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Sample records for scandium 59

  1. Scandium fluorides

    International Nuclear Information System (INIS)

    Melnikov, P.; Nalin, M.; Messaddeq, Y.

    1997-01-01

    A new modification of scandium fluoride has been synthesised. The compound is deficient in fluorine, with the composition ScF 2.76 . It belongs to the tetragonal system, lattice parameters being a=3.792 and c=6.740 A and may be obtained at low temperatures by the decomposition of the precursor NH 4 ScF 4 . The reaction is topotactic, tetragonal parameters of the precursor are a=4.021 and c=6.744 A. Structural relationships with various fluorides and ammonium aminofluorides are discussed. This synthesis route with IR-assisted decomposition should be considered as a soft-chemistry approach. (orig.)

  2. Ion exchange purification of scandium

    Science.gov (United States)

    Herchenroeder, Laurie A.; Burkholder, Harvey R.

    1990-10-23

    An improvement in purification of scandium through ion exchange chromatography is disclosed in which the oxidation potential of the eluting solution is altered by the addition of potassium chlorate or ammonium chloride so that removal of contaminants is encouraged. The temperature, pH and concentration of the eluent HEDTA are controlled in order to maintain the scandium in the column while minimizing dilution of the scandium band. Recovery of scandium is improved by pumping dilute scandium over the column prior to stripping the scandium and precipitation. This eliminates the HEDTA ion and other monovalent cations contaminating the scandium band. This method maximizes recovery of scandium while maintaining purity.

  3. Scandium, yttrium and the lanthanides

    International Nuclear Information System (INIS)

    Hart, F.A.

    1987-01-01

    This chapter on the chemistry of the coordination complexes of scandium, yttrium and the lanthanides includes sections on the nitrogen and oxygen donor ligands and complex halides of scandium, and the phosphorus and sulfur donor ligands of yttrium and the lanthanides. Complexes with the macrocylic ligands and with halides are also discussed. Sections on the NMR and electronic spectra of the lanthanides are also included. (UK)

  4. Scandium Terminal Imido Chemistry.

    Science.gov (United States)

    Lu, Erli; Chu, Jiaxiang; Chen, Yaofeng

    2018-02-20

    Research into transition metal complexes bearing multiply bonded main-group ligands has developed into a thriving and fruitful field over the past half century. These complexes, featuring terminal M═E/M≡E (M = transition metal; E = main-group element) multiple bonds, exhibit unique structural properties as well as rich reactivity, which render them attractive targets for inorganic/organometallic chemists as well as indispensable tools for organic/catalytic chemists. This fact has been highlighted by their widespread applications in organic synthesis, for example, as olefin metathesis catalysts. In the ongoing renaissance of transition metal-ligand multiple-bonding chemistry, there have been reports of M═E/M≡E interactions for the majority of the metallic elements of the periodic table, even some actinide metals. In stark contrast, the largest subgroup of the periodic table, rare-earth metals (Ln = Sc, Y, and lanthanides), have been excluded from this upsurge. Indeed, the synthesis of terminal Ln═E/Ln≡E multiple-bonding species lagged behind that of the transition metal and actinide congeners for decades. Although these species had been pursued since the discovery of a rare-earth metal bridging imide in 1991, such a terminal (nonpincer/bridging hapticities) Ln═E/Ln≡E bond species was not obtained until 2010. The scarcity is mainly attributed to the energy mismatch between the frontier orbitals of the metal and the ligand atoms. This renders the putative terminal Ln═E/Ln≡E bonds extremely reactive, thus resulting in the formation of aggregates and/or reaction with the ligand/environment, quenching the multiple-bond character. In 2010, the stalemate was broken by the isolation and structural characterization of the first rare-earth metal terminal imide-a scandium terminal imide-by our group. The double-bond character of the Sc═N bond was unequivocally confirmed by single-crystal X-ray diffraction. Theoretical investigations revealed the presence

  5. Stability constants of scandium complexes, 1

    International Nuclear Information System (INIS)

    Itoh, Hisako; Itoh, Naomi; Suzuki, Yasuo

    1984-01-01

    The stability constants of scandium complexes with some carboxylate ligands were determined potentiometrically at 25.0 and 40.0 0 C and at an ionic strength of 0.10 with potassium nitrate as supporting electrolyte. The constants of the scandium complexes were appreciably greater than those of the corresponding lanthanoid complexes, as expected. The changes in free energy, enthalpy, and entropy for the formation of the scandium complexes were calculated from the stability constants at two temperatures. (author)

  6. Low temperature heat capacity of scandium and alloys of scandium

    Energy Technology Data Exchange (ETDEWEB)

    Tsang, T. W.E.

    1977-12-01

    The heat capacity of three electrotransport purified scandium samples has been measured from 1 to 20/sup 0/K. The resultant electronic specific heat constant and Debye temperature are 10.337 +- 0.015 mJ/gm-atom K/sup 2/ and 346.7 +- 0.8/sup 0/K respectively, and these values are believed to be truly representative of intrinsic scandium. Alloying studies have also been carried out to investigate the band structure of scandium based on the rigid band model, with zirconium to raise the electron concentration and magnesium to lower it. The results are then compared to the theoretical band structure calculations. Low temperature heat capacity measurements have also been made on some dilute Sc-Fe alloys. An anomaly is observed in the C/T vs. T/sup 2/ plot, but the C vs. T curve shows no evidence of magnetic ordering down to 1/sup 0/K, and electrical resistance measurement from 4 to 0.3/sup 0/K also indicates that no magnetic ordering took place.

  7. Extraction of scandium by organic substance melts

    International Nuclear Information System (INIS)

    Gladyshev, V.P.; Lobanov, F.I.; Zebreva, A.I.; Andreeva, N.N.; Manuilova, O.A.; Il'yukevich, Yu.A.

    1984-01-01

    Regularities of scandium extraction by the melts of octadecanicoic acid, n-carbonic acids of C 17 -C 20 commerical fraction and mixtures of tributylphosphate (TBP) with paraffin at (70+-1) deg C have been studied. The optimum conditions for scandium extraction in the melt of organic substances are determined. A scheme of the extraction by the melts of higher carbonic acids at ninitial metal concentrations of 10 -5 to 10 -3 mol/l has been suggested. The scandium compound has been isolated in solid form, its composition having been determined. The main advantages of extraction by melts are as follows: a possibility to attain high distribution coefficients, distinct separation of phases after extraction, the absence of emulsions, elimination of employing inflammable and toxic solvents, a possibility of rapid X-ray fluorescence determinatinon of scandium directly in solid extract

  8. Scandium, yttrium and the lanthanide metals

    International Nuclear Information System (INIS)

    Brown, Paul L.; Ekberg, Christian

    2016-01-01

    The hydroxide and oxide phases that exist for scandium(III) include scandium hydroxide, which likely has both amorphous and crystalline forms, ScOOH(s), and scandium oxide. This chapter presents the data selected for the stability constants of the polymeric hydrolysis species of scandium at zero ionic strength. The behaviour of yttrium, and the lanthanide metals, in the environment is largely dependent on their solution equilibria. Hydrolysis and other complexation reactions of yttrium and the lanthanide metals are important in the disposal of nuclear waste. The trivalent lanthanide metals include lanthanum(III) through lutetium(III). A number of studies have reported a tetrad effect for the geochemical behaviour of the lanthanide series, including stability constants and distribution coefficients. The solubility of many of the lanthanide hydroxide phases has been studied at fixed ionic strength. In studying the hydrolysis of cerium(IV), a number of studies have utilised oxidation-reduction reactions in determining the relevant stability constants.

  9. Extraction of scandium by aromatic carboxylic acids

    International Nuclear Information System (INIS)

    Kamenev, V.F.; Fadeeva, V.I.

    1977-01-01

    Extraction of complex compounds af scandium with salicylic, phenyl- and diphenylacetic acids with chloroform solutions of tetraethyldiamideheptylphosphate as a donor-active additive in relation to the pH and reagent concentration has been studied. Extraction of salicylates of some elements (Ta, Nb, Zr, Hf, Mo) by solutions of tetraethyldiamideheptylphosphate in chloroform has been investigated, and the possibility of their extraction separation from scandium is shown

  10. Extraction of scandium by aromatic carboxylic acids

    Energy Technology Data Exchange (ETDEWEB)

    Kamenev, V F; Fadeeva, V I [Moskovskij Gosudarstvennyj Univ. (USSR)

    1977-04-01

    Extraction of complex compounds af scandium with salicylic, phenyl- and diphenylacetic acids with chloroform solutions of tetraethyldiamideheptylphosphate as a donor-active additive in relation to the pH and reagent concentration has been studied. Extraction of salicylates of some elements (Ta, Nb, Zr, Hf, Mo) by solutions of tetraethyldiamideheptylphosphate in chloroform has been investigated, and the possibility of their extraction separation from scandium is shown.

  11. A basic evaluated neutronic data file for elemental scandium

    International Nuclear Information System (INIS)

    Smith, A.B.; Meadows, J.W.; Howerton, R.J.

    1992-01-01

    This report documents an evaluated neutronic data file for elemental scandium, presented in the ENDF/B-VI format. This file should provide basic nuclear data essential for neutronic calculations involving elemental scandium. No equivalent file was previously available

  12. Method for chromatographically recovering scandium and yttrium

    International Nuclear Information System (INIS)

    Snyder, T.S.; Stoltz, R.A.

    1991-01-01

    This paper describes a method for chromatographically recovering scandium and yttrium from the residue of a sand chlorinator. It comprises: providing a residue from a sand chlorinator, the residue containing scandium, yttrium, sodium, calcium and at least one radioactive metal of the group consisting of radium, thorium and uranium; digesting the residue with an acid to produce an aqueous liquid containing scandium, yttrium, sodium, calcium and at least one radioactive metal of the group consisting of radium, thorium and uranium; feeding the metal containing liquid through a cation exchanger; eluding the cation exchanger with an acid eluant to to produce: a first eluate containing at least half of the total weight of the calcium and sodium in the feed liquid; a second eluate containing at least half of the total weight of the one or more radioactive metals in the feed liquid; a third eluate containing at least half of the yttrium in the feed liquid, and a fourth eluate containing at least half of the weight of the scandium in the feed liquid

  13. Complexometric determination of scandium and aluminium

    International Nuclear Information System (INIS)

    Tikhonov, V.N.

    1980-01-01

    Described is the complexometric determination of scandium and aluminium by the method of reverse titration of EDTA excess by indium salt solution in the presence of the xylenol orange indicator. For the method selectivity increase fluorides are used as a camouflage substance at low pH values (2.5-3.0). The excess fluoride-ions preventing titration are bound by boric acid. Y, Tb, Ti, Zr, Cu, Zn, V, Mo, Co, Cr prevent the determination of Sc and Al

  14. Ternary scandium and transition metals germanides

    International Nuclear Information System (INIS)

    Kotur, B.Ya.

    1992-01-01

    Brief review of data on phase diagram of ternary Sc-Me-Ge systems (Me-d - , f-transition element) is given. Isothermal sections at 870 and 1070 K of 17 ternary systems are plotted. Compositions and their structural characteristics are presented. Variability of crystal structure is typical for ternary scandium germanides: 70 compounds with the studied structure belong to 23 structural types. Ternary germanides isostructural to types of Sm 4 Ge 4 , ZrCrSi 2 , ZrNiAl, ScCeSi, TiNiSi U 4 Re 7 Si 6 145 compounds from 70 under investigation are mostly formed in studied systems

  15. Extraction of scandium salicylate by tetraethyldiamidoheptyl phosphate

    Energy Technology Data Exchange (ETDEWEB)

    Kamenev, V F; Fadeeva, V I; Zyk, N V [Moskovskij Gosudarstvennyj Univ. (USSR). Kafedra Analiticheskoj Khimii

    1976-11-01

    Scandium salicylate is extracted with chloroform in a narrow pH range 3-4 and at the maximum concentration of salicylic acid (H/sub 2/A) in an organic phase, the distribution coefficient reaches 0.1. In the presence of tetraethyldiamideheptylphosphate (DAHP) the zone of maximum extraction grows and the distribution coefficient increases. The ratio of the components in the complex extracted is Sc:H/sub 2/A:DAHPh=1:3:2. The extraction constant is Ksub(ex)=(2.00+-0.02).

  16. Scandium: its occurrence, chemistry, physics, metallurgy, biology, and technology

    International Nuclear Information System (INIS)

    Horovitz, C.T.

    1975-01-01

    This book describes the following aspects of scandium: discovery and history, occurrence in nature, geochemistry and mineralogy, chemical, physical and technological properties, fabrication and metallurgy, its biological significance and toxicology, and its uses. (Extensive references for each chapter)

  17. Interaction of scandium sesquioxide with carbon

    International Nuclear Information System (INIS)

    Vodop'yanov, A.G.; Zakharov, R.G.

    1986-01-01

    In the range of 2350-2470 degrees K at a PCO = 0.0 MPa, interaction in Sc 2 O 3 with carbon mixtures initially occurs by CO chemisorption at the scandium oxide surface and disproportionation into CO 2 and C, with subsequent replacement of oxygen in the oxide anion sublattice by carbon to form ScC. The carbide melt, creating a contact between the reagents, then transforms the process to a diffusion-based one. At 1820-2220 K in vacuum, reduction of the studied mixtures occurs by dissociative vaporization of the oxide, with precipitation of ScC at the carbon surface and generation of CO. The appearance of CO in the vapors of mixture leads to formation of an oxycarbide phase and to the partial occurrence of oxide dissociation

  18. The crystal structure of scandium dyhydrate triglycolate

    International Nuclear Information System (INIS)

    Dukareva, L.M.; Antishkina, A.S.; Porai-Koshits, M.A.; Ostrikova, V.N.; Arkhangel'skij, I.V.; Amanov, A.Z.

    1978-01-01

    The structure of colorless crystals of scandium glycolate dehydrate Sc(CH 2 OHCOO) 3 x2H 2 O, synthesized at the chemical department of MSU has been investigated. Parameters of the monoclinic lattice are determined according to roentgenograms of swing and Kforograms and are specified using the DRON-1 diffractor: a=14.624-+0.005 A; b=13.052-+0.003 A; c=5.730+-0.003 A; γ=96.26 deg+-0.01 deg; rhosub(exper.)=1.09 g/cm 3 ; Z=4; Sp.=P 2/b. Experimental photographic data are obtained using the KFOR chamber. Scannings of the layer lines h anti Ko-h anti K4, containing 742 independent reflexes are taken. Deciphering of the structure is carried out by means of analysis of the Paterson functions distribution and conventional and differential electron densities. Description of the system is presented

  19. Lifetime measurements and oscillator strengths in singly ionized scandium and the solar abundance of scandium

    Science.gov (United States)

    Pehlivan Rhodin, A.; Belmonte, M. T.; Engström, L.; Lundberg, H.; Nilsson, H.; Hartman, H.; Pickering, J. C.; Clear, C.; Quinet, P.; Fivet, V.; Palmeri, P.

    2017-12-01

    The lifetimes of 17 even-parity levels (3d5s, 3d4d, 3d6s and 4p2) in the region 57 743-77 837 cm-1 of singly ionized scandium (Sc II) were measured by two-step time-resolved laser induced fluorescence spectroscopy. Oscillator strengths of 57 lines from these highly excited upper levels were derived using a hollow cathode discharge lamp and a Fourier transform spectrometer. In addition, Hartree-Fock calculations where both the main relativistic and core-polarization effects were taken into account were carried out for both low- and high-excitation levels. There is a good agreement for most of the lines between our calculated branching fractions and the measurements of Lawler & Dakin in the region 9000-45 000 cm-1 for low excitation levels and with our measurements for high excitation levels in the region 23 500-63 100 cm-1. This, in turn, allowed us to combine the calculated branching fractions with the available experimental lifetimes to determine semi-empirical oscillator strengths for a set of 380 E1 transitions in Sc II. These oscillator strengths include the weak lines that were used previously to derive the solar abundance of scandium. The solar abundance of scandium is now estimated to logε⊙ = 3.04 ± 0.13 using these semi-empirical oscillator strengths to shift the values determined by Scott et al. The new estimated abundance value is in agreement with the meteoritic value (logεmet = 3.05 ± 0.02) of Lodders, Palme & Gail.

  20. Highly sensitive luminescence method of scandium determination in the products of metallurgical reprocessing

    International Nuclear Information System (INIS)

    Matveets, M.A.; Akhmetova, S.D.

    1988-01-01

    Highly sensitive reaction of scandium with 1,10-phenanthroline and eosin is used for the development of luminescence method of its determination in metallurgical products. The effect of interfering elements is eliminated by scandium extraction with monocarboxylic acids. The method permits to determine scandium content from 5 x 10 -5 % (Sr 0.15 - 0.25)

  1. Size Effects on Deformation and Fracture of Scandium Deuteride Films.

    Energy Technology Data Exchange (ETDEWEB)

    Teresi, C. S. [Univ. of Minnesota, Minneapolis, MN (United States); Hintsala, E. [Univ. of Minnesota, Minneapolis, MN (United States); Hysitron, Inc., Eden Prairie, MN (United States); Adams, David P. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Yang, Nancy Y. C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kammler, Daniel [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Moody, N. R. [Univ. of Minnesota, Minneapolis, MN (United States); Gerberich, W. W. [Univ. of Minnesota, Minneapolis, MN (United States)

    2017-07-01

    Metal hydride films have been observed to crack during production and use, prompting mechanical property studies of scandium deuteride films. The following focuses on elastic modulus, fracture, and size effects observed in the system for future film mechanical behavior modeling efforts. Scandium deuteride films were produced through the deuterium charging of electron beam evaporated scandium films using X-ray diffraction, scanning Auger microscopy, and electron backscatter diffraction to monitor changes in the films before and after charging. Scanning electron microscopy, nanoindentation, and focused ion beam machined micropillar compression tests were used for mechanical characterization of the scandium deuteride films. The micropillars showed a size effect for flow stress, indicating that film thickness is a relevant tuning parameter for film performance, and that fracture was controlled by the presence of grain boundaries. Elastic modulus was determined by both micropillar compression and nanoindentation to be approximately 150 GPa, Fracture studies of bulk film channel cracking as well as compression induced cracks in some of the pillars yielded a fracture toughness around 1.0 MPa-m1/2. Preliminary Weibull distributions of fracture in the micropillars are provided. Despite this relatively low value of fracture toughness, scandium deuteride micropillars can undergo a large degree of plasticity in small volumes and can harden to some degree, demonstrating the ductile and brittle nature of this material

  2. Formation of scandium carbides and scandium oxycarbide from the elements at high-(P, T) conditions

    International Nuclear Information System (INIS)

    Juarez-Arellano, Erick A.; Winkler, Bjoern; Bayarjargal, Lkhamsuren; Friedrich, Alexandra; Milman, Victor; Kammler, Daniel R.; Clark, Simon M.; Yan Jinyuan; Koch-Mueller, Monika; Schroeder, Florian; Avalos-Borja, Miguel

    2010-01-01

    Synchrotron diffraction experiments with in situ laser heated diamond anvil cells and multi-anvil press synthesis experiments have been performed in order to investigate the reaction of scandium and carbon from the elements at high-(P,T) conditions. It is shown that the reaction is very sensitive to the presence of oxygen. In an oxygen-rich environment the most stable phase is ScO x C y , where for these experiments x=0.39 and y=0.50-0.56. If only a small oxygen contamination is present, we have observed the formation of Sc 3 C 4 , Sc 4 C 3 and a new orthorhombic ScC x phase. All the phases formed at high pressures and temperatures are quenchable. Experimentally determined elastic properties of the scandium carbides are compared to values obtained by density functional theory based calculations. - Graphical Abstract Legend (TOC Figure): Table of Contents Figure Selected images recorded with a MAR345 image plate detector show the reaction of α-Sc and graphite at high-(P,T) conditions. Left: mixture of α-Sc and graphite. Right: recovered sample after laser heated the diamond anvil cell.

  3. Smelting of Scandium by Microwave Irradiation

    Directory of Open Access Journals (Sweden)

    Satoshi Fujii

    2017-09-01

    Full Text Available Scandium is being explored as an alloying element for aluminum alloys, which are gaining importance as high-performance lightweight structural alloys in the transportation industry. A few years ago, Sc was also found to be suitable for use in electrical devices. High-Sc-content ScAlN thin films have attracted significant attention because of their strong piezoelectricity. The piezoelectric response of ScAlN suggests that ScAlN thin films formed on a hard substrate would be suitable surface acoustic wave wideband filters for next-generation wireless communication systems. However, it is often difficult to use ScAlN thin films in MEMS devices—including acoustic ones—because of the extremely high price of metallic Sc, given the difficulty associated with smelting it. Here, we propose a novel process for smelting Sc metal by microwave irradiation. Sc metal was able to be obtained successfully from ScF3 through a microwave-irradiation-based carbon reduction reaction. The reaction temperature for this reduction process was approximately 880°C, which is half of that for the conventional smelting process involving reduction with Ca. Thus, the proposed microwave irradiation process has significant potential for use in the smelting of Sc metal.

  4. Scandium and zirconium ion complexing with salicylic acid

    International Nuclear Information System (INIS)

    Fadeeva, V.I.; Kochetkova, S.K.

    1979-01-01

    A study has been made of the extraction of complexes containing scandium and zirconium compounds and salicylic acid by using benzene, nitrobenzene, chloroform and isoamyl alcohol. It is shown that in the metal concentration range 10 -5 -10 -3 mole/l scandium forms mononuclear complexes composed of Sc(HSal) 3 (pH 2 (pH>4), zirconium - polynuclear complexes Zrsub(x)(OH)sub(y)(HSal)sub(n), where the x:n ratio varies from 0.5 to 1.5. Stability constants have been calculated for the salicylate scandium complexes in aqueous solution, equal to β 1 =(3+-1)x10 2 ; β 2 =(5.0+-0.6)x10 4 ; β 3 =(5.3+-0.3)x10 6

  5. Scandium and zirconium ion complexing with salicylic acid

    Energy Technology Data Exchange (ETDEWEB)

    Fadeeva, V I; Kochetkova, S K [Moskovskij Gosudarstvennyj Univ. (USSR)

    1979-08-01

    A study has been made of the extraction of complexes containing scandium and zirconium compounds and salicylic acid by using benzene, nitrobenzene, chloroform and isoamyl alcohol. It is shown that in the metal concentration range 10/sup -5/-10/sup -3/ mole/l scandium forms mononuclear complexes composed of Sc(HSal)/sub 3/ (pH<=4) and Sc(OH)(HSal)/sub 2/ (pH>4), zirconium - polynuclear complexes Zrsub(x)(OH)sub(y)(HSal)sub(n), where the x:n ratio varies from 0.5 to 1.5. Stability constants have been calculated for the salicylate scandium complexes in aqueous solution, equal to ..beta../sub 1/=(3+-1)x10/sup 2/; ..beta../sub 2/=(5.0+-0.6)x10/sup 4/; ..beta../sub 3/=(5.3+-0.3)x10/sup 6/.

  6. Scandium/carbon filters for soft x rays

    NARCIS (Netherlands)

    Artioukov, IA; Kasyanov, YS; Kopylets, IA; Pershin, YP; Romanova, SA

    2003-01-01

    This Note deals with thin-film soft x-ray filters for operation at the wavelengths near carbon K edge (similar to4.5 nm). The filters were fabricated by magnetron sputtering deposition of thin layers of scandium (total thickness 0.1-0.2 mum) onto films of polypropylene (thickness 1.5 mum) and

  7. Heat capacity and solid solubility of iron in scandium

    International Nuclear Information System (INIS)

    Tsang, T.-W.E.

    1981-01-01

    The maximum solid solubility of iron in scandium was determined to be between 50 and 85 at.ppm in the as-cast condition. As the concentration of iron increases, it segregates along the grain boundary, as is evident from optical metallography and electron microprobe examinations. Annealing also causes the iron dissolved in scandium to separate out and cluster along the grain boundary. Heat capacity measurements show an anomaly in the C/T versus T 2 plots for iron concentrations of 19 at.ppm or greater. For iron dissolved in solid scandium the excess entropy due to the iron impurity is in agreement with the theoretical prediction of ck ln(2S + 1) for an impurity-conduction electron (Kondo) interaction, but is 4 - 8 times larger than the theoretical prediction when iron segregates along the grain boundary. Furthermore, our results suggest that most of the previously reported low temperature physical properties of scandium are probably in error because of either iron impurity-conduction electron interactions or Fe-Fe interactions in the precipitated second-phase Sc-Fe compound. (Auth.)

  8. Thermoelectric material comprising scandium doped zinc cadmium oxide

    DEFF Research Database (Denmark)

    2016-01-01

    There is presented a composition of scandium doped Zinc Cadmium Oxide with the general formula ZnzCdxScyO which the inventors have prepared, and for which material the inventors have made the insight that it is particularly advantageous as an n-type oxide material, such as particularly advantageous...

  9. Synthesis and properties of scandium ortho-phosphate

    International Nuclear Information System (INIS)

    Eshchenko, L.S.; Pechkovskij, V.V.; Dvoskina, R.N.

    1979-01-01

    With the aim to elucidate the influence of synthesis conditions on the chemical composition and properties of orthophosphates of scandium, the interaction of orthophosphoric acid and scandium-containing component (oxide or salt) was studied under various conditions. In the interaction of scandium salt, phosphoric acid and ammonia at room temperature and pH 3.0; 5.0; 7.0 and 9.0 amorphous scandium phosphates have been obtained with the composition of x Sc 2 O 3 xY P 2 O 5 xz NH 3 xn H 2 O. After prolonged staying in mother liquor, roentgenoamorphous precipitates of phosphates transform into the crystalline state. The dependences are studied of the specific surface of amorphous phosphates on pH of precipitation and temperature of the heat treatment (200-800 deg C). Precipitates obtained in a neutral medium at 400 deg C temperature of thermal treatment, show a maximum specific surface. At a temperature of 820-840 deg C the crystallization of amorphous phase occurs followed by the recrystallization and formation of anhydrous SePO 4 of zircon type

  10. Characterization and excitation behaviour studies of radionuclide (scandium) in glass matrix

    International Nuclear Information System (INIS)

    Rehana, Ishrat; Shahid, K.A.; Husain, S.; Muhammad, Din

    1999-01-01

    Directional movements of bed load in marine sediments are studied using a radioactive tracer, scandium, similar to the natural sediment in the area. Scandium glass prepared for this purpose was analyzed by atomic emission spectrography for quality assurance purposes. A buffer composed of graphite with 5% germanium oxide was used for accurate and reproducible analyses. The role of this buffer in the excitation behavior of scandium and variations in spectral line intensity with respect to various influencing parameters are reported. Volatilization of scandium was observed using the moving plate technique, with a dc-arc as the excitation source

  11. Scandium - problem of ultra-trace-element essentiality

    International Nuclear Information System (INIS)

    Kist, A.A.; Zkuk, L.I.; Danilova, E.A.; Makhmudov, E.A.

    2006-01-01

    Full text: Role of constitutional and essential elements in Life is known quite well. It is also well known that all chemical elements present in the living matter. Nevertheless essentiality of at least 55 chemical elements (more than a half of number of natural elements) is still not accepted. In many cases these elements presumably play important role in the Life. On the other hand their essentiality is still under doubt. One of the 'strange' elements in this connection is scandium. Scandium is an element which is very 'simple' for instrumental neutron activation analysis (INAA). For many years in our laboratory were carried out studies on animals and human tissues and fluids elemental composition using INAA in which data for scandium were obtained as 'redundant' information. Essentiality of scandium was newer proven using accepted criteria of elements. Nevertheless in our studies were found various regularities, statistically significant inter-elemental correlations and correlations between elements in tissues and fluids versus clinic and biochemical data. There are some examples. There were found correlations of scandium hair concentration and blood glucose (r=0.68±0.13), body mass index (r=0.86±0.07), leukocyte with phagocytic activity migration inhibition test (r=0.68±0.18), size of cavity of the left heart auricle (r=-0.65±0.16), final systolic bulk (r=0.80±0.12), stroke output of heart (r=-0.79±0.12), final diastolic bulk (0.88±0.0080) etc. In addition using gel filtration in rat liver cytosol was found peak of scandium in elution curve. Examples and correlations given in the paper say in favor that scandium may play quite important role in biological processes and that the biological role of scandium should be studied more intensive. The most important criterion is an appearance of the organism dysfunction in case of removal of the studied elements from the diet (intake) which in all other sides remains completely valuable and disappearance of all

  12. Complexing of scandium with eriochromecyanine R and cetyltrimethylammonium

    International Nuclear Information System (INIS)

    Tikhonov, V.N.; Samarkina, T.V.

    1978-01-01

    Complexing of scandium with eriochromecyanine R (ECC) in the presence of cetyltrimethylammonium (CTA) is studied. At optimum value of pH 6.2 a three-component complex of blue colour is forming with the Sc:ECC:CTA = 1:3:5 relation of compounds. Lambdasub(max) for the complex varies from 585 to 615 nm, molarabsorption coefficient is equal to (1.48+-0.02)x10 5 . A method of photometric determination of Sc with ECC and CTA is suggested. Even considerable quantities of Mg, Ca, Sr, Zn, Cd, La, Mn, Ni do not affect the Sc determination, whereas Cu, Be, Al, Ga, Fe(3) and Pd(2) affect it to a great degree even in relation of 1:1. Camouflaging substances such as fluorides, citrates, tartrates and EDTA prevent from scandium complexing, that is why they should not be used to increase the determination selectivity

  13. Incommensurate composite crystal structure of scandium-II

    International Nuclear Information System (INIS)

    Fujihisa, Hiroshi; Gotoh, Yoshito; Yamawaki, Hiroshi; Sakashita, Mami; Takeya, Satoshi; Honda, Kazumasa; Akahama, Yuichi; Kawamura, Haruki

    2005-01-01

    The long-unknown crystal structure of the high pressure phase scandium-II was solved by powder x-ray diffraction and was found to have tetragonal host channels along the c axis and guest chains that are incommensurate with the host, as well as the high pressure phases of Ba, Sr, Bi, and Sb. The pressure dependences of the lattice constants, the incommensurability, the atomic distances, and the atomic volume were investigated

  14. Tetragonal ternary borides: superconductivity, ferromagnetism and the role of scandium

    International Nuclear Information System (INIS)

    Matthias, B.T.; Patel, C.K.N.; Barz, H.; Corenzwit, E.; Vandenberg, J.M.

    1978-01-01

    The authors report and discuss two discoveries made while studying the condensation phenomena of ternary rhodium borides, MRh 4 B 4 . M is generally a trivalent transition metal, usually a rare earth element RE. An exception is scandium which by itself does not form an isomorphous boride, but in combination with many other elements will do just that. A suprising correlation between ferromagnetic and superconducting transition temperatures has been found. (Auth.)

  15. Determination of scandium with salicylaldehyde and 2-aminobenzenearsonic acid

    International Nuclear Information System (INIS)

    Farias, P.A.M.; Hainberger, L.; Andrade, H.A.S.

    1984-01-01

    A new method for the spectrophotometric determination of scandium by means of a coloured complex formed with salicylaldehyde and 2-aminobenzenearsonic acid is described. Lambert-Beer's law is followed in the range of 0.2 - 2.0 μg/ml of the final solution. The maximum amounts of 39 ions that may be present without interfering in the method are listed. (Author) [pt

  16. The characteristics of aluminum-scandium alloys processed by ECAP

    International Nuclear Information System (INIS)

    Venkateswarlu, K.; Rajinikanth, V.; Ray, Ajoy Kumar; Xu Cheng; Langdon, Terence G.

    2010-01-01

    Aluminum-scandium alloys were prepared having different scandium additions of 0.2, 1.0 and 2.0 wt.% and these alloys were processed by equal-channel angular pressing (ECAP) at 473 K. The results show the grain refinement of the aluminum matrix and the morphology of the Al 3 Sc precipitates depends strongly on the scandium concentration. The tensile properties were evaluated after ECAP by pulling to failure at initial strain rates from 1.0 x 10 -3 to 1.0 x 10 -1 s -1 . The Al-1% Sc alloy exhibited the highest tensile strength of ∼250 MPa at a strain rate of 1.0 x 10 -1 s -1 . This alloy also exhibited a superior grain refinement of ∼0.4 μm after ECAP where this is attributed to a smaller initial grain size and an optimum volume fraction of dispersed Al 3 Sc precipitates having both micrometer and nanometer sizes.

  17. Adsorption and desorption of hydrolyzed metal ions. 3. Scandium and chromium

    International Nuclear Information System (INIS)

    Gray, B.; Matijevic, E.; Clarkson Univ., Potsdam, NY

    1987-01-01

    Adsorption of scandium(III) and chromium(III) species on a PVC latex was measured using radioactive isotopes; the uptake increased with increasing pH. The data were interpreted by combining aspects of the models of James and Healy and also of Anderson and Bockris. The experimental and calculated results agree quite well for scandium, but not for chromium. The deviation in the latter case is believed to be due to polymerization of the hydrolyzed chromium cations and to the interaction of chromium with the anionic surface groups of the latex. Neither of these interactions occur with scandium. Hydrolyzed scandium species adsorbed on the latex were removed by acidifying the dispersion, while chromium complexes were not, substantiating the proposed difference in the chemical nature of chromium and scandium species at the solid/solution interface. 32 refs.; 8 figs.; 8 tabs

  18. A new model for prediction of dispersoid precipitation in aluminium alloys containing zirconium and scandium

    International Nuclear Information System (INIS)

    Robson, J.D.

    2004-01-01

    A model has been developed to predict precipitation of ternary Al 3 (Sc, Zr) dispersoids in aluminium alloys containing zirconium and scandium. The model is based on the classical numerical method of Kampmann and Wagner, extended to predict precipitation of a ternary phase. The model has been applied to the precipitation of dispersoids in scandium containing AA7050. The dispersoid precipitation kinetics and number density are predicted to be sensitive to the scandium concentration, whilst the dispersoid radius is not. The dispersoids are predicted to enrich in zirconium during precipitation. Coarsening has been investigated in detail and it has been predicted that a steady-state size distribution is only reached once coarsening is well advanced. The addition of scandium is predicted to eliminate the dispersoid free zones observed in scandium free 7050, greatly increasing recrystallization resistance

  19. Kinetics and mechanism of hydrolysis of scandium sulfate

    International Nuclear Information System (INIS)

    Koshchej, E.V.; Stryapkov, A.V.; Podosenov, D.E.; Makarov, G.V.; Razdobreev, D.A.

    1998-01-01

    The Sc 2 (SO 4 ) 3 -H 2 SO 4 -H 2 O system is studied through the methods of pH-potentiometry, conductometry and turbidimetry at 298 and 318 K and ion force 0.01, 0.1 and 1.0. The hydrolysis mechanism including the processes in the system homogenous and heterogeneous constituents. The hydrolysis rates of scandium salts and their dependences on OH-ions concentration, solution ions force and temperature are found; the constants of the processes rate with participation of OH - and SO 4 2- ions and constants of the solid phase formation rate are calculated [ru

  20. Vibrational spectra of double oxides of calcium and scandium

    International Nuclear Information System (INIS)

    Porotnikov, N.V.; Kondratov, O.I.; Petrov, K.I.; Olikov, I.I.

    1981-01-01

    The vibrational spectra of calcium and scandium double oxides 40 CaSc 2 O 4 and 44 CaSc 2 O 4 in the range of 30-1000 cm -1 are studied. In the approximation of the polymer chains of the method of valent-force field the calculation of the theoretical vibrational spectrum of isotope-substituted compounds is made, the attribution of the experimental spectra is suggested, the frequency branches of the vibrations of periodic chains are built, the force field of crystals is evaluated [ru

  1. Study on the coextraction of scandium-yttrium-lumogallion complex

    International Nuclear Information System (INIS)

    Okada, T.; Shimoishi, Y.; Miyata, H.; Toei, K.

    1977-01-01

    The coextraction of scandium-yttrium-lumogallion [LMG;4-chloro-6-(2,4-dihydroxyphenylazo)-1-hydroxybenzene-2-sulfonic acid] into diethyl ether has been studied. The acid dissociation constants of LMG, pKsub(a2) and pKsub(a3), were estimated to be 6.24 and 8.05 respectively. The composition of the complex extracted was determined by using the radioisotopes 46 Sc and 90 Y and by spectrophotometry of LMG and the ratio of the components was Sc:Y:LMG = 1:1:3. The coextraction scheme was discussed briefly. (author)

  2. Scandium effect on mechanical properties of Al-6.5 % Mg alloy

    International Nuclear Information System (INIS)

    Drits, M.E.; Toropova, L.S.; Bykov, Yu.G.

    1982-01-01

    Quantitative evaluation of influence of small scandium additions (up to 0.5 wt%) on properties of Al-6.5% Mg binary alloy are carried out depending on test temperature in the range of -196 to 310 deg C. Alloys were tested on ''Instron'' machine at 1.3x10 - 3 s - 1 strain rate. Scandium additions are shown to increase plasticity at -196 deg C. Yield strength also increases with introduction of 0.2% Sc if deformation temperature does not exceed 250 deg C. The growth of ultimate strength is less significant. Elevated strength properties of alloys with scandium additions can be explained by a fine-grained structure

  3. Effect of scandium additions on microstructure and mechanical properties of Al-Zn-Mg alloy welds

    International Nuclear Information System (INIS)

    Dev, Selvi; Stuart, A. Archibald; Kumaar, R.C. Ravi Dev; Murty, B.S.; Rao, K. Prasad

    2007-01-01

    The microstructure and mechanical properties of fusion zones of medium strength Al-Zn-Mg alloy (RDE-40) welds obtained by using different fillers containing various amount of scandium was investigated. It was observed that addition of scandium led to very significant grain refinement in the fusion zone especially for scandium levels greater than the eutectic composition (0.55 wt%). The grain refinement led to the reduction in solidification cracking and improved the tensile properties of fusion zone compared to the ones obtained by the commercial AA5556 filler

  4. Complexonometric photometric titration of scandium in the presence of xylenol orange

    International Nuclear Information System (INIS)

    Kornev, V.I.

    1977-01-01

    Possibility has been studied of using xylenol orange (XO) for chelatometric determination of scandium by means of various chelates with the aid of photometric techniques. It has been established that the chelates applicable for the purpose are ethylenediamineteraacetic acid (EDTA), diethylenediaminetetraacetic acid (DEDTA), diethylenetriaminepentaacetic acid (DETPA), upon introducing of which into a solution containing a complex of scandium with XO (maximum light adsorption at 550 nm) the optical density gradually diminishes. Weakening of the light absorption is, evidently, associated with the destruction of the scandium complex with XO and formation of a colourless chelate acetate with one of the chelates. Chelatometric determination of scandium, using EDTA, DEDTA and DEPTA solutions with XO should be carried out in an acidic medium at pH=2.5-3.0. In this range of pH values interferences caused by the appearance of the Sc-XO complex in the solution are insignificant

  5. Knight shift in scandium and its alloys with hafnium and titanium

    International Nuclear Information System (INIS)

    Chachkhiani, Z.B.; Chechernikov, V.I.; Martynova, L.F.; Nidel'ko, V.I.; Chachkhiani, L.G.; Georgadze, G.S.

    1981-01-01

    Results of the investigation of NMR on 45 Sc nuclei and magnetic susceptibility of scandium and its solid solutions with titanium and hafnium are presented. It is shown that the existing hybridization of S and d zones in pure scandium and its alloys with titanium and hafnium affects the Knight shift reducing the value of the contact contribution. The temperature behaviour of the Knight shift from the temperature dependence and spin susceptibility of collectivized d electrons [ru

  6. Use of scandium ionic associates with salicylic- or 2-phenylquinoline-4-carboxylic acid and rhodamine C

    Energy Technology Data Exchange (ETDEWEB)

    Kononenko, L.I.; Bel' tyukova, S V; Drobyazko, V N; Poluehktov, N S [AN Ukrainskoj SSR, Kiev. Inst. Obshchej i Neorganicheskoj Khimii; AN Ukrainskoj SSR, Odessa. Inst. Obshchej i Neorganicheskoj Khimii)

    1975-09-01

    With salicylic or 2-phenylquinoline-4-carboxylic acid and rhodamine C scandium forms ion associations whose benzene solutions are capable of luminescence. Optimum conditions for the formation of complexes and the composition of the complex with the ratio of Sc:acid:rhodamine C = 1:2:1 are established. A possibility of luminescence determination of scandium in the presence of rare earths is shown.

  7. Analogs of N-cynnamoylphenylhydroxylamine as reagents for amperometric determination of scandium

    International Nuclear Information System (INIS)

    Shvedene, N.V.; Gallaj, Z.A.; Sheina, N.M.; Zujkova, N.V.

    1978-01-01

    To decrease the detection limit of scandium and increase selectivity of amperometric determination, oxidation of 2-furylacryloyl-N-p-chlorophenylhydroxylamine (FACPhHA) and 3-styrylacryloyl-N-phenylhydroxylamine (SAPhHA) on a graphite electrode has been studied by volt-amperometry. The possibility has been established of using the oxidation current of the reagent for plotting the titration curves. The solubility of scandium complexes with FACPhHA and SAPhHA under conditions of titration against the background with pH 6.0 has been determined and equals (2.1+-0.3)x10 -6 and (5.3+-0.3)x10 -7 , respectively. The methods have been developed of amperometric determination of scandium with the use of the considered reagents against backgrounds with pH 5.5-6.5. The use of SAPhHA has decreased the limit of scandium detection down to 0.1 mgk/ml. Besides, the amperometric method makes it possible to titrate in turbid and coloured media what is an advantage of this method. The developed method is used for determination of scandium in scandium silicide

  8. Effect of composition on the superplasticity of aluminium scandium alloys

    International Nuclear Information System (INIS)

    Bradley, E.L. III; Morris, J.W. Jr.

    1992-01-01

    Several aluminum alloys have been shown to exhibit superplasticty in the as-rolled condition. Previous work has shown that aluminum-scandium alloys also exhibit this behavior, but only with the addition of ternary alloying elements such as lithium and magnesium. These additions raised the strain-rate sensitivity of these alloys to 0.4-0.5 for selected strain rates at temperatures above 400 degrees C. A systematic study was undertaken of five Al-Sc alloys with varying lithium and magnesium concentrations in order to fully characterize the high temperature deformation mechanism. Specimens were deformed at a constant strain rate to predetermined true strains for textural and microstructural characterization. In this paper work is presented that will elucidate the effect of these different ternary additives on the superplastic deformation mechanism in these alloys

  9. Application of scandium oxide in an electron emission material

    International Nuclear Information System (INIS)

    Suqiu, Y.; Zhizheng, Z.; Yongde, W.

    1985-01-01

    Modern microwave devices impose a number of harsh requirements on the cathodes. For instance, they require cathodes having low working temperature, high emissive current density, slow evaporation rate of the emissive-active material, long lifetime, quick heating and so on. The commercial B-cathode is no longer able to meet these requirements completely. A scandate cathode may be a promising one for use in these devices. Adding rare-earth elements in the electron emission material has been reported in many papers. Based on a B-cathode we add a little amount of scandium oxide (about 3%) into emission material to manufacture a scandate cathode. The emission property of such a cathode has been improved greatly. If the composition is controlled correctly, the emission level of such a cathode may be five times more as high as the B-cathode

  10. Order-disorder phenomenon in lead scandium tantalate

    International Nuclear Information System (INIS)

    Wang, H.C.; Schulze, W.A.

    1990-01-01

    Lead scandium tatalate (PST) is a ferroelectric relaxor with the perovskite structure of A(B'B double-prime)O 3 . By suitable heat treatment, the B-site cations can be brought from a structurally disordered state into various degree of ordering. The degree of ordering is strongly affected by the amount of vacancies present in the materials. To suppress PbO loss during the sintering or annealing process, a PbO-rich atmosphere is supplied by materials having high PbO vapor pressure, such as PbZrO 3 . For PST ceramics with nearly zero weight loss, very long annealing times and higher annealing temperatures are required for ordering. The higher PbO-loss materials are found to be easily ordered. The introduction of a reducing atmosphere during annealing enhances the ordering process. The ordering process is characterized quantitatively by X-ray diffraction and qualitatively by Raman spectroscopy

  11. Concentration and Separation of Scandium from Ni Laterite Ore Processing Streams

    Directory of Open Access Journals (Sweden)

    Şerif Kaya

    2017-12-01

    Full Text Available The presence of a considerable amount of scandium in lateritic nickel-cobalt ores necessitates the investigation of possible processing alternatives to recover scandium as a byproduct during nickel and cobalt production. Therefore, in this study, rather than interfering with the main nickel-cobalt production circuit, the precipitation-separation behavior of scandium during a pH-controlled precipitation process from a synthetically prepared solution was investigated to adopt the Sc recovery circuit into an already existing hydrometallurgical nickel-cobalt hydroxide processing plant. The composition of the synthetic solution was determined according to the hydrometallurgical nickel laterite ore processing streams obtained from a HPAL (high-pressure sulphuric acid leaching process. In order to selectively precipitate and concentrate scandium with minimum nickel and cobalt co-precipitation, the pH of the solution was adjusted by CaCO3, MgO, Na2CO3, and NaOH. It was found that precipitation with MgO or Na2CO3 is more advantageous to obtain a precipitate containing higher amounts of scandium with minimum mass when compared to the CaCO3 route, which makes further processing more viable. As a result of this study, it is proposed that by a simple pH-controlled precipitation process, scandium can be separated from the nickel and cobalt containing process solutions as a byproduct without affecting the conventional nickel-cobalt hydroxide production. By further processing this scandium-enriched residue by means of leaching, SX (solvent extraction, and precipitation, an intermediate (NH42NaScF6 product can be obtained.

  12. Analysis of separation quality of scandium-46 and titanium using silica gel column

    International Nuclear Information System (INIS)

    Muhamad Basit Febrian; Yanuar Setiadi; Duyeh Setiawan; Titin Sri Mulyati; Nana Suherman

    2015-01-01

    In this study, quality test of scandium and titanium mixture separation system using a silica gel column has been conducted. This system will be used in the separation of medical radioisotopes of 47 Sc from TiO 2 enriched targets. 20 mg of TiO 2 and 5 mg of Sc 2 O 3 dissolved using 0.5 mL of 50% HF solvent with gentle heating at 60°C - 80°C for 1 hour then 4.5 mL H 2 O was added. Sc and Ti mixture is separated by passing it through a column of silica gel. In the determination of scandium released from silica gel, Sc-46 radiotracer was used. Only 51.60 ± 4.5% of 5 mg of scandium could be retained in the silica gel column. From 51.60% of absorbed scandium in the column, 98.29 ± 3.4% were eluted with 5 mL of H 2 O eluent. During elution of scandium from silica gel column, 2.81 grams of 20 mg of titanium came apart as breakthrough. In determination of recovery of titanium from silica gel, 51.76 ± 5.5% of the 20 mg Ti can be recovered from silica gel column using 5M HCl eluent, whereas remaining Ti were eluted using 40 ml of HCl 5M. Based on those result, it can be concluded that there are still titanium portion in scandium after the separation using a silica gel column. Further purification step using fresh silica gel column, can separate escaped titanium from scandium. (author)

  13. Effects of iron on intermetallic compound formation in scandium modified Al–Si–Mg Alloys

    Energy Technology Data Exchange (ETDEWEB)

    Patakham, Ussadawut [National Metal and Materials Technology Center, National Science and Technology Development Agency, 114 Thailand Science Park, Klong Nueng, Klong Luang, Pathumthani 12120 (Thailand); Limmaneevichitr, Chaowalit, E-mail: chaowalit.lim@mail.kmutt.ac.th [Production Engineering Department, Faculty of Engineering, King Mongkut’s University of Technology Thonburi, 126 Pracha-Utid Rd., Bangmod, Tungkhru, Bangkok 10140 (Thailand)

    2014-12-15

    Highlights: • Iron reduces the modification effects of scandium in Al–Si–Mg alloys. • Morphologies of Sc-rich intermetallic phases vary with Fe and Sc contents and the cooling rates. • Sc neutralizes effects of Fe by changing Fe-rich intermetallic phases from platelets to more cubic. - Abstract: In general, iron has a strong tendency to dissolve in molten aluminum. Iron has very low solid solubility in aluminum–silicon casting alloys, so it will form intermetallic compounds that cause detrimental effects on mechanical properties. In this work, the effects of iron on intermetallic compound formations in scandium modified Al–Si–Mg alloys were studied. There were two levels of iron addition (0.2 and 0.4 wt.%) and two levels of scandium addition (0.2 and 0.4 wt.%). We found that the effects of scandium modification decreased with increasing iron addition. The morphologies of the complex intermetallic compounds were characterized by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and electron backscatter diffraction (EBSD) techniques. It was found that scandium changes the morphology of Fe-rich intermetallic compounds from β-phase (plate-like) to α-phase, which reduces the harmful effects of β-phase.

  14. Thermodynamic and kinetic study of scandium(III) complexes of DTPA and DOTA: a step toward scandium radiopharmaceuticals.

    Science.gov (United States)

    Pniok, Miroslav; Kubíček, Vojtěch; Havlíčková, Jana; Kotek, Jan; Sabatie-Gogová, Andrea; Plutnar, Jan; Huclier-Markai, Sandrine; Hermann, Petr

    2014-06-23

    Diethylenetriamine-N,N,N',N'',N''-pentaacetic acid (DTPA) and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) scandium(III) complexes were investigated in the solution and solid state. Three (45)Sc NMR spectroscopic references suitable for aqueous solutions were suggested: 0.1 M Sc(ClO4)3 in 1 M aq. HClO4 (δSc =0.0 ppm), 0.1 M ScCl3 in 1 M aq. HCl (δSc =1.75 ppm) and 0.01 M [Sc(ox)4](5-) (ox(2-) = oxalato) in 1 M aq. K2C2O4 (δSc =8.31 ppm). In solution, [Sc(dtpa)](2-) complex (δSc = 83 ppm, Δν = 770 Hz) has a rather symmetric ligand field unlike highly unsymmetrical donor atom arrangement in [Sc(dota)](-) anion (δSc = 100 ppm, Δν = 4300 Hz). The solid-state structure of K8[Sc2(ox)7]⋅13 H2O contains two [Sc(ox)3](3-) units bridged by twice "side-on" coordinated oxalate anion with Sc(3+) ion in a dodecahedral O8 arrangement. Structures of [Sc(dtpa)](2-) and [Sc(dota)](-) in [(Hguanidine)]2[Sc(dtpa)]⋅3 H2O and K[Sc(dota)][H6 dota]Cl2⋅4 H2O, respectively, are analogous to those of trivalent lanthanide complexes with the same ligands. The [Sc(dota)](-) unit exhibits twisted square-antiprismatic arrangement without an axial ligand (TSA' isomer) and [Sc(dota)](-) and (H6 dota)(2+) units are bridged by a K(+) cation. A surprisingly high value of the last DOTA dissociation constant (pKa =12.9) was determined by potentiometry and confirmed by using NMR spectroscopy. Stability constants of scandium(III) complexes (log KScL 27.43 and 30.79 for DTPA and DOTA, respectively) were determined from potentiometric and (45)Sc NMR spectroscopic data. Both complexes are fully formed even below pH 2. Complexation of DOTA with the Sc(3+) ion is much faster than with trivalent lanthanides. Proton-assisted decomplexation of the [Sc(dota)](-) complex (τ1/2 =45 h; 1 M aq. HCl, 25 °C) is much slower than that for [Ln(dota)](-) complexes. Therefore, DOTA and its derivatives seem to be very suitable ligands for scandium

  15. Double tungstates of metals of scandium and ammonium subgroups

    Energy Technology Data Exchange (ETDEWEB)

    Maksin, V I [AN Ukrainskoj SSR, Kiev. Inst. Kolloidnoj Khimii i Khimii Vody

    1980-06-01

    The methods of pH-potentiometry, conductometry, determination of residual concentrations of liquid phases and precipitations, selected by chemical analysis have been used for investigation R(NO/sub 3/)/sub 3/-(NH/sub 4/)/sub 2/WO/sub 2/-H/sub 2/O systems, (where R=Sc, Y, La). The formation of double tungstates NH/sub 4/R(WO/sub 4/)/sub 2/xnH/sub 2/O is established. The NH/sub 4/Sc(WO/sub 4/)/sub 2/x4.5H/sub 2/O, NH/sub 4/Yx(WO/sub 4/)/sub 2/x3H/sub 2/O, NH/sub 4/La(WO/sub 4/)/sub 2/x1.5H/sub 2/O compounds are synthesized in individual form. Precipitation conditions (pH, concentration ratio) and composition of the solid phase are determined. The behaviour of synthesized slats at thermolysis up to 880 deg C is studied. Physicochemical properties (color, solubility of the simple and double tungstates of scandium, yttrium and lanthanum with ammonium) is studied. IR spectra and X-ray diffraction analysis give idea about double salts structural transformations.

  16. Hydrogen storage in thin film magnesium-scandium alloys

    International Nuclear Information System (INIS)

    Niessen, R.A. H.; Notten, P.H. L.

    2005-01-01

    Thorough electrochemical materials research has been performed on thin films of novel magnesium-scandium hydrogen storage alloys. It was found that palladium-capped thin films of Mg x Sc (1-x) with different compositions (ranging from x=0.50 -0.90) show an increase in hydrogen storage capacity of more than 5-20% as compared to their bulk equivalents using even higher discharge rates. The maximum reversible hydrogen storage capacity at the optimal composition (Mg 80 Sc 20 ) amounts to 1795-bar mAh/g corresponding to a hydrogen content of 2.05 H/M or 6.7-bar wt.%, which is close to five times that of the commonly used hydride-forming materials in commercial NiMH batteries. Galvanostatic intermittent titration technique (GITT) measurements show that the equilibrium pressure during discharge is lower than that of bulk powders by one order of magnitude (10 -7 -bar mbar versus 10 -6 -bar mbar, respectively)

  17. The spectrum of four times ionized scandium, Sc V

    International Nuclear Information System (INIS)

    Smitt, R.; Ekberg, J.O.

    1985-01-01

    The spectrum of four times ionized scandium emitted from a sliding spark discharge has been observed using a 3 m normal incidence spectrograph and a 5 m grazing incidence spectrograph. About 450 lines in the wavelength region 160 A to 220 A have been identified as combinations between 46 odd levels belonging to the 3s 2 3p 5 , 3s 2 3p 4 4p and 3s3p 5 3d configurations and 72 even levels of the 3s3p 6 , 3s 2 3p 4 3d, 4d, 4s and 5s configurations. Of the previous identifications we have confirmed 18 levels. The level structure of the observed configurations has been theoretically interpreted by including configuration interaction effects. The inclusion of 3s 2 3p 3 3d 2 in the calculations of the odd parity configurations is found to be important. Almost all levels of 3s3p 5 3d show a considerable mixing with levels of 3s 2 3p 3 3d 2 , in some cases by as much as 50%. The energy parameters determined from least-squares fits to the observed level values are compared with Hartree-Fock calculations. The ionization energy is estimated to be 739 500 +- 1000 cm -1 . (91.65 +- 0,12 eV). (orig.)

  18. Aluminum-Scandium: A Material for Semiconductor Packaging

    Science.gov (United States)

    Geissler, Ute; Thomas, Sven; Schneider-Ramelow, Martin; Mukhopadhyay, Biswajit; Lang, Klaus-Dieter

    2016-10-01

    A well-known aluminum-scandium (Al-Sc) alloy, already used in lightweight sports equipment, is about to be established for use in electronic packaging. One application for Al-Sc alloy is manufacture of bonding wires. The special feature of the alloy is its ability to harden by precipitation. The new bonding wires with electrical conductivity similar to pure Al wires can be processed on common wire bonders for aluminum wedge/wedge (w/w) bonding. The wires exhibit very fine-grained microstructure. Small Al3Sc particles are the main reason for its high strength and prevent recrystallization and grain growth at higher temperatures (>150°C). After the wire-bonding process, the interface is well closed. Reliability investigations by active power cycling demonstrated considerably improved lifetime compared with pure Al heavy wires. Furthermore, the Al-Sc alloy was sputter-deposited onto silicon wafer to test it as chip metallization in copper (Cu) ball/wedge bonding technology. After deposition, the layers exhibited fine-grained columnar structure and small coherent Al3Sc particles with dimensions of a few nanometers. These particles inhibit softening processes such as Al splashing in fine wire bonding processes and increase the thickness of remnant Al under the copper balls to 85% of the initial thickness.

  19. Thermomechanical treatment of welded joints of aluminum-lithium alloys modified by scandium

    Science.gov (United States)

    Malikov, A. G.

    2017-12-01

    At present, the aeronautical equipment manufacture involves up-to-date high-strength aluminum alloys of decreased density resulting from the lithium admixture. Various technologies of fusible welding of these alloys are being developed. The paper presents experimental investigations of the optimization of the laser welding of aluminum alloys with the scandium-modified welded joint after thermomechanical treatment. The effect of scandium on the micro- and macrostructure is studied along with strength characteristics of the welded joint. It is found that thermomechanical treatment allows us to obtain the strength of the welded joint 0.89 for the Al-Mg-Li system and 0.99 for the Al-Cu-Li system with the welded joint modified by scandium in comparison with the base alloy after treatment.

  20. The enthalpy of solid scandium in the temperature range 406 - 1812 K

    International Nuclear Information System (INIS)

    Lyapunov, K.M.; Baginskij, A.V.; Stankus, S.V.

    2001-01-01

    Enthalpy of pure scandium was measured on massive calorimeter in the range from 406 to 1812 K by mixing method. The enthalpy of face centered close cubic lattice - body centered cubic lattice transformation is equal to ΔH t 4068 J/mol. Obtained value within the limits of error is compatible with the results given earlier (4009 J/mol). The dependence of the middle specific heat of scandium C p (T) on the temperature was shown in correlation with the results of other works. The results of the conducted experiments reinforce the conclusion made earlier about an absence (or a little) in the decomposition of an anharmonic component of the oscillation specific heat of scandium C p a (T) members proportional to the first or the second degrees of temperature [ru

  1. Biamperometric analysis of nonaqueous scandium solutions containing lanthanides, lead and thorium

    International Nuclear Information System (INIS)

    Gevorgyan, A.M.; Talipov, Sh.T.; Kostylev, V.S.; Khadeev, V.A.; Nadol'skij, M.Ya.

    1978-01-01

    Investigated was a possibility of direct scandium titration in the presence of large rare earth quantities, and also a possibility of complexonometric scandium and rare earth sum determination at their joint presence in non-aqueous acetic acid solution. The titration was carried out at electrode voltage of 0.95V, background electrolyte concentration of lithium perchlorate being 0.2M. Non-aqueous magnesium complexonate was used as titrating reagent. Th and Pb complexonates are shown to be less stable as compared to Sc complexonate, and consequently, Th and Pb ions must not interfere with biamperometric titration of Sc ion. A method applied to analysis of binary mixture, containing scandium, and a method for model alloy and thortveitite mineral was developed. Well reproducible and precise enough results are obtained in all the cases. Ions of Bi, Cu, Cd, Zn, In, Ga and Ti interfere with determination

  2. Pressure-induced structural change from hexagonal to fcc metal lattice in scandium trihydride

    International Nuclear Information System (INIS)

    Ohmura, A.; Machida, A.; Watanuki, T.; Aoki, K.; Nakano, S.; Takemura, K.

    2007-01-01

    We synthesized scandium hydrides by hydrogenation of a scandium foil with hydrogen fluid under high pressure at ambient temperature. Scandium dihydride (ScH 2 ) and trihydride (ScH 3 ) were prepared near 4 and 5 GPa, respectively. The hydrogenation process and pressure-induced structural changes in ScH 3 were investigated by synchrotron radiation X-ray diffraction measurements up to 54.7 GPa. A structural transition from hexagonal to the fcc lattice began at 30 GPa and was completed at 46 GPa via an intermediate state similar to those reported for other hexagonal trihydrides. The intermediate state was not interpreted in terms of a coexisting state for the low-pressure hexagonal and the high-pressure fcc structures. The onset transition pressure of ScH 3 supported the previously proposed relation that the hexagonal-fcc transition pressure is inversely proportional to the ionic radius of the trihydride

  3. Scandium complexes with the tetraphenylethylene and anthracene dianions.

    Science.gov (United States)

    Ellis, John E; Minyaev, Mikhail E; Nifant'ev, Ilya E; Churakov, Andrei V

    2018-06-01

    The structural study of Sc complexes containing dianions of anthracene and tetraphenylethylene should shed some light on the nature of rare-earth metal-carbon bonding. The crystal structures of (18-crown-6)bis(tetrahydrofuran-κO)sodium bis(η 6 -1,1,2,2-tetraphenylethenediyl)scandium(III) tetrahydrofuran disolvate, [Na(C 4 H 8 O) 2 (C 12 H 24 O 6 )][Sc(C 26 H 20 ) 2 ]·2C 4 H 8 O or [Na(18-crown-6)(THF) 2 ][Sc(η 6 -C 2 Ph 4 ) 2 ]·2(THF), (1b), (η 5 -1,3-diphenylcyclopentadienyl)(tetrahydrofuran-κO)(η 6 -1,1,2,2-tetraphenylethenediyl)scandium(III) toluene hemisolvate, [Sc(C 17 H 13 )(C 26 H 20 )(C 4 H 8 O)]·0.5C 7 H 8 or [(η 5 -1,3-Ph 2 C 5 H 3 )Sc(η 6 -C 2 Ph 4 )(THF)]·0.5(toluene), (5b), poly[[(μ 2 -η 3 :η 3 -anthracenediyl)bis(η 6 -anthracenediyl)bis(η 5 -1,3-diphenylcyclopentadienyl)tetrakis(tetrahydrofuran)dipotassiumdiscandium(III)] tetrahydrofuran monosolvate], {[K 2 Sc 2 (C 14 H 10 ) 3 (C 17 H 13 ) 2 (C 4 H 8 O) 4 ]·C 4 H 8 O} n or [K(THF) 2 ] 2 [(1,3-Ph 2 C 5 H 3 ) 2 Sc 2 (C 14 H 10 ) 3 ]·THF, (6), and 1,4-diphenylcyclopenta-1,3-diene, C 17 H 14 , (3a), have been established. The [Sc(η 6 -C 2 Ph 4 ) 2 ] - complex anion in (1b) contains the tetraphenylethylene dianion in a symmetrical bis-η 3 -allyl coordination mode. The complex homoleptic [Sc(η 6 -C 2 Ph 4 ) 2 ] - anion retains its structure in THF solution, displaying hindered rotation of the coordinated phenyl rings. The 1D 1 H and 13 C{ 1 H}, and 2D COSY 1 H- 1 H and 13 C- 1 H NMR data are presented for M[Sc(Ph 4 C 2 ) 2 ]·xTHF [M = Na and x = 4 for (1a); M = K and x = 3.5 for (2a)] in THF-d 8 media. Complex (5b) exhibits an unsymmetrical bis-η 3 -allyl coordination mode of the dianion, but this changes to a η 4 coordination mode for (1,3-Ph 2 C 5 H 3 )Sc(Ph 4 C 2 )(THF) 2 , (5a), in THF-d 8 solution. A 45 Sc NMR study of (2a) and UV-Vis studies of (1a), (2a) and (5a) indicate a significant covalent contribution to the Sc-Ph 4 C 2 bond character. The unique Sc ate complex, (6

  4. Bonding in scandium monosulfide a NaCl crystal type

    International Nuclear Information System (INIS)

    Merrick, J.A.

