Sample records for science partnership msp

  1. Developing Partnerships between Higher Education Faculty, K-12 Science Teachers, and School Administrators via MSP initiatives: The RITES Model (United States)

    Caulkins, J. L.; Kortz, K. M.; Murray, D. P.


    The Rhode Island Technology Enhanced Science Project (RITES) is a NSF-funded Math and Science Partnership (MSP) project that seeks to improve science education. RITES is, at its core, a unique partnership that fosters relationships between middle and high school science teachers, district and school administrators, higher education (HE) faculty members, and science education researchers. Their common goal is to enhance scientific inquiry, increase classroom technology usage, and improve state level science test scores. In one of the more visible examples of this partnership, middle and high school science teachers work closely with HE science faculty partners to design and teach professional development (PD) workshops. The PD sessions focus on technology-enhanced scientific investigations (e.g. use of probes, online simulations, etc.), exemplify inquiry-based instruction, and relate expert content knowledge. Teachers from these sessions express substantial satisfaction in the program, report increased comfort levels in teaching the presented materials (both via post-workshop surveys), and show significant gains in content knowledge (via pre-post assessments). Other benefits to this kind of partnership, in which K-12 and HE teachers are considered equals, include: 1) K-12 teachers are empowered through interactions with HE faculty and other science teachers in the state; 2) HE instructors become more informed not only about good pedagogical practices, but also practical aspects of teaching science such as engaging students; and 3) the PD sessions tend to be much stronger than ones designed and presented solely by HE scientists, for while HE instructors provide content expertise, K-12 teachers provide expertise in K-12 classroom practice and implementation. Lastly, the partnership is mutually beneficial for the partners involved because both sides learn practical ways to teach science and inquiry at different levels. In addition to HE faculty and K-12 science teacher

  2. 77 FR 70422 - Agency Information Collection Activities; Comment Request; Mathematics and Science Partnerships... (United States)


    ...; Comment Request; Mathematics and Science Partnerships Program: Annual Performance Report AGENCY: Office of... notice will be considered public records. Title of Collection: Mathematics and Science Partnerships... Mathematics and Science Partnerships (MSP) program is a formula grant program to the States in which states...

  3. Intermediate Trends in Math and Science Partnership-Related Changes in Student Achievement with Management Information System Data (United States)

    Dimitrov, Dimiter M.


    This substudy in the evaluation design of the Math and Science Partnership (MSP) Program Evaluation examines student proficiency in mathematics and science for the MSPs' schools in terms of changes across three years (2003/04, 2004/05, and 2005/06) and relationships with MSP-related variables using Management Information System data with the…

  4. Partnership in Computational Science

    Energy Technology Data Exchange (ETDEWEB)

    Huray, Paul G.


    This is the final report for the "Partnership in Computational Science" (PICS) award in an amount of $500,000 for the period January 1, 1993 through December 31, 1993. A copy of the proposal with its budget is attached as Appendix A. This report first describes the consequent significance of the DOE award in building infrastructure of high performance computing in the Southeast and then describes the work accomplished under this grant and a list of publications resulting from it.

  5. Next Generation Science Partnerships (United States)

    Magnusson, J.


    I will provide an overview of the Next Generation Science Standards (NGSS) and demonstrate how scientists and educators can use these standards to strengthen and enhance their collaborations. The NGSS are rich in content and practice and provide all students with an internationally-benchmarked science education. Using these state-led standards to guide outreach efforts can help develop and sustain effective and mutually beneficial teacher-researcher partnerships. Aligning outreach with the three dimensions of the standards can help make research relevant for target audiences by intentionally addressing the science practices, cross-cutting concepts, and disciplinary core ideas of the K-12 science curriculum that drives instruction and assessment. Collaborations between researchers and educators that are based on this science framework are more sustainable because they address the needs of both scientists and educators. Educators are better able to utilize science content that aligns with their curriculum. Scientists who learn about the NGSS can better understand the frameworks under which educators work, which can lead to more extensive and focused outreach with teachers as partners. Based on this model, the International Ocean Discovery Program (IODP) develops its education materials in conjunction with scientists and educators to produce accurate, standards-aligned activities and curriculum-based interactions with researchers. I will highlight examples of IODP's current, successful teacher-researcher collaborations that are intentionally aligned with the NGSS.

  6. A Statewide Partnership for Implementing Inquiry Science (United States)

    Lytle, Charles

    The North Carolina Infrastructure for Science Education (NC-ISE) is a statewide partnership for implementing standards-based inquiry science using exemplary curriculum materials in the public schools of North Carolina. North Carolina is the 11th most populous state in the USA with 8,000,000 residents, 117 school districts and a geographic area of 48,718 miles. NC-ISE partners include the state education agency, local school systems, three branches of the University of North Carolina, the state mathematics and science education network, businesses, and business groups. The partnership, based upon the Science for All Children model developed by the National Science Resources Centre, was initiated in 1997 for improvement in teaching and learning of science and mathematics. This research-based model has been successfully implemented in several American states during the past decade. Where effectively implemented, the model has led to significant improvements in student interest and student learning. It has also helped reduce the achievement gap between minority and non-minority students and among students from different economic levels. A key program element of the program is an annual Leadership Institute that helps teams of administrators and teachers develop a five-year strategic plan for their local systems. Currently 33 of the117 local school systems have joined the NC-ISE Program and are in various stages of implementation of inquiry science in grades K-8.

  7. Evaluating RITES, a Statewide Math and Science Partnership Program (United States)

    Murray, D. P.; Caulkins, J. L.; Burns, A. L.; de Oliveira, G.; Dooley, H.; Brand, S.; Veeger, A.


    The Rhode Island Technology-Enhanced Science project (RITES) is a NSF-MSP Program that seeks to improve science education by providing professional development to science teachers at the 5th through 12th grade levels. At it's heart, RITES is a complex, multifaceted project that is challenging to evaluate because of the nature of its goal: the development of a large, statewide partnership between higher education and K12 public school districts during a time when science education strategies and leadership are in flux. As a result, these difficulties often require flexibility and creativity regarding evaluation, study design and data collection. In addition, the research agenda of the project often overlaps with the evaluator's agenda, making collaboration and communication a crucial component of the project's success. In it's 5th year, RITES and it's evaluators have developed a large number of instruments, both qualitative and quantitative, to provide direction and feedback on the effectiveness of the project's activities. RITES personnel work closely with evaluators and researchers to obtain a measure of how RITES' 'theory-of-action' affects both student outcomes and teacher practice. Here we discuss measures of teacher and student content gains, student inquiry gains, and teacher implementation surveys. Using content questions based on AAAS and MOSART databases, teachers in the short courses and students in classrooms showed significant normalized learning gains with averages generally above 0.3. Students of RITES-trained teachers also outperformed their non-RITES peers on the inquiry-section of the NECAP test, and The results show, after controlling for race and economic status, a small but statistically significant increase in test scores for RITES students. Technology use in the classroom significantly increased for teachers who were 'expected implementers' where 'expected implementers' are those teachers who implemented RITES as the project was designed. This

  8. Earth System Science Education Interdisciplinary Partnerships (United States)

    Ruzek, M.; Johnson, D. R.


    Earth system science in the classroom is the fertile crucible linking science with societal needs for local, national and global sustainability. The interdisciplinary dimension requires fruitful cooperation among departments, schools and colleges within universities and among the universities and the nation's laboratories and agencies. Teaching and learning requires content which brings together the basic and applied sciences with mathematics and technology in addressing societal challenges of the coming decades. Over the past decade remarkable advances have emerged in information technology, from high bandwidth Internet connectivity to raw computing and visualization power. These advances which have wrought revolutionary capabilities and resources are transforming teaching and learning in the classroom. With the launching of NASA's Earth Observing System (EOS) the amount and type of geophysical data to monitor the Earth and its climate are increasing dramatically. The challenge remains, however, for skilled scientists and educators to interpret this information based upon sound scientific perspectives and utilize it in the classroom. With an increasing emphasis on the application of data gathered, and the use of the new technologies for practical benefit in the lives of ordinary citizens, there comes the even more basic need for understanding the fundamental state, dynamics, and complex interdependencies of the Earth system in mapping valid and relevant paths to sustainability. Technology and data in combination with the need to understand Earth system processes and phenomena offer opportunities for new and productive partnerships between researchers and educators to advance the fundamental science of the Earth system and in turn through discovery excite students at all levels in the classroom. This presentation will discuss interdisciplinary partnership opportunities for educators and researchers at the undergraduate and graduate levels.

  9. The Ohio Partnership for the Far East Region Science Teachers (United States)

    Beiersdorfer, Raymond; Sturrus, W. Gregg


    The Ohio Partnership for Far East Region Science Teachers (OPFERST) is a three-year project funded by Federal Math Science Partnership Funds through a grant to the Ohio Dept. of Education. OPFERST is a partnership ( of Youngstown State University science and education faculty, trained facilitators and the county and city science consultants. Every (47) school district in the region signed on and during the first year 32 districts participated. During the first two years, 198 teachers representing Ashtabula, Columbiana, Mahoning and Trumbull Counties, as well as Warren City and Youngstown City schools have participated. The vision of OPFERST is to improve the teaching and learning of the Ohio Science Academic Content Standards. Project goals are: 1) Increase science content knowledge of teachers; 2) Implement effective instructional practices; 3) Improve students performance in science; and 4) Develop professional learning communities which will lead to programmatic changes within districts. Goals one through three are met by modeling inquiry-based methods for teaching science content standards. Goal four is met by ongoing meetings through-out the school year, classroom visits by YSU faculty and fieldtrips to the YSU Campus by classes led by OPFERST teachers. Evaluation of OPFERST includes demographic and classroom practice data, pre- and post-tests of participants, journals, homework and the administration of evaluation instruments with some OPFERST participants' students.

  10. Redefining Scientist-Educator Partnerships: Science in Service at Stanford (United States)

    Beck, K.


    The Stanford Solar Observatories Group and Haas Center for Public Service have created an innovative model for scientist-educator partnerships in which science students are trained and mentored by public service education professionals to create outreach events for local communities. The program, Science in Service, is part of the EPO plan for the Solar Group's participation in NASA's Solar Dynamics Observatory mission. Based on the principles of service learning, the Science in Service Program mentors college science students in best practices for communicating science and engages these students in public service projects that center on teaching solar science. The program goals are to - Enhance and expand the learning experiences that pre-college students, from underserved and underrepresented groups in particular, have in science and technology. - Promote leadership in community service in the area of science and engineering among the next generation of scientists and engineers, today's undergraduate students. - Encourage science and engineering faculty to think creatively about their outreach requirements and to create a community of faculty committed to quality outreach programs. This talk will describe the unique advantages and challenges of a research-public service partnership, explain the structure of Stanford's Science in Service Program, and present the experiences of the undergraduates and the outreach communities that have been involved in the program.

  11. Building Ocean Learning Communities: A COSEE Science and Education Partnership (United States)

    Robigou, V.; Bullerdick, S.; Anderson, A.


    The core mission of the Centers for Ocean Sciences Education Excellence (COSEE) is to promote partnerships between research scientists and educators through a national network of regional and thematic centers. In addition, the COSEEs also disseminate best practices in ocean sciences education, and promote ocean sciences as a charismatic interdisciplinary vehicle for creating a more scientifically literate workforce and citizenry. Although each center is mainly funded through a peer-reviewed grant process by the National Science Foundation (NSF), the centers form a national network that fosters collaborative efforts among the centers to design and implement initiatives for the benefit of the entire network and beyond. Among these initiatives the COSEE network has contributed to the definition, promotion, and dissemination of Ocean Literacy in formal and informal learning settings. Relevant to all research scientists, an Education and Public Outreach guide for scientists is now available at This guide highlights strategies for engaging scientists in Ocean Sciences Education that are often applicable in other sciences. To address the challenging issue of ocean sciences education informed by scientific research, the COSEE approach supports centers that are partnerships between research institutions, formal and informal education venues, advocacy groups, industry, and others. The COSEE Ocean Learning Communities, is a partnership between the University of Washington College of Ocean and Fishery Sciences and College of Education, the Seattle Aquarium, and a not-for-profit educational organization. The main focus of the center is to foster and create Learning Communities that cultivate contributing, and ocean sciences-literate citizens aware of the ocean's impact on daily life. The center is currently working with volunteer groups around the Northwest region that are actively involved in projects in the marine environment and to empower these diverse groups


    Directory of Open Access Journals (Sweden)

    I. Mazur


    Full Text Available In the article the cooperation of higher education, science and business is analysed. A conflict of civilizations wave development in the confrontation of two forces: the "factory of Education" and force change is disclosed. European and Ukrainian higher education quality estimation is analysed. The effect of unsynchronization in time is educed between the necessities of business and possibilities of education and science. Reasons of bribery are exposed at higher school. The development strategy of partnership of higher education, science and business is proposed.

  13. Technology-Enhanced Science Partnership Initiative: Impact on Secondary Science Teachers (United States)

    Ng, Wan; Fergusson, Jennifer


    The issue of student disengagement in school science continues to pose a threat to lifting the participation rates of students undertaking STEM courses and careers in Australia and other countries globally. In Australia, several science initiatives to reverse the problem have been funded over the last two decades. Many of these initiatives involve partnerships with scientists, science educators and with industries, as is the case in this paper. The research in this paper investigated a recent partnership initiative between secondary science teachers, scientists and an educational technology company to produce science e-modules on adaptive learning platforms, enabling students to engage in personalised, inquiry-based learning and the investigation of real-world problems. One of the objectives of the partnership project was to build theoretical and pedagogical skills in teachers to deliver science by exposing them to new ways of engaging students with new digital tools, for example analytics. Using a mixed methods approach, the research investigated science teachers' pedagogical involvement in the partnership project and their perceptions of the project's impact on their teaching and students' learning. The findings indicate that the teachers believed that new technology could enhance their teaching and students' learning and that while their students were motivated by the online modules, there was still a need for scaffolding for many of the students. The effectiveness of this would depend on the teachers' ability to internalise the new technological and content knowledge resulting from the partnership and realign them with their existing pedagogical framework. The research is significant in identifying elements for successful partnership projects as well as challenges that need to be considered. It is significant in facilitating continuous discourse about new evidence-based pedagogical approaches to science education in engaging students to learn STEM subjects in a

  14. Enabling Arctic Research Through Science and Engineering Partnerships (United States)

    Kendall, E. A.; Valentic, T. A.; Stehle, R. H.


    Under an Arctic Research Support and Logistics contract from NSF (GEO/PLR), SRI International, as part of the CH2M HILL Polar Services (CPS) program, forms partnerships with Arctic research teams to provide data transfer, remote operations, and safety/operations communications. This teamwork is integral to the success of real-time science results and often allows for unmanned operations which are both cost-effective and safer. The CPS program utilizes a variety of communications networks, services and technologies to support researchers and instruments throughout the Arctic, including Iridium, VSAT, Inmarsat BGAN, HughesNet, TeleGreenland, radios, and personal locator beacons. Program-wide IT and communications limitations are due to the broad categories of bandwidth, availability, and power. At these sites it is essential to conserve bandwidth and power through using efficient software, coding and scheduling techniques. There are interesting new products and services on the horizon that the program may be able to take advantage of in the future such as Iridium NEXT, Inmarsat Xpress, and Omnispace mobile satellite services. Additionally, there are engineering and computer software opportunities to develop more efficient products. We will present an overview of science/engineering partnerships formed by the CPS program, discuss current limitations and identify future technological possibilities that could further advance Arctic science goals.

  15. Building sustained partnerships in Greenland through shared science (United States)

    Culler, L. E.; Albert, M. R.; Ayres, M. P.; Grenoble, L. A.; Virginia, R. A.


    Greenland is a hotspot for polar environmental change research due to rapidly changing physical and ecological conditions. Hundreds of international scientists visit the island each year to carry out research on diverse topics ranging from atmospheric chemistry to ice sheet dynamics to Arctic ecology. Despite the strong links between scientific, social, and political issues of rapid environmental change in Greenland, communication with residents of Greenland is often neglected by researchers. Reasons include language barriers, difficulties identifying pathways for communication, balancing research and outreach with limited resources, and limited social and cultural knowledge about Greenland by scientists. Dartmouth College has a legacy of work in the Polar Regions. In recent years, a National Science Foundation (NSF) Integrative Graduate Education and Research Traineeship (IGERT) in Polar Environmental Change funded training for 25 Ph.D. students in the Ecology, Earth Science, and Engineering graduate programs at Dartmouth. An overarching goal of this program is science communication between these disciplines and to diverse audiences, including communicating about rapid environmental change with students, residents, and the government of Greenland. Students and faculty in IGERT have been involved in the process of engaging with and sustaining partnerships in Greenland that support shared cultural and educational experiences. We have done this in three ways. First, a key component of our program has been hosting students from Ilisimatusarfik (the University of Greenland). Since 2009, five Greenlandic students have come to Dartmouth and formed personal connections with Dartmouth students while introducing their Greenlandic culture and language (Kalaallisut). Second, we have used our resources to extend our visits to Greenland, which has allowed time to engage with the community in several ways, including sharing our science via oral and poster presentations at Katuaq

  16. NOAA's Big Data Partnership and Applications to Ocean Sciences (United States)

    Kearns, E. J.


    New opportunities for the distribution of NOAA's oceanographic and other environmental data are being explored through NOAA's Big Data Partnership (BDP) with Amazon Web Services, Google Cloud Platform, IBM, Microsoft Corp. and the Open Cloud Consortium. This partnership was established in April 2015 through Cooperative Research and Development Agreements, and is seeking new, financially self-sustaining collaborations between the Partners and the federal government centered upon NOAA's data and their potential value in the information marketplace. We will discuss emerging opportunities for collaboration among businesses and NOAA, progress in making NOAA's ocean data more widely accessible through the Partnerships, and applications based upon this access to NOAA's data.

  17. How behavioural science can contribute to health partnerships: the case of The Change Exchange. (United States)

    Byrne-Davis, Lucie M T; Bull, Eleanor R; Burton, Amy; Dharni, Nimarta; Gillison, Fiona; Maltinsky, Wendy; Mason, Corina; Sharma, Nisha; Armitage, Christopher J; Johnston, Marie; Byrne, Ged J; Hart, Jo K


    Health partnerships often use health professional training to change practice with the aim of improving quality of care. Interventions to change practice can learn from behavioural science and focus not only on improving the competence and capability of health professionals but also their opportunity and motivation to make changes in practice. We describe a project that used behavioural scientist volunteers to enable health partnerships to understand and use the theories, techniques and assessments of behavioural science. This paper outlines how The Change Exchange, a collective of volunteer behavioural scientists, worked with health partnerships to strengthen their projects by translating behavioural science in situ. We describe three case studies in which behavioural scientists, embedded in health partnerships in Uganda, Sierra Leone and Mozambique, explored the behaviour change techniques used by educators, supported knowledge and skill development in behaviour change, monitored the impact of projects on psychological determinants of behaviour and made recommendations for future project developments. Challenges in the work included having time and space for behavioural science in already very busy health partnership schedules and the difficulties in using certain methods in other cultures. Future work could explore other modes of translation and further develop methods to make them more culturally applicable. Behavioural scientists could translate behavioural science which was understood and used by the health partnerships to strengthen their project work.

  18. Partnerships

    CERN Multimedia

    Staff Association


    Go Sport Free prize draw    Win Go Sport vouchers by participating in a prize draw of the Staff Association! Thanks to our partnership, 30 vouchers of 50 euros each have been offered to us. To reward you for your loyalty, the Staff Association, organizes a free prize draw for its members. The 30 people who will specify a number that comes closest to the total number of participants to this draw will win a voucher. Deadline for participation: Monday 14th July 2014 – 2 p.m. To participate: Upon presentation of the Staff Association membership card Go Sport Val Thoiry offers a 15 % discount on all purchases in the shop (excluding promotions, sale items and bargain corner, and excluding purchases using Go Sport and Kadéos gift cards. Only one discount can be applied to each purchase). The manager of Go Sport Val Thoiry hands the discount vouchers to the presid...

  19. Translational science matters: forging partnerships between biomedical and behavioral science to advance the public's health. (United States)

    Mensah, George A; Czajkowski, Susan M


    The prevention and effective treatment of many chronic diseases such as cardiovascular disease, cancer and diabetes are dependent on behaviors such as not smoking, adopting a physically-active lifestyle, eating a healthy diet, and adhering to prescribed medical and behavioral regimens. Yet adoption and maintenance of these behaviors pose major challenges for individuals, their families and communities, as well as clinicians and health care systems. These challenges can best be met through the integration of the biomedical and behavioral sciences that is achieved by the formation of strategic partnerships between researchers and practitioners in these disciplines to address pressing clinical and public health problems. The National Institutes of Health has supported a number of clinical trials and research initiatives that demonstrate the value of biomedical and behavioral science partnerships in translating fundamental discoveries into significant improvements in health outcomes. We review several such examples of collaborations between biomedical and behavioral researchers, describe key initiatives focused on advancing a transdisciplinary translational perspective, and outline areas which require insights, tools and findings from both the biomedical and behavioral sciences to advance the public's health.

  20. Northern Eurasia Earth Science Partnership Initiative: evolution of scientific investigations to applicable science

    International Nuclear Information System (INIS)

    Soja, Amber J; Groisman, Pavel Ya


    The letters collected in this focus issue of Environmental Research Letters on ‘Environmental, socio-economic and climatic changes in Northern Eurasia and their feedbacks to the global Earth system’ represent the third special issue based on the results of research within the Northern Eurasia Earth Science Partnership Initiative (NEESPI: program domain. Through the years, NEESPI researchers have presented a diverse array of articles that represent a variety of spatial scales and demonstrate the degree to which abrupt climatic and socio-economic changes are acting across Northern Eurasia and feed back to the global Earth system. (synthesis and review)

  1. Translating Current Science into Materials for High School via a Scientist-Teacher Partnership (United States)

    Brown, Julie C.; Bokor, Julie R.; Crippen, Kent J.; Koroly, Mary Jo


    Scientist-teacher partnerships are a unique form of professional development that can assist teachers in translating current science into classroom instruction by involving them in meaningful collaborations with university researchers. However, few reported models aim to directly alter science teachers' practices by supporting them in the…

  2. University-School Partnerships: Pre-Service and In-Service Teachers Working Together to Teach Primary Science (United States)

    Kenny, John Daniel


    This paper reports on a partnership approach preparing pre-service primary teachers to teach science. Partnerships involving pre-service teachers and volunteer in-service colleagues were formed to teach science in the classroom of the colleague, with support from the science education lecturer. Each pre-service teacher collaboratively planned and…

  3. International Collaborative Research Partnerships: Blending Science with Management and Diplomacy. (United States)

    Lau, Chuen-Yen; Wang, Crystal; Orsega, Susan; Tramont, Edmund C; Koita, Ousmane; Polis, Michael A; Siddiqui, Sophia


    As globalization progressively connects and impacts the health of people across the world, collaborative research partnerships provide mutual advantages by sharing knowledge and resources to address locally and globally relevant scientific and public health questions. Partnerships undertaken for scientific research are similar to business collaborations in that they require attention to partner systems, whether local, international, political, academic, or non-academic. Scientists, like diplomats or entrepreneurs, are representatives of their field, culture, and country and become obligatory agents in health diplomacy. This role significantly influences current and future collaborations with not only the immediate partner but with other in country partners as well. Research partnerships need continuous evaluation of the collaboration's productivity, perspectives of all partners, and desired outcomes for success to avoid engaging in "research tourism", particularly in developing regions. International engagement is a cornerstone in addressing the impact of infectious diseases globally. Global partnerships are strategically aligned with national, partner and global health priorities and may be based on specific requests for assistance from the partnering country governments. Here we share experiences from select research collaborations to highlight principles that we have found key in building long-term relationships with collaborators and in meeting the aim to address scientific questions relevant to the host country and strategic global health initiatives.

  4. Systemic Thinking and Partnership Working: A Cross Sectional Study in a Medical Sciences University in Iran

    Directory of Open Access Journals (Sweden)

    Mohammad Khammarnia


    Full Text Available Background: Systemic thinking can provide practice in multidisciplinary team working and improve the organizational efficacy. This study aimed to determine the association between systemic thinking and partnership working in the employees of a medical sciences university in the south of Iran. Methods: A cross-sectional study was performed in Zahedan University of Medical Sciences (ZAUMS in 2015. The study population consisted of all employees in ZAUMS; 370 participants were selected through stratified random sampling. Two standard questionnaires were used for data gathering. The data were analyzed in SPSS (v21 using Pearson, One way ANOVA, and logistic regression. The level of significance was considered as 0.05. Results: In this study, 225 participants (60.8% were female and their mean age was 34.7±8.7. The score of partnership working for 362 participants was higher than the mean standard (40. Systemic thinking had a positive association with partnership working (p=0.001 and married status of the participants (p=0.04. Partnership working in male and older staff was more than others in ZAUMS (p<0.001 and p=0.01, respectively. Conclusion: Systematic thinking had a positive association with the employees’ working partnership. Moreover, the male staff had better systematic thinking. It is recommended that the managers should promote systematic thinking in staff, especially in females, for better partnership and efficacy in organizations.

  5. Businesses assisting K--12 science instruction: Four case studies of long-term school partnerships (United States)

    van Trieste, Lynne M.

    Businesses lack enough qualified applicants to fill the increasing need for scientists and engineers while educators lack many resources for science programs in K-12 schools. This series of case studies searched for successful collaborations between the two in four geographic locations: Boise, Idaho; Dallas, Texas; Los Angeles County, California, and Orange County, California. These science education partnerships were investigated to gain an understanding of long-term partnership structure, functioning and evaluation methods. Forty-nine individual interviews with representatives from the groups of stakeholders these programs impact were also conducted. Stakeholder groups included students, teachers, parents, school administrators, business liaisons, and non-profit representatives. Several recurring themes in these partnerships reinforced the existing literature research findings. Collaboration and communication between partners, teacher professional development, the need for more minority and female representation in physical science careers, and self-efficacy in relation to how people come to view their scientific abilities, are among these themes. Topics such as program replication, the importance of role models, programs using "hands-on" activities, reward systems for program participants, and program outcome measurement also emerged from the cases investigated. Third-party assistance by a non-profit entity is occurring within all of these partnerships. This assistance ranges from a service providing material resources such as equipment, lesson plans and meeting space, to managing the partnership fundraising, program development and evaluations. Discussions based upon the findings that support or threaten sustainment of these four partnerships, what a "perfect" partnership might look like, and areas in need of further investigation conclude this study.

  6. NASA Earth Science Partnerships - The Role and Value of Commercial and Non-Profit Partnerships with Government in the Earth Sciences (United States)

    Favors, J.; Cauffman, S.; Ianson, E.; Kaye, J. A.; Friedl, L.; Green, D. S.; Lee, T. J.; Murphy, K. J.; Turner, W.


    NASA's Earth Science Division (ESD) seeks to develop a scientific understanding of the Earth as a dynamic, integrated system of diverse components that interact in complex ways - analogous to the human body. The Division approaches this goal through a coordinated series of satellite and airborne missions, sponsored basic and applied research, and technology development. Integral to this approach are strong collaborations and partnerships with a spectrum of organizations with technical and non-technical expertise. This presentation will focus on a new commercial and non-profit partnership effort being undertaken by ESD to integrate expertise unique to these sectors with expertise at NASA to jointly achieve what neither group could alone. Highlights will include case study examples of joint work with perspectives from both NASA and the partner, building interdisciplinary teams with diverse backgrounds but common goals (e.g., economics and Earth observations for valuing natural capital), partnership successes and challenges in the co-production of science and applications, utilizing partner networks to amplify project outcomes, and how involving partners in defining the project scope drives novel and unique scientific and decision-making questions to arise.

  7. U.S. National forests adapt to climate change through science-management partnerships (United States)

    Jeremy S. Littell; David L. Peterson; Constance I. Millar; Kathy A. O' Halloran


    Developing appropriate management options for adapting to climate change is a new challenge for land managers, and integration of climate change concepts into operational management and planning on United States national forests is just starting. We established science-management partnerships on the Olympic National Forest (Washington) and Tahoe National Forest (...

  8. Responding to complex societal challenges: A decade of Earth System Science Partnership (ESSP) interdisciplinary research

    NARCIS (Netherlands)

    Ignaciuk, A.; Rice, M.; Bogardi, J.; Canadell, J.G.; Dhakal, S.; Ingram, J.; Leemans, R.; Rosenberg, M.


    The Earth system is an integrated, self-regulating system under increasing pressure from anthropogenic transformation. The Earth System Science Partnership (ESSP), which was established by the international global environmental change research programs (i.e., DIVERSITAS, IGBP, IHDP and WCRP)

  9. The Southern Nevada Agency Partnership Science and Research Synthesis: Science to support land management in Southern Nevada (United States)

    Jeanne C. Chambers; Matthew L. Brooks; Burton K. Pendleton; Carol B. Raish


    This synthesis provides information related to the Southern Nevada Agency Partnership (SNAP) Science and Research Strategy Goal 1 - to restore, sustain and enhance southern Nevada’s ecosystems - and Goal 2 - to provide for responsible use of southern Nevada’s lands in a manner that preserves heritage resources and promotes an understanding of human interaction with the...

  10. The Southern Nevada Agency Partnership Science and Research Synthesis: Science to support land management in Southern Nevada - Executive Summary (United States)

    Jeanne C. Chambers; Matthew L. Brooks; Burton K. Pendleton; Carol B. Raish


    This synthesis provides information related to the Southern Nevada Agency Partnership (SNAP) Science and Research Strategy Goal 1 - to restore, sustain and enhance southern Nevada’s ecosystems - and Goal 2 - to provide for responsible use of southern Nevada’s lands in a manner that preserves heritage resources and promotes an understanding of human interaction with the...

  11. Analyzing the Watershed Dynamics project as an example of successful science and education partnerships (United States)

    Buzby, C. K.; Jona, K.


    The Watershed Dynamics project is a partnership between Northwestern University, the Consortium of Universities for the Advancement of Hydrologic Science (CUAHSI), and the GLOBE Program (Global Learning and Observations to Benefit the Environment). The goal of the project is to develop inquiry-based educational materials that use authentic scientific data and analysis techniques to teach students about the watershed. The relationship between Northwestern, CUAHSI, and GLOBE allows each partner to contribute to the development of the project in the area of their expertise. Science researchers from CUAHSI share science content knowledge and data access through the development of their Hydrologic Information System (HIS). Curriculum developers at Northwestern write inquiry-based curriculum using GIS technology to access and analyze live data. The GLOBE Program is a worldwide hands-on, primary and secondary school-based science education program that provides teacher training opportunities to a network of teachers around the world. This partnership allows each partner to bring their area of expertise to the project and make the best use of one another's resources. The Watershed Dynamics project can serve as a model for future partnerships between the science and education communities. The Office of Science, Technology, Engineering, and Math Education Partnerships (OSEP) at Northwestern is a service organization that supports Northwestern researchers in developing proposals and implementing research projects that incorporate K-12 educational components, particularly in the fields of science, technology, engineering and mathematics (STEM). OSEP assists faculty with the development of sound plans for education and outreach that reflect current research on learning and educational reform and provides expertise in STEM education materials development, learning technologies, and professional development for K-12 teachers and facilitators in informal education institutions

  12. The North Cascadia Adaptation Partnership: A Science-Management Collaboration for Responding to Climate Change

    Directory of Open Access Journals (Sweden)

    Crystal L. Raymond


    Full Text Available The U.S. Forest Service (USFS and National Park Service (NPS have highlighted climate change as an agency priority and issued direction to administrative units for responding to climate change. In response, the USFS and NPS initiated the North Cascadia Adaptation Partnership (NCAP in 2010. The goals of the NCAP were to build an inclusive partnership, increase climate change awareness, assess vulnerability, and develop science-based adaptation strategies to reduce these vulnerabilities. The NCAP expanded previous science-management partnerships on federal lands to a larger, more ecologically and geographically complex region and extended the approach to a broader range of stakeholders. The NCAP focused on two national forests and two national parks in the North Cascades Range, Washington (USA, a total land area of 2.4 million ha, making it the largest science-management partnership of its kind. The NCAP assessed climate change vulnerability for four resource sectors (hydrology and access; vegetation and ecological disturbance; wildlife; and fish and developed adaptation options for each sector. The NCAP process has proven to be a successful approach for implementing climate change adaptation across a region and can be emulated by other land management agencies in North America and beyond.

  13. Partnerships for the Design, Conduct, and Analysis of Effectiveness, and Implementation Research: Experiences of the Prevention Science and Methodology Group (United States)

    Brown, C. Hendricks; Kellam, Sheppard G.; Kaupert, Sheila; Muthén, Bengt O.; Wang, Wei; Muthén, Linda K.; Chamberlain, Patricia; PoVey, Craig L.; Cady, Rick; Valente, Thomas W.; Ogihara, Mitsunori; Prado, Guillermo J.; Pantin, Hilda M.; Gallo, Carlos G.; Szapocznik, José; Czaja, Sara J.; McManus, John W.


    What progress prevention research has made comes through strategic partnerships with communities and institutions that host this research, as well as professional and practice networks that facilitate the diffusion of knowledge about prevention. We discuss partnership issues related to the design, analysis, and implementation of prevention research and especially how rigorous designs, including random assignment, get resolved through a partnership between community stakeholders, institutions, and researchers. These partnerships shape not only study design, but they determine the data that can be collected and how results and new methods are disseminated. We also examine a second type of partnership to improve the implementation of effective prevention programs into practice. We draw on social networks to studying partnership formation and function. The experience of the Prevention Science and Methodology Group, which itself is a networked partnership between scientists and methodologists, is highlighted. PMID:22160786

  14. Building community partnerships to implement the new Science and Engineering component of the NGSS (United States)

    Burke, M. P.; Linn, F.


    Partnerships between science professionals in the community and professional educators can help facilitate the adoption of the Next Generation Science Standards (NGSS). Classroom teachers have been trained in content areas but may be less familiar with the new required Science and Engineering component of the NGSS. This presentation will offer a successful model for building classroom and community partnerships and highlight the particulars of a collaborative lesson taught to Rapid City High School students. Local environmental issues provided a framework for learning activities that encompassed several Crosscutting Concepts and Science and Engineering Practices for a lesson focused on Life Science Ecosystems: Interactions, Energy, and Dynamics. Specifically, students studied local water quality impairments, collected and measured stream samples, and analyzed their data. A visiting hydrologist supplied additional water quality data from ongoing studies to extend the students' datasets both temporally and spatially, helping students to identify patterns and draw conclusions based on their findings. Context was provided through discussions of how science professionals collect and analyze data and communicate results to the public, using an example of a recent bacterial contamination of a local stream. Working with Rapid City High School students added additional challenges due to their high truancy and poverty rates. Creating a relevant classroom experience was especially critical for engaging these at-risk youth and demonstrating that science is a viable career path for them. Connecting science in the community with the problem-solving nature of engineering is a critical component of NGSS, and this presentation will elucidate strategies to help prospective partners maneuver through the challenges that we've encountered. We recognize that the successful implementation of the NGSS is a challenge that requires the support of the scientific community. This partnership

  15. Science and Societal Partnerships to Address Cumulative Impacts


    Lundquist, Carolyn J.; Fisher, Karen T.; Le Heron, Richard; Lewis, Nick I.; Ellis, Joanne I.; Hewitt, Judi E.; Greenaway, Alison J.; Cartner, Katie J.; Burgess-Jones, Tracey C.; Schiel, David R.; Thrush, Simon F.


    Funding and priorities for ocean research are not separate from the underlying sociological, economic, and political landscapes that determine values attributed to ecological systems. Here we present a variation on science prioritization exercises, focussing on inter-disciplinary research questions with the objective of shifting broad scale management practices to better address cumulative impacts and multiple users. Marine scientists in New Zealand from a broad range of scientific and social...

  16. STEM Education and Leadership: A Mathematics and Science Partnership Approach


    Twyford, John; Järvinen, Esa-Matti


    The issue of attracting more young people to choose careers in science, technology, engineering, and mathematics (STEM) has become critical for the United States. Recent studies by businesses, associations, and education have all agreed that the United States’ performance in the STEM disciplines have placed our nation in grave risk of relinquishing its competitive edge in the marketplace (e.g., Rising above the gathering storm, 2007). A Congressional Research Service (2006) report stated that...

  17. Science and societal partnerships to address cumulative impacts

    Directory of Open Access Journals (Sweden)

    Carolyn J Lundquist


    Full Text Available Funding and priorities for ocean research are not separate from the underlying sociological, economic, and political landscapes that determine values attributed to ecological systems. Here we present a variation on science prioritisation exercises, focussing on inter-disciplinary research questions with the objective of shifting broad scale management practices to better address cumulative impacts and multiple users. Marine scientists in New Zealand from a broad range of scientific and social-scientific backgrounds ranked 48 statements of research priorities. At a follow up workshop, participants discussed five over-arching themes based on survey results. These themes were used to develop mechanisms to increase the relevance and efficiency of scientific research while acknowledging socio-economic and political drivers of research agendas in New Zealand’s ocean ecosystems. Overarching messages included the need to: 1 determine the conditions under which ‘surprises’ (sudden and substantive undesirable changes are likely to occur and the socio-ecological implications of such changes; 2 develop methodologies to reveal the complex and cumulative effects of change in marine systems, and their implications for resource use, stewardship, and restoration; 3 assess potential solutions to management issues that balance long-term and short-term benefits and encompass societal engagement in decision-making; 4 establish effective and appropriately resourced institutional networks to foster collaborative, solution-focused marine science; and 5 establish cross-disciplinary dialogues to translate diverse scientific and social-scientific knowledge into innovative regulatory, social and economic practice. In the face of multiple uses and cumulative stressors, ocean management frameworks must be adapted to build a collaborative framework across science, governance and society that can help stakeholders navigate uncertainties and socio-ecological surprises.

  18. Expanding Earth and Space Science through the Initiating New Science Partnerships In Rural Education (INSPIRE) (United States)

    Radencic, S.; McNeal, K. S.; Pierce, D.; Hare, D.


    The INSPIRE program at Mississippi State University (MSU), funded by the NSF Graduate STEM Fellows in K-12 Education (GK12) program, focuses on Earth and Space science education and has partnered ten graduate students from MSU with five teachers from local, rural school districts. For the next five years the project will serve to increase inquiry and technology experiences in science and math while enhancing graduate student’s communication skills. Graduate students, from the disciplines of Geosciences, Physics, and Engineering are partnered with Chemistry, Physical Science, Physics, Geometry and Middle school science classrooms and will create engaging inquiry activities that incorporate elements of their research, and integrate various forms of technology. The generated lesson plans that are implemented in the classroom are published on the INSPIRE home page ( so that other classroom instructors can utilize this free resource. Local 7th -12th grade students will attend GIS day later this fall at MSU to increase their understanding and interest in Earth and Space sciences. Selected graduate students and teachers will visit one of four international university partners located in Poland, Australia, England, or The Bahamas to engage research abroad. Upon return they will incorporate their global experiences into their local classrooms. Planning for the project included many factors important to the success of the partnerships. The need for the program was evident in Mississippi K-12 schools based on low performance on high stakes assessments and lack of curriculum in the Earth and Space sciences. Meeting with administrators to determine what needs they would like addressed by the project and recognizing the individual differences among the schools were integral components to tailoring project goals and to meet the unique needs of each school partner. Time for training and team building of INSPIRE teachers and graduate students before the

  19. Creating Effective Partnerships in Ecosystem-Based Management: A Culture of Science and Management

    Directory of Open Access Journals (Sweden)

    Carlie S. Wiener


    Full Text Available An ecosystem-based management research partnership between the Hawai‘i Institute of Marine Biology and Office of National Marine Sanctuaries, specifically with the Northwestern Hawaiian Islands Coral Reef Ecosystem Reserve and, later, the Papahānaumokuākea Marine National Monument, provides a case study to analyze integration of scientific research into management plans through collaborative communications. Ecosystem-based management seeks input from disparate stakeholders and requires effective communication systems for the public, science, and management partners that bypass differences in organizational culture and communication styles. Here, we examine a successful partnership within the framework of ecosystem-based management to survey and evaluate cultural differences, understand what facilitates collaborative communication, highlight factors that impede a successful partnership, and identify areas for improvement. Effective communication has been achieved through an analysis of the organizations cultures and structures to better define communication links. Although specific differences were noted in organization and style, successful integration was accomplished through techniques such as the development of symposia and semiannual reports. This paper will explore the organizational culture analysis and structure evaluation, which are components of a larger study. This science management integration project is an example of how organizational analysis can lead to recommendations for improved communication and integration of science and management.

  20. Dialectical dividends: fostering hybridity of new pedagogical practices and partnerships in science education and outreach (United States)

    Martins Gomes, Diogo; McCauley, Veronica


    Science literacy has become socially and economically very important. European countries stress that science graduates are fundamental for economic growth. Nevertheless, there is a declining student participation in science. In response, there has been a call to change the way science is taught in schools, which focuses on inquiry methods rooted in constructivism. Universities and other organisations have responded by developing outreach programmes to improve student engagement in science. Given this context, there is a necessity for research to ascertain if this new relationship between outreach and education is worthwhile. This study examines and compares primary teachers and outreach practitioners understanding and perceptions of constructivist science pedagogy, in an effort to understand the potential of a teacher-outreach partnership. For this, qualitative and quantitative methods were employed, taking a dialectic pragmatic stance. Contradicting the recurrent view, teachers and outreach providers revealed favourable views in relation to constructivism, despite recognising barriers to its implementation. These results support a partnership between teachers and outreach practitioners and the realisation of the hybrid role of each participant. The results also reveal an important dynamic in outreach access to schools. Specifically, the outreach connected teachers acted as gatekeepers by negotiating access into their colleagues classrooms.

  1. Creating Science Education Specialists and Scientific Literacy in Students through a Successful Partnership among Scientists, Science Teachers, and Education Researchers (United States)

    Metoyer, S.; Prouhet, T.; Radencic, S.


    The nature of science and the nature of learning are often assumed to have little practical relationship to each other. Scientists conduct research and science teachers teach. Rarely do the scientist and the science teacher have an opportunity to learn from each other. Here we describe results from a program funded by NSF, the Information Technology in Science (ITS) Center for Teaching and Learning. The ITS Center provided the support and structure necessary for successful long-term collaboration among scientists, science teachers, and education researchers that has resulted in the creation of new science education specialists. These specialists are not only among the science teachers, but also include avid recruits to science education from the scientists themselves. Science teachers returned to their classrooms armed with new knowledge of content, inquiry, and ideas for technology tools that could support and enhance students' scientific literacy. Teachers developed and implemented action research plans as a means of exploring educational outcomes of their use and understanding of new technologies and inquiry applied to the classroom. In other words, they tried something different in the class related to authentic inquiry and technology. They then assessed the students' to determine if there was an impact to the students in some way. Many of the scientists, on the other hand, report that they have modified their instructional practices for undergraduate courses based on their experiences with the teachers and the ITS Center. Some joined other collaborative projects pairing scientists and educators. And, many of the scientists continue on-going communication with the science teachers serving as mentors, collaborators, and as an "expert" source for the students to ask questions to. In order to convey the success of this partnership, we illustrate and discuss four interdependent components. First, costs and benefits to the science teacher are discussed through case

  2. A Radio Astronomy Science Education Partnership - GAVRT and Radio JOVE (United States)

    Higgins, C. A.; Thieman, J. R.; Bunnell, K.; Soholt, G.


    The planet Jupiter provides an excellent subject to educate, engage, and inspire students and teachers to learn science. The Goldstone Apple-Valley Radio Telescope (GAVRT) program ( and The Radio JOVE project ( each have a long history of allowing students and teachers to interact with scientists and real radio telescopes. The upcoming Juno mission to Jupiter (2011 launch) allows both GAVRT and Radio JOVE to combine efforts and engage with the NASA Juno mission, thus increasing the excitement and learning potential for teachers, students, and the general public. Teachers can attend workshops for training to operate a 34-meter radio telescope and/or build their own simple radio telescope, both of which can be used directly in the classroom. We will overview some classroom activities and highlight some teacher-student experiences. In addition, we will update our efforts on greater Web-based control of the radio telescopes, as well as highlight our upcoming workshops to allow better access for teachers in different parts of the Country.

  3. 9th Pacific Basin Nuclear Conference. Nuclear energy, science and technology - Pacific partnership. Proceedings Volume 1

    International Nuclear Information System (INIS)


    The theme of the 9th Pacific Basin Nuclear conference held in Sydney from 1-6 May 1994, embraced the use of the atom in energy production and in science and technology. The focus was on selected topics of current and ongoing interest to countries around the Pacific Basin. The two-volume proceedings include both invited and contributed papers. They have been indexed separately. This document, Volume 1 covers the following topics: Pacific partnership; perspectives on nuclear energy, science and technology in Pacific Basin countries; nuclear energy and sustainable development; economics of the power reactors; new power reactor projects; power reactor technology; advanced reactors; radioisotope and radiation technology; biomedical applications

  4. Northern Eurasia Earth Science Partnership Initiative in 2012: An Update (United States)

    Groisman, P. Y.; Lawford, R. G.; Kattsov, V.


    Seven years ago NEESPI was launched with the release of its Science Plan ( Gradually, the Initiative was joined by numerous international projects launched in EU, Russia, the United States, Canada, Japan, and China. Throughout its duration, NEESPI served and is serving as an umbrella for more than 150 individual international research projects. Currently, the Initiative is in full swing. The total number of the ongoing NEESPI projects (as on July 2012) is 50 and has changed but slightly compared to its peak (87 in 2008). The past one and half years (2011 through mid-2012) were extremely productive in the NEESPI outreach. We organized five Open Science Sessions at the three major Geoscience Unions/Assembly Meetings (AGU, EGU, and JpGU) and four International NEESPI Workshops. The programs of two of these Workshops (in Tomsk and Irkutsk, Russia) included Summer Schools for early career scientists. More than 230 peer-reviewed papers, books, and/or book chapters were published or are in press (this list was still incomplete at the time of preparation of this abstract). In particular, a suite of 24 peer-reviewed NEESPI articles was published in the Forth Special NEESPI Issue of "Environmental Research Letters" ( Northern Eurasia is a large study domain. Therefore, it was decided to describe the latest findings related to its environmental changes in several regional monographs in English. Three books on Environmental Changes in the NEESPI domain were published by Springer Publishing. House (Gutman and Reissell, eds., 2011; Groisman and Gutman eds. 2013) and "Naukova Dumka" of Ukraine (Groisman and Lyalko, eds. 2012) being devoted to the high latitudes of Eurasia, to Siberia, and to Eastern Europe respectively. One more book by J. Chen et al. (eds.) Dryland East Asia: Land Dynamics amid Social and Climate Change has been prepared by the members of the NEESPI team for Springer and will be published in

  5. Promoting US-China Critical Zone Science Collaboration and Coordination Through Established Subnational Bilateral Science Partnerships: The US-China EcoPartnership for Economic and Environmental Sustainability. (United States)

    Filley, T. R.; Guo, D.; Plante, A. F.


    The concept of critical zone (CZ) science has gained wide recognition with actively funded and emerging CZ observatory programs across the globe. There is much to be gained through international collaboration that links field, laboratory, and modeling efforts from across the emerging global CZ networks, but building international ties is difficult, especially when peer-to-peer connections are nascent, separated by great distances, and span different cultural and political environments. The U.S. and China share many climatic and geological similarities but differ greatly in the magnitude and timescale of human alteration of their landscapes making the comparative study of their respective pasts, current state, and future co-evolution an outstanding scientific opportunity to better understand, predict, and respond to human influence on the CZ. Leveraging the infrastructure and trust capital of longstanding sub-national volunteer scientific networks to bring together people and organizations is a resource-efficient mechanism to build cross-network CZ programs. The U.S.-China EcoPartnership for Environmental Sustainability (USCEES) is one of 30 current EcoPartnerships established beginning in May 2008 by a joint agreement between the U.S. Department of State and China's National Development and Reform Commission with the overarching goal of addressing the interconnected challenges of environmental, social, and economic sustainability through bi-national research innovation, communication, and entrepreneurship. The 2015 USCEES annual conference on "Critical Zone Science, Sustainability, and Services in a Changing World" was co-sponsored by the U.S. Cross-CZO Working Group on Organic Matter Dynamics and hosted three NSF-funded workshops on organic matter dynamics:1) methods for large and complex data analysis, 2) erosion and deposition processes, and 3) mineralogical and microbial controls on reactivity and persistence. This paper highlights outcomes from the workshops

  6. Building a science of partnership-focused research: forging and sustaining partnerships to support child mental health prevention and services research. (United States)

    Bradshaw, Catherine P; Haynes, Katherine Taylor


    Building on growing interest in translational research, this paper provides an overview of a special issue of Administration and Policy in Mental Health and Mental Health Service Research, which is focused on the process of forging and sustaining partnerships to support child mental health prevention and services research. We propose that partnership-focused research is a subdiscipline of translational research which requires additional research to better refine the theoretical framework and the core principles that will guide future research and training efforts. We summarize some of the major themes across the eight original articles and three commentaries included in the special issue. By advancing the science of partnership-focused research we will be able to bridge the gap between child mental health prevention and services research and practice.

  7. US - India Partnership in Science and Technology, Environment and Health: Opportunities and Challenges

    Energy Technology Data Exchange (ETDEWEB)

    Kulkarni, Satish V [Georgetown University


    Today, the US – India strategic partnership is rooted in shared values and is broad in nature and scope, with our two countries working together on global and energy security, climate change and clean environment, life sciences and public health, economic prosperity and trade, and education. A key outcome of this partnership has been the signing of the historic Indo-US Civil Nuclear Deal. Science and technology (S&T) have always been important elements of this partnership, and US Secretary of State Condoleezza Rice and Indian S&T Minister Kapil Sibal signed an agreement on S&T Cooperation between the two countries in October 2005. In March 2006, recognizing the expanding role of S&T, President George Bush and Prime Minister Manmohan Singh formed a Bi-National S&T Commission and established a Joint S&T Endowment Fund focused on innovation, entrepreneurship and commercialization. In July 2009, US Secretary of State Hillary Clinton and Indian Foreign Minister Krishna signed the Endowment Agreement with a total equivalent funding of $30M (equal contribution from US and India). While these steps take our engagement to new heights, US-India collaboration in S&T is not new and has been ongoing for several decades, principally through agencies like NSF, NIH, EPA, DOE, NASA, NOAA, the PL480 US-India Fund, and the Indian Diaspora. However, acting as a damper, especially during the cold war days, this engagement has been plagued by sanctions and the resulting tensions and mistrust which continue to linger on even today. In this context, several ongoing activities in energy, space, climate change and education will be highlighted. Also, with the S&T and the Civil Nuclear Agreements and climate change as examples, the interplay of science, policy and politics will be discussed.

  8. Developing partnerships for implementing continental-scale citizen science programs at the local-level (United States)

    Newman, S. J.; Henderson, S.; Ward, D.


    Project BudBurst is a citizen science project focused on monitoring plant phenology that resides at the National Ecological Observatory Network (NEON, Inc). A central question for Project BudBurst and other national outreach programs is: what are the most effective means of engaging and connecting with diverse communities throughout the country? How can continental scale programs like NEON's Project BudBurst engage audiences in such a way as to be relevant at both the local and continental scales? Staff with Project BudBurst pursued partnerships with several continental scale organizations: the National Wildlife Refuge System, the National Park Service, and botanic gardens to address these questions. The distributed nature of wildlife refuges, national parks, and botanic gardens around the country provided the opportunity to connect with participants locally while working with leadership at multiple scales. Project BudBurst staff talked with hundreds of staff and volunteers prior to setting a goal of obtaining and developing resources for several Refuge Partners, a pilot National Park partner, and an existing botanic garden partner during 2011. We were especially interested in learning best practices for future partnerships. The partnership efforts resulted in resource development for 12 Refuge partners, a pilot National Park partner, and 2 botanic garden partners. Early on, the importance of working with national level leaders to develop ownership of the partner program and input about resource needs became apparent. Once a framework for the partnership program was laid out, it became critical to work closely with staff and volunteers on the ground to ensure needs were met. In 2012 we began to develop an online assessment to allow our current and potential partners to provide feedback about whether or not the partnership program was meeting their needs and how the program could be improved. As the year progressed, the timeline for resource development became more

  9. Relationship between partnership working and employees’ productivity in a University of Medical Sciences in the South of Iran

    Directory of Open Access Journals (Sweden)

    Mohammad Khammarnia


    Full Text Available Introduction: Partnership working plays an important role in the health system, results in delivery of coordinated packages of services to patients, and reduces the impact of organizational fragmentation. Method: The study aimed to determine the relationship between partnership working and productivity in the employees of a university of medical sciences in the south of Iran. Results: According to the result, partnership and productivity scores were 51.1 + 6.7 and 51.9 + 13.4, respectively. Partnership working had a positive relationship with productivity (r = 0.333, P = 0.001 and age of the employees (r = 0.142, P = 0.007. There was a negative relationship between the employees’ productivity with age and job position in ZAUMS (P= 0.009 and P= 0.001, respectively. The nurses had the highest score of productivity (mean=60.7±13.3. Moreover, employees with an Ph.D. degree (9 persons had the highest scores of partnership and productivity in ZAUMS (53.6±3.1 and 56.8±6.3, respectively. Conclusion: Enhancement of partnership working could increase the employees’ productivity in the health system. It is recommended that younger persons should be used in universities of medical science. Moreover, supportive staff should increase their partnership working to enhance the individual and organizational productivity.

  10. Internetová reklama pro MSP


    Molnár, Peter


    Cielom práce je poukázať na hlavné formy internetovej reklamy, ktoré sa používajú pri reklamných kampaniach. Dalšími cielmi je poukázať na využitie internetovej reklamy z pohladu MSP ako aj návrh reklamnej kampane za použitia internetových foriem reklamy. The aim of this work is to point main forms of internet advertising, used by advertising campaign. The other aims are to point on usage of internet advertising in SME and layout of advertising campaign using internet forms of advertising....

  11. Operationalizing Social Work Science through Research-Practice Partnerships: Lessons from Implementation Science (United States)

    Palinkas, Lawrence A.; He, Amy S.; Choy-Brown, Mimi; Hertel, Amy Locklear


    Recent efforts to identify and promote a distinct science for the discipline of social work have led to an ongoing debate regarding the nature and function of such a science. Central to this debate is a lack of consensus as to how to operationalize a social work science. Drawing from the field of implementation science and its application in…

  12. Science Partnerships for a Sustainable Arctic: the Marine Mammal Nexus (Invited) (United States)

    Moore, S. E.


    Marine mammals are both icons of Arctic marine ecosystems and fundamental to Native subsistence nutrition and culture. Eight species are endemic to the Pacific Arctic, including the polar bear, walrus, ice seals (4 species), beluga and bowhead whales. Studies of walrus and bowheads have been conducted over the past 30 years, to estimate population size and elucidate patterns of movement and abundance. With regard to the three pillars of the SEARCH program, these long-term OBSERVATIONS provide a foundation for research seeking to UNDERSTAND and RESPOND to the effects of rapid climate change on the marine ecosystem. Specifically, research on the coastal ecosystem near Barrow, Alaska focuses on late-summer feeding habitat for bowheads in an area where whales are hunted in autumn. This work is a partnership among agency, academic and local scientists and the residents of Barrow, all of whom seek to better UNDERSTAND how recent dramatic changes in sea ice, winds and offshore industrial activities influence whale movements and behavior. In regard to RESPONDING to climate change, the nascent Sea Ice for Walrus Outlook (SIWO) is a science partnership that projects sea ice and wind conditions for five villages in the Bering Strait region. The objective of the SIWO is to provide information on physical conditions in the marine environment at spatial and temporal scales relevant to walrus hunters. Marine mammals are a strong and dynamic nexus for partnerships among scientists, Arctic residents, resource managers and the general public - as such, they are essential elements to any science plan for a sustainable Arctic.

  13. Creating and Sustaining University-Community Partnerships in Science Education (Invited) (United States)

    Finkelstein, N.


    Despite years of research and investment, we have yet to see the widespread implementation of a myriad research-proven instructional strategies in STEM education[1]. To address this challenge, we present and analyze one such strategy, a theoretically-grounded model of university-community partnership [2] that engages university students and children in a collective enterprise that has the potential to improve the participation and education of all. We document the impact of this effort on: university participants who learn about education, the community and science; children in the community who learn about science, the nature of science and develop their identities and attitudes towards science; and, shifts in institutional structures which may allow these programs to be part of standard practice. This project is designed to be sustained and scaled, and is analyzed through the application of a new framework [3] which brings together theories of STEM change that come from studies in higher education, faculty development and disciplinary-based education research in STEM. [1] National Research Council. (2003). Improving Undergraduate Instruction in Science, Technology, Engineering, and Mathematics: Report of A Workshop. Washington, D.C.: The National Academies Press. [2] Finkelstein, N. and Mayhew, L. (2008). Acting in Our Own Self-Interest: Blending University and Community. Proceedings of the 2008 Physics Education Research Conf, AIP Press. Melville NY, 1064, 19-22. [3] Henderson, C., Finkelstein, N. & Beach A. (to appear). Beyond Dissemination in College science teaching: An Introduction to Four Core Change Strategies. Accepted May 2009 in Journal of College Science Teaching.

  14. How to build science-action partnerships for local land-use planning and management: lessons from Durban, South Africa

    Directory of Open Access Journals (Sweden)

    Jessica Cockburn


    Full Text Available The gap between scientific knowledge and implementation in the fields of biodiversity conservation, environmental management, and climate change adaptation has resulted in many calls from practitioners and academics to provide practical solutions responding effectively to the risks and opportunities of global environmental change, e.g., Future Earth. We present a framework to guide the implementation of science-action partnerships based on a real-world case study of a partnership between a local municipality and an academic institution to bridge the science-action gap in the eThekwini Municipal Area, South Africa. This partnership aims to inform the implementation of sustainable land-use planning, biodiversity conservation, environmental management, and climate change adaptation practice and contributes to the development of human capacity in these areas of expertise. Using a transdisciplinary approach, implementation-driven research is being conducted to develop several decision-making products to better inform land-use planning and management. Lessons learned through this partnership are synthesized and presented as a framework of enabling actions operating at different levels, from the individual to the interorganizational. Enabling actions include putting in place enabling organizational preconditions, assembling a functional well-structured team, and actively building interpersonal and individual collaborative capacity. Lessons learned in the case study emphasize the importance of building collaborative capacity and social capital, and paying attention to the process of transdisciplinary research to achieve more tangible science, management, and policy objectives in science-action partnerships. By documenting and reflecting on the process, this case study provides conceptual and practical guidance on bridging the science-action gap through partnerships.

  15. Academe-Industry Partnership: Basis for Enhanced Learning Guide in the New Science General Education Course

    Directory of Open Access Journals (Sweden)

    Alma D. Agero


    Full Text Available This study explores the academe-industry partnership of Cebu Technological University Bachelor of Science in Hospitality Management and Bachelor of Science in Industrial Technology major in Food Preparation and Services courses, SY 2014-2015 to improve the quality of course offering. It takes on the feedback received from supervisors of 50 different hotels and restaurants of Cebu province, as well as the self-rating of 185 OJTs of the two courses as regard to OJTs' level of functional and science-based core competencies. This descriptive research utilizes Likert-type research-made survey questionnaire which was previously tested for validity and reliability. The findings revealed that industry supervisors evaluated the trainees as Competent in core competencies (Bartending, Bread and pastry products, Cookery, Customer services, Front office services, food and beverages as well as functional skills (Problem solving, Leadership, Communication, Independent work, Creativity, Negotiation, Teamwork, Time management and Initiative. However, they found the students need of strengthening their problem solving and communication skills. The researchers therefore developed an enhanced learning guide for the New Science GE course to address the gaps based on the industry feedback.

