Personalized Pseudonyms for Servers in the Cloud

Directory of Open Access Journals (Sweden)

Xiao Qiuyu

2017-10-01

Full Text Available A considerable and growing fraction of servers, especially of web servers, is hosted in compute clouds. In this paper we opportunistically leverage this trend to improve privacy of clients from network attackers residing between the clients and the cloud: We design a system that can be deployed by the cloud operator to prevent a network adversary from determining which of the cloud’s tenant servers a client is accessing. The core innovation in our design is a PoPSiCl (pronounced “popsicle”, a persistent pseudonym for a tenant server that can be used by a single client to access the server, whose real identity is protected by the cloud from both passive and active network attackers. When instantiated for TLS-based access to web servers, our design works with all major browsers and requires no additional client-side software and minimal changes to the client user experience. Moreover, changes to tenant servers can be hidden in supporting software (operating systems and web-programming frameworks without imposing on web-content development. Perhaps most notably, our system boosts privacy with minimal impact to web-browsing performance, after some initial setup during a user’s first access to each web server.

Using a centralised database system and server in the European Union Framework Programme 7 project SEPServer

Science.gov (United States)

Heynderickx, Daniel

2012-07-01

The main objective of the SEPServer project (EU FP7 project 262773) is to produce a new tool, which greatly facilitates the investigation of solar energetic particles (SEPs) and their origin: a server providing SEP data, related electromagnetic (EM) observations and analysis methods, a comprehensive catalogue of the observed SEP events, and educational/outreach material on solar eruptions. The project is coordinated by the University of Helsinki. The project will combine data and knowledge from 11 European partners and several collaborating parties from Europe and US. The datasets provided by the consortium partners are collected in a MySQL database (using the ESA Open Data Interface under licence) on a server operated by DH Consultancy, which also hosts a web interface providing browsing, plotting and post-processing and analysis tools developed by the consortium, as well as a Solar Energetic Particle event catalogue. At this stage of the project, a prototype server has been established, which is presently undergoing testing by users inside the consortium. Using a centralized database has numerous advantages, including: homogeneous storage of the data, which eliminates the need for dataset specific file access routines once the data are ingested in the database; a homogeneous set of metadata describing the datasets on both a global and detailed level, allowing for automated access to and presentation of the various data products; standardised access to the data in different programming environments (e.g. php, IDL); elimination of the need to download data for individual data requests. SEPServer will, thus, add value to several space missions and Earth-based observations by facilitating the coordinated exploitation of and open access to SEP data and related EM observations, and promoting correct use of these data for the entire space research community. This will lead to new knowledge on the production and transport of SEPs during solar eruptions and facilitate the

3Drefine: an interactive web server for efficient protein structure refinement.

Science.gov (United States)

Bhattacharya, Debswapna; Nowotny, Jackson; Cao, Renzhi; Cheng, Jianlin

2016-07-08

3Drefine is an interactive web server for consistent and computationally efficient protein structure refinement with the capability to perform web-based statistical and visual analysis. The 3Drefine refinement protocol utilizes iterative optimization of hydrogen bonding network combined with atomic-level energy minimization on the optimized model using a composite physics and knowledge-based force fields for efficient protein structure refinement. The method has been extensively evaluated on blind CASP experiments as well as on large-scale and diverse benchmark datasets and exhibits consistent improvement over the initial structure in both global and local structural quality measures. The 3Drefine web server allows for convenient protein structure refinement through a text or file input submission, email notification, provided example submission and is freely available without any registration requirement. The server also provides comprehensive analysis of submissions through various energy and statistical feedback and interactive visualization of multiple refined models through the JSmol applet that is equipped with numerous protein model analysis tools. The web server has been extensively tested and used by many users. As a result, the 3Drefine web server conveniently provides a useful tool easily accessible to the community. The 3Drefine web server has been made publicly available at the URL: http://sysbio.rnet.missouri.edu/3Drefine/. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

The NCAR Research Data Archive's Hybrid Approach for Data Discovery and Access

Science.gov (United States)

Schuster, D.; Worley, S. J.

2013-12-01

The NCAR Research Data Archive (RDA http://rda.ucar.edu) maintains a variety of data discovery and access capabilities for it's 600+ dataset collections to support the varying needs of a diverse user community. In-house developed and standards-based community tools offer services to more than 10,000 users annually. By number of users the largest group is external and access the RDA through web based protocols; the internal NCAR HPC users are fewer in number, but typically access more data volume. This paper will detail the data discovery and access services maintained by the RDA to support both user groups, and show metrics that illustrate how the community is using the services. The distributed search capability enabled by standards-based community tools, such as Geoportal and an OAI-PMH access point that serves multiple metadata standards, provide pathways for external users to initially discover RDA holdings. From here, in-house developed web interfaces leverage primary discovery level metadata databases that support keyword and faceted searches. Internal NCAR HPC users, or those familiar with the RDA, may go directly to the dataset collection of interest and refine their search based on rich file collection metadata. Multiple levels of metadata have proven to be invaluable for discovery within terabyte-sized archives composed of many atmospheric or oceanic levels, hundreds of parameters, and often numerous grid and time resolutions. Once users find the data they want, their access needs may vary as well. A THREDDS data server running on targeted dataset collections enables remote file access through OPENDAP and other web based protocols primarily for external users. In-house developed tools give all users the capability to submit data subset extraction and format conversion requests through scalable, HPC based delayed mode batch processing. Users can monitor their RDA-based data processing progress and receive instructions on how to access the data when it is

User-Friendly Data Servers for Climate Studies at the Asia-Pacific Data-Research Center (APDRC)

Science.gov (United States)

Yuan, G.; Shen, Y.; Zhang, Y.; Merrill, R.; Waseda, T.; Mitsudera, H.; Hacker, P.

2002-12-01

The APDRC was recently established within the International Pacific Research Center (IPRC) at the University of Hawaii. The APDRC mission is to increase understanding of climate variability in the Asia-Pacific region by developing the computational, data-management, and networking infrastructure necessary to make data resources readily accessible and usable by researchers, and by undertaking data-intensive research activities that will both advance knowledge and lead to improvements in data preparation and data products. A focus of recent activity is the implementation of user-friendly data servers. The APDRC is currently running a Live Access Server (LAS) developed at NOAA/PMEL to provide access to and visualization of gridded climate products via the web. The LAS also allows users to download the selected data subsets in various formats (such as binary, netCDF and ASCII). Most of the datasets served by the LAS are also served through our OPeNDAP server (formerly DODS), which allows users to directly access the data using their desktop client tools (e.g. GrADS, Matlab and Ferret). In addition, the APDRC is running an OPeNDAP Catalog/Aggregation Server (CAS) developed by Unidata at UCAR to serve climate data and products such as model output and satellite-derived products. These products are often large (> 2 GB) and are therefore stored as multiple files (stored separately in time or in parameters). The CAS remedies the inconvenience of multiple files and allows access to the whole dataset (or any subset that cuts across the multiple files) via a single request command from any DODS enabled client software. Once the aggregation of files is configured at the server (CAS), the process of aggregation is transparent to the user. The user only needs to know a single URL for the entire dataset, which is, in fact, stored as multiple files. CAS even allows aggregation of files on different systems and at different locations. Currently, the APDRC is serving NCEP, ECMWF

4DGeoBrowser: A Web-Based Data Browser and Server for Accessing and Analyzing Multi-Disciplinary Data

National Research Council Canada - National Science Library

Lerner, Steven

2001-01-01

.... Once the information is loaded onto a Geobrowser server the investigator-user is able to login to the website and use a set of data access and analysis tools to search, plot, and display this information...

To the Geoportal and Beyond! Preparing the Earth Observing Laboratory's Datasets for Inter-Repository Discovery

Science.gov (United States)

Gordon, S.; Dattore, E.; Williams, S.

2014-12-01

Even when a data center makes it's datasets accessible, they can still be hard to discover if the user is unaware of the laboratory or organization the data center supports. NCAR's Earth Observing Laboratory (EOL) is no exception. In response to this problem and as an inquiry into the feasibility of inter-connecting all of NCAR's repositories at a discovery layer, ESRI's Geoportal was researched. It was determined that an implementation of Geoportal would be a good choice to build a proof of concept model of inter-repository discovery around. This collaborative project between the University of Illinois and NCAR is coordinated through the Data Curation Education in Research Centers program. This program is funded by the Institute of Museum and Library Services.Geoportal is open source software. It serves as an aggregation point for metadata catalogs of earth science datasets, with a focus on geospatial information. EOL's metadata is in static THREDDS catalogs. Geoportal can only create records from a THREDDS Data Server. The first step was to make EOL metadata more accessible by utilizing the ISO 19115-2 standard. It was also decided to create DIF records so EOL datasets could be ingested in NASA's Global Change Master Directory (GCMD). To offer records for harvest, it was decided to develop an OAI-PMH server. To make a compliant server, the OAI_DC standard was also implemented. A server was written in Perl to serve a set of static records. We created a sample set of records in ISO 19115-2, FGDC, DIF, and OAI_DC. We utilized GCMD shared vocabularies to enhance discoverability and precision. The proof of concept was tested and verified by having another NCAR laboratory's Geoportal harvest our sample set. To prepare for production, templates for each standard were developed and mapped to the database. These templates will help the automated creation of records. Once the OAI-PMH server is re-written in a Grails framework a dynamic representation of EOL's metadata will

EarthServer - 3D Visualization on the Web

Science.gov (United States)

Wagner, Sebastian; Herzig, Pasquale; Bockholt, Ulrich; Jung, Yvonne; Behr, Johannes

2013-04-01

EarthServer (www.earthserver.eu), funded by the European Commission under its Seventh Framework Program, is a project to enable the management, access and exploration of massive, multi-dimensional datasets using Open GeoSpatial Consortium (OGC) query and processing language standards like WCS 2.0 and WCPS. To this end, a server/client architecture designed to handle Petabyte/Exabyte volumes of multi-dimensional data is being developed and deployed. As an important part of the EarthServer project, six Lighthouse Applications, major scientific data exploitation initiatives, are being established to make cross-domain, Earth Sciences related data repositories available in an open and unified manner, as service endpoints based on solutions and infrastructure developed within the project. Clients technology developed and deployed in EarthServer ranges from mobile and web clients to immersive virtual reality systems, all designed to interact with a physically and logically distributed server infrastructure using exclusively OGC standards. In this contribution, we would like to present our work on a web-based 3D visualization and interaction client for Earth Sciences data using only technology found in standard web browsers without requiring the user to install plugins or addons. Additionally, we are able to run the earth data visualization client on a wide range of different platforms with very different soft- and hardware requirements such as smart phones (e.g. iOS, Android), different desktop systems etc. High-quality, hardware-accelerated visualization of 3D and 4D content in standard web browsers can be realized now and we believe it will become more and more common to use this fast, lightweight and ubiquitous platform to provide insights into big datasets without requiring the user to set up a specialized client first. With that in mind, we will also point out some of the limitations we encountered using current web technologies. Underlying the EarthServer web client

Web-accessible molecular modeling with Rosetta: The Rosetta Online Server that Includes Everyone (ROSIE).

Science.gov (United States)

Moretti, Rocco; Lyskov, Sergey; Das, Rhiju; Meiler, Jens; Gray, Jeffrey J

2018-01-01

The Rosetta molecular modeling software package provides a large number of experimentally validated tools for modeling and designing proteins, nucleic acids, and other biopolymers, with new protocols being added continually. While freely available to academic users, external usage is limited by the need for expertise in the Unix command line environment. To make Rosetta protocols available to a wider audience, we previously created a web server called Rosetta Online Server that Includes Everyone (ROSIE), which provides a common environment for hosting web-accessible Rosetta protocols. Here we describe a simplification of the ROSIE protocol specification format, one that permits easier implementation of Rosetta protocols. Whereas the previous format required creating multiple separate files in different locations, the new format allows specification of the protocol in a single file. This new, simplified protocol specification has more than doubled the number of Rosetta protocols available under ROSIE. These new applications include pK a determination, lipid accessibility calculation, ribonucleic acid redesign, protein-protein docking, protein-small molecule docking, symmetric docking, antibody docking, cyclic toxin docking, critical binding peptide determination, and mapping small molecule binding sites. ROSIE is freely available to academic users at http://rosie.rosettacommons.org. © 2017 The Protein Society.

Optimal Configuration of Fault-Tolerance Parameters for Distributed Server Access

DEFF Research Database (Denmark)

Daidone, Alessandro; Renier, Thibault; Bondavalli, Andrea

2013-01-01

Server replication is a common fault-tolerance strategy to improve transaction dependability for services in communications networks. In distributed architectures, fault-diagnosis and recovery are implemented via the interaction of the server replicas with the clients and other entities...... model using stochastic activity networks (SAN) for the evaluation of performance and dependability metrics of a generic transaction-based service implemented on a distributed replication architecture. The composite SAN model can be easily adapted to a wide range of client-server applications deployed...

BEBAN JARINGAN SAAT MENGAKSES EMAIL DARI BEBERAPA MAIL SERVER

Directory of Open Access Journals (Sweden)

Husni Thamrin

2017-01-01

Full Text Available Expensive internet facilities require prudent in its use both as a source of information and communication media. This paper discusses observations of the perceived burden of network bandwidth when accessing some of the mail server using a webmail application. Mail server in question consists of three commercial server and 2 non-commercial server. Data when it download home page, while logged in, open the email, and during idle logout recorded with sniffer Wireshark. Observations in various situations and scenarios indicate that access Yahoo email gives the network load is very high while the SquirrelMail gives the network load is very low than 5 other mail servers. For an institution, use a local mail server (institutional is highly recommended in the context of banddwidth savings.

NExT server

CERN Document Server

1989-01-01

The first website at CERN - and in the world - was dedicated to the World Wide Web project itself and was hosted on Berners-Lee's NeXT computer. The website described the basic features of the web; how to access other people's documents and how to set up your own server. This NeXT machine - the original web server - is still at CERN. As part of the project to restore the first website, in 2013 CERN reinstated the world's first website to its original address.

The design and implementation about the project of optimizing proxy servers

International Nuclear Information System (INIS)

Wu Ling; Liu Baoxu

2006-01-01

Proxy server is an important facility in the network of an organization, which play an important role in security and access control and accelerating access of Internet. This article introduces the action of proxy servers, and expounds the resolutions to optimize proxy servers at IHEP: integration, dynamic domain name resolves and data synchronization. (authors)

A Standard for Sharing and Accessing Time Series Data: The Heliophysics Application Programmers Interface (HAPI) Specification

Science.gov (United States)

Vandegriff, J. D.; King, T. A.; Weigel, R. S.; Faden, J.; Roberts, D. A.; Harris, B. T.; Lal, N.; Boardsen, S. A.; Candey, R. M.; Lindholm, D. M.

2017-12-01

We present the Heliophysics Application Programmers Interface (HAPI), a new interface specification that both large and small data centers can use to expose time series data holdings in a standard way. HAPI was inspired by the similarity of existing services at many Heliophysics data centers, and these data centers have collaborated to define a single interface that captures best practices and represents what everyone considers the essential, lowest common denominator for basic data access. This low level access can serve as infrastructure to support greatly enhanced interoperability among analysis tools, with the goal being simplified analysis and comparison of data from any instrument, model, mission or data center. The three main services a HAPI server must perform are 1. list a catalog of datasets (one unique ID per dataset), 2. describe the content of one dataset (JSON metadata), and 3. retrieve numerical content for one dataset (stream the actual data). HAPI defines both the format of the query to the server, and the response from the server. The metadata is lightweight, focusing on use rather than discovery, and the data format is a streaming one, with Comma Separated Values (CSV) being required and binary or JSON streaming being optional. The HAPI specification is available at GitHub, where projects are also underway to develop reference implementation servers that data providers can adapt and use at their own sites. Also in the works are data analysis clients in multiple languages (IDL, Python, Matlab, and Java). Institutions which have agreed to adopt HAPI include Goddard (CDAWeb for data and CCMC for models), LASP at the University of Colorado Boulder, the Particles and Plasma Interactions node of the Planetary Data System (PPI/PDS) at UCLA, the Plasma Wave Group at the University of Iowa, the Space Sector at the Johns Hopkins Applied Physics Lab (APL), and the tsds.org site maintained at George Mason University. Over the next year, the adoption of a

Review of access, licenses and understandability of open datasets used in hydrology research

Science.gov (United States)

Falkenroth, Esa; Arheimer, Berit; Lagerbäck Adolphi, Emma

2015-04-01

could be that many data sets have been assembled by research project that no longer are funded. Hence, their server infrastructure would be less maintained compared to large-scale operational services. Regarding understandability of the data sets, the issues encountered were mainly due to incomplete documentation or metadata and problems with decoding binary formats. Ideally, open data sets should be represented in well-known formats and they should be accompanied with sufficient documentation so the data set can be understood. Furthermore, machine-readable format would be preferrable. Here, the development efforts on Water ML and NETCDF and other standards should improve understandability of data sets over time but in this review, only a few data sets were provided in these wellknown formats. Instead, the majority of datasets were stored in various text-based or binary formats or even document-oriented formats such as PDF. For some binary formats, we could not find information on what software was necessary to decipher the files. Other domains such as meteorology have long-standing traditions of operational data exchange format whereas hydrology research is still quite fragmented and the data exchange is usually done on a case-by-case basis. With the increased sharing of open data there is a good chance the situation will improve for data sets used in hydrology research. Finally, regarding licensce issue, a high number of data sets did not have a clear statement on terms of use and limitation for access. In most cases the provider could be contacted regarding licensing issues.

The case for developing publicly-accessible datasets for health services research in the Middle East and North Africa (MENA region

Directory of Open Access Journals (Sweden)

El-Jardali Fadi

2009-10-01

Full Text Available Abstract Background The existence of publicly-accessible datasets comprised a significant opportunity for health services research to evolve into a science that supports health policy making and evaluation, proper inter- and intra-organizational decisions and optimal clinical interventions. This paper investigated the role of publicly-accessible datasets in the enhancement of health care systems in the developed world and highlighted the importance of their wide existence and use in the Middle East and North Africa (MENA region. Discussion A search was conducted to explore the availability of publicly-accessible datasets in the MENA region. Although datasets were found in most countries in the region, those were limited in terms of their relevance, quality and public-accessibility. With rare exceptions, publicly-accessible datasets - as present in the developed world - were absent. Based on this, we proposed a gradual approach and a set of recommendations to promote the development and use of publicly-accessible datasets in the region. These recommendations target potential actions by governments, researchers, policy makers and international organizations. Summary We argue that the limited number of publicly-accessible datasets in the MENA region represents a lost opportunity for the evidence-based advancement of health systems in the region. The availability and use of publicly-accessible datasets would encourage policy makers in this region to base their decisions on solid representative data and not on estimates or small-scale studies; researchers would be able to exercise their expertise in a meaningful manner to both, policy makers and the public. The population of the MENA countries would exercise the right to benefit from locally- or regionally-based studies, versus imported and in 'best cases' customized ones. Furthermore, on a macro scale, the availability of regionally comparable publicly-accessible datasets would allow for the

Building mail server on distributed computing system

International Nuclear Information System (INIS)

Akihiro Shibata; Osamu Hamada; Tomoko Oshikubo; Takashi Sasaki

2001-01-01

The electronic mail has become the indispensable function in daily job, and the server stability and performance are required. Using DCE and DFS we have built the distributed electronic mail sever, that is, servers such as SMTP, IMAP are distributed symmetrically, and provides the seamless access

EarthServer: Visualisation and use of uncertainty as a data exploration tool

Science.gov (United States)

Walker, Peter; Clements, Oliver; Grant, Mike

2013-04-01

The Ocean Science/Earth Observation community generates huge datasets from satellite observation. Until recently it has been difficult to obtain matching uncertainty information for these datasets and to apply this to their processing. In order to make use of uncertainty information when analysing "Big Data" we need both the uncertainty itself (attached to the underlying data) and a means of working with the combined product without requiring the entire dataset to be downloaded. The European Commission FP7 project EarthServer (http://earthserver.eu) is addressing the problem of accessing and ad-hoc analysis of extreme-size Earth Science data using cutting-edge Array Database technology. The core software (Rasdaman) and web services wrapper (Petascope) allow huge datasets to be accessed using Open Geospatial Consortium (OGC) standard interfaces including the well established standards, Web Coverage Service (WCS) and Web Map Service (WMS) as well as the emerging standard, Web Coverage Processing Service (WCPS). The WCPS standard allows the running of ad-hoc queries on any of the data stored within Rasdaman, creating an infrastructure where users are not restricted by bandwidth when manipulating or querying huge datasets. The ESA Ocean Colour - Climate Change Initiative (OC-CCI) project (http://www.esa-oceancolour-cci.org/), is producing high-resolution, global ocean colour datasets over the full time period (1998-2012) where high quality observations were available. This climate data record includes per-pixel uncertainty data for each variable, based on an analytic method that classifies how much and which types of water are present in a pixel, and assigns uncertainty based on robust comparisons to global in-situ validation datasets. These uncertainty values take two forms, Root Mean Square (RMS) and Bias uncertainty, respectively representing the expected variability and expected offset error. By combining the data produced through the OC-CCI project with the

Creating Large Scale Database Servers

International Nuclear Information System (INIS)

Becla, Jacek

2001-01-01

The BaBar experiment at the Stanford Linear Accelerator Center (SLAC) is designed to perform a high precision investigation of the decays of the B-meson produced from electron-positron interactions. The experiment, started in May 1999, will generate approximately 300TB/year of data for 10 years. All of the data will reside in Objectivity databases accessible via the Advanced Multi-threaded Server (AMS). To date, over 70TB of data have been placed in Objectivity/DB, making it one of the largest databases in the world. Providing access to such a large quantity of data through a database server is a daunting task. A full-scale testbed environment had to be developed to tune various software parameters and a fundamental change had to occur in the AMS architecture to allow it to scale past several hundred terabytes of data. Additionally, several protocol extensions had to be implemented to provide practical access to large quantities of data. This paper will describe the design of the database and the changes that we needed to make in the AMS for scalability reasons and how the lessons we learned would be applicable to virtually any kind of database server seeking to operate in the Petabyte region

Creating Large Scale Database Servers

Energy Technology Data Exchange (ETDEWEB)

Becla, Jacek

2001-12-14

The BaBar experiment at the Stanford Linear Accelerator Center (SLAC) is designed to perform a high precision investigation of the decays of the B-meson produced from electron-positron interactions. The experiment, started in May 1999, will generate approximately 300TB/year of data for 10 years. All of the data will reside in Objectivity databases accessible via the Advanced Multi-threaded Server (AMS). To date, over 70TB of data have been placed in Objectivity/DB, making it one of the largest databases in the world. Providing access to such a large quantity of data through a database server is a daunting task. A full-scale testbed environment had to be developed to tune various software parameters and a fundamental change had to occur in the AMS architecture to allow it to scale past several hundred terabytes of data. Additionally, several protocol extensions had to be implemented to provide practical access to large quantities of data. This paper will describe the design of the database and the changes that we needed to make in the AMS for scalability reasons and how the lessons we learned would be applicable to virtually any kind of database server seeking to operate in the Petabyte region.

Personalized Pseudonyms for Servers in the Cloud

OpenAIRE

Xiao Qiuyu; Reiter Michael K.; Zhang Yinqian

2017-01-01

A considerable and growing fraction of servers, especially of web servers, is hosted in compute clouds. In this paper we opportunistically leverage this trend to improve privacy of clients from network attackers residing between the clients and the cloud: We design a system that can be deployed by the cloud operator to prevent a network adversary from determining which of the cloud’s tenant servers a client is accessing. The core innovation in our design is a PoPSiCl (pronounced “popsicle”), ...

Triple-server blind quantum computation using entanglement swapping

Science.gov (United States)

Li, Qin; Chan, Wai Hong; Wu, Chunhui; Wen, Zhonghua

2014-04-01

Blind quantum computation allows a client who does not have enough quantum resources or technologies to achieve quantum computation on a remote quantum server such that the client's input, output, and algorithm remain unknown to the server. Up to now, single- and double-server blind quantum computation have been considered. In this work, we propose a triple-server blind computation protocol where the client can delegate quantum computation to three quantum servers by the use of entanglement swapping. Furthermore, the three quantum servers can communicate with each other and the client is almost classical since one does not require any quantum computational power, quantum memory, and the ability to prepare any quantum states and only needs to be capable of getting access to quantum channels.

BioconductorBuntu: a Linux distribution that implements a web-based DNA microarray analysis server.

Science.gov (United States)

Geeleher, Paul; Morris, Dermot; Hinde, John P; Golden, Aaron

2009-06-01

BioconductorBuntu is a custom distribution of Ubuntu Linux that automatically installs a server-side microarray processing environment, providing a user-friendly web-based GUI to many of the tools developed by the Bioconductor Project, accessible locally or across a network. System installation is via booting off a CD image or by using a Debian package provided to upgrade an existing Ubuntu installation. In its current version, several microarray analysis pipelines are supported including oligonucleotide, dual-or single-dye experiments, including post-processing with Gene Set Enrichment Analysis. BioconductorBuntu is designed to be extensible, by server-side integration of further relevant Bioconductor modules as required, facilitated by its straightforward underlying Python-based infrastructure. BioconductorBuntu offers an ideal environment for the development of processing procedures to facilitate the analysis of next-generation sequencing datasets. BioconductorBuntu is available for download under a creative commons license along with additional documentation and a tutorial from (http://bioinf.nuigalway.ie).

mirVAFC: A Web Server for Prioritizations of Pathogenic Sequence Variants from Exome Sequencing Data via Classifications.

Science.gov (United States)

Li, Zhongshan; Liu, Zhenwei; Jiang, Yi; Chen, Denghui; Ran, Xia; Sun, Zhong Sheng; Wu, Jinyu

2017-01-01

Exome sequencing has been widely used to identify the genetic variants underlying human genetic disorders for clinical diagnoses, but the identification of pathogenic sequence variants among the huge amounts of benign ones is complicated and challenging. Here, we describe a new Web server named mirVAFC for pathogenic sequence variants prioritizations from clinical exome sequencing (CES) variant data of single individual or family. The mirVAFC is able to comprehensively annotate sequence variants, filter out most irrelevant variants using custom criteria, classify variants into different categories as for estimated pathogenicity, and lastly provide pathogenic variants prioritizations based on classifications and mutation effects. Case studies using different types of datasets for different diseases from publication and our in-house data have revealed that mirVAFC can efficiently identify the right pathogenic candidates as in original work in each case. Overall, the Web server mirVAFC is specifically developed for pathogenic sequence variant identifications from family-based CES variants using classification-based prioritizations. The mirVAFC Web server is freely accessible at https://www.wzgenomics.cn/mirVAFC/. © 2016 WILEY PERIODICALS, INC.

Server for experimental data from LHD

International Nuclear Information System (INIS)

Emoto, M.; Ohdachi, S.; Watanabe, K.; Sudo, S.; Nagayama, Y.

2006-01-01

In order to unify various types of data, the Kaiseki Server was developed. This server provides physical experimental data of large helical device (LHD) experiments. Many types of data acquisition systems currently exist in operation, and they produce files of various formats. Therefore, it has been difficult to analyze different types of acquisition data at the same time because the data of each system should be read in a particular manner. To facilitate the usage of this data by researchers, the authors have developed a new server system, which provides a unified data format and a unique data retrieval interface. Although the Kaiseki Server satisfied the initial demand, new requests arose from researchers, one of which was the remote usage of the server. The current system cannot be used remotely because of security issues. Another request was group ownership, i.e., users belonging to the same group should have equal access to data. To satisfy these demands, the authors modified the server. However, since other requests may arise in the future, the new system must be flexible so that it can satisfy future demands. Therefore, the authors decided to develop a new server using a three-tier structure

Analisis Perbandingan Unjuk Kerja Sistem Penyeimbang Beban Web Server dengan HAProxy dan Pound Links

Directory of Open Access Journals (Sweden)

Dite Ardian

2013-04-01

Full Text Available The development of internet technology has many organizations that expanded service website. Initially used single web server that is accessible to everyone through the Internet, but when the number of users that access the web server is very much the traffic load to the web server and the web server anyway. It is necessary for the optimization of web servers to cope with the overload received by the web server when traffic is high. Methodology of this final project research include the study of literature, system design, and testing of the system. Methods from the literature reference books related as well as from several sources the internet. The design of this thesis uses Haproxy and Pound Links as a load balancing web server. The end of this reaserch is testing the network system, where the system will be tested this stage so as to create a web server system that is reliable and safe. The result is a web server system that can be accessed by many user simultaneously rapidly as load balancing Haproxy and Pound Links system which is set up as front-end web server performance so as to create a web server that has performance and high availability.

Improved materials management through client/server computing

International Nuclear Information System (INIS)

Brooks, D.; Neilsen, E.; Reagan, R.; Simmons, D.

1992-01-01

This paper reports that materials management and procurement impacts every organization within an electric utility from power generation to customer service. An efficient material management and procurement system can help improve productivity and minimize operating costs. It is no longer sufficient to simply automate materials management using inventory control systems. Smart companies are building centralized data warehouses and use the client/server style of computing to provide real time data access. This paper describes how Alabama Power Company, Southern Company Services and Digital Equipment Corporation transformed two existing applications, a purchase order application within DEC's ALL-IN-1 environment and a materials management application within an IBM CICS environment, into a data warehouse - client/server application. An application server is used to overcome incompatibilities between computing environments and provide easy, real-time access to information residing in multi-vendor environments

RNAiFold: a web server for RNA inverse folding and molecular design.

Science.gov (United States)

Garcia-Martin, Juan Antonio; Clote, Peter; Dotu, Ivan

2013-07-01

Synthetic biology and nanotechnology are poised to make revolutionary contributions to the 21st century. In this article, we describe a new web server to support in silico RNA molecular design. Given an input target RNA secondary structure, together with optional constraints, such as requiring GC-content to lie within a certain range, requiring the number of strong (GC), weak (AU) and wobble (GU) base pairs to lie in a certain range, the RNAiFold web server determines one or more RNA sequences, whose minimum free-energy secondary structure is the target structure. RNAiFold provides access to two servers: RNA-CPdesign, which applies constraint programming, and RNA-LNSdesign, which applies the large neighborhood search heuristic; hence, it is suitable for larger input structures. Both servers can also solve the RNA inverse hybridization problem, i.e. given a representation of the desired hybridization structure, RNAiFold returns two sequences, whose minimum free-energy hybridization is the input target structure. The web server is publicly accessible at http://bioinformatics.bc.edu/clotelab/RNAiFold, which provides access to two specialized servers: RNA-CPdesign and RNA-LNSdesign. Source code for the underlying algorithms, implemented in COMET and supported on linux, can be downloaded at the server website.

Datasets will not be made accessible to the public due to the fact that they include household level data with PII.

Data.gov (United States)

U.S. Environmental Protection Agency — Datasets will not be made accessible to the public due to the fact that they include household level data with PII. This dataset is not publicly accessible because:...

The SAMGrid database server component: its upgraded infrastructure and future development path

International Nuclear Information System (INIS)

Loebel-Carpenter, L.; White, S.; Baranovski, A.; Garzoglio, G.; Herber, R.; Illingworth, R.; Kennedy, R.; Kreymer, A.; Kumar, A.; Lueking, L.; Lyon, A.; Merritt, W.; Terekhov, I.; Trumbo, J.; Veseli, S.; Burgon-Lyon, M.; St Denis, R.; Belforte, S.; Kerzel, U.; Bartsch, V.; Leslie, M.

2004-01-01

The SAMGrid Database Server encapsulates several important services, such as accessing file metadata and replica catalog, keeping track of the processing information, as well as providing the runtime support for SAMGrid station services. Recent deployment of the SAMGrid system for CDF has resulted in unification of the database schema used by CDF and D0, and the complexity of changes required for the unified metadata catalog has warranted a complete redesign of the DB Server. We describe here the architecture and features of the new server. In particular, we discuss the new CORBA infrastructure that utilizes python wrapper classes around IDL structs and exceptions. Such infrastructure allows us to use the same code on both server and client sides, which in turn results in significantly improved code maintainability and easier development. We also discuss future integration of the new server with an SBIR II project which is directed toward allowing the DB Server to access distributed databases, implemented in different DB systems and possibly using different schema

Design of Accelerator Online Simulator Server Using Structured Data

International Nuclear Information System (INIS)

Shen, Guobao

2012-01-01

Model based control plays an important role for a modern accelerator during beam commissioning, beam study, and even daily operation. With a realistic model, beam behaviour can be predicted and therefore effectively controlled. The approach used by most current high level application environments is to use a built-in simulation engine and feed a realistic model into that simulation engine. Instead of this traditional monolithic structure, a new approach using a client-server architecture is under development. An on-line simulator server is accessed via network accessible structured data. With this approach, a user can easily access multiple simulation codes. This paper describes the design, implementation, and current status of PVData, which defines the structured data, and PVAccess, which provides network access to the structured data.

Earth science big data at users' fingertips: the EarthServer Science Gateway Mobile

Science.gov (United States)

Barbera, Roberto; Bruno, Riccardo; Calanducci, Antonio; Fargetta, Marco; Pappalardo, Marco; Rundo, Francesco

2014-05-01

The EarthServer project (www.earthserver.eu), funded by the European Commission under its Seventh Framework Program, aims at establishing open access and ad-hoc analytics on extreme-size Earth Science data, based on and extending leading-edge Array Database technology. The core idea is to use database query languages as client/server interface to achieve barrier-free "mix & match" access to multi-source, any-size, multi-dimensional space-time data -- in short: "Big Earth Data Analytics" - based on the open standards of the Open Geospatial Consortium Web Coverage Processing Service (OGC WCPS) and the W3C XQuery. EarthServer combines both, thereby achieving a tight data/metadata integration. Further, the rasdaman Array Database System (www.rasdaman.com) is extended with further space-time coverage data types. On server side, highly effective optimizations - such as parallel and distributed query processing - ensure scalability to Exabyte volumes. In this contribution we will report on the EarthServer Science Gateway Mobile, an app for both iOS and Android-based devices that allows users to seamlessly access some of the EarthServer applications using SAML-based federated authentication and fine-grained authorisation mechanisms.

Characteristics and Energy Use of Volume Servers in the United States

Energy Technology Data Exchange (ETDEWEB)

Fuchs, H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Shehabi, A. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Ganeshalingam, M. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Desroches, L. -B. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Lim, B. [Fraunhofer Center for Sustainable Energy Systems, Boston, MA (United States); Roth, K. [Fraunhofer Center for Sustainable Energy Systems, Boston, MA (United States); Tsao, A. [Navigant Consulting Inc., Chicago, IL (United States)

2017-11-01

Servers’ field energy use remains poorly understood, given heterogeneous computing loads, configurable hardware and software, and operation over a wide range of management practices. This paper explores various characteristics of 1- and 2-socket volume servers that affect energy consumption, and quantifies the difference in power demand between higher-performing SPEC and ENERGY STAR servers and our best understanding of a typical server operating today. We first establish general characteristics of the U.S. installed base of volume servers from existing IDC data and the literature, before presenting information on server hardware configurations from data collection events at a major online retail website. We then compare cumulative distribution functions of server idle power across three separate datasets and explain the differences between them via examination of the hardware characteristics to which power draw is most sensitive. We find that idle server power demand is significantly higher than ENERGY STAR benchmarks and the industry-released energy use documented in SPEC, and that SPEC server configurations—and likely the associated power-scaling trends—are atypical of volume servers. Next, we examine recent trends in server power draw among high-performing servers across their full load range to consider how representative these trends are of all volume servers before inputting weighted average idle power load values into a recently published model of national server energy use. Finally, we present results from two surveys of IT managers (n=216) and IT vendors (n=178) that illustrate the prevalence of more-efficient equipment and operational practices in server rooms and closets; these findings highlight opportunities to improve the energy efficiency of the U.S. server stock.

R3D Align web server for global nucleotide to nucleotide alignments of RNA 3D structures.

Science.gov (United States)

Rahrig, Ryan R; Petrov, Anton I; Leontis, Neocles B; Zirbel, Craig L

2013-07-01

The R3D Align web server provides online access to 'RNA 3D Align' (R3D Align), a method for producing accurate nucleotide-level structural alignments of RNA 3D structures. The web server provides a streamlined and intuitive interface, input data validation and output that is more extensive and easier to read and interpret than related servers. The R3D Align web server offers a unique Gallery of Featured Alignments, providing immediate access to pre-computed alignments of large RNA 3D structures, including all ribosomal RNAs, as well as guidance on effective use of the server and interpretation of the output. By accessing the non-redundant lists of RNA 3D structures provided by the Bowling Green State University RNA group, R3D Align connects users to structure files in the same equivalence class and the best-modeled representative structure from each group. The R3D Align web server is freely accessible at http://rna.bgsu.edu/r3dalign/.

The Difference Between Using Proxy Server and VPN

Directory of Open Access Journals (Sweden)

David Dwiputra Kurniadi

2015-11-01

For example, looking for software, game through internet. But sometimes, there are some websites that cannot be opened as they have Internet Positive notificatio. To solve that problem, hacker found the solution by creating Proxy Server or VPN. In this time internet is very modern and very easy to access and there are a lot of Proxy Server and VPN that can be easly used.

The MetabolomeExpress Project: enabling web-based processing, analysis and transparent dissemination of GC/MS metabolomics datasets

Directory of Open Access Journals (Sweden)

Carroll Adam J

2010-07-01

Full Text Available Abstract Background Standardization of analytical approaches and reporting methods via community-wide collaboration can work synergistically with web-tool development to result in rapid community-driven expansion of online data repositories suitable for data mining and meta-analysis. In metabolomics, the inter-laboratory reproducibility of gas-chromatography/mass-spectrometry (GC/MS makes it an obvious target for such development. While a number of web-tools offer access to datasets and/or tools for raw data processing and statistical analysis, none of these systems are currently set up to act as a public repository by easily accepting, processing and presenting publicly submitted GC/MS metabolomics datasets for public re-analysis. Description Here, we present MetabolomeExpress, a new File Transfer Protocol (FTP server and web-tool for the online storage, processing, visualisation and statistical re-analysis of publicly submitted GC/MS metabolomics datasets. Users may search a quality-controlled database of metabolite response statistics from publicly submitted datasets by a number of parameters (eg. metabolite, species, organ/biofluid etc.. Users may also perform meta-analysis comparisons of multiple independent experiments or re-analyse public primary datasets via user-friendly tools for t-test, principal components analysis, hierarchical cluster analysis and correlation analysis. They may interact with chromatograms, mass spectra and peak detection results via an integrated raw data viewer. Researchers who register for a free account may upload (via FTP their own data to the server for online processing via a novel raw data processing pipeline. Conclusions MetabolomeExpress https://www.metabolome-express.org provides a new opportunity for the general metabolomics community to transparently present online the raw and processed GC/MS data underlying their metabolomics publications. Transparent sharing of these data will allow researchers to

Utilizing the Antarctic Master Directory to find orphan datasets

Science.gov (United States)

Bonczkowski, J.; Carbotte, S. M.; Arko, R. A.; Grebas, S. K.

2011-12-01

While most Antarctic data are housed at an established disciplinary-specific data repository, there are data types for which no suitable repository exists. In some cases, these "orphan" data, without an appropriate national archive, are served from local servers by the principal investigators who produced the data. There are many pitfalls with data served privately, including the frequent lack of adequate documentation to ensure the data can be understood by others for re-use and the impermanence of personal web sites. For example, if an investigator leaves an institution and the data moves, the link published is no longer accessible. To ensure continued availability of data, submission to long-term national data repositories is needed. As stated in the National Science Foundation Office of Polar Programs (NSF/OPP) Guidelines and Award Conditions for Scientific Data, investigators are obligated to submit their data for curation and long-term preservation; this includes the registration of a dataset description into the Antarctic Master Directory (AMD), http://gcmd.nasa.gov/Data/portals/amd/. The AMD is a Web-based, searchable directory of thousands of dataset descriptions, known as DIF records, submitted by scientists from over 20 countries. It serves as a node of the International Directory Network/Global Change Master Directory (IDN/GCMD). The US Antarctic Program Data Coordination Center (USAP-DCC), http://www.usap-data.org/, funded through NSF/OPP, was established in 2007 to help streamline the process of data submission and DIF record creation. When data does not quite fit within any existing disciplinary repository, it can be registered within the USAP-DCC as the fallback data repository. Within the scope of the USAP-DCC we undertook the challenge of discovering and "rescuing" orphan datasets currently registered within the AMD. In order to find which DIF records led to data served privately, all records relating to US data within the AMD were parsed. After

Data-driven decision support for radiologists: re-using the National Lung Screening Trial dataset for pulmonary nodule management.

Science.gov (United States)

Morrison, James J; Hostetter, Jason; Wang, Kenneth; Siegel, Eliot L

2015-02-01

Real-time mining of large research trial datasets enables development of case-based clinical decision support tools. Several applicable research datasets exist including the National Lung Screening Trial (NLST), a dataset unparalleled in size and scope for studying population-based lung cancer screening. Using these data, a clinical decision support tool was developed which matches patient demographics and lung nodule characteristics to a cohort of similar patients. The NLST dataset was converted into Structured Query Language (SQL) tables hosted on a web server, and a web-based JavaScript application was developed which performs real-time queries. JavaScript is used for both the server-side and client-side language, allowing for rapid development of a robust client interface and server-side data layer. Real-time data mining of user-specified patient cohorts achieved a rapid return of cohort cancer statistics and lung nodule distribution information. This system demonstrates the potential of individualized real-time data mining using large high-quality clinical trial datasets to drive evidence-based clinical decision-making.

Cybersecurity, massive data processing, community interaction, and other developments at WWW-based computational X-ray Server

Science.gov (United States)

Stepanov, Sergey

2013-03-01

X-Ray Server (x-server.gmca.aps.anl.gov) is a WWW-based computational server for modeling of X-ray diffraction, reflection and scattering data. The modeling software operates directly on the server and can be accessed remotely either from web browsers or from user software. In the later case the server can be deployed as a software library or a data fitting engine. As the server recently surpassed the milestones of 15 years online and 1.5 million calculations, it accumulated a number of technical solutions that are discussed in this paper. The developed approaches to detecting physical model limits and user calculations failures, solutions to spam and firewall problems, ways to involve the community in replenishing databases and methods to teach users automated access to the server programs may be helpful for X-ray researchers interested in using the server or sharing their own software online.

Cybersecurity, massive data processing, community interaction, and other developments at WWW-based computational X-ray Server

International Nuclear Information System (INIS)

Stepanov, Sergey

2013-01-01

X-Ray Server (x-server.gmca.aps.anl.gov) is a WWW-based computational server for modeling of X-ray diffraction, reflection and scattering data. The modeling software operates directly on the server and can be accessed remotely either from web browsers or from user software. In the later case the server can be deployed as a software library or a data fitting engine. As the server recently surpassed the milestones of 15 years online and 1.5 million calculations, it accumulated a number of technical solutions that are discussed in this paper. The developed approaches to detecting physical model limits and user calculations failures, solutions to spam and firewall problems, ways to involve the community in replenishing databases and methods to teach users automated access to the server programs may be helpful for X-ray researchers interested in using the server or sharing their own software online.

Enforcing Resource Sharing Agreements Among Distributed Server Clusters

National Research Council Canada - National Science Library

Zhao, Tao; Karamcheti, Vijay

2001-01-01

Future scalable, high throughput, and high performance applications are likely to execute on platforms constructed by clustering multiple autonomous distributed servers, with resource access governed...

Distributed PACS using distributed file system with hierarchical meta data servers.

Science.gov (United States)

Hiroyasu, Tomoyuki; Minamitani, Yoshiyuki; Miki, Mitsunori; Yokouchi, Hisatake; Yoshimi, Masato

2012-01-01

In this research, we propose a new distributed PACS (Picture Archiving and Communication Systems) which is available to integrate several PACSs that exist in each medical institution. The conventional PACS controls DICOM file into one data-base. On the other hand, in the proposed system, DICOM file is separated into meta data and image data and those are stored individually. Using this mechanism, since file is not always accessed the entire data, some operations such as finding files, changing titles, and so on can be performed in high-speed. At the same time, as distributed file system is utilized, accessing image files can also achieve high-speed access and high fault tolerant. The introduced system has a more significant point. That is the simplicity to integrate several PACSs. In the proposed system, only the meta data servers are integrated and integrated system can be constructed. This system also has the scalability of file access with along to the number of file numbers and file sizes. On the other hand, because meta-data server is integrated, the meta data server is the weakness of this system. To solve this defect, hieratical meta data servers are introduced. Because of this mechanism, not only fault--tolerant ability is increased but scalability of file access is also increased. To discuss the proposed system, the prototype system using Gfarm was implemented. For evaluating the implemented system, file search operating time of Gfarm and NFS were compared.

CovalentDock Cloud: a web server for automated covalent docking.

Science.gov (United States)

Ouyang, Xuchang; Zhou, Shuo; Ge, Zemei; Li, Runtao; Kwoh, Chee Keong

2013-07-01

Covalent binding is an important mechanism for many drugs to gain its function. We developed a computational algorithm to model this chemical event and extended it to a web server, the CovalentDock Cloud, to make it accessible directly online without any local installation and configuration. It provides a simple yet user-friendly web interface to perform covalent docking experiments and analysis online. The web server accepts the structures of both the ligand and the receptor uploaded by the user or retrieved from online databases with valid access id. It identifies the potential covalent binding patterns, carries out the covalent docking experiments and provides visualization of the result for user analysis. This web server is free and open to all users at http://docking.sce.ntu.edu.sg/.

Earth System Model Development and Analysis using FRE-Curator and Live Access Servers: On-demand analysis of climate model output with data provenance.

Science.gov (United States)

Radhakrishnan, A.; Balaji, V.; Schweitzer, R.; Nikonov, S.; O'Brien, K.; Vahlenkamp, H.; Burger, E. F.

2016-12-01

There are distinct phases in the development cycle of an Earth system model. During the model development phase, scientists make changes to code and parameters and require rapid access to results for evaluation. During the production phase, scientists may make an ensemble of runs with different settings, and produce large quantities of output, that must be further analyzed and quality controlled for scientific papers and submission to international projects such as the Climate Model Intercomparison Project (CMIP). During this phase, provenance is a key concern:being able to track back from outputs to inputs. We will discuss one of the paths taken at GFDL in delivering tools across this lifecycle, offering on-demand analysis of data by integrating the use of GFDL's in-house FRE-Curator, Unidata's THREDDS and NOAA PMEL's Live Access Servers (LAS).Experience over this lifecycle suggests that a major difficulty in developing analysis capabilities is only partially the scientific content, but often devoted to answering the questions "where is the data?" and "how do I get to it?". "FRE-Curator" is the name of a database-centric paradigm used at NOAA GFDL to ingest information about the model runs into an RDBMS (Curator database). The components of FRE-Curator are integrated into Flexible Runtime Environment workflow and can be invoked during climate model simulation. The front end to FRE-Curator, known as the Model Development Database Interface (MDBI) provides an in-house web-based access to GFDL experiments: metadata, analysis output and more. In order to provide on-demand visualization, MDBI uses Live Access Servers which is a highly configurable web server designed to provide flexible access to geo-referenced scientific data, that makes use of OPeNDAP. Model output saved in GFDL's tape archive, the size of the database and experiments, continuous model development initiatives with more dynamic configurations add complexity and challenges in providing an on

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update.

Science.gov (United States)

Afgan, Enis; Baker, Dannon; Batut, Bérénice; van den Beek, Marius; Bouvier, Dave; Cech, Martin; Chilton, John; Clements, Dave; Coraor, Nate; Grüning, Björn A; Guerler, Aysam; Hillman-Jackson, Jennifer; Hiltemann, Saskia; Jalili, Vahid; Rasche, Helena; Soranzo, Nicola; Goecks, Jeremy; Taylor, James; Nekrutenko, Anton; Blankenberg, Daniel

2018-05-22

Galaxy (homepage: https://galaxyproject.org, main public server: https://usegalaxy.org) is a web-based scientific analysis platform used by tens of thousands of scientists across the world to analyze large biomedical datasets such as those found in genomics, proteomics, metabolomics and imaging. Started in 2005, Galaxy continues to focus on three key challenges of data-driven biomedical science: making analyses accessible to all researchers, ensuring analyses are completely reproducible, and making it simple to communicate analyses so that they can be reused and extended. During the last two years, the Galaxy team and the open-source community around Galaxy have made substantial improvements to Galaxy's core framework, user interface, tools, and training materials. Framework and user interface improvements now enable Galaxy to be used for analyzing tens of thousands of datasets, and >5500 tools are now available from the Galaxy ToolShed. The Galaxy community has led an effort to create numerous high-quality tutorials focused on common types of genomic analyses. The Galaxy developer and user communities continue to grow and be integral to Galaxy's development. The number of Galaxy public servers, developers contributing to the Galaxy framework and its tools, and users of the main Galaxy server have all increased substantially.

Analisis Perbandingan Load Balancing Web Server Tunggal Dengan Web Server Cluster Menggunakan Linux Virtual Server

OpenAIRE

Lukitasari, Desy; Oklilas, Ahmad Fali

2010-01-01

Virtual server adalah server yang mempunyai skalabilitas dan ketersedian yang tinggi yang dibangun diatas sebuah cluster dari beberapa real server. Real server dan load balancer akan saling terkoneksi baik dalam jaringan lokal kecepatan tinggi atau yang terpisah secara geografis. Load balancer dapat mengirim permintaan-permintaan ke server yang berbeda dan membuat paralel service dari sebuah cluster pada sebuah alamat IP tunggal dan meminta pengiriman dapat menggunakan teknologi IP load...

Extensible Synthetic File Servers? or: Structuring the Glue between Tester and System Under Test

NARCIS (Netherlands)

Belinfante, Axel; Mullender, Sape J.; Collyer, G.

2007-01-01

We discuss a few simple scenarios of how we can design and develop a compositional synthetic ��?le server that gives access to external processes – in particular, in the context of testing, gives access to the system under test – such that certain parts of said synthethic ��?le server can be

Improvements to the National Transport Code Collaboration Data Server

Science.gov (United States)

Alexander, David A.

2001-10-01

The data server of the National Transport Code Colaboration Project provides a universal network interface to interpolated or raw transport data accessible by a universal set of names. Data can be acquired from a local copy of the Iternational Multi-Tokamak (ITER) profile database as well as from TRANSP trees of MDS Plus data systems on the net. Data is provided to the user's network client via a CORBA interface, thus providing stateful data server instances, which have the advantage of remembering the desired interpolation, data set, etc. This paper will review the status and discuss the recent improvements made to the data server, such as the modularization of the data server and the addition of hdf5 and MDS Plus data file writing capability.

Bringing it All Together: NODC's Geoportal Server as an Integration Tool for Interoperable Data Services

Science.gov (United States)

Casey, K. S.; Li, Y.

2011-12-01

The US National Oceanographic Data Center (NODC) has implemented numerous interoperable data technologies in recent years to enhance the discovery, understanding, and use of the vast quantities of data in the NODC archives. These services include OPeNDAP's Hyrax server, Unidata's THREDDS Data Server (TDS), NOAA's Live Access Server (LAS), and most recently the ESRI ArcGIS Server. Combined, these technologies enable NODC to provide access to its data holdings and products through most of the commonly-used standardized web services like the Data Access Protocol (DAP) and the Open Geospatial Consortium suite of services such as the Web Mapping Service (WMS) and Web Coverage Service (WCS). Despite the strong demand for and use of these services, the acronym-rich environment of services can also result in confusion for producers of data to the NODC archives, for consumers of data from the NODC archives, and for the data stewards at the archives as well. The situation is further complicated by the fact that NODC also maintains some ad hoc services like WODselect, and that not all services can be applied to all of the tens of thousands of collections in the NODC archive; where once every data set was available only through FTP and HTTP servers, now many are also available from the LAS, TDS, Hyrax, and ArcGIS Server. To bring order and clarity to this potentially confusing collection of services, NODC deployed the Geoportal Server into its Archive Management System as an integrating technology that brings together its various data access, visualization, and discovery services as well as its overall metadata management workflows. While providing an enhanced web-based interface for more integrated human-to-machine discovery and access, the deployment also enables NODC for the first time to support a robust set of machine-to-machine discovery services such as the Catalog Service for the Web (CS/W), OpenSearch, and Search and Retrieval via URL (SRU) . This approach allows NODC

Client/server models for transparent, distributed computational resources

International Nuclear Information System (INIS)

Hammer, K.E.; Gilman, T.L.

