WorldWideScience

Sample records for scientific subject profile

  1. Can scientific journals be classified based on their citation profiles?

    Directory of Open Access Journals (Sweden)

    Sayed-Amir Marashi

    2015-03-01

    Full Text Available Classification of scientific publications is of great importance in biomedical research evaluation. However, accurate classification of research publications is challenging and normally is performed in a rather subjective way. In the present paper, we propose to classify biomedical publications into superfamilies, by analysing their citation profiles, i.e. the location of citations in the structure of citing articles. Such a classification may help authors to find the appropriate biomedical journal for publication, may make journal comparisons more rational, and may even help planners to better track the consequences of their policies on biomedical research.

  2. The profile of high school students’ scientific literacy on fluid dynamics

    Science.gov (United States)

    Parno; Yuliati, L.; Munfaridah, N.

    2018-05-01

    This study aims to describe the profile of scientific literacy of high school students on Fluid Dynamics materials. Scientific literacy is one of the ability to solve daily problems in accordance with the context of materials related to science and technology. The study was conducted on 90 high school students in Sumbawa using survey design. Data were collected using an instrument of scientific literacy for high school students on dynamic fluid materials. Data analysis was conducted descriptively to determine the students’ profile of scientific literacy. The results showed that high school students’ scientific literacy on Fluid Dynamics materials was in the low category. The highest average is obtained on indicators of scientific literacy i.e. the ability to interpret data and scientific evidence. The ability of scientific literacy is related to the mastery of concepts and learning experienced by students, therefore it is necessary to use learning that can trace this ability such as Science, Technology, Engineering, and Mathematics (STEM).

  3. Putting a spin on circulating reference, or how to rediscover the scientific subject.

    Science.gov (United States)

    Kochan, Jeff

    2015-02-01

    Bruno Latour claims to have shown that a Kantian model of knowledge, which he describes as seeking to unite a disembodied transcendental subject with an inaccessible thing-in-itself, is dramatically falsified by empirical studies of science in action. Instead, Latour puts central emphasis on scientific practice, and replaces this Kantian model with a model of "circulating reference." Unfortunately, Latour's alternative schematic leaves out the scientific subject. I repair this oversight through a simple mechanical procedure. By putting a slight spin on Latour's diagrammatic representation of his theory, I discover a new space for a post-Kantian scientific subject, a subject brilliantly described by Ludwik Fleck. The neglected subjectivities and ceaseless practices of science are thus re-united. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. [Gender and health: profile and trends of the scientific production in Brazil].

    Science.gov (United States)

    Aquino, Estela M L

    2006-08-01

    The differences in health between men and women have been object of great interest, but interpretations tend to be naturalized and essentialists. Gender-oriented studies have criticized this literature and offered new analythical alternatives. The present study was intended to describe the profile and trends of scientific production on gender and health in Brazil. Data sources comprised the Research Groups Directory of Conselho Nacional de Desenvolvimento Científico e Tecnológico (National Research Council), CAPES (Coordination for the Improvement of Higher Education Personnel) Thesis Bank, and four journals available in SciELO--Scientific Eletronic Library Online. Fifty-one groups with at least one line of research in the subject were identified, with regional and institutional concentrations. The results confirmed the marked growth of scientific production in this field as 98 master and 42 doctoral dissertations and 665 articles on gender and health were retrieved. Women authored 86.0% and 89.0% of doctoral and master dissertations respectively, and 70.5% of the articles. Most were published in the 2000s when diversification of the studied topics was also seen. The studied subjects can be divided into five subgroups: reproduction and contraception; gender and violence; sexuality and health with emphasis on STD/AIDS; work and health, including domestic and night work; other emergent or less explored topics. There are major political, epistemological and methodological challenges for strengthening these advancements. The gender perspective offers possibilities for enlightment of theoretical dilemmas in public health. Furthermore, it can be added to other intellectual and political efforts towards understanding health and its determinants and fighting against inequalities and for social justice.

  5. Profile and scientific production of CNPq researchers in cardiology.

    Science.gov (United States)

    Oliveira, Eduardo Araujo de; Ribeiro, Antonio Luiz Pinho; Quirino, Isabel Gomes; Oliveira, Maria Christina Lopes; Martelli, Daniella Reis; Lima, Leonardo Santos; Colosimo, Enrico Antonio; Lopes, Thais Junqueira; Silva, Ana Cristina Simões; Martelli, Hercílio

    2011-09-01

    Systematic assessments of the scientific production can optimize resource allocation and increase research productivity in Brazil. The aim of this study was to evaluate the profile and scientific production of researchers in the field of Cardiology who have fellowship in Medicine provided by the Conselho Nacional de Desenvolvimento Científico e Tecnológico. The curriculum Lattes of 33 researchers with active fellowships from 2006 to 2008 were included in the analysis. The variables of interest were: gender, affiliation, tutoring of undergraduate, masters and PhD students, and scientific production and its impact. : There was predominance of males (72.7%) and of fellowship level 2 (56.4%). Three states of the Federation were responsible for 94% of the researchers: SP (28; 71.8%), RS (4; 10.3%), e RJ (3; 9.1%). Four institutions are responsible for about 82% of researchers: USP (13; 39.4%), UNESP (5; 15.2%), UFRGS (4; 12.1%) e UNIFESP (3; 9.1%). During all academic careers, the researchers published 2.958 journal articles, with a mean of 89 articles per researcher. Of total, 55% and 75% were indexed at Web of Science and Scopus databases, respectively. The researchers received a total of 19648 citations at the database Web of Science, with a median of 330 citations per researcher (IQ = 198-706). The average number of citations per article was 13.5 citations (SD = 11.6). Our study has shown that researchers in the field of cardiology have a relevant scientific production. The knowledge of the profile of researchers in the field of Cardiology will probably enable effective strategies to qualitatively improve the scientific output of Brazilian researchers.

  6. The Scientific Theory Profile: A Philosophy of Science Model for Science Teachers.

    Science.gov (United States)

    Loving, Cathleen

    The model developed for use with science teachers--called the Scientific Theory Profile--consists of placing three well-known philosophers of science on a grid, with the x-axis being their methods for judging theories (rational vs. natural) and the y-axis being their views on scientific theories representing the Truth versus mere models of what…

  7. Scientific and General Subject Classifications in the Digital World

    CERN Document Server

    De Robbio, Antonella; Marini, A

    2001-01-01

    In the present work we discuss opportunities, problems, tools and techniques encountered when interconnecting discipline-specific subject classifications, primarily organized as search devices in bibliographic databases, with general classifications originally devised for book shelving in public libraries. We first state the fundamental distinction between topical (or subject) classifications and object classifications. Then we trace the structural limitations that have constrained subject classifications since their library origins, and the devices that were used to overcome the gap with genuine knowledge representation. After recalling some general notions on structure, dynamics and interferences of subject classifications and of the objects they refer to, we sketch a synthetic overview on discipline-specific classifications in Mathematics, Computing and Physics, on one hand, and on general classifications on the other. In this setting we present The Scientific Classifications Page, which collects groups of...

  8. Differentiation of salivary bacterial profiles of subjects with periodontitis and dental caries

    DEFF Research Database (Denmark)

    Belstrøm, Daniel; Fiehn, Nils-Erik; Nielsen, Claus H

    2015-01-01

    Bacterial profiles of saliva in subjects with periodontitis and dental caries have been demonstrated to differ from that of oral health. The aim of this comparative analysis of existing data generated by the Human Oral Microbe Identification Microarray (HOMIM) from 293 stimulated saliva samples...... was to compare bacterial profiles of saliva in subjects with periodontitis and dental caries....

  9. Scientific reasoning profile of junior secondary school students on the concept of static fluid

    Science.gov (United States)

    Mariana, N.; Siahaan, P.; Utari, S.

    2018-05-01

    Scientific reasoning is one of the most important ability. This study aims to determine the profile of scientific reasoning of junior high school students about the concept of static fluid. This research uses a descriptive method with a quantitative approach to get an idea about the scientific reasoning of One Roof Junior Secondary School Student Kotabaru Reteh in Riau. The technique of collecting data is done by test of scientific reasoning. Scientific reasoning capability refers to Furtak’s EBR (Evidence Based Reasoning) scientific reasoning indicator that contains the components of claims, data, evidence, and rules. The result obtained on each element of scientific reasoning is 35% claim, 23% data, 21% evidence and 17% rule. The conclusions of this research that scientific reasoning of Satu Atap Junior Secondary School student Kotabaru Reteh, Riau Province still in the low category.

  10. Recognition and development of "educational technology" as a scientific field and school subject

    Directory of Open Access Journals (Sweden)

    Danilović Mirčeta S.

    2004-01-01

    Full Text Available The paper explores the process of development, establishment and recognition of "educational technology" as an independent scientific field and a separate teaching subject at universities. The paper points to: (a the problems that this field deals with or should deal with, (b knowledge needed for the profession of "educational technologist", (c various scientific institutions across the world involved in educational technology, (d scientific journals treating issues of modern educational technology, (e the authors i.e. psychologists and educators who developed and formulated the basic principles of this scientific field, (f educational features and potentials of educational technologies. Emphasis is placed on the role and importance of AV technology in developing, establishing and recognition of educational technology, and it is also pointed out that AV technology i.e. AV teaching aids and a movement for visualization of teaching were its forerunners and crucial factors for its establishing and developing into an independent area of teaching i.e. school subject. In summary it is stressed that educational technology provides for the execution of instruction through emission transmission, selection, coding, decoding, reception, memorization transformation of all types of pieces of information in teaching.

  11. Profile and scientific production of Brazilian National Council of Technological and Scientific Development researchers in Pediatrics.

    Science.gov (United States)

    Oliveira, Maria Christina L; Martelli, Daniella Reis B; Pinheiro, Sergio Veloso; Miranda, Debora Marques; Quirino, Isabel Gomes; Leite, Barbara Gusmão L; Colosimo, Enrico Antonio; e Silva, Ana Cristina S; Martelli-Júnior, Hercílio; Oliveira, Eduardo Araujo

    2013-09-01

    To evaluate the profile and the scientific production of researchers in Pediatrics with scholarship from the National Counsel of Technological and Scientific Development. The Lattes curricula of 34 researchers in Pediatrics with active scholarships, from 2006 to 2008 were included in the analysis. The variables of interest were: gender, affiliation, time since PHD, tutoring of undergraduate students, mentorship of masters and doctors, scientific production and the papers' impact. In a total of 411 researchers in Medicine, 34 (8%) belonged to Pediatrics. Males (77%) and scholars in the category 2 of productivity (62%) prevailed. Three states of Brazil were responsible for approximately 90% of the researchers: São Paulo (53%), Minas Gerais (21%), and Rio Grande do Sul (15%). During their academic career, the Pediatrics researchers have published 3,122 articles with a median of 89 articles per researcher (interquartile range - IQ=51-119). Of the total, 40 and 59% articles were indexed in the Web of Science and Scopus databases, respectively. The Pediatrics researchers have published papers in 599 journals with a median impact factor of 2.35 (IQ=1.37-3.73) for the 323 indexed journals. The Pediatrics researchers have a relevant scientific output from the quantity point of the view, but there is a need to improve quality.

  12. Profile and scientific production of CNPq researchers in Nephrology and Urology.

    Science.gov (United States)

    Oliveira, Eduardo A; Pécoits-Filho, Roberto; Quirino, Isabel G; Oliveira, Maria Christina; Martelli, Daniela Reis; Lima, Leonardo S; Martelli, Hercílio

    2011-03-01

    This study aimed at evaluating the profile and scientific production of researchers in Nephrology and Urology, receiving grants in the area of Clinical Medicine from the Brazilian National Research Council. The standardized online curriculum vitae (Curriculum Lattes) of 39 researchers in Medicine receiving grants in the 2006-2008 triennium were included in the analysis. The variables analyzed were: gender, affiliation, time from completion of the PhD program, scientific production, and supervision of undergraduate students, and master's and PhD programs. Males (74.4%) and category 2 grants (56.4%) predominated. The following three Brazilian states are responsible for 90% of the researchers: São Paulo (28; 71.8%); Rio Grande do Sul (4; 10.3%); and Minas Gerais (3; 7.7%). Four institutions are responsible for 70% of the researchers: UNIFESP (14; 36%); USP (8; 20.5%); UFMG (3, 7.7%); and UNICAMP (3; 7.7%). Considering the academic career, the assessed researchers published 3,195 articles in medical journals, with a median of 75 articles per researcher (QI = 52-100). The researchers received a total of 25,923 citations at the database Web of Science®, with a median of 452 citations per researcher (QI = 161-927). The average number of citations per article was 13.8 citations (SD = 11.6). The Southeastern region of Brazil concentrates researchers in Nephrology and Urology. Our study has shown an increase in the scientific production of most researchers in the last five years. By knowing the profile of researchers in Nephrology and Urology, more effective strategies to encourage the scientific production and the demand for resources to finance research projects can be defined.

  13. Building a profile of subjective well-being for social media users.

    Science.gov (United States)

    Chen, Lushi; Gong, Tao; Kosinski, Michal; Stillwell, David; Davidson, Robert L

    2017-01-01

    Subjective well-being includes 'affect' and 'satisfaction with life' (SWL). This study proposes a unified approach to construct a profile of subjective well-being based on social media language in Facebook status updates. We apply sentiment analysis to generate users' affect scores, and train a random forest model to predict SWL using affect scores and other language features of the status updates. Results show that: the computer-selected features resemble the key predictors of SWL as identified in early studies; the machine-predicted SWL is moderately correlated with the self-reported SWL (r = 0.36, p subjective well-being profile can also reflect other psychological traits like depression (r = 0.24, p social media language.

  14. Analysis of students critical thinking skills in socio-scientific issues of biodiversity subject

    Science.gov (United States)

    Santika, A. R.; Purwianingsih, W.; Nuraeni, E.

    2018-05-01

    Critical thinking is a skills the which students should have in order to face 21st century demands. Critical thinking skills can help people in facing their daily problems, especially problems roommates relate to science. This research is aimed to analyze students critical thinking skills in socio-scientific issues of biodiversity subject. The method used in this research was descriptive method. The research subject is first-grade students’ in senior high school. The data collected by interview and open-ended question the which classified based on framework : (1) question at issue, (2) information (3) purpose (4) concepts (5) assumptions, (6) point of view, (7) interpretation and inference, and (8) implication and consequences, then it will be assessed by using rubrics. The result of the data showed students critical thinking skills in socio-scientific issues of biodiversity subject is in low and medium category. Therefore we need a learning activity that is able to develop student’s critical thinking skills, especially regarding issues of social science.

  15. Profile and scientific production of Brazilian National Council of Technological and Scientific Development researchers in Pediatrics

    Directory of Open Access Journals (Sweden)

    Maria Christina L. Oliveira

    2013-09-01

    Full Text Available OBJECTIVE: To evaluate the profile and the scientific production of researchers in Pediatrics with scholarship from the National Counsel of Technological and Scientific Development. METHODS: The Lattes curricula of 34 researchers in Pediatrics with active scholarships, from 2006 to 2008 were included in the analysis. The variables of interest were: gender, affiliation, time since PHD, tutoring of undergraduate students, mentorship of masters and doctors, scientific production and the papers' impact. RESULTS: In a total of 411 researchers in Medicine, 34 (8% belonged to Pediatrics. Males (77% and scholars in the category 2 of productivity (62% prevailed. Three states of Brazil were responsible for approximately 90% of the researchers: São Paulo (53%, Minas Gerais (21%, and Rio Grande do Sul (15%. During their academic career, the Pediatrics researchers have published 3,122 articles with a median of 89 articles per researcher (interquartile range - IQ=51-119. Of the total, 40 and 59% articles were indexed in the Web of Science and Scopus databases, respectively. The Pediatrics researchers have published papers in 599 journals with a median impact factor of 2.35 (IQ=1.37-3.73 for the 323 indexed journals. CONCLUSIONS: The Pediatrics researchers have a relevant scientific output from the quantity point of the view, but there is a need to improve quality.

  16. Teachers mathematical communication profile in explaining subject matter

    Science.gov (United States)

    Umami, Rohmatul; Budayasa, I. Ketut; Suwarsono, St.

    2017-12-01

    This study aimed to see a teachers mathematical communication profile in explaining a subject matter. It is a qualitative research. A high-school junior teacher (i.e., a teacher with 1- to 5-year experience) teaching mathematics at X-Social Class was selected as the subject of this study. The data was collected by observing the teachers mathematical communication in explaining a given material (i.e., the rule of sine) in class and an in-depth interview would be organized respectively. The result showed that the junior teacher explained the subject matter in systematic, complete, fluent, and centered manner. In this case, she began with reminding students on the previous material related to the current material to be learned, informing the current learning objectives, and finally delivering the subject matter. To support her explanation, the teacher also provided some related information, led the students attention into the given material by asking them particular related questions, and did not use any confusing terms. However, the study found that some of high-school teachers still used less appropriate language in explaining materials.

  17. Empirical Phenomenon, Subjective Construction And Ontological Trught: (An Analysis of Problems of Scientific Explanation and Critical Realism Approach

    Directory of Open Access Journals (Sweden)

    Faramarz Taghilou

    2014-12-01

    Full Text Available Both the positivist and negativist frameworks of explanation are common in this naturalist proposition that unlike the metaphysical philosophy, reality is embedded only in experimental level. Therefore, the scientific explanation of natural and social phenomenon should refer to this experimental level in order to be called meaningful, verifiable and scientific. But, the problem was always that the principle of causality as a necessary condition for every kind of scientific explanation is not logically deductible from induction in experimental level and remains as a metaphysical principle. The principle of experimental objectivity as a condition for the verifiability clause of scientific explanations could not be defended, because the experimentation was always embedded in subjectivity and theory. The Kantian idealists, in contrast, considering the scientific explanation as a mere representation of reality in subjective categories, could not justify the experimental knowledge of reality and the rationality for comparison among theories and paradigms. Critical Realism as an important approach in philosophy of science that relates to the works and thoughts of Roy Bhaskar tries to solve these problems by resorting to its principles of ontological realism, epistemological relativism, and judgmental rationality. Considering and analyzing the scientific explanation’s issues, we have focused here on the answers of the Critical Realism in this case. We will argue that how the Critical Realist interpretation of scientific explanation, the experimental phenomenon, and the subjective construction and ontological reality all reach to a logical coherence with each other.

  18. The scientific argumentation profile of physics teacher candidate in Surabaya

    Science.gov (United States)

    Ain, T. N.; Wibowo, H. A. C.; Rohman, A.; Deta, U. A.

    2018-03-01

    The ability of scientific argumentation is an essential factor that must be mastered by physics teacher candidate as a requirement in explaining good and accurate scientific concepts. In the process of arguing, students develop explanations or persuade colleagues to support their hypotheses, express doubts, ask questions, relate alternative answers, and confirm what is unknown to develop the ability to provide rational and scientific explanations. The design of this research is descriptive qualitative with the subject of research is 20 undergraduate students of Physics Education Department in Surabaya. The research instrument consists of four casuistic questions related to the concept of kinematics. The argumentation pattern of physics teacher candidate is coded using Toulmin's argumentation pattern. The results show that the student’s ability in providing scientific argument is at the level of providing claims with the support of a weak warrant. The students are not able to provide excellent rebuttals. In each case given, the student can give a good claim statement in answering the questions. However, the concept used to support the claim is not correct. This case causes the warrant used to support the claim is weak. Students also do not analyse other facts that affect the system. Students have not reached a higher level because the understanding of physics is not deep enough.

  19. Lipid Profile Pattern amongst Type 2 DM subjects with Erectile ...

    African Journals Online (AJOL)

    Objective:Dyslipidaemia in patientswith diabetesmellitus leads to atherosclerosis and this contributes to erectile dysfunction (ED). This study set out to characterize the lipid profile pattern in diabetic patients with erectile dysfunction. Subject andMethods:Aprospective, cross sectional study carried out at the diabetes clinic of ...

  20. Motivational profiles in table tennis players: Relations with performance anxiety and subjective vitality.

    Science.gov (United States)

    Chu, Tsz Lun Alan; Zhang, Tao; Hung, Tsung-Min

    2018-06-27

    Research has suggested the need to use a person-centred approach to examine multidimensionality of motivation. Guided by self-determination theory (Deci & Ryan, 1985), the primary aim of the present study was to examine the motivational profiles in table tennis players and their composition by gender, country, training status, and competition levels (from recreational to international). The secondary aim was to examine the differences in performance anxiety and subjective vitality across the motivational profiles. Participants were 281 table tennis players from multiple countries, mostly the U.S. and China. Hierarchical and nonhierarchical cluster analyses were conducted and showed three motivational profiles with distinct quantity and quality: "low", "controlled", and "self-determined". Chi-square tests of independence demonstrated significant differences in their cluster membership by country, formal training with a coach, and competition levels, but not gender. MANCOVA results indicated differences in performance anxiety and subjective vitality across the motivational profiles, in which the controlled profile had the greatest anxiety symptoms. These differences are attributed to the quality over quantity of motivation, which have meaningful implications for table tennis coaches and sport psychology consultants to diagnose and intervene with players in order to reduce their performance anxiety and improve their well-being.

  1. The laureate as celebrity genius: How Scientific American's John Horgan profiled Nobel Prize winners.

    Science.gov (United States)

    Fahy, Declan

    2018-05-01

    When scientists become Nobel laureates, they become famous in science and public life, but few studies have examined the nature of their scientific celebrity. This article examines how Scientific American portrayed laureates in order to identify and explain core features of Nobel fame. It examines the portrayals of seven laureates - Francis Crick, Linus Pauling, Hans Bethe, Murray Gell-Mann, Brian Josephson, Philip Anderson and Subrahmanyan Chandrasekhar - in magazine profiles written between 1992 and 1995 by science writer John Horgan. Its textual analysis finds the scientists are portrayed as combining the sociological characteristics of genius, including enormous productivity and lasting impact, with the representational characteristics of celebrities, such as the merging of public and private lives. Their form of scientific celebrity is grounded in their field-changing research, which is presented as a product of their idiosyncratic personalities. Nobel science is presented as knowledge created by an ultra-elite of exceptional individuals.

  2. Profile of Brazilian scientific production on A/H1N1 pandemic influenza.

    Science.gov (United States)

    Luchs, Adriana

    2012-06-01

    In the last few years, bibliometric studies have proliferated, seeking to provide data on world research. This study analyzes the profile of the Brazilian scientific production in the A (H1N1) influenza field between 2009 and 2011. The research was conducted in MEDLINE, SciELO and LILACS databases, selecting papers in which the term "H1N1" and "Brazil" were defined as the main topics. The data were analyzed taking into consideration the Brazilian state and institution in which the articles were produced, the impact factor of the journal and the language. The research revealed 40 documents (27 from MEDLINE, 16 from SciELO and 24 from LILACS). The journal impact factor ranged from 0.0977 to 8.1230. A similar amount of articles were written in English and Portuguese and São Paulo was the most productive state in the country, with 95% of the Brazilian production originating from the Southern and Southeastern regions. Linguistic data indicate that previous efforts made in order to improve the scientific production of Brazilian researchers making their observations attain a broader scientific audience produced results. It is necessary to assess the scientific studies, especially those conducted with public funds, in order to ensure that the results will benefit society.

  3. Developing resident learning profiles: Do scientific evidence epistemology beliefs, EBM self-efficacy beliefs and EBM skills matter?

    Science.gov (United States)

    Robert, Nancy J.

    This study investigated resident scientific evidence epistemology beliefs, evidence based medicine (EBM) self-efficacy beliefs, and EBM skills. A convenience sample of fifty-one residents located in six U.S. based residency programs completed an online instrument. Hofer's epistemology survey questionnaire was modified to test responses based on four types of scientific evidence encountered in medical practice (Clinical Trial Phase 1, Clinical Trial Phase 3, Meta-analysis and Qualitative). It was hypothesized that epistemology beliefs would differ based on the type of scientific evidence considered. A principal components analysis produced a two factor solution that was significant across type of scientific evidence suggesting that when evaluating epistemology beliefs context does matter. Factor 1 is related to the certainty of research methods and the certainty of medical conclusions and factor 2 denotes medical justification. For each type of scientific evidence, both factors differed on questions comprising the factor structure with significant differences found for the factor 1 and 2 questions. A justification belief case problem using checklist format was triangulated with the survey results, and as predicted the survey and checklist justification z scores indicated no significant differences, and two new justification themes emerged. Modified versions of Finney and Schraw's statistical self-efficacy and skill instruments produced expected significant EBM score correlations with unexpected results indicating that the number of EBM and statistics courses are not significant for EBM self-efficacy and skill scores. The study results were applied to the construction of a learning profile that provided residents belief and skill feedback specific to individual learning needs. The learning profile design incorporated core values related to 'Believer' populations that focus on art, harmony, tact and diplomacy. Future research recommendations include testing context

  4. Dietary Pattern and Macronutrients Profile on the Variation of Inflammatory Biomarkers: Scientific Update.

    Science.gov (United States)

    Silveira, Brenda Kelly Souza; Oliveira, Thatianne Moreira Silva; Andrade, Patrícia Amaro; Hermsdorff, Helen Hermana Miranda; Rosa, Carla de Oliveira Barbosa; Franceschini, Sylvia do Carmo Castro

    2018-01-01

    It is known that the dietary pattern and macronutrients profile may influence the expression and secretion of inflammatory biomarkers, and the low-grade inflammation is associated with the manifestation of noncommunicable chronic diseases. Therefore, this review aimed to present and discuss the role of dietary patterns and macronutrients on the variation of inflammatory markers related to NCD risk. Scientific evidences within the last five years based on clinical trials, case-controls, cohorts, and cross-sectional studies indicate that normocaloric, carbohydrate-moderated, low-glycemic index, protein-moderated, monounsaturated and polyunsaturated fatty acid-rich, omega-3, and low-saturated fat diets display positive effects on the inflammatory state, both in healthy individuals and in those with cardiovascular risk, although the second group seems to benefit more from changes in the dietary profile.

  5. ON THE APPROACH TO SCIENTIFIC PUBLICATIONS VISIBILITY MAXIMIZATION BY THE SCIENTIFIC SOCIAL NETWORKS USAGE

    Directory of Open Access Journals (Sweden)

    A. V. Semenets

    2015-12-01

    3 Research results. Data integration of the user profiles of the scientific social networksThe maximization of visibility and bibliometrics citation increasing of the scientific papers initiated by the given above approach is discussed. The detailed strategy of the user profiles bibliometrics data integration through the scientific social networks is proposed. The role and ways to receiving of the Altmetric rating indices are mentioned.

  6. On a popular myth: “Scientific research cannot be subject to quality management”. Think again! Who says it cannot be?

    CSIR Research Space (South Africa)

    Theron, B

    2012-07-01

    Full Text Available In many scientific research environments the popular belief seems to be that scientific research cannot be subject to so-called “quality” management, at least not down to the research operational level. Examples of popular arguments behind...

  7. Building a profile of subjective well-being for social media users

    Science.gov (United States)

    Kosinski, Michal; Stillwell, David; Davidson, Robert L.

    2017-01-01

    Subjective well-being includes ‘affect’ and ‘satisfaction with life’ (SWL). This study proposes a unified approach to construct a profile of subjective well-being based on social media language in Facebook status updates. We apply sentiment analysis to generate users’ affect scores, and train a random forest model to predict SWL using affect scores and other language features of the status updates. Results show that: the computer-selected features resemble the key predictors of SWL as identified in early studies; the machine-predicted SWL is moderately correlated with the self-reported SWL (r = 0.36, p social media language. PMID:29135991

  8. Gastrointestinal pH profile in subjects with irritable bowel syndrome.

    Science.gov (United States)

    Lalezari, David

    2012-01-01

    To investigate the small bowel pH profile and small intestine transit time (SITT) in healthy controls and patients with irritable bowel syndrome (IBS). Nine IBS patients (3 males, mean age 35 yr) and 10 healthy subjects (6 males, mean age 33 yr) were studied. Intestinal pH profile and SITT were assessed by a wireless motility pH and pressure capsule (Smart Pill). Mean pH values were measured in the small intestine (SI) and compared both within and between groups. Data presented as mean or median, ANOVA, P <0.05 for significance. We found the pH for the first (Q1), second (Q2), third (Q3), and fourth quartile (Q4) of the SI in healthy versus IBS patients was 5.608 ± 0.491 vs. 5.667 ± 0.297, 6.200 ± 0.328 vs. 6.168 ± 0.288, 6.679 ± 0.316 vs. 6.741 ± 0.322, and 6.884 ± 0.200 vs. 6.899 ± 0.303, respectively. We found no significant group difference in pH per quartile (P=0.7979). The proximal SI was significantly more acidic, compared to distal segments, in both healthy subjects and IBS patients (P<0.0001). We found no significant difference in the measured SITT between IBS and control groups with a mean SITT of 218.56 ± 59.60 min and 199.20 ± 82.31 min, respectively (P=0.55). This study shows the presence of a gradient of pH along the SI, in both IBS and healthy subjects, the distal being less acidic. These finding may be of importance in small bowel homeostasis.

  9. Cigarette smoking substantially alters plasma microRNA profiles in healthy subjects

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, Kei; Yokota, Shin-ichi; Tatsumi, Naoyuki; Fukami, Tatsuki; Yokoi, Tsuyoshi; Nakajima, Miki, E-mail: nmiki@p.kanazawa-u.ac.jp

    2013-10-01

    Circulating microRNAs (miRNAs) are receiving attention as potential biomarkers of various diseases, including cancers, chronic obstructive pulmonary disease, and cardiovascular disease. However, it is unknown whether the levels of circulating miRNAs in a healthy subject might vary with external factors in daily life. In this study, we investigated whether cigarette smoking, a habit that has spread throughout the world and is a risk factor for various diseases, affects plasma miRNA profiles. We determined the profiles of 11 smokers and 7 non-smokers by TaqMan MicroRNA array analysis. A larger number of miRNAs were detected in smokers than in non-smokers, and the plasma levels of two-thirds of the detected miRNAs (43 miRNAs) were significantly higher in smokers than in non-smokers. A principal component analysis of the plasma miRNA profiles clearly separated smokers and non-smokers. Twenty-four of the miRNAs were previously reported to be potential biomarkers of disease, suggesting the possibility that smoking status might interfere with the diagnosis of disease. Interestingly, we found that quitting smoking altered the plasma miRNA profiles to resemble those of non-smokers. These results suggested that the differences in the plasma miRNA profiles between smokers and non-smokers could be attributed to cigarette smoking. In addition, we found that an acute exposure of ex-smokers to cigarette smoke (smoking one cigarette) did not cause a dramatic change in the plasma miRNA profile. In conclusion, we found that repeated cigarette smoking substantially alters the plasma miRNA profile, interfering with the diagnosis of disease or signaling potential smoking-related diseases. - Highlights: • Plasma miRNA profiles were unambiguously different between smokers and non-smokers. • Smoking status might interfere with the diagnosis of disease using plasma miRNAs. • Changes of plasma miRNA profiles may be a signal of smoking-related diseases.

  10. Cigarette smoking substantially alters plasma microRNA profiles in healthy subjects

    International Nuclear Information System (INIS)

    Takahashi, Kei; Yokota, Shin-ichi; Tatsumi, Naoyuki; Fukami, Tatsuki; Yokoi, Tsuyoshi; Nakajima, Miki

    2013-01-01

    Circulating microRNAs (miRNAs) are receiving attention as potential biomarkers of various diseases, including cancers, chronic obstructive pulmonary disease, and cardiovascular disease. However, it is unknown whether the levels of circulating miRNAs in a healthy subject might vary with external factors in daily life. In this study, we investigated whether cigarette smoking, a habit that has spread throughout the world and is a risk factor for various diseases, affects plasma miRNA profiles. We determined the profiles of 11 smokers and 7 non-smokers by TaqMan MicroRNA array analysis. A larger number of miRNAs were detected in smokers than in non-smokers, and the plasma levels of two-thirds of the detected miRNAs (43 miRNAs) were significantly higher in smokers than in non-smokers. A principal component analysis of the plasma miRNA profiles clearly separated smokers and non-smokers. Twenty-four of the miRNAs were previously reported to be potential biomarkers of disease, suggesting the possibility that smoking status might interfere with the diagnosis of disease. Interestingly, we found that quitting smoking altered the plasma miRNA profiles to resemble those of non-smokers. These results suggested that the differences in the plasma miRNA profiles between smokers and non-smokers could be attributed to cigarette smoking. In addition, we found that an acute exposure of ex-smokers to cigarette smoke (smoking one cigarette) did not cause a dramatic change in the plasma miRNA profile. In conclusion, we found that repeated cigarette smoking substantially alters the plasma miRNA profile, interfering with the diagnosis of disease or signaling potential smoking-related diseases. - Highlights: • Plasma miRNA profiles were unambiguously different between smokers and non-smokers. • Smoking status might interfere with the diagnosis of disease using plasma miRNAs. • Changes of plasma miRNA profiles may be a signal of smoking-related diseases

  11. The Cardiovascular Function Profile and Physical Fitness in Overweight Subjects

    Science.gov (United States)

    Megawati, E. R.; Lubis, L. D.; Harahap, F. Y.

    2017-03-01

    Obesity in children and young adult is associated with cardiovascular risk in short term and long term. The aim of this study was to describe the profile of the cardiovascular functions parameters and physical fitness in overweight. This is an analytical observational study with cross sectional approach. The samples of this study were 85 randomly selected subjects aged 18 to 24 years with normoweight and body mass index <40. The parameters measures were body mass index (BMI), waist circumference (WC), waist-hip ratio (WHR), cardiovascular function parameters (resting pulse, blood pressure, and peak flow meter) and physical fitness parameters (VO2max dengan McArdle step test). The mean BMI was 24,53±4,929. The WC and WHR mean were 86,7±14,10 cms and 0,89±0,073 cm respectively. The mean of resting pulses were higher in normoweight subject (p=0,0209). The mean systole were lower in normoweight subject (p=0,0026). No differences VO2 max between groups (p=0,3888). The peak flow meter was higher in normoweight (p=0,0274). The result of this study indicate that heart rate, systole and peak flow meter are signifantly different between groups. The heart rate and the peak flow meter in the overweight subjects were lower meanwhile the systole blood pressure was higher compared to normoweight subjects.

  12. Circadian profile of cardiac autonomic nervous modulation in healthy subjects

    DEFF Research Database (Denmark)

    Bonnemeier, Hendrik; Richardt, Gert; Potratz, Jürgen

    2003-01-01

    UNLABELLED: Circadian Profile of Heart Rate Variability. INTRODUCTION: Although heart rate variability (HRV) has been established as a tool to study cardiac autonomic activity, almost no data are available on the circadian patterns of HRV in healthy subjects aged 20 to 70 years. METHODS AND RESULTS...... higher in men. Younger men also exhibited significantly higher values...... parasympathetic activity. The significant gender-related difference of HRV decreases with aging. These findings emphasize the need to determine age-, gender-, and nycthemeral-dependent normal ranges for HRV assessment....

  13. Student’s profile about science literacy in Surakarta

    Science.gov (United States)

    Nur’aini, D.; Rahardjo, S. B.; Elfi Susanti, V. H.

    2018-05-01

    This research was conducted to find out student’s initial profile of science literacy. The method used was descriptive with 46 students as subjects. The instrument used is science literacy question referring to PISA 2015. Data processing technique used are scoring on each question, changing the score values, grouping the level subjects obtain based on the value and conclusion. Competencies measure in this test are explaining scientific phenomena, interpretation of data and evidence scientifically, and evaluate and design scientific inquiry. The results of the three competencies are 30,87%, 40,20% and 24,90%. Achievement level of science literacy achieved by students in level 1 47,82%, level 2 33,82%, level 3 42,93%, level 4 26,50%, level 5 21,73%. Based on the result of research, it can be concluded that the ability of science literacy students in Surakarta relatively low.

  14. Sexual Consent as a Scientific Subject: A Literature Review

    Science.gov (United States)

    Fenner, Lydia

    2017-01-01

    Despite the presumed centrality of sexual consent to definitions of sexual violence, it remains an ambiguous and often unexamined concept both in lay and professional/scientific discourses. The following literature review of peer-reviewed research studying sexual consent as a scientific object will thematically present major findings from said…

  15. Metabolic profile of normal glucose-tolerant subjects with elevated 1-h plasma glucose values

    Directory of Open Access Journals (Sweden)

    Thyparambil Aravindakshan Pramodkumar

    2016-01-01

    Full Text Available Aim: The aim of this study was to compare the metabolic profiles of subjects with normal glucose tolerance (NGT with and without elevated 1-h postglucose (1HrPG values during an oral glucose tolerance test (OGTT. Methodology: The study group comprised 996 subjects without known diabetes seen at tertiary diabetes center between 2010 and 2014. NGT was defined as fasting plasma glucose <100 mg/dl (5.5 mmol/L and 2-h plasma glucose <140 mg/dl (7.8 mmol/L after an 82.5 g oral glucose (equivalent to 75 g of anhydrous glucose OGTT. Anthropometric measurements and biochemical investigations were done using standardized methods. The prevalence rate of generalized and central obesity, hypertension, dyslipidemia, and metabolic syndrome (MS was determined among the NGT subjects stratified based on their 1HrPG values as <143 mg/dl, ≥143-<155 mg/dl, and ≥155 mg/dl, after adjusting for age, sex, body mass index (BMI, waist circumference, alcohol consumption, smoking, and family history of diabetes. Results: The mean age of the 996 NGT subjects was 48 ± 12 years and 53.5% were male. The mean glycated hemoglobin for subjects with 1HrPG <143 mg/dl was 5.5%, for those with 1HrPG ≥143-<155 mg/dl, 5.6% and for those with 1HrPG ≥155 mg/dl, 5.7%. NGT subjects with 1HrPG ≥143-<155 mg/dl and ≥155 mg/dl had significantly higher BMI, waist circumference, systolic and diastolic blood pressure, triglyceride, total cholesterol/high-density lipoprotein (HDL ratio, triglyceride/HDL ratio, leukocyte count, and gamma glutamyl aminotransferase (P < 0.05 compared to subjects with 1HrPG <143 mg/dl. The odds ratio for MS for subjects with 1HrPG ≥143 mg/dl was 1.84 times higher compared to subjects with 1HrPG <143 mg/dl taken as the reference. Conclusion: NGT subjects with elevated 1HrPG values have a worse metabolic profile than those with normal 1HrPG during an OGTT.

  16. The effect of sauna bathing on lipid profile in young, physically active, male subjects

    OpenAIRE

    Dorota Gryka; Wanda Pilch; Marta Szarek; Zbigniew Szygula; Łukasz Tota

    2014-01-01

    Objectives: The aim of the study was to evaluate effects of Finnish sauna bathing on lipid profile in healthy, young men. Material and Methods: Sixteen male subjects (20–23 years) were subjected to 10 sauna bathing sessions in a Finnish sauna every 1 or 2 days. The mean sauna temperature was 90±2°C, while humidity was 5–16%. Each session consisted of three 15-minute parts and a 2-minute cool-down between them. The following measurements were taken before and after the sauna sessions: body mas...

  17. Brazilian scientific evidence on Fournier’s gangrene

    Directory of Open Access Journals (Sweden)

    Érick Igor dos Santos

    2015-02-01

    Full Text Available The objective of this study was to describe the Brazilian scientific reports published over the past twenty years on Fournier’s gangrene. It is an integrative review conducted through incursions in the LILACS, MEDLINE, BDENF and Coleciona SUS databases with the descriptor ‘Fournier’s Gangrene’. Texts published between January 1994 and July 2014, in Portuguese, and freely available online were selected. According to the 14 articles found, the main symptoms of Fournier’s gangrene include discomfort with painful sensations, high fever, edema, malaise, and sweating. In most cases erythema and blistering are observed, evolving into a wound. The clinical profile assists in the selection of empirical antimicrobial therapy even before the culture results. It was concluded that early diagnosis and appropriate and aggressive treatment are crucial in patient prognosis. There is still a shortage of Brazilian scientific production with a high power of evidence on the subject.

  18. Serological profile of incidentally detected asymptomatic HBsAg positive subjects (IDAHS)

    International Nuclear Information System (INIS)

    Khokhar, N.; Gill, M.L.

    2004-01-01

    Objective: To evaluate the serological profile of patients with incidentally detected positive hepatitis-B surface antigen (HBsAg) and to asses the risk factors. Design: An observational study. Place and Duration of Study: This study was conducted at Shifa International Hospital, Islamabad from 1999 to 2003. Patients and Methods: All patients who presented to gastroenterology clinic of Shifa Intentional Hospital, Islamabad with positive HBsAg, detected incidentally, were tested for alamine transaminase (ALT), hepatitis Beantigen (HBeAg) and in certain cases hepatitis-B virus DNA (HBV DNA) by polymerase chain reaction (PCR). Their risk factors for acquisition of infection were assessed with specific questions. Results: A total of 224 patients were examined. One hundred sixty-four (73.2%) were male and 60 (26.8%) female. Mean age of all the subjects was 32.45 plus minus 11.85 years. Out of 224 patients, 48 (21.4%) were positive for HBeAg and 176 (78.6%) were negative. Out of 48 subjects who were positive for HBeAg, 36 underwent HBV DNA determination and 32 (88.8%) were positive for HBV DNA. Out of 176 subjects who had negative HBeAg, 46 had elevated ALT and in those HBV DNA was performed and 14 had positive HBV DNA. Most common risk factors detected in these patients were intramuscular injections and surgery, however, in a large number, risk factors were unknown. Conclusion: Twenty-one percent asymptomatic subjects with positive HBsAg were found to be HBeAg positive. A large number of subjects with negative HBeAg had HBV DNA positive suggesting presence of precore mutants. Intramuscular injections and surgery were noted to be frequent risk factors in these subjects. (author)

  19. RUSSIAN LAW SUBJECTS

    Directory of Open Access Journals (Sweden)

    D.N. Bakhrakh

    2006-03-01

    Full Text Available The question about the subjects of law branches is concerning the number of most important and difficult in law science. Its right decision influences on the subject of law regulation, precise definition of addressees of law norms, the volume of their rights and duties, the limits of action of norms of Main part of the branch, its principles. Scientific investigations, dedicated to law subjects system, promote the development of recommendations for the legislative and law applying activity; they are needed for scientific work organization and student training, for preparing qualified lawyers.

  20. Microarray expression profiling of human dental pulp from single subject.

    Science.gov (United States)

    Tete, Stefano; Mastrangelo, Filiberto; Scioletti, Anna Paola; Tranasi, Michelangelo; Raicu, Florina; Paolantonio, Michele; Stuppia, Liborio; Vinci, Raffaele; Gherlone, Enrico; Ciampoli, Cristian; Sberna, Maria Teresa; Conti, Pio

    2008-01-01

    Microarray is a recently developed simultaneous analysis of expression patterns of thousand of genes. The aim of this research was to evaluate the expression profile of human healthy dental pulp in order to find the presence of genes activated and encoding for proteins involved in the physiological process of human dental pulp. We report data obtained by analyzing expression profiles of human tooth pulp from single subjects, using an approach based on the amplification of the total RNA. Experiments were performed on a high-density array able to analyse about 21,000 oligonucleotide sequences of about 70 bases in duplicate, using an approach based on the amplification of the total RNA from the pulp of a single tooth. Obtained data were analyzed using the S.A.M. system (Significance Analysis of Microarray) and genes were merged according to their molecular functions and biological process by the Onto-Express software. The microarray analysis revealed 362 genes with specific pulp expression. Genes showing significant high expression were classified in genes involved in tooth development, protoncogenes, genes of collagen, DNAse, Metallopeptidases and Growth factors. We report a microarray analysis, carried out by extraction of total RNA from specimens of healthy human dental pulp tissue. This approach represents a powerful tool in the study of human normal and pathological pulp, allowing minimization of the genetic variability due to the pooling of samples from different individuals.

  1. Establishing Scientific Discourse in Classroom Interaction Teacher Students' Orientation to Mundane versus Technical Talk in the School Subject Norwegian

    Science.gov (United States)

    Skovholt, Karianne

    2018-01-01

    This article reports a case study on classroom interaction in teacher education in Norway. It addresses how teacher students in the school subject Norwegian constitute scientific talk in a student-led discussion. First, the analysis reveals tension in the classroom conversation between "mundane talk"--that is, where students make claims…

  2. English in the nursing degree: a pending subject.

    Science.gov (United States)

    Camacho-Bejarano, Rafaela; Barquero-González, Ana; Mariscal-Crespo, María Isabel; Merino-Navarro, Dolores

    2013-01-01

    The new competence profile of nursing professionals, scientific and medical development, the free circulation of health professionals worldwide, and the increasing social and cultural diversity requires that nurses have specific abilities in spoken and written English. The objective of this research is to describe the characteristics of the English language training required for a Bachelors of Nursing in Spain. A descriptive cross-sectional observational study has been performed in forty-six Spanish universities that offer the Bachelor in nursing degree. In line with the directives of the European Higher Education Area, all universities contemplate the mandatory credit of a second language emphasizing English, although there is considerable variability in the emphasis: 39.4% do not include any English subject, and of the remaining 60.6% who do include it, 60% considered it an elective subject, 32.5% basic education, and 7.5% mandatory. The English training has different characteristics in each university, which implies a different commitment from each center for this learning. This fact questions the adequacy of the education in relation to the new competence profile required by the European Higher Education Area, which may adversely affect future professional development.

  3. The Effects of 6 Isocaloric Meals on Body Weight, Lipid Profiles, Leptin, and Adiponectin in Overweight Subjects (BMI > 25)

    OpenAIRE

    Zeynab Hatami Zargaran; Moosa Salehi; Seyed Taghi Heydari; Siavash Babajafari

    2014-01-01

    Background: It seems that meal frequency is negatively related to body weight, but the relationship between meal frequency and weight loss is not clearly known yet. Objectives: The present study aimed to investigate whether 6 isocaloric meals affected body weight, lipid profiles, leptin, and adiponectin in overweight subjects. Methods: The present randomized controlled trial was conducted on 90 overweight subjects in 3 months. The subjects were randomly divided into two groups. The co...

  4. The development of scientific literacy assessment to measure student’s scientific literacy skills in energy theme

    Science.gov (United States)

    Rusilowati, A.; Nugroho, S. E.; Susilowati, E. S. M.; Mustika, T.; Harfiyani, N.; Prabowo, H. T.

    2018-03-01

    The research were aimed to develop and find out of validity, reliability, characteristic of scientific literacy assessment, and find out of the profile of students’ scientific literacy skills in Energy themed. The research is conducted in 7th grade of Secondary School at Demak, Central of Java Indonesia. The research design used R&D (Research and Development). The results of the research showed that the scientific literacy assessment was valid and reliable with 0.68 value in the first try out and 0.73 value in the last try out. The characteristics of the scientific literacy assessment are the difficulty index and the discrimination power. The difficulty index and distinguishing are 56.25% easy, 31.25% medium, and 12.5% very difficult with good discrimination power. The proportion of category of scientific literacy as the body of knowledge, the science as a way of investigating, science as a way of thinking, and the interaction among science, environment, technology, and society was 37.5%:25%:18.75%:18.75%. The highest to the lowest profile of students’ scientific literacy skills at Secondary School Demak was 72% in the category of science as a way of thinking and the lowest was 59% in the category of science as the body of knowledge.

  5. Does creatine supplementation improve the plasma lipid profile in healthy male subjects undergoing aerobic training?

    Directory of Open Access Journals (Sweden)

    Scagliusi Fernanda B

    2008-10-01

    Full Text Available Abstract We aimed to investigate the effects of creatine (Cr supplementation on the plasma lipid profile in sedentary male subjects undergoing aerobic training. Methods Subjects (n = 22 were randomly divided into two groups and were allocated to receive treatment with either creatine monohydrate (CR (~20 g·day-1 for one week followed by ~10 g·day-1 for a further eleven weeks or placebo (PL (dextrose in a double blind fashion. All subjects undertook moderate intensity aerobic training during three 40-minute sessions per week, over 3 months. High-density lipoprotein cholesterol (HDL, low-density lipoprotein cholesterol (LDL, very low-density lipoprotein cholesterol (VLDL, total cholesterol (TC, triglyceride (TAG, fasting insulin and fasting glycemia were analyzed in plasma. Thereafter, the homeostasis model assessment (HOMA was calculated. Tests were performed at baseline (Pre and after four (Post 4, eight (Post 8 and twelve (Post 12 weeks. Results We observed main time effects in both groups for HDL (Post 4 versus Post 8; P = 0.01, TAG and VLDL (Pre versus Post 4 and Post 8; P = 0.02 and P = 0.01, respectively. However, no between group differences were noted in HDL, LDL, CT, VLDL and TAG. Additionally, fasting insulin, fasting glycemia and HOMA did not change significantly. Conclusion These findings suggest that Cr supplementation does not exert any additional effect on the improvement in the plasma lipid profile than aerobic training alone.

  6. Profile of the subjects with soft tissue injuries attended at an occupational health service and the RSI

    Directory of Open Access Journals (Sweden)

    Camila de Freitas

    2015-07-01

    Full Text Available Aim: To investigate the profile of subjects with soft tissue injuries attended at the Reference Center of Occupational Health – CEREST in the municipality of Santos, Sao Paulo state, in 2010, and the social insurance benefits granted.Materials and Methods: Analysis of medical records of the subjects assisted at CEREST in 2010, surveying data on gender, age, occupation, clinical diagnostics, clinical complaints, retirement, etc. The clinical diagnostics were categorized according to the International Classification of Diseases - ICD-10, subjects with soft tissue injuries were selected, and the diagnostics related to mental health disorders were registered. Data were recorded in Microsoft Excel spreadsheet and analyzed using statistical software R Development Core Team.Results: Of the 206 medical records analyzed, 18.0% (n=37 showed soft tissue injuries, 81.1% were female and 18.9% were male, and the subjects’ mean age was 43.24 years (SD=8.76. Subjects between 31 and 50 years old (70.2% were the most affected. The most affected occupations were cleaners, general service workers, and bank clerks. The most prevalent clinical diagnoses were synovitis and tenosynovitis, shoulder bursitis, and rotator cuff syndrome, with 62.2% of the subjects presenting more than one clinical diagnosis. 13.5% of the subjects also presented mental disorders. Association between retirement from work and the presence of soft tissue injury was observed (p=0.032. Only 13.5% of the diagnoses had some association with the work conditions.Conclusions: The general profile of the workers with soft tissue injuries was obtained: prevalence in women, diseases manifested in productive age, difficulty of association with work conditions, need for interdisciplinary interventions.

  7. Density profile and cholesterol concentration of serum lipoproteins in experimental animals and human subjects on hypercholesterolaemic diets

    NARCIS (Netherlands)

    Beynen, A.C.; Terpstra, A.H.M.

    1984-01-01

    1. 1. The density profile of Sudan black stained serum lipoproteins was studied in human subjects and various animal species on diets supplemented with cholesterol. 2. 2. In the animals studied (rabbits, calves, mice, chickens, rats and guinea-pigs), the feeding of cholesterol resulted in an

  8. Magic Graphical Symbols as Subject of Scientific Investigations

    Directory of Open Access Journals (Sweden)

    I. I. Miachikova

    2004-01-01

    Full Text Available The paper contains a short review of scientific insights about the essence of graphical symbols in the period of occult insight domination in science. It is shown that all the works of this period in respect of the investigated problem belong to the following three directions - religious, alchemical and nature-philosophical. Analysis of these works proves that rather high level of knowledge about esoteric of graphical symbols was achieved at that time.

  9. Thermomechanical response of a cross-ply titanium matrix composite subjected to a generic hypersonic flight profile

    International Nuclear Information System (INIS)

    Mirdamadi, M.; Johnson, W.S.

    1993-01-01

    Cross-ply laminate behavior of Ti-15V-3Cr-3AI-3Sn (Ti-15-3) matrix reinforced with continuous silicon-carbide fibers (SCS-6) subjected to a generic hypersonic flight profile was evaluated experimentally and analytically. Thermomechanical fatigue test techniques were developed to conduct a simulation of a generic hypersonic flight profile. A micromechanical analysis was used. The analysis predicts the stress-strain response of the laminate and of the constituents in each ply during thermal and mechanical cycling by using only constituent properties as input. The fiber was modeled as elastic with transverse orthotropic and temperature-dependent properties. The matrix was modeled using a thermoviscoplastic constitutive relation. The fiber transverse modulus was reduced in the analysis to simulate the fiber-matrix interface failure. Excellent correlation was found between measured and predicted laminate stress-strain response due to generic hypersonic flight profile when fiber debonding was modeled

  10. Influence of sarcopenia and functionality indicators on the frailty profile of community-dwelling elderly subjects: a cross-sectional study.

    Science.gov (United States)

    Viana, Joana U; Silva, Silvia L A; Torres, Juliana L; Dias, João M D; Pereira, Leani S M; Dias, Rosângela C

    2013-01-01

    Frailty and sarcopenia are frequent conditions in the elderly and are related to inactivity and functionality. However, little is known about the influence of the sarcopenia indicators on the frailty profile or their functional implications. To evaluate whether the indirect indicators of sarcopenia and functionality influence the frailty profile in elderly subjects. This was a cross-sectional study with 53 elderly subjects recruited by an active search in a secondary health care service. The indirect indicators of sarcopenia were body mass index (BMI), gait speed, Mini-Nutritional Assessment (MNA), Human Activity Profile (HAP), and handgrip strength. Frailty was characterized according to Fried's Frailty Phenotype. Functional capacity was assessed according to the Short Physical Performance Battery (SPPB). Physical activity level was assessed by HAP. Data were analyzed by analysis of variance (ANOVA) and multiple regression. Overall, 75.5% of the subjects were women, with a mean age of 76.72 (±5.89) years; 15.1% were frail and 54.7% pre-frail; and the level of physical activity was the most prevalent indicator of sarcopenia. Significant differences (psarcopenia indicators were associated with functional capacity and geriatric depression score. The level of physical activity and gait speed appeared to be the most relevant factors in the development of frailty in the study sample, which may have functional implications.

  11. Family, non-professional or informal caregivers: A review of terminology in scientific publications

    Directory of Open Access Journals (Sweden)

    María del Mar Molero Jurado

    2016-06-01

    Full Text Available Introduction: The figure of the caregiver of dependent persons is today the subject of scientific research in various disciplines in the health and social sciences. However, the terminology used to refer to the caregiver is often confusing, especially when they are not health professionals. Purpose: To analyze the terminology used to refer to the figure of the unpaid caregiver without technical training in scientific publications in recent years. Methods: A two-stage analysis was conducted: (1 review of publications in national and international databases in 1996-2005 and 2006-2016, and (2 review 2006-2016 using specific Dialnet database filters. Results: Despite the more frequent use of "family caregivers" (in Spanish and English in the publication titles, differences were observed in the use of other terms depending on the year of publication, the subject matter, type of journal or quality of the publication. Conclusion: The lack of agreement on the use of an established terminology to refer to the caregiver profile shows the need for constant revision and updating of the terms.

  12. Profile of Scientific Ability of Chemistry Education Students in Basic Physics Course

    Science.gov (United States)

    Suastika, K. G.; Sudyana, I. N.; Lasiani, L.; Pebriyanto, Y.; Kurniawati, N.

    2017-09-01

    The weakness of scientific ability of students in college has been being a concern in this case, especially in terms of laboratory activities to support Laboratory Based Education. Scientific ability is a basic ability that must be dominated by students in basic physics lecturing process as a part of scientific method. This research aims to explore the indicators emergence of the scientific ability of students in Chemistry Education of Study Program, Faculty of Teaching and Education University of Palangka Raya through Inquiry Based Learning in basic physics courses. This research is a quantitative research by using descriptive method (descriptive-quantitative). Students are divided into three categories of group those are excellent group, low group, and heterogeneous group. The result shows that the excellent group and low group have same case that were occured decreasing in the percentage of achievement of scientific ability, while in heterogeneous group was increased. The differentiation of these results are caused by enthusiastic level of students in every group that can be seen in tables of scientific ability achievement aspects. By the results of this research, hoping in the future can be a references for further research about innovative learning strategies and models that can improve scientific ability and scientific reasoning especially for science teacher candidates.

  13. Scientific wealth and inequality within nations

    OpenAIRE

    Prathap, Gangan

    2017-01-01

    We show that the greater the scientific wealth of a nation, the more likely that it will tend to concentrate this excellence in a few premier institutions. That is, great wealth implies great inequality of distribution. The scientific wealth is interpreted in terms of citation data harvested by Google Scholar Citations for profiled institutions from all countries in the world.

  14. Characterization of the psychological, physiological and EEG profile of acute betel quid intoxication in naïve subjects.

    Directory of Open Access Journals (Sweden)

    Peter G Osborne

    Full Text Available Betel quid use and abuse is wide spread in Asia but the physiological basis of intoxication and addiction are unknown. In subjects naïve to the habit of betel quid intoxication, the psychological and physiological profile of intoxication has never been reported. We compared the effect of chewing gum or chewing betel quid, and subsequent betel quid intoxication, on psychological assessment, prospective time interval estimation, numerical and character digit span, computerized 2 choice tests and mental tasks such as reading and mathematics with concurrent monitoring of ECG, EEG and face temperature in healthy, non-sleep deprived, male subjects naïve to the habit of chewing betel quid. Betel quid intoxication, dose dependently induced tachycardia (max 30 bpm and elevated face temperature (0.7°C (P<0.001 above the effects observed in response to chewing gum (max 12 bpm and 0.3°C in 12 subjects. Gross behavioral indices of working memory such as numerical or character digit span in 8 subjects, or simple visual-motor performance such as reaction speed or accuracy in a two choice scenario in 8 subjects were not affected by betel quid intoxication. Betel quid intoxication strongly influenced the psychological aspects of perception such as slowing of the prospective perception of passage of a 1 minute time interval in 8 subjects (P<0.05 and perceived increased arousal (P<0.01 and perceived decreased ability to think (P<0.05 in 31 subjects. The EEG spectral profile recorded from mental states associated with open and closed eyes, and mental tasks such as reading and eyes closed mental arithmetic were significantly modified (P<0.05 relative to chewing gum by betel quid intoxication in 10 subjects. The prevalence of betel quid consumption across a range of social and work settings warrants greater investigation of this widespread but largely under researched drug.

  15. Relationship between cardiometabolic profile, vitamin D status and BsmI polymorphism of the VDR gene in non-institutionalized elderly subjects: Cardiometabolic profile, vitamin D status and BsmI polymorphism of the VDR gene in non-institutionalized elderly subjects.

    Science.gov (United States)

    Issa, Chahira Taha Mahd Ibrahim; Silva, Alexandre Sérgio; Toscano, Luciana Tavares; Medeiros, Marcia Silva; Persuhn, Darlene Camati; da Silva Diniz, Alcides; de Carvalho Costa, Maria José; Rodrigues Gonçalves, Maria da Conceição

    2016-08-01

    This study aimed to evaluate the relationship between the cardiometabolic profile, vitamin D status and BsmI polymorphism of the VDR gene in non-institutionalized elderly subjects. A cross-sectional study was conducted with a random and representative sample of 142 elderly subjects selected by cluster and recruited from a municipal assistance program. Clinical, nutritional, biochemical and inflammatory profiles, oxidative stress and genotyping for the BsmI polymorphism were evaluated. Participants had mean age of 69.9 (7.0) years, BMI of 28.3 (4.4) kg/m(2) and 80.3% were women. The prevalence of a 25-hydroxyvitamin D [25(OH)D] status vitamin D levelDD≥75nmol/L]; this relationship was maintained only for women in the analysis by sex. The BsmI polymorphism showed allelic frequencies in the SUF group of B 49% and b 51% and in the INSUF/DEF group B 38% and b 62%. The frequency of bb homozygosity was significantly associated with lower serum total cholesterol and LDL cholesterol concentrations compared to Bb, both in the general population and in the SUF group. Among individuals with bb, the INSUF/DEF group showed higher levels of triglycerides and VLDL cholesterol. Blood glucose levels and oxidative stress were increased in elderly subjects with 25(OH)Dvitamin D status resulted in lower total and LDL cholesterol, but the benefit was lost when vitamin D insufficiency or deficiency was present. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Influence of sarcopenia and functionality indicators on the frailty profile of community-dwelling elderly subjects: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Joana U. Viana

    2013-08-01

    Full Text Available BACKGROUND: Frailty and sarcopenia are frequent conditions in the elderly and are related to inactivity and functionality. However, little is known about the influence of the sarcopenia indicators on the frailty profile or their functional implications. OBJECTIVE: To evaluate whether the indirect indicators of sarcopenia and functionality influence the frailty profile in elderly subjects. METHOD : This was a cross-sectional study with 53 elderly subjects recruited by an active search in a secondary health care service. The indirect indicators of sarcopenia were body mass index (BMI, gait speed, Mini-Nutritional Assessment (MNA, Human Activity Profile (HAP, and handgrip strength. Frailty was characterized according to Fried's Frailty Phenotype. Functional capacity was assessed according to the Short Physical Performance Battery (SPPB. Physical activity level was assessed by HAP. Data were analyzed by analysis of variance (ANOVA and multiple regression. RESULTS: Overall, 75.5% of the subjects were women, with a mean age of 76.72 (±5.89 years; 15.1% were frail and 54.7% pre-frail; and the level of physical activity was the most prevalent indicator of sarcopenia. Significant differences (p<0.05 were observed in both the physical activity level and gait speed between the non-frail and pre-frail groups and between the non-frail and frail groups. In addition, some sarcopenia indicators were associated with functional capacity and geriatric depression score. CONCLUSION: The level of physical activity and gait speed appeared to be the most relevant factors in the development of frailty in the study sample, which may have functional implications.

  17. Advanced Russian Mission Laplace-P to Study the Planetary System of Jupiter: Scientific Goals, Objectives, Special Features and Mission Profile

    Science.gov (United States)

    Martynov, M. B.; Merkulov, P. V.; Lomakin, I. V.; Vyatlev, P. A.; Simonov, A. V.; Leun, E. V.; Barabanov, A. A.; Nasyrov, A. F.

    2017-12-01

    The advanced Russian project Laplace-P is aimed at developing and launching two scientific spacecraft (SC)— Laplace-P1 ( LP1 SC) and Laplace-P2 ( LP2 SC)—designed for remote and in-situ studies of the system of Jupiter and its moon Ganymede. The LP1 and LP2 spacecraft carry an orbiter and a lander onboard, respectively. One of the orbiter's objectives is to map the surface of Ganymede from the artificial satellite's orbit and to acquire the data for the landing site selection. The main objective of the lander is to carry out in-situ investigations of Ganymede's surface. The paper describes the scientific goals and objectives of the mission, its special features, and the LP1 and LP2 mission profiles during all of the phases—from the launch to the landing on the surface of Ganymede.

  18. Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects

    DEFF Research Database (Denmark)

    Rasmussen, M H; Hvidberg, A; Juul, A

    1995-01-01

    levels of insulin-like growth factor-I (IGF-I), IGF-binding protein-3 (IGFBP-3), as well as insulin in obese subjects before and after a massive weight loss. We studied 18 obese subjects (age, 26 +/- 1 yr; body mass index, 40.9 +/- 1.1 kg/m2); 18 normal age-, and sex-matched control subjects; and 9...... using anthropometric measurements and dual energy x-ray absorptiometry scanning (DXA). In the obese subjects, 24-h spontaneous GH release profiles and the GH responses to insulin-induced hypoglycemia and L-arginine as well as basal IGF-I levels and the IGF-I/IGFBP-3 molar ratio were decreased, whereas...

  19. What is healthy food? Objective nutrient profile scores and subjective lay evaluations in comparison.

    Science.gov (United States)

    Bucher, T; Müller, B; Siegrist, M

    2015-12-01

    To date, it is unclear how consumers evaluate the healthiness of individual foods and meals and how consumers' perceptions are related to expert opinions. This knowledge is essential for efficient communication of nutrition information with the goal of promoting healthy eating. This study used the fake food buffet method to investigate health perceptions of selected meals and of 54 individual foods and beverages. Lay consumers' subjective healthiness evaluations of meals and foods were compared to objective nutrient profile scores, which were previously shown to correlate highly with expert opinions. The results show that nutrition profile scores and lay evaluations were highly correlated, which indicates that lay people used similar criteria as experts to evaluate the healthiness of foods. However, lay consumers tended to neglect the amount of saturated fat, protein and sodium for their judgments. Also, it was found that while lay consumers were quite able to evaluate single food products, they had difficulties in evaluating entire meals. Future interventions should focus particularly on educating the consumer about the negative effects of diets high in salt and saturated fat and they should improve the consumer's abilities to evaluate entire meals. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. New biomarkers of coffee consumption identified by the non-targeted metabolomic profiling of cohort study subjects.

    Directory of Open Access Journals (Sweden)

    Joseph A Rothwell

    Full Text Available Coffee contains various bioactives implicated with human health and disease risk. To accurately assess the effects of overall consumption upon health and disease, individual intake must be measured in large epidemiological studies. Metabolomics has emerged as a powerful approach to discover biomarkers of intake for a large range of foods. Here we report the profiling of the urinary metabolome of cohort study subjects to search for new biomarkers of coffee intake. Using repeated 24-hour dietary records and a food frequency questionnaire, 20 high coffee consumers (183-540 mL/d and 19 low consumers were selected from the French SU.VI.MAX2 cohort. Morning spot urine samples from each subject were profiled by high-resolution mass spectrometry. Partial least-square discriminant analysis of multidimensional liquid chromatography-mass spectrometry data clearly distinguished high consumers from low via 132 significant (p-value<0.05 discriminating features. Ion clusters whose intensities were most elevated in the high consumers were annotated using online and in-house databases and their identities checked using commercial standards and MS-MS fragmentation. The best discriminants, and thus potential markers of coffee consumption, were the glucuronide of the diterpenoid atractyligenin, the diketopiperazine cyclo(isoleucyl-prolyl, and the alkaloid trigonelline. Some caffeine metabolites, such as 1-methylxanthine, were also among the discriminants, however caffeine may be consumed from other sources and its metabolism is subject to inter-individual variation. Receiver operating characteristics curve analysis showed that the biomarkers identified could be used effectively in combination for increased sensitivity and specificity. Once validated in other cohorts or intervention studies, these specific single or combined biomarkers will become a valuable alternative to assessment of coffee intake by dietary survey and finally lead to a better understanding of

  1. The effect of sauna bathing on lipid profile in young, physically active, male subjects.

    Science.gov (United States)

    Gryka, Dorota; Pilch, Wanda; Szarek, Marta; Szygula, Zbigniew; Tota, Łukasz

    2014-08-01

    The aim of the study was to evaluate effects of Finnish sauna bathing on lipid profile in healthy, young men. Sixteen male subjects (20-23 years) were subjected to 10 sauna bathing sessions in a Finnish sauna every 1 or 2 days. The mean sauna temperature was 90±2°C, while humidity was 5-16%. Each session consisted of three 15-minute parts and a 2-minute cool-down between them. The following measurements were taken before and after the sauna sessions: body mass, heart rate, body skinfold thickness. The percentage fat content and then, the lean body mass were calculated. Total cholesterol, triacylglycerols, lipoprotein cholesterol LDL and HDL were measured in blood samples. A statistically significant decrease of total cholesterol and LDL cholesterol was observed during 3 weeks of sauna treatment and in the week afterwards. A significant decline in triacylglycerols was found directly after the 1st and 24 h directly after the 10th sauna session. After the 10th sauna session the level of HDL cholesterol remained slightly increased, but this change was not statistically significant. A decrease in blood plasma volume was found directly after the 1st and the last sauna bathing session due to perspiration. An adaptive increase in blood plasma volume was also found after the series of 10 sauna sessions. Ten complete sauna bathing sessions in a Finnish sauna caused a reduction in total cholesterol and LDL cholesterol fraction levels during the sessions and a gradual return of these levels to the initial level during the 1st and the 2nd week after the experiment. A small, statistically insignificant increase in HDL-C level and a transient decline in triacylglycerols were observed after those sauna sessions. The positive effect of sauna on lipid profile is similar to the effect that can be obtained through a moderate-intensity physical exercise.