  16. WVU--community partnership that provides science and math enrichment for underrepresented high school students. (United States)

    Rye, J A; Chester, A L


    In response to the need to help West Virginia secondary school students overcome educational and economic barriers and to increase the number of health professionals in the state, the Health Sciences and Technology Academy (hereafter, "the Academy") was established in 1994. The Academy is a partnership between West Virginia University (WVU)--including the Robert C. Byrd Health Sciences Center, Eberly College of Arts and Sciences, and the College of Human Resources and Education--and members of the community, including secondary-school teachers, health care professionals, and other community leaders. The Academy targets students from underrepresented groups (mainly African Americans and financially disadvantaged whites) in grades nine through 12. By November 1997, 290 students (69% girls and 33% African American) from 17 counties were Academy participants. Funding is from the W. K. Kellogg Foundation, Howard Hughes Medical Institute, the National Institutes of Health, the Coca-Cola Foundation, and other sources. Academy programs are an on-campus summer institute and community-based clubs, where students engage in activities for science and math enrichment, leadership development, and health careers awareness. In the Academy's clubs, students carry out extended investigations of problems related to human health and local communities. Most students report that the Academy has increased their interest in health care careers, and almost all who have continued to participate in Academy programs through their senior year have been accepted into college.

  17. The Woods Hole Partnership Education Program: Increasing Diversity in the Ocean and Environmental Sciences in One Influential Science Community (United States)

    Jearld, A.


    To increase diversity in one influential science community, a consortium of public and private institutions created the Woods Hole Partnership Education Program, or PEP, in 2008. Participating institutions are the Marine Biological Laboratory, Northeast Fisheries Science Center of NOAA's Fisheries Service, Sea Education Association, U.S. Geological Survey, Woods Hole Oceanographic Institution, the Woods Hole Research Center, and University of Maryland Eastern Shore. Aimed at college juniors and seniors with some course work in marine and/or environmental sciences, PEP is a four-week course and a six-to-eight-week individual research project under the guidance of a research mentor. Forty-six students have participated to date. Investigators from the science institutions serve as course faculty and research mentors. We listened to experts regarding critical mass, mentoring, adequate support, network recruitment, and then built a program based on those features. Three years in we have a program that works and that has its own model for choosing applicants and for matching with mentors. We continue fine-tuning our match process, enhancing mentoring skills, preparing our students for a variety of lab cultures, and setting expectations high while remaining supportive. Our challenges now are to keep at it, using leverage instead of capacity to make a difference. Collaboration, not competition, is key since a rising tide floats all boats.

  18. Photonics outreach and education through partnerships in Puerto Rico (United States)

    Friedman, Jonathan S.; Diaz, Andres; Saltares, Roger; Luciano, Sarah; Molina, Nerivette; Martinez, Smailyn; Hernandez, Alejandro; de Jesus, Johan; Rivera, Yesenia; Capeles, Antonio; Alvear, Felipe; Lopez, Jesus; Rivera, Miguel; Saurez, Rey; Trujillo, Elsa


    As the only photonics center in Puerto Rico, the Puerto Rico Photonics Institute (PRPI) has developed education and outreach projects, partnering with other institutions and private companies to optimize the use of available resources. We present our experience, challenges, rewards, and results for the following projects: - Tours: K-12 students visit our facilities in a science tour including a presentation on the Arecibo Observatory (AO) and the Digital Planet Geodome. We present optics demonstrations and other information. In the first three months we hosted fifteen schools impacting over 1,400 students. - Outreach: We have newly active outreach and recruiting activities for Puerto Rico (PR) schools. - Teachers: With the PR Math-Science Partnership (MSP) Program, we have given a full-day workshop on optics and photonics experiments for 5th-12th grade teachers, and a master class at the annual MSP Congress. We have impacted over 500 teachers through these initiatives. - Continuing Education: We have given continuing education courses in addition to the MSP workshops. - General Public: We partner with museums in PR, the University of Turabo, and the AO Visitor Center to build optics exhibits, many developed by students. - Video: PRPI is promoting the 2015 International Year of Light, creating: 1. A short video with students and faculty from the Universidad Metropolitana (UMET) Schools of Communication and Business Administration; 2. A longer video with the production company Geoambiente. - Apps: Our website will include ray tracing and wave propagation applications, developed by UMET Computer Science students. - Capstone: Engineering students at the School of Engineering at Universidad del Turabo are developing laser pattern generators.

  19. Developing a common strategy for integrative global change research and outreach: the Earth System Science Partnership (ESSP)

    NARCIS (Netherlands)

    Leemans, R.; Asrar, G.; Canadell, J.G.; Ingram, J.; Larigauderie, A.; Mooney, H.; Nobre, C.; Patwardhan, A.; Rice, M.; Schmidt, F.; Seitzinger, S.; Virji, H.; Vörösmarthy, C.; Yuoung, O.


    The Earth System Science Partnership (ESSP) was established in 2001 by four global environmental change (GEC) research programmes: DIVERSITAS, IGBP, IHDP and WCRP. ESSP facilitates the study of the Earth's environment as an integrated system in order to understand how and why it is changing, and to

  20. Earth system science K-12 scientist-student partnerships using paleontological materials (United States)

    Harnik, P. G.; Ross, R. M.; Chiment, J. J.; Sherpa, J. M.


    Reducing the discrepancy between the dynamic science that researchers experience and the static fact-driven science education in which k-12 students participate at school is an important component to national science education reform. Scientist-student partnerships (SSPs) involving whole classes in Earth systems research provide a solution to this problem, but existing models have often lacked rigorous scientific data quality control and/or evaluation of pedagogical effectiveness. The Paleontological Research Institution has been prototyping two SSPs with an eye toward establishing protocols to insure both scientific and educational quality of the partnership. Data quality analysis involves making statistical estimates of data accuracy and employing robust statistical techniques for answering essential questions with noisy data. Educational evaluation takes into account affective variables, such as student motivation and interest, and compares the relative pedagogical effectiveness of SSPs with more traditional hands-on activities. Paleontology is a natural subject for scientist-student partnerships because of its intrinsic appeal to the general public, and because its interdisciplinary content serves as a springboard for meeting science education standards across the physical and life sciences. The "Devonian Seas" SSP involves classes in identifying fossil taxa and assessing taphonomic characteristics from Devonian-aged Hamilton Group shales in Central New York. The scientific purpose of the project is to establish at high stratigraphic resolution the sequence of dysoxic biofacies composition, which will shed light on the sensitivity of epeiric sea communities to environmental (e.g., sea level) changes. The project is undertaken in upper elementary school and secondary school Earth science classes, and in some cases has involved field-based teacher training and collection of samples. Students in small teams collaborate to identify taxa within the samples, then

  1. Exploring the impact of an industrial volunteer/school science partnership on elementary teaching strategies and attitudes about future science study: A case study (United States)

    White, Michael Robert

    This study reports the results of research designed to explore the impact of industrial volunteer/school partnerships on elementary science teaching behaviors and students' attitudes about future science study. Since these partnerships involved teachers and students in hands-on or laboratory-type science experiences, the study will add an elementary school component to a series of other studies conducted through the Science Education Program at Temple University that have addressed how to improve the learning outcomes from these experiences. Three suburban elementary schools were randomly selected by a single school district's science supervisor to be involved in this study. Two of the buildings were designated as the experimental schools and teachers worked directly with the researcher as an industrial partner. The third school served as a control with no organized industrial partner. An additional school building in a second suburban school district was selected to serve as a comparison school and a second scientist participated as an industrial volunteer. Unlike the researcher, this scientist had no formal training in science education. Each phase of the study included instruments piloted and reviewed by experienced elementary teachers for appropriateness or by objective experts in the field of education. A student attitude survey and selected tasks from the Inventory of Piagetian Developmental Tasks were administered to all students involved in the study. Empirical data collected through videotaped analysis using the validated Modified-Revised Vickery Science Teacher Behavior Inventory led to the development of a pattern of the most frequently used behaviors during elementary science instruction. A profile of each participating teacher was developed through the use of a validated attitude survey, notes taken during classroom interactions and from information collected during ethnographic interviews. A major conclusion drawn from this study is that neither type

  2. Induced immune response of Escherichia coli BL21 expressing recombinant MSP1a and MSP1b proteins of Anaplasma marginale

    Directory of Open Access Journals (Sweden)

    Katia Tamekuni


    Full Text Available This work aims to evaluate the potential of immunization with E. coli BL21 expressing the recombinant rMSP1a and rMSP1b proteins of Anaplasma marginale. E. coli BL21 was transformed with recombinant plasmids pET102/msp1α and pET101/msp1β, and rMSP1a and rMSP1b were expressed after induction by IPTG. BALB/c mice were vaccinated with formolized BL21/rMSP1a and BL21/rMSP1b, and the production in mice sera of whole IgG was determined by ELISA. The mice immunized with BL21/rMSP1a showed a better humoral response for whole IgG when compared to the mice immunized with BL21/rMSP1b; these mice exhibited a small response after the second vaccination. Sera of mice immunized with BL21/rMSP1a reacted via western blot with BL21 and rMSP1a, with molecular masses varying from 70 to 105 kDa. Sera of mice immunized with BL21/rMSP1b reacted with BL21 and rMSP1b with a molecular mass of 100 kDa. These results demonstrate that BL21 containing rMSP1a and rMSP1b in the outer membrane were able to produce an immune response in mice, reinforcing its use in vaccine models against bovine anaplasmosis.Esse trabalho avaliou o potencial de imunização de Escherichia coli BL21 expressando as proteínas recombinantes rMSP1a e rMSP1b de Anaplasma marginale. A E. coli BL21 foi transformada com os plasmídios recombinantes pET102/msp1α e pET101/msp1β e as proteínas rMSP1a e rMSP1b foram expressas após indução com IPTG. Camundongos BALB/c foram vacinados com BL21/rMSP1a e BL21/rMSP1b formolisadas, e a produção de IgG total foi determinada pelo teste de ELISA nos soros dos camundongos imunizados. Os camundongos imunizados com a BL21/rMSP1a mostraram uma melhor resposta humoral para IgG total, comparada à resposta apresentada pelos camundongos imunizados com BL21/rMSP1b; estes camundongos exibiram uma menor resposta após a segunda vacinação. Soros de camundongos imunizados BL21/rMSP1a reagiram pelo western blot com BL21 e rMSP1a, com massa molecular variando de 70 a

  3. Involving stakeholders in the commissioning and implementation of fishery science projects: experiences from the U.K. Fisheries Science Partnership. (United States)

    Armstrong, M J; Payne, A I L; Deas, B; Catchpole, T L


    Following from similar initiatives worldwide, the U.K.'s Fisheries Science Partnership (FSP) was established in 2003 to provide the fishing industry with opportunities to propose and participate in scientific studies in collaboration with fishery scientists. Key concepts were that most of the available funding would support industry participation, that industry, not scientists, would come up with the ideas for projects, and that commercial fishing vessels and fishing methods would be used to address specific concerns of the fishing industry in a scientifically controlled manner. Nearly 100 projects had been commissioned by March 2012, covering annual time-series surveys of stocks subject to traditional assessment, and ad hoc projects on, e.g. gear selectivity, discard survival, tagging and migration and fishery development. The extent to which the results of the projects have been used by stakeholders, fishery scientists and fishery managers at a national and E.U. level is evaluated, along with the degree of industry interest and involvement, and reasons are identified for successes or failures in the uptake of the results into management and policy. Finally, the question is posed whether the programme has been successful in improving the engagement of the fishing community in the science-management process and in fostering communication and greater trust between fishers, scientists and managers. © 2013 Crown Copyright. © 2013 The Fisheries Society of the British Isles.

  4. GLOBE Observer and the Association of Science & Technology Centers: Leveraging Citizen Science and Partnerships for an International Science Experiment to Build Climate Literacy (United States)

    Riebeek Kohl, H.; Chambers, L. H.; Murphy, T.


    For more that 20 years, the Global Learning and Observations to Benefit the Environment (GLOBE) Program has sought to increase environment literacy in students by involving them in the process of data collection and scientific research. In 2016, the program expanded to accept observations from citizen scientists of all ages through a relatively simple app. Called GLOBE Observer, the new program aims to help participants feel connected to a global community focused on advancing the scientific understanding of Earth system science while building climate literacy among participants and increasing valuable environmental data points to expand both student and scientific research. In October 2016, GLOBE Observer partnered with the Association of Science & Technology Centers (ASTC) in an international science experiment in which museums and patrons around the world collected cloud observations through GLOBE Observer to create a global cloud map in support of NASA satellite science. The experiment was an element of the International Science Center and Science Museum Day, an event planned in partnership with UNESCO and ASTC. Museums and science centers provided the climate context for the observations, while GLOBE Observer offered a uniform experience and a digital platform to build a connected global community. This talk will introduce GLOBE Observer and will present the results of the experiment, including evaluation feedback on gains in climate literacy through the event.

  5. The Upper San Pedro Partnership: A Case Study of Successful Strategies to Connect Science to Societal Needs (United States)

    Goodrich, D. C.; Richter, H.; Varady, R.; Browning-Aiken, A.; Shuttleworth, J.


    The Upper San Pedro Partnership (USPP) ( has been in existence since 1998. Its purpose is to coordinate and cooperate in the implementation of comprehensive policies and projects to meet the long-term water needs of residents within the U.S. side of the basin and of the San Pedro Riparian National Conservation Area. The Partnership consists of 21 local, state, and Federal agencies, NGO's and a private water company. In 2004 it was recognized by Congress in Section 321 of Public Law 108-136 and required to make annual reports to Congress on its progress in bringing the basin water budget into balance by 2011. The Partnership is dedicated to science-based decision making. This presentation will provide an overview of the evolution of natural resources research in the binational (U.S.-Mexico) San Pedro Basin into a mature example of integrated science and decision making embodied in the USPP. It will discuss the transition through science and research for understanding; to science for addressing a need; to integrated policy development and science. At each stage the research conducted becomes more interdisciplinary, first across abiotic disciplines (hydrology, remote sensing, atmospheric science), then a merging of abiotic and biotic disciplines (adding ecology and plant physiology), and finally a further merging with the social sciences and policy and decision making for resource management. Federal, university, and NSF SAHRA Science and Technology Center research has been planned and conducted directly with the USPP. Because of the success the San Pedro has been designated as an operational HELP (Hydrology for the Environment, Life, and Policy) demonstration basin—the most advanced category. Lessons learned from this experience will be reviewed with the intent providing guidance to ensure that hydrologic and watershed research is socially and scientifically relevant and will directly address the needs of policy makers and resource

  6. Northern Eurasia Earth Science Partnership Initiative in the past 12 months: An Update (United States)

    Groisman, Pavel; Lowford, Richard


    Eight years ago Northern Eurasia Earth Science Partnership Initiative (NEESPI) was launched with the release of its Science Plan ( Gradually, the Initiative was joined by numerous international projects launched in EU, Russia, the United States, Canada, Japan, and China. Throughout its duration, NEESPI served and is serving as an umbrella for more than 155 individual international research projects. Currently, the total number of the ongoing NEESPI projects (as on January 2013) is 48 and has changed but slightly compared to its peak (87 in 2008). The past 12 months (from the previous EGU Assembly) were extremely productive in the NEESPI outreach. We organized three Open Science Sessions at the three major Geoscience Unions/Assembly Meetings (JpGU, AGU, and this EGU Session) and three International NEESPI Workshops. The programs of two of these Workshops (in Yoshkar Ola and Irkutsk, Russia) included Summer Schools for early career scientists. More than 150 peer-reviewed papers, books, and/or book chapters were published in 2012 or are in press (this list was still incomplete at the time of preparation of this abstract). In particular, a suite of 25 peer-reviewed NEESPI articles was published in the Forth Special NEESPI Issue of "Environmental Research Letters" (ERL) (this is the third ERL Issue). In December 2012, the next Special ERL NEESPI Issue was launched Northern Eurasia is a large study domain. Therefore, it was decided to describe the latest findings related to its environmental changes in several regional monographs in English. Three books on Environmental Changes in the NEESPI domain were published by the University of Helsinki (Groisman et al. 2012), "Akademperiodyka" (Groisman and Lyalko 2012), and Springer Publishing House (Groisman and Gutman 2013) being devoted to the high latitudes of Eurasia, to Eastern Europe, and to Siberia

  7. Providing Middle School Students With Science Research Experiences Through Community Partnerships (United States)

    Rodriguez, D.


    Science research courses have been around for years at the university and high school level. As inquiry based learning has become more and more a part of the science teacher's vocabulary, many of these courses have adopted an inquiry model for studying science. Learners of all ages benefit from learning through the natural process of inquiry. I participated in the CIRES Earthworks program for science teachers (Colorado University) in the summer of 2007 and experienced, first hand, the value of inquiry learning. With the support and vision of my school administration, and with the support and commitment of community partners, I have developed a Middle School Science Research Program that is transforming how science is taught to students in my community. Swift Creek Middle School is located in Tallahassee, Florida. There are approximately 1000 students in this suburban public school. Students at Swift Creek are required to take one science class each year through 8th grade. As more emphasis is placed on learning a large number of scientific facts and information, in order to prepare students for yearly, standardized tests, there is a concern that less emphasis may be placed on the process and nature of science. The program I developed draws from the inquiry model followed at the CIRES Earthworks program, utilizes valuable community partnerships, and plays an important role in meeting that need. There are three major components to this Middle School Research Program, and the Center for Integrated Research and Learning (CIRL) at the National High Magnetic Field Lab (NHMFL) at Florida State University is playing an important role in all three. First, each student will develop their own research question and design experiments to answer the question. Scientists from the NHMFL are serving as mentors, or "buddy scientists," to my students as they work through the process of inquiry. Scientists from the CIRES - Earthworks program, Florida State University, and other

  8. Leveraging Research Partnerships to Co-Produce Actionable Science and Build Institutional Capacity (United States)

    Fleming, P.; Chinn, A.; Rufo Hill, J.; Edgerly, J.; Garcia, E.


    Seattle Public Utilities (SPU) provides high quality drinking water to 1.4 million people in the greater Seattle area and storm, wastewater and solid waste services to the City of Seattle. SPU's engagement on climate change has evolved significantly over the past 20 years. What began in 1997 as an inquiry into how El Nino may affect water supply has evolved into a broad based ongoing exploration that includes extensive in-house knowledge, capacity and expertise. This presentation will describe SPU's evolution from a funder and consumer of climate research to an active contributor to the development of applied research products, highlighted SPU's changing role in three climate impacts assessment studies. It will describe how SPU has leveraged these studies and partnerships to enhance its knowledge base, build its internal institutional capacity and produce actionable science that it is helping to foster incorporation of climate change into various aspects of utility planning and decision making. It will describe the PUMA Project and how the results from that research effort are being factored into SPU's state mandated Water System Plan.

  9. UCSF partnership to enrich science teaching for sixth graders in San Francisco's schools. (United States)

    Doyle, H J


    Increasing the diversity of students entering the health professions is a challenging goal for medical schools. One approach to this goal is to share the enthusiasm and energy of medical students with younger students, who may pursue medical education in the future. The MedTeach program, established in 1989 and coordinated by the Science & Health Education Partnership of the University of California, San Francisco (UCSF), does so by partnering volunteer medical students from UCSF with sixth-grade classes studying the human body. In 1997-98, around 350 sixth-graders in the San Francisco Schools benefitted from the program. Each team of medical student's visits its class ten to 12 times a year to present engaging, hands-on lessons on body systems and health. The medical students are also role models for the middle-school students. In addition, the diverse student population of San Francisco public schools provides a rich environment for the medical students to improve their communication and teaching skills.

  10. The National Aeronautics and Space Administration's Earth Science Applications Program: Exploring Partnerships to Enhance Decision Making in Public Health Practice (United States)

    Vann, Timi S.; Venezia, Robert A.


    The National Aeronautics and Space Administration (NASA), Earth Science Enterprise is engaged in applications of NASA Earth science and remote sensing technologies for public health. Efforts are focused on establishing partnerships with those agencies and organizations that have responsibility for protecting the Nation's Health. The program's goal is the integration of NASA's advanced data and technology for enhanced decision support in the areas of disease surveillance and environmental health. A focused applications program, based on understanding partner issues and requirements, has the potential to significantly contribute to more informed decision making in public health practice. This paper intends to provide background information on NASA's investment in public health and is a call for partnership with the larger practice community.

  11. Ten Years of Northern Eurasia Earth Science Partnership Initiative (NEESPI): Results and Future Plans (United States)

    Groisman, P. Y.; Gutman, G.; Gulev, S.; Maksyutov, S. S.


    During recent decades, Northern Eurasia was affected by unprecedented climate and environmental changes. Several droughts and heat waves alternated with hazardous extreme precipitation and flood events. Permafrost thaw, retreating Arctic sea ice, increasing areas of forest fire, and dramatic regional warming buffeted this region, tossing northern Eurasia from one extreme condition to the next. The region stores nearly half of the Earth's terrestrial carbon in permafrost, wetlands, and forested land, so ecosystem changes that release stored carbon could profoundly affect the world's climate. Furthermore, changes to climate and to hydrological and biogeochemical cycles are starting to affect daily life. For example, infrastructure is collapsing as permafrost thaws, severe winter storms increasingly bring businesses to a halt, and a growing water deficit is beginning to strain agricultural production and forestry. To pool resources and facilitate research, the Northern Eurasia Earth Science Partnership Initiative (NEESPI, was launched in 2004. With its multidisciplinary focus, the internationally funded NEESPI (more than165 individual international projects during the past decade) has challenged participants to research climate-ecosystem interactions, societal impacts from extreme events in Northern Eurasia, and the feedbacks of these interactions and impacts to the global Earth system. Among the numerous Institutional and private sponsors from the United States, European Union, Russia, China, and Japan, the cornerstone support for the NEESPI studies was provided by the NASA Land Cover and Land Use Change Program and the Russian Academy of Sciences. At this presentation we shall overview the environmental studies conducted by the NEESPI community, brief the audience about the main achievements of the NEESPI researchers, and lay down the plans for the future studies. At the side event of the Meeting, we are going to initiate preparation of the book

  12. Development of a Pulse Oximeter Using MSP430 Microcontroller


    Gayathri.R; Hepsiba.D


    In this paper,we propose and demonstrate the design of a Pulse Oximeter using MSP430FG439 Microcontroller.The Oxygen Saturation and Heart Rate are the two important key parameters for health monitoring of a patients.The proposed system consists of spo₂ Sensor,MSP430FG439 Pulse Oximeter board With LCD Display,PC.The oxygen saturation is calculated by measuring the ratio between the intensities of two different lights.The heart rate is calculated by measuring the elapsed time between the peaks ...

  13. Where science meets technology Cern and Oracel - a long-standing partnership

    CERN Multimedia

    Garvey, Kelsey


    "Even though the partnership between Cern and Oracle has lasted 27 years, the partnership between Cern openlab and Oarcle only began in 2003. This collaboration has allowed both companies to team up at the intersection of business and technology and to excel in their respective endeavours" (1 page)

  14. The North Cascadia Adaptation Partnership: a science-management collaboration for responding to climate change (United States)

    Crystal L. Raymond; David L. Peterson; Regina M. Rochefort


    The U.S. Forest Service (USFS) and National Park Service (NPS) have highlighted climate change as an agency priority and issued direction to administrative units for responding to climate change. In response, the USFS and NPS initiated the North Cascadia Adaptation Partnership (NCAP) in 2010. The goals of the NCAP were to build an inclusive partnership, increase...

  15. From the Northern Eurasia Earth Science Partnership Initiative to the Northern Eurasia Future Initiative (United States)

    Streletskiy, D. A.; Groisman, P. Y.; Shugart, H. H., Jr.; Gulev, S.; Maksyutov, S. S.; Qi, J.


    Since 2004, the Northern Eurasia Earth Science Partnership Initiative (NEESPI) - an interdisciplinary program of internationally-supported Earth systems and science research - has addressed large-scale and long-term manifestations of climate and environmental changes over Northern Eurasia and their impact on the Global Earth system. With 40 books and more than 1500 peer-reviewed journal publications to its credit, NEESPI's output can now be used to directly support decision-making for societal needs. Specifically, it was decided to shift gradually the foci of regional studies in Northern Eurasia towards applications with the following major Science Question: "What dynamic and interactive change(s) will affect societal well-being, activities, and health, and what might be the mitigation and adaptation strategies that could support sustainable development and decision-making activities in Northern Eurasia?" To answer this question requires a stronger socio-economic component in the ongoing and future regional studies focused on sustainable societal development under changing climatic and environmental conditions. The NEESPI Research Team has reorganized itself into "Northern Eurasia Future Initiative" (NEFI) and developed a new Science Plan released in June 2016. The Plan underwent a 6-month-long public review and was finalized at the end of 2016. Its description was thereafter split between two review papers: Groisman et al. (2017) and Monier et al. (2017). The first paper describes the Plan rationale and a new set of topical questions. The second paper describes a major modeling approach that will be employed in addressing the "what to do" questions of the NEFI Research (cf., presentation by Monier et al. at this Session). In the current presentation, we outline the new NEFI research foci and present latest NEFI findings including international projects in the Eurasian Arctic, boreal zone, and the Dry Land Belt of Northern Eurasia (cf., also presentations at sister

  16. `INCLUDING' Partnerships to Build Authentic Research Into K-12 Science Education (United States)

    Turrin, M.; Lev, E.; Newton, R.; Xu, C.


    Opportunities for authentic research experiences have been shown effective for recruiting and retaining students in STEM fields. Meaningful research experiences entail significant time in project design, modeling ethical practice, providing training, instruction, and ongoing guidance. We propose that in order to be sustainable, a new instructional paradigm is needed, one that shifts from being top-weighted in instruction to a distributed weight model. This model relies on partnerships where everyone has buy-in and reaps rewards, establishing broadened networks for support, and adjusting the mentoring model. We use our successful Secondary School Field Research Program as a model for this new paradigm. For over a decade this program has provided authentic geoscience field research for an expanding group of predominantly inner city high school youth from communities underrepresented in the sciences. The program has shifted the balance with returning participants now serving as undergraduate mentors for the high school student `researchers', providing much of the ongoing training, instruction, guidance and feedback needed. But in order to be sustainable and impactful we need to broaden our base. A recent NSF-INCLUDES pilot project has allowed us to expand this model, linking schools, informal education non-profits, other academic institutions, community partners and private funding agencies into geographically organized `clusters'. Starting with a tiered mentoring model with scientists as consultants, teachers as team members, undergraduates as team leaders and high school students as researchers, each cluster will customize its program to reflect the needs and strengths of the team. To be successful each organization must identify how the program fits their organizational goals, the resources they can contribute and what they need back. Widening the partnership base spreads institutional commitments for research scientists, research locations and lab space

  17. Helix Nebula - the Science Cloud: a public-private partnership to build a multidisciplinary cloud platform for data intensive science (United States)

    Jones, Bob; Casu, Francesco


    The feasibility of using commercial cloud services for scientific research is of great interest to research organisations such as CERN, ESA and EMBL, to the suppliers of cloud-based services and to the national and European funding agencies. Through the Helix Nebula - the Science Cloud [1] initiative and with the support of the European Commission, these stakeholders are driving a two year pilot-phase during which procurement processes and governance issues for a framework of public/private partnership will be appraised. Three initial flagship use cases from high energy physics, molecular biology and earth-observation are being used to validate the approach, enable a cost-benefit analysis to be undertaken and prepare the next stage of the Science Cloud Strategic Plan [2] to be developed and approved. The power of Helix Nebula lies in a shared set of services for initially 3 very different sciences each supporting a global community and thus building a common e-Science platform. Of particular relevance is the ESA sponsored flagship application SuperSites Exploitation Platform (SSEP [3]) that offers the global geo-hazard community a common platform for the correlation and processing of observation data for supersites monitoring. The US-NSF Earth Cube [4] and Ocean Observatory Initiative [5] (OOI) are taking a similar approach for data intensive science. The work of Helix Nebula and its recent architecture model [6] has shown that is it technically feasible to allow publicly funded infrastructures, such as EGI [7] and GEANT [8], to interoperate with commercial cloud services. Such hybrid systems are in the interest of the existing users of publicly funded infrastructures and funding agencies because they will provide "freedom of choice" over the type of computing resources to be consumed and the manner in which they can be obtained. But to offer such freedom-of choice across a spectrum of suppliers, various issues such as intellectual property, legal responsibility

  18. Impact of a Student-Teacher-Scientist Partnership on Students' and Teachers' Content Knowledge, Attitudes toward Science, and Pedagogical Practices (United States)

    Houseal, Ana K.; Abd-El-Khalick, Fouad; Destefano, Lizanne


    Engaging K-12 students in science-based inquiry is at the center of current science education reform efforts. Inquiry can best be taught through experiential, authentic science experiences, such as those provided by Student-Teacher-Scientist Partnerships (STSPs). However, very little is known about the impact of STSPs on teachers' and…

  19. Meaningful Engagement of Organizational and Agency Partnerships to Enhance Diversity within the Earth System Science Community: A Case Study (United States)

    Pyrtle, A. J.; Whitney, V. W.; Powell, J. M.; Bailey, K. L.


    The Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science Initiative (MS PHD'S) was established by and for underrepresented minorities to facilitate increased and sustained participation in Earth system science community. The MS PHD'S launched its pilot program in 2003 with twenty professional organizations, agencies and institutions as partners. Each year partnership alliances have grown. In the second year or programming, thirty-one partnering agencies/institutions supported involvement of MS PHD'S student participants and for 2005-2006, representatives from forty-five agencies and institutions have provided similar support and exposure to the third cohort of student participants. Nineteen scientists served as meeting mentors during the MS PHD'S pilot program in 2003. By the following year, twenty-two additional scientists partnered with MS PHD'S mentees. During 2005-2006, twenty-one new scientists served as program mentors. Thus far, the MS PHD'S program has successfully engaged sixty-two minority and non-minority scientists as mentors to MS PHD'S student participants. AGU, AMS, ASLO, ESA, TOS, NAS OSB and JOI continue to serve as MS PHD'S Society Partners and hosts for MS PHD'S student activities in conjunction with their meetings. Each of the five professional society partners provided assistance in identifying mentors, provided complimentary memberships and meeting registrations for MS PHD'S student participants. AGU, AMS, ASLO, JOI and TOS have sponsored more than 90 conference registration and travel awards for the purpose of student participants engaging in MS PHD'S Professional Development Program Phase 2 activities at their international meetings. How did MS PHD'S establish meaningful engagement of organizational and agency partnerships to enhance diversity within the Earth system science community? This case study reveals replicable processes and constructs to enhance the quality of meaningful collaboration and engagement

  20. University/Science Center Collaborations (A Science Center Perspective): Developing an Infrastructure of Partnerships with Science Centers to Support the Engagement of Scientists and Engineers in Education and Outreach for Broad Impact (United States)

    Marshall, Eric


    Science centers, professional associations, corporations and university research centers share the same mission of education and outreach, yet come from ``different worlds.'' This gap may be bridged by working together to leverage unique strengths in partnership. Front-end evaluation results for the development of new resources to support these (mostly volunteer-based) partnerships elucidate the factors which lead to a successful relationship. Maintaining a science museum-scientific community partnership requires that all partners devote adequate resources (time, money, etc.). In general, scientists/engineers and science museum professionals often approach relationships with different assumptions and expectations. The culture of science centers is distinctly different from the culture of science. Scientists/engineers prefer to select how they will ultimately share their expertise from an array of choices. Successful partnerships stem from clearly defined roles and responsibilities. Scientists/engineers are somewhat resistant to the idea of traditional, formal training. Instead of developing new expertise, many prefer to offer their existing strengths and expertise. Maintaining a healthy relationship requires the routine recognition of the contributions of scientists/engineers. As professional societies, university research centers and corporations increasingly engage in education and outreach, a need for a supportive infrastructure becomes evident. Work of (Volunteers TryScience), the MRS NISE Net (Nanoscale Informal Science Education Network) subcommittee, NRCEN (NSF Research Center Education Network), the IBM On Demand Community, and IEEE Educational Activities exemplify some of the pieces of this evolving infrastructure.

  1. The influence of science funding agencies in support of effective decision-maker scientist partnerships (United States)

    Arnott, J. C.; Lemos, M. C.


    A wealth of evidence supports the idea that collaboration between scientists and decision-makers is an influential factor in generating actionable knowledge. Nevertheless, persistent obstacles across the research-policy-practice interface limit the amount of engagement that may be necessary to satisfy demands for information to support decisions. Funding agencies have been identified as one possible driver of change, but few multi-year studies have been conducted to trace the influence of program designs on research practices or other outcomes. To fill this gap, we examine a body of applied science projects (n=120) funded through NOAA's National Estuarine Research Reserve System from 1998-2014. Periodic innovation in the structure of this funding program, including requirements for end user engagement and the inclusion of collaboration specialists, offers a natural experiment from which to test hypotheses about the how funding program design influences research practice, utilization, and broader impacts. Using content analysis of project reports and interviews of project team members, end users, and program managers (n=40), we produce a data that can be analyzed through both statistical and qualitative methods. We find that funder mandates significantly influence the intensity of interaction between researchers and practitioners as well as affect long-term change in research cultures. When interaction intensifies, corresponding gains appear in the readiness of research to support decision-making and the readiness of user groups to incorporate findings into their work. While collaborative methods transform research practice and positively influence the applied contexts in which partnerships occur, it remains less clear whether this actually increases the direct use of scientific to inform decisions. For example, collaboration may lead to outcomes other than new knowledge or knowledge application, yielding many positive outcomes that are distinct from knowledge use

  2. Initiating New Science Partnerships in Rural Education (INSPIRE): Enhancing Scientific Communication by Bringing STEM Research into the Classroom (United States)

    Pierce, D.; Radencic, S.; Funderburk, W. K.; Walker, R. M.; Jackson, B. S.; Dawkins, K. S.; Schmitz, D.; Bruce, L. M.; McNeal, K.


    INSPIRE, a five-year partnership between Mississippi State University and three local school districts, is designed to strengthen the communication skills of graduate Fellows in geosciences, physics, astronomy, chemistry, and engineering as they incorporate their research into inquiry-based lessons in 7th - 12th grade science and math classrooms. All lesson plans designed and taught by the graduate Fellows must include one or more connections to their research, and these connections must be demonstrated to the students during the lessons. International research partnerships with Australia, the Bahamas, England, and Poland provide valuable opportunities for graduate Fellows to conduct field work abroad and allow our partner teachers to have authentic research experiences that they can bring back to their classrooms. Program effectiveness has been examined using pre- and post-year attitudinal surveys, formal lesson plan documents, Fellow and teacher journals, focus group meetings with a project evaluator, and direct observation of Fellow-led classroom activities. Analyses of data gathered during the past four years of the partnership will be presented that examine the diversity in approaches taken by Fellows to communicate big ideas, changes in the ability of Fellows to find connections between their research and classroom lessons while keeping them aligned with state and national standards, and the quality of the mentorship provided to the Fellows by our partner teachers. INSPIRE is funded by the Graduate K-12 (GK-12) STEM Fellowship Program of the National Science Foundation (Award No. DGE-0947419).

  3. Sustaining International Partnerships: The European Master of Science Program In Occupational Therapy: A Case Study

    DEFF Research Database (Denmark)

    Ilott, Irene; Kottorp, Anders; la Cour, Karen


    Abstract International partnerships are a mechanism for supporting the academic development of occupational therapy and promoting cultural competence. This case study describes the factors that have helped to sustain a post-qualifying programme implemented by five higher education institutions...... comprises students from an average of eight countries to optimize inter-cultural dialogue. Four factors support sustainability. These are 1) supportive professional European networks; 2) timeliness and alignment with European higher education policy; 3) partnership structures and processes that emphasize...

  4. An overview of the Southern Nevada Agency Partnership science and research synthesis: Chapter 1 in The Southern Nevada Agency Partnership science and research synthesis: science to support land management in southern Nevada (United States)

    Chambers, Jeanne C.; Brooks, Matthew L.; Turner, Kent; Raish, Carol B.; Ostoja, Steven M.


    Maintaining and restoring the diverse ecosystems and resources that occur in southern Nevada in the face of rapid socio-economic and ecological change presents numerous challenged to Federal land managers. Rapid population growth since the 1980s, the land uses associated with that growth, and the interactions of those uses with the generally dry and highly variable climate result in numerous stresses to ecosystems, species, and cultural resource. In addition, climate models predict that the rate of temperature increase and, thus, changes in ecological processes, will be highest for ecosystems like the Mojave Desert. The Southern Nevada Agency Partnership (SNAP; was established in 1999 to address common issues pertaining to public lands in southern Nevada. Partners include the Bureau of Land Management, National Park Service, U.S. Fish and Wildlife Service, and USDA Forest Service and they work with each other, the local community, and other partners. SNAP agencies manage more than seven million acres of public lands in southern Nevada (95% of the land area). Federal land includes two national recreation areas, two national conservation area, four national wildlife refuges, 18 congressionally designated wilderness areas, five wilderness study areas, and 22 areas of critical environmental concern. The partnership's activities are mainly centered in Southern Nevada's Clark County (fig. 1.1), but lands managed by SNAP partner agencies also include portions of Lake Mead National Recreation Area in Mohave County, Arizona, U.S. Fish and Wildlife Service, and USDA Forest Service-managed lands in Lincoln and Nye Counties, Nevada, and all lands and activities managed by the Southern Nevada District Office of the Bureau of Land Management. These lands encompass nine distinct ecosystem types (fig. 1.2), support multiple species of management concern an 17 listed species, and are rich in cultural and historic resource. This introductory executive summary

  5. TRUST: A Successful Formal-Informal Teacher Education Partnership Designed to Improve and Promote Urban Earth Science Education (United States)

    Sloan, H.; Drantch, K.; Steenhuis, J.


    We present an NSF-funded collaborative formal-informal partnership for urban Earth science teacher preparation and professional development. This model brings together The American Museum of Natural History (AMNH) and Brooklyn and Lehman College of the City University of New York (CUNY) to address science-impoverished classrooms that lack highly qualified teachers by focusing on Earth science teacher certification. Project design was based on identified needs in the local communities and schools, careful analysis of content knowledge mastery required for Earth science teacher certification, and existing impediments to certification. The problem-based approach required partners to push policy envelopes and to invent new ways of articulating content and pedagogy at both intra- and inter-institutional levels. One key element of the project is involvement of the local board of education, teachers, and administrators in initial design and ongoing assessment. Project components include formal Earth systems science courses, a summer institute primarily led and delivered by AMNH scientists through an informal series of lectures coupled to workshops led by AMNH educators, a mechanism for assigning course credit for informal experiences, development of new teaching approaches that include teacher action plans and an external program of evaluation. The principal research strand of this project focuses on the resulting model for formal-informal teacher education partnership, the project's impact on participating teachers, policy issues surrounding the model and the changes required for its development and implementation, and its potential for Earth science education reform. As the grant funded portion of the project draws to a close we begin to analyze data collected over the past 3 years. Third-year findings of the project's external evaluation indicate that the problem-based approach has been highly successful, particularly its impact on participating teachers. In addition

  6. Genetic diversity of the msp-1, msp-2, and glurp genes of Plasmodium falciparum isolates along the Thai-Myanmar borders. (United States)

    Congpuong, Kanungnit; Sukaram, Rungniran; Prompan, Yuparat; Dornae, Aibteesam


    To study the genetic diversity at the msp-1, msp-2, and glurp genes of Plasmodium falciparum (P. falciparum) isolates from 3 endemic areas in Thailand: Tak, Kanchanaburi and Ranong provinces. A total of 144 P. falciparum isolates collected prior to treatment during January, 2012 to June, 2013 were genotyped. DNA was extracted; allele frequency and diversity of msp-1, msp-2, and glurp genes were investigated by nested polymerase chain reaction. P. falciparum isolates in this study had high rate of multiple genotypes infection (96.5%) with an overall mean multiplicity of infection of 3.21. The distribution of allelic families of msp-1 was significantly different among isolates from Tak, Kanchanaburi, and Ranong but not for the msp-2. K1 and MAD20 were the predominant allelic families at the msp-1 gene, whereas alleles belonging to 3D7 were more frequent at the msp-2 gene. The glurp gene had the least diverse alleles. Population structure of P. falciparum isolates from Tak and Ranong was quite similar as revealed by the presence of similar proportions of MAD20 and K1 alleles at msp-1 loci, 3D7 and FC27 alleles at msp-2 loci as well as comparable mean MOI. Isolates from Kanchanaburi had different structures; the most prevalent alleles were K1 and RO33. The present study shows that P. falciparum isolates from Tak and Ranong provinces had similar allelic pattern of msp-1 and msp-2 and diversity but different from Kanchanaburi isolates. These allelic variant profiles are valuable baseline data for future epidemiological study of malaria transmission and for continued monitoring of polymorphisms associated with antimalarial drug resistance in these areas.

  7. How partnership accelerates Open Science: High Energy Physics and INSPIRE, a case study of a complex repository ecosystem

    CERN Document Server

    AUTHOR|(CDS)2079501; Hecker, Bernard Louis; Holtkamp, Annette; Mele, Salvatore; O'Connell, Heath; Sachs, Kirsten; Simko, Tibor; Schwander, Thorsten


    Public calls, agency mandates and scientist demand for Open Science are by now a reality with different nuances across diverse research communities. A complex “ecosystem” of services and tools, mostly communityDdriven, will underpin this revolution in science. Repositories stand to accelerate this process, as “openness” evolves beyond text, in lockstep with scholarly communication. We present a case study of a global discipline, HighDEnergy Physics (HEP), where most of these transitions have already taken place in a “social laboratory” of multiple global information services interlinked in a complex, but successful, ecosystem at the service of scientists. We discuss our firstDhand experience, at a technical and organizational level, of leveraging partnership across repositories and with the user community in support of Open Science, along threads relevant to the OR2013 community.

  8. Evaluation results of the GlobalWatershed GK-12 Fellowship Program - a model for increased science literacy and partnership (United States)

    Mayer, A. S.; Vye, E.


    The Michigan Tech GlobalWatershed GK-12 Fellowship program bridges the gap between K-12 learning institutions and the scientific community with a focus on watershed research. Michigan Tech graduate students (fellows) work in tandem with teachers on the development of relevant hands-on, inquiry based lesson plans and activities based on their doctoral research projects in watershed science. By connecting students and teachers to state of the art academic research in watershed science, teachers are afforded a meaningful way in which to embed scientific research as a component of K-12 curricula, while mentoring fellows on the most pertinent and essential topics for lesson plan development. Fellows fulfill their vital responsibility of communicating their academic research to a broader public while fostering improved teaching and communication skills. A goal of the project is to increase science literacy among students so they may understand, communicate and participate in decisions made at local, regional, and global levels. The project largely works with schools located in Michigan's western Upper Peninsula but also partners with K-12 systems in Sonora, Mexico. While focusing on local and regional issues, the international element of the project helps expand student, teacher, and fellow worldviews and global awareness of watershed issues and creates meaningful partnerships. Lesson plans are available online and teacher workshops are held regularly to disseminate the wealth of information and resources available to the broader public. Evaluation results indicate that fellows' skill and confidence in their ability to communicate science increased as a results of their participation of the program, as well as their desire to communicate science in their future careers. Teachers' confidence in their capacity to present watershed science to their students increased, along with their understanding of how scientific research contributes to understanding of water

  9. A community translational research pilot grants program to facilitate community--academic partnerships: lessons from Colorado's clinical translational science awards. (United States)

    Main, Deborah S; Felzien, Maret C; Magid, David J; Calonge, B Ned; O'Brien, Ruth A; Kempe, Allison; Nearing, Kathryn


    National growth in translational research has increased the need for practical tools to improve how academic institutions engage communities in research. One used by the Colorado Clinical and Translational Sciences Institute (CCTSI) to target investments in community-based translational research on health disparities is a Community Engagement (CE) Pilot Grants program. Innovative in design, the program accepts proposals from either community or academic applicants, requires that at least half of requested grant funds go to the community partner, and offers two funding tracks: One to develop new community-academic partnerships (up to $10,000), the other to strengthen existing partnerships through community translational research projects (up to $30,000). We have seen early success in both traditional and capacity building metrics: the initial investment of $272,742 in our first cycle led to over $2.8 million dollars in additional grant funding, with grantees reporting strengthening capacity of their community- academic partnerships and the rigor and relevance of their research.

  10. Fidelity of test development process within a national science grant (United States)

    Brumfield, Teresa E.

    In 2002, a math-science partnership (MSP) program was initiated by a national science grant. The purpose of the MSP program was to promote the development, implementation, and sustainability of promising partnerships among institutions of higher education, K-12 schools and school systems, as well as other important stakeholders. One of the funded projects included a teacher-scientist collaborative that instituted a professional development system to prepare teachers to use inquiry-based instructional modules. The MSP program mandated evaluations of its funded projects. One of the teacher-scientist collaborative project's outcomes specifically focused on teacher and student science content and process skills. In order to provide annual evidence of progress and to measure the impact of the project's efforts, and because no appropriate science tests were available to measure improvements in content knowledge of participating teachers and their students, the project contracted for the development of science tests. This dissertation focused on the process of test development within an evaluation and examined planned (i.e., expected) and actual (i.e., observed) test development, specifically concentrating on the factors that affected the actual test development process. Planned test development was defined as the process of creating tests according to the well-established test development procedures recommended by the AERA/APA/NCME 1999 Standards for Educational and Psychological Testing. Actual test development was defined as the process of creating tests as it actually took place. Because case study provides an in-depth, longitudinal examination of an event (i.e., case) in a naturalistic setting, it was selected as the appropriate methodology to examine the difference between planned and actual test development. The case (or unit of analysis) was the test development task, a task that was bounded by the context in which it occurred---and over which this researcher had

  11. Proceedings of the precollege-university partnerships for science and mathematics education conference

    Energy Technology Data Exchange (ETDEWEB)


    In April of 1992 in Atlanta, Georgia, nearly 50 elementary and secondary educators and about 100 postsecondary educators convened to explore their common interests in the conference on precollege-university partnerships. This report summarizes the remarks and conclusions of speakers, panelists, and of attendees gathered in regional work groups. During the course of the conference, attendees heard from federal agencies and foundations which fund education-related projects and learned of their enthusiastic support of partnerships. In our national need to manage education and training resources wisely, these funding agents see partnership benefits such as renewed excitement for teaching at all levels, effective and technologically up-to-date in-service training, more and better-prepared high school graduates entering colleges, and a general enhancement of understanding among educators at all levels of teaching. As an added benefit, the partnership concept promotes discussion and understanding in an atmosphere of respect, appreciation, and self-esteem. Several hours of the conference were devoted to panels addressing five questions important to education coalitions. The panelists represented a wide variety of teaching levels, geographic locations, educational experiences, and ethnic groups.

  12. The InterCon network: a program for education partnerships at the University of Texas-Houston Health Science Center. (United States)

    Castro, G A; Bouldin, P A; Farver, D W; Maugans, L A; Sanders, L C; Booker, J


    The University of Texas-Houston Health Science Center (UT-Houston) has created programs and activities to address the state's pressing needs in minority education. Through InterCon, a network of universities and K-12 schools, UT-Houston works with its partners to identify competitive candidates in the current pool of minority graduates with bachelor's degrees and to help them--along with their non-minority counterparts--progress in their education. Another objective is to expand the pool of minorities underrepresented in medicine who complete high school and go to college. In 1994 UT-Houston and Prairie View A&M University created a collaborative venture to provide new educational opportunities at UT-Houston for Prairie View's predominantly African American students. A three-track summer internship program--a result of that collaboration--has since been expanded to partnerships with other minority and majority universities throughout Texas. In 1998, for example, 108 undergraduate students from these universities (and 40 other universities nationwide) participated in research, professional, and administrative summer internships at UT-Houston. The InterCon network also has partnerships with K-12 schools. UT-Houston works with inner-city, suburban, and rural school districts to develop education models that can be transferred throughout the state. The partnerships deal with helping to teach basic academic skills and computer literacy, improve science-related instruction, meet demands for health promotion materials and information for school-initiated health and wellness programs, and develop distance-learning paradigms. UT-Houston views InterCon as a program helping Texas institutions to engage and adapt to the socioeconomic factors, demographic changes, and technology explosion that currently challenge public education.

  13. Partner-built ecosystem science - The National Ocean Partnership Program as a builder of EBM Tools and Data (United States)

    Hoffman, P. L.; Green, R. E.; Kohanowich, K. M.


    The National Ocean Partnership Program (NOPP) was created in 1997 by federal public law to identify "and carry out partnerships among federal agencies, academia, industry, and other members of the oceanographic scientific community in the areas of data, resources, education, and communications." Since that time, numerous federal agencies have pooled talent, funding, and scientific resources (e.g. ships, aircraft, remote sensors and computing capability) to address pressing ocean science needs which no one entity can manage alone. In this presentation, we will address the ways the National Ocean Policy identifies ecosystem-based management (EBM) as a foundation for providing sound science-based and adaptable management to maintain the health, productivity, and resilience of U.S. ocean, coastal, and Great Lakes ecosystems. Because EBM is an important approach for efficient and effective interagency, multi-jurisdictional, and cross-sectoral marine planning and management, ocean science partnerships such as those provided by NOPP create a pool of regionally-pertinent, nationally-available data from which EBM decision makers can draw to address critical management issues. Specifically, we will provide examples drawn from the last five years of funding to illustrate how the NOPP process works, how it is managed by a federal Interagency Working Group (IWG-OP), and how EBM practitioners can both partner with others through the NOPP and offer guidance on the implementation of projects beneficial to the regional needs of the EBM community. Projects to be discussed have been carried out under the following themes: Arctic Cumulative Impacts: Marine Arctic Ecosystem Study (MARES) - Ecosystem Dynamics and Monitoring of the Beaufort Sea: An Integrated Science Approach. Biodiversity Indicators: Demonstration of a U.S. Marine Biodiversity Observation Network (Marine BON) Long-Term Observations: Coordinated Regional Efforts That Further the U.S. Integrated Ocean Observing System

  14. Dialectical Dividends: Fostering Hybridity of New Pedagogical Practices and Partnerships in Science Education and Outreach (United States)

    Martins Gomes, Diogo; McCauley, Veronica


    Science literacy has become socially and economically very important. European countries stress that science graduates are fundamental for economic growth. Nevertheless, there is a declining student participation in science. In response, there has been a call to change the way science is taught in schools, which focuses on inquiry methods rooted…

  15. Global Learning Communities: A Comparison of Online Domestic and International Science Class Partnerships (United States)

    Kerlin, Steven C.; Carlsen, William S.; Kelly, Gregory J.; Goehring, Elizabeth


    The conception of Global Learning Communities (GLCs) was researched to discover potential benefits of the use of online technologies that facilitated communication and scientific data sharing outside of the normal classroom setting. 1,419 students in 635 student groups began the instructional unit. Students represented the classrooms of 33 teachers from the USA, 6 from Thailand, 7 from Australia, and 4 from Germany. Data from an international environmental education project were analyzed to describe grades 7-9 student scientific writing in domestic US versus international-US classroom online partnerships. The development of an argument analytic and a research model of exploratory data analysis followed by statistical testing were used to discover and highlight different ways students used evidence to support their scientific claims about temperature variation at school sites and deep-sea hydrothermal vents. Findings show modest gains in the use of some evidentiary discourse components by US students in international online class partnerships compared to their US counterparts in domestic US partnerships. The analytic, research model, and online collaborative learning tools may be used in other large-scale studies and learning communities. Results provide insights about the benefits of using online technologies and promote the establishment of GLCs.

  16. In situ observations of meteor smoke particles (MSP during the Geminids 2010: constraints on MSP size, work function and composition

    Directory of Open Access Journals (Sweden)

    M. Rapp


    Full Text Available We present in situ observations of meteoric smoke particles (MSP obtained during three sounding rocket flights in December 2010 in the frame of the final campaign of the Norwegian-German ECOMA project (ECOMA = Existence and Charge state Of meteoric smoke particles in the Middle Atmosphere. The flights were conducted before, at the maximum activity, and after the decline of the Geminids which is one of the major meteor showers over the year. Measurements with the ECOMA particle detector yield both profiles of naturally charged particles (Faraday cup measurement as well as profiles of photoelectrons emitted by the MSPs due to their irradiation by photons of a xenon-flash lamp. The column density of negatively charged MSPs decreased steadily from flight to flight which is in agreement with a corresponding decrease of the sporadic meteor flux recorded during the same period. This implies that the sporadic meteors are a major source of MSPs while the additional influx due to the shower meteors apparently did not play any significant role. Surprisingly, the profiles of photoelectrons are only partly compatible with this observation: while the photoelectron current profiles obtained during the first and third flight of the campaign showed a qualitatively similar behaviour as the MSP charge density data, the profile from the second flight (i.e., at the peak of the Geminids shows much smaller photoelectron currents. This may tentatively be interpreted as a different MSP composition (and, hence, different photoelectric properties during this second flight, but at this stage we are not in a position to conclude that there is a cause and effect relation between the Geminids and this observation. Finally, the ECOMA particle detector used during the first and third flight employed three instead of only one xenon flash lamp where each of the three lamps used for one flight had a different window material resulting in different cut off wavelengths for these

  17. Initiating New Science Partnerships in Rural Education: STEM Graduate Students Bring Current Research into 7th-12th Grade Science Classrooms (United States)

    Radencic, S.; Dawkins, K. S.; Jackson, B. S.; Walker, R. M.; Schmitz, D.; Pierce, D.; Funderburk, W. K.; McNeal, K.


    Initiating New Science Partnerships in Rural Education (INSPIRE), a NSF Graduate K-12 (GK-12) program at Mississippi State University, pairs STEM graduate students with local K-12 teachers to bring new inquiry and technology experiences to the classroom ( The graduate fellows prepare lessons for the students incorporating different facets of their research. The lessons vary in degree of difficulty according to the content covered in the classroom and the grade level of the students. The focus of each lesson is directed toward the individual research of the STEM graduate student using inquiry based designed activities. Scientific instruments that are used in STEM research (e.g. SkyMaster weather stations, GPS, portable SEM, Inclinometer, Soil Moisture Probe, Google Earth, ArcGIS Explorer) are also utilized by K-12 students in the activities developed by the graduate students. Creativity and problem solving skills are sparked by curiosity which leads to the discovery of new information. The graduate students work to enhance their ability to effectively communicate their research to members of society through the creation of research linked classroom activities, enabling the 7-12th grade students to connect basic processes used in STEM research with the required state and national science standards. The graduate students become respected role models for the high school students because of their STEM knowledge base and their passion for their research. Sharing enthusiasm for their chosen STEM field, as well as the application techniques to discover new ideas, the graduate students stimulate the interests of the classroom students and model authentic science process skills while highlighting the relevance of STEM research to K-12 student lives. The measurement of the student attitudes about science is gathered from pre and post interest surveys for the past four years. This partnership allows students, teachers, graduate students, and the public to

  18. Integrating local environmental research into K-12 science classrooms and the value of graduate student-educator partnerships (United States)

    Ward, N. D.; Petrik-Finley, R.


    Collaboration between researchers and K-12 educators enables an invaluable exchange of teaching philosophies and educational tools. Programs that partner graduate students with K-12 educators serve the dual purpose of training future educators and providing K-12 students with unique opportunities and perspectives. The benefits of this type of partnership include providing students with enhanced educational experiences and positive student-mentor relationships, training STEM graduate students in effective teaching strategies, and providing teachers with a firsthand resource for scientific information and novel educational materials. Many high school students have had little exposure to science beyond the classroom. Frequent interactions with "real-life" scientists can help make science more approachable and is an effective strategy for promoting science as a career. Here I describe my experiences and several lessons designed as a NSK GK-12 fellow. For example, a month-long unit on biogeochemical principles was framed as a crime scene investigation of a fish kill event in Hood Canal, Washington, in which students were given additional pieces of evidence to solve the mystery as they satisfied checkpoints in their understanding of key concepts. The evidence pieces included scientific plots, maps, datasets, and laboratory exercises. A clear benefit of this investigation-style unit is that students were able to learn the material at their individual pace. This structure allowed for a streamlined integration of differentiated materials such as simplified background readings or visual learning aids for struggling students or more detailed news articles and primary literature for more advanced students. Although the NSF GK-12 program has been archived, educators and researchers should pursue new partnerships, leveraging local and state-level STEM outreach programs with the goal of increasing national exposure of the societal benefits of such synergistic activities.

  19. Project ALERT: Forging New Partnerships to Improve Earth System Science Education for Pre-Service and In-Service Teachers (United States)

    Metzger, E. P.; Ambos, E. L.; Ng, E. W.; Skiles, J.; Simila, G.; Garfield, N.


    workshops have been enriched by the incorporation of earth and space science information and curricular materials from NASA. In addition, visits to Ames Research Center have given BAESI participants an opportunity to explore the Educator Resource Center, learn about NASA's programs for teachers and students, and experience presentations by NASA scientists engaged in cutting edge research about the earth system. Project ALERT demonstrates the power of a state-based partnership that unites scientists and educators with diverse perspectives and strengths in a synergistic effort to improve science education.

  20. Planetary Science Exploration Through 2050: Strategic Gaps in Commercial and International Partnerships (United States)

    Ghosh, A.


    Planetary science will see greater participation from the commercial sector and international space agencies. It is critical to understand how these entities can partner with NASA through 2050 and help realize NASA's goals in planetary science.

  1. Developing Elementary Science PCK for Teacher Education: Lessons Learned from a Second Grade Partnership (United States)

    Bradbury, Leslie U.; Wilson, Rachel E.; Brookshire, Laura E.


    In this self-study, two science educators partnered with two elementary teachers to plan, implement, and reflect on a unit taught in second grade classrooms that integrated science and language arts. The researchers hoped to increase their pedagogical content knowledge (PCK) for elementary science teaching so that they might use their experiences working in an elementary context to modify their practices in their elementary science method instruction. The research question guiding the study was: What aspects of our PCK for elementary science teaching do we as science educators develop by co-planning, co-teaching, and reflecting with second grade teachers? Data include transcripts of planning meetings, oral reflections about the experience, and videos of the unit being enacted. Findings indicate that managing resources for science teaching, organizing students for science learning, and reflecting on science teaching were themes prevalent in the data. These themes were linked to the model of PCK developed by Park and Oliver (Research in Science Education, 38, 261-284, 2008) and demonstrate that we developed PCK for elementary science teaching in several areas. In our discussion, we include several proposed changes for our elementary science methods course based on the outcomes of the study.

  2. Strengthening Community-University Research Partnerships: Science Shops in the Netherlands

    NARCIS (Netherlands)

    Mulder, Henk; Straver, Gerard; Hall, Budd; Tandon, Rajesh; Tremblay, Crystal


    Although they have been around for a long time already, the Science Shop approach is still seen as innovative in bridging the gap between science and civil society. The Dutch Science Shops are often taken as an example for similar activities abroad, and receive much support from the European

  3. Nanoscopic surfactant behavior of the porin MspA in aqueous media

    Directory of Open Access Journals (Sweden)

    Ayomi S. Perera


    Full Text Available The mycobacterial porin MspA is one of the most stable channel proteins known to date. MspA forms vesicles at low concentrations in aqueous buffers. Evidence from dynamic light scattering, transmission electron microscopy and zeta-potential measurements by electrophoretic light scattering indicate that MspA behaves like a nanoscale surfactant. The extreme thermostability of MspA allows these investigations to be carried out at temperatures as high as 343 K, at which most other proteins would quickly denature. The principles of vesicle formation of MspA as a function of temperature and the underlying thermodynamic factors are discussed here. The results obtained provide crucial evidence in support of the hypothesis that, during vesicle formation, nanoscopic surfactant molecules, such as MspA, deviate from the principles underlined in classical surface chemistry.

  4. The Federation of Earth Science Information Partners (ESIP Federation): Facilitating Partnerships that Work to Bring Earth Science Data into Educational Settings (United States)

    Freuder, R.; Ledley, T. S.; Dahlman, L.