1991-01-01

Client/server models are proposed to address issues of shared resources in a distributed, heterogeneous UNIX environment. Recent development of automated Remote Procedure Call (RPC) interface generator has simplified the development of client/server models. Previously, implementation of the models was only possible at the UNIX socket level. An overview of RPCs and the interface generator will be presented and will include a discussion of generation and installation of remote services, the RPC paradigm, and the three levels of RPC programming. Two applications, the Nuclear Plant Analyzer (NPA) and a fluids simulation using molecular modelling, will be presented to demonstrate how client/server models using RPCs and External Data Representations (XDR) have been used production/computation situations. The NPA incorporates a client/server interface for transferring/translation of TRAC or RELAP results from the UNICOS Cray to a UNIX workstation. The fluids simulation program utilizes the client/server model to access the Cray via a single function allowing it to become a shared co-processor to the workstation application. 5 refs., 6 figs

WebMGA: a customizable web server for fast metagenomic sequence analysis.

Science.gov (United States)

Wu, Sitao; Zhu, Zhengwei; Fu, Liming; Niu, Beifang; Li, Weizhong

2011-09-07

The new field of metagenomics studies microorganism communities by culture-independent sequencing. With the advances in next-generation sequencing techniques, researchers are facing tremendous challenges in metagenomic data analysis due to huge quantity and high complexity of sequence data. Analyzing large datasets is extremely time-consuming; also metagenomic annotation involves a wide range of computational tools, which are difficult to be installed and maintained by common users. The tools provided by the few available web servers are also limited and have various constraints such as login requirement, long waiting time, inability to configure pipelines etc. We developed WebMGA, a customizable web server for fast metagenomic analysis. WebMGA includes over 20 commonly used tools such as ORF calling, sequence clustering, quality control of raw reads, removal of sequencing artifacts and contaminations, taxonomic analysis, functional annotation etc. WebMGA provides users with rapid metagenomic data analysis using fast and effective tools, which have been implemented to run in parallel on our local computer cluster. Users can access WebMGA through web browsers or programming scripts to perform individual analysis or to configure and run customized pipelines. WebMGA is freely available at http://weizhongli-lab.org/metagenomic-analysis. WebMGA offers to researchers many fast and unique tools and great flexibility for complex metagenomic data analysis.

WebMGA: a customizable web server for fast metagenomic sequence analysis

Directory of Open Access Journals (Sweden)

Niu Beifang

2011-09-01

Full Text Available Abstract Background The new field of metagenomics studies microorganism communities by culture-independent sequencing. With the advances in next-generation sequencing techniques, researchers are facing tremendous challenges in metagenomic data analysis due to huge quantity and high complexity of sequence data. Analyzing large datasets is extremely time-consuming; also metagenomic annotation involves a wide range of computational tools, which are difficult to be installed and maintained by common users. The tools provided by the few available web servers are also limited and have various constraints such as login requirement, long waiting time, inability to configure pipelines etc. Results We developed WebMGA, a customizable web server for fast metagenomic analysis. WebMGA includes over 20 commonly used tools such as ORF calling, sequence clustering, quality control of raw reads, removal of sequencing artifacts and contaminations, taxonomic analysis, functional annotation etc. WebMGA provides users with rapid metagenomic data analysis using fast and effective tools, which have been implemented to run in parallel on our local computer cluster. Users can access WebMGA through web browsers or programming scripts to perform individual analysis or to configure and run customized pipelines. WebMGA is freely available at http://weizhongli-lab.org/metagenomic-analysis. Conclusions WebMGA offers to researchers many fast and unique tools and great flexibility for complex metagenomic data analysis.

RBscore&NBench: a high-level web server for nucleic acid binding residues prediction with a large-scale benchmarking database.

Science.gov (United States)

Miao, Zhichao; Westhof, Eric

2016-07-08

RBscore&NBench combines a web server, RBscore and a database, NBench. RBscore predicts RNA-/DNA-binding residues in proteins and visualizes the prediction scores and features on protein structures. The scoring scheme of RBscore directly links feature values to nucleic acid binding probabilities and illustrates the nucleic acid binding energy funnel on the protein surface. To avoid dataset, binding site definition and assessment metric biases, we compared RBscore with 18 web servers and 3 stand-alone programs on 41 datasets, which demonstrated the high and stable accuracy of RBscore. A comprehensive comparison led us to develop a benchmark database named NBench. The web server is available on: http://ahsoka.u-strasbg.fr/rbscorenbench/. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

RaptorX-Property: a web server for protein structure property prediction.

Science.gov (United States)

Wang, Sheng; Li, Wei; Liu, Shiwang; Xu, Jinbo

2016-07-08

RaptorX Property (http://raptorx2.uchicago.edu/StructurePropertyPred/predict/) is a web server predicting structure property of a protein sequence without using any templates. It outperforms other servers, especially for proteins without close homologs in PDB or with very sparse sequence profile (i.e. carries little evolutionary information). This server employs a powerful in-house deep learning model DeepCNF (Deep Convolutional Neural Fields) to predict secondary structure (SS), solvent accessibility (ACC) and disorder regions (DISO). DeepCNF not only models complex sequence-structure relationship by a deep hierarchical architecture, but also interdependency between adjacent property labels. Our experimental results show that, tested on CASP10, CASP11 and the other benchmarks, this server can obtain ∼84% Q3 accuracy for 3-state SS, ∼72% Q8 accuracy for 8-state SS, ∼66% Q3 accuracy for 3-state solvent accessibility, and ∼0.89 area under the ROC curve (AUC) for disorder prediction. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

TogoDoc server/client system: smart recommendation and efficient management of life science literature.

Directory of Open Access Journals (Sweden)

Wataru Iwasaki

Full Text Available In this paper, we describe a server/client literature management system specialized for the life science domain, the TogoDoc system (Togo, pronounced Toe-Go, is a romanization of a Japanese word for integration. The server and the client program cooperate closely over the Internet to provide life scientists with an effective literature recommendation service and efficient literature management. The content-based and personalized literature recommendation helps researchers to isolate interesting papers from the "tsunami" of literature, in which, on average, more than one biomedical paper is added to MEDLINE every minute. Because researchers these days need to cover updates of much wider topics to generate hypotheses using massive datasets obtained from public databases or omics experiments, the importance of having an effective literature recommendation service is rising. The automatic recommendation is based on the content of personal literature libraries of electronic PDF papers. The client program automatically analyzes these files, which are sometimes deeply buried in storage disks of researchers' personal computers. Just saving PDF papers to the designated folders makes the client program automatically analyze and retrieve metadata, rename file names, synchronize the data to the server, and receive the recommendation lists of newly published papers, thus accomplishing effortless literature management. In addition, the tag suggestion and associative search functions are provided for easy classification of and access to past papers (researchers who read many papers sometimes only vaguely remember or completely forget what they read in the past. The TogoDoc system is available for both Windows and Mac OS X and is free. The TogoDoc Client software is available at http://tdc.cb.k.u-tokyo.ac.jp/, and the TogoDoc server is available at https://docman.dbcls.jp/pubmed_recom.

TogoDoc server/client system: smart recommendation and efficient management of life science literature.

Science.gov (United States)

Iwasaki, Wataru; Yamamoto, Yasunori; Takagi, Toshihisa

2010-12-13

In this paper, we describe a server/client literature management system specialized for the life science domain, the TogoDoc system (Togo, pronounced Toe-Go, is a romanization of a Japanese word for integration). The server and the client program cooperate closely over the Internet to provide life scientists with an effective literature recommendation service and efficient literature management. The content-based and personalized literature recommendation helps researchers to isolate interesting papers from the "tsunami" of literature, in which, on average, more than one biomedical paper is added to MEDLINE every minute. Because researchers these days need to cover updates of much wider topics to generate hypotheses using massive datasets obtained from public databases or omics experiments, the importance of having an effective literature recommendation service is rising. The automatic recommendation is based on the content of personal literature libraries of electronic PDF papers. The client program automatically analyzes these files, which are sometimes deeply buried in storage disks of researchers' personal computers. Just saving PDF papers to the designated folders makes the client program automatically analyze and retrieve metadata, rename file names, synchronize the data to the server, and receive the recommendation lists of newly published papers, thus accomplishing effortless literature management. In addition, the tag suggestion and associative search functions are provided for easy classification of and access to past papers (researchers who read many papers sometimes only vaguely remember or completely forget what they read in the past). The TogoDoc system is available for both Windows and Mac OS X and is free. The TogoDoc Client software is available at http://tdc.cb.k.u-tokyo.ac.jp/, and the TogoDoc server is available at https://docman.dbcls.jp/pubmed_recom.

The FOLDALIGN web server for pairwise structural RNA alignment and mutual motif search

DEFF Research Database (Denmark)

Havgaard, Jakob Hull; Lyngsø, Rune B.; Gorodkin, Jan

2005-01-01

FOLDALIGN is a Sankoff-based algorithm for making structural alignments of RNA sequences. Here, we present a web server for making pairwise alignments between two RNA sequences, using the recently updated version of FOLDALIGN. The server can be used to scan two sequences for a common structural RNA...... motif of limited size, or the entire sequences can be aligned locally or globally. The web server offers a graphical interface, which makes it simple to make alignments and manually browse the results. the web server can be accessed at http://foldalign.kvl.dk...

Distributed metadata servers for cluster file systems using shared low latency persistent key-value metadata store

Science.gov (United States)

Bent, John M.; Faibish, Sorin; Pedone, Jr., James M.; Tzelnic, Percy; Ting, Dennis P. J.; Ionkov, Latchesar A.; Grider, Gary

2017-12-26

A cluster file system is provided having a plurality of distributed metadata servers with shared access to one or more shared low latency persistent key-value metadata stores. A metadata server comprises an abstract storage interface comprising a software interface module that communicates with at least one shared persistent key-value metadata store providing a key-value interface for persistent storage of key-value metadata. The software interface module provides the key-value metadata to the at least one shared persistent key-value metadata store in a key-value format. The shared persistent key-value metadata store is accessed by a plurality of metadata servers. A metadata request can be processed by a given metadata server independently of other metadata servers in the cluster file system. A distributed metadata storage environment is also disclosed that comprises a plurality of metadata servers having an abstract storage interface to at least one shared persistent key-value metadata store.

Automated grading of homework assignments and tests in introductory and intermediate statistics courses using active server pages.

Science.gov (United States)

Stockburger, D W

1999-05-01

Active server pages permit a software developer to customize the Web experience for users by inserting server-side script and database access into Web pages. This paper describes applications of these techniques and provides a primer on the use of these methods. Applications include a system that generates and grades individualized homework assignments and tests for statistics students. The student accesses the system as a Web page, prints out the assignment, does the assignment, and enters the answers on the Web page. The server, running on NT Server 4.0, grades the assignment, updates the grade book (on a database), and returns the answer key to the student.

KFC Server: interactive forecasting of protein interaction hot spots.

Science.gov (United States)

Darnell, Steven J; LeGault, Laura; Mitchell, Julie C

2008-07-01

The KFC Server is a web-based implementation of the KFC (Knowledge-based FADE and Contacts) model-a machine learning approach for the prediction of binding hot spots, or the subset of residues that account for most of a protein interface's; binding free energy. The server facilitates the automated analysis of a user submitted protein-protein or protein-DNA interface and the visualization of its hot spot predictions. For each residue in the interface, the KFC Server characterizes its local structural environment, compares that environment to the environments of experimentally determined hot spots and predicts if the interface residue is a hot spot. After the computational analysis, the user can visualize the results using an interactive job viewer able to quickly highlight predicted hot spots and surrounding structural features within the protein structure. The KFC Server is accessible at http://kfc.mitchell-lab.org.

Mfold web server for nucleic acid folding and hybridization prediction.

Science.gov (United States)

Zuker, Michael

2003-07-01

The abbreviated name, 'mfold web server', describes a number of closely related software applications available on the World Wide Web (WWW) for the prediction of the secondary structure of single stranded nucleic acids. The objective of this web server is to provide easy access to RNA and DNA folding and hybridization software to the scientific community at large. By making use of universally available web GUIs (Graphical User Interfaces), the server circumvents the problem of portability of this software. Detailed output, in the form of structure plots with or without reliability information, single strand frequency plots and 'energy dot plots', are available for the folding of single sequences. A variety of 'bulk' servers give less information, but in a shorter time and for up to hundreds of sequences at once. The portal for the mfold web server is http://www.bioinfo.rpi.edu/applications/mfold. This URL will be referred to as 'MFOLDROOT'.

UPGRADE OF THE CENTRAL WEB SERVERS

CERN Multimedia

WEB Services

2000-01-01

During the weekend of the 25-26 March, the infrastructure of the CERN central web servers will undergo a major upgrade.As a result, the web services hosted by the central servers (that is, the services the address of which starts with www.cern.ch) will be unavailable Friday 24th, from 17:30 to 18:30, and may suffer from short interruptions until 20:00. This includes access to the CERN top-level page as well as the services referenced by this page (such as access to the scientific program and events information, or training, recruitment, housing services).After the upgrade, the change will be transparent to the users. Expert readers may however notice that when they connect to a web page starting with www.cern.ch this address is slightly changed when the page is actually displayed on their screen (e.g. www.cern.ch/Press will be changed to Press.web.cern.ch/Press). They should not worry: this behaviour, necessary for technical reasons, is normal.web.services@cern.chTel 74989

HDF-EOS Web Server

Science.gov (United States)

Ullman, Richard; Bane, Bob; Yang, Jingli

2008-01-01

A shell script has been written as a means of automatically making HDF-EOS-formatted data sets available via the World Wide Web. ("HDF-EOS" and variants thereof are defined in the first of the two immediately preceding articles.) The shell script chains together some software tools developed by the Data Usability Group at Goddard Space Flight Center to perform the following actions: Extract metadata in Object Definition Language (ODL) from an HDF-EOS file, Convert the metadata from ODL to Extensible Markup Language (XML), Reformat the XML metadata into human-readable Hypertext Markup Language (HTML), Publish the HTML metadata and the original HDF-EOS file to a Web server and an Open-source Project for a Network Data Access Protocol (OPeN-DAP) server computer, and Reformat the XML metadata and submit the resulting file to the EOS Clearinghouse, which is a Web-based metadata clearinghouse that facilitates searching for, and exchange of, Earth-Science data.

Detection of attack-targeted scans from the Apache HTTP Server access logs

Directory of Open Access Journals (Sweden)

Merve Baş Seyyar

2018-01-01

Full Text Available A web application could be visited for different purposes. It is possible for a web site to be visited by a regular user as a normal (natural visit, to be viewed by crawlers, bots, spiders, etc. for indexing purposes, lastly to be exploratory scanned by malicious users prior to an attack. An attack targeted web scan can be viewed as a phase of a potential attack and can lead to more attack detection as compared to traditional detection methods. In this work, we propose a method to detect attack-oriented scans and to distinguish them from other types of visits. In this context, we use access log files of Apache (or ISS web servers and try to determine attack situations through examination of the past data. In addition to web scan detections, we insert a rule set to detect SQL Injection and XSS attacks. Our approach has been applied on sample data sets and results have been analyzed in terms of performance measures to compare our method and other commonly used detection techniques. Furthermore, various tests have been made on log samples from real systems. Lastly, several suggestions about further development have been also discussed.

Implementing an SMB2 Server in the Vortex Operating System

OpenAIRE

Sandengen, Vegard

2015-01-01

With the advent of computer networks, the ability for sharing and accessing files across the network between multiple workstations and remote servers was sought after. In the nineteen eighties, prominent networked file systems were developed and reached widespread adoption among enterprise businesses and institutions. A few of these, notably Networked File System (NFS) and Server Message Block (SMB), survived the transition into the Internet era and the successors of these protocols remain th...

UNIX secure server : a free, secure, and functional server example

OpenAIRE

Sastre, Hugo

2016-01-01

The purpose of this thesis work was to introduce UNIX server as a personal server but also as a start point for investigation and developing at a professional level. The objective of this thesis was to build a secure server providing not only a FTP server but also an HTTP server and a cloud system for remote backups. OpenBSD was used as the operating system. OpenBSD is a UNIX-like operating system made by hackers for hackers. The difference with other systems that might partially provid...

MiSTIC, an integrated platform for the analysis of heterogeneity in large tumour transcriptome datasets.

Science.gov (United States)

Lemieux, Sebastien; Sargeant, Tobias; Laperrière, David; Ismail, Houssam; Boucher, Geneviève; Rozendaal, Marieke; Lavallée, Vincent-Philippe; Ashton-Beaucage, Dariel; Wilhelm, Brian; Hébert, Josée; Hilton, Douglas J; Mader, Sylvie; Sauvageau, Guy

2017-07-27

Genome-wide transcriptome profiling has enabled non-supervised classification of tumours, revealing different sub-groups characterized by specific gene expression features. However, the biological significance of these subtypes remains for the most part unclear. We describe herein an interactive platform, Minimum Spanning Trees Inferred Clustering (MiSTIC), that integrates the direct visualization and comparison of the gene correlation structure between datasets, the analysis of the molecular causes underlying co-variations in gene expression in cancer samples, and the clinical annotation of tumour sets defined by the combined expression of selected biomarkers. We have used MiSTIC to highlight the roles of specific transcription factors in breast cancer subtype specification, to compare the aspects of tumour heterogeneity targeted by different prognostic signatures, and to highlight biomarker interactions in AML. A version of MiSTIC preloaded with datasets described herein can be accessed through a public web server (http://mistic.iric.ca); in addition, the MiSTIC software package can be obtained (github.com/iric-soft/MiSTIC) for local use with personalized datasets. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

CTserver: A Computational Thermodynamics Server for the Geoscience Community

Science.gov (United States)

Kress, V. C.; Ghiorso, M. S.

2006-12-01

The CTserver platform is an Internet-based computational resource that provides on-demand services in Computational Thermodynamics (CT) to a diverse geoscience user base. This NSF-supported resource can be accessed at ctserver.ofm-research.org. The CTserver infrastructure leverages a high-quality and rigorously tested software library of routines for computing equilibrium phase assemblages and for evaluating internally consistent thermodynamic properties of materials, e.g. mineral solid solutions and a variety of geological fluids, including magmas. Thermodynamic models are currently available for 167 phases. Recent additions include Duan, Møller and Weare's model for supercritical C-O-H-S, extended to include SO2 and S2 species, and an entirely new associated solution model for O-S-Fe-Ni sulfide liquids. This software library is accessed via the CORBA Internet protocol for client-server communication. CORBA provides a standardized, object-oriented, language and platform independent, fast, low-bandwidth interface to phase property modules running on the server cluster. Network transport, language translation and resource allocation are handled by the CORBA interface. Users access server functionality in two principal ways. Clients written as browser- based Java applets may be downloaded which provide specific functionality such as retrieval of thermodynamic properties of phases, computation of phase equilibria for systems of specified composition, or modeling the evolution of these systems along some particular reaction path. This level of user interaction requires minimal programming effort and is ideal for classroom use. A more universal and flexible mode of CTserver access involves making remote procedure calls from user programs directly to the server public interface. The CTserver infrastructure relieves the user of the burden of implementing and testing the often complex thermodynamic models of real liquids and solids. A pilot application of this distributed

CalFitter: a web server for analysis of protein thermal denaturation data.

Science.gov (United States)

Mazurenko, Stanislav; Stourac, Jan; Kunka, Antonin; Nedeljkovic, Sava; Bednar, David; Prokop, Zbynek; Damborsky, Jiri

2018-05-14

Despite significant advances in the understanding of protein structure-function relationships, revealing protein folding pathways still poses a challenge due to a limited number of relevant experimental tools. Widely-used experimental techniques, such as calorimetry or spectroscopy, critically depend on a proper data analysis. Currently, there are only separate data analysis tools available for each type of experiment with a limited model selection. To address this problem, we have developed the CalFitter web server to be a unified platform for comprehensive data fitting and analysis of protein thermal denaturation data. The server allows simultaneous global data fitting using any combination of input data types and offers 12 protein unfolding pathway models for selection, including irreversible transitions often missing from other tools. The data fitting produces optimal parameter values, their confidence intervals, and statistical information to define unfolding pathways. The server provides an interactive and easy-to-use interface that allows users to directly analyse input datasets and simulate modelled output based on the model parameters. CalFitter web server is available free at https://loschmidt.chemi.muni.cz/calfitter/.

Mining the SDSS SkyServer SQL queries log

Science.gov (United States)

Hirota, Vitor M.; Santos, Rafael; Raddick, Jordan; Thakar, Ani

2016-05-01

SkyServer, the Internet portal for the Sloan Digital Sky Survey (SDSS) astronomic catalog, provides a set of tools that allows data access for astronomers and scientific education. One of SkyServer data access interfaces allows users to enter ad-hoc SQL statements to query the catalog. SkyServer also presents some template queries that can be used as basis for more complex queries. This interface has logged over 330 million queries submitted since 2001. It is expected that analysis of this data can be used to investigate usage patterns, identify potential new classes of queries, find similar queries, etc. and to shed some light on how users interact with the Sloan Digital Sky Survey data and how scientists have adopted the new paradigm of e-Science, which could in turn lead to enhancements on the user interfaces and experience in general. In this paper we review some approaches to SQL query mining, apply the traditional techniques used in the literature and present lessons learned, namely, that the general text mining approach for feature extraction and clustering does not seem to be adequate for this type of data, and, most importantly, we find that this type of analysis can result in very different queries being clustered together.

MCSA Windows Server 2012 R2 administration study guide exam 70-411

CERN Document Server

Panek, William

2015-01-01

Complete exam coverage, hands-on practice, and interactive studytools for the MCSA: Administering Windows Server 2012 R2 exam70-411 MCSA: Windows Server 2012 R2 Administration Study Guide: Exam70-411 provides comprehensive preparation for exam 70-411:Administering Windows Server 2012 R2. With full coverage of allexam domains, this guide contains everything you need to know to befully prepared on test day. Real-world scenarios illustrate thepractical applications of the lessons, and hands-on exercises allowyou to test yourself against everyday tasks. You get access to aninteractive practice te

Comprehensive Dataset and Reports of the Mamala Bay Study during 1993-1995 on Oahu, Hawaii (NODC Accession 0000030)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains comprehensive dataset and reports collected in support of the Mamala Bay Study during 1993-1995. Physical, chemical, biological, and...

Freiburg RNA Tools: a web server integrating INTARNA, EXPARNA and LOCARNA.

Science.gov (United States)

Smith, Cameron; Heyne, Steffen; Richter, Andreas S; Will, Sebastian; Backofen, Rolf

2010-07-01

The Freiburg RNA tools web server integrates three tools for the advanced analysis of RNA in a common web-based user interface. The tools IntaRNA, ExpaRNA and LocARNA support the prediction of RNA-RNA interaction, exact RNA matching and alignment of RNA, respectively. The Freiburg RNA tools web server and the software packages of the stand-alone tools are freely accessible at http://rna.informatik.uni-freiburg.de.

Online characterization of planetary surfaces: PlanetServer, an open-source analysis and visualization tool

Science.gov (United States)

Marco Figuera, R.; Pham Huu, B.; Rossi, A. P.; Minin, M.; Flahaut, J.; Halder, A.

2018-01-01

The lack of open-source tools for hyperspectral data visualization and analysis creates a demand for new tools. In this paper we present the new PlanetServer, a set of tools comprising a web Geographic Information System (GIS) and a recently developed Python Application Programming Interface (API) capable of visualizing and analyzing a wide variety of hyperspectral data from different planetary bodies. Current WebGIS open-source tools are evaluated in order to give an overview and contextualize how PlanetServer can help in this matters. The web client is thoroughly described as well as the datasets available in PlanetServer. Also, the Python API is described and exposed the reason of its development. Two different examples of mineral characterization of different hydrosilicates such as chlorites, prehnites and kaolinites in the Nili Fossae area on Mars are presented. As the obtained results show positive outcome in hyperspectral analysis and visualization compared to previous literature, we suggest using the PlanetServer approach for such investigations.

The Medicago truncatula gene expression atlas web server

Directory of Open Access Journals (Sweden)

Tang Yuhong

2009-12-01

Full Text Available Abstract Background Legumes (Leguminosae or Fabaceae play a major role in agriculture. Transcriptomics studies in the model legume species, Medicago truncatula, are instrumental in helping to formulate hypotheses about the role of legume genes. With the rapid growth of publically available Affymetrix GeneChip Medicago Genome Array GeneChip data from a great range of tissues, cell types, growth conditions, and stress treatments, the legume research community desires an effective bioinformatics system to aid efforts to interpret the Medicago genome through functional genomics. We developed the Medicago truncatula Gene Expression Atlas (MtGEA web server for this purpose. Description The Medicago truncatula Gene Expression Atlas (MtGEA web server is a centralized platform for analyzing the Medicago transcriptome. Currently, the web server hosts gene expression data from 156 Affymetrix GeneChip® Medicago genome arrays in 64 different experiments, covering a broad range of developmental and environmental conditions. The server enables flexible, multifaceted analyses of transcript data and provides a range of additional information about genes, including different types of annotation and links to the genome sequence, which help users formulate hypotheses about gene function. Transcript data can be accessed using Affymetrix probe identification number, DNA sequence, gene name, functional description in natural language, GO and KEGG annotation terms, and InterPro domain number. Transcripts can also be discovered through co-expression or differential expression analysis. Flexible tools to select a subset of experiments and to visualize and compare expression profiles of multiple genes have been implemented. Data can be downloaded, in part or full, in a tabular form compatible with common analytical and visualization software. The web server will be updated on a regular basis to incorporate new gene expression data and genome annotation, and is accessible

SQL Server 2012 data integration recipes solutions for integration services and other ETL tools

CERN Document Server

Aspin, Adam

2012-01-01

SQL Server 2012 Data Integration Recipes provides focused and practical solutions to real world problems of data integration. Need to import data into SQL Server from an outside source? Need to export data and send it to another system? SQL Server 2012 Data Integration Recipes has your back. You'll find solutions for importing from Microsoft Office data stores such as Excel and Access, from text files such as CSV files, from XML, from other database brands such as Oracle and MySQL, and even from other SQL Server databases. You'll learn techniques for managing metadata, transforming data to mee

Pengaruh Perangkat Server Terhadap Kualitas Pengontrolan Jarak Jauh Melalui Internet

OpenAIRE

Gunawan; R, Imam Muslim

2017-01-01

Internet greatly assist people in improving their quality of life. Almost all areas of human life can be accessed using the internet. Human aided by the internet that provides all sorts of information that they need. Along with the development of the Internet network infrastructure remotely control began to change using the internet. In this study using notebooks and servers Raspberry Pi to find out the quality control of each device server used. In this study we investigate the possibility o...

The PETfold and PETcofold web servers for intra- and intermolecular structures of multiple RNA sequences

DEFF Research Database (Denmark)

Seemann, Ernst Stefan; Menzel, Karl Peter; Backofen, Rolf

2011-01-01

gene. We present web servers to analyze multiple RNA sequences for common RNA structure and for RNA interaction sites. The web servers are based on the recent PET (Probabilistic Evolutionary and Thermodynamic) models PETfold and PETcofold, but add user friendly features ranging from a graphical layer...... to interactive usage of the predictors. Additionally, the web servers provide direct access to annotated RNA alignments, such as the Rfam 10.0 database and multiple alignments of 16 vertebrate genomes with human. The web servers are freely available at: http://rth.dk/resources/petfold/...

The ASDEX Upgrade Parameter Server

Energy Technology Data Exchange (ETDEWEB)

Neu, Gregor, E-mail: gregor.neu@ipp.mpg.de [Max-Planck-Institut für Plasmaphysik, Boltzmannstr. 2, 85748 Garching (Germany); Cole, Richard [Unlimited Computer Systems, Seeshaupter Str. 15, 82393 Iffeldorf (Germany); Gräter, Alex [Max-Planck-Institut für Plasmaphysik, Boltzmannstr. 2, 85748 Garching (Germany); Lüddecke, Klaus [Unlimited Computer Systems, Seeshaupter Str. 15, 82393 Iffeldorf (Germany); Rapson, Christopher J.; Raupp, Gerhard; Treutterer, Wolfgang; Zasche, Dietrich; Zehetbauer, Thomas [Max-Planck-Institut für Plasmaphysik, Boltzmannstr. 2, 85748 Garching (Germany)

2015-10-15

Highlights: • We describe our main tool in the plasma control configuration process. • Parameter access and computation are configurable with XML files. • Simple implementation of in situ tests by rerouting requests to test data. • Pulse specific overriding of parameters. - Abstract: Concepts for the configuration of plant systems and plasma control of modern devices such as ITER and W7-X are based on global data structures, or “pulse schedules” or “experiment programs”, which specify all physics characteristics (waveforms for controlled actuators and plasma quantities) and all technical characteristics of the plant systems (diagnostics and actuators operation settings) for a planned pulse. At ASDEX Upgrade we use different approach. We observed that the physics characteristics driving the discharge control system (DCS) are frequently modified on a pulse-to-pulse basis. Plant system operation, however, relies on technical standard settings, or “basic configurations” to provide guaranteed resources or services, which evolve according to longer term session or campaign operation schedules. This is why AUG manages technical configuration items separately from physics items. Consistent computation of the DCS configuration requires access to all this physics and technical data, which include the discharge programme (DP), settings of actuator systems and real-time diagnostics, the current system state and a database of static parameters. A Parameter Server provides a unified view on all these parameter sets and acts as the central point of access. We describe the functionality and architecture of the Parameter Server and its embedding into the control environment.

Effect Through Broadcasting System Access Point For Video Transmission

Directory of Open Access Journals (Sweden)

Leni Marlina

2015-08-01

Full Text Available Most universities are already implementing wired and wireless network that is used to access integrated information systems and the Internet. At present it is important to do research on the influence of the broadcasting system through the access point for video transmitter learning in the university area. At every university computer network through the access point must also use the cable in its implementation. These networks require cables that will connect and transmit data from one computer to another computer. While wireless networks of computers connected through radio waves. This research will be a test or assessment of how the influence of the network using the WLAN access point for video broadcasting means learning from the server to the client. Instructional video broadcasting from the server to the client via the access point will be used for video broadcasting means of learning. This study aims to understand how to build a wireless network by using an access point. It also builds a computer server as instructional videos supporting software that can be used for video server that will be emitted by broadcasting via the access point and establish a system of transmitting video from the server to the client via the access point.

CCTOP: a Consensus Constrained TOPology prediction web server.

Science.gov (United States)

Dobson, László; Reményi, István; Tusnády, Gábor E

2015-07-01

The Consensus Constrained TOPology prediction (CCTOP; http://cctop.enzim.ttk.mta.hu) server is a web-based application providing transmembrane topology prediction. In addition to utilizing 10 different state-of-the-art topology prediction methods, the CCTOP server incorporates topology information from existing experimental and computational sources available in the PDBTM, TOPDB and TOPDOM databases using the probabilistic framework of hidden Markov model. The server provides the option to precede the topology prediction with signal peptide prediction and transmembrane-globular protein discrimination. The initial result can be recalculated by (de)selecting any of the prediction methods or mapped experiments or by adding user specified constraints. CCTOP showed superior performance to existing approaches. The reliability of each prediction is also calculated, which correlates with the accuracy of the per protein topology prediction. The prediction results and the collected experimental information are visualized on the CCTOP home page and can be downloaded in XML format. Programmable access of the CCTOP server is also available, and an example of client-side script is provided. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

Designing a scalable video-on-demand server with data sharing

Science.gov (United States)

Lim, Hyeran; Du, David H. C.

2001-01-01

As current disk space and transfer speed increase, the bandwidth between a server and its disks has become critical for video-on-demand (VOD) services. Our VOD server consists of several hosts sharing data on disks through a ring-based network. Data sharing provided by the spatial-reuse ring network between servers and disks not only increases the utilization towards full bandwidth but also improves the availability of videos. Striping and replication methods are introduced in order to improve the efficiency of our VOD server system as well as the availability of videos. We consider tow kinds of resources of a VOD server system. Given a representative access profile, our intention is to propose an algorithm to find an initial condition, place videos on disks in the system successfully. If any copy of a video cannot be placed due to lack of resources, more servers/disks are added. When all videos are place on the disks by our algorithm, the final configuration is determined with indicator of how tolerable it is against the fluctuation in demand of videos. Considering it is a NP-hard problem, our algorithm generates the final configuration with O(M log M) at best, where M is the number of movies.

Cross-Dataset Analysis and Visualization Driven by Expressive Web Services

Science.gov (United States)

Alexandru Dumitru, Mircea; Catalin Merticariu, Vlad

2015-04-01

The deluge of data that is hitting us every day from satellite and airborne sensors is changing the workflow of environmental data analysts and modelers. Web geo-services play now a fundamental role, and are no longer needed to preliminary download and store the data, but rather they interact in real-time with GIS applications. Due to the very large amount of data that is curated and made available by web services, it is crucial to deploy smart solutions for optimizing network bandwidth, reducing duplication of data and moving the processing closer to the data. In this context we have created a visualization application for analysis and cross-comparison of aerosol optical thickness datasets. The application aims to help researchers identify and visualize discrepancies between datasets coming from various sources, having different spatial and time resolutions. It also acts as a proof of concept for integration of OGC Web Services under a user-friendly interface that provides beautiful visualizations of the explored data. The tool was built on top of the World Wind engine, a Java based virtual globe built by NASA and the open source community. For data retrieval and processing we exploited the OGC Web Coverage Service potential: the most exciting aspect being its processing extension, a.k.a. the OGC Web Coverage Processing Service (WCPS) standard. A WCPS-compliant service allows a client to execute a processing query on any coverage offered by the server. By exploiting a full grammar, several different kinds of information can be retrieved from one or more datasets together: scalar condensers, cross-sectional profiles, comparison maps and plots, etc. This combination of technology made the application versatile and portable. As the processing is done on the server-side, we ensured that the minimal amount of data is transferred and that the processing is done on a fully-capable server, leaving the client hardware resources to be used for rendering the visualization

Deep Recurrent Model for Server Load and Performance Prediction in Data Center

Directory of Open Access Journals (Sweden)

Zheng Huang

2017-01-01

Full Text Available Recurrent neural network (RNN has been widely applied to many sequential tagging tasks such as natural language process (NLP and time series analysis, and it has been proved that RNN works well in those areas. In this paper, we propose using RNN with long short-term memory (LSTM units for server load and performance prediction. Classical methods for performance prediction focus on building relation between performance and time domain, which makes a lot of unrealistic hypotheses. Our model is built based on events (user requests, which is the root cause of server performance. We predict the performance of the servers using RNN-LSTM by analyzing the log of servers in data center which contains user’s access sequence. Previous work for workload prediction could not generate detailed simulated workload, which is useful in testing the working condition of servers. Our method provides a new way to reproduce user request sequence to solve this problem by using RNN-LSTM. Experiment result shows that our models get a good performance in generating load and predicting performance on the data set which has been logged in online service. We did experiments with nginx web server and mysql database server, and our methods can been easily applied to other servers in data center.

PANNZER2: a rapid functional annotation web server.

Science.gov (United States)

Törönen, Petri; Medlar, Alan; Holm, Liisa

2018-05-08

The unprecedented growth of high-throughput sequencing has led to an ever-widening annotation gap in protein databases. While computational prediction methods are available to make up the shortfall, a majority of public web servers are hindered by practical limitations and poor performance. Here, we introduce PANNZER2 (Protein ANNotation with Z-scoRE), a fast functional annotation web server that provides both Gene Ontology (GO) annotations and free text description predictions. PANNZER2 uses SANSparallel to perform high-performance homology searches, making bulk annotation based on sequence similarity practical. PANNZER2 can output GO annotations from multiple scoring functions, enabling users to see which predictions are robust across predictors. Finally, PANNZER2 predictions scored within the top 10 methods for molecular function and biological process in the CAFA2 NK-full benchmark. The PANNZER2 web server is updated on a monthly schedule and is accessible at http://ekhidna2.biocenter.helsinki.fi/sanspanz/. The source code is available under the GNU Public Licence v3.

Windows 2012 Server network security securing your Windows network systems and infrastructure

CERN Document Server

Rountree, Derrick

2013-01-01

Windows 2012 Server Network Security provides the most in-depth guide to deploying and maintaining a secure Windows network. The book drills down into all the new features of Windows 2012 and provides practical, hands-on methods for securing your Windows systems networks, including: Secure remote access Network vulnerabilities and mitigations DHCP installations configuration MAC filtering DNS server security WINS installation configuration Securing wired and wireless connections Windows personal firewall

GeoServer cookbook

CERN Document Server

Iacovella, Stefano

2014-01-01

This book is ideal for GIS experts, developers, and system administrators who have had a first glance at GeoServer and who are eager to explore all its features in order to configure professional map servers. Basic knowledge of GIS and GeoServer is required.

Enhancing Access to Drought Information Using the CUAHSI Hydrologic Information System

Science.gov (United States)

Schreuders, K. A.; Tarboton, D. G.; Horsburgh, J. S.; Sen Gupta, A.; Reeder, S.

2011-12-01

The National Drought Information System (NIDIS) Upper Colorado River Basin pilot study is investigating and establishing capabilities for better dissemination of drought information for early warning and management. As part of this study we are using and extending functionality from the Consortium of Universities for the Advancement of Hydrologic Science, Inc. (CUAHSI) Hydrologic Information System (HIS) to provide better access to drought-related data in the Upper Colorado River Basin. The CUAHSI HIS is a federated system for sharing hydrologic data. It is comprised of multiple data servers, referred to as HydroServers, that publish data in a standard XML format called Water Markup Language (WaterML), using web services referred to as WaterOneFlow web services. HydroServers can also publish geospatial data using Open Geospatial Consortium (OGC) web map, feature and coverage services and are capable of hosting web and map applications that combine geospatial datasets with observational data served via web services. HIS also includes a centralized metadata catalog that indexes data from registered HydroServers and a data access client referred to as HydroDesktop. For NIDIS, we have established a HydroServer to publish drought index values as well as the input data used in drought index calculations. Primary input data required for drought index calculation include streamflow, precipitation, reservoir storages, snow water equivalent, and soil moisture. We have developed procedures to redistribute the input data to the time and space scales chosen for drought index calculation, namely half monthly time intervals for HUC 10 subwatersheds. The spatial redistribution approaches used for each input parameter are dependent on the spatial linkages for that parameter, i.e., the redistribution procedure for streamflow is dependent on the upstream/downstream connectivity of the stream network, and the precipitation redistribution procedure is dependent on elevation to account

EarthServer: Cross-Disciplinary Earth Science Through Data Cube Analytics

Science.gov (United States)

Baumann, P.; Rossi, A. P.

2016-12-01

The unprecedented increase of imagery, in-situ measurements, and simulation data produced by Earth (and Planetary) Science observations missions bears a rich, yet not leveraged potential for getting insights from integrating such diverse datasets and transform scientific questions into actual queries to data, formulated in a standardized way.The intercontinental EarthServer [1] initiative is demonstrating new directions for flexible, scalable Earth Science services based on innovative NoSQL technology. Researchers from Europe, the US and Australia have teamed up to rigorously implement the concept of the datacube. Such a datacube may have spatial and temporal dimensions (such as a satellite image time series) and may unite an unlimited number of scenes. Independently from whatever efficient data structuring a server network may perform internally, users (scientist, planners, decision makers) will always see just a few datacubes they can slice and dice.EarthServer has established client [2] and server technology for such spatio-temporal datacubes. The underlying scalable array engine, rasdaman [3,4], enables direct interaction, including 3-D visualization, common EO data processing, and general analytics. Services exclusively rely on the open OGC "Big Geo Data" standards suite, the Web Coverage Service (WCS). Conversely, EarthServer has shaped and advanced WCS based on the experience gained. The first phase of EarthServer has advanced scalable array database technology into 150+ TB services. Currently, Petabyte datacubes are being built for ad-hoc and cross-disciplinary querying, e.g. using climate, Earth observation and ocean data.We will present the EarthServer approach, its impact on OGC / ISO / INSPIRE standardization, and its platform technology, rasdaman.References: [1] Baumann, et al. (2015) DOI: 10.1080/17538947.2014.1003106 [2] Hogan, P., (2011) NASA World Wind, Proceedings of the 2nd International Conference on Computing for Geospatial Research

Accessing the SEED genome databases via Web services API: tools for programmers.

Science.gov (United States)

Disz, Terry; Akhter, Sajia; Cuevas, Daniel; Olson, Robert; Overbeek, Ross; Vonstein, Veronika; Stevens, Rick; Edwards, Robert A

2010-06-14

The SEED integrates many publicly available genome sequences into a single resource. The database contains accurate and up-to-date annotations based on the subsystems concept that leverages clustering between genomes and other clues to accurately and efficiently annotate microbial genomes. The backend is used as the foundation for many genome annotation tools, such as the Rapid Annotation using Subsystems Technology (RAST) server for whole genome annotation, the metagenomics RAST server for random community genome annotations, and the annotation clearinghouse for exchanging annotations from different resources. In addition to a web user interface, the SEED also provides Web services based API for programmatic access to the data in the SEED, allowing the development of third-party tools and mash-ups. The currently exposed Web services encompass over forty different methods for accessing data related to microbial genome annotations. The Web services provide comprehensive access to the database back end, allowing any programmer access to the most consistent and accurate genome annotations available. The Web services are deployed using a platform independent service-oriented approach that allows the user to choose the most suitable programming platform for their application. Example code demonstrate that Web services can be used to access the SEED using common bioinformatics programming languages such as Perl, Python, and Java. We present a novel approach to access the SEED database. Using Web services, a robust API for access to genomics data is provided, without requiring large volume downloads all at once. The API ensures timely access to the most current datasets available, including the new genomes as soon as they come online.

ARCAS (ACACIA Regional Climate-data Access System) -- a Web Access System for Climate Model Data Access, Visualization and Comparison

Science.gov (United States)

Hakkarinen, C.; Brown, D.; Callahan, J.; hankin, S.; de Koningh, M.; Middleton-Link, D.; Wigley, T.

2001-05-01

A Web-based access system to climate model output data sets for intercomparison and analysis has been produced, using the NOAA-PMEL developed Live Access Server software as host server and Ferret as the data serving and visualization engine. Called ARCAS ("ACACIA Regional Climate-data Access System"), and publicly accessible at http://dataserver.ucar.edu/arcas, the site currently serves climate model outputs from runs of the NCAR Climate System Model for the 21st century, for Business as Usual and Stabilization of Greenhouse Gas Emission scenarios. Users can select, download, and graphically display single variables or comparisons of two variables from either or both of the CSM model runs, averaged for monthly, seasonal, or annual time resolutions. The time length of the averaging period, and the geographical domain for download and display, are fully selectable by the user. A variety of arithmetic operations on the data variables can be computed "on-the-fly", as defined by the user. Expansions of the user-selectable options for defining analysis options, and for accessing other DOD-compatible ("Distributed Ocean Data System-compatible") data sets, residing at locations other than the NCAR hardware server on which ARCAS operates, are planned for this year. These expansions are designed to allow users quick and easy-to-operate web-based access to the largest possible selection of climate model output data sets available throughout the world.

The web server of IBM's Bioinformatics and Pattern Discovery group.

Science.gov (United States)

Huynh, Tien; Rigoutsos, Isidore; Parida, Laxmi; Platt, Daniel; Shibuya, Tetsuo

2003-07-01

We herein present and discuss the services and content which are available on the web server of IBM's Bioinformatics and Pattern Discovery group. The server is operational around the clock and provides access to a variety of methods that have been published by the group's members and collaborators. The available tools correspond to applications ranging from the discovery of patterns in streams of events and the computation of multiple sequence alignments, to the discovery of genes in nucleic acid sequences and the interactive annotation of amino acid sequences. Additionally, annotations for more than 70 archaeal, bacterial, eukaryotic and viral genomes are available on-line and can be searched interactively. The tools and code bundles can be accessed beginning at http://cbcsrv.watson.ibm.com/Tspd.html whereas the genomics annotations are available at http://cbcsrv.watson.ibm.com/Annotations/.

QuIN: A Web Server for Querying and Visualizing Chromatin Interaction Networks.

Directory of Open Access Journals (Sweden)

Asa Thibodeau

2016-06-01

Full Text Available Recent studies of the human genome have indicated that regulatory elements (e.g. promoters and enhancers at distal genomic locations can interact with each other via chromatin folding and affect gene expression levels. Genomic technologies for mapping interactions between DNA regions, e.g., ChIA-PET and HiC, can generate genome-wide maps of interactions between regulatory elements. These interaction datasets are important resources to infer distal gene targets of non-coding regulatory elements and to facilitate prioritization of critical loci for important cellular functions. With the increasing diversity and complexity of genomic information and public ontologies, making sense of these datasets demands integrative and easy-to-use software tools. Moreover, network representation of chromatin interaction maps enables effective data visualization, integration, and mining. Currently, there is no software that can take full advantage of network theory approaches for the analysis of chromatin interaction datasets. To fill this gap, we developed a web-based application, QuIN, which enables: 1 building and visualizing chromatin interaction networks, 2 annotating networks with user-provided private and publicly available functional genomics and interaction datasets, 3 querying network components based on gene name or chromosome location, and 4 utilizing network based measures to identify and prioritize critical regulatory targets and their direct and indirect interactions.QuIN's web server is available at http://quin.jax.org QuIN is developed in Java and JavaScript, utilizing an Apache Tomcat web server and MySQL database and the source code is available under the GPLV3 license available on GitHub: https://github.com/UcarLab/QuIN/.

QuIN: A Web Server for Querying and Visualizing Chromatin Interaction Networks.

Science.gov (United States)

Thibodeau, Asa; Márquez, Eladio J; Luo, Oscar; Ruan, Yijun; Menghi, Francesca; Shin, Dong-Guk; Stitzel, Michael L; Vera-Licona, Paola; Ucar, Duygu

2016-06-01

Recent studies of the human genome have indicated that regulatory elements (e.g. promoters and enhancers) at distal genomic locations can interact with each other via chromatin folding and affect gene expression levels. Genomic technologies for mapping interactions between DNA regions, e.g., ChIA-PET and HiC, can generate genome-wide maps of interactions between regulatory elements. These interaction datasets are important resources to infer distal gene targets of non-coding regulatory elements and to facilitate prioritization of critical loci for important cellular functions. With the increasing diversity and complexity of genomic information and public ontologies, making sense of these datasets demands integrative and easy-to-use software tools. Moreover, network representation of chromatin interaction maps enables effective data visualization, integration, and mining. Currently, there is no software that can take full advantage of network theory approaches for the analysis of chromatin interaction datasets. To fill this gap, we developed a web-based application, QuIN, which enables: 1) building and visualizing chromatin interaction networks, 2) annotating networks with user-provided private and publicly available functional genomics and interaction datasets, 3) querying network components based on gene name or chromosome location, and 4) utilizing network based measures to identify and prioritize critical regulatory targets and their direct and indirect interactions. QuIN's web server is available at http://quin.jax.org QuIN is developed in Java and JavaScript, utilizing an Apache Tomcat web server and MySQL database and the source code is available under the GPLV3 license available on GitHub: https://github.com/UcarLab/QuIN/.

Beginning SQL Server Modeling Model-driven Application Development in SQL Server

CERN Document Server

Weller, Bart

2010-01-01

Get ready for model-driven application development with SQL Server Modeling! This book covers Microsoft's SQL Server Modeling (formerly known under the code name "Oslo") in detail and contains the information you need to be successful with designing and implementing workflow modeling. Beginning SQL Server Modeling will help you gain a comprehensive understanding of how to apply DSLs and other modeling components in the development of SQL Server implementations. Most importantly, after reading the book and working through the examples, you will have considerable experience using SQL M

Advancing the Power and Utility of Server-Side Aggregation

Science.gov (United States)

Fulker, Dave; Gallagher, James

2016-01-01

During the upcoming Summer 2016 meeting of the ESIP Federation (July 19-22), OpenDAP will hold a Developers and Users Workshop. While a broad set of topics will be covered, a key focus is capitalizing on recent EOSDIS-sponsored advances in Hyrax, OPeNDAPs own software for server-side realization of the DAP2 and DAP4 protocols. These Hyrax advances are as important to data users as to data providers, and the workshop will include hands-on experiences of value to both. Specifically, a balanced set of presentations and hands-on tutorials will address advances in1.server installation,2.server configuration,3.Hyrax aggregation capabilities,4.support for data-access from clients that are HTTP-based, JSON-based or OGC-compliant (especially WCS and WMS),5.support for DAP4,6.use and extension of server-side computational capabilities, and7.several performance-affecting matters.Topics 2 through 7 will be relevant to data consumers, data providers andnotably, due to the open-source nature of all OPeNDAP softwareto developers wishing to extend Hyrax, to build compatible clients and servers, andor to employ Hyrax as middleware that enables interoperability across a variety of end-user and source-data contexts. A session for contributed talks will elaborate the topics listed above and embrace additional ones.

Design of SIP transformation server for efficient media negotiation

Science.gov (United States)

Pack, Sangheon; Paik, Eun Kyoung; Choi, Yanghee

2001-07-01

Voice over IP (VoIP) is one of the advanced services supported by the next generation mobile communication. VoIP should support various media formats and terminals existing together. This heterogeneous environment may prevent diverse users from establishing VoIP sessions among them. To solve the problem an efficient media negotiation mechanism is required. In this paper, we propose the efficient media negotiation architecture using the transformation server and the Intelligent Location Server (ILS). The transformation server is an extended Session Initiation Protocol (SIP) proxy server. It can modify an unacceptable session INVITE message into an acceptable one using the ILS. The ILS is a directory server based on the Lightweight Directory Access Protocol (LDAP) that keeps userí*s location information and available media information. The proposed architecture can eliminate an unnecessary response and re-INVITE messages of the standard SIP architecture. It takes only 1.5 round trip times to negotiate two different media types while the standard media negotiation mechanism takes 2.5 round trip times. The extra processing time in message handling is negligible in comparison to the reduced round trip time. The experimental results show that the session setup time in the proposed architecture is less than the setup time in the standard SIP. These results verify that the proposed media negotiation mechanism is more efficient in solving diversity problems.

Web-based access to near real-time and archived high-density time-series data: cyber infrastructure challenges & developments in the open-source Waveform Server

Science.gov (United States)

Reyes, J. C.; Vernon, F. L.; Newman, R. L.; Steidl, J. H.

2010-12-01

The Waveform Server is an interactive web-based interface to multi-station, multi-sensor and multi-channel high-density time-series data stored in Center for Seismic Studies (CSS) 3.0 schema relational databases (Newman et al., 2009). In the last twelve months, based on expanded specifications and current user feedback, both the server-side infrastructure and client-side interface have been extensively rewritten. The Python Twisted server-side code-base has been fundamentally modified to now present waveform data stored in cluster-based databases using a multi-threaded architecture, in addition to supporting the pre-existing single database model. This allows interactive web-based access to high-density (broadband @ 40Hz to strong motion @ 200Hz) waveform data that can span multiple years; the common lifetime of broadband seismic networks. The client-side interface expands on it's use of simple JSON-based AJAX queries to now incorporate a variety of User Interface (UI) improvements including standardized calendars for defining time ranges, applying on-the-fly data calibration to display SI-unit data, and increased rendering speed. This presentation will outline the various cyber infrastructure challenges we have faced while developing this application, the use-cases currently in existence, and the limitations of web-based application development.

