WorldWideScience

Sample records for scout lead-in period

  1. Early response to sibutramine in patients not meeting current label criteria: preliminary analysis of SCOUT lead-in period

    DEFF Research Database (Denmark)

    Caterson, Ian; Coutinho, Walmir; Finer, Nick

    2010-01-01

    The Sibutramine Cardiovascular Outcomes (SCOUT) trial protocol defines a patient population predominantly outside current European Union label criteria. This article explores responses to sibutramine during the 6-week, single-blind, lead-in period between patients who conformed to the label...... requirements ("conformers") and those who did not ("nonconformers"). SCOUT is an ongoing, randomized, double-blind, placebo-controlled outcome trial in overweight/obese patients at high risk of a cardiovascular event. In total, 10,742 patients received sibutramine and weight management during the lead...... with sibutramine confirms its good tolerability and efficacy in patients who meet current label criteria. Preliminary data from high-risk patients for whom sibutramine is currently contraindicated suggest a low discontinuation rate and few serious adverse events but confirmation from the SCOUT outcome data...

  2. Early response to sibutramine in patients not meeting current label criteria: preliminary analysis of SCOUT lead-in period

    DEFF Research Database (Denmark)

    Caterson, Ian; Coutinho, Walmir; Finer, Nick

    2010-01-01

    pulse rate increases; median 1.5 bpm (nonconformers) vs. 3.0 bpm (conformers). There was a low incidence of serious adverse events (conformers: 1.0%; nonconformers: 2.8%) and ~93% of patients in both groups completed the 6-week period. The SCOUT lead-in period evaluating weight management...

  3. Blood pressure changes associated with sibutramine and weight management - an analysis from the 6-week lead-in period of the sibutramine cardiovascular outcomes trial (SCOUT)

    DEFF Research Database (Denmark)

    Sharma, A M; Caterson, I D; Coutinho, W

    2009-01-01

    OBJECTIVE: To explore vital sign changes among patient subgroups during the 6-week lead-in period of the sibutramine cardiovascular outcomes (SCOUT) trial. METHODS: SCOUT is an ongoing, double-blind, randomized, placebo-controlled outcome trial in overweight/obese patients at high risk of a cardi......OBJECTIVE: To explore vital sign changes among patient subgroups during the 6-week lead-in period of the sibutramine cardiovascular outcomes (SCOUT) trial. METHODS: SCOUT is an ongoing, double-blind, randomized, placebo-controlled outcome trial in overweight/obese patients at high risk...... of a cardiovascular event. During the 6-week lead-in period, 10,742 patients received sibutramine and weight management. Vital sign changes were assessed post hoc by initial blood pressure (mmHg) categorized as normal (or=140/>or=90); weight change...... categories (weight gain/no weight change, >0 to 2.5% weight loss, >2.5 to 5% weight loss and >5% weight loss) and current antihypertensive medication class use (none, one, or two or more). To assess the impact of sibutramine on blood pressure and pulse rate, only patients (N = 10,025) who reported no change...

  4. Weight and blood pressure response to weight management and sibutramine in diabetic and non-diabetic high-risk patients: an analysis from the 6-week lead-in period of the sibutramine cardiovascular outcomes (SCOUT) trial

    DEFF Research Database (Denmark)

    Van Gaal, L F; Caterson, I D; Coutinho, W

    2010-01-01

    To assess treatment responses to sibutramine and weight management in diabetic patients during the lead-in period of the Sibutramine Cardiovascular OUTcomes (SCOUT) trial.......To assess treatment responses to sibutramine and weight management in diabetic patients during the lead-in period of the Sibutramine Cardiovascular OUTcomes (SCOUT) trial....

  5. Reaching for the Stars: NASA Science for Girl Scouts (Girl Scout Stars)

    Science.gov (United States)

    DeVore, Edna; Harman, Pamela; Girl Scouts of the USA; Girl Scouts of Northern California; University of Arizona; Astronomical Society of the Pacific; Aires Scientific

    2017-01-01

    Girl Scout Stars aims to enhance STEM experiences for Girl Scouts in grades K-12. New space science badges are being created for every Girl Scout level. Using best practices, we engage girls and volunteers with the fundamental STEM concepts that underpin our human quest to explore the universe. Through early and sustained exposure to the people and assets of NASA and the excitement of NASA’s Mission, they explore STEM content, discoveries, and careers. Today’s tech savvy Girl Scout volunteers prefer just-in-time materials and asynchronous learning. The Volunteer Tool Kit taps into the wealth of NASA's online materials for the new space science badges. Training volunteers supports troop activities for the younger girls. For older girls, we enhance Girl Scout summer camp activities, support in-depth experiences at Univ. of Arizona’s Astronomy Camp, and “Destination” events for the 2017 total solar eclipse. We partner with the Night Sky Network to engage amateur astronomers with Girl Scouts. Univ. of Arizona also leads Astronomy Camp for Girl Scout volunteers. Aires Scientific leads eclipse preparation and summer sessions at NASA Goddard Space Flight Center for teams of volunteers, amateur astronomers and older Girl Scouts.There are 1,900,000 Girl Scouts and 800,000 volunteers in the USA. During development, we work with the Girl Scouts of Northern California (50,000 girl members and 31,000 volunteers) and expand across the USA to 121 Girl Scout councils over five years. SETI Institute leads the space science educators and scientists at Astronomical Society of the Pacific, Univ. of Arizona, and Aires Scientific. Girl Scouts of the USA leads dissemination of Girl Scout Stars with support of Girl Scouts of Northern California. Through professional development of Girl Scout volunteers, Girl Scout Stars enhances public science literacy. Girl Scout Stars supports the NASA Science Mission Directorate Science Education Objectives and NASA’s STEM Engagement and

  6. Differential changes in serum uric acid concentrations in sibutramine promoted weight loss in diabetes: results from four weeks of the lead-in period of the SCOUT trial

    DEFF Research Database (Denmark)

    Andersson, Charlotte; Weeke, Peter; Brendorp, Bente

    2009-01-01

    ABSTRACT: BACKGROUND AND AIMS: Elevated levels of serum uric acid are associated with an increased risk of cardiovascular morbidity and mortality. The response of uric acid to weight loss therapy (lifestyle plus sibutramine) in an overweight and obese cardiovascular high risk population was studied....... METHODS AND RESULTS: Data from a four week single-blind lead-in period of the Sibutramine Cardiovascular OUTcomes (SCOUT) study were analyzed. 2584 patients (24%) had diabetes mellitus (DM) only, 1748 (16%) had cardiovascular disease (CVD) only and 6397 (60%) had both DM + CVD. Uric acid concentrations...... significantly more in patients without DM (p sibutramine induced lower uric acid levels...

  7. Girl Scout Stars: Engaging Girl Scouts in the 2017 Total Eclipse

    Science.gov (United States)

    Harman, P. K.

    2017-12-01

    Reaching for the Stars: NASA Science for Girl Scouts (Girl Scout Stars) engages Girl Scouts in observing the 2017 eclipse. Three councils are host-sponsors of Girl Scout Total Eclipse Destinations,. Total Eclipse of the Heartland, sponsored by Girl Scouts of Southern Illinois, begins with planetarium, and science center visits in St. Louis, and transits to Carbondale for the eclipse. The Great Eclipse Adventure, sponsored by the Girl Scouts of the Missouri Heartland, features hands-on science activities led by Astronomy and Physics faculty and grad students at University of Missouri, Columbia, MO, and observing the eclipse at a camp nearby. Eyes to the Sky: A Once in a Lifetime Destination, by the Girl Scouts of South Carolina - Mountains to Midlands, visits a Challenger Center, a planetarium, and observatory, and culminates at Camp MaBak, Marietta, SC. Girl Scout Destinations are travel adventures, for individual girls ages 11 and older, that are inspiring, life-changing experiences. Destinations are determined via an application and review process by Girls Scouts of the USA. Girl Scout Stars also developed an Eclipse Activity Guide and kit box of materials, distributed the materials to 91 Girl Scout Councils, and delivered webinar training to councils. The eclipse materials enrich the girls' summer camp experiences with activities that promote understanding the Sun-Earth-Moon relationship, the solar system and safe eclipse viewing; and that feature science practices. Examples of the reach of the kit boxes are Girl Scouts of Montana and Wyoming Total Eclipse Event in Casper, WY, and the Girl Scouts of Northern California summer camps featuring the activities. In Girl Scouting, girls discover their skills, talents and what they care about; connect with other Girl Scouts and people in their community; and take action to change the world. This is called the Girl Scout Leadership Experience. With girl-led, hands on activities where girls can team up and work together

  8. Differential changes in serum uric acid concentrations in sibutramine promoted weight loss in diabetes: results from four weeks of the lead-in period of the SCOUT trial

    Directory of Open Access Journals (Sweden)

    Caterson Ian D

    2009-10-01

    Full Text Available Abstract Background and aims Elevated levels of serum uric acid are associated with an increased risk of cardiovascular morbidity and mortality. The response of uric acid to weight loss therapy (lifestyle plus sibutramine in an overweight and obese cardiovascular high risk population was studied. Methods and results Data from a four week single-blind lead-in period of the Sibutramine Cardiovascular OUTcomes (SCOUT study were analyzed. 2584 patients (24% had diabetes mellitus (DM only, 1748 (16% had cardiovascular disease (CVD only and 6397 (60% had both DM + CVD. Uric acid concentrations (mean ± standard deviation at screening were significantly higher among patients with CVD compared to patients without CVD (p Conclusion A four week daily intake of sibutramine and life style changes was associated with significant reductions in mean uric acid levels. Changes in renal glucose load in diabetes seem to counteract a potential uricosuric effect of sibutramine. Trial Registration The trial is registered at ClinicalTrial.gov number: NCT00234832.

  9. The weight lowering effect of sibutramine and its impact on serum lipids in cardiovascular high risk patients with and without type 2 diabetes mellitus - an analysis from the SCOUT lead-in period

    Directory of Open Access Journals (Sweden)

    James Philip T

    2010-02-01

    Full Text Available Abstract Background Obesity, type 2 diabetes mellitus (T2D and unhealthy blood lipid profile are strongly associated with the risk of developing cardiovascular disease (CVD. We examined whether blood lipid changes with short term administration of the weight lowering drug, sibutramine and lifestyle modification in obese and overweight high-risk patients was associated with T2D status at screening. Methods The Sibutramine Cardiovascular OUTcomes (SCOUT trial included obese and overweight patients at increased risk of cardiovascular events. All patients received guidance on diet and exercise plus once-daily 10 mg sibutramine during the 6-week, single blind lead-in period. Multivariable regression models were used to investigate factors associated with changes in lipid levels during the first four weeks of treatment. Results A total of 10 742 patients received at least one dose of sibutramine during the 6-week lead-in period of SCOUT. After four weeks, patients experienced mean reductions in low density lipoprotein (LDL-C 0.19 mmol/L, high density lipoprotein (HDL-C 0.019 mmol/L, very low density lipoprotein (VLDL-C 0.08 mmol/L, total cholesterol (TC 0.31 mmol/L and triglycerides 0.24 mmol/L (p 2 decrease in BMI in patients with T2D was associated with -0.09 mmol/L in LDL-C (P Conclusion Short term weight management with sibutramine therapy in obese or overweight high-risk patients induced significant mean reductions for all lipids. Those without T2D benefited most. Patients with hyperlipidaemia and the less obese patients also had greater falls in LDL-C and TC during weight loss. The trial is registered at ClinicalTrial.gov number: NCT00234832.

  10. Girl Scouts and Subject Matter Experts: What’s the Connection?

    Science.gov (United States)

    Harman, Pamela; Girls Scouts of Northern California, Girl Scouts USA, Astronomical Society of the Pacifica, Univeristy of Arizona, and ARIES Scientific.

    2018-01-01

    Reaching for the Stars: NASA Science for Girl Scouts (Girl Scout Stars) fosters interaction between Girl Scouts and NASA Subject Matter Experts (SMEs), disseminates NASA STEM education-related resources, and engages Girl Scouts in NASA science and programs through space science badges and summer camps.A space science badge is in development for each of the six levels of Girl Scouts: Daisies, Grades K – 1; Brownies, Grades 2 -3; Juniors, Grades 4 -5; Cadettes, Grades 6 -8; Seniors, Grades 9 -10; and Ambassadors, Grades 11 -12. Indirectly, SMEs will reach tens of thousands of girls through the badges. SETI Institute SMEs Institute and SME Co-Is located at ARIES Scientific, Astronomical Society of the Pacific, University of Arizona, and Girl Scouts of Northern California developed and modified astronomy activities for the Girl Scouts USA badge writers to finesse into the Girl Scout formats. Revisions are reviewed by SMEs for accuracy. Each badge includes a step option that encourages girls to connect with SMEs, and recommendations for volunteers.A total of 127 girls from 31 states and the District of Columbia attendedTotal Eclipse Destination Camps at three locations. SMEs led activities and tours, inspiring girls to consider STEM careers. University of Arizona (U of A) SMEs lead Astronomy Camp for Volunteers, enabling volunteers to lead and inspire Girl Scouts in their respective Girl Scout Councils. A Destination Camp for Girl Scouts was also held at U of A. Girls experience authentic astronomy, learning how to collect and analyze data.Eleven teams comprised of two Girl Scouts, a volunteer or Council Staff, and an amateur astronomer attended Astronomy Club Camp, held at NASA GSFC. SMEs delivered science content. The girls will lead the formation of astronomy clubs in their councils, and will train their successors. SMEs will present and coach the clubs during monthly webinars.This presentation will highlight success and discuss lessons learned that are applicable

  11. An Inaugural Girl Scout Destinations Astronomy Camp

    Science.gov (United States)

    Lebofsky, Larry A.; McCarthy, Donald W.; Wright, Joe; Wright, Rita; Mace, Mikayla; Floyd, Charmayne

    2017-10-01

    The University of Arizona (UA) conducted its first teenage Girl Scout Destinations Astronomy Camp. This program was preceded by 24 Leadership Workshops for Adult Girl Scout Leaders, initially supported by EPO funding from NIRCam for JWST. For five days in late June, 24 girls (ages 13-17 years) attended from 16 states. The Camp was led by UA astronomers and long-term educators. Representing Girl Scouts of the USA (GSUSA) were a husband/wife amateur astronomer team who are SOFIA Airborne Astronomy and NASA Solar System Ambassadors. Other leaders included a Stanford undergraduate engineering student who is a lifelong Girl Scout and Gold Award recipient and a recent UA Master’s degree science journalist. The Camp is a residential, hands-on “immersion” adventure in scientific exploration using telescopes in southern Arizona’s Catalina Mountains near Tucson. Under uniquely dark skies girls become real astronomers, operating telescopes (small and large) and associated technologies, interacting with scientists, obtaining images and quantitative data, investigating their own questions, and most importantly having fun actually doing science and building observing equipment. Girls achieve a basic understanding of celestial objects, how and why they move, and their historical significance, leading to an authentic understanding of science, research, and engineering. Girls can lead these activities back home in their own troops and councils, encouraging others to consider STEM field careers. These programs are supported by a 5-year NASA Collaborative Agreement, Reaching for the Stars: NASA Science for Girl Scouts (www.seti.org/GirlScoutStars), through the SETI Institute in collaboration with the UA, GSUSA, Girl Scouts of Northern California, the Astronomical Society of the Pacific, and Aries Scientific, Inc. The Girl Scout Destinations Astronomy Camp aligns with the GSUSA Journey: It’s Your Planet-Love It! and introduces the girls to some of the activities being

  12. Girl Scout Camps and Badges: Engaging Girls in NASA Science

    Science.gov (United States)

    Harman, P. K.; DeVore, E. K.

    2017-12-01

    Reaching for the Stars: NASA Science for Girl Scouts (Girl Scout Stars) disseminates NASA STEM education-related resources, fosters interaction between Girl Scouts and NASA Subject Matter Experts (SMEs), and engages Girl Scouts in NASA science and programs through space science badges and summer camps. A space science badge is in development for each of the six levels of Girl Scouts: Daisies, Grades K - 1; Brownies, Grades 2 -3; Juniors, Grades 4 -5; Cadettes, Grades 6 -8; Seniors, Grades 9 -10: and Ambassadors, Grades 11 -12. Daisy badge will be accomplished by following three steps with two choices each. Brownie to Ambassador badges will be awarded by completing five steps with three choices for each. The badges are interwoven with science activities, role models (SMEs), and steps that lead girls to explore NASA missions. External evaluators monitor three rounds of field-testing and deliver formative assessment reports. Badges will be released in Fall of 2018 and 2019. Girl Scout Stars supports two unique camp experiences. The University of Arizona holds an Astronomy Destination, a travel and immersion adventure for individual girls ages 13 and older, which offers dark skies and science exploration using telescopes, and interacting with SMEs. Girls lean about motion of celestial objects and become astronomers. Councils send teams of two girls, a council representative and an amateur astronomer to Astronomy Camp at Goddard Space Flight Center. The teams were immersed in science content and activities, and a star party; and began to plan their new Girl Scout Astronomy Clubs. The girls will lead the clubs, aided by the council and amateur astronomer. Camps are evaluated by the Girl Scouts Research Institute. In Girl Scouting, girls discover their skills, talents and what they care about; connect with other Girl Scouts and people in their community; and take action to change the world. This is called the Girl Scout Leadership Experience. With girl-led, hands on

  13. Developmental Trajectories of Youth Character: A Five-Wave Longitudinal Study of Cub Scouts and Non-Scout Boys.

    Science.gov (United States)

    Wang, Jun; Ferris, Kaitlyn A; Hershberg, Rachel M; Lerner, Richard M

    2015-12-01

    Youth development programs, such as the Boy Scouts of America, aim to develop positive attributes in youth (e.g., character virtues, prosocial behaviors, and positive civic actions), which are necessary for individuals and societies to flourish. However, few developmental studies have focused on how specific positive attributes develop through participation in programs such as the Boy Scouts of America. As part of the Character and Merit Project, this article examined the developmental trajectories of character and other positive attributes, which are of focal concern of the Boy Scouts of America and the developmental literature. Data were collected from 1398 Scouts (M = 8.59 years, SD = 1.29 years, Range 6.17-11.92 years) and 325 non-Scout boys (M = 9.06 years, SD = 1.43 years, Range 6.20-11.81 years) over five waves of testing across a two-and-half-year period. Latent growth-curve analyses of self-report survey data examined the developmental trajectories of the attributes. Older youth rated themselves lower than younger participants on helpfulness, reverence, thriftiness, and school performance. However, all youth had moderately high self-ratings on all the attributes. Across waves, Scouts' self-ratings increased significantly for cheerfulness, helpfulness, kindness, obedience, trustworthiness, and hopeful future expectations. Non-Scout boys' self-ratings showed no significant change for any attributes except for a significant decrease in religious reverence among non-Scout boys from religious institutions. We discuss implications for positive youth development and for the role of the Boy Scouts of America programming in character development.

  14. Data Scouting in CMS

    CERN Document Server

    Anderson, Dustin James

    2016-01-01

    In 2011, the CMS collaboration introduced Data Scouting as a way to produce physics results with events that cannot be stored on disk, due to resource limits in the data acquisition and offline infrastructure. The viability of this technique was demonstrated in 2012, when 18 fb$^{-1}$ of collision data at $\\sqrt{s}$ = 8 TeV were collected. The technique is now a standard ingredient of CMS and ATLAS data-taking strategy. In this talk, we present the status of data scouting in CMS and the improvements introduced in 2015 and 2016, which promoted data scouting to a full-fledged, flexible discovery tool for the LHC Run II.

  15. The Stochastic Scouting Problem

    NARCIS (Netherlands)

    Barros, A.I.; Evers, L.

    2012-01-01

    Efficiently scouting talented sports players is of key importance in the commercially oriented sports world. Besides being able to recognize talent, it is important to plan the scouting activities given the available time, in order to maximize the potential for scouting talented players. This

  16. Improving the Tank Scout

    National Research Council Canada - National Science Library

    Burton, R. L

    2006-01-01

    .... While the tank battalions recognize the importance and value of the scout platoon, they are restricted from employing scouts to their full potential due to the platoon's inflexible structure and limited capabilities...

  17. Near Earth Asteroid Scout

    Data.gov (United States)

    National Aeronautics and Space Administration — Near-Earth Asteroid Scout, or NEA Scout, is a 6U CubeSat developed jointly between NASA’s Marshall Space Flight Center and the Jet Propulsion Laboratory. NASA...

  18. National Boy Scout Jamboree

    Science.gov (United States)

    1989-01-01

    This video looks at a NASA sponsored exhibit at the National Boy Scout Jamboree in Fredricksburg, VA. Boy Scouts are shown interacting with NASA researchers and astronauts and touring mockups of Space Station Freedom and Apollo 11. NASA's program to encourage the researchers of tomorrow is detailed.

  19. US Cub Scouts visit CERN

    CERN Multimedia

    2001-01-01

    A group of young American Cub Scouts from Den 10, Pack 130 (based in Geneva) at the Microcosm last Saturday. On their trip to CERN, which included the first Visits Service tour of the ATLAS construction site, the scouts were able to satisfy most of the requirements for the Cub Scout engineering badge. From left to right: Edouard Vincent, Ariel Litke, Alexander Richter, Antoine Vidal de Saint Phalle, Jason Iredale and Daniel Reghelini.

  20. Tolerability of sibutramine during a 6-week treatment period in high-risk patients with cardiovascular disease and/or diabetes: a preliminary analysis of the Sibutramine Cardiovascular Outcomes (SCOUT) Trial

    DEFF Research Database (Denmark)

    Maggioni, A.P.; Caterson, I.; Coutinho, W.

    2008-01-01

    Uncertainties about the cardiovascular safety of sibutramine led to the SCOUT trial that is investigating sibutramine plus weight management in high-risk, overweight/obese patients. A 6-week lead-in period during which all patients received sibutramine permitted an initial assessment...... of tolerability. A total of 10,742 patients received sibutramine and 3.1% of these discontinued due to an adverse event; issues affecting more than 10 patients were drug intolerance, headache, insomnia, nausea, dry mouth, and constipation-, tachycardia-, and hypertension-related events. Serious adverse events......, most commonly associated with the System Organ Class, Cardiac disorders, were reported by 2.7% of patients; however, the majority was not considered sibutramine-related. Adverse events relating to high blood pressure and/or pulse rate, whether reported as adverse events leading to discontinuation...

  1. Cognitive Scout Node for Communication in Disaster Scenarios

    Directory of Open Access Journals (Sweden)

    Rajesh K. Sharma

    2012-01-01

    highly desired to manage unexpected situations that may happen in a disaster scenario. The scout node proposed in this paper is an extended concept based on a powerful CR node in a heterogeneous nodes environment which takes a leading role for highly flexible, fast, and robust establishment of cooperative wireless links in a disaster situation. This node should have two components: one is a passive sensor unit that collects and stores the technical knowledge about the electromagnetic environment in a data processing unit so-called “radio environment map” in the form of a dynamically updated database, and other is an active transceiver unit which can automatically be configured either as a secondary node for opportunistic communication or as a cooperative base station or access point for primary network in emergency communications. Scout solution can be viable by taking advantage of the technologies used by existing radio surveillance systems in the context of CR.

  2. Leadership Workshops for Adult Girl Scout Leaders

    Science.gov (United States)

    Lebofsky, Larry A.; McCarthy, Donald; DeVore, Edna; Harman, Pamela; Reaching Stars Team

    2016-10-01

    This year, the University of Arizona is conducting its first two Leadership Workshops for Girl Scout adult leaders. These workshops are being supported by a five-year NASA Collaborative Agreement, Reaching for the Stars: NASA Science for Girl Scouts (www.seti.org/GirlScoutStars), through the SETI Institute in collaboration with the University of Arizona, Girl Scouts of the USA (GSUSA), the Girl Scouts of Northern California, the Astronomical Society of the Pacific, and Aries Scientific, Inc. These workshops are an outgrowth of Astronomy Camp for Girl Scout Leaders, a 14-year "Train the Trainer" program funded by NASA through the James Webb Space Telescope's Near Infrared Camera (NIRCam) education and outreach team. We are continuing our long-term relationship with all Girl Scout Councils to engage girls and young women not only in science and math education, but also in the astronomical and technological concepts relating to NASA's scientific mission. Our training aligns with the GSUSA Journey: It's Your Planet-Love It! and introduces participants to some of the activities that are being developed by the Girl Scout Stars team for GSUSA's new space science badges for all Girl Scout levels being developed as a part of Reaching for the Stars: NASA Science for Girl Scouts.The workshops include hands-on activities in basic astronomy (night sky, stars, galaxies, optics, telescopes, etc.) as well as some more advanced concepts such as lookback time and the expansion of the Universe. Since the inception of our original Astronomy Camp in 2003, our team has grown to include nearly 280 adult leaders, staff, and volunteers from over 79 Councils in 43 states and the District of Columbia so they can, in turn, teach young women essential concepts in astronomy, the night sky environment, applied math, and engineering. Our workshops model what astronomers do by engaging participants in the process of science inquiry, while equipping adults to host astronomy-related programs with

  3. Scouts behave as streakers in honeybee swarms

    Science.gov (United States)

    Greggers, Uwe; Schöning, Caspar; Degen, Jacqueline; Menzel, Randolf

    2013-08-01

    Harmonic radar tracking was used to record the flights of scout bees during takeoff and initial flight path of two honeybee swarms. One swarm remained intact and performed a full flight to a destination beyond the range of the harmonic radar, while a second swarm disintegrated within the range of the radar and most of the bees returned to the queen. The initial stretch of the full flight is characterized by accelerating speed, whereas the disintegrating swarm flew steadily at low speed. The two scouts in the swarm displaying full flight performed characteristic flight maneuvers. They flew at high speed when traveling in the direction of their destination and slowed down or returned over short stretches at low speed. Scouts in the disintegrating swarm did not exhibit the same kind of characteristic flight performance. Our data support the streaker bee hypothesis proposing that scout bees guide the swarm by traveling at high speed in the direction of the new nest site for short stretches of flight and slowing down when reversing flight direction.

  4. Soil and Water Conservation Activities for Scouts.

    Science.gov (United States)

    Soil Conservation Service (USDA), Washington, DC.

    The purpose of the learning activities outlined in this booklet is to help Scouts understand some conservation principles which hopefully will lead to the development of an attitude of concern for the environment and a commitment to help with the task of using and managing soil, water, and other natural resources for long range needs as well as…

  5. CT scout films: Don't forget to look

    International Nuclear Information System (INIS)

    Emamian, Seyed A.; Dubovsky, Elizabeth C.; Vezina, L. Gilbert; Bulas, Dorothy I.; Carter, William

    2003-01-01

    A lateral scout view of the head is always obtained when performing head computed tomography (CT). It is common knowledge that viewing the lateral scout view may provide additional information. For a variety of reasons, however, a careful review may not be performed routinely. To illustrate the value of the lateral scout view, we present a series of representative cases. Six patients with clinically relevant findings on the scout view. Most of the ancillary findings were in the upper cervical spine/neck, which is typically included on the lateral scout view. Careful evaluation of the scout view of the head CT, including the skull and neck, may yield valuable information, which may not be visualized on the axial CT images. (orig.)

  6. Scout or Cavalry? Optimal Discovery Strategies for GRBs

    International Nuclear Information System (INIS)

    Nemiroff, Robert J.

    2004-01-01

    Many present and past gamma-ray burst (GRB) detectors try to be not only a 'scout', discovering new GRBs, but also the 'cavalry', simultaneously optimizing on-board science return. Recently, however, most GRB science return has moved out from the gamma-ray energy bands where discovery usually occurs. Therefore a future gamma-ray instrument that is only a scout might best optimize future GRB science. Such a scout would specialize solely in the initial discovery of GRBs, determining only those properties that would allow an unambiguous handoff to waiting cavalry instruments. Preliminary general principles of scout design and cadence are discussed. Scouts could implement observing algorithms optimized for finding GRBs with specific attributes of duration, location, or energy. Scout sky-scanning algorithms utilizing a return cadence near to desired durations of short GRBs are suggested as a method of discovering GRBs in the unexplored short duration part of the GRB duration distribution

  7. CT scout films: Don't forget to look.

    Energy Technology Data Exchange (ETDEWEB)

    Emamian, Seyed A.; Dubovsky, Elizabeth C.; Vezina, L. Gilbert; Bulas, Dorothy I. [Department of Diagnostic Imaging and Radiology, Children' s National Medical Center, George Washington University, 111 Michigan Avenue NW, DC 20010, Washington (United States); Carter, William [Department of Radiology, Bethesda Naval Medical Center, Rockville, MD (United States)

    2003-08-01

    A lateral scout view of the head is always obtained when performing head computed tomography (CT). It is common knowledge that viewing the lateral scout view may provide additional information. For a variety of reasons, however, a careful review may not be performed routinely. To illustrate the value of the lateral scout view, we present a series of representative cases. Six patients with clinically relevant findings on the scout view. Most of the ancillary findings were in the upper cervical spine/neck, which is typically included on the lateral scout view. Careful evaluation of the scout view of the head CT, including the skull and neck, may yield valuable information, which may not be visualized on the axial CT images. (orig.)

  8. Evaluating Boy Scout Geology Education, A Pilot Study

    Science.gov (United States)

    Hintz, R. S.; Thomson, B.

    2008-12-01

    This study investigated geology knowledge acquisition by Boy Scouts through use of the Boy Scout Geology Merit Handbook. In this study, boys engaged in hands-on interactive learning following the requirements set forth in the Geology Merit Badge Handbook. The purposes of this study were to determine the amount of geology content knowledge engendered in adolescent males through the use of the Geology Merit Badge Handbook published by the Boy Scouts of America; to determine if single sex, activity oriented, free-choice learning programs can be effective in promoting knowledge development in young males; and to determine if boys participating in the Scouting program believed their participation helped them succeed in school. Members of a local Boy Scout Troop between the ages of 11 and 18 were invited to participate in a Geology Merit Badge program. Boys who did not already possess the badge were allowed to self-select participation. The boys' content knowledge of geology, rocks, and minerals was pre- and post-tested. Boys were interviewed about their school and Scouting experiences; whether they believed their Scouting experiences and work in Merit Badges contributed to their success in school. Contributing educational theories included single-sex education, informal education with free-choice learning, learning styles, hands-on activities, and the social cognitive theory concept of self-efficacy. Boys who completed this study seemed to possess a greater knowledge of geology than they obtained in school. If boys who complete the Boy Scout Geology Merit Badge receive additional geological training, their field experiences and knowledge acquired through this learning experience will be beneficial, and a basis for continued scaffolding of geologic knowledge.

  9. ScoutTM, a portable MCA system

    International Nuclear Information System (INIS)

    Cheng, A.Y.; Ziemba, F.P.; Browning, J.E.; Szluk, N.

    1998-01-01

    Quantrad Sensor's hand-held multichannel analyzer (MCA), the Scout TM , has evolved considerably from the initial licensing from Pacific Northwest Laboratories (operated by Battelle Memorial Institute for the U.S. DOE). The Scout TM has grown into a flexible MCA system with alpha-, gamma-, X-ray and neutron detection capabilities with wide ranging applications. The development philosophy is discussed along with specific examples of design choices in areas such as manufacturability, upgradability, probe interchangability and software user interface. Recently introduced products include: software enhancements, additional probes, customized software and a second generation instrument, the Scout512 TM , that boasts increased capabilities. Future developments are also discussed. (author)

  10. Field applications of the ScoutTM portable MCA

    International Nuclear Information System (INIS)

    Cheng, A.Y.; Ziemba, F.P.; Browning, J.E.

    1998-01-01

    The use of Quantrad Sensor's Scout TM in field type applications is described. The portability of the Scout TM enables the user to obtain more accurate information in the field versus a survey meter. Isotopic identification is possible when ancillary information is combined with built-in software libraries. Data from the Scout TM in remediation at Stanford Linear Accelerator (SLAC), NORM (Naturally Occurring Radioactive Material) measurements in California's Central Valley oil fields, medical isotope identification at nuclear pharmaceutical company and emergency response applications are presented. Additionally, custom software enabled the use of the Scout TM in identification, qualification and detection of Special Nuclear Materials (SNM) in illicit trafficking and portal monitoring applications. (author)

  11. Scout: orbit analysis and hazard assessment for NEOCP objects

    Science.gov (United States)

    Farnocchia, Davide; Chesley, Steven R.; Chamberlin, Alan B.

    2016-10-01

    It typically takes a few days for a newly discovered asteroid to be officially recognized as a real object. During this time, the tentative discovery is published on the Minor Planet Center's Near-Earth Object Confirmation Page (NEOCP) until additional observations confirm that the object is a real asteroid rather than an observational artifact or an artificial object. Also, NEOCP objects could have a limited observability window and yet be scientifically interesting, e.g., radar and lightcurve targets, mini-moons (temporary Earth captures), mission accessible targets, close approachers or even impactors. For instance, the only two asteroids discovered before an impact, 2008 TC3 and 2014 AA, both reached the Earth less than a day after discovery. For these reasons we developed Scout, an automated system that provides an orbital and hazard assessment for NEOCP objects within minutes after the observations are available. Scout's rapid analysis increases the chances of securing the trajectory of interesting NEOCP objects before the ephemeris uncertainty grows too large or the observing geometry becomes unfavorable. The generally short observation arcs, perhaps only a few hours or even less, lead severe degeneracies in the orbit estimation process. To overcome these degeneracies Scout relies on systematic ranging, a technique that derives possible orbits by scanning a grid in the poorly constrained space of topocentric range and range rate, while the plane-of-sky position and motion are directly tied to the recorded observations. This scan allows us to derive a distribution of the possible orbits and in turn identify the NEOCP objects of most interest to prioritize followup efforts. In particular, Scout ranks objects according to the likelihood of an impact, estimates the close approach distance, the Earth-relative minimum orbit intersection distance and v-infinity, and computes scores to identify objects more likely to be an NEO, a km-sized NEO, a Potentially

  12. A group-randomized controlled trial for health promotion in Girl Scouts: healthier troops in a SNAP (Scouting Nutrition & Activity Program).

    Science.gov (United States)

    Rosenkranz, Richard R; Behrens, Timothy K; Dzewaltowski, David A

    2010-02-19

    Girl Scouting may offer a viable channel for health promotion and obesity prevention programs. This study evaluated the effectiveness of an intervention program delivered through Girl Scout Junior troops that was designed to foster healthful troop meeting environments and increase obesity prevention behaviors at home. Seven Girl Scout troops were randomized to intervention (n = 3, with 34 girls) or standard-care control (n = 4, with 42 girls) conditions. Girls ranged in age from 9 to 13 years (mean 10.5 years). Intervention troop leaders were trained to implement policies promoting physical activity (PA) and healthful eating opportunities at troop meetings, and to implement a curriculum promoting obesity-prevention behaviors at home. The primary outcome variable was child body mass index (BMI) z-score. Secondary outcomes included accelerometer-assessed PA levels in troop meetings, direct observations of snack offerings, time spent in physically active meeting content, and leader encouragement of PA and healthful eating. The intervention was delivered with good fidelity, and intervention troops provided greater opportunities for healthful eating and PA (x2 = 210.8, p environments in Girl Scout troop meetings appears feasible on a broader scale. Additional work is needed to bridge health promotion from such settings to other environments if lasting individual-level behavior change and obesity prevention remain targeted outcomes. NCT00949637.

  13. Engendering Children of the Resistance: Models of Gender and Scouting in China, 1919–1937

    Directory of Open Access Journals (Sweden)

    Margaret Mih Tillman

    2014-12-01

    Full Text Available In the 1920s and 1930s, Chinese adapted scouting, which had originally been developed to masculinize British youth as future colonial troops. While Chinese families and teachers valued scouting as a form of outdoor recreation, Chiang Kai-shek and the Guomindang after 1927 connected scouting to preparation for military training. In addition to fostering masculinity among boys, the Chinese Scouting Association also directed Girl Scouts with new models of patriotic girlhood. The Guomindang promoted the distinct femininity of the Girl Scouts and channeled girls’ patriotism into nursing. As China entered World War II, Girl Scouts became significant symbols of patriotism in an increasingly militarized children’s culture. The Guomindang showcased Yang Huimin, a Girl Scout and heroine in the Battle of Sihang Warehouse, as a spokesperson for the Nationalist cause, but it could not fully control her public image.

  14. Pre-procedural scout radiographs are unnecessary for routine pediatric fluoroscopic examinations

    Energy Technology Data Exchange (ETDEWEB)

    Creeden, Sean G.; Rao, Anil G.; Eklund, Meryle J.; Hill, Jeanne G.; Thacker, Paul G. [Medical University of South Carolina, Department of Radiology and Radiological Science, Charleston, SC (United States)

    2017-03-15

    Although practice patterns vary, scout radiographs are often routinely performed with pediatric fluoroscopic studies. However few studies have evaluated their utility in routine pediatric fluoroscopy. To evaluate the value of scout abdomen radiographs in routine barium or water-soluble enema, upper gastrointestinal (GI) series, and voiding cystourethrogram pediatric fluoroscopic procedures. We retrospectively evaluated 723 barium or water-soluble enema, upper GI series, and voiding cystourethrogram fluoroscopic procedures performed at our institution. We assessed patient history and demographics, clinical indication for the examination, prior imaging findings and impressions, scout radiograph findings, additional findings provided by the scout radiograph that were previously unknown, and whether the scout radiograph contributed any findings that significantly changed management. We retrospectively evaluated 723 fluoroscopic studies (368 males and 355 females) in pediatric patients. Of these, 700 (96.8%) had a preliminary scout radiograph. Twenty-three (3.2%) had a same-day radiograph substituted as a scout radiograph. Preliminary scout abdomen radiographs/same-day radiographs showed no new significant findings in 719 (99.4%) studies. New but clinically insignificant findings were seen in 4 (0.6%) studies and included umbilical hernia, inguinal hernia and hip dysplasia. No findings were found on the scout radiographs that would either alter the examination performed or change management with regard to the exam. Pre-procedural scout abdomen radiographs are unnecessary in routine barium and water-soluble enema, upper GI series, and voiding cystourethrogram pediatric fluoroscopic procedures and can be substituted with a spot fluoroscopic last-image hold. (orig.)

  15. Old-fashioned charm and newfangled electronics make today's oil scouts formidable figures

    International Nuclear Information System (INIS)

    Lorenz, A.

    1999-01-01

    A profile of oil scouting, a secretive trade within the petroleum industry, was presented. Scouting began as early as 1949 when, in a fiercely competitive industry, a scout had to gain any information anyway he could regarding a competitor's drilling activity. Scouts were particularly useful when the industry was new because it was profitable to pay a field scout to watch a competitor's well from a hilltop with binoculars. If a scout informed their company that a given lease looked promising, the company would snap up that lease and the scout earned his wages many times over. Today's oil scout is more likely to be an independent consultant than a company employee. Their equipment ranges from devices such as parabolic microphones, wireless transmitters, night vision goggles, de-bugging devices, tools for listening through solid objects, and cell phone monitors. Acquired information can be invaluable and can prevent companies from making expensive mistakes, particularly in take-over situations. Estimates range from 100 to 150 independent scouts in Alberta. 2 figs

  16. Lessons Learned from Custer’s Last Stand for Developing Acquisition Scouts

    Science.gov (United States)

    2017-03-31

    Private, Indian Scout Reynolds, Charles Alexander KIA Guide, Quartermaster Round Wooden Cloud Sioux Private, Indian Scout Running Wolf NP...Arikara Private, Indian Scout White Cloud Arikara Private, Indian Scout White Eagle Arikara Private, Indian Scout White Man Runs Him Crow...American West. Little, Brown, and Company. FM 2-22.3, (2006). Human Intelligence Collector Operations. HQ , Department of the Army, Washington, D.C

  17. Educational Work of the Boy Scouts. Bulletin, 1921, No. 41

    Science.gov (United States)

    Barclay, Lorne W.

    1921-01-01

    Scouting continues to enjoy the cordial endorsement of school men everywhere in the US. More and more those interested are coming to see the enormous possibilities of cooperation between the scout movement and the schools. Many schools now give credit for scout work done outside of the schools. Many more are in hearty sympathy with the program as…

  18. System Engineering Analysis For Improved Scout Business Information Systems

    Energy Technology Data Exchange (ETDEWEB)

    Van Slyke, D. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-01-30

    The project uses system engineering principles to address the need of Boy Scout leaders for an integrated system to facilitate advancement and awards records, leader training and planning for meetings and activities. Existing products to address needs of Scout leaders and relevant stakeholders function to support record keeping and some communication functions but opportunity exists for a better system to fully integrate these functions with training delivery and recording, activity planning along with feedback and information gathering from stakeholders. Key stakeholders for the sytem include Scouts and their families, leaders, training providers, sellers of supplies and awards, content generators and facilities that serve Scout activities. Key performance parameters for the system are protection of personal information, availability of current information, information accuracy and information content that has depth. Implementation concepts considered for the system include (1) owned and operated by Boy Scouts of America, (2) Contracted out to a vendor (3) distributed system that functions with BSA managed interfaces. The selected concept is to contract out to a vendor to maximize the likelihood of successful integration and take advantage of the best technology. Development of requirements considers three key use cases (1) System facilitates planning a hike with training needed satisfied in advance and advancement recording real time (2) Scheduling and documenting in-person training, (3) Family interested in Scouting receives information and can request follow-up. Non-functional requirements are analyzed with the Quality Function Deployment tool. Requirement addressing frequency of backup, compatibility with legacy and new technology, language support, software update are developed to address system reliability and intuitive interface. System functions analyzed include update of activity database, maintenance of advancement status, archive of documents, and

  19. The Control of Sexuality in the Early British Boy Scouts Movement

    Science.gov (United States)

    Pryke, Sam

    2005-01-01

    This article looks at the way in which the early (1907-1922) British Boy Scouts movement attempted to control sexuality through archival examination of the organization's preoccupation with preventing masturbation or, as it was generally referred to, "self abuse". Having briefly outlined the origination and nature of the Scouts, it considers why…

  20. User's operating procedures. Volume 1: Scout project information programs

    Science.gov (United States)

    Harris, C. G.; Harris, D. K.

    1985-01-01

    A review of the user's operating procedures for the Scout Project Automatic Data System, called SPADS is given. SPADS is the result of the past seven years of software development on a Prime minicomputer located at the Scout Project Office. SPADS was developed as a single entry, multiple cross reference data management and information retrieval system for the automation of Project office tasks, including engineering, financial, managerial, and clerical support. The instructions to operate the Scout Project Information programs in data retrieval and file maintenance via the user friendly menu drivers is presented.

  1. Improving the Tank Scout

    National Research Council Canada - National Science Library

    Burton, R. L

    2006-01-01

    Within the Marine Corps' tank battalions is a unique asset that is often improperly employed and not well known within the other components of the Marine Air Ground Task Force (MAGTF): the scout platoon...

  2. Tolerability of sibutramine during a 6-week treatment period in high-risk patients with cardiovascular disease and/or diabetes: a preliminary analysis of the Sibutramine Cardiovascular Outcomes (SCOUT) Trial.

    Science.gov (United States)

    Maggioni, Aldo P; Caterson, Ian; Coutinho, Walmir; Finer, Nick; Gaal, Luc Van; Sharma, Arya M; Torp-Pedersen, Christian; Bacher, Peter; Shepherd, Gillian; Sun, Rui; James, Philip

    2008-11-01

    Uncertainties about the cardiovascular safety of sibutramine led to the SCOUT trial that is investigating sibutramine plus weight management in high-risk, overweight/obese patients. A 6-week lead-in period during which all patients received sibutramine permitted an initial assessment of tolerability. A total of 10,742 patients received sibutramine and 3.1% of these discontinued due to an adverse event; issues affecting more than 10 patients were drug intolerance, headache, insomnia, nausea, dry mouth, and constipation-, tachycardia-, and hypertension-related events. Serious adverse events, most commonly associated with the System Organ Class, Cardiac disorders, were reported by 2.7% of patients; however, the majority was not considered sibutramine-related. Adverse events relating to high blood pressure and/or pulse rate, whether reported as adverse events leading to discontinuation, or serious adverse events were reported by less than 0.2% of patients. No serious or individual events leading to discontinuation occurred in more than 25 patients. There were 15 (0.1%) deaths; 10 were attributed to a cardiovascular cause. Discontinuations for adverse events were lower than anticipated. Serious adverse events generally reflected sibutramine's known pharmacology or were related to cardiac disorders already present in this high-risk population. When compared with epidemiological data, overall mortality rate was low and sibutramine was well tolerated in this mainly off-label population. No new safety issues were detected.

  3. Comparative brain transcriptomic analyses of scouting across distinct behavioural and ecological contexts in honeybees

    Science.gov (United States)

    Liang, Zhengzheng S.; Mattila, Heather R.; Rodriguez-Zas, Sandra L.; Southey, Bruce R.; Seeley, Thomas D.; Robinson, Gene E.

    2014-01-01

    Individual differences in behaviour are often consistent across time and contexts, but it is not clear whether such consistency is reflected at the molecular level. We explored this issue by studying scouting in honeybees in two different behavioural and ecological contexts: finding new sources of floral food resources and finding a new nest site. Brain gene expression profiles in food-source and nest-site scouts showed a significant overlap, despite large expression differences associated with the two different contexts. Class prediction and ‘leave-one-out’ cross-validation analyses revealed that a bee's role as a scout in either context could be predicted with 92.5% success using 89 genes at minimum. We also found that genes related to four neurotransmitter systems were part of a shared brain molecular signature in both types of scouts, and the two types of scouts were more similar for genes related to glutamate and GABA than catecholamine or acetylcholine signalling. These results indicate that consistent behavioural tendencies across different ecological contexts involve a mixture of similarities and differences in brain gene expression. PMID:25355476

  4. A group-randomized controlled trial for health promotion in Girl Scouts: Healthier Troops in a SNAP (Scouting Nutrition & Activity Program

    Directory of Open Access Journals (Sweden)

    Behrens Timothy K

    2010-02-01

    Full Text Available Abstract Background Girl Scouting may offer a viable channel for health promotion and obesity prevention programs. This study evaluated the effectiveness of an intervention program delivered through Girl Scout Junior troops that was designed to foster healthful troop meeting environments and increase obesity prevention behaviors at home. Methods Seven Girl Scout troops were randomized to intervention (n = 3, with 34 girls or standard-care control (n = 4, with 42 girls conditions. Girls ranged in age from 9 to 13 years (mean 10.5 years. Intervention troop leaders were trained to implement policies promoting physical activity (PA and healthful eating opportunities at troop meetings, and to implement a curriculum promoting obesity-prevention behaviors at home. The primary outcome variable was child body mass index (BMI z-score. Secondary outcomes included accelerometer-assessed PA levels in troop meetings, direct observations of snack offerings, time spent in physically active meeting content, and leader encouragement of PA and healthful eating. Results The intervention was delivered with good fidelity, and intervention troops provided greater opportunities for healthful eating and PA (x2 = 210.8, p 2 = 23.46, p 2 = 18.14, p 2 = 9.63, p = .002 compared to control troop leaders. Most effects of the intervention on individual-level variables of girls and parents were not significantly different from the control condition, including the primary outcome of child BMI z-score (F1, 5 = 0.42, p = .544, parent BMI (F1, 5 = 1.58, p = .264, and related behavioral variables. The notable exception was for objectively assessed troop PA, wherein girls in intervention troops accumulated significantly less sedentary (x2 = 6.3, p = .011, significantly more moderate (x2 = 8.2, p = .004, and more moderate-to-vigorous physical activity, (x2 = 18.4, p Conclusions Implementing a health promotion curriculum and supporting policies to provide more healthful environments in

  5. Momentum Management for the NASA Near Earth Asteroid Scout Solar Sail Mission

    Science.gov (United States)

    Heaton, Andrew; Diedrich, Benjamin L.; Orphee, Juan; Stiltner, Brandon; Becker, Christopher

    2017-01-01

    The Momentum Management (MM) system is described for the NASA Near Earth Asteroid Scout (NEA Scout) cubesat solar sail mission. Unlike many solar sail mission proposals that used solar torque as the primary or only attitude control system, NEA Scout uses small reaction wheels (RW) and a reaction control system (RCS) with cold gas thrusters, as described in the abstract "Solar Sail Attitude Control System for Near Earth Asteroid Scout Cubesat Mission." The reaction wheels allow fine pointing and higher rates with low mass actuators to meet the science, communication, and trajectory guidance requirements. The MM system keeps the speed of the wheels within their operating margins using a combination of solar torque and the RCS.

  6. User's operating procedures. Volume 2: Scout project financial analysis program

    Science.gov (United States)

    Harris, C. G.; Haris, D. K.

    1985-01-01

    A review is presented of the user's operating procedures for the Scout Project Automatic Data system, called SPADS. SPADS is the result of the past seven years of software development on a Prime mini-computer located at the Scout Project Office, NASA Langley Research Center, Hampton, Virginia. SPADS was developed as a single entry, multiple cross-reference data management and information retrieval system for the automation of Project office tasks, including engineering, financial, managerial, and clerical support. This volume, two (2) of three (3), provides the instructions to operate the Scout Project Financial Analysis program in data retrieval and file maintenance via the user friendly menu drivers.

  7. Missed Lung Cancers on the Scout View: Do We Look Every Time?

    Directory of Open Access Journals (Sweden)

    Sarfraz Ahmed Nazir

    2013-01-01

    Full Text Available Scout views are digital radiographs obtained to aid planning of the subsequent computed tomography (CT examination. Review of these scout views may provide additional information not demonstrated on the axial images, but such reviews may not necessarily be performed routinely, especially in the context of abdominopelvic CT studies. We illustrate the value of the scout images by presenting a series of representative cases of missed pulmonary neoplasms in five patients who originally underwent such examinations.

  8. Collaborating with Planetaria to Improve Girl Scout's Appreciation of Astronomy

    Science.gov (United States)

    Adams, Mitzi; Phillips, Tony; Whitt, April

    2003-01-01

    We have collaborated with two planetaria, Fernbank Science Center's Jim Cherry planetarium in Atlanta, Georgia and the Von Braun Planetarium in Huntsville, Alabama to enhance the appreciation of various astronomical topics among Girl Scouts. Major events sponsored by our partnership were sleepovers in the planetaria during which we studied the total solar eclipse of June 2001 and observed the Eta Aquarid meteor shower of May 2003. Other events included programs on stellar spectroscopy and space physics. As an added inducement for participation, we have sponsored the production of "pins", which Girl Scouts can earn after satisfying specific requirements. This poster will show samples of the pins, requirements, and online resources for the Girl Scouts.

  9. Art, Boys, and the Boy Scout Movement: Lord Baden-Powell

    Science.gov (United States)

    Chalmers, F. Graeme; Dancer, Andrea A.

    2007-01-01

    Robert Stephenson Smyth Baden-Powell (1857-1941), founder of the Boy Scout Movement in 1907, was a British military hero during the Boer War. Within an ethos and era of empire-building, athleticism, soldier-heroes and the pursuit of "manliness," Baden-Powell valued the arts and adapted his artistic skill to his wartime and Scouting activities. His…

  10. Gradient Scouting in Reversed-Phase HPLC Revisited

    Science.gov (United States)

    Alcazar, A.; Jurado, J. M.; Gonzalez, A. G.

    2011-01-01

    Gradient scouting is the best way to decide the most suitable elution mode in reversed-phase high-performance liquid chromatography (RP-HPLC). A simple rule for this decision involves the evaluation of the ratio [delta]t/t[subscript G] (where [delta]t is the difference in the retention time between the last and the first peak and t[subscript G] is…

  11. Near Earth Asteroid Scout: NASA's Solar Sail Mission to a NEA

    Science.gov (United States)

    Johnson, Les; Lockett, Tiffany

    2017-01-01

    NASA is developing a solar sail propulsion system for use on the Near Earth Asteroid (NEA) Scout reconnaissance mission and laying the groundwork for their use in future deep space science and exploration missions. Solar sails use sunlight to propel vehicles through space by reflecting solar photons from a large, mirror-like sail made of a lightweight, highly reflective material. This continuous photon pressure provides propellantless thrust, allowing for very high Delta V maneuvers on long-duration, deep space exploration. Since reflected light produces thrust, solar sails require no onboard propellant. The Near Earth Asteroid (NEA) Scout mission, funded by NASA's Advanced Exploration Systems Program and managed by NASA MSFC, will use the sail as primary propulsion allowing it to survey and image Asteroid 1991VG and, potentially, other NEA's of interest for possible future human exploration. NEA Scout uses a 6U cubesat (to be provided by NASA's Jet Propulsion Laboratory), an 86 m(exp. 2) solar sail and will weigh less than 12 kilograms. NEA Scout will be launched on the first flight of the Space Launch System in 2018. The solar sail for NEA Scout will be based on the technology developed and flown by the NASA NanoSail-D and The Planetary Society's Lightsail-A. Four approximately 7 m stainless steel booms wrapped on two spools (two overlapping booms per spool) will be motor deployed and pull the sail from its stowed volume. The sail material is an aluminized polyimide approximately 2.5 microns thick. As the technology matures, solar sails will increasingly be used to enable science and exploration missions that are currently impossible or prohibitively expensive using traditional chemical and electric propulsion systems. This paper will summarize the status of the NEA Scout mission and solar sail technology in general.

  12. Temperature-Driven Shape Changes of the Near Earth Asteroid Scout Solar Sail

    Science.gov (United States)

    Stohlman, Olive R.; Loper, Erik R.; Lockett, Tiffany E.

    2017-01-01

    Near Earth Asteroid Scout (NEA Scout) is a NASA deep space Cubesat, scheduled to launch on the Exploration Mission 1 flight of the Space Launch System. NEA Scout will use a deployable solar sail as its primary propulsion system. The sail is a square membrane supported by rigid metallic tapespring booms, and analysis predicts that these booms will experience substantial thermal warping if they are exposed to direct sunlight in the space environment. NASA has conducted sunspot chamber experiments to confirm the thermal distortion of this class of booms, demonstrating tip displacement of between 20 and 50 centimeters in a 4-meter boom. The distortion behavior of the boom is complex and demonstrates an application for advanced thermal-structural analysis. The needs of the NEA Scout project were supported by changing the solar sail design to keep the booms shaded during use of the solar sail, and an additional experiment in the sunspot chamber is presented in support of this solution.

  13. Scout Rover Applications for Forward Acquisition of Soil and Terrain Data

    Science.gov (United States)

    Sonsalla, R.; Ahmed, M.; Fritsche, M.; Akpo, J.; Voegele, T.

    2014-04-01

    As opposed to the present mars exploration missions future mission concepts ask for a fast and safe traverse through vast and varied expanses of terrain. As seen during the Mars Exploration Rover (MER) mission the rovers suffered a lack of detailed soil and terrain information which caused Spirit to get permanently stuck in soft soil. The goal of the FASTER1 EU-FP7 project is to improve the mission safety and the effective traverse speed for planetary rover exploration by determining the traversability of the terrain and lowering the risk to enter hazardous areas. To achieve these goals, a scout rover will be used for soil and terrain sensing ahead of the main rover. This paper describes a highly mobile, and versatile micro scout rover that is used for soil and terrain sensing and is able to co-operate with a primary rover as part of the FASTER approach. The general reference mission idea and concept is addressed within this paper along with top-level requirements derived from the proposed ESA/NASA Mars Sample Return mission (MSR) [4]. Following the mission concept and requirements [3], a concept study for scout rover design and operations has been performed [5]. Based on this study the baseline for the Coyote II rover was designed and built as shown in Figure 1. Coyote II is equipped with a novel locomotion concept, providing high all terrain mobility and allowing to perform side-to-side steering maneuvers which reduce the soil disturbance as compared to common skid steering [6]. The rover serves as test platform for various scout rover application tests ranging from locomotion testing to dual rover operations. From the lessons learned from Coyote II and for an enhanced design, a second generation rover (namely Coyote III) as shown in Figure 2 is being built. This rover serves as scout rover platform for the envisaged FASTER proof of concept field trials. The rover design is based on the test results gained by the Coyote II trials. Coyote III is equipped with two

  14. Lactate versus pH levels in fetal scalp blood during labor--using the Lactate Scout System

    DEFF Research Database (Denmark)

    Lundin, Ingeborg Christina Rørbye; Perslev, Anette; Nickelsen, Carsten Nahne Amtoft

    2016-01-01

    OBJECTIVE: To assess if lactate measured with the Scout Lactate System is a reliable alternative to pH in intrapartum monitoring of the fetus. METHODS: A prospective study analyzing (1) the correlation between scalp lactate measured by the Scout Lactate System and the Automatic Blood Laboratory (...

  15. Computed tomography scout views vs. conventional radiography in body-packers – Delineation of body-packs and radiation dose in a porcine model

    Energy Technology Data Exchange (ETDEWEB)

    Ziegeler, Edvard, E-mail: edvard.ziegeler@campus.lmu.de [Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, Nussbaumstraße 20, 80336 Munich (Germany); Grimm, Jochen M., E-mail: jochen.grimm@med.lmu.de [Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, Nussbaumstraße 20, 80336 Munich (Germany); Wirth, Stefan, E-mail: tefan.wirth@med.lmu.de [Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, Nussbaumstraße 20, 80336 Munich (Germany); Uhl, Michael, E-mail: michael.uhl@polizei.bayern.de [Bavarian State Criminal Police Office, Maillingerstrasse 15, 80636 Munich (Germany); Reiser, Maximilian F., E-mail: Maximilian.Reiser@med.lmu.de [Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, Nussbaumstraße 20, 80336 Munich (Germany); Scherr, Michael K., E-mail: Michael.Scherr@med.lmu.de [Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, Nussbaumstraße 20, 80336 Munich (Germany)

    2012-12-15

    Objective: To compare abdominal computed tomography (CT) scout views with conventional radiography regarding radiation dose and delineation of drug packages in a porcine body-packer model. Materials and methods: Nine samples of illicit drugs packed in ovoid plastic containers were consecutively placed in the rectum of a 121.5 kg pig cadaver. Antero-posterior and lateral scout views were obtained at 120 kVp and 80 mA, 150 mA and 200 mA, respectively, using a 64-row MDCT. Scout views were compared with conventional abdominal antero-posterior radiographs (77 kV and 106 ± 13 mAs). Visibility of three body pack characteristics (wrapping, content, shape) was rated independently by two radiologists and summarized to a delineation score ranging from 0 to 9 with a score ≥6 representing sufficient delineation. Mean delineation scores were calculated for each conventional radiography and single plane scout view separately and for a combined rating of antero-posterior and lateral scout views. Results: Even the lowest single plane scout view delineation score (5.3 ± 2.0 for 80 mA lateral; 0.4 mSv; sensitivity = 44%) was significantly higher than for conventional radiographs (3.1 ± 2.5, p < 0.001; 2.4 ± 0.3 mSv; sensitivity = 11%). Combined reading of antero-posterior and lateral scout views 80 mA yielded sufficient delineation (6.2 ± 1.4; 0.8 mSv; sensitivity = 56%). Conclusions: All CT scout views showed significantly better delineation ratings and sensitivity than conventional radiographs. Scout views in two planes at 80 mA provided a sufficient level of delineation and a sensitivity five times higher than conventional radiography at less than one third of the radiation dose. In case of diagnostic insecurity, CT can be performed without additional logistical effort.

  16. CT dose modulation using automatic exposure control in whole-body PET/CT: effects of scout imaging direction and arm positioning.

    Science.gov (United States)

    Inoue, Yusuke; Nagahara, Kazunori; Kudo, Hiroko; Itoh, Hiroyasu

    2018-01-01

    Automatic exposure control (AEC) modulates tube current and consequently X-ray exposure in CT. We investigated the behavior of AEC systems in whole-body PET/CT. CT images of a whole-body phantom were acquired using AEC on two scanners from different manufactures. The effects of scout imaging direction and arm positioning on dose modulation were evaluated. Image noise was assessed in the chest and upper abdomen. On one scanner, AEC using two scout images in the posteroanterior (PA) and lateral (Lat) directions provided relatively constant image noise along the z-axis with the arms at the sides. Raising the arms increased tube current in the head and neck and decreased it in the body trunk. Image noise increased in the upper abdomen, suggesting excessive reduction in radiation exposure. AEC using the PA scout alone strikingly increased tube current and reduced image noise in the shoulder. Raising the arms did not substantially influence dose modulation and decreased noise in the abdomen. On the other scanner, AEC using the PA scout alone or Lat scout alone resulted in similar dose modulation. Raising the arms increased tube current in the head and neck and decreased it in the trunk. Image noise was higher in the upper abdomen than in the middle and lower chest, and was not influenced by arm positioning. CT dose modulation using AEC may vary greatly depending on scout direction. Raising the arms tended to decrease radiation exposure; however, the effect depends on scout direction and the AEC system.

  17. Scouts in Contact: Tactical Vignettes for Cavalry Leaders

    Science.gov (United States)

    2016-12-01

    Decision - Making Processes Analytical Decision Making . The classical model of decision making is a rational and systematic process of analysis based on a...senior scout are the real measures of effectiveness. Commanders should allow and reward trial and error. If a leader makes a decision that causes...professional certification from the squadron commander on their ability to make competent and fast decisions , grounded in thorough understanding of the

  18. SU-E-T-431: Feasiblity of Using CT Scout Images for 2D LDR Brachytherpay Planning

    Energy Technology Data Exchange (ETDEWEB)

    Ha, J; Weaver, R [LAC+USC Medical Center, Los Angeles, CA, M. Mariscal (United States)

    2015-06-15

    Purpose: i) To show the feasibility of using CT scout images for 2D low-dose rate brachytherapy planning with BrachyVision (version 10.4); ii) to show their advantages and disadvantages over DRRs. Methods: A phantom was constructed to house a Fletcher-Suite applicator. The phantom is made of Styrofoam with metal BBs positioned at well-defined separations. These markers are used to assess the image distortion in the scout images. Unlike DRRs, scout images are distorted only in the direction normal to the couch direction; therefore, they needed to be scaled unidirectionally prior to importing into BrachyVision. In addition to confirming the scaling is performed correctly by measuring distances between well-positioned BB, we also compare a LDR plan using scout images to a 3D CT-based plan. Results: There is no distortion of the image along the couch direction due to the collimation of the CT scanner. The distortion in the transverse plane can be corrected by multiplying by the ratio of distances between source-to-isocenter and source-to-detector. The results show the distance separations between BBs as measured in scout images and by a caliber are within a few millimeters. Dosimetrically, the difference between the dose rates to points A and B based on scout images and on 3D CT are less than a few percents. The accuracy can be improved by correcting for the distortion on the transverse plane. Conclusion: It is possible to use CT scout images for 2D planning in BrachyVision. This is an advantage because scout images have no metal artifacts often present in CT images or DRRs. Another advantage is the lack of distortion in the couch direction. One major disadvantage is that the image distortion due to beam divergence can be large. This is due to the inherent short distance between source-to-isocenter and source-to-detector on a CT scanner.

  19. Lessons for Interstellar Travel from the G&C Design of the NEA Scout Solar Sail Mission

    Science.gov (United States)

    Heaton, Andrew; Diedrich, Benjamin

    2017-01-01

    NASA is developing the Near Earth Asteroid (NEA) Scout mission that will use a solar sail to travel to an asteroid where it will perform a slow flyby to acquire science imagery. A guidance and control system was developed to meet the science and trajectory requirements. The NEA Scout design process can be applied to an interstellar or precursor mission that uses a beam-propelled sail. The scientific objectives are met by accurately targeting the destination trajectory position and velocity. The destination is targeted by understanding the force on the sail from the beam (or sunlight in the case of NEA Scout) over the duration of the thrust maneuver. The propulsive maneuver is maintained by accurate understanding of the torque on the sail, which is a function of sail shape, optical properties, and mass properties, all of which apply to NEA Scout and beam propelled sails. NEA Scout uses active control of the sail attitude while trimming the solar torque, which could be used on a beamed propulsion sail if necessary. The biggest difference is that NEA Scout can correct for uncertainties in sail thrust modeling, spacecraft orbit, and target orbit throughout the flight to the target, while beamed propulsion needs accurate operation for the short duration of the beamed propulsion maneuver, making accurate understanding of the sail thrust and orbits much more critical.

  20. Product mix of recreational tourism in the Balkan scout center

    Directory of Open Access Journals (Sweden)

    Kocevski Miloš

    2013-01-01

    Full Text Available The subject of research is tourist offer of a camp which would satisfy the needs of tourists who want an active recreation, with changeable and attractive facilities in the Balkan Scout Center (BSC of Jovac. The goal is to define a model for recreational tourism product mix of the Balkan Scout Center, based on the analysis and evaluation of the elements of supply and identifying the demand for a certain program content. The research was conducted from April to August 2012, as a part of activities implemented in BSC events: Easter camp, Summer camp and Volunteer camp. The sample consisted of 100 visitors (respondents; the administered instrument was a specifically designed questionnaire and the methods on which the analysis of the modeling was based were: frequency of occurrence, comparative analysis (Benchmarking, SWOT and PEST. The research results confirm the existence of necessary resources for the implementation of the contents in the field of recreational tourism in the BSC, and the possibility of implementation of the product mix that includes day trips and a variety of outdoor recreational activities.

  1. Scout-view assisted interior micro-CT

    International Nuclear Information System (INIS)

    Sharma, Kriti Sen; Narayanan, Shree; Agah, Masoud; Holzner, Christian; Vasilescu, Dragoş M; Jin, Xin; Hoffman, Eric A; Yu, Hengyong; Wang, Ge

    2013-01-01

    Micro computed tomography (micro-CT) is a widely-used imaging technique. A challenge of micro-CT is to quantitatively reconstruct a sample larger than the field-of-view (FOV) of the detector. This scenario is characterized by truncated projections and associated image artifacts. However, for such truncated scans, a low resolution scout scan with an increased FOV is frequently acquired so as to position the sample properly. This study shows that the otherwise discarded scout scans can provide sufficient additional information to uniquely and stably reconstruct the interior region of interest. Two interior reconstruction methods are designed to utilize the multi-resolution data without significant computational overhead. While most previous studies used numerically truncated global projections as interior data, this study uses truly hybrid scans where global and interior scans were carried out at different resolutions. Additionally, owing to the lack of standard interior micro-CT phantoms, we designed and fabricated novel interior micro-CT phantoms for this study to provide means of validation for our algorithms. Finally, two characteristic samples from separate studies were scanned to show the effect of our reconstructions. The presented methods show significant improvements over existing reconstruction algorithms. (paper)

  2. Social Talent Scouting: A New Opportunity for the Identification of Football Players?

    Directory of Open Access Journals (Sweden)

    Radicchi Elena

    2016-06-01

    Full Text Available This paper investigates the diffusion of digital technologies within the football talent scouting process. A qualitative exploration based on open discussions and unstructured interviews with professionals involved in the football system (coaches, scouts, players’ agents, etc. provides insights about how new technologies are used for recruiting athletes. The findings, which are mainly in the context of Italian football, indicate a cultural and generational gap in the use of new digital tools that creates a mismatch between young promising athletes (demand side and “senior” team professionals (supply side.

  3. Big Explosions, Strong Gravity: Making Girl Scouts ACEs of Space through Chandra Outreach

    Science.gov (United States)

    Hornschemeier, A. E.; Lochner, J. C.; Ganguly, R.; Feaga, L. M.; Ford, K. E. S.

    2005-12-01

    Thanks to two years of Chandra E/PO funding we have carried out a number of successful activities with the Girl Scouts of Central Maryland, focusing on girls in the 11-17 year age range. Our reasons for targeting this age range include the general decline in interest in math and science that occurs at or after children reach this critical age (meaning that we reach them early enough to have a positive effect). We initially target girls due to their underrepresentation in science, but the actitivities are all gender-neutral and highly adaptable to other groups. The program includes two components, in collaboration with Girl Scouts of Central Maryland. The first component is a well-established one-day Girl Scout patch activity entitled Big Explosions and Strong Gravity (BESG) where the girls earn a patch for their badge sash. The four BESG activities, mostly adapted from existing E/PO material, are available on the World Wide Web for use by others. The activities cover the electromagnetic spectrum as a tool for astronomy, the cosmic abundance of the elements and the supernova origin of many of the elements, black holes and their detection, and supernova explosions/stellar evolution. Thus far approximately 200 girls and their parents have participated in BESG and it has now become part of the council culture. The second activity is new and is part of the relatively new Girl Scout Studio 2B program, which is a girl-led program for the 11-17 year age range. Based on several meetings with small groups of girls and adults, we have formed a Studio 2B "club" called the ACE of Space Club (Astronomical Cosmic Exploration). We'll describe our experiences interacting with the Girl Scouts in this girl-led program.

  4. Medical Services at an International Summer Camp Event Under Hot and Humid Conditions: Experiences From the 23rd World Scout Jamboree, Japan.

    Science.gov (United States)

    Watanabe, Takemasa; Mizutani, Keiji; Iwai, Toshiyasu; Nakashima, Hiroshi

    2018-06-01

    The 23rd World Scout Jamboree (WSJ) was a 10-day summer camp held in Japan in 2015 under hot and humid conditions. The attendees comprised 33,628 people from 155 countries and territories. The aim of this study was to examine the provision of medical services under such conditions and to identify preventive factors for major diseases among long-term campers. Data were obtained from WSJ medical center records and examined to clarify the effects of age, sex, and period on visit frequencies and rates. Medical records from 3215 patients were examined. Daytime temperatures were 31.5±3.2°C and relative humidity was 61±13% (mean±SD). The initial visit rates among scouts and adults were 72.2 and 77.2 per 1000 persons, respectively. No significant age difference was observed in the initial visit rate; however, it was significantly higher among female patients than male patients. Significant differences were also seen in the adjusted odds ratios by age, sex, and period for disease distributions of initial visit frequencies. In addition, a higher initial visit frequency for heat strain-related diseases was seen among the scouts. Initial visit frequencies for heatstroke and/or dehydration increased just after opening day and persisted until closing day. Our findings suggest the importance of taking effective countermeasures against heat strain, fatigue, and unsanitary conditions at the WSJ. Medical services staff should take attendees' age, sex, and period into consideration to prevent heat strain-related diseases during such camps under hot and humid conditions. Copyright © 2018 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

  5. 78 FR 38452 - Price for the 2013 Girl Scouts of the USA Young Collector Set

    Science.gov (United States)

    2013-06-26

    ... DEPARTMENT OF THE TREASURY United States Mint Price for the 2013 Girl Scouts of the USA Young Collector Set AGENCY: United States Mint, Department of the Treasury. ACTION: Notice. SUMMARY: The United States Mint is announcing a price of $54.95 for the 2013 Girl Scouts of the USA Young Collector Set. FOR...

  6. Effects of a behaviour change intervention for Girl Scouts on child and parent energy-saving behaviours

    Science.gov (United States)

    Boudet, Hilary; Ardoin, Nicole M.; Flora, June; Armel, K. Carrie; Desai, Manisha; Robinson, Thomas N.

    2016-08-01

    Energy education programmes for children are hypothesized to have great potential to save energy. Such interventions are often assumed to impact child and family behaviours. Here, using a cluster-randomized controlled trial with 30 Girl Scout troops in Northern California, we assess the efficacy of two social cognitive theory-based interventions focused on residential and food-and-transportation energy-related behaviours of Girl Scouts and their families. We show that Girl Scouts and parents in troops randomly assigned to the residential energy intervention significantly increased their self-reported residential energy-saving behaviours immediately following the intervention and after more than seven months of follow-up, compared with controls. Girl Scouts in troops randomly assigned to the food-and-transportation energy intervention significantly increased their self-reported food-and-transportation energy-saving behaviours immediately following the intervention, compared with controls, but not at follow-up. The results demonstrate that theory-based, child-focused energy interventions have the potential to increase energy-saving behaviours among both children and their parents.

  7. Scout house in Koeniz - Refurbishment of the heating system; Pfadiheim Weiermatt, Sanierung Waermeversorgung - Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Messerli, A. [Neuenschwander - Neutair AG, Berne (Switzerland); Jenni, H. [Heimverein Falkenstein, Koeniz (Switzerland)

    2004-07-01

    This final report for the Swiss Federal Office of Energy (SFOE) presents the results of a project carried out in Koeniz, Switzerland. The report examines how the energy situation at the local scout house was improved. The work included the refurbishment of the heating system using solar collectors, intelligently controlled heat pumps, a photovoltaics installation and even solar-powered street lighting. The project, which received a substantial echo from the general public, is described. The scouts were directly involved in the project and, in part, in the construction work. This, according to the authors, enhanced the educational aspect of the project. The report presents details on the various installations and is illustrated with schematics and photos. Also, the results of monitoring and measurements made are presented.

  8. Lessons for Interstellar Travel from the Guidance and Control Design of the Near Earth Asteroid Scout Solar Sail Mission

    Science.gov (United States)

    Diedrich, Benjamin; Heaton, Andrew

    2017-01-01

    NASA is developing the Near Earth Asteroid (NEA) Scout mission that will use a solar sail to travel to an asteroid where it will perform a slow flyby to acquire science imagery. A guidance and control system was developed to meet the science and trajectory requirements. The NEA Scout design process can be applied to an interstellar or precursor mission that uses a beam propelled sail. The scientific objectives are met by accurately targeting the destination trajectory position and velocity. The destination is targeted by understanding the force on the sail from the beam (or sunlight in the case of NEA Scout) over the duration of the thrust maneuver. The propulsive maneuver is maintained by accurate understanding of the torque on the sail, which is a function of sail shape, optical properties, and mass properties, all of which apply to NEA Scout and beam propelled sails. NEA Scout uses active control of the sail attitude while trimming the solar torque, which could be used on a beamed propulsion sail if necessary. The biggest difference is that NEA Scout can correct for uncertainties in sail thrust modeling, spacecraft orbit, and target orbit throughout the flight to the target, while beamed propulsion needs accurate operation for the short duration of the beamed propulsion maneuver, making accurate understanding of the sail thrust and orbits much more critical.

  9. Being Prepared: The Application of Character Building and the Beginning of the Boy Scouts of America.

    Science.gov (United States)

    Phelps, Richard

    The beginnings of the Boy Scouts are traced, with particular emphasis on ideological foundation, social reform objectives of the founders (Sir Robert Baden-Powell, Daniel Carter Beard, and Ernest Thompson) and its relationship to other reform movements of the Progressive Era. The philosophical base of scouting is characterized as: 1) a…

  10. Be(ing) prepared: Guide and Scout participation, childhood social position and mental health at age 50-a prospective birth cohort study.

    Science.gov (United States)

    Dibben, Chris; Playford, Chris; Mitchell, Richard

    2017-03-01

    Mental health is a major concern in many countries. We explore whether youth participation in the Scouts and Guides could protect mental health in later life and in particular whether it might reduce inequalities in mental health associated with early life socioeconomic position. Using the 1958 birth cohort National Child Development Study, we tested whether Scouts-Guide attendance was associated with mental health (SF-36, Mental Health Index (MHI-5)) controlling for childhood risk factors and interacted with social class. Of the 9603 cohort members, 28% had participated in the Scouts-Guides. The average MHI-5 score was 74.8 (SD 18.2) at age 50. After adjustment, for potential childhood confounders, participation in Scouts-Guides was associated with a better MHI-5 score of 2.22 (CI 1.32 to 3.08). Among those who had not been a Scout-Guide, there was a gradient in mental health at age 50 by childhood social position, adjusting for other childhood risk factors. This gradient was absent among those who had been a Scout-Guide. Scout-Guides had an 18% lower odds of an MHI-5 score indicative of mood or anxiety disorder. The findings appeared robust to various tests for residual confounding. Participation in Guides or Scouts was associated with better mental health and narrower mental health inequalities, at age 50. This suggests that youth programmes that support resilience and social mobility through developing the potential for continued progressive self-education, 'soft' non-cognitive skills, self-reliance, collaboration and activities in natural environments may be protective of mental health in adulthood. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  11. Brachytherapy reconstruction using orthogonal scout views from the CT

    International Nuclear Information System (INIS)

    Perez, J.; Lliso, F.; Carmona, V.; Bea, J.; Tormo, A.; Petschen, I.

    1996-01-01

    Introduction: CT assisted brachytherapy planning is demonstrating to have great advantages as external RT planning does. One of the problems we have found in this approach with the conventional gynecological Fletcher applicators is the high amount of artefacts (ovoids with rectal and vessical protections) in the CT slice. We have introduced a reconstruction method based on scout views in order to avoid this problem, allowing us to perform brachytherapy reconstruction completely CT assisted. We use a virtual simulation chain by General Electric Medical Systems. Method and discussion: Two orthogonal scout views (0 and 90 tube positions) are performed. The reconstruction method takes into account the virtual position of the focus and the fact that there is only divergence in the transverse plane. Algorithms developed for sources as well as for reference points localisation (A, B, lymphatic Fletcher trapezoid, pelvic wall, etc.) are presented. This method has the following practical advantages: the porte-cassette is not necessary, the image quality can be improved (it is very helpful in pelvic lateral views that are critical in conventional radiographs), the total time to get the data is smaller than for conventional radiographs (reduction of patient motion effects) and problems that appear in CT-slice based reconstruction in the case of strongly curved intrauterine applicators are avoided. Even though the resolution is smaller than in conventional radiographs it is good enough for brachytherapy. Regarding the CT planning this method presents the interesting feature that the co-ordinate system is the same for the reconstruction process that for the CT-slices set. As the application can be reconstructed from scout views and the doses can be evaluated on CT slices it is easier to correlate the dose values obtained for the traditional points with those provided by the CT information

  12. The Near Earth Object (NEO) Scout Spacecraft: A Low-cost Approach to In-situ Characterization of the NEO Population

    Science.gov (United States)

    Woeppel, Eric A.; Balsamo, James M.; Fischer, Karl J.; East, Matthew J.; Styborski, Jeremy A.; Roche, Christopher A.; Ott, Mackenzie D.; Scorza, Matthew J.; Doherty, Christopher D.; Trovato, Andrew J.; hide

    2014-01-01

    This paper describes a microsatellite spacecraft with supporting mission profile and architecture, designed to enable preliminary in-situ characterization of a significant number of Near Earth Objects (NEOs) at reasonably low cost. The spacecraft will be referred to as the NEO-Scout. NEO-Scout spacecraft are to be placed in Geosynchronous Equatorial Orbit (GEO), cis-lunar space, or on earth escape trajectories as secondary payloads on launch vehicles headed for GEO or beyond, and will begin their mission after deployment from the launcher. A distinguishing key feature of the NEO-Scout system is to design the spacecraft and mission timeline so as to enable rendezvous with and landing on the target NEO during NEO close approach (the Earth-Moon system using low-thrust/high-impulse propulsion systems. Mission durations are on the order 100 to 400 days. Mission feasibility and preliminary design analysis are presented, along with detailed trajectory calculations.

  13. Evaluation Models of Some Morphological Characteristcs for Talent Scouting in Sport

    OpenAIRE

    Rogulj, Nenad; Papić, Vladan; Čavala, Marijana

    2009-01-01

    In this paper, for the purpose of expert system evaluation within the scientific project »Talent scouting in sport«, two methodological approaches for recognizing an athlete’s morphological compatibility for various sports has been presented, evaluated and compared. First approach is based on the fuzzy logic and expert opinion about compatibility of proposed hypothetical morphological models for 14 different sports which are part of the expert system. Second approach is based on determining t...

  14. Effects of the Boy Scouts of America Personal Fitness Merit Badge on Cardio-Metabolic Risk, Health Related Fitness and Physical Activity in Adolescent Boys.