    1980-08-01

    The transition temperature of an order-disorder transition in Sc 0 81 S (R anti 3m to Fm3m) occurs at 700 0 C. A group of ordered sublattices on the NaCl-type lattice (Fm3m) was generated and a Madelung energy and configurational entropy were calculated for each sublattice assuming the ions to be Sc 2 48+ and S 2- . Mean field and pair interaction approximations were used to model long-range and short-range orderings, respectively. The electrostatic model fails to predict the observed short-range and long-range orderings. The high temperature vaporization of ScP was investigated by mass spectrometry and target collection Knudsen effusion at 1767 to 2209K. The composition ScP 1 00 vaporizes congruently to the gaseous species Sc, P, and P 2 . A temperature independent third law enthalpy of atomization (ΔH 0 /sub atom,298/ = 252.2 +- 2.8 kcal mole -1 ) has a value approx. 12 kcal larger than that reported for ScS. Nonrelativistic, nonself-consistent LAPW band structure calculations are reported for ScS. XPS and UPS measurements are reported for Sc 2 S 3 and several compositions Sc/sub 1-x/S (0.0 less than or equal to x less than or equal to 0.2). The Sc and S 2p binding energies (XPS) obtained for the defect scandium monosulfides are very close to those found in the pure elements, suggesting covalent bonding. The Sc 2p energy region has an interesting satellite structure

  5. The effects of aluminum or scandium on the toughness, density and ...

    African Journals Online (AJOL)

    The effects of the substitution of aluminum or scandium on the density, toughness as well as the stability of the phases formed by such an addition on platinum, iridium, rhodium and palladium metals were evaluated with the density functional quantum mechanical calculation methods. All the metals had four atoms per ...

  6. Study of competitive complexing in scandium(3)-xylenol-orange-hydroxyethyliminodiacetic acid system

    International Nuclear Information System (INIS)

    Kornev, V.I.; Mukanov, I.P.; Artem'eva, O.A.

    1976-01-01

    The competitive complexing in the system scandium(3)-xylene orange (XO)-hydroxyethyliminodiacetic acid (H 3 L) has been studied. Ligands act as competitive particles. It has been established preliminarily that introduction of H 3 L into the solution containing a mixture of Sc and Xo changes considerably the absorption spectra of the coloured complex. Weakening of light absorption indicates that the coloured complex with XO is destructed and colourless hydroxyethyliminodiacetate of scandium is formed. The formation of scandium hydroxyethyliminoacetate has been studied spectrophotometrically by equilibrium between the complexes. The dependence of optical density on pH, when the concentrations of reagents are constant, as well as on concetration of H 3 L has been studied. The composition of the complex (1:1) formed at pH 3.2 has been established graphically and the constant of the complex ScHL + instability has been calculated (PKsub(H)=10.69+-0.45). It has been shown that H 3 L, when interacting with scandium, behaves as dibasic ligand. It is most probable that during complex formation the hydrogen ion of the hydroxygroup is not replaced, although the participation of hydroxygroup in coordination is possible due to a donor-acceptor bond

  7. Structural differences of half-sandwich complexes of scandium and yttrium containing bulky substituents

    Czech Academy of Sciences Publication Activity Database

    Fridrichová, Adéla; Růžička, A.; Lamač, Martin; Horáček, Michal

    2017-01-01

    Roč. 76, FEB 2017 (2017), s. 62-66 ISSN 1387-7003 R&D Projects: GA ČR(CZ) GAP207/12/2368 Institutional support: RVO:61388955 Keywords : scandium * yttrium * half-sandwich Subject RIV: CF - Physical ; Theoretical Chemistry OBOR OECD: Physical chemistry Impact factor: 1.640, year: 2016

  8. In situ observation of the reaction of scandium and carbon by neutron diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Juarez-Arellano, Erick A., E-mail: eajuarez@unpa.edu.m [Institut fuer Geowissenschaften, Universitaet Frankfurt, Altenhoeferallee 1, 60438 Frankfurt a.M. (Germany); Universidad del Papaloapan, Circuito Central 200, Parque Industrial, Tuxtepec 68301 (Mexico); Winkler, Bjorn [Institut fuer Geowissenschaften, Universitaet Frankfurt, Altenhoeferallee 1, 60438 Frankfurt a.M. (Germany); Vogel, Sven C. [Los Alamos National Laboratory, Lujan Center. Mail Stop H805, Los Alamos, NM 87545 (United States); Senyshyn, Anatoliy [Forschungsneutronenquelle Heinz Maier-Leibnitz (FRM II), Technische Universitaet Muenchen, Lichtenbergstr. 1, D-85747 Garching (Germany); Materialwissenschaft, TU Darmstadt, Petersensstr. 23, D-64287 Darmstadt (Germany); Kammler, Daniel R. [Sandia National Laboratories, Albuquerque, NM 87185 (United States); Avalos-Borja, Miguel [CNyN, UNAM, A. Postal 2681, Ensenada, B.C. (Mexico)

    2011-01-05

    Research highlights: {yields} Exist two ScC cubic phases with B1-structure type differing in site occupancy of C. {yields} A new orthorhombic scandium carbide phase is formed at 1473(50) K. {yields} The recrystallization of alpha-Sc occurs between 1000 and 1223 K. - Abstract: The formation of scandium carbides by reaction of the elements has been investigated by in situ neutron diffraction up to 1823 K. On heating, the recrystallization of {alpha}-Sc occurs between 1000 and 1223 K. The formation of Sc{sub 2}C and ScC (NaCl-B1 type structure) phases has been detected at 1323 and 1373 K, respectively. The formation of a new orthorhombic scandium carbide phase was observed at 1473(50) K. Once the scandium carbides are formed they are stable upon heating or cooling. No other phases were detected in the present study, in which the system was always carbon saturated. The thermal expansion coefficients of all phases have been determined, they are constant throughout the temperature interval studied.

  9. Process Design Aspects for Scandium-Selective Leaching of Bauxite Residue with Sulfuric Acid

    OpenAIRE

    Konstantinos Hatzilyberis; Theopisti Lymperopoulou; Lamprini-Areti Tsakanika; Klaus-Michael Ochsenkühn; Paraskevas Georgiou; Nikolaos Defteraios; Fotios Tsopelas; Maria Ochsenkühn-Petropoulou

    2018-01-01

    Aiming at the industrial scale development of a Scandium (Sc)-selective leaching process of Bauxite Residue (BR), a set of process design aspects has been investigated. The interpretation of experimental data for Sc leaching yield, with sulfuric acid as the leaching solvent, has shown significant impact from acid feed concentration, mixing time, liquid to solids ratio (L/S), and number of cycles of leachate re-usage onto fresh BR. The thin film diffusion model, as the fundamental theory for l...

  10. Diagrammatic Representation of Electronic Correlations in Photoionization Process: Application to Scandium

    International Nuclear Information System (INIS)

    Liu Mengmeng; Ma Xiaoguang

    2011-01-01

    The conversion rules under which an algebraic expression can be obtained from a corresponding photoionization Goldstone diagram have been given systematically in the present work. The electronic correlations in the photoionization processes then could be studied diagrammatically. The application to atomic scandium shows that the present theoretical scheme can give reasonable photoionization cross sections, which agree well with the experimental results. (atomic and molecular physics)

  11. Pilot-scale recovery of rare earths and scandium from phosphogypsum and uranium leachates

    Directory of Open Access Journals (Sweden)

    Mashkovtsev Maxim

    2016-01-01

    Full Text Available Ural Federal University (UrFU and VTT have performed joint research on development of industrial technologies for the extraction of REM and Scandium compounds from phosphogypsum and Uranium ISL leachate solutions. Leaching-absorption experiments at UrFU have been supported with multicomponent solution modelling by VTT. The simulations have been performed with VTT’s ChemSheet/Balas program and can be used for speciation calculations in the lixiviant solution. The experimental work combines solvent extraction with advanced ion exchange methodology in a pilot facility capable of treating 5 m3 solution per hour. Currently, the plant produces cerium carbonate, lanthanum oxide, neodymium oxide and concentrate of heavy rare earth metals. A batch of 45 t solids has been processed with the gain of 100 kg’s of REM concentrate. A mini-pilot plant with productivity above 50 liters per hour has been applied to recover scandium oxide and REE concentrates from the uranium ISL solution. As the preliminary product contains radioactivity (mainly strontium, an additional decontamination and cleaning of both concentrates by extraction has rendered a necessity. Finally a purified 99% concentrate of scandium oxide as well as 99% rare earth concentrate are received.

  12. Effect of scandium on the phase composition and mechanical properties of ABM alloys

    Science.gov (United States)

    Molchanova, L. V.

    2010-09-01

    The effect of scandium on the composition and mechanical properties of ABM-1 alloys (Al-30% Be-5% Mg) is studied. The scandium content is varied from 0.1 to 0.5 wt %. It is established that, in the studied part of the Al-Be-Mg-Sc system, an aluminum solid solution (Al) and the ScBe13 compound are in equilibrium with a beryllium solid solution (Be). Magnesium dissolves in both the aluminum component and the ScBe13 compound. The strengthening effect related to the decomposition of the solid solution and the precipitation of Al3Sc cannot be extended to the strengthening of ABM-type alloys. Additions of 0.1-0.15 wt % Sc only weakly improve the mechanical properties of the alloys due to the refinement of beryllium-component grains. At high scandium contents, the strength increases insignificantly due to primary precipitation of ScBe13 and the plasticity decreases simultaneously.

  13. Influence of scandium on the pitting behaviour of Al-Zn-Mg-Cu alloys

    Energy Technology Data Exchange (ETDEWEB)

    Wloka, J. [Department of Materials Sciences, University of Erlangen-Nuremberg, Martensstrasse 7, D-91058 Erlangen (Germany); Virtanen, S. [Department of Materials Sciences, University of Erlangen-Nuremberg, Martensstrasse 7, D-91058 Erlangen (Germany)], E-mail: virtanen@ww.uni-erlangen.de

    2007-11-15

    In this paper the influence of small scandium additions (<0.26 wt.%) on the corrosion properties of the high-strength Al-Zn-Mg-Cu alloy AA7010 is investigated. The addition of scandium (in combination with the grain refiner Zr) leads to the formation of Al{sub 3}Sc{sub x}Zr{sub 1-x} phases. These coarse particles disturb the grain structure near the particle/matrix interface, which facilitates the initiation of localized corrosion in potentio-dynamic scans. Microelectrochemical investigations revealed a slightly cathodic character of these particles and a passive range beyond the breakdown potential of the matrix. Mass loss measurements show that the addition of scandium increases the mass loss during the initial period. The corrosion morphology was investigated with optical and scanning electron microscopy. The composition of the phases was determined with energy-dispersive X-ray analysis. Micro-capillary measurements were performed to investigate the electrochemical properties of single phases surrounded by matrix.

  14. Solvent extraction of tricomponent complexes of zirconium and scandium with salicylic acid and collidine

    International Nuclear Information System (INIS)

    Kochetkova, S.K.; Fadeeva, V.I.; Kalistratova, V.P.

    1976-01-01

    Extraction of tricomponent compounds of zirconium and scandium with salicylic acid (Sal) and collidine (Col) has been studied. Addition of Col widens considerably the pH range of maximum extraction of zirconium salicylate and makes it possible to extract quantitatively both zirconium and scandium in the following pH range: scandium at pH 3.8-5.2; zirconium at pH 2-4. Optimum concentrations of salicylic acid and collidine are 0.05 mol/l and 0.375 mol/l, respectively. The composition of the complexes being extracted has been studied by the shift equilibrium method. Chloroform extracts complexes having the ratio Zr:Sal:Col=1:2:1(pH=3); Sc:Sal:Col=1:3:1(pH=4), and 1:2:1(pH=5). The composition of the complexes being formed is assumed to be [Zr(OH) 3 (HSal) 2 ] - [ColH + ] (pH=3); Sc(HSal) 3 xCol (pH=4.0); Sc(OH)(HSal) 2 xCol (pH=5.0). Extraction of collidine-salicylate complexes of Hf, Th, La, and Y under the conditions of optimum extraction of zirconium and scandium has been investigated when concentration of Zr and Sc in the solution is 3.0.10μ- 5 -1.37.10 -4 mol/l, respectively. It has been shown that hafnium is extracted quantitatively (95-100%) at pH 2.3-4.6; thorium at pH 3.0-6.4; 60% of yttrium is extracted at pH 4.0-4.8; 25% of lanthanum is extracted at pH 3.3-4.9. At pH 2.0 it is possible to separate Zr from Sc,Y, and La; at pH 1.4-1.5 from small amounts of Hf and Tn. Separation of zirconium, from small amounts of hafnium, 10-fold amounts of thorium, 100-fold amounts of scandium and lanthanum is also possible

  15. Solvent extraction of tricomponent complexes of zirconium and scandium with salicylic acid and collidine

    Energy Technology Data Exchange (ETDEWEB)

    Kochetkova, S K; Fadeeva, V I; Kalistratova, V P [Moskovskij Gosudarstvennyj Univ. (USSR)

    1976-01-01

    Extraction of tricomponent compounds of zirconium and scandium with salicylic acid (Sal) and collidine (Col) has been studied. Addition of Col widens considerably the pH range of maximum extraction of zirconium salicylate and makes it possible to extract quantitatively both zirconium and scandium in the following pH range: scandium at pH 3.8-5.2; zirconium at pH 2-4. Optimum concentrations of salicylic acid and collidine are 0.05 mol/l and 0.375 mol/l, respectively. The composition of the complexes being extracted has been studied by the shift equilibrium method. Chloroform extracts complexes having the ratio Zr:Sal:Col=1:2:1(pH=3); Sc:Sal:Col=1:3:1(pH=4), and 1:2:1(pH=5). The composition of the complexes being formed is assumed to be (Zr(OH)/sub 3/(HSal)/sub 2/)/sup -/(ColH/sup +/) (pH=3); Sc(HSal)/sub 3/xCol (pH=4.0); Sc(OH)(HSal)/sub 2/xCol (pH=5.0). Extraction of collidine-salicylate complexes of Hf, Th, La, and Y under the conditions of optimum extraction of zirconium and scandium has been investigated when concentration of Zr and Sc in the solution is 3.0.10..mu..-/sup 5/-1.37.10/sup -4/ mol/l, respectively. It has been shown that hafnium is extracted quantitatively (95-100%) at pH 2.3-4.6; thorium at pH 3.0-6.4; 60% of yttrium is extracted at pH 4.0-4.8; 25% of lanthanum is extracted at pH 3.3-4.9. At pH 2.0 it is possible to separate Zr from Sc,Y, and La; at pH 1.4-1.5 from small amounts of Hf and Tn. Separation of zirconium, from small amounts of hafnium, 10-fold amounts of thorium, 100-fold amounts of scandium and lanthanum is also possible.

  16. Hardening mechanisms of spray formed Al-Zn-Mg-Cu alloys with scandium and other elemental additions

    International Nuclear Information System (INIS)

    Sharma, M.M.; Amateau, M.F.; Eden, T.J.

    2006-01-01

    The hardening mechanisms in spray formed Al-Zn-Mg-Cu alloys with additions of chromium, zinc and scandium were studied. The microstructure of the spray formed alloys was analyzed by transmission electron microscopy. A range of tensile strengths were achieved, and varied based on elemental additions, and second phase particle strengthening. To explain the significantly higher strength in one alloy with scandium, theoretical results due to the yield stress of Al-Zn-Mg-Cu alloys as a function of volume fraction and precipitate particle size, were compared to experimental data. Both the possibilities of coherency and order strengthening are examined. The significant additional hardening achieved in the alloy with scandium is attributed to small ordered particles of Al 3 Sc, which precipitated during aging

  17. Potential for photocatalytic degradation of the potassic diclofenac using scandium and silver modified titanium dioxide thin films

    International Nuclear Information System (INIS)

    Ciola, R.A.; Oliveira, C.T.; Lopes, S.A.; Cavalheiro, A.A.

    2011-01-01

    The potential for photocatalytic degradation of the potassic diclofenac drug was investigated using titanium dioxide thin films modified with two modifier types, scandium and silver, both prepared by Sol-Gel method. It was demonstrated by UVVis spectroscopy analysis of the solutions containing the drug, under UV-A light irradiation that the degradation efficiency of the titanium dioxide photocatalyst is dependent of the semiconductor nature and that the scandium accelerates the first step of the degradation when compared to the silver. This result seems to be related to the redox potential of the electron-hole pair, once the scandium modifying sample generates a p type semiconductor that reduces the band gap. The extra holes attract more strongly the chorine ion present in diclofenac and leading to the releasing more easily. However, after the first byproducts degradation the following steps are not facilitated, making the silver modifying more advantageous. (author)

  18. The influence of the diluent nature on scandium extraction by the phenol-formaldehyde resol oligomer yarrezin B

    International Nuclear Information System (INIS)

    Semenov, S.A.; Valkina, E.M.; Reznik, A.M.

    1996-01-01

    The paper studies the effect of diluent nature on scandium extraction by Yarrezin B phenol-formaldehyde resol oligomer using n-octan, toluene, chloroform, n-octanol and kerosene as an example. Correlation coefficients of dependences of scandium distribution factor on some parameters of diluents are calculated. Possibility to use some parameters of diluents to predict their effect on extraction indices is determined. Hildebrandt solubility parameter of extracting agent and parameters of extracting agent-diluent interaction according to Flory-Haggins are calculated. 13 refs., 2 figs., 4 tabs

  19. Determination of aluminium, scandium and rare earth elements by emission flame spectrometry

    International Nuclear Information System (INIS)

    Otruba, V.; Sommer, L.

    1989-01-01

    Emission spectrometry in nitrous oxide-acetylene flames in combination with a highly resolving double monochromator and sensitive detecting system enables simple, sensitive and selective determinations of aluminium, scandium and all rare earth elements with exception of cerium in complicated matrices. Calibration plots are linear for a large concentration interval (≤ 100 μgxml -1 ), detection limits are in ngxml -1 level and RSD does not exceed 3% on the optimal concentration level of the particular element. The determination of Al, Sc, Eu and Yb showed particular advantages as to methods using ICP-spectrometry. (orig.)

  20. 3He release characteristics of metal tritides and scandium--tritium solid solutions

    International Nuclear Information System (INIS)

    Perkins, W.G.; Kass, W.J.; Beavis, L.C.

    1975-01-01

    Tritides of such metals as scandium, titanium, and erbium are useful materials for determining the effects of helium accumulation in metallic solids, for example, CTR first wall materials. Such effects include lattice strain and gross deformation, as reported elsewhere, which are related to 3 He retention and ultimate release. Long term gas release studies have indicated that, during the early life of a metal ditritide, a large fraction of the 3 He is retained in the solid. At more advanced ages (2 to 4 years, depending on the parent metal), the 3 He release rate becomes comparable to the generation rate. Statistical analysis of the data indicates that the acceleration in 3 He release rate depends on accumulated 3 He concentration rather than strictly on age. 3 He outgassing results are presented for thin films of ScT 2 , TiT 2 , and ErT 2 , and the critical 3 He concentrations are discussed in terms of a percolation model. Phase transformations which occur on tritide formation cast some doubt on the validity of extrapolating results obtained for metal tritides to predictions regarding the accumulation of helium in metals. Scandium is unique among the early transition and rare-earth metals in that the metal exhibits a very high room temperature tritium solubility (T/Sc = 0.4) with no phase transformation. Indeed, even the lattice parameters of the hcp scandium lattice are only minimally changed by tritium solution, and we have succeeded in obtaining single crystal ScT 0 . 3 samples in two crystallographic orientations. Using a very sensitive technique, we have measured 3 He emission from both these samples, as well as from fine-grained thin film scandium-tritium solid solution samples (ScT 0 . 3 - 0 . 4 ). The fine-grained film samples release 3 He at 2 to 3 percent of the generation rate, while the emission rate from the single-crystal samples is approximately 0.05 percent of the generation rate, indicating a strong grain size effect

  1. Scandium-doped zinc cadmium oxide as a new stable n-type oxide thermoelectric material

    DEFF Research Database (Denmark)

    Han, Li; Christensen, Dennis Valbjørn; Bhowmik, Arghya

    2016-01-01

    Scandium-doped zinc cadmium oxide (Sc-doped ZnCdO) is proposed as a new n-type oxide thermoelectric material. The material is sintered in air to maintain the oxygen stoichiometry and avoid instability issues. The successful alloying of CdO with ZnO at a molar ratio of 1 : 9 significantly reduced...... is a good candidate for improving the overall conversion efficiencies in oxide thermoelectric modules. Meanwhile, Sc-doped ZnCdO is robust in air at high temperatures, whereas other n-type materials, such as Al-doped ZnO, will experience rapid degradation of their electrical conductivity and ZT....

  2. Scandium sorption by immobilized microdispersed forms of phosporus-containing ion exchangers

    International Nuclear Information System (INIS)

    Sokolova, Yu.V.; Kurdyumov, G.M.; Smirnov, A.V.; Mezhirov, M.S.

    1991-01-01

    The possibility to improve considerably kinetics of scandium sorption by phosphate ion exchangers, immobilized into polyacrylonitrile (PAN) fibers, as compared with granular samples of ion exchangers, was shown. The influence of dispersion degree of immobilized ionite particles on sorption rate was studied. It is ascertained that the ionite grinding to the particle size ≤ 52 μm is sufficient for the rate increase by 1-1.5 orders. A lower swelling of the immobilized ion exchanger is its additional advantage as compared with granular form

  3. Why does the lumen maintenance of sodium-scandium metal halide lamps improve by VHF operation?

    International Nuclear Information System (INIS)

    Van Erk, W; Luijks, G M J F; Hitchcock, W

    2011-01-01

    Lifetime experiments show that sodium-scandium metal halide lamps perform better on very high frequency (VHF) drivers than on low frequency (LF) constant wattage autotransformer (CWA) ballasts. The question why, will be addressed with focus on arc tube aspects. It is argued that at high frequency operation sodium loss is less, and that the absence of thermal fluctuations in the electrode tip causes less damage and cracking to this part of the electrode. Sudden lm W -1 drops, observed with CWA-operated lamps, most probably occur when the arc attaches on such a corroded and cracked surface. Thorium is effective as an emitter both in the CWA and the VHF operation mode, despite the absence of cataphoretic transport to the cathode in the VHF case.

  4. Why does the lumen maintenance of sodium-scandium metal halide lamps improve by VHF operation?

    Energy Technology Data Exchange (ETDEWEB)

    Van Erk, W [Philips Lighting, Sondervick 47, 5505 NB Veldhoven (Netherlands); Luijks, G M J F [Advanced Development Lighting, Philips Lighting, PO Box 80020, 5600 JM Eindhoven (Netherlands); Hitchcock, W, E-mail: Gerard.luijks@philips.com [Philips Lighting Company, 7265 Route 54, Bath, NY 14810 (United States)

    2011-06-08

    Lifetime experiments show that sodium-scandium metal halide lamps perform better on very high frequency (VHF) drivers than on low frequency (LF) constant wattage autotransformer (CWA) ballasts. The question why, will be addressed with focus on arc tube aspects. It is argued that at high frequency operation sodium loss is less, and that the absence of thermal fluctuations in the electrode tip causes less damage and cracking to this part of the electrode. Sudden lm W{sup -1} drops, observed with CWA-operated lamps, most probably occur when the arc attaches on such a corroded and cracked surface. Thorium is effective as an emitter both in the CWA and the VHF operation mode, despite the absence of cataphoretic transport to the cathode in the VHF case.

  5. Influence of scandium on the microstructure and mechanical properties of A319 alloy

    International Nuclear Information System (INIS)

    Emadi, Daryoush; Rao, A.K. Prasada; Mahfoud, Musbah

    2010-01-01

    Recycling of aluminum scrap alloys by melting is gaining its importance in foundry sector. During recycling, some of the alloying elements present in scrap alloys eventually become trace/tramp impurities in the recycled alloy. These elements could potentially affect the alloy's microstructure and hence its mechanical properties. In the present work, an attempt has been made to investigate the effect of one of such trace elements on the microstructure and mechanical properties of A319 alloy. The element chosen for the present investigation is scandium (Sc). This paper discusses the effects of the additions of trace amount of Sc on the microstructure and mechanical properties of A319 alloy in as-cast, T6 and T7 heat treated conditions.

  6. Thermodynamic study of sublimation, melting and vaporization of scandium(III) dipivaloylmethanate derivatives

    International Nuclear Information System (INIS)

    Zherikova, Kseniya V.; Zelenina, Ludmila N.; Chusova, Tamara P.; Gelfond, Nikolay V.; Morozova, Natalia B.

    2016-01-01

    Highlights: • Thermal properties of two volatile fluorinated Sc(III) beta-diketonates were studied. • Saturated and unsaturated vapor pressures were measured. • DSC analysis was carried out. • Sublimation, evaporation and melting enthalpies and entropies were derived. • Effect of fluorine introduction on volatility and thermal stability was established. - Abstract: The present work deals with the investigation of thermal properties of two volatile scandium(III) beta-diketonates with 2,2,6,6-tetramethyl-4-fluoro-3,5-heptanedione and 1,1,1-trifluoro-5,5-dimethyl-2,4-hexanedione which have been synthesized and purified. Using the static method with glass membrane gauge-manometer the temperature dependencies of saturated and unsaturated vapor pressure were measured for the first time. The temperatures and enthalpies of melting were measured for these compounds by differential scanning calorimetry. The standard thermodynamic characteristics of enthalpy and entropy for sublimation, vaporization and melting processes were derived.

  7. Dielectric matrix, dynamical matrix and phonon dispersion in hcp transition metal scandium

    International Nuclear Information System (INIS)

    Singh, Joginder; Singh, Natthi; Prakash, S.

    1976-01-01

    Complete dielectric matrix is evaluated for hcp transition metal scandium using the non-interacting s- and d-band model. The local field corrections which are consequence of the non-diagonal part of the dielectric matrix are calculated explicitly. The free electron approximation is used for the s-electrons and the simple tight-binding approximation is used for the d-electrons. The theory developed by Singh and others is used to invert the dielectric matrix and the explicit expressions for the dynamical matrix are obtained. The phonon dispersion relations are investigated by using the renormalized Animalu transition metal model potential (TMMP) for bare ion potential. The contribution due to non-central forces which arise due to local fields is found to be 20%. The results are found in resonably good agreement with the experimental values. (author)

  8. Bottom sediment transport study at Haiphong port using radioactive scandium as tracer

    International Nuclear Information System (INIS)

    Pham Ngoc Chuong; Phan Son Hai; Pham Duy Hien

    1993-01-01

    A radioisotope tracer experiment was performed for investigating the bedload movement at the site near the access channel to Haiphong port, North Vietnam. The scandium glass and a number of mechanical devices were manufactured locally for the experiment. Simple and safe procedures were adopted for the production, transportation and injection of radioactive tracer materials. Five tracking experiments were carried out covering the period of 84 days in winter 1992-1993. The experimental results provide a firm basis for elaborating appropriate measures against the siltation problem at Haiphong port, especially for the design of a new access channel with a better orientation with respect to the directions of the water flow and bedload transport, as proposed recently by the Port Authority. (Author). 2 refs, 4 figs

  9. Modification mechanism of eutectic silicon in Al–6Si–0.3Mg alloy with scandium

    Energy Technology Data Exchange (ETDEWEB)

    Patakham, Ussadawut [Manufacturing and Systems Engineering Program, Department of Production Engineering, Faculty of Engineering, King Mongkut’s University of Technology Thonburi, 126 Pracha-Utid Rd., Bangmod, Tungkhru, Bangkok 10140 (Thailand); Kajornchaiyakul, Julathep [National Metal and Material Technology Center, National Science and Technology Development Agency, 114 Thailand Science Park, Klong Nueng, Klong Luang, Pathumthani 12120 (Thailand); Limmaneevichitr, Chaowalit, E-mail: chaowalit.lim@kmutt.ac.th [Manufacturing and Systems Engineering Program, Department of Production Engineering, Faculty of Engineering, King Mongkut’s University of Technology Thonburi, 126 Pracha-Utid Rd., Bangmod, Tungkhru, Bangkok 10140 (Thailand)

    2013-10-25

    Highlights: •Morphologies and growth of Sc and Sr-modified eutectic silicon resemble those of dendrites. •Crystal orientation of eutectic aluminum depends on growth characteristics of eutectic silicon. •We report strong evidence of the occurrence of an impurity-induced twinning mechanism. -- Abstract: The modification mechanism of eutectic silicon in Al–6Si–0.3Mg alloy with scandium was studied. The crystallographic orientation relationships between primary dendrites and the eutectic phase of unmodified and modified Al–6Si–0.3 Mg alloys were determined using electron backscatter diffraction (EBSD). The orientation of aluminum modified with scandium in the eutectic phase was different from that of the neighboring primary dendrites. This result implies that eutectic aluminum grows epitaxially from the surrounding primary aluminum dendrites in the unmodified alloy and that eutectic aluminum grows competitively from the surrounding primary aluminum dendrites in the modified alloy. The pole figure maps of eutectic Si in the [1 0 0], [1 1 0] and [1 1 1] axes of the unmodified and Sc-modified alloys were different, suggesting that the eutectic Al and Si crystals in modified alloy growth are more isotropic and cover a larger set of directions. The lattice fringes of Si of the alloys with and without Sc modification were different in the TEM results. The lattice fringes of Si in modified alloy were found to be multiple twins. However, this was not observed in the unmodified alloy. The growth characteristic of eutectic Si crystal in modified alloy suggests the occurrence of multiple twinning reactions and the formation of a high density of twins. This modification mechanism by Sc is explained by the results of scanning electron microscopy (SEM), electron backscatter diffraction (EBSD) and transmission electron microscopy (TEM) analysis, which provide strong evidence of the occurrence of the impurity-induced twinning (IIT) mechanism.

  10. Insights into the mantle geochemistry of scandium from a meta-analysis of garnet data

    Science.gov (United States)

    Chassé, Mathieu; Griffin, William L.; Alard, Olivier; O'Reilly, Suzanne Y.; Calas, Georges

    2018-06-01

    The meta-analysis of about 13,000 analyses of scandium content in garnet grains shows that, below the spinel-garnet transition, this phase carries about three-quarters of the Sc budget of the mantle, indicating its control on Sc mobility. The Sc content of garnets in mafic rocks is low, due to a dilution effect resulting from their high modal content in garnet. Garnets from ultramafic rocks exhibit a wider range of Sc concentrations. We assess the relative influence of thermobarometry, crystal chemistry and fluid-related events on the distribution of Sc in garnet from such rocks to improve the tracking of geochemical processes in the mantle. Pressure and temperature of equilibration in the mantle are second-order factors influencing the Sc content of garnet, while crystal chemistry, in particular Cr/Cr+Al and Ca/Ca+Mg, is the main parameter controlling the compatibility of Sc. Scandium is incorporated in both X and Y sites of Cr-Ca-rich garnets, resulting in a behaviour intermediate between rare-earth elements, incorporated in the X site, and trivalent transition elements, occupying the Y site. This affinity for both sites results in a mild compatibility of Sc in the garnet stability field of the mantle; hence Sc concentration in garnet increases with melt extraction and can be reduced by silicate-melt metasomatism. In contrast, metasomatism by volatile-rich fluids increases the Sc concentration in garnet. The control of garnet on the compatibility of Sc in deep lithospheric rocks demonstrates the potential of using Sc to track the conditions of formation of magmas and their residual rocks, as well as the origin and nature of metasomatic fluids.

  11. 59 Cyg and OT Gem

    Indian Academy of Sciences (India)

    2009-07-23

    Jul 23, 2009 ... of the circumstellar disk using the Hα line and also ... the time interval 1978–1987 and saw the V /R variabil- ..... Time series of 59 Cyg Hα line observed in July 2009; (Spectra are offset and labelled with the observation date,.

  12. Multiscale Study of Hydrogen Adsorption on Six Designed Covalent Organic Frameworks Based on Porphyrazine, Cyclobutane and Scandium

    International Nuclear Information System (INIS)

    Li Le-Le; Gao Teng-Fei; Zhang Ruan-Yu; Zhang Hong

    2014-01-01

    The first-principles method of hydrogen adsorption is used to investigate the interaction of H_2 with the scandium-porphyrazine (Sc-Pz) and porphyrazine (Pz) clusters. The result shows that the interaction of H_2 with Sc-Pz is stronger than with Pz. Then grand canonical Monte Carlo simulations are used to investigate hydrogen adsorption in six designed covalent organic frameworks (COFs), which are designed based on porphyrazine, cyclobutane and scandium. When the pressure is from 0.1 to 100 bar and the temperature is 298 K and 77 K, the hydrogen adsorption capacities of the six COFs are calculated. We further study the importance of Sc and fillers to improve the H_2 uptake in the modified COFs by analyzing the isosteric heat of hydrogen adsorption. (condensed matter: electronic structure, electrical, magnetic, and optical properties)

  13. 59 eyes with endogenous endophthalmitis

    DEFF Research Database (Denmark)

    Bjerrum, Søren Solborg; la Cour, Morten

    2017-01-01

    BACKGROUND: To study the epidemiology of patients with endogenous endophthalmitis in Denmark. MATERIAL AND METHODS: Retrospective and prospective case series of 59 eyes in patients with endogenous endophthalmitis in Denmark between 2000 and 2016. RESULTS: The age of the patients ranged from 28 to......, the visual outcome and the mortality of the patients. The epidemiology of the disease is very different in Scandinavia compared to Asia. The visual prognosis remains grave and the majority of the eyes lose useful vision....

  14. Scandium interaction with diantipyrylmethane homologues and 2-(n-sulphophenylazo)-1,8-dihydroxynaphthalene-3,6 sodium disulphonate

    Energy Technology Data Exchange (ETDEWEB)

    Ganago, L I; Alinovskaya, L A [AN Belorusskoj SSR, Minsk. Inst. Fiziki Tverdogo Tela i Poluprovodnikov

    1979-01-01

    The reactions of scandium with homologs of diantipyrilmethane (DAM)-propyldiantipyrilmethane (PDAM) and phenyldiantipyrilmethane (PhDAM) - are studied. The relationship of components in the complexes formed is found, and chemism of their formation is established. The complexes Sc-SPADNE (sodium salt 2-(n-sulphophenylazo)-1,8-dioxynaphthalene-3,6-disulphonic acid) are shown to form within a wide pH range. The maximum yield of complexes is observed at 6.0-7.5 pH. By the ion-exchange method the anion character of heteroligand scandium complexes is established. The complex Sc-SPADNE-PDAM is faster as compared with the complexes Sc-SPADNE-DAM and Sc-SPADNE-PhDAM. The decrease in amine excess and increase in the sensitivity of heteroligand formation of the complexes of scandium with SPADNE and PDAM make them better suited for analysis. The technique is developed for the determination of Sc/sub 2/O/sub 3/ in perovskites using the complete differential spectrophotometry method.

  15. Magnetic Moment of $^{59}$Cu

    CERN Multimedia

    2002-01-01

    Experiment IS358 uses the intense and pure beams of copper isotopes provided by the ISOLDE RILIS (resonance ionization laser ion source). The isotopes are implanted and oriented in the low temperature nuclear orientation set-up NICOLE. Magnetic moments are measured by $\\beta$-NMR. Copper (Z=29), with a single proton above the proton-magic nickel isotopes provides an ideal testground for precise shell model calculations of magnetic moments and their experimental verification. In the course of our experiments we already determined the magnetic moments of $^{67}$Ni, $^{67}$Cu, $^{68g}$Cu, $^{69}$Cu and $^{71}$Cu which provide important information on the magicity of the N=40 subshell closure. In 2001 we plan to conclude our systematic investigations by measuring the magnetic moment of the neutron-deficient isotope $^{59}$Cu. This will pave the way for a subsequent study of the magnetic moment of $^{57}$Cu with a complementary method.

  16. Phenomenological theory of the dielectric response of lead magnesium niobate and lead scandium tantalate

    International Nuclear Information System (INIS)

    Qian, H.; Bursill, L.A.

    1997-01-01

    The influence of the random field effects originating from charges chemical defects and non-domain textures of the formation and dynamics of polar clusters is analyzed. The spatial distribution of the local fields is not totally random but contains some correlations in direction and strength. Polar clusters are classified to be dynamic or frozen according to their dynamic characteristics in the random fields. The relaxation formula of a dipolar moment in an anisotropic double-well potential is deduced. Two percolation models are introduced, one to account for frustration effects associated with multiple orientations of polar clusters, which results in a broad diffuse dielectric response and the second to account for the case whereby there may be a phase transition to a ferroelectric state. The dielectric permittivity and dissipation factor of the typical relaxors lead magnesium niobate and lead scandium tantalate are predicted as a function of both temperature and frequency, which results are in good agreement with the experimental measurements. 30 refs., 9 figs

  17. Microstructure and age-hardening effects of aluminium alloys with additions of scandium and zirconium

    Energy Technology Data Exchange (ETDEWEB)

    Galun, R.; Mordike, B.L. [Inst. fuer Werkstoffkunde und Werkstofftechnik, Technische Univ. Clausthal, Clausthal-Zellerfeld (Germany); Maiwald, T.; Smola, B. [Zentrum fuer Funktionswerkstoffe GmbH, Clausthal-Zellerfeld (Germany); Mergen, R.; Manner, M.; Uitz, W. [Miba Gleitlager GmbH, Laakirchen (Australia)

    2004-12-01

    The aim of the work presented in this report was to produce age-hardenable aluminium alloys containing scandium and zirconium by a casting process with similar cooling conditions like an industrial casting process. Microstructure, precipitation structure and age-hardening response of different alloys with up to 0.4 wt.% Sc and Zr were investigated. Age-hardening experiments from the as-cast condition without solution annealing showed a significant increase of hardness of about 100% for Sc-rich alloys and of 50% for Zr-rich alloys compared to the as-cast condition. TEM investigations revealed the formation of precipitates of ternary Al{sub 3}(Sc{sub x}Zr{sub 1-x}) phases with a cubic cP4 crystal structure. In addition to the strengthening effect, a high thermal stability especially of the precipitates in Zr-rich alloys up to 400 C let these alloys look very promising for high-temperature applications. (orig.)

  18. Partitioning of Iron and Scandium in Soils Having Water Drainage Limitations

    International Nuclear Information System (INIS)

    Aide, M.; Braden, I.; Mueller, W.

    2010-01-01

    Soil chemistry of Fe includes weathering reactions, adsorption, hydrolysis, complexation, and oxidation-reduction reactions. Soil chemistry for scandium (Sc) is similar, but Sc does not include oxidation-reduction reactions. To determine if geochemical analysis may be used to identify Sc partitioning with respect to Fe among the particle size fractions, two Alfisol and two Ultisol soils were assessed using an aqua-regia digestion to estimate Sc and Fe concentrations for whole soil and particle size separates. Aqua-regia digestion data showed Sc depletion relative to Fe in sand separate. Sand separate is largely composed on quartz sand and Fe-Mn-bearing nodules, which are redoximorphic features produced by alternating oxic and suboxic/anoxic conditions associated with seasonally fluctuating water tables. Relative partitioning of Fe and Sc in these soils warrants further study to assess if selective extractions could quantify the extent of modern or ancestral oxidation-reduction processes responsible in some soil features involved in soil genesis.

  19. Effect of Aqueous Media on the Recovery of Scandium by Selective Precipitation

    Directory of Open Access Journals (Sweden)

    Bengi Yagmurlu

    2018-05-01

    Full Text Available This research presents a novel precipitation method for scandium (Sc concentrate refining from bauxite residue leachates and the effect of aqueous media on this triple-stage successive precipitation process. The precipitation pattern and the precipitation behavior of the constituent elements was investigated using different precipitation agents in three major mineral acid media, namely, H2SO4, HNO3, and HCl in a comparative manner. Experimental investigations showed behavioral similarities between HNO3 and HCl media, while H2SO4 media was different from them because of the nature of the formed complexes. NH4OH was found to be the best precipitation agent in every leaching media to remove Fe(III with low Sc co-precipitation. To limit Sc loss from the system, Fe(III removal was divided into two steps, leading to more than 90% of Fe(III removal at the end of the process. Phosphate concentrates were produced in the final step of the precipitation process with dibasic phosphates which have a strong affinity towards Sc. Concentrates containing more than 50% of ScPO4 were produced in each case from the solutions after Fe(III removal, as described. A flow diagram of the selective precipitation process is proposed for these three mineral acid media with their characteristic parameters.

  20. Adsorption of hydrogen in Scandium/Titanium decorated nitrogen doped carbon nanotube

    Energy Technology Data Exchange (ETDEWEB)

    Mananghaya, Michael, E-mail: mikemananghaya@gmail.com [De La Salle University, 2401 Taft Ave, 0922, Manila (Philippines); DLSU STC Laguna Boulevard, LTI Spine Road Barangays Biñan and Malamig, Biñan City, Laguna (Philippines); DOST-ASTHRDP, PCIEERD, Gen. Santos Ave., Bicutan, Taguig City 1631 (Philippines); Belo, Lawrence Phoa; Beltran, Arnel [De La Salle University, 2401 Taft Ave, 0922, Manila (Philippines); DLSU STC Laguna Boulevard, LTI Spine Road Barangays Biñan and Malamig, Biñan City, Laguna (Philippines)

    2016-09-01

    Nitrogen doped Carbon Nanotube with divacancy (4ND-CN{sub x}NT) that is decorated with Scandium and Titanium as potential hydrogen storage medium using the pseudo potential density functional method was investigated. Highly localized states near the Fermi level, which are derived from the nitrogen defects, contribute to strong Sc and Ti bindings, which prevent metal aggregation and improve the material stability. A detailed Comparison of the Hydrogen adsorption capability with promising system-weight efficiency of Sc over Ti was elucidated when functionalized with 4ND-CN{sub x}NT. Finally, the (Sc/4ND){sub 10}-CN{sub x}CNT composite material has a thermodynamically favorable adsorption and consecutive adsorption energy for ideal reversible adsorption and desorption of hydrogen at room temperature such that it can hold at least 5.8 wt% hydrogen molecules at the LDA and GGA level. - Highlights: • Carbon Nanotube with divacancy (4ND-CN{sub x}NT) decorated with Sc and Ti. • Nitrogen defects, contribute to strong Sc and Ti bindings. • H{sub 2} and (Sc/4ND){sub 10}-CN{sub x}CNT has a favorable adsorption. • 5.8 wt% adsorption at the LDA and GGA level.

  1. Influence of scandium on the microstructure and strength properties of the welded joint at the laser welding of aluminum-lithium alloys

    Science.gov (United States)

    Malikov, A. G.; Golyshev, A. A.; Ivanova, M. Yu.

    2017-10-01

    Today, aeronautical equipment manufacture involves up-to-date high-strength aluminum alloys of decreased density resulting from lithium admixture. Various technologies of fusible welding of these alloys are being developed. Serious demands are imposed to the welded joints of aluminum alloys in respect to their strength characteristics. The paper presents experimental investigations of the optimization of the laser welding of aluminum alloys with the scandium-modified welded joint. The effect of scandium on the micro-and macro-structure has been studied as well as the strength characteristics of the welded joint. It has been found that scandium under in the laser welding process increases the welded joint elasticity for the system Al-Mg-Li, aluminum alloy 1420 by 20 %, and almost doubles the same for the system Al-Cu-Li, aluminum alloy 1441.

  2. Laboratory studies into the use of the scandium-46-EDTA complex as a tracer for groundwater flow

    International Nuclear Information System (INIS)

    Cheng, H.; Nixon, S.C.

    1988-01-01

    Gamma ray emitting metal radionuclides, when complexed with an appropriate complexing agent, provide a wide choice of water tracers particularly for groundwater studies where a radionuclide of appropriate half-life suited to the particular study can be selected. Scandium-46 has easily detectable gamma emission and a suitable half-life (84 days) for medium term studies. It has been widely and successfully used as a tracer in studies of sediment movement but has not yet been introduced as a groundwater tracer. In our experiments the chemical aspects of the preparation of Sc-46-EDTA were studied in some detail and its behaviour in various mineralogical environments was evaluated with reference to the standard tracer, tritiated water. The experimental results have shown that the scandium cation can be easily complexed with EDTA to form soluble SC-EDTA. The complex is very stable in a wide range of pH; the adsorptive properties of Sc-EDTA in the batch studies and the retardation and recovery in the column tests in comparison with tritiated water are quite satisfactory. In general Sc-46-EDTA is a promising tracer for groundwater studies. In the report the appropriate conditions, procedures and some rational and efficient methods for testing the purity of Sc-46-EDTA in the preparation of the tracer solution of Sc-46-EDTA are described. In addition, it has been found that the formation of the metal hydroxide colloids is the major reason for the great loss in groundwater aquifers of most trivalent metal nuclide tracers in the cationic form including scandium-46. (author). 29 refs, 11 figs, 12 tabs

  3. Interaction of scandium and titanium atoms with a carbon surface containing five- and seven-membered rings

    International Nuclear Information System (INIS)

    Krasnov, P. O.; Eliseeva, N. S.; Kuzubov, A. A.

    2012-01-01

    The use of carbon nanotubes coated by atoms of transition metals to store molecular hydrogen is associated with the problem of the aggregation of these atoms, which leads to the formation of metal clusters. The quantum-chemical simulation of cluster models of the carbon surface of a graphene type with scandium and titanium atoms has been performed. It has been shown that the presence of five- and seven-membered rings, in addition to six-membered rings, in these structures makes it possible to strongly suppress the processes of the migration of metal atoms over the surface, preventing their clustering.

  4. Complexometric determination of aluminium and scandium using fluorides as masking agent at low pH value

    International Nuclear Information System (INIS)

    Tikhonov, V.N.

    1978-01-01

    A complexometric method is suggested to determine Al and Sc by back titration of Bi(NO 3 ) 3 solution with xylenol orange indicator at low pH values. To increase selectivity fluoride additions were used which were masked by boron acid at the end titration point. EDTA was used as a complexing agent. Metals which create at low pH values stable complexes with EDTA undestroyed by fluoride, do not interfere with Al and Sc determination. Scandium is shown to be determined more selectively than aluminium

  5. A59 waste repackaging database (AWARD)

    International Nuclear Information System (INIS)

    Keel, A.

    1993-06-01

    This document describes the data structures to be implemented to provide the A59 Waste Repackaging Database (AWARD); a Computer System for the in-cave Bertha waste sorting and LLW repackaging operations in A59. (Author)

  6. 33 CFR 401.59 - Pollution.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Pollution. 401.59 Section 401.59 Navigation and Navigable Waters SAINT LAWRENCE SEAWAY DEVELOPMENT CORPORATION, DEPARTMENT OF TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.59 Pollution. (a) No vessel shall: (1...

  7. 28 CFR 59.1 - Introduction.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Introduction. 59.1 Section 59.1 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GUIDELINES ON METHODS OF OBTAINING DOCUMENTARY MATERIALS HELD BY THIRD PARTIES § 59.1 Introduction. (a) A search for documentary materials necessarily involves...

  8. 40 CFR 59.514 - Circumvention.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Circumvention. 59.514 Section 59.514 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL... Compound Emission Standards for Aerosol Coatings § 59.514 Circumvention. Each manufacturer, distributor...

  9. 40 CFR 59.109 - Circumvention.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Circumvention. 59.109 Section 59.109 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL... Compound Emission Standards for Automobile Refinish Coatings § 59.109 Circumvention. Each manufacturer and...

  10. 40 CFR 59.411 - Circumvention.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Circumvention. 59.411 Section 59.411 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL... Compound Emission Standards for Architectural Coatings § 59.411 Circumvention. Each manufacturer and...

  11. 40 CFR 59.212 - Circumvention.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Circumvention. 59.212 Section 59.212 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL... Compound Emission Standards for Consumer Products § 59.212 Circumvention. No regulated entity subject to...

  12. 42 CFR 59.212 - Grantee accountability.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Grantee accountability. 59.212 Section 59.212 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.212 Grantee accountability. (a...

  13. 49 CFR 801.59 - Geological records.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Geological records. 801.59 Section 801.59... PUBLIC AVAILABILITY OF INFORMATION Exemption From Public Disclosure § 801.59 Geological records. Pursuant to 5 U.S.C. 552(b)(9), records concerning geological wells are exempt from public disclosure. ...

  14. 45 CFR 86.59 - Advertising.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Advertising. 86.59 Section 86.59 Public Welfare... in Employment in Education Programs or Activities Prohibited § 86.59 Advertising. A recipient shall not in any advertising related to employment indicate preference, limitation, specification, or...

  15. 7 CFR 15a.59 - Advertising.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Advertising. 15a.59 Section 15a.59 Agriculture Office of the Secretary of Agriculture EDUCATION PROGRAMS OR ACTIVITIES RECEIVING OR BENEFITTING FROM... Activities Prohibited § 15a.59 Advertising. A recipient shall not in any advertising related to employment...

  16. 40 CFR 59.207 - Test methods.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Test methods. 59.207 Section 59.207 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL... Compound Emission Standards for Consumer Products § 59.207 Test methods. Each manufacturer or importer...

  17. Magnetic susceptibility of scandium-hydrogen and lutetium-hydrogen solid-solution alloys from 2 to 3000K

    International Nuclear Information System (INIS)

    Stierman, R.J.

    1982-12-01

    Results for pure Sc show that the maximum and minimum in the susceptibility discovered earlier are enhanced as the impurity level of iron in scandium decreases. The Stoner enhancement factor, calculated from low-temperature heat capacity data, susceptibility data, and band-structure calculations show Sc to be a strongly enhanced paramagnet. Below 2 0 K, the magnetic anisotropy between the hard and easy directions of scandium decreases linearly with decreasing temperature, tending toward zero at 0 K. The large increase in the susceptibility of Sc at lower temperatures indicates magnetic ordering. Pure Lu and Lu-H alloys showed an anisotropy in susceptibility vs orientation; thus the samples were not random polycrystalline samples. Pure Lu shows the shallow maximum and minimum, but the increase in susceptibility at low temperatures is larger than previously observed. The susceptibility-composition dependence of the Lu-H alloys also did not match other data. The susceptibility-composition dependence does not match the composition dependence of the electronic specific heat constant below 150 K, showing the electronic specific heat is being affected by terms other than phonon-electron and pure electron-electron interactions

  18. 42 CFR 59.209 - Civil rights.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Civil rights. 59.209 Section 59.209 Public Health... Grants for Family Planning Service Training § 59.209 Civil rights. Attention is called to the requirements of Title VI of the Civil Rights Act of 1964 (78 Stat. 252, 42 U.S.C. 2000d et seq.) and in...

  19. 16 CFR 5.59 - Presiding official.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Presiding official. 5.59 Section 5.59 Commercial Practices FEDERAL TRADE COMMISSION ORGANIZATION, PROCEDURES AND RULES OF PRACTICE STANDARDS OF... Chief Administrative Law Judge, who shall appoint an Administrative Law Judge to preside over the...

  20. 28 CFR 91.59 - OJP's responsibilities.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false OJP's responsibilities. 91.59 Section 91.59 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GRANTS FOR CORRECTIONAL FACILITIES... be required. (b) Specific duties. As part of its role in the NEPA process, OJP shall: (1) Issue...

  1. 40 CFR 59.105 - Reporting requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Reporting requirements. 59.105 Section... Volatile Organic Compound Emission Standards for Automobile Refinish Coatings § 59.105 Reporting requirements. (a) Each regulated entity must submit an initial report no later than January 11, 1999 or within...

  2. 34 CFR 106.59 - Advertising.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Advertising. 106.59 Section 106.59 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION... Advertising. A recipient shall not in any advertising related to employment indicate preference, limitation...

  3. 28 CFR 51.59 - Redistrictings.

    Science.gov (United States)

    2010-07-01

    ... extent to which the plan departs from objective redistricting criteria set by the submitting jurisdiction... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Redistrictings. 51.59 Section 51.59 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR THE ADMINISTRATION OF SECTION 5 OF...

  4. C59N Peapods Sensing the Temperature

    Directory of Open Access Journals (Sweden)

    Toshiro Kaneko

    2013-01-01

    Full Text Available We report the novel photoresponse of nanodevices made from azafullerene (C59N-encapsulated single-walled carbon nanotubes (C59N@SWNTs, so called peapods. The photoconducting properties of a C59N@SWNT are measured over a temperature range of 10 to 300 K under a field-effect transistor configuration. It is found that the photosensitivity of C59N@SWNTs depends very sensitively on the temperature, making them an attractive candidate as a component of nanothermometers covering a wide temperature range. Our results indicate that it is possible to read the temperature by monitoring the optoelectronics signal of C59N@SWNTs. In particular, sensing low temperatures would become more convenient and easy by giving a simple light pulse.

  5. Self-Assembled Nanocomposite Organic Polymers with Aluminum and Scandium as Heterogeneous Water-Compatible Lewis Acid Catalysts.

    Science.gov (United States)

    Miyamura, Hiroyuki; Sonoyama, Arisa; Hayrapetyan, Davit; Kobayashi, Shū

    2015-09-01

    While water-compatible Lewis acids have great potential as accessible and environmentally benign catalysts for various organic transformations, efficient immobilization of such Lewis acids while keeping high activity and without leaching of metals even under aqueous conditions is a challenging task. Self-assembled nanocomposite catalysts of organic polymers, carbon black, aluminum reductants, and scandium salts as heterogeneous water-compatible Lewis acid catalysts are described. These catalysts could be successfully applied to various C-C bond-forming reactions without leaching of metals. Scanning transmission electron microscopy analyses revealed that the nanocomposite structure of Al and Sc was fabricated in these heterogeneous catalysts. It is noted that Al species, which are usually decomposed rapidly in the presence of water, are stabilized under aqueous conditions. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Scandium doping brings speed improvement in Sb2Te alloy for phase change random access memory application.

    Science.gov (United States)

    Chen, Xin; Zheng, Yonghui; Zhu, Min; Ren, Kun; Wang, Yong; Li, Tao; Liu, Guangyu; Guo, Tianqi; Wu, Lei; Liu, Xianqiang; Cheng, Yan; Song, Zhitang

    2018-05-01

    Phase change random access memory (PCRAM) has gained much attention as a candidate for nonvolatile memory application. To develop PCRAM materials with better properties, especially to draw closer to dynamic random access memory (DRAM), the key challenge is to research new high-speed phase change materials. Here, Scandium (Sc) has been found it is helpful to get high-speed and good stability after doping in Sb 2 Te alloy. Sc 0.1 Sb 2 Te based PCRAM cell can achieve reversible switching by applying even 6 ns voltage pulse experimentally. And, Sc doping not only promotes amorphous stability but also improves the endurance ability comparing with pure Sb 2 Te alloy. Moreover, according to DFT calculations, strong Sc-Te bonds lead to the rigidity of Sc centered octahedrons, which may act as crystallization precursors in recrystallization process to boost the set speed.

  7. Random-field Potts model for the polar domains of lead magnesium niobate and lead scandium tantalate

    Energy Technology Data Exchange (ETDEWEB)

    Qian, H.; Bursill, L.A

    1997-06-01

    A random filed Potts model is used to establish the spatial relationship between the nanoscale distribution of charges chemical defects and nanoscale polar domains for the perovskite-based relaxor materials lead magnesium niobate (PMN) and lead scandium tantalate (PST). The random fields are not set stochastically but are determined initially by the distribution of B-site cations (Mg, Nb) or (Sc, Ta) generated by Monte Carlo NNNI-model simulations for the chemical defects. An appropriate random field Potts model is derived and algorithms developed for a 2D lattice. It is shown that the local fields are strongly correlated with the chemical domain walls and that polar domains as a function of decreasing temperature is simulated for the two cases of PMN and PST. The dynamics of the polar clusters is also discussed. 33 refs., 9 figs.

  8. Modification of radiation sensitivity by salts of the metals beryllium and indium and the rare earths cerium, lanthanum and scandium

    International Nuclear Information System (INIS)

    Floersheim, G.L.

    1995-01-01

    The LD 50 of 46 salts of metals and rare earths (lanthanoids) was determined in mice. Half the LD 50 of the compounds was then combined with lethal radiation (10.5 Gy) and the modification of survival time was scored. Only the metals beryllium and indium and the rare earths cerium, lanthanum and scandium displayed activity in our assay. There were then tested at a wider range of lower doses and reduced survival time in a dose-dependent fashion. This appears to be compatible with enhancement of radiation sensitivity. The interaction of these metals and rare earths with radiation adds a new facet to their toxicological spectrum and, by enhancing radiation effects, may influence estimates of risk. On the other hand, radiosensitizing properties of the metals may be useful for further development of compounds to be used as adjuncts in specific situations of cancer radiotherapy. 31 refs., 1 fig., 1 tab

  9. A59 waste repackaging database (AWARD)

    International Nuclear Information System (INIS)

    Keel, A.

    1993-06-01

    This paper sets out the requirements for AWARD (the A59 Waste Repackaging Database); a computer-based system to record LLW sorting and repacking information from the North Cave Line in A59. A solution will be developed on the basis of this document. AWARD will record and store details entered from waste sorting and LLW repackaging operations. This document will be used as the basis of the development of the host computer system. (Author)

  10. Study of strength properties of semi-finished products from economically alloyed high-strength aluminium-scandium alloys for application in automobile transport and shipbuilding

    Science.gov (United States)

    Baranov, Vladimir; Sidelnikov, Sergey; Zenkin, Evgeny; Frolov, Viktor; Voroshilov, Denis; Yakivyuk, Olga; Konstantinov, Igor; Sokolov, Ruslan; Belokonova, Irina

    2018-04-01

    The results of a study on the strength of rolled products from aluminium alloys doped with scandium under various processing conditions of hot and cold rolling are presented. The regularities of metal flow and the level of strength of deformed semi-finished products from aluminum-scandium alloys are established, depending on the total degree of deformation and the various modes of single reduction during rolling. It is shown that when using one heating of a cast billet to obtain high-quality semi-finished products, the temperature during the rolling process should not be lower than 350-370°, and the total degree of deformation does not exceed 50-60%. It was found that the semi-finished products from alloys with a content of scandium in the range 0.11-0.12% in the deformed state had elevated values of ultimate tensile strength and yield strength of the metal, which allows them to be recommended for industrial production of sheet metal products.

  11. Development of methods for the selective separation of scandium, zirconium and tin for radiopharmaceutical applications; Entwicklung von Methoden zur selektiven Trennung von Scandium, Zirkonium und Zinn fuer radiopharmazeutische Anwendungen

    Energy Technology Data Exchange (ETDEWEB)

    Dirks-Fandrei, Carina

    2014-07-01

    The subject of the present work is the development of fast and highly selective methods for the separation and purification of scandium, zirconium and tin radionuclides from potential target materials for use in nuclear medicine. A number of selected resins (TrisKem International) were first characterized with respect to their extraction behaviour towards a large number of cations. Characterization studies were performed in batch experiments by determination of weight distribution ratios D{sub w} and further the influence of interferences on the uptake of these elements was evaluated. Weight distribution ratios were determined in different acids and acid concentrations with main focus on scandium, tin or zirconium. The interference of macro amounts of Calcium and Ti on the Sc extraction was evaluated as well as the interference of macro amounts of Y on the Zr extraction. Best suited uptake conditions were found for Scandium on DGA were determined to be 2.5 M HNO{sub 3} for Ti-Targets and 0.1 M HNO{sub 3} for Calcium-Targets. Otherwise it is also possible to extract Sc with TRU Resin. High uptakes were obtained at 2.5 M HNO{sub 3} for simulated Ti- and Calcium-targets. Separation methods were developed using elution studies; employed conditions were chosen according to parameters evaluated in the batch-experiment. The developed methods allowed separating Sc very rapidly in high purity very rapidly from Ti- or Calcium-targets. For Zr a separation method based on UTEVA Resin has been developed. Following results of batch experiments simulated Y-target solution were loaded onto a UTEVA resin column from 6 M HNO{sub 3}; the elution of Zr could be performed in 0.01 M oxalic acid. Decontamination factors in the order of 10{sup 4}-10{sup 5} could be obtained applying the developed method; the method thus allowed separating Zr in a high purity. Initial testing of a method for the separation of Sn from Cd targets based on the use of TBP Resin showed that the TBP resin seems

  12. BARNARD 59: NO EVIDENCE FOR FURTHER FRAGMENTATION

    Energy Technology Data Exchange (ETDEWEB)

    Roman-Zuniga, C. G. [Instituto de Astronomia, Universidad Nacional Autonoma de Mexico, Km 103 Carr. Tijuana-Ensenada, Ensenada BC 22860 (Mexico); Frau, P.; Girart, J. M. [Institut de Ciencies de l' Espai (CSIC-IEEC), Campus UAB, Facultat de Ciencies, Torre C-5p, 08193 Bellaterra, Catalunya (Spain); Alves, Joao F., E-mail: croman@astrosen.unam.mx [Institute of Astronomy, University of Vienna, Tuerkenschanzstr. 17, 1180 Vienna (Austria)

    2012-03-10

    The dense molecular clump at the center of the Barnard 59 (B59) complex is the only region in the Pipe Nebula that has formed a small, stellar cluster. The previous analysis of a high-resolution near-IR dust extinction map revealed that the nuclear region in B59 is a massive, mostly quiescent clump of 18.9 M{sub Sun }. The clump shows a monolithic profile, possibly indicating that the clump is on the way to collapse, with no evident fragmentation that could lead to another group of star systems. In this paper, we present new analysis that compares the dust extinction map with a new dust emission radio-continuum map of higher spatial resolution. We confirm that the clump does not show any significant evidence for prestellar fragmentation at scales smaller than those probed previously.

  13. BARNARD 59: NO EVIDENCE FOR FURTHER FRAGMENTATION

    International Nuclear Information System (INIS)

    Román-Zúñiga, C. G.; Frau, P.; Girart, J. M.; Alves, João F.

    2012-01-01

    The dense molecular clump at the center of the Barnard 59 (B59) complex is the only region in the Pipe Nebula that has formed a small, stellar cluster. The previous analysis of a high-resolution near-IR dust extinction map revealed that the nuclear region in B59 is a massive, mostly quiescent clump of 18.9 M ☉ . The clump shows a monolithic profile, possibly indicating that the clump is on the way to collapse, with no evident fragmentation that could lead to another group of star systems. In this paper, we present new analysis that compares the dust extinction map with a new dust emission radio-continuum map of higher spatial resolution. We confirm that the clump does not show any significant evidence for prestellar fragmentation at scales smaller than those probed previously.

  14. STAR FORMATION NEAR BERKELEY 59: EMBEDDED PROTOSTARS

    Energy Technology Data Exchange (ETDEWEB)

    Rosvick, J. M. [Department of Physical Sciences, Thompson Rivers University, 900 McGill Road, Kamloops, BC V2C 0C8 (Canada); Majaess, D. [Department of Astronomy and Physics, Saint Mary' s University, Halifax, NS B3H 3C3 (Canada)

    2013-12-01

    A group of suspected protostars in a dark cloud northwest of the young (∼2 Myr) cluster Berkeley 59 and two sources in a pillar south of the cluster have been studied in order to determine their evolutionary stages and ascertain whether their formation was triggered by Berkeley 59. Narrowband near-infrared observations from the Observatoire du Mont Mégantic, {sup 12}CO (J = 3-2) and SCUBA-2 (450 and 850 μm) observations from the JCMT, 2MASS, and WISE images, and data extracted from the IPHAS survey catalog were used. Of 12 sources studied, two are Class I objects, while three others are flat/Class II, one of which is a T Tauri candidate. A weak CO outflow and two potential starless cores are present in the cloud, while the pillar possesses substructure at different velocities, with no outflows present. The CO spectra of both regions show peaks in the range v {sub LSR} = –15 to –17 km s{sup –1}, which agrees with the velocity adopted for Berkeley 59 (–15.7 km s{sup –1}), while spectral energy distribution models yield an average interstellar extinction A{sub V} and distance of 15 ± 2 mag and 830 ± 120 pc, respectively, for the cloud, and 6.9 mag and 912 pc for the pillar, indicating that the regions are in the same vicinity as Berkeley 59. The formation of the pillar source appears to have been triggered by Berkeley 59. It is unclear whether Berkeley 59 triggered the association's formation.