Mastering Lync Server 2010

CERN Document Server

Winters, Nathan

2012-01-01

An in-depth guide on the leading Unified Communications platform Microsoft Lync Server 2010 maximizes communication capabilities in the workplace like no other Unified Communications (UC) solution. Written by experts who know Lync Server inside and out, this comprehensive guide shows you step by step how to administer the newest and most robust version of Lync Server. Along with clear and detailed instructions, learning is aided by exercise problems and real-world examples of established Lync Server environments. You'll gain the skills you need to effectively deploy Lync Server 2010 and be on

AlignMe—a membrane protein sequence alignment web server

Science.gov (United States)

Stamm, Marcus; Staritzbichler, René; Khafizov, Kamil; Forrest, Lucy R.

2014-01-01

We present a web server for pair-wise alignment of membrane protein sequences, using the program AlignMe. The server makes available two operational modes of AlignMe: (i) sequence to sequence alignment, taking two sequences in fasta format as input, combining information about each sequence from multiple sources and producing a pair-wise alignment (PW mode); and (ii) alignment of two multiple sequence alignments to create family-averaged hydropathy profile alignments (HP mode). For the PW sequence alignment mode, four different optimized parameter sets are provided, each suited to pairs of sequences with a specific similarity level. These settings utilize different types of inputs: (position-specific) substitution matrices, secondary structure predictions and transmembrane propensities from transmembrane predictions or hydrophobicity scales. In the second (HP) mode, each input multiple sequence alignment is converted into a hydrophobicity profile averaged over the provided set of sequence homologs; the two profiles are then aligned. The HP mode enables qualitative comparison of transmembrane topologies (and therefore potentially of 3D folds) of two membrane proteins, which can be useful if the proteins have low sequence similarity. In summary, the AlignMe web server provides user-friendly access to a set of tools for analysis and comparison of membrane protein sequences. Access is available at http://www.bioinfo.mpg.de/AlignMe PMID:24753425

Development of an online radiology case review system featuring interactive navigation of volumetric image datasets using advanced visualization techniques

International Nuclear Information System (INIS)

Yang, Hyun Kyung; Kim, Boh Kyoung; Jung, Ju Hyun; Kang, Heung Sik; Lee, Kyoung Ho; Woo, Hyun Soo; Jo, Jae Min; Lee, Min Hee

2015-01-01

To develop an online radiology case review system that allows interactive navigation of volumetric image datasets using advanced visualization techniques. Our Institutional Review Board approved the use of the patient data and waived the need for informed consent. We determined the following system requirements: volumetric navigation, accessibility, scalability, undemanding case management, trainee encouragement, and simulation of a busy practice. The system comprised a case registry server, client case review program, and commercially available cloud-based image viewing system. In the pilot test, we used 30 cases of low-dose abdomen computed tomography for the diagnosis of acute appendicitis. In each case, a trainee was required to navigate through the images and submit answers to the case questions. The trainee was then given the correct answers and key images, as well as the image dataset with annotations on the appendix. After evaluation of all cases, the system displayed the diagnostic accuracy and average review time, and the trainee was asked to reassess the failed cases. The pilot system was deployed successfully in a hands-on workshop course. We developed an online radiology case review system that allows interactive navigation of volumetric image datasets using advanced visualization techniques

Development of an online radiology case review system featuring interactive navigation of volumetric image datasets using advanced visualization techniques

Energy Technology Data Exchange (ETDEWEB)

Yang, Hyun Kyung; Kim, Boh Kyoung; Jung, Ju Hyun; Kang, Heung Sik; Lee, Kyoung Ho [Dept. of Radiology, Seoul National University Bundang Hospital, Seongnam (Korea, Republic of); Woo, Hyun Soo [Dept. of Radiology, SMG-SNU Boramae Medical Center, Seoul (Korea, Republic of); Jo, Jae Min [Dept. of Computer Science and Engineering, Seoul National University, Seoul (Korea, Republic of); Lee, Min Hee [Dept. of Radiology, Soonchunhyang University Bucheon Hospital, Bucheon (Korea, Republic of)

2015-11-15

To develop an online radiology case review system that allows interactive navigation of volumetric image datasets using advanced visualization techniques. Our Institutional Review Board approved the use of the patient data and waived the need for informed consent. We determined the following system requirements: volumetric navigation, accessibility, scalability, undemanding case management, trainee encouragement, and simulation of a busy practice. The system comprised a case registry server, client case review program, and commercially available cloud-based image viewing system. In the pilot test, we used 30 cases of low-dose abdomen computed tomography for the diagnosis of acute appendicitis. In each case, a trainee was required to navigate through the images and submit answers to the case questions. The trainee was then given the correct answers and key images, as well as the image dataset with annotations on the appendix. After evaluation of all cases, the system displayed the diagnostic accuracy and average review time, and the trainee was asked to reassess the failed cases. The pilot system was deployed successfully in a hands-on workshop course. We developed an online radiology case review system that allows interactive navigation of volumetric image datasets using advanced visualization techniques.

A Web Server for MACCS Magnetometer Data

Science.gov (United States)

Engebretson, Mark J.

1998-01-01

NASA Grant NAG5-3719 was provided to Augsburg College to support the development of a web server for the Magnetometer Array for Cusp and Cleft Studies (MACCS), a two-dimensional array of fluxgate magnetometers located at cusp latitudes in Arctic Canada. MACCS was developed as part of the National Science Foundation's GEM (Geospace Environment Modeling) Program, which was designed in part to complement NASA's Global Geospace Science programs during the decade of the 1990s. This report describes the successful use of these grant funds to support a working web page that provides both daily plots and file access to any user accessing the worldwide web. The MACCS home page can be accessed at http://space.augsburg.edu/space/MaccsHome.html.

Distributed data access in the sequential access model at the D0 experiment at Fermilab

International Nuclear Information System (INIS)

Terekhov, Igor; White, Victoria

2000-01-01

The authors present the Sequential Access Model (SAM), which is the data handling system for D0, one of two primary High Energy Experiments at Fermilab. During the next several years, the D0 experiment will store a total of about 1 PByte of data, including raw detector data and data processed at various levels. The design of SAM is not specific to the D0 experiment and carries few assumptions about the underlying mass storage level; its ideas are applicable to any sequential data access. By definition, in the sequential access mode a user application needs to process a stream of data, by accessing each data unit exactly once, the order of data units in the stream being irrelevant. The units of data are laid out sequentially in files. The adopted model allows for significant optimizations of system performance, decrease of user file latency and increase of overall throughput. In particular, caching is done with the knowledge of all the files needed in the near future, defined as all the files of the already running or submitted jobs. The bulk of the data is stored in files on tape in the mass storage system (MSS) called Enstore[2] and also developed at Fermilab. (The tape drives are served by an ADIC AML/2 Automated Tape Library). At any given time, SAM has a small fraction of the data cached on disk for processing. In the present paper, the authors discuss how data is delivered onto disk and how it is accessed by user applications. They will concentrate on data retrieval (consumption) from the MSS; when SAM is used for storing of data, the mechanisms are rather symmetrical. All of the data managed by SAM is cataloged in great detail in a relational database (ORACLE). The database also serves as the persistency mechanism for the SAM servers described in this paper. Any client or server in the SAM system which needs to store or retrieve information from the database does so through the interfaces of a CORBA-based database server. The users (physicists) use the

Disk Storage Server

CERN Multimedia

This model was a disk storage server used in the Data Centre up until 2012. Each tray contains a hard disk drive (see the 5TB hard disk drive on the main disk display section - this actually fits into one of the trays). There are 16 trays in all per server. There are hundreds of these servers mounted on racks in the Data Centre, as can be seen.

Group-Server Queues

OpenAIRE

Li, Quan-Lin; Ma, Jing-Yu; Xie, Mingzhou; Xia, Li

2017-01-01

By analyzing energy-efficient management of data centers, this paper proposes and develops a class of interesting {\\it Group-Server Queues}, and establishes two representative group-server queues through loss networks and impatient customers, respectively. Furthermore, such two group-server queues are given model descriptions and necessary interpretation. Also, simple mathematical discussion is provided, and simulations are made to study the expected queue lengths, the expected sojourn times ...

Protein Solvent-Accessibility Prediction by a Stacked Deep Bidirectional Recurrent Neural Network

Directory of Open Access Journals (Sweden)

Buzhong Zhang

2018-05-01

Full Text Available Residue solvent accessibility is closely related to the spatial arrangement and packing of residues. Predicting the solvent accessibility of a protein is an important step to understand its structure and function. In this work, we present a deep learning method to predict residue solvent accessibility, which is based on a stacked deep bidirectional recurrent neural network applied to sequence profiles. To capture more long-range sequence information, a merging operator was proposed when bidirectional information from hidden nodes was merged for outputs. Three types of merging operators were used in our improved model, with a long short-term memory network performing as a hidden computing node. The trained database was constructed from 7361 proteins extracted from the PISCES server using a cut-off of 25% sequence identity. Sequence-derived features including position-specific scoring matrix, physical properties, physicochemical characteristics, conservation score and protein coding were used to represent a residue. Using this method, predictive values of continuous relative solvent-accessible area were obtained, and then, these values were transformed into binary states with predefined thresholds. Our experimental results showed that our deep learning method improved prediction quality relative to current methods, with mean absolute error and Pearson’s correlation coefficient values of 8.8% and 74.8%, respectively, on the CB502 dataset and 8.2% and 78%, respectively, on the Manesh215 dataset.

Protein Solvent-Accessibility Prediction by a Stacked Deep Bidirectional Recurrent Neural Network.

Science.gov (United States)

Zhang, Buzhong; Li, Linqing; Lü, Qiang

2018-05-25

Residue solvent accessibility is closely related to the spatial arrangement and packing of residues. Predicting the solvent accessibility of a protein is an important step to understand its structure and function. In this work, we present a deep learning method to predict residue solvent accessibility, which is based on a stacked deep bidirectional recurrent neural network applied to sequence profiles. To capture more long-range sequence information, a merging operator was proposed when bidirectional information from hidden nodes was merged for outputs. Three types of merging operators were used in our improved model, with a long short-term memory network performing as a hidden computing node. The trained database was constructed from 7361 proteins extracted from the PISCES server using a cut-off of 25% sequence identity. Sequence-derived features including position-specific scoring matrix, physical properties, physicochemical characteristics, conservation score and protein coding were used to represent a residue. Using this method, predictive values of continuous relative solvent-accessible area were obtained, and then, these values were transformed into binary states with predefined thresholds. Our experimental results showed that our deep learning method improved prediction quality relative to current methods, with mean absolute error and Pearson's correlation coefficient values of 8.8% and 74.8%, respectively, on the CB502 dataset and 8.2% and 78%, respectively, on the Manesh215 dataset.

Web server attack analyzer

OpenAIRE

Mižišin, Michal

2013-01-01

Web server attack analyzer - Abstract The goal of this work was to create prototype of analyzer of injection flaws attacks on web server. Proposed solution combines capabilities of web application firewall and web server log analyzer. Analysis is based on configurable signatures defined by regular expressions. This paper begins with summary of web attacks, followed by detection techniques analysis on web servers, description and justification of selected implementation. In the end are charact...

Harvard Aging Brain Study : Dataset and accessibility

NARCIS (Netherlands)

Dagley, Alexander; LaPoint, Molly; Huijbers, Willem; Hedden, Trey; McLaren, Donald G.; Chatwal, Jasmeer P.; Papp, Kathryn V.; Amariglio, Rebecca E.; Blacker, Deborah; Rentz, Dorene M.; Johnson, Keith A.; Sperling, Reisa A.; Schultz, Aaron P.

2017-01-01

The Harvard Aging Brain Study is sharing its data with the global research community. The longitudinal dataset consists of a 284-subject cohort with the following modalities acquired: demographics, clinical assessment, comprehensive neuropsychological testing, clinical biomarkers, and neuroimaging.

Implementing a Data Quality Strategy to Simplify Access to Data

Science.gov (United States)

Druken, K. A.; Trenham, C. E.; Evans, B. J. K.; Richards, C. J.; Wang, J.; Wyborn, L. A.

2016-12-01

To ensure seamless programmatic access for data analysis (including machine learning), standardization of both data and services is vital. At the Australian National Computational Infrastructure (NCI) we have developed a Data Quality Strategy (DQS) that currently provides processes for: (1) the consistency of data structures in the underlying High Performance Data (HPD) platform; (2) quality control through compliance with recognized community standards; and (3) data quality assurance through demonstrated functionality across common platforms, tools and services. NCI hosts one of Australia's largest repositories (10+ PBytes) of research data collections spanning datasets from climate, coasts, oceans and geophysics through to astronomy, bioinformatics and the social sciences. A key challenge is the application of community-agreed data standards to the broad set of Earth systems and environmental data that are being used. Within these disciplines, data span a wide range of gridded, ungridded (i.e., line surveys, point clouds), and raster image types, as well as diverse coordinate reference projections and resolutions. By implementing our DQS we have seen progressive improvement in the quality of the datasets across the different subject domains, and through this, the ease by which the users can programmatically access the data, either in situ or via web services. As part of its quality control procedures, NCI has developed a compliance checker based upon existing domain standards. The DQS also includes extensive Functionality Testing which include readability by commonly used libraries (e.g., netCDF, HDF, GDAL, etc.); accessibility by data servers (e.g., THREDDS, Hyrax, GeoServer), validation against scientific analysis and programming platforms (e.g., Python, Matlab, QGIS); and visualization tools (e.g., ParaView, NASA Web World Wind). These tests ensure smooth interoperability between products and services as well as exposing unforeseen requirements and

Distill: a suite of web servers for the prediction of one-, two- and three-dimensional structural features of proteins

Directory of Open Access Journals (Sweden)

Walsh Ian

2006-09-01

Full Text Available Abstract Background We describe Distill, a suite of servers for the prediction of protein structural features: secondary structure; relative solvent accessibility; contact density; backbone structural motifs; residue contact maps at 6, 8 and 12 Angstrom; coarse protein topology. The servers are based on large-scale ensembles of recursive neural networks and trained on large, up-to-date, non-redundant subsets of the Protein Data Bank. Together with structural feature predictions, Distill includes a server for prediction of Cα traces for short proteins (up to 200 amino acids. Results The servers are state-of-the-art, with secondary structure predicted correctly for nearly 80% of residues (currently the top performance on EVA, 2-class solvent accessibility nearly 80% correct, and contact maps exceeding 50% precision on the top non-diagonal contacts. A preliminary implementation of the predictor of protein Cα traces featured among the top 20 Novel Fold predictors at the last CASP6 experiment as group Distill (ID 0348. The majority of the servers, including the Cα trace predictor, now take into account homology information from the PDB, when available, resulting in greatly improved reliability. Conclusion All predictions are freely available through a simple joint web interface and the results are returned by email. In a single submission the user can send protein sequences for a total of up to 32k residues to all or a selection of the servers. Distill is accessible at the address: http://distill.ucd.ie/distill/.

Implementing Citrix XenServer Quickstarter

CERN Document Server

Ahmed, Gohar

2013-01-01

Implementing Citrix XenServer Quick Starter is a practical, hands-on guide that will help you get started with the Citrix XenServer Virtualization technology with easy-to-follow instructions.Implementing Citrix XenServer Quick Starter is for system administrators who have little to no information on virtualization and specifically Citrix XenServer Virtualization. If you're managing a lot of physical servers and are tired of installing, deploying, updating, and managing physical machines on a daily basis over and over again, then you should probably explore your option of XenServer Virtualizati

Server virtualization solutions

OpenAIRE

Jonasts, Gusts

2012-01-01

Currently in the information technology sector that is responsible for a server infrastructure is a huge development in the field of server virtualization on x86 computer architecture. As a prerequisite for such a virtualization development is growth in server productivity and underutilization of available computing power. Several companies in the market are working on two virtualization architectures – hypervizor and hosting. In this paper several of virtualization products that use host...

Web Server Embedded System

Directory of Open Access Journals (Sweden)

Adharul Muttaqin

2014-07-01

Full Text Available Abstrak Embedded sistem saat ini menjadi perhatian khusus pada teknologi komputer, beberapa sistem operasi linux dan web server yang beraneka ragam juga sudah dipersiapkan untuk mendukung sistem embedded, salah satu aplikasi yang dapat digunakan dalam operasi pada sistem embedded adalah web server. Pemilihan web server pada lingkungan embedded saat ini masih jarang dilakukan, oleh karena itu penelitian ini dilakukan dengan menitik beratkan pada dua buah aplikasi web server yang tergolong memiliki fitur utama yang menawarkan “keringanan” pada konsumsi CPU maupun memori seperti Light HTTPD dan Tiny HTTPD. Dengan menggunakan parameter thread (users, ramp-up periods, dan loop count pada stress test embedded system, penelitian ini menawarkan solusi web server manakah diantara Light HTTPD dan Tiny HTTPD yang memiliki kecocokan fitur dalam penggunaan embedded sistem menggunakan beagleboard ditinjau dari konsumsi CPU dan memori. Hasil penelitian menunjukkan bahwa dalam hal konsumsi CPU pada beagleboard embedded system lebih disarankan penggunaan Light HTTPD dibandingkan dengan tiny HTTPD dikarenakan terdapat perbedaan CPU load yang sangat signifikan antar kedua layanan web tersebut Kata kunci: embedded system, web server Abstract Embedded systems are currently of particular concern in computer technology, some of the linux operating system and web server variegated also prepared to support the embedded system, one of the applications that can be used in embedded systems are operating on the web server. Selection of embedded web server on the environment is still rarely done, therefore this study was conducted with a focus on two web application servers belonging to the main features that offer a "lightness" to the CPU and memory consumption as Light HTTPD and Tiny HTTPD. By using the parameters of the thread (users, ramp-up periods, and loop count on a stress test embedded systems, this study offers a solution of web server which between the Light

Windows Server 2012 vulnerabilities and security

Directory of Open Access Journals (Sweden)

Gabriel R. López

2015-09-01

Full Text Available This investigation analyses the history of the vulnerabilities of the base system Windows Server 2012 highlighting the most critic vulnerabilities given every 4 months since its creation until the current date of the research. It was organized by the type of vulnerabilities based on the classification of the NIST. Next, given the official vulnerabilities of the system, the authors show how a critical vulnerability is treated by Microsoft in order to countermeasure the security flaw. Then, the authors present the recommended security approaches for Windows Server 2012, which focus on the baseline software given by Microsoft, update, patch and change management, hardening practices and the application of Active Directory Rights Management Services (AD RMS. AD RMS is considered as an important feature since it is able to protect the system even though it is compromised using access lists at a document level. Finally, the investigation of the state of the art related to the security of Windows Server 2012 shows an analysis of solutions given by third parties vendors, which offer security products to secure the base system objective of this study. The recommended solution given by the authors present the security vendor Symantec with its successful features and also characteristics that the authors considered that may have to be improved in future versions of the security solution.

Professional SQL Server 2005 administration

CERN Document Server

Knight, Brian; Snyder, Wayne; Armand, Jean-Claude; LoForte, Ross; Ji, Haidong

2007-01-01

SQL Server 2005 is the largest leap forward for SQL Server since its inception. With this update comes new features that will challenge even the most experienced SQL Server DBAs. Written by a team of some of the best SQL Server experts in the industry, this comprehensive tutorial shows you how to navigate the vastly changed landscape of the SQL Server administration. Drawing on their own first-hand experiences to offer you best practices, unique tips and tricks, and useful workarounds, the authors help you handle even the most difficult SQL Server 2005 administration issues, including blockin

QlikView Server and Publisher

CERN Document Server

Redmond, Stephen

2014-01-01

This is a comprehensive guide with a step-by-step approach that enables you to host and manage servers using QlikView Server and QlikView Publisher.If you are a server administrator wanting to learn about how to deploy QlikView Server for server management,analysis and testing, and QlikView Publisher for publishing of business content then this is the perfect book for you. No prior experience with QlikView is expected.

TMFoldWeb: a web server for predicting transmembrane protein fold class.

Science.gov (United States)

Kozma, Dániel; Tusnády, Gábor E

2015-09-17

Here we present TMFoldWeb, the web server implementation of TMFoldRec, a transmembrane protein fold recognition algorithm. TMFoldRec uses statistical potentials and utilizes topology filtering and a gapless threading algorithm. It ranks template structures and selects the most likely candidates and estimates the reliability of the obtained lowest energy model. The statistical potential was developed in a maximum likelihood framework on a representative set of the PDBTM database. According to the benchmark test the performance of TMFoldRec is about 77 % in correctly predicting fold class for a given transmembrane protein sequence. An intuitive web interface has been developed for the recently published TMFoldRec algorithm. The query sequence goes through a pipeline of topology prediction and a systematic sequence to structure alignment (threading). Resulting templates are ordered by energy and reliability values and are colored according to their significance level. Besides the graphical interface, a programmatic access is available as well, via a direct interface for developers or for submitting genome-wide data sets. The TMFoldWeb web server is unique and currently the only web server that is able to predict the fold class of transmembrane proteins while assigning reliability scores for the prediction. This method is prepared for genome-wide analysis with its easy-to-use interface, informative result page and programmatic access. Considering the info-communication evolution in the last few years, the developed web server, as well as the molecule viewer, is responsive and fully compatible with the prevalent tablets and mobile devices.

Web-Beagle: a web server for the alignment of RNA secondary structures.

Science.gov (United States)

Mattei, Eugenio; Pietrosanto, Marco; Ferrè, Fabrizio; Helmer-Citterich, Manuela

2015-07-01

Web-Beagle (http://beagle.bio.uniroma2.it) is a web server for the pairwise global or local alignment of RNA secondary structures. The server exploits a new encoding for RNA secondary structure and a substitution matrix of RNA structural elements to perform RNA structural alignments. The web server allows the user to compute up to 10 000 alignments in a single run, taking as input sets of RNA sequences and structures or primary sequences alone. In the latter case, the server computes the secondary structure prediction for the RNAs on-the-fly using RNAfold (free energy minimization). The user can also compare a set of input RNAs to one of five pre-compiled RNA datasets including lncRNAs and 3' UTRs. All types of comparison produce in output the pairwise alignments along with structural similarity and statistical significance measures for each resulting alignment. A graphical color-coded representation of the alignments allows the user to easily identify structural similarities between RNAs. Web-Beagle can be used for finding structurally related regions in two or more RNAs, for the identification of homologous regions or for functional annotation. Benchmark tests show that Web-Beagle has lower computational complexity, running time and better performances than other available methods. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

Access Control of Web- and Java-Based Applications

Science.gov (United States)

Tso, Kam S.; Pajevski, Michael J.

2013-01-01

Cybersecurity has become a great concern as threats of service interruption, unauthorized access, stealing and altering of information, and spreading of viruses have become more prevalent and serious. Application layer access control of applications is a critical component in the overall security solution that also includes encryption, firewalls, virtual private networks, antivirus, and intrusion detection. An access control solution, based on an open-source access manager augmented with custom software components, was developed to provide protection to both Web-based and Javabased client and server applications. The DISA Security Service (DISA-SS) provides common access control capabilities for AMMOS software applications through a set of application programming interfaces (APIs) and network- accessible security services for authentication, single sign-on, authorization checking, and authorization policy management. The OpenAM access management technology designed for Web applications can be extended to meet the needs of Java thick clients and stand alone servers that are commonly used in the JPL AMMOS environment. The DISA-SS reusable components have greatly reduced the effort for each AMMOS subsystem to develop its own access control strategy. The novelty of this work is that it leverages an open-source access management product that was designed for Webbased applications to provide access control for Java thick clients and Java standalone servers. Thick clients and standalone servers are still commonly used in businesses and government, especially for applications that require rich graphical user interfaces and high-performance visualization that cannot be met by thin clients running on Web browsers

X-Switch: An Efficient , Multi-User, Multi-Language Web Application Server

Directory of Open Access Journals (Sweden)

Mayumbo Nyirenda

2010-07-01

Full Text Available Web applications are usually installed on and accessed through a Web server. For security reasons, these Web servers generally provide very few privileges to Web applications, defaulting to executing them in the realm of a guest ac- count. In addition, performance often is a problem as Web applications may need to be reinitialised with each access. Various solutions have been designed to address these security and performance issues, mostly independently of one another, but most have been language or system-specic. The X-Switch system is proposed as an alternative Web application execution environment, with more secure user-based resource management, persistent application interpreters and support for arbitrary languages/interpreters. Thus it provides a general-purpose environment for developing and deploying Web applications. The X-Switch system's experimental results demonstrated that it can achieve a high level of performance. Further- more it was shown that X-Switch can provide functionality matching that of existing Web application servers but with the added benet of multi-user support. Finally the X-Switch system showed that it is feasible to completely separate the deployment platform from the application code, thus ensuring that the developer does not need to modify his/her code to make it compatible with the deployment platform.

A decade of Web Server updates at the Bioinformatics Links Directory: 2003-2012.

Science.gov (United States)

Brazas, Michelle D; Yim, David; Yeung, Winston; Ouellette, B F Francis

2012-07-01

The 2012 Bioinformatics Links Directory update marks the 10th special Web Server issue from Nucleic Acids Research. Beginning with content from their 2003 publication, the Bioinformatics Links Directory in collaboration with Nucleic Acids Research has compiled and published a comprehensive list of freely accessible, online tools, databases and resource materials for the bioinformatics and life science research communities. The past decade has exhibited significant growth and change in the types of tools, databases and resources being put forth, reflecting both technology changes and the nature of research over that time. With the addition of 90 web server tools and 12 updates from the July 2012 Web Server issue of Nucleic Acids Research, the Bioinformatics Links Directory at http://bioinformatics.ca/links_directory/ now contains an impressive 134 resources, 455 databases and 1205 web server tools, mirroring the continued activity and efforts of our field.

Client-server Approach in the Navigation System for the Blind

Directory of Open Access Journals (Sweden)

Lukasz Markiewicz

2013-09-01

Full Text Available The article presents the client-server approach in the navigation system for the blind - “Voice Maps”. The authors were among the main creators of the prototype and currently the commercialization phase is being finished. In the implemented prototype only exemplary, limited spatial data were used, therefore they could be stored and analyzed (for pathfinding process in the mobile device’s memory without any difficulties. The resulting increase of spatial data scale and complexity required a modification of the data storage and operation. Consequently, the decision was made to maintain a central spatial database, which is accessed remotely. After that modification, the mobile application fetches the required batch of spatial data (with the pathfinding and search results from the central server through the mobile internet connection, which has also become necessary for other purposes (e.g. voice recognition. The authors present the advantages and disadvantages of this new approach along with the results of the server operational tests.

Dataset of Fourier transform-infrared coupled with chemometric analysis used to distinguish accessions of Garcinia mangostana L. in Peninsular Malaysia

OpenAIRE

Samsir, Sri A’jilah; Bunawan, Hamidun; Yen, Choong Chee; Noor, Normah Mohd

2016-01-01

In this dataset, we distinguish 15 accessions of Garcinia mangostana from Peninsular Malaysia using Fourier transform-infrared spectroscopy coupled with chemometric analysis. We found that the position and intensity of characteristic peaks at 3600–3100 cm−1 in IR spectra allowed discrimination of G. mangostana from different locations. Further principal component analysis (PCA) of all the accessions suggests the two main clusters were formed: samples from Johor, Melaka, and Negeri Sembilan (S...

PENGUKURAN KINERJA ROUND-ROBIN SCHEDULER UNTUK LINUX VIRTUAL SERVER PADA KASUS WEB SERVER

Directory of Open Access Journals (Sweden)

Royyana Muslim Ijtihadie

2005-07-01

Full Text Available Normal 0 false false false IN X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} Dengan meningkatnya perkembangan jumlah pengguna internet dan mulai diadopsinya penggunaan internet dalam kehidupan sehari-hari, maka lalulintas data di Internet telah meningkat secara signifikan. Sejalan dengan itu pula beban kerja server-server yang memberikan service di Internet juga mengalami kenaikan yang cukup signifikan. Hal tersebut dapat mengakibatkan suatu server mengalami kelebihan beban pada suatu saat. Untuk mengatasi hal tersebut maka diterapkan skema konfigurasi server cluster menggunakan konsep load balancing. Load balancing server menerapkan algoritma dalam melakukan pembagian tugas. Algoritma round robin telah digunakan pada Linux Virtual Server. Penelitian ini melakukan pengukuran kinerja terhadap Linux Virtual Server yang menggunakan algoritma round robin untuk melakukan penjadwalan pembagian beban terhadap server. Penelitian ini mengukur performa dari sisi client yang mencoba mengakses web server.performa yang diukur adalah jumlah request yang bisa diselesaikan perdetik (request per second, waktu untuk menyelesaikan per satu request, dan   throughput yang dihasilkan. Dari hasil percobaan didapatkan bahwa penggunaan LVS bisa meningkatkan performa, yaitu menaikkan jumlah request per detik

TSKT-ORAM: A Two-Server k-ary Tree Oblivious RAM without Homomorphic Encryption

Directory of Open Access Journals (Sweden)

Jinsheng Zhang

2017-09-01

Full Text Available This paper proposes TSKT-oblivious RAM (ORAM, an efficient multi-server ORAM construction, to protect a client’s access pattern to outsourced data. TSKT-ORAM organizes each of the server storages as a k-ary tree and adopts XOR-based private information retrieval (PIR and a novel delayed eviction technique to optimize both the data query and data eviction process. TSKT-ORAM is proven to protect the data access pattern privacy with a failure probability of 2 - 80 when system parameter k ≥ 128 . Meanwhile, given a constant-size local storage, when N (i.e., the total number of outsourced data blocks ranges from 2 16 – 2 34 , the communication cost of TSKT-ORAM is only 22–46 data blocks. Asymptotic analysis and practical comparisons are conducted to show that TSKT-ORAM incurs lower communication cost, storage cost and access delay in practical scenarios than the compared state-of-the-art ORAM schemes.

Mastering Microsoft Exchange Server 2010

CERN Document Server

McBee, Jim

2010-01-01

A top-selling guide to Exchange Server-now fully updated for Exchange Server 2010. Keep your Microsoft messaging system up to date and protected with the very newest version, Exchange Server 2010, and this comprehensive guide. Whether you're upgrading from Exchange Server 2007 SP1 or earlier, installing for the first time, or migrating from another system, this step-by-step guide provides the hands-on instruction, practical application, and real-world advice you need.: Explains Microsoft Exchange Server 2010, the latest release of Microsoft's messaging system that protects against spam and vir

Analysis of Java Distributed Architectures in Designing and Implementing a Client/Server Database System

National Research Council Canada - National Science Library

Akin, Ramis

1998-01-01

.... Information is scattered throughout organizations and must be easily accessible. A new solution is needed for effective and efficient management of data in today's distributed client/server environment...

Optimal control of a server farm

NARCIS (Netherlands)

Adan, I.J.B.F.; Kulkarni, V.G.; Wijk, van A.C.C.

2013-01-01

We consider a server farm consisting of ample exponential servers, that serve a Poisson stream of arriving customers. Each server can be either busy, idle or off. An arriving customer will immediately occupy an idle server, if there is one, and otherwise, an off server will be turned on and start

NEOS Server 4.0 Administrative Guide

OpenAIRE

Dolan, Elizabeth D.

2001-01-01

The NEOS Server 4.0 provides a general Internet-based client/server as a link between users and software applications. The administrative guide covers the fundamental principals behind the operation of the NEOS Server, installation and trouble-shooting of the Server software, and implementation details of potential interest to a NEOS Server administrator. The guide also discusses making new software applications available through the Server, including areas of concern to remote solver adminis...

Development of a browser application to foster research on linking climate and health datasets: Challenges and opportunities.

Science.gov (United States)

Hajat, Shakoor; Whitmore, Ceri; Sarran, Christophe; Haines, Andy; Golding, Brian; Gordon-Brown, Harriet; Kessel, Anthony; Fleming, Lora E

2017-01-01

Improved data linkages between diverse environment and health datasets have the potential to provide new insights into the health impacts of environmental exposures, including complex climate change processes. Initiatives that link and explore big data in the environment and health arenas are now being established. To encourage advances in this nascent field, this article documents the development of a web browser application to facilitate such future research, the challenges encountered to date, and how they were addressed. A 'storyboard approach' was used to aid the initial design and development of the application. The application followed a 3-tier architecture: a spatial database server for storing and querying data, server-side code for processing and running models, and client-side browser code for user interaction and for displaying data and results. The browser was validated by reproducing previously published results from a regression analysis of time-series datasets of daily mortality, air pollution and temperature in London. Data visualisation and analysis options of the application are presented. The main factors that shaped the development of the browser were: accessibility, open-source software, flexibility, efficiency, user-friendliness, licensing restrictions and data confidentiality, visualisation limitations, cost-effectiveness, and sustainability. Creating dedicated data and analysis resources, such as the one described here, will become an increasingly vital step in improving understanding of the complex interconnections between the environment and human health and wellbeing, whilst still ensuring appropriate confidentiality safeguards. The issues raised in this paper can inform the future development of similar tools by other researchers working in this field. Copyright © 2016 Elsevier B.V. All rights reserved.

National Hydrography Dataset (NHD)

Data.gov (United States)

Kansas Data Access and Support Center — The National Hydrography Dataset (NHD) is a feature-based database that interconnects and uniquely identifies the stream segments or reaches that comprise the...

Development of a high-performance image server using ATM technology

Science.gov (United States)

Do Van, Minh; Humphrey, Louis M.; Ravin, Carl E.

1996-05-01

The ability to display digital radiographs to a radiologist in a reasonable time has long been the goal of many PACS. Intelligent routing, or pre-fetching images, has become a solution whereby a system uses a set of rules to route the images to a pre-determined destination. Images would then be stored locally on a workstation for faster display times. Some PACS use a large, centralized storage approach and workstations retrieve images over high bandwidth connections. Another approach to image management is to provide a high performance, clustered storage system. This has the advantage of eliminating the complexity of pre-fetching and allows for rapid image display from anywhere within the hospital. We discuss the development of such a storage device, which provides extremely fast access to images across a local area network. Among the requirements for development of the image server were high performance, DICOM 3.0 compliance, and the use of industry standard components. The completed image server provides performance more than sufficient for use in clinical practice. Setting up modalities to send images to the image server is simple due to the adherence to the DICOM 3.0 specification. Using only off-the-shelf components allows us to keep the cost of the server relatively inexpensive and allows for easy upgrades as technology becomes more advanced. These factors make the image server ideal for use as a clustered storage system in a radiology department.

Microsoft SQL Server 2012 bible

CERN Document Server

Jorgensen, Adam; LeBlanc, Patrick; Cherry, Denny; Nelson, Aaron

2012-01-01

Harness the powerful new SQL Server 2012 Microsoft SQL Server 2012 is the most significant update to this product since 2005, and it may change how database administrators and developers perform many aspects of their jobs. If you're a database administrator or developer, Microsoft SQL Server 2012 Bible teaches you everything you need to take full advantage of this major release. This detailed guide not only covers all the new features of SQL Server 2012, it also shows you step by step how to develop top-notch SQL Server databases and new data connections and keep your databases performing at p

Windows Home Server users guide

CERN Document Server

Edney, Andrew

2008-01-01

Windows Home Server brings the idea of centralized storage, backup and computer management out of the enterprise and into the home. Windows Home Server is built for people with multiple computers at home and helps to synchronize them, keep them updated, stream media between them, and back them up centrally. Built on a similar foundation as the Microsoft server operating products, it's essentially Small Business Server for the home.This book details how to install, configure, and use Windows Home Server and explains how to connect to and manage different clients such as Windows XP, Windows Vist

Map server of Slovak Environmental Agency

International Nuclear Information System (INIS)

Koska, M.

2005-01-01

The Slovak Environmental Agency (SAZP) is professional organization of the Ministry of Environment of the Slovak Republic. In the area of informatics SAZP is responsible for operation of information system about environment in the Slovak Republic (ISE). The main goal of the ISE is collection, evaluating and accessing of relevant information about environment between organizations of state or administration, public administration, public, scientific institutes etc. SAZP uses technology of publishing of geo-space data so-called WEB maps (dynamic mapping) - maps are formed online. As a technologic part of information system is internet map server

Simulation of Smart Home Activity Datasets

Directory of Open Access Journals (Sweden)

Jonathan Synnott

2015-06-01

Full Text Available A globally ageing population is resulting in an increased prevalence of chronic conditions which affect older adults. Such conditions require long-term care and management to maximize quality of life, placing an increasing strain on healthcare resources. Intelligent environments such as smart homes facilitate long-term monitoring of activities in the home through the use of sensor technology. Access to sensor datasets is necessary for the development of novel activity monitoring and recognition approaches. Access to such datasets is limited due to issues such as sensor cost, availability and deployment time. The use of simulated environments and sensors may address these issues and facilitate the generation of comprehensive datasets. This paper provides a review of existing approaches for the generation of simulated smart home activity datasets, including model-based approaches and interactive approaches which implement virtual sensors, environments and avatars. The paper also provides recommendation for future work in intelligent environment simulation.

Simulation of Smart Home Activity Datasets.

Science.gov (United States)

Synnott, Jonathan; Nugent, Chris; Jeffers, Paul

2015-06-16

A globally ageing population is resulting in an increased prevalence of chronic conditions which affect older adults. Such conditions require long-term care and management to maximize quality of life, placing an increasing strain on healthcare resources. Intelligent environments such as smart homes facilitate long-term monitoring of activities in the home through the use of sensor technology. Access to sensor datasets is necessary for the development of novel activity monitoring and recognition approaches. Access to such datasets is limited due to issues such as sensor cost, availability and deployment time. The use of simulated environments and sensors may address these issues and facilitate the generation of comprehensive datasets. This paper provides a review of existing approaches for the generation of simulated smart home activity datasets, including model-based approaches and interactive approaches which implement virtual sensors, environments and avatars. The paper also provides recommendation for future work in intelligent environment simulation.

Linux Server Security

CERN Document Server

Bauer, Michael D

2005-01-01

Linux consistently appears high up in the list of popular Internet servers, whether it's for the Web, anonymous FTP, or general services such as DNS and delivering mail. But security is the foremost concern of anyone providing such a service. Any server experiences casual probe attempts dozens of time a day, and serious break-in attempts with some frequency as well. This highly regarded book, originally titled Building Secure Servers with Linux, combines practical advice with a firm knowledge of the technical tools needed to ensure security. The book focuses on the most common use of Linux--

NOBAI: a web server for character coding of geometrical and statistical features in RNA structure

Science.gov (United States)

Knudsen, Vegeir; Caetano-Anollés, Gustavo

2008-01-01

The Numeration of Objects in Biology: Alignment Inferences (NOBAI) web server provides a web interface to the applications in the NOBAI software package. This software codes topological and thermodynamic information related to the secondary structure of RNA molecules as multi-state phylogenetic characters, builds character matrices directly in NEXUS format and provides sequence randomization options. The web server is an effective tool that facilitates the search for evolutionary history embedded in the structure of functional RNA molecules. The NOBAI web server is accessible at ‘http://www.manet.uiuc.edu/nobai/nobai.php’. This web site is free and open to all users and there is no login requirement. PMID:18448469

TAPIR, a web server for the prediction of plant microRNA targets, including target mimics.

Science.gov (United States)

Bonnet, Eric; He, Ying; Billiau, Kenny; Van de Peer, Yves

2010-06-15

We present a new web server called TAPIR, designed for the prediction of plant microRNA targets. The server offers the possibility to search for plant miRNA targets using a fast and a precise algorithm. The precise option is much slower but guarantees to find less perfectly paired miRNA-target duplexes. Furthermore, the precise option allows the prediction of target mimics, which are characterized by a miRNA-target duplex having a large loop, making them undetectable by traditional tools. The TAPIR web server can be accessed at: http://bioinformatics.psb.ugent.be/webtools/tapir. Supplementary data are available at Bioinformatics online.

Open client/server computing and middleware

CERN Document Server

Simon, Alan R

2014-01-01

Open Client/Server Computing and Middleware provides a tutorial-oriented overview of open client/server development environments and how client/server computing is being done.This book analyzes an in-depth set of case studies about two different open client/server development environments-Microsoft Windows and UNIX, describing the architectures, various product components, and how these environments interrelate. Topics include the open systems and client/server computing, next-generation client/server architectures, principles of middleware, and overview of ProtoGen+. The ViewPaint environment

An application-layer based centralized information access control for VPN

Institute of Scientific and Technical Information of China (English)

OUYANG Kai; ZHOU Jing-li; XIA Tao; YU Sheng-sheng

2006-01-01

With the rapid development of Virtual Private Network (VPN), many companies and organizations use VPN to implement their private communication. Traditionally, VPN uses security protocols to protect the confidentiality of data, the message integrity and the endpoint authentication. One core technique of VPN is tunneling, by which clients can access the internal servers traversing VPN. However, the tunneling technique also introduces a concealed security hole. It is possible that ifone vicious user can establish tunneling by the VPN server, he can compromise the internal servers behind the VPN server. So this paper presents a novel Application-layer based Centralized Information Access Control (ACIAC) for VPN to solve this problem.To implement an efficient, flexible and multi-decision access control model, we present two key techniques to ACIAC-the centralized management mechanism and the stream-based access control. Firstly, we implement the information center and the constraints/events center for ACIAC. By the two centers, we can provide an abstract access control mechanism, and the material access control can be decided dynamically by the ACIAC's constraint/event mechanism. Then we logically classify the VPN communication traffic into the access stream and the data stream so that we can tightly couple the features of VPN communication with the access control model. We also provide the design of our ACIAC prototype in this paper.

Vfold: a web server for RNA structure and folding thermodynamics prediction.

Science.gov (United States)

Xu, Xiaojun; Zhao, Peinan; Chen, Shi-Jie

2014-01-01

The ever increasing discovery of non-coding RNAs leads to unprecedented demand for the accurate modeling of RNA folding, including the predictions of two-dimensional (base pair) and three-dimensional all-atom structures and folding stabilities. Accurate modeling of RNA structure and stability has far-reaching impact on our understanding of RNA functions in human health and our ability to design RNA-based therapeutic strategies. The Vfold server offers a web interface to predict (a) RNA two-dimensional structure from the nucleotide sequence, (b) three-dimensional structure from the two-dimensional structure and the sequence, and (c) folding thermodynamics (heat capacity melting curve) from the sequence. To predict the two-dimensional structure (base pairs), the server generates an ensemble of structures, including loop structures with the different intra-loop mismatches, and evaluates the free energies using the experimental parameters for the base stacks and the loop entropy parameters given by a coarse-grained RNA folding model (the Vfold model) for the loops. To predict the three-dimensional structure, the server assembles the motif scaffolds using structure templates extracted from the known PDB structures and refines the structure using all-atom energy minimization. The Vfold-based web server provides a user friendly tool for the prediction of RNA structure and stability. The web server and the source codes are freely accessible for public use at "http://rna.physics.missouri.edu".

Windows server cookbook for Windows server 2003 and Windows 2000

CERN Document Server

Allen, Robbie

2005-01-01

This practical reference guide offers hundreds of useful tasks for managing Windows 2000 and Windows Server 2003, Microsoft's latest server. These concise, on-the-job solutions to common problems are certain to save you many hours of time searching through Microsoft documentation. Topics include files, event logs, security, DHCP, DNS, backup/restore, and more

Learning SQL Server Reporting Services 2012

CERN Document Server

Krishnaswamy, Jayaram

2013-01-01

The book is packed with clear instructions and plenty of screenshots, providing all the support and guidance you will need as you begin to generate reports with SQL Server 2012 Reporting Services.This book is for those who are new to SQL Server Reporting Services 2012 and aspiring to create and deploy cutting edge reports. This book is for report developers, report authors, ad-hoc report authors and model developers, and Report Server and SharePoint Server Integrated Report Server administrators. Minimal knowledge of SQL Server is assumed and SharePoint experience would be helpful.

A Faster Parallel Algorithm and Efficient Multithreaded Implementations for Evaluating Betweenness Centrality on Massive Datasets

Energy Technology Data Exchange (ETDEWEB)

Madduri, Kamesh; Ediger, David; Jiang, Karl; Bader, David A.; Chavarria-Miranda, Daniel

2009-02-15

We present a new lock-free parallel algorithm for computing betweenness centralityof massive small-world networks. With minor changes to the data structures, ouralgorithm also achieves better spatial cache locality compared to previous approaches. Betweenness centrality is a key algorithm kernel in HPCS SSCA#2, a benchmark extensively used to evaluate the performance of emerging high-performance computing architectures for graph-theoretic computations. We design optimized implementations of betweenness centrality and the SSCA#2 benchmark for two hardware multithreaded systems: a Cray XMT system with the Threadstorm processor, and a single-socket Sun multicore server with the UltraSPARC T2 processor. For a small-world network of 134 million vertices and 1.073 billion edges, the 16-processor XMT system and the 8-core Sun Fire T5120 server achieve TEPS scores (an algorithmic performance count for the SSCA#2 benchmark) of 160 million and 90 million respectively, which corresponds to more than a 2X performance improvement over the previous parallel implementations. To better characterize the performance of these multithreaded systems, we correlate the SSCA#2 performance results with data from the memory-intensive STREAM and RandomAccess benchmarks. Finally, we demonstrate the applicability of our implementation to analyze massive real-world datasets by computing approximate betweenness centrality for a large-scale IMDb movie-actor network.

The MetaLex Document Server : Legal Documents as Versioned Linked Data

NARCIS (Netherlands)

Hoekstra, R.; Aroyo, L.; Welty, C.; Alani, H.; Taylor, J.; Bernstein, A.; Kagal, L.; Noy, N.; Blomqvist, E.

2011-01-01

This paper introduces the MetaLex Document Server (MDS), an ongoing project to improve access to legal sources (regulations, court rulings) by means of a generic legal XML syntax (CEN MetaLex) and Linked Data. The MDS defines a generic conversion mechanism from legacy legal XML syntaxes to CEN

Isfahan MISP Dataset.

Science.gov (United States)

Kashefpur, Masoud; Kafieh, Rahele; Jorjandi, Sahar; Golmohammadi, Hadis; Khodabande, Zahra; Abbasi, Mohammadreza; Teifuri, Nilufar; Fakharzadeh, Ali Akbar; Kashefpoor, Maryam; Rabbani, Hossein

2017-01-01

An online depository was introduced to share clinical ground truth with the public and provide open access for researchers to evaluate their computer-aided algorithms. PHP was used for web programming and MySQL for database managing. The website was entitled "biosigdata.com." It was a fast, secure, and easy-to-use online database for medical signals and images. Freely registered users could download the datasets and could also share their own supplementary materials while maintaining their privacies (citation and fee). Commenting was also available for all datasets, and automatic sitemap and semi-automatic SEO indexing have been set for the site. A comprehensive list of available websites for medical datasets is also presented as a Supplementary (http://journalonweb.com/tempaccess/4800.584.JMSS_55_16I3253.pdf).

VisIVO: A Library and Integrated Tools for Large Astrophysical Dataset Exploration

Science.gov (United States)

Becciani, U.; Costa, A.; Ersotelos, N.; Krokos, M.; Massimino, P.; Petta, C.; Vitello, F.

2012-09-01

VisIVO provides an integrated suite of tools and services that can be used in many scientific fields. VisIVO development starts in the Virtual Observatory framework. VisIVO allows users to visualize meaningfully highly-complex, large-scale datasets and create movies of these visualizations based on distributed infrastructures. VisIVO supports high-performance, multi-dimensional visualization of large-scale astrophysical datasets. Users can rapidly obtain meaningful visualizations while preserving full and intuitive control of the relevant parameters. VisIVO consists of VisIVO Desktop - a stand-alone application for interactive visualization on standard PCs, VisIVO Server - a platform for high performance visualization, VisIVO Web - a custom designed web portal, VisIVOSmartphone - an application to exploit the VisIVO Server functionality and the latest VisIVO features: VisIVO Library allows a job running on a computational system (grid, HPC, etc.) to produce movies directly with the code internal data arrays without the need to produce intermediate files. This is particularly important when running on large computational facilities, where the user wants to have a look at the results during the data production phase. For example, in grid computing facilities, images can be produced directly in the grid catalogue while the user code is running in a system that cannot be directly accessed by the user (a worker node). The deployment of VisIVO on the DG and gLite is carried out with the support of EDGI and EGI-Inspire projects. Depending on the structure and size of datasets under consideration, the data exploration process could take several hours of CPU for creating customized views and the production of movies could potentially last several days. For this reason an MPI parallel version of VisIVO could play a fundamental role in increasing performance, e.g. it could be automatically deployed on nodes that are MPI aware. A central concept in our development is thus to

Beginning Microsoft SQL Server 2012 Programming

CERN Document Server

Atkinson, Paul

2012-01-01

Get up to speed on the extensive changes to the newest release of Microsoft SQL Server The 2012 release of Microsoft SQL Server changes how you develop applications for SQL Server. With this comprehensive resource, SQL Server authority Robert Vieira presents the fundamentals of database design and SQL concepts, and then shows you how to apply these concepts using the updated SQL Server. Publishing time and date with the 2012 release, Beginning Microsoft SQL Server 2012 Programming begins with a quick overview of database design basics and the SQL query language and then quickly proceeds to sho

The eDoc-Server Project Building an Institutional Repository for the Max Planck Society

CERN Document Server

Beier, Gerhard

2004-01-01

With the eDoc-Server the Heinz Nixdorf Center for Information Management in the Max Planck Society (ZIM) provides the research institutes of the Max Planck Society (MPS) with a platform to disseminate, store, and manage their scientific output. Moreover, eDoc serves as a tool to facilitate and promote open access to scientific information and primary sources. Since its introduction in October 2002 eDoc has gained high visibility within the MPS. It has been backed by strong institutional commitment to open access as documented in the 'Berlin Declaration on Open Access to the Data of the Sciences and Humanities', which was initiated by the MPS and found large support among major research organizations in Europe. This paper will outline the concept as well as the current status of the eDoc-Server, providing an example for the development and introduction of an institutional repository in a multi-disciplinary research organization.

Barcode server: a visualization-based genome analysis system.

Directory of Open Access Journals (Sweden)

Fenglou Mao

Full Text Available We have previously developed a computational method for representing a genome as a barcode image, which makes various genomic features visually apparent. We have demonstrated that this visual capability has made some challenging genome analysis problems relatively easy to solve. We have applied this capability to a number of challenging problems, including (a identification of horizontally transferred genes, (b identification of genomic islands with special properties and (c binning of metagenomic sequences, and achieved highly encouraging results. These application results inspired us to develop this barcode-based genome analysis server for public service, which supports the following capabilities: (a calculation of the k-mer based barcode image for a provided DNA sequence; (b detection of sequence fragments in a given genome with distinct barcodes from those of the majority of the genome, (c clustering of provided DNA sequences into groups having similar barcodes; and (d homology-based search using Blast against a genome database for any selected genomic regions deemed to have interesting barcodes. The barcode server provides a job management capability, allowing processing of a large number of analysis jobs for barcode-based comparative genome analyses. The barcode server is accessible at http://csbl1.bmb.uga.edu/Barcode.

A robust cloud access scheme with mutual authentication

Directory of Open Access Journals (Sweden)

Chen Chin-Ling

2016-01-01

Full Text Available Due to the progress of network technology, we can access some information through remote servers, and we also can save and access lots of personal data in remote servers. Therefore, to protect these data and resist unauthorized access is an important issue. Some researchers proposed authentication scheme, but there still exist some security weaknesses. This article is based on the concept of HDFS (Hadoop Distributed File System, and offers a robust authentication scheme. The proposed scheme achieves mutual authentication, prevents re-play attack, solves asynchronous issue, and prevents offline password guessing attack.

Catalytic site identification—a web server to identify catalytic site structural matches throughout PDB

Science.gov (United States)

Kirshner, Daniel A.; Nilmeier, Jerome P.; Lightstone, Felice C.

2013-01-01

The catalytic site identification web server provides the innovative capability to find structural matches to a user-specified catalytic site among all Protein Data Bank proteins rapidly (in less than a minute). The server also can examine a user-specified protein structure or model to identify structural matches to a library of catalytic sites. Finally, the server provides a database of pre-calculated matches between all Protein Data Bank proteins and the library of catalytic sites. The database has been used to derive a set of hypothesized novel enzymatic function annotations. In all cases, matches and putative binding sites (protein structure and surfaces) can be visualized interactively online. The website can be accessed at http://catsid.llnl.gov. PMID:23680785

SPEER-SERVER: a web server for prediction of protein specificity determining sites.

