WorldWideScience

Sample records for satellites cell phones

  1. Cell phone explosion.

    Science.gov (United States)

    Atreya, Alok; Kanchan, Tanuj; Nepal, Samata; Pandey, Bhuwan Raj

    2016-03-01

    Cell phone explosions and resultant burn injuries are rarely reported in the scientific literature. We report a case of cell phone explosion that occurred when a young male was listening to music while the mobile was plugged in for charging.

  2. Adventures with Cell Phones

    Science.gov (United States)

    Kolb, Liz

    2011-01-01

    Teachers are finding creative ways to turn the basic cell phone from a digital distraction into a versatile learning tool. In this article, the author explains why cell phones are important in learning and suggests rather than banning them that they be integrated into learning. She presents activities that can be done on a basic cell phone with a…

  3. Cell phones and cancer

    Science.gov (United States)

    Cancer and cell phones; Do cell phones cause cancer? ... Several major studies show no link between cell phones and cancer at this time. However, since the information available is based on short-term studies, the impact of many years of ...

  4. Cell Phones for Education

    Science.gov (United States)

    Roberson, James H.; Hagevik, Rita A.

    2008-01-01

    Cell phones are fast becoming an integral part of students' everyday lives. They are regarded as important companions and tools for personal expression. School-age children are integrating the cell phone as such, and thus placing a high value on them. Educators endeavor to instill in students a high value for education, but often meet with…

  5. Cell Phone RF Radiation

    Science.gov (United States)

    Abdul-Razzaq, Wathiq

    2015-01-01

    In a recent article in "Physics Today," Meredith and Redish emphasized the need to make introductory physics courses beneficial for life sciences majors. In this study, a lab activity is proposed to measure the intensity of electromagnetic waves emitted by cell phones and connect these measurements to various standards, biological…

  6. Cell Phone RF Radiation

    Science.gov (United States)

    Abdul-Razzaq, Wathiq

    2015-01-01

    In a recent article in "Physics Today," Meredith and Redish emphasized the need to make introductory physics courses beneficial for life sciences majors. In this study, a lab activity is proposed to measure the intensity of electromagnetic waves emitted by cell phones and connect these measurements to various standards, biological…

  7. Cell Phone Detection Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Pratt, Richard M.; Bunch, Kyle J.; Puzycki, David J.; Slaugh, Ryan W.; Good, Morris S.; McMakin, Douglas L.

    2007-10-01

    A team composed of Rick Pratt, Dave Puczyki, Kyle Bunch, Ryan Slaugh, Morris Good, and Doug McMakin teamed together to attempt to exploit cellular telephone features and detect if a person was carrying a cellular telephone into a Limited Area. The cell phone’s electromagnetic properties were measured, analyzed, and tested in over 10 different ways to determine if an exploitable signature exists. The method that appears to have the most potential for success without adding an external tag is to measure the RF spectrum, not in the cell phone band, but between 240 and 400MHz. Figures 1- 7 show the detected signal levels from cell phones from three different manufacturers.

  8. Cell phones: modern man's nemesis?

    Science.gov (United States)

    Makker, Kartikeya; Varghese, Alex; Desai, Nisarg R; Mouradi, Rand; Agarwal, Ashok

    2009-01-01

    Over the past decade, the use of mobile phones has increased significantly. However, with every technological development comes some element of health concern, and cell phones are no exception. Recently, various studies have highlighted the negative effects of cell phone exposure on human health, and concerns about possible hazards related to cell phone exposure have been growing. This is a comprehensive, up-to-the-minute overview of the effects of cell phone exposure on human health. The types of cell phones and cell phone technologies currently used in the world are discussed in an attempt to improve the understanding of the technical aspects, including the effect of cell phone exposure on the cardiovascular system, sleep and cognitive function, as well as localized and general adverse effects, genotoxicity potential, neurohormonal secretion and tumour induction. The proposed mechanisms by which cell phones adversely affect various aspects of human health, and male fertility in particular, are explained, and the emerging molecular techniques and approaches for elucidating the effects of mobile phone radiation on cellular physiology using high-throughput screening techniques, such as metabolomics and microarrays, are discussed. A novel study is described, which is looking at changes in semen parameters, oxidative stress markers and sperm DNA damage in semen samples exposed in vitro to cell phone radiation.

  9. CELL PHONE ADDICTION: A REVIEW

    Directory of Open Access Journals (Sweden)

    JOSE DE SOLA

    2016-10-01

    Full Text Available We present a review of the studies that have been published about addiction to cell phones. We analyse the concept of cell phone addiction as well as its prevalence, study methodologies, psychological features and associated psychiatric comorbidities. Research in this field has generally evolved from a global view of the cell phone as a device to its analysis via applications and contents. The diversity of criteria and methodological approaches that have been used is notable, as is a certain lack of conceptual delimitation that has resulted in a broad spread of prevalent data. There is a consensus about the existence of cell phone addiction, but the delimitation and criteria used by various researchers vary. Cell phone addiction shows a distinct user profile that differentiates it from Internet addiction. Without evidence pointing to the influence of cultural level and socioeconomic status, the pattern of abuse is greatest among young people, primarily females. Intercultural and geographical differences have not been sufficiently studied. The problematic use of cell phones has been associated with personality variables such as extraversion, neuroticism, self-esteem, impulsivity, self-identity and self-image. Similarly, sleep disturbance, anxiety, stress, and, to a lesser extent, depression, which are also associated with Internet abuse, have been associated with problematic cell phone use. In addition, the present review reveals the coexistence relationship between problematic cell phone use and substance use such as tobacco and alcohol.

  10. Biometric Security for Cell Phones

    Directory of Open Access Journals (Sweden)

    2009-01-01

    Full Text Available Cell phones are already prime targets for theft. The increasing functionality of cell phones is making them even more attractive. With the increase of cell phone functionality including personal digital assistance, banking, e-commerce, remote work, internet access and entertainment, more and more confidential data is stored on these devices. What is protecting this confidential data stored on cell phones? Studies have shown that even though most of the cell phone users are aware of the PIN security feature more than 50% of them are not using it either because of the lack of confidence in it or because of the inconvenience. A large majority of those users believes that an alternative approach to security would be a good idea.

  11. Epidemic of cell phone virus

    Science.gov (United States)

    Wang, Pu; González, Marta; Barabási, Albert-László.

    2008-03-01

    Standard operating systems and Bluetooth technology will be a trend for future cell phone features. These will enable cell phone viruses to spread either through SMS or by sending Bluetooth requests when cell phones are physically close enough. The difference in spreading methods gives these two types of viruses' different epidemiological characteristics. SMS viruses' spread is mainly based on people's social connections, whereas the spreading of Bluetooth viruses is affected by people's mobility patterns and population distribution. Using cell phone data recording calls, SMS and locations of more than 6 million users, we study the spread of SMS and Bluetooth viruses and characterize how the social network and the mobility of mobile phone users affect such spreading processes.

  12. Cell phone based balance trainer

    National Research Council Canada - National Science Library

    Lee, Beom-Chan; Kim, Jeonghee; Chen, Shu; Sienko, Kathleen H

    2012-01-01

    ..., weight, complexity, calibration procedures, cost, and fragility. We have designed and developed a cell phone based vibrotactile feedback system for potential use in balance rehabilitation training in clinical and home environments...

  13. No Phone Zone: Controlling Cell Phone Use in Academic Libraries

    Science.gov (United States)

    Heaton, Shelley; Master, Nancy

    2006-01-01

    This article reports the results of a survey of cell phone policies in university libraries conducted over a three-month period in 2005. The authors sought information about the libraries' problems regarding cell phone use and attendant noise by students and other library users. The authors began with an 18-question survey of one hundred…

  14. Do Cell Phones Cause Cancer?

    CERN Document Server

    Leikind, Bernard

    2010-01-01

    Do cell phones, household electrical power wiring or appliance, or high voltage power lines cause cancer? Fuggedaboudit! No way! When pigs fly! When I'm the Pope! Don't text while you're driving, however, or eat your cell phone. All organisms absorb microwave radiation directly as thermal energy. In living organisms, the organisms' thermal control systems, including the blood flow, and various cooling mechanisms, such as sweating in humans, that work to maintain a stable body temperature rapidly transfer the absorbed energy to the environment. Any temperature rise is small or even unobserved. Any proposed mechanism by which cell phone radiation might cause cancer must begin with this fact. But the amount of radiation absorbed from a cell phone is less than that produced by normal metabolic processes, and much less than that produced by, for example, exercise. None of these normal metabolic processes cause cancer. Therefore, the much smaller amounts of energy from cell phones doesn't cause cancer either. All f...

  15. Cell phones: the psychosocial risks.

    Science.gov (United States)

    Sansone, Randy A; Sansone, Lori A

    2013-01-01

    Cell phones are a relatively novel and evolving technology. While the potential benefits of this technology continue to emerge, so do the potential psychosocial risks. For example, one psychosocial risk is user stress, which appears to be related to feeling compelled to promptly respond to cell-phone activity in order to maintain spontaneity and access with others. Other potential psychosocial risks include disruptions in sleep; the user's risk of exposure to cyberbullying, particularly the unwanted exposure of photographs and/or videos of the victim; and overuse, particularly among adolescents. With regard to the latter phenomenon, the boundaries among overuse, misuse, dependence, and addiction are not scientifically clear. Therefore, while cell phones are a convenient and expedient technology, they are not without their potential psychosocial hazards.

  16. Completely Enhanced Cell Phone Keypad

    CERN Document Server

    Sharmeen, Rezwana; Ahmad, Shabbir; Kamruzzaman, S M

    2010-01-01

    The enhanced frequency based keypad is designed to speed up the typing process. This paper will show that the proposed layout will increase the typing speed and be flexible for thumb. Traditional cell phone keypad is not a scientific keypad from the frequency point of view. Approaches have been explored to speed up the typing process. We found that no manufacturer has considered the frequency of the alphabet. The current architecture does not provide flexibility although the users are accustomed to the currently available multi-tapping keypad. Since the currently available keypad layouts are not best suited for users, this paper will suggest a keypad for cell phone and other cellular device based on the frequency of the alphabet in English language and also with the view of structure of human finger movements to provide a flexible and fast cell phone keypad. It also takes into consideration the key jamming problem that was available in typewriter. At first we identified those keys of cell phone, which are eas...

  17. Cell-Phone Addiction: A Review.

    Science.gov (United States)

    De-Sola Gutiérrez, José; Rodríguez de Fonseca, Fernando; Rubio, Gabriel

    2016-01-01

    We present a review of the studies that have been published about addiction to cell phones. We analyze the concept of cell-phone addiction as well as its prevalence, study methodologies, psychological features, and associated psychiatric comorbidities. Research in this field has generally evolved from a global view of the cell phone as a device to its analysis via applications and contents. The diversity of criteria and methodological approaches that have been used is notable, as is a certain lack of conceptual delimitation that has resulted in a broad spread of prevalent data. There is a consensus about the existence of cell-phone addiction, but the delimitation and criteria used by various researchers vary. Cell-phone addiction shows a distinct user profile that differentiates it from Internet addiction. Without evidence pointing to the influence of cultural level and socioeconomic status, the pattern of abuse is greatest among young people, primarily females. Intercultural and geographical differences have not been sufficiently studied. The problematic use of cell phones has been associated with personality variables, such as extraversion, neuroticism, self-esteem, impulsivity, self-identity, and self-image. Similarly, sleep disturbance, anxiety, stress, and, to a lesser extent, depression, which are also associated with Internet abuse, have been associated with problematic cell-phone use. In addition, the present review reveals the coexistence relationship between problematic cell-phone use and substance use such as tobacco and alcohol.

  18. Cell Phones Transform a Science Methods Course

    Science.gov (United States)

    Madden, Lauren

    2012-01-01

    A science methods instructor intentionally encouraged cell phone use for class work to discover how cell phones can be used as research tools to enhance the content and engage the students. The anecdotal evidence suggested that students who used their smartphones as research tools experienced the science content and pedagogical information…

  19. Cell Phones Transform a Science Methods Course

    Science.gov (United States)

    Madden, Lauren

    2012-01-01

    A science methods instructor intentionally encouraged cell phone use for class work to discover how cell phones can be used as research tools to enhance the content and engage the students. The anecdotal evidence suggested that students who used their smartphones as research tools experienced the science content and pedagogical information…

  20. Cell-Phone Addiction: A Review

    Science.gov (United States)

    De-Sola Gutiérrez, José; Rodríguez de Fonseca, Fernando; Rubio, Gabriel

    2016-01-01

    We present a review of the studies that have been published about addiction to cell phones. We analyze the concept of cell-phone addiction as well as its prevalence, study methodologies, psychological features, and associated psychiatric comorbidities. Research in this field has generally evolved from a global view of the cell phone as a device to its analysis via applications and contents. The diversity of criteria and methodological approaches that have been used is notable, as is a certain lack of conceptual delimitation that has resulted in a broad spread of prevalent data. There is a consensus about the existence of cell-phone addiction, but the delimitation and criteria used by various researchers vary. Cell-phone addiction shows a distinct user profile that differentiates it from Internet addiction. Without evidence pointing to the influence of cultural level and socioeconomic status, the pattern of abuse is greatest among young people, primarily females. Intercultural and geographical differences have not been sufficiently studied. The problematic use of cell phones has been associated with personality variables, such as extraversion, neuroticism, self-esteem, impulsivity, self-identity, and self-image. Similarly, sleep disturbance, anxiety, stress, and, to a lesser extent, depression, which are also associated with Internet abuse, have been associated with problematic cell-phone use. In addition, the present review reveals the coexistence relationship between problematic cell-phone use and substance use such as tobacco and alcohol. PMID:27822187

  1. Health Issues: Do Cell Phones Pose a Health Hazard?

    Science.gov (United States)

    ... Procedures Home, Business, and Entertainment Products Cell Phones Health Issues Share Tweet Linkedin Pin it More sharing ... it Email Print Do cell phones pose a health hazard? Many people are concerned that cell phone ...

  2. Prevalence of Cell Phone Sharing

    OpenAIRE

    Busse, Britta; Fuchs, Marek

    2013-01-01

    With the growing mobile-only population landline telephone surveys are increasingly complemented by mobile phone interviews using a dual frame approach. Typically it is assumed that a mobile phone is a personal device solely used by one individual. Even though several articles dealt with the eventuality that several persons may be reached when calling a mobile phone number, respondent selection procedures are currently not implemented. This paper provides further insight into this phenomenon....

  3. Cell Phones: Current Research Results

    Science.gov (United States)

    ... Potential Biological or Adverse Health Effects of Wireless Communication Devices World Health Organization: Electromagnetic Fields and Public Health: Mobile Phones International Agency for Research on Cancer Press ...

  4. Hemispheric dominance and cell phone use.

    Science.gov (United States)

    Seidman, Michael D; Siegel, Bianca; Shah, Priyanka; Bowyer, Susan M

    2013-05-01

    A thorough understanding of why we hold a cell phone to a particular ear may be of importance when studying the impact of cell phone safety. To determine if there is an obvious association between sidedness of cell phone use and auditory hemispheric dominance (AHD) or language hemispheric dominance (LHD). It is known that 70% to 95% of the population are right-handed, and of these, 96% have left-brain LHD. We have observed that most people use their cell phones in their right ear. An Internet survey was e-mailed to individuals through surveymonkey.com. The survey used a modified Edinburgh Handedness Inventory protocol. Sample questions surveyed which hand was used to write with, whether the right or left ear was used for phone conversations, as well as whether a brain tumor was present. General community. An Internet survey was randomly e-mailed to 5000 individuals selected from an otology online group, patients undergoing Wada testing and functional magnetic resonance imaging, as well as persons on the university listserv, of which 717 surveys were completed. Determination of hemispheric dominance based on preferred ear for cell phone use. A total of 717 surveys were returned. Ninety percent of the respondents were right handed, and 9% were left handed. Sixty-eight percent of the right-handed people used the cell phone in their right ear, 25% in the left ear, and 7% had no preference. Seventy-two of the left-handed respondents used their left ear, 23% used their right ear, and 5% had no preference. Cell phone use averaged 540 minutes per month over the past 9 years. An association exists between hand dominance laterality of cell phone use (73%) and our ability to predict hemispheric dominance. Most right-handed people have left-brain LHD and use their cell phone in their right ear. Similarly, most left-handed people use their cell phone in their left ear. Our study suggests that AHD may differ from LHD owing to the difference in handedness and cell phone ear use

  5. Cell phone based balance trainer

    Directory of Open Access Journals (Sweden)

    Lee Beom-Chan

    2012-02-01

    Full Text Available Abstract Background In their current laboratory-based form, existing vibrotactile sensory augmentation technologies that provide cues of body motion are impractical for home-based rehabilitation use due to their size, weight, complexity, calibration procedures, cost, and fragility. Methods We have designed and developed a cell phone based vibrotactile feedback system for potential use in balance rehabilitation training in clinical and home environments. It comprises an iPhone with an embedded tri-axial linear accelerometer, custom software to estimate body tilt, a "tactor bud" accessory that plugs into the headphone jack to provide vibrotactile cues of body tilt, and a battery. Five young healthy subjects (24 ± 2.8 yrs, 3 females and 2 males and four subjects with vestibular deficits (42.25 ± 13.5 yrs, 2 females and 2 males participated in a proof-of-concept study to evaluate the effectiveness of the system. Healthy subjects used the system with eyes closed during Romberg, semi-tandem Romberg, and tandem Romberg stances. Subjects with vestibular deficits used the system with both eyes-open and eyes-closed conditions during semi-tandem Romberg stance. Vibrotactile feedback was provided when the subject exceeded either an anterior-posterior (A/P or a medial-lateral (M/L body tilt threshold. Subjects were instructed to move away from the vibration. Results The system was capable of providing real-time vibrotactile cues that informed corrective postural responses. When feedback was available, both healthy subjects and those with vestibular deficits significantly reduced their A/P or M/L RMS sway (depending on the direction of feedback, had significantly smaller elliptical area fits to their sway trajectory, spent a significantly greater mean percentage time within the no feedback zone, and showed a significantly greater A/P or M/L mean power frequency. Conclusion The results suggest that the real-time feedback provided by this system can be used

  6. The myth of cell phone radiation

    CERN Document Server

    Natarajan, Vasant

    2012-01-01

    We discuss the purported link between cell phone radiation and cancer. We show that it is inconsistent with the photoelectric effect, and that epidemiological studies of any link have no scientific basis.

  7. Bacterial ‘Cell’ Phones: Do cell phones carry potential pathogens?

    Directory of Open Access Journals (Sweden)

    Kiran Chawla

    2009-05-01

    Full Text Available Cell phones are important companions for professionals especially health care workers (HCWs for better communication in hospital. The present study compared the nature of the growth of potentially pathogenic bacterial flora on cell phones in hospital and community. 75% cell phones from both the categories grew at least one potentially pathogenic organism. Cell phones from HCWs grew significantly more potential pathogens like MRSA (20%, Acinetobacter species (5%, Pseudomonas species (2.5% as compared to the non HCWs. 97.5% HCWs use their cell phone in the hospital, 57.5% never cleaned their cell phone and 20% admitted that they did not wash their hands before or after attending patients, although majority (77.5% knows that cell phones can have harmful colonization and act as vector for nosocomial infections. It is recommended, therefore, that cell phones in the hospital should be regularly decontaminated. Moreover, utmost emphasis needs to be paid to hand washing practices among HCWs.

  8. Costly Cell Phones: The Impact of Cell Phone Rings on Academic Performance

    Science.gov (United States)

    End, Christian M.; Worthman, Shaye; Mathews, Mary Bridget; Wetterau, Katharina

    2010-01-01

    College students participated in a study on the "psychology of note taking" during which they took notes on video content and later completed a multiple-choice test on the material. Researchers assigned 71 participants to either the ringing condition (the video was disrupted by a ringing cell phone) or the control condition (no cell phone rings…

  9. Modeling cell dynamics under mobile phone radiation.

    Science.gov (United States)

    Minelli, Tullio Antonio; Balduzzo, Maurizio; Milone, Francesco Ferro; Nofrate, Valentina

    2007-04-01

    Perturbations by pulse-modulated microwave radiation from GSM mobile phones on neuron cell membrane gating and calcium oscillations have been suggested as a possible mechanism underlying activation of brain states and electroencephalographic epiphenomena. As the employ of UMTS phones seems to reveal other symptoms, a unified phenomenological framework is needed. In order to explain possible effects of mobile phone radiation on cell oscillations, GSM and UMTS low-frequency envelopes have been detected, recorded and used as input in cell models. Dynamical systems endowed with contiguous regular and chaotic regimes suitable to produce stochastic resonance can both account for the perturbation of the neuro-electrical activity and even for the low intensity of the signal perceived by high sensitive subjects. Neuron models of this kind can be employed as a reductionist hint for the mentioned phenomenology. The Hindmarsh-Rose model exhibits frequency enhancement and regularization phenomena induced by weak GSM and UMTS. More realistic simulations of cell membrane gating and calcium oscillations have been performed with the help of an adaptation of the Chay-Keizer dynamical system. This scheme can explain the suspected subjective sensitivity to mobile phone signals under the thermal threshold, in terms of cell calcium regularity mechanisms. Concerning the two kinds of emission, the stronger occupation of the ELF band of last generation UMTS phones is compensated by lower power emitted.

  10. Cell Phoning and Texting While Driving

    Directory of Open Access Journals (Sweden)

    Judy Honoria Rosaire Telemaque

    2015-07-01

    Full Text Available A qualitative phenomenological study was conducted on the consequences of cell phone use while operating a vehicle. We discussed why talking and texting on cell phones are so popular through the analysis of our interviews with police officers, driving instructors, and parents of teens and young adults. The participants came from central, northeastern, northwestern, and southeastern Connecticut. All had exposure with respect to the effects of cell phone usage problem. The study reached a point of theoretical saturation or redundancy by which the analysis no longer resulted in new themes. We concluded that the discoveries revealed the necessity for education, expansion of technology, and additional driver education preparation, which may provide a path for leadership to help solve the problem.

  11. Smart Bengali Cell Phone Keypad Layout

    CERN Document Server

    Azad, Md Abul Kalam; Ahmad, Shabbir; Kamruzzaman, S M

    2010-01-01

    Nowadays cell phone is the most common communicating used by mass people. SMS based communication is a cheap and popular communication method. It is human tendency to have the opportunity to write SMS in their mother language. Text input in mother language is more flexible when the alphabets of that language are printed on the keypad. Bangla mobile keypad based on phonetics has been proposed earlier. But the keypad is not scientific from frequency and flexibility point of view. Since it is not a feasible solution in this paper we have proposed an efficient Bengali keypad for cell phone and other cellular device. The proposed keypad is based on the frequency of the alphabets in Bengali language and also with the view of structure of human finger movements. We took the two points in count to provide a flexible and fast cell phone keypad.

  12. [Cell phones: health risks and prevention].

    Science.gov (United States)

    Talamanca, I Figà; Giliberti, C; Salerno, S

    2012-01-01

    The paper describes first of all the electromagnetic radiation of cellular phones and presents the physical parameters used to measure and evaluate the absorption of emissions of radio stations and cellular phones. It then presents selected research results of the experimental studies in vivo and in vitro which examine the biological effects of the emissions of cellular phones. The review of the epidemiologic evidence focuses in particular the epidemiologic studies on the use of cell phones and brain tumours, identifying some of the reasons of the conflicting results obtained. Studies dealing with the health risks involved in the increasing use of cellular phones by adolescents and children, more sensitive to this exposure, are also presented showing the need for special caution. The problem of hypersensitivity observed in some individuals is also briefly discussed. Finally the paper presents a summary of the main prevention measures necessary in order to reduce the risks in the framework of the "precautionary principle" including prevention policies and exposure limits in various countries.

  13. Breaking alibis through cell phone mapping

    CSIR Research Space (South Africa)

    Schmitz, Peter MU

    2000-01-01

    Full Text Available in support of the prosecution was a powerful and persuasive device. Subsequently, another prosecutor has contacted CSIR to map data for a case involving two murders in which cell phones were also used during the commission of the crimes....

  14. Cell Phones in the Classroom: Are We Dialing up Disaster?

    Science.gov (United States)

    Engel, George; Green, Tim

    2011-01-01

    Over the last decade there has been a rapid diffusion of cellular technology. Though cell phone use began as a business tool, it has now become part of popular culture. Because of the near ubiquitous presence of cell phone technology among teens in the United States, schools are beginning to explore the use of cell phones as a learning tool. This…

  15. Cell Phones in the Classroom: Preservice Teachers' Perceptions

    Science.gov (United States)

    Thomas, Kevin; O'Bannon, Blanche

    2013-01-01

    This study employed a survey to examine the perceptions of 92 preservice teachers enrolled at a small Midwestern liberal arts university regarding their support of the use of cell phones in the classroom, the benefits of specific cell phone features for school-related work, and the instructional benefits of and barriers to using cell phones in the…

  16. Cell Phones in the Classroom: Are We Dialing up Disaster?

    Science.gov (United States)

    Engel, George; Green, Tim

    2011-01-01

    Over the last decade there has been a rapid diffusion of cellular technology. Though cell phone use began as a business tool, it has now become part of popular culture. Because of the near ubiquitous presence of cell phone technology among teens in the United States, schools are beginning to explore the use of cell phones as a learning tool. This…

  17. Cell Phones in the Classroom: Preservice Teachers' Perceptions

    Science.gov (United States)

    Thomas, Kevin; O'Bannon, Blanche

    2013-01-01

    This study employed a survey to examine the perceptions of 92 preservice teachers enrolled at a small Midwestern liberal arts university regarding their support of the use of cell phones in the classroom, the benefits of specific cell phone features for school-related work, and the instructional benefits of and barriers to using cell phones in the…

  18. Accidental cell phone ingestion with pharyngeal impaction.

    Science.gov (United States)

    Ali, Mohammed M; Bahl, Kazal; Dross, Matthew; Farooqui, Shoheb; Dross, Peter

    2014-09-01

    35 year old intoxicated male ingested an unusual, large foreign object (cell phone). To report the ingestion of an unusual large foreign object with hypopharyngeal impaction, complications, and treatment. Foreign body ingestion in the adult population is more prevalent in those who engage in drug or alcohol abuse. Impaction and perforation of the upper aerodigestive tract can lead to significant and potentially fatal complications including parapharyngeal/retropharyngeal abscess, mediastinitis, and aortoesophageal fistula. The treatment of foreign object ingestion is dependent on the type of foreign object ingested, its location, and potential for perforation. Endoscopic removal under general anesthesia is the treatment method recommended for foreign bodies impacted at the cricopharyngeus or esophagus. We report the only case of the accidental ingestion of an entire cell phone with casing. A plain film x-ray of the neck can be used in the assessment of the location of radiopaque foreign objects and in diagnosing potential complication.

  19. Video Field Studies with your Cell Phone

    DEFF Research Database (Denmark)

    Buur, Jacob; Fraser, Euan

    2010-01-01

    is monumental, that equipment is difficult to handle etc. This tutorial presents a lightweight entry into video field studies, using cheap devices like cell phones and portable webcams for informal shooting and simple computer handling for editing. E.g. how far can you get with an iPhone or a video capable i......, and in particular practitioners from smaller organizations are understandably nervous about embarking on video projects out of fear that it is difficult to get consent in the first place, that the ethics is difficult to handle, that video shooting makes the social relations awkward, that the editing task......Pod? Or with the GoPRO sports camera? Our approach has a strong focus on how to use video in design, rather than on the technical side. The goal is to engage design teams in meaningful discussions based on user empathy, rather than to produce beautiful videos. Basically it is a search for a minimalist way...

  20. Work productivity in rhinitis using cell phones

    DEFF Research Database (Denmark)

    Bousquet, J.; Bewick, Bridgette M; Arnavielhe, S

    2017-01-01

    Allergic rhinitis often impairs social life and performance. The aim of this cross-sectional study was to use cell phone data to assess the impact on work productivity of uncontrolled rhinitis assessed by visual analogue scale (VAS). A mobile phone app (Allergy Diary, Google Play Store and Apple...... App Store) collects data from daily visual analogue scales (VAS) for overall allergic symptoms (VAS-global measured), nasal (VAS-nasal), ocular (VAS-ocular) and asthma symptoms (VAS-asthma) as well as work (VAS-work). A combined nasal-ocular score is calculated. The Allergy Diary is available in 21...... countries. The app includes the Work Productivity and Activity Impairment Allergic Specific Questionnaire (WPAI:AS) in six EU countries. All consecutive users who completed the VAS-work from 1 June to 31 October 2016 were included in the study. A total of 1136 users filled in 5818 days of VAS-work. Symptoms...

  1. Distracted pedestrian sustains orbital fracture while on cell phone

    Directory of Open Access Journals (Sweden)

    Edell AR

    2013-04-01

    Full Text Available Aimée R Edell, Jesse J Jung, Joel M Solomon, Richard N Palu Department of Ophthalmology, New York University School of Medicine, New York, NY, USA Abstract: Use of cell phones in the general population has become increasingly commonplace. The distracting effects of cell phones among automobile drivers are well established, and legislation prohibits the use of handheld cell phones while driving in several states. Recent research has focused on the similar distracting effects of cell phones in the pedestrian population. In this report, an older gentleman suffered extensive facial trauma requiring surgery as a direct effect of cell phone use at the time the trauma occurred. This case highlights the role that portable electronic devices can play as a cause of ocular trauma. Keywords: orbital fracture, ocular trauma, orbital floor fracture, cell phone distraction, pedestrian safety

  2. Discovering urban activity patterns in cell phone data

    OpenAIRE

    Widhalm, Peter; Yang, Yingxiang; Ulm, Michael; Athavale, Shounak; Gonzalez, Marta C.

    2015-01-01

    Massive and passive data such as cell phone traces provide samples of the whereabouts and movements of individuals. These are a potential source of information for models of daily activities in a city. The main challenge is that phone traces have low spatial precision and are sparsely sampled in time, which requires a precise set of techniques for mining hidden valuable information they contain. Here we propose a method to reveal activity patterns that emerge from cell phone data by analyzing...

  3. Thermal plasma treatment of cell-phone waste : preliminary result

    Energy Technology Data Exchange (ETDEWEB)

    Ruj, B. [Central Mechanical Engineering Research Inst., Durgapur (India). Thermal Engineering Group; Chang, J.S.; Li, O.L. [McMaster Univ., Hamilton, ON (Canada). Dept. of Engineering Physics; Pietsch, G. [RWTH Aachen Univ., Aachen (Germany)

    2010-07-01

    The cell phone is an indispensable service facilitator, however, the disposal and recycling of cell phones is a major problem. While the potential life span of a mobile phone, excluding batteries, is over 10 years, most of the users upgrade their phones approximately four times during this period. Cell phone waste is significantly more hazardous than many other municipal wastes as it contains thousands of components made of toxic chemicals and metals like lead, cadmium, chromium, mercury, polyvinyl chlorides (PVC), brominated flame retardants, beryllium, antimony and phthalates. Cell phones also use many expensive rare metals. Since cell phones are made up of plastics, metals, ceramics, and trace other substances, primitive recycling or disposal of cell phone waste to landfills and incinerators creates irreversible environmental damage by polluting water and soil, and contaminating air. In order to minimize releases into the environment and threat to human health, the disposal of cell phones needs to be managed in an environmentally friendly way. This paper discussed a safer method of reducing the generation of syngas and hydrocarbons and metal recovery through the treatment of cell phone wastes by a thermal plasma. The presentation discussed the experiment, with particular reference to sample preparation; experimental set-up; and results four samples with different experimental conditions. It was concluded that the plasma treatment of cell phone waste in reduced condition generates gaseous components such as hydrogen, carbon monoxide, and hydrocarbons which are combustible. Therefore, this system is an energy recovery system that contributes to resource conservation and reduction of climate change gases. 5 refs., 2 tabs., 2 figs.

  4. Using cell phones to improve language skills: the Hadeda project

    CSIR Research Space (South Africa)

    Butgereit, L

    2009-12-01

    Full Text Available , teenagers, and young adults. Hadeda is a facility where teachers and parents can create spelling lists for pupils and children using either a cell phone or an internet based workstation. Hadeda then generates a fun and enjoyable cell phone midlet (computer...

  5. Cell Phones: A Bibliometric Analysis Related to Business Students

    Science.gov (United States)

    Piotrowski, Chris

    2014-01-01

    Recent reviews of the literature indicate that the scope of research on cell or mobile phones covers a vast typology (Piotrowski & Kass, 2013). The majority of this research is concentrated in the technology, education, and social sciences fields. However, there is a dearth of bibliometric studies on cell phones related to business. To that…

  6. Cell Phones: Business Students in the Business Literature

    Science.gov (United States)

    Piotrowski, Chris

    2013-01-01

    Research on the topic of cell phones has proliferated over the past decade. Based on a review of the literature, it appears that the majority of the extant research on the topic resides in the technology, education, and social sciences fields. Recent reviews indicate that the scope of the research on cell/mobile phones is eclectic in nature…

  7. Maternal cell phone and cordless phone use during pregnancy and behaviour problems in 5-year-old children

    NARCIS (Netherlands)

    Guxens, Monica; van Eijsden, Manon; Vermeulen, Roel; Loomans, Eva; Vrijkotte, Tanja G. M.; Komhout, Hans; van Strien, Rob T.; Huss, Anke

    2013-01-01

    Background A previous study found an association between maternal cell phone use during pregnancy and maternal-reported child behaviour problems at age 7. Together with cell phones, cordless phones represent the main exposure source of radiofrequency-electromagnetic fields to the head. Therefore, we

  8. The Relationship between Cell Phone Use and Identity Theft

    Science.gov (United States)

    Saunders, Lewis O.

    2014-01-01

    The growth of mobile phone use has paralleled increased reports of identity theft. Identity theft can result in financial loss and threats to a victim's personal safety. Although trends in identity theft are well-known, less is known about individual cell phone users' attitudes toward identity theft and the extent to which they connect it to cell…

  9. Micronucleus frequency in buccal mucosa cells of mobile phone users.

    Science.gov (United States)

    Hintzsche, Henning; Stopper, Helga

    2010-03-01

    Mobile phones are being used extensively throughout the world, with more than four billion accounts existing in 2009. This technology applies electromagnetic radiation in the microwave range. Health effects of this radiation have been subject of debate for a long time, both within the scientific community and within the general public. This study investigated the effect of mobile phone use on genomic instability of the human oral cavity's mucosa cells. 131 Individuals donated buccal mucosa cells extracted by slightly scraping the oral cavity with a cotton swab. Every participant filled out a questionnaire about mobile phone use including duration of weekly use, overall period of exposure and headset usage. 13 Individuals did not use mobile phones at all, 85 reported using the mobile phone for three hours per week or less, and 33 reported use of more than three hours per week. Additionally, information on age, gender, body weight, smoking status, medication and nutrition was retrieved. For staining of the cells a procedure using alpha-tubulin-antibody and chromomycin A(3) was applied. Micronuclei and other markers were evaluated in 1000 cells per individual at the microscope. A second scorer counted another 1000 cells, resulting in 2000 analyzed cells per individual. Mobile phone use did not lead to a significantly increased frequency of micronuclei.

  10. Observing Cell Phone Use and Enhancing Collaborative Learning Using a Wiki

    Science.gov (United States)

    Tolman, Elizabeth G.

    2013-01-01

    Cell phone use is evident in society. Individuals have cell phone conversations while waiting in line at the grocery store, glance at their cell phones during meetings, check Facebook while having dinner with friends, have a meaningful phone conversation with a parent, and even text while sitting in church service. This assignment provides…

  11. Cell Phone Use and Child and Adolescent Reading Proficiency.

    Science.gov (United States)

    Hofferth, Sandra L; Moon, Ui Jeong

    2012-04-01

    This study examined the association between cell phone use, including minutes spent talking and number of text messages sent, and two measures of children's reading proficiency - tests of word decoding and reading comprehension - in the United States. Data were drawn from the Child Development Supplement to the Panel Study of Income Dynamics, a nationally representative survey of 1,147 children 10-18 in 2009. Children whose parents were better educated, who had higher family incomes, who had fewer siblings, and who lived in urban areas were more likely to own or share a cell phone. Among those with access to a phone, children who spent more time talking on the phone were less proficient at word decoding, whereas children who spent more time sending text messages had greater reading comprehension. Although girls spent more time texting than did boys, there were no gender differences in the association between time spent talking or number of text messages sent with achievement. In spite of racial/ethnic differences in cell phone use levels, there were no racial/ethnic differences in the association between cell phone use and reading proficiency.

  12. I 5683 you: dialing phone numbers on cell phones activates key-concordant concepts.

    Science.gov (United States)

    Topolinski, Sascha

    2011-03-01

    When people perform actions, effects associated with the actions are activated mentally, even if those effects are not apparent. This study tested whether sequences of simulations of virtual action effects can be integrated into a meaning of their own. Cell phones were used to test this hypothesis because pressing a key on a phone is habitually associated with both digits (dialing numbers) and letters (typing text messages). In Experiment 1, dialing digit sequences induced the meaning of words that share the same key sequence (e.g., 5683, LOVE). This occurred even though the letters were not labeled on the keypad, and participants were not aware of the digit-letter correspondences. In Experiment 2, subjects preferred dialing numbers implying positive words (e.g., 37326, DREAM) over dialing numbers implying negative words (e.g., 75463, SLIME). In Experiment 3, subjects preferred companies with phone numbers implying a company-related word (e.g., LOVE for a dating agency, CORPSE for a mortician) compared with companies with phone numbers implying a company-unrelated word.

  13. Mobile cell-phones (M-phones in telemicroscopy: increasing connectivity of isolated laboratories

    Directory of Open Access Journals (Sweden)

    Missoni Eduardo

    2009-06-01

    Full Text Available Abstract Background The development of modern information telecommunication (ITC technology and its use in telemedicine plays an increasingly important role in facilitating access to some diagnostic services even to people living in the most remote areas. However, physical and economical constraints in the access to broad band data-transmission network, still represent a considerable obstacle to the transmission of images for the purpose of tele-pathology. Methods Indifferently using m-phones of different brands, and a variety of microscopic preparations, images were taken without the use of any adaptor simply approaching the lens of the mobile cell phone camera to the ocular of common optical microscopes, and subsequently sent via Multimedia Messaging Services (MMS to distant reference centres for tele-diagnosis. Access to MMS service was reviewed with specific reference to the African information communication technology (ICT market. Results Images of any pathologic preparation could be captured and sent over the mobile phone with an MMS, without being limited by appropriate access to the internet for transmission (i.e. access to broad-band services. The quality of the image was not influenced by the brand or model of the mobile-phone used, but only by its digital resolution, with any resolution above 0.8 megapixel resulting in images sufficient for diagnosis. Access to MMS services is increasingly reaching remote disadvantaged areas. Current penetration of the service in Africa was mapped appearing already available in almost every country, with penetration index varying from 1.5% to 92.2%. Conclusion The use of otherwise already widely available technologies, without any need for adaptors or otherwise additional technology, could significantly increase opportunities and quality diagnostics while lowering costs and considerably increasing connectivity between most isolated laboratories and distant reference center.

  14. The dimensions of brand romance as predictors of brand loyalty among cell phone users

    National Research Council Canada - National Science Library

    Danie Petzer; Pierre Mostert; Liezl-Marie Kruger; Stefanie Kuhn

    2014-01-01

      In a competitive cell phone industry where consumers have a wide variety of cell phone brands to choose from, it is imperative for marketers to foster brand loyalty in order to establish enduring...

  15. Leucocytes, cytokines and satellite cells

    DEFF Research Database (Denmark)

    Paulsen, Gøran; Mikkelsen, Ulla Ramer; Raastad, Truls

    2012-01-01

    -damaging exercise', primarily eccentric exercise. We review the evidence for the notion that the degree of muscle damage is related to the magnitude of the cytokine response. In the third and final section, we look at the satellite cell response to a single bout of eccentric exercise, as well as the role...... damage. With the exception of IL-6, the sources of systemic cytokines following exercise remain unclear The satellite cell response to severe muscle damage is related to regeneration, whereas the biological significance of satellite cell proliferation after mild damage or non-damaging exercise remains...

  16. Cell Phones + Self-Access: A Summer Campaign

    Directory of Open Access Journals (Sweden)

    Kirsten Mashinter

    2011-09-01

    Full Text Available This is a summary of a project whereby the author developed a summer vacation contest for the SAC in which students could participate regardless of their physical distance from the facility. This contest was centered on cell phones, photography, and writing and was platformed online.

  17. Internet and Cell Phone Based Smoking Cessation Programs among Adolescents

    Science.gov (United States)

    Mehta, Purvi; Sharma, Manoj

    2010-01-01

    Smoking cessation among adolescents is a salient public health issue, as it can prevent the adoption of risky health behaviors and reduce negative impacts on health. Self-efficacy, household and social support systems, and perceived benefits are some important cessation determinants. With the popular use of the Internet and cell phone usage among…

  18. Design Principles for Cell Phone Learning in EFL

    Science.gov (United States)

    Wang, Feihong

    2010-01-01

    Cell phone learning (C-learning), as an instructional approach, has been gaining more and more attention in the field of teaching English as a foreign language (EFL) in the last 10 years. While studies have proved C-learning an effective instructional approach in research settings, a review of literature indicates the lack of design principles to…

  19. Cell Phone Use by Adolescents with Asperger Syndrome

    Science.gov (United States)

    Durkin, Kevin; Whitehouse, Andrew; Jaquet, Emma; Ziatas, Kathy; Walker, Allan J.

    2010-01-01

    While young people have generally been at the forefront of the adoption and use of new communications technologies, little is known of uses by exceptional youth. This study compares cell phone use by a group of adolescents with Asperger Syndrome (n = 35) with that by a group of adolescents with typical development (n = 35). People with Asperger…

  20. Using technology to promote mobile learning: engaging students with cell phones in the classroom.

    Science.gov (United States)

    Robb, Meigan; Shellenbarger, Teresa

    2012-01-01

    Advancements in cell phone technology have impacted every aspect of society. Individuals have instant access to social networks, Web sites, and applications. Faculty need to consider using these mobile devices to enrich the classroom. The authors discuss how they successfully designed and incorporated cell phone learning activities into their classrooms. Teaching-learning strategies using cell phone technology and recommendations for overcoming challenges associated with cell phone use in the classroom are discussed.

  1. No Evidence Linking Cell Phone Use to Risk of Brain Tumors

    Science.gov (United States)

    ... Cell Phone Study Health Issues Current Research Results Children and Cell Phones The Line On Cell Phones (video) - Page Last Updated: 07/25/2015 Note: If you need help accessing information in different file formats, see Instructions for Downloading Viewers and Players . Language Assistance Available: ...

  2. Cell Phones in the Classroom: Teachers' Perspectives of Inclusion, Benefits, and Barriers

    Science.gov (United States)

    Thomas, Kevin M.; O'Bannon, Blanche W.; Bolton, Natalie

    2013-01-01

    Historically viewed as a disruption by teachers, cell phones have been banned from 69% of classrooms (Common Sense Media, 2009). The increased ubiquity and instructional features of cell phones have prompted some teachers to re-evaluate the ban and consider the benefits associated with allowing cell phones in the classroom. This study surveyed 79…

  3. Cell Phones in the Classroom: Teachers' Perspectives of Inclusion, Benefits, and Barriers

    Science.gov (United States)

    Thomas, Kevin M.; O'Bannon, Blanche W.; Bolton, Natalie

    2013-01-01

    Historically viewed as a disruption by teachers, cell phones have been banned from 69% of classrooms (Common Sense Media, 2009). The increased ubiquity and instructional features of cell phones have prompted some teachers to re-evaluate the ban and consider the benefits associated with allowing cell phones in the classroom. This study surveyed 79…

  4. College Students' Cell Phone Use, Beliefs, and Effects on Their Learning

    Science.gov (United States)

    Elder, Anastasia D.

    2013-01-01

    The purpose of this study is to explore college students' self-reported cell phone use and beliefs and investigate the effect on student learning. Eighty-eight college students responded to a questionnaire about their use of cell phones during classes, studying, and driving and about their beliefs about how cell phones impact their schoolwork. In…

  5. 78 FR 27441 - NIJ Evaluation of Hand-Held Cell Phone Detector Devices

    Science.gov (United States)

    2013-05-10

    ... of Justice Programs NIJ Evaluation of Hand-Held Cell Phone Detector Devices AGENCY: National...) is soliciting interest in supplying hand-held cell phone detector devices for participation in an... soliciting interest in supplying hand-held cell phone detector devices for participation in an evaluation...

  6. A Happy and Engaged Class without Cell Phones? It's Easier than You Think

    Science.gov (United States)

    Katz, Louise; Lambert, Warren

    2016-01-01

    Although there have been many suggestions for incorporating cell phone use into classroom activities, there have been few suggestions for removing cell phone use from the classroom. This article presents an easy-to-implement method using positive reinforcement that effectively removes cell phones from the classroom in a way that is highly endorsed…

  7. Cell Phones in the Classroom: Teachers' Perspectives of Inclusion, Benefits, and Barriers

    Science.gov (United States)

    Thomas, Kevin M.; O'Bannon, Blanche W.; Bolton, Natalie

    2013-01-01

    Historically viewed as a disruption by teachers, cell phones have been banned from 69% of classrooms (Common Sense Media, 2009). The increased ubiquity and instructional features of cell phones have prompted some teachers to re-evaluate the ban and consider the benefits associated with allowing cell phones in the classroom. This study surveyed 79…

  8. The outcome of dimethylglyoxime testing in a sample of cell phones in Denmark

    DEFF Research Database (Denmark)

    Thyssen, J.P.; Johansen, J.D.; Zachariae, C.;

    2008-01-01

    Background: Nickel dermatitis may be caused by frequent and prolonged use of cell phones. Because little is known about the frequency of nickel release from cell phones, it is difficult to estimate the risk of nickel sensitization and dermatitis among their users. Objective: Inspired by a recent...... case of nickel dermatitis from prolonged cell phone use, the frequency of dimethylglyoxime (DMG)-positive cell phones on the Danish market was investigated. Methods: Five major cell phone companies were contacted. Two were visited, and the DMG test was performed on a sample of their products. Results......: 5 of 15 (33.3%) phones from company A and 3 of 26 (11.5%) phones from company B showed at least 1 positive reaction. 3 phones had more than 1 positive DMG spots. Conclusions: This study documents that excessive nickel release (i.e. a positive DMG test) is relatively frequent in a sample of cell...

  9. Effects of Classroom Cell Phone Use on Expected and Actual Learning

    Science.gov (United States)

    Froese, Arnold D.; Carpenter, Christina N.; Inman, Denyse A.; Schooley, Jessica R.; Barnes, Rebecca B.; Brecht, Paul W.; Chacon, Jasmin D.

    2012-01-01

    Studies of driving indicate that the conversational aspects of using cell phones generate high risks from divided attention. Prior surveys document high rates at which students carry phones to and use them during class. Some experiments have demonstrated that cell phones distract students from learning. The present studies combined survey and…

  10. AUTOMATED SYSTEM FOR CELL PHONES PRECISE DIRECTION FINDING

    Directory of Open Access Journals (Sweden)

    H. M. Gadzhiev

    2016-01-01

    Full Text Available It is proved that the navigation system use for direction finding of cell phones will greatly expand the functionality and services of telephone networks mobile operators. The direction-finding system advantages and creation of automated system of direction finding cell phones proposed, which significantly expand the possibilities of services of operators of cellular communication in the cell using standard computer equipment operators themselves have been revelead. The developed system has a modular design, which allows modifying software packages, expanding the functionality. The procedure and algorithm of direction finding, allowing piecewise linear approximation of the graph of the displacement of each subscriber is outlined. The developed direction-finding system application for statistical information and optimization of urban public services processing, choice of speed, route and other activities improving the quality of human life is proposed.

  11. Cell-phone-based platform for biomedical device development and education applications

    National Research Council Canada - National Science Library

    Smith, Zachary J; Chu, Kaiqin; Espenson, Alyssa R; Rahimzadeh, Mehdi; Gryshuk, Amy; Molinaro, Marco; Dwyre, Denis M; Lane, Stephen; Matthews, Dennis; Wachsmann-Hogiu, Sebastian

    2011-01-01

    In this paper we report the development of two attachments to a commercial cell phone that transform the phone's integrated lens and image sensor into a 350x microscope and visible-light spectrometer...

  12. Lack of Parental Rules for Cell Phone Use among Low Income Mexican Descendent Adolescents

    Directory of Open Access Journals (Sweden)

    Christine Bracamonte Wiggs

    2013-12-01

    Full Text Available Youth have access to and utilize various types of technology at a growing rate. Cell phones are a portable way for adolescents to remain in constant contact with friends, parents, and others. While White youth are more likely to have a cell phone compared to Latino youth, the trends for cell phone use are similar among all teens with text messaging serving as the most popular means of communication. Despite their high volume of communication with others via cell phones, adolescents are likely to have little or no adult supervision while using technology. With a lack of parental supervision or awareness regarding youth technology use, adolescents may be especially vulnerable to cyberbullying and other negative health impacts. The current study investigates cell phone and texting use among a community sample of Latino adolescents and examines how parental rules regarding cell phone use influences adolescents’ cell phone and texting behaviors.

  13. Cell-Phone Use and Self-Reported Hypertension: National Health Interview Survey 2008

    Directory of Open Access Journals (Sweden)

    Sivaranjani Suresh

    2011-01-01

    Results. 43.5% of the participants were cell-phone nonusers, while 13.8% were predominantly cell-phone users. We found that cell-phone use was inversely associated with hypertension, independent of age, sex, race/ethnicity, smoking, alcohol consumption, education, body mass index (BMI, and physical activity. Compared to cell-phone nonusers, the multivariable odds ratio (95% confidence interval of hypertension was 0.86 (0.75–0.98, P trend  =  .005 among predominantly cell-phone users. This inverse association between cell-phone use and hypertension was stronger in women, those aged <60 years, whites, and those with BMI <25 kg/m2. Conclusion. We found that cell-phone usage was protectively associated with self-reported hypertension in a nationally representative sample of US adults.

  14. Cell phones: a digital cartography of São Paulo

    Directory of Open Access Journals (Sweden)

    Polise Moreira De Marchi

    2014-01-01

    Full Text Available The fundamental function of maps has always been to understand, interpret, and represent the world. Therefore, maps have a communication role, as a language. As communication tool, maps spatialize the interaction of social, economic and cultural urban realities in a graphic expression that provides the very meaning of urban systems. The aim of this paper is to report an academic study involving digital interface design graduate students. They investigated the role of locative media as potential instruments for registering and mapping experiences, observations and perceptions of urban life. This study considers that students can stimulate interactions across the city, whether, directly, in its physical space or, indirectly, through interfaces such as cell phone applications. The project also sought to discuss the cell phone as a producer of new languages, since instead of being merely a telephone it combines the functions of different media and can produce images, videos, sounds etc.

  15. NMR imaging of cell phone radiation absorption in brain tissue.

    Science.gov (United States)

    Gultekin, David H; Moeller, Lothar

    2013-01-02

    A method is described for measuring absorbed electromagnetic energy radiated from cell phone antennae into ex vivo brain tissue. NMR images the 3D thermal dynamics inside ex vivo bovine brain tissue and equivalent gel under exposure to power and irradiation time-varying radio frequency (RF) fields. The absorbed RF energy in brain tissue converts into Joule heat and affects the nuclear magnetic shielding and the Larmor precession. The resultant temperature increase is measured by the resonance frequency shift of hydrogen protons in brain tissue. This proposed application of NMR thermometry offers sufficient spatial and temporal resolution to characterize the hot spots from absorbed cell phone radiation in aqueous media and biological tissues. Specific absorption rate measurements averaged over 1 mg and 10 s in the brain tissue cover the total absorption volume. Reference measurements with fiber optic temperature sensors confirm the accuracy of the NMR thermometry.

  16. Self-Contained Thermoelectric Generator for Cell Phones

    Science.gov (United States)

    Anatychuk, L. I.; Mykhailovsky, V. Ya.; Strutynska, L. T.

    2011-05-01

    Results of research and development of a 1 W thermoelectric generator for cell phones are presented. A physical model of the generator with catalytic combustion of gas fuel is proposed. A computer simulation method is used to determine the optimal parameters of the thermopile, catalytic heat source, and microgenerator heat rejection system whereby the efficiency of gas combustion heat conversion into electrical energy is a factor of two higher compared with existing analogs. The generator design is described, and results of experimental research on its parameters and the charging rate of cell phone batteries with capacity of 900 mA h to 1600 mA h are given. In the self-contained operating mode of various low-power devices, the elaborated thermoelectric generator with a catalytic heat source is an alternative to traditional sources of chemical energy.

  17. NMR imaging of cell phone radiation absorption in brain tissue

    OpenAIRE

    Gultekin, David H.; Moeller, Lothar

    2012-01-01

    A method is described for measuring absorbed electromagnetic energy radiated from cell phone antennae into ex vivo brain tissue. NMR images the 3D thermal dynamics inside ex vivo bovine brain tissue and equivalent gel under exposure to power and irradiation time-varying radio frequency (RF) fields. The absorbed RF energy in brain tissue converts into Joule heat and affects the nuclear magnetic shielding and the Larmor precession. The resultant temperature increase is measured by the resonance...

  18. Tinnitus and cell phones: the role of electromagnetic radiofrequency radiation

    OpenAIRE

    Seyed Mohammad Javad Mortazavi; Seyed Ali Reza Mortazavi

    2016-01-01

    ABSTRACT INTRODUCTION: Tinnitus is a multifactorial condition and its prevalence has increased on the past decades. The worldwide progressive increase of the use of cell phones has exposed the peripheral auditory pathways to a higher dose of electromagnetic radiofrequency radiation (EMRFR). Some tinnitus patients report that the abusive use of mobiles, especially when repeated in the same ear, might worsen ipsilateral tinnitus. OBJECTIVE: The aim of this study was to evaluate the availabl...

  19. Online camera-gyroscope autocalibration for cell phones.

    Science.gov (United States)

    Jia, Chao; Evans, Brian L

    2014-12-01

    The gyroscope is playing a key role in helping estimate 3D camera rotation for various vision applications on cell phones, including video stabilization and feature tracking. Successful fusion of gyroscope and camera data requires that the camera, gyroscope, and their relative pose to be calibrated. In addition, the timestamps of gyroscope readings and video frames are usually not well synchronized. Previous paper performed camera-gyroscope calibration and synchronization offline after the entire video sequence has been captured with restrictions on the camera motion, which is unnecessarily restrictive for everyday users to run apps that directly use the gyroscope. In this paper, we propose an online method that estimates all the necessary parameters, whereas a user is capturing video. Our contributions are: 1) simultaneous online camera self-calibration and camera-gyroscope calibration based on an implicit extended Kalman filter and 2) generalization of the multiple-view coplanarity constraint on camera rotation in a rolling shutter camera model for cell phones. The proposed method is able to estimate the needed calibration and synchronization parameters online with all kinds of camera motion and can be embedded in gyro-aided applications, such as video stabilization and feature tracking. Both Monte Carlo simulation and cell phone experiments show that the proposed online calibration and synchronization method converge fast to the ground truth values.