  15. Paediatric liver transplantation in Johannesburg revisited: 59 ...

    African Journals Online (AJOL)

    Of the 57 patients, 45 are alive and well with actuarial 1-year patient and graft survival of 85% and 84% and 5-year patient and graft survival of 78% and 74%, respectively. Sixteen (25.42%) biliary complications occurred in 15 of our 59 transplants. Seven patients developed significant vascular complications. Comparing ...

  16. A59 waste repackaging database (AWARD)

    International Nuclear Information System (INIS)

    Keel, A.

    1993-06-01

    This document describes the software modules to be implemented to provide the user interface for the A59 Waste Repackaging Database (AWARD). The modules will consist of a front end menu with options giving access to the various screen forms and printed reports. (Author)

  17. 7 CFR 319.59-1 - Definitions.

    Science.gov (United States)

    2010-01-01

    ..., DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Wheat Diseases § 319.59-1 Definitions. Administrator... disease caused by the fungus Tilletia indica (Mitra) Mundkur. Plant. Any plant (including any plant part) for or capable of propagation, including a tree, a tissue culture, a plantlet culture, pollen, a shrub...

  18. 49 CFR 192.59 - Plastic pipe.

    Science.gov (United States)

    2010-10-01

    ... Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Materials § 192.59 Plastic pipe. (a) New plastic pipe...

  19. 33 CFR 151.59 - Placards.

    Science.gov (United States)

    2010-07-01

    ... Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION VESSELS... Pertains to Pollution from Ships Garbage Pollution and Sewage § 151.59 Placards. (a) This section applies... following: (1) The discharge of plastic or garbage mixed with plastic into any waters is prohibited. (2) The...

  20. Thermal, spectroscopic and laser properties of Nd3+ in gadolinium scandium gallium garnet crystal produced by optical floating zone method

    Science.gov (United States)

    Tian, Li; Wang, Shuxian; Wu, Kui; Wang, Baolin; Yu, Haohai; Zhang, Huaijin; Cai, Huaqiang; Huang, Hui

    2013-12-01

    A neodymium-doped gadolinium scandium gallium garnet (Nd:GSGG) single crystal with dimensions of Φ 5 × 20 mm2 has been grown by means of optical floating zone (OFZ). X-ray powder diffraction (XRPD) result shows that the as-grown Nd:GSGG crystal possesses a cubic structure with space group Ia3d and a cell parameter of a = 1.2561 nm. Effective elemental segregation coefficients of the Nd:GSGG as-grown crystal were calculated by using X-ray fluorescence (XRF). The thermal properties of the Nd:GSGG crystal were systematically studied by measuring the specific heat, thermal expansion and thermal diffusion coefficient, and the thermal conductivity of this crystal was calculated. The absorption and luminescence spectra of Nd:GSGG were measured at room temperature (RT). By using the Judd-Ofelt (J-O) theory, the theoretical radiative lifetime was calculated and compared with the experimental result. Continuous wave (CW) laser performance was achieved with the Nd:GSGG at the wavelength of 1062 nm when it was pumped by a laser diode (LD). A maximum output power of 0.792 W at 1062 nm was obtained with a slope efficiency of 11.89% under a pump power of 7.36 W, and an optical-optical conversion efficiency of 11.72%.

  1. The determination of iron-59 in water

    International Nuclear Information System (INIS)

    Zhao Min; Ban Ying

    1993-06-01

    A method to analyse iron-59 in water is introduced. The procedure of this method includes concentration by co-precipitation with hydroxides purification by anion exchange, electrodeposition in NH 4 H 2 PO 4 -(NH 4 ) 2 CO 3 system and final measurements of beta activity with a background beta-counter. The effect of iron carrier amount and pH value of water sample on the carrying Fe-59, and the effect of concentration hydrochloric acid, flowrate of adsorption and elutriation with 6 mol/L HCl-1% H 2 O 2 solution on the adsorption efficiency have been studied. The experimental results indicate that for 101 water sample, both the chemical and radiochemical yields are greater than 90%. For 51 Cr, 60 Co, 65 Zn, 95 Zr- 95 Nb and 137 Cs the decontamination factor is greater than 10 3 . The minimum detectable limit of this method is 3.8 x 10 -3 Bq/L

  2. 10CFR50.59 safety evaluations

    International Nuclear Information System (INIS)

    Grime, L.; Page, E.

    1987-01-01

    As a plant changes from the design phase to the operational phase, new regulations and standards apply. One such regulation is 10CFR50.59 on safety evaluations. Once an operating license is issued, it is mandatory to submit all applicable changes, tests, and experiments to the safety evaluation process. As preparation for this transition, Detroit Edison had procedures in place and conducted personnel training. Reviews of the safety engineering were conducted by the on-site review board. The off-site board delegated detailed reviews of most safety evaluations to the independent safety evaluation group (ISEG). The on-site group review included presentation of complete design packages by engineers. The ISEG and off-site review group's activity focused on safety evaluation. This paper addresses industry trends that were studied, Detroit Edison's recent actions, and industry issues related to 10CFR50.59 safety evaluations

  3. Determination of 59Ni in radioactive waste

    International Nuclear Information System (INIS)

    Fisera, O.; Sebesta, F.

    2010-01-01

    Composite material PAN-DMG, containing chelating agent dimethylglyoxime (DMG) immobilized in porous matrix of binding polymer polyacrylonitrile (PAN), was used for nickel separation and concentration. Method for preparation of 59 Ni source for low energy photon spectrometry was developed using homogeneous precipitation of nickel with DMG. The proposed method was tested with two types of real radioactive waste (boric acid concentrate from nuclear power plant (NPP) evaporator and spent ion exchanger from NPP). (author)

  4. 59 MDW/Science and Technology Poster

    Science.gov (United States)

    2017-04-28

    the Air Force, and Science and Engineering community Employ innov1tlve technologies ind lj)prOIChH to sustain health, performance ind revolutionize...Medics Through Patient.Centered Care Our Goals Provide technic1I expertise and resources, project management assistance, direction, ind...SGYU SUBJECT: Professional Presentation Approval • ’ ...... -""""’ ~ 18 APR 20 17 1. Your paper, entitled 59 MDW/ Science & Technology Poster

  5. Potential for photocatalytic degradation of the potassic diclofenac using scandium and silver modified titanium dioxide thin films; Potencial de degradacao fotocatalitica do diclofenaco potassico utilizando filmes finos de dioxido de titanio modificado com escandio e prata

    Energy Technology Data Exchange (ETDEWEB)

    Ciola, R.A.; Oliveira, C.T.; Lopes, S.A.; Cavalheiro, A.A., E-mail: rafaelciola@hotmail.com [Universidade Estadual de Mato Grosso do Sul (UFMS), Navirai, MS (Brazil). Centro de Pesquisas Tecnologicas em Recursos Naturais

    2011-07-01

    The potential for photocatalytic degradation of the potassic diclofenac drug was investigated using titanium dioxide thin films modified with two modifier types, scandium and silver, both prepared by Sol-Gel method. It was demonstrated by UVVis spectroscopy analysis of the solutions containing the drug, under UV-A light irradiation that the degradation efficiency of the titanium dioxide photocatalyst is dependent of the semiconductor nature and that the scandium accelerates the first step of the degradation when compared to the silver. This result seems to be related to the redox potential of the electron-hole pair, once the scandium modifying sample generates a p type semiconductor that reduces the band gap. The extra holes attract more strongly the chorine ion present in diclofenac and leading to the releasing more easily. However, after the first byproducts degradation the following steps are not facilitated, making the silver modifying more advantageous. (author)

  6. Determination of rare-earth elements, yttrium and scandium in manganese nodules by inductively-coupled argon-plastma emission spectrometry

    Science.gov (United States)

    Fries, T.; Lamothe, P.J.; Pesek, J.J.

    1984-01-01

    A sequential-scanning, inductively-coupled argon plasma emission spectrometer is used for the determination of the rare-earth elements, plus yttrium and scandium, in manganese nodules. Wavelength selection is optimized to minimize spectral interferences from manganese nodule components. Samples are decomposed with mixed acids in a sealed polycarbonate vessel, and elements are quantified without further treatment. Results for U.S. Geological Survey manganese nodule standards A-1 and P-1 had average relative standard deviations of 6.8% and 8.1%, respectively, and results were in good agreement with those obtained by other methods. ?? 1984.

  7. Structural characteristics and physical properties of diortho(pyro)silicate crystals of lanthanides yttrium and scandium grown by the Czochralski technique

    Energy Technology Data Exchange (ETDEWEB)

    Anan' eva, G.V.; Karapetyan, V.E.; Korovkin, A.M.; Merkulyaeva, T.I.; Peschanskaya, I.A.; Savinova, I.P.; Feofilov, P.P. (Gosudarstvennyj Opticheskij Inst., Leningrad (USSR))

    1982-03-01

    Optically uniform monocrystals of diortho (pyro) silicates of lanthanides, yttrium, and scandium were grown by the Czochralski technique. Four structural types of Ln/sub 2/(Si/sub 2/O/sub 7/) crystals were determined by the roentgenographic method. The presence of structural subgroups was also supported by the method of spectroscopic probes. Structural parameters were determined and data on certain physical properties (fusion temperature, density, refractive indices, transparency) of investigated crystals were presented. The generation of induced emission at lambda=1.057 ..mu..m was obtained in La/sub 2/(Si/sub 2/O/sub 7/)-Nd/sup 3 +/ crystal.

  8. Scandium complexes: physico-chemical study and evaluation of stability in vitro and in vivo for nuclear medicine application

    International Nuclear Information System (INIS)

    Kerdjoudj, Rabha

    2014-01-01

    Among the different isotopes of Scandium that can be used in nuclear medicine may be mentioned the 47 Sc and 44 Sc. The first decays by emitting an electron associated with a 159 keV gamma can thus be used either for radiotherapy or TEMP imaging. The 44 Sc (3.97 h) decays in 94.27% in case by emitting a positron, with a γ photon energy equal to 1.157 MeV. This isotope is then an ideal candidate for applications in PET imaging. Currently, the Cyclotron of high energy and high intensity ARRONAX produce 44 Sc and co-produces the isomeric state the 44m Sc (2.44 d). The 44m Sc has properties (E(γ) = 270 keV, 98.8%), which allows to consider its use as a potential in vivo generator. Previous work had demonstrated that the DOTA ligand is most suitable and stable for Sc. This thesis aims; make in evidence the feasibility of the in vivo 44m / 44 Sc generator. Initially a procedure was optimized and validated for the production of 44m / 44 Sc with a high specific activity and chemical purity. Radiolabeling of DOTA conjugated peptides was then developed and optimized. Theoretical and experimental studies have been performed in order to demonstrate the feasibility of 44m / 44 Sc as a potential in vivo generator. Finally, in vitro stability studies on radiolabeled 44m / 44 Sc complexes were performed, followed by biodistribution studies and PET imaging. (author)

  9. Determination of scandium in acid mine drainage by ICP-OES with flow injection on-line preconcentration using oxidized multiwalled carbon nanotubes.

    Science.gov (United States)

    Jerez, Javier; Isaguirre, Andrea C; Bazán, Cristian; Martinez, Luis D; Cerutti, Soledad

    2014-06-01

    An on-line scandium preconcentration and determination system implemented with inductively coupled plasma optical emission spectrometry associated with flow injection was studied. Trace amounts of scandium were preconcentrated by sorption on a minicolumn packed with oxidized multiwalled carbon nanotubes, at pH 1.5. The retained analyte was removed from the minicolumn with 30% (v/v) nitric acid. A total enrichment factor of 225-fold was obtained within a preconcentration time of 300 s (for a 25 mL sample volume). The overall time required for preconcentration and elution of 25 mL of sample was about 6 min; the throughput was about 10 samples per hour. The value of the detection limit was 4 ng L(-1) and the precision for 10 replicate determinations at 100 ng L(-1) Sc level was 5% relative standard deviation, calculated from the peak heights obtained. The calibration graph using the preconcentration system was linear with a correlation coefficient of 0.9996 at levels near the detection limits up to at least 10 mg L(-1). After optimization, the method was successfully applied to the determination of Sc in an acid drainage from an abandoned mine located in the province of San Luis, Argentina. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. Effects of scandium and zirconium combination alloying on as-cast microstructure and mechanical properties of Al-4Cu-1.5Mg alloy

    Directory of Open Access Journals (Sweden)

    Xiang Qingchun

    2011-02-01

    Full Text Available The influences of minor scandium and zirconium combination alloying on the as-cast microstructure and mechanical properties of Al-4Cu-1.5Mg alloy have been experimentally investigated. The experimental results show that when the minor elements of scandium and zirconium are simultaneously added into the Al-4Cu-1.5Mg alloy, the as-cast microstructure of the alloy is effectively modified and the grains of the alloy are greatly refined. The coarse dendrites in the microstructure of the alloy without Sc and Zr additions are refined to the uniform and fine equiaxed grains. As the additions of Sc and Zr are 0.4% and 0.2%, respectively, the tensile strength, yield strength and elongation of the alloy are relatively better, which are 275.0 MPa, 176.0 MPa and 8.0% respectively. The tensile strength is increased by 55.3%, and the elongation is nearly raised three times, compared with those of the alloy without Sc and Zr additions.

  11. Synthesis, structures, and electroluminescent properties of scandium N,O-chelated complexes toward near-white organic light-emitting diodes.

    Science.gov (United States)

    Katkova, Marina A; Balashova, Tatyana V; Ilichev, Vasilii A; Konev, Alexey N; Isachenkov, Nikolai A; Fukin, Georgy K; Ketkov, Sergey Yu; Bochkarev, Mikhail N

    2010-06-07

    Three members of a new class of electroluminescent, neutral, and monomeric scandium N,O-chelate complexes, namely, Sc(III)-tris-2-(2-benzoimidazol-2-yl)phenolate (1), Sc(III)-tris-2-(2-benzoxyazol-2-yl)phenolate (2), and Sc(III)-tris-2-(2-benzothiazol-2-yl)phenolate (3), have been prepared and X-ray characterized. DFT calculations have been performed. In contrast to the most frequently applied dual or multiple dopants in multilayer white OLED devices, all our simpler devices with the configuration of indium tin oxide/N,N'-bis(3-methylphenyl)-N,N'-diphenylbenzidine/neat scandium complex/Yb exhibit close to near-white emission with a blue hue (CIE(x,y) = 0.2147, 0.2379) in the case of 1, a cyan hue (0.2702, 0.3524) in the case of 2, and a yellowish hue (0.3468; 0.4284) in the case of 3.

  12. 46 CFR 59.10-30 - Seal welding.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Seal welding. 59.10-30 Section 59.10-30 Shipping COAST... VESSELS AND APPURTENANCES Welding Repairs to Boilers and Pressure Vessels in -Service § 59.10-30 Seal welding. Where leaks occur in riveted joints or connections, they shall be carefully investigated to...

  13. 20 CFR 617.59 - Agreements with State agencies.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Agreements with State agencies. 617.59 Section 617.59 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR TRADE... § 617.59 Agreements with State agencies. (a) Authority. Before performing any function or exercising any...

  14. 25 CFR 141.59 - Customer complaint procedures.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Customer complaint procedures. 141.59 Section 141.59... THE NAVAJO, HOPI AND ZUNI RESERVATIONS Enforcement Powers, Procedures and Remedies § 141.59 Customer complaint procedures. (a) Any customer of a licensee may file a complaint with the Commissioner alleging...

  15. 32 CFR 1605.59 - Signing official papers.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Signing official papers. 1605.59 Section 1605.59 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM SELECTIVE SERVICE SYSTEM ORGANIZATION Local Boards § 1605.59 Signing official papers. Official papers issued by a local...

  16. 7 CFR 59.301 - Mandatory Daily Reporting for Lambs.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Mandatory Daily Reporting for Lambs. 59.301 Section 59... (CONTINUED) LIVESTOCK MANDATORY REPORTING Lamb Reporting § 59.301 Mandatory Daily Reporting for Lambs. (a) In... prices for lambs (per hundredweight) established on that day as F.O.B. feedlot or delivered at the plant...

  17. 14 CFR 1260.59 - Choice of law.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Choice of law. 1260.59 Section 1260.59... Special Conditions § 1260.59 Choice of law. Choice of Law October 2000 The rights and obligations of the parties to the grant (or cooperative agreement) shall be ascertainable by recourse to the laws of the...

  18. 40 CFR 205.59 - Recall of noncomplying vehicles.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recall of noncomplying vehicles. 205.59 Section 205.59 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.59 Recall...

  19. Two anionically derivatized scandium oxoselenates(IV): ScF[SeO3] and Sc2O2[SeO3

    Science.gov (United States)

    Greiner, Stefan; Chou, Sheng-Chun; Schleid, Thomas

    2017-02-01

    Scandium fluoride oxoselenate(IV) ScF[SeO3] and scandium oxide oxoselenate(IV) Sc2O2[SeO3] could be synthesized through solid-state reactions. ScF[SeO3] was obtained phase-pure, by reacting mixtures of Sc2O3, ScF3 and SeO2 (molar ratio: 1:1:3) together with CsBr as fluxing agent in corundum crucibles embedded into evacuated glassy silica ampoules after firing at 700 °C for seven days. Sc2O2[SeO3] first emerged as by-product during the attempts to synthesize ScCl[SeO3] following aforementioned synthesis route and could later be reproduced from appropriate Sc2O3/SeO3 mixtures. ScF[SeO3] crystallizes monoclinically in space group P21/m with a=406.43(2), b =661.09(4), c=632.35(4) pm, β=93.298(3)° and Z=2. Sc2O2[SeO3] also crystallizes in the monoclinic system, but in space group P21/n with a=786.02(6), b=527.98(4), c=1086.11(8) pm, β=108.672(3)° for Z=4. The crystal structures of both compounds are strongly influenced by the stereochemically active lone pairs of the ψ1-tetrahedral [SeO3]2- anions. They also show partial structures, where the derivatizing F- or O2- anions play an important role. For ScF[SeO3] chains of the composition 2+∞ 1[FS c 2 / 2 ] form from connected [FSc2]5+ dumbbells, while [OSc3]7+ pyramids and [OSc4]10+ tetrahedra units are condensed to layers according to 2+ ∞ 2[O2Sc2 ] in Sc2O2[SeO3].

  20. Copper scandium zirconium phosphate

    DEFF Research Database (Denmark)

    Bond, Andrew David; Warner, Terence Edwin

    2013-01-01

    The title compound, with nominal formula Cu(2)ScZr(PO(4))(3), has a beige coloration and displays fast Cu(+) cation conduction at elevated temperatures. It adopts a NASICON-type structure in the space group R3c. The examined crystal was an obverse-reverse twin with approximately equal twin compon...

  1. Zeeman spectrum of scandium

    International Nuclear Information System (INIS)

    Lulu, B.A.

    1980-09-01

    The spectra of Sc I, Sc II, Sc III, and Sc IV are analyzed through the use of the Zeeman effect. A sliding spark of the author's design is used in conjunction with a 27 kilogauss electromagnet. The spectra have (reciprocal) dispersions of 0.2 to 0.5 A/mm. 10 Sc I levels, 16 Sc II levels and 5 Sc III levels show Zeeman splitting. No Sc IV Zeeman patterns were observed. 2 Sc I, 4 Sc II, and all of the Sc III level data are new

  2. Measurement of soluble CD59 in CSF in demyelinating disease: Evidence for an intrathecal source of soluble CD59.

    Science.gov (United States)

    Zelek, Wioleta M; Watkins, Lewis M; Howell, Owain W; Evans, Rhian; Loveless, Sam; Robertson, Neil P; Beenes, Marijke; Willems, Loek; Brandwijk, Ricardo; Morgan, B Paul

    2018-02-01

    CD59, a broadly expressed glycosylphosphatidylinositol-anchored protein, is the principal cell inhibitor of complement membrane attack on cells. In the demyelinating disorders, multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD), elevated complement protein levels, including soluble CD59 (sCD59), were reported in cerebrospinal fluid (CSF). We compared sCD59 levels in CSF and matched plasma in controls and patients with MS, NMOSD and clinically isolated syndrome (CIS) and investigated the source of CSF sCD59 and whether it was microparticle associated. sCD59 was quantified using enzyme-linked immunosorbent assay (ELISA; Hycult; HK374-02). Patient and control CSF was subjected to western blotting to characterise anti-CD59-reactive materials. CD59 was localised by immunostaining and in situ hybridisation. CSF sCD59 levels were double those in plasma (CSF, 30.2 ng/mL; plasma, 16.3 ng/mL). Plasma but not CSF sCD59 levels differentiated MS from NMOSD, MS from CIS and NMOSD/CIS from controls. Elimination of microparticles confirmed that CSF sCD59 was not membrane anchored. CSF levels of sCD59 are not a biomarker of demyelinating diseases. High levels of sCD59 in CSF relative to plasma suggest an intrathecal source; CD59 expression in brain parenchyma was low, but expression was strong on choroid plexus (CP) epithelium, immediately adjacent the CSF, suggesting that this is the likely source.

  3. 29 CFR 531.59 - The tip wage credit.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false The tip wage credit. 531.59 Section 531.59 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS WAGE PAYMENTS UNDER THE FAIR LABOR STANDARDS ACT OF 1938 Interpretations Payment of Wages to Tipped Employees...

  4. 34 CFR 200.59 - Duties of paraprofessionals.

    Science.gov (United States)

    2010-07-01

    ...) Conducting parent involvement activities. (5) Providing instructional support in a library or media center... 34 Education 1 2010-07-01 2010-07-01 false Duties of paraprofessionals. 200.59 Section 200.59 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY...

  5. 46 CFR 188.10-59 - Recognized classification society.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Recognized classification society. 188.10-59 Section 188... VESSELS GENERAL PROVISIONS Definition of Terms Used in This Subchapter § 188.10-59 Recognized classification society. This term means the American Bureau of Shipping or other classification society...

  6. 28 CFR 345.59 - Inmate performance pay.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Inmate performance pay. 345.59 Section... INDUSTRIES (FPI) INMATE WORK PROGRAMS Inmate Pay and Benefits § 345.59 Inmate performance pay. Inmate workers for FPI may also receive Inmate Performance Pay for participation in programs where this award is made...

  7. 47 CFR 80.59 - Compulsory ship inspections.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Compulsory ship inspections. 80.59 Section 80... STATIONS IN THE MARITIME SERVICES Applications and Licenses § 80.59 Compulsory ship inspections. (a) Inspection of ships subject to the Communications Act or the Safety Convention. (1) The FCC will not normally...

  8. 14 CFR 63.59 - Retesting after failure.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Retesting after failure. 63.59 Section 63.59 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED... failure. (a) An applicant for a flight navigator certificate who fails a written or practical test for...

  9. 10 CFR 74.59 - Quality assurance and accounting requirements.

    Science.gov (United States)

    2010-01-01

    ... measurement system in question must not be used for material control and accounting purposes until it has been... 10 Energy 2 2010-01-01 2010-01-01 false Quality assurance and accounting requirements. 74.59 Section 74.59 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) MATERIAL CONTROL AND ACCOUNTING OF SPECIAL...

  10. 7 CFR 59.302 - Mandatory weekly reporting for lambs.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Mandatory weekly reporting for lambs. 59.302 Section... (CONTINUED) LIVESTOCK MANDATORY REPORTING Lamb Reporting § 59.302 Mandatory weekly reporting for lambs. (a... domestic from imported market purchases: (1) The quantity of lambs purchased through a negotiated purchase...

  11. 36 CFR 902.59 - Geological and geophysical information.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Geological and geophysical information. 902.59 Section 902.59 Parks, Forests, and Public Property PENNSYLVANIA AVENUE DEVELOPMENT... Geological and geophysical information. Any geological or geophysical information and data (including maps...

  12. 40 CFR 279.59 - Management of residues.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Management of residues. 279.59 Section 279.59 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED... Management of residues. Owners and operators who generate residues from the storage, processing, or re...

  13. 45 CFR 1180.59 - Records related to grant funds.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Records related to grant funds. 1180.59 Section 1180.59 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE...; and (e) Other records necessary to facilitate an effective audit. [71 FR 6372, Feb. 8, 2006] ...

  14. 38 CFR 59.124 - Inspections, audits, and reports.

    Science.gov (United States)

    2010-07-01

    ... reports. (a) A State will allow VA inspectors and auditors to conduct inspections and audits as necessary... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Inspections, audits, and reports. 59.124 Section 59.124 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS...

  15. 40 CFR 59.103 - Container labeling requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Container labeling requirements. 59.103... National Volatile Organic Compound Emission Standards for Automobile Refinish Coatings § 59.103 Container... automobile refinish coating or coating component container or package, the day, month, and year on which the...

  16. 40 CFR 59.405 - Container labeling requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Container labeling requirements. 59.405... National Volatile Organic Compound Emission Standards for Architectural Coatings § 59.405 Container... section on the coating container in which the coating is sold or distributed. (1) The date the coating was...

  17. Photosensitized oxygenation of alkenes in the presence of bisazafullerene (C59N)2 and hydroazafullerene C59HN

    International Nuclear Information System (INIS)

    Tagmatarchis, Nikos; Shinohara, Hisanori

    2001-01-01

    Bisazafullerene (C 59 N) 2 and hydroazafullerene C 59 HN photosensitize the reaction of alkenes with oxygen. 2-methyl 2-butene and α-terpinene undergo ene and Diels-Alder photooxygenation reactions, respectively, in the presence of minute amounts of azafullerenes to produce the corresponding peroxides

  18. DETECTION AND ISOLATION OF CD59 FROM HUMAN SEMINAL PLASMA

    Directory of Open Access Journals (Sweden)

    A REZAIE

    2002-06-01

    Full Text Available Introduction. CD59 is one of the complement regulatory proteins (CRPs which exert inhibitory function by blocking the formation of C5b-9 complex or Membrane Attacks complex (MAC. Regarding the therapeutic role of CD59 in treatment of pathological effects in uncontrolled activation of complements system and its efficiency to overcome the hyper-acute rejection, CD59 was suggested for maintenance of transplanted organ. In this study We determined and isolated CD59 from seminal plasma. Methods. Six normospermic sample according to WHO standards were chosen. Plasma of samples was separated and to remove the postasomes, the seminal plama was ultra centrifuged. CD59 was detected by Dot-Blot using CD59 mAb (MEM43. The molecular weight and purity of protein was detected by SOS-PAGE method follwed by Westerm Blot. Results. Protein was present in the 6.5 ml and 15ml of gel fitration fractions. Molecular weight based on marker size in these two fractions was 65 and 21KD respectively. Discussion. CD59 had previously beem purified by lysis of erythrocyte cell membrane. Because of use of detergent and preservative agents, this method decreased physiologic effects of the protein. In this study the isolation was performed from prostasome granules" without using of any detergent and preservative agents.

  19. Detection of {sup 59}Ni by accelerator mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Persson, Per; Erlandsson, Bengt; Freimann, K.; Hellborg, R.; Stenstroem, K. [Lund Univ. (Sweden). Dept. of Nuclear Physics; Larsson, Ragnar [Lund Univ. (Sweden). Chemical Engineering II; Skog, G. [Lund Univ. (Sweden). Dept. of Quaternary Geology

    1999-02-01

    The aims of this project were to develop a method to measure the amount of {sup 59}Ni in stainless steel and to determine the detection limit for this method. {sup 59}Ni is produced by neutron activation in the construction material close to the core in a nuclear reactor and it is important to know the amount of {sup 59}Ni present as it governs the classification of the waste. If the amount of {sup 59}Ni is known at different locations in relation to the core, it is also possible to refine the calculation models of the neutron flux in the reactor. Accelerator mass spectrometry, an ultra-sensitive method for measuring small concentrations of radionuclides as well as stable nuclides, has been used in this investigation to determine the concentration of {sup 59}Ni (and thereby the activity) in stainless steel. As the cobalt content in stainless steel is the main contributor to the background in a measurement of {sup 59}Ni, a method for the chemical extraction of nickel from stainless steel, including a purification step to reduce the cobalt content in the sample, has been developed. The detection limit for {sup 59}Ni has been determined to 100{+-}30 Bq per gram nickel (100{+-}30 Bq/g) with the present status of the system 14 refs, 6 figs, 3 tabs

  20. Detection of 59Ni by accelerator mass spectrometry

    International Nuclear Information System (INIS)

    Persson, Per; Erlandsson, Bengt; Freimann, K.; Hellborg, R.; Stenstroem, K.; Larsson, Ragnar; Skog, G.

    1999-02-01

    The aims of this project were to develop a method to measure the amount of 59 Ni in stainless steel and to determine the detection limit for this method. 59 Ni is produced by neutron activation in the construction material close to the core in a nuclear reactor and it is important to know the amount of 59 Ni present as it governs the classification of the waste. If the amount of 59 Ni is known at different locations in relation to the core, it is also possible to refine the calculation models of the neutron flux in the reactor. Accelerator mass spectrometry, an ultra-sensitive method for measuring small concentrations of radionuclides as well as stable nuclides, has been used in this investigation to determine the concentration of 59 Ni (and thereby the activity) in stainless steel. As the cobalt content in stainless steel is the main contributor to the background in a measurement of 59 Ni, a method for the chemical extraction of nickel from stainless steel, including a purification step to reduce the cobalt content in the sample, has been developed. The detection limit for 59 Ni has been determined to 100±30 Bq per gram nickel (100±30 Bq/g) with the present status of the system

  1. 49 CFR 570.59 - Service brake system.

    Science.gov (United States)

    2010-10-01

    ... 10,000 Pounds § 570.59 Service brake system. (a) Service brake performance. Compliance with any one of the following performance criteria will satisfy the requirements of this section. Verify that tire...

  2. 59 MDW/ST OVERVIEW BRIEFING 15 JUNE 2017

    Science.gov (United States)

    2017-06-15

    Animal Welfare Act of 1966, as amended." 59 MOW FORM 3039, 20160628 PrP~l".rihRrl hv !’i9 MDWI 41-108 PREVIOUS EDITIONS ARE OBSOLETE Page 1 of 3 Pages...and strengthen human capital , to build and maintain a strong R&A program to optimize our ability to fly, fight and win . -=~~.:~~- • 59 MOW Mission

  3. 59th Medical Wing Protection of Vulnerable Populations: Ombudsman Program

    Science.gov (United States)

    2018-04-20

    REPORT TYPE 20/04/2018 poster 4. TITLE AND SUBTITLE 59th Medical Wing Protection of Vulnerable Populations: Ombudsman Program 6. AUTHOR(S...13. SUPPLEMENTARY NOTES 2018 Annual AAHRPP Conference April 20-22, 2018 Denver, CO 14. ABSTRACT 1S. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF...59th Medical Wing Protection of Vulnerable Populations: Ombudsman Program Wayne DeutschDDS1, MPH, Michele Tavish LYN, PMP, CCRC 1 Brenda

  4. Impact of layer and substrate properties on the surface acoustic wave velocity in scandium doped aluminum nitride based SAW devices on sapphire

    Energy Technology Data Exchange (ETDEWEB)

    Gillinger, M., E-mail: manuel.gillinger@tuwien.ac.at; Knobloch, T.; Schneider, M.; Schmid, U. [Institute of Sensor and Actuator Systems, TU Wien, 1040 Vienna (Austria); Shaposhnikov, K.; Kaltenbacher, M. [Institute of Mechanics and Mechatronics, TU Wien, 1040 Vienna (Austria)

    2016-06-06

    This paper investigates the performance of surface acoustic wave (SAW) devices consisting of reactively sputter deposited scandium doped aluminum nitride (Sc{sub x}Al{sub 1-x}N) thin films as piezoelectric layers on sapphire substrates for wireless sensor or for RF-MEMS applications. To investigate the influence of piezoelectric film thickness on the device properties, samples with thickness ranging from 500 nm up to 3000 nm are fabricated. S{sub 21} measurements and simulations demonstrate that the phase velocity is predominantly influenced by the mass density of the electrode material rather than by the thickness of the piezoelectric film. Additionally, the wave propagation direction is varied by rotating the interdigital transducer structures with respect to the crystal orientation of the substrate. The phase velocity is about 2.5% higher for a-direction compared to m-direction of the sapphire substrate, which is in excellent agreement with the difference in the anisotropic Young's modulus of the substrate corresponding to these directions.

  5. The effect of scandium addition on microstructure and mechanical properties of Al–Si–Mg alloy: A multi-refinement modifier

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Cong, E-mail: xucong55555@gmail.com [Key Laboratory of Aerospace Advanced Materials and Performance of Ministry of Education, School of Material Science and Engineering, Beihang University, Beijing 100191 (China); Xiao, Wenlong, E-mail: wlxiao@buaa.edu.cn [Key Laboratory of Aerospace Advanced Materials and Performance of Ministry of Education, School of Material Science and Engineering, Beihang University, Beijing 100191 (China); Hanada, Shuji [Institute for Materials Research, Tohoku University, Sendai 980-8577 (Japan); Yamagata, Hiroshi [Center for Advanced Die Engineering and Technology, Gifu University, 1-1 Yanagido, Gifu City, Gifu 501-1193 (Japan); Ma, Chaoli [Key Laboratory of Aerospace Advanced Materials and Performance of Ministry of Education, School of Material Science and Engineering, Beihang University, Beijing 100191 (China)

    2015-12-15

    Effect of scandium (Sc) additions on the microstructure, mechanical properties and fracture behavior of Al–Si–Mg casting alloy (F357) were systematically investigated. It was found that Sc addition caused a multi-refining efficiency on the microstructure of as-cast F357 alloy, including refinement of grains and secondary dendrite arm spacing (SDAS), modification of eutectic Si and harmless disposal of β-Al{sub 5}FeSi phase. Subsequent T6 heat treatment had further induced the complete spheroidization of eutectic Si and precipitation of fine secondary Al{sub 3}Sc dispersoids in the Sc modified alloys. Thus the mechanical properties, especially the ductility, were significantly enhanced by the addition of Sc combined with the heat treatment. The highest ultimate tensile strength, yield strength and elongation were achieved in 0.8 wt.% Sc modified F357 alloy combined with T6 heat treatment. Furthermore, fractographic examinations indicated that the ductile fracture mechanism served as a dominate role in the modified alloys due to the formation of fine, deep and uniformly distributed dimples. - Highlights: • Detailed characterization of the multi-refining microstructure of Sc modified F357 alloy was performed. • The multi-refinement was proposed to refine grain and SDAS, modify eutectic Si and β-phase. • Sc modifier combined with T6 treatment is effective in improving tensile properties. • Modification of eutectic Si in F357 alloy with Sc is consistent with the IIT mechanism.

  6. Serum sample levels of bromine, iron, scandium and zinc in preschool children of Atayal and Bunun aborigines living in central Taiwan

    International Nuclear Information System (INIS)

    Chien-Yi Chen; Ding-Bang Lin; Yuan-Yaw Wei

    2006-01-01

    This study determined bromine, iron, scandium and zinc serum levels in Taiwanese aboriginal preschool children living in remote mountainous areas to increase the understanding of the social, cultural, nutrient and ethnic background of the Taiwanese children. Seventy-three serum samples were taken from two ethnic groups of preschool children, Atayal aborigines (AAPC) and Bunun aborigines (BAPC). Sera of these children were freeze dried. Trace elements in sera were identified by instrumental neutron activation analysis (INAA). The accuracy and precision of INAA was evaluated using certified reference materials: Tomato Leaves (NIST-SRM 1570a) and Lichen (IAEA-336). Statistical analysis identified several different patterns for ethnic groups, gender and age via the two-tailed Student's t-test. Analytical results showed that the ranges of Br, Fe, Sc and Zn in sera were somewhat wide. The Zn serum levels (p < 0.05) and Br serum levels (p < 0.01) in the AAPC were significantly lower than those in the BAPC. However, there were no significant differences in Fe or Sc serum levels between the two groups. Analytical results were compared to published data for different counties. This study is the first investigating trace elements in Taiwanese aborigines and can be used to establish a much-needed serum element database. (author)

  7. Comparative microstructure and electrical property studies of lead scandium tantalate thin films as prepared by LDCVD, sol-gel and sputtering techniques

    International Nuclear Information System (INIS)

    Huang, Z; Donohue, P P; Zhang, Q; Williams, D J; Anthony, C J; Whatmore, R W; Todd, M A

    2003-01-01

    Lead scandium tantalate (PST) thin films for uncooled infrared (IR) detector applications have been deposited by liquid delivery chemical vapour deposition (LDCVD), sputtering and sol-gel techniques. The sol-gel and sputtered films were deposited at low temperature into a non-ferroelectric phase with the required perovskite structure being formed using a high temperature rapid thermal anneal (RTA). In contrast to this, the LDCVD films were deposited at high temperature directly into the perovskite phase but were found to still require a high temperature RTA step to optimize their merit for IR detection. Detailed structural and electrical characterization of the PST films deposited by these different methods have revealed that there is no simple relationship between microstructure and electrical properties. The sol-gel and LDCVD techniques produce thin films with excellent microstructures, as determined by x-ray diffraction analysis and transmission electron microscopy, but inferior electrical properties and relatively low merit figures. By contrast, the sputtered and then rapid thermal annealed films have inferior microstructures, characterized by extensive voiding, but excellent electrical properties and high merit figures

  8. Comparative evaluation of surface topography of tooth prepared using erbium, chromium: Yttrium, scandium, gallium, garnet laser and bur and its clinical implications.

    Science.gov (United States)

    Verma, Mahesh; Kumari, Pooja; Gupta, Rekha; Gill, Shubhra; Gupta, Ankur

    2015-01-01

    Erbium, chromium: Yttrium, scandium, gallium, garnet (Er, Cr: YSGG) laser has been successfully used in the ablation of dental hard and soft tissues. It has been reported that this system is also useful for preparing tooth surfaces and etching, but no consensus exist in the literature regarding the advantage of lasers over conventional tooth preparation technique. Labial surfaces of 25 extracted human maxillary central incisors were divided into two halves. Right half was prepared with diamond bur and left half with Er, Cr; YSGG laser and a reduction of 0.3-0.5 mm was carried out. Topography of prepared surfaces of five teeth were examined under scanning electron microscope (SEM). The remaining samples were divided into 4 groups of 10 specimens each based on the surface treatment received: One group was acid etched and other was nonetched. Composite resin cylinders were bonded on prepared surfaces and shear bond strength was assessed using a universal testing machine. The SEM observation revealed that the laser prepared surfaces were clean, highly irregular and devoid of a smear layer. Bur prepared surfaces were relatively smooth but covered with smear layer. Highest bond strength was shown by laser prepared acid etched group, followed by bur prepared the acid etched group. The bur prepared nonacid etched group showed least bond strength. Er, Cr: YSGG laser can be used for preparing tooth and bond strength value achieved by laser preparation alone without surface treatment procedure lies in the range of clinical acceptability.

  9. Aluminum-Scandium Alloys: Material Characterization, Friction Stir Welding, and Compatibility With Hydrogen Peroxide (MSFC Center Director's Discretionary Fund Final Report, Proj. No. 04-14)

    Science.gov (United States)

    Lee, J. A.; Chen, P. S.

    2004-01-01

    This Technical Memorandum describes the development of several high-strength aluminum (Al) alloys that are compatible with hydrogen peroxide (H2O2) propellant for NASA Hypersonic-X (Hyper-X) vehicles fuel tanks and structures. The yield strengths for some of these Al-magnesium-based alloys are more than 3 times stronger than the conventional 5254-H112 Al alloy, while maintaining excellent H2O2 compatibility similar to class 1 5254 alloy. The alloy development strategy is to add scandium, zirconium, and other transitional metals with unique electrochemical properties, which will not act as catalysts, to decompose the highly concentrated 90 percent H2O2. Test coupons are machined from sheet metals for H2O2 long-term exposure testing and mechanical properties testing. In addition, the ability to weld the new alloys using friction stir welding has also been explored. The new high-strength alloys could represent an enabling material technology for Hyper-X vehicles, where flight weight reduction is a critical requirement.

  10. Investigation of concentration-dependence of thermodynamic properties of lanthanum, yttrium, scandium and terbium in eutectic LiCl-KCl molten salt

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yafei; Zhou, Wentao; Zhang, Jinsuo, E-mail: zhang.3558@osu.edu

    2016-09-15

    Thermodynamic properties of rare earth metals in LiCl-KCl molten salt electrolyte are crucial to the development of electrochemical separation for the treatment of used nuclear fuels. In the present study, activity coefficient, apparent potential, and diffusion coefficient of lanthanum, yttrium, scandium, and terbium in the molten salt (58 at% LiCl and 42 at% KCl) were calculated by the method of molecular dynamics simulation up to a concentration around 3 at% at temperatures of 723 K and 773 K. It was found that the activity coefficient and the apparent potential increase with the species concentration while diffusion coefficient shows a trend of increase followed by decrease. The calculated results were validated by available measurement data of dilution cases. This research extends the range of data to a wide component and would provide further insight to the pyroprocessing design and safeguards. - Highlights: • Investigation of activity coefficient, apparent potential and diffusion coefficient at different concentrations. • MD simulation was studied for the calculation of thermodynamic properties of rare earth elements in molten salt. • The present study is a pioneering work focusing on the concentration dependence of thermodynamic properties.

  11. Iron-59 absorption from soy hulls: intrinsic vs extrinsic labeling

    International Nuclear Information System (INIS)

    Lykken, G.I.; Mahalko, J.R.; Nielsen, E.J.; Dintzis, F.R.

    1986-01-01

    As part of an evaluation of the validity of the extrinsic labeling technique for measuring iron absorption, absorption from soy hulls extrinsically labeled ( 59 Fe added to bread dough) was compared with that from soy hulls intrinsically labeled ( 59 Fe incorporated into the soy plant during growth). Century soybeans were grown in a greenhouse. After pods had formed and were filling, each plant was stem injected twice, at 3 day intervals, with 22 μCi 59 Fe as FeCl 2 in 25 μl of 0.5 M HCl solution. After the plants had senesced, the soybeans were harvested, dried, shelled and the hulls removed. Standard meals containing 3.5 mg Fe/meal and up to 0.06 μCi 59 Fe in a soy hull bun were fed on 2 consecutive days to free-living volunteers in a crossover design. Absorption of 59 Fe was greater from intrinsically labeled soy hulls than from extrinsically labeled soy hulls, 20 +/- 20% vs 15 +/- 11% (n=14, p > 0.05 by paired t-test). Apparent absorption ranged from 1.3% to 77% from intrinsically labeled soy hulls and .5% to 29% from extrinsically labeled soy hulls with the highest absorption occurring in persons with low serum ferritin (S.F. < 8 ng/ml). These findings provide additional evidence that the extrinsic labeling method is a valid measure of iron bioavailability to humans

  12. New and superior adrenal scanning agent, NP-59

    International Nuclear Information System (INIS)

    Sarkar, S.D.; Beierwaltes, W.H.; Ice, R.D.; Basmadjian, G.P.; Hertzel, K.R.; Kennedy, W.P.; Mason, M.M.

    1975-01-01

    The first synthesis of 131 I-19-iodocholesterol had a 10 to 25 percent radiochemical impurity that was not iodide ion. This impurity has been identified as 6β- 131 I-iodomethyl-19-nor cholest-5(10)-en-3β-ol (NP-59) and has been synthesized. Tissue distribution studies with 131 I-NP-59 in rats and dogs revealed a higher adrenal uptake and adrenal-to-tissue ratios compared to 131 I 19-iodocholesterol, probably less in vivo deiodination, and superior adrenal images. A high uptake was seen in the adrenal medulla in addition to that in the cortex. Iodine-131-NP-59 is being evaluated for the early detection of adrenal--cortical disorders and as a potential scanning agent for detecting structural abnormalities of the adrenal medulla

  13. Adrenal scintiscanning with NP-59: a new radioiodinated cholesterol agent

    International Nuclear Information System (INIS)

    Miles, J.M.; Wahner, H.W.; Carpenter, P.C.; Salassa, R.M.; Northcutt, R.C.

    1979-01-01

    Adrenal imaging in the past has been limited in its clinical application by the long interval between administration of dose and visualization of adrenal glands. We review our experience with the use of a newer labeling agent, NP-59, in 29 patients with various adrenal disorders and in 4 normal subjects. With this agent, identification of adrenal lesions is possible with a high degree of accuracy, and diagnostic information is usually available within 48 hrs. NP-59 is particularly useful in evaluating primary aldosteronism and selected cases of Cushing's syndrome

  14. On new ternary equiatomic scandium transition metal aluminum compounds ScTAl with T = Cr, Ru, Ag, Re, Pt, and Au

    Energy Technology Data Exchange (ETDEWEB)

    Radzieowski, Mathis; Janka, Oliver [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie; Benndorf, Christopher [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie; Muenster Univ. (Germany). Inst. fuer Physikalische Chemie; Haverkamp, Sandra [Muenster Univ. (Germany). Inst. fuer Physikalische Chemie; Eckert, Hellmut [Muenster Univ. (Germany). Inst. fuer Physikalische Chemie; University of Sao Paulo, Sao Carlos, SP (Brazil). Inst. of Physics

    2016-08-01

    The new equiatomic scandium transition metal aluminides ScTAl for T = Cr, Ru, Ag, Re, Pt, and Au were obtained by arc-melting of the elements followed by subsequent annealing for crystal growth. The samples were studied by powder and single crystal X-ray diffraction. The structures of three compounds were refined from single crystal X-ray diffractometer data: ScCrAl, MgZn{sub 2} type, P6{sub 3}/mmc, a = 525.77(3), c = 858.68(5) pm, R{sub 1} = 0.0188, wR{sub 2} = 0.0485, 204 F{sup 2} values, 13 variables, ScPtAl, TiNiSi type, Pnma, a = 642.83(4), b = 428.96(2), c = 754.54(5) pm, R{sub 1} = 0.0326, wR{sub 2} = 0.0458, 448 F{sup 2} values, 20 variables and ScAuAl, HfRhSn type, P anti 62c, a = 722.88(4), c = 724.15(4) pm, R{sub 1} = 0.0316, wR{sub 2} = 0.0653, 512 F{sup 2} values, 18 variables. Phase pure samples of all compounds were furthermore investigated by magnetic susceptibility measurements, and Pauli-paramagnetism but no superconductivity was observed down to 2.1 K for all of them. The local structural features and disordering phenomena have been characterized by {sup 27}Al and {sup 45}Sc magic angle spinning (MAS) and static NMR spectroscopic investigations.

  15. Comparative study of the shear bond strength of composite resin bonded to enamel treated with acid etchant and erbium, chromium: Yttrium, scandium, gallium, garnet laser

    Directory of Open Access Journals (Sweden)

    Adel Sulaiman Alagl

    2016-01-01

    Full Text Available Aim: The purpose of this investigation is in vitro comparison of the shear bond strength (SBS of composite resin bonded to enamel pretreated with an acid etchant against enamel etched with erbium, chromium: yttrium, scandium, gallium, garnet (Er, Cr:YSGG laser. Materials and Methods: Sixty premolars were sectioned mesiodistally and these 120 specimens were separated into two groups of 60 each (Groups A and B. In Group A (buccal surfaces, enamel surface was etched using 37% phosphoric acid for 15 s. In Group B (lingual surfaces, enamel was laser-etched at 2W for 10 s by Er, Cr:YSGG laser operational at 2780 nm with pulse duration of 140 μs and a frequency of 20 Hz. After application of bonding agent on all test samples, a transparent plastic cylinder of 1.5 mm × 3 mm was loaded with composite and bonded by light curing for 20 s. All the samples were subjected to SBS analysis using Instron Universal testing machine. Failure modes were observed under light microscope and grouped as adhesive, cohesive, and mixed. Failure mode distributions were compared using the Chi-square test. Results: SBS values obtained for acid-etched enamel were in the range of 7.12–28.36 megapascals (MPa and for laser-etched enamel were in the range of 6.23–23.35 MPa. Mean SBS for acid-etched enamel was 15.77 ± 4.38 MPa, which was considerably greater (P < 0.01 than laser-etched enamel 11.24 ± 3.76 MPa. The Chi-square test revealed that the groups showed no statistically significant differences in bond failure modes. Conclusions: We concluded that the mean SBS of composite with acid etching is significantly higher as compared to Er, Cr: YSGG (operated at 2W for 10 s laser-etched enamel.

  16. 42 CFR 410.59 - Outpatient occupational therapy services: Conditions.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Outpatient occupational therapy services... Other Health Services § 410.59 Outpatient occupational therapy services: Conditions. (a) Basic rule... occupational therapy services only if they are furnished by an individual meeting the qualifications in part...

  17. 42 CFR 59a.7 - Other HHS regulations that apply.

    Science.gov (United States)

    2010-10-01

    ... assistance through the Department of Health and Human Services—effectuation of title VI of the Civil Rights....7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL LIBRARY OF MEDICINE GRANTS Grants for Establishing, Expanding, and Improving Basic Resources § 59a.7 Other...

  18. Sample Set (SE): SE59 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available idopsis thaliana (Arabidopsis). However, the behavior of flavonoids during drough...t stress is still not well documented. Herein we investigated the time-series alternation of flavonoids in t...vonoids, a class of specialized metabolites, including flavonols and anthocyanins w...SE59 Alternation of flavonoid accumulation under drought stress in Arabidopsis thaliana We reported that fla

  19. 32 CFR 516.59 - Duties and procedures.

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    2010-07-01

    ... PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.59 Duties and procedures... agencies; contracting officers; inspectors general of the executive branch; correspondence from the public... indications of fraud or corruption relating to Army contracts or Army administered contracts are reported...

  20. 49 CFR 213.59 - Elevation of curved track; runoff.

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    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Elevation of curved track; runoff. 213.59 Section... track; runoff. (a) If a curve is elevated, the full elevation shall be provided throughout the curve, unless physical conditions do not permit. If elevation runoff occurs in a curve, the actual minimum...

  1. 42 CFR 59.206 - Evaluation and grant award.

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    2010-10-01

    ...) Development of a capability within family planning service projects to provide pre- and in-service training to... and health services personnel; (iii) Improvement in the utilization and career development of... PLANNING SERVICES Grants for Family Planning Service Training § 59.206 Evaluation and grant award. (a...

  2. 34 CFR 674.59 - Cancellation for military service.

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    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Cancellation for military service. 674.59 Section 674... Cancellation for military service. (a) Cancellation on a Defense loan. (1) An institution must cancel up to 50... cancellation rate is 121/2 percent of the original loan principal, plus the interest on the unpaid balance...

  3. 40 CFR 59.412 - Incorporations by reference.

    Science.gov (United States)

    2010-07-01

    ... Test Method for Chemical Resistance of Coatings Used in Light-Water Nuclear Power Plants, incorporation by reference approved for § 59.401, Nuclear coating. (5) ASTM Method D 4082-89, Standard Test Method for Effects of Gamma Radiation on Coatings for Use in Light-Water Nuclear Power Plants, incorporation...

  4. 21 CFR 7.59 - General industry guidance.

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    2010-04-01

    ... Responsibilities § 7.59 General industry guidance. A recall can be disruptive of a firm's operation and business... and maintain a current written contingency plan for use in initiating and effecting a recall in... such product distribution records as are necessary to facilitate location of products that are being...

  5. 17 CFR 201.59 - Payment of award.

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    2010-04-01

    ... as authorized by law, unless judicial review of the award has been sought by the applicant. [54 FR... Regulations Pertaining to the Equal Access to Justice Act § 201.59 Payment of award. An applicant seeking... decision granting the award, accompanied by a sworn statement that the applicant will not seek review of...

  6. 38 CFR 59.100 - Payment of grant award.

    Science.gov (United States)

    2010-07-01

    ... instrumentality. Such amount shall be paid by way of reimbursement, and in such installments consistent with the... State representative, and must submit to VA a completed VA Form 10-0388-13 (this form is available on the internet Web site provided in § 59.170). The equipment list and the completed VA Form 10-0388-13...

  7. Solvent extraction of anionic chelate complexes of lanthanum(III), europium(III), lutetium(III), scandium(III), and indium(III) with 2-thenoyltrifluoroacetone as ion-pairs with tetrabutylammonium ions

    International Nuclear Information System (INIS)

    Noro, Junji; Sekine, Tatsuya.

    1992-01-01

    The solvent extraction of lanthanum(III), europium(III), lutetium(III), scandium(III), and indium(III) in 0.1 mol dm -3 sodium nitrate solutions with 2-thenoyltrifluoroacetone (Htta) in the absence and presence of tetrabutylammonium ions (tba + ) into carbon tetrachloride was measured. The extraction of lanthanum(III), europium(III), and lutetium(III) was greatly enhanced by the addition of tba + ; this could be explained in terms of the extraction of a ternary complex, M(tta) 4 - tba + . However, the extractions of scandium(III) and indium(III) were nearly the same when tba + was added. The data were treated on the basis of the formation equilibrium of the ternary complex from the neutral chelate, M(tta) 3 , with the extracted ion-pairs of the reagents, tta - tba + , in the organic phase. It was concluded that the degree of association of M(tta) 3 with the ion-pair, tta - tba + , is greater in the order La(tta) 3 ≅ Eu(tta) 3 > Lu(tta) 3 , or that the stability of the ternary complex in the organic phase is higher in the order La(tta) 4 - tba + ≅ Eu(tta) 4 - tba + > Lu(tta) 4 - tba + . This is similar to those of adduct metal chelates of Htta with tributylphosphate (TBP) in synergistic extraction systems. (author)

  8. The trigger and DAQ systems of the NA59 experiment

    CERN Document Server

    Ünel, Gokhan; Ballestrero, Sergio

    2004-01-01

    The NA59 experiment on the CERN SPS-H2 beam-line took data during the summers of 1999 and 2000 to perform intercalibration studies of polarization measurement and to test the use of an aligned crystal as a quarter-wave plate. The analysis revealed a proof of concept for the birefringence property of aligned crystals for photons in the 30-170 GeV energy range. The 90-m-long detector for this fixed target experiment had two independent readout schemes: one for more than 120 time-to-digital and analog-to-digital converter channels to obtain tracking and energy information; and another for the readout of the silicon strip detectors to improve vertex resolution. The readout electronics of the Na59 experiment was based on VMEbus and CAMAC systems. Novel data acquisition and online monitoring software were written to work on the commodity hardware (PCs) running mainly the Linux operating system. 21 Refs.

  9. STS-59 crewmembers in training for onboard Earth observations

    Science.gov (United States)

    1993-01-01

    The six astronauts in training for the STS-59 mission are shown onboard Earth observations tips by Justin Wilkinson (standing, foreground) of the Space Shuttle Earth Observations Project (SSEOP) group. Astronaut Sidney M. Gutierrez, mission commander, is at center on the left side of the table. Others, left to right, are Astronauts Kevin P. Chilton, pilot; Jerome (Jay) Apt and Michael R.U. (Rich) Clifford, both mission specialists; Linda M. Godwin, payload commander; and Thomas D. Jones, mission specialist.

  10. TMEM59 potentiates Wnt signaling by promoting signalosome formation.

    Science.gov (United States)

    Gerlach, Jan P; Jordens, Ingrid; Tauriello, Daniele V F; van 't Land-Kuper, Ineke; Bugter, Jeroen M; Noordstra, Ivar; van der Kooij, Johanneke; Low, Teck Y; Pimentel-Muiños, Felipe X; Xanthakis, Despina; Fenderico, Nicola; Rabouille, Catherine; Heck, Albert J R; Egan, David A; Maurice, Madelon M

    2018-04-09

    Wnt/β-catenin signaling controls development and adult tissue homeostasis by regulating cell proliferation and cell fate decisions. Wnt binding to its receptors Frizzled (FZD) and low-density lipoprotein-related 6 (LRP6) at the cell surface initiates a signaling cascade that leads to the transcription of Wnt target genes. Upon Wnt binding, the receptors assemble into large complexes called signalosomes that provide a platform for interactions with downstream effector proteins. The molecular basis of signalosome formation and regulation remains elusive, largely due to the lack of tools to analyze its endogenous components. Here, we use internally tagged Wnt3a proteins to isolate and characterize activated, endogenous Wnt receptor complexes by mass spectrometry-based proteomics. We identify the single-span membrane protein TMEM59 as an interactor of FZD and LRP6 and a positive regulator of Wnt signaling. Mechanistically, TMEM59 promotes the formation of multimeric Wnt-FZD assemblies via intramembrane interactions. Subsequently, these Wnt-FZD-TMEM59 clusters merge with LRP6 to form mature Wnt signalosomes. We conclude that the assembly of multiprotein Wnt signalosomes proceeds along well-ordered steps that involve regulated intramembrane interactions. Copyright © 2018 the Author(s). Published by PNAS.

  11. Erythrokinetics examination using 59Fe and 51Cr isotopes

    International Nuclear Information System (INIS)

    Mistrik, M.; Klinda, F.; Geso, L.; Lipsic, T.

    1987-01-01

    The results are discussed of 55 case studies of various hematological diseases in which 59 Fe was used as a tracer in studying iron kinetics, simultaneously with 51 Cr as a tracer in studying erythrocyte survival and the localization of erythrocyte destruction. The values of iron metabolism are graphically presented, while erythropoiesis data is tabulated. The method was especially beneficial in conditions that could not easily be diagnosed using laboratory techniques. They included osteomyelofibrosis, polycythemia vera, aplastic anemia, and the myelodysplastic syndrome. The method allows quantitative assessment of erythropoiesis, thus facilitating differential diagnosis in clinical practice. (L.O.). 3 figs., 1 tab., 22 refs

  12. Multilevel resonance analysis of sup 59 Co neutron transmission measurements

    Energy Technology Data Exchange (ETDEWEB)

    De Saussure, G.; Larson, N.M.; Harvey, J.A.; Hill, N.W. (Oak Ridge National Lab., TN (United States))

    1992-07-01

    Large discrepancies exist between the recent high-resolution neutron transmission data of {sup 59}Co measured at the Oak Ridge Electron Linear Accelerator (ORELA) and transmissions computed from the resolved resonance parameters of the nuclear data collection ENDF/B-VI. In order to provide new resonance parameters consistent with these data, the transmission measurements have been analyzed with the computer code SAMMY in the energy range 200 eV to 100 keV. The resonance parameters reported in this paper provide an accurate total cross section from 10{sup -5} eV to 100 keV and correctly reproduce the thermal capture cross section. Thermal cross-section values and related quantities are also reviewed here. (author).

  13. Young Cluster Berkeley 59: Properties, Evolution, and Star Formation

    Science.gov (United States)

    Panwar, Neelam; Pandey, A. K.; Samal, Manash R.; Battinelli, Paolo; Ogura, K.; Ojha, D. K.; Chen, W. P.; Singh, H. P.

    2018-01-01

    Berkeley 59 is a nearby (∼1 kpc) young cluster associated with the Sh2-171 H II region. We present deep optical observations of the central ∼2.5 × 2.5 pc2 area of the cluster, obtained with the 3.58 m Telescopio Nazionale Galileo. The V/(V–I) color–magnitude diagram manifests a clear pre-main-sequence (PMS) population down to ∼0.2 M ⊙. Using the near-infrared and optical colors of the low-mass PMS members, we derive a global extinction of A V = 4 mag and a mean age of ∼1.8 Myr, respectively, for the cluster. We constructed the initial mass function and found that its global slopes in the mass ranges of 0.2–28 M ⊙ and 0.2–1.5 M ⊙ are ‑1.33 and ‑1.23, respectively, in good agreement with the Salpeter value in the solar neighborhood. We looked for the radial variation of the mass function and found that the slope is flatter in the inner region than in the outer region, indicating mass segregation. The dynamical status of the cluster suggests that the mass segregation is likely primordial. The age distribution of the PMS sources reveals that the younger sources appear to concentrate close to the inner region compared to the outer region of the cluster, a phenomenon possibly linked to the time evolution of star-forming clouds. Within the observed area, we derive a total mass of ∼103 M ⊙ for the cluster. Comparing the properties of Berkeley 59 with other young clusters, we suggest it resembles more closely the Trapezium cluster.

  14. Binary and ternary chelates of scandium (III), Yttrium (III) and lanthanum (III) with ethyleneglycol-bis(. beta. -aminoethylether)-tetraacetic acid as primary and substituted salicylic acids as secondary ligands

    Energy Technology Data Exchange (ETDEWEB)

    Pandey, A K; Chandra, M; Agarwala, B V; Dey, A K [Allahabad Univ. (India). Chemical Labs.

    1980-01-01

    Formation constants of binary and ternary complexes of the systems of the type: M-L and M-egta-L (M = scandium(III), yttrium(III) and lanthanum(III), egta = ethylene glycol-bis(..beta..-aminoethylether)-tetra acetic acid, L = o-cresotic acid (o-ca), m-cresotic acid (m-ca), 5-chlorosalicyclic acid(csa), and 3,5-dibromosalicylic acid (dbsa)) have been determined pH-metrically at 25deg and ..mu.. = 0.1M (KNO/sub 3/) in 50% (v/v) aqueous-ethanol medium. The order of stabilities of ternary complexes has been compared with those of corresponding binary complexes, and results discussed on the basis of coulombic interactions.

  15. A novel boron-rich quaternary scandium borocarbosilicide Sc3.67-xB41.4-y-zC0.67+zSi0.33-w

    International Nuclear Information System (INIS)

    Tanaka, Takaho; Yamamoto, Akiji; Sato, Akira

    2004-01-01

    A novel quaternary scandium borocarbosilicide Sc 3.67-x B 41.4-y-z C 0.67+z Si 0.33-w was found. Single crystallites were obtained as an intergrowth phase in the float-zoned single crystal of Sc 0.83-x B 10.0-y C 0.17+y Si 0.083-z that has a face-centered cubic crystal structure. Single crystal structure analysis revealed that the compound has a hexagonal structure with lattice constants a = b = 1.43055(8) nm and c = 2.37477(13) nm and space group P6-barm2 (No. 187). The crystal composition calculated from the structure analysis for the crystal with x = 0.52, y = 1.42, z = 1.17, and w = 0.02 was ScB 12.3 C 0.58 Si 0.10 and that agreed rather well with the composition of ScB 11.5 C 0.61 Si 0.04 measured by EPMA. In the crystal structure that is a new structure type of boron-rich borides, there are 79 structurally independent atomic sites, 69 boron and/or carbon sites, two silicon sites and eight scandium sites. Boron and carbon form seven structurally independent B 12 icosahedra, one B 9 polyhedron, one B 10 polyhedron, one irregularly shaped B 16 polyhedron in which only 10.7 boron atoms are available because of partial occupancies and 10 bridging sites. All polyhedron units and bridging site atoms interconnect each other forming a three-dimensional boron framework structure. Sc atoms reside in the open spaces in the boron framework structure

  16. The efficacy of radiotherapy for 59 patients with vertebral hemangioma

    International Nuclear Information System (INIS)

    Qian Liting; Liu Xinfan; Li Yexiong; Yu Zihao; Yin Weibo

    2004-01-01

    Objective: To investigate the indication, total dose and efficacy of radiotherapy for vertebral hemangiomas. Methods: Between 1967 and 2000, 59 patients (36 female, 23 male) with vertebral hemangioma were treated with deep X-ray, electron beam, 60 Co or 6-8MV X-ray with a total dose ranging from 28 to 90 Gy and a median of 40 Gy. Results: Of the 54 evaluable cases, the overall response rate was 87.0%. The response rates were 90.2% and 83.3%, respectively, for patients treated with 34-40 Gy and more than 40 Gy (χ 2 =0.41, P=0.608). Among the 9 patients with paraplegic patients, 4 achieved complete response, 4 partial response, and only one showed no response to the treatment. Conclusions: Radiotherapy is effective and safe for symptomatic vertebral hemangioma, on condition of a suitable total dose range of 30 to 40 Gy. Patients with asymptomatic or minor symptomatic lesion should be watched and followed rather than giving immediate treatment. Radiation therapy shows slow and delayed improvement in vertebral hemangioma and the symptoms are gradually relieved or disappear in three months to seven years with a median interval of 1.5 years, even though diagnostic images show no or only minor changes after treatment

  17. The Neuron-Specific Protein TMEM59L Mediates Oxidative Stress-Induced Cell Death.

    Science.gov (United States)

    Zheng, Qiuyang; Zheng, Xiaoyuan; Zhang, Lishan; Luo, Hong; Qian, Lingzhi; Fu, Xing; Liu, Yiqian; Gao, Yuehong; Niu, Mengxi; Meng, Jian; Zhang, Muxian; Bu, Guojun; Xu, Huaxi; Zhang, Yun-Wu

    2017-08-01

    TMEM59L is a newly identified brain-specific membrane-anchored protein with unknown functions. Herein we found that both TMEM59L and its homolog, TMEM59, are localized in Golgi and endosomes. However, in contrast to a ubiquitous and relatively stable temporal expression of TMEM59, TMEM59L expression was limited in neurons and increased during development. We also found that both TMEM59L and TMEM59 interacted with ATG5 and ATG16L1, and that overexpression of them triggered cell autophagy. However, overexpression of TMEM59L induced intrinsic caspase-dependent apoptosis more dramatically than TMEM59. In addition, downregulation of TMEM59L prevented neuronal cell death and caspase-3 activation caused by hydrogen peroxide insults and reduced the lipidation of LC3B. Finally, we found that AAV-mediated knockdown of TMEM59L in mice significantly ameliorated caspase-3 activation, increased mouse duration in the open arm during elevated plus maze test, reduced mouse immobility time during forced swim test, and enhanced mouse memory during Y-maze and Morris water maze tests. Together, our study indicates that TMEM59L is a pro-apoptotic neuronal protein involved in animal behaviors such as anxiety, depression, and memory, and that TMEM59L downregulation protects neurons against oxidative stress.