  2. [The theme of disaster in health care: profile of technical and scientific production in the specialized database on disasters of the Virtual Health Library - VHL].

    Science.gov (United States)

    Rocha, Vania; Ximenes, Elisa Francioli; Carvalho, Mauren Lopes de; Alpino, Tais de Moura Ariza; Freitas, Carlos Machado de

    2014-09-01

    In the specialized database of the Virtual Health Library (VHL), the DISASTER database highlights the importance of the theme for the health sector. The scope of this article is to identify the profiles of technical and scientific publications in the specialized database. Based on systematic searches and the analysis of results it is possible to determine: the type of publication; the main topics addressed; the most common type of disasters mentioned in published materials, countries and regions as subjects, historic periods with the most publications and the current trend of publications. When examining the specialized data in detail, it soon becomes clear that the number of major topics is very high, making a specific search process in this database a challenging exercise. On the other hand, it is encouraging that the disaster topic is discussed and assessed in a broad and diversified manner, associated with different aspects of the natural and social sciences. The disaster issue requires the production of interdisciplinary knowledge development to reduce the impacts of disasters and for risk management. In this way, since the health sector is a interdisciplinary area, it can contribute to knowledge production.

  3. Visualization in scientific computing

    National Research Council Canada - National Science Library

    Nielson, Gregory M; Shriver, Bruce D; Rosenblum, Lawrence J

    1990-01-01

    The purpose of this text is to provide a reference source to scientists, engineers, and students who are new to scientific visualization or who are interested in expanding their knowledge in this subject...

  4. [M.S. Gilyarov's Scientific School of Soil Zoology].

    Science.gov (United States)

    Chesnova, L V

    2005-01-01

    The role of M.S. Gilyarov's scientific school in the development of the subject and methodology of a new complex discipline formed in the mid-20th century--soil zoology--was considered. The establishment and evolution of the proper scientific school was periodized. The creative continuity and development of the basic laws and technical approaches included in the teacher's scientific program was demonstrated by scientific historical analysis.

  5. Talinum triangulare Whole wheat meal fortified with soy flour consumed with Talinum triangulare (gbure) soup glycemic index and the test human subjects' lipid profiles.

    Science.gov (United States)

    Emaleku, Sunday Adeola; Omueti, Olusola D; Emaleku, Godsent Oluwakemi

    2017-08-24

    Cardiovascular diseases (CVDs) and diabetes mellitus (DM) are some of the leading causes of death in the world, and diet has roles in their etiology. This research study therefore investigates the glycemic index (GI) of soy flour fortified whole wheat meal (SFFWWM) consumed with Talinum triangulare (gbure) soup and the effects of the meal on the lipid profiles of the test human subjects. The control human subjects and test human subjects were fed D-glucose (DG) and whole wheat meal (WWM) with Talinum triangulare soup respectively on the first day of the experiment, and SFFWWM with the same soup the next day (for test subjects only) after 10-12h overnight fasting. Blood glucose levels of the subjects were taken before and 2h after meals' consumption at 30min interval and blood samples collected for lipid profiles evaluations. The result of the study showed that; SFFWWM consumed with Talinum trianguilare soup has a non-significant lower GI than WWM consumed with the same soup, but a significant lower GI than DG at (P<0.05). Furthermore, there was no significant difference in lipid profiles of the test human subjects between when they consumed WWM and SFFWWM with the soup however, SFFWWM reduced TC, TG, LDL-C and VDL-C and increased HDL-C and TP than WMM at (P<0.05). In addition, GI is positively correlated with TC, TG, LDL-C and VLDL-C, but is negatively correlated with TP and HDL-C. It can therefore be concluded that; fortifying WWM with soy flour would reduce the risk factors of CVDs and DM, the diseases recently claiming thousands of today. Copyright © 2017 Diabetes India. Published by Elsevier Ltd. All rights reserved.

  6. The ecology of hydric hammocks: a community profile

    Science.gov (United States)

    Vince, Susan W.; Humphrey, Stephen R.; Simons, Robert W.

    1989-01-01

    This community profile is one in a series of Fish and Wildlife Service publications compiled to provide a state-of-knowledge synthesis of scientific information and literature on various coastal habitats. The subject of this profile is the hydric hammock, a distinctive type of forested wetland occurring at low elevations along the gulf coast of Florida from Aripeka to St. Marks and at various inland sites in Florida. Relatively little research has been conducted in hydric hammocks, and no thorough effort has been made previously to define this community. Consequently, no consensus has existed about the extent and nature of this community; some published works and active researchers have differed in their judgments about it; and the entity sometimes is ignored and often is lumped with other types of mixed hardwood forests. The purpose of this profile is to establish or clarify an identification and understanding of the hydric-hammock community. Information for the profile was gathered from published and unpublished literature, from persona 1 communication with many technical experts, and from our own fie 1 d experience. The profile includes some new data gathered in the field for the purpose of defining this community. It is hoped that the content and format of the profile will be useful to a broad spectrum of users, including other scientists, students, resource managers and planners, teachers, and interested citizens. The profile includes structural and functional aspects of the community: its physical setting, plant and animal composition and dynamics, interactions of its flora and fauna, and its relationships with other communities.

  7. The Influence of CYP2D6 Phenotype on the Pharmacokinetic Profile of Atomoxetine in Caucasian Healthy Subjects

    Directory of Open Access Journals (Sweden)

    Todor Ioana

    2017-06-01

    Full Text Available Objective: To analyze a potential phenotypic variation within the studied group based on the pharmacokinetic profile of atomoxetine and its active metabolite, and to further investigate the impact of CYP2D6 phenotype on atomoxetine pharmacokinetics. Methods: The study was conducted as an open-label, non-randomized clinical trial which included 43 Caucasian healthy volunteers. Each subject received a single oral dose of atomoxetine 25 mg. Subsequently, atomoxetine and 4-hydroxyatomoxetine-O-glucuronide (glucuronidated active metabolite plasma concentrations were determined and a noncompartmental method was used to calculate the pharmacokinetic parameters of both compounds. Further on, the CYP2D6 metabolic phenotype was assessed using the area under the curve (AUC metabolic ratio (atomoxetine/ 4-hydroxyatomoxetine-O-glucuronide and specific statistical tests (Lilliefors (Kolgomorov-Smirnov and Anderson-Darling test. The phenotypic differences in atomoxetine disposition were identified based on the pharmacokinetic profile of the parent drug and its metabolite. Results: The statistical analysis revealed that the AUC metabolic ratio data set did not follow a normal distribution. As a result, two different phenotypes were identified, respectively the poor metabolizer (PM group which included 3 individuals and the extensive metabolizer (EM group which comprised the remaining 40 subjects. Also, it was demonstrated that the metabolic phenotype significantly influenced atomoxetine pharmacokinetics, as PMs presented a 4.5-fold higher exposure to the parent drug and a 3.2-fold lower exposure to its metabolite in comparison to EMs. Conclusions: The pharmacokinetic and statistical analysis emphasized the existence of 2 metabolic phenotypes: EMs and PMs. Furthermore, it was proved that the interphenotype variability had a marked influence on atomoxetine pharmacokinetic profile.

  8. Elevated 1-hour postload plasma glucose levels identify subjects with normal glucose tolerance but impaired β-cell function, insulin resistance, and worse cardiovascular risk profile: the GENFIEV study.

    Science.gov (United States)

    Bianchi, Cristina; Miccoli, Roberto; Trombetta, Maddalena; Giorgino, Francesco; Frontoni, Simona; Faloia, Emanuela; Marchesini, Giulio; Dolci, Maria A; Cavalot, Franco; Cavallo, Gisella; Leonetti, Frida; Bonadonna, Riccardo C; Del Prato, Stefano

    2013-05-01

    In subjects with normal glucose tolerance (NGT) 1-hour postload plasma glucose (1-h oral glucose tolerance test [OGTT]) of >155 mg/dL predicts type 2 diabetes (T2DM) and is associated with subclinical atherosclerosis. The purpose of this study was to evaluate β-cell function, insulin resistance, and cardiovascular risk profile in subjects with NGT with a 1-h OGTT glucose of >155 mg/dL. The GENFIEV (Genetics, PHYsiopathology, and Evolution of Type 2 diabetes) study is a multicenter study recruiting individuals at high risk of T2DM. A total of 926 subjects underwent a 75-g OGTT for assessment of plasma glucose and C-peptide for mathematical modeling of β-cell function (derivative and proportional control). Fasting insulin, lipid profile, and clinical parameters were determined as well. A 1-hour OGTT glucose of >155 mg/dL was found in 39% of subjects with NGT, 76% with impaired fasting glucose (IFG), 90% with impaired glucose tolerance (IGT), and 99% and 98% with IFG + IGT or newly diagnosed T2DM, respectively. Among subjects with NGT (n = 474), those with 1-hour OGTT glucose of >155 mg/dL were more insulin-resistant and had worse β-cell function than those with 1-hour OGTT glucose of ≤155 mg/dL. Moreover, glycosylated hemoglobin, blood pressure, low-density lipoprotein cholesterol, and triglycerides were higher in subjects with NGT with 1-hour OGTT glucose of >155 mg/dL, whereas high-density lipoprotein cholesterol was lower compared with that in subjects with NGT with 1-hour OGTT glucose of ≤155 mg/dL. Compared with subjects with IGT, those with NGT with 1-hour OGTT glucose of >155 mg/dL had comparable cardiovascular risk profile and insulin resistance but slightly better β-cell function. Among subjects with NGT, those with 1-hour OGTT glucose of >155 mg/dL showed lower insulin sensitivity, impaired β-cell function, and worse cardiovascular risk profile and therefore are at greater risk of developing T2DM and cardiovascular disease.

  9. Investigation on the Inclusion of Socio-Scientific Acquisitions in Curriculum of Science and Technology Lesson

    Science.gov (United States)

    Guler, Mutlu Pinar Demirci

    2013-01-01

    According to its definition, socio-scientific subjects emerge during scientific and technologic developments. Besides information, attitude and value constraints are effective in decision-making processes and thus there is no consensus on socio-scientific subjects yet and it leads to social discussions. These subjects comprise decision making…

  10. A review of Brazilian scientific output on crack - contributions to the political agenda

    Directory of Open Access Journals (Sweden)

    Marcelo Rasga Moreira

    2015-04-01

    Full Text Available Object: scientific literature about crack abuse published in Brazilian journals indexed in SCIELO.Objective: systematic review of literature treating findings as a framework for agenda-setting orienting policy decision makers.Methodology: SCIELO online journals research since 02/06/2013 on tag crack as "key word searched" and in indexes as "research amplitude". An amount of 199 references were identified and their abstracts were analyzed getting to a final group of 59 articles specifically studying crack issues in Brazil. Analysis: institutional criteria (journal, subject area, and publishing time and analytical categories created by the authors: "Social Risk", "Treatment", "Use/Abuse", "Profile", "Social Relations", and "Study".Results: crack use impact Brazilian journals since 2011; health field is prominent; articles about "Associated Risk" and "Treatment" prevail; SUS cannot face demand;investment improvement in CAP and harm reduction; therapeutic communities need to match with SUS standards; youngers, black people and poor express users profile; rave style use; repressive policies were not well succeeded; and multidisciplinary approach are necessary.

  11. A review of Brazilian scientific output on crack--contributions to the political agenda.

    Science.gov (United States)

    Moreira, Marcelo Rasga; Fernandes, Fernando Manuel Bessa; Ribeiro, José Mendes; Franco Neto, Thereza de Lamare

    2015-04-01

    scientific literature about crack abuse published in Brazilian journals indexed in SCIELO. systematic review of literature treating findings as a framework for agenda-setting orienting policy decision makers. SCIELO online journals research since 02/06/2013 on tag crack as "key word searched" and in indexes as "research amplitude". An amount of 199 references were identified and their abstracts were analyzed getting to a final group of 59 articles specifically studying crack issues in Brazil. institutional criteria (journal, subject area, and publishing time) and analytical categories created by the authors: "Social Risk", "Treatment", "Use/Abuse", "Profile", "Social Relations", and "Study". crack use impact Brazilian journals since 2011; health field is prominent; articles about "Associated Risk" and "Treatment" prevail; SUS cannot face demand;investment improvement in CAP and harm reduction; therapeutic communities need to match with SUS standards; youngers, black people and poor express users profile; rave style use; repressive policies were not well succeeded; and multidisciplinary approach are necessary.

  12. Scientific Revolutions and Political Attitudes

    Czech Academy of Sciences Publication Activity Database

    Mervart, Jan

    2014-01-01

    Roč. 2, č. 2 (2014), s. 185-190 ISSN 2336-3142 Institutional support: RVO:67985955 Keywords : Scientific revolution * party historiography * Czechoslovakia * communist reformism Subject RIV: AB - History

  13. Use of scientific social networking to improve the research strategies of PubMed readers.

    Science.gov (United States)

    Evdokimov, Pavel; Kudryavtsev, Alexey; Ilgisonis, Ekaterina; Ponomarenko, Elena; Lisitsa, Andrey

    2016-02-18

    Keeping up with journal articles on a daily basis is an important activity of scientists engaged in biomedical research. Usually, journal articles and papers in the field of biomedicine are accessed through the Medline/PubMed electronic library. In the process of navigating PubMed, researchers unknowingly generate user-specific reading profiles that can be shared within a social networking environment. This paper examines the structure of the social networking environment generated by PubMed users. A web browser plugin was developed to map [in Medical Subject Headings (MeSH) terms] the reading patterns of individual PubMed users. We developed a scientific social network based on the personal research profiles of readers of biomedical articles. A browser plugin is used to record the digital object identifier or PubMed ID of web pages. Recorded items are posted on the activity feed and automatically mapped to PubMed abstract. Within the activity feed a user can trace back previously browsed articles and insert comments. By calculating the frequency with which specific MeSH occur, the research interests of PubMed users can be visually represented with a tag cloud. Finally, research profiles can be searched for matches between network users. A social networking environment was created using MeSH terms to map articles accessed through the Medline/PubMed online library system. In-network social communication is supported by the recommendation of articles and by matching users with similar scientific interests. The system is available at http://bioknol.org/en/.

  14. The effect of sauna bathing on lipid profile in young, physically active, male subjects

    Directory of Open Access Journals (Sweden)

    Dorota Gryka

    2014-08-01

    Full Text Available Objectives: The aim of the study was to evaluate effects of Finnish sauna bathing on lipid profile in healthy, young men. Material and Methods: Sixteen male subjects (20–23 years were subjected to 10 sauna bathing sessions in a Finnish sauna every 1 or 2 days. The mean sauna temperature was 90±2°C, while humidity was 5–16%. Each session consisted of three 15-minute parts and a 2-minute cool-down between them. The following measurements were taken before and after the sauna sessions: body mass, heart rate, body skinfold thickness. The percentage fat content and then, the lean body mass were calculated. Total cholesterol, triacylglycerols, lipoprotein cholesterol LDL and HDL were measured in blood samples. Results: A statistically significant decrease of total cholesterol and LDL cholesterol was observed during 3 weeks of sauna treatment and in the week afterwards. A significant decline in triacylglycerols was found directly after the 1st and 24 h directly after the 10th sauna session. After the 10th sauna session the level of HDL cholesterol remained slightly increased, but this change was not statistically significant. A decrease in blood plasma volume was found directly after the 1st and the last sauna bathing session due to perspiration. An adaptive increase in blood plasma volume was also found after the series of 10 sauna sessions. Conclusions: Ten complete sauna bathing sessions in a Finnish sauna caused a reduction in total cholesterol and LDL cholesterol fraction levels during the sessions and a gradual return of these levels to the initial level during the 1st and the 2nd week after the experiment. A small, statistically insignificant increase in HDL-C level and a transient decline in triacylglycerols were observed after those sauna sessions. The positive effect of sauna on lipid profile is similar to the effect that can be obtained through a moderate-intensity physical exercise.

  15. [An approach to a methodology of scientific research for assistant-students].

    Science.gov (United States)

    Novak, Ivón T C; Bejarano, Paola Antón; Rodríguez, Fernando Marcos

    2007-01-01

    This work is presented from a "problematic" perspective in the attempt to establish a dialogic relationship between the educator and the student-subject, mediated by the object of knowledge. It is oriented to the integral education of the helping students departing from a closer approach to the scientific research. This work was carried out by a teacher and two hired students. This project was developed in relation with the profile required for the career of medicine in the Faculty of Medicine of the National University of Cordoba which--among other aspects- addresses the importance of "adopting a positive attitude towards research based on knowledge and the application of the scientific methodology" and towards "the development of a responsible self-learning and continuous improvements" (sic). Thus, this work tries to be aligned with this perspectives. I. Characterization of the scientific methodology. Search for bibliography and discussion of scientific works. II. Optimization of the methodology for the observation of leucocytes: blood samples donated by healthy people, non-coagulating with citrate or with EDTA (Blood reservoir of the UNC (National University of Cordoba) n = 20. a) Blood smear of full blood. b) centrifugation at 200g of plasma and aspirated leucocytes after erythro sedimentation and re suspension of the cell pellet and cyto-dispersion. Cytological and cyto-chemical techniques. I. Deeper knowledge about blood field was achieved. It generated an appropriate atmosphere to produce scientific questioning and the activities involved in the process were carried out responsibly. II. Better results were achieved using EDTA for the observation and analysis of leucocytes. It was possible to attain the objectives for an approach to a scientific research as well as for a contribution towards a responsible development in the continuous learning process.

  16. Towards Scientific Literacy for Basic School Pupils: Which Profile ...

    African Journals Online (AJOL)

    cce

    2005-06-30

    Jun 30, 2005 ... The emphasis on providing science education for all students in an attempt to make citizens .... the most important profile dimension in teaching, learning and ... The goal is to promote the acquisition of higher-order thinking ...

  17. Scientific and Technological Report 2011

    International Nuclear Information System (INIS)

    Lopez Milla, Alcides; Prado Cuba, Antonio; Agapito Panta, Juan; Montoya Rossi, Eduardo

    2013-01-01

    This annual scientific and technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2011. This report includes 30 papers divided in 8 subject matters, such as: physics and chemistry, materials science, nuclear engineering, mining industrial and environmental applications, medical and biological applications, radiation protection and nuclear safety, scientific instrumentation and management aspects. It also includes annexes. (APC)

  18. Scientific and Technological Report 2010

    International Nuclear Information System (INIS)

    Prado Cuba, Antonio; Santiago Contreras, Julio; Solis Veliz, Jose; Lopez Moreno, Edith

    2011-10-01

    This annual scientific and technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2010. This report includes 41 papers divided in 8 subject matters, such as: physics and chemistry, materials science, nuclear engineering, mining industrial and environmental applications, medical and biological applications, radiation protection and nuclear safety, scientific instrumentation and management aspects. It also includes annexes. (APC)

  19. Systems Engineering and Safety Issues in Scientific Facilities Subject to Ionizing Radiations

    Directory of Open Access Journals (Sweden)

    Pierre Bonnal

    2013-10-01

    Full Text Available The conception and development of large-scale scientific facilities emitting ionizing radiations rely more on project management practices in use in the process industry than on systems engineering practices. This paper aims to highlight possible reasons for this present situation and to propose some ways to enhance systems engineering so that the specific radiation safety requirements are considered and integrated in the approach. To do so, we have reviewed lessons learned from the management of large-scale scientific projects and more specifically that of the Large Hadron Collider project at CERN. It is shown that project management and systems engineering practices are complementary and can beneficially be assembled in an integrated and lean managerial framework that grants the appropriate amount of focus to safety and radiation safety aspects.

  20. Characterization of the psychological, physiological and EEG profile of acute betel quid intoxication in naïve subjects.

    Science.gov (United States)

    Osborne, Peter G; Chou, Tung-Shan; Shen, Tsu-Wang

    2011-01-01

    Betel quid use and abuse is wide spread in Asia but the physiological basis of intoxication and addiction are unknown. In subjects naïve to the habit of betel quid intoxication, the psychological and physiological profile of intoxication has never been reported. We compared the effect of chewing gum or chewing betel quid, and subsequent betel quid intoxication, on psychological assessment, prospective time interval estimation, numerical and character digit span, computerized 2 choice tests and mental tasks such as reading and mathematics with concurrent monitoring of ECG, EEG and face temperature in healthy, non-sleep deprived, male subjects naïve to the habit of chewing betel quid. Betel quid intoxication, dose dependently induced tachycardia (max 30 bpm) and elevated face temperature (0.7°C) (Pbetel quid intoxication. Betel quid intoxication strongly influenced the psychological aspects of perception such as slowing of the prospective perception of passage of a 1 minute time interval in 8 subjects (Pbetel quid intoxication in 10 subjects. The prevalence of betel quid consumption across a range of social and work settings warrants greater investigation of this widespread but largely under researched drug.

  1. Electronic cigarettes: abuse liability, topography and subjective effects.

    Science.gov (United States)

    Evans, Sarah E; Hoffman, Allison C

    2014-05-01

    To review the available evidence evaluating the abuse liability, topography, subjective effects, craving and withdrawal suppression associated with e-cigarette use in order to identify information gaps and provide recommendations for future research. Literature searches were conducted between October 2012 and January 2014 using five electronic databases. Studies were included in this review if they were peer-reviewed scientific journal articles evaluating clinical laboratory studies, national surveys or content analyses. A total of 15 peer-reviewed articles regarding behavioural use and effects of e-cigarettes published between 2010 and 2014 were included in this review. Abuse liability studies are limited in their generalisability. Topography (consumption behaviour) studies found that, compared with traditional cigarettes, e-cigarette average puff duration was significantly longer, and e-cigarette use required stronger suction. Data on e-cigarette subjective effects (such as anxiety, restlessness, concentration, alertness and satisfaction) and withdrawal suppression are limited and inconsistent. In general, study data should be interpreted with caution, given limitations associated with comparisons of novel and usual products, as well as the possible effects associated with subjects' previous experience/inexperience with e-cigarettes. Currently, very limited information is available on abuse liability, topography and subjective effects of e-cigarettes. Opportunities to examine extended e-cigarette use in a variety of settings with experienced e-cigarette users would help to more fully assess topography as well as behavioural and subjective outcomes. In addition, assessment of 'real-world' use, including amount and timing of use and responses to use, would clarify behavioural profiles and potential adverse health effects.

  2. Single Subject Research: Applications to Special Education

    Science.gov (United States)

    Cakiroglu, Orhan

    2012-01-01

    Single subject research is a scientific research methodology that is increasingly used in the field of special education. Therefore, understanding the unique characteristics of single subject research methodology is critical both for educators and practitioners. Certain characteristics make single subject research one of the most preferred…

  3. The Effects of 6 Isocaloric Meals on Body Weight, Lipid Profiles, Leptin, and Adiponectin in Overweight Subjects (BMI > 25).

    Science.gov (United States)

    Hatami Zargaran, Zeynab; Salehi, Moosa; Heydari, Seyed Taghi; Babajafari, Siavash

    2014-04-01

    It seems that meal frequency is negatively related to body weight, but the relationship between meal frequency and weight loss is not clearly known yet. The present study aimed to investigate whether 6 isocaloric meals affected body weight, lipid profiles, leptin, and adiponectin in overweight subjects. The present randomized controlled trial was conducted on 90 overweight subjects in 3 months. The subjects were randomly divided into two groups. The control group continued their normal diet, while the intervention group was required to follow a 6 isocaloric meal diet instead of their previous meal pattern (3 meals and 2 snacks). The planned reduced calorie diets for both groups were identical, except for meal pattern. Blood samples were analyzed prior to and at the end of the study for total cholesterol, triglyceride, HDL-C, LDL-C, leptin, and adiponectinn concentrations. Paired t-test was used for comparison of the measurements before and after the study in each group. Besides, independent t-test was used for comparison of the measurements between the groups. P value less than 0.05 was considered as statistically significant. The mean age of the participants was 36.38 ± 9.7 in the intervention group and 37.6 ± 10.9 in the control group. In comparison to the control group, the intervention group showed a significant decrease in total cholesterol (P meal pattern led to a reduction in BMI, lipid profiles (total cholesterol, LDL-C, triglyceride), and leptin concentrations and an increase in HDL and adiponectin compared to the normal diet.

  4. Transforming Data: An Ethnography of Scientific Data from the Brazilian Amazon

    DEFF Research Database (Denmark)

    Walford, Antonia Caitlin

    This thesis is an ethnography of scientific data produced by a Brazil-led scientific project in the Brazilian Amazon. It describes how the researchers and technicians make data about the Amazon forest, and how this data in turn generates different scientific communities, scientific subjectivities...

  5. Manual on JSSL (JAERI scientific subroutine library)

    International Nuclear Information System (INIS)

    Fujimura, Toichiro; Nishida, Takahiko; Asai, Kiyoshi

    1977-05-01

    A manual on the revised JAERI scientific subroutine library is presented. The library is a collection of subroutines developed or modified in JAERI which complements the library installed for FACOM 230-75 computer. It is subject to further extension in the future, since the present one is still insufficient for scientific calculations. (auth.)

  6. Serum Amino Acid Profiles in Normal Subjects and in Patients with or at Risk of Alzheimer Dementia.

    Science.gov (United States)

    Corso, Gaetano; Cristofano, Adriana; Sapere, Nadia; la Marca, Giancarlo; Angiolillo, Antonella; Vitale, Michela; Fratangelo, Roberto; Lombardi, Teresa; Porcile, Carola; Intrieri, Mariano; Di Costanzo, Alfonso

    2017-01-01

    Abnormalities in the plasma amino acid profile have been reported in Alzheimer disease (AD), but no data exist for the prodromal phase characterized by subjective memory complaint (SMC). It was our aim to understand if serum amino acid levels change along the continuum from normal to AD, and to identify possible diagnostic biomarkers. Serum levels of 15 amino acids and 2 organic acids were determined in 4 groups of participants - 29 with probable AD, 18 with mild cognitive impairment (MCI), 24 with SMC, and 46 cognitively healthy subjects (HS) - by electrospray tandem mass spectrometry. Glutamate, aspartate, and phenylalanine progressively decreased, while citrulline, argi-ninosuccinate, and homocitrulline progressively increased, from HS over SMC and MCI to AD. The panel including these 6 amino acids and 4 ratios (glutamate/citrulline, citrulline/phenylalanine, leucine plus isoleucine/phenylalanine, and arginine/phenylalanine) discriminated AD from HS with about 96% accuracy. Other panels including 20 biomarkers discriminated SMC or MCI from AD or HS with an accuracy ranging from 88 to 75%. Amino acids contribute to a characteristic metabotype during the progression of AD along the continuum from health to frank dementia, and their monitoring in elderly individuals might help to detect at-risk subjects.

  7. Characterization of the Psychological, Physiological and EEG Profile of Acute Betel Quid Intoxication in Naïve Subjects

    Science.gov (United States)

    Osborne, Peter G.; Chou, Tung-Shan; Shen, Tsu-Wang

    2011-01-01

    Betel quid use and abuse is wide spread in Asia but the physiological basis of intoxication and addiction are unknown. In subjects naïve to the habit of betel quid intoxication, the psychological and physiological profile of intoxication has never been reported. We compared the effect of chewing gum or chewing betel quid, and subsequent betel quid intoxication, on psychological assessment, prospective time interval estimation, numerical and character digit span, computerized 2 choice tests and mental tasks such as reading and mathematics with concurrent monitoring of ECG, EEG and face temperature in healthy, non-sleep deprived, male subjects naïve to the habit of chewing betel quid. Betel quid intoxication, dose dependently induced tachycardia (max 30 bpm) and elevated face temperature (0.7°C) (Pchewing gum (max 12 bpm and 0.3°C) in 12 subjects. Gross behavioral indices of working memory such as numerical or character digit span in 8 subjects, or simple visual-motor performance such as reaction speed or accuracy in a two choice scenario in 8 subjects were not affected by betel quid intoxication. Betel quid intoxication strongly influenced the psychological aspects of perception such as slowing of the prospective perception of passage of a 1 minute time interval in 8 subjects (Pincreased arousal (Pchewing gum by betel quid intoxication in 10 subjects. The prevalence of betel quid consumption across a range of social and work settings warrants greater investigation of this widespread but largely under researched drug. PMID:21909371

  8. Leveraging the fullest potential of scientific collections through digitisation.

    Directory of Open Access Journals (Sweden)

    Roger Charles Baird

    2010-10-01

    Full Text Available Access to digitised specimen data is a vital means to distribute information and in turn create knowledge. Pooling the accessibility of specimen and observation data under common standards and harnessing the power of distributed datasets places more and more information and the disposal of a globally dispersed work force, which would otherwise carry on its work in relative isolation, and with limited profile and impact. Citing a number of higher profile national and international projects, it is argued that a globally coordinated approach to the digitisation of a critical mass of scientific specimens and specimen-related data is highly desirable and required, to maximize the value of these collections to civil society and to support the advancement of our scientific knowledge globally.

  9. The influence of an undergraduate scientific initiation programme on the professional profile of new physicians.

    Science.gov (United States)

    Cyrillo, Raphael Joaquim Teles; Setúbal, Sérgio; da Silva, Cyro Teixeira; Velarde, Luis Guillermo Coca; de Mattos, Ana Carolina Musser Tavares; Cardoso, Renato Bergallo Bezerra; Cardoso, Gilberto Perez

    2010-01-01

    This paper studies the influence of a Scientific Initiation Programme (SIP) on the professional profile of new doctors from a Brazilian university. Evaluate fifty-two new doctors divided into two groups matched by sex, age and academic performance and differing only in participation in the SIP. Professional and socioeconomic data were collected, including schooling of parents; average income before, during and after the medical course; current professional situation; results of exams for civil servant recruitment; and titles and degrees obtained after graduation. Significant differences were found only in civil servant recruitment exam results (p = 0.0098) and in income after graduation (p = 0.02), which were both higher in the non-SIP group. Only one doctor got a M.Sc. degree after graduation, but many of them in both groups obtained technical titles, and had papers presented at congresses or published. Apparently, taking part in a SIP led to lower income and worse civil servant recruitment exam results. However, this may only reflect a transient phase in a long-term process. New research currently under way will answer this remaining question, now that more time has elapsed since graduation.

  10. Manual on JSSL (JAERI scientific subroutine library)

    International Nuclear Information System (INIS)

    Fujimura, Toichiro; Nishida, Takahiko; Asai, Kiyoshi

    1979-11-01

    A manual on the revised version of JAERI scientific subroutine library is presented. The library is a collection of subroutines developed or modified in JAERI. They are classified into fifteen fields. It is subject to further extension in the future, since there are some fields still insufficient for scientific calculations in the present library. (author)

  11. Ethical muscle and scientific interests: a role for philosophy in scientific research.

    Science.gov (United States)

    Kaposy, Chris

    2008-03-01

    Ethics, a branch of philosophy, has a place in the regulatory framework of human subjects research. Sometimes, however, ethical concepts and arguments play a more central role in scientific activity. This can happen, for example, when violations of research norms are also ethical violations. In such a situation, ethical arguments can be marshaled to improve the quality of the scientific research. I explore two different examples in which philosophers and scientists have used ethical arguments to plead for epistemological improvements in the conduct of research. The first example deals with research dishonesty in pharmaceutical development. The second example is concerned with neuropsychological research using fMRI technology.

  12. [Performance analysis of scientific researchers in biomedicine].

    Science.gov (United States)

    Gamba, Gerardo

    2013-01-01

    There is no data about the performance of scientific researchers in biomedicine in our environment that can be use by individual subjects to compare their execution with their pairs. Using the Scopus browser the following data from 115 scientific researchers in biomedicine were obtained: actual institution, number of articles published, place on each article within the author list as first, last or unique author, total number of citations, percentage of citations due to the most cited paper, and h-index. Results were analyzed with descriptive statistics and simple lineal regressions. Most of scientific researches in the sample are from the National Institutes of the Health Ministry or some of the research institutes or faculties at the Universidad Nacional Autónoma de México. Total number of publications was biomedicine in Mexico City, which can be used to compare the productivity of individual subjects with their pairs.

  13. Profile and scientific production of the Brazilian Council for Scientific and Technological Development (CNPq) researchers in the field of Hematology/Oncology.

    Science.gov (United States)

    Oliveira, Maria Christina Lopes Araujo; Martelli, Daniella Reis; Quirino, Isabel Gomes; Colosimo, Enrico Antônio; Silva, Ana Cristina Simões e; Martelli Júnior, Hercílio; Oliveira, Eduardo Araujo de

    2014-01-01

    several studies have examined the academic production of the researchers at the CNPq, in several areas of knowledge. The aim of this study was to evaluate the scientific production of researchers in Hematology/Oncology who hold scientific productivity grants from the Brazilian Council for Scientific and Technological Development. the Academic CVs of 28 researchers in Hematology/Oncology with active grants in the three-year period from 2006 to 2008 were included in the analysis. The variables of interest were: institution, researchers' time after doctorate, tutoring of undergraduate students, masters and PhD degree, scientific production and its impact. from a total of 411 researchers in Medicine, 28 (7%) were identified as being in the area of Hematology/Oncology. There was a slight predominance of males (53.6%) and grant holders in category 1. Three Brazilian states are responsible for approximately 90% of the researchers: São Paulo (21,75%), Rio de Janeiro (3,11%), and Minas Gerais (2, 7%). During their academic careers, the researchers published 2,655 articles, with a median of 87 articles per researcher (IQR = 52 to 122). 65 and 78% of this total were indexed on the Web of Science and Scopus databases, respectively. The researchers received 14,247 citations on the WoS database with a median of 385 citations per researcher. The average number of citations per article was 8.2. in this investigation, it was noted that researchers in the field of Hematology/Oncology have a relevant scientific output from the point of view of quantity and quality compared to other medical specialties.

  14. Rape in Armed Conflicts in the Democratic Republic of Congo: A Systematic Review of the Scientific Literature.

    Science.gov (United States)

    Kabengele Mpinga, Emmanuel; Koya, Mapendo; Hasselgard-Rowe, Jennifer; Jeannot, Emilien; Rehani, Sylvie B; Chastonay, Philippe

    2017-12-01

    We conducted a systematic review of the scientific literature between 1996 and 2013 on rape in war-ridden Eastern Democratic Republic of Congo (DRC) in order to better understand the interest of the scientific community in describing the magnitude and characteristics of the problem. The literature search was conducted in French and English using several databases (Pubmed, PsycInfo, Sapphire, BDSP, Embase, Rero, and Web of Science) with the key words "rape and DRC" combined with several Medical Subject Headings concepts. Our systematic review yielded 2,087 references, among which only 27 are original studies, that is 20 are based on population surveys and the remaining 7 are original data based on case studies and reviews. Ten studies provided prevalence rates of rape victims, 18 provided specific information on the profile of the victims, 10 reported that most of the perpetrators of rape were military personnel, 14 referred to the negligence of the government in protecting victims, and 10 reported a lack of competent health-care facilities. The awareness of rape in conflict-ridden DRC is still limited as reported in the scientific literature: Published scientific papers are scarce. Yet more research would probably help mobilize local authorities and the international community against this basic human rights violation.

  15. Comparative Difficulties with Non-Scientific General Vocabulary and Scientific/Medical Terminology in English as a Second Language (ESL) Medical Students.

    Science.gov (United States)

    Heming, Thomas A; Nandagopal, Shobha

    2012-11-01

    Medical education requires student comprehension of both technical (scientific/medical) and non-technical (general) vocabulary. Our experience with "English as a second language" (ESL) Arab students suggested they often have problems comprehending scientific statements because of weaknesses in their understanding of non-scientific vocabulary. This study aimed to determine whether ESL students have difficulties with general vocabulary that could hinder their understanding of scientific/medical texts. A survey containing English text was given to ESL students in the premedical years of an English-medium medical school in an Arabic country. The survey consisted of sample questions from the Medical College Admission Test (USA). Students were instructed to identify all unknown words in the text. ESL students commenced premedical studies with substantial deficiencies in English vocabulary. Students from English-medium secondary schools had a selective deficiency in scientific/medical terminology which disappeared with time. Students from Arabic-medium secondary schools had equal difficulty with general and scientific/medical vocabulary. Deficiencies in both areas diminished with time but remained even after three years of English-medium higher education. Typically, when teaching technical subjects to ESL students, attention is focused on subject-unique vocabulary and associated modifiers. This study highlights that ESL students also face difficulties with the general vocabulary used to construct statements employing technical words. Such students would benefit from increases in general vocabulary knowledge.

  16. Constructed vs. received graphical representations for learning about scientific controversy: Implications for learning and coaching

    Science.gov (United States)

    Cavalli-Sforza, Violetta Laura Maria

    Students in science classes hardly ever study scientific controversy, especially in terms of the different types of arguments used to support and criticize theories and hypotheses. Yet, learning the reasons for scientific debate and scientific change is an important part of appreciating the nature of the scientific enterprise and communicating it to the non-scientific world. This dissertation explores the usefulness of graphical representations in teaching students about scientific arguments. Subjects participating in an extended experiment studied instructional materials and used the Belvedere graphical interface to analyze texts drawn from an actual scientific debate. In one experimental condition, subjects used a box-and-arrow representation whose primitive graphical elements had preassigned meanings tailored to the domain of instruction. In the other experimental condition, subjects could use the graphical elements as they wished, thereby creating their own representation. The development of a representation, by forcing a deeper analysis, can potentially yield a greater understanding of the domain under study. The results of the research suggest two conclusions. From the perspective of learning target concepts, asking subjects to develop their own representation may not hurt those subjects who gain a sufficient understanding of the possibilities of abstract representation. The risks are much greater for less able subjects because, if they develop a representation that is inadequate for expressing the target concepts, they will use those concepts less or not at all. From the perspective of coaching subjects as they diagram their analysis of texts, a predefined representation has significant advantages. If it is appropriately expressive for the task, it provides a common language and clearer shared meaning between the subject and the coach. It also enables the coach to understand subjects' analysis more easily, and to evaluate it more effectively against the

  17. Students’ scientific production: a proposal to encourage it.

    Science.gov (United States)

    Corrales-Reyes, Ibraín Enrique; Dorta-Contreras, Alberto Juan

    2018-01-31

    The scientific production of medical students in Latin America, is poor and below their potential. The reason for this is the low theoretical and practical knowledge of scientific writing, a low margin for new knowledge generation, a heavy academic and clinical load, and the expected profile of the medical school graduate. In the present short communication, we propose teaching courses in research methodology, scientific writing in English and Spanish, a personalized search for students and mentors with research aptitudes. Also, we propose academic and material stimuli for publishing, rewards for the best papers made by students and the development and support of scientific student journals. Other proposals are the requirement to publish a paper for graduation, and sharing the most outstanding experiences.

  18. Funding scientific open access

    International Nuclear Information System (INIS)

    Canessa, E.; Fonda, C.; Zennaro, M.

    2006-11-01

    In order to reduce the knowledge divide, more Open Access Journals (OAJ) are needed in all languages and scholarly subject areas that exercise peer-review or editorial quality control. To finance needed costs, it is discussed why and how to sell target specific advertisement by associating ads to given scientific keywords. (author)

  19. [The representation of scientific research through a poster].

    Science.gov (United States)

    Dupin, Cécile-Marie

    2013-12-01

    The poster is a medium of scientific communication. When presented in public, it optimises the value of an original research approach. The poster sessions are devoted to one-to-one exchanges with peers on the subject of the research. The poster can help to integrate scientific knowledge into the nursing decision-making process.

  20. Scientific Instruments and Epistemology Engines

    Czech Academy of Sciences Publication Activity Database

    Dvořák, Tomáš

    2012-01-01

    Roč. 34, č. 4 (2012), s. 529-540 ISSN 1210-0250 R&D Projects: GA ČR(CZ) GAP401/11/2338 Institutional support: RVO:67985955 Keywords : material culture of science * scientific instruments * epistemology engines * experimental systems Subject RIV: AA - Philosophy ; Religion

  1. Experimental analysis of temperature profiles in ceramic brickwork elements subjected to high temperatures

    Directory of Open Access Journals (Sweden)

    Maciá, M. E.

    2013-12-01

    Full Text Available This article discusses heat transfer through a brick element in order to know the thermal behavior of onedimensional brickwork masonry samples exposed to high temperatures. The object of the tests is to build time-temperature curves according to different thermal steps in transient to experimentally determine the temperature profiles in the interior of a wall. Through this study, it is possible to demonstrate absolute moisture of a factory item from 300 °C (variation of temperatures in the interior of the element, avoid the associated phenomenon of evaporation of water during the thermal process as well as to obtain profiles of temperatures that help calculate the cross section of a factory element subjected to high temperatures.En este artículo se analiza la transferencia de calor a través de un elemento de fábrica de ladrillo con el fin de conocer el comportamiento térmico de secciones de fábrica unidimensionales expuestas a altas temperaturas. El objeto de los ensayos es construir curvas tiempo-temperatura en función de diversos escalones térmicos en régimen transitorio para determinar experimentalmente los perfiles de temperatura en el interior de un muro. A través de este estudio es posible evidenciar el contenido de humedad absoluta de un elemento de fábrica a partir de los 300 ºC (variación de las temperaturas en el interior del elemento, evitar el fenómeno asociado de la evaporación del agua durante el proceso térmico así como obtener perfiles de temperaturas que ayuden a calcular la sección eficaz de un elemento de fábrica sometido a altas temperaturas.

  2. The Influence of an undergraduate scientific initiation programme onn the professional profile of new physicians.

    Science.gov (United States)

    Joaquim Teles Cyrillo, Raphael; Setúbal, Sérgio; da Silva Júnior, Cyro Teixeira; Guillermo Coca Velarde, Luis; de Mattos, Ana Carolina Musser Tavares; Bezerra Cardoso, Renato Bergallo; Cardoso, Gilberto Perez

    2010-01-01

    This paper studies the influence of a Scientific Initiation Programme (SIP) on the professional profile of new doctors from a Brazilian university. Evaluate fifty-two new doctors divided into two groups matched by sex, age and academic performance and differing only in participation in the SIP. Professional and socioeconomic data were collected, including schooling of parents; average income before, during and after the medical course; current professional situation; results of exams for civil servant recruitment; and titles and degrees obtained after graduation. Significant differences were found only in civil servant recruitment exam results (p=0.0098) and in income after graduation (p=0.02), which were both higher in the non-SIP group. Only one doctor got a M.Sc. degree after graduation, but many of them in both groups obtained technical titles, and had papers presented at congresses or published. Apparently, taking part in a SIP led to lower income and worse civil servant recruitment exam results. However, this may only reflect a transient phase in a long-term process. New research currently under way will answer this remaining question, now that more time has elapsed since graduation. Rev Port Pneumol 2010; XVI (5): 797-808. © 2010 Sociedade Portuguesa de Pneumologia/SPP.

  3. The admissibility of offender profiling in courtroom: a review of legal issues and court opinions.

    Science.gov (United States)

    Bosco, Dario; Zappalà, Angelo; Santtila, Pekka

    2010-01-01

    What is the future of Offender Profiling? Is it an important field of forensic science or is it only a glamorous art? After the trilogy "Daubert-Joiner-Kumho" and after the last version, in 2009, of the Federal Rules of Evidence (F.R.E.), the opinion of American Courts concerning the admissibility of scientific evidence has changed, and the questions above can now have new answers. The change is closely tied to the perceived difference between hard and soft sciences and, in this way, the new gatekeeping role of the Courts also concerns whether offender profiling can be regarded as scientific evidence and if offender profiling should be admitted in the Courtroom as scientific evidence. In this work we present a comprehensive review concerning the most important Court opinions in U.S.A, U.K., Canada and Australia, about reliability and admissibility of offender profiling, in its different forensic application, as scientific evidence, and we suggest how and when an expert witness in the field of offender profiling can, in the light of these opinions, be admitted in Court.

  4. The Effects of 6 Isocaloric Meals on Body Weight, Lipid Profiles, Leptin, and Adiponectin in Overweight Subjects (BMI > 25

    Directory of Open Access Journals (Sweden)

    Zeynab Hatami Zargaran

    2014-06-01

    Full Text Available Background: It seems that meal frequency is negatively related to body weight, but the relationship between meal frequency and weight loss is not clearly known yet. Objectives: The present study aimed to investigate whether 6 isocaloric meals affected body weight, lipid profiles, leptin, and adiponectin in overweight subjects. Methods: The present randomized controlled trial was conducted on 90 overweight subjects in 3 months. The subjects were randomly divided into two groups. The control group continued their normal diet, while the intervention group was required to follow a 6 isocaloric meal diet instead of their previous meal pattern (3 meals and 2 snacks. The planned reduced calorie diets for both groups were identical, except for meal pattern. Blood samples were analyzed prior to and at the end of the study for total cholesterol, triglyceride, HDL-C, LDL-C, leptin, and adiponectinn concentrations. Paired t-test was used for comparison of the measurements before and after the study in each group. Besides, independent t-test was used for comparison of the measurements between the groups. P value less than 0.05 was considered as statistically significant. Results: The mean age of the participants was 36.38 ± 9.7 in the intervention group and 37.6 ± 10.9 in the control group. In comparison to the control group, the intervention group showed a significant decrease in total cholesterol (P < 0.001, LDL-C (P < 0.001, BMI (P < 0.001, triglyceride (P < 0.001, and leptin (P = 0.002 and a significant increase in HDL (P < 0.001 and adiponectin (P = 0.031. Conclusions: The 6 isocaloric meal pattern led to a reduction in BMI, lipid profiles (total cholesterol, LDL-C, triglyceride, and leptin concentrations and an increase in HDL and adiponectin compared to the normal diet.

  5. Is risk analysis scientific?

    Science.gov (United States)

    Hansson, Sven Ove; Aven, Terje

    2014-07-01

    This article discusses to what extent risk analysis is scientific in view of a set of commonly used definitions and criteria. We consider scientific knowledge to be characterized by its subject matter, its success in developing the best available knowledge in its fields of study, and the epistemic norms and values that guide scientific investigations. We proceed to assess the field of risk analysis according to these criteria. For this purpose, we use a model for risk analysis in which science is used as a base for decision making on risks, which covers the five elements evidence, knowledge base, broad risk evaluation, managerial review and judgment, and the decision; and that relates these elements to the domains experts and decisionmakers, and to the domains fact-based or value-based. We conclude that risk analysis is a scientific field of study, when understood as consisting primarily of (i) knowledge about risk-related phenomena, processes, events, etc., and (ii) concepts, theories, frameworks, approaches, principles, methods and models to understand, assess, characterize, communicate, and manage risk, in general and for specific applications (the instrumental part). © 2014 Society for Risk Analysis.

  6. Better Renal Resistive Index Profile in Subjects with Beta Thalassemia Minor .

    Science.gov (United States)

    Basut, Fahrettin; Keşkek, Şakir Özgür; Gülek, Bozkurt

    2018-05-03

    Beta thalassaemia minor is a common genetic disorder without any characteristic symptoms except mild anemia. It is found to be associated with some cardiovascular risk factors such as insulin resistance and diabetes mellitus. The renal resistive index (RRI) is a measure of renal arterial resistance to blood flow. The aim of this study was to evaluate the renal resistive index in subjects with beta thalassaemia minor (BTM). A total of 253 subjects were included in this cross-sectional study. The study group consisted of 148 subjects with BTM and the control group consisted of 105 healthy subjects. Beta thalassaemia minor was diagnosed by complete blood count and hemoglobin electrophoresis. Blood pressure measurement and biochemical tests were performed. Renal resistive index of all subjects was measured using renal Doppler ultrasonography. Subjects with beta thalassemia minor had lower renal resistive indices compared to healthy subjects (0.58 ± 0.04 vs. 0.60 ± 0.06, p = 0.0016). Additionally, the RRI levels of subjects with BTM were correlated with systolic blood pressure (p = 0.017, r = 0.194). In this study, lower renal resistive index was found in subjects with BTM. This may be associated with decreased vascular resistance and blood viscosity in these subjects. ©2018The Author(s). Published by S. Karger AG, Basel.

  7. SCIENTIFIC STUDY OF NATURE AND SCIENTIFIC STUDY OF CULTURE: INTE-GRATION TREND, PRACTICAL VALUE

    Directory of Open Access Journals (Sweden)

    Fokina Zoya Titovna

    2017-03-01

    Full Text Available This article deals with a topic of interest : studying the expanding and deepening trend of integration of natural, technical, social and humanities fields of scientific knowledge. The point of absolute opposition between the sciences dealing with nature and those dealing with culture is subjected to criticism, the forms of integration of scientific knowledge are identified: mathematization, formalization, computerization of knowledge; philosophization/dialectization and environmentalization of the scientific knowledge. It is noted that such areas of scientific knowledge as synergetics, cybernetics, system theory, information technology, sociosynergetics, historical informatics, cliometrics, informatics for economics, evolutionary economics, human ecology, etc. Many scientific fields appear on the border between the science, technology and mathematics, and social and humanities studies, while the sharp borders between the natural sciences and cultural sciences tend to disappear, although specifics of studying the social reality still exists. Within the context of integration of sciences, comprehensive approach, synergetics, cybernetics, and mathematical model approach are analyzed. The philosophy of technology, and environmental problems, which are caused by the development of technological civilization, are studied. Practical value of integration processes in science is identified. The studied data is addressed to the specialists who are interested in the modern processes of integration of sciences, and modern issues of scientific and technical development of humanity, survival of humanity under the conditions of increasing technological understanding of the nature.

  8. Analysing Scientific Collaborations of New Zealand Institutions using Scopus Bibliometric Data

    OpenAIRE

    Aref, Samin; Friggens, David; Hendy, Shaun

    2017-01-01

    Scientific collaborations are among the main enablers of development in small national science systems. Although analysing scientific collaborations is a well-established subject in scientometrics, evaluations of scientific collaborations within a country remain speculative with studies based on a limited number of fields or using data too inadequate to be representative of collaborations at a national level. This study represents a unique view on the collaborative aspect of scientific activi...

  9. Measuring scientific research in emerging nano-energy field

    Science.gov (United States)

    Guan, Jiancheng; Liu, Na

    2014-04-01

    The purpose of this paper is to comprehensively explore scientific research profiles in the field of emerging nano-energy during 1991-2012 based on bibliometrics and social network analysis. We investigate the growth pattern of research output, and then carry out across countries/regions comparisons on research performances. Furthermore, we examine scientific collaboration across countries/regions by analyzing collaborative intensity and networks in 3- to 4-year intervals. Results indicate with an impressively exponential growth pattern of nano-energy articles, the world share of scientific "giants," such as the USA, Germany, England, France and Japan, display decreasing research trends, especially in the USA. Emerging economies, including China, South Korea and India, exhibit a rise in terms of the world share, illustrating strong development momentum of these countries in nano-energy research. Strikingly, China displays a remarkable rise in scientific influence rivaling Germany, Japan, France, and England in the last few years. Finally, the scientific collaborative network in nano-energy research has expanded steadily. Although the USA and several major European countries play significantly roles on scientific collaboration, China and South Korea exert great influence on scientific collaboration in recent years. The findings imply that emerging economies can earn competitive advantages in some emerging fields by properly engaging a catch-up strategy.

  10. From Comparison Between Scientists to Gaining Cultural Scientific Knowledge. Leonardo and Galileo

    Science.gov (United States)

    Galili, Igal

    2016-03-01

    Physics textbooks often present items of disciplinary knowledge in a sequential order of topics of the theory under instruction. Such presentation is usually univocal, that is, isolated from alternative claims and contributions regarding the subject matter in the pertinent scientific discourse. We argue that comparing and contrasting the contributions of scientists addressing similar or the same subject could not only enrich the picture of scientific enterprise, but also possess a special appealing power promoting genuine understanding of the concept considered. This approach draws on the historical tradition from Plutarch in distant past and Koyré in the recent history and philosophy of science. It gains a new support in the discipline-culture structuring of the physics curriculum, seeking cultural content knowledge (CCK) of the subject matter. Here, we address two prominent individuals of Italian Renaissance, Leonardo and Galileo, in their dealing with issues relevant for introductory science courses. Although both figures addressed similar subjects of scientific content, their products were essentially different. Considering this difference is educationally valuable, illustrating the meaning of what students presently learn in the content knowledge of mechanics, optics and astronomy, as well as the nature of science and scientific knowledge.

  11. 2003 Scientific Technological Report

    International Nuclear Information System (INIS)

    Prado Cuba, A.; Gayoso Caballero, C.; Robles Nique, A.; Olivera Lescano, P.

    2004-08-01

    This annual scientific-technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2003. This report includes 54 papers divided in 9 subject matters: physics and nuclear chemistry, nuclear engineering, materials science, radiochemistry, industrial applications, medical applications, environmental applications, protection and radiological safety, and management aspects

  12. Ferulic Acid Supplementation Improves Lipid Profiles, Oxidative Stress, and Inflammatory Status in Hyperlipidemic Subjects: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

    Directory of Open Access Journals (Sweden)

    Akkarach Bumrungpert

    2018-06-01

    Full Text Available Ferulic acid is the most abundant phenolic compound found in vegetables and cereal grains. In vitro and animal studies have shown ferulic acid has anti-hyperlipidemic, anti-oxidative, and anti-inflammatory effects. The objective of this study is to investigate the effects of ferulic acid supplementation on lipid profiles, oxidative stress, and inflammatory status in hyperlipidemia. The study design is a randomized, double-blind, placebo-controlled trial. Subjects with hyperlipidemia were randomly divided into two groups. The treatment group (n = 24 was given ferulic acid (1000 mg daily and the control group (n = 24 was provided with a placebo for six weeks. Lipid profiles, biomarkers of oxidative stress and inflammation were assessed before and after the intervention. Ferulic acid supplementation demonstrated a statistically significant decrease in total cholesterol (8.1%; p = 0.001, LDL-C (9.3%; p < 0.001, triglyceride (12.1%; p = 0.049, and increased HDL-C (4.3%; p = 0.045 compared with the placebo. Ferulic acid also significantly decreased the oxidative stress biomarker, MDA (24.5%; p < 0.001. Moreover, oxidized LDL-C was significantly decreased in the ferulic acid group (7.1%; p = 0.002 compared with the placebo group. In addition, ferulic acid supplementation demonstrated a statistically significant reduction in the inflammatory markers hs-CRP (32.66%; p < 0.001 and TNF-α (13.06%; p < 0.001. These data indicate ferulic acid supplementation can improve lipid profiles and oxidative stress, oxidized LDL-C, and inflammation in hyperlipidemic subjects. Therefore, ferulic acid has the potential to reduce cardiovascular disease risk factors.

  13. THE PROFILE OF THE ACCOUNTING RESEARCH ABOUT IFRS: A BIBLIOMETRIC REVIEW OF INTERNATIONAL ARTICLES ON THE SUBJECT

    Directory of Open Access Journals (Sweden)

    Andressa Iovine Martins

    2012-12-01

    Full Text Available The main objective of this article is to identify what is currently being researched in the area of International Financial Reporting Standards (IFRS around the world; who is carrying on such researches; which researches has caused stronger impact; which journals shows more articles about this issue and the ones that cause more impacts; the time frames and places this subject is more often produced. The applied methodology was based on the metrics precepts, using as data base platform the Web of Science (WoS of Citation Indexes from the Institute for Scientific Information – ISI – Citation Indexes. It was found 150 articles for the research lookout of “International Financial Reporting Standards” and 147 for “IFRS” found in the four main categories of WoS related to that subject. According to the two used terms for research, the result was quite conflicting. It was observed that the more productive writers are not necessarily the most influential ones, which also occurred in regard to periodic publications. The large majority of the production occurred from 2006 on, and the countries that stood out more, in quantity terms, were the United States of America, Germany, Australia and England.

  14. Relativism and the social scientific study of medicine.

    Science.gov (United States)

    Risjord, M

    1993-04-01

    Does the social scientific study of medicine require a commitment to relativism? Relativism claims that some subject (e.g., knowledge claims or moral judgments) is relative to a background (e.g., a culture or conceptual scheme) and that judgments about the subject are incommensurable. Examining the concept of success as it appears in orthodox and nonorthodox medical systems, we see that judgments of success are relative to a background medical system. Relativism requires the social scientific study of medicine to be value free in the sense that a medical system must be described without evaluating its elements. When social scientists do evaluate the successfulness of a nonorthodox medical system, they give a crucial role to the nonorthodox conception of success. This strategy does not vitiate value-freedom and it entails a relativism about success. The social scientific study of medicine, therefore, does require relativism in the form of a relativism about success.

  15. Subject-based steroid profiling and the determination of novel biomarkers for DHT and DHEA misuse in sports.

    Science.gov (United States)

    Van Renterghem, Pieter; Van Eenoo, Peter; Sottas, Pierre-Edouard; Saugy, Martial; Delbeke, Frans

    2010-01-01

    Doping with natural steroids can be detected by evaluating the urinary concentrations and ratios of several endogenous steroids. Since these biomarkers of steroid doping are known to present large inter-individual variations, monitoring of individual steroid profiles over time allows switching from population-based towards subject-based reference ranges for improved detection. In an Athlete Biological Passport (ABP), biomarkers data are collated throughout the athlete's sporting career and individual thresholds defined adaptively. For now, this approach has been validated on a limited number of markers of steroid doping, such as the testosterone (T) over epitestosterone (E) ratio to detect T misuse in athletes. Additional markers are required for other endogenous steroids like dihydrotestosterone (DHT) and dehydroepiandrosterone (DHEA). By combining comprehensive steroid profiles composed of 24 steroid concentrations with Bayesian inference techniques for longitudinal profiling, a selection was made for the detection of DHT and DHEA misuse. The biomarkers found were rated according to relative response, parameter stability, discriminative power, and maximal detection time. This analysis revealed DHT/E, DHT/5β-androstane-3α,17β-diol and 5α-androstane-3α,17β-diol/5β-androstane-3α,17β-diol as best biomarkers for DHT administration and DHEA/E, 16α-hydroxydehydroepiandrosterone/E, 7β-hydroxydehydroepiandrosterone/E and 5β-androstane-3α,17β-diol/5α-androstane-3α,17β-diol for DHEA. The selected biomarkers were found suitable for individual referencing. A drastic overall increase in sensitivity was obtained. The use of multiple markers as formalized in an Athlete Steroidal Passport (ASP) can provide firm evidence of doping with endogenous steroids. Copyright © 2010 John Wiley & Sons, Ltd.

  16. Techniques and tools for measuring energy efficiency of scientific software applications

    International Nuclear Information System (INIS)

    Abdurachmanov, David; Elmer, Peter; Eulisse, Giulio; Knight, Robert; Niemi, Tapio; Pestana, Gonçalo; Khan, Kashif; Nurminen, Jukka K; Nyback, Filip; Ou, Zhonghong

    2015-01-01

    The scale of scientific High Performance Computing (HPC) and High Throughput Computing (HTC) has increased significantly in recent years, and is becoming sensitive to total energy use and cost. Energy-efficiency has thus become an important concern in scientific fields such as High Energy Physics (HEP). There has been a growing interest in utilizing alternate architectures, such as low power ARM processors, to replace traditional Intel x86 architectures. Nevertheless, even though such solutions have been successfully used in mobile applications with low I/O and memory demands, it is unclear if they are suitable and more energy-efficient in the scientific computing environment. Furthermore, there is a lack of tools and experience to derive and compare power consumption between the architectures for various workloads, and eventually to support software optimizations for energy efficiency. To that end, we have performed several physical and software-based measurements of workloads from HEP applications running on ARM and Intel architectures, and compare their power consumption and performance. We leverage several profiling tools (both in hardware and software) to extract different characteristics of the power use. We report the results of these measurements and the experience gained in developing a set of measurement techniques and profiling tools to accurately assess the power consumption for scientific workloads. (paper)

  17. IPEN (Instituto de Pesquisas Energeticas e Nucleares) technical-scientific production - 1995-1996

    International Nuclear Information System (INIS)

    1998-03-01

    The biannual report of 1995-1996 of IPEN (Instituto de Pesquisas Energeticas e Nucleares) - Brazilian organization - presents the technical and scientific production accomplished in the period - 975 woks - and introduces the next main topics: articles of periodicals; scientific events - complete texts; dissertations and thesis; scientific events - complete texts - communications, summaries and panels; IPEN publications; books; authors index; scientific events index; subjects index; and periodicals index

  18. Scientific Technological Report 2002

    International Nuclear Information System (INIS)

    Gayoso C, C.; Cuya G, T.; Robles N, A.; Prado C, A.

    2003-07-01

    This annual scientific-technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2002. This report includes 58 papers divided in 10 subject matters: physics and nuclear chemistry, nuclear engineering, materials, industrial applications, biological applications, medical applications, environmental applications, protection and radiological safety, nuclear safety, and management aspects

  19. Achievement Goal Orientations and Subjective Well-Being: A Person-Centred Analysis

    Science.gov (United States)

    Tuominen-Soini, Heta; Salmela-Aro, Katariina; Niemivirta, Markku

    2008-01-01

    This study examined whether students with different achievement goal orientation profiles differ in terms of subjective well-being (i.e., self-esteem, depressive symptoms, school-related burnout, and educational goal appraisals). Six groups of students with unique motivational profiles were identified. Observed differences in subjective well-being…

  20. IPEN Scientific and technical publications 1956-1981

    International Nuclear Information System (INIS)

    1983-01-01

    The Instituto de Pesquisas Energeticas e Nucleares - IPEN (Energy Research Institute) from Sao Paulo, Brazil, was founded in 1956. Since its foundation, the main objectives of IPEN has been to undertake research and development into the peaceful uses of nuclear energy and to train scientific personnel to post-graduate level. The IPEN Scientific and Technical Publication - IPEN/SP, is a system developed at IPEN. Its purpose has been to generate a data base identifying the technical and scientific literature produced by IPEN staff members, published either in the Institute's series or in others brazilian and foreign publications. Documents cited in this jubilee edition include those in which IPEN staff members were authors or co-authors; document published by foreign research visitors while working at IPEN facilities; theses prepared by IPEN staff and reports in which IPEN is a corporate author. The IPEN technical publications reflect the main fields of research persuaded by the Institute, namely nuclear physics radiochemistry, chemical engineering, nuclear metallurgy and engineering and finally medical and industrial applications of radioisotopes. This present volume, published under the new title of IPEN - Scientific and Technical Publications, is a cumulative edition, to celebrate the 25th. anniversary of IPEN. In this jubilee edition, 1345 document published by IPEN staff are cited, following the main subject heading of INIS Subject Categories. (author)

  1. Joseph Henry's Conception of Scientific Knowledge

    Science.gov (United States)

    Theerman, Paul

    1997-04-01

    Joseph Henry, America's premier physicist and physics teacher in the mid-nineteenth century, had decided views of scientific knowledge. These were expressed in two ways. First of all, scientific knowledge led to moral betterment. Thus the study of science was a morally good thing. This was not only because it led to the contemplation of God's creation, which was a standard reason justifying the study of science dating from the Scientific Revolution and even earlier. More importantly, the study of science itself was a moral discipline, imparting to scientists the habits and virtues of truthfulness, respect for others, care and diligence, and the discernment of meaningful patterns from experience. The moral ideals of science were expressed most strongly in Henry's upholding the international "Republic of Science"; conversely, cheapening science was a sign of moral failure. Second, for Henry and his generation, science provided a path to sure truth, separate from falsehood of both the politics and the quackery that characterized mid-century public life. Henry promoted this in his championing of the Smithsonian Institution a scientific establishment, against the ideas of others who wanted to make it a literary establishment or a training school for teachers. For Henry, the Smithsonian's scientific reputation would be established by relying on careful peer review in its publications, and supporting established scientists to write authoritative popular works. The purpose of both these activities was to raise the profile of science in the United States and further establish science and the scientific method as a guide to public life.

  2. Effects of extra virgin olive oil supplementation at two different low doses on lipid profile in mild hypercholesterolemic subjects: a randomised clinical trial.

    Science.gov (United States)

    Violante, B; Gerbaudo, L; Borretta, G; Tassone, F

    2009-11-01

    Olive oil, the principal fat of Mediterranean Diet, is known to improve several cardiovascular risk factors at relatively high doses together with intensive modifications of dietary habits. Since this is hard to obtain in the long term, an intervention with encapsulated oil supplements might be more feasible. Aim of this preliminary study was to investigate the effects of the supplementation of a moderate amount of encapsulated extra virgin olive oil vs a lower dose in mildly hypercholesterolemic subjects, as part of their established diet, on blood lipid profile. A prospective randomized study was performed. Thirty-four mildly hypercholesterolemic subjects [age, mean+/-SD: 46+/-7 yr; total cholesterol (TC): 235+/-28 mg/dl] were randomly assigned to receive 2 g (group A) or 4 g (group B) per os of extra-virgin olive oil for 3 months. TC, triglycerides (TG), LDL cholesterol, HDL cholesterol, apolipoprotein A1 (Apo-AI), apolipoprotein B (Apo-B), and atherogenic index of plasma (AIP) were evaluated at the beginning and at the end of the study. In group B, but not in group A, a significant reduction of Apo-B values (7%) was observed; TG concentrations showed a trend towards reduction and Apo-A1 values a trend towards increase (9%). A significant decrease in Apo-B/Apo-A1 ratio (pgroup B. Extra virgin olive oil supplementation significantly decreased AIP from baseline in group B (pvirgin olive oil, in mildly hypercholesterolemic subjects, is associated to favorable modifications of the plasmatic lipid profile.