    The Federation of Earth Science Information Partners (ESIP Federation, formed seven years ago and now with 77 member organizations is working to "increase the quality and value of Earth science products and services .for the benefit of the ESIP Federation's stakeholder communities." Education (both formal and informal) is a huge audience that we serve. Partnerships formed by members within the ESIP Federation have created bridges that close the gap between Earth science data collection and research and the effective use of that Earth science data to explore concepts in Earth system science by the educational community. The Earth Exploration Toolbook is one of those successful collaborations. The Earth Exploration Toolbook (EET, grew out of a need of the educational community (articulated by the Digital Library for Earth System Education (DLESE) community) to have better access to Earth science data and data analysis tools and help in effectively using them with students. It is a collection of web-accessible chapters, each featuring step-by-step instructions on how to use an Earth science dataset and data analysis tool to investigate an issue or concept in Earth system science. Each chapter also provides the teacher information on the outcome of the activity, grade level, standards addressed, learning goals, time required, and ideas for exploring further. The individual ESIP Federation partners alone could not create the EET. However, the ESIP Federation facilitated the partnering of members, drawing from data providers, researchers and education tool developers, to create the EET. Interest in the EET has grown since it went live with five chapters in July 2003. There are currently seven chapters with another six soon to be released. Monthly online seminars in which over a hundred educators have participated have given very positive feedback. Post workshop surveys from our telecon-online workshops indicate that

  5. A National Partnership-Based Summer Learning Initiative to Engage Underrepresented Students with Science, Technology, Engineering and Mathematics (United States)

    Melvin, Leland


    In response to the White House Educate to Innovate campaign, NASA developed a new science, technology, engineering, and mathematics (STEM) education program for non-traditional audiences that also focused on public-private partnerships and nationwide participation. NASA recognized that summer break is an often overlooked but opportune time to engage youth in STEM experiences, and elevated its ongoing commitment to the cultivation of diversity. The Summer of Innovation (SoI) is the resulting initiative that uses NASA's unique missions and resources to boost summer learning, particularly for students who are underrepresented, underserved and underperforming in STEM. The SoI pilot, launched in June 2010, is a multi-faceted effort designed to improve STEM teaching and learning through partnership, multi-week summer learning programs, special events, a national concluding event, and teacher development. The SoI pilot features strategic infusion of NASA content and educational resource materials, sustainability through STEM Learning Communities, and assessments of effectiveness of SoI interventions with other pilot efforts. This paper examines the inception and development of the Summer of Innovation pilot project, including achievements and effectiveness, as well as lessons learned for future efforts.

  6. RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene transcription. (United States)

    Yang, Chuan-Pin; Kuo, Yu-Liang; Lee, Yi-Chao; Lee, Kuen-Haur; Chiang, Chi-Wu; Wang, Ju-Ming; Hsu, Che-Chia; Chang, Wen-Chang; Lin, Ding-Yen


    The nucleolus is the cellular site of ribosomal (r)DNA transcription and ribosome biogenesis. The 58-kDa microspherule protein (MSP58) is a nucleolar protein involved in rDNA transcription and cell proliferation. However, regulation of MSP58-mediated rDNA transcription remains unknown. Using a yeast two-hybrid system with MSP58 as bait, we isolated complementary (c)DNA encoding Rad50-interacting protein 1 (RINT-1), as a MSP58-binding protein. RINT-1 was implicated in the cell cycle checkpoint, membrane trafficking, Golgi apparatus and centrosome dynamic integrity, and telomere length control. Both in vitro and in vivo interaction assays showed that MSP58 directly interacts with RINT-1. Interestingly, microscopic studies revealed the co-localization of MSP58, RINT-1, and the upstream binding factor (UBF), a rRNA transcription factor, in the nucleolus. We showed that ectopic expression of MSP58 or RINT-1 resulted in decreased rRNA expression and rDNA promoter activity, whereas knockdown of MSP58 or RINT-1 by siRNA exerted the opposite effect. Coexpression of MSP58 and RINT-1 robustly decreased rRNA synthesis compared to overexpression of either protein alone, whereas depletion of RINT-1 from MSP58-transfected cells enhanced rRNA synthesis. We also found that MSP58, RINT-1, and the UBF were associated with the rDNA promoter using a chromatin immunoprecipitation assay. Because aberrant ribosome biogenesis contributes to neoplastic transformation, our results revealed a novel protein complex involved in the regulation of rRNA gene expression, suggesting a role for MSP58 and RINT-1 in cancer development. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. Ligasi dan Transformasi Gen MSP1 Plasmodium falciparum Penyebab Malaria di Kota Jayapura

    Directory of Open Access Journals (Sweden)

    Arsyam Mawardi


    MSP1 is the most antigenic and expressed protein on merozoite surface when it infects the erythrocytes of malaria patients which leads to its use for vaccine therapy design development. The ligation and transformation process of the MSP1 gene is a gene duplication attempt for producing  the same product during expression. This study aimed to clone P. falciparum MSP-1 gene from tropical malaria patients in Jayapura using pJET1.2/blunt vectors and E. coli DH5a competent cells, to get the recombinant plasmid propagation of MSP1 gene. Blood that was positive for P. falciparum was molecularly processed, starting with genomic DNA isolation and then followed by PCR amplification, ligation into pJET1.2/blunt vector, and transformation into E. coli DH5α using the heat shock transformation method. The process was ended with PCR confirmation to confirm MSP1 gene insertion. The results showed that the presence of the  MSP1 gene in pJET1.2/blunt was successfully confirmed through PCR. From a total of 10 positive colonies grown in liquid culture,  plasmid was isolated. Electropherogram result presented bands  of about 1049bp, indicating the presence of the MSP1 gene in plasmid. Hence, MSP1 gene cloning using pJET1.2/blunt cloning vector and competent cell E. coli DH5α has been successfully performed.  Key words: Heat shock, ligation, MSP-1, P. falciparum, transformation

  8. The evaluation of CLIA, RIA and MSP-ELISA for measurement of thyroid hormones

    International Nuclear Information System (INIS)

    Jing Hua; Li Dan; Chen Yiguang; Zhou Huiqin; Xu Liyan


    To compare the characteristics of chemiluminescent immunoassay (CLIA), RIA and magnetic solid phase enzyme-linked immnosorbent assay (MSP-ELISA) in measuring thyroid hormones, TT 3 , TT 4 , FT 3 , FT 4 and TSH were tested in 40 samples of human serum and in standard samples of thyroid hormones by CLIA, RIA and MSP-ELISA respectively. The linearity, relativiy, precision, recovery of these three met hods were compared. The result showed that there were no statistical differences between CLIA, RIA and MSP-ELISA in linearity and relativity. CLIA was better than RIA and MSP-ELISA in precision and accuracy. (authors)

  9. Museums, zoos, and gardens: how formal-informal partnerships can impact urban students' performance in science. (United States)

    Weinstein, Meryle; Whitesell, Emilyn Ruble; Schwartz, Amy Ellen


    Informal science education institutions (ISEIs) are critical partners in public science education, as they support the science efforts of school systems by providing authentic opportunities for scientific inquiry. This study reports findings from an evaluation of urban advantage (UA), a collaboration between the New York City Department of Education and eight ISEIs designed to improve science education in New York City (NYC) middle schools. Now in its 10th year, the program harnesses the resources and expertise of NYC's ISEIs to (a) enhance the science content knowledge of middle school science teachers, (b) develop teachers' skills at using inquiry-based approaches in their classrooms, and (c) improve the science achievement of middle school students. We examine whether the UA program has led to increased student achievement on the eighth-grade New York State standardized science exam for students in participating schools; in supplemental analyses, we examine the effects on longer term (ninth-grade) outcomes. We use a difference-in-differences framework with school fixed effects to estimate the impact of attending a UA school in eighth grade on science achievement. Our key outcome is performance on New York State's eighth-grade intermediate-level science assessment; longer term outcomes include enrollment at specialized science, technology, engineering, and math high schools as well as taking and passing the high school (Regents) science exams. We find that attending a UA school increases student performance on the eighth-grade science exam by approximately 0.05 SD, and there is some evidence of small effects on Regents taking and passing rates. © The Author(s) 2014.

  10. A Component Approach to Collaborative Scientific Software Development: Tools and Techniques Utilized by the Quantum Chemistry Science Application Partnership

    Directory of Open Access Journals (Sweden)

    Joseph P. Kenny


    Full Text Available Cutting-edge scientific computing software is complex, increasingly involving the coupling of multiple packages to combine advanced algorithms or simulations at multiple physical scales. Component-based software engineering (CBSE has been advanced as a technique for managing this complexity, and complex component applications have been created in the quantum chemistry domain, as well as several other simulation areas, using the component model advocated by the Common Component Architecture (CCA Forum. While programming models do indeed enable sound software engineering practices, the selection of programming model is just one building block in a comprehensive approach to large-scale collaborative development which must also address interface and data standardization, and language and package interoperability. We provide an overview of the development approach utilized within the Quantum Chemistry Science Application Partnership, identifying design challenges, describing the techniques which we have adopted to address these challenges and highlighting the advantages which the CCA approach offers for collaborative development.

  11. Teaching and Learning Scientific Literacy and Citizenship in Partnership with Schools and Science Museums

    DEFF Research Database (Denmark)

    Dolin, Jens; Evans, Robert Harry; Quistgaard, Nana


    The purpose of this paper is to bring together research on learning and teaching in science – especially for scientific literacy and citizenship – with new insights into museum didactics in order to inform innovative ways of creating museum exhibits and visits and develop new ways of linking formal...... and informal learning environments. Knowledge from different domains that have evolved substantially over the past few decades is brought together with the intention of setting up some relatively concrete guidelines for arranging visits to science museums. First we examine new understandings of science...... learning in relation to the questions of why young people should learn science and what kind of science they should learn. We touch upon issues of scientific literacy and citizenship, dialogical processes, the nature of science, and inquiry-based teaching among others. Secondly, we relate our reflections...

  12. Changing Lives: The Baltimore City Community College Life Sciences Partnership with the University of Maryland, Baltimore (United States)

    Carroll, Vanessa G.; Harris-Bondima, Michelle; Norris, Kathleen Kennedy; Williams, Carolane


    Baltimore City Community College (BCCC) leveraged heightened student interest and enrollment in the sciences and allied health with Maryland's world-leading biotechnology industry to build a community college life sciences learning and research center right on the University of Maryland, Baltimore's downtown BioPark campus. The BCCC Life Sciences…

  13. Powerful Partnerships: The Worth of Embedding Masters Level Library Science Students in Undergraduate Classes (United States)

    Becnel, Kim; Moeller, Robin A.; Pope, Jon C.


    While experiential learning is recognized as an important pedagogical approach in Library and Information Science education, logistical hurdles can make implementing meaningful experiential projects challenging, especially in online courses. This paper will describe a project in which Library Science instructors were able to overcome common…

  14. RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene transcription

    International Nuclear Information System (INIS)

    Yang, Chuan-Pin; Kuo, Yu-Liang; Lee, Yi-Chao; Lee, Kuen-Haur; Chiang, Chi-Wu; Wang, Ju-Ming; Hsu, Che-Chia


    The nucleolus is the cellular site of ribosomal (r)DNA transcription and ribosome biogenesis. The 58-kDa microspherule protein (MSP58) is a nucleolar protein involved in rDNA transcription and cell proliferation. However, regulation of MSP58-mediated rDNA transcription remains unknown. Using a yeast two-hybrid system with MSP58 as bait, we isolated complementary (c)DNA encoding Rad50-interacting protein 1 (RINT-1), as a MSP58-binding protein. RINT-1 was implicated in the cell cycle checkpoint, membrane trafficking, Golgi apparatus and centrosome dynamic integrity, and telomere length control. Both in vitro and in vivo interaction assays showed that MSP58 directly interacts with RINT-1. Interestingly, microscopic studies revealed the co-localization of MSP58, RINT-1, and the upstream binding factor (UBF), a rRNA transcription factor, in the nucleolus. We showed that ectopic expression of MSP58 or RINT-1 resulted in decreased rRNA expression and rDNA promoter activity, whereas knockdown of MSP58 or RINT-1 by siRNA exerted the opposite effect. Coexpression of MSP58 and RINT-1 robustly decreased rRNA synthesis compared to overexpression of either protein alone, whereas depletion of RINT-1 from MSP58-transfected cells enhanced rRNA synthesis. We also found that MSP58, RINT-1, and the UBF were associated with the rDNA promoter using a chromatin immunoprecipitation assay. Because aberrant ribosome biogenesis contributes to neoplastic transformation, our results revealed a novel protein complex involved in the regulation of rRNA gene expression, suggesting a role for MSP58 and RINT-1 in cancer development. - Highlights: • RINT-1 is a novel MSP58-interacting protein. • RINT-1 is a nucleolar protein that suppresses ribosomal RNA gene transcription. • RINT-1 and MSP58 cooperate to suppress ribosomal RNA gene transcription. • RINT-1, MSP58, and UBF form a complex on the rDNA promoter.

  15. The Catalyst Scholarship Program at Hunter College. A Partnership among Earth Science, Physics, Computer Science and Mathematics (United States)

    Salmun, Haydee; Buonaiuto, Frank


    The Catalyst Scholarship Program at Hunter College of The City University of New York (CUNY) was established with a four-year award from the National Science Foundation (NSF) to fund scholarships to 40 academically talented but financially disadvantaged students majoring in four disciplines of science, technology, engineering and mathematics…

  16. Science Teachers' Views and Stereotypes of Religion, Scientists and Scientific Research: A call for scientist-science teacher partnerships to promote inquiry-based learning (United States)

    Mansour, Nasser


    Despite a growing consensus regarding the value of inquiry-based learning (IBL) for students' learning and engagement in the science classroom, the implementation of such practices continues to be a challenge. If science teachers are to use IBL to develop students' inquiry practices and encourage them to think and act as scientists, a better understanding of factors that influence their attitudes towards scientific research and scientists' practices is very much needed. Within this context there is a need to re-examine the science teachers' views of scientists and the cultural factors that might have an impact on teachers' views and pedagogical practices. A diverse group of Egyptian science teachers took part in a quantitative-qualitative study using a questionnaire and in-depth interviews to explore their views of scientists and scientific research, and to understand how they negotiated their views of scientists and scientific research in the classroom, and how these views informed their practices of using inquiry in the classroom. The findings highlighted how the teachers' cultural beliefs and views of scientists and scientific research had constructed idiosyncratic pedagogical views and practices. The study suggested implications for further research and argued for teacher professional development based on partnerships with scientists.


    Over the past decade genomics, proteomics and metabonomics technologies have transformed the science of toxicology, and concurrent advances in computing and informatics have provided management and analysis solutions for this onslaught of toxicogenomic data. EPA has been actively...

  18. Internet Links for Science Education: Student-Scientist Partnerships (edited by Karen Cohen) (United States)

    Barden, Linda M.


    Plenum: New York, 1997. xx + 260 pp. Figs., tables, photos. 15 x 22.8 cm. ISBN 0-306-45558-7. $27.50. Science education is undergoing an upheaval more fundamental than the one that occurred in the aftermath of Sputnik. Research during the past 40 years has led to a radical change in the way we view children's learning of science. The National Science Education Standards (NSES) suggest a new model for teaching science based upon these research findings. Societal changes, particularly changes in business, have put pressure on schools to alter the emphasis of curricula from rote memory and individual competition to problem solving using a variety of technological skills and teamwork/team competition. This timely book addresses all these issues by describing projects that K-12 teachers can use to achieve the goals set forth by both NSES and business. It also provides scientists with examples of how they and their coworkers might better interact with K-12 science education to encourage a more scientifically literate society. Finally, it includes suggestions for future research in science education.

  19. Modular Integrated Stackable Layers (MISL) MI_MSP430A Board Design Document (BDD) (United States)

    Yim, Hester


    This is a board-level design document for Modular Integrated Stackable Layers (MISL) MI_MSP430A board (PIN MSP430F5438A). The Board Design Document (BDD) contains the description, features of microcontroller, electrical and mechanical design, and drawings.

  20. Education, Outreach, and Diversity Partnerships and Science Education Resources From the Center for Multi-scale Modeling of Atmospheric Processes (United States)

    Foster, S. Q.; Randall, D.; Denning, S.; Jones, B.; Russell, R.; Gardiner, L.; Hatheway, B.; Johnson, R. M.; Drossman, H.; Pandya, R.; Swartz, D.; Lanting, J.; Pitot, L.


    The need for improving the representation of cloud processes in climate models has been one of the most important limitations of the reliability of climate-change simulations. The new National Science Foundation- funded Center for Multi-scale Modeling of Atmospheric Processes (CMMAP) at Colorado State University (CSU) is a major research program addressing this problem over the next five years through a revolutionary new approach to representing cloud processes on their native scales, including the cloud-scale interactions among the many physical and chemical processes that are active in cloud systems. At the end of its first year, CMMAP has established effective partnerships between scientists, students, and teachers to meet its goals to: (1) provide first-rate graduate education in atmospheric science; (2) recruit diverse undergraduates into graduate education and careers in climate science; and (3) develop, evaluate, and disseminate educational resources designed to inform K-12 students, teachers, and the general public about the nature of the climate system, global climate change, and career opportunities in climate science. This presentation will describe the partners, our challenges and successes, and measures of achievement involved in the integrated suite of programs launched in the first year. They include: (1) a new high school Colorado Climate Conference drawing prestigious climate scientists to speak to students, (2) a summer Weather and Climate Workshop at CSU and the National Center for Atmospheric Research introducing K-12 teachers to Earth system science and a rich toolkit of teaching materials, (3) a program from CSU's Little Shop of Physics reaching 50 schools and 20,000 K-12 students through the new "It's Up In the Air" program, (4) expanded content, imagery, and interactives on clouds, weather, climate, and modeling for students, teachers, and the public on The Windows to the Universe web site at University Corporation for Atmospheric Research

  1. Introduction to embedded systems using microcontrollers and the MSP430

    CERN Document Server

    Jiménez, Manuel; Couvertier, Isidoro


    This textbook serves as an introduction to the subject of embedded systems design, using microcontrollers as core components.  It develops concepts from the ground up, covering the development of embedded systems technology, architectural and organizational aspects of controllers and systems, processor models, and peripheral devices. Since microprocessor-based embedded systems tightly blend hardware and software components in a single application, the book also introduces the subjects of data representation formats, data operations, and programming styles. The practical component of the book is tailored around the architecture of a widely used Texas Instrument’s microcontroller, the MSP430. Instructor’s supplemental materials available through the book web site include solutions to selected problems and exercises and power point slides for lectures. The site also includes materials for students that include links to application examples and to sites elsewhere in the web with application notes, downloadab...

  2. Performance of the Digital Science Partnership Remotely-Operated 0.5-Meter Corrected Dall-Kirkham Telescopes (United States)

    Kielkopf, John F.; Carter, B.; Brown, C.; Hart, R.; Hay, J.; Waite, I.


    The Digital Science Partnership, a collaboration of the University of Louisville and the University of Southern Queensland, operates a pair of 0.5-meter telescopes for teaching, research, and informal education. The instruments were installed at sites near Toowoomba, Australia, and Louisville, Kentucky in 2006. The Planewave Instruments optical systems employ a unique Dall-Kirkham design incorporating a two-element corrector that demagnifies the image, flattens the focal plane, and reduces coma. These instruments have a moderately fast f/6.8 focal ratio and maintain image quality with little vignetting over a field 42 mm in diameter (0.7 degree). With a 9-micron pixel CCD such as the KAF-6303E, the image scale of 0.55 seconds of arc per pixel typically yields seeing-limited image quality at our sites. The telescopes and their enclosure are operated in a live remote observing mode through Linux-based software, including a dome-control system that uses RFID tags for absolute rotation encoding. After several months of testing and development we have examples of images and photometry from both sites that illustrate the performance of the system. We will discuss image quality, as well as practical matters such as pointing accuracy and field acquisition, auto-guiding, communication latency in large file transfer, and our experience with remote observing assisted by teleconferencing. Time-delay-integration (TDI) imaging, in which the telescope is stationary while the CCD is clocked to track in right ascension, is under study. The technique offers wide fields of view with very high signal-to-noise ratio, and can be implemented in robotically operated instruments used in monitoring, rapid-response, and educational programs. Results for conventional and TDI imaging from the dark site in Australia compared to the brighter suburban site in Kentucky show the benefits of access to dark sites through international partnerships that remote operation technology offers.

  3. Addressing medical school diversity through an undergraduate partnership at Texas A&M Health Science Center: a blueprint for success. (United States)

    Parrish, Alan R; Daniels, Dennis E; Hester, R Kelly; Colenda, Christopher C


    Imperative to increasing diversity in the physician workforce is increasing the pool of qualified underrepresented minority applicants to medical schools. With this goal in mind, the Texas A&M Health Science Center College of Medicine (A&M College of Medicine) has partnered with Prairie View A&M University (PVAMU), a historically black college and university that is a component of the Texas A&M university system, to develop the undergraduate medical academy (UMA). The UMA was established by legislative mandate in 2003 and is a state-funded program. The authors describe the development of partnership between the A&M College of Medicine and PVAMU, focusing on the key attributes that have been identified for success. The administrative structure of the UMA ensures that the presidents of the two institutions collaborate to address issues of program oversight and facilitates a direct relationship between the dean and associate dean for academic affairs of A&M College of Medicine and the director of the UMA to define the program objectives and structure. The authors delineate the admission process to the UMA, as well as the academic requirements of the program. Students attend lecture series during the academic year and participate in summer programs on the A&M College of Medicine campus in addition to receiving intensive academic counseling and opportunities for tutoring in several subjects. The authors also describe the initial success in medical school admissions for UMA students. This partnership provides a model blueprint that can be adopted and adapted by other medical schools focused on increasing diversity in medicine.

  4. Community Science: creating equitable partnerships for the advancement of scientific knowledge for action. (United States)

    Lewis, E. S.; Gehrke, G. E.


    In a historical moment where the legitimacy of science is being questioned, it is essential to make science more accessible to the public. Active participation increases the legitimacy of projects within communities (Sidaway 2009). Creating collaborations in research strengthens not only the work by adding new dimensions, but also the social capital of communities through increased knowledge, connections, and decision making power. In this talk, Lewis will discuss how engagement at different stages of the scientific process is possible, and how researchers can actively develop opportunities that are open and inviting. Genuine co-production in research pushes scientists to work in new ways, and with people from different backgrounds, expertise, and lived experiences. This approach requires a flexible and dynamic balance of learning, sharing, and creating for all parties involved to ensure more meaningful and equitable participation. For example, in community science such as that by Public Lab, the community is at the center of scientific exploration. The research is place-based and is grounded in the desired outcomes of community members. Researchers are able to see themselves as active participants in this work alongside community members. Participating in active listening, developing plans together, and using a shared language built through learning can be helpful tools in all co-production processes. Generating knowledge is powerful. Through genuine collaboration and co-creation, science becomes more relevant. When community members are equitable stakeholders in the scientific process, they are better able to engage and advocate for the changes they want to see in their communities. Through this talk, session attendees will learn about practices that promote equitable participation in science, and hear examples of how the community science process engages people in both the knowledge production, and in the application of science.

  5. Integrating Environmental Science and the Economy: Innovative Partnerships between the Private Sector and Research Infrastructures

    Directory of Open Access Journals (Sweden)

    Abad Chabbi


    Full Text Available The present paper is a preliminary analysis of the funding, organizational culture, environmental, and innovation challenges that are currently faced by Environmental Research Infrastructures (ERI and private enterprises working together. We contend there is a strong case for building creative collaboration models across these sectors that also require to new management tools to effectively generate economically-driven solutions to the global society at large in the face of climate change. To that end, public/private stakeholders that are likely to partner to address climate change also face new frontiers in how they will structurally and organizationally work together. We explore these issues around changing political, scientific, commercial environments; partnerships models; barriers in bridging these communities; and the role of formal project management processes. There is no one solution to fit all conditions that can bring together a specific public/private enterprise that incorporates a research infrastructure. However, we have provided two examples of collaborative models of public/private enterprises to highlight how these issues can be addressed, and to foster future dynamic and creative solutions to this problem.

  6. 9th Pacific Basin Nuclear Conference. Nuclear energy, science and technology - Pacific partnership. Proceedings Volume 2

    International Nuclear Information System (INIS)


    The theme of the 9th Pacific Basin Nuclear Conference held in Sydney from 1-6 May 1994, embraced the use of atom in energy production and in science and technology. The focus was on selected topics of current and on-going interest to countries around the Pacific Basin. The two-volume proceedings include both invited and contributed papers which have been indexed separately. This document, Volume 2 covers the following topics: education and training in Nuclear Science, public acceptance, nuclear safety and radiation protection, nuclear fuel resources and their utilisation, research reactors, cyclotrons and accelerators. refs., tabs., figs., ills

  7. In the Footsteps of Roger Revelle: a Partnership between SIO, ONR and Middle School Science Students (United States)

    Brice, D.; Appelgate, T. B.; Foley, S.; Knox, R. A.; Mauricio, P.


    Now in its seventh year, “In the Footsteps of Roger Revelle” (IFRR) is a middle school science education program that draws student interest, scientific content and coherence with National Science Standards from real-time research at sea in fields of physical science. As a successful collaboration involving Scripps Institution of Oceanography (SIO), National Science Foundation (NSF),Office of Naval Research (ONR), and San Marcos Middle School (SMMS), IFRR brings physical oceanography and related sciences to students at the San Marcos Middle School in real-time from research vessels at sea using SIO's HiSeasNet satellite communication system. With a generous grant from ONR, students are able to tour the SIO ships and spend a day at sea doing real oceanographic data collection and labs. Through real-time and near-realtime broadcasts and webcasts, students are able to share data with scientists and gain an appreciation for the value of biogeochemical research in the field as it relates to their classroom studies. The primary impact on these students is an appreciation of ocean science as it relates to their lives. Interaction with scientists and researchers as well as crew members gives students insights into not only possible career paths, but the vital importance of cutting edge oceanographic research on our society. With their science teacher on the ship as an education outreach specialist or ashore guiding students in their interactions with selected scientists at sea, students observe shipboard research being carried out live via videoconference, Skype, daily e-mails, interviews, digital whiteboard sessions, and web interaction. Students then research, design, develop, deploy, and field-test their own data-collecting physical oceanography instruments in their classroom. The online interactive curriculum encourages active inquiry with intellectually stimulating problem- solving, enabling students to gain critical insight and skill while investigating some of

  8. Nurture thru Nature: Creating Natural Science Identities in Populations of Disadvantaged Children through Community Education Partnership (United States)

    Camasso, Michael J.; Jagannathan, Radha


    In this article we describe the development, implementation, and some of the early impacts of Nurture thru Nature (NtN), an American after-school and summer program designed to introduce elementary school students in disadvantaged, urban public schools to natural science and environmental education. The program, which began operations in 2010 as a…

  9. Opening the Classroom Door: Professional Learning Communities in the Math and Science Partnership Program (United States)

    Hamos, James E.; Bergin, Kathleen B.; Maki, Daniel P.; Perez, Lance C.; Prival, Joan T.; Rainey, Daphne Y.; Rowell, Ginger H.; VanderPutten, Elizabeth


    This article looks at how professional learning communities (PLCs) have become an operational approach for professional development with potential to de-isolate the teaching experience in the fields of science, technology, engineering, and mathematics (STEM). The authors offer a short synopsis of the intellectual origins of PLCs, provide multiple…

  10. Cataclysms and Catastrophes: A Case Study of Improving K-12 Science Education Through a University Partnership (United States)

    Fennell, T.; Ellins, K. K.; Morris, M.; Christeson, G.


    The K-12 science teacher is always seeking ways of improving and updating their curriculum by integrating the latest research into their most effective classroom activities. However, the daily demands of delivering instruction to large numbers of students coupled with the rapid advances in some fields of science can often overwhelm this effort. The NSF-sponsored Cataclysms and Catastrophes curriculum, developed by scientists from the The University of Texas at Austin Institute for Geophysics (UTIG) and Bureau of Economic Geology (BEG), middle and high school teachers, and UT graduate students (NSF GK-12 fellows) working together through the GK-12 program, is a textbook example of how universities can facilitate this quest, benefiting education at both K-12 and university levels. In 1992, "The Great K-T Extinction Debate" was developed as an activity in the Planet Earth class at the Liberal Arts and Science Academy of Austin as an interdisciplinary approach to science. Taking advantage of the media attention generated by the impact scenario for the K-T extinction, the activity consists of students participating in a simulated senate hearing on the potential causes of the K-T extinction and their implications for society today. This activity not only exposes students to the wide range of science involved in understanding mass extinctions, but also to the social, political and economic implications when this science is brought into the public arena and the corresponding use of data in decision making and disaster preparedness. While "The Great K-T Extinction Debate" was always a popular and effective activity with students, it was in desperate need of updating to keep pace with the evolving scientific debate over the cause of the K-T extinction and the growing body of impact evidence discovered over the past decade. By adding two inquiry-based learning activities that use real geophysical data collected by scientists studying the buried Chicxulub feature as a

  11. Collaborations and Partnerships in NASA’s Earth Science Data Systems

    Directory of Open Access Journals (Sweden)

    Hampapuram K. Ramapriyan


    Full Text Available NASA has been collecting Earth observation data from spaceborne instruments since 1960. Today, there are tens of satellites orbiting the Earth and collecting frequent global observations for the benefit of mankind. Collaboration between NASA and organizations in the US and other countries has been extremely important in maintaining the Earth observation capabilities as well as collecting, organizing and managing the data. These collaborations have occurred in the form of: 1. NASA’s developing and launching spacecraft and instruments for operation by other agencies; 2. Instruments from collaborating organizations being flown on NASA satellites; and 3. Instruments from NASA being flown on satellites from collaborating organizations. In addition, there are collaborations such as joint science teams, data exchanges, and participation in international organizations to promote interoperability of various data systems. The purpose of this paper is to describe some of the Earth science data-related collaborative efforts in which NASA participates, and highlight a few results relevant to Earth system science research obtained through such collaborations.

  12. FAST's Discovery of a New Millisecond Pulsar (MSP) toward the Fermi-LAT unassociated source 3FGL J0318.1+0252 (United States)

    Wang, Pei; Li, Di; Zhu, Weiwei; Zhang, Chengmin; Yan, Jun; Hou, Xian; Clark, Colin J.; Saz Parkinson, Pablo M.; Michelson, Peter F.; Ferrara, Elizabeth C.; Thompson, David J.; Smith, David A.; Ray, Paul S.; Kerr, Matthew; Shen, Zhiqiang; Wang, Na; Fermi-LAT Collaboration


    The Five hundred-meter Aperture Spherical radio Telescope (FAST), operated by the National Astronomical Observatories, Chinese Academy of Sciences, has discovered a radio millisecond pulsar (MSP) coincident with the unassociated gamma-ray source 3FGL J0318.1+0252 (Acero et al. 2015 ApJS, 218, 23), also known as FL8Y J0318.2+0254 in the recently released Fermi Large Area Telescope (LAT) 8-year Point Source List (FL8Y).

  13. Msp1 Is a Membrane Protein Dislocase for Tail-Anchored Proteins. (United States)

    Wohlever, Matthew L; Mateja, Agnieszka; McGilvray, Philip T; Day, Kasey J; Keenan, Robert J


    Mislocalized tail-anchored (TA) proteins of the outer mitochondrial membrane are cleared by a newly identified quality control pathway involving the conserved eukaryotic protein Msp1 (ATAD1 in humans). Msp1 is a transmembrane AAA-ATPase, but its role in TA protein clearance is not known. Here, using purified components reconstituted into proteoliposomes, we show that Msp1 is both necessary and sufficient to drive the ATP-dependent extraction of TA proteins from the membrane. A crystal structure of the Msp1 cytosolic region modeled into a ring hexamer suggests that active Msp1 contains a conserved membrane-facing surface adjacent to a central pore. Structure-guided mutagenesis of the pore residues shows that they are critical for TA protein extraction in vitro and for functional complementation of an msp1 deletion in yeast. Together, these data provide a molecular framework for Msp1-dependent extraction of mislocalized TA proteins from the outer mitochondrial membrane. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Partnerships in Nuclear Science and Technology contributing to the `high road` to the future

    Energy Technology Data Exchange (ETDEWEB)

    Garnett, H. [Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW (Australia)


    The focus of this AINSE conference is a celebration of the many contributions that nuclear science and technology have made to the development of knowledge over the past forty years. While understanding and reviewing the past can help us along the road to the future, and in particular help us avoid mistakes of the past, such an historical review cannot determine what the future road will be. Underpinning many of the emerging technologies, considered likely to contribute to socioeconomic development, are both material science and various processing technologies. There is also a need to better understand natural processes. An analysis of the structure, function and performance of materials requires the use of the fundamental probes, neutrons, charged particles and X-rays. Understanding natural processes is facilitated by isotopes. The past has delivered a solid knowledge base for understanding the properties of these probes and their potential applications. Each has unique properties and access to all types of probe is required. Recent innovations, in materials development, have themselves resulted in the design of facilities to deliver these probes more efficiently and effectively and in the construction of better detectors to `visualise` the outcome, thereby allowing a broader range of questions to be answered. Access to solutions for materials and processing problems will be required in an ever-decreasing time span for any company wishing to maintain the competitive edge. Nuclear science and technology can and will be an essential component of this innovation cycle, assisting Australian enterprises to be at the leading edge of competitive markets. To achieve this, we must not just create knowledge but also create the opportunities to assist in adding value, influence external environment and create the networks to make the `high road` a reality

  15. Partnerships in Nuclear Science and Technology contributing to the 'high road' to the future

    International Nuclear Information System (INIS)

    Garnett, H.


    The focus of this AINSE conference is a celebration of the many contributions that nuclear science and technology have made to the development of knowledge over the past forty years. While understanding and reviewing the past can help us along the road to the future, and in particular help us avoid mistakes of the past, such an historical review cannot determine what the future road will be. Underpinning many of the emerging technologies, considered likely to contribute to socioeconomic development, are both material science and various processing technologies. There is also a need to better understand natural processes. An analysis of the structure, function and performance of materials requires the use of the fundamental probes, neutrons, charged particles and X-rays. Understanding natural processes is facilitated by isotopes. The past has delivered a solid knowledge base for understanding the properties of these probes and their potential applications. Each has unique properties and access to all types of probe is required. Recent innovations, in materials development, have themselves resulted in the design of facilities to deliver these probes more efficiently and effectively and in the construction of better detectors to 'visualise' the outcome, thereby allowing a broader range of questions to be answered. Access to solutions for materials and processing problems will be required in an ever-decreasing time span for any company wishing to maintain the competitive edge. Nuclear science and technology can and will be an essential component of this innovation cycle, assisting Australian enterprises to be at the leading edge of competitive markets. To achieve this, we must not just create knowledge but also create the opportunities to assist in adding value, influence external environment and create the networks to make the 'high road' a reality

  16. A Science-Faith Partnership to Provide Education and Facilitate Action on Climate Change and Energy Use (United States)

    Cervenec, J. M.; Hitzhusen, G.; Ward, S.; Foster, C.


    In 2009, the Byrd Polar Research Center (BPRC) and Ohio Interfaith Power and Light (OhIPL) collaborated on a climate change education summit for scientists and clergy. Since that first program, a robust partnership has been nurtured where researchers at the center regularly contribute to events within the faith community. In 2014 alone, BPRC supported OhIPL in hosting a Teach-In event on climate change before a live audience that was simultaneously broadcast to three remote sites across Ohio; a State of the Climate event at the Ohio Statehouse that featured presentations by a scientist, a policymaker, and a member of the faith community; and an Earthkeeping Summit to bring together members of the faith community from across Ohio. OhIPL has helped BPRC fulfill one of our mission objectives of communicating science to a broad community. OhIPL engages houses of worship of all denominations through faith and education with a goal of moving them towards actions that reduce energy consumption. Houses of worship take actions for various reasons - including creation care, concerns of social justice related to climate change, or a desire to save money through building efficiency.

  17. Safe Shores and Resilient Transit Corridors: Using Science, Design, and Stakeholder Partnerships to Address Connecticut's Coastal Vulnerabilities (United States)

    French, R. A.; Felson, A. J.; Kirmmse, E.; Hagemann, K.


    Connecticut's densely developed coastline is highly vulnerable to sea level rise and coastal storms. 95% of the state's entire population lives within 50 miles of the shore. Connecticut has more than $542 billion in insured assets in harms way, only Florida has a greater exposure. As part of the state of Connecticut Phase 1 application for the HUD National Disaster Resilience Competition, the Connecticut Institute for Resilience and Climate Adaptation (CIRCA) at the University of Connecticut undertook an assessment of coastal vulnerabilities, including the impacts of sea level rise on the frequency of flooding, socioeconomic factors, critical infrastructure, and housing using data collected from federal, state, and municipal sources. Connecticut's unique geology, characterized by a glaciated coastline with highly erodible former deltas and elevated ridgelines extending out to rocky headlands, became the basis of the climate adaptation approach. Together with a nine state agency workgroup, municipal and regional government, and non-profit and industry representatives, CIRCA and the Yale UED lab developed a long-term urban redevelopment solution of resilient access and egress corridors layered over ridgelines and resilient zones of transit oriented economic development linked to shoreline communities. This concept can be applied in both Connecticut's coastal cities like New Haven and its smaller towns. The process demonstrated the effective partnership between the universities and state agencies in bringing the science of flood modeling and mapping together with innovative design to create solutions for climate adaptation. However, it also revealed significant gaps in data availability to analyze the economic and social drivers for adopting different adaptation strategies. Furthermore, the accuracy of current flood mapping tools needs to be improved to predict future flooding at the municipal project scale. As Connecticut and other states move forward with resilience

  18. Proceedings of the 3rd Biennial Conference of the Society for Implementation Research Collaboration (SIRC) 2015: advancing efficient methodologies through community partnerships and team science


    Lewis, Cara; Darnell, Doyanne; Kerns, Suzanne; Monroe-DeVita, Maria; Landes, Sara J.; Lyon, Aaron R.; Stanick, Cameo; Dorsey, Shannon; Locke, Jill; Marriott, Brigid; Puspitasari, Ajeng; Dorsey, Caitlin; Hendricks, Karin; Pierson, Andria; Fizur, Phil


    Table of contents Introduction to the 3rd Biennial Conference of the Society for Implementation Research Collaboration: advancing efficient methodologies through team science and community partnerships Cara Lewis, Doyanne Darnell, Suzanne Kerns, Maria Monroe-DeVita, Sara J. Landes, Aaron R. Lyon, Cameo Stanick, Shannon Dorsey, Jill Locke, Brigid Marriott, Ajeng Puspitasari, Caitlin Dorsey, Karin Hendricks, Andria Pierson, Phil Fizur, Katherine A. Comtois A1: A behavioral economic perspective ...

  19. Ludvig, Zsuzsa (ed.) Eurasian challenges : partnerships with Russia and other issues of the post-Soviet area. East European Studies, No. 4, Budabest Institute of World Economics and Regional Studies, Hungarian Academy of Sciences, 2013, 163pp. / Csab

    Index Scriptorium Estoniae

    Weiner, Csaba


    Arvustus: Ludvig, Zsuzsa (ed.) Eurasian challenges : partnerships with Russia and other issues of the post-Soviet area. Budabest Institute of World Economics and Regional Studies, Hungarian Academy of Sciences, 2013

  20. Partnership Opportunities In Earth System Science Education Between Historically Black and Historically White Universities: Elizabeth City State University and the University of New Hampshire (United States)

    Williams, J. E.; Hayden, L. B.; Wake, C. P.; Varner, R. K.; Graham, K.; Rock, B. N.; Hale, S.; Hurtt, G. C.; Porter, W.; Blackmon, R.; Bryce, J. G.; Branch, B. D.; Johnson, J. E.


    Federal efforts to promote the participation of underrepresented students in the science, technology, engineering and mathematics disciplines (STEM) in higher education have been in effect over several decades. The Science and Engineering Equal Opportunities Act of 1980 aimed to create equal opportunity in the STEM disciplines by promoting and broadening the participation of underrepresented talent in science and engineering. Since that time, federal agencies such as the National Science Foundation, NOAA and NASA, scientific organizations such as the American Geophysical Union, and other organizations such as the Educational Testing Service have created programs, diversity plans and cutting edge reports designed to further explicate the need to broaden the participation of underrepresented student talent in these disciplines. Despite increases in the degrees awarded to underrepresented students in the STEM disciplines, enhancing diversity in these disciplines continues to remain a significant challenge. This paper describes a strategic approach to this challenge via the development of a collaborative partnership model between two universities: the historically black Elizabeth City State University (ESCU) and the historically white University of New Hampshire (UNH). The alliance, built on a mutually-agreed upon set of partnership principles, strives to enhance opportunities for underrepresented students to pursue careers in STEM disciplines, specifically those in Earth system science and remote sensing. In examining the partnership, six promising practices that help advance its success come to the forefront. These practices include institutional commitment and faculty engagement, mutual respect and shared time commitment, identifying engaged leadership, engaging critical change agents, initiating difficult dialogues, and preparing for growth and evolution. Outcomes of the partnership to date include the successful submission and funding of four collaborative


    Directory of Open Access Journals (Sweden)

    Magno Melo


    Full Text Available Este artigo apresenta a pesquisa e definição dos componentes necessários ao desenvolvimento de um robô autônomo a ser utilizado em competição de sumô de robôs. Este tipo de equipamento, também conhecido como robô segue faixa, será desenvolvido com o objetivo de introdução à robótica, bem como do estudo do funcionamento e aplicabilidade do microcontrolador MSP430, o qual será o componente responsável pela automação deste robô. Assim, a partir desta definição, faz-se necessária a especificação dos demais componentes integrantes do equipamento (chassi, meio de locomoção, motores, sensores e alimentação de tal forma que o robô possa desempenhar adequadamente as tarefas para os quais o mesmo foi idealizado.

  2. Building partnerships to produce actionable science to support climate-informed management decisions: North Central Climate Science Center example (United States)

    Lackett, J.; Ojima, D. S.; McNeeley, S.


    As climate change impacts become more apparent in our environment, action is needed to enhance the social-ecological system resilience. Incorporating principles which lead to actionable research and project co-development, when appropriate, will facilitate building linkages between the research and the natural resource management communities. In order to develop strategies to manage for climatic and ecosystem changes, collaborative actions are needed between researchers and resource managers to apply appropriate knowledge of the ecosystem and management environments to enable feasible solutions and management actions to respond to climate change. Our team has been involved in developing and establishing a research and engagement center, the North Central Climate Science Center (NC CSC), for the US Department of Interior, to support the development and translation of pertinent climate science information to natural resource managers in the north central portion of the United States. The NC CSC has implemented a platform to support the Resource for Vulnerability Assessment, Adaptation, and Mitigation Projects (ReVAMP) with research, engagement, and training activities to support resource managers and researchers. These activities are aimed at the co-production of appropriate response strategies to climate change in the region, in particular to drought-related responses. Through this platform we, with other partners in the region, including the Department of Interior and the Department of Agriculture, are bringing various training tools, climate information, and management planning tools to resource managers. The implementation of ReVAMP has led to development of planning efforts which include a more explicit representation of climate change as a driver of drought events in our region. Scenario planning provides a process which integrates management goals with possible outcomes derived from observations and simulations of ecological impacts of climate change. Co

  3. Marine spatial planning (MSP: A first step to ecosystem-based management (EBM in the Wider Caribbean

    Directory of Open Access Journals (Sweden)

    John C Ogden


    Full Text Available The rapid decline of coastal ecosystems of the Wider Caribbean is entering its fifth decade. Some of the best science documenting this decline and its causes has been done by the laboratories of the Association of Marine Laboratories of the Caribbean (AMLC. Alarmed at the trends, Caribbean conservation pioneers established marine protected areas (MPAs which spread throughout the region. Unfortunately, many have little or no protection and are now known to be too small to be effective in sustaining coastal ecosystems. Marine spatial planning (MSP holds much promise to encompass the large geographic scales of the ecological processes and human impacts that influence coastal ecosystems and adjacent lands. The AMLC, through the scientific expertise and the national political connections of its member institutions, is well-positioned to help implement a pilot project. MSP a first step in ecosystem-based management and has had considerable success elsewhere. It holds our best chance of sustaining human use and conserving the coral reefs and associated ecosystems. Rev. Biol. Trop. 58 (Suppl. 3: 71-79. Epub 2010 October 01.La rápida disminución de los ecosistemas costeros del Mar Caribe está entrando en su quinta década. Algunos de los mejores aportes científicos que documentan este descenso y sus causas han sido realizados por los laboratorios de la Asociación de Laboratorios Marinos del Caribe (ALMC. Alarmados por las tendencias, los pioneros de la conservación del Caribe establecieron áreas marinas protegidas (MPAs que se extendieron por toda la región. Desafortunadamente, muchas de estas áreas tienen poca o ninguna protección y ahora se conoce que son demasiado pequeñas para ser efectivas en el mantenimiento de los ecosistemas costeros. La planificación espacial marina (MSP es promisoria para englobar las grandes escalas geográficas de los procesos ecológicos y los impactos humanos que influyen en los ecosistemas costeros y las

  4. Consumer health information partnerships: the health science library and multitype library system. (United States)

    Hollander, S


    The University of Illinois Library of the Health Sciences at Rockford (LHS-Rockford) long has honored a commitment to serving the health information needs of the greater Rockford community. Utilization data collected over the past five years indicate that approximately 50% of reference transactions involve persons not affiliated with the university. In early 1994, LHS-Rockford submitted a proposal to the Northern Illinois Library System (NILS), a multitype system spanning twelve counties in northwestern Illinois, asking to serve as a resource library for improving medical and health information services provided by the 138 NILS member libraries. The NILS funded this pilot project as part of an effort to implement a new strategic plan, which encouraged member libraries to form networks to provide reference back-up service. LHS-Rockford acquired InfoTrac's Health Reference Center, a consumer health information database, and set up a dedicated workstation near the information and circulation desk. Referral guidelines were established and the project was promoted among NILS member libraries. Activities were documented in order to track project success in terms of referrals and outcomes. The demonstration project was very successful, and it proves public consumers seeking health information can benefit greatly from this type of cooperative arrangement.

  5. Genotipificación de Plasmodium falciparum por PCR múltiple por medio de los genes msp1, msp2 y glurp, en cuatro localidades de Colombia

    Directory of Open Access Journals (Sweden)

    Sandra Milena Barrera


    Conclusiones. Nuestros resultados demuestran que el marcador molecular msp1 no proporciona información útil para diferenciar las poblaciones parasitarias de P. falciparum. El gen msp2 es apropiado para evaluar la diversidad genética, pero requiere ensayos más finos que permitan diferenciar claramente el polimorfismo de tamaño en las dos familias. Los resultados obtenidos con el gen glurp evidenciaron una gran diversidad genética en las poblaciones de P. falciparum que circulan en el país y sugieren que este gen puede ser útil para diferenciar nuevas infecciones de infecciones recurrentes o recrudecimientos.

  6. The physical and functional interaction of NDRG2 with MSP58 in cells

    International Nuclear Information System (INIS)

    Zhang Jing; Liu Junye; Li Xia; Li Fuyang; Wang Lifeng; Zhang Jian; Liu Xinping; Shen Lan; Liu Na; Deng Yanchun; Yang Angang; Han Hua; Zhao Mujun; Yao Libo


    NDRG2, a member of N-Myc downstream regulated gene family, exerts the important functions in cell differentiation and tumor suppression. Although the ectopic expressed Ndrg2 inhibits the proliferation of tumor cells, its intracellular signal transduction pathway is hardly known. Here, we identified MSP58, a 58-kDa microspherule protein, as an interacting partner of human Ndrg2 by using yeast two-hybrid screening. The interaction was confirmed by glutathione S-transferase pull-down assay in vitro and by co-immune-precipitation assay in vivo. The forkhead associated domain of MSP58 is essential for its interaction with Ndrg2. Ndrg2 could co-localize with MSP58 in nuclear of HeLa cell during cell stress. Furthermore, the modulation of Ndrg2 level influences the cell cycle process together with MSP58. In conclusion, the findings offered a novel insight into the physiological roles of Ndrg2

  7. Science Innovation Through Industry Partnership: Lessons from AMPERE in Bridging the Federal Sponsor/Private Corporation Divide (United States)

    Anderson, B. J.; Korth, H.; Erlandson, R. E.


    services. More general differences in the federal procurement timeline versus the corporate decision making timeline were also encountered. These lessons in the industry/federal partnership for innovative science are discussed as they may offer guidance for future efforts.

  8. Initiating New Science Partnerships in Rural Education (INSPIRE) Brining STEM Research to 7th-12th Grade Science and Math Classrooms (United States)

    Radencic, S.; McNeal, K. S.; Pierce, D.


    The Initiating New Science Partnerships in Rural Education (INSPIRE) program at Mississippi State University (MSU), funded by the NSF Graduate STEM Fellows in K-12 Education (GK12) program, focuses on the advancement of Earth and Space science education in K-12 classrooms. INSPIRE currently in its third year of partnering ten graduate students each year from the STEM fields of Geosciences, Engineering, Physics and Chemistry at MSU with five teachers from local, rural school districts. The five year project serves to enhance graduate student's communication skills as they create interactive lessons linking their STEM research focus to the state and national standards covered in science and math classrooms for grades 7-12 through inquiry experiences. Each graduate student is responsible for the development of two lessons each month of the school year that include an aspect of their STEM research, including the technologies that they may utilize to conduct their STEM research. The plans are then published on the INSPIRE project webpage,, where they are a free resource for any K-12 classroom teacher seeking innovative activities for their classrooms and total over 300 lesson activities to date. Many of the participating teachers and graduate students share activities developed with non-participating teachers, expanding INSPIRE's outreach of incorporating STEM research into activities for K-12 students throughout the local community. Examples of STEM research connections to classroom topics related to earth and ocean science include activities using GPS with GIS for triangulation and measurement of area in geometry; biogeochemical response to oil spills compared to organism digestive system; hydrogeology water quality monitoring and GIS images used as a determinant for habitat suitability in area water; interactions of acids and bases in the Earth's environments and surfaces; and the importance of electrical circuitry in an electrode used in

  9. Efficacy development in science: Investigating the effects of the Teacher-to-Teacher (T2T) professional development model in Hilo elementary schools (United States)

    Pinner, Pascale Creek

    Conderman and Sheldon Woods (2008) suggest that although science plays a central role in our world today, science instruction seems to be minimized particularly at the elementary grade levels. Research has investigated the construct of efficacy (Bandura, 1977, 2006a; Riggs & Enochs, 1990; Ramey-Gassert, Shroyer & Staver, 1996; Tschannen-Moran, Hoy & Hoy, 1998, 2001). Professional and conceptual development in teachers has also been explored (Gordon, 1990; Sheerer, 1997; Skaalvik & Skaalvik, 2007). The purpose of this research was to describe the changes in efficacy elementary teachers experience as they participated in science professional development. Data from a Math/Science Partnership (MSP) grant sample suggested significant changes in science self-efficacy and improved pedagogy. Mixed methods revealed connections resulting in a multi-faceted Progression of Efficacy Growth flowchart. The results suggest that utilizing the Teacher-to-Teacher (T2T) professional development model has created a pathway for more science teaching across the Hilo elementary schools.

  10. Characterization of AlgMsp, an alginate lyase from Microbulbifer sp. 6532A.

    Directory of Open Access Journals (Sweden)

    Steven M Swift

    Full Text Available Alginate is a polysaccharide produced by certain seaweeds and bacteria that consists of mannuronic acid and guluronic acid residues. Seaweed alginate is used in food and industrial chemical processes, while the biosynthesis of bacterial alginate is associated with pathogenic Pseudomonas aeruginosa. Alginate lyases cleave this polysaccharide into short oligo-uronates and thus have the potential to be utilized for both industrial and medicinal applications. An alginate lyase gene, algMsp, from Microbulbifer sp. 6532A, was synthesized as an E.coli codon-optimized clone. The resulting 37 kDa recombinant protein, AlgMsp, was expressed, purified and characterized. The alginate lyase displayed highest activity at pH 8 and 0.2 M NaCl. Activity of the alginate lyase was greatest at 50°C; however the enzyme was not stable over time when incubated at 50°C. The alginate lyase was still highly active at 25°C and displayed little or no loss of activity after 24 hours at 25°C. The activity of AlgMsp was not dependent on the presence of divalent cations. Comparing activity of the lyase against polymannuronic acid and polyguluronic acid substrates showed a higher turnover rate for polymannuronic acid. However, AlgMSP exhibited greater catalytic efficiency with the polyguluronic acid substrate. Prolonged AlgMsp-mediated degradation of alginate produced dimer, trimer, tetramer, and pentamer oligo-uronates.

  11. Twenty-first Century Space Science in The Urban High School Setting: The NASA/John Dewey High School Educational Outreach Partnership (United States)

    Fried, B.; Levy, M.; Reyes, C.; Austin, S.


    A unique and innovative partnership has recently developed between NASA and John Dewey High School, infusing Space Science into the curriculum. This partnership builds on an existing relationship with MUSPIN/NASA and their regional center at the City University of New York based at Medgar Evers College. As an outgrowth of the success and popularity of our Remote Sensing Research Program, sponsored by the New York State Committee for the Advancement of Technology Education (NYSCATE), and the National Science Foundation and stimulated by MUSPIN-based faculty development workshops, our science department has branched out in a new direction - the establishment of a Space Science Academy. John Dewey High School, located in Brooklyn, New York, is an innovative inner city public school with students of a diverse multi-ethnic population and a variety of economic backgrounds. Students were recruited from this broad spectrum, which covers the range of learning styles and academic achievement. This collaboration includes students of high, average, and below average academic levels, emphasizing participation of students with learning disabilities. In this classroom without walls, students apply the strategies and methodologies of problem-based learning in solving complicated tasks. The cooperative learning approach simulates the NASA method of problem solving, as students work in teams, share research and results. Students learn to recognize the complexity of certain tasks as they apply Earth Science, Mathematics, Physics, Technology and Engineering to design solutions. Their path very much follows the NASA model as they design and build various devices. Our Space Science curriculum presently consists of a one-year sequence of elective classes taken in conjunction with Regents-level science classes. This sequence consists of Remote Sensing, Planetology, Mission to Mars (NASA sponsored research program), and Microbiology, where future projects will be astronomy related. This

  12. Models of Interinstitutional Partnerships between Research Intensive Universities and Minority Serving Institutions (MSI) across the Clinical Translational Science Award (CTSA) Consortium (United States)

    Fair, Alecia; Norris, Keith; Verbalis, Joseph G.; Poland, Russell; Bernard, Gordon; Stephens, David S.; Dubinett, Steven M.; Imperato‐McGinley, Julianne; Dottin, Robert P.; Pulley, Jill; West, Andrew; Brown, Arleen; Mellman, Thomas A.


    Abstract Health disparities are an immense challenge to American society. Clinical and Translational Science Awards (CTSAs) housed within the National Center for Advancing Translational Science (NCATS) are designed to accelerate the translation of experimental findings into clinically meaningful practices and bring new therapies to the doorsteps of all patients. Research Centers at Minority Institutions (RCMI) program at the National Institute on Minority Health and Health Disparities (NIMHD) are designed to build capacity for biomedical research and training at minority serving institutions. The CTSA created a mechanism fostering formal collaborations between research intensive universities and minority serving institutions (MSI) supported by the RCMI program. These consortium‐level collaborations activate unique translational research approaches to reduce health disparities with credence to each academic institutions history and unique characteristics. Five formal partnerships between research intensive universities and MSI have formed as a result of the CTSA and RCMI programs. These partnerships present a multifocal approach; shifting cultural change and consciousness toward addressing health disparities, and training the next generation of minority scientists. This collaborative model is based on the respective strengths and contributions of the partnering institutions, allowing bidirectional interchange and leveraging NIH and institutional investments providing measurable benchmarks toward the elimination of health disparities. PMID:24119157

  13. Interactions of rat repetitive sequence MspI8 with nuclear matrix proteins during spermatogenesis

    International Nuclear Information System (INIS)

    Rogolinski, J.; Widlak, P.; Rzeszowska-Wolny, J.


    Using the Southwestern blot analysis we have studied the interactions between rat repetitive sequence MspI8 and the nuclear matrix proteins of rats testis cells. Starting from 2 weeks the young to adult animal showed differences in type of testis nuclear matrix proteins recognizing the MspI8 sequence. The same sets of nuclear matrix proteins were detected in some enriched in spermatocytes and spermatids and obtained after fractionation of cells of adult animal by the velocity sedimentation technique. (author). 21 refs, 5 figs

  14. Genome sequencing and annotation of Acinetobacter guillouiae strain MSP 4-18

    Directory of Open Access Journals (Sweden)

    Nitin Kumar Singh


    Full Text Available The genus Acinetobacter consists of 31 validly published species ubiquitously distributed in nature and primarily associated with nosocomial infection. We report the 4.8 Mb genome of Acinetobacter guillouiae MSP 4-18, isolated from a mangrove soil sample from Parangipettai (11°30′N, 79°47′E, Tamil Nadu, India. The draft genome of A. guillouiae MSP 4-18 has a G + C content of 38.0% and includes 3 rRNA genes (5S, 23S, 16S and 69 aminoacyl-tRNA synthetase genes.

  15. Some partnership

    International Nuclear Information System (INIS)

    Stein, Graham.


    The nuclear industry claims that it wants a partnership with renewable energy as part of a balanced energy programme. The author looks at information on renewables supplied by the nuclear industry and finds it economical with the truth. (author)

  16. A collection of research reporting, theoretical analysis, and practical applications in science education: Examining qualitative research methods, action research, educator-researcher partnerships, and constructivist learning theory (United States)

    Hartle, R. Todd


    Educator-researcher partnerships are increasingly being used to improve the teaching of science. Chapter 1 provides a summary of the literature concerning partnerships, and examines the justification of qualitative methods in studying these relationships. It also justifies the use of Participatory Action Research (PAR). Empirically-based studies of educator-researcher partnership relationships are rare despite investments in their implementation by the National Science Foundation (NSF) and others. Chapter 2 describes a qualitative research project in which participants in an NSF GK-12 fellowship program were studied using informal observations, focus groups, personal interviews, and journals to identify and characterize the cultural factors that influenced the relationships between the educators and researchers. These factors were organized into ten critical axes encompassing a range of attitudes, behaviors, or values defined by two stereotypical extremes. These axes were: (1) Task Dictates Context vs. Context Dictates Task; (2) Introspection vs. Extroversion; (3) Internal vs. External Source of Success; (4) Prior Planning vs. Implementation Flexibility; (5) Flexible vs. Rigid Time Sense; (6) Focused Time vs. Multi-tasking; (7) Specific Details vs. General Ideas; (8) Critical Feedback vs. Encouragement; (9) Short Procedural vs. Long Content Repetition; and (10) Methods vs. Outcomes are Well Defined. Another ten important stereotypical characteristics, which did not fit the structure of an axis, were identified and characterized. The educator stereotypes were: (1) Rapport/Empathy; (2) Like Kids; (3) People Management; (4) Communication Skills; and (5) Entertaining. The researcher stereotypes were: (1) Community Collaboration; (2) Focus Intensity; (3) Persistent; (4) Pattern Seekers; and (5) Curiosity/Skeptical. Chapter 3 summarizes the research presented in chapter 2 into a practical guide for participants and administrators of educator-researcher partnerships

  17. Middlesex Sampling Plant [MSP] annual site environmental report, calendar year 1988

    International Nuclear Information System (INIS)


    The environmental monitoring program, which began in 1980, was continued in 1988 at the former Middlesex Sampling Plant (MSP) site, located in the Borough of Middlesex, New Jersey. The MSP site is part of the Formerly Utilized Site Remedial Action Program (FUSRAP), a Department of Energy (DOE) program to decontaminate or otherwise control sites where residual radioactive materials remain either from the early years of the nation's atomic energy program or from commercial operations causing conditions that Congress has mandated DOE to remedy. The environmental monitoring program is carried out by Bechtel National, Inc. (BNI), project management contractor for FUSRAP. The monitoring program at the MSP measures radon concentrations in air; external gamma radiation levels; and uranium and radium concentrations in surface water, groundwater, and sediment. To verify that the site is in compliance with the DOE radiation protection standard (100 mrem/yr) and to assess its potential effect on public health, the radiation dose was calculated for a hypothetical maximally exposed individual. Results of the 1988 monitoring show that the MSP is in compliance with applicable DOE radiation protection standards and with applicable requirements specified by New Jersey Department of Environmental Protection groundwater permits. 17 refs., 15 figs., 21 tabs

  18. Diversity of ankA and msp4 genes of Anaplasma phagocytophilum in Slovenia. (United States)

    Strašek Smrdel, Katja; von Loewenich, Friederike D; Petrovec, Miroslav; Avšič Županc, Tatjana


    Granulocytic anaplasmosis is a tick transmitted emerging disease in Europe and worldwide. The agent, Anaplasma phagocytophilum is transmitted by ticks of the genus Ixodes and causes infections in humans and domestic animals. The analysis of different target genes showed that in nature several genetic variants of A. phagocytophilum were present. The purpose of our study was to genetically characterize A. phagocytophilum strains from eight humans, 16 dogs, 12 wild boars, one bear and 18 tick pools from Slovenia. Therefore, the ankA and msp4 genes of A. phagocytophilum were chosen. The same genetic ankA and msp4 variant of A. phagocytophilum was detected in humans, wild boar and a part of the pooled ticks indicating that it circulates in a zoonotic cycle between wild boar and ticks. In dogs, three ankA variants of A. phagocytophilum were detected. One of them was identical to the one that was found in humans. In contrast, all dogs harboured the same msp4 variant as humans and wild boar. In ticks, numerous ankA and msp4 variants were present. Copyright © 2014 Elsevier GmbH. All rights reserved.