Science.gov (United States)

Chakraborty, Abhijit; Mandloi, Sapan; Lanczycki, Christopher J; Panchenko, Anna R; Chakrabarti, Saikat

2012-07-01

Sites that show specific conservation patterns within subsets of proteins in a protein family are likely to be involved in the development of functional specificity. These sites, generally termed specificity determining sites (SDS), might play a crucial role in binding to a specific substrate or proteins. Identification of SDS through experimental techniques is a slow, difficult and tedious job. Hence, it is very important to develop efficient computational methods that can more expediently identify SDS. Herein, we present Specificity prediction using amino acids' Properties, Entropy and Evolution Rate (SPEER)-SERVER, a web server that predicts SDS by analyzing quantitative measures of the conservation patterns of protein sites based on their physico-chemical properties and the heterogeneity of evolutionary changes between and within the protein subfamilies. This web server provides an improved representation of results, adds useful input and output options and integrates a wide range of analysis and data visualization tools when compared with the original standalone version of the SPEER algorithm. Extensive benchmarking finds that SPEER-SERVER exhibits sensitivity and precision performance that, on average, meets or exceeds that of other currently available methods. SPEER-SERVER is available at http://www.hpppi.iicb.res.in/ss/.

ngLOC: software and web server for predicting protein subcellular localization in prokaryotes and eukaryotes

Directory of Open Access Journals (Sweden)

King Brian R

2012-07-01

Full Text Available Abstract Background Understanding protein subcellular localization is a necessary component toward understanding the overall function of a protein. Numerous computational methods have been published over the past decade, with varying degrees of success. Despite the large number of published methods in this area, only a small fraction of them are available for researchers to use in their own studies. Of those that are available, many are limited by predicting only a small number of organelles in the cell. Additionally, the majority of methods predict only a single location for a sequence, even though it is known that a large fraction of the proteins in eukaryotic species shuttle between locations to carry out their function. Findings We present a software package and a web server for predicting the subcellular localization of protein sequences based on the ngLOC method. ngLOC is an n-gram-based Bayesian classifier that predicts subcellular localization of proteins both in prokaryotes and eukaryotes. The overall prediction accuracy varies from 89.8% to 91.4% across species. This program can predict 11 distinct locations each in plant and animal species. ngLOC also predicts 4 and 5 distinct locations on gram-positive and gram-negative bacterial datasets, respectively. Conclusions ngLOC is a generic method that can be trained by data from a variety of species or classes for predicting protein subcellular localization. The standalone software is freely available for academic use under GNU GPL, and the ngLOC web server is also accessible at http://ngloc.unmc.edu.

Mastering Microsoft Exchange Server 2013

CERN Document Server

Elfassy, David

2013-01-01

The bestselling guide to Exchange Server, fully updated for the newest version Microsoft Exchange Server 2013 is touted as a solution for lowering the total cost of ownership, whether deployed on-premises or in the cloud. Like the earlier editions, this comprehensive guide covers every aspect of installing, configuring, and managing this multifaceted collaboration system. It offers Windows systems administrators and consultants a complete tutorial and reference, ideal for anyone installing Exchange Server for the first time or those migrating from an earlier Exchange Server version.Microsoft

Remote access to mathematical software

International Nuclear Information System (INIS)

Dolan, E.; Hovland, P.; More, J.; Norris, B.; Smith, B.

2001-01-01

The network-oriented application services paradigm is becoming increasingly common for scientific computing. The popularity of this approach can be attributed to the numerous advantages to both user and developer provided by network-enabled mathematical software. The burden of installing and maintaining complex systems is lifted from the user, while enabling developers to provide frequent updates without disrupting service. Access to software with similar functionality can be unified under the same interface. Remote servers can utilize potentially more powerful computing resources than may be available locally. We discuss some of the application services developed by the Mathematics and Computer Science Division at Argonne National Laboratory, including the Network Enabled Optimization System (NEOS) Server and the Automatic Differentiation of C (ADIC) Server, as well as preliminary work on Web access to the Portable Extensible Toolkit for Scientific Computing (PETSc). We also provide a brief survey of related work

The Case for Adopting Server-side Analytics

Science.gov (United States)

Tino, C.; Holmes, C. P.; Feigelson, E.; Hurlburt, N. E.

2017-12-01

The standard method for accessing Earth and space science data relies on a scheme developed decades ago: data residing in one or many data stores must be parsed out and shipped via internet lines or physical transport to the researcher who in turn locally stores the data for analysis. The analyses tasks are varied and include visualization, parameterization, and comparison with or assimilation into physics models. In many cases this process is inefficient and unwieldy as the data sets become larger and demands on the analysis tasks become more sophisticated and complex. For about a decade, several groups have explored a new paradigm to this model. The names applied to the paradigm include "data analytics", "climate analytics", and "server-side analytics". The general concept is that in close network proximity to the data store there will be a tailored processing capability appropriate to the type and use of the data served. The user of the server-side analytics will operate on the data with numerical procedures. The procedures can be accessed via canned code, a scripting processor, or an analysis package such as Matlab, IDL or R. Results of the analytics processes will then be relayed via the internet to the user. In practice, these results will be at a much lower volume, easier to transport to and store locally by the user and easier for the user to interoperate with data sets from other remote data stores. The user can also iterate on the processing call to tailor the results as needed. A major component of server-side analytics could be to provide sets of tailored results to end users in order to eliminate the repetitive preconditioning that is both often required with these data sets and which drives much of the throughput challenges. NASA's Big Data Task Force studied this issue. This paper will present the results of this study including examples of SSAs that are being developed and demonstrated and suggestions for architectures that might be developed for

Exam 70-411 administering Windows Server 2012

CERN Document Server

Course, Microsoft Official Academic

2014-01-01

Microsoft Windows Server is a multi-purpose server designed to increase reliability and flexibility of  a network infrastructure. Windows Server is the paramount tool used by enterprises in their datacenter and desktop strategy. The most recent versions of Windows Server also provide both server and client virtualization. Its ubiquity in the enterprise results in the need for networking professionals who know how to plan, design, implement, operate, and troubleshoot networks relying on Windows Server. Microsoft Learning is preparing the next round of its Windows Server Certification program

Pro SQL Server 2008 Analysis Services

CERN Document Server

Janus, Philo B

2009-01-01

Every business has a reams of business data locked away in databases, business systems, and spreadsheets. While you may be able to build some reports by pulling a few of these repositories together, actually performing any kind of analysis on the data that runs your business can range from problematic to impossible. Pro SQL Server 2008 Analysis Services will show you how to pull that data together and present it for reporting and analysis in a way that makes the data accessible to business users, instead of needing to rely on the IT department every time someone needs a different report. * Acc

ORCAN-a web-based meta-server for real-time detection and functional annotation of orthologs.

Science.gov (United States)

Zielezinski, Andrzej; Dziubek, Michal; Sliski, Jan; Karlowski, Wojciech M

2017-04-15

ORCAN (ORtholog sCANner) is a web-based meta-server for one-click evolutionary and functional annotation of protein sequences. The server combines information from the most popular orthology-prediction resources, including four tools and four online databases. Functional annotation utilizes five additional comparisons between the query and identified homologs, including: sequence similarity, protein domain architectures, functional motifs, Gene Ontology term assignments and a list of associated articles. Furthermore, the server uses a plurality-based rating system to evaluate the orthology relationships and to rank the reference proteins by their evolutionary and functional relevance to the query. Using a dataset of ∼1 million true yeast orthologs as a sample reference set, we show that combining multiple orthology-prediction tools in ORCAN increases the sensitivity and precision by 1-2 percent points. The service is available for free at http://www.combio.pl/orcan/ . wmk@amu.edu.pl. Supplementary data are available at Bioinformatics online. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

The web server of IBM's Bioinformatics and Pattern Discovery group: 2004 update.

Science.gov (United States)

Huynh, Tien; Rigoutsos, Isidore

2004-07-01

In this report, we provide an update on the services and content which are available on the web server of IBM's Bioinformatics and Pattern Discovery group. The server, which is operational around the clock, provides access to a large number of methods that have been developed and published by the group's members. There is an increasing number of problems that these tools can help tackle; these problems range from the discovery of patterns in streams of events and the computation of multiple sequence alignments, to the discovery of genes in nucleic acid sequences, the identification--directly from sequence--of structural deviations from alpha-helicity and the annotation of amino acid sequences for antimicrobial activity. Additionally, annotations for more than 130 archaeal, bacterial, eukaryotic and viral genomes are now available on-line and can be searched interactively. The tools and code bundles continue to be accessible from http://cbcsrv.watson.ibm.com/Tspd.html whereas the genomics annotations are available at http://cbcsrv.watson.ibm.com/Annotations/.

DMINDA: an integrated web server for DNA motif identification and analyses.

Science.gov (United States)

Ma, Qin; Zhang, Hanyuan; Mao, Xizeng; Zhou, Chuan; Liu, Bingqiang; Chen, Xin; Xu, Ying

2014-07-01

DMINDA (DNA motif identification and analyses) is an integrated web server for DNA motif identification and analyses, which is accessible at http://csbl.bmb.uga.edu/DMINDA/. This web site is freely available to all users and there is no login requirement. This server provides a suite of cis-regulatory motif analysis functions on DNA sequences, which are important to elucidation of the mechanisms of transcriptional regulation: (i) de novo motif finding for a given set of promoter sequences along with statistical scores for the predicted motifs derived based on information extracted from a control set, (ii) scanning motif instances of a query motif in provided genomic sequences, (iii) motif comparison and clustering of identified motifs, and (iv) co-occurrence analyses of query motifs in given promoter sequences. The server is powered by a backend computer cluster with over 150 computing nodes, and is particularly useful for motif prediction and analyses in prokaryotic genomes. We believe that DMINDA, as a new and comprehensive web server for cis-regulatory motif finding and analyses, will benefit the genomic research community in general and prokaryotic genome researchers in particular. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

PRince: a web server for structural and physicochemical analysis of protein-RNA interface.

Science.gov (United States)

Barik, Amita; Mishra, Abhishek; Bahadur, Ranjit Prasad

2012-07-01

We have developed a web server, PRince, which analyzes the structural features and physicochemical properties of the protein-RNA interface. Users need to submit a PDB file containing the atomic coordinates of both the protein and the RNA molecules in complex form (in '.pdb' format). They should also mention the chain identifiers of interacting protein and RNA molecules. The size of the protein-RNA interface is estimated by measuring the solvent accessible surface area buried in contact. For a given protein-RNA complex, PRince calculates structural, physicochemical and hydration properties of the interacting surfaces. All these parameters generated by the server are presented in a tabular format. The interacting surfaces can also be visualized with software plug-in like Jmol. In addition, the output files containing the list of the atomic coordinates of the interacting protein, RNA and interface water molecules can be downloaded. The parameters generated by PRince are novel, and users can correlate them with the experimentally determined biophysical and biochemical parameters for better understanding the specificity of the protein-RNA recognition process. This server will be continuously upgraded to include more parameters. PRince is publicly accessible and free for use. Available at http://www.facweb.iitkgp.ernet.in/~rbahadur/prince/home.html.

Mac OS X Lion Server For Dummies

CERN Document Server

Rizzo, John

2011-01-01

The perfect guide to help administrators set up Apple's Mac OS X Lion Server With the overwhelming popularity of the iPhone and iPad, more Macs are appearing in corporate settings. The newest version of Mac Server is the ideal way to administer a Mac network. This friendly guide explains to both Windows and Mac administrators how to set up and configure the server, including services such as iCal Server, Podcast Producer, Wiki Server, Spotlight Server, iChat Server, File Sharing, Mail Services, and support for iPhone and iPad. It explains how to secure, administer, and troubleshoot the networ

Learning Zimbra Server essentials

CERN Document Server

Kouka, Abdelmonam

2013-01-01

A standard tutorial approach which will guide the readers on all of the intricacies of the Zimbra Server.If you are any kind of Zimbra user, this book will be useful for you, from newbies to experts who would like to learn how to setup a Zimbra server. If you are an IT administrator or consultant who is exploring the idea of adopting, or have already adopted Zimbra as your mail server, then this book is for you. No prior knowledge of Zimbra is required.

MCSA Windows Server 2012 R2 configuring advanced services study guide exam 70-412

CERN Document Server

Panek, William

2015-01-01

The bestselling MCSA study guide, with expert instruction andhands-on practice MCSA Windows Server 2012 R2 Configuring Advanced ServicesStudy Guide provides focused preparation for exam 70-412 and isfully updated to align with the latest Windows Server 2012 R2objectives. This comprehensive guide covers 100 percent of all examobjective domains, and includes hundreds of practice questions andanswers. You get access to video demonstrations, electronicflashcards, and practice exams, and hands-on exercises based onreal-world scenarios allow you to apply your skills to everydaytasks. Organized by o

Microsoft Windows Server Administration Essentials

CERN Document Server

Carpenter, Tom

2011-01-01

The core concepts and technologies you need to administer a Windows Server OS Administering a Windows operating system (OS) can be a difficult topic to grasp, particularly if you are new to the field of IT. This full-color resource serves as an approachable introduction to understanding how to install a server, the various roles of a server, and how server performance and maintenance impacts a network. With a special focus placed on the new Microsoft Technology Associate (MTA) certificate, the straightforward, easy-to-understand tone is ideal for anyone new to computer administration looking t

GeoServer: il server geospaziale Open Source novità della nuova versione 2.3.0

Directory of Open Access Journals (Sweden)

Simone Giannecchini

2013-04-01

Full Text Available GeoServer è un server geospaziale Open Source sviluppato con tecnologia Java Enterprise per la gestione e l’editing di dati geospaziali secondo gli standard OGC e ISO Technical Committee 211. Esso fornisce le funzionalità di base per creareinfrastrutture spaziali di dati (SDI ed è progettato per essere interoperabile potendo pubblicare dati provenienti da ogni tipo di fonte spaziale utilizzando standard aperti.Open Source GeoSpatial server developed with Java Enterprise technology for managing, sharing and editing geospatial data according to the OGC and ISO TC 211 standards. GeoServer provides the basic functionalities to create spatial data infrastructures (SDI.GeoServer is designed for interoperability, it publishes data from any major spatial data source using open standards: it is the reference implementation of the Open Geospatial Consortium (OGC Web Feature Service (WFS and Web Coverage Service (WCS standards, as well as a highperformance certified compliant Web Map Service (WMS. GeoServer forms a core component of the Geospatial Web.

Medical video server construction.

Science.gov (United States)

Dańda, Jacek; Juszkiewicz, Krzysztof; Leszczuk, Mikołaj; Loziak, Krzysztof; Papir, Zdzisław; Sikora, Marek; Watza, Rafal

2003-01-01

The paper discusses two implementation options for a Digital Video Library, a repository used for archiving, accessing, and browsing of video medical records. Two crucial issues to be decided on are a video compression format and a video streaming platform. The paper presents numerous decision factors that have to be taken into account. The compression formats being compared are DICOM as a format representative for medical applications, both MPEGs, and several new formats targeted for an IP networking. The comparison includes transmission rates supported, compression rates, and at least options for controlling a compression process. The second part of the paper presents the ISDN technique as a solution for provisioning of tele-consultation services between medical parties that are accessing resources uploaded to a digital video library. There are several backbone techniques (like corporate LANs/WANs, leased lines or even radio/satellite links) available, however, the availability of network resources for hospitals was the prevailing choice criterion pointing to ISDN solutions. Another way to provide access to the Digital Video Library is based on radio frequency domain solutions. The paper describes possibilities of both, wireless and cellular network's data transmission service to be used as a medical video server transport layer. For the cellular net-work based solution two communication techniques are used: Circuit Switched Data and Packet Switched Data.

NEW WEB-BASED ACCESS TO NUCLEAR STRUCTURE DATASETS.

Energy Technology Data Exchange (ETDEWEB)

WINCHELL,D.F.

2004-09-26

As part of an effort to migrate the National Nuclear Data Center (NNDC) databases to a relational platform, a new web interface has been developed for the dissemination of the nuclear structure datasets stored in the Evaluated Nuclear Structure Data File and Experimental Unevaluated Nuclear Data List.

User guide to JINR server of scientific publications JDS

International Nuclear Information System (INIS)

Filozova, I.A.; Zaikina, T.N.; Musul'manbekov, Zh.Zh.; Semenov, R.N.; Shestakova, G.V.

2011-01-01

In the framework of the international program OAI (Open Access Initiative) the digital open access archive-repository JINR Document Server (JDS) is built up. The main goal of the JDS is to collect at the JINR site all the publications of JINR researchers. The documents deposited in the repository are preprints, journal articles, books, conference papers, conference announcements, theses, annual reports, etc. Currently, the retrospective publications of JINR authors up to 1956 are deposited. The JDS, being an integrated digital library system, gives users an opportunity to deposit manuscripts in self-archiving mode, create personal catalogs, subscribe to alerts and RSS, send comments and arrange discussions on submitted papers

Professional Microsoft SQL Server 2012 Administration

CERN Document Server

Jorgensen, Adam; LoForte, Ross; Knight, Brian

2012-01-01

An essential how-to guide for experienced DBAs on the most significant product release since 2005! Microsoft SQL Server 2012 will have major changes throughout the SQL Server and will impact how DBAs administer the database. With this book, a team of well-known SQL Server experts introduces the many new features of the most recent version of SQL Server and deciphers how these changes will affect the methods that administrators have been using for years. Loaded with unique tips, tricks, and workarounds for handling the most difficult SQL Server admin issues, this how-to guide deciphers topics s

Essential Mac OS X panther server administration integrating Mac OS X server into heterogeneous networks

CERN Document Server

Bartosh, Michael

2004-01-01

If you've ever wondered how to safely manipulate Mac OS X Panther Server's many underlying configuration files or needed to explain AFP permission mapping--this book's for you. From the command line to Apple's graphical tools, the book provides insight into this powerful server software. Topics covered include installation, deployment, server management, web application services, data gathering, and more

The PARIGA server for real time filtering and analysis of reciprocal BLAST results.

Directory of Open Access Journals (Sweden)

Massimiliano Orsini

Full Text Available BLAST-based similarity searches are commonly used in several applications involving both nucleotide and protein sequences. These applications span from simple tasks such as mapping sequences over a database to more complex procedures as clustering or annotation processes. When the amount of analysed data increases, manual inspection of BLAST results become a tedious procedure. Tools for parsing or filtering BLAST results for different purposes are then required. We describe here PARIGA (http://resources.bioinformatica.crs4.it/pariga/, a server that enables users to perform all-against-all BLAST searches on two sets of sequences selected by the user. Moreover, since it stores the two BLAST output in a python-serialized-objects database, results can be filtered according to several parameters in real-time fashion, without re-running the process and avoiding additional programming efforts. Results can be interrogated by the user using logical operations, for example to retrieve cases where two queries match same targets, or when sequences from the two datasets are reciprocal best hits, or when a query matches a target in multiple regions. The Pariga web server is designed to be a helpful tool for managing the results of sequence similarity searches. The design and implementation of the server renders all operations very fast and easy to use.

Access 2010 Programmer's Reference

CERN Document Server

Hennig, Teresa; Griffith, Geoffrey L

2010-01-01

A comprehensive guide to programming for Access 2010 and 2007. Millions of people use the Access database applications, and hundreds of thousands of developers work with Access daily. Access 2010 brings better integration with SQL Server and enhanced XML support; this Wrox guide shows developers how to take advantage of these and other improvements. With in-depth coverage of VBA, macros, and other programming methods for building Access applications, this book also provides real-world code examples to demonstrate each topic.: Access is the leading database that is used worldwide; While VBA rem

Network characteristics for server selection in online games

Science.gov (United States)

Claypool, Mark

2008-01-01

Online gameplay is impacted by the network characteristics of players connected to the same server. Unfortunately, the network characteristics of online game servers are not well-understood, particularly for groups that wish to play together on the same server. As a step towards a remedy, this paper presents analysis of an extensive set of measurements of game servers on the Internet. Over the course of many months, actual Internet game servers were queried simultaneously by twenty-five emulated game clients, with both servers and clients spread out on the Internet. The data provides statistics on the uptime and populations of game servers over a month long period an an in-depth look at the suitability for game servers for multi-player server selection, concentrating on characteristics critical to playability--latency and fairness. Analysis finds most game servers have latencies suitable for third-person and omnipresent games, such as real-time strategy, sports and role-playing games, providing numerous server choices for game players. However, far fewer game servers have the low latencies required for first-person games, such as shooters or race games. In all cases, groups that wish to play together have a greatly reduced set of servers from which to choose because of inherent unfairness in server latencies and server selection is particularly limited as the group size increases. These results hold across different game types and even across different generations of games. The data should be useful for game developers and network researchers that seek to improve game server selection, whether for single or multiple players.

Dataset of Fourier transform-infrared coupled with chemometric analysis used to distinguish accessions of Garcinia mangostana L. in Peninsular Malaysia.

Science.gov (United States)

Samsir, Sri A'jilah; Bunawan, Hamidun; Yen, Choong Chee; Noor, Normah Mohd

2016-09-01

In this dataset, we distinguish 15 accessions of Garcinia mangostana from Peninsular Malaysia using Fourier transform-infrared spectroscopy coupled with chemometric analysis. We found that the position and intensity of characteristic peaks at 3600-3100 cm(-) (1) in IR spectra allowed discrimination of G. mangostana from different locations. Further principal component analysis (PCA) of all the accessions suggests the two main clusters were formed: samples from Johor, Melaka, and Negeri Sembilan (South) were clustered together in one group while samples from Perak, Kedah, Penang, Selangor, Kelantan, and Terengganu (North and East Coast) were in another clustered group.

ProBiS-2012: web server and web services for detection of structurally similar binding sites in proteins.

Science.gov (United States)

Konc, Janez; Janezic, Dusanka

2012-07-01

The ProBiS web server is a web server for detection of structurally similar binding sites in the PDB and for local pairwise alignment of protein structures. In this article, we present a new version of the ProBiS web server that is 10 times faster than earlier versions, due to the efficient parallelization of the ProBiS algorithm, which now allows significantly faster comparison of a protein query against the PDB and reduces the calculation time for scanning the entire PDB from hours to minutes. It also features new web services, and an improved user interface. In addition, the new web server is united with the ProBiS-Database and thus provides instant access to pre-calculated protein similarity profiles for over 29 000 non-redundant protein structures. The ProBiS web server is particularly adept at detection of secondary binding sites in proteins. It is freely available at http://probis.cmm.ki.si/old-version, and the new ProBiS web server is at http://probis.cmm.ki.si.

OPC Server and BridgeView Application for High Voltage Power Supply Lecroy 1458

CERN Document Server

Swoboda, D; CERN. Geneva

2000-01-01

Abstract The aim of this project was to develop an OPC server to communicate over an RS232 serial line. This communication media is commonly used with commercial instruments. The development was made for a High Voltage power supply in the context of the Alice [1] experiment. In addition, the structured modular concept will allow changing the transmission media or power supply type with little effort. The high voltage power supply should be accessible remotely through a network. OPC[2] is an acronym for OLE[3] for Process Control. OPC is based on the DCOM [3] communication protocol, which allows communication with any computer running a Windows based OS. This standard is widely used in industry to access device data through Windows applications. The concept is based on the client-server architecture. The hardware and the software architecture are described. Subsequently details of the implemented programs are given with emphasis on the possibility to replace parts of the software in order to use differ...

Secure data aggregation in heterogeneous and disparate networks using stand off server architecture

Science.gov (United States)

Vimalathithan, S.; Sudarsan, S. D.; Seker, R.; Lenin, R. B.; Ramaswamy, S.

2009-04-01

The emerging global reach of technology presents myriad challenges and intricacies as Information Technology teams aim to provide anywhere, anytime and anyone access, for service providers and customers alike. The world is fraught with stifling inequalities, both from an economic as well as socio-political perspective. The net result has been large capability gaps between various organizational locations that need to work together, which has raised new challenges for information security teams. Similar issues arise, when mergers and acquisitions among and between organizations take place. While integrating remote business locations with mainstream operations, one or more of the issues including the lack of application level support, computational capabilities, communication limitations, and legal requirements cause a serious impediment thereby complicating integration while not violating the organizations' security requirements. Often resorted techniques like IPSec, tunneling, secure socket layer, etc. may not be always techno-economically feasible. This paper addresses such security issues by introducing an intermediate server between corporate central server and remote sites, called stand-off-server. We present techniques such as break-before-make connection, break connection after transfer, multiple virtual machine instances with different operating systems using the concept of a stand-off-server. Our experiments show that the proposed solution provides sufficient isolation for the central server/site from attacks arising out of weak communication and/or computing links and is simple to implement.

Object oriented programming techniques applied to device access and control

International Nuclear Information System (INIS)

Goetz, A.; Klotz, W.D.; Meyer, J.

1992-01-01

In this paper a model, called the device server model, has been presented for solving the problem of device access and control faced by all control systems. Object Oriented Programming techniques were used to achieve a powerful yet flexible solution. The model provides a solution to the problem which hides device dependancies. It defines a software framework which has to be respected by implementors of device classes - this is very useful for developing groupware. The decision to implement remote access in the root class means that device servers can be easily integrated in a distributed control system. A lot of the advantages and features of the device server model are due to the adoption of OOP techniques. The main conclusion that can be drawn from this paper is that 1. the device access and control problem is adapted to being solved with OOP techniques, 2. OOP techniques offer a distinct advantage over traditional programming techniques for solving the device access problem. (J.P.N.)

Open Polar Server (OPS—An Open Source Infrastructure for the Cryosphere Community

Directory of Open Access Journals (Sweden)

Weibo Liu

2016-03-01

Full Text Available The Center for Remote Sensing of Ice Sheets (CReSIS at the University of Kansas has collected approximately 1000 terabytes (TB of radar depth sounding data over the Arctic and Antarctic ice sheets since 1993 in an effort to map the thickness of the ice sheets and ultimately understand the impacts of climate change and sea level rise. In addition to data collection, the storage, management, and public distribution of the dataset are also primary roles of the CReSIS. The Open Polar Server (OPS project developed a free and open source infrastructure to store, manage, analyze, and distribute the data collected by CReSIS in an effort to replace its current data storage and distribution approach. The OPS infrastructure includes a spatial database management system (DBMS, map and web server, JavaScript geoportal, and MATLAB application programming interface (API for the inclusion of data created by the cryosphere community. Open source software including GeoServer, PostgreSQL, PostGIS, OpenLayers, ExtJS, GeoEXT and others are used to build a system that modernizes the CReSIS data distribution for the entire cryosphere community and creates a flexible platform for future development. Usability analysis demonstrates the OPS infrastructure provides an improved end user experience. In addition, interpolating glacier topography is provided as an application example of the system.

A Capacity Supply Model for Virtualized Servers

Directory of Open Access Journals (Sweden)

Alexander PINNOW

2009-01-01

Full Text Available This paper deals with determining the capacity supply for virtualized servers. First, a server is modeled as a queue based on a Markov chain. Then, the effect of server virtualization on the capacity supply will be analyzed with the distribution function of the server load.

Automatic processing of multimodal tomography datasets.

Science.gov (United States)

Parsons, Aaron D; Price, Stephen W T; Wadeson, Nicola; Basham, Mark; Beale, Andrew M; Ashton, Alun W; Mosselmans, J Frederick W; Quinn, Paul D

2017-01-01

With the development of fourth-generation high-brightness synchrotrons on the horizon, the already large volume of data that will be collected on imaging and mapping beamlines is set to increase by orders of magnitude. As such, an easy and accessible way of dealing with such large datasets as quickly as possible is required in order to be able to address the core scientific problems during the experimental data collection. Savu is an accessible and flexible big data processing framework that is able to deal with both the variety and the volume of data of multimodal and multidimensional scientific datasets output such as those from chemical tomography experiments on the I18 microfocus scanning beamline at Diamond Light Source.

Windows Server 2012 R2 administrator cookbook

CERN Document Server

Krause, Jordan

2015-01-01

This book is intended for system administrators and IT professionals with experience in Windows Server 2008 or Windows Server 2012 environments who are looking to acquire the skills and knowledge necessary to manage and maintain the core infrastructure required for a Windows Server 2012 and Windows Server 2012 R2 environment.

Expitope: a web server for epitope expression.

Science.gov (United States)

Haase, Kerstin; Raffegerst, Silke; Schendel, Dolores J; Frishman, Dmitrij

2015-06-01

Adoptive T cell therapies based on introduction of new T cell receptors (TCRs) into patient recipient T cells is a promising new treatment for various kinds of cancers. A major challenge, however, is the choice of target antigens. If an engineered TCR can cross-react with self-antigens in healthy tissue, the side-effects can be devastating. We present the first web server for assessing epitope sharing when designing new potential lead targets. We enable the users to find all known proteins containing their peptide of interest. The web server returns not only exact matches, but also approximate ones, allowing a number of mismatches of the users choice. For the identified candidate proteins the expression values in various healthy tissues, representing all vital human organs, are extracted from RNA Sequencing (RNA-Seq) data as well as from some cancer tissues as control. All results are returned to the user sorted by a score, which is calculated using well-established methods and tools for immunological predictions. It depends on the probability that the epitope is created by proteasomal cleavage and its affinities to the transporter associated with antigen processing and the major histocompatibility complex class I alleles. With this framework, we hope to provide a helpful tool to exclude potential cross-reactivity in the early stage of TCR selection for use in design of adoptive T cell immunotherapy. The Expitope web server can be accessed via http://webclu.bio.wzw.tum.de/expitope. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

NRSAS: Nuclear Receptor Structure Analysis Servers.

NARCIS (Netherlands)

Bettler, E.J.M.; Krause, R.; Horn, F.; Vriend, G.

2003-01-01

We present a coherent series of servers that can perform a large number of structure analyses on nuclear hormone receptors. These servers are part of the NucleaRDB project, which provides a powerful information system for nuclear hormone receptors. The computations performed by the servers include

MCSA Windows Server 2012 R2 complete study guide exams 70-410, 70-411, 70-412, and 70-417

CERN Document Server

Panek, William

2014-01-01

Prepare for the MCSA Windows Server 2012 R2 Exams Microsoft's new version of the MCSA certification for WindowsServer 2012 R2 requires passing three exams (or one Upgrade exam ifyou have your MCSA or MCITP in Windows Server 2008). Thisvalue-priced study guide includes more than 1,000 pages of qualityexam-prep content, covering 100% of the objective domains of allthree exams (as well as the Upgrade exam, 70-417). In addition, you get access to an interactive practice testenvironment with more than 500 questions, electronic flashcards,and videos showing how to perform the more difficult tasks.

Microsoft® Exchange Server 2010 Inside Out

CERN Document Server

Redmond, Tony

2010-01-01

Dive into Exchange Server 2010 and SP1-and discover how to really put your messaging solutions to work! This well-organized and in-depth reference packs all the details you need to deploy and manage Exchange 2010, including hundreds of timesaving solutions, expert tips, and workarounds.Topics include preparing for the deployment of Exchange 2010; new features of Service Pack 1; using Remote PowerShell and the Exchange Management Shell; understanding how the new Role Based Access Control (RBAC) permissions model works and how to customize it to your requirements; the new high availability mode

Mergeomics: a web server for identifying pathological pathways, networks, and key regulators via multidimensional data integration.

Science.gov (United States)

Arneson, Douglas; Bhattacharya, Anindya; Shu, Le; Mäkinen, Ville-Petteri; Yang, Xia

2016-09-09

Human diseases are commonly the result of multidimensional changes at molecular, cellular, and systemic levels. Recent advances in genomic technologies have enabled an outpour of omics datasets that capture these changes. However, separate analyses of these various data only provide fragmented understanding and do not capture the holistic view of disease mechanisms. To meet the urgent needs for tools that effectively integrate multiple types of omics data to derive biological insights, we have developed Mergeomics, a computational pipeline that integrates multidimensional disease association data with functional genomics and molecular networks to retrieve biological pathways, gene networks, and central regulators critical for disease development. To make the Mergeomics pipeline available to a wider research community, we have implemented an online, user-friendly web server ( http://mergeomics. idre.ucla.edu/ ). The web server features a modular implementation of the Mergeomics pipeline with detailed tutorials. Additionally, it provides curated genomic resources including tissue-specific expression quantitative trait loci, ENCODE functional annotations, biological pathways, and molecular networks, and offers interactive visualization of analytical results. Multiple computational tools including Marker Dependency Filtering (MDF), Marker Set Enrichment Analysis (MSEA), Meta-MSEA, and Weighted Key Driver Analysis (wKDA) can be used separately or in flexible combinations. User-defined summary-level genomic association datasets (e.g., genetic, transcriptomic, epigenomic) related to a particular disease or phenotype can be uploaded and computed real-time to yield biologically interpretable results, which can be viewed online and downloaded for later use. Our Mergeomics web server offers researchers flexible and user-friendly tools to facilitate integration of multidimensional data into holistic views of disease mechanisms in the form of tissue-specific key regulators

Mastering Windows Server 2008 Networking Foundations

CERN Document Server

Minasi, Mark; Mueller, John Paul

2011-01-01

Find in-depth coverage of general networking concepts and basic instruction on Windows Server 2008 installation and management including active directory, DNS, Windows storage, and TCP/IP and IPv4 networking basics in Mastering Windows Server 2008 Networking Foundations. One of three new books by best-selling author Mark Minasi, this guide explains what servers do, how basic networking works (IP basics and DNS/WINS basics), and the fundamentals of the under-the-hood technologies that support staff must understand. Learn how to install Windows Server 2008 and build a simple network, security co

National Medical Terminology Server in Korea

Science.gov (United States)

Lee, Sungin; Song, Seung-Jae; Koh, Soonjeong; Lee, Soo Kyoung; Kim, Hong-Gee

Interoperable EHR (Electronic Health Record) necessitates at least the use of standardized medical terminologies. This paper describes a medical terminology server, LexCare Suite, which houses terminology management applications, such as a terminology editor, and a terminology repository populated with international standard terminology systems such as Systematized Nomenclature of Medicine (SNOMED). The server is to satisfy the needs of quality terminology systems to local primary to tertiary hospitals. Our partner general hospitals have used the server to test its applicability. This paper describes the server and the results of the applicability test.

Oceanotron, Scalable Server for Marine Observations

Science.gov (United States)

Loubrieu, T.; Bregent, S.; Blower, J. D.; Griffiths, G.

2013-12-01

Ifremer, French marine institute, is deeply involved in data management for different ocean in-situ observation programs (ARGO, OceanSites, GOSUD, ...) or other European programs aiming at networking ocean in-situ observation data repositories (myOcean, seaDataNet, Emodnet). To capitalize the effort for implementing advance data dissemination services (visualization, download with subsetting) for these programs and generally speaking water-column observations repositories, Ifremer decided to develop the oceanotron server (2010). Knowing the diversity of data repository formats (RDBMS, netCDF, ODV, ...) and the temperamental nature of the standard interoperability interface profiles (OGC/WMS, OGC/WFS, OGC/SOS, OpeNDAP, ...), the server is designed to manage plugins: - StorageUnits : which enable to read specific data repository formats (netCDF/OceanSites, RDBMS schema, ODV binary format). - FrontDesks : which get external requests and send results for interoperable protocols (OGC/WMS, OGC/SOS, OpenDAP). In between a third type of plugin may be inserted: - TransformationUnits : which enable ocean business related transformation of the features (for example conversion of vertical coordinates from pressure in dB to meters under sea surface). The server is released under open-source license so that partners can develop their own plugins. Within MyOcean project, University of Reading has plugged a WMS implementation as an oceanotron frontdesk. The modules are connected together by sharing the same information model for marine observations (or sampling features: vertical profiles, point series and trajectories), dataset metadata and queries. The shared information model is based on OGC/Observation & Measurement and Unidata/Common Data Model initiatives. The model is implemented in java (http://www.ifremer.fr/isi/oceanotron/javadoc/). This inner-interoperability level enables to capitalize ocean business expertise in software development without being indentured to

Dataset of Fourier transform-infrared coupled with chemometric analysis used to distinguish accessions of Garcinia mangostana L. in Peninsular Malaysia

Directory of Open Access Journals (Sweden)

Sri A’jilah Samsir

2016-09-01

Full Text Available In this dataset, we distinguish 15 accessions of Garcinia mangostana from Peninsular Malaysia using Fourier transform-infrared spectroscopy coupled with chemometric analysis. We found that the position and intensity of characteristic peaks at 3600–3100 cm−1 in IR spectra allowed discrimination of G. mangostana from different locations. Further principal component analysis (PCA of all the accessions suggests the two main clusters were formed: samples from Johor, Melaka, and Negeri Sembilan (South were clustered together in one group while samples from Perak, Kedah, Penang, Selangor, Kelantan, and Terengganu (North and East Coast were in another clustered group. Keywords: Apomictic, Mangosteen, Fourier Transformed-Infrared, Peninsular Malaysia

Environmental Dataset Gateway (EDG) REST Interface

Data.gov (United States)

U.S. Environmental Protection Agency — Use the Environmental Dataset Gateway (EDG) to find and access EPA's environmental resources. Many options are available for easily reusing EDG content in other...

UNRES server for physics-based coarse-grained simulations and prediction of protein structure, dynamics and thermodynamics.

Science.gov (United States)

Czaplewski, Cezary; Karczynska, Agnieszka; Sieradzan, Adam K; Liwo, Adam

2018-04-30

A server implementation of the UNRES package (http://www.unres.pl) for coarse-grained simulations of protein structures with the physics-based UNRES model, coined a name UNRES server, is presented. In contrast to most of the protein coarse-grained models, owing to its physics-based origin, the UNRES force field can be used in simulations, including those aimed at protein-structure prediction, without ancillary information from structural databases; however, the implementation includes the possibility of using restraints. Local energy minimization, canonical molecular dynamics simulations, replica exchange and multiplexed replica exchange molecular dynamics simulations can be run with the current UNRES server; the latter are suitable for protein-structure prediction. The user-supplied input includes protein sequence and, optionally, restraints from secondary-structure prediction or small x-ray scattering data, and simulation type and parameters which are selected or typed in. Oligomeric proteins, as well as those containing D-amino-acid residues and disulfide links can be treated. The output is displayed graphically (minimized structures, trajectories, final models, analysis of trajectory/ensembles); however, all output files can be downloaded by the user. The UNRES server can be freely accessed at http://unres-server.chem.ug.edu.pl.

Improving Data Discovery, Access, and Analysis to More Than Three Decades of Oceanographic and Geomorphologic Observations

Science.gov (United States)

Forte, M.; Hesser, T.; Knee, K.; Ingram, I.; Hathaway, K. K.; Brodie, K. L.; Spore, N.; Bird, A.; Fratantonio, R.; Dopsovic, R.; Keith, A.; Gadomski, K.

2016-02-01

The U.S. Army Engineer Research and Development Center's (USACE ERDC) Coastal and Hydraulics Laboratory (CHL) Coastal Observations and Analysis Branch (COAB) Measurements Program has a 35-year record of coastal observations. These datasets include oceanographic point source measurements, Real-Time Kinematic (RTK) GPS bathymetry surveys, and remote sensing data from both the Field Research Facility (FRF) in Duck, NC and from other project and experiment sites around the nation. The data has been used to support a variety of USACE mission areas, including coastal wave model development, beach and bar response, coastal project design, coastal storm surge, and other coastal hazard investigations. Furthermore these data have been widely used by a number of federal and state agencies, academic institutions, and private industries in hundreds of scientific and engineering investigations, publications, conference presentations and model advancement studies. A limiting factor to the use of FRF data has been rapid, reliable access and publicly available metadata for each data type. The addition of web tools, accessible data files, and well-documented metadata will open the door to much future collaboration. With the help of industry partner RPS ASA and the U.S. Army Corps of Engineers Mobile District Spatial Data Branch, a Data Integration Framework (DIF) was developed. The DIF represents a combination of processes, standards, people, and tools used to transform disconnected enterprise data into useful, easily accessible information for analysis and reporting. A front-end data portal connects the user to the framework that integrates both oceanographic observation and geomorphology measurements using a combination of ESRI and open-source technology while providing a seamless data discovery, access, and analysis experience to the user. The user interface was built with ESRI's JavaScript API and all project metadata is managed using Geoportal. The geomorphology data is made

A User Guide to the ION Work Group Server

CERN Document Server

Miotto, A; CERN. Geneva; Jones, R W L; Dodgson, M; Miotto, A

1999-01-01

This guide describes the computing ressources available to the member of the ALICE collaboration. It includes a description of: the general services such as PLUS, SHIFT and CSF; the services such as the ION and NA49 WGS (Work Group Servers) dedicated to the members of ALICE and of the other heavy ion experiments at CERN; some Unix tools such as AFS, shells, HEPiX X11 environment, LSF etc; the access to magnetic tapes. This document is also available in pdf format.

PELE web server: atomistic study of biomolecular systems at your fingertips.

Science.gov (United States)

Madadkar-Sobhani, Armin; Guallar, Victor

2013-07-01

PELE, Protein Energy Landscape Exploration, our novel technology based on protein structure prediction algorithms and a Monte Carlo sampling, is capable of modelling the all-atom protein-ligand dynamical interactions in an efficient and fast manner, with two orders of magnitude reduced computational cost when compared with traditional molecular dynamics techniques. PELE's heuristic approach generates trial moves based on protein and ligand perturbations followed by side chain sampling and global/local minimization. The collection of accepted steps forms a stochastic trajectory. Furthermore, several processors may be run in parallel towards a collective goal or defining several independent trajectories; the whole procedure has been parallelized using the Message Passing Interface. Here, we introduce the PELE web server, designed to make the whole process of running simulations easier and more practical by minimizing input file demand, providing user-friendly interface and producing abstract outputs (e.g. interactive graphs and tables). The web server has been implemented in C++ using Wt (http://www.webtoolkit.eu) and MySQL (http://www.mysql.com). The PELE web server, accessible at http://pele.bsc.es, is free and open to all users with no login requirement.

CheD: chemical database compilation tool, Internet server, and client for SQL servers.

Science.gov (United States)

Trepalin, S V; Yarkov, A V

2001-01-01

An efficient program, which runs on a personal computer, for the storage, retrieval, and processing of chemical information, is presented, The program can work both as a stand-alone application or in conjunction with a specifically written Web server application or with some standard SQL servers, e.g., Oracle, Interbase, and MS SQL. New types of data fields are introduced, e.g., arrays for spectral information storage, HTML and database links, and user-defined functions. CheD has an open architecture; thus, custom data types, controls, and services may be added. A WWW server application for chemical data retrieval features an easy and user-friendly installation on Windows NT or 95 platforms.

ORION: a web server for protein fold recognition and structure prediction using evolutionary hybrid profiles.

Science.gov (United States)

Ghouzam, Yassine; Postic, Guillaume; Guerin, Pierre-Edouard; de Brevern, Alexandre G; Gelly, Jean-Christophe

2016-06-20

Protein structure prediction based on comparative modeling is the most efficient way to produce structural models when it can be performed. ORION is a dedicated webserver based on a new strategy that performs this task. The identification by ORION of suitable templates is performed using an original profile-profile approach that combines sequence and structure evolution information. Structure evolution information is encoded into profiles using structural features, such as solvent accessibility and local conformation -with Protein Blocks-, which give an accurate description of the local protein structure. ORION has recently been improved, increasing by 5% the quality of its results. The ORION web server accepts a single protein sequence as input and searches homologous protein structures within minutes. Various databases such as PDB, SCOP and HOMSTRAD can be mined to find an appropriate structural template. For the modeling step, a protein 3D structure can be directly obtained from the selected template by MODELLER and displayed with global and local quality model estimation measures. The sequence and the predicted structure of 4 examples from the CAMEO server and a recent CASP11 target from the 'Hard' category (T0818-D1) are shown as pertinent examples. Our web server is accessible at http://www.dsimb.inserm.fr/ORION/.

The TOPCONS web server for consensus prediction of membrane protein topology and signal peptides.

Science.gov (United States)

Tsirigos, Konstantinos D; Peters, Christoph; Shu, Nanjiang; Käll, Lukas; Elofsson, Arne

2015-07-01

TOPCONS (http://topcons.net/) is a widely used web server for consensus prediction of membrane protein topology. We hereby present a major update to the server, with some substantial improvements, including the following: (i) TOPCONS can now efficiently separate signal peptides from transmembrane regions. (ii) The server can now differentiate more successfully between globular and membrane proteins. (iii) The server now is even slightly faster, although a much larger database is used to generate the multiple sequence alignments. For most proteins, the final prediction is produced in a matter of seconds. (iv) The user-friendly interface is retained, with the additional feature of submitting batch files and accessing the server programmatically using standard interfaces, making it thus ideal for proteome-wide analyses. Indicatively, the user can now scan the entire human proteome in a few days. (v) For proteins with homology to a known 3D structure, the homology-inferred topology is also displayed. (vi) Finally, the combination of methods currently implemented achieves an overall increase in performance by 4% as compared to the currently available best-scoring methods and TOPCONS is the only method that can identify signal peptides and still maintain a state-of-the-art performance in topology predictions. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

LigSearch: a knowledge-based web server to identify likely ligands for a protein target

Energy Technology Data Exchange (ETDEWEB)

Beer, Tjaart A. P. de; Laskowski, Roman A. [European Bioinformatics Institute (EMBL–EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD (United Kingdom); Duban, Mark-Eugene [Northwestern University Feinberg School of Medicine, Chicago, Illinois (United States); Chan, A. W. Edith [University College London, London WC1E 6BT (United Kingdom); Anderson, Wayne F. [Northwestern University Feinberg School of Medicine, Chicago, Illinois (United States); Thornton, Janet M., E-mail: thornton@ebi.ac.uk [European Bioinformatics Institute (EMBL–EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD (United Kingdom)

2013-12-01

LigSearch is a web server for identifying ligands likely to bind to a given protein. Identifying which ligands might bind to a protein before crystallization trials could provide a significant saving in time and resources. LigSearch, a web server aimed at predicting ligands that might bind to and stabilize a given protein, has been developed. Using a protein sequence and/or structure, the system searches against a variety of databases, combining available knowledge, and provides a clustered and ranked output of possible ligands. LigSearch can be accessed at http://www.ebi.ac.uk/thornton-srv/databases/LigSearch.

Public Access Points, Location of public beach access along the Oregon Coast. Boat ramp locations were added to the dataset to allow users to view the location of boat ramps along the Columbia River and the Willamete River north of the Oregon City Dam., Published in 2005, 1:100000 (1in=8333ft) scale, Oregon Geospatial Enterprise Office (GEO).

Data.gov (United States)

NSGIC State | GIS Inventory — Public Access Points dataset current as of 2005. Location of public beach access along the Oregon Coast. Boat ramp locations were added to the dataset to allow users...

Mastering Microsoft Windows Server 2008 R2

CERN Document Server

Minasi, Mark; Finn, Aidan

2010-01-01

The one book you absolutely need to get up and running with Windows Server 2008 R2. One of the world's leading Windows authorities and top-selling author Mark Minasi explores every nook and cranny of the latest version of Microsoft's flagship network operating system, Windows Server 2008 R2, giving you the most in-depth coverage in any book on the market.: Focuses on Windows Windows Server 2008 R2, the newest version of Microsoft's Windows' server line of operating system, and the ideal server for new Windows 7 clients; Author Mark Minasi is one of the world's leading Windows authorities and h

Mastering Windows Server 2012 R2

CERN Document Server

Minasi, Mark; Booth, Christian; Butler, Robert; McCabe, John; Panek, Robert; Rice, Michael; Roth, Stefan

2013-01-01

Check out the new Hyper-V, find new and easier ways to remotely connect back into the office, or learn all about Storage Spaces-these are just a few of the features in Windows Server 2012 R2 that are explained in this updated edition from Windows authority Mark Minasi and a team of Windows Server experts led by Kevin Greene. This book gets you up to speed on all of the new features and functions of Windows Server, and includes real-world scenarios to put them in perspective. If you're a system administrator upgrading to, migrating to, or managing Windows Server 2012 R2, find what you need to

Support the Open Access Movement

CERN Multimedia

2005-01-01

CERN's Executive Board recently endorsed a new policy of open access to the laboratory's results: Continuing CERN action on Open Access (OA) [http://cds.cern.ch/record/828991/files/open-2005-006.pdf]. What does this policy mean for you? CERN authors have two responsibilities: Submit your document to the CERN Document Server; Consider submitting future articles to an Open Access journal. Since 2001, Operational Circular No. 6 has required every CERN author (Staff member, Fellow, or any Associated member of personnel who is allowed to use CERN as his affiliation) to submit a copy of their scientific documents to the CERN Document Server (CDS). For some groups all approved documents are submitted by the secretary (see the Departments' policies at: http://library.cern.ch/cern_publications/cern_publication_policy.html). Each author should personally also ensure the submission of any other articles which are not added in this way, such as conference contributions and review articles. It is not sufficient to re...

An adversarial queueing model for online server routing

NARCIS (Netherlands)

Bonifaci, V.

2007-01-01

In an online server routing problem, a vehicle or server moves in a network in order to process incoming requests at the nodes. Online server routing problems have been thoroughly studied using competitive analysis. We propose a new model for online server routing, based on adversarial queueing

TrackingNet: A Large-Scale Dataset and Benchmark for Object Tracking in the Wild

KAUST Repository

Mü ller, Matthias; Bibi, Adel Aamer; Giancola, Silvio; Al-Subaihi, Salman; Ghanem, Bernard

2018-01-01

Despite the numerous developments in object tracking, further development of current tracking algorithms is limited by small and mostly saturated datasets. As a matter of fact, data-hungry trackers based on deep-learning currently rely on object detection datasets due to the scarcity of dedicated large-scale tracking datasets. In this work, we present TrackingNet, the first large-scale dataset and benchmark for object tracking in the wild. We provide more than 30K videos with more than 14 million dense bounding box annotations. Our dataset covers a wide selection of object classes in broad and diverse context. By releasing such a large-scale dataset, we expect deep trackers to further improve and generalize. In addition, we introduce a new benchmark composed of 500 novel videos, modeled with a distribution similar to our training dataset. By sequestering the annotation of the test set and providing an online evaluation server, we provide a fair benchmark for future development of object trackers. Deep trackers fine-tuned on a fraction of our dataset improve their performance by up to 1.6% on OTB100 and up to 1.7% on TrackingNet Test. We provide an extensive benchmark on TrackingNet by evaluating more than 20 trackers. Our results suggest that object tracking in the wild is far from being solved.

TrackingNet: A Large-Scale Dataset and Benchmark for Object Tracking in the Wild

KAUST Repository

Müller, Matthias

2018-03-28

Despite the numerous developments in object tracking, further development of current tracking algorithms is limited by small and mostly saturated datasets. As a matter of fact, data-hungry trackers based on deep-learning currently rely on object detection datasets due to the scarcity of dedicated large-scale tracking datasets. In this work, we present TrackingNet, the first large-scale dataset and benchmark for object tracking in the wild. We provide more than 30K videos with more than 14 million dense bounding box annotations. Our dataset covers a wide selection of object classes in broad and diverse context. By releasing such a large-scale dataset, we expect deep trackers to further improve and generalize. In addition, we introduce a new benchmark composed of 500 novel videos, modeled with a distribution similar to our training dataset. By sequestering the annotation of the test set and providing an online evaluation server, we provide a fair benchmark for future development of object trackers. Deep trackers fine-tuned on a fraction of our dataset improve their performance by up to 1.6% on OTB100 and up to 1.7% on TrackingNet Test. We provide an extensive benchmark on TrackingNet by evaluating more than 20 trackers. Our results suggest that object tracking in the wild is far from being solved.

Something From Nothing (There): Collecting Global IPv6 Datasets from DNS

NARCIS (Netherlands)

Fiebig, T.; Borgolte, Kevin; Hao, Shuang; Kruegel, Christopher; Vigna, Giovanny; Spring, Neil; Riley, George F.