    Science.gov (United States)

    Maxwell, Justin; Burns, Ryan D; Brusseau, Timothy A

    2017-01-01

    A growing number of adolescents are more sedentary and have fewer formal opportunities to participate in physical activity. With the mounting evidence that sedentary time has a negative impact on cardiometabolic profiles, health related fitness and physical activity, there is a pressing need to find an affordable adolescent physical activity intervention. One possible intervention that has been overlooked in the past is Boy Scouts of America. There are nearly 900,000 adolescent boys who participate in Boy Scouts in the United States. The purpose of this research study was to evaluate the effect of the Personal Fitness merit badge system on physical activity, health-related fitness, and cardio-metabolic blood profiles in Boy Scouts 11-17 years of age. Participants were fourteen (N = 14) Boy Scouts from the Great Salt Lake Council of the Boy Scouts of America who earned their Personal Fitness merit badge. Classes were held in the Spring of 2016 where boys received the information needed to obtain the merit badge and data were collected. Results from the related-samples Wilcoxon signed rank test showed that the median of differences between VO 2 peak pre-test and post-test scores were statistically significant ( p = 0.004). However, it also showed that the differences between the Pre-MetS (metabolic syndrome) and Post-MetS scores (p = 0.917), average steps taken per day ( p = 0.317), and BMI ( p = 0.419) were not statistically significant. In conclusion, the merit badge program had a positive impact on cardiovascular endurance, suggesting this program has potential to improve cardiovascular fitness and should be considered for boys participating in Boy Scouts.

  15. Seeding Social Norms about Energy Conservation among Girl Scouts

    Science.gov (United States)

    Bernstein, Debra; Puttick, Gillian

    2014-01-01

    Three studies examined whether a social norm message (SNM) to Girl Scouts who had completed an energy conservation program would impact behavior and attitudes. Studies 1 and 2 were conducted with girls recently completing the program, study 3 was conducted with girls completing the program one year earlier. Results suggest that the SNM may impact…

  16. Solar Sail Attitude Control System for the NASA Near Earth Asteroid Scout Mission

    Science.gov (United States)

    Orphee, Juan; Diedrich, Ben; Stiltner, Brandon; Becker, Chris; Heaton, Andrew

    2017-01-01

    An Attitude Control System (ACS) has been developed for the NASA Near Earth Asteroid (NEA) Scout mission. The NEA Scout spacecraft is a 6U cubesat with an eighty-six square meter solar sail for primary propulsion that will launch as a secondary payload on the Space Launch System (SLS) Exploration Mission 1 (EM-1) and rendezvous with a target asteroid after a two year journey, and will conduct science imagery. The spacecraft ACS consists of three major actuating subsystems: a Reaction Wheel (RW) control system, a Reaction Control System (RCS), and an Active Mass Translator (AMT) system. The reaction wheels allow fine pointing and higher rates with low mass actuators to meet the science, communication, and trajectory guidance requirements. The Momentum Management System (MMS) keeps the speed of the wheels within their operating margins using a combination of solar torque and the RCS. The AMT is used to adjust the sign and magnitude of the solar torque to manage pitch and yaw momentum. The RCS is used for initial de-tumble, performing a Trajectory Correction Maneuver (TCM), and performing momentum management about the roll axis. The NEA Scout ACS is able to meet all mission requirements including attitude hold, slews, pointing for optical navigation and pointing for science with margin and including flexible body effects. Here we discuss the challenges and solutions of meeting NEA Scout mission requirements for the ACS design, and present a novel implementation of managing the spacecraft Center of Mass (CM) to trim the solar sail disturbance torque. The ACS we have developed has an applicability to a range of potential missions and does so in a much smaller volume than is traditional for deep space missions beyond Earth.

  17. Use of computed tomography scout film and Hounsfield unit of computed tomography scan in predicting the radio-opacity of urinary calculi in plain kidney, ureter and bladder radiographs.

    Science.gov (United States)

    Chua, Michael E; Gomez, Odina R; Sapno, Lorelei D; Lim, Steve L; Morales, Marcelino L

    2014-07-01

    The objective of this study is to determine the diagnostic utility of computed tomography (CT)- scout film with an optimal non-contrast helical CT scan Hounsfield unit (HU) in predicting the appearance of urinary calculus in the plain kidneys, ureter, urinary bladder (KUB)-radiograph. A prospective cross-sectional study was executed and data were collected from June 2007 to June 2012 at a tertiary hospital. The included subjects were diagnosed to have value, CT-scout film and KUB radiograph appearance were recorded independently by two observers. Univariate logistic analysis with receiver operating characteristic curve was generated to determine the best cut-off HU value of urolithiases not identified in CT-scout film, but determined radio-opaque in KUB X-ray. Subsequently, its sensitivity, specificity, predictive values and likelihood ratios were calculated. Statistical significance was set at P value of 0.05 or less. Two hundred and three valid cases were included. 73 out of 75 CT-scout film detected urolithiasis were identified on plain radiograph and determined as radio-opaque. The determined best cut off value of HU utilized for prediction of radiographic characteristics was 630HU at which urinary calculi were not seen at CT-scout film and were KUB X-ray radio-opaque. The set HU cut-off was established of ideal accuracy with an overall sensitivity of 82.2%, specificity of 96.9% and a positive predictive value of 96.5% and negative predictive value of 83.5%. Urolithiases identified on the CT-scout film were also seen as radiopaque on the KUB radiograph while those stones not visible on the CT-scout film, but above the optimal HU cut-off value of 630 are also likely to be radiopaque.

  18. Design and Development of NEA Scout Solar Sail Deployer Mechanism

    Science.gov (United States)

    Sobey, Alexander R.; Lockett, Tiffany Russell

    2016-01-01

    The 6U (approx.10 cm x 20 cm x 30 cm) cubesat Near Earth Asteroid (NEA) Scout1, projected for launch in September 2018 aboard the maiden voyage of the Space Launch System, will utilize a solar sail as its main method of propulsion throughout its approx.3-year mission to a Near Earth Asteroid. Due to the extreme volume constraints levied onto the mission, an acutely compact solar sail deployment mechanism has been designed to meet the volume and mass constraints, as well as provide enough propulsive solar sail area and quality in order to achieve mission success. The design of such a compact system required the development of approximately half a dozen prototypes in order to identify unforeseen problems, advance solutions, and build confidence in the final design product. This paper focuses on the obstacles of developing a solar sail deployment mechanism for such an application and the lessons learned from a thorough development process. The lessons presented will have significant applications beyond the NEA Scout mission, such as the development of other deployable boom mechanisms and uses for gossamer-thin films in space.

  19. Determination of the permeability of α-, β- and γ-radiation in textile fabrics by Gamma-Scout device

    International Nuclear Information System (INIS)

    Gintibidze, N.; Mardaleishvili, Z.

    2009-01-01

    The goal of the present was the measurement of radiation permeability in textile fabrics by Gamma-Scout device and the comparison of the obtained results with the radiation background of the ambient air. The authors of this article have produced new fiber Fibron-3, which, according to theoretical calculations, reduces permeability of solar radiation. With this in mind, an experiment was performed. Three samples of the knitted cloth from Fibron-3 were taken, and the permeability of solar radiation in them was determined. The measurements were performed on Gamma-Scout device. The comparative analysis of the permeability of solar radiation in fabrics of different fibrous structure was performed. It was inferred that the degree of radiation permeability in fabrics depended on the thread thickness and the fiber structure. (author)

  20. CT guided stereotaxy based on scout view imaging

    Energy Technology Data Exchange (ETDEWEB)

    Wester, K; Kjartansson, O; Bakke, S J

    1987-05-01

    A simple and inexpensive method for CT guided sterotaxy is described. The method requires no extra equipment in the interface between the computer tomograph and the stereotaxic frame, and could therefore easily be adopted in most neurosurgical units. With this method, information from the transaxial CT sections is transferred manually via the scout view image to the operation theater skull X-rays, and thereby to the stereotaxic frame. The method has proved to be sufficiently accurate for all current non-functional stereotaxic procedures in our department during 30 months of testing.

  1. CT guided stereotaxy based on scout view imaging

    International Nuclear Information System (INIS)

    Wester, K.; Kjartansson, O.; Bakke, S.J.; Rikshospitalet, Oslo

    1987-01-01

    A simple and inexpensive method for CT guided sterotaxy is described. The method requires no extra equipment in the interface between the computer tomograph and the stereotaxic frame, and could therefore easily be adopted in most neurosurgical units. With this method, information from the transaxial CT sections is transferred manually via the scout view image to the operation theater skull X-rays, and thereby to the stereotaxic frame. The method has proved to be sufficiently accurate for all current non-functional stereotaxic procedures in our department during 30 months of testing. (orig.)

  2. Near Earth Asteroid Scout Solar Sail Engineering Development Unit Test Suite

    Science.gov (United States)

    Lockett, Tiffany Russell; Few, Alexander; Wilson, Richard

    2017-01-01

    The Near Earth Asteroid (NEA) Scout project is a 6U reconnaissance mission to investigate a near Earth asteroid utilizing an 86m(sub 2) solar sail as the primary propulsion system. This will be the largest solar sail NASA has launched to date. NEA Scout is currently manifested on the maiden voyage of the Space Launch System in 2018. In development of the solar sail subsystem, design challenges were identified and investigated for packaging within a 6U form factor and deployment in cis-lunar space. Analysis was able to capture understanding of thermal, stress, and dynamics of the stowed system as well as mature an integrated sail membrane model for deployed flight dynamics. Full scale system testing on the ground is the optimal way to demonstrate system robustness, repeatability, and overall performance on a compressed flight schedule. To physically test the system, the team developed a flight sized engineering development unit with design features as close to flight as possible. The test suite included ascent vent, random vibration, functional deployments, thermal vacuum, and full sail deployments. All of these tests contributed towards development of the final flight unit. This paper will address several of the design challenges and lessons learned from the NEA Scout solar sail subsystem engineering development unit. Testing on the component level all the way to the integrated subsystem level. From optical properties of the sail material to fold and spooling the single sail, the team has developed a robust deployment system for the solar sail. The team completed several deployments of the sail system in preparation for flight at half scale (4m) and full scale (6.8m): boom only, half scale sail deployment, and full scale sail deployment. This paper will also address expected and received test results from ascent vent, random vibration, and deployment tests.

  3. A Cost Benefit Analysis of Fire Scout Vertical Takeoff and Landing Tactical Unmanned Aerial Vehicle (VTUAV) Operator Alternatives

    Science.gov (United States)

    2012-03-01

    mile mission radius.24 Like the MH-60R manned helicopter, the Fire Scout mission systems suite includes Infrared Imaging, Electro Optical Imaging...homecoming just as sweet." dcmilitary.com. February 21, 2008. http:// ww2 .dcmilitary.com/stories/022108/southpotomac_28121.shtml (accessed February 29... ww2 .dcmilitary.com/stories/022108/southpotomac_28121.shtml (accessed February 29, 2012). Tilghman, Andrew. "Fire Scout Program could open door for

  4. Citizenship and Children's Identity in "The Wonderful Adventures of Nils" and "Scouting for Boys"

    Science.gov (United States)

    Sundmark, Bjorn

    2009-01-01

    "The Wonderful Adventures of Nils" (1906-1907) by Selma Lagerlof and "Scouting for Boys" (1908) by Robert Baden-Powell are characteristic of their time and their respective national and cultural contexts--the Swedish nation state of the early twentieth century and the British Empire. Taking its cue from recent theories on…

  5. The Lunar Scout Program: An international program to survey the Moon from orbit for geochemistry, mineralogy, imagery, geodesy, and gravity

    Science.gov (United States)

    Morrison, Donald A. (Editor)

    1994-01-01

    The Lunar Scout Program was one of a series of attempts by NASA to develop and fly an orbiting mission to the moon to collect geochemical, geological, and gravity data. Predecessors included the Lunar Observer, the Lunar Geochemical Orbiter, and the Lunar Polar Orbiter - missions studied under the auspices of the Office of Space Science. The Lunar Scout Program, however, was an initiative of the Office of Exploration. It was begun in late 1991 and was transferred to the Office of Space Science after the Office of Exploration was disbanded in 1993. Most of the work was done by a small group of civil servants at the Johnson Space Center; other groups also responsible for mission planning included personnel from the Charles Stark Draper Laboratories, the Lawrence Livermore National Laboratory, Boeing, and Martin Marietta. The Lunar Scout Program failed to achieve new start funding in FY 93 and FY 94 as a result of budget downturns, the de-emphasis of the Space Exploration Initiative, and the fact that lunar science did not rate as high a priority as other planned planetary missions, and was cancelled. The work done on the Lunar Scout Program and other lunar orbiter studies, however, represents assets that will be useful in developing new approaches to lunar orbit science.

  6. Waterborne gastroenteritis outbreak at a scouting camp caused by two norovirus genogroups: GI and GII.

    Science.gov (United States)

    ter Waarbeek, Henriëtte L G; Dukers-Muijrers, Nicole H T M; Vennema, Harry; Hoebe, Christian J P A

    2010-03-01

    A cross-border gastroenteritis outbreak at a scouting camp was associated with drinking water from a farmer's well. A retrospective cohort study was performed to identify size and source of the outbreak, as well as other characteristics. Epidemiological investigation included standardized questionnaires about sex, age, risk exposures, illness and family members. Stool and water (100mL) samples were analyzed for bacteria, viruses and parasites. Questionnaires were returned by 84 scouts (response rate 82%), mean age of 13 years. The primary attack rate was 85% (diarrhoea and/or vomiting). Drinking water was the strongest independent risk factor showing a dose-response effect with 50%, 75%, 75%, 93% and 96% case prevalence for 0, 1, 2-3, 4-5 and >5 glasses consumed, respectively. Norovirus (GI.2 Southampton and GII.7 Leeds) was detected in 51 stool specimens (75%) from ill scouts. Water analysis showed fecal contamination, but no norovirus. The secondary attack rate was 20%. This remarkable outbreak was caused by a point-source infection with two genogroups of noroviruses most likely transmitted by drinking water from a well. Finding a dose-response relationship was striking. Specific measures to reduce the risk of waterborne diseases, outbreak investigation and a good international public health network are important.

  7. Circumferential scouting punch biopsies to delineate surgical margin for dermatofibrosarcoma protuberans

    Directory of Open Access Journals (Sweden)

    Tsung-Mao Huang

    2012-03-01

    Full Text Available Dermatofibrosarcoma protuberans (DFSP is an uncommon soft-tissue tumor involving the dermis and subcutaneous tissue with a high local recurrence rate after standard excision. Mohs micrographic surgery offers a lower recurrence rate. However, the procedure requires multiple stages of excision with intraoperative histopathological mapping, which is time consuming and expensive. We report our experience of using circumferential scouting punch biopsy technique in five patients to determine in advance the resection margins for DFSP prior to wide excision. Multiple 4 mm punches, usually eight in number, were performed 1–2.5 cm around the palpable borders of DFSP to delineate the resection margins in five consecutive patients. Tumors were excised at a later date along the margin defined by these biopsies and the wounds were repaired with skin graft. The operation was completed in 2 hours in all cases excluding one that required frozen sections for deep margin. No recurrence was noted 2–10 years after the operations. The results suggest that circumferential scouting punch biopsies before wide excision may be an alternative method to define the resection margins for DFSP when Mohs surgery is not available.

  8. Bringing Astronomy Activities and Science Content to Girls Locally and Nationally: A Girl Scout and NIRCam Collaboration

    Science.gov (United States)

    Higgins, M. L.; Lebofsky, L. A.; McCarthy, D. W.; Lebofsky, N.

    2013-04-01

    In 2003, the University of Arizona's (UA) NIRCam EPO team (NASA James Webb Space Telescope's Near-Infrared Camera) and the Girl Scouts of Southern Arizona began a long-term collaboration to bring STEM and astronomy activities and concepts to adult Girl Scout volunteers and staff and, in turn, their councils and girls, i.e., to train the trainers. Nationally, our goal is to reach adult volunteers and staff in all 112 councils. To date, this program has reached nearly 240 adults from 78 councils in 41 states, DC, Guam, and Japan, bringing together adult volunteers and staff, UA graduate students, and NIRCam scientists and educators to experience Arizona's dark skies.

  9. The Near Earth Object Scout Spacecraft: A Low Cost Approach to in-situ Characterization of the NEO Population

    Science.gov (United States)

    Koontz, Steven L.; Condon, Gerald; Graham, Lee; Bevilacqua, Ricardo

    2014-01-01

    In this paper we describe a micro/nano satellite spacecraft and a supporting mission profile and architecture designed to enable preliminary in-situ characterization of a significant number of Near Earth Objects (NEOs) at reasonable cost. The spacecraft will be referred to as the NEO Scout. NEO Scout spacecraft are to be placed in GTO, GEO, or cis-lunar space as secondary payloads on launch vehicles headed for GTO or beyond and will begin their mission after deployment from the launcher. A distinguishing key feature of the NEO scout system is to design the mission timeline and spacecraft to rendezvous with and land on the target NEOs during close approach to the Earth-Moon system using low-thrust/high- impulse propulsion systems. Mission feasibility and preliminary design analysis are presented along with detailed trajectory calculations. The use of micro/nano satellites in low-cost interplanetary exploration is attracting increasing attention and is the subject of several annual workshops and published design studies (1-4). The NEO population consists of those asteroids and short period comets orbiting the Sun with a perihelion of 1.3 astronomical units or less (5-8). As of July 30, 2013 10065 Near-Earth objects have been discovered. The spin rate, mass, density, surface physical (especially mechanical) properties, composition, and mineralogy of the vast majority of these objects are highly uncertain and the limited available telescopic remote sensing data imply a very diverse population (5-8). In-situ measurements by robotic spacecraft are urgently needed to provide the characterization data needed to support hardware and mission design for more ambitious human and robotic NEO operations. Large numbers of NEOs move into close proximity with the Earth-Moon system every year (9). The JPL Near-Earth Object Human Space Flight Accessible Targets Study (NHATS) (10) has produced detailed mission profile and delta V requirements for various NEO missions ranging from 30

  10. A modified scout bee for artificial bee colony algorithm and its performance on optimization problems

    Directory of Open Access Journals (Sweden)

    Syahid Anuar

    2016-10-01

    Full Text Available The artificial bee colony (ABC is one of the swarm intelligence algorithms used to solve optimization problems which is inspired by the foraging behaviour of the honey bees. In this paper, artificial bee colony with the rate of change technique which models the behaviour of scout bee to improve the performance of the standard ABC in terms of exploration is introduced. The technique is called artificial bee colony rate of change (ABC-ROC because the scout bee process depends on the rate of change on the performance graph, replace the parameter limit. The performance of ABC-ROC is analysed on a set of benchmark problems and also on the effect of the parameter colony size. Furthermore, the performance of ABC-ROC is compared with the state of the art algorithms.

  11. Lead sheathing of ship hulls in the Roman period: Archaeometallurgical characterisation

    Energy Technology Data Exchange (ETDEWEB)

    Kahanov, Yaacov, E-mail: yak@research.haifa.ac.il [Leon Recanati Institute for Maritime Studies, University of Haifa, Haifa 31905 (Israel); Ashkenazi, Dana [Faculty of Engineering, Tel Aviv University, Ramat Aviv 69978 (Israel)

    2011-08-15

    An archaeometallurgical analysis of samples of lead sheathing from five ships of the Roman period was carried out in order to determine their composition and microstructure, and to obtain a better understanding of their manufacturing processes. The examinations included optical microscopy of metallographic cross-sections, microhardness tests, scanning electron microscopy, including energy dispersive spectroscopy, and X-ray photoelectron spectroscopy. The results show that the samples were all composed of lead covered with an oxide layer. The sheet thicknesses, microhardness values and microhardness distribution, as well as the grain size distribution, led to the conclusion that all of the sheets were produced by the same technology, using hammering, and were probably used for the same purpose. The presence of antimony was observed in the sample from the Roman ship from Caesarea, which may hint at an Italian (Sardinian) origin of the material, and perhaps of the ship. - Research Highlights: {yields} During the Roman period ship hulls were sheathed with lead. {yields} Five samples have been analysed for their characteristics and manufacturing process. {yields} The process was cold-working (strain-hardening) using hammering. {yields} The lead was open-casted on a flat stone, and later hammered at room temperature. {yields} Antimony in the Caesarea shipwreck may indicate an Italian origin of construction.

  12. Solar Torque Management for the Near Earth Asteroid Scout CubeSat Using Center of Mass Position Control

    Science.gov (United States)

    Orphee, Juan; Heaton, Andrew; Diedrich, Ben; Stiltner, Brandon C.

    2018-01-01

    A novel mechanism, the Active Mass Translator (AMT), has been developed for the NASA Near Earth Asteroid (NEA) Scout mission to autonomously manage the spacecraft momentum. The NEA Scout CubeSat will launch as a secondary payload onboard Exploration Mission 1 of the Space Launch System. To accomplish its mission, the CubeSat will be propelled by an 86 square-meter solar sail during its two-year journey to reach asteroid 1991VG. NEA Scout's primary attitude control system uses reaction wheels for holding attitude and performing slew maneuvers, while a cold gas reaction control system performs the initial detumble and early trajectory correction maneuvers. The AMT control system requirements, feedback architecture, and control performance will be presented. The AMT reduces the amount of reaction control propellant needed for momentum management and allows for smaller capacity reaction wheels suitable for the limited 6U spacecraft volume. The reduced spacecraft mass allows higher in-space solar sail acceleration, thus reducing time-of-flight. The reduced time-of-flight opens the range of possible missions, which is limited by the lifetime of typical non-radiation tolerant CubeSat avionics exposed to the deep-space environment.

  13. Safety analysis of holmium-166 microsphere scout dose imaging during radioembolisation work-up. A cohort study

    Energy Technology Data Exchange (ETDEWEB)

    Braat, Arthur J.A.T.; Prince, Jip F.; Rooij, Rob van; Bruijnen, Rutger C.G.; Bosch, Maurice A.A.J. van den; Lam, Marnix G.E.H. [University Medical Center Utrecht, Department of Radiology and Nuclear Medicine, Utrecht (Netherlands)

    2018-03-15

    Radioembolisation is generally preceded by a scout dose of technetium-99m-macroaggregated albumin to estimate extrahepatic shunting of activity. Holmium-166 microspheres can be used as a scout dose (±250 MBq) and as a therapeutic dose. The general toxicity of a holmium-166 scout dose ({sup 166}Ho-SD) and safety concerns of an accidental extrahepatic deposition of {sup 166}Ho-SD were investigated. All patients who received a {sup 166}Ho-SD in our institute were reviewed for general toxicity and extrahepatic depositions. The absorbed dose in extrahepatic tissue was calculated on SPECT/CT and correlated to clinical toxicities. In total, 82 patients were included. No relevant clinical toxicity occurred. Six patients had an extrahepatic deposition of {sup 166}Ho-SD (median administered activity 270 MBq). The extrahepatic depositions (median activity 3.7 MBq) were located in the duodenum (3x), gastric fundus, falciform ligament and the lesser curvature of the stomach, and were deposited in a median volume of 15.3 ml, which resulted in an estimated median absorbed dose of 3.6 Gy (range 0.3-13.8 Gy). No adverse events related to the extrahepatic deposition of the {sup 166}Ho-SD occurred after a median follow-up of 4 months (range 1-12 months). These results support the safety of 250 MBq {sup 166}Ho-SD in a clinical setting. (orig.)

  14. Comparison of computed tomography scout based reference point localization to conventional film and axial computed tomography.

    Science.gov (United States)

    Jiang, Lan; Templeton, Alistair; Turian, Julius; Kirk, Michael; Zusag, Thomas; Chu, James C H

    2011-01-01

    Identification of source positions after implantation is an important step in brachytherapy planning. Reconstruction is traditionally performed from films taken by conventional simulators, but these are gradually being replaced in the clinic by computed tomography (CT) simulators. The present study explored the use of a scout image-based reconstruction algorithm that replaces the use of traditional film, while exhibiting low sensitivity to metal-induced artifacts that can appear in 3D CT methods. In addition, the accuracy of an in-house graphical software implementation of scout-based reconstruction was compared with seed location reconstructions for 2 phantoms by conventional simulator and CT measurements. One phantom was constructed using a planar fixed grid of 1.5-mm diameter ball bearings (BBs) with 40-mm spacing. The second was a Fletcher-Suit applicator embedded in Styrofoam (Dow Chemical Co., Midland, MI) with one 3.2-mm-diameter BB inserted into each of 6 surrounding holes. Conventional simulator, kilovoltage CT (kVCT), megavoltage CT, and scout-based methods were evaluated by their ability to calculate the distance between seeds (40 mm for the fixed grid, 30-120 mm in Fletcher-Suit). All methods were able to reconstruct the fixed grid distances with an average deviation of <1%. The worst single deviations (approximately 6%) were exhibited in the 2 volumetric CT methods. In the Fletcher-Suit phantom, the intermodality agreement was within approximately 3%, with the conventional sim measuring marginally larger distances, with kVCT the smallest. All of the established reconstruction methods exhibited similar abilities to detect the distances between BBs. The 3D CT-based methods, with lower axial resolution, showed more variation, particularly with the smaller BBs. With a software implementation, scout-based reconstruction is an appealing approach because it simplifies data acquisition over film-based reconstruction without requiring any specialized equipment

  15. Scout-view assisted interior digital tomosynthesis (iDTS) based on compressed-sensing theory

    Science.gov (United States)

    Park, S. Y.; Kim, G. A.; Cho, H. S.; Seo, C. W.; Je, U. K.; Park, C. K.; Lim, H. W.; Kim, K. S.; Lee, D. Y.; Lee, H. W.; Kang, S. Y.; Park, J. E.; Woo, T. H.; Lee, M. S.

    2017-12-01

    Conventional digital tomosynthesis (DTS) based on the filtered-backprojection (FBP) reconstruction requires full field-of-view scan and also relatively dense projections, which results in still high dose for medical imaging purposes. In this work, to overcome these difficulties, we propose a new type of DTS examinations, the so-called scout-view assisted interior DTS (iDTS), in which the x-ray beam span covers only a small region-of-interest (ROI) containing target diagnosis with the help of some scout views and they are used in the reconstruction to add additional information to interior ROI otherwise absent with conventional iDTS reconstruction methods. We considered an effective iterative algorithm based on compressed-sensing theory, rather than the FBP-based algorithm, for more accurate iDTS reconstruction. We implemented the proposed algorithm, performed a systematic simulation and experiment, and investigated the image characteristics. We successfully reconstructed iDTS images of substantially high accuracy and no truncation artifacts by using the proposed method, preserving superior image homogeneity, edge sharpening, and in-plane spatial resolution.

  16. The Integration of the Fire Scout Tactical Unmanned Aerial System into Littoral Combat Ship Missions

    National Research Council Canada - National Science Library

    Marsh, James J

    2007-01-01

    ...) is an effective mission multiplier for the Littoral Combat Ship (LCS). The U.S. Navy relies heavily on unmanned systems, such as the Fire Scout UAS, to enable LCS to conduct several complex littoral missions...

  17. STICS, SCOUTs and p53 signatures; a new language for pelvic serous carcinogenesis.

    Science.gov (United States)

    Mehra, Karishma; Mehrad, Mitra; Ning, Geng; Drapkin, Ronny; McKeon, Frank D; Xian, Wa; Crum, Christopher P

    2011-01-01

    The events leading to the most common and most lethal ovarian carcinoma - high grade serous carcinoma - have been poorly understood. However, the detailed pathologic study of asymptomatic women with germ-line BRCA 1 or BRCA2 (BCRA+) mutations has unearthed an early malignancy, serous tubal intraepithelial carcinomas (STIC), which has linked many peritoneal and ovarian serous carcinomas to the fimbria. The distinction between high-grade serous and endometrioid carcinomas continues to narrow, with shared alterations in expression of pTEN, PAX2 and p53. Moreover, the discovery of clonal alterations in p53 in benign tubal epithelium, - p53 signatures - has established a foundation for a serous cancer precursor in the fimbria. We have expanded this concept to include a generic secretory cell outgrowth (SCOUT) in the fallopian tube that is associated with altered PAX2 expression. As the repertoire of gene alterations is expanded and its link to serous carcinogenesis clarified, a cogent pathway to high-grade Mullerian carcinomas will emerge. This will challenge conventional thinking about ovarian carcinogenesis but will provide a new template for studies of ovarian cancer prevention.

  18. Leveraging Non-Cognitive Testing to Predict Success at USMC Scout Sniper Course

    Science.gov (United States)

    2017-03-01

    whether aptitude requirements translate to job performance. Mayberry (1990) determines the ASVAB a valid predictor of success for infantrymen...Reduction Project (0704-0188) Washington, DC 20503. 1. AGENCY USE ONLY (Leave blank) 2. REPORT DATE March 2017 3. REPORT TYPE AND DATES COVERED...success at scout sniper school. We use data from 2012 through 2016 containing more than 700 Marines from every infantry military occupational specialty

  19. Semi-Automated Hydrophobic Interaction Chromatography Column Scouting Used in the Two-Step Purification of Recombinant Green Fluorescent Protein

    Science.gov (United States)

    Murphy, Patrick J. M.

    2014-01-01

    Background Hydrophobic interaction chromatography (HIC) most commonly requires experimental determination (i.e., scouting) in order to select an optimal chromatographic medium for purifying a given target protein. Neither a two-step purification of untagged green fluorescent protein (GFP) from crude bacterial lysate using sequential HIC and size exclusion chromatography (SEC), nor HIC column scouting elution profiles of GFP, have been previously reported. Methods and Results Bacterial lysate expressing recombinant GFP was sequentially adsorbed to commercially available HIC columns containing butyl, octyl, and phenyl-based HIC ligands coupled to matrices of varying bead size. The lysate was fractionated using a linear ammonium phosphate salt gradient at constant pH. Collected HIC eluate fractions containing retained GFP were then pooled and further purified using high-resolution preparative SEC. Significant differences in presumptive GFP elution profiles were observed using in-line absorption spectrophotometry (A395) and post-run fluorimetry. SDS-PAGE and western blot demonstrated that fluorometric detection was the more accurate indicator of GFP elution in both HIC and SEC purification steps. Comparison of composite HIC column scouting data indicated that a phenyl ligand coupled to a 34 µm matrix produced the highest degree of target protein capture and separation. Conclusions Conducting two-step protein purification using the preferred HIC medium followed by SEC resulted in a final, concentrated product with >98% protein purity. In-line absorbance spectrophotometry was not as precise of an indicator of GFP elution as post-run fluorimetry. These findings demonstrate the importance of utilizing a combination of detection methods when evaluating purification strategies. GFP is a well-characterized model protein, used heavily in educational settings and by researchers with limited protein purification experience, and the data and strategies presented here may aid in

  20. 76 FR 71564 - ScanScout, Inc.; Analysis of Proposed Consent Order To Aid Public Comment

    Science.gov (United States)

    2011-11-18

    ... behavioral advertising, the practice of collecting and storing information about consumers' online activities... behavioral advertising. ScanScout's privacy policy stated that by changing their browser settings, consumers... data for online behavioral advertising. First, within thirty (30) days after service of the proposed...

  1. Scouting For Approval: Lessons on Medical Device Regulation in an Era of Crowdfunding from Scanadu's "Scout".

    Science.gov (United States)

    Smith, Colleen

    2015-01-01

    Internet crowdfunding, a new and increasingly popular method of raising capital to develop products and businesses, has recently come into conflict with the Food and Drug Administration's (FDA's) regulation of medical devices. This Article examines the issues that arise when companies pre-sell medical devices via crowdfunding campaigns before gaining FDA approval of the devices. Because Internet crowdfunding has only been in use for a few years, little has been written about it academically, particularly about its interaction with FDA regulations. The rising interest in crowdfunding, coupled with the downturn in investment in the American medical device industry, make this a salient issue that is ripe for FDA review. This Article uses the crowdfunding campaign Scanadu, a medical device company, conducted in 2013 to raise money to develop its in-home diagnostic device, the "Scout," as a starting point for this analysis. Because it is extremely costly to develop a device and obtain FDA approval, medical device companies should be able to utilize crowdfunding to raise the necessary capital. However, because of the possible dangers medical devices pose, FDA needs to review the risks created by allowing companies to crowdfund medical devices and should issue guidance to help companies comply with FDA regulations while still allowing them to take advantage of the benefits of crowdfunding. This guidance should ensure the continued commitment to consumer safety that is at the core of FDA regulation.

  2. Energy behaviours of northern California Girl Scouts and their families

    International Nuclear Information System (INIS)

    Boudet, Hilary; Ardoin, Nicole M.; Flora, June; Armel, K. Carrie; Desai, Manisha; Robinson, Thomas N.

    2014-01-01

    Climate change is likely the most critical societal challenge to the futures of today's children. Mitigation will require a concerted effort to change household energy behaviour—electricity use, transportation and food consumption patterns. A first step to changing behaviour is to better understand current behaviour and its intrapersonal (knowledge and attitudes), interpersonal (norms, communication and behaviour) and contextual (demographics and geography) correlates. To date, our understanding of the energy behaviours of children is limited. To begin to fill this gap, we report the results of a survey on the electricity, transportation and food-related energy behaviours of 323 fourth- and fifth-grade girls and their parents in 31 Girl Scout troops in Northern California. Our findings show positive attitudes and perceived norms toward energy-saving behaviours among child and adult respondents, but low or moderate levels of knowledge, communication, and behaviour, particularly for behaviours that require adult assistance. Girls’ choices about electricity behaviours appear to be governed by intrapersonal and interpersonal influences, while transportation behaviour is constrained by geographic context. Food-related behaviour, particularly meat consumption, was not readily modelled. Policy and education-related implications for future interventions aimed at enhancing children's energy-saving behaviours are discussed. - Highlights: • We surveyed 323 fourth and fifth grade Girl Scouts and parents about energy behaviours. • We asked about electricity, transportation and food behaviour and its correlates. • Girls’ electricity behaviours are linked to intrapersonal and interpersonal influences. • Girls’ transportation behaviour is constrained by geographic context. • Girls’ food behaviour, particularly meat consumption, was not readily modelled

  3. Quantitative 89Zr immuno-PET for in vivo scouting of 90Y-labeled monoclonal antibodies in xenograft-bearing nude mice.

    NARCIS (Netherlands)

    Verel, I.; Visser, G.W.; Boellaard, R.; Boerman, O.C.; Eerd-Vismale, J.E.M. van; Snow, G.B.; Lammertsma, A.A.; Dongen, G.A.M.S. van

    2003-01-01

    Immuno-PET as a scouting procedure before radioimmunotherapy (RIT) aims at the confirmation of tumor targeting and the accurate estimation of radiation dose delivery to both tumor and normal tissues. Immuno-PET with (89)Zr-labeled monoclonal antibodies (mAbs) and (90)Y-mAb RIT might form such a

  4. The Philippine Scouts: A Case Study in the Use of Indigenous Soldiers, Northern Luzon, the Philippine Islands, 1899

    Science.gov (United States)

    1983-05-31

    26 Robert Baden-Powell..o.. ...... .... ................... 26 Zulu Scoutso .... 0......0...................... 27 Elminas and Adansi Scouts...return, and braggadocio-like, swear vengeance, threatening to exterminate the tribe ; and mounting their caballos, pretend to give chase, buf taking good...outside of Columbus on the Platte River in Nebraska, had come to know the Pawnee tribe and speak the Pawnee language. During the fall of 1860, both Frank

  5. Evaluation models of some morphological characteristics for talent scouting in sport.

    Science.gov (United States)

    Rogulj, Nenad; Papić, Vladan; Cavala, Marijana

    2009-03-01

    In this paper, for the purpose of expert system evaluation within the scientific project "Talent scouting in sport", two methodological approaches for recognizing an athlete's morphological compatibility for various sports has been presented, evaluated and compared. First approach is based on the fuzzy logic and expert opinion about compatibility of proposed hypothetical morphological models for 14 different sports which are part of the expert system. Second approach is based on determining the differences between morphological characteristics of a tested individual and top athlete's morphological characteristics for particular sport. Logical and mathematical bases of both methodological approaches have been explained in detail. High prognostic efficiency in recognition of individual's sport has been determined. Some improvements in further development of both methods have been proposed. Results of the research so far suggest that this or similar approaches can be successfully used for detection of individual's morphological compatibility for different sports. Also, it is expected to be useful in the selection of young talents for particular sport.

  6. Exploration and exploitation of food sources by social insect colonies: a revision of the scout-recruit concept

    NARCIS (Netherlands)

    Biesmeijer, J.C.; Vries, Han de

    2000-01-01

    Social insect colonies need to explore and exploit multiple food sources simultaneously and efficiently. At the individual level, this colony-level behaviour has been thought to be taken care of by two types of individual: scouts that independently search for food, and recruits that are

  7. MASCOT—The Mobile Asteroid Surface Scout Onboard the Hayabusa2 Mission

    Science.gov (United States)

    Ho, Tra-Mi; Baturkin, Volodymyr; Grimm, Christian; Grundmann, Jan Thimo; Hobbie, Catherin; Ksenik, Eugen; Lange, Caroline; Sasaki, Kaname; Schlotterer, Markus; Talapina, Maria; Termtanasombat, Nawarat; Wejmo, Elisabet; Witte, Lars; Wrasmann, Michael; Wübbels, Guido; Rößler, Johannes; Ziach, Christian; Findlay, Ross; Biele, Jens; Krause, Christian; Ulamec, Stephan; Lange, Michael; Mierheim, Olaf; Lichtenheldt, Roy; Maier, Maximilian; Reill, Josef; Sedlmayr, Hans-Jürgen; Bousquet, Pierre; Bellion, Anthony; Bompis, Olivier; Cenac-Morthe, Celine; Deleuze, Muriel; Fredon, Stephane; Jurado, Eric; Canalias, Elisabet; Jaumann, Ralf; Bibring, Jean-Pierre; Glassmeier, Karl Heinz; Hercik, David; Grott, Matthias; Celotti, Luca; Cordero, Federico; Hendrikse, Jeffrey; Okada, Tatsuaki

    2017-07-01

    On December 3rd, 2014, the Japanese Space Agency (JAXA) launched successfully the Hayabusa2 (HY2) spacecraft to its journey to Near Earth asteroid (162173) Ryugu. Aboard this spacecraft is a compact landing package, MASCOT (Mobile Asteroid surface SCOuT), which was developed by the German Aerospace Centre (DLR) in collaboration with the Centre National d'Etudes Spatiales (CNES). Similar to the famous predecessor mission Hayabusa, Hayabusa2, will also study an asteroid and return samples to Earth. This time, however, the target is a C-type asteroid which is considered to be more primitive than (25143) Itokawa and provide insight into an even earlier stage of our Solar System.

  8. Implications of Boy Scout group use of public lands for natural resource managers: a regional comparison

    Science.gov (United States)

    Gail A. Vander Stoep

    1992-01-01

    Resource managers can apply group-specific rather than generic communications and management strategies to different public land user groups. This study compares use patterns of one user group, Boy Scout troops, from two regions of the United States. It identifies their public land use patterns, activities, needs, and motivations. Results can be used by resource...

  9. Redskins in Bluecoats: A Strategic and Cultural Analysis of General George Crooks Use of Apache Scouts in the Second Apache Campaign, 1882-1886

    Science.gov (United States)

    2010-03-31

    Scouts ...................................................................... .44 Figure 7. Captain John Gregory Bourke ...John Gregory Bourke (see Figure 7), served with him "for more than 15 years ... as a member of his military staff.,,3o Following his retirement, Bourke ...Bureau of Indian affairs. John Bourke said of Crook in an obituary, "The story of his administration of Indian Affairs in that, as in every other

  10. Scout fourth stage attitude and velocity control (AVC) system feasibility study

    Science.gov (United States)

    Byars, L. B.

    1975-01-01

    The feasibility of incorporating a guidance system in the Scout fourth stage to achieve a significant improvement in expected payload delivery accuracy is studied. The technical investigations included the determination of the AVC equipment performance requirements, establishment of qualification and acceptance test levels, generation of layouts illustrating design approaches for the upper D and payload transition sections to incorporate the hardware, and the preparation of a vendor bid package. Correction concepts, utilizing inertial velocity and attitude, were identified and evaluated. Fourth stage attitude adjustments as determined from inertial velocity variation through the first three stages and a final velocity correction based upon the measured in-plane component errors at injection were employed. Results show radical reductions in apogee-perigee deviations.

  11. Wellness-Promoting Practices Through Girl Scouts: A Pragmatic Superiority Randomized Controlled Trial With Additional Dissemination.

    Science.gov (United States)

    Cull, Brooke J; Dzewaltowski, David A; Guagliano, Justin M; Rosenkranz, Sara K; Knutson, Cassandra K; Rosenkranz, Richard R

    2018-01-01

    To evaluate the effectiveness of in-person versus online Girl Scout leader wellness training for implementation of wellness-promoting practices during troop meetings (phase I) and to assess training adoption and current practices across the council (phase II). Pragmatic superiority trial (phase 1) followed by serial cross-sectional study (phase II). Girl Scout troop meetings in Northeast Kansas. Eighteen troop leaders from 3 counties (phase 1); 113 troop leaders from 7 counties (phase II). Phase I: Troop leaders attended 2 wellness training sessions (first in groups, second individually), wherein leaders set wellness-promoting practice implementation goals, self-monitored progress, and received guidance and resources for implementation. Leaders received the intervention in person or online. Phase I: At baseline and postintervention, leaders completed a wellness-promoting practice implementation questionnaire assessing practices during troop meetings (max score = 11). Phase II: Leaders completed a survey about typical troop practices and interest in further training. Phase I: Generalized linear mixed modeling. Phase I: In-person training increased wellness-promoting practice implementation more than online training (in person = 2.1 ± 1.8; online = 0.2 ± 1.2; P = .022). Phase II: Fifty-six percent of leaders adopted the training. For 8 of 11 wellness categories, greater than 50% of leaders employed wellness-promoting practices. In-person training was superior to online training for improvements in wellness-promoting practices. Wellness training was adopted by the majority of leaders across the council.

  12. Evolution of periodicity in periodical cicadas.

    Science.gov (United States)

    Ito, Hiromu; Kakishima, Satoshi; Uehara, Takashi; Morita, Satoru; Koyama, Takuya; Sota, Teiji; Cooley, John R; Yoshimura, Jin

    2015-09-14

    Periodical cicadas (Magicicada spp.) in the USA are famous for their unique prime-numbered life cycles of 13 and 17 years and their nearly perfectly synchronized mass emergences. Because almost all known species of cicada are non-periodical, periodicity is assumed to be a derived state. A leading hypothesis for the evolution of periodicity in Magicicada implicates the decline in average temperature during glacial periods. During the evolution of periodicity, the determinant of maturation in ancestral cicadas is hypothesized to have switched from size dependence to time (period) dependence. The selection for the prime-numbered cycles should have taken place only after the fixation of periodicity. Here, we build an individual-based model of cicadas under conditions of climatic cooling to explore the fixation of periodicity. In our model, under cold environments, extremely long juvenile stages lead to extremely low adult densities, limiting mating opportunities and favouring the evolution of synchronized emergence. Our results indicate that these changes, which were triggered by glacial cooling, could have led to the fixation of periodicity in the non-periodical ancestors.

  13. Monoclonal antibody proteomics: use of antibody mimotope displaying phages and the relevant synthetic peptides for mAb scouting.

    Science.gov (United States)

    Hajdú, István; Flachner, Beáta; Bognár, Melinda; Végh, Barbara M; Dobi, Krisztina; Lőrincz, Zsolt; Lázár, József; Cseh, Sándor; Takács, László; Kurucz, István

    2014-08-01

    Monoclonal antibody proteomics uses nascent libraries or cloned (Plasmascan™, QuantiPlasma™) libraries of mAbs that react with individual epitopes of proteins in the human plasma. At the initial phase of library creation, cognate protein antigen and the epitope interacting with the antibodies are not known. Scouting for monoclonal antibodies (mAbs) with the best binding characteristics is of high importance for mAb based biomarker assay development. However, in the absence of the identity of the cognate antigen the task represents a challenge. We combined phage display, and surface plasmon resonance (Biacore) experiments to test whether specific phages and the respective mimotope peptides obtained from large scale studies are applicable to determine key features of antibodies for scouting. We show here that mAb captured phage-mimotope heterogeneity that is the diversity of the selected peptide sequences, is inversely correlated with an important binding descriptor; the off-rate of the antibodies and that represents clues for driving the selection of useful mAbs for biomarker assay development. Carefully chosen synthetic mimotope peptides are suitable for specificity testing in competitive assays using the target proteome, in our case the human plasma. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. Comparison of nevirapine plasma concentrations between lead-in and steady-state periods in Chinese HIV-infected patients.

    Directory of Open Access Journals (Sweden)

    Huijuan Kou

    Full Text Available To investigate the potential of nevirapine 200 mg once-daily regimen and evaluate the influence of patient characteristics on nevirapine concentrations.This was a prospective, multicentre cohort study with 532 HIV-infected patients receiving nevirapine as a part of their initial antiretroviral therapy. Plasma samples were collected at trough or peak time at the end of week 2 (lead-in period and week 4, 12, 24, 36, and 48 (steady-state period, and nevirapine concentrations were determined using a validated HPLC method. Potential influencing factors associated with nevirapine concentrations were evaluated using univariate and multivariate logistic regression.A total of 2348 nevirapine plasma concentrations were collected, including 1510 trough and 838 peak values. The median nevirapine trough and peak concentration during the lead-in period were 4.26 µg/mL (IQR 3.05-5.61 and 5.07 µg/mL (IQR 3.92-6.44 respectively, which both exceeded the recommended thresholds of nevirapine plasma concentrations. Baseline hepatic function had a moderate effect on median nevirapine trough concentrations at week 2 (4.25 µg/mL v.s. 4.86 µg/mL, for ALT <1.5 × ULN and ≥ 1.5 × ULN, respectively, P = 0.045. No significant difference was observed in median nevirapine trough concentration between lead-in and steady-state periods in patients with baseline ALT and AST level ≥ 1.5 × ULN (P = 0.171, P = 0.769, which was different from the patients with ALT/AST level <1.5ULN. The median trough concentrations were significantly higher in HIV/HCV co-infected patients than those without HCV at week 48 (8.16 µg/mL v.s. 6.15 µg/mL, P = 0.004.The 200 mg once-daily regimen of nevirapine might be comparable to twice-daily in plasma pharmacokinetics in Chinese population. Hepatic function prior to nevirapine treatment and HIV/HCV coinfection were significantly associated with nevirapine concentrations.

  15. Fourier Imaging X-ray Spectrometer (FIXS) for the Argentinian, Scout-launched satelite de Aplicaciones Cienficas-1 (SAC-1)

    International Nuclear Information System (INIS)

    Dennis, B.R.; Crannell, C.J.; Desai, U.D.

    1988-01-01

    The Fourier Imaging X-ray Spectrometer (FIXS) is one of four instruments on SAC-1, the Argentinian satellite being proposed for launch by NASA on a Scout rocket in 1992/3. The FIXS is designed to provide solar flare images at X-ray energies between 5 and 35 keV. Observations will be made on arcsecond size scales and subsecond time scales of the processes that modify the electron spectrum and the thermal distribution in flaring magnetic structures

  16. Optimal base-stock policy for the inventory system with periodic review, backorders and sequential lead times

    DEFF Research Database (Denmark)

    Johansen, Søren Glud; Thorstenson, Anders

    2008-01-01

    We extend well-known formulae for the optimal base stock of the inventory system with continuous review and constant lead time to the case with periodic review and stochastic, sequential lead times. Our extension uses the notion of the 'extended lead time'. The derived performance measures...

  17. Analogue spies in a digital world : changing technology and attitudes on confidentiality make an oilfield scout's job harder than ever

    Energy Technology Data Exchange (ETDEWEB)

    Stastny, P.

    2009-04-15

    Spying amongst oil companies is now declining as a result of cultural shifts in how privacy is viewed as well as by new court decisions on how confidential information is used to gain competitive advantages. In the 1970s, oil company scouts used visual monitoring as a means of gaining information related to oil field technologies. New digital communications processes mean that scouts can no longer eavesdrop on analogue communications equipment using radio equipment. Energy companies are now enjoying an unprecedented level of security. Satellite digital communications minimize the risk of in-field interception by sending signals directly upward from a localized point. Although cellphone scanning equipment is available, it is illegal in Canada. New privacy rules state that listening to a cell phone conversation without the consent of the people talking is now illegal. Devices have also been designed to intercept communications of new digital mobile units. However, the equipment is costly and civilian use of it is illegal. Cellphone technologies are advancing at such a rapid rate that many new spying devices become obsolete very quickly. It was concluded that a recent case in which a small oil and gas operator bid on leases days before a larger company won when the larger company proved that the bid was based on the misuse of confidential data. 3 figs.

  18. Radiation Dose Reduction in CT Fluoroscopy-Guided Cervical Transforaminal Epidural Steroid Injection by Modifying Scout and Planning Steps

    Energy Technology Data Exchange (ETDEWEB)

    Paik, Nam Chull, E-mail: pncspine@gmail.com [Arumdaun Wooldul Spine Hospital, Department of Radiology (Korea, Republic of)

    2016-04-15

    Background and PurposeIn CT fluoroscopy (CTF)-guided cervical transforaminal epidural steroid injection (TFESI), the majority of radiation dose is contributed by the planning CT scan rather than the CTF procedure itself. We replaced the planning helical CT with a spot CTF and accordingly changed the patient posture during scout and planning scans. The aim of this study was to test whether radiation dose reduction would be achieved by this protocol modification while still maintaining technical performance.MethodsOverall, 338 consecutive procedures before (control group: n = 163) and after (study group: n = 175) instituting the above-mentioned protocol modification were analyzed retrospectively, comparing patient characteristics (age, sex, neck diameter, and level injected) and technical performance [technical success rate, dose-length product (DLP), inadvertent contrast flow incidence, number of CTF acquisitions, and procedural time] between the two groups.ResultsAll injections were technically successful at every level from C3–C4 to C7–T1 without serious complications in both groups. The median DLP of the study group (7.92 mGy·cm) was significantly reduced compared to that of the control group (39.05 mGy·cm, P < 0.001). There were no significant differences between the two groups regarding the incidence of inadvertent contrast flow (20.6 vs. 17.2 %, P = 0.426), number of CTF acquisitions (median 5 vs. 4, P = 0.123), and the procedural time (median 6.62 vs. 6.90 min, P = 0.100).ConclusionsWhen conducting CTF-guided cervical TFESIs, a significant radiation dose reduction (median 79.7 % in DLP) can be achieved by modifying scout and planning steps, without compromising the technical performance.

  19. 77 FR 478 - Petition Requesting Exception From the Lead Content Limits; Reopening of the Comment Period

    Science.gov (United States)

    2012-01-05

    ... the Lead Content Limits; Reopening of the Comment Period AGENCY: U.S. Consumer Product Safety... content limit under section 101(b) of the Consumer Product Safety Improvement Act of 2008 (``CPSIA''), as... contain lead content in excess of 100 ppm manufactured after August 12, 2011, are considered to be banned...

  20. The Fourier Imaging X-ray Spectrometer (FIXS) for the Argentinian, Scout-launched satelite de Aplicaciones Cienficas-1 (SAC-1)

    Science.gov (United States)

    Dennis, Brian R.; Crannell, Carol JO; Desai, Upendra D.; Orwig, Larry E.; Kiplinger, Alan L.; Schwartz, Richard A.; Hurford, Gordon J.; Emslie, A. Gordon; Machado, Marcos; Wood, Kent

    1988-01-01

    The Fourier Imaging X-ray Spectrometer (FIXS) is one of four instruments on SAC-1, the Argentinian satellite being proposed for launch by NASA on a Scout rocket in 1992/3. The FIXS is designed to provide solar flare images at X-ray energies between 5 and 35 keV. Observations will be made on arcsecond size scales and subsecond time scales of the processes that modify the electron spectrum and the thermal distribution in flaring magnetic structures.

  1. Evaluation of passive avoidance learning and spatial memory in rats exposed to low levels of lead during specific periods of early brain development.

    Science.gov (United States)

    Rao Barkur, Rajashekar; Bairy, Laxminarayana K

    2015-01-01

    Widespread use of heavy metal lead (Pb) for various commercial purposes has resulted in the environmental contamination caused by this metal. The studies have shown a definite relationship between low level lead exposure during early brain development and deficit in children's cognitive functions. This study investigated the passive avoidance learning and spatial learning in male rat pups exposed to lead through their mothers during specific periods of early brain development. Experimental male rats were divided into 5 groups: i) the normal control group (NC) (N = 12) consisted of rat offspring born to mothers who were given normal drinking water throughout gestation and lactation, ii) the pre-gestation lead exposed group (PG) (N = 12) consisted of rat offspring, mothers of these rats had been exposed to 0.2% lead acetate in the drinking water for 1 month before conception, iii) the gestation lead exposed group (G) (N = 12) contained rat offspring born to mothers who had been exposed to 0.2% lead acetate in the drinking water throughout gestation, iv) the lactation lead exposed group (L) (N = 12) had rat offspring, mothers of these rats exposed to 0.2% lead acetate in the drinking water throughout lactation and v) the gestation and lactation lead exposed group (GL) (N = 12) contained rat offspring, mothers of these rats were exposed to 0.2% lead acetate throughout gestation and lactation. The study found deficit in passive avoidance learning in the G, L and GL groups of rats. Impairment in spatial learning was found in the PG, G, L and GL groups of rats. Interestingly, the study found that gestation period only and lactation period only lead exposure was sufficient to cause deficit in learning and memory in rats. The extent of memory impairment in the L group of rats was comparable with the GL group of rats. So it can be said that postnatal period of brain development is more sensitive to neurotoxicity compared to prenatal exposure. This work is available in Open

  2. Improving the Pipeline of Women in STEM Fields: Addressing Challenges in Instruction, Engagement, and Evaluation of an Aerospace Workshop Series for Girl Scouts

    Science.gov (United States)

    Sealfon, C. D.; Plummer, J. D.

    2012-08-01

    The Women in Aerospace and Technology Project (WATP) is a collaborative effort between the Girl Scouts of Eastern Pennsylvania, the American Helicopter Museum, Boeing Rotorcraft, Sikorsky Global Helicopters, Drexel University, West Chester University, and Arcadia University. The program aims to increase the representation of women in STEM (Science, Technology, Engineering, and Math) fields; the evaluation team identified a secondary goal to assess growth in participants' understanding of scientific inquiry. Girls, grades 4-12, were invited to join Girl Scout troops formed at the American Helicopter Museum to participate in a series of eight workshops on the physics and engineering of flight. Five college women majoring in physics and engineering were recruited as mentors for the girls. Lessons were written by local aerospace industry partners (including Boeing and Sikorsky); the mentors then taught the lessons and activities during the workshops. To evaluate the impact of this project, we collected data to answer two research questions: 1) In what ways does the program impact participants' attitudes towards science and interest in pursuing science as a career? 2) In what ways does the program impact participants' understanding of the nature of scientific inquiry? In this article we summarize results from two sources of data: before and after survey of attitudes about science and end-of-workshop informal questionnaires. Across the seven months of data collection, two challenges became apparent. First, our assessment goals, focusing on scientific interest and inquiry, seemed misaligned with the workshop curricula, which emphasized engineering and design. Secondly, there was little connection among activities within workshops and across the program.

  3. Effect of aeration rate, moisture content and composting period on availability of copper and lead during pig manure composting.

    Science.gov (United States)

    Shen, Yujun; Zhao, Lixin; Meng, Haibo; Hou, Yueqing; Zhou, Haibin; Wang, Fei; Cheng, Hongsheng; Liu, Hongbin

    2016-06-01

    Pollution by heavy metals, such as copper and lead, has become a limiting factor for the land application of faecal manures, such as pig manure. This study was conducted to investigate the influence of composting process parameters, including aeration rate, moisture content and composting period, on the distribution of heavy metal species during composting, and to select an optimal parameter for copper and lead inactivation. Results showed that the distribution ratios of exchangeable fractions of copper and lead had a bigger decrease under conditions of aeration rate, 0.1 m(3) min(-1) m(-3), an initial moisture content of 65% and composting period of 50 days. Suboptimal composting process conditions could lead to increased availability of heavy metals. Statistical analysis indicated that the aeration rate was the main factor affecting copper and lead inactivation, while the effects of moisture content and composting period were not significant. The rates of reduction of copper-exchangeable fractions and lead-exchangeable fractions were positively correlated with increased pH. The optimal parameters for reducing heavy metal bioavailability during pig manure composting were aeration rate, 0.1 m(3) min(-1) m(-3), initial moisture content, 65%, and composting period, 20 days. © The Author(s) 2016.

  4. Tactical Reconnaissance and Security for the Armor Battalion Commander: Is the Scout Platoon Combat Capable or Combat Ineffective?

    Science.gov (United States)

    1990-12-27

    reconnaissance force back to a heavy ele ,._.it capable of security missions and limited 10 reconnaissance. Vletnam continued the platoon’s emphasis on...College, Fort Leavenworth, KS, 30 November 1988 (CARL Ref. AOR215860). JouroaI ~ el Bacevich, LTC A. J. "Training Scouts." Armor, September 1987, pp. 37...Swanson, Major Steven G. " Bronco Nine Speaks His Mind." MIlitaryInteigence, April-June 1990, pp. 8- 10, 12. "The Bustle Rack." Armo,; March-April 1990

  5. Note: Optimal base-stock policy for the inventory system with periodic review, backorders and sequential lead times

    DEFF Research Database (Denmark)

    Johansen, Søren Glud; Thorstenson, Anders

    We show that well-known textbook formulae for determining the optimal base stock of the inventory system with continuous review and constant lead time can easily be extended to the case with periodic review and stochastic, sequential lead times. The provided performance measures and conditions...

  6. Search for Resonances Decaying to Dijet Final States at $\\sqrt{s} = 8$ TeV with Scouting Data

    CERN Document Server

    CMS Collaboration

    2015-01-01

    A search for resonances decaying to dijet final states is performed in pp collisions at a center-of-mass energy $\\sqrt{s}=8$ TeV. Using a loose online data selection and a reduced data format collected with a novel technique called $\\textit{data scouting}$, the search extends to low-mass values, testing previously unprobed low couplings. No evidence for a signal is found. The result is interpreted as upper limits on the production cross section as a function of the resonance mass. These limits are translated into an upper limit on the resonance coupling, allowing a comparison with results obtained in the same mass region at lower collision energies.

  7. Periodic and aperiodic flow patterns around an airfoil with leading-edge protuberances

    Science.gov (United States)

    Cai, Chang; Zuo, Zhigang; Maeda, Takao; Kamada, Yasunari; Li, Qing'an; Shimamoto, Kensei; Liu, Shuhong

    2017-11-01

    Recently leading-edge protuberances have attracted great attention as a passive method for separation control. In this paper, the effect of multiple leading-edge protuberances on the performance of a two-dimensional airfoil is investigated through experimental measurement of aerodynamic forces, surface tuft visualization, and numerical simulation. In contrast to the sharp stall of the baseline airfoil with large hysteresis effect during AOA (angle of attack) increasing and decreasing, the stall process of the modified airfoil with leading-edge protuberances is gentle and stable. Flow visualization revealed that the flow past each protuberance is periodic and symmetric at small AOAs. Streamwise vortices are generated on the shoulders of the protuberance, leading to a larger separation around the valley sections and a longer attachment along the peak sections. When some critical AOA is exceeded, aperiodic and asymmetric flow patterns occur on the protuberances at different spanwise positions, with leading-edge separation on some of the valley sections and non-stalled condition elsewhere. A combined mechanism, involving both the compartmentalization effect of the slender momentum-enhanced attached flows on the protuberance peaks and the downwash effect of the local stalled region with low circulation, is proposed to explain the generation of the aperiodic flow patterns. The influence of the number of protuberances is also investigated, which shows similar aperiodic flow patterns. The distance between the neighboring local stalled valley sections is found to be in the range of 4-7 times the protuberance wavelength. According to the proposed mechanism, it is speculated that the distance between the neighboring local stalled valley sections is inclined to increase with a smaller protuberance amplitude or at a larger AOA.

  8. POST TRAUMATIC STRESS DISORDER HANDLING THROUGH THE TRAUMA HEALING FOR SCOUT CARE

    Directory of Open Access Journals (Sweden)

    Muhammad Jufri

    2016-12-01

    Full Text Available The purpose of this activity is (1 to improve the knowledge of Scouting Care in Post Traumatic Stress Disordet overcome through Trauma Healing, (2 To improve the technical skills of Trauma Healing. The method used in this activity are: the percentage method, lecture and question and answer, discussion methods, methods of practice. The results of these activities are (1 there is an increased knowledge of participants in following the activities, especially in implementing and applying the theory and practice of PTSD to handling, from the data worksheet that was analyzed contained 94.5% of the questions as an evaluation materials may be answered by the participants. This indicates that the participant understands and is able to apply the techniques of PTSD very well in dealing with post-disaster stress. (2 Participants skillfully PTSD through psychotherapy techniques such as: deepbreating, relaxation techniques, storytelling / story telling, play therapy / role playing and games-games. From a practice several times, through observation through direct observation, illustrating that the participants could perform well in groups or individually

  9. Energy behaviours of northern California Girl Scouts and their families

    Energy Technology Data Exchange (ETDEWEB)

    Boudet, H; Ardoin, NM; Flora, J; Armel, KC; Desai, M; Robinson, TN

    2014-10-01

    Climate change is likely the most critical societal challenge to the futures of today's children. Mitigation will require a concerted effort to change household energy behaviour electricity use, transportation and food consumption patterns. A first step to changing behaviour is to better understand current behaviour and its intrapersonal (knowledge and attitudes), interpersonal (norms, communication and behaviour) and contextual (demographics and geography) correlates. To date, our understanding of the energy behaviours of children is limited. To begin to fill this gap, we report the results of a survey on the electricity, transportation and food-related energy behaviours of 323 fourth- and fifth-grade girls and their parents in 31 Girl Scout troops in Northern California. Our findings show positive attitudes and perceived norms toward energy-saving behaviours among child and adult respondents, but low or moderate levels of knowledge, communication, and behaviour, particularly for behaviours that require adult assistance. Girls' choices about electricity behaviours appear to be governed by intrapersonal and interpersonal influences, while transportation behaviour is constrained by geographic context. Food-related behaviour, particularly meat consumption, was not readily modelled. Policy and education-related implications for future interventions aimed at enhancing children's energy-saving behaviours are discussed. (C) 2014 Elsevier Ltd. All rights reserved.

  10. Lunar scout: A Project Artemis proposal

    Science.gov (United States)

    The results of a student project to design a lunar lander in the context of a specifically defined mission are presented. The Lunar Scout will be launched from Cape Canaveral, Florida onboard a Delta II launch vehicle. The Delta II will carry the lander and its payload to a 1367 km orbit. Once it reaches that altitude, a STAR 48A solid rocket motor will kick the spacecraft into a lunar trajectory. After burnout of the lunar insertion motor, it will be jettisoned from the spacecraft. The flight from the earth to the moon will take approximately 106.4 hours. During this time the battery, which was fully charged prior to launch, will provide all power to the spacecraft. Every hour, the spacecraft will use its sun sensors and star trackers to update its position, maintain some stabilization and relay it back to earth using the dipole antennas. At the start of its lunar trajectory, the spacecraft will fire one of its 1.5 N thrusters to spin in at a very small rate. The main reason for this is to prevent one side of the spacecraft from overheating in the sun. When the spacecraft nears the moon, it will orient itself for the main retro burn. At an altitude of 200 km, a 4400 N bipropellant liquid thruster will ignite to slow the spacecraft. During the burn, the radar altimeter will be turned on to guide the spacecraft. The main retro rocket will slow the lander to 10 m/s at an approximate altitude of 40 km above the moon. From there, the space craft will use four 4.5 N hydrazine vertical thrusters and 1.5 N horizontal thrusters to guide the spacecraft to a soft landing. Once on the ground, the lander will shutoff the radar and attitude control systems. After the debris from the impact has settled, the six solar panels will be deployed to begin recharging the batteries and to power up the payload. The feedhorn antenna will then rotate to fix itself on the earth. in that position for the spacecraft's lifetime. &The payload will then be activated

  11. Chemical compositions and lead isotope ratios of ancient lead-barium glasses found in Japan

    International Nuclear Information System (INIS)

    Yamasaki, Kazuo.

    1991-01-01

    Six lead-barium glasses found in the archaeological sites of the Yayoi period in the northern part of Kyushu, Japan were chemically analysed and their lead isotope ratios were determined. These data agreed with those of the glasses of the Pre-Han period found in China, suggesting the presence of possible trade between China in the Pre-Han Period (ca. fourth-third centuries B.C.) and Japan in the earlier Yayoi period (ca. first century B.C.). (author)

  12. Responses to Three USARIEM Job Analysis Questionnaires (JAQs) Conducted with Cavalry Scouts and Armor Crewmen (MOSs 19D and 19K)

    Science.gov (United States)

    2016-11-18

    gun for one fire command 56 24 Boxes of rounds loaded for the .50 Cal Machine Gun on an Abrams Tank 56 25 Mean estimates of time spent by 19Ds...Number of rounds loaded for one fire command 55 22 Total boxes of rounds loaded for .50 cal machine gun on an Abrams tank 56 23 Number of Soldiers...and 19K MOSs, respectively). A total o f 8,580 Army calvary scouts and 6,613 armor crewmen in the USA Army as of May or June of 2014 were invited

  13. Solids Accumulation Scouting Studies

    Energy Technology Data Exchange (ETDEWEB)

    Duignan, M. R.; Steeper, T. J.; Steimke, J. L.

    2012-09-26

    The objective of Solids Accumulation activities was to perform scaled testing to understand the behavior of remaining solids in a Double Shell Tank (DST), specifically AW-105, at Hanford during multiple fill, mix, and transfer operations. It is important to know if fissionable materials can concentrate when waste is transferred from staging tanks prior to feeding waste treatment plants. Specifically, there is a concern that large, dense particles containing plutonium could accumulate in poorly mixed regions of a blend tank heel for tanks that employ mixing jet pumps. At the request of the DOE Hanford Tank Operations Contractor, Washington River Protection Solutions, the Engineering Development Laboratory of the Savannah River National Laboratory performed a scouting study in a 1/22-scale model of a waste staging tank to investigate this concern and to develop measurement techniques that could be applied in a more extensive study at a larger scale. Simulated waste tank solids: Gibbsite, Zirconia, Sand, and Stainless Steel, with stainless steel particles representing the heavier particles, e.g., plutonium, and supernatant were charged to the test tank and rotating liquid jets were used to mix most of the solids while the simulant was pumped out. Subsequently, the volume and shape of the mounds of residual solids and the spatial concentration profiles for the surrogate for heavier particles were measured. Several techniques were developed and equipment designed to accomplish the measurements needed and they included: 1. Magnetic particle separator to remove simulant stainless steel solids. A device was designed and built to capture these solids, which represent the heavier solids during a waste transfer from a staging tank. 2. Photographic equipment to determine the volume of the solids mounds. The mounds were photographed as they were exposed at different tank waste levels to develop a composite of topographical areas. 3. Laser rangefinders to determine the volume of

  14. Maintained intentional weight loss reduces cardiovascular outcomes: results from the Sibutramine Cardiovascular OUTcomes (SCOUT) trial.

    Science.gov (United States)

    Caterson, I D; Finer, N; Coutinho, W; Van Gaal, L F; Maggioni, A P; Torp-Pedersen, C; Sharma, A M; Legler, U F; Shepherd, G M; Rode, R A; Perdok, R J; Renz, C L; James, W P T

    2012-06-01

    The Sibutramine Cardiovascular OUTcomes trial showed that sibutramine produced greater mean weight loss than placebo but increased cardiovascular morbidity but not mortality. The relationship between 12-month weight loss and subsequent cardiovascular outcomes is explored. Overweight/obese subjects (N = 10 744), ≥55 years with cardiovascular disease and/or type 2 diabetes mellitus, received sibutramine plus weight management during a 6-week Lead-in Period before randomization to continue sibutramine (N = 4906) or to receive placebo (N = 4898). The primary endpoint was the time from randomization to first occurrence of a primary outcome event (non-fatal myocardial infarction, non-fatal stroke, resuscitated cardiac arrest or cardiovascular death). For the total population, mean weight change during Lead-in Period (sibutramine) was -2.54 kg. Post-randomization, mean total weight change to Month 12 was -4.18 kg (sibutramine) or -1.87 kg (placebo). Degree of weight loss during Lead-in Period or through Month 12 was associated with a progressive reduction in risk for the total population in primary outcome events and cardiovascular mortality over the 5-year assessment. Although more events occurred in the randomized sibutramine group, on an average, a modest weight loss of approximately 3 kg achieved in the Lead-in Period appeared to offset this increased event rate. Moderate weight loss (3-10 kg) reduced cardiovascular deaths in those with severe, moderate or mild cardiovascular disease. Modest weight loss over short-term (6 weeks) and longer-term (6-12 months) periods is associated with reduction in subsequent cardiovascular mortality for the following 4-5 years even in those with pre-existing cardiovascular disease. While the sibutramine group experienced more primary outcome events than the placebo group, greater weight loss reduced overall risk of these occurring in both groups. © 2011 Blackwell Publishing Ltd.

  15. Ingestion of lead from ammunition and lead concentrations in white-tailed sea eagles (Haliaeetus albicilla) in Sweden

    International Nuclear Information System (INIS)

    Helander, B.; Axelsson, J.; Borg, H.; Holm, K.; Bignert, A.

    2009-01-01

    In this study we show for the first time that lead poisoning from ammunition is a significant mortality factor for white-tailed sea eagle (WSE) (Haliaeetus albicilla) in Sweden. We analyzed 118 WSEs collected between 1981 and 2004 from which both liver and kidney samples could be taken. A total of 22% of all eagles examined had elevated (> 6 μg/g d.w.) lead concentrations, indicating exposure to leaded ammunition, and 14% of the individuals had either liver or kidney lead concentrations diagnostic of lethal lead poisoning (> 20 μg/g d.w.). Lead concentrations in liver and kidney were significantly correlated. In individuals with lead levels 20 μg/g, concentrations were significantly higher in liver. The lead isotope ratios indicate that the source of lead in individuals with lethal concentrations is different from that of individuals exhibiting background concentrations of lead ( 10 times higher than concentrations reported for Baltic fish from the same time period. In contrast to other biota there was no decrease in lead concentrations in WSE over the study period. The proportion of lead poisoned WSE remained unchanged over the study period, including two years after a partial ban of lead shot was enforced in 2002 for shallow wetlands. The use of lead in ammunition poses a threat to all raptors potentially feeding on shot game or offal. The removal of offal from shot game and alternatives to leaded ammunition needs to be implemented in order to prevent mortality from lead in raptors and scavengers.

  16. Periodic capacity management under a lead-time performance constraint

    NARCIS (Netherlands)

    Büyükkaramikli, N.C.; Bertrand, J.W.M.; Ooijen, van H.P.G.

    2013-01-01

    In this paper, we study a production system that operates under a lead-time performance constraint which guarantees the completion of an order before a pre-determined lead-time with a certain probability. The demand arrival times and the service requirements for the orders are random. To reduce the

  17. Temporal stability of blood lead concentrations in adults exposed only to environmental lead

    Energy Technology Data Exchange (ETDEWEB)

    Delves, H T; Sherlock, J C; Quinn, M J

    1984-08-01

    The temporal stability of blood lead concentrations of 21 health adults (14 men and 7 women) exposed only to environmental lead was assessed by analysis of 253 blood specimens collected serially over periods from 7 to 11 months. The women had lower blood lead concentrations (mean 8.5, range 7.4-10.8 micrograms/100 ml) than did the men (mean 12.2, range 8.6-15.8 micrograms/100 ml). These are within the expected ranges for non-occupationally exposed persons. Blood lead concentrations in the serial specimens from both men and women changed very little over the study period, with standard deviations of less than 0.5 micrograms/100 ml for the majority of individual mean concentrations: for all except low subjects the standard deviations were less than 0.8 micrograms/100 ml. Two subjects showed significant changes in blood lead concentrations during the study. A temporary increase in oral lead intake was identified for one of these subjects. In the absence of substantial changes in lead exposure blood lead levels in adults are remarkably stable and for their environmental monitoring a single blood lead concentration is an excellent biological indicator.

  18. Ingestion of lead from ammunition and lead concentrations in white-tailed sea eagles (Haliaeetus albicilla) in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Helander, B., E-mail: bjorn.helander@nrm.se [Department of Contaminant Research, Swedish Museum of Natural History, Box 50007, SE-104 05 Stockholm (Sweden); Axelsson, J., E-mail: jeanette.axelsson@hgen.slu.se [Department of Environmental Toxicology, Evolutionary Biology Centre, Uppsala University, SE-752 36 Uppsala (Sweden); Borg, H., E-mail: hans.borg@itm.su.se [Department of Applied Environmental Science/ITM, Stockholm University, SE-106 91 Stockholm (Sweden); Holm, K. [Department of Applied Environmental Science/ITM, Stockholm University, SE-106 91 Stockholm (Sweden); Bignert, A., E-mail: anders.bignert@nrm.se [Department of Contaminant Research, Swedish Museum of Natural History, Box 50007, SE-104 05 Stockholm (Sweden)

    2009-10-15

    In this study we show for the first time that lead poisoning from ammunition is a significant mortality factor for white-tailed sea eagle (WSE) (Haliaeetus albicilla) in Sweden. We analyzed 118 WSEs collected between 1981 and 2004 from which both liver and kidney samples could be taken. A total of 22% of all eagles examined had elevated (> 6 {mu}g/g d.w.) lead concentrations, indicating exposure to leaded ammunition, and 14% of the individuals had either liver or kidney lead concentrations diagnostic of lethal lead poisoning (> 20 {mu}g/g d.w.). Lead concentrations in liver and kidney were significantly correlated. In individuals with lead levels < 6 {mu}g/g, concentrations were significantly higher in kidney than in liver; in individuals with lead levels > 20 {mu}g/g, concentrations were significantly higher in liver. The lead isotope ratios indicate that the source of lead in individuals with lethal concentrations is different from that of individuals exhibiting background concentrations of lead (< 6 {mu}g/g d.w.) There were no significant sex or age differences in lead concentrations. A study from the Baltic reported in principle no biomagnification of lead, but background lead concentrations in WSE liver in this study were still four to > 10 times higher than concentrations reported for Baltic fish from the same time period. In contrast to other biota there was no decrease in lead concentrations in WSE over the study period. The proportion of lead poisoned WSE remained unchanged over the study period, including two years after a partial ban of lead shot was enforced in 2002 for shallow wetlands. The use of lead in ammunition poses a threat to all raptors potentially feeding on shot game or offal. The removal of offal from shot game and alternatives to leaded ammunition needs to be implemented in order to prevent mortality from lead in raptors and scavengers.

  19. Lead exposure from lead pellets: age-related accumulation in mute swans

    Energy Technology Data Exchange (ETDEWEB)

    Eskildsen, J.; Grandjean, P.

    1984-05-01

    In a cross-sectional study of adult swans and their successfully fledged young in Ringkobing Fjord, West Jutland, Denmark, 128 venous blood samples were taken during the moulting period and analyzed for lead. While the juveniles generally showed blood lead levels below 15 micrograms/100 ml (median, 11 micrograms/100 ml), the values were significantly higher in adults (median, 25 micrograms/100 ml). Adult females showed slightly higher levels than did adult males. None of the birds examined showed signs of acute lead toxicity, and increased blood levels in adults may reflect increased lead body burdens from previous ingestion of lead shot as gizzard stones.

  20. Lead Exposure Impairs Hippocampus Related Learning and Memory by Altering Synaptic Plasticity and Morphology During Juvenile Period.

    Science.gov (United States)

    Wang, Tao; Guan, Rui-Li; Liu, Ming-Chao; Shen, Xue-Feng; Chen, Jing Yuan; Zhao, Ming-Gao; Luo, Wen-Jing

    2016-08-01

    Lead (Pb) is an environmental neurotoxic metal. Pb exposure may cause neurobehavioral changes, such as learning and memory impairment, and adolescence violence among children. Previous animal models have largely focused on the effects of Pb exposure during early development (from gestation to lactation period) on neurobehavior. In this study, we exposed Sprague-Dawley rats during the juvenile stage (from juvenile period to adult period). We investigated the synaptic function and structural changes and the relationship of these changes to neurobehavioral deficits in adult rats. Our results showed that juvenile Pb exposure caused fear-conditioned memory impairment and anxiety-like behavior, but locomotion and pain behavior were indistinguishable from the controls. Electrophysiological studies showed that long-term potentiation induction was affected in Pb-exposed rats, and this was probably due to excitatory synaptic transmission impairment in Pb-exposed rats. We found that NMDA and AMPA receptor-mediated current was inhibited, whereas the GABA synaptic transmission was normal in Pb-exposed rats. NR2A and phosphorylated GluR1 expression decreased. Moreover, morphological studies showed that density of dendritic spines declined by about 20 % in the Pb-treated group. The spine showed an immature form in Pb-exposed rats, as indicated by spine size measurements. However, the length and arborization of dendrites were unchanged. Our results suggested that juvenile Pb exposure in rats is associated with alterations in the glutamate receptor, which caused synaptic functional and morphological changes in hippocampal CA1 pyramidal neurons, thereby leading to behavioral changes.

  1. Lead and zinc removal with storage period in porous asphalt ...

    African Journals Online (AJOL)

    2013-03-01

    Mar 1, 2013 ... total suspended sediments (TSS)), nutrients (e.g., total Kjeldahl nitrogen (TKN)), oil ... (e.g., lead, copper and zinc), are carried by stormwater runoff ..... The essential mineral of limestone ..... kinetics of basalt–water interaction.

  2. Association between the mean CT value on a scout view and the dependent mA selection method in coronary artery imaging on 64-row multi-slice spiral CT

    International Nuclear Information System (INIS)

    Gao Jianhua; Li Tao; Mi Fengtang; Li Na; Cui Ying; Dai Ruping; Li Jianying

    2009-01-01

    Objective: To characterize the association between the mean CT value on a scout view and the dependent mA selection method, and to evaluate the clinical value of a mA selection method based on scout view mean CT value in obtaining individualized scan protocol and consistent image quality for patient population on 64-row MSCT CT coronary angiography (CTCA). Methods: One hundred patients (group A) underwent CTCA consecutively using standard protocol with a fixed mA. The mean CT value of a fixed ROI (region of interest) from the scout AP view and the CTCA image noise (standard deviation on the root of ascending aorta) were measured. The correlation between CT values and noise was studied to establish a formula and a list to determine the required mA for obtaining a consistent CTCA image noise based on the measured SV CT value. Another 100 patients (group B) were scanned using the same parameters as group A except the mA and the CT value was also measured. The mA was determined by the list established previously. The CTCA image quality (IQ) as well as the image noise (IN) and the effective dose (ED) from the two groups were statistically analyzed using t-test. The CT findings for the 32 patients in the group B were also compared with the selective coronary angiography (SCA) results. The sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of CTCA for detection of significant stenosis were obtained. Results: The formula between the required mA and the CT value was: XmA=FmA x [(K 1 x CTscout + C 1 )/INa] 2 . The CTCA images in B group had statistically higher IN (27.66±2.57, 22.22±4.17, t=11.33, P=0.000), but no statistical difference between IQ scores for the two groups (3.29±0.66, 3.37±0.67, t=0.009, P=0.990), and ED [(8.72±2.51) versus (12.53±0.90) mSv] was 30% lower for the B group (P<0.01). For the 32 patients in the B group who had SCA, the CTCA sensitivity, specificity, positive predictive value, negative

  3. His Majesty Carl XVI Gustav, King of Sweden, Honorary President of the World Scout Foundation, and about 80 fellows, on the occasion of the 48th World Baden-Powell Fellowship Event on Saturday, 18th September 2004

    CERN Multimedia

    Patrice Loiez

    2004-01-01

    His Majesty Carl XVI Gustav, King of Sweden, Honorary President of the World Scout Foundation, and about 80 fellows, on the occasion of the 48th World Baden-Powell Fellowship Event on Saturday, 18th September 2004

  4. Estimation of gadolinium-induced T1-shortening with measurement of simple signal intensity ratio between the cochlea and brain parenchyma on 3D-FLAIR. Correlation with T1 measurement by TI scout sequence

    International Nuclear Information System (INIS)

    Naganawa, Shinji; Ishihara, Shunichi; Iwano, Shingo; Kawai, Hisashi; Sone, Michihiko; Nakashima, Tsutomu

    2010-01-01

    The purpose of this study was to T 1 -shortening of labyrinthine fluid on 3-dimensional fluid-attenuated inversion recovery (3D-FLAIR) has been reported in many inner ear disorders. Although semi-quantitative assessment by simple signal intensity ratio between cochlear fluid and brain tissue has been tried, its feasibility using a multi-channel phased-array head coil with an inherently inhomogenous sensitivity distribution has not been fully evaluated. We evaluated the feasibility of measuring simple signal intensity ratio by correlating rapid T 1 measurements using an inversion time (TI) scout sequence. We evaluated 10 patients with Meniere's disease and 4 patients with sudden deafness. Nine of the patients with Meniere's disease received a unilateral intratympanic injection of gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA); the tenth patient received bilateral injections. The 4 patients with sudden deafness received a double-dose intravenous injection. Magnetic resonance (MR) images were obtained 24 hours after intratympanic injections and 4 hours after intravenous injections at 3 tesla using a 32-channel head coil. We measured the ratio (CM ratio) between the signal intensity of the perilymph in the cochlea (C) and that of the medulla oblongata (M) and correlated it with the null-point inversion time (TI null ) obtained with the TI scout sequence. The TI scout consisted of 85 images obtained with TI values between 132.5 and 3087.5 ms at increments of 37.5 ms. The correlation coefficient between TI null and the natural logarithm of the CM ratio was -0.88 (P<0.01). There was significant negative linear correlation. Measurement of the simple signal intensity ratio between the cochlea and the medulla can be used for semi-quantitative analysis of 3D-FLAIR. The results of this study may facilitate clinical research of inner-ear disease using 3D-FLAIR. (author)

  5. Lead poisoning in dogs

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, M R; Lewis, G

    1963-08-03

    Within a short period, 14 cases of lead poisoning in the dogs have been encountered. A detailed record appears justified as no published reference can be found to this condition occurring in Britain and because reports from other countries stress the similarity of the clinical manifestations of lead poisoning to those of the common infections of the dog. Five of the 14 clinical cases of lead poisoning are described. The available literature is reviewed and the diagnosis and significance of the condition discussed. 19 references, 2 tables.