  18. Variations in absorbed doses from 59Fe in different diseases

    International Nuclear Information System (INIS)

    Roth, P.; Werner, E.; Henrichs, K.; Elsasser, U.; Kaul, A.

    1986-01-01

    The biokinetics of radiopharmaceuticals administered in vivo may vary considerably with changes in organ functions. They studied the variations in absorbed doses from 59 Fe in 207 patients with different diseases, in whom ferrokinetic investigations were performed for diagnostic purposes. Radiation doses to the bone marrow were highest in patients with deserythropoietic anemias (mean 38 nSv/Bq, range 19 - 57 nSv/Bq) and in hemolytic anemias (mean 21 nSv/Bq, range 7 - 35 nSv/Bq), whereas lower and rather constant values were found in other diseases (mean values between 9 and 13 nSv/Bq). The highest organ doses, the greatest differences with respect to diagnosis and also the largest variations within each group of patients were found for liver and spleen (e. g. in aplastic anemia; liver: 66 nSv/Bq, range 29 - 104 nSv/Bq; spleen: 57 nSv/Bq, range 34 - 98 nSv/Bq. In iron deficiency; liver: 13 nSv/Bq range 12 - 14 nSv/q; spleen: 19 nSv/Bq, range 18 - 20 nSv/Bq). Lower organ doses and smaller variations within and between the groups of patients were found for the gonads (means 3 - 7 nSv/Bq), the kidneys (means 10 - 13 nSv/Bq), the bone (means 4 - 7 nSv/Bq), the lung (means 8 - 12 nSv/Bq), and the total body (means 6 - 8 nSv/Bq). In patients with chronic bleeding absorbed doses decrease concomitantly to the extent of blood loss. The D/sub E/ is not markedly affected by the variations in organ doses but is fairly constant for different diseases. 16 references, 1 figure, 3 tables

  19. Tratamento cirúrgico dos insulinomas -- estudo de 59 casos Surgical treatment of insulinoma. Study of 59 cases

    Directory of Open Access Journals (Sweden)

    M.C.C. Machado

    1998-06-01

    Full Text Available Após a confirmação clínica e laboratorial de hiperinsulinismo, o principal problema consiste na localização precisa da lesão no parênquima pancreático, propiciando tratamento cirúrgico adequado. OBJETIVO: Analisar os métodos utilizados para o diagnóstico e localização pré e intra-operatório dos insulinomas, bem como as técnicas e os resultados do tratamento cirúrgico. MÉTODOS: Foram estudados 59 casos consecutivos de insulinoma submetidos a intervenção cirúrgica. Cada um dos métodos utilizados para a localização pré-operatória dessas lesões foi avaliado quanto à sua eficiência em confronto com os achados intra-operatórios. A palpação do pâncreas, isoladamente ou associada à ultra-sonografia intra-operatória, como métodos de localização dos insulinomas, foi também estudada. Os tipos de intervenção cirúrgica foram analisados quanto aos seus resultados imediatos e tardios. RESULTADOS: Dos 59 insulinomas, 55 eram benignos e quatro, malignos. Dos métodos utilizados para a localização pré-operatória, a ultra-sonografia foi eficiente em 28,1% dos casos, a tomografia computadorizada em 25%, a ultra-sonografia endoscópica em 27,2%, a arteriografia seletiva em 54,1% e a colheita de amostras de sangue portal para dosagem de insulina em 94,4% dos casos. A palpação bidigital, durante a intervenção cirúrgica, localizou as lesões em 54/55 casos (98,2%. A ultra-sonografia intra-operatória foi decisiva em apenas um caso. Cinco doentes apresentavam neoplasia endócrina múltipla tipo I e em todos as lesões pancreáticas eram múltiplas. Foram efetuadas 29 enucleações e 32 ressecções pancreáticas nos doentes com lesões benignas. Os doentes com lesões malignas foram submetidos a ressecções pancreáticas e quimioterapia. Não houve mortalidade, porém observaram-se complicações (fístulas em 29/59 casos. Os resultados foram bons em 98,1% dos doentes com lesões benignas. Apenas um dos doentes com

  20. Iron-59 transfer across the placenta at late pregnancy in rat

    International Nuclear Information System (INIS)

    Zylicz, E.

    1976-01-01

    The transfer of 59 Fe from mother to foetus in relation to the time of gestation was examined 24 hours after injecting 5 μCi of 59 Fe-citrate. The radioactivity of foetuses, placentae and some mother organs between 15th and 21st days of gestation was determined. A striking daily foetal 59 Fe increment with a concomitant decrease of 59 Fe level in maternalorgans was observed from 16th day of pregnancy. (author)

  1. Evaluation of neutron monitor cross sections for 59Co(n,x)56,57,58Co, 52,54,56Mn, 59Fe reactions

    International Nuclear Information System (INIS)

    Yu Baosheng; Shen Qingbiao; Cai Dunjiu

    1996-01-01

    The neutron monitor cross sections for 59 Co(n,x) 56,57,58 Co, 52,54,56 Mn, 59 Fe reactions were evaluated based on recent experimental data and theoretical calculations from threshold energy to 100 MeV. (8 figs.)

  2. 40 CFR 81.59 - Cumberland-Keyser Interstate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... Quality Control Region. 81.59 Section 81.59 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.59 Cumberland-Keyser Interstate Air Quality Control Region. The Cumberland-Keyser Interstate Air Quality Control Region (Maryland-West Virginia) has been revised to consist...

  3. 7 CFR 2.59 - Deputy Under Secretaries for Natural Resources and Environment.

    Science.gov (United States)

    2010-01-01

    ... Environment. 2.59 Section 2.59 Agriculture Office of the Secretary of Agriculture DELEGATIONS OF AUTHORITY BY... Under Secretary for Natural Resources and Environment § 2.59 Deputy Under Secretaries for Natural Resources and Environment. Pursuant to § 2.20(a), subject to reservations in § 2.20(b), and subject to...

  4. 46 CFR 160.151-59 - Operating instructions and information for the ship's training manual.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Operating instructions and information for the ship's training manual. 160.151-59 Section 160.151-59 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Inflatable Liferafts (SOLAS) § 160.151-59...

  5. 19 CFR 210.59 - Responses to the motion and the complaint.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Responses to the motion and the complaint. 210.59 Section 210.59 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE ADJUDICATION AND ENFORCEMENT Temporary Relief § 210.59 Responses to the motion and...

  6. 49 CFR 1242.59 - Train inspection and lubrication (account XX-51-62).

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Train inspection and lubrication (account XX-51-62). 1242.59 Section 1242.59 Transportation Other Regulations Relating to Transportation (Continued) SURFACE...-Transportation § 1242.59 Train inspection and lubrication (account XX-51-62). Separate common expenses on basis...

  7. 42 CFR 59.9 - For what purpose may grant funds be used?

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false For what purpose may grant funds be used? 59.9 Section 59.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Project Grants for Family Planning Services § 59.9 For what purpose may...

  8. 40 CFR 59.621 - Who may apply for a certificate of conformity?

    Science.gov (United States)

    2010-07-01

    ... conformity? 59.621 Section 59.621 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Families § 59.621 Who may apply for a certificate of conformity? A certificate of conformity may be issued... certificate of conformity. However, in order to hold the certificate, the manufacturer must demonstrate day-to...

  9. 40 CFR 59.603 - How must manufacturers apply good engineering judgment?

    Science.gov (United States)

    2010-07-01

    ... engineering judgment? 59.603 Section 59.603 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... COMMERCIAL PRODUCTS Control of Evaporative Emissions From New and In-Use Portable Fuel Containers Overview and Applicability § 59.603 How must manufacturers apply good engineering judgment? (a) In addition to...

  10. First insight into CD59-like molecules of adult Fasciola hepatica.

    Science.gov (United States)

    Shi, Yunliang; Toet, Hayley; Rathinasamy, Vignesh; Young, Neil D; Gasser, Robin B; Beddoe, Travis; Huang, Weiyi; Spithill, Terry W

    2014-09-01

    The present study focussed on investigating CD59-like molecules of Fasciola hepatica. A cDNA encoding a CD59-like protein (termed FhCD59-1) identified previously in the membrane fraction of the F. hepatica tegument was isolated. This homologue was shown to encode a predicted open reading frame (ORF) of 122 amino acids (aa) orthologous to human CD59 with a 25 aa signal peptide, a mature protein containing 10 cysteines and a conserved CD59/Ly-6 family motif "CCXXXXCN". An analysis of cDNAs from two different adult specimens of F. hepatica revealed seven variable types of FhCD59-1 sequences, designated FhCD59-1.1 to FhCD59-1.7, which had 94.3-99.7% amino acid sequence identity upon pairwise comparison. Molecular modeling of FhCD59-1.1 with human CD59 confirmed the presence of the three-finger protein domain found in the CD59 family and predicted three disulphide bonds in the F. hepatica sequence. The interrogation of F. hepatica databases identified two additional sequences, designated FhCD59-2 and FhCD59-3, which had only 23.4-29.5% amino acid identity to FhCD59-1.1. Orthologues of the inferred CD59 protein sequences of F. hepatica were also identified in other flatworms, including Fasciola gigantica, Fascioloides magna, Schistosoma haematobium, Schistosoma japonicum, Schistosoma mansoni, Clonorchis sinensis, Opisthorchis viverrini, Taenia solium, Echinococcus granulosus and the free living Schmidtea mediterannea. The results revealed a considerable degree of sequence complexity in the CD59-like sequence families in F. hepatica and flatworms. Phylogenetic analysis of CD59-like aa sequences from F. hepatica and flatworms showed that FhCD59-2 clustered with the known surface-associated protein SmCD59-2 of S. mansoni. Relatively well-supported clades specific to schistosomes, fasciolids and opisthorchiids were identified. The qPCR analysis of gene transcription showed that the relative expression of these 3 FhCD59-like sequences varied by 11-47-fold during fluke

  11. Production of human CD59-transgenic pigs by embryonic germ cell nuclear transfer

    Energy Technology Data Exchange (ETDEWEB)

    Ahn, Kwang Sung; Won, Ji Young [Department of Physiology, Dankook University School of Medicine, Cheonan (Korea, Republic of); Park, Jin-Ki [Animal Biotechnology Division, National Institute of Animal Science, Suwon (Korea, Republic of); Sorrell, Alice M. [Department of Physiology, Dankook University School of Medicine, Cheonan (Korea, Republic of); Heo, Soon Young; Kang, Jee Hyun [Department of Nanobiomedical Science, Dankook University, Cheonan (Korea, Republic of); Woo, Jae-Seok [Animal Biotechnology Division, National Institute of Animal Science, Suwon (Korea, Republic of); Choi, Bong-Hwan [Genomics and Bioinformatics Division, National Institute of Animal Science, Suwon (Korea, Republic of); Chang, Won-Kyong [Animal Biotechnology Division, National Institute of Animal Science, Suwon (Korea, Republic of); Shim, Hosup, E-mail: shim@dku.edu [Department of Nanobiomedical Science, Dankook University, Cheonan (Korea, Republic of); Institute of Tissue Regeneration Engineering, Dankook University, Cheonan (Korea, Republic of)

    2010-10-01

    Research highlights: {yields} Human CD59 (hCD59) gene was introduced into porcine embryonic germ (EG) cells. {yields} hCD59-transgenic EG cells were resistant to hyperacute rejection in cytolytic assay. {yields} hCD59-transgenic pigs were produced by EG cell nuclear transfer. -- Abstract: This study was performed to produce transgenic pigs expressing the human complement regulatory protein CD59 (hCD59) using the nuclear transfer (NT) of embryonic germ (EG) cells, which are undifferentiated stem cells derived from primordial germ cells. Because EG cells can be cultured indefinitely in an undifferentiated state, they may provide an inexhaustible source of nuclear donor cells for NT to produce transgenic pigs. A total of 1980 NT embryos derived from hCD59-transgenic EG cells were transferred to ten recipients, resulting in the birth of fifteen piglets from three pregnancies. Among these offspring, ten were alive without overt health problems. Based on PCR analysis, all fifteen piglets were confirmed as hCD59 transgenic. The expression of the hCD59 transgene in the ten living piglets was verified by RT-PCR. Western analysis showed the expression of the hCD59 protein in four of the ten RT-PCR-positive piglets. These results demonstrate that hCD59-transgenic pigs could effectively be produced by EG cell NT and that such transgenic pigs may be used as organ donors in pig-to-human xenotransplantation.

  12. Production of human CD59-transgenic pigs by embryonic germ cell nuclear transfer

    International Nuclear Information System (INIS)

    Ahn, Kwang Sung; Won, Ji Young; Park, Jin-Ki; Sorrell, Alice M.; Heo, Soon Young; Kang, Jee Hyun; Woo, Jae-Seok; Choi, Bong-Hwan; Chang, Won-Kyong; Shim, Hosup

    2010-01-01

    Research highlights: → Human CD59 (hCD59) gene was introduced into porcine embryonic germ (EG) cells. → hCD59-transgenic EG cells were resistant to hyperacute rejection in cytolytic assay. → hCD59-transgenic pigs were produced by EG cell nuclear transfer. -- Abstract: This study was performed to produce transgenic pigs expressing the human complement regulatory protein CD59 (hCD59) using the nuclear transfer (NT) of embryonic germ (EG) cells, which are undifferentiated stem cells derived from primordial germ cells. Because EG cells can be cultured indefinitely in an undifferentiated state, they may provide an inexhaustible source of nuclear donor cells for NT to produce transgenic pigs. A total of 1980 NT embryos derived from hCD59-transgenic EG cells were transferred to ten recipients, resulting in the birth of fifteen piglets from three pregnancies. Among these offspring, ten were alive without overt health problems. Based on PCR analysis, all fifteen piglets were confirmed as hCD59 transgenic. The expression of the hCD59 transgene in the ten living piglets was verified by RT-PCR. Western analysis showed the expression of the hCD59 protein in four of the ten RT-PCR-positive piglets. These results demonstrate that hCD59-transgenic pigs could effectively be produced by EG cell NT and that such transgenic pigs may be used as organ donors in pig-to-human xenotransplantation.

  13. Sequestration of host-CD59 as potential immune evasion strategy of Trichomonas vaginalis.

    Science.gov (United States)

    Ibáñez-Escribano, Alexandra; Nogal-Ruiz, Juan José; Pérez-Serrano, Jorge; Gómez-Barrio, Alicia; Escario, J Antonio; Alderete, J F

    2015-09-01

    Trichomonas vaginalis is known to evade complement-mediated lysis. Because the genome of T. vaginalis does not possess DNA sequence with homology to human protectin (CD59), a complement lysis restricting factor, we tested the hypothesis that host CD59 acquisition by T. vaginalis organisms mediates resistance to complement killing. This hypothesis was based on the fact that trichomonads are known to associate with host proteins. No CD59 was detected on the surface of T. vaginalis grown in serum-based medium using as probe anti-CD59 monoclonal antibody (MAb). We, therefore, infected mice intraperitoneally with live T. vaginalis, and trichomonads harvested from ascites were tested for binding of CD59. Immunofluorescence showed that parasites had surface CD59. Furthermore, as mouse erythrocytes (RBCs) possess membrane-associated CD59, and trichomonads use RBCs as a nutrient source, organisms were co-cultured with murine RBCs for one week. Parasites were shown to have detectable surface CD59. Importantly, live T. vaginalis with bound CD59 were compared with batch-grown parasites without surface-associated CD59 for sensitivity to complement in human serum. Trichomonads without surface-bound CD59 had a higher level of killing by complement than did parasites with surface CD59. These data show that host CD59 acquired onto the surface by live T. vaginalis may be an alternative mechanism for complement evasion. We describe a novel strategy by T. vaginalis consistent with host protein procurement by this parasite to evade the lytic action of complement. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Ultrasound Assisted Synthesis of 5,9-Dimethylpentadecane and 5,9-Dimethylhexadecane – the Sex Pheromones of Leucoptera coffeella

    Directory of Open Access Journals (Sweden)

    Fritz Duus

    2007-08-01

    Full Text Available Racemic 5,9-dimethylpentadecane and 5,9-dimethylhexadecane, the major and minor constituents, respectively, of the sex pheromone of Leucoptera coffeella, have been synthesized from citronellol in 56-58% overall yield through six steps. Ultrasound irradiation efficiently supported tosylation of alcohols (two steps as well as the subsequent cross coupling reactions with the pertinent Grignard reagents (also two steps.

  15. Thermal effects from modified endodontic laser tips used in the apical third of root canals with erbium-doped yttrium aluminium garnet and erbium, chromium-doped yttrium scandium gallium garnet lasers.

    Science.gov (United States)

    George, Roy; Walsh, Laurence J

    2010-04-01

    To evaluate the temperature changes occurring on the apical third of root surfaces when erbium-doped yttrium aluminium garnet (Er:YAG) and erbium, chromium-doped yttrium scandium gallium garnet (Er,Cr:YSGG) laser energy was delivered with a tube etched, laterally emitting conical tip and a conventional bare design optical fiber tip. Thermal effects of root canal laser treatments on periodontal ligament cells and alveolar bone are of concern in terms of safety. A total of 64 single-rooted extracted teeth were prepared 1 mm short of the working length using rotary nickel-titanium Pro-Taper files to an apical size corresponding to a F5 Pro-Taper instrument. A thermocouple located 2 mm from the apex was used to record temperature changes arising from delivery of laser energy through laterally emitting conical tips or plain tips, using an Er:YAG or Er,Cr:YSGG laser. For the Er:YAG and Er,Cr:YSGG systems, conical fibers showed greater lateral emissions (452 + 69% and 443 + 64%) and corresponding lower forward emissions (48 + 5% and 49 + 5%) than conventional plain-fiber tips. All four combinations of laser system and fiber design elicited temperature increases less than 2.5 degrees C during lasing. The use of water irrigation attenuated completely the thermal effects of individual lasing cycles. Laterally emitting conical fiber tips can be used safely under defined conditions for intracanal irradiation without harmful thermal effects on the periodontal apparatus.

  16. Preparation and biodistribution of {sup 59}Fe-radiolabelled iron oxide nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Pospisilova, Martina, E-mail: martinapospisilova@gmail.com; Zapotocky, Vojtech; Nesporova, Kristina [Contipro a.s (Czech Republic); Laznicek, Milan; Laznickova, Alice [Charles University, Faculty of Pharmacy in Hradec Králové (Czech Republic); Zidek, Ondrej; Cepa, Martin; Vagnerova, Hana; Velebny, Vladimir [Contipro a.s (Czech Republic)

    2017-02-15

    We report on the {sup 59}Fe radiolabelling of iron oxide nanoparticle cores through post-synthetic isotope exchange ({sup 59}Fe-IONP{sub ex}) and precursor labelling ({sup 59}Fe-IONP{sub pre}). Scanning electron microscopy and dynamic light scattering measurements showed no impact of radiolabelling on nanoparticle size or morphology. While incorporation efficiencies of these methods are comparable—83 and 90% for precursor labelling and post-synthetic isotope exchange, respectively—{sup 59}Fe-IONP{sub pre} exhibited much higher radiochemical stability in citrated human plasma. Quantitative ex vivo biodistribution study of {sup 59}Fe-IONP{sub pre} coated with triethylene glycol was performed in Wistar rats. Following the intravenous administration, high {sup 59}Fe concentration was observed in the lung and the organs of the reticuloendothelial system such as the liver, the spleen and the femur.

  17. 59th Medical Wing Clinical Research Division Clinical Investigations Program Pathology Poster

    Science.gov (United States)

    2017-04-28

    59 MDW/SGVU SUBJECT: Professional Presentation Approval 1. Your paper, entitled 59th Medical Wing Clinical Research Division Clinical Investigations...Program Pathology Poster presented at/published to For hanging in a hallway of the 591h Medical Wing Clinical Research Division, Bldg 4430 in...Graduate Health Sciences Education student and your department has told you they cannot fund your publication, the 59th Clinical Research Division may

  18. Intrinsically radiolabelled [59Fe]-SPIONs for dual MRI/radionuclide detection

    OpenAIRE

    Hoffman, David; Sun, Minghao; Yang, Likun; McDonagh, Philip R; Corwin, Frank; Sundaresan, Gobalakrishnan; Wang, Li; Vijayaragavan, Vimalan; Thadigiri, Celina; Lamichhane, Narottam; Zweit, Jamal

    2014-01-01

    Towards the development of iron oxide nanoparticles with intrinsically incorporated radionuclides for dual Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) and more recently of Single Photon Emission Computed Tomography/Magnetic Resonance Imaging (SPECT/MRI), we have developed intrinsically radiolabeled [59Fe]-superparamagnetic iron oxide nanoparticles ([59Fe]-SPIONs) as a proof of concept for an intrinsic dual probe strategy. 59Fe was incorporated into Fe3O4 nanoparticle cry...

  19. The migration, accumulation and distribution of 59Fe in rice plants and soils

    International Nuclear Information System (INIS)

    Wang Yumin; Xu Shiming; Xu Guanren

    1990-07-01

    The 59 Fe is one of radionuclides in the waste water discharged from nuclear power plants. The accumulation and distribution of 59 Fe in rice plants at different growing stages and the accumulation and migration in soils of different textures were studied by using solution containing 59 FeCl 3 as a tracer. At the same contaminated activity, the distribution in the soils are discussed. According to the biological consequences caused by 59 Fe entering indirectly into agroecological environment, the possible methods for treatment and utilization of agricultural products are suggested

  20. Evaluation of 59Co(n,γ)60Co, 59Co(n,2n)58Co, 59Co(nα)56Mn, for ENDF/B-IV

    International Nuclear Information System (INIS)

    Krieger, T.J.; Smith, A.B.; Smith, D.L.; Jenkins, J.D.

    1975-01-01

    The present evaluation of 59 Co (n,γ) for ENDF/B IV consists of two parts, an evaluation below 100 keV by T. J. Krieger, Brookhaven National Laboratory, and one above 100 keV by A. B. Smith and D. L. Smith, Argonne National Laboratory

  1. 36 CFR 5.9 - Discrimination in furnishing public accommodations and transportation services.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Discrimination in furnishing public accommodations and transportation services. 5.9 Section 5.9 Parks, Forests, and Public Property... furnishing public accommodations and transportation services. (a) The proprietor, owner or operator and the...

  2. 46 CFR 59.10-20 - Patches in shells and tube sheets.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Patches in shells and tube sheets. 59.10-20 Section 59.10-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING REPAIRS TO... wasted portion with a new section. The ligaments between the tube holes may be joined by means of welding...

  3. 28 CFR 59.5 - Functions and authorities of the Deputy Assistant Attorneys General.

    Science.gov (United States)

    2010-07-01

    ... Assistant Attorneys General. 59.5 Section 59.5 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED... authorities of the Deputy Assistant Attorneys General. The functions and authorities of the Deputy Assistant Attorneys General set out in this part may at any time be exercised by an Assistant Attorney General, the...

  4. C59N+ and C69N+: isoelectronic heteroanalogues of C60 and C70

    International Nuclear Information System (INIS)

    Lamparth, I.; Nuber, B.; Schick, G.; Skiebe, A.; Groesser, T.; Hirsch, A.

    1995-01-01

    Fragmentation reactions in the mass spectrometer were used to generate the first characterized nitrogen heterofullerene ions C 59 N + and C 69 N + from regioselectively synthesized oligoiminofullerenes. During this process one carbon atom in the fullerene core is removed and replaced with a nitrogen atom. C 59 N + has almost the same structure as the isoelectronic C 60 . (orig.)

  5. Gecko CD59 Is Implicated in Proximodistal Identity during Tail Regeneration

    Science.gov (United States)

    Jiang, Shengjuan; Zhou, Weijuan; Liu, Yan; Wang, Yingjie; Gu, Qing; Gu, Yun; Dong, Yingying; Liu, Mei; Gu, Xingxing; Ding, Fei; Gu, Xiaosong

    2011-01-01

    Several adult reptiles, such as Gekko japonicus, have the ability to precisely re-create a missing tail after amputation. To ascertain the associated acquisition of positional information from blastemal cells and the underlying molecular mechanism of tail regeneration, a candidate molecule CD59 was isolated from gecko. CD59 transcripts displayed a graded expression in the adult gecko spinal cord with the highest level in the anterior segment, with a stable expression along the normal tail. After tail amputation, CD59 transcripts in the spinal cord proximal to the injury sites increased markedly at 1 day and 2 weeks; whereas in the regenerating blastema, strong CD59 positive signals were detected in the blastemal cells anterior to the blastema, with a gradual decrease along the proximodistal (PD) axis. When treated with RA following amputation, CD59 transcripts in the blastema were up-regulated. PD confrontation assays revealed that the proximal blastema engulfed the distal one after in vitro culture, and rabbit-anti human CD59 antibody was able to block this PD engulfment. Overexpression of the CD59 during tail regeneration causes distal blastemal cells to translocate to a more proximal location. Our results suggest that position identity is not restricted to amphibian limb regeneration, but has already been established in tail blastema of reptiles. The CD59, a cell surface molecule, acted as a determinant of proximal–distal cell identity. PMID:21464923

  6. 40 CFR 59.510 - What records am I required to maintain?

    Science.gov (United States)

    2010-07-01

    ... PROGRAMS (CONTINUED) NATIONAL VOLATILE ORGANIC COMPOUND EMISSION STANDARDS FOR CONSUMER AND COMMERCIAL PRODUCTS National Volatile Organic Compound Emission Standards for Aerosol Coatings § 59.510 What records... providing the written certification to the Administrator in accordance with § 59.511(g), the certifying...

  7. 40 CFR 59.685 - What symbols, acronyms, and abbreviations does this subpart use?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false What symbols, acronyms, and abbreviations does this subpart use? 59.685 Section 59.685 Protection of Environment ENVIRONMENTAL PROTECTION... CONSUMER AND COMMERCIAL PRODUCTS Control of Evaporative Emissions From New and In-Use Portable Fuel...

  8. 49 CFR 174.59 - Marking and placarding of rail cars.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Marking and placarding of rail cars. 174.59... RAIL General Handling and Loading Requirements § 174.59 Marking and placarding of rail cars. No person may transport a rail car carrying hazardous materials unless it is marked and placarded as required by...

  9. 22 CFR 41.59 - Professionals under the North American Free Trade Agreement.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Professionals under the North American Free Trade Agreement. 41.59 Section 41.59 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF... Professionals under the North American Free Trade Agreement. (a) Requirements for classification as a NAFTA...

  10. 10 CFR 71.59 - Standards for arrays of fissile material packages.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Standards for arrays of fissile material packages. 71.59 Section 71.59 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PACKAGING AND TRANSPORTATION OF RADIOACTIVE.... The value of the CSI may be zero provided that an unlimited number of packages are subcritical, such...

  11. 42 CFR 59.1 - To what programs do these regulations apply?

    Science.gov (United States)

    2010-10-01

    ... FOR FAMILY PLANNING SERVICES Project Grants for Family Planning Services § 59.1 To what programs do... 42 Public Health 1 2010-10-01 2010-10-01 false To what programs do these regulations apply? 59.1... of voluntary family planning projects. These projects shall consist of the educational, comprehensive...

  12. 40 CFR 59.629 - What decisions may EPA make regarding my certificate of conformity?

    Science.gov (United States)

    2010-07-01

    ... my certificate of conformity? 59.629 Section 59.629 Protection of Environment ENVIRONMENTAL... certificate of conformity? (a) If we determine your application is complete and shows that the emission family meets all the requirements of this subpart and the Act, we will issue a certificate of conformity for...

  13. 44 CFR 5.59 - Judicial relief available to the public.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Judicial relief available to the public. 5.59 Section 5.59 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... the complainant resides, or has his principal place of business, or in which the agency records are...

  14. 7 CFR 59.102 - Mandatory daily reporting for cows and bulls.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Mandatory daily reporting for cows and bulls. 59.102... (CONTINUED) LIVESTOCK MANDATORY REPORTING Cattle Reporting § 59.102 Mandatory daily reporting for cows and bulls. (a) In General. The corporate officers or officially designated representatives of each cow and...

  15. Structural Analysis Of CD59 Of Chinese Tree Shrew: A New Reference Molecule For Human Immune System Specific CD59 Drug Discovery.

    Science.gov (United States)

    Panda, Subhamay; Kumari, Leena; Panda, Santamay

    2017-11-17

    Chinese tree shrews (Tupaia belangeri chinensis) bear several characteristics that are considered to be very crucial for utilizing in animal experimental models in biomedical research. Subsequent to the identification of key aspects and signaling pathways in nervous and immune systems, it is revealed that tree shrews acquires shared common as well as unique characteristics, and hence offers a genetic basis for employing this animal as a prospective model for biomedical research. CD59 glycoprotein, commonly referred to as MAC-inhibitory protein (MAC-IP), membrane inhibitor of reactive lysis (MIRL), or protectin, is encoded by the CD59 gene in human beings. It is the member of the LY6/uPAR/alpha-neurotoxin protein family. With this initial point the objective of this study was to determine a comparative composite based structure of CD59 of Chinese tree shrew. The additional objective of this study was to examine the distribution of negatively and positively charged amino acid over molecular modeled structure, distribution of secondary structural elements, hydrophobicity molecular surface analysis and electrostatic potential analysis with the assistance of several bioinformatical analytical tools. CD59 Amino acid sequence of Chinese tree shrew collected from the online database system of National Centre for Biotechnology Information. SignalP 4.0 online server was employed for detection of signal peptide instance within the protein sequence of CD59. Molecular model structure of CD59 protein was generated by the Iterative Threading ASSEmbly Refinement (I-TASSER) suite. The confirmation for three-dimensional structural model was evaluated by structure validation tools. Location of negatively and positively charged amino acid over molecular modeled structure, distribution of secondary structural elements, and hydrophobicity molecular surface analysis was performed with the help of Chimera tool. Electrostatic potential analysis was carried out with the adaptive Poisson

  16. Some characteristics of the retention distribution and internal doses of 59Fe in rats

    International Nuclear Information System (INIS)

    Wang Deheng; Tian Wuxun; Zhang Hongyuan; Wen Quanfa; Hu Yuexin; Zhao Shanyin

    1993-01-01

    After gastric incubation, the whole body 59 Fe-retentions in rats were fit to two compartment exponential equations. The biological half life for 59 Fe in the slow compartment are 95 and 109 days for young and adult rats respectively, not statistically significantly different. The main 59 Fe-accumulative organs are liver and bone marrow. The biological eliminations of 59 Fe from most organs in young rats are faster than in adult rats. The young rats get more total accumulative dose in organs except liver and total body and have a faster dose accumulative speed than the adult rats. Equal quantities of 59 Fe P.O. may probably give young rats more intensive biological effects than adult rats

  17. 59Fe uptake by Salmonella typhimurium strains of different epidemiological sources

    International Nuclear Information System (INIS)

    Rabsch, W.; Reissbrodt, R.

    1985-01-01

    All Salmonella typhimurium strains tested were able to use iron from transferrin. In buffered nutrient broth - poor in iron-content - the strains were tested in 59 FeCl 3 and 59 Fe-transferrin uptake in different growth phases. In the early log phase the strains are able to catch the 59 Fe 3+ in a very great amount as it is necessary for the growth. The content of 59 Fe per cell was in the late log phase reduced until to a value, which seen to be enough for growth. The acquisition of 59 Fe-transferrin between the early and late log phase tested by 4 S. typhimurium strains was different. (author)

  18. Fragmentation of neutron-hole strengths in 59Ni observed in the 60Ni(p, d) 59Ni reaction at 65 MeV

    International Nuclear Information System (INIS)

    Matoba, M.; Ohgaki, H.; Kugimiya, H.; Ijiri, H.; Maki, T.; Nakano, M.

    1995-01-01

    The 60 Ni(p, d) 59 Ni reaction has been studied with 65 MeV polarized protons. Angular distributions of the differential cross section and analyzing power have been measured for neutron hole states in 59 Ni up to the excitation energies of 7 MeV. The data analysis with a standard distorted-wave Born approximation theory provides transferred angular momenta l, j and spectroscopic factors for thirty-nine transitions. The nuclear damping mechanism of the single hole states is discussed. ((orig.))

  19. CD59 Underlines the Antiatherosclerotic Effects of C-Phycocyanin on Mice

    Directory of Open Access Journals (Sweden)

    Bing Li

    2013-01-01

    Full Text Available The effects of C-phycocyanin (C-PC on atherosclerosis and the regulatory effects of CD59 gene on anti-atherosclerotic roles of C-PC were investigated. Apolipoprotein E knockout (ApoE(−/− mice were randomly divided into four groups: control group, C-PC treatment group, CD59 transfection group and C-PC+CD59 synergy group. The mice were fed with high-fat-diet and treated with drug intervention at the same time. Results showed the atherosclerotic mouse model was successfully established. CD59 was over-expressed in blood and tissue cells. Single CD59 or C-PC could reduce blood lipid levels and promote the expression of anti-apoptotic Bcl-2 but inhibit pro-apoptotic Fas proteins in endothelial cells. The expression levels of cell cycle protein D1 (Cyclin D1 and mRNA levels of cyclin dependent protein kinase 4 (CDK4 in smooth muscle cells were restrained by CD59 and C-PC. CD59 or C-PC alone could inhibit the formation of atherosclerotic plaque by suppressing MMP-2 protein expression. In addition, C-PC could promote CD59 expression. So both CD59 and C-PC could inhibit the progress of atherosclerosis, and the anti-atherosclerotic effects of C-PC might be fulfilled by promoting CD59 expression, preventing smooth muscle cell proliferation and the apoptosis of endothelial cells, reducing blood fat levels, and at last inhibiting the development of atherosclerosis.

  20. Intrinsically radiolabelled [(59)Fe]-SPIONs for dual MRI/radionuclide detection.

    Science.gov (United States)

    Hoffman, David; Sun, Minghao; Yang, Likun; McDonagh, Philip R; Corwin, Frank; Sundaresan, Gobalakrishnan; Wang, Li; Vijayaragavan, Vimalan; Thadigiri, Celina; Lamichhane, Narottam; Zweit, Jamal

    2014-01-01

    Towards the development of iron oxide nanoparticles with intrinsically incorporated radionuclides for dual Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) and more recently of Single Photon Emission Computed Tomography/Magnetic Resonance Imaging (SPECT/MRI), we have developed intrinsically radiolabeled [(59)Fe]-superparamagnetic iron oxide nanoparticles ([(59)Fe]-SPIONs) as a proof of concept for an intrinsic dual probe strategy. (59)Fe was incorporated into Fe3O4 nanoparticle crystal lattice with 92±3% efficiency in thermal decomposition synthesis. Multidentate poly(acrylic acid)-dopamine-poly(ethylene-glycol-2000) (PAA-DOP-PEG) ligands were designed and synthesized based on facile EDC chemistry and utilized to functionalize the [(59)Fe]-SPIONs. The transverse relaxivity of [(59)Fe]-SPIONs (97±3 s(-1)mM(-1)) was characterized and found to be similar to non-radioactive SPIONs (72±10 s(-1)mM(-1)), indicating that (59)Fe incorporation does not alter the SPIONs' MRI contrast properties. [(59)Fe]-SPIONs were used to evaluate the nanoparticle biodistribution by ex vivo gamma counting and MRI. Nude mice (n=15) were injected with [(59)Fe]-SPIONs and imaged at various time points with 7T small animal MRI scanner. Ex vivo biodistribution was evaluated by tissue-based gamma counting. MRI signal contrast qualitatively correlates with the %ID/g of [(59)Fe]-SPIONs, with high contrast in liver (45±6%), medium contrast in kidneys (21±5%), and low contrast in brain (4±6%) at 24 hours. This work demonstrates the synthesis and in vivo application of intrinsically radiolabeled [(59)Fe]-SPIONs for bimodal detection and provides a proof of concept for incorporation of both gamma- and positron-emitting inorganic radionuclides into the core of metal based MRI contrast agent nanoparticles.

  1. Slide 59

    Indian Academy of Sciences (India)

    Erythropoeitin, Cytokines, blood factors, HuMABs etc) market is worth more than 100 billion dollars. Indian Pharma industry has concentrated only on Biogenerics so far. Apart from cost-effectiveness, Smarter and better protein drugs are desirable! Indeed ...

  2. The Electronic Structure of C59N and Its AxC59N (A=K, Rb, Cs) Salts from High Energy Spectroscopy

    NARCIS (Netherlands)

    Golden, M.S.; Pichler, T.; Knupfer, M.; Friedlein, R.; Haffner, S.; Fink, J.; Andreoni, W.; Curioni, A.; Keshavarz-K, M.; Bellavia-Lund, C.; Sastre, A.; Hummelen, J.-C.; Wudl, F.

    1998-01-01

    Using a combination of results from photoemission, electron energy-loss spectroscopy in transmission and gradient-corrected density functional calculations, we have examined the effects of chemical substitution of N for C in the dimerised heterofullerene (C59N)2. We show that there is a new HOMO

  3. 47 CFR 59.4 - Definition of “qualifying carrier”.

    Science.gov (United States)

    2010-10-01

    ... (CONTINUED) INFRASTRUCTURE SHARING § 59.4 Definition of “qualifying carrier”. For purposes of this part, the term “qualifying carrier” means a telecommunications carrier that: (a) Lacks economies of scale or...

  4. Improved detection limit for {sup 59}Ni using the technique of accelerator mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Persson, Per; Erlandsson, Bengt; Hellborg, Ragnar; Kiisk, Madis; Larsson, Ragnar; Skog, Goeran; Stenstroem, Kristina [Lund Univ. (Sweden). Dept. of Nuclear Physics

    2002-11-01

    59 Ni is produced by neutron activation in the stainless steel close to the core of a nuclear reactor. To be able to classify the different parts of the reactor with respect to their content of long-lived radionuclides before final storage it is important to measure the 59 Ni level. Accelerator mass spectrometry is an ultra-sensitive method for counting atoms, suitable for 59 Ni measurements. Improvements in the reduction of the background and in the chemical reduction of cobalt, the interfering isobar, have been made. This chemical purification is essential when using small tandem accelerators, <3 MV, combined with the detection of characteristic projectile X-rays. These improvements have lowered the detection limit for 59 Ni by a factor of twenty compared with the first value reported for the Lund AMS facility. Material from the Swedish nuclear industry has been analysed and examples of the results are presented.

  5. Absorption and translocation of 59Fe and 14C-rhodotorulate in iron-stressed tomato

    International Nuclear Information System (INIS)

    Miller, G.W.; Shigematsu, A.; Motoji, N.; Shibabe, S.

    1990-01-01

    Tomato plants, cultivars FER and Earlygirl (both iron efficient and able to use rhodotorulate- 59 Fe), were grown under low Fe conditions for 9 days. Rhodotorulate- 14 C, isolated from Rhodotorula pilimanae cultured with 14 C-sucrose, and rhodotorulate- 59 Fe were added to the Fe-stressed plants for 6-, 24- or 48-h periods. It was evident from autoradiograms and tissue sampling that 59 Fe and 14 C were abundant in roots, stems and leaves. The 14 C autoradiograms showed especially high density in the small, younger leaves, as was found also with 59 Fe. Unlike synthetic chelates, rhodotorulate (or metabolised derivatives) was readily absorbed by the roots and translocated to the leaves. (author)

  6. The history of MF59(®) adjuvant: a phoenix that arose from the ashes.

    Science.gov (United States)

    O'Hagan, Derek T; Ott, Gary S; Nest, Gary Van; Rappuoli, Rino; Giudice, Giuseppe Del

    2013-01-01

    The first clinical trial of an MF59(®)-adjuvanted influenza vaccine (Novartis) was conducted 20 years ago in 1992. The product that emerged (Fluad(®), Novartis) was licensed first in Italy in 1997 and is now licensed worldwide in 30 countries. US licensure is expected in the coming years. By contrast, many alternative adjuvanted vaccines have failed to progress. The key decisions that allowed MF59 to succeed in such a challenging environment are highlighted here and the lessons that were learned along the way are discussed. MF59 was connected to vaccines that did not succeed and was perceived as a 'failure' before it was a success. Importantly, it never failed for safety reasons and was always well tolerated. Even when safety issues have emerged for alternative adjuvants, careful analysis of the substantial safety database for MF59 have shown that there are no significant concerns with widespread use, even in more 'sensitive' populations.

  7. Road safety audit for the intersection of US 59 and IA 9 in Osceola County, Iowa.

    Science.gov (United States)

    2012-03-01

    The Iowa Department of Transportation (DOT) requested a road safety audit (RSA) of the US 59/IA 9 intersection in northwestern Iowa, just south of the Minnesota border, to assess intersection environmental issues and crash history and recommend appro...

  8. Human papillomavirus type 59 immortalized keratinocytes express late viral proteins and infectious virus after calcium stimulation

    International Nuclear Information System (INIS)

    Lehr, Elizabeth E.; Qadadri, Brahim; Brown, Calla R.; Brown, Darron R.

    2003-01-01

    Human papillomavirus type 59 (HPV 59) is an oncogenic type related to HPV 18. HPV 59 was recently propagated in the athymic mouse xenograft system. A continuous keratinocyte cell line infected with HPV 59 was created from a foreskin xenograft grown in an athymic mouse. Cells were cultured beyond passage 50. The cells were highly pleomorphic, containing numerous abnormally shaped nuclei and mitotic figures. HPV 59 sequences were detected in the cells by DNA in situ hybridization in a diffuse nuclear distribution. Southern blots were consistent with an episomal state of HPV 59 DNA at approximately 50 copies per cell. Analysis of the cells using a PCR/reverse blot strip assay, which amplifies a portion of the L1 open reading frame, was strongly positive. Differentiation of cells in monolayers was induced by growth in F medium containing 2 mM calcium chloride for 10 days. Cells were harvested as a single tissue-like sheet, and histologic analysis revealed a four-to-six cell-thick layer. Transcripts encoding involucrin, a cornified envelope protein, and the E1-circumflexE4 and E1-circumflexE4-circumflexL1 viral transcripts were detected after several days of growth in F medium containing 2 mM calcium chloride. The E1-circumflexE4 and L1 proteins were detected by immunohistochemical analysis, and virus particles were seen in electron micrographs in a subset of differentiated cells. An extract of differentiated cells was prepared by vigorous sonication and was used to infect foreskin fragments. These fragments were implanted into athymic mice. HPV 59 was detected in the foreskin xenografts removed 4 months later by DNA in situ hybridization and PCR/reverse blot assay. Thus, the complete viral growth cycle, including production on infectious virus, was demonstrated in the HPV 59 immortalized cells grown in a simple culture system

  9. Infection with the oncogenic human papillomavirus type 59 alters protein components of the cornified cell envelope

    International Nuclear Information System (INIS)

    Lehr, Elizabeth; Brown, Darron R.

    2003-01-01

    Infection of the genital tract with human papillomaviruses (HPVs) leads to proliferative and dysplastic epithelial lesions. The mechanisms used by the virus to escape the infected keratinocyte are not well understood. Infection of keratinocytes with HPV does not cause lysis, the mechanism used by many viruses to release newly formed virions. For HPV 11, a type associated with a low risk of neoplastic disease, the cornified cell envelope (CCE) of infected keratinocytes is thin and fragile, and transcription of loricrin, the major CCE protein, is reduced. The effects of high-risk HPV infection on components of the CCE have not been previously reported. HPV 59, an oncogenic genital type related to HPV types 18 and 45 was identified in a condylomata acuminata lesion. An extract of this lesion was used to infect human foreskin fragments, which were grown in athymic mice as xenografts. Continued propagation using extracts of xenografts permitted growth of additional HPV 59-infected xenografts. CCEs purified from HPV 59-infected xenografts displayed subtle morphologic abnormalities compared to those derived from uninfected xenografts. HPV 59-infected xenografts revealed dysplastic-appearing cells with mitotic figures. Detection of loricrin, involucrin, and cytokeratin 10 was reduced in HPV 59-infected epithelium, while small proline-rich protein 3 (SPR3) was increased. Reduction in loricrin was most apparent in regions of epithelium containing abundant HPV 59 DNA. Compared to uninfected epithelium, loricrin transcription was decreased in HPV 59-infected epithelium. We conclude that HPV 59 shares with HPV 11 the ability to alter CCE components and to specifically reduce transcription of the loricrin gene. Because loricrin is the major CCE protein, a reduction in this component could alter the physical properties of the CCE, thus facilitating virion release

  10. Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in mice

    Directory of Open Access Journals (Sweden)

    Nietfeld Wilfried

    2010-03-01

    Full Text Available Abstract Background The complement system is a crucial mediator of inflammation and cell lysis after cerebral ischemia. However, there is little information about the exact contribution of the membrane attack complex (MAC and its inhibitor-protein CD59. Methods Transient focal cerebral ischemia was induced by middle cerebral artery occlusion (MCAO in young male and female CD59a knockout and wild-type mice. Two models of MCAO were applied: 60 min MCAO and 48 h reperfusion, as well as 30 min MCAO and 72 h reperfusion. CD59a knockout animals were compared to wild-type animals in terms of infarct size, edema, neurological deficit, and cell death. Results and Discussion CD59a-deficiency in male mice caused significantly increased infarct volumes and brain swelling when compared to wild-type mice at 72 h after 30 min-occlusion time, whereas no significant difference was observed after 1 h-MCAO. Moreover, CD59a-deficient mice had impaired neurological function when compared to wild-type mice after 30 min MCAO. Conclusion We conclude that CD59a protects against ischemic brain damage, but depending on the gender and the stroke model used.

  11. Study of Deafness Associated with DFNB59 Gene (pejvakin Mutation in Fars Province

    Directory of Open Access Journals (Sweden)

    S Raeisi

    2012-05-01

    Full Text Available

    Background and Objectives: Hearing loss is the most frequent sensory disorder affecting 1 in 500 neonates with more than 50% of inherited cases. This trait is a very heterogeneous disorder and happens due to genetic or environmental causes or both. More than 46 genes may be involved in non-syndromic hearing loss. Recently, DFNB59 gene has been shown to cause deafness in some Iranian populations. The aim of this study was to determine the role of DFNB59 gene mutations causing deafness in a group of 130 deaf pupils in Fars province. Methods: This descriptive-laboratory based study investigated the frequency of DFNB59 gene mutations using PCR-SSCP/HA strategy. Results: Two different DFNB59 polymorphism including 874G>A and 793C>G were found in 1 and 9 of 130 patients studied respectively. However, no DFNB59 mutation was identified. Conclusion: The results of this study shows that the association of DFNB59 mutations with deafness in Fars province is very low.

  12. International need of discussion concerning the implementation of the guideline 2013/59/Euratom; Internationaler Diskussionsbedarf bei der Umsetzung der Richtlinie 2013/59/Euratom

    Energy Technology Data Exchange (ETDEWEB)

    Brendebach, Boris [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) gGmbH, Koeln (Germany). Fachgebiet ' ' Stilllegung' '

    2017-10-01

    The implementation of the requirements of the guideline 2014/59/Euratom (radiation protection safety standards) is challenging for a number of EU member states. Several initiatives were introduced to support the member states accomplishing these challenges. In the frame of the initiatives indications were identified with respect to the need of harmonization for the embodiment of the regulations and the need of the recommendations for the implementation of the requirements. The contribution describes several initiatives and demonstrates exemplary the extracted insights.

  13. Characterization of Pm59, a novel powdery mildew resistance gene in Afghanistan wheat landrace PI 181356.

    Science.gov (United States)

    Tan, Chengcheng; Li, Genqiao; Cowger, Christina; Carver, Brett F; Xu, Xiangyang

    2018-05-01

    A new powdery mildew resistance gene, designated Pm59, was identified in Afghanistan wheat landrace PI 181356, and mapped in the terminal region of the long arm of chromosome 7A. Powdery mildew, caused by Blumeria graminis f. sp. tritici (Bgt), is an important foliar disease of wheat worldwide. In the Great Plains of the USA, Bgt isolates virulent to widely used powdery mildew resistance genes, such as Pm3a, were previously identified. The objectives of this study were to characterize the powdery mildew resistance gene in Afghanistan landrace PI 181356, which exhibited high resistance to Bgt isolates collected in southern Great Plains, and identify molecular markers for marker-assisted selection. An F 2 population and F 2:3 lines derived from a cross between PI 181356 and OK1059060-126135-3 were used in this study. Genetic analysis indicated that PI 181356 carries a single dominant gene, designated Pm59, in the terminal region of the long arm of chromosome 7A. Pm59 was mapped to an interval between sequence tag site (STS) markers Xmag1759 and Xmag1714 with genetic distances of 0.4 cM distal to Xmag1759 and 5.7 cM proximal to Xmag1714. Physical mapping suggested that Pm59 is in the distal bin 7AL 0.99-1.00. Pm59 is a novel powdery mildew resistance gene, and confers resistance to Bgt isolates collected from the Great Plains and the state of Montana. Therefore, Pm59 can be used to breed powdery mildew-resistant cultivars in these regions. Xmag1759 is ideal for marker-assisted selection of Pm59 in wheat breeding.

  14. Characterization of electrochemical and passive behaviour of Alloy 59 in acid solution

    International Nuclear Information System (INIS)

    Luo, Hong; Gao, Shujun; Dong, Chaofang; Li, Xiaogang

    2014-01-01

    Highlights: • A considerably thinner n-type passive film is observed on the Alloy-59. • The passive film formed in air was thicker than that formed in acid solution. • Primary constituents of passive film in air and acid solution are (Cr, Ni)-oxides and (Cr, Ni) hydroxides, respectively. - Abstract: The electrochemical behaviour and passive film properties of the Alloy 59 in sulfuric acid solution was evaluated by the potentiodynamic electrochemical measurements, electrochemical impedance spectroscopy, Mott-Schottky approach, and ex situ surface analytical technique as X-ray photoelectron spectroscopy (XPS) and Auger Electronic Spectrometer (AES). The results confirmed that the Alloy 59 exhibits well passive behaviour. A considerably thinner n-type passive film is observed on this type alloy. Based on the evaluations of surface composition analysis, the primary constituents of passive film formed in the air and acid solution are different, with the (Cr, Ni)-oxides and (Cr, Ni) hydroxides, respectively

  15. Magnetic dipole moments of 58Cu and 59Cu by in-source laser spectroscopy

    International Nuclear Information System (INIS)

    Stone, N. J.; Koester, U.; Stone, J. Rikovska; Fedorov, D. V.; Fedoseyev, V. N.; Flanagan, K. T.; Hass, M.; Lakshmi, S.

    2008-01-01

    Online measurements of the magnetic dipole moments and isotope shifts of 58 Cu and 59 Cu by the in-source laser spectroscopy method are reported. The results for the magnetic moments are μ ( 58 Cu) =+0.52(8) μ N ,μ( 59 Cu) =+1.84(3) μ N and for the isotope shifts δν 59,65 =1.72(22) GHz and δν 58,65 =1.99(30) GHz in the transition from the 3d 10 4s 2 S 1/2 ground state to the 3d 10 4p 2 P 1/2 state in Cu I. The magnetic moment of 58 Cu is discussed in the context of the strength of the subshell closure at 56 Ni, additivity rules and large-scale shell model calculations

  16. Safety and effectiveness of MF-59 adjuvanted influenza vaccines in children and adults.

    Science.gov (United States)

    Black, Steven

    2015-06-08

    The squalene oil-in-water emulsion MF-59 adjuvant was developed initially to enhance the immunogenicity of influenza vaccines in populations such as children and adults with known suboptimal response. Developed in the 1990s, it was initially licensed in Europe for use in seasonal influenza vaccine in the elderly. Since that time, both Avian and p2009H1N1 vaccines have also been developed. Overall, more than 30,000 individuals have participated in clinical trials of MF-59 adjuvanted vaccine and more than 160 million doses of licensed vaccine have been administered. Safety and effectiveness data from clinical trials and observation studies attest to the safety of MF-59 and to its ability to enhance the effectiveness of influenza vaccines in children and the elderly. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. The (n, $\\gamma$) reaction in the s-process branching point $^{59}$Ni

    CERN Multimedia

    We propose to measure the $^{59}$Ni(n,$\\gamma$)$^{56}$Fe cross section at the neutron time of flight (n TOF) facility with a dedicated chemical vapor deposition (CVD) diamond detector. The (n, ) reaction in the radioactive $^{59}$Ni is of relevance in nuclear astrophysics as it can be seen as a rst branching point in the astrophysical s-process. Its relevance in nuclear technology is especially related to material embrittlement in stainless steel. There is a strong discrepancy between available experimental data and the evaluated nuclear data les for this isotope. The aim of the measurement is to clarify this disagreement. The clear energy separation of the reaction products of neutron induced reactions in $^{59}$Ni makes it a very suitable candidate for a rst cross section measurement with the CVD diamond detector, which should serve in the future for similar measurements at n_TOF.

  18. The Black Hole in the Most Massive Ultracompact Dwarf Galaxy M59-UCD3

    Science.gov (United States)

    Ahn, Christopher P.; Seth, Anil C.; Cappellari, Michele; Krajnović, Davor; Strader, Jay; Voggel, Karina T.; Walsh, Jonelle L.; Bahramian, Arash; Baumgardt, Holger; Brodie, Jean; Chilingarian, Igor; Chomiuk, Laura; den Brok, Mark; Frank, Matthias; Hilker, Michael; McDermid, Richard M.; Mieske, Steffen; Neumayer, Nadine; Nguyen, Dieu D.; Pechetti, Renuka; Romanowsky, Aaron J.; Spitler, Lee

    2018-05-01

    We examine the internal properties of the most massive ultracompact dwarf galaxy (UCD), M59-UCD3, by combining adaptive-optics-assisted near-IR integral field spectroscopy from Gemini/NIFS and Hubble Space Telescope (HST) imaging. We use the multiband HST imaging to create a mass model that suggests and accounts for the presence of multiple stellar populations and structural components. We combine these mass models with kinematics measurements from Gemini/NIFS to find a best-fit stellar mass-to-light ratio (M/L) and black hole (BH) mass using Jeans anisotropic models (JAMs), axisymmetric Schwarzschild models, and triaxial Schwarzschild models. The best-fit parameters in the JAM and axisymmetric Schwarzschild models have BHs between 2.5 and 5.9 million solar masses. The triaxial Schwarzschild models point toward a similar BH mass but show a minimum χ 2 at a BH mass of ∼0. Models with a BH in all three techniques provide better fits to the central V rms profiles, and thus we estimate the BH mass to be {4.2}-1.7+2.1× {10}6 M ⊙ (estimated 1σ uncertainties). We also present deep radio imaging of M59-UCD3 and two other UCDs in Virgo with dynamical BH mass measurements, and we compare these to X-ray measurements to check for consistency with the fundamental plane of BH accretion. We detect faint radio emission in M59cO but find only upper limits for M60-UCD1 and M59-UCD3 despite X-ray detections in both these sources. The BH mass and nuclear light profile of M59-UCD3 suggest that it is the tidally stripped remnant of a ∼109–1010 M ⊙ galaxy.

  19. Study of erythropoiesis with 59Fe and erythrocyte survival with 51Cr in aplastic anemia

    International Nuclear Information System (INIS)

    Avramova, D.; Karakostov, K.; Dimtrov, L.; Osmanliev, P.

    1979-01-01

    A study of erythropoiesis with 59 Fe and erythrocyte survival with 51 Cr was carried out in 25 patients with aplastic anemia and in a control group of 23 healthy persons. Bone marrow aplasia was uniform in all patients but differences in erythropoiesis were established. According to the state of erythropoiesis, the patients were divided into two groups: 1) patients with severe damage of erythropoiesis and 2) patients with preserved erythropoiesis. Erythrocyte survival in both groups was shortened. The data obtained correlate with the anemic syndrome and help to explain its pathogenesis. It is suggested that the investigation of erythropoiesis with 59 Fe and 51 Cr is of prognostic value. (author)

  20. Supplemental site inspection for Air Force Plant 59, Johnson City, New York, Volume 1: Investigation report

    Energy Technology Data Exchange (ETDEWEB)

    Nashold, B.; Rosenblatt, D.; Hau, J. [and others

    1995-08-01

    This summary describes a Supplemental Site Inspection (SSI) conducted by Argonne National Laboratory (ANL) at Air Force Plant 59 (AFP 59) in Johnson City, New York. All required data pertaining to this project were entered by ANL into the Air Force-wide Installation Restoration Program Information System (IRPIMS) computer format and submitted to an appropriate authority. The work was sponsored by the United States Air Force as part of its Installation Restoration Program (IRP). Previous studies had revealed the presence of contaminants at the site and identified several potential contaminant sources. Argonne`s study was conducted to answer questions raised by earlier investigations.

  1. 38 CFR 59.40 - Maximum number of nursing home care and domiciliary care beds for veterans by State.

    Science.gov (United States)

    2010-07-01

    ... home care and domiciliary care beds for veterans by State. 59.40 Section 59.40 Pensions, Bonuses, and... ACQUISITION OF STATE HOMES § 59.40 Maximum number of nursing home care and domiciliary care beds for veterans... projection of demand for nursing home and domiciliary care by veterans who at such time are 65 years of age...

  2. 42 CFR 60.59 - Records and Federal access after a school is no longer a HEAL school.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Records and Federal access after a school is no longer a HEAL school. 60.59 Section 60.59 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS HEALTH EDUCATION ASSISTANCE LOAN PROGRAM The School § 60.59 Records and Federal...

  3. 40 CFR 59.506 - How do I demonstrate compliance if I manufacture multi-component kits?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false How do I demonstrate compliance if I manufacture multi-component kits? 59.506 Section 59.506 Protection of Environment ENVIRONMENTAL PROTECTION... § 59.506 How do I demonstrate compliance if I manufacture multi-component kits? (a) If you manufacture...

  4. 49 CFR 1.59a - Redelegations by the Assistant Secretary for Administration.

    Science.gov (United States)

    2010-10-01

    ... DELEGATION OF POWERS AND DUTIES Delegations § 1.59a Redelegations by the Assistant Secretary for...-delegate and authorize successive re-delegations. (b) The Assistant Secretary for Administration has... employees under the Federal Wage System, except as delegated to the Commandant of the Coast Guard at § 1.46...

  5. Begonia semperflorens FB08-59 and FB08-163 clonal germplasm

    Science.gov (United States)

    FB08-59 is a dark-foliage, red-flowered wax begonia clone adapted to hot humid summers. It is the product of a recurrent selection breeding procedure to combine and improve the environmental tolerances identified in B. semperflorens ’Kaylen’ and B. cucullata arenosicola into a dark-foliaged, perenn...

  6. Draft Genome Sequence of the Putrescine-Producing Strain Lactococcus lactis subsp. lactis 1AA59

    Science.gov (United States)

    del Rio, Beatriz; Linares, Daniel M.; Fernandez, María; Mayo, Baltasar; Martín, M. Cruz

    2015-01-01

    We report here the 2,576,542-bp genome annotated draft assembly sequence of Lactococcus lactis subsp. lactis 1AA59. This strain—isolated from a traditional cheese—produces putrescine, one of the most frequently biogenic amines found in dairy products. PMID:26089428

  7. 216-Day report for Tank 241-C-111, cores 58 and 59

    International Nuclear Information System (INIS)

    Rice, A.D.

    1994-01-01

    Three core samples from tank C-111, and a field blank, were received by the 222-S laboratories. Cores 58, 59, and the field blank were analyzed in accordance with plans. A hot cell blank was analyzed at the direction of the hot cell chemist. No sample results exceeded the notification limits. Core 60 was not analyzed

  8. 47 CFR 59.2 - Terms and conditions of infrastructure sharing.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Terms and conditions of infrastructure sharing... SERVICES (CONTINUED) INFRASTRUCTURE SHARING § 59.2 Terms and conditions of infrastructure sharing. (a) An... carrier to fully benefit from the economies of scale and scope of such local exchange carrier. An...

  9. Decolorization and degradation of daunomycin by bjerkandera adusta R59 strain

    Energy Technology Data Exchange (ETDEWEB)

    Cho, N.S.; Belearz, A.; Ginalska, G.; Kornillowicz, K.; Cho, H.Y.; Ohga, S. [Kyushu University, Fukuoka (Japan)

    2009-02-15

    The ability of Bjerkandera adusta R59 strain to degrade anthraquinonic antibiotic (daunomycin) points on its possible aptitudes for decomposing of other anthraquinonic derivatives, e.g. lignocellulose subunits or metabolically related lipids, present in wood. This study was performed to investigate the possibility of B. adusta, R59 to synthesize enzymes participating in decay of wood compounds (including lignin, celluloses, hemicelluloses and lipids). Geotrichum-like strain, anamorphic stadium of B. adusta, white-rot. fungus, was isolated from soil. It was found to completely decolorize and degrade 10% daunomycin post-production effluent during 10 days of incubation at 26{sup o}C. R59 strain produces only small activities of lignolytic enzymes when grown on wheat straw or beech sawdust-containing media but in the presence of humic acids derived from brown coal synthesizes significant activities of laccase and lipase. This phenomenon was coupled with entering the idiophase by this fungus and appearance of aerial mycelium. The ability of B. adusta R59 strain to degrade humic acids from brown coal could be useful in constructing of new generation of biologically active filters for purification of humic acids-contaminated comestible waters.

  10. 7 CFR 59.103 - Mandatory weekly reporting for steers and heifers.

    Science.gov (United States)

    2010-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) LIVESTOCK MANDATORY REPORTING Cattle Reporting § 59.103 Mandatory weekly reporting for steers and...

  11. 7 CFR 59.101 - Mandatory daily reporting for steers and heifers.

    Science.gov (United States)

    2010-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) LIVESTOCK MANDATORY REPORTING Cattle Reporting § 59.101 Mandatory daily reporting for steers and...