  20. Satellite cells: the architects of skeletal muscle.

    Science.gov (United States)

    Chang, Natasha C; Rudnicki, Michael A

    2014-01-01

    The outstanding regenerative capacity of skeletal muscle is attributed to the resident muscle stem cell termed satellite cell. Satellite cells are essential for skeletal muscle regeneration as they ultimately provide the myogenic precursors that rebuild damaged muscle tissue. Satellite cells characteristically are a heterogeneous population of stem cells and committed progenitor cells. Delineation of cellular hierarchy and understanding how lineage fate choices are determined within the satellite cell population will be invaluable for the advancement of muscle regenerative therapies.

  1. Teaching the Fundamentals of Cell Phones and Wireless Communications

    Science.gov (United States)

    Davids, Mark; Forrest, Rick; Pata, Don

    2010-04-01

    Wireless communications are ubiquitous. Students and teachers use iPhones®, BlackBerrys®, and other smart phones at home and at work. More than 275 million Americans had cell phones in June of 2009 and expanded access to broadband is predicted this year.2 Despite the plethora of users, most students and teachers do not understand "how they work." Over the past several years, three high school teachers have collaborated with engineers at Cingular, Motorola, and the University of Michigan to explore the underlying science and design a three-week, student-centered unit with a constructivist pedagogy consistent with the "Modeling in Physics" philosophy.3 This unique pilot program reinforces traditional physics topics including vibrations and waves, sound, light, electricity and magnetism, and also introduces key concepts in communications and information theory. This article will describe the motivation for our work, outline a few key concepts with the corresponding student activities, and provide a summary of the program that has been developed to engage and inspire the next generation of scientists, engineers, and citizens.

  2. Tinnitus and cell phones: the role of electromagnetic radiofrequency radiation

    Directory of Open Access Journals (Sweden)

    Luisa Nascimento Medeiros

    2016-02-01

    Full Text Available ABSTRACT INTRODUCTION: Tinnitus is a multifactorial condition and its prevalence has increased on the past decades. The worldwide progressive increase of the use of cell phones has exposed the peripheral auditory pathways to a higher dose of electromagnetic radiofrequency radiation (EMRFR. Some tinnitus patients report that the abusive use of mobiles, especially when repeated in the same ear, might worsen ipsilateral tinnitus. OBJECTIVE: The aim of this study was to evaluate the available evidence about the possible causal association between tinnitus and exposure to electromagnetic waves. METHODS: A literature review was performed searching for the following keywords: tinnitus, electromagnetic field, mobile phones, radio frequency, and electromagnetic hypersensitivity. We selected 165 articles that were considered clinically relevant in at least one of the subjects. RESULTS: EMRFR can penetrate exposed tissues and safety exposure levels have been established. These waves provoke proved thermogenic effects and potential biological and genotoxic effects. Some individuals are more sensitive to electromagnetic exposure (electrosensitivity, and thus, present earlier symptoms. There may be a common pathophysiology between this electrosensitivity and tinnitus. CONCLUSION: There are already reasonable evidences to suggest caution for using mobile phones to prevent auditory damage and the onset or worsening of tinnitus.

  3. 77 FR 22331 - Submission for OMB Review; Comment Request; Solar Cell: A Mobile UV Manager for Smart Phones...

    Science.gov (United States)

    2012-04-13

    ... Mobile UV Manager for Smart Phones Phase II (NCI) Summary: Under the provisions of Section 3507(a)(1)(D...: Title: Solar Cell: A Mobile UV Manager for Smart Phones Phase II (NCI). Type of Information Collection... phone application, Solar Cell, which uses smart phone technology to aid users in protecting their skin...

  4. A study on some psychological health effects of cell-phone usage amongst college going students

    OpenAIRE

    Jayanti P Acharya, Indranil Acharya, Divya Waghrey

    2013-01-01

    Cell phones have come to stay. Their use without any knowledge of their harmful effects like cancers and other health effects is not ‘quite’ safe. Studies on cancers due to electromagnetic radiations from cell phones are available but there is a need to research on the detrimental physical and psychological effects esp. on rampant users like college-goers. This study focused on certain psychological or mental health effects of cell phone usage amongst students pursuing professional courses in...

  5. Cell phone ringtone, but not landline phone ringtone, affects complex reaction time

    Directory of Open Access Journals (Sweden)

    Radosław Zajdel

    2013-02-01

    Full Text Available Introduction: Legislation systems of most countries prohibited using the handheld mobile phone while driving due to the fact that it disturbs concentration and causes hand involvement. Every phone owner is accustomed to the ringtone of his phone and almost involuntarily endeavors to pick it up or check who calls. This engages one’s psychomotor skills, which in our opinion contributes to the attenuation of reaction time needed for performing other crucial functions. Objectives: The aim of the study was: (1 to evaluate the infl uence of the sound of a ringing mobile phone on the complex reaction time (RT score in healthy subjects (owners, and (2 to check if there are any differences in RT when a landline phone and mobile phone ring. Methods: To assess RT we used our system and protocol of examination, previously validated. The examination conditions were standardized. All tests were performed in the same room with the same light and general acoustic conditions. The test group consisted of 23 women and 24 men, aged 19–24 years. The examination comprised 4 sessions: Training Session (TS during which the subjects were accustomed with the application and sample stimuli, Control Session (CS with no telephone ringing, Landline Session (LS with landline phone ringing, Mobile Session (MS with mobile phone ringing. Results: The median RT in the study population was signifi cantly elongated (p 0.05. Conclusions: We think that the specifi c ‘bond’ between a person and their private phone can signifi cantly disrupt their attention and thus affect the attention-demanding activities.

  6. Towards autonomous lab-on-a-chip devices for cell phone biosensing.

    Science.gov (United States)

    Comina, Germán; Suska, Anke; Filippini, Daniel

    2016-03-15

    Modern cell phones are a ubiquitous resource with a residual capacity to accommodate chemical sensing and biosensing capabilities. From the different approaches explored to capitalize on such resource, the use of autonomous disposable lab-on-a-chip (LOC) devices-conceived as only accessories to complement cell phones-underscores the possibility to entirely retain cell phones' ubiquity for distributed biosensing. The technology and principles exploited for autonomous LOC devices are here selected and reviewed focusing on their potential to serve cell phone readout configurations. Together with this requirement, the central aspects of cell phones' resources that determine their potential for analytical detection are examined. The conversion of these LOC concepts into universal architectures that are readable on unaccessorized phones is discussed within this context.

  7. Determination of the Antibiotic Resistance Profile of Student Cell Phones

    Directory of Open Access Journals (Sweden)

    Lisa Ann Blankinship

    2012-08-01

    Full Text Available Sampling of common use items (e.g., student cell phones for bacterial presence, identification, and antibiotic resistance profiling helps students to recognize the need for routine cleaning of personal items and encourages thoughtful use of currently available medications. This multilab period project can be used to teach or reinforce several methods from general microbiology including aseptic technique, isolation streak, serial dilution, spread plating, Kirby Bauer testing, unknown identification, and media production. The data generated can be saved and added to each semester, thus providing a data set that reflects a local trend of antibiotic resistance.      

  8. Cell phones and male infertility: a review of recent innovations in technology and consequences

    Directory of Open Access Journals (Sweden)

    Ashok Agarwal

    2011-08-01

    Full Text Available Cell phones have become a vital part of everyday life. However, the health risks associated with their usage are often overlooked. Recently, evidence from several studies supports a growing claim that cell phone usage may have a detrimental effect on sperm parameters leading to decreased male fertility. Nonetheless, other studies showed no conclusive link between male infertility and cell phone usage. The ambiguity of such results is attributed to the lack of a centralized assay for measuring inflicted damage caused by cell phones. Study design, ethics, and reproducibility are all aspects which must be standardized before any conclusions can be made.

  9. Satellite cells in human skeletal muscle plasticity.

    Science.gov (United States)

    Snijders, Tim; Nederveen, Joshua P; McKay, Bryon R; Joanisse, Sophie; Verdijk, Lex B; van Loon, Luc J C; Parise, Gianni

    2015-01-01

    Skeletal muscle satellite cells are considered to play a crucial role in muscle fiber maintenance, repair and remodeling. Our knowledge of the role of satellite cells in muscle fiber adaptation has traditionally relied on in vitro cell and in vivo animal models. Over the past decade, a genuine effort has been made to translate these results to humans under physiological conditions. Findings from in vivo human studies suggest that satellite cells play a key role in skeletal muscle fiber repair/remodeling in response to exercise. Mounting evidence indicates that aging has a profound impact on the regulation of satellite cells in human skeletal muscle. Yet, the precise role of satellite cells in the development of muscle fiber atrophy with age remains unresolved. This review seeks to integrate recent results from in vivo human studies on satellite cell function in muscle fiber repair/remodeling in the wider context of satellite cell biology whose literature is largely based on animal and cell models.

  10. A preliminary investigation into the prevalence and prediction of problematic cell phone use.

    Science.gov (United States)

    Smetaniuk, Peter

    2014-03-01

    Likening mobile phone use dependency to the classification of excessive behaviors may be necessarily equivalent in seriousness to previously established addictions such as problematic computing or excessive gambling. The aim of the study explores into the behavior of excessive use of mobile phones as a pathological behavior. Two studies investigated criteria for problematic mobile phone usage by examining student (Study 1, N = 301) and nonstudent (Study 2, N = 362) responses to a set of adapted mobile phone addiction inventories. Study 1 investigated cell phone addiction inventories as constructs designed to measure problematic cell phone use. Additionally, Study 2 sought to predict age, depression, extraversion, emotional stability, impulse control, and self-esteem as independent variables that augment respondents' perceptions of problematic use. The results from Study 1 and Study 2 indicate that 10 to 25% of the participants tested exhibited problematic cell phone usage. Additionally, age, depression, extraversion, and low impulse control are the most suitable predictors for problematic use. The results of the two studies indicate that problematic mobile phone use does occur and ought to be taken seriously by the psychological community. Presently, there is limited data providing conclusive evidence for a comprehensible categorization of cell phone addiction, as well as a unified explanatory model specific to problematic mobile phone use. Studies such as this one may contribute substantial findings, adding scientific significance, and offering a valuable submission for the ongoing progress of creating intervention frameworks relative to "virtual addictions".

  11. 5373 Volume 11 No. 6 October 2011 TRUST, CELL PHONES ...

    African Journals Online (AJOL)

    Khanjan Mehta

    2011-10-06

    Oct 6, 2011 ... mobile phone enables and accelerates these social network ..... mobile phones, text messaging, and employing the internet for marketing their .... Fafchamps M The enforcement of commercial contracts in Ghana, 3, World.

  12. The Educative Potential of Cell Phones in the Social Studies Classroom

    Science.gov (United States)

    Maguth, Brad M.

    2013-01-01

    Over 75 percent of teens have a cell phone, and today's youth are increasingly turning to their cell phones to communicate and access information (Pew Internet 2009). As teens gain access and use mobile devices outside of the classroom, there's been a growing movement for teachers to enlist the digital tools students really use and are…

  13. The Educative Potential of Cell Phones in the Social Studies Classroom

    Science.gov (United States)

    Maguth, Brad M.

    2013-01-01

    Over 75 percent of teens have a cell phone, and today's youth are increasingly turning to their cell phones to communicate and access information (Pew Internet 2009). As teens gain access and use mobile devices outside of the classroom, there's been a growing movement for teachers to enlist the digital tools students really use and are…

  14. Tools for School: Student Fluency and Perception of Cell Phones Used for Learning

    Science.gov (United States)

    Humble-Thaden, Mary Beth

    2012-01-01

    Technology is changing the way society interacts, communicates, collaborates, and learns. Improved cell phone capabilities and an ever increasing amount of cell phone applications allow individuals to connect globally and afford almost instantaneous access to information inside and outside the classroom. The majority of students today possesses…

  15. Cell Phones in the Classroom: Don't Put Them Away Just Yet!

    Science.gov (United States)

    Webb, Carolyn Lorraine

    2013-01-01

    As the number of students with cell phones has steadily increased over the past decade, these technological advances have caused trepidation among educators over behavioral issues, from off-task activities to cheating (Prensky, 2005). On the other hand, mobile learning, as well as some tools to use with cell phones, are easy to set up, easy to…

  16. Cell Phones in the Classroom: Don't Put Them Away Just Yet!

    Science.gov (United States)

    Webb, Carolyn Lorraine

    2013-01-01

    As the number of students with cell phones has steadily increased over the past decade, these technological advances have caused trepidation among educators over behavioral issues, from off-task activities to cheating (Prensky, 2005). On the other hand, mobile learning, as well as some tools to use with cell phones, are easy to set up, easy to…

  17. Teachers' Stances on Cell Phones in the ESL Classroom: Toward a "Theoretical" Framework

    Science.gov (United States)

    Brown, Jeff

    2014-01-01

    In the ongoing and constantly expanding discussion surrounding cell phones in the classroom, a theoretical complement to the practical side of the issue is generally lacking. This is perhaps understandable. Many teachers are still trying to deal with the simple presence of cell phones in the class, and managing a classroom in which the presence…

  18. Radiofrequency electromagnetic radiation from cell phone causes defective testicular function in male Wistar rats.

    Science.gov (United States)

    Oyewopo, A O; Olaniyi, S K; Oyewopo, C I; Jimoh, A T

    2017-03-06

    Cell phones have become an integral part of everyday life. As cell phone usage has become more widespread, concerns have increased regarding the harmful effects of radiofrequency electromagnetic radiation from these devices. The current study was undertaken to investigate the effects of the emitted radiation by cell phones on testicular histomorphometry and biochemical analyses. Adult male Wistar rats weighing 180-200 g were randomly allotted to control, group A (switched off mode exposure), group B (1-hr exposure), group C (2-hr exposure) and group D (3-hr exposure). The animals were exposed to radiofrequency electromagnetic radiation of cell phone for a period of 28 days. Histomorphometry, biochemical and histological investigations were carried out. The histomorphometric parameters showed no significant change (p radiation of cell phone leads to defective testicular function that is associated with increased oxidative stress and decreased gonadotropic hormonal profile. © 2017 Blackwell Verlag GmbH.

  19. Cell-phone based assistance for waterworks/sewage plant maintenance.

    Science.gov (United States)

    Kawada, T; Nakamichi, K; Hisano, N; Kitamura, M; Miyahara, K

    2006-01-01

    Cell-phones are now incorporating the functions necessary for them to be used as mobile IT devices. In this paper, we present our results of the evaluation of cell-phones as the mobile IT device to assist workers in industrial plants. We use waterworks and sewage plants as examples. By employing techniques to squeeze the SCADA screen on CRT into a small cell-phone LCD, we have made it easier for a plant's field workers to access the information needed for effective maintenance, regardless of location. An idea to link SCADA information and the plant facility information on the cell-phone is also presented. Should an accident or emergency situation arise, these cell-phone-based IT systems can efficiently deliver the latest plant information, thus the worker out in the field can respond to and resolve the emergency.

  20. Appropriation and educational uses of cell phones by students and university teachers

    Directory of Open Access Journals (Sweden)

    Javier Organista Sandoval

    2013-12-01

    Full Text Available Abstract This article presents a study on appropriation and educational uses of cell phones. For the research, a random sample of 954 students and 246 teachers was selected, representing respectively 12% and 24% of the total population in two facilities of UABC in Ensenada, Mexico. Our survey showed that 97% of teachers or students have some kind of cell phone or smartphone. However, we observed that one of every four interactions with the mobile device had a concrete educational purpose. We also found that in general the educational use of the cell phone is mainly aimed to establish communication between the students and to access information via Internet. However, in spite of its limitations, our results show that the cell phone is a technological tool with great pedagogical potential. We suggest that institutional policies are necessary in order to tap that the cell phone potential to adequately support the teaching-learning process.

  1. The Correlation between Cell Phone Use and Sleep Quality in Medical Students

    Directory of Open Access Journals (Sweden)

    Mohamad Reza Bayatiani

    2016-03-01

    Full Text Available Introduction The negative health effects of electromagnetic radiation and psychological dependence are among the major consequences of widespread cell phone use in the general population, especially among adolescents. In this study, the relationship between cell phone use and sleep quality parameters was evaluated. Materials and Methods The study sample consisted of 820 students (305 males and 515 females, recruited from Arak University of Medical Sciences, Arak, Iran. The participants completed Pittsburgh Sleep Quality Index (PSQI and Cell-phone Overuse Scale (COS; the validity of these questionnaires had been previously confirmed in the Iranian population. Information on demographic characteristics and variables associated with cell phone exposure, such as the frequency and duration of phone calls and number of messages was collected in a separate questionnaire. Results Data analysis showed that cell phone overuse was significantly correlated with sleep quality and its components. Moreover, the results indicated that the global PSQI score and some sleep components were significantly correlated with several variables related to cell phone use. Based on the findings, the mean PSQI score was significantly different among heavy and light cell phone users (P

  2. Recovery of indium from LCD screens of discarded cell phones.

    Science.gov (United States)

    Silveira, A V M; Fuchs, M S; Pinheiro, D K; Tanabe, E H; Bertuol, D A

    2015-11-01

    Advances in technological development have resulted in high consumption of electrical and electronic equipment (EEE), amongst which are cell phones, which have LCD (liquid crystal display) screens as one of their main components. These multilayer screens are composed of different materials, some with high added value, as in the case of the indium present in the form of indium tin oxide (ITO, or tin-doped indium oxide). Indium is a precious metal with relatively limited natural reserves (Dodbida et al., 2012), so it can be profitable to recover it from discarded LCD screens. The objective of this study was to develop a complete process for recovering indium from LCD screens. Firstly, the screens were manually removed from cell phones. In the next step, a pretreatment was developed for removal of the polarizing film from the glass of the LCD panels, because the adherence of this film to the glass complicated the comminution process. The choice of mill was based on tests using different equipment (knife mill, hammer mill, and ball mill) to disintegrate the LCD screens, either before or after removal of the polarizing film. In the leaching process, it was possible to extract 96.4 wt.% of the indium under the following conditions: 1.0M H2SO4, 1:50 solid/liquid ratio, 90°C, 1h, and stirring at 500 rpm. The results showed that the best experimental conditions enabled extraction of 613 mg of indium/kg of LCD powder. Finally, precipitation of the indium with NH4OH was tested at different pH values, and 99.8 wt.% precipitation was achieved at pH 7.4.

  3. Cell-phone use diminishes self-awareness of impaired driving.

    Science.gov (United States)

    Sanbonmatsu, David M; Strayer, David L; Biondi, Francesco; Behrends, Arwen A; Moore, Shannon M

    2016-04-01

    Multitasking diminishes the self-awareness of performance that is often essential for self-regulation and self-knowledge. Participants drove in a simulator while either talking or not talking on a hands-free cell phone. Following previous research, participants who talked on a cell phone made more serious driving errors than control participants who did not use a phone while driving. Control participants' assessments of the safeness of their driving and general ability to drive safely while distracted were negatively correlated with the actual number of errors made when they were driving. By contrast, cell-phone participants' assessments of the safeness of their driving and confidence in their driving abilities were uncorrelated with their actual errors. Thus, talking on a cell phone not only diminished the safeness of participants' driving, it diminished their awareness of the safeness of their driving.

  4. The potential role of cell phones in dissemination of bacteria in a healthcare sett

    Directory of Open Access Journals (Sweden)

    Mateusz P. Kister

    2016-04-01

    Full Text Available The mobile phone is an indispensible accessory, both from a social and a professional point of view, which is being used in a variety of environments, including those with high bacteria levels. Medical personnel, patients or even people simply passing by the healthcare facilities, having and using their mobile phones are likely to transmit bacteria, thus it might be suspected that mobile phones are to some extent a link in the cross-contamination. The purpose of this work was to collect information concerning the potential role of cell phones in a dissemination of bacteria based on available research data.

  5. Satellite Cell Heterogeneity in Skeletal Muscle Homeostasis.

    Science.gov (United States)

    Tierney, Matthew T; Sacco, Alessandra

    2016-06-01

    The cellular turnover required for skeletal muscle maintenance and repair is mediated by resident stem cells, also termed satellite cells. Satellite cells normally reside in a quiescent state, intermittently entering the cell cycle to fuse with neighboring myofibers and replenish the stem cell pool. However, the mechanisms by which satellite cells maintain the precise balance between self-renewal and differentiation necessary for long-term homeostasis remain unclear. Recent work has supported a previously unappreciated heterogeneity in the satellite cell compartment that may underlie the observed variability in cell fate and function. In this review, we examine the work supporting this notion as well as the potential governing principles, developmental origins, and principal determinants of satellite cell heterogeneity.

  6. National School Debate: Banning Cell Phones in Public Schools: Analyzing a National School and Community Relations Problem

    Science.gov (United States)

    Johnson, Clarence; Kritsonis, William Allan

    2007-01-01

    School systems in America face many critical challenges pertaining to regulating cell phone use by students in today's schools. School executives and classroom teachers face challenges daily relative to how to effectively deal with student's using cell phones. There are many drawbacks and benefits for cell phone use by students. The authors…

  7. Preliminary research developing a theory of cell phone distraction and social relationships.

    Science.gov (United States)

    LaVoie, Noelle; Lee, Yi-Ching; Parker, James

    2016-01-01

    Motor vehicle crashes remain the leading cause of death and injury for people aged 5-34, accounting annually for over 3000 deaths, and 100 times as many injuries. It is well established that distracted driving, and cell phone use while driving in particular, pose significant crash risk to drivers. Research has demonstrated that drivers are well aware of this danger but over 90% of drivers report using a cell phone while driving. Given the likely role that social influence plays in how people use cell phones while driving surprisingly little research has been conducted investigating to whom drivers are talking or texting. We report the results of a national survey to determine who drivers are most likely to call or text when behind the wheel and compared these results with general cell phone calling and texting patterns as well as previous findings on the prevalence of calling and texting while driving. The results suggest that social distance is a key factor in cell phone use while driving: Teens are more likely to talk with parents, and adults are more likely to talk with spouses than general calling patterns would suggest. We discuss whether the purpose of calls made while driving, such as coordination, could help explain these patterns. We propose next steps for further examining the role social relationships play in cell phone use while driving to potentially reduce teen driver cell phone use by lowering the number of calls from parents.

  8. 75 FR 8921 - Grant of Authority for Subzone Status; Brightpoint North America L.P. (Cell Phone Kitting and...

    Science.gov (United States)

    2010-02-26

    ... Phone Kitting and Distribution) Indianapolis, IN Pursuant to its authority under the Foreign-Trade Zones... authority to establish a special-purpose subzone at the cell phone kitting and distribution facilities of... kitting and distribution of cell phones at the facilities of Brightpoint North America L.P., located...

  9. PRMT7 Preserves Satellite Cell Regenerative Capacity.

    Science.gov (United States)

    Blanc, Roméo Sébastien; Vogel, Gillian; Chen, Taiping; Crist, Colin; Richard, Stéphane

    2016-02-16

    Regeneration of skeletal muscle requires the continued presence of quiescent muscle stem cells (satellite cells), which become activated in response to injury. Here, we report that whole-body protein arginine methyltransferase PRMT7(-/-) adult mice and mice conditionally lacking PRMT7 in satellite cells using Pax7-CreERT2 both display a significant reduction in satellite cell function, leading to defects in regenerative capacity upon muscle injury. We show that PRMT7 is preferentially expressed in activated satellite cells and, interestingly, PRMT7-deficient satellite cells undergo cell-cycle arrest and premature cellular senescence. These defects underlie poor satellite cell stem cell capacity to regenerate muscle and self-renew after injury. PRMT7-deficient satellite cells express elevated levels of the CDK inhibitor p21CIP1 and low levels of its repressor, DNMT3b. Restoration of DNMT3b in PRMT7-deficient cells rescues PRMT7-mediated senescence. Our findings define PRMT7 as a regulator of the DNMT3b/p21 axis required to maintain muscle stem cell regenerative capacity.

  10. PRMT7 Preserves Satellite Cell Regenerative Capacity

    Directory of Open Access Journals (Sweden)

    Roméo Sébastien Blanc

    2016-02-01

    Full Text Available Regeneration of skeletal muscle requires the continued presence of quiescent muscle stem cells (satellite cells, which become activated in response to injury. Here, we report that whole-body protein arginine methyltransferase PRMT7−/− adult mice and mice conditionally lacking PRMT7 in satellite cells using Pax7-CreERT2 both display a significant reduction in satellite cell function, leading to defects in regenerative capacity upon muscle injury. We show that PRMT7 is preferentially expressed in activated satellite cells and, interestingly, PRMT7-deficient satellite cells undergo cell-cycle arrest and premature cellular senescence. These defects underlie poor satellite cell stem cell capacity to regenerate muscle and self-renew after injury. PRMT7-deficient satellite cells express elevated levels of the CDK inhibitor p21CIP1 and low levels of its repressor, DNMT3b. Restoration of DNMT3b in PRMT7-deficient cells rescues PRMT7-mediated senescence. Our findings define PRMT7 as a regulator of the DNMT3b/p21 axis required to maintain muscle stem cell regenerative capacity.

  11. Regulation of satellite cell function in sarcopenia

    Directory of Open Access Journals (Sweden)

    Stephen E Alway

    2014-09-01

    Full Text Available The mechanisms contributing to sarcopenia include reduced satellite cell (myogenic stem cell function that is impacted by the environment (niche of these cells. Satellite cell function is affected by oxidative stress, which is elevated in aged muscles, and this along with changes in largely unknown systemic factors, likely contribute to the manner in which satellite cells respond to stressors such as exercise, disuse or rehabilitation in sarcopenic muscles. Nutritional intervention provides one therapeutic strategy to improve the satellite cell niche and systemic factors, with the goal of improving satellite cell function in aging muscles. Although many elderly persons consume various nutraceuticals with the hope of improving health, most of these compounds have not been thoroughly tested, and the impacts that they might have on sarcopenia, and satellite cell function are not clear. This review discusses data pertaining to the satellite cell responses and function in aging skeletal muscle, and the impact that three compounds: resveratrol, green tea catechins and β-Hydroxy-β-methylbutyrate have on regulating satellite cell function and therefore contributing to reducing sarcopenia or improving muscle mass after disuse in aging. The data suggest that these nutraceutical compounds improve satellite cell function during rehabilitative loading in animal models of aging after disuse (i.e., muscle regeneration. While these compounds have not been rigorously tested in humans, the data from animal models of aging provide a strong basis for conducting additional focused work to determine if these or other nutraceuticals can offset the muscle losses, or improve regeneration in sarcopenic muscles of older humans via improving satellite cell function.

  12. Is mobile phone radiation genotoxic? An analysis of micronucleus frequency in exfoliated buccal cells.

    Science.gov (United States)

    de Oliveira, F M; Carmona, A M; Ladeira, C

    2017-10-01

    Electromagnetic fields (EMF) are classified as "possibly carcinogenic" by the International Agency for Research on Cancer (IARC). Some publications have reported associations between EMF exposure and DNA damage, but many other studies contradict such findings. Cytomorphological changes, such as micronuclei (MN), indicative of genomic damage, are biomarkers of genotoxicity. To test whether mobile phone-associated EMF exposure affects the MN frequency in exfoliated buccal cells, we obtained cells smears from the left and right inner cheeks of healthy mobile phone users, aged 18-30 (n=86), who also completed a characterization survey. MN frequencies were tested for potential confounding factors and for duration of phone use and preferential side of mobile phone use. No relationship was observed between MN frequency and duration of mobile phone use in daily calls. Cells ipsilateral to mobile phone use did not present a statistically significantly higher MN frequency, compared to cells contralateral to exposure. A highly statistically significant (pmobile phone-associated EMF do not to induce MN formation in buccal cells at the observed exposure levels. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. A feasibility study of cell phone and landline phone interviews for monitoring of risk and protection factors for chronic diseases in Brazil

    Directory of Open Access Journals (Sweden)

    Erly Catarina Moura

    2011-02-01

    Full Text Available The study objective was to evaluate the feasibility of interviews by cell phone as a complement to interviews by landline to estimate risk and protection factors for chronic non-communicable diseases. Adult cell phone users were evaluated by random digit dialing. Questions asked were: age, sex, education, race, marital status, ownership of landline and cell phones, health condition, weight and height, medical diagnosis of hypertension and diabetes, physical activity, diet, binge drinking and smoking. The estimates were calculated using post-stratification weights. The cell phone interview system showed a reduced capacity to reach elderly and low educated populations. The estimates of the risk and protection factors for chronic non-communicable diseases in cell phone interviews were equal to the estimates obtained by landline phone. Eligibility, success and refusal rates using the cell phone system were lower than those of the landline system, but loss and cost were much higher, suggesting it is unsatisfactory as a complementary method in such a context.

  14. Cell Phone-based Lateral Flow Assay for Blood Biomarker Detection Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The ability to integrate a sensor platform with a cell phone for health monitoring and disease diagnosis for astronauts in space exploration has the potential to be...

  15. Cell Phone-based Lateral Flow Assay for Blood Biomarker Detection Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The ability to integrate a sensor platform with a cell phone for health monitoring and disease diagnosis for astronauts in space has the potential to be cost...

  16. Cellular Phone Towers, Cell Towers, Published in unknown, Norton County Appraisal Office.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, was produced all or in part from Other information as of unknown. It is described as 'Cell Towers'. Data by this publisher are...

  17. Effect of Cell Phone Radiations on Orofacial Structures: A Systematic Review

    Science.gov (United States)

    Chowdhary, Ramesh; Kumari, Shail; Rao, Srinivasa B

    2017-01-01

    Introduction: The widespread use of cell phone in recent years has raised many questions whether their use is safe to operator who is exposed to Electromagnetic Waves (EMV). Aim To find out the effect of cell phone emitted radiations on the orofacial structures. Materials and Methods To identify suitable literature, an electronic search was performed using Medline, Pubmed and EBSCO host database in December 2016. The search was focused on effect of cell phone on orofacial structures. Among the literature available in English, the screening of the related titles and abstracts was done, and only those articles were selected for full text reading that fulfilled the inclusion criteria. Results The initial literature search resulted in 360 articles out of which only 24 articles fulfilled the inclusion criteria and were included in this systematic review. Conclusion Cell phone emitted radiations had their adverse effect on salivary glands and facial nerves. Studies showed that cell phone emitted radiations had effects on oral mucosal cells and causes changes in salivary flow rate. It was still unclear that cell phone radiations cause tumours of the salivary glands. PMID:28658925

  18. Effect of Cell Phone Radiations on Orofacial Structures: A Systematic Review.

    Science.gov (United States)

    Mishra, Sunil Kumar; Chowdhary, Ramesh; Kumari, Shail; Rao, Srinivasa B

    2017-05-01

    The widespread use of cell phone in recent years has raised many questions whether their use is safe to operator who is exposed to Electromagnetic Waves (EMV). To find out the effect of cell phone emitted radiations on the orofacial structures. To identify suitable literature, an electronic search was performed using Medline, Pubmed and EBSCO host database in December 2016. The search was focused on effect of cell phone on orofacial structures. Among the literature available in English, the screening of the related titles and abstracts was done, and only those articles were selected for full text reading that fulfilled the inclusion criteria. The initial literature search resulted in 360 articles out of which only 24 articles fulfilled the inclusion criteria and were included in this systematic review. Cell phone emitted radiations had their adverse effect on salivary glands and facial nerves. Studies showed that cell phone emitted radiations had effects on oral mucosal cells and causes changes in salivary flow rate. It was still unclear that cell phone radiations cause tumours of the salivary glands.

  19. Contamination of cell phones by pathogenic microorganisms: Comparison between hospital staff and college students

    Directory of Open Access Journals (Sweden)

    PURNIMA R. CHITLANGE

    2014-11-01

    Full Text Available Chitlange PR. 2014. Contamination of cell phones by pathogenic microorganisms: Comparison between hospital staff and college students. Nusantara Bioscience 6: 203-206. Cell phone (CP is a long range portable electronic device. The cell phone is constantly exposed to arrays of micro organisms, making it a harbour and breeding ground for microbes especially those associated with skin. The adult human is covered with approximately 2m2 of skin with area supporting about 106 bacteria. To check whether the cell phone act as a vector for transmission of various pathogens, a potential study was carried out in microbiology department of Shri Radhakisan Laxminarayan Toshniwal College of Science, Akola. Total 20 cell samples were screened. Two parameters were considered: College students and hospital staff. The isolated bacteria Staphylococcus aureus, E. coli, Pseudomonas sp., Bacillus subtilis, Aerobacter aerogenes, Salmonella, Shigella, Streptococci, P. vulgaris were identified on the basis of morphological and cultural characteristics. The main aim of present study was to check the contamination by bacterial pathogens on cell phones and also to check role of cell phone for transmission of pathogens from person to person or not.

  20. Problematic Internet and Cell-Phone Use: Psychological, Behavioral, and Health Correlates

    OpenAIRE

    Jenaro Río, Cristina; Flores Robaina, Noelia; Gómez Vela, María; González Gil, Francisca; Caballo Escribano, Cristina

    2007-01-01

    [EN]This study aimed to assess pathological Internet and cell-phone use in college students, and to identify psychological, health, and behavioral correlates. A cross-sectional design was utilized to gather data from 337 students. We developed two measures, termed the Internet Over-use Scale (IOS), and the Cell-Phone Over-Use Scale (COS). Additional measures utilized were the Beck Anxiety Inventory, the Beck Depression Inventory, and the General Health Questionnaire-28. Results provide suppor...

  1. Providing cell phone numbers and email addresses to Patients: the physician's perspective

    Directory of Open Access Journals (Sweden)

    Freud Tamar

    2011-03-01

    Full Text Available Abstract Background The provision of cell phone numbers and email addresses enhances the accessibility of medical consultations, but can add to the burden of physicians' routine clinical practice and affect their free time. The objective was to assess the attitudes of physicians to providing their telephone number or email address to patients. Methods Primary care physicians in the southern region of Israel completed a structured questionnaire that related to the study objective. Results The study population included 120 primary care physicians with a mean age of 41.2 ± 8.5, 88 of them women (73.3%. Physicians preferred to provide their cell phone number rather than their email address (P = 0.0007. They preferred to answer their cell phones only during the daytime and at predetermined times, but would answer email most hours of the day, including weekends and holidays (P = 0.001. More physicians (79.7% would have preferred allotted time for email communication than allotted time for cell phone communication (50%. However, they felt that email communication was more likely to lead to miscommunication than telephone calls (P = 0.0001. There were no differences between male and female physicians on the provision of cell phone numbers or email addresses to patients. Older physicians were more prepared to provide cell phone numbers that younger ones (P = 0.039. Conclusions The attitude of participating physicians was to provide their cell phone number or email address to some of their patients, but most of them preferred to give out their cell phone number.

  2. Media Discourse on Cell Phone Technology and “Left-Behind Children” in China

    Directory of Open Access Journals (Sweden)

    Janice Hua Xu

    2016-06-01

    Full Text Available Through critical analysis of selected news stories from sina.com from 2010 to 2015 about cell phones and “left-behind children” in China, this article examines media discourses on the relationship between migrant families and communication technology. The author finds that the roles of cell phones in their lives are portrayed in the following narratives: 1 cell phones are highly valuable for connecting family members living apart; 2 cell phones are used as a problem-solver in charity giving and rural development projects; 3 cell phones can bring unexpected risks to children lacking media literacy; and 4 cell phones could harbour or unleash evil—associated with increasing cases of juvenile delinquency or crime stories. The author discusses how the different institutional goals of social agencies, corporations, educators, and law enforcement contribute to the polarity of the discourses, reflecting the societal anxieties over unsupervised use of mobile devices by adolescents, as well as the cultural and political implications of empowering the “have-nots” of the digital divide by improving access to communication technology.

  3. In the shadow of the cell-phone

    DEFF Research Database (Denmark)

    Hansen, Lone Koefoed

    2009-01-01

    Based on discussions of hybrid space as well as the concepts of the database and archive art, the paper analyzes Hasan Elahi’s project “Tracking Transience” (2003-) and relates it to Sophie Calle’s performance “Detective” (1980) while discussing how we can understand the mobile phone as a device ...... to an enormous amount of data, we are left with a feeling of following a shadow or maybe a mirage. This paper explores how the mobile phone affords this playing hide-and-seek, and the way that it provides shelter from the inspecting eye...

  4. "The Only 13-Year-Old on Planet Earth without a Cell Phone": Meanings of Cell Phones in Early Adolescents' Everyday Lives

    Science.gov (United States)

    Blair, Bethany L.; Fletcher, Anne C.

    2011-01-01

    Cellular telephones have become an increasingly prevalent feature of contemporary American life, with usage often beginning during early adolescence. With this in mind, twenty 7th graders and their mothers participated in separate qualitative interviews regarding early adolescents' use of cell phones as well as perceived risks and benefits of such…

  5. Cell Phones to Collect Pregnancy Data From Remote Areas in Liberia

    Science.gov (United States)

    Lori, Jody R.; Munro, Michelle L.; Boyd, Carol J.; Andreatta, Pamela

    2012-01-01

    Purpose To report findings on knowledge and skill acquisition following a 3-day training session in the use of short message service (SMS) texting with non- and low-literacy traditional midwives. Design A pre- and post-test study design was used to assess knowledge and skills acquisition with 99 traditional midwives on the use of SMS texting for real-time, remote data collection in rural Liberia, West Africa. Methods Paired sample t-tests were conducted to establish if overall mean scores varied significantly from pre-test to immediate post-test. Analysis of variance was used to compare means across groups. The nonparametric McNemar’s test was used to determine significant differences between the pre-test and post-test values of each individual step involved in SMS texting. Pearson’s chi-square test of independence was used to examine the association between ownership of cell phones within a family and achievement of the seven tasks. Findings The mean increase in cell phone knowledge scores was 3.67, with a 95% confidence interval ranging from 3.39 to 3.95. Participants with a cell phone in the family did significantly better on three of the seven tasks in the pre-test: “turns cell on without help” (χ2(1) = 9.15, p = .003); “identifies cell phone coverage” (χ2(1) = 5.37, p = .024); and “identifies cell phone is charged” (χ2(1) = 4.40, p = .042). Conclusions A 3-day cell phone training session with low- and nonliterate traditional midwives in rural Liberia improved their ability to use mobile technology for SMS texting. Clinical Relevance Mobile technology can improve data collection accessibility and be used for numerous healthcare and public health issues. Cell phone accessibility holds great promise for collecting health data in low-resource areas of the world. PMID:22672157

  6. Who needs RDD? Combining directory listings with cell phone exchanges for an alternative telephone sampling frame

    OpenAIRE

    Guterbock, Thomas; Diop, Abdoulaye; Ellis, James; Trung Le, Kien

    2011-01-01

    Abstract The traditional Random Digit Dialing method (list-assisted RDD using a frame of landline phone numbers) is clearly under threat. The difficulty and costs of completing telephone surveys have increased due to rising rates of refusal and non-contact. The completeness of coverage of list-assisted RDD samples has diminished due to the proliferation of cell-phone only households. The ability of list-assisted RDD to capture young, mobile, unmarried, and minority households is thus dimin...

  7. In the shadow of the cell-phone

    DEFF Research Database (Denmark)

    Hansen, Lone Koefoed

    2009-01-01

    mobile phone, which meticulously tracks his life. However, even though Elahi’s life seems to be thoroughly and intimately documented with pictures of e.g. every eaten meal and every visited restroom, we are clearly not getting the full picture. Consequently, despite having been granted access...

  8. Integrating Cell Phones into the Secondary Montessori Classroom

    Science.gov (United States)

    DeWitte, Cynthia M.

    2010-01-01

    A disconnect exists between how students communicate using their mobile phones outside of school and how they use them in the classroom. Many high schools across the United States ban their use, even though numerous mobile learning strategies are available. Although research pertaining to m-learning has been conducted at the collegiate level, a…

  9. Gas detection with microelectromechanical Fabry-Perot interferometer technology in cell phone

    Science.gov (United States)

    Mannila, Rami; Hyypiö, Risto; Korkalainen, Marko; Blomberg, Martti; Kattelus, Hannu; Rissanen, Anna

    2015-06-01

    VTT Technical Research Centre of Finland has developed a miniaturized optical sensor for gas detection in a cell phone. The sensor is based on a microelectromechanical (MEMS) Fabry-Perot interferometer, which is a structure with two highly reflective surfaces separated by a tunable air gap. The MEMS FPI is a monolithic device, i.e. it is made entirely on one substrate in a batch process, without assembling separate pieces together. The gap is adjusted by moving the upper mirror with electrostatic force, so there are no actual moving parts. VTT has designed and manufactured a MEMS FPI based carbon dioxide sensor demonstrator which is integrated to a cell phone shield cover. The demonstrator contains light source, gas cell, MEMS FPI, detector, control electronics and two coin cell batteries as a power source. It is connected to the cell phone by Bluetooth. By adjusting the wavelength range and customizing the MEMS FPI structure, it is possible to selectively sense multiple gases.

  10. A STUDY ON BACTERIAL CONTAMINATION OF CELL PHONES OF HEALTH CARE WORKERS (HCW AT KIMS HOSPITAL, AMALAPURAM

    Directory of Open Access Journals (Sweden)

    Padmaja

    2014-04-01

    Full Text Available A random 100 samples of cell phones of HCWs workers and Doctors working in various wards, OPDs and laboratories, Blood Bank, Causality, ICU of KIMS Hospital were subjected to bacterial analysis by conventional methods to know about the Bacterial contamination of the cell phones from July 2011 to December 2011. The commonest organism isolated from the contaminated cell phone is MRSA - 20%, followed by MSSA - 5%, CONS - 10 %, Micrococcus - 15 %. The obvious observation is none of the doctors’ cell phones are contaminated. In the present study, the contamination rate is compared to the controlled group consisting patients, relatives attending in OPD’s and not working in health care setting.

  11. Telemedicine through the use of digital cell phone technology in pediatric neurosurgery: a case series.

    Science.gov (United States)

    Pirris, Stephen M; Monaco, Edward A; Tyler-Kabara, Elizabeth C

    2010-05-01

    Advances in medicine have largely followed advances in technology. Medical strides have been made when physicians and researchers have adapted growing science to target specific problems. A new medical field, telemedicine, has emerged that links physicians with colleagues and patients. Cell phone technology is affordable for almost everyone, and basic models include digital photography. We present a case series exhibiting the utility of digital pictures taken with patients' cell phones. Our patients had wound infections requiring daily intravenous antibiotics and dressing changes. In years past, these patients would have required prolonged hospitalizations. In the era of managed care, patients with these infections are discharged from the hospital, but close outpatient observation is required to monitor the wound. Our patients lived up to 8 hours away from the hospital. Daily appointments for wound checks in the clinic were not practical. Wounds were thus monitored via cell phone images without the inconvenience of travel and the expense of staying in a local hotel, along with leaving appointments in the clinic available for others with new neurosurgical issues. Wound evaluations were conducted with the cameras on patients' cell phones. These images were transmitted to the surgeon via text messaging and emails. This application of cell phone technology has been documented previously in the literature of other specialties and could attain greater stature as a legitimate method for close outpatient observation by neurosurgeons if medicolegal issues are addressed.

  12. Determination of Invisible Environmental Pollution Due to Cell Phones EMF Radiation and projections for 2030

    Directory of Open Access Journals (Sweden)

    K Parandham Gowd

    2013-08-01

    Full Text Available In the last decades cell phones usage have altered the land scape of modern human beings in countless ways, in office, at home and on mobility. However, created the environmental electronic pollution due to electromagnetic fields. In spite of the recent studies indicating possible harmful impact of EMF pollution on several species, there is no long term data available on the environmental impacts of EMF pollution and how much power density is radiated in the environment due to cell phones. The aim of this research work is to experimentally measure the EMF radiated electronic pollution levels of cell phones in three different states such as on(sleep/idle mode, receive and transmit modes as an invisible environmental pollution. These measurements are carried out at the centre frequency of 1800 MHz and in the 300 MHz- 50 GHz frequency band. Another main aim is to carry out the projections of cell phones growth due to exponentially expanding mobile technology products, industrialization along with urbanization. Further to estimate the current (2013 EMF radiation pollution levels into environment and projections for 2030 due to cell phones.

  13. Cancer risks related to low-level RF/MW exposures, including cell phones.

    Science.gov (United States)

    Szmigielski, Stanislaw

    2013-09-01

    For years, radiofrequency (RF) and microwave (MW) radiations have been applied in the modern world. The rapidly increasing use of cellular phones called recent attention to the possible health risks of RF/MW exposures. In 2011, a group of international experts organized by IARC (International Agency for Research on Cancer in Lyon) concluded that RF/MW radiations should be listed as a possible carcinogen (group 2B) for humans. Three meta-analyses of case-control studies have concluded that using cell phones for more than ten years was associated with an increase in the overall risk of developing a brain tumor. The Interphone Study, the largest health-related case-control international study of use of cell phones and head and neck tumors, showed no statistically significant increases in brain cancers related to higher amounts of cell phone use, but excess risk in a small subgroup of more heavily exposed users associated with latency and laterality was reported. So far, the published studies do not show that mobile phones could for sure increase the risk of cancer. This conclusion is based on the lack of a solid biological mechanism, and the fact that brain cancer rates are not going up significantly. However, all of the studies so far have weaknesses, which make it impossible to entirely rule out a risk. Mobile phones are still a new technology and there is little evidence about effects of long-term use. For this reason, bioelectromagnetic experts advise application of a precautionary resources. It suggests that if people want to use a cell phone, they can choose to minimize their exposure by keeping calls short and preferably using hand-held sets. It also advises discouraging children from making non essential calls as well as also keeping their calls short.

  14. Effects of non-thermal mobile phone radiation on breast adenocarcinoma cells

    Directory of Open Access Journals (Sweden)

    Zen Fourie

    2011-09-01

    Full Text Available Mobile phone usage currently exceeds landline communication in Africa. The extent of this usage has raised concerns about the long-term health effects of the ongoing use of mobile phones. To assess the physiological effects of radiation from mobile phones in vitro, MCF-7 breast adenocarcinoma cells were exposed to 2W/kg non-thermal 900-MHz mobile phone radiation. The effects investigated were those on metabolic activity, cell morphology, cell cycle progression, phosphatidylserine (PS externalisation and the generation of reactive oxygen species and nitrogen species. Statistically insignificant increases in mitochondrial dehydrogenase activity were observed in irradiated cells when compared to controls. Fluorescent detection of F-actin demonstrated an increase in F-actin stress fibre formation in irradiated MCF-7 cells. Cell cycle progression revealed no statistically significant variation. A small increase in early and late apoptotic events in irradiated MCF-7 cells was observed. No statistically significant changes were observed in reactive oxygen and reactive nitrogen species generation. In addition, quantitative and qualitative analyses of cell cycle activity and nuclear and cytosolic changes, respectively, revealed no significant changes. In conclusion, exposure to 1 h of 900-MHz irradiation induced an increase in PS externalisation and an increase in the formation of F-actin stress fibres in MCF-7 cells. Data obtained from this study, and their correlation with other studies, provides intriguing links between radio frequency radiation and cellular events and warrant further investigation.

  15. Detecting particles with cell phones: the Distributed Electronic Cosmic-ray Observatory

    CERN Document Server

    Vandenbroucke, Justin; Karn, Peter; Meehan, Matthew; Plewa, Matthew; Ruggles, Tyler; Schultz, David; Peacock, Jeffrey; Simons, Ariel Levi

    2015-01-01

    In 2014 the number of active cell phones worldwide for the first time surpassed the number of humans. Cell phone camera quality and onboard processing power (both CPU and GPU) continue to improve rapidly. In addition to their primary purpose of detecting photons, camera image sensors on cell phones and other ubiquitous devices such as tablets, laptops and digital cameras can detect ionizing radiation produced by cosmic rays and radioactive decays. While cosmic rays have long been understood and characterized as a nuisance in astronomical cameras, they can also be identified as a signal in idle camera image sensors. We present the Distributed Electronic Cosmic-ray Observatory (DECO), a platform for outreach and education as well as for citizen science. Consisting of an app and associated database and web site, DECO harnesses the power of distributed camera image sensors for cosmic-ray detection.

  16. Adapting to Student Learning Styles: Using Cell Phone Technology in Undergraduate Science Instruction

    Directory of Open Access Journals (Sweden)

    Richard Pennington

    2010-10-01

    Full Text Available Students of science traditionally make 3x5 flash cards to assist learning nomenclature, structures, and reactions. Advances in educational technology have enabled flashcards viewed on computers, offering an endless array of drilling and feedback opportunities for students. The current generation of students is less inclined to use computers, but they use their cell phones 24 hours a day. This report outlines these trends and an even more recent educational technology initiative, that of using cell phone flash cards to help students learn biology and chemistry nomenclature, structures, and reactions. Students responded positively to cell phone flash cards in a pilot study and a more detailed study is planned for the coming year.

  17. Adapting to Student Learning Styles: Using Cell Phone Technology in Undergraduate Science Instruction

    Directory of Open Access Journals (Sweden)

    Richard Pennington

    2010-10-01

    Full Text Available Students of science traditionally make 3x5 flash cards to assist learning nomenclature, structures, and reactions. Advances in educational technology have enabled flashcards viewed on computers, offering an endless array of drilling and feedback opportunities for students. The current generation of students is less inclined to use computers, but they use their cell phones 24 hours a day. This report outlines these trends and an even more recent educational technology initiative, that of using cell phone flash cards to help students learn biology and chemistry nomenclature, structures, and reactions. Students responded positively to cell phone flash cards in a pilot study and a more detailed study is planned for the coming year.

  18. Prevalence of problematic cell phone use in an adult population in Spain as assessed by the Mobile Phone Problem Use Scale (MPPUS).

    Science.gov (United States)

    de-Sola, José; Talledo, Hernán; Rodríguez de Fonseca, Fernando; Rubio, Gabriel

    2017-01-01

    Problematic cell phone use has alarmingly increased in industrialized countries in the past 10 years. For many perpetrators, it can turn into a behavioural addiction, although this is not a recognized medical condition. Although there are many tools for evaluating this use, one of the most widely used tools is the Mobile Phone Problematic Use Scale (MPPUS), which we test on a representative sample of the population in Spain to obtain an estimate of the prevalence of problematic cell phone use in our midst. The age range consists of 16-65 years, with 1,126 surveys conducted. In this population, we verify that the reliability and internal consistency of the MPPUS (α = 0.939) are maintained. Additionally, the construct validity, considering the derived factors (Abuse and Dependence, Craving and Loss of Control, and Dependence on the Social Environment) are aligned with other research and with diverse external criteria of addiction. We establish four categories of users (Casual, Regular, At Risk, and Problematic) and obtain a prevalence of 15.4% among At Risk Users and 5.1% among Problematic Users. This finding implies a total of 20.5% of Users with Problems. A binary logistic regression analysis shows that age, gender, level of education, and daily cell phone use predict problematic cell phone use. The results, based on multiple criteria, show that such problematic use shares features of recognized addictions, affecting large segments of the population and not only adolescents.

  19. Mass SAR Test of Cell Phone%手机批量SAR测试方案

    Institute of Scientific and Technical Information of China (English)

    何毅; 范伟杰

    2013-01-01

    SAR is internationally adopted to measure the radiation, but the SAR test of cell phone is a complicated process. Based on the fundamental knowledge of cell phone SAR and the French SAGEM Laboratory Testing System, this paper presents the fundamental theories and key points of the Laboratory Testing System. The major factors which influence the cell phone SAR are analyzed from the aspects of the different circumstances of laboratory environment and the SAR test results of different cell phone models; the correlation between the factors and the SAR is studied. The cell phone SAR is simulated indirectly and a feasible scheme is obtained for the mass SAR test of cell phones.%国际上通行的方法是用比吸收率(SAR)来衡量手机辐射大小,但是手机SAR的测试又是一个非常复杂的过程。本文在介绍手机SAR的基本知识和法国SAGEM实验室测试系统的基础上,对实验室SAR测试的基本原理和要点做了归纳,通过对实验室环境下对各种情况、各个型号手机SAR的测试结果分析,分析手机SAR的主要影响因素,通过对这些影响因素与SAR关系的研究;来间接模拟手机SAR,以获得可用于批量手机SAR测试的可行性方案。

  20. Embedded Adaptive Optics for Ubiquitous Lab-on-a-Chip Readout on Intact Cell Phones

    Directory of Open Access Journals (Sweden)

    Pakorn Preechaburana

    2012-06-01

    Full Text Available The evaluation of disposable lab-on-a-chip (LOC devices on cell phones is an attractive alternative to migrate the analytical strength of LOC solutions to decentralized sensing applications. Imaging the micrometric detection areas of LOCs in contact with intact phone cameras is central to provide such capability. This work demonstrates a disposable and morphing liquid lens concept that can be integrated in LOC devices and refocuses micrometric features in the range necessary for LOC evaluation using diverse cell phone cameras. During natural evaporation, the lens focus varies adapting to different type of cameras. Standard software in the phone commands a time-lapse acquisition for best focal selection that is sufficient to capture and resolve, under ambient illumination, 50 μm features in regions larger than 500 × 500 μm2. In this way, the present concept introduces a generic solution compatible with the use of diverse and unmodified cell phone cameras to evaluate disposable LOC devices.

  1. Coded illumination for motion-blur free imaging of cells on cell-phone based imaging flow cytometer

    Science.gov (United States)

    Saxena, Manish; Gorthi, Sai Siva

    2014-10-01

    Cell-phone based imaging flow cytometry can be realized by flowing cells through the microfluidic devices, and capturing their images with an optically enhanced camera of the cell-phone. Throughput in flow cytometers is usually enhanced by increasing the flow rate of cells. However, maximum frame rate of camera system limits the achievable flow rate. Beyond this, the images become highly blurred due to motion-smear. We propose to address this issue with coded illumination, which enables recovery of high-fidelity images of cells far beyond their motion-blur limit. This paper presents simulation results of deblurring the synthetically generated cell/bead images under such coded illumination.

  2. [Internet and cell phone addiction: passing fad or disorder?].

    Science.gov (United States)

    Sanchez-Carbonell, Xavier; Beranuy, Marta; Castellana, Montserrat; Chamarro, Ander; Oberst, Ursula

    2008-01-01

    The Information and Communication Technologies (ICT) generate new styles of meeting people or connecting with friends or strangers. In this context, the internet and the mobile phone deserve special attention. This article deals with the maladaptive use of these technologies. By reviewing the literature published between 1991 and 2005 and indexed in the databases of PsycINFO, Medline, Psicodoc, IME, and ISOC, we aim to determine whether maladaptive use of these technologies can be considered a mental disorder, and if so, of which type. We describe the psychological phenomena of maladaptive use of the internet and mobile phones, we review research on prevalence and possible risk groups, and finally we discuss some of the criticisms made with regard to the existence and classification of this disorder. It is concluded that excessive use of the internet can lead to a mental disorder of the addictive type, which can particularly affect individuals with special emotional needs, as well as adolescents and young adults. Among specific applications of the internet, a major risk is found for the use of communicative and synchronic applications, such as chats and online role games, since they permit hyperpersonal communication, playing with different identities, and projections and dissociation without consequences in real life. Furthermore, the internet can play an important role in the development and maintenance of other addictions, such as pathological gambling and sex addiction. In contrast to the case of the internet, maladaptive use of mobile phones may be considered abuse, but not addiction, since their use does not lead to the rapid emotional changes or the playing with identities that can take place in chats and online role games.

