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Sample records for sea slug onchidium

  1. A new photosensory function for simple photoreceptors, the intrinsically photoresponsive neurons of the sea slug Onchidium

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    Tsukasa Gotow

    2009-12-01

    Full Text Available Simple photoreceptors, namely intrinsically light-sensitive neurons without microvilli and/or cilia, have long been known to exist in the central ganglia of crayfish, Aplysia, Onchidium, and Helix. These simple photoreceptors are not only first-order photosensory cells, but also second-order neurons (interneurons, relaying several kinds of sensory synaptic inputs. Another important issue is that the photoresponses of these simple photoreceptors show very slow kinetics and little adaptation. These characteristics suggest that the simple photoreceptors of the Onchidium have a function in non-image-forming vision, different from classical eye photoreceptors used for cording dynamic images of vision. The cited literature provides evidence that the depolarizing and hyperpolarizing photoresponses of simple photoreceptors play a role in the long-lasting potentiation of synaptic transmission of excitatory and inhibitory sensory inputs, and as well as in the potentiation and the suppression of the subsequent behavioral outputs. In short, we suggest that simple photoreceptors operate in the general potentiation of synaptic transmission and subsequent motor output; i.e., they perform a new photosensory function.

  2. Integrative taxonomy of the genus Onchidium Buchannan, 1800 (Mollusca, Gastropoda, Pulmonata, Onchidiidae

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    Benoît Dayrat

    2016-11-01

    Full Text Available In an effort to clarify the species diversity of onchidiid slugs, the taxonomy of the genus Onchidium Buchannan, 1800 is revised using an integrative approach. New, fresh specimens were collected in a large number of places, including type localities. The genus Onchidium is redefined here as a clade including only three species which are strongly supported by both morphological and molecular data. All three species were already named: the type species O. typhae Buchannan, 1800, O. stuxbergi (Westerlund, 1883, and O. reevesii (J.E. Gray, 1850. With the exception of a re-description of O. typhae published in 1869, all three species are re-described here for the first time. First-hand observations on the color variation of live animals in their natural habitat are provided. The anatomy of each species is described. Important nomenclatural issues are addressed. In particular, Labella Starobogatov, 1976 is regarded as a junior synonym of Onchidium and Labella ajuthiae (Labbé, 1935 and O. nigrum (Plate, 1893 are regarded as junior synonyms of O. stuxbergi. The nomenclatural status of several other species names is discussed as well. Many new records are provided across South-East Asia and precise ranges of geographic distributions are provided for the genus Onchidium and its three species. Distinctive features that help distinguish the genus Onchidium from other onchidiids are provided, as well as an identification key for the three species.

  3. Acquired phototrophy through retention of functional chloroplasts increases growth efficiency of the sea slug Elysia viridis.

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    Finn A Baumgartner

    Full Text Available Photosynthesis is a fundamental process sustaining heterotrophic organisms at all trophic levels. Some mixotrophs can retain functional chloroplasts from food (kleptoplasty, and it is hypothesized that carbon acquired through kleptoplasty may enhance trophic energy transfer through increased host growth efficiency. Sacoglossan sea slugs are the only known metazoans capable of kleptoplasty, but the relative fitness contributions of heterotrophy through grazing, and phototrophy via kleptoplasts, are not well understood. Fitness benefits (i.e. increased survival or growth of kleptoplasty in sacoglossans are commonly studied in ecologically unrealistic conditions under extended periods of complete darkness and/or starvation. We compared the growth efficiency of the sacoglossan Elysia viridis with access to algal diets providing kleptoplasts of differing functionality under ecologically relevant light conditions. Individuals fed Codium fragile, which provide highly functional kleptoplasts, nearly doubled their growth efficiency under high compared to low light. In contrast, individuals fed Cladophora rupestris, which provided kleptoplasts of limited functionality, showed no difference in growth efficiency between light treatments. Slugs feeding on Codium, but not on Cladophora, showed higher relative electron transport rates (rETR in high compared to low light. Furthermore, there were no differences in the consumption rates of the slugs between different light treatments, and only small differences in nutritional traits of algal diets, indicating that the increased growth efficiency of E. viridis feeding on Codium was due to retention of functional kleptoplasts. Our results show that functional kleptoplasts from Codium can provide sacoglossan sea slugs with fitness advantages through photosynthesis.

  4. Kleptoplasts photoacclimation state modulates the photobehaviour of the solar-powered sea slug Elysia viridis.

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    Cartaxana, Paulo; Morelli, Luca; Quintaneiro, Carla; Calado, Gonçalo; Calado, Ricardo; Cruz, Sónia

    2018-04-30

    Some sacoglossan sea slugs incorporate intracellular functional algal chloroplasts (kleptoplasty) for periods ranging from a few days to several months. Whether this association modulates the photobehaviour of solar-powered sea slugs is unknown. In this study, the long-term retention species Elysia viridis showed avoidance of dark independently of light acclimation state. On the contrary, Placida dendritica , which shows non-functional retention of kleptoplasts, showed no preference over dark, low or high light. High light acclimated (HL ac ) E. viridis showed a higher preference for high light than low light acclimated (LL ac ) conspecifics. The position of the lateral folds (parapodia) was modulated by irradiance, with increasing light levels leading to a closure of parapodia and protection of kleptoplasts from high light exposure. Furthermore, closure of parapodia occurred at higher irradiances in HL ac E. viridis Our results strongly indicate that kleptoplasts photoacclimation state modulates the photobehaviour of the solar-powered sea slug E. viridis . © 2018. Published by The Company of Biologists Ltd.

  5. Antimicrobial Potential of Bacteria Associated with Marine Sea Slugs from North Sulawesi, Indonesia

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    Nils Böhringer

    2017-06-01

    Full Text Available Nudibranchia, marine soft-bodied organisms, developed, due to the absence of a protective shell, different strategies to protect themselves against putative predators and fouling organisms. One strategy is to use chemical weapons to distract predators, as well as pathogenic microorganisms. Hence, these gastropods take advantage of the incorporation of chemical molecules. Thereby the original source of these natural products varies; it might be the food source, de novo synthesis from the sea slug, or biosynthesis by associated bacteria. These bioactive molecules applied by the slugs can become important drug leads for future medicinal drugs. To test the potential of the associated bacteria, the latter were isolated from their hosts, brought into culture and extracts were prepared and tested for antimicrobial activities. From 49 isolated bacterial strains 35 showed antibiotic activity. The most promising extracts were chosen for further testing against relevant pathogens. In that way three strains showing activity against methicillin resistant Staphylococcus aureus and one strain with activity against enterohemorrhagic Escherichia coli, respectively, were identified. The obtained results indicate that the sea slug associated microbiome is a promising source for bacterial strains, which hold the potential for the biotechnological production of antibiotics.

  6. Plastid-bearing sea slugs fix CO2 in the light but do not require photosynthesis to survive

    NARCIS (Netherlands)

    Christa, Gregor; Zimorski, Verena; Woehle, Christian; Tielens, Aloysius G M; Wägele, Heike; Martin, William F; Gould, Sven B

    2014-01-01

    Several sacoglossan sea slugs (Plakobranchoidea) feed upon plastids of large unicellular algae. Four species--called long-term retention (LtR) species--are known to sequester ingested plastids within specialized cells of the digestive gland. There, the stolen plastids (kleptoplasts) remain

  7. Sea Slugs, Subliminal Pictures, and Vegetative State Patients: Boundaries of Consciousness in Classical Conditioning

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    Bekinschtein, Tristan A.; Peeters, Moos; Shalom, Diego; Sigman, Mariano

    2011-01-01

    Classical (trace) conditioning is a specific variant of associative learning in which a neutral stimulus leads to the subsequent prediction of an emotionally charged or noxious stimulus after a temporal gap. When conditioning is concurrent with a distraction task, only participants who can report the relationship (the contingency) between stimuli explicitly show associative learning. This suggests that consciousness is a prerequisite for trace conditioning. We review and question three main controversies concerning this view. Firstly, virtually all animals, even invertebrate sea slugs, show this type of learning; secondly, unconsciously perceived stimuli may elicit trace conditioning; and thirdly, some vegetative state patients show trace learning. We discuss and analyze these seemingly contradictory arguments to find the theoretical boundaries of consciousness in classical conditioning. We conclude that trace conditioning remains one of the best measures to test conscious processing in the absence of explicit reports. PMID:22164148

  8. Sea slugs, subliminal pictures and vegetative state patients: Boundaries of consciousness in classical conditioning.

    Directory of Open Access Journals (Sweden)

    Tristan A Bekinschtein

    2011-12-01

    Full Text Available Classical (trace conditioning is a specific variant of associative learning in which a neutral stimulus leads to the subsequent prediction of an emotionally charged or noxious stimulus after a temporal gap. When conditioning is concurrent with a distraction task, only participants who can report the relationship (the contingency between stimuli explicitly show associative learning. This suggests that consciousness is a prerequisite for trace conditioning. We review and question three main controversies concerning this view. Firstly, virtually all animals, even invertebrate sea slugs, show this type of learning; secondly, unconsciously perceived stimuli may elicit trace conditioning; and thirdly, some vegetative state patients show trace learning. We discuss and analyze these seemingly contradictory arguments to find the theoretical boundaries of consciousness in classical conditioning. We conclude that trace conditioning remains one of the best measures to test conscious processing in the absence of explicit reports.

  9. The Unique Propulsive Wake Pattern of the Swimming Sea Slug Aplysia

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    Zhou, Zhuoyu; Mittal, Rajat

    2017-11-01

    The Aplysia, also sometimes referred to as the `Sea Hare,' is a sea slug that swims elegantly using large-amplitude flapping of its mantle. The Sea Hare has become a very valuable laboratory animal for investigation into nervous systems and brain behavior due to its simple neural system with large neurons and axons. Recently, attempts have also been made to develop biohybrid robots with both organic actuation and organic motor-pattern control inspired by the locomotion of Aplysia. While extensive works have been done to investigate this animal's neurobiology, relatively little is known about its propulsive mechanisms and swimming energetics. In this study, incompressible flow simulations with a simple kinematical model are used to gain insights into vortex dynamics, thrust generation and energetics of locomotion. The effect of mantle kinematics on the propulsive performance is examined, and simulations indicate a unique vortex wake pattern that is responsible for thrust generation. The research is supported by NSF Grant PLR-1246317 and NSF XSEDE Grant TG-CTS100002.

  10. Barcoding against a paradox? Combined molecular species delineations reveal multiple cryptic lineages in elusive meiofaunal sea slugs

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    Jörger Katharina M

    2012-12-01

    Full Text Available Abstract Background Many marine meiofaunal species are reported to have wide distributions, which creates a paradox considering their hypothesized low dispersal abilities. Correlated with this paradox is an especially high taxonomic deficit for meiofauna, partly related to a lower taxonomic effort and partly to a high number of putative cryptic species. Molecular-based species delineation and barcoding approaches have been advocated for meiofaunal biodiversity assessments to speed up description processes and uncover cryptic lineages. However, these approaches show sensitivity to sampling coverage (taxonomic and geographic and the success rate has never been explored on mesopsammic Mollusca. Results We collected the meiofaunal sea-slug Pontohedyle (Acochlidia, Heterobranchia from 28 localities worldwide. With a traditional morphological approach, all specimens fall into two morphospecies. However, with a multi-marker genetic approach, we reveal multiple lineages that are reciprocally monophyletic on single and concatenated gene trees in phylogenetic analyses. These lineages are largely concordant with geographical and oceanographic parameters, leading to our primary species hypothesis (PSH. In parallel, we apply four independent methods of molecular based species delineation: General Mixed Yule Coalescent model (GMYC, statistical parsimony, Bayesian Species Delineation (BPP and Automatic Barcode Gap Discovery (ABGD. The secondary species hypothesis (SSH is gained by relying only on uncontradicted results of the different approaches (‘minimum consensus approach’, resulting in the discovery of a radiation of (at least 12 mainly cryptic species, 9 of them new to science, some sympatric and some allopatric with respect to ocean boundaries. However, the meiofaunal paradox still persists in some Pontohedyle species identified here with wide coastal and trans-archipelago distributions. Conclusions Our study confirms extensive, morphologically

  11. Chloroplast genes are expressed during intracellular symbiotic association of Vaucheria litorea plastids with the sea slug Elysia chlorotica.

    OpenAIRE

    Mujer, C V; Andrews, D L; Manhart, J R; Pierce, S K; Rumpho, M E

    1996-01-01

    The marine slug Elysia chlorotica (Gould) forms an intracellular symbiosis with photosynthetically active chloroplasts from the chromophytic alga Vaucheria litorea (C. Agardh). This symbiotic association was characterized over a period of 8 months during which E. chlorotica was deprived of V. litorea but provided with light and CO2. The fine structure of the symbiotic chloroplasts remained intact in E. chlorotica even after 8 months of starvation as revealed by electron microscopy. Southern b...

  12. Initiation of slug flow

    Energy Technology Data Exchange (ETDEWEB)

    Hanratty, T.J.; Woods, B.D. [Univ. of Illinois, Urbana, IL (United States)

    1995-12-31

    The initiation of slug flow in a horizontal pipe can be predicted either by considering the stability of a slug or by considering the stability of a stratified flow. Measurements of the shedding rate of slugs are used to define necessary conditions for the existence of a slug. Recent results show that slugs develop from an unstable stratified flow through the evolution of small wavelength waves into large wavelength waves that have the possibility of growing to form a slug. The mechanism appears to be quite different for fluids with viscosities close to water than for fluids with large viscosities (20 centipoise).

  13. Chloroplast genes are expressed during intracellular symbiotic association of Vaucheria litorea plastids with the sea slug Elysia chlorotica.

    Science.gov (United States)

    Mujer, C V; Andrews, D L; Manhart, J R; Pierce, S K; Rumpho, M E

    1996-10-29

    The marine slug Elysia chlorotica (Gould) forms an intracellular symbiosis with photosynthetically active chloroplasts from the chromophytic alga Vaucheria litorea (C. Agardh). This symbiotic association was characterized over a period of 8 months during which E. chlorotica was deprived of V. litorea but provided with light and CO2. The fine structure of the symbiotic chloroplasts remained intact in E. chlorotica even after 8 months of starvation as revealed by electron microscopy. Southern blot analysis of total DNA from E. chlorotica indicated that algal genes, i.e., rbcL, rbcS, psaB, psbA, and 16S rRNA are present in the animal. These genes are typically localized to the plastid genome in higher plants and algae except rbcS, which is nuclear-encoded in higher plants and green (chlorophyll a/b) algae. Our analysis suggests, however, that similar to the few other chromophytes (chlorophyll a/c) examined, rbcS is chloroplast encoded in V. litorea. Levels of psbA transcripts remained constant in E. chlorotica starved for 2 and 3 months and then gradually declined over the next 5 months corresponding with senescence of the animal in culture and in nature. The RNA synthesis inhibitor 6-methylpurine reduced the accumulation of psbA transcripts confirming active transcription. In contrast to psbA, levels of 16S rRNA transcripts remained constant throughout the starvation period. The levels of the photosystem II proteins, D1 and CP43, were high at 2 and 4 months of starvation and remained constant at a lower steady-state level after 6 months. In contrast, D2 protein levels, although high at 2 and 4 months, were very low at all other periods of starvation. At 8 months, de novo synthesis of several thylakoid membrane-enriched proteins, including D1, still occurred. To our knowledge, these results represent the first molecular evidence for active transcription and translation of algal chloroplast genes in an animal host and are discussed in relation to the endosymbiotic

  14. Prematurely terminated slug tests

    International Nuclear Information System (INIS)

    Karasaki, K.

    1990-07-01

    A solution of the well response to a prematurely terminated slug test (PTST) is presented. The advantages of a PTST over conventional slug tests are discussed. A systematized procedure of a PTST is proposed, where a slug test is terminated in the midpoint of the flow point, and the subsequent shut-in data is recorded and analyzed. This method requires a downhole shut-in device and a pressure transducer, which is no more than the conventional deep-well slug testing. As opposed to slug tests, which are ineffective when a skin is present, more accurate estimate of formation permeability can be made using a PTST. Premature termination also shortens the test duration considerably. Because in most cases no more information is gained by completing a slug test to the end, the author recommends that conventional slug tests be replaced by the premature termination technique. This study is part of an investigation of the feasibility of geologic isolation of nuclear wastes being carried out by the US Department of Energy and the National Cooperative for the Storage of Radioactive Waste of Switzerland

  15. The dynamics of slug trains in volcanic conduits: Evidence for expansion driven slug coalescence

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    Pering, T. D.; McGonigle, A. J. S.; James, M. R.; Capponi, A.; Lane, S. J.; Tamburello, G.; Aiuppa, A.

    2017-12-01

    Strombolian volcanism is a ubiquitous form of activity, driven by the ascent and bursting of bubbles of slug morphology. Whilst considerable attention has been devoted to understanding the behaviour of individual slugs in this regime, relatively little is known about how inter-slug interactions modify flow conditions. Recently, we reported on high temporal frequency strombolian activity on Etna, in which the larger erupted slug masses were followed by longer intervals before the following explosion than the smaller bursts (Pering et al., 2015). We hypothesised that this behaviour arose from the coalescence of ascending slugs causing a prolonged lag before arrival of the next distinct bubble. Here we consider the potential importance of inter-slug interactions for the dynamics of strombolian volcanism, by reporting on the first study into the behaviour of trains of ascending gas slugs, scaled to the expansion rates in volcanic conduits. This laboratory analogue study illustrates that slugs in trains rise faster than individual slugs, and can be associated with aspects of co-current flow. The work also highlights that coalescence and inter-slug interactions play an important role in modulating slug train behaviour. We also report, for the first time, on slug coalescence driven by vertical expansion of the trailing slug, a process which can occur, even where the leading slug base ascent velocity is greater than that of the trailing slug.

  16. OIL SLUGS FOR PRODUCTION OF PISTON RING

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    V. F. Bevza

    2008-01-01

    Full Text Available The developed technological process of continuously cyclic casting by frosting allows to receive high-quality hollow cylindrical slugs of cast iron for production of critical parts. 

  17. Modeling of two-phase slug flow

    International Nuclear Information System (INIS)

    Fabre, J.; Line, A.

    1992-01-01

    When gas and liquid flow in a pipe, over a range of flow rates, a flow pattern results in which sequences of long bubbles, almost filling the pipe cross section, are successively followed by liquid slugs that may contain small bubbles. This flow pattern, usually called slug flow, is encountered in numerous practical situations, such as in the production of hydrocarbons in wells and their transportation in pipelines; the production of steam and water in geothermal power plants; the boiling and condensation in liquid-vapor systems of thermal power plants; emergency core cooling of nuclear reactors; heat and mass transfer between gas and liquid in chemical reactors. This paper provides a review of two phase slug flow modeling

  18. Multiphase flow measurement in the slug regime using ultrasonic measurement techniques and slug closure model

    OpenAIRE

    Al-lababidi , Salem

    2006-01-01

    Multiphase flow in the oil and gas industry covers a wide range of flows. Thus, over the last decade, the investigation, development and use of multiphase flow metering system have been a major focus for the industry worldwide. However, these meters do not perform well in slug flow conditions. The present work involves experimental investigations of multiphase flow measurement under slug flow conditions. A two-phase gas/liquid facility was designed and constructed at Cranfie...

  19. SlugIn 1.0: A Free Tool for Automated Slug Test Analysis.

    Science.gov (United States)

    Martos-Rosillo, Sergio; Guardiola-Albert, Carolina; Padilla Benítez, Alberto; Delgado Pastor, Joaquín; Azcón González, Antonio; Durán Valsero, Juan José

    2018-05-01

    The correct characterization of aquifer parameters is essential for water-supply and water-quality investigations. Slug tests are widely used for these purposes. While free software is available to interpret slug tests, some codes are not user-friendly, or do not include a wide range of methods to interpret the results, or do not include automatic, inverse solutions to the test data. The private sector has also generated several good programs to interpret slug test data, but they are not free of charge. The computer program SlugIn 1.0 is available online for free download, and is demonstrated to aid in the analysis of slug tests to estimate hydraulic parameters. The program provides an easy-to-use Graphical User Interface. SlugIn 1.0 incorporates automated parameter estimation and facilitates the visualization of several interpretations of the same test. It incorporates solutions for confined and unconfined aquifers, partially penetrating wells, skin effects, shape factor, anisotropy, high hydraulic conductivity formations and the Mace test for large-diameter wells. It is available in English and Spanish and can be downloaded from the web site of the Geological Survey of Spain. Two field examples are presented to illustrate how the software operates. © 2018, National Ground Water Association.

  20. Survey of nematodes associated with terrestrial slugs in Norway.

    Science.gov (United States)

    Ross, J L; Ivanova, E S; Hatteland, B A; Brurberg, M B; Haukeland, S

    2016-09-01

    A survey of nematodes associated with terrestrial slugs was conducted for the first time in Norway. A total of 611 terrestrial slugs were collected from 32 sample sites. Slugs were identified by means of morphological examination, dissection of genitalia and molecular analysis using mitochondrial DNA. Twelve slug species were identified, representing four different slug families. Internal nematodes were identified by means of morphological analysis and the sequencing of the 18S rRNA gene. Of the sample sites studied, 62.5% were found to be positive for nematode parasites, with 18.7% of all slugs discovered being infected. Five nematode species were identified in this study: Alloionema appendiculatum, Agfa flexilis, Angiostoma limacis, Angiostoma sp. and Phasmarhabditis hermaphrodita. Of these species, only one nematode was previously undescribed (Angiostoma sp.). This is the first record of the presence of A. appendiculatum, A. flexilis and A. limacis in Norway.

  1. A nematode that can manipulate the behaviour of slugs.

    Science.gov (United States)

    Morris, Alex; Green, Michael; Martin, Hayley; Crossland, Katie; Swaney, William T; Williamson, Sally M; Rae, Robbie

    2018-06-01

    The ability of parasites to manipulate the behaviour of their hosts has evolved multiple times, and has a clear fitness benefit to the parasite in terms of facilitating growth, reproduction and transfer to suitable hosts. The mechanisms by which these behavioural changes are induced are poorly understood, but in many cases parasite manipulation of serotonergic signalling in the host brain is implicated. Here we report that Phasmarhabditis hermaphrodita, a parasite of terrestrial gastropod molluscs, can alter the behaviour of slugs. Uninfected slugs (Deroceras panormitanum, Arion subfuscus and Arion hortensis) avoid areas where P. hermaphrodita is present, but slugs infected with P. hermaphrodita are more likely to be found where the nematodes are present. This ability is specific to P. hermaphrodita and other nematodes (Steinernema carpocapsae and Heterorhabditis bacteriophora) do not induce this behavioural change. To investigate how P. hermaphrodita changes slug behaviour we exposed slugs to fluoxetine (a selective serotonin reuptake inhibitor) and cyproheptadine (a serotonin receptor antagonist). Uninfected slugs fed fluoxetine no longer avoided areas where P. hermaphrodita was present; and conversely, infected slugs fed cyproheptadine showed no increased attraction to areas with nematodes. These findings suggest that a possible mechanism by which P. hermaphrodita is able to manipulate parasite avoidance behaviour in host slugs is by manipulating serotonergic signalling in the brain, and that increased serotonin levels are potentially associated with a reduction in parasite avoidance. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. An analytical study of slug impact phenomena

    International Nuclear Information System (INIS)

    Smith, B.L.

    1983-05-01

    Following a HCDA the roof of a fast reactor may be threatened by coolant impact. This article aims to develop at a fundamental level, understanding of the impact process and assess the relevance and magnitude of fluid-structure interaction effects. Reference is made to four 1/30th scale experiments, set up to verify the ideas developed in this work, and to provide quality data for code validation purposes. The impact of a one-dimensional liquid slug on a solid slab is investigated using a simplified form of the Rankine-Hugoniot shock equations derived under the joint assumptions of slight compressibility and small Mach number. Initially the roof slab is considered to be freely supported and of finite thickness. A detailed picture of the shock and expansion wave propagations is built up from the basic equations including the effects of wave reflections at boundaries and wave-wave interactions. Particular attention is paid to the impulse transfer mechanism from the slug as this controls the roof slab acceleration. Bulk fluid cavitation effects are noted. Roof flexural response is then taken into account, together with the effects of the hold-down constraints. It is seen that even very minor structural responses can result in significant mitigation of the impulse loading. Guidelines for the application of the work to HCDA analysis in pool reactor geometries are presented. (Auth.)

  3. Slug flooding in air-water countercurrent vertical flow

    International Nuclear Information System (INIS)

    Lee, Jae Young; Raman, Roger; Chang, Jen-Shih

    2000-01-01

    This paper is to study slug flooding in the vertical air-water countercurrent flow loop with a porous liquid injector in the upper plenum. More water penetration into the bottom plenum in slug flooding is observed than the annular flooding because the flow regime changes from the slug flow regime or periodic slug/annular flow regime to annular flow regime due to the hysteresis between the onset of flooding and the bridging film. Experiments were made tubes of 0.995 cm, 2.07 cm, and 5.08 cm in diameter. A mechanistic model for the slug flooding with the solitary wave whose height is four time of the mean film thickness is developed to produce relations of the critical liquid flow rate and the mean film thickness. After fitting the critical liquid flow rate with the experimental data as a function of the Bond number, the gas flow rate for the slug flooding is obtained by substituting the critical liquid flow rate to the annular flooding criteria. The present experimental data evaluate the slug flooding condition developed here by substituting the correlations for mean film thickness models in the literature. The best prediction was made by the correlation for the mean film thickness of the present study which is same as Feind's correlation multiplied by 1.35. (author)

  4. Local studies in horizontal gas-liquid slug flow

    International Nuclear Information System (INIS)

    Sharma, S.; Lewis, S.; Kojasoy, G.

    1998-01-01

    The local axial velocity profile development in a horizontal air-water slug flow-pattern was experimentally investigated by simultaneously using two hot-film anemometers. One of the probes was exclusively used as phase identifier while the other probe was traversed for local velocity measurements. It was shown that the velocity rapidly develops into asymmetric but nearly fully-developed profiles within the liquid slugs whereas the velocity never develops into quasi-fully-developed profiles within the liquid layer underneath passing gas slugs. Transient nature of velocity at a given location was demonstrated. (author)

  5. Slug flow in horizontal pipes with transpiration at the wall

    Science.gov (United States)

    Loureiro, J. B. R.; Silva Freire, A. P.

    2011-12-01

    The present work investigates the behaviour of slug flows in horizontal pipes with a permeable wall. Measurements of pressure drop and of local velocity are given for nine different flow conditions. The liquid phase velocity was measured with laser Doppler anemometry. Single-phase data are compared with the results of other authors. The influence of flow transpiration and of roughness on the features of slug flows is shown to be pronounced. A Shadow Sizer system coupled with Particle Image Velocimetry is used to account for the properties of the slug cell.

  6. Slug flow in horizontal pipes with transpiration at the wall

    Energy Technology Data Exchange (ETDEWEB)

    Loureiro, J B R; Freire, A P Silva, E-mail: jbrloureiro@mecanica.ufrj.br [Mechanical Engineering Program, Federal University of Rio de Janeiro (COPPE/UFRJ), C.P. 68503, 21.941-972, Rio de Janeiro, RJ (Brazil)

    2011-12-22

    The present work investigates the behaviour of slug flows in horizontal pipes with a permeable wall. Measurements of pressure drop and of local velocity are given for nine different flow conditions. The liquid phase velocity was measured with laser Doppler anemometry. Single-phase data are compared with the results of other authors. The influence of flow transpiration and of roughness on the features of slug flows is shown to be pronounced. A Shadow Sizer system coupled with Particle Image Velocimetry is used to account for the properties of the slug cell.

  7. Slug flow in horizontal pipes with transpiration at the wall

    International Nuclear Information System (INIS)

    Loureiro, J B R; Freire, A P Silva

    2011-01-01

    The present work investigates the behaviour of slug flows in horizontal pipes with a permeable wall. Measurements of pressure drop and of local velocity are given for nine different flow conditions. The liquid phase velocity was measured with laser Doppler anemometry. Single-phase data are compared with the results of other authors. The influence of flow transpiration and of roughness on the features of slug flows is shown to be pronounced. A Shadow Sizer system coupled with Particle Image Velocimetry is used to account for the properties of the slug cell.

  8. Slug control system; Sistema de controle de golfadas

    Energy Technology Data Exchange (ETDEWEB)

    Borges Filho, Alvaro de Miranda; Meira, Marco Antonio Alves de; Vaz, Celio Eduardo Martins [PETROBRAS, Macae, RJ (Brazil). Unidade de Negocios da Bacia de Campos

    2004-07-01

    Due to the characteristics of flow, gas can separate from oil in the pipelines and risers that link subsea manifolds to production offshore platforms, forming liquid and gas slugs in the production separator. Liquid slugs can cause overflow in the separators. Gas slugs can cause burning in the flare due to the limitation in the turbo-compressors acceleration. In both cases the consequences are loss of production or shut-downs. This paper presents a Slug Control System designed to attenuate severe gas and liquid flow variations. The system consist of a control valve installed in the separator inlet, transmitters, a controller, control algorithm and a monitoring station. This system is operating since October 2003 in a production offshore platform, in Campus Basin, Brazil, with excellent results, reducing the gas burning in 45% without oil production loss. (author)

  9. Bed diameter effects and incipient slugging in gas fluidized beds

    International Nuclear Information System (INIS)

    Agarwal, P.K.

    1986-01-01

    The coalescence and growth of bubble swarms formed at the distributor of a fluidized bed gives rise to lateral as well as vertical distributions of bubble properties. However, existing models employ average bubble properties obtained largely from semi-empirical considerations. In a recent Paper, the author developed a bubble growth model based on a population balance approach. Analytical expressions were derived for the bubble characteristic distributions and averages. However, the model, developed for unconstrained growth, did not take into account the effect of the bed diameter and the possibility of slugging. In this Paper, the model is extended to take these aspects into account. A slugging criterion is also developed which is expected to be valid for the regime where incipient slugging depends on the bed height as well as the region where bed height does not significantly affect minimum slugging conditions

  10. SLUG (SNAI2) deletions in patients with Waardenburg disease.

    Science.gov (United States)

    Sánchez-Martín, Manuel; Rodríguez-García, Arancha; Pérez-Losada, Jesús; Sagrera, Ana; Read, Andrew P; Sánchez-García, Isidro

    2002-12-01

    Waardenburg syndrome (WS; deafness with pigmentary abnormalities) is a congenital disorder caused by defective function of the embryonic neural crest. Depending on additional symptoms, WS is classified into four types: WS1, WS2, WS3 and WS4. WS1 and WS3 are caused by mutations in PAX3, whereas WS2 is heterogenous, being caused by mutations in the microphthalmia (MITF) gene in some but not all affected families. The identification of Slugh, a zinc-finger transcription factor expressed in migratory neural crest cells, as the gene responsible for pigmentary disturbances in mice prompted us to analyse the role of its human homologue SLUG in neural crest defects. Here we show that two unrelated patients with WS2 have homozygous deletions in SLUG which result in absence of the SLUG product. We further show that Mitf is present in Slug-deficient cells and transactivates the SLUG promoter, and that Slugh and Kit genetically interact in vivo. Our findings further define the locus heterogeneity of WS2 and point to an essential role of SLUG in the development of neural crest-derived human cell lineages: its absence causes the auditory-pigmentary symptoms in at least some individuals with WS2.

  11. Cellular properties of slug flow in vertical co-current gas-liquid flow: slug-churn transition

    International Nuclear Information System (INIS)

    Lusseyran, Francois

    1990-01-01

    This research thesis reports the study and description of the structure of a slug flow regime in a co-current vertical cylindrical duct, and the characterization and prediction of its transition towards a slug-churn (de-structured) regime. Flow physical mechanisms highlighted by the measurement of two important dynamics variables (wall friction and thickness of liquid films) are related to hypotheses of cellular models. The author first proposes an overview of slug flow regimes: theoretical steady and one-dimensional analysis, mass assessment equations of cellular models, application to the assessment of the flow rate and of the thickness of the film surrounding the gas slug. In the second part, the author addresses the slug flow regime transition towards the slug-churn regime: assessment of the evolution of flow dynamic properties, use of average wall friction analysis to obtain a relevant transition criterion. The third part presents experimental conditions, and measurement methods: conductometry for thickness measurement, polarography for wall friction measurement, and gas phase detection by using an optic barrier or optic fibres [fr

  12. Determination of C0-60 in Cobalt Slugs and Slabs and Radionuclides in Curium Sampler Slugs L-Reactor Disassembly Basin

    International Nuclear Information System (INIS)

    Casella, V.R.

    2004-01-01

    Co-60 was historically produced in the SRS reactors. Cobalt slugs were irradiated in the early 1970s. Post-production, remaining cobalt slugs (including slab form) were consolidated for storage. There are approximately nine hundred cobalt slugs currently stored awaiting final disposition. These slugs had historically incomplete documentation for activity rates; therefore, assaying was required in order to determine their activity levels. Since the gamma dose rate from these slugs is extremely high, the most cost effective way to shield a source of this magnitude from personnel and the radiation detector was to use the basin water in which the slugs are stored as the shield. A sodium iodide gamma detector was placed above a specially designed air collimator assembly, so that slug was at least eight feet from the detector and was shielded by the basin water. Using a sodium iodide detector and multichannel analyzer system and an underwater collimator assembly, Co-60 concentrations we re determined for Disassembly Basin cobalt slugs and slabs and 18 curium sampler slugs. The total activity of all of the assayed slugs summed to 31,783 curies. From the Co-60 concentrations of the curium sampler slugs, the irradiation flux was determined for the known irradiation time. The amounts of Pu-238, 239, 240, 241, 242; Am-241, 243; and Cm-242, 244 produced were then obtained based on the original amount of Pu-239 irradiated

  13. Severe Slugging in Air-Water Hybrid Riser System

    Directory of Open Access Journals (Sweden)

    Jing Gong

    2014-11-01

    Full Text Available In the subsea pipeline gathering system, severe slugging flow is prone to occur. Severe slugging flow brings major threat to production and flow assurance in oil and gas industry due to periodical pressure oscillation and large liquid volume. Currently many researchers pay much more attention on L-shaped riser, catenaries, and S-shaped riser; little research has been made on hybrid riser, which is applied in the Africa West and Gulf of Mexico oil fields. Flow characteristics simulation for hybrid riser is made in this paper, using the one-dimensional and quasi-equilibrium model to simulate not only the riser-base pressure, severe slugging period, and the liquid slug length of the whole system but also base-pressure in the flexible pipe section. The calculated results match well with the experiment data. Besides, the influence of flexible pipe to the severe slugging characteristics of hybrid riser system is analyzed, which are significant for the determination of riser structure.

  14. An invasive slug exploits an ant-seed dispersal mutualism.

    Science.gov (United States)

    Meadley Dunphy, Shannon A; Prior, Kirsten M; Frederickson, Megan E

    2016-05-01

    Plant-animal mutualisms, such as seed dispersal, are often vulnerable to disruption by invasive species. Here, we show for the first time how a non-ant invasive species negatively affects seed dispersal by ants. We examined the effects of several animal species that co-occur in a temperate deciduous forest-including native and invasive seed-dispersing ants (Aphaenogaster rudis and Myrmica rubra, respectively), an invasive slug (Arion subfuscus), and native rodents-on a native myrmecochorous plant, Asarum canadense. We experimentally manipulated ant, slug, and rodent access to seed depots and measured seed removal. We also video-recorded depots to determine which other taxa interact with seeds. We found that A. rudis was the main disperser of seeds and that A. subfuscus consumed elaiosomes without dispersing seeds. Rodent visitation was rare, and rodent exclusion had no significant effect on seed or elaiosome removal. We then used data obtained from laboratory and field mesocosm experiments to determine how elaiosome robbing by A. subfuscus affects seed dispersal by A. rudis and M. rubra. We found that elaiosome robbing by slugs reduced seed dispersal by ants, especially in mesocosms with A. rudis, which picks up seeds more slowly than M. rubra. Taken together, our results show that elaiosome robbing by an invasive slug reduces seed dispersal by ants, suggesting that invasive slugs can have profound negative effects on seed dispersal mutualisms.

  15. A model for cell type localization in the migrating slug of ...

    Indian Academy of Sciences (India)

    PRAKASH

    . Localization of the three major cell types within the migrating slug stage is a dynamic process (Sternfeld 1992;. A model for cell type localization in the migrating slug of Dictyostelium discoideum based on differential chemotactic sensitivity to ...

  16. Chloroplast digestion and the development of functional kleptoplasty in juvenile Elysia timida (Risso, 1818 as compared to short-term and non-chloroplast-retaining sacoglossan slugs.

    Directory of Open Access Journals (Sweden)

    Elise Marie Jerschabek Laetz

    Full Text Available Sacoglossan sea slugs are the only metazoans known to perform functional kleptoplasty, the sequestration and retention of functional chloroplasts within their digestive gland cells. Remarkably, a few species with this ability can survive starvation periods of 3-12 months likely due to their stolen chloroplasts. There are no reports of kleptoplast transfer from mother slug to either eggs or juveniles, demonstrating that each animal must independently acquire its kleptoplasts and develop the ability to maintain them within its digestive gland. We present here an investigation into the development of functional kleptoplasty in a long-term kleptoplast retaining species, Elysia timida. Laboratory-reared juvenile slugs of different post-metamorphic ages were placed in starvation and compared to 5 known short-term retaining slug species and 5 non-retaining slug species. The subsequent results indicate that functional kleptoplasty is not performed by E. timida until after 15 days post-metamorphosis and that by 25 days, these animals outlive many of the short-term retention species. Digestive activity was also monitored using lysosomal abundance as an indicator, revealing different patterns in starving juveniles versus adults. Starved juveniles were reintroduced to food to determine any differences in digestive activity when starvation ends, resulting in an increase in the number of kleptoplasts, but no overall change in lysosomal activity. By revealing some of the changes that occur during early development in these animals, which begin as non-kleptoplast-retaining and grow into long-term retaining slugs, this investigation provides a basis for future inquiries into the origin and development of this remarkable ability.

  17. Slug to churn transition analysis using wire-mesh sensor

    Science.gov (United States)

    H. F. Velasco, P.; Ortiz-Vidal, L. E.; Rocha, D. M.; Rodriguez, O. M. H.

    2016-06-01

    A comparison between some theoretical slug to churn flow-pattern transition models and experimental data is performed. The flow-pattern database considers vertical upward air-water flow at standard temperature and pressure for 50 mm and 32 mm ID pipes. A briefly description of the models and its phenomenology is presented. In general, the performance of the transition models is poor. We found that new experimental studies describing objectively both stable and unstable slug flow-pattern are required. In this sense, the Wire Mesh Sensor (WMS) can assist to that aim. The potential of the WMS is outlined.

  18. Is a combination of different natural substances suitable for slug (Arion spp.) control?

    Energy Technology Data Exchange (ETDEWEB)

    Laznik, Ž.; Trdan, S.

    2016-11-01

    In a laboratory study we investigated the contact and barrier efficacy of different natural substances (wood ash, sawdust, hydrated lime, and diatomaceous earth) against slugs of the genus Arion, an important agricultural pest. Natural substances were tested individually and in combination with each other. The experiment was carried out in plastic petri dishes and in glass insectaria. Moistened tampons and fresh leaves of lettuce were placed into both experimental arenas. The slugs were starved for 48 hours prior to the experiment. Six categories of behaviour were identified for slugs in the presence of the natural substances: (1) slug survived the experiment, (2) slug died during the experiment, (3) slug crossed the barrier, (4) slug did not cross the barrier, (5) slug fed on the lettuce, and (6) slug did not feed on the lettuce. The effect of different treatments (natural substances) was significant. The results of our study have shown that hydrated lime had the best contact efficacy on slugs (the mortality of slugs was 100%), both individually and in combination with other substances. The treatments with hydrated lime also proved to be the most efficient barrier preventing slugs from feeding on lettuce. Hydrated lime shows great potential in Arion control in our investigation; however, further research is needed to investigate the practical value (how to avoid the problem when the substance becomes wet), safety and economics of hydrated lime used in this way. (Author)

  19. Internal Representation and Memory Formation of Odor Preference Based on Oscillatory Activities in a Terrestrial Slug

    Science.gov (United States)

    Sekiguchi, Tatsuhiko; Furudate, Hiroyuki; Kimura, Tetsuya

    2010-01-01

    The terrestrial slug "Limax" exhibits a highly developed ability to learn odors with a small nervous system. When a fluorescent dye, Lucifer Yellow (LY), is injected into the slug's body cavity after odor-taste associative conditioning, a group of neurons in the procerebral (PC) lobe, an olfactory center of the slug, is labeled by LY. We examined…

  20. SLUG promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis.

    Science.gov (United States)

    Uygur, Berna; Wu, Wen-Shu

    2011-11-10

    SLUG is a zinc-finger transcription factor of the Snail/Slug zinc-finger family that plays a role in migration and invasion of tumor cells. Mechanisms by which SLUG promotes migration and invasion in prostate cancers remain elusive. Expression level of CXCR4 and CXCL12 was examined by Western blot, RT-PCR, and qPCR analyses. Forced expression of SLUG was mediated by retroviruses, and SLUG and CXCL12 was downregulated by shRNAs-expressing lentiviruses. Migration and invasion of prostate cancer were measured by scratch-wound assay and invasion assay, respectively. We demonstrated that forced expression of SLUG elevated CXCR4 and CXCL12 expression in human prostate cancer cell lines PC3, DU145, 22RV1, and LNCaP; conversely, reduced expression of SLUG by shRNA downregulated CXCR4 and CXCL12 expression at RNA and protein levels in prostate cancer cells. Furthermore, ectopic expression of SLUG increased MMP9 expression and activity in PC3, 22RV1, and DU-145 cells, and SLUG knockdown by shRNA downregulated MMP9 expression. We showed that CXCL12 is required for SLUG-mediated MMP9 expression in prostate cancer cells. Moreover, we found that migration and invasion of prostate cancer cells was increased by ectopic expression of SLUG and decreased by SLUG knockdown. Notably, knockdown of CXCL12 by shRNA impaired SLUG-mediated migration and invasion in prostate cancer cells. Lastly, our data suggest that CXCL12 and SLUG regulate migration and invasion of prostate cancer cells independent of cell growth. We provide the first compelling evidence that upregulation of autocrine CXCL12 is a major mechanism underlying SLUG-mediated migration and invasion of prostate cancer cells. Our findings suggest that CXCL12 is a therapeutic target for prostate cancer metastasis.

  1. SNAI2/Slug promotes growth and invasion in human gliomas

    International Nuclear Information System (INIS)

    Yang, Hong Wei; Menon, Lata G; Black, Peter M; Carroll, Rona S; Johnson, Mark D

    2010-01-01

    Numerous factors that contribute to malignant glioma invasion have been identified, but the upstream genes coordinating this process are poorly known. To identify genes controlling glioma invasion, we used genome-wide mRNA expression profiles of primary human glioblastomas to develop an expression-based rank ordering of 30 transcription factors that have previously been implicated in the regulation of invasion and metastasis in cancer. Using this approach, we identified the oncogenic transcriptional repressor, SNAI2/Slug, among the upper tenth percentile of invasion-related transcription factors overexpressed in glioblastomas. SNAI2 mRNA expression correlated with histologic grade and invasive phenotype in primary human glioma specimens, and was induced by EGF receptor activation in human glioblastoma cells. Overexpression of SNAI2/Slug increased glioblastoma cell proliferation and invasion in vitro and promoted angiogenesis and glioblastoma growth in vivo. Importantly, knockdown of endogenous SNAI2/Slug in glioblastoma cells decreased invasion and increased survival in a mouse intracranial human glioblastoma transplantation model. This genome-scale approach has thus identified SNAI2/Slug as a regulator of growth and invasion in human gliomas

  2. Individual based model of slug population and spatial dynamics

    NARCIS (Netherlands)

    Choi, Y.H.; Bohan, D.A.; Potting, R.P.J.; Semenov, M.A.; Glen, D.M.

    2006-01-01

    The slug, Deroceras reticulatum, is one of the most important pests of agricultural and horticultural crops in UK and Europe. In this paper, a spatially explicit individual based model (IbM) is developed to study the dynamics of a population of D. reticulatum. The IbM establishes a virtual field

  3. Modeling the scooping phenomenon for the heat transfer in liquid–gas horizontal slug flows

    International Nuclear Information System (INIS)

    Bassani, Carlos L.; Pereira, Fernando H.G.; Barbuto, Fausto A.A.; Morales, Rigoberto E.M.

    2016-01-01

    Highlights: • A low computational tool for heat transfer prediction on slug flows is presented. • The scooping phenomenon is modeled on a stationary approach. • The scooping phenomenon improved in 8% the heat transfer results. - Abstract: The heat transfer between the deep sea waters and the oil and gas mixtures flowing through production lines is a common situation in the petroleum industry. The optimum prediction of the liquid–gas flow parameters along those lines, when the intermittent flow pattern known as slug flow is dominant, has extreme importance in facilities' design. The mixture temperature drop caused by the colder sea waters, which can be regarded as an infinite medium with constant temperature, directly affects physical properties of the fluids such as the viscosity and specific mass. Gas expansion may also occur due to pressure and temperature gradients, thus changing the flow hydrodynamics. Finally, the temperature gradient affects the thermodynamic equilibrium between the phases, favoring wax deposition and thus increasing pressure drops or even blocking the production line. With those issues in mind, the present work proposes a stationary model to predict the mixture temperature distribution and the two-phase flow heat transfer coefficient based on the mass, momentum and energy conservation equations applied to different unit cell regions. The main contribution of the present work is the modeling of the thermal scooping phenomenon, i.e., the heat transfer between two adjacent unit cells due to the mass flux known as scooping. The model was implemented as a structured Fortran95 code with an upwind difference scheme. The results were compared to experimental data and presented good agreement. The analysis showed that the inclusion of the scooping phenomenon into the model resulted in an averaged 8% improvement in the temperature gradient calculation and heat transfer coefficient prediction for the flowing mixture.

  4. Simulation of horizontal pipe two-phase slug flows using the two-fluid model

    Energy Technology Data Exchange (ETDEWEB)

    Ortega Malca, Arturo J. [Pontificia Univ. Catolica do Rio de Janeiro, RJ (Brazil). Dept. de Engenharia Mecanica. Nucleo de Simulacao Termohidraulica de Dutos (SIMDUT); Nieckele, Angela O. [Pontificia Univ. Catolica do Rio de Janeiro, RJ (Brazil). Dept. de Engenharia Mecanica

    2005-07-01

    Slug flow occurs in many engineering applications, mainly in the transport of hydrocarbon fluids in pipelines. The intermittency of slug flow causes severe unsteady loading on the pipelines carrying the fluids, which gives rise to design problems. Therefore, it is important to be able to predict the onset and development of slug flow as well as slug characteristics. The present work consists in the simulation of two-phase flow in slug pattern through horizontal pipes using the two-fluid model in its transient and one-dimensional form. The advantage of this model is that the flow field is allowed to develop naturally from a given initial conditions as part of the transient calculation; the slug evolves automatically as a product of the computed flow development. Simulations are then carried out for a large number of flow conditions that lead a slug flow. (author)

  5. Investigation of vertical slug flow with advanced two-phase flow instrumentation

    International Nuclear Information System (INIS)

    Mi, Y.; Ishii, M.; Tsoukalas, L.H.

    2001-01-01

    Extensive experiments of vertical slug flow were carried out with an electromagnetic flowmeter and an impedance void-meter in an air-water two-phase experimental loop. The basic principles of these instruments in vertical slug flow measurements are discussed. Time series of the liquid velocity and the impedance were separated into two parts corresponding to the Taylor bubble and the liquid slug. Characteristics of slug flow, such as the void fractions, probabilities and lengths of the Taylor bubble and liquid slug, slug unit velocity, area-averaged liquid velocity, and liquid film velocity of the Taylor bubble tail, etc., were obtained. For the first time, the area-averaged liquid velocity of slug flow was revealed by the electromagnetic flowmeter. It is realized that the void fraction of the liquid slug is determined by the turbulent intensity due to the relative liquid motion between the Taylor bubble tail region and its wake region. A correlation of the void fraction of the liquid slug is developed based on experimental results obtained from a test section with 50.8 mm i.d. The results of this study suggest a promising improvement in understanding of vertical slug flow

  6. Carbon-steel corrosion in multiphase slug flow and CO2

    International Nuclear Information System (INIS)

    Villarreal, J.; Laverde, D.; Fuentes, C.

    2006-01-01

    Hydrocarbon multiphase flow may exhibit various geometric configurations or flow patterns. One of these flow patterns is known as multiphase slug flow. If CO 2 is present in hydrocarbons, the steel pipelines can be corroded as this process is probably enhanced by slug flow turbulence. A hydrodynamic circuit was built to study the CO 2 corrosion rates under different slug flow conditions. The experimental results show how the corrosion rate of a carbon-steel electrode varies according to the flow turbulence. The higher slug frequency used in this study was 80 slugs/min. Experimental results for pressure drop and slug length are in agreement with the Dukler and Hubbard [A model for gas-liquid slug flow in horizontal and near horizontal tubes, Ind. Eng. Chem. Fundam. 14 (1975) 337-347] multiphase flow model. Furthermore, the experimental slug frequencies are well correlated by the Shell and Gregory [Correlation of the liquid volume fraction in the slug for horizontal gas-liquid slug flow. Int. J. Multiphase Flow 4 (1978) 33-39] equations in horizontal pipes

  7. Role of the Slug Transcription Factor in Chemically-Induced Skin Cancer

    Directory of Open Access Journals (Sweden)

    Kristine von Maltzan

    2016-02-01

    Full Text Available The Slug transcription factor plays an important role in ultraviolet radiation (UVR-induced skin carcinogenesis, particularly in the epithelial-mesenchymal transition (EMT occurring during tumor progression. In the present studies, we investigated the role of Slug in two-stage chemical skin carcinogenesis. Slug and the related transcription factor Snail were expressed at high levels in skin tumors induced by 7,12-dimethylbenz[α]anthracene application followed by 12-O-tetradecanoylphorbol-13-acetate (TPA treatment. TPA-induced transient elevation of Slug and Snail proteins in normal mouse epidermis and studies in Slug transgenic mice indicated that Slug modulates TPA-induced epidermal hyperplasia and cutaneous inflammation. Although Snail family factors have been linked to inflammation via interactions with the cyclooxygenase-2 (COX-2 pathway, a pathway that also plays an important role in skin carcinogenesis, transient TPA induction of Slug and Snail appeared unrelated to COX-2 expression. In cultured human keratinocytes, TPA induced Snail mRNA expression while suppressing Slug expression, and this differential regulation was due specifically to activation of the TPA receptor. These studies show that Slug and Snail exhibit similar patterns of expression during both UVR and chemical skin carcinogenesis, that Slug and Snail can be differentially regulated under some conditions and that in vitro findings may not recapitulate in vivo results.

  8. Slug flow model for infiltration into fractured porous media

    International Nuclear Information System (INIS)

    Martinez, M.J.

    1999-01-01

    A model for transient infiltration into a periodically fractured porous layer is presented. The fracture is treated as a permeable-walled slot and the moisture distribution is in the form of a slug being an advancing meniscus. The wicking of moisture from the fracture to the unsaturated porous matrix is a nonlinear diffusion process and is approximately by self-similar solutions. The resulting model is a nonlinear Volterra integral equation with a weakly singular kernel. Numerical analysis provides solutions over a wide range of the parameter space and reveals the asymptotic forms of the penetration of this slug in terms of dimensionless variables arising in the model. The numerical solutions corroborate asymptotic results given earlier by Nitao and Buscheck (1991), and by Martinez (1988). Some implications for the transport of liquid in fractured rock are discussed

  9. An analytic data analysis method for oscillatory slug tests.

    Science.gov (United States)

    Chen, Chia-Shyun

    2006-01-01

    An analytical data analysis method is developed for slug tests in partially penetrating wells in confined or unconfined aquifers of high hydraulic conductivity. As adapted from the van der Kamp method, the determination of the hydraulic conductivity is based on the occurrence times and the displacements of the extreme points measured from the oscillatory data and their theoretical counterparts available in the literature. This method is applied to two sets of slug test response data presented by Butler et al.: one set shows slow damping with seven discernable extremities, and the other shows rapid damping with three extreme points. The estimates of the hydraulic conductivity obtained by the analytic method are in good agreement with those determined by an available curve-matching technique.

  10. Analysis of slug tests in formations of high hydraulic conductivity.

    Science.gov (United States)

    Butler, James J; Garnett, Elizabeth J; Healey, John M

    2003-01-01

    A new procedure is presented for the analysis of slug tests performed in partially penetrating wells in formations of high hydraulic conductivity. This approach is a simple, spreadsheet-based implementation of existing models that can be used for analysis of tests from confined or unconfined aquifers. Field examples of tests exhibiting oscillatory and nonoscillatory behavior are used to illustrate the procedure and to compare results with estimates obtained using alternative approaches. The procedure is considerably simpler than recently proposed methods for this hydrogeologic setting. Although the simplifications required by the approach can introduce error into hydraulic-conductivity estimates, this additional error becomes negligible when appropriate measures are taken in the field. These measures are summarized in a set of practical field guidelines for slug tests in highly permeable aquifers.

  11. Statistical criterion for Bubbly-slug flow transition

    Energy Technology Data Exchange (ETDEWEB)

    Zigler, J; Elias, E [Technion-Israel Inst. of Tech., Haifa (Israel). Dept. of Mechanical Engineering

    1996-12-01

    The investigation of flow pattern transitions is still an interesting problem in the research of multiphase Row. It has been studied theoretically, and experimental confirmation of the models has been found by many investigators. The present paper deals with a statistical approach to bubbly-slug transitions in a vertical upward two phase flow and a new transition criterion is deduced from experimental data (authors).

  12. Direct contact condensation induced transition from stratified to slug flow

    International Nuclear Information System (INIS)

    Strubelj, Luka; Ezsoel, Gyoergy; Tiselj, Iztok

    2010-01-01

    Selected condensation-induced water hammer experiments performed on PMK-2 device were numerically modelled with three-dimensional two-fluid models of computer codes NEPTUNE C FD and CFX. Experimental setup consists of the horizontal pipe filled with the hot steam that is being slowly flooded with cold water. In most of the experimental cases, slow flooding of the pipe was abruptly interrupted by a strong slugging and water hammer, while in the selected experimental runs performed at higher initial pressures and temperatures that are analysed in the present work, the transition from the stratified into the slug flow was not accompanied by the water hammer pressure peak. That makes these cases more suitable tests for evaluation of the various condensation models in the horizontally stratified flows and puts them in the range of the available CFD (Computational Fluid Dynamics) codes. The key models for successful simulation appear to be the condensation model of the hot vapour on the cold liquid and the interfacial momentum transfer model. The surface renewal types of condensation correlations, developed for condensation in the stratified flows, were used in the simulations and were applied also in the regions of the slug flow. The 'large interface' model for inter-phase momentum transfer model was compared to the bubble drag model. The CFD simulations quantitatively captured the main phenomena of the experiments, while the stochastic nature of the particular condensation-induced water hammer experiments did not allow detailed prediction of the time and position of the slug formation in the pipe. We have clearly shown that even the selected experiments without water hammer present a tough test for the applied CFD codes, while modelling of the water hammer pressure peaks in two-phase flow, being a strongly compressible flow phenomena, is beyond the capability of the current CFD codes.

  13. A conservative fully implicit algorithm for predicting slug flows

    Science.gov (United States)

    Krasnopolsky, Boris I.; Lukyanov, Alexander A.

    2018-02-01

    An accurate and predictive modelling of slug flows is required by many industries (e.g., oil and gas, nuclear engineering, chemical engineering) to prevent undesired events potentially leading to serious environmental accidents. For example, the hydrodynamic and terrain-induced slugging leads to unwanted unsteady flow conditions. This demands the development of fast and robust numerical techniques for predicting slug flows. The presented in this paper study proposes a multi-fluid model and its implementation method accounting for phase appearance and disappearance. The numerical modelling of phase appearance and disappearance presents a complex numerical challenge for all multi-component and multi-fluid models. Numerical challenges arise from the singular systems of equations when some phases are absent and from the solution discontinuity when some phases appear or disappear. This paper provides a flexible and robust solution to these issues. A fully implicit formulation described in this work enables to efficiently solve governing fluid flow equations. The proposed numerical method provides a modelling capability of phase appearance and disappearance processes, which is based on switching procedure between various sets of governing equations. These sets of equations are constructed using information about the number of phases present in the computational domain. The proposed scheme does not require an explicit truncation of solutions leading to a conservative scheme for mass and linear momentum. A transient two-fluid model is used to verify and validate the proposed algorithm for conditions of hydrodynamic and terrain-induced slug flow regimes. The developed modelling capabilities allow to predict all the major features of the experimental data, and are in a good quantitative agreement with them.

  14. Challenges in Slug Modeling and Control for Offshore Oil and Gas Productions

    DEFF Research Database (Denmark)

    Pedersen, Simon; Løhndorf, Petar Durdevic; Yang, Zhenyu

    2017-01-01

    The upstream offshore multi-phase well-pipeline-riser installations are facing huge challenges related to slugging flow: An unstable flow regime where the flow rates, pressures and temperatures oscillate in the multi-phase pipelines. One typical severe slug is induced by vertical wells or risers...... most models require specific facility and operating data which, unfortunately, often is not available from most offshore installations. Anti-slug control have been investigated for several decades in oil & gas industry, but many of these existing methods suffer the consequent risk of simultaneously...... reducing the oil & gas production. This paper concludes that slug is a well defined phenomenon, but even though it has been investigated for several decades the current anti-slug control methods still have problems related to robustness. It is predicted that slug-induced challenges will be even more severe...

  15. Experimental data for the slug two-phase flow characteristics in horizontal pipeline

    Directory of Open Access Journals (Sweden)

    Abdalellah O. Mohmmed

    2018-02-01

    Full Text Available The data presented in this article were the basis for the study reported in the research articles entitled “Statistical assessment of experimental observation on the slug body length and slug translational velocity in a horizontal pipe” (Al-Kayiem et al., 2017 [1] which presents an experimental investigation of the slug velocity and slug body length for air-water tow phase flow in horizontal pipe. Here, in this article, the experimental set-up and the major instruments used for obtaining the computed data were explained in details. This data will be presented in the form of tables and videos.

  16. Kinetics of gravity-driven slug flow in partially wettable capillaries of varying cross section

    Science.gov (United States)

    Nissan, Alon; Wang, Qiuling; Wallach, Rony

    2016-11-01

    A mathematical model for slug (finite liquid volume) motion in not-fully-wettable capillary tubes with sinusoidally varying cross-sectional areas was developed. The model, based on the Navier-Stokes equation, accounts for the full viscous terms due to nonuniform geometry, the inertial term, the slug's front and rear meniscus hysteresis effect, and dependence of contact angle on flow velocity (dynamic contact angle). The model includes a velocity-dependent film that is left behind the advancing slug, reducing its mass. The model was successfully verified experimentally by recording slug movement in uniform and sinusoidal capillary tubes with a gray-scale high-speed camera. Simulation showed that tube nonuniformity has a substantial effect on slug flow pattern: in a uniform tube it is monotonic and depends mainly on the slug's momentary mass/length; an undulating tube radius results in nonmonotonic flow characteristics. The static nonzero contact angle varies locally in nonuniform tubes owing to the additional effect of wall slope. Moreover, the nonuniform cross-sectional area induces slug acceleration, deceleration, blockage, and metastable-equilibrium locations. Increasing contact angle further amplifies the geometry effect on slug propagation. The developed model provides a modified means of emulating slug flow in differently wettable porous media for intermittent inlet water supply (e.g., raindrops on the soil surface).

  17. Plant-Wide Anti-Slug Control for Offshore Oil and Gas Processes

    DEFF Research Database (Denmark)

    Pedersen, Simon

    In offshore Oil & Gas production processes the undesired severe slug flow regime can be present. The negative impact of severe slug is crucial to the production rate and process safety. In this work, the severe slugs which occur in the well-pipeline-riser system are experimentally and theoretically...... better than the ones developed for Pt . Furthermore, an alternative transmitter is experimentally investigated for online slug detection and monitoring. The transmitter is an Electrical Resistance Tomography (ERT) sensor measuring the electrical resistance over the cross-area section...

  18. The E-cadherin repressor slug and progression of human extrahepatic hilar cholangiocarcinoma

    Directory of Open Access Journals (Sweden)

    Wang Xin-sheng

    2010-07-01

    Full Text Available Abstract Objectives This study explored the expression and function of Slug in human extrahepatic hilar cholangiocarcinoma (EHC to identify its role in tumor progression. Methods The expression of Snail and Slug mRNA in 52 human tissue samples of EHC was investigated. The mRNA of Snail and Slug were quantified using reverse transcriptase-PCR, and correlations with E-cadherin expression and clinicopathological factors were investigated. We then investigated transfection of Slug cDNA in endogenous E-cadherin-positive human EHC FRH0201 cells, selectively induced the loss of E-cadherin protein expression, and then small interfering RNA (siRNA for inhibition of Slug expression in endogenous Slug-positive human EHC QBC939 cells, selectively induced the loss of Slug protein expression. A Boyden chamber transwell assay was used for invasion. Results Slug mRNA was overexpressed in 18 cases (34.6% of EHC compared with adjacent noncancerous tissue. E-Cadherin protein expression determined in the same 52 cases by immunohistochemistry was significantly down-regulated in those cases with Slug mRNA overexpression (P = 0.0001. The tumor and nontumor ratio of Slug mRNA was correlated with nodal metastasis(p = 0.0102, distant metastasis (p = 0.0001and Survival time(p = 0.0443. However, Snail mRNA correlated with neither E-cadherin expression nor tumor invasiveness. By inhibiting Slug expression by RNA interference, we found that reduced Slug levels upregulated E-cadherin and decreased invasion in QBC939 cell. When the QBC939 cells was infected with Slug cDNA,, significant E-cadherin was downregulated and increased invasion in QBC939 cell. Conclusions The results suggested that Slug expression plays an important role in both the regulation of E-cadherin expression and in the acquisition of invasive potential in human EHC. Slug is possibly a potential target for an antitumor therapy blocking the functions of invasion and metastasis in human EHCs.

  19. Slug Flow Analysis in Vertical Large Diameter Pipes

    Science.gov (United States)

    Roullier, David

    The existence of slug flow in vertical co-current two-phase flow is studied experimentally and theoretically. The existence of slug flow in vertical direction implies the presence of Taylor bubbles separated by hydraulically sealed liquid slugs. Previous experimental studies such as Ombere-Ayari and Azzopardi (2007) showed the evidence of the non-existence of Taylor bubbles for extensive experimental conditions. Models developed to predict experimental behavior [Kocamustafaogullari et al. (1984), Jayanti and Hewitt. (1990) and Kjoolas et al. (2017)] suggest that Taylor bubbles may disappear at large diameters and high velocities. A 73-ft tall and 101.6-mm internal diameter test facility was used to conduct the experiments allowing holdup and pressure drop measurements at large L/D. Superficial liquid and gas velocities varied from 0.05-m/s to 0.2 m/s and 0.07 m/s to 7.5 m/s, respectively. Test section pressure varied from 38 psia to 84 psia. Gas compressibility effect was greatly reduced at 84 psia. The experimental program allowed to observe the flow patterns for flowing conditions near critical conditions predicted by previous models (air-water, 1016 mm ID, low mixture velocities). Flow patterns were observed in detail using wire-mesh sensor measurements. Slug-flow was observed for a narrow range of experimental conditions at low velocities. Churn-slug and churn-annular flows were observed for most of the experimental data-points. Cap-bubble flow was observed instead of bubbly flow at low vSg. Wire-mesh measurements showed that the liquid has a tendency to remain near to the walls. The standard deviation of radial holdup profile correlates to the flow pattern observed. For churn-slug flow, the profile is convex with a single maximum near the pipe center while it exhibits a concave shape with two symmetric maxima close to the wall for churn-annular flow. The translational velocity was measured by two consecutive wire-mesh sensor crosscorrelation. The results show

  20. Transformation of a Water Slug in Free Fall Under the Conditions of Exposure to an Air Flow Orthogonal to the Direction of the Slug Motion

    Science.gov (United States)

    Volkov, R. S.; Zabelin, M. V.; Kuznetsov, G. V.; Strizhak, P. A.