  12. 7 CFR 59.400 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Science.gov (United States)

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) LIVESTOCK MANDATORY REPORTING OMB Control Number § 59.400 OMB control number...

  13. 42 CFR 59.4 - How does one apply for a family planning services grant?

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false How does one apply for a family planning services... GRANTS GRANTS FOR FAMILY PLANNING SERVICES Project Grants for Family Planning Services § 59.4 How does one apply for a family planning services grant? (a) Application for a grant under this subpart shall...

  14. 42 CFR 59.3 - Who is eligible to apply for a family planning services grant?

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Who is eligible to apply for a family planning... SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Project Grants for Family Planning Services § 59.3 Who is eligible to apply for a family planning services grant? Any public or nonprofit private entity in...

  15. 37 CFR 11.59 - Dissemination of disciplinary and other information.

    Science.gov (United States)

    2010-07-01

    ... imposed, the OED Director shall cause a final decision of the USPTO Director to be published. Final... imposed, the OED Director shall cause a redacted version of the final decision to be published. (b..., Investigations, and Proceedings § 11.59 Dissemination of disciplinary and other information. (a) The OED Director...

  16. 7 CFR 59.303 - Mandatory reporting of lamb carcasses and boxed lamb.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Mandatory reporting of lamb carcasses and boxed lamb... INSPECTION ACT (CONTINUED) LIVESTOCK MANDATORY REPORTING Lamb Reporting § 59.303 Mandatory reporting of lamb carcasses and boxed lamb. (a) Daily reporting of lamb carcass transactions. The corporate officers or...

  17. The clinical usefulness of NP-59 scintigraphy in adrenal cortical diseases

    International Nuclear Information System (INIS)

    Kim, Duk Kyu

    1997-01-01

    131 I-6-β-iodomethyl-19-norcholesterol (NP-59) has an advantage to assess adrenal dysfunction caused by adrenal cortical disorders. The aim of this study is to evaluate the clinical usefulness of NP-59 scintigraphy in each adrenal disease. Ten patients who did eleven NP-59 adrenal scintigraphies at Dong-A University Hospital from March 1990 to December 1996 were selected as the subject. Among the subject there were 5 cases of Cushing's syndrome, 2 cases of incidentaloma, 1 case of metastatic adrenal tumor, liver cirrhosis with hirsutism and hypertension respectively. Among 5 cases of Cushing's syndrome, there were 2 cases of Cushing's disease, 2 cases of adrenal adenoma and 1 case of adrenal carcinoma. There are no disagreement between clinical diagnosis and scan finding in Cushing's syndrome. In 2 incidentaloma cases, even though one is interpretated as a functioning tumor, both of 2 cases could avoid unnecessary biopsy according to scintigraphy result. One case of hirsutism, clinically adrenal originated, revealed the normal scintigraphic finding after dexamethasone suppression scan. It could suggest that the etiology of hirsutism was extra-adrenal origin. One case of hypertension took the study to exclude the possibility of primary aldosteronism. Normal suppression scan finding revealed that primary aldosteronism did not exist in this case. In conclusion, NP-59 scintigraphy was very useful in diagnosis and differential diagnosis of Cushing's syndrome and it could avoid unnecessary biopsy in the incidental adrenal tumor

  18. Temperature-Sensitive Mutants of Mouse Hepatitis Virus Strain A59: Isolation, Characterization and Neuropathogenic Properties.

    NARCIS (Netherlands)

    M.J.M. Koolen (Marck); A.D.M.E. Osterhaus (Albert); G. van Steenis (Bert); M.C. Horzinek; B.A.M. van der Zeijst (Ben)

    1983-01-01

    textabstractTwenty 5-fluorouracil-induced temperature-sensitive (ts) mutants of mouse hepatitis virus strain A59 were isolated from 1284 virus clones. Mutants were preselected on the basis of their inability to induce syncytia in infected cells at the restrictive temperature (40 degrees) vs the

  19. 46 CFR 59.15-5 - Stayed furnaces and combustion chambers.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Stayed furnaces and combustion chambers. 59.15-5 Section... and combustion chambers. (a) Where the plate forming the walls of stayed furnaces or combustion... wall of a stayed furnace or combustion chamber, the defective portion of the plate shall be cut away...

  20. 14 CFR 61.59 - Falsification, reproduction, or alteration of applications, certificates, logbooks, reports, or...

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Falsification, reproduction, or alteration...: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS General § 61.59 Falsification, reproduction, or... authorization under this part; (3) Any reproduction for fraudulent purpose of any certificate, rating, or...

  1. 7 CFR 319.59-3 - Articles prohibited importation pending risk evaluation.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Articles prohibited importation pending risk... Diseases § 319.59-3 Articles prohibited importation pending risk evaluation. The articles listed in...(b), pending the completion of an evaluation by APHIS of the potential pest risks associated with the...

  2. 46 CFR 52.01-105 - Piping, valves and fittings (modifies PG-58 and PG-59).

    Science.gov (United States)

    2010-10-01

    ... other suitable means employed to reduce the effects of metal temperature differentials. (e) Blowoff...-59). (a) Boiler external piping within the jurisdiction of the ASME Boiler and Pressure Vessel Code... and Pressure Vessel Code, boiler external piping must: (1) Meet the design conditions and criteria in...

  3. The clinical usefulness of NP-59 scintigraphy in adrenal cortical diseases

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Duk Kyu [College of Medicine, Donga Univ., Pusan (Korea, Republic of)

    1997-03-01

    {sup 131}I-6-{beta}-iodomethyl-19-norcholesterol (NP-59) has an advantage to assess adrenal dysfunction caused by adrenal cortical disorders. The aim of this study is to evaluate the clinical usefulness of NP-59 scintigraphy in each adrenal disease. Ten patients who did eleven NP-59 adrenal scintigraphies at Dong-A University Hospital from March 1990 to December 1996 were selected as the subject. Among the subject there were 5 cases of Cushing's syndrome, 2 cases of incidentaloma, 1 case of metastatic adrenal tumor, liver cirrhosis with hirsutism and hypertension respectively. Among 5 cases of Cushing's syndrome, there were 2 cases of Cushing's disease, 2 cases of adrenal adenoma and 1 case of adrenal carcinoma. There are no disagreement between clinical diagnosis and scan finding in Cushing's syndrome. In 2 incidentaloma cases, even though one is interpretated as a functioning tumor, both of 2 cases could avoid unnecessary biopsy according to scintigraphy result. One case of hirsutism, clinically adrenal originated, revealed the normal scintigraphic finding after dexamethasone suppression scan. It could suggest that the etiology of hirsutism was extra-adrenal origin. One case of hypertension took the study to exclude the possibility of primary aldosteronism. Normal suppression scan finding revealed that primary aldosteronism did not exist in this case. In conclusion, NP-59 scintigraphy was very useful in diagnosis and differential diagnosis of Cushing's syndrome and it could avoid unnecessary biopsy in the incidental adrenal tumor.

  4. Uncertainty-driven nuclear data evaluation including thermal (n,α) applied to 59Ni

    Science.gov (United States)

    Helgesson, P.; Sjöstrand, H.; Rochman, D.

    2017-11-01

    This paper presents a novel approach to the evaluation of nuclear data (ND), combining experimental data for thermal cross sections with resonance parameters and nuclear reaction modeling. The method involves sampling of various uncertain parameters, in particular uncertain components in experimental setups, and provides extensive covariance information, including consistent cross-channel correlations over the whole energy spectrum. The method is developed for, and applied to, 59Ni, but may be used as a whole, or in part, for other nuclides. 59Ni is particularly interesting since a substantial amount of 59Ni is produced in thermal nuclear reactors by neutron capture in 58Ni and since it has a non-threshold (n,α) cross section. Therefore, 59Ni gives a very important contribution to the helium production in stainless steel in a thermal reactor. However, current evaluated ND libraries contain old information for 59Ni, without any uncertainty information. The work includes a study of thermal cross section experiments and a novel combination of this experimental information, giving the full multivariate distribution of the thermal cross sections. In particular, the thermal (n,α) cross section is found to be 12.7 ± . 7 b. This is consistent with, but yet different from, current established values. Further, the distribution of thermal cross sections is combined with reported resonance parameters, and with TENDL-2015 data, to provide full random ENDF files; all of this is done in a novel way, keeping uncertainties and correlations in mind. The random files are also condensed into one single ENDF file with covariance information, which is now part of a beta version of JEFF 3.3. Finally, the random ENDF files have been processed and used in an MCNP model to study the helium production in stainless steel. The increase in the (n,α) rate due to 59Ni compared to fresh stainless steel is found to be a factor of 5.2 at a certain time in the reactor vessel, with a relative

  5. The Nucleus 59Cu. Complex Structure, Shape Evolution, Exotic Decay Modes

    International Nuclear Information System (INIS)

    Andreoiu, Corina

    2002-08-01

    High-spin states in the mass A∼60 region were populated using the state-of-art γ-ray spectrometers Gammasphere, Euroball, and GASP in conjunction with dedicated ancillary detectors. In particular, the 59 Cu nucleus was studied in several experiments, and a very extensive level scheme was determined. It comprises more than 320 transitions connecting about 150 excited states. Relative to mass, it is the most extensive level scheme known to date. Next to the spherical states at low excitation energy eight regular sequences of high-energy γ-ray transitions have been observed. They form rotational bands with various degree of deformation, which are interpreted in the light of the shell model and the configuration-dependent Cranked Nilsson-Strutinsky approach. One of the experiments was dedicated to the study of prompt particle decays. It revealed five prompt proton decays connecting five deformed states in three of the rotational bands in 59 Cu with three spherical states in the daughter nucleus 58 Ni. It is the first observation of the fine structure of the newly discovered prompt proton decay mode. The proton decays compete with the γ decay-out from the second minimum of the nuclear potential into the low-spin spherical states in the first minimum of the potential. The discrete γ decay-out mechanism of the yrast superdeformed band is investigated in detail. The nucleus 59 Zn, the mirror partner of 59 Cu, was identified for the first time, and the mirror symmetry of the T=1/2 A=59 pair is discussed

  6. Surgical support of Operation Sea Signal: adaptability of the 59th Air Transportable Hospital in Cuba.

    Science.gov (United States)

    Pelton, Jeffrey J; Buehrer, Jeffrey L; Cull, David L

    2003-12-01

    The attempted migration of approximately 50,000 Cubans in the summer of 1994 created a large patient population detained at Guantanamo Bay, Cuba. This study examined the roles and results of the 59th Air Transportable Hospital (ATH) in treating surgical problems within that population during Operation Sea Signal. The surgical case log of the 59th ATH was used to identify all patients operated on at the 59th ATH during the interval of August 1994 to April 1995. These case records and the individual records of the three 59th ATH surgeons were used to determine the types of cases performed, complications, and outcomes. A total of 333 operations were performed at the 59th ATH in three types of surgery: (1) elective (267); (2) emergency for nonself-inflicted conditions (46); and (3) emergency for self-inflicted conditions (20). The total perioperative complication rate was 2.4% (8/333), and the wound infection rate for clean surgical cases was 0.87% (2/229). Elective surgery may be performed in a field environment with acceptable complication and wound infection rates. Humanitarian missions will be faced with considerable pathology from pre-existing conditions within the population cared for. The humanitarian mission may be complicated by political situations that may encourage malingering and self-injurious behavior within the population cared for. The latter events have not been previously encountered in humanitarian missions involving the U.S. military and must be considered by policy makers and mission planners in planning future humanitarian missions.

  7. Uptake, distribution, and incorporation of 59Fe in tissue and blood of rainbow trout (Salmo gairdneri)

    International Nuclear Information System (INIS)

    Walker, R.L.

    1975-01-01

    A study was designed to evaluate the storage iron facilities in various tissues and to trace the distribution of radioiron in tissues and blood following an intraperitoneal (i.p.) injection of 59 Fe. Iron deficiency anemia was induced in an experimental group of rainbow trout in order to measure its effect on red blood cell production and mobilization of storage iron. Most of the 59 Fe was absorbed from the peritoneal cavity within 24 hrs. after the i.p. injection. Equilibrium between the plasma 59 Fe pool and that of the tissue was established by day 8. Experimental fish RBC 59 Fe content increased to 70 to 80 percent of the initial injected dose by day 16 compared to 50 percent in the controls. This was attributed to the difference in reticulocyte count which was 10 to 12 percent for the bled and 2 to 3 percent for control fish. The rate that iron is incorporated into hemoglobin by immature red cells is much slower (about half) than the rate of RBC 59 Fe uptake, thus, iron is temporarily stored in the cytoplasm. The iron for hemoglobin formation was obtained from liver iron stores which dropped from 12 percent to less than 1 percent of the initial injected dose by day 16. Total iron concentration in liver decreased from 200 to less than 100 μg Fe/g. The decrease in liver iron may have stimulated iron absorption by the intestine and pyloric caeca. There is evidence for a feedback mechanism mediated by transferrin

  8. The mechanism of action of MF59 - an innately attractive adjuvant formulation.

    Science.gov (United States)

    O'Hagan, D T; Ott, G S; De Gregorio, E; Seubert, A

    2012-06-19

    MF59 is a safe and effective vaccine adjuvant which was originally approved to be included in a licensed influenza vaccine to be used in the elderly in Europe in 1997. The MF59 adjuvanted influenza vaccine (Fluad™) is now licensed in more than 20 countries worldwide and more than 85 million doses have been administered. More recently the vaccine adjuvant has also been shown to be safe and effective in young children and resulted in a significant increase in influenza vaccine efficacy in a controlled clinical trial in Europe. Since the early days of its discovery we have explored the mechanism of action of MF59, using a variety of available techniques. In recent years we have explored more thoroughly the mechanism of action using new and more sophisticated techniques. It is remarkable how consistent the data has been, using a variety of different approaches both in several small animal models and also using human immune cells in vitro. Here we present a summary of all the work performed to date on the mechanism of action of MF59 and we present a unified theory based on the accumulated data of how it exerts its adjuvant effects. A key element of the mechanism of action appears to be the creation of a transient 'immunocompetent' local environment at the injection site, resulting in the recruitment of key immune cells, which are able to take up antigen and adjuvant and transport them to the local lymph nodes, where the immune response is induced. This recruitment appears to be triggered by the induction of a chemokine driven gradient by the impact of MF59 on local cells, which are activated to secrete further chemokines, which are recruitment factors for more immune cells. Copyright © 2011 Elsevier Ltd. All rights reserved.

  9. Iron and zinc concentrations and 59Fe retention in developing fetuses of zinc-deficient rats

    International Nuclear Information System (INIS)

    Rogers, J.M.; Loennerdal, B.H.; Hurley, L.S.; Keen, C.L.

    1987-01-01

    Because disturbances in iron metabolism might contribute to the teratogenicity of zinc deficiency, we examined the effect of zinc deficiency on fetal iron accumulation and maternal and fetal retention of 59 Fe. Pregnant rats were fed from mating a purified diet containing 0.5, 4.5 or 100 micrograms Zn/g. Laparotomies were performed on d 12, 16, 19 and 21 of gestation. Maternal blood and concepti were analyzed for zinc and iron. Additional groups of dams fed 0.5 or 100 micrograms Zn/g diet were gavaged on d 19 with a diet containing 59 Fe. Six hours later maternal blood and tissues, fetuses and placentas were counted for 59 Fe. Maternal plasma zinc, but not iron, concentration was affected by zinc deficiency on d 12. Embryo zinc concentration on d 12 increased with increasing maternal dietary zinc, whereas iron concentration was not different among groups. On d 16-21 plasma iron was higher in dams fed 0.5 micrograms Zn/g diet than in those fed 4.5 or 100 micrograms/g, whereas plasma zinc was lower in dams fed 0.5 or 4.5 micrograms Zn/g than in those fed 100 micrograms Zn/g diet. On d 19 zinc concentration in fetuses from dams fed 0.5 micrograms/g zinc was not different from that of those fed 4.5 micrograms/g zinc, and iron concentration was higher in the 0.5 microgram Zn/g diet group. The increase in iron concentration in zinc-deficient fetuses thus occurs too late to be involved in major structural teratogenesis. Although whole blood concentration of 59 Fe was not different in zinc-deficient and control dams, zinc-deficient dams had more 59 Fe in the plasma fraction

  10. Gamma-ray mutagenesis studies in a new human-hamster hybrid, A(L)CD59(+/-), which has two human chromosomes 11 but is hemizygous for the CD59 gene

    Science.gov (United States)

    Kraemer, S. M.; Vannais, D. B.; Kronenberg, A.; Ueno, A.; Waldren, C. A.; Chatterjee, A. (Principal Investigator)

    2001-01-01

    Kraemer, S. M., Vannais, D. B., Kronenberg, A., Ueno, A. and Waldren, C. A. Gamma-Ray Mutagenesis Studies in a New Human-Hamster Hybrid, A(L)CD59(+/-), which has Two Human Chromosomes 11 but is Hemizygous for the CD59 Gene. Radiat. Res. 156, 10-19 (2001).We have developed a human-CHO hybrid cell line, named A(L)CD59(+/-), which has two copies of human chromosome 11 but is hemizygous for the CD59 gene and the CD59 cell surface antigen that it encodes. Our previous studies used the A(L) and A(L)C hybrids that respectively contain one or two sets of CHO chromosomes plus a single copy of human chromosome 11. The CD59 gene at 11p13.5 and the CD59 antigen encoded by it are the principal markers used in our mutagenesis studies. The hybrid A(L)CD59(+/-) contains two copies of human chromosome 11, only one of which carries the CD59 gene. The incidence of CD59 (-) mutants (formerly called S1(-)) induced by (137)Cs gamma rays is about fivefold greater in A(L)CD59(+/-) cells than in A(L) cells. Evidence is presented that this increase in mutant yield is due to the increased induction of certain classes of large chromosomal mutations that are lethal to A(L) cells but are tolerated in the A(L)CD59(+/-) hybrid. In addition, significantly more of the CD59 (-) mutants induced by (137)Cs gamma rays in A(L)CD59(+/-) cells display chromosomal instability than in A(L) cells. On the other hand, the yield of gamma-ray-induced CD59 (-) mutants in A(L)CD59(+/-) cells is half that of the A(L)C hybrid, which also tolerates very large mutations but has only one copy of human chromosome 11. We interpret the difference in mutability as evidence that repair processes involving the homologous chromosomes 11 play a role in determining mutant yields. The A(L)CD59(+/-) hybrid provides a useful new tool for quantifying mutagenesis and shedding light on mechanisms of genetic instability and mutagenesis.

  11. Metallofullerenes as fuel cell electrocatalysts: a theoretical investigation of adsorbates on C59Pt.

    Science.gov (United States)

    Gabriel, Margaret A; Genovese, Luigi; Krosnicki, Guillaume; Lemaire, Olivier; Deutsch, Thierry; Franco, Alejandro A

    2010-08-28

    Nano-structured electrode degradation in state-of-the-art polymer electrolyte membrane fuel cells (PEMFCs) is one of the main shortcomings that limit the large-scale development and commercialization of this technology. During normal operating conditions of the fuel cell, the PEMFC lifetime tends to be limited by coarsening of the cathode's Pt-based catalyst and by corrosion of the cathode's carbon black support. Because of their chemical properties, metallofullerenes such as C(59)Pt may be more electrochemically stable than the Pt/C mixture. In this paper we investigate, by theoretical methods, the stability of oxygen reduction reaction (ORR) adsorbates on the metallofullerene C(59)Pt and evaluate its potential as a PEMFC fuel cell catalyst.

  12. Structural variation study of cobalt nanoparticles synthesized by co-precipitation method using 59Co NMR

    Science.gov (United States)

    Manjunatha, M.; Kumar, Rajeev; B. M., Siddesh; Sahoo, Balaram; Damle, R.; Ramesh, K. P.

    2018-04-01

    We have synthesized cobalt nanoparticles using co-precipitation method. Further, the two phases of the cobalt is monitored by varying the synthesis parameters. 59Co NMR and XRD are used as characterization tools to study the phase variation in the cobalt samples. XRD and NMR results show a remarkable correlation in the two samples (Co-1 and Co-2). Co-2 has predominant fcc and hcp phases, whereas, Co-1 has fcc phase with lower amount of hcp. Both the samples show same saturation magnetization (Ms) but there is a remarkable difference in the phase composition. Thus, 59Co NMR appears to be a good tool to identify the phase purity of the ferromagnetic cobalt samples.

  13. Radiation absorbed doses from iron-52, iron-55, and iron-59 used to study ferrokinetics

    International Nuclear Information System (INIS)

    Robertson, J.S.; Price, R.R.; Budinger, T.F.; Fairbanks, V.F.; Pollycove, M.

    1983-01-01

    Biological data obtained principally with Fe-59 citrate are used with physical data to calculate radiation absorbed doses for ionic or weak chelate forms of Fe-52, Fe-55, and Fe-59, administered by intravenous injection. Doses are calculated for normal subjects, primary hemochromatosis (also called idiopathic or hereditary hemochromatosis), pernicious anemia in relapse, iron-deficiency anemia, and polycythemia vera. The Fe-52 doses include the dose from the Mn-52m daughter generated after injection of Fe-52. Special attention has been given to the dose to the spleen, which has a relatively high concentration of RBCs and therefore of radioiron, and which varies significantly in size in both health and disease

  14. Cummins Engine Company B5.9 Propane Engine Development, Certification, and Demonstration Project

    Energy Technology Data Exchange (ETDEWEB)

    The ADEPT Group, Inc. (Los Angeles, California)

    1998-12-18

    The objective of this project was to successfuly develop and certify an LPG-dedicated medium-duty original equipment manufacturer (OEM) engine that could be put into production. The engine was launched into production in 1994, and more than 800 B5.9G engines are now in service in the United States and abroad. This engine is now offered by more than 30 bus and truck OEMs.

  15. Polarized neutron capture in polarized 59Co and 165Ho nuclei

    International Nuclear Information System (INIS)

    Bosman, J.J.

    1976-01-01

    Gamma spectroscopy on the reactions 59 Co(n,γ) 60 Co and 165 Ho(n,γ) 166 Ho with polarized neutrons and polarized targets enabled the assignment of spins to 36 levels in 60 Co and 15 levels in 166 Ho. Several of them had not been reported earlier. The techniques used to polarize neutron beams and targets and the gamma-spectroscopy are extensively discussed

  16. Structural Characterization of Monomeric/Dimeric State of p59fyn SH2 Domain.

    Science.gov (United States)

    Huculeci, Radu; Kieken, Fabien; Garcia-Pino, Abel; Buts, Lieven; van Nuland, Nico; Lenaerts, Tom

    2017-01-01

    Src homology 2 (SH2) domains are key modulators in various signaling pathways allowing the recognition of phosphotyrosine sites of different proteins. Despite the fact that SH2 domains acquire their biological functions in a monomeric state, a multitude of reports have shown their tendency to dimerize. Here, we provide a technical description on how to isolate and characterize by gel filtration, circular dichroism (CD), and nuclear magnetic resonance (NMR) each conformational state of p59 fyn SH2 domain.

  17. Social Costs of Iron Deficiency Anemia in 6-59-Month-Old Children in India.

    Science.gov (United States)

    Plessow, Rafael; Arora, Narendra Kumar; Brunner, Beatrice; Tzogiou, Christina; Eichler, Klaus; Brügger, Urs; Wieser, Simon

    2015-01-01

    Inadequate nutrition has a severe impact on health in India. According to the WHO, iron deficiency is the single most important nutritional risk factor in India, accounting for more than 3% of all disability-adjusted life years (DALYs) lost. We estimate the social costs of iron deficiency anemia (IDA) in 6-59-month-old children in India in terms of intangible costs and production losses. We build a health economic model estimating the life-time costs of a birth cohort suffering from IDA between the ages of 6 and 59 months. The model is stratified by 2 age groups (6-23 and 24-59-months), 2 geographical areas (urban and rural), 10 socio-economic strata and 3 degrees of severity of IDA (mild, moderate and severe). Prevalence of anemia is calculated with the last available National Family Health Survey. Information on the health consequences of IDA is extracted from the literature. IDA prevalence is 49.5% in 6-23-month-old and 39.9% in 24-58-month-old children. Children living in poor households in rural areas are particularly affected but prevalence is high even in wealthy urban households. The estimated yearly costs of IDA in 6-59-month-old children amount to intangible costs of 8.3 m DALYs and production losses of 24,001 m USD, equal to 1.3% of gross domestic product. Previous calculations have considerably underestimated the intangible costs of IDA as the improved WHO methodology leads to a threefold increase of DALYs due to IDA. Despite years of iron supplementation programs and substantial economic growth, IDA remains a crucial public health issue in India and an obstacle to the economic advancement of the poor. Young children are especially vulnerable due to the irreversible effects of IDA on cognitive development. Our research may contribute to the design of new effective interventions aiming to reduce IDA in early childhood.

  18. Prevalence of anemia in children 6-59 months old in the state of Pernambuco, Brazil

    Directory of Open Access Journals (Sweden)

    Mônica M. Osório

    2001-08-01

    Full Text Available Objective. To determine the prevalence of anemia in children 6-59 months old in Pernambuco, a state in northeastern Brazil, so as to help guide health and nutrition policies there. Methods. In 1997 a representative sample of 777 young children had their hemoglobin concentration measured. The sampling process was in three stages. First, 18 municipalities were randomly selected to represent the state and its three geographic areas (metropolitan region of Recife, urban interior, and rural interior. Next, using census lists, 45 census sectors were randomly chosen. Finally, 777 children aged 6-59 months old were selected. Blood was collected by venipuncture, and hemoglobin was measured with a portable hemoglobinometer. In the analysis, prevalence was weighted to reflect the census age distribution. Results. The prevalence of anemia among children 6-59 months old was 40.9% for the state as a whole. Prevalence in the metropolitan region of Recife was 39.6%, and it was 35.9% in the urban interior. The rural interior had the highest prevalence, 51.4%. Prevalence was twice as high in children aged 6-23 months as among those 24-59 months old, 61.8% vs. 31.0% (chi² = 77.9, P < 0.001. The mean hemoglobin concentrations in the younger and older age groups were 10.4 g/dL (standard deviation (SD = 1.5 and 11.4 g/dL (SD = 1.4, respectively. There was no statistically significant difference between the sexes in terms of prevalence. Conclusions. This is the first statewide assessment of anemia prevalence among young children in Brazil. Given the very high prevalence of anemia among the children studied in Pernambuco, especially those in the age group of 6-23 months, public health interventions are needed.

  19. Whole-body iron-59 retention measurements for estimating the iron status of piglets

    International Nuclear Information System (INIS)

    Pfau, A.; Rudolphi, K.; Heinrich, H.C.; Gabbe, E.E.

    1976-01-01

    A large-volume, 4π whole-body liquid scintillation detector was used to determine 59 Fe absorption in 173 one-to-six-weeks-old piglets with normal and depleted iron stores. Values of intestinal absorption from a 10 μmole (corresponds to 0.558 mg) 59 Fe 2+ test dose were compared with levels of haemoglobin, haematocrit, and serum iron as well as with stainable diffuse iron of bone marrow reticuloendothelial cells, and the dose relationship of intestinal iron absorption from 59 Fe-labelled FeSO 4 and methaemoglobin was measured. The investigations indicated that neither blood parameters, cytochemical gradings nor absorption levels from the 59 Fe test dose alone were sufficient to describe quantitatively the various stages of iron deficiency in piglets. A synopsis of all parameters appeared to be necessary for defining normal iron status and prelatent, latent and manifest iron deficiency. Piglets fed on sows' milk only developed manifest iron deficiency within the first three weeks of age. After an access to soil and/or creep feed from the eighth day of age, or intramuscular injections of 200 mg Fe as iron-dextran at three days of age, or injections of 200 or 400 mg Fe combined with access to creep feed, stages of manifest, latent or prelatent iron deficiency could be observed. For an iron-dextran dose of 800 mg Fe injected in amounts of 400 mg Fe at 3 and 10 days of age, a normal iron status was obtained in three-week-old piglets. The iron dose relationship indicated that 20 mg Fe administered orally as FeSO 4 or 40 mg Fe as methaemoglobin-Fe daily should cover the iron requirement of piglets for the first three weeks of life, whereas a three-week total of iron given orally in a single dose would lead to unphysiological or fatal conditions in nursing pigs. (author)

  20. Accelerator mass spectrometry of 59Ni and Fe isotopes at the Argonne superconducting linac

    International Nuclear Information System (INIS)

    Henning, W.; Kutschera, W.; Myslek-Laurikainen, B.; Pardo, R.C.; Smither, R.K.; Yntema, J.L.

    1981-01-01

    We have obtained initial results in an attempt to use the Argonne tandem-linac system for accelerator mass spectrometry of medium-heavy nuclei. Nuclei of the radioisotope 59 Ni (T/sub 1/2 = 7.5 x 10 5 y) and of the stable isotope 58 Fe at low concentrations have been accelerated and clearly identified. The latter experiment is in preparation of a measurement of the half-life of 60 Fe

  1. Thermal capture cross section for 58Ni (n,γ)59 Ni reaction

    International Nuclear Information System (INIS)

    Carbonari, A.W.; Pecequilo, B.R.S.

    1989-01-01

    The 58 Ni total thermal capture cross section was determined by suming the partial cross sections calculated for the primary transitions of the reaction 58 Ni (n,γ) 59 Ni. The primary transitions energies and intensities were determined from the 58 Ni thermal neutrons prompt gamma capture gamma rays spectrum in the 3.7 to 9.3 MeV region. The obtained value for the total cross section was 4.52 + 0.10b. (author) [pt

  2. The Merger History, AGN and Dwarf Galaxies of Hickson Compact Group 59

    Science.gov (United States)

    Konstantopoulos, I. S.; Gallagher, S. C.; Fedotov, K.; Durrell, P. R.; Tzanavaris, P.; Hill, A. R.; Zabludoff, A. I.; Maier, M. L.; Elmegreen, D. M.; Charlton, J. C.; hide

    2011-01-01

    Compact group galaxies often appear unaffected by their unusually dense environment. Closer examination can, however, reveal the subtle, cumulative effects of multiple galaxy interactions. Hickson Compact Group (HCG) 59 is an excellent example of this situation. We present a photometric study of this group in the optical (HST), infrared (Spitzer) and X-ray (Chandra) regimes aimed at characterizing the star formation and nuclear activity in its constituent galaxies and intra-group medium. We associate five dwarf galaxies with the group and update the velocity dispersion, leading to an increase in the dynamical mass of the group of up to a factor of 10 (to 2.8 x 10(exp 13) Stellar Mass), and a subsequent revision of its evolutionary stage. Star formation is proceeding at a level consistent with the morphological types of the four main galaxies, of which two are star-forming and the other two quiescent. Unlike in some other compact groups, star-forming complexes across HCG 59 closely follow mass-radius scaling relations typical of nearby galaxies. In contrast, the ancient globular cluster populations in galaxies HCG 59A and B show intriguing irregularities, and two extragalactic HII regions are found just west of B. We age-date a faint stellar stream in the intra-group medium at approx. 1 Gyr to examine recent interactions. We detect a likely low-luminosity AGN in HCG 59A by its approx. 10(exp 40) erg/s X-ray emission; the active nucleus rather than star formation can account for the UV+IR SED. We discuss the implications of our findings in the context of galaxy evolution in dense environments.

  3. Program for TI programmable 59 calculator for calculation of 3H concentration of water samples

    International Nuclear Information System (INIS)

    Hussain, S.D.; Asghar, G.

    1982-09-01

    A program has been developed for TI Programmable 59 Calculator of Texas Instruments Inc. to calculate from the observed parameters such as count rate etc. the 3 H (tritium) concentration of water samples processed with/without prior electrolytic enrichment. Procedure to use the program has been described in detail. A brief description of the laboratory treatment of samples and the mathematical equations used in the calculations have been given. (orig./A.B.)

  4. ANALISIS FAKTOR YANG BERHUBUNGAN DENGAN STATUS GIZI ANAK USIA 6-59 BULAN

    Directory of Open Access Journals (Sweden)

    Suzanna Suzanna

    2017-01-01

    Abstrak: Analisis Faktor Yang Berhubungan Dengan Status Gizi Anak Usia 6-59 Bulan. Masalah gizi masih merupakan masalah kesehatan terutama anak balita, karena balita merupakan kelompok rawan. Penelitian bertujuan mengetahui faktor-faktor yang berhubungan dengan status gizi anak usia 6-59 bulan di Puskesmas Kecamatan Singkawang Utara Kota Singkawang. Penelitian menggunakan desain cross sectional dengan jumlah sampel 96 balita usia 6-59 bulan yang dilaksanakan bulan Maret sampai dengan Mei 2014. Teknik pengambilan sampel proporsional random sampling. Pengolahan dan analisa data menggunakan komputerisasi. Uji statistik yang digunakan uji chi square.Ha sil penelitian menunjukkan ada hubungan yang bermakna antara pendidikan ibu (p value=0,000, pengetahuan gizi ibu (p value=0,022, pola asuh (p value=0,000, penyakit infeksi (p value=0,000, asupan energi (p value=0,000 dan asupan protein (p value=0,000 dengan status gizi balita di Puskesmas Kecamatan Singkawang Utara Kota Singkawang dan tidak ada hubungan yang bermakna antara umur ibu saat hamil (p value=0,877, jumlah anak (p value=0,938 dan pola makan (p value=0,668 dengan status gizi balita.Disarankan pada ibu yang memiliki balita untuk bisa lebih meningkatkan pengetahuan melalui membaca buku menu seimbang dan media informasi seperti televisi, majalah, internet dll. Serta meningkatkan konsumsi Energi sebanyak 1600 gr/hr, Protein sebanyak 35 gr/hr (AKG, 2013.

  5. New method for simultaneous determination of 55Fe and 59Fe in blood serum samples

    International Nuclear Information System (INIS)

    Saukkonen, H.; Uhlenius, R.

    1978-01-01

    Routine methods for the measurement of 55 Fe and 59 Fe activities in biological samples are frequently required in metabolic studies of iron. A new simple method for the simultaneous determination of 59 Fe and 55 Fe concentration in 5 cm 3 samples of blood is described and carefully evaluated. Before the measurement of the activity, organic matter was eliminated by HNO 3 -HClO 4 wet ashing and iron was electroplated onto a copper plate. The accuracy of results was studied by assessing samples, which contained known amounts of radioactivity and determining the counts per nanocurie in each case. The accuracy of the results of 59 Fe and 55 Fe determinations was found to be about 5%. The method has been routinely used to determine iron resorption in patients using the double isotope method. The determination proved to be satisfactory and not too laborious. When performing the yield determination there is a way of detecting and correcting mistakes or incompleteness in different stages of the measurement, thus leading to a high degree of reliability. (T.G.)

  6. Further evidence for P59L mutation in GJA3 associated with autosomal dominant congenital cataract

    Directory of Open Access Journals (Sweden)

    Li Wang

    2016-01-01

    Full Text Available Context: Congenital cataracts are one of the common eye disorders leading to visual impairment or blindness in children worldwide. We found a Chinese family with autosomal dominant pulverulent cataract. Aims: To identify the pathogenic gene mutation in a Chinese family with autosomal dominant inherited pulverulent cataract. Subjects and Methods: After obtained informed consent, detailed ophthalmic examinations were carried out; genomic DNAs were obtained from seven family members in a three-generation Chinese family with three affected. All exons of candidate genes were amplified by polymerase chain reaction and were sequenced performed by bidirectional sequencing. Results: By sequencing the encoding regions of the candidate genes, a missense mutation (c. 176C>T was detected in gap junction protein alpha 3 genes (GJA3, which resulted in the substitution of highly conserved proline by leucine at codon 59 (p.P59L. The mutation co-segregated with all patients and was absent in 100 normal Chinese controls. Conclusions: The study identified a missense mutation (c. 176C>T in GJA3 gene associated with autosomal dominant congenital pulverulent cataract in a Chinese family. It gave further evidence of phenotype heterogeneity for P59L mutation in GJA3 associated with congenital cataract.

  7. Comparison of chromium-51 and iron-59 for estimating erythrocyte survival in the cat

    International Nuclear Information System (INIS)

    Liddle, C.G.; Putnam, J.P.; Berman, E.; Fisher, H.; Ostby, J.

    1984-01-01

    Erythrocyte survival studies were conducted on eight normal, healthy, 1-year-old male specific-pathogen-free cats using both chromium-51 and iron-59 simultaneously. The chromium-51 procedure gave a half-life value of 11.1 +/- 0.9 days. This was considerably lower than would be expected on the basis of the experimentally determined iron-59 erythrocyte survival time of 51.2 +/- 14.9 days. The results of this study indicated that there was considerable loss of the chromium-51 label in the cat other than that from senescence alone. An analysis of the chromium-51 disappearance curve indicated that there were two exponential disappearance rates for the chromium-51 label and, in the absence of cell death, approximately 67% of the label was lost with a rate constant of 0.02 per day and 33% was lost with a rate constant of 0.1 per day. An equation is presented which models the loss of chromium-51 label which could be used to calculate erythrocyte survival from a chromium-51 disappearance curve. Blood volume measurements, hemograms, bone marrow differential results, and iron kinetic values also were determined and the results presented. While a reasonable approximation of the erythrocyte life span could be made by correcting the chromium-51 values for losses other than senescence, the iron-59 procedure would be the preferred method in cats

  8. Program collaboration and service integration activities among HIV programs in 59 U.S. health departments.

    Science.gov (United States)

    Fitz Harris, Lauren F; Toledo, Lauren; Dunbar, Erica; Aquino, Gustavo A; Nesheim, Steven R

    2014-01-01

    We identified the level and type of program collaboration and service integration (PCSI) among HIV prevention programs in 59 CDC-funded health department jurisdictions. Annual progress reports (APRs) completed by all 59 health departments funded by CDC for HIV prevention activities were reviewed for collaborative and integrated activities reported by HIV programs for calendar year 2009. We identified associations between PCSI activities and funding, AIDS diagnosis rate, and organizational integration. HIV programs collaborated with other health department programs through data-related activities, provider training, and providing funding for sexually transmitted disease (STD) activities in 24 (41%), 31 (53%), and 16 (27%) jurisdictions, respectively. Of the 59 jurisdictions, 57 (97%) reported integrated HIV and STD testing at the same venue, 39 (66%) reported integrated HIV and tuberculosis testing, and 26 (44%) reported integrated HIV and viral hepatitis testing. Forty-five (76%) jurisdictions reported providing integrated education/outreach activities for HIV and at least one other disease. Twenty-six (44%) jurisdictions reported integrated partner services among HIV and STD programs. Overall, the level of PCSI activities was not associated with HIV funding, AIDS diagnoses, or organizational integration. HIV programs in health departments collaborate primarily with STD programs. Key PCSI activities include integrated testing, integrated education/outreach, and training. Future assessments are needed to evaluate PCSI activities and to identify the level of collaboration and integration among prevention programs.

  9. Consumo alimentar entre crianças brasileiras com idade de 6 a 59 meses Food consumption Brazilian children by 6 to 59 months of age

    Directory of Open Access Journals (Sweden)

    Gisele Ane Bortolini

    2012-09-01

    Full Text Available O objetivo foi avaliar o consumo alimentar em crianças brasileiras de 6-59 meses de idade, por região e zona de residência. Trata-se de estudo descritivo transversal com 4.322 crianças investigadas na Pesquisa Nacional de Demografia e Saúde (2006/2007. Observou-se baixo consumo diário de verduras (12,7%, legumes (21,8%, carnes (24,6% e elevado consumo de refrigerantes (40,5%, alimentos fritos (39,4%, salgadinhos (39,4%, doces (37,8%, na frequência de uma a três vezes na semana. Comparando-se as regiões, as crianças residentes no Sul, Sudeste e Centro-oeste consumiram com mais frequência arroz, pão, batata, feijão, verdura de folha, legumes e carne, mas também consumiram, mais frequentemente, alimentos não recomendados para a idade, como doces e refrigerantes. Crianças da zona rural apresentaram menor consumo dos alimentos recomendados para a idade e, também, dos não recomendados, quando comparadas às crianças da zona urbana. O consumo alimentar evidenciado neste estudo não está de acordo com recomendações de alimentação saudável para crianças.The aim of this study was to assess food consumption in Brazilian children 6 to 59 months of age by region of the country and area of residence. This was a descriptive cross-sectional study of 4,322 children in the National Demographic and Health Survey (2006-2007. The data showed low daily consumption of leafy vegetables (12.7%, vegetables (21.8%, and meat (24.6% and high consumption (1-3 times a week of soft drinks (40.5%, fried foods (39.4%, salty snacks (39.4%, and sweets (37.8%. Comparing the regions of Brazil, children in the South, Southeast, and Central-West consumed more rice, bread, potatoes, beans, greens, vegetables, and meat, but they also ate more foods not recommended for their age, like sweets and soft drinks (soda. Rural children showed lower consumption of foods recommended for their age and also those not recommended for their age, as compared to their urban

  10. Atomic Transition Probabilities Scandium through Manganese

    International Nuclear Information System (INIS)

    Martin, G.A.; Fuhr, J.R.; Wiese, W.L.

    1988-01-01

    Atomic transition probabilities for about 8,800 spectral lines of five iron-group elements, Sc(Z = 21) to Mn(Z = 25), are critically compiled, based on all available literature sources. The data are presented in separate tables for each element and stage of ionization and are further subdivided into allowed (i.e., electric dipole-E1) and forbidden (magnetic dipole-M1, electric quadrupole-E2, and magnetic quadrupole-M2) transitions. Within each data table the spectral lines are grouped into multiplets, which are in turn arranged according to parent configurations, transition arrays, and ascending quantum numbers. For each line the transition probability for spontaneous emission and the line strength are given, along with the spectroscopic designation, the wavelength, the statistical weights, and the energy levels of the upper and lower states. For allowed lines the absorption oscillator strength is listed, while for forbidden transitions the type of transition is identified (M1, E2, etc.). In addition, the estimated accuracy and the source are indicated. In short introductions, which precede the tables for each ion, the main justifications for the choice of the adopted data and for the accuracy rating are discussed. A general introduction contains a discussion of our method of evaluation and the principal criteria for our judgements

  11. Fast neutron scattering near shell closures: Scandium

    International Nuclear Information System (INIS)

    Smith, A.B.; Guenther, P.T.

    1992-08-01

    Neutron differential elastic- and inelastic-scattering cross sections are measured from ∼ 1.5 to 10 MeV with sufficient detail to define the energy-averaged behavior of the scattering processes. Neutrons corresponding to excitations of 465 ± 23, 737 ± 20, 1017 ± 34, 1251 ± 20, 1432 ± 23 and 1692 ± 25 keV are observed. It is shown that the observables, including the absorption cross section, are reasonably described with a conventional optical-statistical model having energy-dependent geometric parameters. These energy dependencies are alleviated when the model is extended to include the contributions of the dispersion relationship. The model parameters are conventional, with no indication of anomalous behavior of the neutron interaction with 45 Sc, five nucleons from the doubly closed shell at 40 Ca

  12. Bm59 is an early gene, but is unessential for the propagation and assembly of Bombyx mori nucleopolyhedrovirus.

    Science.gov (United States)

    Hu, Xiaolong; Shen, Yunwang; Zheng, Qin; Wang, Guobao; Wu, Xiaofeng; Gong, Chengliang

    2016-02-01

    Bombyx mori nucleopolyhedrovirus (BmNPV) is a major pathogen that specifically infects the domestic silkworm and causes serious economic loss to sericulture around the world. The function of BmNPV Bm59 gene in the viral life cycle is inconclusive. To investigate the role of Bm59 during viral infection, the transcription initiation site and temporal expression of Bm59 were analyzed, and Bm59-knockout virus was generated through homologous recombination in Escherichia coli. The results showed that Bm59 is an early transcription gene with an atypia early transcriptional start motif. Budded virion (BV) production and DNA replication in the BmN cells transfected with the Bm59-knockout virus bacmid were similar to those in the cells transfected with the wild-type virus. Electron microscopy revealed that the occlusion-derived virus can be produced in cells infected with the Bm59-knockout virus. These results indicated that Bm59 is an early gene and is not essential for viral replication or assembly of BmNPV. These findings suggested that non-essential gene (Bm59) remained in the viral genome, which may interact with other viral/host genes in a certain situation.

  13. Theoretical calculation of n + {sup 59}Co reaction in energy region up to 100 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Qingbiao, Shen; Baosheng, Yu; Dunjiu, Cai [Chinese Nuclear Data Center, Beijing, BJ (China)

    1996-06-01

    A set of neutron optical potential parameters for {sup 59}Co in energy region of 2{approx}100 MeV was obtained based on concerned experimental data. Various cross sections of n + {sup 59}Co reactions were calculated and predicted. The calculated results show that the activation products {sup 58,57}Co, {sup 59}Fe and {sup 56}Mn are main neutron monitor reaction products for n + {sup 59}Co reaction in energy range up to 100 MeV. {sup 54}Mn production reaction can be a promising neutron monitor reaction in the energy region from 30 to 100 MeV. (6 figs.).

  14. Molecular and functional characterization of CD59 from Nile tilapia (Oreochromis niloticus) involved in the immune response to Streptococcus agalactiae.

    Science.gov (United States)

    Gan, Zhen; Wang, Bei; Zhou, Wei; Lu, Yishan; Zhu, Weiwei; Tang, Jufen; Jian, JiChang; Wu, Zaohe

    2015-05-01

    CD59, the major inhibitor of membrane attack complex, plays a crucial role in regulation of complement activation. In this paper, a CD59 gene of Nile tilapia, Oreochromis niloticus (designated as On-CD59) was cloned and its expression pattern under the stimulation of Streptococcus agalactiae was investigated. Sequence analysis showed main structural features required for complement-inhibitory activity were detected in the deduced amino acid sequence of On-CD59. In healthy Nile tilapia, the On-CD59 transcripts could be detected in all the examined tissues, with the most abundant expression in the brain. When immunized with inactivated S. agalactiae, there was a clear time-dependent expression pattern of On-CD59 in the skin, brain, head kidney, thymus and spleen, with quite different kinetic expressions. The assays for the complement-inhibitory activity suggested that recombinant On-CD59 protein had a species-selective inhibition of complement. Moreover, our works showed that recombinant On-CD59 protein may possess both binding activities to PGN and LTA and inhibiting activity of S. agalactiae. These findings indicated that On-CD59 may play important roles in the immune response to S. agalactiae in Nile tilapia. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Evaluation of neutron monitor cross sections for {sup 59}Co(n,x){sup 56,57,58}Co, {sup 52,54,56}Mn, {sup 59}Fe reactions

    Energy Technology Data Exchange (ETDEWEB)

    Baosheng, Yu; Qingbiao, Shen; Dunjiu, Cai [Chinese Nuclear Data Center, Beijing, BJ (China)

    1996-06-01

    The neutron monitor cross sections for {sup 59}Co(n,x){sup 56,57,58}Co, {sup 52,54,56}Mn, {sup 59}Fe reactions were evaluated based on recent experimental data and theoretical calculations from threshold energy to 100 MeV. (8 figs.).

  16. 59. Report of Arbeitsgemeinschaft Rhein-Wasserwerke e.V. (ARW). Annual report 2002; 59. Bericht der Arbeitsgemeinschaft Rhein-Wasserwerke e.V. (ARW). Jahresbericht 2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    This annual report presents the activities of the Arbeitsgemeinschaft Rhein-Wasserwerke e.V. (ARW), important results of Rhine water monitoring, and current developments in water management. This year, a special measuring programme was jointly carried out by ARW and the Deutsche Kommission zur Reinhaltung des Rheins on isoproturone and chlorotolurone concentrations in Rhine water, which used to be quite high in the Lower Rhine in the past. Further, an incident involving chloracetophenone release into the Rhine was followed up, and the effects on freshwater supply were assessed. The report also contains two practical contributions by member waterworks on de-acidification of shore filtrate and on the calcite solubility of the raw water of a shore filtration and production plant. There is also a chapter on further options for evaluating long-term measuring series using time series analysis and enhanced statistical methods. [German] Die Arbeitsgemeinschaft Rhein-Wasserwerke e. V. (ARW) legt hiermit bereits ihren 59. Jahresbericht vor, in dem ueber ihre Taetigkeiten, wesentliche Ergebnisse aus dem Untersuchungsprogramm der Rheinwasserwerke und aktuelle Entwicklungen aus der Wasserwirtschaft berichtet wird. Neben der Dokumentation und Bewertung der aktuellen Daten aus dem Untersuchungsprogramm, an dem zahlreiche Wasserwerke aktiv beteiligt sind, wird in dem vorliegenden Jahresbericht ueber ein gemeinsames Sondermessprogramm der ARW und der Deutschen Kommission zur Reinhaltung des Rheins zum Vorkommen und zur Bilanzierung der Eintraege von Isoproturon und Chlortoluron berichtet, die in der Vergangenheit in z. T. sehr hohen Konzentrationen im Niederrhein gefunden wurden. Ebenfalls durch zusaetzliche Untersuchungen der Wasserwerke konnte ein Schadensfall mit Chloracetophenon am Rhein verfolgt und die Auswirkungen auf die Trinkwassergewinnung abgeschaetzt werden. Des Weiteren sind zwei praxisnahe Beitraege aus Mitgliedswerken zur Entsaeuerung von Uferfiltrat und zum

  17. Dynamic effects in the decay of the 59Cu compound nucleus

    International Nuclear Information System (INIS)

    Fornal, B.; Natositz, J.B.; Nebbia, G.; Prete, G.; Viesti, G.

    1990-01-01

    In the last few years a number of light particle emission measurements were performed to study angular momentum effects in the decay of light mass compound nuclei at excitation energies ∼100 MeV formed in heavy ion induced complete fusion reactions. A general observation in these kind of experiments is that for spin ranges where the rotating liquid drop model (RLDM) predicts near spherical shapes the deexcitation of 59 Cu compound nucleus is well described by the standard statistical model calculations. However, as the angular momentum increases to values for which the RLDM predicts significant deformations, important differences between the experimental and calculated spectra are observed. The statistical calculations using standard parameters: RLDM yrast line, Lang level density formula and transmission coefficients from the optical model, lead to the more high energy α-particles then experimentally observed. The situation is illustrated in this paper where the experimental and calculated spectra are compared for α-emission from 59 Cu nuclei produced in the reaction of 150 MeV 32 S with 27 Al. The experiments were performed at the Tandem XTU in Laboratori Nazionali di Legnaro. A subtraction technique was used to isolate spectra corresponding to compound nucleus angular moments 27 ℎ max /F min = 1.2 at J = 27ℎ to R max /R min = 2.0 at J = 39ℎ. It was recognized that the fitting of the α-spectra required a level density enhancement estimated to be ∼ 100 times then that calculated using the Lang formula in the case of 59 Cu at J = 34 ℎ and E x = 60 MeV

  18. Association Between Promoter Polymorphisms in CD46 and CD59 in Kidney Donors and Transplant Outcome

    Directory of Open Access Journals (Sweden)

    Laura A. Michielsen

    2018-05-01

    Full Text Available Complement regulating proteins, including CD46, CD55, and CD59, protect cells against self-damage. Because of their expression on the donor endothelium, they are hypothesized to be involved in accommodation. Polymorphisms in their promoter regions may affect their expression. The aim of this study was to investigate if donor polymorphisms in complement regulating proteins influence kidney transplant outcomes. We included 306 kidney transplantations between 2005 and 2010. Five polymorphisms in the promoters of CD46, CD55, and CD59 were genotyped. A CD59 promoter polymorphism (rs147788946 in donors was associated with a lower 1-year rejection-free survival [adjusted hazard ratio (aHR 2.18, 95% CI 1.12–4.24] and a trend toward impaired 5-year graft survival (p = 0.08. Patients receiving a kidney with at least one G allele for the CD46 promoter polymorphism rs2796267 (A/G showed a lower rejection-free survival, though this became borderline significant after adjustment for potential confounders (aHR 1.87, 95% CI 0.96–3.65. A second CD46 promoter polymorphism (rs2796268, A/G, was also associated with a lower freedom from acute rejection in the presence of at least one G allele (aHR 1.95, 95% CI 1.03–3.68. Finally, the combined presence of both favorable genotypes of rs2796267 and rs147788946 had an additional protective effect both on acute rejection (p = 0.006 and graft survival (p = 0.03. These findings could help to identify patients who could benefit from intensified immunosuppressive therapy or novel complement inhibitory therapeutics.

  19. Social Costs of Iron Deficiency Anemia in 6–59-Month-Old Children in India

    Science.gov (United States)

    Plessow, Rafael; Arora, Narendra Kumar; Brunner, Beatrice; Tzogiou, Christina; Eichler, Klaus; Brügger, Urs; Wieser, Simon

    2015-01-01

    Introduction Inadequate nutrition has a severe impact on health in India. According to the WHO, iron deficiency is the single most important nutritional risk factor in India, accounting for more than 3% of all disability-adjusted life years (DALYs) lost. We estimate the social costs of iron deficiency anemia (IDA) in 6–59-month-old children in India in terms of intangible costs and production losses. Materials and Methods We build a health economic model estimating the life-time costs of a birth cohort suffering from IDA between the ages of 6 and 59 months. The model is stratified by 2 age groups (6–23 and 24–59-months), 2 geographical areas (urban and rural), 10 socio-economic strata and 3 degrees of severity of IDA (mild, moderate and severe). Prevalence of anemia is calculated with the last available National Family Health Survey. Information on the health consequences of IDA is extracted from the literature. Results IDA prevalence is 49.5% in 6–23-month-old and 39.9% in 24–58-month-old children. Children living in poor households in rural areas are particularly affected but prevalence is high even in wealthy urban households. The estimated yearly costs of IDA in 6–59-month-old children amount to intangible costs of 8.3 m DALYs and production losses of 24,001 m USD, equal to 1.3% of gross domestic product. Previous calculations have considerably underestimated the intangible costs of IDA as the improved WHO methodology leads to a threefold increase of DALYs due to IDA. Conclusion Despite years of iron supplementation programs and substantial economic growth, IDA remains a crucial public health issue in India and an obstacle to the economic advancement of the poor. Young children are especially vulnerable due to the irreversible effects of IDA on cognitive development. Our research may contribute to the design of new effective interventions aiming to reduce IDA in early childhood. PMID:26313356

  20. Safety and immunogenicity of a recombinant parvovirus B19 vaccine formulated with MF59C.1.

    Science.gov (United States)

    Ballou, W Ripley; Reed, Jennifer L; Noble, William; Young, Neal S; Koenig, Scott

    2003-02-15

    A recombinant human parvovirus B19 vaccine (MEDI-491; MedImmune) composed of the VP1 and VP2 capsid proteins and formulated with MF59C.1 adjuvant was evaluated in a randomized, double-blind, phase 1 trial. Parvovirus B19-seronegative adults (n=24) received either 2.5 or 25 microg MEDI-491 at 0, 1, and 6 months. MEDI-491 was safe and immunogenic. All volunteers developed neutralizing antibody titers that peaked after the third immunization and were sustained through study day 364.

  1. Social Costs of Iron Deficiency Anemia in 6-59-Month-Old Children in India.

    Directory of Open Access Journals (Sweden)

    Rafael Plessow

    Full Text Available Inadequate nutrition has a severe impact on health in India. According to the WHO, iron deficiency is the single most important nutritional risk factor in India, accounting for more than 3% of all disability-adjusted life years (DALYs lost. We estimate the social costs of iron deficiency anemia (IDA in 6-59-month-old children in India in terms of intangible costs and production losses.We build a health economic model estimating the life-time costs of a birth cohort suffering from IDA between the ages of 6 and 59 months. The model is stratified by 2 age groups (6-23 and 24-59-months, 2 geographical areas (urban and rural, 10 socio-economic strata and 3 degrees of severity of IDA (mild, moderate and severe. Prevalence of anemia is calculated with the last available National Family Health Survey. Information on the health consequences of IDA is extracted from the literature.IDA prevalence is 49.5% in 6-23-month-old and 39.9% in 24-58-month-old children. Children living in poor households in rural areas are particularly affected but prevalence is high even in wealthy urban households. The estimated yearly costs of IDA in 6-59-month-old children amount to intangible costs of 8.3 m DALYs and production losses of 24,001 m USD, equal to 1.3% of gross domestic product. Previous calculations have considerably underestimated the intangible costs of IDA as the improved WHO methodology leads to a threefold increase of DALYs due to IDA.Despite years of iron supplementation programs and substantial economic growth, IDA remains a crucial public health issue in India and an obstacle to the economic advancement of the poor. Young children are especially vulnerable due to the irreversible effects of IDA on cognitive development. Our research may contribute to the design of new effective interventions aiming to reduce IDA in early childhood.

  2. The Co59 nuclear magnetic resonances in (Ysub(1-x)Gdsub(x))2Co17

    International Nuclear Information System (INIS)

    Nagai, Hiroyuki; Yoshie, Hiroshi; Unate, Takao; Tsujimura, Akira; Deportes, J.

    1976-01-01

    The nuclear magnetic resonances of Co 59 in (Ysub(1-x)Gdsub(x)) 2 Co 17 have been observed at 77 K as a function of x (0 2 Co 17 and Gd 2 Co 17 is at most 7 kOe in magnitude, which is comparable to that obtained in GdCo 5 . The sign of the obtained difference depends on the Co sites. The difference is qualitatively explained as the contribution of 4f electrons of Gd atoms to the hyperfine field. The temperature dependence of the resonance frequencies in Gd 2 Co 17 has also been measured. (auth.)

  3. A monocrystal of 59Co as a nuclear orientation thermometer in neutron experiments with oriented targets

    International Nuclear Information System (INIS)

    Fasoli, U.; Galeazzi, G.; Pavan, P.; Toniolo, D.; Zago, G.; Zannoni, R.

    1980-01-01

    An apparatus for measuring temperatures in the millikelvin region is described based on the 'deformation effect' on fast neutron transmission through an aligned 59 Co monocrystal, employing a 252 Cf pill as the neutron source. A statistical accuracy of a few percent in a few minutes is obtainable with a heat input of some tens of pW. The apparatus is suitable in neutron experiments with oriented targets when the gamma-ray background hinders the use of gamma-ray anisotropy thermometers. In these and similar cases, in which the temperature must be held constant for long periods, the large heat capacity of the cobalt sample is not a drawback. (orig.)

  4. Restricted replication of coronavirus MHV-A59 in primary mouse brain astrocytes correlates with reduced pathogenicity

    NARCIS (Netherlands)

    Horzinek, M.C.; Berlo, M.F. van; Wolswijk, G.; Calafat, G.; Zeijst, B.A.M. van der

    1986-01-01

    Temperature-sensitive (ts) mutants of mouse hepatitis virus A59 (MHV-A59) are drastically attenuated in their pathogenic properties. Intracerebral inoculation of mice with 10(5) PFU of mutant ts342 results in prolonged infection of the central nervous system, whereas 100 PFU of wild-type virus are

  5. 42 CFR 59.7 - What criteria will the Department of Health and Human Services use to decide which family...

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false What criteria will the Department of Health and Human Services use to decide which family planning services projects to fund and in what amount? 59.7... FOR FAMILY PLANNING SERVICES Project Grants for Family Planning Services § 59.7 What criteria will the...

  6. 40 CFR 59.626 - What emission testing must I perform for my application for a certificate of conformity?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false What emission testing must I perform for my application for a certificate of conformity? 59.626 Section 59.626 Protection of Environment... application for a certificate of conformity? This section describes the emission testing you must perform to...

  7. The $^{59}$Cu(p,$\\alpha$) cross section and its implications for nucleosynthesis in core collapse supernovae

    CERN Multimedia

    The $^{59}$Cu(p,$\\alpha$) reaction is key for heavy element synthesis in the vp-process, since it may hinder the reaction flow to higher masses by recycling material back to $^{56}$Ni and it has a strong influence on the production of the cosmic X-ray sources $^{55}$Fe and $^{59}$Ni. The intense and highly energetic $^{59}$Cu beams provided by the new HIE-ISOLDE facility will for the first time allow a direct measurement of this reaction at astrophysical energies, making it one of only few cases where a direct study is possible with a radioactive beam. We propose to measure the $^{59}$Cu(p,$\\alpha$) reaction for the first time using $^{59}$Cu beams from the HIE-ISOLDE facility.

  8. Investigation of incomplete fusion dynamics by measurement of excitation functions in the 20Ne + 59Co system

    International Nuclear Information System (INIS)

    Singh, D.; Linda, Sneha Bharti; Giri, Pankaj K.; Singh, Smita Shree; Kumar, Harish; Afzal Ansari, M.; Ali, Rahbar; Rashid, M.H.; Guin, R.; Das, S.K.

    2015-01-01

    In the present work, an attempt has been made to address some important aspects of CF and ICF dynamics for the system 20 Ne + 59 Co in the projectile energy range ≈ 62–150 MeV by using recoil catcher activation technique with the following off-line γ-ray spectroscopy. Excitation Functions (EFs) for the following reactions: 59 Co(Ne, α p4n) 70 Ga, 59 Co(Ne, 3αp3n) 63 Zn, 59 Co (Ne, 3αp4n) 62 Zn and 59 Co (Ne, 4α3n) 60 Cu have been measured. No precursor decay contribution has been observed for these measured evaporation residues. The measured values of total fusion cross-sections of the above evaporation residues have been compared with the theoretical total complete fusion cross sections calculated by code PACE-2, which do not take into account ICF contribution

  9. Effect of some factors on foliar absorption and mobility of Fe59 in plant

    International Nuclear Information System (INIS)

    Mohamed, F.A.

    1990-01-01

    Three experiments were conducted under greenhouse conditions using Fe 59 and seedlings of guava and orange to study the effect of PH value (3-8), Fe SO 4 concentrations in combination with three values of PH on foliar absorption and mobility of Fe. In addition, a comparative study to evaluate some compounds of iron for foliar spray was achieved. Foliar absorption of Fe 59 by guava leaves and its mobility were considerably influenced by PH value of spray solution. Maximum absorption and translocation were observed at PH 6. However, most of the absorbed iron 'about 90%' was retained in the treated leaves and the portion 'about 10%' acropetally and basipetally translocated. Upward transport of iron was more pronounced than downward one. Total iron in plant derived from applied FeSO 4 was greatly increased, whereas utilization percent of it was reduced by increasing the rate of Fe in spray solution. Generally, FeSO 4 had a good efficiency which ranged from about 25-43%. Specific absorption of iron by orange leaves was higher than that of guava leaves. From plant nutritional point of view, efficiency of FeSo 4 , Fe-metalosate and multi mineral-metalosate as different sources of Fe through foliar application remarkably varied and FeSO 4 was highly efficient one in comparison with metalosate compounds

  10. Backscattering of 59.54 keV photons for characterization of metallic elements

    International Nuclear Information System (INIS)

    Elyaseery, I.S.; Chong Chon Sing; Ahmad Shukri Mustapa Kamal; Abdul Aziz Tajuddin

    2000-01-01

    Scattering measurements of x-rays and gamma rays have been developed for the characterization of internal features of materials such as density or composition. Previous studies were generally carried at small scattering angles. In this paper, a system is described for preliminary studies of back scattering of photons for characterization of materials. The apparatus consist of an annular 100 mCi 241 Am source and a high purity thin intensities for the 59.54 keV photons are presented for different metallic elements such as Al, Cu, Zn, Zr, Nb, Mo, Ag, Cd, In, Sn, Ta and W. The measurements were carried out at back scattering angles of 145 0 , 154 0 , 165 0 . Coherent peak measurements offer greater sensitivity than Compton peak measurements. In particular, the 59.54 keV coherent peak intensity shows a proportional increase with increasing Z number elements except for the elements Ta and W whose absorption edges are in the vicinity of this photon energy. The experimental results demonstrate the feasibility of the backscattering method for the characterization of metallic elements. (Author)

  11. Deformation effect in the fast neutron total cross section of aligned /sup 59/Co

    Energy Technology Data Exchange (ETDEWEB)

    Fasoli, U.; Pavan, P.; Toniolo, D.; Zago, G.; Zannoni, R.; Galeazzi, G.