  3. The Cost of Privacy: Riley v. California's Impact on Cell Phone Searches

    Directory of Open Access Journals (Sweden)

    Jennifer Moore

    2014-09-01

    Full Text Available Riley v. California is the United States Supreme Court’s first attempt to regulate the searches of cell phones by law enforcement.  The 2014 unanimous decision requires a warrant for all cell phone searches incident to arrest absent an emergency.  This work summarizes the legal precedent and analyzes the limitations and practical implications of the ruling.  General guidelines for members of the criminal justice system at all levels consistent with the Supreme Court’s decision are provided.  

  4. Effect of Green Tea Extract in Reducing Genotoxic Injuries of Cell Phone Microwaves on Bone Marrow

    Directory of Open Access Journals (Sweden)

    Zahra Zahedifar

    2013-11-01

    Full Text Available Background: Green tea (Camellia sinensis extract is rich source of natural antioxidants specially catechin that is quickly absorbed into the body and it has cancer protective, anti microbial and anti inflammation effects. In this study has been studied role of green tea extract against genotoxic damage induced by cell phone microwaves on bone marrow polychromatic erythrocytes of adult male Balb/C mouse.Materials and Methods: In this experimental study 40 mouse were divided into five groups, control animals were located under natural condition, sham -exposed animals were prepared by experimental condition without cell phone waves radiation. Experimental 1 group that irradiated at cell phones for 4 days (3 hours/day and experimental 2 groups were injected intraperitoneal 100 mg/kg green tea extract for 5 days and experimental 3 group that irradiated at active mobile phones for 4 days (3 hours/day and were injected intraperitoneal 100 mg/kg green tea extract for 5 days. After treatment period micronucleus test was evaluated in polychromatic erythrocytes on bone marrow. The quantitative data was analyzed by ANOVA and Tukey test with using of SPSS-13 software at the level of p<0.05.Results: Based on this study, treatment with extracts of green tea decreased micronucleus frequency in bone marrow polychromatic erythrocytes of Balb/C mouse that irradiated at cell phone microwave (0.92±0.129, (p<0.001.Conclusion: Cell phone microwaves (940 MHz increased micronucleus on bone marrow polychromatic erythrocytes of male Balb/C mouse, but green tea had inhibitory effect and it decreased the average number of micronucleus.

  5. Life cycle assessment of cell phones in Brazil based on two reverse logistics scenarios

    Directory of Open Access Journals (Sweden)

    Daniela da Gama e Silva Volpe Moreira de Moraes

    2014-12-01

    Full Text Available This article is a result of a cell phone collection obtained at the Center for Information Technology Renato Archer (CTI under the AMBIENTRONIC Program, an initiative that supports the Brazilian electronic sector in the development of technologies for sustainability. The objective of this article is to assess two reverse logistic scenarios of cell phones using the technique of life-cycle assessment (LCA. The first scenario reflects the current scenario in Brazil, where batteries are recycled in Brazil and the other parts of the phones are outsourced to Europe. The second scenario is a proposal of full treatment in Brazil. The results indicate that the second scenario has a lower potential impact with important reduction of acidification, photochemical oxidation, eutrophication and the use of non-renewable energy. Furthermore, fully implementing reverse logistics in Brazil will enable socioeconomic benefits from the sale of materials and the generation of employment and income.

  6. Language and Social Factors in the Use of Cell Phone Technology by Adolescents with and without Specific Language Impairment (SLI)

    Science.gov (United States)

    Conti-Ramsden, Gina; Durkin, Kevin; Simkin, Zoe

    2010-01-01

    Purpose: This study aimed to compare cell phone use (both oral and text-based) by adolescents with and without specific language impairment (SLI) and examine the extent to which language and social factors affect frequency of use. Method: Both interview and diary methods were used to compare oral and text-based communication using cell phones by…

  7. Muscle Satellite Cell Heterogeneity and Self-Renewal

    Directory of Open Access Journals (Sweden)

    Norio eMotohashi

    2014-01-01

    Full Text Available Adult skeletal muscle possesses extraordinary regeneration capacities. After muscle injury or exercise, large numbers of newly formed muscle fibers are generated within a week as a result of expansion and differentiation of a self-renewing pool of muscle stem cells termed muscle satellite cells. Normally, satellite cells are mitotically quiescent and reside beneath the basal lamina of muscle fibers. Upon regeneration, satellite cells are activated, and give rise to daughter myogenic precursor cells. After several rounds of proliferation, these myogenic precursor cells contribute to the formation of new muscle fibers. During cell division, a minor population of myogenic precursor cells returns to quiescent satellite cells as a self-renewal process. Currently, accumulating evidence has revealed the essential roles of satellite cells in muscle regeneration and the regulatory mechanisms, while it still remains to be elucidated how satellite cell self-renewal is molecularly regulated and how satellite cells are important in aging and diseased muscle. The number of satellite cells is decreased due to the changing niche during ageing, resulting in attenuation of muscle regeneration capacity. Additionally, in Duchenne muscular dystrophy (DMD patients, the loss of satellite cell regenerative capacity and decreased satellite cell number due to continuous needs for satellite cells lead to progressive muscle weakness with chronic degeneration. Thus, it is necessary to replenish muscle satellite cells continuously. This review outlines recent findings regarding satellite cell heterogeneity, asymmetric division and molecular mechanisms in satellite cell self-renewal which is crucial for maintenance of satellite cells as a muscle stem cell pool throughout life. In addition, we discuss roles in the stem cell niche for satellite cell maintenance, as well as related cell therapies for approaching treatment of DMD.

  8. Cell phones and tumor: Still in no man′s land

    Directory of Open Access Journals (Sweden)

    D R Kohli

    2009-01-01

    Full Text Available The use of cell phones is increasing worldwide at a phenomenal pace. While cellular communication has dramatically influenced our lifestyle, its impact on human health has not been completely assessed. Widespread concern continues in the community about the deleterious effects of radiofrequency radiations (with which cell phones operate on human tissues and the subsequent potential for carcinogenesis. A detailed survey of published studies researching this question was done in preparation of this manuscript. Included in the survey were case reports, in vitro studies, population based retrospective studies and other investigations. The database of indexed journals was searched for key words like ′cell phone′, ′radiation′, ′cancer′ and ′radio waves′. Guidelines issued by the World Health Organization, federal and technical authorities, Institute of Electrical and Electronic Engineers and the International Commission for Non-Ionizing Radiation Protection were reviewed. The evaluation of current evidence provided by various studies to suggest the possible carcinogenic potential of radiofrequency radiation is inconclusive. This risk assumes significance in light of the burgeoning number of people who are continually exposed to the high frequency radiation from cell phones and towers that serve as receiving and transmitting stations. The aim of this review is to identify limitations in past studies, present available data for consideration, and identify gaps in the current knowledge base. This will provide impetus and direction for further research and allow informed decisions pertaining to cell phone use to be made.

  9. The effect of cell phone use on postural balance and mobility in older compared to young adults.

    Science.gov (United States)

    Laatar, Rabeb; Kachouri, Hiba; Borji, Rihab; Rebai, Haithem; Sahli, Sonia

    2017-02-24

    Cell phone use is considered as an essential part of everyday life saturating all age groups and demographics. This study aimed to explore the effect of various cell phone functions on postural control and mobility in the elderly. Twenty healthy older (mean age 72.5±2.9) and twenty young (26.3±2.8) adults participated in this study. Postural balance was assessed by measuring the center of pressure (CoP) displacement with (talking on a cell phone (CONVERSE), dialing a number (DIAL) and listening to music (MUSIC)) and without cell phone use. Mobility was assessed by the Timed Up and Go Test (TUGT). Results showed that for both groups, the CoP parameters increased significantly during the CONVERSE (pphone use impairs similarly standing postural balance of elderly and young adults. Interestingly, in the elderly, all cell phone functions used altered mobility with the dialing function causing the largest mobility deterioration.

  10. Performance Analysis of Cell-Phone Worm Spreading in Cellular Networks through Opportunistic Communications

    Directory of Open Access Journals (Sweden)

    YAHUI, W.

    2012-05-01

    Full Text Available Worms spreading directly between cell-phones over short-range radio (Bluetooth, WiFi, etc. are increasing rapidly. Communication by these technologies is opportunistic and has very close relation with the social characteristics of the phone carriers. In this paper, we try to evaluate the impact of different characteristics on the spreading performance of worms. On the other hand, the behaviors of worms may have certain impact, too. For example, worms may make phones be completely dysfunctional and these phones can be seen as killed. We study the impact of the killing speed. Using the Markov model, we propose some theoretical models to evaluate the spreading performance in different cases. Simulation results show the accuracy of our models. Numerical results show that if users do not believe the data coming from others easily, the worms may bring less damage. Surprisingly, if the users are more willing to install the anti-virus software, the worms may bring bigger damage when the software becomes to be outdated with high probability. Though the worms can bring big damage on the network temporarily by killing phones rapidly, numerical results show that this behavior may decrease the total damage in the long time. Therefore, killing nodes more rapidly may be not optimal for worms.

  11. Digital Devices, Distraction, and Student Performance: Does In-Class Cell Phone Use Reduce Learning?

    Science.gov (United States)

    Duncan, Douglas K.; Hoekstra, Angel R.; Wilcox, Bethany R.

    2012-01-01

    The recent increase in use of digital devices such as laptop computers, iPads, and web-enabled cell phones has generated concern about how technologies affect student performance. Combining observation, survey, and interview data, this research assesses the effects of technology use on student attitudes and learning. Data were gathered in eight…

  12. An Investigation on Changing Behaviours of University Students Switching from Using Classical Cell Phones to Smartphones

    Science.gov (United States)

    Arslan, Yusuf

    2016-01-01

    In this study, it was tried to comprehend whether there occur any changes in behaviours of university students switching from classical cell phones to smartphones. The investigation was carried out according to quantitative research method. Questionnaire was employed as data collection tool. The datum of the study was limited with the information…

  13. Cell Phone Methodology for Research and Service with High Risk Mothers and Children

    Science.gov (United States)

    Lanzi, Robin Gaines; Ramey, Sharon Landesman; Lefever, Jennifer Burke; Guest, Kristi Carter; Atwater, Jane; Hughes, Kere

    2007-01-01

    Cell phones afford a set of distinctive advantages for gathering information on daily patterns of behavior, establishing relationships, maintaining contact, and providing professional expertise to participants in a wide array of programs, including intervention, treatment, and service. This paper presents new findings about innovative applications…

  14. Digital Devices, Distraction, and Student Performance: Does In-Class Cell Phone Use Reduce Learning?

    Science.gov (United States)

    Duncan, Douglas K.; Hoekstra, Angel R.; Wilcox, Bethany R.

    2012-01-01

    The recent increase in use of digital devices such as laptop computers, iPads, and web-enabled cell phones has generated concern about how technologies affect student performance. Combining observation, survey, and interview data, this research assesses the effects of technology use on student attitudes and learning. Data were gathered in eight…

  15. Bring-Your-Own-Device: Turning Cell Phones into Forces for Good

    Science.gov (United States)

    Imazeki, Jennifer

    2014-01-01

    Over the last few years, classroom response systems (or "clickers") have become increasingly common. Although most systems require students to use a standalone handheld device, bring-your-own-device (BYOD) systems allow students to use devices they already own (e.g., a cell phone, tablet or laptop) to submit responses via text message or…

  16. Disentangling the influence of cell phone usage in the dilemma zone: An econometric approach.

    Science.gov (United States)

    Eluru, Naveen; Yasmin, Shamsunnahar

    2016-11-01

    This paper focuses on developing an analysis framework to study the impact of cell phone treatment (cell phone type and call status) on driver behavior in the presence of a dilemma zone. Specifically, we examine how the treatment influences the driver maneuver decision at the intersection (stop or cross) and the eventual success of the maneuver. For a stop maneuver, success is defined as stopping before the stop line. Similarly, for a cross maneuver, success is defined as clearing the intersection safely before the light turns red. The eventual success or failure of the driver's decision process is dependent on the factors that affected the maneuver decision. Hence it is important to recognize the interconnectedness of the stop or cross decision with its eventual success (or failure). Toward this end, we formulate and estimate a joint framework to analyze the stop/cross decision with its eventual success (or failure) simultaneously. The study is conducted based on driving simulator data provided online for the 2014 Transportation Research Board Data Contest at http://depts.washington.edu/hfsm/upload.php. The model is estimated to analyze drivers' behavior at the onset of yellow by employing exogenous variables from three broad categories: driver characteristics, cell phone attributes and driving attributes. We also generate probability surfaces to identify dilemma zone distribution associated with different cell phone treatment types. The plots clearly illustrate the impact of various cellphone treatments on driver dilemma zone behavior.

  17. Using a Cell Phone to Investigate the Skin Depth Effect in Salt Water

    Science.gov (United States)

    Rayner, John

    2017-01-01

    This paper describes an experimental investigation of the skin depth effect for electromagnetic waves in salt water using a cell phone that is immersed to a critical depth where it no longer responds when called. We show that this critical depth is directly proportional to the theoretical skin depth for a range of salt concentrations.

  18. Experiments Using Cell Phones in Physics Classroom Education: The Computer-Aided "g" Determination

    Science.gov (United States)

    Vogt, Patrik; Kuhn, Jochen; Muller, Sebastian

    2011-01-01

    This paper continues the collection of experiments that describe the use of cell phones as experimental tools in physics classroom education. We describe a computer-aided determination of the free-fall acceleration "g" using the acoustical Doppler effect. The Doppler shift is a function of the speed of the source. Since a free-falling objects…

  19. Using a Cell Phone to Investigate the Skin Depth Effect in Salt Water

    Science.gov (United States)

    Rayner, John

    2017-02-01

    This paper describes an experimental investigation of the skin depth effect for electromagnetic waves in salt water using a cell phone that is immersed to a critical depth where it no longer responds when called. We show that this critical depth is directly proportional to the theoretical skin depth for a range of salt concentrations.

  20. Cell Phone Methodology for Research and Service with High Risk Mothers and Children

    Science.gov (United States)

    Lanzi, Robin Gaines; Ramey, Sharon Landesman; Lefever, Jennifer Burke; Guest, Kristi Carter; Atwater, Jane; Hughes, Kere

    2007-01-01

    Cell phones afford a set of distinctive advantages for gathering information on daily patterns of behavior, establishing relationships, maintaining contact, and providing professional expertise to participants in a wide array of programs, including intervention, treatment, and service. This paper presents new findings about innovative applications…

  1. Skeletal Muscle Satellite Cell Activation Following Cutaneous Burn in Rats

    Science.gov (United States)

    2013-12-01

    Satellite cell isolation and culture Satellite cells were isolated similar as described by Allen et al. [30]. Following euthanasia , muscles were...satellite cell cultures. Methods Cell Biol 1997;52:155–76. [31] Tatsumi R, Liu X, Pulido A, Morales M, Sakata T, Dial S, Hattori A, Ikeuchi Y, Allen RE

  2. Windows Phone 7智能手机的取证%Cell Forensics on Smart Phone Installed Windows Phone 7 System

    Institute of Scientific and Technical Information of China (English)

    姚伟; 沙晶

    2014-01-01

    作为新兴的智能手机,Windows Phone手机呈稳步发展趋势,并越来越受到人们的关注.在介绍了WindowsPhone 7手机的系统架构和安全模型后,就取证遇到的问题详细地描述了取证方式,探讨了如何对Windows Phone 7智能手机进行取证.通过使用原生级方法和Windows Phone SDK访问Window Phone 7内核和其他数据来获得手机的有价值信息,同时通过一系列工具来分析手机上的文件.结果表明,能够从Windows Phone 7手机中有效寻找到短信、电子邮件、社交活动等证据资料.

  3. Effects of Cell Phone Radiofrequency Signal Exposure on Brain Glucos Metabolism

    Energy Technology Data Exchange (ETDEWEB)

    Volkow, N.D.; Wang, G.; Volkow, N.D.; Tomasi, D.; Wang, G.-J.; Vaska, P.; Fowler, J.S.; Telang, F.; Alexoff, D.; Logan, J.; Wong, C.

    2011-03-01

    The dramatic increase in use of cellular telephones has generated concern about possible negative effects of radiofrequency signals delivered to the brain. However, whether acute cell phone exposure affects the human brain is unclear. To evaluate if acute cell phone exposure affects brain glucose metabolism, a marker of brain activity. Randomized crossover study conducted between January 1 and December 31, 2009, at a single US laboratory among 47 healthy participants recruited from the community. Cell phones were placed on the left and right ears and positron emission tomography with ({sup 18}F)fluorodeoxyglucose injection was used to measure brain glucose metabolism twice, once with the right cell phone activated (sound muted) for 50 minutes ('on' condition) and once with both cell phones deactivated ('off' condition). Statistical parametric mapping was used to compare metabolism between on and off conditions using paired t tests, and Pearson linear correlations were used to verify the association of metabolism and estimated amplitude of radiofrequency-modulated electromagnetic waves emitted by the cell phone. Clusters with at least 1000 voxels (volume >8 cm{sup 3}) and P < .05 (corrected for multiple comparisons) were considered significant. Brain glucose metabolism computed as absolute metabolism ({micro}mol/100 g per minute) and as normalized metabolism (region/whole brain). Whole-brain metabolism did not differ between on and off conditions. In contrast, metabolism in the region closest to the antenna (orbitofrontal cortex and temporal pole) was significantly higher for on than off conditions (35.7 vs 33.3 {micro}mol/100 g per minute; mean difference, 2.4 [95% confidence interval, 0.67-4.2]; P = .004). The increases were significantly correlated with the estimated electromagnetic field amplitudes both for absolute metabolism (R = 0.95, P < .001) and normalized metabolism (R = 0.89; P < .001). In healthy participants and compared with no

  4. Teen Drivers' Perceptions of Inattention and Cell Phone Use While Driving.

    Science.gov (United States)

    McDonald, Catherine C; Sommers, Marilyn S

    2015-01-01

    Inattention to the roadway, including cell phone use while driving (cell phone calls, sending and reading texts, mobile app use, and Internet use), is a critical problem for teen drivers and increases risk for crashes. Effective behavioral interventions for teens are needed in order to decrease teen driver inattention related to cell phone use while driving. However, teens' perceptions of mobile device use while driving is a necessary component for theoretically driven behavior change interventions. The purpose of this study was to describe teen drivers' perceptions of cell phone use while driving in order to inform future interventions to reduce risky driving. We conducted 7 focus groups with a total of 30 teen drivers, ages 16-18, licensed for ≤ 1 year in Pennsylvania. The focus group interview guide and analysis were based on the Theory of Planned Behavior, identifying the attitudes, perceived behavioral control, and norms about inattention to the roadway. Directed descriptive content analysis was used to analyze the focus group interviews. All focus groups were coded by 2 research team members and discrepancies were reconciled. Themes were developed based on the data. Teens had a mean age of 17.39 (SD = 0.52), mean length of licensure of 173.7 days (SD = 109.2; range 4-364), were 50% male and predominately white (90%) and non-Hispanic (97%). From the focus group data, 3 major themes emerged: (1) Recognizing the danger but still engaging; (2) Considering context; and (3) Formulating safer behaviors that might reduce risk. Despite recognizing that handheld cell phone use, texting, and social media app use are dangerous and distracting while driving, teens and their peers often engaged in these behaviors. Teens described how the context of the situation contributed to whether a teen would place or answer a call, write or respond to a text, or use a social media app. Teens identified ways in which they controlled their behaviors, although some still drew

  5. Cellular Phone Towers, Cell phone sectors, Published in 2008, 1:2400 (1in=200ft) scale, Hodgeman County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Not Provided information as of 2008. It is described as...

  6. Cellular Phone Towers, cell phone towers, Published in 2008, 1:2400 (1in=200ft) scale, Hodgeman County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Not Provided information as of 2008. It is described as...

  7. Isolation and Culture of Satellite Cells from Mouse Skeletal Muscle.

    Science.gov (United States)

    Musarò, Antonio; Carosio, Silvia

    2017-01-01

    Skeletal muscle tissue is characterized by a population of quiescent mononucleated myoblasts, localized between the basal lamina and sarcolemma of myofibers, known as satellite cells. Satellite cells play a pivotal role in muscle homeostasis and are the major source of myogenic precursors in mammalian muscle regeneration.This chapter describes protocols for isolation and culturing satellite cells isolated from mouse skeletal muscles. The classical procedure, which will be discussed extensively in this chapter, involves the enzymatic dissociation of skeletal muscles, while the alternative method involves isolation of satellite cells from isolated myofibers in which the satellite cells remain in their in situ position underneath the myofiber basal lamina.In particular, we discuss the technical aspect of satellite cell isolation, the methods necessary to enrich the satellite cell fraction and the culture conditions that optimize proliferation and myotube formation of mouse satellite cells.

  8. BMP signaling regulates satellite cell-dependent postnatal muscle growth.

    Science.gov (United States)

    Stantzou, Amalia; Schirwis, Elija; Swist, Sandra; Alonso-Martin, Sonia; Polydorou, Ioanna; Zarrouki, Faouzi; Mouisel, Etienne; Beley, Cyriaque; Julien, Anaïs; Le Grand, Fabien; Garcia, Luis; Colnot, Céline; Birchmeier, Carmen; Braun, Thomas; Schuelke, Markus; Relaix, Frédéric; Amthor, Helge

    2017-08-01

    Postnatal growth of skeletal muscle largely depends on the expansion and differentiation of resident stem cells, the so-called satellite cells. Here, we demonstrate that postnatal satellite cells express components of the bone morphogenetic protein (BMP) signaling machinery. Overexpression of noggin in postnatal mice (to antagonize BMP ligands), satellite cell-specific knockout of Alk3 (the gene encoding the BMP transmembrane receptor) or overexpression of inhibitory SMAD6 decreased satellite cell proliferation and accretion during myofiber growth, and ultimately retarded muscle growth. Moreover, reduced BMP signaling diminished the adult satellite cell pool. Abrogation of BMP signaling in satellite cell-derived primary myoblasts strongly diminished cell proliferation and upregulated the expression of cell cycle inhibitors p21 and p57 In conclusion, these results show that BMP signaling defines postnatal muscle development by regulating satellite cell-dependent myofiber growth and the generation of the adult muscle stem cell pool. © 2017. Published by The Company of Biologists Ltd.

  9. Exposure to Cell Phone Radiation Up-Regulates Apoptosis Genes in Primary Cultures of Neurons and Astrocytes

    OpenAIRE

    Zhao, Tian-Yong; Zou, Shi-Ping; Pamela E Knapp

    2006-01-01

    The health effects of cell phone radiation exposure are a growing public concern. This study investigated whether expression of genes related to cell death pathways are dysregulated in primary cultured neurons and astrocytes by exposure to a working GSM (Global System for Mobile Communication) cell phone rated at a frequency of 1900 MHz. Primary cultures were exposed to cell phone emissions for 2 hrs. We used array analysis and real-time RT-PCR to show up-regulation of caspase-2, caspase-6 an...

  10. Proliferation conditions for human satellite cells. The fractional content of satellite cells

    DEFF Research Database (Denmark)

    Gaster, M; Beck-Nielsen, H; Schrøder, H D

    2001-01-01

    the fraction of Sc in culture. Evaluation of different culture conditions allowed us to find proliferation conditions preferentially for Sc: a) Sc should be cultured on surfaces coated with ECM-gel. b) Primary cell culture should be inoculated in DMEM supplemented with 10% fetal calf serum to increase cell......Primary satellite cell cultures have become an important tool as a model system for skeletal muscles. A common problem in human satellite cell culturing is fibroblast overgrowth. We combined N-CAM (Leu19) immunocytochemical staining of satellite cells (Sc) with stereological methods to estimate...... adherence. c) Change of media to DMEM supplemented with 2% Ultroser-G and 2% FCS after 24 h.d) Before subcultivation, cells should be preplated for 30 min. The fractional content of Sc in passage four when applying this method of cultivation was 0.82 +/- 0.07 (mean +/- SE, N = 10). Our method enabled us...

  11. Cell phone recycling experiences in the United States and potential recycling options in Brazil.

    Science.gov (United States)

    Silveira, Geraldo T R; Chang, Shoou-Yuh

    2010-11-01

    This paper presents an overview of cell phone recycling programs currently available in the United States. At the same time, it also provides analyses of the current recycling situation and possible recycling alternatives for Brazil. Although there are several recycling options in the United States, collection rates are still only 10% of all potential devices because customers are not aware of these possibilities. The whole system is financially based on reselling refurbished cell phones and recycled materials to developing countries which represent an effective and strong market. Several recyclers offer funds to collection partners who are either charities or who work with charities while obtaining the materials that they need in order to run their operations. A mobile phone recycling system for Brazil considering the United States experience and the Extended Producer Responsibility (EPR) principle is suggested. A deposit/refund/advance-recycling fee is proposed which might be implemented as a voluntary industrial initiative managed by PRO Brazil, a producer responsibility organization. One widespread public-private agreement will integrate all mobile phone stakeholders, and environmental education actions and promotional events will promote citizen's participation.

  12. Evaluation of the Interference of the Microwave Radiation Emitted from GSM Mobile Phones on the Performance of Cell Counters

    Directory of Open Access Journals (Sweden)

    Bahaedini ,N.

    2009-01-01

    Full Text Available Background and Objectives: Incidents related to electromagneticinterference with medical devices have been reported over the past decades.It has also been indicated that the microwave radiation emitted from mobilephones interferes with the operation of medical devices; therefore, this studyaimed at testing the interference by GSM mobile phones with cell counters.Material and Methods: We did this experimental Study on thirty-twoheparinized blood samples of 32 healthy individuals Selected randomly. TheCell Counting was Carried out in the presence of Electro magnetic fieldproduced by three Cell phones with different levels of SAR (Low,intermediate and High and without being in electromagnetic field.Statistical tests were used to analyze the data (p<0.05.Results: Microwave radiation emitted from cell phones, regardless of theirSAR, interferes with the proper operation of cell Counter. This interferenceleads to false Counting.Conclusion: As mobile phones emit microwave radiation in an isotropicmanner, keeping mobile phones at a safe distance, 15cm, from medicalequipments will be necessary. These observations confirm the need for somerestrictions of mobile phone use in hospitals and medical laboratories.Key words: Interference, Cell Counters, Mobile Phone, MicrowaveRadiation

  13. Evaluation of the Accuracy of a Triaxial Accelerometer Embedded into a Cell Phone Platform for Measuring Physical Activity.

    Science.gov (United States)

    Manohar, C U; McCrady, S K; Fujiki, Y; Pavlidis, I T; Levine, J A

    2011-12-20

    Physical activity is important in health and weight management. Several cell phone platforms integrate an accelerometer onto the motherboard. Here we tested the validity of the cell phone accelerometer to assess physical activity in a controlled laboratory setting. 31 subjects wore the cell phone on their waist along with the validated Physical Activity Monitoring System (PAMS) with different body postures and during graded walking. Energy expenditure was measured using indirect calorimetry. 11 subjects also wore the iPhone at different locations such as arm, hand, pant pocket, etc. The cell phone accelerometer was accurate and precise compared to the PAMS, with an intra-class correlation coefficient (r(2)> 0.98). The cell phone accelerometer showed excellent sequential increases with increased in walking velocity and energy expenditure (r(2)>0.9). An accelerometer embedded into a cell phone was accurate and reliable in measuring and quantifying physical activity in the laboratory setting. Data from free-living users shows promise for deployment of a comprehensive integrated physical activity promoting and weight loss platform using such mobile technologies.

  14. Women's adult romantic attachment style and communication by cell phone with romantic partners.

    Science.gov (United States)

    Weisskirch, Robert S

    2012-08-01

    Cell phones have become important communication media for individuals in romantic relationships. The frequency of and methods used for communication may vary by adults' style of romantic attachment. Female university students (N = 31) currently in romantic relationships responded to a questionnaire. They estimated the frequency of calls and text messages received from and made to their romantic partners and completed the Experiences in Close Relationships-Revised instrument, a measure of attachment anxiety and avoidance. Also, the participants reviewed their cell phones' memories and provided accurate frequency of communication to and from the romantic partner. Attachment anxiety was associated with more estimated text messages sent to and received from the romantic partners and actual text messages sent to and received from the romantic partners. Attachment avoidance was associated (r = -.38) with fewer estimated calls made to the romantic partners and fewer actual calls made to the romantic partners (r = -.34).

  15. A Mathematical Model for Energy Consequences of the Cell Phone Revolution

    Institute of Scientific and Technical Information of China (English)

    于晶; 周键聪

    2009-01-01

    In the modern tim e,cell phone reduces the cost of important inform a-tion,p lays a cruc ial role in both fac ilitate international and dom estic trades,as well as impacts the effic iency ofm ed ical service.Consider a c ity and estim ate from ava ilab le data the numberH of house-holds,w ith m m embers each,that in the past were serviced by land lines.Now,suppose that som e land lines are rep laced by cell phones.W e model theconsequences of th is change for electric ity utilization in the c ity,during the...

  16. Integrating cell phones and mobile technologies into public health practice: a social marketing perspective.

    Science.gov (United States)

    Lefebvre, Craig

    2009-10-01

    Mobile communications are being used for many purposes, from instant messaging (IM), mobile or microblogging (Twitter), social networking sites (Facebook, MySpace), e-mail to basic voicemail. A brief background on cell phone and mobile technology use in public health is reviewed. The focus of the article is framing the use of mobile technologies in public health from a social marketer's perspective--using the 4 Ps marketing mix as a guide.

  17. Adapting to Student Learning Styles: Using Cell Phone Technology in Undergraduate Science Instruction

    OpenAIRE

    Richard Pennington; Julia Paredes; Mai Yin Tsoi; Candace Timpte; Deborah Sauder; David Pursell

    2010-01-01

    Students of science traditionally make 3x5 flash cards to assist learning nomenclature, structures, and reactions. Advances in educational technology have enabled flashcards viewed on computers, offering an endless array of drilling and feedback opportunities for students. The current generation of students is less inclined to use computers, but they use their cell phones 24 hours a day. This report outlines these trends and an even more recent educational technology initiative, that of using...

  18. Talking about killing: Cell Phones, Collective Action, and Insurgent Violence in Iraq

    Science.gov (United States)

    2011-05-31

    technology, insurgency, collective action Jacob Shapiro, Nils Weidmann Harvard University Office of Sponsored Research 1350 Massachusetts Ave. Holyoke 727...at the district level changes as a result of the introduction of new cell phone towers. Second, using a novel identification strategy, we examine how... identification strategy, we examine how insurgent operation in the tower’s vicinity is affected by the introduction of coverage. Taken together, our

  19. Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis with focus on male reproductive system

    OpenAIRE

    Kesari Kavindra K; Desai Nisarg R; Agarwal Ashok

    2009-01-01

    Abstract Hazardous health effects stemming from exposure to radiofrequency electromagnetic waves (RF-EMW) emitted from cell phones have been reported in the literature. However, the cellular target of RF-EMW is still controversial. This review identifies the plasma membrane as a target of RF-EMW. In addition, the effects of RF-EMW on plasma membrane structures (i.e. NADH oxidase, phosphatidylserine, ornithine decarboxylase) and voltage-gated calcium channels are discussed. We explore the dist...

  20. Cell Phone Internet Access, Online Sexual Solicitation, Partner Seeking, and Sexual Risk Behavior among Adolescents

    OpenAIRE

    Rice, Eric; Winetrobe, Hailey; Holloway, Ian W.; Montoya, Jorge; Plant, Aaron; Kordic, Timothy

    2014-01-01

    Online partner seeking is associated with sexual risk behavior among young adults (specifically men who have sex with men), but this association has yet to be explored among a probability sample of adolescents. Moreover, cell phone internet access and sexual risk taking online and offline have not been explored. A probability sample (N = 1,831) of Los Angeles Unified School District high school students was collected in 2011. Logistic regression models assessed relationships between specific ...

  1. Comparing Cell Phone-Based and Traditional Lecture-Based Teaching Methods' Effects on Agricultural Students' Learning

    National Research Council Canada - National Science Library

    Abdolhamid Papzan; Adel Sulaimany

    2010-01-01

    ... research was conducted to examine the effect of teaching via cell phone on students learning in Khooshehaye Zarin agricultural school in Rawansar, Kermanshah province, and comparing it with traditional lecture method...

  2. Location Dependency and Antenna/Body/Sensor-Lead Interaction Effects in a Cell-Phone Based GSM 1800 Telemedicine Link

    National Research Council Canada - National Science Library

    Troulis, S

    2001-01-01

    The error-free requirement of today's cell-phone based telemedicine systems demands investigations into the potential causes of service degradation, Measuring the Received Signal Strength Indication (RSSI...

  3. Digital Devices, Distraction and Student Performance - Does Cell Phone Use Reduce Learning?

    Science.gov (United States)

    Duncan, Douglas K.; Hoekstra, A. R.; Wilcox, B. R.

    2012-01-01

    The recent increase in the use of digital devices such as laptop computers, iPads and web-enabled cell phones has generated concern about how technologies affect student performance. Combining observation, survey, and interview data, this research assesses the effects of technology use for student attitudes and learning. Data were gathered in eight introductory science courses at one large public university in 2010-2011. Results show a significant negative correlation between in-class cell phone use and overall course grades, corresponding to a drop of 0.36 ± 0.08 on a 4-point scale where 4.0 = A. These findings are consistent with recent research[1] suggesting students cannot multi-task nearly as effectively as they think they can. While 75% of students reported regular cell phone use, observation data suggests undergraduates typically under-report the frequency of in-class digital device use. [1] Ophir, E., Nass, C. and A.D. Wagner. 2009. "Cognitive Control in Media Multi-Taskers.” Proceedings of the National Academy of Sciences, 106: 15583-15587.

  4. Effects of cell phone use on semen parameters: Results from the MARHCS cohort study in Chongqing, China.

    Science.gov (United States)

    Zhang, Guowei; Yan, Huan; Chen, Qing; Liu, Kaijun; Ling, Xi; Sun, Lei; Zhou, Niya; Wang, Zhi; Zou, Peng; Wang, Xiaogang; Tan, Lu; Cui, Zhihong; Zhou, Ziyuan; Liu, Jinyi; Ao, Lin; Cao, Jia

    2016-05-01

    Epidemiological and experimental evidence for detrimental effects of cell phone use on semen quality is still equivocal. And that recruiting participants from infertility clinic not from general population may raise the possibility of a selection bias. To investigate effects of cell phone use on semen parameters in a general population,We screened and documented the cell phone use information of 794 young men from the Male Reproductive Health in Chongqing College students (MARHCS) cohort study in 2013, followed by 666 and 568 in 2014 and 2015, respectively. In the univariate regression analyses, we found that the daily duration of talking on the cell phone was significantly associated with decreased semen parameters, including sperm concentration [β coefficient=-6.32% per unit daily duration of talking on the cell phone (h); 95% confidence interval (CI), -11.94, -0.34] and total sperm count (-8.23; 95% CI, -14.38, -1.63) in 2013; semen volume (-8.37; 95% CI, -15.93, -0.13) and total sperm count (-16.59; 95% CI, -29.91, -0.73) in 2015]. Internet use via cellular networks was also associated with decreased sperm concentration and total sperm counts in 2013 and decreased semen volume in 2015. Multivariate analyses were used to adjust for the effects of potential confounders, and significant negative associations between internet use and semen parameters remained. Consistent but nonsignificant negative associations between talking on the cell phone and semen parameters persisted throughout the three study years, and the negative association was statistically significant in a mixed model that considered all three years of data on talking on the cell phone and semen quality. Our results showed that certain aspects of cell phone use may negatively affect sperm quality in men by decreasing the semen volume, sperm concentration, or sperm count, thus impairing male fertility.

  5. Sleep Quality in Medical Students; the Impact of Over-Use of Mobile Cell-Phone and Social Networks.

    Science.gov (United States)

    Mohammadbeigi, Abolfazl; Absari, Rozita; Valizadeh, Farzaneh; Saadati, Mohammadreza; Sharifimoghadam, Soroush; Ahmadi, Ali; Mokhtari, Mohsen; Ansari, Hossein

    2016-01-01

    Poor sleep quality is closely associated with lifestyle habits including use of mobile cell-phones.This study aimed to identify the relationship between sleep quality due to abuse in mobile cell-phones and engagement in social networks. This cross-sectional study was conducted on 380 undergraduate students selected by proportional stratified sampling in Qom, Iran in 2015. Data were collected by two standard questionnaire including Cell-Phone Over-Use Scale (COS) and Pittsburgh sleep quality questionnaire beside the status of usage in cell-phone social networks. T-test, chi-square, Pearson correlation coefficient and multivariate logistic regression were used in data analysis. The mean age of participants was 21.8 ±3.2 yr, 69.1% were female, and 11.7% were married. The mean of COS and sleep quality scores were 48.18 ±17.5 and 5.38 ±2.31, respectively. The prevalence of over-use of cell phone was 10.7% (CI 0.95; 8.8%, 12.6%) and the prevalence of poor sleep quality was 61.7% (CI 0.95; 57.1%, 66.3%). The mean of all aspects and total score of sleep quality showed a direct significant association by cell-phone addiction score except sleep duration score that was inversely. Based on multivariate analysis affected to cell-phone addiction, being male gender and studying in general physician level are the most important predictors of poor sleep quality. Over use of internet and social networks via smart phones is related to poor sleep quality and quantity. Predefined sport programs, educational, cultural, and interesting entertainment are the essential needs for all medical students. These interventions are more important especially for male students who have longer educational.

  6. Exposure limits: the underestimation of absorbed cell phone radiation, especially in children.

    Science.gov (United States)

    Gandhi, Om P; Morgan, L Lloyd; de Salles, Alvaro Augusto; Han, Yueh-Ying; Herberman, Ronald B; Davis, Devra Lee

    2012-03-01

    The existing cell phone certification process uses a plastic model of the head called the Specific Anthropomorphic Mannequin (SAM), representing the top 10% of U.S. military recruits in 1989 and greatly underestimating the Specific Absorption Rate (SAR) for typical mobile phone users, especially children. A superior computer simulation certification process has been approved by the Federal Communications Commission (FCC) but is not employed to certify cell phones. In the United States, the FCC determines maximum allowed exposures. Many countries, especially European Union members, use the "guidelines" of International Commission on Non-Ionizing Radiation Protection (ICNIRP), a non governmental agency. Radiofrequency (RF) exposure to a head smaller than SAM will absorb a relatively higher SAR. Also, SAM uses a fluid having the average electrical properties of the head that cannot indicate differential absorption of specific brain tissue, nor absorption in children or smaller adults. The SAR for a 10-year old is up to 153% higher than the SAR for the SAM model. When electrical properties are considered, a child's head's absorption can be over two times greater, and absorption of the skull's bone marrow can be ten times greater than adults. Therefore, a new certification process is needed that incorporates different modes of use, head sizes, and tissue properties. Anatomically based models should be employed in revising safety standards for these ubiquitous modern devices and standards should be set by accountable, independent groups.

  7. Please silence your cell phone: Your ringtone captures other people′s attention

    Directory of Open Access Journals (Sweden)

    Jan P Röer

    2014-01-01

    Full Text Available Ringtones are designed to draw attention away from on-going activities. In the present study, it was investigated whether the disruptive effects of a ringing cell phone on short-term memory are inevitable or become smaller as a function of exposure and whether (self- relevance plays a role. Participants performed a serial recall task either in silence or while task-irrelevant ringtones were presented. Performance was worse when a ringing phone had to be ignored, but gradually recovered compared with the quiet control condition with repeated presentation of the distractor sound. Whether the participant′s own ringtone was played or that of a yoked-control partner did not affect performance and habituation rate. The results offer insight into auditory distraction by highly attention-demanding distractors and recovery therefrom. Implications for work environments and other applied settings are discussed.

  8. Satellite Cells in Muscular Dystrophy - Lost in Polarity.

    Science.gov (United States)

    Chang, Natasha C; Chevalier, Fabien P; Rudnicki, Michael A

    2016-06-01

    Recent findings employing the mdx mouse model for Duchenne muscular dystrophy (DMD) have revealed that muscle satellite stem cells play a direct role in contributing to disease etiology and progression of DMD, the most common and severe form of muscular dystrophy. Lack of dystrophin expression in DMD has critical consequences in satellite cells including an inability to establish cell polarity, abrogation of asymmetric satellite stem-cell divisions, and failure to enter the myogenic program. Thus, muscle wasting in dystrophic mice is not only caused by myofiber fragility but is exacerbated by intrinsic satellite cell dysfunction leading to impaired regeneration. Despite intense research and clinical efforts, there is still no effective cure for DMD. In this review we highlight recent research advances in DMD and discuss the current state of treatment and, importantly, how we can incorporate satellite cell-targeted therapeutic strategies to correct satellite cell dysfunction in DMD.

  9. Myogenic skeletal muscle satellite cells communicate by tunnelling nanotubes.

    Science.gov (United States)

    Tavi, Pasi; Korhonen, Topi; Hänninen, Sandra L; Bruton, Joseph D; Lööf, Sara; Simon, Andras; Westerblad, Håkan

    2010-05-01

    Quiescent satellite cells sit on the surface of the muscle fibres under the basal lamina and are activated by a variety of stimuli to disengage, divide and differentiate into myoblasts that can regenerate or repair muscle fibres. Satellite cells adopt their parent's fibre type and must have some means of communication with the parent fibre. The mechanisms behind this communication are not known. We show here that satellite cells form dynamic connections with muscle fibres and other satellite cells by F-actin based tunnelling nanotubes (TNTs). Our results show that TNTs readily develop between satellite cells and muscle fibres. Once developed, TNTs permit transport of intracellular material, and even cellular organelles such as mitochondria between the muscle fibre and satellite cells. The onset of satellite cell differentiation markers Pax-7 and MyoD expression was slower in satellite cells cultured in the absence than in the presence of muscle cells. Furthermore physical contact between myofibre and satellite cell progeny is required to maintain subtype identity. Our data establish that TNTs constitute an integral part of myogenic cell communication and that physical cellular interaction control myogenic cell fate determination.

  10. In-person contact begets calling and texting: interpersonal motives for cell phone use, face-to-face interaction, and loneliness.

    Science.gov (United States)

    Jin, Borae; Park, Namkee

    2010-12-01

    This study examined how cell-phone use is related to interpersonal motives for using cell phones, face-to-face communication, and loneliness. A survey of 232 college students who owned a cell phone revealed that affection and inclusion were relatively strong motivations for using voice calls and text messaging, and that interpersonal motives were positively related to the amount of cell-phone use, including calling and texting. The amount of face-to-face interaction was positively associated with the participants' cell-phone use and their interpersonal motives for using cell phones: the more the participants engaged in face-to-face interaction with other people, the higher their motives were and the more frequent cell-phone use was. Loneliness did not have a direct relation to cell-phone use. Instead, the participants with higher levels of loneliness were less likely to engage in face-to-face social interaction, which led them to use cell phones less and to be less motivated to use cell phones for interpersonal purposes.

  11. Survival Assessment of Mouse Preimplantation Embryos After Exposure to Cell Phone Radiation

    Science.gov (United States)

    Safian, Fereshteh; Khalili, Mohammad Ali; Khoradmehr, Arezoo; Anbari, Fatemeh; Soltani, Saeedeh; Halvaei, Iman

    2016-01-01

    Background: Using cellular phone has rapidly increased all over the world. Also, the concern on the possible health hazards of electromagnetic fields (EMF) induced from cell phones to reproduction has been growing in many countries. The aim of this study was to assess the consequences and effects of exposure to the cell phone radiation on the quality and survival rates of preimplantation embryos in mice. Methods: A total of 40 mice (20 females and 20 males), 6 weeks old and sexually mature BALB/c, were used for control and experimental groups. The ovary burses were removed and the zygotes were dissected in the morning after mating. Next, 2-cell embryos were divided into two groups of control (n=150) and experimental (n=150). EMF (900–1800 MHz) was used for four days in experimental group for 30 min/day in culture at 37°C in a CO 2 incubator. The quality of embryos was recorded daily and the fluorescent staining was used for identification of viable blastocysts. All data were compared by Student’s t-test and Mann-Whitney test (p<0.05). Results: The rate of embryo survival to the blastocysts stage was similar in both groups. However, the percentage of dead embryos at the 2-cell stage was significantly higher in EMF-exposed group compared with controls (p=0.03). Also, the loss of cell viability significantly increased in experimental blastocysts (p=0.002). Conclusion: The normal embryonic development up to the blastocyst stage indicates that EMF-exposure commonly did not have adverse effect on embryo development in mice. But, it caused loss of blastocysts cell viability. PMID:27478766

  12. Functional Overload Enhances Satellite Cell Properties in Skeletal Muscle

    Directory of Open Access Journals (Sweden)

    Shin Fujimaki

    2016-01-01

    Full Text Available Skeletal muscle represents a plentiful and accessible source of adult stem cells. Skeletal-muscle-derived stem cells, termed satellite cells, play essential roles in postnatal growth, maintenance, repair, and regeneration of skeletal muscle. Although it is well known that the number of satellite cells increases following physical exercise, functional alterations in satellite cells such as proliferative capacity and differentiation efficiency following exercise and their molecular mechanisms remain unclear. Here, we found that functional overload, which is widely used to model resistance exercise, causes skeletal muscle hypertrophy and converts satellite cells from quiescent state to activated state. Our analysis showed that functional overload induces the expression of MyoD in satellite cells and enhances the proliferative capacity and differentiation potential of these cells. The changes in satellite cell properties coincided with the inactivation of Notch signaling and the activation of Wnt signaling and likely involve modulation by transcription factors of the Sox family. These results indicate the effects of resistance exercise on the regulation of satellite cells and provide insight into the molecular mechanism of satellite cell activation following physical exercise.

  13. Isolation, Culture and Identification of Porcine Skeletal Muscle Satellite Cells

    Directory of Open Access Journals (Sweden)

    Bo-jiang Li

    2015-08-01

    Full Text Available The objective of this study was to establish the optimum protocol for the isolation and culture of porcine muscle satellite cells. Mononuclear muscle satellite cells are a kind of adult stem cell, which is located between the basal lamina and sarcolemma of muscle fibers and is the primary source of myogenic precursor cells in postnatal muscle. Muscle satellite cells are a useful model to investigate the mechanisms of muscle growth and development. Although the isolation and culture protocols of muscle satellite cells in some species (e.g. mouse have been established successfully, the culture system for porcine muscle satellite cells is very limited. In this study, we optimized the isolation procedure of porcine muscle satellite cells and elaborated the isolation and culture process in detail. Furthermore, we characterized the porcine muscle satellite cells using the immunofluorecence. Our study provides a reference for the isolation of porcine muscle satellite cells and will be useful for studying the molecular mechanisms in these cells.

  14. Satellite cells from dystrophic muscle retain regenerative capacity

    Directory of Open Access Journals (Sweden)

    Luisa Boldrin

    2015-01-01

    Full Text Available Duchenne muscular dystrophy is an inherited disorder that is characterized by progressive skeletal muscle weakness and wasting, with a failure of muscle maintenance/repair mediated by satellite cells (muscle stem cells. The function of skeletal muscle stem cells resident in dystrophic muscle may be perturbed by being in an increasing pathogenic environment, coupled with constant demands for repairing muscle. To investigate the contribution of satellite cell exhaustion to this process, we tested the functionality of satellite cells isolated from the mdx mouse model of Duchenne muscular dystrophy. We found that satellite cells derived from young mdx mice contributed efficiently to muscle regeneration within our in vivo mouse model. To then test the effects of long-term residence in a dystrophic environment, satellite cells were isolated from aged mdx muscle. Surprisingly, they were as functional as those derived from young or aged wild type donors. Removing satellite cells from a dystrophic milieu reveals that their regenerative capacity remains both intact and similar to satellite cells derived from healthy muscle, indicating that the host environment is critical for controlling satellite cell function.

  15. The role of satellite cells in muscle hypertrophy.

    Science.gov (United States)

    Blaauw, Bert; Reggiani, Carlo

    2014-02-01

    The role of satellite cells in muscle hypertrophy has long been a debated issue. In the late 1980s it was shown that proteins remain close to the myonucleus responsible for its synthesis, giving rise to the idea of a nuclear domain. This, together with the observation that during various models of muscle hypertrophy there is an activation of the muscle stem cells, i.e. satellite cells, lead to the idea that satellite cell activation is required for muscle hypertrophy. Thus, satellite cells are not only responsible for muscle repair and regeneration, but also for hypertrophic growth. Further support for this line of thinking was obtained after studies showing that irradiation of skeletal muscle, and therefore elimination of all satellite cells, completely prevented overload-induced hypertrophy. Recently however, using different transgenic approaches, it has become clear that muscle hypertrophy can occur without a contribution of satellite cells, even though in most situations of muscle hypertrophy satellite cells are activated. In this review we will discuss the contribution of satellite cells, and other muscle-resident stem cells, to muscle hypertrophy both in mice as well as in humans.

  16. Assessment of oxidant/antioxidant status in saliva of cell phone users.

    Science.gov (United States)

    Khalil, Ahmad M; Abu Khadra, Khalid M; Aljaberi, Ahmad M; Gagaa, Marwan H; Issa, Hamzah S

    2014-06-01

    Hazardous health effects resulting from exposure to radiofrequency electromagnetic radiation (RF-EMR) emitted from cell phones have been reported in the literature. However, the cellular and molecular targets of RF-EMR are still controversial. The aim of this study was to examine the oxidant/antioxidant status in saliva of cell phone users. Saliva samples collected before using a cell phone as well as at the end of 15 and 30 min calls were tested for two commonly used oxidative stress biomarkers: malondialdehyde (MDA) and 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-Oxo-dG). The 8-oxo-dG levels were determined by enzyme-linked immunosorbent (ELISA) competitive assay, while the MDA levels were measured using the OxiSelect MDA adduct ELISA Kit. The antioxidant capacity of the saliva was evaluated using the oxygen radical absorption capacity (ORAC) and the hydroxyl radical averting capacity (HORAC) assays according to the manufacture instructions. The mean 8-oxo-dG and the Bradford protein concentrations (ng/ml and mg/ml, respectively) peaked at 15 min. The levels of HORAC, ORAC and MDA progressively increased with time and reached maximum at 30 min. However, there was no significant effect of talking time on the levels of 8-OxodG and MDA. Similarly, there was no statistically significant effect of talking time on the oxygen and hydroxyl radicals averting capacities, (ORAC) and (HORAC), respectively. These findings suggest that there is no relationship between exposure to radio frequency radiation (RFR) and changes in the salivary oxidant/antioxidant profile.

  17. Pilot study of a cell phone-based exercise persistence intervention post-rehabilitation for COPD

    Directory of Open Access Journals (Sweden)

    Huong Q Nguyen

    2009-08-01

    Full Text Available Huong Q Nguyen1, Dawn P Gill1, Seth Wolpin1, Bonnie G Steele2, Joshua O Benditt11University of Washington, seattle, WA, USA; 2VA Puget Sound Health Care System, Seattle, WA, USAObjective: To determine the feasibility and efficacy of a six-month, cell phone-based exercise persistence intervention for patients with chronic obstructive pulmonary disease (COPD following pulmonary rehabilitation.Methods: Participants who completed a two-week run-in were randomly assigned to either MOBILE-Coached (n = 9 or MOBILE-Self-Monitored (n = 8. All participants met with a nurse to develop an individualized exercise plan, were issued a pedometer and exercise booklet, and instructed to continue to log their daily exercise and symptoms. MOBILE-Coached also received weekly reinforcement text messages on their cell phones; reports of worsening symptoms were automatically flagged for follow-up. Usability and satisfaction were assessed. Participants completed incremental cycle and six minute walk (6MW tests, wore an activity monitor for 14 days, and reported their health-related quality of life (HRQL at baseline, three, and six months.Results: The sample had a mean age of 68 ± 11 and forced expiratory volume in one second (FEV1 of 40 ± 18% predicted. Participants reported that logging their exercise and symptoms was easy and that keeping track of their exercise helped them remain active. There were no differences between groups over time in maximal workload, 6MW distance, or HRQL (p > 0.05; however, MOBILE-Self-Monitored increased total steps/day whereas MOBILE-Coached logged fewer steps over six months (p = 0.04.Conclusions: We showed that it is feasible to deliver a cell phone-based exercise persistence intervention to patients with COPD post-rehabilitation and that the addition of coaching appeared to be no better than self-monitoring. The latter finding needs to be interpreted with caution since this was a purely exploratory study.Trial registration: Clinical

  18. Hadeda: the noisy way to practice spelling vocabulary using a cell phone

    CSIR Research Space (South Africa)

    Butgereit, LL

    2009-05-01

    Full Text Available extensively forget how to spell words or they spell words without vowels or they exchange letters such as “o” (oh) or “l” (ell) with numerals such as “0” (zero) or “1” (one). The objective of Hadeda is to determine if cell phones can be used to assist.... The safety and emotional well being of these minor children was of utmost importance to the Hadeda team. The following steps were taken to ensure that Hadeda did not dispense vocabulary that was not appropriate for these children: 1 Only parents...

  19. Investigating population dynamics of the Kumbh Mela through the lens of cell phone data

    CERN Document Server

    Onnela, Jukka-Pekka

    2015-01-01

    The Kumbh is a religious Hindu festival that has been celebrated for centuries. The 2013 Kumbh Mela, a grander form of the annual Kumbh, was purportedly the largest gathering of people in human history. Many of the participants carried cell phones, making it possible for us to use a data-driven approach to document this magnificent festival. We used Call Detail Records (CDRs) from participants attending the event, a total of 390 million records, to investigate its population dynamics. We report here on some of our preliminary findings.

  20. Self-reported neck symptoms and use of personal computers, laptops and cell phones among Finns aged 18-65.

    Science.gov (United States)

    Korpinen, Leena; Pääkkönen, Rauno; Gobba, Fabriziomaria

    2013-01-01

    The purpose of this study was to investigate the possible relation between self-reported neck symptoms (aches, pain or numbness) and use of computers/cell phones. The study was carried out as a cross-sectional study by posting a questionnaire to 15,000 working-age persons, and 15.1% of all respondents (6121) reported that they very often experienced physical symptoms in the neck. The results showed that they also had many other symptoms very often, and 49% used a computer daily at work and 83.9% used cell phones. We compared physical/mental symptoms of persons with symptoms in the neck quite often or more, with others. We found significant differences in the physical/mental symptoms and use of cell phones and computers. The results suggest taking into account in the future that those persons' symptoms in the neck can be associated with use of cell phones or computers. We investigated the possible relation between neck symptoms and use of computers/cell phones. We found that persons, who very often had symptoms in the neck, had also other symptoms very often (e.g. exhaustion at work). Their use of information and communication technology (e.g. computers) can associate with their symptoms.