2017-01-01

Current large-scale IPv6 studies mostly rely on non-public datasets, asmost public datasets are domain specific. For instance, traceroute-based datasetsare biased toward network equipment. In this paper, we present a new methodologyto collect IPv6 address datasets that does not require access to

Creation of a Web-Based GIS Server and Custom Geoprocessing Tools for Enhanced Hydrologic Applications

Science.gov (United States)

Welton, B.; Chouinard, K.; Sultan, M.; Becker, D.; Milewski, A.; Becker, R.

2010-12-01

Rising populations in the arid and semi arid parts of the World are increasing the demand for fresh water supplies worldwide. Many data sets needed for assessment of hydrologic applications across vast regions of the world are expensive, unpublished, difficult to obtain, or at varying scales which complicates their use. Fortunately, this situation is changing with the development of global remote sensing datasets and web-based platforms such as GIS Server. GIS provides a cost effective vehicle for comparing, analyzing, and querying a variety of spatial datasets as geographically referenced layers. We have recently constructed a web-based GIS, that incorporates all relevant geological, geochemical, geophysical, and remote sensing data sets that were readily used to identify reservoir types and potential well locations on local and regional scales in various tectonic settings including: (1) extensional environment (Red Sea rift), (2) transcurrent fault system (Najd Fault in the Arabian-Nubian Shield), and (3) compressional environments (Himalayas). The web-based GIS could also be used to detect spatial and temporal trends in precipitation, recharge, and runoff in large watersheds on local, regional, and continental scales. These applications were enabled through the construction of a web-based ArcGIS Server with Google Map’s interface and the development of customized geoprocessing tools. ArcGIS Server provides out-of-the-box setups that are generic in nature. This platform includes all of the standard web based GIS tools (e.g. pan, zoom, identify, search, data querying, and measurement). In addition to the standard suite of tools provided by ArcGIS Server an additional set of advanced data manipulation and display tools was also developed to allow for a more complete and customizable view of the area of interest. The most notable addition to the standard GIS Server tools is the custom on-demand geoprocessing tools (e.g., graph, statistical functions, custom raster

Open data used in water sciences - Review of access, licenses and understandability

Science.gov (United States)

Falkenroth, Esa; Lagerbäck Adolphi, Emma; Arheimer, Berit

2016-04-01

The amount of open data available for hydrology research is continually growing. In the EU-funded project SWITCH-ON (Sharing Water-related Information to Tackle Changes in the Hydrosphere - for Operational Needs: www.water-switch-on.eu), we are addressing water concerns by exploring and exploiting the untapped potential of these new open data. This work is enabled by many ongoing efforts to facilitate the use of open data. For instance, a number of portals provide the means to search for open data sets and open spatial data services (such as the GEOSS Portal, INSPIRE community geoportal or various Climate Services and public portals). However, in general, many research groups in water sciences still hesitate in using this open data. We therefore examined some limiting factors. Factors that limit usability of a dataset include: (1) accessibility, (2) understandability and (3) licences. In the SWITCH-ON project we have developed a search tool for finding and accessing data with relevance to water science in Europe, as the existing ones are not addressing data needs in water sciences specifically. The tool is filled with some 9000 sets of metadata and each one is linked to water related key-words. The keywords are based on the ones developed within the CUAHSI community in USA, but extended with non-hydrosphere topics, additional subclasses and only showing keywords actually having data. Access to data sets: 78% of the data is directly accessible, while the rest is either available after registration and request, or through a web client for visualisation but without direct download. However, several data sets were found to be inaccessible due to server downtime, incorrect links or problems with the host database management system. One possible explanation for this could be that many datasets have been assembled by research project that no longer are funded. Hence, their server infrastructure would be less maintained compared to large-scale operational services

A tandem queue with delayed server release

OpenAIRE

Nawijn, W.M.

1997-01-01

We consider a tandem queue with two stations. The rst station is an s-server queue with Poisson arrivals and exponential service times. After terminating his service in the rst station, a customer enters the second station to require service at an exponential single server, while in the meantime he is blocking his server in station 1 until he completes service in station 2, whereupon the server in station 1 is released. An analysis of the generating function of the simultaneous probability di...

Parallel Computing Using Web Servers and "Servlets".

Science.gov (United States)

Lo, Alfred; Bloor, Chris; Choi, Y. K.

2000-01-01

Describes parallel computing and presents inexpensive ways to implement a virtual parallel computer with multiple Web servers. Highlights include performance measurement of parallel systems; models for using Java and intranet technology including single server, multiple clients and multiple servers, single client; and a comparison of CGI (common…

JAFA: a protein function annotation meta-server

DEFF Research Database (Denmark)

Friedberg, Iddo; Harder, Tim; Godzik, Adam

2006-01-01

Annotations, or JAFA server. JAFA queries several function prediction servers with a protein sequence and assembles the returned predictions in a legible, non-redundant format. In this manner, JAFA combines the predictions of several servers to provide a comprehensive view of what are the predicted functions...

A polling model with an autonomous server

NARCIS (Netherlands)

de Haan, Roland; Boucherie, Richardus J.; van Ommeren, Jan C.W.

Polling models are used as an analytical performance tool in several application areas. In these models, the focus often is on controlling the operation of the server as to optimize some performance measure. For several applications, controlling the server is not an issue as the server moves

Passive Detection of Misbehaving Name Servers

Science.gov (United States)

2013-10-01

name servers that changed IP address five or more times in a month. Solid red line indicates those servers possibly linked to pharmaceutical scams . 12...malicious and stated that fast-flux hosting “is considered one of the most serious threats to online activities today” [ICANN 2008, p. 2]. The...that time, apparently independent of filters on name-server flux, a large number of pharmaceutical scams1 were taken down. These scams apparently

Creation of the Naturalistic Engagement in Secondary Tasks (NEST) distracted driving dataset.

Science.gov (United States)

Owens, Justin M; Angell, Linda; Hankey, Jonathan M; Foley, James; Ebe, Kazutoshi

2015-09-01

Distracted driving has become a topic of critical importance to driving safety research over the past several decades. Naturalistic driving data offer a unique opportunity to study how drivers engage with secondary tasks in real-world driving; however, the complexities involved with identifying and coding relevant epochs of naturalistic data have limited its accessibility to the general research community. This project was developed to help address this problem by creating an accessible dataset of driver behavior and situational factors observed during distraction-related safety-critical events and baseline driving epochs, using the Strategic Highway Research Program 2 (SHRP2) naturalistic dataset. The new NEST (Naturalistic Engagement in Secondary Tasks) dataset was created using crashes and near-crashes from the SHRP2 dataset that were identified as including secondary task engagement as a potential contributing factor. Data coding included frame-by-frame video analysis of secondary task and hands-on-wheel activity, as well as summary event information. In addition, information about each secondary task engagement within the trip prior to the crash/near-crash was coded at a higher level. Data were also coded for four baseline epochs and trips per safety-critical event. 1,180 events and baseline epochs were coded, and a dataset was constructed. The project team is currently working to determine the most useful way to allow broad public access to the dataset. We anticipate that the NEST dataset will be extraordinarily useful in allowing qualified researchers access to timely, real-world data concerning how drivers interact with secondary tasks during safety-critical events and baseline driving. The coded dataset developed for this project will allow future researchers to have access to detailed data on driver secondary task engagement in the real world. It will be useful for standalone research, as well as for integration with additional SHRP2 data to enable the

The ARAC client system: network-based access to ARAC

International Nuclear Information System (INIS)

Leach, M J; Sumikawa, D; Webster, C

1999-01-01

The ARAC Client System allows users (such as emergency managers and first responders) with commonly available desktop and laptop computers to utilize the central ARAC system over the Internet or any other communications link using Internet protocols. Providing cost-effective fast access to the central ARAC system greatly expands the availability of the ARAC capability. The ARAC Client system consists of (1) local client applications running on the remote user's computer, and (2) ''site servers'' that provide secure access to selected central ARAC system capabilities and run on a scalable number of dedicated workstations residing at the central facility. The remote client applications allow users to describe a real or potential them-bio event, electronically sends this information to the central ARAC system which performs model calculations, and quickly receive and visualize the resulting graphical products. The site servers will support simultaneous access to ARAC capabilities by multiple users. The ARAC Client system is based on object-oriented client/server and distributed computing technologies using CORBA and Java, and consists of a large number of interacting components

COMAN: a web server for comprehensive metatranscriptomics analysis.

Science.gov (United States)

Ni, Yueqiong; Li, Jun; Panagiotou, Gianni

2016-08-11

Microbiota-oriented studies based on metagenomic or metatranscriptomic sequencing have revolutionised our understanding on microbial ecology and the roles of both clinical and environmental microbes. The analysis of massive metatranscriptomic data requires extensive computational resources, a collection of bioinformatics tools and expertise in programming. We developed COMAN (Comprehensive Metatranscriptomics Analysis), a web-based tool dedicated to automatically and comprehensively analysing metatranscriptomic data. COMAN pipeline includes quality control of raw reads, removal of reads derived from non-coding RNA, followed by functional annotation, comparative statistical analysis, pathway enrichment analysis, co-expression network analysis and high-quality visualisation. The essential data generated by COMAN are also provided in tabular format for additional analysis and integration with other software. The web server has an easy-to-use interface and detailed instructions, and is freely available at http://sbb.hku.hk/COMAN/ CONCLUSIONS: COMAN is an integrated web server dedicated to comprehensive functional analysis of metatranscriptomic data, translating massive amount of reads to data tables and high-standard figures. It is expected to facilitate the researchers with less expertise in bioinformatics in answering microbiota-related biological questions and to increase the accessibility and interpretation of microbiota RNA-Seq data.

An Improvement of Robust Biometrics-Based Authentication and Key Agreement Scheme for Multi-Server Environments Using Smart Cards.

Science.gov (United States)

Moon, Jongho; Choi, Younsung; Jung, Jaewook; Won, Dongho

2015-01-01

In multi-server environments, user authentication is a very important issue because it provides the authorization that enables users to access their data and services; furthermore, remote user authentication schemes for multi-server environments have solved the problem that has arisen from user's management of different identities and passwords. For this reason, numerous user authentication schemes that are designed for multi-server environments have been proposed over recent years. In 2015, Lu et al. improved upon Mishra et al.'s scheme, claiming that their remote user authentication scheme is more secure and practical; however, we found that Lu et al.'s scheme is still insecure and incorrect. In this paper, we demonstrate that Lu et al.'s scheme is vulnerable to outsider attack and user impersonation attack, and we propose a new biometrics-based scheme for authentication and key agreement that can be used in multi-server environments; then, we show that our proposed scheme is more secure and supports the required security properties.

Mastering Microsoft Windows Small Business Server 2008

CERN Document Server

Johnson, Steven

2010-01-01

A complete, winning approach to the number one small business solution. Do you have 75 or fewer users or devices on your small-business network? Find out how to integrate everything you need for your mini-enterprise with Microsoft's new Windows Server 2008 Small Business Server, a custom collection of server and management technologies designed to help small operations run smoothly without a giant IT department. This comprehensive guide shows you how to master all SBS components as well as handle integration with other Microsoft technologies.: Focuses on Windows Server 2008 Small Business Serv

Microsoft Windows Server 2012 administration instant reference

CERN Document Server

Hester, Matthew

2013-01-01

Fast, accurate answers for common Windows Server questions Serving as a perfect companion to all Windows Server books, this reference provides you with quick and easily searchable solutions to day-to-day challenges of Microsoft's newest version of Windows Server. Using helpful design features such as thumb tabs, tables of contents, and special heading treatments, this resource boasts a smooth and seamless approach to finding information. Plus, quick-reference tables and lists provide additional on-the-spot answers. Covers such key topics as server roles and functionality, u

An efficient biometric and password-based remote user authentication using smart card for Telecare Medical Information Systems in multi-server environment.

Science.gov (United States)

Maitra, Tanmoy; Giri, Debasis

2014-12-01

The medical organizations have introduced Telecare Medical Information System (TMIS) to provide a reliable facility by which a patient who is unable to go to a doctor in critical or urgent period, can communicate to a doctor through a medical server via internet from home. An authentication mechanism is needed in TMIS to hide the secret information of both parties, namely a server and a patient. Recent research includes patient's biometric information as well as password to design a remote user authentication scheme that enhances the security level. In a single server environment, one server is responsible for providing services to all the authorized remote patients. However, the problem arises if a patient wishes to access several branch servers, he/she needs to register to the branch servers individually. In 2014, Chuang and Chen proposed an remote user authentication scheme for multi-server environment. In this paper, we have shown that in their scheme, an non-register adversary can successfully logged-in into the system as a valid patient. To resist the weaknesses, we have proposed an authentication scheme for TMIS in multi-server environment where the patients can register to a root telecare server called registration center (RC) in one time to get services from all the telecare branch servers through their registered smart card. Security analysis and comparison shows that our proposed scheme provides better security with low computational and communication cost.

Web server for priority ordered multimedia services

Science.gov (United States)

Celenk, Mehmet; Godavari, Rakesh K.; Vetnes, Vermund

2001-10-01

In this work, our aim is to provide finer priority levels in the design of a general-purpose Web multimedia server with provisions of the CM services. The type of services provided include reading/writing a web page, downloading/uploading an audio/video stream, navigating the Web through browsing, and interactive video teleconferencing. The selected priority encoding levels for such operations follow the order of admin read/write, hot page CM and Web multicasting, CM read, Web read, CM write and Web write. Hot pages are the most requested CM streams (e.g., the newest movies, video clips, and HDTV channels) and Web pages (e.g., portal pages of the commercial Internet search engines). Maintaining a list of these hot Web pages and CM streams in a content addressable buffer enables a server to multicast hot streams with lower latency and higher system throughput. Cold Web pages and CM streams are treated as regular Web and CM requests. Interactive CM operations such as pause (P), resume (R), fast-forward (FF), and rewind (RW) have to be executed without allocation of extra resources. The proposed multimedia server model is a part of the distributed network with load balancing schedulers. The SM is connected to an integrated disk scheduler (IDS), which supervises an allocated disk manager. The IDS follows the same priority handling as the SM, and implements a SCAN disk-scheduling method for an improved disk access and a higher throughput. Different disks are used for the Web and CM services in order to meet the QoS requirements of CM services. The IDS ouput is forwarded to an Integrated Transmission Scheduler (ITS). The ITS creates a priority ordered buffering of the retrieved Web pages and CM data streams that are fed into an auto regressive moving average (ARMA) based traffic shaping circuitry before being transmitted through the network.

Server-side Statistics Scripting in PHP

Directory of Open Access Journals (Sweden)

Jan de Leeuw

1997-06-01

Full Text Available On the UCLA Statistics WWW server there are a large number of demos and calculators that can be used in statistics teaching and research. Some of these demos require substantial amounts of computation, others mainly use graphics. These calculators and demos are implemented in various different ways, reflecting developments in WWW based computing. As usual, one of the main choices is between doing the work on the client-side (i.e. in the browser or on the server-side (i.e. on our WWW server. Obviously, client-side computation puts fewer demands on the server. On the other hand, it requires that the client downloads Java applets, or installs plugins and/or helpers. If JavaScript is used, client-side computations will generally be slow. We also have to assume that the client is installed properly, and has the required capabilities. Requiring too much on the client-side has caused browsing machines such as Netscape Communicator to grow beyond all reasonable bounds, both in size and RAM requirements. Moreover requiring Java and JavaScript rules out such excellent browsers as Lynx or Emacs W3. For server-side computing, we can configure the server and its resources ourselves, and we need not worry about browser capabilities and configuration. Nothing needs to be downloaded, except the usual HTML pages and graphics. In the same way as on the client side, there is a scripting solution, where code is interpreted, or a ob ject-code solution using compiled code. For the server-side scripting, we use embedded languages, such as PHP/FI. The scripts in the HTML pages are interpreted by a CGI program, and the output of the CGI program is send to the clients. Of course the CGI program is compiled, but the statistics procedures will usually be interpreted, because PHP/FI does not have the appropriate functions in its scripting language. This will tend to be slow, because embedded languages do not deal efficiently with loops and similar constructs. Thus a first

Environmental Dataset Gateway (EDG) CS-W Interface

Data.gov (United States)

U.S. Environmental Protection Agency — Use the Environmental Dataset Gateway (EDG) to find and access EPA's environmental resources. Many options are available for easily reusing EDG content in other...

DIANA-microT web server: elucidating microRNA functions through target prediction.

Science.gov (United States)

Maragkakis, M; Reczko, M; Simossis, V A; Alexiou, P; Papadopoulos, G L; Dalamagas, T; Giannopoulos, G; Goumas, G; Koukis, E; Kourtis, K; Vergoulis, T; Koziris, N; Sellis, T; Tsanakas, P; Hatzigeorgiou, A G

2009-07-01

Computational microRNA (miRNA) target prediction is one of the key means for deciphering the role of miRNAs in development and disease. Here, we present the DIANA-microT web server as the user interface to the DIANA-microT 3.0 miRNA target prediction algorithm. The web server provides extensive information for predicted miRNA:target gene interactions with a user-friendly interface, providing extensive connectivity to online biological resources. Target gene and miRNA functions may be elucidated through automated bibliographic searches and functional information is accessible through Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. The web server offers links to nomenclature, sequence and protein databases, and users are facilitated by being able to search for targeted genes using different nomenclatures or functional features, such as the genes possible involvement in biological pathways. The target prediction algorithm supports parameters calculated individually for each miRNA:target gene interaction and provides a signal-to-noise ratio and a precision score that helps in the evaluation of the significance of the predicted results. Using a set of miRNA targets recently identified through the pSILAC method, the performance of several computational target prediction programs was assessed. DIANA-microT 3.0 achieved there with 66% the highest ratio of correctly predicted targets over all predicted targets. The DIANA-microT web server is freely available at www.microrna.gr/microT.

Effect of video server topology on contingency capacity requirements

Science.gov (United States)

Kienzle, Martin G.; Dan, Asit; Sitaram, Dinkar; Tetzlaff, William H.

1996-03-01

Video servers need to assign a fixed set of resources to each video stream in order to guarantee on-time delivery of the video data. If a server has insufficient resources to guarantee the delivery, it must reject the stream request rather than slowing down all existing streams. Large scale video servers are being built as clusters of smaller components, so as to be economical, scalable, and highly available. This paper uses a blocking model developed for telephone systems to evaluate video server cluster topologies. The goal is to achieve high utilization of the components and low per-stream cost combined with low blocking probability and high user satisfaction. The analysis shows substantial economies of scale achieved by larger server images. Simple distributed server architectures can result in partitioning of resources with low achievable resource utilization. By comparing achievable resource utilization of partitioned and monolithic servers, we quantify the cost of partitioning. Next, we present an architecture for a distributed server system that avoids resource partitioning and results in highly efficient server clusters. Finally, we show how, in these server clusters, further optimizations can be achieved through caching and batching of video streams.

RANCANG BANGUN PERANGKAT LUNAK MANAJEMEN DATABASE SQL SERVER BERBASIS WEB

Directory of Open Access Journals (Sweden)

Muchammad Husni

2005-01-01

Full Text Available Normal 0 false false false IN X-NONE X-NONE MicrosoftInternetExplorer4 Microsoft SQL Server merupakan aplikasi desktop database server yang bersifat client/server, karena memiliki komponen client, yang  berfungsi menampilkan dan memanipulasi data; serta komponen server yang berfungsi menyimpan, memanggil, dan mengamankan database. Operasi-operasi manajemen semua server database dalam jaringan dilakukan administrator database dengan menggunakan tool administratif utama SQL Server yang bernama Enterprise Manager. Hal ini mengakibatkan administrator database hanya bisa  melakukan operasi-operasi tersebut di komputer yang telah diinstalasi Microsoft SQL Server. Pada penelitian ini, dirancang suatu aplikasi berbasis web dengan menggunakan ASP.Net untuk melakukan pengaturan database server. Aplikasi ini menggunakan ADO.NET yang memanfaatkan Transact-SQL dan stored procedure pada server untuk melakukan operasi-operasi manajemen database pada suatu server database SQL, dan menampilkannya ke dalam web. Administrator database bisa menjalankan aplikasi berbasis web tersebut dari komputer mana saja pada jaringan dan melakukan koneksi ke server database SQL dengan menggunakan web browser. Dengan demikian memudahkan administrator melakukan tugasnya tanpa harus menggunakan komputer server.   Kata Kunci : Transact-SQL, ASP.Net, ADO.NET, SQL Server

Lowering the Barrier to Cross-Disciplinary Scientific Data Access via a Brokering Service Built Around a Unified Data Model

Science.gov (United States)

Lindholm, D. M.; Wilson, A.

2012-12-01

The steps many scientific data users go through to use data (after discovering it) can be rather tedious, even when dealing with datasets within their own discipline. Accessing data across domains often seems intractable. We present here, LaTiS, an Open Source brokering solution that bridges the gap between the source data and the user's code by defining a unified data model plus a plugin framework for "adapters" to read data from their native source, "filters" to perform server side data processing, and "writers" to output any number of desired formats or streaming protocols. A great deal of work is being done in the informatics community to promote multi-disciplinary science with a focus on search and discovery based on metadata - information about the data. The goal of LaTiS is to go that last step to provide a uniform interface to read the dataset into computer programs and other applications once it has been identified. The LaTiS solution for integrating a wide variety of data models is to return to mathematical fundamentals. The LaTiS data model emphasizes functional relationships between variables. For example, a time series of temperature measurements can be thought of as a function that maps a time to a temperature. With just three constructs: "Scalar" for a single variable, "Tuple" for a collection of variables, and "Function" to represent a set of independent and dependent variables, the LaTiS data model can represent most scientific datasets at a low level that enables uniform data access. Higher level abstractions can be built on top of the basic model to add more meaningful semantics for specific user communities. LaTiS defines its data model in terms of the Unified Modeling Language (UML). It also defines a very thin Java Interface that can be implemented by numerous existing data interfaces (e.g. NetCDF-Java) such that client code can access any dataset via the Java API, independent of the underlying data access mechanism. LaTiS also provides a

Super: a web server to rapidly screen superposable oligopeptide fragments from the protein data bank

Science.gov (United States)

Collier, James H.; Lesk, Arthur M.; Garcia de la Banda, Maria; Konagurthu, Arun S.

2012-01-01

Searching for well-fitting 3D oligopeptide fragments within a large collection of protein structures is an important task central to many analyses involving protein structures. This article reports a new web server, Super, dedicated to the task of rapidly screening the protein data bank (PDB) to identify all fragments that superpose with a query under a prespecified threshold of root-mean-square deviation (RMSD). Super relies on efficiently computing a mathematical bound on the commonly used structural similarity measure, RMSD of superposition. This allows the server to filter out a large proportion of fragments that are unrelated to the query; >99% of the total number of fragments in some cases. For a typical query, Super scans the current PDB containing over 80 500 structures (with ∼40 million potential oligopeptide fragments to match) in under a minute. Super web server is freely accessible from: http://lcb.infotech.monash.edu.au/super. PMID:22638586

Mastering Citrix XenServer

CERN Document Server

Reed, Martez

2014-01-01

If you are an administrator who is looking to gain a greater understanding of how to design and implement a virtualization solution based on Citrix® XenServer®, then this book is for you. The book will serve as an excellent resource for those who are already familiar with other virtualization platforms, such as Microsoft Hyper-V or VMware vSphere.The book assumes that you have a good working knowledge of servers, networking, and storage technologies.

Securing SQL Server Protecting Your Database from Attackers

CERN Document Server

Cherry, Denny

2012-01-01

Written by Denny Cherry, a Microsoft MVP for the SQL Server product, a Microsoft Certified Master for SQL Server 2008, and one of the biggest names in SQL Server today, Securing SQL Server, Second Edition explores the potential attack vectors someone can use to break into your SQL Server database as well as how to protect your database from these attacks. In this book, you will learn how to properly secure your database from both internal and external threats using best practices and specific tricks the author uses in his role as an independent consultant while working on some of the largest

Securing SQL server protecting your database from attackers

CERN Document Server

Cherry, Denny

2015-01-01

SQL server is the most widely-used database platform in the world, and a large percentage of these databases are not properly secured, exposing sensitive customer and business data to attack. In Securing SQL Server, Third Edition, you will learn about the potential attack vectors that can be used to break into SQL server databases as well as how to protect databases from these attacks. In this book, Denny Cherry - a Microsoft SQL MVP and one of the biggest names in SQL server - will teach you how to properly secure an SQL server database from internal and external threats using best practic

Server farms with setup costs

NARCIS (Netherlands)

Gandhi, A.; Harchol-Balter, M.; Adan, I.J.B.F.

2010-01-01

In this paper we consider server farms with a setup cost. This model is common in manufacturing systems and data centers, where there is a cost to turn servers on. Setup costs always take the form of a time delay, and sometimes there is additionally a power penalty, as in the case of data centers.

TBI server: a web server for predicting ion effects in RNA folding.

Science.gov (United States)

Zhu, Yuhong; He, Zhaojian; Chen, Shi-Jie

2015-01-01

Metal ions play a critical role in the stabilization of RNA structures. Therefore, accurate prediction of the ion effects in RNA folding can have a far-reaching impact on our understanding of RNA structure and function. Multivalent ions, especially Mg²⁺, are essential for RNA tertiary structure formation. These ions can possibly become strongly correlated in the close vicinity of RNA surface. Most of the currently available software packages, which have widespread success in predicting ion effects in biomolecular systems, however, do not explicitly account for the ion correlation effect. Therefore, it is important to develop a software package/web server for the prediction of ion electrostatics in RNA folding by including ion correlation effects. The TBI web server http://rna.physics.missouri.edu/tbi_index.html provides predictions for the total electrostatic free energy, the different free energy components, and the mean number and the most probable distributions of the bound ions. A novel feature of the TBI server is its ability to account for ion correlation and ion distribution fluctuation effects. By accounting for the ion correlation and fluctuation effects, the TBI server is a unique online tool for computing ion-mediated electrostatic properties for given RNA structures. The results can provide important data for in-depth analysis for ion effects in RNA folding including the ion-dependence of folding stability, ion uptake in the folding process, and the interplay between the different energetic components.

TBI server: a web server for predicting ion effects in RNA folding.

Directory of Open Access Journals (Sweden)

Yuhong Zhu

Full Text Available Metal ions play a critical role in the stabilization of RNA structures. Therefore, accurate prediction of the ion effects in RNA folding can have a far-reaching impact on our understanding of RNA structure and function. Multivalent ions, especially Mg²⁺, are essential for RNA tertiary structure formation. These ions can possibly become strongly correlated in the close vicinity of RNA surface. Most of the currently available software packages, which have widespread success in predicting ion effects in biomolecular systems, however, do not explicitly account for the ion correlation effect. Therefore, it is important to develop a software package/web server for the prediction of ion electrostatics in RNA folding by including ion correlation effects.The TBI web server http://rna.physics.missouri.edu/tbi_index.html provides predictions for the total electrostatic free energy, the different free energy components, and the mean number and the most probable distributions of the bound ions. A novel feature of the TBI server is its ability to account for ion correlation and ion distribution fluctuation effects.By accounting for the ion correlation and fluctuation effects, the TBI server is a unique online tool for computing ion-mediated electrostatic properties for given RNA structures. The results can provide important data for in-depth analysis for ion effects in RNA folding including the ion-dependence of folding stability, ion uptake in the folding process, and the interplay between the different energetic components.

Prepare for X-Win32 - the new X11 server software for Windows computers

CERN Multimedia

IT Department

2011-01-01

Starnet X-Win32 will replace Exceed as the X11 Server software on Windows computers by February 2012. X11 Server software allows a Windows user to have a graphical user interface on a remote Linux server. This change, initially motivated by a significant change of license conditions for Exceed, brings an easier integration of Windows and Linux logon mechanisms. At the same time, X-Win32 addresses the common use cases while providing a more intuitive configuration interface. CERN Predefined Connections will be available as before. They offer an easy way of starting applications on LXPLUS using PuTTY or starting the KDE, GNOME or ICE window managers. Since X-Win32 is better integrated with SSH and CERN Kerberos compared to Exceed, it is much simpler to set up secure access to Linux services. The decision to choose X-Win32 as the new X11 software resulted from an evaluation that involved various user communities and support teams. More information, including the documented use cases, is available at https://...

Using Servers to Enhance Control System Capability

International Nuclear Information System (INIS)

Bickley, M.; Bowling, B. A.; Bryan, D. A.; Zeijts, J. van; White, K. S.; Witherspoon, S.

1999-01-01

Many traditional control systems include a distributed collection of front end machines to control hardware. Backend tools are used to view, modify, and record the signals generated by these front end machines. Software servers, which are a middleware layer between the front and back ends, can improve a control system in several ways. Servers can enable on-line processing of raw data, and consolidation of functionality. It many cases data retrieved from the front end must be processed in order to convert the raw data into useful information. These calculations are often redundantly performance by different programs, frequently offline. Servers can monitor the raw data and rapidly perform calculations, producing new signals which can be treated like any other control system signal, and can be used by any back end application. Algorithms can be incorporated to actively modify signal values in the control system based upon changes of other signals, essentially producing feedback in a control system. Servers thus increase the flexibility of a control system. Lastly, servers running on inexpensive UNIXworkstations can relay or cache frequently needed information, reducing the load on front end hardware by functioning as concentrators. Rather than many back end tools connecting directly to the front end machines, increasing the work load of these machines, they instead connect to the server. Servers like those discussed above have been used successfully at the Thomas Jefferson National Accelerator Facility to provide functionality such as beam steering, fault monitoring, storage of machine parameters, and on-line data processing. The authors discuss the potential uses of such servers, and share the results of work performed to date

CNA web server: rigidity theory-based thermal unfolding simulations of proteins for linking structure, (thermo-)stability, and function.

Science.gov (United States)

Krüger, Dennis M; Rathi, Prakash Chandra; Pfleger, Christopher; Gohlke, Holger

2013-07-01

The Constraint Network Analysis (CNA) web server provides a user-friendly interface to the CNA approach developed in our laboratory for linking results from rigidity analyses to biologically relevant characteristics of a biomolecular structure. The CNA web server provides a refined modeling of thermal unfolding simulations that considers the temperature dependence of hydrophobic tethers and computes a set of global and local indices for quantifying biomacromolecular stability. From the global indices, phase transition points are identified where the structure switches from a rigid to a floppy state; these phase transition points can be related to a protein's (thermo-)stability. Structural weak spots (unfolding nuclei) are automatically identified, too; this knowledge can be exploited in data-driven protein engineering. The local indices are useful in linking flexibility and function and to understand the impact of ligand binding on protein flexibility. The CNA web server robustly handles small-molecule ligands in general. To overcome issues of sensitivity with respect to the input structure, the CNA web server allows performing two ensemble-based variants of thermal unfolding simulations. The web server output is provided as raw data, plots and/or Jmol representations. The CNA web server, accessible at http://cpclab.uni-duesseldorf.de/cna or http://www.cnanalysis.de, is free and open to all users with no login requirement.

Microsoft DirectAccess best practices and troubleshooting

CERN Document Server

Krause, Jordan

2013-01-01

This book covers best practices and acts as a complete guide to DirectAccess and automatic remote access.Microsoft DirectAccess Best Practices and Troubleshooting is an ideal guide for any existing or future DirectAccess administrator and system administrators who are working on Windows Server 2012. This book will also be beneficial for someone with a basic knowledge of networking and deployment of Microsoft operating systems and software who wants to learn the intricacies of DirectAccess and its interfaces.

FUn: a framework for interactive visualizations of large, high-dimensional datasets on the web.

Science.gov (United States)

Probst, Daniel; Reymond, Jean-Louis

2018-04-15

During the past decade, big data have become a major tool in scientific endeavors. Although statistical methods and algorithms are well-suited for analyzing and summarizing enormous amounts of data, the results do not allow for a visual inspection of the entire data. Current scientific software, including R packages and Python libraries such as ggplot2, matplotlib and plot.ly, do not support interactive visualizations of datasets exceeding 100 000 data points on the web. Other solutions enable the web-based visualization of big data only through data reduction or statistical representations. However, recent hardware developments, especially advancements in graphical processing units, allow for the rendering of millions of data points on a wide range of consumer hardware such as laptops, tablets and mobile phones. Similar to the challenges and opportunities brought to virtually every scientific field by big data, both the visualization of and interaction with copious amounts of data are both demanding and hold great promise. Here we present FUn, a framework consisting of a client (Faerun) and server (Underdark) module, facilitating the creation of web-based, interactive 3D visualizations of large datasets, enabling record level visual inspection. We also introduce a reference implementation providing access to SureChEMBL, a database containing patent information on more than 17 million chemical compounds. The source code and the most recent builds of Faerun and Underdark, Lore.js and the data preprocessing toolchain used in the reference implementation, are available on the project website (http://doc.gdb.tools/fun/). daniel.probst@dcb.unibe.ch or jean-louis.reymond@dcb.unibe.ch.

Server-Aided Verification Signature with Privacy for Mobile Computing

Directory of Open Access Journals (Sweden)

Lingling Xu

2015-01-01

Full Text Available With the development of wireless technology, much data communication and processing has been conducted in mobile devices with wireless connection. As we know that the mobile devices will always be resource-poor relative to static ones though they will improve in absolute ability, therefore, they cannot process some expensive computational tasks due to the constrained computational resources. According to this problem, server-aided computing has been studied in which the power-constrained mobile devices can outsource some expensive computation to a server with powerful resources in order to reduce their computational load. However, in existing server-aided verification signature schemes, the server can learn some information about the message-signature pair to be verified, which is undesirable especially when the message includes some secret information. In this paper, we mainly study the server-aided verification signatures with privacy in which the message-signature pair to be verified can be protected from the server. Two definitions of privacy for server-aided verification signatures are presented under collusion attacks between the server and the signer. Then based on existing signatures, two concrete server-aided verification signature schemes with privacy are proposed which are both proved secure.

PIQMIe: a web server for semi-quantitative proteomics data management and analysis.

Science.gov (United States)

Kuzniar, Arnold; Kanaar, Roland

2014-07-01

We present the Proteomics Identifications and Quantitations Data Management and Integration Service or PIQMIe that aids in reliable and scalable data management, analysis and visualization of semi-quantitative mass spectrometry based proteomics experiments. PIQMIe readily integrates peptide and (non-redundant) protein identifications and quantitations from multiple experiments with additional biological information on the protein entries, and makes the linked data available in the form of a light-weight relational database, which enables dedicated data analyses (e.g. in R) and user-driven queries. Using the web interface, users are presented with a concise summary of their proteomics experiments in numerical and graphical forms, as well as with a searchable protein grid and interactive visualization tools to aid in the rapid assessment of the experiments and in the identification of proteins of interest. The web server not only provides data access through a web interface but also supports programmatic access through RESTful web service. The web server is available at http://piqmie.semiqprot-emc.cloudlet.sara.nl or http://www.bioinformatics.nl/piqmie. This website is free and open to all users and there is no login requirement. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

Process mining in oncology using the MIMIC-III dataset

Science.gov (United States)

Prima Kurniati, Angelina; Hall, Geoff; Hogg, David; Johnson, Owen

2018-03-01

Process mining is a data analytics approach to discover and analyse process models based on the real activities captured in information systems. There is a growing body of literature on process mining in healthcare, including oncology, the study of cancer. In earlier work we found 37 peer-reviewed papers describing process mining research in oncology with a regular complaint being the limited availability and accessibility of datasets with suitable information for process mining. Publicly available datasets are one option and this paper describes the potential to use MIMIC-III, for process mining in oncology. MIMIC-III is a large open access dataset of de-identified patient records. There are 134 publications listed as using the MIMIC dataset, but none of them have used process mining. The MIMIC-III dataset has 16 event tables which are potentially useful for process mining and this paper demonstrates the opportunities to use MIMIC-III for process mining in oncology. Our research applied the L* lifecycle method to provide a worked example showing how process mining can be used to analyse cancer pathways. The results and data quality limitations are discussed along with opportunities for further work and reflection on the value of MIMIC-III for reproducible process mining research.

Web server's reliability improvements using recurrent neural networks

DEFF Research Database (Denmark)

Madsen, Henrik; Albu, Rǎzvan-Daniel; Felea, Ioan

2012-01-01

In this paper we describe an interesting approach to error prediction illustrated by experimental results. The application consists of monitoring the activity for the web servers in order to collect the specific data. Predicting an error with severe consequences for the performance of a server (t...... usage, network usage and memory usage. We collect different data sets from monitoring the web server's activity and for each one we predict the server's reliability with the proposed recurrent neural network. © 2012 Taylor & Francis Group...

DNA barcode goes two-dimensions: DNA QR code web server.

Science.gov (United States)

Liu, Chang; Shi, Linchun; Xu, Xiaolan; Li, Huan; Xing, Hang; Liang, Dong; Jiang, Kun; Pang, Xiaohui; Song, Jingyuan; Chen, Shilin

2012-01-01

The DNA barcoding technology uses a standard region of DNA sequence for species identification and discovery. At present, "DNA barcode" actually refers to DNA sequences, which are not amenable to information storage, recognition, and retrieval. Our aim is to identify the best symbology that can represent DNA barcode sequences in practical applications. A comprehensive set of sequences for five DNA barcode markers ITS2, rbcL, matK, psbA-trnH, and CO1 was used as the test data. Fifty-three different types of one-dimensional and ten two-dimensional barcode symbologies were compared based on different criteria, such as coding capacity, compression efficiency, and error detection ability. The quick response (QR) code was found to have the largest coding capacity and relatively high compression ratio. To facilitate the further usage of QR code-based DNA barcodes, a web server was developed and is accessible at http://qrfordna.dnsalias.org. The web server allows users to retrieve the QR code for a species of interests, convert a DNA sequence to and from a QR code, and perform species identification based on local and global sequence similarities. In summary, the first comprehensive evaluation of various barcode symbologies has been carried out. The QR code has been found to be the most appropriate symbology for DNA barcode sequences. A web server has also been constructed to allow biologists to utilize QR codes in practical DNA barcoding applications.

DNA barcode goes two-dimensions: DNA QR code web server.

Directory of Open Access Journals (Sweden)

Chang Liu

Full Text Available The DNA barcoding technology uses a standard region of DNA sequence for species identification and discovery. At present, "DNA barcode" actually refers to DNA sequences, which are not amenable to information storage, recognition, and retrieval. Our aim is to identify the best symbology that can represent DNA barcode sequences in practical applications. A comprehensive set of sequences for five DNA barcode markers ITS2, rbcL, matK, psbA-trnH, and CO1 was used as the test data. Fifty-three different types of one-dimensional and ten two-dimensional barcode symbologies were compared based on different criteria, such as coding capacity, compression efficiency, and error detection ability. The quick response (QR code was found to have the largest coding capacity and relatively high compression ratio. To facilitate the further usage of QR code-based DNA barcodes, a web server was developed and is accessible at http://qrfordna.dnsalias.org. The web server allows users to retrieve the QR code for a species of interests, convert a DNA sequence to and from a QR code, and perform species identification based on local and global sequence similarities. In summary, the first comprehensive evaluation of various barcode symbologies has been carried out. The QR code has been found to be the most appropriate symbology for DNA barcode sequences. A web server has also been constructed to allow biologists to utilize QR codes in practical DNA barcoding applications.

An Improvement of Robust Biometrics-Based Authentication and Key Agreement Scheme for Multi-Server Environments Using Smart Cards

Science.gov (United States)

Moon, Jongho; Choi, Younsung; Jung, Jaewook; Won, Dongho

2015-01-01

In multi-server environments, user authentication is a very important issue because it provides the authorization that enables users to access their data and services; furthermore, remote user authentication schemes for multi-server environments have solved the problem that has arisen from user’s management of different identities and passwords. For this reason, numerous user authentication schemes that are designed for multi-server environments have been proposed over recent years. In 2015, Lu et al. improved upon Mishra et al.’s scheme, claiming that their remote user authentication scheme is more secure and practical; however, we found that Lu et al.’s scheme is still insecure and incorrect. In this paper, we demonstrate that Lu et al.’s scheme is vulnerable to outsider attack and user impersonation attack, and we propose a new biometrics-based scheme for authentication and key agreement that can be used in multi-server environments; then, we show that our proposed scheme is more secure and supports the required security properties. PMID:26709702

Windows Terminal Servers Orchestration

Science.gov (United States)

Bukowiec, Sebastian; Gaspar, Ricardo; Smith, Tim

2017-10-01

Windows Terminal Servers provide application gateways for various parts of the CERN accelerator complex, used by hundreds of CERN users every day. The combination of new tools such as Puppet, HAProxy and Microsoft System Center suite enable automation of provisioning workflows to provide a terminal server infrastructure that can scale up and down in an automated manner. The orchestration does not only reduce the time and effort necessary to deploy new instances, but also facilitates operations such as patching, analysis and recreation of compromised nodes as well as catering for workload peaks.

The RNAsnp web server

DEFF Research Database (Denmark)

Radhakrishnan, Sabarinathan; Tafer, Hakim; Seemann, Ernst Stefan

2013-01-01

, are derived from extensive pre-computed tables of distributions of substitution effects as a function of gene length and GC content. Here, we present a web service that not only provides an interface for RNAsnp but also features a graphical output representation. In addition, the web server is connected...... to a local mirror of the UCSC genome browser database that enables the users to select the genomic sequences for analysis and visualize the results directly in the UCSC genome browser. The RNAsnp web server is freely available at: http://rth.dk/resources/rnasnp/....

Optimizing queries in SQL Server 2008

Directory of Open Access Journals (Sweden)

Ion LUNGU

2010-05-01

Full Text Available Starting from the need to develop efficient IT systems, we intend to review theoptimization methods and tools that can be used by SQL Server database administratorsand developers of applications based on Microsoft technology, focusing on the latestversion of the proprietary DBMS, SQL Server 2008. We’ll reflect on the objectives tobe considered in improving the performance of SQL Server instances, we will tackle themostly used techniques for analyzing and optimizing queries and we will describe the“Optimize for ad hoc workloads”, “Plan Freezing” and “Optimize for unknown" newoptions, accompanied by relevant code examples.

Publishing datasets with eSciDoc and panMetaDocs

Science.gov (United States)

Ulbricht, D.; Klump, J.; Bertelmann, R.

2012-04-01

Currently serveral research institutions worldwide undertake considerable efforts to have their scientific datasets published and to syndicate them to data portals as extensively described objects identified by a persistent identifier. This is done to foster the reuse of data, to make scientific work more transparent, and to create a citable entity that can be referenced unambigously in written publications. GFZ Potsdam established a publishing workflow for file based research datasets. Key software components are an eSciDoc infrastructure [1] and multiple instances of the data curation tool panMetaDocs [2]. The eSciDoc repository holds data objects and their associated metadata in container objects, called eSciDoc items. A key metadata element in this context is the publication status of the referenced data set. PanMetaDocs, which is based on PanMetaWorks [3], is a PHP based web application that allows to describe data with any XML-based metadata schema. The metadata fields can be filled with static or dynamic content to reduce the number of fields that require manual entries to a minimum and make use of contextual information in a project setting. Access rights can be applied to set visibility of datasets to other project members and allow collaboration on and notifying about datasets (RSS) and interaction with the internal messaging system, that was inherited from panMetaWorks. When a dataset is to be published, panMetaDocs allows to change the publication status of the eSciDoc item from status "private" to "submitted" and prepare the dataset for verification by an external reviewer. After quality checks, the item publication status can be changed to "published". This makes the data and metadata available through the internet worldwide. PanMetaDocs is developed as an eSciDoc application. It is an easy to use graphical user interface to eSciDoc items, their data and metadata. It is also an application supporting a DOI publication agent during the process of

The CAD-score web server: contact area-based comparison of structures and interfaces of proteins, nucleic acids and their complexes.

Science.gov (United States)

Olechnovič, Kliment; Venclovas, Ceslovas

2014-07-01

The Contact Area Difference score (CAD-score) web server provides a universal framework to compute and analyze discrepancies between different 3D structures of the same biological macromolecule or complex. The server accepts both single-subunit and multi-subunit structures and can handle all the major types of macromolecules (proteins, RNA, DNA and their complexes). It can perform numerical comparison of both structures and interfaces. In addition to entire structures and interfaces, the server can assess user-defined subsets. The CAD-score server performs both global and local numerical evaluations of structural differences between structures or interfaces. The results can be explored interactively using sortable tables of global scores, profiles of local errors, superimposed contact maps and 3D structure visualization. The web server could be used for tasks such as comparison of models with the native (reference) structure, comparison of X-ray structures of the same macromolecule obtained in different states (e.g. with and without a bound ligand), analysis of nuclear magnetic resonance (NMR) structural ensemble or structures obtained in the course of molecular dynamics simulation. The web server is freely accessible at: http://www.ibt.lt/bioinformatics/cad-score. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

NEOview: Near Earth Object Data Discovery and Query

Science.gov (United States)

Tibbetts, M.; Elvis, M.; Galache, J. L.; Harbo, P.; McDowell, J. C.; Rudenko, M.; Van Stone, D.; Zografou, P.

2013-10-01

Missions to Near Earth Objects (NEOs) figure prominently in NASA's Flexible Path approach to human space exploration. NEOs offer insight into both the origins of the Solar System and of life, as well as a source of materials for future missions. With NEOview scientists can locate NEO datasets, explore metadata provided by the archives, and query or combine disparate NEO datasets in the search for NEO candidates for exploration. NEOview is a software system that illustrates how standards-based interfaces facilitate NEO data discovery and research. NEOview software follows a client-server architecture. The server is a configurable implementation of the International Virtual Observatory Alliance (IVOA) Table Access Protocol (TAP), a general interface for tabular data access, that can be deployed as a front end to existing NEO datasets. The TAP client, seleste, is a graphical interface that provides intuitive means of discovering NEO providers, exploring dataset metadata to identify fields of interest, and constructing queries to retrieve or combine data. It features a powerful, graphical query builder capable of easing the user's introduction to table searches. Through science use cases, NEOview demonstrates how potential targets for NEO rendezvous could be identified by combining data from complementary sources. Through deployment and operations, it has been shown that the software components are data independent and configurable to many different data servers. As such, NEOview's TAP server and seleste TAP client can be used to create a seamless environment for data discovery and exploration for tabular data in any astronomical archive.

Creation of an online multimedia radiology module access to Internet

International Nuclear Information System (INIS)

Alejo, J.P.; Vega, J.M.; Perez, R.

1996-01-01

Using freely distributed programs, we have created a radiology data server in the world wide web (WWW) system, which includes among its services a radiological teaching module developed entirely in Spanish. This server is linked to Internet, the extensive worldwide computer network, to which WWW subscribers have access. The data is presented in hypertext and hypermedia format. (Author) 9 refs

Informatics in Radiology (infoRAD): mobile wireless DICOM server system and PDA with high-resolution display: feasibility of group work for radiologists.

Science.gov (United States)

Nakata, Norio; Kandatsu, Susumu; Suzuki, Naoki; Fukuda, Kunihiko

2005-01-01

A novel mobile system has been developed for use by radiologists in managing Digital Imaging and Communications in Medicine (DICOM) image data. The system consists of a mobile DICOM server (MDS) and personal digital assistants (PDAs), including a Linux PDA with a video graphics array (VGA) display (307,200 pixels, 3.7 inches). The MDS weighs 410 g, has a 60-GB hard disk drive and a built-in wireless local area network (LAN) access point, and supports a DICOM server (Central Test Node). The Linux-based MDS can be accessed with personal computers (PCs) and PDAs by means of a wireless or wired LAN, and client-server communications can be established at any time. DICOM images can be displayed by using any PDA or PC by means of a Web browser. Simultaneous access to the MDS is possible for multiple authenticated users. With most PDAs, image compression is necessary for complete display of DICOM images; however, the VGA screen can display a 512 x 512-pixel DICOM image almost in its entirety. This wireless system allows efficient management of heavy loads of lossless DICOM image data and will be useful for collaborative work by radiologists in education, conferences, and research.

Experience with Server Self Service Center (S3C)

International Nuclear Information System (INIS)

Sucik, Juraj; Bukowiec, Sebastian

2010-01-01

CERN has a successful experience with running Server Self Service Center (S3C) for virtual server provisioning which is based on Microsoft (registered) Virtual Server 2005. With the introduction of Windows Server 2008 and its built-in hypervisor based virtualization (Hyper-V) there are new possibilities for the expansion of the current service. This paper describes the architecture of the redesigned virtual Server Self Service based on Hyper-V which provides dynamically scalable virtualized resources on demand as needed and outlines the possible implications on the future use of virtual machines at CERN.

Experience with Server Self Service Center (S3C)

CERN Multimedia

Sucik, J

2009-01-01

CERN has a successful experience with running Server Self Service Center (S3C) for virtual server provisioning which is based on Microsoft® Virtual Server 2005. With the introduction of Windows Server 2008 and its built-in hypervisor based virtualization (Hyper-V) there are new possibilities for the expansion of the current service. This paper describes the architecture of the redesigned virtual Server Self Service based on Hyper-V which provides dynamically scalable virtualized resources on demand as needed and outlines the possible implications on the future use of virtual machines at CERN.

Energy Efficiency in Small Server Rooms: Field Surveys and Findings

Energy Technology Data Exchange (ETDEWEB)

Cheung, Iris [Hoi; Greenberg, Steve; Mahdavi, Roozbeh; Brown, Richard; Tschudi, William

2014-08-11

Fifty-seven percent of US servers are housed in server closets, server rooms, and localized data centers, in what are commonly referred to as small server rooms, which comprise 99percent of all server spaces in the US. While many mid-tier and enterprise-class data centers are owned by large corporations that consider energy efficiency a goal to minimize business operating costs, small server rooms typically are not similarly motivated. They are characterized by decentralized ownership and management and come in many configurations, which creates a unique set of efficiency challenges. To develop energy efficiency strategies for these spaces, we surveyed 30 small server rooms across eight institutions, and selected four of them for detailed assessments. The four rooms had Power Usage Effectiveness (PUE) values ranging from 1.5 to 2.1. Energy saving opportunities ranged from no- to low-cost measures such as raising cooling set points and better airflow management, to more involved but cost-effective measures including server consolidation and virtualization, and dedicated cooling with economizers. We found that inefficiencies mainly resulted from organizational rather than technical issues. Because of the inherent space and resource limitations, the most effective measure is to operate servers through energy-efficient cloud-based services or well-managed larger data centers, rather than server rooms. Backup power requirement, and IT and cooling efficiency should be evaluated to minimize energy waste in the server space. Utility programs are instrumental in raising awareness and spreading technical knowledge on server operation, and the implementation of energy efficiency measures in small server rooms.

Server-Aided Two-Party Computation with Simultaneous Corruption

DEFF Research Database (Denmark)

Cascudo Pueyo, Ignacio; Damgård, Ivan Bjerre; Ranellucci, Samuel

We consider secure two-party computation in the client-server model where there are two adversaries that operate separately but simultaneously, each of them corrupting one of the parties and a restricted subset of servers that they interact with. We model security via the local universal composab......We consider secure two-party computation in the client-server model where there are two adversaries that operate separately but simultaneously, each of them corrupting one of the parties and a restricted subset of servers that they interact with. We model security via the local universal...

Cluster Server IPTV dengan Penjadwalan Algoritma Round Robin

Directory of Open Access Journals (Sweden)

Didik Aribowo

2016-03-01

Full Text Available Perkembangan teknologi informasi yang pesat, otomatis seiring juga dengan meningkatnya para pengguna yang terhubung pada jaringan internet. Berawal dari sebuah single server yang selalu mendapatkan request dari banyak user, perlahan tapi pasti akan terjadi overload dan crash sehingga berdampak pada request yang tidak dapat dilayani oleh single server. Desain arsitektur cluster dapat dibangun dengan menggunakan konsep network load balancing yang memungkinkan proses pengolahan data di share ke dalam beberapa komputer. Dalam penelitian ini menggunakan algoritma penjadwalan round robin sebagai solusi alternatif mengatasi permasalah overload data pada server yang dapat mempengaruhi kinerja sistem IPTV. Untuk  jumlah request yang digunakan dalam penelitian ini adalah 5000, 15000, 25000, dan 50000 request. Dengan metode tersebut, maka performansi algoritma penjawalan dapat diamati dengan menekankan pada parameter sebagai berikut, yaitu throughput, respon time, reply connection, dan error connection sehingga didapatkan algoritma penjadwalan terbaik dalam rangka optimalisasi cluster server IPTV. Secara otomatis dalam proses load balancing mampu mengurangi beban kerja setiap server sehingga tidak ada server yang overload dan memungkinkan server  menggunakan bandwidth  yang tersedia secara lebih efektif serta menyediakan akses yang cepat ke web browser yang dihosting. Implementasi webserver cluster dengan skema load balancing dapat memberikan alvalaibilitas sistem yang tetap terjaga dan skalabilitas yang cukup untuk dapat tetap melayani setiap request dari pengguna

Environmental Research Division's Data Access Program (ERDDAP)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — ERDDAP (the Environmental Research Division's Data Access Program) is a data server that gives you a simple, consistent way to download subsets of scientific...