  19. MSP-tool : A VBA-based software tool for the analysis of multispecimen paleointensity data

    NARCIS (Netherlands)

    Monster, Marilyn W L; de Groot, Lennart V.; Dekkers, Mark J.


    The multispecimen protocol (MSP) is a method to estimate the Earth's magnetic field's past strength from volcanic rocks or archeological materials. By reducing the amount of heating steps and aligning the specimens parallel to the applied field, thermochemical alteration and multi-domain effects are

  20. Antigenic variation of Anaplasma marginale msp2 occurs by combinatorial gene conversion. (United States)

    Brayton, Kelly A; Palmer, Guy H; Lundgren, Anna; Yi, Jooyoung; Barbet, Anthony F


    The rickettsial pathogen Anaplasma marginale establishes lifelong persistent infection in the mammalian reservoir host, during which time immune escape variants continually arise in part because of variation in the expressed copy of the immunodominant outer membrane protein MSP2. A key question is how the small 1.2 Mb A. marginale genome generates sufficient variants to allow long-term persistence in an immunocompetent reservoir host. The recombination of whole pseudogenes into the single msp2 expression site has been previously identified as one method of generating variants, but is inadequate to generate the number of variants required for persistent infection. In the present study, we demonstrate that recombination of a whole pseudogene is followed by a second level of variation in which small segments of pseudogenes recombine into the expression site by gene conversion. Evidence for four short sequential changes in the hypervariable region of msp2 coupled with the identification of nine pseudogenes from a single strain of A. marginale provides for a combinatorial number of possible expressed MSP2 variants sufficient for lifelong persistence.

  1. NASA Space Science Days: An Out of School Program Using National Partnerships to Further Influence Future Scientists and Engineers. (United States)

    Galindo, Charles; Allen, Jaclyn; Garcia, Javier; Hrrera, Stephanie


    The National Math and Science Initiative states that American students are falling behind in the essential subjects of math and science, putting our position in the global economy at risk a foreboding statement that has caused the U.S. to re-evaluate how we view STEM education. Developing science and engineering related out of school programs that expose middle school students to math and science in a nontraditional university environment has the potential to motivate young students to look at the physical sciences in an exciting out of the norm environment.

  2. Utilizing Local Partnerships to Enhance Workforce Development (United States)

    Whikehart, John


    The Indiana Center for the Life Sciences, an award-winning partnership between education, government, and the private sector, houses state-of-the-art science labs, classrooms, and industry training space for community college students and local employers. This innovative partnership prepares both the current and future workforce for careers in the…

  3. Global phylogeography of the avian malaria pathogen Plasmodium relictum based on MSP1 allelic diversity (United States)

    Hellgren, Olof; Atkinson, Carter T.; Bensch, Staffan; Albayrak, Tamer; Dimitrov, Dimitar; Ewen, John G.; Kim, Kyeong Soon; Lima, Marcos R.; Martin, Lynn; Palinauskas, Vaidas; Ricklefs, Robert; Sehgal, Ravinder N. M.; Gediminas, Valkiunas; Tsuda, Yoshio; Marzal, Alfonso


    Knowing the genetic variation that occurs in pathogen populations and how it is distributed across geographical areas is essential to understand parasite epidemiology, local patterns of virulence, and evolution of host-resistance. In addition, it is important to identify populations of pathogens that are evolutionarily independent and thus ‘free’ to adapt to hosts and environments. Here, we investigated genetic variation in the globally distributed, highly invasive avian malaria parasite Plasmodium relictum, which has several distinctive mitochondrial haplotyps (cyt b lineages, SGS1, GRW11 and GRW4). The phylogeography of P. relictum was accessed using the highly variable nuclear gene merozoite surface protein 1 (MSP1), a gene linked to the invasion biology of the parasite. We show that the lineage GRW4 is evolutionarily independent of GRW11 and SGS1 whereas GRW11 and SGS1 share MSP1 alleles and thus suggesting the presence of two distinct species (GRW4 versus SGS1 and GRW11). Further, there were significant differences in the global distribution of MSP1 alleles with differences between GRW4 alleles in the New and the Old World. For SGS1, a lineage formerly believed to have both tropical and temperate transmission, there were clear differences in MSP1 alleles transmitted in tropical Africa compared to the temperate regions of Europe and Asia. Further, we highlight the occurrence of multiple MSP1 alleles in GRW4 isolates from the Hawaiian Islands, where the parasite has contributed to declines and extinctions of endemic forest birds since it was introduced. This study stresses the importance of multiple independent loci for understanding patterns of transmission and evolutionary independence across avian malaria parasites.

  4. Revitalising Evidence-based Policy for the Sendai Framework for Disaster Risk Reduction 2015-2030: Lessons from Existing International Science Partnerships. (United States)

    Carabine, Elizabeth


    The convergence of agreements on disaster risk reduction (DRR), development finance, sustainable development and climate change in 2015 presents a unique opportunity for coherence across these inter-related policy areas. At the same time, demand is growing for a more prominent and effective role for science and technology in providing evidence for policy, with the international community recognising that successful disaster risk reduction (DRR) depends on it. Reflecting this ambition, science is included as a core aspect of the Sendai Framework for Disaster Risk Reduction 2015-2030, although the ways in which this will be implemented in practice is still unclear. This paper aims to inform the implementation of international science coordination for DRR by examining a number of existing international science partnerships used across other relevant areas of policy to understand best practice, options for coordination and lessons identified. In the field of DRR, the science-policy interface needs to be strengthened in line with the best practice described in this review. An enhanced UNISDR Scientific and Technical Advisory Group will be given the mandate for to enhance the evidence base for DRR and mobilise science and technical work in coordination with a broad range of stakeholders. The structure and function of an enhanced STAG must be as open, as inclusive and as participatory as possible in order to build trust in new and existing institutions at local, national, regional and global levels. The challenge for the international community is to facilitate evidence-based policy making by formally recognising the links between DRR, development finance, sustainable development and climate change in the upcoming post-2015 agreements.

  5. Toward Understanding the Nature of a Partnership between an Elementary Classroom Teacher and an Informal Science Educator (United States)

    Weiland, Ingrid S.; Akerson, Valarie L.


    This study explored the nature of the relationship between a fifth-grade teacher and an informal science educator as they planned and implemented a life science unit in the classroom, and sought to define this relationship in order to gain insight into the roles of each educator. In addition, student learning as a result of instruction was…

  6. Prospects for Policy Advances in Science and Technology in the Gulf Arab States: "The Role for International Partnerships" (United States)

    Hajjar, David P.; Moran, George W.; Siddiqi, Afreen; Richardson, Joshua E.; Anadon, Laura D.; Narayanamurti, Venkatesh


    Science, technology, engineering and mathematics (STEM) policies in the Gulf Arab States are as diverse as the individual economies and political processes that characterize its member states. During the past decade, a number of expert review groups have argued that science and technology policy needs to be reformed and revitalized in the Gulf…


    Hauptmann, Emily


    The Carnegie Corporation's role as a patron of the behavioral sciences has been overlooked; its support for the behavioral sciences not only began earlier than the Ford Foundation's but was also at least equally important to their success. I show how the close postwar collaboration between the Carnegie Corporation and the Social Science Research Council (SSRC) to promote the behavioral sciences emerged after a struggle between Carnegie and the Rockefeller Foundation over the direction and leadership of the SSRC. I then focus on three postwar projects Carnegie helped conceive and fund that were publicized as the work of the SSRC: Chase's The Proper Study of Mankind (1948), Stouffer et al.'s The American Soldier (), and the Michigan's Survey Research Center 1952 election study. In each of these projects, Carnegie deliberately muted its own role and promoted the remade SSRC as a major advocate for the behavioral sciences. © 2016 Wiley Periodicals, Inc.

  8. Cellular responses to modified Plasmodium falciparum MSP119 antigens in individuals previously exposed to natural malaria infection

    Directory of Open Access Journals (Sweden)

    Awobode Henrietta O


    Full Text Available Abstract Background MSP1 processing-inhibitory antibodies bind to epitopes on the 19 kDa C-terminal region of the Plasmodium falciparum merozoite surface protein 1 (MSP119, inhibiting erythrocyte invasion. Blocking antibodies also bind to this antigen but prevent inhibitory antibodies binding, allowing invasion to proceed. Recombinant MSP119 had been modified previously to allow inhibitory but not blocking antibodies to continue to bind. Immunization with these modified proteins, therefore, has the potential to induce more effective protective antibodies. However, it was unclear whether the modification of MSP119 would affect critical T-cell responses to epitopes in this antigen. Methods The cellular responses to wild-type MSP119 and a panel of modified MSP119 antigens were measured using an in-vitro assay for two groups of individuals: the first were malaria-naïve and the second had been naturally exposed to Plasmodium falciparum infection. The cellular responses to the modified proteins were examined using cells from malaria-exposed infants and adults. Results Interestingly, stimulation indices (SI for responses induced by some of the modified proteins were at least two-fold higher than those elicited by the wild-type MSP119. A protein with four amino acid substitutions (Glu27→Tyr, Leu31→Arg, Tyr34→Ser and Glu43→Leu had the highest stimulation index (SI up to 360 and induced large responses in 64% of the samples that had significant cellular responses to the modified proteins. Conclusion This study suggests that specific MSP119 variants that have been engineered to improve their antigenicity for inhibitory antibodies, retain T-cell epitopes and the ability to induce cellular responses. These proteins are candidates for the development of MSP1-based malaria vaccines.

  9. Broadly reactive antibodies specific for Plasmodium falciparum MSP-119 are associated with the protection of naturally exposed children against infection

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    Dent Arlene E


    Full Text Available Abstract Background The 19 kDa C-terminal region of Plasmodium falciparum Merozoite Surface Protein-1 is a known target of naturally acquired humoral immunity and a malaria vaccine candidate. MSP-119 has four predominant haplotypes resulting in amino acid changes labelled EKNG, QKNG, QTSR and ETSR. IgG antibodies directed against all four variants have been detected, but it is not known if these variant specific antibodies are associated with haplotype-specific protection from infection. Methods Blood samples from 201 healthy Kenyan adults and children who participated in a 12-week treatment time-to-infection study were evaluated. Venous blood drawn at baseline (week 0 was examined for functional and serologic antibodies to MSP-119 and MSP-142 variants. MSP-119 haplotypes were detected by a multiplex PCR assay at baseline and weekly throughout the study. Generalized linear models controlling for age, baseline MSP-119 haplotype and parasite density were used to determine the relationship between infecting P. falciparum MSP-119 haplotype and variant-specific antibodies. Results A total of 964 infections resulting in 1,533 MSP-119 haplotypes detected were examined. The most common haplotypes were EKNG and QKNG, followed by ETSR and QTSR. Children had higher parasite densities, greater complexity of infection (>1 haplotype, and more frequent changes in haplotypes over time compared to adults. Infecting MSP-119 haplotype at baseline (week 0 had no influence on haplotypes detected over the subsequent 11 weeks among children or adults. Children but not adults with MSP-119 and some MSP-142 variant antibodies detected by serology at baseline had delayed time-to-infection. There was no significant association of variant-specific serology or functional antibodies at baseline with infecting haplotype at baseline or during 11 weeks of follow up among children or adults. Conclusions Variant transcending IgG antibodies to MSP-119 are associated with protection

  10. Expression of recombinant myostatin propeptide pPIC9K-Msp plasmid in Pichia pastoris. (United States)

    Du, W; Xia, J; Zhang, Y; Liu, M J; Li, H B; Yan, X M; Zhang, J S; Li, N; Zhou, Z Y; Xie, W Z


    Myostatin propeptide can inhibit the biological activity of myostatin protein and promote muscle growth. To express myostatin propeptide in vitro with a higher biological activity, we performed codon optimization on the sheep myostatin propeptide gene sequence, and mutated aspartic acid-76 to alanine based on the codon usage bias of Pichia pastoris and the enhanced biological activity of myostatin propeptide mutant. Modified myostatin propeptide gene was cloned into the pPIC9K plasmid to form the recombinant plasmid pPIC9K-Msp. Recombinant plasmid pPIC9K-Msp was transformed into Pichia pastoris GS115 by electrotransformation. Transformed cells were screened, and methanol was used to induce expression. SDS-PAGE and western blotting were used to verify the successful expression of myostatin propeptide with biological activity in Pichia pastoris, providing the basis for characterization of this protein.


    Directory of Open Access Journals (Sweden)

    Thang Vu Chien


    Full Text Available Wireless Sensor Networks (WSNs consist of a large number of sensor nodes, and are used for various applications such as building monitoring, environment control, wild-life habitat monitoring, forest fire detection, industry automation, military, security, and health-care. Each sensor node needs an operating system (OS that can control the hardware, provide hardware abstraction to application software, and fill in the gap between applications and the underlying hardware. In this paper, researchers present OS for WSNs and an experiment of porting contikiOS to MSP430 microcontroller which is very popular in many hardware platforms for WSNs. Researchers begin by presenting the major issues for the design of OS for WSNs. Then, researchers examine some popular operating systems for WSNs including TinyOS, ContikiOS, and LiteOS. Finally, researchers present an experiment of porting ContikiOS to MSP430 microcontroller. Wireless Sensor Networks (WSNs terdiri dari sejumlah besar sensor nodes, dan digunakan untuk berbagai aplikasi seperti pemantauan gedung, pengendalian lingkungan, pemantauan kehidupan habitat liar, deteksi kebakaran hutan, otomatisasi industri, militer, keamanan, dan kesehatan. Setiap sensor nodememerlukan sistem operasi (SO yang dapat mengontrol hardware, menyediakan abstraksi hardware untuk aplikasi perangkat lunak, dan mengisi kesenjangan antara aplikasi dan hardware. Dalam penelitian ini, peneliti menyajikan SO untuk WSNs dan percobaan dari port contikiOS untuk MSP430 mikrokontroler yang sangat populer di platformhardware untuk WSNs. Peneliti memulai dengan menghadirkan isu utama yaitu desain SO untuk WSNs. Lalu, penelitimemeriksa beberapa sistem operasi populer untuk WSNs, termasuk TinyOS, ContikiOS, dan LiteOS. Akhirnya penelitimenyajikan sebuah percobaan dari port ContikiOS untuk MSP430 mikrokontroler.

  12. Multiple-specimen absolute paleointensity determination with the MSP-DSC protocol: Advantages and drawbacks. (United States)

    Camps, P.; Fanjat, G.; Poidras, T.; Carvallo, C.; Nicol, P.


    The MSP-DSC protocol (Dekkers & Bohnel, 2006, EPSL; Fabian & Leonhardt, 2010, EPSL) is a recent development in the methodology for documenting the intensity of the ancient Earth magnetic field. Applicable both on rocks or archaeological artifacts it allows us to use samples that until now were not measured because their magnetic properties do not meet selection criteria required by conventional methods. However, this new experimental protocol requires that samples be heated and cooled under a field parallel to its natural remanent magnetization (NRM). Currently, standard paleointensity furnaces do not match precisely this constraint. Yet, such new measurement protocol seems very promising since it would possibly double the number of available data. We are developing in Montpellier (France), a very fast-heating oven with infrared dedicated to this protocol. Two key points determine its characteristics. The first is to heat uniformly a rock sample of a 10-cc-standard volume as fast as possible. The second is to apply to the sample during the heating (and the cooling) a precise magnetic induction field, perfectly controlled in 3D. We tested and calibrated a preliminary version of this oven along with the MSP-DSC protocol with 3 historical lava flows, 2 from Reunion Island (erupted in 2002 and 2007) and one from Etna (erupted in 1983). These lava flows were selected because they have different magnetic behaviors. Reunion 2002 is rather SD-PSD-like, while Reunion 2007 is PSD-MD-like, and Etna 1983 is MD-like. The paleointensity determinations obtained with the original protocol of Dekkers and Bohnel (2006, EPSL) are within +- 1 μT of the known field for the three lava flows. The same precision is obtained when we applied the fraction correction (MSP-FC protocol). However, we systematically observed a loss in the linearity of the MSP-FC plots. In addition, like Muxworthy and Taylor (2011, GJI), we found that the Domain State Correction is difficult to apply since alpha

  13. Facing climate change in forests and fields: U.S. Forest Service taps into science-management partnerships (United States)

    Amy Daniels; Nancy Shaw; Dave Peterson; Keith Nislow; Monica Tomosy; Mary Rowland


    As a growing body of science shows, climate change impacts on wildlife are already profound—from shifting species’ ranges and altering the synchronicity of food sources to changing the availability of water. Such impacts are only expected to increase in the coming decades. As climate change shapes complex, interwoven ecological processes, novel conditions and...

  14. Science Teachers' Views and Stereotypes of Religion, Scientists and Scientific Research: A Call for Scientist-Science Teacher Partnerships to Promote Inquiry-Based Learning (United States)

    Mansour, Nasser


    Despite a growing consensus regarding the value of inquiry-based learning (IBL) for students' learning and engagement in the science classroom, the implementation of such practices continues to be a challenge. If science teachers are to use IBL to develop students' inquiry practices and encourage them to think and act as scientists, a better…

  15. Anaplasma phagocytophilum MSP4 and HSP70 Proteins Are Involved in Interactions with Host Cells during Pathogen Infection

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    Marinela Contreras


    Full Text Available Anaplasma phagocytophilum transmembrane and surface proteins play a role during infection and multiplication in host neutrophils and tick vector cells. Recently, A. phagocytophilum Major surface protein 4 (MSP4 and Heat shock protein 70 (HSP70 were shown to be localized on the bacterial membrane, with a possible role during pathogen infection in ticks. In this study, we hypothesized that A. phagocytophilum MSP4 and HSP70 have similar functions in tick-pathogen and host-pathogen interactions. To address this hypothesis, herein we characterized the role of these bacterial proteins in interaction and infection of vertebrate host cells. The results showed that A. phagocytophilum MSP4 and HSP70 are involved in host-pathogen interactions, with a role for HSP70 during pathogen infection. The analysis of the potential protective capacity of MSP4 and MSP4-HSP70 antigens in immunized sheep showed that MSP4-HSP70 was only partially protective against pathogen infection. This limited protection may be associated with several factors, including the recognition of non-protective epitopes by IgG in immunized lambs. Nevertheless, these antigens may be combined with other candidate protective antigens for the development of vaccines for the control of human and animal granulocytic anaplasmosis. Focusing on the characterization of host protective immune mechanisms and protein-protein interactions at the host-pathogen interface may lead to the discovery and design of new effective protective antigens.

  16. Using 'Ozzie the Ostrich' to Build Local Partnerships around Climate Change Learning (United States)

    Lustick, D. S.; Lohmeier, J.; Chen, R. F.; Wilson, R.; Rabkin, D.; Thompson, S. R.


    How can an informal science learning project about climate change facilitate alliances among unlikely parties? We found a sweet spot of collaboration among private, public, and the non-profit sectors by borrowing strength and leveraging common interests. Using mass transit and out of home media, we created a diverse community around a learning campaign that starred an ostrich named "Ozzie." In 2013-14, ran a series of 12 engaging posters and placards staring 'Ozzie the Ostrich' on the Massachusetts Bay Transit Authority's Red and Orange subway lines targeting a daily audience of 400,000+ riders. The curriculum was divided into three phases: reality, relevance, and hope. Phase I established the reality of climate change (3 months). Phase II helped T-riders appreciate the relevancy of climate change to the local environment of Boston (4 months). Phase III engaged Bostonians with an array of hopeful examples of how people, companies, and organizations are effectively creating a more sustainable future (5 months). The focus of this presentation will be on the relationships that emerged from the work that went into Phase III. Engaging urban populations with climate change science is a difficult challenge since cities seem so removed from the 'natural environment.' However, mass transit provides an inherent means of communicating environmental messages with a cross section of the urban population. Our team felt that any messaging curriculum for an urban subway system must complement the scary reality of a changing climate with hopeful solutions that exist for dealing with it effectively. Urban areas such as Boston must develop adaptation and mitigation strategies that will help them not only survive, but thrive in a changing environment. Making our audience aware of the amazing efforts in this area was the goal of Phase III. There were three parts to our efforts: the signage on the subway, above ground ostriches, and social events. During the presentation

  17. Toward actionable science: Empowering ecologists to engage in the process of translation through decision-maker and stakeholder partnerships (United States)

    Enquist, C.; Jackson, S. T.; Garfin, G. M.


    Translational ecology is an approach by which ecologists, stakeholders, and decision-makers work collaboratively to develop and deliver ecological research that, ideally, results in actionable science that leads to improved environmental decision-making. We analyzed a diverse array of real-world case studies and distilled six principles that characterize the practice of translational ecology: communication, commitment, collaboration, engagement, process, and decision-framing. In this talk, we highlight a subset of the case studies that illustrate these principles. Notably, we found that translational ecology is distinct from both basic and applied ecological research. As a practice, the approach deliberately extends research beyond theory or opportunistic applications, motivated by a search for outcomes that directly serve the needs of natural resource managers and decision-makers. Translational ecology is also distinct from knowledge co-production in that it does not require deep engagement between collaborators, although incorporating differing modes of co-production relative to the decision context, associated time frame, and available financial resources can greatly enhance the translational approach. Although there is a need for incentives to pursue in this type of work, we found that the creativity and context-specific knowledge of resource managers, practitioners, and decision-makers informs and enriches the scientific process, helping shape actionable science. Moreover, the process of addressing research questions arising from on-the-ground management issues, rather than from the top-down or expert-oriented perspectives of traditional science, can foster the long-term trust and commitment that is critical for long-term, sustained engagement between partners. Now, perhaps more than ever, the climate and environmental issues facing society are complex, often politicized, and value-laden. We argue that ecological science should play a key role in informing

  18. Technology Partnership Agreements | NREL (United States)

    Partnership Agreements Technology Partnership Agreements Looking for Funding? We do not fund any projects under a technology partnership agreement. The partner provides the necessary resources and, in using technology partnership agreements. See a summary of our Fiscal Year 2017 technology partnership

  19. Integrating Science-Based Co-management, Partnerships, Participatory Processes and Stewardship Incentives to Improve the Performance of Small-Scale Fisheries

    Directory of Open Access Journals (Sweden)

    Kendra A. Karr


    Full Text Available Small scale fisheries are critically important for the provision of food security, livelihoods, and economic development for billions of people. Yet, most of these fisheries appear to not be achieving either fisheries or conservation goals, with respect to creating healthier oceans that support more fish, feed more people and improve livelihoods. Research and practical experience have elucidated many insights into how to improve the performance of small-scale fisheries. Here, we present lessons learned from five case studies of small-scale fisheries in Cuba, Mexico, the Philippines, and Belize. The major lessons that arise from these cases are: (1 participatory processes empower fishers, increase compliance, and support integration of local and scientific knowledge; (2 partnership across sectors improves communication and community buy-in; (3 scientific analysis can lead fishery reform and be directly applicable to co-management structures. These case studies suggest that a fully integrated approach that implements a participatory process to generate a scientific basis for fishery management (e.g., data collection, analysis, design and to design management measures among stakeholders will increase the probability that small-scale fisheries will implement science-based management and improve their performance.

  20. Evaluating the Impact of the Medical Education Partnership Initiative at the University of Zimbabwe College of Health Sciences Using the Most Significant Change Technique. (United States)

    Connors, Susan C; Nyaude, Shemiah; Challender, Amelia; Aagaard, Eva; Velez, Christine; Hakim, James


    In medical education, evaluating outcomes from programs intended to transform attitudes or influence career trajectories using conventional methods of monitoring is often difficult. To address this problem, the authors adapted the most significant change (MSC) technique to gain a more comprehensive understanding of the impact of the Medical Education Partnership Initiative (MEPI) program at the University of Zimbabwe College of Health Sciences. In 2014-2015, the authors applied the MSC to systematically examine the personal significance and level of positive transformation that individuals attributed to their MEPI participation. Interviews were conducted with 28 participants nominated by program leaders. The authors coded results inductively for prevalent themes in participants' stories and prepared profiles with representative quotes to place the stories in context. Stakeholders selected 9 themes and 18 stories to illustrate the most significant changes. Six themes (or outcomes) were expected, as they aligned with MEPI goals-becoming a better teacher, becoming a better clinician, increased interest in teaching, increased interest in research, new career pathways (including commitment to practice in Zimbabwe), and improved research skills. Three themes were unexpected-increased confidence, expanded interprofessional networks, and improved interpersonal interactions. The authors found the MSC to be a useful and systematic evaluation approach for large, complex, and transformative initiatives like MEPI. The MSC seemed to encourage participant reflection, support values inquiry by program leaders, and provide insights into the personal and cultural impacts of MEPI. Additional trial applications of the MSC technique in academic medicine are warranted.

  1. Sharing our successes II: Changing the face of science and mathematics education through teacher-focused partnerships

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    Industry Initiatives for Science and Math Education (IISME) in the San Francisco Bay Area planned and convened the second national conference for representatives of scientific work experience programs for K-12 teachers (SWEPs) at Lawrence Hall of Science, University of California at Berkeley October 13-14, 1994. The goal of this conference was to further strengthen the growing community of SWEP managers and teacher participants by providing an opportunity for sharing expertise and strategies about the following: (1) How SWEPs can complement and stimulate systemic education reform efforts; (2) Assessment strategies piloted by the ambitious multi-site evaluation project funded by the U.S. Department of Energy (DOE) as well as smaller evaluation projects piloted by other SWEPs; (3) Expanding and strengthening the base of teachers served by SWEPs; (4) Ensuring that SWEPs adequately support teachers in affecting classroom transfer and offer {open_quotes}more than just a summerjob{close_quotes}; (5) Sustaining and expanding new programs. A special teacher strand focused on leadership development supporting teachers to become effective change agents in their classrooms and schools, and developing strong teacher communities.

  2. Sociodemographic drivers of multiple sexual partnerships among women in three rural districts of Tanzania

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    Exavery A


    Full Text Available Amon Exavery,1 Almamy Malick Kanté,1–3 Kassimu Tani,1 Ahmed Hingora,1 James F Phillips2 1Ifakara Health Institute, Dar es Salaam, Tanzania; 2Heilbrunn Department of Population and Family Health, Mailman School of Public Health, Columbia University, New York, NY, USA; 3Swiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland Background: This study examines prevalence and correlates of multiple sexual partnerships (MSP among women aged 15+ years in Rufiji, Kilombero, and Ulanga districts of Tanzania. Materials and methods: Data were collected in a cross-sectional household survey in Rufiji, Kilombero, and Ulanga districts in Tanzania in 2011. From the survey, a total of 2,643 sexually active women ages 15+ years were selected for this analysis. While the chi-square test was used for testing association between MSP and each of the independent variables, logistic regression was used for multivariate analysis. Results: Number of sexual partners reported ranged from 1 to 7, with 7.8% of the women reporting multiple sexual partners (2+ in the past year. MSP was more likely among both ever married women (adjusted odds ratio [AOR] =3.83, 95% confidence interval [CI] 1.40–10.49 and single women (AOR =6.13, 95% CI 2.45–15.34 than currently married women. There was an interaction between marital status and education, whereby MSP was 85% less likely among single women with secondary or higher education compared to married women with no education (AOR =0.15, 95% CI 0.03–0.61. Furthermore, women aged 40+ years were 56% less likely compared to the youngest women (<20 years to report MSP (AOR =0.44, 95% CI 0.24–0.80. The odds of MSP among Muslim women was 1.56 times as high as that for Christians women (AOR =1.56, 95% CI 1.11–2.21. Ndengereko women were 67% less likely to report MSP compared to Pogoro women (AOR =0.33, 95% CI 0.18–0.59. Conclusion: Eight percent of the women aged 15+ in Rufiji, Kilombero, and Ulanga

  3. MGMT promoter methylation determined by HRM in comparison to MSP and pyrosequencing for predicting high-grade glioma response. (United States)

    Switzeny, Olivier J; Christmann, Markus; Renovanz, Mirjam; Giese, Alf; Sommer, Clemens; Kaina, Bernd


    The DNA repair protein O(6)-methylguanine-DNA methyltransferase (MGMT) causes resistance of cancer cells to alkylating agents and, therefore, is a well-established predictive marker for high-grade gliomas that are routinely treated with alkylating drugs. Since MGMT is highly epigenetically regulated, the MGMT promoter methylation status is taken as an indicator of MGMT silencing, predicting the outcome of glioma therapy. MGMT promoter methylation is usually determined by methylation specific PCR (MSP), which is a labor intensive and error-prone method often used semi-quantitatively. Searching for alternatives, we used closed-tube high resolution melt (HRM) analysis, which is a quantitative method, and compared it with MSP and pyrosequencing regarding its predictive value. We analyzed glioblastoma cell lines with known MGMT activity and formalin-fixed samples from IDH1 wild-type high-grade glioma patients (WHO grade III/IV) treated with radiation and temozolomide by HRM, MSP, and pyrosequencing. The data were compared as to progression-free survival (PFS) and overall survival (OS) of patients exhibiting the methylated and unmethylated MGMT status. A promoter methylation cut-off level relevant for PFS and OS was determined. In a multivariate Cox regression model, methylation of MGMT promoter of high-grade gliomas analyzed by HRM, but not MSP, was found to be an independent predictive marker for OS. Univariate Kaplan-Meier analyses revealed for PFS and OS a significant and better discrimination between methylated and unmethylated tumors when quantitative HRM was used instead of MSP. Compared to MSP and pyrosequencing, the HRM method is simple, cost effective, highly accurate and fast. HRM is at least equivalent to pyrosequencing in quantifying the methylation level. It is superior in predicting PFS and OS of high-grade glioma patients compared to MSP and, therefore, can be recommended being used routinely for determination of the MGMT status of gliomas.

  4. Lungworm seroprevalence in free-ranging harbour seals and molecular characterisation of marine mammal MSP

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    Sophia Arlena Ulrich


    Full Text Available Harbour seals (Phoca vitulina are frequently infected with the lungworms Otostrongylus circumlitus and Parafilaroides gymnurus. The infection is often accompanied by secondary bacterial infections and can cause severe bronchopneumonia and even death in affected animals. Hitherto, the detection of lungworm infections was based on post mortem investigations from animals collected within stranding networks and a valid detection method for live free-ranging harbour seals was not available. Recently, an ELISA was developed for detecting lungworm antibodies in harbour seal serum, using major sperm protein (MSP of the bovine lungworm, Dictyocaulus viviparus as recombinant diagnostic antigen. To determine lungworm seroprevalence in free-ranging harbour seals, serum was taken from four different seal age groups (n = 313 resulting in an overall prevalence of 17.9% (18.9% of males, 16.7% of females. 0.7% of harbour seals up to six weeks of age were seropositive, as were 89% of seals between six weeks and six months, 53.6% between six and 18 months and 24.2% of seals over 18 months of age. In the 18 months and over age group, seropositive animals showed statistically significant reductions in body weight (P = 0.003 and length (P < 0.001. Sera from lungworm infected harbour seals in rehabilitation (n = 6 revealed that duration of antibody persistence may be similar to that of lungworm infected cattle, but further studies are needed to confirm this. Phylogenetic analyses of MSP sequences of different marine and terrestrial mammal parasitic nematodes revealed that lungworm MSP of the genus Dictyocaulus (superfamily Trichostrongyloidea is more closely related to metastrongylid marine mammal lungworms than to trichostrongylid nematodes of terrestrial hosts.

  5. Region of interest methylation analysis: a comparison of MSP with MS-HRM and direct BSP. (United States)

    Akika, Reem; Awada, Zainab; Mogharbil, Nahed; Zgheib, Nathalie K


    The aim of this study was to compare and contrast three DNA methylation methods of a specific region of interest (ROI): methylation-specific PCR (MSP), methylation-sensitive high resolution melting (MS-HRM) and direct bisulfite sequencing (BSP). The methylation of a CpG area in the promoter region of Estrogen receptor alpha (ESR1) was evaluated by these three methods with samples and standards of different methylation percentages. MSP data were neither reproducible nor sensitive, and the assay was not specific due to non-specific binding of primers. MS-HRM was highly reproducible and a step forward into categorizing the methylation status of the samples as percent ranges. Direct BSP was the most informative method regarding methylation percentage of each CpG site. Though not perfect, it was reproducible and sensitive. We recommend the use of either method depending on the research question and target amplicon, and provided that the designed primers and expected amplicons are within recommendations. If the research question targets a limited number of CpG sites and simple yes/no results are enough, MSP may be attempted. For short amplicons that are crowded with CpG sites and of single melting domain, MS-HRM may be the method of choice though it only indicates the overall methylation percentage of the entire amplicon. Although the assay is highly reproducible, being semi-quantitative makes it of lesser interest to study ROI methylation of samples with little methylation differences. Direct BSP is a step forward as it gives information about the methylation percentage at each CpG site.

  6. An oven control system based on MCU MSP430F149

    International Nuclear Information System (INIS)

    Jing Lan; Zhu Haijun; Liu Caihong; Liu Yali; Gao Shiwei; Chinese Academia of Sciences, Beijing


    This paper introduces the structure, principle and feature of new generation of 16 bit and Flash-type microcontroller which belongs to the Texas Instruments MSP430F149 series with low power consumption and high performance. Details of the hardware structure and analysis software of the oven control system based on the microcontroller are expatiated. this systerm has the characteristics of strong function, simple struction, high reliability, strong noise resistances, no peripheral chip etc. The requirements of the temperature measurement and control system are fulfilled. (authors)

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    In recent decades, family patterns have changed significantly. National laws have taken these changes into account, recognizing new forms of unions, different to heterosexual marriage. Indeed, recently some countries have given the possibility to same-sex couples to enter into various forms of unions. Staff regulations of international organizations are not directly affected by national laws, but in the context of diversity policies, the lack of recognition of these new forms of unions, may appear to discriminate based on sexual orientation and to limit the freedom of choosing marital status. A study by the International Service for Remunerations and Pensions (iSRP) of the OECD in January 2015 (PROS Report (1015) 04) shows that in comparison with other international organizations, CERN offers the least favorable social conditions for its Staff with in a registered partnership. As part of the Five-year review in 2015, it is important that CERN aligns itself with the practice of these other organizations...

  8. Impact of pre-existing MSP142-allele specific immunity on potency of an erythrocytic Plasmodium falciparum vaccine

    Directory of Open Access Journals (Sweden)

    Bergmann-Leitner Elke S


    Full Text Available Abstract Background MSP1 is the major surface protein on merozoites and a prime candidate for a blood stage malaria vaccine. Preclinical and seroepidemiological studies have implicated antibodies to MSP1 in protection against blood stage parasitaemia and/or reduced parasite densities, respectively. Malaria endemic areas have multiple strains of Plasmodium falciparum circulating at any given time, giving rise to complex immune responses, an issue which is generally not addressed in clinical trials conducted in non-endemic areas. A lack of understanding of the effect of pre-existing immunity to heterologous parasite strains may significantly contribute to vaccine failure in the field. The purpose of this study was to model the effect of pre-existing immunity to MSP142 on the immunogenicity of blood-stage malaria vaccines based on alternative MSP1 alleles. Methods Inbred and outbred mice were immunized with various recombinant P. falciparum MSP142 proteins that represent the two major alleles of MSP142, MAD20 (3D7 and Wellcome (K1, FVO. Humoral immune responses were analysed by ELISA and LuminexTM, and functional activity of induced MSP142-specific antibodies was assessed by growth inhibition assays. T-cell responses were characterized using ex vivo ELISpot assays. Results Analysis of the immune responses induced by various immunization regimens demonstrated a strong allele-specific response at the T cell level in both inbred and outbred mice. The success of heterologous regimens depended on the degree of homology of the N-terminal p33 portion of the MSP142, likely due to the fact that most T cell epitopes reside in this part of the molecule. Analysis of humoral immune responses revealed a marked cross-reactivity between the alleles. Functional analyses showed that some of the heterologous regimens induced antibodies with improved growth inhibitory activities. Conclusion The development of a more broadly efficacious MSP1 based vaccine may be

  9. Collaboration of nuclear knowledge. Execution of science partnership project promoted by MEXT and repercussion effect obtained from the viewpoint of intellectual collaboration

    International Nuclear Information System (INIS)

    Yanagisawa, Kazuaki; Nagasawa, Naotsugu; Sasagawa, Sumiko; Nakano, Koji


    The Fujioka Technical High School (FTHS) applied to the Science Partnership Project (SPP-2006), which was financially supported by the MEXT and promoted by the Japan Science and Technology Agency, and was approved the proposal entitled as 'Nuclear Technology and Its Future for Nuclear-Cite Neighboring Students'. FTHS decided to make intellectual linkage with Takasaki Branch, Japan Atomic Energy Agency (JAEA) and with Institute for Environmental Sciences, having with the following 5 menus. 1. Outline of nuclear energy. 2. Outline of radiation application and experimental practice. 3. Radiation and health for understanding the natural radiation and radioactivity. 4. Sightseeing of nuclear facilities around Tokai-mura. 5. Reporting of SPP activities. Adding to normal lectures listed above, the authors made several educational trials from the viewpoint of intellectual linkage. First is to verify the change of interest in students through lectures on nuclear, second is to reveal that which nuclear fields are interested by a majority of students, third is to make direct comparison of intellectual ability between the students and 5 specialists. Resultantly, if one teaches correctly the basic concept of nuclear energy and radiation application as learning inputs, aparting from his mind to nuclear and understanding ability of student increased 3 times than his background level. A comprehensive faculty of the students to the 5 specialists is 1/5 before making lecture but increased markedly to 1/2 after the lecture. A majority of students understand the matter of reprocessing, reactor accidents and food irradiation but understand poorly the location and name of the commercial nuclear power plant as well as the basic function of the power reactors. The latter is however recovered by the sightseeing of commercial power plants and fuel fabrication facilities located around Tokai-mura. Namely, to seeing is to believing. To teach a radiation application and a basic idea of nuclear

  10. Expression and Evaluation of Recombinant Plasmodium knowlesi Merozoite Surface Protein-3 (MSP-3 for Detection of Human Malaria.

    Directory of Open Access Journals (Sweden)

    Jeremy Ryan De Silva

    Full Text Available Malaria remains a major health threat in many parts of the globe and causes high mortality and morbidity with 214 million cases of malaria occurring globally in 2015. Recent studies have outlined potential diagnostic markers and vaccine candidates one of which is the merozoite surface protein (MSP-3. In this study, novel recombinant Plasmodium knowlesi MSP-3 was cloned, expressed and purified in an Escherichia coli system. Subsequently, the recombinant protein was evaluated for its sensitivity and specificity. The recombinant pkMSP-3 protein reacted with sera from patients with P. knowlesi infection in both Western blot (61% and ELISA (100%. Specificity-wise, pkMSP-3 did not react with healthy donor sera in either assay and only reacted with a few non-malarial parasitic patient sera in the ELISA assay (3 of 49. In conclusion, sensitivity and specificity of pkMSP-3 was found to be high in the ELISA and Western Blot assay and thus utilising both assays in tandem would provide the best sero-diagnostic result for P. knowlesi infection.

  11. Design of Tropical Flowers Environmental Parameters Wireless Monitoring System Based on MSP430

    Directory of Open Access Journals (Sweden)

    Huang Jian-Qing


    Full Text Available Considering the importance of real-time monitoring tropical flower environment parameters, the paper designs a wireless monitoring system based on MSP430F149 for tropical flower growing parameters. The proposed system uses sensor nodes to obtain data of temperature, humidity and light intensity, sink node to collect data from sensor nodes through wireless sensor network, and monitoring center to process data downloaded from the sink node through RS232 serial port. The node hardware platform is composed of a MSP430F149 processor, AM2306 and NHZD10AI sensors used to adopt temperature, humidity and light intensity data, and an nRF905 RF chip used to receive and send data. The node software, operated in IAR Embedded Workbench, adopts C Language to do node data collection and process, wireless transmission and serial port communication. The software of monitoring center develops in VB6.0, which can provide vivid and explicit real-time monitoring platform for flower farmers.

  12. Isolation and Characterization of Vaccine Candidate Genes Including CSP and MSP1 in Plasmodium yoelii. (United States)

    Kim, Seon-Hee; Bae, Young-An; Seoh, Ju-Young; Yang, Hyun-Jong


    Malaria is an infectious disease affecting humans, which is transmitted by the bite of Anopheles mosquitoes harboring sporozoites of parasitic protozoans belonging to the genus Plasmodium . Despite past achievements to control the protozoan disease, malaria still remains a significant health threat up to now. In this study, we cloned and characterized the full-unit Plasmodium yoelii genes encoding merozoite surface protein 1 (MSP1), circumsporozoite protein (CSP), and Duffy-binding protein (DBP), each of which can be applied for investigations to obtain potent protective vaccines in the rodent malaria model, due to their specific expression patterns during the parasite life cycle. Recombinant fragments corresponding to the middle and C-terminal regions of PyMSP1 and PyCSP, respectively, displayed strong reactivity against P. yoelii -infected mice sera. Specific native antigens invoking strong humoral immune response during the primary and secondary infections of P. yoelii were also abundantly detected in experimental ICR mice. The low or negligible parasitemia observed in the secondary infected mice was likely to result from the neutralizing action of the protective antibodies. Identification of these antigenic proteins might provide the necessary information and means to characterize additional vaccine candidate antigens, selected solely on their ability to produce the protective antibodies.

  13. MSP-Tool: a VBA-based software tool for the analysis of multispecimen paleointensity data (United States)

    Monster, Marilyn; de Groot, Lennart; Dekkers, Mark


    The multispecimen protocol (MSP) is a method to estimate the Earth's magnetic field's past strength from volcanic rocks or archeological materials. By reducing the amount of heating steps and aligning the specimens parallel to the applied field, thermochemical alteration and multi-domain effects are minimized. We present a new software tool, written for Microsoft Excel 2010 in Visual Basic for Applications (VBA), that evaluates paleointensity data acquired using this protocol. In addition to the three ratios (standard, fraction-corrected and domain-state-corrected) calculated following Dekkers and Böhnel (2006) and Fabian and Leonhardt (2010) and a number of other parameters proposed by Fabian and Leonhardt (2010), it also provides several reliability criteria. These include an alteration criterion, whether or not the linear regression intersects the y axis within the theoretically prescribed range, and two directional checks. Overprints and misalignment are detected by isolating the remaining natural remanent magnetization (NRM) and the partial thermoremanent magnetization (pTRM) gained and comparing their declinations and inclinations. The NRM remaining and pTRM gained are then used to calculate alignment-corrected multispecimen plots. Data are analyzed using bootstrap statistics. The program was tested on lava samples that were given a full TRM and that acquired their pTRMs at angles of 0, 15, 30 and 90° with respect to their NRMs. MSP-Tool adequately detected and largely corrected these artificial alignment errors.

  14. Diversidad genética de la región variable de los genes msp1a y msp4 en cepas de Anaplasma marginale de México

    Directory of Open Access Journals (Sweden)

    Rafael Jiménez Ocampo


    Full Text Available La anaplasmosis es de difícil control debido a la diversidad genética de la rickettsia. La proteína Msp1a, compuesta de repetidos variables de entre 23 y 31 aminoácidos en su región variable y la proteína Msp4, son dos de las proteínas de superficie más estudiadas en A. marginale y han sido ampliamente usadas como marcadores genéticos en la caracterización de cepas de A. marginale de diferentes orígenes geográficos. En este trabajo se analizaron, la región variable de la proteína Msp1a y la proteína Msp4 de 10 cepas mexicanas. En el caso de Msp1a, se observó un patrón de segregación que contiene los repetidos (alpha, beta, beta, gama en diferentes modalidades a lo largo de aislamientos del Golfo de México, principalmente en zonas de estabilidad enzoótica, mientras que la máxima variabilidad se presentó en Tamaulipas, en aislamientos de un brote de la enfermedad, es decir en zonas de inestabilidad. La diversidad observada no es tan extensa como se esperaba y, misma que se puede explicar por la presión que el sistema inmune del hospedero ejerce contra la rickettsia y los mecanismos de esta última para evadirla. En el caso de la proteína Msp4, la secuencia fue altamente conservada tanto en nucleótidos como en aminoácidos para los aislados en estudio, aunque, se observan diferencias con lo previamente reportado en México para este marcador.

  15. Canada's Global Partnership Program

    International Nuclear Information System (INIS)

    Ellis, M.


    Curbing the proliferation of biological weapons (BW) is an essential element of the Global Partnership Against the Spread of Weapons and Materials of Mass Destruction. At the Kananaskis Summit in June 2002, G8 Leaders committed to prevent terrorists, or those that harbour them, from acquiring or developing biological weapons and related materials, equipment and technology. To this end, Canada's Global Partnership Program is investing heavily in biological non-proliferation activities in countries of the former Soviet Union. A comprehensive strategy has been developed to help improve biological safety (biosafety) and biological security (biosecurity) with provision for addressing dual-use concerns. Raising awareness and creating a self-sustaining culture of biosecurity is a key driver of the program. Through this strategy, Canada is assisting various FSU countries to: develop and implement effective and practical biosafety/biosecurity standards and guidelines; establish national and/or regional biosafety associations; develop and deliver effective biosafety and biosecurity training; put in place enhanced physical security measures and equipment. In addition to biosafety and biosecurity, the GPP supports a broad range of Biological Non-Proliferation projects and initiatives, including dozens of projects aimed at redirecting former biological weapons scientists. To date, most of these activities have been supported through Canada's contribution to the International Science and Technology Center (ISTC) and the Science and Technology Centre Ukraine (STCU).(author)

  16. Ingredients for successful partnerships

    NARCIS (Netherlands)

    S.M. Pfisterer (Stella)


    textabstractFor the development of new cross-sector partnerships it is required to know what the essence of successful partnership projects is. Which factors influence success or failure of partnerships is highly related to the specific context where partnerships operate. The literature on critical

  17. Annual Partnership Report, 2016 (United States)

    Wyoming Community College Commission, 2016


    The "Annual Partnership Report" catalogs partnerships that Wyoming community colleges established and maintained for each fiscal year. This partnership report fulfills statutory reporting requirement W.S. 21-18-202(e)(iv) which mandates the development of annual reports to the legislature on the outcomes of partnerships between colleges…

  18. Heterogeneous genetic diversity pattern in Plasmodium vivax genes encoding merozoite surface proteins (MSP) -7E, -7F and -7L. (United States)

    Garzón-Ospina, Diego; Forero-Rodríguez, Johanna; Patarroyo, Manuel A


    The msp-7 gene has become differentially expanded in the Plasmodium genus; Plasmodium vivax has the highest copy number of this gene, several of which encode antigenic proteins in merozoites. DNA sequences from thirty-six Colombian clinical isolates from P. vivax (pv) msp-7E, -7F and -7L genes were analysed for characterizing and studying the genetic diversity of these pvmsp-7 members which are expressed during the intra-erythrocyte stage; natural selection signals producing the variation pattern so observed were evaluated. The pvmsp-7E gene was highly polymorphic compared to pvmsp-7F and pvmsp-7L which were seen to have limited genetic diversity; pvmsp-7E polymorphism was seen to have been maintained by different types of positive selection. Even though these copies seemed to be species-specific duplications, a search in the Plasmodium cynomolgi genome (P. vivax sister taxon) showed that both species shared the whole msp-7 repertoire. This led to exploring the long-term effect of natural selection by comparing the orthologous sequences which led to finding signatures for lineage-specific positive selection. The results confirmed that the P. vivax msp-7 family has a heterogeneous genetic diversity pattern; some members are highly conserved whilst others are highly diverse. The results suggested that the 3'-end of these genes encode MSP-7 proteins' functional region whilst the central region of pvmsp-7E has evolved rapidly. The lineage-specific positive selection signals found suggested that mutations occurring in msp-7s genes during host switch may have succeeded in adapting the ancestral P. vivax parasite population to humans.

  19. MSP-HTPrimer: a high-throughput primer design tool to improve assay design for DNA methylation analysis in epigenetics. (United States)

    Pandey, Ram Vinay; Pulverer, Walter; Kallmeyer, Rainer; Beikircher, Gabriel; Pabinger, Stephan; Kriegner, Albert; Weinhäusel, Andreas


    Bisulfite (BS) conversion-based and methylation-sensitive restriction enzyme (MSRE)-based PCR methods have been the most commonly used techniques for locus-specific DNA methylation analysis. However, both methods have advantages and limitations. Thus, an integrated approach would be extremely useful to quantify the DNA methylation status successfully with great sensitivity and specificity. Designing specific and optimized primers for target regions is the most critical and challenging step in obtaining the adequate DNA methylation results using PCR-based methods. Currently, no integrated, optimized, and high-throughput methylation-specific primer design software methods are available for both BS- and MSRE-based methods. Therefore an integrated, powerful, and easy-to-use methylation-specific primer design pipeline with great accuracy and success rate will be very useful. We have developed a new web-based pipeline, called MSP-HTPrimer, to design primers pairs for MSP, BSP, pyrosequencing, COBRA, and MSRE assays on both genomic strands. First, our pipeline converts all target sequences into bisulfite-treated templates for both forward and reverse strand and designs all possible primer pairs, followed by filtering for single nucleotide polymorphisms (SNPs) and known repeat regions. Next, each primer pairs are annotated with the upstream and downstream RefSeq genes, CpG island, and cut sites (for COBRA and MSRE). Finally, MSP-HTPrimer selects specific primers from both strands based on custom and user-defined hierarchical selection criteria. MSP-HTPrimer produces a primer pair summary output table in TXT and HTML format for display and UCSC custom tracks for resulting primer pairs in GTF format. MSP-HTPrimer is an integrated, web-based, and high-throughput pipeline and has no limitation on the number and size of target sequences and designs MSP, BSP, pyrosequencing, COBRA, and MSRE assays. It is the only pipeline, which automatically designs primers on both genomic

  20. Satisfactory safety and immunogenicity of MSP3 malaria vaccine candidate in Tanzanian children aged 12–24 months

    Directory of Open Access Journals (Sweden)

    Segeja Method D


    Full Text Available Abstract Background Development and deployment of an effective malaria vaccine would complement existing malaria control measures. A blood stage malaria vaccine candidate, Merozoite Surface Protein-3 (MSP3, produced as a long synthetic peptide, has been shown to be safe in non-immune and semi-immune adults. A phase Ib dose-escalating study was conducted to assess the vaccine's safety and immunogenicity in children aged 12 to 24 months in Korogwe, Tanzania ( number: NCT00469651. Methods This was a double-blind, randomized, controlled, dose escalation phase Ib trial, in which children were given one of two different doses of the MSP3 antigen (15 μg or 30 μg or a control vaccine (Engerix B. Children were randomly allocated either to the MSP3 candidate malaria vaccine or the control vaccine administered at a schedule of 0, 1, and 2 months. Immunization with lower and higher doses was staggered for safety reasons starting with the lower dose. The primary endpoint was safety and reactogenicity within 28 days post-vaccination. Blood samples were obtained at different time points to measure immunological responses. Results are presented up to 84 days post-vaccination. Results A total of 45 children were enrolled, 15 in each of the two MSP3 dose groups and 15 in the Engerix B group. There were no important differences in reactogenicity between the two MSP3 groups and Engerix B. Grade 3 adverse events were infrequent; only five were detected throughout the study, all of which were transient and resolved without sequelae. No serious adverse event reported was considered to be related to MSP3 vaccine. Both MSP3 dose regimens elicited strong cytophilic IgG responses (subclasses IgG1 and IgG3, the isotypes involved in the monocyte-dependant mechanism of Plasmodium falciparum parasite-killing. The titers reached are similar to those from African adults having reached a state of premunition. Furthermore, vaccination induced seroconversion in

  1. Formation of the food vacuole in Plasmodium falciparum: a potential role for the 19 kDa fragment of merozoite surface protein 1 (MSP1(19.

    Directory of Open Access Journals (Sweden)

    Anton R Dluzewski


    Full Text Available Plasmodium falciparum Merozoite Surface Protein 1 (MSP1 is synthesized during schizogony as a 195-kDa precursor that is processed into four fragments on the parasite surface. Following a second proteolytic cleavage during merozoite invasion of the red blood cell, most of the protein is shed from the surface except for the C-terminal 19-kDa fragment (MSP1(19, which is still attached to the merozoite via its GPI-anchor. We have examined the fate of MSP1(19 during the parasite's subsequent intracellular development using immunochemical analysis of metabolically labeled MSP1(19, fluorescence imaging, and immuno-electronmicroscopy. Our data show that MSP1(19 remains intact and persists to the end of the intracellular cycle. This protein is the first marker for the biogenesis of the food vacuole; it is rapidly endocytosed into small vacuoles in the ring stage, which coalesce to form the single food vacuole containing hemozoin, and persists into the discarded residual body. The food vacuole is marked by the presence of both MSP1(19 and the chloroquine resistance transporter (CRT as components of the vacuolar membrane. Newly synthesized MSP1 is excluded from the vacuole. This behavior indicates that MSP1(19 does not simply follow a classical lysosome-like clearance pathway, instead, it may play a significant role in the biogenesis and function of the food vacuole throughout the intra-erythrocytic phase.

  2. Identificación de un epítope conformacional en el extremo carboxilo de la proteína MSP-1 de P. Falciparum

    Directory of Open Access Journals (Sweden)

    Julio C. Calvo


    Full Text Available El fragmento carboxilo terminal, rico en cisteínas, de la proteína 1 de superficie del merozoito (MSP-1 desempeña un papel importante en la invasión del merozoito de la malaria al eritrocito. Anticuerpos contra esta región de MSP-l inhiben la invasión.

  3. Western Hemisphere Knowledge Partnerships (United States)

    Malone, T. F.


    , and application of knowledge concerning the nature of -- and interaction among -- matter, living organisms, energy, information, and human behavior. This strategy calls for innovative partnerships among the physical, biological, health, and social sciences, engineering, and the humanities. New kinds of partnership must also be forged among academia, business and industry, governments, and nongovernmental organizations. Geophysicists can play an important role in these partnerships. A focus for these partnerships is to manage the individual economic productivity that drives both human development and global change. As world population approaches stability during the twenty-first century, individual economic productivity will be the critical link between the human and the natural systems on planet Earth. AGU is among a core group of individuals and institutions proposing Western Hemisphere Knowledge Partnerships (WHKP) to test the hypothesis that knowledge, broadly construed, is an important organizing principle in choosing a path into the future. The WHKP agenda includes: (1) life-long learning, (2) the health and resilience of natural ecosystems, (3) eco-efficiency in economic production and consumption, (4) extension of national income accounts, (5) environmentally benign sources of energy, (6) delivery of health care, (7) intellectual property rights, and (8) networks for action by local communities.Collaboratories and distance education technologies will be major tools. A panel of experts will explore this proposal.

  4. Common MspI RFLP of the human fibronectin gene (FN1)

    Energy Technology Data Exchange (ETDEWEB)

    Gardella, R; Colombi, M; Barlati, S


    The probe used, pFH154, contains a sequence of 2.5 kb of the fibronectin cDNA inserted in pAT153/Pvu/8 plasmid vector. The recombinant plasmid and the HindIII/BamHI purified cDNA insert give identical patterns. MspI (C/CGG) (Promega Biotec) detects invariant bands at 8.5, 4.2, 2.5, 2.1, 1.55, 1.4, 1.1 and 0.75 kb in addition to a simple two allele polymorphism with a band at either 0.35 kb (F1) or 2.7 kb (F2). Co-dominant segregation was demonstrated in 6 families.

  5. A Multi-wavelength Study of an Isolated MSP Bow Shock (United States)

    Romani, Roger W.; Slane, Patrick; Green, Andrew


    PSR J2124-3358 is the only single MSP known to sport an Halpha bow shock. This shock, now also seen in the UV, encloses an unusual X-ray pulsar wind nebula (PWN) with a long off-axis trail. Combining the X-ray and UV images with AAT/KOALA integral field spectroscopy of the Halpha emission, we have an unusually complete picture of the pulsar's (101 km/s transverse) motion and the latitudinal distribution of its wind flux. These images reveal the 3-D orientation of a hard-spectrum PWN jet and a softer equatorial outflow. Within the context of a thin shock model, we can constrain the total energy output of the pulsar and the neutron star moment of inertia. The IFU spectra show extreme Balmer dominance, which also constrains the nature of the UV shock emission.


    Energy Technology Data Exchange (ETDEWEB)

    Brian McPherson; Rick Allis; Barry Biediger; Joel Brown; Jim Cappa; George Guthrie; Richard Hughes; Eugene Kim; Robert Lee; Dennis Leppin; Charles Mankin; Orman Paananen; Rajesh Pawar; Tarla Peterson; Steve Rauzi; Jerry Stuth; Genevieve Young


    The Southwest Partnership Region includes six whole states, including Arizona, Colorado, Kansas, New Mexico, Oklahoma, and Utah, roughly one-third of Texas, and significant portions of adjacent states. The Partnership comprises a large, diverse group of expert organizations and individuals specializing in carbon sequestration science and engineering, as well as public policy and outreach. The main objective of the Southwest Partnership project is to achieve an 18% reduction in carbon intensity by 2012. The Partnership made great progress in this first year. Action plans for possible Phase II carbon sequestration pilot tests in the region are almost finished, including both technical and non-technical aspects necessary for developing and carrying out these pilot tests. All partners in the Partnership are taking an active role in evaluating and ranking optimum sites and technologies for capture and storage of CO{sub 2} in the Southwest Region. We are identifying potential gaps in all aspects of potential sequestration deployment issues.

  7. Financial services partnerships labor-management dynamics

    CERN Document Server

    Samuel, Peter


    The purpose of this book is to evaluate the debate on partnership, using original research data. Samuel provides a novel categorisation with which to synthesise and clarify a highly diverse literature on labour-management partnership, thus helping to refine the contemporary partnership debate. Secondly, he clarifies the circumstances under which 'effective' labour-management partnership is possible, while simultaneously elaborating why the achievement of 'mutual gains' is highly improbable in a liberal-market context. Thirdly, the book presents an integrated analysis of the interplay between macro-, meso- (industry) and micro-level factors. Fourthly, the research design enables the study to go beyond the case studies to make defendable empirical generalizations at the level of the industry. Finally, it advances a theoretical explanation of labour-management partnerships in 'liberal market' economies by bridging two opposing neo-institutional positions in the social sciences.