  1. The Relationship Between Cell Phone Use and Academic Performance in a Sample of U.S. College Students

    Directory of Open Access Journals (Sweden)

    Andrew Lepp

    2015-02-01

    Full Text Available The cell phone is ever-present on college campuses and is frequently used in settings where learning occurs. This study assessed the relationship between cell phone use and actual college grade point average (GPA after controlling for known predictors. As such, 536 undergraduate students from 82 self-reported majors at a large, public university were sampled. A hierarchical regression (R2 = .449 demonstrated that cell phone use was significantly (p < .001 and negatively (β = −.164 related to actual college GPA after controlling for demographic variables, self-efficacy for self-regulated learning, self-efficacy for academic achievement, and actual high school GPA, which were all significant predictors (p < .05. Thus, after controlling for other established predictors, increased cell phone use was associated with decreased academic performance. Although more research is needed to identify the underlying mechanisms, findings suggest a need to sensitize students and educators about the potential academic risks associated with high-frequency cell phone use.

  2. Mobile Phone on Campus

    Institute of Scientific and Technical Information of China (English)

    周成

    2005-01-01

    Communication revolution has brought a great convenience to modem society and people. Especially, the occurrence of mobile phone, in away, has changed the world where we live. Maybe the mobile phone was a luxury for only a decade ago. Now, it is no exaggeration4 to say that the difference between the parts and the present is as vast as that between earth and heaven. With no exception6, campus students also fall into the category called “cell-phone school”.

  3. Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis with focus on male reproductive system

    Directory of Open Access Journals (Sweden)

    Kesari Kavindra K

    2009-10-01

    Full Text Available Abstract Hazardous health effects stemming from exposure to radiofrequency electromagnetic waves (RF-EMW emitted from cell phones have been reported in the literature. However, the cellular target of RF-EMW is still controversial. This review identifies the plasma membrane as a target of RF-EMW. In addition, the effects of RF-EMW on plasma membrane structures (i.e. NADH oxidase, phosphatidylserine, ornithine decarboxylase and voltage-gated calcium channels are discussed. We explore the disturbance in reactive oxygen species (ROS metabolism caused by RF-EMW and delineate NADH oxidase mediated ROS formation as playing a central role in oxidative stress (OS due to cell phone radiation (with a focus on the male reproductive system. This review also addresses: 1 the controversial effects of RF-EMW on mammalian cells and sperm DNA as well as its effect on apoptosis, 2 epidemiological, in vivo animal and in vitro studies on the effect of RF-EMW on male reproductive system, and 3 finally, exposure assessment and dosimetry by computational biomodeling.

  4. Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis with focus on male reproductive system.

    Science.gov (United States)

    Desai, Nisarg R; Kesari, Kavindra K; Agarwal, Ashok

    2009-10-22

    Hazardous health effects stemming from exposure to radiofrequency electromagnetic waves (RF-EMW) emitted from cell phones have been reported in the literature. However, the cellular target of RF-EMW is still controversial. This review identifies the plasma membrane as a target of RF-EMW. In addition, the effects of RF-EMW on plasma membrane structures (i.e. NADH oxidase, phosphatidylserine, ornithine decarboxylase) and voltage-gated calcium channels are discussed. We explore the disturbance in reactive oxygen species (ROS) metabolism caused by RF-EMW and delineate NADH oxidase mediated ROS formation as playing a central role in oxidative stress (OS) due to cell phone radiation (with a focus on the male reproductive system). This review also addresses: 1) the controversial effects of RF-EMW on mammalian cells and sperm DNA as well as its effect on apoptosis, 2) epidemiological, in vivo animal and in vitro studies on the effect of RF-EMW on male reproductive system, and 3) finally, exposure assessment and dosimetry by computational biomodeling.

  5. A Cell Phone-Based Microphotometric System for Rapid Antimicrobial Susceptibility Testing.

    Science.gov (United States)

    Kadlec, Meichei Wang; You, David; Liao, Joseph C; Wong, Pak Kin

    2014-06-01

    This study demonstrates a low-cost, portable diagnostic system for rapid antimicrobial susceptibility testing in resource-limited settings. To determine the antimicrobial resistance phenotypically, the growth of pathogens in microwell arrays is detected under different antibiotic conditions. The use of a colorimetric cell viability reagent is shown to significantly improve the sensitivity of the assay compared with standard absorbance spectroscopy. Gas-permeable microwell arrays are incorporated for facilitating rapid bacterial growth and eliminating the requirement of bulky supporting equipment. Antibiotics can also be precoated in the microwell array to simplify the assay protocol toward point-of-care applications. Furthermore, a low-cost cell phone-based microphotometric system is developed for detecting the bacterial growth in the microwell array. By optimizing the operating conditions, the system allows antimicrobial susceptibility testing for samples with initial concentrations from 10(1) to 10(6) cfu/mL. Using urinary tract infection as the model system, we demonstrate rapid antimicrobial resistance profiling for uropathogens in both culture media and urine. With its simplicity and cost-effectiveness, the cell phone-based microphotometric system is anticipated to have broad applicability in resource-limited settings toward the management of infectious diseases caused by multidrug-resistant pathogens. © 2013 Society for Laboratory Automation and Screening.

  6. Quantitative Leaching of a Spent Cell Phone Printed Circuit Board by Hydrochloric acid

    Directory of Open Access Journals (Sweden)

    Alafara A. Baba

    2014-07-01

    Full Text Available This paper presents a kinetic data on the hydrometallurgical recovery of some metal ions from a printed circuit board (PCB of a spent cell phone by hydrochloric acid leaching. The effects of acid concentration, temperature and particle diameter on the dissolution efficiency at various leaching time intervals were examined. The results of the leaching investigations showed that the powdered cell phone dissolution increases with increasing acid concentration, system temperature with decreasing particle diameter at 360 rpm. With 2M HCl solution, about 88.49% of the sample was dissolved within 120 minutes using 0.075-0.112 mm particle diameter at 800 C. The results of the study indicated that the dissolution reaction could be represented by a shrinking core model with surface chemical reaction. A value of 0.61, 60.67 kJ/mol and 12.9s-1 were calculated as reaction order, activation energy and frequency factor, respectively for the dissolution process.

  7. Analysis of proteome response to the mobile phone radiation in two types of human primary endothelial cells

    Directory of Open Access Journals (Sweden)

    Kuster Niels

    2010-10-01

    Full Text Available Abstract Background Use of mobile phones has widely increased over the past decade. However, in spite of the extensive research, the question of potential health effects of the mobile phone radiation remains unanswered. We have earlier proposed, and applied, proteomics as a tool to study biological effects of the mobile phone radiation, using as a model human endothelial cell line EA.hy926. Exposure of EA.hy926 cells to 900 MHz GSM radiation has caused statistically significant changes in expression of numerous proteins. However, exposure of EA.hy926 cells to 1800 MHz GSM signal had only very small effect on cell proteome, as compared with 900 MHz GSM exposure. In the present study, using as model human primary endothelial cells, we have examined whether exposure to 1800 MHz GSM mobile phone radiation can affect cell proteome. Results Primary human umbilical vein endothelial cells and primary human brain microvascular endothelial cells were exposed for 1 hour to 1800 MHz GSM mobile phone radiation at an average specific absorption rate of 2.0 W/kg. The cells were harvested immediately after the exposure and the protein expression patterns of the sham-exposed and radiation-exposed cells were examined using two dimensional difference gel electrophoresis-based proteomics (2DE-DIGE. There were observed numerous differences between the proteomes of human umbilical vein endothelial cells and human brain microvascular endothelial cells (both sham-exposed. These differences are most likely representing physiological differences between endothelia in different vascular beds. However, the exposure of both types of primary endothelial cells to mobile phone radiation did not cause any statistically significant changes in protein expression. Conclusions Exposure of primary human endothelial cells to the mobile phone radiation, 1800 MHz GSM signal for 1 hour at an average specific absorption rate of 2.0 W/kg, does not affect protein expression, when the

  8. A global downregulation of microRNAs occurs in human quiescent satellite cells during myogenesis

    NARCIS (Netherlands)

    Koning, Merel; Werker, Paul M N; van Luyn, Marja J A; Krenning, Guido; Harmsen, Martin C

    2012-01-01

    During myogenesis, human satellite cells differentiate and form multinucleated myotubes, while a fraction of the human satellite cells enter quiescence. These quiescent satellite cells are able to activate, proliferate and contribute to muscle regeneration. Post-transcriptional regulation of

  9. Nanometer-scale sizing accuracy of particle suspensions on an unmodified cell phone using elastic light scattering.

    Directory of Open Access Journals (Sweden)

    Zachary J Smith

    Full Text Available We report on the construction of a Fourier plane imaging system attached to a cell phone. By illuminating particle suspensions with a collimated beam from an inexpensive diode laser, angularly resolved scattering patterns are imaged by the phone's camera. Analyzing these patterns with Mie theory results in predictions of size distributions of the particles in suspension. Despite using consumer grade electronics, we extracted size distributions of sphere suspensions with better than 20 nm accuracy in determining the mean size. We also show results from milk, yeast, and blood cells. Performing these measurements on a portable device presents opportunities for field-testing of food quality, process monitoring, and medical diagnosis.

  10. Post and during event effect of cell phone talking and texting on driving performance--a driving simulator study.

    Science.gov (United States)

    Thapa, Raju; Codjoe, Julius; Ishak, Sherif; McCarter, Kevin S

    2015-01-01

    A number of studies have been done in the field of driver distraction, specifically on the use of cell phone for either conversation or texting while driving. Researchers have focused on the driving performance of drivers when they were actually engaged in the task; that is, during the texting or phone conversation event. However, it is still unknown whether the impact of cell phone usages ceases immediately after the end of task. The primary objective of this article is to analyze the post-event effect of cell phone usage (texting and conversation) in order to verify whether the distracting effect lingers after the actual event has ceased. This study utilizes a driving simulator study of 36 participants to test whether a significant decrease in driver performance occurs during cell phone usage and after usage. Surrogate measures used to represent lateral and longitudinal control of the vehicle were standard deviation (SD) of lane position and mean velocity, respectively. RESULTS suggest that there was no significant decrease in driver performance (both lateral and longitudinal control) during and after the cell phone conversation. For the texting event, there were significant decreases in driver performance in both the longitudinal and lateral control of the vehicle during the actual texting task. The diminished longitudinal control ceased immediately after the texting event but the diminished lateral control lingered for an average of 3.38 s. The number of text messages exchanged did not affect the magnitude or duration of the diminished lateral control. The result indicates that the distraction and subsequent elevated crash risk of texting while driving linger even after the texting event has ceased. This finding has safety and policy implications in reducing distracted driving.

  11. Use of Advanced Solar Cells for Commercial Communication Satellites

    Science.gov (United States)

    Bailey, Sheila G.; Landis, Geoffrey A.

    1995-01-01

    The current generation of communications satellites are located primarily in geosynchronous Earth orbit (GEO). Over the next decade, however, a new generation of communications satellites will be built and launched, designed to provide a world-wide interconnection of portable telephones. For this mission, the satellites must be positioned in lower polar and near-polar orbits. To provide complete coverage, large numbers of satellites will be required. Because the required number of satellites decreases as the orbital altitude is increased, fewer satellites would be required if the orbit chosen were raised from low to intermediate orbit. However, in intermediate orbits, satellites encounter significant radiation due to trapped electrons and protons. Radiation tolerant solar cells may be necessary to make such satellites feasible. We analyze the amount of radiation encountered in low and intermediate polar orbits at altitudes of interest to next-generation communication satellites, calculate the expected degradation for silicon, GaAs, and InP solar cells, and show that the lifetimes can be significantly increased by use of advanced solar cells.

  12. The effects of electromagnetic waves emitted by the cell phones on the testicular tissue.

    Science.gov (United States)

    Karaman, Muhammet Ihsan; Gökçe, Ali Murat; Koca, Orhan; Karaman, Bilal; Öztürk, Metin Ishak; Yurdakul, Necati; Ercan, Feriha

    2014-12-30

    Various risks have emerged in parallel to the rapidly increasing use of cell phones. Herein we studied the effects of cell phone emitted electromagnetic waves (EMW) on rat testes. Twenty one adult male Albino rats were grouped into 3 groups each consisting of 7 rats. The first group was exposed to EMW on talk mode for 8 hours per day for 20 days and then their testes were extracted. The testes of the second group were extracted after 20 days of whole day EMW exposure. The third group was the control group. For the statistical analysis Mann- Whitney U analysis was performed. At light microscopic examination of the testicular tissue, the existence of a high number of immature cells in the lumen of the seminiferous tubule in addition to the normal seminiferous tubules, besides irregular tubules with a reduction in the spermatogenic cell lines and tubules without lumen were observed in groups 1 and 2. Histopathological alterations were scored as 0 = none, 1 = low, 2 = medium, 3 = serious. The average scores of the three groups were found to be 4.25 ± 1.5 for the group 1, 4.33 ± 3.9 for the group 2 and 0.37 ± 1.1 for the group 3 respectively. As a result of the statistical evaluation, group 1 and group 2 had significantly higher scores than the control group (p = 0.001). Infertility is one of the current problems of today due to a rapid increase in its incidence and cost. The negative effects of the EMWs on the testis should be taken into account and the necessary measures should be taken for prevention.

  13. The effects of electromagnetic waves emitted by the cell phones on the testicular tissue

    Directory of Open Access Journals (Sweden)

    Muhammet Ihsan Karaman

    2014-12-01

    Full Text Available Objectives: Various risks have emerged in parallel to the rapidly increasing use of cell phones. Herein we studied the effects of cell phone emitted electromagnetic waves (EMW on rat testes. Material and Methods: Twenty one adult male Albino rats were grouped into 3 groups each consisting of 7 rats. The first group was exposed to EMW on talk mode for 8 hours per day for 20 days and then their testes were extracted. The testes of the second group were extracted after 20 days of whole day EMW exposure. The third group was the control group. For the statistical analysis Mann- Whitney U analysis was performed. Results: At light microscopic examination of the testicular tissue, the existence of a high number of immature cells in the lumen of the seminiferous tubule in addition to the normal seminiferous tubules, besides irregular tubules with a reduction in the spermatogenic cell lines and tubules without lumen were observed in groups 1 and 2. Histopathological alterations were scored as 0 = none, 1 = low, 2 = medium, 3 = serious. The average scores of the three groups were found to be 4.25 ± 1.5 for the group 1, 4.33 ± 3.9 for the group 2 and 0.37 ± 1.1 for the group 3 respectively. As a result of the statistical evaluation, group 1 and group 2 had significantly higher scores than the control group (p = 0.001. Conclusion: Infertility is one of the current problems of today due to a rapid increase in its incidence and cost. The negative effects of the EMWs on the testis should be taken into account and the necessary measures should be taken for prevention.

  14. Exposure to cell phone radiation up-regulates apoptosis genes in primary cultures of neurons and astrocytes.

    Science.gov (United States)

    Zhao, Tian-Yong; Zou, Shi-Ping; Knapp, Pamela E

    2007-01-22

    The health effects of cell phone radiation exposure are a growing public concern. This study investigated whether expression of genes related to cell death pathways are dysregulated in primary cultured neurons and astrocytes by exposure to a working Global System for Mobile Communication (GSM) cell phone rated at a frequency of 1900MHz. Primary cultures were exposed to cell phone emissions for 2h. We used array analysis and real-time RT-PCR to show up-regulation of caspase-2, caspase-6 and Asc (apoptosis associated speck-like protein containing a card) gene expression in neurons and astrocytes. Up-regulation occurred in both "on" and "stand-by" modes in neurons, but only in "on" mode in astrocytes. Additionally, astrocytes showed up-regulation of the Bax gene. The effects are specific since up-regulation was not seen for other genes associated with apoptosis, such as caspase-9 in either neurons or astrocytes, or Bax in neurons. The results show that even relatively short-term exposure to cell phone radiofrequency emissions can up-regulate elements of apoptotic pathways in cells derived from the brain, and that neurons appear to be more sensitive to this effect than astrocytes.

  15. Effective fiber hypertrophy in satellite cell-depleted skeletal muscle.

    Science.gov (United States)

    McCarthy, John J; Mula, Jyothi; Miyazaki, Mitsunori; Erfani, Rod; Garrison, Kelcye; Farooqui, Amreen B; Srikuea, Ratchakrit; Lawson, Benjamin A; Grimes, Barry; Keller, Charles; Van Zant, Gary; Campbell, Kenneth S; Esser, Karyn A; Dupont-Versteegden, Esther E; Peterson, Charlotte A

    2011-09-01

    An important unresolved question in skeletal muscle plasticity is whether satellite cells are necessary for muscle fiber hypertrophy. To address this issue, a novel mouse strain (Pax7-DTA) was created which enabled the conditional ablation of >90% of satellite cells in mature skeletal muscle following tamoxifen administration. To test the hypothesis that satellite cells are necessary for skeletal muscle hypertrophy, the plantaris muscle of adult Pax7-DTA mice was subjected to mechanical overload by surgical removal of the synergist muscle. Following two weeks of overload, satellite cell-depleted muscle showed the same increases in muscle mass (approximately twofold) and fiber cross-sectional area with hypertrophy as observed in the vehicle-treated group. The typical increase in myonuclei with hypertrophy was absent in satellite cell-depleted fibers, resulting in expansion of the myonuclear domain. Consistent with lack of nuclear addition to enlarged fibers, long-term BrdU labeling showed a significant reduction in the number of BrdU-positive myonuclei in satellite cell-depleted muscle compared with vehicle-treated muscle. Single fiber functional analyses showed no difference in specific force, Ca(2+) sensitivity, rate of cross-bridge cycling and cooperativity between hypertrophied fibers from vehicle and tamoxifen-treated groups. Although a small component of the hypertrophic response, both fiber hyperplasia and regeneration were significantly blunted following satellite cell depletion, indicating a distinct requirement for satellite cells during these processes. These results provide convincing evidence that skeletal muscle fibers are capable of mounting a robust hypertrophic response to mechanical overload that is not dependent on satellite cells.

  16. Effective fiber hypertrophy in satellite cell-depleted skeletal muscle

    Science.gov (United States)

    McCarthy, John J.; Mula, Jyothi; Miyazaki, Mitsunori; Erfani, Rod; Garrison, Kelcye; Farooqui, Amreen B.; Srikuea, Ratchakrit; Lawson, Benjamin A.; Grimes, Barry; Keller, Charles; Van Zant, Gary; Campbell, Kenneth S.; Esser, Karyn A.; Dupont-Versteegden, Esther E.; Peterson, Charlotte A.

    2011-01-01

    An important unresolved question in skeletal muscle plasticity is whether satellite cells are necessary for muscle fiber hypertrophy. To address this issue, a novel mouse strain (Pax7-DTA) was created which enabled the conditional ablation of >90% of satellite cells in mature skeletal muscle following tamoxifen administration. To test the hypothesis that satellite cells are necessary for skeletal muscle hypertrophy, the plantaris muscle of adult Pax7-DTA mice was subjected to mechanical overload by surgical removal of the synergist muscle. Following two weeks of overload, satellite cell-depleted muscle showed the same increases in muscle mass (approximately twofold) and fiber cross-sectional area with hypertrophy as observed in the vehicle-treated group. The typical increase in myonuclei with hypertrophy was absent in satellite cell-depleted fibers, resulting in expansion of the myonuclear domain. Consistent with lack of nuclear addition to enlarged fibers, long-term BrdU labeling showed a significant reduction in the number of BrdU-positive myonuclei in satellite cell-depleted muscle compared with vehicle-treated muscle. Single fiber functional analyses showed no difference in specific force, Ca2+ sensitivity, rate of cross-bridge cycling and cooperativity between hypertrophied fibers from vehicle and tamoxifen-treated groups. Although a small component of the hypertrophic response, both fiber hyperplasia and regeneration were significantly blunted following satellite cell depletion, indicating a distinct requirement for satellite cells during these processes. These results provide convincing evidence that skeletal muscle fibers are capable of mounting a robust hypertrophic response to mechanical overload that is not dependent on satellite cells. PMID:21828094

  17. M-cadherin-mediated intercellular interactions activate satellite cell division.

    Science.gov (United States)

    Marti, Merce; Montserrat, Núria; Pardo, Cristina; Mulero, Lola; Miquel-Serra, Laia; Rodrigues, Alexandre Miguel Cavaco; Andrés Vaquero, José; Kuebler, Bernd; Morera, Cristina; Barrero, María José; Izpisua Belmonte, Juan Carlos

    2013-11-15

    Adult muscle stem cells and their committed myogenic precursors, commonly referred to as the satellite cell population, are involved in both muscle growth after birth and regeneration after damage. It has been previously proposed that, under these circumstances, satellite cells first become activated, divide and differentiate, and only later fuse to the existing myofiber through M-cadherin-mediated intercellular interactions. Our data show that satellite cells fuse with the myofiber concomitantly to cell division, and only when the nuclei of the daughter cells are inside the myofiber, do they complete the process of differentiation. Here we demonstrate that M-cadherin plays an important role in cell-to-cell recognition and fusion, and is crucial for cell division activation. Treatment of satellite cells with M-cadherin in vitro stimulates cell division, whereas addition of anti-M-cadherin antibodies reduces the cell division rate. Our results suggest an alternative model for the contribution of satellite cells to muscle development, which might be useful in understanding muscle regeneration, as well as muscle-related dystrophies.

  18. Effect of Ultrahigh Frequency Radiation Emitted from 2G Cell Phone on Developing Lens of Chick Embryo: A Histological Study

    Directory of Open Access Journals (Sweden)

    Mary Hydrina D'Silva

    2014-01-01

    Full Text Available A Mobile phone in operation emits a pulsed radiofrequency electromagnetic field which is absorbed into the user’s body particularly the head region. Contradictory scientific reports on the health effect of nonionizing radiations on biological tissues have prompted to undertake the present study to evaluate the damage in the developing lens of a chick embryo following exposure to radiation emitted from a 2G cell phone. Fertilized chick embryos were incubated in two groups in a standard egg incubator. The experiment group was exposed to radiation emitted from a 2G cell phone. On completion of scheduled duration, the embryos were collected and processed for routine histological studies. The 9th to 12th day chick embryo eyes were processed for assessment of DNA damage using the alkaline comet assay technique. The lens thickness and the equatorial diameter were measured using oculometer and statistically compared for both groups. In the present study, the exposure of chick embryos to a 2G cell phone caused structural changes in lens epithelial cells, formation of cystic cells and spaces, distortion of lens fibers, and formation of posterior aberrant nuclear layer. The DNA damage in the developing eyes of the experiment group assessed by comet assay was highly significant.

  19. The Effects of Cell Phone Waves (900 MHz-GSM Band on Sperm Parameters and Total Antioxidant Capacity in Rats

    Directory of Open Access Journals (Sweden)

    Masoud Ghanbari

    2013-01-01

    Full Text Available Background: There is tremendous concern regarding the possible adverse effects of cellphone microwaves. Contradictory results, however, have been reported for the effectsof these waves on the body. In the present study, the effect of cell phone microwaves onsperm parameters and total antioxidant capacity was investigated with regard to the durationof exposure and the frequency of these waves.Materials and Methods: This experimental study was performed on 28 adult male Wistarrats (200-250 g. The animals were randomly assigned to four groups (n=7: i. control; ii.two-week exposure to cell phone-simulated waves; iii. three-week exposure to cell phonesimulatedwaves; and iv. two-week exposure to cell phone antenna waves. In all groups,sperm analysis was performed based on standard methods and we determined the meansperm total antioxidant capacity according to the ferric reducing ability of plasma (FRAPmethod. Data were analyzed by one-way ANOVA followed by Tukey’s test using SPSSversion 16 software.Results: The results indicated that sperm viability, motility, and total antioxidant capacityin all exposure groups decreased significantly compared to the control group (p<0.05.Increasing the duration of exposure from 2 to 3 weeks caused a statistically significantdecrease in sperm viability and motility (p<0.05.Conclusion: Exposure to cell phone waves can decrease sperm viability and motility inrats. These waves can also decrease sperm total antioxidant capacity in rats and result inoxidative stress.

  20. Is health literacy related to health behaviors and cell phone usage patterns among the text4baby target population?

    Science.gov (United States)

    Poorman, Elisabeth; Gazmararian, Julie; Elon, Lisa; Parker, Ruth

    2014-01-01

    Text4baby provides educational text messages to pregnant and postpartum women and targets underserved women. The primary purpose of this study is to examine the health behaviors and cell phone usage patterns of a text4baby target population and the associations with health literacy. Pregnant and postpartum women were recruited from two Women, Infant and Children clinics in Atlanta. Women were asked about their demographics, selected pregnancy or postpartum health behaviors, and cell phone usage patterns. Health literacy skills were measured with the English version of the Newest Vital Sign. Multivariable logistic regression was used to examine health behaviors and cell usage patterns by health literacy classification, controlling for commonly accepted confounders. Four hundred sixty-eight women were recruited, and 445 completed the Newest Vital Sign. Of these, 22% had inadequate health literacy, 50% had intermediate health literacy, and 28% had adequate health literacy skills. Compared to adequate health literacy, limited literacy was independently associated with not taking a daily vitamin during pregnancy (OR 3.6, 95% CI: 1.6, 8.5) and never breastfeeding their infant (OR 1.4, 95% CI: 1.1, 1.8). The majority (69.4%) of respondents received nine or more text messages a day prior to enrollment, one in four participants (24.6%) had changed their number within the last six months, and 7.0% of study participants shared a cell phone. Controlling for potentially confounding factors, those with limited health literacy were more likely to share a cell phone than those with adequate health literacy (OR 2.57, 95% CI: 1.79, 3.69). Text4baby messages should be appropriate for low health literacy levels, especially as this population may have higher prevalence of targeted unhealthy behaviors. Text4baby and other mhealth programs targetting low health literacy populations should also be aware of the different ways that these populations use their cell phones, including: sharing

  1. The feasibility of cell phone based electronic diaries for STI/HIV research

    Directory of Open Access Journals (Sweden)

    Hensel Devon J

    2012-06-01

    Full Text Available Abstract Background Self-reports of sensitive, socially stigmatized or illegal behavior are common in STI/HIV research, but can raise challenges in terms of data reliability and validity. The use of electronic data collection tools, including ecological momentary assessment (EMA, can increase the accuracy of this information by allowing a participant to self-administer a survey or diary entry, in their own environment, as close to the occurrence of the behavior as possible. In this paper, we evaluate the feasibility of using cell phone-based EMA as a tool for understanding sexual risk and STI among adult men and women. Methods As part of a larger prospective clinical study on sexual risk behavior and incident STI in clinically recruited adult men and women, using study-provided cell phones, participants (N = 243 completed thrice–daily EMA diaries monitoring individual and partner-specific emotional attributes, non-sexual activities, non-coital or coital sexual behaviors, and contraceptive behaviors. Using these data, we assess feasibility in terms of participant compliance, behavior reactivity, general method acceptability and method efficacy for capturing behaviors. Results Participants were highly compliant with diary entry protocol and schedule: over the entire 12 study weeks, participants submitted 89.7% (54,914/61,236 of the expected diary entries, with an average of 18.86 of the 21 expected diaries (85.7% each week. Submission did not differ substantially across gender, race/ethnicity and baseline sexually transmitted infection status. A sufficient volume and range of sexual behaviors were captured, with reporting trends in different legal and illegal behaviors showing small variation over time. Participants found the methodology to be acceptable, enjoyed and felt comfortable participating in the study. Conclusion Achieving the correct medium of data collection can drastically improve, or degrade, the timeliness and quality of an

  2. Compliance to Cell Phone-Based EMA Among Latino Youth in Outpatient Treatment.

    Science.gov (United States)

    Comulada, W Scott; Lightfoot, Marguerita; Swendeman, Dallas; Grella, Christine; Wu, Nancy

    2015-01-01

    Outpatient treatment practices for adolescent substance users utilize retrospective self-report to monitor drug use. Cell phone-based ecological momentary assessment (CEMA) overcomes retrospective self-report biases and can enhance outpatient treatment, particularly among Latino adolescents, who have been understudied with regard to CEMA. This study explores compliance to text message-based CEMA with youth (n = 28; 93% Latino) in outpatient treatment. Participants were rotated through daily, random, and event-based CEMA strategies for 1-month periods. Overall compliance was high (>80%). Compliance decreased slightly over the study period and was less during random versus daily strategies and on days when alcohol use was retrospectively reported. Findings suggest that CEMA is a viable monitoring tool for Latino youth in outpatient treatment, but further study is needed to determine optimal CEMA strategies, monitoring time periods, and the appropriateness of CEMA for differing levels of substance use.

  3. AWireless Local Area Network Soft Cell Phone (SCP System with Multimedia and Data Services

    Directory of Open Access Journals (Sweden)

    Olakanmi O.Oladayo

    2014-01-01

    Full Text Available Most organizations concurrently maintain private Automatic Branch Exchange (PABX and Local Area Network (LAN for information interchange within their organization. This is obviously a waste of resources and avoidable duplication of communication systems. The existing LAN can be used as a communication backbone for the in house telephone operations with no extra cost and resources. In view of this, a portable and a platform independent Software-Based Cell Phone (SCP was proposed for the existing LANs infrastructure in the organizations. The SPC is a telephony application with a user friendly interface which is capable of handling voice, video and text messages without compromising the Quality of Service (QoS of the existing LAN.

  4. Comparing Cell Phone-Based and Traditional Lecture-Based Teaching Methods' Effects on Agricultural Students' Learning

    Directory of Open Access Journals (Sweden)

    Abdolhamid Papzan

    2010-10-01

    Full Text Available Regarding the increased speed of creating new knowledge and the development of communication technologies, like cell phone, which makes it possible the access to various unlimited resources and data in an unlimited time and place, and regarding many positive aspects of applying it in schools and the necessity of adjusting with changes and the correct use of this new technology, the present research was conducted to examine the effect of teaching via cell phone on students learning in Khooshehaye Zarin agricultural school in Rawansar, Kermanshah province, and comparing it with traditional lecture method. In a semi-experimental research method, 30 male students were selected through random sampling method as the research sample, divided into two paired groups, 15 for experimental group and 15 for control group, based on age, educational status, previous grade point average and family economical status. Data collection tool was a 10 item test based on behavioral objectives. The experimental group was taught in two sessions of two hours through cell phone, and the control group was taught the same topic through traditional lecture method in exactly the same amount of time. Post–test was performed on two groups through the above-mentioned 10 item test and the results were analyzed through t test method. The results showed that teaching via cell phone has more effects on students learning compared with traditional lecture method.

  5. Let Them Have Their Cell Phone (And Let Them Read to It Too): Technology, Writing Instruction and Textual Obsolescence

    Science.gov (United States)

    Shahar, Jed

    2012-01-01

    Cell phone ubiquity enables students to record and share audio file versions of their essays for proofreading purposes. Adopting this practice in community college developmental writing classes leads to an investigation of both writing as a technology and the influence of modern technology on composition and composition pedagogy.

  6. Prospect for Cell Phones as Instructional Tools in the EFL Classroom: A Case Study of Jahangirnagar University, Bangladesh

    Science.gov (United States)

    Begum, Roksana

    2011-01-01

    The aim of this study was to investigate the potentiality of cell phone use in the EFL classroom of Bangladesh as an instructional tool. The researcher conducted a case study on Jahangirnagar University of Bangladesh. For the study, some SMS based class tests were conducted in the English Department of the university where one hundred…

  7. Cell phone internet access, online sexual solicitation, partner seeking, and sexual risk behavior among adolescents.

    Science.gov (United States)

    Rice, Eric; Winetrobe, Hailey; Holloway, Ian W; Montoya, Jorge; Plant, Aaron; Kordic, Timothy

    2015-04-01

    Online partner seeking is associated with sexual risk behavior among young adults (specifically men who have sex with men), but this association has yet to be explored among a probability sample of adolescents. Moreover, cell phone internet access and sexual risk taking online and offline have not been explored. A probability sample (N = 1,831) of Los Angeles Unified School District high school students was collected in 2011. Logistic regression models assessed relationships between specific sexual risk behaviors (online sexual solicitation, seeking partners online, sex with internet-met partners, condom use) and frequency of internet use, internet access points, and demographics. Students with cell phone internet access were more likely to report being solicited online for sex, being sexually active, and having sex with an internet-met partner. Bisexual-identifying students reported higher rates of being approached online for sex, being sexually active, and not using condoms at last sex. Gay, lesbian, and questioning (GLQ) students were more likely to report online partner seeking and unprotected sex at last sex with an internet-met partner. Additionally, having sex with an internet-met partner was associated with being male, online sexual solicitation, and online partner seeking. Internet- and school-based sexual health programs should incorporate safety messages regarding online sexual solicitation, seeking sex partners online, and engaging in safer sex practices with all partners. Programs must target adolescents of all sexual identities, as adolescents may not yet be "out," and bisexual and GLQ adolescents are more likely to engage in risky sex behaviors.

  8. Feasibility study of a mini fuel cell to detect interference from a cellular phone

    Science.gov (United States)

    Abdullah, M. O.; Gan, Y. K.

    Fuel cells produce electricity without involving combustion processes. They generate no noise, vibration or air pollution and are therefore suitable for use in many vibration-free power-generating applications. In this study, a mini alkaline fuel cell signal detector system has been designed, constructed and tested. The initial results have shown the applicability of such system for used as an indicator of signal disturbance from cellular phones. A small disturbance even at 4 mV cm -1, corresponding to an amplitude of 12-18 mG in terms of electromagnetic field, can be well detected by such a device. Subsequently, a thermodynamics model has been developed to provide a parametric study by simulation to show the likely performance of the fuel cell alone in other environments. As such the model can provide many useful generic design data for alkaline fuel cells. Two general conclusions can be drawn from the present theoretical study: (i) fuel cell performance increases with temperature, pressure and correction factor, C f; (ii) the temperature factor (E/ T) increases with increasing temperature and with increasing pressure factor.

  9. Muscle Satellite Cells: Exploring the Basic Biology to Rule Them.

    Science.gov (United States)

    Almeida, Camila F; Fernandes, Stephanie A; Ribeiro Junior, Antonio F; Keith Okamoto, Oswaldo; Vainzof, Mariz

    2016-01-01

    Adult skeletal muscle is a postmitotic tissue with an enormous capacity to regenerate upon injury. This is accomplished by resident stem cells, named satellite cells, which were identified more than 50 years ago. Since their discovery, many researchers have been concentrating efforts to answer questions about their origin and role in muscle development, the way they contribute to muscle regeneration, and their potential to cell-based therapies. Satellite cells are maintained in a quiescent state and upon requirement are activated, proliferating, and fusing with other cells to form or repair myofibers. In addition, they are able to self-renew and replenish the stem pool. Every phase of satellite cell activity is highly regulated and orchestrated by many molecules and signaling pathways; the elucidation of players and mechanisms involved in satellite cell biology is of extreme importance, being the first step to expose the crucial points that could be modulated to extract the optimal response from these cells in therapeutic strategies. Here, we review the basic aspects about satellite cells biology and briefly discuss recent findings about therapeutic attempts, trying to raise questions about how basic biology could provide a solid scaffold to more successful use of these cells in clinics.

  10. Human Satellite Cell Transplantation and Regeneration from Diverse Skeletal Muscles

    Directory of Open Access Journals (Sweden)

    Xiaoti Xu

    2015-09-01

    Full Text Available Identification of human satellite cells that fulfill muscle stem cell criteria is an unmet need in regenerative medicine. This hurdle limits understanding how closely muscle stem cell properties are conserved among mice and humans and hampers translational efforts in muscle regeneration. Here, we report that PAX7 satellite cells exist at a consistent frequency of 2–4 cells/mm of fiber in muscles of the human trunk, limbs, and head. Xenotransplantation into mice of 50–70 fiber-associated, or 1,000–5,000 FACS-enriched CD56+/CD29+ human satellite cells led to stable engraftment and formation of human-derived myofibers. Human cells with characteristic PAX7, CD56, and CD29 expression patterns populated the satellite cell niche beneath the basal lamina on the periphery of regenerated fibers. After additional injury, transplanted satellite cells robustly regenerated to form hundreds of human-derived fibers. Together, these findings conclusively delineate a source of bona-fide endogenous human muscle stem cells that will aid development of clinical applications.

  11. SPATIAL AND TEMPORAL ANALYSIS OF HUMAN MOVEMENTS AND APPLICATIONS FOR DISASTER RESPONSE MANAGEMENT UTILIZING CELL PHONE USAGE DATA

    Directory of Open Access Journals (Sweden)

    M. Yasumiishi

    2015-07-01

    Full Text Available As cell phone usage becomes a norm in our daily lives, analysis and application of the data has become part of various research fields. This study focuses on the application of cell phone usage data to disaster response management. Cell phones work as a communication link between emergency responders and victims during and after a major disaster. This study recognizes that there are two kinds of disasters, one with an advance warning, and one without an advance warning. Different movement distance between a day with a blizzard (advanced warning and a normal weather day was identified. In the scenario of a day with an extreme event without advanced warning (earthquake, factors that alter the phone users' movements were analyzed. Lastly, combining both cases, a conceptual model of human movement factors is proposed. Human movements consist of four factors that are push factors, movement-altering factors, derived attributes and constraint factors. Considering each category of factors in case of emergency, it should be necessary that we prepare different kinds of emergency response plans depending on the characteristics of a disaster.

  12. Lifestyle intervention using an internet-based curriculum with cell phone reminders for obese Chinese teens: a randomized controlled study.

    Directory of Open Access Journals (Sweden)

    Anisha A Abraham

    Full Text Available Obesity is an increasing public health problem affecting young people. The causes of obesity are multi-factorial among Chinese youth including lack of physical activity and poor eating habits. The use of an internet curriculum and cell phone reminders and texting may be an innovative means of increasing follow up and compliance with obese teens. The objectives of this study were to determine the feasibility of using an adapted internet curriculum and existing nutritional program along with cell phone follow up for obese Chinese teens.This was a randomized controlled study involving obese teens receiving care at a paediatric obesity clinic of a tertiary care hospital in Hong Kong. Forty-eight subjects aged 12 to 18 years were randomized into three groups. The control group received usual care visits with a physician in the obesity clinic every three months. The first intervention (IT group received usual care visits every three months plus a 12-week internet-based curriculum with cell phone calls/texts reminders. The second intervention group received usual care visits every three months plus four nutritional counselling sessions.The use of the internet-based curriculum was shown to be feasible as evidenced by the high recruitment rate, internet log-in rate, compliance with completing the curriculum and responses to phone reminders. No significant differences in weight were found between IT, sLMP and control groups.An internet-based curriculum with cell phone reminders as a supplement to usual care of obesity is feasible. Further study is required to determine whether an internet plus text intervention can be both an effective and a cost-effective adjunct to changing weight in obese youth.Chinese Clinical Trial Registry ChiCTR-TRC-12002624.

  13. [Molecular mechanism maintaining muscle satellite cells and the roles in sarcopenia.

    Science.gov (United States)

    Takemoto, Yusei; Fukada, So-Ichiro

    2017-01-01

    Skeletal muscle has its stem cell named satellite cell. The absence of satellite cells does not allow muscle regeneration, it is unquestionable that satellite cell is indispensable for muscle regeneration processes. A certain number of satellite cells appear to be necessary for the successful muscle regeneration, meaning the maintenance of the satellite cells is essential for the functional homeostasis of skeletal muscle. Recent studies have revealed the molecular mechanism underlying satellite cell maintenance in a steady state. A loss of those molecules responsible for the maintenance often results in decreased satellite cell pool and reduced regeneration ability. On the other hand, the contribution of satellite cells to muscle hypertrophy or aged-related atrophy(sarcopenia)is controversial. In this review, we will introduce the molecules that regulate satellite cells homeostasis in the dormant state and then further discuss the recent results on the roles of satellite cell in sarcopenia.

  14. In Vitro Effect of Cell Phone Radiation on Motility, DNA Fragmentation and Clusterin Gene Expression in Human Sperm

    Directory of Open Access Journals (Sweden)

    Adel Zalata

    2015-04-01

    Full Text Available Background: Use of cellular phones emitting radiofrequency electromagnetic field (RF-EMF has been increased exponentially and become a part of everyday life. This study aimed to investigate the effects of in vitro RF-EMF exposure emitted from cellular phones on sperm motility index, sperm DNA fragmentation and seminal clusterin (CLU gene expression. Materials and Methods: In this prospective study, a total of 124 semen samples were grouped into the following main categories: i. normozoospermia (N, n=26, ii. asthenozoospermia (A, n=32, iii. asthenoteratozoospermia (AT, n=31 and iv. oligoasthenoteratozoospermia (OAT, n=35. The same semen samples were then divided into two portions non-exposed and exposed samples to cell phone radiation for 1 hour. Before and immediately after exposure, both aliquots were subjected to different assessments for sperm motility, acrosin activity, sperm DNA fragmentation and CLU gene expression. Statistical differences were analyzed using paired t student test for comparisons between two sub-groups where pAT>A>N groups, respectively (p<0.05. Conclusion: Cell phone emissions have a negative impact on exposed sperm motility index, sperm acrosin activity, sperm DNA fragmentation and seminal CLU gene expression, especially in OAT cases.

  15. The use of cell phone and insight into its potential human health impacts.

    Science.gov (United States)

    Kim, Ki-Hyun; Kabir, Ehsanul; Jahan, Shamin Ara

    2016-04-01

    The rapid evolution of mobile phone technology has raised public concern about its possible association with adverse health effects. Given the huge number of mobile phone users at present days, even simple adverse health effects could have major implications. This article reviews the present knowledge concerning the health effects stemming from the use of cellular phones by emphasizing adverse biological effects, epidemiological issues, and indirect health effects. A line of epidemiological evidence suggests that there is no concrete association between mobile phone radiation and cancer. The evidence regarding the occurrence of cancer due to exposure to the radio frequency energy of mobile phones is nonetheless conflicting. Consequently, long-term research in this field is necessary to account for the vital issue of this scientific research to the public in a meaningful way.

  16. Providing cell phone numbers and e-mail addresses to patients: The patient’s perspective, a cross sectional study

    Directory of Open Access Journals (Sweden)

    Peleg Roni

    2012-08-01

    Full Text Available Abstract Background Today patients can consult with their treating physician by cell phone or e-mail. These means of communication enhance the quality of medical care and increase patient satisfaction, but they can also impinge on physicians’ free time and their patient schedule while at work. The objective of this study is to assess the attitudes and practice of patients on obtaining the cell phone number or e-mail address of their physician for the purpose of medical consultation. Methods Personal interviews with patients, 18 years of age or above, selected by random sampling from the roster of adults insured by Clalit Health Services, Southern Division. The total response rate was 41%. The questionnaire included questions on the attitude and practice of patients towards obtaining their physician’s cell phone number or e-mail address. Comparisons were performed using Chi-square tests to analyze statistically significant differences of categorical variables. Two-tailed p values less than 0.05 were considered statistically significant, with a power of 0.8. Results The study sample included 200 patients with a mean age of 46.6 ± 17.1, of whom 110 were women (55%. Ninety-three (46.5% responded that they would be very interested in obtaining their physician’s cell phone number, and an additional 83 (41.5% would not object to obtaining it. Of the 171 patients (85.5% who had e-mail addresses, 25 (14.6% said they would be very interested in obtaining their physician’s e-mail address, 85 (49.7% said they would not object to getting it, and 61 (35.7% were not interested. In practice only one patient had requested the physician’s e-mail address and none actually had it. Conclusions Patients favored cell phones over e-mail for consulting with their treating physicians. With new technologies such as cell phones and e-mail in common use, it is important to determine how they can be best used and how they should be integrated into the flow

  17. The impact of cell phone use on the intensity and liking of a bout of treadmill exercise.

    Directory of Open Access Journals (Sweden)

    Michael J Rebold

    Full Text Available This study used a within-subjects design to assess the effect of three common cellular telephone (cell phone functions (texting, talking, listening to music on planned exercise. Forty-four young adults (n = 33 females, 21.8 ± 1.3 years each participated in four, separate, 30-minute exercise conditions on a treadmill in a random order. During each condition, the treadmill speed display was covered and grade was fixed at zero. However, participants were able to alter treadmill speed as desired. Throughout the texting and talking conditions, research personnel used a pre-determined script to simulate cell phone conversations. During the music condition, participants used their cell phone to listen to music of their choice. Finally, participants completed a control condition with no cell phone access. For each condition, average treadmill speed, heart rate and liking (via visual analog scale were assessed. Treadmill speed (3.4 ± 1.3 miles∙hour(-1, heart rate (122.3 ± 24.3 beats∙min(-1 and liking (7.5 ± 1.5 cm in the music condition were significantly (p ≤ 0.014 greater than all other conditions. Treadmill speed in the control condition (3.1 ± 1.2 miles∙hour(-1 was significantly (p = 0.04 greater than both texting and talking (2.8 ± 1.1 miles∙hour(-1 each. Heart rate during the control condition (115.4 ± 22.8 beats∙min(-1 was significantly (p = 0.04 greater than texting (109.9 ± 16.4 beats∙min(-1 but not talking (112.6 ± 16.1 beats∙min(-1. Finally, liking during the talking condition (5.4 ± 2.2 cm was greater (p = 0.05 than the control (4.3 ± 2.2 cm but not the texting (5.1 ± 2.2 cm conditions. In conclusion, using a cell phone for listening to music can increase the intensity (speed and heart rate and liking of a bout of treadmill exercise. However, other common cell phone uses (texting and talking can interfere with treadmill exercise and reduce intensity.

  18. Reaching rural women: breast cancer prevention information seeking behaviors and interest in Internet, cell phone, and text use.

    Science.gov (United States)

    Kratzke, Cynthia; Wilson, Susan; Vilchis, Hugo

    2013-02-01

    The purpose of this study was to examine the breast cancer prevention information seeking behaviors among rural women, the prevalence of Internet, cell, and text use, and interest to receive breast cancer prevention information cell and text messages. While growing literature for breast cancer information sources supports the use of the Internet, little is known about breast cancer prevention information seeking behaviors among rural women and mobile technology. Using a cross-sectional study design, data were collected using a survey. McGuire's Input-Ouput Model was used as the framework. Self-reported data were obtained from a convenience sample of 157 women with a mean age of 60 (SD = 12.12) at a rural New Mexico imaging center. Common interpersonal information sources were doctors, nurses, and friends and common channel information sources were television, magazines, and Internet. Overall, 87% used cell phones, 20% had an interest to receive cell phone breast cancer prevention messages, 47% used text messaging, 36% had an interest to receive text breast cancer prevention messages, and 37% had an interest to receive mammogram reminder text messages. Bivariate analysis revealed significant differences between age, income, and race/ethnicity and use of cell phones or text messaging. There were no differences between age and receiving text messages or text mammogram reminders. Assessment of health information seeking behaviors is important for community health educators to target populations for program development. Future research may identify additional socio-cultural differences.

  19. Mobile Phone

    Institute of Scientific and Technical Information of China (English)

    籍万杰

    2004-01-01

    Your mobile phone rings.and instead of usual electronic signals,it's playing your favorite music.A friend sends your favorite song to cheer you up.One day,a record company might forward new records and music videos to your phone.

  20. Optimization of injection molding process parameters for a plastic cell phone housing component

    Science.gov (United States)

    Rajalingam, Sokkalingam; Vasant, Pandian; Khe, Cheng Seong; Merican, Zulkifli; Oo, Zeya

    2016-11-01

    To produce thin-walled plastic items, injection molding process is one of the most widely used application tools. However, to set optimal process parameters is difficult as it may cause to produce faulty items on injected mold like shrinkage. This study aims at to determine such an optimum injection molding process parameters which can reduce the fault of shrinkage on a plastic cell phone cover items. Currently used setting of machines process produced shrinkage and mis-specified length and with dimensions below the limit. Thus, for identification of optimum process parameters, maintaining closer targeted length and width setting magnitudes with minimal variations, more experiments are needed. The mold temperature, injection pressure and screw rotation speed are used as process parameters in this research. For optimal molding process parameters the Response Surface Methods (RSM) is applied. The major contributing factors influencing the responses were identified from analysis of variance (ANOVA) technique. Through verification runs it was found that the shrinkage defect can be minimized with the optimal setting found by RSM.

  1. How connected are people with schizophrenia? Cell phone, computer, email, and social media use.

    Science.gov (United States)

    Miller, Brian J; Stewart, Adriana; Schrimsher, John; Peeples, Dale; Buckley, Peter F

    2015-02-28

    Technologies such as Internet based social media network (SMN) websites are becoming an important part of many adult lives; however, less is known about their use in patients with schizophrenia. We need to determine (1) how "connected" are patients with schizophrenia?, (2) do these technologies interfere with the patient׳s illness?, and (3) do patients envision these technologies being involved in their treatment? We recruited 80 inpatients and outpatients age 18-70 with schizophrenia to complete a brief survey on the prevalence and frequency of cell phone, text messaging, computer, email, and SMN use, and associated attitudes. 56% of subjects use text messaging, 48% have an email account, and 27% of subjects use SMN sites daily, with Facebook being the most popular. Many current users agreed that these technologies help them interact/socialize more, expressed interest in receiving text messages from their doctors, and disagreed that these technologies make symptoms worse. These preliminary findings should be investigated in larger samples, but suggest that these technologies afford a unique opportunity to engage and improve treatment for some patients with schizophrenia.

  2. EXTRACTION OF COPPER FROM LEACH LIQUOR OF METALLIC COMPONENT IN DISCARDED CELL PHONE BY CYANEX® 272

    Directory of Open Access Journals (Sweden)

    ALAFARA A. BABA

    2016-06-01

    Full Text Available Discarded cell phones contribute significantly to the amount of electronic waste generation whilst some of its components are toxic and recoverable. Also, due to the increasing demand for Cu(II in building/construction, electrical and as chemical tool in freshwater, it is imperative to develop low cost and ecofriendly technique as a substitute for the conventional treatments such as reduction-roasting route at elevated temperatures. In the present study, the hydrometallurgical operations involving leaching, solvent extraction and precipitation for the recovery of Cu(II by Cyanex® 272 in kerosene was examined. Various parameters affecting the extraction of Cu(II such as pH, extractant concentration and phase ratio were optimized. At optimal conditions, about 96.3 % Cu(II was extracted into the organic phase by 0.2 mol/L Cyanex® 272 at equilibrium pH 5.0 and aqueous to organic phase ratio 1:1. The stripping of the loaded organic was carried out by 0.1 mol/L HCl solution and stripping efficiency of 98 % was obtained. By McCabe Thiele diagram, four stages are required for complete extraction of Cu(II.

  3. Chemical recycling of cell phone Li-ion batteries: Application in environmental remediation.

    Science.gov (United States)

    Gonçalves, Mariana C Abreu; Garcia, Eric M; Taroco, Hosane A; Gorgulho, Honória F; Melo, Júlio O F; Silva, Rafael R A; Souza, Amauri G

    2015-06-01

    This paper presents, for the first time, the recycling and use of spent Li-ion battery cathode tape as a catalyst in the degradation of an organic dye. In our proposal, two major environmental problems can be solved: the secure disposal of cell phone batteries and the treatment of effluents with potentially toxic organic dyes. The spent Li-ion battery cathode investigated in this paper corresponds to 29% of the mass of Li-ion batteries and is made up of 83% LiCoO2, 14.5% C and less than 2.5% Al, Al2O3 and Co3O4. The use of spent Li-ion battery cathode tape increased the degradation velocity constant of methylene blue in the absence of light by about 200 times in relation to pure H2O2. This increase can be explained by a reduction in the activation energy from 83 kJ mol(-1) to 26 kJ mol(-1). The mechanism of degradation promoted by LiCoO2 is probably related to the generation of superoxide radical (O2(-)). The rupture of the aromatic rings of methylene blue was analyzed by ESI-MS. Copyright © 2015. Published by Elsevier Ltd.

  4. Lifestyle Intervention Using an Internet-Based Curriculum with Cell Phone Reminders for Obese Chinese Teens: A Randomized Controlled Study

    OpenAIRE

    Abraham, Anisha A.; Wing-Chi Chow; Hung-Kwan So; Benjamin Hon-Kei Yip; Albert M Li; Kumta, Shekhar M; Jean Woo; Suk-Mei Chan; Esther Yuet-Ying Lau; E Anthony S Nelson

    2015-01-01

    Objectives Obesity is an increasing public health problem affecting young people. The causes of obesity are multi-factorial among Chinese youth including lack of physical activity and poor eating habits. The use of an internet curriculum and cell phone reminders and texting may be an innovative means of increasing follow up and compliance with obese teens. The objectives of this study were to determine the feasibility of using an adapted internet curriculum and existing nutritional progra...

  5. Cellular Phone Towers, Cell Towers in Lowndes County, GA, Published in 2008, 1:1200 (1in=100ft) scale, Southern Georgia Regional Commission.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:1200 (1in=100ft) scale, was produced all or in part from Other information as of 2008. It is described as 'Cell...

  6. Who actually receives cell phone use while driving citations and how much are these laws enforced among states? A descriptive, cross-sectional study

    National Research Council Canada - National Science Library

    Rudisill, Toni M; Zhu, Motao

    2016-01-01

    While numerous cell phone use while driving laws have been passed among states, little information exists regarding who gets cited for these traffic infractions and how much these laws are enforced...

  7. Cellular Phone Towers, Cell Towers - downloaded from the FCC website, Published in 2010, 1:2400 (1in=200ft) scale, Effingham County Board Of Commissioners.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Other information as of 2010. It is described as 'Cell...

  8. 蓝牙手机室内定位系统%Indoor positioning system for bluetooth cell phone

    Institute of Scientific and Technical Information of China (English)

    张浩; 赵千川

    2011-01-01

    This paper introduced a low-cost platform for locating bluetooth cell phones and releasing position information. The authors improved the scheme of measuring Received Signal Strength Indication ( RSSI) of bluetooth devices lo locate multiple cell phones simultaneously, developed cell phone program to receive position information via Wi-Fi and display it on map. The experimental results show that the system is accurate in positioning and easy to use, and it provides a platform support for applications of Internet of Things (IOT) under current hardware condition.%设计并实现了一种基于蓝牙和Wi-Fi的低成本手机定位和信息发布平台.改进了已有蓝牙设备RSSI检测方案,能对多个手机同时定位;利用Wi-Fi和J2ME技术实现了手机对定位信息的接收和实时显示.实验结果表明系统具有定位准确、使用方便等特点,在目前硬件条件下为物联网应用提供了平台支持.

  9. Impaired energy metabolism of senescent muscle satellite cells is associated with oxidative modifications of glycolytic enzymes

    DEFF Research Database (Denmark)

    Baraibar, Martín A; Hyzewicz, Janek; Rogowska-Wrzesinska, Adelina

    2016-01-01

    Accumulation of oxidized proteins is a hallmark of cellular and organismal aging. Adult muscle stem cell (or satellite cell) replication and differentiation is compromised with age contributing to sarcopenia. However, the molecular events related to satellite cell dysfunction during aging...