  6. Frequency and changes in trends of leading risk factors of coronary heart disease in women in the city of Novi Sad during a 20-year period

    Directory of Open Access Journals (Sweden)

    Rakić Dušica

    2012-01-01

    Full Text Available Backround/Aim. From 1984 to 2004 the city of Novi Sad participated through its Health Center “Novi Sad” in the international Multinational MONItoring of Trends and Determinants in CArdiovascular Disease (MONICA project, as one of the 38 research centers in 21 countries around the world. The aim of this study was to determine frequency and changes of trends in leading risk factors of coronary heart disease (CHD and to analyze the previous trend of movement of coronary event in women in Novi Sad during a 20- year period. Methods. In 2004, the fourth survey within MONICA project was conducted in the city of Novi Sad. The representative sample included 1,041 women between the age of 25 and 74. The prevalence of risk factors in CHD such as smoking, high blood pressure, elevated blood cholesterol, elevated blood glucose and obesity was determined. Also, indicators of risk factors and rates of coronary events in women were compared with the results from MONICA project obtained in previous three screens, as well as with the results from other research centres. χ2-test, linear trend and correlartion coefficient were used in statistical analysis of results obtained. Results. It was observed that during a 20-year period covered by the study, the prevalence of the leading risk factors for the development of CHD in the surveyed women was significantly increasing and in positive correlation with the values of linear trend. Also, the increase of morbidity rates and mortality rates of coronary event were in positive correlation. The decrease was only recorded in the period from 1985-1989 (the implementation of the intervention programme. Conclusion. Upon analysing the increase in prevalence of leading risk factors of CHD and significant increase in the rates of coronary event, we can conclude that health status of women in Novi Sad during a 20-year period was deteriorating.

  7. Flexibility and torsional behaviour of rotary nickel-titanium PathFile, RaCe ISO 10, Scout RaCe and stainless steel K-File hand instruments.

    Science.gov (United States)

    Nakagawa, R K L; Alves, J L; Buono, V T L; Bahia, M G A

    2014-03-01

    To assess and compare the flexibility and torsional resistance of PathFile, RaCe ISO 10 and Scout RaCe instruments in relation to stainless steel K-File hand instruments. Rotary PathFile (sizes 13, 16 and 19; .02 taper), Race ISO 10 (size 10; 0.02, 0.04 and 0.06 tapers), Scout RaCe (sizes 10, 15 and 20; 0.02 taper) and hand K-File (sizes 10, 15 and 20; 0.02 taper) instruments were evaluated. Alloy chemical composition, phases present and transformation temperatures were determined for the NiTi instruments. For all instruments, diameters at each millimetre from the tip as well as cross-sectional areas at 3 mm from the tip were measured based on ANSI/ADA Specification No. 101 using image analysis software. Resistance to bending and torsional resistance were determined according to specification ISO 3630-1. Vickers microhardness measurements were also taken in all instruments to assess their strength. Data were analysed using analysis of variance (α = 0.05). The alloys used in the manufacture of the three types of NiTi instruments had approximately the same chemical composition, but the PathFile instruments had a higher Af transformation temperature and contained a small amount of B19' martensite. All instruments had diameter values within the standard tolerance. The bending and torsional resistance values were significantly increased relative to the instrument diameter and cross-sectional area. PathFile instruments were the most flexible and the least torque resistant, whilst the stainless steel instruments were the least flexible although they were more torque resistant than the NiTi instruments. © 2013 International Endodontic Journal. Published by John Wiley & Sons Ltd.

  8. Search for narrow resonances in dijet final states at $\\sqrt{s}= $ 8 TeV with the novel CMS technique of data scouting

    CERN Document Server

    Khachatryan, Vardan; Tumasyan, Armen; Adam, Wolfgang; Aşılar, Ece; Bergauer, Thomas; Brandstetter, Johannes; Brondolin, Erica; Dragicevic, Marko; Erö, Janos; Flechl, Martin; Friedl, Markus; Fruehwirth, Rudolf; Ghete, Vasile Mihai; Hartl, Christian; Hörmann, Natascha; Hrubec, Josef; Jeitler, Manfred; König, Axel; Krätschmer, Ilse; Liko, Dietrich; Matsushita, Takashi; Mikulec, Ivan; Rabady, Dinyar; Rad, Navid; Rahbaran, Babak; Rohringer, Herbert; Schieck, Jochen; Strauss, Josef; Treberer-Treberspurg, Wolfgang; Waltenberger, Wolfgang; Wulz, Claudia-Elisabeth; Mossolov, Vladimir; Shumeiko, Nikolai; Suarez Gonzalez, Juan; Alderweireldt, Sara; De Wolf, Eddi A; Janssen, Xavier; Knutsson, Albert; Lauwers, Jasper; Van De Klundert, Merijn; Van Haevermaet, Hans; Van Mechelen, Pierre; Van Remortel, Nick; Van Spilbeeck, Alex; Abu Zeid, Shimaa; Blekman, Freya; D'Hondt, Jorgen; Daci, Nadir; De Bruyn, Isabelle; Deroover, Kevin; Heracleous, Natalie; Lowette, Steven; Moortgat, Seth; Moreels, Lieselotte; Olbrechts, Annik; Python, Quentin; Tavernier, Stefaan; Van Doninck, Walter; Van Mulders, Petra; Van Parijs, Isis; Brun, Hugues; Caillol, Cécile; Clerbaux, Barbara; De Lentdecker, Gilles; Delannoy, Hugo; Fasanella, Giuseppe; Favart, Laurent; Goldouzian, Reza; Grebenyuk, Anastasia; Karapostoli, Georgia; Lenzi, Thomas; Léonard, Alexandre; Luetic, Jelena; Maerschalk, Thierry; Marinov, Andrey; Randle-conde, Aidan; Seva, Tomislav; Vander Velde, Catherine; Vanlaer, Pascal; Yonamine, Ryo; Zenoni, Florian; Zhang, Fengwangdong; Cimmino, Anna; Cornelis, Tom; Dobur, Didar; Fagot, Alexis; Garcia, Guillaume; Gul, Muhammad; Mccartin, Joseph; Poyraz, Deniz; Salva Diblen, Sinem; Schöfbeck, Robert; Tytgat, Michael; Van Driessche, Ward; Yazgan, Efe; Zaganidis, Nicolas; Beluffi, Camille; Bondu, Olivier; Brochet, Sébastien; Bruno, Giacomo; Caudron, Adrien; Ceard, Ludivine; De Visscher, Simon; Delaere, Christophe; Delcourt, Martin; Forthomme, Laurent; Francois, Brieuc; Giammanco, Andrea; Jafari, Abideh; Jez, Pavel; Komm, Matthias; Lemaitre, Vincent; Magitteri, Alessio; Mertens, Alexandre; Musich, Marco; Nuttens, Claude; Piotrzkowski, Krzysztof; Quertenmont, Loic; Selvaggi, Michele; Vidal Marono, Miguel; Wertz, Sébastien; Beliy, Nikita; Aldá Júnior, Walter Luiz; Alves, Fábio Lúcio; Alves, Gilvan; Brito, Lucas; Correa Martins Junior, Marcos; Hensel, Carsten; Moraes, Arthur; Pol, Maria Elena; Rebello Teles, Patricia; Belchior Batista Das Chagas, Ewerton; Carvalho, Wagner; Chinellato, Jose; Custódio, Analu; Melo Da Costa, Eliza; Da Silveira, Gustavo Gil; De Jesus Damiao, Dilson; De Oliveira Martins, Carley; Fonseca De Souza, Sandro; Huertas Guativa, Lina Milena; Malbouisson, Helena; Matos Figueiredo, Diego; Mora Herrera, Clemencia; Mundim, Luiz; Nogima, Helio; Prado Da Silva, Wanda Lucia; Santoro, Alberto; Sznajder, Andre; Tonelli Manganote, Edmilson José; Vilela Pereira, Antonio; Ahuja, Sudha; Bernardes, Cesar Augusto; Dogra, Sunil; Tomei, Thiago; De Moraes Gregores, Eduardo; Mercadante, Pedro G; Moon, Chang-Seong; Novaes, Sergio F; Padula, Sandra; Romero Abad, David; Ruiz Vargas, José Cupertino; Aleksandrov, Aleksandar; Hadjiiska, Roumyana; Iaydjiev, Plamen; Rodozov, Mircho; Stoykova, Stefka; Sultanov, Georgi; Vutova, Mariana; Dimitrov, Anton; Glushkov, Ivan; Litov, Leander; Pavlov, Borislav; Petkov, Peicho; Fang, Wenxing; Ahmad, Muhammad; Bian, Jian-Guo; Chen, Guo-Ming; Chen, He-Sheng; Chen, Mingshui; Chen, Ye; Cheng, Tongguang; Du, Ran; Jiang, Chun-Hua; Leggat, Duncan; Liu, Zhenan; Romeo, Francesco; Shaheen, Sarmad Masood; Spiezia, Aniello; Tao, Junquan; Wang, Chunjie; Wang, Zheng; Zhang, Huaqiao; Zhao, Jingzhou; Asawatangtrakuldee, Chayanit; Ban, Yong; Li, Qiang; Liu, Shuai; Mao, Yajun; Qian, Si-Jin; Wang, Dayong; Xu, Zijun; Avila, Carlos; Cabrera, Andrés; Chaparro Sierra, Luisa Fernanda; Florez, Carlos; Gomez, Juan Pablo; González Hernández, Carlos Felipe; Ruiz Alvarez, José David; Sanabria, Juan Carlos; Godinovic, Nikola; Lelas, Damir; Puljak, Ivica; Ribeiro Cipriano, Pedro M; Antunovic, Zeljko; Kovac, Marko; Brigljevic, Vuko; Ferencek, Dinko; Kadija, Kreso; Micanovic, Sasa; Sudic, Lucija; Attikis, Alexandros; Mavromanolakis, Georgios; Mousa, Jehad; Nicolaou, Charalambos; Ptochos, Fotios; Razis, Panos A; Rykaczewski, Hans; Finger, Miroslav; Finger Jr, Michael; Carrera Jarrin, Edgar; Elgammal, Sherif; Mohamed, Amr; Mohammed, Yasser; Salama, Elsayed; Calpas, Betty; Kadastik, Mario; Murumaa, Marion; Perrini, Lucia; Raidal, Martti; Tiko, Andres; Veelken, Christian; Eerola, Paula; Pekkanen, Juska; Voutilainen, Mikko; Härkönen, Jaakko; Karimäki, Veikko; Kinnunen, Ritva; Lampén, Tapio; Lassila-Perini, Kati; Lehti, Sami; Lindén, Tomas; Luukka, Panja-Riina; Peltola, Timo; Tuominiemi, Jorma; Tuovinen, Esa; Wendland, Lauri; Talvitie, Joonas; Tuuva, Tuure; Besancon, Marc; Couderc, Fabrice; Dejardin, Marc; Denegri, Daniel; Fabbro, Bernard; Faure, Jean-Louis; Favaro, Carlotta; Ferri, Federico; Ganjour, Serguei; Ghosh, Saranya; Givernaud, Alain; Gras, Philippe; Hamel de Monchenault, Gautier; Jarry, Patrick; Kucher, Inna; Locci, Elizabeth; Machet, Martina; Malcles, Julie; Rander, John; Rosowsky, André; Titov, Maksym; Zghiche, Amina; Abdulsalam, Abdulla; Antropov, Iurii; Baffioni, Stephanie; Beaudette, Florian; Busson, Philippe; Cadamuro, Luca; Chapon, Emilien; Charlot, Claude; Davignon, Olivier; Granier de Cassagnac, Raphael; Jo, Mihee; Lisniak, Stanislav; Miné, Philippe; Naranjo, Ivo Nicolas; Nguyen, Matthew; Ochando, Christophe; Ortona, Giacomo; Paganini, Pascal; Pigard, Philipp; Regnard, Simon; Salerno, Roberto; Sirois, Yves; Strebler, Thomas; Yilmaz, Yetkin; Zabi, Alexandre; Agram, Jean-Laurent; Andrea, Jeremy; Aubin, Alexandre; Bloch, Daniel; Brom, Jean-Marie; Buttignol, Michael; Chabert, Eric Christian; Chanon, Nicolas; Collard, Caroline; Conte, Eric; Coubez, Xavier; Fontaine, Jean-Charles; Gelé, Denis; Goerlach, Ulrich; Le Bihan, Anne-Catherine; Merlin, Jeremie Alexandre; Skovpen, Kirill; Van Hove, Pierre; Gadrat, Sébastien; Beauceron, Stephanie; Bernet, Colin; Boudoul, Gaelle; Bouvier, Elvire; Carrillo Montoya, Camilo Andres; Chierici, Roberto; Contardo, Didier; Courbon, Benoit; Depasse, Pierre; El Mamouni, Houmani; Fan, Jiawei; Fay, Jean; Gascon, Susan; Gouzevitch, Maxime; Grenier, Gérald; Ille, Bernard; Lagarde, Francois; Laktineh, Imad Baptiste; Lethuillier, Morgan; Mirabito, Laurent; Pequegnot, Anne-Laure; Perries, Stephane; Popov, Andrey; Sabes, David; Sordini, Viola; Vander Donckt, Muriel; Verdier, Patrice; Viret, Sébastien; Toriashvili, Tengizi; Lomidze, David; Autermann, Christian; Beranek, Sarah; Feld, Lutz; Heister, Arno; Kiesel, Maximilian Knut; Klein, Katja; Lipinski, Martin; Ostapchuk, Andrey; Preuten, Marius; Raupach, Frank; Schael, Stefan; Schomakers, Christian; Schulte, Jan-Frederik; Schulz, Johannes; Verlage, Tobias; Weber, Hendrik; Zhukov, Valery; Brodski, Michael; Dietz-Laursonn, Erik; Duchardt, Deborah; Endres, Matthias; Erdmann, Martin; Erdweg, Sören; Esch, Thomas; Fischer, Robert; Güth, Andreas; Hebbeker, Thomas; Heidemann, Carsten; Hoepfner, Kerstin; Knutzen, Simon; Merschmeyer, Markus; Meyer, Arnd; Millet, Philipp; Mukherjee, Swagata; Olschewski, Mark; Padeken, Klaas; Papacz, Paul; Pook, Tobias; Radziej, Markus; Reithler, Hans; Rieger, Marcel; Scheuch, Florian; Sonnenschein, Lars; Teyssier, Daniel; Thüer, Sebastian; Cherepanov, Vladimir; Erdogan, Yusuf; Flügge, Günter; Hoehle, Felix; Kargoll, Bastian; Kress, Thomas; Künsken, Andreas; Lingemann, Joschka; Nehrkorn, Alexander; Nowack, Andreas; Nugent, Ian Michael; Pistone, Claudia; Pooth, Oliver; Stahl, Achim; Aldaya Martin, Maria; Asin, Ivan; Beernaert, Kelly; Behnke, Olaf; Behrens, Ulf; Bin Anuar, Afiq Aizuddin; Borras, Kerstin; Campbell, Alan; Connor, Patrick; Contreras-Campana, Christian; Costanza, Francesco; Diez Pardos, Carmen; Dolinska, Ganna; Eckerlin, Guenter; Eckstein, Doris; Eichhorn, Thomas; Gallo, Elisabetta; Garay Garcia, Jasone; Geiser, Achim; Gizhko, Andrii; Grados Luyando, Juan Manuel; Gunnellini, Paolo; Harb, Ali; Hauk, Johannes; Hempel, Maria; Jung, Hannes; Kalogeropoulos, Alexis; Karacheban, Olena; Kasemann, Matthias; Keaveney, James; Kieseler, Jan; Kleinwort, Claus; Korol, Ievgen; Lange, Wolfgang; Lelek, Aleksandra; Leonard, Jessica; Lipka, Katerina; Lobanov, Artur; Lohmann, Wolfgang; Mankel, Rainer; Melzer-Pellmann, Isabell-Alissandra; Meyer, Andreas Bernhard; Mittag, Gregor; Mnich, Joachim; Mussgiller, Andreas; Ntomari, Eleni; Pitzl, Daniel; Placakyte, Ringaile; Raspereza, Alexei; Roland, Benoit; Sahin, Mehmet Özgür; Saxena, Pooja; Schoerner-Sadenius, Thomas; Seitz, Claudia; Spannagel, Simon; Stefaniuk, Nazar; Trippkewitz, Karim Damun; Van Onsem, Gerrit Patrick; Walsh, Roberval; Wissing, Christoph; Blobel, Volker; Centis Vignali, Matteo; Draeger, Arne-Rasmus; Dreyer, Torben; Erfle, Joachim; Garutti, Erika; Goebel, Kristin; Gonzalez, Daniel; Görner, Martin; Haller, Johannes; Hoffmann, Malte; Höing, Rebekka Sophie; Junkes, Alexandra; Klanner, Robert; Kogler, Roman; Kovalchuk, Nataliia; Lapsien, Tobias; Lenz, Teresa; Marchesini, Ivan; Marconi, Daniele; Meyer, Mareike; Niedziela, Marek; Nowatschin, Dominik; Ott, Jochen; Pantaleo, Felice; Peiffer, Thomas; Perieanu, Adrian; Pietsch, Niklas; Poehlsen, Jennifer; Sander, Christian; Scharf, Christian; Schleper, Peter; Schlieckau, Eike; Schmidt, Alexander; Schumann, Svenja; Schwandt, Joern; Stadie, Hartmut; Steinbrück, Georg; Stober, Fred-Markus Helmut; Stöver, Marc; Tholen, Heiner; Troendle, Daniel; Usai, Emanuele; Vanelderen, Lukas; Vanhoefer, Annika; Vormwald, Benedikt; Barth, Christian; Baus, Colin; Berger, Joram; Butz, Erik; Chwalek, Thorsten; Colombo, Fabio; De Boer, Wim; Dierlamm, Alexander; Fink, Simon; Friese, Raphael; Giffels, Manuel; Gilbert, Andrew; Haitz, Dominik; Hartmann, Frank; Heindl, Stefan Michael; Husemann, Ulrich; Katkov, Igor; Kornmayer, Andreas; Lobelle Pardo, Patricia; Maier, Benedikt; Mildner, Hannes; Mozer, Matthias Ulrich; Müller, Thomas; Müller, Thomas; Plagge, Michael; Quast, Gunter; Rabbertz, Klaus; Röcker, Steffen; Roscher, Frank; Schröder, Matthias; Sieber, Georg; Simonis, Hans-Jürgen; Ulrich, Ralf; Wagner-Kuhr, Jeannine; Wayand, Stefan; Weber, Marc; Weiler, Thomas; Williamson, Shawn; Wöhrmann, Clemens; Wolf, Roger; Anagnostou, Georgios; Daskalakis, Georgios; Geralis, Theodoros; Giakoumopoulou, Viktoria Athina; Kyriakis, Aristotelis; Loukas, Demetrios; Topsis-Giotis, Iasonas; Agapitos, Antonis; Kesisoglou, Stilianos; Panagiotou, Apostolos; Saoulidou, Niki; Tziaferi, Eirini; Evangelou, Ioannis; Flouris, Giannis; Foudas, Costas; Kokkas, Panagiotis; Loukas, Nikitas; Manthos, Nikolaos; Papadopoulos, Ioannis; Paradas, Evangelos; Filipovic, Nicolas; Bencze, Gyorgy; Hajdu, Csaba; Hidas, Pàl; Horvath, Dezso; Sikler, Ferenc; Veszpremi, Viktor; Vesztergombi, Gyorgy; Zsigmond, Anna Julia; Beni, Noemi; Czellar, Sandor; Karancsi, János; Molnar, Jozsef; Szillasi, Zoltan; Bartók, Márton; Makovec, Alajos; Raics, Peter; Trocsanyi, Zoltan Laszlo; Ujvari, Balazs; Bahinipati, Seema; Choudhury, Somnath; Mal, Prolay; Mandal, Koushik; Nayak, Aruna; Sahoo, Deepak Kumar; Sahoo, Niladribihari; Swain, Sanjay Kumar; Bansal, Sunil; Beri, Suman Bala; Bhatnagar, Vipin; Chawla, Ridhi; Gupta, Ruchi; Bhawandeep, Bhawandeep; Kalsi, Amandeep Kaur; Kaur, Anterpreet; Kaur, Manjit; Kumar, Ramandeep; Mehta, Ankita; Mittal, Monika; Singh, Jasbir; Walia, Genius; Kumar, Ashok; Bhardwaj, Ashutosh; Choudhary, Brajesh C; Garg, Rocky Bala; Keshri, Sumit; Kumar, Ajay; Malhotra, Shivali; Naimuddin, Md; Nishu, Nishu; Ranjan, Kirti; Sharma, Ramkrishna; Sharma, Varun; Bhattacharya, Rajarshi; Bhattacharya, Satyaki; Chatterjee, Kalyanmoy; Dey, Sourav; Dutt, Suneel; Dutta, Suchandra; Ghosh, Shamik; Majumdar, Nayana; Modak, Atanu; Mondal, Kuntal; Mukhopadhyay, Supratik; Nandan, Saswati; Purohit, Arnab; Roy, Ashim; Roy, Debarati; Roy Chowdhury, Suvankar; Sarkar, Subir; Sharan, Manoj; Thakur, Shalini; Behera, Prafulla Kumar; Chudasama, Ruchi; Dutta, Dipanwita; Jha, Vishwajeet; Kumar, Vineet; Mohanty, Ajit Kumar; Netrakanti, Pawan Kumar; Pant, Lalit Mohan; Shukla, Prashant; Topkar, Anita; Aziz, Tariq; Dugad, Shashikant; Kole, Gouranga; Mahakud, Bibhuprasad; Mitra, Soureek; Mohanty, Gagan Bihari; Sur, Nairit; Sutar, Bajrang; Banerjee, Sudeshna; Bhowmik, Sandeep; Dewanjee, Ram Krishna; Ganguly, Sanmay; Guchait, Monoranjan; Jain, Sandhya; Kumar, Sanjeev; Maity, Manas; Majumder, Gobinda; Mazumdar, Kajari; Parida, Bibhuti; Sarkar, Tanmay; Wickramage, Nadeesha; Chauhan, Shubhanshu; Dube, Sourabh; Kapoor, Anshul; Kothekar, Kunal; Rane, Aditee; Sharma, Seema; Bakhshiansohi, Hamed; Behnamian, Hadi; Chenarani, Shirin; Eskandari Tadavani, Esmaeel; Etesami, Seyed Mohsen; Fahim, Ali; Khakzad, Mohsen; Mohammadi Najafabadi, Mojtaba; Naseri, Mohsen; Paktinat Mehdiabadi, Saeid; Rezaei Hosseinabadi, Ferdos; Safarzadeh, Batool; Zeinali, Maryam; Felcini, Marta; Grunewald, Martin; Abbrescia, Marcello; Calabria, Cesare; Caputo, Claudio; Colaleo, Anna; Creanza, Donato; Cristella, Leonardo; De Filippis, Nicola; De Palma, Mauro; Fiore, Luigi; Iaselli, Giuseppe; Maggi, Giorgio; Maggi, Marcello; Miniello, Giorgia; My, Salvatore; Nuzzo, Salvatore; Pompili, Alexis; Pugliese, Gabriella; Radogna, Raffaella; Ranieri, Antonio; Selvaggi, Giovanna; Silvestris, Lucia; Venditti, Rosamaria; Abbiendi, Giovanni; Battilana, Carlo; Bonacorsi, Daniele; Braibant-Giacomelli, Sylvie; Brigliadori, Luca; Campanini, Renato; Capiluppi, Paolo; Castro, Andrea; Cavallo, Francesca Romana; Chhibra, Simranjit Singh; Codispoti, Giuseppe; Cuffiani, Marco; Dallavalle, Gaetano-Marco; Fabbri, Fabrizio; Fanfani, Alessandra; Fasanella, Daniele; Giacomelli, Paolo; Grandi, Claudio; Guiducci, Luigi; Marcellini, Stefano; Masetti, Gianni; Montanari, Alessandro; Navarria, Francesco; Perrotta, Andrea; Rossi, Antonio; Rovelli, Tiziano; Siroli, Gian Piero; Tosi, Nicolò; Albergo, Sebastiano; Chiorboli, Massimiliano; Costa, Salvatore; Di Mattia, Alessandro; Giordano, Ferdinando; Potenza, Renato; Tricomi, Alessia; Tuve, Cristina; Barbagli, Giuseppe; Ciulli, Vitaliano; Civinini, Carlo; D'Alessandro, Raffaello; Focardi, Ettore; Gori, Valentina; Lenzi, Piergiulio; Meschini, Marco; Paoletti, Simone; Sguazzoni, Giacomo; Viliani, Lorenzo; Benussi, Luigi; Bianco, Stefano; Fabbri, Franco; Piccolo, Davide; Primavera, Federica; Calvelli, Valerio; Ferro, Fabrizio; Lo Vetere, Maurizio; Monge, Maria Roberta; Robutti, Enrico; Tosi, Silvano; Brianza, Luca; Dinardo, Mauro Emanuele; Fiorendi, Sara; Gennai, Simone; Ghezzi, Alessio; Govoni, Pietro; Malvezzi, Sandra; Manzoni, Riccardo Andrea; Marzocchi, Badder; Menasce, Dario; Moroni, Luigi; Paganoni, Marco; Pedrini, Daniele; Pigazzini, Simone; Ragazzi, Stefano; Tabarelli de Fatis, Tommaso; Buontempo, Salvatore; Cavallo, Nicola; De Nardo, Guglielmo; Di Guida, Salvatore; Esposito, Marco; Fabozzi, Francesco; Iorio, Alberto Orso Maria; Lanza, Giuseppe; Lista, Luca; Meola, Sabino; Merola, Mario; Paolucci, Pierluigi; Sciacca, Crisostomo; Thyssen, Filip; Azzi, Patrizia; Bacchetta, Nicola; Benato, Lisa; Bisello, Dario; Boletti, Alessio; Carlin, Roberto; Carvalho Antunes De Oliveira, Alexandra; Checchia, Paolo; Dall'Osso, Martino; De Castro Manzano, Pablo; Dorigo, Tommaso; Dosselli, Umberto; Gasparini, Fabrizio; Gasparini, Ugo; Gozzelino, Andrea; Lacaprara, Stefano; Margoni, Martino; Meneguzzo, Anna Teresa; Pazzini, Jacopo; Pozzobon, Nicola; Ronchese, Paolo; Simonetto, Franco; Torassa, Ezio; Tosi, Mia; Zanetti, Marco; Zotto, Pierluigi; Zucchetta, Alberto; Zumerle, Gianni; Braghieri, Alessandro; Magnani, Alice; Montagna, Paolo; Ratti, Sergio P; Re, Valerio; Riccardi, Cristina; Salvini, Paola; Vai, Ilaria; Vitulo, Paolo; Alunni Solestizi, Luisa; Bilei, Gian Mario; Ciangottini, Diego; Fanò, Livio; Lariccia, Paolo; Leonardi, Roberto; Mantovani, Giancarlo; Menichelli, Mauro; Saha, Anirban; Santocchia, Attilio; Androsov, Konstantin; Azzurri, Paolo; Bagliesi, Giuseppe; Bernardini, Jacopo; Boccali, Tommaso; Castaldi, Rino; Ciocci, Maria Agnese; Dell'Orso, Roberto; Donato, Silvio; Fedi, Giacomo; Giassi, Alessandro; Grippo, Maria Teresa; Ligabue, Franco; Lomtadze, Teimuraz; Martini, Luca; Messineo, Alberto; Palla, Fabrizio; Rizzi, Andrea; Savoy-Navarro, Aurore; Spagnolo, Paolo; Tenchini, Roberto; Tonelli, Guido; Venturi, Andrea; Verdini, Piero Giorgio; Barone, Luciano; Cavallari, Francesca; Cipriani, Marco; D'imperio, Giulia; Del Re, Daniele; Diemoz, Marcella; Gelli, Simone; Jorda, Clara; Longo, Egidio; Margaroli, Fabrizio; Meridiani, Paolo; Organtini, Giovanni; Paramatti, Riccardo; Preiato, Federico; Rahatlou, Shahram; Rovelli, Chiara; Santanastasio, Francesco; Amapane, Nicola; Arcidiacono, Roberta; Argiro, Stefano; Arneodo, Michele; Bartosik, Nazar; Bellan, Riccardo; Biino, Cristina; Cartiglia, Nicolo; Costa, Marco; Covarelli, Roberto; Degano, Alessandro; Demaria, Natale; Finco, Linda; Kiani, Bilal; Mariotti, Chiara; Maselli, Silvia; Migliore, Ernesto; Monaco, Vincenzo; Monteil, Ennio; Obertino, Maria Margherita; Pacher, Luca; Pastrone, Nadia; Pelliccioni, Mario; Pinna Angioni, Gian Luca; Ravera, Fabio; Romero, Alessandra; Ruspa, Marta; Sacchi, Roberto; Shchelina, Ksenia; Sola, Valentina; Solano, Ada; Staiano, Amedeo; Traczyk, Piotr; Belforte, Stefano; Candelise, Vieri; Casarsa, Massimo; Cossutti, Fabio; Della Ricca, Giuseppe; La Licata, Chiara; Schizzi, Andrea; Zanetti, Anna; Kim, Dong Hee; Kim, Gui Nyun; Kim, Min Suk; Lee, Sangeun; Lee, Seh Wook; Oh, Young Do; Sekmen, Sezen; Son, Dong-Chul; Yang, Yu Chul; Kim, Hyunsoo; Lee, Ari; Brochero Cifuentes, Javier Andres; Kim, Tae Jeong; Cho, Sungwoong; Choi, Suyong; Go, Yeonju; Gyun, Dooyeon; Ha, Seungkyu; Hong, Byung-Sik; Jo, Youngkwon; Kim, Yongsun; Lee, Byounghoon; Lee, Kisoo; Lee, Kyong Sei; Lee, Songkyo; Lim, Jaehoon; Park, Sung Keun; Roh, Youn; Almond, John; Kim, Junho; Oh, Sung Bin; Seo, Seon-hee; Yang, Unki; Yoo, Hwi Dong; Yu, Geum Bong; Choi, Minkyoo; Kim, Hyunchul; Kim, Hyunyong; Kim, Ji Hyun; Lee, Jason Sang Hun; Park, Inkyu; Ryu, Geonmo; Ryu, Min Sang; Choi, Young-Il; Goh, Junghwan; Kim, Donghyun; Kwon, Eunhyang; Lee, Jongseok; Yu, Intae; Dudenas, Vytautas; Juodagalvis, Andrius; Vaitkus, Juozas; Ahmed, Ijaz; Ibrahim, Zainol Abidin; Komaragiri, Jyothsna Rani; Md Ali, Mohd Adli Bin; Mohamad Idris, Faridah; Wan Abdullah, Wan Ahmad Tajuddin; Yusli, Mohd Nizam; Zolkapli, Zukhaimira; Casimiro Linares, Edgar; Castilla-Valdez, Heriberto; De La Cruz-Burelo, Eduard; Heredia-De La Cruz, Ivan; Hernandez-Almada, Alberto; Lopez-Fernandez, Ricardo; Mejia Guisao, Jhovanny; Sánchez Hernández, Alberto; Carrillo Moreno, Salvador; Vazquez Valencia, Fabiola; Pedraza, Isabel; Salazar Ibarguen, Humberto Antonio; Uribe Estrada, Cecilia; Morelos Pineda, Antonio; Krofcheck, David; Butler, Philip H; Ahmad, Ashfaq; Ahmad, Muhammad; Hassan, Qamar; Hoorani, Hafeez R; Khan, Wajid Ali; Qazi, Shamona; Shoaib, Muhammad; Waqas, Muhammad; Bialkowska, Helena; Bluj, Michal; Boimska, Bożena; Frueboes, Tomasz; Górski, Maciej; Kazana, Malgorzata; Nawrocki, Krzysztof; Romanowska-Rybinska, Katarzyna; Szleper, Michal; Zalewski, Piotr; Bunkowski, Karol; Byszuk, Adrian; Doroba, Krzysztof; Kalinowski, Artur; Konecki, Marcin; Krolikowski, Jan; Misiura, Maciej; Olszewski, Michal; Walczak, Marek; Bargassa, Pedrame; Beirão Da Cruz E Silva, Cristóvão; Di Francesco, Agostino; Faccioli, Pietro; Ferreira Parracho, Pedro Guilherme; Gallinaro, Michele; Hollar, Jonathan; Leonardo, Nuno; Lloret Iglesias, Lara; Nemallapudi, Mythra Varun; Rodrigues Antunes, Joao; Seixas, Joao; Toldaiev, Oleksii; Vadruccio, Daniele; Varela, Joao; Vischia, Pietro; Bunin, Pavel; Gavrilenko, Mikhail; Golutvin, Igor; Gorbounov, Nikolai; Gorbunov, Ilya; Karjavin, Vladimir; Kozlov, Guennady; Lanev, Alexander; Malakhov, Alexander; Matveev, Viktor; Moisenz, Petr; Palichik, Vladimir; Perelygin, Victor; Savina, Maria; Shmatov, Sergey; Shulha, Siarhei; Skatchkov, Nikolai; Smirnov, Vitaly; Zarubin, Anatoli; Chtchipounov, Leonid; Golovtsov, Victor; Ivanov, Yury; Kim, Victor; Kuznetsova, Ekaterina; Murzin, Victor; Oreshkin, Vadim; Sulimov, Valentin; Vorobyev, Alexey; Andreev, Yuri; Dermenev, Alexander; Gninenko, Sergei; Golubev, Nikolai; Karneyeu, Anton; Kirsanov, Mikhail; Krasnikov, Nikolai; Pashenkov, Anatoli; Tlisov, Danila; Toropin, Alexander; Epshteyn, Vladimir; Gavrilov, Vladimir; Lychkovskaya, Natalia; Popov, Vladimir; Pozdnyakov, Ivan; Safronov, Grigory; Spiridonov, Alexander; Toms, Maria; Vlasov, Evgueni; Zhokin, Alexander; Chadeeva, Marina; Danilov, Mikhail; Zhemchugov, Evgenii; Andreev, Vladimir; Azarkin, Maksim; Dremin, Igor; Kirakosyan, Martin; Leonidov, Andrey; Rusakov, Sergey V; Terkulov, Adel; Baskakov, Alexey; Belyaev, Andrey; Boos, Edouard; Dubinin, Mikhail; Dudko, Lev; Ershov, Alexander; Gribushin, Andrey; Klyukhin, Vyacheslav; Kodolova, Olga; Lokhtin, Igor; Miagkov, Igor; Obraztsov, Stepan; Petrushanko, Sergey; Savrin, Viktor; Snigirev, Alexander; Azhgirey, Igor; Bayshev, Igor; Bitioukov, Sergei; Elumakhov, Dmitry; Kachanov, Vassili; Kalinin, Alexey; Konstantinov, Dmitri; Krychkine, Victor; Petrov, Vladimir; Ryutin, Roman; Sobol, Andrei; Troshin, Sergey; Tyurin, Nikolay; Uzunian, Andrey; Volkov, Alexey; Adzic, Petar; Cirkovic, Predrag; Devetak, Damir; Milosevic, Jovan; Rekovic, Vladimir; Alcaraz Maestre, Juan; Calvo, Enrique; Cerrada, Marcos; Chamizo Llatas, Maria; Colino, Nicanor; De La Cruz, Begona; Delgado Peris, Antonio; Escalante Del Valle, Alberto; Fernandez Bedoya, Cristina; Fernández Ramos, Juan Pablo; Flix, Jose; Fouz, Maria Cruz; Garcia-Abia, Pablo; Gonzalez Lopez, Oscar; Goy Lopez, Silvia; Hernandez, Jose M; Josa, Maria Isabel; Navarro De Martino, Eduardo; Pérez-Calero Yzquierdo, Antonio María; Puerta Pelayo, Jesus; Quintario Olmeda, Adrián; Redondo, Ignacio; Romero, Luciano; Senghi Soares, Mara; de Trocóniz, Jorge F; Missiroli, Marino; Moran, Dermot; Cuevas, Javier; Fernandez Menendez, Javier; Gonzalez Caballero, Isidro; Palencia Cortezon, Enrique; Sanchez Cruz, Sergio; Vizan Garcia, Jesus Manuel; Cabrillo, Iban Jose; Calderon, Alicia; Castiñeiras De Saa, Juan Ramon; Curras, Esteban; Fernandez, Marcos; Garcia-Ferrero, Juan; Gomez, Gervasio; Lopez Virto, Amparo; Marco, Jesus; Martinez Rivero, Celso; Matorras, Francisco; Piedra Gomez, Jonatan; Rodrigo, Teresa; Ruiz-Jimeno, Alberto; Scodellaro, Luca; Trevisani, Nicolò; Vila, Ivan; Vilar Cortabitarte, Rocio; Abbaneo, Duccio; Auffray, Etiennette; Auzinger, Georg; Bachtis, Michail; Baillon, Paul; Ball, Austin; Barney, David; Bloch, Philippe; Bocci, Andrea; Bonato, Alessio; Botta, Cristina; Camporesi, Tiziano; Castello, Roberto; Cepeda, Maria; Cerminara, Gianluca; D'Alfonso, Mariarosaria; D'Enterria, David; Dabrowski, Anne; Daponte, Vincenzo; David Tinoco Mendes, Andre; De Gruttola, Michele; De Guio, Federico; De Roeck, Albert; Di Marco, Emanuele; Dobson, Marc; Dordevic, Milos; Dorney, Brian; Du Pree, Tristan; Duggan, Daniel; Dünser, Marc; Dupont, Niels; Elliott-Peisert, Anna; Fartoukh, Stephane; Franzoni, Giovanni; Fulcher, Jonathan; Funk, Wolfgang; Gigi, Dominique; Gill, Karl; Girone, Maria; Glege, Frank; Gundacker, Stefan; Guthoff, Moritz; Hammer, Josef; Harris, Philip; Hegeman, Jeroen; Innocente, Vincenzo; Janot, Patrick; Kirschenmann, Henning; Knünz, Valentin; Kortelainen, Matti J; Kousouris, Konstantinos; Krammer, Manfred; Lecoq, Paul; Lourenco, Carlos; Lucchini, Marco Toliman; Magini, Nicolo; Malgeri, Luca; Mannelli, Marcello; Martelli, Arabella; Meijers, Frans; Mersi, Stefano; Meschi, Emilio; Moortgat, Filip; Morovic, Srecko; Mulders, Martijn; Neugebauer, Hannes; Orfanelli, Styliani; Orsini, Luciano; Pape, Luc; Perez, Emmanuelle; Peruzzi, Marco; Petrilli, Achille; Petrucciani, Giovanni; Pfeiffer, Andreas; Pierini, Maurizio; Racz, Attila; Reis, Thomas; Rolandi, Gigi; Rovere, Marco; Ruan, Manqi; Sakulin, Hannes; Sauvan, Jean-Baptiste; Schäfer, Christoph; Schwick, Christoph; Seidel, Markus; Sharma, Archana; Silva, Pedro; Simon, Michal; Sphicas, Paraskevas; Steggemann, Jan; Stoye, Markus; Takahashi, Yuta; Treille, Daniel; Triossi, Andrea; Tsirou, Andromachi; Veckalns, Viesturs; Veres, Gabor Istvan; Wardle, Nicholas; Zagoździńska, Agnieszka; Zeuner, Wolfram Dietrich; Bertl, Willi; Deiters, Konrad; Erdmann, Wolfram; Horisberger, Roland; Ingram, Quentin; Kaestli, Hans-Christian; Kotlinski, Danek; Langenegger, Urs; Rohe, Tilman; Bachmair, Felix; Bäni, Lukas; Bianchini, Lorenzo; Casal, Bruno; Dissertori, Günther; Dittmar, Michael; Donegà, Mauro; Eller, Philipp; Grab, Christoph; Heidegger, Constantin; Hits, Dmitry; Hoss, Jan; Kasieczka, Gregor; Lecomte, Pierre; Lustermann, Werner; Mangano, Boris; Marionneau, Matthieu; Martinez Ruiz del Arbol, Pablo; Masciovecchio, Mario; Meinhard, Maren Tabea; Meister, Daniel; Micheli, Francesco; Musella, Pasquale; Nessi-Tedaldi, Francesca; Pandolfi, Francesco; Pata, Joosep; Pauss, Felicitas; Perrin, Gaël; Perrozzi, Luca; Quittnat, Milena; Rossini, Marco; Schönenberger, Myriam; Starodumov, Andrei; Takahashi, Maiko; Tavolaro, Vittorio Raoul; Theofilatos, Konstantinos; Wallny, Rainer; Aarrestad, Thea Klaeboe; Amsler, Claude; Caminada, Lea; Canelli, Maria Florencia; Chiochia, Vincenzo; De Cosa, Annapaola; Galloni, Camilla; Hinzmann, Andreas; Hreus, Tomas; Kilminster, Benjamin; Lange, Clemens; Ngadiuba, Jennifer; Pinna, Deborah; Rauco, Giorgia; Robmann, Peter; Salerno, Daniel; Yang, Yong; Doan, Thi Hien; Jain, Shilpi; Khurana, Raman; Konyushikhin, Maxim; Kuo, Chia-Ming; Lin, Willis; Lu, Yun-Ju; Pozdnyakov, Andrey; Yu, Shin-Shan; Kumar, Arun; Chang, Paoti; Chang, You-Hao; Chang, Yu-Wei; Chao, Yuan; Chen, Kai-Feng; Chen, Po-Hsun; Dietz, Charles; Fiori, Francesco; Hou, George Wei-Shu; Hsiung, Yee; Liu, Yueh-Feng; Lu, Rong-Shyang; Miñano Moya, Mercedes; Paganis, Efstathios; Psallidas, Andreas; Tsai, Jui-fa; Tzeng, Yeng-Ming; Asavapibhop, Burin; Singh, Gurpreet; Srimanobhas, Norraphat; Suwonjandee, Narumon; Adiguzel, Aytul; Cerci, Salim; Damarseckin, Serdal; Demiroglu, Zuhal Seyma; Dozen, Candan; Dumanoglu, Isa; Girgis, Semiray; Gokbulut, Gul; Guler, Yalcin; Gurpinar, Emine; Hos, Ilknur; Kangal, Evrim Ersin; Onengut, Gulsen; Ozdemir, Kadri; Sunar Cerci, Deniz; Tali, Bayram; Topakli, Huseyin; Zorbilmez, Caglar; Bilin, Bugra; Bilmis, Selcuk; Isildak, Bora; Karapinar, Guler; Yalvac, Metin; Zeyrek, Mehmet; Gülmez, Erhan; Kaya, Mithat; Kaya, Ozlem; Yetkin, Elif Asli; Yetkin, Taylan; Cakir, Altan; Cankocak, Kerem; Sen, Sercan; Vardarlı, Fuat Ilkehan; Grynyov, Boris; Levchuk, Leonid; Sorokin, Pavel; Aggleton, Robin; Ball, Fionn; Beck, Lana; Brooke, James John; Burns, Douglas; Clement, Emyr; Cussans, David; Flacher, Henning; Goldstein, Joel; Grimes, Mark; Heath, Greg P; Heath, Helen F; Jacob, Jeson; Kreczko, Lukasz; Lucas, Chris; Meng, Zhaoxia; Newbold, Dave M; Paramesvaran, Sudarshan; Poll, Anthony; Sakuma, Tai; Seif El Nasr-storey, Sarah; Senkin, Sergey; Smith, Dominic; Smith, Vincent J; Bell, Ken W; Belyaev, Alexander; Brew, Christopher; Brown, Robert M; Calligaris, Luigi; Cieri, Davide; Cockerill, David JA; Coughlan, John A; Harder, Kristian; Harper, Sam; Olaiya, Emmanuel; Petyt, David; Shepherd-Themistocleous, Claire; Thea, Alessandro; Tomalin, Ian R; Williams, Thomas; Baber, Mark; Bainbridge, Robert; Buchmuller, Oliver; Bundock, Aaron; Burton, Darren; Casasso, Stefano; Citron, Matthew; Colling, David; Corpe, Louie; Dauncey, Paul; Davies, Gavin; De Wit, Adinda; Della Negra, Michel; Dunne, Patrick; Elwood, Adam; Futyan, David; Haddad, Yacine; Hall, Geoffrey; Iles, Gregory; Lane, Rebecca; Laner, Christian; Lucas, Robyn; Lyons, Louis; Magnan, Anne-Marie; Malik, Sarah; Mastrolorenzo, Luca; Nash, Jordan; Nikitenko, Alexander; Pela, Joao; Penning, Bjoern; Pesaresi, Mark; Raymond, David Mark; Richards, Alexander; Rose, Andrew; Seez, Christopher; Tapper, Alexander; Uchida, Kirika; Vazquez Acosta, Monica; Virdee, Tejinder; Zenz, Seth Conrad; Cole, Joanne; Hobson, Peter R; Khan, Akram; Kyberd, Paul; Leslie, Dawn; Reid, Ivan; Symonds, Philip; Teodorescu, Liliana; Turner, Mark; Borzou, Ahmad; Call, Kenneth; Dittmann, Jay; Hatakeyama, Kenichi; Liu, Hongxuan; Pastika, Nathaniel; Charaf, Otman; Cooper, Seth; Henderson, Conor; Rumerio, Paolo; Arcaro, Daniel; Avetisyan, Aram; Bose, Tulika; Gastler, Daniel; Rankin, Dylan; Richardson, Clint; Rohlf, James; Sulak, Lawrence; Zou, David; Benelli, Gabriele; Berry, Edmund; Cutts, David; Ferapontov, Alexey; Garabedian, Alex; Hakala, John; Heintz, Ulrich; Jesus, Orduna; Laird, Edward; Landsberg, Greg; Mao, Zaixing; Narain, Meenakshi; Piperov, Stefan; Sagir, Sinan; Spencer, Eric; Syarif, Rizki; Breedon, Richard; Breto, Guillermo; Burns, Dustin; Calderon De La Barca Sanchez, Manuel; Chauhan, Sushil; Chertok, Maxwell; Conway, John; Conway, Rylan; Cox, Peter Timothy; Erbacher, Robin; Flores, Chad; Funk, Garrett; Gardner, Michael; Ko, Winston; Lander, Richard; Mclean, Christine; Mulhearn, Michael; Pellett, Dave; Pilot, Justin; Ricci-Tam, Francesca; Shalhout, Shalhout; Smith, John; Squires, Michael; Stolp, Dustin; Tripathi, Mani; Wilbur, Scott; Yohay, Rachel; Cousins, Robert; Everaerts, Pieter; Florent, Alice; Hauser, Jay; Ignatenko, Mikhail; Saltzberg, David; Takasugi, Eric; Valuev, Vyacheslav; Weber, Matthias; Burt, Kira; Clare, Robert; Ellison, John Anthony; Gary, J William; Hanson, Gail; Heilman, Jesse; Jandir, Pawandeep; Kennedy, Elizabeth; Lacroix, Florent; Long, Owen Rosser; Malberti, Martina; Olmedo Negrete, Manuel; Paneva, Mirena Ivova; Shrinivas, Amithabh; Wei, Hua; Wimpenny, Stephen; Yates, Brent; Branson, James G; Cerati, Giuseppe Benedetto; Cittolin, Sergio; D'Agnolo, Raffaele Tito; Derdzinski, Mark; Gerosa, Raffaele; Holzner, André; Kelley, Ryan; Klein, Daniel; Letts, James; Macneill, Ian; Olivito, Dominick; Padhi, Sanjay; Pieri, Marco; Sani, Matteo; Sharma, Vivek; Simon, Sean; Tadel, Matevz; Vartak, Adish; Wasserbaech, Steven; Welke, Charles; Wood, John; Würthwein, Frank; Yagil, Avraham; Zevi Della Porta, Giovanni; Bhandari, Rohan; Bradmiller-Feld, John; Campagnari, Claudio; Dishaw, Adam; Dutta, Valentina; Flowers, Kristen; Franco Sevilla, Manuel; Geffert, Paul; George, Christopher; Golf, Frank; Gouskos, Loukas; Gran, Jason; Heller, Ryan; Incandela, Joe; Mccoll, Nickolas; Mullin, Sam Daniel; Ovcharova, Ana; Richman, Jeffrey; Stuart, David; Suarez, Indara; West, Christopher; Yoo, Jaehyeok; Anderson, Dustin; Apresyan, Artur; Bendavid, Joshua; Bornheim, Adolf; Bunn, Julian; Chen, Yi; Duarte, Javier; Mott, Alexander; Newman, Harvey B; Pena, Cristian; Spiropulu, Maria; Vlimant, Jean-Roch; Xie, Si; Zhu, Ren-Yuan; Andrews, Michael Benjamin; Azzolini, Virginia; Calamba, Aristotle; Carlson, Benjamin; Ferguson, Thomas; Paulini, Manfred; Russ, James; Sun, Menglei; Vogel, Helmut; Vorobiev, Igor; Cumalat, John Perry; Ford, William T; Jensen, Frank; Johnson, Andrew; Krohn, Michael; Mulholland, Troy; Stenson, Kevin; Wagner, Stephen Robert; Alexander, James; Chaves, Jorge; Chu, Jennifer; Dittmer, Susan; Mirman, Nathan; Nicolas Kaufman, Gala; Patterson, Juliet Ritchie; Rinkevicius, Aurelijus; Ryd, Anders; Skinnari, Louise; Sun, Werner; Tan, Shao Min; Tao, Zhengcheng; Thom, Julia; Tucker, Jordan; Wittich, Peter; Winn, Dave; Abdullin, Salavat; Albrow, Michael; Apollinari, Giorgio; Banerjee, Sunanda; Bauerdick, Lothar AT; Beretvas, Andrew; Berryhill, Jeffrey; Bhat, Pushpalatha C; Bolla, Gino; Burkett, Kevin; Butler, Joel Nathan; Cheung, Harry; Chlebana, Frank; Cihangir, Selcuk; Cremonesi, Matteo; Elvira, Victor Daniel; Fisk, Ian; Freeman, Jim; Gottschalk, Erik; Gray, Lindsey; Green, Dan; Grünendahl, Stefan; Gutsche, Oliver; Hare, Daryl; Harris, Robert M; Hasegawa, Satoshi; Hirschauer, James; Hu, Zhen; Jayatilaka, Bodhitha; Jindariani, Sergo; Johnson, Marvin; Joshi, Umesh; Klima, Boaz; Kreis, Benjamin; Lammel, Stephan; Linacre, Jacob; Lincoln, Don; Lipton, Ron; Liu, Tiehui; Lopes De Sá, Rafael; Lykken, Joseph; Maeshima, Kaori; Marraffino, John Michael; Maruyama, Sho; Mason, David; McBride, Patricia; Merkel, Petra; Mrenna, Stephen; Nahn, Steve; Newman-Holmes, Catherine; O'Dell, Vivian; Pedro, Kevin; Prokofyev, Oleg; Rakness, Gregory; Ristori, Luciano; Sexton-Kennedy, Elizabeth; Soha, Aron; Spalding, William J; Spiegel, Leonard; Stoynev, Stoyan; Strobbe, Nadja; Taylor, Lucas; Tkaczyk, Slawek; Tran, Nhan Viet; Uplegger, Lorenzo; Vaandering, Eric Wayne; Vernieri, Caterina; Verzocchi, Marco; Vidal, Richard; Wang, Michael; Weber, Hannsjoerg Artur; Whitbeck, Andrew; Acosta, Darin; Avery, Paul; Bortignon, Pierluigi; Bourilkov, Dimitri; Brinkerhoff, Andrew; Carnes, Andrew; Carver, Matthew; Curry, David; Das, Souvik; Field, Richard D; Furic, Ivan-Kresimir; Konigsberg, Jacobo; Korytov, Andrey; Ma, Peisen; Matchev, Konstantin; Mei, Hualin; Milenovic, Predrag; Mitselmakher, Guenakh; Rank, Douglas; Shchutska, Lesya; Sperka, David; Thomas, Laurent; Wang, Jian; Wang, Sean-Jiun; Yelton, John; Linn, Stephan; Markowitz, Pete; Martinez, German; Rodriguez, Jorge Luis; Ackert, Andrew; Adams, Jordon Rowe; Adams, Todd; Askew, Andrew; Bein, Samuel; Diamond, Brendan; Hagopian, Sharon; Hagopian, Vasken; Johnson, Kurtis F; Khatiwada, Ajeeta; Prosper, Harrison; Santra, Arka; Weinberg, Marc; Baarmand, Marc M; Bhopatkar, Vallary; Colafranceschi, Stefano; Hohlmann, Marcus; Kalakhety, Himali; Noonan, Daniel; Roy, Titas; Yumiceva, Francisco; Adams, Mark Raymond; Apanasevich, Leonard; Berry, Douglas; Betts, Russell Richard; Bucinskaite, Inga; Cavanaugh, Richard; Evdokimov, Olga; Gauthier, Lucie; Gerber, Cecilia Elena; Hofman, David Jonathan; Kurt, Pelin; O'Brien, Christine; Sandoval Gonzalez, Irving Daniel; Turner, Paul; Varelas, Nikos; Wu, Zhenbin; Zakaria, Mohammed; Zhang, Jingyu; Bilki, Burak; Clarida, Warren; Dilsiz, Kamuran; Durgut, Süleyman; Gandrajula, Reddy Pratap; Haytmyradov, Maksat; Khristenko, Viktor; Merlo, Jean-Pierre; Mermerkaya, Hamit; Mestvirishvili, Alexi; Moeller, Anthony; Nachtman, Jane; Ogul, Hasan; Onel, Yasar; Ozok, Ferhat; Penzo, Aldo; Snyder, Christina; Tiras, Emrah; Wetzel, James; Yi, Kai; Anderson, Ian; Blumenfeld, Barry; Cocoros, Alice; Eminizer, Nicholas; Fehling, David; Feng, Lei; Gritsan, Andrei; Maksimovic, Petar; Osherson, Marc; Roskes, Jeffrey; Sarica, Ulascan; Swartz, Morris; Xiao, Meng; Xin, Yongjie; You, Can; Al-bataineh, Ayman; Baringer, Philip; Bean, Alice; Bowen, James; Bruner, Christopher; Castle, James; Kenny III, Raymond Patrick; Kropivnitskaya, Anna; Majumder, Devdatta; Mcbrayer, William; Murray, Michael; Sanders, Stephen; Stringer, Robert; Tapia Takaki, Daniel; Wang, Quan; Ivanov, Andrew; Kaadze, Ketino; Khalil, Sadia; Makouski, Mikhail; Maravin, Yurii; Mohammadi, Abdollah; Saini, Lovedeep Kaur; Skhirtladze, Nikoloz; Toda, Sachiko; Lange, David; Rebassoo, Finn; Wright, Douglas; Anelli, Christopher; Baden, Drew; Baron, Owen; Belloni, Alberto; Calvert, Brian; Eno, Sarah Catherine; Ferraioli, Charles; Gomez, Jaime; Hadley, Nicholas John; Jabeen, Shabnam; Kellogg, Richard G; Kolberg, Ted; Kunkle, Joshua; Lu, Ying; Mignerey, Alice; Shin, Young Ho; Skuja, Andris; Tonjes, Marguerite; Tonwar, Suresh C; Apyan, Aram; Barbieri, Richard; Baty, Austin; Bi, Ran; Bierwagen, Katharina; Brandt, Stephanie; Busza, Wit; Cali, Ivan Amos; Demiragli, Zeynep; Di Matteo, Leonardo; Gomez Ceballos, Guillelmo; Goncharov, Maxim; Gulhan, Doga; Hsu, Dylan; Iiyama, Yutaro; Innocenti, Gian Michele; Klute, Markus; Kovalskyi, Dmytro; Krajczar, Krisztian; Lai, Yue Shi; Lee, Yen-Jie; Levin, Andrew; Luckey, Paul David; Marini, Andrea Carlo; Mcginn, Christopher; Mironov, Camelia; Narayanan, Siddharth; Niu, Xinmei; Paus, Christoph; Roland, Christof; Roland, Gunther; Salfeld-Nebgen, Jakob; Stephans, George; Sumorok, Konstanty; Tatar, Kaya; Varma, Mukund; Velicanu, Dragos; Veverka, Jan; Wang, Jing; Wang, Ta-Wei; Wyslouch, Bolek; Yang, Mingming; Zhukova, Victoria; Benvenuti, Alberto; Chatterjee, Rajdeep Mohan; Dahmes, Bryan; Evans, Andrew; Finkel, Alexey; Gude, Alexander; Hansen, Peter; Kalafut, Sean; Kao, Shih-Chuan; Klapoetke, Kevin; Kubota, Yuichi; Lesko, Zachary; Mans, Jeremy; Nourbakhsh, Shervin; Ruckstuhl, Nicole; Rusack, Roger; Tambe, Norbert; Turkewitz, Jared; Acosta, John Gabriel; Oliveros, Sandra; Avdeeva, Ekaterina; Bartek, Rachel; Bloom, Kenneth; Bose, Suvadeep; Claes, Daniel R; Dominguez, Aaron; Fangmeier, Caleb; Gonzalez Suarez, Rebeca; Kamalieddin, Rami; Knowlton, Dan; Kravchenko, Ilya; Meier, Frank; Monroy, Jose; Siado, Joaquin Emilo; Snow, Gregory R; Stieger, Benjamin; Alyari, Maral; Dolen, James; George, Jimin; Godshalk, Andrew; Harrington, Charles; Iashvili, Ia; Kaisen, Josh; Kharchilava, Avto; Kumar, Ashish; Parker, Ashley; Rappoccio, Salvatore; Roozbahani, Bahareh; Alverson, George; Barberis, Emanuela; Baumgartel, Darin; Chasco, Matthew; Hortiangtham, Apichart; Massironi, Andrea; Morse, David Michael; Nash, David; Orimoto, Toyoko; Teixeira De Lima, Rafael; Trocino, Daniele; Wang, Ren-Jie; Wood, Darien; Bhattacharya, Saptaparna; Hahn, Kristan Allan; Kubik, Andrew; Low, Jia Fu; Mucia, Nicholas; Odell, Nathaniel; Pollack, Brian; Schmitt, Michael Henry; Sung, Kevin; Trovato, Marco; Velasco, Mayda; Dev, Nabarun; Hildreth, Michael; Hurtado Anampa, Kenyi; Jessop, Colin; Karmgard, Daniel John; Kellams, Nathan; Lannon, Kevin; Marinelli, Nancy; Meng, Fanbo; Mueller, Charles; Musienko, Yuri; Planer, Michael; Reinsvold, Allison; Ruchti, Randy; Rupprecht, Nathaniel; Smith, Geoffrey; Taroni, Silvia; Valls, Nil; Wayne, Mitchell; Wolf, Matthias; Woodard, Anna; Alimena, Juliette; Antonelli, Louis; Brinson, Jessica; Bylsma, Ben; Durkin, Lloyd Stanley; Flowers, Sean; Francis, Brian; Hart, Andrew; Hill, Christopher; Hughes, Richard; Ji, Weifeng; Liu, Bingxuan; Luo, Wuming; Puigh, Darren; Rodenburg, Marissa; Winer, Brian L; Wulsin, Howard Wells; Cooperstein, Stephane; Driga, Olga; Elmer, Peter; Hardenbrook, Joshua; Hebda, Philip; Luo, Jingyu; Marlow, Daniel; Medvedeva, Tatiana; Mooney, Michael; Olsen, James; Palmer, Christopher; Piroué, Pierre; Stickland, David; Tully, Christopher; Zuranski, Andrzej; Malik, Sudhir; Barker, Anthony; Barnes, Virgil E; Benedetti, Daniele; Folgueras, Santiago; Gutay, Laszlo; Jha, Manoj; Jones, Matthew; Jung, Andreas Werner; Jung, Kurt; Miller, David Harry; Neumeister, Norbert; Radburn-Smith, Benjamin Charles; Shi, Xin; Sun, Jian; Svyatkovskiy, Alexey; Wang, Fuqiang; Xie, Wei; Xu, Lingshan; Parashar, Neeti; Stupak, John; Adair, Antony; Akgun, Bora; Chen, Zhenyu; Ecklund, Karl Matthew; Geurts, Frank JM; Guilbaud, Maxime; Li, Wei; Michlin, Benjamin; Northup, Michael; Padley, Brian Paul; Redjimi, Radia; Roberts, Jay; Rorie, Jamal; Tu, Zhoudunming; Zabel, James; Betchart, Burton; Bodek, Arie; de Barbaro, Pawel; Demina, Regina; Duh, Yi-ting; Ferbel, Thomas; Galanti, Mario; Garcia-Bellido, Aran; Han, Jiyeon; Hindrichs, Otto; Khukhunaishvili, Aleko; Lo, Kin Ho; Tan, Ping; Verzetti, Mauro; Chou, John Paul; Contreras-Campana, Emmanuel; Gershtein, Yuri; Gómez Espinosa, Tirso Alejandro; Halkiadakis, Eva; Heindl, Maximilian; Hidas, Dean; Hughes, Elliot; Kaplan, Steven; Kunnawalkam Elayavalli, Raghav; Kyriacou, Savvas; Lath, Amitabh; Nash, Kevin; Saka, Halil; Salur, Sevil; Schnetzer, Steve; Sheffield, David; Somalwar, Sunil; Stone, Robert; Thomas, Scott; Thomassen, Peter; Walker, Matthew; Foerster, Mark; Heideman, Joseph; Riley, Grant; Rose, Keith; Spanier, Stefan; Thapa, Krishna; Bouhali, Othmane; Castaneda Hernandez, Alfredo; Celik, Ali; Dalchenko, Mykhailo; De Mattia, Marco; Delgado, Andrea; Dildick, Sven; Eusebi, Ricardo; Gilmore, Jason; Huang, Tao; Juska, Evaldas; Kamon, Teruki; Krutelyov, Vyacheslav; Mueller, Ryan; Pakhotin, Yuriy; Patel, Rishi; Perloff, Alexx; Perniè, Luca; Rathjens, Denis; Rose, Anthony; Safonov, Alexei; Tatarinov, Aysen; Ulmer, Keith; Akchurin, Nural; Cowden, Christopher; Damgov, Jordan; Dragoiu, Cosmin; Dudero, Phillip Russell; Faulkner, James; Kunori, Shuichi; Lamichhane, Kamal; Lee, Sung Won; Libeiro, Terence; Undleeb, Sonaina; Volobouev, Igor; Wang, Zhixing; Delannoy, Andrés G; Greene, Senta; Gurrola, Alfredo; Janjam, Ravi; Johns, Willard; Maguire, Charles; Melo, Andrew; Ni, Hong; Sheldon, Paul; Tuo, Shengquan; Velkovska, Julia; Xu, Qiao; Arenton, Michael Wayne; Barria, Patrizia; Cox, Bradley; Goodell, Joseph; Hirosky, Robert; Ledovskoy, Alexander; Li, Hengne; Neu, Christopher; Sinthuprasith, Tutanon; Sun, Xin; Wang, Yanchu; Wolfe, Evan; Xia, Fan; Clarke, Christopher; Harr, Robert; Karchin, Paul Edmund; Lamichhane, Pramod; Sturdy, Jared; Belknap, Donald; Dasu, Sridhara; Dodd, Laura; Duric, Senka; Gomber, Bhawna; Grothe, Monika; Herndon, Matthew; Hervé, Alain; Klabbers, Pamela; Lanaro, Armando; Levine, Aaron; Long, Kenneth; Loveless, Richard; Ojalvo, Isabel; Perry, Thomas; Pierro, Giuseppe Antonio; Polese, Giovanni; Ruggles, Tyler; Savin, Alexander; Sharma, Archana; Smith, Nicholas; Smith, Wesley H; Taylor, Devin; Verwilligen, Piet; Woods, Nathaniel

    2016-07-14

    A search for narrow resonances decaying into dijet final states is performed on data from proton-proton collisions at a center-of-mass energy of 8 TeV, corresponding to an integrated luminosity of 18.8 fb$^{-1}$. The data were collected with the CMS detector using a novel technique called data scouting, in which the information associated with these selected events is much reduced, permitting collection of larger data samples. This technique enables CMS to record events containing jets at a rate of 1 kHz, by collecting the data from the high-level-trigger system. In this way, the sensitivity to low-mass resonances is increased significantly, allowing previously inaccessible couplings of new resonances to quarks and gluons to be probed. The resulting dijet mass distribution yields no evidence of narrow resonances. Upper limits are presented on the resonance cross sections as a function of mass, and compared with a variety of models predicting narrow resonances. The limits are translated into upper limits on th...

  9. Lead concentration in roadside soils and vegetation in Damascus city

    International Nuclear Information System (INIS)

    Othman, I.; Al-Oudat, M.; Al-Masri, M.S.

    1998-01-01

    Seasonal variations of lead concentration in roadside soils and plants in 12 sites in Damascus city have been investigated. Lead concentrations in soil were found to be varied from 78.4 ppm to 832 ppm; lower levels in the wet period than in the dry period were observed. While lead levels in roadside plants varied between 3.39 ppm to 13.28 ppm. The results have also shown that most of the vegetables grown on the roadside of Damascus city have high concentrations of lead and the normal washing does not decrease it to unacceptable level. (author)

  10. Distribution of lead in teeth

    Energy Technology Data Exchange (ETDEWEB)

    Fremlin, J H; Tanti-Wipawin, W [Birmingham Univ. (UK). Dept. of Physics

    1976-07-01

    There is currently much concern with the amount of lead in the environment. Measurement of lead in teeth is being used to give information on the integrated uptake of lead by the individual over a period. The distribution of lead within individual teeth, is examined with the object of distinguishing lead deposited during formation or calcification from that taken up by the tooth over its working life after eruption. A tooth is sectioned and bombarded with 30-MeV ions of helium-3 from the Birmingham 1.52-m cyclotron, which produces polonium isotopes. The main useful activity is due to polonium-206, an ..cap alpha.. emitter, half-life 8 d. These ..cap alpha.. particles can be recorded by a plastic solid-state track detector.

  11. Distribution of lead in teeth

    International Nuclear Information System (INIS)

    Fremlin, J.H.; Tanti-Wipawin, W.

    1976-01-01

    There is currently much concern with the amount of lead in the environment. Measurement of lead in teeth is being used to give information on the integrated uptake of lead by the individual over a period. The distribution of lead within individual teeth, is examined with the object of distinguishing lead deposited during formation or calcification from that taken up by the tooth over its working life after eruption. A tooth is sectioned and bombarded with 30-MeV ions of helium-3 from the Birmingham 1.52-m cyclotron, which produces polonium isotopes. The main useful activity is due to polonium-206, an α emitter, half-life 8 d. These α particles can be recorded by a plastic solid-state track detector. (U.K.)

  12. Periodicity in Age-Resolved Populations

    Science.gov (United States)

    Esipov, Sergei

    We discuss the interplay between the non-linear diffusion and age-resolved population dynamics. Depending on the age properties of collective migration the system may exhibit continuous joint expansion of all ages or continuous expansion with age segregation. Between these two obvious limiting regimes there is an interesting window of periodic expansion, which has been previously used by us in modeling bacterial colonies of Proteus mirabilis. In order to test whether the age-dependent collective migration leads to periodicity in other systems we performed a Fourier analysis of historical data on ethnic expansions and found multiple co-existing periods of activity.

  13. Time-resolved diode dosimetry calibration through Monte Carlo modeling for in vivo passive scattered proton therapy range verification.

    Science.gov (United States)

    Toltz, Allison; Hoesl, Michaela; Schuemann, Jan; Seuntjens, Jan; Lu, Hsiao-Ming; Paganetti, Harald

    2017-11-01

    Our group previously introduced an in vivo proton range verification methodology in which a silicon diode array system is used to correlate the dose rate profile per range modulation wheel cycle of the detector signal to the water-equivalent path length (WEPL) for passively scattered proton beam delivery. The implementation of this system requires a set of calibration data to establish a beam-specific response to WEPL fit for the selected 'scout' beam (a 1 cm overshoot of the predicted detector depth with a dose of 4 cGy) in water-equivalent plastic. This necessitates a separate set of measurements for every 'scout' beam that may be appropriate to the clinical case. The current study demonstrates the use of Monte Carlo simulations for calibration of the time-resolved diode dosimetry technique. Measurements for three 'scout' beams were compared against simulated detector response with Monte Carlo methods using the Tool for Particle Simulation (TOPAS). The 'scout' beams were then applied in the simulation environment to simulated water-equivalent plastic, a CT of water-equivalent plastic, and a patient CT data set to assess uncertainty. Simulated detector response in water-equivalent plastic was validated against measurements for 'scout' spread out Bragg peaks of range 10 cm, 15 cm, and 21 cm (168 MeV, 177 MeV, and 210 MeV) to within 3.4 mm for all beams, and to within 1 mm in the region where the detector is expected to lie. Feasibility has been shown for performing the calibration of the detector response for three 'scout' beams through simulation for the time-resolved diode dosimetry technique in passive scattered proton delivery. © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

  14. Short- and Long-Term Lead Release after Partial Lead Service Line Replacements in a Metropolitan Water Distribution System.

    Science.gov (United States)

    Deshommes, Elise; Laroche, Laurent; Deveau, Dominique; Nour, Shokoufeh; Prévost, Michèle

    2017-09-05

    Thirty-three households were monitored in a full-scale water distribution system, to investigate the impact of recent (sampling over a period of 1-20 months. Point-of-entry filters were installed to capture sporadic release of particulate lead from the lead service lines (LSLs). Mean concentrations increased immediately after PLSLRs and erratic particulate lead spikes were observed over the 18 month post-PLSLR monitoring period. The mass of lead released during this time frame indicates the occurrence of galvanic corrosion and scale destabilization. System-wide, lead concentrations were however lower in households with PLSLRs as compared to those with no replacement, especially for old PLSLRs. Nonetheless, 61% of PLSLR samples still exceeded 10 μg/L, reflecting the importance of implementing full LSL replacement and efficient risk communication. Acute concentrations measured immediately after PLSLRs demonstrate the need for appropriate flushing procedures to prevent lead poisoning.

  15. "Scoutismo mirando al sur": el origen del movimiento scout a escala comparada. Argentina y Brasil en las primeras décadas del siglo XX

    Directory of Open Access Journals (Sweden)

    Maria Augusta Martiarena de Oliveira

    2015-10-01

    Full Text Available Desde su origen en la primera década del siglo XX hasta los tiempos actuales, el scoutismo ha sido y es el mayor movimiento de infantes y jóvenes asociado a las actividades de tiempo libre del mundo. Aproximadamente setenta millones de muchachos y hombres y cuarenta millones de niñas y mujeres han sido o son miembros de los dos movimientos fundados por Baden Powell, los scouts y las guías. Actualmente cerca de nueve millones de boy scouts activos y seis millones de niñas y jóvenes se instruyen en la filosofía scout y sus prácticas en alrededor de cien países. El propósito central de esta ponencia es  historiar –desde una perspectiva comparada- el surgimiento del scoutismo en dos países latinoamericanos, Brasil y Argentina, teniendo en cuenta cómo un movimiento internacional es resignificado en los Estados nacionales para construir nacionalidad y formar ciudadanos. La ponencia se dedica, en especial, al análisis de la utilización del scoutismo en las regiones sur de ambos los países. La perspectiva de la historia comparada que se propone intenta, –como ya lo había propuesto Marc Bloch a comienzos de los años 1960[i]-,analizar con procedimientos metodológicos específicos la unidad de un problema en dos sociedades, en este caso en la argentina y la brasilera, sin establecer un orden jerárquico o modélico de una sobre otra. Es pretensión de esta práctica historiográfica liberarse del eurocentrismo, las genarlizaciones y la naturalización del Estado-nación como espacio esencial de la historia, en la intención de aportar explicaciones causales, identificando singularidades y pautas comunes en los procesos históricos. El horizonte temporal seleccionado obedece a que, si bien el inicio del "Estado" argentino es previo, es recién a fines del siglo XIX cuando se profundiza su proceso de consolidación, periodo que coincide con la república brasilera y el surgimiento del scoutismo, concebido como una escuela moral de la

  16. Thoracic pathologies on scout views and bolus tracking slices for computed tomographic cerebral angiography

    Energy Technology Data Exchange (ETDEWEB)

    Groth, M.; Fiehler, J.; Buhk, J.H. [University Medical Center Hamburg-Eppendorf (Germany). Dept. of Diagnostic and Interventional Neuroradiology; Henes, F.O. [University Medical Center Hamburg-Eppendorf (Germany). Dept. of Diagnostic and Interventional Radiology

    2015-08-15

    To evaluate the incidence of additional thoracic pathologic findings (TPF) detected on scout views and corresponding bolus tracking slices (SVBT) for computed tomographic cerebral angiography (CTCA) and to test the reliability and accuracy of these findings. The study collective included 505 consecutive patients who underwent multidetector CTCA. Appendant SVBT of all patients were reviewed for any pathologic findings and patient medical reports were analyzed, if any medical treatment was initiated for the detected pathologic findings. In 18 patients thoracic CT scans were performed in the same session. These were additionally reviewed by two blinded observers to test for intra- and interobserver reliability as well as for accuracy of detecting thoracic pathologies on SVBT. TPF were detected in 165 (33 %) SVBT. The five most common pathologic findings were: pleural effusion, 12 %; pneumonia, 8 %; atelectasis/dystelecatsis, 6 %; pericardial effusion, 2 % and elevated diaphragm, 1 %. For 48 % of these findings medical treatment was initiated. SVBT showed a sensitivity of 53 %, a specificity of 99 %, a positive predictive value of 89 %, a negative predictive value of 94 % and accuracy of 94 % for the detection of TPF. The intraobserver reliability was very good and the interobserver reliability showed moderate agreement. SVBT for CTCA should be reviewed with care by radiologists, since additional TPF can affect patient management. Nevertheless, despite a high specificity of SVBT for detecting TPF, an only moderate sensitivity has to be taken into account.

  17. Age-ordered shirt numbering reduces the selection bias associated with the relative age effect.

    Science.gov (United States)

    Mann, David L; van Ginneken, Pleun J M A

    2017-04-01

    When placed into age groups for junior sporting competition, the relative differences in age between children leads to a bias in who is evaluated as being talented. While the impact of this relative age effect (RAE) is clear, until now there has been no evidence to show how to reduce it. The aim of this study was to determine whether the selection bias associated with the RAE could be reduced. Talent scouts from an elite football club watched junior games and ranked players on the basis of their potential. Scouts were allocated to one of three groups provided with contrasting information about the age of the players: (1) no age information, (2) players' birthdates or (3) knowledge that the numbers on the playing shirts corresponded to the relative age of the players. Results revealed a significant selection bias for the scouts in the no-age information group, and that bias remained when scouts knew the players' dates-of-birth. Strikingly though, the selection bias was eliminated when scouts watched the games knowing the shirt numbers corresponded to the relative ages of the players. The selection bias associated with the RAE can be reduced if information about age is presented appropriately.

  18. Lead dust in Broken Hill homes: effect of remediation on indoor lead levels.

    Science.gov (United States)

    Boreland, F; Lyle, D M

    2006-02-01

    This study was undertaken to determine whether home remediation effectively reduced indoor lead levels in Broken Hill, a long-established silver-lead-zinc mining town in outback Australia. A before-after study of the effect of home remediation on indoor lead levels was embedded into a randomized controlled trial of the effectiveness of remediation for reducing elevated blood lead levels in young children. Moist towelettes were used to measure lead loading (microg/m2) on internal windowsills and internal and entry floors of 98 homes; samples were collected before, immediately after, and 2, 4, 6, 8, and 10 months after remediation. Data were log(10) transformed for the analysis. Remediation reduced average indoor lead levels by approximately 50%, and lead levels remained low for the duration of the follow-up period (10 months). The greatest gains were made in homes with the highest initial lead levels; homes with low preremediation lead levels showed little or no benefit. Before remediation, homes located in areas with high soil lead levels or with "poor" dust proofing had higher lead levels than those in areas with lower soil lead levels or with "medium" or "good" dust proofing; these relative differences remained after remediation. There was no evidence that lead loading was reduced by an increased opportunity to become aware of lead issues. We conclude that remediation is an effective strategy for reducing the lead exposure of children living in homes with high indoor lead levels.

  19. Lead levels in roadside soils and vegetation of Damascus city

    International Nuclear Information System (INIS)

    Othman, I.; Al-Oudat, M.; Al-Masri, M.S.

    1999-01-01

    Seasonal variations of lead concentration in roadside soils and plants in 12 sites in Damascus city have been investigated. Lead concentrations in soil were found to be varied from 78.4 ppm to 832 ppm; lower levels in the wet period than in the dry period were observed. While lead levels in roadside plants varied between 3.39 ppm to 13.28 ppm. The results have also shown that most of the vegetables grown on the roadside of Damascus city have high concentrations of lead and the normal washing does not decrease it to An acceptable level. (author)

  20. Moving without a purpose: an experimental study of swarm guidance in the Western honey bee, Apis mellifera.

    Science.gov (United States)

    Makinson, James C; Beekman, Madeleine

    2014-06-01

    During reproductive swarming, honey bee scouts perform two very important functions. Firstly, they find new nesting locations and return to the swarm cluster to communicate their discoveries. Secondly, once the swarm is ready to depart, informed scout bees act as guides, leading the swarm to its final destination. We have previously hypothesised that the two processes, selecting a new nest site and swarm guidance, are tightly linked in honey bees. When swarms can be laissez faire about where they nest, reaching directional consensus prior to lift off seems unnecessary. If, in contrast, it is essential that the swarm reaches a precise location, either directional consensus must be near unanimous prior to swarm departure or only a select subgroup of the scouts guide the swarm. Here, we tested experimentally whether directional consensus is necessary for the successful guidance of swarms of the Western honey bee Apis mellifera by forcing swarms into the air prior to the completion of the decision-making process. Our results show that swarms were unable to guide themselves prior to the swarm reaching the pre-flight buzzing phase of the decision-making process, even when directional consensus was high. We therefore suggest that not all scouts involved in the decision-making process attempt to guide the swarm. © 2014. Published by The Company of Biologists Ltd.

