop high-precision relocations of instrumental seismicity in the MD from 1984 through 2012, including relocations of the 2004 sequence, and account for the historical seismic record. MT solutions from published reports and computed from recent M 3.5+ earthquakes as

Sources, transport, and trends for selected trace metals and nutrients in the Coeur d'Alene and Spokane River Basins, Idaho, 1990-2013

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Clark, Gregory M.; Mebane, Christopher A.

2014-01-01

Data collected at 18 streamflow-gaging and water-quality sampling sites in the Coeur d’Alene and Spokane River Basins of northern Idaho were used to estimate mean streamflow‑weighted concentrations and annual loads of total and dissolved cadmium, lead, and zinc, and total phosphorus (TP) and nitrogen (TN) for water years (WYs) 2009–13. Chronic Ambient Water Quality Criteria (AWQC) and AWQC ratios also were calculated to evaluate Idaho aquatic life criteria for chronic exposure to cadmium and zinc in streams. At four sites with a longer period of record, a Seasonal Kendall trend test was used to assess historical trends in the concentrations of total cadmium, lead, and zinc, and chronic AWQC ratios for cadmium and zinc during WYs 1990–2013.

Report: Examination of Costs Claimed under EPA Grant X96906001 Awarded to Walker Lake Working Group, Hawthorne, Nevada

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Report #10-2-0054, January 6, 2010. The grantee did not meet financial management requirements specified by Title 40 Code of Federal Regulations Part 30 and Title 2 Code of Federal Regulations Part 30.

New technologies for low emissions

Energy Technology Data Exchange (ETDEWEB)

Burnett, G. [Kansas City Power & Light (USA)

2001-05-01

This paper examines new technology for coal-fired power stations, designed to achieve very low emissions with focus on the post-combustion emissions control systems installed at Howthorn. The first post-combustion system through which the flue gas passes is a selective catalytic reduction (SCR) system, consisting of two catalyst-equipped casing and various support equipment designed to provide continuous control of NOx emissions. The second system is a dry flue gas desulphurisation (dry FGD) system consisting of two spray dry absorber (SDA) vessels and supporting equipment to provide control of SO{sub 2} emissions. The third system consists of a pulse-jet bag house (PJBH) and supporting equipment to control particulate emissions. Finally, the fourth system is a material handling system (ash handling system), consisting of equipment provided to remove, recycle, and dispose of solid wastes associated with the combustion process and the three other pollution control systems. These systems bring the operation of Hawthorn 5 into compliance with federal, state, and local emission standards and enhance the positive relationship KCP & L has with its neighbours. 6 figs., 1 tab.

Discharge, water temperature, and water quality of Warm Mineral Springs, Sarasota County, Florida: A retrospective analysis

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Metz, Patricia A.

2016-09-27

Warm Mineral Springs, located in southern Sarasota County, Florida, is a warm, highly mineralized, inland spring. Since 1946, a bathing spa has been in operation at the spring, attracting vacationers and health enthusiasts. During the winter months, the warm water attracts manatees to the adjoining spring run and provides vital habitat for these mammals. Well-preserved late Pleistocene to early Holocene-age human and animal bones, artifacts, and plant remains have been found in and around the spring, and indicate the surrounding sinkhole formed more than 12,000 years ago. The spring is a multiuse resource of hydrologic importance, ecological and archeological significance, and economic value to the community.The pool of Warm Mineral Springs has a circular shape that reflects its origin as a sinkhole. The pool measures about 240 feet in diameter at the surface and has a maximum depth of about 205 feet. The sinkhole developed in the sand, clay, and dolostone of the Arcadia Formation of the Miocene-age to Oligocene-age Hawthorn Group. Underlying the Hawthorn Group are Oligocene-age to Eocene-age limestones and dolostones, including the Suwannee Limestone, Ocala Limestone, and Avon Park Formation. Mineralized groundwater, under artesian pressure in the underlying aquifers, fills the remnant sink, and the overflow discharges into Warm Mineral Springs Creek, to Salt Creek, and subsequently into the Myakka River. Aquifers described in the vicinity of Warm Mineral Springs include the surficial aquifer system, the intermediate aquifer system within the Hawthorn Group, and the Upper Floridan aquifer in the Suwannee Limestone, Ocala Limestone, and Avon Park Formation. The Hawthorn Group acts as an upper confining unit of the Upper Floridan aquifer.Groundwater flow paths are inferred from the configuration of the potentiometric surface of the Upper Floridan aquifer for September 2010. Groundwater flow models indicate the downward flow of water into the Upper Floridan aquifer

Influences upon pediatricians’ willingness to refer patients to clinical research

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Jeanne Dalen

2010-03-01

Full Text Available Jeanne Dalen1, Robert D Annett2, Janet L Brody1, Mandy L Perryman31Center for Family and Adolescent Research, Oregon Research Institute, Portland, OR, USA; 2University of New Mexico Health Sciences Center, Albuquerque, NM, USA; 3School of Education and Human Development, Lynchburg College, Lynchburg, UA, USAPurpose: The purpose of this brief report is to determine factors that influence the willingness of pediatricians to refer their patients to clinical research and to explore the relationship between pediatrician characteristics and self-reported number of patients referred to clinical research.Method: Forty-three pediatricians from an academic pediatrics department of a university children’s hospital in Albuquerque, New Mexico rated how influential 10 reasons would be in their decision to refer a patient to pediatric clinical research.Results: Differences among the influences for pediatrician referral to research were observed. The most influential consideration for referral was the scientific merit of the study, followed by patient benefit. Contextual factors and physician compensation were identified as the least important reasons pediatricians refer patients to research. Analyses also revealed significant relationships between referrals made and percentage of time spent in research activities.Conclusions: Pediatricians may be more likely to refer their patients to clinical research studies when they believe the purpose of the study is meaningful to patients as well as to future patient populations. In addition, characteristics of the individual pediatricians may play an important role in actual referral behavior.Keywords: recruitment, clinical research, adolescent research, pediatrician attitudes

Sympathetic ophthalmitis following vitreoretinal surgery: Does antecedent trauma make a difference?

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Ekta Rishi

2015-01-01

Full Text Available Background: Sympathetic ophthalmitis (SO has been reported following vitrectomy; however, there is a lack of data on the role of antecedent penetrating ocular trauma impacting the disease manifestation in eyes developing SO following vitrectomy. Aim: To report differences in the presentation and outcomes of SO in eyes with or without a history of antecedent penetrating trauma; SO being diagnosed after vitreoretinal (VR surgery. Design: Comparative case series. Methods: Seventeen consecutive patients presenting with SO following VR surgery, diagnosed between 1995 and 2011 were included. Eyes with and without prior penetrating injury were included in Group I (n = 7 and Group II (n = 10, respectively. All Group I patients had received systemic steroids prior to presentation. Demographic and clinical parameters were evaluated. Results: Differences were observed between Group I and Group II mainly with regards to time interval between VR surgery and diagnosis of SO (1.5 months vs. 8 months, P = 0.10, presence of neurosensory detachments (100% vs. 30%, P = 0.01, and the inciting eye vision at presentation (nil light perception in 28.5% vs. 80%, P = 0.049. Other differences observed though not statistically significant were optic disc and retinal vessel involvement (42% vs. 70%, P = 0.28, Dalen-Fuchs nodules (localized vs. diffuse and leaks on fundus fluorescein angiography (pin-head vs. pin-point leak. Conclusion: SO in patients with antecedent penetrating ocular trauma present early with the central serous chorioretinopathy-like picture. Prior use of systemic steroids might have a bearing on the differences in presentation and the visual acuities between the two groups.

Die literêre vertaler as kulturele bemiddelaar

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M.B. Müller

2008-07-01

Full Text Available The literary translator as a cultural mediator The translation process is an intercultural transfer that does not only take place between two languages, but between two cultures, as the source and target text are each embedded in a communicative situation in their respective cultures. The literary translator is thus faced with the problem of how to handle the cultural aspects implicit in a source text, and of choosing the most suitable technique to convey these aspects to the target text successfully while keeping in mind the characteristics of the intended readers. The translator can thus be regarded as a cultural mediator who facilitates communication and understanding between people or groups who differ with regard to language and culture. The various culture-specific words and concepts in Dalene Matthee’s “Fiela se kind” have far-reaching implications for translation. The extent to which the translator – Matthee herself – succeeded in functioning as a cultural mediator in “Fiela’s child” is investigated in this article by means of contrastive analysis. It is argued that a decisive loss of meaning and emotional value occured during the translation process to the detriment of the target text as a literary work. The contention of this article is that Matthee’s way of handling translation problems on a microstructural level brought about macrotextual semantic shifts in the target text, and that she did not succeed in fulfilling her role as a cultural mediator at all the levels of the text.

Landscapes of The Mind: The Setting as Psyche in Nathaniel Hawthorne's The Scarlet Letter And F. Scott Fitzgerald's The Great Gatsby Landscapes of The Mind: The Setting as Psyche in Nathaniel Hawthorne's The Scarlet Letter And F. Scott Fitzgerald's The Great Gatsby

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Cruce Stark

2009-09-01

Full Text Available In the closing moment of F. Scott Fitzgerald's The Great Gateby, Nick returns for one last look at what once was Gateby's house. But instead of physical buildings, he has a vision of an earlier time, a vision of the "old island" that "flowered once for Dutch sailor's eyes -- a fresh green breast of the new world." "For a transitory enchanted moment," Nick thinks, "man must have held his breath in the presence of this continent, compelled into an aesthetic contemplation he neither understood nor desired, face to face for the last time in history with something commensurate to his capacity for wonder (182." In the closing moment of F. Scott Fitzgerald's The Great Gateby, Nick returns for one last look at what once was Gateby's house. But instead of physical buildings, he has a vision of an earlier time, a vision of the "old island" that "flowered once for Dutch sailor's eyes -- a fresh green breast of the new world." "For a transitory enchanted moment," Nick thinks, "man must have held his breath in the presence of this continent, compelled into an aesthetic contemplation he neither understood nor desired, face to face for the last time in history with something commensurate to his capacity for wonder (182."

Replicating the Networking, Mentoring and Venture Creation Benefits of Entrepreneurship Centres on a Shoestring: A Student-Centered Approach to Entrepreneurship Education and Venture Creation

Science.gov (United States)

Bell, Robin; Bell, Heather

2016-01-01

As support for both university-level entrepreneurship education and the use of experiential learning methods to foster student entrepreneurs has increased, so too has the number of university-established or affiliated entrepreneurship centres. This study focuses on an activity designed to combine experiential learning methods with assets…

Using Innovative Tools to Teach Computer Application to Business Students--A Hawthorne Effect or Successful Implementation Here to Stay

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Khan, Zeenath Reza

2014-01-01

A year after the primary study that tested the impact of introducing blended learning and guided discovery to help teach computer application to business students, this paper looks into the continued success of using guided discovery and blended learning with learning management system in and out of classrooms to enhance student learning.…

Parallels in the Beliefs and Works of Margaret Fuller and Carl Jung

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Jerry Aldridge

2011-05-01

Full Text Available Margaret Fuller, the 19th-century feminist and Transcendentalist, has been compared with Louisa May Alcott, Ralph Waldo Emerson, Nathaniel Hawthorne, and Henry David Thoreau. The life and theories of Carl Jung, the 20th-century psychiatrist, have been compared with the works of Sigmund Freud, Alfred Adler, Jean Piaget, and Sabina Spielrein among others. However, no comparisons have been published concerning the beliefs and works of Fuller and Jung. The purpose of this research was to compare and contrast the beliefs and written works of Margaret Fuller and Carl Jung. Similarities and differences were reported among their ideologies. Similarities in their childhood and adult dreams, literary references, spiritual beliefs, and explorations of gender were described. Differences were reported, which included the focus of their writings and their ideas about who is to blame when things go wrong, and how to deal with the individual daemon in each person was also explored. Special consideration was given to how closely their writings intersect. Specifically, the authors questioned whether Jung was inspired by the ideas and writings of Fuller. To answer this question, five possibilities were identified.

Aortic Relaxant Activity of Crataegus gracilior Phipps and Identification of Some of Its Chemical Constituents

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Abigail Hernández-Pérez

2014-12-01

Full Text Available This study focused on the assessment of the vasorelaxant activity of the organic and aqueous extracts obtained from leaves and fruits of a Mexican hawthorn (Crataegus gracilior on isolated rat aorta, and on the purification and identification of some of their secondary metabolites by the use of chromatographic and spectroscopic techniques. The results obtained showed that the methanol extract has a significantly more potent and effective vasorelaxant effect than the other tested extracts, with an EC50 = 8.69 ± 4.34 µg/mL and an Emax = 94.6% ± 11.30%, values that are close to that of acetylcholine, the positive control. From the same extract, two major triterpenes were isolated and identified as ursolic and corosolic acids by comparison of their experimental NMR spectroscopic data with those reported in the literature. Chlorogenic acid, rutin, quercetin, kaempferol and (+-catechin were also identified using HPLC coupled with PDAD. All these compounds have already been proven to possess on their own antihypertensive effect and other benefits on cardiovascular diseases and they can support, at least in part, the traditional use of this plant species.

Tooth brushing, oil pulling and tissue regeneration: A review of holistic approaches to oral health.

Science.gov (United States)

Singh, Abhinav; Purohit, Bharathi

2011-04-01

Even though dentistry was not a specialized branch of Ayurveda, it is included in its Shalakya Tantra (system of surgery). Problems such as deformities of the oral cavity, plaques and infections were managed in ancient India. Traditional medicine can treat various infectious and chronic conditions. Research has shown that all kinds of chewing sticks described in ancient Ayurveda texts have medicinal and anti-cariogenic properties. Its oil pulling (Kaval, Gandush) practice is claimed to cure about 30 systemic diseases. Amla (Emblic myrobalan), is a general rebuilder of oral health. Bilberry fruit (Vaccinium myrtillus) and hawthorn berry (Crateagus oxycanthus) stabilize collagen, strengthening the gum tissue. Liquorice root (Glycyrrhiza glabral) promotes anti-cavity action, reduces plaque, and has an antibacterial effect. Use of safe, quality products and practices should be ensured based on available evidence if traditional medicine is to be acknowledged as part of primary health care. Scientific validations of the Ayurveda dental health practices could justify their incorporation into modern dental care. Publicity of these techniques using appropriate media would benefit the general population by giving more confidence in the ancient practices, thus preventing tooth decay and loss.

Seed predators exert selection on the subindividual variation of seed size.

Science.gov (United States)

Sobral, M; Guitián, J; Guitián, P; Larrinaga, A R

2014-07-01

Subindividual variation among repeated organs in plants constitutes an overlooked level of variation in phenotypic selection studies, despite being a major component of phenotypic variation. Animals that interact with plants could be selective agents on subindividual variation. This study examines selective pressures exerted during post-dispersal seed predation and germination on the subindividual variation of seed size in hawthorn (Crataegus monogyna). With a seed offering experiment and a germination test, we estimated phenotypic selection differentials for average and subindividual variation of seed size due to seed predation and germination. Seed size affects germination, growth rate and the probability of an individual seed of escaping predation. Longer seeds showed higher germination rates, but this did not result in significant selection on phenotypes of the maternal trees. On the other hand, seed predators avoided wider seeds, and by doing so exerted phenotypic selection on adult average and subindividual variation of seed size. The detected selection on subindividual variation suggests that the levels of phenotypic variation within individual plants may be, at least partly, the adaptive consequence of animal-mediated selection. © 2013 German Botanical Society and The Royal Botanical Society of the Netherlands.

Games, civil war and mutiny: metaphors of conflict for the nurse-doctor relationship in medical television programmes.

Science.gov (United States)

Weaver, Roslyn

2013-12-01

Metaphors of medicine are common, such as war, which is evident in much of our language about health-care where patients and healthcare professionals fight disease, or the game, which is one way to frame the nurse-doctor professional relationship. This study analyses six pilot episodes of American (Grey's Anatomy, Hawthorne, Mercy, Nurse Jackie) and Australian (All Saints, RAN) medical television programmes premiering between 1998 and 2009 to assess one way that our contemporary culture understands and constructs professional relationships between nurses and doctors. Analysis shows that these popular television programmes frequently depict conflict, with games, civil war and mutiny between nurses and doctors over patient safety rather than professionals working collaboratively in teams to deliver health-care. Although the benefit of this televised conflict is the implication that nurses are knowledgeable, skilled professionals, the negative connotations include a dysfunctional and dangerous healthcare system, and also ongoing power struggles. Given that popular culture can sometimes influence the public's understanding of real-life nursing practice, it is important to explore what these metaphors of conflict are communicating about the nurse-doctor relationship. © 2013 John Wiley & Sons Ltd.

Tooth brushing, oil pulling and tissue regeneration: A review of holistic approaches to oral health

Directory of Open Access Journals (Sweden)

Abhinav Singh

2011-01-01

Full Text Available Even though dentistry was not a specialized branch of Ayurveda, it is included in its Shalakya Tantra (system of surgery. Problems such as deformities of the oral cavity, plaques and infections were managed in ancient India. Traditional medicine can treat various infectious and chronic conditions. Research has shown that all kinds of chewing sticks described in ancient Ayurveda texts have medicinal and anti-cariogenic properties. Its oil pulling (Kaval, Gandush practice is claimed to cure about 30 systemic diseases. Amla (Emblic myrobalan, is a general rebuilder of oral health. Bilberry fruit (Vaccinium myrtillus and hawthorn berry (Crateagus oxycanthus stabilize collagen, strengthening the gum tissue. Liquorice root (Glycyrrhiza glabral promotes anti-cavity action, reduces plaque, and has an antibacterial effect. Use of safe, quality products and practices should be ensured based on available evidence if traditional medicine is to be acknowledged as part of primary health care. Scientific validations of the Ayurveda dental health practices could justify their incorporation into modern dental care. Publicity of these techniques using appropriate media would benefit the general population by giving more confidence in the ancient practices, thus preventing tooth decay and loss.

Assessment of the Dutch National Air Quality Plan 2004; Beoordeling van het Nationaal Luchtkwaliteitsplan 2004

Energy Technology Data Exchange (ETDEWEB)

Beck, J.P.; Buringh, E.; Wieringa, K.

2005-02-01

The Dutch government expects that targets for the reduction of emission of particulates and nitrogen dioxide can not be reached in time. Therefore, the Netherlands is obliged to draft a plan of actions in order to realize those targets within the period that has been agreed upon in the context of the European Union air quality policy. The present plan of action has been assessed by the Netherlands Environmental Assessment Agency (MNP) with regard to the feasibility of the boundary values and the preconditions for action plans as formulated by the European Committee. Also, the plan has been assessed for the prevention or limitation of health effects and the Dutch position with regard to particulates. [Dutch] Het luchtbeleid heeft als doelstelling dat op lange termijn de gezondheidsrisico's en de effecten op ecosystemen en biodiversiteit moeten dalen tot een verwaarloosbaar niveau. Daartoe zijn in Europees verband normen voor de luchtkwaliteit vastgesteld. Nederland verwacht dat met het vastgestelde beleid niet tijdig aan de grenswaarden voor fijn stof en stikstofdioxide zal worden voldaan. Hierdoor is Nederland verplicht om een actieplan op te stellen. De uitvoering ervan zal er toe moeten leiden dat Nederland alsnog de doelen binnen de gestelde termijn haalt. Het Milieu- en Natuurplanbureau (MNP) van het RIVM heeft het actieplan getoetst aan de haalbaarheid van grenswaarden en aan de voorwaarden die door de Europese Commissie voor actieplannen zijn opgesteld. Daarnaast is het plan beoordeeld in het perspectief van de doelstelling van de richtlijn: het voorkomen of verminderen van gezondheidseffecten. Tenslotte geeft de evaluatie aanknopingspunten voor het herijken van de Nederlandse positie in de fijnstofproblematiek.

Hydrogeologic Investigation, Water Chemistry Analysis, and Model Delineation of contributing Areas for City of Tallahassee Public-Supply Wells, Tallahassee, Florida

Science.gov (United States)

Davis, J. Hal; Katz, Brian G.

2007-01-01

Ground water from the Upper Floridan aquifer is the sole source of water supply for Tallahassee, Florida, and the surrounding area. The City of Tallahassee (the City) currently operates 28 water-supply wells; 26 wells are distributed throughout the City and 2 are located in Woodville, Florida. Most of these wells yield an ample supply of potable water; however, water from several wells has low levels of tetrachloroethylene (PCE). The City removes the PCE from the water by passing it through granular-activated carbon units before distribution. To ensure that water-supply wells presently free of contamination remain clean, it is necessary to understand the ground-water flow system in sufficient detail to protect the contributing areas. Ground-water samples collected from four public-supply wells were analyzed for tritium (3H), chlorofluorocarbons (CFCs), and sulfur hexafluoride (SF6). Using data for the CFC compounds, apparent ground-water ages ranged from 7 to 31 years. For SF6, the apparent ages tended to be about 5 to 10 years younger than those from CFCs. Apparent ages based on the tritium/tritiogenic helium-3 (3H/3Hetrit) method ranged from 26 to 33 years. The three dating methods indicate that the apparent age of ground water generally decreases from northern to southern Leon County. This southward trend of decreasing ages is consistent with increasing amounts of recharge that occur as ground water moves from north to south. The ground-water age data derived by geochemical and tracer analyses were used in combination with the flow model and particle tracking to determine an effective porosity for the Hawthorn clays and Upper Floridan aquifer. The effective porosities for the Upper Floridan aquifer that resulted in best model matches were averaged to produce an effective porosity of 7 percent, and the effective porosities for the Hawthorn clays that resulted in a match were averaged to produce an effective porosity of 22 percent. Probabilistic contributing areas

A randomized comparison between records made with an anesthesia information management system and by hand, and evaluation of the Hawthorne effect.

Science.gov (United States)

Edwards, Kylie-Ellen; Hagen, Sander M; Hannam, Jacqueline; Kruger, Cornelis; Yu, Richard; Merry, Alan F

2013-10-01

Anesthesia information management system (AIMS) technology is designed to facilitate high-quality anesthetic recordkeeping. We examined the hypothesis that no difference exists between AIMS and handwritten anesthetic records in regard to the completeness of important information contained as text data. We also investigated the effect of observational research on the completeness of anesthesiologists' recordkeeping. As part of a larger randomized controlled trial, participants were randomized to produce 400 anesthetic records, either handwritten (n = 200) or using an AIMS (n = 200). Records were assessed against a 32-item checklist modified from a clinical guideline. Intravenous agent and bolus recordings were quantified, and data were compared between handwritten and AIMS records. Records produced with intensive research observation during the initial phase of the study (n = 200) were compared with records produced with reduced intensity observation during the final phase of the study (n = 200). The AIMS records were more complete than the handwritten records (mean difference 7.1%; 95% confidence interval [CI] 5.6 to 8.6%; P < 0.0001), with higher completion rates for six individual items on the checklist (P < 0.0001). Drug annotation data were equal between arms. The records completed early in the study, during a period of more intense observation, were more thorough than subsequent records (87.3% vs 81.6%, respectively; mean difference 5.7%; 95% CI 4.2 to 7.3%; P < 0.0001). The AIMS records were more complete than the handwritten records for 32 predefined items. The potential of observational research to influence professional behaviour in an anesthetic context was confirmed. This trial was registered at the Australian New Zealand Clinical Trials Registry No 12608000068369.

Functional foods and dietary supplements for the management of dyslipidaemia.

Science.gov (United States)

Hunter, Paola M; Hegele, Robert A

2017-05-01

Dyslipidaemia is characterized by increased blood levels of total or LDL cholesterol and triglycerides, or decreased HDL cholesterol levels, and is a risk factor for cardiovascular disease. Dyslipidaemia has a high worldwide prevalence, and many patients are turning to alternatives to pharmacotherapy to manage their lipid levels. Lifestyle modification should be emphasized in all patients to reduce cardiovascular risk and can be initiated before pharmacotherapy in primary prevention of cardiovascular disease. Many functional foods and natural health products have been investigated for potential lipid-lowering properties. Those with good evidence for a biochemical effect on plasma lipid levels include soy protein, green tea, plant sterols, probiotic yogurt, marine-derived omega-3 fatty acids and red yeast rice. Other products such as seaweed, berberine, hawthorn and garlic might confer some limited benefit in certain patient groups. Although none of these products can reduce lipid levels to the same extent as statins, most are safe to use in addition to other lifestyle modifications and pharmacotherapy. Natural health products marketed at individuals with dyslipidaemia, such as policosanol, guggulsterone and resveratrol, have minimal definitive evidence of a biochemical benefit. Additional research is required in this field, which should include large, high-quality randomized controlled trials with long follow-up periods to investigate associations with cardiovascular end points.

Alliances in Human Biology: The Harvard Committee on Industrial Physiology, 1929-1939.

Science.gov (United States)

Oakes, Jason

2015-08-01

In 1929 the newly-reorganized Rockefeller Foundation funded the work of a cross-disciplinary group at Harvard University called the Committee on Industrial Physiology (CIP). The committee's research and pedagogical work was oriented towards different things for different members of the alliance. The CIP program included a research component in the Harvard Fatigue Laboratory and Elton May's interpretation of the Hawthorne Studies; a pedagogical aspect as part of Wallace Donham's curriculum for Harvard Business School; and Lawrence Henderson's work with the Harvard Pareto Circle, his course Sociology 23, and the Harvard Society of Fellows. The key actors within the CIP alliance shared a concern with training men for elite careers in government service, business leadership, and academic prominence. But the first communications between the CIP and the Rockefeller Foundation did not emphasize training in human biology. Instead, the CIP presented itself as a coordinating body that would be able to organize all the varied work going on at Harvard that did not fit easily into one department, and it was on this basis that the CIP became legible to the President of Harvard, A. Lawrence Lowell, and to Rockefeller's Division of Social Sciences. The members of the CIP alliance used the term human biology for this project of research, training and institutional coordination.

Phenolic Composition and Antioxidant and Antimicrobial Activities of Extracts Obtained from Crataegus azarolus L. var. aronia (Willd. Batt. Ovaries Calli

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Radhia Bahri-Sahloul

2014-01-01

Full Text Available Objective. Plant cell culture is an innovative technology to produce a variety of substances. Numerous plants synthesize among their secondary metabolites phenolic compounds which possess antioxidant and antimicrobial effects. Hawthorn (Crataegus is one of these plants which has long been used in folk medicine and is widely utilized in pharmaceutical preparations mainly in neuro- and cardiosedative actions. Methods and Results. The production of polyphenol by fifty-two-week-old Crataegus azarolus var. aronia calli was studied in relation to growth variation and antioxidant and antimicrobial capacity within a subcultured period. The DPPH and ABTS+ assays were used to characterize the antioxidant actions of the callus cultures. Antimicrobial activity was tested by using disc diffusion and dilution assays for the determination of the minimal inhibitory concentration (MIC and the minimal bactericidal concentration (MBC values of each active extract. High TEACDPPH, TEACABTS, and antimicrobial activity was observed when maximal growth was reached. An optimum of total phenol, proanthocyanidins, flavonoid, (−-epicatechin, procyanidin B2, chlorogenic acid, and hyperoside was produced during this period. Conclusion. Antioxidant and antimicrobial activities were strongly correlated with total phenols and total flavonoids. Crataegus azarolus var. aronia cells culture represents an important alternative source of natural antioxidants and antimicrobials.

Suitability of thermoluminescence, chemiluminescence, ESR and viscosity measurements as detection method for the irradiation of medicinal herbs

International Nuclear Information System (INIS)

Schuettler, C.; Gebhardt, G.; Stock, A.; Helle, N.; Boegl, K.W.