  3. Founder of a scientific school on plasma

    International Nuclear Information System (INIS)

    Anon

    2003-01-01

    The academician Mikhail Aleksandrovitch Leontovitch is a physicist-theorist of a wide profile (physical optics, oscillation theory, acoustics, statistical physics, thermodynamics), who became the founder of the largest scientific schools on the radiophysics and plasma physics. Namely due to his effective leadership in developing the theory our theoretical studies on the controlled thermonuclear synthesis reached high level and facilitated the success of the experiment [ru

  4. Fatty acid profile in vertical strata of elephant grass subjected to intermittent stocking

    Directory of Open Access Journals (Sweden)

    KAMILA M. DIAS

    2017-08-01

    Full Text Available ABSTRACT The milk and meat from animals with a pasture-based diet have higher proportions of CLA and C18:3 and lower omega-6:omega-3 ratios than products from animals with diets based on corn silage and concentrate. However, most of the published studies have evaluated fatty acid profiles in temperate climate grasses and the literature with tropical grasses is scarce. Thus, the aim of this study was to evaluate the morphological and fatty acid compositions in the vertical strata of elephant grass (Pennisetum purpureum Schum. swards subjected to grazing heights (90 or 120 cm pre-grazing heights and levels of defoliation (50% or 70% removal of the initial pre-grazing height. There were no interactions among pre-grazing height, the level of defoliation and grazing stratum. However, higher proportion of C18:3 (58% and 63% was found in the 90-cm swards and in the half upper stratum. A higher proportion of C18:3 was associated with a higher leaf proportion and crude protein content. Thus, the upper stratum of sward or a grazing management scheme (e.g. first-last stocking resulting in a higher proportion of leaves and crude protein both provide higher proportions of C18:3 to animals grazing in elephant grass swards.

  5. Medical elementology as a new scientific discipline

    International Nuclear Information System (INIS)

    Zaichick, V.

    2006-01-01

    All legitimate scientific disciplines are characterized by: (1) the clear definition of subjects of the study and its corresponding clear-cut name, (2) some accepted postulates, (3) set of research methods, (4) methods of quality control and processing of the obtained information, and (5) specific terminology and definitions. The inaccuracies and uncertainties in medical elementology as a new scientific discipline are discussed and some corresponding statements are made. Another and no less important problem of medical elementology is the critical unsatisfactory reproducibility of data. The complex arrangements required for the harmonization of data acquired for studies in medical elementology are offered. Main strategic aims and tactical tasks of the new scientific discipline are outlined. (author)

  6. Human subjects and experimental irradiation

    International Nuclear Information System (INIS)

    Rosen, R.

    1985-01-01

    In recent years the public has expressed concern about the use of human subjects in scientific research. Some professional institutions have adopted codes of practice to guide them in this matter. At the University of New South Wales, where human subjects are used in teaching and research programmes, a committee ensures that high ethical standards are maintained. As the volunteer subjects do not gain any benefit themselves from the procedures, their level of risk is kept low. One type of procedure in which risk is becoming quantifiable, is the irradiation of human subjects. To assist peer review groups, the ICRP, WHO and the National Health and Medical Research Council have enunciated principles which should be followed in the irradiation of human volunteer subjects. In general the role of the Committee is advisory to protect the rights of the investigator, the subject, and the institution. Some of the inherent problems are discussed

  7. Knowledge Management and Analysis of Scientific Biotechnology Trends in Venezuela

    Directory of Open Access Journals (Sweden)

    Maria Fatima Ebole Santana

    2012-03-01

    Full Text Available This paper presents a study on knowledge management and analysis of scientific Biotechnology trends in Venezuela, providing an overview of the science profile as well as regional development and its relation to issues of topics covered by Biotechnology based on the analysis of scientific publications for the period of 1995 to 2010. The survey was accomplished in database ISI/Web of Science using 60 terms selected by experts in Biotechnology and 803 register has been organized. Scientific indicators were produced using data/ text mining tools. It was possible to find a greater number of scientific publications in areas such as Ecology and Health, showing a greater frequency in these terms: DNA, PCR and Biodiversity. Results pointed out The United States of America as the main foreign partner-country of scientific publications followed by Spain and France. It was possible to verify cooperation network with others Latin American countries: Brazil, Colombia and Chile.

  8. The heart field effect: Synchronization of healer-subject heart rates in energy therapy.

    Science.gov (United States)

    Bair, Christine Caldwell

    2008-01-01

    Recent health research has focused on subtle energy and vibrational frequency as key components of health and healing. In particular, intentional direction of bioenergy is receiving increasing scientific attention. This study investigates the effect of the healer's electromagnetic (EM) heart field upon subjects during energy healing as measured by synchronization of heart rates and scores on a Subjective Units of Distress (SUD) scale and a Profile of Mood States (POMS) inventory. A nonequivalent pretest-posttest design was used based on heart rate comparisons between healer and subject and correlated with pre-and posttest SUD and POMS scores. Subjects included those who sat within the 3- to 4-foot "strong" range of the independent variable, the healer's heart field, while performing self-application of WHEE (the wholistic hybrid derived from EMDR [eye movement desensitization and reprocessing], and EFT [emotional freedom technique]), a meridian-based tapping technique (n=50); and those who performed the same process beyond the 15- to 18-foot range of the healer's EM heart field (n=41). The dependent variables were heart rate, SUD, and POMS inventory. All subjects completed these measures within 1 hour. Study results showed statistically significant heart-rate synchronization with the intervention population. In addition, SUD and POMS scores demonstrated considerably more improvement than in the control population, indicating additional benefit beyond the meridian-based therapies, such as WHEE, alone. Additional findings and future research recommendations are presented in this article.

  9. Subjective State, Blood Pressure, and Behavioral Control Changes Produced by an "Energy Shot"

    Science.gov (United States)

    Marczinski, Cecile A; Stamates, Amy L; Ossege, Julianne; Maloney, Sarah F; Bardgett, Mark E; Brown, Clifford J

    2014-06-01

    Background: Energy drinks and energy shots are popular consumer beverages that are advertised to increase feelings of alertness. Typically, these products include high levels of caffeine, a mild psychostimulant drug. The scientific evidence demonstrating the specific benefits of energy products to users in terms of subjective state and objective performance is surprisingly lacking. Moreover, there are rising health concerns associated with the use of these products. Therefore, the purpose of this study was to investigate the acute effects of a popular energy shot (5-Hour Energy ® ) on subjective and objective measures that were assessed hourly for 6 hours following consumption. Methods: Participants ( n =14) completed a three-session study where they received the energy shot, a placebo control, and no drink. Following dose administration, participants completed subjective Profile of Mood States ratings hourly for 6 hours. Participants also repeatedly completed a behavioral control task (the cued go/no-go task) and provided blood pressure and pulse rate readings at each hour. Results: Consumption of the energy shot did improve subjective state, as measured by increased ratings of vigor and decreased ratings of fatigue. However, the energy shot did not alter objective performance, which worsened over time. Importantly, the energy shot elevated both systolic and diastolic blood pressure. Conclusions: Consumption of one energy shot may only result in modest benefits to subjective state. Individuals with preexisting hypertension or other medical conditions should be cautious about using these new consumer products.

  10. IPEN scientific and technical publications 1984-1986

    International Nuclear Information System (INIS)

    1988-01-01

    The Instituto de Pesquisas Energeticas e Nucleares - IPEN (Energy Research Institute) from Sao Paulo, Brazil, was founded in 1956. Since its foundation, the main objectives of IPEN has been to undertake research and development into the peaceful uses of nuclear energy and to train scientific personnel to post-graduate level. The IPEN Scientific and Technical Publication - IPEN/STP, is a system developed at IPEN. Its purpose has been to generate a data base identifying the technical and scientific literature produced by IPEN staff members, published either in the Institute's series or in others brazilian and foreign publications. Documents cited in this 1984-1986 supplement include those in which IPEN staff members were authors or co-authors; document published by foreign research visitors while working at IPEN facilities; theses prepared by IPEN staff and reports in which IPEN is a corporate author. The IPEN technical publications reflect the main fields of research persuaded by the Institute, namely nuclear physics radiochemistry, chemical engineering, nuclear metallurgy and engineering and finally medical and industrial applications of radioisotopes. In this 1984-1986 supplement 458 document published by IPEN staff are cited, following the main subject heading of INIS Subject Categories. (author)

  11. IPEN Scientific and technical publications 1982-1983

    International Nuclear Information System (INIS)

    1984-01-01

    The Instituto de Pesquisas Energeticas e Nucleares - IPEN (Energy Research Institute) from Sao Paulo, Brazil, was founded in 1956. Since its foundation, the main objectives of IPEN has been to undertake research and development into the peaceful uses of nuclear energy and to train scientific personnel to post-graduate level. The IPEN Scientific and Technical Publication - IPEN/STP, is a system developed at IPEN. Its purpose has been to generate a data base identifying the technical and scientific literature produced by IPEN staff members, published either in the Institute's series or in others brazilian and foreign publications. Documents cited in this 1982-1983 supplement include those in which IPEN staff members were authors or co-authors; document published by foreign research visitors while working at IPEN facilities; theses prepared by IPEN staff and reports in which IPEN is a corporate author. The IPEN technical publications reflect the main fields of research persuaded by the Institute, namely nuclear physics radiochemistry, chemical engineering, nuclear metallurgy and engineering and finally medical and industrial applications of radioisotopes. In this 1982-1983 supplement 131 document published by IPEN staff are cited, following the main subject heading of INIS Subject Categories. (author)

  12. Reliability and Validity of a Nepalese Version of the Oral Health Impact Profile for Edentulous Subjects.

    Science.gov (United States)

    Shrestha, Bidhan; Niraula, Surya Raj; Parajuli, Prakash K; Suwal, Pramita; Singh, Raj Kumar

    2018-06-01

    To assess the reliability and to validate the translated Nepalese version of the Oral Health Impact Profile (OHIP-EDENT-N) in Nepalese edentulous subjects. The international guidelines for translation and cross-cultural adaption of OHIP-EDENT were followed, and a Nepalese version of the questionnaire was adapted for this study. Eighty-eight completely edentulous subjects were then selected for the study and completed their responses for the questionnaire. The reliability of the OHIP-EDENT-N was evaluated using internal consistency. Validity was assessed as construct and convergent validity. Construct validity was determined using exploratory factor analysis (EFA). The correlation between OHIP-EDENT-N subscale scores and the global question was investigated to test the convergent validity. Cronbach's alpha for the total score of OHIP-EDENT-N was 0.78. Construct validity was assessed by factor analysis: 70.196% of the variance was accountable to five factors extracted from the factor analysis. Factor loadings above 0.40 were noted for all items. In terms of convergent validity, significant correlations could be established between OHIP-EDENT-N and global questions. This study has been able to establish the reliability and validity of the OHIP-EDENT-N, and OHIP-EDENT-N can be a considered a reliable tool to assess the oral health related quality of life in the Nepalese edentulous population. © 2016 by the American College of Prosthodontists.

  13. Pseudo-Scientific Information: Reasons of Spread and Premises of Vitality

    Directory of Open Access Journals (Sweden)

    Valdas Pruskus

    2011-04-01

    Full Text Available The phenomenon of pseudo-scientific information, the reasons of its spread and premises of its vitality are discussed in the paper. Pseudo-scientific information is understandable as an attempt to suit a demand, which exists in society, while providing a simple answer to a question, which an individual or society is concerned about, and that answer is not sustained by scientific research. It is showed that the rise and spread of pseudo-scientific information in society are conditioned by objective reasons. Firstly, the lack of information concerning a subject which is significant for society. Secondly, the lack of information for a particular individual (social group concerning a substantial subject. Thirdly, fast spread of scientific and technical inventions and penetration of technological innovations into various spheres of life the understanding of which demands an appropriate informal “processing”, i e it demands provision in an appropriate form, which is partly provided by pseudo-scientific knowledge.The existence of pseudo-scientific information is determined by the fact that it performs important social functions in society. The existence of pseudo-scientific information by official certified scientific information and the fact, that all social groups are affected to a larger or lesser extent, show its ambivalent power and vitality. On the one part, the roots of its vitality lie in the duality of this phenomenon, where opposite things coexist in a strange way – the truth (scientifically verified propositions and speculations which are based on intuition rather than on scientifically verified facts. On the other part, it is maintained by our permanent wish to get an additional and fresher information, though not totally reliable, while seeking to know universally and better the world around us and its phenomena. While meeting this requirement, a pseudo-scientific information stimulates researchers both to enhance their attempts to

  14. Constructing Data Curation Profiles

    Directory of Open Access Journals (Sweden)

    Michael Witt

    2009-12-01

    Full Text Available This paper presents a brief literature review and then introduces the methods, design, and construction of the Data Curation Profile, an instrument that can be used to provide detailed information on particular data forms that might be curated by an academic library. These data forms are presented in the context of the related sub-disciplinary research area, and they provide the flow of the research process from which these data are generated. The profiles also represent the needs for data curation from the perspective of the data producers, using their own language. As such, they support the exploration of data curation across different research domains in real and practical terms. With the sponsorship of the Institute of Museum and Library Services, investigators from Purdue University and the University of Illinois interviewed 19 faculty subjects to identify needs for discovery, access, preservation, and reuse of their research data. For each subject, a profile was constructed that includes information about his or her general research, data forms and stages, value of data, data ingest, intellectual property, organization and description of data, tools, interoperability, impact and prestige, data management, and preservation. Each profile also presents a specific dataset supplied by the subject to serve as a concrete example. The Data Curation Profiles are being published to a public wiki for questions and discussion, and a blank template will be disseminated with guidelines for others to create and share their own profiles. This study was conducted primarily from the viewpoint of librarians interacting with faculty researchers; however, it is expected that these findings will complement a wide variety of data curation research and practice outside of librarianship and the university environment.

  15. The 12-th INS scientific computational programs

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    This issue is the collection of the paper on INS scientific computational programs. Separate abstracts were presented for 3 of the papers in this report. The remaining 5 were considered outside the subject scope of INIS. (J.P.N.)

  16. 1998-2001 Scientific Technological Report

    International Nuclear Information System (INIS)

    Gayoso C, C.; Ezpinoza Z, M.; Prado C, A.; Robles N, A.

    2002-01-01

    IPEN has elaborated the 1998-2001 Scientific-Technological Report as a result of several research and development works within the fields of production and services, and related with mining, archaeology, agriculture, biology, industry and medicine as well with tracer techniques in industry, welding quality control, speed and underground waters flows, direction, water treatment, environmental pollution, geothermy, production and calibration of radioactive sources, X-rays equipment quality control, neutron physics, neutron radiography, neutron activation analysis, water traces analysis, crystal growth and building of nuclear equipment. The 1998-2001 Scientific-Technological Report includes 148 papers divided in 8 subject matters: Nuclear and Reactor Physics, Nuclear Chemistry, Nuclear Engineering, Materials, Nuclear Safety, Protection and Radiological Safety, Nuclear Applications, and Rules and Regulation

  17. Effect of Guava in Blood Glucose and Lipid Profile in Healthy Human Subjects: A Randomized Controlled Study

    Science.gov (United States)

    Rakavi, R; Mangaraj, Manaswini

    2016-01-01

    Introduction The fruit of Psidium guajava (P.guajava) is known to contain free sugars yet the fruit juice showed hypoglycaemic effect. Hypoglycaemic activity of guava leaves has been well documented but not for guava fruit. Aim So we aimed to evaluate the effect of ripe guava (with peel and without peel) fruit supplementation on blood glucose and lipid profile in healthy human subjects. Materials and Methods Randomized Controlled study undertaken in: 1) Baseline; 2) 6 weeks supplementation phase. Forty five healthy MBBS students were included and randomly enrolled into Group A, Group B and Group C. In Baseline phase: Fasting Plasma Glucose (FPG) and serum lipid profile was done in all 3 groups. Group A were supplemented with 400g of ripe guava with peel and group B without peel, for 6 weeks. Rest 15 treated as control i.e., Group C. Result Supplementation of ripe guava fruit with peel reduced BMI as well as blood pressure (pguava pulp supplementation was not significant. Serum Total cholesterol, Triglycerides and Low Density Lipoprotein Cholesterol (LDLc) levels decreased significantly (pguava pulp without peel may have a favourable effect on lipid levels and blood sugar as well. Conclusion Guava fruit without peel is more effective in lowering blood sugar as well as serum total cholesterol, triglycerides and LDLc. It increases HDLc levels also. PMID:27790420

  18. Bibliometric analysis of Spanish scientific publications in the subject Construction & Building Technology in Web of Science database (1997-2008

    Directory of Open Access Journals (Sweden)

    Rojas-Sola, J. I.

    2010-12-01

    Full Text Available In this paper the publications from Spanish institutions listed in the journals of the Construction & Building Technology subject of Web of Science database for the period 1997- 2008 are analyzed. The number of journals in whose is published is 35 and the number of articles was 760 (Article or Review. Also a bibliometric assessment has done and we propose two new parameters: Weighted Impact Factor and Relative Impact Factor; also includes the number of citations and the number documents at the institutional level. Among the major production Institutions with greater scientific production, as expected, the Institute of Constructional Science Eduardo Torroja (CSIC, while taking into account the weighted impact factor ranks first University of Vigo. On the other hand, only two journals Cement and Concrete Materials and Materials de Construction agglutinate the 45.26% of the Spanish scientific production published in the Construction & Building Technology subject, with 172 papers each one. Regarding international cooperation, include countries such as England, Mexico, United States, Italy, Argentina and France.

    En este trabajo se analizan las publicaciones procedentes de instituciones españolas recogidas en las revistas de la categoría Construction & Building Technology de la base de datos Web of Science para el periodo 1997-2008. El número de revistas incluidas es de 35 y el número de artículos publicados ha sido de 760 (Article o Review. Se ha realizado una evaluación bibliométrica con dos nuevos parámetros: Factor de Impacto Ponderado y Factor de Impacto Relativo; asimismo se incluyen el número de citas y el número de documentos a nivel institucional. Entre los centros con una mayor producción científica destaca, como era de prever, el Instituto de Ciencias de la Construcción Eduardo Torroja (CSIC, mientras que atendiendo al Factor de Impacto Ponderado ocupa el primer lugar la Universidad de Vigo. Por otro lado, sólo dos

  19. Insulin Resistance Predicts Atherogenic Lipoprotein Profile in Nondiabetic Subjects

    Directory of Open Access Journals (Sweden)

    Flávia De C. Cartolano

    2017-01-01

    Full Text Available Background. Atherogenic diabetes is associated with an increased cardiovascular risk and mortality in diabetic individuals; however, the impact of insulin resistance (IR in lipid metabolism in preclinical stages is generally underreported. For that, we evaluated the capacity of IR to predict an atherogenic lipid subfraction profile. Methods. Complete clinical evaluation and biochemical analysis (lipid, glucose profile, LDL, and HDL subfractions and LDL phenotype and size were performed in 181 patients. The impact of IR as a predictor of atherogenic lipoproteins was tested by logistic regression analysis in raw and adjusted models. Results. HDL-C and Apo AI were significantly lower in individuals with IR. Individuals with IR had a higher percentage of small HDL particles, lower percentage in the larger ones, and reduced frequency of phenotype A (IR = 62%; non-IR = 83%. IR individuals had reduced probability to have large HDL (OR = 0.213; CI = 0.999–0.457 and had twice more chances to show increased small HDL (OR = 2.486; CI = 1.341–7.051. IR was a significant predictor of small LDL (OR = 3.075; CI = 1.341–7.051 and atherogenic phenotype (OR = 3.176; CI = 1.469–6.867. Conclusion. IR, previously DM2 diagnosis, is a strong predictor of quantitative and qualitative features of lipoproteins directly associated with an increased atherogenic risk.

  20. Chinese graduate students and U.S. scientific productivity

    Czech Academy of Sciences Publication Activity Database

    Gaulé, Patrick; Piacentini, M.

    2013-01-01

    Roč. 95, č. 2 (2013), s. 698-701 ISSN 0034-6535 Institutional support: RVO:67985998 Keywords : graduate students * Chinese immigrants * scientific output Subject RIV: AH - Economics Impact factor: 2.718, year: 2013

  1. Scientific and Technological Report 2004

    International Nuclear Information System (INIS)

    Prado Cuba, Antonio; Robles Nique, Anita; Solis Veliz, Jose; Rodriguez R, Juan

    2005-08-01

    This annual scientific and technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2004. This report includes 48 papers divided in 6 subject matters, such as: materials science, nuclear engineering, industrial and environmental applications, medical and biological applications, radiation protection and nuclear safety, and management aspects

  2. Students’ Scientific Circle of Obstetrics and Gynaecology

    Directory of Open Access Journals (Sweden)

    Ivan Polishchuk

    2017-06-01

    Full Text Available The students’ scientific circle is the kind of teaching obstetrics and gynaecology in a higher medical institution. The circle is an elective form of learning that allows the students to get deeper knowledge of a subject and to perfect themselves in the issues of diagnostics in obstetrics and gynaecology as well as to acquaint themselves with basic medical techniques. It helps identify students who are capable of scientific research and allows the students to improve their ability to analytical perception of professional information, the ability to present it to the audience, ask and answer the questions publicly. The article presents the results of practical and research activities of obstetric and gynaecologic section of the students’ scientific circle of Ivano-Frankivsk National Medical University.

  3. Open-Access Mega-Journals: A Bibliometric Profile.

    Science.gov (United States)

    Wakeling, Simon; Willett, Peter; Creaser, Claire; Fry, Jenny; Pinfield, Stephen; Spezi, Valérie

    2016-01-01

    In this paper we present the first comprehensive bibliometric analysis of eleven open-access mega-journals (OAMJs). OAMJs are a relatively recent phenomenon, and have been characterised as having four key characteristics: large size; broad disciplinary scope; a Gold-OA business model; and a peer-review policy that seeks to determine only the scientific soundness of the research rather than evaluate the novelty or significance of the work. Our investigation focuses on four key modes of analysis: journal outputs (the number of articles published and changes in output over time); OAMJ author characteristics (nationalities and institutional affiliations); subject areas (the disciplinary scope of OAMJs, and variations in sub-disciplinary output); and citation profiles (the citation distributions of each OAMJ, and the impact of citing journals). We found that while the total output of the eleven mega-journals grew by 14.9% between 2014 and 2015, this growth is largely attributable to the increased output of Scientific Reports and Medicine. We also found substantial variation in the geographical distribution of authors. Several journals have a relatively high proportion of Chinese authors, and we suggest this may be linked to these journals' high Journal Impact Factors (JIFs). The mega-journals were also found to vary in subject scope, with several journals publishing disproportionately high numbers of articles in certain sub-disciplines. Our citation analsysis offers support for Björk & Catani's suggestion that OAMJs's citation distributions can be similar to those of traditional journals, while noting considerable variation in citation rates across the eleven titles. We conclude that while the OAMJ term is useful as a means of grouping journals which share a set of key characteristics, there is no such thing as a "typical" mega-journal, and we suggest several areas for additional research that might help us better understand the current and future role of OAMJs in

  4. SCHOOL LINGUISTIC CREATIVITY BASED ON SCIENTIFIC GEOGRAPHICAL TEXTS

    Directory of Open Access Journals (Sweden)

    VIORICA BLÎNDĂ

    2012-01-01

    Full Text Available The analysis and observation of the natural environment and of the social and economic one, observing phenomena, objects, beings, and geographical events are at the basis of producing geographical scientific texts. The symbols of iconotexts and cartotexts are another source of inspiration for linguistic interpretation. The linguistic creations that we selected for our study are the scientific analysis, the commentary, the characterization, the parallel, the synthesis, epitomizing and abstracting, the scientific communication, the essay, and the scientific description. The representations on maps, photos, graphics and profiles are translated into verbal or written expression in order to render geographical scientific information from diagrams and images through diverse discursive procedures. Through school linguistic creations, teachers develop their students’ observation spirit, in a written and oral form, their geographical thinking through metaphors, they develop and stimulate their students’ imagination and fantasy, their cognitive, reflexive and affective sensitivity, their abilities to express themselves, to present and argument in a scientific way according to different criteria (sufficiency, demonstrative reasoning, lineal reasoning, pros and cons, giving examples, inferential deduction through using truth tables, etc.. Trough description, students give names and define geographical objects and beings (plants, animals, and people according to their form and aspect, they explain toponyms and appellatives, they classify and make hierarchies, they define their identity through processes of differentiation, emblematizing, personification, location in time and space.

  5. On systematization of anti-corruption work in the Russian Federation subjects under the modern conditions

    Directory of Open Access Journals (Sweden)

    Igor I. Bikeev

    2015-12-01

    Full Text Available Objective scientific and legal evaluation of new corruption counteraction tools in the Russian Federation subjects stipulated by the Decree of the President of the Russian Federation No. 364 of 15 July 2015 and proposals for their use and improvement. Methods dialectical systemic and synergistic methods as general scientific methods of cognition formaljuridical analysis of documents expert assessments linguistic as private scientific methods of cognition. Results the authors assess the legal regulation and organization of activity of commissions for the coordination of corruption counteraction in the Russian Federation subjects and their authorities on corruption and other offences prevention and propose measures for their improvement. Scientific novelty for the first time after the adoption of the Decree of the President of the Russian Federation No. 364 of 15 July 2015 the main directions to improve the regional subjects of corruption counteraction are defined. Practical significance the organizational and legal measures are proposed for improving and ensuring the activities of regional subjects of corruption counteraction.

  6. Improving Scientific Voice in the Science Communication Center at UT Knoxville

    Science.gov (United States)

    Hirst, Russel

    2013-01-01

    Many science students believe that scientific writing is most impressive (and most professionally acceptable) when impersonal, dense, complex, and packed with jargon. In particular, they have the idea that legitimate scientific writing must suppress the subjectivity of the human voice. But science students can mature into excellent writers whose…

  7. [IMPACT OF DIETARY FATTY ACIDS ON LIPID PROFILE, INSULIN SENSITIVITY AND FUNCTIONALITY OF PANCREATIC β CELLS IN TYPE 2 DIABETIC SUBJECTS].

    Science.gov (United States)

    Sambra Vásquez, Verónica; Rojas Moncada, Pamela; Basfi-Fer, Karen; Valencia, Alejandra; Codoceo, Juana; Inostroza, Jorge; Carrasco, Fernando; Ruz Ortiz, Manuel

    2015-09-01

    the quality of fats could influence the metabolic control of patients with Type 2 Diabetes Mellitus (DM2). to determine the relationship between intake and quality of dietary fatty acids to lipid profile, metabolic control, functionality of pancreatic cells and insulin sensivity in subjects with DM2. we studied 54 subjects with DM2, anthropometric measurements were performed, body composition and dietary lipid intake, saturated fatty acids (SFA), trans, monounsaturated, polyunsaturated, omega 3, omega 6 and dietary cholesterol. Laboratory parameters related to their metabolic control were determined (fasting blood glucose, glycated hemoglobin, and lipid profile). The insulin secretion and insulin sensitivity was determined with the insulin-modified intravenous glucose tolerance test according to the Bergman's minimal model. 28 men and 26 women were studied (BMI of 29.5 ± 3.7 kg/m2; age 55.6 ± 6.8 y.), 48% had LDL-C 40 mg/dL and 7.4% of women c-HDL > 50 mg/dL. 32% consumed > 10% of AGS and > 300 mg/day of dietary cholesterol. The SFA intake and percentage of calories from fat (G%) were significantly associated with insulin resistance and fasting plasma glucose concentration. The G% predicted 84% variability on c-VLDL. in patients with DM2 a greater intake of fat and saturated fatty acids it associated with greater fasting glycemia and insulin resistance. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  8. Sagittal Thoracic and Lumbar Spine Profiles in Upright Standing and Lying Prone Positions Among Healthy Subjects: Influence of Various Biometric Features.

    Science.gov (United States)

    Salem, Walid; Coomans, Ysaline; Brismée, Jean-Michel; Klein, Paul; Sobczak, Stéphane; Dugailly, Pierre-Michel

    2015-08-01

    A prospective study was performed on the assessment of both thoracic and lumbar spine sagittal profiles (from C7 to S1). To propose a new noninvasive method for measuring the spine curvatures in standing and lying prone positions and to analyze their relationship with various biometric characteristics. Modifications of spine curvatures (i.e. lordosis or kyphosis) are of importance in the development of spinal disorders. Studies have emphasized the development of new devices to measure the spine sagittal profiles using a noninvasive and low-cost method. To date, it has not been applied for analyzing both lumbar and thoracic alterations for various positioning. Seventy-five healthy subjects (mean 22.6 ± 4.3 yr) were recruited to participate in this study. Thoracic and lumbar sagittal profiles were assessed in standing and lying prone positions using a 3D digitizer. In addition, several biometric data were collected including maximal trunk isometric strength for flexion and extension movement. Statistical analysis consisted in data comparisons of spine profiles and a multivariate analysis including biometric features, to classify individuals considering low within- and high between-variability. Kyphosis and lordosis angles decreased significantly from standing to lying prone position by an average of 13.4° and 16.6°, respectively. Multivariate analysis showed a sample clustering of 3 homogenous subgroups. The first group displayed larger lordosis and flexibility, and had low data values for height, weight, and strength. The second group had lower values than the overall trend of the whole sample, whereas the third group had larger score values for the torques, height, weight, waist, body mass index, and kyphosis angle but a reduced flexibility. The present results demonstrate a significant effect of the positioning on both thoracic and lumbar spine sagittal profiles and highlight the use of cluster analysis to categorize subgroups after biometric characteristics

  9. Use of scientific information database to pursue the policy in science and industry

    International Nuclear Information System (INIS)

    Vajkhet, I.

    1984-01-01

    Analysis methods of scientific and technical information are presented to determine regularities in scientific and technical development. As a rule, the studies are carried out using data base of patent literature. Three methods of are considered. The first one - analysis of data flow, when trends in technique, degree of the technique monopolyzation and its urgency are evaluated. The second one - lexical analysis, consisting in recording new terms and deviations in the number of terms with time. The third one - analysis of quatation networks, which leads to the establisment of author and subject groups, characterizing scientific and technical activity of the object observed, of a firm or subject area for instance

  10. The ruins of neo-liberalism and the construction of a new (scientific) subjectivity

    Science.gov (United States)

    Lather, Patti

    2012-12-01

    Given my long-time interests in neoliberalism and questions of subjectivity, I am pleased to respond to Jesse Bazzul's paper, "Neoliberal Ideology, global capitalism, and science education: Engaging the question of subjectivity." In what follows, I first summarize what I see as Bazzul's contributions to pushing science education in `post' directions. I next introduce the concept of "post-neoliberalism" as a tool in this endeavor. Finally, I address what all of this might have to do with subjectivity in the context of science education. I speak as a much-involved veteran of a version of the science wars fought out in education research for the last decade (NRC 2002). My interest is to use this "battle" to think politics and science anew toward an engaged social science, without certainty, rethinking subjectivity, the unconscious and bodies where I ask "what kind of science for what kind of politics?"

  11. Science and society: The benefits of scientific collaboration

    CERN Multimedia

    2003-01-01

    The guest speaker at the next Science and Society symposium is no stranger to CERN. He is, in fact, Sir Chris Llewellyn Smith, Director General of CERN from 1994 to 1998. His topic is one with which he is particularly familiar, having "lived" it throughout his time at CERN: international scientific collaboration and its advantages. International scientific collaboration is essential in a wide range of areas and for a large number of reasons: scientific problems have no frontiers; certain subjects are so complex that they require the expertise of numerous countries; certain types of research, such as that carried out at CERN, cannot be pursued by one nation on its own. However, scientific collaboration is not only beneficial to science itself. This is the point Chris Llewellyn Smith intends to demonstrate in his address. Scientific collaboration can help to build bridges between societies and act as a spur to the development of certain countries. It can even help to diminish conflicts in certain cases. The his...

  12. Scientific and Technological Report 2006

    International Nuclear Information System (INIS)

    Prado Cuba, Antonio; Robles Nique, Anita; Solis Veliz, Jose; Osores Rebaza, Jose

    2007-08-01

    This annual scientific and technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2006. This report includes 54 papers divided in 7 subject matters, such as: physics and chemistry, materials science, nuclear engineering, industrial and environmental applications, medical and biological applications, radiation protection and nuclear safety, and management aspects. (APC)

  13. Scientific and Technological Report 2005

    International Nuclear Information System (INIS)

    Prado Cuba, Antonio; Robles Nique, Anita; Rodriguez R, Juan; Solis Veliz, Jose

    2006-07-01

    This annual scientific and technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2005. This report includes 38 papers divided in 7 subject matters, such as: physics and chemistry, materials science, nuclear engineering, industrial and environmental applications, medical and biological applications, radiation protection and nuclear safety, and management aspects

  14. Deep-sea disposal: Scientific bases to control pollution

    International Nuclear Information System (INIS)

    Hagen, A.

    1986-01-01

    The IAEA's responsibilities are to define high-level radioactive waste that is prohibited from being dumped and make recommendations for the dumping of other radioactive waste. The IAEA had set up a series of scientific meetings and also had requested the scientific group GESAMP to advise it on suitable models for calculating concentrations of radionuclides above which sea-dumping would be prohibited. The NEA/OECD had established in 1981 a Coordinated Research and Environmental Surveillance Programme CRESP relevant to sea disposal for an initial period of 4 years. This article presents improving the scientific basis, summary of major issues and CRESP review covering five subject areas: model development, physical oceanography, geochemistry, biology, and radiological surveillance

  15. Influence of Peripheral Artery Disease and Statin Therapy on Apolipoprotein Profiles

    Directory of Open Access Journals (Sweden)

    Andrew W. Gardner

    2013-01-01

    Full Text Available Apolipoprotein B is a stronger predictor of myocardial infarction than LDL cholesterol, and it is inversely related to physical activity and modifiable with exercise training. As such, apolipoprotein measures may be of particular relevance for subjects with PAD and claudication. We compared plasma apolipoprotein profiles in 29 subjects with peripheral artery disease (PAD and intermittent claudication and in 39 control subjects. Furthermore, we compared the plasma apolipoprotein profiles of subjects with PAD either treated (n=17 or untreated (n=12 with statin medications. For the apolipoprotein subparticle analyses, subjects with PAD had higher age-adjusted Lp-B:C (P<0.05 and lower values of Lp-A-I:A-II (P<0.05 than controls. The PAD group taking statins had lower age-adjusted values for apoB (P<0.05, Lp-A-II:B:C:D:E (P<0.05, Lp-B:E + Lp-B:C:E (P<0.05, Lp-B:C (P<0.05, and Lp-A-I (P<0.05 than the untreated PAD group. Subjects with PAD have impaired apolipoprotein profiles than controls, characterized by Lp-B:C and Lp-A-I:A-II. Furthermore, subjects with PAD on statin medications have a more favorable risk profile, particularly noted in multiple apolipoprotein subparticles. The efficacy of statin therapy to improve cardiovascular risk appears more evident in the apolipoprotein sub-particle profile than in the more traditional lipid profile of subjects with PAD and claudication. This trial is registered with ClinicalTrials.gov NCT00618670.

  16. Comparative gut microbiota and resistome profiling of intensive care patients receiving selective digestive tract decontamination and healthy subjects.

    Science.gov (United States)

    Buelow, Elena; Bello González, Teresita D J; Fuentes, Susana; de Steenhuijsen Piters, Wouter A A; Lahti, Leo; Bayjanov, Jumamurat R; Majoor, Eline A M; Braat, Johanna C; van Mourik, Maaike S M; Oostdijk, Evelien A N; Willems, Rob J L; Bonten, Marc J M; van Passel, Mark W J; Smidt, Hauke; van Schaik, Willem

    2017-08-14

    The gut microbiota is a reservoir of opportunistic pathogens that can cause life-threatening infections in critically ill patients during their stay in an intensive care unit (ICU). To suppress gut colonization with opportunistic pathogens, a prophylactic antibiotic regimen, termed "selective decontamination of the digestive tract" (SDD), is used in some countries where it improves clinical outcome in ICU patients. Yet, the impact of ICU hospitalization and SDD on the gut microbiota remains largely unknown. Here, we characterize the composition of the gut microbiota and its antimicrobial resistance genes ("the resistome") of ICU patients during SDD and of healthy subjects. From ten patients that were acutely admitted to the ICU, 30 fecal samples were collected during ICU stay. Additionally, feces were collected from five of these patients after transfer to a medium-care ward and cessation of SDD. Feces from ten healthy subjects were collected twice, with a 1-year interval. Gut microbiota and resistome composition were determined using 16S rRNA gene phylogenetic profiling and nanolitre-scale quantitative PCRs. The microbiota of the ICU patients differed from the microbiota of healthy subjects and was characterized by lower microbial diversity, decreased levels of Escherichia coli and of anaerobic Gram-positive, butyrate-producing bacteria of the Clostridium clusters IV and XIVa, and an increased abundance of Bacteroidetes and enterococci. Four resistance genes (aac(6')-Ii, ermC, qacA, tetQ), providing resistance to aminoglycosides, macrolides, disinfectants, and tetracyclines, respectively, were significantly more abundant among ICU patients than in healthy subjects, while a chloramphenicol resistance gene (catA) and a tetracycline resistance gene (tetW) were more abundant in healthy subjects. The gut microbiota of SDD-treated ICU patients deviated strongly from the gut microbiota of healthy subjects. The negative effects on the resistome were limited to selection

  17. The Ruins of Neo-Liberalism and the Construction of a New (Scientific) Subjectivity

    Science.gov (United States)

    Lather, Patti

    2012-01-01

    Given my long-time interests in neoliberalism and questions of subjectivity, I am pleased to respond to Jesse Bazzul's paper, "Neoliberal Ideology, global capitalism, and science education: Engaging the question of subjectivity." In what follows, I first summarize what I see as Bazzul's contributions to pushing science education in "post"…

  18. Representing scientific knowledge the role of uncertainty

    CERN Document Server

    Chen, Chaomei

    2017-01-01

    This book is written for anyone who is interested in how a field of research evolves and the fundamental role of understanding uncertainties involved in different levels of analysis, ranging from macroscopic views to meso- and microscopic ones. We introduce a series of computational and visual analytic techniques, from research areas such as text mining, deep learning, information visualization and science mapping, such that readers can apply these tools to the study of a subject matter of their choice. In addition, we set the diverse set of methods in an integrative context, that draws upon insights from philosophical, sociological, and evolutionary theories of what drives the advances of science, such that the readers of the book can guide their own research with their enriched theoretical foundations. Scientific knowledge is complex. A subject matter is typically built on its own set of concepts, theories, methodologies and findings, discovered by generations of researchers and practitioners. Scientific ...

  19. Lexical Features of Scientific Discourse

    Directory of Open Access Journals (Sweden)

    Tatjana Rusko

    2014-06-01

    Full Text Available Currently, a lot of emphasis is placed of the ability of a person to successfully communicate in any sphere of activity, which along with upbringing and education is among the factors that determine a person’s culture. In the context of rapid scientific and technological progress, it is vital to constantly exchange relevant infor- mation. The effectiveness of this process relies not only on the proficient knowledge of the subject and the ability to make grammatically correct sentences, but to a large extent on the level of competence in scientific language. The present article attempts to consider the interaction of discourse and vocabulary, different types of cognitive phenomena responsible for the use of a language in real time and related to the language as a means of storing and organising information. Analysing and classifying some key elements of a scientific discourse lexicon contributes to the development of certain provisions of lexicology, functional stylistics, cognitive linguistics and terminology. The results of the analysis may be advantageous both to linguistics and teaching the language for specific purposes.

  20. Confounding factors and genetic polymorphism in the evaluation of individual steroid profiling

    Science.gov (United States)

    Kuuranne, Tiia; Saugy, Martial; Baume, Norbert

    2014-01-01

    In the fight against doping, steroid profiling is a powerful tool to detect drug misuse with endogenous anabolic androgenic steroids. To establish sensitive and reliable models, the factors influencing profiling should be recognised. We performed an extensive literature review of the multiple factors that could influence the quantitative levels and ratios of endogenous steroids in urine matrix. For a comprehensive and scientific evaluation of the urinary steroid profile, it is necessary to define the target analytes as well as testosterone metabolism. The two main confounding factors, that is, endogenous and exogenous factors, are detailed to show the complex process of quantifying the steroid profile within WADA-accredited laboratories. Technical aspects are also discussed as they could have a significant impact on the steroid profile, and thus the steroid module of the athlete biological passport (ABP). The different factors impacting the major components of the steroid profile must be understood to ensure scientifically sound interpretation through the Bayesian model of the ABP. Not only should the statistical data be considered but also the experts in the field must be consulted for successful implementation of the steroidal module. PMID:24764553

  1. SCIENTIFIC AND METHODICAL ASPECTS OF FORMATION OF SUBJECT CONTENT OF TRAINING COURSESFOR INVERSE PROBLEMS FOR DIFFERENTIAL EQUATIONS

    Directory of Open Access Journals (Sweden)

    В С Корнилов

    2016-12-01

    Full Text Available The article presents scientific and methodical aspects of forming the content of education inverse problems for differential equations for students of higher educational institutions of physical, mathematical and natural science training areas. The goals are formulated and the principles of training are the content of learning inverse problems for differential equations. Attention is drawn to the particular issues of teaching courses inverse problems. Describes the classification criteria and target modules that play the role of tools to create and analyze the model and curriculum, forming learning content inverse problems for differential equations. The content classification features and target modules. Formulate conclusions that learning the inverse problems for differential equations has scientific, educational and humanitarian potential of students and as a result of this training they gain the fundamental knowledge in the applied and computational mathematics, and also develop scientific worldview, applied, environmental, information thinking.

  2. The application of subjective job task analysis techniques in physically demanding occupations: evidence for the presence of self-serving bias.

    Science.gov (United States)

    Lee-Bates, Benjamin; Billing, Daniel C; Caputi, Peter; Carstairs, Greg L; Linnane, Denise; Middleton, Kane

    2017-09-01

    The aim of this study was to determine if perceptions of physically demanding job tasks are biased by employee demographics and employment profile characteristics including: age, sex, experience, length of tenure, rank and if they completed or supervised a task. Surveys were administered to 427 Royal Australian Navy personnel who characterised 33 tasks in terms of physical effort, importance, frequency, duration and vertical/horizontal distance travelled. Results showed no evidence of bias resulting from participant characteristics, however participants who were actively involved in both task participation and supervision rated these tasks as more important than those involved only in the supervision of that task. This may indicate self-serving bias in which participants that are more actively involved in a task had an inflated perception of that task's importance. These results have important implications for the conduct of job task analyses, especially the use of subjective methodologies in the development of scientifically defensible physical employment standards. Practitioner Summary: To examine the presence of systematic bias in subjective job task analysis methodologies, a survey was conducted on a sample of Royal Australian Navy personnel. The relationship between job task descriptions and participant's demographic and job profile characteristics revealed the presence of self-serving bias affecting perceptions of task importance.

  3. Pre-Service Elementary Teachers’ Scientific Literacy and Self-Efficacy in Teaching Science

    Directory of Open Access Journals (Sweden)

    Adam Al Sultan

    2018-02-01

    Full Text Available Many educators and educational institutions worldwide have agreed that the main goal of science education is to produce a scientifically literate community. Science teachers are key to the achievement of scientific literacy at all levels of education because of the essential role they play in preparing scientifically literate individuals. Studies show that pre-service elementary teachers need to build more confidence in teaching science and scientific literacy during their teacher education programs in order for them to successfully teach science knowledge to their students. Therefore, the purpose of this study is threefold. First, pre-service elementary teachers' scientific literacy levels were examined. Second, pre-service teachers' self-efficacy beliefs were measured by distinguishing between their personal and subject-specific self-efficacy beliefs. Third, the extent to which pre-service elementary teachers' scientific literacy levels and self-efficacy levels are related was investigated. Participants were 49 pre-service elementary teachers registered in two science methods courses (introductory and advanced at a mid-sized university in the United States. Quantitative data were collected using the Test of Basic Scientific Literacy, the Science Teaching Efficacy Belief Instrument-Preservice, and Beliefs about Teaching. Results showed that participants had a satisfactory level of scientific literacy. However, pre-service teachers had borderline scores on the Nature of Science scale. Regarding self-efficacy, findings showed that both groups had the highest self-efficacy in teaching biology and the lowest in teaching physics. Participants in the advanced science methods course exhibited a moderate preexisting positive relationship between scientific literacy and subject-specific self-efficacy in teaching science.

  4. Claim Assessment Profile: A Method for Capturing Healthcare Evidence in the Scientific Evaluation and Review of Claims in Health Care (SEaRCH).

    Science.gov (United States)

    Hilton, Lara; Jonas, Wayne B

    2017-02-01

    Grounding health claims in an evidence base is essential for determining safety and effectiveness. However, it is not appropriate to evaluate all healthcare claims with the same methods. "Gold standard" randomized controlled trials may skip over important qualitative and observational data about use, benefits, side effects, and preferences, issues especially salient in research on complementary and integrative health (CIH) practices. This gap has prompted a move toward studying treatments in their naturalistic settings. In the 1990s, a program initiated under the National Institutes of Health was designed to provide an outreach to CIH practices for assessing the feasibility of conducting retrospective or prospective evaluations. The Claim Assessment Profile further develops this approach, within the framework of Samueli Institute's Scientific Evaluation and Review of Claims in Health Care (SEaRCH) method. The goals of a Claim Assessment Profile are to clarify the elements that constitute a practice, define key outcomes, and create an explanatory model of these impacts. The main objective is to determine readiness and capacity of a practice to engage in evaluation of effectiveness. This approach is informed by a variety of rapid assessment and stakeholder-driven methods. Site visits, structured qualitative interviews, surveys, and observational data on implementation provide descriptive data about the practice. Logic modeling defines inputs, processes, and outcome variables; Path modeling defines an analytic map to explore. The Claim Assessment Profile is a rapid assessment of the evaluability of a healthcare practice. The method was developed for use on CIH practices but has also been applied in resilience research and may be applied beyond the healthcare sector. Findings are meant to provide sufficient data to improve decision-making for stakeholders. This method provides an important first step for moving existing promising yet untested practices into

  5. Characteristics of scientific web publications

    DEFF Research Database (Denmark)

    Thorlund Jepsen, Erik; Seiden, Piet; Ingwersen, Peter Emil Rerup

    2004-01-01

    were generated based on specifically selected domain topics that are searched for in three publicly accessible search engines (Google, AllTheWeb, and AltaVista). A sample of the retrieved hits was analyzed with regard to how various publication attributes correlated with the scientific quality...... of the content and whether this information could be employed to harvest, filter, and rank Web publications. The attributes analyzed were inlinks, outlinks, bibliographic references, file format, language, search engine overlap, structural position (according to site structure), and the occurrence of various...... types of metadata. As could be expected, the ranked output differs between the three search engines. Apparently, this is caused by differences in ranking algorithms rather than the databases themselves. In fact, because scientific Web content in this subject domain receives few inlinks, both Alta...

  6. 5th International Conference on High Performance Scientific Computing

    CERN Document Server

    Hoang, Xuan; Rannacher, Rolf; Schlöder, Johannes

    2014-01-01

    This proceedings volume gathers a selection of papers presented at the Fifth International Conference on High Performance Scientific Computing, which took place in Hanoi on March 5-9, 2012. The conference was organized by the Institute of Mathematics of the Vietnam Academy of Science and Technology (VAST), the Interdisciplinary Center for Scientific Computing (IWR) of Heidelberg University, Ho Chi Minh City University of Technology, and the Vietnam Institute for Advanced Study in Mathematics. The contributions cover the broad interdisciplinary spectrum of scientific computing and present recent advances in theory, development of methods, and practical applications. Subjects covered include mathematical modeling; numerical simulation; methods for optimization and control; parallel computing; software development; and applications of scientific computing in physics, mechanics and biomechanics, material science, hydrology, chemistry, biology, biotechnology, medicine, sports, psychology, transport, logistics, com...

  7. 3rd International Conference on High Performance Scientific Computing

    CERN Document Server

    Kostina, Ekaterina; Phu, Hoang; Rannacher, Rolf

    2008-01-01

    This proceedings volume contains a selection of papers presented at the Third International Conference on High Performance Scientific Computing held at the Hanoi Institute of Mathematics, Vietnamese Academy of Science and Technology (VAST), March 6-10, 2006. The conference has been organized by the Hanoi Institute of Mathematics, Interdisciplinary Center for Scientific Computing (IWR), Heidelberg, and its International PhD Program ``Complex Processes: Modeling, Simulation and Optimization'', and Ho Chi Minh City University of Technology. The contributions cover the broad interdisciplinary spectrum of scientific computing and present recent advances in theory, development of methods, and applications in practice. Subjects covered are mathematical modelling, numerical simulation, methods for optimization and control, parallel computing, software development, applications of scientific computing in physics, chemistry, biology and mechanics, environmental and hydrology problems, transport, logistics and site loca...

  8. 6th International Conference on High Performance Scientific Computing

    CERN Document Server

    Phu, Hoang; Rannacher, Rolf; Schlöder, Johannes

    2017-01-01

    This proceedings volume highlights a selection of papers presented at the Sixth International Conference on High Performance Scientific Computing, which took place in Hanoi, Vietnam on March 16-20, 2015. The conference was jointly organized by the Heidelberg Institute of Theoretical Studies (HITS), the Institute of Mathematics of the Vietnam Academy of Science and Technology (VAST), the Interdisciplinary Center for Scientific Computing (IWR) at Heidelberg University, and the Vietnam Institute for Advanced Study in Mathematics, Ministry of Education The contributions cover a broad, interdisciplinary spectrum of scientific computing and showcase recent advances in theory, methods, and practical applications. Subjects covered numerical simulation, methods for optimization and control, parallel computing, and software development, as well as the applications of scientific computing in physics, mechanics, biomechanics and robotics, material science, hydrology, biotechnology, medicine, transport, scheduling, and in...

  9. SPECIEUROPE: The European data base for PM source profiles

    OpenAIRE

    PERNIGOTTI DENISE; BELIS CLAUDIO; SPANO' LUCA

    2015-01-01

    A database of atmospheric particulate matter emission source profiles in Europe (SPECIEUROPE) was developed by the Joint Research Center in the framework of the Forum for air quality modeling in Europe (FAIRMODE, Working Group 3). It contains the chemical composition of particulate matter (PM) emission sources reported in the scientific literature and reports drafted by competent authorities. The first release of SPECIEUROPE consists of 151 measured profiles (original), 13 composite (merging ...

  10. The profile of the Montessori assistant: historical paths and new education projects

    Directory of Open Access Journals (Sweden)

    Barbara De Serio

    2016-07-01

    Full Text Available This paper looks at the professional profile of the Montessori-trained teacher, as educated at the college devised by Maria Montessori and founded in the 1950s by one of her closest pupils, Adele Costa Gnocchi. The Montessori assistant was a professional figure specially trained to aid the birth process and the “mental” needs of the protagonists involved, referring specifically to the child. In this respect, the paper also looks at the subject of education from birth, starting with Montessori’s earliest ideas on new-born children and their creative capabilities. The purpose is to recover the scientific foundations on which the pedagogical practices usually applied by childhood services are based, with the awareness that these consolidated practices need strengthening and a scientific foundation – including on an historical level – in order to contribute to qualifying services for early childhood. Through specific methodological qualification, above all with regard to Montessori’s methods, as well as by placing more valid historical importance on the paths they began, early childhood services may even be able to move in the direction of possible institutionalised training.

  11. Four stages of a scientific discipline; four types of scientist.

    Science.gov (United States)

    Shneider, Alexander M

    2009-05-01

    In this article I propose the classification of the evolutionary stages that a scientific discipline evolves through and the type of scientists that are the most productive at each stage. I believe that each scientific discipline evolves sequentially through four stages. Scientists at stage one introduce new objects and phenomena as subject matter for a new scientific discipline. To do this they have to introduce a new language adequately describing the subject matter. At stage two, scientists develop a toolbox of methods and techniques for the new discipline. Owing to this advancement in methodology, the spectrum of objects and phenomena that fall into the realm of the new science are further understood at this stage. Most of the specific knowledge is generated at the third stage, at which the highest number of original research publications is generated. The majority of third-stage investigation is based on the initial application of new research methods to objects and/or phenomena. The purpose of the fourth stage is to maintain and pass on scientific knowledge generated during the first three stages. Groundbreaking new discoveries are not made at this stage. However, new ways to present scientific information are generated, and crucial revisions are often made of the role of the discipline within the constantly evolving scientific environment. The very nature of each stage determines the optimal psychological type and modus operandi of the scientist operating within it. Thus, it is not only the talent and devotion of scientists that determines whether they are capable of contributing substantially but, rather, whether they have the 'right type' of talent for the chosen scientific discipline at that time. Understanding the four different evolutionary stages of a scientific discipline might be instrumental for many scientists in optimizing their career path, in addition to being useful in assembling scientific teams, precluding conflicts and maximizing

  12. The next scientific revolution.

    Science.gov (United States)

    Hey, Tony

    2010-11-01

    For decades, computer scientists have tried to teach computers to think like human experts. Until recently, most of those efforts have failed to come close to generating the creative insights and solutions that seem to come naturally to the best researchers, doctors, and engineers. But now, Tony Hey, a VP of Microsoft Research, says we're witnessing the dawn of a new generation of powerful computer tools that can "mash up" vast quantities of data from many sources, analyze them, and help produce revolutionary scientific discoveries. Hey and his colleagues call this new method of scientific exploration "machine learning." At Microsoft, a team has already used it to innovate a method of predicting with impressive accuracy whether a patient with congestive heart failure who is released from the hospital will be readmitted within 30 days. It was developed by directing a computer program to pore through hundreds of thousands of data points on 300,000 patients and "learn" the profiles of patients most likely to be rehospitalized. The economic impact of this prediction tool could be huge: If a hospital understands the likelihood that a patient will "bounce back," it can design programs to keep him stable and save thousands of dollars in health care costs. Similar efforts to uncover important correlations that could lead to scientific breakthroughs are under way in oceanography, conservation, and AIDS research. And in business, deep data exploration has the potential to unearth critical insights about customers, supply chains, advertising effectiveness, and more.

  13. Scientific and Technological Report 2009

    International Nuclear Information System (INIS)

    Prado Cuba, Antonio; Santiago Contreras, Julio; Lopez Milla, Alcides; Ramos Trujillo, Bertha

    2010-11-01

    This annual scientific and technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2009. This report includes 46 papers divided in 7 subject matters, such as: physics and chemistry, materials science, nuclear engineering, mining industrial and environmental applications, medical and biological applications, radiation protection and nuclear safety, and management aspects. It also includes annexes. (APC)

  14. Scientific and Technological Report 2008

    International Nuclear Information System (INIS)

    Prado Cuba, A.; Santiago Contreras, J.; Rojas Tapia, J.; Ramos Trujillo, B.; Vela Mora, M.; Castro Gamero, E.

    2010-04-01

    This annual scientific and technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2008. This report includes 60 papers divided in 7 subject matters, such as: physics and chemistry, materials science, nuclear engineering, mining industrial and environmental applications, medical and biological applications, radiation protection and nuclear safety, and management aspects. It also includes annexes. (APC)

  15. Commercial viability of CNS drugs: balancing the risk/reward profile.

    Science.gov (United States)

    Johnson, Ginger S

    2014-01-01

    CNS has historically been a formidable therapeutic area in which to innovate owing to biological (e.g., complex neurobiology, difficulty reaching the target), as well as clinical (e.g., subjective clinical endpoints, high placebo response, lack of biomarkers) challenges. In the current market where many of the larger diseases are dominated by a generic standard of care, commercial challenges now make the triple threat of scientific-clinical-commercial risk too much for many players to tackle. However, opportunities do exist for smaller biotech companies to concentrate on narrowly focused patient populations associated with high unmet need for which risk can be tightly defined. In CNS, there are two major areas to balance the risk/reward profile and create commercially viable opportunities: To realize value, all companies (start-ups and big players) must define, measure and quantify clear and meaningful value to all stakeholders: physicians, patients, caregivers and payers. © 2013.

  16. Conceiving, Writing and Publishing a Scientific Paper

    Directory of Open Access Journals (Sweden)

    Marta Christina Suciu

    2018-02-01

    Full Text Available I consider that the second edition of the book “Conceiving, Writing and Publishing a Scientific Paper. An approach in the context of economic research” is a work of high scientific standing, excellently documented, addressed to knowledgeable readers but also to the new generations of PhD students and researchers interested in attaining the highest academic and scientific performances in the field of Economics. From my point of view, both editions of the book are highly useful for the academic environment. I especially appreciate the authors’ efforts to improve and expand the second edition. This fact is due to the changes occurred in the evolution of scientometric indicators, to the feedback received from readers, but also as the result of the desire to include multiple networks and platforms that take into account professional and institutional profiles, such as to facilitate the researchers’ dissemination of their results obtained in the scientific research activity. The authors benefit on an unanimous recognition and are highly appreciated., fact proven for example by the ten existing reviews of the book’s first edition, published in journals indexed in Web of Science, Scopus and other international databases. I am mostly impressed by the authors’ permanent concern to improve their book’s scientific content. The first edition was awarded the distinction “The Best Book in the Field of Economics” published in 2016 in Romania by the Association of Romanian Economic Faculties, but also by The Association of Cultural-Educational Cooperation from Suceava (ACCES prize in 2016

  17. The Need for More Scientific Approaches to Science Communication

    Science.gov (United States)

    Sadri, S.

    2015-12-01

    Two possible goals for public science communication are: a) improving the public's in-depth understanding of the scientific subject; and b) fostering the public's belief that scientific efforts make a better world. Although (a) is often a natural target when scientists try to communicate their subject, the importance of (b) is underscored by the NSF, who investigated the "cultural authority of science" to understand science's role in policymaking. Surveys consistently find that there is a huge divergence between "knowledge" and "admiration" of science in society because science literacy has very little to do with public perception of science. However, even if both goals could be achieved, it doesn't necessarily mean that the general public will act on scientific advice. Different parts of society have different criteria for reaching judgments about how to act in their best interests. This makes the study of science communication important when controversies arise requiring public engagement. Climate change, sustainability, and water crises are only a few examples of such controversial subjects. Science communication can be designed carefully to sponsor dialogue and participation, to overcome perceptual obstacles, and to engage with stakeholders and the wider public. This study reviews work in social science that tries to answer: When is science communication necessary? What is involved in science communication? What is the role of media in effective science communication? It also reviews common recommendations for improved public engagement by scientists and science organizations. As part of this effort, I will present some portions of my science films. I will conclude with suggestions on what scientific institutions can focus on to build trust, relationships, and participation across segments of the public. Keywords: informal learning, popular science, climate change, water crisis, science communication, science films, science policy.

  18. Standard distribution for unclassified scientific and technical reports: instructions and category scope notes

    International Nuclear Information System (INIS)

    1980-12-01

    The US Department of Energy Technical Information Center (DOE/TIC) uses a subject category scheme for classifying and distributing DOE-originated or -sponsored unclassified scientific and technical reports. This document contains the subject category scope notes used for these purposes. Originators of DOE or DOE-sponsored scientific and technical reports are urged to adhere to the instructions contained this publication. A limited number of copies of the unabridged version (addresses included) are available to Department of Energy offices and their contractors as DOE/TIC-4500(Rev.69)(Unabridged)

  19. The Scientific Mind: Ever Searching, Never Certain

    Directory of Open Access Journals (Sweden)

    Leonard N. Ezegbunam

    2008-02-01

    Full Text Available This article examines the nature of scientific thought and looks at how "the scientific method" has propelled mankind's understanding of natural phenomena from the embryonic metaphysics to the present-day quantum and plasma physics. The scientific mind is always in search of ways to improve the present knowledge about nature, and is never satisfied that the present knowledge is "the truth, the whole truth and nothing but the truth". "Science is grounded on a firm foundation of doubt" - Don Cupitt. "The moderns have subjected the phenomena of nature to the laws of mathematics" - Isaac Newton. The scholastic adage, "all men by nature desire to know" has driven philosophers, from as far back as the Aristotelian era, to ponder the question "what are the conditions of knowing?", Or, simply put "how do you know that you know something?” Under what conditions can something be called knowledge?

  20. 50 CFR 216.45 - General Authorization for Level B harassment for scientific research.

    Science.gov (United States)

    2010-10-01

    ... aspects of the proposed research; (ii) The species or stocks of marine mammals (common and scientific names) that are the subject of the scientific research and any other species or stock of marine mammals... this section. Annual reports must include: (i) A summary of research activities conducted; (ii...

  1. "Biosphere Reserve"--The Actual Research Subject of the Sustainable Development Process"

    Science.gov (United States)

    Khasaev, Gabibulla R.; Sadovenko, Marina Yu.; Isaev, Roman O.

    2016-01-01

    The relevance of the analyzed issue is caused by the growing slippage of research funds of sustainable development in its practice. The purpose of the article is the theoretical basis of the biosphere reserve as a scientific research subject that is relevant to rules of the scientific activity. The leading approach to the study of this issue is…

  2. Possible reasons for low scientific literacy of Slovak students in some natural science subjects

    Science.gov (United States)

    Bellová, Renata; Melicherčíková, Danica; Tomčík, Peter

    2018-04-01

    Background: The results of international studies have concluded the low level of science literacy in natural science subjects of Slovak students. These studies also showed that this state can be positively influenced by various innovations, which are implemented into the teaching process of above-mentioned subjects.

  3. Engaging Pre-Service Teachers to Teach Science Contextually with Scientific Approach Instructional Video

    Science.gov (United States)

    Susantini, E.; Kurniasari, I.; Fauziah, A. N. M.; Prastowo, T.; Kholiq, A.; Rosdiana, L.

    2018-01-01

    Contextual teaching and learning/CTL presents new concepts in real-life experiences and situations where students can find out the meaningful relationship between abstract ideas and practical applications. Implementing contextual teaching by using scientific approach will foster teachers to find the constructive ways of delivering and organizing science content. This research developed an instructional video that represented a modeling of using a scientific approach in CTL. The aim of this research are to engage pre-service teachers in learning how to teach CTL and to show how pre-service teachers’ responses about learning how to teach CTL using an instructional video. The subjects of this research were ten pre-service teachers in Department of Natural Sciences, Universitas Negeri Surabaya, Indonesia. All subjects observed the instructional video which demonstrated contextual teaching and learning combined with the scientific approach as they completed a worksheet to analyze the video content. The results showed that pre-service teachers could learn to teach contextually as well as applying the scientific approach in science classroom through a modeling in the instructional video. They also responded that the instructional video could help them to learn to teach each component contextual teaching as well as scientific approach.

  4. WHY SCIENTIFIC RESEARCH OF A LECTURER IS THE «LAME HORSE» OF MODERN SCIENCE?

    Directory of Open Access Journals (Sweden)

    Maria A. Belyaeva

    2015-01-01

    Full Text Available The aim of the article is to represent reflections on the crisis of science and logical thinking (within the framework of Social Science, Humanities and higher education that has its local and global manifestations; the author focused own attention on the manifestations in order to understand its depth and possible ways of overcoming them. Methods. A number of theoretical methods have been used in the article: analysis and synthesis, induction and deduction, comparison and classification, methods of extrapolation and modeling, as well as participant observation. Results. Local manifestations of the crisis of science and logical thinking associated with human factor in the national system of higher professional education in the era of virtualization and commercialization are expressed in reducing efforts and productivity of scientific research, due to the existing contradictions between changed requirements that enumerate professional duties of a lecturer and possibilities of combining and productive implementation of traditional and new professional roles. In particular, researches turn to promoters of themselves to solve financial and organizational issues of a scientific research and promotion of ratings. Changes in the sense of scientific activity in respect to educators and their personal attitude to new requirements will eventually face the eternal problem of attitude to knowledge and to the actual problem of change of knowledge subject in non-classical model and post-non-classical model of science. Expression of a researcher’s individuality encounters many obstacles (the author has identified 10 of them and is complicated by new facets of this subjectivity, induced by «logistics turn point» in science. Scientific novelty. The author proves that it is necessary to change nonclassical subject knowledge model (where the corporate subject leaning for the general ways and collective norms of scientific activity dominates for

  5. Bridge over troubled water - valuing Russia's scientific landscape

    Czech Academy of Sciences Publication Activity Database

    Büntgen, Ulf

    2016-01-01

    Roč. 70, č. 1 (2016), s. 95-98 ISSN 0936-577X R&D Projects: GA MŠk(CZ) LO1415 Institutional support: RVO:67179843 Keywords : Environmental change * Brain drain * Interdisciplinary research * Paleo-archives * Russia * Scientific collaboration Subject RIV: EH - Ecology, Behaviour Impact factor: 1.578, year: 2016

  6. Criminal profiling as expert witness evidence: The implications of the profiler validity research.

    Science.gov (United States)

    Kocsis, Richard N; Palermo, George B

    The use and development of the investigative tool colloquially known as criminal profiling has steadily increased over the past five decades throughout the world. Coupled with this growth has been a diversification in the suggested range of applications for this technique. Possibly the most notable of these has been the attempted transition of the technique from a tool intended to assist police investigations into a form of expert witness evidence admissible in legal proceedings. Whilst case law in various jurisdictions has considered with mutual disinclination the evidentiary admissibility of criminal profiling, a disjunction has evolved between these judicial examinations and the scientifically vetted research testing the accuracy (i.e., validity) of the technique. This article offers an analysis of the research directly testing the validity of the criminal profiling technique and the extant legal principles considering its evidentiary admissibility. This analysis reveals that research findings concerning the validity of criminal profiling are surprisingly compatible with the extant legal principles. The overall conclusion is that a discrete form of crime behavioural analysis is supported by the profiler validity research and could be regarded as potentially admissible expert witness evidence. Finally, a number of theoretical connections are also identified concerning the skills and qualifications of individuals who may feasibly provide such expert testimony. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Heart rate profile during exercise in patients with early repolarization.