  1. Iraqi architecture in mogul period

    Directory of Open Access Journals (Sweden)

    Hasan Shatha

    2018-01-01

    Full Text Available Iraqi architecture have many periods passed through it until now, each on from these periods have it is architectural style, also through time these styles interacted among us, to creating kind of space forming, space relationships, and architectural elements (detailed treatments, the research problem being from the multi interacted architectural styles causing some of confused of general characteristic to every style, that we could distinguish by it. Research tries to study architecture style through Mogul Conquest to Baghdad. Aim of research follow main characteristic for this architectural style in the Mogul periods on the level of form, elements, and treatments. Research depending on descriptive and analytical all buildings belong to this period, so from analyzing there style by, general form for building, architectural elements, and it architectural treatment, therefore; repeating this procedures to every building we get some similarities, from these similarities we can making conclusion about pure characteristic of the style of these period. Other side, we also discover some Dissimilar in the building periods, these will lead research to make what interacting among styles in this period, after all that we can drew clearly main characteristic of Architectural Style for Mogul Conquest in Baghdad

  2. Determination of lead levels in roadside soil and plants in Damascus city

    International Nuclear Information System (INIS)

    Othman, I; Al-Oudat, M.; Al-Masri, M.S.

    1997-04-01

    Seasonal variations of lead concentration in roadside soils and plants in 12 sites in Damascus city have been investigated. Lead concentrations in soil were found to be varied from 78.4 ppm to 832 ppm; lower levels in the wet period than in the dry period were observed. While lead levels in roadside plants varied between 3.39 ppm to 13.28 ppm. The results have also shown that most of the vegetables grown on the roadside of Damascus city have high concentrations of lead and the normal washing does not decrease it to unacceptable level. (author). 15 refs., 9 tabs

  3. Epidemiology and Outcomes of Lisfranc Injuries Identified at the National Football League Scouting Combine.

    Science.gov (United States)

    McHale, Kevin J; Vopat, Bryan G; Beaulieu-Jones, Brendin R; Sanchez, George; Whalen, James M; McDonald, Lucas S; DiGiovanni, Christopher W; Theodore, George H; Provencher, Matthew T

    2017-07-01

    Lisfranc injuries are challenging to treat and may have a detrimental effect on athletic performance. (1) Determine the epidemiological characteristics of Lisfranc injuries at the annual National Football League (NFL) Scouting Combine, (2) define player positions at risk for these injuries, and (3) evaluate the impact that these injuries and radiographic findings have on NFL draft position and performance. Cohort study; Level of evidence, 3. All players who sustained a Lisfranc injury prior to Combine evaluation between 2009 and 2015 were evaluated. The epidemiological characteristics, player positions affected, treatment methods, and number of missed collegiate games were recorded. Radiographic outcomes were analyzed via Combine radiograph findings, while NFL performance outcomes were assessed for all Lisfranc injuries (2009-2013) compared with matched controls in the first 2 years of play. A total of 41 of 2162 (1.8%) Combine participants were identified with Lisfranc injuries, of whom 26 of 41 (63.4%) were managed operatively. Players who underwent surgery were more likely to go undrafted compared with players managed nonoperatively (38.5% vs 13.3%, operative vs nonoperative management, respectively; P = .04) and featured a worse NFL draft pick position (155.6 vs 109; P = .03). Lisfranc-injured players when compared with controls were noted to have worse outcomes in terms of NFL draft position (142 vs 111.3, Lisfranc-injured players vs controls, respectively; P = .04), NFL career length 2 years or longer (62.5% vs 69.6%; P = .23), and number of games played (16.9 vs 23.3; P = .001) and started (6.8 vs 10.5; P = .08) within the first 2 years of their NFL career. Radiographs demonstrated that 17 of 41 (41.5%) athletes had residual Lisfranc joint displacement greater than 2 mm compared with the contralateral foot. Lisfranc-injured athletes with greater than 2 mm residual displacement, when compared with matched controls, had worse draft position (156.9 vs 111.2 for

  4. Confusion in the Periodic Table of the Elements.

    Science.gov (United States)

    Fernelius, W. C.; Powell, W. H.

    1982-01-01

    Discusses long (expanded), short (condensed), and pyramidal periodic table formats and documents events leading to a periodic table in which subgroups (families) are designated with the letters A and B, suggesting that this format is confusing for those consulting the table. (JN)

  5. Transition of cord blood lead level, 1985-2002, in the Taipei area and its determinants after the cease of leaded gasoline use

    International Nuclear Information System (INIS)

    Hwang, Y.-H.; Ko Yi; Chiang, C.-D.; Hsu, S.-P.; Lee, Y.-H.; Yu, C.-H.; Chiou, C.-H.; Wang, J.-D.; Chuang, H.-Y.

    2004-01-01

    Lead has long been of concern for its toxicity, impairment of neurobehavioral and cognitive development, and electrophysiological deficits in children, even at levels less than 10 μg/dL. The present study was conducted to elucidate the extent of cord blood lead level decline in the Taipei area from 1985 to 2002 and to explore the factors affecting the cord blood lead level after the cease of leaded gasoline use. In the current study period of 2001-2002, 184 of 1310 newborns delivered in the Taipei Municipal Women and Children Hospital between September 2001 and August 2002 were eligible and randomly selected to participate in this study. Neither of their parents had an occupational lead exposure history. At each delivery, a sample of 5-10 mL umbilical cord blood was collected for lead determination by graphite furnace atomic absorption spectrometry. The cord blood lead level of the newborns in the current study period averaged 2.35±1.12 μg/dL. Together with the cord blood lead averages of 7.48±2.25 and 3.28±1.52 μg/dL obtained from two previous surveys conducted in 1985-1987 and 1990-1992, respectively, the cord blood lead level was significantly decreased (P<0.005). It is estimated that such a reduction in cord blood lead from 7.48 to 2.35 μg/dL for each year's cohort of 260,000 newborns in Taiwan might benefit the economics, ranging from US$8.9 billion to US$12.1 billion by improving the worker productivity. For the time period from 1985 to 2002, there were consistent transition patterns among the yearly fluctuations of air lead level, leaded gasoline consumption, lead content in gasoline, estimated lead amount emitted from the consumed leaded gasoline, and average cord blood lead levels of the three respective study periods. Additionally, every 0.1-g/L reduction in lead content in gasoline might lead to a lowering of cord blood lead level by 1.78 μg/dL. Furthermore, at low level of around 2 μg/dL, a multiple regression analysis demonstrated that

  6. Lead in soils, plants and animals

    Energy Technology Data Exchange (ETDEWEB)

    Scheltinga, H

    1955-01-01

    The toxicity of lead for plants is small, except in the case of water cultures. Animals can absorb more lead without toxic effect than was previously expected. This applies to acute poisoning as well as chronic poisoning. As a result of experiments over many years (Allcroft and Blaxter, 1950) the possibility of chronic lead poisoning has been found to be minute. Rations containing 240 mg lead/kg dried fodder, given daily over a period of three years, did not cause any poisoning at all in cattle thus fed. Where lead poisoning did take place, it was observed that the ratio of lead in the dried fodder was > 1000 mg/kg; the proportion was generally much higher. In normal cases grass contains only 5 to 15 mg lead/kg. The total lead content of samples from arable land was 10 to 25 mg/kg soil. For grassland on peat or clay the amount was slightly higher. The influence on the lead status of soils and plants of fertilizing with compost or copper slag flour, both containing a small percentage of lead, proved to be negligible. It is definite that in normal use, these fertilizers cannot cause any danger for either plant or animal. 24 references, 3 tables.

  7. Nonparametric Inference for Periodic Sequences

    KAUST Repository

    Sun, Ying; Hart, Jeffrey D.; Genton, Marc G.

    2012-01-01

    the periodogram, a widely used tool for period estimation. The CV method is computationally simple and implicitly penalizes multiples of the smallest period, leading to a "virtually" consistent estimator of integer periods. This estimator is investigated both

  8. A mathematical model for adaptive vein formation during exploratory migration of Physarum polycephalum: routing while scouting

    Science.gov (United States)

    Schenz, Daniel; Shima, Yasuaki; Kuroda, Shigeru; Nakagaki, Toshiyuki; Ueda, Kei-Ichi

    2017-11-01

    Exploring free space (scouting) efficiently is a non-trivial task for organisms of limited perception, such as the amoeboid Physarum polycephalum. However, the strategy behind its exploratory behaviour has not yet been characterised. In this organism, as the extension of the frontal part into free space is directly supported by the transport of body mass from behind, the formation of transport channels (routing) plays the main role in that strategy. Here, we study the organism’s exploration by letting it expand through a corridor of constant width. When turning at a corner of the corridor, the organism constructed a main transport vein tracing a centre-in-centre line. We argue that this is efficient for mass transport due to its short length, and check this intuition with a new algorithm that can predict the main vein’s position from the frontal tip’s progression. We then present a numerical model that incorporates reaction-diffusion dynamics for the behaviour of the organism’s growth front and current reinforcement dynamics for the formation of the vein network in its wake, as well as interactions between the two. The accuracy of the model is tested against the behaviour of the real organism and the importance of the interaction between growth tip dynamics and vein network development is analysed by studying variants of the model. We conclude by offering a biological interpretation of the well-known current reinforcement rule in the context of the natural exploratory behaviour of Physarum polycephalum.

  9. Determination of lead in human calculi and its effects on renal function of lead occupational workers

    International Nuclear Information System (INIS)

    Memon, F.; Vasandani, A.G.M.

    2016-01-01

    Seventy five samples of renal and eighteen samples of supra gingival calculi of lead recycling workers were collected over the period of seven years (2008-2014) and studied for the accumulation of lead. The results were compared with those of non exposed subjects. The lead content of calculi was investigated for its dependence on type and composition of calculi, blood lead, job status and duration of exposure. The effect of blood lead and renal calculi was also investigated in relation to kidney function of respective subjects. The mean lead levels of various types of calculi were found to follow the order as phosphate > oxalate > urate > cystine while single principal group of supra gingival calculi resulted in lower levels of metal. The lead content of calculi positively correlated with phosphate content of both of the renal (r = 0.655) and supra gingival calculi (r= 0.866). Impaired renal function was more pronounced in active workers and depended on blood lead levels in addition to presence of metal in renal calculi. (author)

  10. [Blood lead levels during pregnancy in th the newborn period. Study of the population of Bari].

    Science.gov (United States)

    Carbone, R; Laforgia, N; Crollo, E; Mautone, A; Iolascon, A

    1998-01-01

    Blood lead levels during pregnancy and in neonates immediately after birth have been evaluated, showing higher values in mothers compared to neonates (5.81 +/- 3.05 vs 4.87 +/- 3.60 micrograms/100 ml) and a positive correlation between maternal and neonatal levels (r = 0.82). On the basis of the results derived from the population examined, it has been observed that 6% of newborns have blood lead levels higher than 10 micrograms/100 ml a value recently identified by the Centers for Disease Control (CDC, Atlanta, USA) as a limit for toxicity in children. Moreover, neonatal Pb levels were higher than those found in infants from 6 to 12 months (4.87 +/- 3.60 vs 2.24 +/- 0.54 micrograms/100 ml). During the first week of life there is a steady decrease of blood lead levels, together with increasing renal lead excretion. This study was carried out at the "Dipartimento di Biomedicina dell'Età Evolutiva" University of Bari, southern Italy.

  11. First studies of lead pollution in Guanabara

    International Nuclear Information System (INIS)

    Silveira Branquinho, C.L. da.

    1973-01-01

    The main sources of direct lead intake are studied, and metal concentrations in several medium are examined. Lead was extracted by dithizone in C Cl 4 , being determined by optical spectrophotometry. 2 1 2 Pb was used as a radioactive tracer in low concentration measurements of the metal, and analysis of its 239 KeV peak was done by a Ge-Li detector. In blood samples, the metal was complexed and extracted with APDC in MIBK, being measured by flame less atomic absorption spectrophotometry. Air samples were also collected for periods of 24 hours and 90 minutes. Representative street dust samples were examined, showing a strict correlation with lead in air. It was also estimated the amount of lead in some human blood samples. (author)

  12. [Bidens maximowicziana's adsorption ability and remediation potential to lead in soils].

    Science.gov (United States)

    Wang, Hong-qi; Li, Hua; Lu, Si-jin

    2005-11-01

    Bidens maximowicziana's adsorption ability and remediation potential to lead were studied. The results show: (1) The Bidens maximowicziana has a strong adsorption to lead, the concentration of lead in plants increased linearly with the increase of lead concentration in soil. Then maximum concentration was 1509.3 mg x kg(-1) in roots and 2164.7 mg x kg(-1) in shoots when lead concentration in soil was 2000 mg x L(-1); (2) The lead concentration distribution order in the Bidens maximorwicziana is: leaf>stem>root>seed, which indicate that Bidens maximowicziana has a strong ability to transfer lead; (3) Uptaking ability differes in different vegetal periods. Maximum lead uptaking rate occured in the period of blooming for 40-60 days, in which daily uptake capacity was 15.81 mg x (kg x d)(-1) in roots and 19.83 mg x (kg x d)(-1) in shoots respectively. It can be concluded that Bidens maximowicziana appeares to be a moderate Pb accumulator making it suitable for phytoremediation of Pb contaminated soil.

  13. Glazed clay pottery and lead exposure in Mexico: Current experimental evidence.

    Science.gov (United States)

    Diaz-Ruiz, Araceli; Tristán-López, Luis Antonio; Medrano-Gómez, Karen Itzel; Torres-Domínguez, Juan Alejandro; Ríos, Camilo; Montes, Sergio

    2017-11-01

    Lead exposure remains a significant environmental problem; lead is neurotoxic, especially in developing humans. In Mexico, lead in human blood is still a concern. Historically, much of the lead exposure is attributed to the use of handcrafted clay pottery for cooking, storing and serving food. However, experimental cause-and-effect demonstration is lacking. The present study explores this issue with a prospective experimental approach. We used handcrafted clay containers to prepare and store lemonade, which was supplied as drinking water to pregnant rats throughout the gestational period. We found that clay pots, jars, and mugs leached on average 200 µg/l lead, and exposure to the lemonade resulted in 2.5 µg/dl of lead in the pregnant rats' blood. Neonates also showed increased lead content in the hippocampus and cerebellum. Caspase-3 activity was found to be statistically increased in the hippocampus in prenatally exposed neonates, suggesting increased apoptosis in that brain region. Glazed ceramics are still an important source of lead exposure in Mexico, and our results confirm that pregnancy is a vulnerable period for brain development.

  14. Lead levels in deciduous teeth of children in Yemen

    International Nuclear Information System (INIS)

    Ismail, Rokhsana M.

    2001-01-01

    To determine lead exposure among children in Yemen a total of 280 shed deciduous whole teeth were collected from 269 children. Teeth were analyzed for lead concentrations using atomic absorption spectrophotometry (SP9 Philips) with electrothermal atomization. Children were between 5 and 15 years old. The study period extended from April 1999 to August 2000. The study showed that the overall mean tooth - lead level was 2.15 mg/g dry weight with a range of 0.05-30.4 mg/g dry weight. (author)

  15. Lead levels in deciduous teeth of children in Bahrain.

    Science.gov (United States)

    al-Mahroos, F; al-Saleh, F S

    1997-06-01

    To determine lead exposure among children in Bahrain, a total of 280 shed deciduous whole teeth were collected from 269 children. Teeth were analyzed for lead concentrations using atomic absorption spectrophotometry with electrothermal atomization. Children were between 5 and 15 years old. The study period extended from July 1993 to April 1994. The study showed that the overall mean tooth-lead level was 4.3 micrograms/g dry weight with a range of 0.1-60.8 micrograms/g dry weight. The cumulative frequency distribution revealed that 35% of the teeth had a lead concentration of more than 4 micrograms/g dry weight. The tooth-lead concentrations differed according to the tooth type age. The child's sex, nationality, area of residence and socio-economic status had no impact on tooth-lead level. In conclusion, lead is present in toxic concentrations in 35% of the teeth of the children studied. Urgent measures are needed to eliminate lead from gasoline, paint and other sources in the environment.

  16. Search for Narrow Resonances in Dijet Final States at sqrt[s]=8  TeV with the Novel CMS Technique of Data Scouting.

    Science.gov (United States)

    Khachatryan, V; Sirunyan, A M; Tumasyan, A; Adam, W; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E; Dragicevic, M; Erö, J; Flechl, M; Friedl, M; Frühwirth, R; Ghete, V M; Hartl, C; Hörmann, N; Hrubec, J; Jeitler, M; König, A; Krätschmer, I; Liko, D; Matsushita, T; Mikulec, I; Rabady, D; Rad, N; Rahbaran, B; Rohringer, H; Schieck, J; Strauss, J; Treberer-Treberspurg, W; Waltenberger, W; Wulz, C-E; Mossolov, V; Shumeiko, N; Suarez Gonzalez, J; Alderweireldt, S; De Wolf, E A; Janssen, X; Knutsson, A; Lauwers, J; Van De Klundert, M; Van Haevermaet, H; Van Mechelen, P; Van Remortel, N; Van Spilbeeck, A; Abu Zeid, S; Blekman, F; D'Hondt, J; Daci, N; De Bruyn, I; Deroover, K; Heracleous, N; Lowette, S; Moortgat, S; Moreels, L; Olbrechts, A; Python, Q; Tavernier, S; Van Doninck, W; Van Mulders, P; Van Parijs, I; Brun, H; Caillol, C; Clerbaux, B; De Lentdecker, G; Delannoy, H; Fasanella, G; Favart, L; Goldouzian, R; Grebenyuk, A; Karapostoli, G; Lenzi, T; Léonard, A; Luetic, J; Maerschalk, T; Marinov, A; Randle-Conde, A; Seva, T; Vander Velde, C; Vanlaer, P; Yonamine, R; Zenoni, F; Zhang, F; Cimmino, A; Cornelis, T; Dobur, D; Fagot, A; Garcia, G; Gul, M; Mccartin, J; Poyraz, D; Salva, S; Schöfbeck, R; Tytgat, M; Van Driessche, W; Yazgan, E; Zaganidis, N; Beluffi, C; Bondu, O; Brochet, S; Bruno, G; Caudron, A; Ceard, L; De Visscher, S; Delaere, C; Delcourt, M; Forthomme, L; Francois, B; Giammanco, A; Jafari, A; Jez, P; Komm, M; Lemaitre, V; Magitteri, A; Mertens, A; Musich, M; Nuttens, C; Piotrzkowski, K; Quertenmont, L; Selvaggi, M; Vidal Marono, M; Wertz, S; Beliy, N; Aldá Júnior, W L; Alves, F L; Alves, G A; Brito, L; Correa Martins Junior, M; Hensel, C; Moraes, A; Pol, M E; Rebello Teles, P; Belchior Batista Das Chagas, E; Carvalho, W; Chinellato, J; Custódio, A; Da Costa, E M; Da Silveira, G G; De Jesus Damiao, D; De Oliveira Martins, C; Fonseca De Souza, S; Huertas Guativa, L M; Malbouisson, H; Matos Figueiredo, D; Mora Herrera, C; Mundim, L; Nogima, H; Prado Da Silva, W L; Santoro, A; Sznajder, A; Tonelli Manganote, E J; Vilela Pereira, A; Ahuja, S; Bernardes, C A; Dogra, S; Fernandez Perez Tomei, T R; Gregores, E M; Mercadante, P G; Moon, C S; Novaes, S F; Padula, Sandra S; Romero Abad, D; Ruiz Vargas, J C; Aleksandrov, A; Hadjiiska, R; Iaydjiev, P; Rodozov, M; Stoykova, S; Sultanov, G; Vutova, M; Dimitrov, A; Glushkov, I; Litov, L; Pavlov, B; Petkov, P; Fang, W; Ahmad, M; Bian, J G; Chen, G M; Chen, H S; Chen, M; Chen, Y; Cheng, T; Du, R; Jiang, C H; Leggat, D; Liu, Z; Romeo, F; Shaheen, S M; Spiezia, A; Tao, J; Wang, C; Wang, Z; Zhang, H; Zhao, J; Asawatangtrakuldee, C; Ban, Y; Li, Q; Liu, S; Mao, Y; Qian, S J; Wang, D; Xu, Z; Avila, C; Cabrera, A; Chaparro Sierra, L F; Florez, C; Gomez, J P; González Hernández, C F; Ruiz Alvarez, J D; Sanabria, J C; Godinovic, N; Lelas, D; Puljak, I; Ribeiro Cipriano, P M; Antunovic, Z; Kovac, M; Brigljevic, V; Ferencek, D; Kadija, K; Micanovic, S; Sudic, L; Attikis, A; Mavromanolakis, G; Mousa, J; Nicolaou, C; Ptochos, F; Razis, P A; Rykaczewski, H; Finger, M; Finger, M; Carrera Jarrin, E; Elgammal, S; Mohamed, A; Mohammed, Y; Salama, E; Calpas, B; Kadastik, M; Murumaa, M; Perrini, L; Raidal, M; Tiko, A; Veelken, C; Eerola, P; Pekkanen, J; Voutilainen, M; Härkönen, J; Karimäki, V; Kinnunen, R; Lampén, T; Lassila-Perini, K; Lehti, S; Lindén, T; Luukka, P; Peltola, T; Tuominiemi, J; Tuovinen, E; Wendland, L; Talvitie, J; Tuuva, T; Besancon, M; Couderc, F; Dejardin, M; Denegri, D; Fabbro, B; Faure, J L; Favaro, C; Ferri, F; Ganjour, S; Ghosh, S; Givernaud, A; Gras, P; Hamel de Monchenault, G; Jarry, P; Kucher, I; Locci, E; Machet, M; Malcles, J; Rander, J; Rosowsky, A; Titov, M; Zghiche, A; Abdulsalam, A; Antropov, I; Baffioni, S; Beaudette, F; Busson, P; Cadamuro, L; Chapon, E; Charlot, C; Davignon, O; Granier de Cassagnac, R; Jo, M; Lisniak, S; Miné, P; Naranjo, I N; Nguyen, M; Ochando, C; Ortona, G; Paganini, P; Pigard, P; Regnard, S; Salerno, R; Sirois, Y; Strebler, T; Yilmaz, Y; Zabi, A; Agram, J-L; Andrea, J; 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Andrews, M B; Azzolini, V; Calamba, A; Carlson, B; Ferguson, T; Paulini, M; Russ, J; Sun, M; Vogel, H; Vorobiev, I; Cumalat, J P; Ford, W T; Jensen, F; Johnson, A; Krohn, M; Mulholland, T; Stenson, K; Wagner, S R; Alexander, J; Chaves, J; Chu, J; Dittmer, S; Mirman, N; Nicolas Kaufman, G; Patterson, J R; Rinkevicius, A; Ryd, A; Skinnari, L; Sun, W; Tan, S M; Tao, Z; Thom, J; Tucker, J; Wittich, P; Winn, D; Abdullin, S; Albrow, M; Apollinari, G; Banerjee, S; Bauerdick, L A T; Beretvas, A; Berryhill, J; Bhat, P C; Bolla, G; Burkett, K; Butler, J N; Cheung, H W K; Chlebana, F; Cihangir, S; Cremonesi, M; Elvira, V D; Fisk, I; Freeman, J; Gottschalk, E; Gray, L; Green, D; Grünendahl, S; Gutsche, O; Hare, D; Harris, R M; Hasegawa, S; Hirschauer, J; Hu, Z; Jayatilaka, B; Jindariani, S; Johnson, M; Joshi, U; Klima, B; Kreis, B; Lammel, S; Linacre, J; Lincoln, D; Lipton, R; Liu, T; Lopes De Sá, R; Lykken, J; Maeshima, K; Marraffino, J M; Maruyama, S; Mason, D; McBride, P; Merkel, P; Mrenna, S; Nahn, S; Newman-Holmes, C; O'Dell, V; Pedro, K; Prokofyev, O; Rakness, G; Ristori, L; Sexton-Kennedy, E; Soha, A; Spalding, W J; Spiegel, L; Stoynev, S; Strobbe, N; Taylor, L; Tkaczyk, S; Tran, N V; Uplegger, L; Vaandering, E W; Vernieri, C; Verzocchi, M; Vidal, R; Wang, M; Weber, H A; Whitbeck, A; Acosta, D; Avery, P; Bortignon, P; Bourilkov, D; Brinkerhoff, A; Carnes, A; Carver, M; Curry, D; Das, S; Field, R D; Furic, I K; Konigsberg, J; Korytov, A; Ma, P; Matchev, K; Mei, H; Milenovic, P; Mitselmakher, G; Rank, D; Shchutska, L; Sperka, D; Thomas, L; Wang, J; Wang, S; Yelton, J; Linn, S; Markowitz, P; Martinez, G; Rodriguez, J L; Ackert, A; Adams, J R; Adams, T; Askew, A; Bein, S; Diamond, B; Hagopian, S; Hagopian, V; Johnson, K F; Khatiwada, A; Prosper, H; Santra, A; Weinberg, M; Baarmand, M M; Bhopatkar, V; Colafranceschi, S; Hohlmann, M; Kalakhety, H; Noonan, D; Roy, T; Yumiceva, F; Adams, M R; Apanasevich, L; Berry, D; Betts, R R; Bucinskaite, I; Cavanaugh, R; Evdokimov, O; Gauthier, L; Gerber, C E; Hofman, D J; Kurt, P; O'Brien, C; Sandoval Gonzalez, I D; Turner, P; Varelas, N; Wu, Z; Zakaria, M; Zhang, J; Bilki, B; Clarida, W; Dilsiz, K; Durgut, S; Gandrajula, R P; Haytmyradov, M; Khristenko, V; Merlo, J-P; Mermerkaya, H; Mestvirishvili, A; Moeller, A; Nachtman, J; Ogul, H; Onel, Y; Ozok, F; Penzo, A; Snyder, C; Tiras, E; Wetzel, J; Yi, K; Anderson, I; Blumenfeld, B; Cocoros, A; Eminizer, N; Fehling, D; Feng, L; Gritsan, A V; Maksimovic, P; Osherson, M; Roskes, J; Sarica, U; Swartz, M; Xiao, M; Xin, Y; You, C; Al-Bataineh, A; Baringer, P; Bean, A; Bowen, J; Bruner, C; Castle, J; Kenny, R P; Kropivnitskaya, A; Majumder, D; Mcbrayer, W; Murray, M; Sanders, S; Stringer, R; Tapia Takaki, J D; Wang, Q; Ivanov, A; Kaadze, K; Khalil, S; Makouski, M; Maravin, Y; Mohammadi, A; Saini, L K; Skhirtladze, N; Toda, S; Lange, D; Rebassoo, F; Wright, D; Anelli, C; Baden, A; Baron, O; Belloni, A; Calvert, B; Eno, S C; Ferraioli, C; Gomez, J A; Hadley, N J; Jabeen, S; Kellogg, R G; Kolberg, T; Kunkle, J; Lu, Y; Mignerey, A C; Shin, Y H; Skuja, A; Tonjes, M B; Tonwar, S C; Apyan, A; Barbieri, R; Baty, A; Bi, R; Bierwagen, K; Brandt, S; Busza, W; Cali, I A; Demiragli, Z; Di Matteo, L; Gomez Ceballos, G; Goncharov, M; Gulhan, D; Hsu, D; Iiyama, Y; Innocenti, G M; Klute, M; Kovalskyi, D; Krajczar, K; Lai, Y S; Lee, Y-J; Levin, A; Luckey, P D; Marini, A C; Mcginn, C; Mironov, C; Narayanan, S; Niu, X; Paus, C; Roland, C; Roland, G; Salfeld-Nebgen, J; Stephans, G S F; Sumorok, K; Tatar, K; Varma, M; Velicanu, D; Veverka, J; Wang, J; Wang, T W; Wyslouch, B; Yang, M; Zhukova, V; Benvenuti, A C; Chatterjee, R M; Dahmes, B; Evans, A; Finkel, A; Gude, A; Hansen, P; Kalafut, S; Kao, S C; Klapoetke, K; Kubota, Y; Lesko, Z; Mans, J; Nourbakhsh, S; Ruckstuhl, N; Rusack, R; Tambe, N; Turkewitz, J; Acosta, J G; Oliveros, S; Avdeeva, E; Bartek, R; Bloom, K; Bose, S; Claes, D R; Dominguez, A; Fangmeier, C; Gonzalez Suarez, R; Kamalieddin, R; Knowlton, D; Kravchenko, I; Meier, F; Monroy, J; Siado, J E; Snow, G R; Stieger, B; Alyari, M; Dolen, J; George, J; Godshalk, A; Harrington, C; Iashvili, I; Kaisen, J; Kharchilava, A; Kumar, A; Parker, A; Rappoccio, S; Roozbahani, B; Alverson, G; Barberis, E; Baumgartel, D; Chasco, M; Hortiangtham, A; Massironi, A; Morse, D M; Nash, D; Orimoto, T; Teixeira De Lima, R; Trocino, D; Wang, R-J; Wood, D; Bhattacharya, S; Hahn, K A; Kubik, A; Low, J F; Mucia, N; Odell, N; Pollack, B; Schmitt, M H; Sung, K; Trovato, M; Velasco, M; Dev, N; Hildreth, M; Hurtado Anampa, K; Jessop, C; Karmgard, D J; Kellams, N; Lannon, K; Marinelli, N; Meng, F; Mueller, C; Musienko, Y; Planer, M; Reinsvold, A; Ruchti, R; Rupprecht, N; Smith, G; Taroni, S; Valls, N; Wayne, M; Wolf, M; Woodard, A; Alimena, J; Antonelli, L; Brinson, J; Bylsma, B; Durkin, L S; Flowers, S; Francis, B; Hart, A; Hill, C; Hughes, R; Ji, W; Liu, B; Luo, W; Puigh, D; Rodenburg, M; Winer, B L; Wulsin, H W; Cooperstein, S; Driga, O; Elmer, P; Hardenbrook, J; Hebda, P; Luo, J; Marlow, D; Medvedeva, T; Mooney, M; Olsen, J; Palmer, C; Piroué, P; Stickland, D; Tully, C; Zuranski, A; Malik, S; Barker, A; Barnes, V E; Benedetti, D; Folgueras, S; Gutay, L; Jha, M K; Jones, M; Jung, A W; Jung, K; Miller, D H; Neumeister, N; Radburn-Smith, B C; Shi, X; Sun, J; Svyatkovskiy, A; Wang, F; Xie, W; Xu, L; Parashar, N; Stupak, J; Adair, A; Akgun, B; Chen, Z; Ecklund, K M; Geurts, F J M; Guilbaud, M; Li, W; Michlin, B; Northup, M; Padley, B P; Redjimi, R; Roberts, J; Rorie, J; Tu, Z; Zabel, J; Betchart, B; Bodek, A; de Barbaro, P; Demina, R; Duh, Y T; Ferbel, T; Galanti, M; Garcia-Bellido, A; Han, J; Hindrichs, O; Khukhunaishvili, A; Lo, K H; Tan, P; Verzetti, M; Chou, J P; Contreras-Campana, E; Gershtein, Y; Gómez Espinosa, T A; Halkiadakis, E; Heindl, M; Hidas, D; Hughes, E; Kaplan, S; Kunnawalkam Elayavalli, R; Kyriacou, S; Lath, A; Nash, K; Saka, H; Salur, S; Schnetzer, S; Sheffield, D; Somalwar, S; Stone, R; Thomas, S; Thomassen, P; Walker, M; Foerster, M; Heideman, J; Riley, G; Rose, K; Spanier, S; Thapa, K; Bouhali, O; Castaneda Hernandez, A; Celik, A; Dalchenko, M; De Mattia, M; Delgado, A; Dildick, S; Eusebi, R; Gilmore, J; Huang, T; Juska, E; Kamon, T; Krutelyov, V; Mueller, R; Pakhotin, Y; Patel, R; Perloff, A; Perniè, L; Rathjens, D; Rose, A; Safonov, A; Tatarinov, A; Ulmer, K A; Akchurin, N; Cowden, C; Damgov, J; Dragoiu, C; Dudero, P R; Faulkner, J; Kunori, S; Lamichhane, K; Lee, S W; Libeiro, T; Undleeb, S; Volobouev, I; Wang, Z; Delannoy, A G; Greene, S; Gurrola, A; Janjam, R; Johns, W; Maguire, C; Melo, A; Ni, H; Sheldon, P; Tuo, S; Velkovska, J; Xu, Q; Arenton, M W; Barria, P; Cox, B; Goodell, J; Hirosky, R; Ledovskoy, A; Li, H; Neu, C; Sinthuprasith, T; Sun, X; Wang, Y; Wolfe, E; Xia, F; Clarke, C; Harr, R; Karchin, P E; Lamichhane, P; Sturdy, J; Belknap, D A; Dasu, S; Dodd, L; Duric, S; Gomber, B; Grothe, M; Herndon, M; Hervé, A; Klabbers, P; Lanaro, A; Levine, A; Long, K; Loveless, R; Ojalvo, I; Perry, T; Pierro, G A; Polese, G; Ruggles, T; Savin, A; Sharma, A; Smith, N; Smith, W H; Taylor, D; Verwilligen, P; Woods, N

    2016-07-15

    A search for narrow resonances decaying into dijet final states is performed on data from proton-proton collisions at a center-of-mass energy of 8 TeV, corresponding to an integrated luminosity of 18.8  fb^{-1}. The data were collected with the CMS detector using a novel technique called data scouting, in which the information associated with these selected events is much reduced, permitting collection of larger data samples. This technique enables CMS to record events containing jets at a rate of 1 kHz, by collecting the data from the high-level-trigger system. In this way, the sensitivity to low-mass resonances is increased significantly, allowing previously inaccessible couplings of new resonances to quarks and gluons to be probed. The resulting dijet mass distribution yields no evidence of narrow resonances. Upper limits are presented on the resonance cross sections as a function of mass, and compared with a variety of models predicting narrow resonances. The limits are translated into upper limits on the coupling of a leptophobic resonance Z_{B}^{'} to quarks, improving on the results obtained by previous experiments for the mass range from 500 to 800 GeV.

  17. Leading Indicators of Distress in Danish Banks in the Period 2008-12

    DEFF Research Database (Denmark)

    Buchholst, Birgitte Vølund; Rangvid, Jesper

    Several Danish small and medium-sized banks have become distressed during and after the global financial crisis. In this paper, a multiple logistic regression model is used to identify which factors characterize the distressed Danish banks from 2008-12. The factors are chosen from a broad range...... of variables, i.e. the model is unrestricted. The estimated model identifies the distressed banks fairly well. The variables that altogether best describe the probability of a bank becoming distressed are: a bank's excess capital in per cent of risk weighted assets, the 3 year average lending growth lagged 2...... years, property exposure, and a benchmark for stable funding (the so-called funding-ratio). The variables are all adjusted with the sector average to account for the general development during the period. Based on experiences from this and past crises the Danish FSA introduced the so-called Supervisory...

  18. Evaluating the Protective Effects of Melissa Officinalis on Learning Deficits of Rat’s Offspring Exposed to Lead Acetate During Pre- and Postnatal Periods

    Directory of Open Access Journals (Sweden)

    Z Momeni

    2010-01-01

    Full Text Available Introduction & Objective: Lead contamination dramatically influences different body systems especially the central nervous system. Lead absorption during gestational period has deleterious effects on fetal differentiation and development and it may possibly result in learning deficits in adulthood. Recent studies have demonstrated positive effects of Melissa officinalis on memory improvement in some neural disorders. The aim of the present study is to investigate the protective effects of Melissa on learning deficits in lead acetate exposed rats. Materials & Methods: In this experimental study in department of Biology, Faculty of Sciences, Ferdowsi University of Mashhad (2008-2009, 40 mated Wistar rats were divided into 8 groups as follows: control, negative control (Pb, Melissa (M and Pb+M, and each in 3 different subgroups. The treatment started from the 7th day of gestation and continued during pregnancy and lactation. The learning ability and memory retention of four months old offspring were tested by complex T-maze. The collected data was analyzed by the SPSS software using one-way ANOVA and Toki test. Results: A significant difference was found between lead exposed group and other groups regarding the time to reach the goal and the number of errors while there was no meaningful difference between the control and other experimental groups. Conclusion: In lead exposed rats, learning deficits were obviously noticed. Since there was meaningful difference between control and Pb+M subgroups, Melissa can possibly improve learning deficits in lead acetate exposed rats.

  19. Sandia National Laboratories: About Sandia: Community Involvement

    Science.gov (United States)

    the fascination of science, serving on a Board of Directors, volunteering at a food bank, or giving judging science fairs, coaching sports teams, leading scouting troops, sorting food, building houses, and

  20. Archives of Atmospheric Lead Pollution

    Science.gov (United States)

    Weiss, Dominik; Shotyk, William; Kempf, Oliver

    Environmental archives such as peat bogs, sediments, corals, trees, polar ice, plant material from herbarium collections, and human tissue material have greatly helped to assess both ancient and recent atmospheric lead deposition and its sources on a regional and global scale. In Europe detectable atmospheric lead pollution began as early as 6000years ago due to enhanced soil dust and agricultural activities, as studies of peat bogs reveal. Increased lead emissions during ancient Greek and Roman times have been recorded and identified in many long-term archives such as lake sediments in Sweden, ice cores in Greenland, and peat bogs in Spain, Switzerland, the United Kingdom, and the Netherlands. For the period since the Industrial Revolution, other archives such as corals, trees, and herbarium collections provide similar chronologies of atmospheric lead pollution, with periods of enhanced lead deposition occurring at the turn of the century and since 1950. The main sources have been industry, including coal burning, ferrous and nonferrous smelting, and open waste incineration until c.1950 and leaded gasoline use since 1950. The greatest lead emissions to the atmosphere all over Europe occurred between 1950 and 1980 due to traffic exhaust. A marked drop in atmospheric lead fluxes found in most archives since the 1980s has been attributed to the phasing out of leaded gasoline. The isotope ratios of lead in the various archives show qualitatively similar temporal changes, for example, the immediate response to the introduction and phasing out of leaded gasoline. Isotope studies largely confirm source assessments based on lead emission inventories and allow the contributions of various anthropogenic sources to be calculated.

  1. Childhood lead exposure and uptake in teeth in the Cleveland area during the era of leaded gasoline

    International Nuclear Information System (INIS)

    Robbins, Norman; Zhang, Zhong-Fa; Sun, Jiayang; Ketterer, Michael E.; Lalumandier, James A.; Shulze, Richard A.

    2010-01-01

    Childhood uptake of lead from exposure to atmospheric leaded gasoline in the United States has been studied using mainly blood lead levels. Since reliable blood lead techniques were used only after the peak use of leaded gasoline, the prior exposure history is unclear. The well-documented decline in blood lead levels after the mid-1970s could represent the continuation of a historic steady decline in exposure from many sources. Alternatively, the post-1970s decline might represent the declining phase of a unimodal rise and fall corresponding closely to usage of leaded gasoline. To assess these possibilities, lead concentration and 207Pb/206Pb isotope ratios were measured in the enamel of permanent molar teeth formed between 1936 and 1993 in mainly African-American donors who grew up in the Cleveland area. Tooth enamel preserves the lead concentration and isotope ratio that prevails during tooth formation. Historical trends in enamel lead concentration were significantly correlated with surrogates of atmospheric lead exposure: lead in sediments of two dated Lake Erie cores, and lead consumed in gasoline. About two-thirds of the total lead uptake into enamel in this period was attributable to leaded gasoline, and the remainder to other sources (e.g. paint). Enamel 207Pb/206Pb isotope ratios were similar to those of one lake sediment. Multivariate analysis revealed significant correlation in neighborhoods with higher levels of traffic, and including lake sediment data, accounted for 53% of the variation in enamel lead levels. Enamel lead concentration was highly correlated with reported African-American childhood blood levels. The extrapolated peak level of 48 μg/dL (range 40 to 63) is associated with clinical and behavioral impairments, which may have implications for adults who were children during the peak gasoline lead exposure. In sum, leaded gasoline emission was the predominant source of lead exposure of African-American Cleveland children during the latter

  2. Copper, nickel and lead in lichen and tree bark transplants over different periods of time

    Energy Technology Data Exchange (ETDEWEB)

    Baptista, Mafalda S. [CIIMAR, Rua dos Bragas, 289, 4050-123 Porto (Portugal)], E-mail: abaptista@fc.up.pt; Vasconcelos, M. Teresa S.D. [CIIMAR, Rua dos Bragas, 289, 4050-123 Porto (Portugal); Chemistry Department, Faculty of Sciences, University of Porto, Rua do Campo Alegre, 687, 4169-071 Porto (Portugal)], E-mail: mtvascon@fc.up.pt; Cabral, Joao Paulo [CIIMAR, Rua dos Bragas, 289, 4050-123 Porto (Portugal); Botany Department, Faculty of Sciences, University of Porto, Rua do Campo Alegre, 1191, 4150-181 Porto (Portugal)], E-mail: jpcabral@fc.up.pt; Freitas, M. Carmo [ITN - Technological and Nuclear Institute, Reactor E.N. 10, 2686-953 Sacavem (Portugal)], E-mail: cfreitas@itn.mcies.pt; Pacheco, Adriano M.G. [CVRM-IST - Technical University of Lisbon, Avenida Rovisco Pais, 1, 1049-001 Lisbon (Portugal)], E-mail: apacheco@ist.utl.pt

    2008-01-15

    This work aimed at comparing the dynamics of atmospheric metal accumulation by the lichen Flavoparmelia caperata and bark of Platanus hybrida over different periods of time. Transplants were exposed in three Portuguese coastal cities. Samples were retrieved (1) every 2 months (discontinuous exposure), or (2) after 2-, 4-, 6-, 8- and 10-month periods (continuous exposure), and analysed for Cu, Ni and Pb. Airborne accumulation of metals was essentially independent of climatic factors. For both biomonitors [Pb] > [Ni] > [Cu] but Pb was the only element for which a consistent pattern of accumulation was observed, with the bark outperforming the lichen. The longest exposure periods hardly ever corresponded to the highest accumulation. This might have been partly because the biomonitors bound and released metals throughout the exposure, each with its own dynamics of accumulation, but both according to the environmental metal availability. - Lichen and tree bark have distinct dynamics of airborne metal accumulation.

  3. Copper, nickel and lead in lichen and tree bark transplants over different periods of time

    International Nuclear Information System (INIS)

    Baptista, Mafalda S.; Vasconcelos, M. Teresa S.D.; Cabral, Joao Paulo; Freitas, M. Carmo; Pacheco, Adriano M.G.

    2008-01-01

    This work aimed at comparing the dynamics of atmospheric metal accumulation by the lichen Flavoparmelia caperata and bark of Platanus hybrida over different periods of time. Transplants were exposed in three Portuguese coastal cities. Samples were retrieved (1) every 2 months (discontinuous exposure), or (2) after 2-, 4-, 6-, 8- and 10-month periods (continuous exposure), and analysed for Cu, Ni and Pb. Airborne accumulation of metals was essentially independent of climatic factors. For both biomonitors [Pb] > [Ni] > [Cu] but Pb was the only element for which a consistent pattern of accumulation was observed, with the bark outperforming the lichen. The longest exposure periods hardly ever corresponded to the highest accumulation. This might have been partly because the biomonitors bound and released metals throughout the exposure, each with its own dynamics of accumulation, but both according to the environmental metal availability. - Lichen and tree bark have distinct dynamics of airborne metal accumulation

  4. Public Library YA Program Roundup: Murder, We Wrote...and Played [and] Asleep in the Library: Girl Scouts Earn "From Dreams to Reality" Patch [and] Sign Language Funshop [and] Science Fair Help Day [and] A Skyomish Fairy Tale [and] The POW! Project: Picturing Our World! Teens Create Art and Self-Esteem at the Boston Public Library.

    Science.gov (United States)

    Goldsmith, Francisca; Seblonka, Cathy Sullivan; Wagner, Joyce; Smith, Tammy; Sipos, Caryn; Bodart, Joni Richards

    1998-01-01

    Includes six articles that describe public library programs for teens. Highlights include interactive murder mysteries; a girl scout sleepover program on career awareness; sign language workshop; a Science Fair help day that included guest speakers; a unit on fairy tales and legends; and a project to enhance creativity and self-esteem. (LRW)

  5. Occurrence and determinants of increases in blood lead levels in children shortly after lead hazard control activities

    International Nuclear Information System (INIS)

    Clark, Scott; Grote, JoAnn; Wilson, Jonathan; Succop, Paul; Chen Mei; Galke, Warren; McLaine, Pat

    2004-01-01

    This study is an examination of the effect of lead hazard control strategies on children's blood lead levels immediately after an intervention was conducted as part of the US Department of Housing and Urban Development's Lead-Based Paint Hazard Control Grant Program. Fourteen state and local government grantees participated in the evaluation. The findings indicated an overall average reduction in the blood lead levels of 869 children soon after the implementation of lead hazard controls. However, 9.3% of these children (n=81) had blood lead increases of 5 μg/dL or more. Data routinely collected as part of the evaluation, as well as additional information supplied by the individual programs, were used to determine potential reasons for these observed increases in blood lead. A logistic regression analysis indicated that three principal factors were associated with the blood lead increases: the number of exterior deteriorations present in the child's home (prior to intervention), the educational level of the female parent or guardian of the child, and the child's age. The statistical analysis did not find evidence that children living in households that either did not relocate or relocated for less than the full work period were significantly more likely to have a blood lead increase equal to or greater than 5 μg/dL than children living in households that fully relocated. Statistical analyses also did not reveal any single interior strategy to be more or less likely than others to be associated with a blood lead increase of 5 μg/dL or more

  6. Chronic lead intoxication in calves

    Energy Technology Data Exchange (ETDEWEB)

    Wagenaar, G

    1963-01-01

    Four calves born in the winter of 1961-1962 died on a farm after a disease which had run its course for periods ranging from six weeks to a few months. A calf had also died showing similar symptoms during the previous year. All calves showed identical symptoms. Initially, their liveliness diminished; subsequently, they drank less and showed signs of pica. They finally died after the disease had run its course for about six weeks. The last calf, born late in February 1962, was in poor health as early as May, improved slightly when it had been sent out to grass but died in September, having fallen ill again in August. Autopsy was performed on three calves; all three were affected with chronic interstitial nephritis and uraemic endocarditis of the left auricle was present as well. The results obtained on toxicological investigation were indicative of lead poisoning. The liver of the calf was found to contain two mg of lead per kg, the cortex of the kidney containing twenty-five mg of lead per kg. These figures did not provide direct evidence of lead poisoning, but in evaluating these figures the fact was taken into account that the calf had no longer been able to ingest any lead for several months. Meanwhile, it was found that the stock-owner had fitted an old painted door in the calf-shed, which door was constantly being licked by the calves. The paint contained 18.6% of lead. This finding was followed by examination of the liver of a calf that had died previously. It was found to contain 49.7 mg of lead per kg. Accordingly, the calves had been affected with a form of lead poisoning running a relatively slow course, as a result of which the animals had developed chronic interstitial nephritis. The calves eventually died from uraemia. 4 references.

  7. Subkultura mládeže: Skauting v kulturologické reflexi

    OpenAIRE

    Rambousková, Anna

    2013-01-01

    The bachelor thesis deals with the analysis of the phenomenon of scouting. The aim of this thesis is answer the question, whether scouting can be regarded as a subculture and so contribute to understanding of scouting itself. In first charter terms culture, subculture and youth subculture are defined. Following part presents the organization Scout - association of boy scouts and girl scouts of the Czech Republic. It uses the structure of institution proposed by Bronislaw Malinowski. The main ...

  8. The effect of lead-based paint hazard remediation on blood lead levels of lead poisoned children in New York City.

    Science.gov (United States)

    Leighton, Jessica; Klitzman, Susan; Sedlar, Slavenka; Matte, Thomas; Cohen, Neal L

    2003-07-01

    Despite the widespread use of lead paint hazard control for children with lead poisoning, few controlled studies that estimate the effect of such control on children's blood lead levels have been published. This retrospective follow-up study examined the effects of lead hazard remediation and its timing on the blood lead levels of lead-poisoned children. From the New York City child blood lead registry, 221 children were selected who had an initial blood lead level of 20-44 micro g/dL between 1 July 1994 and 31 December 1996; were 6 months to 6 years of age; had a report of a follow-up blood lead test between 10 and 14 months after the initial test; had a lead-based paint hazard identified in the primary dwelling unit prior to the 10- to 14-month follow-up blood lead test; had resided or spent time at only one address with an identified lead-based paint hazard; and were not chelated. The decline in geometric mean blood lead levels from baseline to 10-14 months later was compared for children whose homes were remediated and whose homes were not remediated during the follow-up period. Regardless of remediation, geometric mean blood lead levels declined significantly from 24.3 micro g/dL at the initial diagnosis to 12.3 micro g/dL at the 10- to 14-month follow-up blood lead test (Premediated the geometric mean blood lead levels declined 53% compared to 41% among the 75 children whose homes were not remediated by the follow-up blood lead test, a remediation effect of approximately 20% (Premediation effect was 11%, although it was no longer significant. Race was the only factor that appeared to confound the relationship: Black children had higher follow-up blood lead levels even after controlling for other factors, including the natural logarithm of the initial blood lead level. The effect of remediation appeared to be stronger for younger (10 to remediation (within less than 3 months) appeared to have greater declines in blood lead levels at the follow-up test than

  9. Lead Leached into Water from Select Plumbing Fixtures” Could Lead to Health Hazard

    Directory of Open Access Journals (Sweden)

    Ramsey Coles

    2014-01-01

    Full Text Available Background: Lead is an inert metal and is resistant to corrosion. It also increases tensile strength of many common materials in daily use. Lead was used during the Roman period to transport water (hence the name plumbing/plumber is common terminology even in the present day. Lead enters the biological system through the air, water, and dust. Fine particles of lead, having diameter less than 5 nm are directly absorbed by lungs. Inorganic lead is absorbed by the gastrointestinal tract, and organic lead is absorbed by the skin. Lead has long been known to be a toxic heavy metal and exposure is associated with many deleterious health effects. Still, lead remains a popular ingredient in products ranging from paint to batteries. The lead content in any given material is estimated using various methods. The least cumbersome method is found to be X-Ray Fluorescence technique (XRF. A portable XRF device was used in the present study. Aim: The main aim of this study to investigate whether lead is present in various commonly used plumbing materials. Material and Methods: All types of branded and commonly used pipes were gathered from a market in Bangalore and tested using the XRF machine. In order to evaluate to what extent lead from the pipes could leach into water, seven pipes were randomly selected and filled with Aquafina water (having undetectable level of lead for a 24 hour period. This water was tested at an NABL accredited laboratory in Bangalore, India for lead content. Result: It was determined that lead was present in many of the samples, at an unacceptable levels ranging from, well above the globally accepted level of 0.01 mg/L proof that lead was able to leach from the samples into water. Conclusions: As lead in drinking water represents a direct pathway for human exposure, the authors recommend that significant measures be taken to prevent use of lead in the plumbing industry for prevention of it’s deleterious effects. Authors have also

  10. on the biochemical indicators of lead poisoning in

    African Journals Online (AJOL)

    N. Sadi

    1 sept. 2017 ... ABSTRACT. This study is conducted to examine the effect of the oral administration of pectin of dates on perturbation of the biochemical parameters induced by lead. Male rats were exposed to lead acetate at 350mg/Kg for one month, after this period, rats treated during one month with the pectin of date at ...

  11. Establishing contract periods

    International Nuclear Information System (INIS)

    Huffman, F.C.

    1978-01-01

    The lead time for executing the Adjustable Fixed-Commitment (AFC) contract and exceptions which may be considered are discussed. The initial delivery period is also discussed. Delays, deferrals, and schedule adjustment charges are finally considered

  12. 76 FR 38650 - Draft Integrated Science Assessment for Lead

    Science.gov (United States)

    2011-07-01

    ... Science Assessment for Lead AGENCY: Environmental Protection Agency. ACTION: Notice of extension of public... Lead'' (EPA/600/R-10/075A). The original Federal Register notice announcing the public comment period... review of the National Ambient Air Quality Standards (NAAQS) for Lead. DATES: The public comment period...

  13. New analytical method for fast nuclide identification in mobile in-situ gamma spectrometers; Neue analytische Methode zur schnellen Nuklididentifikation in mobilen in-situ Gammaspektrometern

    Energy Technology Data Exchange (ETDEWEB)

    Streil, T.; Oeser, V.; Wagner, W. [SARAD GmbH, Dresden (Germany); Doerfel, H.R. [IDEA System GmbH, Karlsruhe (Germany)

    2016-07-01

    Demolition and accidents of nuclear reactors or terroristic attacks may lead to large-area contamination with radionuclides. A suitable mobile measurement equipment should allow a quick overview about the extent of contamination. Recent methods apply for nuclide identification either time-consuming peak-fitting methods inclusive background correction or the so-called trapezoid method determining so-called regions of interest (ROI). Since the nuclide vector is often known, this information can be used as a starting point for the nuclide identification. The presented method uses dynamic smoothing of the registered energy spectrum in accordance with the detector resolution. In this way, noise is effectively suppressed without substantial degradation of the detector resolution. The statistically prepared spectrum is then two-fold differentiated. This provides the peak positions and the two turning points of the found peaks. Nuclide identification is possible using the peak positions, and with the peak and turning point positions and the corresponding values of the spectrum, on may calculate the area of an assumed Gausz distribution without considering the in any case present continuous background. With a 2 x 2'' NaI-detector, as being used in the NucScout device, one can identify a {sup 137}Cs-activity of 200 Bq/kg at distance of 1 m in 10 s. Combined with adapted calibration methods, the algorithm for nuclide identification implemented in the NucScout is also applicable for other geometries, e. g., using a Marinelli cup in the LabScout device.

  14. Electrons and photons in periodic structures

    DEFF Research Database (Denmark)

    Pedersen, Jesper Goor

    . In particular, the modulation leads to the emergence of band gaps, which are accompanied by a strongly modified density of states near and within the band gap. The main focus is on two applications of such modified densities of states. Firstly, the intentional introduction of defects in an otherwise perfectly...... periodic modulation of an electron gas leads to the emergence of localized defect states with energies within the band gap, where no propagating modes exist. Secondly, the divergence of the photonic density of states near a photonic band gap leads to strongly modified light-matter interactions, which has...... of the density of states near the band gap edge. Using a perturbative approach, we demonstrate certain limits of the attainable slow down factors due to broadening of electromagnetic modes. We discuss the effect of damping due to a finite conductivity as well as structural disorder, and provide a common...

  15. The effect of lead-based paint hazard remediation on blood lead levels of lead poisoned children in New York City

    International Nuclear Information System (INIS)

    Leighton, Jessica; Klitzman, Susan; Sedlar, Slavenka; Matte, Thomas; Cohen, Neal L.

    2003-01-01

    Despite the widespread use of lead paint hazard control for children with lead poisoning, few controlled studies that estimate the effect of such control on children's blood lead levels have been published. This retrospective follow-up study examined the effects of lead hazard remediation and its timing on the blood lead levels of lead-poisoned children. From the New York City child blood lead registry, 221 children were selected who had an initial blood lead level of 20-44 μg/dL between 1 July 1994 and 31 December 1996; were 6 months to 6 years of age; had a report of a follow-up blood lead test between 10 and 14 months after the initial test; had a lead-based paint hazard identified in the primary dwelling unit prior to the 10- to 14-month follow-up blood lead test; had resided or spent time at only one address with an identified lead-based paint hazard; and were not chelated. The decline in geometric mean blood lead levels from baseline to 10-14 months later was compared for children whose homes were remediated and whose homes were not remediated during the follow-up period. Regardless of remediation, geometric mean blood lead levels declined significantly from 24.3 μg/dL at the initial diagnosis to 12.3 μg/dL at the 10- to 14-month follow-up blood lead test (P<0.01). Among the 146 children whose homes were remediated the geometric mean blood lead levels declined 53% compared to 41% among the 75 children whose homes were not remediated by the follow-up blood lead test, a remediation effect of approximately 20% (P<0.01). After adjusting for potential confounders, the remediation effect was 11%, although it was no longer significant. Race was the only factor that appeared to confound the relationship: Black children had higher follow-up blood lead levels even after controlling for other factors, including the natural logarithm of the initial blood lead level. The effect of remediation appeared to be stronger for younger (10 to <36 months old) than for older (36

  16. Hydrogen peroxide and central redox theory for aerobic life: A tribute to Helmut Sies: Scout, trailblazer, and redox pioneer.

    Science.gov (United States)

    Jones, Dean P

    2016-04-01

    When Rafael Radi and I wrote about Helmut Sies for the Redox Pioneer series, I was disappointed that the Editor restricted us to the use of "Pioneer" in the title. My view is that Helmut was always ahead of the pioneers: He was a scout discovering paths for exploration and a trailblazer developing strategies and methods for discovery. I have known him for nearly 40 years and greatly enjoyed his collegiality as well as brilliance in scientific scholarship. He made monumental contributions to 20th century physiological chemistry beginning with his first measurement of H2O2 in rat liver. While continuous H2O2 production is dogma today, the concept of H2O2 production in mammalian tissues was largely buried for half a century. He continued this leadership in research on oxidative stress, GSH, selenium, and singlet oxygen, during the timeframe when physiological chemistry and biochemistry transitioned to contemporary 21st century systems biology. His impact has been extensive in medical and health sciences, especially in nutrition, aging, toxicology and cancer. I briefly summarize my interactions with Helmut, stressing our work together on the redox code, a set of principles to link mitochondrial respiration, bioenergetics, H2O2 metabolism, redox signaling and redox proteomics into central redox theory. Copyright © 2015 The Author. Published by Elsevier Inc. All rights reserved.

  17. Almost periodic Hamiltonians: an algebraic approach

    International Nuclear Information System (INIS)

    Bellissard, J.

    1981-07-01

    We develop, by analogy with the study of periodic potential, an algebraic theory for almost periodic hamiltonians, leading to a generalized Bloch theorem. This gives rise to results concerning the spectral measures of these operators in terms of those of the corresponding Bloch hamiltonians

  18. Evolving Trends in Endodontic Research: An Assessment of Published Articles in 2 Leading Endodontic Journals.

    Science.gov (United States)

    Tzanetakis, Giorgos N; Stefopoulos, Spyridon; Loizides, Alexios L; Kakavetsos, Vasileios D; Kontakiotis, Evangelos G

    2015-12-01

    The aim of this study was to evaluate and analyze the evolving trends in endodontic research in 2 leading endodontic journals (ie, Journal of Endodontics and International Endodontic Journal) in articles published from January 2009 to December 2013. The differences in content between this period and a 10-year earlier period from January 1999 to December 2003 were also evaluated. Each journal's content was accessed through the web edition. For each article, the following parameters were recorded: number of authors, article type, number of affiliations, field of study, source of article, and geographic origin. The recorded data were analyzed using both descriptive and analytic statistics. During 2009-2013 (second period), the mean number of authors per article increased significantly compared with 1999-2003 (first period). The main volume of the literature in both periods and journals was original research articles. The number of published reviews increased significantly from the first to the second study period in contrast to case reports/clinical articles, which presented a significant decrease. "Endodontic materials" was the most prevalent thematic category in both study periods. The number of published articles related to "biology" and "chemical preparation and disinfection" increased significantly from the first to the second study period. On the contrary, the number of articles regarding "obturation and microleakage" presented a considerable decrease at the same time. The United States was the leading country in the number of publications in the first period followed by Brazil. In the second period, this rank was reversed with Brazil becoming the leading country followed by the United States. In the last 15 years, the progress of the specialty of endodontology was apparent as shown through the trends and shifts in research orientation in published articles in the 2 leading endodontic journals. The results of the present reviewing process encourage both journals

  19. Use of lead isotopic composition in sulfides for the mineral-formation geochronology

    International Nuclear Information System (INIS)

    Ordynets, G.E.

    1977-01-01

    A study of the isotopic composition of lead in pyrites and galenites of a hydrothermal uranium deposit makes it possible to determine the time of ore formation. A few types of lead ores are distinguished. Each type corresponds to a definite period of mineralization and is characterized by a specific isotopic composition. The Cimmerian age of carbonate-sulphide veins has been established, the deposit being formed over a period of 150-200 million years

  20. Prevalence and Impact of Glenoid Augmentation in American Football Athletes Participating in the National Football League Scouting Combine

    Science.gov (United States)

    Knapik, Derrick M.; Gillespie, Robert J.; Salata, Michael J.; Voos, James E.

    2017-01-01

    Background: Bony augmentation of the anterior glenoid is used in athletes with recurrent shoulder instability and bone loss; however, the prevalence and impact of repair in elite American football athletes are unknown. Purpose: To evaluate the prevalence and impact of glenoid augmentation in athletes invited to the National Football League (NFL) Scouting Combine from 2012 to 2015. Study Design: Case series; Level of evidence, 4. Methods: A total of 1311 athletes invited to the NFL Combine from 2012 to 2015 were evaluated for history of either Bristow or Latarjet surgery for recurrent anterior shoulder instability. Athlete demographics, surgical history, imaging, and physical examination results were recorded using the NFL Combine database. Prospective participation data with regard to draft status, games played, games started, and status after the athletes’ first season in the NFL were gathered using publicly available databases. Results: Surgical repair was performed on 10 shoulders in 10 athletes (0.76%), with the highest prevalence in defensive backs (30%; n = 3). Deficits in shoulder motion were exhibited in 70% (n = 7) of athletes, while 40% (n = 4) had evidence of mild glenohumeral arthritis and 80% demonstrated imaging findings consistent with a prior instability episode (8 labral tears, 2 Hill-Sachs lesions). Prospectively, 40% (n = 4) of athletes were drafted into the NFL. In the first season after the combine, athletes with a history of glenoid augmentation were not found to be at significant risk for diminished participation with regard to games played or started when compared with athletes with no history of glenoid augmentation or athletes undergoing isolated shoulder soft tissue repair. After the conclusion of the first NFL season, 60% (n = 6 athletes) were on an active NFL roster. Conclusion: Despite being drafted at a lower rate than their peers, there were no significant limitations in NFL participation for athletes with a history of glenoid

  1. Prevalence and Impact of Glenoid Augmentation in American Football Athletes Participating in the National Football League Scouting Combine.

    Science.gov (United States)

    Knapik, Derrick M; Gillespie, Robert J; Salata, Michael J; Voos, James E

    2017-08-01

    Bony augmentation of the anterior glenoid is used in athletes with recurrent shoulder instability and bone loss; however, the prevalence and impact of repair in elite American football athletes are unknown. To evaluate the prevalence and impact of glenoid augmentation in athletes invited to the National Football League (NFL) Scouting Combine from 2012 to 2015. Case series; Level of evidence, 4. A total of 1311 athletes invited to the NFL Combine from 2012 to 2015 were evaluated for history of either Bristow or Latarjet surgery for recurrent anterior shoulder instability. Athlete demographics, surgical history, imaging, and physical examination results were recorded using the NFL Combine database. Prospective participation data with regard to draft status, games played, games started, and status after the athletes' first season in the NFL were gathered using publicly available databases. Surgical repair was performed on 10 shoulders in 10 athletes (0.76%), with the highest prevalence in defensive backs (30%; n = 3). Deficits in shoulder motion were exhibited in 70% (n = 7) of athletes, while 40% (n = 4) had evidence of mild glenohumeral arthritis and 80% demonstrated imaging findings consistent with a prior instability episode (8 labral tears, 2 Hill-Sachs lesions). Prospectively, 40% (n = 4) of athletes were drafted into the NFL. In the first season after the combine, athletes with a history of glenoid augmentation were not found to be at significant risk for diminished participation with regard to games played or started when compared with athletes with no history of glenoid augmentation or athletes undergoing isolated shoulder soft tissue repair. After the conclusion of the first NFL season, 60% (n = 6 athletes) were on an active NFL roster. Despite being drafted at a lower rate than their peers, there were no significant limitations in NFL participation for athletes with a history of glenoid augmentation when compared with athletes without a history of shoulder

  2. Chaotic behavior of current-carrying plasmas in external periodic oscillations

    Energy Technology Data Exchange (ETDEWEB)

    Ohno, Noriyasu; Tanaka, Masayoshi; Komori, Akio; Kawai, Yoshinobu

    1989-01-01

    A set of cascading bifurcations and a chaotic state in the presence of an external periodic oscillation are experimentally investigated in a current-carrying plasma. The measured bifurcation sequence leading to chaos, which is controlled by changing plasma densities and the frequencies of external oscillations, is in qualitative agreement with a theory which describes anharmonic systems in periodic fields. (author).

  3. An exploratory study of lead recovery in lead-acid battery lifecycle in US market: An evidence-based approach

    International Nuclear Information System (INIS)

    Genaidy, A.M.; Sequeira, R.; Tolaymat, T.; Kohler, J.; Rinder, M.

    2008-01-01

    Background: This research examines lead recovery and recycling in lead-acid batteries (LAB) which account for 88% of US lead consumption. We explore strategies to maximize lead recovery and recycling in the LAB lifecycle. Currently, there is limited information on recycling rates for LAB in the published literature and is derived from a single source. Therefore, its recycling efforts in the US has been unclear so as to determine the maximum opportunities for metal recovery and recycling in the face of significant demands for LAB particularly in the auto industry. Objectives: The research utilizes an evidence-based approach to: (1) determine recycling rates for lead recovery in the LAB product lifecycle for the US market; and (2) quantify and identify opportunities where lead recovery and recycling can be improved. Methods: A comprehensive electronic search of the published literature was conducted to gather information on different LAB recycling models and actual data used to calculate recycling rates based on product lifecycle for the US market to identify strategies for increasing lead recovery and recycling. Results: The electronic search yielded five models for calculating LAB recycling rates. The description of evidence was documented for each model. Furthermore, an integrated model was developed to identify and quantify the maximum opportunities for lead recovery and recycling. Results showed that recycling rates declined during the period spanning from 1999 to 2006. Opportunities were identified for recovery and recycling of lead in the LAB product lifecycle. Concluding remarks: One can deduce the following from the analyses undertaken in this report: (1) lead recovery and recycling has been stable between 1999 and 2006; (2) lead consumption has increased at an annual rate of 2.25%, thus, the values derived in this study for opportunities dealing with lead recovery and recycling underestimate the amount of lead in scrap and waste generated; and (3) the

  4. Dietary and inhalation intake of lead and estimation of blood lead levels in adults and children in Kanpur, India.

    Science.gov (United States)

    Sharma, Mukesh; Maheshwari, Mayank; Morisawa, S

    2005-12-01

    This research was initiated to study lead levels in various food items in the city of Kanpur, India, to assess the dietary intake of lead and to estimate blood lead (PbB) levels, a biomarker of lead toxicity. For this purpose, sampling of food products, laboratory analysis, and computational exercises were undertaken. Specifically, six food groups (leafy vegetables, nonleafy vegetables, fruits, pulses, cereals, and milk), drinking water, and lead air concentration were considered for estimating lead intake. Results indicated highest lead content in leafy vegetables followed by pulses. Fruits showed low lead content and drinking water lead levels were always within tolerable limits. It was estimated that average daily lead intake through diet was about 114 microg/day for adults and 50 microg/day in children; tolerable limit is 250 microg/day for adults and 90 microg/day for children. The estimated lead intakes were translated into the resultant PbB concentrations for children and adults using a physiologically-based pharmacokinetic (PBPK) model. Monte Carlo simulation of PbB level variations for adults showed that probability of exceeding the tolerable limit of PbB (i.e.,10 microg/dL) was 0.062 for the pre-unleaded and 0.000328 for the post-unleaded gasoline period. The probability of exceeding tolerable limits in PbB level was reduced by a factor of 189 in the post-unleaded scenario. The study also suggested that in spite of the introduction of unleaded gasoline, children continue to be at a high risk (probability of exceeding 10 microg/dL = 0.39) because of a high intake of lead per unit body weight.

  5. Testing for lead in toys at day care centers.

    Science.gov (United States)

    Sanders, Martha; Stolz, Julie; Chacon-Baker, Ashley

    2013-01-01

    Exposure to lead-based paint or material has been found to impact children's cognitive and behavioral development at blood lead levels far below current standards. The purpose of the project was to screen for lead in toy items in daycare centers in order to raise awareness of inside environmental lead exposures and minimize lead-based exposures for children. Occupational therapy students in a service learning class tested for lead in ten daycare or public centers using the XRF Thermo Scientific Niton XL3t, a method accepted by the Consumer Product Safety Commission (CPSC). A total of 460 items were tested over a two-month period for an average of 66 toys per setting. Fifty six (56) items tested > 100 ppm, which represented 12% of the entire sample. Items with high lead levels included selected toys constructed with lead-based paint, lead metals, plastics using lead as a color enhancer, and decorative objects. While the actual number of lead-based products is small, the cumulative exposure or habitual use may pose an unnecessary risk to children. Indoor exposures occurred for all day care centers regardless of socio-economic levels. Recommendations to minimize exposures are provided.

  6. Atmospheric deposition of lead in Norway: spatial and temporal variation in isotopic composition

    International Nuclear Information System (INIS)

    Steinnes, E.; Aaberg, G.; Hjelmseth, H.

    2005-01-01

    Moss samples collected from 22 sites all over Norway at five different times during 1977-2000 were analysed for stable lead isotope ratios. These data together with total lead concentrations and relevant literature lead isotope data from UK, western/central Europe and eastern Europe/Russia were used to elucidate major source regions for lead deposited in different parts of the country at different times. The southernmost part of the country was most affected from western/central Europe around 1975, but the deposition declined rapidly and UK became a more significant source region in the 1980s. Recently, the influence is mostly from Eastern Europe. In the west, UK was the dominant source region during the whole period. In the middle and northern regions, the deposition was low but also decreasing regularly, and the main source region was probably the North Atlantic. In the far north-east, influence from Russia and eastern Europe was dominant during the whole period

  7. Are There Dangerous Levels of Lead in Local Soil?

    Science.gov (United States)

    Pita, I.

    2017-12-01

    The purpose of this experiment was to show that comparing random soil samples from areas in New Orleans; the Garden District will have the highest levels of lead in soil. My Independent variable was the soil samples collected from locations in the Garden District area of New Orleans, and other locations throughout New Orleans. The control was the soil samples collected from the local playground in the New Orleans area. My dependent variable was the lead soil test kit, using ppm (parts per million) of lead to show concentration. 400 ppm + in bare soil where children play is considered dangerous hazard levels. 1,000 + ppm in all other areas is considered dangerous hazard levels. The first step to my experiment, I collected soil samples from different locations throughout the Garden District area of New Orleans. The second step to my experiment, I conducted the lead soil testing in a controlled area at home in a well ventilated room, using all the necessary safety equipment needed, I began testing a 24 hour test period and a 48 hour test period. I then collected the data from both test. The results showed that soil samples from the Garden District area compared to the other sample locations had higher lead concentrations in the soil. This backed my hypothesis when comparing soil samples from areas in New Orleans, the Garden District will have the highest lead levels. In conclusion these experiments showed that with the soil samples collected, there were higher concentrations of lead in the soil from the Garden District area compared to the other areas where soil was collected. Reconstruction and renovations, from the devastation that Hurricane Katrina created, are evident of the lead in paint of older homes which now show the lead concentration in the soil. Lead is a lethal element if consumed or inhaled in high doses, which can damage key organs in our body, which can be deadly. Better awareness through social media, television, radio, doctors, studies, pamphlets

  8. Implementing reduced-risk integrated pest management in fresh-market cabbage: improved net returns via scouting and timing of effective control.

    Science.gov (United States)

    Burkness, Eric C; Hutchison, W D

    2008-04-01

    During 1998-2001, field studies were done to assess the efficacy of an integrated pest management (IPM) program using an action threshold and "reduced-risk" insecticides. The IPM program was compared with a conventional grower-based program. Program performance was evaluated based on management of Trichoplusia ni (Hiibner), Pieris (=Artogeia) rapae (L.), and Plutella xylostella (L.), as well as the economic impact of each program on net returns. The action threshold used in the IPM program consisted of 10% plants infested with T. ni larvae, based on previous small-plot experiment station trials. In all years of the study, the IPM program resulted in significantly lower percentages of plants infested than the conventional program or untreated check. The mean reduction in insecticide applications for the IPM program compared with the conventional program was 23.5%, whereas, on average, the costs of the IPM program were 46.0% higher than the conventional program. Pest reduction in the IPM program resulted in an average of 10.5% higher marketable yields than the conventional program. Percentages of marketable heads in the IPM program ranged from 82 to 99% and from 63 to 96% in the conventional program. Mean net returns for the IPM program exceeded the conventional program by $984.20/ha. These results indicated that the IPM program reduced insecticide use overall, even though costs of the IPM program, with either spinosad or indoxacarb, were sometimes higher. Overall, net returns of the IPM program were higher due to active pest scouting, improved application timing, and increases in marketable yield. Given the potential decrease in insecticide applications and increases in net profit resulting from this IPM program, additional analyses should be conducted to quantify the economic risk, or consistency of the results, to fully evaluate the benefits of the IPM program compared with a conventional program.

  9. Influence of minerals on lead-induced alterations in liver function in rats exposed to long-term lead exposure

    International Nuclear Information System (INIS)

    Herman, D'souza Sunil; Geraldine, Menezes; T, Venkatesh

    2009-01-01

    The objective of this study was to evaluate the role of minerals on lead-induced effect on the liver. Differentiation of minerals and heavy metals pose an inherent problem due to certain common properties shared by them. With this approach to the problem of heavy metal toxicity, in the present study two groups of male Wistar albino rats, one group (well-nourished) fed on mineral rich diet and other group (undernourished) fed on diet without mineral supplements were used. Both the groups of rats were subjected to long-term lead exposure. The diet of well-nourished group was supplemented with calcium (Ca); 1.2%, phosphorous (P); 0.6%, iron (Fe); 90 mg/kg, zinc (Zn); 50 mg/kg, magnesium (Mg); 0.08%, manganese (Mn); 70 mg/kg, selenium (Se); 0.2 mg/kg, copper (Cu); 5 mg/kg, molybdenum (Mo); 0.8 mg/kg, iodine (I); 0.6 mg/kg, cobalt (Co); 3.0 mg/kg. Their blood lead and parameters of liver function were monitored periodically. Results of the study showed a very high statistically significant increase (p < 0.001) in the blood lead (PbB) levels and liver function test parameters in the undernourished subjects compared to the well-nourished subjects. Nutritional management of lead poisoning is of importance since essential elements and toxic heavy metals may interact to minimize the absorption of lead.

  10. Influence of minerals on lead-induced alterations in liver function in rats exposed to long-term lead exposure

    Energy Technology Data Exchange (ETDEWEB)

    Herman, D' souza Sunil, E-mail: hermansdsouza@rediffmail.com [Department of Biotechnology, Manipal Life Sciences Centre, KMC, Manipal University, Manipal (India); Geraldine, Menezes, E-mail: gere1@rediffmail.com [Department of Biochemistry and Biophysics, St. John' s Medical College, Koramangala, Bangalore 560034, Karnataka (India); T, Venkatesh, E-mail: venky_tv@hotmail.com [Department of Biochemistry and Biophysics, St. John' s Medical College, Koramangala, Bangalore 560034, Karnataka (India)

    2009-07-30

    The objective of this study was to evaluate the role of minerals on lead-induced effect on the liver. Differentiation of minerals and heavy metals pose an inherent problem due to certain common properties shared by them. With this approach to the problem of heavy metal toxicity, in the present study two groups of male Wistar albino rats, one group (well-nourished) fed on mineral rich diet and other group (undernourished) fed on diet without mineral supplements were used. Both the groups of rats were subjected to long-term lead exposure. The diet of well-nourished group was supplemented with calcium (Ca); 1.2%, phosphorous (P); 0.6%, iron (Fe); 90 mg/kg, zinc (Zn); 50 mg/kg, magnesium (Mg); 0.08%, manganese (Mn); 70 mg/kg, selenium (Se); 0.2 mg/kg, copper (Cu); 5 mg/kg, molybdenum (Mo); 0.8 mg/kg, iodine (I); 0.6 mg/kg, cobalt (Co); 3.0 mg/kg. Their blood lead and parameters of liver function were monitored periodically. Results of the study showed a very high statistically significant increase (p < 0.001) in the blood lead (PbB) levels and liver function test parameters in the undernourished subjects compared to the well-nourished subjects. Nutritional management of lead poisoning is of importance since essential elements and toxic heavy metals may interact to minimize the absorption of lead.

  11. Periodic instantons and scattering amplitudes

    International Nuclear Information System (INIS)

    Khlebnikov, S.Yu.; Rubakov, V.A.; Tinyakov, P.G.

    1991-04-01

    We discuss the role of periodic euclidean solutions with two turning points and zero winding number (periodic instantons) in instanton induced processes below the sphaleron energy E sph . We find that the periodic instantons describe certain multiparticle scattering events leading to the transitions between topologically distinct vacua. Both the semiclassical amplitudes and inital and final states of these transitions are determined by the periodic instantons. Furthermore, the corresponding probabilities are maximal among all states of given energy. We show that at E ≤ E sph , the periodic instantons can be approximated by infinite chains of ordinary instantons and anti-instantons, and they naturally emerge as deformations of the zero energy instanton. In the framework of 2d abelian Higgs model and 4d electroweak theory we show, however, that there is not obvious relation between periodic instantons and two-particle scattering amplitudes. (orig.)

  12. Vlasov dynamics of periodically driven systems

    Science.gov (United States)

    Banerjee, Soumyadip; Shah, Kushal

    2018-04-01

    Analytical solutions of the Vlasov equation for periodically driven systems are of importance in several areas of plasma physics and dynamical systems and are usually approximated using ponderomotive theory. In this paper, we derive the plasma distribution function predicted by ponderomotive theory using Hamiltonian averaging theory and compare it with solutions obtained by the method of characteristics. Our results show that though ponderomotive theory is relatively much easier to use, its predictions are very restrictive and are likely to be very different from the actual distribution function of the system. We also analyse all possible initial conditions which lead to periodic solutions of the Vlasov equation for periodically driven systems and conjecture that the irreducible polynomial corresponding to the initial condition must only have squares of the spatial and momentum coordinate. The resulting distribution function for other initial conditions is aperiodic and can lead to complex relaxation processes within the plasma.

  13. Relative effects of climate and source strength on atmospheric lead concentrations in Auckland, New Zealand

    Science.gov (United States)

    Power, H. C.; de Freitas, C. R.; Hay, J. E.

    1992-06-01

    Atmospheric lead levels were examined to assess the consequences of the 46 percent reduction in the lead content of premium grade petrol in New Zealand. Since this change was implemented in July 1986 observed levels of atmospheric lead decreased by 38 percent, but all or part of this reduction may have been due to factors other than fluctuations in lead emissions, notably variations in climate. Analysis of detailed atmospheric lead, meteorological and traffic data measured contemporaneously provided insight into the atmospheric processes influencing lead levels in Auckland and formed the basis of a statistical model capable of predicting monthly lead concentrations. The model was used to predict lead levels in Auckland for the period July 1986 through to July 1989 in the absence of any reduction in the lead content of petrol. Comparison with values observed for the same period showed that all of the reduction in atmospheric lead levels since July 1986 can be attributed to the reduction in the lead content of petrol. Policy planning implications of such a finding are considered.

  14. Lead poisoning in whooper and tundra swans.

    Science.gov (United States)

    Nakade, Tetsuya; Tomura, Yoshihiro; Jin, Kazuo; Taniyama, Hiroyuki; Yamamoto, Mutsuki; Kikkawa, Aya; Miyagi, Kunitaro; Uchida, Eiji; Asakawa, Mitsuhiko; Mukai, Takeshi; Shirasawa, Masahiko; Yamaguchi, Mamoru

    2005-01-01

    Six weak whooper swans (Cygnus cygnus) and two weak tundra swans (Cygnus columbianus) were found at Swamp Miyajima (Hokkaido, Japan) in May 1998. Anorexia, depression, green watery feces, pale conjunctiva, and anemia were observed. Radiographs showed from six to 38 suspected lead pellets in the gizzard. Blood lead concentrations were 2.5-6.7 microg/g (mean+/-SD=4.6+/-1.14 microg/g) on day 1. After blood collection, the birds were treated with calcium disodium ethylenediaminetetraacetate (CaEDTA) given intravenously and force fed. Despite treatment, seven birds died the next day. Green, bile-stained livers and pale or green kidneys were observed on necropsy. Microscopically, bile pigment was widespread in the liver and acid-fast intranuclear inclusion bodies were observed in renal tubular epithelium. Lead concentrations in livers and kidneys were 14.0-30.4 microg/g and 30.2-122 microg/g wet weight, respectively. Only one bird survived and this whooper swan continued to be treated with CaEDTA and activated charcoal. No lead shot was observed in the proventriculus and gizzard by radiography on day 64 and the blood lead concentration decreased from 2.9 microg/g to 0.09 microg/g during that same period. After 4 mo of rehabilitation, the whooper swan was returned to the wild. Lead intoxication continues to be a problem at Swamp Miyajima.