1993-01-01

Chemiluminescence, electron spin resonance, thermoluminescence and viscosity measurements have been investigated for their suitability as detection method for the irradiation of the medicinal herbs anise seeds (anisi fructus), valerian roots (valerianae radix), redberry leaves (uvae ursi folium), birch leaves (betulae folium), greek hay seeds (foenugraeci semen), cayenne pepper (capsici fructus acer), black-aldertee bark (frangulae cortex), fennel fruits (feoniculi fructus), rose hip shells (cynosbati fructus), coltsfoot (farfarae folium), acorus roots (calami rhizoma), chamomile flowers (matricariae flos), caraway (carvi fructus), lavender flowers (lavandulae flos), linseed (lini semen), lime tree flowers (tiliae flos), St. Mary's thistle fruit (cardui mariae herba), lemon balm (melissae folium), java tea (orthosiphonis folium), peppermint (menthae piperitae folium), sage leaves (salviae folium), scouring rush (equiseti herba), senna leaves (sennae folium), plantain herbs (plantaginis lanceolata herba), thyme herbs (thymi herba), juniper berries (juniperi fructus), hawthorne herbs (crataegi folium), wheat starch (amylum tritici) and wormwood (absinthii herba). Depending on the herbs, the methods used were more or less suitable. Chemiluminescence measurements showed the smallest differences between untreated and irradiated samples whereas thermoluminescence measurements on isolated minerals from the vegetable drugs gave better results. In some herbs radiation-specific radicals could be identified by ESR spectroscopy. Viscosity measurement is suitable for some herbs as fast and inexpensive method for screening. (orig.) [de

Effect of Some Antioxidants on the Physical Fitness of Albino Rats

International Nuclear Information System (INIS)

Michael, M.I.

2011-01-01

In recent years, more attention has been paid for searching of natural antioxidants and their evaluation in either medicinal practice or as food raw materials. The aim of the present research is to assess the effect of several well-known products used as antioxidants, on body weight, haemopoesis, endocrine system and lipid profile in normal albino rats. Thirty male adult albino rats were equally arranged into 5 groups, the first group was served as control and the others received special treatments where taurine (2% in drinking water), tryptophan (100 mg/kg b.w. orally), hawthorn extract (50 mg/100 g b.w. orally) and coenzyme Q10 (50 mg/kg b.w. orally) were given for two months. Body weight was regularly recorded twice a week and at the end of the experiment, the rats were decapitated. Red blood cell count (RBCs), hemoglobin (Hb) content, reticulocytic count, white blood cell count (WBCs) and glutathione (GSH) concentration were estimated in blood, while, triiodothyronine (T 3 ), thyroxin (T 4 ), Testosterone, and corticosterone hormones besides lipid profile were estimated in the serum. The results denoted that although there is a slight improvement in the parameters tested, it does not deserve the coast of the regular use of these antioxidants and further investigations still needed

University of Idaho Water of the West Initiative: Development of a sustainable, interdisciplinary water resources program

Science.gov (United States)

Boll, J.; Cosens, B.; Fiedler, F.; Link, T.; Wilson, P.; Harris, C.; Tuller, M.; Johnson, G.; Kennedy, B.

2006-12-01

Recently, an interdisciplinary group of faculty from the University of Idaho was awarded a major internal grant for their project "Water of the West (WoW)" to launch an interdisciplinary Water Resources Graduate Education Program. This Water Resources program will facilitate research and education to influence both the scientific understanding of the resource and how it is managed, and advance the decision-making processes that are the means to address competing societal values. By educating students to integrate environmental sciences, socio-economic, and political issues, the WoW project advances the University's land grant mission to promote economic and social development in the state of Idaho. This will be accomplished through novel experiential interdisciplinary education activities; creation of interdisciplinary research efforts among water resources faculty; and focusing on urgent regional problems with an approach that will involve and provide information to local communities. The Water Resources Program will integrate physical and biological sciences, social science, law, policy and engineering to address problems associated with stewardship of our scarce water resources. As part of the WoW project, faculty will: (1) develop an integrative problem-solving framework; (2) develop activities to broaden WR education; (3) collaborate with the College of Law to offer a concurrent J.D. degree, (4) develop a virtual system of watersheds for teaching and research, and (5) attract graduate students for team-based education. The new program involves 50 faculty from six colleges and thirteen departments across the university. This university-wide initiative is strengthened by collaboration with the Idaho Water Resources Research Institute, and participation from off-campus Centers in Idaho Falls, Boise, Twin Falls, and Coeur d'Alene. We hope this presentation will attract university faculty, water resources professionals, and others for stimulating discussions on

Columbia River system operation review. Final environmental impact statement

International Nuclear Information System (INIS)

1995-11-01

The Columbia River and its tributaries are the primary water system in the Pacific Northwest, draining some 219,000 square miles in seven states and another 39,500 square miles in British Columbia. Beginning in the 1930's, the Columbia River has been significantly modified by construction of 30 major dams on the river and its tributaries, along with dozens of non-Federal projects. Construction and subsequent operation of these water development projects have contributed to eight primary uses of the river system, including navigation, flood control, irrigation, electric power generation, fish migration, fish and wildlife habitat, recreation, and water supply and quality considerations. Increasing stress on the water development of the Columbia River and its tributaries has led primary Federal agencies to undertake intensive analysis and evaluation of the operation of these projects. These agencies are the U.S. Army Corps of Engineers and the Bureau of Reclamation, who operate the large Federal dams on the river, and the Bonneville Power Administration who sells the power generated at the dams. This review, termed the System Operation Review (SOR), has as its ultimate goal to define a strategy for future operation of the major Columbia River projects which effectively considers the needs of all river uses. This volume, Appendix D: Cultural resources appendix, Technical imput includes the following: Development of geomorphology based framework for cultural resources management, Dworshak Reservoir, Idaho; Impact profiles for SOR reservoirs; comments from the following Native American tribes: Burns Paiute Tribe; Coville Confederated Tribes; Confederated Tribes of the Warm Springs Indian Reservation; Confederated Tribes and bands of the Yakama Indian Nation (comments); Nez Perce Tribe; Coeur D'Alene Tribe; Spokane Tribe of Indians; The confederated Tribes of the Umatilla Indian Reservation

Mineral Deposit Data for Epigenetic Base- and Precious-metal and Uranium-thorium Deposits in South-central and Southwestern Montana and Southern and Central Idaho

Science.gov (United States)

Klein, T.L.

2004-01-01

Metal deposits spatially associated with the Cretaceous Boulder and Idaho batholiths of southwestern Montana and southern and central Idaho have been exploited since the early 1860s. Au was first discovered in placer deposits; exploitation of vein deposits in bedrock soon followed. In 1865, high-grade Ag vein deposits were discovered and remained economically important until the 1890s. Early high-grade deposits of Au, Ag and Pb were found in the weathered portions of the veins systems. As mining progressed to deeper levels, Ag and Pb grades diminished. Exploration for and development of these vein deposits in this area have continued until the present. A majority of these base- and precious-metal vein deposits are classified as polymetallic veins (PMV) and polymetallic carbonate-replacement (PMR) deposits in this compilation. Porphyry Cu and Mo, epithermal (Au, Ag, Hg and Sb), base- and precious-metal and W skarn, W vein, and U and Th vein deposits are also common in this area. The world-class Butte Cu porphyry and the Butte high-sulfidation Cu vein deposits are in this study area. PMV and PMR deposits are the most numerous in the region and constitute about 85% of the deposit records compiled. Several types of syngenetic/diagenetic sulfide mineral deposits in rocks of the Belt Supergroup or their equivalents are common in the region and they have been the source of a substantial metal production over the last century. These syngenetic deposits and their metamorphosed/structurally remobilized equivalents were not included in this database; therefore, deposits in the Idaho portion of the Coeur d'Alene district and the Idaho Cobalt belt, for example, have not been included because many of them are believed to be of this type.

Columbia River System Operation Review : Final Environmental Impact Statement, Appendix D: Exhibits.

Energy Technology Data Exchange (ETDEWEB)

Columbia River System Operation Review (U.S.)

1995-11-01

The Columbia River and its tributaries are the primary water system in the Pacific Northwest, draining some 219,000 square miles in seven states and another 39,500 square miles in British Columbia. Beginning in the 1930`s, the Columbia River has been significantly modified by construction of 30 major dams on the river and its tributaries, along with dozens of non-Federal projects. Construction and subsequent operation of these water development projects have contributed to eight primary uses of the river system, including navigation, flood control, irrigation, electric power generation, fish migration, fish and wildlife habitat, recreation, and water supply and quality considerations. Increasing stress on the water development of the Columbia River and its tributaries has led primary Federal agencies to undertake intensive analysis and evaluation of the operation of these projects. These agencies are the U.S. Army Corps of Engineers and the Bureau of Reclamation, who operate the large Federal dams on the river, and the Bonneville Power Administration who sells the power generated at the dams. This review, termed the System Operation Review (SOR), has as its ultimate goal to define a strategy for future operation of the major Columbia River projects which effectively considers the needs of all river uses. This volume, Appendix D: Cultural resources appendix, Technical imput includes the following: Development of geomorphology based framework for cultural resources management, Dworshak Reservoir, Idaho; Impact profiles for SOR reservoirs; comments from the following Native American tribes: Burns Paiute Tribe; Coville Confederated Tribes; Confederated Tribes of the Warm Springs Indian Reservation; Confederated Tribes and bands of the Yakama Indian Nation (comments); Nez Perce Tribe; Coeur D`Alene Tribe; Spokane Tribe of Indians; The confederated Tribes of the Umatilla Indian Reservation.

Field site investigation: Effect of mine seismicity on groundwater hydrology

International Nuclear Information System (INIS)

Ofoegbu, G.I.; Hsiung, S.; Chowdhury, A.H.

1995-04-01

The results of a field investigation on the groundwater-hydrologic effect of mining-induced earthquakes are presented in this report. The investigation was conducted at the Lucky Friday Mine, a silver-lead-zinc mine in the Coeur d'Alene Mining District of Idaho. The groundwater pressure in sections of three fracture zones beneath the water table was monitored over a 24-mo period. The fracture zones were accessed through a 360-m-long inclined borehole, drilled from the 5,700 level station of the mine. The magnitude, source location, and associated ground motions of mining-induced seismic events were also monitored during the same period, using an existing seismic instrumentation network for the mine, augmented with additional instruments installed specifically for the project by the center for Nuclear Waste Regulatory Analyses (CNWRA). More than 50 seismic events of Richter magnitude 1.0 or larger occurred during the monitoring period. Several of these events caused the groundwater pressure to increase, whereas a few caused it to decrease. Generally, the groundwater pressure increased as the magnitude of seismic event increased; for an event of a given magnitude, the groundwater pressure increased by a smaller amount as the distance of the observation point from the source of the event increased. The data was examined using regression analysis. Based on these results, it is suggested that the effect of earthquakes on groundwater flow may be better understood through mechanistic modeling. The mechanical processes and material behavior that would need to be incorporated in such a model are examined. They include a description of the effect of stress change on the permeability and water storage capacity of a fracture rock mass; transient fluid flow; and the generation and transmission of seismic waves through the rock mass

Men in nursing on television: exposing and reinforcing stereotypes.

Science.gov (United States)

Weaver, Roslyn; Ferguson, Caleb; Wilbourn, Mark; Salamonson, Yenna

2014-04-01

To describe the results of a study of images of men in nursing on television. Previous research has highlighted stereotypical images around nursing, such as the battle-axe, naughty nurse and handmaiden. More recent research focuses on images of nurses who are men, because of the growing numbers of men in the nursing workforce. Given that negative images can harm recruitment and retention in the profession, it is important to interrogate how men in nursing are portrayed in popular culture. Representations on television are particularly critical to explore because of the medium's wide audience. Qualitative study. Five American medical television programmes appearing between 2007 and 2010 were analysed for their construction of men in nursing: Grey's Anatomy, Hawthorne, Mercy, Nurse Jackie and Private Practice. Men in nursing on television were portrayed in ways that engaged with explicit and implicit stereotypes. The men were often subject to questions about their choice of career, masculinity and sexuality and their role usually reduced to that of prop, minority spokesperson or source of comedy. Thus, rather contradictorily, although the programmes often sought to expose common stereotypes about men in nursing, they nonetheless often reinforced stereotypes in more implicit ways. This research has implications for better understanding not only the status of nursing in our society but also for nursing practice and education and attracting more men to the profession. © 2013 John Wiley & Sons Ltd.

A century of work teams in the Journal of Applied Psychology.

Science.gov (United States)

Mathieu, John E; Hollenbeck, John R; van Knippenberg, Daan; Ilgen, Daniel R

2017-03-01

Work groups are a vital link between individuals and organizations. Systematic psychological research on the nature and effects of work groups dates back at least to the Hawthorne studies of the 1920s and 1930s. Yet little to none of this work appeared in the Journal of Applied Psychology until the 1950s when groups were treated primarily as foils against which to compare the performance of individuals. From the 1990s to the present, the volume of research and the nature of topics addressing work group/teams expanded significantly. The authors review the evolution of team research over the past century with a particular focus on that which has appeared in this journal. They chronicle the shift from a focus on individuals within teams, or on individual versus team comparisons, to a focus on the team itself and larger systems of teams. They describe the major outcomes studied within this literature, and how they relate to the nature of team tasks and structures. Further, the authors consider the roles of team members' characteristics and composition, and team dynamics in terms of processes and emergent states. They close with a call for future research that models dynamic team relationships in context and as they operate in complex systems. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Lessons for integrated household energy conservation policies from an intervention study in Singapore

International Nuclear Information System (INIS)

Kua, H.W.; Wong, S.E.

2012-01-01

In preparation for a community energy conservation program in the southwest district of Singapore, a pilot intervention study was conducted between August and November 2008 to study the effectiveness of tailored information and feedback in promoting household conservation. A sample of 125 households was involved in the study, of which 63 were the control group. Both self-reported behavioral changes and actual energy reductions were measured and any Hawthorne effect was identified. It was found that self-reported behavioral changes were strongly correlated to the level of trust in the energy conservation information given, the need for ease in practicing the recommended conservation measures and feeling of satisfaction in executing the measures; these results differ from several past studies on energy interventions. 60.7% of those who reported behavioral changes actually reduced energy consumption. Reasons were found and discussed. Lessons from this intervention study can be applied to design integrated policies aimed at promoting energy conservation in households. - Highlights: ► Energy intervention was implemented on 125 households. ► Outreach instruments included stickers, pamphlets and counseling. ► Self-reported behavioral and actual reductions were recorded. ► Self-reported behavioral change was only correlated to trust of information given. ► It was also correlated to ease of actions and feeling of satisfaction from actions.

Overview of medicinal plants used for cardiovascular system disorders and diseases in ethnobotany of different areas in Iran

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Baharvand-Ahmadi Babak

2016-01-01

Full Text Available Background and Aims: Today, cardiovascular diseases are the prominent cause of death in industrialized countries which include a variety of diseases such as hypertension, hyperlipidemia, thromboembolism, coronary heart disease, heart failure, etc. Recent research findings haveshown that not only the extent of cultivation and production of medicinal plants have not beenreduced, but also day-to-day production and consumption have increased. In traditional botanicalknowledge, herbal medicines are used for the treatment of cardiovascular disorders. In this study,we sought to gather and report medicinal plants used to treat these diseases in different regionsof Iran.Methods: The articles published about ethnobotanical study of cardiovascular diseases in variousregions of Iran, such as Arasbaran, Sistan, Kashan, Kerman, Isfahan Mobarakeh, Lorestan andIlam were prepared and summarized.Results: The results of ethnobotanical studies of various regions of Iran, such as Arasbaran, Sistan,Kashan, Kerman, Isfahan Mobarakeh, Lorestan and Ilam were gathered. The results showed thatsumac plants, barberry, yarrow, wild cucumber, horsetail, Eastern grape, hawthorn, wild rose,spinach, jujube, buckwheat, chamomile, chicory, thistle, Mary peas, nightshade, verbena, sorrel ,cherry, citrullus colocynthis, Peganum harmala, sesame and so many other plants are used for thetreatment of cardiovascular diseases and disorders.Conclusion: Herbal medicines are used effectively for some cardiovascular diseases. Rigoroustraining of patients to take precautions and drug interactions into account and to avoid thearbitrary use of medicinal plants is very important.

Development of Advanced High Lift Leading Edge Technology for Laminar Flow Wings

Science.gov (United States)

Bright, Michelle M.; Korntheuer, Andrea; Komadina, Steve; Lin, John C.

2013-01-01

This paper describes the Advanced High Lift Leading Edge (AHLLE) task performed by Northrop Grumman Systems Corporation, Aerospace Systems (NGAS) for the NASA Subsonic Fixed Wing project in an effort to develop enabling high-lift technology for laminar flow wings. Based on a known laminar cruise airfoil that incorporated an NGAS-developed integrated slot design, this effort involved using Computational Fluid Dynamics (CFD) analysis and quality function deployment (QFD) analysis on several leading edge concepts, and subsequently down-selected to two blown leading-edge concepts for testing. A 7-foot-span AHLLE airfoil model was designed and fabricated at NGAS and then tested at the NGAS 7 x 10 Low Speed Wind Tunnel in Hawthorne, CA. The model configurations tested included: baseline, deflected trailing edge, blown deflected trailing edge, blown leading edge, morphed leading edge, and blown/morphed leading edge. A successful demonstration of high lift leading edge technology was achieved, and the target goals for improved lift were exceeded by 30% with a maximum section lift coefficient (Cl) of 5.2. Maximum incremental section lift coefficients ( Cl) of 3.5 and 3.1 were achieved for a blown drooped (morphed) leading edge concept and a non-drooped leading edge blowing concept, respectively. The most effective AHLLE design yielded an estimated 94% lift improvement over the conventional high lift Krueger flap configurations while providing laminar flow capability on the cruise configuration.

Development and Application of UPLC-QTof/MS Method for the Differentiation between Tea Varieties

International Nuclear Information System (INIS)

Jandrić, Zora

2016-01-01

Tea (Camellia sinensis L.) is one of the most popularly consumed beverages worldwide. It has been used as a natural medicine for thousands of years, containing many compounds beneficial to health. The two most popular varieties are green (favoured in Asia) and black tea (favoured in the western countries). The different growing season, geographical regions, processing and fermentation methods create many varieties of tea, some of which have premium value compared to the others. The expansion of the consumer market, which has increased demand for “manufactured” food as well as transported “pure” food such as tea, has encouraged adulteration simply because of the prospects for increased profit. The adulteration of tea has become a common problem. Mixing exhausted tealeaves with leaves of some other plants (e.g. elder, hawthorn, sloe), addition of the dust of the tea leaves and sand, chemical enhancement of green tea (with Prussian blue and sulphate of lime or gypsum) and simply redried and resold tea-leaves, are some of the main examples of tea adulteration. To help address these issues, the Food and Environmental Protection Laboratory (FEPL) applied an untargeted metabolomics approach previously developed for some other commodities (e.g. honey, fruit juices) to investigate the possibility of distinguishing teas from different origins, and detecting varieties that had been adulterated.

Le faune et la sirène : la situation de Cuvier dans l’économie de The Marble Faun, de Nathaniel Hawthorne

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Antoine Traisnel

2012-06-01

Full Text Available Nathaniel Hawthorne’s The Marble Faun ends with one character’s polite refusal to satisfy the narrator’s curiosity concerning young Donatello’s possible animality. When asked if Donatello’s ears are as pointy as those of the book’s titular figure, the Faun of Praxiteles, Kenyon smiles inscrutably and responds: “On that point, at all events, there shall be no word of explanation.” On that “point” – that of Donatello’s ears—the author remains obstinately tight-lipped, having “hoped to mystify this anomalous creature between the Real and the Fantastic […] without impelling him to ask how Cuvier would have classified poor Donatello.” The disclosure of a small anatomical detail threatens to shatter the whole edifice of Hawthorne’s fiction. The point in question here, however, is not just the extremity that makes measurement possible but also the ungraspable limit (the punctum that undoes the logic of Cuvierian classification. Analyzing the metrics of The Marble Faun, my paper will query how the romance envisions the vanishing point of the human/animal relation.The Marble Faun s’achève sur le refus poli d’un personnage qui renâcle à satisfaire la curiosité du narrateur. Quand celui-ci lui demande si les oreilles du jeune Donatello sont aussi pointues que celles du Faune de Praxitèle, Kenyon sourit mystérieusement et répond : « On that point, at all events, there shall be no word of explanation. » Sur ce point, ou plutôt sur la pointe des oreilles de Donatello, l’« auteur » reste muet dans l’espoir, écrit-il, de situer cette créature aberrante « entre le réel et le fantastique » sans avoir à spécifier la place qu’elle occupe au sein de la taxonomie établie par Cuvier. La divulgation d’un petit détail anatomique menace de faire imploser l’édifice de la fiction hawthornienne. Le point en question, cependant, n’est pas simplement l’extrémité à partir de laquelle l’animal s’avère mesurable mais également la limite insaisissable (le punctum qui met en péril la logique de la classification cuviérienne. En se penchant sur la métrique approximative de The Marble Faun, cet article se propose d’étudier la manière dont la romance imagine le point de fuite de la relation entre l’humain et l’animal.

SULFUR POLYMER ENCAPSULATION

International Nuclear Information System (INIS)

KALB, P.

2001-01-01

Sulfur polymer cement (SPC) is a thermoplastic polymer consisting of 95 wt% elemental sulfur and 5 wt% organic modifiers to enhance long-term durability. SPC was originally developed by the U.S. Bureau of Mines as an alternative to hydraulic cement for construction applications. Previous attempts to use elemental sulfur as a construction material in the chemical industry failed due to premature degradation. These failures were caused by the internal stresses that result from changes in crystalline structure upon cooling of the material. By reacting elemental sulfur with organic polymers, the Bureau of Mines developed a product that successfully suppresses the solid phase transition and significantly improves the stability of the product. SPC, originally named modified sulfur cement, is produced from readily available, inexpensive waste sulfur derived from desulfurization of both flue gases and petroleum. The commercial production of SPC is licensed in the United States by Martin Resources (Odessa, Texas) and is marketed under the trade name Chement 2000. It is sold in granular form and is relatively inexpensive ((approx)$0.10 to 0.12/lb). Application of SPC for the treatment of radioactive, hazardous, and mixed wastes was initially developed and patented by Brookhaven National Laboratory (BNL) in the mid-1980s (Kalb and Colombo, 1985; Colombo et al., 1997). The process was subsequently investigated by the Commission of the European Communities (Van Dalen and Rijpkema, 1989), Idaho National Engineering Laboratory (Darnell, 1991), and Oak Ridge National Laboratory (Mattus and Mattus, 1994). SPC has been used primarily in microencapsulation applications but can also be used for macroencapsulation of waste. SPC microencapsulation has been demonstrated to be an effective treatment for a wide variety of wastes, including incinerator hearth and fly ash; aqueous concentrates such as sulfates, borates, and chlorides; blowdown solutions; soils; and sludges. It is not

How to eliminate the formation of chlorogenic acids artefacts during plants analysis? Sea sand disruption method (SSDM) in the HPLC analysis of chlorogenic acids and their native derivatives in plants.

Science.gov (United States)

Wianowska, Dorota; Typek, Rafał; Dawidowicz, Andrzej L

2015-09-01

The analytical procedures for determining plant constituents involve the application of sample preparation methods to fully isolate and/or pre-concentrate the analyzed substances. High-temperature liquid extraction is still applied most frequently for this purpose. The present paper shows that high-temperature extraction cannot be applied for the analysis of chlorogenic acids (CQAs) and their derivatives in plants as it causes the CQAs transformation leading to erroneous quantitative estimations of these compounds. Experiments performed on different plants (black elder, hawthorn, nettle, yerba maté, St John's wort and green coffee) demonstrate that the most appropriate method for the estimation of CQAs/CQAs derivatives is sea sand disruption method (SSDM) because it does not induce any transformation and/or degradation processes in the analyzed substances. Owing to the SSDM method application we found that the investigated plants, besides four main CQAs, contain sixteen CQAs derivatives, among them three quinic acids. The application of SSDM in plant analysis not only allows to establish a true concentration of individual CQAs in the examined plants but also to determine which chlorogenic acids derivatives are native plant components and what is their concentration level. What is even more important, the application of SSDM in plant analysis allows to eliminate errors that may arise or might have arisen in the study of chlorogenic acids and their derivatives in plant metabolism. Copyright © 2015 Elsevier Ltd. All rights reserved.

Electronic monitoring in combination with direct observation as a means to significantly improve hand hygiene compliance.

Science.gov (United States)

Boyce, John M

2017-05-01

Monitoring hand hygiene compliance among health care personnel (HCP) is an essential element of hand hygiene promotion programs. Observation by trained auditors is considered the gold standard method for establishing hand hygiene compliance rates. Advantages of observational surveys include the unique ability to establish compliance with all of the World Health Organization "My 5 Moments for Hand Hygiene" initiative Moments and to provide just-in-time coaching. Disadvantages include the resources required for observational surveys, insufficient sample sizes, and nonstandardized methods of conducting observations. Electronic and camera-based systems can monitor hand hygiene performance on all work shifts without a Hawthorne effect and provide significantly more data regarding hand hygiene performance. Disadvantages include the cost of installation, variable accuracy in estimating compliance rates, issues related to acceptance by HCP, insufficient data regarding their cost-effectiveness and influence on health care-related infection rates, and the ability of most systems to monitor only surrogates for Moments 1, 4, and 5. Increasing evidence suggests that monitoring only Moments 1, 4, and 5 provides reasonable estimates of compliance with all 5 Moments. With continued improvement of electronic monitoring systems, combining electronic monitoring with observational methods may provide the best information as part of a multimodal strategy to improve and sustain hand hygiene compliance rates among HCP. Copyright © 2017 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

The study of carbohydrate composition of chicory products

Directory of Open Access Journals (Sweden)

Z. A. Khairullina

2016-01-01

Full Text Available The main products produced from chicory in the food industry are soluble roasted chicory, roasted crushed chicory, chicory flour, inulin, oligofructose and others. Fried products are used as a substitute for coffee, because it is caffeine-free and has coffee taste and aroma. Chicory flour is used in the production of bakery products. Inulin and oligofructose are widely used in the manufacture of bakery and dairy products. The aim of this study was to investigate the carbohydrate composition of the products from chicory. The objects of research in this research work were Fried chicory (Leroux, Instant chicory (Leroux, Instant chicory (LLC Flagistom, Instant chicory with hawthorn (Iceberg Ltd and K, Instant chicory (LLC SlavKofe, Instant chicory (Ltd. Around the World, Instant chicory (LLC Favorit, Instant chicory (LLC Beta +, Dried Chirory and Dried crushed chicory № 1,2,3 (LLC Sovremennik, Chicory flour (Leroux, Inulin and Oligofructose (Spinnrad GmbH. Determination of fructans and their average degree of polymerization, the content of glucose, fructose, sucrose, which are contained in foods from chicory was carried out using biochemical method with kit Sucrose / D-Glucose / D-Fructose (R-Biopharm. Studies are suggested that fried chicory products do not contain fructans. Dried products of chicory are contained inulin, the contents of which are about 60–70%, and contained other biologically active substances. Content of fructans in commercial products, such as inulin and oligofructose is about 93% and 79%.

Diversity, evolution, and functionality of clustered regularly interspaced short palindromic repeat (CRISPR) regions in the fire blight pathogen Erwinia amylovora.

Science.gov (United States)

Rezzonico, Fabio; Smits, Theo H M; Duffy, Brion

2011-06-01

The clustered regularly interspaced short palindromic repeat (CRISPR)/Cas system confers acquired heritable immunity against mobile nucleic acid elements in prokaryotes, limiting phage infection and horizontal gene transfer of plasmids. In CRISPR arrays, characteristic repeats are interspersed with similarly sized nonrepetitive spacers derived from transmissible genetic elements and acquired when the cell is challenged with foreign DNA. New spacers are added sequentially and the number and type of CRISPR units can differ among strains, providing a record of phage/plasmid exposure within a species and giving a valuable typing tool. The aim of this work was to investigate CRISPR diversity in the highly homogeneous species Erwinia amylovora, the causal agent of fire blight. A total of 18 CRISPR genotypes were defined within a collection of 37 cosmopolitan strains. Strains from Spiraeoideae plants clustered in three major groups: groups II and III were composed exclusively of bacteria originating from the United States, whereas group I generally contained strains of more recent dissemination obtained in Europe, New Zealand, and the Middle East. Strains from Rosoideae and Indian hawthorn (Rhaphiolepis indica) clustered separately and displayed a higher intrinsic diversity than that of isolates from Spiraeoideae plants. Reciprocal exclusion was generally observed between plasmid content and cognate spacer sequences, supporting the role of the CRISPR/Cas system in protecting against foreign DNA elements. However, in several group III strains, retention of plasmid pEU30 is inconsistent with a functional CRISPR/Cas system.