  8. Multi-stakeholder partnerships for transfer of environmentally soundtechnologies

    International Nuclear Information System (INIS)

    Morsink, Karlijn; Hofman, Peter S.; Lovett, Jon C.


    Multi-Stakeholder Partnerships can overcome many of the problems which exist with the transfer of Environmentally Sound Technologies (ESTs) from developed to developing countries, but as yet they have not been explored in detail in the negotiations under the United Nations Framework Convention on Climate Change (UNFCCC). Technology transfer is an important part of the UNFCCC, but the mechanism for achieving this is problematic. Developed countries prefer a market approach whereas developing countries tend to negotiate for direct grants. Multi-stakeholder partnerships offer a pathway through which technology is transferred and developing country capacity enhanced, while the interests of developed country private enterprise innovators are also protected. We present opinions and a case-study on multi-stakeholder partnerships and discuss some of the advantages that multi-stakeholder partners canoffer. - Research Highlights: → Multi-stakeholder partnerships offer potential for transfer of environmentally sound technologies to developing countries. → MSPs can protect developed country industry intellectual property rights. → The Philips EST light bulb plant in Lesotho is an example of a successful energy MSP.

  9. Teaching how to read and write science: a library-journal partnership / Lehren, wie man Wissenschaft liest und schreibt: eine Partnerschaft von Bibliothek und Zeitschrift

    Directory of Open Access Journals (Sweden)

    Petrak, Jelka


    Full Text Available SettingThe Croatian Medical Journal (CMJ is a general medical journal published in English. It is the only Croatian medical journal covered by the most selective bibliographic databases, eg. SCI-Expanded and Current Contents. The Central Medical Library (CML is the most important Croatian medical library serving as central point for biomedical information. Both are affiliated to Croatia's largest and oldest medical school, the University of Zagreb's School of Medicine. The CMJ started publishing in English in 1992. Its editorial board asked CML to assist in formulating change policy and bringing best editorial practice to the local setting. When CMJ introduced an "author-helpful" policy, CML supported authors to find literature and formatting references. CMJ also co-opted the head-librarian to the editorial board. Teaching how to read and write science: a library-journal partnershipEarly in their work, the CMJ editorial board learned that Croatian physicians had important and interesting data but inadequate skills to present them in a scientific article. To alleviate the lack of knowledge in research methods and writing, a mandatory course in scientific methodology and communication was developed and introduced into the university curriculum. The course runs since the academic year 1995/96 focusing on (1 principles of scientific research; (2 finding medical information; (3 study design and presentation of data; (4 writing a scientific article. The course comprises three components: lectures, discussions in medium-sized groups and exercises in problem solving in small groups. Three librarians participate in the course, giving a core lecture and hands-on exercises in problem-solving using PubMed. In 2002 and 2004 CMJ and CML started two continuing courses. Planning and Writing about Research in Medicine and Finding and Appraisal Medical Information respectively. The courses are aimed at young academic physicians and general medicine practitioners

  10. Partnership for Prescription Assistance (United States)

    ... may use our name without our permission. The Partnership for Prescription Assistance will help you find the ... Events Blog Facebook Twitter Start living better. The Partnership for Prescription Assistance helps qualifying patients without prescription ...

  11. Partnerships panel: natural, resource partnerships: literature synthesis and research agenda (United States)

    Steve Selin; Nancy Myers


    This paper presents a summary of an annotated bibliography on natural resource partnerships. Resource areas and management functions addressed in the partnership literature are examined. Partnership research is summarized and broken into categories including: Partnership outcomes, assessing the potential for partnerships, characteristics of successful partnerships,...

  12. Impact challenges in community science-with-practice: lessons from PROSPER on transformative practitioner-scientist partnerships and prevention infrastructure development. (United States)

    Spoth, Richard; Greenberg, Mark


    At present, evidence-based programs (EBPs) to reduce youth violence are failing to translate into widespread community practice, despite their potential for impact on this pervasive public health problem. In this paper we address two types of challenges in the achievement of such impact, drawing upon lessons from the implementation of a partnership model called PROSPER. First, we address five key challenges in the achievement of community-level impact through effective community planning and action: readiness and mobilization of community teams; maintaining EBP implementation quality; sustaining community teams and EBPs; demonstrating community-level impact; and continuous, proactive technical assistance. Second, we consider grand challenges in the large-scale translation of EBPs: (1) building, linking and expanding existing infrastructures to support effective EBP delivery systems, and (2) organizing networks of practitioner-scientist partnerships-networks designed to integrate diffusion of EBPs with research that examines effective strategies to do so. The PROSPER partnership model is an evidence-based delivery system for community-based prevention and has evolved through two decades of NIH-funded research, assisted by land grant universities' Cooperative Extension Systems. Findings and lessons of relevance to each of the challenges are summarized. In this context, we outline how practitioner-scientist partnerships can serve to transform EBP delivery systems, particularly in conjunction with supportive federal policy.

  13. Partnerships as Interpellation

    DEFF Research Database (Denmark)

    Andersen, Sigrid Bjerre; Jensen, Steffen


    of the political partnership between Liberia and the European Union, and the partnership between a South African and a Danish NGO. Both illustrate how neither donor nor recipient, as it is otherwise often assumed, can univocally announce a partnership. Rather, representatives of the institutions involved mutually...

  14. Partnerships – Limited partnerships and limited liability limited partnerships


    Henning, Johan J.


    Consideration of the Limited Liability Partnership Act 2000 which introduced a new corporate entity, carrying the designations “partnership” and “limited” which allow members to limit their liability whilst organising themselves internally as a partnership. Article by Professor Johan Henning (Director of the Centre for Corporate Law and Practice, IALS and Dean of the Faculty of Law, University of the Free State, South Africa). Published in Amicus Curiae - Journal of the Institute of Advanced ...

  15. Building Sustainable Capacity with University Partnerships (United States)

    Harris, J. M.


    Universities can play an important role in building scientific and technical capacity by providing educational opportunities for local and regional populations in developing countries. These opportunities may be short term or long term through for example faculty exchanges, student exchanges, and collaborative teaching and research activities. As the demand for talented graduates expands in developing countries, local universities face competition for students, lecturers, and professors from the same industries and communities they serve. This competition is in many ways counterproductive to building the sustainable human resource that is needed to support local development, management, and governance. Such competition is particularly evident for top science and engineering students in energy rich countries. University partnerships, e.g., in particular those between universities in OECD countries and universities in developing countries, have an important role to play in bridging the gap between today's lack of capacity and a sustainable human resource for the future. Such university partnerships, however, face many challenges, some of which can be traced to organizational and cultural differences In this presentation, I will discuss how university partnerships are formed, some of the benefits to partners, and some pitfalls to avoid during implementation of university partnerships. The examples are taken from Stanford partnerships that involve geoscience and engineering, and will include representative goals and content of the example partnerships. These partnerships I'll describe are actually trilateral, with partners from two or more universities and a private company or government agency. I conclude the presentation with a brief discussion on multiculturalism, perhaps the most important consideration when planning a partnership between diverse organizations. Organizers of partnerships must recognize the fact that multiculturalism and diversity are assets that

  16. Quantifying the importance of MSP1-19 as a target of growth-inhibitory and protective antibodies against Plasmodium falciparum in humans.

    Directory of Open Access Journals (Sweden)

    Danny W Wilson

    Full Text Available BACKGROUND: Antibodies targeting blood stage antigens are important in protection against malaria, but the key targets and mechanisms of immunity are not well understood. Merozoite surface protein 1 (MSP1 is an abundant and essential protein. The C-terminal 19 kDa region (MSP1-19 is regarded as a promising vaccine candidate and may also be an important target of immunity. METHODOLOGY/FINDINGS: Growth inhibitory antibodies against asexual-stage parasites and IgG to recombinant MSP1-19 were measured in plasma samples from a longitudinal cohort of 206 children in Papua New Guinea. Differential inhibition by samples of mutant P. falciparum lines that expressed either the P. falciparum or P. chabaudi form of MSP1-19 were used to quantify MSP1-19 specific growth-inhibitory antibodies. The great majority of children had detectable IgG to MSP1-19, and high levels of IgG were significantly associated with a reduced risk of symptomatic P. falciparum malaria during the 6-month follow-up period. However, there was little evidence of PfMSP1-19 specific growth inhibition by plasma samples from children. Similar results were found when testing non-dialysed or dialysed plasma, or purified antibodies, or when measuring growth inhibition in flow cytometry or microscopy-based assays. Rabbit antisera generated by immunization with recombinant MSP1-19 demonstrated strong MSP1-19 specific growth-inhibitory activity, which appeared to be due to much higher antibody levels than human samples; antibody avidity was similar between rabbit antisera and human plasma. CONCLUSIONS/SIGNIFICANCE: These data suggest that MSP1-19 is not a major target of growth inhibitory antibodies and that the protective effects of antibodies to MSP1-19 are not due to growth inhibitory activity, but may instead be mediated by other mechanisms. Alternatively, antibodies to MSP1-19 may act as a marker of protective immunity.

  17. School and University Partnerships: The Role of Teacher Education Institutions and Primary Schools in the Development of Preservice Teachers' Science Teaching Efficacy (United States)

    Petersen, Jacinta E.; Treagust, David F.


    Science in the Australian primary school context is in a state of renewal with the recent implementation of the Australian Curriculum: Science. Despite this curriculum renewal, the results of primary students in science have remained static. Science in Australia has been identified as one of the least taught subjects in the primary school…

  18. The high accuracy data processing system of laser interferometry signals based on MSP430 (United States)

    Qi, Yong-yue; Lin, Yu-chi; Zhao, Mei-rong


    Generally speaking there are two orthogonal signals used in single-frequency laser interferometer for differentiating direction and electronic subdivision. However there usually exist three errors with the interferential signals: zero offsets error, unequal amplitude error and quadrature phase shift error. These three errors have a serious impact on subdivision precision. Based on Heydemann error compensation algorithm, it is proposed to achieve compensation of the three errors. Due to complicated operation of the Heydemann mode, a improved arithmetic is advanced to decrease the calculating time effectively in accordance with the special characteristic that only one item of data will be changed in each fitting algorithm operation. Then a real-time and dynamic compensatory circuit is designed. Taking microchip MSP430 as the core of hardware system, two input signals with the three errors are turned into digital quantity by the AD7862. After data processing in line with improved arithmetic, two ideal signals without errors are output by the AD7225. At the same time two original signals are turned into relevant square wave and imported to the differentiating direction circuit. The impulse exported from the distinguishing direction circuit is counted by the timer of the microchip. According to the number of the pulse and the soft subdivision the final result is showed by LED. The arithmetic and the circuit are adopted to test the capability of a laser interferometer with 8 times optical path difference and the measuring accuracy of 12-14nm is achieved.

  19. Study of mixed programming gamma spectrum acquisition method based on MSP430F4618

    International Nuclear Information System (INIS)

    Li Yuezhong; Tang Bin; Zhang Zhongliang; Xie Xiaolin


    In order to reduce the hand-held gamma spectrometer measurements dead time and to complete the low-voltage and low-power design, the spectrum signal acquisition circuit is constituted by the ultra-low power microcontroller MSP430F4618 and its external signal conditioning circuit, anti-coincidence circuit interface and its on-chip sample hold and A/D converter. C language programming and assembly one have been used together. The sample hold and A/D conversion and spectrum acquisition programming is accomplished by assembly language, and the system monitoring and task scheduler designing is accomplished by C language programming. The handhold gamma spectrometer power supply, which just uses two No.5 rechargeable batteries, is designed by high-efficiency DC-DC circuit. The prototype gamma spectrometer is developed by the method, and its testing shows that the implementation of spectrum acquisition time is shorten by twice to 3 times, that is, the dead measurement can be reduced; and the machine operating current does not exceed 150 mA. By using two 2400 mAh No.5 rechargeable battery, the machine can work continuously more than 10 hours, and it can meet the application requirements. (authors)

  20. The risk of developing cervical cancer in Mexican women is associated to CYP1A1 MspI polymorphism. (United States)

    Juárez-Cedillo, Teresa; Vallejo, Maite; Fragoso, José Manuel; Hernández-Hernández, Dulce Maria; Rodríguez-Pérez, José Manuel; Sánchez-García, Sergio; del Carmen García-Peña, María; García-Carrancá, Alejandro; Mohar-Betancourt, Alejandro; Granados, Julio; Vargas-Alarcón, Gilberto


    The aim of the study was to evaluate the association of two CYP1A1 polymorphisms (Msp1 and exon 7) with cervical cancer in Mexican women considering their smoking habit. The polymorphisms were determined in 310 individuals (155 with cervical cancer and 155 healthy controls). Women with MspI T/C or C/C showed increased risk of developing cervical cancer (3.7- and 8.3-fold increase, respectively) compared to women with T/T genotype. When smoking habit was considered, the risk for non-smokers with T/C and C/C genotypes was similar (5.2 and 4.1, respectively), whereas smoking women with C/C genotype showed a 19.4-fold increase of cervical cancer. Number of child births, number of sexual partners and marital status were strong risk factors for developing cervical cancer in women with T/T genotype; however, in women with T/C genotype, only the number of child births and sexual partners had a significant influence. These results suggest an important role of the CYP1A1 MspI polymorphism in the risk of developing cervical cancer.

  1. VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis elegans.

    Directory of Open Access Journals (Sweden)

    Sung Min Han

    Full Text Available Mutations in VAPB/ALS8 are associated with amyotrophic lateral sclerosis (ALS and spinal muscular atrophy (SMA, two motor neuron diseases that often include alterations in energy metabolism. We have shown that C. elegans and Drosophila neurons secrete a cleavage product of VAPB, the N-terminal major sperm protein domain (vMSP. Secreted vMSPs signal through Roundabout and Lar-like receptors expressed on striated muscle. The muscle signaling pathway localizes mitochondria to myofilaments, alters their fission/fusion balance, and promotes energy production. Here, we show that neuronal loss of the C. elegans VAPB homolog triggers metabolic alterations that appear to compensate for muscle mitochondrial dysfunction. When vMSP levels drop, cytoskeletal or mitochondrial abnormalities in muscle induce elevated DAF-16, the Forkhead Box O (FoxO homolog, transcription factor activity. DAF-16 promotes muscle triacylglycerol accumulation, increases ATP levels in adults, and extends lifespan, despite reduced muscle mitochondria electron transport chain activity. Finally, Vapb knock-out mice exhibit abnormal muscular triacylglycerol levels and FoxO target gene transcriptional responses to fasting and refeeding. Our data indicate that impaired vMSP signaling to striated muscle alters FoxO activity, which affects energy metabolism. Abnormalities in energy metabolism of ALS patients may thus constitute a compensatory mechanism counterbalancing skeletal muscle mitochondrial dysfunction.

  2. Boundary Dynamics: Implications for Building Parent-School Partnerships (United States)

    Price-Mitchell, Marilyn


    This article draws on systems theory, complexity theory, and the organizational sciences to engage boundary dynamics in the creation of parent-school partnerships. These partnerships help children succeed through an emergent process of dialogue and relationship building in the peripheral spaces where parents and schools interact on behalf of…

  3. The evolution and diversity of a low complexity vaccine candidate, merozoite surface protein 9 (MSP-9), in Plasmodium vivax and closely related species. (United States)

    Chenet, Stella M; Pacheco, M Andreína; Bacon, David J; Collins, William E; Barnwell, John W; Escalante, Ananias A


    The merozoite surface protein-9 (MSP-9) has been considered a target for an anti-malarial vaccine since it is one of many proteins involved in the erythrocyte invasion, a critical step in the parasite life cycle. Orthologs encoding this antigen have been found in all known species of Plasmodium parasitic to primates. In order to characterize and investigate the extent and maintenance of MSP-9 genetic diversity, we analyzed DNA sequences of the following malaria parasite species: Plasmodium falciparum, Plasmodium reichenowi, Plasmodium chabaudi, Plasmodium yoelii, Plasmodium berghei, Plasmodium coatneyi, Plasmodium gonderi, Plasmodium knowlesi, Plasmodium inui, Plasmodium simiovale, Plasmodium fieldi, Plasmodium cynomolgi and Plasmodium vivax and evaluated the signature of natural selection in all MSP-9 orthologs. Our findings suggest that the gene encoding MSP-9 is under purifying selection in P. vivax and closely related species. We further explored how selection affected different regions of MSP-9 by comparing the polymorphisms in P. vivax and P. falciparum, and found contrasting patterns between these two species that suggest differences in functional constraints. This observation implies that the MSP-9 orthologs in human parasites may interact differently with the host immune response. Thus, studies carried out in one species cannot be directly translated into the other. Copyright © 2013 Elsevier B.V. All rights reserved.

  4. Design of the control system for full-color LED display based on MSP430 MCU (United States)

    Li, Xue; Xu, Hui-juan; Qin, Ling-ling; Zheng, Long-jiang


    The LED display incorporate the micro electronic technique, computer technology and information processing as a whole, it becomes the most preponderant of a new generation of display media with the advantages of bright in color, high dynamic range, high brightness and long operating life, etc. The LED display has been widely used in the bank, securities trading, highway signs, airport and advertising, etc. According to the display color, the LED display screen is divided into monochrome screen, double color display and full color display. With the diversification of the LED display's color and the ceaseless rise of the display demands, the LED display's drive circuit and control technology also get the corresponding progress and development. The earliest monochrome screen just displaying Chinese characters, simple character or digital, so the requirements of the controller are relatively low. With the widely used of the double color LED display, the performance of its controller will also increase. In recent years, the full color LED display with three primary colors of red, green, blue and grayscale display effect has been highly attention with its rich and colorful display effect. Every true color pixel includes three son pixels of red, green, blue, using the space colour mixture to realize the multicolor. The dynamic scanning control system of LED full-color display is designed based on MSP430 microcontroller technology of the low power consumption. The gray control technology of this system used the new method of pulse width modulation (PWM) and 19 games show principle are combining. This method in meet 256 level grayscale display conditions, improves the efficiency of the LED light device, and enhances the administrative levels feels of the image. Drive circuit used 1/8 scanning constant current drive mode, and make full use of the single chip microcomputer I/O mouth resources to complete the control. The system supports text, pictures display of 256 grayscale

  5. Partnership for Environmental Technology Education

    International Nuclear Information System (INIS)

    Dickinson, Paul R.; Fosse, Richard


    The need for broad cooperative effort directed toward the enhancement of science and mathematics education, including environmental science and technology has been recognized as a national priority by government, industry, and the academic community alike. In an effort to address this need, the Partnership for Environmental Technology Education (PETE) has been established in the five western states of Arizona, California, Hawaii, Nevada and Utah. PETE'S overall objectives are to link the technical resources of the DOE, ERA, and NASA Laboratories and private industry with participating community colleges to assist in the development and presentation of curricula for training environmental-Hazardous Materials Technicians and to encourage more transfer students to pursue studies in environmental science at four-year institutions. The program is co-sponsored by DOE and EPA. DoD participation is proposed. PETE is being evaluated by its sponsors as a regional pilot with potential for extension nationally. (author)

  6. In the Footsteps of Roger Revelle: A STEM Partnership Between Scripps Institution of Oceanography, Office of Naval Research and Middle School Science Students Bringing Next Generation Science Standards into the Classroom through Ocean Science (United States)

    Brice, D.; Appelgate, B., Jr.; Mauricio, P.


    Now in its tenth year, "In the Footsteps of Roger Revelle" (IFRR) is a middle school science education program that draws student interest, scientific content and coherence with Next Generation Science Standards from real-time research at sea in fields of physical science. As a successful collaboration involving Scripps Institution of Oceanography (SIO),Office of Naval Research (ONR), and San Marcos Middle School (SMMS), IFRR brings physical oceanography and related sciences to students at the San Marcos Middle School in real-time from research vessels at sea using SIO's HiSeasNet satellite communication system. With a generous grant from ONR, students are able to tour the SIO Ships and spend a day at sea doing real oceanographic data collection and labs. Through real-time and near-realtime broadcasts and webcasts, students are able to share data with scientists and gain an appreciation for the value of Biogeochemical research in the field as it relates to their classroom studies. Interaction with scientists and researchers as well as crew members gives students insights into not only possible career paths, but the vital importance of cutting edge oceanographic research on our society. With their science teacher on the ship as an education outreach specialist or ashore guiding students in their interactions with selected scientists at sea, students observe shipboard research being carried out live via videoconference, Skype, daily e-mails, interviews, digital whiteboard sessions, and web interaction. Students then research, design, develop, deploy, and field-test their own data-collecting physical oceanography instruments in their classroom. The online interactive curriculum models the Next Generation Science Standards encouraging active inquiry and critical thinking with intellectually stimulating problem- solving, enabling students to gain critical insight and skill while investigating some of the most provocative questions of our time, and seeing scientists as

  7. Cogema's transatlantic partnership

    International Nuclear Information System (INIS)

    McMurphy, M.; Ihde, R.


    Cogema's transatlantic partnership, the B+W Fuel Company, is a natural evolution of Cogema's US fuel cycle activities. The partnership in which important elements of the French nuclear industry teamed with a long-established, well-respected US industrial partner to build a company for the future is explained. 1 fig

  8. Features partnership in auditing

    Directory of Open Access Journals (Sweden)

    V.P. Bondar


    Full Text Available The notion of «institution partnerships in the audit» and its importance in Ukraine. Done overview of international experience in the Institute of partnerships in the audit business. Determined the nature of the audit, rights, duties and powers of the partnership during the audit. Done distribution of functions between the partner and the engagement partner in the synthesis of these blocks: taking on a new customer service or continued cooperation with existing customers (clients; familiarization with activities of customer audits, including an understanding of its internal control system; identification and assessment of risks of material misstatement of accounting; audit process and the audit and the formation of the final judgment. On the basis of the distribution of functions between the partner and the engagement partner, defined the overall structure of management system auditing firm. These conditions for implementation of partnerships in the audit business, and identified a number of advantages and disadvantages of partnerships for auditing.

  9. The role of the International Society for Applied Ethology (ISAE) in the global development of animal welfare science and its relationship with the OIE; strength through partnership (United States)

    The objective of this presentation is to introduce the ISAE and to highlight members’ roles in the development and implementation of OIE’s animal welfare standards. Animal welfare science is a young discipline. Originally, welfare science was heavily focused on animal behavior (ethology), but it is ...

  10. The SCOAP3 initiative and the Open Access Article-Processing-Charge market: global partnership and competition improve value in the dissemination of science

    CERN Document Server

    Romeu, Clément; Kohls, Alexander; Mansuy, Anne; Mele, Salvatore; Vesper, Martin


    The SCOAP3 (Sponsoring Consortium for Open Access Publishing in Particle Physics) initiative is an international partnership to convert to Open Access the published literature in the field of High-Energy Physics (HEP). It has been in operation since January 2014, and covers more than 4’000 articles/year. Originally initiated by CERN, the European Organization for Nuclear Research, and now counting partners representing 41 countries and 3 intergovernmental organizations, SCOAP3 has successfully converted to Open Access all, or part of, 6 HEP journals previously restricted to subscribers. It is also supporting publication of articles in 4 existing Open Access journals. As a “Gold” Open Access initiative, SCOAP3 pays Article Processing Charges (APCs), as publishers’ source of revenue for the publication service. Differentiating itself from other Open Access initiatives, SCOAP3 set APCs through a tendering process, correlating quality and price, at consistent conditions across participating publishers. Th...

  11. Genotype analysis of partial growth hormone gene (GH891│MspI in Pesisir cattle and Simmental-Pesisir crossbred cattle

    Directory of Open Access Journals (Sweden)

    T. Hartatik


    Full Text Available Growth hormone gene that controls metabolism and body size of animals and polymorphism of the gene is known related to performance of livestock. Identification of gene polymorphisms was important to get early information to determine genetic markers associated with economically desirable traits. Genetic mapping is one of important characterizations in the selection process. Pesisir cattle is one of local cattle in Indonesia that are reared in West Sumatera and have become adaptive to local environment. The present study aimed to identify the genotype of Growth Hormone gene (GH891│MspI of the Pesisir cattle and crossbred Simmental-Pesisir cattle (designated as SimPes and relationship between growth performance (body weight and body size. The present study was conducted to 30 blood samples consisted of 15 Pesisir cattle and 15 SimPes cattle. Body weight and body size were measured at 12-18 months of age. The Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP method was used in this research. The results showed that there exist three variant genotypes (MspI-/-, MspI+/-, MspI+/+ and that allele frequencies of MspI- and MspI+ were 53.3% and 46.7%, respectively. Non-significant effect has found between GH’s genotype and growth traits (Body measurement and body weight in both of breed cattle. In conclusion, three variant genotypes (GH891│MspI in Pesisir and SimPes (Simmental x Pesisir cattle population were found and no significant effect on growth trait performance.

  12. Immune response and biochemistry of calves immunized with rMSP1a ( Anaplasma marginale using carbon nanotubes as carrier molecules

    Directory of Open Access Journals (Sweden)

    Bruna Torres Silvestre


    Full Text Available Abstract Vaccination against Anaplasma marginale has been considered an important control strategy for bovine anaplasmosis. Recently, mice immunized with rMSP1 a linked to carbon nanotubes (MWNT showed significant immune responses, generating a new possibility for use of an inactivated vaccine. The objective of this study was to investigate the cellular and humoral responses in calves immunized with MWNT+rMSP1a , associated with inactivated vaccine of A. marginale produced in vitro, and evaluate the toxic effects of the MWNT on renal and hepatic function. rMSP1a was covalently linked to MWNT. Inactivated vaccine (AmUFMG2 was produced by cultivating A. marginale in IDE8 cells. Twenty-four Holstein calves were divided (four groups and immunized subcutaneously with PBS and non-carboxylated MWNT (control, G1, AmUFMG2 (G2, MWNT+rMSP1a (G3, and AmUFMG2 with MWNT+rMSP1a (G4. Blood samples were collected for total leukocyte counts, biochemical profiling and evaluation of the cellular and humoral response. Immunization with MWNT+rMSP1a induced increase in the total number of leukocytes, NK cells, in the lymphocyte populations and higher levels of antibodies compared to calves immunized only with AmUFMG2. Furthermore, MWNT did not induce changes in the biochemical profile. These data indicate that MWNT+rMSP1a were able to induce the immune responses more efficiently than AmUFMG2 alone, without generating toxicity.

  13. US utility partnerships

    International Nuclear Information System (INIS)

    Worthington, B.


    Activities of the United States Energy Association were reviewed, as well as the manner in which its members are benefitting from the Association's programs. The principal cooperative program set up is the Utility Partnership Program, which was described. Through this program the Association is matching US companies, both electric utilities and gas utilities, with counterparts in Eastern Europe or the former Soviet Union. So far, about 25 partnerships were signed, e.g. in the Czech Republic, in Kazakhstan, in Poland, and in Slovakia. It was estimated that the return to the United States from the investments made by the American government in these Utility Partnership Programs has been well over 100-fold

  14. Lineage-specific positive selection at the merozoite surface protein 1 (msp1 locus of Plasmodium vivax and related simian malaria parasites

    Directory of Open Access Journals (Sweden)

    Kawai Satoru


    Full Text Available Abstract Background The 200 kDa merozoite surface protein 1 (MSP-1 of malaria parasites, a strong vaccine candidate, plays a key role during erythrocyte invasion and is a target of host protective immune response. Plasmodium vivax, the most widespread human malaria parasite, is closely related to parasites that infect Asian Old World monkeys, and has been considered to have become a parasite of man by host switch from a macaque malaria parasite. Several Asian monkey parasites have a range of natural hosts. The same parasite species shows different disease manifestations among host species. This suggests that host immune responses to P. vivax-related malaria parasites greatly differ among host species (albeit other factors. It is thus tempting to invoke that a major immune target parasite protein such as MSP-1 underwent unique evolution, depending on parasite species that exhibit difference in host range and host specificity. Results We performed comparative phylogenetic and population genetic analyses of the gene encoding MSP-1 (msp1 from P. vivax and nine P. vivax-related simian malaria parasites. The inferred phylogenetic tree of msp1 significantly differed from that of the mitochondrial genome, with a striking displacement of P. vivax from a position close to P. cynomolgi in the mitochondrial genome tree to an outlier of Asian monkey parasites. Importantly, positive selection was inferred for two ancestral branches, one leading to P. inui and P. hylobati and the other leading to P. vivax, P. fieldi and P. cynomolgi. This ancestral positive selection was estimated to have occurred three to six million years ago, coinciding with the period of radiation of Asian macaques. Comparisons of msp1 polymorphisms between P. vivax, P. inui and P. cynomolgi revealed that while some positively selected amino acid sites or regions are shared by these parasites, amino acid changes greatly differ, suggesting that diversifying selection is acting species

  15. ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans. (United States)

    Sheehy, Susanne H; Duncan, Christopher J A; Elias, Sean C; Choudhary, Prateek; Biswas, Sumi; Halstead, Fenella D; Collins, Katharine A; Edwards, Nick J; Douglas, Alexander D; Anagnostou, Nicholas A; Ewer, Katie J; Havelock, Tom; Mahungu, Tabitha; Bliss, Carly M; Miura, Kazutoyo; Poulton, Ian D; Lillie, Patrick J; Antrobus, Richard D; Berrie, Eleanor; Moyle, Sarah; Gantlett, Katherine; Colloca, Stefano; Cortese, Riccardo; Long, Carole A; Sinden, Robert E; Gilbert, Sarah C; Lawrie, Alison M; Doherty, Tom; Faust, Saul N; Nicosia, Alfredo; Hill, Adrian V S; Draper, Simon J


    The induction of cellular immunity, in conjunction with antibodies, may be essential for vaccines to protect against blood-stage infection with the human malaria parasite Plasmodium falciparum. We have shown that prime-boost delivery of P. falciparum blood-stage antigens by chimpanzee adenovirus 63 (ChAd63) followed by the attenuated orthopoxvirus MVA is safe and immunogenic in healthy adults. Here, we report on vaccine efficacy against controlled human malaria infection delivered by mosquito bites. The blood-stage malaria vaccines were administered alone, or together (MSP1+AMA1), or with a pre-erythrocytic malaria vaccine candidate (MSP1+ME-TRAP). In this first human use of coadministered ChAd63-MVA regimes, we demonstrate immune interference whereby responses against merozoite surface protein 1 (MSP1) are dominant over apical membrane antigen 1 (AMA1) and ME-TRAP. We also show that induction of strong cellular immunity against MSP1 and AMA1 is safe, but does not impact on parasite growth rates in the blood. In a subset of vaccinated volunteers, a delay in time to diagnosis was observed and sterilizing protection was observed in one volunteer coimmunized with MSP1+AMA1-results consistent with vaccine-induced pre-erythrocytic, rather than blood-stage, immunity. These data call into question the utility of T cell-inducing blood-stage malaria vaccines and suggest that the focus should remain on high-titer antibody induction against susceptible antigen targets.

  16. CHP Partnership Partners (United States)

    Partners of EPA's Combined Heat and Power Partnership include federal, state, and local government agencies and private organizations such as energy users, energy service companies, CHP project developers and consultants, and equipment manufacturers.

  17. Partnership for Peace

    National Research Council Canada - National Science Library

    Penner, Vernon


    Partnership for Peace (PFP) has gotten off to a highly successful start over the past two years with an accelerated growth in membership encompassing the Euro-Atlantic community, the rapid development of its own military...

  18. Urban Waters Partnership (United States)

    Includes information on 14 Federal member agencies for the Urban Waters Federal Partnership and 19 designated urban waters locations and the local stakeholder groups and activities. Content was formerly at

  19. Engineering Capabilities and Partnerships (United States)

    Poulos, Steve


    This slide presentation reviews the engineering capabilities at Johnson Space Center, The presentation also reviews the partnerships that have resulted in successfully designed and developed projects that involved commercial and educational institutions.

  20. Partnership with the customer (United States)

    Trachta, Gregory S.

    This discussion will recount some historical observations about establishing partnerships with the customer. It suggests that such partnerships are established as the natural evolutionary product of a continuous improvement culture. Those are warm, ethereal terms about a topic that some people think already suffers from an excess of hot air. We will focus on some real-world activities and workplace artifacts to show there are substantive concepts behind the TQM buzzwords.

  1. Quantitation of 4-Methyl-4-sulfanylpentan-2-one (4MSP) in Hops by a Stable Isotope Dilution Assay in Combination with GC×GC-TOFMS: Method Development and Application To Study the Influence of Variety, Provenance, Harvest Year, and Processing on 4MSP Concentrations. (United States)

    Reglitz, Klaas; Steinhaus, Martin


    A stable isotope dilution assay was developed for quantitation of 4-methyl-4-sulfanylpentan-2-one (4MSP) in hops. The approach included the use of 4-( 13 C)methyl-4-sulfanyl(1,3,5- 13 C 3 )pentan-2-one as internal standard, selective isolation of hop thiols by mercurated agarose, and GC×GC-TOFMS analysis. Application of the method to 53 different hop samples revealed 4MSP concentrations between <1 and 114 μg/kg. Notably high concentrations were associated with United States varieties such as Citra, Eureka, Simcoe, and Apollo, whereas 4MSP was absent from traditional German and English varieties. Further experiments showed that besides the variety, also harvest year and storage vitally influenced 4MSP concentrations, whereas the impact of provenance was less pronounced. Hop processing such as drying and pelletizing had only a minor impact on 4MSP concentrations. Like the majority of other hop volatiles, 4MSP is predominantly located in the lupulin glands.

  2. The Pennsylvania Academy for the Profession of Teaching; Rural Fellowship Program: A Science Curriculum Development Partnership. Project "Prepare Them for the Future." (United States)

    Beisel, Raymond W.

    This report describes development of the "Prepare Them for the Future" project, a K-3 activity-oriented science curriculum. The program, funded through two grants, was driven by the need to boost the distressed labor-based economy in rural western Pennsylvania. Data showed a drop of 1,100 coal-mining jobs between 1980 and 1986 in Indiana…

  3. The software design of multi-branch, multi-point remote monitoring system for temperature measurement based on MSP430 and DS18B20

    International Nuclear Information System (INIS)

    Yu Jun; Yan Yu


    This paper present that the system can acquire the remote temperature measurement data of 40 monitoring points, through the RS-232 serial port and the Intranet. System's hardware is consist of TI's MSP430F149 mixed-signal processor and UA7000A network module. Using digital temperature sensor DS18B20, the structure is simple and easy to expand, the sensors directly send out the temperature data, MSP430F149 has the advantage of ultra-low-power and high degree of integration. Using msp430F149, the multi-branch multi-point temperature measurement system is powerful, simple structure, high reliability, strong anti-interference capability. The client software is user-friendly and easy to use, it is designed in Microsoft Visual C+ +6.0 environment. The monitoring system is able to complete a total of 4 branches of the 40-point temperature measurements in real-time remote monitoring. (authors)

  4. Milk fat globule-epidermal growth factor-factor VIII-derived peptide MSP68 is a cytoskeletal immunomodulator of neutrophils that inhibits Rac1. (United States)

    Hendricks, Louie; Aziz, Monowar; Yang, Weng-Lang; Nicastro, Jeffrey; Coppa, Gene F; Symons, Marc; Wang, Ping


    Prolonged neutrophil infiltration leads to exaggerated inflammation and tissue damage during sepsis. Neutrophil migration requires rearrangement of their cytoskeleton. Milk fat globule-epidermal growth factor-factor VIII-derived short peptide 68 (MSP68) has recently been shown to be beneficial in sepsis-induced tissue injury and mortality. We hypothesize that MSP68 inhibits neutrophil migration by modulating small GTPase Rac1-dependent cytoskeletal rearrangements. Bone marrow-derived neutrophils (BMDNs) or whole lung digest isolated neutrophils were isolated from 8 to 10 wk old C57BL/6 mice by Percoll density gradient centrifugation. The purity of BMDN was verified by flow cytometry with CD11b/Gr-1 staining. Neutrophils were stimulated with N-formylmethionine-leucine-phenylalanine (f-MLP) (10 nM) in the presence or absence of MSP68 at 10 nM or cecal ligation and puncture (CLP) was used to induce sepsis, and MSP68 was administered at 1 mg/kg intravenously. Cytoskeletal organization was assessed by phalloidin staining, followed by analysis using fluorescence microscopy. Activity of the Rac1 GTPase in f-MLP or CLP-activated BMDN in the presence or absence of MSP68 was assessed by GTPase enzyme-linked immunosorbent assay. Mitogen-activated protein (MAP) kinase activity was determined by western blot densitometry. BMDN treatment with f-MLP increased cytoskeletal remodeling as revealed by the localization of filamentous actin to the periphery of the neutrophil. By contrast, cells pretreated with MSP68 had considerably reduced filamentous actin polymerization. Cytoskeletal spreading is associated with the activation of the small GTPase Rac1. We found BMDN-treated with f-MLP or that were exposed to sepsis by CLP had increased Rac1 signaling, whereas the cells pretreated with MSP68 had significantly reduced Rac1 activation (P Rac1-MAP kinase-mediated neutrophil motility. Thus, MSP68 is a novel therapeutic candidate for regulating inflammation and tissue damage caused

  5. Early Opportunities Research Partnership Between Howard University, University of Maryland Baltimore County and NASA Goddard for Engaging Underrepresented STEM Students in Earth and Space Sciences (United States)

    Misra, P.; Venable, D. D.; Hoban, S.; Demoz, B.; Bleacher, L.; Meeson, B. W.; Farrell, W. M.


    Howard University, University of Maryland Baltimore County and NASA Goddard Space Flight Center (GSFC) are collaborating to engage underrepresented STEM students and expose them to an early career pathway in NASA-related Earth & Space Science research. The major goal is to instill interest in Earth and Space Science to STEM majors early in their academic careers, so that they become engaged in ongoing NASA-related research, motivated to pursue STEM careers, and perhaps become part of the future NASA workforce. The collaboration builds on a program established by NASA's Dynamic Response of the Environments of Asteroids, the Moon and the moons of Mars (DREAM2) team to engage underrepresented students from Howard in summer internships. Howard leveraged this program to expand via NASA's Minority University Research and Education Project (MUREP) funding. The project pairs Howard students with GSFC mentors and engages them in cutting-edge Earth and Space Science research throughout their undergraduate tenure. The project takes a multi-faceted approach, with each year of the program specifically tailored to each student's strengths and addressing their weaknesses, so that they experience a wide array of enriching research and professional development activities that help them grow both academically and professionally. During the academic year, the students are at Howard taking a full load of courses towards satisfying their degree requirements and engaging in research with their GSFC mentors via regular telecons, e-mail exchanges, video chats & on an average one visit per semester to GSFC for an in-person meeting with their research mentor. The students extend their research with full-time summer internships at GSFC, culminating in a Capstone Project and Senior Thesis. As a result, these Early Opportunities Program students, who have undergone rigorous training in the Earth and Space Sciences, are expected to be well-prepared for graduate school and the NASA workforce.


    Energy Technology Data Exchange (ETDEWEB)

    Susan M. Capalbo


    include Wyoming in much of the GIS data sets, analysis, and related materials. The deliverables are discussed in the following sections and greater details are provided in the materials that are attached to this report. In August 2004, a presentation was made to Pioneer Hi-Bred, discussing the Partnership and the synergies with terrestrial sequestration, agricultural industries, and ongoing, complimentary USDA efforts. The Partnership organized a Carbon session at the INRA 2004 Environmental and Subsurface Science Symposium in September 2004; also in September, a presentation was made to the Wyoming Carbon Sequestration Advisory Committee, followed up with a roundtable discussion.

  7. Strengthening STEM Education through Community Partnerships. (United States)

    Lopez, Colleen A; Rocha, Jon; Chapman, Matthew; Rocha, Kathleen; Wallace, Stephanie; Baum, Steven; Lawler, Brian R; Mothé, Bianca R


    California State University San Marcos (CSUSM) and San Marcos Elementary Schools have established a partnership to offer a large-scale community service learning opportunity to enrich science curriculum for K-5 students. It provides an opportunity for science, technology, engineering, and math (STEM) majors to give back to the community, allowing them to experience teaching in an elementary classroom setting, in schools that lack the resources and science instructor specialization needed to instill consistent science curricula. CSUSM responded to this need for more STEM education by mobilizing its large STEM student body to design hands-on, interactive science lessons based on Next Generation Science Standards (NGSS). Since 2012, the program has reached out to over four thousand K-5 students, and assessment data have indicated an increase in STEM academic performance and interest.

  8. The MECA Payload as a Dust Analysis Laboratory on the MSP 2001 Lander (United States)

    Marshall, J.; Anderson, M.; Buehler, M.; Frant, M.; Fuerstenau, S.; Hecht, M.; Keller, U.; Markiewicz, W.; Meloy, T.; Pike, T.


    In a companion abstract, the "Mars Environmental Compatibility Assessment" (MECA) payload for Mars Surveyor Program 2001 (MSP 2001) is described in terms of its capabilities for addressing exobiology on Mars. Here we describe how the same payload elements perform in terms of gathering data about surface dust on the planet. An understanding of the origin and properties of dust is important to both human exploration and planetary geology. The MECA instrument is specifically designed for soil/dust investigations: it is a multifunctional laboratory equipped to assess particulate properties with wet chemistry, camera imagery, optical microscopy (potentially with LTV fluorescence capability), atomic force microscopy (AFM; potentially with mineral-discrimination capabilities), electrometry, active & passive external materials-test panels, mineral hardness testing, and electrostatic & magnetic materials testing. Additionally, evaluation of soil chemical and physical properties as a function of depth down to about 50 cm will be facilitated by the Lander/MECA robot arm on which the camera (RAC) and electrometer are mounted. Types of data being sought for the dust include: (1) general textural and grain-size characterization of the soil as a whole --for example, is the soil essentially dust with other components or is it a clast-supported material in which dust resides only in the clast interstices, (2) size frequency distribution for dust particles in the range 0.01 to 10.00 microns, (3) particle-shape distribution of the soil components and of the fine dust fraction in particular, (4) soil fabric such as grain clustering into clods, aggregates, and cemented/indurated grain amalgamations, as well as related porosity, cohesiveness, and other mechanical soil properties, (5) cohesive relationship that dust has to certain types of rocks and minerals as a clue to which soil materials may be prime hosts for dust "piggybacking", (6) particle, aggregate, and bulk soil electrostatic

  9. 7 CFR 1400.204 - Limited partnerships, limited liability partnerships, limited liability companies, corporations... (United States)


    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Limited partnerships, limited liability partnerships..., limited liability partnerships, limited liability companies, corporations, and other similar legal entities. (a) A limited partnership, limited liability partnership, limited liability company, corporation...

  10. Direct Detection of Unnatural DNA Nucleotides dNaM and d5SICS using the MspA Nanopore.

    Directory of Open Access Journals (Sweden)

    Jonathan M Craig

    Full Text Available Malyshev et al. showed that the four-letter genetic code within a living organism could be expanded to include the unnatural DNA bases dNaM and d5SICS. However, verification and detection of these unnatural bases in DNA requires new sequencing techniques. Here we provide proof of concept detection of dNaM and d5SICS in DNA oligomers via nanopore sequencing using the nanopore MspA. We find that both phi29 DNA polymerase and Hel308 helicase are capable of controlling the motion of DNA containing dNaM and d5SICS through the pore and that single reads are sufficient to detect the presence and location of dNaM and d5SICS within single molecules.

  11. Los complejos Chaperonina(MSP63inducen anticuerpos de reacciones cruzadas, bactericidas y opsonofagocítica.

    Directory of Open Access Journals (Sweden)

    Juan Marzoa


    Full Text Available Alteration of the native structure of antigens can lead to the loss of protective epitopes. Our previous results showed that separation of the meningococcal outer membrane proteins in native conditions revealed the existence of protein complexes that could be relevant for the development of new vaccine formulations. The aim of this work was to analyse the immunogenic characteristics of a highly conserved 700 kDa chaperonin complex (CxChap detected and purified by using high resolution clear native electrophoresis. Analysis of the anti-CxChap serum by Western-blotting revealed the presence of antibodies against the MSP63 but also against the macrophage infectivity potentiator-like protein (MIP, which is coopurified with the chaperonin complex. Antibodies raised by immunisation with CxChap chaperonin complex show bactericidal and opsonophagocytic activity.

  12. Partnership for the future

    International Nuclear Information System (INIS)

    Wilson, R.I.


    The benefits of partnerships in the profitable exploration, development, and management of the world's hydrocarbon resources are discussed. A unique period in history is being experienced in the oil and gas industry. Over the next decade, all of the participants will be faced with a number of opportunities and challenges. No longer will having technical expertise or control of vast resources alone create wealth for a company or country. Long-term profitability will result from decisions and policies made by the owners of these assets. Prudent, efficient, and profitable management of resources through partnership will benefit both parties and enrich the standard of living for future generations

  13. The Partnership of Public Health and Anthropology. (United States)

    Jelenc, Marjetka


    Public health focuses on health of the population and it is concerned with threats to health based on population health analysis. Anthropology covers most aspects that concern human beings. Both sciences converge on community and this fact represents a foundation for the partnership between public health and anthropology. Biological/medical anthropology is one of the highly developed fi elds of anthropology and the most important for public health.

  14. Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana

    DEFF Research Database (Denmark)

    Amoah, L. E.; Nuvor, S. V.; Obboh, E. K.


    Background: Plasmodium falciparum genetic diversity and multiplicity of infection (MOI) are parasite features that have been suggested to influence the acquisition of protective immunity against malaria. This study sought to assess the relationship between MOI and parasite density (PD) in malaria...... and adults diagnosed with uncomplicated P. falciparum malaria. Microscopy was used to estimate P. falciparum parasite density and polymerase chain reaction (PCR) amplification of the polymorphic regions of msp1 (PF3D7-0930300) and msp2 (PF3D7-0206800) was used for parasite genotyping and MOI determination....... The geometric mean (GM) for MOI determined by both msp1 and msp2 genotyping was 1.3 for the entire population and was generally higher in children than in adults. Seropositivity was estimated at 67 and 63% for GLURP(R0) and MSP3 antibodies, respectively, and antibody titers were negatively correlated...

  15. Green Power Partnership Eligible Organizations (United States)

    The U.S. EPA's Green Power Partnership is a voluntary partnership program designed to reduce the environmental impact of electricity generation by promoting renewable energy. Many different types of organizations are eligible to become Partners.

  16. New Partnerships for Sustainability (NEPSUS)

    DEFF Research Database (Denmark)

    Ponte, Stefano; Noe, Christine; Kweka, Opportuna

    New and more complex partnerships are emerging to address the sustainability of natural resource use in developing countries. These partnerships variously link donors, governments, community-based organizations, non-governmental organizations (NGOs), business, certification agencies and other...

  17. Benefits of Green Power Partnership (United States)

    The U.S. EPA's Green Power Partnership is a voluntary partnership program designed to reduce the environmental impact of electricity generation by promoting renewable energy. Learn about the benefits of becoming a Green Power Partner.

  18. Immunogenicity of a virosomally-formulated Plasmodium falciparum GLURP-MSP3 chimeric protein-based malaria vaccine candidate in comparison to adjuvanted formulations

    DEFF Research Database (Denmark)

    Tamborrini, Marco; Stoffel, Sabine A; Westerfeld, Nicole


    In clinical trials, immunopotentiating reconstituted influenza virosomes (IRIVs) have shown great potential as a versatile antigen delivery platform for synthetic peptides derived from Plasmodium falciparum antigens. This study describes the immunogenicity of a virosomally-formulated recombinant ...... fusion protein comprising domains of the two malaria vaccine candidate antigens MSP3 and GLURP....

  19. Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers

    DEFF Research Database (Denmark)

    Turner, Louise; Wang, Christian W; Lavstsen, Thomas


    Antibodies to polymorphic antigens expressed during the parasites erythrocytic stages are important mediators of protective immunity against P. falciparum malaria. Therefore, polymorphic blood stage antigens like MSP3, EBA-175 and GLURP and variant surface antigens PfEMP1 and RIFIN are considered...

  20. Safety and immunogenicity of the malaria vaccine candidate MSP3 long synthetic peptide in 12-24 months-old Burkinabe children.

    NARCIS (Netherlands)

    Sirima, S.B.; Tiono, A.B.; Diarra, A.; Ouedraogo, A.L.; Yaro, J.B.; Ouedraogo, E.; Gansane, A.; Bougouma, E.C.; Konate, A.T.; Kabore, Y.; Traore, A.; Roma, C.; Soulama, I.; Luty, A.J.F.; Cousens, S.; Nebie, I.


    BACKGROUND: A Phase Ia trial in European volunteers of the candidate vaccine merozoite surface protein 3 (MSP3), a Plasmodium falciparum blood stage membrane, showed that it induces biologically active antibodies able to achieve parasite killing in vitro, while a phase Ib trial in semi-immune adult

  1. Regulatory competition in partnership law.


    Siems, Mathias


    Regulatory competition in company law has been extensively debated in the last few decades, but it has rarely been discussed whether there could also be regulatory competition in partnership law. This article fills this gap. It addresses the partnership law of the US, the UK, Germany, and France, and presents empirical data on the different types of partnerships and companies established in these jurisdictions. The main focus is on the use of a limited liability partnership (LLP) outside its ...

  2. Small public private partnerships

    DEFF Research Database (Denmark)

    Koch, Christian; Jensen, Jesper Ole


    Public Private Partnerships (PPP) are frequently mobilized as a purchasing form suitable for large infrastructure projects. And it is commonly assumed that transaction costs linked to the establishment of PPP make them prohibitive in small sizes. In a Danish context this has been safeguarded by t...

  3. Managing Movement as Partnership (United States)

    Kimbrell, Sinead


    The associate director of education at Hubbard Street Dance Chicago recounts her learning and teaching through managing the Movement as Partnership program. Included are detailed descriptions of encounters with teachers and students as they create choreography reflective of their inquiry into integrating dance and literacy arts curriculum in the…

  4. Public private partnerships

    NARCIS (Netherlands)

    Miranda Sarmento, J.J.


    Public-private partnerships (PPPs) are increasing in number worldwide and are used to build and manage large public infrastructure projects. In PPPs, the private sector plays a role in developing and maintaining public infrastructure and services, which is usually a public sector responsibility.

  5. Partnerships for optimizing organizational flexibility (United States)

    Louis Poliquin


    For the purpose of this conference, I was asked to discuss partnerships in general. We will first review the reasons that bring organizations to enter into a collaborative agreement, then provide examples of different types of partnerships, discuss some factors that seem to explain the success of partnerships, and review important points to consider before preparing...

  6. Strategic Partnerships in Higher Education (United States)

    Ortega, Janet L.


    The purpose of this study was to investigate the impacts of strategic partnerships between community colleges and key stakeholders; to specifically examine strategic partnerships; leadership decision-making; criteria to evaluate strategic partnerships that added value to the institution, value to the students, faculty, staff, and the local…

  7. Solution structure of a Plasmodium falciparum AMA-1/MSP 1 chimeric protein vaccine candidate (PfCP-2.9 for malaria

    Directory of Open Access Journals (Sweden)

    Jin Changwen


    Full Text Available Abstract Background The Plasmodium falciparum chimeric protein PfCP-2.9 is a promising asexual-stage malaria vaccine evaluated in clinical trials. This chimeric protein consists of two cysteine-rich domains: domain III of the apical membrane antigen 1 (AMA-1 [III] and the C-terminal region of the merozoite surface protein 1 (MSP1-19. It has been reported that the fusion of these two antigens enhanced their immunogenicity and antibody-mediated inhibition of parasite growth in vitro. Methods The 15N-labeled and 13C/15N-labeled PfCP-2.9 was produced in Pichia pastoris for nuclear magnetic resonance (NMR structure analysis. The chemical shift assignments of PfCP-2.9 were compared with those previously reported for the individual domains (i.e., PfAMA-1(III or PfMSP 1-19. The two-dimensional spectra and transverse relaxation rates (R2 of the PfMSP1-19 alone were compared with that of the PfCP-2.9. Results Confident backbone assignments were obtained for 122 out of 241 residues of PfCP-2.9. The assigned residues in PfCP-2.9 were very similar to those previously reported for the individual domains. The conformation of the PfMSP1-19 in different constructs is essentially the same. Comparison of transverse relaxation rates (R2 strongly suggests no weak interaction between the domains. Conclusions These data indicate that the fusion of AMA-1(III and MSP1-19 as chimeric protein did not change their structures, supporting the use of the chimeric protein as a potential malaria vaccine.

  8. Assessing the effectiveness of Multi-Sector Partnerships to manage droughts: The case of the Jucar river basin (United States)

    Carmona, María.; Máñez Costa, María.; Andreu, Joaquín.; Pulido-Velazquez, Manuel; Haro-Monteagudo, David; Lopez-Nicolas, Antonio; Cremades, Roger


    South-east Spain is a drought prone area, characterized by climate variability and water scarcity. The Jucar River Basin, located in Eastern Spain, has suffered many historical droughts with significant socio-economic impacts. For nearly a hundred years, the institutional and non-institutional strategies to cope with droughts have been successful through the development of institutions and partnerships for drought management including multiple actors. In this paper, we show how the creation and institutionalisation of Multi-Sector Partnerships (MSPs) has supported the development of an efficient drought management. Furthermore, we analyze the performance of one of the suggested instruments by the partnership related to drought management in the basin. Two methodologies are used for these purposes. On one hand, the Capital Approach Framework to analyze the effectiveness of the governance processes in a particular partnership (Permanent Drought Commission), which aims to highlight the governance strength and weakness of the MSP for enhancing drought management in the Jucar River Basin. Through a dynamic analysis of the changes that the partnership has undergone over time to successfully deal with droughts, its effectiveness on drought management is demonstrated. On the other hand, an econometric approach is used to analyze the economic efficiency of the emergency drought wells as one of the key drought mitigation measures suggested by the Permanent Drought Commission and implemented. The results demonstrate the potential and efficiency of applying drought wells as mitigation measures (significant reduction of economic losses, around 50 M€ during the drought period, 2005-2008).

  9. Improving refueling outages through partnership

    International Nuclear Information System (INIS)

    Mercado, Angelo L.


    This paper describes an approach to reduce nuclear plant outage duration and cost through partnership. Partnership is defined as a long-term commitment between the utility and the vendor with the objective of achieving shared business goals by maximizing the effectiveness of each party's resources. The elements of an effective partnership are described. Specific examples are given as to how partnership has worked in the effective performance of refueling outages. To gain the full benefits of a partnership, both parties must agree to share information, define the scope early, communicate goals and expectations, and identify boundaries for technical ownership. (author)

  10. Building Climate Literacy Through Strategic Partnerships (United States)

    Turrin, M.; Creyts, T. T.; Bell, R. E.; Meadows, C. A.


    One of the challenges of developing climate science literacy is establishing the relevance of both climate science and climate change at a local community level. By developing partnerships with community-based informal science education providers, we are able to build our climate science and climate change content into existing programs. Employing a systems science approach facilitates these partnerships as our systems science program links with a range of topics, demonstrating the multiple connections between climate, our communities and our daily lives. Merging hands on activities, collaborative projects, and new technology, we encourage learning through doing by engaging participants in active exploration of climate science concepts. Many informal education venues operating locally, from large science museums to small grass-roots community groups, provide ongoing opportunities to connect with students. Through our collaborations we have worked with various types and sizes of non-classroom science providers including: the Intrepid Sea, Air and Space Museum "Greater Opportunities Advancing Leadership and Science" camps for high school girls, Hudson River Park Trust 'Science on the River' events, the annual New York City World Science Festival, and the AAUW's annual STEM Super Scholars Workshops among others. This range of venues has enabled us to reach various ages, backgrounds and interests advancing climate literacy in a number of forums. Major outcomes of these efforts are: (1) Building capacity with community groups: Many local organizations running community programs do not have in-house science expertise. Both science educators and local organization benefit from these collaborations. Science educators and scientists provide up to date climate science information to the community groups while these programs establish strong working relationships between our research and the local community. (2) Developing climate science literacy and lifelong learning: We

  11. Atoms for food - A global partnership

    International Nuclear Information System (INIS)

    Wedekind, L.


    The International Atomic Energy Agency (IAEA) and Food and Agriculture Organization of the United Nations (FAO) have been partners for nearly half a century, contributing to efforts toward shared goals of food security. Their mission - through a Joint Division headquartered at the IAEA in Austria - is to help countries effectively use nuclear science and related technologies for food and agricultural development. Millions of people today look to a better future because of the foresight and longstanding investment of FAO and IAEA Member States in the 'Atoms for Food' partnership. Worldwide, more than 100 countries are working together through the Joint Division to increase their harvests, combat animal and plant diseases and pests, and protect the lands, water resources, and environments on which food and agricultural production depend. This century's stark realities of hunger, poverty, climate change, and environmental degradation bring an unprecedented scale of challenges to the fields of food and agriculture. Action requires the research, expertise, and experience of the FAO/IAEA partnership and other effective alliances worldwide to help countries achieve and sustain higher levels of food security for their people. The two organizations are well matched. FAO brings to the table its comprehensive knowledge and networks on food and agriculture. The IAEA, in turn, contributes technical know-how, specifically in agricultural and related applications of nuclear science and technology. The partnership's potential builds on decades of experience

  12. Euro-Mediterranean Partnership

    DEFF Research Database (Denmark)

    Brach, Juliane


    The EU and 12 countries of the Middle East and North Africa (MENA) engaged in 1995 in the Euro-Mediterranean Partnership (EMP) in political, economic and cultural matters with the aim to foster cooperation, stability and prosperity around the Mediterranean Basin. The Economic and Financial...... and the past performance of the EFP. It analyses the association agreements, economic cooperation and financial assistance, discusses the major obstacles, and outlines the potential of the EFP to shape the European Neighborhood Policy....

  13. Public-Private Partnerships

    DEFF Research Database (Denmark)

    Lehmann, Martin; Jeppesen, S.


    Public-private partnerships in the environmental field have emerged as one option in the pursuit of sustainable development. So-called ‘Green Networks’, ‘Cleaner Production Centres’, ‘Waste Minimisation Clubs’ are among others highlighted as alternatives to governmental regulation. While being...... these initiatives in an institutional framework and suggest how the experiences can be understood in their own rights....

  14. The Global Soil Partnership (United States)

    Montanarella, Luca


    The Global Soil Partnership (GSP) has been established, following an intensive preparatory work of the Food and Agriculture Organization of the United Nations (FAO) in collaboration with the European Commission (EC), as a voluntary partnership coordinated by the FAO in September 2011 [1]. The GSP is open to all interested stakeholders: Governments (FAO Member States), Universities, Research Organizations, Civil Society Organizations, Industry and private companies. It is a voluntary partnership aiming towards providing a platform for active engagement in sustainable soil management and soil protection at all scales: local, national, regional and global. As a “coalition of the willing” towards soil protection, it attempts to make progress in reversing soil degradation with those partners that have a genuine will of protecting soils for our future generations. It openly aims towards creating an enabling environment, despite the resistance of a minority of national governments, for effective soil protection in the large majority of the countries that are genuinely concerned about the rapid depletion of their limited soil resources.