  15. Non-equilibrium Green's functions method: Non-trivial and disordered leads

    Science.gov (United States)

    He, Yu; Wang, Yu; Klimeck, Gerhard; Kubis, Tillmann

    2014-11-01

    The non-equilibrium Green's function algorithm requires contact self-energies to model charge injection and extraction. All existing approaches assume infinitely periodic leads attached to a possibly quite complex device. This contradicts today's realistic devices in which contacts are spatially inhomogeneous, chemically disordered, and impacting the overall device characteristics. This work extends the complex absorbing potentials method for arbitrary, ideal, or non-ideal leads in atomistic tight binding representation. The algorithm is demonstrated on a Si nanowire with periodic leads, a graphene nanoribbon with trumpet shape leads, and devices with leads of randomly alloyed Si0.5Ge0.5. It is found that alloy randomness in the leads can reduce the predicted ON-state current of Si0.5Ge0.5 transistors by 45% compared to conventional lead methods.

  16. Nonparametric Inference for Periodic Sequences

    KAUST Repository

    Sun, Ying

    2012-02-01

    This article proposes a nonparametric method for estimating the period and values of a periodic sequence when the data are evenly spaced in time. The period is estimated by a "leave-out-one-cycle" version of cross-validation (CV) and complements the periodogram, a widely used tool for period estimation. The CV method is computationally simple and implicitly penalizes multiples of the smallest period, leading to a "virtually" consistent estimator of integer periods. This estimator is investigated both theoretically and by simulation.We also propose a nonparametric test of the null hypothesis that the data have constantmean against the alternative that the sequence of means is periodic. Finally, our methodology is demonstrated on three well-known time series: the sunspots and lynx trapping data, and the El Niño series of sea surface temperatures. © 2012 American Statistical Association and the American Society for Quality.

  17. Effects of CaEDTA injection on lead, zinc, copper and ALAD in erythrocyte, plasma and urine in lead-exposed workers: a 24-h observation

    Energy Technology Data Exchange (ETDEWEB)

    Aono, H.; Araki, S.

    1984-01-01

    To evaluate the effects of calcium disodium ethylenediamine tetraacetate (CaEDTA) on the concentrations of lead, zinc and copper in plasma, erythrocyte and urine, and the delta-aminolevulinic acid dehydratase (ALAD) activity in erythrocyte, we administered CaEDTA in 1-h intravenous infusion to ten male gun metal founders with blood-lead concentration of 39 to 64 micrograms/dl (mean 49 micrograms/dl). We found that the plasma concentration of lead, following a rapid rise within the first 3 h, fell temporarily to the level significantly lower than the initial level 19 h after start of the infusion. The plasma concentration of zinc fell to the minimal level 5 h after the infusion; and the erythrocyte concentration of zinc and the ALAD activity concurrently rose to the maximal level 5 h after the infusion. By contrast, no significant alteration was observed in the concentrations of copper in plasma and erythrocyte. The maximal level of urinary metal excretion was attained during the period between 1 and 2 h after start of CaEDTA infusion for lead; within 2 h for zinc; and between 2 and 4 h for copper. The urinary metal excretion returned to the initial level 14 to 24 h after infusion for zinc and copper; but lead excretion was still higher than the initial level during this period. The difference in the kinetics of the three metals following CaEDTA injection is discussed in the light of these findings.

  18. Interaction between periodic in-service inspection requirements and design

    International Nuclear Information System (INIS)

    Prot, A.C.; Saglio, R.

    1979-03-01

    After reviewing the requirements specific of periodic In-Service Inspection related to safety problems, especially for the pressure vessels, and taking into account the experience gained with several PWR reactors, the authors show these requirements could lead to modify the primary circuit design

  19. The decreasing period of AG Phe

    International Nuclear Information System (INIS)

    Cerruti, M.A.

    1986-01-01

    Seven UBV photoelectric times of minimum light are presented. They shift the photographically known period 0 . d 613 to 0 . d 380. The improvement of the light elements leads to a reliable shortening of the period. A rough determination of the mass-ratio permitted to give an estimate of the mass transfer in the system. 13 refs., 1 fig., 1 tab. (author)

  20. Shock dynamics in layered periodic media

    KAUST Repository

    Ketcheson, David I.

    2012-01-01

    Solutions of constant-coeffcient nonlinear hyperbolic PDEs generically develop shocks, even if the initial data is smooth. Solutions of hyperbolic PDEs with variable coeffcients can behave very differently. We investigate formation and stability of shock waves in a one-dimensional periodic layered medium by a computational study of time-reversibility and entropy evolution. We find that periodic layered media tend to inhibit shock formation. For small initial conditions and large impedance variation, no shock formation is detected even after times much greater than the time of shock formation in a homogeneous medium. Furthermore, weak shocks are observed to be dynamically unstable in the sense that they do not lead to significant long-term entropy decay. We propose a characteristic condition for admissibility of shocks in heterogeneous media that generalizes the classical Lax entropy condition and accurately predicts the formation or absence of shocks in these media.

  1. Dactylifera L) on the biochemical indicators of lead poisoning in ...

    African Journals Online (AJOL)

    This study is conducted to examine the effect of the oral administration of pectin of dates on perturbation of the biochemical parameters induced by lead. Male rats were exposed to lead acetate at 350mg/Kg for one month, after this period, rats treated during one month with the pectin of date at 3%. Rats were sacrificed, the ...

  2. In vivo x-ray fluorescence of bone lead in the study of human lead metabolism: Serum lead, whole blood lead, bone lead, and cumulative exposure

    International Nuclear Information System (INIS)

    Cake, K.M.; Chettle, D.R.; Webber, C.E.; Gordon, C.L.

    1995-01-01

    Traditionally, clinical studies of lead's effect on health have relied on blood lead levels to indicate lead exposure. However, this is unsatisfactory because blood lead levels have a half-life of approximately 5 weeks, and thus reflect recent exposure. Over 90% of the lead body burden is in bone, and it is thought to have a long residence time, thus implying that measurements of bone lead reflect cumulative exposure. So, measurements of bone lead are useful in understanding the long-term health effects of lead. Ahlgren reported the first noninvasive measurements of bone lead in humans, where γ-rays from 57 Co were used to excite the K series x-rays of lead. The lead detection system at McMaster University uses a 109 Cd source which is positioned at the center of the detector face (HPGe) and a near backscatter (∼160 degrees) geometry. This arrangement allows great flexibility, since one can sample lead in a range of different bone sites due to a robust normalization technique which eliminates the need to correct for bone geometry, thickness of overlying tissue, and other related factors. The effective radiation dose to an adult during an x-ray fluorescence bone lead measurement is extremely low, being 35 nSv. This paper addresses the issue of how bone, whole blood, and serum lead concentrations can be related in order to understand a person's lead exposure history

  3. Superconducting magnets and leads thereto

    International Nuclear Information System (INIS)

    Biltcliffe, M.N.; Hanley, P.E.; McKinnon, J.B.; Wheatley, R.W.

    1975-01-01

    The magnet described comprises a cryostat containing a superconducting coil for the generation of a magnetic field, with a short-circuiting superconducting link connected across the coil, and electrical leads extending through the cryostat to the coil; these leads are provided with joints within the cryostat to enable them to be detached from the coil and removed from the cryostat without interrupting the current through the coil, thus reducing heat conduction to the cryostat through the leads. The joints are arranged so that the leads can be readily detached and re-attached to the coil from outside the cryostat. Gas-tight seals are provided where the leads pass through the outer wall of the cryostat, with caps that can be secured after removal of the leads. This kind of magnet can provide a stable magnetic field continuously over long periods, such as is required in nuclear magnetic resonance spectrometers. (U.K.)

  4. The effects of CaEDTA injection on lead, zinc, copper and ALAD in erythrocyte, plasma and urine in lead-exposed workers: a 24-h observation.

    Science.gov (United States)

    Aono, H; Araki, S

    1984-01-01

    To evaluate the effects of calcium disodium ethylenediamine tetraacetate (CaEDTA) on the concentrations of lead, zinc and copper in plasma, erythrocyte and urine, and the delta-aminolevulinic acid dehydratase (ALAD) activity in erythrocyte, we administered CaEDTA in 1-h intravenous infusion to ten male gun metal founders with blood-lead concentration of 39 to 64 micrograms/dl (mean 49 micrograms/dl). We found that the plasma concentration of lead, following a rapid rise within the first 3 h, fell temporarily to the level significantly lower than the initial level 19 h after start of the infusion. The plasma concentration of zinc fell to the minimal level 5 h after the infusion; and the erythrocyte concentration of zinc and the ALAD activity concurrently rose to the maximal level 5 h after the infusion. By contrast, no significant alteration was observed in the concentrations of copper in plasma and erythrocyte. The maximal level of urinary metal excretion was attained during the period between 1 and 2 h after start of CaEDTA infusion for lead; within 2 h for zinc; and between 2 and 4 h for copper. The urinary metal excretion returned to the initial level 14 to 24 h after infusion for zinc and copper; but lead excretion was still higher than the initial level during this period. The difference in the kinetics of the three metals following CaEDTA injection is discussed in the light of these findings.

  5. Water quality criteria for lead

    Energy Technology Data Exchange (ETDEWEB)

    Nagpal, N.K.

    1987-01-01

    This report is one in a series that establishes water quality criteria for British Columbia. The report sets criteria for lead to protect a number of water uses, including drinking water, freshwater and marine aquatic life, wildlife, livestock, irrigation, and recreation. The criteria are set as either maximum concentrations of total lead that should not be exceeded at any time, or average concentrations that should not be exceeded over a 30-day period. Actual values are summarized.

  6. Leaching of cadmium, chromium, copper, lead, and zinc from two slag dumps with different environmental exposure periods under dynamic acidic condition.

    Science.gov (United States)

    Jin, Zhisheng; Liu, Taoze; Yang, Yuangen; Jackson, Daniel

    2014-06-01

    Over the past few decades, zinc smelting activities in Guizhou, China have produced numerous slag dumps, which are often dispersed on roadsides and hill slopes throughout the region. During periods of acid rain, these exposed slags release heavy metals into surface water bodies. A column leaching study was designed to test the potential release of the heavy metals cadmium (Cd), chromium (Cr), copper (Cu), lead (Pb), and zinc (Zn) under simulated acid rain events. Two slags with varying environmental exposure periods were packed in columns and subjected to leaching solutions of pH 3.5, 5.5, or DI H2O at intervals of 1, 7, 14, 28, 56d. Pulse concentrations of Cd in leachate were found above 5μg/L, Cr, Pb, and Zn >10μg/L, whereas, Cu reached 10μg/L. After five leaching events, the leachability (percentage of cumulative heavy metal leached after five leaching events as in its respective total concentration in slags) of Cd was 0.05 percent and 0.035 percent from the old and young slag, respectively. Cr (0.035 percent and 0.05 percent) was greater than Cu (0.002 percent and 0.005 percent) and Zn (0.006 percent and 0.003 percent), while the lowest leachability was observed for Pb (0.0005 percent and 0.0002 percent) from the old and young slags, respectively. Reaction rates (release amount of heavy metals in certain period of leaching) of heavy metals in the leachates demonstrated the sequence of Zn>Cr>Cd, Cu>Pb. Leaching release of heavy metals was jointly affected by the pH of leaching solution and mineral composition of slags (including chemical forms of Cd, Cr, Cu, Pb, and Zn). Environmental exposure period of slags, resulting in the alteration of minerals, could affect the release process of heavy metals in leaching as well. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Waves in periodic medium. Atomic matter waves in light crystals

    International Nuclear Information System (INIS)

    Oberthaler, M. K.

    1997-07-01

    This work deals with the propagation of matter waves inside a periodic potential. In analogy to photon optics a potential can be described by a refractive index for matter waves. A real potential leads to a refractive spatial structure while an imaginary potential leads to an absorptive structure. A general theoretical description is given in the framework of Floquet theory. The equivalent approach of dynamical diffraction theory will be treated in detail. The analytic solution for weak potentials are given in a general form so that they are applicable for every kind of wave and medium. For our experiments an open two level atom (metastable Argon) propagating inside a standing light wave was used. Detuning the frequency of the light wave from the atomic resonance leads to a real (refractive) periodic potential. Tuning the laser exact on resonance gives rise to a pure imaginary (absorptive) periodic potential. In analogy to solid state crystals in X-ray and neutron optics we call a standing light wave a light crystal. Tuning the standing light field on resonance we demonstrated experimentally the Borrmann effect. This effect describes the increase of the total transmission through a crystal for Bragg incidence. Furthermore, we confirmed that this effect is coherent and that a sinusoidal wave field is formed inside the crystal. The nodes of the wave field were found to coincide with the maxima of absorption. For a detuned standing light field a refractive crystal was realized, for which the expected Pendelloesung effect was demonstrated. In this case the maximum of the wave field inside the crystal was found at the steepest gradient of the potential as predicted by dynamical diffraction theory. Superposing an absorptive and a refractive light crystal a complex light crystal was realized. With such a crystal the violation of Friedel's law was demonstrated in a very clear way. (author)

  8. Factors affecting the absorption and excretion of lead in the rat

    International Nuclear Information System (INIS)

    Conrad, M.E.; Barton, J.C.

    1978-01-01

    A reliable method for studying lead absorption and excretion in rats is described. Lead absorption occurs primarily in the duodenum where lead enters the epithelial mucosal cells. There is a relative mucosal block for lead with increasing intraluminal doses. Certain substances which bind lead and increase its solubility enhance its absorption. Iron, zinc, and calcium decrease the absorption of lead without affecting its solubility, probably by competing for shared absorptive receptors in the intestinal mucosa. The total body burden of lead does not affect lead absorption. Thus, lead does not have a feedback mechanism which limits absorption. Lead absorption is increased during rapid periods of growth and in iron-deficient animals. It is diminished with starvation and in iron-overloaded animals. The excretion and kinetics of tracer doses of radiolead were quantified. Erythrocytes seem to serve an important role in transport. Excretion occurs in urine and stool. Bile is an important route of excretion in the gut. Although most of a tracer dose is rapidly excreted, the excretory process is limited permitting lead accumulation primarily in bone

  9. Period doubling in a model of magnetoconvection with Ohmic heating

    International Nuclear Information System (INIS)

    Osman, M. B. H.

    2000-01-01

    In this work it has been studied an idealized model of rotating nonlinear magneto convection to investigate the effects of Ohmic heating. In the over stable region it was found that Ohmic heating can lead to a period-doubling sequence

  10. Periodic flow patterns of the magnetic fluid in microchannel

    International Nuclear Information System (INIS)

    Chang, C.-W.; Cheng, Y.-T.; Tsai, C.-Y.; Chien, J.-H.; Wang, P.-Y.; Chen, P.-H.

    2007-01-01

    In this study, of interests are the periodic flow patterns of the oil-based magnetic fluid in microchannels. A microfluidic chip is made of poly-dimethylsiloxane (PDMS) and contains cross-shape microchannels. The microchannels are 1000 μm in width and 200 μm in depth. A syringe pump was used to drive the fluids. Periodic flow patterns were seen and the slugs of magnetic fluid and DI water were generated. The operating factors discussed in the present work are the flow rates and the magnetic field. The frequency of generation of the slugs increases with increase in the flow rates. Besides, by settling the permanent magnet around the microchannel, the periods of the slug generation are changed. Different positions of the magnet lead to different periods for generating the slugs. By adjusting operating conditions, to control the frequency and the volume of the slugs is practical

  11. Sub-nanometer periodic nonlinearity error in absolute distance interferometers

    Science.gov (United States)

    Yang, Hongxing; Huang, Kaiqi; Hu, Pengcheng; Zhu, Pengfei; Tan, Jiubin; Fan, Zhigang

    2015-05-01

    Periodic nonlinearity which can result in error in nanometer scale has become a main problem limiting the absolute distance measurement accuracy. In order to eliminate this error, a new integrated interferometer with non-polarizing beam splitter is developed. This leads to disappearing of the frequency and/or polarization mixing. Furthermore, a strict requirement on the laser source polarization is highly reduced. By combining retro-reflector and angel prism, reference and measuring beams can be spatially separated, and therefore, their optical paths are not overlapped. So, the main cause of the periodic nonlinearity error, i.e., the frequency and/or polarization mixing and leakage of beam, is eliminated. Experimental results indicate that the periodic phase error is kept within 0.0018°.

  12. Writing about the World -Danish Suffragettes’ International Engagement as framed in Suffragette Periodicals

    DEFF Research Database (Denmark)

    Fiig, Christina

    ’s organizations and suffragette organizations in the period of 1900-1915 leading up to the universal enfranchisement. As these Danish periodicals have not previously been subject to much research, the analysis draws on research based on British and American suffragette periodicals and feminist print media (Di......Cenzo, Delap & Ryan 2011).The analysis documents that the periodicals offer a window for understanding the suffragettes’ political engagement with and reflections on the “internationalization of feminism”....

  13. Lead accumulation in the aquatic fern Azolla filiculoides.

    Science.gov (United States)

    Oren Benaroya, Rony; Tzin, Vered; Tel-Or, Elisha; Zamski, Eli

    2004-01-01

    In this study, we characterized lead (Pb2+) accumulation and storage by the aquatic fern Azolla filiculoides. Lead precipitates were detected in the vacuoles of mesophyll cells of Azolla plants cultured for 6 d in rich growth medium containing 20 mg l(-1) Pb2+. Energy dispersive spectroscopy (EDS) analysis of the relative element content of leaves collected from these plants revealed a 100% increase in the levels of P, S, Na and Ca and a 40% decrease in Mg and Cl compared to the untreated plants. Both Azolla whole plants and isolated apoplasts were incubated for 6 d in 20 mg l(-1) Pb2+. Lead content in the whole plant composed 0.37%, 2.3% and 1.8% of the dry weight after 2, 4 and 6 d of growth, respectively, while the isolated Azolla apoplast contained 0.125%, 1.22% and 1.4% Pb2+, respectively. Lead content in Azolla whole plant increase by 200%, 100% and 22% after 2, 4 and 6 d of growth, respectively, when compared to Azolla apoplast. Dark, electron dense deposits of lead were observed in light and transmission electron microscope in leaf cells treated with lead. All the observed lead deposits were localized in vacuoles while larger lead deposits were found in mature leaves than in young leaves. No lead deposits were found in cells of the cyanobiont Anabaena when the plants were exposed to similar conditions. Activity and content of V-H+-ATPase were studied in Azolla plants grown in the presence of 20, 40 and 80 mg l(-1) of lead for a period of 4 d. Activity of V-H+-ATPase was increased by 190%, 210% and 220%, respectively, but the content of V-H+-ATPase was reduced by all lead concentrations. Copyright 2004 Elsevier SAS

  14. Multiple bifurcations and periodic 'bubbling' in a delay population model

    International Nuclear Information System (INIS)

    Peng Mingshu

    2005-01-01

    In this paper, the flip bifurcation and periodic doubling bifurcations of a discrete population model without delay influence is firstly studied and the phenomenon of Feigenbaum's cascade of periodic doublings is also observed. Secondly, we explored the Neimark-Sacker bifurcation in the delay population model (two-dimension discrete dynamical systems) and the unique stable closed invariant curve which bifurcates from the nontrivial fixed point. Finally, a computer-assisted study for the delay population model is also delved into. Our computer simulation shows that the introduction of delay effect in a nonlinear difference equation derived from the logistic map leads to much richer dynamic behavior, such as stable node → stable focus → an lower-dimensional closed invariant curve (quasi-periodic solution, limit cycle) or/and stable periodic solutions → chaotic attractor by cascading bubbles (the combination of potential period doubling and reverse period-doubling) and the sudden change between two different attractors, etc

  15. Effect of the first night shift period on sleep in young nurse students.

    Science.gov (United States)

    Fietze, Ingo; Knoop, Karsten; Glos, Martin; Holzhausen, Martin; Peter, Jan Giso; Penzel, Thomas

    2009-12-01

    In young hospital nurses being exposed to a night shift work schedule for the first time in their occupational life, sleep quality is investigated quantitatively. A main sleep period and supplementary sleep periods were defined and analyzed to investigate sleep behavior and quality. A total of 30 young nurses (26 women, 4 men), mean age 20.2 +/- 2.1 years participated. A 3 week nursing school period was followed by a 3 week work period with a 3-5 night shift sub-period and recovery days. Sleep-wake behavior was assessed with an actigraph, sleep diaries, Epworth sleepiness scale (ESS), and quality of life was assessed with a standard questionnaire (SF-36). Comparing the school period with the work shift period when excluding recovery days after night shift period significant increase of total sleep time within 24 h was found during the work days (ANOVA P night shift sub-period, there was just a small decline of the main sleep period at day (n.s.) which was not compensated by supplementary sleep episodes. The supplementary sleep during work day varied between 11 min (school period) and 18 min after recovery days from night shift (n.s.). Young healthy nurses tolerate the first night shift exposure very well, according to objective and subjective parameters related to quality of sleep. An increased sleep need during work days lead to longer total sleep time, but do not lead to longer supplementary sleep episodes. Young nurses tolerate the first rotating shift period and the first night shift period very well.

  16. A longitudinal study of the effects of long-term exposure to lead among lead battery factory workers in Taiwan (1989-1999)

    Energy Technology Data Exchange (ETDEWEB)

    Hsiao, Chun-Yin; Wu, Hong-Dar Isaac; Lai, Jim-Shoung; Kuo, Hsien-Wen [Institute of Environmental Health, China Medical College, No 91, Hsueh-Shin Rd., Taichung, Taiwan (China)

    2001-11-12

    The objective of this study was to assess the relationship between blood-lead levels (BLL), hematological, liver and renal indicators among workers in a lead battery factory in Taiwan over a 10-year period. Blood samples were taken periodically from 30 workers and BLL, HGB (hemoglobin), RBC (red blood cells), WBC (white blood cells) and HCT (hematocrit) were measured. Levels of GPT (alanine aminotransferase) and Crea (creatinine) in the blood were assessed to indicate liver and renal function, respectively. The results showed that there was a general decrease in BLL over the 10-year period (except for 1993). There was a similar trend for HCT, RBC and Crea. There was no significant trend for the other health indicators. Four generalized estimating equation (GEE) models [correlation model (A), threshold correlation model (B), instant change model (C) and lag change model (D)] were set up to demonstrate the causal relationship between BLL and the other health indicators. Models A and C showed that BLL correlated positively with RBC, but negatively with Crea. Model B showed that BLL correlated positively with GPT. There were no significant correlations of BLL with the other indicators. Models C and D, (GEE with logit link function to analyze the association between changes BLL and the other health indicators) showed that when BLL increased, RBC and HCT increased, both longitudinally and cross-sectionally. The authors conclude that long-term exposure to lead stimulates production of RBC and HCT, but the effect on liver and renal function was unclear.

  17. Thyrotoxic periodic paralysis

    International Nuclear Information System (INIS)

    Ferreiro, J.E.; Arguelles, D.J.; Rams, H. Jr.

    1986-01-01

    A case of thyrotoxic periodic paralysis is reported in a Hispanic man with an unusual recurrence six weeks after radioactive iodine treatment. Thyrotoxic periodic paralysis has now been well characterized in the literature: it occurs primarily in Orientals with an overwhelming male preponderance and a higher association of specific HLA antigens. Clinical manifestations include onset after high carbohydrate ingestion or heavy exertion, with progressive symmetric weakness leading to flaccid paralysis of the extremities and other muscle groups, lasting several hours. If hypokalemia is present, potassium administration may help abort the attack. Although propranolol can be efficacious in preventing further episodes, the only definitive treatment is establishing a euthyroid state. The pathophysiology is still controversial, but reflects altered potassium and calcium dynamics as well as certain morphologic characteristics within the muscle unit itself

  18. Lead dust in broken hill homes--a potential hazard for young children?

    Science.gov (United States)

    Boreland, F; Lyle, D M; Wlodarczyk, J; Balding, W A; Reddan, S

    2002-01-01

    To determine the potential hazard posed by indoor lead dust to young children in Broken Hill, a silver-lead-zinc mining town in outback Australia, and the degree to which lead flux is influenced by factors such as geographical location, house construction type and condition. 116 homes were selected and 93 (80%) studied from 10 localities in Broken Hill during the spring of 1995. Lead flux was measured using 85 mm diameter polystyrene petri dishes. Dishes were placed in four rooms of each house to collect dust over a six-to-eight-week period. Data on the location, condition and construction type of each house were recorded. Multiple linear regression was used to determine predictors of lead flux. Flux data were log transformed for the analysis. Average household lead flux varied nearly seven-fold across districts from a low of 166 (distant from the mines), to a high of 1,104 microg/m2/30-day period (adjacent to the mines). Houses that were 'adequately sealed' had 2.9 times the lead flux, and 'poorly sealed' houses 4.3 times the flux, of 'very well sealed' houses. Construction material did not significantly affect these flux levels, and no statistically significant interactions were found between house condition and location or house type. Many Broken Hill homes have high levels of lead flux that pose a potential risk to young children. Quantification of this hazard provides useful information for the community that can help focus efforts on actions required to minimise lead dust in the home. Household dust is a potential source of lead for young children in at-risk communities. Information on lead flux in homes can assist these communities and public health agencies to better understand and deal more effectively with the problem.

  19. Comparison of lead removal behaviors and generation of water-soluble sodium compounds in molten lead glass under a reductive atmosphere

    Science.gov (United States)

    Okada, Takashi; Nishimura, Fumihiro; Xu, Zhanglian; Yonezawa, Susumu

    2018-06-01

    We propose a method of reduction-melting at 1000 °C, using a sodium-based flux, to recover lead from cathode-ray tube funnel glass. To recover the added sodium from the treated glass, we combined a reduction-melting process with a subsequent annealing step at 700 °C, generating water-soluble sodium compounds in the molten glass. Using this combined process, this study compares lead removal behavior and the generation of water-soluble sodium compounds (sodium silicates and carbonates) in order to gain fundamental information to enhance the recovery of both lead and sodium. We find that lead removal increases with increasing melting time, whereas the generation efficiency of water-soluble sodium increases and decreases periodically. In particular, near 90% lead removal, the generation of water-soluble sodium compounds decreased sharply, increasing again with the prolongation of melting time. This is due to the different crystallization and phase separation efficiencies of water-soluble sodium in molten glass, whose structure continuously changes with lead removal. Previous studies used a melting time of 60 min in the processes. However, in this study, we observe that a melting time of 180 min enhances the water-soluble sodium generation efficiency.

  20. Developmental immunotoxicology of lead

    International Nuclear Information System (INIS)

    Dietert, Rodney R.; Lee, Ji-Eun; Hussain, Irshad; Piepenbrink, Michael

    2004-01-01

    The heavy metal, lead, is a known developmental immunotoxicant that has been shown to produce immune alterations in humans as well as other species. Unlike many compounds that exert adverse immune effects, lead exposure at low to moderate levels does not produce widespread loss of immune cells. In contrast, changes resulting from lead exposure are subtle at the immune cell population level but, nevertheless, can be functionally dramatic. A hallmark of lead-induced immunotoxicity is a pronounced shift in the balance in T helper cell function toward T helper 2 responses at the expense of T helper 1 functions. This bias alters the nature and range of immune responses that can be produced thereby influencing host susceptibility to various diseases. Immunotoxic responses to lead appear to differ across life stages not only quantitatively with regard to dose response, but also qualitatively in terms of the spectrum of immune alterations. Experimental studies in several lab animal species suggest the latter stages of gestation are a period of considerable sensitivity for lead-induced immunotoxicity. This review describes the basic characteristics of lead-induced immunotoxicity emphasizing experimental animal results. It also provides a framework for the consideration of toxicant exposure effects across life stages. The existence of and probable basis for developmental windows of immune hyper-susceptibility are presented. Finally, the potential for lead to serve as a perinatal risk factor for childhood asthma as well as other diseases is considered

  1. Discrete changes of current statistics in periodically driven stochastic systems

    International Nuclear Information System (INIS)

    Chernyak, Vladimir Y; Sinitsyn, N A

    2010-01-01

    We demonstrate that the counting statistics of currents in periodically driven ergodic stochastic systems can show sharp changes of some of its properties in response to continuous changes of the driving protocol. To describe this effect, we introduce a new topological phase factor in the evolution of the moment generating function which is akin to the topological geometric phase in the evolution of a periodically driven quantum mechanical system with time-reversal symmetry. This phase leads to the prediction of a sign change for the difference of the probabilities to find even and odd numbers of particles transferred in a stochastic system in response to cyclic evolution of control parameters. The driving protocols that lead to this sign change should enclose specific degeneracy points in the space of control parameters. The relation between the topology of the paths in the control parameter space and the sign changes can be described in terms of the first Stiefel–Whitney class of topological invariants. (letter)

  2. Lead-iron phosophate glass

    International Nuclear Information System (INIS)

    Sales, B.C.; Boatner, L.A.

    1988-01-01

    The lead-iron phosphate nuclear waste glasses (LIPNWG) are the subject of the present chapter. They were discovered in 1984 while the authors were attempting to find a sintering aid for certain types of crystalline monazite ceramic high-level nuclear waste forms. In the present chapter, the term waste glass is synonymous with nuclear waste glass (NWG), and the acronym LIP is often used for lead-iron phosphate. Lead-iron phosphate glasses, like many of the previously studied phosphate glasses, are corrosion resistant in aqueous solutions at temperatures below 100 degrees C, and they can be melted and poured at temperatures that are relatively low in comparison with the processing temperatures required for current silicate glass compositions. Unlike the phosphate glasses investigated previously, however, LIPNWGs do not suffer from alteration due to devitrification during realistic and readily, achievable cooling periods. Additionally, lead-iron phosphate glass melts are not nearly as corrosive as the sodium phosphate melts investigated during the 1960s; and, therefore, they can be melted and processed using crucibles made from a variety of materials

  3. Quantized gauge invariant periodic TDHF solutions

    International Nuclear Information System (INIS)

    Kan, K.-K.; Griffin, J.J.; Lichtner, P.C.; Dworzecka, M.

    1979-01-01

    Time-dependent Hartree-Fock (TDHF) is used to study steady state large amplitude nuclear collective motions, such as vibration and rotation. As is well known the small amplitude TDHF leads to the RPA equation. The analysis of periodicity in TDHF is not trivial because TDHF is a nonlinear theory and it is not known under what circumstances a nonlinear theory can support periodic solutions. It is also unknown whether such periodic solution, if they exist, form a continuous or a discrete set. But, these properties may be important in obtaining the energy spectrum of the collective states from the TDHF description. The periodicity and Gauge Invariant Periodicity of solutions are investigated for that class of models whose TDHF solutions depend on time through two parameters. In such models TDHF supports a continuous family of periodic solutions, but only a discrete subset of these is gauge invariant. These discrete Gauge Invariant Periodic solutions obey the Bohr-Summerfeld quantization rule. The energy spectrum of the Gauge Invariant Periodic solutions is compared with the exact eigenergies in one specific example

  4. Sigmoid Volvulus Complicating Postpartum Period

    Directory of Open Access Journals (Sweden)

    Kelsey E. Ward

    2017-01-01

    Full Text Available Background. Sigmoid volvulus is a rare complication of pregnancy and the puerperium. Case. A 19-year-old patient, gravida 1 para 0 at 41 0/7 weeks of gestation, admitted for late-term induction of labor underwent an uncomplicated primary low transverse cesarean delivery for arrest of descent. Her postoperative period was complicated by sudden onset of abdominal pain and the ultimate diagnosis of sigmoid volvulus. Conclusion. Prompt surgical evaluation of an acute abdomen in the postpartum period is essential; delayed diagnosis and treatment can lead to significant maternal morbidity and mortality.

  5. Recovery of slowed nerve conduction velocity in lead-exposed workers

    Energy Technology Data Exchange (ETDEWEB)

    Araki, S.; Honma, T.; Yanagihara, S.; Ushio, K.

    1980-06-01

    Maximum motor nerve conduction velocities in the median nerve (MCV) and blood lead (PbB) were repeatedly measured in 14 lead-exposed workers with an initial PbB from 0.7 to 4.0 ..mu..mol/kg (median 2.3 ..mu..mol/kg) for a period from 3 months to 7 years: A certain dose of Calcium Disodium Ethylenediaminetetraacetic Acid (CaEDTA) was injected intravenously into most of the subjects during the period. In seven subjects, MCV improved by more than 4 m/s during the observation period which involved the first two successive measurements of MCV and PbB, but the remaining seven subjects showed the minimal alteration (within +- 4.0 m/s). The initial value of MCV was significantly slower (P < 0.01) and the decrease in PbB was significantly greater (P < 0.05) in the group of subjects having shown the improvement of MCV by more than 4 m/s. The initial value of MCV was significant in determining the alteration in MCV in multiple regression analysis and, together with the change in PbB, explained 31% of the alteration in MCV between the first two successive measurements. The initial level of PbB, dose of CaEDTA, time interval between the measurements and age played no essential part in the alteration in MCV. The alteration in MCV throughout the whole observational period in each subject significantly correlated with the concurrent change in PbB (r = -0.573, P < 0.001).

  6. Linear and nonlinear stability of periodic orbits in annular billiards

    Science.gov (United States)

    Dettmann, Carl P.; Fain, Vitaly

    2017-04-01

    An annular billiard is a dynamical system in which a particle moves freely in a disk except for elastic collisions with the boundary and also a circular scatterer in the interior of the disk. We investigate the stability properties of some periodic orbits in annular billiards in which the scatterer is touching or close to the boundary. We analytically show that there exist linearly stable periodic orbits of an arbitrary period for scatterers with decreasing radii that are located near the boundary of the disk. As the position of the scatterer moves away from a symmetry line of a periodic orbit, the stability of periodic orbits changes from elliptic to hyperbolic, corresponding to a saddle-center bifurcation. When the scatterer is tangent to the boundary, the periodic orbit is parabolic. We prove that slightly changing the reflection angle of the orbit in the tangential situation leads to the existence of Kolmogorov-Arnold-Moser islands. Thus, we show that there exists a decreasing to zero sequence of open intervals of scatterer radii, along which the billiard table is not ergodic.

  7. Availability of periodically tested systems

    International Nuclear Information System (INIS)

    Signoret, J.P.

    1979-01-01

    There is at the present time a need in accurate models to asess the availability of periodically tested stand-by systems. This paper shows how to improve the well known 'saw-tooth curve' model in order to take into account various reliability parameters. A model is developed to assess the pointwise and the mean availabilities of periodically tested stand-by systems. Exact and approxination formulae are given. In addition, the model developed herein leads to optimize the test interval in order to minimize the mean unavailability. A safety diesel in a nuclear power plant is given as an example

  8. Log-periodic dipole antenna with low cross-polarization

    DEFF Research Database (Denmark)

    Pivnenko, Sergey

    2006-01-01

    In this work, log-periodic antennas with improved cross-polarization level were studied. It was found that some modifications of the traditional design lead to an essential improvement of the co-to-cross polarization ratio up to 40 dB. An improved design of a log-periodic dipole antenna with low...

  9. PREVENTION OF NIPPLE CRACKS OF THE MAMMARY GLAND IN THE EARLY POSTNATAL PERIOD

    Directory of Open Access Journals (Sweden)

    Marina L. Travina

    2017-01-01

    Full Text Available Preservation and prolongation of the lactation period is not only a guarantee of the child's full physical and mental development but also one of the most important methods for reducing the risk of developing breast cancer. Problems with the mammary gland nipple in a woman in the early postnatal period lead to a refusal of lactation. We carried out a retrospective analysis (period from 2010 to 2016 of the causes of traumatizing mammary gland nipples in the early postnatal period in 172 women (mean age 29.1 ± 4.3 years. Methods of prevention and treatment of nipple injuries in the early postnatal period have been offered for the lactation period prolongation.

  10. Non-equilibrium Green's functions method: Non-trivial and disordered leads

    International Nuclear Information System (INIS)

    He, Yu; Wang, Yu; Klimeck, Gerhard; Kubis, Tillmann

    2014-01-01

    The non-equilibrium Green's function algorithm requires contact self-energies to model charge injection and extraction. All existing approaches assume infinitely periodic leads attached to a possibly quite complex device. This contradicts today's realistic devices in which contacts are spatially inhomogeneous, chemically disordered, and impacting the overall device characteristics. This work extends the complex absorbing potentials method for arbitrary, ideal, or non-ideal leads in atomistic tight binding representation. The algorithm is demonstrated on a Si nanowire with periodic leads, a graphene nanoribbon with trumpet shape leads, and devices with leads of randomly alloyed Si 0.5 Ge 0.5 . It is found that alloy randomness in the leads can reduce the predicted ON-state current of Si 0.5 Ge 0.5 transistors by 45% compared to conventional lead methods

  11. Four-atom period in the conductance of monatomic al wires

    DEFF Research Database (Denmark)

    Thygesen, Kristian Sommer; Jacobsen, Karsten Wedel

    2003-01-01

    We present first-principles calculations based on density functional theory for the conductance of monatomic Al wires between Al(111) electrodes. In contrast to the even-odd oscillations observed in other metallic wires, the conductance of the Al wires is found to oscillate with a period of four ...... atoms as the length of the wire is varied. Although local charge neutrality can account for the observed period, it leads to an incorrect phase. We explain the conductance behavior using a resonant transport model based on the electronic structure of the infinite wire....

  12. Polysheroidal periodic functions

    International Nuclear Information System (INIS)

    Truskova, N.F.

    1985-01-01

    Separation of variables in the Helmholtz N-dimensional (N≥4) equation in polyspheroidal coordinate systems leads to the necessity of solving equations going over into equations for polyspheroidal periodic functions used for solving the two-centre problem in quantum mechanics, the three-body problem with Coulomb interaction, etc. For these functions the expansions are derived in terms of the Jacobi polynomials and Bessel functions. Their basic properties, asymptotics are considered. The algorithm of their computer calculations is developed. The results of numerical calculations are given

  13. Stable lead isotopes in environmental health with emphasis on human investigations

    International Nuclear Information System (INIS)

    Gulson, Brian

    2008-01-01

    There has been widespread use of stable lead isotopes in the earth sciences for more than 40 years focussed on the origin and age of rocks and minerals with lesser application in environmental investigations where the emphasis has been directed typically to the source of lead in environmental media such as air, water and soils. In contrast, the number of environmental health investigations focussed on humans (and primates) is limited in spite of the demonstrated utility of the approach in pioneering studies in the early 1970's. This paper reviews the status of lead isotopes in human investigations especially over the past 2 decades, the period over which most activity has taken place. Following a brief introduction to the method, examples are provided illustrating the use of lead isotopes in a wide spectrum of activities including sources and pathways of lead in diverse environments from urban to mining communities, various applications associated with pregnancy, the contribution of bone lead to blood lead including in the elderly, the half-life of lead in blood, and lead in bones and other media. A brief outline of critical research on non-human primates is also given. The lead isotope method is a powerful technique for tracing lead and could be employed more widely in human investigations

  14. Anthropogenic impact and lead pollution throughout the Holocene in Southern Iberia.

    Science.gov (United States)

    García-Alix, A; Jimenez-Espejo, F J; Lozano, J A; Jiménez-Moreno, G; Martinez-Ruiz, F; García Sanjuán, L; Aranda Jiménez, G; García Alfonso, E; Ruiz-Puertas, G; Anderson, R Scott

    2013-04-01

    Present day lead pollution is an environmental hazard of global proportions. A correct determination of natural lead levels is very important in order to evaluate anthropogenic lead contributions. In this paper, the anthropogenic signature of early metallurgy in Southern Iberia during the Holocene, more specifically during the Late Prehistory, was assessed by mean of a multiproxy approach: comparison of atmospheric lead pollution, fire regimes, deforestation, mass sediment transport, and archeological data. Although the onset of metallurgy in Southern Iberia is a matter of controversy, here we show the oldest lead pollution record from Western Europe in a continuous paleoenvironmental sequence, which suggests clear lead pollution caused by metallurgical activities since ~3900 cal BP (Early Bronze Age). This lead pollution was especially important during Late Bronze and Early Iron ages. At the same time, since ~4000 cal BP, an increase in fire activity is observed in this area, which is also coupled with deforestation and increased erosion rates. This study also shows that the lead pollution record locally reached near present-day values many times in the past, suggesting intensive use and manipulation of lead during those periods in this area. Copyright © 2013 Elsevier B.V. All rights reserved.

  15. Depression of hyperglycemic response to glucagon by parenteral lead administration in sheep

    Energy Technology Data Exchange (ETDEWEB)

    Brockman, R P

    1978-01-01

    The insulin and glucose responses to glucagon infusions (27 ..mu..g/hr) were determined in sheep before and after parenteral lead treatment (6 mg/kg intravenously). Glucose production was measured by primed continuous infusion of (6-/sup 3/H)glucose. Glucagon and insulin concentrations before and during glucagon infusions were not significantly different between lead treatment and control experiments. Lead administration did not affect the concentration or production of glucose in the preinfusion period. However, depressed hyperglycemia during glucagon infusion in lead treated experiments tended to be associated with decreased glucose production. The reduced glucogenic response to glucagon may be the result of reduced function of pyruvate carboxylase, a key hepatic gluconeogenic enzyme in sheep, from lead induced impairment of mitochondrial function. 21 references, 1 figure.

  16. Lead exposure potentiates predatory attack behavior in the cat.

    Science.gov (United States)

    Li, Wenjie; Han, Shenggao; Gregg, Thomas R; Kemp, Francis W; Davidow, Amy L; Louria, Donald B; Siegel, Allan; Bogden, John D

    2003-07-01

    Epidemiologic studies have demonstrated that environmental lead exposure is associated with aggressive behavior in children; however, numerous confounding variables limit the ability of these studies to establish a causal relationship. The study of aggressive behavior using a validated animal model was used to test the hypothesis that there is a causal relationship between lead exposure and aggression in the absence of confounding variables. We studied the effects of lead exposure on a feline model of aggression: predatory (quiet biting) attack of an anesthetized rat. Five cats were stimulated with a precisely controlled electrical current via electrodes inserted into the lateral hypothalamus. The response measure was the predatory attack threshold current (i.e., the current required to elicit an attack response on 50% of the trials). Blocks of trials were administered in which predatory attack threshold currents were measured three times a week for a total of 6-10 weeks, including before, during, and after lead exposure. Lead was incorporated into cat food "treats" at doses of 50-150 mg/kg/day. Two of the five cats received a second period of lead exposure. Blood lead concentrations were measured twice a week and were cats and increased after the cessation of lead exposure in four of the five cats (Pcat were inversely correlated (r=-0.35 to -0.74). A random-effects mixed model demonstrated a significant (P=0.0019) negative association between threshold current and blood lead concentration. The data of this study demonstrate that lead exposure enhances predatory aggression in the cat and provide experimental support for a causal relationship between lead exposure and aggressive behavior in humans.

  17. Lead poisoning in small animals

    Energy Technology Data Exchange (ETDEWEB)

    Scott, H M

    1963-08-17

    During the period 1957 to 1959 a considerable number of dogs were seen which were suffering from colic. Colic is not normally a condition commonly encountered in the dog, and the number of cases seen was large in proportion to the number of dogs in the population concerned. A number of other dogs exhibited nervous signs which varied from symptoms of mild anxiety to exaggerated fits. There was a certain amount of overlapping between the 2 groups in that some cases which originally only showed signs of colic later progressed to the stage where they showed nervous symptoms. The following report deals with 28 cases of lead poisoning in dogs and cats which occurred at Broken Hill, Northern Rhodesia. 8 references, 4 tables.

  18. Time optimized path-choice in the termite hunting ant Megaponera analis.

    Science.gov (United States)

    Frank, Erik T; Hönle, Philipp O; Linsenmair, K Eduard

    2018-05-10

    Trail network systems among ants have received a lot of scientific attention due to their various applications in problem solving of networks. Recent studies have shown that ants select the fastest available path when facing different velocities on different substrates, rather than the shortest distance. The progress of decision-making by these ants is determined by pheromone-based maintenance of paths, which is a collective decision. However, path optimization through individual decision-making remains mostly unexplored. Here we present the first study of time-optimized path selection via individual decision-making by scout ants. Megaponera analis scouts search for termite foraging sites and lead highly organized raid columns to them. The path of the scout determines the path of the column. Through installation of artificial roads around M. analis nests we were able to influence the pathway choice of the raids. After road installation 59% of all recorded raids took place completely or partly on the road, instead of the direct, i.e. distance-optimized, path through grass from the nest to the termites. The raid velocity on the road was more than double the grass velocity, the detour thus saved 34.77±23.01% of the travel time compared to a hypothetical direct path. The pathway choice of the ants was similar to a mathematical model of least time allowing us to hypothesize the underlying mechanisms regulating the behavior. Our results highlight the importance of individual decision-making in the foraging behavior of ants and show a new procedure of pathway optimization. © 2018. Published by The Company of Biologists Ltd.

  19. Characteristics of transplacental lead transfer in rat dams and fetuses

    International Nuclear Information System (INIS)

    Kopfler, F.C.; Miller, R.G.; Kowal, N.E.; Kelty, K.C.; Doerger, J.U.; Mills, T.

    1987-01-01

    This study was designed to quantitate the dose resulting from lead exposure during the critical periods of brain development during gestation by determining: (1) if blood lead concentration in rat dams is affected by pregnancy status or duration of lead exposure, (2) if lead concentration in fetuses is associated with the duration of dam exposure, (3) the rates of lead absorption and elimination in pregnant and nonpregnant dams; and (4) the effect that prebreeding exposure on lead kinetics in the dam and upon fetus blood lead concentrations. The results of experiments in which the dams' drinking water contained 50 mg/L lead indicate blood lead levels (after normalizing by water consumption on a body weight basis) of pregnant rats are significantly higher than blood lead levels of non-pregnant rats. Statistical differences in blood lead levels were observed by day 15 of gestation and continue through day 20 of gestation. These blood lead differences are not due to lead treatment prior to breeding as seen when comparing Figure 1 and Figure 2. The blood lead levels of the fetuses at day 20 of gestation were 50-60% higher than that of the corresponding dams. The results from the latter two phases were ambiguous, due to large variability in individual animal absorption and elimination rates. However, the following observations can be made. Preexposure to lead does not affect the percent of lead transferred from the dams' blood to the fetuses. The rate of elimination of lead from the dams' blood does not appear to be affected by prebreeding exposure to lead or by the status of pregnancy. The fraction of the 203 Pb dose transferred to the fetus increases dramatically toward the end of gestation. The data suggest that lead absorption from the gut of pregnant rats is higher than that for nonpregnant rats

  20. Non-equilibrium Green's functions method: Non-trivial and disordered leads

    Energy Technology Data Exchange (ETDEWEB)

    He, Yu, E-mail: heyuyhe@gmail.com; Wang, Yu; Klimeck, Gerhard; Kubis, Tillmann [Network for Computational Nanotechnology, Purdue University, West Lafayette, Indiana 47907 (United States)

    2014-11-24

    The non-equilibrium Green's function algorithm requires contact self-energies to model charge injection and extraction. All existing approaches assume infinitely periodic leads attached to a possibly quite complex device. This contradicts today's realistic devices in which contacts are spatially inhomogeneous, chemically disordered, and impacting the overall device characteristics. This work extends the complex absorbing potentials method for arbitrary, ideal, or non-ideal leads in atomistic tight binding representation. The algorithm is demonstrated on a Si nanowire with periodic leads, a graphene nanoribbon with trumpet shape leads, and devices with leads of randomly alloyed Si{sub 0.5}Ge{sub 0.5}. It is found that alloy randomness in the leads can reduce the predicted ON-state current of Si{sub 0.5}Ge{sub 0.5} transistors by 45% compared to conventional lead methods.

  1. Broiler adaptation to post-hatching period

    Directory of Open Access Journals (Sweden)

    Maiorka Alex

    2006-01-01

    Full Text Available In the latest years more attention has been given to mechanisms for bird adaptation at post-hatching period by management of environmental conditions and formulations of diets offered during this period when digestive, immune, and thermo-regulating systems suffer slight changes. In post-hatching period, digestive system is anatomically complete, but its functionality is still immature in relation to adult birds. The chick immunity depends on maternal antibodies transferred to egg just before laying. In addition, variations within thermal comfort zone might affect initial development of chick. For example, high temperatures may induce hyperthermia with dehydration, while low temperatures may lead to hypothermia responsible by pulmonary hypertension syndrome. In conclusion, productivity might be enhanced when good conditions are offered to chicks during the period from last embryo development to first days after hatching.

  2. Lead in teeth from lead-dosed goats: Microdistribution and relationship to the cumulative lead dose

    International Nuclear Information System (INIS)

    Bellis, David J.; Hetter, Katherine M.; Jones, Joseph; Amarasiriwardena, Dula; Parsons, Patrick J.

    2008-01-01

    Teeth are commonly used as a biomarker of long-term lead exposure. There appear to be few data, however, on the content or distribution of lead in teeth where data on specific lead intake (dose) are also available. This study describes the analysis of a convenience sample of teeth from animals that were dosed with lead for other purposes, i.e., a proficiency testing program for blood lead. Lead concentration of whole teeth obtained from 23 animals, as determined by atomic absorption spectrometry, varied from 0.6 to 80 μg g -1 . Linear regression of whole tooth lead (μg g -1 ) on the cumulative lead dose received by the animal (g) yielded a slope of 1.2, with r 2 =0.647 (p -1 , were found in circumpulpal dentine. Linear regression of circumpulpal lead (μg g -1 ) on cumulative lead dose (g) yielded a slope of 23 with r 2 =0.961 (p=0.0001). The data indicated that whole tooth lead, and especially circumpulpal lead, of dosed goats increased linearly with cumulative lead exposure. These data suggest that circumpulpal dentine is a better biomarker of cumulative lead exposure than is whole tooth lead, at least for lead-dosed goats

  3. Multilevel Production Systems with Dependent Demand with Uncertainty of Lead Times

    Directory of Open Access Journals (Sweden)

    Haibatolah Sadeghi

    2016-01-01

    Full Text Available This study considers a multilevel assembly system with several components in each sublevel. It is assumed that actual lead time for all components is probabilistic; and periodic order quantity (POQ policy for ordering is utilized. If at a certain level a job is not received at the expected time, a delay is incurred at the delivery of production at this level and this may result in backorders of the finished product. It is assumed in this case that a fixed percentage of the shortage is backlogged and other sales are lost. In the real situation, some but not all customers will wait for backlogged components during a period of shortage, such as for fashionable commodities or high-tech products with the short product life cycle. The objective of this study is to find the planned lead time and periodicity for the total components in order to minimize the expected fixed ordering, holding, and partial backlogging costs for the finished product. In this study, it is assumed that a percentage of components at each level are scrap. A general mathematical model is suggested and the method developed can be used for optimization planned lead time and periodicity for such an MRP system under lead time uncertainties.

  4. Inflation from periodic extra dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Higaki, Tetsutaro [Department of Physics, Keio University, Kanagawa 223-8522 (Japan); Tatsuta, Yoshiyuki, E-mail: thigaki@rk.phys.keio.ac.jp, E-mail: y_tatsuta@akane.waseda.jp [Department of Physics, Waseda University, Tokyo 169-8555 (Japan)

    2017-07-01

    We discuss a realization of a small field inflation based on string inspired supergravities. In theories accompanying extra dimensions, compactification of them with small radii is required for realistic situations. Since the extra dimension can have a periodicity, there will appear (quasi-)periodic functions under transformations of moduli of the extra dimensions in low energy scales. Such a periodic property can lead to a UV completion of so-called multi-natural inflation model where inflaton potential consists of a sum of multiple sinusoidal functions with a decay constant smaller than the Planck scale. As an illustration, we construct a SUSY breaking model, and then show that such an inflaton potential can be generated by a sum of world sheet instantons in intersecting brane models on extra dimensions containing orbifold. We show also predictions of cosmic observables by numerical analyzes.

  5. PERSISTENCE IN PERFORMANCE FOR MUTUAL FUNDS IN PERIODS OF CRISIS

    Directory of Open Access Journals (Sweden)

    Theodoros KARGIDIS

    2012-09-01

    Full Text Available The study investigates the persistence in performance for a sample of South European funds, domiciled in Portugal, Italy, Greece and Spain. Employing the Sharpe ratio, risk adjusted performance is measured in an attempt to judge the influence of the 2008 crisis and the current debt crisis on funds’ inclination to persist in their previous returns record. Examination period extends from January 2004 to December 2010 incorporating stages of relative stability in the stock and bond markets while also capturing the early stages of the eurozone crisis. We categorize funds as winners and losers in consecutive 6-monthly periods, thus being able to judge persistence in the short run, while our results suggest that the identification of winners and losers could enable us to investigate the possibility to gain investment advantages through this finding. Overall results suggest evidence of persistent results, whether positive or negative, both during the 2008 crisis and the current debt crisis, leading us to deduce that factors leading to performance persistence are not affected by market changes, since medium to long term persistence bypasses any temporary market mischief. This finding could be of use for fund managers aiming at establishing viable investment strategies, at their epicenter being the exploitation of such clues, suggesting persistence in returns. A fund of funds manager employing funds both in equities and fixed income could potentially choose to invest exclusively or more heavily in the winners of previous periods and avoid accordingly poor performers, thus achieving higher returns on average. For this purpose simple investment strategies are employed where we test the outcome of an investment strategy that would invest on fixed income securities by choosing those funds that were winners in the distribution of returns in the previous 6-monthly period, while disinvesting from poor performers and funds switching sides in performance

  6. Lead exposure potentiates predatory attack behavior in the cat

    International Nuclear Information System (INIS)

    Li Wenjie; Han Shenggao; Gregg, T.R.; Kemp, F.W.Francis W.; Davidow, A.L.; Louria, D.B.; Siegel, Allan; Bogden, J.D.

    2003-01-01

    Epidemiologic studies have demonstrated that environmental lead exposure is associated with aggressive behavior in children; however, numerous confounding variables limit the ability of these studies to establish a causal relationship. The study of aggressive behavior using a validated animal model was used to test the hypothesis that there is a causal relationship between lead exposure and aggression in the absence of confounding variables. We studied the effects of lead exposure on a feline model of aggression: predatory (quiet biting) attack of an anesthetized rat. Five cats were stimulated with a precisely controlled electrical current via electrodes inserted into the lateral hypothalamus. The response measure was the predatory attack threshold current (i.e., the current required to elicit an attack response on 50% of the trials). Blocks of trials were administered in which predatory attack threshold currents were measured three times a week for a total of 6-10 weeks, including before, during, and after lead exposure. Lead was incorporated into cat food 'treats' at doses of 50-150 mg/kg/day. Two of the five cats received a second period of lead exposure. Blood lead concentrations were measured twice a week and were <1, 21-77, and <20 μg/dL prior to, during, and after lead exposure, respectively. The predatory attack threshold decreased significantly during initial lead exposure in three of five cats and increased after the cessation of lead exposure in four of the five cats (P<0.01). The predatory attack thresholds and blood lead concentrations for each cat were inversely correlated (r=-0.35 to -0.74). A random-effects mixed model demonstrated a significant (P=0.0019) negative association between threshold current and blood lead concentration. The data of this study demonstrate that lead exposure enhances predatory aggression in the cat and provide experimental support for a causal relationship between lead exposure and aggressive behavior in humans

  7. Adventures in Rocket Science. EG-2007-12-179-MSFC

    Science.gov (United States)

    Huegele, Vince; Hill, Kristy; Terry, Brenda

    2008-01-01

    This guide was prepared as a tool useful for informal education venues (4-H, Boys and Girls Clubs, Boy Scouts, Girl Scouts, etc.), science clubs and related programs, and can be adopted for formal education settings. An exciting and productive study in rocket science can be implemented using the selected activities for the above-mentioned…

  8. On the spin period distribution in Be/X-ray binaries

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Z.-Q.; Shao, Y.; Li, X.-D., E-mail: lixd@nju.edu.cn [Department of Astronomy, Nanjing University, Nanjing 210093 (China)

    2014-05-10

    There is a remarkable correlation between the spin periods of the accreting neutron stars (NSs) in Be/X-ray binaries (BeXBs) and their orbital periods. Recently, Knigge et al. showed that the distribution of the spin periods contains two distinct subpopulations peaked at ∼10 s and ∼200 s, respectively, and suggested that they may be related to two types of supernovae for the formation of the NSs, i.e., core-collapse and electron-capture supernovae. Here we propose that the bimodal spin period distribution is likely to be ascribed to different accretion modes of the NSs in BeXBs. When the NS tends to capture material from the warped, outer part of the Be star disk and experiences giant outbursts, a radiatively cooling dominated disk is formed around the NS, which spins up the NS and is responsible for the short-period subpopulation. In BeXBs that are dominated by normal outbursts or are persistent, the accretion flow is advection-dominated or quasi-spherical. The spin-up process is accordingly inefficient, leading to longer periods of the neuron stars. The potential relation between the subpopulations and the supernova mechanism is also discussed.

  9. Lead toxicity: current concerns.

    OpenAIRE

    Goyer, R A

    1993-01-01

    Over the 20-year period since the first issue of Environmental Health Perspectives was published, there has been considerable progress in the understanding of the potential toxicity of exposure to lead. Many of these advances have been reviewed in published symposia, conferences, and review papers in EHP. This brief review identifies major advances as well as a number of current concerns that present opportunities for prevention and intervention strategies. The major scientific advance has be...

  10. Behavior of lead and zinc in plasma, erythrocytes, and urine and ALAD in erythrocytes following intravenous infusion of CaEDTA in lead workers.

    Science.gov (United States)

    Araki, S; Aono, H; Fukahori, M; Tabuki, K

    1984-01-01

    To evaluate the effect of calcium disodium ethylenediamine tetraacetate (CaEDTA) on concentrations of lead and zinc in plasma, erythrocytes, whole blood, and urine, we administered CaEDTA by intravenous infusion for 1 hr to seven lead workers with blood lead concentrations of 46-67 micrograms/100 g (mean 54 micrograms/100 g). The plasma lead concentration (PPb) and the mobilization yield of lead in urine by CaEDTA were highest during the period between 1 and 2 hr after the infusion was started. In contrast, the lead concentration in erythrocytes (EPb) and in whole blood (BPb) remained unchanged during the 24 hr following infusion. Plasma zinc concentration (PZn) also fell rapidly following CaEDTA infusion; the decline was followed by a gradual rise in the zinc concentration in erythrocytes (EZn) without alteration in the zinc in whole blood. The mobilization yield of zinc in urine by CaEDTA (MZn) reached its highest level within 1 hr after the start of the infusion. Delta-aminolevulinic acid dehydratase (ALAD) activity in erythrocytes gradually increased for 5 hr following CaEDTA infusion. These observations suggest that (1) PPb concentration is a more sensitive indicator of the body burden of chelatable lead than is either BPb or EPb; (2) MZn is mobilized mostly from plasma during the first several hours following the start of CaEDTA infusion, and the fall in PZn concentration following infusion is compensated first by a rise in EZn concentration and then by an immediate redistribution of zinc in other organs to the blood; and (3) Pb-inhibited ALAD activity is reactivated by the increased EZn during and shortly after CaEDTA infusion.

  11. Numerical and Experimental Investigation of Stop-Bands in Finite and Infinite Periodic One-Dimensional Structures

    DEFF Research Database (Denmark)

    Domadiya, Parthkumar Gandalal; Manconi, Elisabetta; Vanali, Marcello

    2016-01-01

    Adding periodicity to structures leads to wavemode interaction, which generates pass- and stop-bands. The frequencies at which stop-bands occur are related to the periodic nature of the structure. Thus structural periodicity can be shaped in order to design vibro-acoustic filters for reducing...... method deals with the evaluation of a vibration level difference (VLD) in a finite periodic structure embedded within an infinite one-dimensional waveguide. This VLD is defined to predict the performance in terms of noise and vibration insulation of periodic cells embedded in an otherwise uniform...

  12. Influence of lead-doped hydroponic medium on the adsorption/bioaccumulation processes of lead and phosphorus in roots and leaves of the aquatic macrophyte Eicchornia crassipes.

    Science.gov (United States)

    Espinoza-Quiñones, Fernando R; Módenes, Aparecido Nivaldo; de Oliveira, Ana Paula; Trigueros, Daniela Estelita Goes

    2013-11-30

    In this study, lead bioaccumulation by the living free-floating aquatic macrophyte Eicchornia crassipes in different hydroponic conditions with variations in phosphorus and lead concentrations was investigated. A set of growth experiments in hydroponic media doped with lead and phosphorus within a wide concentration range was performed for 32 days in a greenhouse. All experiments were carried out with periodic replacement of all nutrients and lead. The concentration of lead and nutrients in biomass was determined by synchrotron radiation-excited total reflection X-ray fluorescence. By increasing the lead concentration in the medium, a reduction in biomass growth was observed, but a higher phosphorus retention in roots and leaves was shown at lower lead concentrations. In addition, an increase in the amount of bioaccumulated lead and phosphorus in roots was observed for higher lead and phosphorus concentrations in the medium, reaching saturation values of 4 mg Pb g(-1) and 7 mg P g(-1), respectively. Four non-structural kinetic models were tested, to represent the bioaccumulation of lead and phosphorus in roots. Pseudo-second order and irreversible kinetic models described the lead bioaccumulation data well, however, an irreversible kinetic model better fitted phosphorus uptake in roots. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. Lead levels in tissues and stomach contents of poisoned cattle: a fifteen-year survey

    Energy Technology Data Exchange (ETDEWEB)

    Hatch, R C; Funnell, H S

    1969-10-01

    During the period 1954 to 1969, samples of ingesta, liver, or kidney from 175 cattle which died of lead poisoning were analyzed for lead content. The average lead levels, and the extremes, were: ingesta, 3427 ppm (zero to 146,200 ppm); liver, 43 ppm (zero to 1300 ppm); and kidney, 137 ppm (two to 2355 ppm). There were no relationships between ingesta levels of lead and levels in the tissues tested. Taken with published results of natural and experimental lead poisoning in other cattle, the data indicate that the mere presence of lead in kidney (or liver) and ingesta should lead to a presumptive diagnosis of lead poisoning in cattle which die with signs, lesions, and histories characteristic of lead poisoning. Diagnosis may be confirmed by proof of access to, or ingestion of, a source of lead.

  14. Aging of residual surface resistance of superconducting lead cavities

    DEFF Research Database (Denmark)

    Danielsen, M.

    1972-01-01

    Measurements of the residual surface resistance of superconducting lead cavities as a function of time during a period of a month showed an oscillating variation. An explanation of the ageing curves is proposed. ©1972 The American Institute of Physics......Measurements of the residual surface resistance of superconducting lead cavities as a function of time during a period of a month showed an oscillating variation. An explanation of the ageing curves is proposed. ©1972 The American Institute of Physics...

  15. Mortality study of lead workers

    Energy Technology Data Exchange (ETDEWEB)

    Cooper, W C; Gaffey, W R

    1975-01-01

    The mortality of 7,032 men employed for one or more years in lead production facilities or battery plants was followed over a 23-year period, 1947-70. Lead absorption in many of these men was greatly in excess of currently accepted standards based upon urinary and blood lead concentrations available for a portion of the group. There were 1,356 deaths reported. The standardized mortality ratio (SMR) for all causes was 107 for smelter workers and 99 for battery plant workers. Death from neoplasms were in slight excess in smelters, but not significantly increased in battery plants. There were no excess deaths from kidney tumors. The SMR for cardiovascular-renal disease was 96 for smelter workers and 101 for battery plant workers. There was definitely no excess in deaths from either stroke or hypertensive heart disease; however, deaths classified as other hypertensive disease and unspecified nephritis or renal sclerosis were higher than expected. The life expectancy of lead workers was calculated to be approximately the same as that of all U.S. males.

  16. Effects of Lead+Selenium Interaction on Acetylcholinesterase Activity in Brain and Accumulation of Metal in Tissues of Oreochromis niloticus (L., 1758

    Directory of Open Access Journals (Sweden)

    Gülsemin Şen

    2017-06-01

    Full Text Available The potential accumulation of lead in different tissues of Oreochromis niloticus and the effects of selenium in AChE inhibition caused by lead in brain were investigated. Juvenile O. niloticus samples were exposed to combination of 1 mg L-1 and 2 mg L-1 lead and 1mg L-1 lead+2mg L-1 selenium and 2mg L-1 lead+4mg L-1 selenium for 1, 7 and 15 days respectively. The accumulation of lead in gill, brain, liver and muscle tissues was analyzed by Inductively Coupled Plasma Mass Spectrometry (ICP-MS as well as brain acetylcholinesterase (AChE, E.C.3.1.1.7 enzyme activity was also analyzed by spectrophotometric method. No mortality was observed during lead exposure in relation to time period and exposed concentrations. Lead accumulation was occurred in all tissues in relation to time. Maximum lead accumulation occurred in brain tissue, followed by the liver, gills and muscle tissues in relation to time period. Selenium caused decrease accumulation of lead in tissues (all selenium mixtures in muscle tissue on the first day, 1mg L-1 Pb+2mg L-1 selenium in gill tissue on the seventh day, in liver tissue on the seventh day except 2mg L-1 Pb+4mg L-1 selenium mixtures at the end of each of all three test periods. Inhibition of AChE activity was caused by the highest concentration and by the short-term effect of lead. Such effect of lead was eliminated by selenium mixture. Lead and selenium mixture were resulted an increase in activity on 15th day at the highest concentration. Selenium led to decrease in the accumulation of lead in the tissues and caused to improvement in the loss of AChE activity.

  17. Entrainment to periodic initiation and transition rates in a computational model for gene translation.

    Directory of Open Access Journals (Sweden)

    Michael Margaliot

    Full Text Available Periodic oscillations play an important role in many biomedical systems. Proper functioning of biological systems that respond to periodic signals requires the ability to synchronize with the periodic excitation. For example, the sleep/wake cycle is a manifestation of an internal timing system that synchronizes to the solar day. In the terminology of systems theory, the biological system must entrain or phase-lock to the periodic excitation. Entrainment is also important in synthetic biology. For example, connecting several artificial biological systems that entrain to a common clock may lead to a well-functioning modular system. The cell-cycle is a periodic program that regulates DNA synthesis and cell division. Recent biological studies suggest that cell-cycle related genes entrain to this periodic program at the gene translation level, leading to periodically-varying protein levels of these genes. The ribosome flow model (RFM is a deterministic model obtained via a mean-field approximation of a stochastic model from statistical physics that has been used to model numerous processes including ribosome flow along the mRNA. Here we analyze the RFM under the assumption that the initiation and/or transition rates vary periodically with a common period T. We show that the ribosome distribution profile in the RFM entrains to this periodic excitation. In particular, the protein synthesis pattern converges to a unique periodic solution with period T. To the best of our knowledge, this is the first proof of entrainment in a mathematical model for translation that encapsulates aspects such as initiation and termination rates, ribosomal movement and interactions, and non-homogeneous elongation speeds along the mRNA. Our results support the conjecture that periodic oscillations in tRNA levels and other factors related to the translation process can induce periodic oscillations in protein levels, and may suggest a new approach for re-engineering genetic

  18. Lead and zinc contamination of vegetation in the southern Pennines

    Energy Technology Data Exchange (ETDEWEB)

    Shimwell, D W; Laurie, A E

    1972-01-01

    Three types of heavy metal tolerant vegetation occurring on the spoil heaps in the Pennines are described sociologically and ecologically and their distribution in the Peak District National Park mapped. Concentrations of lead and zinc extractable from soils by acetic acid are recorded, as are total values for these two heavy metals in the tissues of the main component phanerogams and cryptogams of the vegetation. The range of values for zinc in plant tissues are uniformly higher than those for lead. Concentrations of lead accumulated by these plants are higher than those reported for the accumulation of atmospheric lead. The differences in heavy metal absorption, retention and excretion between ectohydric and myxohydric mosses are shown to be quite distinct. The heavy metals are excreted in the former type and form a crust in periods of drought with up to 6% lead and 1.5% zinc content, while, in the latter, the metals tend to be located mainly in the older growth at the base of the moss carpets. The concentrations of the two metal ions in two Peak District rivers proved to be less than 1 ppm in all samples.

  19. Relative importance of dissolved and food pathways for lead contamination in shrimp

    Energy Technology Data Exchange (ETDEWEB)

    Boisson, F.; Cotret, O.; Teyssie, J.-L.; El-Baradeie, M.; Fowler, S.W

    2003-12-01

    The relative importance of dissolved and food pathways and the influence of food type in the bioaccumulation and retention of lead in the shrimp Palaemonetes varians were examined using a radiotracer method. Shrimp were exposed to {sup 210}Pb-labelled seawater or fed two types of {sup 210}Pb-labelled food, viz. mussels or worms. The amount of radiotracer accumulated by shrimp was examined over a 7-day period, followed by a 1-month and a 7-day depuration period for the dissolved and food source, respectively. Steady state in the uptake was reached after 2 days exposure to dissolved lead, with a resultant estimated concentration factor of 98 {+-} 3. Transfer factors following ingestion of contaminated mussels and worms were lower than unity for both food types, with lead transfer from worms being significantly higher than that from mussels. Accumulation of dissolved Pb by shrimp was found to occur mainly through adsorption on the exoskeleton with a minor accumulation in the internal tissues probably resulting from the intake of seawater for osmoregulation. In contrast, lead taken up from contaminated food was readily absorbed and bound in the internal tissues of P. varians. Although the transfer of lead to P. varians through the ingestion of contaminated food was low (TF < 1%), it still represented 4 to 8% of the lead content in the prey which is a significant additional contribution of lead to the shrimp body burden. Independent of food type, following ingestion of contaminated food, approximately 23-27% of total lead accumulated in shrimp was located in the edible parts (e.g. muscle). Therefore, the food pathway is suggested to be a significant contributor to the lead transfer to humans through ingestion of contaminated shrimp. After exposure to contaminated food, lead loss kinetics were described by a two-component model, whereas Pb loss following direct uptake from seawater was best described by a three-component model. The additional compartment representing 64

  20. Relative importance of dissolved and food pathways for lead contamination in shrimp

    International Nuclear Information System (INIS)

    Boisson, F.; Cotret, O.; Teyssie, J.-L.; El-Baradeie, M.; Fowler, S.W.

    2003-01-01

    The relative importance of dissolved and food pathways and the influence of food type in the bioaccumulation and retention of lead in the shrimp Palaemonetes varians were examined using a radiotracer method. Shrimp were exposed to 210 Pb-labelled seawater or fed two types of 210 Pb-labelled food, viz. mussels or worms. The amount of radiotracer accumulated by shrimp was examined over a 7-day period, followed by a 1-month and a 7-day depuration period for the dissolved and food source, respectively. Steady state in the uptake was reached after 2 days exposure to dissolved lead, with a resultant estimated concentration factor of 98 ± 3. Transfer factors following ingestion of contaminated mussels and worms were lower than unity for both food types, with lead transfer from worms being significantly higher than that from mussels. Accumulation of dissolved Pb by shrimp was found to occur mainly through adsorption on the exoskeleton with a minor accumulation in the internal tissues probably resulting from the intake of seawater for osmoregulation. In contrast, lead taken up from contaminated food was readily absorbed and bound in the internal tissues of P. varians. Although the transfer of lead to P. varians through the ingestion of contaminated food was low (TF < 1%), it still represented 4 to 8% of the lead content in the prey which is a significant additional contribution of lead to the shrimp body burden. Independent of food type, following ingestion of contaminated food, approximately 23-27% of total lead accumulated in shrimp was located in the edible parts (e.g. muscle). Therefore, the food pathway is suggested to be a significant contributor to the lead transfer to humans through ingestion of contaminated shrimp. After exposure to contaminated food, lead loss kinetics were described by a two-component model, whereas Pb loss following direct uptake from seawater was best described by a three-component model. The additional compartment representing 64% of total Pb

  1. Current-driven plasmonic boom instability in three-dimensional gated periodic ballistic nanostructures

    Science.gov (United States)

    Aizin, G. R.; Mikalopas, J.; Shur, M.

    2016-05-01

    An alternative approach of using a distributed transmission line analogy for solving transport equations for ballistic nanostructures is applied for solving the three-dimensional problem of electron transport in gated ballistic nanostructures with periodically changing width. The structures with varying width allow for modulation of the electron drift velocity while keeping the plasma velocity constant. We predict that in such structures biased by a constant current, a periodic modulation of the electron drift velocity due to the varying width results in the instability of the plasma waves if the electron drift velocity to plasma wave velocity ratio changes from below to above unity. The physics of such instability is similar to that of the sonic boom, but, in the periodically modulated structures, this analog of the sonic boom is repeated many times leading to a larger increment of the instability. The constant plasma velocity in the sections of different width leads to resonant excitation of the unstable plasma modes with varying bias current. This effect (that we refer to as the superplasmonic boom condition) results in a strong enhancement of the instability. The predicted instability involves the oscillating dipole charge carried by the plasma waves. The plasmons can be efficiently coupled to the terahertz electromagnetic radiation due to the periodic geometry of the gated structure. Our estimates show that the analyzed instability should enable powerful tunable terahertz electronic sources.

  2. Petrol with isotopically differentiated lead added

    International Nuclear Information System (INIS)

    Magi, F.; Facchetti, S.; Garibaldi, P.

    1975-01-01

    An experiment is proposed aimed at determining the role of motor traffic in the pollution of the environment by lead, in particular of air, soil, vegetation, food and the human body. The technique of determining the isotopic composition of lead, used in the right way, should enable the whole problem to be solved. It is intended to add lead with a constant isotopic composition different from that of normally occuring lead, whether natural in origin or otherwise, to petrol in at least two regions of Italy. Analyses of lead samples taken from the principal mines have shown that Australian lead (Broken Hill Mine) has quite a different isotopic composition. This lead will therefore be used to prepare the antiknock additives for petrol sold in the regions in question. Adequate sampling should make it possible to determine the contribution to pollution of lead from motor vehicle exhausts. The regions chosen for the experiment are Piedmont (city and province of Turin) and Sardinia (city and province of Cagliari) - the first because of its high traffic density and level of industrialization, the second because of its remoteness and the lead content of the soil, which may affect food. Both regions present favourable conditions for supplying petrol of the intended type. The experiment is intended to last three years; the petrol with Australian lead will be marketed for a period of 18 months. The first results of analyses of the isotopic composition of lead contained in atmospheric dust in the city of Turin and of lead from a number of blood samples are reported in the paper

  3. Performance of the MFTF magnet cryogenic power leads

    International Nuclear Information System (INIS)

    VanSant, J.H.

    1983-01-01

    The cryogenic power lead system for the MFTF superconducting magnets has been acceptance tested and operated with the magnets. This system, which includes 5-m-long superconducting buses, 1.5-m-long vapor-cooled transition leads, external warm buses, and a cryostack, can conduct up to 6000 A (dc) and operate adiabatically for long periods. We present both design details and performance data; our MFTF version is an example of a reliable lead system for large superconducting magnets contained in a much larger vacuum vessel

  4. Inventory control in multi-echelon divergent systems with random lead times

    NARCIS (Netherlands)

    Heijden, van der M.C.; Diks, E.B.; Kok, de A.G.

    1996-01-01

    This paper deals with integral inventory control in multi-echelon divergent systems with stochastic lead times. The policy considered is an echelon stock, periodic review, order-up-to (R, S) policy. A computational method is derived to obtain the order-up-to level and the allocation fractions

  5. Inventory control in multi-echelon divergent systems with random lead times

    NARCIS (Netherlands)

    van der Heijden, Matthijs C.; Diks, Erik; de Kok, Ton

    1999-01-01

    This paper deals with integral inventory control in multi-echelon divergent systems with stochastic lead times. The policy considered is an echelon stock, periodic review, order-up-to (R, S) policy. A computational method is derived to obtain the order-up-to level and the allocation fractions

  6. A new technique of "midline anchoring" in spinal cord stimulation dramatically reduces lead migration.

    Science.gov (United States)

    Mironer, Y Eugene; Brown, Christopher; Satterthwaite, John R; Cohen, Mary; Tonder, Lisa M; Grumman, Steve

    2004-01-01

    Spinal cord stimulation (SCS) is a popular method of treatment of chronic pain. Unfortunately, migration of the lead continues to be a serious complication of this therapy. In an attempt to reduce lateral migration of the SCS lead, we performed a retrospective assessment of a new technique of percutaneous lead placement. This new method of "midline anchoring" of the lead using the plica mediana dorsalis was tested against conventional technique in a retrospective study involving 122 trials and 91 implants of SCS over a period of five years. The use of "midline anchoring" resulted in a decrease in lead migration from 23% to 6% after trial insertion and from 24% to 7% after implantation. We conclude that "midline anchoring" of the SCS lead is an effective method of preventing lead migration.

  7. Leadless Cardiac Pacemaker Implantation After Lead Extraction in Patients With Severe Device Infection.

    Science.gov (United States)

    Kypta, Alexander; Blessberger, Hermann; Kammler, Juergen; Lambert, Thomas; Lichtenauer, Michael; Brandstaetter, Walter; Gabriel, Michael; Steinwender, Clemens

    2016-09-01

    Conventional pacemaker therapy is limited by short- and long-term complications, most notably device infection. Transcatheter pacing systems (TPS) may be beneficial in this kind of patients as they eliminate the need for a device pocket and leads and thus may reduce the risk of re-infection. We assessed a novel procedure in 6 patients with severe device infection who were pacemaker dependent. After lead extraction a single chamber TPS was implanted into the right ventricle. Of the 6 patients who underwent lead extraction due to severe device infection at our institution, 3 were diagnosed with a pocket infection only, whereas the other 3 showed symptoms of both pocket and lead infection. Successful lead extraction and TPS implantation was accomplished in all patients. Four patients were bridged with a temporary pacemaker between 2 hours and 2 days after lead extraction, whereas 2 patients had the TPS implanted during the same procedure just before traditional pacemaker system removal. All patients stayed free of infection during the follow-up period of 12 weeks. An additional positron emission tomography scan was performed in each patient and indicated no signs of an infection around the TPS. Transcather pacemaker implantation was safe and feasible in 6 patients and did not result in re-infection even if implanted before removal of the infected pacemaker system within the same procedure. Therefore, implantation of a TPS may be an option for patients with severe device infection, especially in those with blocked venous access or who are pacemaker dependent. © 2016 Wiley Periodicals, Inc.

  8. Patterns of Change in Psychological Variables Leading up to Competition in Superior Versus Inferior Performers.

    Science.gov (United States)

    Boat, Ruth; Taylor, Ian M

    2015-06-01

    The study explored patterns of change in a number of potentially performance-related variables (i.e., fatigue, social support, self-efficacy, autonomous motivation, mental skills) during the lead-up to a competitive triathlon, and whether these patterns of change differed for relatively superior versus inferior performers. Forty-two triathletes completed an inventory measuring the study variables every other day during a 2-week period leading up to competition. Performance was assessed using participants' race time, and using a self-referenced relative score compared with personal best times. Multilevel growth curve analyses revealed significant differences in growth trajectories over the 2-week period in mental skills use, social support, and fatigue. The results provide novel insight into how athletes' fluctuating psychological state in the 2 weeks before competition may be crucial in determining performance.