76 FR 77528 - Proposed CERCLA Administrative Cost Recovery Settlement; North Hollywood Operable Unit of the San...

Science.gov (United States)

2011-12-13

...In accordance with Section 122(i) of the Comprehensive Environmental Response, Compensation, and Liability Act, as amended (``CERCLA''), 42 U.S.C. 9622(i), notice is hereby given of a proposed administrative settlement for recovery of response costs concerning the North Hollywood Operable Unit of the San Fernando Valley Area 1 Superfund Site, located in the vicinity of Los Angeles, California, with the following settling parties: Pick-Your-Part Auto Wrecking; Hayward Associates, LLC; and PNM Properties, LLC. The settlement requires the settling parties to pay a total of $102,161 to the North Hollywood Operable Unit Special Account within the Hazardous Substance Superfund. The settlement also includes a covenant not to sue the settling parties pursuant to Section 107(a) of CERCLA, 42 U.S.C. 9607(a). For thirty (30) days following the date of publication of this notice, the Agency will receive written comments relating to the settlement. The Agency will consider all comments received and may modify or withdraw its consent to the settlement if comments received disclose facts or considerations which indicate that the settlement is inappropriate, improper, or inadequate. The Agency's response to any comments received will be available for public inspection at the City of Los Angeles Central Library, Science and Technology Department, 630 West 5th Street, Los Angeles, CA 90071 and at the EPA Region 9 Superfund Records Center, Mail Stop SFD-7C, 95 Hawthorne Street, Room 403, San Francisco, CA 94105.

76 FR 79678 - Proposed CERCLA Administrative Cost Recovery Settlement; North Hollywood Operable Unit of the San...

Science.gov (United States)

2011-12-22

...In accordance with Section 122(i) of the Comprehensive Environmental Response, Compensation, and Liability Act, as amended (``CERCLA''), 42 U.S.C. 9622(i), notice is hereby given of a proposed administrative settlement for recovery of response costs concerning the North Hollywood Operable Unit of the San Fernando Valley Area 1 Superfund Site, located in the vicinity of Los Angeles, California, with the following settling parties: Pick-Your-Part Auto Wrecking; Hayward Associates, LLC; and PNM Properties, LLC. The settlement requires the settling parties to pay a total of $102,161 to the North Hollywood Operable Unit Special Account within the Hazardous Substance Superfund. The settlement also includes a covenant not to sue the settling parties pursuant to Section 107(a) of CERCLA, 42 U.S.C. 9607(a). For thirty (30) days following the date of publication of this notice, the Agency will receive written comments relating to the settlement. The Agency will consider all comments received and may modify or withdraw its consent to the settlement if comments received disclose facts or considerations which indicate that the settlement is inappropriate, improper, or inadequate. The Agency's response to any comments received will be available for public inspection at the City of Los Angeles Central Library, Science and Technology Department, 630 West 5th Street, Los Angeles, CA 90071 and at the EPA Region 9 Superfund Records Center, Mail Stop SFD-7C, 95 Hawthorne Street, Room 403, San Francisco, CA 94105.

77 FR 123 - Proposed CERCLA Administrative Cost Recovery Settlement; North Hollywood Operable Unit of the San...

Science.gov (United States)

2012-01-03

...In accordance with Section 122(i) of the Comprehensive Environmental Response, Compensation, and Liability Act, as amended (``CERCLA''), 42 U.S.C. 9622(i), notice is hereby given of a proposed administrative settlement for recovery of response costs concerning the North Hollywood Operable Unit of the San Fernando Valley Area 1 Superfund Site, located in the vicinity of Los Angeles, California, with the following settling party: Waste Management Recycling & Disposal Services of California, Inc., dba Bradley Landfill & Recycling Center. The settlement requires the settling party to pay a total of $185,734 to the North Hollywood Operable Unit Special Account within the Hazardous Substance Superfund. The settlement also includes a covenant not to sue the settling party pursuant to Section 107(a) of CERCLA, 42 U.S.C. 9607(a). For thirty (30) days following the date of publication of this notice, the Agency will receive written comments relating to the settlement. The Agency will consider all comments received and may modify or withdraw its consent to the settlement if comments received disclose facts or considerations which indicate that the settlement is inappropriate, improper, or inadequate. The Agency's response to any comments received will be available for public inspection at the City of Los Angeles Central Library, Science and Technology Department, 630 West 5th Street, Los Angeles CA 90071 and at the EPA Region 9 Superfund Records Center, Mail Stop SFD-7C, 95 Hawthorne Street, Room 403, San Francisco, CA 94105.

Taming the Wild World of Management, Performance and Communication - 13459

International Nuclear Information System (INIS)

Ford, Laurie

2013-01-01

Management has evolved a long way from its original meaning of 'governing a horse'. The industrial revolution fostered 'scientific management'; 1930's Hawthorne studies discovered that people's social interactions could alter productivity; and the dawn of the computer age in the post-war 1950's brought general systems theory into management thinking. Today, mobile wireless connectivity aims to transform ever-changing networks of players, mandates, and markets into something that can be 'managed'. So why is there no clear and simple recipe for how to practice management? We talk about financial management, safety management, and operations management, but surely the 'management' part of those endeavors will share the same set of practices. Instead, we are still arguing for 'management' to include everything from developing people to negotiating contracts. A manager's job may include many things, but one of them, the job of management, needs to be nailed down. Three standard practices for managing in a network are developed: (a) support the dialogues that connect people vital to accomplishing a goal or objective; (b) develop and sustain the scoreboards that serve as a road-map to reach the goal; and (c) control the feedback to 'govern the horse'. These three practices are useful for more than reaching goals, as they also support coordinating across boundaries and running productive meetings. The dialogues for productive relationships, scoreboards for goals and deliverables, and feedback for performance together constitute a recipe for managing in a networked world. (authors)

A Radio Study of the Ultra-luminous FIR Galaxy NGC 6240

Science.gov (United States)

Colbert, E.; Wilson, A. S.; Bland-Hawthorn, J.

1993-05-01

A number of galaxies observed in the IRAS mission are noted to emit ~ 99% of their bolometric flux in the FIR, with FIR luminosities in excess of 10(11) Lsun. The interacting galaxy NGC 6240 has often been referred to as the ``proto-typical'' ultra-luminous (L_FIR >~ 10(12) Lsun) FIR galaxy. The origin of the FIR excess remains a disputed subject in the literature. New observations of NGC 6240 were taken with the VLA at 20cm in the B-configuration, and at 3.6cm in the A-configuration. No significant radio emission was detected from or near the possible ultra-massive ``dark core'' hypothesized by Bland-Hawthorn et. al. (1991); however, approximately 30% of Seyfert galaxies have 20 cm radio luminosities weaker than the upper limit derived from the radio maps. The non-thermal radio emission from luminous FIR galaxies is tightly correlated with the FIR emission. Previous radio observations of NGC 6240 revealed two compact, steep-spectrum nuclear sources, nearly coincident with the two nuclear sources seen in optical images. The 2 images from the new VLA observations and 5 images from previous VLA observations are used to identify the morphological and spectral features of the strong, compact components in the nuclear regions (~ 3 kpc) from the nucleus. Feasible explanations for the radio emission are discussed. The models that have been proposed in the literature for the FIR excess of NGC 6240 are evaluated for consistency with the observed radio emission.

Concentrations and loads of cadmium, lead, and zinc measured near the peak of the 1999 snowmelt-runoff hydrographs for 42 water-quality stations, Coeur d'Alene River basin, Idaho

Science.gov (United States)

Woods, Paul F.

2000-01-01

The Remedial Investigation/Feasibility Study conducted by the U.S. Environmental Protection Agency within the Spokane River Basin of northern Idaho and eastern Washington included extensive data-collection activities to determine the nature and extent of trace-element contamination within the basin. The U.S. Geological Survey designed and implemented synoptic sampling of the 1999 snowmelt-runoff event at 42 water- quality stations during the 1999 water year. The distribution of the 42 stations was as follows: North Fork Coeur d’Alene River and tributaries, 4 stations; South Fork Coeur d’Alene River, 13 stations; Canyon, Ninemile, and Pine Creeks, 4 stations each; other tributaries to South Fork Coeur d’Alene River, 10 stations; and main stem Coeur d’Alene River, 3 stations. The objective was to synoptically collect discharge and water-quality data in order to significantly improve the estimation of trace-element loads from multiple contributing source areas during the snowmelt-runoff event. Discharge and water-quality data were collected near the peak discharge during late May 1999. Each station was sampled for whole-water recoverable and dissolved concentrations and loads of cadmium, lead, and zinc.

Dissolved and labile concentrations of Cd, Cu, Pb, and Zn in the South Fork Coeur d'Alene River, Idaho: Comparisons among chemical equilibrium models and implications for biotic ligand models

Science.gov (United States)

Balistrieri, L.S.; Blank, R.G.

2008-01-01

In order to evaluate thermodynamic speciation calculations inherent in biotic ligand models, the speciation of dissolved Cd, Cu, Pb, and Zn in aquatic systems influenced by historical mining activities is examined using equilibrium computer models and the diffusive gradients in thin films (DGT) technique. Several metal/organic-matter complexation models, including WHAM VI, NICA-Donnan, and Stockholm Humic model (SHM), are used in combination with inorganic speciation models to calculate the thermodynamic speciation of dissolved metals and concentrations of metal associated with biotic ligands (e.g., fish gills). Maximum dynamic metal concentrations, determined from total dissolved metal concentrations and thermodynamic speciation calculations, are compared with labile metal concentrations measured by DGT to assess which metal/organic-matter complexation model best describes metal speciation and, thereby, biotic ligand speciation, in the studied systems. Results indicate that the choice of model that defines metal/organic-matter interactions does not affect calculated concentrations of Cd and Zn associated with biotic ligands for geochemical conditions in the study area, whereas concentrations of Cu and Pb associated with biotic ligands depend on whether the speciation calculations use WHAM VI, NICA-Donnan, or SHM. Agreement between labile metal concentrations and dynamic metal concentrations occurs when WHAM VI is used to calculate Cu speciation and SHM is used to calculate Pb speciation. Additional work in systems that contain wide ranges in concentrations of multiple metals should incorporate analytical speciation methods, such as DGT, to constrain the speciation component of biotic ligand models. ?? 2008 Elsevier Ltd.

EPR spectra induced by gamma-irradiation of some dry medical herbs

Science.gov (United States)

Yordanov, N. D.; Lagunov, O.; Dimov, K.

2009-04-01

The radiation-induced EPR spectra in some medical herbs are reported. The samples studied are: (i) leaves of nettle, common balm, peppermint and thyme; (ii) stalks of common balm, thyme, milfoil, yarrow and marigold; (iii) blossoms of yarrow and marigold; (iv) blossoms and leaves of hawthorn and tutsan; and (v) roots of common valerian, nettle, elecampane (black and white), restharrows and carlina. Before irradiation all samples exhibit one weak anisotropic singlet EPR line with effective g-value of 2.0050±0.0002. The radiation-induced spectra fall into three groups. EPR spectra of irradiated blossoms of yarrow and marigold, stalks of common balm, thyme, tutsan and yarrow as well as roots of common valerian, nettle and elecampane (black and white) show "cellulose-like" EPR spectrum typical for irradiated plants. It is characterized by one intense central line with g=2.0050±0.0005 and two weak satellite lines situated ca. 30 G left and right to it. EPR spectra of gamma-irradiated restharrows and carlina are complex. They may be represented by one triplet corresponding to the "cellulose-like" EPR spectrum, one relatively intense singlet, situated in the center of the spectrum, and five weak additional satellite lines left and right to the center. The last spectrum was assigned as "carbohydrate-like" type. Only one intense EPR singlet with g=2.0048±0.0005 was recorded after irradiation of leaves of nettle and common balm. The lifetime of the radiation-induced EPR spectra was followed for a period of 3 months.

EPR spectra induced by gamma-irradiation of some dry medical herbs

International Nuclear Information System (INIS)

Yordanov, N.D.; Lagunov, O.; Dimov, K.

2009-01-01

The radiation-induced EPR spectra in some medical herbs are reported. The samples studied are: (i) leaves of nettle, common balm, peppermint and thyme; (ii) stalks of common balm, thyme, milfoil, yarrow and marigold; (iii) blossoms of yarrow and marigold; (iv) blossoms and leaves of hawthorn and tutsan; and (v) roots of common valerian, nettle, elecampane (black and white), restharrows and carlina. Before irradiation all samples exhibit one weak anisotropic singlet EPR line with effective g-value of 2.0050±0.0002. The radiation-induced spectra fall into three groups. EPR spectra of irradiated blossoms of yarrow and marigold, stalks of common balm, thyme, tutsan and yarrow as well as roots of common valerian, nettle and elecampane (black and white) show 'cellulose-like' EPR spectrum typical for irradiated plants. It is characterized by one intense central line with g=2.0050±0.0005 and two weak satellite lines situated ca. 30 G left and right to it. EPR spectra of gamma-irradiated restharrows and carlina are complex. They may be represented by one triplet corresponding to the 'cellulose-like' EPR spectrum, one relatively intense singlet, situated in the center of the spectrum, and five weak additional satellite lines left and right to the center. The last spectrum was assigned as 'carbohydrate-like' type. Only one intense EPR singlet with g=2.0048±0.0005 was recorded after irradiation of leaves of nettle and common balm. The lifetime of the radiation-induced EPR spectra was followed for a period of 3 months

Taming the Wild World of Management, Performance and Communication - 13459

Energy Technology Data Exchange (ETDEWEB)

Ford, Laurie [Critical Path Consultants, 3101 Splitrock Road, Columbus Ohio 43221 (United States)

2013-07-01

Management has evolved a long way from its original meaning of 'governing a horse'. The industrial revolution fostered 'scientific management'; 1930's Hawthorne studies discovered that people's social interactions could alter productivity; and the dawn of the computer age in the post-war 1950's brought general systems theory into management thinking. Today, mobile wireless connectivity aims to transform ever-changing networks of players, mandates, and markets into something that can be 'managed'. So why is there no clear and simple recipe for how to practice management? We talk about financial management, safety management, and operations management, but surely the 'management' part of those endeavors will share the same set of practices. Instead, we are still arguing for 'management' to include everything from developing people to negotiating contracts. A manager's job may include many things, but one of them, the job of management, needs to be nailed down. Three standard practices for managing in a network are developed: (a) support the dialogues that connect people vital to accomplishing a goal or objective; (b) develop and sustain the scoreboards that serve as a road-map to reach the goal; and (c) control the feedback to 'govern the horse'. These three practices are useful for more than reaching goals, as they also support coordinating across boundaries and running productive meetings. The dialogues for productive relationships, scoreboards for goals and deliverables, and feedback for performance together constitute a recipe for managing in a networked world. (authors)

Interventions to improve teamwork and communications among healthcare staff.

Science.gov (United States)

McCulloch, P; Rathbone, J; Catchpole, K

2011-04-01

Concern over the frequency of unintended harm to patients has focused attention on the importance of teamwork and communication in avoiding errors. This has led to experiments with teamwork training programmes for clinical staff, mostly based on aviation models. These are widely assumed to be effective in improving patient safety, but the extent to which this assumption is justified by evidence remains unclear. A systematic literature review on the effects of teamwork training for clinical staff was performed. Information was sought on outcomes including staff attitudes, teamwork skills, technical performance, efficiency and clinical outcomes. Of 1036 relevant abstracts identified, 14 articles were analysed in detail: four randomized trials and ten non-randomized studies. Overall study quality was poor, with particular problems over blinding, subjective measures and Hawthorne effects. Few studies reported on every outcome category. Most reported improved staff attitudes, and six of eight reported significantly better teamwork after training. Five of eight studies reported improved technical performance, improved efficiency or reduced errors. Three studies reported evidence of clinical benefit, but this was modest or of borderline significance in each case. Studies with a stronger intervention were more likely to report benefits than those providing less training. None of the randomized trials found evidence of technical or clinical benefit. The evidence for technical or clinical benefit from teamwork training in medicine is weak. There is some evidence of benefit from studies with more intensive training programmes, but better quality research and cost-benefit analysis are needed. Copyright © 2011 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.

[Efficacy of the strategy to improve the quality indicators of Diabetes Mellitus 2 Care Process in Advanced Diabetes Centre Macarena].

Science.gov (United States)

Vélez, Juan Manuel; García, Rosa; Pina, Enrique; Morales, Cristóbal; Escalera, Carmen; Ortega, Antonio; Poyatos, Blas; Carrasco, Dolores; Prieto, Jesús; Ángeles Eslava, M; Antonio Corrales, J; Barón, María O; Llano, Mercedes; Ruiz, Francisco; Sánchez, Romualdo; Victorino Pino, Manuel; Luisa Redondo, M; Castellanos, Antonio; Mayoral, Eduardo

2018-02-21

The assessment of the Diabetes Mellitus 2 Care Process (PAI-DM2) through the assessment tool for the chronic illness' care models (IEMAC-Diabetes) allows the design of health interventions for the improvement of medical care. Analysing the quality of healthcare provided to DM2 patients. Quasiexperimental study before and after intervention with a not randomised control group. Health care district of primary care Sevilla. 12 groups of ascribed patients, 5 Primary Care Healthcenter, chosen in a discretionary way. Physicians and nurses from the 12 intervention groups took part in a training program, including an external rotation in the Diabetes Daycare Hospital. Number of included patients, glycated hemoglobin, feet exploration (FE), and ocular fundus (OF). 1,475 DM-2 patients were analysed. The proportion of included patients per group was 8.5%, 45.5% were women. At the beginning of the study, the rate of patients with HbA1c<7% were 38.9% in 2013 against 47.7% in 2014 and 40.2% in 2016; 33% of the patients had an OF in 2013 against 41.77% in 2014; 51.6% of patients had an EF against 54.7% in 2014. After the intervention, statistically significant differences were reached in HbA1c (p=0.01) and retinography requested (p=0.01). IEMAC-Diabetes allows spotting improvement areas in the PAI-DM2. The absence of statistically significant differences may be the result of contamination in the sample and/or Hawthorne effect. Copyright © 2017 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.

Fermented Chinese formula Shuan-Tong-Ling attenuates ischemic stroke by inhibiting inflammation and apoptosis

Directory of Open Access Journals (Sweden)

Zhi-gang Mei

2017-01-01

Full Text Available The fermented Chinese formula Shuan-Tong-Ling is composed of radix puerariae (Gegen, salvia miltiorrhiza (Danshen, radix curcuma (Jianghuang, hawthorn (Shanzha, salvia chinensis (Shijianchuan, sinapis alba (Baijiezi, astragalus (Huangqi, panax japonicas (Zhujieshen, atractylodes macrocephala koidz (Baizhu, radix paeoniae alba (Baishao, bupleurum (Chaihu, chrysanthemum (Juhua, rhizoma cyperi (Xiangfu and gastrodin (Tianma, whose aqueous extract was fermented with lactobacillus, bacillus aceticus and saccharomycetes. Shuan-Tong-Ling is a formula used to treat brain diseases including ischemic stroke, migraine, and vascular dementia. Shuan-Tong-Ling attenuated H2O2-induced oxidative stress in rat microvascular endothelial cells. However, the potential mechanism involved in these effects is poorly understood. Rats were intragastrically treated with 5.7 or 17.2 mL/kg Shuan-Tong-Ling for 7 days before middle cerebral artery occlusion was induced. The results indicated Shuan-Tong-Ling had a cerebral protective effect by reducing infarct volume and increasing neurological scores. Shuan-Tong-Ling also decreased tumor necrosis factor-α and interleukin-1β levels in the hippocampus on the ischemic side. In addition, Shuan-Tong-Ling upregulated the expression of SIRT1 and Bcl-2 and downregulated the expression of acetylated-protein 53 and Bax. Injection of 5 mg/kg silent information regulator 1 (SIRT1 inhibitor EX527 into the subarachnoid space once every 2 days, four times, reversed the above changes. These results demonstrate that Shuan-Tong-Ling might benefit cerebral ischemia/reperfusion injury by reducing inflammation and apoptosis through activation of the SIRT1 signaling pathway.

EPR spectra induced by gamma-irradiation of some dry medical herbs

Energy Technology Data Exchange (ETDEWEB)

Yordanov, N.D. [Laboratory EPR, Institute of Catalysis, Bulgarian Academy of Sciences, 1113 Sofia (Bulgaria)], E-mail: ndyepr@bas.bg; Lagunov, O. [Laboratory EPR, Institute of Catalysis, Bulgarian Academy of Sciences, 1113 Sofia (Bulgaria); Dimov, K. [Institute of Cryobiology and Food technology, 1162 Sofia (Bulgaria)

2009-04-15

The radiation-induced EPR spectra in some medical herbs are reported. The samples studied are: (i) leaves of nettle, common balm, peppermint and thyme; (ii) stalks of common balm, thyme, milfoil, yarrow and marigold; (iii) blossoms of yarrow and marigold; (iv) blossoms and leaves of hawthorn and tutsan; and (v) roots of common valerian, nettle, elecampane (black and white), restharrows and carlina. Before irradiation all samples exhibit one weak anisotropic singlet EPR line with effective g-value of 2.0050{+-}0.0002. The radiation-induced spectra fall into three groups. EPR spectra of irradiated blossoms of yarrow and marigold, stalks of common balm, thyme, tutsan and yarrow as well as roots of common valerian, nettle and elecampane (black and white) show 'cellulose-like' EPR spectrum typical for irradiated plants. It is characterized by one intense central line with g=2.0050{+-}0.0005 and two weak satellite lines situated ca. 30 G left and right to it. EPR spectra of gamma-irradiated restharrows and carlina are complex. They may be represented by one triplet corresponding to the 'cellulose-like' EPR spectrum, one relatively intense singlet, situated in the center of the spectrum, and five weak additional satellite lines left and right to the center. The last spectrum was assigned as 'carbohydrate-like' type. Only one intense EPR singlet with g=2.0048{+-}0.0005 was recorded after irradiation of leaves of nettle and common balm. The lifetime of the radiation-induced EPR spectra was followed for a period of 3 months.

Explanatory factors for evolution in air quality; Verklarende factoren voor evoluties in luchtkwaliteit

Energy Technology Data Exchange (ETDEWEB)

Deutsch, F.; Vankerkom, J.; Veldeman, N.; Peelaerts, W. [Unit Ruimtelijke Milieuaspecten, VITO, Mol (Belgium); Fierens, F.; Vanpoucke, C.; Trimpeneers, E. [Intergewestelijke Cel voor het Leefmilieu IRCEL, Vlaamse Milieumaatschappij Milieurapportering VMM, Brussels (Belgium); Vancraeynest, L.; Bossuyt, M. [Vlaamse Milieumaatschappij Milieurapportering MIRA, Mechelen (Belgium)

2010-12-15

aantal bijkomende Europese emissiereductiemaatregelen; (3) voor een emissiescenario met verdergaande emissiereducties. In de drie scenario's voor het jaar 2020 dalen in het algemeen de emissies en de concentraties. De veranderingen van de emissies zijn sector- en plaatsgebonden wat een invloed heeft op de relatieve sectorbijdragen voor Vlaanderen.

The simulated effects of wastewater-management actions on the hydrologic system and nitrogen-loading rates to wells and ecological receptors, Popponesset Bay Watershed, Cape Cod, Massachusetts

Science.gov (United States)

Walter, Donald A.

2013-01-01

Popponesset Bay watershed receive surface-water inflows: Shoestring Bay receives water from the Santuit River, and the tidal reach of the Mashpee River receives water (and associated nitrogen) from the nontidal reach of the Mashpee River. Much of the water discharging into these streams passes through ponds prior to discharge. The additional attenuation of nitrogen in groundwater that has passed through a pond and discharged into a stream prior to entering an estuary is about 3 kilograms per day. Advective-transport times in the aquifer generally are small—median traveltimes are about 4.5 years—and nitrogen loads at receptors respond quickly to wastewater-management actions. The simulated decreases in nitrogen loads were 50 and 80 percent of the total decreases within 5 and 15 years, respectively, after full sewering of the watershed and within 3 and 10 years, for sequential phases of partial sewering and disposal at WTFs. The results show that solute-transport models can be used to assess the responses of nitrogen loads to wastewater-management actions, and that loads at ecological receptors (receiving waters—ponds, streams or coastal waters—that support ecosystems) will respond within a few years to those actions. The responses vary for individual receptors as functions of hydrologic setting, traveltimes in the aquifer, and the unique set of nitrogen sources representing current and future wastewater-disposal actions within recharge areas. Changes in nitrogen loads from groundwater discharge to individual estuaries range from a decrease of 90 percent to an increase of 80 percent following sequential phases of hypothetical but realistic wastewater-management actions. The ability to explicitly represent the transport of mass through the aquifer allows for the evaluation of complex responses that include the effects of surface waters, traveltimes, and complex changes in sources. Most of the simulated decreases in nitrogen loads to Shoestring Bay and the tidal portion

Effect-directed fingerprints of 77 botanical extracts via a generic high-performance thin-layer chromatography method combined with assays and mass spectrometry.

Science.gov (United States)

Krüger, S; Hüsken, L; Fornasari, R; Scainelli, I; Morlock, G E

2017-12-22

Quantitative effect-directed profiles of 77 industrially and freshly extracted botanicals like herbs, spices, vegetables and fruits, widely used as food ingredients, dietary supplements or traditional medicine, gave relevant information on their quality. It allows the assessment of food, dietary supplements and phytomedicines with regard to potential health-promoting activities. In contrary to sum parameter assays and targeted analysis, chromatography combined with effect-directed analysis allows fast assignment of single active compounds and evaluation of their contribution to the overall activity, originating from a food or botanical sample. High-performance thin-layer chromatography was hyphenated with UV/Vis/FLD detection and effect-directed analysis, using the 2,2-diphenyl-1-picrylhydrazyl radical, Gram-negative Aliivibrio fischeri, Gram-positive Bacillus subtilis, acetylcholinesterase and tyrosinase assays. Bioactive compounds of interest were eluted using an elution head-based interface and further characterized by electrospray ionization (high-resolution) mass spectrometry. This highly streamlined workflow resulted in a hyphenated HPTLC-UV/Vis/FLD-EDA-ESI + /ESI - -(HR)MS method. The excellent quantification power of the method was shown on three compounds. For rosmarinic acid, contents ranged from 4.5mg/g (rooibos) to 32.6mg/g (rosemary), for kaempferol-3-glucoside from 0.6mg/g (caraway) to 4.4mg/g (wine leaves), and for quercetin-3-glucoside from 1.1mg/g (hawthorn leaves) to 17.7mg/g (thyme). Three mean repeatabilities (%RSD) over 18 quantifications for the three compounds were ≤2.2% and the mean intermediate precision over three different days (%RSD, n=3) was 5.2%. Copyright © 2017 Elsevier B.V. All rights reserved.

Quercetin Decreases Insulin Resistance in a Polycystic Ovary Syndrome Rat Model by Improving Inflammatory Microenvironment.