    1982-07-19

    The variation of the total neutron cross section, ..delta.. sigma/sub align/, on /sup 59/Co due to nuclear alignment of the target in the beam direction, has been measured over the energy range from 0.8 to 20 MeV, employing a cobalt single-crystal with a 34% nuclear alignment degree. The results show that ..delta.. sigma/sub align/ oscillates from a minimum of -5% at about 2.5 MeV to a maximum of +1% at about 10 MeV. The data were successfully fitted by optical model coupled-channel calculations. The coupling terms were deduced from a model representing the /sup 59/Co nucleus as a virbrational /sup 60/Ni core coupled to a proton-hole in a (lf 7/2) shell, without free parameters. The optical model parameters were determined by fitting the total cross-section independently measured. The theoretical calculations show that, at lower energies, ..delta.. sigma/sub align/ depends appreciably on the coupling with the low-lying levels.

  12. Deformation effect in the fast neutron total cross section of alligned 59Co

    International Nuclear Information System (INIS)

    Fasoli, U.; Pavan, P.; Toniolo, D.; Zago, G.; Zannoni, R.; Galeazzi, G.

    1982-01-01

    The variation of the total neutron cross section, DELTAsigmasub(align), on 59 Co due to nuclear alignement of the target in the beam direction, has been measured over the energy range from 0.8 to 20 MeV, emploing a cobalt single-crystal with a 34% nuclear alignment degree. The results show that DELTAsigmasub(align) oscillates from a minimum of -5% at about 2.5 MeV to a maximum of +1% at about 10 MeV. The data were succesfully fitted by optical model coupled-channel calculations. The coupling terms were deduced from a model representing the 59 Co nucleus as a vibrational 60 Ni core coupled to a proton hole in a (lf7/2) shell, without free parameters. The optical model parameters were determined by fitting the total cross section independently measured. The theoretical calculations show that, at lower energies, DELTAsigmasub(align) depends appreciably on the coupling with the low-liyng levels

  13. Deformation effect in the fast neutron total cross section of aligned 59Co

    International Nuclear Information System (INIS)

    Fasoli, U.; Pavan, P.; Toniolo, D.; Zago, G.; Zannoni, R.; Galeazzi, G.

    1983-01-01

    The variation of the total neutron cross section, Δsigma/sub align/, on 59 Co due to nuclear alignment of the target has been measured over the energy range from 0.8 to 20 MeV employing a cobalt single crystal with a 34% nuclear alignment. The results show that Δsigma/sub align/ oscillates from a minimum of -5% at about 2.5 MeV to a maximum of +1% at about 10 MeV. The data were successfully fitted by optical model coupled-channel calculations. The coupling terms were deduced from a model representing the 59 Co nucleus as a vibrational 60 Ni core coupled to a proton hole in a (1f/sub 7/2/) shell, without free parameters. The optical model parameters were determined by fitting the total cross section, which was independently measured. The theoretical calculations show that, at lower energies, Δsigma/sub align/ depends appreciably on the coupling with the low-lying levels

  14. Separation for the determination of 59/63Ni in radioactive wastes

    International Nuclear Information System (INIS)

    Lee, Chang Heon; Choi, Kwang Soon; Jee, Kwang Young; Kim, Won Ho; Jung, Kie Chul

    2005-01-01

    A study on the separation of 99 Tc, 94 Nb, 55 Fe, 90 Sr and 59/63 Ni in various radioactive wastes discharged from nuclear power plants has been performed for a use in their quantification which is indispensable for the evaluation of the radionuclide inventory. Ni was recovered along with Ca, Mg, Al, Cr, Ti, Mn, Ce, Na, K. and Cu through the sequential separation procedure of Re (as a surrogate of 99 Tc), Nb, Fe and Sr by anion exchange and Sr-SPec extraction chromatography. In this research, chemical separation of Ni from the co-existing elements was investigated by cation exchange and Ni-Spec extraction chromatography. Precipitation behaviour of Ni and the co-existing elements with dimethylglyoxime(DMG) was investigated in ammonium citrate/ethanol-H 2 O and tartaric acid/acetone-H 2 O in order to purify separated Ni fractions and to prepare 59/63 Ni source for the radioactivity measurement using a gas proportional counter. Recovery of Ni separated through ion exchange chromatographic separation procedure was 93.1% with relative standard deviation of 0.9%. In addition, recovery of Ni with DMG in the tartaric acid/acetone-H 2 O was 85.6% with relative standard deviation of 1.9%

  15. Moderate Acute Malnutrition Treatment among Children 6-23 Months and 24-59 Months Aged

    International Nuclear Information System (INIS)

    Mahamadou, Tanimoune; Traore, Modibo; Fainke, Kamayera; Magagi, Saidou

    2014-01-01

    Full text: The prevalence of acute malnutrition in Mali has slightly decreased between 2012 and 2013 in southern areas from 8.9 to 8.6 percent.The youngest children 6-23 months are seriously affected as 12.6% according the SMART nutrition survey in 2013. The aim of this study was to show how seasonality impacts relapse rates among youngest moderately malnourished children aged 6-23 month compare to 24-59 months. The World Food Programme in Mali set up Targeted Supplementary Feeding Programme (TSFP) in 1032 community health facilities to address the burden of MAM. This TSFP includes treatment of MAM with 92g of Plumpy’SupTM per days during 60 days. The entry criteria according to national protocol was Mid Upper Arm Circumference less than 125mm (MUAC = 125 mm or WHZ > = -1.5 during two consecutives visits. In addition, the programme is accompanied with community based activities such as active screening and culinary demonstration for women groups and sensitization. As a result, after 10 months of implementation, 41604 children 6-23 months aged have been admitted for MAM treatment. This represents 82% of total estimated caseload in this group (50666). During the same period, only 14% (14473) of total estimated caseload (101333) in children 24-59 months aged group have been admitted and treated. Although 74% (41604) of total admission (56077 children 6-59 months) was 6-23 months aged ,the programme performance indicators show that children 24-59 respond better to the treatment compared to 6-23 months: Average recovery rate 88% vs 87%; death rate 0.55% vs 1.07% none response 0.21% vs 0.50%. Only, the defaulter rate was higher in 24-59, 10.21% vs 7.5%. Nevertheless, compared two Sphere performance norms and threshold, the programme is fully satisfactory in all categories. The seasonal analysis shows that the highest admission in MAM programme was registered between April and September in all categories. 79% of the total caseload has been admitted during this period

  16. Prognostic value of semiquantification NP-59 SPECT/CT in primary aldosteronism patients after adrenalectomy

    International Nuclear Information System (INIS)

    Lu, Ching-Chu; Cheng, Mei-Fang; Tzen, Kai-Yuan; Yen, Ruoh-Fang; Wu, Vin-Cent; Wu, Kwan-Dun; Liu, Kao-Lang; Lin, Wei-Chou

    2014-01-01

    Primary aldosteronism (PA), characterized by an excessive production of aldosterone, affects 5-13 % of patients with hypertension. Accurate strategies are needed for the timely diagnosis of PA to allow curability and prevention of excessive cardiovascular events and related damage. This study aimed to evaluate the usefulness of semiquantification of 131 I-6β-iodomethyl-norcholesterol (NP-59) single photon emission computed tomography (SPECT)/CT in differentiating aldosterone-producing adenoma (APA) from idiopathic adrenal hyperplasia (IAH) and in predicting clinical outcomes after adrenalectomy. We retrospectively reviewed 49 PA patients who had undergone adrenalectomy after NP-59 SPECT/CT within 1 year. A conventional visual scale (VS) and two semiquantitative parameters generated from SPECT/CT, adrenal to liver ratio (ALR) and lesion to contralateral ratio of bilateral adrenal glands (CON), with cutoff values calculated by receiver-operating characteristic (ROC) analysis, were compared with pathology results and postsurgical outcomes to determine the accuracy. An ALR cutoff of 1.84 and a CON cutoff of 1.15 showed an ability to distinguish adenoma from hyperplasia similar to VS (p = 0.2592 and 0.1908, respectively). An ALR cutoff of 2.28 and a CON cutoff of 1.11 yielded the highest sensitivity and specificity to predict postsurgical outcomes, and an ALR of 2.28 had an ability superior to VS (p = 0.0215), while a CON of 1.11 did not (p = 0.1015). Patients with either ALR or CON greater than the cutoff had a high probability of positive postsurgical outcomes (n = 36/38), while patients with both ALR and CON less than the cutoff had a low probability of positive postsurgical outcomes (n = 2/11). Semiquantification of NP-59 scintigraphy has an ability similar to VS in differentiating APA from IAH, but an excellent ability to predict postsurgical outcomes of adrenalectomy. An ALR or CON greater than the cutoff strongly suggests benefits from adrenalectomy, and both

  17. Prognostic value of semiquantification NP-59 SPECT/CT in primary aldosteronism patients after adrenalectomy

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Ching-Chu; Cheng, Mei-Fang; Tzen, Kai-Yuan; Yen, Ruoh-Fang [National Taiwan University Hospital and National Taiwan University College of Medicine, Department of Nuclear Medicine, Taipei (China); Wu, Vin-Cent; Wu, Kwan-Dun [National Taiwan University Hospital and National Taiwan University College of Medicine, Department of Internal Medicine, Taipei (China); Liu, Kao-Lang [National Taiwan University Hospital and National Taiwan University College of Medicine, Department of Medical Imaging, Taipei (China); Lin, Wei-Chou [National Taiwan University Hospital and National Taiwan University College of Medicine, Department of Pathology, Taipei (China); Collaboration: the TAIPAI Study Group

    2014-07-15

    Primary aldosteronism (PA), characterized by an excessive production of aldosterone, affects 5-13 % of patients with hypertension. Accurate strategies are needed for the timely diagnosis of PA to allow curability and prevention of excessive cardiovascular events and related damage. This study aimed to evaluate the usefulness of semiquantification of {sup 131}I-6β-iodomethyl-norcholesterol (NP-59) single photon emission computed tomography (SPECT)/CT in differentiating aldosterone-producing adenoma (APA) from idiopathic adrenal hyperplasia (IAH) and in predicting clinical outcomes after adrenalectomy. We retrospectively reviewed 49 PA patients who had undergone adrenalectomy after NP-59 SPECT/CT within 1 year. A conventional visual scale (VS) and two semiquantitative parameters generated from SPECT/CT, adrenal to liver ratio (ALR) and lesion to contralateral ratio of bilateral adrenal glands (CON), with cutoff values calculated by receiver-operating characteristic (ROC) analysis, were compared with pathology results and postsurgical outcomes to determine the accuracy. An ALR cutoff of 1.84 and a CON cutoff of 1.15 showed an ability to distinguish adenoma from hyperplasia similar to VS (p = 0.2592 and 0.1908, respectively). An ALR cutoff of 2.28 and a CON cutoff of 1.11 yielded the highest sensitivity and specificity to predict postsurgical outcomes, and an ALR of 2.28 had an ability superior to VS (p = 0.0215), while a CON of 1.11 did not (p = 0.1015). Patients with either ALR or CON greater than the cutoff had a high probability of positive postsurgical outcomes (n = 36/38), while patients with both ALR and CON less than the cutoff had a low probability of positive postsurgical outcomes (n = 2/11). Semiquantification of NP-59 scintigraphy has an ability similar to VS in differentiating APA from IAH, but an excellent ability to predict postsurgical outcomes of adrenalectomy. An ALR or CON greater than the cutoff strongly suggests benefits from adrenalectomy, and

  18. BEBERAPA FAKTOR RISIKO GIZI KURANG DAN GIZI BURUK PADA BALITA 12 - 59 BULAN

    Directory of Open Access Journals (Sweden)

    Dedi Alamsyah

    2015-09-01

    Full Text Available Abstract: Several Risk Factors Of Moderate And Severe Malnutrition In Children Under Five Years Old Aged 12-59 Months. The type of research was observational using case-control study and the qualitative study through the in-depth interview (mixed method. The research location was in Pontianak City. The number of samples was 80 people consisting of 40 people from a case and 40 people from control. Assessment of nutritional using anthropometry measurement based on weight for height. Height measurement using microtome and measure weighting scale. Result show that the multivariate analysis found two variables significantly associated with the prevalence of moderate and severe malnutrition in children under five years old aged 12-59 months, i.e.: poor of attitude toward food (OR = 6.980, p = 0.002, 95% CI = 1.998-24.385 and poor environmental health (OR = 5.033, p = 0.012, 95% CI = 1.432-17.683. Keywords: risk factors, moderate and severe malnutrition, children, pontianak Abstrak : Beberapa Faktor Risiko Gizi Kurang Dan Gizi Buruk Pada Balita 12-59 Bulan. Tujuan penelitian yaitu untuk membuktikan faktor risiko agent, host dan environment yang berpengaruh terhadap kejadian gizi kurang dan gizi buruk pada balita di kota Pontianak. Penelitian ini bersifat observasional dengan pendekatan case control. Lokasi penelitian dilaksanakan di Kota Pontianak. Jumlah sampel sebanyak 80 orang, yang terdiri dari kasus sebanyak 40 orang dan kontrol sebanyak 40 orang. Penilaian status gizi menggunakan pengukuran antropometri berdasarkan berat badan per tinggi badan (BB/TB. Pengukuran tinggi badan menggunakan microtoise dan mengukur berat badan menggunakan timbangan balita. Berdasarkan hasil analisa multivariat menunjukkan terdapat hubungan yang signifikan yaitu sikap ibu terhadap makanan buruk (OR : 6,98 p = 0,002 95 % CI 1,99-24,38 dan kesehatan lingkungan buruk (OR : 5,03 p = 0,012 95 % CI 1,43-17,68 dengan kejadian gizi kurang dan gizi buruk pada anak balita. Kata

  19. Progression from productive infection to integration and oncogenic transformation in human papillomavirus type 59-immortalized foreskin keratinocytes.

    Science.gov (United States)

    Spartz, Helena; Lehr, Elizabeth; Zhang, Benyue; Roman, Ann; Brown, Darron R

    2005-05-25

    Studies of changes in the virus and host cell upon progression from human papillomavirus (HPV) episomal infection to integration are critical to understanding HPV-related malignant transformation. However, there exist only a few in vitro models of both productive HPV infection and neoplastic progression on the same host background. We recently described a unique foreskin keratinocyte cell line (ERIN 59) that contains HPV 59 (a close relative of HPV 18). Early passages of ERIN 59 cells (passages 9-13) contained approximately 50 copies of episomes/cell, were feeder cell-dependent, and could be induced to differentiate and produce infectious virus in a simple culture system. We now report that late passage cells (passages greater than 50) were morphologically different from early passage cells, were feeder cell independent, and did not differentiate or produce virus. These late passage cells contained HPV in an integrated form. An integration-derived oncogene transcript was expressed in late passage cells. The E2 open reading frame was interrupted in this transcript at nucleotide 3351. Despite a lower viral genome copy number in late passage ERIN 59 cells, expression of E6/E7 oncogene transcripts was similar to early passage cells. We conclude that ERIN 59 cells are a valuable cell line representing a model of progression from HPV 59 episomal infection and virus production to HPV 59 integration and associated oncogenic transformation on the same host background.

  20. Choledocholithiasis and endo-laparoscopic rendezvous. Analysis of 59 consecutive cases.

    Science.gov (United States)

    Del Rio, Paolo; Dell'Abate, Paolo; Labonia, Domenico; Negri, Marco; Sianesi, Nicoletta; Arcuri, Maria Francesca; Sianesi, Mario

    2011-01-01

    Choledocholithiasis is a real problem of major clinical importance. The incidence of cholelithiasis is 10-20%. We have examined 2907 patients treated with videolaparoscopic cholecystectomy (VLC) between January 2001 and September 2009. 214 cases (7.4%) were affected by choledocolithiasis; among these, 59 consecutive cases were treated by rendezvous, 151 cases by sequential treatment (ERCP-ES before VLC), 3 cases by extraction with Dormia's basket, and 1 case by ERCP-ES after VLC. The complications were one biliary fistula and three hemorrhages (one from the cystic artery, one from the hepatic area and one from trocar's site). The mean hospital stay was 1.38 +/- 0.83 days for the rendezvous group vs 4 53 +/- 0.74 days in the sequential treatment group (prendezvous procedure reduces hospital stay and has a greater compliance (only one treatment). We can use this option in the management of cases where preoperative ERCP-ES has failed.

  1. Observation of solar HLy-α by K-9M-59 rocket

    International Nuclear Information System (INIS)

    Watanabe, Norihiko; Tono, Ichiro; Koshio, Takafumi.

    1978-01-01

    The purpose of the observation is to measure the illumination intensity of solar HLy-α (1216 A) and the altitude distribution of O 2 density in earth atmosphere. Since solar HLy-α is strongly absorbed by O 2 in the earth atmosphere, the extinction of HLy-α depends on the altitude distribution of O 2 density. The K-9M-59 rocket was launched on September 3, 1977. The HLy-α detector was a narrow-band ion chamber filled with NO gas. The result showed that the solar HLy-α irradiance at the rocket altitude of 90 km was 3.5 x 10 11 photons/cm 2 s and the altitude distribution of O 2 density was obtained. (Yoshimori, M.)

  2. Interactions between 59Fe(14C)EDTA and soils containing calcium carbonate

    International Nuclear Information System (INIS)

    Hargitai-Toth, A.; Konya, J.

    1991-01-01

    Interaction between FeEDTA and calcareous soils was followed over a period of four weeks using a radiotracer technique, and a kinetic evaluation of the results was performed. 59 Fe served to determine the quantity of iron, 14 C to assay for EDTA and 45 Ca to measure calcium. During the experiment, i.e. within four weeks in case of the chernozem soil 61% and in case of the clayey meadow soil 51% of the iron chelate disappeared from the solution. The loss in soluble iron was partly due to a rapid sorption process of about an hour and partly due to the slow decomposition of FeEDTA to Fe(OH) 3 . The two processes could be separated using the Christiansen equation. (author) 9 refs.; 1 figs.; 2 tabs

  3. ASUPAN SENG YANG RENDAH SEBAGAI FAKTOR RISIKO KEPARAHAN PNEUMONIA PADA ANAK USIA 12-59 BULAN

    Directory of Open Access Journals (Sweden)

    Meiry Nasution

    2017-06-01

    Full Text Available Period prevalence of infant pneumonia in Indonesia is 18.5 per mile. The high mortality rate due to pneumonia of 62 percent was found in 10 countries and 5 countries was located in Asia. Zinc is one of micronutrients which is reported to prevent pneumonia as   an acute phase response to infection and help to boost the body immune response. The objective of the study was to determine the impact of zinc intake as risk factor of severe pneumonia in children. A case control study was conducted among children aged 12–59  months in 2 hospitals and 6 health centres, Yogyakarta city. Thirty four children were categorized as having severe pneumonia (cases and 102 children were categorized as having pneumonia (control.  All sample’s mothers completed a semi-quantitative food frequency questionnaire during March-April 2014. Data analysis was performed  using Mantel-Haenszel test and conditional logistic regression, α = 0,05. Results of the study showed that there were 41.2 percent cases and 56.9 percent control were exclusively breast-fed. The  proportion of cases who had inadequate zink intake was higher than control group. There was no difference between inadequate zinc intake and the severe pneumonia (OR 1,08 and  95% CI 0,5-2,3. There was a statistically significant correlation between low-zinc intake and severe pneumonia if second  disease exist (OR 3,8  and 95% CI 1,4 -10,8. As an conclusion, Inadequate zinc intake affected severe pneumonia when the secondary diseases exist in children with pneumonia.   ABSTRAK   Period prevalence pneumonia balita di Indonesia adalah 18,5 per mil. Angka kematian yang tinggi akibat pneumonia sebesar 62 persen terdapat di 10 negara dan 5 negara di antaranya merupakan negara di Asia. Defisiensi seng menyebabkan penurunan kekebalan sel sehingga meningkatkan kerentanan terhadap penyakit pneumonia. Tujuan penelitian ini menganalisis asupan seng yang kurang sebagai faktor risiko keparahan pneumonia pada anak

  4. Movement of 59Fe in Egyptian soils as affected by chelated agents

    International Nuclear Information System (INIS)

    Massoud, M.A.; Omar, M.A.; Abd-El-Sapour, M.F.

    1983-01-01

    An investigation was undertaken to study the mobility of Fe from different Fe carries; i.e. Fe 2 (So 4 ) 3 , Fe-EDDHA and Fe-DTPA, the results revealed that almost the total mobilization of Fe 2 (So 4 ) 3 beyond the top layer (1-2 cm) ranged from 35.3, 10.4 and 1.9% of added 59Fe to three investigated soils, i.e. Anshas, Sakha and Burg El-Arab. The corresponding values for Fe-EDDHA ranged from 29.9, 20.4 and 14.9%, while for Fe-DTPA it ranged from 46.9, 16.5 and 11.1 when Fe was added as EDDHA and DTPA. It was noticed that the immobilization of Fe was higher in the calcareous than in the alluvial and sandy soils

  5. Movement of /sup 59/Fe in Egyptian soils as affected by chelated agents

    Energy Technology Data Exchange (ETDEWEB)

    Massoud, M.A.; Omar, M.A.; Abd-El-Sapour, M.F. (Agriculture Department for Soil and Water, Nuclear Research Centre, A.E.A., Cairo (Egypt))

    1983-01-01

    An investigation was undertaken to study the mobility of Fe from different Fe carries; i.e. Fe/sub 2/(So/sub 4/)/sub 3/, Fe-EDDHA and Fe-DTPA, the results revealed that almost the total mobilization of Fe/sub 2/(So/sub 4/)/sub 3/ beyond the top layer (1-2 cm) ranged from 35.3, 10.4 and 1.9% of added 59Fe to three investigated soils, i.e. Anshas, Sakha and Burg El-Arab. The corresponding values for Fe-EDDHA ranged from 29.9, 20.4 and 14.9%, while for Fe-DTPA it ranged from 46.9, 16.5 and 11.1 when Fe was added as EDDHA and DTPA. It was noticed that the immobilization of Fe was higher in the calcareous than in the alluvial and sandy soils.

  6. [Prostate cancer patients with lymph node metastasis. Outcome in a consecutive group of 59 patients

    DEFF Research Database (Denmark)

    Roder, M.A.; Reinhardt, S.; Brasso, K.

    2008-01-01

    INTRODUCTION: The optimal management of prostate cancer patients with lymph node metastasis remains controversial. In this article, the outcome in a consecutive group of patients with newly diagnosed lymph node positive prostate cancer is presented. MATERIALS AND METHODS: In 59 patients...... with histological verified lymph node positive disease but without osseous metastasis, outcome is described by time to biochemical progression, time to metastasis and survival. RESULTS: Median age at diagnosis was 62 years. Median pre-treatment PSA was 21 ng/ml. Endocrine treatment was initiated within median 2...... patients died during follow-up, 15 deaths were attributable to prostate cancer. Estimated median survival was 5.5 years. CONCLUSION: Despite early androgen deprivation therapy, patients with lymph node positive prostate cancer have a grave prognosis with a high risk of progression and disease...

  7. The Green Bank Ammonia Survey: Unveiling the Dynamics of the Barnard 59 Star-forming Clump

    Science.gov (United States)

    Redaelli, E.; Alves, F. O.; Caselli, P.; Pineda, J. E.; Friesen, R. K.; Chacón-Tanarro, A.; Matzner, C. D.; Ginsburg, A.; Rosolowsky, E.; Keown, J.; Offner, S. S. R.; Di Francesco, J.; Kirk, H.; Myers, P. C.; Hacar, A.; Cimatti, A.; Chen, H. H.; Chen, M. C.; Lee, K. I.; Seo, Y. M.

    2017-12-01

    Understanding the early stages of star formation is a research field of ongoing development, both theoretically and observationally. In this context, molecular data have been continuously providing observational constraints on the gas dynamics at different excitation conditions and depths in the sources. We have investigated the Barnard 59 core, the only active site of star formation in the Pipe Nebula, to achieve a comprehensive view of the kinematic properties of the source. This information was derived by simultaneously fitting ammonia inversion transition lines (1, 1) and (2, 2). Our analysis unveils the imprint of protostellar feedback, such as increasing line widths, temperature, and turbulent motions in our molecular data. Combined with complementary observations of dust thermal emission, we estimate that the core is gravitationally bound following a virial analysis. If the core is not contracting, another source of internal pressure, most likely the magnetic field, is supporting it against gravitational collapse and limits its star formation efficiency.

  8. Influence of heat and radiation on the germinability and viability of B. cereus BIS-59 spores

    International Nuclear Information System (INIS)

    Kamat, A.S.; Lewis, N.F.

    1983-01-01

    Spores of Bicillus cereus BIS-59, isolated in this laboratory from shrimps, exhibited an exponential gamma radiation survival curve with a d 10 value of 400 krad as compared with a D 10 value of 30 krad for the vegetative cells. The D 10 value of DPA-depleted spores was also 400 krad indicating that DPA does not influence the radiation response of these spores. Maximum germination monitored with irradiated spores was 60 percent as compared with 80 percent in case of unirradiated spores. Radiation-induced inhibition of the germination processes was not dose dependent. Heat treatment (15 min at 80 C) to spores resulted in activation of the germination process; however, increase in heating time (30 min and 60 min) increased the germination lag period. DPA-depleted spores were less heat resistant than normal spores and exhibited biphasic exponential inactivation. (author)

  9. Postmenopausal pregnancy? Evaluation of elevated hCG in a 59-year-old woman.

    Science.gov (United States)

    Basham, Mary Margaret; Bryan, Teresa

    2017-06-05

    Slightly elevated serum human chorionic gonadotropin (hCG) can be a normal finding in postmenopausal women. We report a case of a 59-year-old woman with a history of abnormal uterine bleeding who presented with a concern for pregnancy after developing nausea and vomiting a few weeks after unprotected intercourse. Although pregnancy was extremely unlikely, hCG was obtained in order to reassure the patient since she reported that her mother conceived at the age of 60. Serum hCG was positive, prompting concern for malignancy versus pregnancy. Stable serum hCG levels, elevated follicle-stimulating hormone and negative transvaginal ultrasound ruled out both malignancy and pregnancy. Positive serum pregnancy test and hCG elevation was attributed to normal postmenopausal state. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  10. Anterior fracture displacement in Colles’ fractures after Kapandji wiring in women over 59 years

    Science.gov (United States)

    Verdonk, René

    2006-01-01

    The aim of this study was to assess the radiological results of Colles’ fractures treated with Kapandji wiring and to determine the frequency of postoperative anterior fracture displacement. The X-rays of 89 fractures in women over 59 years of age were evaluated. Five weeks after injury, palmar shift of the distal fracture fragments and/or palmar tilt of more than 20° were observed in 26 patients. In ten wrists dorsal tilt was not sufficiently corrected and measured more than 10°. Increase in ulnar variance was more than 2 mm in 37 wrists and more than 5 mm in six wrists; this was more pronounced when the palmar tilt was not corrected properly or when anterior fracture displacement was present. We conclude that Kapandji wiring may not be able to prevent anterior fracture displacement in almost one-third of Colles’ fractures in osteoporotic elderly patients. PMID:16865364

  11. Sorption properties of new composite materials suitable for radioanalytical determination of 59-Ni and 63-Ni

    International Nuclear Information System (INIS)

    Fisera, O.; Sebesta, F.

    2006-01-01

    New composite materials for separation and radioanalytical determination of radionickel ( 59, 63 Ni) were prepared and their sorption properties were examined. Chelating agents dimethylglyoxime (DMG) and diphenylglyoxime (DFG) as active components were immobilized in porous matrix of binding polymer polyacrylonitrile (PAN). Sorption properties of these materials were compared with commercial Ni Resin (Eichrom Technologies, USA). Weight distribution ratios, sorption kinetics and operating capacities were investigated during experiments performed. The highest weight distribution ratios were found for the material DFG-PAN. The sorbent DMG-PAN has the highest operating capacity. The fastest kinetics of nickel sorption was determined for the commercial Ni Resin. Elution of nickel with nitric acid solution allows subsequent and direct determination of radionickel by liquid scintillation counting. (author)

  12. Minutes of the twelfth INDC meeting, Vienna, 5-9 October 1981

    International Nuclear Information System (INIS)

    Yiftah, S.

    1982-08-01

    The Twelfth Meeting of the INDC was held at IAEA Headquarters in Vienna from 5-9 October 1981. The meeting was attended by 13 committee members (member from Australia excused), six advisers and three observers from 14 Member States and two international organisations. The committee reviewed the nuclear data activities of the IAEA, in Member States and in nuclear data centres during the period since its Eleventh Meeting in Vienna in June 1980. It also discussed and reviewed in detail the Agency's future nuclear data programme for the period 1982-84. In general, the IAEA nuclear data programme reflects the trends discussed and detailed at the 11th INDC Meeting. The official minutes include summaries of the discussions of the agenda items, full reports of subcommittees, list of actions, together with lists of participants and subcommittee membership

  13. Dissipative and transition phenomena in the 32S+59Co reaction

    International Nuclear Information System (INIS)

    Fahli, A.

    1983-02-01

    The underlying reaction mecanisms for dissipative fissionlike process in the 32 S+ 59 Co reaction have been studied between 128 and 198 MeV of incident 32 S. The mass and angular distributions and the total kinetic energies for fissionlike fragments where measured. The cross sections for the production of fusion evaporation and fissionlike fragments were determined and the fusion cross section deduced. The latter was compared to various fusion model predictions including ones developed to describe the so called fast fission and quasi-fission. The results are interpreted in terms of a process which we call dynamical fission the basic concepts of which are consistent with the extra-extra push model [fr

  14. Societal Costs of Micronutrient Deficiencies in 6- to 59-month-old Children in Pakistan.

    Science.gov (United States)

    Wieser, Simon; Brunner, Beatrice; Tzogiou, Christina; Plessow, Rafael; Zimmermann, Michael B; Farebrother, Jessica; Soofi, Sajid; Bhatti, Zaid; Ahmed, Imran; Bhutta, Zulfiqar A

    2017-12-01

    In Pakistan, nearly half of children younger than 5 years are stunted, and 1 in 3 is underweight. Micronutrient deficiencies, a less visible form of undernutrition, are also endemic. They may lead to increased morbidity and mortality as well as to impaired cognitive and physical development. To estimate the lifetime costs of micronutrient deficiencies in Pakistani children aged between 6 and 59 months. We develop a health economic model of the lifetime health and cost consequences of iodine, iron, vitamin A, and zinc deficiencies. We assess medical costs, production losses in terms of future incomes lost, and disability-adjusted life-years (DALYs). The estimation is based on large population surveys, information on the health consequences of micronutrient deficiencies extracted from randomized trials, and a variety of other sources. Total societal costs amount to US$46 million in medical costs, US$3,222 million in production losses, and 3.4 million DALYs. Costs are dominated by the impaired cognitive development induced by iron-deficiency anemia in 6- to 23-month-old children and the mortality caused by vitamin A deficiency. Costs are substantially higher in poorer households. Societal costs amounted to 1.44% of gross domestic product and 4.45% of DALYs in Pakistan in 2013. These costs hinder the country's development. They could be eliminated by improved nutrition of 6- to 59-month-old children and public health measures. Our results may contribute to the design of cost-effective interventions aiming to reduce micronutrient deficiencies in early childhood and their lifetime consequences.

  15. Kadar kalsium serum pada anak stunting dan tidak stunting usia 24-59 bulan

    Directory of Open Access Journals (Sweden)

    Yulinda Kurniasari

    2016-01-01

    Full Text Available Background: Children with stunning as the accumulations of the lack of nutrient or continuous infection are highly at risk to suffer from illness and death. In developing country, there are 165 million children under the age of suffering from stunting. Research done showed that nationally stunting prevalence in 2013 is 37,2 percent. West Borneo is one of the twenty provinces with the stunting prevalence above the national average. During the growth period, children need calcium, especially for ossification. The lack of calcium is mainly caused by inadequate intake and or non-optimal calcium absorption. Some of the previous research has shown that the level of calcium serum of children with stunting has significantly lowered than the normal children. Objective: The aim of this study was to analyze the calcium serum level of the children with stunting aged 24-59 months in Pontianak City. Method: This study is a cross-sectional design. It conducted in East Pontianak and North Pontianak subdistricts,  from July to August 2015. A number of samples were 90 children. Statistical analysis was performed using chi-square, t-test, and logistic regression. Results: There was no significance in serum calcium level between stunting and nonstunting children (p=0,193. The average of the calcium serum level of the stunting children was 12,14±1,97 mg/dl, while the nonstunting children were 12,16±1,63 mg/dl. The t-test showed that there was no significant difference (p=0,966. Conclusion: There is no significant difference of the calcium serum level between the stunting and nonstunting children aged 24- 59 months in Pontianak City (p=0,193.

  16. Asupan protein, kalsium dan fosfor pada anak stunting dan tidak stunting usia 24-59 bulan

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    Endah Mayang Sari

    2016-04-01

    Full Text Available Background: Indonesia is one of developing country which still facing a serious problem concerning stunting. Causes of stunting is a complex things, one of the cause is protein intake which is have effect on the level plasma insulin growth factor I (IGF-I, protein bone matrix and growth factor, also calcium and phosphorus that has an important role in bone formation. One of the province in Indonesia which has stunting prevalence above level of National prevalence is West Borneo. Pontianak as the capital city of West Borneo is still facing serious problem concerning stunting and the low level of food security. Objective: Analyze protein, calcium and phosphorus intake of stunting and non stunting children aged 24-49 months in Pontianak. Method: The study was an analytical observational with cross sectional design. Samples of the study were children aged 24-59 months in the districts of East Pontianak and North Pontianak, West Borneo, as much as 90 samples have been chosen by using simple random sampling technique. The research was conducted from July - August 2015. Statistical analysis was performed by using chi square and t-test. Results: Protein, calcium and phosphorus intake are lower to the stunting compare to non stunting children (p<0,05. Stunting prevalence of  lower protein group is higher 1,87 times than adequate protein intake group. Stunting prevalence of low calcium intake group is higher 3,625 times than adequate calcium intake group. Moreover, the stunting prevalence of low phosphor intake group is higher 2,29 times than adequate phosphor intake group. Conclusion: Protein, calcium and phosphor intake significant lower to the stunting compare to non stunting children aged 24- 59 months in Pontianak.

  17. Ectopic expression of the HAM59 gene causes homeotic transformations of reproductive organs in sunflower (Helianthus annuus L.).

    Science.gov (United States)

    Shulga, O A; Neskorodov, Ya B; Shchennikova, A V; Gaponenko, A K; Skryabin, K G

    2015-01-01

    The function of the HAM59 MADS-box gene in sunflower (Helianthus annuus L.) was studied to clarify homeotic C activity in the Asteraceae plant family. For the first time, transgenic sunflower plants with a modified pattern of HAM59 expression were obtained. It was shown that the HAM59 MADS-box transcription factor did mediate C activity in sunflower. In particular, it participated in termination of the floral meristem, repression of the cadastral function of A-activity, and together with other C-type sunflower protein HAM45-in the specification of the identity of stamens and pistils.

  18. Molecular and clinical characteristics of clonal complex 59 methicillin-resistant Staphylococcus aureus infections in Mainland China.

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    Juan Li

    Full Text Available Detailed molecular analyses of Clonal Complex 59 (CC59 methicillin-resistant Staphylococcus aureus (MRSA isolates from children in seven major cities across Mainland China were examined. A total of 110 CC59 isolates from invasive and non-invasive diseases were analyzed by multilocus sequence typing (MLST, Staphylococcus cassette chromosome mec (SCCmec typing, staphylococcal protein A (spa typing and pulsed-field gel electrophoresis (PFGE. Antibiotics susceptibilities, carriage of plasmids and 42 virulence genes and the expression of virulence factors were examined. ST59 (101/110, 91.8% was the predominant sequence type (ST, while single locus variants (SLVs belonging to ST338 (8/110, 7.3% and ST375 (1/110, 0.9% were obtained. Three SCCmec types were found, namely type III (2.7%, type IV (74.5% and type V (22.7%. Seven spa types including t437, which accounted for 87.3%, were determined. Thirteen PFGE types were obtained. PFGE types A and B were the major types totally accounting for 81.8%. The dominant clone was ST59-t437-IVa (65.5%, followed by ST59-t437-V (14.5%. The positive rate of luks-PV and lukF-PV PVL encoding (pvl gene was 55.5%. Plasmids were detected in 83.6% (92/110 of the strains. The plasmid size ranging from 23.4 kb to 50 kb was most prevalent which accounted for 83.7% (77/92. A significantly lower expression of hla was found in ST59-t437-IVa compared with ST59-t437-V. Among the 110 cases, 61.8% of the patients were less than 1 year old. A total of 90 cases (81.8% were community-associated (CA infections whereas 20 cases (18.2% were hospital-associated (HA infections. Out of the 110 patients, 36.4% (40/110 were diagnosed with invasive infectious diseases in which ST59-t437-IVa accounted for 67.5% (27/40. In brief, ST59-t437-IVa was proved as the dominant clone in CC59 MRSA strains. The carriage rate of pvl gene was high. CC59 MRSA could result in CA and HA infections. The majortiy of MRSA infection children were in young age.

  19. Body retention and tissue distribution of 59Fe and 54Mn in newborn rats fed iron-supplemented cow's milk

    International Nuclear Information System (INIS)

    Gruden, Nevenka

    1980-01-01

    The effect of iron-fortified cow's milk on body 59 Fe and 54 Mn retention and selective tissue distribution has been studied in newborn rats. Six-day old rats, divided into three groups were artificially fed for 7 hrs 0,45 ml of cow's milk or cow's milk enriched with either 52 or 103 μg of Fe /ml and marked with 59 Fe and 54 Mn. After 4 days there was no significant difference in whole body or carcass activity between the groups. Iron added to milk in large amounts did not influence body 59 Fe or 54 Mn retention in newborn rats, whereas it enhanced 59 Fe deposition in the liver and the intestinal wall and, to a lesser extent, 54 Mn deposition in the liver

  20. Single-cell analysis reveals a link between CD3- and CD59-mediated signaling pathways in Jurkat T cells

    International Nuclear Information System (INIS)

    Lipp, A. M.

    2012-01-01

    Elevation of intracellular free calcium concentration ([Ca2+]i) is a key signal during T cell activation and is commonly used as a read-out parameter for stimulation of T cell signaling. Upon T cell stimulation a variety of calcium signals is produced by individual cells of the T cell population and the type of calcium signal strongly influences cell fate decisions. The heterogeneous nature of T cells is masked in ensemble measurements, which highlights the need for single-cell measurements. In this study we used single-cell calcium measurements in Jurkat cells to investigate signaling pathways, which are triggered by different proteins, namely CD3 and CD59. By application of an automated cluster algorithm the presented assay provides unbiased analysis of a large data set of individual calcium time traces generated by the whole cell population. By using this method we could demonstrate that the Jurkat population generates heterogeneous calcium signals in a stimulus-dependent manner. Furthermore, our data revealed the existence of a link between CD3- and CD59-mediated signaling pathways. Single-cell calcium measurements in Jurkat cells expressing different levels of the T cell receptor (TCR) complex indicated that CD59-mediated calcium signaling is critically dependent on TCR surface expression levels. In addition, triggering CD59-mediated calcium signaling resulted in down-regulation of TCR surface expression levels, which is known to happen upon direct TCR triggering too. Moreover, by using siRNA-mediated protein knock-downs and protein knock-out Jurkat mutants we could show that CD3- and CD59-mediated calcium signaling require identical key proteins. We therefore explored by which mechanism CD59-mediated signaling couples into TCR-mediated signaling. Fluorescence recovery after photobleaching (FRAP) experiments and live-cell protein-protein interaction assays provided no evidence of a direct physical interaction between CD3- and CD59-mediated signaling pathways

  1. ORA59 and EIN3 interaction couples jasmonate-ethylene synergistic action to antagonistic salicylic acid regulation of PDF expression.

    Science.gov (United States)

    He, Xiang; Jiang, Jishan; Wang, Chang-Quan; Dehesh, Katayoon

    2017-04-01

    Hormonal crosstalk is central for tailoring plant responses to the nature of challenges encountered. The role of antagonism between the two major defense hormones, salicylic acid (SA) and jasmonic acid (JA), and modulation of this interplay by ethylene (ET) in favor of JA signaling pathway in plant stress responses is well recognized, but the underlying mechanism is not fully understood. Here, we show the opposing function of two transcription factors, ethylene insensitive3 (EIN3) and EIN3-Like1 (EIL1), in SA-mediated suppression and JA-mediated activation of PLANT DEFENSIN1.2 (PDF1.2). This functional duality is mediated via their effect on protein, not transcript levels of the PDF1.2 transcriptional activator octadecanoid-responsive Arabidopsis59 (ORA59). Specifically, JA induces ORA59 protein levels independently of EIN3/EIL1, whereas SA reduces the protein levels dependently of EIN3/EIL1. Co-infiltration assays revealed nuclear co-localization of ORA59 and EIN3, and split-luciferase together with yeast-two-hybrid assays established their physical interaction. The functional ramification of the physical interaction is EIN3-dependent degradation of ORA59 by the 26S proteasome. These findings allude to SA-responsive reduction of ORA59 levels mediated by EIN3 binding to and targeting of ORA59 for degradation, thus nominating ORA59 pool as a coordination node for the antagonistic function of ET/JA and SA. © 2017 Institute of Botany, Chinese Academy of Sciences.

  2. Phosphorylation of SAF-A/hnRNP-U Serine 59 by Polo-Like Kinase 1 Is Required for Mitosis.

    Science.gov (United States)

    Douglas, Pauline; Ye, Ruiqiong; Morrice, Nicholas; Britton, Sébastien; Trinkle-Mulcahy, Laura; Lees-Miller, Susan P

    2015-08-01

    Scaffold attachment factor A (SAF-A), also called heterogenous nuclear ribonuclear protein U (hnRNP-U), is phosphorylated on serine 59 by the DNA-dependent protein kinase (DNA-PK) in response to DNA damage. Since SAF-A, DNA-PK catalytic subunit (DNA-PKcs), and protein phosphatase 6 (PP6), which interacts with DNA-PKcs, have all been shown to have roles in mitosis, we asked whether DNA-PKcs phosphorylates SAF-A in mitosis. We show that SAF-A is phosphorylated on serine 59 in mitosis, that phosphorylation requires polo-like kinase 1 (PLK1) rather than DNA-PKcs, that SAF-A interacts with PLK1 in nocodazole-treated cells, and that serine 59 is dephosphorylated by protein phosphatase 2A (PP2A) in mitosis. Moreover, cells expressing SAF-A in which serine 59 is mutated to alanine have multiple characteristics of aberrant mitoses, including misaligned chromosomes, lagging chromosomes, polylobed nuclei, and delayed passage through mitosis. Our findings identify serine 59 of SAF-A as a new target of both PLK1 and PP2A in mitosis and reveal that both phosphorylation and dephosphorylation of SAF-A serine 59 by PLK1 and PP2A, respectively, are required for accurate and timely exit from mitosis. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  3. Production, purification, sequencing and activity spectra of mutacins D-123.1 and F-59.1.

    Science.gov (United States)

    Nicolas, Guillaume G; LaPointe, Gisèle; Lavoie, Marc C

    2011-04-10

    The increase in bacterial resistance to antibiotics impels the development of new anti-bacterial substances. Mutacins (bacteriocins) are small antibacterial peptides produced by Streptococcus mutans showing activity against bacterial pathogens. The objective of the study was to produce and characterise additional mutacins in order to find new useful antibacterial substances. Mutacin F-59.1 was produced in liquid media by S. mutans 59.1 while production of mutacin D-123.1 by S. mutans 123.1 was obtained in semi-solid media. Mutacins were purified by hydrophobic chromatography. The amino acid sequences of the mutacins were obtained by Edman degradation and their molecular mass was determined by mass spectrometry. Mutacin F-59.1 consists of 25 amino acids, containing the YGNGV consensus sequence of pediocin-like bacteriocins with a molecular mass calculated at 2719 Da. Mutacin D-123.1 has an identical molecular mass (2364 Da) with the same first 9 amino acids as mutacin I. Mutacins D-123.1 and F-59.1 have wide activity spectra inhibiting human and food-borne pathogens. The lantibiotic mutacin D-123.1 possesses a broader activity spectrum than mutacin F-59.1 against the bacterial strains tested. Mutacin F-59.1 is the first pediocin-like bacteriocin identified and characterised that is produced by Streptococcus mutans. Mutacin D-123.1 appears to be identical to mutacin I previously identified in different strains of S. mutans.

  4. Class Room Exercises Using JMA-59-Type Seismograms for Earthquake Study at High-School Level

    Science.gov (United States)

    Okamoto, Y.; Furuta, S.; Hirota, N.

    2013-12-01

    The JMA-59-type electromagnetic seismograph was the standard seismograph for routine observations by the Japan Meteorological Agency (JMA) from the 1960's to the 1990's. Some features of those seismograms include 1) displacement wave records (electrically integrated from a velocity output by a moving-coil-type sensor), 2) ink records on paper (analog recording with time marks), 3) continuous drum recording for 12 h, and 4) lengthy operation time over several decades. However, the digital revolution in recording systems during the 1990's made these analog features obsolete, and their abundant and bulky paper-based records were stacked and sometimes disregarded in the library of every observatory. Interestingly, from an educational aspect, the disadvantages of these old-fashioned systems become highly advantageous for educational or outreach purposes. The updated digital instrument is essentially a 'black-box,' not revealing its internal mechanisms and being too fast for observing its signal processes. While the old seismometers and recording systems have been disposed of long since, stacks of analog seismograms continue to languish in observatories' back rooms. In our study, we develop some classroom exercises for studying earthquakes at the mid- to high-school level using these analog seismograms. These exercises include 1) reading the features of seismic records, 2) measuring the S-P time, 3) converting the hypocentral distance from Omori's distance formula, 4) locating the epicenter/hypocenter using the S-P times of surrounding stations, and 5) estimating earthquake magnitude using the Tsuboi's magnitude formula. For this calculation we developed a 'nomogram'--a graphical paper calculator created using a Python-based freeware tool named 'PyNomo.' We tested many seismograms and established the following rules: 1) shallow earthquakes are appropriate for using the Tsuboi's magnitude formula; 2) there is no saturation at peak amplitude; 3) seismograms make it easy to

  5. Weight Estimation Tool for Children Aged 6 to 59 Months in Limited-Resource Settings.

    Science.gov (United States)

    Ralston, Mark E; Myatt, Mark A

    2016-01-01

    A simple, reliable anthropometric tool for rapid estimation of weight in children would be useful in limited-resource settings where current weight estimation tools are not uniformly reliable, nearly all global under-five mortality occurs, severe acute malnutrition is a significant contributor in approximately one-third of under-five mortality, and a weight scale may not be immediately available in emergencies to first-response providers. To determine the accuracy and precision of mid-upper arm circumference (MUAC) and height as weight estimation tools in children under five years of age in low-to-middle income countries. This was a retrospective observational study. Data were collected in 560 nutritional surveys during 1992-2006 using a modified Expanded Program of Immunization two-stage cluster sample design. Locations with high prevalence of acute and chronic malnutrition. A total of 453,990 children met inclusion criteria (age 6-59 months; weight ≤ 25 kg; MUAC 80-200 mm) and exclusion criteria (bilateral pitting edema; biologically implausible weight-for-height z-score (WHZ), weight-for-age z-score (WAZ), and height-for-age z-score (HAZ) values). Weight was estimated using Broselow Tape, Hong Kong formula, and database MUAC alone, height alone, and height and MUAC combined. Mean percentage difference between true and estimated weight, proportion of estimates accurate to within ± 25% and ± 10% of true weight, weighted Kappa statistic, and Bland-Altman bias were reported as measures of tool accuracy. Standard deviation of mean percentage difference and Bland-Altman 95% limits of agreement were reported as measures of tool precision. Database height was a more accurate and precise predictor of weight compared to Broselow Tape 2007 [B], Broselow Tape 2011 [A], and MUAC. Mean percentage difference between true and estimated weight was +0.49% (SD = 10.33%); proportion of estimates accurate to within ± 25% of true weight was 97.36% (95% CI 97.40%, 97.46%); and

  6. Laparoscopic sleeve gastrectomy in patients over 59 years: early recovery and 12-month follow-up.

    Science.gov (United States)

    Leivonen, Marja Kaarina; Juuti, Anne; Jaser, Nabil; Mustonen, Harri

    2011-08-01

    Bariatric surgery has shown to be safe for patients over 60 years with good results especially considering resolving of comorbidities. Sleeve gastrectomy is considered to be safer than gastric bypass (GBP) and more effective than gastric banding with less adverse symptoms. Weight loss may be more modest than after GBP, but the effect on vitamins may also be milder. Since 2007, we collected prospectively 12-month follow-up data from 55 sleeve gastrectomy patients of whom 12 were over 59 years of age. Vitamin and calcium supplements were used postoperatively. The recovery from the operation was recorded during hospital stay, at 1- and 12-month follow-up visits using a standard protocol including laboratory tests. The results between patients over and under 59 years were compared. The preoperative weight and weight loss were comparable between the groups. Operation time was shorter and hospital stay was longer for older patients, p = ns. There was no operative mortality. Early major complications were seen more often in the older age group, 42% vs 9% (p = 0.02), but late complications were more common in younger patients, 17% vs 44%, p = ns. Early complications were mostly bleedings, which did not lengthen the hospital stay, neither were re-operations nor endoscopic procedures needed. Excess weight loss and resolving of comorbidities after 12 months was comparable between the groups. However, vitamin deficiencies and hypoalbuminemia were more common in the older age group, 42% and 23% for vitamins and 44% and 29% for proteins, p = ns. The older patients had more adverse effects related to surgery, 25% vs 9%, and younger had more adverse psychiatric effects, p = ns. Sleeve gastrectomy is effective and safe for older bariatric patients. Weight loss is comparable to younger patients and enough to resolve the comorbidities in most of the patients. With standardized nutritional supplementation, the older patients had more often vitamin deficiencies and

  7. Vaccine adjuvant MF59 promotes the intranodal differentiation of antigen-loaded and activated monocyte-derived dendritic cells.

    Directory of Open Access Journals (Sweden)

    Rossella Cioncada

    Full Text Available MF59 is an oil-in-water emulsion adjuvant approved for human influenza vaccination in European Union. The mode of action of MF59 is not fully elucidated yet, but results from several years of investigation indicate that MF59 establishes an immunocompetent environment at injection site which promotes recruitment of immune cells, including antigen presenting cells (APCs, that are facilitated to engulf antigen and transport it to draining lymph node (dLN where the antigen is accumulated. In vitro studies showed that MF59 promotes the differentiation of monocytes to dendritic cells (Mo-DCs. Since after immunization with MF59, monocytes are rapidly recruited both at the injection site and in dLN and appear to have a morphological change toward a DC-like phenotype, we asked whether MF59 could play a role in inducing differentiation of Mo-DC in vivo. To address this question we immunized mice with the auto-fluorescent protein Phycoerythrin (PE as model antigen, in presence or absence of MF59. We measured the APC phenotype and their antigen uptake within dLNs, the antigen distribution within the dLN compartments and the humoral response to PE. In addition, using Ovalbumin as model antigen, we measured the capacity of dLN APCs to induce antigen-specific CD4 T cell proliferation. Here, we show, for the first time, that MF59 promotes differentiation of Mo-DCs within dLNs from intranodal recruited monocytes and we suggest that this differentiation could take place in the medullary compartment of the LN. In addition we show that the Mo-DC subset represents the major source of antigen-loaded and activated APCs within the dLN when immunizing with MF59. Interestingly, this finding correlates with the enhanced triggering of antigen-specific CD4 T cell response induced by LN APCs. This study therefore demonstrates that MF59 is able to promote an immunocompetent environment also directly within the dLN, offering a novel insight on the mechanism of action of

  8. Bilateral Primary Adrenal Lymphoma in a 59- year-old Female

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    Alireza Ahmadi

    2018-02-01

    Full Text Available Occasionally, lymphoma involves the adrenal glands; however, primary adrenal lymphoma (PAL is rare and only few cases have been reported. We report a case of a 59-year-old female with primary adrenal diffuse large B-cell lymphoma (DLBCL manifested by weakness, fatigue, anorexia, and hyper pigmentation of skin. The patient initially responded to intravenous hydrocortisone in large doses by total remission of the symptoms. An abdominal computed tomography scan showed a hypodense mass in the right subdiaphragmatic space, which was suggestive of an adrenal gland tumor with adjacent liver involvement. Additionally, a smaller lesion with similar characteristics was found in the left adrenal gland. The results obtained from adrenal gland needle biopsy confirmed the diagnosis of DLBCL. Moreover, primary laboratory findings demonstrated hyponatremia, hyperkalemia, fasting blood sugar level of 153 mg/dl, and alkaline phosphatase level of 663 U/L. The mentioned symptoms and laboratory findings were indicative of adrenal insufficiency. After about 2 months, her level of consciousness decreased and urinary and fecal incontinence occurred. Therefore, brain involvement was suspected, and magnetic resonance imaging of the brain showed heterogeneous enhancement (24.8 mm in the posterior aspect of the left temporal lobe together with patchy foci of enhancement in around the ventricular areas of the brain that showed metastatic lesions of PAL. This case should remind clinicians that PAL may be a cause of adrenal incidentaloma, especially when the patient presents with the symptoms of adrenal insufficiency.

  9. Source complexity of the May 20, 2012, Mw 5.9, Ferrara (Italy event

    Directory of Open Access Journals (Sweden)

    Davide Piccinini

    2012-10-01

    Full Text Available A Mw 3.9 foreshock on May 19, 2012, at 23:13 UTC, was followed at 02:03 on May 20, 2012, by a Mw 5.9 earthquake that hit a densely populated area in the Po Plain, west of the city of Ferrara, Italy (Figure 1. Over the subsequent 13 days, six Mw >5 events occurred; of these, the most energetic was a Mw 5.8 earthquake on May 29, 2012, 12 km WSW of the main shock. The tragic balance of this sequence was 17 casualties, hundreds of injured, and severe damage to the historical and cultural heritage of the area. From a seismological point of view, the 2012 earthquake was not an outstanding event in its regional context. The same area was hit in 1996 by a Mw 5.4 earthquake [Selvaggi et al. 2001], and previously in 1986 and in 1967 (DBMI11 [Locati et al. 2011]. The most destructive historical event was the 1570, Imax 8 event, which struck the town of Ferrara [Guidoboni et al. 2007, Rovida et al. 2011]. The 2012 seismic sequence lasted for several weeks and probably developed on a well-known buried thrust fault [Basili et al. 2008, Toscani et al. 2009, DISS Working Group 2010], at depths between 2 km and 10-12 km. […

  10. 10CFR50.59 safety evaluation training and expert system development

    International Nuclear Information System (INIS)

    Kline, S.W.; Dickinson, D.B.

    1988-01-01

    10CFR50.59 permits utilities to make changes to and conduct tests or experiments on operating nuclear power plants without prior US Nuclear Regulatory Commission (NCR) approval unless the proposed change, test, or experiment (i.e, the proposed activity) involves a change to the plant technical specifications or an unreviewed safety question (USQ). To provide guidance to their engineers for making the determination of whether a proposed activity involves a USQ. Bechtel has developed a safety evaluation training program. This training program incorporates the guidance in and NRC comments to the November 1987 draft Nuclear Management and Resources Council safety evaluation guidance document, NRC statements contained in inspection reports and other documents, and the experience of senior Bechtel engineers. To further develop the question and concerns that need to be addressed in a safety evaluation in a systematic manner, Bechtel is incorporating the training program guidance and other information into an IBM PC-AT-based working model of an expert system using the NEXPERT expert system development tool. The development and use of this expert system working model are being undertaken to provide consistency and completeness to the thought process used and the output provided by Bechtel engineers when performing a safety evaluation

  11. C5 Palsy After Cervical Spine Surgery: A Multicenter Retrospective Review of 59 Cases.

    Science.gov (United States)

    Thompson, Sara E; Smith, Zachary A; Hsu, Wellington K; Nassr, Ahmad; Mroz, Thomas E; Fish, David E; Wang, Jeffrey C; Fehlings, Michael G; Tannoury, Chadi A; Tannoury, Tony; Tortolani, P Justin; Traynelis, Vincent C; Gokaslan, Ziya; Hilibrand, Alan S; Isaacs, Robert E; Mummaneni, Praveen V; Chou, Dean; Qureshi, Sheeraz A; Cho, Samuel K; Baird, Evan O; Sasso, Rick C; Arnold, Paul M; Buser, Zorica; Bydon, Mohamad; Clarke, Michelle J; De Giacomo, Anthony F; Derakhshan, Adeeb; Jobse, Bruce; Lord, Elizabeth L; Lubelski, Daniel; Massicotte, Eric M; Steinmetz, Michael P; Smith, Gabriel A; Pace, Jonathan; Corriveau, Mark; Lee, Sungho; Cha, Peter I; Chatterjee, Dhananjay; Gee, Erica L; Mayer, Erik N; McBride, Owen J; Roe, Allison K; Yanez, Marisa Y; Stroh, D Alex; Than, Khoi D; Riew, K Daniel

    2017-04-01

    A multicenter, retrospective review of C5 palsy after cervical spine surgery. Postoperative C5 palsy is a known complication of cervical decompressive spinal surgery. The goal of this study was to review the incidence, patient characteristics, and outcome of C5 palsy in patients undergoing cervical spine surgery. We conducted a multicenter, retrospective review of 13 946 patients across 21 centers who received cervical spine surgery (levels C2 to C7) between January 1, 2005, and December 31, 2011, inclusive. P values were calculated using 2-sample t test for continuous variables and χ 2 tests or Fisher exact tests for categorical variables. Of the 13 946 cases reviewed, 59 patients experienced a postoperative C5 palsy. The incidence rate across the 21 sites ranged from 0% to 2.5%. At most recent follow-up, 32 patients reported complete resolution of symptoms (54.2%), 15 had symptoms resolve with residual effects (25.4%), 10 patients did not recover (17.0%), and 2 were lost to follow-up (3.4%). C5 palsy occurred in all surgical approaches and across a variety of diagnoses. The majority of patients had full recovery or recovery with residual effects. This study represents the largest series of North American patients reviewed to date.

  12. Proton beam dosimetry for radiosurgery: implementation of the ICRU Report 59 at the Harvard Cyclotron Laboratory

    International Nuclear Information System (INIS)

    Newhauser, Wayne D.; Myers, Karla D.; Rosenthal, Stanley J.; Smith, Alfred R.

    2002-01-01

    Recent proton dosimetry intercomparisons have demonstrated that the adoption of a common protocol, e.g. ICRU Report 59, can lead to improved consistency in absorbed dose determinations. We compared absorbed dose values, measured in the 160 MeV proton radiosurgery beamline at the Harvard Cyclotron Laboratory, based on ionization chamber methods with those from a Faraday cup technique. The Faraday cup method is based on a proton fluence determination that allows the estimation of absorbed dose with the CEMA approximation, under which the dose is equal to the fluence times the mean mass stopping power. The ionization chamber technique employs an air-kerma calibration coefficient for 60 Co radiation and a calculated correction in order to take into account the differences in response to 60 Co and proton beam radiations. The absorbed dose to water, based on a diode measurement calibrated with a Faraday cup technique, is approximately 2% higher than was obtained from an ionization chamber measurement. At the Bragg peak depth, the techniques agree to within their respective uncertainties, which are both approximately 4% (1 standard deviation). The ionization chamber technique exhibited superior reproducibility and was adopted in our standard clinical practice for radiosurgery. (author)

  13. [Drinking behaviors and patterns among floating population aged 18-59 years old in China, 2012].

    Science.gov (United States)

    Li, Yichong; Zhang, Mei; Jiang, Yong; Deng, Qian; Zhao, Yinjun; Huang, Zhengjing; Zeng, Xinying; Wang, Limin

    2014-11-01

    To understand the drinking behaviors and patterns among floating population in China. Floating population were selected through multistage clustering sampling method, stratified by 6 major industries in 170 counties and districts from 31 provinces/autonomous regions, and Xinjiang Construction Corps, in mainland China. Design-based methods were adopted to analyze the drinking behavior in subpopulations. A total of 48 697 floating population aged 18-59 years were included in the study. The overall prevalence rate of drinking was 51.7% with 71.9% in men and 24.7% in women, in the last 12 months. Among those who ever drank, the weekly drinking prevalence and daily alcohol intake were 53.9% and 18.7 g in males while 16.7% and 4.1 g in females, respectively, among those floating population. Weekly drinking prevalence rates, for both genders, increased along with the increase of age (P population from the construction industry had the highest prevalence rates on items as weekly drinking, daily alcohol intake and prevalence of unhealthy drinking behaviors, except for hazardous drinking behaviors. Drinking behavior was prevalent among floating population in China. Significant difference was seen between genders. Unhealthy drinking behaviors varied greatly among male drinkers at different age groups or education levels as well as among those working in the different industries.

  14. Prognostic significance of new immunohistochemical markers in refractory classical Hodgkin lymphoma: a study of 59 cases.

    Directory of Open Access Journals (Sweden)

    Danielle Canioni

    2009-07-01

    Full Text Available Although most classical Hodgkin lymphoma patients are cured, a significant minority fail after primary therapy and may die as result of their disease. To date, there is no consensus on biological markers that add value to usual parameters (which comprise the International Prognostic Score used at diagnosis to predict outcome. We evaluated 59 patients (18 with primary refractory or early relapse disease and 41 responders for bcl2, Ki67, CD20, TiA1 and c-kit expression by semi-quantitative immunohistochemical study and correlated the results with the response to treatment.The results showed that expression of bcl2 and CD20 in Hodgkin and Reed Sternberg cells, and expression of TiA1 in micro-environmental lymphocytes, and c-kit positive mast cells in microenvironment, were independent prognostic markers. These novel cHL markers could be used in association with clinical parameters to identify newly diagnosed patients with favorable or unfavorable prognosis and to better tailor treatment for different risk groups.

  15. Risk Factors of Underweight in Children Aged 6–59 Months in Ethiopia

    Directory of Open Access Journals (Sweden)

    Deneke Tosheno

    2017-01-01

    Full Text Available Background. Undernutrition in early childhood has irreversible and long-lasting implications. Hence, this study was aimed at assessing risk factors of child undernutrition. Methods. A community-based cross-sectional study was conducted on 642 households with mothers to children pairs aged 6–59 months selected by a multistage systematic random sampling method. Child anthropometric measurements on weight were recorded using standardized and calibrated weighing scales. Weight-for-age was compared to the 2007 WHO growth reference by WHO Anthro software. Data were entered using Epi-Info and analyzed using SPSS. Bivariate and multivariate logistic regression analyses were used to evaluate the association between underweight children and their predictors; both crude and adjusted odds ratios with 95% confidence interval were reported. Results. One-fourth (25% of the children were underweight. Child age (AOR: 2.36, gender (AOR: 1.82, illness (AOR: 0.09, maternal decision making power (AOR: 0.07, maternal education (AOR: 0.19, employment/occupation (AOR: 5.29, and household income (AOR: 4.16 were found to be independent and significant predictors of underweight children. Conclusion. Significant proportion of the children were underweight. Maternal decision-making power persists as a strong predictor of children’s weight. Therefore, intervention programs focusing on improving mothers’ decision-making power on child nutrition would contribute to the efforts towards alleviating the problem.