  9. Australian atmospheric lead deposition reconstructed using lead concentrations and isotopic compositions of archival lichen and fungi

    International Nuclear Information System (INIS)

    Wu, Liqin; Taylor, Mark Patrick; Handley, Heather K.; Wu, Michael

    2016-01-01

    Lead concentrations and their isotopic compositions were measured in lichen genera Cladonia and Usnea and fungi genus Trametes from the Greater Sydney region (New South Wales, Australia) that had been collected and archived over the past 120 years. The median lead concentrations were elevated in lichens and fungi prior to the introduction of leaded petrol (Cladonia 12.5 mg/kg; Usnea 15.6 mg/kg; Trametes 1.85 mg/kg) corresponding to early industrial development. During the period of leaded petrol use in Australian automobiles from 1932 to 2002, total median lead concentrations rose: Cladonia 18.8 mg/kg; Usnea 21.5 mg/kg; Trametes 4.3 mg/kg. Following the cessation of leaded petrol use, median total lead concentrations decreased sharply in the 2000s: Cladonia 4.8 mg/kg; Usnea 1.7 mg/kg. The lichen and fungi isotopic compositions reveal a significant decrease in "2"0"6Pb/"2"0"7Pb ratios from the end of 19th century to the 1970s. The following decades were characterised by lower allowable levels of lead additive in fuel and the introduction of unleaded petrol in 1985. The environmental response to these regulatory changes was that lichen and fungi "2"0"6Pb/"2"0"7Pb ratios increased, particularly from 1995 onwards. Although the lead isotope ratios of lichens continued to increase in the 2000s they do not return to pre-leaded petrol values. This demonstrates that historic leaded petrol emissions, inter alia other sources, remain a persistent source of anthropogenic contamination in the Greater Sydney region. - Highlights: • Total lead and isotopic composition can be measured in historic lichen and fungi. • Historic lichen and fungi samples can distinguish polluted and unpolluted areas. • Former leaded petrol depositions remain a significant environmental contaminant. - Analysis of a 120-year record of lichens and fungi from the Greater Sydney basin reveal marked shifts in total lead concentrations and lead isotope ratios in response to geogenic inputs

  10. Model atmospheres with periodic shocks. [pulsations and mass loss in variable stars

    Science.gov (United States)

    Bowen, G. H.

    1989-01-01

    The pulsation of a long-period variable star generates shock waves which dramatically affect the structure of the star's atmosphere and produce conditions that lead to rapid mass loss. Numerical modeling of atmospheres with periodic shocks is being pursued to study the processes involved and the evolutionary consequences for the stars. It is characteristic of these complex dynamical systems that most effects result from the interaction of various time-dependent processes.

  11. Low-level environmental lead exposure in childhood and adult intellectual function: a follow-up study

    Directory of Open Access Journals (Sweden)

    Gregas Matthew

    2011-03-01

    Full Text Available Abstract Background Early life lead exposure might be a risk factor for neurocognitive impairment in adulthood. Objectives We sought to assess the relationship between early life environmental lead exposure and intellectual function in adulthood. We also attempted to identify which time period blood-lead concentrations are most predictive of adult outcome. Methods We recruited adults in the Boston area who had participated as newborns and young children in a prospective cohort study that examined the relationship between lead exposure and childhood intellectual function. IQ was measured using the Wechsler Abbreviated Scale of Intelligence (WASI. The association between lead concentrations and IQ scores was examined using linear regression. Results Forty-three adults participated in neuropsychological testing. Childhood blood-lead concentration (mean of the blood-lead concentrations at ages 4 and 10 years had the strongest relationship with Full-Scale IQ (β = -1.89 ± 0.70, p = 0.01. Full-scale IQ was also significantly related to blood-lead concentration at age 6 months (β = -1.66 ± 0.75, p = 0.03, 4 years (β = -0.90 ± 0.41, p = 0.03 and 10 years (β = -1.95 ± 0.80, p = 0.02. Adjusting for maternal IQ altered the significance of the regression coefficient. Conclusions Our study suggests that lead exposure in childhood predicts intellectual functioning in young adulthood. Our results also suggest that school-age lead exposure may represent a period of increased susceptibility. Given the small sample size, however, the potentially confounding effects of maternal IQ cannot be excluded and should be evaluated in a larger study.

  12. Spatial and temporal variation in lead and cadmium in the Laughing Gull, Larus atricilla

    Energy Technology Data Exchange (ETDEWEB)

    Reid, M; Hacker, C S

    1982-11-01

    Lead and cadmium concentrations were measured in eggs and in bone, kidney, liver and stomach contents of downy young, prefledgling, and adult Laughing Gulls collected from Matagorda Bay and Galveston Bay, Texas. Matagorda Bay drains a rural, moderately industrialized region while the Galveston Bay area is heavily urbanized and industrialized. Lead levels were lower in birds from Matagorda Bay and decreased in birds from Galveston Bay between 1977 and 1980. Cadmium levels were also lower in birds from Matagorda Bay but increased over the three-year period in those from Galveston Bay. The temporal decrease in lead may be associated with such environmental control efforts as reduced point source emissions and substitution of unleaded gasoline.

  13. Assessment of the bacterial organisms in water from a lead-zinc ...

    African Journals Online (AJOL)

    Twenty-four (24) bulk water samples collected from a lead-zinc mining pit in Ishiagu, Ebonyi State, Nigeria over a period of 2 years were used to assess the bacterial population of the mining pit water. Nine bacterial organisms, which included Bacillus sp., Pseudomonas aeruginosa, Proteus sp., Escherichia coli, ...

  14. Inheritance of Cell-Cycle Duration in the Presence of Periodic Forcing

    Science.gov (United States)

    Mosheiff, Noga; Martins, Bruno M. C.; Pearl-Mizrahi, Sivan; Grünberger, Alexander; Helfrich, Stefan; Mihalcescu, Irina; Kohlheyer, Dietrich; Locke, James C. W.; Glass, Leon; Balaban, Nathalie Q.

    2018-04-01

    Periodic forcing of nonlinear oscillators leads to a large number of dynamic behaviors. The coupling of the cell cycle to the circadian clock provides a biological realization of such forcing. A previous model of forcing leads to nontrivial relations between correlations along cell lineages. Here, we present a simplified two-dimensional nonlinear map for the periodic forcing of the cell cycle. Using high-throughput single-cell microscopy, we have studied the correlations between cell-cycle duration in discrete lineages of several different organisms, including those with known coupling to a circadian clock and those without known coupling to a circadian clock. The model reproduces the paradoxical correlations and predicts new features that can be compared with the experimental data. By fitting the model to the data, we extract the important parameters that govern the dynamics. Interestingly, the model reproduces bimodal distributions for cell-cycle duration, as well as the gating of cell division by the phase of the clock, without having been explicitly fed into the model. In addition, the model predicts that circadian coupling may increase cell-to-cell variability in a clonal population of cells. In agreement with this prediction, deletion of the circadian clock reduces variability. Our results show that simple correlations can identify systems under periodic forcing and that studies of nonlinear coupling of biological oscillators provide insight into basic cellular processes of growth.

  15. Lead absorption in sheep fed forage contaminated with motor vehicle exhaust gases

    Energy Technology Data Exchange (ETDEWEB)

    Zuber, R; Bovay, E; Luginbuehl, H R; Loenig, H

    1972-01-01

    For a period of 24 weeks three sheep received hay contaminated with lead deposits from motor vehicle exhaust gases. The aim of this study was to compare the lead accumulation in different organs and tissues of two young sheep (I and II) consuming every day forage containing 8 and 73 ppM lead respectively (= milligrams per kg of dried substance). A third animal (III) was fed with forage containing 73 ppM Pb and received in addition water with 200 mg Pb/liter. The analyses made after slaughtering of the animals revealed a marked accumulation of lead in the liver, the bones of the pelvis, the kidneys, and the spleen. However, a notable proportion of lead is also excreted with the urine and feces. Histological studies revealed some changes in the hepatocytes of animals II and III. These lesions were more significant in animal III, which received the highest level of lead, than in animal II. It is possible that these alterations have been caused by toxic substances.

  16. Aerosols in the tropical and subtropical UT/LS: in-situ measurements of submicron particle abundance and volatility

    Directory of Open Access Journals (Sweden)

    S. Borrmann

    2010-06-01

    Full Text Available Processes occurring in the tropical upper troposphere (UT, the Tropical Transition Layer (TTL, and the lower stratosphere (LS are of importance for the global climate, for stratospheric dynamics and air chemistry, and for their influence on the global distribution of water vapour, trace gases and aerosols. In this contribution we present aerosol and trace gas (in-situ measurements from the tropical UT/LS over Southern Brazil, Northern Australia, and West Africa. The instruments were operated on board of the Russian high altitude research aircraft M-55 "Geophysica" and the DLR Falcon-20 during the campaigns TROCCINOX (Araçatuba, Brazil, February 2005, SCOUT-O3 (Darwin, Australia, December 2005, and SCOUT-AMMA (Ouagadougou, Burkina Faso, August 2006. The data cover submicron particle number densities and volatility from the COndensation PArticle counting System (COPAS, as well as relevant trace gases like N2O, ozone, and CO. We use these trace gas measurements to place the aerosol data into a broader atmospheric context. Also a juxtaposition of the submicron particle data with previous measurements over Costa Rica and other tropical locations between 1999 and 2007 (NASA DC-8 and NASA WB-57F is provided. The submicron particle number densities, as a function of altitude, were found to be remarkably constant in the tropical UT/LS altitude band for the two decades after 1987. Thus, a parameterisation suitable for models can be extracted from these measurements. Compared to the average levels in the period between 1987 and 2007 a slight increase of particle abundances was found for 2005/2006 at altitudes with potential temperatures, Θ, above 430 K. The origins of this increase are unknown except for increases measured during SCOUT-AMMA. Here the eruption of the Soufrière Hills volcano in the Caribbean caused elevated particle mixing ratios. The vertical profiles from Northern hemispheric mid-latitudes between 1999 and 2006 also are

  17. Tunable band gaps in bio-inspired periodic composites with nacre-like microstructure

    Science.gov (United States)

    Chen, Yanyu; Wang, Lifeng

    2014-08-01

    Periodic composite materials have many promising applications due to their unique ability to control the propagation of waves. Here, we report the existence and frequency tunability of complete elastic wave band gaps in bio-inspired periodic composites with nacre-like, brick-and-mortar microstructure. Numerical results show that complete band gaps in these periodic composites derive from local resonances or Bragg scattering, depending on the lattice angle and the volume fraction of each phase in the composites. The investigation of elastic wave propagation in finite periodic composites validates the simulated complete band gaps and further reveals the mechanisms leading to complete band gaps. Moreover, our results indicate that the topological arrangement of the mineral platelets and changes of material properties can be utilized to tune the evolution of complete band gaps. Our finding provides new opportunities to design mechanically robust periodic composite materials for wave absorption under hostile environments, such as for deep water applications.

  18. Tracer measurements in the tropical tropopause layer during the AMMA/SCOUT-O3 aircraft campaign

    Directory of Open Access Journals (Sweden)

    C. D. Homan

    2010-04-01

    Full Text Available We present airborne in situ measurements made during the AMMA (African Monsoon Multidisciplinary Analysis/SCOUT-O3 campaign between 31 July and 17 August 2006 on board the M55 Geophysica aircraft, based in Ouagadougou, Burkina Faso. CO2 and N2O were measured with the High Altitude Gas Analyzer (HAGAR, CO was measured with the Cryogenically Operated Laser Diode (COLD instrument, and O3 with the Fast Ozone ANalyzer (FOZAN.

    We analyse the data obtained during five local flights to study the dominant transport processes controlling the tropical tropopause layer (TTL, here ~350–375 K and lower stratosphere above West-Africa: deep convection up to the level of main convective outflow, overshooting of deep convection, and horizontal inmixing across the subtropical tropopause. Besides, we examine the morphology of the stratospheric subtropical barrier.

    Except for the flight of 13 August, distinct minima in CO2 mixing ratios indicate convective outflow of boundary layer air in the TTL. The CO2 profiles show that the level of main convective outflow was mostly located at potential temperatures between 350 and 360 K, and for 11 August reached up to 370 K.

    While the CO2 minima indicate quite significant convective influence, the O3 profiles suggest that the observed convective signatures were mostly not fresh, but of older origin (several days or more. When compared with the mean O3 profile measured during a previous campaign over Darwin in November 2005, the O3 minimum at the main convective outflow level was less pronounced over Ouagadougou. Furthermore O3 mixing ratios were much higher throughout the whole TTL and, unlike over Darwin, rarely showed low values observed in the regional boundary layer.

    Signatures of irreversible mixing following overshooting of convective air were scarce in the tracer data. Some

  19. Secular trend of the leading causes of death in China from 2003 to ...

    African Journals Online (AJOL)

    Secular trend of the leading causes of death in China from 2003 to 2013. ... African Health Sciences ... respiratory, and digestive system diseases in urban areas and genito-urinary system diseases in rural areas decreased during this period ...

  20. [Analysis of fatigue associated to periodic limb movement during sleep in former poliomyelitis patients].

    Science.gov (United States)

    Oliveira, A R; Correa, F I; Correa, J C F; Oliveira, L V F

    2012-01-01

    Following poliomyelitis, patients may experience sleep disorders stemming from periodic limb movement, leading to fatigue and compromised muscle function the following day. To establish the presence or absence of muscle fatigue in these patients using electromyography and relating the data to polysomnographic findings. An analytical cross-sectional study was carried out involving 19 individuals with motor sequelae in the lower limbs stemming from poliomyelitis. Quantitative tests for the assessment of neurophysiological aspects (knee-jerk/Achilles reflexes and peripheral muscle strength of rectus femoris) and a sleep study (standard, level I polysomnography) were administered. A statistically significant difference was detected (p fatigue associated to sleep disorder. Individuals with sequelae from poliomyelitis exhibit sleep disorders that may lead to muscle fatigue. Periodic limb movement may contribute to this phenomenon.

  1. Magnetic flux periodicities and finite momentum pairing in unconventional superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Loder, Florian

    2009-12-22

    This work contains a thorough study of the magnetic flux periodicity of loops of conventional and unconventional, especially d-wave, superconductors. Although already in 1961, several independent works showed that the flux period of a conventional superconducting loop is the superconducting flux quantum hc/2e, this question has never been investigated deeply for unconventional superconductors. And indeed, we show here that d-wave superconducting loops show a basic flux period of the normal flux quantum hc/e, a property originating from the nodal quasi-particle states. This doubling of the flux periodicity is best visible in the persistent current circulating in the loop, and it affects other properties of the superconductor such as the periodicity of d-wave Josephson junctions. In the second part of this work, the theory of electron pairing with finite center-of-mass momentum, necessary for the description of superconducting loops, is extended to systems in zero magnetic field. We show that even in the field free case, an unconventional pairing symmetry can lead to a superconducting ground state with finite-momentum electron pairs. Such a state has an inhomogeneous charge density and therefore is a basis for the description of coexistence of superconductivity and stripe order. (orig.)

  2. Model of tunnelling through periodic array of quantum dots

    Directory of Open Access Journals (Sweden)

    Meynster Dmitry

    2017-01-01

    Full Text Available Several explicitly solvable models of electron tunnelling in a system of single and double two-dimensional periodic arrays of quantum dots with two laterally coupled leads in a homogeneous magnetic field are constructed. First, a model of single layer formed by periodic array of zero-range potentials is described. The Landau operator (the Schrodinger operator with a magnetic field with point-like interactions is the system Hamiltonian. We deal with two types of the layer lattices: square and honeycomb. The periodicity condition gives one an invariance property for the Hamiltonian in respect to magnetic translations group. The consideration of double quantum layer reduces to the replacement of the basic cell for the single layer by a cell including centers of different layers. Two variants of themodel for the double layer are suggested: with direct tunneling between the layers and with the connecting channels (segments in the model between the layers. The theory of self-adjoint extensions of symmetric operators is a mathematical background of the model. The third stage of the construction is the description of leads connection. It is made by the operator extensions theory method too. Electron tunneling from input lead to the output lead through the double quantum layer is described. Energy ranges with extremely small (practically, zero transmission were found. Dependencies of the transmission coefficient (particularly, “zero transmission bands” positions on the magnetic field, the energy of electron and the distance between layers are investigated. The results are compared with the corresponding single-layer transmission.

  3. Lead in the environment

    Science.gov (United States)

    Pattee, Oliver H.; Pain, Deborah J.; Hoffman, David J.; Rattner, Barnett A.; Burton, G. Allen; Cairns, John

    2003-01-01

    Anthropogenic uses of lead have probably altered its availability and environmental distribution more than any other toxic element. Consequently, lead concentrations in many living organisms may be approaching thresholds of toxicity for the adverse effects of lead. Such thresholds are difficult to define, as they vary with the chemical and physical form of lead, exposure regime, other elements present and also vary both within and between species. The technological capability to accurately quantify low lead concentrations has increased over the last decade, and physiological and behavioral effects have been measured in wildlife with tissue lead concentrations below those previously considered safe for humans.s.236 Consequently. lead criteria for the protection of wildlife and human health are frequently under review, and 'thresholds' of lead toxicity are being reconsidered. Proposed lead criteria for the protection of natural resources have been reviewed by Eisler. Uptake of lead by plants is limited by its generally low availability in soils and sediments, and toxicity may be limited by storage mechanisms and its apparently limited translocation within most plants. Lead does not generally accumulate within the foliar parts of plants, which limits its transfer to higher trophic levels. Although lead may concentrate in plant and animal tissues, no evidence of biomagnification exists. Acid deposition onto surface waters and soils with low buffering capacity may influence the availability of lead for uptake by plants and animals, and this may merit investigation at susceptible sites. The biological significance of chronic low-level lead exposure to wildlife is sometimes difficult to quantify. Animals living in urban environments or near point sources of lead emission are inevitably subject to greater exposure to lead and enhanced risk of lead poisoning. Increasingly strict controls on lead emissions in many countries have reduced exposure to lead from some sources

  4. Photolysis of Periodate and Periodic Acid in Aqueous Solution

    DEFF Research Database (Denmark)

    Sehested, Knud; Kläning, U. K.

    1978-01-01

    The photochemistry of periodate and periodic acid in aqueous solution was studied (i) by quantum yield measurements at low light intensity (ii) by flash photolysis, and (iii) by photolysis of glassy samples at 77 K. The photochemical studies were supplemented with pulse radiolysis studies...... of aqueous periodate solutions and with kinetic studies using stopped-flow technique. In strongly alkaline solution the photodecomposition of periodate proceeds via formation of O– and IVI. At pH solution O3 P is formed in a small...

  5. Flow characterization in periodic microchannels containing asymmetric grooves

    Energy Technology Data Exchange (ETDEWEB)

    Osorio-Nesme, A; Delgado, A, E-mail: anuhar.nesme@fau.de [Institute of Fluid Mechanics, Friedrich-Alexander Erlangen-Nuremberg University, Cauerstrasse 4, D-91058 Erlangen (Germany)

    2017-10-15

    Characterization of two-dimensional flows in microchannels with anisotropic periodic grooves is numerically carried out by using the lattice Boltzmann method. Periodically placed microstructures, consisting of novel nozzle-diffuser-like grooves are deliberately designed to introduce a flow-direction dependent resistance. Simulations were conducted for a low-to-moderate Reynolds number in the laminar-transition flow regime. Different channel geometries, defined by the half-angle ϕ of the periodic grooves are considered. The influence of the half-angle on both the flow field and the onset of oscillatory flow regime at different driving body forces is analyzed. At a low Reynolds number, the flow is observed stationary and fully reversible, regardless of the groove geometry. In this regime, higher Reynolds numbers were observed when the geometry acts as a diffuser (negative flow) than as a nozzle (positive flow) for a given driving body force. At sufficiently high Reynolds number the flow turns from a steady state to a time-dependent oscillatory regime through a Hopf bifurcation. Successive flow bifurcations lead the flow structure from a periodic regime to a quasi-chaotic regime with three-dimensional structures. The onset of unsteady flow occurs earlier for positive flows and geometries with small half-angles. For higher driving forces, there is a reduction in the volume flow rate due to the advected material in the transversal direction, causing consequently a decrease in the Reynolds number. (paper)

  6. Concept of quasi-periodic undulator - control of radiation spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Sasaki, Shigemi [Japan Atomic Energy Research Institute, Ibaraki (Japan)

    1995-02-01

    A new type of undulator, the quasi-periodic undulator (QPU) is considered which generates the irrational harmonics in the radiation spectrum. This undulator consists of the arrays of magnet blocks aligned in a quasi-periodic order, and consequentially lead to a quasi-periodic motion of electron. A combination of the QPU and a conventional crystal/grating monochromator provides pure monochromatic photon beam for synchrotron radiation users because the irrational harmonics do not be diffracted in the same direction by a monochromator. The radiation power and width of each radiation peak emitted from this undulator are expected to be comparable with those of the conventional periodic undulator.

  7. 78 FR 10265 - Pricing for the 2013 Commemorative Coin Programs-Silver and Clad Coin Options

    Science.gov (United States)

    2013-02-13

    .... SUMMARY: The United States Mint is announcing prices for the 2013 Girl Scouts of the USA Centennial Silver.... Introductory Product price Regular price 2013 Girl Scouts of the USA Centennial $54.95 $59.95 Proof Silver Dollar 2013 Girl Scouts of the USA Centennial 50.95 55.95 Uncirculated Silver Dollar 2013 5-Star Generals...

  8. Redistribution of phase fluctuations in a periodically driven cuprate superconductor

    Energy Technology Data Exchange (ETDEWEB)

    Hoeppner, Robert; Zhu, Beilei; Rexin, Tobias [Zentrum fuer Optische Quantentechnologien und Institut fuer Laserphysik, Hamburg (Germany); Mathey, Ludwig [Zentrum fuer Optische Quantentechnologien und Institut fuer Laserphysik, Hamburg (Germany); The Hamburg Centre for Ultrafast Imaging, Hamburg (Germany); Cavalleri, Andrea [Max Planck Institute for the Structure and Dynamics of Matter, Hamburg (Germany); Department of Physics, Oxford University, Clarendon Laboratory, Parks Road, Oxford (United Kingdom)

    2015-07-01

    We study the thermally fluctuating state of a bi-layer cuprate superconductor under the periodic action of a staggered field oscillating at optical frequencies. This analysis distills essential elements of the recently discovered phenomenon of light enhanced coherence in YBCO, which was achieved by periodically driving infrared active apical oxygen distortions. The effect of a staggered periodic perturbation is studied using a Langevin description of driven, coupled Josephson junctions, which represent two neighboring pairs of layers and their two plasmons. We demonstrate that the external driving leads to a suppression of phase fluctuations of the low-energy plasmon, an effect which is amplified via the resonance of the high energy plasmon, with a striking suppression of the low-energy fluctuations, as visible in the power spectrum. We also find that this effect acts onto the in-plane fluctuations, which are reduced on long length scales and we discuss the behavior of vortices in the ab-planes and across the weakly coupled junctions.

  9. Anemia risk in relation to lead exposure in lead-related manufacturing

    Directory of Open Access Journals (Sweden)

    Nan-Hung Hsieh

    2017-05-01

    Full Text Available Abstract Background Lead-exposed workers may suffer adverse health effects under the currently regulated blood lead (BPb levels. However, a probabilistic assessment about lead exposure-associated anemia risk is lacking. The goal of this study was to examine the association between lead exposure and anemia risk among factory workers in Taiwan. Methods We first collated BPb and indicators of hematopoietic function data via health examination records that included 533 male and 218 female lead-exposed workers between 2012 and 2014. We used benchmark dose (BMD modeling to estimate the critical effect doses for detection of abnormal indicators. A risk-based probabilistic model was used to characterize the potential hazard of lead poisoning for job-specific workers by hazard index (HI. We applied Bayesian decision analysis to determine whether BMD could be implicated as a suitable BPb standard. Results Our results indicated that HI for total lead-exposed workers was 0.78 (95% confidence interval: 0.50–1.26 with risk occurrence probability of 11.1%. The abnormal risk of anemia indicators for male and female workers could be reduced, respectively, by 67–77% and 86–95% by adopting the suggested BPb standards of 25 and 15 μg/dL. Conclusions We conclude that cumulative exposure to lead in the workplace was significantly associated with anemia risk. This study suggests that current BPb standard needs to be better understood for the application of lead-exposed population protection in different scenarios to provide a novel standard for health management. Low-level lead exposure risk is an occupational and public health problem that should be paid more attention.

  10. Holocene elemental, lead isotope and charcoal record from peat in southern Poland

    Directory of Open Access Journals (Sweden)

    K. Tudyka

    2017-03-01

    Full Text Available This article presents a mid-resolution elemental, isotopic and charcoal record from 10700 BC to AD 500 in a peat core located in Żyglin (southern Poland. The objective is to give insight into the proxies with emphasis on lead (Pb sources in this minerogenic peat deposit. During the Early Holocene (10700–7550 BC the average 206Pb/207Pb quotient was around 1.196. This isotopic signature is consistent with natural dust derived from long-distance soil and rock weathering. The Mid-Holocene period (7550–3200 BC shows a significant change in the peat accumulation conditions. The growth rate is approximately 0.04 mm yr-1 and the 206Pb/207Pb quotients are shifted toward values that are found in local galena ores. This is simultaneous with a significantly increased lead flux which further confirms local sources of material in this peat deposit. In the Late Holocene period (3200 BC–AD 500 a large quantity of charcoal particles with diameters ranging from 2 mm up to 3 cm is found; also, Pb, Zn and Cu fluxes reach their highest values. This period corresponds to the Eneolithic, Bronze and Iron Ages, and human impact is recorded as charcoal.

  11. Pathobiological and Behavioral Effects of Lead Intoxication in the Infant Rhesus Monkey

    Science.gov (United States)

    Allen, J. R.; McWey, P. J.; Suomi, S. J.

    1974-01-01

    When infant rhesus monkeys were exposed to lead via the addition of lead acetate (0.5–9 mg/kg body weight) to their formula or by the consumption of lead particles from lead-based surrogate mothers, they developed symptoms of lead intoxication within 6 weeks. Seizures, muscular tremors, and altered social interaction were the predominant changes. Visual impairment was also apparent in the more severely affected animals. In the animals showing obvious symptoms lead levels varied between 300 to 500 μg/100 ml of blood. Even in those animals having blood lead levels below 100 μg, hyperactivity and insomnia were observed. When the exposure to lead was eliminated, seizures subsided and visual impairment was reduced; however, the abnormal social interaction persisted. These animals also experienced a gradual decline in hematocrit and hemoglobin values during the period of examination. Liver and kidney biopsies obtained from these lead-exposed animals revealed characteristic intranuclear inclusions. When adolescent and adult monkeys were exposed to doses of lead acetate similar to those employed in the infant experiments, lead levels in excess of 200 μg/100 ml of blood were recorded. However, there were no obvious behavioral abnormalities observed. There were, however, numerous lead inclusion bodies in kidney biopsy specimens from these animals. These data suggest that, like man, the infant nonhuman primate is much more susceptible to lead intoxication than is the adult. The clinical and behavioral changes recorded in these infant rhesus monkeys suggest their use as an experimental model to evaluate lead intoxication. ImagesFIGURE 6. PMID:4208658

  12. Localized accumulation of lead within and among bones from lead-dosed goats

    International Nuclear Information System (INIS)

    Cretacci, Yan; Parsons, Patrick J.

    2010-01-01

    The principal aim of this study was to gain a better understanding of where lead (Pb) accumulates and how it is distributed, within the bones of dosed goats. Adult goats were periodically dosed with Pb over a number of years for the primary purpose of producing blood pools containing endogenously bound Pb, for the New York State Blood Lead Proficiency Testing Program. Bone samples (e.g., primarily tibia, femur, humerus, and radius) were collected post-mortem from 11 animals and were analyzed for Pb content by acid digestion and electrothermal atomic absorption spectrometry (ETAAS or GFAAS). Average tibia Pb levels were found to correlate strongly with the cumulative Pb dose (r 2 =0.81). However, the concentration of Pb in different bones and even within a small area of the same bone varied tremendously. Blood-rich trabecular (spongy) bone, such as the patella and calcaneus, were much more enriched in Pb than was cortical (compact) bone. In some dosed animals, the Pb concentration in the tibia was markedly higher at the proximal and distal ends of the bone compared to the mid-shaft. The implications of these findings with regard to the noninvasive measurement of lead in bone by XRF methods are discussed.

  13. Localized accumulation of lead within and among bones from lead-dosed goats

    Energy Technology Data Exchange (ETDEWEB)

    Cretacci, Yan [Laboratory of Inorganic and Nuclear Chemistry, Wadsworth Center, New York State Department of Health, P.O. Box 509, Albany, NY 12201-0509 (United States); Department of Environmental Health Sciences, School of Public Health, The University at Albany, P.O. Box 509, Albany, NY 12201-0509 (United States); Parsons, Patrick J., E-mail: pparsons@wadsworth.org [Laboratory of Inorganic and Nuclear Chemistry, Wadsworth Center, New York State Department of Health, P.O. Box 509, Albany, NY 12201-0509 (United States); Department of Environmental Health Sciences, School of Public Health, The University at Albany, P.O. Box 509, Albany, NY 12201-0509 (United States)

    2010-01-15

    The principal aim of this study was to gain a better understanding of where lead (Pb) accumulates and how it is distributed, within the bones of dosed goats. Adult goats were periodically dosed with Pb over a number of years for the primary purpose of producing blood pools containing endogenously bound Pb, for the New York State Blood Lead Proficiency Testing Program. Bone samples (e.g., primarily tibia, femur, humerus, and radius) were collected post-mortem from 11 animals and were analyzed for Pb content by acid digestion and electrothermal atomic absorption spectrometry (ETAAS or GFAAS). Average tibia Pb levels were found to correlate strongly with the cumulative Pb dose (r{sup 2}=0.81). However, the concentration of Pb in different bones and even within a small area of the same bone varied tremendously. Blood-rich trabecular (spongy) bone, such as the patella and calcaneus, were much more enriched in Pb than was cortical (compact) bone. In some dosed animals, the Pb concentration in the tibia was markedly higher at the proximal and distal ends of the bone compared to the mid-shaft. The implications of these findings with regard to the noninvasive measurement of lead in bone by XRF methods are discussed.

  14. Melatonin reduces lead levels in blood, brain and bone and increases lead excretion in rats subjected to subacute lead treatment.

    Science.gov (United States)

    Hernández-Plata, Everardo; Quiroz-Compeán, Fátima; Ramírez-Garcia, Gonzalo; Barrientos, Eunice Yáñez; Rodríguez-Morales, Nadia M; Flores, Alberto; Wrobel, Katarzina; Wrobel, Kazimierz; Méndez, Isabel; Díaz-Muñoz, Mauricio; Robles, Juvencio; Martínez-Alfaro, Minerva

    2015-03-04

    Melatonin, a hormone known for its effects on free radical scavenging and antioxidant activity, can reduce lead toxicity in vivo and in vitro.We examined the effects of melatonin on lead bio-distribution. Rats were intraperitoneally injected with lead acetate (10, 15 or 20mg/kg/day) with or without melatonin (10mg/kg/day) daily for 10 days. In rats intoxicated with the highest lead doses, those treated with melatonin had lower lead levels in blood and higher levels in urine and feces than those treated with lead alone, suggesting that melatonin increases lead excretion. To explore the mechanism underlying this effect, we first assessed whether lead/melatonin complexes were formed directly. Electronic density functional (DFT) calculations showed that a lead/melatonin complex is energetically feasible; however, UV spectroscopy and NMR analysis showed no evidence of such complexes. Next, we examined the liver mRNA levels of metallothioneins (MT) 1 and 2. Melatonin cotreatment increased the MT2 mRNA expression in the liver of rats that received the highest doses of lead. The potential effects of MTs on the tissue distribution and excretion of lead are not well understood. This is the first report to suggest that melatonin directly affects lead levels in organisms exposed to subacute lead intoxication. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  15. Lead poisoning after gunshot wound

    Directory of Open Access Journals (Sweden)

    Paulo Roberto de Madureira

    2000-05-01

    Full Text Available CONTEXT: Despite the absence of symptoms in the majority of patients carrying lead bullet fragments in their bodies, there needs to be an awareness of the possible signs and symptoms of lead intoxication when bullets are lodged in large joints like knees, hips and shoulders. Such patients merit closer follow-up, and even surgical procedure for removing the fragments. OBJECTIVE: To describe a patient who developed clinical lead intoxication several years after a gunshot wound. DESIGN: Case report. CASE REPORT: A single white 23-year-old male, regular job as a bricklayer, with a history of chronic alcohol abuse, showed up at the emergency department complaining of abdominal pain with colic, weakness, vomiting and diarrhea with black feces. All the symptoms had a duration of two to three weeks, and had been recurrent for the last two years, with calming during interval periods of two to three weeks. Abdominal radiograms showed a bullet lodged in the left hip, with a neat bursogram of the whole synovial capsule. A course of chelating treatment using calcium versenate (EDTACaNa2 intravenously was started. After the chelation therapy the patient had recurrence of his symptoms and a radical solution for the chronic mobilization of lead was considered. A hip arthroplasty procedure was performed, leading to complete substitution of the left hip.

  16. Magnetoresistance oscillations in topological insulator microwires contacted with normal and superconducting leads

    Science.gov (United States)

    Konopko, Leonid; Nikolaeva, Albina; Huber, Tito E.; Rogacki, Krzysztof

    2018-05-01

    Recent efforts to detect and manipulate Majorana fermions in solid state devices have employed topological insulator (TI) nanowires proximity coupled to superconducting (SC) leads. This combination holds some promises for the fundamental physics and applications. We studied the transverse magnetoresistance (MR) of polycrystal Bi2Te2Se and single-crystal Bi0.83Sb0.17 TI microwires contacted with superconducting In2Bi leads. Bi2Te2Se has a simple band structure with a single Dirac cone on the surface and a large non-trivial bulk gap of 300 meV. The semiconducting alloy Bi0.83Sb0.17 is a strong topological insulator due to the inversion symmetry of bulk crystalline Bi and Sb. To study the TI/SC interface, we prepared Bi2Te2Se and Bi0.83Sb0.17 glass-coated microwire samples using superconducting alloy In2Bi (Tc = 5.6 K) to provide a contact of one side of the microwires with copper leads and gallium to provide a contact of the other side of microwires with copper leads. The MR oscillations equidistant in a transverse magnetic field (up to 1 T) at the TI/SC interface were observed at various temperatures (4.2 K-1.5 K) in both the Bi2Te2Se and Bi0.83Sb0.17 samples. In the Bi2Te3 sample with a diameter of d = 17 μm, this oscillations exist with a period of ΔB = 18 mT; in the Bi0.83Sb0.17 sample with d = 1.7 μm MR oscillations are characterized by a period of ΔB = 46 mT. The observed oscillations cannot be referred to the Shubnikov de Haas oscillations because they are not periodic in an inverse magnetic field and their amplitude decreases with increasing magnetic field. Most probably, transverse MR oscillations arise owing to the appearance of highly conducting edge states on the planar boundary of SC/TI.

  17. Global Scouts

    National Research Council Canada - National Science Library

    Wagner, Robert W; Hall, Michael T

    2006-01-01

    One result of the Battle of Mogadishu, 3-4 October 1993, in which 18 American soldiers died and 73 were wounded, was the development and implementation of Tactical Combat Casualty Care (TCCC) Guidelines...

  18. Role of Airborne Lead in Increased Body Burden of Lead in Hartford Children*

    Science.gov (United States)

    Lepow, Martha L.; Bruckman, Leonard; Rubino, Robert A.; Markowitz, Steven; Gillette, Marybeth; Kapish, Janet

    1974-01-01

    The ingestion of airborne lead fallout is the mechanism responsible for increased lead body burdens found in 10 urban Connecticut children. The mean indoor lead levels found in housedust was 11,000 μg/g; highest concentrations occurred on windowsills and in floor dust. The mean lead content of Hartford street dirt was 1,200 μg/g; levels were highest near the street and next to the buildings. The mean lead concentration of hand samples taken from the subject children was 2,400 μg/g; the mean weight of hand samples was 11 mg. The concentration of lead in dirt and househould dust was high enough to theoretically result in excessive lead accumulation in young children who are putting their dusty, dirty hands in their mouths during play. While we believe that lead emitted from automobiles contributes significantly to air, dirt and dust lead levels the environmental impact of reducing or eliminating lead from gasoline is not yet completely understood. PMID:4133903

  19. The early period of the universal Fermi interaction

    International Nuclear Information System (INIS)

    Tiomno, J.

    1984-01-01

    A critical analysis of the contributions which lead, in the early period, to the discovery of the universality of Fermi-type weak interactions is made. In particular the current references to this universality as 'Puppi's triangle' are shown to be incorrect. (Author) [pt

  20. Cellular lead toxicity and metabolism in primary and clonal osteoblastic bone cells

    International Nuclear Information System (INIS)

    Long, G.J.; Rosen, J.F.; Pounds, J.G.

    1990-01-01

    A knowledge of bone lead metabolism is critical for understanding the toxicological importance of bone lead, as a toxicant both to bone cells and to soft tissues of the body, as lead is mobilized from large reservoirs in hard tissues. To further understand the processes that mediate metabolism of lead in bone, it is necessary to determine lead metabolism at the cellular level. Experiments were conducted to determine the intracellular steady-state 210 Pb kinetics in cultures of primary and clonal osteoblastic bone cells. Osteoblastic bone cells obtained by sequential collagenase digestion of mouse calvaria or rat osteosarcoma (ROS 17/2.8) cells were labeled with 210 Pb as 5 microM lead acetate for 20 hr, and kinetic parameters were determined by measuring the efflux of 210 Pb from the cells over a 210 -min period. The intracellular metabolism of 210 Pb was characterized by three kinetic pools of 210 Pb in both cell types. Although the values of these parameters differed between the primary osteoblastic cells and ROS cells, the profile of 210 Pb was remarkably similar in both cell types. Both types exhibited one large, slowly exchanging pool (S3), indicative of mitochondrial lead. These data show that primary osteoblastic bone cells and ROS cells exhibit similar steady-state lead kinetics, and intracellular lead distribution. These data also establish a working model of lead kinetics in osteoblastic bone cells and now permit an integrated view of lead kinetics in bone

  1. Lead nitrate induced changes in the thyroid physiology of the catfish Clarias batrachus (L)

    International Nuclear Information System (INIS)

    Katti, S.R.; Sathyanesan, A.G.

    1987-01-01

    Chronic exposure of Clarias batrachus to sublethal dose of 5 ppm lead nitrate for a period of 150 days impaired thyroid function. Histological observations revealed hypertrophy, increased cell height, vacuolation, and reduction of colloid. The thyrotrophs of the pituitary also exhibited hypertrophy. Radioiodine ( 131 I) uptake was significantly lowered. Fish exposed to 5, 10, and 25 ppm of lead nitrate for 7 days also exhibited significant reduction in 131 I uptake which was dose dependent. These findings suggest that lead nitrate impairs thyroid function involving the hypothalamohypophysiothyroid axis

  2. Bulk diffusion and solubility of silver and nickel in lead, lead-silver and lead-nickel solid solutions

    International Nuclear Information System (INIS)

    Amenzou-Badrour, H.; Moya, G.; Bernardini, J.

    1988-01-01

    The results of a study of solubility and bulk diffusion of /sup 110/Ag and /sup 63/Ni in lead, lead-silver and lead-nickel solid solutions in the temperature range 220 to 88 0 C are reported. Owing to the low solubility of silver and nickel in lead, Fick's solution corresponding to the boundary condition of a constant concentration of solute at the surface has been used. Depth profile concentration analysis suggests a fundamental difference between the diffusion mechanisms of silver and nickel. Since silver penetration profiles in pure lead give diffusion coefficients independent of the penetration depth and silver concentration, it is suggested that slight decreases of silver diffusivity in lead-silver solid solutions have no significance. This implies that the interstitial silver atoms do not associate significantly with each other to form Ag-Ag dimers. In contrast, different behaviors of /sup 63/Ni depth profile concentration in pure lead and saturated PbNi solid solutions agree with a Ni-Ni interaction leading to the formation of less mobile dimers near the surface in pure lead

  3. Lead and osteoporosis: Mobilization of lead from bone in postmenopausal women

    Energy Technology Data Exchange (ETDEWEB)

    Silbergeld, E.K. (Environmental Defense Fund, WA (USA)); Schwartz, J. (Environmental Protection Agency, Washington, DC (USA)); Mahaffey, K. (National Institute of Environmental Health Sciences, Research Triangle Park, NC (USA))

    1988-10-01

    Although it has been known that humans accumulate lead in bone, mineralized tissue has been considered primarily as a sequestering compartment and not as a site of toxic action for lead. However, experimental data indicate that bone lead can be released during conditions of demineralization, such as pregnancy and lactation. We have examined lead status in women, before and after menopause, using the NHANES II dataset compiled between 1976 and 1980. In 2981 black and white women there was a highly significant increase in both whole blood and calculated plasma lead concentrations after menopause. The results indicate that bone lead is not an inert storage site for absorbed lead. Moreover, lead may interact with other factors in the course of postmenopausal osteoporosis, to aggravate the course of the disease, since lead is known to inhibit activation of vitamin D, uptake of dietary calcium, and several regulatory aspects of bone cell function. The consequences of this mobilization may also be of importance in assessing the risks of maternal lead exposure to fetal and infant health.

  4. Safe leads and lead changes in competitive team sports

    Science.gov (United States)

    Clauset, A.; Kogan, M.; Redner, S.

    2015-06-01

    We investigate the time evolution of lead changes within individual games of competitive team sports. Exploiting ideas from the theory of random walks, the number of lead changes within a single game follows a Gaussian distribution. We show that the probability that the last lead change and the time of the largest lead size are governed by the same arcsine law, a bimodal distribution that diverges at the start and at the end of the game. We also determine the probability that a given lead is "safe" as a function of its size L and game time t . Our predictions generally agree with comprehensive data on more than 1.25 million scoring events in roughly 40 000 games across four professional or semiprofessional team sports, and are more accurate than popular heuristics currently used in sports analytics.

  5. Heavy metals, especially lead, deposition recorded in an ombrotrophic peat bog near Manchester, United Kingdom

    Science.gov (United States)

    Le Roux, G.; Weiss, D.; Cheburkin, A.; Rausch, N.; Grattant, J.; Krachler, M.; Shotyk, W.

    2003-05-01

    A peat monolith representing up to 4,000 years of peat accumulation near Manchester, England, was collected. Major and trace elements were analysed with XRF and for Cd and Pb in the deeper samples with GF-AAS following acid digestion. Pb isotopic composition was measured with TIMS and ICP-MS. The results show a pollution since the Roman Period due to local lead sources and an increase in lead pollution in the last century due to leaded gasoline as fingerprinted by Pb isotopic signatures.

  6. Activity of lead deposited in the tissues in conditions of occupational lead exposure

    Energy Technology Data Exchange (ETDEWEB)

    1974-01-01

    The author measured urinary excretion of delta-aminolevulinic acid (ALA), coproporphyrins and lead, before and after administration of chelating agents (CaEDTA and D-penicillamine) to subjects presenting clinical symptoms of lead poisoning and workers occupationally exposed to lead. He found a great increase in lead following its mobilization in subjects with lead poisoning who had previously shown a high level of haemoglobin precursors and a low urinary lead level. In these subjects ALA excretion was proportional to the duration of exposure. A correlation was found between urinary ALA and coproporphyrins, on the one hand, and lead excretion after provocation, on the other. This suggests that the lead deposited in the tissues, as well as that in circulation, retains all its activity.

  7. Motor activity changes induced by sub-encephalopathic lead exposure during different developmental phases in rats

    International Nuclear Information System (INIS)

    Van Rooyen, J.M.; Offermeier, J.; Brand, L.; Botha, F.; Rossouw, J.; Lategan, A.J.; Botes, M.S.

    1988-01-01

    Two groups of rats were exposed to lead (0,2% lead acetate in drinking water) for periods of 21 days during different developmental phases. Lead exposure was initiated on day 1 and day 22 after birth, for rats in groups 1 and 2, respectively. Measurements of locomotor activity (LA) and [ 3 H]spiperone binding assays were performed on day 50 after birth. Lead exposure resulted in the potentiation of the LA effects of 5 mg/kg apomorphine without altering the LA effects of 50 mg/kg piribedil in group 1. Lead exposure resulted in an attenuation of the LA effects of apomorphine and piribedil in group 2. Lead exposure did not alter the K D and B max values of [ 3 H]spiperone in membranes prepared from the rat striatum or nucleus accumbens

  8. Analysis of arrhythmic events is useful to detect lead failure earlier in patients followed by remote monitoring.

    Science.gov (United States)

    Nishii, Nobuhiro; Miyoshi, Akihito; Kubo, Motoki; Miyamoto, Masakazu; Morimoto, Yoshimasa; Kawada, Satoshi; Nakagawa, Koji; Watanabe, Atsuyuki; Nakamura, Kazufumi; Morita, Hiroshi; Ito, Hiroshi

    2018-03-01

    Remote monitoring (RM) has been advocated as the new standard of care for patients with cardiovascular implantable electronic devices (CIEDs). RM has allowed the early detection of adverse clinical events, such as arrhythmia, lead failure, and battery depletion. However, lead failure was often identified only by arrhythmic events, but not impedance abnormalities. To compare the usefulness of arrhythmic events with conventional impedance abnormalities for identifying lead failure in CIED patients followed by RM. CIED patients in 12 hospitals have been followed by the RM center in Okayama University Hospital. All transmitted data have been analyzed and summarized. From April 2009 to March 2016, 1,873 patients have been followed by the RM center. During the mean follow-up period of 775 days, 42 lead failure events (atrial lead 22, right ventricular pacemaker lead 5, implantable cardioverter defibrillator [ICD] lead 15) were detected. The proportion of lead failures detected only by arrhythmic events, which were not detected by conventional impedance abnormalities, was significantly higher than that detected by impedance abnormalities (arrhythmic event 76.2%, 95% CI: 60.5-87.9%; impedance abnormalities 23.8%, 95% CI: 12.1-39.5%). Twenty-seven events (64.7%) were detected without any alert. Of 15 patients with ICD lead failure, none has experienced inappropriate therapy. RM can detect lead failure earlier, before clinical adverse events. However, CIEDs often diagnose lead failure as just arrhythmic events without any warning. Thus, to detect lead failure earlier, careful human analysis of arrhythmic events is useful. © 2017 Wiley Periodicals, Inc.

  9. Atmospheric lead fallout over the last century recorded in Gulf of Lions sediments (Mediterranean Sea)

    International Nuclear Information System (INIS)

    Miralles, J. . E-mail jmiralles@wanadoo.fr; Veron, A.J.; Radakovitch, O.; Deschamps, P.; Tremblay, T.; Hamelin, B.

    2006-01-01

    Six marine sediment cores from the Gulf of Lions continental slope (700-1700 m water depth) were analyzed for stable lead isotopes and 21 Pb geochronology in order to reconstruct lead atmospheric fallout pattern during the last century. The detrital lead contribution is 25 μg g -1 and the mean sediment anthropogenic inventory is 110 ± 7 μg cm -2 , a little bit higher than atmospheric deposition estimate. Anthropogenic lead accumulation in sediments peaked in early 1970s (1973 ± 2) in agreement with lead emissions features. For the period 1986-1997, the sediment signal also reflect the decrease of atmospheric lead described by independent atmospheric fallout investigations. The anthropogenic Pb deposition in the late 1990s was similar to the 1950s deposition, attesting thus of the output of European environmental policies

  10. Hotspots of gross emissions from the land use sector: patterns, uncertainties, and leading emission sources for the period 2000-2005 in the tropics

    Science.gov (United States)

    Roman-Cuesta, Rosa Maria; Rufino, Mariana C.; Herold, Martin; Butterbach-Bahl, Klaus; Rosenstock, Todd S.; Herrero, Mario; Ogle, Stephen; Li, Changsheng; Poulter, Benjamin; Verchot, Louis; Martius, Christopher; Stuiver, John; de Bruin, Sytze

    2016-07-01

    According to the latest report of the Intergovernmental Panel on Climate Change (IPCC), emissions must be cut by 41-72 % below 2010 levels by 2050 for a likely chance of containing the global mean temperature increase to 2 °C. The AFOLU sector (Agriculture, Forestry and Other Land Use) contributes roughly a quarter ( ˜ 10-12 Pg CO2e yr-1) of the net anthropogenic GHG emissions mainly from deforestation, fire, wood harvesting, and agricultural emissions including croplands, paddy rice, and livestock. In spite of the importance of this sector, it is unclear where the regions with hotspots of AFOLU emissions are and how uncertain these emissions are. Here we present a novel, spatially comparable dataset containing annual mean estimates of gross AFOLU emissions (CO2, CH4, N2O), associated uncertainties, and leading emission sources, in a spatially disaggregated manner (0.5°) for the tropics for the period 2000-2005. Our data highlight the following: (i) the existence of AFOLU emissions hotspots on all continents, with particular importance of evergreen rainforest deforestation in Central and South America, fire in dry forests in Africa, and both peatland emissions and agriculture in Asia; (ii) a predominant contribution of forests and CO2 to the total AFOLU emissions (69 %) and to their uncertainties (98 %); (iii) higher gross fluxes from forests, which coincide with higher uncertainties, making agricultural hotspots appealing for effective mitigation action; and (iv) a lower contribution of non-CO2 agricultural emissions to the total gross emissions (ca. 25 %), with livestock (15.5 %) and rice (7 %) leading the emissions. Gross AFOLU tropical emissions of 8.0 (5.5-12.2) were in the range of other databases (8.4 and 8.0 Pg CO2e yr-1 in FAOSTAT and the Emissions Database for Global Atmospheric Research (EDGAR) respectively), but we offer a spatially detailed benchmark for monitoring progress in reducing emissions from the land sector in the tropics. The location of

  11. The period-age relation for cepheids

    International Nuclear Information System (INIS)

    Efremov, Yu.N.

    1978-01-01

    The list of 119 cepheid-members of 55 clusters and associations of the Magellanic Clouds, the Galaxy, and M31 is given. The period-age relation is found from the data on 64 cepheids in 29 clusters for which the age determinations are available, the ages of extragalactic clusters were determined mainly from their integral colours. The U-B colours are found to be of much better age parameters than the B-V ones. The composite period-age relation agrees well with the theoretical one. The observed dispersion of the period-age relation leads to an estimate of the age dispersion about 1x10 7 years in the associations. Some peculiarities of the cepheids with the shortest periods amongst others in the same clusters are probably explained if they are overtone pulsators. The period-age relation may be used for an investigation of the recent history of star formation in the galaxies. This relation allows to determine the age gradient across the spiral arm in M31 which is in agreement with the density wave theory predictions. The distribution of cepheids in our Galaxy and neighbouring galaxies is consistent with the conception of star formation lasting for some dozen million years in cells with a dimension of some hundreds of parsecs

  12. European observatory of the energy markets. Period 2004 and winter 2004/05; Observatoire European des marches de l'energie. Periode 2004 et hiver 2004/05

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    The report underlines for the studied period many tendencies which could compromise the supplying safety: the prices increase of the primary energies, the production margins decrease during the peak period, the poor progression of the frontier exchange, and a weak of a long dated vision leading to the investments deficit in the infrastructures.

  13. Lead inclusions in aluminium

    International Nuclear Information System (INIS)

    Johnson, E.; Johansen, A.; Sarholt-Kristensen, L.; Andersen, H.H.; Grabaek, L.; Bohr, J.

    1990-01-01

    Ion implantation at room temperature of lead into aluminum leads to spontaneous phase separation and formation of lead precipitates growing topotactically with the matrix. Unlike the highly pressurized (∼ 1-5 GPa) solid inclusions formed after noble gas implantations, the pressure in the lead precipitates is found to be less than 0.12 GPa. Recently the authors have observed the result that the lead inclusions in aluminum exhibit both superheating and supercooling. In this paper they review and elaborate on these results. Small implantation-induced lead precipitates embedded in an aluminum matrix were studied by x-ray diffraction

  14. TrSDB: a proteome database of transcription factors

    Science.gov (United States)

    Hermoso, Antoni; Aguilar, Daniel; Aviles, Francesc X.; Querol, Enrique

    2004-01-01

    TrSDB—TranScout Database—(http://ibb.uab.es/trsdb) is a proteome database of eukaryotic transcription factors based upon predicted motifs by TranScout and data sources such as InterPro and Gene Ontology Annotation. Nine eukaryotic proteomes are included in the current version. Extensive and diverse information for each database entry, different analyses considering TranScout classification and similarity relationships are offered for research on transcription factors or gene expression. PMID:14681387

  15. Skautský cestovní ruch

    OpenAIRE

    Jošt, Vojtěch

    2008-01-01

    My thesis is concerned about organization called "Junak" -- Czech republic union of scouts as the one of the largest organizations in Czech rep. The important part of its program is organizing meetings and creating events which fulfill a definition of an organized tourism. So we can speak about tourism caused by Junak organization, the so called scout tourism. Furthermore my thesis is focused on concrete indicators evaluating content and the structure of the scout tourism.

  16. [Geographical distribution of mortality by Parkinson's disease and its association with air lead levels in Spain].

    Science.gov (United States)

    Santurtún, Ana; Delgado-Alvarado, Manuel; Villar, Alejandro; Riancho, Javier

    2016-12-02

    Parkinson's disease (PD) is the second most common neurodegenerative disease, and the etiology of its sporadic form is unknown. The present study analyzes the temporal and spatial variations of mortality by PD in Spain over a period of 14 years and its relationship with lead concentration levels in the atmosphere. An ecological study was performed, in which deaths by PD and age group in 50 Spanish provinces between 2000 and 2013 were analyzed. The annual trend of PD mortality was assessed using the non-parametric Spearman's Rho test. Finally, the relationship between lead concentration levels in the air and mortality by PD was evaluated. Between 2000 and 2013, 36,180 patients with PD died in Spain. There is an increasing trend in mortality through PD over the study period (P<.0001). La Rioja, Asturias, Basque Country and the Lower Ebro valley were the regions with the highest values of PD mortality. Those regions with the highest lead concentrations also showed higher mortality by this disease in people over 64 (P=.02). Over our period of study, there has been an increase in mortality through PD in Spain, with the northernmost half of the country registering the highest values. Mortality in men was higher than mortality in women. Moreover, a direct correlation was found between lead levels in the air and mortality through PD. Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

  17. Chaos to periodicity and periodicity to chaos by periodic perturbations in the Belousov-Zhabotinsky reaction

    International Nuclear Information System (INIS)

    Li Qianshu; Zhu Rui

    2004-01-01

    A three-variable model of the Belousov-Zhabotinsky reaction system subject to external sinusoidal perturbations is investigated by means of frequency spectrum analysis. In the period-1 window of the model, the transitions from periodicity to chaos are observed; in the chaotic window, the transitions from chaos to periodicity are found. The former might be understood by the circle map of two coupled oscillators, and the latter is partly explained by the resonance between the main frequency of the chaos and the frequency of the external periodic perturbations

  18. Lead poisoning in calves

    Energy Technology Data Exchange (ETDEWEB)

    Reeves, J E

    1964-01-01

    Over a three-year period a farmer lost seven calves in their second month of age. One year ago a tentative diagnosis of rabies was given and a brain was submitted to the Health of Animals Division for examination. No Negri bodies were found. The owner stated that the calves first appeared listless and later exhibited severe nervous signs. Deaths occurred in from one to 24 hours after onset of signs. Appetite and bowel movements were normal. There was no increase in temperature. The calf would lie quietly for an interval, then rise, run down the alley, press against a wall, and go into a convulsion. It acted as if it were in severe pain and during one of the intermittent convulsions, it jumped over a three-foot partition. This calf was sent to the Regional Veterinary Laboratory at Brighton for necropsy. The calf had been dead for 72 hours when submitted to the laboratory. The only gross findings were of mild pleurisy and hemorrhage on the kidney. A tentative diagnosis of lead poisoning was offered and specimens sent to the Division of Pharmacology and Toxicology, Ontario Veterinary College.

  19. Routine lead isotope determinations using a lead-207-lead-204 double spike: a long-term assessment of analytical precision and accuracy

    International Nuclear Information System (INIS)

    Woodhead, J.D.; McCulloch, M.T.; Volker, F.

    1995-01-01

    Lead-isotope data obtained on a multicollector mass spectrometer over a four year period using a 207 Pb- 204 Pb double spike to correct for the effects of mass discrimination, are reported. Considerable improvements in both precision and accuracy over conventional correction procedures were noted, without recourse to rigorous loading or run conditions. An external precision in 206 Pb/ 204 Pb, 207 Pb/ 204 Pb and 208 Pb/ 204 Pb ratios ± 0.003, 0.003 and 0.01 (2 x standard deviation), respectively, is routinely obtainable independent of minor variations in loading and run parameters. (author)

  20. Lead pollution: lead content in milk from cows fed on contaminated forages

    Energy Technology Data Exchange (ETDEWEB)

    Sapetti, C; Arduino, E; Durio, P

    1973-01-01

    Lead toxicity is reviewed, and the history of the lead poisoning is described. Much of the lead pollution in soil is due to automobile exhaust. Two milk cows were fed forage with added lead acetate. The 20 kg of lead corresponded to 50 ppm, a level that is often found in hays near major highways. The cows milk was then analyzed for lead content. During the first and second phase of administration of lead salts, the milk cows did not show any evident symptoms of intoxication. The lead in the milk did have a marked correlation with the administered lead. The lead doses did not last long enough for chronic symptoms to begin. The dosage of lead in milk, due to the facility of drawing samples and the relevant levels of response, could represent a valid method for diagnosing incipient chronic intoxications.

  1. [Lead point as a poor prognostic factor in the therapy of invagination in children].

    Science.gov (United States)

    Djordjević, I M; Milićević, R; Djordjević, N; Karanikolić, A D; Ignjatović, N

    2007-01-01

    Invagination is specific form of bowel opstruction that is seen in 1-4 children per 1000 births, usually in the period from 3 to 12 months of age. In 90-95 % reason for invagination in unknown so we called this forms idiopathic. In 5-10% invagination is caused by specific leading point. THE AIM of this retrospective study was to determinate prognostic valye of used biochemical tests (hemograms, glucosa, electrolites ( levels of Na+, K+, Ca+ and Cl-) and to prove bad influence of existing "leading point" in therapy of invagination (weather it will be surgical or hydrostatic desinvagination). We analised 65 patients with invagination. We devided all our patients into 2 groups: first group consisted patients with idiopathic forms of invagination, and the other one were patients with invagination coused by specific leading point. RESULTS proved that leading point in invagination has great implications on clinical presentation, laboratory results, diagnostic and therapeutic procedure, and finaly in prognosis.

  2. Lead elimination by ICRF 158 in rats after chronic lead exposure

    Energy Technology Data Exchange (ETDEWEB)

    Witting, U; Hultsch, E

    1981-02-01

    Lead elimination by ICRF 158, a lipophilic derivative of ethylene-diaminetetra-acetate (EDTA), was investigated in rats after chronic lead exposure. The animals had received a lead concentration of 550 ppm in their drinking water for 140 days. Subsequent treatment with ICRF 158 for 30 days led to increased mobilization and elimination of incorporated lead, and the lead-induced inhibition of hemosynthesis was removed. ICR 158 produced no renal damage in excess to lead-induced tubular nephrosis. Separate toxicity tests in mice demonstrated that is less toxic than CaNa/sub 2/EDTA. ICRF 158 does not form stable complexes with lead ions in vitro. The mechanism of action of this lipophilic EDTA derivative is compared to that of its hydrophilic correspondent, the chelating agent CaNa/sub 2/EDTA.

  3. Radioisotope immersion probe for continuous or discrete measurements of sulphur in crude oils and lead in refinery products

    International Nuclear Information System (INIS)

    Teller, S.

    1976-01-01

    The sulfur content of fuel oils and the lead content of gasolines can be determined in a single measurement by a simultaneous detection of scattered and transmitted low-energy x-ray. A prototype immersion probe was developed, and a precison of 0.02 percent sulfur and 20 ppM lead was obtained for a counting period of 1 minute

  4. Periodic orbits of the hydrogen molecular ion and their quantization

    International Nuclear Information System (INIS)

    Duan, Y.; Yuan, J.; Bao, C.

    1995-01-01

    In a classical study of the hydrogen molecular ion beyond the Born-Oppenheimer approximation (BOA), we have found that segments of trajectories resemble that of the Born-Oppenheimer approximation periodic orbits. The importance of this fact to the classical understanding of chemical bonding leads us to a systematic study of the periodic orbits of the planar hydrogen molecular ion within the BOA. Besides introducing a classification scheme for periodic orbits, we discuss the convergence properties of families of periodic orbits and their bifurcation patterns according to their types. Semiclassical calculations of the density of states based on these periodic orbits yield results in agreement with the exact quantum eigenvalues of the hydrogen molecular ion system

  5. Lead Contamination and Microbial Lead Tolerance in Soils at Major ...

    African Journals Online (AJOL)

    Devika

    ABSTRACT: Lead pollution and lead tolerance levels of microbes in soil at major road junctions in Benin. City were investigated. Results revealed that distance from the road junctions affected the concentrations of lead in soil, as well as the microbial population density and types of microbes present in the soil. The highest ...

  6. Lead Contamination and Microbial Lead Tolerance in Soils at Major ...

    African Journals Online (AJOL)

    Lead pollution and lead tolerance levels of microbes in soil at major road junctions in Benin City were investigated. Results revealed that distance from the road junctions affected the concentrations of lead in soil, as well as the microbial population density and types of microbes present in the soil. The highest concentrations ...

  7. Effect of pH, temperature, and lead concentration on the bioremoval of lead from water using Lemna minor.

    Science.gov (United States)

    Uysal, Yağmur; Taner, Fadime

    2009-09-01

    This study examined the ability of the aquatic plant Lemna minor (duckweed) to remove soluble lead under various laboratory conditions. In a batch process L. minor was exposed to different pH values (4.5-8.0) and temperature (15-35 degrees C) in presence of different lead concentrations (0.1-10.0 mg L(-1)) for 168 h. The amount of biomass obtained in the study period on a dry weight basis, the concentrations of lead in tissue and in medium and net uptake of lead by Lemna all have been determined in each condition. The percentages of lead uptake ratios (PMU) and bioconcentration factors (BCF) were also calculated for these conditions. Bioaccumulated lead concentrations and the PMU were obtained at lowest pH of 4.5, and at 30 degrees C. The highest accumulated lead concentration was found at pH 4.5 as 3.599 mg Pb g(-1) in 10.0 mg L(-1). It decreased to pH 6.0, but it did not change at pH 6.0-8.0 range. The maximum lead accumulation was obtained at 30 degrees C as 8.622 mg Pb g(-1) in 10 mg L(-1) at pH 5.0, and the minimum was at 15 degrees C as 0.291 mg g(-1) in 0.1 mg L(-1). Lead accumulation gradually increased with increasing lead in medium, but the opposite trend was observed for PMU. Lead accumulation increased up to 50 mg L(-1), but did not change significantly in the 50.0-100.0 mg L(-1) range. The lead uptake from water was modeled and the equation fit the experimental data very well

  8. Lead levels in some biological samples of auto-mechanics in Abeokuta, Nigeria.

    Science.gov (United States)

    Babalola, O O; Ojo, L O; Aderemi, M O

    2005-12-01

    Lead levels were determined in the blood, scalp hair and fingernails of 38, all male auto-mechanics (aged 18-45 years) from Abeokuta, South-western Nigeria. The subjects were classified into four sub-groups based on the period of exposure namely: 1-5, 6-10, 11-15, and >16 years. Thirty-two occupationally unexposed subjects (mainly office workers) served as the control. The weight, height and body mass indexes of all subjects were noted, in addition to other information obtained through structured questionnaire. The mean values of blood lead (BPb), hair lead (HPb) and fingernail lead (NPb) of the occupationally exposed subjects (n=38) were 48.50 +/- 9.08 microg/dL, 17.75 +/- 5.16 microg/g, and 5.92 +/- 3.30 microg/g respectively, while the corresponding mean values for these parameters in the control subjects (n = 32) were 33.(,5 +/- 10.09 microg/dL, 14.30 +/- 5.90 microg/g and 5.31 +/- 2.77 microg/g respectively. The differences in BPb and HPb levels of the two groups were statistically significant (P <0.05 and P <0.01 respectively), while that of NPb was not significant. The levels of lead in the biological samples appeared to have no relationship with the number of years on the job. From these results, it was obvious that the higher levels of lead in the biological samples of test subjects, compared with those of the controls were from environmental sources.

  9. Immunological effects of CaEDTA injection: observations in two lead workers.

    Science.gov (United States)

    Sata, F; Araki, S; Sakai, T; Nakata, A; Yamashita, K; Morita, Y; Tanigawa, T; Miki, A

    1997-12-01

    To evaluate the effects of calcium disodium ethylenediamine tetraacetate (CaEDTA) injection on human immune system in relation to exposure to lead, we administered CaEDTA by intravenous injection for 1 hr three times (three consecutive days) a week to two male lead workers. They had been engaged in recycling lead for 31 and 22 years, aged 61 and 53 years (workers 1 and 2), respectively. Before the treatment of CaEDTA, their blood lead concentrations (PbB) were 81 and 68 micrograms/dl, respectively. The administration of CaEDTA had been carried out to worker 1 for 10 weeks and to worker 2 for 6 weeks. A significant decrease in PbB between before and after three-times CaEDTA injection was found in both workers. Significant increases in IgG, IgA, IgM, CD8+, and CD57+ cells were found in worker 1. A significant increase in IgD was found in worker 2. During the study period, IgG in worker 1 and CD4+ cells in worker 2 were gradually increasing. There was a significant negative correlation between IgG and PbB in worker 1. It is suggested that the immunological function such as antibody formation in lead workers might be improved by CaEDTA injection.

  10. Directly smelted lead-tin alloys: A historical perspective

    Science.gov (United States)

    Dube, R. K.

    2010-08-01

    This paper discusses evidence related to the genesis and occurrence of mixed lead-tin ore deposit consisting of cassiterite and the secondary minerals formed from galena. These evidences belong to a very long time period ranging from pre-historic to as late as the nineteenth century a.d. This type of mixed ore deposits was smelted to prepare lead-tin alloys. The composition of the alloy depended on the composition of the starting ore mixture. A nineteenth century evidence for the production of directly smelted lead-tin alloys in southern Thailand is discussed. A unique and rather uncommon metallurgical terminology in Sanskrit language— Nāgaja—was introduced in India for the tin recovered from impure lead. This suggests that Indians developed a process for recovering tin from lead-tin alloys, which in all probability was based on the general principle of fire refining. It has been shown that in the context of India the possibility of connection between the word Nāgaja and the directly smelted lead-tin alloys cannot be ruled out.

  11. The refining of secondary lead for use in advanced lead-acid batteries

    International Nuclear Information System (INIS)

    Ellis, Timothy W.; Mirza, Abbas H.

    2010-01-01

    Secondary lead, i.e. material produced by the recycling of lead-acid batteries has become the primary source of lead in much of the world. This has been important to the secondary lead industry as other uses have dwindled, e.g. lead based pigments, chemicals, fuel additives, solders and CRT glasses. Presently, battery manufacturing accounts for greater than 80% of lead consumption while recycled lead accounts for approximately the same market share of lead supply. These two facts strongly demonstrate the battery manufacturing and recycled lead are intimately coupled in everyday life. In this paper we will explore how recycled lead has become the material of choice for battery construction through the development of a recovery and refining process that exceeds the industries requirements. Particular focus will be on addressing the results presented by Prengaman on the effects of contaminant or tramp elements on gassing in lead-acid batteries. (author)

  12. Science education beyond the classroom

    International Nuclear Information System (INIS)

    Harle, E.J.; Van Natta, D.; Powell, M.L.

    1993-01-01

    The Yucca Mountain Site Characterization Project (YMP) sponsors a variety of classroom-oriented projects and activities for teachers who request them. Also available, though, are extra-curricular programs. One notably successful program is a workshop designed to award girl and boy scouts with geology and atomic energy merit badges. There was a tremendous response to this workshop--it attracted 450 requests within the first week of its announcement. Since October 1991, the YMP has sponsored five such girl scout workshops and four boy scout workshops, attended by a total of 400 scouts. These workshops demonstrate that highly technical subjects can be taught simply through hands-on activities. The idea behind them is not to teach scouts what to think but, rather, how to think. For adults meanwhile, the YMP offers a monthly lecture series, with each lecture averaging 45 minutes in length with 35 people in attendance. These lectures center on such subjects as volcanoes, earthquakes and hydrology. They are usually delivered by YMP technical staff members, who have learned that complex technical issues are best addressed in a small-group format

  13. Motor activity changes induced by sub-encephalopathic lead exposure during different developmental phases in rats

    Energy Technology Data Exchange (ETDEWEB)

    Van Rooyen, J M; Offermeier, J; Brand, L; Botha, F; Rossouw, J; Lategan, A J; Botes, M S

    1988-05-01

    Two groups of rats were exposed to lead (0,2% lead acetate in drinking water) for periods of 21 days during different developmental phases. Lead exposure was initiated on day 1 and day 22 after birth, for rats in groups 1 and 2, respectively. Measurements of locomotor activity (LA) and (/sup 3/H)spiperone binding assays were performed on day 50 after birth. Lead exposure resulted in the potentiation of the LA effects of 5 mg/kg apomorphine without altering the LA effects of 50 mg/kg piribedil in group 1. Lead exposure resulted in an attenuation of the LA effects of apomorphine and piribedil in group 2. Lead exposure did not alter the K/sub D/ and B/sub max/ values of (/sup 3/H)spiperone in membranes prepared from the rat striatum or nucleus accumbens.

  14. Periodically Driven Array of Single Rydberg Atoms

    Science.gov (United States)

    Basak, Sagarika; Chougale, Yashwant; Nath, Rejish

    2018-03-01

    An array of single Rydberg atoms driven by a temporally modulated atom-field detuning is studied. The periodic modulation effectively modifies the Rabi coupling, leading to unprecedented dynamics in the presence of Rydberg-Rydberg interactions, in particular, blockade enhancement, antiblockades, and state-dependent population trapping. Interestingly, the Schrieffer-Wolf transformation reveals a fundamental process in Rydberg gases, correlated Rabi coupling, which stems from the extended nature of the Rydberg-Rydberg interactions. Also, the correlated coupling provides an alternative depiction for the Rydberg blockade, exhibiting a nontrivial behavior in the presence of periodic modulation. The dynamical localization of a many-body configuration in a driven Rydberg lattice is discussed.

  15. Blood lead and lead-210 origins in residents of Toulouse

    International Nuclear Information System (INIS)

    Servant, J.; Delapart, M.

    1981-01-01

    Blood lead and lead-210 analyses were performed on blood samples from non-smoking residents of Toulouse (city of 400,000 inhabitants). Simultaneous surface soil lead content determinations were carried out by the same procedure on rural zone samples of southwestern France. The observed isotopic ratios were compared in order to evaluate food chain contamination. For an average of 19.7 +- 5.8 μg 100 cc -1 of lead in blood, atmospheric contamination amounts to 20%, estimated as follows: 6% from direct inhalation and 14% from dry deposits on vegetation absorbed as food. The natural levels carried over by the food chain reach 14.9 μg 100 cc -1 and have a 210 Pb/Pb concentration ratio of 0.055 dpmμg -1 . These results lead to a maximum value of 15 μg 100 cc -1 for natural lead in human blood according to the ICRP model. (author)

  16. Dynamics of Solid Body in Magnetic Suspension under Periodic Excitation

    Directory of Open Access Journals (Sweden)

    A. M. Gouskov

    2017-01-01

    Full Text Available The article studies dynamics of ferromagnetic body in hybrid magnetic suspension (HMS. The body is supposed to have one degree of freedom and a nonlinear magnetic force dependence on the current and displacement. The magnetic force induced in the HMS is divided into a passive component and an active one. Specifying the law of current variation in the coil allows us to generate nonlinear oscillations under electromagnet action. To provide periodic excitation the appropriate law of the current variation in the electromagnet coil is proposed. The mathematical model includes external periodic step-excitation. The equation of motion is formed. The scales of similarity are highlighted in the system, and the equation of motion is reduced to dimensionless form.The motion dynamics is studied numerically. The relaxation method was used to determine the periodic motions at different values of dimensionless frequency of the electromagnet excitation as well as to estimate the influence of other dimensionless parameters on the system dynamics. The amplitude-frequency curve analysis allows us to come to conclusion that the nature of system nonlinearity is rigid. Adding the external periodic step-excitation leads to the qualitative change in the nature of movement. This points to the occurrence of bifurcation.

  17. Correlations in particle production in proton-lead and lead-lead collisions at the LHC

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00361447

    In high-energy heavy-ion collisions at the Large Hadron Collider (LHC), a hot and dense state of matter called the Quark-Gluon Plasma (QGP) is formed. The initial collision geometry and the subsequent expansion during the QGP stage result in the correlations of produced particles, through which the properties of the QGP can be investigated. Two analyses based on the geometrical correlations of produced particles, one in proton-lead (p–Pb) collisions and the other in lead-lead (Pb–Pb) collisions, are presented in this thesis. The data analyzed in this thesis were collected with the ALICE detector at the LHC in p– Pb collisions at a nucleon–nucleon center-of-mass energy of 5.02 TeV, and Pb–Pb collisions at a nucleon–nucleon center-of-mass energy of 2.76 TeV. In the forward-central two-particle correlation analysis in p–Pb collisions, two-particle an- gular correlations between trigger particles in the forward pseudorapidity range (2.5 < |η| < 4.0) and associated particles in the central ran...

  18. End-stage renal disease after occupational lead exposure: 20 years of follow-up.

    Science.gov (United States)

    Evans, Marie; Discacciati, Andrea; Quershi, Abdul Rashid; Åkesson, Agneta; Elinder, Carl-Gustaf

    2017-06-01

    Whether low-level exposure to lead may give rise to chronic kidney disease or end-stage renal disease (ESRD) is debated. In this study, we aimed to specifically investigate if low-level occupational exposure to lead was associated with increased incidence of ESRD. The incidence of starting renal replacement therapy as a result of ESRD was examined in a cohort of10 303 lead-workers who had controlled blood lead concentrations due to a compulsory occupational health surveillance programme in Sweden during the time period 1977-1990. The ESRD incidence (obtained through register-linkage) among the lead-exposed workers was compared with the age, sex and calendar period-adjusted expected incidence based on data from the Swedish renal registry. Dose-response association was evaluated in external (general population) and internal (within the occupational cohort) comparisons by highest achieved blood lead level. There were 30 (0.29%) individuals in the cohort who developed ESRD during the median follow-up period of 26.3 years. The standardised incidence ratio (SIR) for ESRD incidence was 0.79 (95% CI 0.54 to 1.13). Among those who achieved the highest blood lead (>41.4 µg/dL), the SIR was 1.01 (0.44 to 1.99). There was no evidence of a dose-response relationship between the maximum achieved blood lead or the cumulative blood lead exposure and ESRD in external or internal comparisons. This study of workers with documented occupational lead exposures followed for 20 years shows no statistically significant association between lead exposure (following the current occupational recommendations for Sweden) and ESRD. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  19. Twenty-five years of biomonitoring lead in the Frankfurt/Main area.

    Science.gov (United States)

    Ballach, Hans-Joachim; Wittig, Rüdiger; Wulff, Svenja

    2002-01-01

    The present study is an example of the historical monitoring of heavy metals. The specific question it aims to explore is: to what extent has the lead content of selected organisms used for biomonitoring in Frankfurt/Main--one of the cities in Germany most heavily affected by automobile traffic--changed as a result of legislation on leaded gasoline? Data on the lead content of the moss species Bryum argenteum Hedw. from the years 1974, 1975 and 1978 and data on the lead content of the outer bark of the ash species Fraxinus excelsior L. from 1973 served as the basis for the repeated measurements. Remeasurement was successful in 76.5% (i.e. 124 trees at 26 growth sites). The study produced the following results: As was expected, the lead content of the short-term accumulator Bryum argenteum Hedw. was distinctly lowered with a decreasing particulate lead concentration. However, the reduction factor varied greatly between the different growth sites. On the other hand, the lead content measured in the outer bark layers of Fraxinus excelsior L. has risen markedly during the past two decades. Whereas in 1973 nearly all trees examined displayed very low concentrations of lead (225 ppm). Various factors have to be taken into account to explain this increase. First of all, bark is a long-term accumulator for heavy metals like lead and its enrichment capacity could have increased as the surface becomes rougher over time. Furthermore, lead is most probably leached out of the bark to a lesser degree now than in the 1970s, owing to the reduced concentration of sulphuric acid in the rain. The dramatic growth of automobile traffic in the Frankfurt/Main area during the period covered by the study undoubtedly plays an important role as well.

  20. A novel flow battery: A lead acid battery based on an electrolyte with soluble lead(II). Part IX: Electrode and electrolyte conditioning with hydrogen peroxide

    Science.gov (United States)

    Collins, John; Li, Xiaohong; Pletcher, Derek; Tangirala, Ravichandra; Stratton-Campbell, Duncan; Walsh, Frank C.; Zhang, Caiping

    Extended cycling of a soluble lead acid battery can lead to problems due to an imbalance in the coulombic efficiency leading to deposits of Pb and PbO2 on the electrodes. Periodic addition of hydrogen peroxide to the electrolyte of the soluble lead acid flow battery largely overcomes several operational problems seen during extended cycling, using a 10 cm × 10 cm parallel plate flow cell. It is shown that this treatment greatly extends the number of cycles that can be achieved with a reasonable energy-, voltage-, and charge efficiency of 54-66%, 71%, and 77-91%.

  1. A novel flow battery: A lead acid battery based on an electrolyte with soluble lead(II). Part IX: Electrode and electrolyte conditioning with hydrogen peroxide

    Energy Technology Data Exchange (ETDEWEB)

    Collins, John; Stratton-Campbell, Duncan [C-Tech Innovation Ltd., Capenhurst, Chester CH1 6EH (United Kingdom); Li, Xiaohong; Tangirala, Ravichandra; Walsh, Frank C.; Zhang, Caiping [Energy Technology Research Group, School of Engineering Sciences, University of Southampton, Highfield, University Road, Southampton SO17 1BJ (United Kingdom); Pletcher, Derek [Electrochemistry and Surface Science Group, School of Chemistry, University of Southampton, Southampton SO17 1BJ (United Kingdom)

    2010-05-01

    Extended cycling of a soluble lead acid battery can lead to problems due to an imbalance in the coulombic efficiency leading to deposits of Pb and PbO2 on the electrodes. Periodic addition of hydrogen peroxide to the electrolyte of the soluble lead acid flow battery largely overcomes several operational problems seen during extended cycling, using a 10 cm x 10 cm parallel plate flow cell. It is shown that this treatment greatly extends the number of cycles that can be achieved with a reasonable energy-, voltage-, and charge efficiency of 54-66%, 71%, and 77-91%. (author)

  2. Tracing temperature in a nanometer size region in a picosecond time period.

    Science.gov (United States)

    Nakajima, Kaoru; Kitayama, Takumi; Hayashi, Hiroaki; Matsuda, Makoto; Sataka, Masao; Tsujimoto, Masahiko; Toulemonde, Marcel; Bouffard, Serge; Kimura, Kenji

    2015-08-21

    Irradiation of materials with either swift heavy ions or slow highly charged ions leads to ultrafast heating on a timescale of several picosecond in a region of several nanometer. This ultrafast local heating result in formation of nanostructures, which provide a number of potential applications in nanotechnologies. These nanostructures are believed to be formed when the local temperature rises beyond the melting or boiling point of the material. Conventional techniques, however, are not applicable to measure temperature in such a localized region in a short time period. Here, we propose a novel method for tracing temperature in a nanometer region in a picosecond time period by utilizing desorption of gold nanoparticles around the ion impact position. The feasibility is examined by comparing with the temperature evolution predicted by a theoretical model.

  3. The Periodic Table as a Tool for Teaching the Nature of Science

    Science.gov (United States)

    Peters, Erin E.; Sterling, Donna R.