基于ENSP的NAPT和NAT Server的实现%Implementation of NAPT and NAT Server Based on ENSP

Institute of Scientific and Technical Information of China (English)

王崇; 陈燕

2016-01-01

为了解决IP地址紧缺以及局域网安全的问题，提出一种NAPT网络设计。公司总部和分公司的内部网络分别通过一个映射到公网的IP地址实现网络通信。公司的私网通常会有一些服务器需要提供给公网用户访问。但网络部署时，服务器地址一般都会被配置成私网地址，这样服务器就不能直接使用自身的地址来提供服务了[1]。因此在路由器上配置NAT Server，通过公布到公网的IP地址来访问内部的服务器。此实现方案，为相关网络实践提供了有益的参考。%In order to solve problems of IP address scarcity and local area network security, a NAPT network design is then proposed. Internal networks of headquarter company and its subsidiaries can achieved network communications through respectively mapping to a public IP address. Some servers in the private network of a company usually have to provide public-network subscribers with access. But in network deployment, the server address will often be configured to a private one, and then the server cannot provide services through direct use of its own address[1]. In such a situation, however, it can gain access to internal servers through the IP address released on public network by configuring NAT Server in the router. This implementation plan has rendered a valuable reference to relevant network practices.

SMPBS: Web server for computing biomolecular electrostatics using finite element solvers of size modified Poisson-Boltzmann equation.

Science.gov (United States)

Xie, Yang; Ying, Jinyong; Xie, Dexuan

2017-03-30

SMPBS (Size Modified Poisson-Boltzmann Solvers) is a web server for computing biomolecular electrostatics using finite element solvers of the size modified Poisson-Boltzmann equation (SMPBE). SMPBE not only reflects ionic size effects but also includes the classic Poisson-Boltzmann equation (PBE) as a special case. Thus, its web server is expected to have a broader range of applications than a PBE web server. SMPBS is designed with a dynamic, mobile-friendly user interface, and features easily accessible help text, asynchronous data submission, and an interactive, hardware-accelerated molecular visualization viewer based on the 3Dmol.js library. In particular, the viewer allows computed electrostatics to be directly mapped onto an irregular triangular mesh of a molecular surface. Due to this functionality and the fast SMPBE finite element solvers, the web server is very efficient in the calculation and visualization of electrostatics. In addition, SMPBE is reconstructed using a new objective electrostatic free energy, clearly showing that the electrostatics and ionic concentrations predicted by SMPBE are optimal in the sense of minimizing the objective electrostatic free energy. SMPBS is available at the URL: smpbs.math.uwm.edu © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Access 2013 all-in-one for dummies

CERN Document Server

Barrows, Alison; Taylor, Allen G

2013-01-01

Get started with the new Access 2013 with this impressive all-in-one reference! Microsoft Access allows you to store, organize, view, analyze, and share data; the new release enables you to build even more powerful, custom database solutions that integrate with the web and enterprise data sources. This compilation of nine indispensible minibooks is exactly what you need to get up to speed on the latest changes to Access. This easy-to-understand resource provides both new and experienced Access users with invaluable advice for connecting Access to SQL Server, manipulating data local

Maintenance in Single-Server Queues: A Game-Theoretic Approach

Directory of Open Access Journals (Sweden)

Najeeb Al-Matar

2009-01-01

examine a single-server queue with bulk input and secondary work during server's multiple vacations. When the buffer contents become exhausted the server leaves the system to perform some diagnostic service of a minimum of L jobs clustered in packets of random sizes (event A. The server is not supposed to stay longer than T units of time (event B. The server returns to the system when A or B occurs, whichever comes first. On the other hand, he may not break service of a packet in a middle even if A or B occurs. Furthermore, the server waits for batches of customers to arrive if upon his return the queue is still empty. We obtain a compact and explicit form functional for the queueing process in equilibrium.

Locating Nearby Copies of Replicated Internet Servers

National Research Council Canada - National Science Library

Guyton, James D; Schwartz, Michael F

1995-01-01

In this paper we consider the problem of choosing among a collection of replicated servers focusing on the question of how to make choices that segregate client/server traffic according to network topology...

GeoServer beginner's guide

CERN Document Server

Youngblood, Brian

2013-01-01

Step-by-step instructions are included and the needs of a beginner are totally satisfied by the book. The book consists of plenty of examples with accompanying screenshots and code for an easy learning curve. You are a web developer with knowledge of server side scripting, and have experience with installing applications on the server. You have a desire to want more than Google maps, by offering dynamically built maps on your site with your latest geospatial data stored in MySQL, PostGIS, MsSQL or Oracle. If this is the case, this book is meant for you.

Server hardware trends

CERN Multimedia

CERN. Geneva

2014-01-01

This talk will cover the status of the current and upcoming offers on server platforms, focusing mainly on the processing and storage parts. Alternative solutions like Open Compute (OCP) will be quickly covered.

On-line single server dial-a-ride problems

NARCIS (Netherlands)

Feuerstein, E.; Stougie, L.

1998-01-01

In this paper results on the dial-a-ride problem with a single server are presented. Requests for rides consist of two points in a metric space, a source and a destination. A ride has to be made by the server from the source to the destination. The server travels at unit speed in the metric space

Securing SQL Server Protecting Your Database from Attackers

CERN Document Server

Cherry, Denny

2011-01-01

There is a lot at stake for administrators taking care of servers, since they house sensitive data like credit cards, social security numbers, medical records, and much more. In Securing SQL Server you will learn about the potential attack vectors that can be used to break into your SQL Server database, and how to protect yourself from these attacks. Written by a Microsoft SQL Server MVP, you will learn how to properly secure your database, from both internal and external threats. Best practices and specific tricks employed by the author will also be revealed. Learn expert techniques to protec

Web Server Configuration for an Academic Intranet

National Research Council Canada - National Science Library

Baltzis, Stamatios

2000-01-01

.... One of the factors that boosted this ability was the evolution of the Web Servers. Using the web server technology man can be connected and exchange information with the most remote places all over the...

Implementation of SRPT Scheduling in Web Servers

National Research Council Canada - National Science Library

Harchol-Balter, Mor

2000-01-01

.... Experiments use the Linux operating system and the Flash web server. All experiments are repeated under a range of server loads and under both trace-based workloads and those generated by a Web workload generator...

NOAA Operational Model Archive Distribution System (NOMADS): High Availability Applications for Reliable Real Time Access to Operational Model Data

Science.gov (United States)

Alpert, J. C.; Wang, J.

2009-12-01

To reduce the impact of natural hazards and environmental changes, the National Centers for Environmental Prediction (NCEP) provide first alert and a preferred partner for environmental prediction services, and represents a critical national resource to operational and research communities affected by climate, weather and water. NOMADS is now delivering high availability services as part of NOAA’s official real time data dissemination at its Web Operations Center (WOC) server. The WOC is a web service used by organizational units in and outside NOAA, and acts as a data repository where public information can be posted to a secure and scalable content server. A goal is to foster collaborations among the research and education communities, value added retailers, and public access for science and development efforts aimed at advancing modeling and GEO-related tasks. The user (client) executes what is efficient to execute on the client and the server efficiently provides format independent access services. Client applications can execute on the server, if it is desired, but the same program can be executed on the client side with no loss of efficiency. In this way this paradigm lends itself to aggregation servers that act as servers of servers listing, searching catalogs of holdings, data mining, and updating information from the metadata descriptions that enable collections of data in disparate places to be simultaneously accessed, with results processed on servers and clients to produce a needed answer. The services used to access the operational model data output are the Open-source Project for a Network Data Access Protocol (OPeNDAP), implemented with the Grid Analysis and Display System (GrADS) Data Server (GDS), and applications for slicing, dicing and area sub-setting the large matrix of real time model data holdings. This approach insures an efficient use of computer resources because users transmit/receive only the data necessary for their tasks including

Tandem queue with server slow-down

NARCIS (Netherlands)

Miretskiy, D.I.; Scheinhardt, W.R.W.; Mandjes, M.R.H.

2007-01-01

We study how rare events happen in the standard two-node tandem Jackson queue and in a generalization, the socalled slow-down network, see [2]. In the latter model the service rate of the first server depends on the number of jobs in the second queue: the first server slows down if the amount of

Environment server. Digital field information archival technology

International Nuclear Information System (INIS)

Kita, Nobuyuki; Kita, Yasuyo; Yang, Hai-quan

2002-01-01

For the safety operation of nuclear power plants, it is important to store various information about plants for a long period and visualize those stored information as desired. The system called Environment Server is developed for realizing it. In this paper, the general concepts of Environment Server is explained and its partial implementation for archiving the image information gathered by inspection mobile robots into virtual world and visualizing them is described. An extension of Environment Server for supporting attention sharing is also briefly introduced. (author)

Using Multiple Big Datasets and Machine Learning to Produce a New Global Particulate Dataset: A Technology Challenge Case Study

Science.gov (United States)

Lary, D. J.

2013-12-01

A BigData case study is described where multiple datasets from several satellites, high-resolution global meteorological data, social media and in-situ observations are combined using machine learning on a distributed cluster using an automated workflow. The global particulate dataset is relevant to global public health studies and would not be possible to produce without the use of the multiple big datasets, in-situ data and machine learning.To greatly reduce the development time and enhance the functionality a high level language capable of parallel processing has been used (Matlab). A key consideration for the system is high speed access due to the large data volume, persistence of the large data volumes and a precise process time scheduling capability.

Implementasi Cluster Server pada Raspberry Pi dengan Menggunakan Metode Load Balancing

Directory of Open Access Journals (Sweden)

Ridho Habi Putra

2016-06-01

Full Text Available Server merupakan bagian penting dalam sebuah layanan didalam jaringan komputer. Peran server dapat menentukan kualitas baik buruknya dari layanan tersebut. Kegagalan dari sebuah server bisa disebabkan oleh beberapa faktor diantaranya kerusakan perangkat keras, sistem jaringan serta aliran listrik. Salah satu solusi untuk mengatasi kegagalan server dalam suatu jaringan komputer adalah dengan melakukan clustering server.  Tujuan dari penelitian ini adalah untuk mengukur kemampuan Raspberry Pi (Raspi digunakan sebagai web server. Raspberry Pi yang digunakan menggunakan Raspberry Pi 2 Model B dengan menggunakan processor ARM Cortex-A7 berjalan pada frekuensi 900MHz dengan memiliki RAM 1GB. Sistem operasi yang digunakan pada Raspberry Pi adalah Linux Debian Wheezy. Konsep penelitian ini menggunakan empat buah perangkat Raspberry Pi dimana dua Raspi digunakan sebagai web server dan dua Raspi lainnya digunakan sebagai penyeimbang beban (Load Balancer serta database server. Metode yang digunakan dalam pembangunan cluster server ini menggunakan metode load balancing, dimana beban server bekerja secara merata di masing-masing node. Pengujian yang diterapkan dengan melakukan perbandingan kinerja dari Raspbery Pi yang menangani lalu lintas data secara tunggal tanpa menggunakan load balancer serta pengujian Raspberry Pi dengan menggunakan load balancer sebagai beban penyeimbang antara anggota cluster server.

A Browser-Server-Based Tele-audiology System That Supports Multiple Hearing Test Modalities.

Science.gov (United States)

Yao, Jianchu Jason; Yao, Daoyuan; Givens, Gregg

2015-09-01

Millions of global citizens suffering from hearing disorders have limited or no access to much needed hearing healthcare. Although tele-audiology presents a solution to alleviate this problem, existing remote hearing diagnosis systems support only pure-tone tests, leaving speech and other test procedures unsolved, due to the lack of software and hardware to enable communication required between audiologists and their remote patients. This article presents a comprehensive remote hearing test system that integrates the two most needed hearing test procedures: a pure-tone audiogram and a speech test. This enhanced system is composed of a Web application server, an embedded smart Internet-Bluetooth(®) (Bluetooth SIG, Kirkland, WA) gateway (or console device), and a Bluetooth-enabled audiometer. Several graphical user interfaces and a relational database are hosted on the application server. The console device has been designed to support the tests and auxiliary communication between the local site and the remote site. The study was conducted at an audiology laboratory. Pure-tone audiogram and speech test results from volunteers tested with this tele-audiology system are comparable with results from the traditional face-to-face approach. This browser-server-based comprehensive tele-audiology offers a flexible platform to expand hearing services to traditionally underserved groups.

Energy-Reduction Offloading Technique for Streaming Media Servers

Directory of Open Access Journals (Sweden)

Yeongpil Cho

2016-01-01

Full Text Available Recent growth in popularity of mobile video services raises a demand for one of the most popular and convenient methods of delivering multimedia data, video streaming. However, heterogeneity of currently existing mobile devices involves an issue of separate video transcoding for each type of mobile devices such as smartphones, tablet PCs, and smart TVs. As a result additional burden comes to media servers, which pretranscode multimedia data for number of clients. Regarding even higher increase of video data in the Internet in the future, the problem of media servers overload is impending. To struggle against the problem an offloading method is introduced in this paper. By the use of SorTube offloading framework video transcoding process is shifted from the centralized media server to the local offloading server. Thus, clients can receive personally customized video stream; meanwhile the overload of centralized servers is reduced.

The Development of Mobile Server for Language Courses

OpenAIRE

Tokumoto, Hiroko; Yoshida, Mitsunobu

2009-01-01

The aim of this paper is to introduce the conceptual design of the mobile server software "MY Server" for language teaching drafted by Tokumoto. It is to report how this software is designed and adopted effectively to Japanese language teaching. Most of the current server systems for education require facilities in a big scale including high-spec server machines, professional administrators, which naturally result in big budget projects that individual teachers or small size schools canno...

Unified Access Architecture for Large-Scale Scientific Datasets

Science.gov (United States)

Karna, Risav

2014-05-01

Data-intensive sciences have to deploy diverse large scale database technologies for data analytics as scientists have now been dealing with much larger volume than ever before. While array databases have bridged many gaps between the needs of data-intensive research fields and DBMS technologies (Zhang 2011), invocation of other big data tools accompanying these databases is still manual and separate the database management's interface. We identify this as an architectural challenge that will increasingly complicate the user's work flow owing to the growing number of useful but isolated and niche database tools. Such use of data analysis tools in effect leaves the burden on the user's end to synchronize the results from other data manipulation analysis tools with the database management system. To this end, we propose a unified access interface for using big data tools within large scale scientific array database using the database queries themselves to embed foreign routines belonging to the big data tools. Such an invocation of foreign data manipulation routines inside a query into a database can be made possible through a user-defined function (UDF). UDFs that allow such levels of freedom as to call modules from another language and interface back and forth between the query body and the side-loaded functions would be needed for this purpose. For the purpose of this research we attempt coupling of four widely used tools Hadoop (hadoop1), Matlab (matlab1), R (r1) and ScaLAPACK (scalapack1) with UDF feature of rasdaman (Baumann 98), an array-based data manager, for investigating this concept. The native array data model used by an array-based data manager provides compact data storage and high performance operations on ordered data such as spatial data, temporal data, and matrix-based data for linear algebra operations (scidbusr1). Performances issues arising due to coupling of tools with different paradigms, niche functionalities, separate processes and output

Getting started with SQL Server 2014 administration

CERN Document Server

Ellis, Gethyn

2014-01-01

This is an easytofollow handson tutorial that includes real world examples of SQL Server 2014's new features. Each chapter is explained in a stepbystep manner which guides you to implement the new technology.If you want to create an highly efficient database server then this book is for you. This book is for database professionals and system administrators who want to use the added features of SQL Server 2014 to create a hybrid environment, which is both highly available and allows you to get the best performance from your databases.

Locating Hidden Servers

National Research Council Canada - National Science Library

Oeverlier, Lasse; Syverson, Paul F

2006-01-01

.... Announced properties include server resistance to distributed DoS. Both the EFF and Reporters Without Borders have issued guides that describe using hidden services via Tor to protect the safety of dissidents as well as to resist censorship...

Remote information service access system based on a client-server-service model

Science.gov (United States)

Konrad, A.M.

1996-08-06

A local host computing system, a remote host computing system as connected by a network, and service functionalities: a human interface service functionality, a starter service functionality, and a desired utility service functionality, and a Client-Server-Service (CSS) model is imposed on each service functionality. In one embodiment, this results in nine logical components and three physical components (a local host, a remote host, and an intervening network), where two of the logical components are integrated into one Remote Object Client component, and that Remote Object Client component and the other seven logical components are deployed among the local host and remote host in a manner which eases compatibility and upgrade problems, and provides an illusion to a user that a desired utility service supported on a remote host resides locally on the user`s local host, thereby providing ease of use and minimal software maintenance for users of that remote service. 16 figs.

Karst database development in Minnesota: Design and data assembly

Science.gov (United States)

Gao, Y.; Alexander, E.C.; Tipping, R.G.

2005-01-01

The Karst Feature Database (KFD) of Minnesota is a relational GIS-based Database Management System (DBMS). Previous karst feature datasets used inconsistent attributes to describe karst features in different areas of Minnesota. Existing metadata were modified and standardized to represent a comprehensive metadata for all the karst features in Minnesota. Microsoft Access 2000 and ArcView 3.2 were used to develop this working database. Existing county and sub-county karst feature datasets have been assembled into the KFD, which is capable of visualizing and analyzing the entire data set. By November 17 2002, 11,682 karst features were stored in the KFD of Minnesota. Data tables are stored in a Microsoft Access 2000 DBMS and linked to corresponding ArcView applications. The current KFD of Minnesota has been moved from a Windows NT server to a Windows 2000 Citrix server accessible to researchers and planners through networked interfaces. ?? Springer-Verlag 2005.

Energy-efficient server management; Energieeffizientes Servermanagement

Energy Technology Data Exchange (ETDEWEB)

Sauter, B.

2003-07-01

This final report for the Swiss Federal Office of Energy (SFOE) presents the results of a project that aimed to develop an automatic shut-down system for the servers used in typical electronic data processing installations to be found in small and medium-sized enterprises. The purpose of shutting down these computers - the saving of energy - is discussed. The development of a shutdown unit on the basis of a web-server that automatically shuts down the servers connected to it and then interrupts their power supply is described. The functions of the unit, including pre-set times for switching on and off, remote operation via the Internet and its interaction with clients connected to it are discussed. Examples of the system's user interface are presented.

Distributed Large Dataset Deployment with Improved Load Balancing and Performance

OpenAIRE

Siddharth Bhandari

2016-01-01

Cloud computing is a prototype for permitting universal, appropriate, on-demand network access. Cloud is a method of computing where enormously scalable IT-enabled proficiencies are delivered „as a service‟ using Internet tools to multiple outdoor clients. Virtualization is the establishment of a virtual form of something such as computing device or server, an operating system, or network devices and storage device. The different names for cloud data management are DaaS Data as a ...

GalaxyHomomer: a web server for protein homo-oligomer structure prediction from a monomer sequence or structure.

Science.gov (United States)

Baek, Minkyung; Park, Taeyong; Heo, Lim; Park, Chiwook; Seok, Chaok

2017-07-03

Homo-oligomerization of proteins is abundant in nature, and is often intimately related with the physiological functions of proteins, such as in metabolism, signal transduction or immunity. Information on the homo-oligomer structure is therefore important to obtain a molecular-level understanding of protein functions and their regulation. Currently available web servers predict protein homo-oligomer structures either by template-based modeling using homo-oligomer templates selected from the protein structure database or by ab initio docking of monomer structures resolved by experiment or predicted by computation. The GalaxyHomomer server, freely accessible at http://galaxy.seoklab.org/homomer, carries out template-based modeling, ab initio docking or both depending on the availability of proper oligomer templates. It also incorporates recently developed model refinement methods that can consistently improve model quality. Moreover, the server provides additional options that can be chosen by the user depending on the availability of information on the monomer structure, oligomeric state and locations of unreliable/flexible loops or termini. The performance of the server was better than or comparable to that of other available methods when tested on benchmark sets and in a recent CASP performed in a blind fashion. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

The ChIP-Seq tools and web server: a resource for analyzing ChIP-seq and other types of genomic data.

Science.gov (United States)

Ambrosini, Giovanna; Dreos, René; Kumar, Sunil; Bucher, Philipp

2016-11-18

ChIP-seq and related high-throughput chromatin profilig assays generate ever increasing volumes of highly valuable biological data. To make sense out of it, biologists need versatile, efficient and user-friendly tools for access, visualization and itegrative analysis of such data. Here we present the ChIP-Seq command line tools and web server, implementing basic algorithms for ChIP-seq data analysis starting with a read alignment file. The tools are optimized for memory-efficiency and speed thus allowing for processing of large data volumes on inexpensive hardware. The web interface provides access to a large database of public data. The ChIP-Seq tools have a modular and interoperable design in that the output from one application can serve as input to another one. Complex and innovative tasks can thus be achieved by running several tools in a cascade. The various ChIP-Seq command line tools and web services either complement or compare favorably to related bioinformatics resources in terms of computational efficiency, ease of access to public data and interoperability with other web-based tools. The ChIP-Seq server is accessible at http://ccg.vital-it.ch/chipseq/ .

Installing and Testing a Server Operating System

Directory of Open Access Journals (Sweden)

Lorentz JÄNTSCHI

2003-08-01

Full Text Available The paper is based on the experience of the author with the FreeBSD server operating system administration on three servers in use under academicdirect.ro domain.The paper describes a set of installation, preparation, and administration aspects of a FreeBSD server.First issue of the paper is the installation procedure of FreeBSD operating system on i386 computer architecture. Discussed problems are boot disks preparation and using, hard disk partitioning and operating system installation using a existent network topology and a internet connection.Second issue is the optimization procedure of operating system, server services installation, and configuration. Discussed problems are kernel and services configuration, system and services optimization.The third issue is about client-server applications. Using operating system utilities calls we present an original application, which allows displaying the system information in a friendly web interface. An original program designed for molecular structure analysis was adapted for systems performance comparisons and it serves for a discussion of Pentium, Pentium II and Pentium III processors computation speed.The last issue of the paper discusses the installation and configuration aspects of dial-in service on a UNIX-based operating system. The discussion includes serial ports, ppp and pppd services configuration, ppp and tun devices using.

Pro SQL Server 2012 relational database design and implementation

CERN Document Server

Davidson, Louis

2012-01-01

Learn effective and scalable database design techniques in a SQL Server environment. Pro SQL Server 2012 Relational Database Design and Implementation covers everything from design logic that business users will understand, all the way to the physical implementation of design in a SQL Server database. Grounded in best practices and a solid understanding of the underlying theory, Louis Davidson shows how to "get it right" in SQL Server database design and lay a solid groundwork for the future use of valuable business data. Gives a solid foundation in best practices and relational theory Covers

Foundations of SQL Server 2008 R2 Business Intelligence

CERN Document Server

Fouche, Guy

2011-01-01

Foundations of SQL Server 2008 R2 Business Intelligence introduces the entire exciting gamut of business intelligence tools included with SQL Server 2008. Microsoft has designed SQL Server 2008 to be more than just a database. It's a complete business intelligence (BI) platform. The database is at its core, and surrounding the core are tools for data mining, modeling, reporting, analyzing, charting, and integration with other enterprise-level software packages. SQL Server 2008 puts an incredible amount of BI functionality at your disposal. But how do you take advantage of it? That's what this

Professional Team Foundation Server 2012

CERN Document Server

Blankenship, Ed; Holliday, Grant; Keller, Brian

2012-01-01

A comprehensive guide to using Microsoft Team Foundation Server 2012 Team Foundation Server has become the leading Microsoft productivity tool for software management, and this book covers what developers need to know to use it effectively. Fully revised for the new features of TFS 2012, it provides developers and software project managers with step-by-step instructions and even assists those who are studying for the TFS 2012 certification exam. You'll find a broad overview of TFS, thorough coverage of core functions, a look at extensibility options, and more, written by Microsoft ins

Professional Team Foundation Server 2010

CERN Document Server

Blankenship, Ed; Holliday, Grant; Keller, Brian

2011-01-01

Authoritative guide to TFS 2010 from a dream team of Microsoft insiders and MVPs!Microsoft Visual Studio Team Foundation Server (TFS) has evolved until it is now an essential tool for Microsoft?s Application Lifestyle Management suite of productivity tools, enabling collaboration within and among software development teams. By 2011, TFS will replace Microsoft?s leading source control system, VisualSourceSafe, resulting in an even greater demand for information about it. Professional Team Foundation Server 2010, written by an accomplished team of Microsoft insiders and Microsoft MVPs, provides

Research on optical access network remote management technology

Science.gov (United States)

Wang, Wayne; Zou, Chen; Luo, Wenyi

2008-11-01

This paper goal is to provide a framework for the remote configuration and management of services for PON (Passive Optical Network) access and fiber access. Also it defines how Auto-Configuration Servers (ACS) in the network can remotely configure, troubleshoot and manage a Passive Optical Network (PON) optical network termination (ONT) with layer 3 capabilities using the CPE WAN management protocol, TR-069.

IBM WebSphere Application Server 80 Administration Guide

CERN Document Server

Robinson, Steve

2011-01-01

IBM WebSphere Application Server 8.0 Administration Guide is a highly practical, example-driven tutorial. You will be introduced to WebSphere Application Server 8.0, and guided through configuration, deployment, and tuning for optimum performance. If you are an administrator who wants to get up and running with IBM WebSphere Application Server 8.0, then this book is not to be missed. Experience with WebSphere and Java would be an advantage, but is not essential.

MARSIS data and simulation exploited using array databases: PlanetServer/EarthServer for sounding radars

Science.gov (United States)

Cantini, Federico; Pio Rossi, Angelo; Orosei, Roberto; Baumann, Peter; Misev, Dimitar; Oosthoek, Jelmer; Beccati, Alan; Campalani, Piero; Unnithan, Vikram

2014-05-01

MARSIS is an orbital synthetic aperture radar for both ionosphere and subsurface sounding on board ESA's Mars Express (Picardi et al. 2005). It transmits electromagnetic pulses centered at 1.8, 3, 4 or 5 MHz that penetrate below the surface and are reflected by compositional and/or structural discontinuities in the subsurface of Mars. MARSIS data are available as a collection of single orbit data files. The availability of tools for a more effective access to such data would greatly ease data analysis and exploitation by the community of users. For this purpose, we are developing a database built on the raster database management system RasDaMan (e.g. Baumann et al., 1994), to be populated with MARSIS data and integrated in the PlanetServer/EarthServer (e.g. Oosthoek et al., 2013; Rossi et al., this meeting) project. The data (and related metadata) are stored in the db for each frequency used by MARSIS radar. The capability of retrieving data belonging to a certain orbit or to multiple orbit on the base of latitute/longitude boundaries is a key requirement of the db design, allowing, besides the "classical" radargram representation of the data, and in area with sufficiently hight orbit density, a 3D data extraction, subset and analysis of subsurface structures. Moreover the use of the OGC WCPS (Web Coverage Processing Service) standard can allow calculations on database query results for multiple echoes and/or subsets of a certain data product. Because of the low directivity of its dipole antenna, MARSIS receives echoes from portions of the surface of Mars that are distant from nadir and can be mistakenly interpreted as subsurface echoes. For this reason, methods have been developed to simulate surface echoes (e.g. Nouvel et al., 2004), to reveal the true origin of an echo through comparison with instrument data. These simulations are usually time-consuming, and so far have been performed either on a case-by-case basis or in some simplified form. A code for

A geospatial database model for the management of remote sensing datasets at multiple spectral, spatial, and temporal scales

Science.gov (United States)

Ifimov, Gabriela; Pigeau, Grace; Arroyo-Mora, J. Pablo; Soffer, Raymond; Leblanc, George

2017-10-01

In this study the development and implementation of a geospatial database model for the management of multiscale datasets encompassing airborne imagery and associated metadata is presented. To develop the multi-source geospatial database we have used a Relational Database Management System (RDBMS) on a Structure Query Language (SQL) server which was then integrated into ArcGIS and implemented as a geodatabase. The acquired datasets were compiled, standardized, and integrated into the RDBMS, where logical associations between different types of information were linked (e.g. location, date, and instrument). Airborne data, at different processing levels (digital numbers through geocorrected reflectance), were implemented in the geospatial database where the datasets are linked spatially and temporally. An example dataset consisting of airborne hyperspectral imagery, collected for inter and intra-annual vegetation characterization and detection of potential hydrocarbon seepage events over pipeline areas, is presented. Our work provides a model for the management of airborne imagery, which is a challenging aspect of data management in remote sensing, especially when large volumes of data are collected.

A polling model with an autonomous server

NARCIS (Netherlands)

de Haan, Roland; Boucherie, Richardus J.; van Ommeren, Jan C.W.

2009-01-01

This paper considers polling systems with an autonomous server that remain at a queue for an exponential amount of time before moving to a next queue incurring a generally distributed switch-over time. The server remains at a queue until the exponential visit time expires, also when the queue

Single-server queues with spatially distributed arrivals

NARCIS (Netherlands)

Kroese, Dirk; Schmidt, Volker

1994-01-01

Consider a queueing system where customers arrive at a circle according to a homogeneous Poisson process. After choosing their positions on the circle, according to a uniform distribution, they wait for a single server who travels on the circle. The server's movement is modelled by a Brownian motion

Evaluation of the Intel Nehalem-EX server processor

CERN Document Server

Jarp, S; Leduc, J; Nowak, A; CERN. Geneva. IT Department

2010-01-01

In this paper we report on a set of benchmark results recently obtained by the CERN openlab by comparing the 4-socket, 32-core Intel Xeon X7560 server with the previous generation 4-socket server, based on the Xeon X7460 processor. The Xeon X7560 processor represents a major change in many respects, especially the memory sub-system, so it was important to make multiple comparisons. In most benchmarks the two 4-socket servers were compared. It should be underlined that both servers represent the “top of the line” in terms of frequency. However, in some cases, it was important to compare systems that integrated the latest processor features, such as QPI links, Symmetric multithreading and over-clocking via Turbo mode, and in such situations the X7560 server was compared to a dual socket L5520 based system with an identical frequency of 2.26 GHz. Before summarizing the results we must stress the fact that benchmarking of modern processors is a very complex affair. One has to control (at least) the following ...

Evolution of the Data Access Protocol in Response to Community Needs

Science.gov (United States)

Gallagher, J.; Caron, J. L.; Davis, E.; Fulker, D.; Heimbigner, D.; Holloway, D.; Howe, B.; Moe, S.; Potter, N.

2012-12-01

Under the aegis of the OPULS (OPeNDAP-Unidata Linked Servers) Project, funded by NOAA, version 2 of OPeNDAP's Data Access Protocol (DAP2) is being updated to version 4. DAP4 is the first major upgrade in almost two decades and will embody three main areas of advancement. First, the data-model extensions developed by the OPULS team focus on three areas: Better support for coverages, access to HDF5 files and access to relational databases. DAP2 support for coverages (defined as a sampled functions) was limited to simple rectangular coverages that work well for (some) model outputs and processed satellite data but that cannot represent trajectories or satellite swath data, for example. We have extended the coverage concept in DAP4 to remove these limitations. These changes are informed by work at Unidata on the Common Data Model and also by the OGC's abstract coverages specification. In a similar vein, we have extended DAP2's support for relations by including the concept of foreign keys, so that tables can be explicitly related to one another. Second, the web interfaces - web services - that provides access to data using via DAP will be more clearly defined and use other (, orthogonal), standards where they are appropriate. An important case is the XML interface, which provides a cleaner way to build other response media types such as JSON and RDF (for metadata) and to build support for Atom, thus simplify the integration of DAP servers with tools that support OpenSearch. Input from the ESIP federation and work performed with IOOS have informed our choices here. Last, DAP4-compliant servers will support richer data-processing capabilities than DAP2, enabling a wider array of server functions that manipulate data before returning values. Two projects currently are exploring just what can be done even with DAP2's server-function model: The MIIC project at LARC and OPULS itself (with work performed at the University of Washington). Both projects have demonstrated that

Single-server blind quantum computation with quantum circuit model

Science.gov (United States)

Zhang, Xiaoqian; Weng, Jian; Li, Xiaochun; Luo, Weiqi; Tan, Xiaoqing; Song, Tingting

2018-06-01

Blind quantum computation (BQC) enables the client, who has few quantum technologies, to delegate her quantum computation to a server, who has strong quantum computabilities and learns nothing about the client's quantum inputs, outputs and algorithms. In this article, we propose a single-server BQC protocol with quantum circuit model by replacing any quantum gate with the combination of rotation operators. The trap quantum circuits are introduced, together with the combination of rotation operators, such that the server is unknown about quantum algorithms. The client only needs to perform operations X and Z, while the server honestly performs rotation operators.

CPU Server

CERN Multimedia

The CERN computer centre has hundreds of racks like these. They are over a million times more powerful than our first computer in the 1960's. This tray is a 'dual-core' server. This means it effectively has two CPUs in it (eg. two of your home computers minimised to fit into a single box). Also note the copper cooling fins, to help dissipate the heat.

A tandem queue with delayed server release

NARCIS (Netherlands)

Nawijn, W.M.

1997-01-01

We consider a tandem queue with two stations. The rst station is an s-server queue with Poisson arrivals and exponential service times. After terminating his service in the rst station, a customer enters the second station to require service at an exponential single server, while in the meantime he

A satellite-driven, client-server hydro-economic model prototype for agricultural water management

Science.gov (United States)

Maneta, Marco; Kimball, John; He, Mingzhu; Payton Gardner, W.

2017-04-01

Anticipating agricultural water demand, land reallocation, and impact on farm revenues associated with different policy or climate constraints is a challenge for water managers and for policy makers. While current integrated decision support systems based on programming methods provide estimates of farmer reaction to external constraints, they have important shortcomings such as the high cost of data collection surveys necessary to calibrate the model, biases associated with inadequate farm sampling, infrequent model updates and recalibration, model overfitting, or their deterministic nature, among other problems. In addition, the administration of water supplies and the generation of policies that promote sustainable agricultural regions depend on more than one bureau or office. Unfortunately, managers from local and regional agencies often use different datasets of variable quality, which complicates coordinated action. To overcome these limitations, we present a client-server, integrated hydro-economic modeling and observation framework driven by satellite remote sensing and other ancillary information from regional monitoring networks. The core of the framework is a stochastic data assimilation system that sequentially ingests remote sensing observations and corrects the parameters of the hydro-economic model at unprecedented spatial and temporal resolutions. An economic model of agricultural production, based on mathematical programming, requires information on crop type and extent, crop yield, crop transpiration and irrigation technology. A regional hydro-climatologic model provides biophysical constraints to an economic model of agricultural production with a level of detail that permits the study of the spatial impact of large- and small-scale water use decisions. Crop type and extent is obtained from the Cropland Data Layer (CDL), which is multi-sensor operational classification of crops maintained by the United States Department of Agriculture. Because

Mining and Utilizing Dataset Relevancy from Oceanographic Dataset Metadata, Usage Metrics, and User Feedback to Improve Data Discovery and Access

Data.gov (United States)

National Aeronautics and Space Administration — We propose to mine and utilize the combination of Earth Science dataset, metadata with usage metrics and user feedback to objectively extract relevance for improved...

Design and implementation of streaming media server cluster based on FFMpeg.

Science.gov (United States)

Zhao, Hong; Zhou, Chun-long; Jin, Bao-zhao

2015-01-01

Poor performance and network congestion are commonly observed in the streaming media single server system. This paper proposes a scheme to construct a streaming media server cluster system based on FFMpeg. In this scheme, different users are distributed to different servers according to their locations and the balance among servers is maintained by the dynamic load-balancing algorithm based on active feedback. Furthermore, a service redirection algorithm is proposed to improve the transmission efficiency of streaming media data. The experiment results show that the server cluster system has significantly alleviated the network congestion and improved the performance in comparison with the single server system.

Design and Implementation of Streaming Media Server Cluster Based on FFMpeg

Science.gov (United States)

Zhao, Hong; Zhou, Chun-long; Jin, Bao-zhao

2015-01-01

Poor performance and network congestion are commonly observed in the streaming media single server system. This paper proposes a scheme to construct a streaming media server cluster system based on FFMpeg. In this scheme, different users are distributed to different servers according to their locations and the balance among servers is maintained by the dynamic load-balancing algorithm based on active feedback. Furthermore, a service redirection algorithm is proposed to improve the transmission efficiency of streaming media data. The experiment results show that the server cluster system has significantly alleviated the network congestion and improved the performance in comparison with the single server system. PMID:25734187

COGNAC: a web server for searching and annotating hydrogen-bonded base interactions in RNA three-dimensional structures.

Science.gov (United States)

Firdaus-Raih, Mohd; Hamdani, Hazrina Yusof; Nadzirin, Nurul; Ramlan, Effirul Ikhwan; Willett, Peter; Artymiuk, Peter J

2014-07-01

Hydrogen bonds are crucial factors that stabilize a complex ribonucleic acid (RNA) molecule's three-dimensional (3D) structure. Minute conformational changes can result in variations in the hydrogen bond interactions in a particular structure. Furthermore, networks of hydrogen bonds, especially those found in tight clusters, may be important elements in structure stabilization or function and can therefore be regarded as potential tertiary motifs. In this paper, we describe a graph theoretical algorithm implemented as a web server that is able to search for unbroken networks of hydrogen-bonded base interactions and thus provide an accounting of such interactions in RNA 3D structures. This server, COGNAC (COnnection tables Graphs for Nucleic ACids), is also able to compare the hydrogen bond networks between two structures and from such annotations enable the mapping of atomic level differences that may have resulted from conformational changes due to mutations or binding events. The COGNAC server can be accessed at http://mfrlab.org/grafss/cognac. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

Rtools: a web server for various secondary structural analyses on single RNA sequences.

Science.gov (United States)

Hamada, Michiaki; Ono, Yukiteru; Kiryu, Hisanori; Sato, Kengo; Kato, Yuki; Fukunaga, Tsukasa; Mori, Ryota; Asai, Kiyoshi

2016-07-08

The secondary structures, as well as the nucleotide sequences, are the important features of RNA molecules to characterize their functions. According to the thermodynamic model, however, the probability of any secondary structure is very small. As a consequence, any tool to predict the secondary structures of RNAs has limited accuracy. On the other hand, there are a few tools to compensate the imperfect predictions by calculating and visualizing the secondary structural information from RNA sequences. It is desirable to obtain the rich information from those tools through a friendly interface. We implemented a web server of the tools to predict secondary structures and to calculate various structural features based on the energy models of secondary structures. By just giving an RNA sequence to the web server, the user can get the different types of solutions of the secondary structures, the marginal probabilities such as base-paring probabilities, loop probabilities and accessibilities of the local bases, the energy changes by arbitrary base mutations as well as the measures for validations of the predicted secondary structures. The web server is available at http://rtools.cbrc.jp, which integrates software tools, CentroidFold, CentroidHomfold, IPKnot, CapR, Raccess, Rchange and RintD. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Automated Computer Access Request System

Science.gov (United States)

Snook, Bryan E.

2010-01-01

The Automated Computer Access Request (AutoCAR) system is a Web-based account provisioning application that replaces the time-consuming paper-based computer-access request process at Johnson Space Center (JSC). Auto- CAR combines rules-based and role-based functionality in one application to provide a centralized system that is easily and widely accessible. The system features a work-flow engine that facilitates request routing, a user registration directory containing contact information and user metadata, an access request submission and tracking process, and a system administrator account management component. This provides full, end-to-end disposition approval chain accountability from the moment a request is submitted. By blending both rules-based and rolebased functionality, AutoCAR has the flexibility to route requests based on a user s nationality, JSC affiliation status, and other export-control requirements, while ensuring a user s request is addressed by either a primary or backup approver. All user accounts that are tracked in AutoCAR are recorded and mapped to the native operating system schema on the target platform where user accounts reside. This allows for future extensibility for supporting creation, deletion, and account management directly on the target platforms by way of AutoCAR. The system s directory-based lookup and day-today change analysis of directory information determines personnel moves, deletions, and additions, and automatically notifies a user via e-mail to revalidate his/her account access as a result of such changes. AutoCAR is a Microsoft classic active server page (ASP) application hosted on a Microsoft Internet Information Server (IIS).

PockDrug-Server: a new web server for predicting pocket druggability on holo and apo proteins.

Science.gov (United States)

Hussein, Hiba Abi; Borrel, Alexandre; Geneix, Colette; Petitjean, Michel; Regad, Leslie; Camproux, Anne-Claude

2015-07-01

Predicting protein pocket's ability to bind drug-like molecules with high affinity, i.e. druggability, is of major interest in the target identification phase of drug discovery. Therefore, pocket druggability investigations represent a key step of compound clinical progression projects. Currently computational druggability prediction models are attached to one unique pocket estimation method despite pocket estimation uncertainties. In this paper, we propose 'PockDrug-Server' to predict pocket druggability, efficient on both (i) estimated pockets guided by the ligand proximity (extracted by proximity to a ligand from a holo protein structure) and (ii) estimated pockets based solely on protein structure information (based on amino atoms that form the surface of potential binding cavities). PockDrug-Server provides consistent druggability results using different pocket estimation methods. It is robust with respect to pocket boundary and estimation uncertainties, thus efficient using apo pockets that are challenging to estimate. It clearly distinguishes druggable from less druggable pockets using different estimation methods and outperformed recent druggability models for apo pockets. It can be carried out from one or a set of apo/holo proteins using different pocket estimation methods proposed by our web server or from any pocket previously estimated by the user. PockDrug-Server is publicly available at: http://pockdrug.rpbs.univ-paris-diderot.fr. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

Construction of a nuclear data server using TCP/IP

Energy Technology Data Exchange (ETDEWEB)

Kawano, Toshihiko; Sakai, Osamu [Kyushu Univ., Fukuoka (Japan)

1997-03-01

We construct a nuclear data server which provides data in the evaluated nuclear data library through the network by means of TCP/IP. The client is not necessarily a user but a computer program. Two examples with a prototype server program are demonstrated, the first is data transfer from the server to a user, and the second is to a computer program. (author)

Access 2010 All-in-One For Dummies

CERN Document Server

Barrows, Alison; Stockman, Joseph C

2010-01-01

The all-in-one reference to all aspects of Microsoft Access 2010. If you want to learn Microsoft Access inside and out, the nine minibooks in this easy-access reference are exactly what you need. Read the book cover to cover, or jump into any of the minibooks for the instruction and topics you need most. Learn how to connect Access to SQL Server, manipulate your data locally, use nifty new features from Office 2010 such as the enhanced Ribbon, create queries and macros like a champ, and much more. From the basics to advanced functions, it's what you need to make Access more accesssible.:; Show

BIPS: BIANA Interolog Prediction Server. A tool for protein-protein interaction inference.

Science.gov (United States)

Garcia-Garcia, Javier; Schleker, Sylvia; Klein-Seetharaman, Judith; Oliva, Baldo

2012-07-01

Protein-protein interactions (PPIs) play a crucial role in biology, and high-throughput experiments have greatly increased the coverage of known interactions. Still, identification of complete inter- and intraspecies interactomes is far from being complete. Experimental data can be complemented by the prediction of PPIs within an organism or between two organisms based on the known interactions of the orthologous genes of other organisms (interologs). Here, we present the BIANA (Biologic Interactions and Network Analysis) Interolog Prediction Server (BIPS), which offers a web-based interface to facilitate PPI predictions based on interolog information. BIPS benefits from the capabilities of the framework BIANA to integrate the several PPI-related databases. Additional metadata can be used to improve the reliability of the predicted interactions. Sensitivity and specificity of the server have been calculated using known PPIs from different interactomes using a leave-one-out approach. The specificity is between 72 and 98%, whereas sensitivity varies between 1 and 59%, depending on the sequence identity cut-off used to calculate similarities between sequences. BIPS is freely accessible at http://sbi.imim.es/BIPS.php.

APLIKASI SERVER VIRTUAL IP UNTUK MIKROKONTROLER

OpenAIRE

Ashari, Ahmad

2008-01-01

Selama ini mikrokontroler yang terhubung ke satu komputer hanya dapat diakses melalui satu IP saja, padahal kebanyakan sistem operasi sekarang dapat memperjanjikan lebih dari satu IP untuk setiap komputer dalam bentuk virtual IP. Penelitian ini mengkaji pemanfaatan virtual IP dari IP aliasing pada sistem operasi Linux sebagai Server Virtual IP untuk mikrokontroler. Prinsip dasar Server Virtual IP adalah pembuatan Virtual Host pada masing-masing IP untuk memproses paket-paket data dan menerjem...

LiveBench-1: continuous benchmarking of protein structure prediction servers.

Science.gov (United States)

Bujnicki, J M; Elofsson, A; Fischer, D; Rychlewski, L

2001-02-01

We present a novel, continuous approach aimed at the large-scale assessment of the performance of available fold-recognition servers. Six popular servers were investigated: PDB-Blast, FFAS, T98-lib, GenTHREADER, 3D-PSSM, and INBGU. The assessment was conducted using as prediction targets a large number of selected protein structures released from October 1999 to April 2000. A target was selected if its sequence showed no significant similarity to any of the proteins previously available in the structural database. Overall, the servers were able to produce structurally similar models for one-half of the targets, but significantly accurate sequence-structure alignments were produced for only one-third of the targets. We further classified the targets into two sets: easy and hard. We found that all servers were able to find the correct answer for the vast majority of the easy targets if a structurally similar fold was present in the server's fold libraries. However, among the hard targets--where standard methods such as PSI-BLAST fail--the most sensitive fold-recognition servers were able to produce similar models for only 40% of the cases, half of which had a significantly accurate sequence-structure alignment. Among the hard targets, the presence of updated libraries appeared to be less critical for the ranking. An "ideally combined consensus" prediction, where the results of all servers are considered, would increase the percentage of correct assignments by 50%. Each server had a number of cases with a correct assignment, where the assignments of all the other servers were wrong. This emphasizes the benefits of considering more than one server in difficult prediction tasks. The LiveBench program (http://BioInfo.PL/LiveBench) is being continued, and all interested developers are cordially invited to join.

Getting started with SQL Server 2012 cube development

CERN Document Server

Lidberg, Simon

2013-01-01

As a practical tutorial for Analysis Services, get started with developing cubes. ""Getting Started with SQL Server 2012 Cube Development"" walks you through the basics, working with SSAS to build cubes and get them up and running.Written for SQL Server developers who have not previously worked with Analysis Services. It is assumed that you have experience with relational databases, but no prior knowledge of cube development is required. You need SQL Server 2012 in order to follow along with the exercises in this book.

CameraCast: flexible access to remote video sensors

Science.gov (United States)

Kong, Jiantao; Ganev, Ivan; Schwan, Karsten; Widener, Patrick

2007-01-01

New applications like remote surveillance and online environmental or traffic monitoring are making it increasingly important to provide flexible and protected access to remote video sensor devices. Current systems use application-level codes like web-based solutions to provide such access. This requires adherence to user-level APIs provided by such services, access to remote video information through given application-specific service and server topologies, and that the data being captured and distributed is manipulated by third party service codes. CameraCast is a simple, easily used system-level solution to remote video access. It provides a logical device API so that an application can identically operate on local vs. remote video sensor devices, using its own service and server topologies. In addition, the application can take advantage of API enhancements to protect remote video information, using a capability-based model for differential data protection that offers fine grain control over the information made available to specific codes or machines, thereby limiting their ability to violate privacy or security constraints. Experimental evaluations of CameraCast show that the performance of accessing remote video information approximates that of accesses to local devices, given sufficient networking resources. High performance is also attained when protection restrictions are enforced, due to an efficient kernel-level realization of differential data protection.

An Electronic Healthcare Record Server Implemented in PostgreSQL

Directory of Open Access Journals (Sweden)

Tony Austin

2015-01-01

Full Text Available This paper describes the implementation of an Electronic Healthcare Record server inside a PostgreSQL relational database without dependency on any further middleware infrastructure. The five-part international standard for communicating healthcare records (ISO EN 13606 is used as the information basis for the design of the server. We describe some of the features that this standard demands that are provided by the server, and other areas where assumptions about the durability of communications or the presence of middleware lead to a poor fit. Finally, we discuss the use of the server in two real-world scenarios including a commercial application.

Client Server design and implementation issues in the Accelerator Control System environment

International Nuclear Information System (INIS)

Sathe, S.; Hoff, L.; Clifford, T.

1995-01-01

In distributed system communication software design, the Client Server model has been widely used. This paper addresses the design and implementation issues of such a model, particularly when used in Accelerator Control Systems. in designing the Client Server model one needs to decide how the services will be defined for a server, what types of messages the server will respond to, which data formats will be used for the network transactions and how the server will be located by the client. Special consideration needs to be given to error handling both on the server and client side. Since the server usually is located on a machine other than the client, easy and informative server diagnostic capability is required. The higher level abstraction provided by the Client Server model simplifies the application writing, however fine control over network parameters is essential to improve the performance. Above mentioned design issues and implementation trade-offs are discussed in this paper

On a Batch Arrival Queuing System Equipped with a Stand-by Server during Vacation Periods or the Repairs Times of the Main Server

Directory of Open Access Journals (Sweden)

Rehab F. Khalaf

2011-01-01

Full Text Available We study a queuing system which is equipped with a stand-by server in addition to the main server. The stand-by server provides service to customers only during the period of absence of the main server when either the main server is on a vacation or it is in the state of repairs due to a sudden failure from time to time. The service times, vacation times, and repair times are assumed to follow general arbitrary distributions while the stand-by service times follow exponential distribution. Supplementary variables technique has been used to obtain steady state results in explicit and closed form in terms of the probability generating functions for the number of customers in the queue, the average number of customers, and the average waiting time in the queue while the MathCad software has been used to illustrate the numerical results in this work.

Comparison of Certification Authority Roles in Windows Server 2003 and Windows Server 2008

Directory of Open Access Journals (Sweden)

A. I. Luchnik

2011-03-01

Full Text Available An analysis of Certification Authority components of Microsoft server operating systems was conducted. Based on the results main directions of development of certification authorities and PKI were highlighted.

Towards Direct Manipulation and Remixing of Massive Data: The EarthServer Approach

Science.gov (United States)

Baumann, P.

2012-04-01

Complex analytics on "big data" is one of the core challenges of current Earth science, generating strong requirements for on-demand processing and fil tering of massive data sets. Issues under discussion include flexibility, performance, scalability, and the heterogeneity of the information types invo lved. In other domains, high-level query languages (such as those offered by database systems) have proven successful in the quest for flexible, scalable data access interfaces to massive amounts of data. However, due to the lack of support for many of the Earth science data structures, database systems are only used for registries and catalogs, but not for the bulk of spatio-temporal data. One core information category in this field is given by coverage data. ISO 19123 defines coverages, simplifying, as a representation of a "space-time varying phenomenon". This model can express a large class of Earth science data structures, including rectified and non-rectified rasters, curvilinear grids, point clouds, TINs, general meshes, trajectories, surfaces, and solids. This abstract definition, which is too high-level to establish interoperability, is concretized by the OGC GML 3.2.1 Application Schema for Coverages Standard into an interoperable representation. The OGC Web Coverage Processing Service (WCPS) Standard defines a declarative query language on multi-dimensional raster-type coverages, such as 1D in-situ sensor timeseries, 2D EO imagery, 3D x/y/t image time series and x/y/z geophysical data, 4D x/y/z/t climate and ocean data. Hence, important ingredients for versatile coverage retrieval are given - however, this potential has not been fully unleashed by service architectures up to now. The EU FP7-INFRA project EarthServer, launched in September 2011, aims at enabling standards-based on-demand analytics over the Web for Earth science data based on an integration of W3C XQuery for alphanumeric data and OGC-WCPS for raster data. Ultimately, EarthServer will support

The SMARTCyp cytochrome P450 metabolism prediction server

DEFF Research Database (Denmark)

Rydberg, Patrik; Gloriam, David Erik Immanuel; Olsen, Lars

2010-01-01

The SMARTCyp server is the first web application for site of metabolism prediction of cytochrome P450-mediated drug metabolism.......The SMARTCyp server is the first web application for site of metabolism prediction of cytochrome P450-mediated drug metabolism....