  16. Do hormonal contraceptives stimulate growth of neurofibromas? A survey on 59 NF1 patients

    International Nuclear Information System (INIS)

    Lammert, Marge; Mautner, Victor-Felix; Kluwe, Lan

    2005-01-01

    Neurofibromas are benign tumors of the peripheral nerves and hallmark of neurofibromatosis type 1 (NF1), a tumor suppressor gene syndrome. Neurofibromas mostly start developing at puberty and can increase in size and number during pregnancy. Expression of progesterone receptors has been found in 75% of the tumors. Many female NF1 patients are thus concerned about the possibility that hormonal contraceptives may stimulate the growth of their neurofibromas. A survey was carried out on 59 female NF1 patients who are practicing or have practiced hormonal contraception to examine the effect of the various contraceptives on the growth of neurofibromas. Majority (53 out of 58) of patients who received oral estrogen-progestogen or pure progestogen preparations reported no associated tumor growth. In contrast, significant tumor growth was reported by two patients who received depot contraceptive containing high dose of synthetic progesterone. Oral contraceptives do not seem to stimulate the growth of neurofibromas in NF1 patients. High doses of progesterone might stimulate the growth of neurofibromas and deserve more caution

  17. Syndromes of collateral-reported psychopathology for ages 18-59 in 18 Societies

    Science.gov (United States)

    Ivanova, Masha Y.; Achenbach, Thomas M.; Rescorla, Leslie A.; Turner, Lori V.; Árnadóttir, Hervör Alma; Au, Alma; Caldas, J. Carlos; Chaalal, Nebia; Chen, Yi Chuen; da Rocha, Marina M.; Decoster, Jeroen; Fontaine, Johnny R.J.; Funabiki, Yasuko; Guðmundsson, Halldór S.; Kim, Young Ah; Leung, Patrick; Liu, Jianghong; Malykh, Sergey; Marković, Jasminka; Oh, Kyung Ja; Petot, Jean-Michel; Samaniego, Virginia C.; Silvares, Edwiges Ferreira de Mattos; Šimulionienė, Roma; Šobot, Valentina; Sokoli, Elvisa; Sun, Guiju; Talcott, Joel B.; Vázquez, Natalia; Zasępa, Ewa

    2017-01-01

    The purpose was to advance research and clinical methodology for assessing psychopathology by testing the international generalizability of an 8-syndrome model derived from collateral ratings of adult behavioral, emotional, social, and thought problems. Collateral informants rated 8,582 18–59-year-old residents of 18 societies on the Adult Behavior Checklist (ABCL). Confirmatory factor analyses tested the fit of the 8-syndrome model to ratings from each society. The primary model fit index (Root Mean Square Error of Approximation) showed good model fit for all societies, while secondary indices (Tucker Lewis Index, Comparative Fit Index) showed acceptable to good fit for 17 societies. Factor loadings were robust across societies and items. Of the 5,007 estimated parameters, 4 (0.08%) were outside the admissible parameter space, but 95% confidence intervals included the admissible space, indicating that the 4 deviant parameters could be due to sampling fluctuations. The findings are consistent with previous evidence for the generalizability of the 8-syndrome model in self-ratings from 29 societies, and support the 8-syndrome model for operationalizing phenotypes of adult psychopathology from multi-informant ratings in diverse societies. PMID:29399019

  18. A Noncellulosomal Mannanase26E Contains a CBM59 in Clostridium cellulovorans

    Directory of Open Access Journals (Sweden)

    Kosuke Yamamoto

    2014-01-01

    Full Text Available A multicomponent enzyme-complex prevents efficient degradation of the plant cell wall for biorefinery. In this study, the method of identifying glycoside hydrolases (GHs to degrade hemicelluloses was demonstrated. The competence of C. cellulovorans, which changes to be suitable for degradation of each carbon source, was used for the method. C. cellulovorans was cultivated into locust bean gum (LBG that is composed of galactomannan. The proteins produced by C. cellulovorans were separated into either fractions binding to crystalline cellulose or not. Proteins obtained from each fraction were further separated by SDS-PAGE and were stained with Coomassie Brilliant Blue and were detected for mannanase activity. The proteins having the enzymatic activity for LBG were cut out and were identified by mass spectrometry. As a result, four protein bands were classified into glycosyl hydrolase family 26 (GH26 mannanases. One of the identified mannanases, Man26E, contains a carbohydrate-binding module (CBM family 59, which binds to xylan, mannan, and Avicel. Although mannose and galactose are the same as a hexose, the expression patterns of the proteins from C. cellulovorans were quite different. More interestingly, zymogram for mannanase activity showed that Man26E was detected in only LBG medium.

  19. Cardiovascular risk factors and cognitive function in adults 30-59 years of age (NHANES III).

    Science.gov (United States)

    Pavlik, Valory N; Hyman, David J; Doody, Rachelle

    2005-01-01

    In the Third National Health and Nutrition Examination Survey (NHANES III), three measures of cognitive function [Simple Reaction Time Test (SRTT), Symbol Digit Substitution Test (SDST), and Serial Digit Learning Test (SDLT)] were administered to a half-sample of 3,385 adult men and nonpregnant women 30-59 years of age with no history of stroke. We used multiple linear regression analysis to determine whether there was an independent association between performance on each cognitive function measure and defined hypertension (HTN) alone, type 2 diabetes mellitus (DM) alone, and coexistent HTN and DM after adjustment for demographic and socioeconomic variables and selected health behaviors. After adjustment for the sociodemographic variables, the combination of HTN + DM, but not HTN alone or DM alone, was significantly associated with worse performance on the SRTT (p = 0.031) and the SDST (p = 0.011). A similar pattern was observed for SDLT performance, but the relationship did not reach statistical significance (p = 0.101). We conclude that HTN in combination with DM is associated with detectable cognitive decrements in persons under age 60.

  20. LNG containment release: Comparison of NFPA-59A and 49-CFR-193

    International Nuclear Information System (INIS)

    West, H.H.; Pfenning, D.B.

    1994-01-01

    Due to the potential wide area impact of an unplanned LNG (Liquefied Natural Gas) release, the National Fire Protection Association (NFPA) and later the US Department of Transportation issued standards and regulations which included specific methodologies for analyzing the consequence of an accidental LNG release. The concept of a ''design spill'' was defined in order to evaluate the consequences of an accidental LNG release, with particular attention to the influence of safety protective measures. In addition to specifying the magnitude of the unplanned release, the design spill also specified some of the parameters for estimation of the downwind LNG vapor dispersion and the extent of the radiant heat from an LNG pool fire. Since the NFPA-59A and 49-CFR-193 standards were the first in-depth regulation to address consequence analysis estimation for petroleum components, it is particularly important to consider their details in light of the recently proposed EPA 40-CFR-68 regulations [Risk Management for Chemical Accidental Release Prevention] which specifically address consequence analysis as a part of process safety management

  1. Photoneutron cross sections for {sup 59}Co. Systematic uncertainties of data from various experiments

    Energy Technology Data Exchange (ETDEWEB)

    Varlamov, V.V. [Lomonosov Moscow State University, Skobeltsyn Institute of Nuclear Physics, Moscow (Russian Federation); Davydov, A.I. [Lomonosov Moscow State University, Physics Faculty, Moscow (Russian Federation); Ishkhanov, B.S. [Lomonosov Moscow State University, Skobeltsyn Institute of Nuclear Physics, Moscow (Russian Federation); Lomonosov Moscow State University, Physics Faculty, Moscow (Russian Federation)

    2017-09-15

    Data on partial photoneutron reaction cross sections (γ, 1n), (γ, 2n), and (γ, 3n) for {sup 59}Co obtained in two experiments carried out at Livermore (USA) were analyzed. The sources of radiation in both experiments were the monoenergetic photon beams from the annihilation in flight of relativistic positrons. The total yield was sorted by the neutron multiplicity, taking into account the difference in the neutron energy spectra for different multiplicity. The two quoted studies differ in the method of determining the neutron. Significant systematic disagreements between the results of the two experiments exist. They are considered to be caused by large systematic uncertainties in partial cross sections, since they do not satisfy physical criteria for reliability of the data. To obtain reliable cross sections of partial and total photoneutron reactions a new method combining experimental data and theoretical evaluation was used. It is based on the experimental neutron yield cross section which is rather independent of neutron multiplicity and the transitional neutron multiplicity functions of the combined photonucleon reaction model (CPNRM). The model transitional multiplicity functions were used for the decomposition of the neutron yield cross section into the contributions of partial reactions. The results of the new evaluation noticeably differ from the partial cross sections obtained in the two experimental studies are under discussion. (orig.)

  2. Comparative silicone breast implant evaluation using mammography, sonography, and magnetic resonance imaging: experience with 59 implants.

    Science.gov (United States)

    Ahn, C Y; DeBruhl, N D; Gorczyca, D P; Shaw, W W; Bassett, L W

    1994-10-01

    With the current controversy regarding the safety of silicone implants, the detection and evaluation of implant rupture are causing concern for both plastic surgeons and patients. Our study obtained comparative value analysis of mammography, sonography, and magnetic resonance imaging (MRI) in the detection of silicone implant rupture. Twenty-nine symptomatic patients (total of 59 silicone implants) were entered into the study. Intraoperative findings revealed 21 ruptured implants (36 percent). During physical examination, a positive "squeeze test" was highly suggestive of implant rupture. Mammograms were obtained of 51 implants (sensitivity 11 percent, specificity 89 percent). Sonography was performed on 57 implants (sensitivity 70 percent, specificity 92 percent). MRI was performed on 55 implants (sensitivity 81 percent, specificity 92 percent). Sonographically, implant rupture is demonstrated by the "stepladder sign." Double-lumen implants may appear as false-positive results for rupture on sonography. On MRI, the "linguine sign" represents disrupted fragments of a ruptured implant. The most reliable imaging modality for implant rupture detection is MRI, followed by sonogram. Mammogram is the least reliable. Our study supports the clinical indication and diagnostic value of sonogram and MRI in the evaluation of symptomatic breast implant patients.

  3. Predictive factors for mortality in Fournier' gangrene: a series of 59 cases.

    Science.gov (United States)

    García Marín, Andrés; Turégano Fuentes, Fernando; Cuadrado Ayuso, Marta; Andueza Lillo, Juan Antonio; Cano Ballesteros, Juan Carlos; Pérez López, Mercedes

    2015-01-01

    Fournier's gangrene (FG) is the necrotizing fasciitis of the perineum and genital area and presents a high mortality rate. The aim was to assess prognostic factors for mortality, create a new mortality predictive scale and compare it with previously published scales in patients diagnosed with FG in our Emergency Department. Retrospective analysis study between 1998 and 2012. Of the 59 patients, 44 survived (74%) (S) and 15 died (26%) (D). Significant differences were found in peripheral vasculopathy (S 5 [11%]; D 6 [40%]; P=.023), hemoglobin (S 13; D 11; P=.014), hematocrit (S 37; D 31.4; P=.009), white blood cells (S 17,400; D 23,800; P=.023), serum urea (S 58; D 102; PFournier's gangrene severity index score (FGSIS) (S 4; D 7; P=.002) and Uludag Fournier's Gangrene Severity Index (UFGSI) (S 9; D 13; P=.004). Independent predictive factors were peripheral vasculopathy, serum potassium and severe sepsis criteria, and a model was created with an area under the ROC curve of 0.850 (0.760-0.973), higher than FGSIS (0.746 [0.601-0.981]) and UFGSI (0.760 [0.617-0.904]). FG showed a high mortality rate. Independent predictive factors were peripheral vasculopathy, potassium and severe sepsis criteria creating a predictive model that performed better than those previously described. Copyright © 2014 AEC. Publicado por Elsevier España, S.L.U. All rights reserved.

  4. Insights into the 1.59-Mbp largest plasmid of Azospirillum brasilense CBG497.

    Science.gov (United States)

    Acosta-Cruz, Erika; Wisniewski-Dyé, Florence; Rouy, Zoé; Barbe, Valérie; Valdés, María; Mavingui, Patrick

    2012-09-01

    The plant growth-promoting proteobacterium Azospirillum brasilense enhances growth of many economically important crops, such as wheat, maize, and rice. The sequencing and annotation of the 1.59-Mbp replicon of A. brasilense CBG497, a strain isolated from a maize rhizosphere grown on an alkaline soil in the northeast of Mexico, revealed a GC content of 68.7 % and the presence of 1,430 potential protein-encoding genes, 1,147 of them classified into clusters of orthologous groups categories, and 16 tRNA genes representing 11 tRNA species. The presence of sixty-two genes representatives of the minimal gene set and chromid core genes suggests its importance in bacterial survival. The phaAB → G operon, reported as involved in the bacterial adaptation to alkaline pH in the presence of K(+), was also found on this replicon and detected in several Azospirillum strains. Phylogenetic analysis suggests that it was laterally acquired. We were not able to show its inference on the adaptation to basic pH, giving a hint about the presence of an alternative system for adaptation to alkaline pH.

  5. Study on iron metabolism in children using double labelling of 51Cr and 59Fe

    International Nuclear Information System (INIS)

    Kobayashi, Masatsura

    1974-01-01

    In the children before and after treatment for iron deficiency anemia and those on ingesting a long-term low caloric and iron diet, life span of Ashby Technique 1/2(AST) red cells, circulatory blood volume (CBV), plasma iron disappearance(PID), red cell-iron utility(RCIU), plasma-iron turnover rate(PITR), and red cell-ironturnover rate(RCITR) were respectively determined using double labeling of 51 Cr and 59 Fe, and the following results and conclusions were obtained: In the patients with iron deficiency anemia, the rate of RCIU was highly increased, and simultaneously the shortening in AST was observed. Among the children with the iron deficiency anemia, five patients were examined immediately after the improvement on the anemia by iron drugs; the serum iron (SFe) averaged 74μg/ml. So the erthropiesis appeared to recover to normal, yet AST has hardly changed, still more has it shortened. In five children with celebral palsy associated with disturbance of physical development, who had ingested a long-term liquid low iron diet no evident increase of RCIU was found except for high calues of RCITR. The shortening in AST was not entirely seen in contrast with that of the simple alimentary iron deficiency anemia. Besides the CBV measured par kg of weight showed the remarkable increase. (Oyama, S.)

  6. Photometric search for variable stars in the young open cluster Berkeley 59

    Science.gov (United States)

    Lata, Sneh; Pandey, A. K.; Maheswar, G.; Mondal, Soumen; Kumar, Brijesh

    2011-12-01

    We present the time series photometry of stars located in the extremely young open cluster Berkeley 59. Using the 1.04-m telescope at Aryabhatta Research Institute of Observational Sciences (ARIES), Nainital, we have identified 42 variables in a field of ˜13 × 13 arcmin2 around the cluster. The probable members of the cluster have been identified using a (V, V-I) colour-magnitude diagram and a (J-H, H-K) colour-colour diagram. 31 variables have been found to be pre-main-sequence stars associated with the cluster. The ages and masses of the pre-main-sequence stars have been derived from the colour-magnitude diagram by fitting theoretical models to the observed data points. The ages of the majority of the probable pre-main-sequence variable candidates range from 1 to 5 Myr. The masses of these pre-main-sequence variable stars have been found to be in the range of ˜0.3 to ˜3.5 M⊙, and these could be T Tauri stars. The present statistics reveal that about 90 per cent T Tauri stars have period dispersal of the discs of relatively massive stars.

  7. Midterm results of endovascular treatment of iliac artery lesions: analysis of 59 cases

    Directory of Open Access Journals (Sweden)

    Leonardo Ghizoni Bez

    2013-06-01

    Full Text Available BACKGROUND: Endovascular treatment of peripheral arterial occlusive disease has become increasingly frequent in the past few years. Because it is a less invasive procedure, lower morbidity and mortality rates are associated with this form of treatment. OBJECTIVES: To describe the endovascular procedures performed in iliac arteries for the treatment of peripheral arterial occlusive disease. METHODS: This retrospective study assesses 59 cases of iliac artery angioplasty performed according to a specific protocol from January 2004 to February 2010. RESULTS: Mean age of patients was 62 years (minimum: 42, maximum: 89. Thirty seven were male (62.72% and 22 female (37.28%. The main indications for treatment were moderate to severe intermittent claudication in 30 cases (50.84% and rest pain or trophic lesions (critical ischemia in 29 cases (49.15%. Postoperative follow-up included ankle-brachial index measurements and a duplex ultrasound at 30 days, 3 months, 6 months, 12 months, and every 6 months thereafter. Minimum follow-up time was 3 months, and maximum, 72 months (6 years, with primary and secondary patency rates of 91.37 and 94.82%, respectively. CONCLUSIONS: The results of this case series, combined with literature review results, allow to conclude that the endovascular approach is an effective and safe option to treat peripheral arterial occlusive disease in iliac arteries.

  8. On interaction of zirconium isopropylate with scandium and lanthanum isopropylates. Alkoxozirconates of the scandium subgroup

    International Nuclear Information System (INIS)

    Turova, N.Ya.; Kozlova, N.I.

    1982-01-01

    The solubility in the Zr(OR) 4 -Sc(OR) 3 -THF and Zr(OR) 4 -La(OR) 3 -ROH (R=iso-Pr) at 20 deg was studied. It was ascertained that complex formation did not occur in the first system and LaZr 3 (OR) 15 x3ROH were present in the second one. Complex properties were studied by the methods of IR, PMR spectroscopy, mass-spectrometric and preparative methods. A structure with octahedric coordination of M 3 and Zr atoms was supposed for M 3 Zr 3 (OR) 15 x3L (M=Y, La). Regularities in the change of Sc, Y, La alkoxozirconates were established

  9. Predominance of community-associated sequence type 59 methicillin-resistant Staphylococcus aureus in a paediatric intensive care unit.

    Science.gov (United States)

    Song, Qifa; Wu, Junhua; Ruan, Peisen

    2018-03-01

    To investigate the distribution of molecular types of methicillin-resistant Staphylococcus aureus (MRSA) in a paediatric intensive care unit (PICU) according to their community-associated (CA) and hospital-associated (HA) source of acquisition, and thus assess the degree to which CA-MRSA has been introduced into the PICU. We implemented an MRSA surveillance in a PICU during 2013-2016 and investigated the genetic diversity of the isolates retrospectively using three genetic typing methods, as well as antibiograms and virulence factor profiles.Results/Key findings. From 2684 specimens, we identified 60 MRSA isolates, 43 of which were ST59 CA-MRSA. These 43 ST59 MRSA isolates could be further subtyped into 2 clusters and 7 sporadic isolates by pulsed-field gel electrophoresis, and 3 spa types, which demonstrated the genetic diversity in ST59 MRSA. Phenotypic diversity was also demonstrated among these ST59 MRSA isolates, with 12 virulence factor profiles and 4 antibiograms being identified. Epidemiological information showed that 43 ST59 MRSA isolates were both community-associated (15 isolates) and hospital-associated (28 isolates) and caused colonization and various types of infections in different age groups of children. Our results show that a predominant ST59 CA-MRSA has been introduced into the PICU to a significant extent. This has caused the ST59 HA-MRSA and CA-MRSA in the PICU to be indistinguishable. Our results also demonstrate that when we are interpreting situations where the causative agents of infections focus on very limited pathogenic clones, combined typing methods and epidemiological information are needed to investigate isolates' genetic and phenotypic diversity to distinguish an outbreak from endemic cases.

  10. Identifying Tmem59 related gene regulatory network of mouse neural stem cell from a compendium of expression profiles

    Directory of Open Access Journals (Sweden)

    Guo Xiuyun

    2011-09-01

    Full Text Available Abstract Background Neural stem cells offer potential treatment for neurodegenerative disorders, such like Alzheimer's disease (AD. While much progress has been made in understanding neural stem cell function, a precise description of the molecular mechanisms regulating neural stem cells is not yet established. This lack of knowledge is a major barrier holding back the discovery of therapeutic uses of neural stem cells. In this paper, the regulatory mechanism of mouse neural stem cell (NSC differentiation by tmem59 is explored on the genome-level. Results We identified regulators of tmem59 during the differentiation of mouse NSCs from a compendium of expression profiles. Based on the microarray experiment, we developed the parallelized SWNI algorithm to reconstruct gene regulatory networks of mouse neural stem cells. From the inferred tmem59 related gene network including 36 genes, pou6f1 was identified to regulate tmem59 significantly and might play an important role in the differentiation of NSCs in mouse brain. There are four pathways shown in the gene network, indicating that tmem59 locates in the downstream of the signalling pathway. The real-time RT-PCR results shown that the over-expression of pou6f1 could significantly up-regulate tmem59 expression in C17.2 NSC line. 16 out of 36 predicted genes in our constructed network have been reported to be AD-related, including Ace, aqp1, arrdc3, cd14, cd59a, cds1, cldn1, cox8b, defb11, folr1, gdi2, mmp3, mgp, myrip, Ripk4, rnd3, and sncg. The localization of tmem59 related genes and functional-related gene groups based on the Gene Ontology (GO annotation was also identified. Conclusions Our findings suggest that the expression of tmem59 is an important factor contributing to AD. The parallelized SWNI algorithm increased the efficiency of network reconstruction significantly. This study enables us to highlight novel genes that may be involved in NSC differentiation and provides a shortcut to

  11. Sexuality during pregnancy and after childbirth: a metacontent analysis of 59 studies.

    Science.gov (United States)

    von Sydow, K

    1999-07-01

    The aim of this study is to gain a systematic overview of all existing studies on parental sexuality during pregnancy and the postpartum period (months 1-6). Investigations of psychological and medical data banks and cross-references revealed 59 relevant studies published in English or German between 1950 and 1996. These primary studies were metacontent analyzed, according to the following categories: methodology (samples, designs): type of descriptive data researched (sexual activity, interest, enjoyment, orgasm, problems); and type of correlational data researched (sexual variables and pregnancy outcome, maternal physical and psychological health, sociodemographic data, biographical data, partnership data). On average, female sexual interest and coital activity declines slightly in the first trimester of pregnancy, shows variable patterns in the second trimester, and decreases sharply in the third trimester. Most couples do not practice intercourse for about 2 months around the delivery. Afterwards, sexual interest and activity tends to be reduced for several months as compared with the prepregnancy level, and sexual problems occur relatively often. But most remarkable is the interindividual variability concerning sexual responsiveness, orgasm, activity, and enjoyment. Descriptive research is focused on coital activity of (expectant) mothers. Data about fathers, noncoital activities, and sexual feelings are scarce. Data analysis is focused on three questions: (1) Does sexual activity in pregnancy harm the fetus? (if there are no risk factors: no); (2) Are physical and mental symptoms or data about the delivery and sexual variables correlated? (in some cases: yes); (3) Are sociodemographic data and sexual variables correlated? (mostly not). Research deficits (e.g., conceptual reductionism "sexuality=intercourse," neglect of the male partners, validity, reliability, neglect of the nonsexual partnership and of biographical influences) are critically discussed

  12. Syndromes of collateral-reported psychopathology for ages 18-59 in 18 Societies

    Directory of Open Access Journals (Sweden)

    Masha Y. Ivanova

    2015-01-01

    Full Text Available El objetivo del presente estudio fue avanzar en la metodología clínica y de investigación relativa a la evaluación psicopatológica poniendo a prueba la generalización internacional de un modelo de ocho síndromes derivado de evaluaciones de personas allegadas a adultos sobre los problemas emocionales, sociales y de pensamiento y conducta de dichos adultos. Informantes allegados a los adultos calificaron a 8.582 residentes de 18 países con edades comprendidas entre 18 y 59 años con el Adult Behavior Checklist(ABCL. Mediante un análisis factorial confirmatorio se examinó el ajuste del modelo de ocho síndromes a las puntuaciones provenientes de cada país. El índice primario de ajuste del modelo (RMSEA mostró un buen ajuste del modelo en todos los países, mientras que índices secundarios (Comparative Fit Index Tucker-Lewis Index mostraron un ajuste de aceptable a bueno en 17 países. Se obtuvieron cargas factoriales robustas para los distintos países e ítems. De los 5.007 parámetros estimados, cuatro (0,08 % se encontraban fuera de rango. No obstante, los intervalos de confianza del 95% comprendían el espacio admisible, indicando que la desviación de los cuatro parámetros podría deberse a fluctuaciones en el muestreo. Los hallazgos coinciden con la evidencia previa existente sobre la generalización del modelo de ocho síndromes obtenida de autoinformes realizados en 28 sociedades. Además, los resultados indican que el modelo es adecuado para operacionalizar fenotipos de la psicopatología del adulto a partir de evaluaciones de múltiples informantes en diversas sociedades.

  13. Complications in laparoscopic radical cystectomy: The South American experience with 59 cases

    Directory of Open Access Journals (Sweden)

    Octavio A. Castillo

    2006-06-01

    Full Text Available OBJECTIVE: In this study, we have gathered the second largest series yet published on laparoscopic radical cystectomy in order to evaluate the incidence and cause of intra and postoperative complication, conversion to open surgery, and patient mortality. MATERIALS AND METHODS: From 1997 to 2005, 59 laparoscopic radical cystectomies were performed for the management of bladder cancer at 3 institutions in South America. Twenty nine patients received continent urinary diversion, including 25 orthotopic ileal neobladders and 4 Indiana pouches. Only one case of continent urinary diversion was performed completely intracorporeally. RESULTS: Mean operative time was 337 minutes (150-600. Estimated intraoperative blood loss was 488 mL (50-1500 and 12 patients (20% required blood transfusion. All 7 (12% intraoperative complications were vascular in nature, that is, 1 epigastric vessel injury, 2 injuries to the iliac vessels (1 artery and 1 vein, and 4 bleedings that occurred during the bladder pedicles control. Eighteen (30% postoperative complications (not counting mortalities occurred, including 3 urinary tract infections, 1 pneumonia, 1 wound infection, 5 ileus, 2 persistent chylous drainage, 3 urinary fistulas, and 3 (5% postoperative complications that required surgical intervention (2 hernias - one in the port site and one in the extraction incision, and 1 bowel obstruction. One case (1.7% was electively converted to open surgery due to a larger tumor that precluded proper posterior dissection. Two mortalities (3.3% occurred in this series, one early mortality due to uncontrolled upper gastrointestinal bleeding and one late mortality following massive pulmonary embolism. CONCLUSIONS: Laparoscopic radical cystectomy is a safe operation with morbidity and mortality rates comparable to the open surgery.

  14. Under-recognition of acral peeling skin syndrome: 59 new cases with 15 novel mutations.

    Science.gov (United States)

    Szczecinska, W; Nesteruk, D; Wertheim-Tysarowska, K; Greenblatt, D T; Baty, D; Browne, F; Liu, L; Ozoemena, L; Terron-Kwiatkowski, A; McGrath, J A; Mellerio, J E; Morton, J; Woźniak, K; Kowalewski, C; Has, C; Moss, C

    2014-11-01

    Acral peeling skin syndrome (APSS) is a rare skin fragility disorder usually caused by mutations in the transglutaminase 5 gene (TGM5). We investigated the mutation spectrum of APSS in the U.K., Germany and Poland. We identified 59 children with APSS from 52 families. The phenotype was readily recognizable, with some variation in severity both within and between families. Most cases had been misdiagnosed as the localized form of epidermolysis bullosa simplex (EBS-loc). Eighteen different TGM5 mutations were identified, 15 of which were novel. Eight mutations were unique to a single family, nine each occurred in two families, while the common p.Gly113Cys mutation linked to a second missense variant p.Thr109Met occurred in 47 of the 52 families and was homozygous in 28. Most patients were of nonconsanguineous white European origin. We propose that APSS is under-reported and widely misdiagnosed as EBS-loc, with significant counselling implications as APSS is autosomal recessive while EBS-loc is dominant. We recommend screening for TGM5 mutations when EBS-loc is suspected but not confirmed by mutations in KRT5 or KRT14. Our report trebles the number of known TGM5 mutations. It provides further evidence that p.Gly113Cys is a founder mutation in the European population. This is consistent with the striking ethnic distribution of APSS in U.K., where the majority of patients are of nonconsanguineous white European origin, in contrast to the pattern of other recessive skin disorders. © 2014 British Association of Dermatologists.

  15. Clinicoradiological study on 59 patients with pure motor hemiparesis due to corona radiata infarcts

    International Nuclear Information System (INIS)

    Nagaoka, Tetsuro; Kawabe, Kiyokazu; Ito, Hirono; Ikeda, Ken

    2009-01-01

    To evaluate the clinicoradiological findings of patients with small infarction at the level of the corona radiata, such patients were divided into three groups: Group A (facio-lingual weakness), Group B (arm-dominant weakness) and Group C (leg-dominant weakness). The anteroposterior position and maximum diameter of the radiata infarcts were assessed by axial T2-weighted imaging. In total, 59 consecutive patients (42 men and 17 women) were selected. The frequency of radiata infarct is 9.4% among cerebral infarct patients. The male/female ratio was 1.3. The mean age (SD) was 68.9 (9.5) years. The number of patients was 23 in Group A, 19 in Group B and 17 in Group C. Group B patients needed aid in their daily life, when compared to Group A and Group C. The cerebrovascular risk profiles demonstrated hypertension in 43 patients (72.9%), diabetes mellitus in 15 (25.4%), current smoking in 22 (37.3%), dyslipidemia in 16 (27.1%) and arterial fibrillation in 11 (18.6%). The clinical subtypes revealed 48 patients with lacunar infarct and 11 with cardiogenic emboli. The somatotopical distribution of motor fibers of Groups A to C was arranged in antero-posterior order. There were 24 patients with right lesions and 35 with left lesions. The size of the left infarcts was significantly smaller than that of the right infarcts. The clinical outcome of patients with arm-dominant weakness was relatively poor as compared to that of patients with dysarthria or leg-dominant weakness. The neuroradiological data suggest that left radiata infarct is smaller and more frequent than right infarct. (author)

  16. Clinicoradiological study on 59 patients with pure motor hemiparesis due to corona radiata infarcts

    Energy Technology Data Exchange (ETDEWEB)

    Nagaoka, Tetsuro; Kawabe, Kiyokazu; Ito, Hirono; Ikeda, Ken [Toho Univ., Omori Medical Center, Tokyo (Japan)

    2009-07-15

    To evaluate the clinicoradiological findings of patients with small infarction at the level of the corona radiata, such patients were divided into three groups: Group A (facio-lingual weakness), Group B (arm-dominant weakness) and Group C (leg-dominant weakness). The anteroposterior position and maximum diameter of the radiata infarcts were assessed by axial T2-weighted imaging. In total, 59 consecutive patients (42 men and 17 women) were selected. The frequency of radiata infarct is 9.4% among cerebral infarct patients. The male/female ratio was 1.3. The mean age (SD) was 68.9 (9.5) years. The number of patients was 23 in Group A, 19 in Group B and 17 in Group C. Group B patients needed aid in their daily life, when compared to Group A and Group C. The cerebrovascular risk profiles demonstrated hypertension in 43 patients (72.9%), diabetes mellitus in 15 (25.4%), current smoking in 22 (37.3%), dyslipidemia in 16 (27.1%) and arterial fibrillation in 11 (18.6%). The clinical subtypes revealed 48 patients with lacunar infarct and 11 with cardiogenic emboli. The somatotopical distribution of motor fibers of Groups A to C was arranged in antero-posterior order. There were 24 patients with right lesions and 35 with left lesions. The size of the left infarcts was significantly smaller than that of the right infarcts. The clinical outcome of patients with arm-dominant weakness was relatively poor as compared to that of patients with dysarthria or leg-dominant weakness. The neuroradiological data suggest that left radiata infarct is smaller and more frequent than right infarct. (author)

  17. C1q nephropathy and isolated CD59 deficiency manifesting as necrotizing crescentic glomerulonephritis: A rare association of two diseases

    Directory of Open Access Journals (Sweden)

    Ruchika Gupta

    2015-01-01

    Full Text Available C1q nephropathy is a recently described clinico-pathologic entity with a variable clinical presentation and pathology. Crescentic glomerulonephritis (GN has been reported in only two patients in the available literature. CD59 deficiency, along with lack of CD55, is responsible for paroxysmal nocturnal hemoglobinuria (PNH. Few cases of isolated CD59 deficiency have been described with PNH-like features. A middle-aged adult male presented with rapidly progressive renal failure. Serological investigations were negative. A renal biopsy revealed necrotizing crescentic GN with rupture of Bowman′s capsule. Immunofluorescence on the frozen sections showed dominant mesangial deposits of C1q along with IgM. Hematological work-up of the patient revealed isolated CD59 deficiency. Hence, a final diagnosis of C1q nephropathy and CD59 deficiency manifesting as crescentic GN and hemolytic anemia was made. The co-existence of two rare disorders, C1q nephropathy and CD59 deficiency, in a patient with necrotizing crescentic GN is described for the first time to the best of our knowledge. The pathogenetic link of these two entities with the clinical manifestation requires further study.

  18. Hydrology of area 59, northern Great Plains and Rocky Mountain coal provinces, Colorado and Wyoming

    Science.gov (United States)

    Gaggiani, Neville G.; Britton, Linda J.; Minges, Donald R.; Kilpatrick, F.A.; Parker, Randolph S.; Kircher, James E.

    1987-01-01

    Hydrologic information and analysis aid in decisions to lease federally owned coal and to prepare necessary Environmental Assessments and Impact Study reports. This need has become even more critical with the enactment of Public Law 95-87, the "Surface Mining Control and Reclamation Act of 1977." This act requires an appropriate regulatory agency to issue permits, based on the review of permit-application data to assess hydrologic impacts. This report, which partially fulfills this requirement, is one in a series of nationwide coal province reports that present information thematically, through the use of a brief text and accompanying maps, graphs, charts, or other illustrations for single hydrologic topics. The report broadly characterizes the hydrology of Area 59 in north-central Colorado and southeastern Wyoming.The report area, located within the South Platte River basin, covers a 16,000-square-mile area of diverse geology, topography, and climate. This diversity results in contrasting hydrologic characteristics.The South Platte River, the major stream in the area, and most of its tributaries originate in granitic mountains and flow into and through the sedimentary rocks of the Great Plains. Altitudes range from less than 5,000 feet to more than 14,000 feet above sea level. Precipitation in the mountains may exceed 40 inches annually, much of it during the winter, and produces deep snowpacks. Snowmelt during the spring and summer produces most streamflow. Transmountain diversion of water from the streams on the western slope of the mountains also adds to the streamflow. Precipitation in the plains is as little as 10 inches annually. Streams that originate in the plains are ephemeral.Streamflow quality is best in the mountains, where dissolved-solids concentrations are generally small. Concentrations increase in the plains as streams flow through sedimentary basins, and as urbanization and irrigation increase. The quality of some mountain streams is affected by

  19. Activity of vegetative insecticidal proteins Vip3Aa58 and Vip3Aa59 of Bacillus thuringiensis against lepidopteran pests.

    Science.gov (United States)

    Baranek, Jakub; Kaznowski, Adam; Konecka, Edyta; Naimov, Samir

    2015-09-01

    Vegetative insecticidal proteins (Vips) secreted by some isolates of Bacillus thuringiensis show activity against insects and are regarded as insecticides against pests. A number of B. thuringiensis strains harbouring vip3A genes were isolated from different sources and identified by using a PCR based approach. The isolates with the highest insecticidal activity were indicated in screening tests, and their vip genes were cloned and sequenced. The analysis revealed two polymorphic Vip protein forms, which were classified as Vip3Aa58 and Vip3Aa59. After expression of the vip genes, the proteins were isolated and characterized. The activity of both toxins was estimated against economically important lepidopteran pests of woodlands (Dendrolimus pini), orchards (Cydia pomonella) and field crops (Spodoptera exigua). Vip3Aa58 and Vip3Aa59 were highly toxic and their potency surpassed those of many Cry proteins used in commercial bioinsecticides. Vip3Aa59 revealed similar larvicidal activity as Vip3Aa58 against S. exigua and C. pomonella. Despite 98% similarity of amino acid sequences of both proteins, Vip3Aa59 was significantly more active against D. pini. Additionally the effect of proteolytic activation of Vip58Aa and Vip3Aa59 on toxicity of D. pini and S. exigua was studied. Both Vip3Aa proteins did not show any activity against Tenebrio molitor (Coleoptera) larvae. The results suggest that the Vip3Aa58 and Vip3Aa59 toxins might be useful for controlling populations of insect pests of crops and forests. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Production, purification, sequencing and activity spectra of mutacins D-123.1 and F-59.1

    Directory of Open Access Journals (Sweden)

    LaPointe Gisèle

    2011-04-01

    Full Text Available Abstract Background The increase in bacterial resistance to antibiotics impels the development of new anti-bacterial substances. Mutacins (bacteriocins are small antibacterial peptides produced by Streptococcus mutans showing activity against bacterial pathogens. The objective of the study was to produce and characterise additional mutacins in order to find new useful antibacterial substances. Results Mutacin F-59.1 was produced in liquid media by S. mutans 59.1 while production of mutacin D-123.1 by S. mutans 123.1 was obtained in semi-solid media. Mutacins were purified by hydrophobic chromatography. The amino acid sequences of the mutacins were obtained by Edman degradation and their molecular mass was determined by mass spectrometry. Mutacin F-59.1 consists of 25 amino acids, containing the YGNGV consensus sequence of pediocin-like bacteriocins with a molecular mass calculated at 2719 Da. Mutacin D-123.1 has an identical molecular mass (2364 Da with the same first 9 amino acids as mutacin I. Mutacins D-123.1 and F-59.1 have wide activity spectra inhibiting human and food-borne pathogens. The lantibiotic mutacin D-123.1 possesses a broader activity spectrum than mutacin F-59.1 against the bacterial strains tested. Conclusion Mutacin F-59.1 is the first pediocin-like bacteriocin identified and characterised that is produced by Streptococcus mutans. Mutacin D-123.1 appears to be identical to mutacin I previously identified in different strains of S. mutans.

  1. Tribological behavior of the kinetic sprayed Ni59Ti16Zr20Si2Sn3 bulk metallic glass

    International Nuclear Information System (INIS)

    Choi, Hanshin; Jo, Hyungho; An, Kyoungjun; Yoon, Sanghoon; Lee, Changhee

    2007-01-01

    Gas atomized amorphous Ni 59 Ti 16 Zr 20 Si 2 Sn 3 feedstock particles were fed into warm gas dynamics and they were successfully overlaid onto the mild steel substrate. Through the X-ray diffractometry and differential scanning calorimetry, it could be confirmed that thermally activated processes such as crystallization and in-flight particle oxidation were effectively suppressed during the modified kinetic spraying process. In order to evaluate the tribological behavior of the kinetic sprayed Ni 59 Ti 16 Zr 20 Si 2 Sn 3 BMG coating, a partially crystallized coating and a fully crystallized coating were prepared by isothermal heat treatments

  2. Severe imported malaria in an intensive care unit: a review of 59 cases

    Directory of Open Access Journals (Sweden)

    Santos Lurdes C

    2012-03-01

    Full Text Available Abstract Background In view of the close relationship of Portugal with African countries, particularly former Portuguese colonies, the diagnosis of malaria is not a rare thing. When a traveller returns ill from endemic areas, malaria should be the number one suspect. World Health Organization treatment guidelines recommend that adults with severe malaria should be admitted to an intensive care unit (ICU. Methods Severe cases of malaria in patients admitted to an ICU were reviewed retrospectively (1990-2011 and identification of variables associated with in-ICU mortality performed. Malaria prediction score (MPS, malaria score for adults (MSA, simplified acute physiology score (SAPSII and a score based on WHO's malaria severe criteria were applied. Statistical analysis was performed using StataV12. Results Fifty nine patients were included in the study, all but three were adults; 47 (79,6% were male; parasitaemia on admission, quantified in 48/59 (81.3% patients, was equal or greater than 2% in 47 of them (97.9%; the most common complications were thrombocytopaenia in 54 (91.5% patients, associated with disseminated intravascular coagulation (DIC in seven (11.8%, renal failure in 31 (52.5% patients, 18 of which (30.5% oliguric, shock in 29 (49.1% patients, liver dysfunction in 27 (45.7% patients, acidaemia in 23 (38.9% patients, cerebral dysfunction in 22 (37.2% patients, 11 of whom with unrousable coma, pulmonary oedema/ARDS in 22 (37.2% patients, hypoglycaemia in 18 (30.5% patients; 29 (49.1% patients presented five or more dysfunctions. The case fatality rate was 15.2%. Comparing the four scores, the SAPS II and the WHO score were the most sensitive to death prediction. In the univariate analysis, death was associated with the SAPS II score, cerebral malaria, acute renal and respiratory failure, DIC, spontaneous bleeding, acidosis and hypoglycaemia. Age, partial immunity to malaria, delay in malaria diagnosis and the level of parasitaemia were

  3. Final decommissioning of the former active handling Building A59 at UKAEA Winfrith

    International Nuclear Information System (INIS)

    Cornell, Rowland; Brown, Nick; Staples, Andy

    2006-01-01

    RWE NUKEM has been decommissioning the former active handling Building A59 at Winfrith since July 2000 for the site owners and nuclear site licence holders UKAEA, following a competitive tendering process. Following recent government changes the UK's Nuclear Decommissioning Authority has contracts with UKAEA for delivery of the site clean-up programme. Decommissioning work has centred upon two heavily shielded suites of caves originally used to carry out remote examination of irradiated nuclear fuel elements although other supporting facilities are also involved. Starting activity and contamination levels were extremely high in the two cave lines but decommissioning operations have steadily advanced and both facilities have now been decontaminated such that they are ready for demolition. The processes used to achieve this objective involved mainly standard off-the-shelf equipment but the work has demonstrated the importance of undertaking the task with the right tooling and lessons learnt will be described for the benefit of other operators. The essential challenge is always to achieve these objectives in a safe and cost-effective way whilst ensuring that the radiation exposure of the operators is kept as low as reasonably practicable (ALARP). This paper describes how the approach to cave line demolition had to be amended from the original plan owing to features of the original building design which provide structural support for the main fabric from the concrete cave line walls. As a result, the original plan to demolish the cave lines first could not be undertaken economically and the building itself will now be cleared, decontaminated and demolished ahead of these two major facilities. Considerable benefits have flowed from this decision and the paper will set out the advantages that have been gained, which may be of benefit to others carrying out similar tasks. Finally, the paper will explain how the achievement of cost-effective and safe solutions to all these

  4. Growth of congruently melting Ca0.59Sr0.41F2 crystals and study of their properties

    Science.gov (United States)

    Karimov, D. N.; Komar'kova, O. N.; Sorokin, N. I.; Bezhanov, V. A.; Chernov, S. P.; Popov, P. A.; Sobolev, B. P.

    2010-05-01

    Homogeneous crystals of Ca0.59Sr0.41F2 alloy (sp. gr., Fm bar 3 m, a = 0.56057 nm), corresponding to the point of minimum in the melting curve in the CaF2-SrF2 phase diagram, have been grown by the vertical Bridgman method. The optical, mechanical, electrical, and thermophysical properties of Ca0.59Sr0.41F2 and MF2 crystals ( M = Ca, Sr) have been studied and comparatively analyzed. Ca0.59Sr0.41F2 crystals are transparent in the range of 0.133-11.5 μm, have refractive index n D = 1.436, microhardness H μ = 2.63 ± 0.10 GPa, ion conductivity σ = 5 × 10-5 S/cm at 825 K, and thermal conductivity k = 4.0 W m-1 K-1 at 300 K. It is shown that the optical properties of Ca0.59Sr0.41F2 crystals are intermediate between those of CaF2 and SrF2, whereas their mechanical and electrical characteristics are better than the latter compounds.

  5. The Beautiful Brain: A Unit for Grades 5-9 with Further Explorations for Gifted and Talented.

    Science.gov (United States)

    Struve, Nancy

    The unit provides information on the study of the human brain for students in grades 5-9 with suggestions for extending the lessons for gifted and talented students. Learning activities are offered for ten lessons (sample subtopics in parentheses); introduction to the unit (student pretest and posttest); brain growth; medulla-oblongata-reptilian…

  6. 77 FR 9231 - Lock+ Hydro Friends Fund XXVIII; FFP Project 59, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-16

    ...+ Hydro Friends Fund XXVIII; FFP Project 59, LLC; Notice Announcing Preliminary Permit Drawing The... of the Commission, or her designee, will conduct a random drawing to determine the filing priority of... applications as provided in section 4.37 of its regulations.\\2\\ The priority established by this drawing will...

  7. Ferrous and hemoglobin-59Fe absorption from supplemented cow milk in infants with normal and depleted iron stores

    International Nuclear Information System (INIS)

    Heinrich, H.C.; Gabbe, E.E.; Whang, D.H.; Bender-Goetze, C.; Schaefer, K.H.; Hamburg Univ.

    1975-01-01

    Small amounts of milk do inhibit ferrous iron absorption from a 5 mg 59 Fe 2+ dose in 1- to 18-month-old infants. Only 50 ml of 2/3 cow milk reduced the absorption from 18 to 3.8% in infants with normal iron stores (inhibition index 0.21) and from 26 to 8.5% in [de

  8. 10-GHz 1.59-μm quantum dash passively mode-locked two-section lasers

    DEFF Research Database (Denmark)

    Dontabactouny, Madhoussoudhana; Rosenberg, C.; Semenova, Elizaveta

    2010-01-01

    This paper reports the fabrication and the characterisation of a 10 GHz two-section passively mode-locked quantum dash laser emitting at 1.59 μm. The potential of the device's mode-locking is investigated through an analytical model taking into account both the material parameters and the laser...

  9. On-Ball Doping of Fullerenes : The Electronic Structure of C59N Dimers from Experiment and Theory

    NARCIS (Netherlands)

    Pichler, Thomas; Knupfer, Martin; Golden, Mark S.; Haffner, Stefan; Friedlein, Rainer; Fink, Jörg; Andreoni, Wanda; Curioni, Alessandro; Keshavarz-K, Majid; Bellavia-Lund, Cheryl; Sastre, Angela; Hummelen, Jan-Cornelis; Wudl, Fred

    1997-01-01

    We present the first studies of the electronic structure of the heterofullerene (C59N)2 using electron energy-loss spectroscopy in transmission, photoemission spectroscopy, and density functional theory calculations. Both the C 1s excitation spectra and valence band photoemission show negligible

  10. [Assessment of the MF59-adjuvanted pandemic influenza A/H1N1 vaccine. Systematic review of literature].

    Science.gov (United States)

    Ruiz-Aragón, J; Grande Tejada, A M; Márquez-Peláez, S; Molina Linde, J M; Yang, R

    2013-10-01

    To assess the efficacy and safety of MF59-adjuvanted pandemic influenza A/H1N1 vaccine in children. A systematic review of the literature was performed after searching the MedLine and Embase electronic databases, and manual search in specialties journals, with MeSH terms and and free terms. Inclusion criteria were clinical trials with children vaccinated with MF59-adjuvanted influenza A/H1N1 vaccine, compared with other vaccines doses with/without MF59-adjuvanted. The immunogenicity and safety of the vaccine was recorded. The quality of the studies included was assessed by CASPe checklist. Four clinical trials with moderate quality were selected. The local and systemic adverse effects were rare and mild, with no differences between groups. Seroconversion and seroprotection levels were higher with MF59-adjuvanted vaccines. Antibody titres were also higher with the adjuvant vaccines. The adjuvant vaccine has a good efficacy and safety profile. The adverse effects that may occur are common and appear similarly in both vaccination groups. Copyright © 2012 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

  11. 17 CFR 1.59 - Activities of self-regulatory organization employees, governing board members, committee members...

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Activities of self-regulatory... COMMODITY EXCHANGE ACT Miscellaneous § 1.59 Activities of self-regulatory organization employees, governing...) Self-regulatory organization means “self-regulatory organization,” as defined in Commission regulation...

  12. Role of gene 59 of bacteriophage T4 in repair of uv-irradiated and alkylated DNA in vivo

    International Nuclear Information System (INIS)

    Wu, R.; Wu, J.L.; Yeh, Y.C.

    1975-01-01

    Nonsense mutants in gene 59 (amC5, am HL628) were used to study the role of this gene in the repair of uv-damaged and alkylated DNA of bacteriophage T4 in vivo. The higher sensitivity to uv irradiation and alkylation of gene 59 mutants after exposure to these agents was established by a comparison of the survival fractions with wild type. Zonal centrifugal analysis of both parental and nascent mutant intracellular DNA molecules after uv irradiation showed that immediately after exposure the size of single-stranded DNA fragments was the same as the wild-type intracellular DNA. However, the capability of rejoining fragmented intracellular DNA was greatly reduced in the mutant. In contrast, the wild-type-infected cells under the same condition resumed DNA replication and repaired its DNA to normal size. Methyl methanesulfonate induced more randomly fragmented intracellular DNA, when compared to uv irradiation. The rate of rejoining under these conditions as judged from their sedimentation profiles was also greatly reduced in mutant-infected cells. Further evidence is presented that uv repair is not a simple consequence of arrested DNA replication, which is a phenotype of the mutant when infected in a nonpermissive host, Escherichia coli B(su - ), but rather that the DNA repair function of gene 59 is independent of the replication function. These and other data presented indicate that a product(s) of gene 59 is essential for both repair of uv lesions and repair of alkylation damage of DNA in vivo. It is suggested that gene 59 may have two functions during viral development: DNA replication and replication repair of DNA molecules

  13. Identification of a new 6-bromo-5,9-eicosadienoic acid from the anemone Condylactis gigantea and the zoanthid Palythoa caribaeorum.

    Science.gov (United States)

    Carballeira, N M; Reyes, M

    1995-11-01

    A new brominated fatty acid, 6-bromo-5,9-eicosadienoic acid [1] was identified in the phospholipids (mainly phosphatidylethanolamine) of the anemone Condylactis gigantea and the zoanthid Palythoa caribaeorum. The delta 5,9 fatty acids, 5,9-octadecadienoic acid, 5,9-eicosadienoic acid, 5,9-docosadienoic acid, and 5,9-tetracosadienoic acid, were also identified in both organisms. Structural elucidation was accomplished by spectroscopic and chemical means. Our results further corroborate that delta 5,9 phospholipid fatty acids are not unique to sponges, as recognized previously, but can be found in other marine invertebrates such as anemones and zoanthids. An improved procedure for the synthesis of picolinyl esters is also described.

  14. Prevalence of anemia in children 6-59 months old in the state of Pernambuco, Brazil Prevalencia de la anemia en niños de 6 a 59 meses en el estado de Pernambuco, Brasil

    Directory of Open Access Journals (Sweden)

    Mônica M. Osório

    2001-08-01

    Full Text Available Objective. To determine the prevalence of anemia in children 6-59 months old in Pernambuco, a state in northeastern Brazil, so as to help guide health and nutrition policies there. Methods. In 1997 a representative sample of 777 young children had their hemoglobin concentration measured. The sampling process was in three stages. First, 18 municipalities were randomly selected to represent the state and its three geographic areas (metropolitan region of Recife, urban interior, and rural interior. Next, using census lists, 45 census sectors were randomly chosen. Finally, 777 children aged 6-59 months old were selected. Blood was collected by venipuncture, and hemoglobin was measured with a portable hemoglobinometer. In the analysis, prevalence was weighted to reflect the census age distribution. Results. The prevalence of anemia among children 6-59 months old was 40.9% for the state as a whole. Prevalence in the metropolitan region of Recife was 39.6%, and it was 35.9% in the urban interior. The rural interior had the highest prevalence, 51.4%. Prevalence was twice as high in children aged 6-23 months as among those 24-59 months old, 61.8% vs. 31.0% (chi² = 77.9, P Objetivos. Determinar la prevalencia de la anemia en niños de 6 a 59 meses en Pernambuco, un estado del nordeste de Brasil, con el fin de ayudar a establecer las políticas de salud y nutrición. Métodos. En 1997 se determinaron las concentraciones de hemoglobina en una muestra representativa de 777 niños. El proceso de muestreo se realizó en tres fases. Primero se seleccionaron aleatoriamente 18 municipios representativos del estado y de sus tres zonas geográficas (la región metropolitana de Recife, el interior urbano y el interior rural. A continuación, utilizando las listas del censo, se seleccionaron aleatoriamente 45 sectores censales. Finalmente, se seleccionaron 777 niños de 6 a 59 meses de edad. La sangre se recogió por punción venosa y la hemoglobina se midió con un

  15. Amotosalen: Allogeneic Cellular Immunotherapies system, INTERCEPT Plasma System, INTERCEPT Platelet System, S 59.

    Science.gov (United States)

    2003-01-01

    Adis CommentsCerus Corporation is developing a variety of pathogen-inactivation systems, based on its Helinx technology. Three of the systems include amotosalen [S 59] as the inactivation compound. Amotosalen is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens. The systems that utilise amotosalen are called the INTERCEPT Platelet System, the INTERCEPT Plasma System and the Allogeneic Cellular Immunotherapies (ACIT) system. The INTERCEPT Platelet System and INTERCEPT Plasma System are two of the systems that make up Cerus' INTERCEPT Blood Systems. The other system is the INTERCEPT Red Blood Cell System, which contains S 303 as the inactivation compound rather than amotosalen. Cerus' Helinx technology is able to prevent replication of DNA or RNA that is present in pathogens but not in the blood components being treated (e.g. platelets and plasma). When added to the blood components, the inactivation agent (in this case amotosalen) crosses the membrane or cell wall of the pathogen. When activated by light, amotosalen binds to the nucleic acid of the pathogen and prevents replication. This process prevents infection. INTERCEPT Platelet System: Cerus developed its INTERCEPT Platelet System, in collaboration with Baxter Healthcare, for use in blood centres. Platelets are an essential component of the coagulation process and may be required by patients undergoing surgery, cancer chemotherapy, transplantation or with bleeding disorders. The system is made up of an illuminator device, a compound absorption device and a processing kit containing amotosalen. In October 2002, the two companies announced that CE Mark approval had been received for the illuminator device for the INTERCEPT trade mark Blood System. Application of this technology to platelets is the first to be approved. As it is a new technology, the system is currently undergoing process validation in accordance with European Blood Bank GMP requirements. This

  16. Adrenocortical scintigraphy with {sup 131}I-6-beta-iodomethyl-norcholesterol (NP 59) in bilateral adrenocortical carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz Hernandez, G.; Pallares, F.J.C.; Avila y Avalos, C.R. de [Hospital Clinic Universitari de Valencia (Spain). Servei de Medicina Nuclear; Bartual, A.R.; Rodrigo, S.T.; Ampudia-Blasco, F.J. [Hospital Clinic Universitari de Valencia (Spain). Servei d`Endocrinologia

    1998-06-01

    A case of a 49-year-old man suffering from bilateral adrenocortical carcinoma with local and secondary rapid progression is reported. The results of adrenocortical scintigraphy (NP 59) and histological findings allowed the diagnosis. This case report and a literature review showed the importance of using adrenocortical scintigraphy as a complementary imaging procedure of CT or MR images. (orig.) [Deutsch] Es wird ueber einen 49jaehrigen Mann berichtet, der an einem beidseitigen Nebennierenrinden-Karzinom mit schneller lokaler und sekundaerer Progression leidet. Die Ergebnisse der Nebennierenrinden-Szintigraphie (NP 59) und Histologie ermoeglichten die Diagnose: Dieser Fallbericht und ein Literaturueberblick zeigen die Bedeutung der Nebennierenrinden-Szintigraphie als ein zusaetzliches bildgebendes Verfahren neben CT und NMR. (orig.)

  17. Effect of excess supply of heavy metals on the absorption and translocation of iron (/sup 59/Fe) in barley

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, C P; Bisht, S S; Agarwala, S C [Lucknow Univ. (India). Dept. of Botany

    1978-03-01

    The effects of an excess supply of manganese, copper, zinc, cobalt, and nickel on the absorption and translocation of iron tagged with /sup 59/Fe were xamined in 15 days old barley seedlings raised in solution culture. Excess heavy metal treatments and /sup 59/Fe were administered in three different ways: (i) both excess heavy metals and iron supplied through roots- Series A; (ii) excess heavy metal supplied as foliar spray and iron through roots- Series B; and (iii) excess heavy metal supplied through roots and iron as foliar spray-Series C. Results obtained revealed that excess concentrations of manganese, zinc, cobalt, and a to a lesser extent copper interfered with the absorption of iron from the rooting medium, but excess nickel enhanced the absorption and translocation of iron. Thus, unlike other metals, a toxic supply of nickel does not induce iron deficiency.

  18. Upper limits on the 21 cm power spectrum at z = 5.9 from quasar absorption line spectroscopy

    Science.gov (United States)

    Pober, Jonathan C.; Greig, Bradley; Mesinger, Andrei

    2016-11-01

    We present upper limits on the 21 cm power spectrum at z = 5.9 calculated from the model-independent limit on the neutral fraction of the intergalactic medium of x_{H I} chain Monte Carlo Epoch of Reionization analysis code, we explore the probability distribution of 21 cm power spectra consistent with this constraint on the neutral fraction. We present 99 per cent confidence upper limits of Δ2(k) limit dependent on the sampled k mode. This limit can be used as a null test for 21 cm experiments: a detection of power at z = 5.9 in excess of this value is highly suggestive of residual foreground contamination or other systematic errors affecting the analysis.

  19. Correlation of scintigraphy with short interval autopsy in malignant focal liver disease. A study of 59 cases

    International Nuclear Information System (INIS)

    Ruiter, D.J.; Byck, W.; Pauwels, E.K.J.; Taconis, W.K.; Spaander, P.J.

    1977-01-01

    The accuracy of scintigraphy in focal liver disease was evaluated by comparing the scintigraphic and autopsy findings in 59 patients. The interval between scintigraphy and autopsy was not more than a few weeks. The overall agreement rate was 49 in 59 (83 percent), with four out of 26 (15 percent) false positive and six out of 33 (18 percent) false negative reports. Defects smaller than 2 1 / 2 cm were the principal source of false negative reports. The accuracy of interpretation in cases with liver weights up to 2000 g was significantly (P less than 0.025) lower than for higher weights. Detection of a single focal lesion by scintigraphy was found to be unreliable (only two out of 13 correct). Estimation of spleen weights by scintigraphy was disappointing. Liver weight estimates were somewhat more satisfactory

  20. Supplemental site inspection for Air Force Plant 59, Johnson City, New York, Volume 3: Appendices F-Q

    Energy Technology Data Exchange (ETDEWEB)

    Nashold, B.; Rosenblatt, D.; Hau, J. [and others

    1995-08-01

    This summary describes a Supplemental Site Inspection (SSI) conducted by Argonne National Laboratory (ANL) at Air Force Plant 59 (AFP 59) in Johnson City, New York. All required data pertaining to this project were entered by ANL into the Air Force-wide Installation Restoration Program Information System (IRPIMS) computer format and submitted to an appropriate authority. The work was sponsored by the United States Air Force as part of its Installation Restoration Program (IRP). Previous studies had revealed the presence of contaminants at the site and identified several potential contaminant sources. Argonne`s study was conducted to answer questions raised by earlier investigations. This volume consists of appendices F-Q, which contain the analytical data from the site characterization.

  1. Increased immunogenicity of the MF59-adjuvanted influenza vaccine compared to a conventional subunit vaccine in elderly subjects

    International Nuclear Information System (INIS)

    Gasparini, R.; Pozzi, T.; Montomoli, E.; Fragapane, E.; Senatore, F.; Minutello, M.; Podda, A.

    2001-01-01

    Three-hundred and eight outpatient elderly subjects (≥ 65 years) were randomly assigned to receive the MF59-adjuvanted influenza vaccine (FLUAD; n = 204) or a conventional subunit influenza vaccine (AGRIPPAL S1; n = 104) in order to compare the safety and immunogenicity of the two vaccines. Although mild pain at the injection site was reported more frequently by subjects immunised with the adjuvanted vaccine, both vaccines were shown to be safe and well tolerated. The adjuvanted vaccine was more immunogenic as indicated by higher post-immunisation geometric mean titres (GMTs) and by higher proportions of subjects with post-immunisation ≥ four fold increases of antibody titres or subjects with ≥ 1/160 post-immunisation HI titres. These differences, statistically significant for all three strains after immunisation, indicated that, by addition of the MF59 adjuvant emulsion, conventional subunit influenza antigens acquire an enhanced immunogenicity without any clinically significant increase of their reactogenicity

  2. Satelite structure in 59Co NMR spectrum of magnetically ordered Dysub(1-x)Ysub(x)Co2 intermetallic compound

    International Nuclear Information System (INIS)

    Yoshimura, Kazuyoshi; Hirosawa, Satoshi; Nakamura, Yoji

    1984-01-01

    The magnetic environment effect of cobalt in Dysub(1-x)Ysub(x)Co 2 has been studied by means of bulk magnetization and 59 Co spin-echo NMR measurements at 4.2K. Clearly resolved satellite structures of the NMR spectra have been observed. The hyperfine field distributions of 59 Co are decomposed into contributions of Co atoms in various nearest neighbor configurations of rare earth atoms. In this analysis the dipole field due to nearest neighbor rare earth moments plays an important role. The result indicates that the magnetic moment of Co in the RCo 2 cubic Laves phase pseudobinary compounds is quite sensitive to the nearest neighbor rare earth environment. (author)

  3. The terminal complement complex is generated in chronic leg ulcers in the absence of protectin (CD59)

    DEFF Research Database (Denmark)

    Balslev, E; Thomsen, H K; Danielsen, L

    1999-01-01

    Loss of membrane complement regulators accompanied by complement activation is suggested to be involved in the pathophysiological processes leading to tissue damage in myocardial ischaemia. In the present study we have investigated whether the same phenomenon may occur in ischaemic and/or venous...... results suggest that loss of CD59 may enhance deposition of TCC and that complement-dependent inflammation may be an important factor in the tissue-damaging processes seen in chronic leg ulcers....

  4. Relationship towards Engineering, Quality Assurance and 10CFR50.59 in the Design Change Process at the Krsko NPP

    International Nuclear Information System (INIS)

    Basic, I.; Krajnc, B.

    1998-01-01

    The paper discusses the relationship between the Krsko NPP design change engineering practice, quality assurance and the USA Nuclear Regulatory Commission 10 Code Federal Rule 50.59 (10CFR50.59). Together these controls ensure that plant design bases are maintained and yield a safe design. The 10CFR50.59 has been applied in Krsko NPP plant specific procedure entitled ESP-2.303 ''Authorization of Changes, Tests and Experiments'' (Safety Evaluation Screening) since 1994. All proposed changes requiring Safety Evaluations are being submitted to the SNSA (Slovenian Nuclear Safety Administration). If the proposed change is constituting an ''Unreviewed Safety Question'' the formal licensing procedure shall be completed before design change can be implemented otherwise the proposed design change is rejected. The procedure(ESP-2.303) provides the methodology to be followed in determining if a proposed activity involves an unreviewed safety question. An ''Unreviewed Safety Question'' is essentially the same as defined in 10CFR50.59(a)(2): ''A proposed change, test or experiment shall be deemed to involve an unreviewed safety question (1) if the probability of occurrence or consequences of an accident or malfunction of equipment important to safety previously evaluated in the (updated) safety analysis report may be increased; or (2) if a possibility for an accident or malfunction of a different type than any evaluated previously in the (updated) safety analysis report may be created; or (3) if the margin of safety as defined in the basis for any technical specification is reduced.'' This paper discusses the Following Krsko NPP Safety Evaluation aspects: 1. Defense in Depth Design Philosophy 2. Methodology 3. Definitions and Applicability of Terms 4. Evaluation Process Guidance and Documentation Process 5. Krsko NPP Lessons Learned. (author)

  5. Correction to: Cyberpsychol Behav Soc Netw 2015;18(2);59-71 DOI: 10.1089/cyber.2014.0343.

    Science.gov (United States)

    2015-11-01

    In the February 2015 issue of Cyberpsychology, Behavior, and Social Networking (vol. 18, no. 2, pp. 59–71), the article "Association Between Pornography Use and Sexual Risk Behaviors in Adult Consumers: A Systematic Review," by Emily L. Harkness et al., the second author's name was displayed as "Barbara M. Mullan;" however, the middle initial is incorrect. The authors wish to apologize for the error and Dr. Mullan would like to be cited without a middle initial simply as "B Mullan."