    2016-07-01

    An experimental study has been made of the influence of an orthogonal (side) air flow propagating with a velocity to 5 m/s on the phases of transformation of a water slug with an initial volume of 0.05-0.5 liter in free fall from a height of 3 m. Use was made of Phantom V411 and Phantom Miro M310 high-speed video cameras and a Tema Automotive software system with the function of continuous tracking. The laws of retardation of the phases of transformation of the water slug from the instant of formation to that of formation of a droplet cloud under the action of the air flow orthogonal to the direction of the slug motion, and also of the deceleration, removal, and destruction of the droplets and fragments of water separating from the slug surface, have been established.

  1. Context-Dependent Passive Avoidance Learning in the Terrestrial Slug Limax.

    Science.gov (United States)

    Fujisaki, Yuko; Matsuo, Ryota

    2017-12-01

    The terrestrial slug Limax has been used as a model animal for studying the neural mechanisms underlying associative olfactory learning. The slug also innately exhibits negative phototactic behavior using its eyes. In the present study, we developed an experimental paradigm for quantification of slug's negative phototaxis behavior, and investigated whether the nature of the negative phototaxis can be modified by learning experience. The experimental set-up consists of light and dark compartments, between which the slug can move freely. During conditioning, the slug was placed in the light compartment, and an aversive stimulus (quinidine sulfate solution) was applied when it reached the dark compartment. After a single conditioning session, the time to reach the dark compartment significantly increased when it was tested following 24 hr or one week. Protein synthesis inhibition immediately following the conditioning impaired the memory retention at one week but not at 24 hr. The retrieval of the memory was context-dependent, as the time to reach the dark compartment did not significantly increase if the slug was placed on a floor with a different texture in the memory retention test. If the aversive stimulus was applied when the slug was in the light compartment, the time to reach the dark compartment did not increase after 24 hr. This is the first report demonstrating the capability of the slug to form context-dependent passive avoidance memory that can be established in a single conditioning session.

  2. Online slug detection in multi-phase transportation pipelines using electrical tomography

    DEFF Research Database (Denmark)

    Pedersen, Simon; Mai, Christian; Hansen, Leif

    2015-01-01

    in the pipelines is a highly investigated topic. To eliminate the slug in an online manner real-time slug detection methods are often required. Traditionally topside pressure transmitters upstream a 3-phase separator have been used as the controlled variable. In this paper Electrical Resistivity Tomography (ERT...

  3. Online Slug Detection in Multi-phase Transportation Pipelines Using Electrical Tomography

    DEFF Research Database (Denmark)

    Pedersen, Simon; Mai, Christian; Hansen, Leif

    2015-01-01

    in the pipelines is a highly investigated topic. To eliminate the slug in an online manner real-time slug detection methods are often required. Traditionally topside pressure transmitters upstream a 3-phase separator have been used as the controlled variable. In this paper Electrical Resistivity Tomography (ERT...

  4. Long liquid slugs in stratified gas/liquid flow in horizontal and slightly inclined pipes

    NARCIS (Netherlands)

    Kadri, U.

    2009-01-01

    Long liquid slugs reaching several hundreds pipe diameter may appear when transporting gas and liquid in horizontal and near horizontal pipes. The long slugs cause system vibration and separation difficulties that may lead to operational failures. Identifying and predicting the time and length

  5. Hydrodynamics of slug flow in a vertical narrow rectangular channel under laminar flow condition

    International Nuclear Information System (INIS)

    Wang, Yang; Yan, Changqi; Cao, Xiaxin; Sun, Licheng; Yan, Chaoxing; Tian, Qiwei

    2014-01-01

    Highlights: • Slug flow hydrodynamics in a vertical narrow rectangular duct were investigated. • The velocity of trailing Taylor bubble undisturbed by the leading one was measured. • Correlation of Taylor bubble velocity with liquid slug length ahead it was proposed. • Evolution of length distributions of Taylor bubble and liquid slug was measured. • The model of predicted length distributions was applied to the rectangular channel. - Abstract: The hydrodynamics of gas–liquid two-phase slug flow in a vertical narrow rectangular channel with the cross section of 2.2 mm × 43 mm is investigated using a high speed video camera system. Simultaneous measurements of velocity and duration of Taylor bubble and liquid slug made it possible to determine the length distributions of the liquid slug and Taylor bubble. Taylor bubble velocity is dependent on the length of the liquid slug ahead, and an empirical correlation is proposed based on the experimental data. The length distributions of Taylor bubbles and liquid slugs are positively skewed (log-normal distribution) at all measuring positions for all flow conditions. A modified model based on that for circular tubes is adapted to predict the length distributions in the present narrow rectangular channel. In general, the experimental data is well predicted by the modified model

  6. Characterization of the slug flow formation in vertical-to-horizontal channels with obstructions

    International Nuclear Information System (INIS)

    Onder, E.N.

    2004-01-01

    This thesis presents the results of the work carried out to study the formation of slugs under conditions of vertical-to-horizontal counter-current flow with obstructions. A flow instability is the mechanism proposed for the formation of slugs in a co-current flow. However, to the best of author's knowledge no work has been carried out for the formation of slugs in a vertical-to-horizontal counter-current flow with obstructions. Despite the existence of a few studies on counter-current vertical-to-horizontal slug flow with obstructions, it is in particular of great importance in the area of nuclear reactor safety analysis of a CANDU reactor. A test section manufactured of 63.5 mm inner diameter (ID) plexiglass was used for this work. The test section consists of 2022 mm long vertical and 3327 mm long horizontal legs connected by a 90 o PVC elbow. The horizontal leg contains flanges in which an orifice may be installed. These flanges are located at the distance of 1110 mm and 2217 mm from the elbow. The experiments were carried out to study the frequency of the formation of slugs, the slug propagation velocity and the averaged void fraction of slugs. We also carried out experiments for the characterisation of the propagation of waves. This allowed us to obtain the initial conditions required by the present model in order to predict the formation of slugs. In this model, the initial profile of waves was used to start calculations. Therefore, the aim of these experiments was to obtain the initial profile of these waves. The comparison of the experimental data collected at the onset of flooding with that collected at the onset of slugging shows that the results are very close to each other. This reflects the fact that flooding is simultaneously accompanied by the formation of slugs in the horizontal leg. We found that, for a given liquid flow rate, the gas flow rate, necessary to form the slugs as well as to provoke flooding, decreases as the severity of the

  7. Influence of the initial conditions for the numerical simulation of two-phase slug flow

    Energy Technology Data Exchange (ETDEWEB)

    Pachas Napa, Alex A.; Morales, Rigoberto E.M.; Medina, Cesar D. Perea

    2010-07-01

    Multiphase flows in pipelines commonly show several patterns depending on the flow rate, geometry and physical properties of the phases. In oil production, the slug flow pattern is the most common among the others. This flow pattern is characterized by an intermittent succession in space and time of an aerated liquid slug and an elongated gas bubble with a liquid film. Slug flow is studied through the slug tracking model described as one-dimensional and Lagrangian frame referenced. In the model, the mass and the momentum balance equations are applied in control volumes constituted by the gas bubble and the liquid slug. Initial conditions must be determined, which need to reproduce the intermittence of the flow pattern. These initial conditions are given by a sequence of flow properties for each unit cell. Properties of the unit cell in initial conditions should reflect the intermittence, for which they can be analyzed in statistical terms. Therefore, statistical distributions should be obtained for the slug flow variables. Distributions are complemented with the mass balance and the bubble design model. The objective of the present work is to obtain initial conditions for the slug tracking model that reproduce a better adjustment of the fluctuating properties for different pipe inclinations (horizontal, vertical or inclined). The numerical results are compared with experimental data obtained by PFG/FEM/UNICAMP for air-water flow at 0 deg, 45 deg and 90 deg and good agreement is observed. (author)

  8. Experimental characterization of solid particle transport by slug flow using Particle Image Velocimetry

    International Nuclear Information System (INIS)

    Goharzadeh, A; Rodgers, P

    2009-01-01

    This paper presents an experimental study of gas-liquid slug flow on solid particle transport inside a horizontal pipe with two types of experiments conducted. The influence of slug length on solid particle transportation is characterized using high speed photography. Using combined Particle Image Velocimetry (PIV) with Refractive Index Matching (RIM) and fluorescent tracers (two-phase oil-air loop) the velocity distribution inside the slug body is measured. Combining these experimental analyses, an insight is provided into the physical mechanism of solid particle transportation due to slug flow. It was observed that the slug body significantly influences solid particle mobility. The physical mechanism of solid particle transportation was found to be discontinuous. The inactive region (in terms of solid particle transport) upstream of the slug nose was quantified as a function of gas-liquid composition and solid particle size. Measured velocity distributions showed a significant drop in velocity magnitude immediately upstream of the slug nose and therefore the critical velocity for solid particle lifting is reached further upstream.

  9. Production of a high-velocity water slug using an impacting technique

    Science.gov (United States)

    Dehkhoda, S.; Bourne, N. K.

    2014-02-01

    A pulsed water jet consists of a series of discrete water slugs travelling at high velocity. Immediately after striking a target, these slugs apply high-intensity, short-duration transient stress pulses reaching an amplitude known as the water hammer pressure, followed by low-intensity, long-duration stationary stress at a lower stagnation pressure. The magnitude and duration of the water hammer and stagnation pressures are controlled by the size and quality of the water slugs. The use of water jets for rock cutting in mining operations is a centuries-old technology; however, practical methods for producing high-energy water slugs repeatedly have proven difficult. This can be partly due to the fact that the geometrical properties of a jet and so its effectiveness in creating damage is controlled and influenced by the method that is employed to generate the water slugs. This paper investigates the quality of a single water slug produced using an impacting technique where a hammer strikes a piston, resting on top of a water-filled chamber. The coherence and integrity of the jet core was of concern in this study. The impact impulse of the formed water jet was measured in a Kel-F target material using an embedded PVDF (Polyvinylidene fluoride) shock gauge. The recorded stress waveform was then used to determine the unity and endurance of the water slug stream once travelled through air.

  10. Parameter studies to determine sensitivity of slug impact loads to properties of core surrounding structures

    International Nuclear Information System (INIS)

    Gvildys, J.

    1985-01-01

    A sensitivity study of the HCDA slug impact response of fast reactor primary containment to properties of core surrounding structures was performed. Parameters such as the strength of the radial shield material, mass, void, and compressibility properties of the gas plenum material, mass of core material, and mass and compressibility properties of the coolant were used as variables to determine the magnitude of the slug impact loads. The response of the reactor primary containment and the partition of energy were also given. A study was also performed using water as coolant to study the difference in slug impact loads

  11. A semi-analytical solution for slug tests in an unconfined aquifer considering unsaturated flow

    Science.gov (United States)

    Sun, Hongbing

    2016-01-01

    A semi-analytical solution considering the vertical unsaturated flow is developed for groundwater flow in response to a slug test in an unconfined aquifer in Laplace space. The new solution incorporates the effects of partial penetrating, anisotropy, vertical unsaturated flow, and a moving water table boundary. Compared to the Kansas Geological Survey (KGS) model, the new solution can significantly improve the fittings of the modeled to the measured hydraulic heads at the late stage of slug tests in an unconfined aquifer, particularly when the slug well has a partially submerged screen and moisture drainage above the water table is significant. The radial hydraulic conductivities estimated with the new solution are comparable to those from the KGS, Bouwer and Rice, and Hvorslev methods. In addition, the new solution also can be used to examine the vertical conductivity, specific storage, specific yield, and the moisture retention parameters in an unconfined aquifer based on slug test data.

  12. Review of Slug Detection, Modeling and Control Techniques for Offshore Oil & Gas Production Processes

    DEFF Research Database (Denmark)

    Pedersen, Simon; Løhndorf, Petar Durdevic; Yang, Zhenyu

    2015-01-01

    The current offshore oil & gas multi-phase production and transportation installations have big challenges related with the slugging flow: An unstable multi-phase flow regime where the flow rates, pressures and temperatures oscillate in the considered processes. Slug can be caused by different...... operating conditions and installation structures. The most severe slugs are often induced in long vertical risers or production wells, where liquid blocks gas at the riser/well base and correspondingly it causes the pressure to accumulate and hence originates the oscillating performance. There are many...... of these methods can simultaneously reduce the oil & gas production, which is a very big concern as the production rate is the key evaluation parameter for offshore production. We conclude that the slugging flow is a well-defined phenomenon, even though this subject has been extensively investigated in the past...

  13. UNDERWATER ANALYSIS OF IRRADIATED REACTOR SLUGS FOR Co-60 AND OTHER RADIONUCLIDES AT THE SAVANNAH RIVER SITE

    International Nuclear Information System (INIS)

    CASELLA, VITO

    2004-01-01

    Co-60 was produced in the Savannah River Site (SRS) reactors in the 1970s, and the irradiated cobalt reactor slugs were stored in a reactor basin at SRS. Since the activity rates of these slugs were not accurately known, assaying was required. A sodium iodide gamma detector was placed above a specially designed air collimator assembly, so that the slug was eight to nine feet from the detector and was shielded by the basin water. Also, 18 curium sampler slugs, used to produce Cm-244 from Pu-239, were to be disposed of with the cobalt slugs. The curium slugs were also analyzed with a High Purity Germanium (HPGE) detector in an attempt to identify any additional radionuclides produced from the irradiation. Co-60 concentrations were determined for reactor disassembly basin cobalt slugs and the 18 curium sampler slugs. The total Co-60 activity of all of the assayed slugs in this work summed to 31,783 curies on 9/15/03. From the Co-60 concentrations of the curium sampler slugs, the irradiation flux was determined for the known irradiation time. The amounts of Pu-238,-239,-240,-241,-242; Am-241,-243; and Cm-242,-244 produced were then obtained based on the original amount of Pu-239 irradiated

  14. Slug controls stem/progenitor cell growth dynamics during mammary gland morphogenesis.

    Directory of Open Access Journals (Sweden)

    Mayssa Nassour

    Full Text Available Morphogenesis results from the coordination of distinct cell signaling pathways controlling migration, differentiation, apoptosis, and proliferation, along stem/progenitor cell dynamics. To decipher this puzzle, we focused on epithelial-mesenchymal transition (EMT "master genes". EMT has emerged as a unifying concept, involving cell-cell adhesion, migration and apoptotic pathways. EMT also appears to mingle with stemness. However, very little is known on the physiological role and relevance of EMT master-genes. We addressed this question during mammary morphogenesis. Recently, a link between Slug/Snai2 and stemness has been described in mammary epithelial cells, but EMT master genes actual localization, role and targets during mammary gland morphogenesis are not known and we focused on this basic question.Using a Slug-lacZ transgenic model and immunolocalization, we located Slug in a distinct subpopulation covering about 10-20% basal cap and duct cells, mostly cycling cells, coexpressed with basal markers P-cadherin, CK5 and CD49f. During puberty, Slug-deficient mammary epithelium exhibited a delayed development after transplantation, contained less cycling cells, and overexpressed CK8/18, ER, GATA3 and BMI1 genes, linked to luminal lineage. Other EMT master genes were overexpressed, suggesting compensation mechanisms. Gain/loss-of-function in vitro experiments confirmed Slug control of mammary epithelial cell luminal differentiation and proliferation. In addition, they showed that Slug enhances specifically clonal mammosphere emergence and growth, cell motility, and represses apoptosis. Strikingly, Slug-deprived mammary epithelial cells lost their potential to generate secondary clonal mammospheres.We conclude that Slug pathway controls the growth dynamics of a subpopulation of cycling progenitor basal cells during mammary morphogenesis. Overall, our data better define a key mechanism coordinating cell lineage dynamics and morphogenesis, and

  15. INTERRELATION OF RHOMBICITY AND OCCURRENCE OF INTERNAL CRACKS AT CONTINUOUS CASTING OF SORTED SLUG

    Directory of Open Access Journals (Sweden)

    Ju. A. Samojlovich

    2008-01-01

    Full Text Available Analysis of deformations and stresses in cross section of sorted uninterruptedly-casted slugs at their solidification and cooling within limits of crystallizer with the aim of determination of possibilities for occurrence of internal cracks of diagonal type is carried out on basis of mathematical modeling, the peculiarities of the slug skin cooling at its shrinkage and separation from crystallizer wall are revealed.

  16. Slug silencing inhibited perineural invasion through regulation of EMMPRIN expression in human salivary adenoid cystic carcinoma.

    Science.gov (United States)

    Wu, Baolei; Wei, Jianhua; Hu, Zhiqiang; Shan, Chun; Wang, Lei; Zhang, Chenping; Yang, Xi; Yang, Xinjie; Lei, Delin

    2016-02-01

    Salivary adenoid cystic carcinoma (SACC) is the most frequent salivary gland malignancy with a unique characteristic that has been named perineural invasion (PNI). EMMPRIN is a transmembrane glycoprotein that has been demonstrated to promote PNI in SACC. Slug, one of the most effective promoters of the epithelial-to-mesenchymal transition (EMT), has been found to be associated with PNI in SACC. The aim of the present study was to investigate the roles and relationships of Slug, EMMPRIN, and E-cadherin in the PNI process of SACC. The expression levels of Slug, EMMPRIN, and E-cadherin in 115 primary SACC cases were statistically analyzed by immunohistochemistry. Simultaneously, the SACC cell line SACC-83 was transfected with recombinant plasmids of silencing Slug (si-Slug) and/or silencing EMMPRIN (si-EMMPRIN). The functions of Slug and EMMPRIN in the EMT and PNI process were assessed by reverse transcription PCR (RT-PCR), western blotting, morphological observation, scratch test, migration assay, and in vitro perineural invasion assay. The immunohistochemical statistics revealed that the high expression of Slug and EMMPRIN and the low expression of E-cadherin were significantly associated with the PNI of SACC (P EMMPRIN expression (P EMMPRIN expression were both significantly negatively associated with E-cadherin expression (P EMMPRIN silencing both significantly inhibited EMMPRIN expression but promoted E-cadherin expression in SACC-83 cells (P EMMPRIN, or both induced cell morphology changes and inhibited tumor cell motility and PNI ability in SACC-83 cells (P EMMPRIN and then upregulating E-cadherin in the PNI process of SACC. The present study indicated that Slug and EMMPRIN are potential biomarkers and therapeutic targets for the diagnosis and treatment of PNI in human SACC.

  17. Applicability of slug interference testing of hydraulic characterization of contaminated aquifer sites

    International Nuclear Information System (INIS)

    Spane, F.A.; Swanson, L.C.

    1993-10-01

    Aquifer test methods available for characterizing hazardous waste sites are sometimes restricted because of problems with disposal of contaminated groundwater. These problems, in part, have made slug tests a more desirable method of determining hydraulic properties at such sites. However, in higher permeability formations (i.e., transmissivities ≥ 1 x 10 -3 m 2 /s), slug test results often cannot be analyzed and give, at best, only a lower limit for transmissivity. A need clearly exists to develop test methods that can be used to characterize higher permeability aquifers without removing large amounts of contaminated groundwater. One hydrologic test method that appears to hold promise for characterizing such sites is the slug interference test. To assess the applicability of this test method for use in shallow alluvial aquifer systems, slug interference tests have been conducted, along with more traditional aquifer testing methods, at several Hanford multiple-well sites. Transmissivity values estimated from the slug interference tests were comparable (within a factor of 2 to 3) to values calculated using traditional testing methods, and made it possible to calculate the storativity or specific yield for the intervening test formation. The corroboration of test results indicates that slug interference testing is a viable hydraulic characterization method in transmissive alluvial aquifers, and may represent one of the few test methods that can be used in sensitive areas where groundwater is contaminated

  18. Integrity of high-velocity water slug generated by an impacting technique

    Science.gov (United States)

    Dehkhoda, Sevda; Bourne, Neil

    2013-06-01

    A pulsed water jet is a series of discrete water slugs travelling at high velocity. Immediately after striking a target, these slugs apply high-intensity, short-duration transient stress known as the water hammer pressure, followed by low-intensity, long-duration stationary stress at the stagnation pressure. The magnitude and duration of the water hammer and stagnation pressures are controlled by the size and quality of the water slugs. The use of water jets for rock cutting in mining operations is a centuries-old technology; however, practical methods for producing high-energy water slugs repeatedly have proven difficult. This can be partly due to the fact that the geometrical properties of a jet and so its effectiveness in creating damage is controlled and influenced by the method that is employed to generate the water slugs. This paper investigates the integrity of a single water slug produced using an impacting technique where a hammer strikes a piston, resting on top of a water-filled chamber. The coherence of the generated water pulse was of concern in this study. If repeated shock reflections within the chamber were transmitted or were carried into the internal geometry of nozzle, the emerging jet could pulsate. The impact impulse of the formed water jet was measured in a Kel-F target material using an embedded PVDF (Polyvinylidene fluoride) shock gauge. The recorded stress waveform was then used to study the quality and endurance of the water pulse stream as it travelled through air.

  19. Analysis of the formation mechanism of the slug and jet center hole of axisymmetric shaped charges

    Science.gov (United States)

    Baoxiang, Ren; Gang, Tao; Peng, Wen; Changxing, Du; Chunqiao, Pang; Hongbo, Meng

    2018-06-01

    In the jet formation process of axisymmetric shaped charges, the slug is also formed. There is always a central hole in the symmetry axis of the jet and slug. The phenomenon was rarely mentioned and analyzed by the classical theory of shaped charges. For this problem, this paper attempts to explain the existence of the central hole in the jet and slug. Based on the analysis of recovery slug, we know that the jet and slug are in solid state in the process of formation. Through the analysis of X-flash radiographs of the stretching jet and particulation fracture, it is confirmed that the center holes in the jet are also present. Meanwhile, through the analysis of the microstructure of the recovered slug, it is found that there is a wave disturbance near the surface of the central hole. It can be speculated that the wave disturbance also exist in the jet. This effect may be one of the reasons for jet breakup. Due to the presence of the central hole in the jet, the density deficit of the jet obtained by other tests is very reasonable.

  20. Stability Analysis of Reactive Multiphase Slug Flows in Microchannels

    Directory of Open Access Journals (Sweden)

    Alejandro A. Munera Parra

    2014-05-01

    Full Text Available Conducting multiphase reactions in micro-reactors is a promising strategy for intensifying chemical and biochemical processes. A major unresolved challenge is to exploit the considerable benefits offered by micro-scale operation for industrial scale throughputs by numbering-up whilst retaining the underlying advantageous flow characteristics of the single channel system in multiple parallel channels. Fabrication and installation tolerances in the individual micro-channels result in different pressure losses and, thus, a fluid maldistribution. In this work, an additional source of maldistribution, namely the flow multiplicities, which can arise in a multiphase reactive or extractive flow in otherwise identical micro-channels, was investigated. A detailed experimental and theoretical analysis of the flow stability with and without reaction for both gas-liquid and liquid-liquid slug flow has been developed. The model has been validated using the extraction of acetic acid from n-heptane with the ionic liquid 1-Ethyl-3-methylimidazolium ethyl sulfate. The results clearly demonstrate that the coupling between flow structure, the extent of reaction/extraction and pressure drop can result in multiple operating states, thus, necessitating an active measurement and control concept to ensure uniform behavior and optimal performance.

  1. Characterization of California Central Coast Aquifers using Pneumatic Slug Tests

    Science.gov (United States)

    Aurelius, S.; Platt, D.; Whetsler, B.; Malama, B.

    2017-12-01

    The recent prolonged drought in California, where about 75% of the population depends to some extent ongroundwater, has led to increased stresses on the state's groundwater resources due to reduced recharge andincreased abstraction to supplement dwindling surface water supplies for irrigation and other urban uses.These factors have conspired to cause historic lows in groundwater levels, lost aquifer storage capacity dueincreased potential for land subsidence, and degraded water quality in coastal aquifers faced with increasedrates of seawater intrusion. Groundwater accounts for about a third of the total water uses in California,with some coastal communities being 100% dependent on groundwater. Irrigation accounts for over 60%of all state groundwater withdrawals in California. In light of this, the state of California recently passedthe Sustainable Groundwater Management Act (SGMA) aimed at bringing the State's groundwater basinsinto sustainable regimes of abstraction, recharge and storage. Groundwater ow models are critical to thesuccessful implementation of the SGMA legislation. However, the usefulness of the models is severely limitedby a lack of detailed knowledge of aquifer properties at spatial scales that allow for accurate projections tobe made about groundwater basin sustainability by resource managers. We report here the results of highresolution pneumatic slug tests performed in two shallow aquifers in San Luis Obispo County on the CaliforniaCentral Coast to obtain detailed information about aquifer properties, including permeability and storage,and their spatial variability.

  2. Automatic discrimination of bubbles and slugs in two-phase gas-liquid flow and measurement of the respective velocities

    International Nuclear Information System (INIS)

    Fitremann, J.M.; Guilpin, C.; Postaire, J.

    1976-01-01

    The measurement of the interface velocity in a two-phase gas-liquid flow is a difficult problem, owing to the dispersion of the velocity components of individual bubbles, gas-slugs, droplets, waves, etc. An entirely automatic method is presented, it gives the velocity of slugs and bubbles independently, by discrimination of local phase probe signals into a 'slug' signal and a 'bubble' signal feeding a shape-recognition program. Both discriminated void fractions are also calculated by the apparatus [fr

  3. Understanding the formation process of the liquid slug in a hilly-terrain wet natural gas pipeline

    DEFF Research Database (Denmark)

    Yang, Yan; Li, Jingbo; Wang, Shuli

    2017-01-01

    condition on the liquid slug formation is discussed including pipe diameter, inclination angle, gas superficial velocity and liquid holdup. The results show that the pipe is blocked by the liquid slug at the moment of slug formed. The pipe pressure suddenly increases, and then decreases gradually...... in the process of liquid slug formation and motion. The pipe pressure drop and liquid holdup decrease along with the increasing inclination angle of ascending pipe. On the contrary, they rise with the increase of the inclination angle of descending pipe. Higher gas superficial velocity and liquid holdup result...

  4. Computational investigations of the mixing performance inside liquid slugs generated by a microfluidic T-junction.

    Science.gov (United States)

    Li, Yuehao; Reddy, Rupesh K; Kumar, Challa S S R; Nandakumar, Krishnaswamy

    2014-09-01

    Droplet-based microfluidics has gained extensive research interest as it overcomes several challenges confronted by conventional single-phase microfluidics. The mixing performance inside droplets/slugs is critical in many applications such as advanced material syntheses and in situ kinetic measurements. In order to understand the effects of operating conditions on the mixing performance inside liquid slugs generated by a microfluidic T-junction, we have adopted the volume of fluid method coupled with the species transport model to study and quantify the mixing efficiencies inside slugs. Our simulation results demonstrate that an efficient mixing process is achieved by the intimate collaboration of the twirling effect and the recirculating flow. Only if the reagents are distributed transversely by the twirling effect, the recirculating flow can bring in convection mechanism thus facilitating mixing. By comparing the mixing performance inside slugs at various operating conditions, we find that slug size plays the key role in influencing the mixing performance as it determines the amount of fluid to be distributed by the twirling effect. For the cases where short slugs are generated, the mixing process is governed by the fast convection mechanism because the twirling effect can distribute the fluid to the flow path of the recirculating flow effectively. For cases with long slugs, the mixing process is dominated by the slow diffusion mechanism since the twirling effect is insufficient to distribute the large amount of fluid. In addition, our results show that increasing the operating velocity has limited effects on improving the mixing performance. This study provides the insight of the mixing process and may benefit the design and operations of droplet-based microfluidics.

  5. Soliton wave model for simulating the slug formation in vertical-to-horizontal partially blocked pipes

    International Nuclear Information System (INIS)

    Nihan Onder; Alberto Teyssedou; Danila Roubtsov

    2005-01-01

    Full text of publication follows: In CANDU reactors the fuel channels are connected to inlet and outlet headers by feeder-pipes that consist of vertical and horizontal legs. In some feeders, orifices are installed for flow adjustment. During a postulated Loss of Coolant Accidents, the emergency cooling water injected into the inlet and outlet headers enters the fuel channels through the feeder pipes. Steam produced in the feeders and in the fuel channels may flow in the direction opposite to that of the water, thereby creating vertical to horizontal Counter-Current Flow (CCF). The rate at which the cooling water enters the fuel channel may be substantially limited by the flooding phenomena that entrains the water in the same direction as the steam flow. Steam flowing in the direction opposite to the cooling water can bring about the formation of slug flow. Long slugs of liquid moving at relatively high speed are transported back towards the headers by the steam. This phenomenon substantially reduces the amount of cooling water that can reach the reactor core. We conducted CCF experiments using a vertical-to-horizontal test section connected by 90 deg. elbows, with an orifice installed in the horizontal leg. Four different orifices were used to carry out the experiments. We have observed that soliton-type waves generated close to the elbow propagate in the horizontal leg towards the orifice, where a partial reflection takes place. Without an orifice, the soliton waves are reflected from the second elbow. The reflected waves move in the opposite direction to that of the incident wave. Since soliton-type waves are periodically generated, the incident and reflected waves interfere at some place in the horizontal leg. If the amplitude of the interference wave is high enough, the bridging of the tubes occur, which generates the slugs. During the experiments the water and air flow rates, pressures and void fraction distributions were measured. The slug propagation

  6. Herbivory of an invasive slug is affected by earthworms and the composition of plant communities.

    Science.gov (United States)

    Zaller, Johann G; Parth, Myriam; Szunyogh, Ilona; Semmelrock, Ines; Sochurek, Susanne; Pinheiro, Marcia; Frank, Thomas; Drapela, Thomas

    2013-05-13

    Biodiversity loss and species invasions are among the most important human-induced global changes. Moreover, these two processes are interlinked as ecosystem invasibility is considered to increase with decreasing biodiversity. In temperate grasslands, earthworms serve as important ecosystem engineers making up the majority of soil faunal biomass. Herbivore behaviour has been shown to be affected by earthworms, however it is unclear whether these effects differ with the composition of plant communities. To test this we conducted a mesocosm experiment where we added earthworms (Annelida: Lumbricidae) to planted grassland communities with different plant species composition (3 vs. 12 plant spp.). Plant communities had equal plant densities and ratios of the functional groups grasses, non-leguminous forbs and legumes. Later, Arion vulgaris slugs (formerly known as A. lusitanicus; Gastropoda: Arionidae) were added and allowed to freely choose among the available plant species. This slug species is listed among the 100 worst alien species in Europe. We hypothesized that (i) the food choice of slugs would be altered by earthworms' specific effects on the growth and nutrient content of plant species, (ii) slug herbivory will be less affected by earthworms in plant communities containing more plant species than in those with fewer plant species because of a more readily utilization of plant resources making the impacts of earthworms less pronounced. Slug herbivory was significantly affected by both earthworms and plant species composition. Slugs damaged 60% less leaves when earthworms were present, regardless of the species composition of the plant communities. Percent leaf area consumed by slugs was 40% lower in communities containing 12 plant species; in communities containing only three species earthworms increased slug leaf area consumption. Grasses were generally avoided by slugs. Leaf length and number of tillers was increased in mesocosms containing more plant

  7. An evaluation of slug interference tests for aquifer characterization at the Hanford Site

    International Nuclear Information System (INIS)

    Spane, F.A. Jr.; Thorne, P.D.

    1992-01-01

    Slug interference tests are conducted by instantaneously changing the water level in a well and monitoring the aquifer response at one or more observation wells. The applicability of this method for hydraulic characterization of a high permeability unconfined aquifer at the Hanford Site was evaluated. Analytical techniques were used to predict slug interference responses over a range of aquifer hydraulic conditions and observation well distances. This was followed by a field test of the proposed technique. The results showed that slug interference testing can be used to characterize aquifers having transmissivities up to 10 -1 m 2 /s compared to a maximum transmissivity of about 10 -3 m 2 /s for single-well slug tests. The amplitude of the pressure response measured at the observation well is primarily determined by aquifer storativity, while the time-lag of the pressure peak is mainly controlled by the transmissivity. Several recommendations are made optimizing the results of slug interference tests in higher permeability, unconfined to semiconfined aquifers

  8. SLUG-STOCHASTICALLY LIGHTING UP GALAXIES. I. METHODS AND VALIDATING TESTS

    Energy Technology Data Exchange (ETDEWEB)

    Da Silva, Robert L.; Fumagalli, Michele; Krumholz, Mark [Department of Astronomy and Astrophysics, UCO/Lick Observatory, University of California, 1156 High Street, Santa Cruz, CA 95064 (United States)

    2012-02-01

    The effects of stochasticity on the luminosities of stellar populations are an often neglected but crucial element for understanding populations in the low-mass or the low star formation rate regime. To address this issue, we present SLUG, a new code to 'Stochastically Light Up Galaxies'. SLUG synthesizes stellar populations using a Monte Carlo technique that properly treats stochastic sampling including the effects of clustering, the stellar initial mass function, star formation history, stellar evolution, and cluster disruption. This code produces many useful outputs, including (1) catalogs of star clusters and their properties such as their stellar initial mass distributions and their photometric properties in a variety of filters, (2) two dimensional histograms of color-magnitude diagrams of every star in the simulation, and (3) the photometric properties of field stars and the integrated photometry of the entire simulated galaxy. After presenting the SLUG algorithm in detail, we validate the code through comparisons with STARBURST99 in the well-sampled regime, and with observed photometry of Milky Way clusters. Finally, we demonstrate SLUG's capabilities by presenting outputs in the stochastic regime. SLUG is publicly distributed through the Web site http://sites.google.com/site/runslug/.

  9. Cell-State Transitions Regulated by SLUG Are Critical for Tissue Regeneration and Tumor Initiation

    Directory of Open Access Journals (Sweden)

    Sarah Phillips

    2014-05-01

    Full Text Available Perturbations in stem cell activity and differentiation can lead to developmental defects and cancer. We use an approach involving a quantitative model of cell-state transitions in vitro to gain insights into how SLUG/SNAI2, a key developmental transcription factor, modulates mammary epithelial stem cell activity and differentiation in vivo. In the absence of SLUG, stem cells fail to transition into basal progenitor cells, while existing basal progenitor cells undergo luminal differentiation; together, these changes result in abnormal mammary architecture and defects in tissue function. Furthermore, we show that in the absence of SLUG, mammary stem cell activity necessary for tissue regeneration and cancer initiation is lost. Mechanistically, SLUG regulates differentiation and cellular plasticity by recruiting the chromatin modifier lysine-specific demethylase 1 (LSD1 to promoters of lineage-specific genes to repress transcription. Together, these results demonstrate that SLUG plays a dual role in repressing luminal epithelial differentiation while unlocking stem cell transitions necessary for tumorigenesis.

  10. Influence of Catalysis and Oxidation on Slug Calorimeter Measurements in Arc Jets

    Science.gov (United States)

    Nawaz, Anuscheh; Driver, Dave; TerrazasSalinas, Imelda

    2012-01-01

    Arc jet tests play a critical role in the characterization and certification of thermal protection materials and systems (TPS). The results from these arc jet tests feed directly into computational models of material response and aerothermodynamics to predict the performance of the TPS in flight. Thus the precise knowledge of the plasma environment to which the test material is subjected, is invaluable. As one of the environmental parameters, the heat flux is commonly measured. The measured heat flux is used to determine the plasma enthalpy through analytical or computational models. At NASA Ames Research Center (ARC), slug calorimeters of a geometrically similar body to the test article are routinely used to determine the heat flux. A slug calorimeter is a thermal capacitance-type calorimeter that uses the temperature rise in a thermally insulated slug to determine the heat transfer rate, see Figure 1(left). Current best practices for measuring the heat flux with a slug calorimeter are described in ASTM E457 - 96. Both the calorimeter body and slug are made of Oxygen Free High Conductivity Copper, and are cleaned before each run.

  11. Modelling and control of growing slugs in horizontal multiphase pipe flows

    Directory of Open Access Journals (Sweden)

    Steinar M. Elgsæter

    2006-07-01

    Full Text Available In this paper, the use of active control to restrict the length of growing slugs in horizontal pipelines is investigated. Specifically, the paper attempts to determine if such control can be attained with realistic measurements and actuators. Simulations in OLGA2000 show that a feedback controller can use measurements or estimates of slug length to control the growth of a slug in a horizontal pipeline by partially closing inlet or outlet chokes. A control-volume approach is used to develop a low-order model of inlet choke-slug growth dynamics based on mass- and impulse balances. The resulting model is a system of nonlinear differential-algebraic equations, which is suitable for observer-design. The tuned model is found to be in good agreement with experiments and OLGA2000-simulations. Linearizations of the model are found to be observable around realistic trajectories when rates and pressures at the inlet and outlet are measured. An extended Luenberger-observer is shown to give good estimates of slug length and -position in simulations even under model uncertainty.

  12. Information content of slug tests for estimating hydraulic properties in realistic, high-conductivity aquifer scenarios

    Science.gov (United States)

    Cardiff, Michael; Barrash, Warren; Thoma, Michael; Malama, Bwalya

    2011-06-01

    SummaryA recently developed unified model for partially-penetrating slug tests in unconfined aquifers ( Malama et al., in press) provides a semi-analytical solution for aquifer response at the wellbore in the presence of inertial effects and wellbore skin, and is able to model the full range of responses from overdamped/monotonic to underdamped/oscillatory. While the model provides a unifying framework for realistically analyzing slug tests in aquifers (with the ultimate goal of determining aquifer properties such as hydraulic conductivity K and specific storage Ss), it is currently unclear whether parameters of this model can be well-identified without significant prior information and, thus, what degree of information content can be expected from such slug tests. In this paper, we examine the information content of slug tests in realistic field scenarios with respect to estimating aquifer properties, through analysis of both numerical experiments and field datasets. First, through numerical experiments using Markov Chain Monte Carlo methods for gauging parameter uncertainty and identifiability, we find that: (1) as noted by previous researchers, estimation of aquifer storage parameters using slug test data is highly unreliable and subject to significant uncertainty; (2) joint estimation of aquifer and skin parameters contributes to significant uncertainty in both unless prior knowledge is available; and (3) similarly, without prior information joint estimation of both aquifer radial and vertical conductivity may be unreliable. These results have significant implications for the types of information that must be collected prior to slug test analysis in order to obtain reliable aquifer parameter estimates. For example, plausible estimates of aquifer anisotropy ratios and bounds on wellbore skin K should be obtained, if possible, a priori. Secondly, through analysis of field data - consisting of over 2500 records from partially-penetrating slug tests in a

  13. Heat transfer to air-water two-phase flow in slug/churn region

    International Nuclear Information System (INIS)

    Wadekar, V.V.; Tuzla, K.; Chen, J.C.

    1996-01-01

    Measured heat transfer data for air-water two-phase flow in the slug/churn flow region are reported. The measurements were obtained from a 1.3 m tall, 15.7 mm diameter vertical tube test-section. It is observed that the data exhibit different heat transfer characteristics to those predicted by the standard correlations for the convective component of flow boiling heat transfer. Comparison with the predictions of a slug flow model for evaporation shows a significant overprediction of the data. The reason for the overprediction is attributed to the sensible heating requirement of the gas phase. The slug flow model is therefore suitably modified for non-evaporating two-phase flow. This specially adapted model is found to give reasonably good predictions of the measured data

  14. Influence of riser-induced slugs on the downstream separation processes

    DEFF Research Database (Denmark)

    Pedersen, Simon; Løhndorf, Petar Durdevic; Yang, Zhenyu

    2017-01-01

    In Oil & Gas installations the severe slug is an undesired flow regime due to the negative impact on the production rate and facility safety. This study will evaluate the severe riser-induced slugs’ influence to a typical separation process, consisting of a 3-phase gravity separator physically...... linked to a de-oiling hydrocyclone, based on experimental tests performed on a laboratory testing facility. Several scenarios are compared, while three PID controllers’ coefficients are kept constant for all the tests: The separator pressure, water level, and hydrocyclone pressure-drop-ratio (PDR......) controllers. Each respective scenario makes a comparison between uncontrolled, open-, and closed-loop anti-slug control configurations. It is concluded that both open- and closed-loop anti-slug control strategies improve the water level and PDR setpoint tracking equally well, but that the closed-loop strategy...

  15. Aldolase catalyzed L-phenylserine synthesis in a slug-flow microfluidic system - Performance and diastereoselectivity studies

    NARCIS (Netherlands)

    Čech, J.; Hessel, V.; Přibyl, M.

    2017-01-01

    We study synthesis of . L-phenylserine catalyzed by the enzyme . L-threonine aldolase in a slug-flow microfluidic system. Slug-flow arrangement allows for the continuous refilling of sparingly soluble substrate (benzaldehyde) into an aqueous reaction mixture. We identified suitable composition of an

  16. The Gastropod Menace: Slugs on Brassica Plants Affect Caterpillar Survival through Consumption and Interference with Parasitoid Attraction.

    Science.gov (United States)

    Desurmont, Gaylord A; Zemanova, Miriam A; Turlings, Ted C J

    2016-03-01

    Terrestrial molluscs and insect herbivores play a major role as plant consumers in a number of ecosystems, but their direct and indirect interactions have hardly been explored. The omnivorous nature of slugs makes them potential disrupters of predator-prey relationships, as a direct threat to small insects and through indirect, plant-mediated effects. Here, we examined the effects of the presence of two species of slugs, Arion rufus (native) and A. vulgaris (invasive) on the survivorship of young Pieris brassicae caterpillars when feeding on Brassica rapa plants, and on plant attractiveness to the main natural enemy of P. brassicae, the parasitoid Cotesia glomerata. In two separate predation experiments, caterpillar mortality was significantly higher on plants co-infested with A. rufus or A. vulgaris. Moreover, caterpillar mortality correlated positively with slug mass and leaf consumption by A. vulgaris. At the third trophic level, plants infested with slugs and plants co-infested with slugs and caterpillars were far less attractive to parasitoids than plants damaged by caterpillars only, independently of slug species. Chemical analyses confirmed that volatile emissions, which provide foraging cues for parasitoids, were strongly reduced in co-infested plants. Our study shows that the presence of slugs has the potential to affect insect populations, directly via consumptive effects, and indirectly via changes in plant volatiles that result in a reduced attraction of natural enemies. The fitness cost for P. brassicae imposed by increased mortality in presence of slugs may be counterbalanced by the benefit of escaping its parasitoids.

  17. Control of slug damage to oilseed rape and wheat with imidacloprid seed dressings in laboratory and field experiments

    NARCIS (Netherlands)

    Simms, L.C.; Ester, A.; Wilson, M.J.

    2006-01-01

    Slugs are common pests of oilseed and cereal crops in Europe and are currently controlled using bait pellets that often fail to give adequate protection: Here we investigate the potential of the broad-spectrum insecticide imidacloprid, previously suggested to have activity against slugs, to control

  18. A mini slug test method for determination of a local hydraulic conductivity of an unconfined sandy aquifer

    DEFF Research Database (Denmark)

    Hinsby, Klaus; Bjerg, Poul Løgstrup; Andersen, Lars J.

    1992-01-01

    distributed measurements of a local hydraulic conductivity at a tracer test site at Vejen, Denmark. The mini slug test results calculated by a modified Dax slug test analysing method, applying the elastic storativity in the Dax equations instead of the specific yield, are in good accordance with the results...

  19. Image processing analysis on the air-water slug two-phase flow in a horizontal pipe

    Science.gov (United States)

    Dinaryanto, Okto; Widyatama, Arif; Majid, Akmal Irfan; Deendarlianto, Indarto

    2016-06-01

    Slug flow is a part of intermittent flow which is avoided in industrial application because of its irregularity and high pressure fluctuation. Those characteristics cause some problems such as internal corrosion and the damage of the pipeline construction. In order to understand the slug characteristics, some of the measurement techniques can be applied such as wire-mesh sensors, CECM, and high speed camera. The present study was aimed to determine slug characteristics by using image processing techniques. Experiment has been carried out in 26 mm i.d. acrylic horizontal pipe with 9 m long. Air-water flow was recorded 5 m from the air-water mixer using high speed video camera. Each of image sequence was processed using MATLAB. There are some steps including image complement, background subtraction, and image filtering that used in this algorithm to produce binary images. Special treatments also were applied to reduce the disturbance effect of dispersed bubble around the bubble. Furthermore, binary images were used to describe bubble contour and calculate slug parameter such as gas slug length, gas slug velocity, and slug frequency. As a result the effect of superficial gas velocity and superficial liquid velocity on the fundamental parameters can be understood. After comparing the results to the previous experimental results, the image processing techniques is a useful and potential technique to explain the slug characteristics.

  20. Fluidization behavior in a circulating slugging fluidized bed reactor. Part I : residence time and residence time distribution of polyethylene solids

    NARCIS (Netherlands)

    Putten, van I.C.; Sint Annaland, van M.; Weickert, G.

    2007-01-01

    Square nosed slugging fluidization behavior in a circulating fluidized bed riser using a polyethylene powder with a very wide particle size distribution was studied. In square nosed slugging fluidization the extent of mixing of particles of different size depends on the riser diameter, gas velocity,

  1. Fluidization behavior in a circulating slugging fluidized bed reactor. Part I: Residence time and residence time distribution of polyethylene solids

    NARCIS (Netherlands)

    van Putten, I.C.; van Sint Annaland, M.; Weickert, G.

    2007-01-01

    Square nosed slugging fluidization behavior in a circulating fluidized bed riser using a polyethylene powder with a very wide particle size distribution was studied. In square nosed slugging fluidization the extent of mixing of particles of different size depends on the riser diameter, gas velocity,

  2. Dynamics of a two-phase flow through a minichannel: Transition from churn to slug flow

    Science.gov (United States)

    Górski, Grzegorz; Litak, Grzegorz; Mosdorf, Romuald; Rysak, Andrzej

    2016-04-01

    The churn-to-slug flow bifurcations of two-phase (air-water) flow patterns in a 2mm diameter minichannel were investigated. With increasing a water flow rate, we observed the transition of slugs to bubbles of different sizes. The process was recorded by a digital camera. The sequences of light transmission time series were recorded by a laser-phototransistor sensor, and then analyzed using the recurrence plots and recurrence quantification analysis (RQA). Due to volume dependence of bubbles velocities, we observed the formation of periodic modulations in the laser signal.

  3. Recreating Riser Slugging Flow Based on an Economic Lab-sized Setup

    DEFF Research Database (Denmark)

    Hansen, Lasse; Pedersen, Simon; Yang, Zhenyu

    2013-01-01

    As a kind of periodic phenomenon, the slugging flow in the offshore oil & gas production addresses a lot of attentions, due to its limitation of production rate, periodic overload processing facilities, and even direct cause of emergent shutdown. This work studies the emulation of the riser...... slugging flow in the offshore oil & gas production, by constructing an economical lab-sized setup in the university campus. Firstly, the construction and used components for the lab setup are illustrated; then, the constructed setup is validated by checking the consistency with some existing typical riser...

  4. The unique deep sea—land connection: interactive 3D visualization and molecular phylogeny of Bathyhedyle boucheti n. sp. (Bathyhedylidae n. fam.—the first panpulmonate slug from bathyal zones

    Directory of Open Access Journals (Sweden)

    Timea P. Neusser

    2016-12-01

    Full Text Available The deep sea comprises vast unexplored areas and is expected to conceal significant undescribed invertebrate species diversity. Deep waters may act as a refuge for many relictual groups, including elusive and enigmatic higher taxa, but the evolutionary pathways by which colonization of the deep sea has occurred have scarcely been investigated. Sister group relationships between shallow water and deep sea taxa have been documented in several invertebrate groups, but are unknown between amphibious/terrestrial and deep-sea species. Here we describe in full and interactive 3D morphoanatomical detail the new sea slug species Bathyhedyle boucheti n. sp., dredged from the continental slope off Mozambique. Molecular and morphological analyses reveal that it represents a novel heterobranch gastropod lineage which we establish as the new family Bathyhedylidae. The family is robustly supported as sister to the recently discovered panpulmonate acochlidian family Aitengidae, which comprises amphibious species living along the sea shore as well as fully terrestrial species. This is the first marine-epibenthic representative among hedylopsacean Acochlidiida, the first record of an acochlidian from deep waters and the first documented panpulmonate deep-sea slug. Considering a marine mesopsammic ancestor, the external morphological features of Bathyhedyle n. gen. may be interpreted as independent adaptations to a benthic life style in the deep sea, including the large body size, broad foot and propodial tentacles. Alternatively, the common ancestor of Bathyhedylidae and Aitengidae may have been a macroscopic amphibious or even terrestrial species. We hypothesize that oophagy in the common ancestor of Aitengidae and Bathyhedylidae might explain the impressive ecological and evolutionary flexibility in habitat choice in the Acochlidiida.

  5. Model for melt blockage (slug) relocation and physico-chemical interactions during core degradation under severe accident conditions

    International Nuclear Information System (INIS)

    Veshchunov, M.S.; Shestak, V.E.

    2008-01-01

    The model describing massive melt blockage (slug) relocation and physico-chemical interactions with steam and surrounding fuel rods of a bundle is developed on the base of the observations in the CORA tests. Mass exchange owing to slug oxidation and fuel rods dissolution is described by the previously developed 2D model for the molten pool oxidation. Heat fluxes in oxidising melt along with the oxidation heat effect at the melt relocation front are counterbalanced by the heat losses in the surrounding media and the fusion heat effect of the Zr claddings attacked by the melt. As a result, the slug relocation velocity is calculated from the heat flux matches at the melt propagation front (Stefan problem). A numerical module simulating the slug behaviour is developed by tight coupling of the heat and mass exchange modules. The new model demonstrates a reasonable capability to simulate the main features of the massive slug behaviour observed in the CORA-W1 test

  6. Evaluation analysis of correlations for predicting the void fraction and slug velocity of slug flow in an inclined narrow rectangular duct

    Energy Technology Data Exchange (ETDEWEB)

    Yan, Chaoxing, E-mail: yanchaoxing0808@163.com [Fundamental Science on Nuclear Safety and Simulation Technology Laboratory, Harbin Engineering University, Harbin 150001 (China); Yan, Changqi, E-mail: Changqi_yan@163.com [Fundamental Science on Nuclear Safety and Simulation Technology Laboratory, Harbin Engineering University, Harbin 150001 (China); Shen, Yunhai [Science and Technology on Reactor System Design Technology Laboratory, Nuclear Power Institute of China, Chengdu 610041 (China); Sun, Licheng; Wang, Yang [Fundamental Science on Nuclear Safety and Simulation Technology Laboratory, Harbin Engineering University, Harbin 150001 (China)

    2014-07-01

    Highlights: • 46 void fraction correlations are evaluated on void fraction. • Evaluation of void fraction correlations on slug velocity is studied. • Effect of void fraction correlations on separated frictional pressure drop is studied. • Drift-flux type correlation shows best agreement with experimental data. • Evaluation is investigated in different flow regions. - Abstract: A visualized investigation was conducted on inclined upward air–water slug flow in a narrow rectangular duct with the cross section of 43 mm × 3.25 mm. The slug velocity and void fraction were obtained through image processing. 46 correlations for predicting void fraction, covering the types of slip ratio, Kβ, Lockhart and Martinelli, drift-flux and general were evaluated against the experimental data. In the experiment, four inclined conditions including 0°, 10°, 20° and 30° were investigated and the ranges of gas and liquid superficial velocity were 0.16–2.63 m/s and 0.12–3.59 m/s, respectively. The results indicate that the inclination has no significant influence on prediction error for a given correlation and the drift-flux type correlations are more competitive than the others in the prediction of slug velocity and void fraction. In addition, most of drift-flux type correlations are quite accurate in turbulent flow region, while they provide relative poor predictions in laminar flow region. As for the frictional pressure drop separated from the measured total pressure drop, the deviation arising from the calculation of the void fraction by different correlations is significant in laminar flow region, whereas is negligible in turbulent flow region.

  7. The mucosal toxicity of different benzalkonium chloride analogues evaluated with an alternative test using slugs.

    Science.gov (United States)

    Adriaens, E; Dierckens, K; Bauters, T G; Nelis, H J; van Goethem, F; Vanparys, P; Remon, J P

    2001-07-01

    The objective of this study was to evaluate the mucosal toxicity of different benzalkonium chloride (BAC) analogues using slugs as the alternative test organism. The effect of different BAC analogues on the mucosal tissue of slugs was determined from the protein, lactate dehydrogenase, and alkaline phosphatase released from the foot mucosa after treatment. Additionally, mucus production and reduction in body weight of the slugs were measured. The eye irritation potency of the molecules was evaluated with the Bovine Corneal Opacity and Permeability (BCOP) assay. The antimicrobial activity of the different BAC analogues was also assessed. All BAC analogues induced severe damage to the mucosal epithelium of the slugs, and the irritation increased with decreasing alkyl chain length: BAC-C16 or = BAC-C16 > BAC-C12. The BAC-C14 exhibited higher activity than the BAC-mix. The toxicity and activity of BAC analogues depend on the alkyl chain length. The use of BAC-C14 as a conservative agent in pharmaceutical preparations instead of the BAC-mix should be considered.

  8. Ultraviolet Radiation and the Slug Transcription Factor Induce Proinflammatory and Immunomodulatory Mediator Expression in Melanocytes

    Directory of Open Access Journals (Sweden)

    Stephanie H. Shirley

    2012-01-01

    Full Text Available Despite extensive investigation, the precise contribution of the ultraviolet radiation (UVR component of sunlight to melanoma etiology remains unclear. UVR induces keratinocytes to secrete proinflammatory and immunomodulatory mediators that promote inflammation and skin tumor development; expression of the slug transcription factor in keratinocytes is required for maximal production of these mediators. In the present studies we examined the possibility that UVR-exposed melanocytes also produce proinflammatory mediators and that Slug is important in this process. Microarray studies revealed that both UVR exposure and Slug overexpression altered transcription of a variety of proinflammatory mediators by normal human melanocytes; some of these mediators are also known to stimulate melanocyte growth and migration. There was little overlap in the spectra of cytokines produced by the two stimuli. However IL-20 was similarly induced by both stimuli and the NFκB pathway appeared to be important in both circumstances. Further exploration of UVR-induced and Slug-dependent pathways of cytokine induction in melanocytes may reveal novel targets for melanoma therapy.

  9. Mass transfer coefficient of slug flow for organic solvent-aqueous system in a microreactor

    Energy Technology Data Exchange (ETDEWEB)

    Tuek, Ana Jurinjak; Anic, Iva; Kurtanjek, Zelimir; Zelic, Bruno [University of Zagreb, Zagreb (Croatia)

    2015-06-15

    Application of microreactor systems could be the next break-through in the intensification of chemical and biochemical processes. The common flow regime for organic solvent-aqueous phase two-phase systems is a segmented flow. Internal circulations in segments cause high mass transfer and conversion. We analyzed slug flow in seven systems of organic solvents and aqueous phase. To analyze how slug lengths in tested systems depend on linear velocity and physical and chemical properties of used organic solvents, regression models were proposed. It was shown that models based on linearization of approximation by potentials give low correlation for slug length prediction; however, application of an essential nonlinear model of multiple layer perception (MLP) neural network gives high correlation with R{sup 2}=0.9. General sensitivity analysis was applied for the MLP neural network model, which showed that 80% of variance in slug length for the both phases is accounted for the viscosity and density of the organic phases; 10% is accounted by surface tension of the organic phase, while molecular masses and flow rates each account for 5%. For defined geometry of microreactor, mass transfer has been determined by carrying out the neutralization experiment with NaOH where acetic acid diffuses from organic phase (hexane) into aqueous phase. Estimated mass transfer coefficients were in the range k{sub L}a=4,652-1,9807 h{sup -1}.

  10. Phototaxis during the slug stage of Dictyostelium discoideum: a model study

    NARCIS (Netherlands)

    Marée, A.F.M.; Panfilov, A.V.; Hogeweg, P.

    1999-01-01

    During the slug stage, the cellular slime mould Dictyostelium discoideum moves towards light sources. We have modelled this phototactic behaviour using a hybrid cellular automata/partial differential equation model. In our model, individual amoebae are not able to measure the direction from which

  11. Ultraviolet Radiation and the Slug Transcription Factor Induce Pro inflammatory and Immunomodulatory Mediator Expression in Melanocytes

    International Nuclear Information System (INIS)

    Shirley, S. H.; Kusewitt, D. F.; Grimm, E. A.

    2012-01-01

    Despite extensive investigation, the precise contribution of the ultraviolet radiation (UVR) component of sunlight to melanoma etiology remains unclear. UVR induces keratinocytes to secrete pro inflammatory and immunomodulatory mediators that promote inflammation and skin tumor development; expression of the slug transcription factor in keratinocytes is required for maximal production of these mediators. In the present studies we examined the possibility that UVR-exposed melanocytes also produce pro inflammatory mediators and that Slug is important in this process. Micro array studies revealed that both UVR exposure and Slug overexpression altered transcription of a variety of pro inflammatory mediators by normal human melanocytes; some of these mediators are also known to stimulate melanocyte growth and migration. There was little overlap in the spectra of cytokines produced by the two stimuli. However IL-20 was similarly induced by both stimuli and the NFκB pathway appeared to be important in both circumstances. Further exploration of UVR-induced and Slug-dependent pathways of cytokine induction in melanocytes may reveal novel targets for melanoma therapy.

  12. Neuropeptides predicted from the transcriptome analysis of the gray garden slug Deroceras reticulatum

    Science.gov (United States)

    The gray garden slug, Deroceras reticulatum (Gastropoda: Pulmonata), is one of the most common terrestrial molluscs. Studies on D. reticulatum have mainly focused on ecology and biology due to severe damages on a wide range of vegetables and field crops. However, little is known about hormonal signa...

  13. FORMING OF MECHANICAL CHARACTERISTICS OF THE SLUGS OF TITANIC ALLOY BT23 AT THERMAL TREATMENT

    Directory of Open Access Journals (Sweden)

    V. N. Fedulov

    2005-01-01

    Full Text Available Тhе changings of the initial plate structure of alloy BT23 at running of high-temperature thermal treatment of large-sized slugs with heating up to 650- 950 eC and cooling on air and in water and their influence on forming of complex of mechanical characteristics are examined.

  14. Mass transfer coefficient of slug flow for organic solvent-aqueous system in a microreactor

    International Nuclear Information System (INIS)

    Tuek, Ana Jurinjak; Anic, Iva; Kurtanjek, Zelimir; Zelic, Bruno

    2015-01-01

    Application of microreactor systems could be the next break-through in the intensification of chemical and biochemical processes. The common flow regime for organic solvent-aqueous phase two-phase systems is a segmented flow. Internal circulations in segments cause high mass transfer and conversion. We analyzed slug flow in seven systems of organic solvents and aqueous phase. To analyze how slug lengths in tested systems depend on linear velocity and physical and chemical properties of used organic solvents, regression models were proposed. It was shown that models based on linearization of approximation by potentials give low correlation for slug length prediction; however, application of an essential nonlinear model of multiple layer perception (MLP) neural network gives high correlation with R 2 =0.9. General sensitivity analysis was applied for the MLP neural network model, which showed that 80% of variance in slug length for the both phases is accounted for the viscosity and density of the organic phases; 10% is accounted by surface tension of the organic phase, while molecular masses and flow rates each account for 5%. For defined geometry of microreactor, mass transfer has been determined by carrying out the neutralization experiment with NaOH where acetic acid diffuses from organic phase (hexane) into aqueous phase. Estimated mass transfer coefficients were in the range k L a=4,652-1,9807 h -1

  15. Thevetia peruviana (Family: Apocynaceae in the control of slug and snail pests

    Directory of Open Access Journals (Sweden)

    A. Panigrahi

    1994-06-01

    Full Text Available An aqueous extract prepared from Kernels of the fruit of Thevetia peruviana (Pers. Schumann (Family : Apocynaceae was found under experimental conditions, to be toxic ti the slug Laevicaulis alte (Férussac and the snail Achatina fulica Bowdich, the important agrihorticultural pests of Indo-Pacific countries. Concentrations as low as 1% (w/v killed all the slugs exposed in less than 981.00 (± SD 22.76 min, and 2% of the extract killed 100% of the slugs L. alte and 50%, 50% and 30% of the snail A. fulica in between 92.34 (± SD 6.63 - 321.33 (± SD 4.14 and 271.20 (± SD 17.54 - 298.26 (± SD 16.69 min respectively. The most effective concentration of the extract was 20%; it killed 100% of exposed slugs and snails within a short time (40-50 and 90-1440 min respectively when the extract was exposed on the soil in experimental trays or when it was applied to potato slices offered as food to the gastropods.

  16. Lactic Acid Extraction and Mass Transfer Characteristics in Slug Flow Capillary Microreactors

    NARCIS (Netherlands)

    Susanti, S.; Winkelman, J.G.N.; Schuur, Boelo; heeres, h.j.; Yue, J.

    2016-01-01

    Capillary microreactors operated under the slug flow regime were investigated for the separation of lactic acid from the aqueous phase using liquid–liquid reactive extraction. The experiments were performed at a 1:1 flow ratio of the aqueous to organic phases in a setup consisting of an inlet Y-type

  17. Experimental investigation and CFD validation of Horizontal Air/Water slug flow

    International Nuclear Information System (INIS)

    Vallee, Christophe; Hoehne, Thomas

    2007-01-01

    For the investigation of co-current two-phase flows at atmospheric pressure and room temperature, the Horizontal Air/Water Channel (HAWAC) was built at Forschungszentrum Dresden-Rossendorf (FZD). At the channel inlet, a special device provides adjustable and well-defined inlet boundary conditions and therefore very good CFD validation possibilities. The HAWAC facility is designed for the application of optical measurement techniques, which deliver the high resolution required for CDF validation. Therefore, the 8 m long acrylic glass test-section with rectangular cross-section provides good observation possibilities. High-speed video observation was applied during slug flow. The camera images show the generation of slug flow from the inlet of the test-section. Parallel to the experiments, CFD calculations were carried out. The aim of the numerical simulations is to validate the prediction of slug flow with the existing multiphase flow models built in the commercial code ANSYS CFX. The Euler-Euler two-fluid model with the free surface option was applied to a grid of 600,000 control volumes. The turbulence was modelled separately for each phase using the k-ω based shear stress transport (SST) turbulence model. The results compare well in terms of slug formation, and breaking. The qualitative agreement between calculation and experiment is encouraging, while quantitative comparison show that further model improvement is needed. (author)

  18. Sensing disks for slug-type calorimeters have higher temperature stability

    Science.gov (United States)

    1967-01-01

    Graphite sensing disk for slug-type radiation calorimeters exhibits better performance at high temperatures than copper and nickel disks. The graphite is heat-soaked to stabilize its emittance and the thermocouple is protected from the graphite so repeated temperature cycling does not change its sensitivity.

  19. Experimental Study of Stable Surfaces for Anti-Slug Control in Multi-phase Flow

    DEFF Research Database (Denmark)

    Pedersen, Simon; Løhndorf, Petar Durdevic; Yang, Zhenyu

    2014-01-01

    -phase flow dynamics, the slug can be avoided or eliminated by proper facility design and control of operational conditions. Based on a testing facility which can emulate a pipeline-riser or a gas-lifted production well in a scaled-down manner, this paper experimentally studies the correlations of key...

  20. Severe slugging in gas-liquid two-phase pipe flow

    NARCIS (Netherlands)

    Malekzadeh, R.