  15. An Innovative Approach to Addressing Childhood Obesity: A Knowledge-Based Infrastructure for Supporting Multi-Stakeholder Partnership Decision-Making in Quebec, Canada

    Directory of Open Access Journals (Sweden)

    Nii Antiaye Addy


    Full Text Available Multi-stakeholder partnerships (MSPs have become a widespread means for deploying policies in a whole of society strategy to address the complex problem of childhood obesity. However, decision-making in MSPs is fraught with challenges, as decision-makers are faced with complexity, and have to reconcile disparate conceptualizations of knowledge across multiple sectors with diverse sets of indicators and data. These challenges can be addressed by supporting MSPs with innovative tools for obtaining, organizing and using data to inform decision-making. The purpose of this paper is to describe and analyze the development of a knowledge-based infrastructure to support MSP decision-making processes. The paper emerged from a study to define specifications for a knowledge-based infrastructure to provide decision support for community-level MSPs in the Canadian province of Quebec. As part of the study, a process assessment was conducted to understand the needs of communities as they collect, organize, and analyze data to make decisions about their priorities. The result of this process is a “portrait”, which is an epidemiological profile of health and nutrition in their community. Portraits inform strategic planning and development of interventions, and are used to assess the impact of interventions. Our key findings indicate ambiguities and disagreement among MSP decision-makers regarding causal relationships between actions and outcomes, and the relevant data needed for making decisions. MSP decision-makers expressed a desire for easy-to-use tools that facilitate the collection, organization, synthesis, and analysis of data, to enable decision-making in a timely manner. Findings inform conceptual modeling and ontological analysis to capture the domain knowledge and specify relationships between actions and outcomes. This modeling and analysis provide the foundation for an ontology, encoded using OWL 2 Web Ontology Language. The ontology is developed

  16. From agenda-setting to implementation: The role of multisectoral partnerships in addressing urban climate risks (United States)

    Surminski, Swenja; Leck, Hayley


    Multisectoral partnerships (MSPs) form an increasingly popular and important part of the global climate and disaster risk governance landscape, but the literature offers little critical investigation of this phenomenon. In particular it remains unclear how MSPs can support the transition from agenda setting to implementation in response to multiple current and future pressures threatening the resilience of cities. Through the lens of the London Climate Change Partnership (LCCP) and drawing from other MSP examples, this paper investigates the scope for MSPs to enhance climate adaptation in an urban context. Our paper has two main aims: to expand understanding of the role of MSPs in the adaptation decision process in the context of the wider governance literature, and to shed some light on the complexities of transitioning through that process. To clarify the role of a MSP we propose a distinction between "first generation" and "second generation" MSPs, illustrating the progression from agenda-setting to implementation: "first generation" MSPs are focused on agenda setting and knowledge sharing in order to support decision makers, while "second generation" MSPs are aimed at implementing solutions. We consider this distinction from the perspective of the individual members and their perceptions, motivations, and expectations. We find that the dynamic nature of urban adaptation with a shifting focus from initial agenda setting toward the implementation of actions presents challenges for existing MSPs, particularly such long-established ones like the LCCP. Our investigation shows that "first generation" MSPs can play important roles in agenda setting, but finds little evidence of "second generation" MSPs achieving implementation.

  17. Public-Private Partnerships and Sustainable Regional Innovation Systems

    DEFF Research Database (Denmark)

    Lehmann, Martin; Christensen, Per; Johnson, Bjørn

    -private partnerships. The role of universities if and when actively participating in ‘life outside the ivory tower’ is addressed. These partnerships are also discussed in a regional context. With point of departure in innovation theory, we combine ‘sustainable development’ with the Regional System of Innovation...... approach to propose a new concept – Sustainable Regional Innovation System – in which regional initiatives such as Public-Private(-Academic) Partnerships play an integrated role, not least in the context of ‘learning and innovation for sustainable development’. Two cases are presented to underline...... be playing in public-private partnerships for sustainable development, and the links and benefits this may provide towards universities fulfilling their first (science) and second (education) missions. In this paper, the first part is dedicated to the discussion and clarification of the concept of public...

  18. A high frequency MspI RFLP at the human vitamin D binding protein (hDBP) locus

    Energy Technology Data Exchange (ETDEWEB)

    Ray, K; Cooke, N E [Univ. of Pennsylvania, Philadelphia (USA)


    A nearly full-length cDNA encoding the human vitamin D binding protein (hDBP), also known as Gc-globulin, was isolated from a human liver cDNA expression library. This 1.73 kb cDNA was digested with EcoRI and the 5{prime}, 140 bp fragment of the cDNA, subcloned into plasmid SP65 (phDBP140), was used as probe. MspI identifies a two allele polymorphism with either a band at 12 kb or a band at 5 kb. The frequency was estimated from a study of 24 unrelated North American Caucasians. The hDBP gene has been localized to chromosome 4 using a cDNA probe and a panel of rodent X human somatic cell hybrids. It was sublocalized to 4q11-q13 by in situ hybridization. Co-dominant autosomal segregation of the polymorphic alleles has been observed in two informative families (20 individuals). With overexposure of the autoradiograph two faint variant bands are seen at 17 kb and 13.5 kb which appear to cosegregate with the 12 kb band and the 5 kb band respectively.

  19. A mutation in human VAP-B--MSP domain, present in ALS patients, affects the interaction with other cellular proteins. (United States)

    Mitne-Neto, M; Ramos, C R R; Pimenta, D C; Luz, J S; Nishimura, A L; Gonzales, F A; Oliveira, C C; Zatz, M


    Amyotrophic Lateral Sclerosis (ALS) is the most common adult-onset Motor Neuron Disease (MND), characterized by motor neurons death in the cortex, brainstem and spinal cord. Ten loci linked to Familial ALS have been mapped. ALS8 is caused by a substitution of a proline by a serine in the Vesicle-Associated Membrane Protein-Associated protein-B/C (VAP-B/C). VAP-B belongs to a highly conserved family of proteins implicated in Endoplasmic Reticulum-Golgi and intra-Golgi transport and microtubules stabilization. Previous studies demonstrated that the P56S mutation disrupts the subcellular localization of VAP-B and that this position would be essential for Unfolded Protein Response (UPR) induced by VAP-B. In the present work we expressed and purified recombinant wild-type and P56S mutant VAP-B-MSP domain for the analysis of its interactions with other cellular proteins. Our findings suggest that the P56S mutation may lead to a less stable interaction of this endoplasmic reticulum protein with at least two other proteins: tubulin and GAPDH. These two proteins have been previously related to other forms of neurodegenerative diseases and are potential key points to understand ALS8 pathogenesis and other forms of MND. Understanding the role of these protein interactions may help the treatment of this devastating disease in the future.

  20. Mutual benefits in academic-service partnership: An integrative review. (United States)

    Sadeghnezhad, Maliheh; Heshmati Nabavi, Fatemeh; Najafi, Fereshteh; Kareshki, Hossein; Esmaily, Habibollah


    Academic and service institutions involve with many challenges. Partnership programs are a golden opportunity to achieve mutual benefits to overcome these challenges. Identifying mutual benefits is the cornerstone of forming a successful partnership and guarantee to its continuity. There are definitions and instances of mutual benefits in the literature related to partnership programs, but there is no coherent evidence and clear picture of these benefits. This study is conducted to identify mutual benefits in academic-service partnership by analyzing the definitions and instances of it in the literature. An integrative review of key papers regarding mutual benefits in academic-service partnership was undertaken. This review was guided by the framework described by Whittemore and Knafl. Search of the following databases was conducted: MEDLINE, ERIC, Google Scholar, Emerald Insight and Science Direct. The search terms were mutual benefits, mutual gains, mutual interest, mutual expectations, mutual goals, mutual demand, partnership, collaboration, academic-service partnership and academic service collaboration. Cooper's five-stage integrative review method was used. Quality evaluation of articles was conducted. Data were abstracted from included articles. The analysis was conducted based on the qualitative content analysis of the literature suggested by Zhang and Wildemuth. 28 articles were included in this review. Mutual benefits are described in four categories include: synergy in training and empowerment of human resources, education improvement, access to shared resources, facilitate production and application of beneficial knowledge into practice. Mutual benefits in the academic-service partnership include a range of goals, interests, expectations, and needs of partner organizations that is achievable and measurable through joint planning and collaboration. We suggest academic and service policymakers to consider these benefits in the planning and evaluating

  1. Civil partnerships five years on. (United States)

    Ross, Helen; Gask, Karen; Berrington, Ann


    The Civil Partnership Act 2004, which came into force in December 2005 allowing same-sex couples in the UK to register their relationship for the first time, celebrated its fifth anniversary in December 2010. This article examines civil partnership in England and Wales, five years on from its introduction. The characteristics of those forming civil partnerships between 2005 and 2010 including age, sex and previous marital/civil partnership status are examined. These are then compared with the characteristics of those marrying over the same period. Further comparisons are also made between civil partnership dissolutions and divorce. The article presents estimates of the number of people currently in civil partnerships and children of civil partners. Finally the article examines attitudes towards same-sex and civil partner couples both in the UK and in other countries across Europe.

  2. A novel merozoite surface antigen of Plasmodium falciparum (MSP-3 identified by cellular-antibody cooperative mechanism antigenicity and biological activity of antibodies

    Directory of Open Access Journals (Sweden)

    Claude Oeuvray


    Full Text Available We report the identification of a 48kDa antigen targeted by antibodies which inhibit Plasmodium falciparum in vitro growth by cooperation with blood monocytes in an ADCI assay correlated to the naturally acquired protection. This protein is located on the surface of the merozoite stage of P. falciparum, and is detectable in all isolates tested. Epidemiological studies demonstrated that peptides derived from the amino acid sequence of MSP-3 contain potent B and T-cell epitopes recognized by a majority of individuals living in endemic areas. Moreover human antibodies either purified on the recombinant protein, or on the synthetic peptide MSP-3b, as well as antibodies raised in mice, were all found to promote parasite killing mediated by monocytes.

  3. MspI and PvuII polymorphisms in the Na,K-ATPase. beta. subunit gene ATP1B1

    Energy Technology Data Exchange (ETDEWEB)

    Shull, M.M.; Pugh, D.G.; Lane, L.K.; Lingrel, J.B. (Univ. of Cincinnati College of Medicine, OH (USA))


    ATP1B HH1.2 is a 1.2 kb HindIII fragment from the 3{prime} portion of the human Na,K-ATPase {beta} subunit gene, ATP1B1. MspI identifies a two allele polymorphism (M1: 6.7 kb, M2: 5.3 kb). PvuII also detects a two-allele polymorphism (P1: 5.1 kb, P2: 4.7 kb). ATP1B1 has been assigned to chromosome 1q by somatic cell hybrid analysis. Codominant segregation of the MspI RFLP was observed in one two-generation family (5 individuals). Codominant segregation of the PvuII RFLP was observed in a two-generation (8 individuals) and a three-generation (12 individuals) family.

  4. A Competitive Partnership Formation Process


    Andersson, Tommy; Gudmundsson, Jens; Talman, Adolphus; Yang, Zaifu


    A group of heterogeneous agents may form partnerships in pairs. All single agents as well as all partnerships generate values. If two agents choose to cooperate, they need to specify how to split their joint value among one another. In equilibrium, which may or may not exist, no agents have incentives to break up or form new partnerships. This paper proposes a dynamic competitive adjustment process that always either finds an equilibrium or exclusively disproves the existence of any equilibri...

  5. Immunogenicity of a virosomally-formulated Plasmodium falciparum GLURP-MSP3 chimeric protein-based malaria vaccine candidate in comparison to adjuvanted formulations

    Directory of Open Access Journals (Sweden)

    Tamborrini Marco


    Full Text Available Abstract Background In clinical trials, immunopotentiating reconstituted influenza virosomes (IRIVs have shown great potential as a versatile antigen delivery platform for synthetic peptides derived from Plasmodium falciparum antigens. This study describes the immunogenicity of a virosomally-formulated recombinant fusion protein comprising domains of the two malaria vaccine candidate antigens MSP3 and GLURP. Methods The highly purified recombinant protein GMZ2 was coupled to phosphatidylethanolamine and the conjugates incorporated into the membrane of IRIVs. The immunogenicity of this adjuvant-free virosomal formulation was compared to GMZ2 formulated with the adjuvants Montanide ISA 720 and Alum in three mouse strains with different genetic backgrounds. Results Intramuscular injections of all three candidate vaccine formulations induced GMZ2-specific antibody responses in all mice tested. In general, the humoral immune response in outbred NMRI mice was stronger than that in inbred BALB/c and C57BL/6 mice. ELISA with the recombinant antigens demonstrated immunodominance of the GLURP component over the MSP3 component. However, compared to the Al(OH3-adjuvanted formulation the two other formulations elicited in NMRI mice a larger proportion of anti-MSP3 antibodies. Analyses of the induced GMZ2-specific IgG subclass profiles showed for all three formulations a predominance of the IgG1 isotype. Immune sera against all three formulations exhibited cross-reactivity with in vitro cultivated blood-stage parasites. Immunofluorescence and immunoblot competition experiments showed that both components of the hybrid protein induced IgG cross-reactive with the corresponding native proteins. Conclusion A virosomal formulation of the chimeric protein GMZ2 induced P. falciparum blood stage parasite cross-reactive IgG responses specific for both MSP3 and GLURP. GMZ2 thus represents a candidate component suitable for inclusion into a multi-valent virosomal

  6. CYP1A1 MspI Polymorphism and Cervical Carcinoma Risk in the Multi-Ethnic Population of Malaysia: a Case-Control Study. (United States)

    Tan, Yee Hock; Sidik, Shiran Mohd; Syed Husain, Sharifah Noor Akmal; Lye, Munn Sann; Chong, Pei Pei


    Tobacco smoking is considered a risk factor for cervical cancer development due to the presence of tobacco based carcinogenic metabolites in cervical cells of female smokers. In this study, we investigated the role of the T3801C (MspI) polymorphism of CYP1A1, a gene encoding an enzyme necessary for the initiation of tobacco based carcinogen metabolism, on cervical cancer risk. The T to C substitution may alter CYP1A1 activities, potentially elevating cervical cancer risk. Since results of gene-disease association studies vary according to the study population, the multi-ethnic population of Malaysia provides an excellent representative cohort for identifying and comparing the cervical cancer risk among the 3 major ethnics in Southeast Asia in relation to CYP1A1 MspI polymorphism. A total of 195 Thin Prep Pap smear samples from HPV negative and cancer free females were randomly selected as controls while 106 formalin fixed paraffin embedded samples from females with invasive cervical cancer were randomly selected for the cases group. The polymorphisms were identified using restriction fragment length polymorphism (RFLP) PCR. We found no significant associations between CYP1A1 MspI polymorphism and cervical cancer in the general Malaysian female population. However, upon ethnic stratification, the variant C/C genotype was significantly associated with a 4.66-fold increase in cervical cancer risk in Malay females (95% CI= 1.21-17.9; p=0.03). No significant association was observed in the Chinese and Indian females. Additionally, there were no significant associations in the dominant model and allele frequency model analysis in both the general and ethnically stratified female population of Malaysia. Our findings suggest that the C/C genotype of CYP1A1 MspI polymorphism is associated with the development of cervical carcinoma in the Malay females of Malaysia.

  7. Strengthening partnerships among Africa's science granting ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The project will support regional training courses and on-site coaching to strengthen the capacity of participating councils to design and manage collaborative agreements. It will also co-fund demand-led collaborative research projects in selected areas of interest to the private sector. Sharing of evidence, lessons learned ...

  8. Public-private Partnerships

    DEFF Research Database (Denmark)

    Hodge, Graeme A.; Greve, Carsten; Boardman, Anthony E.


    more to seeking economic growth and political success rather than demonstrating ‘one-best-way’ to deliver efficient infrastructure. This article traces where the infrastructure PPP idea has come from and what it is now becoming. It takes a global perspective and places Australian and international...... experience in this context, particularly through the global financial crisis. It concludes that PPP can become an integrated part of infrastructure development around the world, assuming learning occurs from past experience. It presents several lessons on deepening partnerships; on the multiplicity...

  9. The Eastern Partnership

    DEFF Research Database (Denmark)

    Nielsen, Kristian L.; Vilson, Maili


    When the EU launched the Eastern Partnership (EaP) in 2009, it did so with much rhetoric about projecting its soft power into Eastern Europe. Yet today, the EU's soft power project seems to have stalled, with developments in the region being less than favourable. This article argues that the EaP...... essentially replicated the main weaknesses of the European Neighbourhood Policy, by offering too little incentive and support to the partners, rendering both conditionality and soft power ineffective as tools for milieu shaping. In promoting the EaP as a policy of soft power, the EU has once again forgotten...

  10. 31 CFR 306.87 - Partnerships (including nominee partnerships). (United States)


    ... (including nominee partnerships). An assignment of a security registered in the name of or assigned to a... appropriate for winding up partnership affairs. In those cases where assignments by or in behalf of all... dissolution. Upon voluntary dissolution, for any jurisdiction where a general partner may not act in winding...


    International Nuclear Information System (INIS)

    Morris, Fred A.; Murray, A.; Dickerson, S.; Tynan, Douglas M.; Rawl, Richard R.; Hoo, Mark S.


    In 2004, Australia, through the Australian Nuclear Science and Technology Organisation (ANSTO) created the Regional Security of Radioactive Sources (RSRS) project and partnered with the U.S. Department of Energy's National Nuclear Security Administration (NNSA) and the International Atomic Energy Agency (IAEA) to form the Southeast Asian Regional Radiological Security Partnership (RRSP). The intent of the RRSP/RSRS partnership is to cooperate with regional neighbors in Southeast Asia to improve the security of their radioactive sources. This Southeast Asian Partnership supports NNSA and IAEA objectives to improve the security of high risk radioactive sources by raising awareness of the need, and developing national programs, to: protect and control such materials; improve the security of such materials and recover and condition the materials no longer in use. To date, agreed upon joint activities have included assistance with the improvement of regulatory infrastructure for the control of radioactive sources, training on the physical protection of radioactive sources, training and assistance with the search, location, identification and securing of orphan radioactive sources and overall assistance with implementing the IAEA Code of Conduct on the Safety and Security of Radioactive Sources. Since the inception of the partnership, ten Southeast Asian nations have participated in a range of activities from receiving general training on the security of radioactive sources to receiving specialized equipment and training to locate orphan or abandoned radioactive sources. By having a shared vision and objectives for radioactive source security in the Southeast Asian region, ANSTO and NNSA have been able to develop a successful partnership which has effectively utilized the technical, financial and political resources of each contributing partner. An example of how this partnership works is the cooperation with the Nuclear Energy Regulatory Agency, Indonesia (BAPETEN) to

  12. Fibronectin gene polymorphisms and clinical manifestations of mixed cryoglobulinemic syndrome: increased risk of lymphoma associated to MspI DD and HaeIII AA genotypes

    Directory of Open Access Journals (Sweden)

    C. Fabro


    Full Text Available Objective: To analyse FN gene polymorphisms in type II mixed cryoglobulinemic syndrome (MCsn, an immune-complex mediated systemic vasculitis linked to hepatitis C virus (HCV infection and characterized by rheumatoid factor (RF positive B-cell proliferation at high risk for the progression into non Hodgkin’s lymphoma (NHL. Methods: Samples from eighty-one patients, with MCsn (type II serum cryoglobulins and clinical signs of vasculitis were studied. Sixthy-five (65/81, 80.3% patients were HCV-positive. Twenty-one (25.9% patients had developed a B-cell NHL during the course of MCsn. Seventy-two patients with HCV-negative and MC-unrelated NHL and 110 healthy blood donors (HBDs were taken as controls. HaeIIIb and MspI FN gene polymorphisms were analysed by PCR and specific restriction enzyme digestions, following reported procedures. Plasma FN levels were analysed by ELISA, whenever possible. Results: HaeIIIb and MspI allele and genotype frequencies did not differ between MCsn patients and HBDs. Of note, the DD-MspI (OR=5.56; CI=1.67-18.51, p=0.0046 and the AA-HaeIIIb (OR=5.54; CI=1.64-18.76, p=0.0066 homozygosis appeared significantly and independently associated with the development of B-cell NHL in MCsn patients, with the HaeIIIb A allele possibly conferring an increased risk of NHL in the general population (OR=1.72, CI=1.128- 2.635, p=0.0133. In contrast, the major vasculitic manifestations, such as peripheral neuropathy, skin ulcers and glomerulonephritis tended to be associated with the counterpart MspI C allele. No association between FN plasma levels and FN genotypes was found. Conclusion: Genotyping for MspI and HaeIIIb FN gene polymorphisms may be clinically relevant to define the predisposition to the major clinical manifestations in MCsn.

  13. Institutions, Partnerships and Institutional Change

    NARCIS (Netherlands)

    J.C.A.C. van Wijk (Jeroen); S.R. Vellema (Sietze); J. van Wijk (Jakomijn)


    markdownabstractOne of the goals of the Partnership Resource Centre (PRC) is to execute evidence-based research and further develop a theoretical framework on the linkages between partnerships and value chain development (ECSAD 2009). Within the PRC Trajectory on Global Value Chains, this goal was

  14. Strategic Partnerships in International Development (United States)

    Treat, Tod; Hartenstine, Mary Beth


    This chapter provides a framework and recommendations for development of strategic partnerships in a variety of cultural contexts. Additionally, this study elucidates barriers and possibilities in interagency collaborations. Without careful consideration regarding strategic partnerships' approaches, functions, and goals, the ability to…

  15. Partnership for Wave Power - Roadmaps

    DEFF Research Database (Denmark)

    Nielsen, Kim; Krogh, Jan; Brodersen, Hans Jørgen

    This Wave Energy Technology Roadmap is developed by the Partnership for Wave Power including nine Danish wave energy developers. It builds on to the strategy [1] published by the Partnership in 2012, a document that describes the long term vision of the Danish Wave Energy sector: “By 2030...

  16. Partnerships for Global Child Health. (United States)

    Steenhoff, Andrew P; Crouse, Heather L; Lukolyo, Heather; Larson, Charles P; Howard, Cynthia; Mazhani, Loeto; Pak-Gorstein, Suzinne; Niescierenko, Michelle L; Musoke, Philippa; Marshall, Roseda; Soto, Miguel A; Butteris, Sabrina M; Batra, Maneesh


    Child mortality remains a global health challenge and has resulted in demand for expanding the global child health (GCH) workforce over the last 3 decades. Institutional partnerships are the cornerstone of sustainable education, research, clinical service, and advocacy for GCH. When successful, partnerships can become self-sustaining and support development of much-needed training programs in resource-constrained settings. Conversely, poorly conceptualized, constructed, or maintained partnerships may inadvertently contribute to the deterioration of health systems. In this comprehensive, literature-based, expert consensus review we present a definition of partnerships for GCH, review their genesis, evolution, and scope, describe participating organizations, and highlight benefits and challenges associated with GCH partnerships. Additionally, we suggest a framework for applying sound ethical and public health principles for GCH that includes 7 guiding principles and 4 core practices along with a structure for evaluating GCH partnerships. Finally, we highlight current knowledge gaps to stimulate further work in these areas. With awareness of the potential benefits and challenges of GCH partnerships, as well as shared dedication to guiding principles and core practices, GCH partnerships hold vast potential to positively impact child health. Copyright © 2017 by the American Academy of Pediatrics.

  17. A competitive partnership formation process

    NARCIS (Netherlands)

    Andersson, T.; Gudmundsson, J.; Talman, A.J.J.

    A group of heterogeneous agents may form partnerships in pairs. All single agents as well as all partnerships generate values. If two agents choose to cooperate, they need to specify how to split their joint value among one another. In equilibrium, which may or may not exist, no agents have

  18. Cross-Sector Partnership Formation

    NARCIS (Netherlands)

    I. Stöteler (Ismaela); S. Reeder (Sabine); R.J.M. van Tulder (Rob)


    textabstractA cross-sector partnership is a collaborative effort in which parties from different societal sectors pool resources to provide solutions to (perceived) common problems. These partnerships are often rather complex because of a number of reasons: (1) they address complex issues, (2) they

  19. A Competitive Partnership Formation Process

    NARCIS (Netherlands)

    Andersson, T.; Gudmundsson, J.; Talman, A.J.J.; Yang, Z.


    A group of heterogenous agents may form partnerships in pairs. All single agents as well as all partnerships generate values. If two agents choose to cooperate, they need to specify how to split their joint value among one another. In equilibrium, which may or may not exist, no agents have

  20. Tradition and Technology. A Magnet School-Museum Partnership. (United States)

    Judd, Michael; Judd, Elizabeth


    Presents a case study of an educational partnership between an Albuquerque magnet elementary school and the New Mexico Museum of Natural History and Science. Descriptions of the school and museum are provided as well as the program's goals, current activities and products, outcomes, and future directions. The Proyecto Futuro program, a multiyear…

  1. Examining the Complexities of School-Museum Partnerships (United States)

    Gupta, Preeti; Adams, Jennifer; Kisiel, James; Dewitt, Jennifer


    We examine the research conducted by Kang, Anderson and Wu by discussing it in a larger context of science museum-school partnerships. We review how the disconnect that exists between stakeholders, the historical and cultural contexts in which formal and informal institutions are situated, and ideas of globalization, mediate the success for…

  2. IDRC-GDN: A Strengthened Partnership for Research Capacity ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC-GDN: A Strengthened Partnership for Research Capacity Building. This project provides core funding to the Global Development Network (GDN) over three years. GDN supports social science researchers in developing and transition countries. Its core mission is to enhance policy-relevant research capacity by ...

  3. Better Together: Expanding Rural Partnerships to Support Families (United States)

    Shaklee, Harriet; Bigbee, Jeri; Wall, Misty


    Chronic shortages of health, social service, and mental health professionals in rural areas necessitate creative partnerships in support of families. Cooperative extension professionals in Family and Consumer Sciences and community health nurses, who can bring critical skills to human services teams, are introduced as trusted professionals in…

  4. Discussions across Borders: A German-American Partnership (United States)

    Zeiser, Pamela A.; Fuchs, Doris; Engelkamp, Stephan


    This article reports on our experiences in a German-American partnership in internationalizing the curriculum. In a globalized world, engaging other cultures and identities as well as understanding global issues and events from other perspectives are important qualifications that allow students to gain different insights in political science. Yet,…

  5. Strengthening Knowledge Co-Production Capacity: Examining Interest in Community-University Partnerships

    Directory of Open Access Journals (Sweden)

    Kathleen P. Bell


    Full Text Available Building successful, enduring research partnerships is essential for improving links between knowledge and action to address sustainability challenges. Communication research can play a critical role in fostering more effective research partnerships, especially those concerned with knowledge co-production processes. This article focuses on community-university research partnerships and factors that influence participation in the co-production process. We identify specific pathways for improving partnership development through a prospective analytical approach that examines community officials’ interest in partnering with university researchers. Using survey responses from a statewide sample of Maine municipal officials, we conduct a statistical analysis of community-university partnership potential to test a conceptual model of partnership interest grounded in natural resource management theory and environmental communication. Our findings both support and advance prior research on collaborations. Results reveal that belief in the helpfulness of the collaborator to solve problems, institutional proximity, familiarity, perceived problem severity and problem type and trust influence interest in developing community-university partnerships. These findings underscore the benefits of proactively assessing partnership potential prior to forming partnerships and the important roles for communication research within sustainability science, especially with regard to strengthening partnership formation and knowledge co-production processes.

  6. A London shop window for PPARC industry partnership successes

    CERN Multimedia

    Neale, R


    The UK Particle Physics and Astronomy Research Council recently held a seminar in London to reveal the results of the impressive work they are doing in fostering partnerships between science and industry. They have many different types of funded programmes, the purpose of all of them is to encourage industry and entrepreneurs to both benefit from and service the requirements of particle physics science and technology (1 page).

  7. The AMTEX Partnership

    Energy Technology Data Exchange (ETDEWEB)

    Lemon, D.K.


    The American Textile Partnership, as its name implies, is a collaborative effort between the DOE national labs and industry-related R&D/educational institutions. The purpose of AMTEX is to promote R&D that enhance the competitiveness of the integrated textile industry (i.e., fibers, textiles, sewn/fabricated products). The industry-related organizations bring a vital perspective of industry needs in addition to their own R&D capabilities. The DOE labs bring broad R&D capabilities and perspectives from other areas of research application. The strong synergy between industry and DOE will enable this collaboration to significantly impact industry competitiveness while focusing and strengthening, the labs` capabilities consistent with DOE`s mission. There are three main components in AMTEX: DOE/ER oversight; the Operating Committee, which is composed a Laboratory Board and an Industry Board; and five Technology Area Coordination Teams (TACTs).

  8. The AMTEX Partnership

    Energy Technology Data Exchange (ETDEWEB)

    Lemon, D.K.


    The American Textile Partnership, as its name implies, is a collaborative effort between the DOE national labs and industry-related R D/educational institutions. The purpose of AMTEX is to promote R D that enhance the competitiveness of the integrated textile industry (i.e., fibers, textiles, sewn/fabricated products). The industry-related organizations bring a vital perspective of industry needs in addition to their own R D capabilities. The DOE labs bring broad R D capabilities and perspectives from other areas of research application. The strong synergy between industry and DOE will enable this collaboration to significantly impact industry competitiveness while focusing and strengthening, the labs' capabilities consistent with DOE's mission. There are three main components in AMTEX: DOE/ER oversight; the Operating Committee, which is composed a Laboratory Board and an Industry Board; and five Technology Area Coordination Teams (TACTs).

  9. Public-Private Partnerships

    DEFF Research Database (Denmark)

    Helby Petersen, Ole

    This PhD dissertation studies national similarities and differences in policy and regulation of public-private partnerships (PPPs), with an empirical focus on Denmark and Ireland. The starting point and motivation for the study is the observation that whereas PPPs are often depicted in the academic...... time, and how can their similarities and differences be explained?; (iii) how do differing national policy and regulation frameworks serve to facilitate or hinder the formation of PPPs, exemplified by four case studies from the schools sector?; (iv) what framework conditions does the EU set for PPP...... literature and in policy practice as a globally disseminated governance scheme, in reality, a closer examination of the PPP reform landscape reveals significant differences in national governments’ PPP policy and regulation and in the amount of actually implemented PPP projects. By comparing the initiatives...

  10. The GLOBE Program: Partnerships in Action (United States)

    Henderson, S.; Kennedy, T.; Lemone, M.; Blurton, C.


    The GLOBE Program is a worldwide science and education partnership endeavor designed to increase scientific understanding of Earth as a system, support improved student achievement in science and math, and enhance environmental awareness through inquiry-based learning activities. GLOBE began on the premise that teachers and their students would partner with scientists to collect and analyze environmental data using specific protocols in five study areas - atmosphere, soils, hydrology, land cover, and phenology. As the GLOBE network grew, additional partnerships flourished making GLOBE an unprecedented collaboration of individuals worldwide - primary, secondary, and tertiary students, teachers and teacher educators, scientists, government officials, and others - to improve K-12 education. Since its inception in 1994, more than one million students in over 14,000 schools around the world have taken part in The GLOBE Program. The GLOBE Web site ( is the repository for over 11 million student-collected data measurements easily accessible to students and scientists worldwide. Utilizing the advantages of the Internet for information sharing and communication, GLOBE has created an international community. GLOBE enriches students by giving them the knowledge and skills that they will need to become informed citizens and responsible decision-makers in an increasingly complex world. Understanding that all members of a community must support change if it is to be sustainable, GLOBE actively encourages the development of GLOBE Learning Communities (GLCs) which are designed to get diverse stakeholder groups involved in a local or regional environmental issue. Central to the GLC is the engagement of local schools. GLCs go beyond individual teachers implementing GLOBE in the isolation of their classrooms. Instead, the GLC brings multiple teachers and grade levels together to examine environmental issues encouraging the participation of a broad range of

  11. Forging School-Scientist Partnerships: A Case of Easier Said than Done? (United States)

    Falloon, Garry


    Since the early 1980s, a number of initiatives have been undertaken worldwide which have involved scientists and teachers working together in projects designed to support the science learning of students. Many of these have attempted to establish school-scientist partnerships. In these, scientists, teachers, and students formed teams engaged in mutually beneficial science-based activities founded on principles such as equal recognition and input, and shared vision, responsibility and risk. This article uses two partnership programmes run by a New Zealand Science Research Institute, to illustrate the challenges faced by scientists and teachers as they attempted to forge meaningful and effective partnerships. It argues that achieving the theorised position of a shared partnership space at the intersection of the worlds of scientists and teachers is problematic, and that scientists must instead be prepared to penetrate deeply into the world of the classroom when undertaking any such interactions. Findings indicate epistemological differences, curriculum and school systems and issues, and teacher efficacy and science knowledge significantly affect the process of partnership formation. Furthermore, it is argued that a re-thinking of partnerships is needed to reflect present economic and education environments, which are very different to those in which they were originally conceived nearly 30 years ago. It suggests that technology has an important role to play in future partnership interactions.

  12. Growing partnerships: leveraging the power of collaboration through the Medical Education Partnership Initiative. (United States)

    Olapade-Olaopa, Emiola Oluwabunmi; Baird, Sarah; Kiguli-Malwadde, Elsie; Kolars, Joseph C


    A major goal of the Medical Education Partnership Initiative (MEPI) is to improve local health systems by strengthening medical education in Sub-Saharan Africa. A new approach to collaboration was intended to overcome the one-sided nature of many partnerships that often provide more rewards to institutions from wealthy countries than to their Sub-Saharan African counterparts. The benefits of this MEPI approach are reflected in at least five positive outcomes. First, effective partnerships have been developed across a diverse group of MEPI stakeholders. Second, a "community of practice" has been established to continue strengthening medical education in Sub-Saharan Africa. Third, links have been strengthened among MEPI health science schools in Sub-Saharan Africa, their communities, and ministries of both health and education. Fourth, respect among partners in the United States for a culture of ownership and self-determinism among their African counterparts committed to improving education has been enhanced. And finally, performance metrics for strengthening of health science education in Sub-Saharan Africa have been advanced. Meanwhile, partner medical schools in the United States have witnessed the benefits of collaborating across traditional disciplinary boundaries, such as physicians working within highly functioning community-based health care teams with many of the participating schools in Sub-Saharan Africa. MEPI demonstrates that North-South as well as South-South partnerships, with an explicit focus on improving local health systems through better education, can be designed to empower partners in the South with support from collaborators in the North.

  13. Species of conservation concern and environmental stressors: local regional and global effects: Chapter 6 in The Southern Nevada Agency Partnership science and research synthesis: science to support land management in southern Nevada (United States)

    Ostoja, Steven M.; Brooks, Matthew L.; Chambers, Jeanne C.; Pendleton, Burton


    Science Research Strategy which is to sustain and enhance southern Nevada's biotic communities to preserve biodiversity wand maintain viable populations (table 1.3; Turner and others 2009). We provide numerous examples of how stressors affect the range and/or habitat of select species of conservation concern. It is important to note that the species or groups discussed in this chapter by no means represent a comprehensive treatment of all species of conservation concern listed in Table 1.2 (Chapter 1). Rather, several species were chosen as examples for each southern Nevada ecosystem type to illustrate how stressors and linkages among them can affect species of conservation concern, keeping in mind that many of the species considered here are found in more than one ecosystem type. In addition, the stressors that may impact a species in one ecosystem may not be those that affect it in another ecosystem and different species in the same ecosystem may not be affected by the same suite of stressors. Finally, at the start of each ecosystem section we summarize key resource concerns, species used as examples, key stressors, and potential synergistic effects of those stressors relative to the species example.

  14. Southwest Regional Partnership on Carbon Sequestration

    Energy Technology Data Exchange (ETDEWEB)

    Brian McPherson


    The Southwest Partnership on Carbon Sequestration completed its Phase I program in December 2005. The main objective of the Southwest Partnership Phase I project was to evaluate and demonstrate the means for achieving an 18% reduction in carbon intensity by 2012. Many other goals were accomplished on the way to this objective, including (1) analysis of CO{sub 2} storage options in the region, including characterization of storage capacities and transportation options, (2) analysis and summary of CO{sub 2} sources, (3) analysis and summary of CO{sub 2} separation and capture technologies employed in the region, (4) evaluation and ranking of the most appropriate sequestration technologies for capture and storage of CO{sub 2} in the Southwest Region, (5) dissemination of existing regulatory/permitting requirements, and (6) assessing and initiating public knowledge and acceptance of possible sequestration approaches. Results of the Southwest Partnership's Phase I evaluation suggested that the most convenient and practical ''first opportunities'' for sequestration would lie along existing CO{sub 2} pipelines in the region. Action plans for six Phase II validation tests in the region were developed, with a portfolio that includes four geologic pilot tests distributed among Utah, New Mexico, and Texas. The Partnership will also conduct a regional terrestrial sequestration pilot program focusing on improved terrestrial MMV methods and reporting approaches specific for the Southwest region. The sixth and final validation test consists of a local-scale terrestrial pilot involving restoration of riparian lands for sequestration purposes. The validation test will use desalinated waters produced from one of the geologic pilot tests. The Southwest Regional Partnership comprises a large, diverse group of expert organizations and individuals specializing in carbon sequestration science and engineering, as well as public policy and outreach. These partners

  15. 46 CFR 67.35 - Partnership. (United States)


    ... 46 Shipping 2 2010-10-01 2010-10-01 false Partnership. 67.35 Section 67.35 Shipping COAST GUARD... Citizenship Requirements for Vessel Documentation § 67.35 Partnership. A partnership meets citizenship... recreational endorsement, at least 50 percent of the equity interest in the partnership is owned by citizens...

  16. University Data Partnership Peer Exchange (United States)


    In March 2012, the Connecticut (CTDOT) and New Mexico (NMDOT) Departments of Transportation met in Baton Rouge, Louisiana for a two-day peer session dedicated to exploring the intricate 12-year safety data partnership between the Louisiana Department...

  17. NREL: International Activities - Bilateral Partnerships (United States)

    resource assessment, integration of diverse energy sources, systems modeling, and business models for In partnership with the Organization of American States and other multinational organizations, NREL , Industry and Tourism; Finance and Public Credit; and Agriculture. Europe NREL collaborates with many

  18. F-Gas Partnership Programs (United States)

    Provides basic information and resources for the Fluorinated Gas Partnership Programs, which were launched as a joint effort by EPA and industry groups to reduce the amount of fluorinated gases emitted through a variety of industrial processes.

  19. Networking the Global Maritime Partnership

    National Research Council Canada - National Science Library

    Galdorisi, George; Hszieh, Stephanie; McKearney, Terry


    The modern-day notion of a "Global Maritime Partnership," first introduced by then-CNO Admiral Michael Mullen at the 2005 International Seapower Symposium as "The 1000-Ship Navy," and later enshrined in the new U.S...

  20. Using social media to promote international student partnerships. (United States)

    Garrett, Bernard M; Cutting, Roger


    This paper describes a project to establish and evaluate online study partnerships, using social networking applications, between final year Canadian nursing students at the University of British Columbia (UBC) and second year undergraduate science education students at the University of Plymouth (UoP) in the UK. The project took place between 2009 and 2010 and evaluated the use of social networking applications with international interdisciplinary partnerships between Canadian and UK students. A multi-method evaluation strategy incorporating questionnaires, online focus groups and web analytics was used to explore the value of social media to promote the exchange of ideas and discussion of scientific philosophy in different contexts, between students working in disciplines with differing philosophical perspectives principally modern/post-modern, quantitative/qualitative, empirical/theoretical. This project resulted in a very successful collaborative partnership between UK and Canadian students. Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. Musselwhite partnership produces results

    Energy Technology Data Exchange (ETDEWEB)

    Larmour, A.


    Hydro One will install transmission lines between Nipigon and Pickle Lake as one of 20 projects in Ontario's ambitious $2.3 billion green-energy makeover. The electrical power grid will be extended to the region at the request of a group of northwestern Ontario First Nation communities and representatives from Goldcorp Inc.'s Musselwhite Mine, who wanted a reliable source of energy in this remote area. The partnership between Goldcorp and the First Nation communities began in the late 1980s. The Musselwhite Agreement was one of the first Impact Benefit Agreements negotiated in Ontario. Initially signed in 1996, the 5-year deal was renewed in 2001 and 2006. One of the communities at North Caribou Lake has a population of 780 and is located approximately 320 kilometres north of Sioux Lookout. It is one of 4 First Nation communities and 2 tribal councils that have negotiated the sharing of resources from the Musselwhite gold mine, originally owned and operated by Placer Dome. This article discussed some of the best practices in building relationships with community leaders and members. Industry needs to understand the governance of a First Nation community and how they are set up in their decision-making process. Other negotiated aspects within the agreement are revenue sharing and employment. A target of 30 per cent First Nation employment was set for the signatory and affiliate communities. 2 refs., 1 fig.

  2. Sustainable partnerships; Parcerias sustentaveis

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Ana Claudia L.C.; Medau, Michelle; Nascimento, Patricia M.; Ruiz, Rogerio H. [Companhia de Gas de Sao Paulo (COMGAS), Sao Paulo, SP (Brazil)


    This paper describes the experience of the Gas Company of Sao Paulo - COMGAS in regard to the plantations of seedlings of native tree species as a compensatory measure in licensing regarding intervention in the Preservation Area Standing. The work for the installation of gas pipeline are subject to environmental licensing, and within the context of this specific permit, any intervention in the Preservation Area Standing - APP, or any opening of mass grave or not that results in removal of native vegetation or exotic, generates a Statement of Commitment to Environmental Recovery - TCRA issued by the State Department of Protection of Natural Resources - DEPRN, organ of SMA that licenses the operations on vegetation and wildlife in the State, compensation for the use of Natural Resource (APP). These terms are the reforestation of areas devoid of vegetation, carrying tree or enrichment of fragments without ecological sustainability. To that their plantations were able to pose a greater environmental significance, COMGAS started processes of partnerships that has so far planted about 58,000 seedlings of native species. (author)

  3. Supporting sound partnerships

    International Nuclear Information System (INIS)

    McManus, B.


    According to the Alberta Energy Resources Conservation Board's (ERCB) business plan, the ERCB needs to continue its priority of assessing the interests of government, industry, the public and other stakeholders and be responsive to their needs. This presentation discussed the evolution of noise criteria requirements and the establishment of a regulatory foundation with ERCB Directive 038, which is the only comprehensive noise requirement in the province and works towards building relationships with industry and the community to address noise issues. The role of the field centres was also outlined. Their role is to respond and investigate noise complaints throughout the province; communicate with landowners and industry on the front lines; and identify compliance of facilities. Alternative dispute resolution and noise issues were discussed. The field centres facilitate communication between landowners and industry and resolution of noise issues through a collaborative process. The presentation also outlined the role of community and Aboriginal involvement; the role of synergy groups; and successes such as the Sundre Petroleum Operators Group and Aberdeen Pilot Project. It was concluded that Directive 038 promotes noise awareness and strong partnerships with stakeholders.

  4. Job loss and broken partnerships

    DEFF Research Database (Denmark)

    Kriegbaum, Margit; Christensen, Ulla; Lund, Rikke


    The aim of this study was to investigate the effects of the accumulated number of job losses and broken partnerships (defined as the end of cohabitation) on the risk of fatal and nonfatal events of ischemic heart disease (IHD).......The aim of this study was to investigate the effects of the accumulated number of job losses and broken partnerships (defined as the end of cohabitation) on the risk of fatal and nonfatal events of ischemic heart disease (IHD)....

  5. Untangling Partnership and Domination Morality

    Directory of Open Access Journals (Sweden)

    David Loye


    Full Text Available Riane Eisler’s (1987 cultural transformation theory is an effective framework for understanding many of the constructs that shape society. This article uses Eisler’s theory to explain the formation of morality and the construction of conscience. It contrasts partnership morality and domination morality, and describes the factors that shape our tendency to embrace one or the other. The article helps us understand that we have a choice, and invites us to choose partnership morality.

  6. science

    International Development Research Centre (IDRC) Digital Library (Canada)

    David Spurgeon

    Give us the tools: science and technology for development. Ottawa, ...... altered technical rela- tionships among the factors used in the process of production, and the en- .... to ourselves only the rights of audit and periodic substantive review." If a ...... and destroying scarce water reserves, recreational areas and a generally.

  7. A study of a museum-school partnership (United States)

    Wojton, Mary Ann

    Partnerships between museums and schools never have been more important than they are today. Schools, especially urban schools, are facing challenges, including low student achievement and difficulty obtaining funding. Partners can help schools overcome these challenges by sharing educational and financial resources. Nearly 11,000 American museums spend more than $1 billion annually to provide over 18 million instructional hours for k-12 educational programs such as professional development for teachers, guided field trips, and staff visits to schools. Museums would seem like natural partners for challenged urban schools. Yet museums and schools struggle to establish and maintain effective partnerships. This study examined a partnership between a science center and an urban elementary school to provide additional knowledge and resources for those in the field to overcome these challenges in order to create relationships that help students. Using qualitative methods with interpretive descriptive purposes (Erickson, 1986; Glesne, 1999; Lincoln & Guba, 2000), the research design is based on several methods of data collection, including face-to-face, semi-structured interviews; observations; written text; and field notes. Participants in this study included students, parents, teachers, school administrators and museum educators. In addition, adult representatives of community organizations were interviewed to determine the impact of the partnership on the community. The study found that an effective partnership will have four basic elements: mutual goals, communication plan, key leader support, planning and research, and four interpersonal elements: personal responsibility, honesty, communication at the intimate level, and trust. Partners may have difficulty developing these to their fullest extent due to time limitations. No partnership is perfect. By creating strong interpersonal relationships, partners can mitigate challenges caused by limited basic elements and





    The partnership is now increasingly used in all areas thanks to the synergy it implies and of the benefits demonstrated. And in today's economy benefits of the partnership are widely recognized. Partnership in purchase makes no exception. This paper presents the benefits of a partnership-based purchases compared to those of traditional purchasing. Less well known is that a partnership built and/or implemented incorrectly and may result in additional costs and thus lead to disadvantages for...

  9. Phase 1 trial of the Plasmodium falciparum blood stage vaccine MSP1(42-C1/Alhydrogel with and without CPG 7909 in malaria naïve adults.

    Directory of Open Access Journals (Sweden)

    Ruth D Ellis


    Full Text Available Merozoite surface protein 1(42 (MSP1(42 is a leading blood stage malaria vaccine candidate. In order to induce immune responses that cover the major antigenic polymorphisms, FVO and 3D7 recombinant proteins of MSP1(42 were mixed (MSP1(42-C1. To improve the level of antibody response, MSP1(42-C1 was formulated with Alhydrogel plus the novel adjuvant CPG 7909.A Phase 1 clinical trial was conducted in healthy malaria-naïve adults at the Center for Immunization Research in Washington, D.C., to evaluate the safety and immunogenicity of MSP1(42-C1/Alhydrogel +/- CPG 7909. Sixty volunteers were enrolled in dose escalating cohorts and randomized to receive three vaccinations of either 40 or 160 microg protein adsorbed to Alhydrogel +/- 560 microg CPG 7909 at 0, 1 and 2 months.Vaccinations were well tolerated, with only one related adverse event graded as severe (Grade 3 injection site erythema and all other vaccine related adverse events graded as either mild or moderate. Local adverse events were more frequent and severe in the groups receiving CPG. The addition of CPG enhanced anti-MSP1(42 antibody responses following vaccination by up to 49-fold two weeks after second immunization and 8-fold two weeks after the third immunization when compared to MSP1(42-C1/Alhydrogel alone (p<0.0001. After the third immunization, functionality of the antibody was tested by an in vitro growth inhibition assay. Inhibition was a function of antibody titer, with an average of 3% (range -2 to 10% in the non CPG groups versus 14% (3 to 32% in the CPG groups.The favorable safety profile and high antibody responses induced with MSP1(42-C1/Alhydrogel + CPG 7909 are encouraging. MSP1(42-C1/Alhydrogel is being combined with other blood stage antigens and will be taken forward in a formulation adjuvanted with CPG Identifier: NCT00320658.

  10. Education in the Direction of Public-Private Partnership

    Directory of Open Access Journals (Sweden)

    Norma Suely Siqueira Eiras


    Full Text Available The process of the neoliberalism reveals, at its more intense moment, the submission of all the levels of the life human being the mercantile transactions, the capitalist inclination to the world-wide trading. In this manner, the neoliberal proposals objectify, over all, the creation of an only feeling to guarantee the success of its ideals of globalization, free-economy and State minimum, not inhibit the social politics, but partnership of the market. Amongst the artifices used for the neoliberal proposers, placed the Public-Private Partnerships (PPPs with which this article concerns. From the conceptualization and characterization of the instrument Public-Private Partnerships (PPPs, national and European projects, developed through the PPPs, had been analyzed. The subjects of these projects involve Technology of Computer science and Communication and eLearning (education + technology + in the distance. Reflections had evidenced that the partnerships between governments and multinationals companies can lead to a loss of control on the part of the State on the educational formation of the citizens and the loss of identity of its resumes. The explanation for this phenomenon happens of the trend to the globalization. On the other hand, these partnerships bring profits politicians to the governments and economic to the companies.

  11. The Independence of Notary in The Civil Partnership of Notary

    Directory of Open Access Journals (Sweden)

    Adha Dia Agustin


    Full Text Available The continued development of business in Indonesia, would make the greater role of the notary. The number of notaries and needed in each region in Indonesia gets greater. This rapid development, then coupled with the new policy. Previously, Peraturan Jabatan Notaris(PJN prohibited Perserikatan, but since the establishment of Undang-Undang Jabatan Notaris (UUJN has changed otherwise. Notary possible to make associations in a Civil Partnership. Even Peraturan Menteri Hukum dan HAM RI Nomor: M.HH.01.AH.02.12 Tahun 2010 tentang Persyaratan Menjalankan Jabatan Notaris Dalam Bentuk Perserikatan Perdata described the formation of the implementing regulations of the Civil Partnership. Is it true that Civil Partnership would make science benefit for junior notary and will facilitate the work of a Notary Or it would make large colonies notary who compete each other, so that the function of a notary public is no longer as state officials, but it called the company deed. This journal examines the Civil Partnership in Kitab Undang-Undang Hukum Perdata and would review the principle of the independence of the notary as set forth in Undang-Undang Jabatan Notaris. How To Cite: Agustin, A. (2014. The Independence of Notary in The Civil Partnership of Notary. Rechtsidee, 1(2, 131-146. doi:

  12. MspI and PvuII polymorphisms in the Na,K-ATPase. alpha. subunit related gene ATP1AL1

    Energy Technology Data Exchange (ETDEWEB)

    Shull, M.M.; Pugh, D.G.; Lingrel, J.B. (Univ. of Cincinnati, OH (USA))


    ATP1AL1 78-1-3 is a 0.56 kb genomic EcoRI-XbaI fragment from within the Na,K-ATPase {alpha} subunit related gene, previously referred to as {alpha}D on chromosome 13. The fragment was subcloned into pIBI31. MspI identifies a two-allele polymorphism (M1: 2.8 kb, M2: 2.5 kb). PvuII, which cuts within the probe sequence, detects two two-allele polymorphism (A1: 6.0 kb, A2: 5.7 kb, B1: 1.3 kb, B2: 1.1 kb). A1 and A2 appear to result from an insertion/deletion polymorphism that is also identified by MspI. ATP1AL1 78-1-3 has been assigned to chromosome 13q by somatic cell hybrid analysis. Codominant segregation of the RELPs was observed in 2 two-generation families.

  13. Scientists + Artists: An Introduction to Mutually Beneficial Partnerships (United States)

    Sparks, A.


    As world leaders, climate and energy scientists, and others examine our future climate, new ways of collaborating and communicating across different social sectors are becoming more crucial. What images and stories are evoked when you think about the future of the planet? Storytelling and images are basic tools for artists, and are increasingly recognized as critical tools for scientists, educators, and people interested in communicating science to broader public audiences. Science/arts collaborations have numerous benefits and can be challenging when partners have different lexicons for making sense of the world. This participatory session will explore the benefits and role of science/arts partnerships when communicating and engaging with stakeholders from varying backgrounds. Attendees will develop shared vocabulary and examine collaborative tools that can help both non-artists and non-scientists better communicate about climate change, energy policies, and other topics. For newcomers, this will be a 101 primer to community engagement and using the arts and/or collaborating with artists to reach broader audiences with your work. Experienced attendees will examine their own previous partnerships to reflect on the successes and learn from the challenges. Topics to be covered include: 1) understanding shared values between artists/scientists; 2) clarifying target audiences; and 3) identifying factors and components critical for healthy partnerships across sectors. Theater director and engagement strategist Ashley Sparks leads this interactive session and reflects on learnings from her partnership with the Energy Foundation, the Network for Energy, Water, and Health in Affordable Buildings, and the Natural Resources Defense Council. In partnership with engineers and technical experts she has been leading efforts to create a story bank focused on increasing energy efficiency in affordable multifamily housing.

  14. Global partnerships: Expanding the frontiers of space exploration education (United States)

    MacLeish, Marlene Y.; Akinyede, Joseph O.; Goswami, Nandu; Thomson, William A.


    Globalization is creating an interdependent space-faring world and new opportunities for international partnerships that strengthen space knowledge development and transfer. These opportunities have been codified in the Global Exploration Strategy, which endorses the "inspirational and educational value of space exploration" [1]. Also, during the 2010 Heads of Space Agencies Summit celebrating the International Academy of Astronautics' (IAA) 50th Anniversary, space-faring nations from across the globe issued a collective call in support of robust international partnerships to expand the frontiers of space exploration and generate knowledge for improving life on Earth [2]. Educators play a unique role in this mission, developing strategic partnerships and sharing best educational practices to (1) further global understanding of the benefits of space exploration for life on Earth and (2) prepare the next generation of scientists required for the 21st Century space workforce. Educational Outreach (EO) programs use evidence-based, measurable outcomes strategies and cutting edge information technologies to transfer space-based science, technology, engineering and mathematics (STEM) knowledge to new audiences; create indigenous materials with cultural resonance for emerging space societies; support teacher professional development; and contribute to workforce development initiatives that inspire and prepare new cohorts of students for space exploration careers. The National Space Biomedical Research Institute (NSBRI), the National Aeronautics and Space Administration (NASA) and Morehouse School of Medicine (MSM) have sustained a 13-year space science education partnership dedicated to these objectives. This paper briefly describes the design and achievements of NSBRI's educational programs, with special emphasis on those initiatives' involvement with IAA and the International Astronautical Congress (IAC). The IAA Commission 2 Draft Report, Space for Africa, is discussed

  15. How We Forged an Alliance for Science. (United States)

    Cravotta, Lee J.


    A seven-year-old partnership between a school district and a Fortune 500 company has provided financial assistance to the district, expanded student interest in science, and encouraged teacher development in science. (MLF)

  16. Associação entre os polimorfismos HaeIII e MspI do gene para o receptor alfa de estrogênio e densidade mamográfica em mulheres após a menopausa Association between HaeIII and MspI polymorphisms of estrogen receptor alpha gene and mammographic density in post-menopausal women

    Directory of Open Access Journals (Sweden)

    Eduardo Henrique de Moura Ramos


    Full Text Available OBJETIVO: Avaliar a presença dos polimorfismos HaeIII e MspI do gene para o receptor de estrogênio alfa, bem como fatores clínicos e suas possíveis associações com a densidade mamográfica em mulheres após a menopausa. MÉTODOS: Foram avaliadas 115 mulheres após a menopausa, não usuárias de terapia hormonal e sem lesão mamária clínica ou mamograficamente identificada. A densidade mamográfica foi determinada por três observadores independentes, tomando-se como base a classificação dos padrões mamográficos do ACR-BIRADS®, 2003 (duas avaliações subjetivas e uma computadorizada - Adobe Photoshop® 7.0. Amostras de raspado bucal foram obtidas para extração de DNA e em seguida foi realizada uma PCR-RFLP (Polymerase Chain Reation - Restriction Fragment Length Polymorphism para análise de polimorfismos presentes no íntron 1 e éxon 1 do gene do REalfa (HaeIII e MspI. RESULTADOS: O polimorfismo HaeIII foi encontrado em 43 (37,4% das 115 mulheres, ao passo que o MspI estava presente em 96 (83,5% das mesmas. Houve alto grau de concordância entre os três observadores na determinação da densidade mamográfica. Trinta e quatro (29,6% mulheres tinham mamas densas, e 81 (70,4%, mamas lipossubstituídas. CONCLUSÃO: Não houve associação entre o polimorfismo HaeIII do gene para o receptor de estrogênio alfa e densidade mamográfica (Fisher = 0,712. Houve associação próxima à significância estatística entre o polimorfismo MspI e densidade (Fisher = 0,098. Idade, paridade e índice de massa corporal mostraram-se associados com densidade mamográfica.PURPOSE: To assess the presence of estrogen receptor gene polymorphisms HaeIII and MspI as well as clinical factors, and their possible associations with high mammographic density in post-menopausal women. METHODS: One hundred and fifteen post-menopausal women, not in use of hormonal therapy and without clinical or mammographic lesions were evaluated. Three independent observers

  17. Covariates of Multiple Sexual Partnerships among Sexually Active ...

    African Journals Online (AJOL)


    The aim of this paper is to identify the social and economic variables associated with MSP among ... rate of AIDS pandemic in sub-Saharan Africa, ... which address the spread of HIV through ... sexual networks observed in the southern African.

  18. NATO's Strategic Partnership with Ukraine

    DEFF Research Database (Denmark)

    Breitenbauch, Henrik Ø.


    Russian actions in Ukraine have altered the security land- scape in Europe, highlighting a renewed emphasis on the differences between members and non-members. In this context, NATO must a) create a strategic understanding of partnerships as something that can be transformative, even if it will n......Russian actions in Ukraine have altered the security land- scape in Europe, highlighting a renewed emphasis on the differences between members and non-members. In this context, NATO must a) create a strategic understanding of partnerships as something that can be transformative, even...... if it will not lead to membership in the short or even long term, and b) build such a strategic relationship with Ukraine. In sum, the Russian-induced Ukraine crisis should spur the reform of NATO partnerships – with Ukraine as a case in point....