    Science.gov (United States)

    Cay, Serkan; Cagirci, Goksel; Atak, Ramazan; Balbay, Yucel; Demir, Ahmet Duran; Aydogdu, Sinan

    2010-09-01

    Both early repolarization and altered heart rate profile are associated with sudden death. In this study, we aimed to demonstrate an association between early repolarization and heart rate profile during exercise. A total of 84 subjects were included in the study. Comparable 44 subjects with early repolarization and 40 subjects with normal electrocardiogram underwent exercise stress testing. Resting heart rate, maximum heart rate, heart rate increment and decrement were analyzed. Both groups were comparable for baseline characteristics including resting heart rate. Maximum heart rate, heart rate increment and heart rate decrement of the subjects in early repolarization group had significantly decreased maximum heart rate, heart rate increment and heart rate decrement compared to control group (all P decrement (multiple-adjusted OR of the risk of presence of early repolarization was 2.98 (95%CI 1.21-7.34) (P = 0.018) and 7.73 (95%CI 2.84-21.03) (P decrement compared to higher levels, respectively. Subjects with early repolarization have altered heart rate profile during exercise compared to control subjects. This can be related to sudden death.

  8. Under-Representation of Women in Science: From Educational, Feminist and Scientific Views

    Science.gov (United States)

    Sarseke, Gulnar

    2018-01-01

    The article aims to explore the main reasons why women are under-represented in science, technology, engineering, and mathematics (STEM) subjects and careers. The article critically analyzes three approaches: educational, feminist, and scientific. This work highlights that the subject "gender and science" has been looked at for at least…

  9. Investigation of pH and Temperature Profiles in the GI Tract of Fasted Human Subjects Using the Intellicap(®) System.

    Science.gov (United States)

    Koziolek, Mirko; Grimm, Michael; Becker, Dieter; Iordanov, Ventzeslav; Zou, Hans; Shimizu, Jeff; Wanke, Christoph; Garbacz, Grzegorz; Weitschies, Werner

    2015-09-01

    Gastrointestinal (GI) pH and temperature profiles under fasted-state conditions were investigated in two studies with each 10 healthy human subjects using the IntelliCap(®) system. This telemetric drug delivery device enabled the determination of gastric emptying time, small bowel transit time, and colon arrival time by significant pH and temperature changes. The study results revealed high variability of GI pH and transit times. The gastric transit of IntelliCap(®) was characterized by high fluctuations of the pH with mean values ranging from pH 1.7 to pH 4.7. Gastric emptying was observed after 7-202 min (median: 30 min). During small bowel transit, which had a duration of 67-532 min (median: 247 min), pH values increased slightly from pH 5.9-6.3 in proximal parts to pH 7.4-7.8 in distal parts. Colonic pH conditions were characterized by values fluctuating mainly between pH 5 and pH 8. The pH profiles and transit times described in this work are highly relevant for the comprehension of drug delivery of solid oral dosage forms comprising ionizable drugs and excipients with pH-dependent solubility. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

  10. Polysome Profile Analysis - Yeast

    Czech Academy of Sciences Publication Activity Database

    Pospíšek, M.; Valášek, Leoš Shivaya

    2013-01-01

    Roč. 530, č. 2013 (2013), s. 173-181 ISSN 0076-6879 Institutional support: RVO:61388971 Keywords : grow yeast cultures * polysome profile analysis * sucrose density gradient centrifugation Subject RIV: CE - Biochemistry Impact factor: 2.194, year: 2013

  11. The Success Criteria of Scientific Pedagogic Activities

    Directory of Open Access Journals (Sweden)

    M. V. Ovchinnikov

    2013-01-01

    Full Text Available The paper considers the problem of scientific pedagogic activity assessment of the higher school academic staff. The existing options of quality estimation are listed along with their deficiencies; the most acceptable in the authors’ opinion being the systematic approach. The latter allows considering almost every aspect of scientific-pedagogic activity. On that ground, the authors recommend the following success estimation criteria: gnostic, projecting, communicative, informational, and organizational. The criteria of work satisfaction and its results are taken into consideration as additional ones. The indicators of each criterion are given demonstrating that the as- sessment can be both internal (subjective and external (objective, denoted in the normative acts. The problem of complex and just quality assessment of scientific- pedagogic activity is quite relevant as it affects the academic staff motivation. The authors believe that the research findings can improve the objectivity of teachers’ work assessment and give way to differentiated approaches to their motivation and stimulation. 

  12. Carotenoid profiling of leaves of selected eggplant accessions subjected to drought stress

    Science.gov (United States)

    This study focused on the quantification of carotenoids of the leaves of African eggplants commonly consumed as leafy and fruit vegetables. The results gave comparative profiles of carotenoids at different growth and developmental stages and under drought stress. Stress was achieved by limiting irri...

  13. On the growth of scientific knowledge: yeast biology as a case study.

    Directory of Open Access Journals (Sweden)

    Xionglei He

    2009-03-01

    Full Text Available The tempo and mode of human knowledge expansion is an enduring yet poorly understood topic. Through a temporal network analysis of three decades of discoveries of protein interactions and genetic interactions in baker's yeast, we show that the growth of scientific knowledge is exponential over time and that important subjects tend to be studied earlier. However, expansions of different domains of knowledge are highly heterogeneous and episodic such that the temporal turnover of knowledge hubs is much greater than expected by chance. Familiar subjects are preferentially studied over new subjects, leading to a reduced pace of innovation. While research is increasingly done in teams, the number of discoveries per researcher is greater in smaller teams. These findings reveal collective human behaviors in scientific research and help design better strategies in future knowledge exploration.

  14. Authors as vehicles of scientific memes

    Science.gov (United States)

    Krawczyk, M. J.; Kułakowski, K.

    2016-04-01

    Scientific memes have been defined as short units of text in a publication that are replicated in citing [T. Kuhn et al., Phys. Rev. X 4, 041036 (2014)]. Here, we investigate how often the meme appears in the title of the paper when driven by a coauthorship with somebody who has already published a paper with the same meme in the paper title. Five memes are investigated: traffic flow (TF), stochastic resonance (SR), key distribution (KD), small world (SW) and prisoner’s dilemma (PD). For each meme, a network of papers (GP) and network of authors (GA) are constructed. A meme index is proposed which is a measure how often scientific teams undertake the research on a given area, marked by the meme, without a cooperation with coauthors with previous achievements in the subject.

  15. Internalizing and externalizing personality and subjective effects in a sample of adolescent cannabis users.

    Science.gov (United States)

    García-Sánchez, Sara; Matalí, Josep Lluís; Martín-Fernández, María; Pardo, Marta; Lleras, Maria; Castellano-Tejedor, Carmina; Haro, Josep Maria

    2016-10-06

    Cannabis is the illicit substance most widely used by adolescents. Certain personality traits such as impulsivity and sensation seeking, and the subjective effects experienced after substance use (e.g. euphoria or relaxation) have been identified as some of the main etiological factors of consumption. This study aims to categorize a sample of adolescent cannabis users based on their most dominant personality traits (internalizing and externalizing profile). Then, to make a comparison of both profiles considering a set of variables related to consumption, clinical severity and subjective effects experienced. From a cross-sectional design, 173 adolescents (104 men and 69 women) aged 13 to 18 asking for treatment for cannabis use disorder in an Addictive Behavior Unit (UCAD) from the hospital were recruited. For the assessment, an ad hoc protocol was employed to register consumption, the Millon Adolescent Clinical Inventory (MACI) and the Addiction Research Center Inventory (ARCI) 49-item short form were also administered. Factor analysis suggested a two-profile solution: Introverted, Inhibited, Doleful, Dramatizing (-), Egotistic (-), Self-demeaning and Borderline tendency scales composed the internalizing profile, and Submissive (-), Unruly, Forceful, Conforming (-) and Oppositional scales composed the externalizing profile. The comparative analysis showed that the internalizing profile has higher levels of clinical severity and more subjective effects reported than the externalizing profile. These results suggest the need to design specific intervention strategies for each profile.

  16. Pharmacokinetics, Safety and Cognitive Function Profile of Rupatadine 10, 20 and 40 mg in Healthy Japanese Subjects: A Randomised Placebo-Controlled Trial.

    Directory of Open Access Journals (Sweden)

    Jörg Täubel

    Full Text Available Rupatadine is a marketed second generation antihistamine, with anti-PAF activity, indicated for symptomatic treatment of allergic rhinitis and urticaria. This study was conducted to evaluate the pharmacokinetics (PK, pharmacodynamics (PD, safety and tolerability of rupatadine in healthy Japanese subjects after single and multiple oral doses.In this randomised, double-blind, placebo-controlled study, 27 male and female healthy Japanese subjects were administered single and multiple escalating rupatadine dose of 10, 20 and 40 mg or placebo. Blood samples were collected at different time points for PK measurements and subjects were assessed for safety and tolerability. The effect of rupatadine on cognitive functioning was evaluated by means of computerized cognitive tests: rapid visual information processing (RVP, reaction time (RT, spatial working memory (SWM and visual analogue scales (VAS.Exposure to rupatadine as measured by Cmax and AUC was found to increase in a dose dependent manner over the dose range of 10-40 mg for both single and multiple dose administration. The safety assessments showed that all treatment related side effects were of mild intensity and there were no serious adverse events (SAEs or withdrawals due to treatment-emergent adverse events (TEAEs in this study. The therapeutic dose of rupatadine did not show any CNS impairment in any of the cognitive tests.This study demonstrated that rupatadine is safe and well tolerated by Japanese healthy subjects. The PK-PD profile confirmed previous experience with rupatadine.

  17. Scientific instruments, scientific progress and the cyclotron

    International Nuclear Information System (INIS)

    Baird, David; Faust, Thomas

    1990-01-01

    Philosophers speak of science in terms of theory and experiment, yet when they speak of the progress of scientific knowledge they speak in terms of theory alone. In this article it is claimed that scientific knowledge consists of, among other things, scientific instruments and instrumental techniques and not simply of some kind of justified beliefs. It is argued that one aspect of scientific progress can be characterized relatively straightforwardly - the accumulation of new scientific instruments. The development of the cyclotron is taken to illustrate this point. Eight different activities which promoted the successful completion of the cyclotron are recognised. The importance is in the machine rather than the experiments which could be run on it and the focus is on how the cyclotron came into being, not how it was subsequently used. The completed instrument is seen as a useful unit of scientific progress in its own right. (UK)

  18. Striving for Scientific Integrity and Ethical Practices in Higher Education

    Science.gov (United States)

    Geissman, J. W.

    2017-12-01

    The need for the highest levels of scientific integrity and ethical principles in higher education, globally, is obvious. This is the setting where faculty scientists practice and future scientists, as entering science majors, those who change course and switch to science, and graduate students, are nurtured and mentored. Institutions of higher education across the globe are devoting increasing attention to scientific integrity and ethical practices, often as mandated by specific (funding) agencies, and this certainly is a step in the right direction. One approach has involved graduate students, particularly PhD students, in formal classes/seminars on the subjects. Another, more institution-specific, is to require freshman science majors to take one or more classes designed to assist students, in many ways, to succeed in whatever science path they choose. For the past five years I have "taught" such a class, which I like to refer to as "Science is the Rest of Your Life 101". My section is very heavy on scientific integrity and ethical practices; most students have never been exposed to nor have considered such subjects. Their interest level is exceedingly keen. So, steps are being taken, but rectifying existing concerns will take time. Here are some (potential/real) problems. One facing all of higher education is the ever decreasing number, certainly in the United States, of tenured/tenure track faculty in all disciplines together with the generational "gap" or "double gap" (some colleagues of mine are in their 80s) between those who never for all intents and purposes received any "formal" exposure to scientific integrity and ethical practices issues and those fresh in the academy for which these subjects are recently and better engrained. At most institutions, those faculty never involved in such formal training because of, well, their age, are required to pass some form of on-line "certification" class in research ethics among other subjects on an annual or bi

  19. Role of lifestyle variables on the lipid profile of selected South Indian subjects

    Directory of Open Access Journals (Sweden)

    Uma Chitra

    2012-01-01

    Conclusion: Our results confirm that diet and exercise routines significantly affect the serum lipid profile. Obesity and overweight constitute a risk factor for the development of hypercholesterolaemia and hypertriglyceridaemia.

  20. RASopathies are associated with a distinct personality profile.

    Science.gov (United States)

    Bizaoui, Varoona; Gage, Jessica; Brar, Rita; Rauen, Katherine A; Weiss, Lauren A

    2018-06-01

    Personality is a complex, yet partially heritable, trait. Although some Mendelian diseases like Williams-Beuren syndrome are associated with a particular personality profile, studies have failed to assign the personality features to a single gene or pathway. As a family of monogenic disorders caused by mutations in the Ras/MAPK pathway known to influence social behavior, RASopathies are likely to provide insight into the genetic basis of personality. Eighty subjects diagnosed with cardiofaciocutaneous syndrome, Costello syndrome, neurofibromatosis type 1, and Noonan syndrome were assessed using a parent-report BFQ-C (Big Five Questionnaire for Children) evaluating agreeableness, extraversion, conscientiousness, intellect/openness, and neuroticism, along with 55 unaffected sibling controls. A short questionnaire was added to assess sense of humor. RASopathy subjects and sibling controls were compared for individual components of personality, multidimensional personality profiles, and individual questions using Student tests, analysis of variance, and principal component analysis. RASopathy subjects were given lower scores on average compared to sibling controls in agreeableness, extraversion, conscientiousness, openness, and sense of humor, and similar scores in neuroticism. When comparing the multidimensional personality profile between groups, RASopathies showed a distinct profile from unaffected siblings, but no difference in this global profile was found within RASopathies, revealing a common profile for the Ras/MAPK-related disorders. In addition, several syndrome-specific strengths or weaknesses were observed in individual domains. We describe for the first time an association between a single pathway and a specific personality profile, providing a better understanding of the genetics underlying personality, and new tools for tailoring educational and behavioral approaches for individuals with RASopathies. © 2018 Wiley Periodicals, Inc.

  1. Perception of facial profile attractiveness of a brown subject displaying different degrees of lip projection or retrusion, in the city of Salvador/Bahia

    Directory of Open Access Journals (Sweden)

    Elizabete Nobre Carneiro

    Full Text Available ABSTRACT Introduction: The attractiveness and facial aesthetics are commonly defined by the media in modern society and the number of patients seeking for changes in the facial appearance is progressively increasing. Augmented face convexity is believed to be non aesthetic and among the treatments available for its correction, the extraction of premolars followed by anterior teeth retraction produces a significant effect. However, it is questionable whether the procedure is reasonable in brown and black patients, since dental protrusion is considered a common morphological feature in these groups. Methods: A photograph of a brown female subject was manipulated with image-editing program to generate a set of images with different degrees of labial retraction/protrusion. Two hundred individuals, randomly selected, were asked to rate each photograph and select which one showed the best aesthetic appearance. The survey was carried out in Salvador / Bahia (Brazil, which is a city with strong African slavery background and high proportion of brown and black population. Results: Regardless of color, sex or income, the interviewees chose primarily the straight facial profile and secondarily the slightly concave or convex as more pleasant for a brown female individual (p< 0.05. The moderate and extreme convexity had the lowest scores (p< 0.05. Conclusions: It is suggested that among the accessed population, straight and slightly convex or concave profiles were preferred for a brown subject and moderate or excessive facial protrusion were not well accepted. It is expected that these data can guide orthodontists about the need for extraction to reduce dental protrusion in brown patients.

  2. Scientific Production on Open Access: A Worldwide Bibliometric Analysis in the Academic and Scientific Context

    Directory of Open Access Journals (Sweden)

    Sandra Miguel

    2016-01-01

    Full Text Available This research aims to diachronically analyze the worldwide scientific production on open access, in the academic and scientific context, in order to contribute to knowledge and visualization of its main actors. As a method, bibliographical, descriptive and analytical research was used, with the contribution of bibliometric studies, especially the production indicators, scientific collaboration and indicators of thematic co-occurrence. The Scopus database was used as a source to retrieve the articles on the subject, with a resulting corpus of 1179 articles. Using Bibexcel software, frequency tables were constructed for the variables, and Pajek software was used to visualize the collaboration network and VoSViewer for the construction of the keywords’ network. As for the results, the most productive researchers come from countries such as the United States, Canada, France and Spain. Journals with higher impact in the academic community have disseminated the new constructed knowledge. A collaborative network with a few subnets where co-authors are from different countries has been observed. As conclusions, this study allows identifying the themes of debates that mark the development of open access at the international level, and it is possible to state that open access is one of the new emerging and frontier fields of library and information science.

  3. Thyroid profile and autoantibodies in Type 1 diabetes subjects: A perspective from Eastern India

    Directory of Open Access Journals (Sweden)

    Debmalya Sanyal

    2017-01-01

    Full Text Available Context: There has been a rise in the incidence of type 1 diabetes mellitus (T1DM in India. The prevalence of thyroid autoantibodies and thyroid dysfunction is common in T1DM. Aims: The aim of this study is to determine the incidence of thyroid dysfunction and thyroid autoantibodies in T1DM subjects, without any history of thyroid disease, and the prevalence of glutamic acid decarboxylase (GAD antibody, Islet antigen-2 antibody (IA2, thyroid peroxidase (TPO, and thyroglobulin autoantibodies (Tg-AB in T1DM subjects. Settings and Design: This was a cross-sectional clinical-based study. Subjects and Methods: Fifty subjects (29 males, 31 females with T1DM and without any history of thyroid dysfunction were included in the study. All subjects were tested for GAD antibody, IA2 antibody, TPO antibody, thyroglobulin antibody, free thyroxine, and thyroid-stimulating hormone. Statistical Analysis Used: A Chi-square/pooled Chi-square test was used to assess the trends in the prevalence of hypothyroidism. A two-tailed P< 0.05 was considered statistically significant. Results: The mean age of the subjects was 23.50 years. 9.8% of subjects were below the age of 12 years, 27.45% of subjects were of age 12–18 years, 37.25% of subjects were of age 19–30 years, and 25.49% of subjects were above 30 years. 78% were positive autoantibody for GAD, 30% for IA-2, 24% for TPO, and 16% were positive for Tg-AB. A total of 6.0% of T1DM subjects had evidence of clinical hypothyroidism, but the prevalence of subclinical hyperthyroidism (SCH varied from 32% to 68.0% for we considered different definitions of SCH as advocated by different guidelines. All subjects with overt hypothyroidism had positive GAD and thyroid autoantibodies. One (2% subject had clinical hyperthyroidism with strongly positive GAD, TPO, and Tg-AB. Conclusions: We found a high prevalence of GAD, IA2, TPO, and Tg-AB in our T1DM subjects. A substantial proportion of our subjects had undiagnosed thyroid

  4. Homogenization of the lipid profile values.

    Science.gov (United States)

    Pedro-Botet, Juan; Rodríguez-Padial, Luis; Brotons, Carlos; Esteban-Salán, Margarita; García-Lerín, Aurora; Pintó, Xavier; Lekuona, Iñaki; Ordóñez-Llanos, Jordi

    Analytical reports from the clinical laboratory are essential to guide clinicians about what lipid profile values should be considered altered and, therefore, require intervention. Unfortunately, there is a great heterogeneity in the lipid values reported as "normal, desirable, recommended or referenced" by clinical laboratories. This can difficult clinical decisions and be a barrier to achieve the therapeutic goals for cardiovascular prevention. A recent international recommendation has added a new heterogeneity factor for the interpretation of lipid profile, such as the possibility of measuring it without previous fasting. All this justifies the need to develop a document that adapts the existing knowledge to the clinical practice of our health system. In this regard, professionals from different scientific societies involved in the measurement and use of lipid profile data have developed this document to establish recommendations that facilitate their homogenization. Copyright © 2017. Publicado por Elsevier España, S.L.U.

  5. Effect of Using Scientific Calculators in Learning Mathematics by ...

    African Journals Online (AJOL)

    Mathematics plays a crucial role in technological development of any country; attainment in the subject determines the rate of adoption of appropriate technology and industrialization. In Kenya mathematics is compulsory in primary and at secondary school level. Use of scientific calculators was introduced in Kenya ...

  6. Study of Scientific Production of Community Medicines' Department Indexed in ISI Citation Databases.

    Science.gov (United States)

    Khademloo, Mohammad; Khaseh, Ali Akbar; Siamian, Hasan; Aligolbandi, Kobra; Latifi, Mahsoomeh; Yaminfirooz, Mousa

    2016-10-01

    In the scientometric, the main criterion in determining the scientific position and ranking of the scientific centers, particularly the universities, is the rate of scientific production and innovation, and in all participations in the global scientific development. One of the subjects more involved in repeatedly dealt with science and technology and effective on the improvement of health is medical science fields. In this research using scientometric and citation analysis, we studied the rate of scientific productions in the field of community medicine, which is the numbers of articles published and indexed in ISI database from 2000 to 2010. This study is scientometric using the survey and analytical citation. The study samples included all of the articles in the ISI database from 2000 to 2010. For the data collection, the advance method of searching was used at the ISI database. The ISI analyses software and descriptive statistics were used for data analysis. Results showed that among the five top universities in producing documents, Tehran University of Medical Sciences with 88 (22.22%) documents are allocated to the first rank of scientific products. M. Askarian with 36 (90/9%) published documents; most of the scientific outputs in Community medicine, in the international arena is the most active author in this field. In collaboration with other writers, Iranian departments of Community Medicine with 27 published articles have the greatest participation with scholars of English authors. In the process of scientific outputs, the results showed that the scientific process was in its lowest in the years 2000 to 2004, and while the department of Community medicine in 2009 allocated most of the production process to itself. Iranian Journal of Public Health and Saudi Medical Journal each of them had 16 articles which had most participation rate in the publishing of community medicine's department. On the type of carrier, community medicine's department by

  7. The future is yours--Get ready! Career options in scientific and technical fields. Revision

    Energy Technology Data Exchange (ETDEWEB)

    1992-10-01

    This 50 page brochure was developed by Brookhaven National Laboratory to encourage high school students to begin considering careers in the scientific and technical fields. The topics of the brochure include career selection, career options, a review of training required for each occupation, a collection of profiles of BNL employees describing how they chose and prepared for their careers, a description of BNL educational programs for high school students, and profiles of some of the students participating in these programs.

  8. On superconductivity and superfluidity. A scientific autobiography

    International Nuclear Information System (INIS)

    Ginzburg, Vitaly L.

    2009-01-01

    This book presents the Nobel Laureate Vitaly Ginzburg's views on the development in the field of superconductivity. It contains a selection of Ginzburg's key writings, including his amended version of the Nobel lecture in Physics 2003. Also included are an expanded autobiography, which was written for the Nobel Committee, an article entitled ''A Scientific Autobiography: An Attempt,'' a fundamental article co-written with L.D. Landau entitled ''To the theory of superconductivity,'' an expanded review article ''Superconductivity and superfluidity (what was done and what was not done),'' and some newly written short articles about superconductivity and related subjects. So, in toto, presented here are the personal contributions of Ginzburg, that resulted in the Nobel Prize, in the context of his scientific biography. (orig.)

  9. On superconductivity and superfluidity a scientific autobiography

    CERN Document Server

    Ginzburg, Vitalii Lazarevich

    2009-01-01

    This book presents the Nobel Laureate Vitaly Ginzburg's views on the development in the field of superconductivity. It contains a selection of Ginzburg's key writings, including his amended version of the Nobel lecture in Physics 2003. Also included are an expanded autobiography, which was written for the Nobel Committee, an article entitled "A Scientific Autobiography: An Attempt," a fundamental article co-written with L.D. Landau entitled "To the theory of superconductivity," an expanded review article "Superconductivity and superfluidity (what was done and what was not done)," and some newly written short articles about superconductivity and related subjects. So, in toto, presented here are the personal contributions of Ginzburg, that resulted in the Nobel Prize, in the context of his scientific biography.

  10. Executive function impairment in community elderly subjects with questionable dementia.

    Science.gov (United States)

    Lam, Linda C W; Lui, Victor W C; Chiu, Helen F K; Chan, Sandra S M; Tam, Cindy W C

    2005-01-01

    The neurocognitive profile of community-dwelling Chinese subjects with 'questionable' dementia was studied. One hundred and fifty-four ambulatory Chinese subjects were recruited from local social centers for the elderly. Each subject was examined using the Clinical Dementia Rating (CDR), the Cantonese version of the Mini-Mental State Examination (CMMSE), the Chinese version of the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog), the Category Verbal Fluency Test (CVFT), digit and visual span tests, and the Cambridge Neurological Inventory. The neurocognitive profile of nondemented subjects (CDR 0) was compared with that of subjects with 'questionable' dementia (CDR 0.5). Subjects with 'questionable' dementia were older, and had lower educational levels and global cognitive assessment scores than the controls (CMMSE and ADAS-Cog; t tests, p < 0.001). In addition, they also had significantly lower scores in delayed recall, reverse span, verbal fluency tests and worse performance in complex motor tasks related to executive function (Mann-Whitney tests, p < 0.001). Logistic regression analysis revealed that ADAS-Cog, CVFT, and reverse visual span were significant predictors for the CDR of 'questionable' dementia. Aside from memory impairment, executive function deficits were also present in subjects with 'questionable' dementia. To identify groups cognitively at risk for dementia, concomitant assessments of memory and executive function are suggested.

  11. The exceptional ethics of the investigator-subject relationship.

    Science.gov (United States)

    Sachs, Benjamin

    2010-02-01

    This article concerns the validity of six canonical rules that institutional review boards use to constrain the behavior of investigators. These rules require investigators to design their studies in a scientifically valid way, not pay their subjects to take risks, minimize risks to their subjects, secure for their subjects access to effective interventions post-trial, not pay their subjects too much and allow their subjects to withdraw from the study unconditionally. Enforcement of these rules is problematic because there are other relationships that seem to be like the investigator-subject relationship in all ethically relevant respects, such as the employer-employee and volunteer organizer-volunteer relationships, to which we would not dream of applying these same rules. Applying these rules in one context but not the others is a violation of ethical consistency I label "exceptionalism." We should conclude that it is time to reexamine the validity of the six rules.

  12. Effects of Ramadan Fasting on Lipid Profile: A Narrative Review

    OpenAIRE

    Mohsen Mazidi; Peyman Rezaie; Ehsan Karimi; Mohsen Nematy

    2014-01-01

    Ramadan Fasting during the month of Ramadan is a religious obligation, practiced by millions of people around the world. Ramadan fasting is essentially a fundamental change in lifestyle for one lunar month. This type of fasting may have significant effects on lipid profile. Although there is no scientific consensus about the effects of fasting on cardiovascular risks such as changes in lipid profile, some studies have revealed the positive effects of Ramadan fasting (and similar religious fas...

  13. SALTON SEA SCIENTIFIC DRILLING PROJECT: SCIENTIFIC PROGRAM.

    Science.gov (United States)

    Sass, J.H.; Elders, W.A.

    1986-01-01

    The Salton Sea Scientific Drilling Project, was spudded on 24 October 1985, and reached a total depth of 10,564 ft. (3. 2 km) on 17 March 1986. There followed a period of logging, a flow test, and downhole scientific measurements. The scientific goals were integrated smoothly with the engineering and economic objectives of the program and the ideal of 'science driving the drill' in continental scientific drilling projects was achieved in large measure. The principal scientific goals of the project were to study the physical and chemical processes involved in an active, magmatically driven hydrothermal system. To facilitate these studies, high priority was attached to four areas of sample and data collection, namely: (1) core and cuttings, (2) formation fluids, (3) geophysical logging, and (4) downhole physical measurements, particularly temperatures and pressures.

  14. Roentgenographic evaluation of the profiles for young male and female

    Energy Technology Data Exchange (ETDEWEB)

    Park, Tae Won [Department of Radiology, College of Dentistry, Seoul National University, Seoul (Korea, Republic of)

    1975-11-15

    The author has studied on the profiles on Korean young male and female by the cephalometric roentgenograms, and the subjects consisted of 104 persons with normal occlusion, and the measurements were done on the soft and hard structures. The mean and standard deviations in the subjects were calculated and compared between male and female. The author has obtained the following results: 1. In the linear measurement, male was longer than female in most measuring points. 2. Compared with the angulation of soft tissue, there were no differences between both sexes. 3. In the skeletal patterns, there were some differences between male and female, but there was a similarity to the facial profile. 4. The individual variations on the cephalometric profiles on the subjects were recognized, especially, in the lower facial part.

  15. Scientific production of medical sciences universities in north of iran.

    Science.gov (United States)

    Siamian, Hasan; Firooz, Mousa Yamin; Vahedi, Mohammad; Aligolbandi, Kobra

    2013-01-01

    NONE DECLARED. The study of the scientific evidence citation production by famous databases of the world is one of the important indicators to evaluate and rank the universities. The study at investigating the scientific production of Northern Iran Medical Sciences Universities in Scopus from 2005 through 2010. This survey used scientometrics technique. The samples under studies were the scientific products of four northern Iran Medical universities. Viewpoints quantity of the Scientific Products Mazandaran University of Medical Sciences stands first and of Babol University of Medical Sciences ranks the end, but from the viewpoints of quality of scientific products of considering the H-Index and the number of cited papers the Mazandaran University of Medical Sciences is a head from the other universities under study. From the viewpoints of subject of the papers, the highest scientific products belonged to the faculty of Pharmacy affiliated to Mazandaran University of Medial Sciences, but the three other universities for the genetics and biochemistry. Results showed that the Mazandaran University of Medical Sciences as compared to the other understudies universities ranks higher for the number of articles, cited articles, number of hard work authors and H-Index of Scopus database from 2005 through 2010.

  16. Percentage-based Author Contribution Index: a universal measure of author contribution to scientific articles.

    Science.gov (United States)

    Boyer, Stéphane; Ikeda, Takayoshi; Lefort, Marie-Caroline; Malumbres-Olarte, Jagoba; Schmidt, Jason M

    2017-01-01

    Deciphering the amount of work provided by different co-authors of a scientific paper has been a recurrent problem in science. Despite the myriad of metrics available, the scientific community still largely relies on the position in the list of authors to evaluate contributions, a metric that attributes subjective and unfounded credit to co-authors. We propose an easy to apply, universally comparable and fair metric to measure and report co-authors contribution in the scientific literature. The proposed Author Contribution Index (ACI) is based on contribution percentages provided by the authors, preferably at the time of submission. Researchers can use ACI to compare the contributions of different authors, describe the contribution profile of a particular researcher or analyse how contribution changes through time. We provide such an analysis based on contribution percentages provided by 97 scientists from the field of ecology who voluntarily responded to an online anonymous survey. ACI is simple to understand and to implement because it is based solely on percentage contributions and the number of co-authors. It provides a continuous score that reflects the contribution of one author as compared to the average contribution of all other authors. For example, ACI(i) = 3, means that author i contributed three times more than what the other authors contributed on average. Our analysis comprised 836 papers published in 2014-2016 and revealed patterns of ACI values that relate to career advancement. There are many examples of author contribution indices that have been proposed but none has really been adopted by scientific journals. Many of the proposed solutions are either too complicated, not accurate enough or not comparable across articles, authors and disciplines. The author contribution index presented here addresses these three major issues and has the potential to contribute to more transparency in the science literature. If adopted by scientific journals, it

  17. Students' Attitudes to Information in the Press: Critical Reading of a Newspaper Article With Scientific Content

    Science.gov (United States)

    Oliveras, B.; Márquez, C.; Sanmartí, N.

    2014-08-01

    This research analyses what happens when a critical reading activity based on a press article dealing with an energy-related problem is implemented with two groups of students of 13-14 years old and 16-17 years old in the same school (a total of 117 students). Specifically, the research analyses the students' profiles from the standpoint of their attitudes to the information given in the news story and the use they make of it when writing an argumentative text. It also analyses the difficulties the students have when it comes to applying their knowledge about energy in a real-life context. Lastly, some strategies are suggested for helping students to critically analyse the scientific content of a newspaper article. Three reader profiles were identified (the credulous reader, the ideological reader and the critical reader). No significant differences were found in reading profiles in terms of age or scientific knowledge. The findings show that the activity helped to link science learning in school with facts relating to an actual context, particularly in the case of students with more science knowledge.

  18. Software quality and process improvement in scientific simulation codes

    Energy Technology Data Exchange (ETDEWEB)

    Ambrosiano, J.; Webster, R. [Los Alamos National Lab., NM (United States)

    1997-11-01

    This report contains viewgraphs on the quest to develope better simulation code quality through process modeling and improvement. This study is based on the experience of the authors and interviews with ten subjects chosen from simulation code development teams at LANL. This study is descriptive rather than scientific.

  19. Statistical regularities in the rank-citation profile of scientists.

    Science.gov (United States)

    Petersen, Alexander M; Stanley, H Eugene; Succi, Sauro

    2011-01-01

    Recent science of science research shows that scientific impact measures for journals and individual articles have quantifiable regularities across both time and discipline. However, little is known about the scientific impact distribution at the scale of an individual scientist. We analyze the aggregate production and impact using the rank-citation profile c(i)(r) of 200 distinguished professors and 100 assistant professors. For the entire range of paper rank r, we fit each c(i)(r) to a common distribution function. Since two scientists with equivalent Hirsch h-index can have significantly different c(i)(r) profiles, our results demonstrate the utility of the β(i) scaling parameter in conjunction with h(i) for quantifying individual publication impact. We show that the total number of citations C(i) tallied from a scientist's N(i) papers scales as [Formula: see text]. Such statistical regularities in the input-output patterns of scientists can be used as benchmarks for theoretical models of career progress.

  20. For the Anniversary Edition of the Scientific Journal European Researcher. Series A – 110 issue

    OpenAIRE

    Goran Rajović; JelisavkaBulatović

    2016-01-01

    This article is a review of the jubilee scientific journal "European Researcher. Series A ", marked at all in 2016 – the sixth anniversary, of regular and of continuous publication. In addition to the history of the newspaper are exposed to the development phase of its program concept. The journal is the period 2010 – 2016 year, profiled in an important factor of development and the formation of professional and scientific thought. Journal “European Research. Series A” is now open forum for p...

  1. [Significance of the doctorate in scientific medical education].

    Science.gov (United States)

    Frosch, Matthias

    2018-02-01

    According to European and German law, the medical education of physicians must take place in a scientific degree program at a university or under the supervision of a university. To keep up the ideal of a scientific degree program, various organizations and associations, such as the German Research Foundation, the German Council of Science and Humanities and the German Medical Faculty Association, see the need for an even stronger anchoring of academic learning content in the course of study. Traditionally, a scientific project, which is carried out during the studies, provides the basis for the Doctor of Medicine (Dr. med.) after graduation, although the research projects as a basis for medical degrees are currently not obligatory parts of the curricula. The number of medical students performing such research projects is significantly decreasing, thus they are missing major skills for working in science. To counteract these developments, faculties of medicine are currently developing model curricula including deepened scientific education. Despite these efforts, the German Association of Faculties of Medicine argues that the performance of research projects leading to the doctoral degree is most suitable for obtaining expertise in scientific work. According to recommendations by the German Council of Science on the requirements for quality assurance of graduation doctoral degree programs have been introduced. This and further measures, like MD/PhD programs or research-based additional study programs serving the scientific qualification of medical students, are the subject of this article.

  2. EPISTEMOLOGICAL PERCEPTION AND SCIENTIFIC LITERACY IN LEVEL HIGH SCHOOL TEACHERS

    Directory of Open Access Journals (Sweden)

    Ramiro Álvarez-Valenzuela

    2016-07-01

    Full Text Available Research in science education has helped to find some difficulties that hinder the teaching-learning process. These problems include conceptual content of school subjects, the influence of prior knowledge of the student and the teachers have not been trained in their university education epistemologically. This research presents the epistemological conceptions of a sample of 114 high school teachers university science area, which refer the ideas about the role of observation in scientific knowledge development and the work of scientists in the process of knowledge generation. It also includes the level of scientific literacy from the literature that is used as a source of information on the teaching. The result also identifies the level of scientific literacy in students and their influence on learning.

  3. Scientific Investigation with the SJCSI

    Science.gov (United States)

    Berbey, E.; Delpeyroux, G.; Douay, E.; Juchereau, C.; Garavet, O.

    2012-04-01

    Scientific Investigation with the SJCSI (Saint Jean* Crime Scene Investigation) Our work, which we have been teaching for 3 years, consists of a scientific investigation. We create a case from A to Z and then our students (15 to 16 years old) are meant to collect samples and clues from a reconstituted crime scene and then have to catch the culprit thanks to laboratory tests crossing four subjects: Physics and Chemistry, Biology, Math and English. I'm a biology teacher and I work with 3 other teachers in my school. The objectives of these activities are: • Make sciences more attractive by putting them into a context of crime investigation. • Use science techniques to find a culprit or to clear a suspect. • To acquire scientific knowledge. • Realize that the different scientific subjects complement each other to carry out a survey. • Use English language and improve it. The investigation consists of doing experiments after collecting different samples and clues on the crime scene. Examples of Biology experimentation: • Detecting the origin of the blood samples found on the crime scene. Students observe blood samples with a microscope and compare the characteristics to those of human blood found on the web. They discover that blood samples found aren't human blood because the red cells have a nucleus. By using the information given in the scenario, they discover that blood sample belongs to the parrot of a suspect. Students, also take a photo of their microscopic preparations, add title and caption and so they learn the cell's structure and the characteristics of blood cells. • In another case, students have to study the blood sample found under the victims fingernails. They observe blood preparation and compare it to the blood of a suspect who has a genetic disease: drepanocytosis. So, they discover the characteristics of blood cells by comparing them to sickle cells. • DNA electrophoresis to identify DNA found, for example, on the gun. • Blood type

  4. Internet website as a tool of communication in scientific institutions

    Directory of Open Access Journals (Sweden)

    Marzena Feldy

    2015-12-01

    Full Text Available The aim of the article is to analyze the use of websites in communication activities and image building of national scientific institutions. One of the reasons for undertaking this subject is the greater attention paid to scientific communication and its link to the need for society involvement in research, that was expressed in the “Rome Declaration on Responsible Research and Innovation in Europe” in 2014. Apart from that, there is an enhanced science mediatization that requires from PR specialists an extra effort to ensure that their messages are not distorted. The subject seems to be vital as there is a growing emphasis on commercialization of scientific research that creates the need to undertake deliberate efforts to popularize scientific discoveries. Moreover, a demographic decline, which more and more touches higher education institutions and forces them to strive for creating well-known brands, contributes to the subject’s importance. In order to realize the objective, in July 2015, 605 websites of national research institutions were reviewed to determine whether their operators shared contact details to the employee responsible for communication, posted messages informing about current events as well as visual content, used such tools as newsletters, RSS feeds and social media, utilized solutions that facilitate contacts with experts and reprinted materials about themselves published by other medias. The analyzes were performed taking into account the type of each scientific institution (i.e.: a public university, a private university, a research institute or the PAS institute, its size and the empowerment to award scientific degrees. The results show that relatively few scientific institutions fully exploit the potential of websites in public relations activities. According to anticipation, scientific institutions with a department or at least a single position responsible for communication are more active in this field

  5. Sources of inspiration? Making sense of scientific references in patents

    NARCIS (Netherlands)

    Callaert, Julie; Pellens, Maikel; van Looy, Bart

    2013-01-01

    Scientific references in patent documents can be used as indicators signaling science-technology interactions. Whether they reflect a direct ‘knowledge flow’ from science to technology is subject of debate. Based on 33 interviews with inventors at Belgian firms and knowledge-generating institutes

  6. Scientific Approach to Improve Mathematical Problem Solving Skills Students of Grade V

    Science.gov (United States)

    Roheni; Herman, T.; Jupri, A.

    2017-09-01

    This study investigates the skills of elementary school students’ in problem solving through the Scientific Approach. The purpose of this study is to determine mathematical problem solving skills of students by using Scientific Approach is better than mathematical problem solving skills of students by using Direct Instruction. This study is using quasi-experimental method. Subject of this study is students in grade V in one of state elementary school in Cirebon Regency. Instrument that used in this study is mathematical problem solving skills. The result of this study showed that mathematical problem solving skills of students who learn by using Scientific Approach is more significant than using Direct Instruction. Base on result and analysis, the conclusion is that Scientific Approach can improve students’ mathematical problem solving skills.

  7. Apollo's scientific legacy

    International Nuclear Information System (INIS)

    Meadows, J.

    1979-01-01

    The scientific value and importance of the Apollo lunar programme is assessed in the light of data obtained both from the lunar surface itself and also from the command modules which orbited above. It is stated that much of the material they returned still awaits a detailed examination and that the cooperative teams set up to handle the lunar material have established new methods and standards of analysis, which are currently revitalising the old science of meteoritics. The new forms of organised research have also been carried over in the rapidly developing subject of planetary science. It is concluded that whatever the motives for launching the Apollo missions, planetary scientists have been in a much better position to understand the Solar System since then. (UK)

  8. EFSA Scientific Committee; Scientific Opinion on Risk Assessment Terminology

    DEFF Research Database (Denmark)

    Hald, Tine

    of improving the expression and communication of risk and/or uncertainties in the selected opinions. The Scientific Committee concluded that risk assessment terminology is not fully harmonised within EFSA. In part this is caused by sectoral legislation defining specific terminology and international standards......The Scientific Committee of the European Food Safety Authority (EFSA) reviewed the use of risk assessment terminology within its Scientific Panels. An external report, commissioned by EFSA, analysed 219 opinions published by the Scientific Committee and Panels to recommend possible ways......, the Scientific Committee concludes that particular care must be taken that the principles of CAC, OIE or IPPC are followed strictly. EFSA Scientific Panels should identify which specific approach is most useful in dealing with their individual mandates. The Scientific Committee considered detailed aspects...

  9. Cosmetic mesotherapy: between scientific evidence, science fiction, and lucrative business.

    Science.gov (United States)

    Atiyeh, Bishara S; Ibrahim, Amir E; Dibo, Saad A

    2008-11-01

    Mesotherapy, originally conceived in Europe, is a minimally invasive technique that consists of the intra- or subcutaneous injection of variable mixtures of natural plant extracts, homeopathic agents, pharmaceuticals, vitamins, and other bioactive substances in microscopic quantities through dermal multipunctures. Its application in cosmetic medicine and surgery is gaining in popularity and acceptance and is rapidly growing in profile at an alarming rate. Despite their attraction as purported rejuvenating and ''fat-dissolving'' injections, the safety and efficacy of these novel cosmetic treatments remain ambiguous, making mesotherapy vulnerable to criticism by the generally more skeptical medical community. The technique is shrouded in mystery and the controversy surrounding it pertains to its efficacy and potential adverse effects that are subject of much concern. As with any new technology, it is important to assess the benefits, safety, experience, and standardization of mesotherapy. More studies are necessary before it can be advocated as a safe and effective treatment for body contouring and facial rejuvenation. Although the claims made about mesotherapy may be hard to believe at face value, we must be cautious about rejecting new ideas. Just as absence of proof is not proof of absence, lack of scientific validation is not proof that it does not work.

  10. Who is the Scientist-Subject? A Critique of the Neo-Kantian Scientist-Subject in Lorraine Daston and Peter Galison’s Objectivity

    NARCIS (Netherlands)

    Shah, Esha

    2017-01-01

    The main focus of this essay is to closely engage with the role of scientist-subjectivity in the making of objectivity in Lorraine Daston and Peter Galison’s book Objectivity, and Daston’s later and earlier works On Scientific Observation and The Moral Economy of Science. I have posited four

  11. Dissonance: scientific paradigms underpinning the study of sound in geography

    Directory of Open Access Journals (Sweden)

    Daniel Paiva

    2018-05-01

    Full Text Available The objective of this article is to approach the different conceptions of sound – and its relations to the underlying scientific paradigms – that emerged throughout the history of geography. There has been a growing interest among geographers in understanding the spatialities of sound, and geographies of sound have become an emerging subfield of the discipline. For this reason, it is the right time to address how the discipline has approached sound throughout its history. Several theoretical perspectives influenced geography in the twentieth century, changing its methodologies and how its subjects were conceived. Sound, like other subjects, has been conceived very differently by geographers of competing paradigms. Concepts such as noise, soundscape, or sound as affect, among others, have dominated geographies of sound at specific periods. Due to the marginality of the subject in the discipline, assessments of these conceptual shifts are rare. I tackle this issue in this article as I provide a first attempt of writing a history of sound in geography. The article reviews debates regarding the name of the subfield, and the conceptions of sound in the successive and competing scientific paradigms in geography.

  12. The subjectivity of scientists and the Bayesian approach

    CERN Document Server

    Press, James S

    2001-01-01

    Comparing and contrasting the reality of subjectivity in the work of history's great scientists and the modern Bayesian approach to statistical analysisScientists and researchers are taught to analyze their data from an objective point of view, allowing the data to speak for themselves rather than assigning them meaning based on expectations or opinions. But scientists have never behaved fully objectively. Throughout history, some of our greatest scientific minds have relied on intuition, hunches, and personal beliefs to make sense of empirical data-and these subjective influences have often a

  13. On superconductivity and superfluidity. A scientific autobiography

    Energy Technology Data Exchange (ETDEWEB)

    Ginzburg, Vitaly L. [Russian Academy of Sciences, Moscow (Russian Federation). P.N. Lebedev Physical Inst.

    2009-07-01

    This book presents the Nobel Laureate Vitaly Ginzburg's views on the development in the field of superconductivity. It contains a selection of Ginzburg's key writings, including his amended version of the Nobel lecture in Physics 2003. Also included are an expanded autobiography, which was written for the Nobel Committee, an article entitled 'A Scientific Autobiography: An Attempt,' a fundamental article co-written with L.D. Landau entitled 'To the theory of superconductivity,' an expanded review article 'Superconductivity and superfluidity (what was done and what was not done),' and some newly written short articles about superconductivity and related subjects. So, in toto, presented here are the personal contributions of Ginzburg, that resulted in the Nobel Prize, in the context of his scientific biography. (orig.)

  14. Profiles of influenza A/H1N1 vaccine response using hemagglutination-inhibition titers.

    Science.gov (United States)

    Jacobson, Robert M; Grill, Diane E; Oberg, Ann L; Tosh, Pritish K; Ovsyannikova, Inna G; Poland, Gregory A

    2015-01-01

    To identify distinct antibody profiles among adults 50-to-74 years old using influenza A/H1N1 HI titers up to 75 days after vaccination. Healthy subjects 50 to 74 years old received the 2010-2011 trivalent inactivated influenza vaccine. We measured venous samples from Days 0, 28, and 75 for HI and VNA and B-cell ELISPOTs. Of 106 subjects, HI titers demonstrated a ceiling effect for 11 or 10% for those with a pre-vaccination HI titer of 1:640 where no subject post-vaccination had an increase in titer. Of the remaining 95 subjects, only 37 or 35% overall had at least a 4-fold increase by Day 28. Of these 37, 3 waned at least 4-fold, and 13 others 2-fold. Thus 15% of the subjects showed waning antibody titers by Day 75. More than half failed to respond at all. The profiles populated by these subjects as defined by HI did not vary with age or gender. The VNA results mimicked the HI profiles, but the profiles for B-cell ELISPOT did not. HI titers at Days 0, 28, and 75 populate 4 biologically plausible profiles. Limitations include lack of consensus for operationally defining waning as well as for the apparent ceiling. Furthermore, though well accepted as a marker for vaccine response, assigning thresholds with HI has limitations. However, VNA closely matches HI in populating these profiles. Thus, we hold that these profiles, having face- and content-validity, may provide a basis for understanding variation in genomic and transcriptomic response to influenza vaccination in this age group.

  15. The Implementation of Discovery Learning Model with Scientific Learning Approach to Improve Students’ Critical Thinking in Learning History

    Directory of Open Access Journals (Sweden)

    Edi Nurcahyo

    2018-03-01

    Full Text Available Historical learning has not reached optimal in the learning process. It is caused by the history teachers’ learning model has not used the innovative learning models. Furthermore, it supported by the perception of students to the history subject because it does not become final exam (UN subject so it makes less improvement and builds less critical thinking in students’ daily learning. This is due to the lack of awareness of historical events and the availability of history books for students and teachers in the library are still lacking. Discovery learning with scientific approach encourages students to solve problems actively and able to improve students' critical thinking skills with scientific approach so student can build scientific thinking include observing, asking, reasoning, trying, and networking   Keywords: discovery learning, scientific, critical thinking

  16. 2003 Scientific Technological Report; Informe Cientifico Tecnologico 2003

    Energy Technology Data Exchange (ETDEWEB)

    Prado Cuba, A; Gayoso Caballero, C; Robles Nique, A; Olivera Lescano, P [eds.

    2004-08-15

    This annual scientific-technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2003. This report includes 54 papers divided in 9 subject matters: physics and nuclear chemistry, nuclear engineering, materials science, radiochemistry, industrial applications, medical applications, environmental applications, protection and radiological safety, and management aspects.

  17. The Science of AIDS. Readings from Scientific American Magazine.

    Science.gov (United States)

    Scientific American, Inc., New York, NY.

    This collection of scientific articles on the subject of acquired immune deficiency syndrome (AIDS) covers many facets of the physical and social aspects of the disease. Technical articles deal with the molecular and cellular biology of AIDS and the Human Immunodeficiency Virus (HIV). The national and international epidemiology of AIDS and HIV are…

  18. Divergence of Scientific Heuristic Method and Direct Algebraic Instruction

    Science.gov (United States)

    Calucag, Lina S.

    2016-01-01

    This is an experimental study, made used of the non-randomized experimental and control groups, pretest-posttest designs. The experimental and control groups were two separate intact classes in Algebra. For a period of twelve sessions, the experimental group was subjected to the scientific heuristic method, but the control group instead was given…

  19. The Effectiveness of Scientific Inquiry With/Without Integration of Scientific Reasoning

    Science.gov (United States)

    Chen, Chun-Ting; She, Hsiao-Ching

    2015-01-01

    This study examines the difference in effectiveness between two scientific inquiry programs-one with an emphasis on scientific reasoning and one without a scientific reasoning component-on students' scientific concepts, scientific concept-dependent reasoning, and scientific inquiry. A mixed-method approach was used in which 115 grade 5…

  20. Forest Owners' Response to Climate Change: University Education Trumps Value Profile.

    Science.gov (United States)

    Blennow, Kristina; Persson, Johannes; Persson, Erik; Hanewinkel, Marc

    2016-01-01

    Do forest owners' levels of education or value profiles explain their responses to climate change? The cultural cognition thesis (CCT) has cast serious doubt on the familiar and often criticized "knowledge deficit" model, which says that laypeople are less concerned about climate change because they lack scientific knowledge. Advocates of CCT maintain that citizens with the highest degrees of scientific literacy and numeracy are not the most concerned about climate change. Rather, this is the group in which cultural polarization is greatest, and thus individuals with more limited scientific literacy and numeracy are more concerned about climate change under certain circumstances than those with higher scientific literacy and numeracy. The CCT predicts that cultural and other values will trump the positive effects of education on some forest owners' attitudes to climate change. Here, using survey data collected in 2010 from 766 private forest owners in Sweden and Germany, we provide the first evidence that perceptions of climate change risk are uncorrelated with, or sometimes positively correlated with, education level and can be explained without reference to cultural or other values. We conclude that the recent claim that advanced scientific literacy and numeracy polarizes perceptions of climate change risk is unsupported by the forest owner data. In neither of the two countries was university education found to reduce the perception of risk from climate change. Indeed in most cases university education increased the perception of risk. Even more importantly, the effect of university education was not dependent on the individuals' value profile.

  1. Forest Owners' Response to Climate Change: University Education Trumps Value Profile.

    Directory of Open Access Journals (Sweden)

    Kristina Blennow

    Full Text Available Do forest owners' levels of education or value profiles explain their responses to climate change? The cultural cognition thesis (CCT has cast serious doubt on the familiar and often criticized "knowledge deficit" model, which says that laypeople are less concerned about climate change because they lack scientific knowledge. Advocates of CCT maintain that citizens with the highest degrees of scientific literacy and numeracy are not the most concerned about climate change. Rather, this is the group in which cultural polarization is greatest, and thus individuals with more limited scientific literacy and numeracy are more concerned about climate change under certain circumstances than those with higher scientific literacy and numeracy. The CCT predicts that cultural and other values will trump the positive effects of education on some forest owners' attitudes to climate change. Here, using survey data collected in 2010 from 766 private forest owners in Sweden and Germany, we provide the first evidence that perceptions of climate change risk are uncorrelated with, or sometimes positively correlated with, education level and can be explained without reference to cultural or other values. We conclude that the recent claim that advanced scientific literacy and numeracy polarizes perceptions of climate change risk is unsupported by the forest owner data. In neither of the two countries was university education found to reduce the perception of risk from climate change. Indeed in most cases university education increased the perception of risk. Even more importantly, the effect of university education was not dependent on the individuals' value profile.

  2. Artificial muscles' enrichment text: Chemical Literacy Profile of pre-service teachers

    Science.gov (United States)

    Hernani, Ulum, Luthfi Lulul; Mudzakir, Ahmad

    2017-08-01

    This research aims to determine the profile of chemical literacy abilities of pre-service teachers based on scientific attitudes and scientific competencies in PISA 2015 through individualized learning by using an artificial muscle context based-enrichment book. This research uses descriptive method, involving 20 of the 90 randomly selected population. This research uses a multiple-choice questions instrument. The result of this research are : 1) in the attitude aspects of interest in science and technology, valuing scientific approaches to inquiry, and environmental awareness, the results obtained respectively for 90%, 80%, and 30%. 2) for scientific competence of apply appropriate scientific knowledge, identify models and representations, make appropriate predictions, and explain the potential implications of scientific knowledge for society, the results obtained respectively for 30%, 50%, 60%, and 55%. 3) For scientific competence of identify the question explored in a given scientific study and distinguish questions that could be investigated scientifically, the results obtained respectively for 30 % and 50%. 4) For scientific competence of transform data from one representation to another and draw appropriate conclusions, the results obtained respectively for 60% and 45%. Based on the results, which need to be developed in pre-service chemistry teachers are environmental awareness, apply appropriate scientific knowledge, identify the question explored in a given scientific study, and draw appropriate conclusions.

  3. Global artificial photosynthesis project: a scientific and legal introduction.

    Science.gov (United States)

    Faunce, Thomas

    2011-12-01

    With the global human population set to exceed 10 billion by 2050, its collective energy consumption to rise from 400 to over 500 EJ/yr and with the natural environment under increasing pressure from these sources as well as from anthropogenic climate change, political solutions such as the creation of an efficient carbon price and trading scheme may arrive too late. In this context, the scientific community is exploring technological remedies. Central to these options is artificial photosynthesis--the creation, particularly through nanotechnology, of devices capable to doing what plants have done for millions of years - transforming sunlight, water and carbon dioxide into food and fuel. This article argues that a Global Artificial Photosynthesis (GAP) project can raise the public profile and encourage the pace, complexity and funding of scientific collaborations in artificial photosynthesis research. The legal structure of a GAP project will be critical to prevent issues such as state sovereignty over energy and food resources and corporate intellectual monopoly privileges unduly inhibiting the important contribution of artificial photosynthesis to global public health and environmental sustainability. The article presents an introduction to the scientific and legal concepts behind a GAP project.

  4. Distribution of authorship in a scientific work.

    Science.gov (United States)

    Petroianu, Andy

    2012-01-01

    To publish became almost compulsory in Medicine. There is no doubt about the importance of publishing research, but the ordering of its authors is not easy. The lack of internationally accepted criteria led to the establishment of several groups or conventions particularized medical and scientific sectors. To present numerical method to establish rule of value to people who carried out the research, and whether or not incorporated as authors. The proposed score is based on the needs of each step when conducting a scientific work. They were divided into topics in which the main ones were: 1) scientific criteria for authorship; 2) create the idea that originated the work and develop hypotheses; 3) structure the method of work; 4) guiding the work; 5) write the manuscript; 6) coordinate the group that carried out the work; 7) reviewing the literature; 8) suggestions incorporated into the work; 9) to solve fundamental problems of labor; 10) to collect data; 11) presentation at scientific meetings; 12 ) lead the job and raise funds; 13) providing patients or material; 14) to do the routine needs; 15) specific fee to participate; 16) criteria for ranking the authors; 17) honorary author; 18) usurpation of the main authorship, 19) acknowledgments . It is important to emphasize that, to prevent major conflicts, the group that is willing to conduct a scientific work should establish at the outset, as objectively as possible, the criteria to be adopted for distribution of authorship. The subjective criteria here proposed avoid interference and prevent conflicts of interest.

  5. Historical knowledge and the search for truth: a reading of subjectivity and objectivity in the duality between subject and object

    Directory of Open Access Journals (Sweden)

    Fernando Tadeu Germinatti

    2018-04-01

    Full Text Available The present article presents the systematization of theoretical reflections about the debate of neutrality in the human sciences. From the presentation of the conception of scientific neutrality defended by the positivist perspective, a reflection is made on the relation between researcher and object of historical research and its imbrications to the present day. The focus is on the subjective factor and its decisive contribution to research in human science. Thus, the great epistemological richness contained in subjectivity is demonstrated. The methodology used was a bibliographical study, made from researches in classic works of historical science.

  6. DIDACTIC PRINCIPLES OF THE FORMATION OF STUDENTS’ SUBJECT POSITION

    Directory of Open Access Journals (Sweden)

    R. M. Garanina

    2017-01-01

    Full Text Available Introduction. Subject position of a personality is the phenomenon that determines self-activity, identity, sovereignty, and positive dynamics of selfdevelopment, self-education, self-training and self-realization, i.e. those qualities which are necessary for a modern expert. Therefore, the development of the concept of formation and development of a subject position of a future expert during his/her vocational training is an urgent scientific and practical task.The aim of the present research is to prove theoretically the following issues: regularities of a formation process of a subject position of a student of a higher education institution; principles reflecting features of functioning of subject space; and requirements shown to the organization of this pedagogical process.Methodology and research methods. The methods involve the analysis of philosophical and psychology and pedagogical sources on the research problem; transspective, phenomenological, psychological, comparative, system, and structure-functional types of the analysis; deductive and inductive methods; comparison, generalization, synthesis, and abstraction.Results and scientific novelty. The concept «student’s subject position» is redefined; the concept includes such features as polysystemacity, multidimensionality, and multi-functionality. The characteristics of a person with a subject position are summarized; special attention is paid to his/her personal characteristics. The regularities of formation and development of the subject position of the student caused by internal mechanisms of self-updating, self-organization, self-development and self-improvement are found out. It is testified that these regularities are shown in the system of various social relations; depend on external impact, integrity and unity of a teaching and educational process; those regularities are characterized by heterochronism, emergence, and evolving. The research enables to present an overall

  7. [Subject and pain: introduction to a philosophy of medicine].

    Science.gov (United States)

    Pérez Marc, Gonzalo

    2010-10-01

    Pain cannot be explained. It may only be understood from the most unpleasant of positions: suffering it. Thus, in the attempt to account for its multiple occurrences, meanings and mechanisms, developing a philosophy of pain appears to be essential. The approach to these issues by traditional occidental medicine has not considered the particular language in their background, which contains a double subjectivity: the subjectivity it represents itself, and that which frames the relationship between the agents where this language circulates. Articulating traditional scientific medicine with social, anthropological, and artistic disciplines would allow for a satisfactory response to this double subjectiveness, resulting in a deep change in current pain therapies.

  8. Trend Analysis of the Brazilian Scientific Production in Computer Science

    Directory of Open Access Journals (Sweden)

    TRUCOLO, C. C.

    2014-12-01

    Full Text Available The growth of scientific information volume and diversity brings new challenges in order to understand the reasons, the process and the real essence that propel this growth. This information can be used as the basis for the development of strategies and public politics to improve the education and innovation services. Trend analysis is one of the steps in this way. In this work, trend analysis of Brazilian scientific production of graduate programs in the computer science area is made to identify the main subjects being studied by these programs in general and individual ways.

  9. Algorithmic psychometrics and the scalable subject.

    Science.gov (United States)

    Stark, Luke

    2018-04-01

    Recent public controversies, ranging from the 2014 Facebook 'emotional contagion' study to psychographic data profiling by Cambridge Analytica in the 2016 American presidential election, Brexit referendum and elsewhere, signal watershed moments in which the intersecting trajectories of psychology and computer science have become matters of public concern. The entangled history of these two fields grounds the application of applied psychological techniques to digital technologies, and an investment in applying calculability to human subjectivity. Today, a quantifiable psychological subject position has been translated, via 'big data' sets and algorithmic analysis, into a model subject amenable to classification through digital media platforms. I term this position the 'scalable subject', arguing it has been shaped and made legible by algorithmic psychometrics - a broad set of affordances in digital platforms shaped by psychology and the behavioral sciences. In describing the contours of this 'scalable subject', this paper highlights the urgent need for renewed attention from STS scholars on the psy sciences, and on a computational politics attentive to psychology, emotional expression, and sociality via digital media.

  10. Scientific Technological Report 2002; Informe Cientifico Tecnologico 2002

    Energy Technology Data Exchange (ETDEWEB)

    Gayoso C, C; Cuya G, T; Robles N, A; Prado C, A [eds.

    2003-07-01

    This annual scientific-technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2002. This report includes 58 papers divided in 10 subject matters: physics and nuclear chemistry, nuclear engineering, materials, industrial applications, biological applications, medical applications, environmental applications, protection and radiological safety, nuclear safety, and management aspects.

  11. Analysis of Scientific Production in Food Science from 2003 to 2013.

    Science.gov (United States)

    Guerrero-Bote, Vicente P; Moya-Anegón, Félix

    2015-12-01

    Food Science is an active discipline in scientific research. The improvements in Food Technology constitute a challenge for society to eradicate hunger, while achieving food safety. This work analyses the scientific production in Food Science of the 25 countries with the greatest output in this subject area in the period 2003 to 2013. The growth of China's production was striking, with the country becoming top-ranked by the end of the period. Some developing countries (such as Nigeria) achieved a major increase in production but reducing their proportion of scientific collaboration and their works' impact. There appear to be 2 international collaboration networks that get good results--one European and the other Pacific. © 2015 Institute of Food Technologists®

  12. Pharmacy students' perceptions of natural science and mathematics subjects.

    Science.gov (United States)

    Prescott, Julie; Wilson, Sarah Ellen; Wan, Kai-Wai

    2014-08-15

    To determine the level of importance pharmacy students placed on science and mathematics subjects for pursuing a career in pharmacy. Two hundred fifty-four students completed a survey instrument developed to investigate students' perceptions of the relevance of science and mathematics subjects to a career in pharmacy. Pharmacy students in all 4 years of a master of pharmacy (MPharm) degree program were invited to complete the survey instrument. Students viewed chemistry-based and biology-based subjects as relevant to a pharmacy career, whereas mathematics subjects such as physics, logarithms, statistics, and algebra were not viewed important to a career in pharmacy. Students' experience in pharmacy and year of study influenced their perceptions of subjects relevant to a pharmacy career. Pharmacy educators need to consider how they can help students recognize the importance of scientific knowledge earlier in the pharmacy curriculum.

  13. Preferences of AP position of the straight Caucasian facial profile.

    Science.gov (United States)

    Mees, Steven; Jiménez Bellinga, Raúl; Mommaerts, Maurice Y; De Pauw, Guy A M

    2013-12-01

    Several investigators have compared the perception of profile attractiveness between professional and non-professional people, different groups of clinicians, and different ethnic groups. Our aim was to study preferences for facial protrusion in the lateral view for a straight Class I profile and to study the influence of gender, age, sex preference, and profession. Portrait images of one male and one female model with a Class I occlusal relationship were warped into nine different antero-posterior positions. An internet site was established to reach as many people as possible, and a request was sent by email to participate in a scientific experiment. Finally, 1707 Caucasion assessors could be grouped. The preferred male profile is the straight full ante profile. For a feminine facial profile, the straight average and the straight 2/3 ante profiles were perceived as the most attractive. Surgeons tended to give significantly higher scores to attractive (ante) profiles, which correlated strongly with scores of the orthodontists. Whenever possible with combined orthodontic/surgery treatment, straight ante profiles should be aimed for. Copyright © 2013 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  14. Prevalence, clinical profile, iron status, and subject-specific traits for excessive erythrocytosis in andean adults living permanently at 3,825 meters above sea level.

    Science.gov (United States)

    De Ferrari, Aldo; Miranda, J Jaime; Gilman, Robert H; Dávila-Román, Victor G; León-Velarde, Fabiola; Rivera-Ch, Maria; Huicho, Luis; Bernabé-Ortiz, Antonio; Wise, Robert A; Checkley, William

    2014-11-01

    Excessive erythrocytosis (EE) is a prevalent condition in populations living at high altitudes (> 2,500 m above sea level). Few large population-based studies have explored the association between EE and multiple subject-specific traits including oxygen saturation, iron status indicators, and pulmonary function. We enrolled a sex-stratified and age-stratified sample of 1,065 high-altitude residents aged ≥ 35 years from Puno, Peru (3,825 m above sea level) and conducted a standardized questionnaire and physical examination that included spirometry, pulse oximetry, and a blood sample for multiple clinical markers. Our primary objectives were to estimate the prevalence of EE, characterize the clinical profile and iron status indicators of subjects with EE, and describe subject-specific traits associated with EE. Overall prevalence of EE was 4.5% (95% CI, 3.3%-6.0%). Oxygen saturation was significantly lower among EE than non-EE group subjects (85.3% vs 90.1%, P .09 for all values). In multivariable logistic regression, we found that age ≥ 65 years (OR = 2.45, 95% CI, 1.16-5.09), male sex (3.86, 1.78-9.08), having metabolic syndrome (2.66, 1.27-5.75) or being overweight (5.20, 1.95-16.77), pulse oximetry overweight (26.7%), followed by male sex (21.5%), pulse oximetry overweight or having metabolic syndrome were associated with an important fraction of cases in our study population.

  15. A field experiment on search costs and the formation of scientific collaborations

    Czech Academy of Sciences Publication Activity Database

    Boudreau, K. J.; Brady, T.; Ganguli, I.; Gaulé, Patrick; Guinan, E.; Hollenberg, A.; Lakhani, K. R.

    2017-01-01

    Roč. 99, č. 4 (2017), s. 565-576 ISSN 0034-6535 Institutional support: RVO:67985998 Keywords : search costs * scientific collaborations Subject RIV: AH - Economics OBOR OECD: Applied Economics , Econometrics Impact factor: 2.926, year: 2016

  16. World Scientific Production in Psychology [Producción Científica de Psicología a nivel mundial

    Directory of Open Access Journals (Sweden)

    Felix de Moya-Anegón

    2012-07-01

    Full Text Available This study examines world scientific production in Psychology based on bibliometric indicators (scientific production, production’s percentage variation, average citations per document, normalized citation, impact, etc., for the period 2003–2008. The analysis is made by country, by research institutions, and scientific journals, using the Scopus (Elsevier, database of scientific literature. The results show that total world production has increased over the period studied. Four groups are acknowledge for each country, institutions, and journals, taking into account their values of scientific production, normalized citation, and subject specialization

  17. Secondary school physics teachers' conceptions of scientific evidence: A collective case study

    Science.gov (United States)

    Taylor, Joseph A.