    2008-01-01

    Teaching the connectedness of relationships among elements in the Periodic Table is often an overwhelming task, and can result in shallow student understanding. This article contains a series of activities that evoke student prior knowledge about classification, leads them to discover periodicity and other relationships among the characteristics…

  4. The lead and lead-acid battery industries during 2002 and 2007 in China

    Energy Technology Data Exchange (ETDEWEB)

    Chen, H.Y.; Li, A.J.; Finlow, D.E. [Key Lab of Electrochemical Technology on Energy Storage and Power Generation in Guangdong Universities, School of Chemistry and Environment, South China Normal University, Guangzhou 510006 (China)

    2009-06-01

    In the past 15 years, the center of the international lead market has shifted to China. China has become the largest producer of raw and refined lead, plus the largest consumer. This paper reviews the status of the lead and lead-acid battery industries in China, including lead mining, lead refining, secondary lead production, the lead-acid battery industry, new opportunities for lead-acid batteries, and the environmental problems associated with lead and lead-acid batteries. The output of raw and refined lead has increased annually in China, and now accounts for more than 30% of the world total. As a result of a change in the Chinese government's policy regarding the export of lead, plus an increase in the price of lead, the profits of Chinese lead manufacturers were significantly reduced, the trade deficit of the Chinese lead industry increased, the operating rates of lead smelter enterprises greatly reduced, and some small enterprises were forced to shut down. At the present time, an increasing number of enterprises have begun to produce secondary lead, and the scale of production has expanded from tens of tons to tens of thousands of tons. In 2006, the output of secondary lead in China reached 700,000 tons, but outdated technology and equipment limited development of the secondary lead industry. Because of serious pollution problems, raw material shortages, and fierce price competition in the battery market, changes in the development of the lead-acid battery industry have been dramatic; approximately one thousand medium-sized and small lead-acid battery producers have been closed in the past 3 years. The output of large lead-acid battery enterprises has not been reduced, however, as a result of their manufacturing technology and equipment being comparable to those in other advanced industrial countries. In China, the flourishing development of electric bicycles, electric tricycles, and photovoltaic energy systems should provide ongoing opportunities for

  5. The lead and lead-acid battery industries during 2002 and 2007 in China

    International Nuclear Information System (INIS)

    Chen, H.Y.; Li, A.J.; Finlow, D.E.

    2009-01-01

    In the past 15 years, the center of the international lead market has shifted to China. China has become the largest producer of raw and refined lead, plus the largest consumer. This paper reviews the status of the lead and lead-acid battery industries in China, including lead mining, lead refining, secondary lead production, the lead-acid battery industry, new opportunities for lead-acid batteries, and the environmental problems associated with lead and lead-acid batteries. The output of raw and refined lead has increased annually in China, and now accounts for more than 30% of the world total. As a result of a change in the Chinese government's policy regarding the export of lead, plus an increase in the price of lead, the profits of Chinese lead manufacturers were significantly reduced, the trade deficit of the Chinese lead industry increased, the operating rates of lead smelter enterprises greatly reduced, and some small enterprises were forced to shut down. At the present time, an increasing number of enterprises have begun to produce secondary lead, and the scale of production has expanded from tens of tons to tens of thousands of tons. In 2006, the output of secondary lead in China reached 700,000 tons, but outdated technology and equipment limited development of the secondary lead industry. Because of serious pollution problems, raw material shortages, and fierce price competition in the battery market, changes in the development of the lead-acid battery industry have been dramatic; approximately one thousand medium-sized and small lead-acid battery producers have been closed in the past 3 years. The output of large lead-acid battery enterprises has not been reduced, however, as a result of their manufacturing technology and equipment being comparable to those in other advanced industrial countries. In China, the flourishing development of electric bicycles, electric tricycles, and photovoltaic energy systems should provide ongoing opportunities for the

  6. Kinetics of oil saponification by lead salts in ancient preparations of pharmaceutical lead plasters and painting lead mediums.

    Science.gov (United States)

    Cotte, M; Checroun, E; Susini, J; Dumas, P; Tchoreloff, P; Besnard, M; Walter, Ph

    2006-12-15

    Lead soaps can be found in archaeological cosmetics as well as in oil paintings, as product of interactions of lead salts with oil. In this context, a better understanding of the formation of lead soaps allows a follow-up of the historical evolution of preparation recipes and provides new insights into conservation conditions. First, ancient recipes of both pharmaceutical lead plasters and painting lead mediums, mixtures of oil and lead salts, were reconstructed. The ester saponification by lead salts is determined by the preparation parameters which were quantified by FT-IR spectrometry. In particular, ATR/FT-IR spectrometer was calibrated by the standard addition method to quantitatively follow the kinetics of this reaction. The influence of different parameters such as temperature, presence of water and choice of lead salts was assessed: the saponification is clearly accelerated by water and heating. This analysis provides chemical explanations to the historical evolution of cosmetic and painting preparation recipes.

  7. Lactational Lead Exposure Perturbates Androgenesis in Juvenile and Pubertal Wistar Rats

    Directory of Open Access Journals (Sweden)

    Odukoya SOA

    2017-10-01

    Full Text Available Background: High to low lead (Pb concentrations in breast milk has been found to perturb some biological events in the postnatal life. While postnatal Pb exposure has been reported to impair some andrological parameters in mammals, the age-dependent andrological signature of lactational Pb poisoning is not clear. Aims and Objectives: This study investigated the effects of Pb exposure during lactational period on the testicular andrological profiles of rats at certain postlactational ages using varying doses of Pb. Material and Methods: Lactating mothers and their pups were randomly divided into 4 groups comprising 24 pups each. The treatment groups received 10mg/dL, 30mg/dL, and 70mg/dLof lead acetate in their drinking water from postnatal day one (P1 to P21 of the lactational period. The control rats received distilled water. At P22, P60, P90 and P120, the pups from each group were euthanized, testes were collected, homogenized and the supernatant was used to assay for testosterone and oestrogen using standard methods. Results: Lactational lead poisoning was associated with depressed testicular testosterone productions (P<0.05 compared with controls and abnormally high levels of testicular oestrogen. These statistically significant differences (P<0.05 in androgens levels were corrected to near normal with increasing postnatal ages at low doses. Conclusion: These results show that lactational Pb intoxication causes reversible androgenic perturbations at low doses but irreversible damage at high doses during postnatal life. Conclusively, high lactational Pb is associated with post-lactational irreversible impairment of androgenic profiles.

  8. Eryptosis in lead-exposed workers

    International Nuclear Information System (INIS)

    Aguilar-Dorado, Itzel-Citlalli; Hernández, Gerardo; Quintanar-Escorza, Martha-Angelica; Maldonado-Vega, María; Rosas-Flores, Margarita; Calderón-Salinas, José-Víctor

    2014-01-01

    Eryptosis is a physiological phenomenon in which old and damaged erythrocytes are removed from circulation. Erythrocytes incubated with lead have exhibited major eryptosis. In the present work we found evidence of high levels of eryptosis in lead exposed workers possibly via oxidation. Blood samples were taken from 40 male workers exposed to lead (mean blood lead concentration 64.8 μg/dl) and non-exposed workers (4.2 μg/dl). The exposure to lead produced an intoxication characterized by 88.3% less δ-aminolevulinic acid dehydratase (δALAD) activity in lead exposed workers with respect to non-lead exposed workers. An increment of oxidation in lead exposed workers was characterized by 2.4 times higher thiobarbituric acid-reactive substance (TBARS) concentration and 32.8% lower reduced/oxidized glutathione (GSH/GSSG) ratio. Oxidative stress in erythrocytes of lead exposed workers is expressed in 192% higher free calcium concentration [Ca 2+ ] i and 1.6 times higher μ-calpain activity with respect to non-lead exposed workers. The adenosine triphosphate (ATP) concentration was not significantly different between the two worker groups. No externalization of phosphatidylserine (PS) was found in non-lead exposed workers (< 0.1%), but lead exposed workers showed 2.82% externalization. Lead intoxication induces eryptosis possibly through a molecular pathway that includes oxidation, depletion of reduced glutathione (GSH), increment of [Ca 2+ ], μ-calpain activation and externalization of PS in erythrocytes. Identifying molecular signals that induce eryptosis in lead intoxication is necessary to understand its physiopathology and chronic complications. - Graphical abstract: Fig. 1. (A) Blood lead concentration (PbB) and (B) phosphatidylserine externalization on erythrocyte membranes of non-lead exposed (□) and lead exposed workers (■). Values are mean ± SD. *Significantly different (P < 0.001). - Highlights: • Erythrocytes of lead exposed workers showed higher PS

  9. Eryptosis in lead-exposed workers

    Energy Technology Data Exchange (ETDEWEB)

    Aguilar-Dorado, Itzel-Citlalli [Biochemistry Department, Centro de Investigación y Estudios Avanzados IPN, México, DF (Mexico); Hernández, Gerardo [Section of Methodology of Science, Centro de Investigación y Estudios Avanzados IPN, México, DF (Mexico); Quintanar-Escorza, Martha-Angelica [Faculty of Medicine, UJED, Durango, DGO (Mexico); Maldonado-Vega, María [CIATEC, León, GTO (Mexico); Rosas-Flores, Margarita [Biochemistry Department, Centro de Investigación y Estudios Avanzados IPN, México, DF (Mexico); Calderón-Salinas, José-Víctor, E-mail: jcalder@cinvestav.mx [Biochemistry Department, Centro de Investigación y Estudios Avanzados IPN, México, DF (Mexico)

    2014-12-01

    Eryptosis is a physiological phenomenon in which old and damaged erythrocytes are removed from circulation. Erythrocytes incubated with lead have exhibited major eryptosis. In the present work we found evidence of high levels of eryptosis in lead exposed workers possibly via oxidation. Blood samples were taken from 40 male workers exposed to lead (mean blood lead concentration 64.8 μg/dl) and non-exposed workers (4.2 μg/dl). The exposure to lead produced an intoxication characterized by 88.3% less δ-aminolevulinic acid dehydratase (δALAD) activity in lead exposed workers with respect to non-lead exposed workers. An increment of oxidation in lead exposed workers was characterized by 2.4 times higher thiobarbituric acid-reactive substance (TBARS) concentration and 32.8% lower reduced/oxidized glutathione (GSH/GSSG) ratio. Oxidative stress in erythrocytes of lead exposed workers is expressed in 192% higher free calcium concentration [Ca{sup 2+}]{sub i} and 1.6 times higher μ-calpain activity with respect to non-lead exposed workers. The adenosine triphosphate (ATP) concentration was not significantly different between the two worker groups. No externalization of phosphatidylserine (PS) was found in non-lead exposed workers (< 0.1%), but lead exposed workers showed 2.82% externalization. Lead intoxication induces eryptosis possibly through a molecular pathway that includes oxidation, depletion of reduced glutathione (GSH), increment of [Ca{sup 2+}], μ-calpain activation and externalization of PS in erythrocytes. Identifying molecular signals that induce eryptosis in lead intoxication is necessary to understand its physiopathology and chronic complications. - Graphical abstract: Fig. 1. (A) Blood lead concentration (PbB) and (B) phosphatidylserine externalization on erythrocyte membranes of non-lead exposed (□) and lead exposed workers (■). Values are mean ± SD. *Significantly different (P < 0.001). - Highlights: • Erythrocytes of lead exposed workers

  10. Lead shot from hunting as a source of lead in human blood

    International Nuclear Information System (INIS)

    Johansen, Poul; Pedersen, Henning Sloth; Asmund, Gert; Riget, Frank

    2006-01-01

    This study investigates the relationship between the intake of birds hunted with lead shot and the lead concentration in human blood. Fifty adult men from Nuuk, Greenland took part in the study. From September 2003 to June 2004 they regularly gave blood samples and recorded how many birds they ate. We found a clear relationship between the number of bird meals and blood lead and also a clear seasonal variation. The concentration was highest in mid-winter when bird consumption is at its highest. Blood lead was low (15 μg/L, mean concentration) among the participants reporting not eating birds. Among those reporting to eat birds regularly, blood lead was significantly higher, up to 128 μg/L (mean concentration). Concentrations depended on the frequency of bird meals: the more the bird meals, the higher the resulting blood lead. This clear relationship points to lead shot as the dominating lead source to people in Greenland. - Birds hunted with lead shot and consumed are a source of lead in human blood

  11. Lead shot from hunting as a source of lead in human blood

    Energy Technology Data Exchange (ETDEWEB)

    Johansen, Poul [National Environmental Research Institute, Frederiksborgvej 399, DK-4000 Roskilde (Denmark)]. E-mail: poj@dmu.dk; Pedersen, Henning Sloth [Primary Health Care Center, DK-3900 Nuuk (Greenland); Asmund, Gert [National Environmental Research Institute, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Riget, Frank [National Environmental Research Institute, Frederiksborgvej 399, DK-4000 Roskilde (Denmark)

    2006-07-15

    This study investigates the relationship between the intake of birds hunted with lead shot and the lead concentration in human blood. Fifty adult men from Nuuk, Greenland took part in the study. From September 2003 to June 2004 they regularly gave blood samples and recorded how many birds they ate. We found a clear relationship between the number of bird meals and blood lead and also a clear seasonal variation. The concentration was highest in mid-winter when bird consumption is at its highest. Blood lead was low (15 {mu}g/L, mean concentration) among the participants reporting not eating birds. Among those reporting to eat birds regularly, blood lead was significantly higher, up to 128 {mu}g/L (mean concentration). Concentrations depended on the frequency of bird meals: the more the bird meals, the higher the resulting blood lead. This clear relationship points to lead shot as the dominating lead source to people in Greenland. - Birds hunted with lead shot and consumed are a source of lead in human blood.

  12. The leaching of lead from lead-based paint in landfill environments.

    Science.gov (United States)

    Wadanambi, Lakmini; Dubey, Brajesh; Townsend, Timothy

    2008-08-30

    Lead leaching from lead-based paint (LBP) was examined using standardized laboratory protocols and tests with leachate from actual and simulated landfill environments. Two different LBP samples were tested; leaching solutions included leachates from three municipal solid waste (MSW) landfills and three construction and demolition (C&D) debris landfills. The toxicity characteristic leaching procedure (TCLP) and the synthetic precipitation leaching procedure (SPLP) were also performed. Lead concentrations were many times higher using the TCLP compared to the SPLP and the landfill leachates. No significant difference (alpha=0.05) was observed in leached lead concentrations from the MSW landfill and C&D debris landfill leachates. The impact of other building materials present in LBP debris on lead leaching was examined by testing mixtures of LBP (2%) and different building materials (98%; steel, wood, drywall, concrete). The type of substrate present impacted lead leaching results, with concrete demonstrating the most dramatic impact; the lowest lead concentrations were measured in the presence of concrete under both TCLP and SPLP extractions.

  13. SLAVIC LITERATURES IN DALMATIAN PERIODICALS IN THE PERIOD OF CROATIAN MODERNISM

    Directory of Open Access Journals (Sweden)

    Robert Bacalja

    2010-01-01

    Full Text Available The paper analyzes translations and mediatorial articles from the Slavic literature published in Dalmatian newspapers and periodicals which contribute most to mediation during the period of Croatian Modernism. While periodicals in Dalmatia traditionally mediates from the Roman literature, especially from the Italian, in the examined corpus can be seen the remarkable reception of Slavic literature, particularly Russian.. The paradigm of the most recognized culture and literature in non Slavic world is desirable identity basis of the Croatian literature as a part of a large Slavic stem from romanticism to modernism. Mediation of Slavic literatures is examined on the corpus of newspapers and periodicals published in Dubrovnik, Split and Zadar (Crvena Hrvatska, Srđ, Sloboda, Jedinstvo/Novo jedinstvo, Novi vijek, Narodni list, Smotra dalmatinska, Iskra, Glasnik Matice dalmatinske, Lovor, etc..

  14. Ferroelastic Fingerprints in Methylammonium Lead Iodide Perovskite

    KAUST Repository

    Hermes, Ilka M.

    2016-02-12

    Methylammonium lead iodide (MAPbI3) perovskite materials show an outstanding performance in photovoltaic devices. However, certain material properties, especially the possible ferroic behavior, remain unclear. We observed distinct nanoscale periodic domains in the piezoresponse of MAPbI3(Cl) grains. The structure and the orientation of these striped domains indicate ferroelasticity as their origin. By correlating vertical and lateral piezoresponse force microscopy experiments performed at different sample orientations with x-ray diffraction, the preferred domain orientation was suggested to be the a1-a2-phase. The observation of these ferroelastic fingerprints appears to strongly depend on the film texture and thus the preparation route. The formation of the ferroelastic twin domains could be induced by internal strain during the cubic-tetragonal phase transition.

  15. Autonomous Robot Control via Autonomy Levels (ARCAL)

    Science.gov (United States)

    2015-08-21

    same simulated objects. VRF includes a detailed graphical user interface (GUI) front end that subscribes to objects over HLA and renders them, along...forces.html 8. Gao, H., LI, Z., and Zhao, X., "The User -defined and Func- tion-strengthened for CGF of VR -Forces [J]." Computer Simulation, vol. 6...info Scout vehicle commands Scout vehicle Sensor measurements Mission vehicle Mission goals Operator interface Scout belief update Logistics

  16. Sub-Doppler cooling in reduced-period optical lattice geometries

    International Nuclear Information System (INIS)

    Berman, P.R.; Raithel, G.; Zhang, R.; Malinovsky, V.S.

    2005-01-01

    It is shown that sub-Doppler cooling occurs in an atom-field geometry that can lead to reduced-period optical lattices. Four optical fields are combined to produce a 'standing wave' Raman field that drives transitions between two ground state sublevels. In contrast to conventional Sisyphus cooling, sub-Doppler cooling to zero velocity occurs when all fields are polarized in the same direction. Solutions are obtained using both semiclassical and quantum Monte Carlo methods in the case of exact two-photon resonance. The connection of the results with conventional Sisyphus cooling is established using a dressed state basis

  17. The identification of lead ammunition as a source of lead exposure in First Nations: The use of lead isotope ratios

    International Nuclear Information System (INIS)

    Tsuji, Leonard J.S.; Wainman, Bruce C.; Martin, Ian D.; Sutherland, Celine; Weber, Jean-Philippe; Dumas, Pierre; Nieboer, Evert

    2008-01-01

    The use of lead shotshell to hunt water birds has been associated with lead-contamination in game meat. However, evidence illustrating that lead shotshell is a source of lead exposure in subsistence hunting groups cannot be deemed definitive. This study seeks to determine whether lead shotshell constitutes a source of lead exposure using lead isotope ratios. We examined stable lead isotope ratios for lichens, lead shotshell and bullets, and blood from residents of Fort Albany and Kashechewan First Nations, and the City of Hamilton, Ontario, Canada. Data were analyzed using ANOVA and regression analyses. ANOVA of isotope ratios for blood revealed significant differences with respect to location, but not sex. Hamilton differed from both Kashechewan and Fort Albany; however, the First Nations did not differ from each other. ANOVA of the isotope ratios for lead ammunition and lichens revealed no significant differences between lichen groups (north and south) and for the lead ammunition sources (pellets and bullets). A plot of 206 Pb/ 204 Pb and 206 Pb/ 207 Pb values illustrated that lichens and lead ammunition were distinct groupings and only the 95% confidence ellipse of the First Nations group overlapped that of lead ammunition. In addition, partial correlations between blood-lead levels (adjusted for age) and isotope ratios revealed significant (p 206 Pb/ 204 Pb and 206 Pb/ 207 Pb, and a significant negative correlation for 208 Pb/ 206 Pb, as predicted if leaded ammunition were the source of lead exposure. In conclusion, lead ammunition was identified as a source of lead exposure for First Nations people; however, the isotope ratios for lead shotshell pellets and bullets were indistinguishable. Thus, lead-contaminated meat from game harvested with lead bullets may also be contributing to the lead body burden

  18. Drinking Water Contamination Due To Lead-based Solder

    Science.gov (United States)

    Garcia, N.; Bartelt, E.; Cuff, K. E.

    2004-12-01

    The presence of lead in drinking water creates many health hazards. Exposure to lead-contaminated water can affect the brain, the central nervous system, blood cells, and kidneys, causing such problems as mental retardation, kidney disease, heart disease, stroke, and death. One way in which lead can contaminate our water supply is through the use of lead solder to join pipes. Lead solder was widely used in the past because of its ease of application as well as its low cost. Lead contamination in residential areas has previously been found to be a particularly serious problem in first-draw samples, of water that has sat stagnant in pipes overnight. To investigate the time-dependence of drinking water lead contamination, we analyzed samples taken hourly of water exposed to lead solder. While our preliminary data was insufficient to show more than a rough correlation between time of exposure and lead concentration over short periods (1-3 hours), we were able to confirm that overnight exposure of water to lead-based solder results in the presence high levels of lead. We also investigated other, external factors that previous research has indicated contribute to increased concentrations of lead. Our analysis of samples of lead-exposed water at various pH and temperatures suggests that these factors can be equally significant in terms of their contribution to elevated lead concentration levels. In particular, water that is slightly corrosive appears to severely impact the solubility of lead. As this type of water is common in much of the Northeast United States, the presence of lead-based solder in residential areas there is especially problematic. Although lead-based solder has been banned since the 1980s, it remains a serious concern, and a practical solution still requires further research.

  19. Two-period resource duopoly with endogenous intertemporal capacity constraints

    International Nuclear Information System (INIS)

    Berk, Istemi

    2014-01-01

    This paper analyzes the strategic firm behavior within the context of a two-period resource duopoly model in which firms face endogenous intertemporal capacity constraints. Firms are allowed to invest in capacity in between two periods in order to increase their initial endowment of exhaustible resource stocks. Using this setup, we nd that the equilibrium price weakly decreases over time. Moreover, asymmetric distribution of initial resource stocks leads to a significant change in equilibrium outcome, provided that firms do not have the same cost structure in capacity additions. It is also verified that if only one company is capable of investment in capacity, the market moves to a more concentrated structure in the second period.

  20. Two-period resource duopoly with endogenous intertemporal capacity constraints

    Energy Technology Data Exchange (ETDEWEB)

    Berk, Istemi

    2014-07-15

    This paper analyzes the strategic firm behavior within the context of a two-period resource duopoly model in which firms face endogenous intertemporal capacity constraints. Firms are allowed to invest in capacity in between two periods in order to increase their initial endowment of exhaustible resource stocks. Using this setup, we nd that the equilibrium price weakly decreases over time. Moreover, asymmetric distribution of initial resource stocks leads to a significant change in equilibrium outcome, provided that firms do not have the same cost structure in capacity additions. It is also verified that if only one company is capable of investment in capacity, the market moves to a more concentrated structure in the second period.

  1. Lead-elevated activity of xanthine oxidase in lead-exposed workers

    Directory of Open Access Journals (Sweden)

    Sławomir Kasperczyk

    2013-04-01

    Full Text Available Background: The aim of the present study was to explore the connection between lead toxicity and the activity of xanthine oxidase (XO. In addition, we indicated the uric acid (UA and creatinine levels and concentration of erythrocyte malondialdehyde (MDA to estimate oxidative stress intensity. Materials and Methods: The examined group consisted of 125 healthy male employees of zinc and lead works. The examined group was divided into tertiles according to blood lead levels. In the collected blood samples, concentrations of lead-exposure indices, UA, creatinine, and MDA as well as activity of XO were measured concomitantly. The control group consisted of 32 healthy male administrative workers who were exposed to lead only environmentally. Results: XO activity and MDA level were significantly elevated in all tertiles compared to the control group. Creatinine level was significantly elevated in the medium and high tertiles. However, the level of UA was significantly elevated in the high tertile, while in the low and medium tertile only a tendency toward higher values was observed. Conclusions: Occupational exposure to lead induces activity of XO. This induction may contribute to the observed simultaneously increased oxidative stress, measured as MDA level, and the increased level of UA. Med Pr 2013;64(2:175–180

  2. Will leaded young mallards take wing? Effects of a single lead shot ingestion on growth of juvenile game-farm Mallard ducks Anas platyrhynchos

    International Nuclear Information System (INIS)

    Plouzeau, Eric; Guillard, Olivier; Pineau, Alain; Billiald, Philippe; Berny, Philippe

    2011-01-01

    This study aims to monitor retention of a single ingested lead shot in young mallards, and to evaluate effect on growth in relation to lead shot size class during late wing growth and the first wing molt period (8 to 12 weeks old). Toxicological tests, radiography and biometric measurements were conducted on 51 juvenile Mallard ducks. Forty one of them were given per os a single lead shot in three different commercially available sizes: No. 2 (LS2), No. 4 (LS4) and No. 6 (LS6). Less than 20% of total lead shots were found on X-rays at Day 21 (D) and none remained at D28, with mean retention time in gizzard calculated 12.85 ± 1.34 days for all treated groups. Young ducks developed high blood lead levels for each LS treatment at D15 in males and females, the maximal values being for LS2 (297.00 ± 78.64 μg/100 mL and 483.14 ± 83.70 μg/100 mL, respectively (p < 0.001)). Zinc protoporphyrin (ZPP) levels increased at D15 with LS2 and LS4 in males and only with LS6 in females. Treated ducks developed no symptoms of plumbism except light diarrhea, and at D40, all mallards had survived. We found that LS2 pellets released more lead in gizzards and produced the highest levels of blood lead, suggesting that LS2 pellets are more likely to intoxicate mallards than smaller sizes. The biometric measurements performed showed no statistical difference in weight or bill and wing length between control and treated groups, a finding suggesting that absorption of a single lead shot by young Mallard ducks does not affect their development during the first wing molt period, and appears not to compromise the flight capacity of young (post-juvenile) mallards. However, younger mallards and/or effects on growth of exposure to more than a single-shot dose still need to be investigated. - Research highlights: → The mean lead shot retention time in the digestive tract is shorter than expected. → The lead intoxication at D15 and D30 is confirmed in all mallards. → Size-class no. 2 lead

  3. Will leaded young mallards take wing? Effects of a single lead shot ingestion on growth of juvenile game-farm Mallard ducks Anas platyrhynchos

    Energy Technology Data Exchange (ETDEWEB)

    Plouzeau, Eric, E-mail: biozones@orange.fr [Museum National d' Histoire Naturelle, USM505 Ecosystemes et interactions toxiques, 12 rue Buffon, CP39, Paris Cedex 05 (France); Guillard, Olivier, E-mail: o.guillard@chu-poitiers.fr [CHU Poitiers, Laboratoire de biochimie 86021 Poitiers (France); Pineau, Alain, E-mail: alain.pineau@univ-nantes.fr [Universite Nantes, Faculte de Pharmacie, Laboratoire de Toxicologie 44000 Nantes (France); Billiald, Philippe, E-mail: billiald@mnhn.fr [Museum National d' Histoire Naturelle, USM505 Ecosystemes et interactions toxiques, 12 rue Buffon, CP39, Paris Cedex 05 (France); Berny, Philippe, E-mail: p.berny@vetagro-sup.fr [Laboratoire de Toxicologie, Ecole Nationale Veterinaire de Lyon, BP 83, 69280 Marcy L' Etoile (France)

    2011-05-15

    This study aims to monitor retention of a single ingested lead shot in young mallards, and to evaluate effect on growth in relation to lead shot size class during late wing growth and the first wing molt period (8 to 12 weeks old). Toxicological tests, radiography and biometric measurements were conducted on 51 juvenile Mallard ducks. Forty one of them were given per os a single lead shot in three different commercially available sizes: No. 2 (LS2), No. 4 (LS4) and No. 6 (LS6). Less than 20% of total lead shots were found on X-rays at Day 21 (D) and none remained at D28, with mean retention time in gizzard calculated 12.85 {+-} 1.34 days for all treated groups. Young ducks developed high blood lead levels for each LS treatment at D15 in males and females, the maximal values being for LS2 (297.00 {+-} 78.64 {mu}g/100 mL and 483.14 {+-} 83.70 {mu}g/100 mL, respectively (p < 0.001)). Zinc protoporphyrin (ZPP) levels increased at D15 with LS2 and LS4 in males and only with LS6 in females. Treated ducks developed no symptoms of plumbism except light diarrhea, and at D40, all mallards had survived. We found that LS2 pellets released more lead in gizzards and produced the highest levels of blood lead, suggesting that LS2 pellets are more likely to intoxicate mallards than smaller sizes. The biometric measurements performed showed no statistical difference in weight or bill and wing length between control and treated groups, a finding suggesting that absorption of a single lead shot by young Mallard ducks does not affect their development during the first wing molt period, and appears not to compromise the flight capacity of young (post-juvenile) mallards. However, younger mallards and/or effects on growth of exposure to more than a single-shot dose still need to be investigated. - Research highlights: {yields} The mean lead shot retention time in the digestive tract is shorter than expected. {yields} The lead intoxication at D15 and D30 is confirmed in all mallards

  4. Design and Implementation of a Community Health Worker HIV Treatment and Prevention Intervention in an HIV Hot Spot Fishing Community in Rakai, Uganda.

    Science.gov (United States)

    Long, Amanda; Mbabali, Ismail; Hutton, Heidi E; Thomas, Alvin G; Bugos, Eva; Mulamba, Jeremiah; Amico, Kathy Rivet; Nalugoda, Fred; Gray, Ronald H; Wawer, Maria J; Nakigozi, Gertrude; Chang, Larry W

    Innovative approaches are needed to increase engagement in HIV treatment and prevention services, particularly in HIV hot spots. Here, we detail our design, training approach, and early implementation experiences of a community-based HIV intervention called "health scouts." The intervention, utilizing a novel, theory-based approach, trained 10 community residents in an HIV hot spot fishing community to use motivational interviewing strategies and a mobile phone-based counseling application. During the first 3 months, 771 residents (median 82/health scout, range 27-160) were counseled. A directly observed Motivational Interviewing Treatment Integrity scale-based evaluation found adequate performance (median score 20/25, range 11-23). The health scout intervention was feasible to implement in a high HIV-prevalence fishing community, and its impact on HIV care outcomes will be evaluated in an ongoing cluster randomized trial. If found to be effective, it may be an important strategy for responding to HIV in high-burden settings.

  5. On exponential stability and periodic solutions of CNNs with delays

    Science.gov (United States)

    Cao, Jinde

    2000-03-01

    In this Letter, the author analyses further problems of global exponential stability and the existence of periodic solutions of cellular neural networks with delays (DCNNs). Some simple and new sufficient conditions are given ensuring global exponential stability and the existence of periodic solutions of DCNNs by applying some new analysis techniques and constructing suitable Lyapunov functionals. These conditions have important leading significance in the design and applications of globally stable DCNNs and periodic oscillatory DCNNs and are weaker than those in the earlier works [Phys. Rev. E 60 (1999) 3244], [J. Comput. Syst. Sci. 59 (1999)].

  6. Development of bone-lead reference materials for validating in vivo XRF measurements

    International Nuclear Information System (INIS)

    Parsons, P.J.; Zong, Y.Y.; Matthews, M. R.

    1995-01-01

    A number of biological reference materials (RM) have been prepared in our laboratory specifically for validating analytical methods for the determination of Pb in biological matrices (e.g. blood, urine, liver, and bone). The RM's were developed using animal (goats and cows) that are routinely dosed with lead acetate to produce proficiency test samples for blood lead (and erythrocyte protoporphyrin). In cases where an animal becomes injured or infirm, the veterinarian in charge may recommend that the animal be euthanized. In such cases, samples of bone, brain, liver, and other tissues containing lead are removed at autopsy. Currently, we have collected bone samples from nine goats and one cow that were dosed with lead over periods ranging from 1 to 10 years. During the autopsy, the epiphyses (bone joints) are separated from each long bone. Skin, muscle, and other adhering tissues are dissected or scraped from each bone. Bone marrow is also removed. All bare bones are currently stored at -70 degrees C until analyses for Pb are conducted

  7. Surviving the Lead Reliability Engineer Role in High Unit Value Projects

    Science.gov (United States)

    Perez, Reinaldo J.

    2011-01-01

    A project with a very high unit value within a company is defined as a project where a) the project constitutes one of a kind (or two-of-a-kind) national asset type of project, b) very large cost, and c) a mission failure would be a very public event that will hurt the company's image. The Lead Reliability engineer in a high visibility project is by default involved in all phases of the project, from conceptual design to manufacture and testing. This paper explores a series of lessons learned, over a period of ten years of practical industrial experience by a Lead Reliability Engineer. We expand on the concepts outlined by these lessons learned via examples. The lessons learned are applicable to all industries.

  8. Superconductivity in nanostructured lead

    Science.gov (United States)

    Lungu, Anca; Bleiweiss, Michael; Amirzadeh, Jafar; Saygi, Salih; Dimofte, Andreea; Yin, Ming; Iqbal, Zafar; Datta, Timir

    2001-01-01

    Three-dimensional nanoscale structures of lead were fabricated by electrodeposition of pure lead into artificial porous opal. The size of the metallic regions was comparable to the superconducting coherence length of bulk lead. Tc as high as 7.36 K was observed, also d Tc/d H was 2.7 times smaller than in bulk lead. Many of the characteristics of these differ from bulk lead, a type I superconductor. Irreversibility line and magnetic relaxation rates ( S) were also studied. S( T) displayed two maxima, with a peak value about 10 times smaller than that of typical high- Tc superconductors.

  9. Field demonstration of age dependent increase in lead phytoextraction by Pelargonium cultivar

    Science.gov (United States)

    Shahid, Muhammad; Arshad, Muhammad; Pinelli, Eric; Alric, Alain; Kaemmerer, Michel; Pradere, Philippe; Dumat, Camille

    2013-04-01

    Unnecessary for living organisms, lead (Pb) is one of the major widespread toxic metals found in the environment with potential danger to human health and to ecosystems (Shahid et al. 2012). Lead is known to induce a broad range of toxic effects to living organism, including those that are morphological, physiological and biochemical in origin (Pourrut et al. 2011). A field study was carried out in the vicinity of Pb recycling plant near Toulouse-France, and contaminated by atmospheric fallouts to evaluate lead extraction and uptake efficiency of hyperaccumulater Attar of Roses Pelargonium cultivar. It was found that Attar of Roses has ability to accumulate (8644 mgPb/kg DW plant) and survive on highly contaminated acidic soil (39250 mg kg-1 of total Pb) without any morpho-phytotoxicity symptoms. Moreover Attar showed increased extraction of lead from bulk soil to rhizosphere through Pb mobilization and ultimately increased uptake by roots and translocation to shoots. The studied contaminated soil could be cleaned up in few years by planting hyperaccumulater Attar of Rose for longer time period. Under optimum fertlization, irrigation and use of natural or synthetic chelates (EDTA, LMOWA, humic substances etc.) along with old Attar of rose plants, time requires for complete remediation of contaminated site can be reduced to practically applicable time period. Moreover, the use of Pelargonium for remediation has several additional practical, esthetical and economic advantages. The extraction of value-added essential oils from harvested biomass could offset the cost of deploying phytoremediation and renders it as a viable approach for remediating highly contaminated soils, on large scale. Keywords: metal uptake, Pelargonium, phytoremediation, cultivar, soil-plant transfer and kinetic. References Pourrut, B., Shahid, M., Dumat, C., Winterton, P., Pinelli, E., 2011a. Lead uptake, toxicity and detoxification in plants. Rev. Environ. Contam. Toxicol. 213, 113-136. Shahid

  10. Changes in regional brain GFAP levels and behavioral functioning following subchronic lead acetate exposure in adult rats

    NARCIS (Netherlands)

    Berg, K.J. van den; Lammers, J.H.C.M.; Hoogendijk, E.M.G.; Kulig, B.M.

    1996-01-01

    Adult male WAG/Rij/MBL rats were dosed with lead acetate at 0, 4.0, 8.0 or 12.5 mg/kg, 5 days per week for 4 weeks. Animals were assessed prior to exposure, at the end of the 4-week exposure period and after a 2-week recovery period using a functional observational battery (FOB) and motor activity

  11. Lead poisoning in dogs

    International Nuclear Information System (INIS)

    Zook, B.C.; Carpenter, J.L.; Leeds, E.B.

    1969-01-01

    Lead poisoning was diagnosed and studied in 60 dogs. It was found that lead poisoning is a common disease of young dogs, especially in the summer and fall, and is related to their chewing and eating habits resulting in the ingestion of paint, linoleum, or other lead-containing materials. The signs were characterized by gastrointestinal dysfunction (colic, vomiting, and diarrhea) and nervous disorders (convulsions, hysteria, nervousness, behavioral changes). The blood findings, which the authors consider nearly pathognomonic, consisted of numerous stippled and immature (especially nucleated) erythrocytes in the absence of severe anemia. Protein and casts were frequently found in the urine. Radiography sometimes revealed lead-containing particles in the gastro-intestinal tract, and lead lines were occasionally detected in the metaphysis of long bones in immature dogs. Treatment with calcium ethylenediamine-tetraacetic acid resulted in rapid and often dramatic recoveries in nearly all instances. Removal of lead from the gastrointestinal tract and treatment to relieve pronounced central nervous disorders was sometimes necessary. 40 references, 6 figures, 7 tables

  12. Non-linear vibrational modes in biomolecules: A periodic orbits description

    International Nuclear Information System (INIS)

    Kampanarakis, Alexandros; Farantos, Stavros C.; Daskalakis, Vangelis; Varotsis, Constantinos

    2012-01-01

    Graphical abstract: Vibrational frequency shifts in Fe IV = O species of the active site of cytochrome c oxidase are attributed to changes in the surrounding Coulomb field. Periodic orbits analysis assists to find the most anharmonic modes in model biomolecules. Highlights: ► Periodic orbits are extended to multidimensional potentials of biomolecules. ► Highly anharmonic vibrational modes and center-saddle bifurcations are detected. ► Vibrational frequencies shifts in Oxoferryl species of CcO are observed. - Abstract: The vibrational harmonic normal modes of a molecule, which are valid at energies close to an equilibrium point (a minimum, maximum or saddle of the potential energy surface), are extended by periodic orbits to high energies where anharmonicity and coupling of the degrees of freedom are significant. In this way the assignment of the spectra, and thus the extraction of dynamics in highly excited molecules, can be obtained. New vibrational modes emanating from bifurcations of periodic orbits and long living localized trajectories signal the birth and localization of new quantum states. In this article we review and further study non-linear vibrational modes for model biomolecules such as alanine dipeptide and the active site in the oxoferryl oxidation state of the enzyme cytochrome c oxidase. We locate periodic orbits which exhibit high anhamonicity and lead to center-saddle bifurcations. These modes are associated to an isomerization process in alanine dipeptide and to frequency shifts in the oxoferryl observed by modifying the Coulomb field around the Imidazole–Fe IV = O species.

  13. Dosimetric evaluation of indigenously developed non-lead bilayered radiation protective aprons

    International Nuclear Information System (INIS)

    Senthilkumar, S.

    2018-01-01

    Radiation shielding garments are commonly used to protect medical patients and radiation workers from X-radiation exposure during diagnostic imaging in hospitals. Originally, protective aprons consisted of lead-impregnated vinyl with a shielding equivalent given in millimeters of lead. All contained up to 2 mm of lead. While lead has long been used to shield patients from X-rays, its toxicity poses a health threat if the protective apron containing the metal wear out or the lead gets damaged. However, lead garments must be treated as hazardous waste for disposal and are heavy, causing back strain and other orthopedic problems for those who must wear them for long periods of time. The main purpose of this work was to indigenously develop light weight non lead based bilayered radiation protective aprons and evaluate dosimetrically with different combination of fabricated non lead materials and commercially available lead based aprons

  14. Eryptosis in lead-exposed workers.

    Science.gov (United States)

    Aguilar-Dorado, Itzel-Citlalli; Hernández, Gerardo; Quintanar-Escorza, Martha-Angelica; Maldonado-Vega, María; Rosas-Flores, Margarita; Calderón-Salinas, José-Víctor

    2014-12-01

    Eryptosis is a physiological phenomenon in which old and damaged erythrocytes are removed from circulation. Erythrocytes incubated with lead have exhibited major eryptosis. In the present work we found evidence of high levels of eryptosis in lead exposed workers possibly via oxidation. Blood samples were taken from 40 male workers exposed to lead (mean blood lead concentration 64.8μg/dl) and non-exposed workers (4.2μg/dl). The exposure to lead produced an intoxication characterized by 88.3% less δ-aminolevulinic acid dehydratase (δALAD) activity in lead exposed workers with respect to non-lead exposed workers. An increment of oxidation in lead exposed workers was characterized by 2.4 times higher thiobarbituric acid-reactive substance (TBARS) concentration and 32.8% lower reduced/oxidized glutathione (GSH/GSSG) ratio. Oxidative stress in erythrocytes of lead exposed workers is expressed in 192% higher free calcium concentration [Ca(2+)]i and 1.6 times higher μ-calpain activity with respect to non-lead exposed workers. The adenosine triphosphate (ATP) concentration was not significantly different between the two worker groups. No externalization of phosphatidylserine (PS) was found in non-lead exposed workers (lead exposed workers showed 2.82% externalization. Lead intoxication induces eryptosis possibly through a molecular pathway that includes oxidation, depletion of reduced glutathione (GSH), increment of [Ca(2+)], μ-calpain activation and externalization of PS in erythrocytes. Identifying molecular signals that induce eryptosis in lead intoxication is necessary to understand its physiopathology and chronic complications. Copyright © 2014 Elsevier Inc. All rights reserved.

  15. European observatory of the energy markets. Period 2004 and winter 2004/05

    International Nuclear Information System (INIS)

    2005-01-01

    The report underlines for the studied period many tendencies which could compromise the supplying safety: the prices increase of the primary energies, the production margins decrease during the peak period, the poor progression of the frontier exchange, and a weak of a long dated vision leading to the investments deficit in the infrastructures

  16. Deaths: Leading Causes for 2012.

    Science.gov (United States)

    Heron, Melonie

    2015-08-31

    This report presents final 2012 data on the 10 leading causes of death in the United States by age, sex, race, and Hispanic origin. Leading causes of infant, neonatal, and postneonatal death are also presented. This report supplements "Deaths: Final Data for 2012," the National Center for Health Statistics' annual report of final mortality statistics. Data in this report are based on information from all death certificates filed in the 50 states and the District of Columbia in 2012. Causes of death classified by the International Classification of Diseases, Tenth Revision (ICD-10) are ranked according to the number of deaths assigned to rankable causes. Cause-of-death statistics are based on the underlying cause of death. In 2012, the 10 leading causes of death were, in rank order: Diseases of heart; Malignant neoplasms; Chronic lower respiratory diseases; Cerebrovascular diseases; Accidents (unintentional injuries); Alzheimer's disease; Diabetes mellitus; Influenza and pneumonia; Nephritis, nephrotic syndrome and nephrosis; and Intentional self-harm (suicide). These causes accounted for 74% of all deaths occurring in the United States. Differences in the rankings are evident by age, sex, race, and Hispanic origin. Leading causes of infant death for 2012 were, in rank order: Congenital malformations, deformations and chromosomal abnormalities; Disorders related to short gestation and low birth weight, not elsewhere classified; Sudden infant death syndrome; Newborn affected by maternal complications of pregnancy; Accidents (unintentional injuries); Newborn affected by complications of placenta, cord and membranes; Bacterial sepsis of newborn; Respiratory distress of newborn; Diseases of the circulatory system; and Neonatal hemorrhage. Important variations in the leading causes of infant death are noted for the neonatal and postneonatal periods.

  17. Recommended Format for the Periodic Table of the Elements.

    Science.gov (United States)

    Loening, K. L.

    1984-01-01

    Presents a new, recommended format for the periodic table which does not use the letters A and B to designate subgroups of elements. Also describes events leading to the adoption of this recommendation. (JM)

  18. 75 FR 4451 - Notification of United States Mint 2010 Commemorative Coin Pricing

    Science.gov (United States)

    2010-01-27

    ... Dollar and the 2010 Boy Scouts of America Centennial Silver Dollar Programs. Public Laws 110-227 and 110... Scouts of America Centennial Silver Dollar Commemorative Coins, respectively. [[Page 4452

  19. Finding hidden periodic signals in time series - an application to stock prices

    Science.gov (United States)

    O'Shea, Michael

    2014-03-01

    Data in the form of time series appear in many areas of science. In cases where the periodicity is apparent and the only other contribution to the time series is stochastic in origin, the data can be `folded' to improve signal to noise and this has been done for light curves of variable stars with the folding resulting in a cleaner light curve signal. Stock index prices versus time are classic examples of time series. Repeating patterns have been claimed by many workers and include unusually large returns on small-cap stocks during the month of January, and small returns on the Dow Jones Industrial average (DJIA) in the months June through September compared to the rest of the year. Such observations imply that these prices have a periodic component. We investigate this for the DJIA. If such a component exists it is hidden in a large non-periodic variation and a large stochastic variation. We show how to extract this periodic component and for the first time reveal its yearly (averaged) shape. This periodic component leads directly to the `Sell in May and buy at Halloween' adage. We also drill down and show that this yearly variation emerges from approximately half of the underlying stocks making up the DJIA index.

  20. Impact of lead tolerant plant growth promoting rhizobacteria on growth, physiology, antioxidant activities, yield and lead content in sunflower in lead contaminated soil.

    Science.gov (United States)

    Saleem, Muhammad; Asghar, Hafiz Naeem; Zahir, Zahir Ahmad; Shahid, Muhammad

    2018-03-01

    Present study was conducted to evaluate the effect of lead tolerant plant growth promoting rhizobacteria (LTPGPR) on growth, physiology, yield, antioxidant activities and lead uptake in sunflower in soil contaminated with lead under pot conditions. Three pre-characterized LTPGP strains (S2 (Pseudomonas gessardii strain BLP141), S5 (Pseudomonas fluorescens A506) and S10 (Pseudomonas fluorescens strain LMG 2189)) were used to inoculate sunflower growing in soil contaminated with different levels (300, 600 and 900 mg kg -1 ) of lead by using lead nitrate salt as source of lead. Treatments were arranged according to completely randomized design with factorial arrangements. At harvesting, data regarding growth attributes (root shoot length, root shoot fresh and dry weights), yield per plant, physiological attributes (Chlorophyll 'a', 'b' and carotenoids content), antioxidant activities (Ascorbate peroxidase, catalase, superoxide dismutase and glutathione reductase), proline and malanodialdehyde content, and lead content in root, shoot and achenes of sunflower were recorded. Data were analysed by standard statistical procedures. Results showed that lead contamination reduced the plants growth, physiology and yield at all levels of lead stress. But application of LTPGPR in soil contaminated with lead improved plant growth, physiology, yield, and antioxidant activities, proline, and reduced the malanodialdehyde content (that is reduced by the application of different strains in lead contamination) of sunflower as compared to plants grown in soil without inoculation. Inoculation also promoted the uptake of lead in root, shoots and reduced the uptake of lead in achenes of plants as compared to plants in lead contamination without inoculation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Leading-edge vortex shedding from rotating wings

    Energy Technology Data Exchange (ETDEWEB)

    Kolomenskiy, Dmitry [Centre de Recherches Mathématiques (CRM), Department of Mathematics and Statistics, McGill University, 805 Sherbrooke W., Montreal, QC H3A 0B9 (Canada); Elimelech, Yossef [Faculty of Aerospace Engineering, Technion-Israel Institute of Technology, Haifa 32000 (Israel); Schneider, Kai, E-mail: dkolom@gmail.com [M2P2–CNRS, Université d' Aix-Marseille, 39, rue Frédéric Joliot-Curie, F-13453 Marseille Cedex 13 (France)

    2014-06-01

    This paper presents a numerical investigation of the leading-edge vortices generated by rotating triangular wings at Reynolds number Re = 250. A series of three-dimensional numerical simulations have been carried out using a Fourier pseudo-spectral method with volume penalization. The transition from stable attachment of the leading-edge vortex to periodic vortex shedding is explored, as a function of the wing aspect ratio and the angle of attack. It is found that, in a stable configuration, the spanwise flow in the recirculation bubble past the wing is due to the centrifugal force, incompressibility and viscous stresses. For the flow outside of the bubble, an inviscid model of spanwise flow is presented. (papers)

  2. Lead identification in soil surrounding a used lead acid battery smelter area in Banten, Indonesia

    International Nuclear Information System (INIS)

    Adventini, N; Santoso, M; Lestiani, D D; Syahfitri, W Y N; Rixson, L

    2017-01-01

    A used lead acid battery smelter generates particulates containing lead that can contaminate the surrounding environment area. Lead is a heavy metal which is harmful to health if it enters the human body through soil, air, or water. An identification of lead in soil samples surrounding formal and informal used lead acid battery smelters area in Banten, Indonesia using EDXRF has been carried out. The EDXRF accuracy and precision evaluated from marine sediment IAEA 457 gave a good agreement to the certified value. A number of 16 soil samples from formal and informal areas and 2 soil samples from control area were taken from surface and subsurface soils. The highest lead concentrations from both lead smelter were approximately 9 folds and 11 folds higher than the reference and control samples. The assessment of lead contamination in soils described in C f index was in category: moderately and strongly polluted by lead for formal and informal lead smelter. Daily lead intake of children in this study from all sites had exceeded the recommended dietary allowance. The HI values for adults and children living near both lead smelter areas were greater than the value of safety threshold 1. This study finding confirmed that there is a potential health risk for inhabitants surrounding the used lead acid battery smelter areas in Banten, Indonesia. (paper)

  3. Bioaccumulation of lead nitrate in freshwater crayfish (Astacus leptodactylus) tissues under aquaculture conditions.

    Science.gov (United States)

    Naghshbandi, N; Zare, S; Heidari, R; Soleimani Palcheglu, S

    2007-09-15

    The aim of this research was to evaluate the amount of lead in the tissue of Astacus leptodactylus especially in their muscle which the consumed part of their body. In this study the crayfish was exposed to intermediate concentration of lead nitrate (500 microg L(-1)) for periods up to 3 weeks. In the first, second and third weeks bioaccumulation in various tissues was under investigation. The data of toxicological analysis obtained by the method of atomic absorption revealed that the levels of bioaccumulation of metal are different in various tissues of this crayfish. The accumulation of the lead in gills was the highest and in muscles was lowest degree. The amount of heavy metals in the tissues of crayfish was as follow. Gills>exoskeleton>hepatopancreas (digestive glands)>digestive tract>green gland>testis and ovary>muscles.

  4. Periodic oscillations in linear continuous media coupled with nonlinear discrete systems

    International Nuclear Information System (INIS)

    Lupini, R.

    1998-01-01

    A general derivation of partial differential equations with boundary conditions in the form of ordinary differential equations is obtained using the principle of stationary action for a Lagrangian function composed of continuous plus discrete parts in interaction across the boundaries of a 1-dimensional medium. This approach leads directly to the theorem of energy conservation. For linear continuous medium, homogeneous Dirichlet condition at one boundary, and nonlinear oscillator at the other boundary, the entire differential problem reduces to a nonlinear differential-difference equation of neutral type and of the second order. The lag parameter is τ = l/c, where c is the phase speed, l the length of the continuum. The Author investigate the problem of the occurrence of periodic solutions of period integer multiple of the lag (super harmonic solutions) in the case of zero inertia of the boundary system. The problem for such oscillations is shown to reduce to systems of ordinary differential equations with matching conditions in a phase space of lower dimensionality: Phase-plane techniques are used to determine solutions of period 4τ, 8τ and 6τ

  5. Book Reviews in Periodicals.

    Science.gov (United States)

    Ettelt, Harold J.

    All recent issues of periodicals found which contain indexed book reviews are listed in this compilation from Drake Memorial Library at the New York State University at Brockport. The periodicals are listed by 29 subject headings in this informal guide designed to be used at Drake Library. The number of reviews in the periodical in a recent year…

  6. Lead isotope ratios in artists' lead white: a progress report

    Energy Technology Data Exchange (ETDEWEB)

    Keisch, B; Callahan, R C [Carnegie-Mellon Univ., Pittsburgh, Pa. (USA)

    1976-07-01

    The lead isotope ratios in over four hundred samples of lead white have been determined. The samples represent various geographical sources and dates from the thirteenth century to the present. A new method for organizing this large volume of data is described which helps with the visualization of temporal and geographic patterns. A number of interesting relationships between lead isotope ratio and date or source are shown to exist. Some examples of successful applications of this methodology are described.

  7. Evaluation of Oxidative Stress in Combination Therapy with D-penicillamine and N-Acetylcysteine (NAC in Lead Poisoning in Opium Addicts

    Directory of Open Access Journals (Sweden)

    Saeedeh Shojaeepour

    2017-12-01

    Full Text Available Background: N-acetylcysteine (NAC is a putative antioxidant and has gained attention as a promising agent for chelating heavy metals including lead. Considering the animal studies results, we hypothesized that adding NAC to the treatment regimen may improve the success of treatment with lead chelators. Methods: A total of 46 patients who were lead-poisoned opioid addicts were divided into two groups randomly and treated with d-penicillamine (DP, 1g/day in four equal divided doses and NAC+DP (1 g/day + 150 mg/kg/day. The efficacy of treatment was evaluated by hospitalization period. Meanwhile, the oxidative stress parameters including lipid peroxidation, protein carbonyl, total antioxidant capacity (TAC, glutathione concentration and super oxide dismutase (SOD activity were determined on admission and discharge and compared with healthy normal controls. Results: Hospitalization period was not different between the two groups. Treatment with DP and DP+NAC significantly decreased oxidative stress in patients. On the discharge day, the SOD activity and TAC were significantly higher in DP+NAC group in comparison with the DP group. Conclusion: Although NAC recovers antioxidant capacity, the advantages of NAC in improvement of DP efficacy in lead poisoning is questionable. Further studies with larger sample size and combination with other chelators are recommended.

  8. Changes in body weight and pulse

    DEFF Research Database (Denmark)

    Seimon, R V; Espinoza, D; Finer, N

    2015-01-01

    BACKGROUND/OBJECTIVES: The Sibutramine Cardiovascular OUTcomes (SCOUT) trial showed a significantly increased relative risk of nonfatal cardiovascular events, but not mortality, in overweight and obese subjects receiving long-term sibutramine treatment with diet and exercise. We examined the rela......BACKGROUND/OBJECTIVES: The Sibutramine Cardiovascular OUTcomes (SCOUT) trial showed a significantly increased relative risk of nonfatal cardiovascular events, but not mortality, in overweight and obese subjects receiving long-term sibutramine treatment with diet and exercise. We examined...... the relationship between early changes (both increases and decreases) in pulse rate, and the impact of these changes on subsequent cardiovascular outcome events in both the placebo and sibutramine groups. SUBJECTS/METHODS: 9804 males and females, aged ⩾55 years, with a body mass index of 27-45 kg m(-)(2) were...... included in this current subanalysis of the SCOUT trial. Subjects were required to have a history of cardiovascular disease and/or type 2 diabetes mellitus with at least one cardiovascular risk factor, to assess cardiovascular outcomes. The primary outcome event (POE) was a composite of nonfatal myocardial...

  9. The performance of a soluble lead-acid flow battery and its comparison to a static lead-acid battery

    International Nuclear Information System (INIS)

    Zhang, C.P.; Sharkh, S.M.; Li, X.; Walsh, F.C.; Zhang, C.N.; Jiang, J.C.

    2011-01-01

    Highlights: → We compared the electrochemical characteristics of two types of the batteries. → SLAFB shows as good performance as SLAB under the same current density. → The cycle life of two batteries is strongly influenced by the depth of discharge. → The cycle life of SLAFB can be extended by treatment with hydrogen peroxide. - Abstract: The electrochemistry of static lead-acid and soluble lead-acid flow batteries is summarised and the differences between the two batteries are highlighted. A general comparison of the performance of an unoptimised soluble lead-acid flow laboratory cell and a commercial lead-acid battery during charge and discharge is reported. The influence of the depth of discharge on cycle life for both batteries is also considered. The flow battery was found to have a better charge efficiency than the static one, but the cells were found to have comparable energy efficiencies. The self-discharge characteristics of the soluble lead-acid battery were also measured and compared to reported values for a commercial static battery. Some self-discharge of the soluble lead-acid flow battery is observed during prolonged periods on open-circuit but the battery could recover its normal performance after a single charge-discharge cycle.

  10. Hydrocarbon Degradation and Lead Solubility in a Soil Polluted with Lead and Used Motor Oil Treated by Composting and Phytoremediation.

    Science.gov (United States)

    Escobar-Alvarado, L F; Vaca-Mier, M; López, R; Rojas-Valencia, M N

    2018-02-01

    Used lubricant oils and metals can be common soil pollutants in abandoned sites. When soil is contaminated with various hazardous wastes, the efficiency of biological treatments could be affected. The purpose of this work was to investigate the effect of combining phytoremediation and composting on the efficiency of hydrocarbon degradation and lead solubility in a soil contaminated with 31,823 mg/kg of total petroleum hydrocarbon (TPH) from used motor oil and 8260 mg/kg of lead. Mexican cactus (Opuntia ficus indica) and yard trimmings were added in the composting process, and lucerne (Medicago sativa) was used in the phytoremediation process. After a 9 week composting process, only 13% of the initial TPH concentration was removed. The following 20 week phytoremediation process removed 48% of TPH. The highest TPH degradation percentage (66%), was observed in the experiment with phytoremediation only. This work demonstrates sustainable technologies, such as biological treatments, represent low-cost options for remediation; however, they are not frequently used because they require long periods of time for success.

  11. Lead isotope ratios in artists' lead white: a progress report

    International Nuclear Information System (INIS)

    Keisch, B.; Callahan, R.C.

    1976-01-01

    The lead isotope ratios in over four hundred samples of lead white have been determined. The samples represent various geographical sources and dates from the thirteenth century to the present. A new method for organizing this large volume of data is described which helps with the visualization of temporal and geographic patterns. A number of interesting relationships between lead isotope ratio and date or source are shown to exist. Some examples of successful applications of this methodology are described. (author)

  12. Lead toxicity on hematological parameters in workers with occupational exposure to lead

    International Nuclear Information System (INIS)

    Dursun, N.; Koese, K.

    1998-01-01

    The effects of lead on hematological parameters were studied in lead exposed male workers occupied for 17.84+-4.22 years in a metal powder producing factory in Kayseri, Turkey and control male workers in same city. Blood lead and plasma zinc levels were measured by Atomic Absorption Spectrophotometry (AAS) and hematological parameters by Culture Counter S. The lead exposure workers had higher lead levels (13.81+- 9.21 mug/dl) as compared to control subjects (2.37+-0.10 mug/dl). No difference was observed in the plasma zinc levels of both groups. As indices of lead exposure, red blood cell (RBC) counts, hemoglobin (Hb), and hematocrit (Hct) values significantly decreased. Mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular haemoglobin concentration (MCHC) significantly increased except MCV. There was also an increase in MCV, but it was not significant. (author)

  13. Vector boson and Charmonium production in proton-lead and lead-lead collisions with ATLAS at the LHC

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00241320; The ATLAS collaboration

    2016-01-01

    Electroweak bosons do not interact strongly with the dense and hot medium formed in nuclear collisions, and thus should be sensitive to the nuclear modification of parton distribution functions (nPDFs). The in-medium modification of heavy charmonium states plays an important role in studying the hot and dense medium. The ATLAS detector, optimized to search for new physics in proton-proton collisions, is well equipped to measure Z and W bosons as well as quarkonium in the high occupancy environment produced in heavy ion collisions. Results from the ATLAS experiment on W and Z boson yields as a function of centrality, transverse momentum and rapidity, in lead-lead and proton-lead collisions are presented. Quarkonium results from proton-lead collisions are also presented.

  14. Lead levels in new enamel household paints from Asia, Africa and South America.

    Science.gov (United States)

    Clark, C Scott; Rampal, Krishna G; Thuppil, Venkatesh; Roda, Sandy M; Succop, Paul; Menrath, William; Chen, Chin K; Adebamowo, Eugenious O; Agbede, Oluwole A; Sridhar, Mynepalli K C; Adebamowo, Clement A; Zakaria, Yehia; El-Safty, Amal; Shinde, Rana M; Yu, Jiefei

    2009-10-01

    In 2006 a report on the analysis for lead in 80 new residential paints from four countries in Asia revealed high levels in three of the countries (China, India and Malaysia) and low levels in a fourth country (Singapore) where a lead in paint regulation was enforced. The authors warned of the possible export of lead-painted consumer products to the United States and other countries and the dangers the lead paint represented to children in the countries where it was available for purchase. The need for a worldwide ban on the use of lead in paints was emphasized to prevent an increase in exposure and disease from this very preventable environmental source. Since the earlier paper almost 300 additional new paint samples have been collected from the four initial countries plus 8 additional countries, three from Asia, three from Africa and two from South America. During the intervening time period two million toys and other items imported into the United States were recalled because the lead content exceeded the United States standard. High lead paints were detected in all 12 countries. The average lead concentration by country ranged from 6988 (Singapore) to 31,960ppm (Ecuador). One multinational company sold high lead paint in one country through January 2007 but sold low lead paint later in 2007 indicating that a major change to cease adding lead to their paints had occurred. However, the finding that almost one-third of the samples would meet the new United States standard for new paint of 90ppm, suggests that the technology is already available in at least 11 of the 12 countries to produce low lead enamel paints for domestic use. The need remains urgent to establish effective worldwide controls to prevent the needless poisoning of millions of children from this preventable exposure.

  15. Deaths: Leading Causes for 2011.

    Science.gov (United States)

    Heron, Melonie

    2015-07-27

    This report presents final 2011 data on the 10 leading causes of death in the United States by age, sex, race, and Hispanic origin. Leading causes of infant, neonatal, and postneonatal death are also presented. This report supplements ‘‘Deaths: Final Data for 2011,’’ the National Center for Health Statistics’ annual report of final mortality statistics. Data in this report are based on information from all death certificates filed in the 50 states and the District of Columbia in 2011. Causes of death classified by the International Classification of Diseases, 10th Revision (ICD–10) are ranked according to the number of deaths assigned to rankable causes. Cause-of-death statistics are based on the underlying cause of death. In 2011, the 10 leading causes of death were, in rank order: Diseases of heart; Malignant neoplasms; Chronic lower respiratory diseases; Cerebrovascular diseases; Accidents (unintentional injuries); Alzheimer’s disease; Diabetes mellitus; Influenza and pneumonia; Nephritis, nephrotic syndrome and nephrosis; and Intentional self-harm (suicide). They accounted for 74% of all deaths occurring in the United States. Differences in the rankings are evident by age, sex, race, and Hispanic origin. Leading causes of infant death for 2011 were, in rank order: Congenital malformations, deformations and chromosomal abnormalities; Disorders related to short gestation and low birth weight, not elsewhere classified; Sudden infant death syndrome; Newborn affected by maternal complications of pregnancy; Accidents (unintentional injuries); Newborn affected by complications of placenta, cord and membranes; Bacterial sepsis of newborn; Respiratory distress of newborn; Diseases of the circulatory system; and Neonatal hemorrhage. Important variations in the leading causes of infant death are noted for the neonatal and postneonatal periods. All material appearing in this report is in the public domain and may be reproduced or copied without permission

  16. Deaths: Leading Causes for 2015.

    Science.gov (United States)

    Heron, Melonie

    2017-11-01

    Objectives-This report presents final 2015 data on the 10 leading causes of death in the United States by age, sex, race, and Hispanic origin. Leading causes of infant, neonatal, and postneonatal death are also presented. This report supplements "Deaths: Final Data for 2015," the National Center for Health Statistics' annual report of final mortality statistics. Methods-Data in this report are based on information from all death certificates filed in the 50 states and the District of Columbia in 2015. Causes of death classified by the International Classification of Diseases, Tenth Revision (ICD-10) are ranked according to the number of deaths assigned to rankable causes. Cause-of-death statistics are based on the underlying cause of death. Results-In 2015, the 10 leading causes of death were, in rank order: Diseases of heart; Malignant neoplasms; Chronic lower respiratory diseases; Accidents (unintentional injuries); Cerebrovascular diseases; Alzheimer's disease; Diabetes mellitus; Influenza and pneumonia; Nephritis, nephrotic syndrome and nephrosis; and Intentional self-harm (suicide). They accounted for 74% of all deaths occurring in the United States. Differences in the rankings are evident by age, sex, race, and Hispanic origin. Leading causes of infant death for 2015 were, in rank order: Congenital malformations, deformations and chromosomal abnormalities; Disorders related to short gestation and low birth weight, not elsewhere classified; Sudden infant death syndrome; Newborn affected by maternal complications of pregnancy; Accidents (unintentional injuries); Newborn affected by complications of placenta, cord and membranes; Bacterial sepsis of newborn; Respiratory distress of newborn; Diseases of the circulatory system; and Neonatal hemorrhage. Important variations in the leading causes of infant death are noted for the neonatal and postneonatal periods. All material appearing in this report is in the public domain and may be reproduced or copied without

  17. Deaths: leading causes for 2010.

    Science.gov (United States)

    Heron, Melonie

    2013-12-20

    This report presents final 2010 data on the 10 leading causes of death in the United States by age, sex, race, and Hispanic origin. Leading causes of infant, neonatal, and postneonatal death are also presented. This report supplements the Division of Vital Statistics' annual report of final mortality statistics. Data in this report are based on information from all death certificates filed in the 50 states and the District of Columbia in 2010. Causes of death classified by the International Classification of Diseases, Tenth Revision (ICD-10) are ranked according to the number of deaths assigned to rankable causes. Cause-of-death statistics are based on the underlying cause of death. In 2010, the 10 leading causes of death were, in rank order: Diseases of heart; Malignant neoplasms; Chronic lower respiratory diseases; Cerebrovascular diseases; Accidents (unintentional injuries); Alzheimer's disease; Diabetes mellitus; Nephritis, nephrotic syndrome and nephrosis; Influenza and pneumonia; and Intentional self-harm (suicide). These 10 causes accounted for 75% of all deaths occurring in the United States. Differences in the rankings are evident by age, sex, race, and Hispanic origin. Leading causes of infant death for 2010 were, in rank order: Congenital malformations, deformations and chromosomal abnormalities; Disorders related to short gestation and low birth weight, not elsewhere classified; Sudden infant death syndrome; Newborn affected by maternal complications of pregnancy; Accidents (unintentional injuries); Newborn affected by complications of placenta, cord and membranes; Bacterial sepsis of newborn; Respiratory distress of newborn; Diseases of the circulatory system; and Necrotizing enterocolitis of newborn. Important variations in the leading causes of infant death are noted for the neonatal and post-neonatal periods. All material appearing in this report is in the public domain and may be reproduced or copied without permission; citation as to source

  18. Deaths: Leading Causes for 2013.

    Science.gov (United States)

    Heron, Melonie

    2016-02-16

    This report presents final 2013 data on the 10 leading causes of death in the United States by age, sex, race, and Hispanic origin. Leading causes of infant, neonatal, and postneonatal death are also presented. This report supplements "Deaths: Final Data for 2013," the National Center for Health Statistics’ annual report of final mortality statistics. Data in this report are based on information from all death certificates filed in the 50 states and the District of Columbia in 2013. Causes of death classified by the International Classification of Diseases, Tenth Revision (ICD–10) are ranked according to the number of deaths assigned to rankable causes. Cause-of-death statistics are based on the underlying cause of death. In 2013, the 10 leading causes of death were, in rank order: Diseases of heart; Malignant neoplasms; Chronic lower respiratory diseases; Accidents (unintentional injuries); Cerebrovascular diseases; Alzheimer’s disease; Diabetes mellitus; Influenza and pneumonia; Nephritis, nephrotic syndrome and nephrosis; and Intentional self-harm (suicide). They accounted for 74% of all deaths occurring in the United States. Differences in the rankings are evident by age, sex, race, and Hispanic origin. Leading causes of infant death for 2013 were, in rank order: Congenital malformations, deformations and chromosomal abnormalities; Disorders related to short gestation and low birth weight, not elsewhere classified; Newborn affected by maternal complications of pregnancy; Sudden infant death syndrome; Accidents (unintentional injuries); Newborn affected by complications of placenta, cord and membranes; Bacterial sepsis of newborn; Respiratory distress of newborn; Diseases of the circulatory system; and Neonatal hemorrhage. Important variations in the leading causes of infant death are noted for the neonatal and postneonatal periods. All material appearing in this report is in the public domain and may be reproduced or copied without permission; citation as

  19. The influence of global benchmark oil prices on the regional oil spot market in multi-period evolution

    International Nuclear Information System (INIS)

    Jiang, Meihui; An, Haizhong; Jia, Xiaoliang; Sun, Xiaoqi

    2017-01-01

    Crude benchmark oil prices play a crucial role in energy policy and investment management. Previous research confined itself to studying the static, uncertain, short- or long-term relationship between global benchmark oil prices, ignoring the time-varying, quantitative, dynamic nature of the relationship during various stages of oil price volatility. This paper proposes a novel approach combining grey relation analysis, optimization wavelet analysis, and Bayesian network modeling to explore the multi-period evolution of the dynamic relationship between global benchmark oil prices and regional oil spot price. We analyze the evolution of the most significant decision-making risk periods, as well as the combined strategy-making reference oil prices and the corresponding periods during various stages of volatility. Furthermore, we determine that the network evolution of the quantitative lead/lag relationship between different influences of global benchmark oil prices shows a multi-period evolution phenomenon. For policy makers and market investors, our combined model can provide decision-making periods with the lowest expected risk and decision-making target reference oil prices and corresponding weights for strategy adjustment and market arbitrage. This study provides further information regarding period weights of target reference oil prices, facilitating efforts to perform multi-agent energy policy and intertemporal market arbitrage. - Highlights: • Multi-period evolution of the influence of different oil prices is discovered. • We combined grey relation analysis, optimization wavelet and Bayesian network. • The intensity of volatility, synchronization, and lead/lag effects are analyzed. • The target reference oil prices and corresponding period weights are determined.

  20. Experimental lead poisoning in chickens

    Energy Technology Data Exchange (ETDEWEB)

    Silven, L.

    1967-01-01

    Poisoning of water fowl due to the intake of lead shot is not rare in the USA. In order to study this kind of poisoning more closely domestic fowl were given varying amounts of lead shot and lead powder. This treatment did not provoke any symptoms of poisoning. Chemical analyses of different organs, muscles, skeleton and eggs yielded low lead values. It is concluded that the low toxicity of lead administered as lead shot to the domestic fowl is due to a low absorption rate from the gastro-intestinal tract.

  1. MAGNETIC ROSSBY WAVES IN THE SOLAR TACHOCLINE AND RIEGER-TYPE PERIODICITIES

    International Nuclear Information System (INIS)

    Zaqarashvili, Teimuraz V.; Carbonell, Marc; Oliver, Ramon; Ballester, Jose Luis

    2010-01-01

    Apart from the eleven-year solar cycle, another periodicity around 155-160 days was discovered during solar cycle 21 in high-energy solar flares, and its presence in sunspot areas and strong magnetic flux has been also reported. This periodicity has an elusive and enigmatic character, since it usually appears only near the maxima of solar cycles, and seems to be related with a periodic emergence of strong magnetic flux at the solar surface. Therefore, it is probably connected with the tachocline, a thin layer located near the base of the solar convection zone, where a strong dynamo magnetic field is stored. We study the dynamics of Rossby waves in the tachocline in the presence of a toroidal magnetic field and latitudinal differential rotation. Our analysis shows that the magnetic Rossby waves are generally unstable and that the growth rates are sensitive to the magnetic field strength and to the latitudinal differential rotation parameters. Variation of the differential rotation and the magnetic field strength throughout the solar cycle enhance the growth rate of a particular harmonic in the upper part of the tachocline around the maximum of the solar cycle. This harmonic is symmetric with respect to the equator and has a period of 155-160 days. A rapid increase of the wave amplitude could give rise to a magnetic flux emergence leading to observed periodicities in solar activity indicators related to magnetic flux.

  2. Lead isotopes in soils near five historic American lead smelters and refineries

    International Nuclear Information System (INIS)

    Rabinowitz, Michael B.

    2005-01-01

    This survey of soil lead in the vicinity of old industrial sites examines how the stable isotope patterns vary among the sites according to the sources of the lead ore processed at each site. Lead smelters and refineries, which closed down decades ago, are the basis of this investigation. Samples were taken from near five old factory sites in Collinsville and Alton (Illinois), Ponderay (Idaho), East Chicago (Indiana) and Omaha (Nebraska). Historical records were searched for accounts of the sources of the lead. Lead concentrations were measured by atomic absorption flame spectrophotometry, and stable isotopic analysis was done by plasma ionization mass spectrometry. At every site visited, remnants of the old factories, in terms of soil lead pollution, could be found. In spite of potential complications of varying smelter feedstock sourced from mines of different geological age, it was possible to match the isotopic patterns in the soils with the documented sources of the ores. The Collinsville and Alton sites resembled Missouri lead. The Ponderay value was higher than major Bunker Hill, Idaho deposits, but closer to the minor, nearby Oreille County, Washington ores. Mostly Utah ore was used in East Chicago. The Omaha soil reflects lead from Mexico, Colorado and Montana

  3. Corrosion behavior of steels in flowing lead-bismuth under abnormal conditions

    International Nuclear Information System (INIS)

    Doubkova, A.; Di Gabriele, F.; Brabec, P.; Keilova, E.

    2008-01-01

    The project IP EUROTRANS, domain DEMETRA, is primary focused on the study of the technology of the interaction between steels and heavy liquid metals. The characterization of the metal response to sudden changes, simulating accidental conditions in liquid lead-bismuth eutectic was carried out. This paper reports the results of two hot-spot simulations with two different oxygen concentrations (10 -8 wt%, 10 -6 wt%). Each experiment was divided in two main periods: the initial, long period at the standard operating temperature 550 deg. C; the second, short period, at higher temperature, 650 deg. C. The damage that occurs on the austenitic steel AISI 316L and the ferritic-martensitic steel T91 was investigated. The amount of damage for both steels was higher at lower oxygen contents and the short, hot spot simulation, markedly affected the T91. At higher oxygen content the amount of damage decreased. A few, localized pits, were observed; however, there was no visible increment in the amount of damage after the hot spot simulation

  4. 32 CFR 728.81 - Other civilians.

    Science.gov (United States)

    2010-07-01

    ... meets. (v) Members of Little League teams and Youth Conservation groups. (vi) Boy Scouts and Girl Scouts... United Nations) or by a voluntary nonprofit-relief agency registered with and approved by the Advisory...

  5. Quantification of atmospheric lead emissions from 70 years of leaded petrol consumption in Australia

    Science.gov (United States)

    Kristensen, Louise Jane

    2015-06-01

    Lead is a persistent pollutant and the subject of many environmental studies, yet, in Australia, the extent of atmospheric lead emissions from the use of leaded petrol is unquantified. This paper details the first comprehensive account of leaded petrol sales and its lead concentrations over the 70 years of use in Australia. The resulting atmospheric lead emissions are calculated to provide the most complete understanding of the volume of lead released to the Australian continent from the consumption of leaded petrol. Atmospheric emissions of lead to the entire Australian continent from leaded petrol are calculated to total 240,510 tonnes over seven decades of use, peaking at 7869 tonnes in 1974. Total emissions for individual states and territories range from 1745 to 67,893 tonnes, with New South Wales responsible for the largest emissions. The effect of regulations on allowable concentrations of tetraethyl-lead additives are observed in the reduction of lead emissions in New South Wales and Victoria. The consequences to human health and the environment of leaded petrol consumption in Australia's populous cities are examined against historical air quality data and blood lead levels.

  6. Racism and Acceptance: a Clash Between Aunt Alexandra and Scout in To Kill a Mockingbird%歧视还是接受:析《杀死一只知更鸟》中Aunt Alexandra和Scout体现出来的种族歧视文化冲突(英文)

    Institute of Scientific and Technical Information of China (English)

    王颖慧

    2011-01-01

    《杀死一只知更鸟》是一部描述美国种族歧视的作品。通过对小说中两个女性人物Aunt Alexan-dra和Scout的比较,可以更清晰的体现出美国内战以后人们对黑人的态度转变:从极度的歧视到理解性的接受。%To Kill a Mocking Bird is a work which successfully described racism in America. This paper makes a comparative analysis of two female characters: Aunt Alexandra and Scout. The comparisons of these two female characters illustrate the great change from racism to acceptance towards the blacks in America after the Civil War.

  7. Blood Lead Levels in Children and Environmental Lead Contamination in Miami Inner City, Florida

    Directory of Open Access Journals (Sweden)

    Theophile Niyonsenga

    2006-09-01

    Full Text Available Studies have shown that the environmental conditions of the home are important predictors of health, especially in low-income communities. Understanding the relationship between the environment and health is crucial in the management of certain diseases. One health outcome related to the home environment among urban, minority, and low-income children is childhood lead poisoning. The most common sources of lead exposure for children are lead paint in older, dilapidated housing and contaminated dust and soil produced by accumulated residue of leaded gasoline. Blood lead levels (BLL as low as 10 μg/dL in children are associated with impaired cognitive function, behavior difficulties, and reduced intelligence. Recently, it is suggested that the standard for intervention be lowered to BLL of 5 μg /dl. The objectives of our report were to assess the prevalence of lead poisoning among children under six years of age and to quantify and test the correlations between BLL in children and lead exposure levels in their environment. This cross-sectional analysis was restricted to 75 children under six years of age who lived in 6 zip code areas of inner city Miami. These locations exhibited unacceptably high levels of lead dust and soil in areas where children live and play. Using the 5 μg/dL as the cutoff point, the prevalence of lead poisoning among the study sample was 13.33%. The study revealed that lead levels in floor dust and window sill samples were positively and significantly correlated with BLL among children (p < 0.05. However, the correlations between BLL and the soil, air, and water samples were not significant. Based on this pilot study, a more comprehensive environmental study in surrounding inner city areas is warranted. Parental education on proper housecleaning techniques may also benefit those living in the high lead-exposed communities of inner city Miami.

  8. Health risk factors in lead polluted environment causing isthemic health disease

    International Nuclear Information System (INIS)

    Khnwal, S.; Rahman, K.U.

    2008-01-01

    Faisalabad is third most populous and industrial city, known as Manchester of Pakistan. Most of the people working in the industries of this city are exposed to highly polluted and toxic environment. Lead is a natural metal found in the environment and its contamination exceeds the range of normal limits by human activities causing a lot of health hazardous. An effort is made to assess the association of anemia and cholesterol with the development IHD among industrial workers who are exposed to the lead polluted environment. For this purpose the study was conducted during a period of one year (2006-7) and the respondents were the patients from industrial area coming to the hospitals visiting at DHQ Hospital Faisalabad. Only those patients were selected for this study who were diagnosed with clinical symptoms of lead toxicity. The demographic features of the respondents regarding their age, gender, marital status, family size, education, income, duration on job, working place and nature of work were considered. The data of this study was categorical nature and this measures the association among exposure to the environment with lead toxicity and causative risk factors i.e., cholesterol level, Hb level (anemia) causing ischemic heart disease (IHD) were studied. (author)

  9. Lead Poisoning in Wild Birds

    Science.gov (United States)

    Lahner, Lesanna L.; Franson, J. Christian

    2009-01-01

    Lead in its various forms has been used for thousands of years, originally in cooking utensils and glazes and more recently in many industrial and commercial applications. However, lead is a potent, potentially deadly toxin that damages many organs in the body and can affect all animals, including humans. By the mid 1990s, lead had been removed from many products in the United States, such as paint and fuel, but it is still commonly used in ammunition for hunting upland game birds, small mammals, and large game animals, as well as in fishing tackle. Wild birds, such as mourning doves, bald eagles, California condors, and loons, can die from the ingestion of one lead shot, bullet fragment, or sinker. According to a recent study on loon mortality, nearly half of adult loons found sick or dead during the breeding season in New England were diagnosed with confirmed or suspected lead poisoning from ingestion of lead fishing weights. Recent regulations in some states have restricted the use of lead ammunition on certain upland game hunting areas, as well as lead fishing tackle in areas frequented by common loons and trumpeter swans. A variety of alternatives to lead are available for use in hunting, shooting sports, and fishing activities.