  19. Analysis of RET promoter CpG island methylation using methylation-specific PCR (MSP), pyrosequencing, and methylation-sensitive high-resolution melting (MS-HRM): impact on stage II colon cancer patient outcome. (United States)

    Draht, Muriel X G; Smits, Kim M; Jooste, Valérie; Tournier, Benjamin; Vervoort, Martijn; Ramaekers, Chantal; Chapusot, Caroline; Weijenberg, Matty P; van Engeland, Manon; Melotte, Veerle


    Already since the 1990s, promoter CpG island methylation markers have been considered promising diagnostic, prognostic, and predictive cancer biomarkers. However, so far, only a limited number of DNA methylation markers have been introduced into clinical practice. One reason why the vast majority of methylation markers do not translate into clinical applications is lack of independent validation of methylation markers, often caused by differences in methylation analysis techniques. We recently described RET promoter CpG island methylation as a potential prognostic marker in stage II colorectal cancer (CRC) patients of two independent series. In the current study, we analyzed the RET promoter CpG island methylation of 241 stage II colon cancer patients by direct methylation-specific PCR (MSP), nested-MSP, pyrosequencing, and methylation-sensitive high-resolution melting (MS-HRM). All primers were designed as close as possible to the same genomic region. In order to investigate the effect of different DNA methylation assays on patient outcome, we assessed the clinical sensitivity and specificity as well as the association of RET methylation with overall survival for three and five years of follow-up. Using direct-MSP and nested-MSP, 12.0 % (25/209) and 29.6 % (71/240) of the patients showed RET promoter CpG island methylation. Methylation frequencies detected by pyrosequencing were related to the threshold for positivity that defined RET methylation. Methylation frequencies obtained by pyrosequencing (threshold for positivity at 20 %) and MS-HRM were 13.3 % (32/240) and 13.8 % (33/239), respectively. The pyrosequencing threshold for positivity of 20 % showed the best correlation with MS-HRM and direct-MSP results. Nested-MSP detected RET promoter CpG island methylation in deceased patients with a higher sensitivity (33.1 %) compared to direct-MSP (10.7 %), pyrosequencing (14.4 %), and MS-HRM (15.4 %). While RET methylation frequencies detected by nested-MSP

  20. Quality assessment of DNA derived from up to 30 years old formalin fixed paraffin embedded (FFPE) tissue for PCR-based methylation analysis using SMART-MSP and MS-HRM. (United States)

    Kristensen, Lasse S; Wojdacz, Tomasz K; Thestrup, Britta B; Wiuf, Carsten; Hager, Henrik; Hansen, Lise Lotte


    The High Resolution Melting (HRM) technology has recently been introduced as a rapid and robust analysis tool for the detection of DNA methylation. The methylation status of multiple tumor suppressor genes may serve as biomarkers for early cancer diagnostics, for prediction of prognosis and for prediction of response to treatment. Therefore, it is important that methodologies for detection of DNA methylation continue to evolve. Sensitive Melting Analysis after Real Time - Methylation Specific PCR (SMART-MSP) and Methylation Sensitive - High Resolution Melting (MS-HRM) are two methods for single locus DNA methylation detection based on HRM. Here, we have assessed the quality of DNA extracted from up to 30 years old Formalin Fixed Paraffin Embedded (FFPE) tissue for DNA methylation analysis using SMART-MSP and MS-HRM. The quality assessment was performed on DNA extracted from 54 Non-Small Cell Lung Cancer (NSCLC) samples derived from FFPE tissue, collected over 30 years and grouped into five years intervals. For each sample, the methylation levels of the CDKN2A (p16) and RARB promoters were estimated using SMART-MSP and MS-HRM assays designed to assess the methylation status of the same CpG positions. This allowed for a direct comparison of the methylation levels estimated by the two methods for each sample. CDKN2A promoter methylation levels were successfully determined by SMART-MSP and MS-HRM in all 54 samples. Identical methylation estimates were obtained by the two methods in 46 of the samples. The methylation levels of the RARB promoter were successfully determined by SMART-MSP in all samples. When using MS-HRM to assess RARB methylation five samples failed to amplify and 15 samples showed a melting profile characteristic for heterogeneous methylation. Twenty-seven of the remaining 34 samples, for which the methylation level could be estimated, gave the same result as observed when using SMART-MSP. MS-HRM and SMART-MSP can be successfully used for single locus

  1. The Logic of Public-Private Partnerships

    DEFF Research Database (Denmark)

    Greve, Carsten; Hodge, Graeme

    This paper is situated at the nexus of two literatures: theoretical ideas from political science on the relationship between politics and markets, and the more recent public policy phenomenon of public-private partnerships (PPPs). It aims firstly to map some of the primary theoretical underpinnings...... describing the enduring relationship between governments and businesses. It then focuses on the adoption of PPPs as a popular infrastructure policy, and asks to what extent a particular political-market logic for the adoption of PPP policies appears to exist in leading jurisdictions such as the UK, Australia...... and Canada. It suggests that the empirical evidence on the undue influence of business over political decision making is not one sided and that the arena is still hotly contested. It also suggests that the policy logic of PPPs may be dependent on the relative maturity of governance systems, the relative...

  2. Adding SPICE to Science (United States)

    Levey, Douglas


    In this article, the author would like to raise awareness of GK?12 programs by sharing experiences from SPICE (Science Partners in Inquiry-based Collaborative Education), a partnership between the University of Florida and Alachua County Public Schools. SPICE pairs nine graduate student fellows with nine middle school science teachers. Each…

  3. Partnership Education in the Forest

    Directory of Open Access Journals (Sweden)

    Heidi G Bruce


    Full Text Available Heidi Bruce is a founding board member of the Orcas Island Forest School, an outdoor early childhood education program located on Orcas Island, Washington State. In this article, she describes the interconnectedness of nature-based education and Partnership education, as outlined in Riane Eisler‘s book, Tomorrow’s Children: A Blueprint for Partnership Education in the 21st Century (2000. She also shares her experience in advocating for the first legislation in the country that creates a pilot program for licensing nature-based early childhood education programs.

  4. The Dilemma of Professional Partnerships

    DEFF Research Database (Denmark)

    Bévort, Frans; Poulfelt, Flemming

    A large and growing proportion of the organizations in the contemporary knowledge economy are organized as professional partnerships as is the case of professional service firms. As these firms have grown larger (e.g. Big4: Deloitte, PwC, E&Y, KPMG), the way of organizing is under pressure...... other sources, the paper analyzes the changing organization of work, the changing partner and manager roles and basic changes in the HR-model. The paper explores the question of where the partnership organization is going and discusses potentials and pitfalls for this particular type of organization....

  5. Canada's family violence initiative: partnerships

    Directory of Open Access Journals (Sweden)

    Elaine Scott


    Full Text Available Under Canada's four-year, $136 million Family Violence Initiative, the federal government is calling upon all Canadians to work in partnerships towards the elimination of family violence - child abuse, violence against women, and elder (senior abuse. Family violence is a complex problem and requires the efforts of all Canadians to resolve it. One of the key themes of the Initiative - a multidisciplinary approach to the problem of family violence - is reflected in the selection and development of projects. Activities funded by the seven federal departments and agencies involved in the Initiative emphasize partnerships with the professional, voluntary, corporate, non-government and government sectors.

  6. Pathological buying and partnership status. (United States)

    Müller, Astrid; de Zwaan, Martina; Mitchell, James E; Zimmermann, Tanja


    This pilot study investigated the partnership status and the level of pathological buying (PB) in 157 female patients with PB and 1153 women from a German population-based sample. Slightly more than half of both samples were currently living with a partner. The results suggest a protective effect of being in a couple relationship in the representative sample. In contrast, having a partner was not related to the severity of PB among patients. Future studies should address the question of whether the characteristics and quality of partnership have an impact on the severity and course of PB, and vice versa. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  7. Transferring nuclear knowledge - An international partnership

    International Nuclear Information System (INIS)

    Badawy, I.I.


    Full text: The fast decrease of coal, oil and natural gas as energy resources is pushing the world towards the use of nuclear energy. The expectation of growth in the nuclear field seems to be a great challenge -specially- in developing countries which are in hard need of acquiring nuclear knowledge and nuclear technology as well. In this situation, various factors would have great influence on the implementation of nuclear projects -in particular- for electricity generation. As a matter of fact, it is essential for each country to have its own strategy for national development. In practice, the implementation of such a strategy would need the collective efforts of specialized and efficient human resources for executing the tasks. This would need cooperation with, and/or technical aid of developed countries and international organizations. There are various parameters that may contribute in the national development in a country, the most important of which are the development in science and technology. Then, the industrial development becomes essential for the nuclear industry. In order to achieve this, the information acquiring and knowledge transfer are fundamental tools. The partnership between developed and developing countries would mean cooperation and aid directed to nuclear technology and knowledge transfer; and specialized technical training in the nuclear industry. Supplier countries might need to use high technology in implementing nuclear safeguards commitments, but with minimum side effects. This paper investigates some factors that may have influence on transferring peaceful uses of nuclear knowledge and/or nuclear technology; such as establishing and sustaining the national nuclear workforce, building of public understanding and public acceptance of nuclear science and technology. Also, it discusses the importance of activating and strengthening the international regime of partnership for the welfare and prosperity of human kind; with specific

  8. Feast of Science Sense-Ations (United States)

    Lewis, Elaine; Bullimore, Hayley; Krupa, Amy; Gaschk, Katherine; Pearson, Jennifer


    Science expositions at the Canning River Eco Education Centre (CREEC), Perth, Western Australia, have been conducted over the last five years (2009-2013) during National Science Week. These expos aimed to enhance science understanding in the community, foster partnerships for science and promote science careers by providing a scientific feast for…

  9. BEGIN Partnership: Using Problem-Based Learning to Teach Genetics & Bioethics (United States)

    Markowitz, Dina; DuPre, Michael J.; Holt, Susan; Chen, Shaw-Ree; Wischnowski, Michael


    A science education center at a university medical school had grant funding to develop a genetics curriculum unit, but needed a dissemination plan. A statewide science teacher organization that provided professional development training was facing decreased funding. These two groups combined their efforts, and created a unique partnership, called…

  10. Museum-University Partnerships as a New Platform for Public Engagement with Scientific Research (United States)

    Bell, Jamie; Chesebrough, David; Cryan, Jason; Koster, Emlyn


    A growing trend in natural history museums, science museums, and science centers is the establishment of innovative new partnerships with universities to bring scientific research to the public in compelling and transformative ways. The strengths of both kinds of institutions are leveraged in effective and publicly visible programs, activities,…

  11. Finding pathways to more equitable and meaningful public-scientist partnerships (United States)

    Daniela Soleri; Jonathan W. Long; Monica D. Ramirez-Andreotta; Ruth Eitemiller; Rajul Pandyaǁ


    For many, citizen science is exciting because of the possibility for more diverse, equitable partnerships in scientific research with outcomes considered meaningful and useful by all, including public participants. This was the focus of a symposium we organized at the 2015 conference of the Citizen Science Association. Here we synthesize points made by symposium...

  12. Extension through Partnerships: Research and Education Center Teams with County Extension to Deliver Programs (United States)

    Mullahey, J. Jeffrey


    Budget reductions have severely affected resources available to deliver agriculture and natural resource Extension programs in Florida. University of Florida/Institute of Food and Agricultural Sciences delivers Extension programming through a unique partnership between research and education centers and county Extension. Science-based information…

  13. Delivering high-level food industry skills for future food security through Advanced Training Partnerships


    Frazier, Richard A.


    The UK Biotechnology and Biological Sciences Research Council’s Advanced Training Partnerships initiative represents a significant investment in the provision of high-level skills for the UK food industry sector to address global food security from farm to fork. This paper summarises the background, aims and scope of the Advanced Training Partnerships, their development so far, and offers a view on future directions and evaluation of impact.

  14. Building a Culture of Authentic Partnership: One Academic Health Center Model for Nursing Leadership. (United States)

    Heath, Janie; Swartz, Colleen


    Senior nursing leaders from the University of Kentucky (UK) College of Nursing and UK HealthCare have explored the meaning of an authentic partnership. This article quantifies the tangible benefits and outcomes from this maturing academic nursing and clinical practice partnership. Benefits include inaugural academic nursing participation in health system governance, expanded integration of nursing research programs both in the college and in the health science center, and the development of collaborative strategies to address nursing workforce needs.

  15. EPA Leadership in the Global Mercury Partnership (United States)

    The Global Mercury Partnership is a voluntary multi-stakeholder partnership initiated in 2005 to take immediate actions to protect human health and the environment from the releases of mercury and its compounds to the environment.

  16. 27 CFR 19.188 - Partnerships. (United States)


    ... partnership is not terminated on death or insolvency of a partner, but continues until the winding up of the... the partnership, he shall qualify in his own name from the date of acquisition, as provided in § 19...

  17. Combined Heat and Power (CHP) Partnership (United States)

    The CHP Partnership seeks to reduce air pollution and water usage associated with electric power generation by promoting the use of CHP. The Partnership works to remove policy barriers and to facilitate the development of new projects.

  18. Design-Build Partnership Attributes Survey Analysis

    National Research Council Canada - National Science Library

    Pyle, Raymond


    Two basic hypotheses were investigated: 1. Finding these attributes for success for a design-build partnership may be accomplished by transferring concepts and ideas from business research on partnership formation. 2...

  19. The Quest for Transformative Partnerships in STEM Education: A Comparison of Policies, Structures and Evaluation Practices (United States)

    Kingsley, G.


    One of the frequent policy prescriptions offered by federal officials for improving science, technology, engineering and mathematics (STEM) education in the United States is to encourage the development of partnerships between higher education, elementary and secondary education, and informal education. This prescription is not unique to STEM education. Rather stimulating the creation and development of partnerships has become one of the preferred strategies for reforming governmental programs through several administrations. This research presents a comparison of several policies designed to stimulate partnerships across multiple organizations. In doing so we examine assumptions about the nature of partnerships embedded in policies and the consequences of these assumptions on the organization and the evaluation of the partnerships. A recurring theme we observe among policies is the quest for transformative partnerships where changing the strategies and behaviors of the participating partners is seen as a necessary, if not sufficient, condition for producing the desired policy outcomes (usually articulated as improving the performance of the school, teacher, student, and even all three). While the goal of policy makers is to achieve transformation, the goal of participating organizations seems to be more instrumental, anchored in their own institutional goals and missions. In this analysis define partnership as voluntary arrangements between organizations, anchored by agreements, to promote the exchange, sharing, or co-development of products and/or programs. The analysis first examines the degree to which policies produce such inter-organizational relationships. Six concepts are drawn for organizational and inter-organizational relations research as a framework for examining the influence of policy upon the pre-conditions for partnership, partnering activities, and the evaluation of partnership performance outcomes. We examine the degree to which policy addresses

  20. JACIE: A Model Partnership (United States)

    Thome, Kurt; Goldberg, Mitch; Mita, Dath; Stensaas, Gregory L.


    The National Aeronautics and Space Administration (NASA), National Oceanic and Atmospheric Administration (NOAA), the United States Department of Agriculture (USDA), and the United States Geological Survey (USGS), and their associates and partners, are directly responsible for establishing and leading a unique interagency team of scientists and engineers who work together to evaluate and enhance the quality remote sensing data for commercial and government use. This team is called "the Joint Agency Commercial Imagery Evaluation (JACIE) team". The team works together to define, prioritize, assign, and assess civil and commercial image quality and jointly sponsors an annual JACIE Civil Commercial Imagery Evaluation workshop with participation support from the remote sensing calibration and validation science community.

  1. The Partnership Pact: Fulfilling School Districts' Research Needs with University-District Partnerships (United States)

    Ralston, Nicole; Weitzel, Bruce; Waggoner, Jacqueline; Naegele, Zulema; Smith, Rebecca


    There has been a recent shift in university-district partnership models from traditional transactional partnerships, which lack a shared purpose, to transformational partnerships that are mutually beneficial to both universities and school districts. These transformational research-practice partnerships have gained popularity in the United States…

  2. Evaluación de la técnica de MSP-PCR para la caracterización molecular de aislamientos de Rhodotorula mucilaginosa provenientes de la Patagonia noroccidental Assessment of the MSP-PCR technique for the molecular characterization of Rhodotorula mucilaginosa isolates from northwestern Patagonia

    Directory of Open Access Journals (Sweden)

    D. Libkind


    Full Text Available La identificación rápida de levaduras de origen ambiental o clínico es de importancia para el estudio de la biodiversidad de estos microorganismos y para la detección de posibles patógenos. Rhodotorula mucilaginosa es una levadura ubicua y pigmentada, capaz de producir infecciones en pacientes inmunocomprometidos. En este trabajo se evaluó la utilidad de la técnica de fingerprinting conocida como MSP-PCR (Micro/Minisatellite-Primed PCR en la caracterización e identificación de aislamientos ambientales de R. mucilaginosa provenientes de la Patagonia noroccidental. Sobre la base de sus caracteres fenotípicos, de un total de 200 levaduras pigmentadas se seleccionaron 110 aislamientos que presuntamente corresponderían a la especie R. mucilaginosa. Se evaluaron los iniciadores (GTG5, (GAC5 y M13 en aislamientos representativos, y se seleccionó el iniciador (GTG5 por ser el que permitió una mejor agrupación de los aislamientos pertenecientes a R. mucilaginosa y una mejor diferenciación de éstos con los de especies filogenéticamente próximas. Utilizando dicho iniciador, el 87% de los aislamientos de R. mucilaginosa presentó un perfil de MSP-PCR similar (> 60% al de la cepa de referencia CBS 316T de R. mucilaginosa. La técnica de MSP-PCR resultó efectiva, tanto para caracterizar e identificar un número elevado de aislamientos ambientales de R. mucilaginosa como para detectar polimorfismos en la especie.The rapid identification of environmental or clinical yeast isolates is important for biodiversity studies and the detection of probable pathogens. Rhodotorula mucilaginosa is a ubiquitous and pigmented yeast capable of infecting immunocompromised patients. In this study, we evaluated the Micro/mini satellite-primed PCR (MSP-PCR fingerprinting method for the characterization and identification of R. mucilaginosa isolates from natural environments in northwestern Patagonia. There were selected 110 putative R. mucilaginosa isolates

  3. Partnerships for corporate social responsability

    NARCIS (Netherlands)

    Bruijn, de T.J.N.M. (Theo)


    The purpose of this paper is to conceptualise the extent to which partnerships with non-governmental organisations (NGOs) are a necessity for successful efforts of businesses in the area of corporate social responsibility (CSR). The main findings are based on an analysis of existing literature on

  4. Renegotiating Public-Private Partnerships

    NARCIS (Netherlands)

    Miranda Sarmento, J.J.; Renneboog, Luc


    The renegotiations of public–private partnership (PPP) contracts are commonly considered to be one of the pitfalls of PPPs, as they tend to undermine their (ex ante) efficiency. A renegotiation occurs when specific events change the conditions of a concession, frequently leading to a financial claim

  5. Information Literacy: Partnerships for Power. (United States)

    Breivik, Patricia Senn; Senn, J. A.


    Describes the partnerships between teacher-librarians and principals, teachers, community members, public librarians, and businesses that school children need to gain information literacy skills. Descriptions, which are adapted from the forthcoming book "Information Literacy: Resources for Elementary School Leaders," include the…

  6. A Model of Partnership Formation

    NARCIS (Netherlands)

    Talman, A.J.J.; Yang, Z.F.


    This paper presents a model of partnership formation. A set of agents wants to conduct some business or other activities. Agents may act alone or seek a partner for cooperation and need in the latter case to consider with whom to cooperate and how to share the profit in a collaborative and

  7. Contemporary Public-private Partnership

    DEFF Research Database (Denmark)

    Hodge, Graeme; Greve, Carsten


    This paper reviews the research agenda lineage on public-private partnerships (PPPs) from Broadbent and Laughlin's seminal piece in 1999. The PPP phenomenon is viewed at five levels: project delivery, organisational form, policy, governance tool and as a phenomenon within a broader historical and...

  8. Business School Partnerships for Globalization (United States)

    Dixon, Rob; Slanickova, Daniela; Warwick, Philip


    International partnerships are an essential tool to enable business schools to internationalize their activities. They can lead to improved research, better more internationally relevant teaching, provide staff with an international perspective, and help prepare students for careers in global business. Using case studies of four of Durham…

  9. A model of partnership formation

    NARCIS (Netherlands)

    Talman, A.J.J.; Yang, Z.F.


    This paper presents a model of partnership formation. A number of agents want to conduct some business or other activities. Agents may act alone or seek a partner for cooperation and need in the latter case to consider with whom to cooperate and how to share the profit in a collaborative and

  10. Research and partnerships with schools. (United States)

    Svirydzenka, Nadzeya; Aitken, Jill; Dogra, Nisha


    Despite the quantity of research on child and adolescent mental health being done in schools, little output has focused on the practical aspects of recruiting schools and students into a study. Furthermore, there is limited knowledge on how to develop and sustain productive and mutually beneficial partnerships with schools after the project finishes. A large study examining prevalence of mental health problems in young people involving nine schools is used as an example for the procedure of recruitment and carrying out a research project, while developing and sustaining partnerships with schools. While recruiting the schools, a three-stage model was developed that corresponded closely to the school's needs and existing demands. The suggested procedure for the study, thus, closely reflected the varying existing cultures of participating schools. Partnerships, developed as a result of the project, were used in developing further projects and interventions for promoting good mental health in schools. Rather than a blanket research recruitment and procedural approach with an end to school involvement at the end of the project, the paper advocates for a deeper understanding of the schools' internal culture for improved recruitment and study outcomes. Developed partnerships, when sustained past the completion of research, prove to be a useful tool in applying the findings in promoting good mental health in schools and continuing research further.

  11. Factors Influencing Donor Partnership Effectiveness

    International Development Research Centre (IDRC) Digital Library (Canada)

    For example, the Centre's support has helped Tanzania reduce child ... how it was developed and applied and what was learned from it. ... case study research. The first was ... into play. 3 For the purpose of the study, a partnership is effective.

  12. Partnership Transitions and Maternal Parenting (United States)

    Beck, Audrey N.; Cooper, Carey E.; McLanahan, Sara; Brooks-Gunn, Jeanne


    We use data from the Fragile Families and Child Wellbeing Study (N = 1,975) to examine the association between mothers' partnership changes and parenting behavior during the first 5 years of their children's lives. We compare coresidential with dating transitions and recent with more distal transitions. We also examine interactions between…

  13. Income trusts and limited partnerships

    International Nuclear Information System (INIS)

    Toews, E.L.


    This author provided a conceptual overview of income trusts and limited partnerships that are designed to pass operating cash flow directly to investors without the imposition of corporate taxes, discussed the evolution of the market, the mechanism used to price income funds, past and present performance of the sector, and made some predictions concerning the sector's future performance. 13 figs

  14. Leveraging Relational Technology through Industry Partnerships. (United States)

    Brush, Leonard M.; Schaller, Anthony J.


    Carnegie Mellon University has leveraged its technological expertise with database management systems (DBMS) into joint technological and developmental partnerships with DBMS and application software vendors. Carnegie's relational database strategy, the strategy of partnerships and how they were formed, and how the partnerships are doing are…

  15. Collaborative Research Partnerships for Knowledge Mobilisation (United States)

    Edelstein, Hilary


    This study examines elements of collaborative research partnerships (CRPs) between university researchers and organisations who engage in knowledge mobilisation activities in education. The study uses key informant interviews and document analysis from one type of partnership, and a survey of university-community partnerships across Canada to…

  16. How to ensure partnerships go wrong


    Peters, Geoff


    This paper is based upon recent academic research on partnership working in a variety of contexts and personal experience of strategic partnerships in the UK. The paper uses examples to draw out some general lessons about when partnerships are likely to succeed and when they may fail.

  17. 15 CFR 806.12 - Partnerships. (United States)


    ... ECONOMIC ANALYSIS, DEPARTMENT OF COMMERCE DIRECT INVESTMENT SURVEYS § 806.12 Partnerships. Limited partners do not have voting rights in a partnership and therefore cannot have a direct investment in a... direct investment in a partnership shall be based on the country of residence of, and the percentage...


    Energy Technology Data Exchange (ETDEWEB)

    Susan M. Capalbo


    The Big Sky Carbon Sequestration Partnership, led by Montana State University, is comprised of research institutions, public entities and private sectors organizations, and the Confederated Salish and Kootenai Tribes and the Nez Perce Tribe. Efforts under this Partnership in Phase I fall into four areas: evaluation of sources and carbon sequestration sinks that will be used to determine the location of pilot demonstrations in Phase II; development of GIS-based reporting framework that links with national networks; designing an integrated suite of monitoring, measuring, and verification technologies and assessment frameworks; and initiating a comprehensive education and outreach program. The groundwork is in place to provide an assessment of storage capabilities for CO{sub 2} utilizing the resources found in the Partnership region (both geological and terrestrial sinks), that would complement the ongoing DOE research. Efforts are underway to showcase the architecture of the GIS framework and initial results for sources and sinks. The region has a diverse array of geological formations that could provide storage options for carbon in one or more of its three states. Likewise, initial estimates of terrestrial sinks indicate a vast potential for increasing and maintaining soil C on forested, agricultural, and reclaimed lands. Both options include the potential for offsetting economic benefits to industry and society. Steps have been taken to assure that the GIS-based framework is consistent among types of sinks within the Big Sky Partnership area and with the efforts of other western DOE partnerships. The Partnership recognizes the critical importance of measurement, monitoring, and verification technologies to support not only carbon trading but all policies and programs that DOE and other agencies may want to pursue in support of GHG mitigation. The efforts in developing and implementing MMV technologies for geological sequestration reflect this concern. Research is

  19. A New Coherent Science Content Storyline Astronomy Course for Pre-Service Teachers at Penn State (United States)

    Palma, Christopher; Plummer, Julia; Earth and Space Science Partnership


    The Earth and Space Science Partnership (ESSP) is a collaboration among Penn State scientists, science educators and seven school districts across Pennsylvania. One of the ESSP goals has been to provide pre-service teachers with new or improved science course offerings at Penn State in the Earth and Space Science domains. In particular, we aim to provide students with opportunities to learn astronomy content knowledge through teaching methods that engage them in investigations where they experience the practices used by astronomers. We have designed a new course that builds on our research into students' ideas about Solar System astronomy (Plummer et al. 2015) and the curriculum our team created for a professional development workshop for in-service teachers (Palma et al. 2013) with this same theme. The course was offered for the first time in the spring 2015 semester. We designed the course using a coherent science content storyline approach (see, e.g., Palma et al. 2014), which requires all of the student investigations to build towards a big idea in science; in this case, we chose the model for formation of our Solar System. The course led pre-service teachers through a series of investigations that model the type of instruction we hope they will adopt in their own classrooms. They were presented with a series of research questions that all tie in to the big idea of Solar System formation, and they were responsible for collecting and interpreting their own data to draw evidence-based conclusions about one aspect of this model. Students in the course were assessed on their astronomy content knowledge, but also on their ability to construct arguments using scientific reasoning to answer astronomy questions. In this poster, we will present descriptions of the investigations, the assessments used, and our preliminary results about how the course led this group of pre-service teachers to improved understanding of astronomy content and the practices astronomers use in

  20. Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern Ghana

    DEFF Research Database (Denmark)

    Amoah, Linda E; Acquah, Festus K; Ayanful-Torgby, Ruth


    BACKGROUND: During a Plasmodium infection, exposure of human host immune cells to both the asexual and the sexual stages of the parasite elicit immune responses. These responses may be protective and prevent the development of high parasitaemia and its associated clinical symptoms, or block...... the transmission of malaria to an uninfected person. This study aimed at examining the dynamics of naturally acquired immune responses against the asexual and sexual forms of Plasmodium falciparum as well as assessing differences in the multiplicity of infection (MOI) in asymptomatic Ghanaian children living...... 2015. Filter paper blood blots (DBS) as well as thick and thin blood smears were made from finger-pricked blood at each visit. Plasmodium falciparum parasite prevalence was determined by microscopy and PCR. Serum eluted from the DBS were used to assess anti-Pfs230 (sexual stage) and anti-MSP3 (asexual...

  1. Chemical display of pyrimidine bases flipped out by modification-dependent restriction endonucleases of MspJI and PvuRts1I families.

    Directory of Open Access Journals (Sweden)

    Evelina Zagorskaitė

    Full Text Available The epigenetic DNA modifications 5-methylcytosine (5mC and 5-hydroxymethylcytosine (5hmC in eukaryotes are recognized either in the context of double-stranded DNA (e.g., by the methyl-CpG binding domain of MeCP2, or in the flipped-out state (e.g., by the SRA domain of UHRF1. The SRA-like domains and the base-flipping mechanism for 5(hmC recognition are also shared by the recently discovered prokaryotic modification-dependent endonucleases of the MspJI and PvuRts1I families. Since the mechanism of modified cytosine recognition by many potential eukaryotic and prokaryotic 5(hmC "readers" is still unknown, a fast solution based method for the detection of extrahelical 5(hmC would be very useful. In the present study we tested base-flipping by MspJI- and PvuRts1I-like restriction enzymes using several solution-based methods, including fluorescence measurements of the cytosine analog pyrrolocytosine and chemical modification of extrahelical pyrimidines with chloroacetaldehyde and KMnO4. We find that only KMnO4 proved an efficient probe for the positive display of flipped out pyrimidines, albeit the method required either non-physiological pH (4.3 or a substitution of the target cytosine with thymine. Our results imply that DNA recognition mechanism of 5(hmC binding proteins should be tested using a combination of all available methods, as the lack of a positive signal in some assays does not exclude the base flipping mechanism.

  2. Epitope-based vaccines with the Anaplasma marginale MSP1a functional motif induce a balanced humoral and cellular immune response in mice.

    Directory of Open Access Journals (Sweden)

    Paula S Santos

    Full Text Available Bovine anaplasmosis is a hemoparasitic disease that causes considerable economic loss to the dairy and beef industries. Cattle immunized with the Anaplasma marginale MSP1 outer membrane protein complex presents a protective humoral immune response; however, its efficacy is variable. Immunodominant epitopes seem to be a key-limiting factor for the adaptive immunity. We have successfully demonstrated that critical motifs of the MSP1a functional epitope are essential for antibody recognition of infected animal sera, but its protective immunity is yet to be tested. We have evaluated two synthetic vaccine formulations against A. marginale, using epitope-based approach in mice. Mice infection with bovine anaplasmosis was demonstrated by qPCR analysis of erythrocytes after 15-day exposure. A proof-of-concept was obtained in this murine model, in which peptides conjugated to bovine serum albumin were used for immunization in three 15-day intervals by intraperitoneal injections before challenging with live bacteria. Blood samples were analyzed for the presence of specific IgG2a and IgG1 antibodies, as well as for the rickettsemia analysis. A panel containing the cytokines' transcriptional profile for innate and adaptive immune responses was carried out through qPCR. Immunized BALB/c mice challenged with A. marginale presented stable body weight, reduced number of infected erythrocytes, and no mortality; and among control groups mortality rates ranged from 15% to 29%. Additionally, vaccines have significantly induced higher IgG2a than IgG1 response, followed by increased expression of pro-inflammatory cytokines. This is a successful demonstration of epitope-based vaccines, and protection against anaplasmosis may be associated with elicitation of effector functions of humoral and cellular immune responses in murine model.

  3. Antibody levels against GLURP R2, MSP1 block 2 hybrid and AS202.11 and the risk of malaria in children living in hyperendemic (Burkina Faso) and hypo-endemic (Ghana) areas

    DEFF Research Database (Denmark)

    Adu, Bright; Cherif, Mariama K; Bosomprah, Samuel


    therefore need to be evaluated against different malaria endemicity backgrounds. METHODS: The associations between antibody responses to the chimeric merozoite surface protein 1 block 2 hybrid (MSP1 hybrid), glutamate-rich protein region 2 (GLURP R2) and the peptide AS202.11, and the risk of malaria were...

  4. Plasmodium vivax Tryptophan Rich Antigen PvTRAg36.6 Interacts with PvETRAMP and PvTRAg56.6 Interacts with PvMSP7 during Erythrocytic Stages of the Parasite.

    Directory of Open Access Journals (Sweden)

    Kriti Tyagi

    Full Text Available Plasmodium vivax is most wide spread and a neglected malaria parasite. There is a lack of information on parasite biology of this species. Genome of this parasite encodes for the largest number of tryptophan-rich proteins belonging to 'Pv-fam-a' family and some of them are potential drug/vaccine targets but their functional role(s largely remains unexplored. Using bacterial and yeast two hybrid systems, we have identified the interacting partners for two of the P. vivax tryptophan-rich antigens called PvTRAg36.6 and PvTRAg56.2. The PvTRAg36.6 interacts with early transcribed membrane protein (ETRAMP of P.vivax. It is apically localized in merozoites but in early stages it is seen in parasite periphery suggesting its likely involvement in parasitophorous vacuole membrane (PVM development or maintenance. On the other hand, PvTRAg56.2 interacts with P.vivax merozoite surface protein7 (PvMSP7 and is localized on merozoite surface. Co-localization of PvTRAg56.2 with PvMSP1 and its molecular interaction with PvMSP7 probably suggest that, PvTRAg56.2 is part of MSP-complex, and might assist or stabilize the protein complex at the merozoite surface. In conclusion, the PvTRAg proteins have different sub cellular localizations and specific associated functions during intra-erythrocytic developmental cycle.

  5. Plasmodium vivax Tryptophan Rich Antigen PvTRAg36.6 Interacts with PvETRAMP and PvTRAg56.6 Interacts with PvMSP7 during Erythrocytic Stages of the Parasite (United States)

    Tyagi, Kriti; Hossain, Mohammad Enayet; Thakur, Vandana; Aggarwal, Praveen; Malhotra, Pawan; Mohmmed, Asif; Sharma, Yagya Dutta


    Plasmodium vivax is most wide spread and a neglected malaria parasite. There is a lack of information on parasite biology of this species. Genome of this parasite encodes for the largest number of tryptophan-rich proteins belonging to ‘Pv-fam-a’ family and some of them are potential drug/vaccine targets but their functional role(s) largely remains unexplored. Using bacterial and yeast two hybrid systems, we have identified the interacting partners for two of the P. vivax tryptophan-rich antigens called PvTRAg36.6 and PvTRAg56.2. The PvTRAg36.6 interacts with early transcribed membrane protein (ETRAMP) of P.vivax. It is apically localized in merozoites but in early stages it is seen in parasite periphery suggesting its likely involvement in parasitophorous vacuole membrane (PVM) development or maintenance. On the other hand, PvTRAg56.2 interacts with P.vivax merozoite surface protein7 (PvMSP7) and is localized on merozoite surface. Co-localization of PvTRAg56.2 with PvMSP1 and its molecular interaction with PvMSP7 probably suggest that, PvTRAg56.2 is part of MSP-complex, and might assist or stabilize the protein complex at the merozoite surface. In conclusion, the PvTRAg proteins have different sub cellular localizations and specific associated functions during intra-erythrocytic developmental cycle. PMID:26954579

  6. Structural, stability, dynamic and binding properties of the ALS-causing T46I mutant of the hVAPB MSP domain as revealed by NMR and MD simulations.

    Directory of Open Access Journals (Sweden)

    Shixiong Lua

    Full Text Available T46I is the second mutation on the hVAPB MSP domain which was recently identified from non-Brazilian kindred to cause a familial amyotrophic lateral sclerosis (ALS. Here using CD, NMR and molecular dynamics (MD simulations, we characterized the structure, stability, dynamics and binding capacity of the T46I-MSP domain. The results reveal: 1 unlike P56S which we previously showed to completely eliminate the native MSP structure, T46I leads to no significant disruption of the native secondary and tertiary structures, as evidenced from its far-UV CD spectrum, as well as Cα and Cβ NMR chemical shifts. 2 Nevertheless, T46I does result in a reduced thermodynamic stability and loss of the cooperative urea-unfolding transition. As such, the T46I-MSP domain is more prone to aggregation than WT at high protein concentrations and temperatures in vitro, which may become more severe in the crowded cellular environments. 3 T46I only causes a 3-fold affinity reduction to the Nir2 peptide, but a significant elimination of its binding to EphA4. 4 EphA4 and Nir2 peptide appear to have overlapped binding interfaces on the MSP domain, which strongly implies that two signaling networks may have a functional interplay in vivo. 5 As explored by both H/D exchange and MD simulations, the MSP domain is very dynamic, with most loop residues and many residues on secondary structures highly fluctuated or/and exposed to bulk solvent. Although T46I does not alter overall dynamics, it does trigger increased dynamics of several local regions of the MSP domain which are implicated in binding to EphA4 and Nir2 peptide. Our study provides the structural and dynamic understanding of the T46I-causing ALS; and strongly highlights the possibility that the interplay of two signaling networks mediated by the FFAT-containing proteins and Eph receptors may play a key role in ALS pathogenesis.


    Directory of Open Access Journals (Sweden)



    Full Text Available The partnership is now increasingly used in all areas thanks to the synergy it implies and of the benefits demonstrated. And in today's economy benefits of the partnership are widely recognized. Partnership in purchase makes no exception. This paper presents the benefits of a partnership-based purchases compared to those of traditional purchasing. Less well known is that a partnership built and/or implemented incorrectly and may result in additional costs and thus lead to disadvantages for both companies. For this reason, the paper aims to present what a partnership is, to show which steps should be taken to build a successful partnership and to exemplify through companies which have implemented correctly this type of collaboration, obtaining exceptional results.

  8. Improving Industry-Relevant Nuclear-Knowledge Development through Special Partnerships

    International Nuclear Information System (INIS)

    Cilliers, A.


    Full text: South African Network for Nuclear Education Science and Technology (SAN NEST) has the objective to develop the nuclear education system in South Africa to a point where suitably qualified and experienced nuclear personnel employed by nuclear science and technology programmes in South Africa are predominantly produced by the South African education system. This is done to strengthen the nuclear science and technology education programmes to better meet future demands in terms of quality, capacity and relevance. To ensure sustainable relevance, it is important to develop special partnerships with industry. This paper describes unique partnerships that were developed with nuclear industry partners. The success of these partnerships has ensured more industry partners to embrace the model which has proven to develop relevant knowledge, support research and provide innovative solutions for industry. (author

  9. Producción y caracterización de un anticuerpo monoclonal que reconoce el fragmento 28-30 kDa de la proteína MSP-1 de Plasmodium falciparum

    Directory of Open Access Journals (Sweden)

    Nina M. Muñoz


    Full Text Available Los merozoitos del parásito Plasmodium falciparum contienen en su superficie los fragmentos producidos por el primer procesamiento proteolítico de la proteina MSP-1 (merozoite surface protein-1. Dichos fragmentos tienen pesos moleculares relativos aproximados de 83, 42, 38 y 28-30 kDa, respectivamente. En este estudio se describe la producción y caracterización de un anticuerpo monoclonal, denominado 8F4, que reconoce la proteina MSP-1 dadas las siguientes características del antigeno: 1 localización subcelular, 2 peso molecular relativo, 3 período de expresión durante el ciclo eritrocítrico, 4 tipo de asociación con la membrana plasmática del parásito y 5 presencia de epítopes compartidos con MSP-1. Adicionalmente. se estableció que 8F4 reconoce el fragmento de 28-30 kDa, producto del primer procesamiento proteolitico de MSP-1. Los análisis realizados permiten confirmar que MSP-1, 28-30 , no permanece en la superficie del merozoito desoués de ocurrida la invasión. lo cual suoiere oue hace oarte del com.o de polipéptidos que es liberado por el merozoito previamente al evento de la invasión. 8F4 es el primer anticuerpo monoclonal reportado hasta el momento que reconoce específicamente este fragmento.

  10. Naturally-acquired humoral immune responses against the N- and C-termini of the Plasmodium vivax MSP1 protein in endemic regions of Brazil and Papua New Guinea using a multiplex assay

    Directory of Open Access Journals (Sweden)

    Alonso Pedro L


    Full Text Available Abstract Background Progress towards the development of a malaria vaccine against Plasmodium vivax, the most widely distributed human malaria parasite, will require a better understanding of the immune responses that confer clinical protection to patients in regions where malaria is endemic. Methods Glutathione S-transferase (GST and GST-fusion proteins representing the N- terminus of the merozoite surface protein 1 of P. vivax, PvMSP1-N, and the C-terminus, PvMSP1-C, were covalently coupled to BioPlex carboxylated beads. Recombinant proteins and coupled beads were used, respectively, in ELISA and Bioplex assays using immune sera of P. vivax patients from Brazil and PNG to determine IgG and subclass responses. Concordances between the two methods in the seropositivity responses were evaluated using the Kappa statistic and the Spearman's rank correlation. Results The results using this methodology were compared with the classical microtitre enzyme-linked immnosorbent assay (ELISA, showing that the assay was sensitive, reproducible and had good concordance with ELISA; yet, further research into different statistical analyses seems desirable before claiming conclusive results exclusively based on multiplex assays. As expected, results demonstrated that PvMSP1 was immunogenic in natural infections of patients from different endemic regions of Brazil and Papua New Guinea (PNG, and that age correlated only with antibodies against the C-terminus part of the molecule. Furthermore, the IgG subclass profiles were different in these endemic regions having IgG3 predominantly recognizing PvMSP1 in Brazil and IgG1 predominantly recognizing PvMSP1 in PNG. Conclusions This study validates the use of the multiplex assay to measure naturally-acquired IgG antibodies against the merozoite surface protein 1 of P. vivax.

  11. CloudSat Education Network: Partnerships for Outreach (United States)

    TeBockhorst, D.


    CloudSat Education Network (CEN): Partnerships to improve the understanding of clouds in formal and informal settings. Since The CloudSat satellite launched in 2006 the Formal and Informal education programs for the mission have been focused on bringing an understanding about the mission science and the importance of clouds, climate & weather science. This has been done by creating and strengthening partnership and collaboration within scientific and educational communities around the country and the world. Because CloudSat was formally recognized as a Earth System Science Pathfinder campaign with the GLOBE program, the CEN developed a set of field protocols for student observations that augmented the GLOBE atmosphere protocols when there was a satellite overpass. This shared process between GLOBE & CloudSat resulted in the training & creation of CEN schools that are both GLOBE schools and CloudSat schools, and also produced three GLOBE partnerships that specialize in cloud science education and outreach. In addition, the CEN has developed productive relationships with other NASA missions and EPO teams. Specifically, in collaboration with the NASA CERES mission projects S'Cool and MyNASAData, we have co-presented at NSTA conferences and with schools participating in a NASA EPOESS-funded formal education project. This collaborative work has been a very real benefit to a wide variety of audiences needing to strengthen their understanding of clouds and their roles in the earth system, and we hope will serve as a model to future missions looking to involve the public in mission science.

  12. Big Sky Carbon Sequestration Partnership

    Energy Technology Data Exchange (ETDEWEB)

    Susan M. Capalbo


    The Big Sky Carbon Sequestration Partnership, led by Montana State University, is comprised of research institutions, public entities and private sectors organizations, and the Confederated Salish and Kootenai Tribes and the Nez Perce Tribe. Efforts under this Partnership in Phase I fall into four areas: evaluation of sources and carbon sequestration sinks that will be used to determine the location of pilot demonstrations in Phase II; development of GIS-based reporting framework that links with national networks; designing an integrated suite of monitoring, measuring, and verification technologies and assessment frameworks; and initiating a comprehensive education and outreach program. The groundwork is in place to provide an assessment of storage capabilities for CO2 utilizing the resources found in the Partnership region (both geological and terrestrial sinks), that would complement the ongoing DOE research agenda in Carbon Sequestration. The region has a diverse array of geological formations that could provide storage options for carbon in one or more of its three states. Likewise, initial estimates of terrestrial sinks indicate a vast potential for increasing and maintaining soil C on forested, agricultural, and reclaimed lands. Both options include the potential for offsetting economic benefits to industry and society. Steps have been taken to assure that the GIS-based framework is consistent among types of sinks within the Big Sky Partnership area and with the efforts of other DOE regional partnerships. The Partnership recognizes the critical importance of measurement, monitoring, and verification technologies to support not only carbon trading but all policies and programs that DOE and other agencies may want to pursue in support of GHG mitigation. The efforts in developing and implementing MMV technologies for geological sequestration reflect this concern. Research is also underway to identify and validate best management practices for soil C in the

  13. Human dimension of strategic partnerships

    Directory of Open Access Journals (Sweden)

    Petković Mirjana M.


    Full Text Available This paper aims to point to the widespread practice of neglecting behavioral aspects of different forms of fusions and integrations of enterprises that have emerged in the process of privatization through strategic partnerships with foreign companies among Serbian enterprises. The initial hypothesis in this paper is that the process of privatization, restructuring and transformation in Serbian enterprises cannot be completely successful and equally advantageous for all the subjects involved if there is no concern for human dimension of these processes. Without this concern there is a possibility for behavioral problems to arise, and the only way to resolve them is through post festum respecting and introducing elements that should never have been neglected in the first place. This paper refers to the phenomenon of collision of cultures and the ways of resolving it while forming strategic partnerships.

  14. Boundary Spanners in Global Partnerships

    DEFF Research Database (Denmark)

    Søderberg, Anne-Marie; Romani, Laurence


    Western companies’ outsourcing of projects to emergent markets is increasingly being replaced by strategic partnerships that require close collaboration between clients and vendors. This study focuses on interorganizational boundary-spanning activities in the context of global information...... client relationships and coordinating highly complex projects. We analyze vendor managers’ narratives of their collaboration with a European client in a long-term project, which is presented as a strategic partnership in an outsourcing 3.0 mode. The study offers a rich and conceptualized account of those......-spanning activities that are reported. The analysis demonstrates the coexistence of transactive and transformative modes of collaboration in the studied case. It reveals both the importance of partner status and the impact of that status on the forms of boundary-spanning activities in which the partners engage...

  15. Partnership as Vehicle for Innovation

    DEFF Research Database (Denmark)

    Jæger, Birgit

    Innovation of public service delivery is currently high at the political agenda in many countries – also within public libraries. Due to the development of digital technologies it is now possible for everybody (with access to the technology) to get access to all kinds of sources of information...... of it is not at all simple and in practice it is quite complicated for a public library to engage in innovative partnerships with external partners. Hence, a project was set up to investigate the drivers and barriers for innovative partnerships and shape a model which public libraries can follow in their work....... In this way the digital development points at the question whether or not libraries have become redundant and must be regarded as a survival from a past society. In 2010 a new strategy for public libraries in Denmark set the goal that the library sector must reinvent the role of libraries to match the needs...

  16. Understanding collaborative partnerships between farmers

    DEFF Research Database (Denmark)

    Asai, Masayasu

    Danish farmers have developed their own strategies to respond to environmental regulations of manure application. Selfgoverning manure exchanges have been widely undertaken by farmers for more than a decade, giving rise to well-established practices. However, there is little factual knowledge about...... the extent and functioning of such existing partnerships between farms as well as farmers’ perceptions of what constitutes successful arrangements. Based on registry and farmer survey data the PhD thesis shows that the vast majority of manure exporters know their partners prior to establishing manure......, duration of the partnership and transport distance. The most important aspects of farmers' perception of successful collaborative arrangements seem to be trust, continuity, flexibility and accessibility. These findings supplement the understanding of farmer collaboration based on spatial-economic models...

  17. Pharmaceutical Public-Private Partnerships

    DEFF Research Database (Denmark)

    Bagley, Constance; Tvarnø, Christina D.


    This article provides a game theory and law-and-management analysis of for- profit pharmaceutical public-private partnerships, a complex type of legal arrangement in the highly regulated pharmaceutical industry. A pharmaceutical public-private partnership (PPPP) agreement is a legally binding...... and a practical perspective on how properly crafted PPPP arrangements can promote innovation more efficiently than traditional self-optimizing contracts. In particular, a properly framed binding contract, coupled with respect for positive incentives, can move the parties away from an inefficient prisoners...... systems to build and share innovation. When coupled with appropriate attention to the difficult task of coordinating the actions of interdependent actors, a PPPP arrangement can enhance the likelihood of successful commercialization of pharmacological discoveries by flipping the par- ties’ incentives...

  18. Developing a transcultural academic-community partnership to arrest obesity. (United States)

    Lee, Rebecca E; Soltero, Erica G; Mama, Scherezade K; Saavedra, Fiorella; Ledoux, Tracey A; McNeill, Lorna


    Innovative and empirically tested strategies are needed to define and understand obesity prevention and reduction in a transcultural society. This manuscript describes the development of Science & Community, a partnership developed over a 3-year period with the end goal of implementing a community-based participatory research (CBPR) trial to reduce and prevent obesity. Outreach strategies focused on promoting the project via existing and new channels and identifying and contacting potential partners using established strategies. Science & Community developed and fostered partnerships by hosting a series of interactive meetings, including three Opportunity Receptions, four Community Open Forum Symposia, and quarterly Community Advisory Board (CAB) meetings. Opportunity Reception (N = 62) and Symposia attendees (N = 103) represented the diversity of the community, and participants reported high satisfaction with content and programming. From these events, the CAB was formed and was comprised of 13 community representatives. From these meetings, a Partnership representing 34 organizations and 614 individuals emerged that has helped to guide the development of future proposals and strategies to reduce obesity in Houston/Harris County.

  19. A Healthy Business Competitioning Partnership


    Aprasing, Andi


    To achieve the development goals the Government continually carry out national development based on the practice of Pancasila which covers all aspects of the life of the nation. Government as the highest power organization authorized to redirect and protect the public in the exercise of its activities through the partnership, sometimes business medium/large businesses treat small businesses not as it should be. That means big business did not help the development of small businesses and even ...

  20. Canada's family violence initiative: partnerships




    Under Canada's four-year, $136 million Family Violence Initiative, the federal government is calling upon all Canadians to work in partnerships towards the elimination of family violence - child abuse, violence against women, and elder (senior) abuse. Family violence is a complex problem and requires the efforts of all Canadians to resolve it. One of the key themes of the Initiative - a multidisciplinary approach to the problem of family violence - is reflected in the selection and developmen...

  1. Essential Partnerships in the Data Management Life Cycle (United States)

    Kinkade, D.; Allison, M. D.; Chandler, C. L.; Copley, N. J.; Gegg, S. R.; Groman, R. C.; Rauch, S.


    An obvious product of the scientific research process is data. Today's geoscience research efforts can rapidly produce an unprecedented volume of multidisciplinary data that can pose management challenges for the facility charged with curating that information. How do these facilities achieve efficient data management in a high volume, heterogeneous data world? Partnerships are critical, especially for small to mid-sized data management offices, such as those dedicated to academic research communities. The idea of partnerships can encompass a wide range of collaborative relationships aimed at helping these facilities meet the evolving needs of their communities. However, one basic and often overlooked partnership in the data management process is that of the information manager and the Principal Investigator (PI) or data originator. Such relationships are critical in discerning the best possible management strategy, and in obtaining the most robust metadata necessary for reuse of multidisciplinary datasets. Partnerships established early in the data life cycle enable efficient management and dissemination of data in high volumes and heterogeneous formats. The Biological and Chemical Oceanography Data Management Office (BCO-DMO) was created to fulfill the data management needs of PIs funded by the NSF Ocean Sciences Biological and Chemical Sections, and Division of Polar Programs. Since its inception, the Office has relied upon the close relationships it cultivates between its data managers and PIs in order to provide effective data management for a wide variety of ecological and biogeochemical oceanographic data. This presentation will highlight some of the successful partnerships BCO-DMO has made with individual and collaborative investigators, as well as those with other data managers representing specific research communities.

  2. Partnership Selection Involving Mixed Types of Uncertain Preferences

    Directory of Open Access Journals (Sweden)

    Li-Ching Ma


    Full Text Available Partnership selection is an important issue in management science. This study proposes a general model based on mixed integer programming and goal-programming analytic hierarchy process (GP-AHP to solve partnership selection problems involving mixed types of uncertain or inconsistent preferences. The proposed approach is designed to deal with crisp, interval, step, fuzzy, or mixed comparison preferences, derive crisp priorities, and improve multiple solution problems. The degree of fulfillment of a decision maker’s preferences is also taken into account. The results show that the proposed approach keeps more solution ratios within the given preferred intervals and yields less deviation. In addition, the proposed approach can treat incomplete preference matrices with flexibility in reducing the number of pairwise comparisons required and can also be conveniently developed into a decision support system.

  3. Learning Partnerships Between Undergraduate Biology Students and Younger Learners

    Directory of Open Access Journals (Sweden)

    Lee Abrahamsen


    Full Text Available In two upper-level elective biology courses and one beginning-level general biology course, college students participated in Learning Partnerships with middle or high school classes to study some aspect of biology. The goals were to enhance learning by providing resources to middle and high school students and teachers and by encouraging college students to consider teaching as a learning tool and a possible career goal. The college students designed lessons, activities, and laboratories that were done at the schools and at Bates College. Feedback and data suggest that the partnerships have helped teachers enrich their curricula, enhanced student learning, encouraged additional high school students to consider applying to college, and encouraged college students to consider teaching science.

  4. Clarifying Parents' and Pediatricians' Views of Partnership. (United States)

    Rapp, Richard C; Pascoe, John


    Given the importance of partnership in improving health care outcomes among children, there is a substantial need to understand better what partnership means to parents and physicians. The goal of this study was to develop a partnership survey that was based on parents' and pediatricians' opinions about the key concepts of partnership. Parents of patients visiting an affluent suburban private practice and a federally qualified health center, and 2 groups of pediatricians, were asked to review 61 partnership concepts and identify those they considered as being important to partnership. Parents and pediatricians from both practices agreed that 42 (68.9%) of the concepts were important to partnership. Sixteen of these concepts were dropped because they were redundant. Parents from both the suburban practice and health center identified 5 (8.2%) concepts that they believed contributed to partnership. Seven (11.5%) concepts were viewed as important to parents and pediatricians from the suburban practice but not to parents from the health center. Significant socioeconomic differences between the 2 parent groups suggested factors that explained the differences between parent groups. The 38 concepts endorsed by parents and pediatricians provided a nuanced view of partnership and formed the Parent Pediatrician Partnership Survey. © Copyright 2016 by the American Board of Family Medicine.

  5. Research on the Mechanism of Science and Technology Infrastructure Resource Sharing Service Based on PPP (Public-Private Partnership) Mode Selection: Taking Chongqing as an Example%基于PPP(公私合作)视角的科技资源共享服务机制研究——以重庆为例的分析

    Institute of Scientific and Technical Information of China (English)

    曾琼; 张小波


    The study found that the root cause of the problems of the existing sharing service management lies in the failure to properly deal with the contradiction between the dual value attributes of public goods and private goodsof science and technology resource.Accordingly,based on the dual value attributesof science and technology infrastructure resource and national policies to encourage social capital to involve in public services,taking Chongqing as a case study,the thesisputs forward the suggestions includingconstructing the management model of sharing service of science and technology infrastructure resourcebased on PPP (public-private partnership) perspective,and setting up the cost-benefit distribution mechanism,coordination management mechanism,resource integration mechanism,reward mechanism,incentive and constraint mechanism and corresponding system to ensure the successful operation of this model.%研究发现,现有科技资源共享服务管理出现问题的根源在于未正确处理好科技资源“公共品”和“私人品”的双重价值属性矛盾.基于此,以重庆为例,充分考虑科技基础资源双重价值属性,结合国家鼓励社会资本参与科研基础设施社会化服务的政策要求,从PPP(公私合作)的视角,构建科技资源共享服务管理模式,建立保证该模式成功运行的成本收益分配机制、协调管理机制、资源整合机制、回报机制、激励与约束机制和相应制度.

  6. Oil sands geologists in an industry-school partnership : a resource and teaching opportunity

    International Nuclear Information System (INIS)

    Dudley, J.S.; Doram, T.


    The province of Alberta has developed a credit course within their Career and Technology Studies Program on the earth science of oil sands for senior high school science students. The course helps students learn to apply basic sciences to earth science through workplace site visits, resource material and team work. This paper described the increasing demand for, and success of, industry-high school partnerships, and provided special emphasis on the Bowness Senior High School-Imperial Oil partnership in Calgary, Alberta. Imperial Oil Resources is a major producer of oil sands and an employer of earth scientists in a variety of careers in which a wide range of technologies is applied. Students enrolled in the credit study program visit the Imperial Oil Resources Research Centre on five different occasions to gain skills and qualities sought by the workplace including communication, adaptability, team work, and science literacy and its application. 9 refs., 1 tab., 2 figs

  7. G8 global partnership. France's contribution

    International Nuclear Information System (INIS)


    Program for Russia (MNEPR) will provide a framework for our cooperation by giving the parties involved the guarantees they need for successfully running the programs. Bilateral cooperation for the disposition of Russian weapons-grade plutonium is covered by a separate arrangement; - cooperation in the chemical field will be organised in the framework of a specific agreement; - cooperation in the biological field is set up through the International Science and Technology Centre (ISTC) in Moscow. Operational management of these cooperation projects has been entrusted to the French Atomic Energy Commission (CEA) in liaison with the General Secretariat for National Defence (SGDN) and the administrations financing these programs: the Ministry of Defence, the Ministry of Foreign Affairs and the Ministry of the Economy, Finance and Industry. As these programs involve a large number of persons, efficient coordination between donors and beneficiaries is essential. For the remediation of the Gremikha site for example the BERD, manager of the NDEP fund, the European Union (through TACIS) and France are coordinating their efforts with ROSATOM. The Contact Expert Group, under the aegis of the IAEA, also contributes to coordination in this field.With regard to dismantling of radioactive sources (RTGs), France is developing a program closely coordinated with Norway. Under the framework of the G8 and through contact with the various contributors and recipients, the Global Partnership Working Group (GPWG) follows up the implementation of these cooperation projects

  8. Pledges of commitment and cooperation in partnerships


    Lachlan Deer; Ralph-C. Bayer


    We use experimental methods to investigate whether pledges of commitment can improve cooperation in endogenously-formed partnerships facing a social dilemma. Treatments vary in terms of the individual's: (1) opportunity to commit to their partner; (2) the cost of dissolving committed partnerships; and (3) the distribution of these dissolution costs between partners. Our findings show that pledges of commitment alone can increase cooperation and welfare in committed partnerships. The introduct...

  9. Partnerships in the Middle East: Interventionist Endeavors?

    DEFF Research Database (Denmark)

    Aarøe Jørgensen, Jakob


    This chapter aims to analyse NATO’s two Middle Eastern and North African (MENA)1 partnership programmes – the Mediterranean Dialogue (MD) and the Istanbul Cooperation Initiative (ICI). The chapter aims to answer the questions: (1) why does NATO engage with MENA partners; (2) what are the obstacles...... that MD and ICI face, and; (3) is the new flexible partnership policy a step towards more constructive Middle Eastern partnerships?...

  10. Scientific Computation Application Partnerships in Materials and Chemical Sciences, Charge Transfer and Charge Transport in Photoactivated Systems, Developing Electron-Correlated Methods for Excited State Structure and Dynamics in the NWChem Software Suite

    Energy Technology Data Exchange (ETDEWEB)

    Cramer, Christopher J. [Univ. of Minnesota, Minneapolis, MN (United States)


    Charge transfer and charge transport in photoactivated systems are fundamental processes that underlie solar energy capture, solar energy conversion, and photoactivated catalysis, both organometallic and enzymatic. We developed methods, algorithms, and software tools needed for reliable treatment of the underlying physics for charge transfer and charge transport, an undertaking with broad applicability to the goals of the fundamental-interaction component of the Department of Energy Office of Basic Energy Sciences and the exascale initiative of the Office of Advanced Scientific Computing Research.

  11. A Graduate Student's Experience and Perspective on a Student-Teacher-Researcher Partnership (United States)

    Bostic, J.; Stylinski, C.; Doty, C.


    Teachers and their K-12 students lack firsthand experience in science research and often harbor misconceptions about science practices and the nature of science. To address this challenge, the NOAA-funded Student-Teacher-Researcher (STAR) partnership that provides rural high school students with authentic research experiences investigating the amount and sources of nitrate in schoolyard runoff. Teachers received training, guiding curricular materials aligned with NGSS and in-classroom support. With a focus on evidence-based reasoning skills, students actively participate in the research process through sample collection, data analysis, and an in-person discussion of conclusions and implications with our scientist team. As a member of this team, I assisted with refining the study design, analyzing nitrate isotope runoff samples, and sharing insights and feedback with students during the in-person discussion session. Assessment results indicate student gained an understanding of nitrate pollution and of science practices. As a graduate student, young scientist, and possessor of a B.S. in Science Education, I already recognized the value of involving K-12 students and teachers in authentic research experiences, as these experiences expose students to the nature of science while also improving content knowledge. During the STAR partnership, I learned firsthand some of the obstacles presented during outreach involving partnerships between a research institution and schools, such as inflexibility of school scheduling and the need for flexibility with research questions requiring complex lab analysis. Additionally, I discovered the challenge of working systemically across a school district, which can have broad impact but limit student experiences. Highlights of my experience included interactions with students and teachers, especially when students have unexpected answers to my questions, providing novel explanations for patterns observed in the data. Despite the

  12. Pledges of Commitment and Cooperation in Partnerships

    Directory of Open Access Journals (Sweden)

    Lachlan Deer


    Full Text Available We use experimental methods to investigate whether pledges of commitment can improve cooperation in endogenously-formed partnerships facing a social dilemma. Treatments vary in terms of the individual’s: (1 opportunity to commit to their partner; (2 the cost of dissolving committed partnerships; and (3 the distribution of these dissolution costs between partners. Our findings show that pledges of commitment alone can increase cooperation and welfare in committed partnerships. The introduction of relatively large and equally split costs yields similar gains. In contrast, when costs to dissolve committed partnerships fall solely on the individual choosing to break up, pledges of commitment fail to improve cooperation and welfare.

  13. Partnership for Sustainable Communities - Grants Map - (United States)

    Department of Transportation — The Partnership for Sustainable Communities is comprised of the Department of Housing and Urban Development (HUD), the US Department of Transportation (DOT), and the...