    Engaging secondary school students in inquiry-oriented tasks that more closely simulate the scholarly activities of scientists has been recommended as a way to improve scientific literacy. Two tasks that are frequently recommended include students' design of original experiments, and students' evaluation of scientific evidence and conclusions. Yet, little is known about teachers' conceptions of experimentation. The principal aim of this study, therefore, was to describe the nature of prospective and practicing physics teachers' conceptions of scientific evidence. More specifically, the following research questions guided this study: (1) What types of issues related to the measurement reliability and experimental validity of scientific evidence do practicing and prospective physics teachers think about when designing experiments? (2) When presented with hypothetical scenarios that describe unsound experimental procedures or poorly supported conclusions (or both), what concerns will prospective and practicing physics teachers raise? And (3) When the participants' responses to parallel research prompts are compared across protocols, what similarities and differences exist? The nature of the teacher-participants' conceptions was described from an analysis of data collected from research prompts such as interviews and hand written artifacts. In these research prompts, the teachers "thought aloud" while designing experiments and critically evaluated student-collected evidence presented in hypothetical classroom scenarios. The data from this study suggested that the three teachers, while contemplating the reliability and validity of scientific evidence, frequently used their conceptions of evidence in conjunction with specific subject matter conceptions. The data also indicated that the relationship between subject matter knowledge and conceptions of evidence was more pronounced for some conceptions of evidence than for others. Suggestions for future research included

  18. Accelerating the scientific exploration process with scientific workflows

    International Nuclear Information System (INIS)

    Altintas, Ilkay; Barney, Oscar; Cheng, Zhengang; Critchlow, Terence; Ludaescher, Bertram; Parker, Steve; Shoshani, Arie; Vouk, Mladen

    2006-01-01

    Although an increasing amount of middleware has emerged in the last few years to achieve remote data access, distributed job execution, and data management, orchestrating these technologies with minimal overhead still remains a difficult task for scientists. Scientific workflow systems improve this situation by creating interfaces to a variety of technologies and automating the execution and monitoring of the workflows. Workflow systems provide domain-independent customizable interfaces and tools that combine different tools and technologies along with efficient methods for using them. As simulations and experiments move into the petascale regime, the orchestration of long running data and compute intensive tasks is becoming a major requirement for the successful steering and completion of scientific investigations. A scientific workflow is the process of combining data and processes into a configurable, structured set of steps that implement semi-automated computational solutions of a scientific problem. Kepler is a cross-project collaboration, co-founded by the SciDAC Scientific Data Management (SDM) Center, whose purpose is to develop a domain-independent scientific workflow system. It provides a workflow environment in which scientists design and execute scientific workflows by specifying the desired sequence of computational actions and the appropriate data flow, including required data transformations, between these steps. Currently deployed workflows range from local analytical pipelines to distributed, high-performance and high-throughput applications, which can be both data- and compute-intensive. The scientific workflow approach offers a number of advantages over traditional scripting-based approaches, including ease of configuration, improved reusability and maintenance of workflows and components (called actors), automated provenance management, 'smart' re-running of different versions of workflow instances, on-the-fly updateable parameters, monitoring

  19. Materials of 45. Scientific Assembly of Polish Chemical Society. Volumes 1-3

    International Nuclear Information System (INIS)

    2002-01-01

    Scientific assemblies of Polish Chemical Society are the most important chemical meeting organised annually in Poland. Basic as well as application studies in all chemical branches have been extensively presented. The next subjects was proposed as scientific sessions and symposia topics: organic chemistry, inorganic chemistry, physical chemistry, analytical chemistry, technology and chemical engineering, polymer chemistry, solid state chemistry, catalysis, biological chemistry, chemistry and technology of coal, environmental protection, didactics of chemistry, history of chemistry, young scientist forum, flow analysis, and high-energy materials

  20. ENSURING HIGH-QUALITY THEMATIC SEARCH IN THE ELECTRONIC CATALOGUE (FROM EXPERIENCE OF THE SCIENTIFIC LIBRARY OF THE ODESSA I. I. MECHNIKOV NATIONAL UNIVERSITY

    Directory of Open Access Journals (Sweden)

    Т. М. Бикова

    2015-09-01

    Full Text Available The purpose of our article is the description of electronic subject analysis of documents and creation of the dictionary of subject headings in the electronic catalog. The subject of the research is the electronic catalog of the Scientific Library of the Odessa I. I. Mechnikov National University. The purpose of work is development of a technique of edition of sections of the thesaurus. In 2012 the Scientific Library of the Odessa I. I. Mechnikov National University has moved to the new software ABIS Absotheque Unicode which allowed to improve (to simplify search in the electronic catalog. The department of scientific processing and the organization of catalogs carried out edition of sections of the thesaurus, instructions are formed, and the edition technique is developed, process of editing is studied. Drawing up the thesaurus of subject headings is carried out by means of loans from full tables BBC for scientific libraries. Even if he has no clear idea and profound knowledge of a search subject, simplifies correctly made subject headings for the reader and does more effective thematic search. The main finding of the work is in need of continuous editing subject headings that simplifies and does more comfortable search in the electronic catalog for the user of library. The research findings have the practical value for employees of libraries.

  1. A field experiment on search costs and the formation of scientific collaborations

    Czech Academy of Sciences Publication Activity Database

    Boudreau, K. J.; Brady, T.; Ganguli, I.; Gaulé, Patrick; Guinan, E.; Hollenberg, A.; Lakhani, K. R.

    2017-01-01

    Roč. 99, č. 4 (2017), s. 565-576 ISSN 0034-6535 Institutional support: Progres-Q24 Keywords : search costs * scientific collaborations Subject RIV: AH - Economics OBOR OECD: Applied Economics , Econometrics Impact factor: 2.926, year: 2016

  2. Articulated Multimedia Physics, Lesson 3, The Arithmetic of Scientific Notation.

    Science.gov (United States)

    New York Inst. of Tech., Old Westbury.

    As the third lesson of the Articulated Multimedia Physics Course, instructional materials are presented in this study guide. An introductory description is given for scientific notation methods. The subject content is provided in scrambled form, and the use of matrix transparencies is required for students to control their learning process.…

  3. Extensional scientific realism vs. intensional scientific realism.

    Science.gov (United States)

    Park, Seungbae

    2016-10-01

    Extensional scientific realism is the view that each believable scientific theory is supported by the unique first-order evidence for it and that if we want to believe that it is true, we should rely on its unique first-order evidence. In contrast, intensional scientific realism is the view that all believable scientific theories have a common feature and that we should rely on it to determine whether a theory is believable or not. Fitzpatrick argues that extensional realism is immune, while intensional realism is not, to the pessimistic induction. I reply that if extensional realism overcomes the pessimistic induction at all, that is because it implicitly relies on the theoretical resource of intensional realism. I also argue that extensional realism, by nature, cannot embed a criterion for distinguishing between believable and unbelievable theories. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Сonceptual fundamentals of a pedagogical university’s scientific research work development in the contemporary stages of society development

    Directory of Open Access Journals (Sweden)

    Alla Kolomiets

    2017-04-01

    Full Text Available Basic conceptual fundamentals of a Pedagogical University’s scientific research work organization as well as corresponding problems and assignments have been determined in the article. It’s been ascertained that some important problems remain unsettled, for instance, implementation of current scientific achievements in the contents of subject teachers’ training; popularization and marketing of scientific pedagogical achievements; intensification of scientific cooperation with foreign educational institutions; expansion of participation in joint scientific projects etc. Cardinal principals and priority directions of scientific maintenance of high-skilled teachers’ training have been defined. Practical results of a Pedagogical University’s scientific research work organization taking into consideration the determined conceptual fundamentals have been also analyzed.Key words: scientific research work monitoring, scientific activity, scientific productivity, scientific cooperation, scientific work organization, Pedagogical University.

  5. Data Transfer Advisor with Transport Profiling Optimization

    Energy Technology Data Exchange (ETDEWEB)

    Rao, Nageswara S. [ORNL; Liu, Qiang [ORNL; Yun, Daqing [Harrisburg University; Wu, Chase Qishi [New Jersey Institute of Technology; Kettimuthu, R. [Argonne National Laboratory (ANL); Jung, Eun-sung [Argonne National Laboratory (ANL)

    2017-11-01

    The network infrastructures have been rapidly upgraded in many high-performance networks (HPNs). However, such infrastructure investment has not led to corresponding performance improvement in big data transfer, especially at the application layer, largely due to the complexity of optimizing transport control on end hosts. We design and implement ProbData, a PRofiling Optimization Based DAta Transfer Advisor, to help users determine the most effective data transfer method with the most appropriate control parameter values to achieve the best data transfer performance. ProbData employs a profiling optimization based approach to exploit the optimal operational zone of various data transfer methods in support of big data transfer in extreme scale scientific applications. We present a theoretical framework of the optimized profiling approach employed in ProbData as wellas its detailed design and implementation. The advising procedure and performance benefits of ProbData are illustrated and evaluated by proof-of-concept experiments in real-life networks.

  6. Influence Cooperative Learning Method and Personality Type to Ability to Write The Scientific Article (Experiment Study on SMAN 2 Students Ciamis Learning Indonesian Subject

    Directory of Open Access Journals (Sweden)

    Supriatna Supriatna

    2017-10-01

    Full Text Available The purpose of this research was to know the influence of cooperative learning method (Jigsaw and TPS and personality type (extrovert and introvert toward students’ ability in scientific writing at the SMA Negeri 2 Ciamis class XII. The research used experimental method with 2 x 2 factorial design. The population was the students of class XII which consisted of 150. The sample was 57 students. The results showed that: (1 The ability to write scientific articles of students learning by cooperative learning method jigsaw model (= 65,88 is higher than students who learn by cooperative technique method of TPS (= 59,88, (2 Ability writing scientific articles of students whose extroverted personality (= 65.69 is higher than introverted students (= 60.06; (3 there is interaction between cooperative learning method and personality type to score of writing ability of scientific article (4 ability to write scientific article of extrovert student and studying with technique of Jigsaw (= 77,75 higher than extrovert student learning with cooperative learning method model of TPS (= 53,63 to score of writing ability of scientific article, (5 ability to write introverted student's scientific article and get treatment of cooperative learning method of jigsaw model (= 54,00 lower than introverted student learning TPS technique = 66,13, (6 the ability to write extroverted students' scientific articles studied with jigsaw techniques, and introverted students who studied Jigsaw techniques (= 77.75 were higher than those with introverted personality types studied by the Jigsaw technique (= 54.00 , (7 Ability to write scientific articles of students learning by cooperative techniques of TPS technique and have extrovert personality type ( = 53.63 lower than introverted students learning TPS techniques (= 66.13.

  7. Changes in bacterial profiles after periodontal treatment associated with respiratory quality of asthmatic children

    OpenAIRE

    Wiyarni Pambudi; Imelda Fabiola; Retno Indrawati; Haryono Utomo; Anang Endaryanto; Ariyanto Harsono

    2016-01-01

    Background Despite the reduction phenomenon of asthma exacerbation after dental plaque control, no scientific report has been found to describe the link between bacterial profiles and respiratory quality in children with asthma. Objective To investigate association between bacterial profiles changes and improvement in respiratory quality after periodontal treatment. Methods Asthmatic children with FEV1 reversibility ~ 12% and dental plaque index ~ 2 who qualified for incl...

  8. Committees for Ethics in Research involving human subjects.

    Science.gov (United States)

    Hossne, William Saad; Vieira, Sonia; De Freitas, Corina Bontempo Duca

    2008-01-01

    In Brazil since October 1996 there have been guidelines for research involving human subjects. Now human subjects know when their treatment is part of research. Deceit is no longer tolerated. But is not enough to say we offer an explanation to the potential subject and we offer a choice before he or she is confronted with an informed consent form. As in all professional activity, scientific investigation needs social controls. In Brazil, the ultimate responsibility of an investigation lies on the investigator, but in every institution where research is carried out there is a Committee for Ethics in Research. All Committees are subordinated to the National Commission of Ethics in Research, which is submitted to the Brazilian Institute of Health. During 2005 around 17,000 protocols involving 700,000 human subjects were revised by 475 Committees distributed all over the country. Approximately 7,000 people are now working in these Committees.

  9. Web User Profile Using XUL and Information Retrieval Techniques

    Directory of Open Access Journals (Sweden)

    Dan MUNTEANU

    2008-12-01

    Full Text Available This paper presents the importance of user profile in information retrieval, information filtering and recommender systems using explicit and implicit feedback. A Firefox extension (based on XUL used for gathering data needed to infer a web user profile and an example file with collected data are presented. Also an algorithm for creating and updating the user profile and keeping track of a fixed number k of subjects of interest is presented.

  10. General Critical Properties of the Dynamics of Scientific Discovery

    Energy Technology Data Exchange (ETDEWEB)

    Bettencourt, L. M. A. (LANL); Kaiser, D. I. (MIT)

    2011-05-31

    Scientific fields are difficult to define and compare, yet there is a general sense that they undergo similar stages of development. From this point of view it becomes important to determine if these superficial similarities can be translated into a general framework that would quantify the general advent and subsequent dynamics of scientific ideas. Such a framework would have important practical applications of allowing us to compare fields that superficially may appear different, in terms of their subject matter, research techniques, typical collaboration size, etc. Particularh' important in a field's history is the moment at which conceptual and technical unification allows widespread exchange of ideas and collaboration, at which point networks of collaboration show the analog of a percolation phenomenon, developing a giant connected component containing most authors. Here we investigate the generality of this topological transition in the collaboration structure of scientific fields as they grow and become denser. We develop a general theoretical framework in which each scientific field is an instantiation of the same large-scale topological critical phenomenon. We consider whether the evidence from a variety of specific fields is consistent with this picture, and estimate critical exponents associated with the transition. We then discuss the generality of the phenomenon and to what extent we may expect other scientific fields — including very large ones — to follow the same dynamics.

  11. Profile of the Brazilian scientific production in multiple sclerosis

    Directory of Open Access Journals (Sweden)

    Araujo C.R.

    2006-01-01

    Full Text Available This paper analyzes the profile of the Brazilian output in the field of multiple sclerosis from 1981 to 2004. The search was conducted through the MEDLINE and LILACS databases, selecting papers in which the term "multiple sclerosis" was defined as the main topic and "Brazil" or "Brasil" as others. The data were analyzed regarding the themes, the state in Brazil and institution where the papers were produced, the journals where the papers were published, journal's impact factor, and language. The search disclosed 141 documents (91 from MEDLINE and LILACS, and 50 from LILACS only published in 44 different journals (23 of them MEDLINE-indexed. A total of 111 documents were produced by 17 public universities, 29 by 3 private medical schools and 1 by a non-governmental organization. There were 65 original contributions, 37 case reports, 20 reviews, 6 PhD dissertations, 5 guidelines, 2 validation studies, 2 clinical trials, 2 chapters in textbooks, 1 Master of Science thesis, and 1 patient education handout. The journal impact factor ranged from 0.0217 to 6.039 (median 3.03. Of 91 papers from MEDLINE, 65 were published by Arquivos de Neuro-Psiquiatria. More than 90% of the papers were written in Portuguese. São Paulo was the most productive state in the country, followed by Rio de Janeiro, Minas Gerais and Paraná. Eighty-two percent of the Brazilian output came from the Southeastern region.

  12. Scientific and Technological Report 2004; Informe Cientifico Tecnologico 2004

    Energy Technology Data Exchange (ETDEWEB)

    Prado Cuba, Antonio; Robles Nique, Anita; Solis Veliz, Jose; Rodriguez R, Juan [eds.

    2005-08-15

    This annual scientific and technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2004. This report includes 48 papers divided in 6 subject matters, such as: materials science, nuclear engineering, industrial and environmental applications, medical and biological applications, radiation protection and nuclear safety, and management aspects.

  13. EFFECT SCIENTIFIC INQUIRY TEACHING MODELS AND SCIENTIFIC ATTITUDE TO PHYSICS STUDENT OUTCOMES

    Directory of Open Access Journals (Sweden)

    Dian Clara Natalia Sihotang

    2014-12-01

    Full Text Available The objectives of this study were to determine whether: (1 the student’s achievement taught by using Scientific Inquiry Teaching Models is better than that of taught by using Direct Instruction; (2 the student’s achievement who have a high scientific attitude is better than student who have low scientific attitude; and (3 there is interaction between Scientific Inquiry Teaching Models and scientific attitude for the student’s achievement. The results of research are: (1 the student’s achievement given learning through Scientific Inquiry Teaching Models better than Direct Instruction; (2 the student’s achievement who have a high scientific attitude better than student who have low scientific attitude; and (3 there was interaction between Scientific Inquiry Teaching Models and scientific attitude for student’s achievement which this models is better to apply for student who have a high scientific attitude.

  14. Plasma amino acid profiles are associated with insulin, C-peptide and adiponectin levels in type 2 diabetic patients

    OpenAIRE

    Nakamura, H; Jinzu, H; Nagao, K; Noguchi, Y; Shimba, N; Miyano, H; Watanabe, T; Iseki, K

    2014-01-01

    Objectives: Plasma-free amino acid (PFAA) profiles have been associated with a future risk of developing diabetes or cardiovascular disease in nondiabetic subjects. These PFAA alterations might predominantly result from the metabolic shift caused by insulin resistance and visceral fat deposition. The variety of PFAA profiles within diabetic subjects is not well researched. In this study, we focused on type 2 diabetic subjects and examined the association between PFAA profiles and insulin- and...

  15. Energy Smart Management of Scientific Data

    Energy Technology Data Exchange (ETDEWEB)

    Otoo, Ekow; Rotem, Dron; Tsao, Shih-Chiang

    2009-04-12

    Scientific data centers comprised of high-powered computing equipment and large capacity disk storage systems consume considerable amount of energy. Dynamic power management techniques (DPM) are commonly used for saving energy in disk systems. These involve powering down disks that exhibit long idle periods and placing them in standby mode. A file request from a disk in standby mode will incur both energy and performance penalties as it takes energy (and time) to spin up the disk before it can serve a file. For this reason, DPM has to make decisions as to when to transition the disk into standby mode such that the energy saved is greater than the energy needed to spin it up again and the performance penalty is tolerable. The length of the idle period until the DPM decides to power down a disk is called idlenessthreshold. In this paper, we study both analytically and experimentally dynamic power management techniques that save energy subject to performance constraints on file access costs. Based on observed workloads of scientific applications and disk characteristics, we provide a methodology for determining file assignment to disks and computing idleness thresholds that result in significant improvements to the energy saved by existing DPMsolutions while meeting response time constraints. We validate our methods with simulations that use traces taken from scientific applications.

  16. George Gamow: Scientific Amateur and Polymath

    Science.gov (United States)

    Harper, Eamon

    George Gamow (1904-1968) was among the first of the many brilliant scientists who forsook Europe for the United States in the early 1930s. Although most were fleeing the fascist imperium of Hitler and Mussolini, Gamow was one of a few who managed to escape the burgeoning despotism of Stalin in the Soviet Union. His early application of quantum mechanics to the atomic nucleus and his subsequent insight into the role played by the physics of the atom and its nucleus in stars, galaxies, and the universe identifies him as a scientist of unusual genius. Gamow displayed a boisterous, infectious - almost Rutherfordian - interest in all aspects of pure science. His interests were broad and his industry prodigious. His scientific output covered areas as diverse as nuclear physics, astrophysics, cosmology, biological genetics, and the fascinating question of the relationship of the large-scale structure and development of the universe to the properties of elementary particles and fields. He also was an immensely imaginative and prolific author of popular expositions on scientific subjects. One who is as well-known for his authorship of the Mr. Tompkins series of science popularizations as for his contributions to the development of the physical consequences of the big-bang theory of the expanding universe and the prediction of the cosmic background radiation must be unique in the scientific pantheon.

  17. The craft of scientific writing

    CERN Document Server

    Alley, Michael

    1996-01-01

    Designed to help both professional and student scientists and engineers write clearly and effectively, this text approaches the subject in a fresh way. Using scores of examples from a wide variety of authors and disciplines, the author - himself a writer and physicist -- demonstrates the difference between strong and weak scientific writing, and how to convey ideas to the intended audience. In addition, he gives advice on how to start writing, and how to revise drafts, including many suggestions about approaching a wide variety of tasks - from laboratory reports to grant proposals, from internal communications to press releases - as well as a concise guide to appropriate style and usage.

  18. Study of Scientific Problem-Solving Abilities Based on Scientific Knowledge about Atmosphere and Weather for Seventh Grade Students

    Directory of Open Access Journals (Sweden)

    Phoorin Thaengnoi

    2017-06-01

    Full Text Available The purposes of this research were: 1 to develop scientific problem-solving abilities test based on scientific knowledge about atmosphere and weather for seventh grade students and 2 to study the scientific problem-solving abilities of seventh grade students. The samples used in this study were 47 students who were studying in seventh grade in academic year 2015 of a school in Chai Nat province, Thailand. Purposive sampling was applied for identifying the samples. The research instrument of this study was the scientific problem-solving abilities test developed by the researcher. The research data was analyzed by comparing students’ scores with the criteria and considering students’ answers in each element of scientific problem-solving abilities. The results of the study were as follows: The scientific problem-solving abilities test composed of 2 parts. The first part was multiple-choice questions which was composed of 4 situations, a total of 20 questions. The Index of Item Objective Congruence of this part was varied in the range between 0.67 – 1.00. The difficulty and the discrimination level were in the range between 0.33 – 0.63 and 0.27 – 0.67, respectively. The reliability levels of this part was equal to 0.81. The second part of the test was subjective questions which composed of 2 situations, a total of 10 questions. The Index of Item Objective Congruence of this part was varied in the range between 0.67 – 1.00. The reliability level of this part was equal to 0.83. Besides, all questions in the test were covered all elements of scientific problem-solving abilities ; 1 identifying the problem 2 making the hypothesis 3 collecting data and knowledge to solve the problem 4 identifying problem-solving method and 5 predicting the characteristics of the results. The problem-solving abilities of the students revealed that 40.43% of students (n=19 were in a moderate level and 59.57% of students (n=28 were in a low level with the

  19. Profiling and sorting Mangifera Indica morphology for quality attributes and grade standards using integrated image processing algorithms

    Science.gov (United States)

    Balbin, Jessie R.; Fausto, Janette C.; Janabajab, John Michael M.; Malicdem, Daryl James L.; Marcelo, Reginald N.; Santos, Jan Jeffrey Z.

    2017-06-01

    Mango production is highly vital in the Philippines. It is very essential in the food industry as it is being used in markets and restaurants daily. The quality of mangoes can affect the income of a mango farmer, thus incorrect time of harvesting will result to loss of quality mangoes and income. Scientific farming is much needed nowadays together with new gadgets because wastage of mangoes increase annually due to uncouth quality. This research paper focuses on profiling and sorting of Mangifera Indica using image processing techniques and pattern recognition. The image of a mango is captured on a weekly basis from its early stage. In this study, the researchers monitor the growth and color transition of a mango for profiling purposes. Actual dimensions of the mango are determined through image conversion and determination of pixel and RGB values covered through MATLAB. A program is developed to determine the range of the maximum size of a standard ripe mango. Hue, light, saturation (HSL) correction is used in the filtering process to assure the exactness of RGB values of a mango subject. By pattern recognition technique, the program can determine if a mango is standard and ready to be exported.

  20. Red wine produced from the Isabella and Ives cultivar (Vitis Labrusca: profile of volatiles and aroma descriptors

    Directory of Open Access Journals (Sweden)

    Narciza Maria de Oliveira ARCANJO

    2018-03-01

    Full Text Available Abstract Considering the potential consumption and economic the importance that Isabella and Ives wines represent in the Brazilian consumer market as well as the scarcity of scientific data examining their quality, the objective of this study was to investigate the sensory quality and the volatiles profile of these wines. The volatile compounds were extracted by headspace solid-phase microextraction (HS-SPME and a total of 54 compounds were detected in red wine samples including esters (23, terpenes (12, alcohols (10, aldehydes and ketones (5 and amines (1 as well as 3 compounds belonging to other classes. Isabella and Ives red wines were sensorially characterized by 14 descriptors, through quantitative descriptive analysis (QDA. The PCAs fruity descriptors were the primary contributors to the aroma profile of the analyzed wines due to the presence of ethyl acetate and esters, especially in the wine coded as QM, which exhibited the highest variety of compounds. The differences observed in the principal components analysis, might have been influenced by the grape composition of each wine. Although the wines were from the same region, each came from a different winery and was subject to unique production processes.

  1. A profile of sports science research (1983-2003).

    Science.gov (United States)

    Williams, Stephen John; Kendall, Lawrence R

    2007-08-01

    A majority of sports science research is undertaken in universities and dedicated research centres, such as institutes of sport. Reviews of literature analysing and categorising research have been carried out, but categories identified have been limited to research design and data gathering techniques. Hence there is a need to include categories such as discipline, subjects and targeted sport. A study was conducted using document analysis method to gather data that described and categorised performance-based sports science research projects in Australian universities and institutes of sport. An instrument was designed that could be used by researchers to analyse and profile research in the area of sports science. The instrument contained six categories: targeted sport, primary study area, participant type, research setting, methodology and data gathering techniques. Research documents analysed consisted of 725 original unpublished research reports/theses. Results showed that over two-thirds of research projects were targeted to specific sports and, of this group, nearly half involved four sports: cycling, rowing, athletics and swimming. Overall, physiology was the most researched scientific discipline. The most frequently used research method was experimental design, and the most frequently used data gathering technique was physiological (performance) measures. Two-thirds of research was conducted in laboratory settings, and nearly half of the research was conducted with elite or sub-elite athletes as participants/subjects. The findings of this study provide an overall synopsis of performance-based sports science research conducted in Australia over the last 20 years, and should be of considerable importance in the ongoing development of sports science research policy in Australia.

  2. Switching Between Everyday and Scientific Language

    Science.gov (United States)

    Blown, Eric J.; Bryce, Tom G. K.

    2017-06-01

    The research reported here investigated the everyday and scientific repertoires of children involved in semi-structured, Piagetian interviews carried out to check their understanding of dynamic astronomical concepts like daytime and night-time. It focused on the switching taking place between embedded and disembedded thinking; on the imagery which subjects referred to in their verbal dialogue and their descriptions of drawings and play-dough models of the Earth, Sun and Moon; and it examined the prevalence and character of animism and figurative speech in children's thinking. Five hundred and thirty-nine children (aged 3-18) from Wairarapa in New Zealand (171 boys and 185 girls) and Changchun in China (99 boys and 84 girls) took part in the study. Modified ordinal scales for the relevant concept categories were used to classify children's responses and data from each age group (with numbers balanced as closely as practicable by culture and gender) analysed with Kolmogorov-Smirnov two-sample tests (at an alpha level of 0.05). Although, in general, there was consistency of dynamic concepts within and across media and their associated modalities in keeping with the theory of conceptual coherence (see Blown and Bryce 2010; Bryce and Blown 2016), there were several cases of inter-modal and intra-modal switching in both cultures. Qualitative data from the interview protocols revealed how children switch between everyday and scientific language (in both directions) and use imagery in response to questioning. The research indicates that children's grasp of scientific ideas in this field may ordinarily be under-estimated if one only goes by formal scientific expression and vocabulary.

  3. Theodore P. Beauchaine: award for distinguished scientific early career contributions to psychology.

    Science.gov (United States)

    2006-11-01

    Presents the citation for Theodore P. Beauchaine, who received the Award for Distinguished Scientific Early Career Contributions to Psychology (psychopathology) "for core contributions in developmental psychopathology, especially related to the biological underpinnings of various mental disorders among children, sophisticated and elegant quantitative approaches to these issues, and exemplary work on the prevention of such conditions." A brief profile and a selected bibliography accompany the citation. ((c) 2006 APA, all rights reserved).

  4. A review of scientific papers about head and neck cancers

    Energy Technology Data Exchange (ETDEWEB)

    Paoli, Severo de; Fonseca, Adenilson de Souza da; Paoli, Flavia de; Geller, Mauro [Centro Universitario Serra dos Orgaos, Teresopolis, RJ (Brazil)]. E-mail: severodepaoli@gmail.com; Presta, Giuseppe Antonio [Universidade Federal do Estado do Rio de Janeiro (UNIRIO), RJ (Brazil); Santos-Filho, Sebastiao David; Bernardo-Filho, Mario [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Inst. de Biologia Roberto Alcantara Gomes. Dept. de Biofisica e Biometria

    2008-12-15

    Head and neck cancer is one of the 10 most frequent cancers worldwide, with an estimated 500000 new cases diagnosed annually. Treatment of head and neck cancers require a multidisciplinary approach due their complexity and the functional and esthetic alterations that cancer can cause. The interest of the scientific community in a specific subject can be evaluated by analyzing of the number and the quality of published papers on the topic. The information obtained from PubMed (www.ncbi.nlm.nih.gov/sites/entrez) has been used as a tool in various publications to aid the evaluation of the scientific interest in specific research areas The aim of this work is to evaluate, using PubMed, the scientific interest in studies of head and neck cancer treatments such as radiotherapy, chemotherapy and surgery. The searches were performed on PubMed for publications from the period of 1949 to 2008 using the search terms 'head and neck cancer' and 'surgery' or 'radiotherapy' or 'chemotherapy'. The number of publications per year was determined in each search. The percentage of publications was also calculated for each subject in each year. An interest factor in a subject (IFS) was also determined. The number of publications was higher for surgery than chemotherapy or radiotherapy. The calculated 1964 IFS for surgery was 14.79, 12.74 for radiotherapy, and 19.58 for chemotherapy. The 1995 IFS for surgery was 1.99, 2.09 for radiotherapy, and 2.08 for chemotherapy. The relation obtained for 1995 was maintained in the subsequent years. There are more publications related to surgical treatment for head and neck cancer when compared with radiotherapy and chemotherapy. Moreover, in the recent years there has an increased interest in treatments utilizing chemotherapy, or this associated to radiotherapy. (author)

  5. A review of scientific papers about head and neck cancers

    International Nuclear Information System (INIS)

    Paoli, Severo de; Fonseca, Adenilson de Souza da; Paoli, Flavia de; Geller, Mauro; Presta, Giuseppe Antonio; Santos-Filho, Sebastiao David; Bernardo-Filho, Mario

    2008-01-01

    Head and neck cancer is one of the 10 most frequent cancers worldwide, with an estimated 500000 new cases diagnosed annually. Treatment of head and neck cancers require a multidisciplinary approach due their complexity and the functional and esthetic alterations that cancer can cause. The interest of the scientific community in a specific subject can be evaluated by analyzing of the number and the quality of published papers on the topic. The information obtained from PubMed (www.ncbi.nlm.nih.gov/sites/entrez) has been used as a tool in various publications to aid the evaluation of the scientific interest in specific research areas The aim of this work is to evaluate, using PubMed, the scientific interest in studies of head and neck cancer treatments such as radiotherapy, chemotherapy and surgery. The searches were performed on PubMed for publications from the period of 1949 to 2008 using the search terms 'head and neck cancer' and 'surgery' or 'radiotherapy' or 'chemotherapy'. The number of publications per year was determined in each search. The percentage of publications was also calculated for each subject in each year. An interest factor in a subject (IFS) was also determined. The number of publications was higher for surgery than chemotherapy or radiotherapy. The calculated 1964 IFS for surgery was 14.79, 12.74 for radiotherapy, and 19.58 for chemotherapy. The 1995 IFS for surgery was 1.99, 2.09 for radiotherapy, and 2.08 for chemotherapy. The relation obtained for 1995 was maintained in the subsequent years. There are more publications related to surgical treatment for head and neck cancer when compared with radiotherapy and chemotherapy. Moreover, in the recent years there has an increased interest in treatments utilizing chemotherapy, or this associated to radiotherapy. (author)

  6. Real-time PCR gene expression profiling

    Czech Academy of Sciences Publication Activity Database

    Kubista, Mikael; Sjögreen, B.; Forootan, A.; Šindelka, Radek; Jonák, Jiří; Andrade, J.M.

    2007-01-01

    Roč. 1, - (2007), s. 56-60 ISSN 1360-8606 R&D Projects: GA AV ČR KJB500520601 Institutional research plan: CEZ:AV0Z50520514 Keywords : real - time PCR, * expression profiling * statistical analysis Subject RIV: EB - Genetics ; Molecular Biology

  7. The Influence of an undergraduate scientific initiation programme onn the professional profile of new physicians

    Directory of Open Access Journals (Sweden)

    Raphael Joaquim Teles Cyrillo

    2010-09-01

    Full Text Available Introduction: This paper studies the influence of a Scientific Initiation Programme (SIP on the professional profile of new doctors from a Brazilian university. Aim and methods: Evaluate fifty-two new doctors divided into two groups matched by sex, age and academic performance and differing only in participation in the SIP. Professional and socioeconomic data were collected, including schooling of parents; average income before, during and after the medical course; current professional situation; results of exams for civil servant recruitment; and titles and degrees obtained after graduation. Results: Significant differences were found only in civil servant recruitment exam results (p = 0.0098 and in income after graduation (p = 0.02, which were both higher in the non-SIP group. Only one doctor got a M.Sc. degree after graduation, but many of them in both groups obtained technical titles, and had papers presented at congresses or published. Conclusions: Apparently, taking part in a SIP led to lower income and worse civil servant recruitment exam results. However, this may only reflect a transient phase in a long-term process. New research currently under way will answer this remaining question, now that more time has elapsed since graduation. Resumo: Introdução: Este trabalho estuda a influência de um programa de iniciação científica (PIC no perfil profissional de médicos recém-formados numa universidade pública brasileira. Objectivos e métodos: Avaliamos cinquenta e dois novos médicos arrolados em dois grupos pareados por sexo, idade e coeficiente de rendimento académico, diferindo apenas na sua participação no PIC. Dados acerca da situação profissional e socioeconómica foram obtidos, incluindo a escolaridade dos pais; a renda familiar média antes, durante e depois da realização do curso médico; a situação profissional actual; as aprovações em concurso público e os títulos e graus obtidos após a gradua

  8. State Confessional Relations: Problem of the Subject Structure

    Directory of Open Access Journals (Sweden)

    Alexandra A. Dorskaya

    2014-06-01

    Full Text Available In the article various existing definitions of the concept "state and confessional relations" are analyzed, also author's definition is offered. Three levels of the state and confessional relations are revealed: conceptual, legislative and administrative-managerial. In the article it is shown that in Russia a tradition of only two subjects of the state and confessional relations – government bodies and the religious organizations allocation exists. It is revealed that at the present stage many researchers are dissatisfied with such situation. Scientific sources of the problem of the state and church relations within the psychological school of the law, which are addressed to the personality and experiences in the legal sphere are studied and revealed. Special attention is paid to scientific heritage of the M.A. Reysner, who was one of the first to begin study of this problem. In the article the question of the school of three subjects of the state and confessional relations allocation formation, what adds the faithful or faithless personality in addition to two traditional subjects is analyzed. The state and confessional relations are considered in the context of the human rights development. The question of new type of the believer possessing high education level and knowledge formation is considered. In the article it is shown that at the present stage relations of any regulation between the state and religious organizations is based on the basis of international legal standards, domestic legislation and norms of canon law.

  9. Examining Research Questions on Germination from the Perspective of Scientific Creativity

    Science.gov (United States)

    Demir Kaçan, Sibel

    2015-01-01

    This study was conducted with the participation of 31 pre-service science teachers. Participants were asked to develop various research questions on germination. The study aims to examine research questions on the subject germination from the perspective of scientific creativity. The research questions were examined using the fluency, science…

  10. Evaluation of the toxicity and reversibility profile of the aqueous seed ...

    African Journals Online (AJOL)

    Hunteria umbellata (K. Schum.) Hallier f. (family: Apocynaceae) is reputed for the folkloric management of labour, pain and swellings, stomach ulcers, diabetes, obesity, and anaemia, with no scientific report of its toxicity and reversibility profile. The present study was, therefore, aimed at investigating the in vivo toxicity and ...

  11. Roentgenographic studies of Korean adults profile with normal occlusion

    Energy Technology Data Exchange (ETDEWEB)

    Park, Tae Won [College of Dentistry, Seoul National University, Seoul (Korea, Republic of)

    1972-11-15

    A roentgraphic cephalometric study was made on the soft and hard tissue profile of Korean adults. The subject consisted of 52 males and 54 females from 17 to 22 years of age and with normal occlusion and acceptable profile. Twenty one landmarks were plotted and two oriented lines named SnH line and SnV line were drawn on the tracings of all cephalograms. The means and the standard deviations from the subjects were calculated in each measuring category and the means were compared with those of male and female samples. The results were obtained as follow: 1. In depth and height, individual variations and sex differences of the lower facial profile were larger than the upper face. 2. The sex differences of upper facial profile were larger in height than depth. 3. The individual variations and sex differences of the top of nose were the smallest in all measuring points. 4. The thickness of the soft tissue of upper face and upper lip in male sample were larger than those of female, but the same matter were not found in mental region.

  12. A global map of science based on the ISI subject categories

    NARCIS (Netherlands)

    Leydesdorff, L.; Rafols, I

    2009-01-01

    The decomposition of scientific literature into disciplinary and subdisciplinary structures is one of the core goals of scientometrics. How can we achieve a good decomposition? The ISI subject categories classify journals included in the Science Citation Index (SCI). The aggregated journal-journal

  13. Legal and scientific scrutiny of forensic 'sciences' and 'experts'

    International Nuclear Information System (INIS)

    Metz, H.O.E.

    2002-01-01

    Full text: Traditional areas of forensic science, such as, handwriting and fingerprint examinations and the newer sciences such as molecular biology are increasingly being scrutinized and challenged by the legal and scientific communities. These older forensic disciplines are targets for critics and skeptics as they are not founded on the traditional sciences but have rather an empirical basis and are supported by what may be considered quasi-validated data. This paper discusses in broad terms the basis of these legal and scientific attitudes and the various solutions to overcoming these negative perceptions. Werner Heisenberg (1901-1976; German physicist) 'An Expert is someone who knows some of the worst mistakes that can be made in his subject and who manages to avoid them'. (author)

  14. Exploration of Korean Students' Scientific Imagination Using the Scientific Imagination Inventory

    Science.gov (United States)

    Mun, Jiyeong; Mun, Kongju; Kim, Sung-Won

    2015-01-01

    This article reports on the study of the components of scientific imagination and describes the scales used to measure scientific imagination in Korean elementary and secondary students. In this study, we developed an inventory, which we call the Scientific Imagination Inventory (SII), in order to examine aspects of scientific imagination. We…

  15. [Organization of scientific-methodological work in Central Military Clinical Hospital named after A.A. Vishnevskiĭ].

    Science.gov (United States)

    Beliakin, S A; Fokin, Iu N; Kokhan, E P; Frolkin, M N

    2009-09-01

    There was congested a wide experience of organization and management of scientific work in the 3rd CMCH by Vishnevsky A.A. for a term of more than 40 years. This experience is subjected to generalization, analyze for the purpose of determination of it's priority orientations of improvement. Scientific-methods work in hospital is rated as a complex of measures, organisationaly-planed and coordinated by purpose and reinforcement of scientific schools of the 3rd CMCH by Vishnevsky A.A., as a basis of effective delivery of specialized medical aid. The vector of scientific researches is directed, generally, to solving questions of military and field medicine.

  16. Scientific and Technological Report 2005; Informe Cientifico Tecnologico 2005

    Energy Technology Data Exchange (ETDEWEB)

    Prado Cuba, Antonio; Robles Nique, Anita; Rodriguez R, Juan; Solis Veliz, Jose [eds.

    2006-07-15

    This annual scientific and technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2005. This report includes 38 papers divided in 7 subject matters, such as: physics and chemistry, materials science, nuclear engineering, industrial and environmental applications, medical and biological applications, radiation protection and nuclear safety, and management aspects.

  17. Reproducibility of blood pressure variation in older ambulatory and bedridden subjects.

    Science.gov (United States)

    Tsuchihashi, Takuya; Kawakami, Yasunobu; Imamura, Tsuyoshi; Abe, Isao

    2002-06-01

    We investigated the influence of ambulation on the reproducibility of circadian blood pressure variation in older nursing home residents. Ambulatory blood pressure monitoring was performed twice in 37 older nursing home residents. Nursing home in Japan. Subjects included 18 ambulatory nursing home residents who had no limitation on physical activity and 19 bedridden residents who did not participate in physical activity. Twenty-four-hour, daytime, and nighttime blood pressure levels and their variability. The 24-hour and daytime variability of systolic blood pressure (SBP) was significantly greater in ambulatory than in bedridden subjects, whereas nighttime variability was similar. Significant correlations in SBP averaged for the whole day, daytime, and nighttime were observed between the two examinations in ambulatory (r =.80-.83) and bedridden (r =.83-.91) subjects, but the variabilities of SBP for the whole day and during the daytime of the first measurement were correlated with those of the second measurement in bedridden (r =.67 and r =.47, respectively) but not in ambulatory (r =.39 and r =.28, respectively) subjects. Significant correlations were found between the nocturnal SBP changes at two occasions in both ambulatory (r =.50) and bedridden (r =.51) subjects, but the dipper versus nondipper profiles, defined as reduction in SBP of greater than 10% versus not, showed low reproducibility in ambulatory subjects; five ambulatory (28%) and one bedridden (5%) subjects showed divergent profiles between the two examinations. The reproducibility of blood pressure variation in nursing home residents is influenced by ambulation.

  18. Lipid profile in ischaemic hearth disease in patients at Larkana

    International Nuclear Information System (INIS)

    Pirzado, Z.A.; Memon, A.R.; Sangi, S.A.

    1995-01-01

    The liquid profile levels in ninety six (83 males for 13 females) ischaemic heart disease (IHD) patients aged 22 to 60 years divided into elder and younger age groups with upper and low income division along with 45 control subjects matched for age and socioeconomic status were studied. Significantly elevated serum cholesterol, LDL cholesterol, triglycerides, phospholipids and total lipids as well as significantly decreased HDL-Cholesterol levels were found in IHD patients compared with control subjects. It was found that in spite of increased lipid profile with decreased HD in IHD, there was no significant difference between the upper income and low income social classes, particularly in elder patients, but the difference was significant in upper and lower social classes in normal subjects. (author)

  19. Scientific substantiation of approaches to organization and conducting radiation surveys at the rehabilitated radiation sites

    Directory of Open Access Journals (Sweden)

    I. K. Romanovich

    2017-01-01

    Full Text Available The article is concerned with the scientific justification of approaches to the organization of the final radiation survey of facilities having radioactive contamination, after their rehabilitation. Scientific publications on the previous experience in rehabilitation of facilities contaminated with radionuclides, the organization and conducting a radiation survey before the start of the decontamination, during its implementation and after its completion were analyzed. The experience in the rehabilitation of the site for the temporary storage of spent fuel and radioactive waste in Andreeva Bay in the North-West region of Russia, the locations of peaceful nuclear explosions, experimental nuclear power plants, a radiochemical laboratory, and metallurgical plants, that do not belong to radiation facilities, has been studied. It has been established that, besides the surface contamination of the soil, areas of radioactive contamination on sites of decommissioned radiation facilities with significant depth up to 15 m along the profile are available. These local zones with depth soil contamination are persistent contaminants of the groundwater. The experience in the radiation survey of the peaceful nuclear explosions sites shows the removal of radionuclides from cavities, formed with the use of nuclear explosive technologies for peaceful purposes, on the earth’s surface. An optimized list of radionuclides to be monitored during the radiological survey of rehabilitated facilities was proposed based on the analysis of the composition of radionuclides detected at radiation sites subjected to decontamination. The optimized list includes 14 radionuclides with the half-lives of more than three years. 

  20. Pattern Of Altered Lipid Profile In Patients With Subclinical And Clinical Hypothyroidism And Its Correlation With Body Mass Index

    International Nuclear Information System (INIS)

    Humerah, S.; Siddiqui, A.; Khan, H. F.

    2016-01-01

    Objective: To compare the lipid profile of the subclinical and clinical hypothyroid patients and to evaluate the correlation between body mass index (BMI) and lipid profile in hypothyroidism. Study Design: Cross-sectional study. Place and Duration of Study: Islamic International Medical College, Riphah International University, Islamabad, and Citi Laboratory, Rawalpindi, from January to December 2013. Methodology: The subjects were selected through non-probability, purposive sampling. On the basis of thyroid profile, the subjects were divided into 3 groups: euthyroids (n=20), subclinical hypothyroids (n=50), and clinical hypothyroids (n=30). The blood of these subjects was then analyzed for lipid profile. Data was analyzed using SPSS version 18 statistical software. Result: Both hypothyroid groups showed altered lipid profile which was observed to be significantly raised when compared with the euthyroid subjects. Comparison of lipid profile in euthyroid, subclinical, and clinical hypothyroid groups showed significant differences by non-parametric tests (p < 0.05). An assessment of correlation of lipid profile with the BMI was found to be significant (p < 0.01). Conclusion: Hypothyroidism causes alteration of lipid profile. Clinical and subclinical hypothyroid patients have altered lipid profile as compared to euthyroids. Thyroid status monitoring is very important, since it can induce changes in lipid profile. Such dyslipidemic status is significant not only for the management of thyroid disorders but also for common diseases like obesity and coronary atherosclerosis in the population. (author)

  1. Measuring the Subjective Well-being of Teachers

    OpenAIRE

    Rosa Isela Gluyas Fitch; Yutzil Tania Cadena Pedraza; María del Carmen Romero Sánchez; Monica Georgina Cinco Basurto

    2017-01-01

    This paper presents an instrument, designed using scientific methods, to measure the subjective well-being of teachers in relation to their work and to variables from life experience. Participant teachers work at the basic educational level in private institutions created by the civil society that attend to the needs of the socio-economically vulnerable populations outside the state’s system. The Cronbach Alfa index and exploratory factor analysis were used to establish the reliability and va...

  2. Effect of pistachio consumption on plasma lipoprotein subclasses in pre-diabetic subjects.

    Science.gov (United States)

    Hernández-Alonso, P; Salas-Salvadó, J; Baldrich-Mora, M; Mallol, R; Correig, X; Bulló, M

    2015-04-01

    Nuts have been demonstrated to improve several cardiovascular risk factors and the lipid profile in diabetic and pre-diabetic subjects. However, analysis of conventional serum lipid profiles does not completely explain the atherogenic risk associated with pre-diabetes. We therefore investigated whether chronic consumption of pistachio modifies the lipoprotein subclasses to a healthier profile in pre-diabetic subjects. Randomized cross-over clinical trial in 54 subjects with pre-diabetes. Subjects consumed a pistachio-supplemented diet (PD, 50% carbohydrates, 33% fat, including 57 g/d of pistachios daily) and a control diet (CD, 55% carbohydrates, 30% fat) for 4 months each, separated by a 2-week wash-out. Diets were isocaloric and matched for protein, fiber and saturated fatty acids. Nuclear magnetic resonance (NMR) was performed to determine changes in plasma lipoprotein subclasses. Small low-density lipoprotein particles (sLDL-P) significantly decreased after pistachio consumption compared to the nut-free diet (P = 0.023). The non-high-density lipoprotein particles (non-HDL-P i.e. VLDL-P plus LDL-P) significantly decreased under the PD compared to CD (P = 0.041). The percentage of sHDL-P increased by 2.23% after the PD compared with a reduction of 0.08% after the CD (P = 0.014). Consequently, the overall size of HDL-P significantly decreased in the PD (P = 0.007). Chronic pistachio consumption could modify the lipoprotein particle size and subclass concentrations independently of changes in total plasma lipid profile, which may help to explain the decreased risk of cardiovascular disease and mortality associated with those individuals who frequently consumed nuts. This study is registered at www.clinicaltrials.gov as NCT01441921. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. On the almost inconceivable misunderstandings concerning the subject of value-free social science.

    Science.gov (United States)

    Black, Donald

    2013-12-01

    A value judgment says what is good or bad, and value-free social science simply means social science free of value judgments. Yet many sociologists regard value-free social science as undesirable or impossible and readily make value judgments in the name of sociology. Often they display confusion about such matters as the meaning of value-free social science, value judgments internal and external to social science, value judgments as a subject of social science, the relevance of objectivity for value-free social science, and the difference between the human significance of social science and value-free social science. But why so many sociologists are so value-involved - and generally so unscientific - is sociologically understandable: The closest and most distant subjects attract the least scientific ideas. And during the past century sociologists have become increasingly close to their human subject. The debate about value-free social science is also part of an epistemological counterrevolution of humanists (including many sociologists) against the more scientific social scientists who invaded and threatened to expropriate the human subject during the past century. © London School of Economics and Political Science 2013.

  4. Genomic and Metabolomic Profile Associated to Clustering of Cardio-Metabolic Risk Factors.

    Science.gov (United States)

    Marrachelli, Vannina G; Rentero, Pilar; Mansego, María L; Morales, Jose Manuel; Galan, Inma; Pardo-Tendero, Mercedes; Martinez, Fernando; Martin-Escudero, Juan Carlos; Briongos, Laisa; Chaves, Felipe Javier; Redon, Josep; Monleon, Daniel

    2016-01-01

    To identify metabolomic and genomic markers associated with the presence of clustering of cardiometabolic risk factors (CMRFs) from a general population. One thousand five hundred and two subjects, Caucasian, > 18 years, representative of the general population, were included. Blood pressure measurement, anthropometric parameters and metabolic markers were measured. Subjects were grouped according the number of CMRFs (Group 1: profile was assessed by 1H NMR spectra using a Brucker Advance DRX 600 spectrometer. From the total population, 1217 (mean age 54±19, 50.6% men) with high genotyping call rate were analysed. A differential metabolomic profile, which included products from mitochondrial metabolism, extra mitochondrial metabolism, branched amino acids and fatty acid signals were observed among the three groups. The comparison of metabolomic patterns between subjects of Groups 1 to 3 for each of the genotypes associated to those subjects with three or more CMRFs revealed two SNPs, the rs174577_AA of FADS2 gene and the rs3803_TT of GATA2 transcription factor gene, with minimal or no statistically significant differences. Subjects with and without three or more CMRFs who shared the same genotype and metabolomic profile differed in the pattern of CMRFS cluster. Subjects of Group 3 and the AA genotype of the rs174577 had a lower prevalence of hypertension compared to the CC and CT genotype. In contrast, subjects of Group 3 and the TT genotype of the rs3803 polymorphism had a lower prevalence of T2DM, although they were predominantly males and had higher values of plasma creatinine. The results of the present study add information to the metabolomics profile and to the potential impact of genetic factors on the variants of clustering of cardiometabolic risk factors.

  5. Experience-Oriented Knowledge Organisation for the Transference of Scientific Knowledge from Universities to SMEs

    DEFF Research Database (Denmark)

    Lykke, Marianne; Løkkegaard, Sarai; Jantzen, Christian

    2018-01-01

    registered in an university research information management system. The analysis focuses on how to meet the characteristics of SMEs in the design and organisation of the subject terms in the navigation and searching system and in the presentation of the scientific knowledge. The design suggestions are based......Transferring scientific knowledge between universities and industry is known to be problematic, specifically for small and medium-sized enterprises (SMEs) that have limited resources and absorption capacity. A variety of channels is used for knowledge transfer. These include what is commonly...... referred to as generic pathways (e.g. scientific publications) and relational pathways (e.g. faculty consulting). The purpose of this research is to extend our knowledge about the design of knowledge organization for a generic pathway interface providing access to scientific knowledge and publications...

  6. 1998-2001 Scientific Technological Report; Informe Cientifico Tecnologico 1998-2001

    Energy Technology Data Exchange (ETDEWEB)

    Gayoso C, C; Ezpinoza Z, M; Prado C, A; Robles N, A [eds.

    2002-07-01

    IPEN has elaborated the 1998-2001 Scientific-Technological Report as a result of several research and development works within the fields of production and services, and related with mining, archaeology, agriculture, biology, industry and medicine as well with tracer techniques in industry, welding quality control, speed and underground waters flows, direction, water treatment, environmental pollution, geothermy, production and calibration of radioactive sources, X-rays equipment quality control, neutron physics, neutron radiography, neutron activation analysis, water traces analysis, crystal growth and building of nuclear equipment. The 1998-2001 Scientific-Technological Report includes 148 papers divided in 8 subject matters: Nuclear and Reactor Physics, Nuclear Chemistry, Nuclear Engineering, Materials, Nuclear Safety, Protection and Radiological Safety, Nuclear Applications, and Rules and Regulation.

  7. Is the subjective perception of lactose intolerance influenced by the psychological profile?

    Science.gov (United States)

    Tomba, C; Baldassarri, A; Coletta, M; Cesana, B M; Basilisco, G

    2012-10-01

    Symptoms of lactose intolerance are often attributed to lactose malabsorption but, as this relationship has not been demonstrated when a small dose of lactose similar to that contained in one cup of milk is ingested by intolerant patients, psychological factors may play a role in altered symptom perception. To assess the hypothesis that the psychological profile influences the symptoms of lactose intolerance. One hundred and two consecutive patients underwent a 15 g lactose hydrogen breath test to assess lactose malabsorption. The patients recorded the presence and severity of symptoms of lactose intolerance during the breath test using visual analogue scales. The psychological profile was assessed using a psychological symptom checklist, and health-related quality of life by means of the short-form health survey. Lactose malabsorption and intolerance were diagnosed in, respectively, 18% and 29% of the patients. The two conditions were not associated, and the severity of intolerance was even less in the patients with malabsorption. Multivariate logistic analysis showed that a high somatisation t-score was significantly associated with lactose intolerance (odds ratio 4.184; 1.704-10.309); the effects of the other psychological variables and of lactose malabsorption were not statistically significant. Health-related quality of life was significantly reduced in the patients with somatisation, but not in those with lactose malabsorption. The symptoms of lactose intolerance during hydrogen breath testing at a low physiological lactose load, are unrelated to lactose malabsorption, but may reveal a tendency towards somatisation that could impair the quality of life. © 2012 Blackwell Publishing Ltd.

  8. Educational technology: a thought about y our academic and scientific identity

    Directory of Open Access Journals (Sweden)

    Juan de PABLOS PONS

    2009-11-01

    Full Text Available The idea of this paper arises from an interesting controversy that was set off by Alan Sokal, teacher of Physics at the University of New York. This author published a paper in a very prestigious scientific journal, written in a correct language but it was completely incomprehensible. The paper was a criticism to the overvalued french postmodernists. The usefulness of an empty reasoning in the scientific world, or even the pseudo sientific jargon, was used by this author to propose the necessity of a renewal of the scientific bases of the educational technology. By considering the educational technology as a «transverse subject», in this paper the updating of some support sciences and, occasionally, the integration of new scientific foundations is proposed. All of this has to lead us towards an updating of the role of the Technology of the Education. Several aspects like the necessity of renewing the foundations of the audio visual communication, the Thinking of Systems, the Constructive Psicology and the methodological findings from the Socio Cultural Theory in designing of educational situations are considered.

  9. [The evaluation of nursing graduates' scientific reasoning and oral and written communication].

    Science.gov (United States)

    Demandes, Ingrid; Latrach, Cecilia A; Febre, Naldy Pamela; Muñoz, Claudia; Torres, Pamela; Retamal, Jessica

    2012-08-01

    This descriptive, cross-sectional study was performed in Santiago de Chile, with the objective to evaluate the scientific reasoning and the oral and written communication of nursing graduates. The sample consisted of 37 nursing graduates who participated in the three stages of the study: I) creation and validation of the instrument; II) training the faculty participating in the study to apply the instrument uniformly; and III) application of the instrument and data analysis. The data show different percentages regarding this competency, with the predominance of scientific reasoning (83.16%), followed by oral and written communication (78.37%). In conclusion, this study demonstrates the value for nursing schools to implement a formal evaluation that allows for determining the profile of nursing graduates, guaranteeing the quality of their training and education.

  10. Guidance on the scientific requirements for health claims related to gut and immune function

    DEFF Research Database (Denmark)

    Tetens, Inge

    2011-01-01

    The European Food Safety Authority (EFSA) asked the Panel on Dietetic Products Nutrition and Allergies (NDA) to draft guidance on scientific requirements for health claims related to gut and immune function. This guidance has been drawn from scientific opinions of the NDA Panel on such health......, was subjected to public consultation (28 September 2010 to 22 October 2010), and was also discussed at a technical meeting with experts in the field on 2 December 2010 in Amsterdam....

  11. [Analysis of work-related fatigue characteristics and its influencing factors in scientific and technical personnel].

    Science.gov (United States)

    Yang, Ting; Zhou, Dinglun; Song, Mingying; Lan, Yajia

    2015-02-01

    To investigate the current status and characteristics of work-related fatigue among scientific and technical personnel and its associated factors, and to provide a scientific basis for further interventions. A cross-sectional survey was conducted in the staff from a single scientific institution, using a self-administered questionnaire. Basic information of participants, Fatigue Scale-14, and Job Content Questionnaire were collected. The prevalence of work-related fatigue among the scientific and technical personnel was 54.6%; work-related fatigue was positively correlated with occupational stress (rs = 0.384, P work-related fatigue included occupational stress profiles, social support, and educational status. A higher risk of work-related fatigue was found in the staff under high stress, compared with those under low stress (OR = 8.5, 95%CI = 3.9∼18.7). Social support served as a protective factor for work-related fatigue, while a higher level of education was correlated with more severe work-related fatigue. Work-related fatigue is common and serious among scientific and technical personnel, especially in those under high stress. Effective interventions according to occupational stress are of great importance to reduce work-related fatigue.

  12. Scientific research on diseases: the distinct profile of developed and developing countries

    Energy Technology Data Exchange (ETDEWEB)

    Yegros-Yegros, A.; Rafols, I.; Abad-Garcia, M.F.; Mugnaini, R.; Meijer, I.

    2016-07-01

    In most of the countries across the globe, health is seen as a priority. The European Commission (2013), for example, considers health as a precondition for economic prosperity given that people’s health influences economic outcomes in terms of productivity, labor supply, human capital and public spending. Accordingly, the Commission places health in one of the big Societal Challenges (‘health, demographic change and wellbeing’) in Horizon 2020. Part of the investment on research and development is devoted to specific diseases. In order to assess whether scientific research is targeting the most pressing diseases, some studies have tried to analyze the degree of alignment between the funding allocated to specific diseases and the burden of disease (e.g. Gillum et al, 2011; Kingel et al, 2014). Others, like Evans et al (2014), focus on the relationship between research outputs dealing with specific diseases and the burden of disease. (Author)

  13. The Relationship between Scientific Knowledge and Behaviour: An HIV/AIDS Case

    Science.gov (United States)

    Mnguni, Lindelani; Abrie, Mia; Ebersohn, Liesel

    2016-01-01

    Debates on the role of scientific knowledge to affect behaviour are continuing. The theory of planned behaviour suggests that behaviour is influenced by attitudes, subjective norms and perceived behavioural control and not by knowledge. However, a large body of knowledge argues that increased HIV/AIDS-related knowledge leads to the adoption of…

  14. Effects of Scaffolds and Scientific Reasoning Ability on Web-Based Scientific Inquiry

    Science.gov (United States)

    Wu, Hui-Ling; Weng, Hsiao-Lan; She, Hsiao-Ching

    2016-01-01

    This study examined how background knowledge, scientific reasoning ability, and various scaffolding forms influenced students' science knowledge and scientific inquiry achievements. The students participated in an online scientific inquiry program involving such activities as generating scientific questions and drawing evidence-based conclusions,…

  15. Balance in scientific impact assessment: the EGU Awards Committe experience

    Science.gov (United States)

    Montanari, Alberto

    2016-04-01

    Evaluation of scientific impact is becoming an essential step all over the world for assigning academic positions, funding and recognition. Impact is generally assessed by means of objective bibliometric indicators which are frequently integrated with a subjective evaluation by one or more individuals. An essential requirement of impact assessment is to ensure balance across several potential discriminating factors, including gender, ethnics, culture, scientific field and many others. Scientific associations need to ensure balance in any step of their activity and in particular when electing their representatives, evaluating scientific contributions, reviewing papers and assigning awards. While ensuring balance is a strict necessity, how to get to target is still a matter of vivid debates. In fact, the context of science is very different with respect to the general context of society and the need for scientific associations to maintain confidentiality in their evaluation procedures makes the application of transparent procedures more complicated. This talk aims to present the experience and the efforts of the European Geosciences Union to ensure balance, with a particular focus on gender balance. Data and statistics will be presented in the attempt to provide constructive indications to get to the target of giving equal opportunities to researchers across gender, continents and ethnic groups. Science is a unifying discipline and balance will be vital to ensure that humans and our planet co-evolve sustainably.

  16. [Community health agents: profile and education].

    Science.gov (United States)

    Marzari, Carla Kowalski; Junges, José Roque; Selli, Lucilda

    2011-01-01

    This research discusses the profile and education of the community health agents. There is no clarity about the kind of professional needed and the appropriate training to the fulfillment of the function. The research is a case study with exploratory methodology and qualitative approach. The data was collected with a focused group, formed by ten agents, intentional selected from those with more time in service in Family Health Strategy teams from the municipality of Santa Maria, Rio Grande do Sul State. The discussions were recorded and transcribed by the researcher. The data was interpreted by content analysis. The results pointed to some important questions concerning the identity of the community health agents: integration on the health team, insertion in the community, profile and education. The profile which emerges from the research, is not different from the one proposed by the Ministry of Health. However, the difference is the professionalization, an initiative assumed by the agent, guided by reality, which he faces in his activity. The gaps, perceived in his formation, cause the agent to construct his professional identity, determined more by the technical aspect of the scientific knowledge than by his social competence as a community agent.

  17. Effects of a high-intensity intermittent training program on aerobic capacity and lipid profile in trained subjects

    Directory of Open Access Journals (Sweden)

    Ouerghi N

    2014-10-01

    cholesterol levels had decreased (by about 2% in EG1 but increased in CG. High-density lipoprotein cholesterol levels increased in EG1 and EG2, but decreased in CG. Plasma triglycerides decreased by 8% in EG1 and increased by about 4% in CG. Conclusion: Twelve weeks of short-short HIIT improves aerobic capacity. Although changes in the lipid profile were not significant after this training program, they may have a beneficial impact on health. Keywords: aerobic capacity, cholesterol, intermittent training, trained subjects, triglycerides

  18. Using Biological-Control Research in the Classroom to Promote Scientific Inquiry & Literacy

    Science.gov (United States)

    Richardson, Matthew L.; Richardson, Scott L.; Hall, David G.

    2012-01-01

    Scientists researching biological control should engage in education because translating research programs into classroom activities is a pathway to increase scientific literacy among students. Classroom activities focused on biological control target all levels of biological organization and can be cross-disciplinary by drawing from subject areas…

  19. Character profiles and life satisfaction.

    Science.gov (United States)

    Park, Hwanjin; Suh, Byung Seong; Kim, Won Sool; Lee, Hye-Kyung; Park, Seon-Cheol; Lee, Kounseok

    2015-04-01

    There is a surge of interest in subjective well-being (SWB), which concerns how individuals feel about their happiness. Life satisfaction tends to be influenced by individual psychological traits and external social factors. The aim of this study was to examine the relationship between individual character and SWB. Data from 3522 university students were analyzed in this study. Character profiles were evaluated using the Temperament and Character Inventory-Revised Short version (TCI-RS). Life satisfaction was assessed using the Satisfaction with Life Scale (SWLS). All statistical tests regarding the correlations between each character profile and life satisfaction were conducted using ANOVAs, t-tests, multiple linear regression models and correlation analyses. The creative (SCT) profile was associated with the highest levels of life satisfaction, whereas the depressive (sct) profile was associated with the lowest levels of life satisfaction. Additionally, high self-directedness, self-transcendence and cooperation were associated with high life satisfaction. The results of gender-adjusted multiple regression analysis showed that the effects of self-directedness were the strongest in the assessment of one's quality of life, followed by self-transcendence and cooperativeness, in that order. All of the three-character profiles were significantly correlated with one's quality of life, and the character profiles of TCI-RS explained 27.6% of life satisfaction in total. Among the three-character profiles, the self-directedness profile was most associated with life satisfaction. Our study was cross-sectional, and self-reported data from students at a single university were analyzed. The results of this study showed that, among the character profiles, the effects of self-directedness were the strongest for predicting life satisfaction. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. Scientists' conceptions of scientific inquiry: Revealing a private side of science

    Science.gov (United States)

    Reiff, Rebecca R.

    Science educators, philosophers, and pre-service teachers have contributed to conceptualizing inquiry but missing from the inquiry forum is an in-depth research study concerning science faculty conceptions of scientific inquiry. The science education literature has tended to focus on certain aspects of doing, teaching, and understanding scientific inquiry without linking these concepts. As a result, conceptions of scientific inquiry have been disjointed and are seemingly unrelated. Furthermore, confusion surrounding the meaning of inquiry has been identified as a reason teachers are not using inquiry in instruction (Welch et al., 1981). Part of the confusion surrounding scientific inquiry is it has been defined differently depending on the context (Colburn, 2000; Lederman, 1998; Shymansky & Yore, 1980; Wilson & Koran, 1976). This lack of a common conception of scientific inquiry is the reason for the timely nature of this research. The result of scientific journeys is not to arrive at a stopping point or the final destination, but to refuel with questions to drive the pursuit of knowledge. A three-member research team conducted Interviews with science faculty members using a semi-structured interview protocol designed to probe the subject's conceptions of scientific inquiry. The participants represented a total of 52 science faculty members from nine science departments (anthropology, biology, chemistry, geology, geography, school of health, physical education and recreation (HPER), medical sciences, physics, and school of environmental science) at a large mid-western research university. The method of analysis used by the team was grounded theory (Strauss & Corbin, 1990; Glaser & Strauss, 1967), in which case the frequency of concepts, patterns, and themes were coded to categorize scientists' conceptions of scientific inquiry. The results from this study address the following components: understanding and doing scientific inquiry, attributes of scientists engaged

  1. Initiation to scientific literacy in early years of elementary school: contributions of a didactic sequence

    Directory of Open Access Journals (Sweden)

    Juliana Pinto Viecheneski

    2013-12-01

    Full Text Available This article presents the results of a research professional, which was developed in the context of the early years of elementary school, from the application of a didactic sequence, with a view to initiation of scientific literacy of students in the literacy process of language. The methodological approach was qualitative, interpretative nature. The subjects were the students of 1st year 1st Cycle of Basic Education in a public school in Ponta Grossa - PR. The data were collected through observation, application of diagnostic testing, audio recordings, photographs, written records, illustrations and posttest. The theory History Cultural Development made the analysis of pedagogical actions and reflections on them. The main results indicate that the activities of the instructional sequence, contributed to the progressive advancement of the students' knowledge in relation to the area of science and basic scientific literacy, and also contributed to make learning the language more contextualized and interdisciplinary. It is noted that this work requires a teacher to assume the role of mediator between the scientific and the children, as well as requires the understanding that, as the subject entered the technological means, students in the early years have a right to access scientific culture. In this perspective, respecting the level of development of the children, the teacher can provide challenges and mediations necessary for the gradual construction of scientific knowledge, the first years of elementary school.