    2012-01-01

    transportation facilities. In an offshore oil and gas production facility, pipeline-riser systems are required to transport two-phase hydrocarbons from subsurface oil and gas wells to a central production platform. Severe slugs reaching several thousands pipe diameters may occur when transporting

  1. Experimental Study of Stable Surfaces for Anti-Slug Control in Multi-phase Flow

    DEFF Research Database (Denmark)

    Pedersen, Simon; Løhndorf, Petar Durdevic; Stampe, Kasper

    2016-01-01

    , the slug can be avoided or eliminated by proper facility design or control of operational conditions. Based on a testing facility which can emulate a pipeline-riser or a gas-lifted production well in a scaled-down manner, this paper experimentally studies the correlations of key operational parameters...

  2. A PLIC-VOF-Based Simulation of Water-Organic Slug Flow Characteristics in a T-Shaped Microchannel

    Directory of Open Access Journals (Sweden)

    Xian Wang

    2013-01-01

    Full Text Available A water-organic slug flow in a T-shaped microchannel was numerically studied due to its importance in the microreactor system. Various factors affecting the flow mode were studied, for example, channel width, fluid viscosity, interfacial tension, and inlet velocity. The volume of fluid (VOF method was used to track the liquid-liquid interface, and the piecewise-liner interface construction (PLIC technique was adopted to get a sharp interface. The interfacial tension was simulated with continuum surface force (CSF, model and the wall adhesion boundary condition was taken into consideration. The results show that strong vortexes appear in both phases at the meeting sites of main and lateral channels where an organic slug is producing. Inlet velocity influences the slug length and flow mode greatly. The ratio between the slug lengths of two phases in the main channel is almost equal to the ratio between their inlet velocities. If the slug is produced, the interfacial tension and organic viscosity have less effect on the slug length for 200 μm microchannel. The slug producing rate is much higher in a narrow channel than that in a wide channel.

  3. Gas6 induces cancer cell migration and epithelial–mesenchymal transition through upregulation of MAPK and Slug

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yunhee [Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of); Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon (Korea, Republic of); Lee, Mira [Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon (Korea, Republic of); Kim, Semi, E-mail: semikim@kribb.re.kr [Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of); Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon (Korea, Republic of)

    2013-04-26

    Highlights: •We investigated the molecular mechanisms underlying Gas6-mediated cancer cell migration. •Gas6 treatment and subsequent Axl activation induce cell migration and EMT via upregulation of Slug. •Slug expression mediated by Gas6 is mainly through c-Jun and ATF-2 in an ERK1/2 and JNK-dependent manner. •The Gas6/Axl-Slug axis may be exploited as a target for anti-cancer metastasis therapy. -- Abstract: Binding of Gas6 to Axl (Gas6/Axl axis) alters cellular functions, including migration, invasion, proliferation, and survival. However, the molecular mechanisms underlying Gas6-mediated cell migration remain poorly understood. In this study, we found that Gas6 induced the activation of JNK and ERK1/2 signaling in cancer cells expressing Axl, resulting in the phosphorylation of activator protein-1 (AP-1) transcription factors c-Jun and ATF-2, and induction of Slug. Depletion of c-Jun or ATF-2 by siRNA attenuated the Gas6-induced expression of Slug. Slug expression was required for cell migration and E-cadherin reduction/vimentin induction induced by Gas6. These results suggest that Gas6 induced cell migration via Slug upregulation in JNK- and ERK1/2-dependent mechanisms. These data provide an important insight into the molecular mechanisms mediating Gas6-induced cell migration.

  4. Application of Ceramic Bond Coating for Reusable Melting Crucible of Metallic Fuel Slugs

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ki-Hwan; Song, Hoon; Ko, Young-Mo; Park, Jeong-Yong; Lee, Chan-Bock [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Hong, Ki-Won [Chungnam National University, Daejeon (Korea, Republic of)

    2016-10-15

    Metal fuel slugs of the driver fuel assembly have been fabricated by injection casting of the fuel alloys under a vacuum state or an inert atmosphere. Traditionally, metal fuel such as a U-Zr alloy system for SFR has been melted in slurry-coated graphite crucibles and cast in slurry-coated quartz tube molds to prevent melt/material interactions. Reactive coatings and porous coatings can be a source of melt contaminations, and fuel losses, respectively. Ceramic Y{sub 2}O{sub 3}, TiC, and TaC coating materials showed no penetration in the protective layer after a melt dipping test. However, the ceramic coating materials showed separations in the coating interface between the substrate and coating layer, or between the coating layer and fuel melt after the dipping test. All plasma-spray coated methods maintained a sound coating state after a dipping test with U-10wt.%Zr melt. A single coating Y{sub 2}O{sub 3}(150) layer and double coating layer of TaC(50)-Y{sub 2}O{sub 3}(100), showed a sound state or little penetration in the protective layer after a dipping test with U-10wt.%Zr-5wt.%RE melt. Injection casting experiments of U-10wt.%Zr and U-10wt.%Zr-5wt.%RE fuel slugs have been performed to investigate the feasibility of a reusable crucible of the metal fuel slugs. U–10wt.%Zr and U–10wt.%Zr–5wt.%RE fuel slugs have been soundly fabricated without significant interactions of the graphite crucibles. Thus, the ceramic plasma-spray coatings are thought to be promising candidate coating methods for a reusable graphite crucible to fabricate metal fuel slugs.

  5. Evaluation of the effects of the radial constant-head boundary in slug tests

    Science.gov (United States)

    Dai, Yunfeng; Zhou, Zhifang; Zhao, Yanrong; Cui, Ziteng

    2015-03-01

    A semianalytical model of slug tests, conducted in a completely penetrating well within a radial constant-head boundary, was derived. The model, based on the Cooper et al. (1967) model, estimates the hydraulic conductivity and storage coefficient through the matching of type curves. Type curves of the semianalytical solution were plotted, and the effect of the distance of the radial constant-head boundary is discussed. For different storage coefficients, the critical distances of the effect of the constant-head boundary were determined. The effect of the storage coefficient on the response of the water head in slug tests with a radial constant-head boundary of a certain distance is also shown. To verify the model, laboratory slug-test experiments were carried out using a cylindrical test platform, in which an artificial confined coarse-sand aquifer was built. Pumping tests were also executed using the test platform. The Cooper et al. (1967) model and new semianalytical model were used to analyze measurements; the hydraulic conductivity and storage coefficient determined using the two methods were compared to demonstrate the importance of the radial constant-head boundary. A model considering the inertial effect was also used to analyze the slug-test measurements, and although the water head response did not oscillate greatly, the inertial effect affected the slug-test calculation result. The laboratory experiments indicate that the proposed semianalytical model is reasonable and reliable. Cooper HH, Bredehoeft JD, Papadopulos IS (1967) Response of a finite-diameter well to an instantaneous charge of water, Water Resour Res 3(1):263-269.

  6. The parasitic nematode Phasmorhabditis hermaphrodita defends its slug host from being predated or scavenged by manipulating host spatial behaviour

    Czech Academy of Sciences Publication Activity Database

    Pechová, H.; Foltan, Pavel

    2008-01-01

    Roč. 78, č. 3 (2008), s. 416-420 ISSN 0376-6357 Institutional research plan: CEZ:AV0Z50070508 Keywords : manipulation * slug * nematode Subject RIV: EH - Ecology, Behaviour Impact factor: 1.441, year: 2008

  7. Combination of rapamycin, CI-1040, and 17-AAG inhibits metastatic capacity of prostate cancer via Slug inhibition.

    Directory of Open Access Journals (Sweden)

    Guanxiong Ding

    Full Text Available Though prostate cancer (PCa has slow progression, the hormone refractory (HRCP and metastatic entities are substantially lethal and lack effective treatments. Transcription factor Slug is critical in regulating metastases of various tumors including PCa. Here we studied targeted therapy against Slug using combination of 3 drugs targeting 3 pathways respectively converging via Slug and further regulating PCa metastasis. Using in vitro assays we confirmed that Slug up-regulation incurred inhibition of E-cadherin that was anti-metastatic, and inhibited Bim-regulated cell apoptosis in PCa. Upstream PTEN/Akt, mTOR, Erk, and AR/Hsp90 pathways were responsible for Slug up-regulation and each of these could be targeted by rapamycin, CI-1040, and 17-AAG respectively. In 4 PCa cell lines with different traits in terms of PTEN loss and androgen sensitivity we tested the efficacy of mono- and combined therapy with the drugs. We found that metastatic capacity of the cells was maximally inhibited only when all 3 drugs were combined, due to the crosstalk between the pathways. 17-AAG decreases Slug expression via blockade of HSP90-dependent AR stability. Combination of rapamycin and CI-1040 diminishes invasiveness more potently in PCa cells that are androgen insensitive and with PTEN loss. Slug inhibited Bim-mediated apoptosis that could be rescued by mTOR/Erk/HSP90 inhibitors. Using mouse models for circulating PCa DNA quantification, we found that combination of mTOR/Erk/HSP90 inhibitors reduced circulating PCa cells in vivo significantly more potently than combination of 2 or monotherapy. Conclusively, combination of mTOR/Erk/Hsp90 inhibits metastatic capacity of prostate cancer via Slug inhibition.

  8. miR-34 increases in vitro PANC-1 cell sensitivity to gemcitabine via targeting Slug/PUMA.

    Science.gov (United States)

    Zhang, Qing-An; Yang, Xu-Hai; Chen, Dong; Yan, Xiang; Jing, Fu-Chun; Liu, Hong-Qian; Zhang, Ronghua

    2018-01-01

    miR-34 was deregulated in tumor tissues compared with corresponding noncancerous tissue samples. Furthermore, miR-34 may contribute to cancer-stromal interaction associated with cancer progression. However, whether miR-34 could decrease chemoresistance of cancer cells to chemotherapeutic agent remains unclear. In our study, we examined whether overexpression of miR-34 could sensitize gemcitabine -mediated apoptosis in human pancreatic cancer PANC-1 cells. We found that miR-34 markedly induced gemcitabine -mediated apoptosis in PANC-1 cells. miR-34 induced down-regulation of Slug expression and upregulation of p53 up-regulated modulator of apoptosis (PUMA) expression. The over-expression of Slug or downregulation of PUMA by Slug cDNA or PUMA siRNA transfection markedly blocked miR-34-induced gemcitabine sensitization. Furthermore, miR-34 induced PUMA expression by downregulation of Slug. Taken together, our study demonstrates that miR-34 enhances sensitization against gemcitabine-mediated apoptosis through the down-regulation of Slug expression, and up-regulation of Slug-dependent PUMA expression.

  9. Antifeedant compounds from three species of Apiaceae active against the field slug, Deroceras reticulatum (Muller).

    Science.gov (United States)

    Birkett, Michael A; Dodds, Catherine J; Henderson, Ian F; Leake, Lucy D; Pickett, John A; Selby, Martin J; Watson, Peter

    2004-03-01

    Extracts of volatiles from foliage of three plants in the Apiaceae, Conium maculatum L. (hemlock), Coriandrum sativum L. (coriander), and Petroselinum crispum Mill. (Nym.) (parsley), previously shown to exhibit antifeedant activity in assays with the field slug, Deroceras reticulatum (Muller) (Limacidae: Pulmonata), were studied further to identify the active components. Coupled gas chromatography-mass spectrometry (GC-MS) and neurophysiological assays using tentacle nerve preparations resulted in the identification of 11 active compounds from the three extracts. Wheat flour feeding bioassays were used to determine which of these compounds had the highest antifeedant activity. One of the most active compounds was the alkaloid gamma-coniceine, from C. maculatum. The role of potentially toxic alkaloids as semiochemicals and the potential for using such compounds as crop protection agents to prevent slug feeding damage is discussed.

  10. The analysis of fuel constituent redistribution for ternary metallic fuel slug

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byoung Oon; Lee, Dong Uk; Kim, Young Kyun; Chang, Jin Wook; Lee, Ki Bok; Kim, Young Il

    2004-02-01

    U-TRU-Zr metallic alloy is being considered as the fuel slug for the proliferation resistance core of KALIMER. The radial fuel constituent migration is a general phenomenon in the metallic alloys. This phenomenon may affect the in-reactor performance of metallic fuel rods, influencing such factors as melting temperature, thermal conductivity, power generation rate, phase boundaries and eutectic melting of the fuel slug. Thus, constituent redistribution modeling is essential when developing a metallic fuel performance code. The constituent migration model adopted in this report was based on the Ishida's model and Hofman's theory. A subroutine program has been made and installed into the MACSIS code to simulate constituent redistribution. The radial profile of Zr redistribution was calculated for the ternary metallic fuel, and compared with the measured data.

  11. The use of a low-cost gas-liquid flow meter to monitor severe slugging

    DEFF Research Database (Denmark)

    Andreussi, Paolo; Bonizzi, Marco; Ciandri, Paolo

    2017-01-01

    A very simple, low-cost gas-liquid flow meter that only employs conventional field instrumentation has been used to monitor severe slugging occurring at the exit of a vertical pipe. This meter was originally developed for conventional oil field applications [1] and is based on the readings...... method to monitor severe slugging by means of low cost instrumentation, in particular, by replacing a cumbersome instrument such as a gamma-densitometer with a differential pressure transmitter. In field operation, the multiphase orifice used in these experiments can be replaced by a calibrated control...... of a multiphase orifice and the pressure drops of the gas-liquid mixture flowing in a vertical section of the pipe. Liquid and gas flow rates have been determined by means of semi-empirical equations developed for the specific set of flow parameters (geometry, flow rates, physical properties) adopted in a series...

  12. A criterion for the onset of slugging in horizontal stratified air-water countercurrent flow

    International Nuclear Information System (INIS)

    Chun, Moon-Hyun; Lee, Byung-Ryung; Kim, Yang-Seok

    1995-01-01

    This paper presents an experimental and theoretical investigation of wave height and transition criterion from wavy to slug flow in horizontal air-water countercurrent stratified flow conditions. A theoretical formula for the wave height in a stratified wavy flow regime has been developed using the concept of total energy balance over a wave crest to consider the shear stress acting on the interface of two fluids. From the limiting condition of the formula for the wave height, a necessary criterion for transition from a stratified wavy flow to a slug flow has been derived. A series of experiments have been conducted changing the non-dimensional water depth and the flow rates of air in a horizontal pipe and a duct. Comparisons between the measured data and the predictions of the present theory show that the agreement is within ±8%

  13. A criterion for the onset of slugging in horizontal stratified air-water countercurrent flow

    Energy Technology Data Exchange (ETDEWEB)

    Chun, Moon-Hyun; Lee, Byung-Ryung; Kim, Yang-Seok [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of)] [and others

    1995-09-01

    This paper presents an experimental and theoretical investigation of wave height and transition criterion from wavy to slug flow in horizontal air-water countercurrent stratified flow conditions. A theoretical formula for the wave height in a stratified wavy flow regime has been developed using the concept of total energy balance over a wave crest to consider the shear stress acting on the interface of two fluids. From the limiting condition of the formula for the wave height, a necessary criterion for transition from a stratified wavy flow to a slug flow has been derived. A series of experiments have been conducted changing the non-dimensional water depth and the flow rates of air in a horizontal pipe and a duct. Comparisons between the measured data and the predictions of the present theory show that the agreement is within {plus_minus}8%.

  14. Slug-annular transition with particular reference to narrow rectangular ducts

    International Nuclear Information System (INIS)

    Jones, O.C. Jr.; Zuber, N.

    1978-01-01

    The transition from slug-flow to annular-flow in two-phase, gas-liquid mixtures is analyzed. A transition equation is derived which agrees well when compared with objective data determined from the disappearance of the low-void peak in the void fluctuation probability density in a rectangular duct. Application to other geometries is suggested and tabular recommendations given for determination of the drift flux coefficient, K, based on results in the literature

  15. Flow measurement in bubbly and slug flow regimes using the electromagnetic flowmeter developed

    International Nuclear Information System (INIS)

    Cha, Jae Eun; Ahn, Yeh Chan; Seo, Kyung Woo; Kim, Moo Hwan

    2002-01-01

    In order to investigate the characteristics of electromagnetic flowmeter in two-phase flow, an AC electromagnetic flowmeter was designed and manufactured. In various flow conditions, the signals and noises from the flowmeter were obtained and analyzed by comparison with the observed flow patterns with a high speed CCD camera. The experiment with the void simulators in which rod shaped non-conducting material was used was carried out to investigate the effect of the bubble position and the void fraction on the flowmeter. Based on the results from the void simulator, two-phase flow experiments encompassed from bubbly to slug flow regime were conducted. The simple relation ΔU TP = ΔU SP /(1-α) was verified with measurements of the potential difference and the void fraction. Due to the lack of homogeneity in a real two-phase flow, the discrepancy between the relation and the present measurement was slightly increased with void fraction and also liquid volumetric flux j f . Whereas there is no difference in the shape of the raw signal between single-phase flow and bubbly flow, the signal amplitude for bubbly flow is higher than that for single-phase flow at the same water flow rate, since the passage area of the water flow is reduced. In the case of slug flow, the phase and the amplitude of the flowmeter output show dramatically the flow characteristics around each slug bubble and the position of a slug bubble itself. Therefore, the electromagnetic flowmeter shows a good possibility of being useful for identifying the flow regimes

  16. Fluidization behavior in a circulating slugging fluidized bed reactor. Part II: Plug characteristics

    NARCIS (Netherlands)

    van Putten, I.C.; van Sint Annaland, M.; Weickert, G.

    2007-01-01

    In the transporting square nosed slugging fluidization regime (0.4 < u0 < 1.0m/s) a bed of polyethylene powder with a low density (ρ = 900/kg/m3) and a large particle size distribution (70 < dρ < 1600µm) was operated in two circulating fluidized bed systems (riser diameters 0.044 and 0.105 m). A

  17. EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer

    International Nuclear Information System (INIS)

    Haslehurst, Alexandria M; Weberpals, Johanne; Davey, Scott; Squire, Jeremy; Park, Paul C; Feilotter, Harriet; Koti, Madhuri; Dharsee, Moyez; Nuin, Paulo; Evans, Ken; Geraci, Joseph; Childs, Timothy; Chen, Jian; Li, Jieran

    2012-01-01

    The epithelial to mesenchymal transition (EMT) is a molecular process through which an epithelial cell undergoes transdifferentiation into a mesenchymal phenotype. The role of EMT in embryogenesis is well-characterized and increasing evidence suggests that elements of the transition may be important in other processes, including metastasis and drug resistance in various different cancers. Agilent 4 × 44 K whole human genome arrays and selected reaction monitoring mass spectrometry were used to investigate mRNA and protein expression in A2780 cisplatin sensitive and resistant cell lines. Invasion and migration were assessed using Boyden chamber assays. Gene knockdown of snail and slug was done using targeted siRNA. Clinical relevance of the EMT pathway was assessed in a cohort of primary ovarian tumours using data from Affymetrix GeneChip Human Genome U133 plus 2.0 arrays. Morphological and phenotypic hallmarks of EMT were identified in the chemoresistant cells. Subsequent gene expression profiling revealed upregulation of EMT-related transcription factors including snail, slug, twist2 and zeb2. Proteomic analysis demonstrated up regulation of Snail and Slug as well as the mesenchymal marker Vimentin, and down regulation of E-cadherin, an epithelial marker. By reducing expression of snail and slug, the mesenchymal phenotype was largely reversed and cells were resensitized to cisplatin. Finally, gene expression data from primary tumours mirrored the finding that an EMT-like pathway is activated in resistant tumours relative to sensitive tumours, suggesting that the involvement of this transition may not be limited to in vitro drug effects. This work strongly suggests that genes associated with EMT may play a significant role in cisplatin resistance in ovarian cancer, therefore potentially leading to the development of predictive biomarkers of drug response or novel therapeutic strategies for overcoming drug resistance

  18. EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer

    Directory of Open Access Journals (Sweden)

    Haslehurst Alexandria M

    2012-03-01

    Full Text Available Abstract Background The epithelial to mesenchymal transition (EMT is a molecular process through which an epithelial cell undergoes transdifferentiation into a mesenchymal phenotype. The role of EMT in embryogenesis is well-characterized and increasing evidence suggests that elements of the transition may be important in other processes, including metastasis and drug resistance in various different cancers. Methods Agilent 4 × 44 K whole human genome arrays and selected reaction monitoring mass spectrometry were used to investigate mRNA and protein expression in A2780 cisplatin sensitive and resistant cell lines. Invasion and migration were assessed using Boyden chamber assays. Gene knockdown of snail and slug was done using targeted siRNA. Clinical relevance of the EMT pathway was assessed in a cohort of primary ovarian tumours using data from Affymetrix GeneChip Human Genome U133 plus 2.0 arrays. Results Morphological and phenotypic hallmarks of EMT were identified in the chemoresistant cells. Subsequent gene expression profiling revealed upregulation of EMT-related transcription factors including snail, slug, twist2 and zeb2. Proteomic analysis demonstrated up regulation of Snail and Slug as well as the mesenchymal marker Vimentin, and down regulation of E-cadherin, an epithelial marker. By reducing expression of snail and slug, the mesenchymal phenotype was largely reversed and cells were resensitized to cisplatin. Finally, gene expression data from primary tumours mirrored the finding that an EMT-like pathway is activated in resistant tumours relative to sensitive tumours, suggesting that the involvement of this transition may not be limited to in vitro drug effects. Conclusions This work strongly suggests that genes associated with EMT may play a significant role in cisplatin resistance in ovarian cancer, therefore potentially leading to the development of predictive biomarkers of drug response or novel therapeutic strategies for

  19. Flow near the meniscus of a pressure-driven water slug in microchannels

    International Nuclear Information System (INIS)

    Kim, Sung Wook; Jin, Song Wan; Yoo, Jung Yul

    2006-01-01

    Micro-PIV system with a high speed CCD camera is used to measure the flow field near the advancing meniscus of a water slug in microchannels. Image shifting technique combined with meniscus detecting technique is proposed to measure the relative velocity of the liquid near the meniscus in a moving reference frame. The proposed method is applied to an advancing front of a slug in microchannels with rectangular cross section. In the case of hydrophilic channel, strong flow from the center to the side wall along the meniscus occurs, while in the case of the hydrophobic channel, the fluid flows in the opposite direction. Further, the velocity near the side wall is higher than the center region velocity, exhibiting the characteristics of a strong shear-driven flow. This phenomenon is explained to be due to the existence of small gaps between the slug and the channel wall at each capillary corner so that the gas flows through the gaps inducing high shear on the slug surface. Simulation of the shape of a static droplet inside a cubic cell obtained by using the Surface Evolver program is supportive of the existence of the gap at the rectangular capillary corners. The flow fields in the circular capillary, in which no such gap exists, are also measured. The results show that a similar flow pattern to that of the hydrophilic rectangular capillary (i.e., center-to-wall flow) is always exhibited regardless of the wettability of the channel wall, which is also indicative of the validity of the above-mentioned assertion

  20. A sea slug’s guide to plastid symbiosis

    Directory of Open Access Journals (Sweden)

    Jan de Vries

    2014-12-01

    Full Text Available Some 140 years ago sea slugs that contained chlorophyll-pigmented granules similar to those of plants were described. While we now understand that these “green granules” are plastids the slugs sequester from siphonaceous algae upon which they feed, surprisingly little is really known about the molecular details that underlie this one of a kind animal-plastid symbiosis. Kleptoplasts are stored in the cytosol of epithelial cells that form the slug’s digestive tubules, and one would guess that the stolen organelles are acquired for their ability to fix carbon, but studies have never really been able to prove that. We also do not know how the organelles are distinguished from the remaining food particles the slugs incorporate with their meal and that include algal mitochondria and nuclei. We know that the ability to store kleptoplasts long-term has evolved only a few times independently among hundreds of sacoglossan species, but we have no idea on what basis. Here we take a closer look at the history of sacoglossan research and discuss recent developments. We argue that, in order to understand what makes this symbiosis work, we will need to focus on the animal’s physiology just as much as we need to commence a detailed analysis of the plastids’ photobiology. Understanding kleptoplasty in sacoglossan slugs requires an unbiased multidisciplinary approach.

  1. Lava Fountaining Discharge Regime driven by Slug-to-Churn Flow Transition. (Invited)

    Science.gov (United States)

    Ripepe, M.; Pioli, L.; Marchetti, E.; Ulivieri, G.

    2013-12-01

    Lava fountaining episodes at Etna volcano appear characterized by the transition between Strombolian and Hawaiian end-member eruptive styles. There is no evidence for this transition in the seismic (i.e. seismic tremor) signal. However, infrasonic records provide unprecedented evidence on this flow transition. Each eruptive episode is characterized by distinctive common trend in the amplitude, waveform and frequency content of the infrasonic wavefield, which evidences the shift from discrete, and transient, strombolian to sustained, and oscillatory, lava fountain dynamics. Large scale experiments on the dynamics of two-phase flow of basaltic magmas show how the transition between different regimes mainly depends on gas volume flow, which in turn controls pressure distribution within the conduit and also magma vesicularity. In particular, while regular large bubble bursting is associated with slug flow regime, large amplitude and low frequency column oscillations are associated with churn flow. In large pipes, transition from slug to churn flow regime is independent on conduit diameter and it is reached at high superficial gas velocity. Lava fountaining episodes at Etna can be thus interpreted as induced by the transition from the slug (discrete strombolian) to churn flow (sustained lava fountain) regimes that is reflecting an increase in the gas discharge rate. Based on laboratory experiments, we calculate that transition between these two end-member explosive regimes at Etna occurs when gas superficial velocity is 76 m/s for near-the-vent stagnant magma conditions.

  2. Health physics monitoring during cobalt slug rod handling at research reactor Dhruva: an experience

    International Nuclear Information System (INIS)

    Verma, Gopal P.; Bhatnagar, Amit; Krishnamohanan, T.; Kalyanasundaram, N.; Gupta, P.C.; Pushparaja; Ghosh, Runner

    2006-01-01

    Cobalt-60 is used in many industrial and medical applications, such as leveling devices, thickness gauge, sterilization of foodstuff to increase their shelf life, sterilization of medicines and in radiotherapy. The Cobalt slug rod containing cobalt pencils were irradiated for nearly two and half years in the Dhruva reactor core to obtain the 60 Co isotope. It had seen a total irradiation of 29053 MWD and the estimated total activity was 93.321 KCi. Campaign for the removal of irradiated rod from reactor core and retrieval of 60 Co pencils were carried out successfully in Dhruva Reactor complex. In view of such a high activity handled, the job was carried out after exhaustive prior planning and according to approved checklists. Radiation Hazards Control Unit, Dhruva provided Radiation Safety surveillance during the entire handling operation consisting of retrieval of the cobalt pencils and disposal of the aluminum slugs used to house the cobalt pencils in the Cobalt slug rod assembly. The whole operation was carried out in such a safe manner that the total man-rem consumption was insignificant. The operational radiation protection methods followed and the experience gained during the campaign are discussed in this paper. (author)

  3. Interfacial area, velocity and void fraction in two-phase slug flow

    International Nuclear Information System (INIS)

    Kojasoy, G.; Riznic, J.R.

    1997-01-01

    The internal flow structure of air-water plug/slug flow in a 50.3 mm dia transparent pipeline has been experimentally investigated by using a four-sensor resistivity probe. Liquid and gas volumetric superficial velocities ranged from 0.55 to 2.20 m/s and 0.27 to 2.20 m/s, respectively, and area-averaged void fractions ranged from about 10 to 70%. The local distributions of void fractions, interfacial area concentration and interface velocity were measured. Contributions from small spherical bubbles and large elongated slug bubbles toward the total void fraction and interfacial area concentration were differentiated. It was observed that the small bubble void contribution to the overall void fraction was small indicating that the large slug bubble void fraction was a dominant factor in determining the total void fraction. However, the small bubble interfacial area contribution was significant in the lower and upper portions of the pipe cross sections

  4. Fabrication of uranium alloy fuel slug for sodium-cooled fast reactor by injection casting

    International Nuclear Information System (INIS)

    Jong Hwan Kim; Hoon Song; Ki Hwan Kim; Chan Bock Lee

    2014-01-01

    Metal fuel slugs of U-Zr alloys for a sodium-cooled fast reactor (SFR) have been fabricated using an injection casting method. However, casting alloys containing volatile radioactive constituents such as Am can cause problems in a conventional injection casting method. Therefore, in this study, several injection-casting methods were applied to evaluate the volatility of the metal-fuel elements and control the transport of volatile elements. Mn was selected as a volatile surrogate alloy since it possesses a total vapor pressure equivalent to that of minor actinide-bearing fuels for SFRs. U-10 wt% Zr and U-10 wt% Zr-5 wt% Mn metal fuels were prepared, and the casting processes were evaluated. The casting soundness of the fuel slugs was characterized by gamma-ray radiography and immersion density measurements. Inductively coupled plasma atomic emission spectroscopy was used to determine the chemical composition of fuel slugs. Fuel losses after casting were also evaluated according to the casting conditions. (author)

  5. Transmissivity and storage coefficient estimates from slug tests, Naval Air Warfare Center, West Trenton, New Jersey

    Science.gov (United States)

    Fiore, Alex R.

    2014-01-01

    Slug tests were conducted on 56 observation wells open to bedrock at the former Naval Air Warfare Center (NAWC) in West Trenton, New Jersey. Aquifer transmissivity (T) and storage coefficient (S) values for most wells were estimated from slug-test data using the Cooper-Bredehoeft-Papadopulos method. Test data from three wells exhibited fast, underdamped water-level responses and were analyzed with the Butler high-K method. The range of T at NAWC was approximately 0.07 to 10,000 square feet per day. At 11 wells, water levels did not change measurably after 20 minutes following slug insertion; transmissivity at these 11 wells was estimated to be less than 0.07 square feet per day. The range of S was approximately 10-10 to 0.01, the mode being 10-10. Water-level responses for tests at three wells fit poorly to the type curves of both methods, indicating that these methods were not appropriate for adequately estimating T and S from those data.

  6. Effects of Agroecological and Conventional Handling in Slug Populations in Lettuce in Tenjo, Cundinamarca (Colombia)

    International Nuclear Information System (INIS)

    Cordoba Vargas, Cindy Alexandra; Leon Sicard, Tomas

    2010-01-01

    In an organic (FE) and a conventional (FC) farm system the population behavior of slugs and their relationship with some carabids predators was compared, as well as, the presence of weeds, agricultural practices and productivity of four varieties of lettuce. Weekly catches of slugs were made and the damage level, height and the number of leaves in ten plants was measured. Weeds and carabids were collected in both farms. The total number of slugs in the FE was statistically higher and four species (D. reticulatum, Milax gagates, D. and L. laev maximux) were collected compared with two found in FC. With the exception of the variety M orada Lisa , there were no significant differences in the level of damage in the other varieties between the two farms. There were significant differences in the dry weight variable in favour of the organic farm. In FE, 5 carabids species and 25 weeds were presented compared to none in FC and 6, respectively. The data above are explained in terms of the agronomic practices of each management system.

  7. Prediction of Polymer Flooding Performance with an Artificial Neural Network: A Two-Polymer-Slug Case

    Directory of Open Access Journals (Sweden)

    Jestril Ebaga-Ololo

    2017-07-01

    Full Text Available Many previous contributions to methods of forecasting the performance of polymer flooding using artificial neural networks (ANNs have been made by numerous researchers previously. In most of those forecasting cases, only a single polymer slug was employed to meet the objective of the study. The intent of this manuscript is to propose an efficient recovery factor prediction tool at different injection stages of two polymer slugs during polymer flooding using an ANN. In this regard, a back-propagation algorithm was coupled with six input parameters to predict three output parameters via a hidden layer composed of 10 neurons. Evaluation of the ANN model performance was made with multiple linear regression. With an acceptable correlation coefficient, the proposed ANN tool was able to predict the recovery factor with errors of <1%. In addition, to understand the influence of each parameter on the output parameters, a sensitivity analysis was applied to the input parameters. The results showed less impact from the second polymer concentration, owing to changes in permeability after the injection of the first polymer slug.

  8. Correlation of Slug gene expression with lymph node metastasis and invasion molecule expression in oral squamous cell carcinoma tissue

    Directory of Open Access Journals (Sweden)

    Shan-Ming Lu

    2017-10-01

    Full Text Available Objective: To study the correlation of Slug gene expression with lymph node metastasis and invasion molecule expression in oral squamous cell carcinoma tissue. Methods: Oral squamous cell carcinoma tissue surgical removed in Affiliated Stomatological Hospital of Nanjing Medical University between March 2015 and April 2017 was selected and divided into the oral squamous cell carcinoma tissue with neck lymph node metastasis and the oral squamous cell carcinoma tissues without lymph node metastasis according to the condition of lymph node metastasis. The expression of Slug, epithelial-mesenchymal transition molecules and invasion molecules in the oral squamous cell carcinoma tissue were detected. Results: Slug, N-cadherin, Vimentin, CD147, OPN, GRP78, SDF-1 and CXCR4 protein expression in oral squamous cell carcinoma tissue with neck lymph node metastasis were significantly higher than those in oral squamous cell carcinoma tissue without lymph node metastasis while E-cadherin, P120ctn and ZO-1 protein expression were significantly lower than those in oral squamous cell carcinoma tissue without lymph node metastasis; N-cadherin, Vimentin, CD147, OPN, GRP78, SDF-1 and CXCR4 protein expression in oral squamous cell carcinoma tissue with high Slug expression were significantly higher than those in oral squamous cell carcinoma tissue with low Slug expression while E-cadherin, P120ctn and ZO-1 protein expression were significantly lower than those in oral squamous cell carcinoma tissue with low Slug expression. Conclusion: The highly expressed Slug in oral squamous cell carcinoma tissue can promote the epithelial-mesenchymal transition and invasion of the cells to participate in the lymph node metastasis of tumor cells.

  9. ΔNp63α induces the expression of FAT2 and Slug to promote tumor invasion

    Science.gov (United States)

    Dang, Tuyen T.; Westcott, Jill M.; Maine, Erin A.; Kanchwala, Mohammed; Xing, Chao; Pearson, Gray W.

    2016-01-01

    Tumor invasion can be induced by changes in gene expression that alter cell phenotype. The transcription factor ΔNp63α promotes basal-like breast cancer (BLBC) migration by inducing the expression of the mesenchymal genes Slug and Axl, which confers cells with a hybrid epithelial/mesenchymal state. However, the extent of the ΔNp63α regulated genes that support invasive behavior is not known. Here, using gene expression analysis, ChIP-seq, and functional testing, we find that ΔNp63α promotes BLBC motility by inducing the expression of the atypical cadherin FAT2, the vesicular binding protein SNCA, the carbonic anhydrase CA12, the lipid binding protein CPNE8 and the kinase NEK1, along with Slug and Axl. Notably, lung squamous cell carcinoma migration also required ΔNp63α dependent FAT2 and Slug expression, demonstrating that ΔNp63α promotes migration in multiple tumor types by inducing mesenchymal and non-mesenchymal genes. ΔNp63α activation of FAT2 and Slug influenced E-cadherin localization to cell-cell contacts, which can restrict spontaneous cell movement. Moreover, live-imaging of spheroids in organotypic culture demonstrated that ΔNp63α, FAT2 and Slug were essential for the extension of cellular protrusions that initiate collective invasion. Importantly, ΔNp63α is co-expressed with FAT2 and Slug in patient tumors and the elevated expression of ΔNp63α, FAT2 and Slug correlated with poor patient outcome. Together, these results reveal how ΔNp63α promotes cell migration by directly inducing the expression of a cohort of genes with distinct cellular functions and suggest that FAT2 is a new regulator of collective invasion that may influence patient outcome. PMID:27081041

  10. Off-take and slug transition at T-junction of vertical-up branch in the horizontal pipe

    International Nuclear Information System (INIS)

    Moon, Young Min; No, Hee Cheon

    2003-01-01

    The off-take and the slug transition on air-water interface are experimentally investigated at the T-junction of the horizontal pipe with a vertical upward branch to simulate the loss-of-residual-heat-removal during a mid-loop operation in the Korea standard nuclear power plant. Scaling analysis is performed to scale down the experimental facility to the reference nuclear power plant. Two different diameters of branch pipes are used to verify the scaling laws and their scale effects. Air is used as working gaseous fluid and no water flow exists. Off-take behavior on horizontal stratified and slug flows is visually observed in the horizontal pipe. The experimental data are divided into three categories; onset of liquid entrainment at T-junctions, onset of slug transition in the horizontal pipe, and discharge quality in the branch pipe. It is found out that the scale effect of the branch diameter on the onset of liquid entrainment is small and the existing correlations for it are applicable. Also, the onset of slug transition shows a discrepancy with Taitel-Dukler's correlation and has a strong influence on the discharge quality. New correlations for discharge quality are developed considering the critical dependency of the onset of slugging. (author)

  11. MULTIPHASE DROPLET/SLUG BREAK-UP MECHANISM IN MICROFLUIDIC T-JUNCTIONS AT VARIOUS WEBER NUMBERS

    Directory of Open Access Journals (Sweden)

    Wan Leng (Dawn Leow

    2011-10-01

    Full Text Available Normal 0 false false false EN-MY X-NONE X-NONE The formation of immiscible liquid droplets, or slugs, in microchannels features the advantages of volume control and mixing enhancement over single-phase microflows. Although the applications of droplet-based microfluidics have been widely demonstrated, the fundamental physics governing droplet break-up remains an area of active research. This study defines an effective Weber (Weeff number that characterizes the interplay of interfacial tension, shear stress and channel pressure drop in driving slug formation in T-junction microchannel for a relative range of low, intermediate and high flow rates. The immiscible fluid system in this study consists of Tetradecane slug formation in Acetonitrile. The progressive deformation of slug interfaces during break-up events is observed. Experimental results indicate that, at a relatively low Weeff, clean slug break-up occurs at the intersection of the side and main channels. At intermediate Weeff, the connecting neck of the dispersed phase is stretched to a short and thin trail of laminar flow prior to breaking up a short distance downstream of the T-junction. At a relatively high Weeff, the connecting neck develops into a longer and thicker trail of laminar flow that breaks up further downstream of the main channel.

  12. Fabrication of U-10wt.%Zr Fuel slug for SFR by Injection Casting

    International Nuclear Information System (INIS)

    Kim, Jong Hwan; Song, Hoon; Kim, Hyung Tae; Ko, Young Mo; Kim, Ki Hwan; Lee, Chan B.

    2013-01-01

    The fabrication technology of metal fuel has been developed by various methods such as rolling, swaging, wire drawing, and co-extrusion, but each of these methods had process limitations requiring an additional subsequent process, and needing the fabrication equipment is complex, which is not favorable for remote use. A practical process of metallic fuel fabrication for an SFR needs to be cost efficient, suitable for remote operation, and capable of mass production while reducing the amount of radioactive waste. Injection casting was chosen as the most promising technique, in the early 1950s, and this technique has been applied to fuel slug fabrication for the Experimental Breeder Reactor-II (EBR-II) driver and the Fast Flux Test Facility (FFTF) fuel pins. Because of the simplistic nature of the process and equipment, compared to other processes examined, this process has been successfully used in a remote operation environment for fueling of the EBR-II reactor. In this study, vacuum injection casting suitable for remote operation has been developed to fabricate metallic fuel for an SFR. Vacuum injection casting technique was developed to fabricate metallic fuel for an SFR. The appearance of the fabricated U-10wt.%Zr fuel was generally sound and the internal integrity was found to be satisfactory through gamma-ray radiography. Minimum fuel losses after casting relative to the initial charge amount of U-10wt.%Zr fuel slugs met the proposed goal of less than 0.1% fuel losses during fabrication. Modifications of the current facility system and advanced casting techniques are underway to produce higher quality fuel slugs

  13. Fabrication of U-10wt.%Zr Fuel slug for SFR by Injection Casting

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jong Hwan; Song, Hoon; Kim, Hyung Tae; Ko, Young Mo; Kim, Ki Hwan; Lee, Chan B. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-10-15

    The fabrication technology of metal fuel has been developed by various methods such as rolling, swaging, wire drawing, and co-extrusion, but each of these methods had process limitations requiring an additional subsequent process, and needing the fabrication equipment is complex, which is not favorable for remote use. A practical process of metallic fuel fabrication for an SFR needs to be cost efficient, suitable for remote operation, and capable of mass production while reducing the amount of radioactive waste. Injection casting was chosen as the most promising technique, in the early 1950s, and this technique has been applied to fuel slug fabrication for the Experimental Breeder Reactor-II (EBR-II) driver and the Fast Flux Test Facility (FFTF) fuel pins. Because of the simplistic nature of the process and equipment, compared to other processes examined, this process has been successfully used in a remote operation environment for fueling of the EBR-II reactor. In this study, vacuum injection casting suitable for remote operation has been developed to fabricate metallic fuel for an SFR. Vacuum injection casting technique was developed to fabricate metallic fuel for an SFR. The appearance of the fabricated U-10wt.%Zr fuel was generally sound and the internal integrity was found to be satisfactory through gamma-ray radiography. Minimum fuel losses after casting relative to the initial charge amount of U-10wt.%Zr fuel slugs met the proposed goal of less than 0.1% fuel losses during fabrication. Modifications of the current facility system and advanced casting techniques are underway to produce higher quality fuel slugs.

  14. Drift flux model as approximation of two fluid model for two phase dispersed and slug flow in tube

    Energy Technology Data Exchange (ETDEWEB)

    Nigmatulin, R.I.

    1995-09-01

    The analysis of one-dimensional schematizing for non-steady two-phase dispersed and slug flow in tube is presented. Quasi-static approximation, when inertia forces because of the accelerations of the phases may be neglected, is considered. Gas-liquid bubbly and slug vertical upward flows are analyzed. Non-trivial theoretical equations for slip velocity for these flows are derived. Juxtaposition of the derived equations for slip velocity with the famous Zuber-Findlay correlation as cross correlation coefficients is criticized. The generalization of non-steady drift flux Wallis theory taking into account influence of wall friction on the bubbly or slug flows for kinematical waves is considered.

  15. Drift flux model as approximation of two fluid model for two phase dispersed and slug flow in tube

    International Nuclear Information System (INIS)

    Nigmatulin, R.I.

    1995-01-01

    The analysis of one-dimensional schematizing for non-steady two-phase dispersed and slug flow in tube is presented. Quasi-static approximation, when inertia forces because of the accelerations of the phases may be neglected, is considered. Gas-liquid bubbly and slug vertical upward flows are analyzed. Non-trivial theoretical equations for slip velocity for these flows are derived. Juxtaposition of the derived equations for slip velocity with the famous Zuber-Findlay correlation as cross correlation coefficients is criticized. The generalization of non-steady drift flux Wallis theory taking into account influence of wall friction on the bubbly or slug flows for kinematical waves is considered

  16. Applicability of the black slug Arion ater for monitoring exposure to polycyclic aromatic hydrocarbons and their subsequent bioactivation into DNA binding metabolites

    NARCIS (Netherlands)

    Hamers, T.; Kalis, E.J.J.; Berg, van den J.H.J.; Maas, L.M.; Schooten, van F.J.; Murk, A.J.

    2004-01-01

    The applicability of terrestrial black slugs Arion ater (Mollusca, Gastropoda) was studied for biomonitoring environmental exposure to polycyclic aromatic hydrocarbons (PAHs). In laboratory experiments, slugs were orally exposed to benzo[a]pyrene (BaP) for a short term (3 days) or a long term (119

  17. Removal of Molluscicidal Bait Pellets by Earthworms and its Impact on Control of the Gray Field Slug, Derocerus reticulatum Mueller, in Western Oregon Grass Seed Fields

    Science.gov (United States)

    Slugs are common pests of grass seed fields in western Oregon and are currently controlled using bait pellets that often fail to give adequate protection. Here we demonstrate the loss of bait pellet products to earthworms and its adverse effects on controlling slugs. Three years of field and greenho...

  18. An investigation on near wall transport characteristics in an adiabatic upward gas-liquid two-phase slug flow

    Science.gov (United States)

    Zheng, Donghong; Che, Defu

    2007-08-01

    The near-wall transport characteristics, inclusive of mass transfer coefficient and wall shear stress, which have a great effect on gas-liquid two-phase flow induced internal corrosion of low alloy pipelines in vertical upward oil and gas mixing transport, have been both mechanistically and experimentally investigated in this paper. Based on the analyses on the hydrodynamic characteristics of an upward slug unit, the mass transfer in the near wall can be divided into four zones, Taylor bubble nose zone, falling liquid film zone, Taylor bubble wake zone and the remaining liquid slug zone; the wall shear stress can be divided into two zones, the positive wall shear stress zone associated with the falling liquid film and the negative wall shear stress zone associated with the liquid slug. Based on the conventional mass transfer and wall shear stress characteristics formulas of single phase liquid full-pipe turbulent flow, corrected normalized mass transfer coefficient formula and wall shear stress formula are proposed. The calculated results are in good agreement with the experimental data. The shear stress and the mass transfer coefficient in the near wall zone are increased with the increase of superficial gas velocity and decreased with the increase of superficial liquid velocity. The mass transfer coefficients in the falling liquid film zone and the wake zone of leading Taylor bubble are lager than those in the Taylor bubble nose zone and the remaining liquid slug zone, and the wall shear stress associated falling liquid film is larger than that associated the liquid slug. The mass transfer coefficient is within 10-3 m/s, and the wall shear stress below 103 Pa. It can be concluded that the alternate wall shear stress due to upward gas-liquid slug flow is considered to be the major cause of the corrosion production film fatigue cracking.

  19. Development of converter to change gas-liquid two-phase slug flow to bubbly flow in a vertical tube

    International Nuclear Information System (INIS)

    Sakaguchi, T.; Minagawa, H.; Hamaguchi, H.; Shakutusi, H.; Ono, M.; Mizuta, H.

    1989-01-01

    The mechanical and/or the thermal fatigue fracture of pipelines due to the pulsating characteristics of slug flow will be prevented if slug flow is changed to bubbly flow. Then kinds of flow pattern converters were developed and tested in a vertical tube of 30.3 mm I.D. This paper reports that the converter composed of five stages of porous plates is useful. The sintered porous plates of spherical particles made acrylonitrile-butadiene-styrene resin and bronze are selected from 76 kinds of porous plates

  20. Target innervation is necessary for neuronal polyploidization in the terrestrial slug Limax.

    Science.gov (United States)

    Matsuo, Ryota; Yamagishi, Miki; Wakiya, Kyoko; Tanaka, Yoko; Ito, Etsuro

    2013-08-01

    The brain of gastropod mollusks contains many giant neurons with polyploid genomic DNAs. Such DNAs are generated through repeated DNA endoreplication during body growth. However, it is not known what triggers DNA endoreplication in neurons. There are two possibilities: (1) DNAs are replicated in response to some unknown molecules in the hemolymph that reflect the nutritive status of the animal; or (2) DNAs are replicated in response to some unknown factors that are retrogradely transported through axons from the innervated target organs. We first tested whether hemolymph with rich nutrition could induce DNA endoreplication. We tested whether the transplanted brain exhibits enhanced DNA endoreplication like an endogenous brain does when transplanted into the homocoel of the body of a slug whose body growth is promoted by an increased food supply. However, no enhancement was observed in the frequency of DNA endoreplication when we compared the transplanted brains in the growth-promoted and growth-suppressed host slugs, suggesting that the humoral environment is irrelevant to triggering the body growth-dependent DNA endoreplication. Next, we tested the requirement of target innervation by surgically dissecting a unilateral posterior pedal nerve of an endogenous brain. Substantially lower number of neurons exhibited DNA endoreplication in the pedal ganglion ipsilateral to the dissected nerve. These results support the view that enhanced DNA endoreplication is mediated by target innervation and is not brought about through the direct effect of humoral factors in the hemolymph during body growth. Copyright © 2013 Wiley Periodicals, Inc.

  1. A method for the estimation of dual transmissivities from slug tests

    Science.gov (United States)

    Wolny, Filip; Marciniak, Marek; Kaczmarek, Mariusz

    2018-03-01

    Aquifer homogeneity is usually assumed when interpreting the results of pumping and slug tests, although aquifers are essentially heterogeneous. The aim of this study is to present a method of determining the transmissivities of dual-permeability water-bearing formations based on slug tests such as the pressure-induced permeability test. A bi-exponential rate-of-rise curve is typically observed during many of these tests conducted in heterogeneous formations. The work involved analyzing curves deviating from the exponential rise recorded at the Belchatow Lignite Mine in central Poland, where a significant number of permeability tests have been conducted. In most cases, bi-exponential movement was observed in piezometers with a screen installed in layered sediments, each with a different hydraulic conductivity, or in fissured rock. The possibility to identify the flow properties of these geological formations was analyzed. For each piezometer installed in such formations, a set of two transmissivity values was calculated piecewise based on the interpretation algorithm of the pressure-induced permeability test—one value for the first (steeper) part of the obtained rate-of-rise curve, and a second value for the latter part of the curve. The results of transmissivity estimation for each piezometer are shown. The discussion presents the limitations of the interpretational method and suggests future modeling plans.

  2. CFD Analysis of a Slug Mixing Experiment Conducted on a VVER-1000 Model

    Directory of Open Access Journals (Sweden)

    F. Moretti

    2009-01-01

    Full Text Available A commercial CFD code was applied, for validation purposes, to the simulation of a slug mixing experiment carried out at OKB “Gidropress” scaled facility in the framework of EC TACIS project R2.02/02: “Development of safety analysis capabilities for VVER-1000 transients involving spatial variations of coolant properties (temperature or boron concentration at core inlet.” Such experimental model reproduces a VVER-1000 nuclear reactor and is aimed at investigating the in-vessel mixing phenomena. The addressed experiment involves the start-up of one of the four reactor coolant pumps (the other three remaining idle, and the presence of a tracer slug on the starting loop, which is thus transported to the reactor pressure vessel where it mixes with the clear water. Such conditions may occur in a boron dilution scenario, hence the relevance of the addressed phenomena for nuclear reactor safety. Both a pretest and a posttest CFD simulations of the mentioned experiment were performed, which differ in the definition of the boundary conditions (based either on nominal quantities or on measured quantities, resp.. The numerical results are qualitatively and quantitatively analyzed and compared against the measured data in terms of space and time tracer distribution at the core inlet. The improvement of the results due to the optimization of the boundary conditions is evidenced, and a quantification of the simulation accuracy is proposed.

  3. Transition from annular flow to plug/slug flow in condensation of steam in microchannels

    Energy Technology Data Exchange (ETDEWEB)

    Quan, Xiaojun; Cheng, Ping; Wu, Huiying [School of Mechanical and Power Engineering, Shanghai Jiaotong University, 800 Dong Chuan Road, Shanghai 200240 (China)

    2008-02-15

    A visualization study has been conducted to investigate the transition from annular flow to plug/slug flow in the condensation of steam in two different sets of parallel microchannels, having hydraulic diameters of 90 {mu}m and 136 {mu}m, respectively. The steam in the parallel microchannels was cooled on the bottom by forced convection of water and by natural convection of air from the top. It is found that the location, where the transition from annular flow to plug/slug flow takes place, depends on mass flux and cooling rate of steam. The effects of mass flux and cooling rate on the occurrence frequency of the injection flow in a single microchannel, having a hydraulic diameter of 120 {mu}m and 128 {mu}m, respectively, are investigated. It is found that two different shapes of injection flow occur in the smooth annular flow in microchannels: injection flow with unsteady vapor ligament occurring at low mass flux (or high cooling rate) and injection flow with steady vapor ligament occurring at high mass flux (or low cooling rate). It is also found that increase of steam mass flux, decrease of cooling rate, or decrease of the microchannel diameter tends to enhance instability of the condensate film on the wall, resulting in occurrence of the injection flow further toward the outlet with an increase in occurrence frequency. (author)

  4. Chondrogenic potential of human mesenchymal stem cells and expression of Slug transcription factor.

    Science.gov (United States)

    Brini, Anna T; Niada, Stefania; Lambertini, Elisabetta; Torreggiani, Elena; Arrigoni, Elena; Lisignoli, Gina; Piva, Roberta

    2015-06-01

    The scientific literature rarely reports experimental failures or inconsistent outcomes in the induction of cell differentiation; however, researchers commonly experience poor or unsuccessful responses to differentiating agents when culturing stem cells. One way of investigating the underlying reasons for such responses is to look at the basal expression levels of specific genes in multipotent stem cells before the induction of differentiation. In addition to shedding light on the complex properties of stem cells and the molecular modulation of differentiation pathways, this strategy can also lead to the development of important time- and money-saving tools that aid the efficient selection of cellular specimens--in this case, stem cells that are more prone to differentiate towards specific lineages and are therefore more suitable for cell-based therapeutic protocols in regenerative medicine. To address this latter aspect, this study focused on understanding the reasons why some human mesenchymal stem cell (hMSC) samples are less efficient at differentiating towards chondrogenesis. This study shows that analysis of the basal expression levels of Slug, a negative regulator of chondrogenesis in hMSC, provides a rapid and simple tool for distinguishing stem cell samples with the potential to form a cartilage-like matrix, and that are therefore suitable for cartilage tissue engineering. It is shown that high basal levels of Slug prevent the chondrogenic differentiation of hMSCs, even in the presence of transforming growth factor-β and elevated levels of Sox9. Copyright © 2013 John Wiley & Sons, Ltd.

  5. A Review of the Multilevel Slug Test for Characterizing Aquifer Heterogeneity

    Directory of Open Access Journals (Sweden)

    Chia-Shyun Chen

    2012-01-01

    Full Text Available All aquifers are heterogeneous to a certain degree. The spatial distribution of hydraulic conductivity K(x, y, z, or aquifer heterogeneity, significantly influences the groundwater flow movement and associated solute transport. Of particular importance in designing an in-situ remediation plan is a knowledge of low-K layers because they are less accessible to remedial agents and form a bottleneck in remediation. The characterization of aquifer heterogeneity is essential to the solution of many practical and scientific groundwater problems. This article reviews the field technique using the multilevel slug test (MLST, which determines a series of K estimates at depths of interest in a well by making use of a double-packer system. The K(z obtained manifests the vertical variation of hydraulic conductivity in the vicinity of the test well, and the combination of K(z from different wells gives rise to a three-dimensional description of K(x, y, z. The MLST response is rather sensitive to hydraulic conductivity variation; e.g., it is oscillatory for highly permeable conditions (K > 5 × 10-4 m s-1 and a nonoscillatory for K < 5 × 10-4 m s-1. In this article we discuss the instrumentation of the double-packer system, the implementation of the depth-specific slug test, the data analysis methods for a spectrum of response characteristics usually observed in the field, and field applications of the MLST.

  6. Experimental investigations and modelling on the transition from bubble to slug flow in vertical pipes

    International Nuclear Information System (INIS)

    Lucas, D.; Krepper, E.; Prasser, H.M.

    2003-01-01

    To qualify CFD codes for two-phase flows, they have to be equipped with constitutive laws describing the interaction between the gaseous and the liquid phases. In the case of bubble flow this particularly concerns the forces acting on the bubbles and bubble coalescence and break-up. To obtain detailed experimental data, an electrode wire-mesh sensor was used, which enables the measurement of the phase distribution with a very high resolution in space and in time. Air-water flow at ambient conditions in a vertical pipe (51.2 mm inner diameter) is investigated to have well defined boundary conditions. Local bubble size distributions are calculated from the data. The measurements were done in different distances from the gas injection device. As a result the development of bubble size distributions as well as the development of the radial gas fraction profiles can be studied. It was found, that the bubble size distribution as well as local effects determine the transition from bubble flow to slug flow. The data are used for the development of a model, which predicts the development of the bubble size distribution and the transition from bubble flow to slug flow in case of stationary flow in a vertical pipe. (orig.)

  7. Wire-mesh and ultrasound techniques applied for the characterization of gas-liquid slug flow

    Energy Technology Data Exchange (ETDEWEB)

    Ofuchi, Cesar Y.; Sieczkowski, Wytila Chagas; Neves Junior, Flavio; Arruda, Lucia V.R.; Morales, Rigoberto E.M.; Amaral, Carlos E.F.; Silva, Marco J. da [Federal University of Technology of Parana, Curitiba, PR (Brazil)], e-mails: ofuchi@utfpr.edu.br, wytila@utfpr.edu.br, neves@utfpr.edu.br, lvrarruda@utfpr.edu.br, rmorales@utfpr.edu.br, camaral@utfpr.edu.br, mdasilva@utfpr.edu.br

    2010-07-01

    Gas-liquid two-phase flows are found in a broad range of industrial applications, such as chemical, petrochemical and nuclear industries and quite often determine the efficiency and safety of process and plants. Several experimental techniques have been proposed and applied to measure and quantify two-phase flows so far. In this experimental study the wire-mesh sensor and an ultrasound technique are used and comparatively evaluated to study two-phase slug flows in horizontal pipes. The wire-mesh is an imaging technique and thus appropriated for scientific studies while ultrasound-based technique is robust and non-intrusive and hence well suited for industrial applications. Based on the measured raw data it is possible to extract some specific slug flow parameters of interest such as mean void fraction and characteristic frequency. The experiments were performed in the Thermal Sciences Laboratory (LACIT) at UTFPR, Brazil, in which an experimental two-phase flow loop is available. The experimental flow loop comprises a horizontal acrylic pipe of 26 mm diameter and 9 m length. Water and air were used to produce the two phase flow under controlled conditions. The results show good agreement between the techniques. (author)

  8. Online recognition of the multiphase flow regime and study of slug flow in pipeline

    International Nuclear Information System (INIS)

    Guo Liejin; Bai Bofeng; Zhao Liang; Wang Xin; Gu Hanyang

    2009-01-01

    sensor performance. Among various flow patterns of gas-liquid flow, slug flow occurs frequently in the petroleum, chemical, civil and nuclear industries. In the offshore oil and gas field, the maximum slug length and its statistical distribution are very important for the design of separator and downstream processing facility at steady state operations. However transient conditions may be encountered in the production, such as operational upsets, start-up, shut-down, pigging and blowdown, which are key operational and safety issues related to oil field development. So it is necessary to have an understanding the flow parameters under transient conditions. In this paper, the evolution of slug length along a horizontal pipe in gas-liquid flow is also studied in details and then an experimental study of flowrate transients in slug flow is provided. Also, the special gas-liquid flow phenomena easily encountered in the life span of offshore oil fields, called severe slugging, is studied experimentally and some results are presented.

  9. Banana Slug

    Science.gov (United States)

    First, Lucas

    2009-01-01

    Everyone insists that a person should go to a college that is right for him/her, somewhere that fits who he/she is, a place where a they belong. There are more than 4,000 colleges and universities in this country; how will a person find the one that is right for them? In this article, the author suggests that one should follow the mascot when…

  10. The gastropod menace: slugs on Brassica plants affect caterpillar survival through consumption and interference with parasitoid attraction

    Science.gov (United States)

    Terrestrial molluscs and insect herbivores play a major role as plant consumers in a number of ecosystems, but their direct and indirect interactions have hardly been explored. The omnivorous nature of slugs makes them potential disrupters of predator-prey relationships, as a direct threat to small ...

  11. Hydrodynamics of gas-liquid slug flow along vertical pipes in turbulent regime-An experimental study

    Energy Technology Data Exchange (ETDEWEB)

    Mayor, T.S.; Ferreira, V.; Pinto, A.M.F.R. [Centro de Estudos de Fenomenos de Transporte, Departamento de Engenharia Quimica, Faculdade de Engenharia da Universidade do Porto, Rua Dr. Roberto Frias 4200-465 Porto (Portugal); Campos, J.B.L.M. [Centro de Estudos de Fenomenos de Transporte, Departamento de Engenharia Quimica, Faculdade de Engenharia da Universidade do Porto, Rua Dr. Roberto Frias 4200-465 Porto (Portugal)], E-mail: jmc@fe.up.pt

    2008-08-15

    An experimental study on free-bubbling gas-liquid (air-water) vertical slug flow was developed using a non-intrusive image analysis technique. The flow pattern in the near-wake of the bubbles and in the main liquid between bubbles was turbulent. A single correlation for the bubble-to-bubble interaction is proposed, relating the trailing bubble velocity to the length of the liquid slug ahead of the bubble. The proposed correlation is shown to be independent of column diameter, column vertical coordinate, superficial liquid and gas velocities and the velocity and length of the leading bubble. Frequency distribution curves, averages, modes and standard deviations are reported, for distributions of bubble velocity, bubble length and liquid slug length, for each experimental condition studied. Good agreement was found between theoretical predictions and experimental results regarding the upward velocity of undisturbed bubbles, in a 0.032 m internal diameter column. A considerable discrepancy was found, though, for a 0.052 m internal diameter column. The acquired experimental data are crucial for the development and validation of a robust slug flow simulator.

  12. Hydrodynamics of gas-liquid slug flow along vertical pipes in turbulent regime-An experimental study

    International Nuclear Information System (INIS)

    Mayor, T.S.; Ferreira, V.; Pinto, A.M.F.R.; Campos, J.B.L.M.

    2008-01-01

    An experimental study on free-bubbling gas-liquid (air-water) vertical slug flow was developed using a non-intrusive image analysis technique. The flow pattern in the near-wake of the bubbles and in the main liquid between bubbles was turbulent. A single correlation for the bubble-to-bubble interaction is proposed, relating the trailing bubble velocity to the length of the liquid slug ahead of the bubble. The proposed correlation is shown to be independent of column diameter, column vertical coordinate, superficial liquid and gas velocities and the velocity and length of the leading bubble. Frequency distribution curves, averages, modes and standard deviations are reported, for distributions of bubble velocity, bubble length and liquid slug length, for each experimental condition studied. Good agreement was found between theoretical predictions and experimental results regarding the upward velocity of undisturbed bubbles, in a 0.032 m internal diameter column. A considerable discrepancy was found, though, for a 0.052 m internal diameter column. The acquired experimental data are crucial for the development and validation of a robust slug flow simulator

  13. Learning control for riser-slug elimination and production-rate optimization for an offshore oil and gas production process

    DEFF Research Database (Denmark)

    Pedersen, Simon; Løhndorf, Petar Durdevic; Yang, Zhenyu

    2014-01-01

    , (ii) maximizing the production rate at the riser of an offshore production platform, by manipulating a topside choke valve through a learning switching model-free PID controller. The results show good steady-state performance, though a long settling time due to the unknown reference for no slugging...

  14. Field experiments using the rhabditid nematode Phasmarhabditis hermaphrodita or salt as control measures against slugs in green asparagus

    NARCIS (Netherlands)

    Ester, A.; Rozen, van K.; Molendijk, L.P.G.

    2003-01-01

    Green asparagus (Asparagus officinalis L.) crops are frequently damaged by the grey field slug (Deroceras reticulatum). Most damage occurs in the soil, although some asparagus spears are attacked above ground. In the Netherlands damage occurs especially during the first 5 weeks of harvesting, from

  15. Cutaneous application of an accessory-gland secretion after sperm exchange in a terrestrial slug (Mollusca : Pulmonata)

    NARCIS (Netherlands)

    Benke, Mandy; Reise, Heike; Montagne-Wajer, Kora; Koene, Joris M

    Competition for fertilisation in hermaphroditic animals seems to have led to many odd behaviours and complex morphologies involved in the transfer of accessory-gland products to the partner. Terrestrial slugs of the genus Deroceras show remarkably elaborate and interspecifically diverse penis

  16. Carotenoids of Sea Angels Clione limacina and Paedoclione doliiformis from the Perspective of the Food Chain

    Directory of Open Access Journals (Sweden)

    Takashi Maoka

    2014-03-01

    Full Text Available Sea angels, Clione limacina and Paedoclione doliiformis, are small, floating sea slugs belonging to Gastropoda, and their gonads are a bright orange-red color. Sea angels feed exclusively on a small herbivorous sea snail, Limacina helicina. Carotenoids in C. limacina, P. doliiformis, and L. helicina were investigated for comparative biochemical points of view. β-Carotene, zeaxanthin, and diatoxanthin were found to be major carotenoids in L. helicina. L. helicina accumulated dietary algal carotenoids without modification. On the other hand, keto-carotenoids, such as pectenolone, 7,8-didehydroastaxanthin, and adonixanthin were identified as major carotenoids in the sea angels C. limacina and P. doliiformis. Sea angels oxidatively metabolize dietary carotenoids and accumulate them in their gonads. Carotenoids in the gonads of sea angels might protect against oxidative stress and enhance reproduction.