MotifNet: a web-server for network motif analysis.

Science.gov (United States)

Smoly, Ilan Y; Lerman, Eugene; Ziv-Ukelson, Michal; Yeger-Lotem, Esti

2017-06-15

Network motifs are small topological patterns that recur in a network significantly more often than expected by chance. Their identification emerged as a powerful approach for uncovering the design principles underlying complex networks. However, available tools for network motif analysis typically require download and execution of computationally intensive software on a local computer. We present MotifNet, the first open-access web-server for network motif analysis. MotifNet allows researchers to analyze integrated networks, where nodes and edges may be labeled, and to search for motifs of up to eight nodes. The output motifs are presented graphically and the user can interactively filter them by their significance, number of instances, node and edge labels, and node identities, and view their instances. MotifNet also allows the user to distinguish between motifs that are centered on specific nodes and motifs that recur in distinct parts of the network. MotifNet is freely available at http://netbio.bgu.ac.il/motifnet . The website was implemented using ReactJs and supports all major browsers. The server interface was implemented in Python with data stored on a MySQL database. estiyl@bgu.ac.il or michaluz@cs.bgu.ac.il. Supplementary data are available at Bioinformatics online. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

Condensing Massive Satellite Datasets For Rapid Interactive Analysis

Science.gov (United States)

Grant, G.; Gallaher, D. W.; Lv, Q.; Campbell, G. G.; Fowler, C.; LIU, Q.; Chen, C.; Klucik, R.; McAllister, R. A.

2015-12-01

Our goal is to enable users to interactively analyze massive satellite datasets, identifying anomalous data or values that fall outside of thresholds. To achieve this, the project seeks to create a derived database containing only the most relevant information, accelerating the analysis process. The database is designed to be an ancillary tool for the researcher, not an archival database to replace the original data. This approach is aimed at improving performance by reducing the overall size by way of condensing the data. The primary challenges of the project include: - The nature of the research question(s) may not be known ahead of time. - The thresholds for determining anomalies may be uncertain. - Problems associated with processing cloudy, missing, or noisy satellite imagery. - The contents and method of creation of the condensed dataset must be easily explainable to users. The architecture of the database will reorganize spatially-oriented satellite imagery into temporally-oriented columns of data (a.k.a., "data rods") to facilitate time-series analysis. The database itself is an open-source parallel database, designed to make full use of clustered server technologies. A demonstration of the system capabilities will be shown. Applications for this technology include quick-look views of the data, as well as the potential for on-board satellite processing of essential information, with the goal of reducing data latency.

OceanNOMADS: Real-time and retrospective access to operational U.S. ocean prediction products

Science.gov (United States)

Harding, J. M.; Cross, S. L.; Bub, F.; Ji, M.

2011-12-01

The National Oceanic and Atmospheric Administration (NOAA) National Operational Model Archive and Distribution System (NOMADS) provides both real-time and archived atmospheric model output from servers at the National Centers for Environmental Prediction (NCEP) and National Climatic Data Center (NCDC) respectively (http://nomads.ncep.noaa.gov/txt_descriptions/marRutledge-1.pdf). The NOAA National Ocean Data Center (NODC) with NCEP is developing a complementary capability called OceanNOMADS for operational ocean prediction models. An NCEP ftp server currently provides real-time ocean forecast output (http://www.opc.ncep.noaa.gov/newNCOM/NCOM_currents.shtml) with retrospective access through NODC. A joint effort between the Northern Gulf Institute (NGI; a NOAA Cooperative Institute) and the NOAA National Coastal Data Development Center (NCDDC; a division of NODC) created the developmental version of the retrospective OceanNOMADS capability (http://www.northerngulfinstitute.org/edac/ocean_nomads.php) under the NGI Ecosystem Data Assembly Center (EDAC) project (http://www.northerngulfinstitute.org/edac/). Complementary funding support for the developmental OceanNOMADS from U.S. Integrated Ocean Observing System (IOOS) through the Southeastern University Research Association (SURA) Model Testbed (http://testbed.sura.org/) this past year provided NODC the analogue that facilitated the creation of an NCDDC production version of OceanNOMADS (http://www.ncddc.noaa.gov/ocean-nomads/). Access tool development and storage of initial archival data sets occur on the NGI/NCDDC developmental servers with transition to NODC/NCCDC production servers as the model archives mature and operational space and distribution capability grow. Navy operational global ocean forecast subsets for U.S waters comprise the initial ocean prediction fields resident on the NCDDC production server. The NGI/NCDDC developmental server currently includes the Naval Research Laboratory Inter-America Seas

CACHING DATA STORED IN SQL SERVER FOR OPTIMIZING THE PERFORMANCE

Directory of Open Access Journals (Sweden)

Demian Horia

2016-12-01

Full Text Available This paper present the architecture of web site with different techniques used for optimize the performance of loading the web content. The architecture presented here is for e-commerce site developed on windows with MVC, IIS and Micosoft SQL Server. Caching the data is one technique used by the browsers, by the web servers itself or by proxy servers. Caching the data is made without the knowledge of users and need to provide to user the more recent information from the server. This means that caching mechanism has to be aware of any modification of data on the server. There are different information’s presented in e-commerce site related to products like images, code of product, description, properties or stock

PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality

Directory of Open Access Journals (Sweden)

Rooman Marianne

2011-05-01

Full Text Available Abstract Background The rational design of modified proteins with controlled stability is of extreme importance in a whole range of applications, notably in the biotechnological and environmental areas, where proteins are used for their catalytic or other functional activities. Future breakthroughs in medical research may also be expected from an improved understanding of the effect of naturally occurring disease-causing mutations on the molecular level. Results PoPMuSiC-2.1 is a web server that predicts the thermodynamic stability changes caused by single site mutations in proteins, using a linear combination of statistical potentials whose coefficients depend on the solvent accessibility of the mutated residue. PoPMuSiC presents good prediction performances (correlation coefficient of 0.8 between predicted and measured stability changes, in cross validation, after exclusion of 10% outliers. It is moreover very fast, allowing the prediction of the stability changes resulting from all possible mutations in a medium size protein in less than a minute. This unique functionality is user-friendly implemented in PoPMuSiC and is particularly easy to exploit. Another new functionality of our server concerns the estimation of the optimality of each amino acid in the sequence, with respect to the stability of the structure. It may be used to detect structural weaknesses, i.e. clusters of non-optimal residues, which represent particularly interesting sites for introducing targeted mutations. This sequence optimality data is also expected to have significant implications in the prediction and the analysis of particular structural or functional protein regions. To illustrate the interest of this new functionality, we apply it to a dataset of known catalytic sites, and show that a much larger than average concentration of structural weaknesses is detected, quantifying how these sites have been optimized for function rather than stability. Conclusion The

Asynchronous data change notification between database server and accelerator control systems

International Nuclear Information System (INIS)

Wenge Fu; Seth Nemesure; Morris, J.

2012-01-01

Database data change notification (DCN) is a commonly used feature, it allows to be informed when the data has been changed on the server side by another client. Not all database management systems (DBMS) provide an explicit DCN mechanism. Even for those DBMS's which support DCN (such as Oracle and MS SQL server), some server side and/or client side programming may be required to make the DCN system work. This makes the setup of DCN between database server and interested clients tedious and time consuming. In accelerator control systems, there are many well established software client/server architectures (such as CDEV, EPICS, and ADO) that can be used to implement data reflection servers that transfer data asynchronously to any client using the standard SET/GET API. This paper describes a method for using such a data reflection server to set up asynchronous DCN (ADCN) between a DBMS and clients. This method works well for all DBMS systems which provide database trigger functionality. (authors)

Two Stage Secure Dynamic Load Balancing Architecture for SIP Server Clusters

Directory of Open Access Journals (Sweden)

G. Vennila

2014-08-01

Full Text Available Session Initiation Protocol (SIP is a signaling protocol emerged with an aim to enhance the IP network capabilities in terms of complex service provision. SIP server scalability with load balancing has a greater concern due to the dramatic increase in SIP service demand. Load balancing of session method (request/response and security measures optimizes the SIP server to regulate of network traffic in Voice over Internet Protocol (VoIP. Establishing a honeywall prior to the load balancer significantly reduces SIP traffic and drops inbound malicious load. In this paper, we propose Active Least Call in SIP Server (ALC_Server algorithm fulfills objectives like congestion avoidance, improved response times, throughput, resource utilization, reducing server faults, scalability and protection of SIP call from DoS attacks. From the test bed, the proposed two-tier architecture demonstrates that the ALC_Server method dynamically controls the overload and provides robust security, uniform load distribution for SIP servers.

Large scale access tests and online interfaces to ATLAS conditions databases

International Nuclear Information System (INIS)

Amorim, A; Lopes, L; Pereira, P; Simoes, J; Soloviev, I; Burckhart, D; Schmitt, J V D; Caprini, M; Kolos, S

2008-01-01

The access of the ATLAS Trigger and Data Acquisition (TDAQ) system to the ATLAS Conditions Databases sets strong reliability and performance requirements on the database storage and access infrastructures. Several applications were developed to support the integration of Conditions database access with the online services in TDAQ, including the interface to the Information Services (IS) and to the TDAQ Configuration Databases. The information storage requirements were the motivation for the ONline A Synchronous Interface to COOL (ONASIC) from the Information Service (IS) to LCG/COOL databases. ONASIC avoids the possible backpressure from Online Database servers by managing a local cache. In parallel, OKS2COOL was developed to store Configuration Databases into an Offline Database with history record. The DBStressor application was developed to test and stress the access to the Conditions database using the LCG/COOL interface while operating in an integrated way as a TDAQ application. The performance scaling of simultaneous Conditions database read accesses was studied in the context of the ATLAS High Level Trigger large computing farms. A large set of tests were performed involving up to 1000 computing nodes that simultaneously accessed the LCG central database server infrastructure at CERN

Design and Analysis of an Enhanced Patient-Server Mutual Authentication Protocol for Telecare Medical Information System.

Science.gov (United States)

Amin, Ruhul; Islam, S K Hafizul; Biswas, G P; Khan, Muhammad Khurram; Obaidat, Mohammad S

2015-11-01

In order to access remote medical server, generally the patients utilize smart card to login to the server. It has been observed that most of the user (patient) authentication protocols suffer from smart card stolen attack that means the attacker can mount several common attacks after extracting smart card information. Recently, Lu et al.'s proposes a session key agreement protocol between the patient and remote medical server and claims that the same protocol is secure against relevant security attacks. However, this paper presents several security attacks on Lu et al.'s protocol such as identity trace attack, new smart card issue attack, patient impersonation attack and medical server impersonation attack. In order to fix the mentioned security pitfalls including smart card stolen attack, this paper proposes an efficient remote mutual authentication protocol using smart card. We have then simulated the proposed protocol using widely-accepted AVISPA simulation tool whose results make certain that the same protocol is secure against active and passive attacks including replay and man-in-the-middle attacks. Moreover, the rigorous security analysis proves that the proposed protocol provides strong security protection on the relevant security attacks including smart card stolen attack. We compare the proposed scheme with several related schemes in terms of computation cost and communication cost as well as security functionalities. It has been observed that the proposed scheme is comparatively better than related existing schemes.

SVM-Prot 2016: A Web-Server for Machine Learning Prediction of Protein Functional Families from Sequence Irrespective of Similarity.

Science.gov (United States)

Li, Ying Hong; Xu, Jing Yu; Tao, Lin; Li, Xiao Feng; Li, Shuang; Zeng, Xian; Chen, Shang Ying; Zhang, Peng; Qin, Chu; Zhang, Cheng; Chen, Zhe; Zhu, Feng; Chen, Yu Zong

2016-01-01

Knowledge of protein function is important for biological, medical and therapeutic studies, but many proteins are still unknown in function. There is a need for more improved functional prediction methods. Our SVM-Prot web-server employed a machine learning method for predicting protein functional families from protein sequences irrespective of similarity, which complemented those similarity-based and other methods in predicting diverse classes of proteins including the distantly-related proteins and homologous proteins of different functions. Since its publication in 2003, we made major improvements to SVM-Prot with (1) expanded coverage from 54 to 192 functional families, (2) more diverse protein descriptors protein representation, (3) improved predictive performances due to the use of more enriched training datasets and more variety of protein descriptors, (4) newly integrated BLAST analysis option for assessing proteins in the SVM-Prot predicted functional families that were similar in sequence to a query protein, and (5) newly added batch submission option for supporting the classification of multiple proteins. Moreover, 2 more machine learning approaches, K nearest neighbor and probabilistic neural networks, were added for facilitating collective assessment of protein functions by multiple methods. SVM-Prot can be accessed at http://bidd2.nus.edu.sg/cgi-bin/svmprot/svmprot.cgi.

Optimal control of M/M/1 two-phase queueing system with state-dependent arrival rate, server breakdowns, delayed repair, and N-policy

Science.gov (United States)

Rao, Hanumantha; Kumar, Vasanta; Srinivasa Rao, T.; Srinivasa Kumar, B.

2018-04-01

In this paper, we examine a two-stage queueing system where the arrivals are Poisson with rate depends on the condition of the server to be specific: vacation, pre-service, operational or breakdown state. The service station is liable to breakdowns and deferral in repair because of non-accessibility of the repair facility. The service is in two basic stages, the first being bulk service to every one of the customers holding up on the line and the second stage is individual to each of them. The server works under N-policy. The server needs preliminary time (startup time) to begin batch service after a vacation period. Startup times, uninterrupted service times, the length of each vacation period, delay times and service times follows an exponential distribution. The closed form of expressions for the mean system size at different conditions of the server is determined. Numerical investigations are directed to concentrate the impact of the system parameters on the ideal limit N and the minimum base expected unit cost.

Asynchronous data change notification between database server and accelerator controls system

International Nuclear Information System (INIS)

Fu, W.; Morris, J.; Nemesure, S.

2011-01-01

Database data change notification (DCN) is a commonly used feature. Not all database management systems (DBMS) provide an explicit DCN mechanism. Even for those DBMS's which support DCN (such as Oracle and MS SQL server), some server side and/or client side programming may be required to make the DCN system work. This makes the setup of DCN between database server and interested clients tedious and time consuming. In accelerator control systems, there are many well established software client/server architectures (such as CDEV, EPICS, and ADO) that can be used to implement data reflection servers that transfer data asynchronously to any client using the standard SET/GET API. This paper describes a method for using such a data reflection server to set up asynchronous DCN (ADCN) between a DBMS and clients. This method works well for all DBMS systems which provide database trigger functionality. Asynchronous data change notification (ADCN) between database server and clients can be realized by combining the use of a database trigger mechanism, which is supported by major DBMS systems, with server processes that use client/server software architectures that are familiar in the accelerator controls community (such as EPICS, CDEV or ADO). This approach makes the ADCN system easy to set up and integrate into an accelerator controls system. Several ADCN systems have been set up and used in the RHIC-AGS controls system.

Analisis Algoritma Pergantian Cache Pada Proxy Web Server Internet Dengan Simulasi

OpenAIRE

Nurwarsito, Heru

2007-01-01

Pertumbuhan jumlah client internet dari waktu ke waktu terus bertambah, maka respon akses internet menjadi semakin lambat. Untuk membantu kecepatan akses tersebut maka diperlukan cache pada Proxy Server. Penelitian ini bertujuan untuk menganalisis performansi Proxy Server pada Jaringan Internet terhadap penggunaan algoritma pergantian cache-nya.Analisis Algoritma Pergantian Cache Pada Proxy Server didesain dengan metoda pemodelan simulasi jaringan internet yang terdiri dari Web server, Proxy ...

Solution for an Improved WEB Server

Directory of Open Access Journals (Sweden)

George PECHERLE

2009-12-01

Full Text Available We want to present a solution with maximum performance from a web server,in terms of services that the server provides. We do not always know what tools to useor how to configure what we have in order to get what we need. Keeping the Internetrelatedservices you provide in working condition can sometimes be a real challenge.And with the increasing demand in Internet services, we need to come up with solutionsto problems that occur every day.

On the single-server retrial queue

Directory of Open Access Journals (Sweden)

Djellab Natalia V.

2006-01-01

Full Text Available In this work, we review the stochastic decomposition for the number of customers in M/G/1 retrial queues with reliable server and server subjected to breakdowns which has been the subject of investigation in the literature. Using the decomposition property of M/G/1 retrial queues with breakdowns that holds under exponential assumption for retrial times as an approximation in the non-exponential case, we consider an approximate solution for the steady-state queue size distribution.

Server Interface Descriptions for Automated Testing of JavaScript Web Applications

DEFF Research Database (Denmark)

Jensen, Casper Svenning; Møller, Anders; Su, Zhendong

2013-01-01

Automated testing of JavaScript web applications is complicated by the communication with servers. Specifically, it is difficult to test the JavaScript code in isolation from the server code and database contents. We present a practical solution to this problem. First, we demonstrate that formal...... server interface descriptions are useful in automated testing of JavaScript web applications for separating the concerns of the client and the server. Second, to support the construction of server interface descriptions for existing applications, we introduce an effective inference technique that learns...... communication patterns from sample data. By incorporating interface descriptions into the testing tool Artemis, our experimental results show that we increase the level of automation for high-coverage testing on a collection of JavaScript web applications that exchange JSON data between the clients and servers...

Medical Image Data and Datasets in the Era of Machine Learning-Whitepaper from the 2016 C-MIMI Meeting Dataset Session.

Science.gov (United States)

Kohli, Marc D; Summers, Ronald M; Geis, J Raymond

2017-08-01

At the first annual Conference on Machine Intelligence in Medical Imaging (C-MIMI), held in September 2016, a conference session on medical image data and datasets for machine learning identified multiple issues. The common theme from attendees was that everyone participating in medical image evaluation with machine learning is data starved. There is an urgent need to find better ways to collect, annotate, and reuse medical imaging data. Unique domain issues with medical image datasets require further study, development, and dissemination of best practices and standards, and a coordinated effort among medical imaging domain experts, medical imaging informaticists, government and industry data scientists, and interested commercial, academic, and government entities. High-level attributes of reusable medical image datasets suitable to train, test, validate, verify, and regulate ML products should be better described. NIH and other government agencies should promote and, where applicable, enforce, access to medical image datasets. We should improve communication among medical imaging domain experts, medical imaging informaticists, academic clinical and basic science researchers, government and industry data scientists, and interested commercial entities.

TRAP: A Three-Way Handshake Server for TCP Connection Establishment

Directory of Open Access Journals (Sweden)

Fu-Hau Hsu

2016-11-01

Full Text Available Distributed denial of service attacks have become more and more frequent nowadays. In 2013, a massive distributed denial of service (DDoS attack was launched against Spamhaus causing the service to shut down. In this paper, we present a three-way handshaking server for Transmission Control Protocol (TCP connection redirection utilizing TCP header options. When a legitimate client attempted to connect to a server undergoing an SYN-flood DDoS attack, it will try to initiate a three-way handshake. After it has successfully established a connection, the server will reply with a reset (RST packet, in which a new server address and a secret is embedded. The client can, thus, connect to the new server that only accepts SYN packets with the corrected secret using the supplied secret.

Expert T-SQL window functions in SQL Server

CERN Document Server

Kellenberger, Kathi

2015-01-01

Expert T-SQL Window Functions in SQL Server takes you from any level of knowledge of windowing functions and turns you into an expert who can use these powerful functions to solve many T-SQL queries. Replace slow cursors and self-joins with queries that are easy to write and fantastically better performing, all through the magic of window functions. First introduced in SQL Server 2005, window functions came into full blossom with SQL Server 2012. They truly are one of the most notable developments in SQL in a decade, and every developer and DBA can benefit from their expressive power in sol

A Fuzzy Control Course on the TED Server

DEFF Research Database (Denmark)

Dotoli, Mariagrazia; Jantzen, Jan

1999-01-01

, an educational server that serves as a learning central for students and professionals working with fuzzy logic. Through the server, TED offers an online course on fuzzy control. The course concerns automatic control of an inverted pendulum, with a focus on rule based control by means of fuzzy logic. A ball......The Training and Education Committee (TED) is a committee under ERUDIT, a Network of Excellence for fuzzy technology and uncertainty in Europe. The main objective of TED is to improve the training and educational possibilities for the nodes of ERUDIT. Since early 1999, TED has set up the TED server...

Aplikasi Billing Client/Server Dengan Mengunakan Microsoft Visual Basic 6.0

OpenAIRE

Sinukaban, Eva Solida

2010-01-01

Kajian ini bertujuan untuk membangun Billing Server yang gratis dalam jaringan Local dengan media transmisi berupa kabel UTP atau Wifi, Jaringan LAN yang dibangun ini merupakan jaringan client server yang memiliki server dengan sistem operasi yang dipakai adalah windows XP Service Pack 2. Tujuan pembuatan Aplikasi Billing Server ini adalah untuk dapat melakukan sharing data dan komunikasi antar komputer sehingga komputer-komputer tersebut dapat dimanfaatkan seoptimal mungkin baik dari sisi Se...

EPICS channel access using websocket

International Nuclear Information System (INIS)

Uchiyama, A.; Furukawa, K.; Higurashi, Y.

2012-01-01

Web technology is useful as a means of widely disseminating accelerator and beam status information. For this purpose, WebOPI was implemented by SNS as a web-based system using Ajax (asynchronous JavaScript and XML) with EPICS. On the other hand, it is often necessary to control the accelerator from different locations as well as the central control room during beam operation and maintenance. However, it is not realistic to replace the GUI-based operator interface (OPI) with a Web-based system using Ajax technology because of interactive performance issue. Therefore, as a next generation OPI over the web using EPICS Channel Access (CA), we developed a client system based on WebSocket, which is a new protocol provided by the Internet Engineering Task Force (IETF) for Web-based systems. WebSocket is a web technology that provides bidirectional, full-duplex communication channels over a single TCP connection. By utilizing Node.js and the WebSocket access library called Socket.IO, a WebSocket server was implemented. Node.js is a server-side JavaScript language built on the Google V8 JavaScript Engine. In order to construct the WebSocket server as an EPICS CA client, an add-on for Node.js was developed in C/C++ using the EPICS CA library, which is included in the EPICS base. As a result, for accelerator operation, Web-based client systems became available not only in the central control room but also with various types of equipment. (author)

Openlobby: an open game server for lobby and matchmaking

Science.gov (United States)

Zamzami, E. M.; Tarigan, J. T.; Jaya, I.; Hardi, S. M.

2018-03-01

Online Multiplayer is one of the most essential feature in modern games. However, while developing a multiplayer feature can be done with a simple computer networking programming, creating a balanced multiplayer session requires more player management components such as game lobby and matchmaking system. Our objective is to develop OpenLobby, a server that available to be used by other developers to support their multiplayer application. The proposed system acts as a lobby and matchmaker where queueing players will be matched to other player according to a certain criteria defined by developer. The solution provides an application programing interface that can be used by developer to interact with the server. For testing purpose, we developed a game that uses the server as their multiplayer server.

ProTox: a web server for the in silico prediction of rodent oral toxicity.

Science.gov (United States)

Drwal, Malgorzata N; Banerjee, Priyanka; Dunkel, Mathias; Wettig, Martin R; Preissner, Robert

2014-07-01

Animal trials are currently the major method for determining the possible toxic effects of drug candidates and cosmetics. In silico prediction methods represent an alternative approach and aim to rationalize the preclinical drug development, thus enabling the reduction of the associated time, costs and animal experiments. Here, we present ProTox, a web server for the prediction of rodent oral toxicity. The prediction method is based on the analysis of the similarity of compounds with known median lethal doses (LD50) and incorporates the identification of toxic fragments, therefore representing a novel approach in toxicity prediction. In addition, the web server includes an indication of possible toxicity targets which is based on an in-house collection of protein-ligand-based pharmacophore models ('toxicophores') for targets associated with adverse drug reactions. The ProTox web server is open to all users and can be accessed without registration at: http://tox.charite.de/tox. The only requirement for the prediction is the two-dimensional structure of the input compounds. All ProTox methods have been evaluated based on a diverse external validation set and displayed strong performance (sensitivity, specificity and precision of 76, 95 and 75%, respectively) and superiority over other toxicity prediction tools, indicating their possible applicability for other compound classes. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

Using Pattern Recognition Techniques for Server Overload Detection

NARCIS (Netherlands)

Bezemer, C.P.; Cheplygina, V.; Zaidman, A.

2011-01-01

One of the key factors in customer satisfaction is application performance. To be able to guarantee good performance, it is necessary to take appropriate measures before a server overload occurs. While in small systems it is usually possible to predict server overload using a subjective human

Server virtualization management of corporate network with hyper-v

OpenAIRE

Kovalenko, Taras

2012-01-01

On a paper main tasks and problems of server virtualization are considerate. Practical value of virtualization in a corporate network, advantages and disadvantages of application of server virtualization are also considerate.

Empirical Analysis of Server Consolidation and Desktop Virtualization in Cloud Computing

Directory of Open Access Journals (Sweden)

Bao Rong Chang

2013-01-01

Full Text Available Physical server transited to virtual server infrastructure (VSI and desktop device to virtual desktop infrastructure (VDI have the crucial problems of server consolidation, virtualization performance, virtual machine density, total cost of ownership (TCO, and return on investments (ROI. Besides, how to appropriately choose hypervisor for the desired server/desktop virtualization is really challenging, because a trade-off between virtualization performance and cost is a hard decision to make in the cloud. This paper introduces five hypervisors to establish the virtual environment and then gives a careful assessment based on C/P ratio that is derived from composite index, consolidation ratio, virtual machine density, TCO, and ROI. As a result, even though ESX server obtains the highest ROI and lowest TCO in server virtualization and Hyper-V R2 gains the best performance of virtual machine management; both of them however cost too much. Instead the best choice is Proxmox Virtual Environment (Proxmox VE because it not only saves the initial investment a lot to own a virtual server/desktop infrastructure, but also obtains the lowest C/P ratio.

GENESIS SciFlo: Choreographing Interoperable Web Services on the Grid using a Semantically-Enabled Dataflow Execution Environment

Science.gov (United States)

Wilson, B. D.; Manipon, G.; Xing, Z.

2007-12-01

The General Earth Science Investigation Suite (GENESIS) project is a NASA-sponsored partnership between the Jet Propulsion Laboratory, academia, and NASA data centers to develop a new suite of Web Services tools to facilitate multi-sensor investigations in Earth System Science. The goal of GENESIS is to enable large-scale, multi-instrument atmospheric science using combined datasets from the AIRS, MODIS, MISR, and GPS sensors. Investigations include cross-comparison of spaceborne climate sensors, cloud spectral analysis, study of upper troposphere-stratosphere water transport, study of the aerosol indirect cloud effect, and global climate model validation. The challenges are to bring together very large datasets, reformat and understand the individual instrument retrievals, co-register or re-grid the retrieved physical parameters, perform computationally-intensive data fusion and data mining operations, and accumulate complex statistics over months to years of data. To meet these challenges, we have developed a Grid computing and dataflow framework, named SciFlo, in which we are deploying a set of versatile and reusable operators for data access, subsetting, registration, mining, fusion, compression, and advanced statistical analysis. SciFlo leverages remote Web Services, called via Simple Object Access Protocol (SOAP) or REST (one-line) URLs, and the Grid Computing standards (WS-* & Globus Alliance toolkits), and enables scientists to do multi- instrument Earth Science by assembling reusable Web Services and native executables into a distributed computing flow (tree of operators). The SciFlo client & server engines optimize the execution of such distributed data flows and allow the user to transparently find and use datasets and operators without worrying about the actual location of the Grid resources. In particular, SciFlo exploits the wealth of datasets accessible by OpenGIS Consortium (OGC) Web Mapping Servers & Web Coverage Servers (WMS/WCS), and by Open Data

A Research Graph dataset for connecting research data repositories using RD-Switchboard.

Science.gov (United States)

Aryani, Amir; Poblet, Marta; Unsworth, Kathryn; Wang, Jingbo; Evans, Ben; Devaraju, Anusuriya; Hausstein, Brigitte; Klas, Claus-Peter; Zapilko, Benjamin; Kaplun, Samuele

2018-05-29

This paper describes the open access graph dataset that shows the connections between Dryad, CERN, ANDS and other international data repositories to publications and grants across multiple research data infrastructures. The graph dataset was created using the Research Graph data model and the Research Data Switchboard (RD-Switchboard), a collaborative project by the Research Data Alliance DDRI Working Group (DDRI WG) with the aim to discover and connect the related research datasets based on publication co-authorship or jointly funded grants. The graph dataset allows researchers to trace and follow the paths to understanding a body of work. By mapping the links between research datasets and related resources, the graph dataset improves both their discovery and visibility, while avoiding duplicate efforts in data creation. Ultimately, the linked datasets may spur novel ideas, facilitate reproducibility and re-use in new applications, stimulate combinatorial creativity, and foster collaborations across institutions.

Windows Server® 2008 Inside Out

CERN Document Server

Stanek, William R

2009-01-01

Learn how to conquer Windows Server 2008-from the inside out! Designed for system administrators, this definitive resource features hundreds of timesaving solutions, expert insights, troubleshooting tips, and workarounds for administering Windows Server 2008-all in concise, fast-answer format. You will learn how to perform upgrades and migrations, automate deployments, implement security features, manage software updates and patches, administer users and accounts, manage Active Directory® directory services, and more. With INSIDE OUT, you'll discover the best and fastest ways to perform core a

Two-Cloud-Servers-Assisted Secure Outsourcing Multiparty Computation

Science.gov (United States)

Wen, Qiaoyan; Zhang, Hua; Jin, Zhengping; Li, Wenmin

2014-01-01

We focus on how to securely outsource computation task to the cloud and propose a secure outsourcing multiparty computation protocol on lattice-based encrypted data in two-cloud-servers scenario. Our main idea is to transform the outsourced data respectively encrypted by different users' public keys to the ones that are encrypted by the same two private keys of the two assisted servers so that it is feasible to operate on the transformed ciphertexts to compute an encrypted result following the function to be computed. In order to keep the privacy of the result, the two servers cooperatively produce a custom-made result for each user that is authorized to get the result so that all authorized users can recover the desired result while other unauthorized ones including the two servers cannot. Compared with previous research, our protocol is completely noninteractive between any users, and both of the computation and the communication complexities of each user in our solution are independent of the computing function. PMID:24982949

Improving data retrieval rates using remote data servers

International Nuclear Information System (INIS)

D'Ottavio, T.; Frak, B.; Nemesure, S.; Morris, J.

2012-01-01

The power and scope of modern Control Systems has led to an increased amount of data being collected and stored, including data collected at high (kHz) frequencies. One consequence is that users now routinely make data requests that can cause giga-bytes of data to be read and displayed. Given that a user's patience can be measured in seconds, this can be quite a technical challenge. This paper explores one possible solution to this problem - the creation of remote data servers whose performance is optimized to handle context-sensitive data requests. Methods for increasing data delivery performance include the use of high speed network connections between the stored data and the data servers, smart caching of frequently used data, and the culling of data delivered as determined by the context of the data request. This paper describes decisions made when constructing these servers and compares data retrieval performance by clients that use or do not use an intermediate data server. (authors)

Two-cloud-servers-assisted secure outsourcing multiparty computation.

Science.gov (United States)

Sun, Yi; Wen, Qiaoyan; Zhang, Yudong; Zhang, Hua; Jin, Zhengping; Li, Wenmin

2014-01-01

We focus on how to securely outsource computation task to the cloud and propose a secure outsourcing multiparty computation protocol on lattice-based encrypted data in two-cloud-servers scenario. Our main idea is to transform the outsourced data respectively encrypted by different users' public keys to the ones that are encrypted by the same two private keys of the two assisted servers so that it is feasible to operate on the transformed ciphertexts to compute an encrypted result following the function to be computed. In order to keep the privacy of the result, the two servers cooperatively produce a custom-made result for each user that is authorized to get the result so that all authorized users can recover the desired result while other unauthorized ones including the two servers cannot. Compared with previous research, our protocol is completely noninteractive between any users, and both of the computation and the communication complexities of each user in our solution are independent of the computing function.

Getting started with Oracle WebLogic Server 12c developer's guide

CERN Document Server

Nunes, Fabio Mazanatti

2013-01-01

Getting Started with Oracle WebLogic Server 12c is a fast-paced and feature-packed book, designed to get you working with Java EE 6, JDK 7 and Oracle WebLogic Server 12c straight away, so start developing your own applications.Getting Started with Oracle WebLogic Server 12c: Developer's Guide is written for developers who are just getting started, or who have some experience, with Java EE who want to learn how to develop for and use Oracle WebLogic Server. Getting Started with Oracle WebLogic Server 12c: Developer's Guide also provides a great overview of the updated features of the 12c releas

An accessibility solution of cloud computing by solar energy

Directory of Open Access Journals (Sweden)

Zuzana Priščáková

2013-01-01

Full Text Available Cloud computing is a modern innovative technology of solution of a problem with data storage, data processing, company infrastructure building and so on. Many companies worry over the changes by the implementation of this solution because these changes could have a negative impact on the company, or, in the case of establishment of new companies, this worry results from an unfamiliar environment. Data accessibility, integrity and security belong among basic problems of cloud computing. The aim of this paper is to offer and scientifically confirm a proposal of an accessibility solution of cloud by implementing of solar energy as a primary source. Problems with accessibility rise from power failures when data may be stolen or lost. Since cloud is often started from a server, the server dependence on power is strong. Modern conditions offer us a new, more innovative solution regarding the ecological as well as an economical company solution. The Sun as a steady source of energy offers us a possibility to produce necessary energy by a solar technique – solar panels. The connection of a solar panel as a primary source of energy for a server would remove its power dependence as well as possible failures. The power dependence would stay as a secondary source. Such an ecological solution would influence the economical side of company because the energy consumption would be lower. Besides a proposal of an accessibility solution, this paper involves a physical and mathematical solution to a calculation of solar energy showered on the Earth, a calculation of the panel size by cosines method and a simulation of these calculations in MATLAB conditions.

Instant Microsoft SQL Server Analysis Services 2012 dimensions and cube

CERN Document Server

Acharya, Anurag

2013-01-01

Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. Written in a practical, friendly manner this book will take you through the journey from installing SQL Server to developing your first cubes.""Microsoft SQL Server Analysis Service 2012 Dimensions"" and Cube Starter is targeted at anyone who wants to get started with cube development in Microsoft SQL Server Analysis Services. Regardless of whether you are a SQL Server developer who knows nothing about cube development or SSAS or even OLAP, you

deepTools2: a next generation web server for deep-sequencing data analysis.

Science.gov (United States)

Ramírez, Fidel; Ryan, Devon P; Grüning, Björn; Bhardwaj, Vivek; Kilpert, Fabian; Richter, Andreas S; Heyne, Steffen; Dündar, Friederike; Manke, Thomas

2016-07-08

We present an update to our Galaxy-based web server for processing and visualizing deeply sequenced data. Its core tool set, deepTools, allows users to perform complete bioinformatic workflows ranging from quality controls and normalizations of aligned reads to integrative analyses, including clustering and visualization approaches. Since we first described our deepTools Galaxy server in 2014, we have implemented new solutions for many requests from the community and our users. Here, we introduce significant enhancements and new tools to further improve data visualization and interpretation. deepTools continue to be open to all users and freely available as a web service at deeptools.ie-freiburg.mpg.de The new deepTools2 suite can be easily deployed within any Galaxy framework via the toolshed repository, and we also provide source code for command line usage under Linux and Mac OS X. A public and documented API for access to deepTools functionality is also available. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Data Access System for Hydrology

Science.gov (United States)

Whitenack, T.; Zaslavsky, I.; Valentine, D.; Djokic, D.

2007-12-01

As part of the CUAHSI HIS (Consortium of Universities for the Advancement of Hydrologic Science, Inc., Hydrologic Information System), the CUAHSI HIS team has developed Data Access System for Hydrology or DASH. DASH is based on commercial off the shelf technology, which has been developed in conjunction with a commercial partner, ESRI. DASH is a web-based user interface, developed in ASP.NET developed using ESRI ArcGIS Server 9.2 that represents a mapping, querying and data retrieval interface over observation and GIS databases, and web services. This is the front end application for the CUAHSI Hydrologic Information System Server. The HIS Server is a software stack that organizes observation databases, geographic data layers, data importing and management tools, and online user interfaces such as the DASH application, into a flexible multi- tier application for serving both national-level and locally-maintained observation data. The user interface of the DASH web application allows online users to query observation networks by location and attributes, selecting stations in a user-specified area where a particular variable was measured during a given time interval. Once one or more stations and variables are selected, the user can retrieve and download the observation data for further off-line analysis. The DASH application is highly configurable. The mapping interface can be configured to display map services from multiple sources in multiple formats, including ArcGIS Server, ArcIMS, and WMS. The observation network data is configured in an XML file where you specify the network's web service location and its corresponding map layer. Upon initial deployment, two national level observation networks (USGS NWIS daily values and USGS NWIS Instantaneous values) are already pre-configured. There is also an optional login page which can be used to restrict access as well as providing a alternative to immediate downloads. For large request, users would be notified via

Client/server approach to image capturing

Science.gov (United States)

Tuijn, Chris; Stokes, Earle

1998-01-01

The diversity of the digital image capturing devices on the market today is quite astonishing and ranges from low-cost CCD scanners to digital cameras (for both action and stand-still scenes), mid-end CCD scanners for desktop publishing and pre- press applications and high-end CCD flatbed scanners and drum- scanners with photo multiplier technology. Each device and market segment has its own specific needs which explains the diversity of the associated scanner applications. What all those applications have in common is the need to communicate with a particular device to import the digital images; after the import, additional image processing might be needed as well as color management operations. Although the specific requirements for all of these applications might differ considerably, a number of image capturing and color management facilities as well as other services are needed which can be shared. In this paper, we propose a client/server architecture for scanning and image editing applications which can be used as a common component for all these applications. One of the principal components of the scan server is the input capturing module. The specification of the input jobs is based on a generic input device model. Through this model we make abstraction of the specific scanner parameters and define the scan job definitions by a number of absolute parameters. As a result, scan job definitions will be less dependent on a particular scanner and have a more universal meaning. In this context, we also elaborate on the interaction of the generic parameters and the color characterization (i.e., the ICC profile). Other topics that are covered are the scheduling and parallel processing capabilities of the server, the image processing facilities, the interaction with the ICC engine, the communication facilities (both in-memory and over the network) and the different client architectures (stand-alone applications, TWAIN servers, plug-ins, OLE or Apple-event driven

Dynamic Web Pages: Performance Impact on Web Servers.

Science.gov (United States)

Kothari, Bhupesh; Claypool, Mark

2001-01-01

Discussion of Web servers and requests for dynamic pages focuses on experimentally measuring and analyzing the performance of the three dynamic Web page generation technologies: CGI, FastCGI, and Servlets. Develops a multivariate linear regression model and predicts Web server performance under some typical dynamic requests. (Author/LRW)

Comparing Server Energy Use and Efficiency Using Small Sample Sizes

Energy Technology Data Exchange (ETDEWEB)

Coles, Henry C.; Qin, Yong; Price, Phillip N.

2014-11-01

This report documents a demonstration that compared the energy consumption and efficiency of a limited sample size of server-type IT equipment from different manufacturers by measuring power at the server power supply power cords. The results are specific to the equipment and methods used. However, it is hoped that those responsible for IT equipment selection can used the methods described to choose models that optimize energy use efficiency. The demonstration was conducted in a data center at Lawrence Berkeley National Laboratory in Berkeley, California. It was performed with five servers of similar mechanical and electronic specifications; three from Intel and one each from Dell and Supermicro. Server IT equipment is constructed using commodity components, server manufacturer-designed assemblies, and control systems. Server compute efficiency is constrained by the commodity component specifications and integration requirements. The design freedom, outside of the commodity component constraints, provides room for the manufacturer to offer a product with competitive efficiency that meets market needs at a compelling price. A goal of the demonstration was to compare and quantify the server efficiency for three different brands. The efficiency is defined as the average compute rate (computations per unit of time) divided by the average energy consumption rate. The research team used an industry standard benchmark software package to provide a repeatable software load to obtain the compute rate and provide a variety of power consumption levels. Energy use when the servers were in an idle state (not providing computing work) were also measured. At high server compute loads, all brands, using the same key components (processors and memory), had similar results; therefore, from these results, it could not be concluded that one brand is more efficient than the other brands. The test results show that the power consumption variability caused by the key components as a

Mac OS X Snow Leopard Server For Dummies

CERN Document Server

Rizzo, John

2009-01-01

Making Everything Easier!. Mac OS® X Snow Leopard Server for Dummies. Learn to::;. Set up and configure a Mac network with Snow Leopard Server;. Administer, secure, and troubleshoot the network;. Incorporate a Mac subnet into a Windows Active Directory® domain;. Take advantage of Unix® power and security. John Rizzo. Want to set up and administer a network even if you don't have an IT department? Read on!. Like everything Mac, Snow Leopard Server was designed to be easy to set up and use. Still, there are so many options and features that this book will save you heaps of time and effort. It wa

A robust dataset-agnostic heart disease classifier from Phonocardiogram.

Science.gov (United States)

Banerjee, Rohan; Dutta Choudhury, Anirban; Deshpande, Parijat; Bhattacharya, Sakyajit; Pal, Arpan; Mandana, K M

2017-07-01

Automatic classification of normal and abnormal heart sounds is a popular area of research. However, building a robust algorithm unaffected by signal quality and patient demography is a challenge. In this paper we have analysed a wide list of Phonocardiogram (PCG) features in time and frequency domain along with morphological and statistical features to construct a robust and discriminative feature set for dataset-agnostic classification of normal and cardiac patients. The large and open access database, made available in Physionet 2016 challenge was used for feature selection, internal validation and creation of training models. A second dataset of 41 PCG segments, collected using our in-house smart phone based digital stethoscope from an Indian hospital was used for performance evaluation. Our proposed methodology yielded sensitivity and specificity scores of 0.76 and 0.75 respectively on the test dataset in classifying cardiovascular diseases. The methodology also outperformed three popular prior art approaches, when applied on the same dataset.

Accessing HEP Collaboration documents using WWW and WAIS

International Nuclear Information System (INIS)

Nguyen, T.D.; Buckley-Geer, E.; Ritchie, D.J.

1995-09-01

WAIS stands for Wide Area Information Server. It is a distributed information retrieval system. A WAIS system has a client-server architecture which consists of clients talking to a server via a TCP/IP network using the ANSI standard Z39-50 VI protocol. A freely available version (FreeWAIS) is supported by the Clearinghouse for Networked Information Discovery and Retrieval, also known as CNIDR. FreeWAIS-sf, which is the software the authors are using at Fermilab, is an extension of FreeWAIS. FreeWAIS-sf supports all the functionalities which FreeWAIS offers as well as additional indexing and searching capabilities for structured fields. World Wide Web (WWW) was originally developed by Tim Berners-Lee at CERN and is now the backbone for serving information on Internet. Here, the authors describe a system for accessing HEP collaboration documents using WWW and WAIS

Accessing HEP Collaboration documents using WWW and WAIS

Energy Technology Data Exchange (ETDEWEB)

Nguyen, T.D.; Buckley-Geer, E.; Ritchie, D.J.

1995-09-01

WAIS stands for Wide Area Information Server. It is a distributed information retrieval system. A WAIS system has a client-server architecture which consists of clients talking to a server via a TCP/IP network using the ANSI standard Z39-50 VI protocol. A freely available version (FreeWAIS) is supported by the Clearinghouse for Networked Information Discovery and Retrieval, also known as CNIDR. FreeWAIS-sf, which is the software the authors are using at Fermilab, is an extension of FreeWAIS. FreeWAIS-sf supports all the functionalities which FreeWAIS offers as well as additional indexing and searching capabilities for structured fields. World Wide Web (WWW) was originally developed by Tim Berners-Lee at CERN and is now the backbone for serving information on Internet. Here, the authors describe a system for accessing HEP collaboration documents using WWW and WAIS.

From Server to Desktop: Capital and Institutional Planning for Client/Server Technology.

Science.gov (United States)

Mullig, Richard M.; Frey, Keith W.

1994-01-01

Beginning with a request for an enhanced system for decision/strategic planning support, the University of Chicago's biological sciences division has developed a range of administrative client/server tools, instituted a capital replacement plan for desktop technology, and created a planning and staffing approach enabling rapid introduction of new…

iPhone with Microsoft Exchange Server 2010 Business Integration and Deployment

CERN Document Server

Goodman, Steve

2012-01-01

iPhone with Microsoft Exchange Server 2010 - Business Integration and Deployment is a practical, step-by-step tutorial on planning, installing and configuring Exchange Server to deploy iPhones into your business. This book is aimed at system administrators who don't necessarily know about Exchange Server 2010 or ActiveSync-based mobile devices. A basic level of knowledge around Windows Servers is expected, and knowledge of smartphones and email systems in general will make some topics a little easier.

WeBIAS: a web server for publishing bioinformatics applications.

Science.gov (United States)

Daniluk, Paweł; Wilczyński, Bartek; Lesyng, Bogdan

2015-11-02

One of the requirements for a successful scientific tool is its availability. Developing a functional web service, however, is usually considered a mundane and ungratifying task, and quite often neglected. When publishing bioinformatic applications, such attitude puts additional burden on the reviewers who have to cope with poorly designed interfaces in order to assess quality of presented methods, as well as impairs actual usefulness to the scientific community at large. In this note we present WeBIAS-a simple, self-contained solution to make command-line programs accessible through web forms. It comprises a web portal capable of serving several applications and backend schedulers which carry out computations. The server handles user registration and authentication, stores queries and results, and provides a convenient administrator interface. WeBIAS is implemented in Python and available under GNU Affero General Public License. It has been developed and tested on GNU/Linux compatible platforms covering a vast majority of operational WWW servers. Since it is written in pure Python, it should be easy to deploy also on all other platforms supporting Python (e.g. Windows, Mac OS X). Documentation and source code, as well as a demonstration site are available at http://bioinfo.imdik.pan.pl/webias . WeBIAS has been designed specifically with ease of installation and deployment of services in mind. Setting up a simple application requires minimal effort, yet it is possible to create visually appealing, feature-rich interfaces for query submission and presentation of results.

AsteriX: a Web server to automatically extract ligand coordinates from figures in PDF articles.

Science.gov (United States)

Lounnas, V; Vriend, G

2012-02-27

Coordinates describing the chemical structures of small molecules that are potential ligands for pharmaceutical targets are used at many stages of the drug design process. The coordinates of the vast majority of ligands can be obtained from either publicly accessible or commercial databases. However, interesting ligands sometimes are only available from the scientific literature, in which case their coordinates need to be reconstructed manually--a process that consists of a series of time-consuming steps. We present a Web server that helps reconstruct the three-dimensional (3D) coordinates of ligands for which a two-dimensional (2D) picture is available in a PDF file. The software, called AsteriX, analyses every picture contained in the PDF file and attempts to determine automatically whether or not it contains ligands. Areas in pictures that may contain molecular structures are processed to extract connectivity and atom type information that allow coordinates to be subsequently reconstructed. The AsteriX Web server was tested on a series of articles containing a large diversity in graphical representations. In total, 88% of 3249 ligand structures present in the test set were identified as chemical diagrams. Of these, about half were interpreted correctly as 3D structures, and a further one-third required only minor manual corrections. It is principally impossible to always correctly reconstruct 3D coordinates from pictures because there are many different protocols for drawing a 2D image of a ligand, but more importantly a wide variety of semantic annotations are possible. The AsteriX Web server therefore includes facilities that allow the users to augment partial or partially correct 3D reconstructions. All 3D reconstructions are submitted, checked, and corrected by the users domain at the server and are freely available for everybody. The coordinates of the reconstructed ligands are made available in a series of formats commonly used in drug design research. The

Microsoft SQL Server OLAP Solution - A Survey

OpenAIRE

Badiozamany, Sobhan

2010-01-01

Microsoft SQL Server 2008 offers technologies for performing On-Line Analytical Processing (OLAP), directly on data stored in data warehouses, instead of moving the data into some offline OLAP tool. This brings certain benefits, such as elimination of data copying and better integration with the DBMS compared with off-line OLAP tools. This report reviews SQL Server support for OLAP, solution architectures, tools and components involved. Standard storage options are discussed but the focus of ...

Development of a Personal Digital Assistant (PDA) based client/server NICU patient data and charting system.

Science.gov (United States)

Carroll, A E; Saluja, S; Tarczy-Hornoch, P

2001-01-01

Personal Digital Assistants (PDAs) offer clinicians the ability to enter and manage critical information at the point of care. Although PDAs have always been designed to be intuitive and easy to use, recent advances in technology have made them even more accessible. The ability to link data on a PDA (client) to a central database (server) allows for near-unlimited potential in developing point of care applications and systems for patient data management. Although many stand-alone systems exist for PDAs, none are designed to work in an integrated client/server environment. This paper describes the design, software and hardware selection, and preliminary testing of a PDA based patient data and charting system for use in the University of Washington Neonatal Intensive Care Unit (NICU). This system will be the subject of a subsequent study to determine its impact on patient outcomes and clinician efficiency.

Two-Cloud-Servers-Assisted Secure Outsourcing Multiparty Computation

Directory of Open Access Journals (Sweden)

Yi Sun

2014-01-01

Full Text Available We focus on how to securely outsource computation task to the cloud and propose a secure outsourcing multiparty computation protocol on lattice-based encrypted data in two-cloud-servers scenario. Our main idea is to transform the outsourced data respectively encrypted by different users’ public keys to the ones that are encrypted by the same two private keys of the two assisted servers so that it is feasible to operate on the transformed ciphertexts to compute an encrypted result following the function to be computed. In order to keep the privacy of the result, the two servers cooperatively produce a custom-made result for each user that is authorized to get the result so that all authorized users can recover the desired result while other unauthorized ones including the two servers cannot. Compared with previous research, our protocol is completely noninteractive between any users, and both of the computation and the communication complexities of each user in our solution are independent of the computing function.