  14. Information partnerships--shared data, shared scale. (United States)

    Konsynski, B R; McFarlan, F W


    How can one company gain access to another's resources or customers without merging ownership, management, or plotting a takeover? The answer is found in new information partnerships, enabling diverse companies to develop strategic coalitions through the sharing of data. The key to cooperation is a quantum improvement in the hardware and software supporting relational databases: new computer speeds, cheaper mass-storage devices, the proliferation of fiber-optic networks, and networking architectures. Information partnerships mean that companies can distribute the technological and financial exposure that comes with huge investments. For the customer's part, partnerships inevitably lead to greater simplification on the desktop and more common standards around which vendors have to compete. The most common types of partnership are: joint marketing partnerships, such as American Airline's award of frequent flyer miles to customers who use Citibank's credit card; intraindustry partnerships, such as the insurance value-added network service (which links insurance and casualty companies to independent agents); customer-supplier partnerships, such as Baxter Healthcare's electronic channel to hospitals for medical and other equipment; and IT vendor-driven partnerships, exemplified by ESAB (a European welding supplies and equipment company), whose expansion strategy was premised on a technology platform offered by an IT vendor. Partnerships that succeed have shared vision at the top, reciprocal skills in information technology, concrete plans for an early success, persistence in the development of usable information for all partners, coordination on business policy, and a new and imaginative business architecture.

  15. 17 CFR 229.902 - (Item 902) Individual partnership supplements. (United States)


    ... transaction, including, but not limited to, federal income tax consequences, for investors in the partnership... partnership; (iv) Other assets held by the partnership; (v) Other liabilities of the partnership; (vi) The... partnership supplements. 229.902 Section 229.902 Commodity and Securities Exchanges SECURITIES AND EXCHANGE...


    Energy Technology Data Exchange (ETDEWEB)

    Susan M. Capalbo


    The Big Sky Partnership, led by Montana State University, is comprised of research institutions, public entities and private sectors organizations, and the Confederated Salish and Kootenai Tribes and the Nez Perce Tribe. Efforts during the second performance period fall into four areas: evaluation of sources and carbon sequestration sinks; development of GIS-based reporting framework; designing an integrated suite of monitoring, measuring, and verification technologies; and initiating a comprehensive education and outreach program. At the first two Partnership meetings the groundwork was put in place to provide an assessment of capture and storage capabilities for CO{sub 2} utilizing the resources found in the Partnership region (both geological and terrestrial sinks), that would complement the ongoing DOE research. The region has a diverse array of geological formations that could provide storage options for carbon in one or more of its three states. Likewise, initial estimates of terrestrial sinks indicate a vast potential for increasing and maintaining soil C on forested, agricultural, and reclaimed lands. Both options include the potential for offsetting economic benefits to industry and society. Steps have been taken to assure that the GIS-based framework is consistent among types of sinks within the Big Sky Partnership area and with the efforts of other western DOE partnerships. Efforts are also being made to find funding to include Wyoming in the coverage areas for both geological and terrestrial sinks and sources. The Partnership recognizes the critical importance of measurement, monitoring, and verification technologies to support not only carbon trading but all policies and programs that DOE and other agencies may want to pursue in support of GHG mitigation. The efforts begun in developing and implementing MMV technologies for geological sequestration reflect this concern. Research is also underway to identify and validate best management practices for

  17. Partnerships in Nordic Building Industry

    DEFF Research Database (Denmark)

    The project had two main objectives. The first was to establish a Nordic network of people and organisations interested in partnerships and partnering in the building industry in order to facilitate the exchange of experiences and new ideas. This objective was met through a series of workshops......, the functioning of specific partnering tools, knowledge management, training etc. Whereas the growth of partnering in all of the Nordic construction industries has developed from inspiration from the UK, and from other Nordic countries, it is the overall impression that partnering is interpreted, implemented...

  18. Nuclear medicine, a proven partnership

    International Nuclear Information System (INIS)

    Henderson, L. A.


    Full text:Ultrasonography is the modality of choice for demonstrating many cystic structures within the body. However nuclear medicine is often able to demonstrate functional disturbance where ultrasound and conventional radiography are unsuccessful. A case is presented in which a 16 day old male child presented to nuclear medicine with a right upper quadrant cyst found in ultrasound with exact location equivocal. Determining the location and nature of the cyst was essential to the treatment team for patient management. A hepatobiliary study was performed and evidence of a choledochal cyst was found. In partnership with ultrasound, nuclear medicine was able to identify a possibly malignant structure and consequently patient management was determined.

  19. School-industry partnership - Radiation

    International Nuclear Information System (INIS)

    Ruuskanen, Antti


    'Mere are several well-known obstacles to tolerance of nuclear power such as wastes and risks of accident. However, there is a single underlying factor which is, indeed, poorly understood by the general public, namely ionizing radiation. Radiation is one of those natural phenomena not taught to everybody in school. That is why IVO decided to co-operate with schools and teachers, and arrange lessons about radiation. Considering that some parents of pupils follow closely what their children are taught in school, this school-industry partnership may indirectly inform some adults about radiation, too

  20. School-industry partnership - Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Ruuskanen, Antti [IVO Group (Finland)


    'Mere are several well-known obstacles to tolerance of nuclear power such as wastes and risks of accident. However, there is a single underlying factor which is, indeed, poorly understood by the general public, namely ionizing radiation. Radiation is one of those natural phenomena not taught to everybody in school. That is why IVO decided to co-operate with schools and teachers, and arrange lessons about radiation. Considering that some parents of pupils follow closely what their children are taught in school, this school-industry partnership may indirectly inform some adults about radiation, too.

  1. Science commons

    CERN Multimedia

    CERN. Geneva


    SCP: Creative Commons licensing for open access publishing, Open Access Law journal-author agreements for converting journals to open access, and the Scholar's Copyright Addendum Engine for retaining rights to self-archive in meaningful formats and locations for future re-use. More than 250 science and technology journals already publish under Creative Commons licensing while 35 law journals utilize the Open Access Law agreements. The Addendum Engine is a new tool created in partnership with SPARC and U.S. universities. View John Wilbanks's biography

  2. The Trans-Pacific Partnership

    Directory of Open Access Journals (Sweden)

    Voon Tania


    Full Text Available This article provides an overview of the recently concluded Trans-Pacific Partnership Agreement (TPP, a treaty the parties have described as comprehensive and ambitious, yet also representing a balance of competing interests. The article focuses on the TPP’s chapters relating to investment, services, intellectual property and regulatory coherence, each of which provides insight into the motivations that drove the conclusion of the TPP and the negotiating dynamics that determined its final content. In areas such as investment, the TPP takes a more balanced approach than many earlier agreements, providing greater safeguards for the regulatory autonomy of states while still embodying core protections for foreign investors. In relation to intellectual property and services, the TPP goes beyond earlier agreements in several key respects, such as preventing the imposition of local presence requirements for service providers or requiring longer copyright terms than those demanded by other international treaties. The TPP chapter on regulatory coherence is one of the most novel features of the treaty, as regulatory coherence is not frequently included in earlier trade agreements, demonstrating the increased focus of states on addressing regulatory barriers to trade and investment. While all of these elements of the TPP are interesting in their own right, given the number and size of the parties involved in the agreement, they also provide valuable guidance about the direction of other ongoing and future preferential trade agreement negotiations, such as the proposed Transatlantic Trade and Investment Partnership (TTIP and Trade in Services Agreement (TiSA.

  3. Forming mutually beneficial Aboriginal partnerships

    Energy Technology Data Exchange (ETDEWEB)

    Brewster, L.; Shaw, M. [ATCO Frontec, Edmonton, AB (Canada)


    The Alberta-based ATCO Group is engaged in power generation, utilities logistics and energy services and technologies in Alaska, Canada's north, and around the world. In 2001, 56 per cent of ATCO's revenue came from Aboriginal joint ventures. ATCO's foundation for successful partnerships is a mutual trust, an understanding of the environment, and constant communication. The partnerships begin with a long term vision, resulting in community-based northern businesses that benefit Aboriginal partners, shareholders, customers and local staff. This paper described 2 unique joint venture case studies: (1) the north warning system in Cambridge Bay, a radar and communication service for government, and (2) Yellowknife's Tli Cho logistics site for support and municipal services to the mining industry. The north warning system joint venture includes Pan Arctic Inuit Logistics (PAIL), representing Inuvialuit, Labrador, Nunavik and Nunavut, while the Tli Cho joint venture includes participation of the Dog Rib Rae band. Management practices in all joint ventures reflect cultural differences, and Aboriginal people are involved in long term jobs relating to northern pipeline development. 21 figs.

  4. The North Dakota lignite partnership

    International Nuclear Information System (INIS)

    Porter, C.R.


    The State of North Dakota and the Lignite Energy Council have formed a government/industry partnership to promote the use of North Dakota lignite. The partnership provides funding and management for the Lignite Research, Development and Marketing Program. The program funds activities which preserve and enhance jobs and lignite production; ensure economic growth, stability and opportunity; and maintain a stable and competitive tax base. Funding is provided for activities in three areas: marketing feasibility studies, small research projects, and demonstration projects. Funding is derived from the state coal severance tax. Approximately $3,000,000 annually is appropriated from coal severance revenues for program activities. North Dakota is the ninth largest coal producing state, with lignite as the only rank of coal found in the state. Energy is the second largest economic sector in North Dakota, and it currently comprises over 12% of the state's total economic base. This paper reviews the North Dakota lignite industry and describes studies and projects which have received funding from the program

  5. Mapping International University Partnerships Identified by East African Universities as Strengthening Their Medicine, Nursing, and Public Health Programs. (United States)

    Yarmoshuk, Aaron N; Guantai, Anastasia Nkatha; Mwangu, Mughwira; Cole, Donald C; Zarowsky, Christina

    International university partnerships are recommended for increasing the capacity of sub-Saharan African universities. Many publications describe individual partnerships and projects, and tools are available for guiding collaborations, but systematic mappings of the basic, common characteristics of partnerships are scarce. To document and categorize the international interuniversity partnerships deemed significant to building the capacity of medicine, nursing, and public health programs of 4 East African universities. Two universities in Kenya and 2 in Tanzania were purposefully selected. Key informant interviews, conducted with 42 senior representatives of the 4 universities, identified partnerships they considered significant for increasing the capacity of their institutions' medicine, nursing, and public health programs in education, research, or service. Interviews were transcribed and analyzed. Partners were classified by country of origin and corresponding international groupings, duration, programs, and academic health science components. One hundred twenty-nine university-to-university partnerships from 23 countries were identified. Each university reported between 25 and 36 international university partners. Seventy-four percent of partnerships were with universities in high-income countries, 15% in low- and middle-income countries, and 11% with consortia. Seventy percent included medicine, 37% nursing, and 45% public health; 15% included all 3 programs. Ninety-two percent included an education component, 47% research, and 24% service; 12% included all 3 components. This study confirms the rapid growth of interuniversity cross-border health partnerships this century. It also finds, however, that there is a pool of established international partnerships from numerous countries at each university. Most partnerships that seek to strengthen universities in East Africa should likely ensure they have a significant education component. Universities should make

  6. Laboratory/industry partnerships for environmental remediation

    International Nuclear Information System (INIS)

    Beskid, N.J.; Zussman, S.K.


    There are two measures of ''successful'' technology transfer in DOE's environmental restoration and waste management program. The first is remediation of DOE sites, and the second is commercialization of an environmental remediation process or product. The ideal case merges these two in laboratory/industry partnerships for environmental remediation. The elements to be discussed in terms of their effectiveness in aiding technology transfer include: a decision-making champion; timely and sufficient funding; well organized technology transfer function; well defined DOE and commercial markets; and industry/commercial partnering. Several case studies are presented, including the successful commercialization of a process for vitrification of low-level radioactive waste, the commercial marketing of software for hazardous waste characterization, and the application of a monitoring technique that has won a prestigious technical award. Case studies will include: vitrification of low-level radioactive waste (GTS Duratek, Columbia, MD); borehole liner for emplacing instrumentation and sampling groundwater (Science and Engineering Associates, Inc., Santa Fe, NM); electronic cone penetrometer (Applied Research Associates, Inc., South Royalton, VT); and software for hazardous waste monitoring ConSolve, Inc. (Lexington, MA). The roles of the Department of Energy and Argonne National Laboratory in these successes will be characterized

  7. "Who's gonna plant the trees?!?": Creating effective synergies between community and research goals in scientist-community partnerships (United States)

    Declet-Barreto, J.; Johnson, C.


    Harnessing science into effective, community-focused action requires ongoing partnerships that increase both understanding and trust between communities and scientists. One hurdle to overcome is that often, research questions and goals do not line up with the most pressing perceived or objective issues that a partner community faces. Another barrier is that community members often do not have a clear idea of how communities could benefit from the research, an issue that can create confusion and undermine community support for a partnership. In this session, we will discuss some of our successes and misses in developing research partnerships and actionable science for the benefit of communities. We will share stories on how we crafted effective actionable research products in partnership with Environmental Justice and other vulnerable communities.

  8. Theoretical and applied aspects of public-state partnership

    Directory of Open Access Journals (Sweden)

    V. R. Bodelan


    Full Text Available The article summarizes the main approaches to the formation and the development of public-state partnership in foreign countries and in Ukraine. The category «Public-state Partnership» has no clear definition in science, and in public administration it is used in many senses. The lack of theoretical justification, no systematic approach to the separation of theoretical and methodological foundations of the public-state partnerships, the forms of its practical implementation does not allow our country to be competitive internationally. In particular, this applies to such an aspects such as social maturity of business and entrepreneurship. Such companies create NGOs that in many countries provide 3 to 9% of GDP, attract domestic and foreign investments, benefit society and are a form of targeting state impact on the condition and development of social processes and relationships. Ukraine has not yet established the culture of social entrepreneurship, both government authorities and NGOs are not aware how promising such activity authorized by the legislation of Ukraine is. The reserve and the capacity of NGOs when considering formation of a special investment climate, development of production, replenishment of the budgets at all levels, creating conditions for entrepreneurship etc. are not applied. Main role is assigned for the NGOs that make a significant contribution to socio-economic development of the country and become its reliable investment partner.

  9. African Health Sciences

    African Journals Online (AJOL)

    African Health Sciences is an open access, free online, internationally ... by the African Health Journals Partnership Project that is funded by the US National .... Homa Ahmadzia, Sarah Cigna, Imelda Namagembe, Charles Macri, France ... Workers (HEWs) delivering integrated community case management (iCCM) of ...

  10. Partnerships, Governance and Sustainable Development. Reflections on Theory and Practice.

    NARCIS (Netherlands)

    Glasbergen, P.; Biermann, F.; Mol, A.P.J.


    This book explores the process, extent and circumstances under which partnerships can improve the legitimacy and effectiveness of governance for sustainable development. The 'partnership paradigm' is discussed from three distinct perspectives. The first examines partnerships as single collaborative

  11. 75 FR 60771 - Critical Infrastructure Partnership Advisory Council (CIPAC) (United States)


    ... DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS-2010-0080] Critical Infrastructure Partnership... that the meeting may adjourn early if the committee has completed its business. For additional..., Section Chief Partnership Programs, Partnership and Outreach Division, Office of Infrastructure Protection...

  12. Writing about Science for Publication (United States)

    Astin, Christina; Harvey, Clare; Janusz, Stefan


    Can school students get their science research published? Here, we report on an exciting partnership between The Royal Society and "Young Scientists Journal" ("YSJ"), which is written and edited entirely by students aged 12-20. As background, we explore the history and importance of science publishing and the origin of YSJ. The…

  13. Reaping the benefits of biomedical research: partnerships required. (United States)

    Portilla, Lili M; Alving, Barbara


    Reaping the benefits of investments in biomedical research can be achieved most efficiently through active collaboration among industry, academia, government, and nonprofit organizations. The National Institutes of Health (NIH) are exploring multiple ways in which to increase the efficiency of the translational process. Investigators involved in the NIH-funded Clinical and Translational Science Awards are developing public-private partnerships, addressing the barriers to collaboration, training the next generation of interdisciplinary team-oriented researchers, and producing open-source tools for collaboration. NIH is engaging with industry through the Foundation for the NIH and the Small Business Innovation Research Awards.

  14. The Inner Work of Partnership: Tools for Making the Personal Shift from Domination to Partnership

    Directory of Open Access Journals (Sweden)

    Susan Carter


    Full Text Available This article highlights the importance of partnership with oneself in partnership work. Recognizing that partnership is both a process and a practice, the authors bring attention to the role of one’s relationship with self in the partnership model. Ways in which domination thinking becomes internalized and how it functions in our own inner lives is demonstrated. Through a close examination of seven key ways to cultivate a relationship of respect, peace, care, and compassion with self, the authors offer a simple tool to support the practice of partnership values from the inside out.

  15. Lessons learned about coordinating academic partnerships from an international network for health education. (United States)

    Luo, Airong; Omollo, Kathleen Ludewig


    There is a growing trend of academic partnerships between U.S., Canadian, and European health science institutions and academic health centers in low- and middle-income countries. These partnerships often encounter challenges such as resource disparities and power differentials, which affect the motivations, expectations, balance of benefits, and results of the joint projects. Little has been discussed in previous literature regarding the communication and project management processes that affect the success of such partnerships. To fill the gap in the literature, the authors present lessons learned from the African Health Open Educational Resources Network, a multicountry, multiorganizational partnership established in May 2008. The authors introduce the history of the network, then discuss actively engaging stakeholders throughout the project's life cycle (design, planning, execution, and closure) through professional development, relationship building, and assessment activities. They focus on communication and management practices used to identify mutually beneficial project goals, ensure timely completion of deliverables, and develop sustainable sociotechnical infrastructure for future collaborative projects. These activities yielded an interactive process of action, assessment, and reflection to ensure that project goals and values were aligned with implementation. The authors conclude with a discussion of lessons learned and how the partnership project may serve as a model for other universities and academic health centers in high-income countries and low- and middle-income countries that are interested in or currently pursuing international academic partnerships.

  16. Public-private partnerships in translational medicine: concepts and practical examples. (United States)

    Luijten, Peter R; van Dongen, Guus A M S; Moonen, Chrit T; Storm, Gert; Crommelin, Daan J A


    The way forward in multidisciplinary research according to former NIH's director Elias Zerhouni is to engage in predictive, personalized, preemptive and participatory medicine. For the creation of the optimal innovation climate that would allow for such a strategy, public-private partnerships have been widely proposed as an important instrument. Public-private partnerships have become an important instrument to expedite translational research in medicine. The Netherlands have initiated three large public-private partnerships in the life sciences and health area to facilitate the translation of valuable basic scientific concepts to new products and services in medicine. The focus of these partnerships has been on drug development, improved diagnosis and regenerative medicine. The Dutch model of public-private partnership forms the blueprint of a much larger European initiative called EATRIS. This paper will provide practical examples of public-private partnerships initiated to expedite the translation of new technology for drug development towards the clinic. Three specific technologies are in focus: companion diagnostics using nuclear medicine, the use of ultra high field MRI to generate sensitive surrogate endpoints based on endogenous contrast, and MRI guidance for High Intensity Focused Ultrasound mediated drug delivery. Copyright © 2012 Elsevier B.V. All rights reserved.

  17. 78 FR 7997 - Noncompensatory Partnership Options (United States)


    ... Noncompensatory Partnership Options AGENCY: Internal Revenue Service (IRS), Department of the Treasury. ACTION... noncompensatory options and convertible instruments issued by a partnership. The final regulations generally provide that the exercise of a noncompensatory option does not cause the recognition of immediate income...

  18. School-Business Partnerships: Understanding Business Perspectives (United States)

    Badgett, Kevin


    School-business partnerships have been shown to enhance educational experiences for students. There has, however, been limited research demonstrating the priorities and perspectives of for-profit business leaders on those partnerships. In order to address that gap, the researcher interviewed business leaders in two different areas of Texas. After…

  19. The Latest in Corporate-College Partnerships. (United States)

    Meister, Jeanne C.


    Success factors in establishing corporate-college partnerships include communicating a shared vision for success, defining the degree of customization and flexibility from a university, and mutually devising a marketing and recruitment program. The metrics for success must be defined early and managed throughout the partnership. (JOW)

  20. Research partnerships between business researchers and industry

    NARCIS (Netherlands)

    Zalewska-Kurek, Katarzyna; Janßen, Björn; Harms, Rainer


    We study the strategic behaviour of management researchers when establishing research partnerships with industry. To this end we developed a framework distinguishing ‘strategic planned’ and ‘opportunity-driven’ behaviour in the process of establishing and managing research partnerships. We also

  1. Inclusive Partnership: Enhancing Student Engagement in Geography (United States)

    Moore-Cherry, Niamh; Healey, Ruth; Nicholson, Dawn T.; Andrews, Will


    Partnership is currently the focus of much work within higher education and advocated as an important process to address a range of higher education goals. In this paper, we propose the term "inclusive partnership" to conceptualise a non-selective staff-student relationship. While recognising the challenges of inclusive partnership…

  2. The Strategic Partnership between ESO and Australia (United States)

    Comendador Frutos, L.; de Zeeuw, T..; Geeraert, P.


    On 11 July 2017, ESO and the Australian government signed a ten-year Strategic Partnership arrangement giving Australian astronomers access to the La Silla Paranal facilities. The path towards this arrangement is briefly outlined and the details of the Partnership and its implications for both the Australian and ESO astronomical communities are summarised.

  3. Spread the word! Trickle effects of partnerships

    NARCIS (Netherlands)

    Kolk, A.


    Triggered by the many actual partnership activities by organisations in the past fifteen years, both researchers and practitioners have accumulated much knowledge. Most of the shared insights have focused on the partnering organisations and on the societal dimensions of partnerships, the so-called

  4. PEER Business and Industry Partnership (BIP) (United States)

    products laboratories publications nisee b.i.p. members education FAQs links bip members PEER Business and Industry Partnership (BIP) Current BIP members Joining the BIP Program Site Map Search PEER Business and PEER. For an annual donation, the PEER Business and Industry Partnership (BIP) involves members in PEER

  5. Hong Kong's Cross-System University Partnerships (United States)

    Postiglione, Gerard A.; Yunyun, Qin; Te, Alice Y. C.


    The authors examine the special case of Hong Kong higher education's institutional partnerships in the Chinese mainland. After noting the rise of cross-system university partnership in Asia, it provides a neoinstitutional perspective on the differences between the two China higher education systems. Finally, a case study of the experience of the…

  6. Responding to Children's Fears: A Partnership Approach. (United States)

    Sorin, Reesa


    Describes a study into children's fears and suggests that forging partnerships between parents, children, and teachers is one positive step toward addressing fear in young children. Defines partnerships and asserts that they can help in better recognizing fear displays in young children and in sharing ideas about best practice in responding to…

  7. 78 FR 17868 - Noncompensatory Partnership Options; Correction (United States)


    ... or loss by either the issuing partnership or the option holder. The final regulations also modify the... determination of the partners' distributive shares of partnership items. The final regulations also contain a...) to read as follows: Sec. 1.704-1 Partner's distributive share. * * * * * (b) * * * (5) * * * Example...

  8. 78 FR 35559 - Noncompensatory Partnership Options; Correction (United States)


    ... or loss by either the issuing partnership or the option holder. The final regulations also modify the... determination of the partners' distributive shares of partnership items. The final regulations also contain a... distributive share. * * * * * (b) * * * (5) * * * Example 32. * * * (v) * * * Under paragraph (b)(4)(x)(c) of...

  9. Approaches to Partnerships: Who Shares Wins. (United States)

    Further Education Unit, London (England).

    This bulletin identifies and discusses issues surrounding collaborative arrangements and partnerships for British technical colleges and gives guidance on identifying, setting up, and maintaining such arrangements. Some potential advantages and disadvantages of partnerships are listed. A checklist follows of the most common partners in…

  10. Mutual influences of general practitioners in partnerships

    NARCIS (Netherlands)

    Judith, D. de; Groenewegen, Peter P.; Westert, Gert P.


    The aim of this study was to find out whether or not general practitioners (GPs) within the same partnership show more similarities in attitudes and behaviour than GPs in different partnerships, and what the causes of these similarities might be. Knowledge of the causes of patterns of similarities

  11. Partnership Instability, School Readiness, and Gender Disparities (United States)

    Cooper, Carey E.; Osborne, Cynthia A.; Beck, Audrey N.; McLanahan, Sara S.


    Trends in family formation during the past several decades have increased children's exposure to mothers' partnership instability, defined as an entrance into or exit from a coresidential union or a dating partnership. Instability, in turn, is associated with negative outcomes for children and adolescents. This study uses data from the Fragile…

  12. Using Videoconferencing in a School-Scientist Partnership: Students' Perceptions and Scientists' Challenges (United States)

    Falloon, Garry


    This research studied a series of videoconference teaching workshops and virtual labs, which formed a component of a school-scientist partnership involving a New Zealand science research institute and year 13 students at a Wellington high school. It explored students' perceptions of the effectiveness of the videoconferences as an interactive…

  13. When America Makes, America Works A Successful Public Private 3D Printing (Additive Manufacturing) Partnership (United States)


    community within a public-private partnership model to drive an innovation economy forward for the nation. Ad- ditive manufacturing is a game-changer...also is an incredibly powerful teaching tool to reinvigorate Science, Technology, Engineering and Math - ematics—or STEM—education in the United States

  14. Enhancing the "Science" in Elementary Science Methods: A Collaborative Effort between Science Education and Entomology. (United States)

    Boardman, Leigh Ann; Zembal-Saul, Carla; Frazier, Maryann; Appel, Heidi; Weiss, Robinne

    Teachers' subject matter knowledge is a particularly important issue in science education in that it influences instructional practices across subject areas and at different grade levels. This paper provides an overview of efforts to develop a unique elementary science methods course and related field experience through a partnership between…

  15. Sustainability partnerships and viticulture management in California. (United States)

    Hillis, Vicken; Lubell, Mark; Hoffman, Matthew


    Agricultural regions in the United States are experimenting with sustainability partnerships that, among other goals, seek to improve growers' ability to manage their vineyards sustainably. In this paper, we analyze the association between winegrape grower participation in sustainability partnership activities and practice adoption in three winegrowing regions of California. Using data gathered from a survey of 822 winegrape growers, we find a positive association between participation and adoption of sustainable practices, which holds most strongly for practices in which the perceived private benefits outweigh the costs, and for growers with relatively dense social networks. We highlight the mechanisms by which partnerships may catalyze sustainable farm management, and discuss the implications of these findings for improving sustainability partnerships. Taken together, we provide one of the most comprehensive quantitative analyses to date regarding the effectiveness of agricultural sustainability partnerships for improving farm management. Copyright © 2018 Elsevier Ltd. All rights reserved.

  16. A Partnership Training Program in Breast Cancer Diagnosis: Concept Development of the Next Generation Diagnostic Breast Imaging Using Digital Image Library and Networking Techniques

    National Research Council Canada - National Science Library

    Chouikha, Mohamed F


    ...); and Georgetown University (Image Science and Information Systems, ISIS). In this partnership training program, we will train faculty and students in breast cancer imaging, digital image database library techniques and network communication strategy...

  17. NOAA Big Data Partnership RFI (United States)

    de la Beaujardiere, J.


    In February 2014, the US National Oceanic and Atmospheric Administration (NOAA) issued a Big Data Request for Information (RFI) from industry and other organizations (e.g., non-profits, research laboratories, and universities) to assess capability and interest in establishing partnerships to position a copy of NOAA's vast data holdings in the Cloud, co-located with easy and affordable access to analytical capabilities. This RFI was motivated by a number of concerns. First, NOAA's data facilities do not necessarily have sufficient network infrastructure to transmit all available observations and numerical model outputs to all potential users, or sufficient infrastructure to support simultaneous computation by many users. Second, the available data are distributed across multiple services and data facilities, making it difficult to find and integrate data for cross-domain analysis and decision-making. Third, large datasets require users to have substantial network, storage, and computing capabilities of their own in order to fully interact with and exploit the latent value of the data. Finally, there may be commercial opportunities for value-added products and services derived from our data. Putting a working copy of data in the Cloud outside of NOAA's internal networks and infrastructures should reduce demands and risks on our systems, and should enable users to interact with multiple datasets and create new lines of business (much like the industries built on government-furnished weather or GPS data). The NOAA Big Data RFI therefore solicited information on technical and business approaches regarding possible partnership(s) that -- at no net cost to the government and minimum impact on existing data facilities -- would unleash the commercial potential of its environmental observations and model outputs. NOAA would retain the master archival copy of its data. Commercial partners would not be permitted to charge fees for access to the NOAA data they receive, but

  18. Creating responsible partnerships in tourism

    Directory of Open Access Journals (Sweden)

    Ana Spitzer


    Full Text Available RQ: Organisations do not provide sufficient time and effort to seek out companies for partners that would, with the assistance of responsible cooperation, contribute to better quality offers and consequently to increased income and the good reputation of both companies. Responsibilities and ethics is where organizations on bothsides would take on and accept their own norms, tasks, obligations and be aware that in a relationship there is a need to give explanations and justify one’s actions, such partnerships will be long and prosperous. This requires a great deal of knowledge and maturity together with a very important personal characteristic that is care. This study examines whether the creation of long term partnerships through responsible and more personal (friendlyrelations brings the organization to greater success.Purpose: The purpose of this research is to determine how important it is for organizations in the tourism industry to build long term relationships, what it should be based on and whether companies are willing to change the current methods of operations.Method: The method of research was an interview with individuals that had a certain position within a tourism company and had contacts with partners and were obligated to see out new ones. A paradigm model was built and the responses analysed.Results: The survey results are encouraging. The interviews showed that respondents were aware that it is necessary to have long term and responsible partnerships. They recognized that in today’s world there is a lack of collaboration that is based on understanding andthat there should be more relations on a personal level. It isrequired that this changes in the future. The participants specifically highlight financial irresponsibility in many companies that destroys collaboration.Organization: With the help of this study, the author attempts to contribute ideas to organizations on how to create solid collaboration with partners, as

  19. Effects of a partnership support program for couples undergoing fertility treatment. (United States)

    Asazawa, Kyoko


    The study's purpose was to examine the effects of providing a partnership support program. It was designed to improve Japanese couples' partnership, maintain quality of life, decrease psychological distress, and improve marital relationship satisfaction while they underwent infertility treatment that included the possibility of using assisted reproductive technology. This quasi-experimental study with a two-group pretest-post-test design used purposive sampling and non-random assignment of 318 consenting Japanese patients from previous phases of assisted reproductive technology fertility treatment who were patients from a fertility clinic in Tokyo, Japan. The intervention group of 152 patients (76 couples) participated in the partnership support program. The comparison group of 166 patients (83 couples) received usual care. Recruitment was age matched. The program provided information and used a participatory-interactive approach to enhance understanding and cooperation in couples undergoing fertility treatment. The main outcome measures were: "partnership", FertiQoL, Quality Marriage Index, and "psychological distress". There were 311 participants (intervention group n = 148; comparison group, n = 163). The intervention group showed significant improvement in the couples' partnerships and a significant decrease in women's psychological distress using subgroup analysis. The partnership support program provided effective improvement in partnership for the couples, and reduced psychological distress for the women; however, it had less impact for the men. The program was not effective in improving couples' overall quality of life (QOL); however, it was effective in improving the "mind-body" aspects of the QOL subscale. © 2015 The Author. Japan Journal of Nursing Science © 2015 Japan Academy of Nursing Science.

  20. Partnerships: The Key to Sustainability and Reach for E/PO (United States)

    Eisenhamer, Bonnie; McCallister, D.; Ryer, H.


    The Space Telescope Science Institute (STScI) is the home institution for the E/PO activities of the Hubble and future James Webb space telescopes. Over time, STScI’s Office of Public Outreach has established the infrastructure needed for an E/PO program that reaches various audiences at the local, regional, and national levels. Partnerships are a critical element of this infrastructure, and sustainability of our E/PO program is ensured through our ongoing partnerships with organizations and institutions with staying power and reach. We have learned from past efforts that strategic partnerships can foster innovation, support diversity initiatives, and increase impact in a cost-effective way while providing target audiences with greater access to NASA SMD science and resources. Partnerships are utilized to field-test educational products and programs, disseminate materials and initiatives, and support professional development activities. Partners are selected based upon specific criteria such as potential for reach, the percentage of underrepresented educators and students served, complementary program goals, and willingness to collect and share evaluation data and results with us. This poster will highlight examples and benefits of strategic partnerships over time.


    Energy Technology Data Exchange (ETDEWEB)

    Edward N. Steadman; Daniel J. Daly; Lynette L. de Silva; John A. Harju; Melanie D. Jensen; Erin M. O' Leary; Wesley D. Peck; Steven A. Smith; James A. Sorensen


    During the period of October 1, 2003, through September 30, 2005, the Plains CO2 Reduction (PCOR) Partnership, identified geologic and terrestrial candidates for near-term practical and environmentally sound carbon dioxide (CO2) sequestration demonstrations in the heartland of North America. The PCOR Partnership region covered nine states and three Canadian provinces. The validation test candidates were further vetted to ensure that they represented projects with (1) commercial potential and (2) a mix that would support future projects both dependent and independent of CO2 monetization. This report uses the findings contained in the PCOR Partnership's two dozen topical reports and half-dozen fact sheets as well as the capabilities of its geographic information system-based Decision Support System to provide a concise picture of the sequestration potential for both terrestrial and geologic sequestration in the PCOR Partnership region based on assessments of sources, sinks, regulations, deployment issues, transportation, and capture and separation. The report also includes concise action plans for deployment and public education and outreach as well as a brief overview of the structure, development, and capabilities of the PCOR Partnership. The PCOR Partnership is one of seven regional partnerships under Phase I of the U.S. Department of Energy National Energy Technology Laboratory's Regional Carbon Sequestration Partnership program. The PCOR Partnership, comprising 49 public and private sector members, is led by the Energy & Environmental Research Center at the University of North Dakota. The international PCOR Partnership region includes the Canadian provinces of Alberta, Saskatchewan, and Manitoba and the states of Montana (part), Wyoming (part), North Dakota, South Dakota, Nebraska, Missouri, Iowa, Minnesota, and Wisconsin.

  2. Climate in Context - How partnerships evolve in regions (United States)

    Parris, A. S.


    In 2015, NOAA's RISA program will celebrate its 20th year of exploration in the development of usable climate information. In the mid-1990s, a vision emerged to develop interdisciplinary research efforts at the regional scale for several important reasons. Recognizable climate patterns, such as the El Nino Southern Oscillation (ENSO), emerge at the regional level where our understanding of observations and models coalesce. Critical resources for society are managed in a context of regional systems, such as water supply and human populations. Multiple scales of governance (local, state, and federal) with complex institutional relationships can be examined across a region. Climate information (i.e. data, science, research etc) developed within these contexts has greater potential for use. All of this work rests on a foundation of iterative engagement between scientists and decision makers. Throughout these interactions, RISAs have navigated diverse politics, extreme events and disasters, socio-economic and ecological disruptions, and advances in both science and technology. Our understanding of information needs is evolving into a richer understanding of complex institutional, legal, political, and cultural contexts within which people can use science to make informed decisions. The outcome of RISA work includes both cases where climate information was used in decisions and cases where capacity for using climate information and making climate resilient decisions has increased over time. In addition to balancing supply and demand of scientific information, RISAs are engaged in a social process of reconciling climate information use with important drivers of society. Because partnerships are critical for sustained engagement, and because engagement is critically important to the use of science, the rapid development of new capacity in regionally-based science programs focused on providing climate decision support is both needed and challenging. New actors can bolster

  3. Big Sky Carbon Sequestration Partnership

    Energy Technology Data Exchange (ETDEWEB)

    Susan Capalbo


    The Big Sky Carbon Sequestration Partnership, led by Montana State University, is comprised of research institutions, public entities and private sectors organizations, and the Confederated Salish and Kootenai Tribes and the Nez Perce Tribe. Efforts under this Partnership in Phase I are organized into four areas: (1) Evaluation of sources and carbon sequestration sinks that will be used to determine the location of pilot demonstrations in Phase II; (2) Development of GIS-based reporting framework that links with national networks; (3) Design of an integrated suite of monitoring, measuring, and verification technologies, market-based opportunities for carbon management, and an economic/risk assessment framework; (referred to below as the Advanced Concepts component of the Phase I efforts) and (4) Initiation of a comprehensive education and outreach program. As a result of the Phase I activities, the groundwork is in place to provide an assessment of storage capabilities for CO{sub 2} utilizing the resources found in the Partnership region (both geological and terrestrial sinks), that complements the ongoing DOE research agenda in Carbon Sequestration. The geology of the Big Sky Carbon Sequestration Partnership Region is favorable for the potential sequestration of enormous volume of CO{sub 2}. The United States Geological Survey (USGS 1995) identified 10 geologic provinces and 111 plays in the region. These provinces and plays include both sedimentary rock types characteristic of oil, gas, and coal productions as well as large areas of mafic volcanic rocks. Of the 10 provinces and 111 plays, 1 province and 4 plays are located within Idaho. The remaining 9 provinces and 107 plays are dominated by sedimentary rocks and located in the states of Montana and Wyoming. The potential sequestration capacity of the 9 sedimentary provinces within the region ranges from 25,000 to almost 900,000 million metric tons of CO{sub 2}. Overall every sedimentary formation investigated

  4. Challenging the FDA's authority to regulate autologous adult stem cells for therapeutic use: Celltex therapeutics' partnership with RNL Bio, substantial medical risks, and the implications of United States v. Regenerative Sciences. (United States)

    Drabiak-Syed, Katherine


    This Article examines the convergence of three corporations that have attempted to capitalize on translating emerging research into clinical procedures by manufacturing and facilitating the process for patients to obtain mesenchymal stem cell (MSC) injections. Although the Food and Drug Administration (FDA) has asserted its authority to regulate somatic cell therapy products like MSCs under the Public Health Service Act and the Food, Drug, and Cosmetic Act, some manufacturers have attempted to circumvent FDA regulation through various mechanisms and argue that their products do not fall within the definition of a biological product or drug. However, scientific knowledge of using MSCs for clinical therapy remains in its infancy, and MSCs pose a number of serious risks to patients. This Article focuses on the development of Celltex, a company based in Sugar Land, Texas that manufactures and facilitates the injection of autologous MSCs; RNL Bio, a company that licenses its operations technology to Celltex; and Regenerative Sciences, a company based in Broomfield, Colorado that was recently involved in litigation with the FDA. Corporate circumvention of intended regulatory oversight exposes patients to potentially inefficacious products that could contribute to serious medical injuries such as viruses, myocardial infarction, cancer, or death.

  5. Safety and immunogenicity of a malaria vaccine, Plasmodium falciparum AMA-1/MSP-1 chimeric protein formulated in montanide ISA 720 in healthy adults.

    Directory of Open Access Journals (Sweden)

    Jinhong Hu

    Full Text Available BACKGROUND: The P. falciparum chimeric protein 2.9 (PfCP-2.9 consisting of the sequences of MSP1-19 and AMA-1 (III is a malaria vaccine candidate that was found to induce inhibitory antibodies in rabbits and monkeys. This was a phase I randomized, single-blind, placebo-controlled, dose-escalation study to evaluate the safety and immunogenicity of the PfCP-2.9 formulated with a novel adjuvant Montanide ISA720. Fifty-two subjects were randomly assigned to 4 dose groups of 10 participants, each receiving the test vaccine of 20, 50, 100, or 200 microg respectively, and 1 placebo group of 12 participants receiving the adjuvant only. METHODS AND FINDINGS: The vaccine formulation was shown to be safe and well-tolerated, and none of the participants withdrew. The total incidence of local adverse events (AEs was 75%, distributed among 58% of the placebo group and 80% of those vaccinated. Among the vaccinated, 65% had events that were mild and 15% experienced moderate AEs. Almost all systemic adverse reactions observed in this study were graded as mild and required no therapy. The participants receiving the test vaccine developed detectable antibody responses which were boosted by the repeated vaccinations. Sixty percent of the vaccinated participants had high ELISA titers (>1:10,000 of antigen-specific antibodies which could also recognize native parasite proteins in an immunofluorescence assay (IFA. CONCLUSION: This study is the first clinical trial for this candidate and builds on previous investigations supporting PfCP-2.9/ISA720 as a promising blood-stage malaria vaccine. Results demonstrate safety, tolerability (particularly at the lower doses tested and immunogenicity of the formulation. Further clinical development is ongoing to explore optimizing the dose and schedule of the formulation to decrease reactogenicity without compromising immunogenicity. TRIAL REGISTRATION: Chinese State Food and Drug Administration (SFDA 2002SL0046; Controlled

  6. I-LLINI Partnerships for 21st Century Teachers (United States)

    Read, K.; Wong, K.; Charlevoix, D. J.; Tomkin, J.; Hug, B.; Williams, M.; Pianfetti, E.


    I-LLINI Partnerships is two-year State funded program to initiate enhance communication between the faculty at University of Illinois and K-12 teachers in the surrounding communities. The program focuses on math and science with a particular emphasis on the use of technology to teaching math and science to middle-school aged children. The Partnership provides participating teachers with a suite of technology including a computer, digital camera, and software, as well as a small stipend. University partners include representatives from the Departments of Mathematics as well as the Department of Atmospheric Sciences and the Department of Geology. The Atmospheric Sciences and Geology faculty have partnered to provide content using an Earth Systems Science approach to presenting content to the teachers. Additionally, teachers provide feedback to university faculty with relation to how they might better prepare future science teachers. Teacher participants are required to attend a series of workshops during the academic year as well as a summer workshop. The first workshop was held June 2008 on the University of Illinois campus. Our poster will highlight the first workshop providing a discussion and photographs of the activities, an analysis of the benefits and challenges - both to the university representatives as well as the teachers ­ and a summary of future changes planned for the 2009 summer workshop. During the second morning of the workshop, the science teachers participated in an EcoBlitz via a field trip to a collect data from a stream near campus. During the EcoBlitz, math teachers attended tutorial sessions on campus on statistical analysis software. The EcoBliz teachers were provided with instruments and equipment necessary to collect data on the weather conditions and water quality of the stream. Instruments included a temperature probe, turbidity sensor, dissolved oxygen sensor and a hand held weather instrument. Data was recorded with Vernier Lab

  7. Quality partnerships: The community stakeholders' view

    Directory of Open Access Journals (Sweden)

    Vhonani Netshandama


    Full Text Available Since 1997 universities in South Africa have been encouraged to be responsive to the needs of communities, to encourage broader participation and to address issues of access in higher education (Department of Education 1997. This transformative agenda was found to be especially compelling in the case of rural-based South African universities, which often serve historically disadvantaged black populations in areas that are both under-resourced and underdeveloped (Nkomo & Sehoole 2007, pp. 235–36. In 2006 the traditional leadership of a local community approached the University of Venda to propose a partnership. This prompted the researcher to conduct a qualitative study, which sought to explore and describe community members’ views of what they understood to be a quality partnership. Thirty-seven community representatives were engaged in individual as well as focus group interviews. These representatives were identified first through a stakeholder analysis procedure that sought to determine who in the community would have valuable input for the university-community partnership. As a point of departure, the following two questions were asked consecutively: What are your needs and expectations of a partnership with the university and what would you regard as a quality partnership between the HEI and the community? The sample selection was purposive, utilising the snowball technique. Data was transcribed and analysed using Tesch’s eight-step method (Tesch 1990, in Creswell 1994, p. 155. Interview data and field notes were co-coded, crosschecked and triangulated. Feedback workshops were conducted with the community to confirm the findings. A consensus was reached that four main requirements emerged from the data: —Balance the partnership objectives of both parties —Ensure an unexploitative partnership —Share power and control in the partnership —Maintain and monitor the partnership. This article provides a brief overview of the national

  8. Revitalizing a Dying School-Business Partnership


    Martin, Gregory M.


    The notion of business involvement in helping to improve public schools is not new. Although business involvement faded somewhat in the 1960s and 1970s, a resurgence in business involvement began in the late seventies and early eighties. School-business partnerships have been steadily on the rise from around 40,000 in 1983 to over 200,000 by the mid-1990's. When schools and businesses become involved in partnerships certain conditions must be present for the partnerships to succeed. Th...

  9. International partnership in lunar missions

    Indian Academy of Sciences (India)

    related to space science and Moon missions are being addressed in this conference. .... flight. The studies in India suggest that an 'aerobic' space transportation vehicle can indeed have a ... space from Earth at very, very low cost first before.

  10. State and Local Government Partnership

    Energy Technology Data Exchange (ETDEWEB)

    Barton, Alexander; Rinebold, Joel; Aresta, Paul


    The State and Local Government Partnership project has built relationships between the Department of Energy (DOE), regional states, and municipalities. CCAT implemented this project using a structure that included leadership by the DOE. Outreach was undertaken through collaborative meetings, workshops, and briefings; the development of technical models and local energy plans; support for state stakeholder groups; and implementation of strategies to facilitate the deployment of hydrogen and fuel cell technologies. The final guidance documents provided to stakeholders consisted of individual strategic state “Roadmaps” to serve as development plans. These “Roadmaps” confirm economic impacts, identify deployment targets, and compare policies and incentives for facility development in each of the regional states. The partnerships developed through this project have improved the exchange of knowledge between state and local government stakeholders and is expected to increase the deployment of hydrogen and fuel cell technologies in early market applications, consistent with the DOE’s market transformation efforts. Technically accurate and objective information was, and continues to be, provided to improve public and stakeholder perceptions regarding the use of hydrogen and fuel cell technologies. Based on the “Roadmaps” and studies conducted for this project, there is the potential to generate approximately 10.75 million megawatt hours (MWh) of electricity annually from hydrogen and fuel cell technologies at potential host sites in the Northeast regional states, through the development of 1,364 to 1,818 megawatts (MW) of fuel cell electric generation capacity. Currently, the region has approximately 1,180 companies that are part of the growing hydrogen and fuel cell industry supply chain in the region. These companies are estimated to have over $1 billion in annual revenue and investment, contribute more than $51 million in annual state and local tax revenue

  11. 27 CFR 40.64 - Articles of partnership or association. (United States)


    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Articles of partnership or....64 Articles of partnership or association. Every partnership or association, before commencing... § 40.62, a true copy of the articles of partnership or association, if any, or certificate of...

  12. 27 CFR 44.84 - Articles of partnership or association. (United States)


    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Articles of partnership or... Warehouse Proprietors § 44.84 Articles of partnership or association. Every partnership or association... permit, required by § 44.82 a true copy of the articles of partnership or association, if any, or...

  13. 27 CFR 40.495 - Articles of partnership or association. (United States)


    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Articles of partnership or... Manufacturers of Processed Tobacco § 40.495 Articles of partnership or association. Every partnership or... its application for the permit required by § 40.492 a true copy of the articles of partnership or...

  14. 27 CFR 41.235 - Articles of partnership or association. (United States)


    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Articles of partnership or... Importers of Processed Tobacco § 41.235 Articles of partnership or association. Every partnership or... application for the permit required by § 41.231 a true copy of the articles of partnership or association, if...

  15. The Bowie State University Professional Development Schools Network Partnership (United States)

    Garin, Eva; Taylor, Traki; Madden, Maggie; Beiter, Judy; Davis, Julius; Farmer, Cynthia; Nowlin, Dawn


    The Bowie State University PDS Network Partnership is one of the 2015 Exemplary PDS Partnerships recognized by the National Association for Professional Development Schools. This partnership is built on a series of signature programs that define and support our partnership work. This article describes each of those signature programs that make our…

  16. 48 CFR 1401.370 - Acquisition Managers' Partnership. (United States)


    ...' Partnership. 1401.370 Section 1401.370 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... Acquisition Managers' Partnership. (a) The Acquisition Managers' Partnership (AMP) is a forum for DOI's senior... the partnership will meet and develops meeting agendas. The Chairperson will distribute the meeting...

  17. Comparative analysis of partnership behaviors in the National Park Service (United States)

    Melissa S. Weddell; Brett A. Wright; Kenneth F. Backman


    The partnership phenomenon has received considerable attention as an alternative management strategy for public agencies. The growing use of partnerships has created a need to understand key elements of partnership success and failure, how partnerships address park and recreation management paradoxes, and guidelines for best practices (Mowen & Kerstetter, 2006)....


    Directory of Open Access Journals (Sweden)

    Markova V. D.


    Full Text Available The article examines tendencies of the development of new organizational forms of partnership and marks several problems of their usage in Russian conditions by the example of the Novosibirsk region. Modern forms of networking and partnership of commercial companies and universities, research institutes and other organizations, such as clusters, strategic alliances, technology platforms, business ecosystems and other, are focused on the development of new market opportunities and gaining competitive advantage through the sharing of assets and expertise. Two groups of strategic partnership initiatives in the business were emphasized: some initiatives are shown by the state, while some come from the companies. It has been shown that the development of digital technologies, which allows to establish connection between geographically separated participants, promotes the formation of new partnership tools, such as the technology platforms and business ecosystems built on their basis.

  19. Partnership : Information and Communication Technology for ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Partnership : Information and Communication Technology for Development in Africa and Asia ... IDRC invests in research and knowledge to empower women in India ... including heat stress, water management, and climate-related migration.

  20. Project and Partnership Officer | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Job Summary Within the Partnership and Business Development Division led by ... Collaborates in developing and writing proposals for donors;; Participates in ... contracts and grant letters, materiel purchases, travel arrangements, analysis of ...

  1. Green Power Partnership Related Programs & Organizations (United States)

    The U.S. EPA's Green Power Partnership is a voluntary program designed to reduce the environmental impact of electricity generation by promoting renewable energy. This page provides a brief program overview, including vision and accomplishments.

  2. National Clean Fleets Partnership (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)


    Provides an overview of Clean Cities National Clean Fleets Partnership (NCFP). The NCFP is open to large private-sector companies that have fleet operations in multiple states. Companies that join the partnership receive customized assistance to reduce petroleum use through increased efficiency and use of alternative fuels. This initiative provides fleets with specialized resources, expertise, and support to successfully incorporate alternative fuels and fuel-saving measures into their operations. The National Clean Fleets Partnership builds on the established success of DOE's Clean Cities program, which reduces petroleum consumption at the community level through a nationwide network of coalitions that work with local stakeholders. Developed with input from fleet managers, industry representatives, and Clean Cities coordinators, the National Clean Fleets Partnership goes one step further by working with large private-sector fleets.

  3. CEIBS-Fosun Develop Strategic Partnership

    Institute of Scientific and Technical Information of China (English)


      March 1,2005, marked the agreement between the China Europe International Business School(CEIBS) and Fosun Pharmaceuticals as both parties signed the CEIBS-Fosun Strategic Cooperative Partnership Agreement.……

  4. CEIBS-Fosun Develop Strategic Partnership

    Institute of Scientific and Technical Information of China (English)


    @@ March 1,2005, marked the agreement between the China Europe International Business School(CEIBS) and Fosun Pharmaceuticals as both parties signed the CEIBS-Fosun Strategic Cooperative Partnership Agreement.

  5. 27 CFR 555.58 - Continuing partnerships. (United States)


    ... death or insolvency of a partner, but continues until the winding up of the partnership affairs is... obtain a license or permit in his own name from the date of acquisition, as provided in § 555.45. The...

  6. Partnership strategies for safety roadside rest areas. (United States)


    This project studied the many factors influencing the potential for public private partnerships for Safety : Roadside Rest Areas. It found that Federal and California State laws and regulations represent important : barriers to certain types and loca...

  7. Public-private partnership in theory

    Directory of Open Access Journals (Sweden)

    Blaž Vrhnjak


    Full Text Available Background: In political and other debates much of attention is paid to public – private partnerships (PPPs. These partnerships are perceived as a tool of meeting public demand by private supply. In theory there are at least four different forms of contract partnerships according to the amount of risks transferred to the private sector.Conclusions: Public – private partnerships are neither the only neither the preferred way of providing public service. On one hand they tend to lower financial burden of the public sector but on the other hand PPPs require complex ways of management and monitoring. It is highly important to consider specific circumstances of individual projects in question.

  8. Green Power Partnership Frequently Asked Questions (United States)

    The U.S. EPA's Green Power Partnership is a voluntary program designed to reduce the environmental impact of electricity generation by promoting renewable energy. This page provides a brief program overview, including vision and accomplishments.

  9. Green Power Partnership Top 30 Retail (United States)

    EPA's Green Power Partnership is a voluntary program designed to reduce the environmental impact of electricity generation by promoting renewable energy. This list represents the largest green power users among retail partners within the GPP.

  10. Research Awards: Canadian Partnerships Program Deadline: 12 ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Jean-Claude Dumais


    Sep 12, 2012 ... IDRC's Canadian Partnerships (CP) Program offers a Research ... For this, they may consider quantitative and qualitative methods, case studies, ... What types of processes do Canadian organizations use to learn about their ...

  11. Partnership in Opportunities for Employment through Technologies ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Partnership in Opportunities for Employment through Technologies in the ... POETA will work with designated local partners to provide training for youth at risk. ... of the program; a Web-based civic education module for use in POETA centres; ...

  12. INSP: Initiatives and partnerships | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)


    INSP) hosted the International EcoHealth Forum ... INSP sees an ecosystem approach as essential in responding to complex issues in public health. IEF 2008 provided a forum for ideas and partnerships that foster this agenda.

  13. Modeling the hospital safety partnership preferences of patients and their families: a discrete choice conjoint experiment

    Directory of Open Access Journals (Sweden)

    Cunningham CE


    Full Text Available Charles E Cunningham,1 Tracy Hutchings,2 Jennifer Henderson,2 Heather Rimas,1 Yvonne Chen1 1Department of Psychiatry and Behavioural Neurosciences, Faculty of Health Sciences, Michael G DeGroote School of Medicine, McMaster University, 2Department of Quality and Performance, Hamilton Health Sciences, Hamilton, ON, Canada Background: Patients and their families play an important role in efforts to improve health service safety. Objective: The objective of this study is to understand the safety partnership preferences of patients and their families. Method: We used a discrete choice conjoint experiment to model the safety partnership preferences of 1,084 patients or those such as parents acting on their behalf. Participants made choices between hypothetical safety partnerships composed by experimentally varying 15 four-level partnership design attributes. Results: Participants preferred an approach to safety based on partnerships between patients and staff rather than a model delegating responsibility for safety to hospital staff. They valued the opportunity to participate in point of service safety partnerships, such as identity and medication double checks, that might afford an immediate risk reduction. Latent class analysis yielded two segments. Actively engaged participants (73.3% comprised outpatients with higher education, who anticipated more benefits to safety partnerships, were more confident in their ability to contribute, and were more intent on participating. They were more likely to prefer a personal engagement strategy, valued scientific evidence, preferred a more active approach to safety education, and advocated disclosure of errors. The passively engaged segment (26.7% anticipated fewer benefits, were less confident in their ability to contribute, and were less intent on participating. They were more likely to prefer an engagement strategy based on signage. They preferred that staff explain why they thought patients should help

  14. International regularity development partnership (IRDP)

    Energy Technology Data Exchange (ETDEWEB)

    Melani, Ai; Chang, Soon Heung [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)


    Nuclear Energy enters a renaissance era. Several countries consider nuclear as one of their energy resources. For example at the present Vietnam just sign an agreement with Russia for their first nuclear power plants, Malaysia expected that the first nuclear power plant will be operated and commercially available in around the year of 2021. Thailand, Singapore and Indonesia also consider having nuclear power plant in the time frame around 2025. Each country recently tries to prepare their regulatory infrastructure for their first nuclear power plant. The problems are each country doesn't have enough human resource and experience in preparing the nuclear power plant regulations infrastructure. The remains regulations resource is from IAEA which are too general to implement and USNRC which are too detail and difficult to implement for the lack of human resources. Therefore this International Regulatory Development Partnership (IRDP) could be the solutions for the demand of regulatory infrastructure preparations for those countries who's want to emerging nuclear power plant in their country



    Andi Tira


    The principles of economic democracy broke through the overall activities of the society and the State, which sectors of the economy who undertakes by the Constitution as the Foundation of the constitutional business activities in pursuit of national development goals, and is the nation's commitment to the partnership philosophy as well as for businessmen. Although the philosophy of partnership so ideal, but when economic growth is uneven, then it will cause the distance (social inequality) b...

  16. Business Healthy in Competition of Partnership


    Tira, Andi


    The principles of economic democracy broke through the overall activities of the society and the State, which sectors of the economy who undertakes by the Constitution as the Foundation of the constitutional business activities in pursuit of national development goals, and is the nation's commitment to the partnership philosophy as well as for businessmen. Although the philosophy of partnership so ideal, but when economic growth is uneven, then it will cause the distance (social inequality) b...



    Markova V. D.; Trapeznikov I. S.


    The article examines tendencies of the development of new organizational forms of partnership and marks several problems of their usage in Russian conditions by the example of the Novosibirsk region. Modern forms of networking and partnership of commercial companies and universities, research institutes and other organizations, such as clusters, strategic alliances, technology platforms, business ecosystems and other, are focused on the development of new market opportunities and gaining comp...

  18. An Overview of Psychological Research on School-Family Partnership


    小倉, 正義; OGURA, Masayoshi


    These days, the importance of school-family partnership has much understanding. It is valuable forschool-family partnership to promote children's growth, their school progress, and their development.So school-family partnership is one of notable topics in psychological research. The purpose of thisstudy was to overview psychological research on school-family partnership and to discuss the determinantsof school-family relationship and the methods of promoting school-family partnership. In thef...

  19. Archeomagnetic dating of the eruption of Xitle volcano (Mexico) from a reappraisal of the paleointensity with the MSP-DSC protocol. (United States)

    Bravo-Ayala, Manuel; Camps, Pierre; Alva-Valdivia, Luis; Poidras, Thierry; Nicol, Patrick


    The Xitle volcano, located south of Mexico City, is a monogenic volcano that has provided seven lava flows in a time interval of a few years. The age of these eruptions, estimated by means of radiocarbon dates on charcoal from beneath the flows, is still very poorly known, ranging from 4765±90 BC to 520±200 AD (see Siebe, JVGR, 2000 for a review). This lava field was emplaced over the archaeological city of Cuicuilco whose occupation is estimated between 700 BC and 150 AD. Thus a question is still pending: Is the downfall of Cuicuilco directly attributable to the eruption of Xitle? It seems that the answer is negative if we consider the latest radiocarbon dating by Siebe (2000), which sets the age of the eruption to 280±35 AD, that is significantly younger to the abandon of the city. Because this new age has direct implications on the history of the movements of ancient populations in the Central Valley of Mexico, we propose in the present study to check this estimate by archaeomagnetic dating. Xitle lava have been investigated several times for paleomagnetism, including directional analyses and absolute paleointensity determinations (see Alva, EPS, 57, 839-853, 2005 for a review). The characteristic Remanence direction is precisely determined. It is much more difficult to estimate precisely the paleointensity with the Thellier method: values scatter between 40 and 90 μT in a single flow (Alva, 2005). We propose here to estimate the paleointensity by means of the MSP-DSC protocol (Fabian and Leonhardt, 2010) with the new ultra-fast heating furnace FUReMAG developed in Montpellier (France). The sampling was performed along four profiles, one vertical through the entire thickness of the flow and three horizontal (at the top, middle and the bottom of the flow). Our preliminary results show that there is no difference between the values found in the different profiles, all providing a value around 62 μT. The comparison of our results (Dec = 359.0°, Inc = 35.2

  20. Impact of Informal Science Education on Children's Attitudes About Science (United States)

    Wulf, Rosemary; Mayhew, Laurel M.; Finkelstein, Noah D.


    The JILA Physics Frontier Center Partnerships for Informal Science Education in the Community (PISEC) provides informal afterschool inquiry-based science teaching opportunities for university participants with children typically underrepresented in science. We focus on the potential for this program to help increase children's interest in science, mathematics, and engineering and their understanding of the nature of science by validating the Children's Attitude Survey, which is based on the Colorado Learning Attitudes about Science Survey [1] and designed to measure shifts in children's attitudes about science and the nature of science. We present pre- and post-semester results for several semesters of the PISEC program, and demonstrate that, unlike most introductory physics courses in college, our after-school informal science programs support and promote positive attitudes about science.