  17. Carotenoids of Sea Angels Clione limacina and Paedoclione doliiformis from the Perspective of the Food Chain

    Science.gov (United States)

    Maoka, Takashi; Kuwahara, Takashi; Narita, Masanao

    2014-01-01

    Sea angels, Clione limacina and Paedoclione doliiformis, are small, floating sea slugs belonging to Gastropoda, and their gonads are a bright orange-red color. Sea angels feed exclusively on a small herbivorous sea snail, Limacina helicina. Carotenoids in C. limacina, P. doliiformis, and L. helicina were investigated for comparative biochemical points of view. β-Carotene, zeaxanthin, and diatoxanthin were found to be major carotenoids in L. helicina. L. helicina accumulated dietary algal carotenoids without modification. On the other hand, keto-carotenoids, such as pectenolone, 7,8-didehydroastaxanthin, and adonixanthin were identified as major carotenoids in the sea angels C. limacina and P. doliiformis. Sea angels oxidatively metabolize dietary carotenoids and accumulate them in their gonads. Carotenoids in the gonads of sea angels might protect against oxidative stress and enhance reproduction. PMID:24633249

  18. Expression of Slug in S100β-protein-positive cells of postnatal developing rat anterior pituitary gland.

    Science.gov (United States)

    Horiguchi, Kotaro; Fujiwara, Ken; Tsukada, Takehiro; Yako, Hideji; Tateno, Kozue; Hasegawa, Rumi; Takigami, Shu; Ohsako, Shunji; Yashiro, Takashi; Kato, Takako; Kato, Yukio

    2016-02-01

    Among heterogeneous S100β-protein-positive (S100β-positive) cells, star-like cells with extended cytoplasmic processes, the so-called folliculo-stellate cells, envelop hormone-producing cells or interconnect homophilically in the anterior pituitary. S100β-positive cells are known, from immunohistochemistry, to emerge from postnatal day (P) 10 and to proliferate and migrate in the parenchyma of the anterior pituitary with growth. Recent establishment of S100β-GFP transgenic rats expressing specifically green fluorescent protein (GFP) under the control of the S100β-promoter has allowed us to observe living S100β-positive cells. In the present study, we first confirmed that living S100β-positive cells in tissue cultures of S100β-GFP rat pituitary at P5 were present prior to P10 by means of confocal laser microscopy and that they proliferated and extended their cytoplasmic processes. Second, we examined the expression of the Snail-family zinc-finger transcription factors, Snail and Slug, to investigate the mechanism behind the morphological changes and the proliferation of S100β-positive cells. Interestingly, we detected Slug expression in S100β-positive cells and its increase together with development in the anterior pituitary. To analyze downstream of SLUG in S100β-positive cells, we utilized specific small interfering RNA for Slug mRNAs and observed that the expression of matrix metalloprotease (Mmp) 9, Mmp14 and chemokine Cxcl12 was down-regulated and that morphological changes and proliferation were decreased. Thus, our findings suggest that S100β-positive cells express Slug and that its expression is important for subsequent migration and proliferation.

  19. Expression analysis of E-cadherin, Slug and GSK3β in invasive ductal carcinoma of breast

    International Nuclear Information System (INIS)

    Prasad, Chandra P; Rath, Gayatri; Mathur, Sandeep; Bhatnagar, Dinesh; Parshad, Rajinder; Ralhan, Ranju

    2009-01-01

    Cancer progression is linked to a partially dedifferentiated epithelial cell phenotype. The signaling pathways Wnt, Hedgehog, TGF-β and Notch have been implicated in experimental and developmental epithelial mesenchymal transition (EMT). Recent findings from our laboratory confirm that active Wnt/β-catenin signaling is critically involved in invasive ductal carcinomas (IDCs) of breast. In the current study, we analyzed the expression patterns and relationships between the key Wnt/β-catenin signaling components- E-cadherin, Slug and GSK3β in IDCs of breast. Of the 98 IDCs analyzed, 53 (54%) showed loss/or reduced membranous staining of E-cadherin in tumor cells. Nuclear accumulation of Slug was observed in 33 (34%) IDCs examined. Loss or reduced level of cytoplasmic GSK3β expression was observed in 52/98 (53%) cases; while 34/98 (35%) tumors showed nuclear accumulation of GSK3β. Statistical analysis revealed associations of nuclear Slug expression with loss of membranous E-cadherin (p = 0.001); nuclear β-catenin (p = 0.001), and cytoplasmic β-catenin (p = 0.005), suggesting Slug mediated E-cadherin suppression via the activation of Wnt/β-catenin signaling pathway in IDCs. Our study also demonstrated significant correlation between GSK3β nuclear localization and tumor grade (p = 0.02), suggesting its association with tumor progression. The present study for the first time provided the clinical evidence in support of Wnt/β-catenin signaling upregulation in IDCs and key components of this pathway - E-cadherin, Slug and GSK3β with β-catenin in implementing EMT in these cells

  20. Expression analysis of E-cadherin, Slug and GSK3β in invasive ductal carcinoma of breast

    Energy Technology Data Exchange (ETDEWEB)

    Prasad, Chandra P [Department of Anatomy, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi (India); Department of Biochemistry, All India Institute of Medical Sciences, New Delhi (India); Rath, Gayatri [Department of Anatomy, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi (India); Mathur, Sandeep [Department of Pathology, All India Institute of Medical Sciences, New Delhi (India); Bhatnagar, Dinesh [Department of Surgery, Vardhman Mahavir Medical College and Safdarjung Hospital, New Dehi (India); Parshad, Rajinder [Department of Surgery, All India Institute of Medical Sciences, New Delhi -110029 (India); Ralhan, Ranju [Department of Biochemistry, All India Institute of Medical Sciences, New Delhi (India); Sonshine Family Centre for Head & Neck Disease, Mount Sinai Hospital, 600 University Avenue, Room 6-500, Toronto, Ontario M5G 1X5 (Canada); Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Hospital, 600 University Avenue, Room 6-500, Toronto, Ontario M5G 1X5 (Canada); Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, 600 University Avenue, Room 6-500, Toronto, Ontario M5G 1X5 (Canada); Department of Otolaryngology-Head and Neck Surgery, University of Toronto, Toronto, M5G 2N2 (Canada)

    2009-09-14

    Cancer progression is linked to a partially dedifferentiated epithelial cell phenotype. The signaling pathways Wnt, Hedgehog, TGF-β and Notch have been implicated in experimental and developmental epithelial mesenchymal transition (EMT). Recent findings from our laboratory confirm that active Wnt/β-catenin signaling is critically involved in invasive ductal carcinomas (IDCs) of breast. In the current study, we analyzed the expression patterns and relationships between the key Wnt/β-catenin signaling components- E-cadherin, Slug and GSK3β in IDCs of breast. Of the 98 IDCs analyzed, 53 (54%) showed loss/or reduced membranous staining of E-cadherin in tumor cells. Nuclear accumulation of Slug was observed in 33 (34%) IDCs examined. Loss or reduced level of cytoplasmic GSK3β expression was observed in 52/98 (53%) cases; while 34/98 (35%) tumors showed nuclear accumulation of GSK3β. Statistical analysis revealed associations of nuclear Slug expression with loss of membranous E-cadherin (p = 0.001); nuclear β-catenin (p = 0.001), and cytoplasmic β-catenin (p = 0.005), suggesting Slug mediated E-cadherin suppression via the activation of Wnt/β-catenin signaling pathway in IDCs. Our study also demonstrated significant correlation between GSK3β nuclear localization and tumor grade (p = 0.02), suggesting its association with tumor progression. The present study for the first time provided the clinical evidence in support of Wnt/β-catenin signaling upregulation in IDCs and key components of this pathway - E-cadherin, Slug and GSK3β with β-catenin in implementing EMT in these cells.

  1. Simultaneous PIV and pulsed shadow technique in slug flow: a solution for optical problems

    Energy Technology Data Exchange (ETDEWEB)

    Nogueira, S. [Karman Institute for Fluid Dynamics, Chaussee de Waterloo 72, B-1640, Rhode Saint Genese (Belgium); Centro de Estudos de Fenomenos de Transporte, Departamento de Eng. Quimica, Faculdade de Engenharia da Universidade do Porto, Rua Dr. Roberto Frias, 4200-465, Porto (Portugal); Sousa, R.G.; Pinto, A.M.F.R.; Campos, J.B.L.M. [Centro de Estudos de Fenomenos de Transporte, Departamento de Eng. Quimica, Faculdade de Engenharia da Universidade do Porto, Rua Dr. Roberto Frias, 4200-465, Porto (Portugal); Riethmuller, M.L. [Karman Institute for Fluid Dynamics, Chaussee de Waterloo 72, B-1640, Rhode Saint Genese (Belgium)

    2003-12-01

    A recent technique of simultaneous particle image velocimetry (PIV) and pulsed shadow technique (PST) measurements, using only one black and white CCD camera, is successfully applied to the study of slug flow. The experimental facility and the operating principle are described. The technique is applied to study the liquid flow pattern around individual Taylor bubbles rising in an aqueous solution of glycerol with a dynamic viscosity of 113 x 10{sup -3} Pa s. With this technique the optical perturbations found in PIV measurements at the bubble interface are completely solved in the nose and in annular liquid film regions as well as in the rear of the bubble for cases in which the bottom is flat. However, for Taylor bubbles with concave oblate bottoms, some optical distortions appear and are discussed. The measurements achieved a spatial resolution of 0.0022 tube diameters. The results reported show high precision and are in agreement with theoretical and experimental published data. (orig.)

  2. Transition from slug to annular flow in horizontal air-water flow

    International Nuclear Information System (INIS)

    Reismann, J.; John, H.; Seeger, W.

    1981-11-01

    The transition from slug to annular flow in horizontal air-water and steam-water flow was investigated. Test sections of 50; 66.6 and 80 mm ID were used. The system pressure was 0.2 and 0.5 MPa in the air-water experiments and 2.5; 5; 7.5 and 10 MPa in the steam-water experiments. For flow pattern detection local impedance probes were used. This method was compared in a part of the experiments with differential pressure and gamma-beam measurements. The flow regime boundary is shifting strongly to smaller values of the superficial gas velocity with increasing pressure. Correlations from literature fit unsatisfactorily the experimental results. A new correlation is presented. (orig.) [de

  3. Spatial variability of hydraulic conductivity of an unconfined sandy aquifer determined by a mini slug test

    DEFF Research Database (Denmark)

    Bjerg, Poul Løgstrup; Hinsby, Klaus; Christensen, Thomas Højlund

    1992-01-01

    The spatial variability of the hydraulic conductivity in a sandy aquifer has been determined by a mini slug test method. The hydraulic conductivity (K) of the aquifer has a geometric mean of 5.05 × 10−4 m s−1, and an overall variance of 1n K equal to 0.37 which corresponds quite well to the results...... obtained by two large scale tracer experiments performed in the aquifer. A geological model of the aquifer based on 31 sediment cores, proposed three hydrogeological layers in the aquifer concurrent with the vertical variations observed with respect to hydraulic conductivity. The horizontal correlation......, to be in the range of 0.3–0.5 m compared with a value of 0.42 m obtained in one of the tracer tests performed....

  4. Standard Test Method for Measuring Heat-Transfer Rate Using a Thermal Capacitance (Slug) Calorimeter

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2008-01-01

    1.1 This test method describes the measurement of heat transfer rate using a thermal capacitance-type calorimeter which assumes one-dimensional heat conduction into a cylindrical piece of material (slug) with known physical properties. 1.2 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use. 1.3 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard. Note 1—For information see Test Methods E 285, E 422, E 458, E 459, and E 511.

  5. A user interface for the Kansas Geological Survey slug test model.

    Science.gov (United States)

    Esling, Steven P; Keller, John E

    2009-01-01

    The Kansas Geological Survey (KGS) developed a semianalytical solution for slug tests that incorporates the effects of partial penetration, anisotropy, and the presence of variable conductivity well skins. The solution can simulate either confined or unconfined conditions. The original model, written in FORTRAN, has a text-based interface with rigid input requirements and limited output options. We re-created the main routine for the KGS model as a Visual Basic macro that runs in most versions of Microsoft Excel and built a simple-to-use Excel spreadsheet interface that automatically displays the graphical results of the test. A comparison of the output from the original FORTRAN code to that of the new Excel spreadsheet version for three cases produced identical results.

  6. Automatic detection of ''bore slug'' in tubes; Detection automatique des manques de metal internes sur tubes

    Energy Technology Data Exchange (ETDEWEB)

    Bisiaux, B.; Deutsch, S.; Tailleux, O.; Mette, F. [CEV Vallourec, Aulnoye (France)

    2001-07-01

    During the tube manufacturing for the petroleum industry, the lacks of internal metal (called Bore Slug) can be created during the hot rolling. These large defects are not good detected by the classic UT and by the wall thickness measurement. That's why VALLOUREC developed an automatic UT device which works by transmission. Nevertheless, this system is too little selective and can cause no doubtful pipes (tubes good detected bad). We adapted a Bore Slug control system on the VMOG UK RP20 at the end of August. The results are rather good and showed a good detection of the Bore Slug and very little no doubtful pipes. (authors)

  7. Slug-tests in PP- and PVP-holes at Olkiluoto in 2006

    International Nuclear Information System (INIS)

    Keskitalo, K.; Lindgren, S.

    2007-11-01

    As part of the program for the final disposal of the nuclear fuel waste, Posiva Oy investigates the hydrological conditions at the Olkiluoto island. The hydraulic conductivity in the shallow holes OL-PP5, OL-PP9, OL-PP36, OL-PP39, OL-PVP4A, OL-PVP4B, OL-PVP6A, OL-PVP6B and OL-PVP14 was measured in summer 2006. The length of PP-holes varies between 12 and 15 m, and the test sections (1 m) are located in the bedrock. PVP-tubes have a length up to 10 m, and the test sections (2 m) are located in the overburden. The measurements were done using the slug-test technique. In the slug-test, the hydraulic head in the borehole is abruptly changed either by pouring water into the borehole or by lowering the pressure sensor. The conductivity is interpreted based on the recovery of the water level. This report presents the field measurements and their interpretation. The interpretation has been done using the Hvorslev's method, and for reference, conductivity has also been calculated according to Thiem's equation. According to the results, hydraulic conductivity in PP-holes ranges from 10 -9 m/s to 10 -6 m/s and in PVP-tubes from 10 -8 m/s to 10 -5 m/s. The range is similar as observed in measurements of years 2002, 2004 and 2005. In general the results are consistent with the results obtained in earlier measurements. Some exceptions exist in OL-PP9, where the conductivity is lower than in the 2005 measurements, but still at the same level as in the 2002 measurements. Also, the results agree with hydraulic conductivity interpreted from the pre-pumping done in connection with the groundwater sampling. (orig.)

  8. Regulation of Membrane-Type 4 Matrix Metalloproteinase by SLUG Contributes to Hypoxia-Mediated Metastasis

    Directory of Open Access Journals (Sweden)

    Chi-Hung Huang

    2009-12-01

    Full Text Available The hypoxic tumor environment has been shown to be critical to cancer metastasis through the promotion of angiogenesis, induction of epithelial-mesenchymal transition (EMT, and acquisition of invasive potential. However, the impact of hypoxia on the expression profile of the proteolytic enzymes involved in invasiveness is relatively unknown. Membrane-type 4 matrix metalloproteinase (MT4-MMP is a glycosyl-phosphatidyl inositol-anchored protease that has been shown to be overexpressed in human cancers. However, detailed mechanisms regarding the regulation and function of MT4-MMP expression in tumor cells remain unknown. Here, we demonstrate that hypoxia or overexpression of hypoxia-inducible factor-1α (HIF-1α induced MT4-MMP expression in human cancer cells. Activation of SLUG, a transcriptional factor regulating the EMT process of human cancers, by HIF-1α was critical for the induction of MT4-MMP under hypoxia. SLUG regulated the transcription of MT4-MMP through direct binding to the E-box located in its proximal promoter. Short-interference RNA-mediated knockdown of MT4-MMP attenuated in vitro invasiveness and in vivo pulmonary colonization of tumor cells without affecting cell migratory ability. MT4-MMP promoted invasiveness and pulmonary colonization through modulation of the expression profile of MMPs and angiogenic factors. Finally, coexpression of HIF-1α and MT4-MMP in human head and neck cancer was predictive of a worse clinical outcome. These findings establish a novel signaling pathway for hypoxia-mediated metastasis and elucidate the underlying regulatory mechanism and functional significance of MT4-MMP in cancer metastasis.

  9. Cellular properties of slug flow in vertical co-current gas-liquid flow: slug-churn transition; Caracteristiques cellulaires du regime a poches en ecoulement gaz-liquide co-courant vertical. Transition vers le regime destructure

    Energy Technology Data Exchange (ETDEWEB)

    Lusseyran, Francois

    1990-12-13

    This research thesis reports the study and description of the structure of a slug flow regime in a co-current vertical cylindrical duct, and the characterization and prediction of its transition towards a slug-churn (de-structured) regime. Flow physical mechanisms highlighted by the measurement of two important dynamics variables (wall friction and thickness of liquid films) are related to hypotheses of cellular models. The author first proposes an overview of slug flow regimes: theoretical steady and one-dimensional analysis, mass assessment equations of cellular models, application to the assessment of the flow rate and of the thickness of the film surrounding the gas slug. In the second part, the author addresses the slug flow regime transition towards the slug-churn regime: assessment of the evolution of flow dynamic properties, use of average wall friction analysis to obtain a relevant transition criterion. The third part presents experimental conditions, and measurement methods: conductometry for thickness measurement, polarography for wall friction measurement, and gas phase detection by using an optic barrier or optic fibres [French] Les ecoulements gaz-liquide en conduite verticale presentent quatre configurations ou regimes d'ecoulement. Ce travail porte sur le regime a poches et sur la transition vers la configuration qui lui succede: le regime destructure (churn flow). Les mesures sont effectuees a 200D du point d'injection du gaz, dans une conduite de 12.2 mm de diametre et pour le couple de fluides eau-azote. Les deux principales grandeurs mesurees en fonction des flux d'entree sont: le frottement parietal instantane (methode electrochimique) et l'epaisseur de film instantanee (methode conductimetrique). Une detection optique simultanee de la presence des phases permet un traitement conditionnel de la base de donnees. Les caracteristiques de la cellule moyenne representative de chaque point de fonctionnement en sont deduites: longueur de la cellule

  10. A comprehensive comparison of four species of Onchidiidae provides insights on the morphological and molecular adaptations of invertebrates from shallow seas to wetlands

    Science.gov (United States)

    Wang, Dongfeng; Li, Jie; Liu, Xin; Wu, Xin

    2018-01-01

    The Onchidiidae family is ideal for studying the evolution of marine invertebrate species from sea to wetland environments. However, comparative studies of Onchidiidae species are rare. A total of 40 samples were collected from four species (10 specimens per onchidiid), and their histological and molecular differences were systematically evaluated to elucidate the morphological foundations underlying the adaptations of these species. A histological analysis was performed to compare the structures of respiratory organs (gill, lung sac, dorsal skin) among onchidiids, and transcriptome sequencing of four representative onchidiids was performed to investigate the molecular mechanisms associated with their respective habitats. Twenty-six SNP markers of Onchidium reevesii revealed some DNA polymorphisms determining visible traits. Non-muscle myosin heavy chain II (NMHC II) and myosin heavy chain (MyHC), which play essential roles in amphibian developmental processes, were found to be differentially expressed in different onchidiids and tissues. The species with higher terrestrial ability and increased integrated expression of Os-MHC (NMHC II gene) and the MyHC gene, illustrating that the expression levels of these genes were associated with the evolutionary degree. This study provides a comprehensive analysis of the adaptions of a diverse and widespread group of invertebrates, the Onchidiidae. Some onchidiids can breathe well through gills and skin when under seawater, and some can breathe well through lung sacs and skin when in wetlands. A histological comparison of respiratory organs and the relative expression levels of two genes provided insights into the adaptions of onchidiids that allowed their transition from shallow seas to wetlands. This work provides a valuable reference and might encourage further study. PMID:29698429

  11. PageRank versatility analysis of multilayer modality-based network for exploring the evolution of oil-water slug flow.

    Science.gov (United States)

    Gao, Zhong-Ke; Dang, Wei-Dong; Li, Shan; Yang, Yu-Xuan; Wang, Hong-Tao; Sheng, Jing-Ran; Wang, Xiao-Fan

    2017-07-14

    Numerous irregular flow structures exist in the complicated multiphase flow and result in lots of disparate spatial dynamical flow behaviors. The vertical oil-water slug flow continually attracts plenty of research interests on account of its significant importance. Based on the spatial transient flow information acquired through our designed double-layer distributed-sector conductance sensor, we construct multilayer modality-based network to encode the intricate spatial flow behavior. Particularly, we calculate the PageRank versatility and multilayer weighted clustering coefficient to quantitatively explore the inferred multilayer modality-based networks. Our analysis allows characterizing the complicated evolution of oil-water slug flow, from the opening formation of oil slugs, to the succedent inter-collision and coalescence among oil slugs, and then to the dispersed oil bubbles. These properties render our developed method particularly powerful for mining the essential flow features from the multilayer sensor measurements.

  12. PLC and SCADA based automation of injection casting process for casting of uranium-zirconium blanket fuel slugs for metallic fuel fabrication

    International Nuclear Information System (INIS)

    Yathish Kumar, G.; Jagadeeschandran, J.; Avvaru, Prafulla Kumar; Yadaw, Abhishek Kumar; Lavakumar, R.; Prabhu, T.V.; Muralidharan, P.; Anthonysamy, S.

    2016-01-01

    Fabrication of metallic (U-6wt.%Zr) slugs involves melting of binary alloy under vacuum and injection casting into quartz moulds at high pressure. Injection casting system housed inside glove box comprises of high vacuum, induction melting, high pressure control, motion control, mould preheating, chamber cooling, crucible handling and glove box pressure control systems. The technology development for process automation of injection casting system and process optimisation for fabrication of metallic (U-6%Zr) slugs is outlined in this paper. (author)

  13. Expression of transcription factors Slug in the lens epithelial cells undergoing epithelial-mesenchymal transition induced by connective tissue growth factor

    Directory of Open Access Journals (Sweden)

    Ying-Na Wang

    2015-10-01

    Full Text Available AIM:To investigate the expression of transcription factors Slug in human lens epithelial cells (HLECs undergoing epithelial-mesenchymal transition (EMT induced by connective tissue growth factor (CTGF.METHODS: HLECs were treated with CTGF of different concentrations (20, 50 and 100 ng/mL or without CTGF (control for 24h. The morphological changes of HLECs were analysed by microscopy. The expression and cellular localization of Slug was evaluated by immumo-fluorescence. Expressions of Slug, E-cadherin and alpha smooth muscle actin (α-SMA were further determined by Western blot analysis. RESULTS: HLECs showed spidle fibrolasts-like characteristics and loosely connected each other after CTGF treatment. The immuno-fluorescence staining indicated that Slug was localized in the nuclei and its expression was induced by CTGF. The relative expressions of Slug protein were 1.64±0.11, 1.96 ±0.03, 3.12 ±0.10, and 4.08±0.14, respectively, in response to control group and treatment with CTGF of 20, 50 and 100 ng/mL (F=443.86, PCONCLUSION: Transcription factor Slug may be involved in EMT of HLECs induced by CTGF in vitro.

  14. Yttria coating on quartz mould inner surface for fabrication of metal fuel slug using injection casting process

    International Nuclear Information System (INIS)

    Vinod, A.V.; Hemanth Kumar, S.; Manivannan, A.; Muralidaran, P.; Anthonysamy, S.; Sudha, R.

    2016-01-01

    Quartz moulds are used for casting metal alloy of U-Zr slugs by injection casting process. Ceramic (Y_2O_3) coating on inner surface of the quartz mould is provided to avoid silica contamination in the fuel slugs during casting. Experiments were carried out to standardise the coating process and optimising various parameters such as particle size of Y_2O_3, choice of suitable binder, method for application of coating, drying and sintering at high temperature to ensure uniformity and strength of coating. Required Coating thickness of ∼40 μm was achieved on a quartz mould of inner diameter of 4.98±0.01mm. Experimental procedure for coating on inner surface of the quartz tubes using yttrium oxide is described in this work. (author)

  15. Profiling of Heterobranchia Sea Slugs from Portuguese Coastal Waters as Producers of Anti-Cancer and Anti-Inflammatory Agents

    Directory of Open Access Journals (Sweden)

    Nelson G. M. Gomes

    2018-04-01

    Full Text Available Bioprospection of marine invertebrates has been predominantly biased by the biological richness of tropical regions, thus neglecting macro-organisms from temperate ecosystems. Species that were not the object of studies on their biochemical composition include the Heterobranchia gastropods Armina maculata, Armina tigrina and Aglaja tricolorata, inhabitants of the Portuguese Atlantic coastal waters. Here, we present for the first time the fatty acid profile of neutral lipids and homarine content of these three species. Qualitative and quantitative differences in the fatty acid content among species points to the existence of a fatty acid profile of neutral lipids, particularly of each genus. The results from cytotoxicity assays, using the acetonic extracts of the gastropods on human gastric adenocarcinoma (AGS and human lung adenocarcinoma (A549 cell lines, revealed a pronounced cytotoxic effect of the A. tigrina extract on both cell lines (IC50 values of 68.75 and 69.77 μg mL−1 for AGS and A549, respectively. It is worth noting the significant reduction of NO levels in LPS-challenged RAW 264.7 macrophages exposed to A. tricolorata extract, at concentrations as low as 125 μg mL−1.

  16. Slug-tests in PP- and PVP-holes at Olkiluoto in 2010

    International Nuclear Information System (INIS)

    Hinkkanen, H.

    2011-07-01

    As part of the program for the final disposal of the nuclear fuel waste, Posiva Oy investigates the hydrological conditions at the Olkiluoto Island. The hydraulic conductivity in the shallow holes OL-PP36, OL-PP39, OL-PVP4A, OL-PVP4B, OL-PVP6A, OL-PVP6B, OL-PVP7A, OL-PVP8A, OL-PVP8B, OL-PVP9A OL-PVP9B, OL-PVP9C, OL-PVP10A, OL-PVP10B, OL-PVP11, OL-PVP12, OLPVP14, OL-PVP17, OL-PVP19, OL-PVP20, OL-PVP30, OL-PVP31A, OL-PVP31B, OL-PVP32, OL-PVP33, OL-PVP34A, OL-PVP34B, OL-HP1, OL-HP2, OL-HP3 and OL-HP4 was measured in summer 2010. The length of PP-holes was between 12 and 14 m, and the test sections (1 m) are located in the bedrock. PVP-tubes have an average length between 3..11 m up to c. 17 m, and the test sections (mostly 2 m) are located in the overburden. The measurements were carried out using the slug-test technique with renewed equipment. In the slug-test, the hydraulic head in the borehole is abruptly changed either by pouring water into the borehole or by lowering the pressure sensor. The hydraulic conductivity is interpreted from the recovery of the water level. This report presents the field measurements and their interpretation. The interpretation has been done using the Hvorslev's method, and for reference, conductivity has also been calculated according to Thiem's equation. According to the results, hydraulic conductivity in PP-holes ranges from 10-9 m/s to 10-6 m/s and in PVP-tubes from 10-8 m/s to 10-4 m/s. The observed range is quite similar as in the previous measurements in 2002 and 2004-2009. In general, the results are consistent with the results obtained in earlier measurements. In OL-PVP14, the earlier observed lowering trend of the conductivity seems to have stabilized. Also, the results agree relatively well with hydraulic conductivity interpreted from the pre-pumping done in connection with the groundwater sampling. (orig.)

  17. Slug-Tests in PP- and PVP-holes at Olkiluoto in 2007

    International Nuclear Information System (INIS)

    Keskitalo, K.

    2008-05-01

    As part of the program for the final disposal of the nuclear fuel waste, Posiva Oy investigates the hydrological conditions at the Olkiluoto island. The hydraulic conductivity in the shallow holes OL-PP9, OL-PP36, OL-PP39, OL-PVP3A, OL-PVP3B, OL-PVP4A, OL-PVP4B, OL-PVP6A, OL-PVP6B, OL-PVP7A, OL-PVP8A, OL-PVP8B, OL-PVP9A, OL-PVP9B, OL-PVP10A, OL-PVP10B, OL-PVP11, OL-PVP12, OL-PVP13, OL-PVP14, OL-PVP17, OL-PVP18A, OL-PVP18B, OL-PVP19 and OL-PVP20 was measured in summer 2007. The length of PP-holes varies between 12 and 15 m, and the test sections (1 m) are located in the bedrock. PVP-tubes have an average length between 3 - 9 m up to 17 m, and the test sections (mostly 2 m) are located in the overburden. The measurements were done using the slug-test technique. In the slug-test, the hydraulic head in the borehole is abruptly changed either by pouring water into the borehole or by lowering the pressure sensor. The conductivity is interpreted based on the recovery of the water level. This report presents the field measurements and their interpretation. The interpretation has been done using the Hvorslev's method, and for reference, conductivity has also been calculated according to Thiem's equation. According to the results, hydraulic conductivity in PP-holes ranges from 10-9 m/s to 10-6 m/s and in PVP-tubes from 10-8 m/s to 10-4 m/s. The range is similar as observed in measurements of years 2002, 2004, 2005 and 2006. In general, the results are consistent with the results obtained in earlier measurements. Some exceptions exist in OL-PVP6B, where the conductivity is higher than in the earlier measurements. In OL-PVP14, there seems to be a lowering trend of the conductivity. In OL-PP9, the conductivity in test section 5.3 - 6.3 m in 2007 was about one order of magnitude lower than in 2005 but the results from 2007, 2006, and 2002 correlate well in that section. Also, the results agree with hydraulic conductivity interpreted from the pre-pumping done in connection with

  18. Slug-tests in PP- and PVP-holes at Olkiluoto in 2008

    International Nuclear Information System (INIS)

    Keskitalo, K.

    2009-02-01

    As part of the program for the final disposal of the nuclear fuel waste, Posiva Oy investigates the hydrological conditions at the Olkiluoto island. The hydraulic conductivity in the shallow holes OL-PP36, OL-PP39, OL-PVP4A, OL-PVP4B, OL-PVP6A, OL-PVP6B, OL-PVP14, OL-PVP21, OL-PVP22, OL-PVP23, OL-PVP24, OL-PVP25, OL-PVP26, OL-PVP27, OL-PVP28, OL-PVP29, OL-HP1, OL-HP2 and OL-HP4 was measured in summer 2008. The length of PP-holes was between 12 and 14 m, and the test sections (1 m) are located in the bedrock. PVP-tubes have an average length between 3 - 11 m, and the test sections (mostly 2 m) are located in the overburden. The measurements were done using the slug-test technique. In the slug-test, the hydraulic head in the borehole is abruptly changed either by pouring water into the borehole or by lowering the pressure sensor. The hydraulic conductivity is interpreted from the recovery of the water level. This report presents the field measurements and their interpretation. The interpretation has been done using the Hvorslev's method, and for reference, conductivity has also been calculated according to Thiem's equation. According to the results, hydraulic conductivity in PP-holes ranges from 10 -9 m/s to 10 -6 m/s and in PVP-tubes from 10 -8 m/s to 10 -5 m/s. The observed range is similar as in the previous measurements in 2002 and 2004 - 2007. In general, the results are consistent with the results obtained in earlier measurements. In OL-PVP14, there seems to be a lowering trend of the conductivity. In OL-PVP4A the results seem to have slight increase year after year. Also, the results agree with hydraulic conductivity interpreted from the pre-pumping done in connection with the groundwater sampling or installation of observation tubes. (orig.)

  19. Slug-tests in PP- and PVP-holes at Olkiluoto in 2009

    International Nuclear Information System (INIS)

    Isola, O.

    2010-11-01

    As part of the program for the final disposal of the nuclear fuel waste, Posiva Oy investigates the hydrological conditions at the Olkiluoto Island. The hydraulic conductivity in the shallow holes OL-PP36, OL-PP39, OL-PVP4A, OL-PVP4B, OL-PVP6A, OL-PVP6B, OL-PVP14, OL-PVP30, OL-PVP31A, OL-PVP31B, OLPVP32, OL-PVP33, OL-PVP34A, OL-PVP34B, OL-HP1, OL-HP2, OL-HP3 and OLHP4 was measured in summer 2009. The length of PP-holes was between 12 and 14 m, and the test sections (1 m) are located in the bedrock. PVP-tubes have an average length between 3 - 11 m, and the test sections (mostly 2 m) are located in the overburden. The measurements were done using the slug-test technique. In the slug-test, the hydraulic head in the borehole is abruptly changed either by pouring water into the borehole or by lowering the pressure sensor. The hydraulic conductivity is interpreted from the recovery of the water level. This report presents the field measurements and their interpretation. The interpretation has been done using the Hvorslev's method, and for reference, conductivity has also been calculated according to Thiem's equation. According to the results, hydraulic conductivity in PP-holes ranges from 10 -1 0 m/s to 10 -6 m/s and in PVP-tubes from 10 -8 m/s to 10 -5 m/s. The observed range is quite similar as in the previous measurements in 2002 and 2004 - 2008. In general, the results are consistent with the results obtained in earlier measurements. In OL-PVP14, there seems to be a lowering trend of the conductivity. Also, the results agree relatively well with hydraulic conductivity interpreted from the pre-pumping done in connection with the groundwater sampling. (orig.)

  20. An Evaluation of the Bouwer and Rice Method of Slug Test Analysis

    Science.gov (United States)

    Brown, David L.; Narasimhan, T. N.; Demir, Z.

    1995-05-01

    The method of Bouwer and Rice (1976) for analyzing slug test data is widely used to estimate hydraulic conductivity (K). Based on steady state flow assumptions, this method is specifically intended to be applicable to unconfined aquifers. Therefore it is of practical value to investigate the limits of accuracy of the K estimates obtained with this method. Accordingly, using a numerical model for transient flow, we evaluate the method from two perspectives. First, we apply the method to synthetic slug test data and study the error in estimated values of K. Second, we analyze the logical basis of the method. Parametric studies helped assess the role of the effective radius parameter, specific storage, screen length, and well radius on the estimated values of K. The difference between unconfined and confined systems was studied via conditions on the upper boundary of the flow domain. For the cases studied, the Bouwer and Rice analysis was found to give good estimates of K, with errors ranging from 10% to 100%. We found that the estimates of K were consistently superior to those obtained with Hvorslev's (1951) basic time lag method. In general, the Bouwer and Rice method tends to underestimate K, the greatest errors occurring in the presence of a damaged zone around the well or when the top of the screen is close to the water table. When the top of the screen is far removed from the upper boundary of the system, no difference is manifest between confined and unconfined conditions. It is reasonable to infer from the simulated results that when the screen is close to the upper boundary, the results of the Bouwer and Rice method agree more closely with a "confined" idealization than an "unconfined" idealization. In effect, this method treats the aquifer system as an equivalent radial flow permeameter with an effective radius, Re, which is a function of the flow geometry. Our transient simulations suggest that Re varies with time and specific storage. Thus the effective

  1. The Slug and Churn Turbulence Characteristics of Oil-Gas-Water Flows in a Vertical Small Pipe

    Science.gov (United States)

    Liu, Weixin; Han, Yunfeng; Wang, Dayang; Zhao, An; Jin, Ningde

    2017-08-01

    The intention of the present study was to investigate the slug and churn turbulence characteristics of a vertical upward oil-gas-water three-phase flow. We firstly carried out a vertical upward oil-gas-water three-phase flow experiment in a 20-mm inner diameter (ID) pipe to measure the fluctuating signals of a rotating electric field conductance sensor under different flow patterns. Afterwards, typical flow patterns were identified with the aid of the texture structures in a cross recurrence plot. Recurrence quantitative analysis and multi-scale cross entropy (MSCE) algorithms were applied to investigate the turbulence characteristics of slug and churn flows with the varying flow parameters. The results suggest that with cross nonlinear analysis, the underlying dynamic characteristics in the evolution from slug to churn flow can be well understood. The present study provides a novel perspective for the analysis of the spatial-temporal evolution instability and complexity in oil-gas-water three-phase flow.

  2. An extension of theoretical analysis for the onset of slugging criterion in horizontal stratified air-water countercurrent flow

    International Nuclear Information System (INIS)

    Lee, Byung Ryung

    1997-02-01

    This paper presents an experimental and theoretical investigation of interfacial friction factor, wave height and transition criterion from wavy to slug flow in a long horizontal air-water countercurrent stratified flow condition. A series of experiments have been conducted in adiabatic countercurrent stratified flow with the round pipe and rectangular duct test section to develop the interfacial friction factor and the criterion of onset of slugging in horizontal air-water countercurrent stratified flow. An adiabatic semi-empirical correlation for interfacial friction factor has been developed based on the surface roughness concept. A comparison of the measured data in this study and of other investigators with the predictions of the present correlation shows that the agreement is within ±30% error, and that the present correlation is applicable to a broader range of water flow rate than the correlations of previous investigators. The theories which can calculate the wave height and criteria of onset of slug flow in a stratified wavy flow regime have been developed based on the concept of total energy conservation and also wave theory. This theoretical criteria agree better with the measured data than the other criteria available in the literature, but the criteria range about 92∼107% of the measured data. An empirical formula for the criterion has been also developed and compared with the formula in the literatures. Comparison between the measured data and the predictions of the present theory shows that the agreement is within ±8%

  3. Analytic solutions to linear, time-dependent fission product deposition models for isothermal laminar, slug, or multiregion flow conditions

    International Nuclear Information System (INIS)

    Durkee, J.W. Jr.

    1983-01-01

    The time-dependent convective-diffusion equation with radioactive decay is solved analytically in axisymmetric cylindrical geometry for laminar and slug velocity profiles under isothermal conditions. Concentration dependent diffusion is neglected. The laminar flow solution is derived using the method of separation of variables and Frobenius' technique for constructing a series expansion about a regular singular point. The slug flow multiregion solution is obtained using the method of separation of variables. The Davidon Variable Metric Minimization algorithm is used to compute the coupling coefficients. These solutions, which describe the transport of fission products in a flowing stream, are then used to determine the concentration of radioactive material deposited on a conduit wall using a standard mass transfer model. Fission product deposition measurements for five diffusion tubes in a Fort St. Vrain High-Temperature Gas-Cooled reactor plateout probe are analyzed. Using single region slug and laminar models, the wall mass transfer coefficients, diffusion coefficients, and inlet concentrations are determined using least squares analysis. The diffusion coefficients and inlet concentrations are consistent between tubes. The derived diffusion coefficients and wall mass transfer coefficients are in relative agreement with known literature values

  4. Opisthobranchia (Mollusca, Gastropoda – more than just slimy slugs. Shell reduction and its implications on defence and foraging

    Directory of Open Access Journals (Sweden)

    Wägele Heike

    2005-02-01

    Full Text Available Abstract Background In general shell-less slugs are considered to be slimy animals with a rather dull appearance and a pest to garden plants. But marine slugs usually are beautifully coloured animals belonging to the less-known Opisthobranchia. They are characterized by a large array of interesting biological phenomena, usually related to foraging and/or defence. In this paper our knowledge of shell reduction, correlated with the evolution of different defensive and foraging strategies is reviewed, and new results on histology of different glandular systems are included. Results Based on a phylogeny obtained by morphological and histological data, the parallel reduction of the shell within the different groups is outlined. Major food sources are given and glandular structures are described as possible defensive structures in the external epithelia, and as internal glands. Conclusion According to phylogenetic analyses, the reduction of the shell correlates with the evolution of defensive strategies. Many different kinds of defence structures, like cleptocnides, mantle dermal formations (MDFs, and acid glands, are only present in shell-less slugs. In several cases, it is not clear whether the defensive devices were a prerequisite for the reduction of the shell, or reduction occurred before. Reduction of the shell and acquisition of different defensive structures had an implication on exploration of new food sources and therefore likely enhanced adaptive radiation of several groups.

  5. Coupled fluid/structure response of a reactor cover to slug impact loading

    International Nuclear Information System (INIS)

    Smith, B.L.; Saurer, G.; Wanner, R.; Palsson, H.

    1983-05-01

    The response of an LMFBR roof structure to slug impact loads is investigated using a combined 2D and 3D approach based on the containment code SEURBNUK and the finite element structure code ADINA. A specimen roof design of box-type construction with concrete infill is adopted for the study, with dimensions appropriate to a commercial-sized fast reactor of the 'pool' type. Provision is made in the model for the location of the major roof penetrations, and the roof annulus is closed in the central section by a rigid, but movable plug concentric with the axis of symmetry. An interface between the codes SEURBNUK and ADINA is made possible by defining a 2D substitute roof model with material properties chosen to match the principal response characteristics of the detailed model. The SEURBNUK code, recently extended to account for coupling of roof loading and roof response, uses the 2D model, incorporated in an appropriate reactor geometry, to examine the fluid-structure interactions and to supply roof pressure loadings for the ADINA runs. A strategy for cross-checking the structural equivalence of the 2D and 3D roof models is developed, and this operates in parallel with the loading and response computations. The first exploratory SEURBNUK calculations are described in which the roof is represented by a simple homogeneous plate. (Auth.)

  6. Influence of vapor phase turbulent stress to the onset of slugging in a horizontal pipe

    International Nuclear Information System (INIS)

    Park, Jee Won

    1995-01-01

    An influence of the vapor phase turbulent stress(i, e., the two-phase Reynolds stress)to the characteristics of two-phase system in a horizontal pipe has been theoretically investigated. The average two-fluid model has been constituted with closure relations for stratified flow in a horizontal pipe. A vapor phase turbulent stress model for the regular interface geometry has been included. It is found that the second order waves propagate in opposite direction with almost the same speed in the moving frame of reference of the liquid phase velocity. Using the well-posedness limit of the two-phase system, the dispersed-stratified flow regime boundary has been modeled. Two-phase Froude number has been found to be a convenient parameter in quantifying the onset of slugging as a function of the global void fraction. The influence of the vapor phase turbulent stress was found to stabilize the flow stratification. 4 figs., 12 refs. (Author)

  7. Slug/SNAI2 regulates cell proliferation and invasiveness of metastatic prostate cancer cell lines.

    Science.gov (United States)

    Emadi Baygi, Modjtaba; Soheili, Zahra-Soheila; Essmann, Frank; Deezagi, Abdolkhaleg; Engers, Rainer; Goering, Wolfgang; Schulz, Wolfgang A

    2010-08-01

    Many metastatic cancers recapitulate the epithelial-to-mesenchymal transition (EMT) resulting in enhanced cell motility and invasiveness. The EMT is regulated by several transcription factors, including the zinc finger protein SNAI2, also named Slug, which appears to exert additional functions during development and cancer progression. We have studied the function of SNAI2 in prostate cancer cells. Quantitative RT-PCR analysis showed strong SNAI2 expression particularly in the PC-3 and PC3-16 prostate carcinoma cell lines. Knockdown of SNAI2 by specific siRNA induced changes in EMT markers and inhibited invasion of both cell lines into a matrigel matrix. SNAI2 siRNA-treated cells did not tolerate detachment from the culture plates, likely at least in part due to downregulation of integrin alpha6beta4. SNAI2 knockdown disturbed the microtubular and actin cytoskeletons, especially severely in PC-3 cells, resulting in grossly enlarged, flattened, and sometimes multinuclear cells. Knockdown also decreased cell proliferation, with a prominent G0/G1 arrest in PC3-16. Together, our data imply that SNAI2 exerts strong effects on the cytoskeleton and adhesion of those prostate cancer cells that express it and is necessary for their proliferation and invasiveness.

  8. Quasi-3D Modelling of Two-Phase Slug Flow in Pipes

    Directory of Open Access Journals (Sweden)

    S. Mo

    2014-03-01

    Full Text Available In this paper, we present progress obtained by the Quasi 3-Dimensional (Q3D model for pipe flows. This model is based on a multi-fluid multi-field formulation with construction and tracking of the large-scale interfaces (LSIs. The computational time is significantly reduced compared to full 3D by using a specially adopted slice-averaging technique. However, the slice-averaging generates new terms in the model equations. These terms are related to important mechanisms such as wall shear stress and turbulence production at side walls. We present some basic performance tests of the Q3D model, including single phase wall friction and the velocities of single Taylor bubbles at inclinations ranging from horizontal to vertical. Finally we report the performance of the model for slug flow in horizontal and 10° inclined pipes. The model reproduces the experimental data satisfactorily for both cases in a very short simulation time compared to full 3D.

  9. Neuronal responses to water flow in the marine slug tritonia diomedea

    Directory of Open Access Journals (Sweden)

    Jeffrey Blackwell

    2005-07-01

    Full Text Available The marine slug Tritonia diomedea must rely on its ability to touch and smell in order to navigate because it is blind. The primary factor that influences its crawling direction is the direction of water flow (caused by tides in nature. The sensory cells that detect flow and determine flow direction have not been identified. The lateral branch of Cerebral Nerve 2 (latCeN2 has been identified as the nerve that carries sensory axons to the brain from the flow receptors inthe oral tentacles. Backfilling this nerve to the brain resulted in the labeling of a number of cells located throughout the brain. Most of the labeled cells are concentrated in the cerebral ganglion where the nerve enters the brain. The medial and lateral branches of CeN2 were backfilled for comparison of the pattern of cells from each nerve. A map of the cells innervated by latCeN2 reveals the location of the stained cells. Extracellular recording from latCeN2 revealed its involvement in the detection of water flow and orientation. The nerve becomes active in response to water flow stimulation. Intracellular recordings of the electrical activity of these cells in a live animal will be the next step to determine if these cells are the flow receptors.

  10. Modification of a compressor performance test bench for liquid slugging observation in refrigeration compressors

    Science.gov (United States)

    Ola, Max; Thomas, Christiane; Hesse, Ullrich

    2017-08-01

    Compressor performance test procedures are defined by the standard DIN EN 13771, wherein a variety of possible calorimeter and flow rate measurement methods are suggested. One option is the selection of two independent measurement methods. The accuracies of both selected measurement methods are essential. The second option requires only one method. However the measurement accuracy of the used device has to be verified and recalibrated on a regular basis. The compressor performance test facility at the Technische Universitaet Dresden uses a calibrated flow measurement sensor, a hot gas bypass and a mixed flow heat exchanger. The test bench can easily be modified for tests of various compressor types at different operating ranges and with various refrigerants. In addition, the modified test setup enables the investigation of long term liquid slug and its effects on the compressor. The modification comprises observational components, adjustments of the control system, safety measures and a customized oil recirculation system for compressors which do not contain an integrated oil sump or oil level regulation system. This paper describes the setup of the test bench, its functional principle, the key modifications, first test results and an evaluation of the energy balance.

  11. Two-fluid model for transient analysis of slug flow in oil wells

    International Nuclear Information System (INIS)

    Cazarez-Candia, O.; Benitez-Centeno, O.C.; Espinosa-Paredes, G.

    2011-01-01

    In this work it is presented a transient, one-dimensional, adiabatic model for slug flow simulation, which appears when liquid (mixture of oil and water) and gas flow simultaneously through pipes. The model is formed by space and time averaged conservation equations for mass, momentum and energy for each phase, the numerical solution is based on the finite difference technique in the implicit scheme. Velocity, pressure, volumetric fraction and temperature profiles for both phases were predicted for inclination angles from the horizontal to the vertical position (unified model) and ascendant flow. Predictions from the model were validated using field data and ten correlations commonly used in the oil industry. The effects of gas heating or cooling, due to compression and expansion processes, on the predictions and numerical stability, were studied. It was found that when these effects are taken into account, a good behavior of temperature predictions and numerical stability are obtained. The model presents deviations lower than 14% regarding field data and it presents better predictions than most of the correlations.

  12. Turning snails into slugs: induced body plan changes and formation of an internal shell.

    Science.gov (United States)

    Osterauer, Raphaela; Marschner, Leonie; Betz, Oliver; Gerberding, Matthias; Sawasdee, Banthita; Cloetens, Peter; Haus, Nadine; Sures, Bernd; Triebskorn, Rita; Köhler, Heinz-R

    2010-01-01

    The archetypal body plan of conchiferan molluscs is characterized by an external calcareous shell, though internalization of shells has evolved independently in a number of molluscan clades, including gastropod families. In gastropods, the developmental process of torsion is regarded as a hallmark that is associated with a new anatomical configuration. This configuration is present in extant prosobranch gastropod species, which predominantly bear external shells. Here, we show that short-term exposure to platinum during development uncouples at least two of the processes associated with torsion of the freshwater snail Marisa cornuarietis. That is, the anus of the treated snails is located anteriorly, but the gill and the designated mantle tissue remains in a posterior location, thus preventing the formation of an external shell. In contrast to the prosobranchian archetype, platinum treatment results in the formation of a posterior gill and a cone-shaped internal shell, which persists across the lifetime. This first finding of artificially induced snail-slug conversion was also seen in the pulmonate snail Planorbarius corneus and demonstrates that selective alteration of embryonic key processes can result in fundamental changes of an existing body plan and-if altered regulation is inherited-may give rise to a new one. © 2010 Wiley Periodicals, Inc.

  13. Fluid Mechanics of Taylor Bubbles and Slug Flows in Vertical Channels

    International Nuclear Information System (INIS)

    Anglart, Henryk; Podowski, Michael Z.

    2002-01-01

    Fluid mechanics of Taylor bubbles and slug flows is investigated in vertical, circular channels using detailed, three-dimensional computational fluid dynamics simulations. The Volume of Fluid model with the interface-sharpening algorithm, implemented in the commercial CFX4 code, is used to predict the shape and velocity of Taylor bubbles moving along a vertical channel. Several cases are investigated, including both a single Taylor bubble and a train of bubbles rising in water. It is shown that the potential flow solution underpredicts the water film thickness around Taylor bubbles. Furthermore, the computer simulations that are performed reveal the importance of properly modeling the three-dimensional nature of phenomena governing the motion of Taylor bubbles. Based on the present results, a new formula for the evaluation of bubble shape is derived. Both the shape of Taylor bubbles and the bubble rise velocity predicted by the proposed model agree well with experimental observations. Furthermore, the present model shows good promise in predicting the coalescence of Taylor bubbles

  14. Two-fluid model for transient analysis of slug flow in oil wells

    Energy Technology Data Exchange (ETDEWEB)

    Cazarez-Candia, O., E-mail: ocazarez@imp.mx [Instituto Mexicano del Petroleo, Eje central Lazaro Cardenas No. 152, Col. San Bartolo Atepehuacan, Mexico D.F. 07730 (Mexico); Instituto Tecnologico de Zacatepec, Depto. de Metal-Mecanica, Calzada Tecnologico, No. 27, Zacatepec, Morelos 62780 (Mexico); Benitez-Centeno, O.C. [Centro Nacional de Investigacion y Desarrollo Tecnologico, Depto. de Mecanica, Interior Internado Palmira s/n, Col. Palmira, Cuernavaca, Morelos 62490 (Mexico); Espinosa-Paredes, G. [Area de Ingenieria en Recursos Energeticos, Universidad Autonoma Metropolitana-Iztapalapa, Av San Rafael Atlixco No 186, Col. Vicentina 55-534, Mexico D.F. 09340 (Mexico)

    2011-06-15

    In this work it is presented a transient, one-dimensional, adiabatic model for slug flow simulation, which appears when liquid (mixture of oil and water) and gas flow simultaneously through pipes. The model is formed by space and time averaged conservation equations for mass, momentum and energy for each phase, the numerical solution is based on the finite difference technique in the implicit scheme. Velocity, pressure, volumetric fraction and temperature profiles for both phases were predicted for inclination angles from the horizontal to the vertical position (unified model) and ascendant flow. Predictions from the model were validated using field data and ten correlations commonly used in the oil industry. The effects of gas heating or cooling, due to compression and expansion processes, on the predictions and numerical stability, were studied. It was found that when these effects are taken into account, a good behavior of temperature predictions and numerical stability are obtained. The model presents deviations lower than 14% regarding field data and it presents better predictions than most of the correlations.

  15. Activity of invasive slug Limax maximus in relation to climate conditions based on citizen's observations and novel regularization based statistical approaches.

    Science.gov (United States)

    Morii, Yuta; Ohkubo, Yusaku; Watanabe, Sanae

    2018-05-13

    Citizen science is a powerful tool that can be used to resolve the problems of introduced species. An amateur naturalist and author of this paper, S. Watanabe, recorded the total number of Limax maximus (Limacidae, Pulmonata) individuals along a fixed census route almost every day for two years on Hokkaido Island, Japan. L. maximus is an invasive slug considered a pest species of horticultural and agricultural crops. We investigated how weather conditions were correlated to the intensity of slug activity using for the first time in ecology the recently developed statistical analyses, Bayesian regularization regression with comparisons among Laplace, Horseshoe and Horseshoe+ priors for the first time in ecology. The slug counts were compared with meteorological data from 5:00 in the morning on the day of observation (OT- and OD-models) and the day before observation (DBOD-models). The OT- and OD-models were more supported than the DBOD-models based on the WAIC scores, and the meteorological predictors selected in the OT-, OD- and DBOD-models were different. The probability of slug appearance was increased on mornings with higher than 20-year-average humidity (%) and lower than average wind velocity (m/s) and precipitation (mm) values in the OT-models. OD-models showed a pattern similar to OT-models in the probability of slug appearance, but also suggested other meteorological predictors for slug activities; positive effect of solar radiation (MJ) for example. Five meteorological predictors, mean and highest temperature (°C), wind velocity (m/s), precipitation amount (mm) and atmospheric pressure (hPa), were selected as the effective factors for the counts in the DBOD-models. Therefore, the DBOD-models will be valuable for the prediction of slug activity in the future, much like a weather forecast. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. Decreased expression of MUC1 induces apoptosis and inhibits migration in pancreatic cancer PANC-1 cells via regulation of Slug pathway.

    Science.gov (United States)

    Zhao, Ping; Meng, Meng; Xu, Bin; Dong, Aiping; Ni, Guangzhen; Lu, Lianfang

    2017-12-06

    MUC1, a membrane tethered mucin glycoprotein, is overexpressed in > 60% of human pancreatic cancers (PCs), and is associated with poor prognosis and enhanced metastasis. Here, we report the effect of silencing MUC1 expression on the growth, migration and invasive ability of pancreatic cancer cells, and explored its mechanisms. We observed that siRNA mediated suppression of the MUC1 expression significantly reduced invasive and migrative capability and induced apoptosis of the pancreatic cancer PANC-1 cells. We found that Slug was inhibited in the MUC1 siRNA transfected PANC-1 cells (MUC1 siRNA/PANC-1 cells). Expression of PUMA and E-cadherin was increased in the MUC1 siRNA/PANC-1 cells. PANC-1 cells overexpressing full long Slug gene (when transfected with Slug cDNA plasmid) significantly inhibited PUMA and E-cadherin expression in the MUC1 siRNA/PANC-1 cells. Silencing PUMA expression inhibited apoptosis in the MUC1 siRNA transfected PANC-1 cells (MUC1 siRNA/PANC-1 cells). Silencing E-cadherin expression restored the invasion and migration ability in the MUC1 siRNA/PANC-1 cells. We therefore concluded that silencing MUC1 expression inhibited migration and invasion, and induced apoptosis of PANC-1 cells via downregulation of Slug and upregulation of Slug dependent PUMA and E-cadherin expression. MUC1 could serve as a potential therapeutic target in pancreatic cancer.

  17. The evaluation of the local tolerance of vaginal formulations containing dapivirine using the Slug Mucosal Irritation test and the rabbit vaginal irritation test.

    Science.gov (United States)

    Dhondt, Marijke M M; Adriaens, Els; Roey, Jens Van; Remon, Jean Paul

    2005-08-01

    The purpose of this study was to evaluate the local tolerance of vaginal gels (three gels containing dapivirine, the placebo gel, and Conceptrol) with the Slug Mucosal Irritation test and to compare the results with those of the rabbit vaginal irritation test. The irritation potential on the slug mucosa was assessed by the mucus production caused by a repeated treatment for 5 successive days. Additionally, membrane damage was estimated by the protein and enzyme release. By means of a classification prediction model the formulations were classified into four irritation classes. The effect of a 10-day intravaginal application of the gels on the rabbit vaginal and cervical mucosa was evaluated by means of macroscopic and microscopic examination. The placebo and dapivirine gels induced no irritation of the slug mucosa (low mucus production and protein release, no enzyme release) and no vaginal or cervical irritation in rabbits. Conceptrol caused severe irritation of the slug mucosa (increased mucus production, protein release, and enzyme release) and irritation of the rabbit vagina and cervix. The results obtained with the Slug Mucosal Irritation test were comparable to those of the rabbit vaginal irritation test.

  18. 3-dimensional Simulation of an Air-lift Pump from Bubbly to Slug Flow

    Energy Technology Data Exchange (ETDEWEB)

    Jo, Hongrae; Jo, Daeseong [Kyungpook National Univ, Daegu (Korea, Republic of)

    2015-10-15

    The air-lift pump has been used in various applications with its merit that it can pump up without any moving parts. E.g. coffee percolator, petroleum industry, suction dredge, OTEC i.e. ocean thermal energy conversion and so on. By the merit, it has high durability for high temperature water or vapor, and fluid-solid mixture like waste water, muddy water and crude, which cause problems when it's pumped up with general pumps. In this regard, the air-lift pump has been one of the most desirable technology. A typical air-lift pump configuration is illustrated in Figure 01. The principle of this pump is very simple. When air is injected from the injector at bottom of a submerged tube, i.e., air bubbles are suspended in the liquid, the average density of the mixture in the tube is less than that of the surrounding fluid in the reservoir. Then hydrostatic pressure over the length of the tube is decreased. This buoyancy force causes a pumping action. The comparison of the simulated results, experimental result, and theoretical result is been able by data shown as Figure 04. They have similar trends but they also have a little differences because there are some limits of simulating the flow regimes. At the different flow condition, different coefficients for friction factor or pressure drop should be used, but this simulation uses a laminar condition and the theoretical equations are valid only for slug regime where the air flow rate is lower than the other regimes. From these causes, the differences has arisen, and difference comes bigger as the air flow rate increases, i.e., becoming annular flow regime or churn flow regime.

  19. Exploring the IMF of star clusters: a joint SLUG and LEGUS effort

    Science.gov (United States)

    Ashworth, G.; Fumagalli, M.; Krumholz, M. R.; Adamo, A.; Calzetti, D.; Chandar, R.; Cignoni, M.; Dale, D.; Elmegreen, B. G.; Gallagher, J. S., III; Gouliermis, D. A.; Grasha, K.; Grebel, E. K.; Johnson, K. E.; Lee, J.; Tosi, M.; Wofford, A.

    2017-08-01

    We present the implementation of a Bayesian formalism within the Stochastically Lighting Up Galaxies (slug) stellar population synthesis code, which is designed to investigate variations in the initial mass function (IMF) of star clusters. By comparing observed cluster photometry to large libraries of clusters simulated with a continuously varying IMF, our formalism yields the posterior probability distribution function (PDF) of the cluster mass, age and extinction, jointly with the parameters describing the IMF. We apply this formalism to a sample of star clusters from the nearby galaxy NGC 628, for which broad-band photometry in five filters is available as part of the Legacy ExtraGalactic UV Survey (LEGUS). After allowing the upper-end slope of the IMF (α3) to vary, we recover PDFs for the mass, age and extinction that are broadly consistent with what is found when assuming an invariant Kroupa IMF. However, the posterior PDF for α3 is very broad due to a strong degeneracy with the cluster mass, and it is found to be sensitive to the choice of priors, particularly on the cluster mass. We find only a modest improvement in the constraining power of α3 when adding Hα photometry from the companion Hα-LEGUS survey. Conversely, Hα photometry significantly improves the age determination, reducing the frequency of multi-modal PDFs. With the aid of mock clusters, we quantify the degeneracy between physical parameters, showing how constraints on the cluster mass that are independent of photometry can be used to pin down the IMF properties of star clusters.

  20. Cross-linking by protein oxidation in the rapidly setting gel-based glues of slugs

    Science.gov (United States)

    Bradshaw, Andrew; Salt, Michael; Bell, Ashley; Zeitler, Matt; Litra, Noelle; Smith, Andrew M.

    2011-01-01

    SUMMARY The terrestrial slug Arion subfuscus secretes a glue that is a dilute gel with remarkable adhesive and cohesive strength. The function of this glue depends on metals, raising the possibility that metal-catalyzed oxidation plays a role. The extent and time course of protein oxidation was measured by immunoblotting to detect the resulting carbonyl groups. Several proteins, particularly one with a relative molecular mass (Mr) of 165×103, were heavily oxidized. Of the proteins known to distinguish the glue from non-adhesive mucus, only specific size variants were oxidized. The oxidation appears to occur within the first few seconds of secretion. Although carbonyls were detected by 2,4-dinitrophenylhydrazine (DNPH) in denatured proteins, they were not easily detected in the native state. The presence of reversible cross-links derived from carbonyls was tested for by treatment with sodium borohydride, which would reduce uncross-linked carbonyls to alcohols, but stabilize imine bonds formed by carbonyls and thus lead to less soluble complexes. Consistent with imine bond formation, sodium borohydride led to a 20–35% decrease in the amount of soluble protein with a Mr of 40–165 (×103) without changing the carbonyl content per protein. In contrast, the nucleophile hydroxylamine, which would competitively disrupt imine bonds, increased protein solubility in the glue. Finally, the primary amine groups on a protein with a Mr of 15×103 were not accessible to acid anhydrides. The results suggest that cross-links between aldehydes and primary amines contribute to the cohesive strength of the glue. PMID:21525316

  1. Characteristic behavior of bubbles and slugs in transient two-phase flow using image-processing method

    International Nuclear Information System (INIS)

    Goto, Shoji; Ishizaki, Yasuo; Ohashi, Hirotada; Akiyama, Mamoru

    1995-01-01

    Simulation of transient two-phase flow has been performed by solving transient hydrodynamic equations. However, constitution relations used in this simulation are primarily based on steady-state experimental results. Thus it is important to understand the transient behavior of bubbles and slugs, in particular, transient behavior of the void fraction, the interfacial area and the flow pattern, to confirm the applicability of the present simulation method and to advance two-phase flow simulation further. The present study deals with measurement of transient two-phase flow. We have measured local and instantaneous void fractions using imaging techniques, and compared the experimental data with simulation results. (author)

  2. Borehole Logging and Slug Tests for Evaluating the Applicability of Electrical Resistivity Tomography for Groundwater Exploration in Nampula Complex, Mozambique

    Directory of Open Access Journals (Sweden)

    Farisse Chirindja

    2017-02-01

    Full Text Available In Nampula province, Mozambique, there is a high number of water wells considered as having failed for having too low a pumping yield. Two Electrical Resistivity Tomography (ERT measurement campaigns were conducted in the area for evaluating the reasons of failures. However, in some cases it was difficult to verify and interpret the ERT results by only using the inadequate lithological description presented in drilling reports. In this paper the integration of borehole logging and slug testing is presented as a solution to add more information and to enhance the interpretation of ERT models. The borehole logging tool measured resistivity, magnetic susceptibility and natural gamma. The logging results proved that the ERT models are accurate in estimating the resistivity for basement (>1400 Ωm, fractured layer (220–1400 Ωm, semi-weathered layer with clay accumulation (10–220 Ωm, and weathered and leached layer (220–2700 Ωm. The slug testing gave results of high hydraulic conductivity (K values where the ERT indicates well-developed weathered and fractured layers, and low K values where these are less developed. The borehole interpretation can be extrapolated using the ERT model to give a geometric characterization of the aquifer. Therefore, the implementation of the ERT method in groundwater exploration is encouraged.