The new Planetary Science Archive: A tool for exploration and discovery of scientific datasets from ESA's planetary missions

Science.gov (United States)

Heather, David

2016-07-01

Introduction: The Planetary Science Archive (PSA) is the European Space Agency's (ESA) repository of science data from all planetary science and exploration missions. The PSA provides access to scientific datasets through various interfaces (e.g. FTP browser, Map based, Advanced search, and Machine interface): http://archives.esac.esa.int/psa All datasets are scientifically peer-reviewed by independent scientists, and are compliant with the Planetary Data System (PDS) standards. Updating the PSA: The PSA is currently implementing a number of significant changes, both to its web-based interface to the scientific community, and to its database structure. The new PSA will be up-to-date with versions 3 and 4 of the PDS standards, as PDS4 will be used for ESA's upcoming ExoMars and BepiColombo missions. The newly designed PSA homepage will provide direct access to scientific datasets via a text search for targets or missions. This will significantly reduce the complexity for users to find their data and will promote one-click access to the datasets. Additionally, the homepage will provide direct access to advanced views and searches of the datasets. Users will have direct access to documentation, information and tools that are relevant to the scientific use of the dataset, including ancillary datasets, Software Interface Specification (SIS) documents, and any tools/help that the PSA team can provide. A login mechanism will provide additional functionalities to the users to aid / ease their searches (e.g. saving queries, managing default views). Queries to the PSA database will be possible either via the homepage (for simple searches of missions or targets), or through a filter menu for more tailored queries. The filter menu will offer multiple options to search for a particular dataset or product, and will manage queries for both in-situ and remote sensing instruments. Parameters such as start-time, phase angle, and heliocentric distance will be emphasized. A further

System level traffic shaping in disk servers with heterogeneous protocols

International Nuclear Information System (INIS)

Cano, Eric; Kruse, Daniele Francesco

2014-01-01

Disk access and tape migrations compete for network bandwidth in CASTORs disk servers, over various protocols: RFIO, Xroot, root and GridFTP. As there are a limited number of tape drives, it is important to keep them busy all the time, at their nominal speed. With potentially 100s of user read streams per server, the bandwidth for the tape migrations has to be guaranteed to a controlled level, and not the fair share the system gives by default. Xroot provides a prioritization mechanism, but using it implies moving exclusively to the Xroot protocol, which is not possible in short to mid-term time frame, as users are equally using all protocols. The greatest commonality of all those protocols is not more than the usage of TCP/IP. We investigated the Linux kernel traffic shaper to control TCP/ IP bandwidth. The performance and limitations of the traffic shaper have been understood in test environment, and satisfactory working point has been found for production. Notably, TCP offload engines' negative impact on traffic shaping, and the limitations of the length of the traffic shaping rules were discovered and measured. A suitable working point has been found and the traffic shaping is now successfully deployed in the CASTOR production systems at CERN. This system level approach could be transposed easily to other environments.

The EarthServer Federation: State, Role, and Contribution to GEOSS

Science.gov (United States)

Merticariu, Vlad; Baumann, Peter

2016-04-01

The intercontinental EarthServer initiative has established a European datacube platform with proven scalability: known databases exceed 100 TB, and single queries have been split across more than 1,000 cloud nodes. Its service interface being rigorously based on the OGC "Big Geo Data" standards, Web Coverage Service (WCS) and Web Coverage Processing Service (WCPS), a series of clients can dock into the services, ranging from open-source OpenLayers and QGIS over open-source NASA WorldWind to proprietary ESRI ArcGIS. Datacube fusion in a "mix and match" style is supported by the platform technolgy, the rasdaman Array Database System, which transparently federates queries so that users simply approach any node of the federation to access any data item, internally optimized for minimal data transfer. Notably, rasdaman is part of GEOSS GCI. NASA is contributing its Web WorldWind virtual globe for user-friendly data extraction, navigation, and analysis. Integrated datacube / metadata queries are contributed by CITE. Current federation members include ESA (managed by MEEO sr.l.), Plymouth Marine Laboratory (PML), the European Centre for Medium-Range Weather Forecast (ECMWF), Australia's National Computational Infrastructure, and Jacobs University (adding in Planetary Science). Further data centers have expressed interest in joining. We present the EarthServer approach, discuss its underlying technology, and illustrate the contribution this datacube platform can make to GEOSS.

CERN Document Server (CDS): Introduction

CERN Multimedia

CERN. Geneva; Costa, Flavio

2017-01-01

A short online tutorial introducing the CERN Document Server (CDS). Basic functionality description, the notion of Revisions and the CDS test environment. Links: CDS Production environment CDS Test environment  

ODISEES: A New Paradigm in Data Access

Science.gov (United States)

Huffer, E.; Little, M. M.; Kusterer, J.

2013-12-01

As part of its ongoing efforts to improve access to data, the Atmospheric Science Data Center has developed a high-precision Earth Science domain ontology (the 'ES Ontology') implemented in a graph database ('the Semantic Metadata Repository') that is used to store detailed, semantically-enhanced, parameter-level metadata for ASDC data products. The ES Ontology provides the semantic infrastructure needed to drive the ASDC's Ontology-Driven Interactive Search Environment for Earth Science ('ODISEES'), a data discovery and access tool, and will support additional data services such as analytics and visualization. The ES ontology is designed on the premise that naming conventions alone are not adequate to provide the information needed by prospective data consumers to assess the suitability of a given dataset for their research requirements; nor are current metadata conventions adequate to support seamless machine-to-machine interactions between file servers and end-user applications. Data consumers need information not only about what two data elements have in common, but also about how they are different. End-user applications need consistent, detailed metadata to support real-time data interoperability. The ES ontology is a highly precise, bottom-up, queriable model of the Earth Science domain that focuses on critical details about the measurable phenomena, instrument techniques, data processing methods, and data file structures. Earth Science parameters are described in detail in the ES Ontology and mapped to the corresponding variables that occur in ASDC datasets. Variables are in turn mapped to well-annotated representations of the datasets that they occur in, the instrument(s) used to create them, the instrument platforms, the processing methods, etc., creating a linked-data structure that allows both human and machine users to access a wealth of information critical to understanding and manipulating the data. The mappings are recorded in the Semantic Metadata

CVTree3 Web Server for Whole-genome-based and Alignment-free Prokaryotic Phylogeny and Taxonomy

Directory of Open Access Journals (Sweden)

Guanghong Zuo

2015-10-01

Full Text Available A faithful phylogeny and an objective taxonomy for prokaryotes should agree with each other and ultimately follow the genome data. With the number of sequenced genomes reaching tens of thousands, both tree inference and detailed comparison with taxonomy are great challenges. We now provide one solution in the latest Release 3.0 of the alignment-free and whole-genome-based web server CVTree3. The server resides in a cluster of 64 cores and is equipped with an interactive, collapsible, and expandable tree display. It is capable of comparing the tree branching order with prokaryotic classification at all taxonomic ranks from domains down to species and strains. CVTree3 allows for inquiry by taxon names and trial on lineage modifications. In addition, it reports a summary of monophyletic and non-monophyletic taxa at all ranks as well as produces print-quality subtree figures. After giving an overview of retrospective verification of the CVTree approach, the power of the new server is described for the mega-classification of prokaryotes and determination of taxonomic placement of some newly-sequenced genomes. A few discrepancies between CVTree and 16S rRNA analyses are also summarized with regard to possible taxonomic revisions. CVTree3 is freely accessible to all users at http://tlife.fudan.edu.cn/cvtree3/ without login requirements.

CVTree3 Web Server for Whole-genome-based and Alignment-free Prokaryotic Phylogeny and Taxonomy.

Science.gov (United States)

Zuo, Guanghong; Hao, Bailin

2015-10-01

A faithful phylogeny and an objective taxonomy for prokaryotes should agree with each other and ultimately follow the genome data. With the number of sequenced genomes reaching tens of thousands, both tree inference and detailed comparison with taxonomy are great challenges. We now provide one solution in the latest Release 3.0 of the alignment-free and whole-genome-based web server CVTree3. The server resides in a cluster of 64 cores and is equipped with an interactive, collapsible, and expandable tree display. It is capable of comparing the tree branching order with prokaryotic classification at all taxonomic ranks from domains down to species and strains. CVTree3 allows for inquiry by taxon names and trial on lineage modifications. In addition, it reports a summary of monophyletic and non-monophyletic taxa at all ranks as well as produces print-quality subtree figures. After giving an overview of retrospective verification of the CVTree approach, the power of the new server is described for the mega-classification of prokaryotes and determination of taxonomic placement of some newly-sequenced genomes. A few discrepancies between CVTree and 16S rRNA analyses are also summarized with regard to possible taxonomic revisions. CVTree3 is freely accessible to all users at http://tlife.fudan.edu.cn/cvtree3/ without login requirements. Copyright © 2015 The Authors. Production and hosting by Elsevier Ltd.. All rights reserved.

Instant Hyper-v Server Virtualization starter

CERN Document Server

Eguibar, Vicente Rodriguez

2013-01-01

Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks.The approach would be in a tutorial manner that will guide the users in an orderly manner toward virtualization.This book is conceived for system administrator and advanced PC enthusiasts who want to venture into the virtualization world. Although this book goes from scratch up, knowledge on server Operative Systems, LAN and networking has to be in place. Having a good background on server administration is desirable, including networking service

Look-ahead policies for admission to a single server loss system

NARCIS (Netherlands)

Nawijn, W.M.

1990-01-01

Consider a single server loss system in which the server, being idle, may reject or accept an arriving customer for service depending on the state at the arrival epoch. It is assumed that at every arrival epoch the server knows the service time of the arriving customer, the arrival time of the next

Sending servers to Morocco

CERN Multimedia

Joannah Caborn Wengler

2012-01-01

Did you know that computer centres are like people? They breathe air in and out like a person, they have to be kept at the right temperature, and they can even be organ donors. As part of a regular cycle of equipment renewal, the CERN Computer Centre has just donated 161 retired servers to universities in Morocco.   Prof. Abdeslam Hoummada and CERN DG Rolf Heuer seeing off the servers on the beginning of their journey to Morocco. “Many people don’t realise, but the Computer Centre is like a living thing. You don’t just install equipment and it runs forever. We’re continually replacing machines, broken parts and improving things like the cooling.” Wayne Salter, Leader of the IT Computing Facilities Group, watches over the Computer Centre a bit like a nurse monitoring a patient’s temperature, especially since new international recommendations for computer centre environmental conditions were released. “A new international s...

The IntFOLD server: an integrated web resource for protein fold recognition, 3D model quality assessment, intrinsic disorder prediction, domain prediction and ligand binding site prediction.

Science.gov (United States)

Roche, Daniel B; Buenavista, Maria T; Tetchner, Stuart J; McGuffin, Liam J

2011-07-01

The IntFOLD server is a novel independent server that integrates several cutting edge methods for the prediction of structure and function from sequence. Our guiding principles behind the server development were as follows: (i) to provide a simple unified resource that makes our prediction software accessible to all and (ii) to produce integrated output for predictions that can be easily interpreted. The output for predictions is presented as a simple table that summarizes all results graphically via plots and annotated 3D models. The raw machine readable data files for each set of predictions are also provided for developers, which comply with the Critical Assessment of Methods for Protein Structure Prediction (CASP) data standards. The server comprises an integrated suite of five novel methods: nFOLD4, for tertiary structure prediction; ModFOLD 3.0, for model quality assessment; DISOclust 2.0, for disorder prediction; DomFOLD 2.0 for domain prediction; and FunFOLD 1.0, for ligand binding site prediction. Predictions from the IntFOLD server were found to be competitive in several categories in the recent CASP9 experiment. The IntFOLD server is available at the following web site: http://www.reading.ac.uk/bioinf/IntFOLD/.

Supervisory control system implemented in programmable logical controller web server

OpenAIRE

Milavec, Simon

2012-01-01

In this thesis, we study the feasibility of supervisory control and data acquisition (SCADA) system realisation in a web server of a programmable logic controller. With the introduction of Ethernet protocol to the area of process control, the more powerful programmable logic controllers obtained integrated web servers. The web server of a programmable logic controller, produced by Siemens, will also be described in this thesis. Firstly, the software and the hardware equipment used for real...

Rclick: a web server for comparison of RNA 3D structures.

Science.gov (United States)

Nguyen, Minh N; Verma, Chandra

2015-03-15

RNA molecules play important roles in key biological processes in the cell and are becoming attractive for developing therapeutic applications. Since the function of RNA depends on its structure and dynamics, comparing and classifying the RNA 3D structures is of crucial importance to molecular biology. In this study, we have developed Rclick, a web server that is capable of superimposing RNA 3D structures by using clique matching and 3D least-squares fitting. Our server Rclick has been benchmarked and compared with other popular servers and methods for RNA structural alignments. In most cases, Rclick alignments were better in terms of structure overlap. Our server also recognizes conformational changes between structures. For this purpose, the server produces complementary alignments to maximize the extent of detectable similarity. Various examples showcase the utility of our web server for comparison of RNA, RNA-protein complexes and RNA-ligand structures. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Adventures in the evolution of a high-bandwidth network for central servers

International Nuclear Information System (INIS)

Swartz, K.L.; Cottrell, L.; Dart, M.

1994-08-01

In a small network, clients and servers may all be connected to a single Ethernet without significant performance concerns. As the number of clients on a network grows, the necessity of splitting the network into multiple sub-networks, each with a manageable number of clients, becomes clear. Less obvious is what to do with the servers. Group file servers on subnets and multihomed servers offer only partial solutions -- many other types of servers do not lend themselves to a decentralized model, and tend to collect on another, well-connected but overloaded Ethernet. The higher speed of FDDI seems to offer an easy solution, but in practice both expense and interoperability problems render FDDI a poor choice. Ethernet switches appear to permit cheaper and more reliable networking to the servers while providing an aggregate network bandwidth greater than a simple Ethernet. This paper studies the evolution of the server networks at SLAC. Difficulties encountered in the deployment of FDDI are described, as are the tools and techniques used to characterize the traffic patterns on the server network. Performance of Ethernet, FDDI, and switched Ethernet networks is analyzed, as are reliability and maintainability issues for these alternatives. The motivations for re-designing the SLAC general server network to use a switched Ethernet instead of FDDI are described, as are the reasons for choosing FDDI for the farm and firewall networks at SLAC. Guidelines are developed which may help in making this choice for other networks

Web mapping system for complex processing and visualization of environmental geospatial datasets

Science.gov (United States)

Titov, Alexander; Gordov, Evgeny; Okladnikov, Igor

2016-04-01

Environmental geospatial datasets (meteorological observations, modeling and reanalysis results, etc.) are used in numerous research applications. Due to a number of objective reasons such as inherent heterogeneity of environmental datasets, big dataset volume, complexity of data models used, syntactic and semantic differences that complicate creation and use of unified terminology, the development of environmental geodata access, processing and visualization services as well as client applications turns out to be quite a sophisticated task. According to general INSPIRE requirements to data visualization geoportal web applications have to provide such standard functionality as data overview, image navigation, scrolling, scaling and graphical overlay, displaying map legends and corresponding metadata information. It should be noted that modern web mapping systems as integrated geoportal applications are developed based on the SOA and might be considered as complexes of interconnected software tools for working with geospatial data. In the report a complex web mapping system including GIS web client and corresponding OGC services for working with geospatial (NetCDF, PostGIS) dataset archive is presented. There are three basic tiers of the GIS web client in it: 1. Tier of geospatial metadata retrieved from central MySQL repository and represented in JSON format 2. Tier of JavaScript objects implementing methods handling: --- NetCDF metadata --- Task XML object for configuring user calculations, input and output formats --- OGC WMS/WFS cartographical services 3. Graphical user interface (GUI) tier representing JavaScript objects realizing web application business logic Metadata tier consists of a number of JSON objects containing technical information describing geospatial datasets (such as spatio-temporal resolution, meteorological parameters, valid processing methods, etc). The middleware tier of JavaScript objects implementing methods for handling geospatial

Standby-Loss Elimination in Server Power Supply

Directory of Open Access Journals (Sweden)

Jong-Woo Kim

2017-07-01

Full Text Available In a server power system, a standby converter is required in order to provide the standby output, monitor the system’s status, and communicate with the server power system. Since these functions are always required, losses from the standby converter are produced even though the system operates in normal mode. For these reasons, the losses deteriorate the total efficiency of the system. In this paper, a new structure is proposed to eliminate the losses from the standby converter of a server power supply. The key feature of the proposed structure is that the main direct current (DC/DC converter substitutes all of the output power of the standby converter, and the standby converter is turned off in normal mode. With the proposed structure, the losses from the standby converter can be eliminated in normal mode, and this leads to a higher efficiency in overall load conditions. Although the structure has been proposed in the previous work, very important issues such as a steady state analysis, the transient responses, and how to control the standby converter are not discussed. This paper presents these issues further. The feasibility of the proposed structure has been verified with 400 V link voltage, 12 V/62.5 A main output, and a 12 V/2.1 A standby output server power system.

Client-server password recovery

NARCIS (Netherlands)

Chmielewski, Ł.; Hoepman, J.H.; Rossum, P. van

2009-01-01

Human memory is not perfect - people constantly memorize new facts and forget old ones. One example is forgetting a password, a common problem raised at IT help desks. We present several protocols that allow a user to automatically recover a password from a server using partial knowledge of the

A novel strategy to access high resolution DICOM medical images based on JPEG2000 interactive protocol

Science.gov (United States)

Tian, Yuan; Cai, Weihua; Sun, Jianyong; Zhang, Jianguo

2008-03-01

The demand for sharing medical information has kept rising. However, the transmission and displaying of high resolution medical images are limited if the network has a low transmission speed or the terminal devices have limited resources. In this paper, we present an approach based on JPEG2000 Interactive Protocol (JPIP) to browse high resolution medical images in an efficient way. We designed and implemented an interactive image communication system with client/server architecture and integrated it with Picture Archiving and Communication System (PACS). In our interactive image communication system, the JPIP server works as the middleware between clients and PACS servers. Both desktop clients and wireless mobile clients can browse high resolution images stored in PACS servers via accessing the JPIP server. The client can only make simple requests which identify the resolution, quality and region of interest and download selected portions of the JPEG2000 code-stream instead of downloading and decoding the entire code-stream. After receiving a request from a client, the JPIP server downloads the requested image from the PACS server and then responds the client by sending the appropriate code-stream. We also tested the performance of the JPIP server. The JPIP server runs stably and reliably under heavy load.

GSKY: A scalable distributed geospatial data server on the cloud

Science.gov (United States)

Rozas Larraondo, Pablo; Pringle, Sean; Antony, Joseph; Evans, Ben

2017-04-01

Earth systems, environmental and geophysical datasets are an extremely valuable sources of information about the state and evolution of the Earth. Being able to combine information coming from different geospatial collections is in increasing demand by the scientific community, and requires managing and manipulating data with different formats and performing operations such as map reprojections, resampling and other transformations. Due to the large data volume inherent in these collections, storing multiple copies of them is unfeasible and so such data manipulation must be performed on-the-fly using efficient, high performance techniques. Ideally this should be performed using a trusted data service and common system libraries to ensure wide use and reproducibility. Recent developments in distributed computing based on dynamic access to significant cloud infrastructure opens the door for such new ways of processing geospatial data on demand. The National Computational Infrastructure (NCI), hosted at the Australian National University (ANU), has over 10 Petabytes of nationally significant research data collections. Some of these collections, which comprise a variety of observed and modelled geospatial data, are now made available via a highly distributed geospatial data server, called GSKY (pronounced [jee-skee]). GSKY supports on demand processing of large geospatial data products such as satellite earth observation data as well as numerical weather products, allowing interactive exploration and analysis of the data. It dynamically and efficiently distributes the required computations among cloud nodes providing a scalable analysis framework that can adapt to serve large number of concurrent users. Typical geospatial workflows handling different file formats and data types, or blending data in different coordinate projections and spatio-temporal resolutions, is handled transparently by GSKY. This is achieved by decoupling the data ingestion and indexing process as

Conversation Threads Hidden within Email Server Logs

Science.gov (United States)

Palus, Sebastian; Kazienko, Przemysław

Email server logs contain records of all email Exchange through this server. Often we would like to analyze those emails not separately but in conversation thread, especially when we need to analyze social network extracted from those email logs. Unfortunately each mail is in different record and those record are not tided to each other in any obvious way. In this paper method for discussion threads extraction was proposed together with experiments on two different data sets - Enron and WrUT..

Microsoft® Exchange Server 2007 Administrator's Companion

CERN Document Server

Glenn, Walter; Maher, Joshua

2009-01-01

Get your mission-critical messaging and collaboration systems up and running with the essential guide to deploying and managing Exchange Server 2007, now updated for SP1. This comprehensive administrator's reference covers the full range of server and client deployments, unified communications, security features, performance optimization, troubleshooting, and disaster recovery. It also includes four chapters on security policy, tools, and techniques to help protect messaging systems from viruses, spam, and phishing. Written by expert authors Walter Glenn and Scott Lowe, this reference deliver

dAPE: a web server to detect homorepeats and follow their evolution.

Science.gov (United States)

Mier, Pablo; Andrade-Navarro, Miguel A

2017-04-15

Homorepeats are low complexity regions consisting of repetitions of a single amino acid residue. There is no current consensus on the minimum number of residues needed to define a functional homorepeat, nor even if mismatches are allowed. Here we present dAPE, a web server that helps following the evolution of homorepeats based on orthology information, using a sensitive but tunable cutoff to help in the identification of emerging homorepeats. dAPE can be accessed from http://cbdm-01.zdv.uni-mainz.de/∼munoz/polyx . munoz@uni-mainz.de. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

Middleware for multi-client and multi-server mobile applications

NARCIS (Netherlands)

Rocha, B.P.S.; Rezende, C.G.; Loureiro, A.A.F.

2007-01-01

With popularization of mobile computing, many developers have faced problems due to great heterogeneity of devices. To address this issue, we present in this work a middleware for multi-client and multi-server mobile applications. We assume that the middleware at the server side has no resource

Monday 9 January 2006: RESTRICTED ACCESS to the Technical Network

CERN Multimedia

CNIC Users Exchange and IT/CS

2005-01-01

As of Monday 9 January 2006, Ethernet access from the general CERN network to the Technical Network (TN) will be restricted in order to improve security on the TN. As a result, all Ethernet communication between the General Purpose Network (GPN) and the TN will be filtered. Only communication lines to the general IT services such as DNS, TP, NICE, DFS, AFS, Antivirus, Linux installation servers, License servers, OracleDB, TSM backup servers and dedicated AB and TS servers on the GPN will remain open. Please make sure that all your devices are registered properly in the network database (LANDB): http://network.cern.ch/. You are encouraged to make proper use of the 'Tag' and 'Description' fields in order to identify your system later on. If your system depends on special services on the GPN or is split between the GPN and the TN, e.g. consists of devices (PCs, PLCs, VME crates, webcams, etc.) connected to both the TN and the GPN, please contact the Technical-Network.Administrator@cern.ch . They will include...

2MASS Catalog Server Kit Version 2.1

Science.gov (United States)

Yamauchi, C.

2013-10-01

The 2MASS Catalog Server Kit is open source software for use in easily constructing a high performance search server for important astronomical catalogs. This software utilizes the open source RDBMS PostgreSQL, therefore, any users can setup the database on their local computers by following step-by-step installation guide. The kit provides highly optimized stored functions for positional searchs similar to SDSS SkyServer. Together with these, the powerful SQL environment of PostgreSQL will meet various user's demands. We released 2MASS Catalog Server Kit version 2.1 in 2012 May, which supports the latest WISE All-Sky catalog (563,921,584 rows) and 9 major all-sky catalogs. Local databases are often indispensable for observatories with unstable or narrow-band networks or severe use, such as retrieving large numbers of records within a small period of time. This software is the best for such purposes, and increasing supported catalogs and improvements of version 2.1 can cover a wider range of applications including advanced calibration system, scientific studies using complicated SQL queries, etc. Official page: http://www.ir.isas.jaxa.jp/~cyamauch/2masskit/

Client-Server Password Recovery

NARCIS (Netherlands)

Chmielewski, L.; Hoepman, J.H.; Rossum, P. van

2009-01-01

Human memory is not perfect – people constantly memorize new facts and forget old ones. One example is forgetting a password, a common problem raised at IT help desks. We present several protocols that allow a user to automatically recover a password from a server using partial knowledge of the

Implementation of an Embedded Web Server Application for Wireless Control of Brain Computer Interface Based Home Environments.

Science.gov (United States)

Aydın, Eda Akman; Bay, Ömer Faruk; Güler, İnan

2016-01-01

Brain Computer Interface (BCI) based environment control systems could facilitate life of people with neuromuscular diseases, reduces dependence on their caregivers, and improves their quality of life. As well as easy usage, low-cost, and robust system performance, mobility is an important functionality expected from a practical BCI system in real life. In this study, in order to enhance users' mobility, we propose internet based wireless communication between BCI system and home environment. We designed and implemented a prototype of an embedded low-cost, low power, easy to use web server which is employed in internet based wireless control of a BCI based home environment. The embedded web server provides remote access to the environmental control module through BCI and web interfaces. While the proposed system offers to BCI users enhanced mobility, it also provides remote control of the home environment by caregivers as well as the individuals in initial stages of neuromuscular disease. The input of BCI system is P300 potentials. We used Region Based Paradigm (RBP) as stimulus interface. Performance of the BCI system is evaluated on data recorded from 8 non-disabled subjects. The experimental results indicate that the proposed web server enables internet based wireless control of electrical home appliances successfully through BCIs.

Web servers and services for electrostatics calculations with APBS and PDB2PQR

Science.gov (United States)

Unni, Samir; Huang, Yong; Hanson, Robert; Tobias, Malcolm; Krishnan, Sriram; Li, Wilfred W.; Nielsen, Jens E.; Baker, Nathan A.

2011-01-01

APBS and PDB2PQR are widely utilized free software packages for biomolecular electrostatics calculations. Using the Opal toolkit, we have developed a Web services framework for these software packages that enables the use of APBS and PDB2PQR by users who do not have local access to the necessary amount of computational capabilities. This not only increases accessibility of the software to a wider range of scientists, educators, and students but it also increases the availability of electrostatics calculations on portable computing platforms. Users can access this new functionality in two ways. First, an Opal-enabled version of APBS is provided in current distributions, available freely on the web. Second, we have extended the PDB2PQR web server to provide an interface for the setup, execution, and visualization electrostatics potentials as calculated by APBS. This web interface also uses the Opal framework which ensures the scalability needed to support the large APBS user community. Both of these resources are available from the APBS/PDB2PQR website: http://www.poissonboltzmann.org/. PMID:21425296

DoS attacks targeting SIP server and improvements of robustness

OpenAIRE

Vozňák, Miroslav; Šafařík, Jakub

2012-01-01

The paper describes the vulnerability of SIP servers to DoS attacks and methods for server protection. For each attack, this paper describes their impact on a SIP server, evaluation of the threat and the way in which they are executed. Attacks are described in detail, and a security precaution is made to prevent each of them. The proposed solution of the protection is based on a specific topology of an intrusion protection systems components consisting of a combination of...

An Array Library for Microsoft SQL Server with Astrophysical Applications

Science.gov (United States)

Dobos, L.; Szalay, A. S.; Blakeley, J.; Falck, B.; Budavári, T.; Csabai, I.

2012-09-01

Today's scientific simulations produce output on the 10-100 TB scale. This unprecedented amount of data requires data handling techniques that are beyond what is used for ordinary files. Relational database systems have been successfully used to store and process scientific data, but the new requirements constantly generate new challenges. Moving terabytes of data among servers on a timely basis is a tough problem, even with the newest high-throughput networks. Thus, moving the computations as close to the data as possible and minimizing the client-server overhead are absolutely necessary. At least data subsetting and preprocessing have to be done inside the server process. Out of the box commercial database systems perform very well in scientific applications from the prospective of data storage optimization, data retrieval, and memory management but lack basic functionality like handling scientific data structures or enabling advanced math inside the database server. The most important gap in Microsoft SQL Server is the lack of a native array data type. Fortunately, the technology exists to extend the database server with custom-written code that enables us to address these problems. We present the prototype of a custom-built extension to Microsoft SQL Server that adds array handling functionality to the database system. With our Array Library, fix-sized arrays of all basic numeric data types can be created and manipulated efficiently. Also, the library is designed to be able to be seamlessly integrated with the most common math libraries, such as BLAS, LAPACK, FFTW, etc. With the help of these libraries, complex operations, such as matrix inversions or Fourier transformations, can be done on-the-fly, from SQL code, inside the database server process. We are currently testing the prototype with two different scientific data sets: The Indra cosmological simulation will use it to store particle and density data from N-body simulations, and the Milky Way Laboratory

F2AC: A Lightweight, Fine-Grained, and Flexible Access Control Scheme for File Storage in Mobile Cloud Computing

Directory of Open Access Journals (Sweden)

Wei Ren

2016-01-01

Full Text Available Current file storage service models for cloud servers assume that users either belong to single layer with different privileges or cannot authorize privileges iteratively. Thus, the access control is not fine-grained and flexible. Besides, most access control methods at cloud servers mainly rely on computationally intensive cryptographic algorithms and, especially, may not be able to support highly dynamic ad hoc groups with addition and removal of group members. In this paper, we propose a scheme called F2AC, which is a lightweight, fine-grained, and flexible access control scheme for file storage in mobile cloud computing. F2AC can not only achieve iterative authorization, authentication with tailored policies, and access control for dynamically changing accessing groups, but also provide access privilege transition and revocation. A new access control model called directed tree with linked leaf model is proposed for further implementations in data structures and algorithms. The extensive analysis is given for justifying the soundness and completeness of F2AC.

A Java class library for accessing Cadplan data

International Nuclear Information System (INIS)

Zagler, Norbert

2008-01-01

A Java class library was developed to be able to access the data of the treatment planning system Varian Cadplan which was decommissioned in 2005. The library reads and encapsulates the most important patient data. It facilitates creating viewing software for CT slices, contours and isodoses. Keeping alive old Cadplan hardware is no longer necessary. The files can be stored on any server in the network of a department and they can be accessed from any workstation capable of running Java software. (orig.)

GenomeRunner web server: regulatory similarity and differences define the functional impact of SNP sets.

Science.gov (United States)

Dozmorov, Mikhail G; Cara, Lukas R; Giles, Cory B; Wren, Jonathan D

2016-08-01

The growing amount of regulatory data from the ENCODE, Roadmap Epigenomics and other consortia provides a wealth of opportunities to investigate the functional impact of single nucleotide polymorphisms (SNPs). Yet, given the large number of regulatory datasets, researchers are posed with a challenge of how to efficiently utilize them to interpret the functional impact of SNP sets. We developed the GenomeRunner web server to automate systematic statistical analysis of SNP sets within a regulatory context. Besides defining the functional impact of SNP sets, GenomeRunner implements novel regulatory similarity/differential analyses, and cell type-specific regulatory enrichment analysis. Validated against literature- and disease ontology-based approaches, analysis of 39 disease/trait-associated SNP sets demonstrated that the functional impact of SNP sets corresponds to known disease relationships. We identified a group of autoimmune diseases with SNPs distinctly enriched in the enhancers of T helper cell subpopulations, and demonstrated relevant cell type-specificity of the functional impact of other SNP sets. In summary, we show how systematic analysis of genomic data within a regulatory context can help interpreting the functional impact of SNP sets. GenomeRunner web server is freely available at http://www.integrativegenomics.org/ mikhail.dozmorov@gmail.com Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Note on a tandem queue with delayed server release

NARCIS (Netherlands)

Nawijn, W.M.

2000-01-01

We consider a tandem queue with two stations. The first station is an $s$-server queue with Poisson arrivals and exponential service times. After terminating his service in the first station, a customer enters the second station to require service at a single server, while in the meantime he is

A tandem queue with server slow-down and blocking

NARCIS (Netherlands)

van Foreest, N.D.; van Ommeren, Jan C.W.; Mandjes, M.R.H.; Scheinhardt, Willem R.W.

2005-01-01

We consider two variants of a two-station tandem network with blocking. In both variants the first server ceases to work when the queue length at the second station hits a 'blocking threshold.' In addition, in variant 2 the first server decreases its service rate when the second queue exceeds a

A tandem queue with server slow-down and blocking.

NARCIS (Netherlands)

van Foreest, N.; van Ommeren, J.C.; Mandjes, M.R.H.; Scheinhardt, W.

2005-01-01

We consider two variants of a two-station tandem network with blocking. In both variants the first server ceases to work when the queue length at the second station hits a 'blocking threshold.' In addition, in variant 2 the first server decreases its service rate when the second queue exceeds a

Secure Server Login by Using Third Party and Chaotic System

Science.gov (United States)

Abdulatif, Firas A.; zuhiar, Maan

2018-05-01

Server is popular among all companies and it used by most of them but due to the security threat on the server make this companies are concerned when using it so that in this paper we will design a secure system based on one time password and third parity authentication (smart phone). The proposed system make security to the login process of server by using one time password to authenticate person how have permission to login and third parity device (smart phone) as other level of security.

MultiSETTER: web server for multiple RNA structure comparison.

Science.gov (United States)

Čech, Petr; Hoksza, David; Svozil, Daniel

2015-08-12

Understanding the architecture and function of RNA molecules requires methods for comparing and analyzing their tertiary and quaternary structures. While structural superposition of short RNAs is achievable in a reasonable time, large structures represent much bigger challenge. Therefore, we have developed a fast and accurate algorithm for RNA pairwise structure superposition called SETTER and implemented it in the SETTER web server. However, though biological relationships can be inferred by a pairwise structure alignment, key features preserved by evolution can be identified only from a multiple structure alignment. Thus, we extended the SETTER algorithm to the alignment of multiple RNA structures and developed the MultiSETTER algorithm. In this paper, we present the updated version of the SETTER web server that implements a user friendly interface to the MultiSETTER algorithm. The server accepts RNA structures either as the list of PDB IDs or as user-defined PDB files. After the superposition is computed, structures are visualized in 3D and several reports and statistics are generated. To the best of our knowledge, the MultiSETTER web server is the first publicly available tool for a multiple RNA structure alignment. The MultiSETTER server offers the visual inspection of an alignment in 3D space which may reveal structural and functional relationships not captured by other multiple alignment methods based either on a sequence or on secondary structure motifs.

Testing an Open Source installation and server provisioning tool for the INFN CNAF Tierl Storage system

International Nuclear Information System (INIS)

Pezzi, M; Favaro, M; Gregori, D; Ricci, P P; Sapunenko, V

2014-01-01

In large computing centers, such as the INFN CNAF Tier1 [1], is essential to be able to configure all the machines, depending on use, in an automated way. For several years at the Tier1 has been used Quattor[2], a server provisioning tool, which is currently used in production. Nevertheless we have recently started a comparison study involving other tools able to provide specific server installation and configuration features and also offer a proper full customizable solution as an alternative to Quattor. Our choice at the moment fell on integration between two tools: Cobbler [3] for the installation phase and Puppet [4] for the server provisioning and management operation. The tool should provide the following properties in order to replicate and gradually improve the current system features: implement a system check for storage specific constraints such as kernel modules black list at boot time to avoid undesired SAN (Storage Area Network) access during disk partitioning; a simple and effective mechanism for kernel upgrade and downgrade; the ability of setting package provider using yum, rpm or apt; easy to use Virtual Machine installation support including bonding and specific Ethernet configuration; scalability for managing thousands of nodes and parallel installations. This paper describes the results of the comparison and the tests carried out to verify the requirements and the new system suitability in the INFN-T1 environment.

Neutralizing SQL Injection Attack Using Server Side Code Modification in Web Applications

Directory of Open Access Journals (Sweden)

Asish Kumar Dalai

2017-01-01

Full Text Available Reports on web application security risks show that SQL injection is the top most vulnerability. The journey of static to dynamic web pages leads to the use of database in web applications. Due to the lack of secure coding techniques, SQL injection vulnerability prevails in a large set of web applications. A successful SQL injection attack imposes a serious threat to the database, web application, and the entire web server. In this article, the authors have proposed a novel method for prevention of SQL injection attack. The classification of SQL injection attacks has been done based on the methods used to exploit this vulnerability. The proposed method proves to be efficient in the context of its ability to prevent all types of SQL injection attacks. Some popular SQL injection attack tools and web application security datasets have been used to validate the model. The results obtained are promising with a high accuracy rate for detection of SQL injection attack.

Content sensitivity based access control framework for Hadoop

Directory of Open Access Journals (Sweden)

T.K. Ashwin Kumar

2017-11-01

Full Text Available Big data technologies have seen tremendous growth in recent years. They are widely used in both industry and academia. In spite of such exponential growth, these technologies lack adequate measures to protect data from misuse/abuse. Corporations that collect data from multiple sources are at risk of liabilities due to the exposure of sensitive information. In the current implementation of Hadoop, only file-level access control is feasible. Providing users with the ability to access data based on the attributes in a dataset or the user’s role is complicated because of the sheer volume and multiple formats (structured, unstructured and semi-structured of data. In this paper, we propose an access control framework, which enforces access control policies dynamically based on the sensitivity of the data. This framework enforces access control policies by harnessing the data context, usage patterns and information sensitivity. Information sensitivity changes over time with the addition and removal of datasets, which can lead to modifications in access control decisions. The proposed framework accommodates these changes. The proposed framework is automated to a large extent as the data itself determines the sensitivity with minimal user intervention. Our experimental results show that the proposed framework is capable of enforcing access control policies on non-multimedia datasets with minimal overhead.

An electrical load measurements dataset of United Kingdom households from a two-year longitudinal study.

Science.gov (United States)

Murray, David; Stankovic, Lina; Stankovic, Vladimir

2017-01-05

Smart meter roll-outs provide easy access to granular meter measurements, enabling advanced energy services, ranging from demand response measures, tailored energy feedback and smart home/building automation. To design such services, train and validate models, access to data that resembles what is expected of smart meters, collected in a real-world setting, is necessary. The REFIT electrical load measurements dataset described in this paper includes whole house aggregate loads and nine individual appliance measurements at 8-second intervals per house, collected continuously over a period of two years from 20 houses. During monitoring, the occupants were conducting their usual routines. At the time of publishing, the dataset has the largest number of houses monitored in the United Kingdom at less than 1-minute intervals over a period greater than one year. The dataset comprises 1,194,958,790 readings, that represent over 250,000 monitored appliance uses. The data is accessible in an easy-to-use comma-separated format, is time-stamped and cleaned to remove invalid measurements, correctly label appliance data and fill in small gaps of missing data.

An electrical load measurements dataset of United Kingdom households from a two-year longitudinal study

Science.gov (United States)

Murray, David; Stankovic, Lina; Stankovic, Vladimir

2017-01-01

Smart meter roll-outs provide easy access to granular meter measurements, enabling advanced energy services, ranging from demand response measures, tailored energy feedback and smart home/building automation. To design such services, train and validate models, access to data that resembles what is expected of smart meters, collected in a real-world setting, is necessary. The REFIT electrical load measurements dataset described in this paper includes whole house aggregate loads and nine individual appliance measurements at 8-second intervals per house, collected continuously over a period of two years from 20 houses. During monitoring, the occupants were conducting their usual routines. At the time of publishing, the dataset has the largest number of houses monitored in the United Kingdom at less than 1-minute intervals over a period greater than one year. The dataset comprises 1,194,958,790 readings, that represent over 250,000 monitored appliance uses. The data is accessible in an easy-to-use comma-separated format, is time-stamped and cleaned to remove invalid measurements, correctly label appliance data and fill in small gaps of missing data.

The CMS dataset bookkeeping service

Science.gov (United States)

Afaq, A.; Dolgert, A.; Guo, Y.; Jones, C.; Kosyakov, S.; Kuznetsov, V.; Lueking, L.; Riley, D.; Sekhri, V.

2008-07-01

The CMS Dataset Bookkeeping Service (DBS) has been developed to catalog all CMS event data from Monte Carlo and Detector sources. It provides the ability to identify MC or trigger source, track data provenance, construct datasets for analysis, and discover interesting data. CMS requires processing and analysis activities at various service levels and the DBS system provides support for localized processing or private analysis, as well as global access for CMS users at large. Catalog entries can be moved among the various service levels with a simple set of migration tools, thus forming a loose federation of databases. DBS is available to CMS users via a Python API, Command Line, and a Discovery web page interfaces. The system is built as a multi-tier web application with Java servlets running under Tomcat, with connections via JDBC to Oracle or MySQL database backends. Clients connect to the service through HTTP or HTTPS with authentication provided by GRID certificates and authorization through VOMS. DBS is an integral part of the overall CMS Data Management and Workflow Management systems.

The CMS dataset bookkeeping service

Energy Technology Data Exchange (ETDEWEB)

Afaq, A; Guo, Y; Kosyakov, S; Lueking, L; Sekhri, V [Fermilab, Batavia, Illinois 60510 (United States); Dolgert, A; Jones, C; Kuznetsov, V; Riley, D [Cornell University, Ithaca, New York 14850 (United States)

2008-07-15

The CMS Dataset Bookkeeping Service (DBS) has been developed to catalog all CMS event data from Monte Carlo and Detector sources. It provides the ability to identify MC or trigger source, track data provenance, construct datasets for analysis, and discover interesting data. CMS requires processing and analysis activities at various service levels and the DBS system provides support for localized processing or private analysis, as well as global access for CMS users at large. Catalog entries can be moved among the various service levels with a simple set of migration tools, thus forming a loose federation of databases. DBS is available to CMS users via a Python API, Command Line, and a Discovery web page interfaces. The system is built as a multi-tier web application with Java servlets running under Tomcat, with connections via JDBC to Oracle or MySQL database backends. Clients connect to the service through HTTP or HTTPS with authentication provided by GRID certificates and authorization through VOMS. DBS is an integral part of the overall CMS Data Management and Workflow Management systems.

The CMS dataset bookkeeping service

International Nuclear Information System (INIS)

Afaq, A; Guo, Y; Kosyakov, S; Lueking, L; Sekhri, V; Dolgert, A; Jones, C; Kuznetsov, V; Riley, D

2008-01-01

The CMS Dataset Bookkeeping Service (DBS) has been developed to catalog all CMS event data from Monte Carlo and Detector sources. It provides the ability to identify MC or trigger source, track data provenance, construct datasets for analysis, and discover interesting data. CMS requires processing and analysis activities at various service levels and the DBS system provides support for localized processing or private analysis, as well as global access for CMS users at large. Catalog entries can be moved among the various service levels with a simple set of migration tools, thus forming a loose federation of databases. DBS is available to CMS users via a Python API, Command Line, and a Discovery web page interfaces. The system is built as a multi-tier web application with Java servlets running under Tomcat, with connections via JDBC to Oracle or MySQL database backends. Clients connect to the service through HTTP or HTTPS with authentication provided by GRID certificates and authorization through VOMS. DBS is an integral part of the overall CMS Data Management and Workflow Management systems

The CMS dataset bookkeeping service

International Nuclear Information System (INIS)

Afaq, Anzar; Dolgert, Andrew; Guo, Yuyi; Jones, Chris; Kosyakov, Sergey; Kuznetsov, Valentin; Lueking, Lee; Riley, Dan; Sekhri, Vijay

2007-01-01

The CMS Dataset Bookkeeping Service (DBS) has been developed to catalog all CMS event data from Monte Carlo and Detector sources. It provides the ability to identify MC or trigger source, track data provenance, construct datasets for analysis, and discover interesting data. CMS requires processing and analysis activities at various service levels and the DBS system provides support for localized processing or private analysis, as well as global access for CMS users at large. Catalog entries can be moved among the various service levels with a simple set of migration tools, thus forming a loose federation of databases. DBS is available to CMS users via a Python API, Command Line, and a Discovery web page interfaces. The system is built as a multi-tier web application with Java servlets running under Tomcat, with connections via JDBC to Oracle or MySQL database backends. Clients connect to the service through HTTP or HTTPS with authentication provided by GRID certificates and authorization through VOMS. DBS is an integral part of the overall CMS Data Management and Workflow Management systems

Saving Money and Time with Virtual Server

CERN Document Server

Sanders, Chris

2006-01-01

Microsoft Virtual Server 2005 consistently proves to be worth its weight in gold, with new implementations thought up every day. With this product now a free download from Microsoft, scores of new users are able to experience what the power of virtualization can do for their networks. This guide is aimed at network administrators who are interested in ways that Virtual Server 2005 can be implemented in their organizations in order to save money and increase network productivity. It contains information on setting up a virtual network, virtual consolidation, virtual security, virtual honeypo

The M/G/1 queue with quasi-restricted accessibility

NARCIS (Netherlands)

Boxma, O.J.; Perry, D.; Stadje, W.; Zacks, S.

2009-01-01

We consider single-server queues of the M/G/1 kind with a special kind of partial customer rejection called quasi-restricted accessibility (QRA). Under QRA, the actual service time assigned to an arriving customer depends on his service requirement, say x, the current workload, say w, and a

A Graphical Client-Server Approach to Financial Management

CERN Document Server

Möller, M

1994-01-01

At the European Laboratory for Particle Physics (CERN), we have an annual budget of around 600 million US dollars. In order to manage this budget successfully, fast, accurate and easy information access is required throughout the management hierarchy. To meet these goals we have focused on the powerful combination of Relational Database Technology, Fourth Generation Tools and Client-Server architecture. Using these technologies we have developed a powerful and easy-to-use management information tool (known as the BHT) which allows the follow up and tracking of expenditure at all levels throughout the organization. Executives may instantaneously produce up-to-date graphics showing the expenditure profile of the organization. These graphics may then be used as a basis for ‘zooming in’ to view more and more details until the individual financial transactions are reached (all of which are on-line and available on the user’s desktop). The graphical user interface runs on both Macintosh and PC. Using ORACLE�...

Facing the Challenges of Accessing, Managing, and Integrating Large Observational Datasets in Ecology: Enabling and Enriching the Use of NEON's Observational Data

Science.gov (United States)

Thibault, K. M.

2013-12-01

As the construction of NEON and its transition to operations progresses, more and more data will become available to the scientific community, both from NEON directly and from the concomitant growth of existing data repositories. Many of these datasets include ecological observations of a diversity of taxa in both aquatic and terrestrial environments. Although observational data have been collected and used throughout the history of organismal biology, the field has not yet fully developed a culture of data management, documentation, standardization, sharing and discoverability to facilitate the integration and synthesis of datasets. Moreover, the tools required to accomplish these goals, namely database design, implementation, and management, and automation and parallelization of analytical tasks through computational techniques, have not historically been included in biology curricula, at either the undergraduate or graduate levels. To ensure the success of data-generating projects like NEON in advancing organismal ecology and to increase transparency and reproducibility of scientific analyses, an acceleration of the cultural shift to open science practices, the development and adoption of data standards, such as the DarwinCore standard for taxonomic data, and increased training in computational approaches for biologists need to be realized. Here I highlight several initiatives that are intended to increase access to and discoverability of publicly available datasets and equip biologists and other scientists with the skills that are need to manage, integrate, and analyze data from multiple large-scale projects. The EcoData Retriever (ecodataretriever.org) is a tool that downloads publicly available datasets, re-formats the data into an efficient relational database structure, and then automatically imports the data tables onto a user's local drive into the database tool of the user's choice. The automation of these tasks results in nearly instantaneous execution

LHCb: Fabric Management with Diskless Servers and Quattor on LHCb

CERN Multimedia

Schweitzer, P; Brarda, L; Neufeld, N

2011-01-01

Large scientific experiments nowadays very often are using large computer farms to process the events acquired from the detectors. In LHCb a small sysadmin team manages 1400 servers of the LHCb Event Filter Farm, but also a wide variety of control servers for the detector electronics and infrastructure computers: file servers, gateways, DNS, DHCP and others. This variety of servers could not be handled without a solid fabric management system. We choose the Quattor toolkit for this task. We will present our use of this toolkit, with an emphasis on how we handle our diskless nodes (Event filter farm nodes and computers embedded in the acquisition electronic cards). We will show our current tests to replace the standard (RedHat/Scientific Linux) way of handling diskless nodes to fusion filesystems and how it improves fabric management.

Microsoft SQL Server 2012 Business Intelligence ja sen tuomat uudistukset

OpenAIRE

Luoma, Lauri

2013-01-01

Insinöörityö käsittelee Metropolia Ammattikorkeakoulun Microsoft Business Intelligence (BI) ratkaisut -kurssilla käytetyn laboratoriomanuaalin MCTS Self-Paced Training Kit (Exam 70-448) -harjoituksien siirtämistä SQL Serverille 2012. Työllä on tarkoitus osoittaa, että SQL Server 2012 BI -työkalut soveltuvat harjoituksiin. Työssä siirrytään käyttämään uudempaa työkalua, SQL Server Data Toolsia, joka korvaa SQL Server 2008 R2 Business Intelligence Development Studion. Työn alussa tutust...

Energy Servers Deliver Clean, Affordable Power

Science.gov (United States)

2010-01-01

K.R. Sridhar developed a fuel cell device for Ames Research Center, that could use solar power to split water into oxygen for breathing and hydrogen for fuel on Mars. Sridhar saw the potential of the technology, when reversed, to create clean energy on Earth. He founded Bloom Energy, of Sunnyvale, California, to advance the technology. Today, the Bloom Energy Server is providing cost-effective, environmentally friendly energy to a host of companies such as eBay, Google, and The Coca-Cola Company. Bloom's NASA-derived Energy Servers generate energy that is about 67-percent cleaner than a typical coal-fired power plant when using fossil fuels and 100-percent cleaner with renewable fuels.

BLAST-EXPLORER helps you building datasets for phylogenetic analysis

Directory of Open Access Journals (Sweden)

Claverie Jean-Michel

2010-01-01

Full Text Available Abstract Background The right sampling of homologous sequences for phylogenetic or molecular evolution analyses is a crucial step, the quality of which can have a significant impact on the final interpretation of the study. There is no single way for constructing datasets suitable for phylogenetic analysis, because this task intimately depends on the scientific question we want to address, Moreover, database mining softwares such as BLAST which are routinely used for searching homologous sequences are not specifically optimized for this task. Results To fill this gap, we designed BLAST-Explorer, an original and friendly web-based application that combines a BLAST search with a suite of tools that allows interactive, phylogenetic-oriented exploration of the BLAST results and flexible selection of homologous sequences among the BLAST hits. Once the selection of the BLAST hits is done using BLAST-Explorer, the corresponding sequence can be imported locally for external analysis or passed to the phylogenetic tree reconstruction pipelines available on the Phylogeny.fr platform. Conclusions BLAST-Explorer provides a simple, intuitive and interactive graphical representation of the BLAST results and allows selection and retrieving of the BLAST hit sequences based a wide range of criterions. Although BLAST-Explorer primarily aims at helping the construction of sequence datasets for further phylogenetic study, it can also be used as a standard BLAST server with enriched output. BLAST-Explorer is available at http://www.phylogeny.fr

Discovery and Reuse of Open Datasets: An Exploratory Study

Directory of Open Access Journals (Sweden)

Sara

2016-07-01

Full Text Available Objective: This article analyzes twenty cited or downloaded datasets and the repositories that house them, in order to produce insights that can be used by academic libraries to encourage discovery and reuse of research data in institutional repositories. Methods: Using Thomson Reuters’ Data Citation Index and repository download statistics, we identified twenty cited/downloaded datasets. We documented the characteristics of the cited/downloaded datasets and their corresponding repositories in a self-designed rubric. The rubric includes six major categories: basic information; funding agency and journal information; linking and sharing; factors to encourage reuse; repository characteristics; and data description. Results: Our small-scale study suggests that cited/downloaded datasets generally comply with basic recommendations for facilitating reuse: data are documented well; formatted for use with a variety of software; and shared in established, open access repositories. Three significant factors also appear to contribute to dataset discovery: publishing in discipline-specific repositories; indexing in more than one location on the web; and using persistent identifiers. The cited/downloaded datasets in our analysis came from a few specific disciplines, and tended to be funded by agencies with data publication mandates. Conclusions: The results of this exploratory research provide insights that can inform academic librarians as they work to encourage discovery and reuse of institutional datasets. Our analysis also suggests areas in which academic librarians can target open data advocacy in their communities in order to begin to build open data success stories that will fuel future advocacy efforts.

Security Mechanism Based on Hospital Authentication Server for Secure Application of Implantable Medical Devices

Science.gov (United States)

2014-01-01

After two recent security attacks against implantable medical devices (IMDs) have been reported, the privacy and security risks of IMDs have been widely recognized in the medical device market and research community, since the malfunctioning of IMDs might endanger the patient's life. During the last few years, a lot of researches have been carried out to address the security-related issues of IMDs, including privacy, safety, and accessibility issues. A physician accesses IMD through an external device called a programmer, for diagnosis and treatment. Hence, cryptographic key management between IMD and programmer is important to enforce a strict access control. In this paper, a new security architecture for the security of IMDs is proposed, based on a 3-Tier security model, where the programmer interacts with a Hospital Authentication Server, to get permissions to access IMDs. The proposed security architecture greatly simplifies the key management between IMDs and programmers. Also proposed is a security mechanism to guarantee the authenticity of the patient data collected from IMD and the nonrepudiation of the physician's treatment based on it. The proposed architecture and mechanism are analyzed and compared with several previous works, in terms of security and performance. PMID:25276797

Security mechanism based on Hospital Authentication Server for secure application of implantable medical devices.

Science.gov (United States)

Park, Chang-Seop