  2. Psychological and Relational Correlates of Intimate Partner Violence Profiles Among Pregnant Adolescent Couples

    Science.gov (United States)

    Lewis, Jessica B.; Sullivan, Tami P.; Angley, Meghan; Callands, Tamora; Divney, Anna A.; Magriples, Urania; Gordon, Derrick M.; Kershaw, Trace S.

    2017-01-01

    We sought to identify relationship and individual psychological factors that related to four profiles of intimate partner violence (IPV) among pregnant adolescent couples: no IPV, male IPV victim only, female IPV victim only, mutual IPV, and how associations differ by sex. Using data from a longitudinal study of pregnant adolescents and partners (n = 291 couples), we used a multivariate profile analysis using multivariate analysis of covariance with between and within-subjects effects to compare IPV groups and sex on relationship and psychological factors. Analyses were conducted at the couple level, with IPV groups as a between-subjects couple level variable and sex as a within-subjects variable that allowed us to model and compare the outcomes of both partners while controlling for the correlated nature of the data. Analyses controlled for age, race, income, relationship duration, and gestational age. Among couples, 64% had no IPV; 23% male IPV victim only; 7% mutual IPV; 5% female IPV victim only. Relationship (F = 3.61, P profile (all P profile by sex interaction (all P families from developing IPV behaviors. PMID:27135634

  3. Does fitness improve the cardiovascular risk profile in obese subjects?

    Science.gov (United States)

    Halland, H; Lønnebakken, M T; Saeed, S; Midtbø, H; Cramariuc, D; Gerdts, E

    2017-06-01

    Good cardiorespiratory fitness has been suggested to reduce the risk of cardiovascular disease in obesity. We explored the association of fitness with the prevalences of major cardiovascular risk factor like hypertension (HT), diabetes and metabolic syndrome (MetS) in overweight and obese subjects. Clinical data from 491 participants in the FAT associated CardiOvasculaR dysfunction (FATCOR) study were analyzed. Physical fitness was assessed by ergospirometry, and subjects with at least good level of performance for age and sex were classified as fit. HT subtypes were identified from clinic and 24-h ambulatory blood pressure in combination. Diabetes was diagnosed by oral glucose tolerance test. MetS was defined by the American Heart Association and National Heart, Lung and Blood Institute criteria. The participants were on average 48 years old (60% women), and mean body mass index (BMI) was 32 kg/m 2 . 28% of study participants were classified as fit. Fitness was not associated with lower prevalences of HT or HT subtypes, diabetes, MetS or individual MetS components (all p > 0.05). In multivariable regression analysis, being fit was characterized by lower waist circumference, BMI risk factors like HT, diabetes or MetS. Given the strong association of cardiovascular risk factor burden with risk of clinical cardiovascular disease, these findings challenge the notion that fitness alone is associated with lower risk of cardiovascular disease in obesity. Copyright © 2017 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

  4. The effect of nano-curcumin on HbA1c, fasting blood glucose, and lipid profile in diabetic subjects: a randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Hamid Reza Rahimi

    2016-08-01

    Full Text Available Objective: Diabetes mellitus is defined as a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both or insulin resistance. Curcumin inhibits NF-κB signaling pathway. The aim of this study is evaluation of the effect of Nano-curcumin on HbA1C, fast blood glucose and lipid profile in diabetic patients. Materials and Methods: Seventy type-2 diabetic patients (fasting blood glucose (FBG ≥ 126 mg/dL or 2-hr postprandial blood glucose ≥200 mg/dl randomly receivedeither Curcumin (as nano-micelle 80 mg/day or placebo for 3 months in a double blind randomized clinical trial. Fasting blood glucose, HbA1C, and lipids profile were checked before and after the intervention. Data analyses, including parametric and nonparametric tests were done using the SPSS 11.5 software. A p value < 0.05 was regarded as statistically significant. (RCT registration code: IRCT2013081114330N1 Results: Mean age, BMI, FBG, total cholesterol (TC, triglyceride (TG, LDL, HDL, HbA1c , and  sex and had no significant difference at the baseline between the groups. In Nano-curcumin group, a significant decrease was found in HbA1C, FBG, TG, and BMI comparing results of each subject before and after the treatment (p

  5. Bibliometric Analysis of Scientific Articles in Finance Published in FGV/SP’s The Revista de Administração de Empresas (RAE from 2006 to 2016

    Directory of Open Access Journals (Sweden)

    Rogério Martins Furtado de Souza

    2017-09-01

    Full Text Available This article aims to present the results of a study that sought to identify the profile of the scientific articles in finance published in the Revista de Administração de Empresas (RAE of the Fundação Getulio Vargas de São Paulo (FGV/SP, from 2006 to 2016, in order to contribute to the existing knowledge about the evolution of the dissemination of Brazilian scientific studies in this field. To this end, a descriptive research was performed, adopting a bibliographic and bibliometric procedure with a quantitative approach. For the organization and tabulation of the data, the MS-Excel software was used. The results showed that most of the financial articles published by RAE during the analyzed period were produced by Brazilian professionals with a doctoral degree, male, belonging to institutions in the Brazilian Southeast region, mainly FGV and USP. It was also observed that there was a great variety among the financial topics addressed, with the predominance of subjects related to the financial market and the management of big business. Corporate Governance and Capital Markets were the most published.

  6. Metabolite Profiling of Barley Grains Subjected to Water Stress: To Explain the Genotypic Difference in Drought-Induced Impacts on Malting Quality

    Directory of Open Access Journals (Sweden)

    Xiaojian Wu

    2017-09-01

    Full Text Available Grain weight and protein content will be reduced and increased, respectively, when barley is subjected to water stress after anthesis, consequently deteriorating the malt quality. However, such adverse impact of water stress differs greatly among barley genotypes. In this study, two Tibetan wild barley accessions and two cultivated varieties differing in water stress tolerance were used to investigate the genotypic difference in metabolic profiles during grain-filling stage under drought condition. Totally, 71 differently accumulated metabolites were identified, including organic acids, amino acids/amines, and sugars/sugar alcohols. Their relative contents were significantly affected by water stress for all genotypes and differed distinctly between the wild and cultivated barleys. The principal component analysis of metabolites indicated that the Tibetan wild barley XZ147 possessed a unique response to water stress. When subjected to water stress, the wild barley XZ147 showed the most increase of β-amylase activity among the four genotypes, as a result of its higher lysine content, less indole-3-acetic acid (IAA biosynthesis, more stable H2O2 homeostasis, and more up-regulation of BMY1 gene. On the other hand, XZ147 had the most reduction of β-glucan content under water stress than the other genotypes, which could be explained by the faster grain filling process and the less expression of β-glucan synthase gene GSL7. All these results indicated a great potential for XZ147 in barley breeding for improving water stress tolerance.

  7. Captain America, Tuskegee, Belmont, and Righteous Guinea Pigs: Considering Scientific Ethics through Official and Subaltern Perspectives

    Science.gov (United States)

    Weinstein, Matthew

    2008-09-01

    With an eye towards a potential scientific ethics curriculum, this paper examines four contrasting discourses regarding the ethics of using human subjects in science. The first two represent official statements regarding ethics. These include the U.S.’s National Science Education Standards, that identify ethics with a professional code, and the Belmont Report, that conceptualizes ethics in three principles to guide research oversight boards. Contrasting this view of ethics as decorum and practice in line with a priori principles is the conception of ethics from unofficial sources representing populations who have been human subjects. The first counter-discourse examined comes from Guinea Pig Zero, an underground magazine for professional human subjects. Here ethics emerges as a question of politics over principle. The good behavior of the doctors and researchers is an effect of the politics and agency of the communities that supply science with subjects. The second counter-discourse is a comic book called Truth, which tells the story of Black soldiers who were used as guinea pigs in World War II. Ethics is both more political and more uncertain in this narrative. Science is portrayed as complicit with the racism of NAZI Germany; at the same time, and in contrast to the professional guinea pigs, neither agency nor politics are presented as effective tools for forcing the ethical conduct of the scientific establishment. The conclusion examines the value of presenting all of these views of scientific ethics in science education.

  8. STUDY OF CURRENT APPROACHES FOR WEB PUBLISHING OF OPEN SCIENTIFIC DATA

    Directory of Open Access Journals (Sweden)

    D. I. Mouromtsev

    2015-11-01

    Full Text Available Subject of Study. The subject of study of this work is closely related to the development of tools and technologies for Internet publishing of open data in machine-readable formats with regard to data of universities, educational and research organizations and scientific laboratories. We analyze the trends in the publishing formats most commonly used including not only popular formats such as pdf, csv, excel, but also the Semantic Web formats such as RDF. The paper describes the way of scientific data publication in semantic formats on the example of import and convertation of the information from University database. Methods. We describe the methods of publication for scientific open data in the network consisting of a set of transformations of the original data sets to the final semantic representation. These transformation steps include data upload from a relational database, data mapping on the ontological model (schema and the generation of a set of RDF-triples corresponding to the initial database fragment. A description is given to the popular open data publishing systems, such as CKAN, VIVO, and others. OpenLink Virtuoso system is selected as the primary storage and data publication. The description of RDF data model is used as a way of presenting open data of ITMO University. Main Results. The authors have described the methods of scientific open data publication and identified their shortcomings. To demonstrate the efficiency of the proposed method of university open data publication, a software prototype has been developed available online at: http://lod.ifmo.ru/. The example of the system usage is also given. Practical Relevance. Implementation of the proposed approach will improve significantly the effect of the publication of university open data and make it available for third-party applications, such as applications for information retrieval about educational activities and research results, analysis of scientific activities in

  9. Subjective cognitive complaints included in diagnostic evaluation of dementia helps accurate diagnosis in a mixed memory clinic cohort

    DEFF Research Database (Denmark)

    Salem, L C; Vogel, Asmus Mejling; Ebstrup, J

    2015-01-01

    OBJECTIVE: Our objective was to examine the quantity and profile of subjective cognitive complaints in young patients as compared with elderly patients referred to a memory clinic. METHODS: Patients were consecutively recruited from the Copenhagen University Hospital Memory Clinic at Rigshospitalet....... In total, 307 patients and 149 age-matched healthy controls were included. Patients were classified in 4 diagnostic groups: dementia, mild cognitive impairment, affective disorders and no cognitive impairment. Subjective memory was assessed with subjective memory complaints (SMC) scale. Global cognitive...... with dementia have a significantly higher level and a different profile of subjective cognitive complaints as compared with elderly patients with dementia. Furthermore, young patients, diagnosed with an affective disorder, had the highest level of subjective cognitive complaints of all patients in a memory...

  10. From Comparison between Scientists to Gaining Cultural Scientific Knowledge: Leonardo and Galileo

    Science.gov (United States)

    Galili, Igal

    2016-01-01

    Physics textbooks often present items of disciplinary knowledge in a sequential order of topics of the theory under instruction. Such presentation is usually univocal, that is, isolated from alternative claims and contributions regarding the subject matter in the pertinent scientific discourse. We argue that comparing and contrasting the…

  11. Misadventures of education in the kingdom of psycholand: the alleged scientific support of the European Higher Education Area

    Directory of Open Access Journals (Sweden)

    José Carlos Loredo Narciandi

    2011-11-01

    Full Text Available This paper critically assesses the discourse that justifies the latest educational reforms in European and Spanish higher education. It is presented as a techno-scientific discourse that attempts to support one of the most important current practices of subjectivity -the educational one- using a particular definition of psychology that forget the fact of the irreducible plurality of psychological practices and knowledges. This paper aims thus to make a double critical assessment. On the one hand, about the rhetorical use of psycopedagogic knowledge as scientific (indisputable support for the reforms. On the other hand, about the assumption that there is a well definite discipline -psychology- which is unified, scientifically established and able to offer that support. The paper consider also the current socio-cultural scenario of globalization and neoliberalism as a context that makes sense, within the ideology of entrepreneurship, such use of psychology as a scientific guarantor of education reform. Special emphasis is placed on the promotion of subjectivity linked to that ideology, which requires individuals gifted with flexibility, self-monitoring skills and full responsibility for their fate.

  12. Meat quality and fatty acid profile of Brazilian goats subjected to different nutritional treatments.

    Science.gov (United States)

    Lopes, L S; Martins, S R; Chizzotti, M L; Busato, K C; Oliveira, I M; Machado Neto, O R; Paulino, P V R; Lanna, D P D; Ladeira, M M

    2014-08-01

    This study evaluated the effect of feed restriction and goat genotype on meat quality. Three genotypes (Brazilian native breed Canindé; Brazilian native breed Moxotó; and F1 Boer crossbred animals obtained by crossing Boer bucks with local breed does) and three different feeding regimens (ad libitum fed, AL; restricted fed at 75% of the ad libitum, R.75; or restricted fed at 50% of the average ad libitum intake, R.50) were used. There was no difference (P>0.05) in chemical composition, total and soluble collagen, and shear force of the Longissimus lumborum muscle among genotypes. However, AL had greater amounts of soluble collagen and crude protein in the muscle (P0.05) was observed for the myofibrillar fragmentation index. The goat genotype presented few differences in their fatty acid profiles. However, goats fed ad libitum had a more favorable fatty acid profile for human health with greater concentrations of oleic acid, unsaturated fatty acids, and conjugated linoleic acid. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Social sciences, scientific research, higher education and social developments - An Albanian inside of dialectics and structured scientific research, in social sciences

    Directory of Open Access Journals (Sweden)

    Nada Kallçiu

    2013-01-01

    At first this will involve the policy makers at the central level, like the Ministry of Education and Sciences and the main research actors in the public and in the private sector. The criteria of the geographical and the subjects coverage has been also used in order to be able to present a public institutions of the higher education and research but even the enterprises that act in the research area are mainly focusing to the integration of these two systems which have been working separately for a long period of time and that must become efficient in order to adapt to the conditions of a country that has limited financial resources. This article is intended to provide a comprehensive overview of the scientific research in Albania, focusing in defining the priority areas for the research in social sciences. The information about the higher education and the potential problems that it faces, is based on a big number of research institutions, selected based on their involvement in scientific research in social sciences. This article brings into evidence the fact that in order to establish a stable and effective infrastructure in scientific research in Albania, is important to work in different directions. A successful way to increase the efficasity through the elements of the “innovative system” is by working with organizations that work in specific sectors of the economy, aiming for a possible cooperation in scientific search, for an important social contribution.

  14. Competitiveness and tourism: scientific study of international production

    Directory of Open Access Journals (Sweden)

    Viviane Celina Carmona

    2014-09-01

    Full Text Available Competitiveness and tourism are becoming increasingly an emerging theme, occupying more space in the international arena, due to the growing importance of tourism as an economic sector, with several challenges and possibilities. This study aimed to identify and analyze the state of the art of the theme through the verification of the profile of international and national scientific articles published in academic journals, considering authorship, co-authorships, citations and co-citations, and social networks. In total, in the database of the Institute for Scientific Information (ISI Web of Science (WoS, 200 articles were identified, published from 1994 to 2012. Using bibliometric and sociometric techniques, it was observed that the theme gained prominence since 2008, having been published especially in tourism journals, and with the six most significant being responsible for almost 40% of the publications. Most articles are anchored in the large field of social and applied sciences and are mainly from Spain and the United States. Only five papers featured prominently in the references used by the authors, indicating the incipient nature of research in this area and the potential for development of new research.

  15. Effect of honey vinegar syrup on blood sugar and lipid profile in healthy subjects

    Directory of Open Access Journals (Sweden)

    Seyedeh-Masomeh Derakhshandeh-Rishehri

    2014-01-01

    Full Text Available Background: The impact of honey or vinegar on several metabolic abnormalities has been studied separately, a mixture of these two ingredients known as honey vinegar syrup (HVS has not been investigated previously so far. The aim of this study was to assess the impact of HVS consumption (Iranian′s traditional syrup on glycemic parameters and lipid profiles in healthy individuals. Methods: We conducted a 4-week, randomized, controlled, parallel study consisting of two groups of nonobese healthy volunteers. All subjects were asked to stay on their normal diet. Intervention group (n = 36 received a cup of HVS daily in the evening snack for 4-week (250 cc syrup contains 21.66 g honey vinegar. Assessments of fasting blood sugar (FBS, insulin, homeostasis model assessment of insulin resistance (HOMA-IR, total cholesterol (TC, triglyceride (TG, high-density lipoprotein cholesterol (HDL-C and low-density lipoprotein cholesterol (LDL-C were conducted at the baseline and after 4-week of study. Results: We observed no significant effect of HVS on FBS, HOMA-IR, LDL-C and TG. A significant effect of HVS was found on increasing fasting insulin and HOMA-IR and reduction in TC level only in intervention group (Δ =3.39 P = 0.01, Δ =1.65 P = 0.03, Δ = −9.43 P = 0.005, respectively. Changes of FBS, TG and LDL-C were 1.83 mg/dl, −1.53 mg/dl and − 3.99 mg/dl respectively in the intervention group. These changes were not significant. An unfavorable and significant reduction in HDL-C level was also observed between two groups (Δ = −4.82 P < 0.001 in the intervention group. Conclusions: Honey vinegar syrup increased fasting insulin level and decreased TC level in the intervention group. HVS had an unfavorable effect on HDL-C level. Further prospective investigations are warranted to confirm these findings.

  16. Ambulatory blood pressure and urinary albumin excretion in clinically healthy subjects

    DEFF Research Database (Denmark)

    Clausen, Peter Vilhelm; Jensen, J S; Borch-Johnsen, K

    1998-01-01

    UAER. Because 24-hour ambulatory blood pressure is a superior predictor of hypertensive target organ involvement, we aimed to investigate blood pressure profile in clinically healthy subjects with elevated UAER. Ambulatory blood pressure monitoring was performed with a portable recorder in 27 subjects...... loss of albumin could not be solely related to the higher blood pressure. In conclusion, apparently healthy subjects with elevated UAER had slightly but significantly higher 24-hour systolic and diastolic blood pressure levels in addition to increased blood pressure loads but normal circadian variation...

  17. Scientific Software - the role of best practices and recommendations

    Science.gov (United States)

    Fritzsch, Bernadette; Bernstein, Erik; Castell, Wolfgang zu; Diesmann, Markus; Haas, Holger; Hammitzsch, Martin; Konrad, Uwe; Lähnemann, David; McHardy, Alice; Pampel, Heinz; Scheliga, Kaja; Schreiber, Andreas; Steglich, Dirk

    2017-04-01

    In Geosciences - like in most other communities - scientific work strongly depends on software. For big data analysis, existing (closed or open source) program packages are often mixed with newly developed codes. Different versions of software components and varying configurations can influence the result of data analysis. This often makes reproducibility of results and reuse of codes very difficult. Policies for publication and documentation of used and newly developed software, along with best practices, can help tackle this problem. Within the Helmholtz Association a Task Group "Access to and Re-use of scientific software" was implemented by the Open Science Working Group in 2016. The aim of the Task Group is to foster the discussion about scientific software in the Open Science context and to formulate recommendations for the production and publication of scientific software, ensuring open access to it. As a first step, a workshop gathered interested scientists from institutions across Germany. The workshop brought together various existing initiatives from different scientific communities to analyse current problems, share established best practices and come up with possible solutions. The subjects in the working groups covered a broad range of themes, including technical infrastructures, standards and quality assurance, citation of software and reproducibility. Initial recommendations are presented and discussed in the talk. They are the foundation for further discussions in the Helmholtz Association and the Priority Initiative "Digital Information" of the Alliance of Science Organisations in Germany. The talk aims to inform about the activities and to link with other initiatives on the national or international level.

  18. Scientific integrity in Brazil.

    Science.gov (United States)

    Lins, Liliane; Carvalho, Fernando Martins

    2014-09-01

    This article focuses on scientific integrity and the identification of predisposing factors to scientific misconduct in Brazil. Brazilian scientific production has increased in the last ten years, but the quality of the articles has decreased. Pressure on researchers and students for increasing scientific production may contribute to scientific misconduct. Cases of misconduct in science have been recently denounced in the country. Brazil has important institutions for controlling ethical and safety aspects of human research, but there is a lack of specific offices to investigate suspected cases of misconduct and policies to deal with scientific dishonesty.

  19. Physical Profiling Performance of Air Force Primary Care Providers

    Science.gov (United States)

    2017-08-09

    AFRL-SA-WP-TR-2017-0014 Physical Profiling Performance of Air Force Primary Care Providers Anthony P. Tvaryanas1; William P...COVERED (From – To) September 2016 – January 2017 4. TITLE AND SUBTITLE Physical Profiling Performance of Air Force Primary Care Providers...encounter with their primary care team. An independent medical standards subject matter expert (SME) reviewed encounters in the electronic health record

  20. Scientific and Technological Report 2009; Informe Cientifico Tecnologico 2009

    Energy Technology Data Exchange (ETDEWEB)

    Prado Cuba, Antonio; Santiago Contreras, Julio; Lopez Milla, Alcides; Ramos Trujillo, Bertha (ed.), E-mail: aprado@ipen.gob.p [Instituto Peruano de Energia Nuclear, Lima (Peru)

    2010-11-15

    This annual scientific and technological report provides an overview of research and development activities at Peruvian Institute of Nuclear Energy (IPEN) during the period from 1 january to 31 december, 2009. This report includes 46 papers divided in 7 subject matters, such as: physics and chemistry, materials science, nuclear engineering, mining industrial and environmental applications, medical and biological applications, radiation protection and nuclear safety, and management aspects. It also includes annexes. (APC)

  1. Computer simulation, rhetoric, and the scientific imagination how virtual evidence shapes science in the making and in the news

    CERN Document Server

    Roundtree, Aimee Kendall

    2013-01-01

    Computer simulations help advance climatology, astrophysics, and other scientific disciplines. They are also at the crux of several high-profile cases of science in the news. How do simulation scientists, with little or no direct observations, make decisions about what to represent? What is the nature of simulated evidence, and how do we evaluate its strength? Aimee Kendall Roundtree suggests answers in Computer Simulation, Rhetoric, and the Scientific Imagination. She interprets simulations in the sciences by uncovering the argumentative strategies that underpin the production and disseminati

  2. Thyroid status influence on adiponectin, acylation stimulating protein (ASP and complement C3 in hyperthyroid and hypothyroid subjects

    Directory of Open Access Journals (Sweden)

    Zhang Jianhua

    2006-02-01

    Full Text Available Abstract Background Thyroid abnormalities (hyperthyroid and hypothyroid are accompanied by changes in intermediary metabolism including alterations in body weight, insulin resistance and lipid profile. The aims of this study were to examine plasma ASP, its precursor C3 and adiponectin in hyperthyroid and hypothyroid subjects as compared to controls. Methods A total of 99 subjects were recruited from endocrinology/out-patient clinics: 46 hyperthyroid subjects, 23 hypothyroid subjects and 30 control subjects. Subjects were evaluated for FT4, FT3, TSH, glucose, insulin, complete lipid profile and the adipokines: adiponectin, acylation stimulating protein (ASP and complement C3. Results Hyperthyroidism was associated with a 95% increase in adiponectin (p = 0.0002, a 47% decrease in C3 (p Conclusion These changes suggest that thyroid disease may be accompanied by changes in adipokines, which may contribute to the phenotype expressed.

  3. Scientific communication and online attention: in search of virtual colleges underpinning altmetrics data

    Directory of Open Access Journals (Sweden)

    Ronaldo Ferreira de Araújo

    2016-08-01

    Full Text Available Introduction: Informational exchanges around scientific communication activity have become increasingly dynamic in cyberspace, changing the practice of scientists and expanding the reach of research results that attain an increasingly significant online attention among different groups. Aim: To analyze whether altmetric data regarding online attention point to the existence of "virtual colleges" - composed of people from inside and outside the scientific community - around the scientific topic being discussed and shared in social media. Methodology: An exploratory pilot study, with analysis focused on the impact of the open access article with the highest altmetric indicator for the year 2015, as disclosed by Altmetric.com in its ranking "Top 100". The qualification of online attention is described by the most expressive media (Twitter and Facebook in a random sample (n = 10% on which content analysis was carried out and categorization of the types of interaction and characterization of social groups that interacted around the article. Results: The most common form of dissemination observed was retweeting on Twitter (62% and sharing on Facebook (45%, followed by "conclusive" (16% and 25% and “argumentative” (15% and 9.6% categories. The profile of the users responsible for the circulation of and discussion about the article indicates the prevalence of members from the general public. Conclusion: Altmetrics permit the tracking of the potentially more social and democratic impact assessment of scientific research, which becomes particularly evident for the case of articles featuring scientific research deemed to epitomise scientific controversies, the dimensions of which are played out in these “virtual colleges”.

  4. Bibliometric analysis about the scientific production on the Social Skills Field

    Directory of Open Access Journals (Sweden)

    Eliane Colepicolo

    2015-05-01

    Full Text Available Objective. This research consisted to contribute to the systematization of the theoretical and practical field of Social Skills, here called Social Skills Field (SSF. Method. A survey of a representative sample of CHS publications metadata extracted from the 15 scientific and technical literature databases in Psychology available in the CAPES Journals Portal was conducted. After treatment and refinement, this sample resulted in a corpus of metadata 25,409 scientific articles, which is a set of metadata publications, from fields such as author, title, subject, abstract, among others. The corpus of metadata stored in a database allowed the creation of a series of data crossing, resulting in bibliometric indicators. Results. As a result, we have: the SS Corpus, published on the Internet, which enables the inclusion of new metadata and the recovery of almost all scientific articles of the field; 2 bibliometric indicators in CHS, which may offer subsidies for the development and expansion of the field. Conclusions. Bibliometric indicators of the CHS show a representative production growth of social skills in the 1970s. Research on SS is mainly conducted by researchers from the United States, Brazil, United Kingdon and Denmark. The main subject studied are "social skills", "interpersonal relations", "social competence", "empathy", "assertividade", "assertiveness", "children", "adult", "college students"; and the major journals are: Journal of Personality and Social Psychology; Psychological Reports; Journal of Autism and Developmental Disorders and Child Development.

  5. Scientometric Analysis and Mapping of Scientific Articles on Diabetic Retinopathy.

    Science.gov (United States)

    Ramin, Shahrokh; Gharebaghi, Reza; Heidary, Fatemeh

    2015-01-01

    Diabetic retinopathy (DR) is the major cause of blindness among the working-age population globally. No systematic research has been previously performed to analyze the research published on DR, despite the need for it. This study aimed to analyze the scientific production on DR to draw overall roadmap of future research strategic planning in this field. A bibliometric method was used to obtain a view on the scientific production about DR by the data extracted from the Institute for Scientific Information (ISI). Articles about DR published in 1993-2013 were analyzed to obtain a view of the topic's structure, history, and to document relationships. The trends in the most influential publications and authors were analyzed. Most highly cited articles addressed epidemiologic and translational research topics in this field. During the past 3 years, there has been a trend toward biomarker discovery and more molecular translational research. Areas such as gene therapy and micro-RNAs are also among the recent hot topics. Through analyzing the characteristics of papers and the trends in scientific production, we performed the first scientometric report on DR. Most influential articles have addressed epidemiology and translational research subjects in this field, which reflects that globally, the earlier diagnosis and treatment of this devastating disease still has the highest global priority.

  6. Diurnal glycemic profile in obese and normal weight nondiabetic pregnant women.

    Science.gov (United States)

    Yogev, Yariv; Ben-Haroush, Avi; Chen, Rony; Rosenn, Barak; Hod, Moshe; Langer, Oded

    2004-09-01

    A paucity of data exists concerning the normal glycemic profile in nondiabetic pregnancies. Using a novel approach that provides continuous measurement of blood glucose, we sought to evaluate the ambulatory daily glycemic profile in the second half of pregnancy in nondiabetic women. Fifty-seven obese and normal weight nondiabetic subjects were evaluated for 72 consecutive hours with continuous glucose monitoring by measurement interstitial glucose levels in subcutaneous tissue every 5 minutes. Subjects were instructed not to modify their lifestyle or to follow any dietary restriction. For each woman, mean and fasting blood glucose values were determined; for each meal during the study period, the first 180 minutes were analyzed. For the study group, the fasting blood glucose level was 75 +/- 12 mg/dL; the mean blood glucose level was 83.7 +/- 18 mg/dL; the postprandial peak glucose value level was 110 +/- 16 mg/dL, and the time interval that was needed to reach peak postprandial glucose level was 70 +/- 13 minutes. A similar postprandial glycemic profile was obtained for breakfast, lunch, and dinner. Obese women were characterized by a significantly higher postprandial glucose peak value, increased 1- and 2-hour postprandial glucose levels, increased time interval for glucose peak, and significantly lower mean blood glucose during the night. No difference was found in fasting and mean blood glucose between obese and nonobese subjects. Glycemic profile characterization in both obese and normal weight nondiabetic subjects provide a measure for the desired level of glycemic control in pregnancy that is complicated with diabetes mellitus.

  7. Scientific Frontiers in the Management of Coral Reefs

    Directory of Open Access Journals (Sweden)

    Shankar eAswani

    2015-07-01

    Full Text Available Coral reefs are subjected globally to a variety of natural and anthropogenic stressors that often act synergistically. Today, reversing ongoing and future coral reef degradation presents significant challenges and countering this negative trend will take considerable efforts and investments. Scientific knowledge can inform and guide the requisite decision-making process and offer practical solutions to the problem of protection as the effects of climate change exacerbate. However, implementation of solutions presently lags far behind the pace required to reverse global declines, and there is a need for an urgent and significant step-up in the extent and range of strategies being implemented. In this paper, we consider scientific frontiers in natural and social science research that can help build stronger support for reef management and improve the efficacy of interventions. We cover various areas including: (1 enhancing the case for reef conservation and management, (2 dealing with local stressors on reefs, (3 addressing global climate change impacts, (4 and reviewing various approaches to the governance of coral reefs. In sum, we consider scientific frontiers in natural and social science that will require further attention in coming years as managers’ work towards building stronger support for reef management and improve the efficacy of local interventions.

  8. Daily consumption of banana marginally improves blood glucose and lipid profile in hypercholesterolemic subjects and increases serum adiponectin in type 2 diabetic patients.

    Science.gov (United States)

    Cressey, Ratchada; Kumsaiyai, Warunee; Mangklabruks, Ampika

    2014-12-01

    In this study, we explored the effects of consumption of banana in thirty hypercholesterolemic and fifteen type 2 diabetic subjects. They were given a daily dose of 250 or 500 grams of banana for breakfast for 12 weeks. Fasting serum lipid, glucose and insulin levels were measured initially as well as every 4 weeks. Daily consumption of banana significantly lowered fasting blood glucose (from 99 ± 7.7 to 92 ± 6.9 and 102 ± 7.3 to 92 ± 5.7 mg x dL(-1) (p profile in diabetic patients were not statistically significant, but for plasma levels of adiponectin, there were significantly increased (from 37.5 ± 9.36 to 48.8 ± 7.38 ngnml1, p consumption of banana (@ 250 g/day) is harmless both in diabetic and hypercholesterolemic volunteers and marginally beneficial to the later.

  9. Development of Scientific Approach Based on Discovery Learning Module

    Science.gov (United States)

    Ellizar, E.; Hardeli, H.; Beltris, S.; Suharni, R.

    2018-04-01

    Scientific Approach is a learning process, designed to make the students actively construct their own knowledge through stages of scientific method. The scientific approach in learning process can be done by using learning modules. One of the learning model is discovery based learning. Discovery learning is a learning model for the valuable things in learning through various activities, such as observation, experience, and reasoning. In fact, the students’ activity to construct their own knowledge were not optimal. It’s because the available learning modules were not in line with the scientific approach. The purpose of this study was to develop a scientific approach discovery based learning module on Acid Based, also on electrolyte and non-electrolyte solution. The developing process of this chemistry modules use the Plomp Model with three main stages. The stages are preliminary research, prototyping stage, and the assessment stage. The subject of this research was the 10th and 11th Grade of Senior High School students (SMAN 2 Padang). Validation were tested by the experts of Chemistry lecturers and teachers. Practicality of these modules had been tested through questionnaire. The effectiveness had been tested through experimental procedure by comparing student achievement between experiment and control groups. Based on the findings, it can be concluded that the developed scientific approach discovery based learning module significantly improve the students’ learning in Acid-based and Electrolyte solution. The result of the data analysis indicated that the chemistry module was valid in content, construct, and presentation. Chemistry module also has a good practicality level and also accordance with the available time. This chemistry module was also effective, because it can help the students to understand the content of the learning material. That’s proved by the result of learning student. Based on the result can conclude that chemistry module based on

  10. Is biotechnology a victim of anti-science bias in scientific journals?

    Science.gov (United States)

    Miller, Henry I; Morandini, Piero; Ammann, Klaus

    2008-03-01

    Primarily outside the scientific community, misapprehensions and misinformation about recombinant DNA-modified (also known as 'genetically modified', or 'GM') plants have generated significant 'pseudo-controversy' over their safety that has resulted in unscientific and excessive regulation (with attendant inflated development costs) and disappointing progress. But pseudo-controversy and sensational claims have originated within the scientific community as well, and even scholarly journals' treatment of the subject has been at times unscientific, one-sided and irresponsible. These shortcomings have helped to perpetuate 'The Big Lie' - that recombinant DNA technology applied to agriculture and food production is unproven, unsafe, untested, unregulated and unwanted. Those misconceptions, in turn, have given rise to unwarranted opposition and tortuous, distorted public policy.

  11. Role of Scientific Societies in International Collaboration

    Science.gov (United States)

    Fucugauchi, J. U.

    2007-12-01

    Geophysical research increasingly requires global multidisciplinary approaches. Understanding how deeply interrelated are Earth components and processes, population growth, increased needs of mineral and energy resources, global impact of human activities, and view of our planet as an interconnected system emphasizes the need of international cooperation. International research collaboration has an immense potential and is needed for further development of Earth science research and education. The Union Session is planned to provide a forum for analysis and discussion of the status of research and education of geosciences in developing countries, international collaboration programs and new initiatives for promoting and strengthening scientific cooperation. A theme of particular relevance in the analyses and discussions is the role of scientific societies in international collaboration. Societies organize meetings, publish journals and books and promote cooperation through academic exchange activities. They may further assist communities in developing countries in providing and facilitating access to scientific literature, attendance to international meetings, short and long-term stays and student and young researcher mobility. What else can be done? This is a complex subject and scientific societies may not be seen independently from the many factors involved in research and education. Developing countries present additional challenges resulting from limited economic resources and social and political problems, while urgently requiring improved educational and research programs. Needed are in-depth analyses of infrastructure and human resources, and identification of major problems and needs. What are the major limitations and needs in research and postgraduate education in developing countries? What and how should international collaboration do? What are the roles of individuals, academic institutions, funding agencies, scientific societies? Here we attempt to

  12. Biorepository regulatory frameworks: building parallel resources that both promote scientific investigation and protect human subjects.

    Science.gov (United States)

    Marko-Varga, György; Baker, Mark S; Boja, Emily S; Rodriguez, Henry; Fehniger, Thomas E

    2014-12-05

    Clinical samples contained in biorepositories represent an important resource for investigating the many factors that drive human biology. The biological and chemical markers contained in clinical samples provide important measures of health and disease that when combined with such medical evaluation data can aid in decision making by physicians. Nearly all disciplines in medicine and every "omic" depend upon the readouts obtained from such samples, whether the measured analyte is a gene, a protein, a lipid, or a metabolite. There are many steps in sample processing, storage, and management that need to understood by the researchers who utilize biorepositories in their own work. These include not only the preservation of the desired analytes in the sample but also good understanding of the moral and legal framework required for subject protection irrespective of where the samples have been collected. Today there is a great deal of effort in the community to align and standardize both the methodology of sample collection and storage performed in different locations and the necessary frameworks of subject protection including informed consent and institutional review of the studies being performed. There is a growing trend in developing biorepositories around the focus of large population-based studies that address both active and silent nonsymptomatic disease. Logistically these studies generate large numbers of clinical samples and practically place increasing demand upon health care systems to provide uniform sample handling, processing, storage, and documentation of both the sample and the subject as well to ensure that safeguards exist to protect the rights of the study subjects for deciding upon the fates of their samples. Currently the authority to regulate the entire scope of biorepository usage exists as national practice in law in only a few countries. Such legal protection is a necessary component within the framework of biorepositories, both now and in

  13. Serum prolactin profiles of normal human conception cycles

    Energy Technology Data Exchange (ETDEWEB)

    Adejuwon, C A [Ibadan Univ. (Nigeria). Coll. of Medicine; Faundes, Anibal [Universidade Estadual de Campinas (Brazil). Faculdade de Medicina; Segal, S J [Rockefeller Foundation, New York (USA); Alvarez-Sanchez, Francisco [Hospital Moscoso Puello, Santo Domingo (Dominican Republic). Dept. of Obstet. and Gynaecol.

    1984-06-01

    Commencing on day 10 of the menstrual cycle through onset of subsequent menses, or confirmation of pregnancy, daily sera collected from 15 women planning pregnancy were analyzed by radioimmunoassays (RIA) for prolactin (hPRL), estradiol-17..beta.. and luteinizing hormone (hLH). Two of the observed subjects became pregnant in the single cycles studied. The profiles of these hormones during the early gestation following spontaneous ovulation were established. No distinct midcycle peaks of hPEL were observed in either subject. Enormous spikes were observed in daily prolactin values, with wide variations between subjects.

  14. The psychopathic intimate partner batterer: a non-psychopathological profile

    Directory of Open Access Journals (Sweden)

    José M. Pozueco-Romero

    2014-01-01

    Full Text Available This theoretical study reviews two of the most cited profiles of intimate partner batterers in the scientific literature, paying special attention to the most notable differences between them, as well as to their common criteria. The study also discusses one of the longest standing controversies in various research studies, including the particular overview with respect to Spain: it being the constant yet erroneous reference to the equivalence of psychopathy and antisocial personality disorder. Similarly, special attention is paid to the implications of considering intimate partner batterers as having either a psychopathological or psychopathic profile, while also stressing the specific role played by psychopathy in the intimate partner batterer and, concerning psychopathic intimate partner batterers, such aspects as their specific motives for perpetrating intimate partner violence and the evaluation instruments of this particular profile. Finally, a series of future directives for research concerning psychopathic intimate partner batterers are also pointed out.

  15. Developing a scientific culture through supervision

    Directory of Open Access Journals (Sweden)

    Danie F.M. Strauss

    2012-11-01

    Full Text Available Through effective educational transmission cultural traditions are passed on to subsequent generations. The presence of alternative theoretical views of reality (paradigms in various academic disciplines uprooted the positivistic conviction that genuine science ought to be ‘objective’ and ‘neutral’. The background of this view is found in Renaissance and post-Renaissance philosophy, with its initial points of culmination in the thought of the 18th century philosopher, Immanuel Kant. He safe-guarded autonomous human freedom by restricting scholarship to phenomena (subject to the universal law of causality. The dialectic between nature and freedom gave direction to modern philosophy. Non-reductionist orientations eventually emerged recognising what is irreducible. Although a sound academic culture,operative within supervision to doctoral students, must pay attention to argumentative skills and informal logic, it must at the same time acknowledge the limitations of logic. The principle of sufficient reason refers human thinking beyond logic itself. The supervisor therefore should generate, amongst students, an awareness of the difference between reductionist and non-reductionist ontologies. Doctoral students must also realise that persistent themes and scientific revolutions go hand-in-hand. Some examples of seeing the aspects of reality as modes of explanation are given, before the seven aims of scientific endeavors identified by Stafleu are stipulated. This constitutes another important guideline that ought to be taken into account in supervising post-graduate work. Argumentative skills, scientific communication and the status of facts are discussed before a concluding formulation is given in which the overall argument of the article is summarised.

  16. Gait profile score and movement analysis profile in patients with Parkinson's disease during concurrent cognitive load

    Science.gov (United States)

    Speciali, Danielli S.; Oliveira, Elaine M.; Cardoso, Jefferson R.; Correa, João C. F.; Baker, Richard; Lucareli, Paulo R. G.

    2014-01-01

    Background: Gait disorders are common in individuals with Parkinson's Disease (PD) and the concurrent performance of motor and cognitive tasks can have marked effects on gait. The Gait Profile Score (GPS) and the Movement Analysis Profile (MAP) were developed in order to summarize the data of kinematics and facilitate understanding of the results of gait analysis. Objective: To investigate the effectiveness of the GPS and MAP in the quantification of changes in gait during a concurrent cognitive load while walking in adults with and without PD. Method: Fourteen patients with idiopathic PD and nine healthy subjects participated in the study. All subjects performed single and dual walking tasks. The GPS/MAP was computed from three-dimensional gait analysis data. Results: Differences were found between tasks for GPS (PGait Variable Score (GVS) (pelvic rotation, knee flexion-extension and ankle dorsiflexion-plantarflexion) (Pgait impairment during the dual task and suggest that GPS/MAP may be used to evaluate the effects of concurrent cognitive load while walking in patients with PD. PMID:25054382

  17. Examining subjective wellbeing and health-related quality of life in women with endometriosis.

    Science.gov (United States)

    Rush, Georgia; Misajon, RoseAnne

    2018-03-01

    The purpose of this study was to explore the subjective wellbeing, health-related quality of life and lived experience of women living with endometriosis. In 2015 five hundred participants between the ages of 18-63 (M = 30.5, SD = 7.46) were recruited through Endometriosis Australia and social media, completing an online questionnaire comprising the Personal Wellbeing Index, the Endometriosis Health Profile-30 and various open-ended questions. Results found that women with endometriosis reported low levels of subjective wellbeing (mean PWI total scores of 51.5 ± 2.03), considerably below the normative range of 70-80 for western populations. The mean Endometriosis Health Profile total score indicated a very low health-related quality of life amongst the women in this sample (78.9, ±13.14). There was also a significant relationship between scores on the Endometriosis Health Profile and Personal Wellbeing Index. The findings from the qualitative data suggest that endometriosis impacts negatively on women's lives in several areas such as; social life, relationships and future plans, this in turn affects women's overall life quality. The study highlights the strong negative impact that endometriosis can have on women's subjective wellbeing and health related quality of life, contributing to productivity issues, relationship difficulties and social dissatisfaction and increasing the risk of psychological comorbidities.

  18. Trends in scientific activity addressing transmissible spongiform encephalopathies: a bibliometric study covering the period 1973–2002

    Directory of Open Access Journals (Sweden)

    Iribarren-Maestro Isabel

    2006-10-01

    Full Text Available Abstract Background The purpose of this study is to analyse the trends in scientific research on transmissible spongiform encephalopathies by applying bibliometric tools to the scientific literature published between 1973 and 2002. Methods The data for the study were obtained from Medline database, in order to determine the volume of scientific output in the above period, the countries involved, the type of document and the trends in the subject matters addressed. The period 1973–2002 was divided in three sub-periods. Results We observed a significant growth in scientific production. The percentage of increase is 871.7 from 1973 to 2002. This is more evident since 1991 and particularly in the 1996–2001 period. The countries found to have the highest output were the United States, the United Kingdom, Japan, France and Germany. The evolution in the subject matters was almost constant in the three sub-periods in which the study was divided. In the first and second sub-periods, the subject matters of greatest interest were more general, i.e Nervous system or Nervous system diseases, Creutzfeldt-Jakob disease, Scrapie, and Chemicals and Drugs, but in the last sub-period, some changes were observed because the Prion-related matters had the greatest presence. Collaboration among authors is small from 1973 to 1992, but increases notably in the third sub-period, and also the number of authors and clusters formed. Some of the authors, like Gajdusek or Prusiner, appear in the whole period. Conclusion The study reveals a very high increase in scientific production. It is related also with the beginnings of research on bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease, with the establishment of progressive collaboration relationships and a reflection of public health concerns about this problem.

  19. Distinctive serum protein profiles involving abundant proteins in lung cancer patients based upon antibody microarray analysis

    Directory of Open Access Journals (Sweden)

    Rom William N

    2005-08-01

    Full Text Available Abstract Background Cancer serum protein profiling by mass spectrometry has uncovered mass profiles that are potentially diagnostic for several common types of cancer. However, direct mass spectrometric profiling has a limited dynamic range and difficulties in providing the identification of the distinctive proteins. We hypothesized that distinctive profiles may result from the differential expression of relatively abundant serum proteins associated with the host response. Methods Eighty-four antibodies, targeting a wide range of serum proteins, were spotted onto nitrocellulose-coated microscope slides. The abundances of the corresponding proteins were measured in 80 serum samples, from 24 newly diagnosed subjects with lung cancer, 24 healthy controls, and 32 subjects with chronic obstructive pulmonary disease (COPD. Two-color rolling-circle amplification was used to measure protein abundance. Results Seven of the 84 antibodies gave a significant difference (p Conclusion Our results suggest that a distinctive serum protein profile involving abundant proteins may be observed in lung cancer patients relative to healthy subjects or patients with chronic disease and may have utility as part of strategies for detecting lung cancer.

  20. The Revista Scientific

    Directory of Open Access Journals (Sweden)

    Oscar Antonio Martínez Molina

    2017-02-01

    Full Text Available The Revista Scientific aims to publish quality papers that include the perspective of analysis in educational settings. Together with www.indtec.com.ve, this electronic publication aims to promote and disseminate, with seriousness and rigor, the academic production in this field. Editorial of the new stage Revista Scientific was created with the aim of constituting a reference space for scientific research in the field of research analysis that is carried out within the universities in Latin America, once the distribution list hosted on the INDTEC platform (http://www.indtec.com.ve is consolidated as a space for dissemination and development of new ideas and initiatives. The first presentation of INDTEC Magazine was held in August 2016 in Venezuela. Thanks to the support of the INDTEC platform, SCIENTIFIC Magazine has been able to develop from the cooperative work of the people who make up its Editorial Committee, Academic Committee and Scientific Committee in Electronic Edition, and of the referees of each one of the numbers. Part of the success is due to the motivation of its co-editors and excellent professionals from different parts of the world: Argentina, Belgium, Colombia, Cuba, Ecuador, Spain, Mexico, Venezuela, which form the various committees, with enthusiasm and joy participating in this project (whose organizational structure is presented in this edition and continues in increcendo. Also, the strategy adopted to edit a monographic number from the various events organized in the framework of the universities, has contributed to provide SCIENTIFIC with a point value speaker of intellectual progress in the field of education. SCIENTIFIC Magazine is currently indexed in ISI, International Scientific Indexing, Dubai - UAE; ROAD, the Directory of Open Access Scholarly Resources (ISSN International Center, France; REVENCYT-ULA, Venezuela; Google Scholar (Google Scholar, International Index; Published in Calaméo; ISSUU; Academia

  1. From scientifically based research to evidence based learning

    Directory of Open Access Journals (Sweden)

    Rosa Cera

    2016-02-01

    Full Text Available This essay is a reflection on the peculiarities of the scientifically based research and on the distinctive elements of the EBL (evidence based learning, methodology used in the study on the “Relationship between Metacognition, Self-efficacy and Self-regulation in Learning”. The EBL method, based on the standardization of data, explains how the students’ learning experience can be considered as a set of “data” and can be used to explain how and when the research results can be considered generalizable and transferable to other learning situations. The reflections present in this study have also allowed us to illustrate the impact that its results have had on the micro and macro level of reality. They helped to fill in the gaps concerning the learning/teaching processes, contributed to the enrichment of the scientific literature on this subject and allowed to establish standards through rigorous techniques such as systematic reviews and meta-analysis.

  2. Single-cell gene-expression profiling and its potential diagnostic applications

    Czech Academy of Sciences Publication Activity Database

    Stahlberg, A.; Kubista, Mikael; Aman, P.

    2011-01-01

    Roč. 11, č. 7 (2011), s. 735-740 ISSN 1473-7159 R&D Projects: GA ČR(CZ) GAP303/10/1338; GA ČR(CZ) GA301/09/1752 Institutional research plan: CEZ:AV0Z50520701 Keywords : gene-expression profiling * RT-qPCR * single-cell gene-expression profiling Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.859, year: 2011

  3. Gênero e saúde: perfil e tendências da produção científica no Brasil Gender and health: profile and trends of the scientific production in Brazil

    Directory of Open Access Journals (Sweden)

    Estela M L Aquino

    2006-08-01

    have criticized this literature and offered new analythical alternatives. The present study was intended to describe the profile and trends of scientific production on gender and health in Brazil. Data sources comprised the Research Groups Directory of Conselho Nacional de Desenvolvimento Científico e Tecnológico (National Research Council, CAPES (Coordination for the Improvement of Higher Education Personnel Thesis Bank, and four journals available in SciELO - Scientific Eletronic Library Online. Fifty-one groups with at least one line of research in the subject were identified, with regional and institutional concentrations. The results confirmed the marked growth of scientific production in this field as 98 master and 42 doctoral dissertations and 665 articles on gender and health were retrieved. Women authored 86.0% and 89.0% of doctoral and master dissertations respectively, and 70.5% of the articles. Most were published in the 2000s when diversification of the studied topics was also seen. The studied subjects can be divided into five subgroups: reproduction and contraception; gender and violence; sexuality and health with emphasis on STD/AIDS; work and health, including domestic and night work; other emergent or less explored topics. There are major political, epistemological and methodological challenges for strengthening these advancements. The gender perspective offers possibilities for enlightment of theoretical dilemmas in public health. Furthermore, it can be added to other intellectual and political efforts towards understanding health and its determinants and fighting against inequalities and for social justice.

  4. SETI - A Scientific Critique and a Proposal for Further Observational Modes

    Science.gov (United States)

    Ellery, A.; Tough, A.; Darling, D.

    The Search for Extraterrestrial Intelligence (SETI) is one of the most exciting and fundamental scientific endeavours that the human race has undertaken. It falls under the banner of scientific research (unlike UFOlogy which must be classed as “pseudo-science”) but it is not clear that it follows the scientific method. Like astrobiology (also known as exobiology), it lacks a well-defined subject-matter in the form of physical evidence. However, although astrobiology is supported by a single data-set of terrestrial extremophile evidence and based upon extrapolation of physical mechanisms (life as a physico-chemical process), SETI is not. SETI is limited to a single data-point - the existence of ourselves as the sole intelligent inhabitants of Earth. To extrapolate from this is unwarranted as human intelligence is based on a unique evolutionary pathway (intelligence emerged through a contingent, historical process). We examine this problem and attempt to ascertain whether SETI is a scientific endeavour or whether it is more closely associated with other modes of human enquiry. In doing so, we review the SETI literature with an extensive bibiliography. We further suggest that the most appropriate course of action for scientific SETI is to diversify its experimental/observational techniques to resolve the Fermi paradox rather than remain reliant on the single mode of investigation currently adopted - radio astronomy.

  5. Different brain structures associated with artistic and scientific creativity: a voxel-based morphometry study.

    Science.gov (United States)

    Shi, Baoguo; Cao, Xiaoqing; Chen, Qunlin; Zhuang, Kaixiang; Qiu, Jiang

    2017-02-21

    Creativity is the ability to produce original and valuable ideas or behaviors. In real life, artistic and scientific creativity promoted the development of human civilization; however, to date, no studies have systematically investigated differences in the brain structures responsible for artistic and scientific creativity in a large sample. Using voxel-based morphometry (VBM), this study identified differences in regional gray matter volume (GMV) across the brain between artistic and scientific creativity (assessed by the Creative Achievement Questionnaire) in 356 young, healthy subjects. The results showed that artistic creativity was significantly negatively associated with the regional GMV of the supplementary motor area (SMA) and anterior cingulate cortex (ACC). In contrast, scientific creativity was significantly positively correlated with the regional GMV of the left middle frontal gyrus (MFG) and left inferior occipital gyrus (IOG). Overall, artistic creativity was associated with the salience network (SN), whereas scientific creativity was associated with the executive attention network and semantic processing. These results may provide an effective marker that can be used to predict and evaluate individuals' creative performance in the fields of science and art.

  6. Department of Civil Procedure and Formation of Its Scientific School

    Directory of Open Access Journals (Sweden)

    Вячеслав Васильович Комаров

    2016-06-01

    Full Text Available The article deals with research of the early stage of formation of scientific school of department of Civil Procedure of Yaroslav Mudryi National Law University. The achievements of the scientists of the department are analyzed, who were the intellectual founders of its scientific and pedagogical traditions. The urgent problems of civil procedure law science of that time and the scientific achievements of the department, which became cornerstones for its future development and next generations of procedural law scientists, are highlighted. The article presents the research of the subject of civil procedural law by S.Yu. Katz and L.Y. Nosko. Description of L.Y. Nosko’s works is made, in which the author examined some aspects of the method of legal regulation of civil procedure law, which at that time was innovative research direction. M.M. Vasilchenko’s research on the problem of the right to judicial protection as applied in terms of realization of the right to judicial protection by the defendant in a civil process is highlighted. Attention is drawn to the problem of theory of judicial decisions as judicial acts on implementation of the functions of justice in civil cases, particularly to T.N. Gubar’s dissertation research on this issue and to some other research works of the scientist. Yu. M. Chuikov’s position on the legal nature of a separate ruling are analyzed, which were highlighted in a monographic work of a scientist "Separate ruling in civil proceedings". In his further research, the scientist through the institute of separate ruling moves to more generalized research subject - preventive and educational activities of the court as a whole. Part of the work describes the research activities and scientific interests of A.M. Smetska, namely research on general issues on enforcement proceedings. The article also gives a brief description of the further research of the department and educational-methodical literature of the

  7. The Scientific Competitiveness of Nations.

    Science.gov (United States)

    Cimini, Giulio; Gabrielli, Andrea; Sylos Labini, Francesco

    2014-01-01

    We use citation data of scientific articles produced by individual nations in different scientific domains to determine the structure and efficiency of national research systems. We characterize the scientific fitness of each nation-that is, the competitiveness of its research system-and the complexity of each scientific domain by means of a non-linear iterative algorithm able to assess quantitatively the advantage of scientific diversification. We find that technological leading nations, beyond having the largest production of scientific papers and the largest number of citations, do not specialize in a few scientific domains. Rather, they diversify as much as possible their research system. On the other side, less developed nations are competitive only in scientific domains where also many other nations are present. Diversification thus represents the key element that correlates with scientific and technological competitiveness. A remarkable implication of this structure of the scientific competition is that the scientific domains playing the role of "markers" of national scientific competitiveness are those not necessarily of high technological requirements, but rather addressing the most "sophisticated" needs of the society.

  8. Bioinformatics Approach Based Research of Profile Protein Carbonic Anhydrase II Analysis as a Potential Candidate Cause Autism for The Variation of Learning Subjects Biotechnology

    Directory of Open Access Journals (Sweden)

    Dian Eka A. F. Ningrum

    2017-03-01

    Full Text Available This study aims to determine the needs of learning variations on Biotechnology courses using bioinformatics approaches. One example of applied use of bioinformatics in biotechnology course is the analysis of protein profiles carbonic anhydrase II as a potential cause of autism candidate. This research is a qualitative descriptive study consisted of two phases. The first phase of the data obtained from observations of learning, student questionnaires, and questionnaires lecturer. Results from the first phase, namely the need for variations learning in Biotechnology course using bioinformatics. Collecting data on the second stage uses three webserver to predict the target protein and scientific articles. Visualization of proteins using PyMOL software. 3 based webserver which is used, the candidate of target proteins associated with autism is carbonic anhydrase II. The survey results revealed that the protein carbonic anhydrase II as a potential candidate for the cause of autism classified metaloenzim are able to bind with heavy metals. The content of heavy metals in autistic patients high that affect metabolism. This prediction of protein candidate cause autism is applied use to solve the problem in society, so that can achieve the learning outcome in biotechnology course.

  9. Argumentation Quality of Socio-scientific Issue between High School Students and Postgraduate Students about Cancer

    Science.gov (United States)

    Anisa, A.; Widodo, A.; Riandi, R.

    2017-09-01

    Argumentation is one factor that can help improve critical thinking skills. Arguing means to defend statements with the various data, denials, evidence, and reinforcement that support the statement. The research aimed to capture the quality of argument skills by students in grade 12 high school students and in postgraduate student on social-scientific issues of cancer. Both group subjects are not in the same school or institution, chosen purposively with the subject of 39 high school students of grade 12 in one district of West Java and 13 students of Biology education postgraduate in one of University in West Java - Indonesia. The results of the quality structure of arguments in both subject groups show the same pattern, which is claim - warrant - and ground, with the quality of counterclaim aspects on the postgraduate students look better than grade 12 students. This provides an illustration that the ability in argumentation between students and teachers in the socio-scientific issue of cancer should be evaluate so that the learning process would be more refined in schools.

  10. Scientific Utopia: An agenda for improving scientific communication (Invited)

    Science.gov (United States)

    Nosek, B.

    2013-12-01

    The scientist's primary incentive is publication. In the present culture, open practices do not increase chances of publication, and they often require additional work. Practicing the abstract scientific values of openness and reproducibility thus requires behaviors in addition to those relevant for the primary, concrete rewards. When in conflict, concrete rewards are likely to dominate over abstract ones. As a consequence, the reward structure for scientists does not encourage openness and reproducibility. This can be changed by nudging incentives to align scientific practices with scientific values. Science will benefit by creating and connecting technologies that nudge incentives while supporting and improving the scientific workflow. For example, it should be as easy to search the research literature for my topic as it is to search the Internet to find hilarious videos of cats falling off of furniture. I will introduce the Center for Open Science (http://centerforopenscience.org/) and efforts to improve openness and reproducibility such as http://openscienceframework.org/. There will be no cats.

  11. Subjective age and personality development: a 10-year study.

    Science.gov (United States)

    Stephan, Yannick; Sutin, Angelina R; Terracciano, Antonio

    2015-04-01

    Personality theory and research typically focus on chronological age as a key indicator of personality development. This study examines whether the subjective experience of age is an alternative marker of the biomedical and psychosocial factors that contribute to individual differences in personality development. The present study uses data from the Midlife in the United States longitudinal survey (N = 3,617) to examine how subjective age is associated with stability and change in personality and the dynamic associations between subjective age and personality traits over a 10-year period. Regression analyses indicated that a younger subjective age at baseline was associated with increases in Openness, Conscientiousness, and Agreeableness; correlated changes were also found. The rank-order stability of Extraversion and Openness and overall profile consistency were higher among those with a younger subjective age at baseline and were also associated with the rate of subjective aging over time. The present study reveals that beyond chronological age, the age an individual feels is related to changes in characteristic ways of thinking, feeling, and behaving over time. © 2014 Wiley Periodicals, Inc.

  12. Lung function profiles and aerobic capacity of adult cigarette and ...

    African Journals Online (AJOL)

    Lung function profiles and aerobic capacity of adult cigarette and hookah smokers after 12 weeks intermittent training. ... All subjects performed 30 min of interval exercise (2 min of work followed by 1 min of rest) three times a week for 12 weeks at an intensity estimated at 70% of the subject's maximum aerobic capacity ...

  13. Overweight and Obesity, Lipid Profile and Atherogenic Indices ...

    African Journals Online (AJOL)

    Male subjects were found to have more favorable plasma lipid profile (lower LDL. ... C) than the females. ... social habits with a low level of physical activity, which may predispose them ... greater physical activity and regular medical check.up.

  14. The biologic effects of grounding the human body during sleep as measured by cortisol levels and subjective reporting of sleep, pain, and stress.

    Science.gov (United States)

    Ghaly, Maurice; Teplitz, Dale

    2004-10-01

    Diurnal cortisol secretion levels were measured and circadian cortisol profiles were evaluated in a pilot study conducted to test the hypothesis that grounding the human body to earth during sleep will result in quantifiable changes in cortisol. It was also hypothesized that grounding the human body would result in changes in sleep, pain, and stress (anxiety, depression, irritability), as measured by subjective reporting. Twelve (12) subjects with complaints of sleep dysfunction, pain, and stress were grounded to earth during sleep for 8 weeks in their own beds using a conductive mattress pad. Saliva tests were administered to establish pregrounding baseline cortisol levels. Levels were obtained at 4-hour intervals for a 24-hour period to determine the circadian cortisol profile. Cortisol testing was repeated at week 6. Subjective symptoms of sleep dysfunction, pain, and stress were reported daily throughout the 8-week test period. Measurable improvements in diurnal cortisol profiles were observed, with cortisol levels significantly reduced during night-time sleep. Subjects' 24-hour circadian cortisol profiles showed a trend toward normalization. Subjectively reported symptoms, including sleep dysfunction, pain, and stress, were reduced or eliminated in nearly all subjects. Results indicate that grounding the human body to earth ("earthing") during sleep reduces night-time levels of cortisol and resynchronizes cortisol hormone secretion more in alignment with the natural 24-hour circadian rhythm profile. Changes were most apparent in females. Furthermore, subjective reporting indicates that grounding the human body to earth during sleep improves sleep and reduces pain and stress.

  15. Компьютеризированный программно-методический комплекс по дисциплине «Автоматическое управление электроприводами»

    OpenAIRE

    Шрейнер, Р. Т.; Сорокина, В. Е.; Окуловская, А. Г.; Гомзиков, А. Л.

    1997-01-01

    Results of the scientific-investigation work «The computer-aided technologies of professional pedagogical staff training, profiling on electroenergetics» are being listed. The problems of the software and methodical supply of the profiling subject «Automatic control of the electric drives» are being discussed

  16. Profiles of Information Consumption and Production of CIEMAT Researches within the Period 2005-2007

    International Nuclear Information System (INIS)

    Sanz, C.

    2010-01-01

    Given the importance of scientific and technological evaluation in the current international scene, the goal is to show CIEMAT researchers' profiles on information consumption and production through different biblio metric indicators, mainly quantitative. Taking further steps based on this data, margins of coincidence on both patterns will be carefully checked not only from a group perspective but also on an individual scale, in the most widely used scientific journals. This analysis shall reveal the information needs of researchers for the future design of documentary strategies. (Author) 21 refs.

  17. Shaping scientific attitude of biology education students through research-based teaching

    Science.gov (United States)

    Firdaus, Darmadi

    2017-08-01

    Scientific attitude is need of today's society for peaceful and meaningful living of every person in a multicultural world. A case study was conducted at the Faculty of Teacher Training and Education, University of Riau, Pekanbaru in order to describe the scientific attitude that shaped by research-based teaching (RBT). Eighteen students of English for Biology bilingual program were selected from 88 regular students as a subject of the study. RBT designed consists of 9 steps: 1) field observations, 2) developing research proposals, 3) research proposal seminar, 4) field data collecting, 5) data analyzing & ilustrating, 6) writing research papers, 7) preparing power point slides, 8) creating a scientific poster, 9) seminar & poster session. Data were collected by using check list observation instuments during 14 weeks (course sessions), then analyzed by using descriptive-quantitative method. The results showed that RBT were able to shape critical-mindedness, suspended judgement, respect for evidence, honesty, objectivity, and questioning attitude as well as tolerance of uncertainty. These attitudes which shaped were varies according to every steps of learning activities. It's seems that the preparation of scientific posters and research seminar quite good in shaping the critical-mindedness, suspended judgment, respect for evidence, honesty, objectivity, and questioning attitude, as well as tolerance of uncertainty. In conclusion, the application of research-based teaching through the English for Biology courses could shape the students scientific attitudes. However, the consistency of the appearance of a scientific attitude in every stage of Biology-based RBT learning process need more intensive and critical assessment.

  18. Scientific issues in fuel behaviour

    International Nuclear Information System (INIS)

    1995-01-01

    The current limits on discharge burnup in today's nuclear power stations have proven the fuel to be very reliable in its performance, with a negligibly small rate of failure. However, for reasons of economy, there are moves to increase the fuel enrichment in order to extend both the cycle time and the discharge burnup. But, longer periods of irradiation cause increased microstructural changes in the fuel and cladding, implying a larger degradation of physical and mechanical properties. This degradation may well limit the plant life, hence the NSC concluded that it is of importance to develop a predictive capability of fuel behaviour at extended burnup. This can only be achieved through an improved understanding of the basic underlying phenomena of fuel behaviour. The Task Force on Scientific Issues Related to Fuel Behaviour of the NEA Nuclear Science Committee has identified the most important scientific issues on the subject and has assigned priorities. Modelling aspects are listed in Appendix A and discussed in Part II. In addition, quality assurance process for performing and evaluating new integral experiments is considered of special importance. Main activities on fuel behaviour modelling, as carried out in OECD Member countries and international organisations, are listed in Part III. The aim is to identify common interests, to establish current coverage of selected issues, and to avoid any duplication of efforts between international agencies. (author). refs., figs., tabs

  19. Analyzing Data Citations to Assess the Scientific and Societal Value of Scientific Data

    Science.gov (United States)

    Chen, R. S.; Downs, R. R.

    2012-12-01

    Stakeholders in the creation, distribution, support, funding, and use of scientific data can benefit by understanding the value that the data have for society and science. For decades, the scientific community has been using citations of articles in the published scientific literature as one of the primary measures used for evaluating the performance of scientists, departments, institutions, and scientific disciplines. Similarly, citations in the published literature of scientific data may be useful for measuring and assessing the value of the scientific data and the performance of the individuals, projects, programs, and organizations that have contributed to the data and their use. The results of citation analysis and other assessments of the value of data also can contribute to planning for future data collection, development, distribution, and preservation efforts. The planned release of new data citation indexes and the more widespread adoption of unique data identifiers and automated attribution mechanisms have the potential to improve significantly the capabilities for analyzing citations of scientific data. In addition, rapid developments in the systems and capabilities for disseminating data, along with education and workforce development on the importance of data attribution and on techniques for data citation, can improve practices for citing scientific data. Such practices need to lead not only to better aggregate statistics about data citation, but also to improved characterization and understanding of the impact of data use in terms of the benefits for science and society. Analyses of citations in the scientific literature were conducted for data that were distributed by an interdisciplinary scientific data center during a five-year period (1997 - 2011), to identify the scientific fields represented by the journals and books in which the data were cited. Secondary citation analysis also was conducted for a sample of scientific publications that used

  20. Gut microbiota, microinflammation, metabolic profile, and zonulin concentration in obese and normal weight subjects.

    Science.gov (United States)

    Zak-Gołąb, Agnieszka; Kocełak, Piotr; Aptekorz, Małgorzata; Zientara, Maria; Juszczyk, Lukasz; Martirosian, Gayane; Chudek, Jerzy; Olszanecka-Glinianowicz, Magdalena

    2013-01-01

    The association between gut microbiota and circulating zonulin level, a marker of intestinal permeability, has not been studied yet. The aim of the study is the assessment of plasma zonulin, haptoglobin and proinflammatory cytokines (TNF- α and IL-6) levels in relation to composition of gut microbiota in obese and normal weight subjects. Circulating inflammation markers, such as TNF- α , sTNFR1, sTNFR2, IL-6, zonulin, and haptoglobin levels were measured and semiquantitative analysis of gut microbiota composition was carried out in 50 obese and 30 normal weight subjects without concomitant diseases. Higher circulating zonulin, TNF- α , sTNFR1, sTNFR2, and IL-6 levels were found in the obese subjects. Plasma zonulin level correlated positively with age (r = 0.43, P zonulin (r = 0.26, P zonulin level was proportional to daily energy intake (r = 0.27, P zonulin level, a potential marker of interstitial permeability.