  10. Satellite glial cells in sensory ganglia: its role in pain

    Directory of Open Access Journals (Sweden)

    Filipa Alexandra Leite Costa

    2015-02-01

    Full Text Available BACKGROUND AND OBJECTIVES: Satellite glial cells in sensory ganglia are a recent subject of research in the field of pain and a possible therapeutic target in the future. Therefore, the aim of this study was to summarize some of the important physiological and morphological characteristics of these cells and gather the most relevant scientific evidence about its possible role in the development of chronic pain. CONTENT: In the sensory ganglia, each neuronal body is surrounded by satellite glial cells forming distinct functional units. This close relationship enables bidirectional communication via a paracrine signaling between those two cell types. There is a growing body of evidence that glial satellite cells undergo structural and biochemical changes after nerve injury, which influence neuronal excitability and consequently the development and/or maintenance of pain in different animal models of chronic pain. CONCLUSIONS: Satellite glial cells are important in the establishment of physiological pain, in addition to being a potential target for the development of new pain treatments.

  11. Cellular Phone Towers, Cell Phone tower point layer, Published in 2006, 1:1200 (1in=100ft) scale, Town of Cary NC.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:1200 (1in=100ft) scale, was produced all or in part from Published Reports/Deeds information as of 2006. It is...

  12. Cellular Phone Towers, Cell Phone Towers in Thomas County, GA, Published in 2010, 1:4800 (1in=400ft) scale, Thomas County BOC.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:4800 (1in=400ft) scale, was produced all or in part from Hardcopy Maps information as of 2010. It is described as...

  13. “With the cell phone, 24 hours on air”: On gender relations and the appropriation of mobile technologies in low-income groups

    Directory of Open Access Journals (Sweden)

    Sandra Rubia Silva

    2012-12-01

    Full Text Available Drawing from an ethnographic approach, I analyze in this article the appropriation of cell phones in their intersections with gender relations. I discuss the ways by which technology is appropriated to reaffirm love ties, but also becomes the focus of surveillance, tension and conflict. In this sense, I argue that cell phones engender micropolitics of everyday life in which men and women interact in sociocultural dynamics that reflect gender hierarchies, but also subvert them.

  14. Are mobile phones harmful?

    DEFF Research Database (Denmark)

    Blettner, M; Berg, Gabriele

    2000-01-01

    in cells. Implications of these experimental results on public health concerns are yet unclear. Few epidemiological studies are available on the use of mobile phones or on the radiofrequency exposure and the development of cancer. Most of these studies have no or little quantitative exposure data......There is increasing public interest in health risks of mobile phone use. Although there is a vast body of material on the biological effects of radiofrequency fields, current risk assessment is still limited. The article describes several hypotheses and results of biological effects such as thermal...... and they are limited by the small number of observations. Large epidemiological studies are necessary in order to investigate the use of mobile phones on the development of cancer. It should be emphasized that even a small elevated risk may have a large implication for public health, as the use of mobile phones...

  15. Effect of an Educational Program Based on the Health Belief Model to Reduce Cell Phone Usage During Driving in Taxi drivers

    Directory of Open Access Journals (Sweden)

    Babak Moeini

    2014-09-01

    Full Text Available Introduction: Cell phone usage during driving has become a threat to traffic safety. This study aimed to determine the effectiveness of an educational program based on the health belief model to reduce cell phone usage during driving in taxi drivers of Tuyserkan. Materials and Methods: In this quasi-experimental study, 110 taxi drivers younger than 35 years were randomly divided into two experimental and control groups in Tuyserkan, Iran. Data was collected using a questionnaire including the health belief model constructs, knowledge, behaviors of using cell phone and demographic variables. The questionnaires were self-reported. Intervention was three sessions applied in the experimental group. Both groups were followed for two months after the intervention. Finally, data analysis was performed using SPSS- 19 by Chi-square, Independent T-test, Paired T-test and McNemar. Results: The mean scores for the constructs of health belief model (perceived susceptibility, severity, barriers, perceived benefits, self-efficacy and cues to action, knowledge and desired behaviors about the use of cell phone during driving showed no significant differences between the two groups before the intervention. After the educational intervention, significant differences were observed in experimental group compared to control group. After educational intervention, cell phone usage reduced by 35.14% in the experimental group. Conclusion: An educational intervention based on the health belief model could reduce cell phone usage during driving in taxi drivers.

  16. Surveying the relationship of Internet addiction with dependence on cell phone, depression, anxiety, and stress in collegians (Case study: Bam University of Medical Sciences

    Directory of Open Access Journals (Sweden)

    Asra Nassehi

    2016-06-01

    Full Text Available Background and objectives: A considerable increase in using the Internet and cell phone is evident especially among university students. On the other hand, the attention and concerns expressed about the psychological and social effects of long-term use of communicational technologies and the, probably negative, effects on professional future and social relationships are growing. Therefore, the present study is aimed at determining the relationship of Internet addiction with excessive dependence on cell phone, depression, anxiety, and stress in the students of Bam University of Medical Sciences. Methodology: A comparative-correlative study on 230 students in Bam University of Medical Sciences was carried out in 2014. The data was collected using Young’s Internet Addiction Test (IAT, dependence of cell phone, and Lovibond & Lovibond’s depression, anxiety and stress scale (DASS-21. (sig. = 0.05 Finding: Total scores of Internet addiction and dependence on cell phone were 49.03±20 and 42.7±11.77 respectively. There was also a significant relationship between Internet addiction and the variables dependence on cell phone, depression, anxiety, and stress. (p<0.05 Conclusion: The results showed that increase in the time spent on the Internet led to increase in depression, anxiety, stress, and dependence on cell phone. Therefore, there is a need for more efficient educational, consultation, and behavioral planning to attenuate the psychological and social damages.

  17. The use of cell phones and radio communication systems to reduce delays in getting help for pregnant women in low- and middle-income countries: a scoping review

    Directory of Open Access Journals (Sweden)

    Sunday O. Oyeyemi

    2015-09-01

    Full Text Available Background: Delays in getting medical help are important factors in the deaths of many pregnant women and unborn children in the low- and middle-income countries (LMIC. Studies have suggested that the use of cell phones and radio communication systems might reduce such delays. Objectives: We review the literature regarding the impact of cell phones and radio communication systems on delays in getting medical help by pregnant women in the LMIC. Design: Cochrane Library, PubMed, Maternity and Infant care (Ovid, Web of Science (ISI, and Google Scholar were searched for studies relating to the use of cell phones for maternal and child health services, supplemented with hand searches. We included studies in LMIC and in English involving the simple use of cell phones (or radio communication to either make calls or send text messages. Results: Fifteen studies met the inclusion criteria. All the studies, while of various designs, demonstrated positive contributory effects of cell phones or radio communication systems in reducing delays experienced by pregnant women in getting medical help. Conclusions: While the results suggested that cell phones could contribute in reducing delays, more studies of a longer duration are needed to strengthen the finding.

  18. Satellite cell depletion prevents fiber hypertrophy in skeletal muscle.

    Science.gov (United States)

    Egner, Ingrid M; Bruusgaard, Jo C; Gundersen, Kristian

    2016-08-15

    The largest mammalian cells are the muscle fibers, and they have multiple nuclei to support their large cytoplasmic volumes. During hypertrophic growth, new myonuclei are recruited from satellite stem cells into the fiber syncytia, but it was recently suggested that such recruitment is not obligatory: overload hypertrophy after synergist ablation of the plantaris muscle appeared normal in transgenic mice in which most of the satellite cells were abolished. When we essentially repeated these experiments analyzing the muscles by immunohistochemistry and in vivo and ex vivo imaging, we found that overload hypertrophy was prevented in the satellite cell-deficient mice, in both the plantaris and the extensor digitorum longus muscles. We attribute the previous findings to a reliance on muscle mass as a proxy for fiber hypertrophy, and to the inclusion of a significant number of regenerating fibers in the analysis. We discuss that there is currently no model in which functional, sustainable hypertrophy has been unequivocally demonstrated in the absence of satellite cells; an exception is re-growth, which can occur using previously recruited myonuclei without addition of new myonuclei. © 2016. Published by The Company of Biologists Ltd.

  19. 3D printed disposable optics and lab-on-a-chip devices for chemical sensing with cell phones

    Science.gov (United States)

    Comina, G.; Suska, A.; Filippini, D.

    2017-02-01

    Digital manufacturing (DM) offers fast prototyping capabilities and great versatility to configure countless architectures at affordable development costs. Autonomous lab-on-a-chip (LOC) devices, conceived as only disposable accessory to interface chemical sensing to cell phones, require specific features that can be achieved using DM techniques. Here we describe stereo-lithography 3D printing (SLA) of optical components and unibody-LOC (ULOC) devices using consumer grade printers. ULOC devices integrate actuation in the form of check-valves and finger pumps, as well as the calibration range required for quantitative detection. Coupling to phone camera readout depends on the detection approach, and includes different types of optical components. Optical surfaces can be locally configured with a simple polishing-free post-processing step, and the representative costs are 0.5 US$/device, same as ULOC devices, both involving fabrication times of about 20 min.

  20. Neonatal Satellite Cells Form Small Myotubes in Vitro

    NARCIS (Netherlands)

    Carvajal Monroy, P.L.; Grefte, S.; Kuijpers-Jagtman, A.M.; Den Hoff, Von J.W.; Wagener, F.A.D.T.G.

    2017-01-01

    Although palatal muscle reconstruction in patients with cleft palate takes place during early childhood, normal speech development is often not achieved. We hypothesized that the intrinsic properties of head satellite cells (SCs) and the young age of these patients contribute to the poor muscle

  1. Are computer and cell phone use associated with body mass index and overweight? A population study among twin adolescents

    Directory of Open Access Journals (Sweden)

    Pulkkinen Lea

    2007-02-01

    Full Text Available Abstract Background Overweight in children and adolescents has reached dimensions of a global epidemic during recent years. Simultaneously, information and communication technology use has rapidly increased. Methods A population-based sample of Finnish twins born in 1983–1987 (N = 4098 was assessed by self-report questionnaires at 17 y during 2000–2005. The association of overweight (defined by Cole's BMI-for-age cut-offs with computer and cell phone use and ownership was analyzed by logistic regression and their association with BMI by linear regression models. The effect of twinship was taken into account by correcting for clustered sampling of families. All models were adjusted for gender, physical exercise, and parents' education and occupational class. Results The proportion of adolescents who did not have a computer at home decreased from 18% to 8% from 2000 to 2005. Compared to them, having a home computer (without an Internet connection was associated with a higher risk of overweight (odds ratio 2.3, 95% CI 1.4 to 3.8 and BMI (beta coefficient 0.57, 95% CI 0.15 to 0.98. However, having a computer with an Internet connection was not associated with weight status. Belonging to the highest quintile (OR 1.8 95% CI 1.2 to 2.8 and second-highest quintile (OR 1.6 95% CI 1.1 to 2.4 of weekly computer use was positively associated with overweight. The proportion of adolescents without a personal cell phone decreased from 12% to 1% across 2000 to 2005. There was a positive linear trend of increasing monthly phone bill with BMI (beta 0.18, 95% CI 0.06 to 0.30, but the association of a cell phone bill with overweight was very weak. Conclusion Time spent using a home computer was associated with an increased risk of overweight. Cell phone use correlated weakly with BMI. Increasing use of information and communication technology may be related to the obesity epidemic among adolescents.

  2. A rear-end collision risk assessment model based on drivers' collision avoidance process under influences of cell phone use and gender-A driving simulator based study.

    Science.gov (United States)

    Li, Xiaomeng; Yan, Xuedong; Wu, Jiawei; Radwan, Essam; Zhang, Yuting

    2016-12-01

    Driver's collision avoidance performance has a direct link to the collision risk and crash severity. Previous studies demonstrated that the distracted driving, such as using a cell phone while driving, disrupted the driver's performance on road. This study aimed to investigate the manner and extent to which cell phone use and driver's gender affected driving performance and collision risk in a rear-end collision avoidance process. Forty-two licensed drivers completed the driving simulation experiment in three phone use conditions: no phone use, hands-free, and hand-held, in which the drivers drove in a car-following situation with potential rear-end collision risks caused by the leading vehicle's sudden deceleration. Based on the experiment data, a rear-end collision risk assessment model was developed to assess the influence of cell phone use and driver's gender. The cell phone use and driver's gender were found to be significant factors that affected the braking performances in the rear-end collision avoidance process, including the brake reaction time, the deceleration adjusting time and the maximum deceleration rate. The minimum headway distance between the leading vehicle and the simulator during the rear-end collision avoidance process was the final output variable, which could be used to measure the rear-end collision risk and judge whether a collision occurred. The results showed that although cell phone use drivers took some compensatory behaviors in the collision avoidance process to reduce the mental workload, the collision risk in cell phone use conditions was still higher than that without the phone use. More importantly, the results proved that the hands-free condition did not eliminate the safety problem associated with distracted driving because it impaired the driving performance in the same way as much as the use of hand-held phones. In addition, the gender effect indicated that although female drivers had longer reaction time than male drivers in

  3. Headset Bluetooth and cell phone based continuous central body temperature measurement system.

    Science.gov (United States)

    Sanches, J Miguel; Pereira, Bruno; Paiva, Teresa

    2010-01-01

    The accurate measure of the central temperature is a very important physiologic indicator in several clinical applications, namely, in the characterization and diagnosis of sleep disorders. In this paper a simple system is described to continuously measure the body temperature at the ear. An electronic temperature sensor is coupled to the microphone of a common commercial auricular Bluetooth device that sends the temperature measurements to a mobile phone to which is paired. The measurements are stored at the mobile phone and periodically sent to a medical facility by email or SMS (short messaging service).

  4. Substrate elasticity affects bovine satellite cell activation kinetics in vitro.

    Science.gov (United States)

    Lapin, M R; Gonzalez, J M; Johnson, S E

    2013-05-01

    Satellite cells support efficient postnatal skeletal muscle hypertrophy through fusion into the adjacent muscle fiber. Nuclear contribution allows for maintenance of the fiber myonuclear domain and proficient transcription of myogenic genes. Niche growth factors affect satellite cell biology; however, the interplay between fiber elasticity and microenvironment proteins remains largely unknown. The objective of the experiment was to examine the effects of hepatocyte growth factor (HGF) and surface elasticity on bovine satellite cell (BSC) activation kinetics in vitro. Young's elastic modulus was calculated for the semimembranosus (SM) and LM muscles of young bulls (5 d; n = 8) and adult cows (27 mo; n = 4) cattle. Results indicate that LM elasticity decreased (P Young's modulus for the SM was noted. Bovine satellite cells were seeded atop polyacrylamide bioscaffolds with surface elasticities that mimic young bull and adult cow LM or traditional cultureware. Cells were maintained in low-serum media supplemented with 5 ng/mL HGF or vehicle only for 24 or 48 h. Activation was evaluated by proliferating cell nuclear antigen (PCNA) immunocytochemistry. Results indicate that BSC maintained on rigid surfaces were activated at 24 h and refractive to HGF supplementation. By contrast, fewer (P young bull (8.1 ± 1.7 kPa) or adult cow (14.6 ± 1.6 kPa) LM. Supplementation with HGF promoted activation of BSC cultured on bioscaffolds as measured by an increase (P muscle stem cells (P > 0.05). However, with increasing surface elasticity, an increase (P muscle progenitors was observed. These results confirm that biophysical and biochemical signals regulate BSC activation.

  5. Age-dependent tissue-specific exposure of cell phone users

    Energy Technology Data Exchange (ETDEWEB)

    Christ, Andreas; Gosselin, Marie-Christine; Kuehn, Sven; Kuster, Niels [Foundation for Research on Information Technologies in Society (IT' IS), Zeughausstr. 43, 8004 Zuerich (Switzerland); Christopoulou, Maria [National Technical University of Athens, School of Electrical and Computer Engineering, 9 Iroon Polytechniou Str., 15780 Athens (Greece)], E-mail: christ@itis.ethz.ch

    2010-04-07

    The peak spatial specific absorption rate (SAR) assessed with the standardized specific anthropometric mannequin head phantom has been shown to yield a conservative exposure estimate for both adults and children using mobile phones. There are, however, questions remaining concerning the impact of age-dependent dielectric tissue properties and age-dependent proportions of the skull, face and ear on the global and local absorption, in particular in the brain tissues. In this study, we compare the absorption in various parts of the cortex for different magnetic resonance imaging-based head phantoms of adults and children exposed to different models of mobile phones. The results show that the locally induced fields in children can be significantly higher (>3 dB) in subregions of the brain (cortex, hippocampus and hypothalamus) and the eye due to the closer proximity of the phone to these tissues. The increase is even larger for bone marrow (>10 dB) as a result of its significantly high conductivity. Tissues such as the pineal gland show no increase since their distances to the phone are not a function of age. This study, however, confirms previous findings saying that there are no age-dependent changes of the peak spatial SAR when averaged over the entire head.

  6. Maternal cell phone use in early pregnancy and child's language, communication and motor skills at 3 and 5 years: the Norwegian mother and child cohort study (MoBa).

    Science.gov (United States)

    Papadopoulou, Eleni; Haugen, Margaretha; Schjølberg, Synnve; Magnus, Per; Brunborg, Gunnar; Vrijheid, Martine; Alexander, Jan

    2017-09-05

    Cell phone use during pregnancy is a public health concern. We investigated the association between maternal cell phone use in pregnancy and child's language, communication and motor skills at 3 and 5 years. This prospective study includes 45,389 mother-child pairs, participants of the MoBa, recruited at mid-pregnancy from 1999 to 2008. Maternal frequency of cell phone use in early pregnancy and child language, communication and motor skills at 3 and 5 years, were assessed by questionnaires. Logistic regression was used to estimate the associations. No cell phone use in early pregnancy was reported by 9.8% of women, while 39%, 46.9% and 4.3% of the women were categorized as low, medium and high cell phone users. Children of cell phone user mothers had 17% (OR = 0.83, 95% CI: 0.77, 0.89) lower adjusted risk of having low sentence complexity at 3 years, compared to children of non-users. The risk was 13%, 22% and 29% lower by low, medium and high maternal cell phone use. Additionally, children of cell phone users had lower risk of low motor skills score at 3 years, compared to children of non-users, but this association was not found at 5 years. We found no association between maternal cell phone use and low communication skills. We reported a decreased risk of low language and motor skills at three years in relation to prenatal cell phone use, which might be explained by enhanced maternal-child interaction among cell phone users. No evidence of adverse neurodevelopmental effects of prenatal cell phone use was reported.

  7. Outdoor and indoor sources of residential radiofrequency electromagnetic fields, personal cell phone and cordless phone use, and cognitive function in 5-6 years old children

    NARCIS (Netherlands)

    Guxens, Mònica; Vermeulen, Roel; van Eijsden, Manon; Beekhuizen, Johan; Vrijkotte, Tanja G M; van Strien, Rob T; Kromhout, Hans; Huss, Anke

    2016-01-01

    BACKGROUND: Little is known about the exposure of young children to radiofrequency electromagnetic fields (RF-EMF) and potentially associated health effects. We assessed the relationship between residential RF-EMF exposure from mobile phone base stations, residential presence of indoor sources, pers

  8. Effects of 3G cell phone exposure on the structure and function of the human cytochrome P450 reductase.

    Science.gov (United States)

    Tanvir, Shazia; Thuróczy, György; Selmaoui, Brahim; Silva Pires Antonietti, Viviane; Sonnet, Pascal; Arnaud-Cormos, Delia; Lévêque, Philippe; Pulvin, Sylviane; de Seze, René

    2016-10-01

    Cell phones increase exposure to radiofrequency (RF) electromagnetic fields (EMFs). Whether EMFs exert specific effects on biological systems remains debatable. This study investigated the effect of cell phone exposure on the structure and function of human NADPH-cytochrome P450 reductase (CPR). CPR plays a key role in the electron transfer to cytochrome P450, which takes part in a wide range of oxidative metabolic reactions in various organisms from microbes to humans. Human CPR was exposed for 60min to 1966-MHz RF inside a transverse electromagnetic cell (TEM-cell) placed in an incubator. The specific absorption rate (SAR) was 5W·kg(-1). Conformation changes have been detected through fluorescent spectroscopy of flavin and tryptophan residues, and investigated through circular dichroism, dynamic light scattering and microelectrophoresis. These showed that CPR was narrowed. By using cytochrome C reductase activity to assess the electron flux through the CPR, the Michaelis Menten constant (Km) and the maximum initial velocity (Vmax) decreased by 22% as compared with controls. This change was due to small changes in the tertiary and secondary structures of the protein at 37°C. The relevance of these findings to an actual RF exposure scenario demands further biochemical and in-vivo confirmation.

  9. The Effect of 217 Hz Magnetic Field of Cell Phone with Different Intensities on Apoptosis of Normal and Cancerous Cells Treated with Chemotherapy Drug

    Directory of Open Access Journals (Sweden)

    Mahsa Mansourian

    2012-03-01

    Full Text Available Background: According to the increasing development of home and business electronic equipment in today's world, the biological effects of ELF magnetic fields have been studied at two molecular-cellular and animal- human levels. Considering the therapeutic viewpoint of this study regarding the effects of low-frequency fields of mobile phone, the effect of acute exposure to this field on chemotherapy will be studied.Materials and Methods: In this experimental study, based on measurement of the intensity of the magnetic fields from mobile phones in another research, flux densities of magnetic field of 159.44, 93.25 and 120µ tesla with frequency of 217Hz was generated in magnetic field generator system, and the apoptosis level in K562 cancer cells and healthy cells of lymphocytes was assessed after exposure to field using flow cytometry method. This evaluation method was also performed for the cells treated with bleomycin after exposure to this field.Results: 217 Hz magnetic field exposure significantly increases the rate of apoptosis percentage (p > 0.05 in K562 cancer cells and in two intensities of 120 and 159.44µ tesla compared to the control group, but such effect is not observed in lymphocyte cells. Bleomycin-induced apoptosis percentage following exposure to the mentioned magnetic field shows no significant difference compared to the group of treatment with drug and without field exposure. This lack of significant difference is observed between the groups of drug after field exposure and field alone as well as between groups exposed to field and groups treated with bleomycin.Conclusion: Study results showed that 217 Hz magnetic field of mobile phone can induce apoptosis on cancer cells, but it has no effect on healthy cells. Thus, in order to use mobile phone as an effective factor in their treatment, some studies should be conducted at animal-human level.

  10. Discarded cell phone lithium ion batteries state of health quick method analysis by galvanostatic intermittent titration technique (GITT concept

    Directory of Open Access Journals (Sweden)

    Paulo Rogério Catarini

    2009-03-01

    Full Text Available The state of health (SOH is a important evaluation parameter to rechargeable batteries, because determine its cycle life and help on electric devices supplied by batteries maintenance. In this work the lithium ion discards cell phones batteries state of health and apparent diffusion coefficient (Dap were measured and correlated which purpose is diminish the batteries analyze time. The apparent diffusion coefficient is a ionic diffusion coefficient modification from GITT technique. The SOH and Dap correlation is well behaved, disclosing a cubic dependency. The time analyze was reduced by more than 1 h.

  11. Trends in Scientific Literature on Addiction to the Internet, Video Games, and Cell Phones from 2006 to 2010

    Science.gov (United States)

    Carbonell, Xavier; Guardiola, Elena; Fuster, Héctor; Gil, Frederic; Panova, Tayana

    2016-01-01

    Background: The goals of the present work were to retrieve the scientific articles published on addiction to the Internet, video games, and cell phones and to analyze the pattern of publications in this area (who is doing the research, when and where it is taking place, and in which journals it is being published), to determine the research being conducted as well as to document geographical trends in publication over time in three types of technological addictions: Internet, cell phones, and video games. Methods: Articles indexed in PubMed and PsycINFO between 2006 and 2010 related to the pathological use of Internet, cell phones, and video games were retrieved. Search results were reviewed to eliminate articles that were not relevant or were duplicates. Results: Three hundred and thirty valid articles were retrieved from PubMed and PsycINFO from 2006 to 2010. Results were compared with those of 1996–2005. The year with the highest number of articles published was 2008 (n = 96). The most productive countries, in terms of number of articles published, were China (n = 67), the United States (n = 56), the United Kingdom (n = 47), and Taiwan (n = 33). The most commonly used language was English (70.3%), followed by Chinese (15.4%). Articles were published in 153 different journals. The journal that published the most articles was Cyberpsychology and Behavior (n = 73), followed by Chinese Journal of Clinical Psychology (n = 27) and International Journal of Mental Health and Addiction (n = 16). Internet was the area most frequently studied, with an increasing interest in other areas such as online video games and cell phones. Conclusions: The number of publications on technological addictions reached a peak in 2008. The scientific contributions of China, Taiwan, and Korea are overrepresented compared to other scientific fields such as drug addiction. The inclusion of Internet Gaming Disorder in the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition

  12. HEDONIC ANALYSIS OF CELL PHONES SOLD WITH POST-PAID SERVICE PLANS IN BRAZIL

    Directory of Open Access Journals (Sweden)

    Cláudio R. Lucinda

    2012-07-01

    Full Text Available The aim of this paper is to analyze the determining factors for the pricing of handsets sold with service plans, using the hedonic price method. This was undertaken by building a database comprising 48 handset models, under nine different service plans, over a period of 53 weeks in 2008, and resulted in 27 different attributes and a total number of nearly 300,000 data registers. The results suggest that the value of monthly subscriptions and calling minutes are important to explain the prices of handsets. Furthermore, both the physical volume and number of megapixels of a camera had an effect on the prices. The bigger the handset, the cheaper it becomes, and the more megapixels a camera phone has, the more expensive it becomes. Additionally, it was found that in 2008 Brazilian phone companies were subsidizing enabled data connection handsets.

  13. Cell phone-supported cognitive behavioural therapy for anxiety disorders: a protocol for effectiveness studies in frontline settings

    Directory of Open Access Journals (Sweden)

    Fröberg Anders

    2011-01-01

    Full Text Available Abstract Background Reviews of randomized controlled trials (RCTs of cognitive behavioural therapy (CBT for anxiety disorders have reported large pre- to post-treatment within-group effect sizes on measures of anxiety when supplied in therapist consultations and in technology-supported settings. However, the stringent experimental control of RCTs results in a lack of external validity, which limits the generalizability of findings to real-world frontline clinical practice. We set out to examine the specification of a protocol for study of the effectiveness of cell phone-supported CBT for in situ management of anxiety disorders. Methods and design Nominal group methods were used for requirements analysis and protocol design. Making a distinction between different forms of technology-supported therapy, examination of therapists' role, and implementing trials in existing organizational and community contexts were found to be the central requirements in the protocol. Discussion The resulting protocol (NCT01205191 at clinicaltrials.gov for use in frontline clinical practice in which effectiveness, adherence, and the role of the therapists are analyzed, provides evidence for what are truly valuable cell phone-supported CBT treatments and guidance for the broader introduction of CBT in health services.

  14. Usages Pattern of Cell Phone in Classroom: A Case Study of Mathematical and Physical Science Faculty Students of Jahangirnagar University

    Science.gov (United States)

    Miah, Md. Shiblu; Hossain, Md. Moyazzem; Rahman, Md. Habibur

    2017-01-01

    Now-a-days mobile phone is very important communicational device. This cableless device reduces the hazards of the land phone. In spite of its various advantages it has some disadvantages also. Misusing of mobile phone increases the disadvantages of this device day by day. Unnecessary talking makes the reasons of wasting the money and time for the…

  15. RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells.

    Science.gov (United States)

    Vasyutina, Elena; Lenhard, Diana C; Wende, Hagen; Erdmann, Bettina; Epstein, Jonathan A; Birchmeier, Carmen

    2007-03-13

    In the developing muscle, a pool of myogenic progenitor cells is formed and maintained. These resident progenitors provide a source of cells for muscle growth in development and generate satellite cells in the perinatal period. By the use of conditional mutagenesis in mice, we demonstrate here that the major mediator of Notch signaling, the transcription factor RBP-J, is essential to maintain this pool of progenitor cells in an undifferentiated state. In the absence of RBP-J, these cells undergo uncontrolled myogenic differentiation, leading to a depletion of the progenitor pool. This results in a lack of muscle growth in development and severe muscle hypotrophy. In addition, satellite cells are not formed late in fetal development in conditional RBP-J mutant mice. We conclude that RBP-J is required in the developing muscle to set aside proliferating progenitors and satellite cells.

  16. Muscle Interstitial Cells: A Brief Field Guide to Non-satellite Cell Populations in Skeletal Muscle.

    Science.gov (United States)

    Tedesco, Francesco Saverio; Moyle, Louise A; Perdiguero, Eusebio

    2017-01-01

    Skeletal muscle regeneration is mainly enabled by a population of adult stem cells known as satellite cells. Satellite cells have been shown to be indispensable for adult skeletal muscle repair and regeneration. In the last two decades, other stem/progenitor cell populations resident in the skeletal muscle interstitium have been identified as "collaborators" of satellite cells during regeneration. They also appear to have a key role in replacing skeletal muscle with adipose, fibrous, or bone tissue in pathological conditions. Here, we review the role and known functions of these different interstitial skeletal muscle cell types and discuss their role in skeletal muscle tissue homeostasis, regeneration, and disease, including their therapeutic potential for cell transplantation protocols.

  17. Determination of the Predictive role of Self-Regulation and Self-Control on Intemperate Use of Cell Phones by Students

    Directory of Open Access Journals (Sweden)

    S. Pourrazavi

    2015-07-01

    Full Text Available Introduction & Objective: Regarding increasing the rate of cell phones use and its' subsequent dependency in such instrument among young people and also considering the important role of self-regulation and self-control traits on health related issues and the roles of such issues in problematic and addictive behaviors, this study has been designed to evaluate the predictive role of self-regulation and self-control on the intemperate use of cell phone and its related de-pendencies. Materials & Methods: This study was a cross-sectional study with analytical and descriptive orientation which has been carried out the students of universities which were located in the Tabriz city, Iran in 2013. Data were gathered through a questionnaire that was filled by 476 students (190 male and 286 female. Participants were selected through a multi-stage cluster sampling method from 9 universities in Tabriz. Data analysis was performed by SPSS version 21 and Mplus software version 6.2. Results: Results showed that the predictive effect of self-regulation (P= 0.19 and self-control (P=0.41 on intemperate cell phone use was not significant, hence the increase of one unit in self-regulation and self-control respectively reduced 42.0, 87.0 dependency in cell phone. Conclusion: The present study could not demonstrate the predictive effect of self-regulation and self-control on intemperate cell phones use, however, the results showed that the meas-ures were relatively correlated with dependency in cell phone and therefore further researches seem to be necessary in this field.(Sci J Hamadan Univ Med Sci 2015; 22 (2: 152-160

  18. Use of email, cell phone and text message between patients and primary-care physicians: cross-sectional study in a French-speaking part of Switzerland.

    Science.gov (United States)

    Dash, Jonathan; Haller, Dagmar M; Sommer, Johanna; Junod Perron, Noelle

    2016-10-05

    Physicians' daily work is increasingly affected by the use of emails, text messages and cell phone calls with their patients. The aim of this study was to describe their use between primary-care physicians and patients in a French-speaking part of Switzerland. A cross-sectional mail survey was conducted among all primary-care physicians of Geneva canton (n = 636). The questionnaire focused on the frequency of giving access to, type of use, advantages and disadvantages of email, cell phone calls and text messages communication between physicians and patients. Six hundred thirty-six questionnaires were mailed, 412 (65 %) were returned and 372 (58 %) could be analysed (37 refusals and three blanks). Seventy-two percent physicians gave their email-address and 74 % their cell phone number to their patients. Emails were used to respond to patients' questions (82 %) and change appointments (72 %) while cell phone calls and text messages were used to follow patients' health conditions. Sixty-four percent of those who used email communication never discussed the rules for email exchanges, and 54 % did not address confidentiality issues with their patients. Most commonly identified advantages of emails, cell phone calls and text messages were improved relationship with the patient, saving time (for emails) and improving the follow-up (for cell phone and text messages). The main disadvantages included misuse by the patient, interference with private life and lack of reimbursement. These tools are widely used by primary-care physicians with their patients. More attention should be paid to confidentiality, documentation and reimbursement when using email communication in order to optimize its use.

  19. PhoneSat - The Smartphone Nanosatellite

    Science.gov (United States)

    Westley, Deborah; Yost, Bruce; Petro, Andrew

    2013-01-01

    PhoneSat 2.4, carried into space on November 19, 2013 aboard a Minotaur I rocket from the Mid-Atlantic Regional Spaceport at NASAs Wallops Flight Facility in Virginia, is the first of the PhoneSat family to use a two-way S-band radio to allow engineers to command the satellite from Earth. This mission also serves as a technology demonstration for a novel attitude determination and control system (ADCS) that establishes and stabilizes the satellites attitude relative to Earth. Unlike the earlier PhoneSats that used a Nexus One, PhoneSat 2.4 uses the Nexus S smartphone, which runs Googles Android operating system, and is made by Samsung Electronics Co., Suwon, So. Korea. The smartphone provides many of the functions needed by the satellite such as a central computer, data memory, ready-made interfaces for communications, navigation and power all pre-assembled in a rugged electronics package.

  20. The satellite cell in male and female, developing and adult mouse muscle: distinct stem cells for growth and regeneration.

    Directory of Open Access Journals (Sweden)

    Alice Neal

    Full Text Available Satellite cells are myogenic cells found between the basal lamina and the sarcolemma of the muscle fibre. Satellite cells are the source of new myofibres; as such, satellite cell transplantation holds promise as a treatment for muscular dystrophies. We have investigated age and sex differences between mouse satellite cells in vitro and assessed the importance of these factors as mediators of donor cell engraftment in an in vivo model of satellite cell transplantation. We found that satellite cell numbers are increased in growing compared to adult and in male compared to female adult mice. We saw no difference in the expression of the myogenic regulatory factors between male and female mice, but distinct profiles were observed according to developmental stage. We show that, in contrast to adult mice, the majority of satellite cells from two week old mice are proliferating to facilitate myofibre growth; however a small proportion of these cells are quiescent and not contributing to this growth programme. Despite observed changes in satellite cell populations, there is no difference in engraftment efficiency either between satellite cells derived from adult or pre-weaned donor mice, male or female donor cells, or between male and female host muscle environments. We suggest there exist two distinct satellite cell populations: one for muscle growth and maintenance and one for muscle regeneration.

  1. Neglect in Human Communication: Quantifying the Cost of Cell-Phone Interruptions in Face to Face Dialogs

    Science.gov (United States)

    Lopez-Rosenfeld, Matías; Calero, Cecilia I.; Fernandez Slezak, Diego; Garbulsky, Gerry; Bergman, Mariano; Trevisan, Marcos; Sigman, Mariano

    2015-01-01

    There is a prevailing belief that interruptions using cellular phones during face to face interactions may affect severely how people relate and perceive each other. We set out to determine this cost quantitatively through an experiment performed in dyads, in a large audience in a TEDx event. One of the two participants (the speaker) narrates a story vividly. The listener is asked to deliberately ignore the speaker during part of the story (for instance, attending to their cell-phone). The speaker is not aware of this treatment. We show that total amount of attention is the major factor driving subjective beliefs about the story and the conversational partner. The effects are mostly independent on how attention is distributed in time. All social parameters of human communication are affected by attention time with a sole exception: the perceived emotion of the story. Interruptions during day-to-day communication between peers are extremely frequent. Our data should provide a note of caution, by indicating that they have a major effect on the perception people have about what they say (whether it is interesting or not . . .) and about the virtues of the people around them. PMID:26039326

  2. Neglect in human communication: quantifying the cost of cell-phone interruptions in face to face dialogs.

    Science.gov (United States)

    Lopez-Rosenfeld, Matías; Calero, Cecilia I; Fernandez Slezak, Diego; Garbulsky, Gerry; Bergman, Mariano; Trevisan, Marcos; Sigman, Mariano

    2015-01-01

    There is a prevailing belief that interruptions using cellular phones during face to face interactions may affect severely how people relate and perceive each other. We set out to determine this cost quantitatively through an experiment performed in dyads, in a large audience in a TEDx event. One of the two participants (the speaker) narrates a story vividly. The listener is asked to deliberately ignore the speaker during part of the story (for instance, attending to their cell-phone). The speaker is not aware of this treatment. We show that total amount of attention is the major factor driving subjective beliefs about the story and the conversational partner. The effects are mostly independent on how attention is distributed in time. All social parameters of human communication are affected by attention time with a sole exception: the perceived emotion of the story. Interruptions during day-to-day communication between peers are extremely frequent. Our data should provide a note of caution, by indicating that they have a major effect on the perception people have about what they say (whether it is interesting or not . . .) and about the virtues of the people around them.

  3. Neglect in human communication: quantifying the cost of cell-phone interruptions in face to face dialogs.

    Directory of Open Access Journals (Sweden)

    Matías Lopez-Rosenfeld

    Full Text Available There is a prevailing belief that interruptions using cellular phones during face to face interactions may affect severely how people relate and perceive each other. We set out to determine this cost quantitatively through an experiment performed in dyads, in a large audience in a TEDx event. One of the two participants (the speaker narrates a story vividly. The listener is asked to deliberately ignore the speaker during part of the story (for instance, attending to their cell-phone. The speaker is not aware of this treatment. We show that total amount of attention is the major factor driving subjective beliefs about the story and the conversational partner. The effects are mostly independent on how attention is distributed in time. All social parameters of human communication are affected by attention time with a sole exception: the perceived emotion of the story. Interruptions during day-to-day communication between peers are extremely frequent. Our data should provide a note of caution, by indicating that they have a major effect on the perception people have about what they say (whether it is interesting or not . . . and about the virtues of the people around them.

  4. Selenium reduces mobile phone (900 MHz)-induced oxidative stress, mitochondrial function, and apoptosis in breast cancer cells.

    Science.gov (United States)

    Kahya, Mehmet Cemal; Nazıroğlu, Mustafa; Çiğ, Bilal

    2014-08-01

    Exposure to mobile phone-induced electromagnetic radiation (EMR) may affect biological systems by increasing free oxygen radicals, apoptosis, and mitochondrial depolarization levels although selenium may modulate the values in cancer. The present study was designed to investigate the effects of 900 MHz radiation on the antioxidant redox system, apoptosis, and mitochondrial depolarization levels in MDA-MB-231 breast cancer cell line. Cultures of the cancer cells were divided into four main groups as controls, selenium, EMR, and EMR + selenium. In EMR groups, the cells were exposed to 900 MHz EMR for 1 h (SAR value of the EMR was 0.36 ± 0.02 W/kg). In selenium groups, the cells were also incubated with sodium selenite for 1 h before EMR exposure. Then, the following values were analyzed: (a) cell viability, (b) intracellular ROS production, (c) mitochondrial membrane depolarization, (d) cell apoptosis, and (e) caspase-3 and caspase-9 values. Selenium suppressed EMR-induced oxidative cell damage and cell viability (MTT) through a reduction of oxidative stress and restoring mitochondrial membrane potential. Additionally, selenium indicated anti-apoptotic effects, as demonstrated by plate reader analyses of apoptosis levels and caspase-3 and caspase-9 values. In conclusion, 900 MHz EMR appears to induce apoptosis effects through oxidative stress and mitochondrial depolarization although incubation of selenium seems to counteract the effects on apoptosis and oxidative stress.

  5. Effect of 935-MHz phone-simulating electromagnetic radiation on endometrial glandular cells during mouse embryo implantation.

    Science.gov (United States)

    Liu, Wenhui; Zheng, Xinmin; Qu, Zaiqing; Zhang, Ming; Zhou, Chun; Ma, Ling; Zhang, Yuanzhen

    2012-10-01

    This study examined the impact of 935MHz phone-simulating electromagnetic radiation on embryo implantation of pregnant mice. Each 7-week-old Kunming (KM) female white mouse was set up with a KM male mouse in a single cage for mating overnight after induction of ovulation. In the first three days of pregnancy, the pregnant mice was exposed to electromagnetic radiation at low-intensity (150 μW/cm(2), ranging from 130 to 200 μW/cm(2), for 2- or 4-h exposure every day), mid-intensity (570 μW/cm(2), ranging from 400 to 700 μW/cm(2), for 2- or 4-h exposure every day) or high-intensity (1400 μW/cm(2), ranging from 1200 to 1500 μW/cm(2), for 2- or 4-h exposure every day), respectively. On the day 4 after gestation (known as the window of murine embryo implantation), the endometrium was collected and the suspension of endometrial glandular cells was made. Laser scanning microscopy was employed to detect the mitochondrial membrane potential and intracellular calcium ion concentration. In high-intensity, 2- and 4-h groups, mitochondrial membrane potential of endometrial glandular cells was significantly lower than that in the normal control group (Pelectromagnetic radiation and longer length of the radiation are required to inflict a remarkable functional and structural damage to mitochondrial membrane. Our data demonstrated that electromagnetic radiation with a 935-MHz phone for 4 h conspicuously decreased mitochondrial membrane potential and lowered the calcium ion concentration of endometrial glandular cells. It is suggested that high-intensity electromagnetic radiation is very likely to induce the death of embryonic cells and decrease the chance of their implantation, thereby posing a high risk to pregnancy.

  6. RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells

    OpenAIRE

    Vasyutina, Elena; Lenhard, Diana C.; Wende, Hagen; Erdmann, Bettina; Epstein, Jonathan A.; Birchmeier, Carmen

    2007-01-01

    In the developing muscle, a pool of myogenic progenitor cells is formed and maintained. These resident progenitors provide a source of cells for muscle growth in development and generate satellite cells in the perinatal period. By the use of conditional mutagenesis in mice, we demonstrate here that the major mediator of Notch signaling, the transcription factor RBP-J, is essential to maintain this pool of progenitor cells in an undifferentiated state. In the absence of RBP-J, these cells unde...

  7. Smart Phones, a Powerful Tool in the Chemistry Classroom

    Science.gov (United States)

    Williams, Antony J.; Pence, Harry E.

    2011-01-01

    Cell phones, especially "smart phones", seem to have become ubiquitous. Actually, it is misleading to call many of these devices phones, as they are actually a portable and powerful computer that can be very valuable in the chemistry classroom. Currently, there are three major ways in which smart phones can be used for education. Smart phones…

  8. Smart Phones, a Powerful Tool in the Chemistry Classroom

    Science.gov (United States)

    Williams, Antony J.; Pence, Harry E.

    2011-01-01

    Cell phones, especially "smart phones", seem to have become ubiquitous. Actually, it is misleading to call many of these devices phones, as they are actually a portable and powerful computer that can be very valuable in the chemistry classroom. Currently, there are three major ways in which smart phones can be used for education. Smart phones…

  9. Efficacy of a randomized cell phone-based counseling intervention in postponing subsequent pregnancy among teen mothers.

    Science.gov (United States)

    Katz, Kathy S; Rodan, Margaret; Milligan, Renee; Tan, Sylvia; Courtney, Lauren; Gantz, Marie; Blake, Susan M; McClain, Lenora; Davis, Maurice; Kiely, Michele; Subramanian, Siva

    2011-12-01

    Adolescent mothers in Washington, DC have a high rate of subsequent teen pregnancies, often within 24 months. Children of teen mothers are at risk for adverse psychosocial outcomes. When adolescents are strongly attached to parents, schools, and positive peers, they may be less likely to repeat a pregnancy. This study tested the efficacy of a counseling intervention delivered by cell phone and focused on postponing subsequent teen pregnancies by strengthening healthy relationships, reproductive practices, and positive youth assets. The objective of this study was to compare time to a repeat pregnancy between the intervention and usual care groups, and, secondarily, to determine whether treatment intensity influenced time to subsequent conception. Primiparous pregnant teens ages 15-19, were recruited in Washington, DC. Of 849 teens screened, 29.3% (n = 249) met inclusion criteria, consented to participate, and completed baseline measures. They were then randomized to the intervention (N = 124) or to usual care (N = 125). Intervention group teens received cell phones for 18 months of counseling sessions, and quarterly group sessions. Follow-up measures assessed subsequent pregnancy through 24 months post-delivery. A survival analysis compared time to subsequent conception in the two treatment groups. Additional models examined the effect of treatment intensity. By 24 months, 31% of the intervention and 36% of usual care group teens had a subsequent pregnancy. Group differences were not statistically significant in intent-to-treat analysis. Because there was variability in the degree of exposure of teens to the curriculum, a survival analysis accounting for treatment intensity was performed and a significant interaction with age was detected. Participants who were aged 15-17 years at delivery showed a significant reduction in subsequent pregnancy with increased levels of intervention exposure (P < 0.01), but not those ≥ 18 years. Adolescents ≥ 18 years faced

  10. A role for RNA post-transcriptional regulation in satellite cell activation

    Directory of Open Access Journals (Sweden)

    Farina Nicholas H

    2012-10-01

    Full Text Available Abstract Background Satellite cells are resident skeletal muscle stem cells responsible for muscle maintenance and repair. In resting muscle, satellite cells are maintained in a quiescent state. Satellite cell activation induces the myogenic commitment factor, MyoD, and cell cycle entry to facilitate transition to a population of proliferating myoblasts that eventually exit the cycle and regenerate muscle tissue. The molecular mechanism involved in the transition of a quiescent satellite cell to a transit-amplifying myoblast is poorly understood. Methods Satellite cells isolated by FACS from uninjured skeletal muscle and 12 h post-muscle injury from wild type and Syndecan-4 null mice were probed using Affymetrix 430v2 gene chips and analyzed by Spotfiretm and Ingenuity Pathway analysis to identify gene expression changes and networks associated with satellite cell activation, respectively. Additional analyses of target genes identify miRNAs exhibiting dynamic changes in expression during satellite cell activation. The function of the miRNAs was assessed using miRIDIAN hairpin inhibitors. Results An unbiased gene expression screen identified over 4,000 genes differentially expressed in satellite cells in vivo within 12 h following muscle damage and more than 50% of these decrease dramatically. RNA binding proteins and genes involved in post-transcriptional regulation were significantly over-represented whereas splicing factors were preferentially downregulated and mRNA stability genes preferentially upregulated. Furthermore, six computationally identified miRNAs demonstrated novel expression through muscle regeneration and in satellite cells. Three of the six miRNAs were found to regulate satellite cell fate. Conclusions The quiescent satellite cell is actively maintained in a state poised to activate in response to external signals. Satellite cell activation appears to be regulated by post-transcriptional gene regulation.

  11. Semantic-Oriented Sentiment Classification for Chinese Product Reviews: An Experimental Study of Book and Cell Phone Reviews

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Sentiment classification is an automatic opinion classification method to classify the product reviews on web into positive or negative opinions to help consumers or sellers to understand the opinions and evaluations from existing customers. Semantic-oriented approach is one of the recent developments in sentiment classification. Up to now, most research of sentiment classification is on English reviews,and little work has been done on Chinese reviews using sentiment classification. The detailed techniques used in English review cannot be applied directly to Chinese reviews due to the different characteristics between these two languages. This study modified and improved the semantic-oriented approach to a 6-step process for Chinese review, focusing on the modification and improvement on the text segmentation and reference words pairs (RWPs) identification. Two experiments were conducted on book reviews and cell phone reviews. The results show that the performances of the proposed approach are comparable to those of the existing English reviews classification studies.

  12. The Effects of Internet Use, Cell Phones and Computer Games on Mental Health of Children and Adolescents

    Directory of Open Access Journals (Sweden)

    Meral Kelleci

    2008-06-01

    Full Text Available The use of digital technology, including computers, cell phones, computer games, and so on, most recently, on-the-go for recreational purposes, has increased among our youth over the past 15 years. Children and adolescent between the ages of 8 to 18 years spend an average of 5-6 hours per day using information and communication technologies. It is a useful progress because of the increase of internet usage which is unlimited, uncontrolled and uninhibited and easiness which arrival all sorts of to informations or persons but this state can cause to some important negative results too. The computer games, the internet explores is gradually estrange from social life the children and adolescent. In this paper, has been mentioned to negative effect of internet usage, computer games on mental health of children and adolescents. [TAF Prev Med Bull 2008; 7(3.000: 253-256

  13. On the Use of Cell Phones and Other Electronic Devices in the Classroom: Evidence from a Survey of Faculty and Students

    Science.gov (United States)

    Baker, William M.; Lusk, Edward J.; Neuhauser, Karyn L.

    2012-01-01

    The authors investigated faculty and student perceptions regarding the use of cell phones and other electronic devices in the classroom. Students differed markedly from faculty, with students exhibiting much greater acceptance of in-class use of technology. Among students, the authors found that gender affected perceptions. Specifically, male…

  14. Dr Math gets MUDDY: the "dirt" on how to attract teenagers to Mathematics and Science by using multi-user dungeon games over Mxit on cell phones

    CSIR Research Space (South Africa)

    Butgereit, L

    2010-05-01

    Full Text Available The current group of teenagers has been called many things – some of the terms unprintable in respectable publications. However terms such as the “thumb tribe” (because they can type faster on their cell phones with their thumbs than adults can type...

  15. Students' Use of Cell Phones in Class for Off-Task Behaviors: The Indirect Impact of Instructors' Teaching Behaviors through Boredom and Students' Attitudes

    Science.gov (United States)

    Bolkan, San; Griffin, Darrin J.

    2017-01-01

    This study was conducted to determine how various teaching behaviors influence students' emotional and cognitive experiences in class, and how these experiences relate to students' use of cell phones while considering contextual factors that might influence this outcome. Two hundred and seventy-four students responded to questions regarding their…

  16. Weight loss intervention for young adults using mobile technology: design and rationale of a randomized controlled trial – Cell phone Intervention for You (CITY)

    Science.gov (United States)

    Batch, Bryan C.; Tyson, Crystal; Bagwell, Jacqueline; Corsino, Leonor; Intille, Stephen; Lin, Pao-Hwa; Lazenka, Tony; Bennett, Gary; Bosworth, Hayden B.; Voils, Corrine; Grambow, Steven; Sutton, Aziza; Bordogna, Rachel; Pangborn, Matthew; Schwager, Jenifer; Pilewski, Kate; Caccia, Carla; Burroughs, Jasmine; Svetkey, Laura P.

    2014-01-01

    Background The obesity epidemic has spread to young adults, leading to significant public health implications later in adulthood. Intervention in early adulthood may be an effective public health strategy for reducing the long-term health impact of the epidemic. Few weight loss trials have been conducted in young adults. It is unclear what weight loss strategies are beneficial in this population. Purpose To describe the design and rationale of the NHLBI-sponsored Cell Phone Intervention for You (CITY) study, which is a single center, randomized three-arm trial that compares the impact on weight loss of 1) a behavioral intervention that is delivered almost entirely via cell phone technology (Cell Phone group); and 2) a behavioral intervention delivered mainly through monthly personal coaching calls enhanced by self-monitoring via cell phone (Personal Coaching group), each compared to; 3) a usual care, advice-only control condition. Methods A total of 365 community-dwelling overweight/obese adults aged 18–35 years were randomized to receive one of these three interventions for 24 months in parallel group design. Study personnel assessing outcomes were blinded to group assignment. The primary outcome is weight change at 12 months. We hypothesize that each active intervention will cause more weight loss than the usual care condition. Study completion is anticipated in 2014. Conclusions If effective, implementation of the CITY interventions could mitigate the alarming rates of obesity in young adults through promotion of weight loss. PMID:24462568

  17. Feasibility and Perceptions of Cell Phone-Based, Health-Related Communication With Adolescents in an Economically Depressed Area.

    Science.gov (United States)

    Sawni, Anju; Cederna-Meko, Crystal; LaChance, Jenny L; Buttigieg, Angie; Le, Quoc; Nunuk, Irene; Ang, Joyce; Burrell, Katherine M

    2017-02-01

    We examined the feasibility and perception of cell-based (texting, voicemail [VM], and email/social media), health-related communication with adolescents in Genesee County, MI, where 22% reside below the poverty level. Results of an anonymous survey found that 86% of respondents owned a cell phone, 87% had data, 96% texted, 90.5% emailed/used social media, and 68% had VM. Most adolescents were interested in cell-based communication via texting (52%), VM (37%), and email/social media (31%). Interest in types of health communication included appointment reminders (99% texting; 94% VM; 95% email/social media), shot reminders (84.5% texting; 74.5% VM; 81% email/social media), call for test results (71.5% texting; 75% VM; 65% email/social media), medication reminders (63% texting; 54% VM; 58% e-mail/social media), and health tips (36% texting; 18.5% VM; 73% email/social media). Cell-based health-related communication with adolescents is feasible even within low socioeconomic status populations, primarily via texting. Health providers should embrace cell-based patient communication.

  18. Impaired energy metabolism of senescent muscle satellite cells is associated with oxidative modifications of glycolytic enzymes

    DEFF Research Database (Denmark)

    Baraibar, Martín A; Hyzewicz, Janek; Rogowska-Wrzesinska, Adelina

    2016-01-01

    Accumulation of oxidized proteins is a hallmark of cellular and organismal aging. Adult muscle stem cell (or satellite cell) replication and differentiation is compromised with age contributing to sarcopenia. However, the molecular events related to satellite cell dysfunction during aging are not...

  19. Discovery of Novel Small Molecules that Activate Satellite Cell Proliferation and Enhance Repair of Damaged Muscle.

    Science.gov (United States)

    Billin, Andrew N; Bantscheff, Marcus; Drewes, Gerard; Ghidelli-Disse, Sonja; Holt, Jason A; Kramer, Henning F; McDougal, Alan J; Smalley, Terry L; Wells, Carrow I; Zuercher, William J; Henke, Brad R

    2016-02-19

    Skeletal muscle progenitor stem cells (referred to as satellite cells) represent the primary pool of stem cells in adult skeletal muscle responsible for the generation of new skeletal muscle in response to injury. Satellite cells derived from aged muscle display a significant reduction in regenerative capacity to form functional muscle. This decrease in functional recovery has been attributed to a decrease in proliferative capacity of satellite cells. Hence, agents that enhance the proliferative abilities of satellite cells may hold promise as therapies for a variety of pathological settings, including repair of injured muscle and age- or disease-associated muscle wasting. Through phenotypic screening of isolated murine satellite cells, we identified a series of 2,4-diaminopyrimidines (e.g., 2) that increased satellite cell proliferation. Importantly, compound 2 was effective in accelerating repair of damaged skeletal muscle in an in vivo mouse model of skeletal muscle injury. While these compounds were originally prepared as c-Jun N-terminal kinase 1 (JNK-1) inhibitors, structure-activity analyses indicated JNK-1 inhibition does not correlate with satellite cell activity. Screening against a broad panel of kinases did not result in identification of an obvious molecular target, so we conducted cell-based proteomics experiments in an attempt to identify the molecular target(s) responsible for the potentiation of the satellite cell proliferation. These data provide the foundation for future efforts to design improved small molecules as potential therapeutics for muscle repair and regeneration.