  3. Human cancer cells express Slug-based epithelial-mesenchymal transition gene expression signature obtained in vivo

    International Nuclear Information System (INIS)

    Anastassiou, Dimitris; Rumjantseva, Viktoria; Cheng, Weiyi; Huang, Jianzhong; Canoll, Peter D; Yamashiro, Darrell J; Kandel, Jessica J

    2011-01-01

    The biological mechanisms underlying cancer cell motility and invasiveness remain unclear, although it has been hypothesized that they involve some type of epithelial-mesenchymal transition (EMT). We used xenograft models of human cancer cells in immunocompromised mice, profiling the harvested tumors separately with species-specific probes and computationally analyzing the results. Here we show that human cancer cells express in vivo a precise multi-cancer invasion-associated gene expression signature that prominently includes many EMT markers, among them the transcription factor Slug, fibronectin, and α-SMA. We found that human, but not mouse, cells express the signature and Slug is the only upregulated EMT-inducing transcription factor. The signature is also present in samples from many publicly available cancer gene expression datasets, suggesting that it is produced by the cancer cells themselves in multiple cancer types, including nonepithelial cancers such as neuroblastoma. Furthermore, we found that the presence of the signature in human xenografted cells was associated with a downregulation of adipocyte markers in the mouse tissue adjacent to the invasive tumor, suggesting that the signature is triggered by contextual microenvironmental interactions when the cancer cells encounter adipocytes, as previously reported. The known, precise and consistent gene composition of this cancer mesenchymal transition signature, particularly when combined with simultaneous analysis of the adjacent microenvironment, provides unique opportunities for shedding light on the underlying mechanisms of cancer invasiveness as well as identifying potential diagnostic markers and targets for metastasis-inhibiting therapeutics

  4. Numerical simulation of two-phase slug flow with liquid carryover in different diameter ratio T-junction

    Science.gov (United States)

    Pao, W.; Hon, L.; Saieed, A.; Ban, S.

    2017-10-01

    A smaller diameter conduit pointing at 12 o’clock position is typically hot-tapped to a horizontal laying production header in offshore platform to tap produced gas for downstream process train. This geometric feature is commonly known as T-junction. The nature of multiphase fluid splitting at the T-junction is a major operational challenge due to unpredictable production environment. Often, excessive liquid carryover occurs in the T-junction, leading to complete platform trip and halt production. This is because the downstream process train is not designed to handle excessive liquid. The objective of this research is to quantify the effect of different diameter ratio on phase separation efficiency in T-junction. The liquid carryover is modelled as two-phase air-water flow using Eulerian Mixture Model coupled with Volume of Fluid Method to mimic the slug flow in the main pipe. The focus in this paper is 0.0254 m (1 inch) diameter horizontal main arm and vertical branch arm with diameter ratio of 1.0, 0.5 and 0.3. The present research narrowed the investigation to only slug flow regime using Baker’s map as reference. The investigation found that, contrary to common believe, smaller diameter ratio T-junction perform worse than larger diameter ratio T-junction.

  5. Susceptibility of the eggs of the field slug Deroceras reticulatum to contact with pesticides and substances of biological origin on artificial soil

    NARCIS (Netherlands)

    Iglesias, J.; Castillejo, J.; Ester, A.; Castro, R.; Lombardia, M.J.

    2002-01-01

    The toxicity of 14 substances, including a number of pesticides, to the eggs of the pest slug Deroceras reticulatum was determined in laboratory experiments. Eggs were kept in contact with a precisely defined artificial soil to which a range of concentrations of the test substances had been applied.

  6. Depletion of Serotonin Selectively Impairs Short-Term Memory without Affecting Long-Term Memory in Odor Learning in the Terrestrial Slug "Limax Valentianus"

    Science.gov (United States)

    Santa, Tomofumi; Kirino, Yutaka; Watanabe, Satoshi; Shirahata, Takaaki; Tsunoda, Makoto

    2006-01-01

    The terrestrial slug "Limax" is able to acquire short-term and long-term memories during aversive odor-taste associative learning. We investigated the effect of the selective serotonergic neurotoxin 5,7-dihydroxytryptamine (5,7-DHT) on memory. Behavioral studies indicated that 5,7-DHT impaired short-term memory but not long-term memory. HPLC…

  7. Effect of Gas- and Liquid-injection Methods on Formation of Bubble and Liquid Slug at Merging Micro T-junction

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jun Kyoung [Kyungnam Univ., Changwon (Korea, Republic of); Lee, Chi Young [Pukyong Nat’l Univ., Busan (Korea, Republic of)

    2016-04-15

    In the present experimental study, the effect of gas- and liquid-injected methods on the formation of bubble and liquid slug at the merging micro T-junction of a square microchannel with dimensions 600 μm × 600 μm was investigated. Nitrogen and water were used as test fluids. The superficial velocities of the liquid and gas were in the range of 0.05 - 1 m/s, and 0.1 - 1 m/s, respectively, where the Taylor flow was observed. The bubble length, liquid slug length, bubble velocity, and bubble generation frequency were measured by analyzing the images captured using a high-speed camera. Under similar inlet superficial velocity conditions, in the case of gas injection to the main channel at the merging T-junction (T{sub g}as-liquid), the lengths of the bubble and liquid slug were longer, and the bubble generation frequency was lower than in the case of liquid injection to the main channel at the merging T-junction (T{sub l}iquid-gas). On the other hand, in both cases, the bubble velocity was almost the same. The previous correlation proposed using experimental data for T{sub l}iquid-gas had predicted the present experimental data of bubble length, bubble velocity, liquid slug length, and bubble generation frequency for T{sub g}as-liquid to be ~24%, ~9%, ~39%, ~55%, respectively.

  8. Numerical Study on Bubble Dynamics and Two-Phase Frictional Pressure Drop of Slug Flow Regime in Adiabatic T-junction Square Microchannel

    Directory of Open Access Journals (Sweden)

    K. Kishor

    2017-10-01

    Full Text Available In this study, bubble dynamics and frictional pressure drop associated with gas liquid two-phase slug flow regime in adiabatic T-junction square microchannel has been investigated using CFD. A comprehensive study on the mechanism of bubble formation via squeezing and shearing regime is performed. The randomness and recirculation profiles observed in the squeezing regime are significantly higher as compared to the shearing regime during formation of the slug. Further, effects of increasing gas velocity on bubble length are obtained at fixed liquid velocities and simulated data displayed good agreement with available correlations in literature. The frictional pressure drop for slug flow regime from simulations are also obtained and evaluated against existing separated flow models. A regression correlation has also been developed by modifying C-parameter using separated flow model, which improves the prediction of two-phase frictional pressure drop data within slug flow region, with mean absolute error of 10 %. The influences of fluid properties such as liquid viscosity and surface tension on the two-phase frictional pressure drop are also investigated and compared with developed correlation. The higher liquid viscosity and lower surface tension value resulted in bubble formation via shearing regime.

  9. Sea Dragon

    National Research Council Canada - National Science Library

    1997-01-01

    .... In preparation for these changes, the Navy is exploring new command and control relationships, and the Marine Corps established Sea Dragon to experiment with emerging technologies, operational...

  10. Cross-well slug testing in unconfined aquifers: A case study from the Sleepers River Watershed, Vermont

    Science.gov (United States)

    Belitz, K.; Dripps, W.

    1999-01-01

    Normally, slug test measurements are limited to the well in which the water level is perturbed. Consequently, it is often difficult to obtain reliable estimates of hydraulic properties, particularly if the aquifer is anisotropic or if there is a wellbore skin. In this investigation, we use partially penetrating stress and observation wells to evaluate specific storage, radial hydraulic conductivity and anisotropy of the aquifer, and the hydraulic conductivity of the borehole skin. The study site is located in the W9 subbasin of the Sleepers River Research Watershed, Vermont. At the site, ~3 m of saturated till are partially penetrated by a stress well located in the center of the unconfined aquifer and six observation wells located above, below, and at the depth of the stress well at radial distances of 1.2 and 2.4 m. The observation wells were shut in with inflatable packers. The semianalytical solution of Butler (1995) was used to conduct a sensitivity analysis and to interpret slug test results. The sensitivity analysis indicates that the response of the stress well is primarily sensitive to radial hydraulic conductivity, less sensitive to anisotropy and the conductivity of the borehole skin, and nearly insensitive to specific storage. In contrast, the responses of the observation wells are sensitive to all four parameters. Interpretation of the field data was facilitated by generating type curves in a manner analogous to the method of Cooper et al. (1967). Because the value of radial hydraulic conductivity is obtained from a match point, the number of unknowns is reduced to three. The estimated values of radial hydraulic conductivity and specific storage are comparable to those derived from the methods of Bouwer and Rice (1976) and Cooper et al. (1967). The values and skin conductivity, however, could not have been obtained without the use of observation wells.Normally, slug test measurements are limited to the well in which the water level is perturbed

  11. Regulation of Membrane-Type 4 Matrix Metalloproteinase by SLUG Contributes to Hypoxia-Mediated Metastasis12

    Science.gov (United States)

    Huang, Chi-Hung; Yang, Wen-Hao; Chang, Shyue-Yih; Tai, Shyh-Kuan; Tzeng, Cheng-Hwei; Kao, Jung-Yie; Wu, Kou-Juey; Yang, Muh-Hwa

    2009-01-01

    The hypoxic tumor environment has been shown to be critical to cancer metastasis through the promotion of angiogenesis, induction of epithelial-mesenchymal transition (EMT), and acquisition of invasive potential. However, the impact of hypoxia on the expression profile of the proteolytic enzymes involved in invasiveness is relatively unknown. Membrane-type 4 matrix metalloproteinase (MT4-MMP) is a glycosyl-phosphatidyl inositol-anchored protease that has been shown to be overexpressed in human cancers. However, detailed mechanisms regarding the regulation and function of MT4-MMP expression in tumor cells remain unknown. Here, we demonstrate that hypoxia or overexpression of hypoxia-inducible factor-1α (HIF-1α) induced MT4-MMP expression in human cancer cells. Activation of SLUG, a transcriptional factor regulating the EMT process of human cancers, by HIF-1α was critical for the induction of MT4-MMP under hypoxia. SLUG regulated the transcription of MT4-MMP through direct binding to the E-box located in its proximal promoter. Short-interference RNA-mediated knockdown of MT4-MMP attenuated in vitro invasiveness and in vivo pulmonary colonization of tumor cells without affecting cell migratory ability. MT4-MMP promoted invasiveness and pulmonary colonization through modulation of the expression profile of MMPs and angiogenic factors. Finally, coexpression of HIF-1α and MT4-MMP in human head and neck cancer was predictive of a worse clinical outcome. These findings establish a novel signaling pathway for hypoxia-mediated metastasis and elucidate the underlying regulatory mechanism and functional significance of MT4-MMP in cancer metastasis. PMID:20019845

  12. The displacement of oil polymer slug considering of adsorption effects; Deslocamento de oleo por banco de polimero considerando os efeitos de adsorcao

    Energy Technology Data Exchange (ETDEWEB)

    Ribeiro, Priscila M. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil); Pires, Adolfo P. [Universidade Estadual do Norte Fluminense (UENF), Campos dos Goytacazes, RJ (Brazil)

    2008-07-01

    Among different Enhanced Oil Recovery methods, the injection of chemical solutions plays an important role in mature fields additional recovery. The continuous injection of this kind of fluid would be very expensive, so, the injection of chemical slugs is an attractive alternative to improve the recovery of mature oil fields. Analytical models for 1-D displacement of oil by water with chemical compounds have been developed since the 1960's. This paper presents the 1-D analytical solution of the injection of a chemical slug followed by water drive into an oil reservoir. A flow potential associated with the conservation of water phase is introduced and used as a new independent variable instead of time. This technique permits splitting the system of equations into a thermodynamic system and one transport equation. Another important application of these solutions is the prediction of chemical flooding regardless of the transport properties (relative permeabilities and viscosities). (author)

  13. Emulation and Control of Slugging Flows in a Gas-Lifted Offshore Oil Production Well Through a Lab-sized Facility

    DEFF Research Database (Denmark)

    Jepsen, Kasper Lund; Hansen, Leif; Mai, Christian

    2013-01-01

    flow and pressures in the production well system, which is referred to as the slugging flow problem. This instability is mainly due to the casing-heading mechanism. This work investigates the possibility to use a feedback control for stabilizing the production operation without sacrificing...... the production capability. A labsized production well system is constructed in an economic manner. Afterwards, a simple nonlinear model is derived according to physical principles and then verified with the experimental facility. A observer-based state feedback control is designed to handle the potential...... slugging problem. The developed controller manipulates the openness degree of the production choke based on feedback a number of pressure measurements. The current simulation results showed satisfactory control performances by stabilizing the system operation at some relatively large production rate which...

  14. Sea Legs

    Science.gov (United States)

    Macdonald, Kenneth C.

    Forty-foot, storm-swept seas, Spitzbergen polar bears roaming vast expanses of Arctic ice, furtive exchanges of forbidden manuscripts in Cold War Moscow, the New York city fashion scene, diving in mini-subs to the sea floor hot srings, life with the astronauts, romance and heartbreak, and invading the last bastions of male exclusivity: all are present in this fast-moving, non-fiction account of one woman' fascinating adventures in the world of marine geology and oceanography.

  15. Chemical compounds related to the predation risk posed by malacophagous ground beetles alter self-maintenance behavior of naive slugs (Deroceras reticulatum.

    Directory of Open Access Journals (Sweden)

    Piotr Bursztyka

    Full Text Available Evidence that terrestrial gastropods are able to detect chemical cues from their predators is obvious yet scarce, despite the scientific relevance of the topic to enhancing our knowledge in this area. This study examines the influence of cuticular extracts from predacious ground beetles (Carabus auratus, Carabus hispanus, Carabus nemoralis and Carabus coriaceus, and a neutral insect species (Musca domestica on the shelter-seeking behavior of naive slugs (Deroceras reticulatum. Slugs, known to have a negative phototactic response, were exposed to light, prompting them to make a choice between either a shelter treated with a cuticular extract or a control shelter treated with pure ethyl alcohol. Their behavioral responses were recorded for one hour in order to determine their first shelter choice, their final position, and to compare the percentage of time spent in the control shelters with the time spent in the treated shelters.The test proved to be very effective: slugs spent most of the experiment in a shelter. They spent significantly more time in the control shelter than in the shelter treated with either C. nemoralis (Z = 2.43; p = 0.0151; Wilcoxon matched-pairs signed-ranks test or C. coriaceus cuticular extracts (Z = 3.31; p<0.01; Wilcoxon matched-pairs signed-ranks test, with a seemingly stronger avoidance effect when presented with C. coriaceus extracts. The other cuticular extracts had no significant effect on any of the behavioral items measured. Although it cannot be entirely excluded that the differences observed, are partly due to the intrinsic properties of the vehicle employed to build the cuticular extracts, the results suggest that slugs can innately discriminate amongst different potential predators and adjust their behavioral response according to the relevance of the threat conveyed by their predator's chemical cues.

  16. Chemical compounds related to the predation risk posed by malacophagous ground beetles alter self-maintenance behavior of naive slugs (Deroceras reticulatum).

    Science.gov (United States)

    Bursztyka, Piotr; Saffray, Dominique; Lafont-Lecuelle, Céline; Brin, Antoine; Pageat, Patrick

    2013-01-01

    Evidence that terrestrial gastropods are able to detect chemical cues from their predators is obvious yet scarce, despite the scientific relevance of the topic to enhancing our knowledge in this area. This study examines the influence of cuticular extracts from predacious ground beetles (Carabus auratus, Carabus hispanus, Carabus nemoralis and Carabus coriaceus), and a neutral insect species (Musca domestica) on the shelter-seeking behavior of naive slugs (Deroceras reticulatum). Slugs, known to have a negative phototactic response, were exposed to light, prompting them to make a choice between either a shelter treated with a cuticular extract or a control shelter treated with pure ethyl alcohol. Their behavioral responses were recorded for one hour in order to determine their first shelter choice, their final position, and to compare the percentage of time spent in the control shelters with the time spent in the treated shelters.The test proved to be very effective: slugs spent most of the experiment in a shelter. They spent significantly more time in the control shelter than in the shelter treated with either C. nemoralis (Z = 2.43; p = 0.0151; Wilcoxon matched-pairs signed-ranks test) or C. coriaceus cuticular extracts (Z = 3.31; p<0.01; Wilcoxon matched-pairs signed-ranks test), with a seemingly stronger avoidance effect when presented with C. coriaceus extracts. The other cuticular extracts had no significant effect on any of the behavioral items measured. Although it cannot be entirely excluded that the differences observed, are partly due to the intrinsic properties of the vehicle employed to build the cuticular extracts, the results suggest that slugs can innately discriminate amongst different potential predators and adjust their behavioral response according to the relevance of the threat conveyed by their predator's chemical cues.

  17. Normal endometrial stromal cells regulate 17β-estradiol-induced epithelial-mesenchymal transition via slug and E-cadherin in endometrial adenocarcinoma cells in vitro.

    Science.gov (United States)

    Zhang, Hui; Li, Hongyan; Qi, Shasha; Liu, Zhao; Fu, Yibing; Li, Mingjiang; Zhao, Xingbo

    2017-01-01

    Stroma-tumor communication participates in the pathogenesis of endometrial carcinomas. In previous studies, we found that normal stromal cells inhibited the growth of endometrial carcinoma cells. Here, we investigated the role of normal stromal cells in the epithelial-mesenchymal transition (EMT) of endometrial carcinoma cells and explored the possible mechanism implied. We found that conditioned medium (CM) by normal endometrial stromal cells (NSC) reduced cell growth and induced cell apoptosis in Ishikawa cells. CM by NSC inhibited 17β-estradiol-induced cell growth and apoptosis decrease in Ishikawa cells. Moreover, CM by NSC inhibited the migration and invasion, and 17β-estradiol-induced migration and invasion in Ishikawa cells. Meanwhile, CM by NSC decreased Slug expression and 17β-estradiol-induced Slug expression, increased E-cadherin expression and abolished 17β-estradiol-induced E-cadherin reduction in Ishikawa cells. In conclusion, normal stromal factors can inhibit 17β-estradiol-induced cell proliferation and apoptosis inhibition, and abolished 17β-estradiol-induced EMT in endometrial cancer cell via regulating E-cadherin and Slug expression.

  18. On the interaction of Taylor bubbles rising in two-phase co-current slug flow in vertical columns: turbulent wakes

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, A.M.F.R.; Campos, J.B.L. [Centro de Estudos de Fenomenos de Transporte, Universidade do Porto Rua (Portugal); Coelho Pinheiro, M.N. [Dept. de Engenharia Quimica, Politecnico de Coimbra (Portugal)

    2001-12-01

    An experimental study on the interaction between Taylor bubbles rising through a co-current flowing liquid in a vertical tube with 32 mm of internal diameter is reported. The flow pattern in the bubble's wake was turbulent and the flow regime in the liquid slug was either turbulent or laminar. When the flow regime in the liquid slug is turbulent (i) the minimum distance between bubbles above which there is no interaction is 5D-6D; (ii) the bubble's rising velocity is in excellent agreement with the Nicklin relation; (iii) the experimental values of the bubble length compare well with theoretical predictions (Barnea 1990); (iv) the distance between consecutive bubbles varied from 13D to 16D and is insensitive to the liquid Reynolds number. When the flow regime in the liquid slug is laminar (i) the wake length is about 5D-6D; (ii) the minimum distance between bubbles above which there is no interaction is higher than 25D; (iii) the bubble's rising velocity is significantly smaller than theoretical predictions. These results were explained in the light of the findings of Pinto et al. (1998) on coalescence of two Taylor bubbles rising through a co-current liquid. (orig.)

  19. Fuel slugs considered for use in the high flux reactor EL3; Elements combustibles envisages pour la pile a haut flux EL 3

    Energy Technology Data Exchange (ETDEWEB)

    Stohr, J A; Caillat, R; Gauthron, M; Montagne, R [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    EL3 was designed essentially for the study, under irradiation conditions, of materials used in the construction of atomic reactors. The study schedule allocates considerable time and effort to new types of fuel slugs. The present report described the various types of slug being tested or scheduled for tests. After laboratory study, each slug is tested in an experimental cell in the pile. The best are retained and used to charge the reactor (the present charge is purely provisional to permit first criticality and power rise tests)ren. [French] La pile EL3 est essentiellement destinee a l'etude sous irradiation des materiaux utilises dans la construction des reacteurs atomiques. Dans ce programme, une tres large part est reservee a l'etude de nouveaux elements combustibles. Le present rapport decrit les differentes solutions de cartouches dont l'essai est envisage ou en cours. Apres etude en laboratoire, chacune de ces solutions est testee dans une cellule experimentale en pile. Les meilleures seront retenues pour constituer le chargement normal de la pile (le chargement actuel etant essentiellement une solution provisoire qui a permis la divergence de la pile et les premiers essais de montee en puissance). (auteur)

  20. Using the Slug Mucosal Irritation Assay to Investigate the Tolerability of Tablet Excipients on Human Skin in the Context of the Use of a Nipple Shield Delivery System.

    Science.gov (United States)

    Kendall, Richard; Lenoir, Joke; Gerrard, Stephen; Scheuerle, Rebekah L; Slater, Nigel K H; Tuleu, Catherine

    2017-04-01

    Neonates are particularly challenging to treat. A novel patented drug delivery device containing a rapidly disintegrating tablet held within a modified nipple shield (NSDS) was designed to deliver medication to infants during breastfeeding. However concerns exist around dermatological nipple tolerability with no pharmaceutical safety assessment guidance to study local tissue tolerance of the nipple and the areola. This is the first Slug Mucosal Irritation (SMI) study to evaluate irritancy potential of GRAS excipients commonly used to manufacture rapidly disintegrating immediate release solid oral dosage form METHODS: Zinc sulphate selected as the antidiarrheal model drug that reduces infant mortality, was blended with functional excipients at traditional levels [microcrystalline cellulose, sodium starch glycolate, croscarmellose sodium, magnesium stearate]. Slugs were exposed to blends slurried in human breast milk to assess their stinging, itching or burning potential, using objective values such as mucus production to categorize irritation potency RESULTS: Presently an in vivo assay, previously validated for prediction of ocular and nasal irritation, was used as an alternative to vertebrate models to anticipate the potential maternal dermatological tolerability issues to NSDS tablet components. The excipients did not elicit irritancy. However, mild irritancy was observed when zinc sulphate was present in blends. These promising good tolerability results support the continued investigation of these excipients within NSDS rapidly disintegrating tablet formulations. Topical local tolerance effects being almost entirely limited to irritation, the slug assay potentially adds to the existing preformulation toolbox, and may sit in between the in vitro and existing in vivo assays.

  1. Sea level trends in South East Asian Seas (SEAS)

    Science.gov (United States)

    Strassburg, M. W.; Hamlington, B. D.; Leben, R. R.; Manurung, P.; Lumban Gaol, J.; Nababan, B.; Vignudelli, S.; Kim, K.-Y.

    2014-10-01

    Southeast Asian Seas (SEAS) span the largest archipelago in the global ocean and provide a complex oceanic pathway connecting the Pacific and Indian Oceans. The SEAS regional sea level trends are some of the highest observed in the modern satellite altimeter record that now spans almost two decades. Initial comparisons of global sea level reconstructions find that 17 year sea level trends over the past 60 years exhibit good agreement in areas and at times of strong signal to noise associated decadal variability forced by low frequency variations in Pacific trade winds. The SEAS region exhibits sea level trends that vary dramatically over the studied time period. This historical variation suggests that the strong regional sea level trends observed during the modern satellite altimeter record will abate as trade winds fluctuate on decadal and longer time scales. Furthermore, after removing the contribution of the Pacific Decadal Oscillation (PDO) to sea level trends in the past twenty years, the rate of sea level rise is greatly reduced in the SEAS region. As a result of the influence of the PDO, the SEAS regional sea level trends during 2010s and 2020s are likely to be less than the global mean sea level (GMSL) trend if the observed oscillations in wind forcing and sea level persist. Nevertheless, long-term sea level trends in the SEAS will continue to be affected by GMSL rise occurring now and in the future.

  2. Bubbling bed catalytic hydropyrolysis process utilizing larger catalyst particles and smaller biomass particles featuring an anti-slugging reactor

    Science.gov (United States)

    Marker, Terry L; Felix, Larry G; Linck, Martin B; Roberts, Michael J

    2014-09-23

    This invention relates to a process for thermochemically transforming biomass or other oxygenated feedstocks into high quality liquid hydrocarbon fuels. In particular, a catalytic hydropyrolysis reactor, containing a deep bed of fluidized catalyst particles is utilized to accept particles of biomass or other oxygenated feedstocks that are significantly smaller than the particles of catalyst in the fluidized bed. The reactor features an insert or other structure disposed within the reactor vessel that inhibits slugging of the bed and thereby minimizes attrition of the catalyst. Within the bed, the biomass feedstock is converted into a vapor-phase product, containing hydrocarbon molecules and other process vapors, and an entrained solid char product, which is separated from the vapor stream after the vapor stream has been exhausted from the top of the reactor. When the product vapor stream is cooled to ambient temperatures, a significant proportion of the hydrocarbons in the product vapor stream can be recovered as a liquid stream of hydrophobic hydrocarbons, with properties consistent with those of gasoline, kerosene, and diesel fuel. Separate streams of gasoline, kerosene, and diesel fuel may also be obtained, either via selective condensation of each type of fuel, or via later distillation of the combined hydrocarbon liquid.

  3. Bubbling bed catalytic hydropyrolysis process utilizinig larger catalyst particles and small biomass particles featuring an anti-slugging reactor

    Science.gov (United States)

    Marker, Terry L.; Felix, Larry G.; Linck, Martin B.; Roberts, Michael J.

    2016-12-06

    This invention relates to a process for thermochemically transforming biomass or other oxygenated feedstocks into high quality liquid hydrocarbon fuels. In particular, a catalytic hydropyrolysis reactor, containing a deep bed of fluidized catalyst particles is utilized to accept particles of biomass or other oxygenated feedstocks that are significantly smaller than the particles of catalyst in the fluidized bed. The reactor features an insert or other structure disposed within the reactor vessel that inhibits slugging of the bed and thereby minimizes attrition of the catalyst. Within the bed, the biomass feedstock is converted into a vapor-phase product, containing hydrocarbon molecules and other process vapors, and an entrained solid char product, which is separated from the vapor stream after the vapor stream has been exhausted from the top of the reactor. When the product vapor stream is cooled to ambient temperatures, a significant proportion of the hydrocarbons in the product vapor stream can be recovered as a liquid stream of hydrophobic hydrocarbons, with properties consistent with those of gasoline, kerosene, and diesel fuel. Separate streams of gasoline, kerosene, and diesel fuel may also be obtained, either via selective condensation of each type of fuel, or via later distillation of the combined hydrocarbon liquid.

  4. Stratified flow instability and slug formation leading to condensation-induced water hammer in a horizontal refrigerant pipe

    International Nuclear Information System (INIS)

    Samuel Martin, C.

    2005-01-01

    Full text of publication follows: An experimental apparatus was designed for the purpose of investigating the phenomenon of condensation-induced water hammer in an ammonia refrigeration system. Water hammer was initiated by introducing warm ammonia gas over static subcooled ammonia liquid placed in a horizontal 146.3 mm diameter carbon steel pipe 6.0 m in length. By means of fast response piezoelectric pressure transducers and a high speed data acquisition system rapid dynamic pressures were recorded whenever a shock event occurred. Moreover, by means of top-mounted diaphragm pressure transducers the speed of liquid slugs propagating along the pipe was determined. The occurrence of condensation induced water hammer depended upon three major variables; namely, (1) initial liquid depth, (2) liquid temperature, and (3) mass flow rate of warm gas. For given liquid depth and temperature, once the warm gas threshold conditions were exceeded shocks occurred with greater magnitude as the mass flow rate of gas input was increased. With adequate subcooling condensation-induced water hammer occurred for initial liquid depths ranging from 25% to 95% of internal pipe diameter. The threshold mass flow rate of warm gas necessary to initiate water hammer was greater as the initial liquid depth was lowered. Based upon experimental results obtained from four pressure transducers located on the top of the test pipe conditions corresponding to bridging were ascertained. For various initial liquid depths the onset of instability from stratified flow to bridging was correlated with the Taitel-Dukler instability criterion. (author)

  5. Slug-flow dynamics with phase change heat transfer in compact heat exchangers with oblique wavy walls

    Science.gov (United States)

    Morimoto, Kenichi; Kinoshita, Hidenori; Matsushita, Ryo; Suzuki, Yuji

    2017-11-01

    With abundance of low-temperature geothermal energy source, small-scale binary-cycle power generation system has gained renewed attention. Although heat exchangers play a dominant role in thermal efficiency and the system size, the optimum design strategy has not been established due to complex flow phenomena and the lack of versatile heat transfer models. In the present study, the concept of oblique wavy walls, with which high j/f factor is achieved by strong secondary flows in single-phase system, is extended to two-phase exchangers. The present analyses are based on evaporation model coupled to a VOF technique, and a train of isolated bubbles is generated under the controlled inlet quality. R245fa is adopted as a low boiling-point working media, and two types of channels are considered with a hydraulic diameter of 4 mm: (i) a straight circular pipe and (ii) a duct with oblique wavy walls. The focus is on slug-flow dynamics with evaporation under small capillary but moderate Weber numbers, where the inertial effect as well as the surface tension is of significance. A possible direction of the change in thermo-physical properties is explored by assuming varied thermal conductivity. Effects of the vortical motions on evaporative heat transfer are highlighted. This work has been supported by the New Energy and Industrial Technology Development Organization (NEDO), Japan.

  6. Low-level overexpression of p53 promotes warfarin-induced calcification of porcine aortic valve interstitial cells by activating Slug gene transcription.

    Science.gov (United States)

    Gao, Li; Ji, Yue; Lu, Yan; Qiu, Ming; Shen, Yejiao; Wang, Yaqing; Kong, Xiangqing; Shao, Yongfeng; Sheng, Yanhui; Sun, Wei

    2018-03-09

    The most frequently used oral anti-coagulant warfarin has been implicated in inducing calcification of aortic valve interstitial cells (AVICs), whereas the mechanism is not fully understood. The low-level activation of p53 is found to be involved in osteogenic transdifferentiation and calcification of AVICs. Whether p53 participates in warfarin-induced AVIC calcification remains unknown. In this study, we investigated the role of low-level p53 overexpression in warfarin-induced porcine AVIC (pAVIC) calcification. Immunostaining, quantitative PCR, and Western blotting revealed that p53 was expressed in human and pAVICs and that p53 expression was slightly increased in calcific human aortic valves compared with non-calcific valves. Terminal deoxynucleotidyltransferase-mediated dUTP nick end labeling staining indicated that apoptosis slightly increased in calcific aortic valves than in non-calcific valves. Warfarin treatment led to a low-level increase of p53 mRNA and protein in both pAVICs and mouse aortic valves. Low-level overexpression of p53 in pAVICs via an adenovirus vector did not affect pAVIC apoptosis but promoted warfarin-induced calcium deposition and expression of osteogenic markers. shRNA-mediated p53 knockdown attenuated the pAVIC calcium deposition and osteogenic marker expression. Moreover, ChIP and luciferase assays showed that p53 was recruited to the slug promoter and activated slug expression in calcific pAVICs. Of note, overexpression of Slug increased osteogenic marker Runx2 expression, but not pAVIC calcium deposition, and Slug knockdown attenuated pAVIC calcification and p53-mediated pAVIC calcium deposition and expression of osteogenic markers. In conclusion, we found that p53 plays an important role in warfarin induced pAVIC calcification, and increased slug transcription by p53 is required for p53-mediated pAVIC calcification. © 2018 by The American Society for Biochemistry and Molecular Biology, Inc.

  7. Real-time measurement of gas and liquid flow rates in two-phase slug flow by an advanced electromagnetic flowmeter and conductance probes

    International Nuclear Information System (INIS)

    Kim Jongrok; Ahn Yeh-Chan; Oh Byung Do; Kang Deok-Hong; Kim Moo Hwan

    2005-01-01

    Full text of publication follows: In order to measure the liquid mean velocity (cross-sectional average) in two-phase flow with an electromagnetic flowmeter, each flow pattern must be considered separately because of their different flow characteristics. Since bubbly flow can be approximated as a homogeneous mixture of gas and liquid at the same velocity, there are no additional measurement difficulties compared to single-phase flow. Cha et al. (2002) and Knoll (1991) reported that this approximation gives rise to no more than a 5% error in the liquid flow rate when the void fraction is less than 0.25. Annular flow measurements are also similar to those of single-phase flow if the film is assumed to be uniform and smooth, and the gas core is located at the center of the flow tube. Slug flow, however, is the most complicated, since the liquid axial velocity over a slug unit experiences considerable acceleration or deceleration. Therefore an electromagnetic flowmeter with high temporal resolution is needed. In slug flow, film velocity measurements are also difficult to perform because the liquid film is very thin and can be easily disturbed, thus altering the flow field. Only two experimental results for liquid film velocity measurement could be found. They were performed using photo-chromic dye method (DeJesus, 1997) and PIV technique (Polonsky et al., 1999). In this study, an advanced electromagnetic flow-metry was developed to measure liquid mean velocity with high transients. In addition, two ring-type conductance meters were manufactured to measure void fraction and its propagation speed in slug flow. The signal of conductance meter with two rings depends on liquid temperature. Therefore a conductance meter with three rings designed by Coney (1973), which is independent of liquid temperature, was used and experimentally proved. The manufactured conductance meters showed a good repeatability and agreement with the analytical solution by Coney (1973). From the

  8. Sea Ice

    Science.gov (United States)

    Perovich, D.; Gerland, S.; Hendricks, S.; Meier, Walter N.; Nicolaus, M.; Richter-Menge, J.; Tschudi, M.

    2013-01-01

    During 2013, Arctic sea ice extent remained well below normal, but the September 2013 minimum extent was substantially higher than the record-breaking minimum in 2012. Nonetheless, the minimum was still much lower than normal and the long-term trend Arctic September extent is -13.7 per decade relative to the 1981-2010 average. The less extreme conditions this year compared to 2012 were due to cooler temperatures and wind patterns that favored retention of ice through the summer. Sea ice thickness and volume remained near record-low levels, though indications are of slightly thicker ice compared to the record low of 2012.

  9. Sea level change

    Digital Repository Service at National Institute of Oceanography (India)

    Church, J.A.; Clark, P.U.; Cazenave, A.; Gregory, J.M.; Jevrejeva, S.; Levermann, A.; Merrifield, M.A.; Milne, G.A.; Nerem, R.S.; Nunn, P.D.; Payne, A.J.; Pfeffer, W.T.; Stammer, D.; Unnikrishnan, A.S.

    This chapter considers changes in global mean sea level, regional sea level, sea level extremes, and waves. Confidence in projections of global mean sea level rise has increased since the Fourth Assessment Report (AR4) because of the improved...

  10. Sea level trends in Southeast Asian seas

    Science.gov (United States)

    Strassburg, M. W.; Hamlington, B. D.; Leben, R. R.; Manurung, P.; Lumban Gaol, J.; Nababan, B.; Vignudelli, S.; Kim, K.-Y.

    2015-05-01

    Southeast Asian seas span the largest archipelago in the global ocean and provide a complex oceanic pathway connecting the Pacific and Indian oceans. The Southeast Asian sea regional sea level trends are some of the highest observed in the modern satellite altimeter record that now spans almost 2 decades. Initial comparisons of global sea level reconstructions find that 17-year sea level trends over the past 60 years exhibit good agreement with decadal variability associated with the Pacific Decadal Oscillation and related fluctuations of trade winds in the region. The Southeast Asian sea region exhibits sea level trends that vary dramatically over the studied time period. This historical variation suggests that the strong regional sea level trends observed during the modern satellite altimeter record will abate as trade winds fluctuate on decadal and longer timescales. Furthermore, after removing the contribution of the Pacific Decadal Oscillation (PDO) to sea level trends in the past 20 years, the rate of sea level rise is greatly reduced in the Southeast Asian sea region. As a result of the influence of the PDO, the Southeast Asian sea regional sea level trends during the 2010s and 2020s are likely to be less than the global mean sea level (GMSL) trend if the observed oscillations in wind forcing and sea level persist. Nevertheless, long-term sea level trends in the Southeast Asian seas will continue to be affected by GMSL rise occurring now and in the future.

  11. Changes in cell-type composition in digestive gland of slugs and its influence in biomarkers following transplantation between a relatively unpolluted and a chronically metal-polluted site

    International Nuclear Information System (INIS)

    Zaldibar, B.; Cancio, I.; Soto, M.; Marigomez, I.

    2008-01-01

    Changes in cell-type composition (CCTC) is a general phenomenon that takes place in the digestive gland epithelium of stressed molluscs. The aim of the present work was to determine whether CCTC is a reversible process in the digestive gland of sentinel slugs chronically exposed to metal pollution and how CCTC affects metal accumulation parameters and different cell and tissue biomarkers of exposure and effect. Slugs (Arion ater) from an abandoned zinc mine were transferred to a relatively unpolluted site and the other way around for 3, 10 and 28 d. The volume density of black silver deposits (Vv BSD ) after autometallography, and metallothionein (MT) levels were used as biomarkers of exposure to metals and CCTC and lysosomal responses were selected as effect biomarkers. Results indicated that slugs were sensitive to recent metal pollution; however, slugs chronically exposed to metals presented some characteristic features and were less responsive to pollution cessation without signs of CCTC reversal. - Cell and tissue-level biomarkers in slugs after recent and chronic metal pollution

  12. Analyses and estimates of hydraulic conductivity from slug tests in alluvial aquifer underlying Air Force Plant 4 and Naval Air Station-Joint Reserve Base Carswell Field, Fort Worth, Texas

    Science.gov (United States)

    Houston, Natalie A.; Braun, Christopher L.

    2004-01-01

    This report describes the collection, analyses, and distribution of hydraulic-conductivity data obtained from slug tests completed in the alluvial aquifer underlying Air Force Plant 4 and Naval Air Station-Joint Reserve Base Carswell Field, Fort Worth, Texas, during October 2002 and August 2003 and summarizes previously available hydraulic-conductivity data. The U.S. Geological Survey, in cooperation with the U.S. Air Force, completed 30 slug tests in October 2002 and August 2003 to obtain estimates of horizontal hydraulic conductivity to use as initial values in a ground-water-flow model for the site. The tests were done by placing a polyvinyl-chloride slug of known volume beneath the water level in selected wells, removing the slug, and measuring the resulting water-level recovery over time. The water levels were measured with a pressure transducer and recorded with a data logger. Hydraulic-conductivity values were estimated from an analytical relation between the instantaneous displacement of water in a well bore and the resulting rate of head change. Although nearly two-thirds of the tested wells recovered 90 percent of their slug-induced head change in less than 2 minutes, 90-percent recovery times ranged from 3 seconds to 35 minutes. The estimates of hydraulic conductivity range from 0.2 to 200 feet per day. Eighty-three percent of the estimates are between 1 and 100 feet per day.

  13. Flow visualization study of post critical heat flux region for inverted bubbly, slug and annular flow regimes

    International Nuclear Information System (INIS)

    Denten, J.G.; Ishii, M.

    1988-11-01

    A visual study of film boiling using still photographic and high- speed motion picture methods was carried out in order to analyze the post-CHF hydrodynamics for steady-state inlet pre-CHF two-phase flow regimes. Pre-CHF two-phase flow regimes were established by introducing Freon 113 liquid and nitrogen gas into a jet core injection nozzle. An idealized, post-CHF two-phase core initial flow geometry (cylindrical multiphase jet core surrounded by a coaxial annulus of gas) was established at the nozzle exit by introducing nitrogen gas into the annular gap between the jet nozzle two-phase effluent and the heated test section inlet. For the present study three basic post-CHF flow regimes have been observed: the rough wavy regime (inverted annular flow preliminary break down), the agitated regime (transition between inverted annular and dispersed droplet flow), and the dispersed ligament/droplet regime. For pre-CHF bubbly flow in the jet nozzle, the post-CHF flow (beginning from jet nozzle exit/heated test section inlet) consists of the rough wavy regime, followed by the agitated and then the dispersed ligament/droplet regime. In the same way, for pre-CHF slug flow in the jet core, the post-CHF flow is comprised of the agitated regime at the nozzle exit, followed by the dispersed regime. Pre-CHF annular jet core flow results in a small, depleted post-CHF agitated flow regime at the nozzle exit, immediately followed by the dispersed ligament/droplet regime. Observed post dryout hydrodynamic behavior is reported, with particular attention given to the transition flow pattern between inverted annular and dispersed droplet flow. 43 refs., 20 figs., 5 tabs

  14. Two-phase flow characteristic of inverted bubbly, slug and annular flow in post-critical heat flux region

    International Nuclear Information System (INIS)

    Ishii, M.; Denten, J.P.

    1988-01-01

    Inverted annular flow can be visualized as a liquid jet-like core surrounded by a vapor annulus. While many analytical and experimental studies of heat transfer in this regime have been performed, there is very little understanding of the basic hydrodynamics of the post-CHF flow field. However, a recent experimental study was done that was able to successfully investigate the effects of various steady-state inlet flow parameters on the post-CHF hydrodynamics of the film boiling of a single phase liquid jet. This study was carried out by means of a visual photographic analysis of an idealized single phase core inverted annular flow initial geometry (single phase liquid jet core surrounded by a coaxial annulus of gas). In order to extend this study, a subsequent flow visualization of an idealized two-phase core inverted annular flow geometry (two-phase central jet core, surrounded by a coaxial annulus of gas) was carried out. The objective of this second experimental study was to investigate the effect of steady-state inlet, pre-CHF two-phase jet core parameters on the hydrodynamics of the post-CHF flow field. In actual film boiling situations, two-phase flows with net positive qualities at the CHF point are encountered. Thus, the focus of the present experimental study was on the inverted bubbly, slug, and annular flow fields in the post dryout film boiling region. Observed post dryout hydrodynamic behavior is reported. A correlation for the axial extent of the transition flow pattern between inverted annular and dispersed droplet flow (the agitated regime) is developed. It is shown to depend strongly on inlet jet core parameters and jet void fraction at the dryout point. 45 refs., 9 figs., 4 tabs

  15. Two-phase flow characteristic of inverted bubbly, slug, and annular flow in post-critical heat flux region

    International Nuclear Information System (INIS)

    Ishii, M.; Denten, J.P.

    1989-01-01

    Inverted annular flow can be visualized as a liquid jet-like core surrounded by a vapor annulus. While many analytical and experimental studies of heat transfer in this regime have been performed, there is very little understanding of the basic hydrodynamics of the post-critical heat flux (CHF) flow field. However, a recent experimental study was done that was able to successfully investigate the effects of various steady-state inlet flow parameters on the post-CHF hydrodynamics of the film boiling of a single phase liquid jet. This study was carried out by means of a visual photographic analysis of an idealized single phase core inverted annular flow initial geometry (single phase liquid jet core surrounded by a coaxial annulus of gas). In order to extend this study, a subsequent flow visualization of an idealized two-phase core inverted annular flow geometry (two-phase central jet core, surrounded by a coaxial annulus of gas) was carried out. The objective of this second experimental study was to investigate the effect of steady-state inlet, pre-CHF two-phase jet core parameters on the hydrodynamics of the post-CHF flow field. In actual film boiling situations, two-phase flows with net positive qualities at the CHF point are encountered. Thus, the focus of the present experimental study was on the inverted bubbly, slug, and annular flow fields in the post dryout film boiling region. Observed post dryout hydrodynamic behavior is reported. A correlation for the axial extent of the transition flow pattern between inverted annular and dispersed droplet flow (the agitated regime) is developed. It is shown to depend strongly on inlet jet core parameters and jet void fraction at the dryout point

  16. Production polyphasique. Modélisation des écoulements à bouchons Multiphase Production Slug-Flow Modeling

    Directory of Open Access Journals (Sweden)

    Drouffe J. M.

    2006-11-01

    Full Text Available L'exploitation des hydrocarbures en mer reste une activité coûteuse et qui peut, même, se révéler, éventuellement dangereuse. Les concepts de production polyphasique tels que Poséidon permettent à la fois : - une réduction importante des coûts de production; - la suppression des risques humains liés à la présence permanente en mer d'équipes importantes. Les programmes de simulation des écoulements diphasiques actuellement disponibles pour la mise en oeuvre de ces concepts, sont tous basés sur une approche déterministeclassique. Cet article présente une nouvelle approche statistiquenon conventionnelle qui devrait nous permettre de mieux préciser les caractéristiques des écoulements à bouchons et donc de pouvoir mieux dimensionner et exploiter nos futures installations de production et transport polyphasique longue distance. Offshore hydrocarbon production remains a costly venture, and even one that might possibly be dangerous. Multiphase production concepts such as Poseidon make for both a considerable reduction in production costs and the elimination of human risks linked to the constant offshore presence of large crews. The two-phase flow simulation programs now available for implementing such concepts are all based on a standard deterministicapproach. This article describes a new and unconventional statisticalapproach that we feel more accurately describes the characteristics of slug flows and hence is more effecting for the sizing and operating of future production and long-distance pipelining installations.

  17. Sea salt

    OpenAIRE

    Galvis-Sánchez, Andrea C.; Lopes, João Almeida; Delgadillo, Ivone; Rangel, António O. S. S.

    2013-01-01

    The geographical indication (GI) status links a product with the territory and with the biodiversity involved. Besides, the specific knowledge and cultural practices of a human group that permit transforming a resource into a useful good is protected under a GI designation. Traditional sea salt is a hand-harvested product originating exclusively from salt marshes from specific geographical regions. Once salt is harvested, no washing, artificial drying or addition of anti-caking agents are all...

  18. TGF-beta1-induced EMT of non-transformed prostate hyperplasia cells is characterized by early induction of SNA12/slug

    Czech Academy of Sciences Publication Activity Database

    Slabáková, Eva; Pernicová, Zuzana; Slavíčková, Eva; Staršíchová, Andrea; Kozubík, Alois; Souček, Karel

    2011-01-01

    Roč. 71, č. 12 (2011), s. 1332-1343 ISSN 0270-4137 R&D Projects: GA ČR(CZ) GA310/07/0961; GA ČR(CZ) GD303/09/H048; GA MZd NS9600; GA MZd NS9956 Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702 Keywords : epithelial-mesenchymal transition * SNAI2/Slug * transforming growth factor-beta1 Subject RIV: BO - Biophysics Impact factor: 3.485, year: 2011

  19. Microstructure and electrical properties of slug-type resistors based on B4C and TiC - ESCA - XPS and impedance spectroscopy investigations

    International Nuclear Information System (INIS)

    Klimiec, E.; Zaraska, W.; Stobiecki, T.; Bak, W.; Starzyk, F.

    2000-01-01

    The microstructure and electrical properties of slug-type resistors based on B 4 C and TiC were investigated. From XPS measurements was deducted that Ti in TiO 2 is in intermediate oxidation number between Ti +4 and Ti +3 . The impedance of both type of resistors is independent on frequency in the range from 10 3 to 10 4 Hz, only very subtle differences above 10 4 Hz are observed. The metallic type conductivity in TiC and semiconducting in B 4 C was established. (author)

  20. Numerical and experimental study of the slug-flow regime in a mixture of castor and paraffin oils in a T-type microchannel

    Science.gov (United States)

    Minakov, A. V.; Shebeleva, A. A.; Yagodnitsyna, A. A.; Kovalev, A. V.; Bilsky, A. V.

    2017-09-01

    The slow-flug regime in a mixture of castor and paraffin oils in a T-type microchannel with crosssectional dimensions of 200 × 400 μm has been studied by numerical and experimental methods. The domain of existence of the slow-flug regime in this system has been determined. Dependence of the paraffin-oil slug length on the ratio of flow rates of the mixture components is established. Comparison of the calculated and experimental data shows their good agreement.

  1. Measurement and study of amplitudes and velocities of void fraction waves in two-phase gas-liquid flow ranging from bubbly flow to slug flow

    International Nuclear Information System (INIS)

    Tournaire, Agnes

    1987-01-01

    The objective of this research thesis is to study the behaviour of waves at the vicinity of the bubble-slug transition, and to compare it with the one predicted by models. The author also addresses the bubbly regime, and particularly the evolution of wave amplitude whereas studies had been until then limited to the study of wave speed. The first part of the thesis reports the development of a system of vacuum rate measurements in cylindrical duct. The second part proposes the description of the experimental installation, and the third part reports experimental results and discusses them. Finally, the author compares these results with those predicted by using a kinematic modelling [fr

  2. In Search of a Unified Theory of Biological Organization: What Does the Motor System of a Sea Slug Tell Us About Human Motor Integration?

    Science.gov (United States)

    1992-04-07

    integrated activity of large numbers of neurons might arise from interactions occurring localy between indi- vidual neurons. Thanks to the work of Rene ... Descartes and Euclid wouid like us to believe. the possibility of high-dimensiona space. of noniinearities. and of the dialectic be- tween structure

  3. Testing the snake-detection hypothesis: larger early posterior negativity in humans to pictures of snakes than to pictures of other reptiles, spiders and slugs.

    Science.gov (United States)

    Van Strien, Jan W; Franken, Ingmar H A; Huijding, Jorg

    2014-01-01

    According to the snake detection hypothesis (Isbell, 2006), fear specifically of snakes may have pushed evolutionary changes in the primate visual system allowing pre-attentional visual detection of fearful stimuli. A previous study demonstrated that snake pictures, when compared to spiders or bird pictures, draw more early attention as reflected by larger early posterior negativity (EPN). Here we report two studies that further tested the snake detection hypothesis. In Study 1, we tested whether the enlarged EPN is specific for snakes or also generalizes to other reptiles. Twenty-four healthy, non-phobic women watched the random rapid serial presentation of snake, crocodile, and turtle pictures. The EPN was scored as the mean activity at occipital electrodes (PO3, O1, Oz, PO4, O2) in the 225-300 ms time window after picture onset. The EPN was significantly larger for snake pictures than for pictures of the other reptiles. In Study 2, we tested whether disgust plays a role in the modulation of the EPN and whether preferential processing of snakes also can be found in men. 12 men and 12 women watched snake, spider, and slug pictures. Both men and women exhibited the largest EPN amplitudes to snake pictures, intermediate amplitudes to spider pictures and the smallest amplitudes to slug pictures. Disgust ratings were not associated with EPN amplitudes. The results replicate previous findings and suggest that ancestral priorities modulate the early capture of visual attention.

  4. Modeling slug tests in unconfined aquifers with both oscillatory and overdamped responses, and with low-K and high-K skin effects

    Science.gov (United States)

    Thoma, M. J.; Malama, B.; Barrash, W.; Bohling, G.; Butler, J. J.

    2009-12-01

    We extend the models for slug tests developed by Hyder et al. (1994) and Butler and Zhan (2004) to obtain a single general model for slug tests in unconfined aquifers in partially penetrating wells with a near-well disturbed zone (skin). The full range of responses, oscillatory to overdamped, is considered since both types of responses are common in wells in unconsolidated coarse fluvial aquifers, and others. The general semi-analytical solution allows for skin and formation storage as well as anisotropy in skin and formation hydraulic conductivity (K). The water table is treated as a fixed head boundary so the solution is applicable for wells screened below the water table. The model is validated by comparison with other models and by matching field data from unconfined fluvial aquifers at sites in Nebraska (MSEA) and Idaho (BHRS). We examine the effects of varying skin K and skin thickness to simulate the impact of a near-well disturbed zone that is lower (damage) or higher (filter pack) K than the formation. Results indicate that, for a given set of measured behavior at an example test zone, minor progressive decreases in estimated formation K occur with increases in assumed skin K, and moderate increases in estimated formation K occur with decreases in assumed skin K. Major increases (orders of magnitude) in estimated formation K occur with increased thickness of low-K skin. The importance of incorporating a finite-thickness representation of the skin, rather than the conventional infinitely thin representation, is also addressed.

  5. A Unified Model for Slug Flow Generation Modélisation de la formation des bouchons : vers un modèle stochastique unifié

    Directory of Open Access Journals (Sweden)

    Bernicot M.

    2006-11-01

    Full Text Available In order to improve the global safety and reliability level of multi-phase production systems and to guarantee their economical efficiency, we need a better understanding and control of hydraulic instabilities observed at the outlet of multi-phase sea-lines. This may be obtained through the development of slug flow stochastic models, which must be able to explain:(a The generation of the various types of slug length distributions which are observed on experimental data sets. (b The evolution of these distributions along the sea-lines up to their outlets, where large hydraulic fluctuations may be dangerous for the treatment installations. Based on experimental as well as theoretical arguments, we present such a model with emphasis on slug generation. We give a detailed theoretical analysis, together with a discussion of the underlying assumptions which justify the introduction of this model. Ce résumé contient des formules (*** qui ne peuvent s'afficher à l'écran. Pour garantir à la fois la sûreté de fonctionnement et la rentabilité des systèmes de production avec transport polyphasique, il est nécessaire de mieux comprendre et maîtriser les phénomènes d'instabilité hydraulique dans les conduites polyphasiques. Ceci suppose la mise au point et l'utilisation de Modèles de Simulation des écoulements portant, non seulement sur l'évolution dans le temps et en tout point de la conduite des valeurs moyennes des diverses variables (cf. le modèle TACITE, mais aussi sur leurs aspects stochastiques en prenant spécialement en compte : - les lois statistiques propres des divers mécanismes fondamentaux de formation des bouchons (distribution des longueurs de bouchons de liquide et de poches de gaz; - l'évolution de ces lois statistiques dans le temps et tout le long de la conduite (et ceci, jusqu'à son extrémité, extrémité dont les caractéristiques intéressent tout spécialement l'opérateur de la conduite. Nous présenterons ici

  6. Effects of the nematode Phasmarhabditis hermaphrodita and of venom from the endoparasitic wasp Pimpla hypochondriaca on survival and food consumption of the pest slug Deroceras reticulatum; implications for novel biocontrol strategies.

    Science.gov (United States)

    Richards, Elaine H; DeMarzo, Damian; Port, Gordon R; Dani, M Paulina; Walters, Keith F A

    2008-07-01

    Controlling pests through disruption of biochemical pathways by physiologically active compounds/factors from animals and plants represents an expanding field of research. The authors investigated whether such factors in venom from the wasp Pimpla hypochondriaca (Retzius) can affect the viability and food consumption of the slug Deroceras reticulatum (Müller), and whether they can improve the efficacy of nematode-induced slug mortality. Exposure of slugs to 4 mL of water containing 500, 1000 and 5000 Phasmarhabditis hermaphrodita (Schneider) resulted in significant increases in mortality (with hazard ratios of 3.5, 3.9 and 5.8 respectively) and significant reductions in total food consumption and mean food consumption each day for 21 days. Injection of slugs with 4, 8 or 12 microL of P. hypochondriaca venom resulted in significant increases in mortality (with hazard ratios of 3.3, 4.5 and 9.0 respectively) and significant reductions in total food consumption compared with the controls. However, there was no significant effect of venom on the mean food consumption on individual days of the 21 day assay period, although significant reductions occurred for the 8 and 12 microL doses up to day 10. Injecting slugs with 4 microL of venom prior to exposure to 500 nematodes had no synergistic effect on either mortality or food consumption compared with either of the individual treatments. Pimpla hypochondriaca venom contains factors capable of killing and reducing food consumption by D. reticulatum. The utilization of these factors as components of integrated pest management strategies is discussed.

  7. Empirical Correlations and CFD Simulations of Vertical Two-Phase Gas-Liquid (Newtonian and Non-Newtonian) Slug Flow Compared Against Experimental Data of Void Fraction

    DEFF Research Database (Denmark)

    Ratkovich, Nicolas Rios; Majumder, S.K.; Bentzen, Thomas Ruby

    2013-01-01

    Gas-Newtonian liquid two-phase flows (TPFs) are presented in several industrial processes (e.g. oil-gas industry). In spite of the common occurrence of these TPFs, the understanding of them is limited compared to single-phase flows. Various studies on TPF focus on developing empirical correlations...... based on large sets of experimental data for void fraction, which have proven accurate for specific conditions for which they were developed limiting their applicability. On the other hand, few studies focus on gas-non-Newtonian liquids TPFs, which are very common in chemical processes. The main reason...... is due to the characterization of the viscosity, which determines the hydraulic regime and flow behaviours of the system. The focus of this study is the analysis of the TPF (slug flow) for Newtonian and non-Newtonian liquids in a vertical pipe in terms of void fraction using computational fluid dynamics...

  8. Depletion of serotonin selectively impairs short-term memory without affecting long-term memory in odor learning in the terrestrial slug Limax valentianus.

    Science.gov (United States)

    Shirahata, Takaaki; Tsunoda, Makoto; Santa, Tomofumi; Kirino, Yutaka; Watanabe, Satoshi

    2006-01-01

    The terrestrial slug Limax is able to acquire short-term and long-term memories during aversive odor-taste associative learning. We investigated the effect of the selective serotonergic neurotoxin 5,7-dihydroxytryptamine (5,7-DHT) on memory. Behavioral studies indicated that 5,7-DHT impaired short-term memory but not long-term memory. HPLC (high-performance liquid chromatography) analysis revealed that 5,7-DHT significantly reduced serotonin content in the central nervous system. The present study suggests that acquisition, retention, and/or retrieval of short-term memory involves serotonin, and neither acquisition nor retrieval of long-term memory requires serotonin at a level as high as that required for short-term memory.

  9. Three-dimensional one-way bubble tracking method for the prediction of developing bubble-slug flows in a vertical pipe. 1st report, models and demonstration

    International Nuclear Information System (INIS)

    Tamai, Hidesada; Tomiyama, Akio

    2004-01-01

    A three-dimensional one-way bubble tracking method is one of the most promising numerical methods for the prediction of a developing bubble flow in a vertical pipe, provided that several constitutive models are prepared. In this study, a bubble shape, an equation of bubble motion, a liquid velocity profile, a pressure field, turbulent fluctuation and bubble coalescence are modeled based on available knowledge on bubble dynamics. Bubble shapes are classified into four types in terms of bubble equivalent diameter. A wake velocity model is introduced to simulate approaching process among bubbles due to wake entrainment. Bubble coalescence is treated as a stochastic phenomenon with the aid of coalescence probabilities that depend on the sizes of two interacting bubbles. The proposed method can predict time-spatial evolution of flow pattern in a developing bubble-slug flow. (author)

  10. Transverse heat transfer coefficient in the dual channel ITER TF CICCs Part II. Analysis of transient temperature responses observed during a heat slug propagation experiment

    Science.gov (United States)

    Lewandowska, Monika; Herzog, Robert; Malinowski, Leszek

    2015-01-01

    A heat slug propagation experiment in the final design dual channel ITER TF CICC was performed in the SULTAN test facility at EPFL-CRPP in Villigen PSI. We analyzed the data resulting from this experiment to determine the equivalent transverse heat transfer coefficient hBC between the bundle and the central channel of this cable. In the data analysis we used methods based on the analytical solutions of a problem of transient heat transfer in a dual-channel cable, similar to Renard et al. (2006) and Bottura et al. (2006). The observed experimental and other limits related to these methods are identified and possible modifications proposed. One result from our analysis is that the hBC values obtained with different methods differ by up to a factor of 2. We have also observed that the uncertainties of hBC in both methods considered are much larger than those reported earlier.

  11. An Experimental and analytical study on the bubble-to-slug flow regime transition based on the void wave instability

    International Nuclear Information System (INIS)

    Song, Chul Hwa

    1995-02-01

    An experimental and analytical work is performed to investigate the relation between the developing phenomena in bubble flow and the propagation phenomena of void waves. For this purpose, the structural developments in bubble flow and the propagation property of void waves are measured over a broad range of flow conditions including the bubble-to-slug flow regime transition (BSFRT) region. And a linear stability analysis is performed, based on the two-fluid model, to establish the analytical model on the wave propagation parameters, and the predictability of the model is validated by comparing analytical results with experimental observations. In the experimental work, an impedance void meter is developed to measure the void fraction, and a series of test are performed by varying the bubble size in order to investigate the bubble size effect on the bubble flow structures for various flow conditions. Statistical signal processing techniques are applied to void signals in order to objectively identify the changing modes of bubble flow structures and to estimate the wave propagation properties. The impedance void meter developed in this study showed very good temporal and spatial resolutions enough to identify the developing phenomena in bubble flow structures and to investigate the void wave propagations, and the void distribution effect could be minimized by electrically shielding the guard electrodes. It was also designed so that the inherent errors due to the phase shifts between channels be negligible. Various features occurred in the transitional process of bubble flow could be objectively identified by introducing some statistical parameters evaluated from void signals. Two distinct modes of structural development in bubble flow were observed in the transitional process, and they are found to be much influenced by the initial bubble size. And the mechanism to govern BSFRT could be characterized by two ways depending on the developing modes of bubble flow

  12. Sea Lion Diet Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — California sea lions pup and breed at four of the nine Channel Islands in southern California. Since 1981, SWFSC MMTD has been conducting a diet study of sea lions...

  13. A Regulatory Network Involving β-Catenin, e-Cadherin, PI3k/Akt, and Slug Balances Self-Renewal and Differentiation of Human Pluripotent Stem Cells In Response to Wnt Signaling.

    Science.gov (United States)

    Huang, Tyng-Shyan; Li, Li; Moalim-Nour, Lilian; Jia, Deyong; Bai, Jian; Yao, Zemin; Bennett, Steffany A L; Figeys, Daniel; Wang, Lisheng

    2015-05-01

    The mechanisms underlying disparate roles of the canonical Wnt signaling pathway in maintaining self-renewal or inducing differentiation and lineage specification in embryonic stem cells (ESCs) are not clear. In this study, we provide the first demonstration that self-renewal versus differentiation of human ESCs (hESCs) in response to Wnt signaling is predominantly determined by a two-layer regulatory circuit involving β-catenin, E-cadherin, PI3K/Akt, and Slug in a time-dependent manner. Short-term upregulation of β-catenin does not lead to the activation of T-cell factor (TCF)-eGFP Wnt reporter in hESCs. Instead, it enhances E-cadherin expression on the cell membrane, thereby enhancing hESC self-renewal through E-cadherin-associated PI3K/Akt signaling. Conversely, long-term Wnt activation or loss of E-cadherin intracellular β-catenin binding domain induces TCF-eGFP activity and promotes hESC differentiation through β-catenin-induced upregulation of Slug. Enhanced expression of Slug leads to a further reduction of E-cadherin that serves as a β-catenin "sink" sequestering free cytoplasmic β-catenin. The formation of such a framework reinforces hESCs to switch from a state of temporal self-renewal associated with short-term Wnt/β-catenin activation to definitive differentiation. Stem Cells 2015;33:1419-1433. © 2015 AlphaMed Press.

  14. Slug flow transitions in horizontal gas/liquid two-phase flows. Dependence on channel height and system pressure for air/water and steam/water two-phase flows

    International Nuclear Information System (INIS)

    Nakamura, Hideo

    1996-05-01

    The slug flow transitions and related phenomena for horizontal two-phase flows were studied for a better prediction of two-phase flows that typically appear during the reactor loss-of-coolant accidents (LOCAs). For better representation of the flow conditions experimentally, two large-scaled facility: TPTF for high-pressure steam/water two-phase flows and large duct test facility for air/water two-phase flows, were used. The visual observation of the flow using a video-probe was performed in the TPTF experiments for good understanding of the phenomena. The currently-used models and correlations based mostly on the small-scale low-pressure experiments were reviewed and improved based on these experimental results. The modified Taitel-Dukler model for prediction of transition into slug flow from wavy flow and the modified Steen-Wallis correlation for prediction of onset of liquid entrainment from the interfacial waves were obtained. An empirical correlation for the gas-liquid interfacial friction factor was obtained further for prediction of liquid levels at wavy flow. The region of slug flow regime that is generally under influences of the channel height and system pressure was predicted well when these models and correlations were applied together. (author). 90 refs

  15. Sea level report

    International Nuclear Information System (INIS)

    Schwartz, M.L.