  6. Effect of radioactive iron /sup 59/Fe on the embryogeny of sea-trout (Salmo trutta L. )

    Energy Technology Data Exchange (ETDEWEB)

    Dabrowski, K; Tucholski, S; Czarnocki, J

    1975-01-01

    Accumulation and diffusion of /sup 59/Fe in the eggs of Salmo trutta L. were observed under laboratory conditions. The dynamics of iron budget in the egg with developing embryo were determined. Differences were found in the accumulation and elimination of iron depending on the stage of the embryos development in the eggs at the time when they were put into the radionuclide solution and on the strength of its concentration.

  7. [Evaluation of Articles 33 and 59, of the Code of Deontology of Doctors in Catalonia (2005), judicially annulled].

    Science.gov (United States)

    Collazo Chao, Eliseo

    2009-01-01

    At the end of the year 2004, the Autonomous Conseil of the Medical School in Catalonia (Spain) approved its Deontology Code. The articles 33 and 59 were then judicially resorted by more than one hundred doctors in Catalonia; nowadays those articles themselves have been annulled by judicial sentence. This research aims to accomplish a valuation ethical and deontological of the annulled articles, according to the statutes.

  8. Use of the Derriford Appearance Scale 59 to assess patient-reported outcomes in secondary cleft surgery.

    Science.gov (United States)

    Ricketts, Sophie; Regev, Eran; Antonyshyn, Oleh M; Kiss, Alex; Fialkov, Jeffrey A

    2016-01-01

    Secondary rhinoplasty, one of the final procedures in addressing the stigma of the cleft lip and palate (CLP), has both functional and aesthetic objectives. The way in which physicians evaluate outcomes in surgery concerning aesthetics is changing. Well-designed patient-reported outcome measures to assess health-related quality of life improvements attributable to surgery are increasingly being used. The Derriford Appearance Scale 59 (DAS-59) is currently the only available validated patient-reported outcome measure that assesses concern about physical appearance. Twenty patients with CLP presenting between May 2009 and May 2013 for secondary rhinoplasty to Sunnybrook Health Sciences Centre (Toronto, Ontario) were recruited. DAS-59 measures were administered both preoperatively and at least six months after surgery. Pre- and postoperative measures were scored and compared. Item-by-item analysis of the measure was also performed. Total scores for this CLP group indicated greater concern about appearance than the general population. Across all subscales of the measure, there was a reduction in scores after secondary rhinoplasty suggesting less patient concern with appearance and a positive effect of surgery on patient quality of life. Item-by-item analysis suggested relatively few items in the measure were driving overall change in total scores. Comparison of pre- and postoperative scores with the DAS-59 in secondary cleft rhinoplasty suggests there is less concern with appearance after surgery. However, a small number of items within this generic scale contributing to this difference may suggest the need for a more patient specific measure for assessment of surgical outcomes in the cleft population.

  9. Hypermethylation of TRIM59 and KLF14 Influences Cell Death Signaling in Familial Alzheimer’s Disease

    Directory of Open Access Journals (Sweden)

    Michalina Wezyk

    2018-01-01

    Full Text Available Epigenetic mechanisms play an important role in the development and progression of various neurodegenerative diseases. Abnormal methylation of numerous genes responsible for regulation of transcription, DNA replication, and apoptosis has been linked to Alzheimer’s disease (AD pathology. We have recently performed whole transcriptome profiling of familial early-onset Alzheimer’s disease (fEOAD patient-derived fibroblasts. On this basis, we demonstrated a strong dysregulation of cell cycle checkpoints and DNA damage response (DDR in both fibroblasts and reprogrammed neurons. Here, we show that the aging-correlated hypermethylation of KLF14 and TRIM59 genes associates with abnormalities in DNA repair and cell cycle control in fEOAD. Based on the resulting transcriptome networks, we found that the hypermethylation of KLF14 might be associated with epigenetic regulation of the chromatin organization and mRNA processing followed by hypermethylation of TRIM59 likely associated with the G2/M cell cycle phase and p53 role in DNA repair with BRCA1 protein as the key player. We propose that the hypermethylation of KLF14 could constitute a superior epigenetic mechanism for TRIM59 hypermethylation. The methylation status of both genes affects genome stability and might contribute to proapoptotic signaling in AD. Since this study combines data obtained from various tissues from AD patients, it reinforces the view that the genetic methylation status in the blood may be a valuable predictor of molecular processes occurring in affected tissues. Further research is necessary to define a detailed role of TRIM59 and KLF4 in neurodegeneration of neurons.

  10. Effect of iodoacetic acid on 59Fe uptake and aconitase aivity during sporulation of Bacillus cereus T

    International Nuclear Information System (INIS)

    Twari, B.K.; Sharma, D.

    1975-01-01

    Iodoacetic acid (IAA), a well known inhibitor of glycolysis, inhibited sporulation of B. cereus T when added to the culture just prior to the transition stage at 2-2.5 hr. In the inhibited culture, no considerable aconitase activity and 59 Fe uptake were observed. Time studies with IAA in modified G-medium had shown that whenever it was added it prevented further glycolysis of glucose. Addition of IAA at zero hr had no effect on aconitase activity and 59 Fe uptake whether glucose was present or absent from the medium. IAA added at rising pH at 3 hr. i.e. after transition period had no effect on the pH characteristics and sporulation of the organism. IAA seems to inhibit the induction of metal transport system. There exists a considerable correlation between aconitase activity and 59 Fe uptake during growth and sporulation of B. cereus T in modified G-medium in the presence and absence of glucose. (author)

  11. EFOMP policy statement 16: The role and competences of medical physicists and medical physics experts under 2013/59/EURATOM.

    Science.gov (United States)

    Caruana, Carmel J; Tsapaki, Virginia; Damilakis, John; Brambilla, Marco; Martín, Guadalupe Martín; Dimov, Asen; Bosmans, Hilde; Egan, Gillian; Bacher, Klaus; McClean, Brendan

    2018-04-01

    On 5 December 2013 the European Council promulgated Directive 2013/59/EURATOM. This Directive is important for Medical Physicists and Medical Physics Experts as it puts the profession on solid foundations and describes it more comprehensively. Much commentary regarding the role and competences has been developed in the context of the European Commission project "European Guidelines on the Medical Physics Expert" published as Radiation Protection Report RP174. The guidelines elaborate on the role and responsibilities under 2013/59/EURATOM in terms of a mission statement and competence profile in the specialty areas of Medical Physics relating to medical radiological services, namely Diagnostic and Interventional Radiology, Radiation Oncology and Nuclear Medicine. The present policy statement summarises the provisions of Directive 2013/59/EURATOM regarding the role and competences, reiterates the results of the European Guidelines on the Medical Physics Expert document relating to role and competences of the profession and provides additional commentary regarding further issues arising following the publication of the RP174 guidelines. Copyright © 2018. Published by Elsevier Ltd.

  12. Normal iron absorption determined by means of whole body counting and red cell incorporation of 59Fe

    International Nuclear Information System (INIS)

    Larsen, L.; Milman, N.

    1977-01-01

    Gastrointestinal iron absorption was measured in 27 normal subjects (19 females and 8 males) by means of whole body counting. Whole body retention 14 days after oral administration of 10μCi 59 Fe together with a carrier dose of 9.9 mg Fe 2+ (as sulphate), was used as an expression of absorption. The percentage incorporation in the total erythrocyte mass of administered 59 Fe (erythrocyte incorporation) and of absorbed 59 Fe (red cell utilization) was also estimated. Geometric mean iron absorption was 8.3+-2.1 (SD% in females, 9.1+-2.2 % in males and 8.5+-2.1 % in the entire series. The difference between males and females was not significant. Erythrocyte incorporation was 7.7+-2.2 (SD) % (geometric mean) in the entire series and the correlation between iron absorption and erythrocyte incorporation was highly significant (r = 0.96,P < 0.001). Red cell utilization averaged 92.9 +- 4.0 (SEM)% (arithmetic mean) in the entire series. (author)

  13. Haemorrhage of gross domestic product from disability-adjusted-life-years among 15-59 year olds in Kenya

    Directory of Open Access Journals (Sweden)

    Joses Muthuri Kirigia

    2018-03-01

    Full Text Available Background: This article estimates non-health gross domestic product (GDP losses associated with Disability-Adjusted Life Years (DALY lost among 15-59 year olds (most productive age bracket in Kenya in 2015. Methods: This study employs the lost output or human capital approach (HCA to convert the DALYs lost from all causes into their monetary equivalents. The magnitude economic haemorrhage from each disease was obtained by multiplying the per capita non-health GDP in International Dollars by the total number of DALYs lost in a specific age group (15-29 years, 30-49 years, 50-59 years. Per capita non-health GDP equals per capita GDP minus total health expenditure in 2015. Data on DALYs and per capita total health expenditure were obtained from the World Health Organization and per capita GDP data was from IMF databases. Results: Kenya lost 9,405,184 DALYs among 15-59 years olds in 2015. That DALY loss caused a haemorrhage in GDP of Int$ 29,788,392,419. Approximately 48.6% of the GDP haemorrhage resulted from communicable diseases and nutritional conditions, 37.4% from non-communicable diseases, and 14.0% from injuries. Conclusion: There is need to augment domestic and external investments into national health systems and other systems that meet basic needs (education, food, water, sanitation, shelter to reduce disease burden. Key words: Non-health GDP, economic haemorrhage, disability-adjusted life year (DALY

  14. AMRI-59 has a role of radiosensitizer via enhancement of γ-ionizing radiation-induced apoptotic cell death

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Wan Gi; Cho, Jeong Hyun; Kim, Ju Yeon; Hwang, Sang Gu; Um, Hong Duck; Park, Jong Kuk [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    Recent in vitro studies have suggested that may increase the invasiveness of some cancer cells (e.g., glioma, hepatocellular carcinoma, and pancreatic cancer cells) by stimulating several intracellular signaling pathways and in vivo studies have found that radiotherapy of primary tumor sites may promote metastasis. Thus, in addition to having therapeutic effects, IR might promote the malignant traits of surviving cancer cells. The existing efforts to develop radiosensitizing agents have focused on overcoming radioresistance and reducing damage to normal tissues. Recently, concepts of personalized- or precision medicine are developed due to advancement of mega data technique, which provide new targets to develop new anti-cancer drugs. In this study, we sought to identify the radiosensitizer effect of AMRI-59 in vitro and in vivo., which is recently developed specific inhibitor of peroxiredoxin (Prx) I. AMRI-59 enhanced radiation-induced cell death and its mean calculated dose enhancement ratio was 1.26. We also found combination of AMRI-59 and IR In a xenograft assay, the combined PHCM and radiation group showed 14.3 days of growth delay versus the control in terms of tumor growth. The enhancement factor of this combined treatment was determined to be 2.03.

  15. Daya Bunuh Hand Sanitizer Berbahan Aktif Alkohol 59% dalam Kemasan Setelah Penggunaan Berulang terhadap Angka Lempeng Total (ALT

    Directory of Open Access Journals (Sweden)

    Isnaeni Walidah

    2014-03-01

    Full Text Available Kebersihan merupakan tahap awal untuk menjaga pola hidup sehat dan terhindar dari penyakit. Pencegahan penyebaran penyakit salah satunya adalah dengan mencuci tangan menggunakan antiseptik hand sanitizer.  Hand sanitizer berbahan aktif alkohol 40 – 80%  mampu menghambat pertumbuhan bakteri. Tetapi pemakaian hand  sanitizer yang tidak langsung habis akan mempengaruhi kualitas hand sanitizer Penggunaan berulang hand sanitizer akan mempengaruhi kemampuan bahan aktif dalam membunuh kuman karena alkohol sebagai bahan aktif pada hand sanitizer memiliki sifat yang mudah menguap. Tujuan penelitian untuk mengetahui daya bunuh hand sanitizer berbahan aktif alkohol 59% dalam kemasan setelah penggunaan berulang terhadap angka lempeng total. Metode  penelitian analitik observasional, menggunakan 10 responden yang diuji angka lempeng total pada tangan setelah penggunaan berulang hand sanitizer dari volume 50 ml sampai dengan ± 25 ml dan dari volume ± 25 ml sampai dengan ± 12,5 ml. Hasil penelitian menunjukkan daya bunuh hand sanitizer berbahan aktif alkohol 59% dalam kemasan setelah penggunaan berulang dari volume 50 ml sampai volume ± 25 ml sebesar  21,38%. Sedangkan daya bunuh hand sanitizer pada penggunaan berulang  hand sanitizer dari volume ± 25 ml sampai dengan volume ± 12,5 ml sebesar 15,83%. Ada pengaruh penggunaan berulang hand sanitizer berbahan aktif alkohol 59% dalam kemasan terhadap jumlah angka lempeng total

  16. Adherence to oral rehydration therapy among in-patient children aged 1-59 months with some or no dehydration.

    Science.gov (United States)

    Migowa, A N; Gatinu, B; Nduati, R W

    2010-04-01

    To determine adherence to oral rehydration solution (ORS) among in-patients aged 1-59 months suffering from gastroenteritis and having some dehydration (SD) or no dehydration (ND) in two rural hospitals in Kenya. Children aged 1-59 months suffering from acute gastroenteritis with (SD) or (ND) were enrolled into the study, examined and medical records reviewed. On the second and third day of follow up, children were re-examined to ascertain hydration status and care-takers interviewed. Ninety-nine children were enrolled. Forty-five (75%) of the 60 children with SD received a correct prescription for ORS but only 12 (20%) received the correct amount. Among the 39 children with ND, 23 (59%) received a correct prescription for ORS, however only 16 (41%) received the correct amount. On the 3rd day, 9 (15%) of the 60 children with SD at baseline and 2 (5%) of the 39 with ND were classified as having SD. Four in five children with SD and 6 in 10 children with ND fail to receive the correct amounts of ORS.

  17. Assessment of Alveolar Bone Status in Middle Aged Chinese (40-59 Years) with Chronic Periodontitis--Using CBCT.

    Science.gov (United States)

    Zhao, Haijiao; Li, Chen; Lin, Li; Pan, Yaping; Wang, Hongyan; Zhao, Jian; Tan, Lisi; Pan, Chunling; Song, Jia; Zhang, Dongmei

    2015-01-01

    This study used con-beam computed tomography (CBCT) to investigate the prevalence and severity of alveolar bone loss in middle-aged (40-59 years) Chinese with chronic periodontitis. The study group comprised 145 dentate individuals aged 40 to 59 years residing in China who suffered from chronic periodontitis. CBCT and the application of NNT software were used to examine the level and location of alveolar bone loss. The study revealed that 40-59 year old patients with chronic periodontitis had severe bone loss. At 5,286 sites (34.7%), alveolar bone loss was mild; severe alveolar bone loss was found at 5,978 sites (39.2%). A comparison of bone loss in different jaws revealed that the area with the highest degree of bone loss was on the lingual side of the maxillary molar (56.3 ± 7.2%), and that the area with the lowest degree was primarily on the lingual side of the mandibular canine (27.5 ± 6.3%). There was a lower degree of alveolar bone loss in males than females. Differences were observed when comparing the incidence of bone loss between males and females (P chronic periodontitis, the highest degrees of bone loss in the incisors, premolars, and molars were on the lingual side, mesial side and lingual side, respectively. Menopause in females and smoking may affect the level of bone loss.

  18. PREVALENSI HIPERTENSI PADA MASYARAKAT USIA 18-59 TAHUN DI WILAYAH KERJAPUSKESMAS TAMPAKSIRING I KABUPATEN GIANYAR BALI TAHUN 2013

    Directory of Open Access Journals (Sweden)

    Gusti Agung Bagus Viki Dwipayana

    2016-05-01

    Full Text Available THE DISTRIBUTION OF RISK FACTORS AND HYPERTENSION PREVALENCE TOWARDS 18-59 YEARS SOCIETY IN WORKING AREA OF UPT PUSKESMAS TAMPAKSIRING I IN NOVEMBER 2013 Background: Hypertension is a cardiovascular disorder that is estimated to cause approximately 13% of total deaths worldwide. The disorder is associated with a variety of risk factors, i.e risk factors that can not be modified as well as the risk factors that can be modified. From the reports of Puskesmas Tampaksiring I in 2012, hypertension was in top ten disease and the prevalence is increasing every year. At the beginning of the survey, 30 respondents were selected randomly, and found the prevalence of hypertension is quite high at 40%, compared to the prevalence in the Gianyar regency of 28.2%. Based on this, the authors conducted a study to determine the prevalence and risk factors distribution of hypertension on community aged 18-59 years in the working area of UPT Puskesmas Tampaksiring I. Methods: The study was conducted in the working area of Puskesmas Tampaksiring I, District of Tampaksiring, Gianyar, in November 2013. This study is a cross-sectional descriptive study with a total sample of 92 respondents who are the people in the working area UPT Puskesmas Tampaksiring I was 18-59 years. Data were obtained through a questionnaire which consisted of a number of questions as well as height and weight measurements were conducted by researcher. Results and Suggestions: The results showed that the prevalence of hypertension in the population aged 18-59 years in Puskesmas Tampaksiring I of 41.3% (CI 31.79 to 51.51. Hypertension more experienced by males (47.8%, age group 54-59 years old (65.6%, had a family history of hypertension (55.6%, never smoked (55.6%, the group that never consume alcohol (42.9%, coffee consumption (47.4%, a group that has a high stress level (100%, the group with mild physical activity (44.2%, and the obese group (64.9 %. Given the high prevalence of hypertension

  19. Relative Contribution of Cellular Complement Inhibitors CD59, CD46, and CD55 to Parainfluenza Virus 5 Inhibition of Complement-Mediated Neutralization

    Directory of Open Access Journals (Sweden)

    Yujia Li

    2018-04-01

    Full Text Available The complement system is a part of the innate immune system that viruses need to face during infections. Many viruses incorporate cellular regulators of complement activation (RCA to block complement pathways and our prior work has shown that Parainfluenza virus 5 (PIV5 incorporates CD55 and CD46 to delay complement-mediated neutralization. In this paper, we tested the role of a third individual RCA inhibitor CD59 in PIV5 interactions with complement pathways. Using a cell line engineered to express CD59, we show that small levels of functional CD59 are associated with progeny PIV5, which is capable of blocking assembly of the C5b-C9 membrane attack complex (MAC. PIV5 containing CD59 (PIV5-CD59 showed increased resistance to complement-mediated neutralization in vitro comparing to PIV5 lacking regulators. Infection of A549 cells with PIV5 and RSV upregulated CD59 expression. TGF-beta treatment of PIV5-infected cells also increased cell surface CD59 expression and progeny virions were more resistant to complement-mediated neutralization. A comparison of individual viruses containing only CD55, CD46, or CD59 showed a potency of inhibiting complement-mediated neutralization, which followed a pattern of CD55 > CD46 > CD59.

  20. [Fruit and vegetables intake among the Chinese migrant population aged 18 to 59 years old in 2012].

    Science.gov (United States)

    Zhang, Mei; Wang, Linhong; Deng, Qian; Zhao, Yinjun; Huang, Zhengjing; Li, Yichong; Jiang, Yong; Wang, Limin

    2014-11-01

    To describe the intake of fruit and vegetables among employed migrant population aged 18 to 59 year-olds in China. Data from the Migrant Population Survey related to China Chronic Disease and Risk Factor Surveillance that conducted in 170 counties/districts in 31 provinces, 2012, was used. Information on non-communicable diseases and related risk factors among migrant population were collected through face-to-face questionnaire interview, physical measurement and lab tests. A total of 48 704 subjects aged 18 to 59 years old were included in our study. Sample was standardized by age and sex. Information on average daily fruit and vegetables intake, prevalence of low fruit and vegetables intake, grouped by sex, age, industries, and education level were analyzed. The average daily intakes of vegetables and fruits were 353.7 (95%CI:351.3-356.2) g and 125.1 (95%CI:123.4-126.9) g respectively, among the employed migrant population aged 18-59 years old in China. Prevalence of low fruit and vegetables intake was 44.1% (95% CI:43.5%-44.6% ) among employed migrant population, 46.2% (95% CI: 45.5%-47.0%)for males and 41.2% (95% CI:40.3%-42.0%)for females (χ(2) = 82.19, P fruit and vegetables intake was the highest among people working in accommodation and restaurants (46.2%, 95%CI:45.0%-47.3%) while the lowest seen among those working in social services (42.5%, 95%CI:41.4%-43.7%,χ(2) = 15.81, P fruit and vegetables intake showed a decrease along with the increase of education levels (χ(2) = 22.29, P fruit and vegetables intake. Being male and with low education level were risk factors linked with the higher prevalence of low fruit and vegetables intake.

  1. A new 2DS·2RL Robertsonian translocation transfers stem rust resistance gene Sr59 into wheat.

    Science.gov (United States)

    Rahmatov, Mahbubjon; Rouse, Matthew N; Nirmala, Jayaveeramuthu; Danilova, Tatiana; Friebe, Bernd; Steffenson, Brian J; Johansson, Eva

    2016-07-01

    A new stem rust resistance gene Sr59 from Secale cereale was introgressed into wheat as a 2DS·2RL Robertsonian translocation. Emerging new races of the wheat stem rust pathogen (Puccinia graminis f. sp. tritici), from Africa threaten global wheat (Triticum aestivum L.) production. To broaden the resistance spectrum of wheat to these widely virulent African races, additional resistance genes must be identified from all possible gene pools. From the screening of a collection of wheat-rye (Secale cereale L.) chromosome substitution lines developed at the Swedish University of Agricultural Sciences, we described the line 'SLU238' 2R (2D) as possessing resistance to many races of P. graminis f. sp. tritici, including the widely virulent race TTKSK (isolate synonym Ug99) from Africa. The breakage-fusion mechanism of univalent chromosomes was used to produce a new Robertsonian translocation: T2DS·2RL. Molecular marker analysis and stem rust seedling assays at multiple generations confirmed that the stem rust resistance from 'SLU238' is present on the rye chromosome arm 2RL. Line TA5094 (#101) was derived from 'SLU238' and was found to be homozygous for the T2DS·2RL translocation. The stem rust resistance gene on chromosome 2RL arm was designated as Sr59. Although introgressions of rye chromosome arms into wheat have most often been facilitated by irradiation, this study highlights the utility of the breakage-fusion mechanism for rye chromatin introgression. Sr59 provides an additional asset for wheat improvement to mitigate yield losses caused by stem rust.

  2. Redo coloanal anastomosis for anastomotic leakage after low anterior resection for rectal cancer: an analysis of 59 cases.

    Science.gov (United States)

    Westerduin, E; Borstlap, W A A; Musters, G D; Westerterp, M; van Geloven, A A W; Tanis, P J; Wolthuis, A M; Bemelman, W A; D'Hoore, A

    2018-01-01

    The construction of a new coloanal anastomosis (CAA) following anastomotic leakage after low anterior resection (LAR) is challenging. The available literature on this topic is scarce. The aim of this two-centre study was to determine the clinical success and morbidity after redo CAA. This retrospective cohort study included all patients with anastomotic leakage after LAR for rectal cancer who underwent a redo CAA between 2010 and 2014 in two tertiary referral centres. Short- and long-term morbidity were analysed, including both anastomotic leakage and permanent stoma rates on completion of follow-up. A total of 59 patients were included, of whom 45 (76%) were men, with a mean age of 59 years (SD ± 9.4). The median interval between index and redo surgery was 14 months [interquartile range (IQR) 8-27]. The median duration of follow-up was 27 months (IQR 17-36). The most frequent complication was anastomotic leakage of the redo CAA occurring in 24 patients (41%), resulting in a median of three reinterventions (IQR 2-4) per patient. At the end of follow-up, bowel continuity was restored in 39/59 (66%) patients. Fourteen (24%) patients received a definitive colostomy and six (10%) still had a diverting ileostomy. In a multivariable model, leakage of the redo CAA was the only risk factor for permanent stoma (OR 0.022; 95% CI 0.004-0.122). Redo CAA is a viable option in selected patients with persisting leakage after LAR for rectal cancer who want their bowel continuity restored. However, patients should be fully informed about the relatively high morbidity and reintervention rates. Colorectal Disease © 2017 The Association of Coloproctology of Great Britain and Ireland.

  3. Determinants of anemia among 6-59 months aged children in Bangladesh: evidence from nationally representative data.

    Science.gov (United States)

    Khan, Jahidur Rahman; Awan, Nabil; Misu, Farjana

    2016-01-11

    Anemia is a global public health problem but the burden of anemia is disproportionately borne among children in developing countries. Anemia in early stages of life has serious consequences on the growth and development of the children. We examine the prevalence of anemia, possible association between anemia and different socio-economic, demographic, health and other factors among children with ages from 6 to 59 months from the nationally representative 2011 Bangladesh Demographic and Health Survey (BDHS). Data on hemoglobin (Hb) concentration among the children aged 6-59 months from the most recent BDHS (2011) were used. This nationally representative survey allowed a multistage stratified cluster sampling design and provided data on a wide range of indicators such as fertility, mortality, women and child health, nutrition and other background characteristics. Anemia status was determined using hemoglobin level (<11.0 g/dl), and weighted prevalence of childhood anemia along with 95 % confidence intervals were provided. We also examined the distribution of weighted anemia prevalence across different groups and performed logistic regression to assess the association of anemia with different factors. A total of 2171 children aged 6-59 months were identified for this analysis, with weighted prevalence of anemia being 51.9 % overall- 47.4 % in urban and 53.1 % in rural regions. Results of a multivariable logistic regression analysis showed that, children below 24 months of age (odds ratio, [OR] 3.01; 95 % confidence interval [CI] 2.38-3.81), and those from an anemic mother (OR 1.80; 95 % CI 1.49-2.18) were at higher risk of anemia. Childhood anemia was significantly associated with chronic malnutrition of child, source of drinking water, household wealth and geographical location (defined by division). A high prevalence of anemia among 6-59 months aged children was observed in Bangladesh. Given the negative impact of anemia on the development of children in

  4. X-ray fluorescence in some medium-Z elements excited by 59.5 keV photons

    International Nuclear Information System (INIS)

    Han, I.; Shahin, M.; Demir, L.; Narmanli, E.

    2010-01-01

    K X-ray fluorescence parameters cross sections and average shell fluorescence yields) for selected ten elements in the atomic range 42 ≤ Z ≤ 66 have been experimentally determined at photon excitation energy of 59.5 keV. K X-rays emitted from the samples have been counted by a Si (Li) detector. The K spectra for investigated elements have been derived from the measured K shell X-ray spectra by peak fitting process. Experimental results of K X-ray fluorescence parameters have been compared with theory. In general there is an agreement within the standard uncertainties of the experimental and theoretical values

  5. Magnetic fluctuations near a quantum phase transition in CeCu5.9Au0.1

    DEFF Research Database (Denmark)

    Schröder, A.; Aeppli, G.; Bucher, E.

    1998-01-01

    We present inelastic cold neutron scattering measurements on a single crystal of the heavy-fermion compound CeCu5.9Au0.1, where non-Fermi-liquid behavior near a quantum phase transition was found in the specific heat and resistivity. This compound shows strongly correlated magnetic fluctuations......, most intense at wave vectors Q(1), near(1,0,0), close to the magnetic ordering vector found at higher Au-concentration. The energy dependence can be best described by a modified quasielastic Lorentzian with power alpha = 0.7. Down to the lowest temperature of 0.07 K the relaxation rate Gamma remains...

  6. E2,M1 Multipole mixing ratios in odd-mass nuclei, 59< or =A< or =149

    International Nuclear Information System (INIS)

    Krane, K.S.

    1977-01-01

    A survey is presented of the E2,M1 mxing ratios of gamma-ray transitions in odd-mass nuclei with 59< or =A< or =149. Angular distribution and correlation data from the literature are analyzed in terms of a consistent choice of the phase relationship between the E2 and M1 matrix elements. A set of recommended values of the mixing ratios is included, based on averages of results from various studies. The survey includes data available in the literature up to September 1976

  7. Density determination in Pino Radiata (D.Don) samples using 59.5 keV gamma radiation attenuation

    International Nuclear Information System (INIS)

    Dinator, Maria I.; Morales, Jose R.; Aliaga, Nelson; Karsulovic, Jose T.; Sanchez, Jaime; Leon, Adolfo

    1996-01-01

    A non destructive method to determine wood samples density is presented. The photon mass attenuation coefficient in samples of Pino radiata (D.Don) was measured at 59.5 keV with a radioactive source of Am-241. The value of 0.192 ± 0.002 cm 2 /g was obtained with a gamma spectroscopy system and later used on the determination of the mass density in sixteen samples of the same species. Comparison of these results with those of gravimetric method through a linear regression showed a slope of 1.001 and a correlation factor of 0.94. (author)

  8. Unusual cause for recurrent Cushing syndrome and its diagnosis by computed tomography and NP-59 radiocholesterol scanning

    International Nuclear Information System (INIS)

    Harris, R.D.; Herwig, K.R.

    1990-01-01

    Cushing syndrome can recur following an adrenalectomy. One of the primary causes is recurrence of adrenal carcinoma either locally or from metastases. Hyperplasia and hyperfunction of adrenal remnants may also occur if there is pituitary stimulation. We have a patient in whom recurrent Cushing syndrome developed from small nonmalignant deposits of adrenal tissue in the perirenal adipose tissue following adrenalectomy of a benign adenoma. These deposits were identifiable by computed tomography. A false-negative NP-59 iodocholesterol scan was instructive in pointing out some problems in the interpretation of this type of scan for adrenal tissue

  9. A method to determine density in wood samples using attenuation of 59.5 KeV gamma radiation

    International Nuclear Information System (INIS)

    Dinator, M.I.; Morales, J.R.; Aliaga, N.; Karsulovic, J.T.; Sanchez, J.; Leon, L.A.

    1996-01-01

    A nondestructive method to determine the density of wood samples is presented. The photon mass attenuation coefficient in samples of Pino Radiata was measured at 59.5 KeV with a radioactive source of Am-241. The value of 0.192 ± 0.002 cm 2 /g was obtained with a gamma spectroscopy system and later used on the determination of the mass density in sixteen samples of the same species. Comparison of these results with those of gravimetric method through a linear regression showed a slope of 1.001 and correlation factor of 0.94. (author)

  10. [INCIDENCE OF CORONARY HEART DISEASE IN COMBINATION WITH TYPE 2 DIABETES MELLITUS ESTIMATED FROM RESULTS OF AN EPIDEMIOLOGICAL STUDY OF 20-59 YEAR OLD WOMEN].

    Science.gov (United States)

    Sultanova, S S; Kasumova, E N; Mamedova, R N

    2015-01-01

    We report evaluation of the incidence of coronary heart disease (CHD) in combination with type 2 diabetes mellitus (DM2) estimated from results of an epidemiological study of 20-59 year old women. CPD was shown to occur twice more frequently in association with DM2 especilly in the age groups of 30-39 and 50-59 years.

  11. Caterpillars and host plant records for 59 species of Geometridae (Lepidoptera) from a montane rainforest in southern Ecuador.

    Science.gov (United States)

    Bodner, Florian; Brehm, Gunnar; Homeier, Jürgen; Strutzenberger, Patrick; Fiedler, Konrad

    2010-01-01

    During four months of field surveys at the Reserva Biológica San Francisco in the south Ecuadorian Andes, caterpillars of 59 Geometridae species were collected in a montane rainforest between 1800 and 2800m altitude and reared to adults. The resulting data on host plant affiliations of these species was collated. The preimaginal stages of 58 and adult stages of all 59 species are depicted in colour plates. Observations on morphology and behaviour are briefly described. Five species, documented for the first time in the study area by means of larval collections, had not been previously collected by intensive light-trap surveys. Together with published literature records, life-history data covers 8.6% of the 1271 geometrid species observed so far in the study area. For 50 species these are the first records of their early stages, and for another 7 the data significantly extend known host plant ranges. Most larvae were collected on shrubs or trees, but more unusual host plant affiliations, such as ferns (6 geometrid species) and lichens (3 geometrid species), were also recorded. Thirty-four percent of the caterpillars were infested by wasp or tachinid parasitoids.

  12. Formation cross section of iron-60 with reactor neutrons in 59Fe(n, γ)60Fe reaction

    International Nuclear Information System (INIS)

    Sato, T.; Suzuki, T.

    1993-01-01

    Ingrowth of 60 Co radioactivity in an iron sample irradiated in a nuclear reactor has been measured for determination of formation cross section of 60 Fe in the 59 Fe(n, γ) 60 Fe reaction with reactor neutrons. After 5 years cooling, the irradiated iron was purified from 60 Co and other radioactive nuclides by an anion exchange separation method and isopropyl ether extraction in hydrochloric acid. The amount of 60 Co ingrowth was measured by γ-spectrometry using a Ge-detector coupled to a multichannel pulse height analyzer 4 years after the purification of iron. Neutron flux of the irradiation position was calculated from the amount of 55 Fe produced. The observed value of 12.5 ± 2.8 barn is slightly greater than reported value for burnup cross section of 59 Fe(n, x)X, where x refers γ, α, d, p and 2n, and X is any nuclide produced by the above reactions. (author) 8 refs.; 2 tabs

  13. Loss of 51Cr, 54Mn, 57Co, 59Fe, 65Zn and 134Cs by the mussel Mytilus

    International Nuclear Information System (INIS)

    Dahlgaard, H.

    1981-01-01

    The loss of 51 Cr, 54 Mn, 57 Co, 59 Fe, 65 Zn and 134 Cs from naturally growing mussels (Mytilus edulis) was followed in a temperate estuarine environment -a Danish fjord - by individual whole-body countings on a Ge(Li) detector. The mussels accumulated the radionuclides in the laboratory from food and water and were brought back to their natural environment in small plastic cages. The loss curves for 12 animals from July - August 1979 until November 1979 (20-5 0 C) were resolved in a slow compartment with 140-215 d biological half-life for 57 Co, 54 Mn, 51 Cr and 59 Fe, and 87 d for 65 Zn, and a medium compartment with a biological half-life of 4-7 d for all nuclides. The long-lived compartments of 65 Zn, 57 Co and 54 Mn were followed in four individual animals from August 1979 to August 1980. For 65 Zn a seasonal effect was clearly demonstrated as the biological half-life was prolonged from 87 d during autumn 1979 to 347 d in the cold period (0-5 0 C), whereas it decreased again during the summer of 1980. For 57 Co and 54 Mn the long-term excretion study revealed an extra-slow compartment, as the long half-life in the cold period (approximately 600 d) persisted during the summer of 1980. This is explained by association with the shell. (author)

  14. HIGH RESOLUTION NEAR-INFRARED SURVEY OF THE PIPE NEBULA. I. A DEEP INFRARED EXTINCTION MAP OF BARNARD 59

    International Nuclear Information System (INIS)

    Roman-Zuniga, Carlos G.; Alves, Joao F.; Lada, Charles J.

    2009-01-01

    We present our analysis of a fully sampled, high resolution dust extinction map of the Barnard 59 complex in the Pipe Nebula. The map was constructed with the infrared color excess technique applied to a photometric catalog that combines data from both ground and space based observations. The map resolves for the first time the high density center of the main core in the complex, which is associated with the formation of a small cluster of stars. We found that the central core in Barnard 59 shows an unexpected lack of significant substructure consisting of only two significant fragments. Overall, the material appears to be consistent with being a single, large core with a density profile that can be well fit by a King model. A series of NH 3 pointed observations toward the high column density center of the core appear to show that the core is still thermally dominated, with subsonic non-thermal motions. The stars in the cluster could be providing feedback to support the core against collapse, but the relatively narrow radio lines suggest that an additional source of support, for example, a magnetic field, may be required to stabilize the core. Outside the central core our observations reveal the structure of peripheral cores and resolve an extended filament into a handful of significant substructures whose spacing and masses appear to be consistent with Jeans fragmentation.

  15. Validity and reliability of Preschool Language Scale 4 for measuring language development in children 48-59 months of age

    Directory of Open Access Journals (Sweden)

    Nuryani Sidarta

    2016-04-01

    Full Text Available Prevalence rates for speech and language delay have been reported across wide ranges. Speech and language delay affects 5% to 8% of preschool children, often persisting into the school years.  A cross-sectional study was conducted in 208 children aged 48-59 months to determine the validity and reliability of the Indonesian edition of the Preschool Language Scale version 4 (PLS4 as a screening tool for the identification of language development disorders. Construct validity was examined by using Pearson correlation coefficient. Internal consistency was tested and repeated measurements were taken to establish the stability coefficient and intraclass correlation coefficients (ICC for test-retest reliability. For construct validity, the Pearson correlation coefficient ranged from 0.151-0.526, indicating that all questions in this instrument were valid for measuring auditory comprehension (AC and expressive communication skills (EC. Cronbach’s alpha level ranged from 0.81-0.95 with standard error of measurement (SEM ranging from 3.1-3.3. Stability coefficients ranged from 0.98-.0.99 with ICC coefficient ranging from 0.97-0.99 both of which showed an excellent reliability. This study found that PLS-4 is a valid and reliable instrument. It is easy to handle and can be recommended for assessing language development in children aged 48-59 months.

  16. 59th Annual Meeting

    Indian Academy of Sciences (India)

    1993-10-01

    Oct 1, 1993 ... understand the process of differentiation" ... Research, Bombay - Theoretical High Energy. Physics _ ... Problems and perspectives" by K V S Rao, ... communications". ... current research areas in the Indian context. The.

  17. KP59 METAR

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — METAR is a routine scheduled observation and is the primary observation code used in the United States to satisfy requirements for reporting surface meteorological...

  18. Indexes to Volume 59

    Indian Academy of Sciences (India)

    Critical exponents in the transition to chaos in one-dimensional discrete sys- tems. G Ambika and N V ... simulations of inertial confinement fusion plasmas. N K Gupta and B K ... An EBIS for charge state breeding in the SPES project. V Variale,.

  19. 59 - 62 lawan paid

    African Journals Online (AJOL)

    DR. AMIN

    development rather than seed germination. Key words: Allelochemicals, Eucalyptus species, Root length, Germination, Arachis hypogea. INTRODUCTION. Plants that ..... Bangladesh Journal of Botany, 33(2): 79-84. Ahmed, R., Uddin, M. B. ...

  20. D 59 Design Guidelines

    DEFF Research Database (Denmark)

    Burcharth, Hans F.; Lamberti, Alberto

    The present guidelines are specifically dedicated to Low Crested Structures on attempt to provide methodological tools both for the engineering design of structures and for prediction of performance and environmental impacts. It is anticipated that the guidelines will provide valuable inputs to c...

  1. Page 53 - 59.pmd

    African Journals Online (AJOL)

    Administrator

    Predictors of conformity were: duration in service of less than 6 years. (OR=3.40. CI=1.24-9.33), prescriber's profession (OR=97.51, CI=27.29-348.34) and diagnosis of uncomplicated malaria. (OR=10.13, CI=3.37-30.42). Conclusions: Adequate training and provision of information relevant to the needs of different cadres of ...

  2. The ORF59 DNA polymerase processivity factor homologs of Old World primate RV2 rhadinoviruses are highly conserved nuclear antigens expressed in differentiated epithelium in infected macaques

    Directory of Open Access Journals (Sweden)

    Burnside Kellie L

    2009-11-01

    Full Text Available Abstract Background ORF59 DNA polymerase processivity factor of the human rhadinovirus, Kaposi's sarcoma-associated herpesvirus (KSHV, is required for efficient copying of the genome during virus replication. KSHV ORF59 is antigenic in the infected host and is used as a marker for virus activation and replication. Results We cloned, sequenced and expressed the genes encoding related ORF59 proteins from the RV1 rhadinovirus homologs of KSHV from chimpanzee (PtrRV1 and three species of macaques (RFHVMm, RFHVMn and RFHVMf, and have compared them with ORF59 proteins obtained from members of the more distantly-related RV2 rhadinovirus lineage infecting the same non-human primate species (PtrRV2, RRV, MneRV2, and MfaRV2, respectively. We found that ORF59 homologs of the RV1 and RV2 Old World primate rhadinoviruses are highly conserved with distinct phylogenetic clustering of the two rhadinovirus lineages. RV1 and RV2 ORF59 C-terminal domains exhibit a strong lineage-specific conservation. Rabbit antiserum was developed against a C-terminal polypeptide that is highly conserved between the macaque RV2 ORF59 sequences. This anti-serum showed strong reactivity towards ORF59 encoded by the macaque RV2 rhadinoviruses, RRV (rhesus and MneRV2 (pig-tail, with no cross reaction to human or macaque RV1 ORF59 proteins. Using this antiserum and RT-qPCR, we determined that RRV ORF59 is expressed early after permissive infection of both rhesus primary fetal fibroblasts and African green monkey kidney epithelial cells (Vero in vitro. RRV- and MneRV2-infected foci showed strong nuclear expression of ORF59 that correlated with production of infectious progeny virus. Immunohistochemical studies of an MneRV2-infected macaque revealed strong nuclear expression of ORF59 in infected cells within the differentiating layer of epidermis corroborating previous observations that differentiated epithelial cells are permissive for replication of KSHV-like rhadinoviruses

  3. Assessment of Alveolar Bone Status in Middle Aged Chinese (40-59 Years with Chronic Periodontitis--Using CBCT.

    Directory of Open Access Journals (Sweden)

    Haijiao Zhao

    Full Text Available This study used con-beam computed tomography (CBCT to investigate the prevalence and severity of alveolar bone loss in middle-aged (40-59 years Chinese with chronic periodontitis.The study group comprised 145 dentate individuals aged 40 to 59 years residing in China who suffered from chronic periodontitis. CBCT and the application of NNT software were used to examine the level and location of alveolar bone loss.The study revealed that 40-59 year old patients with chronic periodontitis had severe bone loss. At 5,286 sites (34.7%, alveolar bone loss was mild; severe alveolar bone loss was found at 5,978 sites (39.2%. A comparison of bone loss in different jaws revealed that the area with the highest degree of bone loss was on the lingual side of the maxillary molar (56.3 ± 7.2%, and that the area with the lowest degree was primarily on the lingual side of the mandibular canine (27.5 ± 6.3%. There was a lower degree of alveolar bone loss in males than females. Differences were observed when comparing the incidence of bone loss between males and females (P < 0.05. Menopause in females and smoking in both genders may affect the level of bone loss. Male smokers experienced a greater degree of bone loss (41.67 ± 5.76% than male non-smokers (32.95 ± 4.31%. A 42.23 ± 6.34% bone loss was found in menopausal females versus 31.35 ± 3.62% in non-menopausal females.The study revealed that different sites and teeth exhibited a diverse degree of bone loss. In middle-aged patients with chronic periodontitis, the highest degrees of bone loss in the incisors, premolars, and molars were on the lingual side, mesial side and lingual side, respectively. Menopause in females and smoking may affect the level of bone loss.

  4. Epidemiologic evaluation ABCC and Nagasaki University School of Medicine autopsies and ABCC surgical specimens: Nagasaki 1950-59

    Energy Technology Data Exchange (ETDEWEB)

    Samther, T G; Hrubec, Zdenek; Brown, W J; Thomas, G D

    1962-08-22

    This epidemiologic evaluation covered autopsies performed at ABCC Nagasaki and at the Nagasaki University School of Medicine, as well as surgical pathology specimens examined at ABCC Nagasaki during 1950-59. The material was related to the ABCC Master Sample population. Bias was demonstrated with respect to symptom status, exposure, age, death certificate diagnosis, male occupations, and history of previous medical examinations at ABCC. In addition the ABCC autopsy series was found to be biased with regard to sex. Comparison with data from Hiroshima indicated similar bias which is possibly more pronounced in Hiroshima. On the basis of these findings, it was concluded that at this time the material is not suitable for broad epidemiologic studies of clinically manifest disease. The material, however, does lend itself to a number of studies of clinically occult disease and other problems which were discussed. 19 references, 32 tables.

  5. Clinical evaluation of MPT-64 and MPT-59, two proteins secreted from Mycobacterium tuberculosis, for skin test reagents

    DEFF Research Database (Denmark)

    Wilcke, J T; Jensen, B N; Ravn, P

    1996-01-01

    : In a small scale clinical investigation, skin reactions to these antigens were compared to reactions to tuberculin PPD RT23 in 1) patients with active tuberculosis, 2) BCG vaccinated healthy subjects with close contact with tuberculous patients, and 3) BCG vaccinated healthy subjects without contact...... with tuberculous patients. Tests for in vitro reactivity to these antigens were carried out in similar groups. RESULTS: All subjects gave positive reaction to tuberculin PPD RT23, whereas approximately half of the subjects in each of the three groups reacted to MPT-59. Two subjects (one patient with tuberculosis...... and one healthy bacille Calmette-Guérin vaccinated subject without patient contact) reacted to MPT-64. The studies of cell proliferation and induction of interferon-gamma (IFN-gamma) following stimulation with tuberculin PPD and MPT-64 supported this profile of reactivity. CONCLUSION: None...

  6. Similarity of /sup 241/Am and /sup 59/Fe speciation in selected freshwaters and of their adsorption on crayfish exoskeleton

    Energy Technology Data Exchange (ETDEWEB)

    Vangenechten, J.H.D.; Chughtai, N.A.; Bierkens, J.; Vanderborght, O.L.J.

    1987-01-01

    The particulate fraction and the organically complexed fraction of freshly added /sup 241/Am and /sup 59/Fe were determined in 21 prefiltered surface waters. The adsorptive behaviour of both radionuclides on a biological surface (isolated carapace segments of crayfish) was tested simultaneously. A striking similarity was observed in the chemical and absorptive behaviours of both radionuclides. The stoichiometry of particulate formation revealed a 3/4, Am to Fe ratio. This same stoichiometric relationship was observed in organic complexation, while adsorptive behaviour was characterised by a 1/1, Am to Fe ratio. It is concluded that Am predictably follows the chemistry of freshly added Fe at least over a 15 day period. This observation may find interesting application in risk assessment where use can be made of the well-known geochemical cycling of iron to predict the behaviour of man-made Am.

  7. Similarity of 241Am and 59Fe speciation in selected freshwaters and of their adsorption on crayfish exoskeleton

    International Nuclear Information System (INIS)

    Vangenechten, J.H.D.; Chughtai, N.A.; Bierkens, J.; Vanderborght, O.L.J.

    1987-01-01

    The particulate fraction and the organically complexed fraction of freshly added 241 Am and 59 Fe were determined in 21 prefiltered surface waters. The adsorptive behaviour of both radionuclides on a biological surface (isolated carapace segments of crayfish) was tested simultaneously. A striking similarity was observed in the chemical and absorptive behaviours of both radionuclides. The stoichiometry of particulate formation revealed a 3/4, Am to Fe ratio. This same stoichiometric relationship was observed in organic complexation, while adsorptive behaviour was characterised by a 1/1, Am to Fe ratio. It is concluded that Am predictably follows the chemistry of freshly added Fe at least over a 15 day period. This observation may find interesting application in risk assessment where use can be made of the well-known geochemical cycling of iron to predict the behaviour of man-made Am. (author)

  8. Decolorization of humic acids and alkaline lignin derivative by an anamorphic Bjerkandera adusta E59 strain isolated from soil

    Energy Technology Data Exchange (ETDEWEB)

    Kornillowicz-Kowalska, T.; Ginalska, G.; Belcarz, A.; Iglik, H. [University of Life Sciences, Lublin (Poland). Dept. of Microbiology

    2008-07-01

    An anamorphic Bjerkandera adusta R59 strain, isolated from soil, was found to decolorize post-industrial lignin alkaline fraction, humic acids isolated from two kinds of soil and from brown coal. The drop of methoxyphenolic compound levels in liquid B. adusta cultures containing lignin or humic acids was correlated with decolorization of studied biopolymers, which suggests their partial biodegradation. It was shown that this process was Coupled with the induction of secondary metabolism (idiophase), and highest peroxidase activity in culture medium and appearance of aerial mycelium. Decolorization of lignin and humic acids from lessive soil and brown coal depended on glucose presence (cometabolism). Decolorization of humic acid from chernozem was related partially to adsorption by fungal mycelium.

  9. Gamma spectrometry analysis for simultaneous detection of 54Mn, 65Zn and 59Fe in aqueous solutions and plant tissues

    International Nuclear Information System (INIS)

    Montanheiro, M.N.S.

    1975-01-01

    A methodology to detect the activities of 54 Mn, 65 Zn and 59 Fe in the same sample, with a single channel spectrometer coupled to a scintilation detector of NaI(tl), 3'' x 3'', well type has been developed. Initially a selection of the energy channel was made based on the criteria of maximizing the signal-background ratio and consequently, the minimization of the variation coefficient. In the channels, a study of minimal detectable activities was conducted for each radioisotopes. Secondly, samples containing diferent combinations of these radioisotopes were prepared and their activities were calculated using simultaneous equations. As a mean of demonstrating the pratical utility of this methodology, an experiment was developed in which the roots, isolated from beam plants (Phaseolus vulgaris, L.) were examined to determine levels of ionic absorption interference among micronutrients (Mn, Zn and Fe)

  10. Compact galaxies in the region with the center coordinates 07sup(h)59sup(m)+54 deg 44'

    International Nuclear Information System (INIS)

    Boerngen, F.; Kalloglyan, A.T.

    1980-01-01

    A list of 70 compact galaxies is presented, galaxies being found in the metagalactic field in the region with center coordinates αsub(1950)=07sup(h)59sup(m), deltasub(1950)54 deg 44'. The selection of objects have been carried out on negatives obtained in the Schmidt focus of the two-meter universal telescope of Tautenburg observatory in the colour B and V system. Galaxies of the highest surface brightness and of spherical configuration have been included. Only in some cases slightly elongated objects have been included due to their very high surface brightness. The coordinates, B and V stellar values of all objects have been measured. The maps of their identification are presented

  11. Immunity against diphtheria and tetanus in human immunodeficiency virus-infected Danish men born 1950-59

    DEFF Research Database (Denmark)

    Kurtzhals, J A; Kjeldsen, K; Heron, I

    1992-01-01

    To evaluate the possible need for vaccination against diphtheria and tetanus of patients infected with the human immunodeficiency virus (HIV), antibodies were measured in blood samples from 78 Danish HIV-infected men, born 1950-59, who could be expected to have received primary vaccination before...... they contracted the HIV infection. No patients (95% confidence interval: 0-4) had tetanus antibodies below the protective level, whereas 24 of the 78 patients (16-33) were unprotected against diphtheria. In the background population of the same age group and sex, 5% and 10% have been found unprotected against...... tetanus and diphtheria, respectively. No relationship between disease stages and antibody levels could be found. Neither was there any difference between patients with normal and reduced numbers of CD4+ lymphocytes. From 25 patients two blood samples were taken at an interval of at least one year. Anti...

  12. Changes in Polish law related to the implementation of COUNCIL DIRECTIVE 2013/59/EURATOM of 5 December 2013

    Science.gov (United States)

    Wołoszczuk, Katarzyna; Skubacz, Krystian; Podgórska, Zuzanna

    2018-01-01

    Radon is an invisible, naturally occurring radioactive noble gas. According to the WHO report, it is the most important cause of lung cancer after smoking [1]. Recent epidemiological studies show that a statistically significant increase in the risk of lung cancer already occurs as a result of prolonged exposure to radon inside rooms where the concentration is at 100 Bq/m3 and increases by 16% per 100 Bq/m3 increase (considering a prolonged exposure period). For this reason, the Council Directive 2013/59/Euratom (BSS) [2] establishing the basic safety standards for the protection against the hazards related to ionizing radiation, that was passed in 2013, pays particular attention to issues related to radon exposure. BSS reduce radon concentration limits in workplaces to 300 Bq/m3. According to the regulations in force, the BSS must be implemented in the Polish Atomic Law no later than 6th February 2018.

  13. Expression of CD55, CD59, and CD35 on red blood cells of β-thalassaemia patients

    Science.gov (United States)

    Koçtekin, Belkls; Kurtoǧlu, Erdal; Yildiz, Mustafa; Bozkurt, Selen

    2017-01-01

    Aim of the study β-thalassaemia (β-Thal) is considered a severe, progressive haemolytic anaemia, which needs regular blood transfusions for life expectancy. Complement-mediated erythrocyte destruction can cause both intravascular and extravascular haemolysis. Complement regulatory proteins protect cells from such effects of the complement system. We aimed to perform quantitative analysis of membrane-bound complement regulators, CD55 (decay accelerating factor – DAF), CD35 (complement receptor type 1 – CR1), and CD59 (membrane attack complex inhibitory factor – MACIF) on peripheral red blood cells by flow cytometry. Material and methods The present study was carried out on 47 β-thalassemia major (β-TM) patients, 20 β-thalassaemia intermedia (β-TI) patients, and 17 healthy volunteers as control subjects. Results CD55 levels of β-TM patients (58.64 ±17.06%) were significantly decreased compared to β-TI patients (83.34 ±13.82%) and healthy controls (88.57 ±11.69%) (p < 0.01). CD59 levels of β-TM patients were not significantly different than β-TI patients and controls, but CD35 levels were significantly lower in the β-TM patients (3.56 ±4.87%) and β-TI patients (12.48 ±9.19%) than in the control group (39.98 ±15.01%) (p < 0.01). Conclusions Low levels of CD55 and CD35 in thalassaemia major patients indicates a role for them in the aetiopathogenesis of haemolysis in this disease, and also this defect in a complement system may be responsible for the chronic complications seen in these patients. PMID:28680334

  14. Colonization and diversification of aquatic insects on three Macaronesian archipelagos using 59 nuclear loci derived from a draft genome.

    Science.gov (United States)

    Rutschmann, Sereina; Detering, Harald; Simon, Sabrina; Funk, David H; Gattolliat, Jean-Luc; Hughes, Samantha J; Raposeiro, Pedro M; DeSalle, Rob; Sartori, Michel; Monaghan, Michael T

    2017-02-01

    The study of processes driving diversification requires a fully sampled and well resolved phylogeny, although a lack of phylogenetic markers remains a limitation for many non-model groups. Multilocus approaches to the study of recent diversification provide a powerful means to study the evolutionary process, but their application remains restricted because multiple unlinked loci with suitable variation for phylogenetic or coalescent analysis are not available for most non-model taxa. Here we identify novel, putative single-copy nuclear DNA (nDNA) phylogenetic markers to study the colonization and diversification of an aquatic insect species complex, Cloeon dipterum L. 1761 (Ephemeroptera: Baetidae), in Macaronesia. Whole-genome sequencing data from one member of the species complex were used to identify 59 nDNA loci (32,213 base pairs), followed by Sanger sequencing of 29 individuals sampled from 13 islands of three Macaronesian archipelagos. Multispecies coalescent analyses established six putative species. Three island species formed a monophyletic clade, with one species occurring on the Azores, Europe and North America. Ancestral state reconstruction indicated at least two colonization events from the mainland (to the Canaries, respectively Azores) and one within the archipelago (between Madeira and the Canaries). Random subsets of the 59 loci showed a positive linear relationship between number of loci and node support. In contrast, node support in the multispecies coalescent tree was negatively correlated with mean number of phylogenetically informative sites per locus, suggesting a complex relationship between tree resolution and marker variability. Our approach highlights the value of combining genomics, coalescent-based phylogeography, species delimitation, and phylogenetic reconstruction to resolve recent diversification events in an archipelago species complex. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. PEMAKNAAN PSAK NO. 59 “MUDHARABAH” DALAM PERSPEKTIF KEADILAN (Studi Pada Baitul Maal Wat Tamwil Sidogiri Daerah Bangkalan

    Directory of Open Access Journals (Sweden)

    Fauzan Adhim

    2008-12-01

    Full Text Available Penelitian ini bertujuan untuk mengetahui tentang bagaimana penerapan dari sistem pembiayaan mudharabah pada Baitul Maal wat Tamwil Sidogiri Daerah Bangkalan ditinjau dari Pernyataan Standar Akutansi Keuangan (PSAK No.59. Penelitian ini dilakukan dengan menggunakan pendekatan Interpretive-Phenomenologik. Pendekatan ini dimaksudkan untuk mengetahui dan mengkaji secara langsung melalui ungkapan-ungkapan mengenai fenomena yang sesungguhnya terjadi dalam lingkungan operasionalisasi Baitul Maal wat Tamwil Sidogiri Daerah Bangkalan, khususnya pada pembiayaan mudharabah dalam konteks pengakuaan, pengukuran, penyajian dan pengungkapan.Hasil penelitian ini mengungkapkan bahwa pembiayaan mudharabah Baitul Maal wat Tamwil Sidogiri Daerah Bangkalan mencapai 80% dari seluruh total pembiayaan. Hal ini sangat berbeda dengan hasil penelitian yang telah dilakukan pada beberapa perbankan syari’ah ditanah air pada umumnya dominan pada pembiayaan murabaha/jual-beli (non-profit sharing yang berkisar rata-rata antara 65,66%. Dalam konteks pengakuan, pembiayaan muradhabah  diakui pada saat pembayaran kas atau penyerahan aktiva non-kas kepada pengelola dana, dan pembiayaan muradhabah yang diberikan secara bertahap diakui pada setiap tahap pembayaran atau penyerahan. Dalam hal pengukuran, pihak bank (mudharib tidak melakukan pencadangan pendapatan. Dalam konteks penyajian, pembiayaan mudharabah Baitul Maal wat Tamwil Sidogiri Daerah Bangkalan menekankan ketentuan dalam Al Quran surat Luqman ayat 34 yang artinya, “Dan tidak seorangpun yang dapat yang dapat mengetahui (dengan pasti apa yang diusahakan besok”. Sedangkan dalam konteks pengungkapan dalam pembiayaan mudharabah, Baitul Maal wat Tamwil Sidogiri Daerah Bangkalan  menekankan pada factor kejujuran dan transparasi terhadap seluruh elemen laporan keuangan yang tertuang dalam PSAK No.59.

  16. The Constitutional Review Chamber of the Republic of Estonia : no. of the case 3-2-1-59-04 : date of decision 18 March 2005

    Index Scriptorium Estoniae

    2004-01-01

    Riigikohtu lahendi 3-2-1-59-04 (Eesti Vabariik ja AS Desintegraator kassatsioonkaebused Tallinna Ringkonnakohtu tsiviilkolleegiumi 12. 12. 2003 otsusele AS Desintegraator hagis Eesti Vabariigi vastu 411 000 krooni väljamõistmiseks) tekst inglise keeles

  17. Tent Preservation Project - Demonstration/Validation for Replacement of Aqueous Copper 8 Quinolinolate Treatment of Cotton Webbing With RO-59-WP

    National Research Council Canada - National Science Library

    Bosselman, Suzanne E

    2008-01-01

    .... This report describes a demonstration/validation study of an alternative coating, RO-59-WP, as a potential additive to or replacement for Copper 8, which has been taken off the market several times...

  18. 2018-02-21T23:40:59Z https://www.ajol.info/index.php/all/oai oai:ojs ...

    African Journals Online (AJOL)

    article/102623 2018-02-21T23:40:59Z ujah:ART Grammatical Metaphor in SFL: A Rhetorical Resource for Academic Writing Ezeifeka, CR grammatical metaphor, nominalization, abstracts, information density, ideational metaphor, academic ...

  19. Immunogenicity and safety of cell-derived MF59®-adjuvanted A/H1N1 influenza vaccine for children

    Science.gov (United States)

    Knuf, Markus; Leroux-Roels, Geert; Rümke, Hans; Rivera, Luis; Pedotti, Paola; Arora, Ashwani Kumar; Lattanzi, Maria; Kieninger, Dorothee; Cioppa, Giovanni Della

    2015-01-01

    Mass immunization of children has the potential to decrease infection rates and prevent the transmission of influenza. We evaluated the immunogenicity, safety, and tolerability of different formulations of cell-derived MF59-adjuvanted and nonadjuvanted A/H1N1 influenza vaccine in children and adolescents. This was a randomized, single-blind, multicenter study with a total of 666 healthy subjects aged 6 months–17 y in one of 3 vaccination groups, each receiving formulations containing different amounts of influenza A/H1N1 antigen with or without MF59. A booster trivalent seasonal MF59 vaccine was administered one year after primary vaccinations. Antibody titers were assessed by hemagglutination inhibition (HI) and microneutralization assays obtained on days 1, 22, 43, 366, and 387 (3 weeks post booster). Safety was monitored throughout the study. One vaccination with 3.75 μg of A/H1N1 antigen formulated with 50% MF59 (3.75_halfMF59) or 7.5 μg of A/H1N1 antigen formulated with 100% MF59 (7.5_fullMF59) induced an HI titer ≥1:40 in >70% of children in the 1–vaccinations with nonadjuvanted 15 μg A/H1N1 antigen were needed to achieve this response in the 1–children aged 6–11 months, 1 dose of 7.5_fullMF59 resulted in an HI titer ≥1:40 in >70% while 2 doses of 3.75_halfMF59 were required to achieve this result. All vaccines were well tolerated. Our findings support the immunogenicity and safety of the 3.75_halfMF59 (2 doses for children vaccine formulations for use in children and adolescents aged 6 months to 17 y The use of the 3.75_halfMF59 could have the benefit of antigen and adjuvant sparing, increasing the available vaccine doses allowing vaccination of more people. PMID:25621884

  20. Vaccination coverage among children aged 13 to 59 months in Buenos Aires, Argentina, 2002 La cobertura de la vacunación en niños de 13 a 59 meses de edad en Buenos Aires, Argentina, en 2002

    Directory of Open Access Journals (Sweden)

    Gustavo H. Dayan

    2004-09-01

    Full Text Available OBJECTIVES: To estimate antigen-specific and series-complete vaccination coverage among children aged 13 to 59 months in Buenos Aires; to compare the results of a community-based household survey with coverage rates obtained from administrative records; and to identify risk factors for incomplete vaccination. METHODS: Census tracts in Buenos Aires were surveyed systematically in March and April, 2002. Three children aged 13 to 24 months and 25 to 59 months were surveyed per block in each census tract. Written documentation of vaccination was required. Risk factors associated with incomplete vaccination were identified with univariate analysis and multivariate logistic regression. RESULTS: A total of 1391 children were surveyed. Antigen-specific coverage ranged from 69.4% (95% CI 66.7%-72% for Haemophilus influenzae type b vaccination to 99% (95% CI 98.4%-99.6% for BCG vaccination. Except for measles, coverage estimates found in the survey did not differ substantially from those obtained from city health authority records. Multivariate logistic regression analysis showed child's age (P OBJETIVOS: Calcular la cobertura con el régimen de vacunación completo y con vacunas contra antígenos particulares en niños de 13 a 59 meses de edad en Buenos Aires; comparar los resultados de una encuesta comunitaria a domicilio con los porcentajes de cobertura indicados en los registros públicos; e identificar los factores que ponen a los niños en riesgo de no recibir todas las dosis de vacunas recomendadas bajo el régimen oficial. MÉTODOS: Se encuestaron sistemáticamente los corredores censales en Buenos Aires en marzo y abril de 2002. En cada cuadra de cada corredor censal se encuestó a tres niños entre las edades de 13 a 24 meses y de 25 a 29 meses. Se solicitaba ver una constancia de vacunación escrita. Se identificaron factores de riesgo asociados con la falta de vacunación completa mediante un análisis unifactorial y regresión log