  20. Rb1 gene inactivation expands satellite cell and postnatal myoblast pools.

    Science.gov (United States)

    Hosoyama, Tohru; Nishijo, Koichi; Prajapati, Suresh I; Li, Guangheng; Keller, Charles

    2011-06-03

    Satellite cells are well known as a postnatal skeletal muscle stem cell reservoir that under injury conditions participate in repair. However, mechanisms controlling satellite cell quiescence and activation are the topic of ongoing inquiry by many laboratories. In this study, we investigated whether loss of the cell cycle regulatory factor, pRb, is associated with the re-entry of quiescent satellite cells into replication and subsequent stem cell expansion. By ablation of Rb1 using a Pax7CreER,Rb1 conditional mouse line, satellite cell number was increased 5-fold over 6 months. Furthermore, myoblasts originating from satellite cells lacking Rb1 were also increased 3-fold over 6 months, while terminal differentiation was greatly diminished. Similarly, Pax7CreER,Rb1 mice exhibited muscle fiber hypotrophy in vivo under steady state conditions as well as a delay of muscle regeneration following cardiotoxin-mediated injury. These results suggest that cell cycle re-entry of quiescent satellite cells is accelerated by lack of Rb1, resulting in the expansion of both satellite cells and their progeny in adolescent muscle. Conversely, that sustained Rb1 loss in the satellite cell lineage causes a deficit of muscle fiber formation. However, we also show that pharmacological inhibition of protein phosphatase 1 activity, which will result in pRb inactivation accelerates satellite cell activation and/or expansion in a transient manner. Together, our results raise the possibility that reversible pRb inactivation in satellite cells and inhibition of protein phosphorylation may provide a new therapeutic tool for muscle atrophy by short term expansion of the muscle stem cells and myoblast pool.

  1. High acceptability for cell phone text messages to improve communication of laboratory results with HIV-infected patients in rural Uganda: a cross-sectional survey study

    Directory of Open Access Journals (Sweden)

    Siedner Mark J

    2012-06-01

    Full Text Available Abstract Background Patient-provider communication is a major challenge in resource-limited settings with large catchment areas. Though mobile phone usership increased 20-fold in Africa over the past decade, little is known about acceptability of, perceptions about disclosure and confidentiality, and preferences for cell phone communication of health information in the region. Methods We performed structured interviews of fifty patients at the Immune Suppression Syndrome clinic in Mbarara, Uganda to assess four domains of health-related communication: a cell phone use practices and literacy, b preferences for laboratory results communication, c privacy and confidentiality, and d acceptability of and preferences for text messaging to notify patients of abnormal test results. Results Participants had a median of 38 years, were 56% female, and were residents of a large catchment area throughout southwestern Uganda. All participants expressed interest in a service to receive information about laboratory results by cell phone text message, stating benefits of increased awareness of their health and decreased transportation costs. Ninety percent reported that they would not be concerned for unintended disclosure. A minority additionally expressed concerns about difficulty interpreting messages, discouragement upon learning bad news, and technical issues. Though all respondents expressed interest in password protection of messages, there was also a strong desire for direct messages to limit misinterpretation of information. Conclusions Cell phone text messaging for communication of abnormal laboratory results is highly acceptable in this cohort of HIV-infected patients in rural Uganda. The feasibility of text messaging, including an optimal balance between privacy and comprehension, should be further studied.

  2. Isolation, culture and biological characteristics of multipotent porcine skeletal muscle satellite cells.

    Science.gov (United States)

    Yang, Jinjuan; Liu, Hao; Wang, Kunfu; Li, Lu; Yuan, Hongyi; Liu, Xueting; Liu, Yingjie; Guan, Weijun

    2017-03-02

    Skeletal muscle has a huge regenerative potential for postnatal muscle growth and repair, which mainly depends on a kind of muscle progenitor cell population, called satellite cell. Nowadays, the majority of satellite cells were obtained from human, mouse, rat and other animals but rarely from pig. In this article, the porcine skeletal muscle satellite cells were isolated and cultured in vitro. The expression of surface markers of satellite cells was detected by immunofluorescence and RT-PCR assays. The differentiation capacity was assessed by inducing satellite cells into adipocytes, myoblasts and osteoblasts. The results showed that satellite cells isolated from porcine tibialis anterior were subcultured up to 12 passages and were positive for Pax7, Myod, c-Met, desmin, PCNA and NANOG but were negative for Myogenin. Satellite cells were also induced to differentiate into adipocytes, osteoblasts and myoblasts, respectively. These findings indicated that porcine satellite cells possess similar biological characteristics of stem cells, which may provide theoretical basis and experimental evidence for potential therapeutic application in the treatment of dystrophic muscle and other muscle injuries.

  3. Satellite Cells Contribution to Exercise Mediated Muscle Hypertrophy and Repair

    Science.gov (United States)

    Bazgir, Behzad; Fathi, Rouhollah; Rezazadeh Valojerdi, Mojtaba; Mozdziak, Paul; Asgari, Alireza

    2017-01-01

    Satellite cells (SCs) are the most abundant skeletal muscle stem cells. They are widely recognized for their contributions to maintenance of muscle mass, regeneration and hypertrophy during the human life span. These cells are good candidates for cell therapy due to their self-renewal capabilities and presence in an undifferentiated form. Presently, a significant gap exists between our knowledge of SCs behavior and their application as a means for human skeletal muscle tissue repair and regeneration. Both physiological and pathological stimuli potentially affect SCs activation, proliferation, and terminal differentiation the former category being the focus of this article. Activation of SCs occurs following exercise, post-training micro-injuries, and electrical stimulation. Exercise, as a potent and natural stimulus, is at the center of numerous studies on SC activation and relevant fields. According to research, different exercise modalities end with various effects. This review article attempts to picture the state of the art of the SCs life span and their engagement in muscle regeneration and hypertrophy in exercise. PMID:28042532

  4. Satellite Cells Contribution to Exercise Mediated Muscle Hypertrophy and Repair

    Directory of Open Access Journals (Sweden)

    Behzad Bazgir

    2016-10-01

    Full Text Available Satellite cells (SCs are the most abundant skeletal muscle stem cells. They are widely recognized for their contributions to maintenance of muscle mass, regeneration and hypertrophy during the human life span. These cells are good candidates for cell therapy due to their self-renewal capabilities and presence in an undifferentiated form. Presently, a significant gap exists between our knowledge of SCs behavior and their application as a means for human skeletal muscle tissue repair and regeneration. Both physiological and pathological stimuli potentially affect SCs activation, proliferation, and terminal differentiation - the former category being the focus of this article. Activation of SCs occurs following exercise, post-training micro-injuries, and electrical stimulation. Exercise, as a potent and natural stimulus, is at the center of numerous studies on SC activation and relevant fields. According to research, different exercise modalities end with various effects. This review article attempts to picture the state of the art of the SCs life span and their engagement in muscle regeneration and hypertrophy in exercise.

  5. Globular adiponectin activates motility and regenerative traits of muscle satellite cells.

    Directory of Open Access Journals (Sweden)

    Tania Fiaschi

    Full Text Available Regeneration of adult injured skeletal muscle is due to activation of satellite cells, a population of stem cells resident beneath the basal lamina. Thus, information on soluble factors affecting satellite cell activation, as well as migration towards injury and fusion into new myofibers are essential. Here, we show that globular adiponectin (gAd, positively affects several features of muscle satellite cells. gAd activates satellite cells to exit quiescence and increases their recruitment towards myotubes. gAd elicits in satellite cells a specific motility program, involving activation of the small GTPase Rac1, as well as expression of Snail and Twist transcription factors driving a proteolytic motility, useful to reach the site of injury. We show that satellite cells produce autocrine full length adiponectin (fAd, which is converted to gAd by activated macrophages. In turns, gAd concurs to attract to the site of injury both satellite cells and macrophages and induces myogenesis in muscle satellite cells. Thus, these findings add a further role for gAd in skeletal muscle, including the hormone among factors participating in muscle regeneration.

  6. Differential satellite cell density of type I and II fibres with lifelong endurance running in old men

    DEFF Research Database (Denmark)

    Mackey, Abigail; Karlsen, A; Couppé, C

    2014-01-01

    between these variables were determined. RESULTS: In O-Un and O-Tr, type II fibres were smaller and contained fewer satellite cells than type I fibres. However, when expressed relative to fibre area, the difference in satellite cell content between fibre types was eliminated in O-Tr, but not O...... the satellite cell pool and (ii) is associated with a similar density of satellite cells in type I and II fibres despite a failure to preserve the equal fibre type distribution of satellite cells observed in young individuals. Taken together, these data reveal a differential regulation of satellite cell content...

  7. Sox2 promotes survival of satellite glial cells in vitro

    Energy Technology Data Exchange (ETDEWEB)

    Koike, Taro, E-mail: koiket@hirakata.kmu.ac.jp; Wakabayashi, Taketoshi; Mori, Tetsuji; Hirahara, Yukie; Yamada, Hisao

    2015-08-14

    Sox2 is a transcriptional factor expressed in neural stem cells. It is known that Sox2 regulates cell differentiation, proliferation and survival of the neural stem cells. Our previous study showed that Sox2 is expressed in all satellite glial cells of the adult rat dorsal root ganglion. In this study, to examine the role of Sox2 in satellite glial cells, we establish a satellite glial cell-enriched culture system. Our culture method succeeded in harvesting satellite glial cells with the somata of neurons in the dorsal root ganglion. Using this culture system, Sox2 was downregulated by siRNA against Sox2. The knockdown of Sox2 downregulated ErbB2 and ErbB3 mRNA at 2 and 4 days after siRNA treatment. MAPK phosphorylation, downstream of ErbB, was also inhibited by Sox2 knockdown. Because ErbB2 and ErbB3 are receptors that support the survival of glial cells in the peripheral nervous system, apoptotic cells were also counted. TUNEL-positive cells increased at 5 days after siRNA treatment. These results suggest that Sox2 promotes satellite glial cell survival through the MAPK pathway via ErbB receptors. - Highlights: • We established satellite glial cell culture system. • Function of Sox2 in satellite glial cell was examined using siRNA. • Sox2 knockdown downregulated expression level of ErbB2 and ErbB3 mRNA. • Sox2 knockdown increased apoptotic satellite glial cell. • Sox2 promotes satellite glial cell survival through ErbB signaling.

  8. Assessment of satellite cell number and activity status in human skeletal muscle biopsies

    DEFF Research Database (Denmark)

    Mackey, Abigail; Kjaer, Michael; Charifi, Nadia;

    2009-01-01

    The primary aim of our study was to validate the assessment of myonuclear and satellite cell number in biopsies from human skeletal muscle. We found that 25 type I and 25 type II fibers are sufficient to estimate the mean number of myonuclei per fiber. In contrast, the assessment of satellite cells...

  9. Isolation and characterization of satellite cells from rat head branchiomeric muscles

    NARCIS (Netherlands)

    Carvajal Monroy, P.L.; Yablonka-Reuveni, Z.; Grefte, Sander; Kuijpers-Jagtman, Anne Marie; Wagener, F.A.D.T.G.; Hoff, Von den J.W.

    2015-01-01

    This protocol describes the isolation of satellite cells from branchiomeric head muscles of a 9 week-old rat. The muscles originate from different branchial arches. Subsequently, the satellite cells are cultured on a spot coating of millimeter size to study their differentiation. This approach avoid

  10. A myogenic precursor cell that could contribute to regeneration in zebrafish and its similarity to the satellite cell.

    Science.gov (United States)

    Siegel, Ashley L; Gurevich, David B; Currie, Peter D

    2013-09-01

    The cellular basis for mammalian muscle regeneration has been an area of intense investigation over recent decades. The consensus is that a specialized self-renewing stem cell, termed the satellite cell, plays a major role during the process of regeneration in amniotes. How broadly this mechanism is deployed within the vertebrate phylogeny remains an open question. A lack of information on the role of cells analogous to the satellite cell in other vertebrate systems is even more unexpected given the fact that satellite cells were first designated in frogs. An intriguing aspect of this debate is that a number of amphibia and many fish species exhibit epimorphic regenerative processes in specific tissues, whereby regeneration occurs by the dedifferentiation of the damaged tissue, without deploying specialized stem cell populations analogous to satellite cells. Hence, it is feasible that a cellular process completely distinct from that deployed during mammalian muscle regeneration could operate in species capable of epimorphic regeneration. In this minireview, we examine the evidence for the broad phylogenetic distribution of satellite cells. We conclude that, in the vertebrates examined so far, epimorphosis does not appear to be deployed during muscle regeneration, and that analogous cells expressing similar marker genes to satellite cells appear to be deployed during the regenerative process. However, the functional definition of these cells as self-renewing muscle stem cells remains a final hurdle to the definition of the satellite cell as a generic vertebrate cell type.

  11. Notch Signaling Rescues Loss of Satellite Cells Lacking Pax7 and Promotes Brown Adipogenic Differentiation.

    Science.gov (United States)

    Pasut, Alessandra; Chang, Natasha C; Rodriguez, Uxia Gurriaran; Faulkes, Sharlene; Yin, Hang; Lacaria, Melanie; Ming, Hong; Rudnicki, Michael A

    2016-07-12

    Pax7 is a nodal transcription factor that is essential for regulating the maintenance, expansion, and myogenic identity of satellite cells during both neonatal and adult myogenesis. Deletion of Pax7 results in loss of satellite cells and impaired muscle regeneration. Here, we show that ectopic expression of the constitutively active intracellular domain of Notch1 (NICD1) rescues the loss of Pax7-deficient satellite cells and restores their proliferative potential. Strikingly NICD1-expressing satellite cells do not undergo myogenic differentiation and instead acquire a brown adipogenic fate both in vivo and in vitro. NICD-expressing Pax7(-/-) satellite cells fail to upregulate MyoD and instead express the brown adipogenic marker PRDM16. Overall, these results show that Notch1 activation compensates for the loss of Pax7 in the quiescent state and acts as a molecular switch to promote brown adipogenesis in adult skeletal muscle.

  12. Effects of cell phone radiation on lipid peroxidation, glutathione and nitric oxide levels in mouse brain during epileptic seizure.

    Science.gov (United States)

    Esmekaya, Meric Arda; Tuysuz, Mehmet Zahid; Tomruk, Arın; Canseven, Ayse G; Yücel, Engin; Aktuna, Zuhal; Keskil, Semih; Seyhan, Nesrin

    2016-09-01

    The objective of the this study was to evaluate the effects of cellular phone radiation on oxidative stress parameters and oxide levels in mouse brain during pentylenetetrazole (PTZ) induced epileptic seizure. Eight weeks old mice were used in the study. Animals were distributed in the following groups: Group I: Control group treated with PTZ, Group II: 15min cellular phone radiation+PTZ treatment+30min cellular phone radiation, Group III: 30min cellular phone radiation+PTZ treatment+30min cellular phone radiation. The RF radiation was produced by a 900MHz cellular phone. Lipid peroxidation, which is the indicator of oxidative stress was quantified by measuring the formation of thiobarbituric acid reactive substances (TBARS). The glutathione (GSH) levels were determined by the Ellman method. Tissue total nitric oxide (NOx) levels were obtained using the Griess assay. Lipid peroxidation and NOx levels of brain tissue increased significantly in group II and III compared to group I. On the contrary, GSH levels were significantly lower in group II and III than group I. However, no statistically significant alterations in any of the endpoints were noted between group II and Group III. Overall, the experimental findings demonstrated that cellular phone radiation may increase the oxidative damage and NOx level during epileptic activity in mouse brain.

  13. Methods for Observing and Quantifying Muscle Satellite Cell Motility and Invasion In Vitro.

    Science.gov (United States)

    Lund, Dane K; McAnulty, Patrick; Siegel, Ashley L; Cornelison, Ddw

    2017-01-01

    Motility and/or chemotaxis of satellite cells has been suggested or observed in multiple in vitro and in vivo contexts. Satellite cell motility also affects the efficiency of muscle regeneration, particularly in the context of engrafted exogenous cells. Consequently, there is keen interest in determining what cell-autonomous and environmental factors influence satellite cell motility and chemotaxis in vitro and in vivo. In addition, the ability of activated satellite cells to relocate in vivo would suggest that they must be able to invade and transit through the extracellular matrix (ECM), which is supported by studies in which alteration or addition of matrix metalloprotease (MMP) activity enhanced the spread of engrafted satellite cells. However, despite its potential importance, analysis of satellite cell motility or invasion quantitatively even in an in vitro setting can be difficult; one of the most powerful techniques for overcoming these difficulties is timelapse microscopy. Identification and longitudinal evaluation of individual cells over time permits not only quantification of variations in motility due to intrinsic or extrinsic factors, it permits observation and analysis of other (frequently unsuspected) cellular activities as well. We describe here three protocols developed in our group for quantitatively analyzing satellite cell motility over time in two dimensions on purified ECM substrates, in three dimensions on a living myofiber, and in three dimensions through an artificial matrix.

  14. Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population.

    Science.gov (United States)

    Morrison, Jamie I; Lööf, Sara; He, Pingping; Simon, András

    2006-01-30

    In contrast to mammals, salamanders can regenerate complex structures after injury, including entire limbs. A central question is whether the generation of progenitor cells during limb regeneration and mammalian tissue repair occur via separate or overlapping mechanisms. Limb regeneration depends on the formation of a blastema, from which the new appendage develops. Dedifferentiation of stump tissues, such as skeletal muscle, precedes blastema formation, but it was not known whether dedifferentiation involves stem cell activation. We describe a multipotent Pax7+ satellite cell population located within the skeletal muscle of the salamander limb. We demonstrate that skeletal muscle dedifferentiation involves satellite cell activation and that these cells can contribute to new limb tissues. Activation of salamander satellite cells occurs in an analogous manner to how the mammalian myofiber mobilizes stem cells during skeletal muscle tissue repair. Thus, limb regeneration and mammalian tissue repair share common cellular and molecular programs. Our findings also identify satellite cells as potential targets in promoting mammalian blastema formation.

  15. Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import.

    Science.gov (United States)

    Choo, Hyo-Jung; Cutler, Alicia; Pavlath, Grace K

    2016-07-19

    Satellite cells are stem cells with an essential role in skeletal muscle repair. Precise regulation of gene expression is critical for proper satellite cell quiescence, proliferation, differentiation and self-renewal. Nuclear proteins required for gene expression are dependent on the nucleocytoplasmic transport machinery to access to nucleus, however little is known about regulation of nuclear transport in satellite cells. The best characterized nuclear import pathway is classical nuclear import which depends on a classical nuclear localization signal (cNLS) in a cargo protein and the heterodimeric import receptors, karyopherin alpha (KPNA) and beta (KPNB). Multiple KPNA1 paralogs exist and can differ in importing specific cNLS proteins required for cell differentiation and function. We show that transcripts for six Kpna paralogs underwent distinct changes in mouse satellite cells during muscle regeneration accompanied by changes in cNLS proteins in nuclei. Depletion of KPNA1, the most dramatically altered KPNA, caused satellite cells in uninjured muscle to prematurely activate, proliferate and undergo apoptosis leading to satellite cell exhaustion with age. Increased proliferation of satellite cells led to enhanced muscle regeneration at early stages of regeneration. In addition, we observed impaired nuclear localization of two key KPNA1 cargo proteins: p27, a cyclin-dependent kinase inhibitor associated with cell cycle control and lymphoid enhancer factor 1, a critical cotranscription factor for β-catenin. These results indicate that regulated nuclear import of proteins by KPNA1 is critical for satellite cell proliferation and survival and establish classical nuclear import as a novel regulatory mechanism for controlling satellite cell fate. Stem Cells 2016.

  16. Satellite-like cells contribute to pax7-dependent skeletal muscle repair in adult zebrafish.

    Science.gov (United States)

    Berberoglu, Michael A; Gallagher, Thomas L; Morrow, Zachary T; Talbot, Jared C; Hromowyk, Kimberly J; Tenente, Inês M; Langenau, David M; Amacher, Sharon L

    2017-04-15

    Satellite cells, also known as muscle stem cells, are responsible for skeletal muscle growth and repair in mammals. Pax7 and Pax3 transcription factors are established satellite cell markers required for muscle development and regeneration, and there is great interest in identifying additional factors that regulate satellite cell proliferation, differentiation, and/or skeletal muscle regeneration. Due to the powerful regenerative capacity of many zebrafish tissues, even in adults, we are exploring the regenerative potential of adult zebrafish skeletal muscle. Here, we show that adult zebrafish skeletal muscle contains cells similar to mammalian satellite cells. Adult zebrafish satellite-like cells have dense heterochromatin, express Pax7 and Pax3, proliferate in response to injury, and show peak myogenic responses 4-5 days post-injury (dpi). Furthermore, using a pax7a-driven GFP reporter, we present evidence implicating satellite-like cells as a possible source of new muscle. In lieu of central nucleation, which distinguishes regenerating myofibers in mammals, we describe several characteristics that robustly identify newly-forming myofibers from surrounding fibers in injured adult zebrafish muscle. These characteristics include partially overlapping expression in satellite-like cells and regenerating myofibers of two RNA-binding proteins Rbfox2 and Rbfoxl1, known to regulate embryonic muscle development and function. Finally, by analyzing pax7a; pax7b double mutant zebrafish, we show that Pax7 is required for adult skeletal muscle repair, as it is in the mouse.

  17. Comparison and analysis of Wuding and avian chicken skeletal muscle satellite cells.

    Science.gov (United States)

    Tong, H Q; Jiang, Z Q; Dou, T F; Li, Q H; Xu, Z Q; Liu, L X; Gu, D H; Rong, H; Huang, Y; Chen, X B; Jois, M; Te Pas, M F W; Ge, C R; Jia, J J

    2016-10-05

    Chicken skeletal muscle satellite cells are located between the basement membrane and the sarcolemma of mature muscle fibers. Avian broilers have been genetically selected based on their high growth velocity and large muscle mass. The Wuding chicken is a famous local chicken in Yunnan Province that undergoes non-selection breeding and is slow growing. In this study, we aimed to explore differences in the proliferation and differentiation properties of satellite cells isolated from the two chicken breeds. Using immunofluorescence, hematoxylin-eosin staining and real-time polymerase chain reaction analysis, we analyzed the in vitro characteristics of proliferating and differentiating satellite cells isolated from the two chicken breeds. The growth curve of satellite cells was S-shaped, and cells from Wuding chickens entered the logarithmic phase and plateau phase 1 day later than those from Avian chicken. The results also showed that the two skeletal muscle satellite cell lines were positive for Pax7, MyoD and IGF-1. The expression of Pax7 followed a downward trend, whereas that of MyoD and IGF-1 first increased and subsequently decreased in cells isolated from the two chickens. These data indicated that the skeletal muscle satellite cells of Avian chicken grow and differentiate faster than did those of Wuding chickens. We suggest that the methods of breeding selection applied to these breeds regulate the characteristics of skeletal muscle satellite cells to influence muscle growth.

  18. Phenotypic changes in satellite glial cells in cultured trigeminal ganglia.

    Science.gov (United States)

    Belzer, Vitali; Shraer, Nathanael; Hanani, Menachem

    2010-11-01

    Satellite glial cells (SGCs) are specialized cells that form a tight sheath around neurons in sensory ganglia. In recent years, there is increasing interest in SGCs and they have been studied in both intact ganglia and in tissue culture. Here we studied phenotypic changes in SGCs in cultured trigeminal ganglia from adult mice, containing both neurons and SGCs, using phase optics, immunohistochemistry and time-lapse photography. Cultures were followed for up to 14 days. After isolation virtually every sensory neuron is ensheathed by SGCs, as in the intact ganglia. After one day in culture, SGCs begin to migrate away from their parent neurons, but in most cases the neurons still retain an intact glial cover. At later times in culture, there is a massive migration of SGCs away from the neurons and they undergo clear morphological changes, and at 7 days they become spindle-shaped. At one day in culture SGCs express the glial marker glutamine synthetase, and also the purinergic receptor P2X7. From day 2 in culture the glutamine synthetase expression is greatly diminished, whereas that of P2X7 is largely unchanged. We conclude that SGCs retain most of their characteristics for about 24 h after culturing, but undergo major phenotypic changes at later times.

  19. Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin.

    Science.gov (United States)

    Guardiola, Ombretta; Lafuste, Peggy; Brunelli, Silvia; Iaconis, Salvatore; Touvier, Thierry; Mourikis, Philippos; De Bock, Katrien; Lonardo, Enza; Andolfi, Gennaro; Bouché, Ann; Liguori, Giovanna L; Shen, Michael M; Tajbakhsh, Shahragim; Cossu, Giulio; Carmeliet, Peter; Minchiotti, Gabriella

    2012-11-20

    Skeletal muscle regeneration mainly depends on satellite cells, a population of resident muscle stem cells. However, our understanding of the molecular mechanisms underlying satellite cell activation is still largely undefined. Here, we show that Cripto, a regulator of early embryogenesis, is a novel regulator of muscle regeneration and satellite cell progression toward the myogenic lineage. Conditional inactivation of cripto in adult satellite cells compromises skeletal muscle regeneration, whereas gain of function of Cripto accelerates regeneration, leading to muscle hypertrophy. Moreover, we provide evidence that Cripto modulates myogenic cell determination and promotes proliferation by antagonizing the TGF-β ligand myostatin. Our data provide unique insights into the molecular and cellular basis of Cripto activity in skeletal muscle regeneration and raise previously undescribed implications for stem cell biology and regenerative medicine.

  20. Cellular Phone Towers, Cell Towers, Published in 2008, 1:2400 (1in=200ft) scale, Hamilton County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Not Provided information as of 2008. It is described as...

  1. Cellular Phone Towers, Cell Sectors, Published in 2008, 1:2400 (1in=200ft) scale, Hamilton County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Not Provided information as of 2008. It is described as...

  2. Cellular Phone Towers, Cell Towers, Published in 2007, 1:1200 (1in=100ft) scale, Ness County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:1200 (1in=100ft) scale, was produced all or in part from Orthoimagery information as of 2007. It is described as...

  3. Cellular Phone Towers, Cell Towers, Published in 2010, 1:1200 (1in=100ft) scale, Liberty County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:1200 (1in=100ft) scale, was produced all or in part from Orthoimagery information as of 2010. It is described as...

  4. Cellular Phone Towers, cell sectors, Published in 2008, 1:2400 (1in=200ft) scale, Stanton County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Not Provided information as of 2008. It is described as...

  5. Cellular Phone Towers, Cell Towers, Published in 2010, 1:1200 (1in=100ft) scale, Douglas County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:1200 (1in=100ft) scale, was produced all or in part from Published Reports/Deeds information as of 2010. It is...

  6. Cellular Phone Towers, Cell Towers, Published in 2007, 1:4800 (1in=400ft) scale, Harvey County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:4800 (1in=400ft) scale, was produced all or in part from Orthoimagery information as of 2007. It is described as...

  7. The effect of temperature on proliferation and differentiation of chicken skeletal muscle satellite cells isolated from different muscle types.

    Science.gov (United States)

    Harding, Rachel L; Halevy, Orna; Yahav, Shlomo; Velleman, Sandra G

    2016-04-01

    Skeletal muscle satellite cells are a muscle stem cell population that mediate posthatch muscle growth and repair. Satellite cells respond differentially to environmental stimuli based upon their fiber-type of origin. The objective of this study was to determine how temperatures below and above the in vitro control of 38°C affected the proliferation and differentiation of satellite cells isolated from the chicken anaerobic pectoralis major (p. major) or mixed fiber biceps femoris (b.femoris) muscles. The satellite cells isolated from the p. major muscle were more sensitive to both cold and hot temperatures compared to the b.femoris satellite cells during both proliferation and differentiation. The expressions of myogenic regulatory transcription factors were also different between satellite cells from different fiber types. MyoD expression, which partially regulates proliferation, was generally expressed at higher levels in p. major satellite cells compared to the b.femoris satellite cells from 33 to 43°C during proliferation and differentiation. Similarly, myogenin expression, which is required for differentiation, was also expressed at higher levels in p. major satellite cells in response to both cold and hot temperatures during proliferation and differentiation than b. femoris satellite cells. These data demonstrate that satellite cells from the anaerobic p. major muscle are more sensitive than satellite cells from the aerobic b. femoris muscle to both hot and cold thermal stress during myogenic proliferation and differentiation.

  8. A Two-Stage Taguchi Design ExampleImage Quality Promotion in Miniature Camera/Cell-Phone Lens

    Directory of Open Access Journals (Sweden)

    Luke K. Wang

    2012-07-01

    Full Text Available A simple, practical manufacturing process, integrating manufacturing capability-oriented design (MCOD philosophy and Taguchi’s method, is presented to tackle the high resolution miniature camera/cell phone lens issues at the manufacturing phase. Meanwhile, we also use optical software to create an analytical simulation model to investigate the quality characteristics due to lens’ thickness, eccentricity, surface profile, and air lens’ gap; a single quality characteristics expressed in terms of modulation transfer function (MTF is defined. Optimal combination of process parameters in experimental scenario using Taguchi’s method is performed, and the results are judged and analyzed by the indices of signal-to-noise ratio (S/N and the analysis of variance (ANOVA. The key idea of the two-stage design is to utilize optical software to conduct the sensitivity analysis of MTF first; an analytical model, dependent on actual process parameters at manufacturing stage, is constructed next; and finally by substituting these outputs from the analytical model back to the optical software to verify the design criterion and do the modifications. By minimizing both the theoretical errors at design stage and the complexity in the manufacturing process, we are able to seeking for the most economical solution, simultaneously attain the optimal/suboptimal combination of process parameters or control factors in lens manufacturing issue.

  9. Image and diagnosis quality of X-ray image transmission via cell phone camera: a project study evaluating quality and reliability.

    Directory of Open Access Journals (Sweden)

    Hans Goost

    Full Text Available INTRODUCTION: Developments in telemedicine have not produced any relevant benefits for orthopedics and trauma surgery to date. For the present project study, several parameters were examined during assessment of x-ray images, which had been photographed and transmitted via cell phone. MATERIALS AND METHODS: A total of 100 x-ray images of various body regions were photographed with a Nokia cell phone and transmitted via email or MMS. Next, the transmitted photographs were reviewed on a laptop computer by five medical specialists and assessed regarding quality and diagnosis. RESULTS: Due to their poor quality, the transmitted MMS images could not be evaluated and this path of transmission was therefore excluded. Mean size of transmitted x-ray email images was 394 kB (range: 265-590 kB, SD ± 59, average transmission time was 3.29 min ± 8 (CI 95%: 1.7-4.9. Applying a score from 1-10 (very poor - excellent, mean image quality was 5.8. In 83.2 ± 4% (mean value ± SD of cases (median 82; 80-89%, there was agreement between final diagnosis and assessment by the five medical experts who had received the images. However, there was a markedly low concurrence ratio in the thoracic area and in pediatric injuries. DISCUSSION: While the rate of accurate diagnosis and indication for surgery was high with a concurrence ratio of 83%, considerable differences existed between the assessed regions, with lowest values for thoracic images. Teleradiology is a cost-effective, rapid method which can be applied wherever wireless cell phone reception is available. In our opinion, this method is in principle suitable for clinical use, enabling the physician on duty to agree on appropriate measures with colleagues located elsewhere via x-ray image transmission on a cell phone.

  10. 手机健康管理软件在门诊患者中的应用%Application of Cell Phone Health Management Software in Outpatients

    Institute of Scientific and Technical Information of China (English)

    赵明红; 尚旭丽; 包玉美

    2015-01-01

    目的探讨手机健康管理软件在门诊患者健康管理中的应用效果。方法随机抽取146名门诊患者使用手机下载健康管理软件,随访后观察健康管理效果,与使用前情况进行比较。结果使用手机健康管理软件后,能明显提高患者疾病知识掌握程度、治疗依从性;预约率、患者满意度等,与使用前比较差异有统计学意义(P<0.01)。结论将手机健康管理软件应用于门诊患者,对患者健康管理有积极作用,值得临床推广应用。%Objective To discuss the application effects of cell phone health management software in outpatients' health management.Methods 146 outpatients were randomly selected to use cell phone health management software. Observed health management effects after follow-up visits and compared it with before.Results After using cell phone health management software, patients' knowledge of disease, treatment compliance, reservation rate, patient satisfaction were significantly improve with statistically difference (P <0.01).Conclusion The application of cell phone health management software in outpatients has a positive effect on patients' health management, which is worthy of clinical promotion.

  11. Quantitative imaging with a mobile phone microscope.

    Directory of Open Access Journals (Sweden)

    Arunan Skandarajah

    Full Text Available Use of optical imaging for medical and scientific applications requires accurate quantification of features such as object size, color, and brightness. High pixel density cameras available on modern mobile phones have made photography simple and convenient for consumer applications; however, the camera hardware and software that enables this simplicity can present a barrier to accurate quantification of image data. This issue is exacerbated by automated settings, proprietary image processing algorithms, rapid phone evolution, and the diversity of manufacturers. If mobile phone cameras are to live up to their potential to increase access to healthcare in low-resource settings, limitations of mobile phone-based imaging must be fully understood and addressed with procedures that minimize their effects on image quantification. Here we focus on microscopic optical imaging using a custom mobile phone microscope that is compatible with phones from multiple manufacturers. We demonstrate that quantitative microscopy with micron-scale spatial resolution can be carried out with multiple phones and that image linearity, distortion, and color can be corrected as needed. Using all versions of the iPhone and a selection of Android phones released between 2007 and 2012, we show that phones with greater than 5 MP are capable of nearly diffraction-limited resolution over a broad range of magnifications, including those relevant for single cell imaging. We find that automatic focus, exposure, and color gain standard on mobile phones can degrade image resolution and reduce accuracy of color capture if uncorrected, and we devise procedures to avoid these barriers to quantitative imaging. By accommodating the differences between mobile phone cameras and the scientific cameras, mobile phone microscopes can be reliably used to increase access to quantitative imaging for a variety of medical and scientific applications.

  12. New insights into the epigenetic control of satellite cells

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Epigenetics finely tunes gene expression at a functionallevel without modifying the DNA sequence, therebycontributing to the complexity of genomic regulation.Satellite cells (SCs) are adult muscle stem cells thatare important for skeletal post-natal muscle growth,homeostasis and repair. The understanding of theepigenome of SCs at different stages and of themultiple layers of the post-transcriptional regulationof gene expression is constantly expanding. Dynamicinteractions between different epigenetic mechanismsregulate the appropriate timing of muscle-specific geneexpression and influence the lineage fate of SCs. Inthis review, we report and discuss the recent literatureabout the epigenetic control of SCs during the myogenicprocess from activation to proliferation and from theircommitment to a muscle cell fate to their differentiationand fusion to myotubes. We describe how the coordinatedactivities of the histone methyltransferasefamilies Polycomb group (PcG), which represses theexpression of developmentally regulated genes, andTrithorax group, which antagonizes the repressive activityof the PcG, regulate myogenesis by restricting geneexpression in a time-dependent manner during eachstep of the process. We discuss how histone acetylationand deacetylation occurs in specific loci throughoutSC differentiation to enable the time-dependent transcriptionof specific genes. Moreover, we describe themultiple roles of microRNA, an additional epigeneticmechanism, in regulating gene expression in SCs, byrepressing or enhancing gene transcription or translationduring each step of myogenesis. The importance ofthese epigenetic pathways in modulating SC activationand differentiation renders them as promising targetsfor disease interventions. Understanding the mostrecent findings regarding the epigenetic mechanismsthat regulate SC behavior is useful from the perspectiveof pharmacological manipulation for improving muscleregeneration and for promoting muscle homeostasisunder

  13. Cellular Phone Towers, Cell tower locations in the County of Polk, Wisconsin used for Emergency Management purposes only., Published in 2006, 1:2400 (1in=200ft) scale, Polk County, Wisconsin.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Other information as of 2006. It is described as 'Cell...

  14. Cellular Phone Towers, Cell tower locations as derived from various sources including the Department of Licenses and Inspections and the Department of Planning and Zoning., Published in 2010, 1:2400 (1in=200ft) scale, Howard County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Cellular Phone Towers dataset current as of 2010. Cell tower locations as derived from various sources including the Department of Licenses and Inspections and the...

  15. The heat-shock factor is not activated in mammalian cells exposed to cellular phone frequency microwaves.

    Science.gov (United States)

    Laszlo, Andrei; Moros, Eduardo G; Davidson, Teri; Bradbury, Matt; Straube, William; Roti Roti, Joseph

    2005-08-01

    There has been considerable interest in the biological effects of exposure to radiofrequency electromagnetic radiation, given the explosive growth of cellular telephone use, with the possible induction of malignancy being a significant concern. Thus the determination of whether nonthermal effects of radiofrequency electromagnetic radiation contribute to the process leading to malignancy is an important task. One proposed pathway to malignancy involves the induction of the stress response by exposures to cell phone frequency microwaves. The first step in the induction of the stress response is the activation of the DNA-binding activity of the specific transcription factor involved in this response, the heat-shock factor (HSF). The DNA-binding activity of HSF in hamster, mouse and human cells was determined after acute and continuous exposures to frequency domain multiple access (FDMA)- or code domain multiple access (CDMA)-modulated microwaves at low (0.6 W/kg) or high (approximately 5 W/kg) SARs at frequencies used for mobile communication. The DNA-binding activity of HSF was monitored using a gel shift assay; the calibration of this assay indicated that an increase of approximately 10% in the activation of the DNA-binding activity of HSF after a 1 degrees C increase in temperature could be detected. We failed to detect any increase in the DNA-binding ability of HSF in cultured mammalian cells as a consequence of any exposure tested, within the sensitivity of our assay. Our results do not support the notion that the stress response is activated as a consequence of exposure to microwaves of frequencies associated with mobile communication devices.

  16. No increase in brain cancer rates during period of expanding cell phone use

    Science.gov (United States)

    In a new examination of United States cancer incidence data, investigators at the National Cancer Institute (NCI) reported that incidence trends have remained roughly constant for glioma, the main type of brain cancer hypothesized to be related to cell ph

  17. File list: Oth.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 TFs and others Muscle Satellite Cells, Skeletal... Muscle SRX818829,SRX818831,SRX818828,SRX818830 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  18. File list: His.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 Histone Muscle Satellite Cells, Skeletal... Muscle SRX818827,SRX818825,SRX818826 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  19. File list: ALL.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 All antigens Muscle Satellite Cells, Skeletal...18833,SRX818834 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  20. File list: ALL.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 All antigens Muscle Satellite Cells, Skeletal...18834,SRX818832 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  1. File list: ALL.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 All antigens Muscle Satellite Cells, Skeletal...18830,SRX818832 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  2. File list: NoD.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 No description Muscle Satellite Cells, Skeletal... Muscle http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/NoD.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  3. File list: Unc.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 Unclassified Muscle Satellite Cells, Skeletal... Muscle http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Unc.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  4. File list: Pol.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 RNA polymerase Muscle Satellite Cells, Skeletal... Muscle http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Pol.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  5. File list: DNS.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 DNase-seq Muscle Satellite Cells, Skeletal... Muscle http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/DNS.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  6. File list: Oth.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 TFs and others Muscle Satellite Cells, Skeletal... Muscle SRX818829,SRX818828,SRX818830,SRX818831 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  7. File list: NoD.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 No description Muscle Satellite Cells, Skeletal... Muscle http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/NoD.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  8. File list: Unc.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 Unclassified Muscle Satellite Cells, Skeletal... Muscle http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Unc.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  9. File list: Oth.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 TFs and others Muscle Satellite Cells, Skeletal... Muscle SRX818831,SRX818829,SRX818828,SRX818830 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  10. File list: NoD.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 No description Muscle Satellite Cells, Skeletal... Muscle http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/NoD.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  11. File list: InP.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 Input control Muscle Satellite Cells, Skeletal... Muscle SRX818833,SRX818834,SRX818832 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  12. File list: His.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 Histone Muscle Satellite Cells, Skeletal... Muscle SRX818827,SRX818825,SRX818826 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  13. File list: DNS.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 DNase-seq Muscle Satellite Cells, Skeletal... Muscle http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/DNS.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  14. File list: ALL.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 All antigens Muscle Satellite Cells, Skeletal...18832,SRX818833 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  15. File list: NoD.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 No description Muscle Satellite Cells, Skeletal... Muscle http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/NoD.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  16. File list: His.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 Histone Muscle Satellite Cells, Skeletal... Muscle SRX818826,SRX818827,SRX818825 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  17. File list: InP.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 Input control Muscle Satellite Cells, Skeletal Muscle... SRX818834,SRX818832,SRX818833 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  18. File list: Pol.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 RNA polymerase Muscle Satellite Cells, Skeletal Muscle... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Pol.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  19. File list: DNS.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 DNase-seq Muscle Satellite Cells, Skeletal Muscle... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/DNS.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  20. File list: Pol.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 RNA polymerase Muscle Satellite Cells, Skeletal Muscle... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Pol.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  1. File list: Pol.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 RNA polymerase Muscle Satellite Cells, Skeletal Muscle... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Pol.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  2. File list: Unc.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 Unclassified Muscle Satellite Cells, Skeletal Muscle... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Unc.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  3. File list: Oth.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 TFs and others Muscle Satellite Cells, Skeletal Muscle... SRX818829,SRX818828,SRX818830,SRX818831 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  4. File list: Unc.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 Unclassified Muscle Satellite Cells, Skeletal Muscle... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Unc.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  5. File list: InP.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 Input control Muscle Satellite Cells, Skeletal Muscle... SRX818832,SRX818833,SRX818834 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.Myo.50.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  6. File list: InP.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 Input control Muscle Satellite Cells, Skeletal Muscle... SRX818833,SRX818834,SRX818832 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.Myo.05.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  7. File list: DNS.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 DNase-seq Muscle Satellite Cells, Skeletal Muscle... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/DNS.Myo.20.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  8. File list: His.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle mm9 Histone Muscle Satellite Cells, Skeletal Muscle... SRX818827,SRX818826,SRX818825 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.Myo.10.AllAg.Satellite_Cells,_Skeletal_Muscle.bed ...

  9. A simplified but robust method for the isolation of avian and mammalian muscle satellite cells

    Directory of Open Access Journals (Sweden)

    Baquero-Perez Belinda

    2012-06-01

    Full Text Available Abstract Background Current methods of isolation of muscle satellite cells from different animal species are highly variable making inter-species comparisons problematic. This variation mainly stems from the use of different proteolytic enzymes to release the satellite cells from the muscle tissue (sometimes a single enzyme is used but often a combination of enzymes is preferred and the different extracellular matrix proteins used to coat culture ware. In addition, isolation of satellite cells is frequently laborious and sometimes may require pre-plating of the cell preparation on uncoated flasks or Percoll centrifugation to remove contaminating fibroblasts. The methodology employed to isolate and culture satellite cells in vitro can critically determine the fusion of myoblasts into multi-nucleated myotubes. These terminally differentiated myotubes resemble mature myofibres in the muscle tissue in vivo, therefore optimal fusion is a keystone of in vitro muscle culture. Hence, a simple method of muscle satellite cell isolation and culture of different vertebrate species that can result in a high fusion rate is highly desirable. Results We demonstrate here a relatively simple and rapid method of isolating highly enriched muscle satellite cells from different avian and mammalian species. In brief, muscle tissue was mechanically dissociated, digested with a single enzyme (pronase, triturated with a 10-ml pipette, filtered and directly plated onto collagen coated flasks. Following this method and after optimization of the cell culture conditions, excellent fusion rates were achieved in the duck, chicken, horse and cow (with more than 50% cell fusion, and to a lesser extent pig, pointing to pronase as a highly suitable enzyme to release satellite cells from muscle tissue. Conclusions Our simplified method presents a quick and simple alternative to isolating highly enriched muscle satellite cell cultures which can subsequently rapidly differentiate

  10. Cellular phones: are they detrimental?

    Science.gov (United States)

    Salama, Osama E; Abou El Naga, Randa M

    2004-01-01

    The issue of possible health effects of cellular phones is very much alive in the public's mind where the rapid increase in the number of the users of cell phones in the last decade has increased the exposure of people to the electromagnetic fields (EMFs). Health consequences of long term use of mobile phones are not known in detail but available data indicates the development of non specific annoying symptoms on acute exposure to mobile phone radiations. In an attempt to determine the prevalence of such cell phones associated health manifestations and the factors affecting their occurrence, a cross sectional study was conducted in five randomly selected faculties of Alexandria University. Where, 300 individuals including teaching staff, students and literate employee were equally allocated and randomly selected among the five faculties. Data about mobile phone's users and their medical history, their pattern of mobile usage and the possible deleterious health manifestations associated with cellular phone use was collected. The results revealed 68% prevalence of mobile phone usage, nearly three quarters of them (72.5%) were complainers of the health manifestations. They suffered from headache (43%), earache (38.3%), sense of fatigue (31.6%), sleep disturbance (29.5%), concentration difficulty (28.5%) and face burning sensation (19.2%). Both univariate and multivariate analysis were consistent in their findings. Symptomatic users were found to have significantly higher frequency of calls/day, longer call duration and longer total duration of mobile phone usage/day than non symptomatic users. For headache both call duration and frequency of calls/day were the significant predicting factors for its occurrence (chi2 = 18.208, p = 0.0001). For earache, in addition to call duration, the longer period of owning the mobile phone were significant predictors (chi2 = 16.996, p = 0.0002). Sense of fatigue was significantly affected by both call duration and age of the user

  11. Breast cancer prevention information seeking behavior and interest on cell phone and text use: a cross-sectional study in Malaysia.

    Science.gov (United States)

    Akhtari-Zavare, Mehrnoosh; Ghanbari-Baghestan, Abbas; Latiff, Latiffah A; Khaniki, Hadi

    2015-01-01

    Breast cancer is the most common cancer and the second principal cause of cancer deaths among women worldwide, including Malaysia. This study focused on media choice and attempted to determine the communication channels mostly used and preferred by women in seeking information and knowledge about breast cancer. A cross sectional study was carried out to examine the breast cancer prevention information seeking behavior among 450 students at one private university in Malaysia. The mean age of respondents was 25±4.3 years. Common interpersonal information sources were doctors, friends, and nurses and common channel information sources were television, brochure, and internet. Overall, 89.9% used cell phones, 46.1% had an interest in receiving cell phone breast cancer prevention messages, 73.9% used text messaging, and 36.7% had an interest in receiving text breast cancer prevention messages. Bivariate analysis revealed significant differences among age, eduation, nationality and use of cell phones. Assessment of health information seeking behavior is important for community health educators to target populations for program development.

  12. The behaviour of satellite cells in response to exercise: what have we learned from human studies?

    DEFF Research Database (Denmark)

    Kadi, Fawzi; Olsen, Steen Schytte

    2005-01-01

    Understanding the complex role played by satellite cells in the adaptive response to exercise in human skeletal muscle has just begun. The development of reliable markers for the identification of satellite cell status (quiescence/activation/proliferation) is an important step towards the underst......Understanding the complex role played by satellite cells in the adaptive response to exercise in human skeletal muscle has just begun. The development of reliable markers for the identification of satellite cell status (quiescence/activation/proliferation) is an important step towards...... the understanding of satellite cell behaviour in exercised human muscles. It is hypothesised currently that exercise in humans can induce (1) the activation of satellite cells without proliferation, (2) proliferation and withdrawal from differentiation, (3) proliferation and differentiation to provide myonuclei...... and (4) proliferation and differentiation to generate new muscle fibres or to repair segmental fibre injuries. In humans, the satellite cell pool can increase as early as 4 days following a single bout of exercise and is maintained at higher level following several weeks of training. Cessation...

  13. Satellited 4q identified in amniotic fluid cells

    Energy Technology Data Exchange (ETDEWEB)

    Miller, I.; Hsieh, C.L.; Songster, G. [Stanford Univ. Medical Center, Stanford, CA (United States)] [and others

    1995-01-16

    Extra material was identified on the distal long arm of a chromosome 4 in an amniotic fluid specimen sampled at 16.6 weeks of gestational age. There was no visible loss of material from chromosome 4, and no evidence for a balanced rearrangement. The primary counseling issue in this case was advanced maternal age. Ultrasound findings were normal, and family history was unremarkable. The identical 4qs chromosome was observed in cells from a paternal peripheral blood specimen and appeared to be an unbalanced rearrangement. This extra material was NOR positive in lymphocytes from the father, but was negative in the fetal amniocytes. Father`s relatives were studied to verify the familial origin of this anomaly. In situ hybridization with both exon and intron sequences of ribosomal DNA demonstrated that ribosomal DNA is present at the terminus of the 4qs chromosome in the fetus, father, and paternal grandmother. This satellited 4q might have been derived from a translocation event that resulted in very little or no loss from the 4q and no specific phenotype. This derivative chromosome 4 has been inherited through at least 3 generations of phenotypically normal individuals. 8 refs., 3 figs.

  14. Satellite cell activity, without expansion, after nonhypertrophic stimuli.

    Science.gov (United States)

    Joanisse, Sophie; McKay, Bryon R; Nederveen, Joshua P; Scribbans, Trisha D; Gurd, Brendon J; Gillen, Jenna B; Gibala, Martin J; Tarnopolsky, Mark; Parise, Gianni

    2015-11-01

    The purpose of the present studies was to determine the effect of various nonhypertrophic exercise stimuli on satellite cell (SC) pool activity in human skeletal muscle. Previously untrained men and women (men: 29 ± 9 yr and women: 29 ± 2 yr, n = 7 each) completed 6 wk of very low-volume high-intensity sprint interval training. In a separate study, recreationally active men (n = 16) and women (n = 3) completed 6 wk of either traditional moderate-intensity continuous exercise (n = 9, 21 ± 4 yr) or low-volume sprint interval training (n = 10, 21 ± 2 yr). Muscle biopsies were obtained from the vastus lateralis before and after training. The fiber type-specific SC response to training was determined, as was the activity of the SC pool using immunofluorescent microscopy of muscle cross sections. Training did not induce hypertrophy, as assessed by muscle cross-sectional area, nor did the SC pool expand in any group. However, there was an increase in the number of active SCs after each intervention. Specifically, the number of activated (Pax7(+)/MyoD(+), P ≤ 0.05) and differentiating (Pax7(-)/MyoD(+), P ≤ 0.05) SCs increased after each training intervention. Here, we report evidence of activated and cycling SCs that may or may not contribute to exercise-induced adaptations while the SC pool remains constant after three nonhypertrophic exercise training protocols.

  15. Theoretical Investigation of Laser-Radiation Effects on Satellite Solar Cells

    Science.gov (United States)

    Abdel-Hadi, Yasser; El-Hameed, Afaf; Hamdy, Ola

    This research concerns with the studying of laser-powered solar panels for space applications. A model describing the laser effects on satellite solar cell has been developed. These effects are studied theoretically in order to determine the performance limits of the solar cells when they are powered by laser radiation during the satellite eclipse. A comparison between some different common types of the solar cells used for these purpose is considered in this study. The obtained results are reported to optimize the use of laser-powered satellites.

  16. Siri of the cell: what biology could learn from the iPhone.

    Science.gov (United States)

    Carvunis, Anne-Ruxandra; Ideker, Trey

    2014-04-24

    Modern genomics is very efficient at mapping genes and gene networks, but how to transform these maps into predictive models of the cell remains unclear. Recent progress in computer science, embodied by intelligent agents such as Siri, inspires an approach for moving from networks to multiscale models able to predict a range of cellular phenotypes and answer biological questions.

  17. Internet Use for Health-Related Information via Personal Computers and Cell Phones in Japan: A Cross-Sectional Population-Based Survey

    Science.gov (United States)

    Takahashi, Yoshimitsu; Ohura, Tomoko; Ishizaki, Tatsuro; Okamoto, Shigeru; Miki, Kenji; Naito, Mariko; Akamatsu, Rie; Sugimori, Hiroki; Yoshiike, Nobuo; Miyaki, Koichi; Shimbo, Takuro

    2011-01-01

    Background The Internet is known to be used for health purposes by the general public all over the world. However, little is known about the use of, attitudes toward, and activities regarding eHealth among the Japanese population. Objectives This study aimed to measure the prevalence of Internet use for health-related information compared with other sources, and to examine the effects on user knowledge, attitudes, and activities with regard to Internet use for health-related information in Japan. We examined the extent of use via personal computers and cell phones. Methods We conducted a cross-sectional survey of a quasi-representative sample (N = 1200) of the Japanese general population aged 15–79 years in September 2007. The main outcome measures were (1) self-reported rates of Internet use in the past year to acquire health-related information and to contact health professionals, family, friends, and peers specifically for health-related purposes, and (2) perceived effects of Internet use on health care. Results The prevalence of Internet use via personal computer for acquiring health-related information was 23.8% (286/1200) among those surveyed, whereas the prevalence via cell phone was 6% (77). Internet use via both personal computer and cell phone for communicating with health professionals, family, friends, or peers was not common. The Internet was used via personal computer for acquiring health-related information primarily by younger people, people with higher education levels, and people with higher household incomes. The majority of those who used the Internet for health care purposes responded that the Internet improved their knowledge or affected their lifestyle attitude, and that they felt confident in the health-related information they obtained from the Internet. However, less than one-quarter thought it improved their ability to manage their health or affected their health-related activities. Conclusions Japanese moderately used the Internet via

  18. Quantitative Imaging with a Mobile Phone Microscope

    Science.gov (United States)

    Skandarajah, Arunan; Reber, Clay D.; Switz, Neil A.; Fletcher, Daniel A.

    2014-01-01

    Use of optical imaging for medical and scientific applications requires accurate quantification of features such as object size, color, and brightness. High pixel density cameras available on modern mobile phones have made photography simple and convenient for consumer applications; however, the camera hardware and software that enables this simplicity can present a barrier to accurate quantification of image data. This issue is exacerbated by automated settings, proprietary image processing algorithms, rapid phone evolution, and the diversity of manufacturers. If mobile phone cameras are to live up to their potential to increase access to healthcare in low-resource settings, limitations of mobile phone–based imaging must be fully understood and addressed with procedures that minimize their effects on image quantification. Here we focus on microscopic optical imaging using a custom mobile phone microscope that is compatible with phones from multiple manufacturers. We demonstrate that quantitative microscopy with micron-scale spatial resolution can be carried out with multiple phones and that image linearity, distortion, and color can be corrected as needed. Using all versions of the iPhone and a selection of Android phones released between 2007 and 2012, we show that phones with greater than 5 MP are capable of nearly diffraction-limited resolution over a broad range of magnifications, including those relevant for single cell imaging. We find that automatic focus, exposure, and color gain standard on mobile phones can degrade image resolution and reduce accuracy of color capture if uncorrected, and we devise procedures to avoid these barriers to quantitative imaging. By accommodating the differences between mobile phone cameras and the scientific cameras, mobile phone microscopes can be reliably used to increase access to quantitative imaging for a variety of medical and scientific applications. PMID:24824072

  19. Mobile Phones on Campus

    Institute of Scientific and Technical Information of China (English)

    朴春宝

    2007-01-01

    After entering the 21st century, more and more people have mobile phones in China. At the end of 2002, there were 20 million mobile phone users. By the year 2005 the number has reached up to 30 million.

  20. Regulation of the muscle fiber microenvironment by activated satellite cells during hypertrophy.

    Science.gov (United States)

    Fry, Christopher S; Lee, Jonah D; Jackson, Janna R; Kirby, Tyler J; Stasko, Shawn A; Liu, Honglu; Dupont-Versteegden, Esther E; McCarthy, John J; Peterson, Charlotte A

    2014-04-01

    Our aim in the current study was to determine the necessity of satellite cells for long-term muscle growth and maintenance. We utilized a transgenic Pax7-DTA mouse model, allowing for the conditional depletion of > 90% of satellite cells with tamoxifen treatment. Synergist ablation surgery, where removal of synergist muscles places functional overload on the plantaris, was used to stimulate robust hypertrophy. Following 8 wk of overload, satellite cell-depleted muscle demonstrated an accumulation of extracellular matrix (ECM) and fibroblast expansion that resulted in reduced specific force of the plantaris. Although the early growth response was normal, an attenuation of hypertrophy measured by both muscle wet weight and fiber cross-sectional area occurred in satellite cell-depleted muscle. Isolated primary myogenic progenitor cells (MPCs) negatively regulated fibroblast ECM mRNA expression in vitro, suggesting a novel role for activated satellite cells/MPCs in muscle adaptation. These results provide evidence that satellite cells regulate the muscle environment during growth.