    1979-01-01

    Study of Cenozoic Era sea levels shows a continual lowering of sea level through the Tertiary Period. This overall drop in sea level accompanied the Pleistocene Epoch glacio-eustatic fluctuations. The considerable change of Pleistocene Epoch sea level is most directly attributable to the glacio-eustatic factor, with a time span of 10 5 years and an amplitude or range of approximately 200 m. The lowering of sea level since the end of the Cretaceous Period is attributed to subsidence and mid-ocean ridges. The maximum rate for sea level change is 4 cm/y. At present, mean sea level is rising at about 3 to 4 mm/y. Glacio-eustacy and tectono-eustacy are the parameters for predicting sea level changes in the next 1 my. Glacio-eustatic sea level changes may be projected on the basis of the Milankovitch Theory. Predictions about tectono-eustatic sea level changes, however, involve predictions about future tectonic activity and are therefore somewhat difficult to make. Coastal erosion and sedimentation are affected by changes in sea level. Erosion rates for soft sediments may be as much as 50 m/y. The maximum sedimentation accumulation rate is 20 m/100 y

  16. Salish Sea Genetics - Salish Sea genetic inventory

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Salish Sea comprises most of the Puget Sound water area. Marine species are generally assemblages of discrete populations occupying various ecological niches....

  17. Olfactory Memory Storage and/or Retrieval Requires the Presence of the Exact Tentacle Used During Memory Acquisition in the Terrestrial Slug Limax.

    Science.gov (United States)

    Koga, Yurika; Matsuo, Yuko; Matsuo, Ryota

    2016-02-01

    Terrestrial pulmonates can form odor-aversion memories once a food odor is presented in combination with an aversive stimulus. Most of the olfactory information ascends via a tentacular ganglion located in the tip of the two pairs of tentacles, and is then transmitted to the higher olfactory center, the procerebrum. The procerebrum is the locus of memory storage and has been shown to be necessary for odor-aversion learning. However, it is unknown whether the procerebrum is the sole locus in which the memory engram resides. By exploiting the regenerative ability of tentacles, here we investigated whether tentacles function merely in transmitting olfactory information to the procerebrum, or constitute a part of the memory engram. We showed that after removal of the tentacles used during memory acquisition, slugs were unable to retrieve the memory, even if these tentacles were regenerated sufficiently to subserve memory function. Our results support the view that tentacles are more than conduits of odor information; they also participate in the formation of the memory engram.

  18. Prediction of turbulent mixing rates of both gas and liquid phases between adjacent subchannels in a two-phase slug-churn flow

    International Nuclear Information System (INIS)

    Kawahara, A.; Sadatomi, M.; Tomino, T.; Sato, Y.

    1998-01-01

    This paper presents a slug-churn flow model for predicting turbulent mixing rates of both gas and liquid phase between adjacent subchannels in a BWR fuel rod bundle. In the model, the mixing rate of the liquid phase is calculated as the sum of the three components, i.e., turbulent diffusion, convective transfer and pressure difference fluctuations between the subchannels. The compenents of turbulent diffusion and convective transfer are calculated from Sadatomi et al.'s (1996) method, applicable to single-phase turbulent mixing by considering the effect of the increment of liquid velocity due to the presence of gas phase. The component of the pressure difference fluctuations is evaluated from a newly developed correlations. The mixing rate of the gas phase, on the other side, is calculated from a simple relation of mixing rate between gas and liquid phases. The validity of the proposed model has been confirmed with the turbulent mixing rates data of Rudzinski et al. as well as the present authors

  19. Prediction of gas and liquid turbulent mixing rates between rod bundle subchannels in a two-phase slug-churn flow

    International Nuclear Information System (INIS)

    Kawahara, Akimaro; Sadatomi, Michio; Tomino, Takayoshi

    2000-01-01

    This paper presents a slug-churn flow model for predicting turbulent mixing rates of both gas and liquid phases between adjacent subchannels in a BWR fuel rod bundle. In the model, the mixing rate of the liquid phase is calculated as the sum of the three components, i.e., turbulent diffusion, convective transfer and pressure difference fluctuations between the subchannels. The components of turbulent diffusion and convective transfer are calculated from Sadatomi et al.'s (1996) method, applicable to single-phase turbulent mixing, by considering the effect of the increment of liquid velocity due to the presence of gas phase. The component of the pressure difference fluctuations is evaluated from a newly developed correlation. The mixing rate of the gas phase, on the other side, is calculated from a simple relation of mixing rate between gas and liquid phases. The validity of the proposed model has been confirmed with the turbulent mixing rates data of Rudzinski et al. as well as the present authors. (author)

  20. Comparison of constant-rate pumping test and slug interference test results at the Hanford Site B pond multilevel test facility

    International Nuclear Information System (INIS)

    Spane, F.A. Jr.; Thorne, P.D.

    1995-10-01

    Pacific Northwest Laboratory (PNL), as part of the Hanford Site Ground-Water Surveillance Project, is responsible for monitoring the movement and fate of contamination within the unconfined aquifer to ensure that public health and the environment are protected. To support the monitoring and assessment of contamination migration on the Hanford Site, a sitewide 3-dimensional groundwater flow model is being developed. Providing quantitative hydrologic property data is instrumental in development of the 3-dimensional model. Multilevel monitoring facilities have been installed to provide detailed, vertically distributed hydrologic characterization information for the Hanford Site unconfined aquifer. In previous reports, vertically distributed water-level and hydrochemical data obtained over time from these multi-level monitoring facilities have been evaluated and reported. This report describes the B pond facility in Section 2.0. It also provides analysis results for a constant-rate pumping test (Section 3.0) and slug interference test (Section 4.0) that were conducted at a multilevel test facility located near B Pond (see Figure 1. 1) in the central part of the Hanford Site. A hydraulic test summary (Section 5.0) that focuses on the comparison of hydraulic property estimates obtained using the two test methods is also presented. Reference materials are listed in Section 6.0

  1. An analytic solution to the time-dependent first-daughter fission-product plateout problem for multi-region isothermal slug flow

    International Nuclear Information System (INIS)

    Durkee, J.W. Jr.; Lee, C.E.

    1985-01-01

    The time-dependent, axisymmetric, isothermal slug flow convective-diffusion equation with radioactive decay is solved analytically to predict the behavior of a first-daughter fission-product undergoing gaseous transport through multiple materials in a cylindrical pipe. The integration coefficients are determined using the Davidon variable metric minimization method. The behavior of fission-product material deposited on the conduit wall is described by a standard mass-transfer model. The time-dependent plateout rate behavior, determined previously for parent fission-product deposition, is again evident for daughter product plateout. Dominance of the daughter plateout by parent deposition characteristics is apparent. The determination of the daughter wall mass-transfer and diffusion coefficient using a least-squares analysis of measured data depends upon a reasonably low ratio of parent/daughter half-lives. This is illustrated with 137 Cs/ 137 Ba(=2x10 5 ) and 140 Ba/ 140 La(=7.6), where for 137 Cs/ 137 Ba the solution sensitivity to the 137 Ba deposition parameters is small and for 140 Ba/ 140 La a reasonable solution is readily obtained. (author)

  2. Wire-mesh sensor, ultrasound and high-speed videometry applied for the characterization of horizontal gas-liquid slug flow

    Science.gov (United States)

    Ofuchi, C. Y.; Morales, R. E. M.; Arruda, L. V. R.; Neves, F., Jr.; Dorini, L.; do Amaral, C. E. F.; da Silva, M. J.

    2012-03-01

    Gas-liquid flows occur in a broad range of industrial applications, for instance in chemical, petrochemical and nuclear industries. Correct understating of flow behavior is crucial for safe and optimized operation of equipments and processes. Thus, measurement of gas-liquid flow plays an important role. Many techniques have been proposed and applied to analyze two-phase flows so far. In this experimental research, data from a wire-mesh sensor, an ultrasound technique and high-speed camera are used to study two-phase slug flows in horizontal pipes. The experiments were performed in an experimental two-phase flow loop which comprises a horizontal acrylic pipe of 26 mm internal diameter and 9 m length. Water and air were used to produce the two-phase flow and their flow rates are separately controlled to produce different flow conditions. As a parameter of choice, translational velocity of air bubbles was determined by each of the techniques and comparatively evaluated along with a mechanistic flow model. Results obtained show good agreement among all techniques. The visualization of flow obtained by the different techniques is also presented.

  3. Contemporary Arctic Sea Level

    Science.gov (United States)

    Cazenave, A. A.

    2017-12-01

    During recent decades, the Arctic region has warmed at a rate about twice the rest of the globe. Sea ice melting is increasing and the Greenland ice sheet is losing mass at an accelerated rate. Arctic warming, decrease in the sea ice cover and fresh water input to the Arctic ocean may eventually impact the Arctic sea level. In this presentation, we review our current knowledge of contemporary Arctic sea level changes. Until the beginning of the 1990s, Arctic sea level variations were essentially deduced from tide gauges located along the Russian and Norwegian coastlines. Since then, high inclination satellite altimetry missions have allowed measuring sea level over a large portion of the Arctic Ocean (up to 80 degree north). Measuring sea level in the Arctic by satellite altimetry is challenging because the presence of sea ice cover limits the full capacity of this technique. However adapted processing of raw altimetric measurements significantly increases the number of valid data, hence the data coverage, from which regional sea level variations can be extracted. Over the altimetry era, positive trend patterns are observed over the Beaufort Gyre and along the east coast of Greenland, while negative trends are reported along the Siberian shelf. On average over the Arctic region covered by satellite altimetry, the rate of sea level rise since 1992 is slightly less than the global mea sea level rate (of about 3 mm per year). On the other hand, the interannual variability is quite significant. Space gravimetry data from the GRACE mission and ocean reanalyses provide information on the mass and steric contributions to sea level, hence on the sea level budget. Budget studies show that regional sea level trends over the Beaufort Gyre and along the eastern coast of Greenland, are essentially due to salinity changes. However, in terms of regional average, the net steric component contributes little to the observed sea level trend. The sea level budget in the Arctic

  4. Arctic Sea Level Reconstruction

    DEFF Research Database (Denmark)

    Svendsen, Peter Limkilde

    Reconstruction of historical Arctic sea level is very difficult due to the limited coverage and quality of tide gauge and altimetry data in the area. This thesis addresses many of these issues, and discusses strategies to help achieve a stable and plausible reconstruction of Arctic sea level from...... 1950 to today.The primary record of historical sea level, on the order of several decades to a few centuries, is tide gauges. Tide gauge records from around the world are collected in the Permanent Service for Mean Sea Level (PSMSL) database, and includes data along the Arctic coasts. A reasonable...... amount of data is available along the Norwegian and Russian coasts since 1950, and most published research on Arctic sea level extends cautiously from these areas. Very little tide gauge data is available elsewhere in the Arctic, and records of a length of several decades,as generally recommended for sea...

  5. SEA and planning

    DEFF Research Database (Denmark)

    Stoeglehner, G.; Brown, A.L.; Kørnøv, Lone

    2009-01-01

    , and the relationship of the SEA to the planning activity itself. This paper focuses on the influence that planners have in these implementation processes, postulating the hypothesis that these are key players in achieving effectiveness in SEA. Based upon implementation theory and empirical experience, the paper......As the field of strategic environmental assessment (SEA) has matured, the focus has moved from the development of legislation, guidelines and methodologies towards improving the effectiveness of SEA. Measuring and of course achieving effectiveness is both complex and challenging. This paper...

  6. Sea surface temperatures and salinities from platforms in the Barents Sea, Sea of Japan, North Atlantic Ocean, Philippine Sea, Red Sea, and the South China Sea (Nan Hai) from 1896-1950 (NODC Accession 0000506)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Surface temperatures and salinities were collected in the Barents Sea, Sea of Japan, North Atlantic Ocean, Philippine Sea, Red Sea, and South China Sea (Nan Hai)...

  7. Dilemmas in SEA application

    DEFF Research Database (Denmark)

    Lyhne, Ivar

    Dilemmas in SEA Application: The DK Energy SectorIvar Lyhne - lyhne@plan.aau.dk. Based on three years of collaborative research, this paper outlines dilemmas in the application of SEA in the strategic development of the Danish energy sector. The dilemmas are based on concrete examples from practice...

  8. Indicators and SEA

    DEFF Research Database (Denmark)

    Gao, Jingjing; Kørnøv, Lone; Christensen, Per

    Abstract: Indicators are widely used in SEA to measure, communicate and monitor impacts from a proposed policy, plan or programme, and can improve the effectiveness for the SEA by simplifying the complexity of both assessment and presentation. Indicators can be seen as part of the implementation...... and if the information requirement for different target groups is not addressed. Indicators are widely used in SEA to measure, communicate and monitor impacts from a proposed policy, plan or programme, and can improve the effectiveness for the SEA by simplifying the complexity of both assessment and presentation...... process helping to understand, communicate and, integrate important environmental issues in planning and decision-making. On the other hand, use of indicators can also limit SEA effectiveness, if the ones chosen are biased or limited, if the aggregation gives incorrect interpretation...

  9. A Regulatory Network Involving β‐Catenin, e‐Cadherin, PI3k/Akt, and Slug Balances Self‐Renewal and Differentiation of Human Pluripotent Stem Cells In Response to Wnt Signaling

    Science.gov (United States)

    Huang, Tyng‐Shyan; Li, Li; Moalim‐Nour, Lilian; Jia, Deyong; Bai, Jian; Yao, Zemin; Bennett, Steffany A. L.; Figeys, Daniel

    2015-01-01

    Abstract The mechanisms underlying disparate roles of the canonical Wnt signaling pathway in maintaining self‐renewal or inducing differentiation and lineage specification in embryonic stem cells (ESCs) are not clear. In this study, we provide the first demonstration that self‐renewal versus differentiation of human ESCs (hESCs) in response to Wnt signaling is predominantly determined by a two‐layer regulatory circuit involving β‐catenin, E‐cadherin, PI3K/Akt, and Slug in a time‐dependent manner. Short‐term upregulation of β‐catenin does not lead to the activation of T‐cell factor (TCF)‐eGFP Wnt reporter in hESCs. Instead, it enhances E‐cadherin expression on the cell membrane, thereby enhancing hESC self‐renewal through E‐cadherin‐associated PI3K/Akt signaling. Conversely, long‐term Wnt activation or loss of E‐cadherin intracellular β‐catenin binding domain induces TCF‐eGFP activity and promotes hESC differentiation through β‐catenin‐induced upregulation of Slug. Enhanced expression of Slug leads to a further reduction of E‐cadherin that serves as a β‐catenin “sink” sequestering free cytoplasmic β‐catenin. The formation of such a framework reinforces hESCs to switch from a state of temporal self‐renewal associated with short‐term Wnt/β‐catenin activation to definitive differentiation. Stem Cells 2015;33:1419–1433 PMID:25538040

  10. Caspian sea: petroleum challenges

    International Nuclear Information System (INIS)

    2005-01-01

    The Caspian sea is one of the world areas the most promising in terms of investments and petroleum development. This study presents the petroleum challenges generated by this hydrocarbons reserve. The first part discusses the juridical status (sea or lake), the petroleum and the gas reserves, the ecosystem and the today environment (fishing and caviar), the geostrategic situation and the transport of gas and oil. It provides also a chronology from 1729 to 2005, a selection of Internet sites, books and reports on the subject and identity sheets of the countries around the Caspian sea. (A.L.B.)

  11. Radionuclides in the sea

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1971-07-01

    Water covers a little more than two-thirds of the earth's surface. What is thrown into the sea from a ship may be washed up on a shore thousands of miles away; wastes discharged into the seas or into rivers flowing into them can affect marine life and possibly also the health of man. The study, prevention and control of pollution of the seas and oceans by radionuclides introduced as by-products of man's use of nuclear energy is thus of global interest. (author)

  12. Sea Scallop Survey

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The standardized NEFSC Sea Scallop Survey began in 1980 and has covered an area from Cape Hatteras to Georges Bank. The survey aims to determine the distribution and...

  13. Energy from sea water

    International Nuclear Information System (INIS)

    Ruberti, M.

    2000-01-01

    The devices to obtain energy from sea exploiting thermal gradient and wave motion are numerous and efficient. Costs are at present prohibitive in our country and the utilization cannot be possible [it

  14. Sea Ice Ecosystems

    Science.gov (United States)

    Arrigo, Kevin R.

    2014-01-01

    Polar sea ice is one of the largest ecosystems on Earth. The liquid brine fraction of the ice matrix is home to a diverse array of organisms, ranging from tiny archaea to larger fish and invertebrates. These organisms can tolerate high brine salinity and low temperature but do best when conditions are milder. Thriving ice algal communities, generally dominated by diatoms, live at the ice/water interface and in recently flooded surface and interior layers, especially during spring, when temperatures begin to rise. Although protists dominate the sea ice biomass, heterotrophic bacteria are also abundant. The sea ice ecosystem provides food for a host of animals, with crustaceans being the most conspicuous. Uneaten organic matter from the ice sinks through the water column and feeds benthic ecosystems. As sea ice extent declines, ice algae likely contribute a shrinking fraction of the total amount of organic matter produced in polar waters.

  15. Black Sea aerosols

    International Nuclear Information System (INIS)

    Hacisalihoglu, G.; Eliyakut, F.; Anwari, M.A.; Ataman, O.Y.; Balkas, T.I.; Tuncel, G.; Olmez, I.

    1991-01-01

    Shipboard, high volume air particulate samples were collected from the Black Sea atmosphere and analyzed by instrumental neutron activation analysis, atomic absorption spectrophotometry and ion chromatography for about 40 elements and ions. Concentrations of elements in the eastern and western parts of the Black Sea are different at the 95% confidence level, with lower concentrations in the eastern Black Sea. Back-trajectories and concentrations of elements in trajectory groups show that Europe accounts for more than 70% of the anthropogenic elements in the atmosphere. The average sulfate concentration was 7 μg/m 3 , which is comparable with rural sulfate levels in western Europe. Fluxes of elements from the atmosphere to the Black Sea are in good agreement with the results of similar flux calculations for other regions

  16. Pollution of Coastal Seas

    Indian Academy of Sciences (India)

    These are the things ideally required for locating industries also. The mega-cities .... waste water released into coastal seas raises the ambient temperature causing .... Problems of ozone holes and greenhouse gases were, perhaps, beyond ...

  17. Pollution of coastal seas

    Digital Repository Service at National Institute of Oceanography (India)

    Varkey, M.J.

    Pollution of various environments is a consequence of population growth and industrialisation. Coastal seas form part of marine environment and are very rich in minerals, crude oil fishes etc. They are also being used for disposal of wastes from...

  18. Oceanography of marginal seas

    Digital Repository Service at National Institute of Oceanography (India)

    DileepKumar, M.

    in the first two shallow seas are driven by surface densification following evaporation that in the latter is largely influenced by freshwater discharge from Irrawaddy and inflows across the Andaman Ridge from east Bay of Bengal. Biological productivity...

  19. South China Sea

    Science.gov (United States)

    Morton, Brian; Blackmore, Graham

    2001-01-01

    The South China Sea is poorly understood in terms of its marine biota, ecology and the human impacts upon it. What is known is most often contained in reports and workshop and conference documents that are not available to the wider scientific community. The South China Sea has an area of some 3.3 million km2 and depths range from the shallowest coastal fringe to 5377 m in the Manila Trench. It is also studded with numerous islets, atolls and reefs many of which are just awash at low tide. It is largely confined within the Tropic of Cancer and, therefore, experiences a monsoonal climate being influenced by the Southwest Monsoon in summer and the Northeast Monsoon in winter. The South China Sea is a marginal sea and, therefore, largely surrounded by land. Countries that have a major influence on and claims to the sea include China, Malaysia, the Philippines and Vietnam, although Thailand, Indonesia and Taiwan have some too. The coastal fringes of the South China Sea are home to about 270 million people that have had some of the fastest developing and most vibrant economies on the globe. Consequently, anthropogenic impacts, such as over-exploitation of resources and pollution, are anticipated to be huge although, in reality, relatively little is known about them. The Indo-West Pacific biogeographic province, at the centre of which the South China Sea lies, is probably the world's most diverse shallow-water marine area. Of the three major nearshore habitat types, i.e., coral reefs, mangroves and seagrasses, 45 mangrove species out of a global of 51, most of the currently recognised 70 coral genera and 20 of 50 known seagrass species have been recorded from the South China Sea. The island groups of the South China Sea are all disputed and sovereignty is claimed over them by a number of countries. Conflicts have in recent decades arisen over them because of perceived national rights. It is perhaps because of this that so little research has been undertaken on the South

  20. South China Sea

    Energy Technology Data Exchange (ETDEWEB)

    Morton, Brian [Hong Kong Univ., Swire Inst. of Marine Science, Hong Kong (China); Hong Kong Univ., Dept. of Ecology and Biodiversity, Hong Kong (China); Blackmore, Graham [Hong Kong Univ. of Science and Technology, Dept. of Biology, Hong Kong (China)

    2001-07-01

    The South China Sea is poorly understood in terms of its marine biota, ecology and the human impacts upon it. What is known is most often contained in reports and workshops and conference documents that are not available to the wider scientific community. The South China Sea has an area of some 3.3 million km{sup 2} and depths range from the shallowest coastal fringe to 5377m in the Manila Trench. It is also studded with numerous islets, atolls and reefs many of which are just awash at low tide. It is largely confined within the Tropic of Cancer and, therefore, experiences a monsoonal climate being influenced by the Southwest Monsoon in summer and the Northeast Monsoon in winter. The South China Sea is a marginal sea and, therefore, largely surrounded by land. Countries that have a major influence on and claims to the sea include China, Malaysia, the Philippines and Vietnam, although Thailand, Indonesia and Taiwan have some too. The coastal fringes of the South China Sea are home to about 270 million people that have had some of the fastest developing and most vibrant economics on the globe. Consequently, anthropogenic impacts, such as over-exploitation of resources and pollution, are anticipated to be huge although, in reality, relatively little is known about them. The Indo-West Pacific biogeographic province, at the centre of which the South China Sea lies, is probably the world's most diverse shallow-water marine area. Of three major nearshore habitat types, i.e., coral reefs, mangroves and seagrasses, 45 mangrove species out of a global total of 51, most of the currently recognised 70 coral genera and 20 of 50 known seagrass species have been recorded from the South China Sea. The island groups of the South China Sea are all disputed and sovereignty is claimed over them by a number of countries. Conflicts have in recent decades arisen over them because of perceived national rights. It is perhaps because of this that so little research has been undertaken

  1. South China Sea Dispute

    OpenAIRE

    Tanderup, Kasper Buch; Grinderslev, Emil Juhler; Tønnesen-Højbjerg, Asser Laurits Svend

    2017-01-01

    China is rising rapidly in terms of economics, military spending, sphere of influence and claims to in their view former territory. This paper has aimed to discuss the latter through analysis of the present dispute concerning islands and maritime territory in the South China Sea. The Chinese have become increasingly assertive in their claims formulated through a U-shaped line entailing most of the area within the South China Sea. The claims are contested by Vietnam, the Philippines, Indonesia...

  2. Contemporary sea level rise.

    Science.gov (United States)

    Cazenave, Anny; Llovel, William

    2010-01-01

    Measuring sea level change and understanding its causes has considerably improved in the recent years, essentially because new in situ and remote sensing observations have become available. Here we report on most recent results on contemporary sea level rise. We first present sea level observations from tide gauges over the twentieth century and from satellite altimetry since the early 1990s. We next discuss the most recent progress made in quantifying the processes causing sea level change on timescales ranging from years to decades, i.e., thermal expansion of the oceans, land ice mass loss, and land water-storage change. We show that for the 1993-2007 time span, the sum of climate-related contributions (2.85 +/- 0.35 mm year(-1)) is only slightly less than altimetry-based sea level rise (3.3 +/- 0.4 mm year(-1)): approximately 30% of the observed rate of rise is due to ocean thermal expansion and approximately 55% results from land ice melt. Recent acceleration in glacier melting and ice mass loss from the ice sheets increases the latter contribution up to 80% for the past five years. We also review the main causes of regional variability in sea level trends: The dominant contribution results from nonuniform changes in ocean thermal expansion.

  3. Ecoulements diphasiques gaz-liquide à poches et à bouchons en conduites Two-Phase Gas-Liquid Slug Flow in Pipes

    Directory of Open Access Journals (Sweden)

    Ferschneider G.

    2006-11-01

    Full Text Available Les écoulements diphasiques gaz-liquide ont été étudiés afin de contribuer à développer des modèles de calculs prédictifs des pertes de charge dans les conduites de production des bruts pétroliers. Les expériences nécessaires ont été réalisées sur la boucle diphasique de Boussens dans les conditions suivantes représentatives des conditions industrielles : diamètre 6 , longueur 120 m, disposition de la conduite horizontale ou faiblement ascendante, couple de fluide gaz naturel-huile légère. Le gradient de pression, le contenu global, et la distribution locale des phases ont été mesurés. Le traitement des équations de conservation phasique intégrées sur la section par différents types de moyennes a permis de développer un modèle cellulaire qui inclue un nombre limité d'équations constitutives nécessaires à sa fermeture. Ce modèle prédétermine convenablement le gradient de pression, le contenu gaz global et la longueur des poches et des bouchons. Two-phase gas-liquid flows were analyzed so as to develop models for prediction of pressure drops in crude-oil production lines. The experiments were performed on the two-phase loop at Boussens under the following representative industrial conditions: 6 diameter, 120 m length, horizontal or slightly rising pipe, couple of fluids natural gas and light oil. The pressure gradient, average content and local phase distribution were measured. Conservation phase equations integrated along the cross-section were processed by different time-averaged operators so as to develop a cellular model including a limited number of constitutive equations required for its closure. This model suitably predetermines the pressure gradient, the average gas content and the length of gas and liquid slug.

  4. Projecting future sea level

    Science.gov (United States)

    Cayan, Daniel R.; Bromirski, Peter; Hayhoe, Katharine; Tyree, Mary; Dettinger, Mike; Flick, Reinhard

    2006-01-01

    California’s coastal observations and global model projections indicate that California’s open coast and estuaries will experience increasing sea levels over the next century. Sea level rise has affected much of the coast of California, including the Southern California coast, the Central California open coast, and the San Francisco Bay and upper estuary. These trends, quantified from a small set of California tide gages, have ranged from 10–20 centimeters (cm) (3.9–7.9 inches) per century, quite similar to that estimated for global mean sea level. So far, there is little evidence that the rate of rise has accelerated, and the rate of rise at California tide gages has actually flattened since 1980, but projections suggest substantial sea level rise may occur over the next century. Climate change simulations project a substantial rate of global sea level rise over the next century due to thermal expansion as the oceans warm and runoff from melting land-based snow and ice accelerates. Sea level rise projected from the models increases with the amount of warming. Relative to sea levels in 2000, by the 2070–2099 period, sea level rise projections range from 11–54 cm (4.3–21 in) for simulations following the lower (B1) greenhouse gas (GHG) emissions scenario, from 14–61 cm (5.5–24 in) for the middle-upper (A2) emission scenario, and from 17–72 cm (6.7–28 in) for the highest (A1fi) scenario. In addition to relatively steady secular trends, sea levels along the California coast undergo shorter period variability above or below predicted tide levels and changes associated with long-term trends. These variations are caused by weather events and by seasonal to decadal climate fluctuations over the Pacific Ocean that in turn affect the Pacific coast. Highest coastal sea levels have occurred when winter storms and Pacific climate disturbances, such as El Niño, have coincided with high astronomical tides. This study considers a range of projected future

  5. The White Sea, Russia

    Science.gov (United States)

    2002-01-01

    Editor's Note: The caption below, published on May 10, 2001, is incorrect. According to Masha Vorontsova, director of the International Fund for Animal Welfare in Moscow, the situation with the seal pups in the White Sea is normal. There is no disaster and there never was. For more details, refer to the article entitled 'No Danger' on the New Scientist home page. The Earth Observatory regrets the earlier errant report. Original Caption According to the Russian Polar Research Institute for Fisheries and Oceanography, between 250,000 and 300,000 Greenland seal pups face death by starvation over the next two months due to a cruel trick by mother nature. The seals, most of them less than two months old, are trapped on ice sheets that remain locked in the White Sea, located near Archangel in Northern Russia. Typically, during the spring thaw the ice sheets break up and flow with the currents northward into the Barents Sea, the seals' spring feeding grounds. The seal pups hitch a ride on the ice floes, living on their own individual stores of fat until they arrive in the Barents Sea. Their mothers departed for the Barents Sea weeks ago. In a normal year, the seal pups' trip from the White Sea out to the Barents takes about six weeks and the seals have adapted to rely upon this mechanism of mother nature. During their yearly migration, the mother seals usually stay with their pups and feed them until their pelts turn from white to grey--a sign that the pups are mature enough to swim and feed themselves. Unfortunately, this year unusually strong northerly winds created a bottleneck of ice near the mouth of the white sea, thus blocking the flow of ice and trapping the pups. These true-color images of the White Sea were acquired by the Moderate-resolution Imaging Spectroradiometer (MODIS), flying aboard NASA's Terra spacecraft. This image, taken May 2, 2000 that there is usually much less ice in the White Sea this time of year as most of it is typically en route to the

  6. Numerical modelling of climate change impacts on freshwater lenses on the North Sea Island of Borkum

    Science.gov (United States)

    Sulzbacher, H.; Wiederhold, H.; Siemon, B.; Grinat, M.; Igel, J.; Burschil, T.; Günther, T.; Hinsby, K.

    2012-03-01

    A numerical variable-density groundwater model is set up for the North Sea Island of Borkum to estimate climate change impacts on coastal aquifers and especially the situation of barrier islands in the Wadden Sea. The database includes information from boreholes, a seismic survey, a helicopter-borne electromagnetic survey (HEM), monitoring of the freshwater-saltwater boundary by vertical electrode chains in two boreholes, measurements of groundwater table, pumping and slug tests, as well as water samples. Based on a statistical analysis of borehole columns, seismic sections and HEM, a hydrogeological model is set up. The groundwater model is developed using the finite-element programme FEFLOW. The variable-density groundwater model is calibrated on the basis of hydraulic, hydrological and geophysical data, in particular spatial HEM and local monitoring data. Verification runs with the calibrated model show good agreement between measured and computed hydraulic heads. A good agreement is also obtained between measured and computed density or total dissolved solids data for both the entire freshwater lens on a large scale and in the area of the well fields on a small scale. For simulating future changes in this coastal groundwater system until the end of the current century we use the climate scenario A2, specified by the Intergovernmental Panel on Climate Change and in particular the data for the German North Sea coast. Simulation runs show proceeding salinization with time beneath the well fields of the two waterworks Waterdelle and Ostland. The modelling study shows that spreading of well fields is an appropriate protection measure against excessive salinization of the water supply until the end of the current century.

  7. The Dead Sea

    Science.gov (United States)

    2006-01-01

    The Dead Sea is the lowest point on Earth at 418 meters below sea level, and also one of the saltiest bodies of water on Earth with a salinity of about 300 parts-per-thousand (nine times greater than ocean salinity). It is located on the border between Jordan and Israel, and is fed by the Jordan River. The Dead Sea is located in the Dead Sea Rift, formed as a result of the Arabian tectonic plate moving northward away from the African Plate. The mineral content of the Dead Sea is significantly different from that of ocean water, consisting of approximately 53% magnesium chloride, 37% potassium chloride and 8% sodium chloride. In the early part of the 20th century, the Dead Sea began to attract interest from chemists who deduced that the Sea was a natural deposit of potash and bromine. From the Dead Sea brine, Israel and Jordan produce 3.8 million tons potash, 200,000 tons elemental bromine, 45,000 tons caustic soda, 25, 000 tons magnesium metal, and sodium chloride. Both countries use extensive salt evaporation pans that have essentially diked the entire southern end of the Dead Sea. With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER images Earth to map and monitor the changing surface of our planet. ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products. The broad spectral coverage and high spectral resolution of ASTER provides scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining

  8. Unsteady jet-slug dynamics

    International Nuclear Information System (INIS)

    Kang, S.W.

    1977-01-01

    The present analysis treats the transient load characteristics at the wet-well bottom during the vent-clearing event under loss-of-coolant accident conditions. A conceptual model is introduced wherein the liquid-jet inertia and the net momentum-efflux are the two dominant physical factors. The derived load-history equations were found to be functions of the vent-clearing characteristics and of the jet-decay mode in the liquid pool. The theoretical results obtained by a physical modelling of these phenomena appear to agree reasonably well with the available data from UCLA and from LLL 1 / 5 -scale experiments

  9. Sea Spray Aerosols

    DEFF Research Database (Denmark)

    Butcher, Andrew Charles

    emissions produced directly from bubble bursting as the result of air entrainment from breaking waves and particles generated from secondary emissions of volatile organic compounds. In the first paper, we study the chemical properties of particles produced from several sea water proxies with the use...... of a cloud condensation nuclei ounter. Proxy solutions with high inorganic salt concentrations and some organics produce sea spray aerosol particles with little change in cloud condensation activity relative to pure salts. Comparison is made between a frit based method for bubble production and a plunging...... a relationship between plunging jet particle ux, oceanic particle ux, and energy dissipation rate in both systems. Previous sea spray aerosol studies dissipate an order of magnitude more energy for the same particle ux production as the open ocean. A scaling factor related to the energy expended in air...

  10. Replenishment at sea

    Directory of Open Access Journals (Sweden)

    Bohdan Pac

    2012-12-01

    Full Text Available Replenishment at sea is a process which plays the key role in the contemporary naval logistics during military and crisis operations. As the last element of the supply chain, it must use specific standards within the areas of procedures, technical equipment, logistic assets and resources, as well as safety, especially in multinational operations. The methods applied enable ships to operate at sea in the long term without logistic support provided by sea ports. The paper explains all the methods of the solids and liquids replenishment, and also gives an idea how to estimate the resupply process, using the measures. The level of standardization of procedures and assets implemented by NATO, the EU and other willing states has been described.

  11. Air-Sea Interaction

    Science.gov (United States)

    Csanady, G. T.

    2001-03-01

    In recent years air-sea interaction has emerged as a subject in its own right, encompassing small-scale and large-scale processes in both air and sea. Air-Sea Interaction: Laws and Mechanisms is a comprehensive account of how the atmosphere and the ocean interact to control the global climate, what physical laws govern this interaction, and its prominent mechanisms. The topics covered range from evaporation in the oceans, to hurricanes, and on to poleward heat transport by the oceans. By developing the subject from basic physical (thermodynamic) principles, the book is accessible to graduate students and research scientists in meteorology, oceanography, and environmental engineering. It will also be of interest to the broader physics community involved in the treatment of transfer laws, and thermodynamics of the atmosphere and ocean.

  12. Caribbean Sea Level Network

    Science.gov (United States)

    von Hillebrandt-Andrade, C.; Crespo Jones, H.

    2012-12-01

    Over the past 500 years almost 100 tsunamis have been observed in the Caribbean and Western Atlantic, with at least 3510 people having lost their lives to this hazard since 1842. Furthermore, with the dramatic increase in population and infrastructure along the Caribbean coasts, today, millions of coastal residents, workers and visitors are vulnerable to tsunamis. The UNESCO IOC Intergovernmental Coordination Group for Tsunamis and other Coastal Hazards for the Caribbean and Adjacent Regions (CARIBE EWS) was established in 2005 to coordinate and advance the regional tsunami warning system. The CARIBE EWS focuses on four areas/working groups: (1) Monitoring and Warning, (2) Hazard and Risk Assessment, (3) Communication and (4) Education, Preparedness and Readiness. The sea level monitoring component is under Working Group 1. Although in the current system, it's the seismic data and information that generate the initial tsunami bulletins, it is the data from deep ocean buoys (DARTS) and the coastal sea level gauges that are critical for the actual detection and forecasting of tsunamis impact. Despite multiple efforts and investments in the installation of sea level stations in the region, in 2004 there were only a handful of sea level stations operational in the region (Puerto Rico, US Virgin Islands, Bermuda, Bahamas). Over the past 5 years there has been a steady increase in the number of stations operating in the Caribbean region. As of mid 2012 there were 7 DARTS and 37 coastal gauges with additional ones being installed or funded. In order to reach the goal of 100 operational coastal sea level stations in the Caribbean, the CARIBE EWS recognizes also the importance of maintaining the current stations. For this, a trained workforce in the region for the installation, operation and data analysis and quality control is considered to be critical. Since 2008, three training courses have been offered to the sea level station operators and data analysts. Other

  13. Baltic Sea: Radionuclides

    DEFF Research Database (Denmark)

    Nielsen, Sven Poul; Lüning, Maria; Ilus, Erkki

    2011-01-01

    The most significant source of anthropogenic radioactivity in the Baltic Sea is fallout from the accident at the Chernobyl nuclear power plant in 1986. The second most important source is global fallout from atmospheric nuclear weapons tests carried out during the late 1950s and early 1960s...... about 14%. For 90Sr in the Baltic Sea, input from atmospheric fallout from nuclear weapons tests has contributed about 81%, while the contribution from Chernobyl fallout was about 13%. Cesium-137 is the main indicator of Baltic seawater with respect to anthropogenic radioactivity. The highest...... concentrations in seawater during 1999–2006 were found in the Baltic Proper and the Bothnian Sea. The general trend is steadily decreasing. Concentrations of anthropogenic radioactivity in fish generally show decreasing trends in agreement with concentrations in seawater. Among freshwater fish, pike showed large...

  14. Baltic Sea: Radionuclides

    DEFF Research Database (Denmark)

    Nielsen, Sven Poul; Lüning, Maria; Ilus, Erkki

    2010-01-01

    The most significant source of anthropogenic radioactivity in the Baltic Sea is fallout from the accident at the Chernobyl nuclear power plant in 1986. The second most important source is global fallout from atmospheric nuclear weapons tests carried out during the late 1950s and early 1960s...... about 14%. For 90Sr in the Baltic Sea, input from atmospheric fallout from nuclear weapons tests has contributed about 81%, while the contribution from Chernobyl fallout was about 13%. Cesium-137 is the main indicator of Baltic seawater with respect to anthropogenic radioactivity. The highest...... concentrations in seawater during 1999–2006 were found in the Baltic Proper and the Bothnian Sea. The general trend is steadily decreasing. Concentrations of anthropogenic radioactivity in fish generally show decreasing trends in agreement with concentrations in seawater. Among freshwater fish, pike showed large...

  15. Mediterranean, our sea

    Science.gov (United States)

    Markaki, Foteini

    2017-04-01

    My school (1o EPAL Ymittos -Athens, Greece) is a technical school of secondary education and throughout this school year being drafted a program of environmental education. The main theme is the Mediterranean Sea, the biggest closed sea extending between three continents. Topics studied: 1. Biodiversity and the risks threat. 2. The geophysics that characterize (earthquakes, volcanoes explosions, etc). 3. The Mediterranean Sea as environment anthropogenesis, a mosaic of other cultures and even place current notions of social phenomena (refugees). Pedagogical Objectives: Cognitive/Enviromental: 1. To investigate and understand the biodiversity of the Mediterranean Sea and the risks to threaten and phenomena that characterize. 2. To understand the position of the Mediterranean Sea in the land and the role of the historical, cultural and social human environment. 3. To come in contact with texts literary, social, articles on the Mediterranean. Psychomotor: 1. To work together and collect information for the Mediterranean Sea. 2. Experiential approach to the natural environment. 3. Develop critical thinking. 4. Undertake responsibilities for the presentation of the program. Emotional: 1. To feel joy from participation in the program. 2. Being sensitized and configure attitudes and actions of respect towards the environment. Methodology implementation: Teamwork. Interdisciplinary - holistic to dissemination of program recordings to courses curriculum. Study in the field. Gathering information from newspapers, magazines, internet, maps, and photographs. Experiential method- Project. Assessment methods and self-assessment. Fields of courses: Greek language- History- Biology- Chemistry- Technology Dissemination of results: Make a page of social media (facebook), a blog, enhancing environmental awareness via video, make an electronic poster.

  16. Air-sea exchange studies at the North Sea

    NARCIS (Netherlands)

    Leeuw, G. de; Eijk, A.M.J. van; Kunz, G.J.; Veefkind, P.J.

    1996-01-01

    The North Sea can be considered as a local 'inner' sea in which many processes are quite different from these over the open ocean. The surrounding land has a major influence, being the source for man-made aerosols and gases, whereas the North Sea acts as a sink for these. At the same time the North

  17. Phosphorus dynamics in the Black Sea and Baltic Sea

    NARCIS (Netherlands)

    Dijkstra, N.|info:eu-repo/dai/nl/372617034

    2017-01-01

    The dynamics of the key nutrient phosphorus (P) in hypoxic and anoxic marine basins are still incompletely understood. This thesis focuses on the cycling of P in two of such basins: the Baltic Sea and the Black Sea. Water column particulates and sediments from the deep basin of the Black Sea were

  18. Temperature measurement in the sea

    Digital Repository Service at National Institute of Oceanography (India)

    Krishnamacharyulu, R.J.; Rao, L.V.G.

    The importance of measuring sea temperature is explained and the various methods employed for this purpose are reviewed. Instruments used for spot measurement of water temperature at the sea surface and at discrete depths (bucket thermometer...

  19. Deep-sea fungi

    Digital Repository Service at National Institute of Oceanography (India)

    Raghukumar, C; Damare, S.R.

    significant in terms of carbon sequestration (5, 8). In light of this, the diversity, abundance, and role of fungi in deep-sea sediments may form an important link in the global C biogeochemistry. This review focuses on issues related to collection...

  20. The Dirac Sea

    OpenAIRE

    Dimock, J.

    2010-01-01

    We give an alternate definition of the free Dirac field featuring an explicit construction of the Dirac sea. The treatment employs a semi-infinite wedge product of Hilbert spaces. We also show that the construction is equivalent to the standard Fock space construction.

  1. Farming the Sea

    Science.gov (United States)

    Morgan, William

    1971-01-01

    Florida has initiated a training program in an entirely new dimension--Sea Farming. Presented is a description of the vocational agriculture program designed to teach propagation, cultivation, harvesting, marketing, and conservation practices related to production of oysters, shrimp, scallops, crabs, and fin fishes. (Editor/GB)

  2. Pollution around Malta's sea

    OpenAIRE

    Formosa, Nicolette

    2014-01-01

    Marine littering is a global concern and every single year tons of litter end up in the ocean all around the globe. It has become such a problem that the waste has amalgamated into huge ‘islands’ floating in the world’s oceans. http://www.um.edu.mt/think/pollution-around-maltas-sea/

  3. Wadden Sea Mud

    DEFF Research Database (Denmark)

    Møller-Jensen, P.

    The present thesis deals with the transport phenomena of estuarine cohesive sediment from a laboratory and a numerical point of view. The cohesive sediment used throughout the whole process was natural mud from the Danish part of the Wadden sea, Ho Bay. In the laboratory, the work was concentrated...

  4. Sea floor magnetic observatory

    Science.gov (United States)

    Korepanov, V.; Prystai, A.; Vallianatos, F.; Makris, J.

    2003-04-01

    The electromagnetic precursors of seismic hazards are widely accepted as strong evidence of the approaching earthquake or volcano eruption. The monitoring of these precursors are of main interest in densely populated areas, what creates serious problems to extract them at the strong industrial noise background. An interesting possibility to improve signal-to-noise ratio gives the installation of the observation points in the shelf zones near the possible earthquake places, what is fairly possible in most seismically active areas in Europe, e. g. in Greece and Italy. The serious restriction for this is the cost of the underwater instrumentation. To realize such experiments it requires the unification of efforts of several countries (e. g., GEOSTAR) or of the funds of some great companies (e. g., SIO magnetotelluric instrument). The progress in electronic components development as well as the appearance of inexpensive watertight glass spheres made it possible to decrease drastically the price of recently developed sea floor magnetic stations. The autonomous vector magnetometer LEMI-301 for sea bed application is described in the report. It is produced on the base of three-component flux-gate sensor. Non-magnetic housing and minimal magnetism of electronic components enable the instrument to be implemented as a monoblock construction where the electronic unit is placed close to the sensor. Automatic circuit provides convenient compensation of the initial field offset and readings of full value (6 digits) of the measured field. Timing by internal clock provides high accuracy synchronization of data. The internal flash memory assures long-term autonomous data storage. The system also has two-axes tilt measurement system. The methodological questions of magnetometer operation at sea bed were studied in order to avoid two types of errors appearing at such experimental cases. First is sea waving influence and second one magnetometer orientation at its random positioning on

  5. Slug Test Characterization Results for Multi-Test/Depth Intervals Conducted During the Drilling of CERCLA Operable Unit OU ZP-1 Wells 299-W11-43, 299-W15-50, and 299-W18-16

    Energy Technology Data Exchange (ETDEWEB)

    Spane, Frank A.; Newcomer, Darrell R.

    2010-06-21

    The following report presents test descriptions and analysis results for multiple, stress level slug tests that were performed at selected test/depth intervals within three Operable Unit (OU) ZP-1 wells: 299-W11-43 (C4694/Well H), 299-W15-50 (C4302/Well E), and 299-W18-16 (C4303/Well D). These wells are located within south-central region of the Hanford Site 200-West Area (Figure 1.1). The test intervals were characterized as the individual boreholes were advanced to their final drill depths. The primary objective of the hydrologic tests was to provide information pertaining to the areal variability and vertical distribution of hydraulic conductivity with depth at these locations within the OU ZP-1 area. This type of characterization information is important for predicting/simulating contaminant migration (i.e., numerical flow/transport modeling) and designing proper monitor well strategies for OU and Waste Management Area locations.

  6. Slug Test Characterization Results for Multi-Test/Depth Intervals Conducted During the Drilling of CERCLA Operable Unit OU UP-1 Wells 299-W19-48, 699-30-66, and 699-36-70B

    Energy Technology Data Exchange (ETDEWEB)

    Spane, Frank A.; Newcomer, Darrell R.

    2010-06-15

    This report presents test descriptions and analysis results for multiple, stress-level slug tests that were performed at selected test/depth intervals within three Operable Unit (OU) UP-1 wells: 299-W19-48 (C4300/Well K), 699-30-66 (C4298/Well R), and 699-36-70B (C4299/Well P). These wells are located within, adjacent to, and to the southeast of the Hanford Site 200-West Area. The test intervals were characterized as the individual boreholes were advanced to their final drill depths. The primary objective of the hydrologic tests was to provide information pertaining to the areal variability and vertical distribution of hydraulic conductivity with depth at these locations within the OU UP-1 area. This type of characterization information is important for predicting/simulating contaminant migration (i.e., numerical flow/transport modeling) and designing proper monitor well strategies for OU and Waste Management Area locations.

  7. The radioactivity of the sea

    International Nuclear Information System (INIS)

    Walker, M.I.; Rose, K.S.B.

    1990-01-01

    The radioactivity in the world's surface sea water averages 13.6 Bq/kg of water. Over 88% of this activity arises from a single natural radionuclide, 40 K, and 7% of the remainder results from nuclear weapon test fallout. Variations in the radioactivity occur due to changes in salinity, weapon test fallout and discharges of artificial radionuclides, and are examined here on the basis of published measurements. The most radioactive sea identified by these measurements is the Dead Sea, which averages 178 Bq/kg due to its high salinity. Other enclosed, highly saline waters can be expected to have similar levels. The radioactivity in open seas varies within a much narrower range, generally within 20% of the world average. The highest averages are found in the Persian Gulf (22 Bq/kg), the Red Sea (15 Bq/kg) and the Eastern Mediterranean (14.6 Bq/kg). The Irish Sea averaged 13.7 Bq/kg in 1987, with the effect of the Sellafield discharges being partly offset by lower than average salinity. Although higher levels occurred in the Irish Sea during the 1970s when the Sellafield discharges were higher, the average level has always been much less than that in the Dead Sea, so that the Irish Sea has never been the most radioactive sea in the world. Exceptionally low levels of radioactivity (4 Bq/kg) occur in the Baltic Sea due to dilution by fresh water. (author)

  8. Deep sea radionuclides

    International Nuclear Information System (INIS)

    Kanisch, G.; Vobach, M.

    1993-01-01

    Every year since 1979, either in sping or in summer, the fishing research vessel 'Walther Herwig' goes to the North Atlantic disposal areas of solid radioactive wastes, and, for comparative purposes, to other areas, in order to collect water samples, plankton and nekton, and, from the deep sea bed, sediment samples and benthos organisms. In addition to data on the radionuclide contents of various media, information about the plankton, nekton and benthos organisms living in those areas and about their biomasses could be gathered. The investigations are aimed at acquiring scientifically founded knowledge of the uptake of radioactive substances by microorganisms, and their migration from the sea bottom to the areas used by man. (orig.) [de

  9. Changing Sea Levels

    Science.gov (United States)

    Pugh, David

    2004-04-01

    Flooding of coastal communities is one of the major causes of environmental disasters world-wide. This textbook explains how sea levels are affected by astronomical tides, weather effects, ocean circulation and climate trends. Based on courses taught by the author in the U.K. and the U.S., it is aimed at undergraduate students at all levels, with non-basic mathematics being confined to Appendices and a website http://publishing.cambridge.org/resources/0521532183/.

  10. Sea Wind Europe

    International Nuclear Information System (INIS)

    2004-02-01

    The first and defining step towards European leadership in renewable energy must be the successful setting of an ambitious EU renewable energy target for 2020. This will set out the vision and create the framework within which our clean energy future can be delivered. Sea Wind Europe offers a clear blueprint of how to achieve its vision and outlines concrete policy measures that will give European renewables the foundation they need for success on a giant scale

  11. Black Sea challenges

    International Nuclear Information System (INIS)

    Drevet, J.F.

    2008-01-01

    In this month's European column, Jean-Francois Drevet examines the issues that arise for Europe from the Black Sea region. The Black Sea is increasingly becoming a crucial place of transit for hydrocarbon imports from the Caspian and Russia into the European Union. The considerable increase in this traffic raises both environmental problems (the risk of oil slicks) and issues of security of supply, on account of the economic and political fragility of some of the bordering or neighbouring states (Ukraine, Georgia, Armenia, Azerbaijan, Russia/Chechnya etc.). This is why, as Jean-Francois Drevet stresses, the European Union has been trying since the mid-1990's to claim a role in the management of the affairs of the region. With two bordering states (Rumania and Bulgaria) joining the EU in 2007, cooperation in the Black Sea has become a priority within the framework of the European Neighbourhood Policy, and this column delineates a number of the obstacles that still have to be surmounted. (author)

  12. Arctic landfast sea ice

    Science.gov (United States)

    Konig, Christof S.

    Landfast ice is sea ice which forms and remains fixed along a coast, where it is attached either to the shore, or held between shoals or grounded icebergs. Landfast ice fundamentally modifies the momentum exchange between atmosphere and ocean, as compared to pack ice. It thus affects the heat and freshwater exchange between air and ocean and impacts on the location of ocean upwelling and downwelling zones. Further, the landfast ice edge is essential for numerous Arctic mammals and Inupiat who depend on them for their subsistence. The current generation of sea ice models is not capable of reproducing certain aspects of landfast ice formation, maintenance, and disintegration even when the spatial resolution would be sufficient to resolve such features. In my work I develop a new ice model that permits the existence of landfast sea ice even in the presence of offshore winds, as is observed in mature. Based on viscous-plastic as well as elastic-viscous-plastic ice dynamics I add tensile strength to the ice rheology and re-derive the equations as well as numerical methods to solve them. Through numerical experiments on simplified domains, the effects of those changes are demonstrated. It is found that the modifications enable landfast ice modeling, as desired. The elastic-viscous-plastic rheology leads to initial velocity fluctuations within the landfast ice that weaken the ice sheet and break it up much faster than theoretically predicted. Solving the viscous-plastic rheology using an implicit numerical method avoids those waves and comes much closer to theoretical predictions. Improvements in landfast ice modeling can only verified in comparison to observed data. I have extracted landfast sea ice data of several decades from several sources to create a landfast sea ice climatology that can be used for that purpose. Statistical analysis of the data shows several factors that significantly influence landfast ice distribution: distance from the coastline, ocean depth, as

  13. Observational analysis of air-sea fluxes and sea water temperature offshore South China Sea

    Science.gov (United States)

    Bi, X.; Huang, J.; Gao, Z.; Liu, Y.

    2017-12-01

    This paper investigates the air-sea fluxes (momentum flux, sensible heat flux and latent heat flux) from eddy covariance method based on data collected at an offshore observation tower in the South China Sea from January 2009 to December 2016 and sea water temperature (SWT) on six different levels based on data collected from November 2011 to June 2013. The depth of water at the tower over the sea averages about 15 m. This study presents the in-situ measurements of continuous air-sea fluxes and SWT at different depths. Seasonal and diurnal variations in air-sea fluxes and SWT on different depths are examined. Results show that air-sea fluxes and all SWT changed seasonally; sea-land breeze circulation appears all the year round. Unlike winters where SWT on different depths are fairly consistent, the difference between sea surface temperature (SST) and sea temperature at 10 m water depth fluctuates dramatically and the maximum value reaches 7 °C during summer.

  14. Waste disposal into the sea

    International Nuclear Information System (INIS)

    Ehlers, P.; Kunig, P.

    1987-01-01

    The waste disposal at sea is regulated for the most part by national administrative law, which mainly is based on international law rules supplemented by EC-law. The dumping of low-level radioactive waste into the sea is more and more called into question. The disposal of high-level radioactive waste into the subsoil of the sea does not correspond to the London Convention. (WG) [de

  15. Air sea ratio reduction initiative

    Energy Technology Data Exchange (ETDEWEB)

    Oberle, Jean

    2010-09-15

    Airfreight is the most expensive mode of transportation as well as the most impacting in terms of CO{sup 2} emissions. It is 7 times more expensive on average to ship by air than shipping by sea 1. Airfreight transportation mode emits 30 times more CO{sup 2} than sea freight mode 2. These elements provided a compelling platform to design a global logistics program to initiate a modal shift from air to sea freight without compromising service to customers.

  16. The USGS Salton Sea Science Office

    Science.gov (United States)

    Case, Harvey Lee; Barnum, Douglas A.

    2007-01-01

    The U.S. Geological Survey's (USGS) Salton Sea Science Office (SSSO) provides scientific information and evaluations to decisionmakers who are engaged in restoration planning and actions associated with the Salton Sea. The primary focus is the natural resources of the Salton Sea, including the sea?s ability to sustain biological resources and associated social and economic values.

  17. Japan nuclear ship sea trial

    International Nuclear Information System (INIS)

    Yamazaki, Hiroshi; Kitamura, Toshikatus; Mizushima, Toshihiko

    1992-01-01

    The sea trial of the first Japan nuclear Ship 'MUTSU' was conducted from the end of October to December in 1990. The purpose of the sea trial was to verify the nuclear propulsive performances and maneuverabilities. The present report describes the results of the sea trial. These results are classified into four items: 1. Speed test and engineering performance tests 2. Maneuvering performance tests 3. Vibration tests 4. Other tests. Acceptable performances were demonstrated, as expected in the original design. The experience of the use of the Global Positioning System (GPS), which were newly adopted for the sea trial, is also reported. (author)

  18. Sea Urchin Morphogenesis.

    Science.gov (United States)

    McClay, David R

    2016-01-01

    In the sea urchin morphogenesis follows extensive molecular specification. The specification controls the many morphogenetic events and these, in turn, precede patterning steps that establish the larval body plan. To understand how the embryo is built it was necessary to understand those series of molecular steps. Here an example of the historical sequence of those discoveries is presented as it unfolded over the last 50 years, the years during which major progress in understanding development of many animals and plants was documented by CTDB. In sea urchin development a rich series of experimental studies first established many of the phenomenological components of skeletal morphogenesis and patterning without knowledge of the molecular components. The many discoveries of transcription factors, signals, and structural proteins that contribute to the shape of the endoskeleton of the sea urchin larva then followed as molecular tools became available. A number of transcription factors and signals were discovered that were necessary for specification, morphogenesis, and patterning. Perturbation of the transcription factors and signals provided the means for assembling models of the gene regulatory networks used for specification and controlled the subsequent morphogenetic events. The earlier experimental information informed perturbation experiments that asked how patterning worked. As a consequence it was learned that ectoderm provides a series of patterning signals to the skeletogenic cells and as a consequence the skeletogenic cells secrete a highly patterned skeleton based on their ability to genotypically decode the localized reception of several signals. We still do not understand the complexity of the signals received by the skeletogenic cells, nor do we understand in detail how the genotypic information shapes the secreted skeletal biomineral, but the current knowledge at least outlines the sequence of events and provides a useful template for future

  19. Sea Fighter Analysis

    Science.gov (United States)

    2007-02-01

    which is used by the model to drive the normal activities of the crew (Figure C.1-2). These routines consist of a sequential list of high- level...separately. Figure C.1-3: Resources & Logic Sheet C.1.1.4 Scenario The scenario that is performed during a model run is a sequential list of all...were marked with a white fore and aft lineup stripe on both landing spots. Current Sea Fighter design does not provide a hangar; however, there

  20. Beside the Sea

    Directory of Open Access Journals (Sweden)

    Véronique Olmi

    2012-01-01

    Full Text Available We are delighted to publish an extract from "Beside the Sea" by Véronique Olmi. Bord de Mer was first published in 2001 by Peirene Press which is an award-winning, independent publishing house. It specializes in contemporary European literature in English translation. Peirene's books are all under 200 pages and can be read in the same time it takes to watch a DVD. Peirene's authors are award-winners and bestsellers in their own countries. 'Two-hour-books to be devoured in a single sitting: literary cinema for those fatigued by film.' Times Literary Supplement. www.peirenepress.com

  1. The Arabian Sea

    Digital Repository Service at National Institute of Oceanography (India)

    Naqvi, S.W.A.; Naik, H.; Narvekar, P.V.

    high chI are also encountered offshore, presumably associated with the mesoscale features such as filaments and eddies. In conformity with the satellite data, elevated chI levels persist~lOOOkmfrom the Omani coast. During the Sl, chI levels are quite... is consumed rapidly for the degradation of copious amounts of organic matter produced within the Arabian Sea itself. Consequently, 02 levels fall very close to zero while nutrients accumulate in high concentrations within a zone that extends from the base...

  2. Polarimetric signatures of sea ice in the Greenland Sea

    DEFF Research Database (Denmark)

    Skriver, Henning; Pedersen, Leif Toudal

    1995-01-01

    Polarimetric SAR data of sea ice have been acquired by the Danish polarimetric SAR (EMISAR) during a mission at the Greenland Sea in August 1994. Video recordings from a low-altitude acquisition have been used for interpretation of the SAR data. Also, ERS-1 SAR data and NOAA AVHRR-data have been...

  3. Investigating Arctic Sea Ice Survivability in the Beaufort Sea

    Directory of Open Access Journals (Sweden)

    Matthew Tooth

    2018-02-01

    Full Text Available Arctic sea ice extent has continued to decline in recent years, and the fractional coverage of multi-year sea ice has decreased significantly during this period. The Beaufort Sea region has been the site of much of the loss of multi-year sea ice, and it continues to play a large role in the extinction of ice during the melt season. We present an analysis of the influence of satellite-derived ice surface temperature, ice thickness, albedo, and downwelling longwave/shortwave radiation as well as latitude and airborne snow depth estimates on the change in sea ice concentration in the Beaufort Sea from 2009 to 2016 using a Lagrangian tracking database. Results from this analysis indicate that parcels that melt during summer in the Beaufort Sea reside at lower latitudes and have lower ice thickness at the beginning of the melt season in most cases. The influence of sea ice thickness and snow depth observed by IceBridge offers less conclusive results, with some years exhibiting higher thicknesses/depths for melted parcels. Parcels that melted along IceBridge tracks do exhibit lower latitudes and ice thicknesses, however, which indicates that earlier melt and breakup of ice may contribute to a greater likelihood of extinction of parcels in the summer.

  4. Deep sea biophysics

    International Nuclear Information System (INIS)

    Yayanos, A.A.

    1982-01-01

    A collection of deep-sea bacterial cultures was completed. Procedures were instituted to shelter the culture collection from accidential warming. A substantial data base on the rates of reproduction of more than 100 strains of bacteria from that collection was obtained from experiments and the analysis of that data was begun. The data on the rates of reproduction were obtained under conditions of temperature and pressure found in the deep sea. The experiments were facilitated by inexpensively fabricated pressure vessels, by the streamlining of the methods for the study of kinetics at high pressures, and by computer-assisted methods. A polybarothermostat was used to study the growth of bacteria along temperature gradients at eight distinct pressures. This device should allow for the study of microbial processes in the temperature field simulating the environment around buried HLW. It is small enough to allow placement in a radiation field in future studies. A flow fluorocytometer was fabricated. This device will be used to determine the DNA content per cell in bacteria grown in laboratory culture and in microorganisms in samples from the ocean. The technique will be tested for its rapidity in determining the concentration of cells (standing stock of microorganisms) in samples from the ocean

  5. Reactors at sea

    International Nuclear Information System (INIS)

    Hines, Colin

    1988-01-01

    The Greenpeace Nuclear Free Seas Campaign is outlined. The campaign aims to bring the environmental hazards from nuclear submarines and naval ships carrying nuclear weapons to public attention. Worldwide there are 544 nuclear reactor ships or submarines each with the potential to meltdown with serious environmental consequences. One meltdown is known to have occurred. Five reactors have been abandoned on the sea bed. Nuclear powered submarines are based at Rosyth, Faslane, Holy Loch, Plymouth and Portsmouth and routinely come into and out of those harbours. There have also been accidents involving nuclear weapons on board submarines, aircraft carriers or destroyers which carry nuclear depth bombs and free fall bombs. The Royal Navy's accident emergency plans for nuclear naval bases are inadequate. There is a threat to the environment when the reactors are decommissioned. There are no clear plans as to how to deal with the decommissioning of the submarines or ships although the fuel rods have been removed from the first British nuclear submarine, Dreadnought. (U.K.)

  6. Intraseasonal sea surface temperature variability in Indonesian seas

    Science.gov (United States)

    Napitu, A. M.; Gordon, A. L.; Yuan, X.

    2012-12-01

    The satellite-derived sea surface temperature (SST) data, 1998-mid 2012, are used to examine intraseasonal variability (ISV; 20-90 days) across the Indonesian seas. The most energetic ISV is observed in the Banda Sea and across the Indo-Australia basin with an The satellite-derived sea surface temperature (SST) data, 1998-mid 2012, are used to examine intraseasonal variability (ISV; 20-90 days) across the Indonesian seas. The most energetic ISV is observed in the Banda Sea and across the Indo-Australia basin with an average SST standard deviation (STD) between 0.4-0.5°C, with strongest signature during boreal winter. What physical processes force the SST ISV variability within the Indonesian seas? Ocean process, sea-air interaction, or both? To help identify the main forcing, the satellite derived outgoing longwave radiation (OLR) and wind stress data in the region are examined. The OLR shows robust intraseasonal variations and is significantly correlated with the SST, particularly for variability with periods of 30-60 days, with OLR accounting for ~60-70% of the SST variance. The OLR is also maximum during boreal winter. Conversely, the surface wind may play insignificant role in perturbing the SST at intraseasonal timescales as shown by weak correlation between wind stress and SST. We thus suspect that the surface solar flux (suggested by the OLR) is likely more dominant than the surface turbulent heat flux (indicated by the surface wind) as the main source for the ISV in the SST in Indonesian seas. Furthermore the maximum OLR phase, coupled with a period of minimum mixed layer depth, may explain the strong SST variation during boreal winter in Indonesian seas. The influence of the Madden-Julian Oscillation (MJO) on the OLR and SST variability is currently being evaluated.