Science.gov (United States)

Wang, Zhenzhi; Zhai, Dongxia; Zhang, Danying; Bai, Lingling; Yao, Ruipin; Yu, Jin; Cheng, Wen; Yu, Chaoqin

2017-05-01

Insulin resistance (IR) is a clinical feature of polycystic ovary syndrome (PCOS). Quercetin, derived from Chinese medicinal herbs such as hawthorn, has been proven practical in the management of IR in diabetes. However, whether quercetin could decrease IR in PCOS is unknown. This study aims to observe the therapeutic effect of quercetin on IR in a PCOS rat model and explore the underlying mechanism. An IR PCOS rat model was established by subcutaneous injection with dehydroepiandrosterone. The body weight, estrous cycle, and ovary morphology of the quercetin-treated rats were observed. Serum inflammatory cytokines were analyzed using enzyme-linked immunosorbent assay. In ovarian tissues, the expression of key genes involved in the inflammatory signaling pathway was detected through Western blot, real-time polymerase chain reaction, or immunohistochemistry. The nuclear translocation of nuclear factor κB (NF-κB) was also observed by immunofluorescence. The estrous cycle recovery rate of the insulin-resistant PCOS model after quercetin treatment was 58.33%. Quercetin significantly reduced the levels of blood insulin, interleukin 1β, IL-6, and tumor necrosis factor α. Quercetin also significantly decreased the granulosa cell nuclear translocation of NF-κB in the insulin-resistant PCOS rat model. The treatment inhibited the expression of inflammation-related genes, including the nicotinamide adenine dinucleotide phosphate oxidase subunit p22phox, oxidized low-density lipoprotein, and Toll-like receptor 4, in ovarian tissue. Quercetin improved IR and demonstrated a favorable therapeutic effect on the PCOS rats. The underlying mechanism of quercetin potentially involves the inhibition of the Toll-like receptor/NF-κB signaling pathway and the improvement in the inflammatory microenvironment of the ovarian tissue of the PCOS rat model.

Does courtesy bias affect how clients report on objective and subjective measures of family planning service quality? A comparison between facility- and home-based interviews.

Science.gov (United States)

Hameed, Waqas; Ishaque, Muhammad; Gul, Xaher; Siddiqui, Junaid-Ur-Rehman; Hussain, Sharmeen; Hussain, Wajahat; Ahmed, Aftab; Balal, Asma

2017-01-01

Despite a general understanding that exit interviews being conducted at service providers' facilities may influence clients' responses favorably to health professionals, there is very little evidence available that demonstrates the extent to which this problem exists. This study aimed at assessing and comparing clients' perceptions of the quality of family planning services and their satisfaction levels between facility- and home-based interviews. A cross-sectional survey was conducted among clients receiving family planning services across three service delivery channels - nongovernmental organization (NGO) clinics, social franchise (SF) centers, and outreach camps. The survey took place from December 2015 to January 2016 in 70 districts across all four provinces of Pakistan. A total of 2,807 clients were interviewed, of whom 1,404 clients were interviewed at health facilities after receiving services and 1,403 were interviewed at their homes within 3 days of method uptake. Overall, we found no significant differences between the characteristics of study participants interviewed at health facilities or at home. The findings suggested that experiences reported in exit surveys at facilities were strongly biased positively. This was true for both experiential (service quality) and perception-based (satisfaction) questions in the context of SF centers, while at NGO clinics the interview location only affected clients' responses regarding service quality. However, in outreach settings, clients are more likely to share bad experiences in exit interviews than in home-based interviews on objectively asked questions (service quality). Our study indicates signs of courtesy bias and possibly the Hawthorne effect in exit interviews. Program implementers could opt for home-based interviews for women receiving services at NGO clinics or SF center, whereas exit interviews could be used in outreach settings.

Sequence-Stratigraphic Analysis of the Regional Observation Monitoring Program (ROMP) 29A Test Corehole and Its Relation to Carbonate Porosity and Regional Transmissivity in the Floridan Aquifer System, Highlands County, Florida

Science.gov (United States)

Ward, W. C.; Cunningham, K.J.; Renken, R.A.; Wacker, M.A.; Carlson, J.I.

2003-01-01

An analysis was made to describe and interpret the lithology of a part of the Upper Floridan aquifer penetrated by the Regional Observation Monitoring Program (ROMP) 29A test corehole in Highlands County, Florida. This information was integrated into a one-dimensional hydrostratigraphic model that delineates candidate flow zones and confining units in the context of sequence stratigraphy. Results from this test corehole will serve as a starting point to build a robust three-dimensional sequence-stratigraphic framework of the Floridan aquifer system. The ROMP 29A test corehole penetrated the Avon Park Formation, Ocala Limestone, Suwannee Limestone, and Hawthorn Group of middle Eocene to Pliocene age. The part of the Avon Park Formation penetrated in the ROMP 29A test corehole contains two composite depositional sequences. A transgressive systems tract and a highstand systems tract were interpreted for the upper composite sequence; however, only a highstand systems tract was interpreted for the lower composite sequence of the deeper Avon Park stratigraphic section. The composite depositional sequences are composed of at least five high-frequency depositional sequences. These sequences contain high-frequency cycle sets that are an amalgamation of vertically stacked high-frequency cycles. Three types of high-frequency cycles have been identified in the Avon Park Formation: peritidal, shallow subtidal, and deeper subtidal high-frequency cycles. The vertical distribution of carbonate-rock diffuse flow zones within the Avon Park Formation is heterogeneous. Porous vuggy intervals are less than 10 feet, and most are much thinner. The volumetric arrangement of the diffuse flow zones shows that most occur in the highstand systems tract of the lower composite sequence of the Avon Park Formation as compared to the upper composite sequence, which contains both a backstepping transgressive systems tract and a prograding highstand systems tract. Although the porous and permeable

霍桑的女权主义思想在海丝特·白兰个性上的体现%Hawthorne's Feminism Reflected in Hester's Personality

Institute of Scientific and Technical Information of China (English)

程树华

2001-01-01

文学评论界把女权主义思想定义为妇女对自身所处的社会、政治、经济地位的追求，而对女性自我保障、自我完善和自我发展意识强调甚少。实际上，霍桑的早期女权主义思想主要是从海丝特·白兰的自我保障意识上得以体现的。

Helical solutions of the bidirectional vortex in a cylindrical cyclone: Beltramian and Trkalian motions

International Nuclear Information System (INIS)

Majdalani, Joseph

2012-01-01

In this work, two families of helical motions are investigated as prospective candidates for describing the bidirectional vortex field in a right-cylindrical chamber. These basic solutions are relevant to cyclone separators and to idealized representations of vortex-fired liquid and hybrid rocket engines in which bidirectional vortex motion is established. To begin, the bulk fluid motion is taken to be isentropic along streamlines, with no concern for reactions, heat transfer, viscosity, compressibility or unsteadiness. Then using the Bragg–Hawthorne equation for steady, inviscid, axisymmetric motion, two families of Euler solutions are derived. Among the characteristics of the newly developed solutions one may note the axial dependence of the swirl velocity, the Trkalian and Beltramian types of the helical motions, the sensitivity of the solutions to the outlet radius, the alternate locations of the mantle, and the increased axial and radial velocity magnitudes, including the rate of mass transfer across the mantle, for which explicit approximations are obtained. Our results are compared to an existing, complex lamellar model of the bidirectional vortex in which the swirl velocity reduces to a free vortex. In this vein, we find the strictly Beltramian flows to share virtually identical pressure variations and radial pressure gradients with those associated with the complex lamellar motion. Furthermore, both families warrant an asymptotic treatment to overcome their endpoint limitations caused by their omission of viscous stresses. From a broader perspective, the work delineates a logical framework through which self-similar, axisymmetric solutions to bidirectional and multidirectional vortex motions may be pursued. It also illustrates the manner through which different formulations may be arrived at depending on the types of wall boundary conditions. For example, both the slip condition at the sidewall and the inlet flow pattern at the headwall may be enforced

Motivations for Botanical Use by Socioeconomically Diverse, Urban Adults: Does Evidence Support Motivation?

Science.gov (United States)

Duffy, Grace F; Shupe, Emily Stave; Kuczmarski, Marie Fanelli; Zonderman, Alan B; Evans, Michele K

2017-10-01

The study objectives were to characterize botanical dietary supplement (BDS) use and to compare the motivations for botanical supplement (BS) use to the efficacy of the botanical in a socioeconomically and racially diverse urban adult population. Subjects were from the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study, a 20-year prospective health disparities study with African American and white adults from Baltimore, Maryland. All study participants completed two dietary recalls and a dietary supplement (DS) questionnaire in Wave 3 (n = 2140). Diet quality was evaluated by the Healthy Eating Index-2010 and the Mean Adequacy Ratio for 17 micronutrients. A comparison of reported motivations to efficacy reported in the literature of single BS was conducted. Approximately 50% (1062/2140) of participants took DS. Of these, 8% (n = 178) reported taking either BS or BDS. It was found that BDS users had better diet quality than DS users as well as nonusers of DS. The top three motivations for BDS users were to improve overall health, to maintain health, and to supplement the diet. There is limited evidence for the efficacy of most BS. Review of the efficacy of the 15 BS reported by ≥5% of the study population revealed beneficial health roles for only fiber, gingko biloba extract EGb 761, and hawthorn berry. To the authors' knowledge, this study is the first to report a better quality diet with BDS use for a racially diverse urban population. Yet, improvement in diet is needed because overall quality did not achieve current recommendations. To improve overall health, it may be beneficial for this population to focus on dietary modifications to reduce the risks associated with chronic diseases. In general, the reported motivations for BS use were not supported by clinical evidence.

PRESENT-DAY GALACTIC EVOLUTION: LOW-METALLICITY, WARM, IONIZED GAS INFLOW ASSOCIATED WITH HIGH-VELOCITY CLOUD COMPLEX A

Energy Technology Data Exchange (ETDEWEB)

Barger, K. A.; Haffner, L. M.; Wakker, B. P.; Hill, Alex S. [Department of Astronomy, University of Wisconsin-Madison, Madison, WI 53706 (United States); Madsen, G. J. [Sydney Institute for Astronomy, School of Physics, University of Sydney, NSW 2006 (Australia); Duncan, A. K., E-mail: kbarger@astro.wisc.edu, E-mail: haffner@astro.wisc.edu, E-mail: Alex.Hill@csiro.au, E-mail: wakker@astro.wisc.edu, E-mail: greg.madsen@sydney.edu.au [Rose-Hulman Institute of Technology, Terre Haute, IN 47803 (United States)

2012-12-20

The high-velocity cloud Complex A is a probe of the physical conditions in the Galactic halo. The kinematics, morphology, distance, and metallicity of Complex A indicate that it represents new material that is accreting onto the Galaxy. We present Wisconsin H{alpha} Mapper kinematically resolved observations of Complex A over the velocity range of -250 to -50 km s{sup -1} in the local standard of rest reference frame. These observations include the first full H{alpha} intensity map of Complex A across (l, b) = (124 Degree-Sign , 18 Degree-Sign ) to (171 Degree-Sign , 53 Degree-Sign ) and deep targeted observations in H{alpha}, [S II] {lambda}6716, [N II] {lambda}6584, and [O I] {lambda}6300 toward regions with high H I column densities, background quasars, and stars. The H{alpha} data imply that the masses of neutral and ionized material in the cloud are similar, both being greater than 10{sup 6} M{sub Sun }. We find that the Bland-Hawthorn and Maloney model for the intensity of the ionizing radiation near the Milky Way is consistent with the known distance of the high-latitude part of Complex A and an assumed cloud geometry that puts the lower-latitude parts of the cloud at a distance of 7-8 kpc. This compatibility implies a 5% ionizing photon escape fraction from the Galactic disk. We also provide the nitrogen and sulfur upper abundance solutions for a series of temperatures, metallicities, and cloud configurations for purely photoionized gas; these solutions are consistent with the sub-solar abundances found by previous studies, especially for temperatures above 10{sup 4} K or for gas with a high fraction of singly ionized nitrogen and sulfur.

Health benefits of Tai Chi for older patients with type 2 diabetes: The “Move It for Diabetes Study” – A randomized controlled trial

Directory of Open Access Journals (Sweden)

Tracey Tsang

2007-10-01

Full Text Available Tracey Tsang1, Rhonda Orr1, Paul Lam2, Elizabeth J Comino3, Maria Fiatarone Singh11School of Exercise and Sport Science, Faculty of Health Sciences, University of Sydney, Lidcombe, NSW, Australia; 2School of Public Health and Community Medicine, University of New South Wales, Sydney, NSW, Australia; 3The University of NSW Research Centre for Primary Health Care and Equity, University of New South Wales, Sydney, NSW, AustraliaAbstract: Older adults with type 2 diabetes have mobility impairment and reduced fitness. This study aimed to test the efficacy of the “Tai Chi for Diabetes” form, developed to address health-related problems in diabetes, including mobility and physical function. Thirty-eight older adults with stable type 2 diabetes were randomized to Tai Chi or sham exercise, twice a week for 16 weeks. Outcomes included gait, balance, musculoskeletal and cardiovascular fitness, self-reported activity and quality of life. Static and dynamic balance index (−5.8 ± 14.2; p = 0.03 and maximal gait speed (6.2 ± 11.6%; p = 0.005 improved over time, with no significant group effects. There were no changes in other measures. Non-specific effects of exercise testing and/or study participation such as outcome expectation, socialization, the Hawthorne effect, or unmeasured changes in health status or compliance with medical treatment may underlie the modest improvements in gait and balance observed in this sham-exercise-controlled trial. This Tai Chi form, although developed specifically for diabetes, may not have been of sufficient intensity, frequency, or duration to effect positive changes in many aspects of physiology or health status relevant to older people with diabetes.Keywords: Tai Chi, Type 2 diabetes, physical function

Where heroes have to tread: spatialization in american fiction « Là où les héros doivent errer » : la spatialisation dans la fiction américaine

Directory of Open Access Journals (Sweden)

Salwa Karoui-Elounelli

2009-10-01

Full Text Available Le présent travail s’applique à explorer la rhétorique et la thématique de la spatialisation dans la fiction américaine en mettant l’accent sur le rôle constitutif que joue le mythe de la Frontière dans la vision esthétique du roman américain aussi bien de l’époque romantique que moderne, en insistant sur les manières dont ce même mythe se trouve redéfini et ré-informé à chacune de ces époques. A travers une analyse de l’articulation d’une vision de l’expérience américaine, en particulier de l’écriture elle-même dans The Scarlet Letter de Nathaniel Hawthorne, nous avons essayé, dans un premier temps, de circonscrire la manière dont l’imagerie spatiale ainsi que la représentation de l’espace traduisent l’expérience éthique et esthétique de la conquête de la Frontière, tout en annonçant la saturation à venir de l’idée de Frontière. L’œuvre de Scott Fitzgerald nous a permis, dans un deuxième temps, de dégager le caractère paradoxal du mythe de la Frontière. Le déploiement d’une rhétorique spatiale intense va de pair chez lui avec une vision esthétique qui finit par défaire le mythe de la Frontière jusqu’à l’épuisement. D’où la prédominance dans la littérature américaine moderne de l’idée d’une spatialité qui incarne la défaite.

Catharine Sedgwick’s Hope Leslie (1827 and the Revision of the Puritan Past

Directory of Open Access Journals (Sweden)

Teresa Requena Pelegrí

2009-06-01

Full Text Available Catharine Maria Sedgwick’s texts and achievement have been long overshadowed by the undisputed recognition of some of her male contemporaries. James Fenimore Cooper, Washington Irving or William Cullen Bryant have received all the credit for having shaped -and for many, created- U.S. literature. However, Sedgwick’s contribution to the development of a specific native tradition in American letters is undeniable. Long before Ralph Waldo Emerson’s call for a specifically national subject-matter, Sedgwick was consciously giving her texts an American perspective by combining the techniques used in sentimental fiction with the historical romance. Set in colonial times, Hope Leslie or Early Times in the Massachusetts (1827 constitutes one of Sedgwick’s poignant explorations of the Puritan past of the country and its interrelation with issues of gender and race. By fusing Puritan historical accounts with fiction, Sedgwick’s technique succeeds in foregrounding the partiality of historical accounts in opposition to their supposedly objective exposition of facts and in this way the text manages to challenge Puritan self-righteous historiography. Moreover, the use of the Puritan past as material for her fiction together with the inclusion of Native American characters makes Sedgwick an extremely interesting foil to other contemporaries such as Nathaniel Hawthorne or James Fenimore Cooper. This paper wishes to explore Sedgwick’s version of the Puritan presence in the American colonies and compare it with Nathaniel Hawthorne’s to demonstrate how the former made gender indistinguishable form the construction of a national narrative. The paper also tackles Sedgwick’s sexual and racial politics in her treatment of fully developed Native American characters thus constituting an enlightening counterpart to the stereotypical and reductive portrayal found in James Fenimore Cooper’s work.

Helical solutions of the bidirectional vortex in a cylindrical cyclone: Beltramian and Trkalian motions

Energy Technology Data Exchange (ETDEWEB)

Majdalani, Joseph, E-mail: joe.majdalani@gmail.com [Department of Mechanical, Aerospace and Biomedical Engineering, University of Tennessee Space Institute (UTSI), 411 B. H. Goethert Parkway, Tullahoma, TN 37388 (United States)

2012-10-15

In this work, two families of helical motions are investigated as prospective candidates for describing the bidirectional vortex field in a right-cylindrical chamber. These basic solutions are relevant to cyclone separators and to idealized representations of vortex-fired liquid and hybrid rocket engines in which bidirectional vortex motion is established. To begin, the bulk fluid motion is taken to be isentropic along streamlines, with no concern for reactions, heat transfer, viscosity, compressibility or unsteadiness. Then using the Bragg-Hawthorne equation for steady, inviscid, axisymmetric motion, two families of Euler solutions are derived. Among the characteristics of the newly developed solutions one may note the axial dependence of the swirl velocity, the Trkalian and Beltramian types of the helical motions, the sensitivity of the solutions to the outlet radius, the alternate locations of the mantle, and the increased axial and radial velocity magnitudes, including the rate of mass transfer across the mantle, for which explicit approximations are obtained. Our results are compared to an existing, complex lamellar model of the bidirectional vortex in which the swirl velocity reduces to a free vortex. In this vein, we find the strictly Beltramian flows to share virtually identical pressure variations and radial pressure gradients with those associated with the complex lamellar motion. Furthermore, both families warrant an asymptotic treatment to overcome their endpoint limitations caused by their omission of viscous stresses. From a broader perspective, the work delineates a logical framework through which self-similar, axisymmetric solutions to bidirectional and multidirectional vortex motions may be pursued. It also illustrates the manner through which different formulations may be arrived at depending on the types of wall boundary conditions. For example, both the slip condition at the sidewall and the inlet flow pattern at the headwall may be enforced or

The impact of pre-intervention rate of kidney function change on the assessment of CKD progression.

Science.gov (United States)

Fassett, Robert G; Geraghty, Dominic P; Coombes, Jeff S

2014-10-01

Without a run-in phase, chronic kidney disease (CKD) patients enrolled in clinical trials may not be identified as having progressive disease. The aim of this analysis was to quantify the effects of a run-in phase on kidney function outcome in CKD patients enrolled in the Lipid Lowering and Onset of Renal Disease (LORD) trial. The LORD trial assessed the effects of atorvastatin on the rate of change in the estimated glomerular filtration rate (eGFR) and included patients with serum creatinine 120 μmol/l. In this post hoc analysis, we assessed eGFR change during the 12-month period prior to enrolment, the 3-month run-in phase and the first 12-month period of the trial. Eighty of the original 132 patients (where retrospective data were available) were included. The rate of eGFR change during each period was compared. Overall kidney function decreased during the 12 months prior to enrolment by (mean, SD) 0.39 ± 0.98 ml/min/1.73 m(2)/month, improved during the 3-month run-in phase by 0.48 ± 2.90 ml/min/1.73 m(2)/month and decreased during the first 12 months of the trial by 0.15 ± 0.57 ml/min/1.73 m(2)/month. However, only 39 % of patients had declining eGFR during the 12 months prior, 19 % in the 3-month run-in and 42 % during the first 12-month study phase. Most patients (>60 %) entering this clinical trial had stable or improving kidney function. Enrolment was associated with further improved kidney function, which may have been due to 'regression to the mean' or to the Hawthorne effect. Investigators should include a run-in period to establish the presence of eGFR decline to use as an inclusion criterion in clinical trials assessing this measure of CKD progression.

Nutraceuticals and Dietary Supplements to Improve Quality of Life and Outcomes in Heart Failure Patients.

Science.gov (United States)

Cicero, Arrigo F G; Colletti, Alessandro

2017-01-01

Heart failure (HF) is a complex clinical syndrome that can result from any structural or functional cardiac disorder that impairs the ability of the ventricle to fill or eject blood. It represents a major public health issue, with a prevalence of over 23 million worldwide. The lifetime risk of developing HF is one in five and the most important risk factors identified are ischemic heart disease, hypertension, smoking, obesity and diabetes. Preventive approaches are based on improvements of lifestyle, associated with pharmacological therapy. Several nutraceuticals have shown interesting clinical results in prevention of HF as well as in the treatment of the early stages of the disease, alone or in association with pharmacological therapy. The aim of this review is to resume the available clinical evidence on phytochemicals effect on HF prevention and/or treatment. A systematic search strategy was developed to identify trials in PubMed (January 1980 to April 2016). The terms 'nutraceuticals', 'dietary supplements', 'herbal drug' and 'heart failure' were incorporated into an electronic search strategy. Clinical trials reported that the intake of some nutraceuticals (hawthorn, coenzyme Q10, L-carnitine, Dribose, Carnosine, Vitamin D, Some probiotics, Omega-3 PUFAs, Beet nitrates) is associated with improvements in functional parameters such as ejection fraction, stroke volume and cardiac output in HF patients, with minimal side effects. These findings were sometimes reinforced by subsequent meta-analyses, which further concluded that benefits tended to be greater in earlier stage HF. The main mechanisms involved are antioxidant, antinflammatory, anti-ischemic and antiaggregant effects. Evidence suggests that the supplementation with nutraceuticals may be a useful option for effective management of HF, with the advantage of excellent clinical tolerance. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Ambient Assistive Technologies (AAT: socio-technology as a powerful tool for facing the inevitable sociodemographic challenges?

Directory of Open Access Journals (Sweden)

Plischke Herbert

2010-06-01

Full Text Available Abstract Due to the socio-demographic change in most developed western countries, elderly populations have been continuously increasing. Therefore, preventive and assistive systems that allow elderly people to independently live in their own homes as long as possible will become an economical if not ethical necessity. These respective technologies are being developed under the term "Ambient Assistive Technologies" (AAT. The EU-funded AAT-project Ambient Lighting Assistance for an Ageing Population (ALADIN has established the long-term goal to create an adaptive system capable of improving the residential lighting conditions of single living elderly persons also aiming at supporting the preservation of their independence. Results of an earlier survey revealed that the elderly perceived their current lighting situation as satisfactory, whereas interviewers assessed in-house lighting as too dark and risk-laden. The overall results of ALADIN showed a significant increase in well-being from the baseline final testing with the new adaptive lighting system. Positive results for wellbeing and life quality suggest that the outcome effects may be attributed to the introduction of technology as well as to social contacts arising from participating in the study. The technological guidance of the study supervisors, in particular, may have produced a strong social reactivity effect that was first observed in the famous Hawthorne experiments in the 1930s. As older adults seem to benefit both from meaningful social contacts as well as assistive technologies, the question arises how assistive technology can be socially embedded to be able to maximize positive health effects. Therefore ethical guidelines for development and use of new assistive technologies for handicapped/older persons have to be developed and should be discussed with regard to their applicability in the context of AAT.

Crataegus Special Extract WS 1442 Effects on eNOS and microRNA 155.

Science.gov (United States)

Wang, Xinwen; Liang, Yan; Shi, Jian; Zhu, Hao-Jie; Bleske, Barry E

2018-04-16

Increased expression of microRNA 155 (miR-155) results in a decrease in endothelial nitric oxide synthase (eNOS) expression and impaired endothelial function. Factors that have been shown to increase expression of miR-155 may be mitigated by WS 1442, an extract of hawthorn leaves and flowers ( Crataegus special extract) that contains a range of pharmacologically active substances including oligomeric proanthocyanidins and flavonoids. The purpose of this study is to determine the effect of WS 1442 on the expression of miR-155 and eNOS in the presence of tumor necrosis factor (TNF- α ). Human umbilical vein endothelial cells (HUVECs) were studied after the exposure to TNF- α , with or without simvastatin (positive control) and WS 1442. The expression levels of eNOS, phosphorylated eNOS, and miR-155 in the different HUVEC treatment groups were determined by western blot and quantitative real-time polymerase chain reaction, respectively. To evaluate the effect of WS 1442 on the eNOS activity, the medium and intracellular nitrate/nitrite (NO) concentrations were also analyzed using a colorimetric Griess assay kit. The results demonstrated that TNF- α upregulated miR-155 expression and decreased eNOS expression and NO concentrations. WS 1442 also increased miR-155 expression and decreased eNOS expression but, unlike TNF- α , increased phosphorylated eNOS expression and NO concentrations. Surprisingly, WS 1442 increased miR-155 expression; however, WS 1442 mitigated the overall negative effect of miR-155 on decreasing eNOS expression by increasing expression of phosphorylated eNOS and resulting in an increase in NO concentrations. In the setting where miR-155 may be expressed, WS 1442 may offer vascular protection by increasing the expression of phosphorylated eNOS. Georg Thieme Verlag KG Stuttgart · New York.

Renal denervation after Symplicity HTN-3: an update.

Science.gov (United States)

Persu, Alexandre; Jin, Yu; Fadl Elmula, Fadl Elmula Mohamed; Jacobs, Lotte; Renkin, Jean; Kjeldsen, Sverre

2014-08-01

After three years of excessive confidence, overoptimistic expectations and performance of 15 to 20,000 renal denervation procedures in Europe, the failure of a single well-designed US trial--Symplicity HTN-3--to meet its primary efficacy endpoint has cast doubt on renal denervation as a whole. The use of a sound methodology, including randomisation and blinded endpoint assessment was enough to see the typical 25-30 mmHg systolic blood pressure decrease observed after renal denervation melt down to less than 3 mmHg, the rest being likely explained by Hawthorne and placebo effects, attenuation of white coat effect, regression to the mean and other physician and patient-related biases. The modest blood pressure benefit directly assignable to renal denervation should be balanced with unresolved safety issues, such as potentially increased risk of renal artery stenosis after the procedure (more than ten cases reported up to now, most of them in 2014), unclear long-term impact on renal function and lack of morbidity-mortality data. Accordingly, there is no doubt that renal denervation is not ready for clinical use. Still, renal denervation is supported by a strong rationale and is occasionally followed by major blood pressure responses in at-risk patients who may otherwise have remained uncontrolled. Upcoming research programmes should focus on identification of those few patients with truly resistant hypertension who may derive a substantial benefit from the technique, within the context of well-designed randomised trials and independent registries. While electrical stimulation of baroreceptors and other interventional treatments of hypertension are already "knocking at the door", the premature and uncontrolled dissemination of renal denervation should remain an example of what should not be done, and trigger radical changes in evaluation processes of new devices by national and European health authorities.

Zirconium, calcium, and strontium contents in magnesium based biodegradable alloys modulate the efficiency of implant-induced osseointegration

Directory of Open Access Journals (Sweden)

Mushahary D

2013-08-01

Full Text Available Dolly Mushahary,1,2 Ragamouni Sravanthi,2 Yuncang Li,2 Mahesh J Kumar,1 Nemani Harishankar,4 Peter D Hodgson,1 Cuie Wen,3 Gopal Pande2 1Institute for Frontier Materials, Deakin University, Geelong, Australia; 2CSIR- Centre for Cellular and Molecular Biology, Hyderabad, India; 3Faculty of Engineering and Industrial Sciences, Swinburne University of Technology, Hawthorn, Australia; 4National Institute of Nutrition (ICMR, Tarnaka, Hyderabad, India Abstract: Development of new biodegradable implants and devices is necessary to meet the increasing needs of regenerative orthopedic procedures. An important consideration while formulating new implant materials is that they should physicochemically and biologically mimic bone-like properties. In earlier studies, we have developed and characterized magnesium based biodegradable alloys, in particular magnesium-zirconium (Mg-Zr alloys. Here we have reported the biological properties of four Mg-Zr alloys containing different quantities of strontium or calcium. The alloys were implanted in small cavities made in femur bones of New Zealand White rabbits, and the quantitative and qualitative assessments of newly induced bone tissue were carried out. A total of 30 experimental animals, three for each implant type, were studied, and bone induction was assessed by histological, immunohistochemical and radiological methods; cavities in the femurs with no implants and observed for the same period of time were kept as controls. Our results showed that Mg-Zr alloys containing appropriate quantities of strontium were more efficient in inducing good quality mineralized bone than other alloys. Our results have been discussed in the context of physicochemical and biological properties of the alloys, and they could be very useful in determining the nature of future generations of biodegradable orthopedic implants. Keywords: osteoblasts, bone mineralization, corrosion, osseointegration, surface energy, peri-implant

Differences between urban and rural hedges in England revealed by a citizen science project.