  1. West Nile Virus workshop: scientific considerations for tissue donors.

    Science.gov (United States)

    Brubaker, Scott A; Robert Rigney, P

    2012-08-01

    This report contains selected excerpts, presented as a summary, from a public workshop sponsored by the American Association of Tissue Banks (AATB) held to discuss West Nile Virus (WNV) and scientific considerations for tissue donors. The daylong workshop was held 9 July 2010 at the Ritz-Carlton Hotel at Tyson's Corner in McLean, Virginia, United States (U.S.). The workshop was designed to determine and discuss scientific information that is known, and what is not known, regarding WNV infection and transmission. The goal is to determine how to fill gaps in knowledge of WNV and tissue donation and transplantation by pursuing relevant scientific studies. This information should ultimately support decisions leading to appropriate tissue donor screening and testing considerations. Discussion topics were related to identifying these gaps and determining possible solutions. Workshop participants included subject-matter experts from the U.S. Food and Drug Administration, the Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Health Canada, the Public Health Agency of Canada, AATB-accredited tissue banks including reproductive tissue banks, accredited eye banks of the Eye Bank Association of America, testing laboratories, and infectious disease and organ transplantation professionals. After all presentations concluded, a panel addressed this question: "What are the scientific considerations for tissue donors and what research could be performed to address those considerations?" The slide presentations from the workshop are available at: http://www.aatb.org/2010-West-Nile-Virus-Workshop-Presentations.

  2. A STUDY OF LIPID PROFILE IN PREDIABETES

    Directory of Open Access Journals (Sweden)

    Manoj

    2016-06-01

    Full Text Available BACKGROUND Lipid abnormalities are common in diabetes mellitus and play an important role in acceleration of atherosclerosis leading to increased cardiovascular diseases. Due to increasing burden of diabetes, it is becoming important to identify dyslipidaemia in high-risk state for diabetes especially prediabetes so that early intervention can reduce cardiovascular risk. AIM To study lipid profile in prediabetes individuals. METHODS This study was a cross-sectional case control study which included 107 prediabetes and 101 healthy controls. Lipid profile of prediabetes and controls were measured and statistically analysed. RESULT Total cholesterol, LDL, triglycerides, VLDL, TG/HDL ratio, and LDL/HDL ratio were significantly high whereas HDL was significantly low in prediabetes subjects as compared to controls. CONCLUSION This study showed significant lipid abnormalities in prediabetes subjects. Because of these they are at high risk of developing atherosclerotic cardiovascular diseases. Therefore, proper screening and appropriate therapy of these conditions becomes important.

  3. The Effect of Social Networks on the Scientific Research Relations, Prospectiveness, Creativity and satisfaction of Scientific Position

    Directory of Open Access Journals (Sweden)

    Alireza Ebrahimpour

    2016-07-01

    Full Text Available Considering the high cultured efficiency of the social networks effective in purposeful directing the life of the users’ lifestyle by emergence and significant development of the social networks. Major changes have taken place in informatics process. The social networks can play role in the production and development of the science and the science as a managed educational program be used in the educational centers. This research investigates the effects of the social networks on the educational relationship among the students and universities. This cross sectional study was performed on 1000 students at 7 medical universities of Iran in 2015. The data collection tool was questionnaire comprised three sections with approved validity. The durability of the α-cronbach coefficient for second part of the questionnaire was 80% and of the third section on the questions with the Likert Criteria was 75%. The obtained data were analyzed by descriptive statistic method of ANOVA, Tukey and X2 using SPSS-19. In this study 940 subjects were under study, of them 85% had the daily use of social networks. Telegram had the highest usage among the users, 52% preferred the image in exchange of view. We found that 85% believed that social networks have effective role on the social relationships. Also 69% of the study subjects believe that the effects of the networks in learning insignificant materials are high. Referring to the obtained data of the present study, it is proposed that the universities use the social networks officially and managed. Establish groups with definite context and help in improvement of the scientific relation level, to be effective in the prospectiveness, creation and consent of the individuals from their scientific situation, in direct procedure.

  4. MISCONCEPTIONS AND NON-SCIENTIFIC CONCEPTS ON FREE RADICALS

    Directory of Open Access Journals (Sweden)

    Rosiris Sindeaux de Alencar Pires de Oliveira

    2016-11-01

    Full Text Available INTRODUCTION: Misconceptions or alternative conceptions are defined as conceptions that are somewhat different from the scientifically accepted ones and are known to be highly resistant to changes. Free radicals are a widely publicized subject in the media due to their putative importance in human aging and health. Free radicals are a subject susceptible to misconceptions widely spread by the media supporting prejudicial advertising inducing antioxidant consumption. OBJECTIVES: Identify and categorized different free radicals misconceptions published in printed media. MATERIALS AND METHODS: Revista Veja (Digital Archive, the weekly magazine with the largest circulation in Brazil, was selected for this investigation. Period analyzed: from 01/01/2000 to 31/07/2014 with search terms Free radicals and antioxidants. Passages selected were classified as: Right Concept (RC, Wrong Concept (WC, Misconception (MC, Inadequate generalization (IG, Inductive [to misconceptions] Concept (IC, Inductive [to misconceptions] Information (II, and Not fit the inclusion criteria (NFIC. Each one of these categories were further subdivided. DISCUSSION AND RESULTS: 79 magazine articles, advertisements and information materials were found which led to 293 text passages. 56.3% were MC, 21.4% II, 8.8% IC, 5.4% IG, 3.4% RC, 2.7% WR, 2.0% NFIC. The most frequently subcategory in each category was: MC: x [something] combats free radicals (22.6%; II: x [substance] is antioxidant (54.0%; IC: x [something] increases free radicals production (34.6%; IG: antioxidant x [substance] combats cancer (56.3%; RC: too much vitamins and minerals is harmful to health (30.0%; WR: free radicals are formed during oxygen conversion to energy process (25.0%. CONCLUSION: Magazine analysis reveal non-scientific concepts (MC, II, IC and IG to be highly frequent, notably misconceptions. Moreover, non-scientific concepts together reach 91.8% of all concepts while right concepts respond for only 2

  5. Roentgenographic studies on the soft tissue profile

    International Nuclear Information System (INIS)

    Park, Tae Won; Ahn, Hyung Kyu

    1971-01-01

    Modern orthodontics implies not only occlusal excellence, but also the positioning of teeth to produce optimal facial harmony for the individual patients. Several methods have been used in the study of facial height, width and depth were made from living subjects. These methods, however, complicate to control the subjects, therefore many investigators have used profile cephalometric technics. Practically, cephalometric technics were used in orthodontic treatment, maxillo-facial surgery and anthropometric studies. Author was studied to investigate the normal standards of soft tissue profile in Korean adolescences. The subjects consisted of 53 males and 54 females from 17 to 22 years of age and with normal occlusion and acceptable profile. Aluminum filter was designed to obtain both hard and soft tissue structures on a single film. Eight profile landmarks were plotted and drawn on the tracings of all cephalograms and eighteen depth, height an d angles were measured from each landmarks of the cephalograms. The following conclusions were obtained from this studies; 1. Total facial convexity was 170.75 in males and females samples and lower facial and labiomandibular convexity were each of 141.44, 171.05. 2. Maxillary and mandibular sulcus angulations were 137.61, 129.52 and upper and lower lip inclinations were each of 12 3.26 and 49.56 in male and females. 3. Soft tissue depth of several points were as follows; Subnasale 18.74 mm in males and 16.65 mm in females Pogonion 13.40 mm in males and 13.07 mm in females upper lip 14.06 mm in males and 11.91 mm in females lower lip 15.46 mm, 13.63 in males and females 4. The protrusion of nose were 16.28 mm in males and 15.56 mm in females 5. The vertical length of upper and lower lips were 25.67 mm, 52.96 mm and the lip posture was indicated 93.43 per cent (closed state) in centric occlusions.

  6. INTEGRATION OF UKRAINIAN INDUSTRY SCIENTIFIC PERIODACLS INTO WORLD SCIENTIFIC INFORMATION SPACE: PROBLEMS AND SOLUTIONS

    Directory of Open Access Journals (Sweden)

    T. O. Kolesnykova

    2013-11-01

    Full Text Available Purpose. Problem of representation lack of scientists’ publications, including transport scientists, in the international scientometric databases is the urgent one for Ukrainian science. To solve the problem one should study the structure and quality of the information flow of scientific periodicals of railway universities in Ukraine and to determine the integration algorithm of scientific publications of Ukrainian scientists into the world scientific information space. Methodology. Applying the methods of scientific analysis, synthesis, analogy, comparison and prediction the author has investigated the problem of scientific knowledge distribution using formal communications. The readiness of Ukrainian railway periodicals to registration procedure in the international scientometric systems was analyzed. The level of representation of articles and authors of Ukrainian railway universities in scientometric database Scopus was studied. Findings. Monitoring of the portals of railway industry universities of Ukraine and the sites of their scientific periodicals and analysis of obtained data prove insufficient readiness of most scientific publications for submission to scientometric database. The ways providing sufficient "visibility" of industry periodicals of Ukrainian universities in the global scientific information space were proposed. Originality. The structure and quality of documentary flow of scientific periodicals in railway transport universities of Ukraine and its reflection in scientometric DB Scopus were first investigated. The basic directions of university activities to integrate the results of transport scientists research into the global scientific digital environment were outlined. It was determined the leading role of university libraries in the integration processes of scientific documentary resources of universities into the global scientific and information communicative space. Practical value. Implementation of the proposed

  7. Digitized video subject positioning and surveillance system for PET

    International Nuclear Information System (INIS)

    Picard, Y.; Thompson, C.J.

    1995-01-01

    Head motion is a significant contribution to the degradation of image quality of Positron Emission Tomography (PET) studies. Images from different studies must also be realigned digitally to be correlated when the subject position has changed. These constraints could be eliminated if the subject's head position could be monitored accurately. The authors have developed a video camera-based surveillance system to monitor the head position and motion of subjects undergoing PET studies. The system consists of two CCD (charge-coupled device) cameras placed orthogonally such that both face and profile views of the subject's head are displayed side by side on an RGB video monitor. Digitized images overlay the live images in contrasting colors on the monitor. Such a system can be used to (1) position the subject in the field of view (FOV) by displaying the position of the scanner's slices on the monitor along with the current subject position, (2) monitor head motion and alert the operator of any motion during the study and (3) reposition the subject accurately for subsequent studies by displaying the previous position along with the current position in a contrasting color

  8. A Complexity Approach to Evaluating National Scientific Systems through International Scientific Collaborations

    Science.gov (United States)

    Zelnio, Ryan J.

    2013-01-01

    This dissertation seeks to contribute to a fuller understanding of how international scientific collaboration has affected national scientific systems. It does this by developing three methodological approaches grounded in social complexity theory and applying them to the evaluation of national scientific systems. The first methodology identifies…

  9. [Financing of the scientific publication and protection of the scientific knowledge].

    Science.gov (United States)

    Oliveira Filho, Renato Santos de; Hochman, Bernardo; Nahas, Fabio Xerfan; Ferreira, Lydia Masako

    2005-01-01

    The main purpose of a study is its publication on a scientific journal. Research financing agencies are important institutions so that studies can be developed and published. The most important research financing agencies that are discussed in this article are: "Coordenação de Aperfeiçoamento de Pessoal de Nível Superior" (CAPES), "Conselho Nacional de Desenvolvimento Científico e Tecnológico" (CNPq) and "Fundação de Amparo à Pesquisa do Estado de São Paulo" (FAPESP). CAPES' activities can be grouped in four different strategy lines: a) it evaluates the stricto sensu, at the post-graduation level; b) it provides access and development of scientific research; c) it provides investment on the development of high qualified human resources in Brazil and abroad, and d) it promotes international scientific cooperation. Although CAPES does not support directly scientific publications, almost all actions of this agency contribute to the development of scientific research and publication. CNPq has two main purposes: financing researches and development of human resources. It provides the researchers with financial aid to scientific publication. The grants for editing were specifically created for supporting the national scientific and technical publications edited by Brazilians institutions or societies. CNPq can also support Congresses, Symposiums and similar short-term courses. The Plataforma Lattes is also a branch of CNPq on which the Curriculum Lattes is available. This site has the curriculum vitae of the scientific community and is of great value for researchers. FAPESP also finances journal publications, articles and books that bring up original results of studies made by researchers from the state of São Paulo. It finances, partially, the travel expenses of innovative papers authors in meetings within the country or abroad. Brazilian authors are increasing the number of international publications. Universities, research institutes, financing agencies and

  10. Investigation of the Effect of Training on the Development of High School Teachers' Attitudes towards Scientific Research and Project Competitions

    Science.gov (United States)

    Akçöltekin, Alptürk

    2016-01-01

    The main purpose of this study is to develop positive attitudes in high school teachers towards scientific research and project competitions by training them in scientific research and project preparation subjects. The study group consists of 90 high school teachers. As a result of the study, a significant difference was found in favor of…

  11. On the Possibility of a Scientific Theory of Scientific Method.

    Science.gov (United States)

    Nola, Robert

    1999-01-01

    Discusses the philosophical strengths and weaknesses of Laudan's normative naturalism, which understands the principles of scientific method to be akin to scientific hypotheses, and therefore open to test like any principle of science. Contains 19 references. (Author/WRM)

  12. Mixing Languages during Learning? Testing the One Subject-One Language Rule.

    Directory of Open Access Journals (Sweden)

    Eneko Antón

    Full Text Available In bilingual communities, mixing languages is avoided in formal schooling: even if two languages are used on a daily basis for teaching, only one language is used to teach each given academic subject. This tenet known as the one subject-one language rule avoids mixing languages in formal schooling because it may hinder learning. The aim of this study was to test the scientific ground of this assumption by investigating the consequences of acquiring new concepts using a method in which two languages are mixed as compared to a purely monolingual method. Native balanced bilingual speakers of Basque and Spanish-adults (Experiment 1 and children (Experiment 2-learnt new concepts by associating two different features to novel objects. Half of the participants completed the learning process in a multilingual context (one feature was described in Basque and the other one in Spanish; while the other half completed the learning phase in a purely monolingual context (both features were described in Spanish. Different measures of learning were taken, as well as direct and indirect indicators of concept consolidation. We found no evidence in favor of the non-mixing method when comparing the results of two groups in either experiment, and thus failed to give scientific support for the educational premise of the one subject-one language rule.

  13. Statistical Analysis of the Association Between Subject Headings and Their Corresponding Class Notations in Science and Technology Monographs.

    Science.gov (United States)

    Khosh-khui, Abolghasem

    This study investigates the degree of relationship between scientific and technical subject headings and their corresponding class notations in the Dewey Decimal (DDC) and Library of Congress Classification (LCC) systems. The degree of association between a subject heading and its corresponding class of notation or notations is measured by…

  14. A Multi-Level Analysis of World Scientific Output in Pharmacology

    OpenAIRE

    Olmeda-Gómez, Carlos; Ovalle-Perandones, María Antonia; Perianes-Rodríguez, Antonio

    2012-01-01

    The purpose of this chapter is to analyse international research in “pharmacology, toxicology and pharmaceutics” (hereafter pharmacology) on the basis of the scientific papers listed in the Scopus multidisciplinary database. This primary objective is reached by answering the following questions (in the section on results). What weight does the subject area “pharmacology, toxicology and pharmaceutics” carry in world-wide science? What is the percentage contribution made by the various regions ...

  15. Expectations for a scientific collaboratory

    DEFF Research Database (Denmark)

    Sonnenwald, Diane H.

    2003-01-01

    In the past decade, a number of scientific collaboratories have emerged, yet adoption of scientific collaboratories remains limited. Meeting expectations is one factor that influences adoption of innovations, including scientific collaboratories. This paper investigates expectations scientists have...... with respect to scientific collaboratories. Interviews were conducted with 17 scientists who work in a variety of settings and have a range of experience conducting and managing scientific research. Results indicate that scientists expect a collaboratory to: support their strategic plans; facilitate management...... of the scientific process; have a positive or neutral impact on scientific outcomes; provide advantages and disadvantages for scientific task execution; and provide personal conveniences when collaborating across distances. These results both confirm existing knowledge and raise new issues for the design...

  16. Experience-Oriented Knowledge Organisation for the Transference of Scientific Knowledge from Universities to SMEs

    DEFF Research Database (Denmark)

    Lykke, Marianne; Løkkegaard, Sarai; Jantzen, Christian

    2017-01-01

    referred to as generic pathways (e.g. scientific publishing) and relational pathways (e.g. faculty consulting). The purpose of this research is to extend our knowledge about the design of generic pathways. The analysis is concentrated on the knowledge organisation system for a research management system......Transferring scientific knowledge between universities and industry is known to be problematic, specifically for small and medium-sized enterprises (SMEs) that have limited resources and absorption capacity. A variety of channels is used for knowledge transfer. These include what is commonly...... - how to meet the characteristics of SMEs in the design of subject categories in the navigation system and in the presentation of the scientific knowledge by controlled and uncontrolled keywords and descriptive annotations. The design suggestions are based on findings from a qualitative situation...

  17. Oceanographic profile temperature and salinity measurements collected using bottle from the Zarnitsa in the Barents Sea (NODC Accession 0002235)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature and salinity profile data from the SCIENTIFIC ICHTIOLOGICAL INSTITUTE OF LENINGRAD (RUSSIA), digitized from "Bulletin of the Institute of Ichthyology,...

  18. Association of cardiometabolic risk profile with prehypertension accompany hyperhomocysteinaemia.

    Science.gov (United States)

    Chen, Huili; Sun, Yuemin; Wang, Xuechun; Si, Quan; Yao, Wei; Wan, Zheng

    2015-01-01

    Study suggested that elevated homocysteine showed a multiplicative effect on cardiovascular diseases in hypertensive subjects. It was reported that elevated homocysteine level was independently associated with increased arterial stiffness in prehypertensives. It remains unclear whether prehypertensives combined with elevated homocysteine have adverse cardiovascular risk factors. We aimed to compare cardiometabolic risk profile between prehypertensives with hyperhomocysteinaemia and those without either condition. Plasma total homocysteine and risk profile were determined among 874 Chinese non-hypertension individuals in Tianjin. They were subdivided into four groups: prehypertension with hyperhomocysteinaemia (≥10 μmol/L), prehypertension with normal homocysteine (risk profile. Strict lipid management and weigh control may be needed in prehypertensives with elevated homocysteine.

  19. Enhancing Scientific Inquiry Literacy of Prospective Biology Teachers through Inquiry Lab Project in Microbiology

    Science.gov (United States)

    Kusnadi, K.; Rustaman, N. Y.; Redjeki, S.; Aryantha, I. N. P.

    2017-09-01

    The implementation of the inquiry laboratory based project to enhance scientific inquiry literacy of prospective biology teachers in Microbiology course has been done. The inquiry lab based project was designed by three stages were debriefing of basic microbiology lab skills, guided inquiry and free inquiry respectively. The Study was quasi experimental with control group pretest-posttest design. The subjects were prospective biology teachers consists of 80 students. The scientific inquiry literacy instrument refers to ScInqLiT by Wenning. The results showed that there was significant difference of scientific inquiry literacy posttest scores between experiment and control (α 0,05) and was obtained N-gain score was 0.49 (medium) to experiment and 0.24 (low) to control. Based on formative assessment showed that development of student’s scientific attitude, research and microbiology lab skills during conducting project were increased. Student’s research skills especially in identification of variables, constructing a hypothesis, communicating and concluding were increased. During implementation of inquiry project also showed that they carried out mind and hands-on and so collaborative group investigation lab activities. Our findings may aid in reforming higher-education, particularly in microbiology laboratory activities to better promote scientific inquiry literacy, scientific attitude, research and laboratory skills.

  20. On the Dichotomy of Qualitative and Quantitative Researches in Contemporary Scientific Methodology

    Directory of Open Access Journals (Sweden)

    U V Suvakovic

    2011-12-01

    Full Text Available Argumentation in favor of overcoming the long-ago-established dichotomy of qualitative and quantitative scientific research is presented in the article. Proceeding from the view of materialistic dialecticians that every scientific research must deal with a subject, the author assumes that it is impossible to conduct a quantitative research without first establishing the quality to be studied. This also concerns measuring, which is referred only to quantitative procedures in literature. By way of illustration, the author designs two instruments for measuring the successfulness of political parties - the scale and the quotient of party successfulness. On the other hand, even the qualitative analysis usually involves certain quantifications. The author concludes that to achieve methodological correctness the existing dichotomy of qualitative and quantitative research should be considered as overcome and a typology of scientific research including predominantly qualitative and predominantly quantitative studies, depending on the methodological components prevailing in them, should be used.

  1. Discursive geographies in science: space, identity, and scientific discourse among indigenous women in higher education

    Science.gov (United States)

    Brandt, Carol B.

    2008-09-01

    Despite completing undergraduate degrees in the life sciences, few Indigenous women choose to pursue careers in scientific research. To help us understand how American Indian students engage with science, this ethnographic research describes (1) how four Navajo women identified with science, and (2) the narratives they offered when we discussed their experiences with scientific discourse. Using intensive case studies to describe the experiences of these women, my research focused on their final year of undergraduate study in the life sciences at a university in southwestern US. I point to the processes by which the participants align themselves with ideas, practices, groups, or people in science. As each participant recounted her experiences with scientific discourse, they recreated for me a discursive geography of their lives on the reservation, at home, at community colleges (in some cases), and on the university campus. In the construction and analysis of the narratives for this research, mapping this geography was critical to understanding each participant's discursive relationship with science. In these discursive spaces, I observed productive "locations of possibility" in which students and their instructors: valued connected knowing; acknowledged each other's history, culture, and knowledge; began to speak to each other subject-to-subject; and challenged normative views of schooling. I argue that this space, as a location of possibility, has the power to transform the crushing impersonalized schooling that often characterizes "rigorous" scientific programs in a research institution.

  2. Profile formation of academic self-concept in elementary school students in grades 1 to 4.

    Directory of Open Access Journals (Sweden)

    Isabelle Schmidt

    Full Text Available Academic self-concept (ASC is comprised of individual perceptions of one's own academic ability. In a cross-sectional quasi-representative sample of 3,779 German elementary school children in grades 1 to 4, we investigated (a the structure of ASC, (b ASC profile formation, an aspect of differentiation that is reflected in lower correlations between domain-specific ASCs with increasing grade level, (c the impact of (internal dimensional comparisons of one's own ability in different school subjects for profile formation of ASC, and (d the role played by differences in school grades between subjects for these dimensional comparisons. The nested Marsh/Shavelson model, with general ASC at the apex and math, writing, and reading ASC as specific factors nested under general ASC fitted the data at all grade levels. A first-order factor model with math, writing, reading, and general ASCs as correlated factors provided a good fit, too. ASC profile formation became apparent during the first two to three years of school. Dimensional comparisons across subjects contributed to ASC profile formation. School grades enhanced these comparisons, especially when achievement profiles were uneven. In part, findings depended on the assumed structural model of ASCs. Implications for further research are discussed with special regard to factors influencing and moderating dimensional comparisons.

  3. Love as a subjective corrlate of interpersonal relationships: attempts of defining of the concepts and methods of measurment

    Directory of Open Access Journals (Sweden)

    O. P. Zolotnyik

    2015-04-01

    Full Text Available This article is devoted to overview the scientific study of the phenomenon of love. Attempts of scientific knowledge presented by developed by sociologists and psychologists love theories, which defined, classified and measure this phenomenon. The paper proposed to review the most popular theory of love studying: the triangular theory of love for Robert J. Sternberg, classification styles love for John Alan Lee and transformational concept of A.Giddens. The importance of studying this subject is explained by the subjective definition by respondents of the role of love as correlates of interpersonal relationships. Love is considered as a factor that acts as a marriage motive and components, which ensures its durability. The complexity of the scientific understanding of love is the absence of clear empirical referents for fixation. The examined theory reaffirms their scientific hypotheses through the use of specific methods of measurement. It is offered for review: Scale of love and sympathy by Z.Rubin, Love Attitude Scale by Hendrick C. and Hendrick S. and scale of romantic relationships by Munro­Adams. These methodologies are widely used in modern scientific research, been undergo with modifications and adaptation depending on the cultural characteristics of the respondents. The phenomenon of love needs more scientific study with the aim of further categorization, require range of techniques selection and should be included  as a component in the sociological survey of interpersonal relationships.

  4. Dissociative features in posttraumatic stress disorder: A latent profile analysis.

    Science.gov (United States)

    Műllerová, Jana; Hansen, Maj; Contractor, Ateka A; Elhai, Jon D; Armour, Cherie

    2016-09-01

    The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) characterizes the dissociative subtype of posttraumatic stress disorder (PTSD) in terms of the individual meeting the criteria for PTSD and additionally reporting symptoms of depersonalization and/or derealization. The current study aimed to examine whether a dissociative PTSD profile may include alternative features of dissociation and whether it could be differentiated from a nondissociative PTSD profile on certain psychopathologies and demographics. Data from 309 trauma-exposed participants, collected through Amazon Mechanical Turk, were subjected to latent profile analysis. Regression analyses were used to examine the predictors of latent classes. Three discrete profiles named Baseline, PTSD, and Dissociative profile were uncovered. All examined features of dissociation were significantly elevated in the Dissociative profile. Anxiety, male sex, being employed, and having a minority racial background significantly predicted the Dissociative profile relative to the PTSD profile. The study points to the importance of alternative symptoms of dissociation in the dissociative PTSD subtype beyond the symptoms of depersonalization and derealization. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  5. Association between muscle mass and adipo-metabolic profile: a cross-sectional study in older subjects

    Directory of Open Access Journals (Sweden)

    Perna S

    2015-02-01

    Full Text Available Simone Perna,1,* Davide Guido,2,* Mario Grassi,2 Mariangela Rondanelli1 1Department of Public Health, Experimental and Forensic Medicine, School of Medicine, Endocrinology and Nutrition Unit, University of Pavia, Azienda di Servizi alla Persona di Pavia, Pavia, Italy; 2Medical and Genomic Statistics Unit, Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy *These authors contributed equally to this work Background: Sarcopenia, the decrease in muscle mass and function, may lead to various negative health outcomes in elderly. The association among sarcopenia with adiposity and metabolic markers has rarely been studied in the elderly population, with controversial results. The aim of this study is to evaluate this relationship in older subjects.Methods: A cross-sectional study was conducted in 290 elderly patients, focusing on the possible association between muscle mass loss, assessed by relative skeletal muscle mass (RSMM, and an adipo-metabolic profile (AMP defined by adiposity and metabolic biochemical markers. Measurements of body composition were assessed by dual energy X-ray absorptiometry. Biochemical parameters, such as albumin, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, total cholesterol, triglycerides, C-reactive protein, and homocysteine and its related markers (folate and vitamin B12 were measured. Using canonical correlation analysis and structural equation modeling, an individual score of AMP was created and correlated with RSMM.Results: The AMP–RSMM correlation was equal to +0.642 (95% confidence interval, +0.512 to +0.773; P<0.001. Hence, a negative association between sarcopenia severity and adiposity/metabolic biochemical markers was highlighted.Conclusion: This study contained a novel way to examine the relationship between the variables of interest based on a composite index of adiposity and metabolic conditions. Results shed light on the orientation and magnitude of

  6. The paradox of scientific expertise

    DEFF Research Database (Denmark)

    Alrøe, Hugo Fjelsted; Noe, Egon

    2011-01-01

    Modern societies depend on a growing production of scientific knowledge, which is based on the functional differentiation of science into still more specialised scientific disciplines and subdisciplines. This is the basis for the paradox of scientific expertise: The growth of science leads to a f...... cross-disciplinary research and in the collective use of different kinds of scientific expertise, and thereby make society better able to solve complex, real-world problems.......Modern societies depend on a growing production of scientific knowledge, which is based on the functional differentiation of science into still more specialised scientific disciplines and subdisciplines. This is the basis for the paradox of scientific expertise: The growth of science leads...... to a fragmentation of scientific expertise. To resolve this paradox, the present paper investigates three hypotheses: 1) All scientific knowledge is perspectival. 2) The perspectival structure of science leads to specific forms of knowledge asymmetries. 3) Such perspectival knowledge asymmetries must be handled...

  7. Peer Review in Scientific Publications: Benefits, Critiques, & A Survival Guide

    Science.gov (United States)

    Kelly, Jacalyn; Sadeghieh, Tara

    2014-01-01

    Peer review has been defined as a process of subjecting an author’s scholarly work, research or ideas to the scrutiny of others who are experts in the same field. It functions to encourage authors to meet the accepted high standards of their discipline and to control the dissemination of research data to ensure that unwarranted claims, unacceptable interpretations or personal views are not published without prior expert review. Despite its wide-spread use by most journals, the peer review process has also been widely criticised due to the slowness of the process to publish new findings and due to perceived bias by the editors and/or reviewers. Within the scientific community, peer review has become an essential component of the academic writing process. It helps ensure that papers published in scientific journals answer meaningful research questions and draw accurate conclusions based on professionally executed experimentation. Submission of low quality manuscripts has become increasingly prevalent, and peer review acts as a filter to prevent this work from reaching the scientific community. The major advantage of a peer review process is that peer-reviewed articles provide a trusted form of scientific communication. Since scientific knowledge is cumulative and builds on itself, this trust is particularly important. Despite the positive impacts of peer review, critics argue that the peer review process stifles innovation in experimentation, and acts as a poor screen against plagiarism. Despite its downfalls, there has not yet been a foolproof system developed to take the place of peer review, however, researchers have been looking into electronic means of improving the peer review process. Unfortunately, the recent explosion in online only/electronic journals has led to mass publication of a large number of scientific articles with little or no peer review. This poses significant risk to advances in scientific knowledge and its future potential. The current

  8. Cardiovascular Disease Risk Factors Profile in Individuals With Diabetes Compared With Non-Diabetic Subjects in North-East of Iran.

    Science.gov (United States)

    Niroumand, Shabnam; Dadgarmoghaddam, Maliheh; Eghbali, Babak; Abrishami, Maryam; Gholoobi, Arash; Bahrami Taghanaki, Hamid Reza; Khajedaluee, Mohammad

    2016-08-01

    Diabetes mellitus is assumed to be a strong risk factor for cardiovascular diseases (CVD) and is frequently associated with other CVD risk factors. The aims of this study were to assess the prevalence of different patterns of dyslipidemia in individuals with diabetes compared with non-diabetic subjects and evaluate other accompanied CVD risk factors between the two groups. This was an analytical cross-sectional study on 230 participants, aged 28 - 66 years old, who were referred to different urban health centers of Khorasan Razavi province (north-east of Iran). Data from the participants were collected during their first visit by primary care physicians. Statistical package for social science (version 11.5) was used to analyze the data. The chi-square or Fisher's exact, student's t or the Mann-Whitney U and correlation tests were used in the analysis. The age and gender of the participants were not different between the two groups (P = 0.1 and P = 0.4, respectively). The most common patterns of dyslipidemia in both groups were isolated dyslipidemia followed by combined dyslipidemia. Prevalence of dyslipidemia as a whole (one, two or three lipid profile abnormalities) in patients with diabetes and non-diabetic participants was 89.3% and 82.6%, respectively and the difference between the two groups was not statistically significant (P = 0.1). Subjects with diabetes had higher systolic blood pressure (P index (P = 0.09) compared to non-diabetics. Moreover, they were more likely to have higher levels of total cholesterol (P = 0.01), triglycerides (P = 0.001) and low density lipoprotein cholesterol (P = 0.009) and lower levels of high density lipoprotein cholesterol (P = 0.2). Cardiovascular diseases risk factors are more common in patients with diabetes; however, non-diabetic individuals also had a high prevalence of risk factors in our region, predisposing them to diabetes. Therefore, further attention by the medical community is necessary to choose effective

  9. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically-Synonymous?

    Science.gov (United States)

    Meissner, Henry O.; Mscisz, Alina; Kedzia, Bogdan; Pisulewski, Pawel; Piatkowska, Ewa

    2015-01-01

    Using Liquid Chromatography-Mass Spectrometry (LCMS) , profiles of the two isotypes labelled under the same common name Maca deposited in the Medicinal Plant Herbarium, in Australia and Poland, but identified under two different scientific names Lepidium meyenii Walpers (L. meyenii) and Lepidium peruvianum Chacon (L. peruvianum) are presented. The two isotypes correspond to two holotypes of Peruvian medicinal herb known under the same common name “Maca”, as originally deposited in the Herbarium of San Marcos University in Lima, Peru dated back to 1843 and 1990 respectively. The results demonstrate distinct differences in taxonomy, visual appearance, phytochemical profiles and DNA sequences of the two researched Maca isotypes, suggesting that the two Maca specimens are dissimilar and formal use of the term “synonymous” to L. meyenii and L. peruvianum may be misleading. On the basis of presented results the scientific name L. meyenii, used since 1843 up-today for cultivated Peruvian Maca by numerous reference sources worldwide, including Regulatory Bodies in the USA, EU, Australia and most lately in China, appears to be used in error and should be formally revised. It is concluded, that the isotype of cultivated Peruvian Maca labelled under its scientific name Lepidium peruvianum Chacon, provides all the characteristics peculiar to this historically-documented herb grown in Andean highlands, which may be linked to its traditional use and accepted functionality, confirmed in recent clinical study to be relevant to its present day use for expected dietary, therapeutic and health benefits.

  10. [Journal AMHA - Acta medico-historica Adriatica: 14 years of patient work on the scientific valorisation of the history of medicine].

    Science.gov (United States)

    Eterović, Igor

    2017-12-01

    In this paper the first 14 years of publication of scientific journal AMHA - Acta medico‑historica Adriatica (2002-2016) are presented and shortly analysed. This journal has undoubtedly become and remained the central activity of the Croatian Scientific Society for the History of Health Culture, which has rapidly become a globally esteemed journal of history of medicine. The beginning and the context of publishing the journal with the reference to scientific meeting "Rijeka and Its Citizens in Medical History" is presented, as well as the journal's profiling into distinguished international journal and its fast development in later years. The analysis shows the growth of journal's visibility through indexation in different international journal databases, the number and ratio of scientific articles and the variety of published material. Finally, a review of the potential future directions of development and the significance of this journal within the national, regional and international context is given.

  11. PERSONALITY AS SUBJECT OF THE RELATION TO THE STRESS

    Directory of Open Access Journals (Sweden)

    Milena Aleksandrovna Klenova

    2015-08-01

    Full Text Available In this scientific article results of the empirical research devoted to studying of the personality as the subject of the relation to a stress are presented. The understanding of a phenomenon of a stress not only taking into account social and psychological features of the personality, but also with inclusion of such category as representations of a stress and the relation towards him for the first time is considered by authors. In empirical research it is established that there are five types of the personality, as subjects of the relation to a stress according to their social and psychological features and ideas of a stress. «Destructive persons» – differ in the reduced level of social and psychological adaptation, they are motivated on failure, and the stress is perceived by them as emotional excitement. «Constructive persons» possess the high level of social and psychological adaptation, are focused on success, for them emotional burning out isn’t characteristic, and their representations and the relation to a stress is based on acceptance of existence of eustressor. «Emotional and intense persons» differ in uneasiness, high level of emotional burning out, and their ideas of a stress are based only on negative characteristics. «Sensitive persons» are characterized by the high level of sensitivity, and their relation to a stress can be defined as «mental anguish». For «rational persons» cognitive approach to a situation of a stress and idea of it as about response of an organism to negative emotions is peculiar. Thus, this scientific article represents results of original research of the personality from a position of its relation to a stress.Purpose: to study social and psychological features of the personality with inclusion of such category as «representations and the relation to a stress».Method or methodology of research it is based on the concept of social representations of S.Moskovichi, and also on the subject

  12. Scientific Productivity of Dentistry in Iranian Journals during 1978-2006

    Directory of Open Access Journals (Sweden)

    Roghie Eskroochi

    2010-12-01

    Full Text Available   This investigation is an attempt to study growth and development of scientific products in dentistry using scientometrics in Iran during 1978-2006.   In this project, 2726 dentistry articles published in Iranian journals during a specific period; including Persian and English articles, were collected. Then subjects of all articles were specified using MESH and NLM classification systems.   In Persian dentistry journals, dentistry journal of Shahid Beheshti University of Medical Science has published 804 articles during a specific period that includes 35/07% of all articles; therefore it falls in the first rank.   Among 2726 articles collected, 2102 Persian articles and 95 English articles were written by a team and 520 Persian articles and 9 English articles by individuals.   Maximum number of articles belonged to Prosthodontics and minimum number of articles were on Oral and Maxillofacial pathology.   Scientific outputs in dentistry in Iran have undergone an ascending growth since 2000 and it reached its highest level with 360 scientific articles in 2006.   This investigation indicates the evolutionary trend and dramatic growth in number of dentistry articles published in Iranian journals.

  13. Scientific Management as part of the curriculum of Pedagogical Sciences.

    Directory of Open Access Journals (Sweden)

    Martha Margarita López Ruiz

    2013-07-01

    Full Text Available The Psychology and Pedagogy carer is developed in pedagogical sciences Cuban universities and the plan of the teaching learning process is organized on disciplines, subjects and activities from the working practice are distributed during the five years of the career which guarantee the fulfilment of the objectives in the professional qualification degree. Scientific educational management is included as part of the curriculum of this specialty in Pedagogical Universities. Scientific educational management has a great importance in the existence of state who is worried for the preparation and training of pedagogical specialists to whom ethics becomes a daily practice in their jobs in a society in which the formation and development of Cuban citizens is carried out by social programs encouraged by the government. The growing of this specialist is supported on the existence of a government that is interested on teaching, innovate and develop human beings by means of putting into practice social and cultural activities. The main goal of this article is to exemplify how to organize the contents of scientific educational management and the way of planning the teaching learning process to better future Cuban teacher trainers and managers.

  14. [Therapeutic potential of Hibiscus sabdariffa: a review of the scientific evidence].

    Science.gov (United States)

    Guardiola, Soledad; Mach, Núria

    2014-05-01

    Infusion of Hibiscus sabdariffa (H. sabdariffa) is a very popular drink in many parts of the world. Its phytochemical composition is associated to antioxidant, hypotensive, and antiatherosclerotic effects. However, the molecular mechanisms involved in these processes are not well known. The aim of this review was to report the scientific evidence supporting that regular use of H. sabdariffa decreases oxidative stress, atherosclerosis, lipid profile, and blood pressure. A search of recent publications was made in the following specialized electronic databases: Elsevier Journal, SciELO, FSTA, Science Direct, Springer Link, and NCBI. Results of research conducted in clinical trials in humans and in animal models and cell cultures were recorded. Keywords used included Hibiscus sabdariffa, oxidative stress, polyphenols, hypertension, atherosclerosis, and lipid profile. Results of the different articles suggested a possible therapeutic effect of H. sabdariffa extracts on oxidative stress, lipid profile, hypertension, and atherosclerosis thanks to its composition rich in phenolic compounds. Anthocyanins significantly decrease LDL oxidation, inhibit adipogenesis by regulating adipogenic signaling pathways and transcription factors, and modulate gene expression of certain microRNAs. No adverse events or side effects were reported. Further more homogeneous, placebo-controlled studies in humans are needed to state that H. sabdariffa has therapeutic efficacy in humans. Copyright © 2013 SEEN. Published by Elsevier Espana. All rights reserved.

  15. Acquisition in different and special subject areas

    CERN Document Server

    Katz, Linda S

    2013-01-01

    Learn how acquisitions librarians successfully serve specialized users! In this book, you'll find profiles, methods, and processes for acquisitions in specialized subject areas, such as local and regional poetry, oceanography, educational information in electronic formats, popular fiction, regional and ethnic materials, and more. Seasoned acquisitions librarians share their experiences in gathering the hard-to-find materials their libraries' highly specialized clients need to access. You'll also examine issues surrounding the acquisition of new reference tools that are vital in today's emergi

  16. Effect of age and sex on the association between lipid profile and obesity among telecomunication workers in Palembang

    Directory of Open Access Journals (Sweden)

    Hardi Darmawan

    2007-12-01

    Full Text Available The study objective is to examine the effects of age and sex on the association between various obesity parameters and lipid profile. The measurements of whole body obesity (body fat, body fat % and BMI, abdominal obesity (waist to hip ratio, waist to thigh ratio and waist circumference and lipid profile (HDL, LDL, VLDL, total cholesterol and triglyceride were performed on 112 telecom workers in Palembang (84 men and 28 women, age 25, 35, 45, and 55 years. All lipid parameters results depend on sex and age of subjects. The association between obesity assessments and HDL or LDL was independent of sex and age of subjects, whereas the association between obesity assessments and total cholesterol, VLDL and triglyceride is dependent on sex and age of subjects. Abdominal obesity has greater effect on VLDL and triglyceride levels than on other lipid parameters. Whole body obesity has equal effects on all lipid parameters. When comparing results of male and female subjects, obesity measurements and lipid profile association is stronger in male subjects of almost all age groups. The exception is a stronger association between abdominal obesity and VLDL or triglyceride levels in 45 years old female subjects. Obesity measurements and VLDL or triglyceride level association is independent of age, whereas obesity and total cholesterol association is stronger in younger subjects. (Med J Indones 2007; 16:251-6Keywords: Lipid profile, fat distribution, obesity, abdominal obesity

  17. Serum profile of cytokines interferon gamma and interleukin-10 in ewes subjected to artificial insemination by cervical retraction.

    Science.gov (United States)

    Alvares, C T G; Cruz, J F; Romano, C C; Brandão, F Z

    2016-04-15

    This study evaluated the influence of artificial insemination (AI) by cervical retraction (CRI) on serum levels of interferon gamma (IFNγ) and interleukin-10 (IL-10) in ewes. Synchronized pluriparous Santa Inês ewes were subjected to natural mating (NM, n = 8) and AI, which was performed for a fixed time (55 ± 1 hour) by CRI (n = 8) or laparoscopy (n = 8). Ewes were classified as pregnant, with return to estrus (RE) or with embryonic loss (EL). Blood samples were collected on Day 0, Day 3, Day 5, Day 12, and Day 17 (Day 0 = AI/NM) for progesterone dosage and cytokines were quantified from Day 0 to Day 12. Progesterone levels were constant, except for a decrease in ewes with RE at Day 17 (P ewes with EL had lower serum levels of IFNγ and IL-10 than pregnant ewes and ewes with RE, regardless of the reproductive method used, with averages of 769.1, 714.9, and 555.7 pg/mL for IFNγ and 713.8, 699.3, and 578.7 pg/mL for IL-10 in pregnant ewes, ewes with RE and EL, respectively (P ewes does not alter the profile of serum cytokines IFNγ and IL-10 and does not induce an inflammatory reaction that can compromise pregnancy. Copyright © 2016 Elsevier Inc. All rights reserved.

  18. Environmentalmarketing: An Analysis of National Scientific Production

    Directory of Open Access Journals (Sweden)

    Weslei Maique Oliveira Lopes

    2016-09-01

    Full Text Available This research aims to identify the trends and directions of environmental marketing in Brazil, from a survey of national scientific production, the last ten years period (2006-2015 in order to identify possible evolutionary changes in the orientation and implementation of marketing. As methodology, the research adopted an exploratory character with a qualitative approach and the literature as collection instrument. In scientific journals of Directors of Brazil (Qualis A1 to B3 were searched all items with the subject matter "marketing". The results showed that the green marketing publications correspond to 6.88% of articles over the last ten years. With existing publications may be noted that many companies make use of green marketing only as another business strategy to gain market share or practice environmental management only when necessary as in the case of regulatory laws. Thus, based on Brazilian studies, it appears that environmental marketing is a source of competitive advantage, but is not yet part of the organizational culture. Therefoen, it presents a research agenda with some propositions in the feeling of contributing to the advancement of environmental marketing practice in companies.

  19. Problems of determination of principle of psychological profile of unknown criminal person in investigational activity

    Directory of Open Access Journals (Sweden)

    Galina Getman

    2017-03-01

    By the author of the article of analysis different determinations of «psychological profile of unknown criminal person» were subjected. They are set positive lines and separate positions that in opinion of author are not expedient and important are subjected to criticism. That is why, the author points in conclusions the argued positions in relation to the necessity of the use of psychological profile of  unknown criminal person during investigation of criminal realizations in activity of investigator.

  20. Scientifically Based Research in Educational Products: Vendors and Consumers on Filling the Certification Gap

    Science.gov (United States)

    Caruthers, Bill J.

    2009-01-01

    The 2002 reauthorization of the Elementary and Secondary Education Act, or No Child Left Behind (NCLB) changed school law in the United States. Public schools can utilize federal funds to purchase only those educational products subject to scientifically based research. No dedicated certification intermediary (CI) exists to determine individual…

  1. Professional organisation profile: a faculty of expedition and wilderness medicine for Australasia.

    Science.gov (United States)

    Leggat, Peter A; Shaw, Marc T M

    2012-05-01

    A profile of the recent genesis of the Sub-Faculty of Expedition Medicine into a Faculty of Expedition and Wilderness Medicine of The Australasian College of Tropical Medicine is presented. Information is given on aims, structure, professional grades of membership, and the various activities of the Faculty, including publications and scientific meetings. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. [Asbestos in pre-industrial times: from natural wonder to subject of scientific investigation].

    Science.gov (United States)

    Carnevale, F

    2012-01-01

    The author proposes a reading of "Concerning incombustible flax or asbestos stone" which was published in 1696 by Giovanni Giustino Ciampini, who was a historian, a man of the church and scientist in Rome. The text, which was originally written in Latin, is an excellent and early description of the need felt by the majority of scientists in Europe at that time for a change in method: that is, to use scientific experiments to explain and control the natural phenomena observed and even perhaps mythologized right from antiquity. In the case of asbestos this was necessary to check the veracity and consistency of a series of recommendations handed down by the earliest authors but also to revive and reinvent the techniques that had largely been lost so as to be able to utilize and develop a substance that it was thought could be of great benefit to society. In the presentation of Ciampini's text an attempt is made to recall and contextualize the earliest knowledge on asbestos and follow its evolution over a long historical period, up to the first half of the nineteenth century. It can thus be seen how asbestos, once considered "a wonder of nature", became a raw material widely used in industrial applications. The most significant steps in this phase of transformation were taken thanks to Italian entrepreneurs and technicians and to the presence of asbestos in the Alpine valleys of Italy.

  3. Blood cell gene expression profiling in subjects with aggressive periodontitis and chronic arthritis

    DEFF Research Database (Denmark)

    Sørensen, Lars K; Poulsen, Anne Havemose; Sønder, Søren U

    2008-01-01

    with untreated localized aggressive periodontitis (LAgP) or generalized aggressive periodontitis (GAgP). Differentially expressed genes were validated in groups of subjects with LAgP, GAgP, juvenile idiopathic arthritis (JIA), or rheumatoid arthritis (RA) and controls. METHODS: Candidate genes were identified...

  4. Open scientific communication urged

    Science.gov (United States)

    Richman, Barbara T.

    In a report released last week the National Academy of Sciences' Panel on Scientific Communication and National Security concluded that the ‘limited and uncertain benefits’ of controls on the dissemination of scientific and technological research are ‘outweighed by the importance of scientific progress, which open communication accelerates, to the overall welfare of the nation.’ The 18-member panel, chaired by Dale R. Corson, president emeritus of Cornell University, was created last spring (Eos, April 20, 1982, p. 241) to examine the delicate balance between open dissemination of scientific and technical information and the U.S. government's desire to protect scientific and technological achievements from being translated into military advantages for our political adversaries.The panel dealt almost exclusively with the relationship between the United States and the Soviet Union but noted that there are ‘clear problems in scientific communication and national security involving Third World countries.’ Further study of this matter is necessary.

  5. Undergraduate honors students' images of science: Nature of scientific work and scientific knowledge

    Science.gov (United States)

    Wallace, Michael L.

    This exploratory study assessed the influence of an implicit, inquiry-oriented nature of science (NOS) instructional approach undertaken in an interdisciplinary college science course on undergraduate honor students' (UHS) understanding of the aspects of NOS for scientific work and scientific knowledge. In this study, the nature of scientific work concentrated upon the delineation of science from pseudoscience and the value scientists place on reproducibility. The nature of scientific knowledge concentrated upon how UHS view scientific theories and how they believe scientists utilize scientific theories in their research. The 39 UHS who participated in the study were non-science majors enrolled in a Honors College sponsored interdisciplinary science course where the instructors took an implicit NOS instructional approach. An open-ended assessment instrument, the UFO Scenario, was designed for the course and used to assess UHS' images of science at the beginning and end of the semester. The mixed-design study employed both qualitative and quantitative techniques to analyze the open-ended responses. The qualitative techniques of open and axial coding were utilized to find recurring themes within UHS' responses. McNemar's chi-square test for two dependent samples was used to identify whether any statistically significant changes occurred within responses from the beginning to the end of the semester. At the start of the study, the majority of UHS held mixed NOS views, but were able to accurately define what a scientific theory is and explicate how scientists utilize theories within scientific research. Postinstruction assessment indicated that UHS did not make significant gains in their understanding of the nature of scientific work or scientific knowledge and their overall images of science remained static. The results of the present study found implicit NOS instruction even with an extensive inquiry-oriented component was an ineffective approach for modifying UHS

  6. Personality Profiles of Cultures: Aggregate Personality Traits

    Czech Academy of Sciences Publication Activity Database

    McCrae, R.R.; Terracciano, A.; Leibovich, N.B.; Schmidt, V.; Shakespeare-Finch, J.; Neubauer, A.; De Fruyt, F.; Munyae, M.; Flores-Mendoza, C.; Dahourou, D.; Ayearst, L. E.; Trobst, K.K.; Alcalay, L.; Simonetti, F.; Bratko, D.; Marušic´, I.; Hřebíčková, Martina; Mortensen, L.K.; Jensen, H.H.; Allik, J.; Realo, A.; Sineshaw, T.; Rolland, J-P.; Petot, J.M.; Camart, N.; Angleitner, A.; Ostendorf, F.; Yik, M.; Jónsson, F. H.; Pramila, V.S.; Halim, M. S.; Jaya, A.; Shahriar Shahidi, S.; Barbaranelli, C.; Shimonaka, Y.; Gakuin, B.; Nakazato, K.; Abdel Khalek, A. M.; Alansari, B. M.; Khoury, B.; Mastor, K.A.; Falzon, R.; Lauri, M.A.; Borg Cunen, M.A.; Scicluna Calleja, S.; Diaz-Loving, R.; Ghayur, M. A.; Fischer, R.; Oluyinka Ojedokun, A.; Prentice, G.; McRorie, M.; Wang, L.; Reátegui, N.; Brunner-Sciarra, M.; del Pilar, G.E.H.; Sekowski, A.; Klinkosz, W.; Pedroso de Lima, M.; Porrata, J.; Martin, T.A.; Ficková, E.; Adamovová, L.; Rus, V.R.; Podobnik, N.; Zupancic, A.; Ahn, H.; Ahn, Ch.; Avia, M. D.; Sánchez-Bernardos, M.L.; Ruch, W.; Rossier, J.; Chittcharat, N.; Gülgöz, S.; Nansubuga, F.; Smith, P.B.; Matsumoto, D.; Diener, E.; Beer, A.; Humrichouse, J.; Budzinski, L.; Oishi, S.; Knežević, G.; Djuric Jocic, D.

    2005-01-01

    Roč. 89, č. 3 (2005), s. 407-425 ISSN 0022-3514 R&D Projects: GA ČR GA406/01/1507 Institutional research plan: CEZ:AV0Z70250504 Keywords : personality * five-factor model * cross - cultural * culture-level analyses * culture profiles Subject RIV: AN - Psychology Impact factor: 4.211, year: 2005

  7. Mixing height measurements from UHF wind profiling radar

    Energy Technology Data Exchange (ETDEWEB)

    Angevine, W.M.; Grimsdell, A.W. [CIRES, Univ. of Colorado, and NOAA Aeronomy Lab., Boulder, Colorado (United States)

    1997-10-01

    Mixing height in convective boundary layers can be detected by wind profiling radars (profilers) operating at or near 915 MHZ. We have made such measurements in a variety of settings including Alabama in 1992; Nova Scotia, Canada, during the North Atlantic Regional Experiment (NARE) 1993; Tennessee during the Southern Oxidant Study (SOS) 1994; near a 450 m tower in Wisconsin in 1995; and extensively in Illinois during the Flatland95, `96, and `97 experiments, as well as continuous operations at the Flatland Atmospheric Observatory. Profiler mixing height measurements, like all measurements, are subject to some limitations. The most important of these are due to rainfall, minimum height, and height resolution. Profilers are very sensitive to rain, which dominates the reflectivity and prevents the mixing height from being detected. Because the best height resolution is currently 60 m and the minimum height is 120-150 m AGL, the profiler is not suited for detecting mixing height in stable or nocturnal boundary layers. Problems may also arise in very dry or cold environments. (au) 12 refs.

  8. WWW: The Scientific Method

    Science.gov (United States)

    Blystone, Robert V.; Blodgett, Kevin

    2006-01-01

    The scientific method is the principal methodology by which biological knowledge is gained and disseminated. As fundamental as the scientific method may be, its historical development is poorly understood, its definition is variable, and its deployment is uneven. Scientific progress may occur without the strictures imposed by the formal…

  9. Mining the literature: new methods to exploit keyword profiles

    OpenAIRE

    Andrade-Navarro, Miguel A

    2012-01-01

    Bibliographic records in the PubMed database of biomedical literature are annotated with Medical Subject Headings (MeSH) by curators, which summarize the content of the articles. Two recent publications explain how to generate profiles of MeSH terms for a set of bibliographic records and to use them to define any given concept by its associated literature. These concepts can then be related by their keyword profiles, and this can be used, for example, to detect new associations between genes ...

  10. The Scientific Enterprise

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 13; Issue 9. The Scientific Enterprise - Assumptions, Problems, and Goals in the Modern Scientific Framework. V V Raman. Reflections Volume 13 Issue 9 September 2008 pp 885-894 ...

  11. Science and Scientific Curiosity in Pre-school—The teacher's point of view

    Science.gov (United States)

    Spektor-Levy, Ornit; Kesner Baruch, Yael; Mevarech, Zemira

    2013-09-01

    Nowadays, early science education is well-accepted by researchers, education professionals and policy makers. Overall, teachers' attitudes and conceptions toward the science subject domain and science education influence their ways of teaching and engagement. However, there is a lack of research regarding factors that affect this engagement in pre-school years. The main assumption of this study is that teachers' attitudes regarding science in pre-school can shape children's engagement in science and develop their scientific curiosity. Therefore, the main objectives of this study are to investigate the attitudes of pre-school teachers toward engaging in science and to explore their views about the nature of curiosity: who is a curious child and how can a child's natural curiosity be fostered? An extensive survey was conducted among 146 pre-school teachers by employing both qualitative and quantitative approaches. Results indicate that most of the participants believe that scientific education should begin in early childhood; very young children can investigate and take part in a process of inquiry; and scientific activities in pre-school can influence children's long-term attitudes toward science. Despite these views, most participants felt they did not possess sufficient scientific knowledge. Furthermore, participants expressed diverse opinions when asked to identify what constitutes curiosity, how the curious child can be identified and how a child's curiosity can be fostered. The research findings carry significant implications regarding how to implement scientific activities in pre-school, and how to encourage pre-school teachers to engage children in scientific activities in a way that will nurture their natural curiosity.

  12. Building visual identity of scientific and research units and the role of visualization in cooperation with business

    Directory of Open Access Journals (Sweden)

    Alfreda Kamińska

    2014-12-01

    Full Text Available The need for commercialization of scientific research leads to the necessity of changing the orientation of scientific-research units to marketing orientation, which is characterized by, among others, conducting research aimed at learning the clients’ needs and building better communication with the recipients. What is an important element of a unit’s marketing communication is its visual identity system, which the recipients use to build their opinion and their picture of the unit. The goal of this article is an attempt to define the key rules of designing visual identity of scientific and research institutions, as well as presenting the role of visualization in their cooperation with business. In the article the notions of image, identity, corporate identity and visual identity are subject to analysis. The article also presents the significance of visualization in the functioning of research and scientific units, elements of visual identity system and the rules of designing visual identity of scientific and research institutions. An analysis of chosen research-scientific units was carried out with regard to visualization.

  13. Fostering Scientific Literacy: Establishing Social Relevance via the Grand Challenges

    Science.gov (United States)

    Lyford, M. E.; Myers, J. D.; Buss, A.

    2010-12-01

    Numerous studies and polls suggest the general public’s understanding of science and scientific literacy remain woefully inadequate despite repeated calls for improvement over the last 150 years. This inability to improve scientific literacy significantly is a complex problem likely driven by a number of factors. However, we argue that past calls and efforts for improving scientific literacy have failed to: 1) articulate a truly meaningful justification for society to foster a scientifically literate public; 2) provide a rationale that motivates individuals of diverse backgrounds to become scientifically literate; 3) consider the impact of personal perspective, e.g. values, beliefs, attitudes, etc., on learning; and 4) offer a relevant and manageable framework in which to define scientific literacy. For instance, past calls for improving scientific literacy, e.g. the U.S. is behind the Soviets in the space race, U.S students rank below country X in math and science, etc., have lacked justification, personal motivation and a comprehensive framework for defining scientific literacy. In these cases, the primary justification for improving science education and scientific literacy was to regain international dominance in the space race or to advance global standing according to test results. These types of calls also articulate short-term goals that are rendered moot once they have been achieved. At the same time, teaching practices have commonly failed to consider the perspectives students bring to the classroom. Many STEM faculty do not address issues of personal perspective through ignorance or the desire to avoid controversial subjects, e g. evolution, climate change. We propose that the ‘grand challenges’ (e.g., energy, climate change, antibacterial resistance, water, etc.) humankind currently faces provides a compelling framework for developing courses and curricula well-suited for improving scientific literacy. A grand challenge paradigm offers four

  14. Voice recognition software can be used for scientific articles.

    Science.gov (United States)

    Pommergaard, Hans-Christian; Huang, Chenxi; Burcharth, Jacob; Rosenberg, Jacob

    2015-02-01

    Dictation of scientific articles has been recognised as an efficient method for producing high-quality, first article drafts. However, standardised transcription service by a secretary may not be available for all researchers and voice recognition software (VRS) may therefore be an alternative. The purpose of this study was to evaluate the out-of-the-box accuracy of VRS. Eleven young researchers without dictation experience dictated the first draft of their own scientific article after thorough preparation according to a pre-defined schedule. The dictate transcribed by VRS was compared with the same dictate transcribed by an experienced research secretary, and the effect of adding words to the vocabulary of the VRS was investigated. The number of errors per hundred words was used as outcome. Furthermore, three experienced researchers assessed the subjective readability using a Likert scale (0-10). Dragon Nuance Premium version 12.5 was used as VRS. The median number of errors per hundred words was 18 (range: 8.5-24.3), which improved when 15,000 words were added to the vocabulary. Subjective readability assessment showed that the texts were understandable with a median score of five (range: 3-9), which was improved with the addition of 5,000 words. The out-of-the-box performance of VRS was acceptable and improved after additional words were added. Further studies are needed to investigate the effect of additional software accuracy training.

  15. History of artificial cold, scientific, technological and cultural issues

    CERN Document Server

    2014-01-01

    The history of artificial cold has been a rather intriguing interdisciplinary subject (physics, chemistry, technology, sociology, economics, anthropology, consumer studies) which despite some excellent monographs and research papers, has not been systematically exploited. It is a subject with all kinds of scientific, technological as well as cultural dimensions. For example, the common home refrigerator has brought about unimaginably deep changes to our everyday lives changing drastically eating habits and shopping mentalities. From the end of the 19th century to the beginning of the 21st, issues related to the production and exploitation of artificial cold have never stopped to provide us with an incredibly interesting set of phenomena, novel theoretical explanations, amazing possibilities concerning technological applications and all encompassing cultural repercussions. The discovery of the unexpected and “bizarre” phenomena of superconductivity and superfluidity, the necessity to incorporate macroscopi...

  16. Using Rubrics as a Scientific Writing Instructional Method in Early Stage Undergraduate Neuroscience Study.

    Science.gov (United States)

    Clabough, Erin B D; Clabough, Seth W

    2016-01-01

    Scientific writing is an important communication and learning tool in neuroscience, yet it is a skill not adequately cultivated in introductory undergraduate science courses. Proficient, confident scientific writers are produced by providing specific knowledge about the writing process, combined with a clear student understanding about how to think about writing (also known as metacognition). We developed a rubric for evaluating scientific papers and assessed different methods of using the rubric in inquiry-based introductory biology classrooms. Students were either 1) given the rubric alone, 2) given the rubric, but also required to visit a biology subject tutor for paper assistance, or 3) asked to self-grade paper components using the rubric. Students who were required to use a peer tutor had more negative attitudes towards scientific writing, while students who used the rubric alone reported more confidence in their science writing skills by the conclusion of the semester. Overall, students rated the use of an example paper or grading rubric as the most effective ways of teaching scientific writing, while rating peer review as ineffective. Our paper describes a concrete, simple method of infusing scientific writing into inquiry-based science classes, and provides clear avenues to enhance communication and scientific writing skills in entry-level classes through the use of a rubric or example paper, with the goal of producing students capable of performing at a higher level in upper level neuroscience classes and independent research.

  17. Bio-medicolegal scientific research in Europe. A country-based analysis.

    Science.gov (United States)

    Viel, Guido; Boscolo-Berto, Rafael; Cecchi, Rossana; Bajanowski, Thomas; Vieira, Nuno Duarte; Ferrara, Santo Davide

    2011-09-01

    The European mosaic of socio-cultural, economic and legal realities is reflected in forensic and legal medicine, in which a great variety of operational modes of forensic medical services, organisational systems, structures, functional competences and scientific research strategies can be observed. The present work analyses the European bio-medicolegal scientific output of the last 5.5 years (exact time window, January 1, 2005-June 1, 2010), categorising papers by nationality of the corresponding author and forensic sub-discipline in question, in order to identify the peculiarities of national sub-specialised competences and to build up international research projects. This country-based bibliometric analysis, based on the number of articles and the impact factor produced by each European country, also considering its economic profile (gross domestic product and per capita gross domestic product), highlights the prevailing productive role of Western and Southern Europe (Germany, Great Britain, Italy, Switzerland, Spain and France). Categorising scientific output by forensic sub-discipline and branch, significant in terms of impact factor are contributions from Germany (coming first in Pathology, Toxicology, Genetics, Anthropology and Biological Criminalistics), Great Britain (first in Clinical Forensic Medicine, Malpractice and Invalidity-Social Insurance), Switzerland (first in Criminology), Italy (second in Toxicology, Anthropology and Invalidity-Social Insurance), The Netherlands (third in Clinical Forensic Medicine and Medical Law and Ethics), Spain (third in Genetics, Criminalistics and Invalidity-Social Insurance) and France (third in Toxicology and Malpractice). Interestingly, several countries with low gross domestic product, such as Poland, Turkey and other Eastern European nations, show notable scientific production in specific sub-disciplines such as Pathology, Toxicology and Forensic Genetics, suggesting that fruitful international cooperation could be

  18. Evolution of the scientific paper

    Energy Technology Data Exchange (ETDEWEB)

    Harmon, J.E.

    1992-09-01

    The first papers reporting original research results in technical periodicals and proceedings appeared in the late 17th century. Since that time, the typical scientific paper has evolved from a fairly simple document, accessible to a general audience, to a much more complex one, aimed at a specialized audience. The purpose of this article is to give an overview of what the first scientific papers were like and how they evolved to their present form and style. To facilitate this discussion, the scientific paper`s development has arbitrarily been divided into four stages: the origin and formative years of the scientific paper (1665-1765), emergence of scientific papers written for specialized publications (1765-1865), development of the modem scientific paper (1865-1965), and hyperspecialization and computerization of the modem scientific paper (1965-?).

  19. Evolution of the scientific paper

    Energy Technology Data Exchange (ETDEWEB)

    Harmon, J.E.

    1992-01-01

    The first papers reporting original research results in technical periodicals and proceedings appeared in the late 17th century. Since that time, the typical scientific paper has evolved from a fairly simple document, accessible to a general audience, to a much more complex one, aimed at a specialized audience. The purpose of this article is to give an overview of what the first scientific papers were like and how they evolved to their present form and style. To facilitate this discussion, the scientific paper's development has arbitrarily been divided into four stages: the origin and formative years of the scientific paper (1665-1765), emergence of scientific papers written for specialized publications (1765-1865), development of the modem scientific paper (1865-1965), and hyperspecialization and computerization of the modem scientific paper (1965- ).

  20. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to very low calorie diets (VLCDs) and reduction in body weight (ID 1410), reduction in the sense of hunger (ID 1411), reduction in body fat mass while maintaining lean

    DEFF Research Database (Denmark)

    Tetens, Inge

    claims in relation to very low calorie diets (VLCDs) and reduction in body weight, reduction in the sense of hunger, reduction in body fat mass while maintaining lean body mass, reduction of post-prandial glycaemic responses, and maintenance of normal blood lipid profile. The scientific substantiation...... that whereas the diet that is the subject of the claim, very low calorie diet, is sufficiently characterised in relation to the following claimed effects: reduction in body weight (ID 1410), reduction in the sense of hunger (ID 1411), and reduction in body fat mass while maintaining lean body mass (ID 1412...... that formula foods for use in very low calorie diets should contain. The Panel concludes that a cause and effect relationship cannot be established between the consumption of a very low calorie diet and reduction of post-prandial glycaemic responses (ID 1414) and maintenance of normal blood lipid profile (ID...