  7. Governance of the Wadden Sea

    NARCIS (Netherlands)

    Slob, Adriaan F.L.; Geerdink, T.R.A.; Rockmann, Christine; Vöge, S.

    2016-01-01

    The Wadden Sea is a unique area from ecological, geological and cultural perspectives and lies in the territories of Denmark, Germany and the Netherlands. The trilateral cooperation on the protection of the Wadden Sea can be marked to start in 1978, although the countries already cooperated

  8. Sea Level Rise Data Discovery

    Science.gov (United States)

    Quach, N.; Huang, T.; Boening, C.; Gill, K. M.

    2016-12-01

    Research related to sea level rise crosses multiple disciplines from sea ice to land hydrology. The NASA Sea Level Change Portal (SLCP) is a one-stop source for current sea level change information and data, including interactive tools for accessing and viewing regional data, a virtual dashboard of sea level indicators, and ongoing updates through a suite of editorial products that include content articles, graphics, videos, and animations. The architecture behind the SLCP makes it possible to integrate web content and data relevant to sea level change that are archived across various data centers as well as new data generated by sea level change principal investigators. The Extensible Data Gateway Environment (EDGE) is incorporated into the SLCP architecture to provide a unified platform for web content and science data discovery. EDGE is a data integration platform designed to facilitate high-performance geospatial data discovery and access with the ability to support multi-metadata standard specifications. EDGE has the capability to retrieve data from one or more sources and package the resulting sets into a single response to the requestor. With this unified endpoint, the Data Analysis Tool that is available on the SLCP can retrieve dataset and granule level metadata as well as perform geospatial search on the data. This talk focuses on the architecture that makes it possible to seamlessly integrate and enable discovery of disparate data relevant to sea level rise.

  9. Sea level and climate variations

    NARCIS (Netherlands)

    Oerlemans, J.

    1985-01-01

    Review paper, ESA Symposium on Application of Satellite Data to Climate Modelling. Alpbach (Austria) Sea level is an essential component of the climate system, on which many human activities in the coastal zone depend. Climate variations leading to changes in relative sea level are

  10. The Barbados Sea Level Record

    Science.gov (United States)

    Fairbanks, R. G.; Mortlock, R. A.; Abdul, N. A.; Wright, J. D.; Cao, L.; Mey, J. L.

    2013-12-01

    Additional offshore drill cores, nearly 100 new radiometric dates, and more than 1000 kilometers of Multibeam mapping greatly enhance the Barbados Sea Level record. Extensive Multibeam mapping around the entire island covers approximately 2650 km2 of the sea bottom and now integrates the offshore reef topography and Barbados Sea Level Record with the unparalleled onshore core collection, digital elevation maps, and Pleistocene sea level record spanning the past one million years. The reef crest coral, Acropora palmata, remains the stalwart indicator of sea level for many reasons that are validated by our redundant sea level records and redundant dating via Th/U and Pa/U analyses. Microanalysis and densitometry studies better explain why Acropora palmata is so well preserved in the Pleistocene reef records and therefore why it is the species of choice for sea level reconstructions and radiometric dating. New drill cores into reefs that formed during Marine Isotope Stage 3 lead us to a model of diagenesis that allows us to better prospect for unaltered coral samples in older reefs that may be suitable for Th/U dating. Equally important, our diagenesis model reinforces our rigorous sample quality criteria in a more quantitative manner. The Barbados Sea Level record has a sampling resolution of better than 100 years throughout much of the last deglaciation showing unprecedented detail in redundant drill cores. The Melt Water Pulses (MWP1A and MWP1B) are well resolved and the intervening interval that includes the Younger Dryas reveals sea level changes in new detail that are consistent with the terrestrial records of ice margins (see Abdul et al., this section). More than 100 paired Th/U and radiocarbon ages place the Barbados Sea Level Record unambiguously on the radiocarbon time scale for direct comparisons with the terrestrial records of ice margin changes.

  11. Highly variable Pliocene sea surface conditions in the Norwegian Sea

    Directory of Open Access Journals (Sweden)

    P. E. Bachem

    2017-09-01

    Full Text Available The Pliocene was a time of global warmth with small sporadic glaciations, which transitioned towards the larger-scale Pleistocene glacial–interglacial variability. Here, we present high-resolution records of sea surface temperature (SST and ice-rafted debris (IRD in the Norwegian Sea from 5.32 to 3.14 Ma, providing evidence that the Pliocene surface conditions of the Norwegian Sea underwent a series of transitions in response to orbital forcing and gateway changes. Average SSTs are 2 °C above the regional Holocene mean, with notable variability on millennial to orbital timescales. Both gradual changes and threshold effects are proposed for the progression of regional climate towards the Late Pliocene intensification of Northern Hemisphere glaciation. Cooling from 4.5 to 4.3 Ma may be linked to the onset of poleward flow through the Bering Strait. This cooling was further intensified by a period of cool summers due to weak obliquity forcing. A 7 °C warming of the Norwegian Sea at 4.0 Ma suggests a major increase in northward heat transport from the North Atlantic, leading to an enhanced zonal SST gradient in the Nordic Seas, which may be linked to the expansion of sea ice in the Arctic and Nordic Seas. A warm Norwegian Sea and enhanced zonal temperature gradient between 4.0 and 3.6 Ma may have been a priming factor for increased glaciation around the Nordic Seas due to enhanced evaporation and precipitation at high northern latitudes.

  12. Uranium from sea water

    International Nuclear Information System (INIS)

    Westermark, T.; Forsberg, S.

    1980-01-01

    The prevalent situation in the field of uranium extraction from the oceans was reviewed from a scientific and technological standpoint and as to legality too. No international convention seems to limit the access to dissolved or suspended matter in free area of the oceans. All publications received through 1979 point to adsorption as the method of choice, at some form of hydrated titanium ''oxide'' as the most promising sorbent, and, generally spoken, at the cost of pumping water through the contacting system as a huge economical problem. A recent Swedish invention may circumvent the pumping problem by making available, in a previously unknown manner, some kind of self-renewing energy from the oceans. A simple economic calculus has resulted in costs from two to six times the present world market price of crude uranium oxide (which is assumed to be US dollar 43.-/1b), with a possibility to compete really after some technical and systematic developments. Results from a small-scale adsorption experiment in genuine sea water are presented: During a few weeks sea water was pumped through tiny, 10 cm high beds of sodium titanate ion exchangers, partly in the hydrogen form. The grain size was 250-500 μm, the flow rate 0.15-0.61 m/min. About 5% of the total amount of uranium passing the columns was retained, resulting in 8-11 μg/Ug. Also, large amounts of manganese, strontium, vanadium and zink were retained. Some of these elements and plankton as well may perhaps be recovered with an economic gain

  13. Slug-Burst Detection in the G3 Reactor; La detection de rupture de gaine au reacteur G3; Obnaruzhenie razryva obolochki v reaktore G3; Deteccion de fallas del revestimiento en el reactor G3

    Energy Technology Data Exchange (ETDEWEB)

    Plisson, J. [Centre d' Etudes Nucleaires de Marcoule (France)

    1963-10-15

    The author explains the principles underlying slug-burst detection and describes the construction of the apparatus concerned. The main features are a) fully automatic operation, b) centralization of data in the control room and c) measurement by electrostatic collection on a turntable. (author) [French] Dans ce memoire, l'auteur expose les principes sur lesquels est fondee la detection de rupture de gaines et il decrit la realisation des installations. Les caracteristiques principales sont a) l'automatisme integral, b) la centralisation des informations dans la salle de commande et c) mesure par collection electrostatique sur plaque tournante. (author) [Spanish] El autor expone los principios en que se basa la deteccion de las fallas en los revestimientos de los elementos combustibles y describe las caracteristicas principales de la instalacion, que son: a) automatizacion integral, b) centralizacion de las informaciones en la sala de mandos, y c) medicion por recoleccion electrostatica sobre una placa giratoria. (author) [Russian] Izlagayutsya printsipy, na kotorykh osnovano obnaruzhenie razryva obolochki, opisyvaetsya konstruirovanie ustanovok. Osnovnye kharakteristiki takovy: a) integral'nyj avtomatizm, b) tsentralizatsiya informatsii v komandnom zale i c) izmerenie putem ehlektrostaticheskogo sobiraniya na povorachivayushchejsya plastinke. (author)

  14. Integrating out the Dirac sea

    International Nuclear Information System (INIS)

    Karbstein, Felix

    2009-01-01

    We introduce a new method for dealing with fermionic quantum field theories amenable to a mean-field-type approximation. In this work we focus on the relativistic Hartree approximation. Our aim is to integrate out the Dirac sea and derive a no-sea effective theory'' with positive energy single particle states only. As the derivation of the no-sea effective theory involves only standard Feynman diagrams, our approach is quite general and not restricted to particular space-time dimensions. We develop and illustrate the approach in the ''large N'' limit of the Gross-Neveu model family in 1+1 dimensions. As the Gross-Neveu model has been intensely studied and several analytical solutions are known for this model, it is an ideal testing ground for our no-sea effective theory approach. The chiral Gross-Neveu model, also referred to as 1+1 dimensional Nambu-Jona-Lasinio model, turns out to be of particular interest. In this case, we explicitly derive a consistent effective theory featuring both elementary ''π meson'' fields and (positive energy) ''quark'' fields, starting from a purely fermionic quantum field theory. In the second part of this work, we apply our approach to the Walecka model in 1+1 and 3+1 dimensions. As the Dirac sea caused considerable difficulties in attempts to base nuclear physics on field theoretic models like the Walecka model, mean-field calculations were typically done without the sea. We confront several of these mean-field theory results with our no-sea effective theory approach. The potential of our approach is twofold. While the no-sea effective theory can be utilized to provide new analytical insights in particular parameter regimes, it also sheds new light on more fundamental issues as the explicit emergence of effective, Dirac-sea induced multi-fermion interactions in an effective theory with positive energy states only. (orig.)

  15. Deep-sea geohazards in the South China Sea

    Science.gov (United States)

    Wu, Shiguo; Wang, Dawei; Völker, David

    2018-02-01

    Various geological processes and features that might inflict hazards identified in the South China Sea by using new technologies and methods. These features include submarine landslides, pockmark fields, shallow free gas, gas hydrates, mud diapirs and earthquake tsunami, which are widely distributed in the continental slope and reefal islands of the South China Sea. Although the study and assessment of geohazards in the South China Sea came into operation only recently, advances in various aspects are evolving at full speed to comply with National Marine Strategy and `the Belt and Road' Policy. The characteristics of geohazards in deep-water seafloor of the South China Sea are summarized based on new scientific advances. This progress is aimed to aid ongoing deep-water drilling activities and decrease geological risks in ocean development.

  16. Chemical oceanography of the Arabian Sea Part iv Laccadive sea

    Digital Repository Service at National Institute of Oceanography (India)

    SenGupta, R.; Moraes, C.; Kureishy, T.W.; Sankaranarayanan, V.N.; Jana, T.K.; Naqvi, S.W.A.; Rajagopal, M.D

    Patterns of distribution of nutrients and nutrients-oxygen relationships are similar to those observed in other parts of the Arabian Sea High magnesium and low fluoride concentrations in the water indicate probable loss of the latter as insoluble ion...

  17. Sea dumping of hazardous wastes

    International Nuclear Information System (INIS)

    Thomas, J.

    1980-01-01

    From 1967 until 1976 ca. 45,000 t of weak radioactive wastes had been dumped into the sea during several actions under the supervision of the NEA. The requirements to be deduced from the experiences with regard to marine areas, packaging and transports of the wastes are described. Up to now the possibilities of the sea dumping of strong radioactive wastes has been just discussed. The natural removal of the decay heat by sea water would be advantageous but the problem of water-proof packagings for the period of 1000 years have not been solved yet. (orig.) [de

  18. Discriminating Sea Spikes in Incoherent Radar Measurements of Sea Clutter

    Science.gov (United States)

    2008-03-01

    het detecteren echter niet te verwachten dat bet gebruik van sea spikes te onderzoeken. Een van deze modellen zal leiden tot een Auteur (s) dergelijk...report I TNO-DV 2008 A067 6/33 Abbreviations CFAR Constant False-Alarm Rate CST Composite Surface Theory FFT Fast Fourier Transform PDF Probability Density...described by the composite surface theory (CST). This theory describes the sea surface as small Bragg-resonant capillary waves riding on top of

  19. Eustatic and Relative Sea Level Changes

    NARCIS (Netherlands)

    Rovere, A.; Stocchi, P.; Vacchi, M.

    2016-01-01

    Sea level changes can be driven by either variationsin the masses or volume of the oceans, or bychanges of the land with respect to the sea surface. Inthe first case, a sea level change is defined ‘eustatic’;otherwise, it is defined ‘relative’. Several techniques canbe used to observe changes in sea

  20. ISLSCP II Sea Surface Temperature

    Data.gov (United States)

    National Aeronautics and Space Administration — Sea surface temperature (SST) is an important indicator of the state of the earth climate system as well as a key variable in the coupling between the atmosphere and...

  1. Black Sea Bass genetic connectivity

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Microsatellite analysis of black sea bass was undertaken to determine magnitude and direction of mixing of black seabass across the Hatteras boundary, as well as...

  2. Sea Turtle Acoustic Telemetry Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Acoustic transmitters attached to sea turtles captured in various fishing gear enable the animals to be passively tracked. Acoustic receivers set up in an array...

  3. Sea Turtle Radio Telemetry Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Radio transmitters attached to sea turtles captured in various fishing gear enabled us to track and measure surfacing time of each turtle. Determining location of...

  4. Sea Turtle Satellite Telemetry Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sea turtles captured in various fishing gear (pound nets, long haul seines, gill nets) were outfitted with satellite transmitters so that their movements, migratory...

  5. Sea bed mapping and inspection

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The conference has 24 presentations on the topics: Sea bed mapping, inspection, positioning, hydrography, marine archaeology, remote operation vehicles and computerized simulation technologies, oil field activities and plans, technological experiences and problems. (tk)

  6. Sea Turtle Stranding Network Reports

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Sea Turtle Stranding and Salvage Network (STSSN) was formally established in 1980 to collect information on and document the stranding of marine turtles along...

  7. Metals extraction from sea water

    International Nuclear Information System (INIS)

    Chryssostomidis, C.; Larue, G.J.; Morgan, D.T.

    1981-01-01

    A method and system for continuously extracting metals from sea water by deploying adsorber sheets in a suitable current of sea water, recovering the adsorber sheets after they become loaded with metal and eluting the metal from the recovered sheets. The system involves the use of hollow, perforated bobbins on which the sheets are rolled as they are recovered and through which elutant is introduced

  8. Intermittent sea-level acceleration

    Science.gov (United States)

    Olivieri, M.; Spada, G.

    2013-10-01

    Using instrumental observations from the Permanent Service for Mean Sea Level (PSMSL), we provide a new assessment of the global sea-level acceleration for the last ~ 2 centuries (1820-2010). Our results, obtained by a stack of tide gauge time series, confirm the existence of a global sea-level acceleration (GSLA) and, coherently with independent assessments so far, they point to a value close to 0.01 mm/yr2. However, differently from previous studies, we discuss how change points or abrupt inflections in individual sea-level time series have contributed to the GSLA. Our analysis, based on methods borrowed from econometrics, suggests the existence of two distinct driving mechanisms for the GSLA, both involving a minority of tide gauges globally. The first effectively implies a gradual increase in the rate of sea-level rise at individual tide gauges, while the second is manifest through a sequence of catastrophic variations of the sea-level trend. These occurred intermittently since the end of the 19th century and became more frequent during the last four decades.

  9. Alien seas oceans in space

    CERN Document Server

    Lopes, Rosaly

    2013-01-01

    In the early days of planetary observation, oceans were thought to exist in all corners of the Solar System. Carbonated seas percolated beneath the clouds of Venus. Features on the Moon's surface were given names such as "the Bay of Rainbows” and the "Ocean of Storms." With the advent of modern telescopes and spacecraft exploration these ancient concepts of planetary seas have been replaced by the reality of something even more exotic. Alien Seas serves up the current research, past beliefs, and new theories to offer a rich array of the "seas" on other worlds. It is organized by location and by the material composing the oceans under discussion, with expert authors penning chapters on their  specialty. Each chapter features new original art depicting alien seas, as well as the latest ground-based and spacecraft images. With the contributors as guides, readers can explore the wild seas of Jupiter's watery satellite Europa, believed similar in composition to battery acid. Saturn's planet-sized moon Titan see...

  10. Past and present Aral Sea

    Science.gov (United States)

    Dukhovniy, Viktor; Stulina, Galina; Eshchanov, Odylbek

    2013-04-01

    The tragedy of disappearing of Aral Sea is well known to the World. Before and after collapse of Soviet Union, a huge quantity of scientific and popular editions described with grief the situation around the Aral Sea. After the NIS states became independent, World Bank, UNDP, UNEP in proper competition with each other had provided some assessment of the situation through presentation of some small and medium grants, but after 2000, the local population remained alone with own problems. Although on the eyes of the present generation a unique transformation of great water body into deserts took place, the global scientific community did not find forces and financing for real and detail investigation of the processes accompanying the Sea shrinking and land formation. We should acknowledge and give big respect to NATO, later to German Government that through GTZ (now GIZ) - German International Collaboration Agency - and GFZ (Potzdam) paid attention to this area of environment crisis and organized scientific and protective design in the so-called Priaralie - the territory around the drying Sea and delta of the two rivers - Amudarya and Syrdarya. Thank to this assistance, the local specialists in collaboration with limited a number of foreign scientists (N.Aladin, P.Zavialov, Joop de Schutter, Hans Wilps, Hedi Oberhansli) organized significant works for detail socioeconomic, ecological and hydrological assessment situation in Priaralie and on the Aral sea coast. On this base, Ministry of Agriculture and Water resources of Uzbekistan and State Committee of Water resources of Kazakhstan developed a plan of rehabilitation of Amudarya and Syrdarya deltas and started implementation of these projects. If Kazakh water authority moved ahead in wetland restoration faster, a forestation of delta and drying bed of Aral Sea got big success in Uzbek territory. 244 thousands hectares of saxsaul and tamarix were planted for protection of the Priaralie. By request of GTZ SIC, ICWC

  11. Late Holocene sea ice conditions in Herald Canyon, Chukchi Sea

    Science.gov (United States)

    Pearce, C.; O'Regan, M.; Rattray, J. E.; Hutchinson, D. K.; Cronin, T. M.; Gemery, L.; Barrientos, N.; Coxall, H.; Smittenberg, R.; Semiletov, I. P.; Jakobsson, M.

    2017-12-01

    Sea ice in the Arctic Ocean has been in steady decline in recent decades and, based on satellite data, the retreat is most pronounced in the Chukchi and Beaufort seas. Historical observations suggest that the recent changes were unprecedented during the last 150 years, but for a longer time perspective, we rely on the geological record. For this study, we analyzed sediment samples from two piston cores from Herald Canyon in the Chukchi Sea, collected during the 2014 SWERUS-C3 Arctic Ocean Expedition. The Herald Canyon is a local depression across the Chukchi Shelf, and acts as one of the main pathways for Pacific Water to the Arctic Ocean after entering through the narrow and shallow Bering Strait. The study site lies at the modern-day seasonal sea ice minimum edge, and is thus an ideal location for the reconstruction of past sea ice variability. Both sediment cores contain late Holocene deposits characterized by high sediment accumulation rates (100-300 cm/kyr). Core 2-PC1 from the shallow canyon flank (57 m water depth) is 8 meter long and extends back to 4200 cal yrs BP, while the upper 3 meters of Core 4-PC1 from the central canyon (120 mwd) cover the last 3000 years. The chronologies of the cores are based on radiocarbon dates and the 3.6 ka Aniakchak CFE II tephra, which is used as an absolute age marker to calculate the marine radiocarbon reservoir age. Analysis of biomarkers for sea ice and surface water productivity indicate stable sea ice conditions throughout the entire late Holocene, ending with an abrupt increase of phytoplankton sterols in the very top of both sediment sequences. The shift is accompanied by a sudden increase in coarse sediments (> 125 µm) and a minor change in δ13Corg. We interpret this transition in the top sediments as a community turnover in primary producers from sea ice to open water biota. Most importantly, our results indicate that the ongoing rapid ice retreat in the Chukchi Sea of recent decades was unprecedented during the

  12. Deep-sea Hexactinellida (Porifera) of the Weddell Sea

    Science.gov (United States)

    Janussen, Dorte; Tabachnick, Konstantin R.; Tendal, Ole S.

    2004-07-01

    New Hexactinellida from the deep Weddel Sea are described. This moderately diverse hexactinellid fauna includes 14 species belonging to 12 genera, of which five species and one subgenus are new to science: Periphragella antarctica n. sp., Holascus pseudostellatus n. sp., Caulophacus (Caulophacus) discohexactinus n. sp., C. ( Caulodiscus) brandti n. sp., C. ( Oxydiscus) weddelli n. sp., and C. ( Oxydiscus) n. subgen. So far, 20 hexactinellid species have been reported from the deep Weddell Sea, 15 are known from the northern part and 10 only from here, while 10 came from the southern area, and five of these only from there. However, this apparent high "endemism" of Antarctic hexactinellid sponges is most likely the result of severe undersampling of the deep-sea fauna. We find no reason to believe that a division between an oceanic and a more continental group of species exists. The current poor database indicates that a substantial part of the deep hexactinellid fauna of the Weddell Sea is shared with other deep-sea regions, but it does not indicate a special biogeographic relationship with any other ocean.

  13. Numerical modelling of climate change impacts on freshwater lenses on the North Sea Island of Borkum using hydrological and geophysical methods

    Science.gov (United States)

    Sulzbacher, H.; Wiederhold, H.; Siemon, B.; Grinat, M.; Igel, J.; Burschil, T.; Günther, T.; Hinsby, K.

    2012-10-01

    A numerical, density dependent groundwater model is set up for the North Sea Island of Borkum to estimate climate change impacts on coastal aquifers and especially the situation of barrier islands in the Wadden Sea. The database includes information from boreholes, a seismic survey, a helicopter-borne electromagnetic (HEM) survey, monitoring of the freshwater-saltwater boundary by vertical electrode chains in two boreholes, measurements of groundwater table, pumping and slug tests, as well as water samples. Based on a statistical analysis of borehole columns, seismic sections and HEM, a hydrogeological model is set up. The groundwater model is developed using the finite-element programme FEFLOW. The density dependent groundwater model is calibrated on the basis of hydraulic, hydrological and geophysical data, in particular spatial HEM and local monitoring data. Verification runs with the calibrated model show good agreement between measured and computed hydraulic heads. A good agreement is also obtained between measured and computed density or total dissolved solids data for both the entire freshwater lens on a large scale and in the area of the well fields on a small scale. For simulating future changes in this coastal groundwater system until the end of the current century, we use the climate scenario A2, specified by the Intergovernmental Panel on Climate Change and, in particular, the data for the German North Sea coast. Simulation runs show proceeding salinisation with time beneath the well fields of the two waterworks Waterdelle and Ostland. The modelling study shows that the spreading of well fields is an appropriate protection measure against excessive salinisation of the water supply until the end of the current century.

  14. Numerical modelling of climate change impacts on freshwater lenses on the North Sea Island of Borkum using hydrological and geophysical methods

    Directory of Open Access Journals (Sweden)

    H. Sulzbacher

    2012-10-01

    Full Text Available A numerical, density dependent groundwater model is set up for the North Sea Island of Borkum to estimate climate change impacts on coastal aquifers and especially the situation of barrier islands in the Wadden Sea. The database includes information from boreholes, a seismic survey, a helicopter-borne electromagnetic (HEM survey, monitoring of the freshwater-saltwater boundary by vertical electrode chains in two boreholes, measurements of groundwater table, pumping and slug tests, as well as water samples. Based on a statistical analysis of borehole columns, seismic sections and HEM, a hydrogeological model is set up. The groundwater model is developed using the finite-element programme FEFLOW. The density dependent groundwater model is calibrated on the basis of hydraulic, hydrological and geophysical data, in particular spatial HEM and local monitoring data. Verification runs with the calibrated model show good agreement between measured and computed hydraulic heads. A good agreement is also obtained between measured and computed density or total dissolved solids data for both the entire freshwater lens on a large scale and in the area of the well fields on a small scale.

    For simulating future changes in this coastal groundwater system until the end of the current century, we use the climate scenario A2, specified by the Intergovernmental Panel on Climate Change and, in particular, the data for the German North Sea coast. Simulation runs show proceeding salinisation with time beneath the well fields of the two waterworks Waterdelle and Ostland.

    The modelling study shows that the spreading of well fields is an appropriate protection measure against excessive salinisation of the water supply until the end of the current century.

  15. Dermal fibroblast-to-myofibroblast transition sustained by αvß3 integrin-ILK-Snail1/Slug signaling is a common feature for hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders.

    Science.gov (United States)

    Zoppi, Nicoletta; Chiarelli, Nicola; Binetti, Silvia; Ritelli, Marco; Colombi, Marina

    2018-04-01

    Hypermobile Ehlers-Danlos syndrome (hEDS) is a heritable connective tissue disorder with unknown molecular basis mainly characterized by generalized joint hypermobility, joint instability complications, and minor skin changes. The phenotypic spectrum is broad and includes multiple associated symptoms shared with chronic inflammatory systemic diseases. The stricter criteria defined in the 2017 EDS nosology leave without an identity many individuals with symptomatic joint hypermobility and/or features of hEDS; for these patients, the term Hypermobility Spectrum Disorders (HSD) was introduced. We previously reported that in vitro cultured hEDS and HSD patients' skin fibroblasts show a disarray of several extracellular matrix (ECM) components and dysregulated expression of genes involved in connective tissue homeostasis and inflammatory/pain/immune responses. Herein, we report that hEDS and HSD skin fibroblasts exhibit in vitro a similar myofibroblast-like phenotype characterized by the organization of α-smooth muscle actin cytoskeleton, expression of OB-cadherin/cadherin-11, enhanced migratory capability associated with augmented levels of the ECM-degrading metalloproteinase-9, and altered expression of the inflammation mediators CCN1/CYR61 and CCN2/CTGF. We demonstrate that in hEDS and HSD cells this fibroblast-to-myofibroblast transition is triggered by a signal transduction pathway that involves αvβ3 integrin-ILK complexes, organized in focal adhesions, and the Snail1/Slug transcription factor, thus providing insights into the molecular mechanisms related to the pathophysiology of these protean disorders. The indistinguishable phenotype identified in hEDS and HSD cells resembles an inflammatory-like condition, which correlates well with the systemic phenotype of patients, and suggests that these multisystemic disorders might be part of a phenotypic continuum rather than representing distinct clinical entities. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. Climatology of sea breezes along the Red Sea coast of Saudi Arabia

    KAUST Repository

    Khan, Basit

    2018-04-25

    Long-term near-surface observations from five coastal stations, high-resolution model data from Modern Era Retrospective-Analysis for Research and Applications (MERRA) and high-resolution daily sea surface temperature (SST) from National Ocean and Atmospheric Administration (NOAA) are used to investigate the climatology of sea breezes over the eastern side of the Red Sea region. Results show existence of separate sea breeze systems along different segments of the Red Sea coastline. Based on the physical character and synoptic influences, sea breezes in the Red Sea are broadly divided into three regions: the north and the middle Red Sea (NMRS), the Red Sea convergence zone (RSCZ) and the southern Red Sea (SRS) regions. On average, sea breezes developed on 67% of days of the 10-year study period. Although sea breezes occur almost all year, this mesoscale phenomenon is most frequent from May to October (78% of the total sea breeze days). The sea breeze frequency increases from north to south (equatorwards), and sea breeze characteristics appear to vary both temporally and spatially. In addition to land-sea thermal differential, coastline shape, latitude and topography, the prevailing northwesterly at NMRS region, the convergence of northwesterly and southeasterly wind system at RSCZ region and the northeast and southwest monsoon at SRS region play an important role in defining the sea breeze characteristics over the Red Sea.

  17. Integrating out the Dirac sea

    Energy Technology Data Exchange (ETDEWEB)

    Karbstein, Felix

    2009-07-08

    We introduce a new method for dealing with fermionic quantum field theories amenable to a mean-field-type approximation. In this work we focus on the relativistic Hartree approximation. Our aim is to integrate out the Dirac sea and derive a no-sea effective theory'' with positive energy single particle states only. As the derivation of the no-sea effective theory involves only standard Feynman diagrams, our approach is quite general and not restricted to particular space-time dimensions. We develop and illustrate the approach in the ''large N'' limit of the Gross-Neveu model family in 1+1 dimensions. As the Gross-Neveu model has been intensely studied and several analytical solutions are known for this model, it is an ideal testing ground for our no-sea effective theory approach. The chiral Gross-Neveu model, also referred to as 1+1 dimensional Nambu-Jona-Lasinio model, turns out to be of particular interest. In this case, we explicitly derive a consistent effective theory featuring both elementary ''{pi} meson'' fields and (positive energy) ''quark'' fields, starting from a purely fermionic quantum field theory. In the second part of this work, we apply our approach to the Walecka model in 1+1 and 3+1 dimensions. As the Dirac sea caused considerable difficulties in attempts to base nuclear physics on field theoretic models like the Walecka model, mean-field calculations were typically done without the sea. We confront several of these mean-field theory results with our no-sea effective theory approach. The potential of our approach is twofold. While the no-sea effective theory can be utilized to provide new analytical insights in particular parameter regimes, it also sheds new light on more fundamental issues as the explicit emergence of effective, Dirac-sea induced multi-fermion interactions in an effective theory with positive energy states only. (orig.)

  18. Atmospheric forcing of sea ice leads in the Beaufort Sea

    Science.gov (United States)

    Lewis, B. J.; Hutchings, J.; Mahoney, A. R.; Shapiro, L. H.

    2016-12-01

    Leads in sea ice play an important role in the polar marine environment where they allow heat and moisture transfer between the oceans and atmosphere and act as travel pathways for both marine mammals and ships. Examining AVHRR thermal imagery of the Beaufort Sea, collected between 1994 and 2010, sea ice leads appear in repeating patterns and locations (Eicken et al 2005). The leads, resolved by AVHRR, are at least 250m wide (Mahoney et al 2012), thus the patterns described are for lead systems that extend up to hundreds of kilometers across the Beaufort Sea. We describe how these patterns are associated with the location of weather systems relative to the coastline. Mean sea level pressure and 10m wind fields from ECMWF ERA-Interim reanalysis are used to identify if particular lead patterns can be uniquely forecast based on the location of weather systems. Ice drift data from the NSIDC's Polar Pathfinder Daily 25km EASE-Grid Sea Ice Motion Vectors indicates the role shear along leads has on the motion of ice in the Beaufort Gyre. Lead formation is driven by 4 main factors: (i) coastal features such as promontories and islands influence the origin of leads by concentrating stresses within the ice pack; (ii) direction of the wind forcing on the ice pack determines the type of fracture, (iii) the location of the anticyclone (or cyclone) center determines the length of the fracture for certain patterns; and (iv) duration of weather conditions affects the width of the ice fracture zones. Movement of the ice pack on the leeward side of leads originating at promontories and islands increases, creating shear zones that control ice transport along the Alaska coast in winter. . Understanding how atmospheric conditions influence the large-scale motion of the ice pack is needed to design models that predict variability of the gyre and export of multi-year ice to lower latitudes.

  19. Checking contamination of the sea

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1972-07-01

    In July, 133 scientists from 15 countries attended an IAEA symposium on the Interaction of Radioactive Contaminants with the Constituents of the Marine Environment. It was held at the University of Washington, with the USAEC acting as host. Representatives from five international organisations, the CEC, OECD-NEA, WFUNA, WHO and the IAEA attended. The symposium was primarily aimed at elucidating the influence of radioactivity on the marine ecosystem and providing some background material for estimation of the capacity of the sea to accept radioactive waste without any significant harmful effects on man and the ecosystem. At the U. N. Conference on Human Environment held in Stockholm in June this year, a special concern was expressed regarding the international waters, such as the seas and oceans, and the need to conserve the resources of the sea. For the past 14 years the Agency has conducted an intensive programme on the discharge of radioactive waste into the sea, and the behaviour of radionuclides in the sea. (author)

  20. Barents Sea Monitoring with a SEA EXPLORER Glider

    OpenAIRE

    Field, Michael; Béguery, Laurent; Oziel, Laurent; Gascard, Jean-Claude

    2015-01-01

    International audience; The use of gliders in the Polar Regions offers clever and inexpensive methods for large scale monitoring and exploration. In August and September of 2014, a SEA EXPLORER glider successfully completed a 388 km mission in the central Barents Sea to monitor the physical and biological features over a transect between 72° 30' N and 74° 30' N latitude and between 32° E and 33° E longitude, as part of the European FP7 ACCESS project and in cooperation with the Institute of M...

  1. Alone by the Sea

    Directory of Open Access Journals (Sweden)

    Zoran Ferić

    2015-06-01

    Full Text Available 1.At first the island is just a sign on a yellow board with a drawing of a vessel and the letters saying “Car Ferry,” then it is a grayish silhouette in the blue of the sea, and then, later still, an acquaintance working on the ferry, who just nods briefly in greeting. Jablanac, ferry port, its pleasant lobby, and then, from the upper deck, a giant rock approaching. That is the object of a year-long desire: the moment of stepping off the boat and smelling the rosemary, diesel and sheep droppings, seeing the sharp rocks looking at the Strait of Senj, coarse limestone in sharp opposition to the signs that say: Benvenuti, Welcome, Willkommen!At home, on the terrace, in the shade of the oleander, there’s no wish to eat. Only swimming trunks are put on and then, barefoot, without a towel or sun-tanning lotion, off to the beach.“Why won’t you eat something?” grandma asks.She knows that there’s an exciting world waiting out there, but she knows nothing of the details. All friends went on a boat trip. And suddenly one step from the shade of a path covered with oleanders and acacias leads into the burning sun of the afternoon. The light screams, just like children in the water, just like white objects that radiate as if there are some powerful light bulbs within. The feeling of freedom of someone who has just arrived in a foreign place and can now do anything. There’s no one familiar on the beach, they all got in the boat and left. The seafront leading to the camp is full of people, naked children with dirty faces licking ice cream, young families pushing strollers, groups of teenagers who have just woken up from their last night’s party. But there’s no one that must be greeted. The feeling of freedom that’s at the same time close to death. Suddenly, all paths are open. That there are no obligations or friends waiting, this afternoon, until they come back, is a complete boon.

  2. On The Black Sea Surozhian

    Science.gov (United States)

    Caraivan, Glicherie; Corneliu, Cerchia

    2016-04-01

    Some Black Sea researchers still support the idea of no other connection to the Mediterranean Sea between LGM and Karangatian Stage (Riss - Wurm). We try to clarify the source of these disagreements. C14 AMS age data (HERAS Project) made on undisturbed samples from a new Mamaia drilling hole where compared with the classical Black Sea stratigraphic schemes. A first transgressive event (Zone D) is found between 38.00 - 20.20 m depth. Zone D4 shows a fairly rapid rise of sea level, about 10 m below the present one indicating an inner shelf marine polyhaline environment. AMS age data show 14C ages between 53690 - 47359 y (MIS 1), corresponding to the "Surozhian Beds" of Popov. The "beach rock" from Zone E marks the decrease of the sea level after the maximum reached in Zone D4. Zone E mollusc shells AMS data, indicate 14C ages of 48724 - 44604 y, suggesting a long-time reworked material from the previous D4 zone sediments, and represents the beginning of the "regressive Tarkankutian" sequence.The Last Glacial Maximum (LGM) led to the retreat of the sea level down to about 100 m below the current one (27-17 ky BP), followed by an retreat of the shoreline to the present position. At the beginning of the Holocene - MIS 1 (8408-8132 cal. y BP), Black Sea brackish water level grew rapidly, up to -14 m below the present one (Zone F: 22, 57-20, 20 m). Zone F deposits could be correlated with the Bugazian strata. Then, a continuous rising of the Black Sea level is recorded up to a maximum of -2 m under the present one, about 6789 - 7063 cal. y BP, when a transgressive spurt ("Neolithic transgression") may have taken place. After that, given a weak Danubian sedimentary input, coastal erosion intensified. The coarse sandy sediments were reworked and pushed over the previous peat deposits, and suggest a classical "sedimentary regression", not a sea-level decrease. During the last 1.5 ky, sea level has risen towards the current one. Previous C14 dates from "Karangatian

  3. Vulnerability of marginal seas to sea level rise

    Science.gov (United States)

    Gomis, Damia; Jordà, Gabriel

    2017-04-01

    Sea level rise (SLR) is a serious thread for coastal areas and has a potential negative impact on society and economy. SLR can lead for instance to land loss, beach reduction, increase of the damage of marine storms on coastal infrastructures and to the salinization of underground water streams. It is well acknowledged that future SLR will be inhomogeneous across the globe, with regional differences of up to 100% with respect to global mean sea level (GMSL). Several studies have addressed the projections of SLR at regional scale, but most of them are based on global climate models (GCMs) that have a relatively coarse spatial resolution (>1°). In marginal seas this has proven to be a strong limitation, as their particular configurations require spatial resolutions that are not reachable by present GCMs. A paradigmatic case is the Mediterranean Sea, connected to the global ocean through the Strait of Gibraltar, a narrow passage of 14 km width. The functioning of the Mediterranean Sea involves a variety of processes including an overturning circulation, small-scale convection and a rich mesoscale field. Moreover, the long-term evolution of Mediterranean sea level has been significantly different from the global mean during the last decades. The observations of present climate and the projections for the next decades have lead some authors to hypothesize that the particular characteristics of the basin could allow Mediterranean mean sea level to evolve differently from the global mean. Assessing this point is essential to undertake proper adaptation strategies for the largely populated Mediterranean coastal areas. In this work we apply a new approach that combines regional and global projections to analyse future SLR. In a first step we focus on the quantification of the expected departures of future Mediterranean sea level from GMSL evolution and on the contribution of different processes to these departures. As a result we find that, in spite of its particularities

  4. Sea ice dynamics across the Mid-Pleistocene transition in the Bering Sea.

    Science.gov (United States)

    Detlef, H; Belt, S T; Sosdian, S M; Smik, L; Lear, C H; Hall, I R; Cabedo-Sanz, P; Husum, K; Kender, S

    2018-03-05

    Sea ice and associated feedback mechanisms play an important role for both long- and short-term climate change. Our ability to predict future sea ice extent, however, hinges on a greater understanding of past sea ice dynamics. Here we investigate sea ice changes in the eastern Bering Sea prior to, across, and after the Mid-Pleistocene transition (MPT). The sea ice record, based on the Arctic sea ice biomarker IP 25 and related open water proxies from the International Ocean Discovery Program Site U1343, shows a substantial increase in sea ice extent across the MPT. The occurrence of late-glacial/deglacial sea ice maxima are consistent with sea ice/land ice hysteresis and land-glacier retreat via the temperature-precipitation feedback. We also identify interactions of sea ice with phytoplankton growth and ocean circulation patterns, which have important implications for glacial North Pacific Intermediate Water formation and potentially North Pacific abyssal carbon storage.

  5. Oil and the Caspian Sea

    International Nuclear Information System (INIS)

    Mohammad Poure Daryaei, N.

    2000-01-01

    Caspian Sea is the biggest lake in the world. It is almost F-shape and located between five Countries of Iran, Turkmenistan, Russia, Azarbayjohn, Ghazaghestan. Un fortunately, in the different region of the sea there are highly contaminated oil, in addition with other source of pollutants such as: agricultural, industrial and domestic pollution, which causes to eliminate the natural habitats of aquatic life and thus, the Caspian sea with all of the valuable natural sources of foods and energy is close to be destroyed. This paper studies the pollution by oil industry which causes the elimination of aquatic life and natural ecosystem, as well as, necessary plan to over come the present situation

  6. GHRSST Level 4 DMI_OI North Sea and Baltic Sea Regional Foundation Sea Surface Temperature Analysis (GDS version 1)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A Group for High Resolution Sea Surface Temperature (GHRSST) Level 4 sea surface temperature analysis produced daily on an operational basis by the Danish...

  7. The Alkali/Surfactant/ Polymer Process: Effects of Slug Size, Core Length and a Chase Polymer Le procédé alkali/surfactant/polymère : effets de la taille du bouchon, de la longueur de la carotte et d'un polymère de déplacement

    Directory of Open Access Journals (Sweden)

    Green K. A.

    2006-11-01

    Full Text Available An experimental study was conducted to examine the effects of slug size, core length, and a chase polymer on the effectiveness of the alkali/surfactant/polymer (A/S/P process in recovering waterflood residual oil. Core flood experiments were conducted with unfired linear Berea sandstone cores. The tertiary oil recovery, oil cut, pressure drop, and chemical propagation were measured for each flood. Tertiary oil recovery significantly increased with the slug size up to 0. 5 of a pore volume. Increasing the slug size further resulted in a smaller incremental increase in oil recovery. A slight increase in tertiary oil recovery was obtained when small size A/S/P slugs were followed with achase polymer having a viscosity higher than the slug. The lack of oil recovery with small A/S/P slugs was due to the consumption and dilution of the injected chemicals, especially the synthetic surfactant, due to adsorption and dispersion. Increasing the core length by a factor of 4. 5 (from 9 to 40. 6 cm had no significant effect on tertiary oil recovery. Chemical propagation was found to be a function of core length (i. e. , core Peclet number and the size of the chase polymer slug. Increasing core length and employing a chase polymer maintained the integrity of the A/S/P slug by decreasing the effect of dispersion and minimizing the influence of viscous fingering at the tail of the A/S/P slug. Une étude expérimentale a été effectuée pour examiner les effets de la taille du bouchon, de la longueur de la carotte et de l'emploi d'un polymère de déplacement sur l'efficacité du procédé A/S/P (alkali/surfactant/polymère dans la récupération d'huile résiduelle par injection d'eau. Les expériences d'injection ont été faites avec des carottes rectilignes en grès de Berea vert. La récupération tertiaire du pétrole, la présence d'eau, la perte de charge et la propagation chimique ont été mesurées pour chaque injection. La récupération tertiaire du

  8. 16 MW under the seas

    International Nuclear Information System (INIS)

    Mary, Olivier

    2014-01-01

    This article presents the Nemo project (Nemo stands for New Energy for Martinique and Overseas) and its precursor project, Ner 300, developed in cooperation between Akuo Energy and DCNS, and which is financed by the European Bank for Investment. These projects aim at exploiting sea thermal energy. Ner 300 will exploit the 20 degree difference between surface waters (25 C) and deep waters (5 C at 1.000 m under sea level). The article evokes works performed by DCNS to develop a prototype near the Reunion Island. The principle and operation are briefly described, and technological challenges are outlined

  9. How SEA can inform lenders

    DEFF Research Database (Denmark)

    Banhalmi-Zakar, Zsuzsa; Larsen, Sanne Vammen

    with identifying the financial incentives that ‘green’ projects attract. Although bank lending decisions apply to projects, examination of the lending practices of an Australian and a Hungarian bank have shown that decisions about the type of projects to target or avoid are also made at strategic level...... to inform bank lending decisions.......SEA can be a powerful tool to improve decision-making for plans, policies and programmes, but it can also be a useful for banks. SEA can help lenders address the reputational risks they are exposed to through financing projects that may have a negative impact on the environment and it can also help...

  10. North Sea oil directory 1976

    Energy Technology Data Exchange (ETDEWEB)

    1976-01-01

    This edition of the North Sea Oil Directory has been revised to keep pace with the ever-changing North Sea industry. The information is grouped under the following topics: exploration and production; group licensees; Dutch and Norwegian licensees; UK Offshore Operators Association Committees; drilling contractors; offshore exploration and surveys; cement, drilling fluids, and related equipment; drilling equipment; prime mover, transmission equipment; production and process equipment; rig and platform equipment suppliers; rig builders, ship builders; rig and platform logistics; ports, supply bases; marine civil engineering; specialized equipment and services; classified index; and an alphabetical index. (MCW)

  11. Black Sea coastal forecasting system

    Directory of Open Access Journals (Sweden)

    A. I. Kubryakov

    2012-03-01

    Full Text Available The Black Sea coastal nowcasting and forecasting system was built within the framework of EU FP6 ECOOP (European COastalshelf sea OPerational observing and forecasting system project for five regions: the south-western basin along the coasts of Bulgaria and Turkey, the north-western shelf along the Romanian and Ukrainian coasts, coastal zone around of the Crimea peninsula, the north-eastern Russian coastal zone and the coastal zone of Georgia. The system operates in the real-time mode during the ECOOP project and afterwards. The forecasts include temperature, salinity and current velocity fields. Ecosystem model operates in the off-line mode near the Crimea coast.

  12. The watch on the sea

    International Nuclear Information System (INIS)

    1967-01-01

    The film introduces the International Atomic Energy Agency's Laboratory of Marine Radioactivity in Monaco. Established to conduct a special programme of research, the Monaco Laboratory is maintained through the cooperation of the Monaco and the French authorities and with the participation of the United Nations Educational, Scientific and Cultural Organization (UNESCO). The work of the Laboratory in surveying the radioactivity in seawater as well as the rate of absorption of radioactivity in the sea bed is described. Also shown is the laboratory's ship 'Winaretta Singer' as it trawls for specimens of sea life from the seabed and the method by which it obtains samples of seawater at various depths

  13. Is sea-level rising?

    Digital Repository Service at National Institute of Oceanography (India)

    Unnikrishnan, A.S.

    correction in the estimation of trends obtained for tide gauge records. The altimeter data permits to prepare spatial maps of sea-level rise trends. We present a map prepared for the Indian Ocean (Figure 4) north of 10oS , which shows a fairly uniform... drawn information from research papers published by the author and report of the IPCC AR5 WG1 Chapter 13: Sea Level Changes, in which the author has served as a ‘Lead Author’. Figure1 is prepared using data from the University of Colorado. Nerem, R...

  14. The watch on the sea

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1968-12-31

    The film introduces the International Atomic Energy Agency`s Laboratory of Marine Radioactivity in Monaco. Established to conduct a special programme of research, the Monaco Laboratory is maintained through the cooperation of the Monaco and the French authorities and with the participation of the United Nations Educational, Scientific and Cultural Organization (UNESCO). The work of the Laboratory in surveying the radioactivity in seawater as well as the rate of absorption of radioactivity in the sea bed is described. Also shown is the laboratory`s ship `Winaretta Singer` as it trawls for specimens of sea life from the seabed and the method by which it obtains samples of seawater at various depths

  15. Sea Turtle Research Program Summary Report

    National Research Council Canada - National Science Library

    1997-01-01

    The USACE Sea Turtle Research Program (STRP) was conducted to minimize the risk to sea turtle populations in channels along the southeast Atlantic region of the United States from hopper-dredging activities...

  16. Primary production in the Sulu Sea

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    its remotely sensed values from OCTS (Ocean Colour Temperature Scanner) are found to be in ... Although the Sulu Sea is more productive than the adjacent South China Sea, the central area ... surrounding ocean by a chain of islands.

  17. Sea turtles sightings in North Carolina

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sea turtles sightings are reported to the NMFS Beaufort Laboratory sea turtle program by the general public as they are fishing, boating, etc. These sightings...

  18. Comparative metagenomics of the Red Sea

    KAUST Repository

    Mineta, Katsuhiko

    2016-01-01

    started monthly samplings of the metagenomes in the Red Sea under KAUST-CCF project. In collaboration with Kitasato University, we also collected the metagenome data from the ocean in Japan, which shows contrasting features to the Red Sea. Therefore

  19. 2010 USGS Lidar: Salton Sea (CA)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The USGS Salton Sea project encompasses a 5-kilometer buffer around the Salton Sea, California. Dewberry classified LiDAR for a project boundary that touches 623...

  20. Nutrient Limitation in Central Red Sea Mangroves

    KAUST Repository

    Almahasheer, Hanan; Duarte, Carlos M.; Irigoien, Xabier

    2016-01-01

    Red Sea have characteristic heights of ~2 m, suggesting nutrient limitation. We assessed the nutrient status of mangrove stands in the Central Red Sea and conducted a fertilization experiment (N, P and Fe and various combinations thereof) on 4-week

  1. Extended Reconstructed Sea Surface Temperature (ERSST)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Extended Reconstructed Sea Surface Temperature (ERSST) dataset is a global monthly sea surface temperature analysis derived from the International Comprehensive...

  2. Quarterly Fishery Surveys - Salton Sea [ds428

    Data.gov (United States)

    California Natural Resource Agency — In the spring of 2003, California Department of Fish and Game (CDFG) personnel began quarterly sampling of Salton Sea fish at fourteen stations around the sea, as...

  3. Arctic Sea Ice Freeboard and Thickness

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set provides measurements of sea ice freeboard and sea ice thickness for the Arctic region. The data were derived from measurements made by from the Ice,...

  4. Temperature, salinity, and nutrients data collected from North Atlantic Ocean, White Sea, Mediterranean Sea, Black Sea, and Sea of Azov from 1924-03-19 to 1989-11-19 by multiple Soviet Union institutes (NODC Accession 0077413)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature, salinity, and nutrients data collected from North Atlantic Ocean, White Sea, Mediterranean Sea, Black Sea, and Sea of Azov from 1924-03-19 to 1989-11-19...

  5. Modelling the extinction of Steller's sea cow

    OpenAIRE

    Turvey, S.T; Risley, C.L

    2005-01-01

    Steller's sea cow, a giant sirenian discovered in 1741 and extinct by 1768, is one of the few megafaunal mammal species to have died out during the historical period. The species is traditionally considered to have been exterminated by ‘blitzkrieg’-style direct overharvesting for food, but it has also been proposed that its extinction resulted from a sea urchin population explosion triggered by extirpation of local sea otter populations that eliminated the shallow-water kelps on which sea cow...

  6. Autonomous Sea-Ice Thickness Survey

    Science.gov (United States)

    2016-06-01

    the conductivity of an infinitely thick slab of sea ice. Ice thickness, Hice, is then obtained by subtracting the height of the ...Thickness Survey of Sea Ice Runway” ERDC/CRREL SR-16-4 ii Abstract We conducted an autonomous survey of sea -ice thickness using the Polar rover Yeti...efficiency relative to manual surveys routinely con- ducted to assess the safety of roads and runways constructed on the sea ice. Yeti executed the

  7. Climatology of sea breezes along the Red Sea coast of Saudi Arabia

    KAUST Repository

    Khan, Basit; Abualnaja, Yasser; Al-Subhi, Abdullah M.; Nellayaputhenpeedika, Mohammedali; Nellikkattu Thody, Manoj; Sturman, Andrew P.

    2018-01-01

    and Atmospheric Administration (NOAA) are used to investigate the climatology of sea breezes over the eastern side of the Red Sea region. Results show existence of separate sea breeze systems along different segments of the Red Sea coastline. Based on the physical

  8. Sea Surface Height Variability and Eddy Statistical Properties in the Red Sea

    KAUST Repository

    Zhan, Peng

    2013-01-01

    Satellite sea surface height (SSH) data over 1992-2012 are analyzed to study the spatial and temporal variability of sea level in the Red Sea. Empirical orthogonal functions (EOF) analysis suggests the remarkable seasonality of SSH in the Red Sea

  9. Monitoring sea level and sea surface temperature trends from ERS satellites

    DEFF Research Database (Denmark)

    Andersen, Ole Baltazar; Knudsen, Per; Beckley, B.

    2002-01-01

    Data from the two ESA satellites ERS-1 and ERS-2 are used in global and regional analysis of sea level and sea surface temperature trends over the last, 7.8 years. T he ERS satellites and in the future the ENVISAT satellite provide unique opportunity for monitoring both changes in sea level and sea...

  10. Global sea turtle conservation successes.

    Science.gov (United States)

    Mazaris, Antonios D; Schofield, Gail; Gkazinou, Chrysoula; Almpanidou, Vasiliki; Hays, Graeme C

    2017-09-01

    We document a tendency for published estimates of population size in sea turtles to be increasing rather than decreasing across the globe. To examine the population status of the seven species of sea turtle globally, we obtained 299 time series of annual nesting abundance with a total of 4417 annual estimates. The time series ranged in length from 6 to 47 years (mean, 16.2 years). When levels of abundance were summed within regional management units (RMUs) for each species, there were upward trends in 12 RMUs versus downward trends in 5 RMUs. This prevalence of more upward than downward trends was also evident in the individual time series, where we found 95 significant increases in abundance and 35 significant decreases. Adding to this encouraging news for sea turtle conservation, we show that even small sea turtle populations have the capacity to recover, that is, Allee effects appear unimportant. Positive trends in abundance are likely linked to the effective protection of eggs and nesting females, as well as reduced bycatch. However, conservation concerns remain, such as the decline in leatherback turtles in the Eastern and Western Pacific. Furthermore, we also show that, often, time series are too short to identify trends in abundance. Our findings highlight the importance of continued conservation and monitoring efforts that underpin this global conservation success story.

  11. Ploughing the deep sea floor.

    Science.gov (United States)

    Puig, Pere; Canals, Miquel; Company, Joan B; Martín, Jacobo; Amblas, David; Lastras, Galderic; Palanques, Albert

    2012-09-13

    Bottom trawling is a non-selective commercial fishing technique whereby heavy nets and gear are pulled along the sea floor. The direct impact of this technique on fish populations and benthic communities has received much attention, but trawling can also modify the physical properties of seafloor sediments, water–sediment chemical exchanges and sediment fluxes. Most of the studies addressing the physical disturbances of trawl gear on the seabed have been undertaken in coastal and shelf environments, however, where the capacity of trawling to modify the seafloor morphology coexists with high-energy natural processes driving sediment erosion, transport and deposition. Here we show that on upper continental slopes, the reworking of the deep sea floor by trawling gradually modifies the shape of the submarine landscape over large spatial scales. We found that trawling-induced sediment displacement and removal from fishing grounds causes the morphology of the deep sea floor to become smoother over time, reducing its original complexity as shown by high-resolution seafloor relief maps. Our results suggest that in recent decades, following the industrialization of fishing fleets, bottom trawling has become an important driver of deep seascape evolution. Given the global dimension of this type of fishery, we anticipate that the morphology of the upper continental slope in many parts of the world’s oceans could be altered by intensive bottom trawling, producing comparable effects on the deep sea floor to those generated by agricultural ploughing on land.

  12. The politics of SEA indicators

    DEFF Research Database (Denmark)

    Gao, Jingjing; Kørnøv, Lone; Christensen, Per

    2013-01-01

    The use of indicators is not only technical and science-led, but also a value-laden social process, and thus concerns public participation, political judgment and decision-making. This article approaches the Chinese SEA indicator system from a science-policy interface and aims at: 1) contributing...

  13. Internal Waves, South China Sea

    Science.gov (United States)

    1983-01-01

    Subsurface ocean currents, frequently referred to as internal waves, are frequently seen from space under the right lighting conditions when depth penetration can be achieved. These internal waves observed in the South China Sea off the SE coast of the island of Hainan (18.5N, 110.5E) visibly demonstrate turbidity in the ocean's depths at the confluence of conflicting currents.

  14. Killer storms from the seas

    Digital Repository Service at National Institute of Oceanography (India)

    Varkey, M.J.

    The author has discussed the distruction taking place due to cyclone in the Indian subcontinent of formation which is said to be the result of thermal fronts in the atmosphere and sea interaction of different air masses is discussed in detailed...

  15. Climate change challenges for SEA

    DEFF Research Database (Denmark)

    Larsen, Sanne Vammen

    This paper takes a theoretical perspective on the challenges that climate changes pose for SEA. The theoretical framework used is the sociologist Ulrich Beck’s theory of risk society and the aspects that characterise this society. Climate change is viewed as a risk, and the theory is used to derive...

  16. Meiofauna of the Andaman Sea

    Digital Repository Service at National Institute of Oceanography (India)

    Ansari, Z.A.; Parulekar, A.H.

    Total meiofauna of the Andaman Sea, in the depth range 30-2150m was between 68 and 438/10cm2 (X-bar = 247.8). The biomass was within the range 3.57 and 32.8mg/10cm 2 (X-bar = 14.46). faunal components were maximum in sandy sediments which contained...

  17. IAHR List of Sea Parameters

    DEFF Research Database (Denmark)

    Frigaard, Peter; Helm-Petersen, J; Klopman, G.

    1997-01-01

    A Working Group on multidirectional waves formed by the International Association for Hydraulic Research has proposed an update of the IAHR List of Sea State Parameters from 1986 in the part concerning directional. Especially wave structure interaction with reflection of the waves have been treated....

  18. A Deep-Sea Simulation.

    Science.gov (United States)

    Montes, Georgia E.

    1997-01-01

    Describes an activity that simulates exploration techniques used in deep-sea explorations and teaches students how this technology can be used to take a closer look inside volcanoes, inspect hazardous waste sites such as nuclear reactors, and explore other environments dangerous to humans. (DDR)

  19. Salton Sea Ecosystem Monitoring Project

    Science.gov (United States)

    Miles, A. Keith; Ricca, Mark A.; Meckstroth, Anne; Spring, Sarah E.

    2009-01-01

    The Salton Sea is critically important for wintering and breeding waterbirds, but faces an uncertain future due to water delivery reductions imposed by the Interstate and Federal Quantification Settlement Agreement of 2003. The current preferred alternative for wetland restoration at the Salton Sea is saline habitat impoundments created to mitigate the anticipated loss of wetland habitat. In 2006, a 50-hectare experimental complex that consisted of four inter-connected, shallow water saline habitat ponds (SHP) was constructed at the southeastern shoreline of the Salton Sea and flooded with blended waters from the Alamo River and Salton Sea. The present study evaluated ecological risks and benefits of the SHP concept prior to widespread restoration actions. This study was designed to evaluate (1) baseline chemical, nutrient, and contaminant measures from physical and biological constituents, (2) aquatic invertebrate community structure and colonization patterns, and (3) productivity of and contaminant risks to nesting waterbirds at the SHP. These factors were evaluated and compared with those of nearby waterbird habitat, that is, reference sites.

  20. [Multiple scattering of visible and infrared light by sea fog over wind driving rough sea surface].

    Science.gov (United States)

    Sun, Xian-Ming; Wang, Hai-Hua; Lei, Cheng-Xin; Shen, Jin

    2013-08-01

    The present paper is concerned with computing the multiple scattering characteristics of a sea fog-sea surface couple system within this context. The single scattering characteristics of sea fog were studied by Mie theory, and the multiple scattering of sunlight by single sea fog layer was studied by radiative transfer theory. The reflection function of a statistically rough ocean surface was obtained using the standard Kirchhoff formulation, with shadowing effects taken into account. The reflection properties of the combined sea fog and ocean surface were obtained employing the adding method, and the results indicated that the reflected light intensity of sea fog increased with the sea background.

  1. 50 CFR 223.205 - Sea turtles.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Sea turtles. 223.205 Section 223.205... Threatened Marine and Anadromous Species § 223.205 Sea turtles. (a) The prohibitions of section 9 of the Act (16 U.S.C. 1538) relating to endangered species apply to threatened species of sea turtle, except as...

  2. Parasites in the Wadden Sea food web

    NARCIS (Netherlands)

    Thieltges, D.W.; Engelsma, M.Y.; Wendling, C.C.; Wegner, K.M.

    2013-01-01

    While the free-living fauna of the Wadden Sea has received much interest, little is known on the distribution and effects of parasites in the Wadden Sea food web. However, recent studies on this special type of trophic interaction indicate a high diversity of parasites in the Wadden Sea and suggest

  3. OW NASA SeaWIFS Ocean Color

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The dataset contains satellite-derived sea-surface ocean color (chlorophyll-a) measurements collected by means of the Sea-viewing Wide Field-of-view Sensor (SeaWiFS)...

  4. Vision in the deep sea.

    Science.gov (United States)

    Warrant, Eric J; Locket, N Adam

    2004-08-01

    The deep sea is the largest habitat on earth. Its three great faunal environments--the twilight mesopelagic zone, the dark bathypelagic zone and the vast flat expanses of the benthic habitat--are home to a rich fauna of vertebrates and invertebrates. In the mesopelagic zone (150-1000 m), the down-welling daylight creates an extended scene that becomes increasingly dimmer and bluer with depth. The available daylight also originates increasingly from vertically above, and bioluminescent point-source flashes, well contrasted against the dim background daylight, become increasingly visible. In the bathypelagic zone below 1000 m no daylight remains, and the scene becomes entirely dominated by point-like bioluminescence. This changing nature of visual scenes with depth--from extended source to point source--has had a profound effect on the designs of deep-sea eyes, both optically and neurally, a fact that until recently was not fully appreciated. Recent measurements of the sensitivity and spatial resolution of deep-sea eyes--particularly from the camera eyes of fishes and cephalopods and the compound eyes of crustaceans--reveal that ocular designs are well matched to the nature of the visual scene at any given depth. This match between eye design and visual scene is the subject of this review. The greatest variation in eye design is found in the mesopelagic zone, where dim down-welling daylight and bio-luminescent point sources may be visible simultaneously. Some mesopelagic eyes rely on spatial and temporal summation to increase sensitivity to a dim extended scene, while others sacrifice this sensitivity to localise pinpoints of bright bioluminescence. Yet other eyes have retinal regions separately specialised for each type of light. In the bathypelagic zone, eyes generally get smaller and therefore less sensitive to point sources with increasing depth. In fishes, this insensitivity, combined with surprisingly high spatial resolution, is very well adapted to the

  5. Thermal biology of sea snakes and sea kraits.

    Science.gov (United States)

    Heatwole, Harold; Grech, Alana; Monahan, John F; King, Susan; Marsh, Helene

    2012-08-01

    Temperature probably had no direct effect on the evolution of sea kraits within their center of origin, a geologically stable thermal zone straddling the equator, but may have indirectly affected expansions and contractions in distributions beyond that zone through global fluctuations that caused alternation of higher and lower sea levels. The northern limit of the Laticauda colubrina complex seems to be the 20°C isotherm; in the south, the range does not reach that isotherm because there is no land (also a habitat requirement of sea kraits) within the zone of suitable temperature. The relationship of temperature to the pattern of geographic variation in morphology supports either the hypothesis of peripheral convergence or the developmental hypothesis but does not distinguish between them. Quadratic surfaces relating cumulative scores for coloration and morphological characters to global position showed a strong latitudinal component and an even stronger longitudinal one in which the direction of the latitudinal effect was reversed between east and west. A multivariate analysis revealed that while morphological characters vary significantly by location and climate when tested separately, when the influence of location on morphology is taken into account, no residual relationship between climate and morphology remains. Most marine snakes have mean upper temperature tolerances between 39°C and 40°C and operate at temperatures much nearer their upper thermal limits than their lower limits but still avoid deleterious extremes by diving from excessively hot water to deeper, cooler strata, and by surfacing when water is cold. At the surface in still water in sunlight, Pelamis can maintain its body temperature slightly above that of the water, but whether this is significant in nature is questionable. As temperature falls below 18-20°C, survival time is progressively reduced, accompanied by the successive occurrence of cessation of feeding, cessation of swimming, and

  6. Situation in the sea area between the North Sea and the Baltic Sea. Situationen i havsomraadet mellan Nordsjoen och Oestersjoen

    Energy Technology Data Exchange (ETDEWEB)

    Dybern, B.I.; Soederstroem, J.; Thorell, L.

    1984-01-01

    Due to the special topographical and hydrological features the seas surrounding Sweden are very sensitive to both natural changes and changes caused by man. The sea area between the North Sea and the Baltic Sea has come into focus during the last few decades due to problems with pollution and its impact on the ecosystems and to overfishing of some commer- cially important species. In order to elucidate the present situation from the Swedish viewpoint, the National Board of Fisheries, the National Environment Protection Board and the County Council of the County Goeteborg and Bohyslaen arranged a Symposium on the Situation in the Sea Area between the North Sea and the Baltic Sea in Goeteborg, 14-16 March, 1983. This volume contains lectures given at that Symposium. In most cases there are English summaries and English translations of texts to figures and tables.