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Gosling, Laura; Sparks, Tim H; Araya, Yoseph; Harvey, Martin; Ansine, Janice

2016-07-22

Hedges are both ecologically and culturally important and are a distinctive feature of the British landscape. However the overall length of hedges across Great Britain is decreasing. Current challenges in studying hedges relate to the dominance of research on rural, as opposed to urban, hedges, and their variability and geographical breadth. To help address these challenges and to educate the public on the importance of hedge habitats for wildlife, in 2010 the Open Air Laboratories (OPAL) programme coordinated a hedge-focused citizen science survey. Results from 2891 surveys were analysed. Woody plant species differed significantly between urban and rural areas. Beech, Holly, Ivy, Laurel, Privet and Yew were more commonly recorded in urban hedges whereas Blackthorn, Bramble, Dog Rose, Elder and Hawthorn were recorded more often in rural hedges. Urban and rural differences were shown for some groups of invertebrates. Ants, earwigs and shieldbugs were recorded more frequently in urban hedges whereas blowflies, caterpillars, harvestmen, other beetles, spiders and weevils were recorded more frequently in rural hedges. Spiders were the most frequently recorded invertebrate across all surveys. The presence of hard surfaces adjacent to the hedge was influential on hedge structure, number and diversity of plant species, amount of food available for wildlife and invertebrate number and diversity. In urban hedges with one adjacent hard surface, the food available for wildlife was significantly reduced and in rural hedges, one adjacent hard surface affected the diversity of invertebrates. This research highlights that urban hedges may be important habitats for wildlife and that hard surfaces may have an impact on both the number and diversity of plant species and the number and diversity of invertebrates. This study demonstrates that citizen science programmes that focus on hedge surveillance can work and have the added benefit of educating the public on the importance of

Is the use of antioxidants mixture ameliorating the double stress effect of radiation and hyperlipidaemia?

International Nuclear Information System (INIS)

Michael, M.I.; Amer, M.M.

2010-01-01

Radiation hazards, due to free radical generation, present an enormous challenge for biological and medical safety. In the same time, hyperlipidaemia represents one of the most important and recognized risk factor for atherosclerosis development as an event of accumulation of cells containing excess lipids within the arterial wall. Under normal physiological conditions, there is a critical balance in the generation of oxygen free radicals and antioxidant defense systems. In this study, we assumed that a subject encountered to both radiation and hyperlipidaemia oxidative stress and inquired if a mixture of three well known antioxidants can ameliorate this dramatically disorder. To answer the question, four groups of adult male albino rats were used; the control group (A) fed and drank ad libitum normal laboratory diet, the second group (B) fed normally and exposed to 5 Gy gamma radiation, the third group (C) fed high-fat diet (HFD) for two months then exposed to the same dose of radiation and the fourth group (D) subjected to the same treatment as group (C) and administrated a mixture of tryptophan (100 mg/kg b.w.), hawthorn extract (50 mg/100 g b.w.) and coenzyme Q10 (50 mg/kg b.w.) for one month. Body weight was recorded twice a week during the experimental period then all the animals were decapitated after one month and sera were collected to estimate total lipids, triglycerides, total cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), T3, T4, testosterone and corticosterone hormones besides glutathione. The results declared that radiation-hyperlipidaemia double stressors inadequately distorted the lipogram, hormonal and antioxidant status and the antioxidants mixture administrated could ameliorate these alterations and successfully brought back all the parameters investigated nearly to the control level.

Effect of single-dose Ginkgo biloba and Panax ginseng on driving performance.

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LaSala, Gregory S; McKeever, Rita G; Patel, Urvi; Okaneku, Jolene; Vearrier, David; Greenberg, Michael I

2015-02-01

Panax ginseng and Gingko biloba are commonly used herbal supplements in the United States that have been reported to increase alertness and cognitive function. The objective of this study was to investigate the effects of these specific herbals on driving performance. 30 volunteers were tested using the STISIM3® Driving Simulator (Systems Technology Inc., Hawthorne, CA, USA) in this double-blind, placebo-controlled study. The subjects were randomized into 3 groups of 10 subjects per group. After 10-min of simulated driving, subjects received either ginseng (1200 mg), Gingko (240 mg), or placebo administered orally. The test herbals and placebo were randomized and administered by a research assistant outside of the study to maintain blinding. One hour following administration of the herbals or placebo, the subjects completed an additional 10-min of simulated driving. Standard driving parameters were studied including reaction time, standard deviation of lateral positioning, and divided attention. Data collected for the divided attention parameter included time to response and number of correct responses. The data was analyzed with repeated-measures analysis of variance (ANOVA) and Kruskal-Wallis test using SPSS 22 (IBM, Armonk, NY, USA). There was no difference in reaction time or standard deviation of lateral positioning for both the ginseng and Ginkgo arms. For the divided attention parameter, the response time in the Ginkgo arm decreased from 2.9 to 2.5 s. The ginseng arm also decreased from 3.2 to 2.4 s. None of these values were statistically significant when between group differences were analyzed. The data suggests there was no statistically significant difference between ginseng, Ginkgo or placebo on driving performance. We postulate this is due to the relatively small numbers in our study. Further study with a larger sample size may be needed in order to elucidate more fully the effects of Ginkgo and ginseng on driving ability.

Does courtesy bias affect how clients report on objective and subjective measures of family planning service quality? A comparison between facility- and home-based interviews

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Hameed, Waqas; Ishaque, Muhammad; Gul, Xaher; Siddiqui, Junaid-ur-Rehman; Hussain, Sharmeen; Hussain, Wajahat; Ahmed, Aftab; Balal, Asma

2017-01-01

Purpose Despite a general understanding that exit interviews being conducted at service providers’ facilities may influence clients’ responses favorably to health professionals, there is very little evidence available that demonstrates the extent to which this problem exists. This study aimed at assessing and comparing clients’ perceptions of the quality of family planning services and their satisfaction levels between facility- and home-based interviews. Methods A cross-sectional survey was conducted among clients receiving family planning services across three service delivery channels – nongovernmental organization (NGO) clinics, social franchise (SF) centers, and outreach camps. The survey took place from December 2015 to January 2016 in 70 districts across all four provinces of Pakistan. A total of 2,807 clients were interviewed, of whom 1,404 clients were interviewed at health facilities after receiving services and 1,403 were interviewed at their homes within 3 days of method uptake. Results Overall, we found no significant differences between the characteristics of study participants interviewed at health facilities or at home. The findings suggested that experiences reported in exit surveys at facilities were strongly biased positively. This was true for both experiential (service quality) and perception-based (satisfaction) questions in the context of SF centers, while at NGO clinics the interview location only affected clients’ responses regarding service quality. However, in outreach settings, clients are more likely to share bad experiences in exit interviews than in home-based interviews on objectively asked questions (service quality). Conclusion Our study indicates signs of courtesy bias and possibly the Hawthorne effect in exit interviews. Program implementers could opt for home-based interviews for women receiving services at NGO clinics or SF center, whereas exit interviews could be used in outreach settings. PMID:29760573

Changes in composition, structure and aboveground biomass over seventy-six years (1930-2006) in the Black Rock Forest, Hudson Highlands, southeastern New York State.

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Schuster, W S F; Griffin, K L; Roth, H; Turnbull, M H; Whitehead, D; Tissue, D T

2008-04-01

We sought to quantify changes in tree species composition, forest structure and aboveground forest biomass (AGB) over 76 years (1930-2006) in the deciduous Black Rock Forest in southeastern New York, USA. We used data from periodic forest inventories, published floras and a set of eight long-term plots, along with species-specific allometric equations to estimate AGB and carbon content. Between the early 1930s and 2000, three species were extirpated from the forest (American elm (Ulmus americana L.), paper birch (Betula papyrifera Marsh.) and black spruce (Picea mariana (nigra) (Mill.) BSP)) and seven species invaded the forest (non-natives tree-of-heaven (Ailanthus altissima (Mill.) Swingle) and white poplar (Populus alba L.) and native, generally southerly distributed, southern catalpa (Catalpa bignonioides Walt.), cockspur hawthorn (Crataegus crus-galli L.), red mulberry (Morus rubra L.), eastern cottonwood (Populus deltoides Bartr.) and slippery elm (Ulmus rubra Muhl.)). Forest canopy was dominated by red oak and chestnut oak, but the understory tree community changed substantially from mixed oak-maple to red maple-black birch. Density decreased from an average of 1500 to 735 trees ha(-1), whereas basal area doubled from less than 15 m(2) ha(-1) to almost 30 m(2) ha(-1) by 2000. Forest-wide mean AGB from inventory data increased from about 71 Mg ha(-1) in 1930 to about 145 Mg ha(-1) in 1985, and mean AGB on the long-term plots increased from 75 Mg ha(-1) in 1936 to 218 Mg ha(-1) in 1998. Over 76 years, red oak (Quercus rubra L.) canopy trees stored carbon at about twice the rate of similar-sized canopy trees of other species. However, there has been a significant loss of live tree biomass as a result of canopy tree mortality since 1999. Important constraints on long-term biomass increment have included insect outbreaks and droughts.

Fluctuating attentional demand in a simulated driving assessment: the roles of age and driving complexity.

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Stinchcombe, Arne; Gagnon, Sylvain; Zhang, J Jane; Montembeault, Patricia; Bedard, Michel

2011-12-01

The purpose of the study was to explore age differences in attentional demand in response to driving situations of varying complexity within the context of a simulated assessment protocol. It was hypothesized that as road complexity increased, an indicator of attentional demand (i.e., latency to respond to a secondary task) would increase and, independent of the road complexity, older adults would exhibit greater attentional demand in comparison with younger and middle-aged drivers. Drivers from 3 age categories (i.e., young, middle-aged, and older) completed an assessment protocol in a STISIM driving simulator (Systems Technology, Inc., Hawthorne, CA) during which participants responded to a series of strategically placed secondary tasks (i.e., peripheral detection tasks, PDTs). Situations where secondary tasks occurred were grouped according to whether they were straight-road, crossing-path, or lane-change events. Two global indices of driving safety as well as several cognitive measures external to the driving simulator were also collected. The results supported the hypothesis in that complex driving situations elicited greater attentional demand among drivers of all ages. Older adults showed greater attentional demand in comparison to young and middle-aged adults even after controlling for baseline response time. Older drivers also scored poorer on a global measure of driving safety. The findings are highly consistent with the literature on road complexity and attention that show that increased driving complexity is associated with poorer performance on tasks designed to concurrently assess attention, an effect that is more pronounced for older drivers. The results point to intrinsic and extrinsic factors that contribute to motor vehicle collisions (MVCs) among older drivers. The relevance of these findings is discussed in relation to interventions and future research aimed at improving road safety.

Using direct clinical observation to assess the quality of cesarean delivery in Afghanistan: an exploratory study

Science.gov (United States)

2014-01-01

of providers and facilities and detect potential Hawthorne effects. PMID:24886143

The cost of community-managed viral respiratory illnesses in a cohort of healthy preschool-aged children

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Allen Kelly M

2008-01-01

Full Text Available Abstract Background Acute respiratory illnesses (ARIs during childhood are often caused by respiratory viruses, result in significant morbidity, and have associated costs for families and society. Despite their ubiquity, there is a lack of interdisciplinary epidemiologic and economic research that has collected primary impact data, particularly associated with indirect costs, from families during ARIs in children. Methods We conducted a 12-month cohort study in 234 preschool children with impact diary recording and PCR testing of nose-throat swabs for viruses during an ARI. We used applied values to estimate a virus-specific mean cost of ARIs. Results Impact diaries were available for 72% (523/725 of community-managed illnesses between January 2003 and January 2004. The mean cost of ARIs was AU$309 (95% confidence interval $263 to $354. Influenza illnesses had a mean cost of $904, compared with RSV, $304, the next most expensive single-virus illness, although confidence intervals overlapped. Mean carer time away from usual activity per day was two hours for influenza ARIs and between 30 and 45 minutes for all other ARI categories. Conclusion From a societal perspective, community-managed ARIs are a significant cost burden on families and society. The point estimate of the mean cost of community-managed influenza illnesses in healthy preschool aged children is three times greater than those illnesses caused by RSV and other respiratory viruses. Indirect costs, particularly carer time away from usual activity, are the key cost drivers for ARIs in children. The use of parent-collected specimens may enhance ARI surveillance and reduce any potential Hawthorne effect caused by compliance with study procedures. These findings reinforce the need for further integrated epidemiologic and economic research of ARIs in children to allow for comprehensive cost-effectiveness assessments of preventive and therapeutic options.

Pain Assessment in Impaired Cognition (PAIC: content validity of the Dutch version of a new and universal tool to measure pain in dementia

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van Dalen-Kok AH

2017-12-01

Full Text Available Annelore H van Dalen-Kok,1 Wilco P Achterberg,1 Wieke E Rijkmans,1 Sara A Tukker-van Vuuren,1 Suzanne Delwel,2,3 Henrica CW de Vet,4 Frank Lobbezoo,2,5 Margot WM de Waal1 1Department of Public Health and Primary Care, Leiden University Medical Centre, Leiden, 2Department of Oral Kinesiology, Academic Centre for Dentistry Amsterdam (ACTA, University of Amsterdam and VU University Amsterdam, 3Department of Clinical Neuropsychology, Faculty of Behavioral and Movement Sciences, VU University, 4Department of Epidemiology and Biostatistics, The EMGO Institute for Health and Care Research, VU University Medical Center, 5MOVE Research Institute Amsterdam, VU University, Amsterdam, the Netherlands Objectives: Detection and measurement of pain in persons with dementia by using observational pain measurement tools is essential. However, the evidence for the psychometric properties of existing observational tools remains limited. Therefore, a new meta-tool has been developed: Pain Assessment in Impaired Cognition (PAIC, as a collaborative EU action. The aim is to describe the translation procedure and content validity of the Dutch version of the PAIC.Methods: Translation of the PAIC into Dutch followed the forward-backward approach of the Guidelines for Establishing Cultural Equivalence of Instruments. A questionnaire survey was administered to clinical nursing home experts (20 physicians and 20 nurses to determine whether the PAIC items are indicative of pain and whether items are specific for pain or for other disorders (anxiety disorder, delirium, dementia, or depression. To quantify content validity, mean scores per item were calculated.Results: Eleven items were indicative of pain, for example, “frowning,” “freezing,” and “groaning.” Fifteen items were considered to be pain-specific, for example, “frowning,” “curling up,” and “complaining.” There were discrepancies between the notion of pain characteristics according to nurses

Developing a postglacial rockfall chronology in the mountainous fjord landscape of western Norway

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Laute, Katja; Beylich, Achim A.; Winkler, Stefan

2015-04-01

Large areas of glacially sculpted mountain landscapes worldwide exhibit a high spatial density of postglacial rockfalls and rock-slope failures. However, the temporal patterns of rock-slope failure frequencies after Deglaciation are still fairly unknown. The mountainous fjord landscape in western Norway represents a suitable study area as it exhibits a high number of rockfalls and rock-slope failures within a region with a well known Deglaciation history. Two steep, parabolic-shaped and glacier-connected neighbouring drainage basins, Erdalen (79.5 km2) and Bødalen (60.1 km2), located on the western side of the Jostedalsbreen ice cap in western Norway are selected as study areas. The focus of this study is on (i) the temporal reconstruction of rockfalls and rock-slope failures within the two defined and nearly lithologically homogenous study areas and (ii) the identification and explanation of possible triggering and controlling factors of the investigated rock-slope failures. First investigations have started by applying Schmidt-hammer exposure-age dating (SHD) at seven larger rockfall deposits as well as at five moraines of known age within both study areas. During the sampling 50 to 100 impacts using a mechanical Proceq N-type instrument were taken from the surface of 5 to 50 single rockfall boulders located at the outer margin of the rockfall deposits. In order to avoid sampling of more recent rockfalls or redistributed debris material the sampling strategy selected preferred a larger number of individual boulders sampled with few impacts over sampling just a small number of boulders with a high number of multiple impacts. First results show that the mean rebound (R-) values measured at the seven rockfall deposits fall into recognizably different age categories. Based on the SHD measurements obtained from the moraines of known age, the determined rockfall age categories are situated between the Preboral and Little Ice Age period. The chronology and possible

Toxicity of lead-contaminated sediment to mallards

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Heinz, G.H.; Hoffman, D.J.; Sileo, L.; Audet, D.J.; LeCaptain, L.J.

1999-01-01

Because consumption of lead-contaminated sediment has been suspected as the cause of waterfowl mortality in the Coeur d?Alene River basin in Idaho, we studied the bioavailability and toxicity of this sediment to mallards (Anas platyrhynchos). In experiment 1, one of 10 adult male mallards died when fed a pelleted commercial duck diet that contained 24% lead-contaminated sediment (with 3,400 μg/g lead in the sediment). Protoporphyrin levels in the blood increased as the percentage of lead-contaminated sediment in the diet increased. Birds fed 24% lead-contaminated sediment exhibited atrophy of the breast muscles, green staining of the feathers around the vent, viscous bile, green staining of the gizzard lining, and renal tubular intranuclear inclusion bodies. Mallards fed 24% lead-contaminated sediment had means of 6.1 μg/g of lead in the blood and 28 μg/g in the liver (wet-weight basis) and 1,660 μg/g in the feces (dry-weight basis). In experiment 2, we raised the dietary concentration of the lead-contaminated sediment to 48%, but only about 20% sediment was actually ingested due to food washing by the birds. Protoporphyrin levels were elevated in the lead-exposed birds, and all of the mallards fed 48% lead-contaminated sediment had renal tubular intranuclear inclusion bodies. The concentrations of lead in the liver were 9.1 μg/g for mallards fed 24% lead-contaminated sediment and 16 μg/g for mallards fed 48% lead-contaminated sediment. In experiment 3, four of five mallards died when fed a ground corn diet containing 24% lead-contaminated sediment (with 4,000 μg/g lead in this sample of sediment), but none died when the 24% lead-contaminated sediment was mixed into a nutritionally balanced commercial duck diet; estimated actual ingestion rates for sediment were 14% and 17% for the corn and commercial diets. Lead exposure caused elevations in protoporphyrin, and four of the five mallards fed 24% lead-contaminated sediment in a commercial diet and all five

Ground-water hydrology and simulation of ground-water flow at Operable Unit 3 and surrounding region, U.S. Naval Air Station, Jacksonville, Florida

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Davis, J.H.

1998-01-01

The Naval Air Station, Jacksonville (herein referred to as the Station), occupies 3,800 acres adjacent to the St. Johns River in Duval County, Florida. Operable Unit 3 (OU3) occupies 134 acres on the eastern side of the Station and has been used for industrial and commercial purposes since World War II. Ground water contaminated by chlorinated organic compounds has been detected in the surficial aquifer at OU3. The U.S. Navy and U.S. Geological Survey (USGS) conducted a cooperative hydrologic study to evaluate the potential for ground water discharge to the neighboring St. Johns River. A ground-water flow model, previously developed for the area, was recalibrated for use in this study. At the Station, the surficial aquifer is exposed at land surface and forms the uppermost permeable unit. The aquifer ranges in thickness from 30 to 100 feet and consists of unconsolidated silty sands interbedded with local beds of clay. The low-permeability clays of the Hawthorn Group form the base of the aquifer. The USGS previously conducted a ground-water investigation at the Station that included the development and calibration of a 1-layer regional ground-water flow model. For this investigation, the regional model was recalibrated using additional data collected after the original calibration. The recalibrated model was then used to establish the boundaries for a smaller subregional model roughly centered on OU3. Within the subregional model, the surficial aquifer is composed of distinct upper and intermediate layers. The upper layer extends from land surface to a depth of approximately 15 feet below sea level; the intermediate layer extends from the upper layer down to the top of the Hawthorn Group. In the northern and central parts of OU3, the upper and intermediate layers are separated by a low-permeability clay layer. Horizontal hydraulic conductivities in the upper layer, determined from aquifer tests, range from 0.19 to 3.8 feet per day. The horizontal hydraulic

Pain management in patients with dementia

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Achterberg WP

2013-11-01

Full Text Available Wilco P Achterberg,1 Marjoleine JC Pieper,2 Annelore H van Dalen-Kok,1 Margot WM de Waal,1 Bettina S Husebo,3 Stefan Lautenbacher,4 Miriam Kunz,4 Erik JA Scherder,5 Anne Corbett6 1Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, 2Department of General Practice and Elderly Care Medicine, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; 3Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway; 4Physiological Psychology, Otto Friedrich University Bamberg, Bamberg, Germany; 5Department of Clinical Neuropsychology, VU University Amsterdam, Amsterdam, The Netherlands; 6Wolfson Centre for Age-Related Diseases, King's College London, London, UK Abstract: There are an estimated 35 million people with dementia across the world, of whom 50% experience regular pain. Despite this, current assessment and treatment of pain in this patient group are inadequate. In addition to the discomfort and distress caused by pain, it is frequently the underlying cause of behavioral symptoms, which can lead to inappropriate treatment with antipsychotic medications. Pain also contributes to further complications in treatment and care. This review explores four key perspectives of pain management in dementia and makes recommendations for practice and research. The first perspective discussed is the considerable uncertainty within the literature on the impact of dementia neuropathology on pain perception and processing in Alzheimer's disease and other dementias, where white matter lesions and brain atrophy appear to influence the neurobiology of pain. The second perspective considers the assessment of pain in dementia. This is challenging, particularly because of the limited capacity of self-report by these individuals, which means that assessment relies in large part on observational methods. A number of tools are available but the psychometric quality and clinical utility of these are

Using Case Studies to Teach Interdisciplinary Water Resource Sustainability

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Orr, C. H.; Tillotson, K.

2012-12-01

Teaching about water resources and often emphasizes the biophysical sciences to understand highly complex hydrologic, ecologic and engineering systems, yet most impediments to improving management emerge from social processes. Challenges to more sustainable management often result from trade-offs among stakeholders (e.g., ecosystem services, energy, municipal use, and agriculture) and occur while allocating resources to competing goals of economic development, social equity, and efficient governance. Competing interests operating across multiple scales can increase tensions and prevent collaborative resolution of resource management problems. Here we discuss using specific, place-based cases to teach the interdisciplinary context of water management. Using a case approach allows instructors to first explore the geologic and hydrologic setting of a specific problem to let students understand where water comes from, then how it is used by people and ecosystems, and finally what conflicts arise from mismatches between water quality, quantity, timing, human demand, and ecosystem needs. The case approach helps students focus on specific problem to understand how the landscape influences water availability, without needing to first learn everything about the relevant fields. We look at geology, hydrology and climate in specific watersheds before addressing the human and ecosystem aspects of the broader, integrated system. This gives students the context to understand what limits water availability and how a water budget constrains possible solutions to sustainability problems. It also mimics the approach we have taken in research addressing these problems. In an example case the Spokane Coeur D'Alene basin, spanning the border between SE Washington and NW Idaho, includes a sole source aquifer system with high exchange between surface water and a highly conductive aquifer. The Spokane River does not meet water quality standards and is likely to face climate driven shifts

Application of Landsat 5-TM and GIS data to elk habitat studies in northern Idaho

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Hayes, Stephen Gordon

1999-12-01

An extensive geographic information system (GIS) database and a large radiotelemetry sample of elk (n = 153) were used to study habitat use and selection differences between cow and bull elk (Cervus elaphus) in the Coeur d'Alene Mountains of Idaho. Significant sex differences in 40 ha area use, and interactive effects of sex and season on selection of 40 ha areas from home ranges were found. In all seasons, bulls used habitats with more closed canopy forest, more hiding cover, and less shrub and graminoid cover, than cows. Cows selected areas with shrub and graminoid cover in winter and avoided areas with closed canopy forest and hiding cover in winter and summer seasons. Both sexes selected 40 ha areas of unfragmented hiding cover and closed canopy forest during the hunting season. Bulls also avoided areas with high open road densities during the rut and hunting season. These results support present elk management recommendations, but our observations of sexual segregation provide biologists with an opportunity to refine habitat management plans to target bulls and cows specifically. Furthermore, the results demonstrate that hiding cover and canopy closure can be accurately estimated from Landsat 5-TM imagery and GIS soil data at a scale and resolution to which elk respond. As a result, our habitat mapping methods can be applied to large areas of private and public land with consistent, cost-efficient results. Non-Lambertian correction models of Landsat 5-TM imagery were compared to an uncorrected image to determine if topographic normalization increased the accuracy of elk habitat maps of forest structure in northern Idaho. The non-Lambertian models produced elk habitat maps with overall and kappa statistic accuracies as much as 21.3% higher (p < 0.0192) than the uncorrected image. Log-linear models and power analysis were used to study the dependence of commission and omission error rates on topographic normalization, vegetation type, and solar incidence angle

Does courtesy bias affect how clients report on objective and subjective measures of family planning service quality? A comparison between facility- and home-based interviews

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Hameed W

2018-05-01

Full Text Available Waqas Hameed, Muhammad Ishaque, Xaher Gul, Junaid-ur-Rehman Siddiqui, Sharmeen Hussain, Wajahat Hussain, Aftab Ahmed, Asma Balal Strategy Department, Marie Stopes Society, Karachi, Sindh, Pakistan Purpose: Despite a general understanding that exit interviews being conducted at service providers’ facilities may influence clients’ responses favorably to health professionals, there is very little evidence available that demonstrates the extent to which this problem exists. This study aimed at assessing and comparing clients’ perceptions of the quality of family planning services and their satisfaction levels between facility- and home-based interviews. Methods: A cross-sectional survey was conducted among clients receiving family planning services across three service delivery channels – nongovernmental organization (NGO clinics, social franchise (SF centers, and outreach camps. The survey took place from December 2015 to January 2016 in 70 districts across all four provinces of Pakistan. A total of 2,807 clients were interviewed, of whom 1,404 clients were interviewed at health facilities after receiving services and 1,403 were interviewed at their homes within 3 days of method uptake. Results: Overall, we found no significant differences between the characteristics of study participants interviewed at health facilities or at home. The findings suggested that experiences reported in exit surveys at facilities were strongly biased positively. This was true for both experiential (service quality and perception-based (satisfaction questions in the context of SF centers, while at NGO clinics the interview location only affected clients’ responses regarding service quality. However, in outreach settings, clients are more likely to share bad experiences in exit interviews than in home-based interviews on objectively asked questions (service quality. Conclusion: Our study indicates signs of courtesy bias and possibly the Hawthorne effect in

An extract of Crataegus pinnatifida fruit attenuates airway inflammation by modulation of matrix metalloproteinase-9 in ovalbumin induced asthma.