  1. Local NSAID infusion inhibits satellite cell proliferation in human skeletal muscle after eccentric exercise

    DEFF Research Database (Denmark)

    Mikkelsen, U R; Langberg, H; Helmark, I C

    2009-01-01

    exercise in vivo in human skeletal muscle. Eight young healthy males performed 200 maximal eccentric contractions with each leg. An NSAID was infused via a microdialysis catheter into the vastus lateralis muscle of one leg (NSAID leg) before, during, and for 4.5 h after exercise, with the other leg working...... of satellite cells 8 days after exercise. These results suggest that NSAIDs negatively affect satellite cell activity after unaccustomed eccentric exercise.......Despite the widespread consumption of nonsteroidal anti-inflammatory drugs (NSAIDs), the influence of these drugs on muscle satellite cells is not fully understood. The aim of the present study was to investigate the effect of a local NSAID infusion on satellite cells after unaccustomed eccentric...

  2. The quasi-parallel lives of satellite cells and atrophying muscle

    Directory of Open Access Journals (Sweden)

    Stefano eBiressi

    2015-07-01

    Full Text Available Skeletal muscle atrophy or wasting accompanies various chronic illnesses and the aging process, thereby reducing muscle function. One of the most important components contributing to effective muscle repair in postnatal organisms, the satellite cells, have recently become the focus of several studies examining factors participating in the atrophic process. We critically examine here the experimental evidence linking satellite cell function with muscle loss in connection with various diseases as well as aging, and in the subsequent recovery process. Several recent reports have investigated the changes in satellite cells in terms of their differentiation and proliferative capacity in response to various atrophic stimuli. In this regard, we review the molecular changes within satellite cells that contribute to their dysfunctional status in atrophy, with the intention of shedding light on novel potential pharmacological targets to counteract the loss of muscle mass.

  3. Investigating the effects of 217 Hz frequency of cell phone on learning and spatial memory in rats

    Directory of Open Access Journals (Sweden)

    Kohzad S

    2013-03-01

    Full Text Available Background: Extremely low frequency (0-300 Hz fields from power lines, electronic equipment and medical devices, have been reported to produce various biological effects. Global system for mobile (GSM is most largely used in everybody's life. This system utilizes a low frequency band as well as a high frequency range of electromagnetic field. This study investigated the effects of 217 Hz electromagnetic field (the modulating signal in GSM on spatial learning and memory in rat.Methods: Twenty four male Wistar rat (200- 250 g were randomly divided in to three groups as: test, sham and control. Using a Helmholtz coil system, the test group was exposed to a uniform pulsed EMF of 200 µT (micro Tesla intensity for 4 h/day for 21 days (2 time in a day. This procedure was repeated for the sham group but with no field. All groups were trained prior to the day 21 on the 15th day for five days four trial per day in Morris Water-Maze system. Then the probe test was carried out for 60 seconds with no platform.Results: The ANOVA test revealed that no significant differences were found between control and exposed rats in all day of learning acquisition. Also, in probe test for investigating the memory, no significant differences observed. (P≤0.05 is accepted for significant level.Conclusion: This finding is in consistent with previous studies and indicates low frequency band of electromagnetic fields (EMF (200 µT intensity in cell phone may not have any effect on the learning acquisition and spatial memory in rat.

  4. Aquarius iPhone Application

    Science.gov (United States)

    Estes, Joseph C., Jr.; Arca. Jeremy M.; Ko, Michael A.; Oks, Boris

    2012-01-01

    The Office of the CIO at JPL has developed an iPhone application for the Aquarius/SAC-D mission. The application includes specific information about the science and purpose of the Aquarius satellite and also features daily mission news updates pulled from sources at Goddard Space Flight Center as well as Twitter. The application includes a media and data tab section. The media section displays images from the observatory, viewing construction up to the launch and also includes various videos and recorded diaries from the Aquarius Project Manager. The data tab highlights many of the factors that affect the Earth s ocean and the water cycle. The application leverages the iPhone s accelerometer to move the Aquarius Satellite over the Earth, revealing these factors. Lastly, this application features a countdown timer to the satellite s launch, which is currently counting the days since launch. This application was highly successful in promoting the Aquarius Mission and educating the public about how ocean salinity is paramount to understanding the Earth.

  5. Gap junctional communication between the satellite cells of rat dorsal root ganglia.

    Science.gov (United States)

    Sakuma, E; Wang, H J; Asai, Y; Tamaki, D; Amano, K; Mabuchi, Y; Herbert, D C; Soji, T

    2001-06-01

    Many studies have described the ultrastructure of the dorsal root ganglia in various embryonic and adult animals, but in spite of the efforts of many investigators the functional role of the satellite cells in this tissue is not clearly understood. In this study, we discuss the function of this cell type based on the concept of cell-to-cell interaction through gap junctions. Five male 60 day-old Wistar strain rats were used. All animals were anesthetized with pentobarbital and perfused with glutaraldehyde fixative, then the dorsal root ganglia in levels L4, L5 and L6 were taken from each rat. After postosmication, the specimens were prepared for observation by transmission electron microscopy. All nerve cells were completely surrounded by satellite cell cytoplasmic expansions. The boundaries between adjacent nerve cells and satellite cells were complicated due to the presence of perikaryal projections of nerve cells. Gap junctions which showed the typical trilamellar structure of plasma membranes were found mainly between satellite cell processes belonging to the same nerve cell. On the other hand, some gap junctions were found between the satellite cell projections belonging to different nerve cells. The size of the gap junctions ranged from 300 to 400 nm. No gap junctions were associated with the plasma membrane of any nerve cell. In conclusion, only satellite cells can share free transcellular exchange of cytoplasmic molecules such as ions, amino acids, sugars and several second messengers including cAMP and inositol 1,4,5-triphosphate by way of gap junctions in dorsal root ganglia.

  6. Mobile phone and my health

    Energy Technology Data Exchange (ETDEWEB)

    Surducan, Aneta [Nicolae Balcescu High School, 6 Constanta St., 400158 Cluj-Napoca (Romania); Dabala, Dana [National Railways Medical Clinic,, Occupational Medicine Department, 16-20 Republicii St., 400015 Cluj-Napoca (Romania); Neamtu, Camelia, E-mail: emanoil.surducan@itim-cj.ro; Surducan, Vasile, E-mail: emanoil.surducan@itim-cj.ro; Surducan, Emanoil, E-mail: emanoil.surducan@itim-cj.ro [National Institute for Research and Development of Isotopic and Molecular Technologies, 65-103 Donath St., 400293 Cluj-Napoca (Romania)

    2013-11-13

    The interaction of the microwave radiation emitted by mobile phones with the user's body is analyzed from the International Commission on Non-Ionizing Radiation Protection (ICNIRP) recommendations perspective as a correlation between the specific absorption ratio (SAR) of the mobile phone and the call duration. The relative position of the cell phone to the user's body, the dielectric properties of the exposed body parts, the SAR value and the call duration are considered in the local body temperature rise due to the microwave heating effect. The recommended local temperature rise limit in the human body is evaluated according to standards. The aim of this study is to disseminate information to young people, especially high school students, about the microwave thermal effects on the human body, to make them aware of the environmental electromagnetic pollution and to offer them a simple method of biological self protection.

  7. Mobile phone and my health

    Science.gov (United States)

    Surducan, Aneta; Dabala, Dana; Neamtu, Camelia; Surducan, Vasile; Surducan, Emanoil

    2013-11-01

    The interaction of the microwave radiation emitted by mobile phones with the user's body is analyzed from the International Commission on Non-Ionizing Radiation Protection (ICNIRP) recommendations perspective as a correlation between the specific absorption ratio (SAR) of the mobile phone and the call duration. The relative position of the cell phone to the user's body, the dielectric properties of the exposed body parts, the SAR value and the call duration are considered in the local body temperature rise due to the microwave heating effect. The recommended local temperature rise limit in the human body is evaluated according to standards. The aim of this study is to disseminate information to young people, especially high school students, about the microwave thermal effects on the human body, to make them aware of the environmental electromagnetic pollution and to offer them a simple method of biological self protection.

  8. 网络和手机对在校大学生的影响%The Impact of Network and Cell Phones to College Students

    Institute of Scientific and Technical Information of China (English)

    张凡

    2014-01-01

    “网络文化”和“手机文化”已经成为大学校园中的一种新的文化现象。网络信息资源的丰富和交流的便捷,深得大学生们的关注和喜爱。然而由于种种原因,网络和手机对大学生产生了很多消极影响,我们应该消除这些影响,并教育和引导大学生文明使用网络和手机。%"Internet culture"and"cell phone culture"has become a university campus in a new cultural phenomenon. Rich network of information resources and communication convenience, the students won the attention and love. However, due to various reasons, the network and the mobile phone of college students have a lot of negative impact, we should eliminate the-se effects, and to educate and guide students to use the Internet and mobile phones civilization.

  9. The effects of cell phone electromagnetic fields on the behavior of single OmpF nanochannel forming protein: a practical approach

    Directory of Open Access Journals (Sweden)

    Mohammadzadeh M

    2013-05-01

    Full Text Available Background: Widespread of telecommunication systems in recent years, have raised the concerns on the possible danger of cell phone radiations on human body. Thus, the study of the electromagnetic fields on proteins, particularly the membrane nano channel forming proteins is of great importance. These proteins are responsible for keeping certain physic-chemical condition within cells and managing cell communication. Here, the effects of cell phones radiation on the activity of a single nanopore ion channel forming protein, OmpF, have been studied biophysically.Methods: Planar lipid bilayers were made based on Montal and Muller technique, and the activity of single OmpF channel reconstituted by electrical shock was recorded and analyzed by means of voltage-clamp technique at 20 ˚C. The planar lipid bilayers were formed from the monolayers made on a 60 μm diameter aperture in the 20 μm thick Teflon film that separated two (cis and trans compartments of the glass chamber. In this practical approach we were able to analyze characteristics of an individual channel at different chemical and physical experimental conditions. The voltage clamp was used to measure the channel’s conductance, voltage sensitivity, gating patterns in time scales as low as microseconds in real time.  Results: Our results showed that exposure of single voltage dependent channel, OmpF, to EMF of cell phone at high-frequency has a significant influence on the voltage sensitivity, gating properties and substate numbers of the single channel but has no effect on single-channel conductance. Regarding to the relaxation time, the channel also recovers in the millisecond time range when the field is removed. Conclusion: We observed an increase in the voltage sensitivity of the OmpF single channel while it had no effect on the single-channel conductance, which is remained to be further elucidated.

  10. Reduced satellite cell population may lead to contractures in children with cerebral palsy.

    Science.gov (United States)

    Smith, Lucas R; Chambers, Henry G; Lieber, Richard L

    2013-03-01

    Satellite cells are the stem cells residing in muscle responsible for skeletal muscle growth and repair. Skeletal muscle in cerebral palsy (CP) has impaired longitudinal growth that results in muscle contractures. We hypothesized that the satellite cell population would be reduced in contractured muscle. We compared the satellite cell populations in hamstring muscles from participants with CP contracture (n=8; six males, two females; age range 6-15y; Gross Motor Function Classification System [GMFCS] levels II-V; 4 with hemiplegia, 4 with diplegia) and from typically developing participants (n=8; six males, two females, age range 15-18y). Muscle biopsies were extracted from the gracilis and semitendinosus muscles and mononuclear cells were isolated. Cell surface markers were stained with fluorescently conjugated antibodies to label satellite cells (neural cell adhesion molecule) and inflammatory and endothelial cells (CD34 and CD4 respectively). Cells were analyzed using flow cytometry to determine cell populations. After gating for intact cells a mean of 12.8% (SD 2.8%) were determined to be satellite cells in typically developing children, but only 5.3% (SD 2.3%; p0.05) suggesting the isolation procedure was valid. A reduced satellite cell population may account for the decreased longitudinal growth of muscles in CP that develop into fixed contractures or the decreased ability to strengthen muscle in CP. This suggests a unique musculoskeletal disease mechanism and provides a potential therapeutic target for debilitating muscle contractures. © The Authors. Developmental Medicine & Child Neurology © 2012 Mac Keith Press.

  11. mTOR is necessary for proper satellite cell activity and skeletal muscle regeneration

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Pengpeng [Key Laboratory of Swine Genetics and Breeding of Agricultural Ministry & Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070 (China); Department of Animal Sciences, Purdue University, West Lafayette, IN 47907 (United States); Liang, Xinrong; Shan, Tizhong [Department of Animal Sciences, Purdue University, West Lafayette, IN 47907 (United States); Jiang, Qinyang [Department of Animal Sciences, Purdue University, West Lafayette, IN 47907 (United States); College of Animal Science and Technology, Guangxi University, Nanning 530004 (China); Deng, Changyan [Key Laboratory of Swine Genetics and Breeding of Agricultural Ministry & Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070 (China); Zheng, Rong, E-mail: zhengrong@mail.hzau.edu.cn [Key Laboratory of Swine Genetics and Breeding of Agricultural Ministry & Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070 (China); Kuang, Shihuan, E-mail: skuang@purdue.edu [Department of Animal Sciences, Purdue University, West Lafayette, IN 47907 (United States)

    2015-07-17

    The serine/threonine kinase mammalian target of rapamycin (mTOR) is a key regulator of protein synthesis, cell proliferation and energy metabolism. As constitutive deletion of Mtor gene results in embryonic lethality, the function of mTOR in muscle stem cells (satellite cells) and skeletal muscle regeneration remains to be determined. In this study, we established a satellite cell specific Mtor conditional knockout (cKO) mouse model by crossing Pax7{sup CreER} and Mtor{sup flox/flox} mice. Skeletal muscle regeneration after injury was severely compromised in the absence of Mtor, indicated by increased number of necrotic myofibers infiltrated by Evans blue dye, and reduced number and size of regenerated myofibers in the Mtor cKO mice compared to wild type (WT) littermates. To dissect the cellular mechanism, we analyzed satellite cell-derived primary myoblasts grown on single myofibers or adhered to culture plates. The Mtor cKO myoblasts exhibited defective proliferation and differentiation kinetics when compared to myoblasts derived from WT littermates. At the mRNA and protein levels, the Mtor cKO myoblasts expressed lower levels of key myogenic determinant genes Pax7, Myf5, Myod, Myog than did the WT myoblasts. These results suggest that mTOR is essential for satellite cell function and skeletal muscle regeneration through controlling the expression of myogenic genes. - Highlights: • Pax7{sup CreER} was used to delete Mtor gene in satellite cells. • Satellite cell specific deletion of Mtor impairs muscle regeneration. • mTOR is necessary for satellite cell proliferation and differentiation. • Deletion of Mtor leads to reduced expression of key myogenic genes.

  12. Conditional Cripto overexpression in satellite cells promotes myogenic commitment and enhances early regeneration.

    Science.gov (United States)

    Prezioso, Carolina; Iaconis, Salvatore; Andolfi, Gennaro; Zentilin, Lorena; Iavarone, Francescopaolo; Guardiola, Ombretta; Minchiotti, Gabriella

    2015-01-01

    Skeletal muscle regeneration mainly depends on satellite cells, a population of resident muscle stem cells. Despite extensive studies, knowledge of the molecular mechanisms underlying the early events associated with satellite cell activation and myogenic commitment in muscle regeneration remains still incomplete. Cripto is a novel regulator of postnatal skeletal muscle regeneration and a promising target for future therapy. Indeed, Cripto is expressed both in myogenic and inflammatory cells in skeletal muscle after acute injury and it is required in the satellite cell compartment to achieve effective muscle regeneration. A critical requirement to further explore the in vivo cellular contribution of Cripto in regulating skeletal muscle regeneration is the possibility to overexpress Cripto in its endogenous configuration and in a cell and time-specific manner. Here we report the generation and the functional characterization of a novel mouse model for conditional expression of Cripto, i.e., the Tg:DsRed (loxP/loxP) Cripto-eGFP mice. Moreover, by using a satellite cell specific Cre-driver line we investigated the biological effect of Cripto overexpression in vivo, and provided evidence that overexpression of Cripto in the adult satellite cell compartment promotes myogenic commitment and differentiation, and enhances early regeneration in a mouse model of acute injury.

  13. Android phones for dummies

    CERN Document Server

    Gookin, Dan

    2014-01-01

    A colorful guide to make your Android phone do your bidding The popularity of Android phones is simply exploding, so it's a perfect time for popular For Dummies author Dan Gookin to update his bestselling guide to all things Android phones. From setup and configuration to taking advantage of the latest amazing Android features, this practical resource is designed to make new Android users comfortable and to help veterans get the most out of their Android phone. Covering features that are common to the most popular Android phones, this book walks you through the basics of making calls, using

  14. Comparative studies of perceived vibration strength for commercial mobile phones.

    Science.gov (United States)

    Lee, Heow Pueh; Lim, Siak Piang

    2014-05-01

    A mobile phone, also known as cell phone or hand phone, is among the most popular electrical devices used by people all over the world. The present study examines the vibration perception of mobile phones by co-relating the relevant design parameters such as excitation frequency, and size and mass of mobile phones to the vibration perception survey by volunteers. Five popular commercially available mobile phone models were tested. The main findings for the perception surveys were that higher vibration frequency and amplitude of the peak acceleration would result in stronger vibration perception of the mobile phones. A larger contact surface area with the palms and figures, higher peak acceleration and the associated larger peak inertia force may be the main factors for the relatively higher vibration perception. The future design for the vibration alert of the mobile phones is likely to follow this trend.

  15. Function of Membrane-Associated Proteoglycans in the Regulation of Satellite Cell Growth.

    Science.gov (United States)

    Song, Yan

    2016-01-01

    Muscle growth can be divided into embryonic and postnatal periods. During the embryonic period, mesenchymal stem cells proliferate and differentiate to form muscle fibers. Postnatal muscle growth (hypertrophy) is characterized by the enlargement of existing muscle fiber size. Satellite cells (also known as adult myoblasts) are responsible for hypertrophy. The activity of satellite cells can be regulated by their extracellular matrix (ECM). The ECM is composed of collagens, proteoglycans, non-collagenous glycoproteins, cytokines and growth factors. Proteoglycans contain a central core protein with covalently attached glycosaminoglycans (GAGs: chondroitin sulfate, keratan sulfate, dermatan sulfate, and heparan sulfate) and N- or O-linked glycosylation chains. Membrane-associated proteoglycans attach to the cell membrane either through a glycosylphosphatidylinositol anchor or transmembrane domain. The GAGs can bind proteins including cytokines and growth factors. Both cytokines and growth factors play important roles in regulating satellite cell growth and development. Cytokines are generally associated with immune cells. However, cytokines can also affect muscle cell development. For instance, interleukin-6, tumor necrosis factor-α, and leukemia inhibitory factor have been reported to affect the proliferation and differentiation of satellite cells and myoblasts. Growth factors are potent stimulators or inhibitors of satellite cell proliferation and differentiation. The proper function of some cytokines and growth factors requires an interaction with the cell membrane-associated proteoglycans to enhance the affinity to bind to their primary receptors to initiate downstream signal transduction. This chapter is focused on the interaction of membrane-associated proteoglycans with cytokines and growth factors, and their role in satellite cell growth and development.

  16. Proton irradiation effects of amorphous silicon solar cell for solar power satellite

    Energy Technology Data Exchange (ETDEWEB)

    Morita, Yousuke; Oshima, Takeshi [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment; Sasaki, Susumu; Kuroda, Hideo; Ushirokawa, Akio

    1997-03-01

    Flexible amorphous silicon(fa-Si) solar cell module, a thin film type, is regarded as a realistic power generator for solar power satellite. The radiation resistance of fa-Si cells was investigated by the irradiations of 3,4 and 10 MeV protons. The hydrogen gas treatment of the irradiated fa-Si cells was also studied. The fa-Si cell shows high radiation resistance for proton irradiations, compared with a crystalline silicon solar cell. (author)

  17. Temperature effect on proliferation and differentiation of satellite cells from turkeys with different growth rates.

    Science.gov (United States)

    Clark, D L; Coy, C S; Strasburg, G M; Reed, K M; Velleman, S G

    2016-04-01

    Poultry selected for growth have an inefficient thermoregulatory system and are more sensitive to temperature extremes. Satellite cells are precursors to skeletal muscle and mediate all posthatch muscle growth. Their physiological functions are affected by temperature. The objective of the current study was to determine how temperature affects satellite cells isolated from the pectoralis major (p. major) muscle (breast muscle) of turkeys selected for increased 16 wk body weight (F line) in comparison to a randombred control line (RBC2) from which the F line originated. Pectoralis major muscle satellite cells were thermally challenged by culturing between 33°C and 43°C to analyze the effects of cold and heat on proliferation and differentiation as compared to control temperature of 38°C. Expression levels of myogenic regulatory factors: myogenic differentiation factor 1 (MYOD1) and myogenin (MYOG) were quantified by quantitative polymerase chain reaction (qPCR). At all sampling times, proliferation increased at a linear rate across temperature in both the RBC2 and F lines. Differentiation also increased at a linear rate across temperature from 33 to 41°C at all sampling times in both the F and RBC2 lines. Satellite cells isolated from F line turkeys were more sensitive to both hot and cold temperatures as proliferation and differentiation increased to a greater extent across temperature (33 to 43°C) when compared with the RBC2 line. Expression of MYOD1 and MYOG increased as temperatures increased from 33 to 41°C at all sampling times in both the F and RBC2 lines. These results demonstrate that satellite cell function is sensitive to both cold and hot temperatures and p. major muscle satellite cells from F line turkeys are more sensitive to temperature extremes than RBC2 satellite cells.

  18. Sphingosine-1-phosphate mediates epidermal growth factor-induced muscle satellite cell activation

    Energy Technology Data Exchange (ETDEWEB)

    Nagata, Yosuke, E-mail: cynagata@mail.ecc.u-tokyo.ac.jp; Ohashi, Kazuya; Wada, Eiji; Yuasa, Yuki; Shiozuka, Masataka; Nonomura, Yoshiaki; Matsuda, Ryoichi

    2014-08-01

    Skeletal muscle can regenerate repeatedly due to the presence of resident stem cells, called satellite cells. Because satellite cells are usually quiescent, they must be activated before participating in muscle regeneration in response to stimuli such as injury, overloading, and stretch. Although satellite cell activation is a crucial step in muscle regeneration, little is known of the molecular mechanisms controlling this process. Recent work showed that the bioactive lipid sphingosine-1-phosphate (S1P) plays crucial roles in the activation, proliferation, and differentiation of muscle satellite cells. We investigated the role of growth factors in S1P-mediated satellite cell activation. We found that epidermal growth factor (EGF) in combination with insulin induced proliferation of quiescent undifferentiated mouse myoblast C2C12 cells, which are also known as reserve cells, in serum-free conditions. Sphingosine kinase activity increased when reserve cells were stimulated with EGF. Treatment of reserve cells with the D-erythro-N,N-dimethylsphingosine, Sphingosine Kinase Inhibitor, or siRNA duplexes specific for sphingosine kinase 1, suppressed EGF-induced C2C12 activation. We also present the evidence showing the S1P receptor S1P2 is involved in EGF-induced reserve cell activation. Moreover, we demonstrated a combination of insulin and EGF promoted activation of satellite cells on single myofibers in a manner dependent on SPHK and S1P2. Taken together, our observations show that EGF-induced satellite cell activation is mediated by S1P and its receptor. - Highlights: • EGF in combination with insulin induces proliferation of quiescent C2C12 cells. • Sphingosine kinase activity increases when reserve cells are stimulated with EGF. • EGF-induced activation of reserve cells is dependent on sphingosine kinase and ERK. • The S1P receptor S1P2 is involved in EGF-induced reserve cell activation. • EGF-induced reserve cell activation is mediated by S1P and its

  19. Effect of Mobile Phone Usage Time on Total Antioxidant Capacity of Saliva and Salivary Immunoglobulin A

    OpenAIRE

    Fateme Arbabi-Kalati; Saeedeh Salimi; Ali Vaziry-Rabiee; Mohammad Noraeei

    2014-01-01

    Abstract Background Nowadays mobile phone is very popular, causing concern about the effect it has on people’s health. Parotid salivary glands are in close contact to cell phone while talking with the phone and the possibility of being affected by them. Limited studies have evaluated the effect of cell phone use on the secretions of these glands; so this study was designed to investigate the effects of duration of mobile phone use on the total antioxidant capacity of saliva. Methods Unstimula...

  20. Cellular Phone Towers, towers, various type of towers used for cell phone and communication purposes., Published in 2010, 1:2400 (1in=200ft) scale, Glynn County Board of Commissioners.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Field Survey/GPS information as of 2010. It is described...

  1. Influence of skeletal muscle satellite cells implanted into infarcted myocardium on remnant myocyte volumes

    Institute of Scientific and Technical Information of China (English)

    钟竑; 朱洪生; 卫洪超; 张臻

    2003-01-01

    Objective To study the effects of skeletal muscle satellite cells implanted into infarcted myocardium on the volume of remnant myocytes.Methods Thirty-six adult mongrel canines were divided randomly into implantation group and control group. In the implantation group, skeletal muscle satellite cells taken from the gluteus maximus muscles of the dogs were cultured, proliferated and labeled with 4', 6-diamidino-2-phenylindone (DAPI) in vitro. In both groups, a model of acute myocardial infarction was established in every dog. In the implantation group, each dog was injected with M199 solution containing autologous skeletal muscle satellite cells. The dogs in the control group received M199 solution without skeletal muscle satellite cells. The dogs of both groups were killed 2, 4 and 8 weeks after implantation (six dogs in a separate group each time). Both infarcted myocardium and normal myocytes distal from the infracted regions isolated were observed under optical and fluorescent microscope. Their volumes were determined using a confocal microscopy image analysis system and analyzed using SAS. A P<0.05 was considered significant.Results A portion of the implanted cells differentiated into muscle fiber with striations and were connected with intercalated discs. Cross-sectional area and cell volume were increased in normal myocardium. Hypertrophy of remnant myocytes in the infarcted site after skeletal muscle cell implantation was much more evident than in the control group. Cross-sectional area, cell area and cell volume differed significantly from those of the control group (P< 0.05). Hypertrophy of the cells occurred predominantly in terms of width and thickness, whereas cell length remained unchanged. Conclusion Skeletal muscle satellite cells implanted into infarct myocardium, could induce the hypertrophy of remnant myocyte cells in the infarcted site and could also aid in the recovery of the contractile force of the infarcted myocardium.

  2. Comparison of biological effects between continuous and intermittent exposure to GSM-900-MHz mobile phone radiation: Detection of apoptotic cell-death features.

    Science.gov (United States)

    Chavdoula, Evangelia D; Panagopoulos, Dimitris J; Margaritis, Lukas H

    2010-07-19

    In the present study we used a 6-min daily exposure of dipteran flies, Drosophila melanogaster, to GSM-900MHz (Global System for Mobile Telecommunications) mobile phone electromagnetic radiation (EMR), to compare the effects between the continuous and four different intermittent exposures of 6min total duration, and also to test whether intermittent exposure provides any cumulative effects on the insect's reproductive capacity as well as on the induction of apoptotic cell death. According to our previous experiments, a 6-min continuous exposure per day for 5 days to GSM-900MHz and DCS-1800MHz (Digital Cellular System) mobile phone radiation, brought about a large decrease in the insect's reproductive capacity, as defined by the number of F(1) pupae. This decrease was found to be non-thermal and correlated with an increased percentage of induced fragmented DNA in the egg chambers' cells at early- and mid-oogenesis. In the present experiments we show that intermittent exposure also decreases the reproductive capacity and alters the actin-cytoskeleton network of the egg chambers, another known aspect of cell death that was not investigated in previous experiments, and that the effect is also due to DNA fragmentation. Intermittent exposures with 10-min intervals between exposure sessions proved to be almost equally effective as continuous exposure of the same total duration, whereas longer intervals between the exposures seemed to allow the organism the time required to recover and partly overcome the above-mentioned effects of the GSM exposure.

  3. Enhanced satellite cell proliferation with resistance training in elderly men and women

    DEFF Research Database (Denmark)

    Mackey, Abigail; Esmarck, B; Kadi, F

    2007-01-01

    In addition to the well-documented loss of muscle mass and strength associated with aging, there is evidence for the attenuating effects of aging on the number of satellite cells in human skeletal muscle. The aim of this study was to investigate the response of satellite cells in elderly men...... and women to 12 weeks of resistance training. Biopsies were collected from the m. vastus lateralis of 13 healthy elderly men and 16 healthy elderly women (mean age 76+/-SD 3 years) before and after the training period. Satellite cells were visualized by immunohistochemical staining of muscle cross......-sections with a monoclonal antibody against neural cell adhesion molecule (NCAM) and counterstaining with Mayer's hematoxylin. Compared with the pre-training values, there was a significant increase (Pcells per fiber post-training in males (from 0.11+/-0.03 to 0...

  4. THE ROLE OF SATELLITE CELLS IN CRUSH INJURY OF RAT SKELETON MUSCLE

    Directory of Open Access Journals (Sweden)

    DilekBURUKOĞLU

    2013-02-01

    Full Text Available The crush type of injury in rat skeletal muscle is often used in tissue degeneration and regeneration. After crush injury muscle tissue begins to regenerate. In this process, it is accepted that satellite cells play an important role which are very sensitive to muscle injury. The aim of this microscopic study was to examine role of satellite cells in muscle regeneration in crush injury. This research was done the department of Histology&Embryology in Eskişehir Osmangazi University in 2008. Ethic approval of this study has been received. During the study, the whole essential and ethics conditionshave been done. In the study 36 Spraque-Dawley rats were used. The rats were separated into 5 groups as test and control groups. Crush type of injury has been applied on muscles of right hind extremitiesof testing group rats by applying 3.5 kg of weight for 6 hours. In according to testing periods rats were anaesthetized intraperitoneally with ketamine 30mg/kg + xylazine 10mg/kg and sacrificied 3, 7, 14 and 21-day intervals. After crush injury, increased satellite cells were particularly observed on day 7. Alsosignificant increased of satellite cells and regenerated myofibrils were detected on day 14. However, satellite cells were seen on day-21 were similar to control group. In crush injuries, number of satellitecells were markedly increased and actively involved into regeneration process of the skeleton muscle.

  5. Characterisation of equine satellite cell transcriptomic profile response to β-hydroxy-β-methylbutyrate (HMB).

    Science.gov (United States)

    Szcześniak, Katarzyna A; Ciecierska, Anna; Ostaszewski, Piotr; Sadkowski, Tomasz

    2016-10-01

    β-Hydroxy-β-methylbutyrate (HMB) is a popular ergogenic aid used by human athletes and as a supplement to sport horses, because of its ability to aid muscle recovery, improve performance and body composition. Recent findings suggest that HMB may stimulate satellite cells and affect expressions of genes regulating skeletal muscle cell growth. Despite the scientific data showing benefits of HMB supplementation in horses, no previous study has explained the mechanism of action of HMB in this species. The aim of this study was to reveal the molecular background of HMB action on equine skeletal muscle by investigating the transcriptomic profile changes induced by HMB in equine satellite cells in vitro. Upon isolation from the semitendinosus muscle, equine satellite cells were cultured until the 2nd day of differentiation. Differentiating cells were incubated with HMB for 24 h. Total cellular RNA was isolated, amplified, labelled and hybridised to microarray slides. Microarray data validation was performed with real-time quantitative PCR. HMB induced differential expressions of 361 genes. Functional analysis revealed that the main biological processes influenced by HMB in equine satellite cells were related to muscle organ development, protein metabolism, energy homoeostasis and lipid metabolism. In conclusion, this study demonstrated for the first time that HMB has the potential to influence equine satellite cells by controlling global gene expression. Genes and biological processes targeted by HMB in equine satellite cells may support HMB utility in improving growth and regeneration of equine skeletal muscle; however, the overall role of HMB in horses remains equivocal and requires further proteomic, biochemical and pharmacokinetic studies.

  6. Restricted maternal nutrition alters myogenic regulatory factor expression in satellite cells of ovine offspring.

    Science.gov (United States)

    Raja, J S; Hoffman, M L; Govoni, K E; Zinn, S A; Reed, S A

    2016-07-01

    Poor maternal nutrition inhibits muscle development and postnatal muscle growth. Satellite cells are myogenic precursor cells that contribute to postnatal muscle growth, and their activity can be evaluated by the expression of several transcription factors. Paired-box (Pax)7 is expressed in quiescent and active satellite cells. MyoD is expressed in activated and proliferating satellite cells and myogenin is expressed in terminally differentiating cells. Disruption in the expression pattern or timing of expression of myogenic regulatory factors negatively affects muscle development and growth. We hypothesized that poor maternal nutrition during gestation would alter the in vitro temporal expression of MyoD and myogenin in satellite cells from offspring at birth and 3 months of age. Ewes were fed 100% or 60% of NRC requirements from day 31±1.3 of gestation. Lambs from control-fed (CON) or restricted-fed (RES) ewes were euthanized within 24 h of birth (birth; n=5) or were fed a control diet until 3 months of age (n=5). Satellite cells isolated from the semitendinosus muscle were used for gene expression analysis or cultured for 24, 48 or 72 h and immunostained for Pax7, MyoD or myogenin. Fusion index was calculated from a subset of cells allowed to differentiate. Compared with CON, temporal expression of MyoD and myogenin was altered in cultured satellite cells isolated from RES lambs at birth. The percent of cells expressing MyoD was greater in RES than CON (P=0.03) after 24 h in culture. After 48 h of culture, there was a greater percent of cells expressing myogenin in RES compared with CON (P0.05). In satellite cells from RES lambs at 3 months of age, the percent of cells expressing MyoD and myogenin were greater than CON after 72 h in culture (Psatellite cells of the offspring, which may reduce the pool of myoblasts, decrease myoblast fusion and contribute to the poor postnatal muscle growth previously observed in these animals.

  7. Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats

    Directory of Open Access Journals (Sweden)

    Mokarram P.

    2017-03-01

    Full Text Available Background: Over the past several years, the rapidly increasing use of mobile phones has raised global concerns about the biological effects of exposure to radiofrequency (RF radiation. Numerous studies have shown that exposure to electromagnetic fields (EMFs can be associated with effects on the nervous, endocrine, immune, cardiovascular, hematopoietic and ocular systems. In spite of genetic diversity, the onset and progression of cancer can be controlled by epigenetic mechanisms such as gene promoter methylation. There are extensive studies on the epigenetic changes of the tumor suppressor genes as well as the identification of methylation biomarkers in colorectal cancer. Some studies have revealed that genetic changes can be induced by exposure to RF radiation. However, whether or not RF radiation is capable of inducing epigenetic alteration has not been clarified yet. To date, no study has been conducted on the effect of radiation on epigenetic alterations in colorectal cancer (CRC. Several studies have also shown that methylation of estrogen receptor α (ERα, MYOD, MGMT, SFRP2 and P16 play an important role in CRC. It can be hypothesized that RF exposure can be a reason for the high incidence of CRC in Iran. This study aimed to investigate whether epigenetic pattern of ERα is susceptible to RF radiation and if RF radiation can induce radioadaptive response as epigenetic changes after receiving the challenge dose (γ-ray. Material and Method: 40 male Sprague-Dawley rats were divided into 4 equal groups (Group I: exposure to RF radiation of a GSM cell phone for 4 hours and sacrificed after 24 hours; Group II: RF exposure for 4 hours, exposure to Co-60 gamma radiation (3 Gy after 24 hours and sacrificed after 72 hrs; Group III: only 3Gy gamma radiation; Group 4: control group. DNA from colon tissues was extracted to evaluate the methylation status by methylation specific PCR. Results: Our finding showed that exposure to GSM cell phone RF

  8. Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats.

    Science.gov (United States)

    Mokarram, P; Sheikhi, M; Mortazavi, S M J; Saeb, S; Shokrpour, N

    2017-03-01

    Over the past several years, the rapidly increasing use of mobile phones has raised global concerns about the biological effects of exposure to radiofrequency (RF) radiation. Numerous studies have shown that exposure to electromagnetic fields (EMFs) can be associated with effects on the nervous, endocrine, immune, cardiovascular, hematopoietic and ocular systems. In spite of genetic diversity, the onset and progression of cancer can be controlled by epigenetic mechanisms such as gene promoter methylation. There are extensive studies on the epigenetic changes of the tumor suppressor genes as well as the identification of methylation biomarkers in colorectal cancer. Some studies have revealed that genetic changes can be induced by exposure to RF radiation. However, whether or not RF radiation is capable of inducing epigenetic alteration has not been clarified yet. To date, no study has been conducted on the effect of radiation on epigenetic alterations in colorectal cancer (CRC). Several studies have also shown that methylation of estrogen receptor α (ERα), MYOD, MGMT, SFRP2 and P16 play an important role in CRC. It can be hypothesized that RF exposure can be a reason for the high incidence of CRC in Iran. This study aimed to investigate whether epigenetic pattern of ERα is susceptible to RF radiation and if RF radiation can induce radioadaptive response as epigenetic changes after receiving the challenge dose (γ-ray). 40 male Sprague-Dawley rats were divided into 4 equal groups (Group I: exposure to RF radiation of a GSM cell phone for 4 hours and sacrificed after 24 hours; Group II: RF exposure for 4 hours, exposure to Co-60 gamma radiation (3 Gy) after 24 hours and sacrificed after 72 hrs; Group III: only 3Gy gamma radiation; Group 4: control group). DNA from colon tissues was extracted to evaluate the methylation status by methylation specific PCR. Our finding showed that exposure to GSM cell phone RF radiation was capable of altering the pattern of ERα gene

  9. IMPROVING METHODOLOGICAL STRATEGIES FOR SATELLITE CELLS COUNTING IN HUMAN MUSCLE DURING AGEING

    Directory of Open Access Journals (Sweden)

    Špela Sajko

    2011-05-01

    Full Text Available Stereological methods, based on the optical disector principle and fluorescent staining, were developed for estimating frequency of satellite cells in skeletal muscles. The parameter NL(sc, fib (number of satellite cells per fibre length was compared with the parameter NN(sc, nucl (the percentage of satellite cell nuclei in all muscle nuclei, most often published in the literature, by applying unbiased sampling and counting procedures and using a confocal microscope. The methods were tested in autopsy samples of four young vs. four old human vastus lateralis muscles. Both parameters NL(sc, fib and NN(sc, nucl declined during ageing. However, it appears that the two parameters cannot be substituted one by the other because the number of nuclei per fibre length tends to be increased during aging. Using the introduced methods, it is more straightforward to estimate NL(sc, fib than NN(sc, nucl.

  10. Pericytes in the myovascular niche promote post-natal myofiber growth and satellite cell quiescence.

    Science.gov (United States)

    Kostallari, Enis; Baba-Amer, Yasmine; Alonso-Martin, Sonia; Ngoh, Pamela; Relaix, Frederic; Lafuste, Peggy; Gherardi, Romain K

    2015-04-01

    The satellite cells, which serve as adult muscle stem cells, are both located beneath myofiber basement membranes and closely associated with capillary endothelial cells. We observed that 90% of capillaries were associated with pericytes in adult mouse and human muscle. During post-natal growth, newly formed vessels with their neuroglial 2 proteoglycan (NG2)-positive pericytes became progressively associated with the post-natal muscle stem cells, as myofibers increased in size and satellite cells entered into quiescence. In vitro, human muscle-derived pericytes promoted myogenic cell differentiation through insulin-like growth factor 1 (IGF1) and myogenic cell quiescence through angiopoietin 1 (ANGPT1). Diphtheria toxin-induced ablation of muscle pericytes in growing mice led both to myofiber hypotrophy and to impaired establishment of stem cells quiescence. Similar effects were observed following conditional in vivo deletion of pericyte Igf1 and Angpt1 genes, respectively. Our data therefore demonstrate that, by promoting post-natal myogenesis and stem cell quiescence, pericytes play a key role in the microvascular niche of satellite cells. © 2015. Published by The Company of Biologists Ltd.

  11. Effect of Cell Phone Radiation (940 MHz on the Learning and Memory of Balb/c mice

    Directory of Open Access Journals (Sweden)

    J Baharara

    2009-07-01

    After behavioral studies, fetal heads were collected, fixed in 10% paraformaldehyde and paraffine embedded. Results: Microwave-exposed mice were slower than sham-exposed, and cage control in swim speed (WM. Error Analyses rates reveal significant exposure effect in RAM and MWM. However, in this study the exposed group had not significantly lost their hippocampal CA3 neurons comparing to controls or sham exposed group. Conclusion: Increased time to locate a submerged in water maze, reference memory (entries into unbaited arms, working memory (repeated entries into baited arms, show that acute exposure to pulsed microwaves caused a deficit in spatial reference memory in the mouse. Keywords: Mobile phone, learning, memory, hippocampus

  12. iPhone Idol

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Technophiles around the world are snapping up Apple’s new iPhone. How much longer must the Chinese wait?The iPhone, a faster and more versatile version of Apple Inc.’s original touch-based mobile handset, has been a market hit since it went on

  13. THE IMPROVEMENT OF INFARCTED MYOCARDIAL CONTRACTILE FORCE AFTER AUTOLOGOUS SKELETAL MUSCLE SATELLITE CELL IMPLANTATION

    Institute of Scientific and Technical Information of China (English)

    钟竑; 朱洪生; 张臻

    2002-01-01

    Objective To study the improvement of infarcted myocardial contractile force after autologous skeletal muscle satellite cell implantation via intracoronary arterial perfusion. Methods Skeletal muscle cells were harvested from gluteus max of adult mongrel dogs and the cells were cultured and expanded before being labeled with DAPI (4, 6-diamidino-2-phenylindone). The labeled cells were then implanted into the acute myocardial infarct site via the ligated left anterior descending (LAD) coronary artery. Specimens were taken at 2nd, 4th, 8th week after myoblast implantation for histologic and contractile force evaluation, respectively. Results The satellite cells with fluorescence had been observed in the infarct site and also in papi-llary muscle with consistent oriented direction of host myocardium. A portion of the implanted cells had differen-tiated into muscle fibers. Two weeks after implantation, the myocardial contractile force showed no significant difference between the cell implant group and control group. At 4 and 8 week, the contractile force in the cell implant group was better than that in control group. Conclusion The skeletal muscle satellite cells, implanted into infarct myocardium by intracoronary arterial perfusion, could disseminate through the entire infarcted zone with myocardial regeneration and improve the contractile function of the infarcted myocardium.

  14. On the phone

    DEFF Research Database (Denmark)

    Paasch, Bettina Sletten

    In most Danish hospitals clinicians are being equipped with a mobile phone in order to improve their availability. Based on an ethnomethodological approach (Garfinkel, 1967) the present paper explores how mobile phones shape clinicians´ practices. Using Nexus Analysis (Scollon & Scollon, 2004....... The analysis shows how the mobile phone becomes part of the way clinicians choreograph body movement in interactions with patients, how they arrange their bodies and how they gesture and position themselves. It is demonstrated how the use of mobile phones can mediate the clinicians´ accomplishment of an action...... space with the patient, the boundaries of attention created by the clinicians and the trajectories of actions. The analysis further shows how the mobile phone allows for the clinicians to negotiate and co-construct their practices across space and physical materiality. It is demonstrated how the use...

  15. The Effects of Electromagnetic Fields Generated from 1800 MHz Cell Phones on Erythrocyte Rheological Parameters and Zinc Level in Rats

    Directory of Open Access Journals (Sweden)

    Ümit Divrikli

    2012-06-01

    Full Text Available Objective: The aim of this study was to investigate the effects of the electromagnetic field generated from the 1800 MHz radiofrequency radiation (EF on erythrocyte rheological parameters and erythrocyte zinc levels. Material and Methods: Twenty-four male Wistar Albino rats were randomly grouped as follows: 1 two control groups and 2 study groups: i Group A: EF exposed group (2.5 h/day for 30 days, the phone on stand-by, and ii Group B: EF exposed group (2.5 min/day for 30 days, the phone ringing in silent mode. At the end of the experimental period erythrocyte rheological parameters such as erythrocyte deformability and aggregation were determined by an ectacytometer. Erythrocyte zinc level, which affects hemorheological parameters, was also measured by atomic absorption spectrophotometer. Results: Erythrocyte deformability was decreased in both study groups but the decrease in group A was not statistically significant. Exposure to EF did not have any significant effect on erythrocyte aggregation. On the other hand, erythrocyte zinc level was significantly reduced in both study groups. Conclusion: Exposure to EF may have decreased tissue oxygenation due to reduced erythrocyte deformability. Decrease in erythrocyte zinc level may have caused the impairment in erythrocyte deformability.

  16. Changes in satellite cells in human skeletal muscle after a single bout of high intensity exercise

    DEFF Research Database (Denmark)

    Crameri, Regina M; Langberg, Henning; Magnusson, Peter

    2004-01-01

    desmin or dystrophin, were not observed, and hence did not appear to induce the expression of either N-CAM or FA1. We therefore propose that satellite cells can be induced to re-enter the cell growth cycle after a single bout of unaccustomed high intensity exercise. However, a single bout of exercise......No studies to date have reported activation of satellite cells in vivo in human muscle after a single bout of high intensity exercise. In this investigation, eight individuals performed a single bout of high intensity exercise with one leg, the contralateral leg being the control. A significant...... increase in mononuclear cells staining for the neural cell adhesion molecule (N-CAM) and fetal antigen 1 (FA1) were observed within the exercised human vastus lateralis muscle on days 4 and 8 post exercise. In addition, a significant increase in the concentration of the FA1 protein was determined...

  17. Pax3-induced expansion enables the genetic correction of dystrophic satellite cells.

    Science.gov (United States)

    Filareto, Antonio; Rinaldi, Fabrizio; Arpke, Robert W; Darabi, Radbod; Belanto, Joseph J; Toso, Erik A; Miller, Auston Z; Ervasti, James M; McIvor, R Scott; Kyba, Michael; Perlingeiro, Rita Cr

    2015-01-01

    Satellite cells (SCs) are indispensable for muscle regeneration and repair; however, due to low frequency in primary muscle and loss of engraftment potential after ex vivo expansion, their use in cell therapy is currently unfeasible. To date, an alternative to this limitation has been the transplantation of SC-derived myogenic progenitor cells (MPCs), although these do not hold the same attractive properties of stem cells, such as self-renewal and long-term regenerative potential. We develop a method to expand wild-type and dystrophic fresh isolated satellite cells using transient expression of Pax3. This approach can be combined with genetic correction of dystrophic satellite cells and utilized to promote muscle regeneration when transplanted into dystrophic mice. Here, we show that SCs from wild-type and dystrophic mice can be expanded in culture through transient expression of Pax3, and these expanded activated SCs can regenerate the muscle. We test this approach in a gene therapy model by correcting dystrophic SCs from a mouse lacking dystrophin using a Sleeping Beauty transposon carrying the human μDYSTROPHIN gene. Transplantation of these expanded corrected cells into immune-deficient, dystrophin-deficient mice generated large numbers of dystrophin-expressing myofibers and improved contractile strength. Importantly, in vitro expanded SCs engrafted the SC compartment and could regenerate muscle after secondary injury. These results demonstrate that Pax3 is able to promote the ex vivo expansion of SCs while maintaining their stem cell regenerative properties.

  18. Celulares: a emergência de um novo tipo de controle materno Cell phones: the emergence of a new king of materal control

    Directory of Open Access Journals (Sweden)

    Ana Maria Nicolaci-da-Costa

    2006-12-01

    Full Text Available Em uma pesquisa exploratória sobre o uso de celulares por jovens das camadas médias cariocas, entre 18 e 25 de idade, foi constatado que eles reclamavam muito que suas mães os controlavam ininterruptamente por meio de seus celulares. Para averiguar mais detalhadamente o que acontece entre mães e filhos dessa faixa etária, foi realizada uma segunda pesquisa. Nesta, foram entrevistadas 20 mães, também pertencentes às camadas médias cariocas, cujos filhos tinham perfil análogo ao dos jovens da primeira pesquisa. Para todas, a principal função dos celulares é abertamente a de controlar os filhos. Elas mostraram, no entanto, saber que há uma diferença entre o controle que vigorava quando eram jovens e aquele ao qual hoje submetem os filhos. Teorias contemporâneas sobre controle e vigilância de fato argumentam que houve uma substituição do controle normativo e coercitivo da modernidade pelo "ter conhecimento" do que se passa, característico da Era da Informação.An exploratory research on the use of cell phones by middle-class youngsters, ages 18 to 25, residing in Rio de Janeiro, revealed that they complained a great deal that their mothers controlled them unrelentingly by means of cell phones. To take a deeper look into what happens between mothers and children in this age group, a second investigation was carried out. Twenty middle-class mothers were interviewed, whose children's profile were analogous to that of the youngsters in the previous research. For all of the mothers, the main benefit of cell phones is to control their children. Nevertheless, they demonstrated to know that there's a difference between the control that they submit their children to from that that prevailed when they themselves were young. Contemporary control and surveillance theories, in fact, argue that the normative and coercive control of modernity has been replaced by "having knowledge" of what goes on, which is characteristic of the Information

  19. Comparison and analysis of Wuding and avian chicken skeletal muscle satellite cells

    NARCIS (Netherlands)

    Tong, H.Q.; Jiang, Z.Q.; Dou, T.F.; Li, Q.H.; Xu, Z.Q.; Liu, L.X.; Gu, D.H.; Rong, H.; Huang, Y.; Chen, X.B.; Jois, M.; Pas, te M.F.W.; Ge, C.R.; Jia, J.J.

    2016-01-01

    Chicken skeletal muscle satellite cells are located between the basement membrane and the sarcolemma of mature muscle fibers. Avian broilers have been genetically selected based on their high growth velocity and large muscle mass. The Wuding chicken is a famous local chicken in Yunnan Province th

  20. Whey protein supplementation accelerates satellite cell proliferation during recovery from eccentric exercise

    DEFF Research Database (Denmark)

    Farup, Jean; Rahbek, Stine Klejs; Knudsen, Inge Skovgaard

    2014-01-01

    Human skeletal muscle satellite cells (SCs) are essential for muscle regeneration and remodeling processes in healthy and clinical conditions involving muscle breakdown. However, the potential influence of protein supplementation on post-exercise SC regulation in human skeletal muscle has not bee...

  1. Reduced satellite cell numbers with spinal cord injury and aging in humans

    NARCIS (Netherlands)

    Verdijk, L.B.; Dirks, M.L.; Snijders, T.; Prompers, J.J.; Beelen, M.; Jonkers, R.A.; Thijssen, D.H.J.; Hopman, M.T.E.; Loon, L.J. van

    2012-01-01

    INTRODUCTION: Both sarcopenia and spinal cord injury (SCI) are characterized by the loss of skeletal muscle mass and function. Despite obvious similarities in atrophy between both models, differences in muscle fiber size and satellite cell content may exist on a muscle fiber type-specific level.

  2. Muscle atrophy reversed by growth factor activation of satellite cells in a mouse muscle atrophy model.

    Directory of Open Access Journals (Sweden)

    Simon Hauerslev

    Full Text Available Muscular dystrophies comprise a large group of inherited disorders that lead to progressive muscle wasting. We wanted to investigate if targeting satellite cells can enhance muscle regeneration and thus increase muscle mass. We treated mice with hepatocyte growth factor and leukemia inhibitory factor under three conditions: normoxia, hypoxia and during myostatin deficiency. We found that hepatocyte growth factor treatment led to activation of the Akt/mTOR/p70S6K protein synthesis pathway, up-regulation of the myognic transcription factors MyoD and myogenin, and subsequently the negative growth control factor, myostatin and atrophy markers MAFbx and MuRF1. Hypoxia-induced atrophy was partially restored by hepatocyte growth factor combined with leukemia inhibitory factor treatment. Dividing satellite cells were three-fold increased in the treatment group compared to control. Finally, we demonstrated that myostatin regulates satellite cell activation and myogenesis in vivo following treatment, consistent with previous findings in vitro. Our results suggest, not only a novel in vivo pharmacological treatment directed specifically at activating the satellite cells, but also a myostatin dependent mechanism that may contribute to the progressive muscle wasting seen in severely affected patients with muscular dystrophy and significant on-going regeneration. This treatment could potentially be applied to many conditions that feature muscle wasting to increase muscle bulk and strength.

  3. Cellular Phone Towers, Cell towers developed for Appraiser's Department in 2003. Location was based upon parcel centroids, and corrected to orthophotography. Probably includes towers other than cell towers (uncertain). Not published., Published in 2003, 1:1200 (1in=100ft) scale, Sedgwick County, Kansas.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:1200 (1in=100ft) scale, was produced all or in part from Other information as of 2003. It is described as 'Cell...

  4. Cellular Phone Towers, File name = CELLTOWERS Contains point file of cell towers and an inclomplete poly cadastral layer of properties with cell towers. http://www.harfordcountymd.gov/gis/Index.cfm, Published in 2011, 1:1200 (1in=100ft) scale, Harford County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Cellular Phone Towers dataset current as of 2011. File name = CELLTOWERS Contains point file of cell towers and an inclomplete poly cadastral layer of properties...

  5. Cellular Phone Towers, Cell towers developed for Appraiser's Department in 2003. Location was based upon parcel centroids, and corrected to orthophotography. Probably includes towers other than cell towers (uncertain). Not published., Published in 2003, 1:1200 (1in=100ft) scale, Sedgwick County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Cellular Phone Towers dataset current as of 2003. Cell towers developed for Appraiser's Department in 2003. Location was based upon parcel centroids, and corrected...

  6. Alkaline regenerative fuel cell energy storage system for manned orbital satellites

    Science.gov (United States)

    Martin, R. E.; Gitlow, B.; Sheibley, D. W.

    1982-01-01

    It is pointed out that the alkaline regenerative fuel cell system represents a highly efficient, lightweight, reliable approach for providing energy storage in an orbiting satellite. In addition to its energy storage function, the system can supply hydrogen and oxygen for attitude control of the satellite and for life support. A summary is presented of the results to date obtained in connection with the NASA-sponsored fuel cell technology advancement program, giving particular attention to the requirements of the alkaline regenerative fuel cell and the low-earth mission. Attention is given to system design guidelines, weight considerations, gold-platinum cathode cell performance, matrix development, the electrolyte reservoir plate, and the cyclical load profile tests.