  7. Temperature, Salinity, Oxygen, Phosphate, pH and Alkalinity data collected in the North Atlantic Ocean, Baltic Sea, Barents Sea, Greenland Sea, North Sea, Norwegian Sea and White Sea from R/Vs Artemovsk, Atlantida, Okeanograf, Professor Rudovits, and ice observations, 1957 - 1995 (NODC Accession 0073674)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature, Salinity, Oxygen, Phosphate, pH and Alkalinity data collected in the North Atlantic Ocean, Baltic Sea, Barents Sea, Greenland Sea, North Sea, Norwegian...

  8. A scattering approach to sea wave diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Corradini, M. L., E-mail: letizia.corradini@unicam.it; Garbuglia, M., E-mail: milena.garbuglia@unicam.it; Maponi, P., E-mail: pierluigi.maponi@unicam.it [University of Camerino, via Madonna delle Carceri, 9, 62032, Camerino (Italy); Ruggeri, M., E-mail: ru.marco@faggiolatipumps.it [Faggiolati Pumps S.p.A., Z.Ind Sforzacosta, 62100, Macerata (Italy)

    2016-06-08

    This paper intends to show a model for the diffraction of sea waves approaching an OWC device, which converts the sea waves motion into mechanical energy and then electrical energy. This is a preliminary study to the optimisation of the device, in fact the computation of sea waves diffraction around the device allows the estimation of the sea waves energy which enters into the device. The computation of the diffraction phenomenon is the result of a sea waves scattering problem, solved with an integral equation method.

  9. Deglacial sea level history of the East Siberian Sea and Chukchi Sea margins

    Science.gov (United States)

    Cronin, Thomas M.; O'Regan, Matt; Pearce, Christof; Gemery, Laura; Toomey, Michael; Semiletov, Igor

    2017-01-01

    Deglacial (12.8–10.7 ka) sea level history on the East Siberian continental shelf and upper continental slope was reconstructed using new geophysical records and sediment cores taken during Leg 2 of the 2014 SWERUS-C3 expedition. The focus of this study is two cores from Herald Canyon, piston core SWERUS-L2-4-PC1 (4-PC1) and multicore SWERUS-L2-4-MC1 (4-MC1), and a gravity core from an East Siberian Sea transect, SWERUS-L2-20-GC1 (20-GC1). Cores 4-PC1 and 20-GC were taken at 120 and 115 m of modern water depth, respectively, only a few meters above the global last glacial maximum (LGM;  ∼  24 kiloannum or ka) minimum sea level of  ∼  125–130 meters below sea level (m b.s.l.). Using calibrated radiocarbon ages mainly on molluscs for chronology and the ecology of benthic foraminifera and ostracode species to estimate paleodepths, the data reveal a dominance of river-proximal species during the early part of the Younger Dryas event (YD, Greenland Stadial GS-1) followed by a rise in river-intermediate species in the late Younger Dryas or the early Holocene (Preboreal) period. A rapid relative sea level rise beginning at roughly 11.4 to 10.8 ka ( ∼  400 cm of core depth) is indicated by a sharp faunal change and unconformity or condensed zone of sedimentation. Regional sea level at this time was about 108 m b.s.l. at the 4-PC1 site and 102 m b.s.l. at 20-GC1. Regional sea level near the end of the YD was up to 42–47 m lower than predicted by geophysical models corrected for glacio-isostatic adjustment. This discrepancy could be explained by delayed isostatic adjustment caused by a greater volume and/or geographical extent of glacial-age land ice and/or ice shelves in the western Arctic Ocean and adjacent Siberian land areas.

  10. Deglacial sea level history of the East Siberian Sea and Chukchi Sea margins

    Directory of Open Access Journals (Sweden)

    T. M. Cronin

    2017-09-01

    Full Text Available Deglacial (12.8–10.7 ka sea level history on the East Siberian continental shelf and upper continental slope was reconstructed using new geophysical records and sediment cores taken during Leg 2 of the 2014 SWERUS-C3 expedition. The focus of this study is two cores from Herald Canyon, piston core SWERUS-L2-4-PC1 (4-PC1 and multicore SWERUS-L2-4-MC1 (4-MC1, and a gravity core from an East Siberian Sea transect, SWERUS-L2-20-GC1 (20-GC1. Cores 4-PC1 and 20-GC were taken at 120 and 115 m of modern water depth, respectively, only a few meters above the global last glacial maximum (LGM;  ∼  24 kiloannum or ka minimum sea level of  ∼  125–130 meters below sea level (m b.s.l.. Using calibrated radiocarbon ages mainly on molluscs for chronology and the ecology of benthic foraminifera and ostracode species to estimate paleodepths, the data reveal a dominance of river-proximal species during the early part of the Younger Dryas event (YD, Greenland Stadial GS-1 followed by a rise in river-intermediate species in the late Younger Dryas or the early Holocene (Preboreal period. A rapid relative sea level rise beginning at roughly 11.4 to 10.8 ka ( ∼  400 cm of core depth is indicated by a sharp faunal change and unconformity or condensed zone of sedimentation. Regional sea level at this time was about 108 m b.s.l. at the 4-PC1 site and 102 m b.s.l. at 20-GC1. Regional sea level near the end of the YD was up to 42–47 m lower than predicted by geophysical models corrected for glacio-isostatic adjustment. This discrepancy could be explained by delayed isostatic adjustment caused by a greater volume and/or geographical extent of glacial-age land ice and/or ice shelves in the western Arctic Ocean and adjacent Siberian land areas.

  11. Deglacial sea level history of the East Siberian Sea and Chukchi Sea margins

    Science.gov (United States)

    Cronin, Thomas M.; O'Regan, Matt; Pearce, Christof; Gemery, Laura; Toomey, Michael; Semiletov, Igor; Jakobsson, Martin

    2017-09-01

    Deglacial (12.8-10.7 ka) sea level history on the East Siberian continental shelf and upper continental slope was reconstructed using new geophysical records and sediment cores taken during Leg 2 of the 2014 SWERUS-C3 expedition. The focus of this study is two cores from Herald Canyon, piston core SWERUS-L2-4-PC1 (4-PC1) and multicore SWERUS-L2-4-MC1 (4-MC1), and a gravity core from an East Siberian Sea transect, SWERUS-L2-20-GC1 (20-GC1). Cores 4-PC1 and 20-GC were taken at 120 and 115 m of modern water depth, respectively, only a few meters above the global last glacial maximum (LGM; ˜ 24 kiloannum or ka) minimum sea level of ˜ 125-130 meters below sea level (m b.s.l.). Using calibrated radiocarbon ages mainly on molluscs for chronology and the ecology of benthic foraminifera and ostracode species to estimate paleodepths, the data reveal a dominance of river-proximal species during the early part of the Younger Dryas event (YD, Greenland Stadial GS-1) followed by a rise in river-intermediate species in the late Younger Dryas or the early Holocene (Preboreal) period. A rapid relative sea level rise beginning at roughly 11.4 to 10.8 ka ( ˜ 400 cm of core depth) is indicated by a sharp faunal change and unconformity or condensed zone of sedimentation. Regional sea level at this time was about 108 m b.s.l. at the 4-PC1 site and 102 m b.s.l. at 20-GC1. Regional sea level near the end of the YD was up to 42-47 m lower than predicted by geophysical models corrected for glacio-isostatic adjustment. This discrepancy could be explained by delayed isostatic adjustment caused by a greater volume and/or geographical extent of glacial-age land ice and/or ice shelves in the western Arctic Ocean and adjacent Siberian land areas.

  12. Black Sea and Caspian Sea, Symposium II, Constanta, Romania

    Science.gov (United States)

    2007-05-01

    Great, the Bronze Horseman . You may have heard me quote this before, but Pushkin in his poem “Th e Bronze Horseman ,” asks rhe- torically “Whither dost...mile down the embankment from the Bronze Horseman in front of the Admiralty Building in Petersburg. It commemorates the Czarist Foreign Minister...need for a coordinated approach to broader political developments in the Black and Caspian Sea regions. Th e December 21, 2006 death of

  13. The distribution and diversity of sea cucumbers in the coral reefs of the South China Sea, Sulu Sea and Sulawesi Sea

    Science.gov (United States)

    Woo, Sau Pinn; Yasin, Zulfigar; Ismail, Siti Hasmah; Tan, Shau Hwai

    2013-11-01

    A study on the distribution and diversity of sea cucumbers in the coral reefs of the South China Sea, Sulu Sea and Sulawesi Sea was carried out in July 2009. The survey was done using wandering transect underwater with SCUBA. Twelve species of sea cucumber were found from four different families and nine genera. The most dominant family was Holothuriidae (five species), followed by Stichopodidae (three species), Synaptidae (three species) and Cucumariidae with only one species. The most dominant species found around the island was Pearsonothuria graffei, which can be found abundantly on substrate of dead corals in a wide range of depth (6-15 m). The Sulawesi Sea showed a higher diversity of sea cucumber with seven different species compared to the South China Sea with only six different species and Sulu Sea with only two species. Ordination by multidimensional scaling of Bray-Curtis similarities clustered the sampling locations to three main clusters with two outgroups. Previous studies done indicated a higher diversity of sea cucumber as compared to this study. This can be indication that the population and diversity of sea cucumbers in the reef is under threat.

  14. Sea Cucumber (Holothuroidea Species of Turkey

    Directory of Open Access Journals (Sweden)

    Mehmet AYDIN

    2016-11-01

    Full Text Available There are nearly 1200 sea cucumber species in the world oceans, while only 37 species from Holothuroidea class lives in the Mediterranean Sea. This preliminary study aims identification sea cucumbers species of the Turkish waters. The sea cucumber samples used in this study were obtained from a series of different studies between the years of 2008 and 2014. Identification of the species are mainly based on the morphometric characteristics while some of species are determined from their calcareous spicules. Eight sea species were identified in this research which are; Holothuria tubulosa, Holothuria polii, Holothuria mammata, Holothuria (Platyperona sanctori, Holothuria forskali, Stichopus regalis, Synaptula reciprocans and Stereoderma kirschbergi. There are limited number of studies in the literature focusing on the identification of the sea cucumber species spread in our seas. Therefore, this study is believed to play an important role in guiding future researches.

  15. Variability and Trends in Sea Ice Extent and Ice Production in the Ross Sea

    Science.gov (United States)

    Comiso, Josefino; Kwok, Ronald; Martin, Seelye; Gordon, Arnold L.

    2011-01-01

    Salt release during sea ice formation in the Ross Sea coastal regions is regarded as a primary forcing for the regional generation of Antarctic Bottom Water. Passive microwave data from November 1978 through 2008 are used to examine the detailed seasonal and interannual characteristics of the sea ice cover of the Ross Sea and the adjacent Bellingshausen and Amundsen seas. For this period the sea ice extent in the Ross Sea shows the greatest increase of all the Antarctic seas. Variability in the ice cover in these regions is linked to changes in the Southern Annular Mode and secondarily to the Antarctic Circumpolar Wave. Over the Ross Sea shelf, analysis of sea ice drift data from 1992 to 2008 yields a positive rate of increase in the net ice export of about 30,000 sq km/yr. For a characteristic ice thickness of 0.6 m, this yields a volume transport of about 20 cu km/yr, which is almost identical, within error bars, to our estimate of the trend in ice production. The increase in brine rejection in the Ross Shelf Polynya associated with the estimated increase with the ice production, however, is not consistent with the reported Ross Sea salinity decrease. The locally generated sea ice enhancement of Ross Sea salinity may be offset by an increase of relatively low salinity of the water advected into the region from the Amundsen Sea, a consequence of increased precipitation and regional glacial ice melt.

  16. Micromechanics of Sea Urchin spines.

    Directory of Open Access Journals (Sweden)

    Naomi Tsafnat

    Full Text Available The endoskeletal structure of the Sea Urchin, Centrostephanus rodgersii, has numerous long spines whose known functions include locomotion, sensing, and protection against predators. These spines have a remarkable internal microstructure and are made of single-crystal calcite. A finite-element model of the spine's unique porous structure, based on micro-computed tomography (microCT and incorporating anisotropic material properties, was developed to study its response to mechanical loading. Simulations show that high stress concentrations occur at certain points in the spine's architecture; brittle cracking would likely initiate in these regions. These analyses demonstrate that the organization of single-crystal calcite in the unique, intricate morphology of the sea urchin spine results in a strong, stiff and lightweight structure that enhances its strength despite the brittleness of its constituent material.

  17. Scaling the Baltic Sea environment

    DEFF Research Database (Denmark)

    Larsen, Henrik Gutzon

    2008-01-01

    of this development, this article suggests that environmental politics critically depend on the delineation of relatively bounded spaces that identify and situate particular environmental concerns as spatial objects for politics. These spaces are not simply determined by ‘nature' or some environmental......The Baltic Sea environment has since the early 1970s passed through several phases of spatial objectification in which the ostensibly well-defined semi-enclosed sea has been framed and reframed as a geographical object for intergovernmental environmental politics. Based on a historical analysis......-scientific logic, but should rather be seen as temporal outcomes of scale framing processes, processes that are accentuated by contemporary conceptions of the environment (or nature) in terms of multi-scalar ecosystems. This has implications for how an environmental concern is perceived and politically addressed....

  18. Generic Hurricane Extreme Seas State

    DEFF Research Database (Denmark)

    Wehmeyer, Christof; Skourup, Jesper; Frigaard, Peter

    2012-01-01

    Extreme sea states, which the IEC 61400-3 (2008) standard requires for the ultimate limit state (ULS) analysis of offshore wind turbines are derived to establish the design basis for the conceptual layout of deep water floating offshore wind turbine foundations in hurricane affected areas....... Especially in the initial phase of floating foundation concept development, site specific metocean data are usually not available. As the areas of interest are furthermore not covered by any design standard, in terms of design sea states, generic and in engineering terms applicable environmental background...... data is required for a type specific conceptual design. ULS conditions for different return periods are developed, which can subsequently be applied in siteindependent analysis and conceptual design. Recordings provided by National Oceanic and Atmospheric Administration (NOAA), of hurricanes along...

  19. Heavy metals in sea turtles

    Energy Technology Data Exchange (ETDEWEB)

    Witkowski, S.A. (Millersville State College, PA); Frazier, J.G.

    1982-07-01

    Bone and barnacle samples from sea turtles (Hepidochelys olivacea) in Ecuador were analyzed for manganese, iron, copper, zinc and lead. Analysis was performed by flame atomic absorption spectroscopy. Results show that zinc and iron levels in bone and barnacles were greater than copper, manganese and lead levels. The significance of the findings is difficult to interpret because so little is known about baseline levels and physiological effects of heavy metals in the animals. (JMT)

  20. Sea sand for reactive barriers

    International Nuclear Information System (INIS)

    Garcia R, G.; Ordonez R, E.; Ordonez R, En.

    2002-01-01

    Some phosphates have the property to suck in radioactive metals in solution, what it is taken in advance to make reactive barriers which are placed in the nuclear waste repositories. In an effort for contributing to the study of this type of materials, it has been obtained the zirconium silicate (ZrSiO 4 ) and the alpha zirconium hydrogen phosphate (Zr(HPO 4 ) 2H 2 O) starting from sea sand in an easy and economic way. (Author)

  1. Growing halophytes floating at sea

    Directory of Open Access Journals (Sweden)

    Ricardo Radulovich

    2017-11-01

    Full Text Available Freshwater shortages are increasingly limiting both irrigated and rainfed agriculture. To expand possibilities for controlled plant production without using land nor freshwater, we cultivated potted halophytes floating at sea that were provided with rain- and seawater. Plantlets of two mangroves (Avicennia germinans and Rhizophora mangle and plants of two herbaceous species, sea purslane (Sesuvium portulacastrum and salt couch grass (Sporobolus virginicus were grown in near-coastal tropical Pacific waters of Costa Rica for 733 days. There were a total of 504 rainless days, including two dry periods of ca. 150 d long each, evidencing prolonged and exclusive reliance on seawater. Pots with a sandy soil mixture and the transplanted plants were placed on low-cost wooden floating rafts with their lower end perforated and immersed for capillary rise of water. Free seawater entry and exit through the bottom from bobbing with waves, which also occasionally added water from the top, effectively controlled soil salinity build-up even during the rainless seasons. Continuous leaching made necessary frequent fertilizer addition. No water deficit symptoms were observed and midday canopy temperature during rainless periods was not significantly different between species or from air temperature. With all-year-round growth, height increase of mangrove plantlets ranged from 208.1 to 401.5 mm yr−1. Fresh biomass production of sea purslane and the grass was 10.9 and 3.0 kg m−2 yr−1 respectively. High yield, edibility and protein content of 10.2% dry weight established sea purslane as a potential crop. While further research is needed, the method evidenced to be a viable plant production option of potentially far-reaching applications.

  2. Alkalinity of the Mediterranean Sea

    OpenAIRE

    Schneider, Anke; Wallace, Douglas W.R.; Körtzinger, Arne

    2007-01-01

    Total alkalinity (AT) was measured during the Meteor 51/2 cruise, crossing the Mediterranean Sea from west to east. AT concentrations were high (∼2600 μmol kg−1) and alkalinity-salinity-correlations had negative intercepts. These results are explained by evaporation coupled with high freshwater AT inputs into coastal areas. Salinity adjustment of AT revealed excess alkalinity throughout the water column compared to mid-basin surface waters. Since Mediterranean waters are supersaturated with r...

  3. Sea Quarks in the Proton

    Directory of Open Access Journals (Sweden)

    Reimer Paul E

    2016-01-01

    Full Text Available The proton is a composite particle in which the binding force is responsible for the majority of its mass. To understand this structure, the distributions and origins of the quark-antiquark pairs produced by the strong force must be measured. The SeaQuest collaboration is using the Drell-Yan process to elucidate antiquark distributions in the proton and to study their modification when the proton is held within a nucleus.

  4. Sedimentation rate in Ariake Sea

    International Nuclear Information System (INIS)

    Momoshima, Noriyuki; Nishio, Souma; Honza, Eiichi

    2004-01-01

    The Ariake Sea is a shallow and almost enclosed sea located in western Kyushu, Japan with an area of about 1,700 km 2 and the deepest up to 30 m at north area. The most inner part of the bay area is very shallow and during low tide big mudflats tideland appears and extends up to several km. The tidal range is the highest in Japan with a maximum of about 6 m. The area is one of Japan's most important area for fishery, with over 40% of the total seaweed production in Japan In the year 2001, due to environmental conditions, the seaweed population decreased substantially with a production drop of about 50%. This was caused by an earlier winter outbreak of red tide that affected the seaweed quality. One proposed cause for this decline might be the land reclamation project in the western part of Ariake Sea, Isahaya Bay. This project started in April 1997 were more than 3,000 ha of the bay where closed by a 7 km long seawall. Contaminated water is regularly discharged from the reservoir inside the dike, which have resulted in changes in water flows and perhaps a decrease in tidal range. In 2002, the gates at the dike were open for two months for a survey campaign and the seaweed harvest in the winter 2002-2003 was quite good. However, the problem may be linked to totally different causes, e.g. increase in industrial pollution discharge, chemicals used in the disinfection methods of washing seaweed, or change in water pH after the volcanic eruptions of the Unzen mountain in 1992 and 1993. The purpose of the research is to elucidate present condition of the Ariake Sea and past history using by radiometric methods, and obtained useful information will resolve the environmental status of Ariake Sea and give us answers way to save the Ariake Sea. Sea sediment cores were taken on board in 2003 at several points covering the Ariake sea. Two cores taken in inner area of the sea were sectioned at every 2 cm intervals and subjected to gamma spectrometry to determine sedimentation

  5. Uranium in the Black Sea

    International Nuclear Information System (INIS)

    Babinets, A.E.; Zhorov, V.A.; Bezborodov, A.A.; Kobylyanskaya, A.G.; Solov'eva, L.V.; Urdenko, V.A.

    1975-01-01

    Water samples for uranium analysis have been collected over the entire Black Sea, from the surface to the sea floor. As distinct from the previously known facts, it has been established that the uranium content in different parts of the sea appears to vary both in extent and with depth. A behaviour of uranium is governed by redox conditions of the environment. A decrease in pH value of water to 7.5 and a change of Eh value from +0.4 to -0.2 v lead to reduction of U 6+ → U 4+ and ensure higher sorption properties of the solid phases. The reducing reaction is proved possible through the calculated data. It is shown that the rate of uranium isolation is increasing with depth and its content is going down. Using optical properties of water, a hydrogeochemical behaviour of organic matter and uranium in water thickness is explained. Role of organic matter and mineral components in the uranium deposition is described. Sorption of U 6+ ions on twelve components, which constitute a base of suspensions and floor sediments, has been also studied [ru

  6. Urticaria caused by the slug (Lepidoptera: Limacodidae)

    African Journals Online (AJOL)

    00 caterpillar venoms. In: Venomous animals and their venomS. Vol. 3, (OOs) Bilcher~ W. & Buck:]ey, f.E. Academic Press, New York. PINHEY, E.C.G. 1975. Moths of Southem Africa. Tafelbcrg Publishers,. Cape Town, South Africa. ROTHSCHILD, M., VON EUW, 1. & REICHSTEfN, T. 1972. Some problems connected with ...

  7. Radioactivity in the Arctic Seas. Report for the International Arctic Seas Assessment Project (IASAP)

    International Nuclear Information System (INIS)

    1999-04-01

    This report provides comprehensive information on environmental conditions in the Arctic Seas as required for the study of possible radiological consequences from dumped high level radioactive wastes in the Kara Sea. The report describes the oceanography of the regions, with emphasis on the Kara and Barents Seas, including the East Novaya Zemlya Fjords. The ecological description concentrates on biological production, marine food-weds and fisheries in the Arctic Seas. The report presents data on radionuclide concentrations in the Kara and Barents Seas and uses these data to estimate the inventories of radionuclides currently in the marine environment of the Kara and Barents Seas

  8. Sea-ice cover in the Nordic Seas and the sensitivity to Atlantic water temperatures

    Science.gov (United States)

    Jensen, Mari F.; Nisancioglu, Kerim H.; Spall, Michael A.

    2017-04-01

    Changes in the sea-ice cover of the Nordic Seas have been proposed to play a key role for the dramatic temperature excursions associated with the Dansgaard-Oeschger events during the last glacial. However, with its proximity to the warm Atlantic water, how a sea-ice cover can persist in the Nordic Seas is not well understood. In this study, we apply an eddy-resolving configuration of the Massachusetts Institute of Technology general circulation model with an idealized topography to study the presence of sea ice in a Nordic Seas-like domain. We assume an infinite amount of warm Atlantic water present in the south by restoring the southern area to constant temperatures. The sea-surface temperatures are restored toward cold, atmospheric temperatures, and as a result, sea ice is present in the interior of the domain. However, the sea-ice cover in the margins of the Nordic Seas, an area with a warm, cyclonic boundary current, is sensitive to the amount of heat entering the domain, i.e., the restoring temperature in the south. When the temperature of the warm, cyclonic boundary current is high, the margins are free of sea ice and heat is released to the atmosphere. We show that with a small reduction in the temperature of the incoming Atlantic water, the Nordic Seas-like domain is fully covered in sea ice. Warm water is still entering the Nordic Seas, however, this happens at depths below a cold, fresh surface layer produced by melted sea ice. Consequently, the heat release to the atmosphere is reduced along with the eddy heat fluxes. Results suggest a threshold value in the amount of heat entering the Nordic Seas before the sea-ice cover disappears in the margins. We study the sensitivity of this threshold to changes in atmospheric temperatures and vertical diffusivity.

  9. Sea Ice Drift Monitoring in the Bohai Sea Based on GF4 Satellite

    Science.gov (United States)

    Zhao, Y.; Wei, P.; Zhu, H.; Xing, B.

    2018-04-01

    The Bohai Sea is the inland sea with the highest latitude in China. In winter, the phenomenon of freezing occurs in the Bohai Sea due to frequent cold wave influx. According to historical records, there have been three serious ice packs in the Bohai Sea in the past 50 years which caused heavy losses to our economy. Therefore, it is of great significance to monitor the drift of sea ice and sea ice in the Bohai Sea. The GF4 image has the advantages of short imaging time and high spatial resolution. Based on the GF4 satellite images, the three methods of SIFT (Scale invariant feature - the transform and Scale invariant feature transform), MCC (maximum cross-correlation method) and sift combined with MCC are used to monitor sea ice drift and calculate the speed and direction of sea ice drift, the three calculation results are compared and analyzed by using expert interpretation and historical statistical data to carry out remote sensing monitoring of sea ice drift results. The experimental results show that the experimental results of the three methods are in accordance with expert interpretation and historical statistics. Therefore, the GF4 remote sensing satellite images have the ability to monitor sea ice drift and can be used for drift monitoring of sea ice in the Bohai Sea.

  10. Sea Surface Temperature Climate Data Record for the North Sea and Baltic Sea

    DEFF Research Database (Denmark)

    Høyer, Jacob L.; Karagali, Ioanna

    2016-01-01

    A 30-yr climate data record (CDR) of sea surface temperature (SST) has been produced with daily gap-free analysis fields for the North Sea and the Baltic Sea region from 1982 to 2012 by combining the Pathfinder AVHRR satellite data record with the Along-Track Scanning Radiometer (ATSR) Reprocessing...... for Climate (ARC) dataset and with in situ observations. A dynamical bias correction scheme adjusts the Pathfinder observations toward the ARC and in situ observations. Largest Pathfinder-ARC differences are found in the summer months, when the Pathfinder observations are up to 0.4 °C colder than the ARC...... observations on average. Validation against independent in situ observations shows a very stable performance of the data record, with a mean difference of -0.06 °C compared to moored buoys and a 0.46 °C standard deviation of the differences. The mean annual biases of the SST CDR are small for all years...

  11. Winter sea ice export from the Laptev Sea preconditions the local summer sea ice cover and fast ice decay

    Directory of Open Access Journals (Sweden)

    P. Itkin

    2017-10-01

    Full Text Available Ice retreat in the eastern Eurasian Arctic is a consequence of atmospheric and oceanic processes and regional feedback mechanisms acting on the ice cover, both in winter and summer. A correct representation of these processes in numerical models is important, since it will improve predictions of sea ice anomalies along the Northeast Passage and beyond. In this study, we highlight the importance of winter ice dynamics for local summer sea ice anomalies in thickness, volume and extent. By means of airborne sea ice thickness surveys made over pack ice areas in the south-eastern Laptev Sea, we show that years of offshore-directed sea ice transport have a thinning effect on the late-winter sea ice cover. To confirm the preconditioning effect of enhanced offshore advection in late winter on the summer sea ice cover, we perform a sensitivity study using a numerical model. Results verify that the preconditioning effect plays a bigger role for the regional ice extent. Furthermore, they indicate an increase in volume export from the Laptev Sea as a consequence of enhanced offshore advection, which has far-reaching consequences for the entire Arctic sea ice mass balance. Moreover we show that ice dynamics in winter not only preconditions local summer ice extent, but also accelerate fast-ice decay.

  12. Cleaning up the sea bed in the North Sea. 1994

    International Nuclear Information System (INIS)

    1995-01-01

    The yearly raid was executed in an efficient way and without excess technical equipment interruptions. The vessel ''Lance'' owned by the Norwegian Sea Mapping Authorities which was used for the sonar mapping of the sea bed, was equipped with a Klein 531T side seeking sonar, a Simrad echo sounder of the type EM100 (multiray) and differential GPS navigation system. The executive committee has earlier expressed desire for a strengthening of the co-operation with the Norwegian Sea Mapping Authorities. The use of the vessel was in accordance with this wish. Stolt Comex Seaway A/S used the vessel M/S ''Seaway Commander'' and the underwater vessel ''Solo'' for the cleaning up project. The systems worked satisfactory during the entire operation. The cleaning operation was in 1994 carried out in 2 sections. The Petroleum Directorate agreed to letting the M/S ''Seaway Commander'' complete the project for Norsk Hydro at the Troll field in order to avoid delays in the Troll Oil project. In both periods there were good weather conditions. There was no extensive discontinuations due to the weather. During the two periods of 13,5 days 259 out of 370 positions were investigated visually through the systems. This is in average about 20 inspected positions a day. The reason for the high average is that the sailing distances are short between the positions and the findings corresponded to stated positions and sonar interpretations. Also this year there was installed a side seeking sonar in the underwater vessel which resulted in reduced investigation time at each aim. It was possible with this type of sonar to identify the goal quicker and to seek during transit between goals at moderate distances. Few articles with certainty contributed by the petroleum activities were retrieved

  13. Recovery of Waterflood Residual Oil Using Alkali, Surfactant and Polymer Slugs in Radial Cores Récupération d'huile résiduelle par injection d'eau améliorée de produits alcalins, de tensio-actifs et de polymères dans des carottes radiales

    Directory of Open Access Journals (Sweden)

    Nasr-El-Din H. A.

    2006-11-01

    Full Text Available An experimental study has been conducted to examine mobilization and recovery of waterflood residual oil in radial cores. Alkali, surfactant, and polymer slugs of various compositions, sizes and sequences were tested. Core flood experiments were conducted with unfired radial Berea sandstone disks at a flow rate of 8 cm3/h. David Lloydminster crude oil (total acid number of 0. 45 mg KOH/g oil was used. The results of the present work showed that the composition and sequence of the injected chemical slug play an important role in mobilization and recovery of residual oil. For slugs lacking either mobility control, or low interfacial tension, no oil bank was formed and tertiary oil recovery was less than 20% Sor. A significant oil bank and tertiary oil recovery up to 70 % Sor were obtained with slugs having mobility control and low interfacial tension. However, maximum oil cut, incre-mental oil recovery and surfactant propagation were found to be functions of the alkali content in the slug. The incremental oil recovery, oil cut and slug injectivity greatly improved as the alkali concentration (sodium carbonate in the combined slug was increased. A slight delay in surfactant breakthrough and a significantly slower rate of surfactant propagation were observed at higher sodium carbonate concentrations. Une étude expérimentale ayant pour but d'examiner la mobilisation et la récupération assistée d'huile résiduelle, à la suite d'un déplacement par l'eau en milieu poreux, a été conduite. Des bouchons de produit alcalin, de surfactant et de polymère, ayant des compositions, grosseurs et séquences d'injection variées, furent essayés. Les déplacements en milieu poreux furent conduits en utilisant des carottes de grès berea (non traités à haute température et un débit de 8,0 cm3/h. Pour ce faire, on utilisa de l'huile de David Lloydminster (ayant un nombre acide de 0,45 mg KOH/g d'huile. Les résultats de ce travail ont démontré que la

  14. The Costs of a Cleaner baltic Sea

    DEFF Research Database (Denmark)

    Brodersen, Sisse Liv; Konrad, Maria Theresia Hedegaard; Hasler, Berit

    2009-01-01

    In 2007 the Helcom (The Helsinki Comity), representing most of the countries around the Baltic, made an agreement for the future of the Baltic Sea, on reducing the nutrient input to the Baltic Sea and thereby avert further environmental damage, called the Baltic Sea Action Plan (BSAP). One...... of the results was nutrient reduction targets for each country - the BSAP targets. Because the Baltic Sea is such an international marine area, receiving pollutants from many  countries, an international approach is necessary to make effective solutions. But is the BSAP the most cost-effective solution...... to the regulation of the Baltic Sea? And does the BSAP result in cost-effective reductions in the different countries, which is a requirement of the Water Framework Directive and the Marine Strategy Directive?   These questions are studied and answered using a cost minimisation model for the Baltic sea, initially...

  15. Evaporation of boric acid from sea water

    Energy Technology Data Exchange (ETDEWEB)

    Gast, J A; Thompson, T G

    1959-01-01

    Previous investigators have shown that the boron-chlorinity ratios of rain waters are many times greater than the boron-chlorinity ratio of sea water. The presence of boron in the atmosphere has been attributed to sea spray, volcanic activity, accumulation in dust, evaporation from plants, and industrial pollution. In this paper data are presented to demonstrate that boric acid in sea water has a vapor pressure at ordinary temperatures of the sea and, when sea water evaporates, boric acid occurs in the condensate of the water vapor. It is postulated that, while some of the boron in the atmosphere can be attributed to the sources mentioned above, most of the boric acid results from evaporation from the sea.

  16. Sea water pipeline for nuclear power plant

    International Nuclear Information System (INIS)

    Ueno, Ken-ichi.

    1992-01-01

    Heating coils, for example, are wound around sea water pipelines as a heater. The outer wall surface of the sea water pipelines is heated by the heating coils. The inner wall surfaces of the sea water pipelines can be warmed to higher than a predetermined temperature by heating the outer wall surfaces to die out marine organisms deposited at the inner surfaces. Further, thermocouples for the external wall and the internal wall are disposed so that the temperature at the inner wall surface of the sea water pipelines can be controlled. Further, a temperature keeping material is disposed at the external surface of the sea water system pipelines. With such a constitution, the marine organisms deposited on the internal wall surface of the sea water system pipelines are died out to suppress the deposition amount of the marine organisms. Accordingly, the maintenance and the operation reliability is improved after maintenance. (I.N.)

  17. First biological measurements of deep-sea corals from the Red Sea.

    Science.gov (United States)

    Roder, C; Berumen, M L; Bouwmeester, J; Papathanassiou, E; Al-Suwailem, A; Voolstra, C R

    2013-10-03

    It is usually assumed that metabolic constraints restrict deep-sea corals to cold-water habitats, with 'deep-sea' and 'cold-water' corals often used as synonymous. Here we report on the first measurements of biological characters of deep-sea corals from the central Red Sea, where they occur at temperatures exceeding 20°C in highly oligotrophic and oxygen-limited waters. Low respiration rates, low calcification rates, and minimized tissue cover indicate that a reduced metabolism is one of the key adaptations to prevailing environmental conditions. We investigated four sites and encountered six species of which at least two appear to be undescribed. One species is previously reported from the Red Sea but occurs in deep cold waters outside the Red Sea raising interesting questions about presumed environmental constraints for other deep-sea corals. Our findings suggest that the present understanding of deep-sea coral persistence and resilience needs to be revisited.

  18. Oceanographic cruise: Coral Sea, Arafura Sea, and Java Trench, April - May 1969 (NODC Accession 7100914)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This report contains oceanographic data which was obtained aboard HMAS DIAMANTINA during an oceanographic cruise in the Coral Sea, Arafura Sea, and Java Trench...

  19. GHRSST Level 4 ODYSSEA Mediterranean Sea Regional Foundation Sea Surface Temperature Analysis (GDS version 1)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A Group for High Resolution Sea Surface Temperature (GHRSST) Level 4 sea surface temperature analysis produced daily on an operational basis at Ifremer/CERSAT...

  20. The lowering of sea surface temperature in the east central Arabian sea associated with a cyclone

    Digital Repository Service at National Institute of Oceanography (India)

    Murty, V.S.N.; Rao, D.P.; Sastry, J.S.

    An analysis of thermal Structure in the East Central Arabian Sea associated with a moderate cyclone is presented. The heat storage and the heat budget components have been computed. Under the influence of the cyclone the Sea Surface Temperature (SST...

  1. GHRSST Level 4 EUR Mediterranean Sea Regional Foundation Sea Surface Temperature Analysis (GDS version 2)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A Group for High Resolution Sea Surface Temperature (GHRSST) Level 4 sea surface temperature analysis produced daily by Ifremer/CERSAT (France) using optimal...

  2. First biological measurements of deep-sea corals from the Red Sea.

    KAUST Repository

    Roder, Cornelia

    2013-10-03

    It is usually assumed that metabolic constraints restrict deep-sea corals to cold-water habitats, with \\'deep-sea\\' and \\'cold-water\\' corals often used as synonymous. Here we report on the first measurements of biological characters of deep-sea corals from the central Red Sea, where they occur at temperatures exceeding 20°C in highly oligotrophic and oxygen-limited waters. Low respiration rates, low calcification rates, and minimized tissue cover indicate that a reduced metabolism is one of the key adaptations to prevailing environmental conditions. We investigated four sites and encountered six species of which at least two appear to be undescribed. One species is previously reported from the Red Sea but occurs in deep cold waters outside the Red Sea raising interesting questions about presumed environmental constraints for other deep-sea corals. Our findings suggest that the present understanding of deep-sea coral persistence and resilience needs to be revisited.

  3. A deep sea community at the Kebrit brine pool in the Red Sea

    KAUST Repository

    Vestheim, Hege; Kaartvedt, Stein

    2015-01-01

    Approximately 25 deep sea brine pools occur along the mid axis of the Red Sea. These hypersaline, anoxic, and acidic environments have previously been reported to host diverse microbial communities. We visited the Kebrit brine pool in April 2013

  4. Speciation studies of cobalt in sea water

    International Nuclear Information System (INIS)

    Toteja, R.S.D.; Sudersanan, M.; Iyer, R.K.

    1995-01-01

    Recent results on the speciation of cobalt in simulated and actual sea water is reported using ion exchangers. The influence of magnesium ions in affecting the composition of ion exchangers and subsequent interpretation of the results is discussed. The results indicated that Co +2 may predominate in both the simulated and actual sea water and the presence of other constituents in sea water does not affect the nature of complex species present. (author). 2 refs., 3 tabs., 1 fig

  5. The International Arctic Seas Assessment Project

    International Nuclear Information System (INIS)

    Linsley, G.S.; Sjoeblom, K.L.

    1994-01-01

    The International Arctic Seas Assessment Project (IASAP) was initiated in 1993 to address widespread concern over the possible health and environmental impacts associated with the radioactive waste dumped into the shallow waters of the Arctic Seas. This article discusses the project with these general topics: A brief history of dumping activities; the international control system; perspectives on arctic Seas dumping; the IASAP aims and implementation; the IASAP work plan and progress. 2 figs

  6. Multiscale Models of Melting Arctic Sea Ice

    Science.gov (United States)

    2014-09-30

    Sea ice reflectance or albedo , a key parameter in climate modeling, is primarily determined by melt pond and ice floe configurations. Ice - albedo ...determine their albedo - a key parameter in climate modeling. Here we explore the possibility of a conceptual sea ice climate model passing through a...bifurcation points. Ising model for melt ponds on Arctic sea ice Y. Ma, I. Sudakov, and K. M. Golden Abstract: The albedo of melting

  7. Context awareness and sensitivity in SEA implementation

    International Nuclear Information System (INIS)

    Hilding-Rydevik, Tuija; Bjarnadottir, Holmfridur

    2007-01-01

    The Impact Assessment research community repeatedly asserts that the implementation of Strategic Environmental Assessment (SEA) should take the issue of context into consideration. The primary aim of this paper then is to attempt to give substance to the concept of 'context' in relation to the implementation of SEA. The second aim is to discuss the relevance of context consciousness and sensitivity in relation to one of the main aims given to SEA implementation i.e. to contribute to the 'integration' of environmental perspectives in planning processes. Context must be defined in relation to a certain question. In this paper the question in focus is the assumption that SEA implementation will contribute to integration of environmental issues in planning processes. Research results relating to the use of environmental tools, like for example SEA, and experiences of integration efforts, strongly indicate that the use of a single tool like SEA is not enough to achieve this integration. The current 'context free' normative and procedural assumptions concerning the aim of SEA implementation and 'best practice' in term of SEA can be criticised on the same grounds as normative and procedural planning theories, as being context free. The assumptions behind the current formulations of the aim and best practice of SEA need to be revisited. A firm empirical and theoretical knowledge and discussion is needed, especially in relation to the issue of context and integration. This paper provides a starting point in this direction

  8. Sea level rise in the Arctic Ocean

    OpenAIRE

    Proshutinsky, Andrey; Pavlov, Vladimir; Bourke, Robert H.

    2001-01-01

    The article of record as published may be found at http://dx.doi.org/10.1029/2000GL012760 About 60 tide-gauge stations in the Kara, Laptev, East-Siberian and Chukchi Seas have recorded the sea level change from the 1950s through 1990s. Over this 40-year period, most of these stations show a significant sea level rise (SLR). In light of global change, this SLR could be a manifestation of warming in the Artic coupled with a decrease of sea ice extent, warming of Atlantic waters, changes in...

  9. Arctic tides from GPS on sea ice

    OpenAIRE

    Kildegaard Rose, Stine; Skourup, Henriette; Forsberg, René

    2012-01-01

    The presence of sea-ice in the Arctic Ocean plays a significant role in the Arctic climate. Sea ice dampens the ocean tide amplitude with the result that global tidal models which use only astronomical data perform less accurately in the polar regions. This study presents a kinematic processing of Global Positioning System (GPS) buoys placed on sea-ice at five different sites north of Greenland for the study of sea level height and tidal analysis to improve tidal models in the Central Arctic....

  10. [Reflectance of sea ice in Liaodong Bay].

    Science.gov (United States)

    Xu, Zhan-tang; Yang, Yue-zhong; Wang, Gui-fen; Cao, Wen-xi; Kong, Xiang-peng

    2010-07-01

    In the present study, the relationships between sea ice albedo and the bidirectional reflectance distribution in Liaodong Bay were investigated. The results indicate that: (1) sea ice albedo alpha(lambda) is closely related to the components of sea ice, the higher the particulate concentration in sea ice surface is, the lower the sea ice albedo alpha(lambda) is. On the contrary, the higher the bubble concentration in sea ice is, the higher sea ice albedo alpha(lambda) is. (2) Sea ice albedo alpha(lambda) is similar to the bidirectional reflectance factor R(f) when the probe locates at nadir. The R(f) would increase with the increase in detector zenith theta, and the correlation between R(f) and the detector azimuth would gradually increase. When the theta is located at solar zenith 63 degrees, the R(f) would reach the maximum, and the strongest correlation is also shown between the R(f) and the detector azimuth. (3) Different types of sea ice would have the different anisotropic reflectance factors.

  11. Parasites in the Wadden Sea food web

    Science.gov (United States)

    Thieltges, David W.; Engelsma, Marc Y.; Wendling, Carolin C.; Wegner, K. Mathias

    2013-09-01

    While the free-living fauna of the Wadden Sea has received much interest, little is known on the distribution and effects of parasites in the Wadden Sea food web. However, recent studies on this special type of trophic interaction indicate a high diversity of parasites in the Wadden Sea and suggest a multitude of effects on the hosts. This also includes effects on specific predator-prey relationships and the general structure of the food web. Focussing on molluscs, a major group in the Wadden Sea in terms of biomass and abundance and an important link between primary producers and predators, we review existing studies and exemplify the ecological role of parasites in the Wadden Sea food web. First, we give a brief inventory of parasites occurring in the Wadden Sea, ranging from microparasites (e.g. protozoa, bacteria) to macroparasites (e.g. helminths, parasitic copepods) and discuss the effects of spatial scale on heterogeneities in infection levels. We then demonstrate how parasites can affect host population dynamics by acting as a strong mortality factor, causing mollusc mass mortalities. In addition, we will exemplify how parasites can mediate the interaction strength of predator-prey relationships and affect the topological structure of the Wadden Sea food web as a whole. Finally, we highlight some ongoing changes regarding parasitism in the Wadden Sea in the course of global change (e.g. species introduction, climate change) and identify important future research questions to entangle the role of parasites in the Wadden Sea food web.

  12. The economics of fishing the high seas.

    Science.gov (United States)

    Sala, Enric; Mayorga, Juan; Costello, Christopher; Kroodsma, David; Palomares, Maria L D; Pauly, Daniel; Sumaila, U Rashid; Zeller, Dirk

    2018-06-01

    While the ecological impacts of fishing the waters beyond national jurisdiction (the "high seas") have been widely studied, the economic rationale is more difficult to ascertain because of scarce data on the costs and revenues of the fleets that fish there. Newly compiled satellite data and machine learning now allow us to track individual fishing vessels on the high seas in near real time. These technological advances help us quantify high-seas fishing effort, costs, and benefits, and assess whether, where, and when high-seas fishing makes economic sense. We characterize the global high-seas fishing fleet and report the economic benefits of fishing the high seas globally, nationally, and at the scale of individual fleets. Our results suggest that fishing at the current scale is enabled by large government subsidies, without which as much as 54% of the present high-seas fishing grounds would be unprofitable at current fishing rates. The patterns of fishing profitability vary widely between countries, types of fishing, and distance to port. Deep-sea bottom trawling often produces net economic benefits only thanks to subsidies, and much fishing by the world's largest fishing fleets would largely be unprofitable without subsidies and low labor costs. These results support recent calls for subsidy and fishery management reforms on the high seas.

  13. Do Indicators Influence Communication in SEA?

    DEFF Research Database (Denmark)

    Gao, Jingjing; Kørnøv, Lone; Christensen, Per

    2013-01-01

    Indicators have become one of the primary tools for Strategic Environmental Assessment (SEA) in the Chinese context, but what does this use of indicators mean for communication within the SEA processes? This article explores how the selection and use of indicators influence the communication...... between different stakeholders involved in SEA. The article provides a conceptual communication model covering directions and level of communication. Using this model on empirical findings from interviews with two specific SEA cases and from general experience collected through an online survey...

  14. Environmental security of coastal seas

    International Nuclear Information System (INIS)

    Valkovic, Vladivoj; Sudac, Davorin; Nad, Karlo; Obhodas, Jasmina; Kollar, Robert; Matika, Dario

    2008-01-01

    Full text: The bottoms of the coastal seas are contaminated by many man-made objects including a variety of ammunition. This contamination is world wide spread with some areas being highly polluted presenting a serious threat to local population and to visitors as well. All littoral nations are investing lots of effort into the remediation of their coastal areas. In this report an effort to identify the nature of the object on the sea bottom is presented. Once the presence of the anomaly on the bottom of the shallow coastal sea water is confirmed (by visual identification and by using one or several sensors, namely magnetometer, sonar and optical cameras) it is necessary to establish if it contains explosive and/or chemical warfare charge. In our work we propose this to be performed by using neutron sensor installed within an underwater vessel - 'Surveyor'. When positioned above the object, or to its side, the system inspects the object for the presence of the threat material by using alpha particle tagged neutrons from the sealed tube d+t neutron generator. The inside of the first prototype of the underwater system 'Surveyor' containing neutron generator, shielding and gamma ray detector is shown in figure. The neutron generator used by the 'Surveyor' is rotated by two step motors so that different volume elements chosen by the relative position of the neutron generator and gamma ray detector could be inspected. In such a way a profile of concentrations could also be measured. The preliminary results from the laboratory tests are presented

  15. The North Sea contracting industry

    International Nuclear Information System (INIS)

    Wright, P.J.C.

    1996-09-01

    The North Sea Contracting Industry provides in-depth profiles of major contracting organisations including manpower, facilities, expertise, future directions and financial details. It addresses key issues such as: how will the role of operators and contractors change toward 2000 and beyond?; how will the contractor-operator relationship develop?; will the contractors take a more speculative role in projects such as leasing and contract to produce?; does the future belong to broad skilled providers or small specialised niche players, or both?; and how will rapid technological improvements affect the industry? (author)

  16. Towards Good Order at Sea

    DEFF Research Database (Denmark)

    Mandrup, Thomas; Vreÿ, Francois

    . The problems originating from the resultant “bad order at sea” can be directly felt on land, when smuggling, terrorism and related criminal activities operate more or less unhindered. The book provides an important mapping of the challenges preventing good order at sea off the African coast and East Africa...... in particular. The chapters offer suggestions for increased maritime security in the future and go some way to assist the African Union to implement its maritime strategy and raise the maritime security awareness of its member states....

  17. Banning nuclear power at sea

    International Nuclear Information System (INIS)

    Handler, J.

    1993-01-01

    This article argues that now that the East-West conflict is over, nuclear-powered vessels should be retired. Nuclear-powered ships and submarines lack military missions, are expensive to build and operate, generate large amounts of long-lived deadly nuclear waste from their normal operations and when they are decommissioned, and are subject to accidents or deliberate attack which can result in the sinking of nuclear reactors and the release of radiation. With the costs of nuclear-powered vessels mounting, the time has come to ban nuclear power at sea. (author)

  18. Authigenic gypsum in a deep sea core from Southeastern Arabian Sea

    Digital Repository Service at National Institute of Oceanography (India)

    Guptha, M.V.S.

    Authigenic gypsum has been encountered in a deep sea core RC9-157 from the southeastern Arabian Sea at a depth of 4111 m which is a zone of lysocline. The formation of gypsum in the deep sea region is attributed to the prevailing sulphate rich...

  19. Potential of sea level rise impact on South China Sea: a preliminary ...

    African Journals Online (AJOL)

    The effect of the sea level rise was involved the existence of sea water intrusion and coastal erosion phenomenon in the coastal of Terengganu. This study aim to determine fluctuation of high and low tides of the South China Sea in their relation to water quality value of Marang and Paka Rivers as well as from wells ...

  20. Sea Turtle Conservation on Bonaire. Sea Turtle Club Bonaire 1997. Project Report

    NARCIS (Netherlands)

    Schuit, M.; Put, van A.L.L.M.; Valkering, N.P.; Eijck, van T.J.W.

    1998-01-01

    The Sea Turtle Club Bonaire (STCB) is a non-governmental, non-profit organization. Its main goal is the conservation of the sea turtles that occur on Bonaire. To reach this goal, annual projects are undertaken, such as research and the promotion of public awareness on sea turtle conservation. The

  1. 50 CFR 697.12 - At-sea sea sampler/observer coverage.

    Science.gov (United States)

    2010-10-01

    ... sampler/observer access to and use of the vessel's communications equipment and personnel upon request for...) Allow the sea sampler/observer to inspect and copy the vessel's log, communications log, and records... must: (1) Notify the sea sampler/observer of any sea turtles, marine mammals, or other specimens taken...

  2. Real-Time Optimization of a maturing North Sea gas asset with production constraints

    NARCIS (Netherlands)

    Linden, R.J.P. van der; Busking, T.E.

    2013-01-01

    As gas and oil fields mature their operation becomes increasingly more complex, due to complex process dynamics, like slugging, gas coning, water breakthrough, salt or hydrate deposition. Moreover these phenomena also lead to production constraints in the upstream facilities. This complexity asks

  3. Wind-sea surface temperature-sea ice relationship in the Chukchi-Beaufort Seas during autumn

    Science.gov (United States)

    Zhang, Jing; Stegall, Steve T.; Zhang, Xiangdong

    2018-03-01

    Dramatic climate changes, especially the largest sea ice retreat during September and October, in the Chukchi-Beaufort Seas could be a consequence of, and further enhance, complex air-ice-sea interactions. To detect these interaction signals, statistical relationships between surface wind speed, sea surface temperature (SST), and sea ice concentration (SIC) were analyzed. The results show a negative correlation between wind speed and SIC. The relationships between wind speed and SST are complicated by the presence of sea ice, with a negative correlation over open water but a positive correlation in sea ice dominated areas. The examination of spatial structures indicates that wind speed tends to increase when approaching the ice edge from open water and the area fully covered by sea ice. The anomalous downward radiation and thermal advection, as well as their regional distribution, play important roles in shaping these relationships, though wind-driven sub-grid scale boundary layer processes may also have contributions. Considering the feedback loop involved in the wind-SST-SIC relationships, climate model experiments would be required to further untangle the underlying complex physical processes.

  4. Filling regulatory gaps in high seas fisheries: discrete high seas fish stocks, deep-sea fisheries and vulnerable marine ecosystems

    NARCIS (Netherlands)

    Takei, Y.

    2008-01-01

    The present study examines the legal regime of high seas fisheries with a view to identifying regulatory gaps. The main research questions are as follows: 1. What general principles are applicable to high seas fisheries?; 2. What implications do these general principles have for new challenges in

  5. Processes driving sea ice variability in the Bering Sea in an eddying ocean/sea ice model: Mean seasonal cycle

    Science.gov (United States)

    Li, Linghan; McClean, Julie L.; Miller, Arthur J.; Eisenman, Ian; Hendershott, Myrl C.; Papadopoulos, Caroline A.

    2014-12-01

    The seasonal cycle of sea ice variability in the Bering Sea, together with the thermodynamic and dynamic processes that control it, are examined in a fine resolution (1/10°) global coupled ocean/sea-ice model configured in the Community Earth System Model (CESM) framework. The ocean/sea-ice model consists of the Los Alamos National Laboratory Parallel Ocean Program (POP) and the Los Alamos Sea Ice Model (CICE). The model was forced with time-varying reanalysis atmospheric forcing for the time period 1970-1989. This study focuses on the time period 1980-1989. The simulated seasonal-mean fields of sea ice concentration strongly resemble satellite-derived observations, as quantified by root-mean-square errors and pattern correlation coefficients. The sea ice energy budget reveals that the seasonal thermodynamic ice volume changes are dominated by the surface energy flux between the atmosphere and the ice in the northern region and by heat flux from the ocean to the ice along the southern ice edge, especially on the western side. The sea ice force balance analysis shows that sea ice motion is largely associated with wind stress. The force due to divergence of the internal ice stress tensor is large near the land boundaries in the north, and it is small in the central and southern ice-covered region. During winter, which dominates the annual mean, it is found that the simulated sea ice was mainly formed in the northern Bering Sea, with the maximum ice growth rate occurring along the coast due to cold air from northerly winds and ice motion away from the coast. South of St Lawrence Island, winds drive the model sea ice southwestward from the north to the southwestern part of the ice-covered region. Along the ice edge in the western Bering Sea, model sea ice is melted by warm ocean water, which is carried by the simulated Bering Slope Current flowing to the northwest, resulting in the S-shaped asymmetric ice edge. In spring and fall, similar thermodynamic and dynamic

  6. A heavy sea fog event over the Yellow Sea in March 2005: Analysis and numerical modeling

    Science.gov (United States)

    Gao, Shanhong; Lin, Hang; Shen, Biao; Fu, Gang

    2007-02-01

    In this paper, a heavy sea fog episode that occurred over the Yellow Sea on 9 March 2005 is investigated. The sea fog patch, with a spatial scale of several hundred kilometers at its mature stage, reduced visibility along the Shandong Peninsula coast to 100 m or much less at some sites. Satellite images, surface observations and soundings at islands and coasts, and analyses from the Japan Meteorology Agency (JMA) are used to describe and analyze this event. The analysis indicates that this sea fog can be categorized as advection cooling fog. The main features of this sea fog including fog area and its movement are reasonably reproduced by the Fifth-generation Pennsylvania State University/National Center for Atmospheric Research Mesoscale Model (MM5). Model results suggest that the formation and evolution of this event can be outlined as: (1) southerly warm/moist advection of low-level air resulted in a strong sea-surface-based inversion with a thickness of about 600 m; (2) when the inversion moved from the warmer East Sea to the colder Yellow Sea, a thermal internal boundary layer (TIBL) gradually formed at the base of the inversion while the sea fog grew in response to cooling and moistening by turbulence mixing; (3) the sea fog developed as the TIBL moved northward and (4) strong northerly cold and dry wind destroyed the TIBL and dissipated the sea fog. The principal findings of this study are that sea fog forms in response to relatively persistent southerly warm/moist wind and a cold sea surface, and that turbulence mixing by wind shear is the primary mechanism for the cooling and moistening the marine layer. In addition, the study of sensitivity experiments indicates that deterministic numerical modeling offers a promising approach to the prediction of sea fog over the Yellow Sea but it may be more efficient to consider ensemble numerical modeling because of the extreme sensitivity to model input.

  7. Legacy of the Sea Express

    International Nuclear Information System (INIS)

    Bennett, Ian

    1997-01-01

    In February 1996, an oil tanker, the Sea Empress, ran aground in high seas in Milford Haven in the United Kingdom. Over the course of a few days, 72,000 tonnes of crude oil and 360 tonnes of heavy fuel oil leaked from the ship into a maritime and coastal area of designated scientific importance and environmental sensitivity. The Countryside Council for Wales (CCW), who are responsible for nature conservation in the area, carried out immediate surveys of the coverage of oil on the coastline. The data was fed into the CCW's geographic information system (GIS) which also holds other spill-related and environmental information. The GIS provided an ideal storage and retrieval system to enable CCW rapidly to produce high quality maps of the affected area and accurately pinpoint the protected sites involved. In summer 1996, CCW carried out a second, more detailed survey. By this time the tides and mechanical recovery had dispersed all the major concentrations of oil. A thorough comparison of the two surveys will be carried out in order to assess and catalogue the removal of the oil by natural processes and the effectiveness of the shoreline treatment. (UK)

  8. RNA viruses in the sea.

    Science.gov (United States)

    Lang, Andrew S; Rise, Matthew L; Culley, Alexander I; Steward, Grieg F

    2009-03-01

    Viruses are ubiquitous in the sea and appear to outnumber all other forms of marine life by at least an order of magnitude. Through selective infection, viruses influence nutrient cycling, community structure, and evolution in the ocean. Over the past 20 years we have learned a great deal about the diversity and ecology of the viruses that constitute the marine virioplankton, but until recently the emphasis has been on DNA viruses. Along with expanding knowledge about RNA viruses that infect important marine animals, recent isolations of RNA viruses that infect single-celled eukaryotes and molecular analyses of the RNA virioplankton have revealed that marine RNA viruses are novel, widespread, and genetically diverse. Discoveries in marine RNA virology are broadening our understanding of the biology, ecology, and evolution of viruses, and the epidemiology of viral diseases, but there is still much that we need to learn about the ecology and diversity of RNA viruses before we can fully appreciate their contributions to the dynamics of marine ecosystems. As a step toward making sense of how RNA viruses contribute to the extraordinary viral diversity in the sea, we summarize in this review what is currently known about RNA viruses that infect marine organisms.

  9. Multisensor Analyzed Sea Ice Extent - Northern Hemisphere (MASIE-NH)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Multisensor Analyzed Sea Ice Extent Northern Hemisphere (MASIE-NH) products provide measurements of daily sea ice extent and sea ice edge boundary for the...

  10. Winter cooling in the northern Arabian Sea

    Digital Repository Service at National Institute of Oceanography (India)

    PrasannaKumar, S.; Prasad, T.G.

    forcing that leads to the observed high productivity during winter in the northern Arabian Sea. The weak northerly winds and increased solar insolation during the inter-monsoon period, led to the development of a highly stratified upper layer with warm sea...

  11. Coastal Sea Levels, Impacts, and Adaptation

    Directory of Open Access Journals (Sweden)

    Thomas Wahl

    2018-02-01

    Full Text Available Sea-level rise (SLR poses a great threat to approximately 10% of the world’s population residing in low-elevation coastal zones (i.e., land located up to 10 m of present-day mean sea-level (MSL[...

  12. Causes for contemporary regional sea level changes.

    Science.gov (United States)

    Stammer, Detlef; Cazenave, Anny; Ponte, Rui M; Tamisiea, Mark E

    2013-01-01

    Regional sea level changes can deviate substantially from those of the global mean, can vary on a broad range of timescales, and in some regions can even lead to a reversal of long-term global mean sea level trends. The underlying causes are associated with dynamic variations in the ocean circulation as part of climate modes of variability and with an isostatic adjustment of Earth's crust to past and ongoing changes in polar ice masses and continental water storage. Relative to the coastline, sea level is also affected by processes such as earthquakes and anthropogenically induced subsidence. Present-day regional sea level changes appear to be caused primarily by natural climate variability. However, the imprint of anthropogenic effects on regional sea level-whether due to changes in the atmospheric forcing or to mass variations in the system-will grow with time as climate change progresses, and toward the end of the twenty-first century, regional sea level patterns will be a superposition of climate variability modes and natural and anthropogenically induced static sea level patterns. Attribution and predictions of ongoing and future sea level changes require an expanded and sustained climate observing system.

  13. The carbon budget of the North Sea

    NARCIS (Netherlands)

    Thomas, H.; Bozec, Y.; Baar, H.J.W. de; Elkalay, K.; Frankignoulle, M.; Schiettecatte, L.-S.; Kattner, G.; Borges, A.V.; Gattuso, J.-P.

    2005-01-01

    A carbon budget has been established for the North Sea, a shelf sea on the NW European continental shelf. The carbon exchange fluxes with the North Atlantic Ocean dominate the gross carbon budget. The net carbon budget – more relevant to the issue of the contribution of the coastal ocean to the

  14. Source of Aegean Sea harbour porpoises

    DEFF Research Database (Denmark)

    Lockyer, Christina; Rosel, P. E.; Frantzis, A.

    2003-01-01

    Documented sightings of harbour porpoises in the Mediterranean are rare, although the species is common in the neighbouring North Atlantic and Black Sea. However, in the past 2 decades, 4 harbour porpoises Phocoena phocoena have been recorded in the northern Aegean Sea in the eastern Mediterranea...

  15. Salinity extrema in the Arabian Sea

    Digital Repository Service at National Institute of Oceanography (India)

    Shenoi, S.S.C.; Shetye, S.R.; Gouveia, A.D.; Michael, G.S.

    are described. Two of the maxima arise from the influence of Red Sea and the Persian Gulf Water. The third, which lies at the bottom of the Equatorial Surface Water, forms due to freshening at the surface of high salinity Arabian Sea near-surface waters...

  16. Sea level rise : A literature survey

    NARCIS (Netherlands)

    Oude Essink, G.H.P.

    1992-01-01

    In order to assess the impact of sea level rise on Water Management, it is useful to understand the mechanisrns that determine the level of the sea. In this study, a literature survey is executed to analyze these mechanisms. Climate plays a centra! role in these mechanisms, Climate mainly changes

  17. Red Sea as a source for bioprospecting

    KAUST Repository

    Kodzius, Rimantas

    2015-01-01

    King-Abdullah University of Science and Technology (KAUST) is located on the shores of the Red Sea in Saudi Arabia. The Red Sea is well known for its unique environment, harboring various microbes capable of surviving in salty brines. We collected

  18. Mesoscale Eddies in the Solomon Sea

    Science.gov (United States)

    Hristova, H. G.; Kessler, W. S.; McWilliams, J. C.; Molemaker, M. J.

    2011-12-01

    Water mass transformation in the strong equatorward flows through the Solomon Sea influences the properties of the Equatorial Undercurrent and subsequent cold tongue upwelling. High eddy activity in the interior Solomon Sea seen in altimetric sea surface height (SSH) and in several models may provide a mechanism for these transformations. We investigate these effects using a mesoscale (4-km resolution) sigma-coordinate (ROMS) model of the Solomon Sea nested in a basin solution, forced by a repeating seasonal cycle, and evaluated against observational data. The model generates a vigorous upper layer eddy field; some of these are apparently shed as the New Guinea Coastal Undercurrent threads through the complex topography of the region, others are independent of the strong western boundary current. We diagnose the scales and vertical structure of the eddies in different parts of the Solomon Sea to illuminate their generation processes and propagation characteristics, and compare these to observed eddy statistics. Hypotheses tested are that the Solomon Sea mesoscale eddies are generated locally by baroclinic instability, that the eddies are shed as the South Equatorial Current passes around and through the Solomon Island chain, that eddies are generated by the New Guinea Coastal Undercurrent, or that eddies occurring outside of the Solomon Sea propagate into the Solomon Sea. These different mechanisms have different implications for the resulting mixing and property fluxes. They also provide different interpretations for SSH signals observed from satellites (e.g., that will be observed by the upcoming SWOT satellite).

  19. Greenhouse warming and changes in sea level

    NARCIS (Netherlands)

    Oerlemans, J.

    1989-01-01

    It is likely that the anticipated warming due to the effect of increasing concentration of carbon dioxide and other greenhouse gases will lead to a further and faster rise in world mean sea level. There are many processes in the climate system controlling sea level, but the most important

  20. Working with Nature in Wadden Sea Ports

    NARCIS (Netherlands)

    Baptist, M.J.; Eekelen, van E.; Dankers, P.J.T.; Grasmeijer, B.; Kessel, van T.; Maren, van D.S.

    2017-01-01

    Wadden Sea ports are situated at the border of the UNESCO World Heritage site Wadden Sea. Because of the protected status of this area, developing new economic activities is not straightforward. However, maintaining and developing port activities is needed to safeguard the economic viability of the