  1. The scientific production in periodic institucional: study of the journal biblos

    Directory of Open Access Journals (Sweden)

    João Paulo Borges Silveira

    2012-04-01

    Full Text Available This article discusses the scientific communication through scientific journals institutional, based on a study of Journal Biblos, journal linked to the Institute of the Humanities Sciences and the Information (ICHI, Federal University of the Rio Grande (FURG. To search delimit the period of circulation the magazine between 1978 and 2009, 31 years of activity, accounting for 32 fascicles and 392 articles published. The research aimed to define the profile of authors who published articles in the magazine and to identify the themes of articles published, following the knowledge areas stipulated. The methodological procedure used was bibliometrics, and from their results, they were analyzed under a bias quantitatively and qualitatively. Among the survey results identified that the authors are most doctorate by the magazine as well as there searchers linked FURG, although the authors with higher productivity in the magazine are part of the university teachers’. Among the topics of articles, History has an absolute majority of published papers with 67% of the total, followed by Applied Social Sciences I, which fits the area of information Science.

  2. European Union research in support of environment and health: Building scientific evidence base for policy.

    Science.gov (United States)

    Karjalainen, Tuomo; Hoeveler, Arnd; Draghia-Akli, Ruxandra

    2017-06-01

    Opinion polls show that the European Union citizens are increasingly concerned about the impact of environmental factors on their health. In order to respond and provide solid scientific evidence for the numerous policies related to the protection of human health and the environment managed at the Union level, the European Union made a substantial investment in research and innovation in the past two decades through its Framework Programmes for Research and Technological Development, including the current programme, Horizon 2020, which started in 2014. This policy review paper analysed the portfolio of forty collaborative projects relevant to environment and health, which received a total amount of around 228 million euros from the EU. It gives details on their contents and general scientific trends observed, the profiles of the participating countries and institutions, and the potential policy implications of the results obtained. The increasing knowledge base is needed to make informed policy decisions in Europe and beyond, and should be useful to many stakeholders including the scientific community and regulatory authorities. Copyright © 2017. Published by Elsevier Ltd.

  3. Considerations of education in the field of biophotonics in engineering: the experience of the subject fundamentals of biophotonics

    Science.gov (United States)

    Fanjul-Vélez, F.; Arce-Diego, J. L.

    2017-12-01

    Education in the field of photonics is usually somehow complex due to the fact that most of the programs include just a few subjects on the field, apart from specific Master programs in Photonics. There are also specific doctorate programs dealing with photonics. Apart from the problems shared with photonics in education in general, biophotonics specifically needs an interdisciplinary approach between biomedical and technical or scientific fields. In this work, we present our education experience in teaching the subject Fundamentals of Biophotonics, intended preferentially to engineering Bachelor and Master degrees students, but also to science and medicine students. First it was necessary to join a teaching group coming from the scientific technical and medical fields, working together in the subject. This task was easier as our research group, the Applied Optical Techniques group, had previous contacts and experience in working with medicine professors and medical doctors at hospitals. The orientation of the subject, intended for both technical and medical students, has to be carefully selected. All this information could be employed by other education institutions willing to implement studies on biomedical optics.

  4. Burnout, work engagement and workaholism among highly educated employees: Profiles, antecedents and outcomes

    Directory of Open Access Journals (Sweden)

    Hely Innanen

    2014-06-01

    Full Text Available The present study examined the longitudinal profiles of burnout, engagement and workaholism among highly educated employees. First, the latent profile modeling indicated two latent classes: Engaged and Exhausted-Workaholic. Second, the results revealed that employees with the Engaged profile experienced high levels of energy and dedication, whereas employees with the Exhausted-Workaholic profile experienced exhaustion, cynicism and workaholism. Social pessimism in the transition from high education to work predicted poor subjective well-being at work. Further, workaholism decreased during the career among members of the Exhausted-Workaholic profile suggesting positive direction during career. Finally, Engaged employees experienced detachment and relaxation, life satisfaction and rewards.

  5. Issues concerning scientific production of including people with disabilities at work.

    Science.gov (United States)

    Guimarães, B M; Martins, L B; Barkokébas Junior, B

    2012-01-01

    This article presents the results of a survey carried out on leading periodicals in the areas of Ergonomics, Physiotherapy and Occupational Therapy, the aim of which was to identify scientific publications on the inclusion at work of people with disabilities. The survey of articles published on this topic in the following journals was conducted in December 2010: Applied Ergonomics, Ergonomics, the International Journal of Industrial Ergonomics, Disability and Rehabilitation, and the Journal of Occupational Rehabilitation. The survey covered issues published between 2000 and 2010 and was conducted electronically using the CAPES Periodicals Portal. To collect the articles, it was necessary to check the articles published in each of the issues of each volume of these periodicals. This is how the articles on the topic in question were found. There were 27 articles on the topic of inclusion at work of people with disabilities, of which 13 were published in the Journal of Occupational Rehabilitation and 12 in Disability and Rehabilitation. Thus, it is clear that the issue in question is still a subject that is seldom dealt with in these publications and it is noted that only two articles were published in Ergonomics journals in this period, thus confirming the paucity of scientific publications on this subject.

  6. Impact of Minnesota's "Profile of Learning"

    Directory of Open Access Journals (Sweden)

    Patricia G. Avery

    2003-02-01

    Full Text Available In 1990, the Minnesota State Board of Education declared its intention to develop a "results-oriented graduation requirement" based on student achievement as opposed to the usual credit/course completion requirement. In addition to a traditional test of basic skills, the state began developing the Profile of Learning, a set of performance-based standards grounded in a constructivist educational philosophy, an approach that differs from the content-based standards found in many states. The Profile was controversial from its inception. Conservatives characterized the Profile as too process- oriented and as lacking subject-matter content; teachers reported that the Profile required a significant amount of additional teacher preparation time; and parents, who were not adequately informed about the Profile, questioned the purpose of the Profile. Teachers were frustrated with the confusing and sometimes contradictory directions they received from the Minnesota Department of Children, Families, and Learning charged with implementing the Profile. In 2000-2001, we surveyed and interviewed selected secondary English and social studies teachers in the state about their perceptions of the Profile’s impact on teaching and learning. Among the positive perceptions was an increase in students’ higher order thinking, students’ understanding of criteria for quality work, and teachers conversations with one another about instructional issues. Increased teacher preparation time and decreased enjoyment of teaching were among the negative perceptions. Teachers also experienced difficulty adopting performance assessment techniques. When teachers believed they received effective preparation and adequate resources for working with the Profile, they were much more likely to report beneficial effects in terms of teaching and learning. The majority of teachers, however, rated their preparation and resources as "fair" or "poor." Results are discussed in terms of

  7. Turning Scientific Presentations into Stories

    Science.gov (United States)

    Aruffo, Christopher

    2015-01-01

    To increase students' confidence in giving scientific presentations, students were shown how to present scientific findings as a narrative story. Students who were preparing to give a scientific talk attended a workshop in which they were encouraged to experience the similarities between telling a personal anecdote and presenting scientific data.…

  8. The Effects of Body Acupuncture on Obesity: Anthropometric Parameters, Lipid Profile, and Inflammatory and Immunologic Markers

    Directory of Open Access Journals (Sweden)

    Hamid Abdi

    2012-01-01

    Full Text Available A randomized controlled clinical trial in 196 obese subjects was performed to examine the effectiveness of body acupuncture on body weight loss, lipid profile and immunogenic and inflammatory markers. Subjects received authentic (cases or sham (controls acupuncture for 6 weeks in combination with a low-calorie diet. In the following 6 weeks, they received the low-calorie diet alone. Subjects were assessed at the beginning, 6 and 12 weeks later. Heat shock protein (Hsps-27, 60, 65, 70 antibody titers and high sensitivity C-reactive protein (hs-CRP levels were also assessed. A significant reduction in measures of adiposity and improvement in lipid profile were observed in both groups, but the levels of anti-Hsp-antibodies decreased in cases only. A reduction in anthropometric and lipid profile in cases were sustained in the second period, however, only changes in lipid profile were observed in the control group. Anti-Hsp-antibodies and hs-CRP levels continued to be reduced in cases but in controls only the reduction in hs-CRP remained. Changes in anthropometric parameters, lipid profile, and anti-Hsp-antibodies were more evident in cases. Body acupuncture in combination with diet restriction was effective in enhancing weight loss and improving dyslipidemia.

  9. The Effects of Body Acupuncture on Obesity: Anthropometric Parameters, Lipid Profile, and Inflammatory and Immunologic Markers

    Science.gov (United States)

    Abdi, Hamid; Zhao, Baixiao; Darbandi, Mahsa; Ghayour-Mobarhan, Majid; Tavallaie, Shima; Rahsepar, Amir Ali; Parizadeh, Seyyed Mohammad Reza; Safariyan, Mohammad; Nemati, Mohsen; Mohammadi, Maryam; Abbasi-Parizad, Parisa; Darbandi, Sara; Akhlaghi, Saeed; Ferns, Gordon A. A.

    2012-01-01

    A randomized controlled clinical trial in 196 obese subjects was performed to examine the effectiveness of body acupuncture on body weight loss, lipid profile and immunogenic and inflammatory markers. Subjects received authentic (cases) or sham (controls) acupuncture for 6 weeks in combination with a low-calorie diet. In the following 6 weeks, they received the low-calorie diet alone. Subjects were assessed at the beginning, 6 and 12 weeks later. Heat shock protein (Hsps)-27, 60, 65, 70 antibody titers and high sensitivity C-reactive protein (hs-CRP) levels were also assessed. A significant reduction in measures of adiposity and improvement in lipid profile were observed in both groups, but the levels of anti-Hsp-antibodies decreased in cases only. A reduction in anthropometric and lipid profile in cases were sustained in the second period, however, only changes in lipid profile were observed in the control group. Anti-Hsp-antibodies and hs-CRP levels continued to be reduced in cases but in controls only the reduction in hs-CRP remained. Changes in anthropometric parameters, lipid profile, and anti-Hsp-antibodies were more evident in cases. Body acupuncture in combination with diet restriction was effective in enhancing weight loss and improving dyslipidemia. PMID:22649299

  10. Designing a Secure Storage Repository for Sharing Scientific Datasets using Public Clouds

    Energy Technology Data Exchange (ETDEWEB)

    Kumbhare, Alok [Univ. of Southern California, Los Angeles, CA (United States); Simmhan, Yogesth [Univ. of Southern California, Los Angeles, CA (United States); Prasanna, Viktor [Univ. of Southern California, Los Angeles, CA (United States)

    2011-11-14

    As Cloud platforms gain increasing traction among scientific and business communities for outsourcing storage, computing and content delivery, there is also growing concern about the associated loss of control over private data hosted in the Cloud. In this paper, we present an architecture for a secure data repository service designed on top of a public Cloud infrastructure to support multi-disciplinary scientific communities dealing with personal and human subject data, motivated by the smart power grid domain. Our repository model allows users to securely store and share their data in the Cloud without revealing the plain text to unauthorized users, the Cloud storage provider or the repository itself. The system masks file names, user permissions and access patterns while providing auditing capabilities with provable data updates.

  11. Study of the comprehension of the scientific method by members of a university health research laboratory.

    Science.gov (United States)

    Burlamaque-Neto, A C; Santos, G R; Lisbôa, L M; Goldim, J R; Machado, C L B; Matte, U; Giugliani, R

    2012-02-01

    In Brazil, scientific research is carried out mainly at universities, where professors coordinate research projects with the active participation of undergraduate and graduate students. However, there is no formal program for the teaching/learning of the scientific method. The objective of the present study was to evaluate the comprehension of the scientific method by students of health sciences who participate in scientific projects in an academic research laboratory. An observational descriptive cross-sectional study was conducted using Edgar Morin complexity as theoretical reference. In a semi-structured interview, students were asked to solve an abstract logical puzzle - TanGram. The collected data were analyzed using the hermeneutic-dialectic analysis method proposed by Minayo and discussed in terms of the theoretical reference of complexity. The students' concept of the scientific method is limited to participation in projects, stressing the execution of practical procedures as opposed to scientific thinking. The solving of the TanGram puzzle revealed that the students had difficulties in understanding questions and activities focused on subjects and their processes. Objective answers, even when dealing with personal issues, were also reflected on the students' opinions about the characteristics of a successful researcher. Students' difficulties concerning these issues may affect their scientific performance and result in poorly designed experiments. This is a preliminary study that should be extended to other centers of scientific research.

  12. Software support for students engaging in scientific activity and scientific controversy

    Science.gov (United States)

    Cavalli-Sforza, Violetta; Weiner, Arlene W.; Lesgold, Alan M.

    Computer environments could support students in engaging in cognitive activities that are essential to scientific practice and to the understanding of the nature of scientific knowledge, but that are difficult to manage in science classrooms. The authors describe a design for a computer-based environment to assist students in conducting dialectical activities of constructing, comparing, and evaluating arguments for competing scientific theories. Their choice of activities and their design respond to educators' and theorists' criticisms of current science curricula. They give detailed specifications of portions of the environment.

  13. Scientific Research Competencies of Prospective Teachers and their Attitu des toward Scientific Research

    Directory of Open Access Journals (Sweden)

    Hasan Hüseyin Şahan

    2015-09-01

    Full Text Available Present study has been constructed to determine scientific research competencies of prospective teachers and identify the extent of effect of prospective teachers’ attitudes toward scientific research and scientific research methods course on their research skills and attitudes towards research. This study has two dimensions: it is a descriptive study by virtue of identifying prospective teachers’ research skills and attitudes toward research, also an experimental study by virtue of determining the effect of scientificresearch methods course on prospective teachers’ skills and their attitudes toward research. In order to obtain the data related to identified sub-problems “Scale for Identifying Scientific Research Competencies” and “Scale for Identifying the Attitude toward Research” have been utilized. Data collection tools were applied to 445 prospective teachers. It has thus been concluded in this study that scientific research methods course had no significant effect in gaining scientific research competencies to prospective teachers and that this effect demonstrated no differentiation with respect to departments. On the other hand it has been explored that scientific research methods course had a negative effect onthe attitudes of prospective teachers toward research and that there was a differentiation to the disadvantage of prospective teachers studying at Primary Education Mathematics Teaching Department.

  14. The clinical utility of lipid profile and positive troponin in predicting future cardiac events

    Directory of Open Access Journals (Sweden)

    Arun Kumar

    2012-02-01

    Full Text Available Objective: To study the usefulness of traditional lipid profile levels in screening subjects who had developed chest pain due to cardiac event as indicated by a positive troponin I (TnI test. Methods: In this retrospective study data of the 740 patients presented to the emergency department with symptoms of cardiac ischemia that underwent both troponin and lipid profiles tests were compared with the lipid profiles of 411 normal healthy subjects (controls. The troponin was detected qualitatively when a specimen contains TnI above the 99th percentile (TnI >0.5 ng/ mL. The total cholesterol (TC, high density lipoproteins (HDL, very low density lipoproteins (VLDL, and triacyl glycerol (TG levels were also analyzed and low density lipoprotein level (LDL was calculated using Friedewald ’s formula. Results: Patients with chest pain and positive troponin test (with confirmed cardiac event were found to have significantly elevated levels of TC, TG, LDL and significantly reduced HDL levels when compared to the patients who experienced only chest pain (negative troponin and healthy controls. Conclusions: Traditional lipid profile levels still can be used in screening populations to identify the subjects with high risk of developing cardiac event which is identified by highly sensitive and specific positive troponin test.

  15. Melatonin and cortisol profiles in the absence of light perception

    DEFF Research Database (Denmark)

    Aubin, S.; Kupers, R.; Ptito, M.

    2017-01-01

    As light plays an important role in the synchronisation of the internal biological clock to the environmental day/night schedule, we compared the 24-h profiles of biological circadian markers in blind and normal sighted individuals. Salivary melatonin and cortisol concentrations were collected...... every two hours in eleven blind subjects, reporting no conscious light perception, and eleven age- and sex-matched normal sighted controls. Timing of melatonin onset and associated cortisol quiescence period confirm an increased incidence of abnormal circadian patterns in blindness. Additionally, blind...... subjects showed a greater overall melatonin concentration throughout the 24-h period. Cortisol profiles, including concentration and morning cortisol peaks, on the other hand, did not differ between blind and sighted individuals. These findings support previous reports of an increase in abnormal circadian...

  16. A clinical and biochemical profile of biopsy-proven non-alcoholic fatty liver disease subjects

    International Nuclear Information System (INIS)

    Khurram, M.; Mushraf, M.

    2007-01-01

    To describe clinical and biochemical features of patients with biopsy-proven non-alcoholic fatty liver disease (NAFLD). Fifty patients of either and of all ages were included, who had ultrasound evidence of fatty liver, deranged liver enzymes, and negative history of alcohol uptake. Serological/biochemical tests/markers of other liver diseases were negative. Each subject underwent liver biopsy reported by a single histopathologist. Clinical (symptoms, hypertension, hepatomegaly, and obesity) and biochemical evaluation (for diabetes, lipid abnormalities, and aspartate to alanine aminotransferase ratio (AST/ALT)) of each subject was done. Chi-square and t-tests were used for p-value calculation for finding significant difference between fatty liver and non-alcoholic steato-hepatitis groups. Thirty three (66%) patients were female and 34% were male. Mean age was 45.50+-11.50 years. Histopathologically, 62% subjects had fatty liver alone, while 38% had nonalcoholic steatohepatitis (NASH). Fatigue (100%), hypertriglyceridemia (80%), hepatomegaly (72%), AST/ALT ratio <1 (72%), and obesity/overweight (54%) were common NAFLD-related features. Except for hypertriglycedemia (p-value 0.008), no statistically significant association was noted between these features and histopathological subtypes of NAFLD. NAFLD-related clinical and biochemical features included fatigue, obesity, hepatomegaly, AST/ALT ratio <1, and hypertriglycedemia. Significant relationship existed between hypertriglyceridemia and NASH. (author)

  17. Applied and numerical partial differential equations scientific computing in simulation, optimization and control in a multidisciplinary context

    CERN Document Server

    Glowinski, R; Kuznetsov, Y A; Periaux, Jacques; Neittaanmaki, Pekka; Pironneau, Olivier

    2010-01-01

    Standing at the intersection of mathematics and scientific computing, this collection of state-of-the-art papers in nonlinear PDEs examines their applications to subjects as diverse as dynamical systems, computational mechanics, and the mathematics of finance.

  18. Centrifuge-Simulated Suborbital Spaceflight in a Subject with Cardiac Malformation.

    Science.gov (United States)

    Blue, Rebecca S; Blacher, Eric; Castleberry, Tarah L; Vanderploeg, James M

    2015-11-01

    Commercial spaceflight participants (SFPs) will introduce new medical challenges to the aerospace community, with unique medical conditions never before exposed to the space environment. This is a case report regarding the response of a subject with multiple cardiac malformations, including aortic insufficiency, pulmonary atresia, pulmonary valve replacement, ventricular septal defect (post-repair), and pulmonary artery stenosis (post-dilation), to centrifuge acceleration simulating suborbital flight. A 23-yr-old man with a history of multiple congenital cardiac malformations underwent seven centrifuge runs over 2 d. Day 1 consisted of two +G(z) runs (peak = +3.5 G(z), run 2) and two +G(x) runs (peak = +6.0 G(x), run 4). Day 2 consisted of three runs approximating suborbital spaceflight profiles (combined +G(x) and +G(z)). Data collected included blood pressure, electrocardiogram, pulse oximetry, neurovestibular exams, and post-run questionnaires regarding motion sickness, disorientation, greyout, and other symptoms. Despite the subject's significant medical history, he tolerated the acceleration profiles well and demonstrated no significant abnormal physiological responses. Potential risks to SFPs with aortic insufficiency, artificial heart valves, or valvular insufficiency include lower +G(z) tolerance, earlier symptom onset, and ineffective mitigation strategies such as anti-G straining maneuvers. There are no prior studies of prolonged accelerations approximating spaceflight in such individuals. This case demonstrates tolerance of acceleration profiles in an otherwise young and healthy individual with significant cardiac malformations, suggesting that such conditions may not necessarily preclude participation in commercial spaceflight.

  19. Risk as economic category: systematics scientific approach and refinement contents

    OpenAIRE

    V.G. Vygovskyy

    2015-01-01

    The paper studies the categorical-conceptual apparatus of risk and its refinement based on a critical analysis of existing systematic scientific approaches. Determined that in the refinement of the economic nature of the risk of a number of controversial issues: the definition of the objective or subjective nature of risk; matching of concepts such as «risk», «danger», «loss», «probability of loss»; definition of negative or positive consequences of risk; identification of risk with its conse...

  20. Effects of Outdoor School Ground Lessons on Students' Science Process Skills and Scientific Curiosity

    Science.gov (United States)

    Ting, Kan Lin; Siew, Nyet Moi

    2014-01-01

    The purpose of this study was to investigate the effects of outdoor school ground lessons on Year Five students' science process skills and scientific curiosity. A quasi-experimental design was employed in this study. The participants in the study were divided into two groups, one subjected to the experimental treatment, defined as…

  1. Mitigating climate change by sequestering carbon soils: A hypertext-based scientific assessment

    International Nuclear Information System (INIS)

    Rauscher, H.M.; Alban, D.H.; Johnson, D.W.

    1992-01-01

    The general objective of this project is the development of a hypertext-based scientific assessment on the subject of mitigating climate change by sequestering carbon in soils. Specifically, the authors want to (1) translate the scientific knowledge base on soil carbon cycling into a form meaningful for policy makers by using the theory of issue-based hypertext for problem solving using the argumentative approach developed by the late Horst Rittel, professor of planning and design at the University of California, Berkeley; (2) provide an organized and evaluated scientific knowledge base on soil carbon dynamics for research scientists to aid in the rapid and economical review and understanding of the subfield of science; and (3) test this new hybrid hypertext and AI methodology for use as a tool for program managers to help them evaluate a research domain to find knowledge gaps, to prioritize these knowledge gaps, to channel available research funding to these projects aimed at filling the most promising knowledge gaps in order to have the greatest possible impact on the entire knowledge base of the field, and to help explicitly measure scientific progress in terms that funding sources can understand. The authors began this project in fall 1991 and expect to complete it by fall 1993

  2. Metabolic profiling of residents in the vicinity of a petrochemical complex

    International Nuclear Information System (INIS)

    Yuan, Tzu-Hsuen; Chung, Ming-Kei; Lin, Ching-Yu; Chen, Shu-Ting; Wu, Kuen-Yuh; Chan, Chang-Chuan

    2016-01-01

    No previous studies have simultaneously measured the biomarkers of environmental exposure and metabolome perturbation in residents affected by industrial pollutants. This study aimed to investigate the metabolic effects of environmental pollutants such as vanadium and polycyclic aromatic hydrocarbons (PAHs) on residents in the vicinity of a petrochemical complex. The study subjects were 160 residents, including 80 high-exposure subjects exposed to high levels of vanadium and PAHs and 80 age- and gender-matched low-exposure subjects living within a 40-km radius of a petrochemical complex. The exposure biomarkers vanadium and 1-hydroxypyrene and four oxidative/nitrosative stress biomarkers were measured in these subjects. Plasma samples from the study subjects were also analyzed using "1H NMR spectroscopy for metabolic profiling. The results showed that the urinary levels of vanadium and 1-hydroxypyrene in the high-exposure subjects were 40- and 20-fold higher, respectively, than those in the low-exposure subjects. Higher urinary levels of stress biomarkers, including 8-OHdG, HNE-MA, 8-isoPF2α, and 8-NO_2Gua, were also observed among the high-exposure subjects compared with the low-exposure subjects. Partial least squares discriminant analysis of the plasma metabolome demonstrated a clear separation between the high- and low-exposure subjects; the intensities of amino acids and carbohydrate metabolites were lower in the high-exposure subjects compared with the low-exposure subjects. The exposure to vanadium and PAHs may cause a reduction in the levels of amino acids and carbohydrates by elevating PPAR and insulin signaling, as well as oxidative/nitrosative stress. - Highlights: • Metabolic effects when exposure to pollutants near a petrochemical complex • V and PAHs exposure associated with elevated oxidative/nitrosative stress responses • V and PAHs exposure related to reduced amino acid and carbohydrate levels • V and PAHs affect metabolic profiling by

  3. Metabolic profiling of residents in the vicinity of a petrochemical complex

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Tzu-Hsuen; Chung, Ming-Kei [Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan (China); Lin, Ching-Yu [Institute of Environmental Health, College of Public Health, National Taiwan University, Taipei, Taiwan (China); Chen, Shu-Ting; Wu, Kuen-Yuh [Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan (China); Chan, Chang-Chuan, E-mail: ccchan@ntu.edu.tw [Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan (China)

    2016-04-01

    No previous studies have simultaneously measured the biomarkers of environmental exposure and metabolome perturbation in residents affected by industrial pollutants. This study aimed to investigate the metabolic effects of environmental pollutants such as vanadium and polycyclic aromatic hydrocarbons (PAHs) on residents in the vicinity of a petrochemical complex. The study subjects were 160 residents, including 80 high-exposure subjects exposed to high levels of vanadium and PAHs and 80 age- and gender-matched low-exposure subjects living within a 40-km radius of a petrochemical complex. The exposure biomarkers vanadium and 1-hydroxypyrene and four oxidative/nitrosative stress biomarkers were measured in these subjects. Plasma samples from the study subjects were also analyzed using {sup 1}H NMR spectroscopy for metabolic profiling. The results showed that the urinary levels of vanadium and 1-hydroxypyrene in the high-exposure subjects were 40- and 20-fold higher, respectively, than those in the low-exposure subjects. Higher urinary levels of stress biomarkers, including 8-OHdG, HNE-MA, 8-isoPF2α, and 8-NO{sub 2}Gua, were also observed among the high-exposure subjects compared with the low-exposure subjects. Partial least squares discriminant analysis of the plasma metabolome demonstrated a clear separation between the high- and low-exposure subjects; the intensities of amino acids and carbohydrate metabolites were lower in the high-exposure subjects compared with the low-exposure subjects. The exposure to vanadium and PAHs may cause a reduction in the levels of amino acids and carbohydrates by elevating PPAR and insulin signaling, as well as oxidative/nitrosative stress. - Highlights: • Metabolic effects when exposure to pollutants near a petrochemical complex • V and PAHs exposure associated with elevated oxidative/nitrosative stress responses • V and PAHs exposure related to reduced amino acid and carbohydrate levels • V and PAHs affect metabolic

  4. Serum Protein Profile Study of Clinical Samples Using High Performance Liquid Chromatography-Laser Induced Fluorescence

    DEFF Research Database (Denmark)

    Karemore, Gopal Raghunath; Ukendt, Sujatha; Rai, Lavanya

    2009-01-01

    The serum protein profiles of normal subjects, patients diagnosed with cervical cancer, and oral cancer were recorded using High Performance Liquid Chromatography combined with Laser Induced Fluorescence detection (HPLC-LIF). Serum protein profiles of the above three classes were tested for estab...

  5. The impact of genetics and hormonal contraceptives on the steroid profile in female athletes

    Directory of Open Access Journals (Sweden)

    Jenny Erkander Mullen

    2014-04-01

    Full Text Available The steroid module of the Athlete Biological Passport (ABP, the newest innovation in doping testing, is currently being finalized for implementation. Several factors, other than doping, can affect the longitudinal steroid profile. In this study we investigated the effect of hormonal contraceptives as well as the effect of three polymorphisms on female steroid profiles in relation to doping controls.The study population consisted of 79 female elite athletes between the ages of 18 to 45. Hormonal contraceptives were used by 32 % of the subjects. A full urinary steroid profile was obtained using World Anti-Doping Agency accredited methods. In addition all subjects were genotyped for copy number variation of UGT2B17 and SNPs in UGT2B7 and CYP17.Subjects using hormonal contraceptives excreted 40 % less epitestosterone as compared to non-users (p = 0.005 but showed no difference in testosterone excretion. When removing individuals homozygous for the deletion in UGT2B17, the testosterone to epitestosterone (T/E ratio was 29 % higher in the hormonal contraceptives group (p = 0.016. In agreement with previous findings in men, copy number variation of UGT2B17 had significant effect on female urinary testosterone excretion and therefore also the T/E ratio. Subjects homozygous for the T allele of CYP17 showed a lower urinary epitestosterone concentration than the other CYP17 genotypes. It is of great importance that the athlete’s steroidal passport can compensate for all possible normal variability in steroid profiles from women. Therefore, considering the large impact of hormonal contraceptives on female steroid profiles, we suggest that the use of hormonal contraceptives should be a mandatory question on the doping control form.

  6. Urine metabonomic profiling of a female adolescent with PIT-1 mutation before and during growth hormone therapy: insights into the metabolic effects of growth hormone.

    Science.gov (United States)

    Abd Rahman, Shaffinaz; Schirra, Horst Joachim; Lichanska, Agnieszka M; Huynh, Tony; Leong, Gary M

    2013-01-01

    Growth hormone (GH) is a protein hormone with important roles in growth and metabolism. The objective of this study was to investigate the metabolism of a human subject with severe GH deficiency (GHD) due to a PIT-1 gene mutation and the metabolic effects of GH therapy using Nuclear Magnetic Resonance (NMR)-based metabonomics. NMR-based metabonomics is a platform that allows the metabolic profile of biological fluids such as urine to be recorded, and any alterations in the profile modulated by GH can potentially be detected. Urine samples were collected from a female subject with severe GHD before, during and after GH therapy, and from healthy age- and sex-matched controls and analysed with NMR-based metabonomics. The samples were collected at a hospital and the study was performed at a research facility. We studied a 17 year old female adolescent with severe GHD secondary to PIT-1 gene mutation who had reached final adult height and who had ceased GH therapy for over 3 years. The subject was subsequently followed for 5 years with and without GH therapy. Twelve healthy age-matched female subjects acted as control subjects. The GH-deficient subject re-commenced GH therapy at a dose of 1 mg/day to normalise serum IGF-1 levels. Urine metabolic profiles were recorded using NMR spectroscopy and analysed with multivariate statistics to distinguish the profiles at different time points and identify significant metabolites affected by GH therapy. NMR-based metabonomics revealed that the metabolic profile of the GH-deficient subject altered with GH therapy and that her profile was different from healthy controls before, and during withdrawal of GH therapy. This study illustrates the potential use of NMR-based metabonomics for monitoring the effects of GH therapy on metabolism by profiling the urine of GH-deficient subjects. Further controlled studies in larger numbers of GH-deficient subjects are required to determine the clinical benefits of NMR-based metabonomics in

  7. Designing scientific applications on GPUs

    CERN Document Server

    Couturier, Raphael

    2013-01-01

    Many of today's complex scientific applications now require a vast amount of computational power. General purpose graphics processing units (GPGPUs) enable researchers in a variety of fields to benefit from the computational power of all the cores available inside graphics cards.Understand the Benefits of Using GPUs for Many Scientific ApplicationsDesigning Scientific Applications on GPUs shows you how to use GPUs for applications in diverse scientific fields, from physics and mathematics to computer science. The book explains the methods necessary for designing or porting your scientific appl

  8. The scientific production of Nutrition published by the Scientific Electronic Library under the gaze of the evaluation of the Coordination for the Development of Higher Education Personnel

    Directory of Open Access Journals (Sweden)

    Francisco de Assis Guedes de VASCONCELOS

    Full Text Available ABSTRACT Objective: Perform analysis of the scientific production of Nutrition published by the Scientific Electronic Library under the gaze of the evaluation of Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. Methods: Systematic search was performed in the 286 current title journals, using the "article search" path, the "subject index" window and the "Nutrition" indexer. The articles and periodicals selected were analyzed in order to answer the following questions: Which journals from Scientific Electronic Library publish articles on Nutrition? Do these journals have an impact factor as measured by the Journal Citation Reports? Which are? What is the classification of these journals by the areas of evaluation of Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, specifically by the area of Nutrition? Results: We analyzed 779 articles published in 85 journals. The majority of articles (n=698; 89.6% were related to the area of Health Sciences. The five journals with higher volumes of articles were: Brazilian Journal of Nutrition, Reports in Public Health, Public Health Journal, Science & Public Health and Journal of Pediatrics. Most (62.4% does not have Journal Citation Reports. The Nutrition area not rated any journal in strata A1 and A2, classifying them from B1 to B4. For eight areas analyzed their specific journals were induced to the upper strata of Qualis (A1, A2 and B1. Conclusion: The analyzed journals are the main vehicles of circulation of scientific paradigms of national scientific communities. Considering the correlation of forces between the vehicles of circulation of scientific knowledge in the international context, stimuli for valorization and qualification of these journals are essential.

  9. Jenkins-CI, an Open-Source Continuous Integration System, as a Scientific Data and Image-Processing Platform

    Science.gov (United States)

    Moutsatsos, Ioannis K.; Hossain, Imtiaz; Agarinis, Claudia; Harbinski, Fred; Abraham, Yann; Dobler, Luc; Zhang, Xian; Wilson, Christopher J.; Jenkins, Jeremy L.; Holway, Nicholas; Tallarico, John; Parker, Christian N.

    2016-01-01

    High-throughput screening generates large volumes of heterogeneous data that require a diverse set of computational tools for management, processing, and analysis. Building integrated, scalable, and robust computational workflows for such applications is challenging but highly valuable. Scientific data integration and pipelining facilitate standardized data processing, collaboration, and reuse of best practices. We describe how Jenkins-CI, an “off-the-shelf,” open-source, continuous integration system, is used to build pipelines for processing images and associated data from high-content screening (HCS). Jenkins-CI provides numerous plugins for standard compute tasks, and its design allows the quick integration of external scientific applications. Using Jenkins-CI, we integrated CellProfiler, an open-source image-processing platform, with various HCS utilities and a high-performance Linux cluster. The platform is web-accessible, facilitates access and sharing of high-performance compute resources, and automates previously cumbersome data and image-processing tasks. Imaging pipelines developed using the desktop CellProfiler client can be managed and shared through a centralized Jenkins-CI repository. Pipelines and managed data are annotated to facilitate collaboration and reuse. Limitations with Jenkins-CI (primarily around the user interface) were addressed through the selection of helper plugins from the Jenkins-CI community. PMID:27899692

  10. Jenkins-CI, an Open-Source Continuous Integration System, as a Scientific Data and Image-Processing Platform.

    Science.gov (United States)

    Moutsatsos, Ioannis K; Hossain, Imtiaz; Agarinis, Claudia; Harbinski, Fred; Abraham, Yann; Dobler, Luc; Zhang, Xian; Wilson, Christopher J; Jenkins, Jeremy L; Holway, Nicholas; Tallarico, John; Parker, Christian N

    2017-03-01

    High-throughput screening generates large volumes of heterogeneous data that require a diverse set of computational tools for management, processing, and analysis. Building integrated, scalable, and robust computational workflows for such applications is challenging but highly valuable. Scientific data integration and pipelining facilitate standardized data processing, collaboration, and reuse of best practices. We describe how Jenkins-CI, an "off-the-shelf," open-source, continuous integration system, is used to build pipelines for processing images and associated data from high-content screening (HCS). Jenkins-CI provides numerous plugins for standard compute tasks, and its design allows the quick integration of external scientific applications. Using Jenkins-CI, we integrated CellProfiler, an open-source image-processing platform, with various HCS utilities and a high-performance Linux cluster. The platform is web-accessible, facilitates access and sharing of high-performance compute resources, and automates previously cumbersome data and image-processing tasks. Imaging pipelines developed using the desktop CellProfiler client can be managed and shared through a centralized Jenkins-CI repository. Pipelines and managed data are annotated to facilitate collaboration and reuse. Limitations with Jenkins-CI (primarily around the user interface) were addressed through the selection of helper plugins from the Jenkins-CI community.

  11. In question: the scientific value of preclinical safety pharmacology and toxicology studies with cell-based therapies

    Directory of Open Access Journals (Sweden)

    Christiane Broichhausen

    2014-01-01

    Full Text Available A new cell-based medicinal product containing human regulatory macrophages, known as Mreg_UKR, has been developed and conforms to expectations of a therapeutic drug. Here, Mreg_UKR was subjected to pharmacokinetic, safety pharmacology, and toxicological testing, which identified no adverse reactions. These results would normally be interpreted as evidence of the probable clinical safety of Mreg_UKR; however, we contend that, owing to their uncertain biological relevance, our data do not fully support this conclusion. This leads us to question whether there is adequate scientific justification for preclinical safety testing of similar novel cell-based medicinal products using animal models. In earlier work, two patients were treated with regulatory macrophages prior to kidney transplantation. In our opinion, the absence of acute or chronic adverse effects in these cases is the most convincing available evidence of the likely safety of Mreg_UKR in future recipients. On this basis, we consider that safety information from previous clinical investigations of related cell products should carry greater weight than preclinical data when evaluating the safety profile of novel cell-based medicinal products. By extension, we argue that omitting extensive preclinical safety studies before conducting small-scale exploratory clinical investigations of novel cell-based medicinal products data may be justifiable in some instances.

  12. Evil as a Subject of Sociological Cognition: Methodological Reflections

    Directory of Open Access Journals (Sweden)

    Temyr Khagurov

    2017-07-01

    Full Text Available In this article, the question of opportunities and boundaries of scientific research of the evil is considered. It is emphasized that the notion “evil” is widely used in politics and journalism for the description of the most vital issues of the present, for instance, international terrorism. It induces social scientists to the methodological reflection of scientific and philosophical attempts of conceptualization, description and analysis of a complex of the phenomena and processes determined by the term “evil.” A brief review of such attempts in science and philosophy of the 20th century is carried out. Despite the marginal status of the notions of Good and Evil in modern scientific discourse, the main scientific and philosophical concepts of human and society recognized in the 20th century admit the possibility of using these notions. Despite the fact that the idea of Evil is difficult to interpret as a concept term, which is the major obstacle to a scientific application of this, it is inappropriate to name it as unidentified. Such interpretation seems relevant to both social phenomena and anthropological ones. It is noted that the essential postulates of the modern scientific perception of “The Evil” analysis in sociology have been obtained in the writings of Karl Marx, Émile Durkheim, Karl Popper, Sigmund Freud and Friedrich Nietzsche. Those were Marx and Nietzsche who stated the polar vision of the phenomenology of Evil on the socio-philosophical level. Herewith, the survey of the conceptualizations and approaches to this problem is not limited with the abovementioned scientists, but involves the ideas and researches of a quite wide range of sociologists, philosophers and psychologists of the 20th century. Thus, the contents of the article, i.e. the overview of concepts and ideas, cannot be considered as the extensive one as the theme and the reference sources analyzed are boundless. This issue is to be regarded just as an

  13. Progress and perspectives of the Brazilian scientific production in international journals in the field of motor behavior

    Directory of Open Access Journals (Sweden)

    Ana Paula Kogake Claudio

    2009-09-01

    Full Text Available In view of the fact that one of the key indicators of scientific production is the number of papers published in international journals, and of the apparent growing interest in the area of motor behavior, we conducted a survey of articles published by Brazilian researchers in this area over the last 10 years (1999-2008 in international journals rated “Qualis International-A” and “Qualis International-B” by CAPES. This quantification was performed to provide a qualified viewpoint regarding the profile of Brazilian scientific production of international repercussion in the area of motor behavior. Articles were identified using the Google Scholar, Pubmed, Science Direct, and Scopus search systems, with the search being restricted to characteristic terms involving motor behavior and to researchers associated with Brazilian universities. The results showed an increase in production over the last 5 years of the period studied, with the peak in 2006. In addition, Brazilian scientific production was concentrated in four public universities. These results suggest that in order to keep growing, the new groups should work in collaboration with productive laboratories, decentralizing the scientific production.

  14. The analysis of scientific communications and students’ character development through guided inquiry learning

    Science.gov (United States)

    Sarwi, S.; Fauziah, N.; Astuti, B.

    2018-03-01

    This research is setting by the condition of students who have difficulty in ideas delivery, written scientific communication, and still need the development of student character. The objectives of the research are to determine the improvement of concept understanding, to analyze scientific communication skills and to develop the character of the students through guided inquiry learning. The design in this research is quasi experimental control group preposttest, with research subject of two group of grade X Senior High School in Semarang. One group of controller uses non tutorial and treatment group using tutorial in guided inquiry. Based on result of gain test analysis, obtained = 0.71 for treatment and control group = 0.60. The t-test result of mean mastery of concept of quantity and unit using t-test of right side is t count = 2.37 (p=0.003) while t table = 1.67 (α = 5%), which means that the results of the study differed significantly. The results of the students' scientific communication skills analysis showed that the experimental group was higher than the control, with an average of 69% and 63% scientific communication skills. The character values are effective developed through guided inquiry learning. The conclusion of the study is guided inquiry learning tutorial better than guided inquiry non tutorial learning in aspect understanding concept, scientific communication skills; but the character development result is almost the same.

  15. List of scientific publications from the Karlsruhe Nuclear Research Centre of the year 1977

    International Nuclear Information System (INIS)

    1978-03-01

    The scientific and technical-scientific publications from the Karlsruhe Nuclear Research Centre comprise books, original papers in scientific or technical journals, diploma, doctoral and habilitation theses, as well as papers held at scientific conferences, patents, KfK reports, and external reports (KfK = Kernforschungszentrum Karlsruhe). The present report, KfK 2625, contains the titles of the 1977 publications, scientific papers being listed only after the manusscript has been filed in the Central Library of the research centre. As for patents, the titles given refer to either first issues of a patent, or to patents laid open for inspection. Progress reports are listed according to subjects involved. The whole list of publications is ordered according to the names of institutes and of projects, the latter group covering the titles of published project reports and of publications written by individual cooperators of a given project, as well as publications printed by the Karlsruhe Nuclear Research Centre, written by cooperators of the following projects: 'Process control with data processing plants', (PDV), and 'Computer-assisted development' (CAD). These projects are carried out together with other firms and instutes. Yet another group of publications covered are those of the Federal Institute for Food Research, and of guest scientists working in the Centre. (orig./HK) [de

  16. Promoting the 21st century scientific literacy skills through innovative chemistry instruction

    Science.gov (United States)

    Rahayu, Sri

    2017-12-01

    Students need to be equipped with the 21st century skills/capabilities to ensure their competitiveness in the knowledge era. So, it is imperative that education at school should be changed in order to fulfill the need. However, there is not any specified approach on how to educate young students for the 21st century capabilities. Regardless the impediment for ts exist, we need to construct an innovative instruction that can develop the students' 21st century skills by incorporating the skills needed, based on contemporary theory of learning, necessary context of learning and appropriate assessment in a chemistry subject matter. This paper discuss the feasible skills to be promoted through chemistry course. Those skills/capabilities are scientific literacy, higher order thinking, communicationand collaboration and curiosity. The promoted are called the 21st century scientific literacy skills in which it emphasis on scientific literacy and embedded the other 21st century skills into the innovative chemistry instruction. The elements involve in the instruction such as inquiry and constructivist approach, nature of science, contemporary/socioscientific issues, critical thinking (higher order thinking).

  17. Educational radio to encourage the scientific vocations: The ‘Laboratory Mice’ project

    Directory of Open Access Journals (Sweden)

    Daniel Martín-Pena

    2018-05-01

    Full Text Available The aim of the scientific dissemination project ‘Laboratory mice’ is to approach to science, through education radio, to elementary students in Extremadura (Spain. This innovative initiative has allowed to reach nearly half a thousand students between 9 and 13 years old. An informative experience with a novel work methodology consisting in the elaboration of radio spaces where the leads have been the students themselves, who have previously received practical workshops carried out by researchers from the University of Extremadura and who explain the scientific issues of daily life. In this article is hoped to explain all the stages of Project and investigation instruments that have been used to know the student experiences and how have actions influenced in the public perception of science between the school community at an early ages. The main conclusion has been the improvement of the perception by the student of the work done by the scientists and the increase of the interest in the subjects connected to the scientific scope in favor of the STEM vocations.

  18. ERINDA Scientific Results: Transnational Access Activities and Scientific Visits

    CERN Document Server

    Hambsch, Franz-Josef

    2014-01-01

    This paper gives an overview of the Transnational Access Activities and Scientific visits within the FP7 project ERINDA (European Research Infrastructures for Nuclear Data). It highlights the fact that nearly 3200 data - taking hours for external users were made available in the partner installations and 104 man weeks for scientific visits to par tner institutes. This is much more than the 2500 beam hours and 80 weeks promised in the Description of Work of the project.

  19. Professional Group Development Trainers’ Personality Characteristics and Affective Profiles

    Directory of Open Access Journals (Sweden)

    Max eRapp Ricciardi

    2014-10-01

    Full Text Available Background: The Development of Groups and Leaders (UGL, provided by the Swedish National Defence College and mentored by UGL-trainers, is one of the most popular management programs among civilians in Sweden. However, there is a lack of scientific evidence regarding the training. We used the affective profile model (i.e., the combination of positive, PA, and negative affect, NA to mapp important markers of empowerment, self-awareness, adaptive coping skills, and maturity among the UGL-trainers. The aims were: (1 to compare profiles between UGL-trainers and managers/supervisors and (2 to investigate differences in personal characteristics.Method: UGL-trainers (N = 153 and the comparison group (104 Swedish Chiefs of Police completed an online survey on optimism, self-esteem, locus of control, and affect. The four profiles are: self-fulfilling (high PA, low NA, high affective (high PA, high NA, low affective (high PA, low NA, and self-destructive (low PA, high NA,Results: The self-fulfilling profile was more common among UGL-trainers (25.70% than among Chiefs of Police (19.20%. UGL-trainers, compared to Chiefs of Police, were more likely to express a self-fulling than a low affective profile (OR=2.22, p < .05 and a high affective than a low affective profile (OR=1.43, p <.001. UGL-trainers with a self-fulfilling profile, compared to those with a self-destructive profile, scored higher in optimism, higher in self-esteem, and lower in external locus of control. Conclusions: The probability of self-fulfilment rather than low affectivity was higher among UGL-trainers. Self-fulfilment was associated to markers of self-awareness and adaptive coping skills. However, the most common profile was the low affective, which is associated to low performance during stress, low degree of personal development, low degree of purpose in life, and low resilience. Hence, it might be important for UGL-trainers to have a continuos training in awareness after

  20. Scientific institution’s ways of communicating with the environment

    Directory of Open Access Journals (Sweden)

    Joanna Pruchnicka

    2014-06-01

    Full Text Available The Internet has given its users ways for fast and inexpensive publication of information, dissemination of their creativity, experiences and thoughts.Blogs have become one of the forms particularly popular over the recent years.Impact of blogs on the audience has turned out to be so significant that they quickly have begun to be used as a marketing tool, both in the area of public relations as well as advertising. By definition, blog imposes a significant simplification on the message conveyed, both in terms of content and language, making them more legible, comprehensible and interesting for each recipient.This makes this form of communication extremely attractive for science, especially in the context of its commercialization and dissemination of information on the scientific and research achievements. For science, scientific and research institutions and scientists a certain dualism arises in the approach to using blogs as a means of communicating with the environment.On one hand, blogs provide a quick, simple transmission of information and knowledge, on the other hand, most people feel that scientific blogs lack credibility and seriousness usually associated with messages coming from the world of science, research and experiments. For many years, blog have been extremely popular, even the required form of communication used by the American and Western scientists.There is a growing awareness of the merits of blogging on the subjects of science in Poland. However, in the opinion of the respondents of the research presented in the article, the dominant tools for the dissemination and promotion of science are scientific conferences and publications, namely those which by their very nature limit the range and spread of information.

  1. Antibiotic resistant profile of Streptococcus pneumoniae from the ...

    African Journals Online (AJOL)

    The isolates were subjected to antimicrobial susceptibility testing using the disc diffusion method. Results: S. pneumoniae was isolated from 37(42.04%) of the 88 samples. Isolates showed the highest resistance of 12 (32.43%) to erythromycin and lowest resistance of 4(10.81%) to ciprofloxacin. The resistance profiles for ...

  2. Newsworthiness vs scientific impact: are the most highly cited urology papers the most widely disseminated in the media?

    Science.gov (United States)

    O'Connor, Eabhann M; Nason, Gregory J; O'Kelly, Fardod; Manecksha, Rustom P; Loeb, Stacy

    2017-09-01

    To assess whether a correlation exists between newsworthiness (Altmetric score) and scientific impact markers, such as citation analysis, impact factors, and levels of evidence. The top five most cited articles for the year 2014 and 2015 from the top 10 ranking urology journals (Scientific Impact Group) were identified. The top 50 articles each in 2014 and 2015 were identified from Altmetric support based on media activity (Media Impact Group). We determined the number of citations that these articles received in the scientific literature, and calculated correlations between citations with Altmetric scores. In the Scientific Impact Group, the mean number of citations per article was 37.6, and the most highly cited articles were oncology guidelines. The mean Altmetric score in these articles was 14.8. There was a weak positive correlation between citations and Altmetric score (r s = 0.35, 95% confidence interval 0.16-0.52, P scientifically rigorous, or that this audience places greater value on different subjects than the scientific community. © 2017 The Authors BJU International © 2017 BJU International Published by John Wiley & Sons Ltd.

  3. Primary pre-service teachers' skills in planning a guided scientific inquiry

    Science.gov (United States)

    García-Carmona, Antonio; Criado, Ana M.; Cruz-Guzmán, Marta

    2017-10-01

    A study is presented of the skills that primary pre-service teachers (PPTs) have in completing the planning of a scientific inquiry on the basis of a guiding script. The sample comprised 66 PPTs who constituted a group-class of the subject Science Teaching, taught in the second year of an undergraduate degree in primary education at a Spanish university. The data was acquired from the responses of the PPTs (working in teams) to open-ended questions posed to them in the script concerning the various tasks involved in a scientific inquiry (formulation of hypotheses, design of the experiment, data collection, interpretation of results, drawing conclusions). Data were analyzed within the framework of a descriptive-interpretive qualitative research study with a combination of inter- and intra-rater methods, and the use of low-inference descriptors. The results showed that the PPTs have major shortcomings in planning the complete development of a guided scientific inquiry. The discussion of the results includes a number of implications for rethinking the Science Teaching course so that PPTs can attain a basic level of training in inquiry-based science education.

  4. Forefoot deformity, pain, and mobility in rheumatoid and nonarthritic subjects.

    Science.gov (United States)

    O'Connell, P G; Lohmann Siegel, K; Kepple, T M; Stanhope, S J; Gerber, L H

    1998-09-01

    To evaluate how painful metatarsal arthritis affects foot and ankle mechanics and mobility. We studied 16 symptomatic forefeet in 10 patients with rheumatoid arthritis (RA) and compared them with 14 asymptomatic forefeet in 7 nonarthritic subjects. RA limbs with significant disease at other locations were excluded. We measured pain and deformity of the foot using a visual analog scale and a modified articular index. A video based 3 dimensional gait analysis system and force platform were used to collect data on subjects walking barefoot at a self-selected pace according to an established protocol. Mobility level was quantified using the Sickness Impact Profile (SIP) ambulation subscale. We observed considerable pain and deformity of the forefeet of RA subjects. During gait, motion and force measures revealed that RA subjects significantly (p SIP scores revealed that these changes in gait resulted in moderate disability in RA subjects (p=0.05). Impairments of the forefoot due to RA include pain and deformity, which produce characteristic stance phase abnormalities in foot function, a slow walking speed, and moderate disability.

  5. Learning by doing? Prospective elementary teachers' developing understandings of scientific inquiry and science teaching and learning

    Science.gov (United States)

    Haefner, Leigh Ann; Zembal-Saul, Carla

    This study examined prospective elementary teachers' learning about scientific inquiry in the context of an innovative life science course. Research questions included: (1) What do prospective elementary teachers learn about scientific inquiry within the context of the course? and (2) In what ways do their experiences engaging in science investigations and teaching inquiry-oriented science influence prospective elementary teachers' understanding of science and science learning and teaching? Eleven prospective elementary teachers participated in this qualitative, multi-participant case study. Constant comparative analysis strategies attempted to build abstractions and explanations across participants around the constructs of the study. Findings suggest that engaging in scientific inquiry supported the development more appropriate understandings of science and scientific inquiry, and that prospective teachers became more accepting of approaches to teaching science that encourage children's questions about science phenomena. Implications include careful consideration of learning experiences crafted for prospective elementary teachers to support the development of robust subject matter knowledge.

  6. Monte Carlo study of thermal flux profiles and body correction factors for body protein measurements of obese subjects

    International Nuclear Information System (INIS)

    McGregor, B.J.; Allen, B.J.

    1991-01-01

    In previous calculations for total body nitrogen measurements of children, the anterior/posterior thermal neutron flux profile with depth was found to be fairly flat after an initial rise. However, for obese adults significant variations are found in the flux profile with the central flux value being as low as 20% of the peak value. The significance of these flux variations is examined. Correction factors are calculated for the varying attenuation of the nitrogen and hydrogen photons by a range of obese bodies. The calculations included the effect of the thermal flux profile as well as that of an outer layer of low nitrogen content adipose tissue. The bodies are assumed to have a homogeneous hydrogen content. A study of four obese body models with varying sex and fat content shows that the correction factors do not vary much between males and females. This is surprising since the female models are assumed to have a surface fat layer twice as thick as for the male models. The correction factors are found to be only slightly sensitive to the thermal flux variations with depth. 5 refs., 1 tab., 4 figs

  7. The Uncertain of Scientific Process

    Directory of Open Access Journals (Sweden)

    Jovina dÁvila Bordoni

    2016-10-01

    Full Text Available The study assesses the existence of certainty in the scientific process, it seeks the truth, however, faced with the unknown, causes uncertainties and doubts. We used the bibliographical research, in which it systematized the scientific literature on epistemology and knowledge related to the scientific process and the uncertainties that surround him. The scientific process, though continuously seeks the truth, will not attain perfection, because the researcher deals with the unknown. The science seeks constantly new knowledge and progress with the criticism of the mistakes, seeks the truth, however these are provisional. It is concluded that all scientific knowledge is uncertain.

  8. Scientific collaboratories in higher education

    DEFF Research Database (Denmark)

    Sonnenwald, Diane H.; Li, Bin

    2003-01-01

    Scientific collaboratories hold the promise of providing students access to specialized scientific instruments, data and experts, enabling learning opportunities perhaps otherwise not available. However, evaluation of scientific collaboratories in higher education has lagged behind...

  9. Microbiome Profiles in Periodontitis in Relation to Host and Disease Characteristics

    Science.gov (United States)

    Hong, Bo-Young; Furtado Araujo, Michel V.; Strausbaugh, Linda D.; Terzi, Evimaria; Ioannidou, Effie; Diaz, Patricia I.

    2015-01-01

    Periodontitis is an inflammatory condition that affects the supporting tissues surrounding teeth. The occurrence of periodontitis is associated with shifts in the structure of the communities that inhabit the gingival sulcus. Although great inter-subject variability in the subgingival microbiome has been observed in subjects with periodontitis, it is unclear whether distinct community types exist and if differences in microbial signatures correlate with host characteristics or with the variable clinical presentations of periodontitis. Therefore, in this study we explored the existence of different community types in periodontitis and their relationship with host demographic, medical and disease-related clinical characteristics. Clustering analyses of microbial abundance profiles suggested two types of communities (A and B) existed in the 34 subjects with periodontitis evaluated. Type B communities harbored greater proportions of certain periodontitis-associated taxa, including species historically associated with the disease, such as Porphyromonas gingivalis, Tannerella forsythia and Treponema denticola, and taxa recently linked to periodontitis. In contrast, subjects with type A communities had increased proportions of different periodontitis-associated species, and were also enriched for health-associated species and core taxa (those equally prevalent in health and periodontitis). Periodontitis subgingival clusters were not associated with demographic, medical or disease-specific clinical parameters other than periodontitis extent (proportion of sites affected), which positively correlated with the total proportion of cluster B signature taxa. In conclusion, two types of microbial communities were detected in subjects with periodontitis. Host demographics and underlying medical conditions did not correlate with these profiles, which instead appeared to be related to periodontitis extent, with type B communities present in more widespread disease cases. The two

  10. Materials of 46. Scientific Assembly of Polish Chemical Society and Association of Engineers and Technicians of Chemical. Volume 1,2,3

    International Nuclear Information System (INIS)

    2003-01-01

    Scientific assemblies of Polish Chemical Society are the most important chemical meetings organised annually in Poland. Basic as well as application studies in all chemical branches have been extensively presented. The next subjects were proposed as scientific sessions and symposia topics: organic chemistry, inorganic chemistry, physical chemistry, analytical chemistry, technology and chemical engineering, polymer chemistry, solid state chemistry, catalysis, biological chemistry, chemistry and technology of coal, environmental protection, didactics of chemistry, history of chemistry, young scientist forum as well as the reports of results of works sponsored by Committee of Scientific Research

  11. Implicit normativity in scientific advice

    DEFF Research Database (Denmark)

    Folker, Anna Paldam; Andersen, Hanne; Sandøe, Peter

    2008-01-01

    This paper focuses on implicit normative considerations underlying scientific advice-those normative questions, decisions, or issues that scientific advisers and the general public are not fully aware of but that nevertheless have implications for the character of the advice given. Using...... nutritional science as an example, we identify three such implicit normative issues. The first concerns the aim of scientific advice: whether it is about avoiding harm or promoting good. The second concerns the intended beneficiaries of the advice: whether advice should be framed to benefit the society...... as a whole or with special concern for the most vulnerable members of the population. The third consideration involves scientific advisers' attempts to balance the strengths of the scientific evidence with the expected consequences of scientific advice. We hope to promote more explicit discussion...

  12. Don’t be too strict with yourself! Rigid negative self-representation in healthy subjects mimics the neurocognitive profile of depression for autobiographical memory.

    Directory of Open Access Journals (Sweden)

    Marco eSperduti

    2013-05-01

    Full Text Available Autobiographical memory (AM comprises representation of specific (episodic and generic personal information (semantic. Depression is characterized by a shift from episodic to semantic AM retrieval (overgeneralization. Theoretical models have proposed that this effect could be linked to reduced executive resources. Moreover, overgeneral memories, accompanied by a negativity bias in depression, lead to a pervasive negative self-representation. Even in non clinical populations executive functions and AM specificity are closely linked, and overgeneral memories could result in depressive emotional responses. We made the hypothesis that healthy subjects showing a rigid negative self-image would mimic the neurocognitive profile of patients. We measured executive functions and the self-image in young healthy subjects, and recorded their brain activity, by means of fMRI, while they retrieved episodic AMs. We report that a more rigid negative self-image corresponds to lower executive functions and less vivid specific memories. Moreover, higher negative self-image is accompanied by attenuated activity in the left ventrolateral prefrontal and in the anterior cingulate cortex, that have been repeatedly shown to exhibit altered functionality in depression. Activity in these regions, on the contrary, positively correlates with executive and memories performances, in agreement with their role in executive functions and AM retrieval. We claim that rigid negative self-image could represent a marker or a vulnerability trait of depression that is linked to reduced executive functions efficiency and to episodic AM decline. Our results are encouraging for psychotherapeutic approaches promoting cognitive flexibility in depression and other psychiatric disorders.

  13. Assessing Quality of Life using the Oral Health Impact Profile (OHIP-14) in Subjects with and without Orthodontic Treatment need in Chennai, Tamil Nadu, India.

    Science.gov (United States)

    Mary, A Vinita; Mahendra, Jaideep; John, Joseph; Moses, Joyson; Ebenezar, A V Rajesh; Kesavan, R

    2017-08-01

    Dental ailments like malocclusion affect not only the functional ability and aesthetic appearance of the person but also the psychological aspect of the individual. The aim of the present study was to the find relationship between quality of life and dental malocclusion among school going adolescents in Tamil Nadu, India. A cross-sectional study was conducted among 342 subjects of age range 14-19 years. Oral health status was assessed using WHO basic oral health survey (2013), orthodontic treatment needs according to Index of Orthodontic Treatment Needs (IOTN) and oral health quality of life using Oral Health Impact Profile-14 (OHIP-14). A total of 342 subjects were interviewed and examined. The mean DMFT score was 1.86±2.77. A 203 (59.4%) did not require any orthodontic treatment while 139 (40.6%) had orthodontic treatment need ranging from mild to very severe. It was seen that malocclusion affected some aspects of OHIP-14 significantly namely functional limitation, psychological discomfort and psychological disability. The comparison of OHIP-14 scores between treatment needed and treatment not needed was highly significant (p<0.001). Hence, it is stated that there is an urgent need to educate the school children and in turn their parents regarding the malocclusion for its treatment to prevent any effect on quality of life of the young adults.

  14. General characteristics and types of subjective duties in corporate legal relations

    OpenAIRE

    Надьон, Вікторія Валентинівна

    2017-01-01

    The processes of reforming social relations in the conditions of integration ofUkraine's economic system into the European community call for the improvement of domestic legislation in this area and the scientific substantiation of the legal problems that arise there. One of these problems is the essence of subjective responsibility in corporate legal relations.Legislative regulation of corporate legal relations takes place through the establishment of certain rights and responsibilities for ...

  15. Evaluation of mixed-source, low-template DNA profiles in forensic science.

    Science.gov (United States)

    Balding, David J

    2013-07-23

    Enhancements in sensitivity now allow DNA profiles to be obtained from only tens of picograms of DNA, corresponding to a few cells, even for samples subject to degradation from environmental exposure. However, low-template DNA (LTDNA) profiles are subject to stochastic effects, such as "dropout" and "dropin" of alleles, and highly variable stutter peak heights. Although the sensitivity of the newly developed methods is highly appealing to crime investigators, courts are concerned about the reliability of the underlying science. High-profile cases relying on LTDNA evidence have collapsed amid controversy, including the case of Hoey in the United Kingdom and the case of Knox and Sollecito in Italy. I argue that rather than the reliability of the science, courts and commentators should focus on the validity of the statistical methods of evaluation of the evidence. Even noisy DNA evidence can be more powerful than many traditional types of evidence, and it can be helpful to a court as long as its strength is not overstated. There have been serious shortcomings in statistical methods for the evaluation of LTDNA profile evidence, however. Here, I propose a method that allows for multiple replicates with different rates of dropout, sporadic dropins, different amounts of DNA from different contributors, relatedness of suspected and alternate contributors, "uncertain" allele designations, and degradation. R code implementing the method is open source, facilitating wide scrutiny. I illustrate its good performance using real cases and simulated crime scene profiles.

  16. Taylor’s Scientific Management

    Directory of Open Access Journals (Sweden)

    Dimitrios Koumparoulis

    2012-08-01

    Full Text Available Frederick Taylor is known as the father of modern management. Taylor’s scientific management revolutionized industry and helped shape modern organization. Scientific management revolutionized industry because it explains how to increase production by working smarter, not harder. Taylor’s ideas were not limited to only serving the company’s bottom line but the increase in productivity benefited the workforce as well. The principles of scientific management became a machine of universal efficiency since there was a widespread use of scientific management worldwide and beyond the scope of the workplace. Taylor’s theories on using science and statistical fact have become a guideline that many have followed to great success.

  17. For the Anniversary Edition of the Scientific Journal European Researcher. Series A – 110 issue

    Directory of Open Access Journals (Sweden)

    Goran Rajović

    2016-09-01

    Full Text Available This article is a review of the jubilee scientific journal "European Researcher. Series A ", marked at all in 2016 – the sixth anniversary, of regular and of continuous publication. In addition to the history of the newspaper are exposed to the development phase of its program concept. The journal is the period 2010 – 2016 year, profiled in an important factor of development and the formation of professional and scientific thought. Journal “European Research. Series A” is now open forum for publicizing and stimulating innovative thinking on all aspects of the social sciences, the entire international academic community. In all this we emphasize the infinite persistence, creative energy but also authoring and management merits chief editor and founder of the Journal, DrAleksandrCherkasov for survival and development for this great publishing project.

  18. Selected scientific articles. (Investigations in the field of hydrides chemistry and mineral raw materials processing)

    International Nuclear Information System (INIS)

    Mirsaidov, U.M.

    2013-01-01

    Articles, included in the present book are covering period 1977-2013 y. The main scientific articles in the field of power-consuming substances, mineral raw-materials and wastes reprocessing, including uranium industry wastes are collected. Scientific works on hydrogen chemistry which carried out basically bu U.M. Mirsaidov without co-authors are considered. These works are on aluminium hydrides and borohydrides lanthanides. Besides, author's popular-science articles on research carried out by Academy of Sciences during the period when he was the President of Academy of Sciences of the Republic of Tajikistan (1995-2005) are included. Mineral raw materials and wastes reprocessing results are given as well. The book is intended for engineer and technical staff, those working in the field of hydrogen chemistry, hydrometallurgy workers, engineering chemists as well as for PhD, post graduate students and students of appropriate profiles.

  19. Mapping the research on scientific collaboration

    Institute of Scientific and Technical Information of China (English)

    HOU Jianhua; CHEN Chaomei; YAN Jianxin

    2010-01-01

    The aim of this paper was to identify the trends and hot topics in the study of scientific collaboration via scientometric analysis.Information visualization and knowledge domain visualization techniques were adopted to determine how the study of scientific collaboration has evolved.A total of 1,455 articles on scientific cooperation published between 1993 and 2007 were retrieved from the SCI,SSCI and A&HCI databases with a topic search of scientific collaboration or scientific cooperation for the analysis.By using CiteSpace,the knowledge bases,research foci,and research fronts in the field of scientific collaboration were studied.The results indicated that research fronts and research foci are highly consistent in terms of the concept,origin,measurement,and theory of scientific collaboration.It also revealed that research fronts included scientific collaboration networks,international scientific collaboration,social network analysis and techniques,and applications of bibliometrical indicators,webmetrics,and health care related areas.

  20. Teaching scientific concepts through simple models and social communication techniques

    International Nuclear Information System (INIS)

    Tilakaratne, K.

    2011-01-01

    For science education, it is important to demonstrate to students the relevance of scientific concepts in every-day life experiences. Although there are methods available for achieving this goal, it is more effective if cultural flavor is also added to the teaching techniques and thereby the teacher and students can easily relate the subject matter to their surroundings. Furthermore, this would bridge the gap between science and day-to-day experiences in an effective manner. It could also help students to use science as a tool to solve problems faced by them and consequently they would feel science is a part of their lives. In this paper, it has been described how simple models and cultural communication techniques can be used effectively in demonstrating important scientific concepts to the students of secondary and higher secondary levels by using two consecutive activities carried out at the Institute of Fundamental Studies (IFS), Sri Lanka. (author)