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In Sik Shin

Full Text Available BACKGROUND: Crataegus pinnatifida (Chinese hawthorn has long been used as a herbal medicine in Asia and Europe. It has been used for the treatment of various cardiovascular diseases such as myocardial weakness, tachycardia, hypertension and arteriosclerosis. In this study, we investigated the anti-inflammatory effects of Crataegus pinnatifida ethanolic extracts (CPEE on Th2-type cytokines, eosinophil infiltration, expression of matrix metalloproteinase (MMP-9, and other factors, using an ovalbumin (OVA-induced murine asthma model. METHODS/PRINCIPAL FINDING: Airways of OVA-sensitized mice exposed to OVA challenge developed eosinophilia, mucus hypersecretion and increased cytokine levels. CPEE was applied 1 h prior to OVA challenge. Mice were administered CPEE orally at doses of 100 and 200 mg/kg once daily on days 18-23. Bronchoalveolar lavage fluid (BALF was collected 48 h after the final OVA challenge. Levels of interleukin (IL-4 and IL-5 in BALF were measured using enzyme-linked immunosorbent (ELISA assays. Lung tissue sections 4 µm in thickness were stained with Mayer's hematoxylin and eosin for assessment of cell infiltration and mucus production with PAS staining, in conjunction with ELISA, and Western blot analyses for the expression of MMP-9, intercellular adhesion molecule (ICAM-1 and vascular cell adhesion molecule (VCAM-1 protein expression. CPEE significantly decreased the Th2 cytokines including IL-4 and IL-5 levels, reduced the number of inflammatory cells in BALF and airway hyperresponsiveness, suppressed the infiltration of eosinophil-rich inflammatory cells and mucus hypersecretion and reduced the expression of ICAM-1, VCAM-1 and MMP-9 and the activity of MMP-9 in lung tissue of OVA-challenged mice. CONCLUSIONS: These results showed that CPEE can protect against allergic airway inflammation and can act as an MMP-9 modulator to induce a reduction in ICAM-1 and VCAM-1 expression. In conclusion, we strongly suggest the feasibility

The use of fruit extracts for production of beverages with high antioxidative activity

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Tomasz Tarko

2015-08-01

Full Text Available Free radicals and reactive oxygen species can cause many diseases of the circulatory and nervous system as well as tumors. There are many ways of preventing and treating these diseases including the consumption of products that contain significant amounts of antioxidant compounds, such as polyphenols and antioxidative vitamins. However, currently food stores offer mainly convenient food, ready-to-eat foodstuffs or highly processed products. During numerous technological treatments they have been deprived of many valuable compounds occurring in fresh products. Therefore, an important element of the food production technology is to ensure a proper composition of valuable human health-promoting compounds, mostly vitamins, minerals and polyphenols in final food product. Consumers often and willingly drink beverages. They are also a good starting base for supplementation. Drinks can be enriched with polyphenols, which may reduce the risk of lifestyle diseases, owing to their antiradical potential. The aim of this study was to use the fruit extracts for beverages enrichment in order to increase their antioxidative potential and polyphenol content. For the experiment the fruits of Cornelian cherry, lingonberry, elderberry, hawthorn and Japanese quince were used. Fruit was extracted with 80% ethanol, and then thickened by distillation under reduced pressure. Extracts were used to enrich the apple, orange and grapefruit beverages. Antioxidative activity and total polyphenols content in final beverages were determined. Also, sensory analysis was carried out. The fortification of tested beverages resulted in an increased antioxidative activity and total polyphenol content in case of all applied fruit extracts. Among the beverages composed, the best antioxidative properties were found in a beverage of red grapefruit, whereas the best organoleptically evaluated was the orange beverage. The scores of on the sensory evaluation revealed that the addition of

Suitability of thermoluminescence, chemiluminescence, ESR and viscosity measurements as detection method for the irradiation of medicinal herbs; Eignung von Thermolumineszenz-, Chemilumineszenz-, ESR- und Viskositaetsmessungen zur Identifizierung strahlenbehandelter Arzneidrogen

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Schuettler, C.; Gebhardt, G.; Stock, A.; Helle, N.; Boegl, K.W.

1993-12-31

Chemiluminescence, electron spin resonance, thermoluminescence and viscosity measurements have been investigated for their suitability as detection method for the irradiation of the medicinal herbs anise seeds (anisi fructus), valerian roots (valerianae radix), redberry leaves (uvae ursi folium), birch leaves (betulae folium), greek hay seeds (foenugraeci semen), cayenne pepper (capsici fructus acer), black-aldertee bark (frangulae cortex), fennel fruits (feoniculi fructus), rose hip shells (cynosbati fructus), coltsfoot (farfarae folium), acorus roots (calami rhizoma), chamomile flowers (matricariae flos), caraway (carvi fructus), lavender flowers (lavandulae flos), linseed (lini semen), lime tree flowers (tiliae flos), St. Mary`s thistle fruit (cardui mariae herba), lemon balm (melissae folium), java tea (orthosiphonis folium), peppermint (menthae piperitae folium), sage leaves (salviae folium), scouring rush (equiseti herba), senna leaves (sennae folium), plantain herbs (plantaginis lanceolata herba), thyme herbs (thymi herba), juniper berries (juniperi fructus), hawthorne herbs (crataegi folium), wheat starch (amylum tritici) and wormwood (absinthii herba). Depending on the herbs, the methods used were more or less suitable. Chemiluminescence measurements showed the smallest differences between untreated and irradiated samples whereas thermoluminescence measurements on isolated minerals from the vegetable drugs gave better results. In some herbs radiation-specific radicals could be identified by ESR spectroscopy. Viscosity measurement is suitable for some herbs as fast and inexpensive method for screening. (orig.) [Deutsch] Die Eignung von Chemilumineszenz-, ESR-, Thermolumineszenz- und Viskositaetsmessungen als Nachweismethode fuer die Behandlung von Arzneidrogen mit ionisierenden Strahlen wurde an Anis, Baldrianwurzel, Baerentraubenblaettern, Birkenblaettern, Bockshornsamen, Cayennepfeffer, Faulbaumrinde, Fenchel, Hagebuttenschalen, Huflattichblaettern

[Is DRG Coding too Important to be Left to Physicians? - Evaluation of Economic Efficiency by Health Economists in a University Medical Centre].

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Burger, F; Walgenbach, M; Göbel, P; Parbs, S; Neugebauer, E

2017-04-01

Background: We investigated and evaluated the cost effectiveness of coding by health care economists in a centre for orthopaedics and trauma surgery in Germany, by quantifying and comparing the financial efficiency of physicians with basic knowledge of the DRG-system with the results of healthcare economists with in-depth knowledge (M.Sc.). In addition, a hospital survey was performed to establish how DRG-coding is being performed and the identity of the persons involved. Material and Methods: In a prospective and controlled study, 200 in-patients were coded by a healthcare economist (study group). Prior to that, the same cases were coded by physicians with basic training in the DRG-system, who made up the control group. All cases were picked randomly and blinded without informing the physicians coding the controls, in order to avoid any Hawthorne effect. We evaluated and measured the effective weighting within the G-DRG, the DRG returns per patient, the overall DRG return, and the additional time needed. For the survey, questionnaires were sent to 1200 German hospitals. The completed questionnaire was analysed using a statistical program. Results: The return difference per patient between controls and the study group was significantly greater (2472 ± 337 €; p DRG case reports was 1277 (2500-62,300). Coding was performed in 69 % of cases by doctors, 19 % by skilled specialists for DRG coding and in 8 % together. Overall satisfaction with the DRG was described by 61 % of respondents as good or excellent. Conclusion: Our prospective and controlled study quantifies the cost efficiency of health economists in a centre of orthopaedics and trauma surgery in Germany for the first time. We provide some initial evidence that health economists can enhance the CMI, the resulting DRG return per patient as well as the overall DRG return. Data from the survey shows that in many hospitals there is great reluctance to leave the coding to specialists only. Georg

Design, rationale, and baseline demographics of SEARCH I: a prospective cluster-randomized study

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Albers F

2012-07-01

Full Text Available Frank Albers,1 Asif Shaikh,2 Ahmar Iqbal,31Medical Affairs Respiratory, 2Clinical Development and Medical Affairs, Field Based Medicine-Respiratory, Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT, USA; 3Respiratory Medical Affairs, Pfizer Inc, New York, NY, USAAbstract: Questionnaires are available to identify patients at risk for several chronic diseases, including COPD, but are infrequently utilized in primary care. COPD is often underdiagnosed, while at the same time the US Preventive Services Task Force recommends against spirometric screening for COPD in asymptomatic adults. Use of a symptom-based questionnaire and subsequent handheld spirometric device depending on the answers to the questionnaire is a promising approach to identify patients at risk for COPD. Screening, Evaluating and Assessing Rate CHanges of diagnosing respiratory conditions in primary care 1 (SEARCH I was a prospective cluster-randomized study in 168 US primary care practices evaluating the effect of the COPD-Population Screener (COPD-PS™ questionnaire. The effect of this questionnaire alone or sequentially with the handheld copd-6TM device was evaluated on new diagnoses of COPD and on respiratory diagnostic practice patterns (including referrals for pulmonary function testing, referrals to pulmonologists, new diagnoses of COPD, and new respiratory medication prescriptions. Participating practices entered a total of 9704 consecutive consenting subjects aged ≥ 40 years attending primary care clinics. Study arm results were compared for new COPD diagnosis rates between usual care and (1 COPD-PS plus copd-6 and (2 COPD-PS alone. A cluster-randomization design allowed comparison of the intervention effects at the practice level instead of individuals being the subjects of the intervention. Regional principal investigators controlled the flow of study information to sub-investigators at participating practices to reduce observation bias (Hawthorne effect. The

Use of Tritium and Helium to Define Groundwater Flow Conditions in a Coastal Aquifer Influenced by Seawater Intrusion: Everglades National Park

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Price, R. M.; Top, Z.; Happell, J. D.; Swart, P. K.

2002-05-01

The concentrations of tritium (3H) and helium isotopes (3He, 4He) were used as tracers of groundwater flow in Everglades National Park, South Florida (USA). Both fresh and brackish groundwaters were collected from 47 wells completed at depths ranging from 2 m to 73 m within the Surficial Aquifer System (SAS). Ages as determined by 3H/3He techniques indicate that groundwater within the upper 28 m originated after the nuclear era (within the last 42 yr) and below 28 m before then with evidence of some mixing at the interface. Inter-annual variation of the 3H/3He ages within the upper 28 m was significant throughout the three year investigation, suggesting varying hydrologic conditions. The age of the shallow groundwater in the southern regions of ENP (Rocky Glades and Taylor Slough) tended to be younger following times of high water level when the dominant direction of groundwater flow water was to the southeast. In the same region, significantly older groundwater was observed following times of low water levels and a shift in the groundwater flow direction toward the southwest. Near the canals, the reverse occurred with the ages of shallow groundwater tending to be younger following times of low water levels, suggesting a greater influence of recharge water from the canals to the surrounding aquifer. Although water levels and the direction of hydrologic gradients vary greatly within a 3-month time period, the average age of the shallow (Aquifer suggesting a preferential flow path to the deeper formation. An increase in 4He with depth suggests that radiogenic 4He produced in the underlying Hawthorn Group is dispersed into the SAS. Higher Δ 4He values in brackish groundwaters compared to fresh waters from similar depths indicate an enhanced vertical transport of 4He in the seawater mixing zone. Seawater intrudes at distances of 6 to 28 km at shallow depths (Florida Bay and the Gulf of Mexico over an approximately 6 to 28 km wide strip that parallels the coastline.

Ground-water flow in the surficial aquifer system and potential movement of contaminants from selected waste-disposal sites at Cecil Field Naval Air Station, Jacksonville, Florida

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Halford, K.J.

1998-01-01

As part of the Installation Restoration Program, Cecil Field Naval Air Station, Jacksonville, Florida, is considering remedialaction alternatives to control the possible movement of contaminants from sites that may discharge to the surface. This requires a quantifiable understanding of ground-water flow through the surficial aquifer system and how the system will respond to any future stresses. The geologic units of interest in the study area consist of sediments of Holocene to Miocene age that extend from land surface to the base of the Hawthorn Group. The hydrogeology within the study area was determined from gamma-ray and geologists? logs. Ground-water flow through the surficial aquifer system was simulated with a seven-layer, finite-difference model that extended vertically from the water table to the top of the Upper Floridan aquifer. Results from the calibrated model were based on a long-term recharge rate of 6 inches per year, which fell in the range of 4 to 10 inches per year, estimated using stream hydrograph separation methods. More than 80 percent of ground-water flow circulates within the surficial-sand aquifer, which indicates that most contaminant movement also can be expected to move through the surficial-sand aquifer alone. The surficial-sand aquifer is the uppermost unit of the surficial aquifer system. Particle-tracking results showed that the distances of most flow paths were 1,500 feet or less from a given site to its discharge point. For an assumed effective porosity of 20 percent, typical traveltimes are 40 years or less. At all of the sites investigated, particles released 10 feet below the water table had shorter traveltimes than those released 40 feet below the water table. Traveltimes from contaminated sites to their point of discharge ranged from 2 to 300 years. The contributing areas of the domestic supply wells are not very extensive. The shortest traveltimes for particles to reach the domestic supply wells from their respective

Mining districts in the Carson Sink region, Nevada

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Schrader, F.

1947-01-01

The region lies in an area of primarily sedimentary rocks which are principally Mesozoic and are tilted, folded, and faulted and cut by granular intrusives, and flooded by Tertiary lavas as shown on Figure 4. The Mesozoic sediments were strongly folded and invaded by granular intrusives at or about the time of the intrusion of the great Sierra Nevada batholith. The rocks are exposed chiefly in the mountain ranges and hills.The mountain ranges are mostly fault ranges with much of their structure monoclinical. Faulting in many instances has been prominent since the deposition of the Tertiary lavas and continues down to the present, as shown by fresh scarps and recent earthquake disturbances in the Stillwater and Augusta ranges and in general along the flaks of the various ranges by the tilted attitude of the lava flows and lake beds, and by the older lavas in general being tilted at steeper angles than the overlying lake beds. The faulting may be normal or overthrust.The faulting shown in the various mining districts as Fairview and Wonder may be regarded as indicating that of the region in general.In some parts of the region faulting is so young that it is still shown in the topographic forms as by trunctated gulches in the east base of the Stillwater range in Dixie Valley.As the writer in the present work had but small opportunity to examine the rocks excepting in the various mining districts many of which are located far apart, the accompanying geologic map (Fig. 4) is largely compiled from earlier reports of various authors in order to here present a geologic picture of the region. The portion to the north of Latitude 39°30’ is largely adapted from the 40th Parallel Survey and that to the south of the 39th parallel form the papers and reports by Buwalda, Clark, Merriam, Hill, Spurr, and the unpublished work of H. G. Ferguson of the U. S. Geological Survey on the Hawthorne and Tonopah quadrangles.

The anatomy of clinical decision-making in multidisciplinary cancer meetings

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Soukup, Tayana; Petrides, Konstantinos V.; Lamb, Benjamin W.; Sarkar, Somita; Arora, Sonal; Shah, Sujay; Darzi, Ara; Green, James S. A.; Sevdalis, Nick

2016-01-01

Abstract In the UK, treatment recommendations for patients with cancer are routinely made by multidisciplinary teams in weekly meetings. However, their performance is variable. The aim of this study was to explore the underlying structure of multidisciplinary decision-making process, and examine how it relates to team ability to reach a decision. This is a cross-sectional observational study consisting of 1045 patient reviews across 4 multidisciplinary cancer teams from teaching and community hospitals in London, UK, from 2010 to 2014. Meetings were chaired by surgeons. We used a validated observational instrument (Metric for the Observation of Decision-making in Cancer Multidisciplinary Meetings) consisting of 13 items to assess the decision-making process of each patient discussion. Rated on a 5-point scale, the items measured quality of presented patient information, and contributions to review by individual disciplines. A dichotomous outcome (yes/no) measured team ability to reach a decision. Ratings were submitted to Exploratory Factor Analysis and regression analysis. The exploratory factor analysis produced 4 factors, labeled “Holistic and Clinical inputs” (patient views, psychosocial aspects, patient history, comorbidities, oncologists’, nurses’, and surgeons’ inputs), “Radiology” (radiology results, radiologists’ inputs), “Pathology” (pathology results, pathologists’ inputs), and “Meeting Management” (meeting chairs’ and coordinators’ inputs). A negative cross-loading was observed from surgeons’ input on the fourth factor with a follow-up analysis showing negative correlation (r = −0.19, P < 0.001). In logistic regression, all 4 factors predicted team ability to reach a decision (P < 0.001). Hawthorne effect is the main limitation of the study. The decision-making process in cancer meetings is driven by 4 underlying factors representing the complete patient profile and contributions to case review by all core

SU-E-T-408: Evaluation of the Type and Frequency of Variations Discovered During Routine Secondary Patient Chart Review

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Hardin, M; Harrison, A; Lockamy, V; Li, J; Peng, C; Potrebko, P; Yu, Y; Doyle, L; Cao, J

2015-01-01

Purpose: Desire to improve efficiency and throughput inspired a review of our physics chart check procedures. Departmental policy mandates plan checks pre-treatment, after first treatment and weekly every 3–5 days. This study examined the effectiveness of the “after first” check with respect to improving patient safety and clinical efficiency. Type and frequency of variations discovered during this redundant secondary review was examined over seven months. Methods: A community spreadsheet was created to record variations in care discovered during chart review following the first fraction of treatment and before the second fraction (each plan reviewed prior to treatment). Entries were recorded from August 2014 through February 2015, amounting to 43 recorded variations out of 906 reviewed charts. The variations were divided into categories and frequencies were assessed month-to-month. Results: Analysis of recorded variations indicates an overall variation rate of 4.7%. The initial rate was 13.5%; months 2–7 average 3.7%. The majority of variations related to discrepancies in documentation at 46.5%, followed by prescription, plan deficiency, and dose tracking related variations at 25.5%, 12.8%, and 12.8%, respectively. Minor variations (negligible consequence on patient treatment) outweighed major variations 3 to 1. Conclusion: This work indicates that this redundant secondary check is effective. The first month spike in rates could be due to the Hawthorne/observer effect, but the consistent 4% variation rate suggests the need for periodical re-training on variations noted as frequent to improve awareness and quality of the initial chart review process, which may lead to improved treatment quality, patient safety and increased clinical efficiency. Utilizing these results, a continuous quality improvement process following Deming’s Plan-Do-Study-Act (PDSA) methodology was generated. The first iteration of this PDSA was adding a specific dose tracking

SU-E-T-408: Evaluation of the Type and Frequency of Variations Discovered During Routine Secondary Patient Chart Review

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Hardin, M; Harrison, A; Lockamy, V; Li, J; Peng, C; Potrebko, P; Yu, Y; Doyle, L; Cao, J [Thomas Jefferson University, Philadelphia, PA (United States)

2015-06-15

Purpose: Desire to improve efficiency and throughput inspired a review of our physics chart check procedures. Departmental policy mandates plan checks pre-treatment, after first treatment and weekly every 3–5 days. This study examined the effectiveness of the “after first” check with respect to improving patient safety and clinical efficiency. Type and frequency of variations discovered during this redundant secondary review was examined over seven months. Methods: A community spreadsheet was created to record variations in care discovered during chart review following the first fraction of treatment and before the second fraction (each plan reviewed prior to treatment). Entries were recorded from August 2014 through February 2015, amounting to 43 recorded variations out of 906 reviewed charts. The variations were divided into categories and frequencies were assessed month-to-month. Results: Analysis of recorded variations indicates an overall variation rate of 4.7%. The initial rate was 13.5%; months 2–7 average 3.7%. The majority of variations related to discrepancies in documentation at 46.5%, followed by prescription, plan deficiency, and dose tracking related variations at 25.5%, 12.8%, and 12.8%, respectively. Minor variations (negligible consequence on patient treatment) outweighed major variations 3 to 1. Conclusion: This work indicates that this redundant secondary check is effective. The first month spike in rates could be due to the Hawthorne/observer effect, but the consistent 4% variation rate suggests the need for periodical re-training on variations noted as frequent to improve awareness and quality of the initial chart review process, which may lead to improved treatment quality, patient safety and increased clinical efficiency. Utilizing these results, a continuous quality improvement process following Deming’s Plan-Do-Study-Act (PDSA) methodology was generated. The first iteration of this PDSA was adding a specific dose tracking

Prevention of dimethylsulfoxide-related nausea and vomiting by prophylactic administration of ondansetron for patients receiving autologous cryopreserved peripheral blood stem cells.

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Eisenberg, Seth; Wickline, Mihkaila; Linenberger, Michael; Gooley, Ted; Holmberg, Leona

2013-05-01

To evaluate the effectiveness of ondansetron for the prevention of nausea and vomiting from dimethylsulfoxide (DMSO) during autologous stem cell transplantation (ASCT) infusion. Nonrandomized cohort using historical control. Comprehensive cancer center outpatient infusion department. 50 patients receiving ASCT in the outpatient setting. Patients were assessed for nausea and vomiting on their infusion day using the Multinational Association of Supportive Care in Cancer Antiemesis Tool (MAT) at arrival, pre-ASCT infusion, pre-ondansetron administration, prior to the first bag, and after each bag of stem cells. A standard script was used to ensure consistency. Ondansetron, 16 mg IV, was administered 30-90 minutes prior to each ASCT infusion. Number and volume of stem cells bags, as well as infusion rate and emesis episodes, were recorded. Nausea scores and vomiting episodes were compared to historical data. Subjectivity of nausea, potential Hawthorne Effect. Forty-five percent of patients had an MAT score greater than 2 on arrival, decreasing to 18% after receiving ondansetron before the first bag. Twenty-four percent had MAT increases of more than two points by infusion end compared to 58% in the historic control group. Eighteen percent of patients vomited compared to 28% of historic controls. The administration of 16 mg of IV ondansetron significantly reduced DMSO-related nausea and episodes of vomiting in patients receiving ASCT. Prophylactic administration of ondansetron had a positive effect on reducing nausea symptoms and episodes of vomiting during ASCT infusions. These results prompted a change in clinical practice. More research is required to determine whether the inclusion of other antiemetic agents would provide even greater benefit. To date, no other published studies have explored the benefits of premedicating patients with ondansetron prior to ASCT infusions. This study is the first to establish efficacy of ondansetron for an unlabeled indication. These

The effect of different cardiovascular risk presentation formats on intentions, understanding and emotional affect: a randomised controlled trial using a web-based risk formatter (protocol

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Newcombe Robert

2010-07-01

Full Text Available Abstract Background The future risk of heart disease can be predicted with increasing precision. However, more research is needed into how this risk is conveyed and presented. The aim of this study is to compare the effects of presenting cardiovascular risk in different formats on individuals' intention to change behaviour to reduce risk, understanding of risk information and emotional affect. Methods/design A randomised controlled trial comprising four arms, with a between subjects design will be performed. There will be two intervention groups and two control groups. The first control comprises a pre-intervention questionnaire and presents risk in a bar graph format. The second control presents risk in a bar graph format without pre-intervention questionnaire. These two control groups are to account for the potential Hawthorne effect of thinking about cardiovascular risk before viewing actual risk. The two intervention groups comprise presenting risk in either a pictogram or metonym format (image depicting seriousness of having a myocardial infarction. 800 individuals' aged between 45 and 64 years, who have not been previously diagnosed with heart disease and have access to a computer with internet, will be given a link to a website comprising a risk calculator and electronic questionnaires. 10-year risk of having a coronary heart disease event will be assessed and presented in one of the three formats. A post-intervention questionnaire will be completed after viewing the risk format. Main outcome measures are (i intention to change behaviour, (ii understanding of risk information, (iii emotional affect and (iv worry about future heart disease. Secondary outcomes are the sub-components of the theory of planned behaviour: attitudes, perceived behavioural control and subjective norms. Discussion Having reviewed the literature, we are not aware of any other studies which have used the assessment of actual risk, in a trial to compare different

Geomorphology, facies architecture, and high-resolution, non-marine sequence stratigraphy in avulsion deposits, Cumberland Marshes, Saskatchewan

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Farrell, K. M.

2001-02-01

This paper demonstrates field relationships between landforms, facies, and high-resolution sequences in avulsion deposits. It defines the building blocks of a prograding avulsion sequence from a high-resolution sequence stratigraphy perspective, proposes concepts in non-marine sequence stratigraphy and flood basin evolution, and defines the continental equivalent to a parasequence. The geomorphic features investigated include a distributary channel and its levee, the Stage I crevasse splay of Smith et al. (Sedimentology, vol. 36 (1989) 1), and the local backswamp. Levees and splays have been poorly studied in the past, and three-dimensional (3D) studies are rare. In this study, stratigraphy is defined from the finest scale upward and facies are mapped in 3D. Genetically related successions are identified by defining a hierarchy of bounding surfaces. The genesis, architecture, geometry, and connectivity of facies are explored in 3D. The approach used here reveals that avulsion deposits are comparable in process, landform, facies, bounding surfaces, and scale to interdistributary bayfill, i.e. delta lobe deposits. Even a simple Stage I splay is a complex landform, composed of several geomorphic components, several facies and many depositional events. As in bayfill, an alluvial ridge forms as the feeder crevasse and its levees advance basinward through their own distributary mouth bar deposits to form a Stage I splay. This produces a shoestring-shaped concentration of disconnected sandbodies that is flanked by wings of heterolithic strata, that join beneath the terminal mouth bar. The proposed results challenge current paradigms. Defining a crevasse splay as a discrete sandbody potentially ignores 70% of the landform's volume. An individual sandbody is likely only a small part of a crevasse splay complex. The thickest sandbody is a terminal, channel associated feature, not a sheet that thins in the direction of propagation. The three stage model of splay evolution

Additive effects of nutritional supplementation, together with bisphosphonates, on bone mineral density after hip fracture: a 12-month randomized controlled study

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Flodin L

2014-07-01

Full Text Available Lena Flodin,1,2 Maria Sääf,3 Tommy Cederholm,4 Amer N Al-Ani,2,5 Paul W Ackermann,5,6 Eva Samnegård,7 Nils Dalen,7 Margareta Hedström2,51Department of Geriatric Medicine, Karolinska University Hospital Stockholm, Sweden; 2Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Stockholm, Sweden; 3Department of Endocrinology, Metabolism, and Diabetes, Karolinska University Hospital, Stockholm, Sweden; 4Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden; 5Department of Orthopedics, Karolinska University Hospital, Stockholm, Sweden; 6Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden; 7Department of Clinical Science, Division of Orthopedics, Karolinska Institutet, Danderyd Hospital, Stockholm, SwedenBackground: After a hip fracture, a catabolic state develops, with increased bone loss during the first year. The aim of this study was to evaluate the effects of postoperative treatment with calcium, vitamin D, and bisphosphonates (alone or together with nutritional supplementation on total hip and total body bone mineral density (BMD.Methods: Seventy-nine patients (56 women, with a mean age of 79 years (range, 61–96 years and with a recent hip fracture, who were ambulatory before fracture and without severe cognitive impairment, were included. Patients were randomized to treatment with bisphosphonates (risedronate 35 mg weekly for 12 months (B; n=28, treatment with bisphosphonates along with nutritional supplementation (40 g protein, 600 kcal daily for the first 6 months (BN; n=26, or to controls (C; n=25. All participants received calcium (1,000 mg and vitamin D3 (800 IU daily. Total hip and total body BMD were assessed with dual-energy X-ray absorptiometry at baseline, 6, and 12 months. Marker of bone resorption C-terminal telopeptide of collagen I and 25-hydroxy vitamin D were analyzed in serum

Apathy and depressive symptoms in older people and incident myocardial infarction, stroke, and mortality: a systematic review and meta-analysis of individual participant data

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Eurelings LSM

2018-04-01

Full Text Available Lisa SM Eurelings,1,* Jan Willem van Dalen,1,* Gerben ter Riet,2 Eric P Moll van Charante,2 Edo Richard,1,3 Willem A van Gool1 On behalf of the ICARA Study Group 1Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands; 2Department of General Practice, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands; 3Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Radboud University Medical Centre, Nijmegen, the Netherlands *These authors contributed equally to this work Background: Previous findings suggest that apathy symptoms independently of depressive symptoms measured using the Geriatric Depression Scale (GDS are associated with cardiovascular disease (CVD in older individuals.Aims: To study whether apathy and depressive symptoms in older people are associated with future CVD, stroke, and mortality using individual patient-data meta-analysis.Methods: Medline, Embase, and PsycInfo databases up to September 3, 2013, were systematically searched without language restrictions. We sought prospective studies with older (mean age ≥65 years community-dwelling populations in which the GDS was employed and subsequent stroke and/or CVD were recorded to provide individual participant data. Apathy symptoms were defined as the three apathy-related subitems of the GDS, with depressive symptoms the remaining items. We used myocardial infarction (MI, stroke, and all-cause mortality as main outcomes. Analyses were adjusted for age, sex, and MI/stroke history. An adaptation of the Newcastle–Ottawa scale was used to evaluate bias. Hazard ratios were calculated using one-stage random-effect Cox regression models.Results: Of the 52 eligible studies, 21 (40.4% were included, comprising 47,625 older people (mean age [standard deviation] 74 [7.4] years, over a median follow-up of 8.8 years. Participants with apathy symptoms had a 21% higher risk of MI (95% confidence

The Status of Erwinia amylovora in the Former Yugoslav Republics over the Past Two Decades

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Mila Grahovac

2013-01-01

Full Text Available Erwinia amylovora, the causal agent of fire blight (FB on fruit trees and ornamentalplants, rapidly spread across eastern Mediterranean countries in the early 1980s. This quarantinebacterium probably arrived in the southern parts of the former Yugoslavia (nowFYR Macedonia from Greece. Based on symptoms, and isolation and identification data, itwas concluded that Erwinia amylovora was the causal agent of pear drying in Macedonia(1989. It was the first experimental confirmation of a presence of E. amylovora in the territoryof the former Yugoslavia. The presence of E. amylovora was also proved in Serbia thatsame year. In Bosnia and Herzegovina, FB was detected during 1990. Based on an officialreport filed with the Federal Ministry of Agriculture in Belgrade, the presence of E. amylovorain Yugoslavia was confirmed (EPPO – Reporting Service, 1991. Therefore, the presenceof the bacterium E. amylovora in the territory of Yugoslavia was officially confirmedin 1990. In Croatia, FB was first observed in villages near the border on Serbia in 1995.In Montenegro, FB was first detected in 1996. In Slovenia, FB appeared as late as in 2001.E. amylovora is now present on 10 hosts (pear, wild pear, apple, quince, medlar, mountainash,hawthorn, firethorn, cotoneaster and Japanese quince in the territory ofthe former Yugoslav republics. Based on literature data, losses caused by FB in theformer Yugoslav republics in the period 1989-1992 were estimated at about12,000,000 DEM (mostly in Macedonia and in the period 1992–1996 at 6,000,000 DEM.Total damage in a more recent epiphytotic year in Slovenia (2003 was estimated atabout 474,200 EUR.Conventional and up-to-date rapid methods (PCR, ELISA and IF, BIOLOG and API System,FAME and SDS-PAGE have been used to identify E. amylovora. Mainly preventive measures have been used to control E. amylovora in the former Yugoslav republics. Spraying withcopper products has been practiced during the dormant period and in early

Study protocol for a randomized controlled trial of telephone-delivered cognitive behavior therapy compared with befriending for treating depression and anxiety in older adults with COPD

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Doyle C

2016-02-01

Full Text Available Colleen Doyle,1 David Dunt,2 David Ames,3 Marcia Fearn,3 Emily (Chuanmei You,1 Sunil Bhar41Australian Catholic University, Melbourne, VIC, Australia; 2Centre for Health Policy, The University of Melbourne, Melbourne, VIC, Australia; 3National Ageing Research Institute, Melbourne, VIC, Australia; 4Department of Psychological Sciences, Swinburne University of Technology, Hawthorn, VIC, AustraliaBackground: COPD is an umbrella term to describe chronic lung diseases that cause limitations in lung airflow, including emphysema and chronic bronchitis. The prevalence of depression and anxiety in people with COPD is high, although these comorbidities are often undiagnosed, untreated, or undertreated. There is a need to identify efficacious treatments for depression and anxiety in people with COPD. Cognitive behavior therapy (CBT for the treatment of anxiety and depression has a strong evidence base. There has been some success delivering this treatment over the telephone in limited studies. The aim of this study is to evaluate the efficacy of both telephone-administered CBT and befriending on outcomes for patients with diagnosed COPD who have at least mild levels of depression and/or anxiety.Methods: The protocol described in this paper is of a pragmatic randomized controlled trial comparing eight sessions of telephone CBT to an active social control, referred to as befriending. Primary outcome measures will include depression and anxiety symptoms, and secondary outcome measures will include quality of life, self-efficacy, and COPD symptom severity. Participants’ satisfaction with the intervention and therapeutic alliance will also be assessed. Measures will be taken pre- and postdelivery of the intervention and again at 8 weeks following the intervention.Conclusion: People with COPD often have limitations to their mobility because of their breathlessness. They are often already attending many medical appointments and could be reluctant to attend for

Diversity of plant defense elicitor peptides within the Rosaceae.