  10. Identification of flood-rich and flood-poor periods in flood series

    Science.gov (United States)

    Mediero, Luis; Santillán, David; Garrote, Luis

    2015-04-01

    Recently, a general concern about non-stationarity of flood series has arisen, as changes in catchment response can be driven by several factors, such as climatic and land-use changes. Several studies to detect trends in flood series at either national or trans-national scales have been conducted. Trends are usually detected by the Mann-Kendall test. However, the results of this test depend on the starting and ending year of the series, which can lead to different results in terms of the period considered. The results can be conditioned to flood-poor and flood-rich periods located at the beginning or end of the series. A methodology to identify statistically significant flood-rich and flood-poor periods is developed, based on the comparison between the expected sampling variability of floods when stationarity is assumed and the observed variability of floods in a given series. The methodology is applied to a set of long series of annual maximum floods, peaks over threshold and counts of annual occurrences in peaks over threshold series observed in Spain in the period 1942-2009. Mediero et al. (2014) found a general decreasing trend in flood series in some parts of Spain that could be caused by a flood-rich period observed in 1950-1970, placed at the beginning of the flood series. The results of this study support the findings of Mediero et al. (2014), as a flood-rich period in 1950-1970 was identified in most of the selected sites. References: Mediero, L., Santillán, D., Garrote, L., Granados, A. Detection and attribution of trends in magnitude, frequency and timing of floods in Spain, Journal of Hydrology, 517, 1072-1088, 2014.

  11. The relationship between environmental lead and blood lead in children : a study in environmental epidemiology

    NARCIS (Netherlands)

    Brunekreef, B.

    1985-01-01

    This study deals with the relationship between environmental lead and blood lead in children.
    Chapter 1 provides a summary of the environmental health aspects of lead. The occurrence of lead in the environment and in man is described; children are discussed as a population at

  12. Lead- or Lead-bismuth-cooled fast reactors

    International Nuclear Information System (INIS)

    Bouchter, J.C.; Courouau, J.L.; Dufour, P.; Guidez, J.; Latge, C.; Martinelli, L.; Renault, C.; Rimpault, G.

    2014-01-01

    Lead-cooled fast reactors are one of the 6 concepts retained for the 4. generation of nuclear reactors. So far no lead-cooled reactors have existed in the world except lead-bismuth-cooled reactors in soviet submarines. Some problems linked to the use of the lead-bismuth eutectic appeared but were satisfactorily solved by a more rigorous monitoring of the chemistry of the lead-bismuth coolant. Lead presents various advantages as a coolant: no reactivity with water and the air,a high boiling temperature and low contamination when irradiated. The main asset of the lead-bismuth alloy is the drop of the fusion temperature from 327 C degrees to 125 C degrees. The main drawback of using lead (or lead-bismuth) is its high corrosiveness with metals like iron, chromium and nickel. The high corrosiveness of the coolant implies low flow velocities which means a bigger core and consequently a bigger reactor containment. Different research programs in the world (in Europe, Russia and the USA) are reviewed in the article but it appears that the development of this type of reactor requires technological breakthroughs concerning materials and the resistance to corrosion. Furthermore the concept of lead-cooled reactors seems to be associated to a range of low output power because of the compromise between the size of the reactor and its resistance to earthquakes. (A.C.)

  13. Performance of Lead-Free versus Lead-Based Hunting Ammunition in Ballistic Soap

    Science.gov (United States)

    Gremse, Felix; Krone, Oliver; Thamm, Mirko; Kiessling, Fabian; Tolba, René Hany; Rieger, Siegfried; Gremse, Carl

    2014-01-01

    Background Lead-free hunting bullets are an alternative to lead-containing bullets which cause health risks for humans and endangered scavenging raptors through lead ingestion. However, doubts concerning the effectiveness of lead-free hunting bullets hinder the wide-spread acceptance in the hunting and wildlife management community. Methods We performed terminal ballistic experiments under standardized conditions with ballistic soap as surrogate for game animal tissue to characterize dimensionally stable, partially fragmenting, and deforming lead-free bullets and one commonly used lead-containing bullet. The permanent cavities created in soap blocks are used as a measure for the potential wound damage. The soap blocks were imaged using computed tomography to assess the volume and shape of the cavity and the number of fragments. Shots were performed at different impact speeds, covering a realistic shooting range. Using 3D image segmentation, cavity volume, metal fragment count, deflection angle, and depth of maximum damage were determined. Shots were repeated to investigate the reproducibility of ballistic soap experiments. Results All bullets showed an increasing cavity volume with increasing deposited energy. The dimensionally stable and fragmenting lead-free bullets achieved a constant conversion ratio while the deforming copper and lead-containing bullets showed a ratio, which increases linearly with the total deposited energy. The lead-containing bullet created hundreds of fragments and significantly more fragments than the lead-free bullets. The deflection angle was significantly higher for the dimensionally stable bullet due to its tumbling behavior and was similarly low for the other bullets. The deforming bullets achieved higher reproducibility than the fragmenting and dimensionally stable bullets. Conclusion The deforming lead-free bullet closely resembled the deforming lead-containing bullet in terms of energy conversion, deflection angle, cavity shape

  14. Performance of lead-free versus lead-based hunting ammunition in ballistic soap.

    Directory of Open Access Journals (Sweden)

    Felix Gremse

    Full Text Available BACKGROUND: Lead-free hunting bullets are an alternative to lead-containing bullets which cause health risks for humans and endangered scavenging raptors through lead ingestion. However, doubts concerning the effectiveness of lead-free hunting bullets hinder the wide-spread acceptance in the hunting and wildlife management community. METHODS: We performed terminal ballistic experiments under standardized conditions with ballistic soap as surrogate for game animal tissue to characterize dimensionally stable, partially fragmenting, and deforming lead-free bullets and one commonly used lead-containing bullet. The permanent cavities created in soap blocks are used as a measure for the potential wound damage. The soap blocks were imaged using computed tomography to assess the volume and shape of the cavity and the number of fragments. Shots were performed at different impact speeds, covering a realistic shooting range. Using 3D image segmentation, cavity volume, metal fragment count, deflection angle, and depth of maximum damage were determined. Shots were repeated to investigate the reproducibility of ballistic soap experiments. RESULTS: All bullets showed an increasing cavity volume with increasing deposited energy. The dimensionally stable and fragmenting lead-free bullets achieved a constant conversion ratio while the deforming copper and lead-containing bullets showed a ratio, which increases linearly with the total deposited energy. The lead-containing bullet created hundreds of fragments and significantly more fragments than the lead-free bullets. The deflection angle was significantly higher for the dimensionally stable bullet due to its tumbling behavior and was similarly low for the other bullets. The deforming bullets achieved higher reproducibility than the fragmenting and dimensionally stable bullets. CONCLUSION: The deforming lead-free bullet closely resembled the deforming lead-containing bullet in terms of energy conversion

  15. Pacemaker lead fracture without an increase in lead impedance caused by cardiac fibroma

    Directory of Open Access Journals (Sweden)

    Daisuke Sato

    2013-12-01

    Full Text Available We report the case of a 64-year-old man who had a permanent pacemaker with a unipolar silicone electrode positioned in the right ventricle in 1989 for sinus node dysfunction. On a routine checkup in June 2011, a 28-mm-diameter mass was discovered, which appeared to adhere to the tricuspid valve and the ventricular lead. The size of the mass did not change for the next 6 months, and the lead impedance was maintained at around 500–600 Ω. Because pacing failure was observed in January 2012, he underwent an urgent pacemaker check; however, the lead impedance was found not to have increased greatly (689 Ω. Nevertheless, the pacemaker lead was noted to be fractured at the tricuspid level. His echocardiogram showed new severe tricuspid regurgitation and a floating mass around the lead. We extracted the fractured lead, enucleated the tumor, replaced the tricuspid valve, and placed an epicardial lead. Macroscopic examination revealed that the tumor surrounded the fractured lead and covered the stump. Pathological examination revealed that the tumor was composed of fibrous connective tissue. We presumed that electric current continued to flow through the stump of the fractured unipolar lead to the generator, and this might have caused the limited increase in lead impedance.

  16. Epidemiology of Dysglycemia in Pregnant Oklahoma American Indian Women.

    Science.gov (United States)

    Azar, Madona; Stoner, Julie A; Dao, Hanh Dung; Stephens, Lancer; Goodman, Jean R; Maynard, John; Lyons, Timothy J

    2015-08-01

    Minority communities are disproportionately affected by diabetes, and minority women are at an increased risk for glucose intolerance (dysglycemia) during pregnancy. In pregnant American Indian women, the objectives of the study were to use current criteria to estimate the prevalence of first-trimester (Tr1) dysglycemia and second-trimester (Tr2) incidence of gestational diabetes mellitus (GDM) and to explore new candidate measures and identify associated clinical factors. This was a prospective cohort study. In Tr1 we performed a 75-g, 2-hour oral glucose tolerance test (OGTT) and glycated hemoglobin (HbA1c) to determine the following: fasting insulin; homeostasis model assessment of insulin resistance; serum 1,5-anhydroglucitol; noninvasive skin autofluorescence (SCOUT). We defined dysglycemia by American Diabetes Association and Endocrine Society criteria and as HbA1c of 5.7% or greater. In Tr2 in an available subset, we performed a repeat OGTT and SCOUT. Pregnant American Indian women (n = 244 at Tr1; n = 114 at Tr2) participated in the study. The prevalence of dysglycemia at Tr1 and incidence of GDM at Tr2 were measured. At Tr1, one woman had overt diabetes; 36 (15%) had impaired glucose tolerance (American Diabetes Association criteria and/or abnormal HbA1c) and 59 (24%) had GDM-Tr1 (Endocrine Society criteria). Overall, 74 (30%) had some form of dysglycemia. Associated factors were body mass index, hypertension, waist/hip circumferences, SCOUT score, fasting insulin, and homeostasis model assessment of insulin resistance. At Tr2, 114 of the Tr1 cohort underwent a repeat OGTT and SCOUT, and 26 (23%) had GDM. GDM-Tr2 was associated with increased SCOUT scores (P = .029) and Tr1 body mass index, waist/hip circumferences, diastolic blood pressure, fasting insulin, and triglyceride levels. Overall, dysglycemia at Tr1 and/or Tr2 affected 38% of the women. Dysglycemia at some point during pregnancy was common among American Indian women. It was associated with

  17. Toxic effects of lead and nickel nitrate on rat liver chromatin components.

    Science.gov (United States)

    Rabbani-Chadegani Iii, Azra; Fani, Nesa; Abdossamadi, Sayeh; Shahmir, Nosrat

    2011-01-01

    The biological activity of heavy metals is related to their physicochemical interaction with biological receptors. In the present study, the effect of low concentrations of nickel nitrate and lead nitrate (lead nitrate to chromatin compared to nickel nitrate. Also, the binding affinity of lead nitrate to histone proteins free in solution was higher than nickel. On the basis of the results, it is concluded that lead reacts with chromatin components even at very low concentrations and induce chromatin aggregation through histone-DNA cross-links. Whereas, nickel nitrate is less effective on chromatin at low concentrations, suggesting higher toxicity of lead nitrate on chromatin compared to nickel. Copyright © 2010 Wiley Periodicals, Inc.

  18. Aphid alarm pheromone as a cue for ants to locate aphid partners.

    Directory of Open Access Journals (Sweden)

    François J Verheggen

    Full Text Available The mutualistic relationships that occur between myrmecophilous aphids and ants are based on the rich food supply that honeydew represents for ants and on the protection they provide against aphid natural enemies. While aphid predators and parasitoids actively forage for oviposition sites by using aphid semiochemicals, scouts of aphid-tending ant species would also benefit from locating honeydew resources by orienting toward aphid pheromone sources. The present study aims to provide additional information on the use of Aphis fabae alarm pheromone, i.e. (E-β-farnesene (EβF, by ant scouts. The perception and behavioral impact of EβF on Lasius niger were investigated using electroantennography and two bio-assays measuring their attraction and orientation towards aphid semiochemicals. Pronounced electrical depolarizations were observed from L. niger scout antennae to stimulations of A. fabae alarm pheromone, while other sesquiterpenes elicited weak or no responses. L. niger scouts were significantly attracted toward EβF in a four-arm olfactometer, as well as in an two-choice bioassay. These laboratory results suggest for the first time that low amounts of aphid alarm pheromone can be used by L. niger scouts as a cue indicating the presence of aphid colonies and could therefore mediate the aphid-ant partnership in the field.

  19. Lead Intoxication in Children in Birmingham

    Science.gov (United States)

    Betts, P. R.; Astley, R.; Raine, D. N.

    1973-01-01

    Of 38 children investigated between 1966 and 1971 who had a blood lead concentration greater than 37 μg/100 ml eight had encephalopathy and one died; all these eight had a blood lead concentration of 99 μg/100 ml or above. Blood lead levels are related to haemoglobin concentrations and anaemia is common in children with blood lead concentrations of 37-60 μg/100 ml, levels previously accepted as harmless. Children with blood lead concentrations greater than 60 μg/100 ml show radiological evidence of lead intoxication, and treatment for this should be considered when blood lead concentration exceeds 37 μg/100 ml. Children presenting with unexplained encephalopathy should be radiographed for evidence of lead intoxication. ImagesFIG. 2FIG. 1 PMID:4691065

  20. Lead isotope ratios in Japanese galena ores and archaeological objects

    International Nuclear Information System (INIS)

    Yamasaki, Kazuo; Murozumi, Masayo; Nakamura, Seiji; Hinata, Makoto; Yuasa, Mitsuaki.

    1978-01-01

    Lead isotope ratios 206 Pb/ 204 Pb, 207 Pb/ 204 Pb, 208 Pb/ 204 Pb, 207 Pb/ 206 Pb and 208 Pb/ 206 Pb in Japanese galena ores and archaeological bronze objects were determined by a Hitachi RMU-6 mass spectrometer using a rhenium single filament as a surface ionization device. Basic experimental conditions including detection limit, fractionation effect, memory effect, etc. were examined, and the accuracy of determination was checked using the CIT shelf standard No. 1. Archaeological bronze objects were dissolved in nitric acid and lead was extracted by the dithizone method using specially purified reagents in a so-called clean laboratory. When 0.5 μg lead was loaded on the rhenium filament with phosphoric acid and silica gel as stabilizers, an ion current of 10 -13 -- 10 -15 A due to Pb + was obtained and maintained stable for several hours. Coefficients of variation found for the isotope ratios 207 Pb/ 206 Pb and 208 Pb/ 206 Pb were 0.1 -- 0.5%. Lead isotope ratios are given for 17 Japanese galena ores and for archaeological bronze objects such as bronze bells, halberds (Yayoi period), Horyuji pagoda spire (7th century), and Northern Sung coins (11th century). A close resemblance of the isotope ratios was found between Japanese galena ores and some Japanese bronze objects of the 7th century, suggesting the use of the former as raw materials of the latter. (auth.)

  1. Involving Lead Users in Innovation

    DEFF Research Database (Denmark)

    Brem, Alexander; Bilgram, Volker; Gutstein, Adele

    2018-01-01

    Research on the lead user method has been conducted for more than thirty years and has shown that the method is more likely to generate breakthrough innovation than traditional market research tools. Based on a systematic literature review, this paper shows a detailed view on the broad variety...... of research on lead user characteristics, lead user processes, lead user identification and application, and success factors. The main challenge of the lead user method as identified in literature is the resource issue regarding time, manpower, and costs. Also, internal acceptance and the processing...... of the method have been spotted in literature, as well as the intellectual property protection issue. From the starting point of the initial lead user method process introduced by Lüthje and Herstatt (2004), results are integrated into a revisited view on the lead user method process. In addition, concrete...

  2. Periodic or chaotic bursting dynamics via delayed pitchfork bifurcation in a slow-varying controlled system

    Science.gov (United States)

    Yu, Yue; Zhang, Zhengdi; Han, Xiujing

    2018-03-01

    In this work, we aim to demonstrate the novel routes to periodic and chaotic bursting, i.e., the different bursting dynamics via delayed pitchfork bifurcations around stable attractors, in the classical controlled Lü system. First, by computing the corresponding characteristic polynomial, we determine where some critical values about bifurcation behaviors appear in the Lü system. Moreover, the transition mechanism among different stable attractors has been introduced including homoclinic-type connections or chaotic attractors. Secondly, taking advantage of the above analytical results, we carry out a study of the mechanism for bursting dynamics in the Lü system with slowly periodic variation of certain control parameter. A distinct delayed supercritical pitchfork bifurcation behavior can be discussed when the control item passes through bifurcation points periodically. This delayed dynamical behavior may terminate at different parameter areas, which leads to different spiking modes around different stable attractors (equilibriums, limit cycles, or chaotic attractors). In particular, the chaotic attractor may appear by Shilnikov connections or chaos boundary crisis, which leads to the occurrence of impressive chaotic bursting oscillations. Our findings enrich the study of bursting dynamics and deepen the understanding of some similar sorts of delayed bursting phenomena. Finally, some numerical simulations are included to illustrate the validity of our study.

  3. Directory of National Recreation Organizations.

    Science.gov (United States)

    Exceptional Parent, 1991

    1991-01-01

    Thirty national recreation organizations serving individuals with disabilities are listed, along with addresses and telephone numbers. Sample recreational activities covered include Boy Scouts and Girls Scouts, various wheelchair sports, skiing, golfing, and horticultural therapy. (JDD)

  4. Impact of a hospital-level intervention to reduce heart disease overreporting on leading causes of death.

    Science.gov (United States)

    Al-Samarrai, Teeb; Madsen, Ann; Zimmerman, Regina; Maduro, Gil; Li, Wenhui; Greene, Carolyn; Begier, Elizabeth

    2013-05-16

    The quality of cause-of-death reporting on death certificates affects the usefulness of vital statistics for public health action. Heart disease deaths are overreported in the United States. We evaluated the impact of an intervention to reduce heart disease overreporting on other leading causes of death. A multicomponent intervention comprising training and communication with hospital staff was implemented during July through December 2009 at 8 New York City hospitals reporting excessive heart disease deaths. We compared crude, age-adjusted, and race/ethnicity-adjusted proportions of leading, underlying causes of death reported during death certification by intervention and nonintervention hospitals during preintervention (January-June 2009) and postintervention (January-June 2010) periods. We also examined trends in leading causes of death for 2000 through 2010. At intervention hospitals, heart disease deaths declined by 54% postintervention; other leading causes of death (ie, malignant neoplasms, influenza and pneumonia, cerebrovascular disease, and chronic lower respiratory diseases) increased by 48% to 232%. Leading causes of death at nonintervention hospitals changed by 6% or less. In the preintervention period, differences in leading causes of death between intervention and nonintervention hospitals persisted after controlling for race/ethnicity and age; in the postintervention period, age accounted for most differences observed between intervention and nonintervention hospitals. Postintervention, malignant neoplasms became the leading cause of premature death (ie, deaths among patients aged 35-74 y) at intervention hospitals. A hospital-level intervention to reduce heart disease overreporting led to substantial changes to other leading causes of death, changing the leading cause of premature death. Heart disease overreporting is likely obscuring the true levels of cause-specific mortality.

  5. Periodic gaits for the CMU Ambler

    Science.gov (United States)

    Dwivedi, Suren N.; Mahalingam, Swaminathan

    1992-02-01

    The configuration of the Carnegie-Mellon University Ambler, a six-legged autonomous walking vehicle for exploring Mars, enables the recovery of a trailing leg past the leading leg to reduce the energy expenditure in terrain interactions. In this article, gaits developed for this unprecedented configuration are described. A stability criterion has been developed that ensures stability of the vehicle in the event of failure of any one of the supporting legs. Periodic gaits developed for the Ambler utilize the Ambler's unique abilities and continuously satisfy the stability criterion.

  6. The Use of the Lead and Line by Early Navigators in the North Sea?

    Directory of Open Access Journals (Sweden)

    John Kemp

    2014-12-01

    Full Text Available This paper draws attention to the lack of information as to how early North Sea sailors navigated, particularly during the one thousand year period that followed Roman times. The lead and line was the only navigational aid available for most of this period, but there is little recorded as to whether it was used simply for ensuring a ship or boat had enough water to proceed or whether, together with the knowledge it provided of the nature of the sea bed, it was used as a more positive position fixing device. The author would appreciate any information relating to navigation techniques used during this period.

  7. Levels of blood lead in Griffon vultures from a Wildlife Rehabilitation Center in Spain.

    Science.gov (United States)

    González, Fernando; López, Irene; Suarez, Laura; Moraleda, Virginia; Rodríguez, Casilda

    2017-09-01

    Lead is considered a highly toxic contaminant with important impacts to bird wildlife. Griffon vultures (Gyps fulvus) are a sensitive indicator of the level of environmental contamination due to their position at the top of the food chain and their dependence on human activities. The aim of this study was to assess susceptibility to lead intoxication in Griffon vultures admitted to Wildlife Rehabilitation Centers (WRC), measuring blood lead levels and determining if blood lead concentrations are related to clinical signs, hematological, biochemical or radiographic findings. Also, the influence of age, gender, body condition, season and primary cause of admission were evaluated. This study was realized in all Griffon vultures admitted during a period of one year in the Rehabilitation Center GREFA. Blood lead levels are measured by using anodic stripping voltammetry. In Griffon vultures, we observed that 26% of the analyzed birds presented lead levels above 20µg/dL with 74% below 20µg/dL ([Pb] lead according to sex, season of admission to the center and body condition. A negative correlation was found between levels of metal and hematocrit. No association was found between clinical signs and blood lead levels in Griffon vultures, except for digestive signs as stasis and weight loss. On numerous occasions, the intoxication in this specie is related to ingestion of lead ammunition; however, we have not detected radiographic lead in our vultures. Compared with other studies, we generally found low levels of lead in blood of Griffon vultures but the blood of all birds admitted to WRC presented detectable lead concentrations. This species apparently presents a higher sensibility to the toxic effects of this metal than that described by other authors. It have been observed that there is some evidence that suggests that subclinical levels of lead could be related with a predisposition to injury or diseases, even though these birds might be admitted for other causes. The

  8. Total contribution of airborne lead to blood lead.

    OpenAIRE

    Manton, W I

    1985-01-01

    A nine year study of blood lead concentrations and isotope ratios carried out on a married couple shows that pulmonary deposition cannot account for all the airborne lead in blood; that lead from bone may comprise 70% of blood lead; and that during pregnancy blood lead may double due to mobilisation of lead from bone.

  9. Iron, lead, and cobalt absorption: similarities and dissimilarities

    International Nuclear Information System (INIS)

    Barton, J.C.; Conrad, M.E.; Holland, R.

    1981-01-01

    Using isolated intestinal segments in rats, the absorption of iron, lead, and cobalt was increased in iron deficiency and decreased in iron loading. Similarly, the absorption of these metals was decreased in transfusional erythocytosis, after intravenous iron injection and after parenteral endotoxin injection. Acute bleeding or abbreviated intervals of dietary iron deprivation resulted in increased iron absorption from isolated intestinal segments and in intact animals, while the absorption of lead and cobalt was unaffected. These results suggest that the specificity of the mucosal metal absorptive mechanism is either selectively enhanced for iron absorption by phlebotomy or brief periods of dietary iron deprivation, or that two or more mucosal pathways for iron absorption may exist

  10. Analytical evidence of heterogeneous lead accumulation in the hypothalamic defence area and nucleus tractus solitarius.

    Science.gov (United States)

    Guimarães, D; Santos, J P; Carvalho, M L; Diniz, M S; House, B; Miller, V M

    2014-09-01

    Lead is a potent toxicant associated with adverse cardiovascular effects and hypertension in children. Yet, few studies have determined if autonomic dysfunction associated with lead exposure involves brain regions which regulate autonomic responses. Central autonomic nuclei such as the nucleus tractus solitarius (NTS) and hypothalamic defence area (HDA) may be particularly sensitive to lead infiltration because they are adjacent to ventricles and areas with semi-permeable blood-brain-barriers. To understand if autonomic nuclei are sensitive to lead accumulation Wistar rats were exposed to lead from the gestational period and lead levels were quantified in brain regions that regulate arterial pressure: the NTS and the HDA. Energy dispersive X-ray fluorescence (EDXRF) was used to quantify total brain lead levels and revealed no differences between exposed and control tissues; measured values were close to the detection limit (2μg/g). Electrothermal atomic absorption spectrometry (ETAAS) was also used, which has a greater sensitivity, to quantify lead. There was ∼2.1μg/g lead in the NTS and ∼3.1μg/g lead in the HDA of exposed rats, and no lead in the control rats. There were greater lead levels in the HDA (∼50%) as compared with the NTS. Pathology studies revealed more prominent lead granules in the HDA as compared with the NTS. Increased microglia and astrocyte activation was also noted in the NTS of lead exposed rats as compared with the HDA. Regional differences in neuro-inflammatory responses likely contribute to heterogeneous lead accumulation, with enhanced clearance of lead in the NTS. Future studies will resolve the mechanisms underpinning tissue-specific lead accumulation. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. The effect of lead intoxication on endocrine functions.

    Science.gov (United States)

    Doumouchtsis, K K; Doumouchtsis, S K; Doumouchtsis, E K; Perrea, D N

    2009-02-01

    Studies on the effects of lead on the endocrine system are mainly based on occupationally lead-exposed workers and experimental animal models. Although evidence is conflicting, it has been reported that accumulation of lead affects the majority of the endocrine glands. In particular, it appears to have an effect on the hypothalamic-pituitary axis causing blunted TSH, GH, and FSH/LH responses to TRH, GHRH, and GnRH stimulation, respectively. Suppressed GH release has been reported, probably caused by reduced synthesis of GHRH, inhibition of GHRH release or reduced somatotrope responsiveness. Higher levels of PRL in lead intoxication have been reported. In short-term lead-exposed individuals, high LH and FSH levels are usually associated to normal testosterone concentrations, whereas in long-term exposed individuals' low testosterone levels do not induce high LH and FSH concentrations. These findings suggest that lead initially causes some subclinical testicular damage, followed by hypothalamic or pituitary disturbance when longer periods of exposure take place. Similarly, lead accumulates in granulosa cells of the ovary, causing delays in growth and pubertal development and reduced fertility in females. In the parenchyma of adrenals histological and cytological changes are demonstrated, causing changes in plasma basal and stress-mediated corticosterone concentrations and reduced cytosolic and nuclear glucocorticoid receptor binding. Thyroid hormone kinetics are also affected. Central defect of the thyroid axis or an alteration in T4 metabolism or binding to proteins may be involved in derangements in thyroid hormone action. Lead toxicity involves alterations on calcitropic hormones' homeostasis, which increase the risk of skeletal disorders.

  12. Spiral waves in excitable media due to noise and periodic forcing

    Energy Technology Data Exchange (ETDEWEB)

    Yuan Guoyong, E-mail: g-y-yuan@sohu.com [Department of Physics, Hebei Normal University, Shijiazhuang 050016 (China); Hebei Advanced Thin Films Laboratory, Shijiazhuang 050016 (China); Xu Lin [Department of Physics, Hebei Normal University, Shijiazhuang 050016 (China); Xu Aiguo; Wang Guangrui [Institute of Applied Physics and Computational Mathematics, P.O. Box 8009, Beijing 100088 (China); Yang Shiping [Department of Physics, Hebei Normal University, Shijiazhuang 050016 (China); Hebei Advanced Thin Films Laboratory, Shijiazhuang 050016 (China)

    2011-09-15

    Highlights: > Excitable media jointly driven by periodic forcing and Gaussian white noise. > The joint driving leads to many unique tip motions. > New type of spiral wave breakup occurs between entrainment bands with 1:1 and 2:1. > Arnold tongues for different noise intensities exhibit stochastic resonance. > Fourier spectrum analysis can interpret tip motions and formation of entrainments. - Abstract: We investigate the jointly driven effects of external periodic forcing and Gaussian white noise on meandering spiral waves in excitable media with FitzHugh-Nagumo local dynamics. Interesting phenomena resulted from various forcing periods are found, for example, piece-wise line drift, intermittent straight-line drift and so on. We also observe new type of breakup of spiral wave between entrainment bands with 1:1 and 2:1. It is believed that the occurrence of the new type is relevant to the appearance of local bidirectional propagation window. There exist optimized noise intensities which can induce the broadest entrainments and Arnold tongues. Such a phenomenon is referred to as stochastic resonance. It is also observed that the noise makes significant effects on the spiral wave with straight-line drift. Via the tip Fourier spectrum, the varying of tip motion with external periods on the resonance band is interpreted.

  13. Total contribution of airborne lead to blood lead.

    Science.gov (United States)

    Manton, W I

    1985-01-01

    A nine year study of blood lead concentrations and isotope ratios carried out on a married couple shows that pulmonary deposition cannot account for all the airborne lead in blood; that lead from bone may comprise 70% of blood lead; and that during pregnancy blood lead may double due to mobilisation of lead from bone. PMID:3970881

  14. Contributing factors in self-poisoning leading to hospital admission in adolescents in northern Finland.

    Science.gov (United States)

    Liisanantti, Janne Henrik; Ala-Kokko, Tero Ilmari; Dunder, Teija Sinikka; Ebeling, Hanna Elina

    2010-07-01

    To evaluate the frequencies of different agents used in self-poisonings and acute factors contributing to intoxication of patients aged 12-18 years in northern Finland. Retrospective medical record review of all hospitalized patients during the period from January 1, 1991 to December 31, 2006. Cause of the admission, contributing factors, readmissions within one year. There were 309 admissions during the period, 54% were females. The leading cause of admission was alcohol, in 222 cases (71.8%). Hospitalizations related to alcohol consumption were associated with accidental poisoning in recreational use. There were no acute contributing factors in the majority of all patients. Over one-third of all intoxications were intentional self-harm, although previously diagnosed psychiatric diseases were rare. It is crucial to recognize adolescent psychiatric disorders in time and consult child and adolescent psychiatrist in case of poisoning.

  15. Vertebrate fauna of the Roman period, migrations period and Medieval period in Vojvodina (Serbia

    Directory of Open Access Journals (Sweden)

    Radmanović Darko P.

    2014-01-01

    Full Text Available Based on current published and unpublished research results, a total of 16 vertebrate species members of mammal (Mammalia, bird (Aves and osteichthyes (Osteichthyes classes have been registered at 11 archaeological sites from the Roman Period in Vojvodina. Mammals dominate with 12 species and one genus, birds are present with 3 species, and osteichthyes with one. From the Migration Period, at 9 sites, 22 vertebrate species have been registered, of which 13 species and one genus of mammals, 4 species and one genus of birds, and 5 species from the Osteichthyes class. At 8 sites from the Medieval Period, 16 vertebrate species have been registered. Mammals are the most numerous class with 10 species and one genus, while birds are present with 4 species and one genus. Furthermore, two species of osteichthyes have also been registered.

  16. Beeping and piping: characterization of two mechano-acoustic signals used by honey bees in swarming

    Science.gov (United States)

    Schlegel, Thomas; Visscher, P. Kirk; Seeley, Thomas D.

    2012-12-01

    Of the many signals used by honey bees during the process of swarming, two of them—the stop signal and the worker piping signal—are not easily distinguished for both are mechano-acoustic signals produced by scout bees who press their bodies against other bees while vibrating their wing muscles. To clarify the acoustic differences between these two signals, we recorded both signals from the same swarm and at the same time, and compared them in terms of signal duration, fundamental frequency, and frequency modulation. Stop signals and worker piping signals differ in all three variables: duration, 174 ± 64 vs. 602 ± 377 ms; fundamental frequency, 407 vs. 451 Hz; and frequency modulation, absent vs. present. While it remains unclear which differences the bees use to distinguish the two signals, it is clear that they do so for the signals have opposite effects. Stop signals cause inhibition of actively dancing scout bees whereas piping signals cause excitation of quietly resting non-scout bees.

  17. Setting and Reviewing Standards to Control Lead (Pb) Pollution

    Science.gov (United States)

    Lead (Pb) standards are part of the National Ambient Air Quality Standards (NAAQS), which limit air pollution to protect health and the environment. Standards are periodically reviewed and updated, and air quality across the U.S. is measured against them.

  18. Presence of lead in opium.

    Science.gov (United States)

    Aghaee-Afshar, Mahmoud; Khazaeli, Payam; Behnam, Behzad; Rezazadehkermani, Mohammad; Ashraf-Ganjooei, Narges

    2008-09-01

    Opium addiction is a common form of addiction in Middle East countries such as Iran. Recently several reports suggested some kinds of pathologic findings such as abdominal pain, nephropathy, and anemia in opium addict patients. Such pathologic findings suggest lead poisoning in the patients. In this study, the concentration of lead in 10 opium samples was evaluated. The mean concentration of lead in the opium samples was 1.88 ppm. This may explain some of the pathologic findings found in addict patients. The authors would suggest further investigations to evaluate the lead concentration in opium addicts' sera and also routine screening for lead poisoning in opium addict patients.

  19. Optical Frequency Mixing in Periodically-Patterned and in Quasi-Periodically-Patterned Nonlinear media

    International Nuclear Information System (INIS)

    Arie, A.

    1999-01-01

    Nonlinear frequency mixing processes, e.g. second harmonic generation, sum and difference frequency generation, etc., require matching of the phases of the interacting waves. The traditional method to achieve it is by selecting a specific angle of propagation in a birefringent nonlinear crystal. The main limitation of the birefringent phase matching method stems from the fact that for many interesting interactions, the phase matching condition cannot be satisfied in a specific crystal. This obstacle can be removed by the technique of quasi-phase-matching (QPM), where the nonlinear coefficient of the material is modulated at a fixed spatial frequency that equals the wave-vector phase mismatch between the interacting waves. An important development in recent years is the ability to periodically reverse the sign of the nonlinear coefficient in ferroelectric crystals by applying a high electric field through a periodic electrode. Some recent QPM interactions in periodically-poled KTP that were recently achieved at Tel-Aviv University include continuous-wave optical parametric oscillations, as well as generation of tunable mid-infrared radiation by difference frequency generation. Periodic patterning of the nonlinear coefficient enables to phase match only a single interaction. It would be advantageous to further extend the applications of this technique in order to simultaneously satisfy several interactions on a single crystal. This cannot be usually achieved in a periodic pattern, however more sophisticated quasi-periodic structures can be designed in this case. An interesting analogy can be drawn between artificially-made quasi-periodically-patterned nonlinear crystals and quasi-crystals found in nature, in rapidly-cooled metallic alloys

  20. X-ray investigations of lead shot pellets in the tissues of various species of birds found dead in Northern Germany

    International Nuclear Information System (INIS)

    Averbeck, C.; Kempen, E.; Petermann, S.; Prueter, J.; Vaur, G.; Visse, C.

    1990-01-01

    Within the period 1985-1988 467 specimens of dead or moribund birds including 51 species were collected in northern Germany, and x-rayed to ascertain lead pellet damage. In 15.8% of the cases evidence of lead bullets was found in the tissues. In over 80% of the cases lead pellets were found, and in 11 (14.9%) of the animals air rifle ammunition was discovered. Along with wood cock, greylag geese, and eider ducks several species of sea gulls were especially affected. The exact causes of death of the lead damaged birds could usually not be determined. The problems with lead pellet ammunition are presented and a legally designated maximum shooting distance is recommended. The replacement of lead pellets with small caliber ammunition for hunting from blinds is also discussed. Bullets are considered more effective for the hunting of knob-billed swans

  1. Effect of lead acetate on neurobehavioral development of rats

    Directory of Open Access Journals (Sweden)

    Mello C.F.

    1998-01-01

    Full Text Available We investigated the effects of lead exposure during the pre- and postnatal period on the neurobehavioral development of female Wistar rats (70-75 days of age, 120-150 g using a protocol of lead intoxication that does not affect weight gain. Wistar rats were submitted to lead acetate intoxication by giving their dams 1.0 mM lead acetate. Control dams received deionized water. Growth and neuromotor development were assessed by monitoring daily the following parameters in 20 litters: body weight, ear unfolding, incisor eruption, eye opening, righting, palmar grasp, negative geotaxis, cliff avoidance and startle reflex. Spontaneous alternation was assessed on postnatal day 17 using a T maze. The animals' ability to equilibrate on a beaker rim was measured on postnatal day 19. Lead intoxication was confirmed by measuring renal, hepatic and cerebral lead concentration in dams and litters. Lead treatment hastened the day of appearance of the following parameters: eye opening (control: 13.5 ± 0.6, N = 88; lead: 12.9 ± 0.6, N = 72; P<0.05, startle reflex (control: 13.0 ± 0.8, N = 88; lead: 12.0 ± 0.7, N = 72; P<0.05 and negative geotaxis. On the other hand, spontaneous alternation performance was hindered in lead-exposed animals (control: 37.6 ± 19.7; lead: 57.5 ± 28.3% of alternating animals; P<0.05. These results suggest that lead exposure without concomitant undernutrition alters rat development, affecting specific subsets of motor skills.

  2. Thyrotoxic periodic paralysis due to excessive L-thyroxine replacement in a Caucasian man.

    LENUS (Irish Health Repository)

    Hannon, M J

    2009-09-01

    Thyrotoxic periodic paralysis is a potentially fatal complication of hyperthyroidism, more common in Asian races, which is defined by a massive intracellular flux of potassium. This leads to profound hypokalaemia and muscle paralysis. Although the paralysis is temporary, it may be lethal if not diagnosed and treated rapidly, as profound hypokalaemia may induce respiratory muscle paralysis or cardiac arrest. The condition is often misdiagnosed in the west due to its comparative rarity in Caucasians; however it is now increasingly described in Caucasians and is also being seen with increasing frequency in western hospitals due to increasing immigration and population mobility. Here we describe the case of a patient with panhypopituitarism due to a craniopharyngioma, who developed thyrotoxic periodic paralysis due to excessive L-thyroxine replacement. This disorder has been described in Asian subjects but, to our knowledge, thyrotoxic periodic paralysis secondary to excessive L-thyroxine replacement has never been described in Caucasians.

  3. Lead transfer in maternal milk, and the absorption, retention, distribution and excretion of lead in suckling mice

    Energy Technology Data Exchange (ETDEWEB)

    Keller, Charles Arthur [Univ. of Rochester, NY (United States). Dept. of Radiation Biology and Biophysics

    1980-01-01

    Suckling mice were found to absorb and retain a greater fraction of an oral lead dose than did adult mice. Pinocytotic activity and lead uptake (in vivo) were found to be greatest in the distal small intestinal tissue. Cortisone pretreatment results in precocious cessation of pinocytotic activity in the intestine of suckling mice. Cortisone pretreatment of adult mice had no effect on whole body lead retention or intestinal tissue content of lead following an oral dose. The data indicate that the distal small intestine is the site of active pinocytosis of lead, and that pinocytosis is the major mechanism involved in lead absorption in suckling mice. Developmental differences were also observed in the percentage of lead retained in the whole body. Both groups exhibited dose-independent lead retention, indicating a first-order absorption process for each age group. Lead distribution and elimination from organs also differed between suckling and adult mice. Developmental differences were observed in organ lead concentration for kidneys and brain following oral doses. Relative distribution of lead to the brains of suckling mice were greater than to adult brains. Whole body and bone lead elimination rates were reduced in suckling compared to adult mice. Brain lead elimination rates did not differ in suckling and adult mice. A lactating mouse model was developed to study lead transfer to suckling offspring. Lead was transferred in milk to suckling offspring from mothers which had previously ingested lead in the drinking water. Relative lead transfer to suckled offspring during lactation greatly exceeded transfer to fetuses during gestation. Lactation resulted in an increased rate of maternal lead elimination. Lead concentration in milk exceeded plasma concentration by a factor of approximately 25. (ERB)

  4. Lead remediation and changes in human lead exposure: some physiological and biokinetic dimensions.

    Science.gov (United States)

    Mushak, Paul

    2003-02-15

    This paper presents a qualitative and quantitative analysis of the various aspects of lead remediation effectiveness with particular reference to human health risk assessment. One of the key elements of lead remediation efforts at such sites as those under the Superfund program deals with populations at elevated exposure and toxicity risk in the proximity of, or at, the site of remediation, especially remediation workers, workers at other tasks on sites that were remediated down to some action level of lead concentration in soils, and groups at risk in nearby communities. A second element has to do with how one measures or models lead exposure changes with special reference to baseline and post-remediation conditions. Various biomarkers of lead exposure can be employed, but their use requires detailed knowledge of what results using each means. The most commonly used approach is measurement of blood lead (Pb-B). Recognized limitations in the use of Pb-B has led to the use of predictive Pb exposure models, which are less vulnerable to the many behavioral, physiological, and environmental parameters that can distort isolated or 'single shot' Pb-B testings. A third aspect covered in this paper presents various physiological factors that affect the methods by which one evaluates Pb remediation effectiveness. Finally, this article offers an integrated look at how lead remediation actions directed at one lead source or pathway affect the total lead exposure picture for human populations at elevated lead exposure and toxicity risk.

  5. Periodic waves in nonlinear metamaterials

    International Nuclear Information System (INIS)

    Liu, Wen-Jun; Xiao, Jing-Hua; Yan, Jie-Yun; Tian, Bo

    2012-01-01

    Periodic waves are presented in this Letter. With symbolic computation, equations for monochromatic waves are studied, and analytic periodic waves are obtained. Factors affecting properties of periodic waves are analyzed. Nonlinear metamaterials, with the continuous distribution of the dielectric permittivity obtained, are different from the ones with the discrete distribution. -- Highlights: ► Equations for the monochromatic waves in transverse magnetic polarization have been studied. ► Analytic periodic waves for the equations have been obtained. ► Periodic waves are theoretically presented and studied in the nonlinear metamaterials.

  6. Lead intoxication in dogs: risk assessment of feeding dogs trimmings of lead-shot game.

    Science.gov (United States)

    Høgåsen, Helga R; Ørnsrud, Robin; Knutsen, Helle K; Bernhoft, Aksel

    2016-07-25

    Expanding lead-based bullets, commonly used for hunting of big game, produce a scattering of lead particles in the carcass around the wound channel. Trimmings around this channel, which are sometimes fed to dogs, may contain lead particles. The aim of this study was to assess potential health effects of feeding dogs such trimmings. Lead ingestion most commonly causes gastrointestinal and neurological clinical signs, although renal, skeletal, haematological, cardiovascular and biochemical effects have also been reported. Experimental data indicate that a daily dose of around 1 mg lead as lead acetate/kg body weight for ten days may be considered as a Lowest Observed Effect Level in dogs. Acute toxicity documentation from the Centers for Disease Control and Prevention indicates 300 mg/kg body weight as the lowest dose of lead acetate causing death in dogs after oral ingestion. Our assessment suggests that dogs fed trimmings of lead-shot game may be affected by the amounts of lead present, and that even deadly exposure could occasionally occur. The intestinal absorption of lead from bullets was assumed to be 10-80 % of that of lead acetate, reflecting both the variability in particle size and uncertainty about the bioavailability of metallic lead in dogs. Despite data gaps, this study indicates that feeding dogs trimmings of lead-shot game may represent a risk of lead intoxication. More research is needed to assess the exact consequences, if lead-based bullets are still to be used. Meanwhile, we recommend that trimmings close to the wound channel should be made inaccessible to dogs, as well as to other domestic or wild animals.

  7. Effect of short-term administration of lead to pregnant rats

    Energy Technology Data Exchange (ETDEWEB)

    Hubermont, G; Buchet, J P; Roels, H; Lauwerys, R

    1976-03-01

    Lead was administered to adult female rats in drinking water (0; 0.1; 1 and 10 ppM) for 3 weeks before mating, during pregnancy and during 3 weeks after delivery. On day 21 after delivery the mothers and their newborns were sacrificed and various parameters of blood--lead concentration (Pb-B), hematocrit (Htc), hemoglobin (Hb), free erythrocyte porphyrins (FEP), delta-aminolevulinate dehydratase (ALAD)--and tissue--ALAD, free tissue porphyrins (FTP), lead concentration (Pb-T)--were determined. In mothers a significant increase in Pb-B and Pb concentration in kidney was found in the 10 ppM group, but this increase in lead concentration was not associated with any statistically significant modification of the biochemical parameters. In newborns, lead concentration in blood and in kidney was also significantly increased in the 10 ppm group and this lead exposure was associated with a decrease of the ALAD activity in blood and an increase of FTP in kidney. On the basis of the biochemical parameters investigated it was concluded that the developing organism is more susceptible to the biological action of lead than the organism of adult animals and that the ''no-effect'' level of lead administered during pregnancy and in the neonatal period is around 1 ppM.

  8. 404 water quality and syndicated lead burden of a community

    African Journals Online (AJOL)

    Osondu

    1993-12-30

    Dec 30, 1993 ... level water samples over the study period were, pH 6.7, TDS 66.0, TOC 2.3, NO3 ... High lead concentration as recorded in this study is a source of worry in view of the health .... analyses including pH, residual chlorine,.

  9. On complex periodic motions and bifurcations in a periodically forced, damped, hardening Duffing oscillator

    International Nuclear Information System (INIS)

    Guo, Yu; Luo, Albert C.J.

    2015-01-01

    In this paper, analytically predicted are complex periodic motions in the periodically forced, damped, hardening Duffing oscillator through discrete implicit maps of the corresponding differential equations. Bifurcation trees of periodic motions to chaos in such a hardening Duffing oscillator are obtained. The stability and bifurcation analysis of periodic motion in the bifurcation trees is carried out by eigenvalue analysis. The solutions of all discrete nodes of periodic motions are computed by the mapping structures of discrete implicit mapping. The frequency-amplitude characteristics of periodic motions are computed that are based on the discrete Fourier series. Thus, the bifurcation trees of periodic motions are also presented through frequency-amplitude curves. Finally, based on the analytical predictions, the initial conditions of periodic motions are selected, and numerical simulations of periodic motions are carried out for comparison of numerical and analytical predictions. The harmonic amplitude spectrums are also given for the approximate analytical expressions of periodic motions, which can also be used for comparison with experimental measurement. This study will give a better understanding of complex periodic motions in the hardening Duffing oscillator.

  10. The optimum lead thickness for lead-activation detectors

    International Nuclear Information System (INIS)

    Si Fenni; Hu Qingyuan

    2009-01-01

    The optimum lead thickness for lead-activation detectors has been studied in this paper. First existence of the optimum lead thickness is explained theoretically. Then the optimum lead thickness is obtained by two methods, MCNP5 calculation and mathematical estimation. At last factors which affect the optimum lead thickness are discussed. It turns out that the optimum lead thickness is irrelevant to incident neutron energies. It is recommended 2.5 cm generally.

  11. Some Interesting Events from Lead-Lead Collisions in ATLAS at the LHC (individual captions in abstract)

    CERN Multimedia

    The ATLAS Experiment, ATLAS, First collisions, Splash events

    2010-01-01

    Image Captions CERN-EX-1011310 01 -- Event display of a highly asymmetric dijet event, with one jet with ET > 100 GeV and no evident recoiling jet, recorded by ATLAS in LHC lead-lead collisions. CERN-EX-1011310 02 -- Event display of a highly asymmetric dijet event, with one jet with ET > 100 GeV and no evident recoiling jet, recorded by ATLAS in LHC lead-lead collisions. CERN-EX-1011310 03 -- Event display of a highly asymmetric dijet event, with one jet with ET > 100 GeV and no evident recoiling jet, recorded by ATLAS in LHC lead-lead collisions. CERN-EX-1011310 04 -- LHC lead-lead collisions recorded by ATLAS with a candidate Z to μ+μ- decay. The two muons shown in purple are the candidates to originate from the Z decay. The transverse momenta of these two muons are 44 and 45 GeV, and the invariant mass of the dimuon system is 93 GeV. CERN-EX-1011310 05 -- LHC lead-lead collisions recorded by ATLAS with a candidate Z to μ+μ- decay. The two muons shown in red are the candidates to originate from the...

  12. Trends in motor neuron disease: association with latitude and air lead levels in Spain.

    Science.gov (United States)

    Santurtún, Ana; Villar, Alejandro; Delgado-Alvarado, Manuel; Riancho, Javier

    2016-08-01

    Motor neuron diseases (MND) are a group of disorders characterized by motor neuron degeneration. Among them, amyotrophic lateral sclerosis (ALS) is by far the most common in adulthood. This paper assesses the trend and geographical pattern in MND incidence in Spain and the possible air lead levels effect on this pathology. To confirm this concept, we performed a retrospective analysis of the deaths due to MND in Spain during 2000 and 2013, determined the geographical differences, and explored the relationship between MND and the air levels of lead. Overall, between 2000 and 2013, 11,355 people died in Spain because of MND. Disease mortality significantly increased in recent years (2007-2013) when compared with the first time of the period. Spearman's rank correlation coefficient also showed a statistically significant positive trend (CC = 0.824, p = 0.0002). Among people over 65 years, mortality rates were higher in Northern provinces. Moreover, we found a significant association of MND mortality with higher air lead levels (CC = 0.457, p = 0.01). Our study confirms that MND mortality is increasing in Spain, with a significant latitude gradient, which suggests an important role of environmental exposures. This ecological study suggests that air lead levels may be implicated in ALS pathogenesis.

  13. Deposition of heavy metal in the environment. Balances of the consumption and fate of lead and cadmium 1984-1989

    International Nuclear Information System (INIS)

    Balzer, D.

    1991-10-01

    The data on the consumption and fate of lead and cadmium as well as their compounds was compiled in a balance for the Federal Republic of Germany for the period between 1984 and 1989. To obtain a general overview of the known mass flows, additional flow sheets for lead and cadmium were drawn up. (orig./BBR) [de

  14. Mortality from heart attack in Belgrade population during the period 1990-2004

    Directory of Open Access Journals (Sweden)

    Ratkov Isidora

    2008-01-01

    Full Text Available INTRODUCTION In most countries, cardiovascular diseases are the leading disorders, with ischemic heart diseases being the leading cause of death. According to WHO data, every year about 17 million people die of cardiovascular diseases, which is 30% of all deaths. Ischemic heart diseases contribute from one-third to one-half of all deaths due to cardiovascular diseases. Three point eight million men and 3.4 million women in the world die every year from ischemic heart diseases, and in Europe about 2 million. The highest mortality rate from ischemic heart diseases occurs in India, China and Russia. OBJECTIVE The aim of this descriptive epidemiological study was to determine heart attack mortality in Belgrade population during the period 1990-2004. METHOD In the study, we conducted investigation of Belgrade population during the period 1990-2004. Mortality data were obtained from the city institution for statistics. The mortality rates were calculated based on the total Belgrade population obtained from the mean values for the last two register years (1991 and 2002. The mortality rates were standardized using the direct method of standardization according to the world (Segi standard population. RESULTS In the Belgrade population during the period 1990-2004, the participation of mortality rate due to heart attack among deaths from cardiovascular diseases was 17% in males and 10% in females. In Belgrade male population, mean standardized mortality rates (per 100,000 habitants were 50.5 for heart attack, 8.3 for chronic ischemic heart diseases and 4.6 for angina pectoris, while in females the rates were 30.8, 6.7 and 4.2, respectively. Mortality from ischemic heart diseases and from heart attack was higher in males than in females. During the studied 15-year period, on average 755 males and 483 females died due to heart attack every year. Mean standardized mortality rates per 100,000 habitants were 50.0 in male and 31.1 in female population. Males

  15. Minimum period and the gap in periods of Cataclysmic binaries

    International Nuclear Information System (INIS)

    Paczynski, B.; Sienkiewicz, R.

    1983-01-01

    The 81 minute cutoff to the orbital periods of hydrogen-rich cataclysmic binaries is consistent with evolution of those systems being dominated by angular momentum losses due to gravitational radiation. Unfortunately, many uncertainties, mainly poorly known atmospheric opacities below 2000 K, make is physically impossible to verify the quadrupole formula for gravitational radiation by using the observed cutoff at 81 minutes. The upper boundary of the gap in orbital periods observed at about 3 hours is almost certainly due to enhanced angular momentum losses from cataclysmic binaries which have longer periods. The physical mechanism of those losses is not identified, but a possible importance of stellar winds is pointed out. The lower boundary of the gap may be explained with the oldest cataclysmic binaries, whose periods evolved past the minimum at 81 minutes and reached the value of 2 hours within about 12 x 10 9 years after the binary had formed. Those binaries should have secondary components of only 0.02 solar masses, and their periods could be used to estimate ages of the oldest cataclysmic stars, and presumably the age of Galaxy. An alternative explanation for the gap requires that binaries should be detached while crossing the gap. A possible mechanism for this phenomenon is discussed. It requires the secondary components to be about 0.2 solar masses in the binaries just below the gap

  16. 32 CFR 213.1 - Purpose.

    Science.gov (United States)

    2010-07-01

    ... obtained at http://www.dtic.mil/whs/directives/. (c) Designates the Secretary of the Army as the DoD....mil/whs/directives/. (1) For DoD support to the Boy Scouts of America (BSA) and Girl Scouts of the...

  17. Heavy flavour production in proton-lead and lead-lead collisions with LHCb

    Science.gov (United States)

    Winn, Michael

    2017-11-01

    The LHCb experiment offers the unique opportunity to study heavy-ion interactions in the forward region (2 kinematic domain complementary to the other 3 large experiments at the LHC. The detector has excellent capabilities for reconstructing quarkonia and open charm states, including baryons, down to zero pT. It can separate the prompt and displaced charm components. In pPb collisions, both forward and backward rapidities are covered thanks to the possibility of beam reversal. Results include measurements of the nuclear modification factor and forward-backward ratio for charmonium, open charm and bottomonium states. These quantities are sensitive probes for nuclear effects in heavy flavour production. Perspectives are given with the large accumulated luminosity during the 2016 pPb run at the LHC. In 2015, LHCb participated successfully for the first time in the PbPb data-taking. The status of the forward prompt J/ψ nuclear modification factor measurement in lead-lead collisions is discussed.

  18. Lead poisoning

    Energy Technology Data Exchange (ETDEWEB)

    Beijers, J A

    1952-01-01

    Three cases of acute lead poisoning of cattle herds via ingestion are reported, and reference is made to several other incidents of lead in both humans and animals. The quantity of lead which was found in the livers of the dead cows varied from 6.5 to 19 mg/kg, while 1160 mg/kg of lead in the liver was found for a young cow which was poisoned experimentally with 5 gms of lead acetate per day; hence, there appears to be great variability in the amounts deposited that can lead to intoxication and death. No evidence was found for a lead seam around the teeth, prophyrinuria, or basophil granules in the erythrocytes during acute or chronic lead poisoning of cattle or horses examined. Reference is made to attempts of finding the boundary line between increased lead absorption and lead intoxication in humans, and an examination of 60 laborers in an offset-printing office containing a great deal of inhalable lead (0.16 to 1.9 mg/cu m air) is reviewed. Physical deviation, basophylic granulation of erythrocytes, increased lead content of the urine, and porphyrinuria only indicate an increased absorption of lead; the use of the term intoxication is justified if, in addition, there are complaints of lack of appetite, constipation, fatigue, abdominal pain, and emaciation.

  19. The calculation of collective energies from periodic time-dependent Hartree-Fock solutions

    International Nuclear Information System (INIS)

    Zahed, I.; Baranger, M.

    1983-06-01

    A periodic TDHF solution is used as the reference state for a diagrammatic expansion of the propagator. A discrete Fourier transform leads to a function of energy, whose poles are the corresponding energy levels. Limiting the expansion to first-order diagrams leads to a new derivation of the Bohr-Sommerfeld-like quantization rule for collective states

  20. Observation of quasi-periodic solar radio bursts associated with propagating fast-mode waves

    Science.gov (United States)

    Goddard, C. R.; Nisticò, G.; Nakariakov, V. M.; Zimovets, I. V.; White, S. M.

    2016-10-01

    Aims: Radio emission observations from the Learmonth and Bruny Island radio spectrographs are analysed to determine the nature of a train of discrete, periodic radio "sparks" (finite-bandwidth, short-duration isolated radio features) which precede a type II burst. We analyse extreme ultraviolet (EUV) imaging from SDO/AIA at multiple wavelengths and identify a series of quasi-periodic rapidly-propagating enhancements, which we interpret as a fast wave train, and link these to the detected radio features. Methods: The speeds and positions of the periodic rapidly propagating fast waves and the coronal mass ejection (CME) were recorded using running-difference images and time-distance analysis. From the frequency of the radio sparks the local electron density at the emission location was estimated for each. Using an empirical model for the scaling of density in the corona, the calculated electron density was used to obtain the height above the surface at which the emission occurs, and the propagation velocity of the emission location. Results: The period of the radio sparks, δtr = 1.78 ± 0.04 min, matches the period of the fast wave train observed at 171 Å, δtEUV = 1.7 ± 0.2 min. The inferred speed of the emission location of the radio sparks, 630 km s-1, is comparable to the measured speed of the CME leading edge, 500 km s-1, and the speeds derived from the drifting of the type II lanes. The calculated height of the radio emission (obtained from the density) matches the observed location of the CME leading edge. From the above evidence we propose that the radio sparks are caused by the quasi-periodic fast waves, and the emission is generated as they catch up and interact with the leading edge of the CME. The movie associated to Fig. 2 is available at http://www.aanda.org

  1. Determining tissue-lead levels in large game mammals harvested with lead bullets: human health concerns.

    Science.gov (United States)

    Tsuji, L J S; Wainman, B C; Jayasinghe, R K; VanSpronsen, E P; Liberda, E N

    2009-04-01

    Recently, the use of lead isotope ratios has definitively identified lead ammunition as a source of lead exposure for First Nations people, but the isotope ratios for lead pellets and bullets were indistinguishable. Thus, lead-contaminated meat from game harvested with lead bullets may also be contributing to the lead body burden; however, few studies have determined if lead bullet fragments are present in big game carcasses. We found elevated tissue-lead concentrations (up to 5,726.0 microg/g ww) in liver (5/9) and muscle (6/7) samples of big game harvested with lead bullets and radiographic evidence of lead fragments. Thus, we would advise that the tissue surrounding the wound channel be removed and discarded, as this tissue may be contaminated by lead bullet fragments.

  2. Lead isotopes reveal different sources of lead in balsamic and other vinegars

    International Nuclear Information System (INIS)

    Ndung'u, Kuria; Hibdon, Sharon; Veron, Alain; Flegal, A. Russell

    2011-01-01

    Fifty-eight brands of balsamic vinegars were analyzed for lead concentrations and isotopic compositions ( 204 Pb, 206 Pb, 207 Pb, and 208 Pb) to test the findings of a previous study indicating relatively high levels of lead contamination in some of those vinegars - more than two thirds (70%) of them exceeded California's State Maximum Level (34 μg/L) based on consumption rates ≥ 0.5 μg Pb per day. The Lead isotopic fingerprints of all those vinegars with high lead concentrations were then found to be primarily anthropogenic. This isotopic analysis unquestionably reveals multiple contamination sources including atmospheric pollutant Pb and an unidentified contamination source, likely occurring after grape harvest. Organically grown grape vinegars display the same Pb content and isotopic signatures as other vinegars. This implies that pesticides might not be a significant source of pollutant Pb in vinegars. A significant post-harvest contamination would be inherited from chemicals added during production and/or material used during transport, processing or storage of these vinegars. This is consistent with the highest Pb levels being found in aged vinegars (112 ± 112 μg/L) in contrast to other vinegars (41.6 ± 28.9 μg/L) suggesting contamination during storage. It is, therefore, projected that lead levels in most vinegars, especially aged balsamic and wine vinegars, will decrease with improvements in their manufacture and storage processes consequential to recent concerns of elevated levels of lead in some vinegars. - Highlights: → First extensive study on content and possible sources of lead in balsamic vinegars. → Half of the vinegars exceed California's State Maximum Level for human consumption. → Lead content in vinegars seems to be mainly post-harvest from industrial processes.

  3. Periods of weed interference in maize crops cultivated in the first and second cycles

    Directory of Open Access Journals (Sweden)

    Caio Ferraz de Campos

    2016-10-01

    Full Text Available The interference of weeds in maize production may be reflected in grain yield losses that vary as a function of the density, stage and degree of aggressiveness of the species present. In the agricultural ecosystem, crops and weeds demand light, water, nutrients and space, which are frequently not available in sufficient quantities, leading to competition. The aim of this work was to determine the period of interference of weed plants, in particular of naked crabgrass (Digitaria nuda on maize crop in the first and second harvest. The treatments were defined as increasing periods of coexistence and increasing control of weed community (7, 14, 21, 28, 35, 42, 49, and 56 days, two more controls, a control including one with weed control until the end of the culture cycle and another with coexistence until the harvest. For each period, were evaluated the stand of maize plants, length of ear, number of grains per row, number of rows per ear, cob, 100-grain weight, and grain productivity. The data obtained were subjected to analysis of variance using the F test, with average treatments compared using Tukey’s test at 5% probability. Crop productivity was evaluated by means of regressions, the critical periods of interference were estimated. The critical timing of weed removal was 25 days for both harvests. The critical weed free period was 54 and 27 days for the first and second harvest respectively. For the conditions of the first and second harvest, the critical period of weed control was of 29 and 2 days respectively.

  4. Arkansas People Participating in Lead Education (APPLE): results of a lead-safe training program.

    Science.gov (United States)

    Ferguson, Alesia; Bursac, Zoran; Kern, David F

    2011-06-01

    Lead is still seen as one of the most harmful environmental toxins for young children, with the predominant source being deteriorating lead-based paint. Those at continued risk include those living in homes built before 1978, renovators and remodelers, and especially those with limited access to proper healthcare and diets. Proper training on lead-safe work practices focused on preventing and reducing the spread of lead dust can help reduce lead exposure. Presented in this paper are experiences in delivering lead-safe work practices training in six Arkansas cities, and results from pre- and post- surveys delivered before and immediately after the training. Pre- and post-surveys assess strong and weak areas of training. Participants demonstrated positive shifts in attitude and behavior towards lead-safe work practices following training. However, our research found that more emphasis should be focused on clarifying current lead exposure sources and routes for children.

  5. Thermal decomposition of γ-irradiated lead nitrate

    International Nuclear Information System (INIS)

    Nair, S.M.K.; Kumar, T.S.S.

    1990-01-01

    The thermal decomposition of unirradiated and γ-irradiated lead nitrate was studied by the gas evolution method. The decomposition proceeds through initial gas evolution, a short induction period, an acceleratory stage and a decay stage. The acceleratory and decay stages follow the Avrami-Erofeev equation. Irradiation enhances the decomposition but does not affect the shape of the decomposition curve. (author) 10 refs.; 7 figs.; 2 tabs

  6. Blood Lead Level in Children with Neurological Disorders.

    Science.gov (United States)

    Parhoudeh, Marzieh; Inaloo, Soroor; Zahmatkeshan, Mozhgan; Seratishirazi, Zahra; Haghbin, Saeedeh

    2018-01-01

    We aimed to investigate the blood lead level (BLL) in children with neurologic disorders of unknown causes and compare with normal children. In this prospective case-control study, 68 patients aged 1 to 18 yr with neurologic disorders of unknown causes, were referred to pediatric neurology clinics and wards, Shiraz, Iran selected during a 12 months period from Sep 2013. They were compared with 1:1 ratio, age, and sex-matched healthy children. BLL was checked from all participants using 3 cc heparinized venous blood sample. Level of ≥5 mcg/dl was considered toxic dose. Totally, 136 children (68 cases and 68 controls) with mean ages of 5.20±4.12 and 4.18±3.86 yr, respectively, were enrolled. Mean BLL was higher in case group than in controls but the difference was not significant ( P =0.84), though they were less than toxic levels in both. In addition, the difference in mean BLLs was not significant in terms of living place, sex, and age. Totally, 17.7% of the study sample had BLL ≥5 mcg/dl. The frequency of BLL ≥5 mcg/dl was significantly higher in case group ( P =0.024) with an odds ratio 2.9 times higher (95% CI: 1.066-7.60). Strategies in public health must focus on practicing primary and secondary preventions of lead exposure in children.

  7. Biological fractionation of lead isotopes in Sprague-Dawley rats lead poisoned via the respiratory tract.

    Directory of Open Access Journals (Sweden)

    Jing Wu

    Full Text Available It was considered that lead isotope ratios did not change during physical, chemical, or biological processes. Thus, lead isotope ratios have been used as fingerprints to identify possible lead sources. However, recent evidence has shown that the lead isotope ratios among different biological samples in human are not always identical from its lead origins in vitro. An animal experiment was conducted to explore the biological fractionation of lead isotopes in biological systems.24 male Sprague-Dawley (SD rats were divided into groups that received acute lead exposure (0, 0.02, 0.2, or 2 mg/kg body weight of lead acetate via the respiratory route every day for 5 days. Biological samples (i.e., blood, urine, and feces were collected for comparison with the lead acetate (test substance and the low-lead animal feed (diet administered to the rats. The lead isotope ratios were determined by inductively coupled plasma mass spectrometry (ICP-MS.There are significant differences (p<0.05 in lead isotope ratios between blood, urine, and feces. Moreover, a nonlinear relationship between the blood lead concentration and the blood lead isotope ratios was observed. There is also a threshold effect to the fractionation function. Only the blood isotope ratio of (204Pb/(206Pb matches the test substance well. As for feces, when (204Pb/(206Pb ratio is considered, there is no significant difference between feces-test substance pairs in medium and high dose group.The biological fractionation of lead isotopes in SD rats was observed. Moreover, there might be a threshold for the biological fractionation of lead isotopes which is depending on whole blood lead level. It is considered to be more reliable that we compared the isotope ratios of potential lead hazards with both blood and feces lead fingerprints especially for (204Pb/(206Pb ratio under high-dose exposure.

  8. The lead-poisoned genius: saturnism in famous artists across five centuries.

    Science.gov (United States)

    Montes-Santiago, Julio

    2013-01-01

    Lead poisoning (saturnism) has been present throughout the history of mankind. In addition to possible ingestion from contaminated food, one of the most important ways in which poisoning caused morbid processes was by occupational exposure. This exposition was pandemic in the Roman Empire, and it has been claimed that it contributed to its fall, but it also caused numerous epidemics in Western countries until the nineteenth century. In the case of artists, and since the Renaissance period, this toxicity has been called painter's colic or painter's madness. The latter term is partly due to the mental disorders displayed by some of the great masters, including Michelangelo and Caravaggio, although it was long recognized that even house and industrial painters were prone to the disorder. This chapter examines the historical evidence of recognition of such toxicity and discusses the controversies raised by the possibility of professional lead poisoning in great artists. In addition to those mentioned above, many other artists across several centuries will be discussed, some being Rubens, Goya, Fortuny, Van Gogh, Renoir, Dufy, Klee, Frida Kahlo, and Portinari. This chapter also briefly mentions the possibility of lead poisoning in two famous composers: Beethoven and Handel. Whether suffering from lead poisoning or not, about which we cannot always be sure, we should still highlight and admire such geniuses fighting their disorders to bequeath us their immortals works. © 2013 Elsevier B.V. All rights reserved.

  9. Numerical Simulation of Cylindrical Solitary Waves in Periodic Media

    KAUST Repository

    Quezada de Luna, Manuel; Ketcheson, David I.

    2013-01-01

    We study the behavior of nonlinear waves in a two-dimensional medium with density and stress relation that vary periodically in space. Efficient approximate Riemann solvers are developed for the corresponding variable-coefficient first-order hyperbolic system. We present direct numerical simulations of this multiscale problem, focused on the propagation of a single localized perturbation in media with strongly varying impedance. For the conditions studied, we find little evidence of shock formation. Instead, solutions consist primarily of solitary waves. These solitary waves are observed to be stable over long times and to interact in a manner approximately like solitons. The system considered has no dispersive terms; these solitary waves arise due to the material heterogeneity, which leads to strong reflections and effective dispersion.

  10. Numerical Simulation of Cylindrical Solitary Waves in Periodic Media

    KAUST Repository

    Quezada de Luna, Manuel

    2013-07-14

    We study the behavior of nonlinear waves in a two-dimensional medium with density and stress relation that vary periodically in space. Efficient approximate Riemann solvers are developed for the corresponding variable-coefficient first-order hyperbolic system. We present direct numerical simulations of this multiscale problem, focused on the propagation of a single localized perturbation in media with strongly varying impedance. For the conditions studied, we find little evidence of shock formation. Instead, solutions consist primarily of solitary waves. These solitary waves are observed to be stable over long times and to interact in a manner approximately like solitons. The system considered has no dispersive terms; these solitary waves arise due to the material heterogeneity, which leads to strong reflections and effective dispersion.

  11. Quasi-periodic fractal patterns in geomagnetic reversals, geological activity, and astronomical events

    International Nuclear Information System (INIS)

    Puetz, Stephen J.; Borchardt, Glenn

    2015-01-01

    Highlights: • Spectral analysis indicates similar harmonics in astronomical and geological events. • Quasi-periodic cycles occur in tripling patterns of 30.44, 91.33, 274, 822, and 2466 myr. • Similar astro- and geo-phases suggest that the cycles develop from a common source. - Abstract: The cause of geomagnetic reversals remains a geological mystery. With the availability of improved paleomagnetic databases in the past three years, a reexamination of possible periodicity in the geomagnetic reversal rate seems warranted. Previous reports of cyclicity in the reversal rate, along with the recent discovery of harmonic cycles in a variety of natural events, sparked our interest in reevaluating possible patterns in the reversal rate. Here, we focus on geomagnetic periodicity, but also analyze paleointensity, zircon formation, star formation, quasar formation, supernova, and gamma ray burst records to determine if patterns that occur in other types of data have similar periodicity. If so, then the degree of synchronization will indicate likely causal relationships with geomagnetic reversals. To achieve that goal, newly available time-series records from these disciplines were tested for cyclicity by using spectral analysis and time-lagged cross-correlation techniques. The results showed evidence of period-tripled cycles of 30.44, 91.33, 274, 822, and 2466 million years, corresponding to the periodicity from a new Universal Cycle model. Based on the results, a fractal model of the universe is hypothesized in which sub-electron fractal matter acts as a dynamic medium for large-scale waves that cause the cycles in astronomical and geological processes. According to this hypothesis, the medium of sub-electron fractal matter periodically compresses and decompresses according to the standard laws for mechanical waves. Consequently, the compressions contribute to high-pressure environments and vice versa for the decompressions, which are hypothesized to cause the

  12. The Discrete Beverton-Holt Model with Periodic Harvesting in a Periodically Fluctuating Environment

    Directory of Open Access Journals (Sweden)

    Ziyad AlSharawi

    2010-01-01

    Full Text Available We investigate the effect of constant and periodic harvesting on the Beverton-Holt model in a periodically fluctuating environment. We show that in a periodically fluctuating environment, periodic harvesting gives a better maximum sustainable yield compared to constant harvesting. However, if one can also fix the environment, then constant harvesting in a constant environment can be a better option, especially for sufficiently large initial populations. Also, we investigate the combinatorial structure of the periodic sequence of carrying capacities and its effect on the maximum sustainable yield. Finally, we leave some questions worth further investigations.

  13. Biosorption of lead phosphates by lead-tolerant bacteria as a mechanism for lead immobilization.

    Science.gov (United States)

    Rodríguez-Sánchez, Viridiana; Guzmán-Moreno, Jesús; Rodríguez-González, Vicente; Flores-de la Torre, Juan Armando; Ramírez-Santoyo, Rosa María; Vidales-Rodríguez, Luz Elena

    2017-08-01

    The study of metal-tolerant bacteria is important for bioremediation of contaminated environments and development of green technologies for material synthesis due to their potential to transform toxic metal ions into less toxic compounds by mechanisms such as reduction, oxidation and/or sequestration. In this study, we report the isolation of seven lead-tolerant bacteria from a metal-contaminated site at Zacatecas, México. The bacteria were identified as members of the Staphylococcus and Bacillus genera by microscopic, biochemical and 16S rDNA analyses. Minimal inhibitory concentration of these isolates was established between 4.5 and 7.0 mM of Pb(NO 3 ) 2 in solid and 1.0-4.0 mM of Pb(NO 3 ) 2 in liquid media. A quantitative analysis of the lead associated to bacterial biomass in growing cultures, revealed that the percentage of lead associated to biomass was between 1 and 37% in the PbT isolates. A mechanism of complexation/biosorption of lead ions as inorganic phosphates (lead hydroxyapatite and pyromorphite) in bacterial biomass, was determined by Fourier transform infrared spectroscopy and X-ray diffraction analyses. Thus, the ability of the lead-tolerant isolates to transform lead ions into stable and highly insoluble lead minerals make them potentially useful for immobilization of lead in mining waste.

  14. Lead contamination and transfer in urban environmental compartments analyzed by lead levels and isotopic compositions

    International Nuclear Information System (INIS)

    Hu, Xin; Sun, Yuanyuan; Ding, Zhuhong; Zhang, Yun; Wu, Jichun; Lian, Hongzhen; Wang, Tijian

    2014-01-01

    Lead levels and isotopic compositions in atmospheric particles (TSP and PM 2.5 ), street dust and surface soil collected from Nanjing, a mega city in China, were analyzed to investigate the contamination and the transfer of lead in urban environmental compartments. The lead contents in TSP and PM 2.5 are significantly higher than them in the surface soil and street dust (p  206 Pb/ 207 Pb vs. 208 Pb/ 206 Pb and 206 Pb/ 207 Pb vs. 1/Pb imply that the street dust and atmospheric particles (TSP and PM 2.5 ) have very similar lead sources. Coal emissions and smelting activities may be the important lead sources for street dust and atmospheric particles (TSP and PM 2.5 ), while the deposition of airborne lead is an important lead source for urban surface soil. - Highlights: • Lead levels and isotope ratios in atmospheric particles, street dust and surface soil. • Significant enrichment of lead in atmospheric particles was observed. • Street dust and atmospheric particles have similar lead sources. • Endmembers of soil lead differ from street dust and atmospheric particles. • Airborne lead poses the main risks to unban environmental quality. - Transfer of airborne particle bound lead into street dust and surface soil in unban environmental based on lead levels and isotopic compositions

  15. Lead user projects in practice

    DEFF Research Database (Denmark)

    Brem, Alexander; Gutstein, Adele

    2018-01-01

    Earlier research on the lead user method is focused on individual case studies and how the method was applied in a specific context. In this paper, we take a broader approach, analyzing a sample of 24 lead user projects, which included working with 188 lead users. These projects were analyzed...

  16. Current density waves in open mesoscopic rings driven by time-periodic magnetic fluxes

    International Nuclear Information System (INIS)

    Yan Conghua; Wei Lianfu

    2010-01-01

    Quantum coherent transport through open mesoscopic Aharonov-Bohm rings (driven by static fluxes) have been studied extensively. Here, by using quantum waveguide theory and the Floquet theorem we investigate the quantum transport of electrons along an open mesoscopic ring threaded by a time-periodic magnetic flux. We predicate that current density waves could be excited along such an open ring. As a consequence, a net current could be generated along the lead with only one reservoir, if the lead additionally connects to such a normal-metal loop driven by the time-dependent flux. These phenomena could be explained by photon-assisted processes, due to the interaction between the transported electrons and the applied oscillating external fields. We also discuss how the time-average currents (along the ring and the lead) depend on the amplitude and frequency of the applied oscillating fluxes.

  17. Right ventricular pacemaker lead position is associated with differences in long-term outcomes and complications.

    Science.gov (United States)

    Witt, Chance M; Lenz, Charles J; Shih, Henry H; Ebrille, Elisa; Rosenbaum, Andrew N; van Zyl, Martin; Aung, Htin; Manocha, Kevin K; Deshmukh, Abhishek J; Hodge, David O; Mulpuru, Siva K; Cha, Yong-Mei; Espinosa, Raul E; Asirvatham, Samuel J; Mcleod, Christopher J

    2017-08-01

    Cardiac pacing from the right ventricular apex is associated with detrimental long-term effects and nonapical pacing locations may be associated with improved outcomes. There is little data regarding complications with nonapical lead positions. The aim of this study was to assess long-term outcomes and lead-related complications associated with differing ventricular lead tip position. All adult patients who underwent dual-chamber pacemaker implantation from 2004 to 2014 were included if they had postprocedure chest radiographs amenable to lead position determination. Long-term outcomes and lead-related complication rates were recorded. These were compared at 5 years between: (1) apical and septal leads, (2) apical and nonseptal nonapical (NSNA), and (3) apical and septal with >40% ventricular pacing. We retrospectively evaluated 3,450 patients, which included 238 with a septal position and 733 with NSNA lead positions. Septal lead position was associated with a lower mortality compared to apical leads (24% vs. 31%, P = 0.02). In patients with greater than 40% pacing, septal leads were associated with significantly higher rates of incident atrial fibrillation compared to apical leads (49% vs. 34%, P = 0.04). NSNA positions were associated with a significantly higher rate of lead dislodgement (4% vs. 2%, P = 0.005) and need for revision (8% vs. 5%, P = 0.005). Septal pacemaker lead position is associated with a lower mortality compared to apically placed leads, but a higher incidence of atrial fibrillation with higher percentage ventricular pacing. NSNA lead locations are associated with more complications and should be avoided. © 2017 Wiley Periodicals, Inc.

  18. Temporal dynamics of airborne lead-210 in Missouri (USA): implications for geochronological methods

    International Nuclear Information System (INIS)

    Sheets, R.W.; Lawrence, A.E.

    1999-01-01

    Lead-210 ( 210 Pb) deposited from the atmosphere is used in the dating of certain geological materials such as glacial ice and lacustrine sediments, but its long-term atmospheric behavior has been little studied. The present investigation reports measurements of airborne 210 Pb at 21 monitoring stations in Springfield, Missouri, during 1975-1995. Seasonal and diurnal patterns of atmospheric concentrations are established, and the mean annual concentrations of 210 Pb in ground level air during the 20-year period are examined. Although airborne 210 Pb concentrations are found to vary diurnally and seasonally, mean annual concentrations in southwest Missouri have remained relatively constant during this time period. This finding is important for geochronological methods that assume a constant 210 Pb flux from the atmosphere. (orig.)

  19. Periodic auroral forms and geomagnetic field oscillations in the 1400 MLT region

    International Nuclear Information System (INIS)

    Potemra, T.A.; Vo, H.; Venkatesan, D.; Cogger, L.L.; Erlandson, R.E.; Zanetti, L.J.; Bythrow, P.F.; Anderson, B.J.

    1990-01-01

    The UV images obtained with the Viking satellite often show bright features which resemble beads or pearls aligned in the east-west direction between noon and 1800 MLT. Viking acquired a series of 25 UV images during a 28-min period on July 29, 1986, which showed a distinct series of periodic bright features in this region. Magnetic field and hot plasma measurements obtained by Viking confirm that the UV emissions are colocated with the field line projection of an upward-flowing region 1 Birkeland current and precipitating energetic (∼200 eV) electrons. The magnetic field and electric field measurements show transverse oscillations with a nearly constant period of about 3.5 min from 67 degree invariant latitude equatorward up to the location of the large-scale Birkeland current system near 76 degree invariant latitude. The electric field oscillations lead the magnetic field oscillations by about a quarter-period. The authors interpret the observed oscillations as standing Alfven waves driven at a frequency near the local resonance frequency by a large-scale wave in the boundary layer. They propose that the energy flux of the precipitating low-energy electrons in this afternoon region is modulated by this boundary wave and produces the periodic UV emission features. The results of this study support the view that large-scale oscillations of magnetospheric boundaries, possibly associated with the Kelvin-Helmholtz instability, can modulate currents, particles, and auroral forms

  20. Does centennial morphodynamic evolution lead to higher channel efficiency in San Pablo Bay, California?

    Science.gov (United States)

    van der Wegen, M.; Jaffe, B.E.; Barnard, P.L.; Jaffee, B.E.; Schoellhamer, D.H.

    2013-01-01

    Measured bathymetries on 30 year interval over the past 150 years show that San Pablo Bay experienced periods of considerable deposition followed by periods of net erosion. However, the main channel in San Pablo Bay has continuously narrowed. The underlying mechanisms and consequences of this tidal channel evolution are not well understood. The central question of this study is whether tidal channels evolve towards a geometry that leads to more efficient hydraulic conveyance and sediment throughput. We applied a hydrodynamic process-based, numerical model (Delft3D), which was run on 5 San Pablo Bay bathymetries measured between 1856 and 1983. Model results shows increasing energy dissipation levels for lower water flows leading to an approximately 15% lower efficiency in 1983 compared to 1856. During the same period the relative seaward sediment throughput through the San Pablo Bay main channel increased by 10%. A probable explanation is that San Pablo Bay is still affected by the excessive historic sediment supply. Sea level rise and Delta surface water area variations over 150 years have limited effect on the model results. With expected lower sediment concentrations in the watershed and less impact of wind waves due to erosion of the shallow flats, it is possible that energy dissipations levels will decrease again in future decades. Our study suggests that the morphodynamic adaptation time scale to excessive variations in sediment supply to estuaries may be on the order of centuries.