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Ruiz, Cristina; Nadal, Anna; Foix, Laura; Montesinos, Laura; Montesinos, Emilio; Pla, Maria

2018-01-23

Plant elicitor peptides (Peps) are endogenous molecules that induce and amplify the first line of inducible plant defense, known as pattern-triggered immunity, contributing to protect plants against attack by bacteria, fungi and herbivores. Pep topic application and transgenic expression have been found to enhance disease resistance in a small number of model plant-pathogen systems. The action of Peps relies on perception by specific receptors, so displaying a family-specific activity. Recently, the presence and activity of Peps within the Rosaceae has been demonstrated. Here we characterized the population of Pep sequences within the economically important plant family of Rosaceae, with special emphasis on the Amygdaleae and Pyreae tribes, which include the most relevant edible species such as apple, pear and peach, and numerous ornamental and wild species (e.g. photinia, firethorn and hawthorn). The systematic experimental search for Pep and the corresponding precursor PROPEP sequences within 36 Amygdaleae and Pyreae species, and 100 cultivars had a highly homogeneous pattern, with two tribe-specific Pep types per plant, i.e. Pep1 and Pep2 (Amygdaleae) or Pep3 and Pep4 (Pyreae). Pep2 and Pep3 are highly conserved, reaching identity percentages similar to those of genes used in plant phylogenetic analyses, while Pep1 and Pep4 are somewhat more variable, with similar values to the corresponding PROPEPs. In contrast to Pep3 and Pep4, Pep1 and Pep2 sequences of different species paralleled their phylogenetic relationships, and putative ancestor sequences were identified. The large amount of sequences allowed refining of a C-terminal consensus sequence that would support the protective activity of Pep1-4 in a Prunus spp. and Xanthomonas arboricola pv. pruni system. Moreover, tribe-specific consensus sequences were deduced at the center and C-terminal regions of Peps, which might explain the higher protection efficiencies described upon topic treatments with Peps from

Action to Support Practices Implement Research Evidence (ASPIRE): protocol for a cluster-randomised evaluation of adaptable implementation packages targeting 'high impact' clinical practice recommendations in general practice.

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Willis, Thomas A; Hartley, Suzanne; Glidewell, Liz; Farrin, Amanda J; Lawton, Rebecca; McEachan, Rosemary R C; Ingleson, Emma; Heudtlass, Peter; Collinson, Michelle; Clamp, Susan; Hunter, Cheryl; Ward, Vicky; Hulme, Claire; Meads, David; Bregantini, Daniele; Carder, Paul; Foy, Robbie

2016-02-29

There are recognised gaps between evidence and practice in general practice, a setting which provides particular challenges for implementation. We earlier screened clinical guideline recommendations to derive a set of 'high impact' indicators based upon criteria including potential for significant patient benefit, scope for improved practice and amenability to measurement using routinely collected data. We aim to evaluate the effectiveness and cost-effectiveness of a multifaceted, adaptable intervention package to implement four targeted, high impact recommendations in general practice. The research programme Action to Support Practice Implement Research Evidence (ASPIRE) includes a pair of pragmatic cluster-randomised trials which use a balanced incomplete block design. Clusters are general practices in West Yorkshire, United Kingdom (UK), recruited using an 'opt-out' recruitment process. The intervention package adapted to each recommendation includes combinations of audit and feedback, educational outreach visits and computerised prompts with embedded behaviour change techniques selected on the basis of identified needs and barriers to change. In trial 1, practices are randomised to adapted interventions targeting either diabetes control or risky prescribing and those in trial 2 to adapted interventions targeting either blood pressure control in patients at risk of cardiovascular events or anticoagulation in atrial fibrillation. The respective primary endpoints comprise achievement of all recommended target levels of haemoglobin A1c (HbA1c), blood pressure and cholesterol in patients with type 2 diabetes, a composite indicator of risky prescribing, achievement of recommended blood pressure targets for specific patient groups and anticoagulation prescribing in patients with atrial fibrillation. We are also randomising practices to a fifth, non-intervention control group to further assess Hawthorne effects. Outcomes will be assessed using routinely collected data

Measuring stock and change in the GB countryside for policy--key findings and developments from the Countryside Survey 2007 field survey.

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Norton, L R; Maskell, L C; Smart, S S; Dunbar, M J; Emmett, B A; Carey, P D; Williams, P; Crowe, A; Chandler, K; Scott, W A; Wood, C M

2012-12-30

Countryside Survey is a unique large scale long-term monitoring programme investigating stock and change of habitats, landscape features, vegetation, soil and freshwaters of Great Britain. Repeat field surveys combine policy and scientific objectives to provide evidence on how multiple aspects of the environment are changing over time, a key goal of international science in the face of profound human impacts on ecosystems. Countryside Survey 2007 (CS2007), the fifth survey since 1978, retained consistency with previous surveys, whilst evolving in line with technological and conceptual advances in the collection and integration of data to understand landscape change. This paper outlines approaches taken in the 2007 survey and its subsequent analysis and presents some of the headline results of the survey and their relevance for national and international policy objectives. Key changes between 1998 and 2007 included: a) significant shifts in agricultural land cover from arable to grassland, accompanied by increases in the area of broadleaved woodland, b) decreases in the length of managed hedges associated with agricultural land, as a proportion deteriorated to lines of trees and c) increases in the areas and numbers of wet habitats (standing open water, ponds) and species preferring wetter conditions (1998-2007 and 1978-2007). Despite international policy directed at maintaining and enhancing biodiversity, there were widespread decreases in species richness in all linear and area habitats, except on arable land, consistent with an increase in competitive and late successional species between 1998 and 2007 and 1978 and 2007. Late successional and competitive species: Stinging nettle (Urtica dioica), Hawthorn (Cratageous monogyna) and Bramble (Rubus fruticosus), in the top ten recorded species recorded in 2007, all increased between 1998 and 2007. The most commonly recorded species in CS (1990, 1998 and 2007) was agricultural Ryegrass (Lolium perenne). Increases in

Constraining friction, dilatancy and effective stress with earthquake rates in the deep crust

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Beeler, N. M.; Thomas, A.; Burgmann, R.; Shelly, D. R.

2015-12-01

Similar to their behavior on the deep extent of some subduction zones, families of recurring low-frequency earthquakes (LFE) within zones of non-volcanic tremor on the San Andreas fault in central California show strong sensitivity to stresses induced by the tides. Taking all of the LFE families collectively, LFEs occur at all levels of the daily tidal stress, and are in phase with the very small, ~200 Pa, shear stress amplitudes while being uncorrelated with the ~2 kPa tidal normal stresses. Following previous work we assume LFE sources are small, persistent regions that repeatedly fail during shear within a much larger scale, otherwise aseismically creeping fault zone and that the correlation of LFE occurrence reflects modulation of the fault creep rate by the tidal stresses. We examine the predictions of laboratory-observed rate-dependent dilatancy associated with frictional slip. The effect of dilatancy hardening is to damp the slip rate, so high dilatancy under undrained pore pressure reduces modulation of slip rate by the tides. The undrained end-member model produces: 1) no sensitivity to the tidal normal stress, as first suggested in this context by Hawthorne and Rubin [2010], and 2) fault creep rate in phase with the tidal shear stress. Room temperature laboratory-observed values of the dilatancy and friction coefficients for talc, an extremely weak and weakly dilatant material, under-predict the observed San Andreas modulation at least by an order of magnitude owing to too much dilatancy. This may reflect a temperature dependence of the dilatancy and friction coefficients, both of which are expected to be zero at the brittle-ductile transition. The observed tidal modulation constrains the product of the friction and dilatancy coefficients to be at most 5 x 10-7 in the LFE source region, an order of magnitude smaller than observed at room temperature for talc. Alternatively, considering the predictions of a purely rate-dependent talc friction would

Determination of premining geochemical background and delineation of extent of sediment contamination in Blue Creek downstream from Midnite Mine, Stevens County, Washington

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Church, Stan E.; Kirschner, Frederick E.; Choate, LaDonna M.; Lamothe, Paul J.; Budahn, James R.; Brown, Zoe Ann

2008-01-01

geochemical background determined upstream of the mine site. Postmining metal concentrations in sediment are lower than during the mining period, but remain elevated relative to premining geochemical background. Furthermore, the sediment composition of surface sediment in the Blue Creek delta is contaminated. Base-metal contamination by arsenic, cadmium, lead, and zinc in sediment in the delta in Blue Creek cove is dominated by suspended sediment from the Coeur d?Alene mining district. Uranium contamination in surface sediment in the delta of Blue Creek cove extends at least 500 meters downstream from the mouth of Blue Creek as defined by the 1,290-ft elevation boundary between lands administered by the National Park Service and the Spokane Indian Tribe. Comparisons of the premining geochemical background to sediment sampled during the period the mine was in operation, and to the sediment data from the postmining period, are used to delineate the extent of contaminated sediment in Blue Creek cove along the thalweg of Blue Creek into Lake Roosevelt. The extent of contamination out into Lake Roosevelt by mining remains open.

Bias, Confounding, and Interaction: Lions and Tigers, and Bears, Oh My!

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Vetter, Thomas R; Mascha, Edward J

2017-09-01

Epidemiologists seek to make a valid inference about the causal effect between an exposure and a disease in a specific population, using representative sample data from a specific population. Clinical researchers likewise seek to make a valid inference about the association between an intervention and outcome(s) in a specific population, based upon their randomly collected, representative sample data. Both do so by using the available data about the sample variable to make a valid estimate about its corresponding or underlying, but unknown population parameter. Random error in an experiment can be due to the natural, periodic fluctuation or variation in the accuracy or precision of virtually any data sampling technique or health measurement tool or scale. In a clinical research study, random error can be due to not only innate human variability but also purely chance. Systematic error in an experiment arises from an innate flaw in the data sampling technique or measurement instrument. In the clinical research setting, systematic error is more commonly referred to as systematic bias. The most commonly encountered types of bias in anesthesia, perioperative, critical care, and pain medicine research include recall bias, observational bias (Hawthorne effect), attrition bias, misclassification or informational bias, and selection bias. A confounding variable is a factor associated with both the exposure of interest and the outcome of interest. A confounding variable (confounding factor or confounder) is a variable that correlates (positively or negatively) with both the exposure and outcome. Confounding is typically not an issue in a randomized trial because the randomized groups are sufficiently balanced on all potential confounding variables, both observed and nonobserved. However, confounding can be a major problem with any observational (nonrandomized) study. Ignoring confounding in an observational study will often result in a "distorted" or incorrect estimate of

Numerical study of the effect of earth tides on recurring short-term slow slip events

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Matsuzawa, T.; Tanaka, Y.; Shibazaki, B.

2017-12-01

Short-term slow slip events (SSEs) in the Nankai region are affected by earth tides (e.g., Nakata et al., 2008; Ide and Tanaka, 2014; Yabe et al., 2015). The effect of tidal stress on the SSEs is also examined numerically (e.g., Hawthorne and Rubin, 2013). In our previous study (Matsuzawa et al., 2017, JpGU-AGU), we numerically simulated SSEs in the Shikoku region, and reported that tidal stress makes the variance of recurrence intervals of SSEs smaller in relatively isolated SSE regions. However, the reason of such stable recurrence was not clear. In this study, we examine the tidal effect on short-term SSEs based on a flat plate and a realistic plate model (e.g., Matsuzawa et al., 2013, GRL). We adopt a rate- and state-dependent friction law (RS-law) with cutoff velocities as in our previous studies (Matsuzawa et al., 2013). We assume that (a-b) value in the RS-law is negative within the short-term SSE region, and positive outside the region. In a flat plate model, the short-term SSE region is a circular patch with the radius of 6 km. In a realistic plate model, the short-term SSE region is based on the actual distribution of low-frequency tremor. Low effective normal stress is assumed at the depth of SSEs. Calculating stress change by earth tides as in Yabe et al., (2015), we examine the stress perturbation by two different earth tides with the period of semidiurnal (M2) and fortnight (Mf) tide in this study. In the result of a flat plate case, amplitude of SSEs becomes smaller just after the slip at whole simulated area. Recurring SSEs become clear again within one year in the case with tides (M2 or Mf), while the recurrence becomes clear after seven years in the case without tides. Interestingly, the effect of the Mf tide is similar to the case with the M2 tide, even though the amplitude of the Mf tide (0.01 kPa) is two-order smaller than that of the M2 tide. In the realistic plate model of Shikoku, clear recurrence of short-term SSEs is found earlier than the

How to Break a Taboo? Comment briser un tabou ? ¿Cómo romper un tabú?

Directory of Open Access Journals (Sweden)

Jack Sim

2011-12-01

Full Text Available Prior to 2001, the word toilet and sanitation was a taboo. Polite society avoided the embarrassment of mentioning it. Academia publications about the issues were viewed as too boring to engage mass media. But avoidance of this agenda manifested into neglect of 2.6 billion people without access to proper sanitation and the death of 1.5 million children through diarrhea annually. Jack Sim broke this taboo through the creation of the World Toilet Organization (WTO. With its unique blend of humor and facts, WTO called a spade a spade and took the global media by storm advocating for better toilets, sanitation and hygiene conditions for people all over the world. This article explains how he did it with a shoe-string budget and went on to mobilize everyone to change the world of sanitation and toilets.Avant 2001, les mots « toilettes » et « assainissement » étaient tabous. Il n’était pas de bon ton de les prononcer. Les publications universitaires sur le sujet étaient considérées comme trop ennuyeuses pour pouvoir susciter l'intérêt des médias grand public. Cependant, le fait de se désintéresser du sujet revenait à laisser à l’écart 2,6 milliards de personnes qui n’avaient pas accès à des systèmes d’assainissement corrects et à ignorer le décès de 1,5 million d’enfants dû à une diarrhée chaque année. Jack Sim a brisé ce tabou en créant la World Toilet Organization (WTO. Avec son mélange unique d’humour et de données factuelles, la WTO a appelé un chat un chat et a investi les médias internationaux afin de sensibiliser le maximum de personnes à la nécessité de mettre en place des systèmes de toilettes et d’assainissement plus efficaces et de meilleures conditions d’hygiène dans le monde entier. Cet article explique comment Jack Sim a réussi, avec un budget très limité, à inciter chacun à faire évoluer l’univers des systèmes d’assainissement et de toilettes.Antes de 2001, los términos �

The chemistry of hydrothermal magnetite: a review

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Nadoll, Patrick; Angerer, Thomas; Mauk, Jeffrey L.; French, David; Walshe, John

2014-01-01

Magnetite (Fe3O4) is a well-recognized petrogenetic indicator and is a common accessory mineral in many ore deposits and their host rocks. Recent years have seen an increased interest in the use of hydrothermal magnetite for provenance studies and as a pathfinder for mineral exploration. A number of studies have investigated how specific formation conditions are reflected in the composition of the respective magnetite. Two fundamental questions underlie these efforts — (i) How can the composition of igneous and, more importantly, hydrothermal magnetite be used to discriminate mineralized areas from barren host rocks, and (ii) how can this assist exploration geologists to target ore deposits at greater and greater distances from the main mineralization? Similar to igneous magnetite, the most important factors that govern compositional variations in hydrothermal magnetite are (A) temperature, (B) fluid composition — element availability, (C) oxygen and sulfur fugacity, (D) silicate and sulfide activity, (E) host rock buffering, (F) re-equilibration processes, and (G) intrinsic crystallographic controls such as ionic radius and charge balance. We discuss how specific formation conditions are reflected in the composition of magnetite and review studies that investigate the chemistry of hydrothermal and igneous magnetite from various mineral deposits and their host rocks. Furthermore, we discuss the redox-related alteration of magnetite (martitization and mushketovitization) and mineral inclusions in magnetite and their effect on chemical analyses. Our database includes published and previously unpublished magnetite minor and trace element data for magnetite from (1) banded iron formations (BIF) and related high-grade iron ore deposits in Western Australia, India, and Brazil, (2) Ag–Pb–Zn veins of the Coeur d'Alene district, United States, (3) porphyry Cu–(Au)–(Mo) deposits and associated (4) calcic and magnesian skarn deposits in the southwestern United

The spectacular rise of holiday kilometers and environmental impacts. Trend analysis of the holiday behaviour of the Dutch in the period 1969-2040; Vakantiekilometers en hun milieu-effecten zullen spectaculair blijven stijgen. Trendanalyse van het Nederlandse vakantiegedrag van 1969 tot 2040

Energy Technology Data Exchange (ETDEWEB)

Mulder, S.; Schalekamp, A.; Sikkel, D.; Zengerink, E.; Van der Horst, T.; Van Velzen, J. [TNS NIPO, Amsterdam (Netherlands); Aalbers, T.; Vringer, K. [Milieu- en Natuur Planbureau MNP, Rijksinstituut voor Volksgezondheid en Milieu RIVM, Bilthoven (Netherlands)

2007-02-15

Natuurplanbureau. De resultaten worden door het MNP gebruikt voor een duurzaamheidsverkenning waarin de toekomstige ontwikkelingen centraal staan.Volgens de trendlijnen zal deze groei nog spectaculair doorzetten naar 40 miljoen vakanties met maar liefst 160 miljard reiskilometers in 2040. Nederlanders gaan dan ruim drie maal per jaar op vakantie en gaan vooral meer vliegen. Van 1.300 km per persoon nu naar 6.000 km in 2040. Mogelijk kunnen de in het regeerakkoord voorgestelde heffingen deze groei afremmen. Het vakantieverkeer per vliegtuig is nu al verantwoordelijk voor 2,5 procent van onze totale uitstoot aan CO2. Dit is ruim twee maal zoveel als het aandeel van het autoverkeer ten behoeve van de vakantie. De CO2-uitstoot van vliegtuigen ligt rond de 200 gram-equivalenten per reizigerskilometer (voor personenauto's is dat ongeveer 125 gram per reizigerskilometer). In de toekomst zal dit mogelijk door gebruik van grotere en zuiniger vliegtuigen met 30 tot 40 procent kunnen dalen, maar dat is lang niet voldoende om de volumegroei te kunnen compenseren. De CO2-uitstoot zal bij ongewijzigd beleid en zonder heffingen naar verwachting verdrievoudigen.

A field test of a web-based workplace health promotion program to improve dietary practices, reduce stress, and increase physical activity: randomized controlled trial.

Science.gov (United States)

Cook, Royer F; Billings, Douglas W; Hersch, Rebekah K; Back, Anita S; Hendrickson, April

2007-06-19

activity, although t tests of pretest-posttest changes indicated that both groups improved on several of these measures. The Web-based group gave significantly higher ratings to the program materials than the print group on all health topics and in their overall evaluation (F(1,410) = 9.808, P = .002). The Web-based program was more effective than print materials in producing improvements in the areas of diet and nutrition but was not more effective in reducing stress or increasing physical activity. The higher ratings given to the Web-based program suggest that workers preferred it to the print materials. Both groups showed numerous pretest-posttest improvements in all health topics, although such improvements might be attributable in part to a Hawthorne effect. Results suggest that a multimedia Web-based program can be a promising means of delivering health promotion material to the workforce, particularly in the area of diet and nutrition.

The Pragmatics of Insensitive Assessments

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Alexander Almér

2010-12-01

Support Moral Objectivism?’ Manuscript.Björnsson, G. & Finlay, S. 2010. ‘Defending Metaethical Contextualism’. Ethics 121: 7–36.Brogaard, B. 2008. ‘Moral Contextualism and Moral Relativism’. The Philosophical Quarterly 58: 385–409.http://dx.doi.org/10.1111/j.1467-9213.2007.543.xCappelen, H. & Hawthorne, J. 2009. Relativism and Monadic Truth. Oxford U. P.http://dx.doi.org/10.1093/acprof:oso/9780199560554.001.0001DeRose, K. 1991. ‘Epistemic Possibilities’. Philosophical Review 100: 581–605.http://dx.doi.org/10.2307/2185175DeRose, K. 1998. ‘Simple Might’s, Indicative Possibilities, and the Open Future’. The Philosophical Quarterly 48: 67–82.http://dx.doi.org/10.1111/1467-9213.00082Dowell, J. 2011. ‘A Flexibly Contextualist Account of Epistemic Modals’. Forthcoming in Philosopher’s Imprint.Egan, A. 2007. ‘Epistemic Modals, Relativism, and Assertion’. Philosophical Studies 133: 1–22.http://dx.doi.org/10.1007/s11098-006-9003-xEgan, A. & Weatherson, B. (eds.. 2011. Epistemic Modality. Oxford U. PEgan, A., Hawthorne, J. & Weatherson, B. 2005. ‘Epistemic Modals in Context’. In ‘Contextualism in Philosophy’, 131–168. Oxford U. P.Finlay, S. ms. ‘Confusion of Tongues: A Theory of Normativity’. Draft of book manuscript.Glanzberg, M. 2007. ‘Context, Content, and Relativism’. Philosophical Studies 136: 1–29.http://dx.doi.org/10.1007/s11098-007-9145-5Kölbel, M. 2004. ‘Faultless Disagreement’. Proceedings of the Aristotelian Society 104: 53–73.Kölbel, M. 2009. ‘The Evidence for Relativism’. Synthese 166: 375–95.Kolodny, N. & MacFarlane, J. ms. ‘Ought: Between Subjective and Objective’. Unpublished manuscript, University of California, Berkeley.Lasersohn, P. 2005. ‘Context Dependence, Disagreement, and Predicates of Personal Taste’. Linguistics and Philosophy 28: 643–686.http://dx.doi.org/10.1007/s10988-005-0596-xMacFarlane, J. 2005. ‘Making Sense of Relative Truth’. Proceedings of the Aristotelian

Dynamics of forest populations in the mountain resort region of the North Caucasus

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Chalaya, Elena; Efimenko, Natalia; Slepykh, Olga; Slepykh, Viktor; Povolotskaya, Nina

2017-04-01

Prehistoric formula of forest species composition of the resort region Caucasian Mineralnye Vody (RR CMV) in the North Caucasus is 6Q3Cb1Fe [1]. According to it, undisturbed forests of the region consisted of the pedunculate oak (Quercus robur L.) and the durmast (Quercus cerris L.) by 60%, the European hornbeam (Carpinus betulus L.) by 30% and the European ash (Fraxinus excelsior L.) only by 10%. At present the formula of forest composition of the region is 5Fe3Cb2Q, according to it, the rate of oak-groves (the most valuable to resort landscape gardening) has reduced to 20%, and the ash-tree, though the rate of the hornbeam has not changed, increased up to 50%. Forest breeding populations in the RR CMV are referred to natural medical resources as they have high rehabilitation and climate-regulating properties, the change in forest breeding populations influences the conditions of the resort climate-landscape-therapy. The researches conducted in the perfect oak wood of vegetative origin in Beshtaugorsky Forestry Area (BFA) of the RR CMV have shown the reduction of the pedunculate oak in the tree-stand composition during 1984-2014 from 10 to 8 units in the composition: the European ash (1 unit) and the crataegus monogyna (Crataegus monogyna Jacq.), the checker tree (Sorbus torminalis (L.) Crantz), the common pear (Pyrus communis L.) have appeared [2]. The rate of the pedunculate oak decreased from 10 units to 9 in the perfect planting of the pedunculate oak of the artificial origin (Mashuk section of the forestry of BFA of the RR CMV) during 1986-2016. Among accompanying breeds there was the English field maple (Acer campestre L.), the Chinese elm in singular (Ulmus parvifolia Jacq.), the single-seed hawthorn. The reliable regrowth (4C3Fe3Ac+Q+Cm+Pc+Up) in number of 3,9 thousand pieces/hectare defines the perspective of complete replacement of the oak crop in the future on planting with dominance of the hornbeam and the involvement of the ash-tree and the English

Assessment of Factors that Influence the Recruitment of Majors from Introductory Geology Classes

Science.gov (United States)

Hoisch, T. D.; Bowie, J. I.

2009-12-01

preliminary finding of this study is that administering surveys may have the beneficial unintended consequence of inspiring students in introductory classes to reconsider their choice of major. From the Fall 2007 semester to the Spring 2008 semester, 14 of 573 introductory students or 2.4% continued into a geology course that can serve as the second course in the major, whereas from the Fall 2008 semester to the Spring 2009 semester, 24 of 609 students or 4.0% continued, a 67% increase in the rate of continuation. One possible explanation for the dramatic increase is that surveys were administered to students in the introductory classes in Fall 2008 but not in Fall 2007. If administering surveys was in fact the cause of the increase in the continuation rate, then we may have encountered a “Hawthorne effect;” that is, a situation in which the condition of being studied causes subjects to change their behavior. The process of taking the survey may have caused students to reconsider their choice of major, although this was not the intended purpose or design of the surveys.

Heart and Stroke Foundation of Ontario (HSFO high blood pressure strategy's hypertension management initiative study protocol

Directory of Open Access Journals (Sweden)

Von Sychowski Shirley

2008-12-01

community pharmacists across the 11 communities throughout the province of Ontario. The 11 primary care sites will be divided into immediate and delayed groups based on geography and the use of an electronic versus a traditional chart patient record. Discussion Initial consideration was given to randomizing the groups, however, for a number of reasons, this was deemed to not be possible. In order to ensure that the sites in the immediate intervention and delayed intervention groups are not different from each other, the sites will be assigned to the intervention groups manually to ensure a distribution of the variables as evenly as possible. Given that HSFO approached this particular group of health care providers to participate in a program relating to hypertension, this may have heightened their awareness of the issue and affected their management of patients with hypertension. Thus, data will be collected to allow an assessment of previous practice patterns and determine any impact of the Hawthorne Effect. Trial registration Clinicaltrials.gov NCT00425828

Benthic flux of nutrients and trace metals in the northern component of San Francisco Bay, California

Science.gov (United States)

Kuwabara, James S.; Topping, Brent R.; Parcheso, Francis; Engelstad, Anita C.; Greene, Valerie E.

2009-01-01

Island, the benthic flux of soluble reactive phosphorus (SRP) was consistently: (1) lower than previously reported for South Bay sites, (2) an order of magnitude lower than oligotrophic Coeur d?Alene Lake, (3) two orders of magnitude lower than determined for eutrophic Upper Klamath Lake, and (4) an order of magnitude or more lower than the estimated summer riverine inputs for SRP (900 to 1,300 kilograms of phosphorous per day (kg-P d-1)). In contrast to fluxes reported for the South Bay, nitrate fluxes were consistently negative (that is, drawn from the water column into the sediment), except for one site with statistically insignificant nitrate fluxes (Site 409 within Suisun Bay). The most negative nitrate flux (-7.3?0.1 mmole m-2d-1) was observed within Grizzly Bay (Site 416). Observed nitrate fluxes bracketed the estimated summer fluvial flux of nitrate (3,500 to 5,000 kg-N d-1). With the exception of the two Grizzly Bay sites (416 and 417), the consistently positive benthic flux of ammonia generally counteracted the negative flux of nitrate to yield a net balance of dissolved inorganic nitrogen. Ammonia benthic fluxes extrapolated for Suisun Bay ranged from 320 kg-N d-1 (Site SSB009 near the entrance to Honker Bay) to 1,900 kg-N d-1 (Montezuma Island). These values represent a significant ammonia source to the water column relative to summer riverine inputs (approximately 400 to 600 kg-N d-1). Dissolved silica also displayed a consistently positive benthic flux, except for Site 409 within Suisun Bay, which showed insignificant fluxes (also insignificant for nitrate and SRP). As with the nitrate fluxes, Grizzly Bay and Browns Island sites yielded the highest dissolved silica fluxes (1.3?1.2 to 2.5?0.6 mmole m-2d-1, respectively). These initial diffusive-flux estimates are greater than those measured in the South Bay using core-incubation experiments, which include bioturbation and bioirrigation effects, but they are nevertheless probably one to t

Two Types of Belief Report

Directory of Open Access Journals (Sweden)

Michael Hegarty

2010-12-01

-122. Oxford: Oxford University Press.DeRose, K. 1991. ‘Epistemic possibilities’. The Philosophical Review 100: 581–605.http://dx.doi.org/10.2307/2185175Eckhardt, R. 2005. ‘Too poor to mention: Subminimal eventualities and negative polarity items’. In C. Maienborn & A. Wöllstein (eds. ‘Event Arguments: Foundations and Applications’, 301–330. Tübingen: Max Niemeyer Verlag.Eckhardt, R. 2008. ‘The lower part of event ontology’. In J. Dölling, T. Heyde-Zybatow & M. Schäfer (eds. ‘Event Structures in Linguistic Form and Interpretation’, 477–491. Berlin: Walter de Gruyter.Egan, A. 2005. ‘Epistemic modals, relativism, and assertion’. In J. Gajewski, V. Hacquard, B. Nickel & S. Yalcin (eds. ‘New Work on Modality, MIT Working Papers in Linguistics v.51’, 35–62. MIT.Egan, A., Hawthorne, J. & Weatherson, B. 2005. ‘Epistemic modals in context’. In G. Preyer & G. Peter (eds. ‘Contextualism in Philosophy: Knowledge, Meaning and Truth’, 131–170. Oxford: Oxford University Press.Hacquard, V. 2006. Aspects of Modality. Ph.D. thesis, MIT.Hacquard, V. 2010. ‘On the event relativity of modal auxiliaries’. Natural Language Semantics 18: 79–114.http://dx.doi.org/10.1007/s11050-010-9056-4Heim, I. 1992. ‘Presupposition projection and the semantics of attitude verbs’. Journal of Semantics 9: 183–221.http://dx.doi.org/10.1093/jos/9.3.183Heim, I. & Kratzer, A. 1998. Semantics in Generative Grammar. Blackwell Publishers.Higginbotham, J. 1983. ‘The logic of perceptual reports: An extensional alternative to Situation Semantics’. The Journal of Philosophy 80: 100–127.http://dx.doi.org/10.2307/2026237Higginbotham, J. 1985. ‘On Semantics’. Linguistic Inquiry 16: 547–593.Higginbotham, J. 1989. ‘Elucidations of Meaning’. Linguistics and Philosophy 12: 465–517.http://dx.doi.org/10.1007/BF00632473Higginbotham, J. 2000. ‘On events in linguistic semantics’. In J. Higginbotham, F. Pianesi & A. C. Varzi (eds. ‘Speaking of Events�

Ore genesis constraints on the Idaho Cobalt Belt from fluid inclusion gas, noble gas isotope, and ion ratio analyses

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Hofstra, Albert H.; Landis, Gary P.

2012-01-01

38Ar produced by nucleogenic production from 41K. In contrast, some ore and gangue minerals yield significant SO2 and have low RH and RS values of a more oxidized fluid. Three extracts from gangue quartz have high helium R/RA values indicative of a mantle source and neon isotope compositions that require nucleogenic production of 22Ne in fluorite from U ± Th decay. Two extracts from gangue quartz have estimated 40K/40Ar that permit a Precambrian age. Extracts from gangue quartz in three different ore zones are biased toward the hypersaline population of inclusions and have a tight range of ion ratios (Na, K, NH4, Cl, Br, F) suggestive of a single fluid. Their Na, Cl, Br ratios suggest this fluid was a mixture of magmatic and basinal brine. Na-K-Ca temperatures (279°-347°C) are similar to homogenization temperatures of hypersaline inclusions. The high K/Na of the brine may be due to albitization of K silicate minerals in country rocks. Influx of K-rich brines is consistent with the K metasomatism necessary to form gangue biotite with high Cl. An extract from a post-ore quartz vein is distinct and has Na, Cl, Br ratios that resemble metamorphic fluids in Cretaceous silver veins of the Coeur d'Alene district in the Belt Basin. The results show that in some samples, for certain components, it is possible to "see through" the Cretaceous metamorphic overprint. Of great import for genetic models, the volatiles trapped in gangue quartz have 3He derived from a mantle source and 22Ne derived from fluorite, both of which may be attributed to nearby ~1377 Ma basalt-rhyolite magmatism. The brine trapped in gangue quartz is a mixture of magmatic fluid and evaporated seawater. The former requires a granitic intrusion that is present in the bimodal intrusive complex, and the latter equatorial paleolatitudes that existed in the Mesoproterozoic. The results permit genetic models involving heat and fluids from the neighboring bimodal plutonic complex and convection of basinal brine

"Where did my data layer come from?" The semantics of data release

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Leadbetter, Adam; Buck, Justin

2015-04-01

can be seen as an indicator of trust through "benevolence". A technical document citing the dataset may then be informed by the dataset release or the dataset description paper. These citations may show the "competence" (in terms of a trust model) of the original datasets, and the dataset description papers or other technical articles show the integrity of the dataset. The synthesised logical model has been represented in freely available ontologies, such that data layers can be annotated with metadata about their provenance and stage within the data release lifecycle before incorporation into a cyber-GIS, in which distributed data providers provide for a collaborative research environment. References Giarlo, M. (2013). Academic libraries as data quality hubs. Journal of Librarianship and Scholarly Communication 1(3): eP1059. doi: 10.7710/2162-3309.1059 Leadbetter, A. (2015). Examining trust in collaborative research networks. In P. Diviacco, P. Fox, C. Pshenichny, and A. Leadbetter (Eds.) Collaborative Knowledge in Scientific Research Networks, Hershey, PA: IGI Global. doi: 10.4018/978-1-4666-6567-5.ch002 Margulis, L., Corner, J. and Hawthorne, B. (Editors), 2006. Ian McHarg: conversations with students. Dwelling with nature. New York, NY: Princeton Architectural Press. Parsons, M., and Fox, P. (2013). Is data publication the right metaphor? Data Science Journal 12, 32-46. doi:10.2481/dsj.WDS-042 Reinsfelder, T. (2012). Open access publishing practices in a complex environment: conditions, barriers and bases of power. Journal of Librarianship and Scholarly Communication 1(1): eP1029. doi: 10.7710/2162-3309.1029

Medical and health economic evaluation of prevention- and control measures related to MRSA infections or -colonisations at hospitals

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Korczak, Dieter

2010-03-01

internal and external validity of the studies is too weak to evaluate single interventions. Hygienic measurements prove to be effective in combination with other measurements. But it cannot be said which of the single measurements (gloves, washing hands, wearing gowns or masks has the strongest effect on the reduction of MRSA. It is irritating that there are high differences in the compliance concerning hand hygiene between different studies. A general decolonisation is questionable for different reasons: first because of the side-effects for patients, second because of the high rate of spontaneous remissions in the untreated control group, third because of the differentiated process from colonisation to infection. Severalfold Hawthorne effects have been reported. One of them is that the competition between hospitals to reduce MRSA-rates leads already to a reduction. Conclusions: It is evident that selective screening programs of risk patients considering the particular MRSA-prevalence are of use. The application of rapid tests seems to be only recommendable for risk patients and a high MRSA-prevalence. The improvement of the compliance of hand hygiene should be the basis of any prevention strategy. Training of staff members (with feedback mechanisms is effective to improve compliance and to optimise the use of antibiotics. Antibiotic management programs are effective as well. Obviously multimodal approaches can lead to overadditive effects. Therefore the catalogue of preventive and control measurements has to be further evaluated. Good cost-efficacy studies are missing in Germany. The psychosocial effects of MRSA-infections are not researched in Germany. There is only punctual information on the risk management of hospitals.

Medical and health economic evaluation of prevention- and control measures related to MRSA infections or -colonisations at hospitals.

Science.gov (United States)

Korczak, Dieter; Schöffmann, Christine

2010-03-16

. Hygienic measurements prove to be effective in combination with other measurements. But it cannot be said which of the single measurements (gloves, washing hands, wearing gowns or masks) has the strongest effect on the reduction of MRSA. It is irritating that there are high differences in the compliance concerning hand hygiene between different studies. A general decolonisation is questionable for different reasons: first because of the side-effects for patients, second because of the high rate of spontaneous remissions in the untreated control group, third because of the differentiated process from colonisation to infection. Severalfold Hawthorne effects have been reported. One of them is that the competition between hospitals to reduce MRSA-rates leads already to a reduction. It is evident that selective screening programs of risk patients considering the particular MRSA-prevalence are of use. The application of rapid tests seems to be only recommendable for risk patients and a high MRSA-prevalence. The improvement of the compliance of hand hygiene should be the basis of any prevention strategy. Training of staff members (with feedback mechanisms) is effective to improve compliance and to optimise the use of antibiotics. Antibiotic management programs are effective as well. Obviously multimodal approaches can lead to overadditive effects. Therefore the catalogue of preventive and control measurements has to be further evaluated. Good cost-efficacy studies are missing in Germany. The psychosocial effects of MRSA-infections are not researched in Germany. There is only punctual information on the risk management of hospitals.

Hydrothermal mobilization of pegmatite-hosted REE and Zr at Strange Lake, Canada: A reaction path model

Science.gov (United States)

Gysi, Alexander P.; Williams-Jones, Anthony E.

2013-12-01

, particularly at high temperature (400 °C). The LREE are more mobile than the HREE in saline HCl-bearing fluids due to the greater stability of LREE-chloride complexes. The simulated mineralogy is consistent with the zonation observed in the pegmatites and with fluid-rock interaction at conditions that were rock-buffered in the pegmatite borders (low fluid/rock ratio; and pH > 4) and fluid-buffered in the cores (high fluid/rock ratio; pH ⩽ 2). We propose a model in which saline HCl-HF-bearing fluids created pathways during acidic alteration from the pegmatite cores outward. This led to the mobilization of REE and Zr due to progressive alteration of primary silicate minerals and increased acidity upon cooling. The key requirement for REE and Zr mobilization in peralkaline igneous intrusions is the formation of an acidic subsystem with high fluid/rock ratios that increases the overall permeability of the rocks. In these zones, the extent of late stage hydrothermal redistribution and concentration of REE and Zr depends on the buffering capacity of the rocks and the availability of fluids that may produce autometasomatic rock alteration, interact with external rock units and/or mix with fluids from other sources. b The detection limits of Yb were 1043 ppm for zircon, 380 ppm for gadolinite-group minerals and 380 ppm for REE-F-(CO2)-minerals. bAja et al. (1995). cMigdisov et al. (2011). dTagirov et al. (1997). eTagirov and Schott (2001). fMigdisov et al. (2009) with REE (La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu). b Calculated using the methods of the Chermak and Rimstidt (1989), Berman and Brown (1985) and Holland (1989) with molar volume of arfvedsonite from Hawthorne (1976). cZotov et al. (1998). d GEM-Selektor v.3 database (http://gems.web.psi.ch). eMigdisov et al. (2009).

Book reviews

Directory of Open Access Journals (Sweden)

Redactie KITLV

2012-06-01

Full Text Available The African Diaspora: A History Through Culture, by Patrick Manning (reviewed by Joseph C. Miller Atlas of the Transatlantic Slave Trade, by David Eltis & David Richardson (reviewed by Ted Maris-Wolf Abolition: A History of Slavery and Antislavery, by Seymour Drescher (reviewed by Gregory E. O’Malley Paths to Freedom: Manumission in the Atlantic World, edited by Rosemary Brana-Shute & Randy J. Sparks (reviewed by Matthew Mason You Are All Free: The Haitian Revolution and the Abolition of Slavery, by Jeremy D. Popkin (reviewed by Philippe R. Girard Fighting for Honor: The History of African Martial Arts in the Atlantic World, by T .J. Desch Obi (reviewed by Flávio Gomes & Antonio Liberac Cardoso Simões Pires Working the Diaspora: The Impact of African Labor on the Anglo-American World, 1650-1850, by Frederick C. Knight (reviewed by Walter Hawthorne The Akan Diaspora in the Americas, by Kwasi Konadu (reviewed by Ray Kea Tradition and the Black Atlantic: Critical Theory in the African Diaspora, by Henry Louis Gates Jr. (reviewed by Deborah A. Thomas From Africa to Jamaica: The Making of an Atlantic Slave Society, 1775-1807, by Audra A. Diptee (reviewed by D.A. Dunkley Elections, Violence and the Democratic Process in Jamaica 1944-2007, by Amanda Sives (reviewed by Douglas Midgett Caciques and Cemi Idols: The Web Spun by Taino Rulers between Hispaniola and Puerto Rico, by José R. Oliver (reviewed by Brian D. Bates The Latin American Identity and the African Diaspora: Ethnogenesis in Context, by Antonio Olliz Boyd (reviewed by Dawn F. Stinchcomb Reconstructing Racial Identity and the African Past in the Dominican Republic, by Kimberly Eison Simmons (reviewed by Ginetta E.B. Candelario Haiti and the Haitian Diaspora in the Wider Caribbean, edited by Philippe Zacaïr (reviewed by Catherine Benoît Duvalier’s Ghosts: Race, Diaspora, and U.S. Imperialism in Haitian Literatures, by Jana

Study the Stability of SSR Repeats of pEA29 Plasmid of the Casual Agent of Fire Blight

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S. Baghaee Ravari

2016-02-01

negative, catalase positive and non fluorescent on King's B. The biochemical tests for reduction of nitrate, tween 20 and growth at 36 °C were recorded negative. All E. amylovora strains induced the hypersensitive reaction (HR on tobacco and pelargonium leaves. All phenotypic tests were agreed with standard references. There is no variation in lab expermints. Pathogenicity assay were checked using immature pear fruit in two separate treatments. Inoculation caused water soaking, tissue necrosis and sometimes necrosis in pear samples. No symptoms were observed in the negative controls. There is no variation in this assay. It seems that in most cases, the pEA29 plasmid can modify synthesis of amylovoran, levansucrase and finally affect pathogenicity in the host plant with respect to the environment. All strains were check by agri strips (Bioreba, Switzeland, Reinach in lateral flow immune chromatography to confirm presence of E. amylovora. All strains of E. amylovora amplified a fragment of the expected size using primers A and B. The accuracy of the direct PCr was evaluated by nested PCR using primers AJ75/AJ76. The PCR products were visualized after electrophoresis on 1.2% agarose gels. A 3kb DNA ladder (Fermentas, Lithuania was used as a molecular size marker in all experiments. In order to chracterize SSR units in thi study, part of PstI fragment was amplified by RS1/Rs2 primers. The relevant variability found in the length of the this fragment was explained by a variation in the number of copies of a SSRs of 8 bp, GAATTACA. It is recorded 4 and 8 times in apple and rose plants respectively. Recording the SSRs of 4, 5 and 7 in other hosts including pear, hawthorn and quince may be indicated that under natural conditions, a mixture of E. amylovora strains with different SSR numbers can be caused fire blight. Frequent transffering of bacterial isolats to new nutrient agar medium did not change the SSR units ater three months. Among three testd tretments, keeping in cold

Assessment of a sequential extraction protocol by examining solution chemistry and mineralogical evolution

Science.gov (United States)

Maubec, Nicolas; Pauwels, Hélène; Noël, Hervé; Bourrat, Xavier

2015-04-01

séquentielles et spéciation des éléments trace métalliques dans les sols naturels. Analyse critique. 7, 179-189. Das, A. K., Chakraborty, R., Cervera, M. L., and Delaguardia, M. (1995). Metal speciation in solid matrices. Talanta, 42. Gomez Ariza, J. L., Giraldez, I., Sanchez-Rodas, D., and Morales, E. (2000). Selectivity assessment of a sequential extraction procedure for metal mobility characterization using model phases. Talanta, 52, 545-554. Hickey, M. G., and Kittrick, J. A. (1984). Chemical partitioning of cadmium, copper, nickel and zinc in soils and sediments containing high-levels of heavy metals. Journal of Environmental Quality, 13, 372-376. La Force, M. J., Fendorf, S., Li, G. C., and Rosenzweig, R. F. (1999). Redistribution of trace elements from contaminated sediments of Lake Coeur d'Alene during oxygenation. Journal of Environmental Quality, 28, 1195-1200. Quevauviller, P., Rauret, G., Muntau, H., Ure, A. M., Rubio, R., Lopezsanchez, J. F., Fiedler, H. D., and Griepink, B. (1994). Evaluation of a sequential extraction procedure for the determination of extractable trace-metal contents in sediments. Fresenius Journal of Analytical Chemistry, 349. Rauret, G. (1998). Extraction procedures for the determination of heavy metals in contaminated soil and sediment. Talanta, 46(3), 449-455. Sterckeman, T., Douay, F., Baize, D., Fourrier, H., Proix, N., and Schvartz, C. (2004). Factors affecting trace element concentrations in soils developed on recent marine deposits from northern France. Applied Geochemistry, 19. Tack, F. M. G., and Verloo, M. G. (1995). Chemical speciation and fraéctination in soil and sediment heavy-metal analysis - a review. International Journal of Environmental Analytical Chemistry, 59, 225-238. Tessier, A., Campbell, P. G. C., and Bisson, M. (1979). Sequential extraction procedure for the speciation of particulate trace-metals. Analytical Chemistry, 51. Van Oort, F., Jongmans, A. G., Lamy, I., Baize, D., and Chevallier, P. (2008

Fingerprinting the Milky Way

Science.gov (United States)

2007-03-01

genealogic tree of the Milky Way. This chemical mapping through time and space will be a way to test theoretical models. "The path to an extensive use of chemical tagging is still long," cautions De Silva, "but our study shows that it is possible. When the technique is tested and proven we will be able to get a detailed picture of the way our Galactic cradle formed." More Information The research presented here is discussed in a paper in the Astronomical Journal, volume 133, pages 1161-1175 ("Chemical homogeneity in Collinder 261 and implications for chemical tagging", by G.M. De Silva et al.). The team is composed of Gayandhi De Silva (ESO), Kenneth Freeman, Martin Asplund and Michael Bessell (Mount Stromlo Observatory, Australia), Joss Bland-Hawthorn (Anglo-Australian Observatory, Australia), Remo Collet (Uppsala University, Sweden).

The evaluation of physico-chemical parameters of the Nasrand Plutonic complex by using mineral composition

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Fatemeh Sarjoughian

2017-02-01

Putirka (Putirka, 2008 equations which are assumed to reflect the actual temperature of initial pyroxene crystallization and are usually higher than temperatures obtained by hornblende-plagioclase thermometry. Oxygen fugacity in the granitoid rocks and dioritic dikes is above the Ni-NiO buffer and it is indicated to be -12.9 and 10.5 bars, respectively, by the Ridolfi et al. (Ridolfi et al., 2010 equation. Water contents in the granitoid rocks and dikes are calculated to be about 3.6 and 4.6 wt. % respectively, by the Ridolfi et al. (Ridolfi et al., 2010 equation, i.e. for typically subduction - related environments. References Ague, J.J., 1997. Thermodynamic calculation of emplacement pressures for batholithic rocks, California: Implications for the aluminum-in-hornblende barometer. Geology, 25(6: 563-566. Anderson, J.L. and Smith, D.R., 1995. The effects of temperature and ƒO2 on the Al-in-hornblende barometer. American Mineralogist, 80(5-6: 549-559. Deer, W.A., Howie, R.A. and Zussman, J., 1991. An introduction to the Rock forming minerals. Longman, London, 969 pp. Holland, T. and Blundy, J., 1994. Non-ideal interactions in calcic-amphiboles and their bearing on amphibole-plagioclase thermometry. Contribution to Mineralogy and Petrology, 116(4: 433-447. Leake, B.E., Woolly, A.R., Arps, C.E.S., Birch, W.D., Gilbert, M.C., Grice, J.D., Hawthorne, F.C., Kato, A., Kisch, H.J., Krivovichev, V.G., Linthout, K., Laird, J., Mandarino, J., Maresch, W.V., Nickel, E.h., Rock, N.M.S., Schmucher, J.C., Smith, D.C., Stephenson, N.C.N, Unungaretti, L., Whittaker, E.J.W. and Youzhi G., 1997. Nomenclature of Amphiboles, Report of the Subcommittee on Amphiboles of the International Mineralogical Association Commission on New Minerals Names. Europian Journal of Mineralogy, 9(3: 623-651. Morimoto, N., 1988. Nomenclature of pyroxenes. Fortschr mineral, 66(2: 237–252. Putirka, K.D., 2008. Thermometers and Barometers for Volcanic Systems. Reviews in Mineralogy and Geochemistry, 69(1: 61

Life cycle assessment in support of sustainable transportation

Science.gov (United States)

Eckelman, Matthew J.

2013-06-01

cycle GHG and air pollutant emissions. A related study in Toronto on life cycle energy use and GHG emissions for high- and low-density development strategies found a ~60% difference in GHG emissions, largely due to transportation (Norman et al 2006). System dynamics and agent-based models may complement LCA in capturing long-term effects of transportation strategies as they are inherently dynamic (Stepp et al 2009), and can internalize spatially resolved decisions about where to settle and work (Waddell 2002). Transportation planning decisions have both direct and indirect, spatially distributed, often long-term effects on our health and our environment. The accompanying work by Chester et al (2013) provides a well-documented case study that highlights the potential of LCA as a rich source of decision support. References Chester M, Pincetl S, Elizabeth Z, Eisenstein W and Matute J 2013 Infrastructure and automobile shifts: positioning transit to reduce life-cycle environmental impacts for urban sustainability goals Environ. Res. Lett. 8 015041 Chester M V and Horvath A 2009 Environmental assessment of passenger transportation should include infrastructure and supply chains Environ. Res. Lett. 4 024008 Fargione J, Hill J, Tilman D, Polasky S and Hawthorne P 2008 Land clearing and the biofuel carbon debt Science 319 1235-8 Kennedy C, Steinberger J, Gasson B, Hansen Y, Hillman T, Havránek M, Pataki D, Phdungsilp A, Ramaswami A and Mendez G V 2009 Greenhouse gas emissions from global cities Environ. Sci. Technol. 43 7297-302 Kunstler J H 1994 Geography of Nowhere: The Rise and Decline of America's Man-Made Landscape (New York: Free Press) Mashayekh Y, Jaramillo P, Samaras C, Hendrickson C T, Blackhurst M, MacLean H L and Matthews H S 2012 Potentials for sustainable transportation in cities to alleviate climate change impacts Environ. Sci. Technol. 46 2529-37 Mutel C L and Hellweg S 2009 Regionalized life cycle assessment: computational methodology and application to

The source of phosphate in the oxidation zone of ore deposits: Evidence from oxygen isotope compositions of pyromorphite

Science.gov (United States)

Burmann, Fabian; Keim, Maximilian F.; Oelmann, Yvonne; Teiber, Holger; Marks, Michael A. W.; Markl, Gregor

2013-12-01

, toothpaste and as a release of waste water treatment plants (Young et al., 2009). Anthropogenic effects will not be discussed further in the following. On this basis, we consider three different cases of pyromorphite formation as illustrated on the conceptual scheme of Fig. 1. Case 1: Pyromorphite grown recently (within the last hundreds of years) on rock surfaces in former mines. Both, phosphate released geochemically from igneous rocks and phosphate released biologically during leaching from litter/lysis of microbial cells and soil organic matter decomposition are possible sources. Case 2: Pyromorphite formation on mine dumps, below vegetation (recent, during tens to hundreds of years). Based on the specific setting of these samples investigated here (they were found exclusively below a large fern; see more details in the section on sample description), biologically-mediated P release provides the phosphate for pyromorphite growth. Case 3: Pyromorphite growth in the oxidized zones of ore bodies prior to human interference. Most samples of our study belong to this case.Phosphorus generally forms very strong covalent bonds (Huminicki and Hawthorne, 2002) and there is only negligible exchange of oxygen isotopes between phosphate and ambient water under most near-surface conditions without biological activity (Winter et al., 1940; Longinelli, 1965). The only important exchange of oxygen isotopes between phosphate and ambient water involves biological activity and the oxygen isotope composition of phosphate (δ18OP) may be modified by different enzymatic/cellular processes. Once phosphate is taken up by organisms, intracellular pyrophosphatase mediates internal P cycling. This is associated with a temperature-dependent equilibrium isotope fractionation due to the reversible exchange of O atoms between the phosphate molecule and cell water. As a result the δ18OP is equilibrated with the ambient water, and the equilibrium temperature can be calculated following the revised