  7. Cycle training modulates satellite cell and transcriptional responses to a bout of resistance exercise.

    Science.gov (United States)

    Murach, Kevin A; Walton, R Grace; Fry, Christopher S; Michaelis, Sami L; Groshong, Jason S; Finlin, Brian S; Kern, Philip A; Peterson, Charlotte A

    2016-09-01

    This investigation evaluated whether moderate-intensity cycle ergometer training affects satellite cell and molecular responses to acute maximal concentric/eccentric resistance exercise in middle-aged women. Baseline and 72 h postresistance exercise vastus lateralis biopsies were obtained from seven healthy middle-aged women (56 ± 5 years, BMI 26 ± 1, VO2max 27 ± 4) before and after 12 weeks of cycle training. Myosin heavy chain (MyHC) I- and II-associated satellite cell density and cross-sectional area was determined via immunohistochemistry. Expression of 93 genes representative of the muscle-remodeling environment was also measured via NanoString. Overall fiber size increased ~20% with cycle training (P = 0.052). MyHC I satellite cell density increased 29% in response to acute resistance exercise before endurance training and 50% with endurance training (P training, MyHC I satellite cell density decreased by 13% in response to acute resistance exercise (acute resistance × training interaction, P trained state in response to resistance exercise. Similar satellite cell and gene expression response patterns indicate coordinated regulation of the muscle environment to promote adaptation. Moderate-intensity endurance cycle training modulates the response to acute resistance exercise, potentially conditioning the muscle for more intense concentric/eccentric activity. These results suggest that cycle training is an effective endurance exercise modality for promoting growth in middle-aged women, who are susceptible to muscle mass loss with progressing age.

  8. Brain and muscle Arnt-like 1 promotes skeletal muscle regeneration through satellite cell expansion

    Energy Technology Data Exchange (ETDEWEB)

    Chatterjee, Somik [Center for Diabetes Research, Department of Medicine, Houston Methodist Research Institute, Houston, TX 77030 (United States); Yin, Hongshan [Center for Diabetes Research, Department of Medicine, Houston Methodist Research Institute, Houston, TX 77030 (United States); Department of Cardiovascular Medicine, Third Affiliated Hospital, Hebei Medical University, Shijiazhuang 050051, Hebei (China); Nam, Deokhwa [Center for Diabetes Research, Department of Medicine, Houston Methodist Research Institute, Houston, TX 77030 (United States); Li, Yong [Department of Pediatric Surgery, Center for Stem Cell Research and Regenerative Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030 (United States); Ma, Ke, E-mail: kma@houstonmethodist.org [Center for Diabetes Research, Department of Medicine, Houston Methodist Research Institute, Houston, TX 77030 (United States)

    2015-02-01

    Circadian clock is an evolutionarily conserved timing mechanism governing diverse biological processes and the skeletal muscle possesses intrinsic functional clocks. Interestingly, although the essential clock transcription activator, Brain and muscle Arnt-like 1 (Bmal1), participates in maintenance of muscle mass, little is known regarding its role in muscle growth and repair. In this report, we investigate the in vivo function of Bmal1 in skeletal muscle regeneration using two muscle injury models. Bmal1 is highly up-regulated by cardiotoxin injury, and its genetic ablation significantly impairs regeneration with markedly suppressed new myofiber formation and attenuated myogenic induction. A similarly defective regenerative response is observed in Bmal1-null mice as compared to wild-type controls upon freeze injury. Lack of satellite cell expansion accounts for the regeneration defect, as Bmal1{sup −/−} mice display significantly lower satellite cell number with nearly abolished induction of the satellite cell marker, Pax7. Furthermore, satellite cell-derived primary myoblasts devoid of Bmal1 display reduced growth and proliferation ex vivo. Collectively, our results demonstrate, for the first time, that Bmal1 is an integral component of the pro-myogenic response that is required for muscle repair. This mechanism may underlie its role in preserving adult muscle mass and could be targeted therapeutically to prevent muscle-wasting diseases. - Highlights: • Bmal1 is highly inducible by muscle injury and myogenic stimuli. • Genetic ablation of Bmal1 significantly impairs muscle regeneration. • Bmal1 promotes satellite cell expansion during muscle regeneration. • Bmal1-deficient primary myoblasts display attenuated growth and proliferation.

  9. Corporate Smart Phones

    DEFF Research Database (Denmark)

    Cavazotte, Flávia; Heloisa Lemos, Ana; Villadsen, Kaspar

    2014-01-01

    This article explores how the adoption of company sponsored smart phones inflicts upon the lives of professionals. Drawing upon qualitative interviews at a law firm in Brazil, the experiences of new smart phone users are reported upon in detail. Increased accessibility, accuracy and speed...... that negatively affected their private spheres, yet many of them paradoxically requested more efficient smart phone connectivity. The article focuses on the justifications, the different narrative strategies, employed by professionals for their conscious engagement in escalating work connectivity. It is suggested...

  10. 手机行车记录仪的开发%Development of Cell-Phone-Type Vehicle Traveling Data Recorder

    Institute of Scientific and Technical Information of China (English)

    苏维嘉; 殷志富

    2011-01-01

    设计了一种新型的手机式汽车行驶记录仪.在数据处理、信息显示以及数据存储方面,利用手机本身的处理器、LCD和SD卡替代了传统行车记录仪的相应功能部件.在数据传输方面,采用手机蓝牙与数据采集装置进行信息交换、命令传递,实现无线通讯.蓝牙具有特殊、普通两组服务,区分了系统用户和普通用户的访问权限.整个系统具有显示、车辆行驶参数记录与分析、数据保存与回放功能,实现了行车系统的便携化和无线化.%A new cell-phone-type vehicle traveling data recorder is designed. In the aspect of data processing,information display and data storage, it uses cell phone's processor, LCD and SD card instead of traditional vehicle traveling data recorder's corresponding components. In the aspect of data transmission, it uses Blueteeth to exchange information and order with the data acquisition equipment. It achieves wireless communication. Bluetooth has a special service and an ordinary service. It distinguishes accessing power between system user and guest user. The system could display, record and analyze parameters of vehicles, save and playback data of acquisition. It realizes. It makes the vehicle traveling data recorder portable and wireless.

  11. Do cell phones, iPods/MP3 players, siblings and friends matter? Predictors of child body mass in a U.S. Southern Border City Middle School.

    Science.gov (United States)

    Ynalvez, Marcus Antonius; Ynalvez, Ruby; Torregosa, Marivic; Palacios, Horacio; Kilburn, John

    2012-01-01

    This study examines the association of children's (i) micro-social environment, specifically siblings [kin-friends] and friends from school and neighborhood [non-kin-friends], and (ii) ownership of information and communication technologies (ICT), specifically cell phones and iPod/MP3 players, with body mass index percentile (BMIp). Fifty-five randomly selected 6th graders with a mean age of 12 years, stratified by gender (23 boys and 32 girls), from a Texas middle school located in a city along the U.S. southern border. The linear regression of BMIp on number of siblings and of non-kin-friends, and ownership of cell phone and of iPod/MP3 player was examined using two models: M1 was based on the manual selection of predictors from a pool of potential predictors. M2 was derived from the predictors specified in M1 using backward elimination technique. Because sample size was small, the significance of regression coefficients was evaluated using robust standard errors to calculate t-values. Data for predictors were obtained through a survey. Height and weight were obtained through actual anthropometric measurements. BMIp was calculated using the on-line BMI calculator of the Center for Disease Control and Prevention. Findings reveal that children's social environment and ICT ownership predict BMIp; specifically, number of siblings (M2: β = -0.34, p-value value personal technical devices (that encourage solitary, and oftentimes sedentary, activities) in predicting child body mass. © 2012 Asian Oceanian Association for the Study of Obesity . Published by Elsevier Ltd. All rights reserved.

  12. [Effect of Guilingji Capsule on the fertility, liver functions, and serum LDH of male SD rats exposed by 900 mhz cell phone].

    Science.gov (United States)

    Ma, Hui-Rong; Li, Yuan-Yuan; Luo, Ya-Ping; Ma, Xue-Lian; Gong, Zhi-Qiang

    2014-04-01

    To observe the effect of Guilingji Capsule (GC) on the fertility, liver functions, and serum lactate dehydrogenase (LDH) of adult male SD rats exposed by 900 MHz cell phone. Totally 18 adult male SD rats and 36 adult female rats in child-bearing period were selected and randomly divided into three groups according to weight equilibrium principle, i.e., the normal group, the radiated group, and the GC group, 6 males and 12 females in each group. Male rats in the normal group and all female rats were not radiated. Male rats in the radiated group and the GC group received radiation for 4 h per day, lasting for 18 successive days. Rats in the GC group received GC suspension at the daily dose of 0. 15 g/kg by gastrogavage at the same time. Equal volume of normal saline was administrated to other male rats. Then male rats were mated with corresponding female rats from the 14th radiation night to the 18th radiation night in the ratio of 1:2. Male rats were killed following on the next morning of ending the radiation. Female rats were normally fed and then killed before delivery. The pregnant outcomes of female rats in responding groups (the rates of pregnancy and the number of death fetus, birth weight, body length, and tail length) were observed and compared. Serum alanine aminotransferase (ALT), aspartate transferase (AST), AST/ALT, and LDH levels of the male rats were detected by colorimetry. Histological and morphological changes of liver were observed by HE staining. Compared with the normal group, the pregnancy rates of female rats decreased and the number of death fetus increased, the serum LDH level obviously increased in the radiated group (P LDH decreased in the GC group (P LDH level increased by exposure toy GSM 900 MHz cell phone. GC could prevent and treat the aforesaid lesion. But there was no statistical difference in serum ALT or AST levels.

  13. Mobile Phones: Potential Sources of Nickel and Cobalt Exposure for Metal Allergic Patients.

    Science.gov (United States)

    Aquino, Marcella; Mucci, Tania; Chong, Melanie; Lorton, Mark Davis; Fonacier, Luz

    2013-12-01

    The use of cellular phones has risen exponentially with over 300 million subscribers. Nickel has been detected in cell phones and reports of contact dermatitis attributable to metals are present in the literature. We determined nickel and cobalt content in popular cell phones in the United States. Adults (>18 years) who owned a flip phone, Blackberry(®), or iPhone(®) were eligible. Seventy-two cell phones were tested using SmartPractice's(®) commercially available nickel and cobalt spot tests. Test areas included buttons, keypad, speakers, camera, and metal panels. Of the 72 cell phones tested, no iPhones or Droids(®) tested positive for nickel or cobalt. About 29.4% of Blackberrys [95% confidence interval (CI), 13%-53%] tested positive for nickel; none were positive for cobalt. About 90.5% of flip phones (95% CI, 70%-99%) tested positive for nickel and 52.4% of flip phones (95% CI, 32%-72%) tested positive for cobalt. Our study indicates that nickel and cobalt are present in popular cell phones. Patients with known nickel or cobalt allergy may consider their cellular phones as a potential source of exposure. Further studies are needed to examine whether there is a direct association with metal content in cell phones and the manifestation of metal allergy.

  14. iPhones and Smartphones

    Directory of Open Access Journals (Sweden)

    Kevin YE

    2009-10-01

    Full Text Available Long utilized in European and Asian countries, fast ―next generation‖ cell phonenetworks and mobile data streams have only recently begun to make deep inroads inthe United States, and companies are scrambling to write content, tools, and newapplets (―apps‖ for these users. The iPhone has become a juggernaut in the UnitedStates, with 13 million units sold in 2008 (a 245% increase over 2007 and a further 45million units expected in 2009 (Elmer-DeWitt, 2009. While iPhone still lags Nokia andRIM internationally, the overall trend toward mobile computing becomes firmer by theday, and it behooves educators to become familiar with the cell phone tools that arerelevant for teaching in tomorrow‘s--and increasingly ―today‘s‖--classroom.Smartphones have for years offered SMS instant messaging, but the first uses of thattechnology have inevitably been social rather than educational in nature (Reid, 2004.The recent rise in popularity of the iPhone has, however, sparked interest in new usesfor SMS with the advent of new and expanded audiences. One promising online tooloffers instant polling via SMS: polleverywhere.com‘s free account allows up to 30responses per 1-question poll, with unlimited polls per account.This opens up the possibility of classroom response systems that require no studentpurchases of the clicker hardware. While accountability back to the student and gradesare not feasible with polleverywhere.com‘s solution, instructors can harvest quick,anonymous feedback and encourage otherwise reluctant students to engage andparticipate.Apart from texting, modern cell phones come equipped with cameras, which cancombine with email capabilities to offer a potent alternative to writing on whiteboards.Working at their seats, singly or in groups, students can photograph their work andemail it to the instructor, who then can choose from the submissions which to highlighton the lecture hall‘s projection of his computer station, and

  15. Ectopic development of skeletal muscle induced by subcutaneous transplant of rat satellite cells

    Directory of Open Access Journals (Sweden)

    M.G. Fukushima

    2005-03-01

    Full Text Available The present study analyzes the ectopic development of the rat skeletal muscle originated from transplanted satellite cells. Satellite cells (10(6 cells obtained from hindlimb muscles of newborn female 2BAW Wistar rats were injected subcutaneously into the dorsal area of adult male rats. After 3, 7, and 14 days, the transplanted tissues (N = 4-5 were processed for histochemical analysis of peripheral nerves, inactive X-chromosome and acetylcholinesterase. Nicotinic acetylcholine receptors (nAChRs were also labeled with tetramethylrhodamine-labeled alpha-bungarotoxin. The development of ectopic muscles was successful in 86% of the implantation sites. By day 3, the transplanted cells were organized as multinucleated fibers containing multiple clusters of nAChRs (N = 2-4, resembling those from non-innervated cultured skeletal muscle fibers. After 7 days, the transplanted cells appeared as a highly vascularized tissue formed by bundles of fibers containing peripheral nuclei. The presence of X chromatin body indicated that subcutaneously developed fibers originated from female donor satellite cells. Differently from the extensor digitorum longus muscle of adult male rat (87.9 ± 1.0 µm; N = 213, the diameter of ectopic fibers (59.1 µm; N = 213 did not obey a Gaussian distribution and had a higher coefficient of variation. After 7 and 14 days, the organization of the nAChR clusters was similar to that of clusters from adult innervated extensor digitorum longus muscle. These findings indicate the histocompatibility of rats from 2BAW colony and that satellite cells transplanted into the subcutaneous space of adult animals are able to develop and fuse to form differentiated skeletal muscle fibers.

  16. Street navigation using visual information on mobile phones

    DEFF Research Database (Denmark)

    Nguyen, Phuong Giang; Andersen, Hans Jørgen; Høilund, Carsten

    2010-01-01

    Applications with street navigation have been recently introduced on mobile phone devices. A major part of existing systems use integrated GPS as input for indicating the location. However, these systems often fail or make abrupt shifts in urban environment due to occlusion of satellites. Further......Applications with street navigation have been recently introduced on mobile phone devices. A major part of existing systems use integrated GPS as input for indicating the location. However, these systems often fail or make abrupt shifts in urban environment due to occlusion of satellites...

  17. The Westinghouse Series 1000 Mobile Phone: Technology and applications

    Science.gov (United States)

    Connelly, Brian

    1993-01-01

    Mobile satellite communications will be popularized by the North American Mobile Satellite (MSAT) system. The success of the overall system is dependent upon the quality of the mobile units. Westinghouse is designing our unit, the Series 1000 Mobile Phone, with the user in mind. The architecture and technology aim at providing optimum performance at a low per unit cost. The features and functions of the Series 1000 Mobile Phone have been defined by potential MSAT users. The latter portion of this paper deals with who those users may be.

  18. On the phone

    DEFF Research Database (Denmark)

    Paasch, Bettina Sletten

    Background In hospitals clinicians are being equipped with a mobile phone, in order to improve their availability. The phone cannot be silenced, thus it rings when clinicians are performing tasks or are engaged in interaction. Life word led care requires that clinicians use a perceiving eye...... of mobile phones in hospitals, mediate clinicians’ practices. Method Based on an ethnomethodological approach, video recordings of interactions between clinicians and patients at a Danish hospital were conducted. Nexus Analysis (Scollon & Scollon, 2004) was used as a general methodological framework......, complemented with Conversation Analysis (Sacks, 1992) and Goodwin’s (Goodwin, 2000) analytical terminology of contextual configuration. Results The analysis shows how the mobile phone becomes part of the way clinicians arrange their bodies, how they gesture and position themselves in interactions with patients...

  19. Mobile-Phone Microscopes

    Institute of Scientific and Technical Information of China (English)

    程杰

    2008-01-01

    Simple accessories could turn mobile phones into useful medical devices Robi Marrmari stares intently at the screen of his mobile phone.The student is not squinting to tap out yet another daft text message,but looking carefully for the faint blue dots that are the tell-tale diagnostic signature of malaria.Mr.Maamari is a member of a research team led by Dan Fletcher,a professor of bioengineering

  20. Regulation of turkey myogenic satellite cell migration by MicroRNAs miR-128 and miR-24.

    Science.gov (United States)

    Velleman, S G; Harding, R L

    2016-12-05

    Myogenic satellite cells are an adult stem cell responsible for all post-hatch muscle growth in poultry. As a stem cell population, satellite cells are highly heterogeneous, but the origin of this heterogeneity remains unclear. Heterogeneity is, in part, regulated by gene expression. One method of endogenous gene regulation that may contribute to heterogeneity is microRNAs (miRNAs). Two miRNAs previously shown to regulate poultry myogenic satellite cell proliferation and differentiation, miR-128 and miR-24, were studied to determine if they also affected satellite cell migration. Satellite cell migration is an essential step for both proliferation and differentiation. During proliferation, satellite cells will migrate and align to form new myofibers or donate their nuclei to existing myofibers leading to muscle fiber hypertrophy or regeneration. Transient transfection of miRNA specific mimics to each miRNA reduced migration of satellite cells following a cell culture scratch at 72 h of proliferation when the cultures were 90 to 100% confluent. However, only the migration in cells transfected with miR-24 mimics at 24 and 30 h following the scratch was significantly reduced (P ≤ 0.05) to around 70% of the distance migrated by controls. Alternately, transfection with inhibitors specific to miR-128 or miR-24 significantly (P ≤ 0.05) increased migration between 147 and 252% compared to their controls between 24 and 48 h following the scratch. These data demonstrate that miR-128 and miR-24 play a role in myogenic satellite cell migration, which will impact muscle development and growth.

  1. Flow control using audio tones in resonant microfluidic networks: towards cell-phone controlled lab-on-a-chip devices.

    Science.gov (United States)

    Phillips, Reid H; Jain, Rahil; Browning, Yoni; Shah, Rachana; Kauffman, Peter; Dinh, Doan; Lutz, Barry R

    2016-08-16

    Fluid control remains a challenge in development of portable lab-on-a-chip devices. Here, we show that microfluidic networks driven by single-frequency audio tones create resonant oscillating flow that is predicted by equivalent electrical circuit models. We fabricated microfluidic devices with fluidic resistors (R), inductors (L), and capacitors (C) to create RLC networks with band-pass resonance in the audible frequency range available on portable audio devices. Microfluidic devices were fabricated from laser-cut adhesive plastic, and a "buzzer" was glued to a diaphragm (capacitor) to integrate the actuator on the device. The AC flowrate magnitude was measured by imaging oscillation of bead tracers to allow direct comparison to the RLC circuit model across the frequency range. We present a systematic build-up from single-channel systems to multi-channel (3-channel) networks, and show that RLC circuit models predict complex frequency-dependent interactions within multi-channel networks. Finally, we show that adding flow rectifying valves to the network creates pumps that can be driven by amplified and non-amplified audio tones from common audio devices (iPod and iPhone). This work shows that RLC circuit models predict resonant flow responses in multi-channel fluidic networks as a step towards microfluidic devices controlled by audio tones.

  2. Critical amino acids in syndecan-4 cytoplasmic domain modulation of turkey satellite cell growth and development.

    Science.gov (United States)

    Song, Yan; McFarland, Douglas C; Velleman, Sandra G

    2012-02-01

    Syndecan-4 is composed of a core protein and covalently attached glycosaminoglycan (GAG) and N-linked glycosylated (N-glycosylated) chains. The core protein is divided into extracellular, transmembrane, and cytoplasmic domains. The cytoplasmic domain has two conserved regions and a variable region in the middle. The Ser residue in the conserved region 1 and the Tyr residue in the variable region are important in regulating protein kinase C alpha (PKCα) membrane localization and focal adhesion formation. The objective of the current study was to investigate the role of syndecan-4 Ser and Tyr residues in combination with the GAG and N-glycosylated chains in turkey satellite cell proliferation, differentiation, fibroblast growth factor 2 (FGF2) responsiveness, and PKCα membrane localization. Site-directed mutagenesis was used to generate Ser and Tyr mutants with or without GAG and N-glycosylated chains. The wild type and mutant syndecan-4 constructs were transfected into turkey satellite cells. The over-expression of Ser and Tyr mutants increased cell proliferation and differentiation and decreased membrane localization of PKCα. Furthermore, Ser mutants enhanced cellular responsiveness to FGF2. The results from this study are the first demonstration of a role of syndecan-4 cytoplasmic domain Ser and Tyr residues in regulating satellite cell proliferation, differentiation, and the modulation of cellular responsiveness to FGF2.

  3. Plasticity and recovery of skeletal muscle satellite cells during limb regeneration.

    Science.gov (United States)

    Morrison, Jamie I; Borg, Paula; Simon, András

    2010-03-01

    Salamander limb regeneration depends on local progenitors whose progeny are recruited to the new limb. We previously identified a Pax7(+) cell population in skeletal muscle whose progeny have the potential to contribute to the regenerating limb. However, the plasticity of individual Pax7(+) cells, as well as their recovery within the new limb, was unclear. Here, we show that Pax7(+) cells remain present after multiple rounds of limb amputation/regeneration. Pax7(+) cells are found exclusively within skeletal muscle in the regenerating limb and proliferate where the myofibers are growing. Pax7 is rapidly down-regulated in the blastema, and analyses of clonal derivatives show that Pax7(+) cell progeny are not restricted to skeletal muscle during limb regeneration. Our data suggest that the newt regeneration blastema is not entirely a composite of lineage-restricted progenitors. The results demonstrate that except for a transient and subsequently blunted increase, skeletal muscle satellite cells constitute a stable pool of reserve cells for multiple limb regeneration events.-Morrison, J. I., Borg, P., Simon, A. Plasticity and recovery of skeletal muscle satellite cells during limb regeneration.

  4. Effect of Mobile Phone-Induced Electromagnetic Field on Brain Hemodynamics and Human Stem Cell Functioning: Possible Mechanistic Link to Cancer Risk and Early Diagnostic Value of Electronphotonic Imaging.

    Science.gov (United States)

    Bhargav, Hemant; Srinivasan, T M; Varambally, S; Gangadhar, B N; Koka, Prasad

    2015-01-01

    The mobile phones (MP) are low power radio devices which work on electromagnetic fields (EMFs), in the frequency range of 900-1800 MHz. Exposure to MPEMFs may affect brain physiology and lead to various health hazards including brain tumors. Earlier studies with positron emission tomography (PET) have found alterations in cerebral blood flow (CBF) after acute exposure to MPEMFs. It is widely accepted that DNA double-strand breaks (DSBs) and their misrepair in stem cells are critical events in the multistage origination of various leukemia and tumors, including brain tumors such as gliomas. Both significant misbalance in DSB repair and severe stress response have been triggered by MPEMFs and EMFs from cell towers. It has been shown that stem cells are most sensitive to microwave exposure and react to more frequencies than do differentiated cells. This may be important for cancer risk assessment and indicates that stem cells are the most relevant cellular model for validating safe mobile communication signals. Recently developed technology for recording the human bio-electromagnetic (BEM) field using Electron photonic Imaging (EPI) or Gas Discharge Visualisation (GDV) technique provides useful information about the human BEM. Studies have recorded acute effects of Mobile Phone Electromagnetic Fields (MPEMFs) using EPI and found quantifiable effects on human BEM field. Present manuscript reviews evidences of altered brain physiology and stem cell functioning due to mobile phone/cell tower radiations, its association with increased cancer risk and explores early diagnostic value of EPI imaging in detecting EMF induced changes on human BEM.

  5. Satellite cell response to erythropoietin treatment and endurance training in healthy young men

    DEFF Research Database (Denmark)

    Hoedt, Andrea; Christensen, Britt; Nellemann, Birgitte

    2016-01-01

    KEY POINT: Erythropoietin (Epo) treatment may induce myogenic differentiation factor (MyoD) expression and prevent apoptosis in satellite cells (SCs) in murine and in vitro models. Endurance training stimulates SC proliferation in vivo in murine and human skeletal muscle. In the present study, we...... show, in human skeletal muscle, that treatment with an Epo-stimulating agent (darbepoetin-α) in vivo increases the content of MyoD(+) SCs in healthy young men. Moreover, we report that Epo receptor mRNA is expressed in adult human SCs, suggesting that Epo may directly target SCs through ligand......-term Epo treatment during disease conditions involving anaemia may impact SCs and warrants further investigation. Satellite cell (SC) proliferation is observed following erythropoitin treatment in vitro in murine myoblasts and endurance training in vivo in human skeletal muscle. The present study aimed...

  6. Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes.

    Science.gov (United States)

    Morena, Deborah; Maestro, Nicola; Bersani, Francesca; Forni, Paolo Emanuele; Lingua, Marcello Francesco; Foglizzo, Valentina; Šćepanović, Petar; Miretti, Silvia; Morotti, Alessandro; Shern, Jack F; Khan, Javed; Ala, Ugo; Provero, Paolo; Sala, Valentina; Crepaldi, Tiziana; Gasparini, Patrizia; Casanova, Michela; Ferrari, Andrea; Sozzi, Gabriella; Chiarle, Roberto; Ponzetto, Carola; Taulli, Riccardo

    2016-03-17

    Embryonal Rhabdomyosarcoma (ERMS) and Undifferentiated Pleomorphic Sarcoma (UPS) are distinct sarcoma subtypes. Here we investigate the relevance of the satellite cell (SC) niche in sarcoma development by using Hepatocyte Growth Factor (HGF) to perturb the niche microenvironment. In a Pax7 wild type background, HGF stimulation mainly causes ERMS that originate from satellite cells following a process of multistep progression. Conversely, in a Pax7 null genotype ERMS incidence drops, while UPS becomes the most frequent subtype. Murine EfRMS display genetic heterogeneity similar to their human counterpart. Altogether, our data demonstrate that selective perturbation of the SC niche results in distinct sarcoma subtypes in a Pax7 lineage-dependent manner, and define a critical role for the Met axis in sarcoma initiation. Finally, our results provide a rationale for the use of combination therapy, tailored on specific amplifications and activated signaling pathways, to minimize resistance emerging from sarcomas heterogeneity.

  7. Muscle Atrophy Reversed by Growth Factor Activation of Satellite Cells in a Mouse Muscle Atrophy Model

    DEFF Research Database (Denmark)

    Hauerslev, Simon; Vissing, John; Krag, Thomas O

    2014-01-01

    Muscular dystrophies comprise a large group of inherited disorders that lead to progressive muscle wasting. We wanted to investigate if targeting satellite cells can enhance muscle regeneration and thus increase muscle mass. We treated mice with hepatocyte growth factor and leukemia inhibitory...... factor under three conditions: normoxia, hypoxia and during myostatin deficiency. We found that hepatocyte growth factor treatment led to activation of the Akt/mTOR/p70S6K protein synthesis pathway, up-regulation of the myognic transcription factors MyoD and myogenin, and subsequently the negative growth...... control factor, myostatin and atrophy markers MAFbx and MuRF1. Hypoxia-induced atrophy was partially restored by hepatocyte growth factor combined with leukemia inhibitory factor treatment. Dividing satellite cells were three-fold increased in the treatment group compared to control. Finally, we...

  8. The effect of nutritional status and myogenic satellite cell age on turkey satellite cell proliferation, differentiation, and expression of myogenic transcriptional regulatory factors and heparan sulfate proteoglycans syndecan-4 and glypican-1.

    Science.gov (United States)

    Harthan, Laura B; McFarland, Douglas C; Velleman, Sandra G

    2014-01-01

    Posthatch satellite cell mitotic activity is a critical component of muscle development and growth. Satellite cells are myogenic stem cells that can be induced by nutrition to follow other cellular developmental pathways, and whose mitotic activity declines with age. The objective of the current study was to determine the effect of restricting protein synthesis on the proliferation and differentiation, expression of myogenic transcriptional regulatory factors myogenic determination factor 1, myogenin, and myogenic regulatory factor 4, and expression of the heparan sulfate proteoglycans syndecan-4 and glypican-1 in satellite cells isolated from 1-d-, 7-wk-, and 16-wk-old turkey pectoralis major muscle (1 d, 7 wk, and 16 wk cells, respectively) by using variable concentrations of Met and Cys. Four Met concentrations-30 (control), 7.5, 3, or 0 mg/L with 3.2 mg/L of Cys per 1 mg/L of Met-were used for culture of satellite cells to determine the effect of nutrition and age on satellite cell behavior during proliferation and differentiation. Proliferation was reduced by lower Met and Cys concentrations in all ages at 96 h of proliferation. Differentiation was increased in the 1 d Met-restricted cells, whereas the 7 wk cells treated with 3 mg/L of Met had decreased differentiation. Reduced Met and Cys levels from the control did not significantly affect the 16 wk cells at 72 h of differentiation. However, medium with no Met or Cys suppressed differentiation at all ages. The expression of myogenic determination factor 1, myogenin, myogenic regulatory factor 4, syndecan-4, and glypican-1 was differentially affected by age and Met or Cys treatment. These data demonstrate the age-specific manner in which turkey pectoralis major muscle satellite cells respond to nutritional availability and the importance of defining optimal nutrition to maximize satellite cell proliferation and differentiation for subsequent muscle mass accretion.

  9. Effects of Massage on Satellite Cells of Acute Contusive Skeletal Muscles

    Institute of Scientific and Technical Information of China (English)

    胡军; 张喜林; 严隽陶

    2007-01-01

    Objective: To study the mechanism of Tuina in the treatment of skeletal muscle injury. Methods: Rabbits were heavily beaten at gastrocnemius muscle to make acute contusion model and then treated respectively by early Tuina and routine Tuina. The number of satellite cells of skeletal muscles was observed. Results: The number of the satellite cells continued to grow in both groups, and it began to increase significantly 3-5 days after Tuina treatment. Early Tuina treatment produces larger number of satellite cells than routine Tuina treatment.Conclusion: Early Tuina treatment is helpful to the marked recovery of skeletal muscles by increasing the number of satellite cell.%目的:探讨推拿治疗骨骼肌损伤的机理.方法:以重物打击方式造成腓肠肌急性挫伤模型,施以早期推拿治疗和常规推拿治疗,观察骨骼肌卫星细胞数量变化.结果:各组卫星细胞数量均呈持续上升趋势,常规治疗组和早期手法组的卫星细胞数量在3~5 d时就开始有大幅度上升.早期手法组卫星细胞数量多于常规治疗组.结论:早期手法对卫星细胞数增加作用明显有助于骨骼肌功能恢复.

  10. Molecular basis of the myogenic profile of aged human skeletal muscle satellite cells during differentiation

    OpenAIRE

    Pietrangelo, Tiziana; Puglielli, Cristina; Mancinelli, Rosa; Beccafico, Sara; Fanò, Giorgio; Fulle, Stefania

    2009-01-01

    Abstract Sarcopenia is the age-related loss of muscle mass, strength and function. Human muscle proteins are synthesized at a slower rate in the elderly than in young adults, leading to atrophy and muscle mass loss with a decline in the functional capability. Additionally, aging is accompanied by a decrease in the ability of muscle tissue to regenerate following injury or overuse due to the impairment of intervening satellite cells, in which we previously reported oxidative damage ...

  11. Effects of voluntary wheel running on satellite cells in the rat plantaris muscle

    OpenAIRE

    Atsushi Kojima; Mitsutoshi Kurosaka; Yuji Ogura; Hisashi Naito; Shizuo Katamoto; Katsumasa Goto

    2009-01-01

    This study investigated the effects of voluntary wheel running on satellite cells in the rat plantaris muscle. Seventeen 5-week-old male Wistar rats were assigned to a control (n = 5) or training (n = 12) group. Each rat in the training group ran voluntarily in a running-wheel cage for 8 weeks. After the training period, the animals were anesthetized, and the plantaris muscles were removed, weighed, and analyzed immunohistochemically and biochemically. Although there were no significant diffe...

  12. 手机辐射与人体头颅相互作用的仿真分析%The Simulation Analysis of the Interaction between Human Head and Radiation of Cell Phone

    Institute of Scientific and Technical Information of China (English)

    侯建强; 牛中奇; 陈建华; 白冰; 黄华

    2009-01-01

    手机与人体相互作用中涉及两方面问题,一是人体吸收的电磁剂量是否超过限值标准从而对人体造成伤害;二是人体对手机的辐射特性会产生什么影响.采用时域有限差分(FDTD)法经数值仿真进行探讨.结果表明,当手机内置PIFA天线、辐射频率为1 800 MHz、辐射功率为1 W时,人体头颅的总体平均比吸收率未超过ICNIRP颁布的公众基本限值标准,但头颅内任意10 g组织中平均比吸收率的最大值却超过了公众基本限值标准.同时,头颅的影响使手机的辐射特性发生变化,当手机贴于左耳时,手机天线的方向图较之于处在自由空间时的方向图而言发生了向上、向左的偏斜,并且辐射到空间的功率约为辐射总功率的60%,被头颅吸收的功率约为辐射总功率的40%.%The interaction between human and radiation of cell phone involves two problems. One is whether the bioelectromagnetic dose absorbed by human body is beyond the standard limit, the other is what effects the body will have on the radiation of cell phone. Simulation analysis were conducted based on finite difference time domain(FDTD). Because the distance between the head and cell phone is much smaller than the wavelength of electromagnetic waves radiated by cell phone, the interaction could be regarded as a near-field problem in which the head and cell phone were considered as an inseparable whole. At the condition of in-phone PIFA antennas, 1 800 MHz radiation frequency and 1 W radiation power, simulation analysis showed that the average specific absorption rate overall head did not exceed the ICNIRP public promulgation of the basic limit, but the maximum of average specific absorption rate in arbitrary 10 g tissue in the head was more than the basic limit. At the same time, the radiation characteristics of the phone was changed by the influence from the head. When the phone affixed to the left ear, the pattern of the phone antenna was

  13. The Role of Cell-Phones over Use in Anticipation of Sleep Quality, Anxiety and Depression among University Students

    Directory of Open Access Journals (Sweden)

    Morteza Majidaei

    2015-09-01

    Full Text Available Background and Objectives: Due to the quick development and widespread use of mobile phones and its various effects on the interaction and communication, it is important to study its negative effects on the health of cellphone users. The overall aim of the present study was to investigate cellphone overuse as a predictor of sleep quality as well as anxiety and depression among college students. Materials and Methods: This descriptive–correlation study was carried out on all the students of Kharazmi and Payam-e-Noor universities of Karaj during 2014-2015 school years and the sample consisted of 240 persons who were selected by multistage cluster sampling. For data gathering, questionnaires such as cellphone over use scale (COS, Pittsburgh sleep quality index (PSQI and hospital anxiety and depression scale (HADS were used. Data analysis was performed using Pearson’s correlation and multiple regressions (stepwise methods with SPSS 21 software and 0.01 P value. Results: The results of regression showed that the variable of cellphone over use and the variance of sleep quality, anxiety and depression were respectively 0.31% and 0.14%, which predicted and were positively and significantly (r = 0.56, P< 0.01; r= 0.38, P < 0.01 correlated with sleep quality, anxiety and depression. Conclusions: The variable of cellphone overuse can predict and cause changes in sleep quality, anxiety and depression among students and psychotherapists can control these factors to enhance the quality of life and mental health of them.

  14. Fibromodulin: a master regulator of myostatin controlling progression of satellite cells through a myogenic program.

    Science.gov (United States)

    Lee, Eun Ju; Jan, Arif Tasleem; Baig, Mohammad Hassan; Ashraf, Jalaluddin Mohammad; Nahm, Sang-Soep; Kim, Yong-Woon; Park, So-Young; Choi, Inho

    2016-08-01

    Differentiation of muscle satellite cells (MSCs) involves interaction of the proteins present in the extracellular matrix (ECM) with MSCs to regulate their activity, and therefore phenotype. Herein, we report fibromodulin (FMOD), a member of the proteoglycan family participating in the assembly of ECM, as a novel regulator of myostatin (MSTN) during myoblast differentiation. In addition to having a pronounced effect on the expression of myogenic marker genes [myogenin (MYOG) and myosin light chain 2 (MYL2)], FMOD was found to maintain the transcriptional activity of MSTN Moreover, coimmunoprecipitation and in silico studies performed to investigate the interaction of FMOD helped confirm that it antagonizes MSTN function by distorting its folding and preventing its binding to activin receptor type IIB. Furthermore, in vivo studies revealed that FMOD plays an active role in healing by increasing satellite cell recruitment to sites of injury. Together, these findings disclose a hitherto unrecognized regulatory role for FMOD in MSCs and highlight new mechanisms whereby FMOD circumvents the inhibitory effects of MSTN and triggers myoblast differentiation. These findings offer a basis for the design of novel MSTN inhibitors that promote muscle regeneration after injury or for the development of pharmaceutical agents for the treatment of different muscle atrophies.-Lee, E. J., Jan, A. T., Baig, M. H., Ashraf, J. M., Nahm, S.-S., Kim, Y.-W., Park, S.-Y., Choi, I. Fibromodulin: a master regulator of myostatin controlling progression of satellite cells through a myogenic program.

  15. Satellite SAR observation of the sea surface wind field caused by rain cells

    Institute of Scientific and Technical Information of China (English)

    YE Xiaomin; LIN Mingsen; YUAN Xinzhe; DING Jing; XIE Xuetong; ZHANG Yi; XU Ying

    2016-01-01

    Rain cells or convective rain, the dominant form of rain in the tropics and subtropics, can be easy detected by satellite Synthetic Aperture Radar (SAR) images with high horizontal resolution. The footprints of rain cells on SAR images are caused by the scattering and attenuation of the rain drops, as well as the downward airflow. In this study, we extract sea surface wind field and its structure caused by rain cells by using a RADARSAT-2 SAR image with a spatial resolution of 100 m for case study. We extract the sea surface wind speeds from SAR image by using CMOD4 geophysical model function with outside wind directions of NCEP final operational global analysis data, Advance Scatterometer (ASCAT) onboard European MetOp-A satellite and microwave scatterometer onboard Chinese HY-2 satellite, respectively. The root-mean-square errors (RMSE) of these SAR wind speeds, validated against NCEP, ASCAT and HY-2, are 1.48 m/s, 1.64 m/s and 2.14 m/s, respectively. Circular signature patterns with brighter on one side and darker on the opposite side on SAR image are interpreted as the sea surface wind speed (or sea surface roughness) variety caused by downdraft associated with rain cells. The wind speeds taken from the transect profile which superposes to the wind ambient vectors and goes through the center of the circular footprint of rain cell can be fitted as a cosine or sine curve in high linear correlation with the values of no less than 0.80. The background wind speed, the wind speed caused by rain cell and the diameter of footprint of the rain cell with kilometers or tens of kilometers can be acquired by fitting curve. Eight cases interpreted and analyzed in this study all show the same conclusion.

  16. Rainbow trout (Oncorhynchus mykiss) muscle satellite cells are targets of salmonid alphavirus infection.

    Science.gov (United States)

    Biacchesi, Stéphane; Jouvion, Grégory; Mérour, Emilie; Boukadiri, Abdelhak; Desdouits, Marion; Ozden, Simona; Huerre, Michel; Ceccaldi, Pierre-Emmanuel; Brémont, Michel

    2016-01-08

    Sleeping disease in rainbow trout is characterized by an abnormal swimming behaviour of the fish which stay on their side at the bottom of the tanks. This sign is due to extensive necrosis and atrophy of red skeletal muscle induced by the sleeping disease virus (SDV), also called salmonid alphavirus 2. Infections of humans with arthritogenic alphaviruses, such as Chikungunya virus (CHIKV), are global causes of debilitating musculoskeletal diseases. The mechanisms by which the virus causes these pathologies are poorly understood due to the restrictive availability of animal models capable of reproducing the full spectrum of the disease. Nevertheless, it has been shown that CHIKV exhibits a particular tropism for muscle stem cells also known as satellite cells. Thus, SDV and its host constitute a relevant model to study in details the virus-induced muscle atrophy, the pathophysiological consequences of the infection of a particular cell-type in the skeletal muscle, and the regeneration of the muscle tissue in survivors together with the possible virus persistence. To study a putative SDV tropism for that particular cell type, we established an in vivo and ex vivo rainbow trout model of SDV-induced atrophy of the skeletal muscle. This experimental model allows reproducing the full panel of clinical signs observed during a natural infection since the transmission of the virus is arthropod-borne independent. The virus tropism in the muscle tissue was studied by immunohistochemistry together with the kinetics of the muscle atrophy, and the muscle regeneration post-infection was observed. In parallel, an ex vivo model of SDV infection of rainbow trout satellite cells was developed and virus replication and persistence in that particular cell type was followed up to 73 days post-infection. These results constitute the first observation of a specific SDV tropism for the muscle satellite cells.

  17. On spatial distribution of proton radiation belt from solar cell degradation of Akebono satellite

    Science.gov (United States)

    Miyake, W.; Miyoshi, Y.; Matsuoka, A.

    2013-12-01

    Solar cells on any satellite degrade gradually due to severe space radiation environment. We found a fair correlation between the decrease rate of solar cell output current of Akebono satellite orbiting in the inner magnetosphere and trapped proton flux from AP8 model between 1989 and 1992. After 1993, presumably as a result of long-term degradation, variation of solar cell output seems more susceptible to other causes such as high temperature effect, and simple monthly averaged data show no significant relation between them. One of possible causes for the temperature variation of the solar cells is terrestrial heat radiation with changing orientation of solar cell panels towards the earth and another is solar radiation varied with eccentric earth's orbit around the sun. In order to remove the possible temperature effect, we sort the data expected to be least affected by the terrestrial heat radiation from the orbit conditions, and also analyze difference of the output current for a month from that for the same month in the previous year. The analysis method leads us to successfully track a continuous correlation between the decease rate of solar cell output and energetic trapped proton flux up to 1996. We also discuss the best-fitted spatial distribution of energetic protons from comparison with model calculations.

  18. Effects of Garlic (Allium sativum L. Hydroalcoholic Extract on Estrogen, Progesterone and Testosterone Levels in Rats Exposed to Cell Phone Radiation

    Directory of Open Access Journals (Sweden)

    Behnaz Hajiuon

    2014-12-01

    Full Text Available Background: The aim of this study was to investigate the probable effects of radiation and consumption of garlic on estrogen, progesterone and testosterone levels. Materials and Methods: In this experimental study, 5 male and 5 female groups of rat were used: control, sham (under exposed, experimental 1 (receiving garlic extract, and experimental 2 and 3 (receiving both extract and microwaves. After a one month, rats were weighed and serum levels of hormones were measured. Results: In male the mean body weight in the sham showed a significant decrease, whereas, an increase was seen in the experimental 3 compared with sham. Also, mean plasma testosterone levels in experimental 2 and 3 were reduced. Estrogen showed this decrease in all groups. Also in all groups progesterone showed increase. In female the mean body weights in different groups showed no significant changes, whereas a significant increase was seen in serum level of progesterone in experimental 2 and 3. Conclusion: Although, microwaves can cause weight lost, presence of allicin and vitamins A and B in garlic can compensate some of this weight lost. Microwaves and garlic extract have fewer effects on female reproductive system, reflected only in the serum progesterone concentration. Also they reflected in the number of Leydig cells and serum testosterone and estrogen concentration. The differences observed in the responses of male and female to cell phone radiation might be attributed to the position of gonads in the body and sensitivity of testis to heat.

  19. DNA Damage of Lymphocytes in Volunteers after 4 hours Use of Mobile Phone.

    Science.gov (United States)

    Ji, Seonmi; Oh, Eunha; Sul, Donggeun; Choi, Jae Wook; Park, Heechan; Lee, Eunil

    2004-11-01

    There has been gradually increasing concern about the adverse health effects of electromagnetic radiation originating from cell phones which are widely used in modern life. Cell phone radiation may affect human health by increasing free radicals of human blood cells. This study has been designed to identify DNA damage of blood cells by electromagnetic radiation caused by cell phone use. This study investigated the health effect of acute exposure to commercially available cell phones on certain parameters such as an indicator of DNA damage for 14 healthy adult volunteers. Each volunteer during the experiment talked over the cell phone with the keypad facing the right side of the face for 4 hours. The single cell gel electrophoresis assay (Comet assay), which is very sensitive in detecting the presence of DNA strand-breaks and alkali-labile damage in individual cells, was used to assess peripheral blood cells (T-cells, B-cells, granulocytes) from volunteers before and after exposure to cell phone radiation. The parameters of Comet assay measured were Olive Tail Moment and Tail DNA %. The Olive Tail Moment of B-cells and granulocytes and Tail DNA % of B-cells and granulocytes were increased by a statistically significant extent after 4- hour use of a cell phone compared with controls. It is concluded that cell phone radiation caused the DNA damage during the 4 hours of experimental condition. Nonetheless, this study suggested that cell phone use may increase DNA damage by electromagnetic radiation and other contributing factors.

  20. A Fashion for Phones

    Institute of Scientific and Technical Information of China (English)

    MINHHOANG

    2004-01-01

    In a bold move intended to reinvigorate growth in the global mobile phone market, Siemens Mobile last year created Xelibri. This new handset range of radically different shapes and wearable designs has been positioned in the market as a fashion accessory rather than as a communications tool. Both the phones and the accompanying advertising campaign are treating Xelibri as a fashion brand, with handsets being sold in department stores and fashion outlets as well as specialist handset retailers. Two months after the launch in Europe, Xelibri made their Asian debut in Hong Kong,Singapore and China in June 2003.

  1. Commitment of Satellite Cells Expressing the Calcium Channel α2δ1 Subunit to the Muscle Lineage

    Directory of Open Access Journals (Sweden)

    Tammy Tamayo

    2012-01-01

    Full Text Available Satellite cells can maintain or repair muscle because they possess stem cell properties, making them a valuable option for cell therapy. However, cell transplants into skeletal muscle of patients with muscular dystrophy are limited by donor cell attachment, migration, and survival in the host tissue. Cells used for therapy are selected based on specific markers present in the plasma membrane. Although many markers have been identified, there is a need to find a marker that is expressed at different states in satellite cells, activated, quiescent, or differentiated cell. Furthermore, the marker has to be present in human tissue. Recently we reported that the plasma membrane α2δ1 protein is involved in cell attachment and migration in myoblasts. The α2δ1 subunit forms a part of the L-type voltage-dependent calcium channel in adult skeletal muscle. We found that the α2δ1 subunit is expressed in the majority of newly isolated satellite cells and that it appears earlier than the α1 subunits and at higher levels than the β or γ subunits. We also found that those cells that expressed α2δ1 would differentiate into muscle cells. This evidence indicates that the α2δ1 may be used as a marker of satellite cells that will differentiate into muscle.

  2. China's Burgeoning Mobile Phone Industry

    Institute of Scientific and Technical Information of China (English)

    LIWUZHOU

    2003-01-01

    WHEN the cell phone first appeared on the Chinese market in the late 1980s it cost 10,000-20,000 yuan,and was the size of a brick.Regarded as the ultimate status symbol,it was called the da ge da,meaning very influential person.At that time,sales of mobile phones were under state control,and stocks were limited.Purchasers were required to place an order and make an 80 percent down payment.How things have changed!Mobiles are now available in multiple choices of size,color and function,on request.

  3. [Mobile phone based wireless microscopy imaging technology].

    Science.gov (United States)

    Yuan, Yucheng; Liu, Jing

    2011-03-01

    This article proposes a new device named "Wireless Cellscope" that combining mobile phone and optical microscope together. The established wireless microscope platform consists of mobile phone, network monitor, miniaturized microscope or high resolution microscope etc. A series of conceptual experiments were performed on microscopic observation of ordinary objects and mice tumor tissue slices. It was demonstrated that, the new method could acquire microscopy images via a wireless way, which is spatially independent. With small size and low cost, the device thus developed has rather wide applicability in non-disturbing investigation of cell/tissue culture and long distance observation of dangerous biological sample etc.

  4. Cellular Phone Towers, Dorchester County Cell Towers, Published in 2010, 1:1200 (1in=100ft) scale, Dorchester County Government.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:1200 (1in=100ft) scale, was produced all or in part from Orthoimagery information as of 2010. It is described as...

  5. Cellular Phone Towers, Cell Tower buffer sectors divided into N, S, E and W, Published in 2008, 1:63360 (1in=1mile) scale, Graham County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:63360 (1in=1mile) scale, was produced all or in part from Not Provided information as of 2008. It is described as...

  6. Cellular Phone Towers, Cell tower location and elevation, Published in 2008, 1:2400 (1in=200ft) scale, Portage County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Published Reports/Deeds information as of 2008. It is...

  7. Cellular Phone Towers, Green Co Cell Towers, Published in 2007, 1:4800 (1in=400ft) scale, MSA Professional Services.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:4800 (1in=400ft) scale, was produced all or in part from Hardcopy Maps information as of 2007. It is described as...

  8. Mobile Phone Radiation and Cancer

    Science.gov (United States)

    Plotz, Thomas

    2017-01-01

    A possible link between cancer and the usage of mobile phones has been widely discussed in the media in the last 10 years. It is no surprise that students keep asking their physics teacher for advice regarding the handling of mobile phones and mobile phone radiation. This article aims to help teachers include this interesting topic in the…

  9. Mobile Phone Antenna Performance 2016

    DEFF Research Database (Denmark)

    Pedersen, Gert F.

    2016-01-01

    This study investigates the antenna performance of a number of mobile phones widely used in the Nordic Countries. The study is supported by the Nordic Council of Ministers. The antenna performance of the phones is vital for the phones ability to ensure radio coverage in low signal situations...

  10. 77 FR 2734 - Proposed Collection; Comment Request: Solar Cell: A Mobile UV Manager for Smart Phones (NCI)

    Science.gov (United States)

    2012-01-19

    ... HUMAN SERVICES National Institutes of Health Proposed Collection; Comment Request: Solar Cell: A Mobile... (OMB) for review and approval. Proposed Collection: Title: Solar Cell: A Mobile UV Manager for Smart... technology to aid users in protecting their skin from damaging ultraviolet radiation (UV) in sunlight,...

  11. 77 FR 4334 - Proposed Collection; Comment Request; Solar Cell: A Mobile UV Manager for Smart Phones (NCI)

    Science.gov (United States)

    2012-01-27

    ... HUMAN SERVICES National Institutes of Health Proposed Collection; Comment Request; Solar Cell: A Mobile... (OMB) for review and approval. Proposed Collection: Title: Solar Cell: A Mobile UV Manager for Smart... technology to aid users in protecting their skin from damaging ultraviolet radiation (UV) in sunlight,...

  12. Reduced satellite cell number in situ in muscular contractures from children with cerebral palsy.

    Science.gov (United States)

    Dayanidhi, Sudarshan; Dykstra, Peter B; Lyubasyuk, Vera; McKay, Bryon R; Chambers, Henry G; Lieber, Richard L

    2015-07-01

    Satellite cells (SC) are quiescent adult muscle stem cells critical for postnatal development. Children with cerebral palsy have impaired muscular growth and develop contractures. While flow cytometry previously demonstrated a reduced SC population, extracellular matrix abnormalities may influence the cell isolation methods used, systematically isolating fewer cells from CP muscle and creating a biased result. Consequently, the purpose of this study was to use immunohistochemistry on serial muscle sections to quantify SC in situ. Serial cross-sections from human gracilis muscle biopsies (n = 11) were labeled with fluorescent antibodies for Pax7 (SC transcriptional marker), laminin (basal lamina), and 4',6-diamidino-2-phenylindole (nuclei). Fluorescence microscopy under high magnification was used to identify SC based on labeling and location. Mean SC/100 myofibers was reduced by ∼70% (p muscle growth and apparent decreased responsiveness of CP muscle to exercise. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

  13. Measuring Mobile Phone Use

    DEFF Research Database (Denmark)

    Boase, Jeff; Ling, Richard

    2013-01-01

    In this paper we examine how well two types of self-report measures adequately operationalize frequency of mobile phone use by comparing them to server log data. Our self-report measures of voice and SMS text messaging activity are drawn from a nationally representative survey of adults living in...

  14. iPhone paper

    Science.gov (United States)

    2016-12-01

    Could you write a scientific manuscript using just your iPhone? Well, when Christoph Bartneck at the University of Canterbury in New Zealand was invited to submit a paper to the International Conference on Atomic and Nuclear Physics, in Atlanta, Georgia, in November, he decided to do just that.

  15. On the phone

    DEFF Research Database (Denmark)

    Paasch, Bettina Sletten

    , complemented with Conversation Analysis (Sacks, 1992) and Goodwin’s (Goodwin, 2000) analytical terminology of contextual configuration. Results The analysis shows how the mobile phone becomes part of the way clinicians arrange their bodies, how they gesture and position themselves in interactions with patients...

  16. The vascular endothelial growth factor expression and vascular regeneration in infarcted myocardium by skeletal muscle satellite cells

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Background Myocardial infarction results in tissue necrosis, leading to cell loss and ultimately to cardiac failure. Implantation of skeletal muscle satellite cells into the scar area may compensate for the cell loss and provides a new strategy for infarct therapy. Vascular endothelial growth factor (VEGF) is a promising reagent for inducing myocardial angiogenesis. Skeletal myoblast transplantation has been shown to improve cardiac function in chronic heart failure models by regenerating muscle. We hypothesized that VEGF expression and vascular regeneration increased in infarcted myocardium by skeletal muscle satellite cells, which can promote vascular producing and improve survival environment in infarcted myocardium.Methods The skeletal muscle satellite cells were implanted into the infarcted myocardium in a model through ligated left anterior artery in Louis Inbrad Strain rat. Specimens were got for identifying the expression of VEGF and the density of vascular by immunochemical method at two weeks after implantation. Results The proliferation and differentiation of the skeletal muscle satellite cell was very well. The expression of VEGF was higher in the implanted group (146.83±2.49) than that in the control group (134.26±6.84) (P<0.05). The vascular density in the implanted group (13.00±1.51) was also higher than that in the control (10.68±1.79) (P<0.05). Conclusion The implanted satellite cell could excrete growth factor that would induce angiogenesis and improve cell survival environment in infarcted myocardium.

  17. The long, the short, and the micro: a polyA tale of Pax3 in satellite cells.

    Science.gov (United States)

    Pasut, Alessandra; Rudnicki, Michael A

    2012-03-02

    The use of alternative polyadenylation sites is emerging as an important regulator of gene expression. In this issue of Cell Stem Cell, Boutet et al. (2012) report that alternative 3'UTRs of the Pax3 transcript restrict its expression to axial satellite cells through miR-mediated targeting of one of the isoforms. Copyright © 2012 Elsevier Inc. All rights reserved.

  18. Satellite Cells CD44 Positive Drive Muscle Regeneration in Osteoarthritis Patients

    Directory of Open Access Journals (Sweden)

    Manuel Scimeca

    2015-01-01

    Full Text Available Age-related bone diseases, such as osteoarthritis and osteoporosis, are strongly associated with sarcopenia and muscle fiber atrophy. In this study, we analyzed muscle biopsies in order to demonstrate that, in osteoarthritis patients, both osteophytes formation and regenerative properties of muscle stem cells are related to the same factors. In particular, thanks to immunohistochemistry, transmission electron microscopy, and immunogold labeling we investigated the role of BMP-2 in muscle stem cells activity. In patients with osteoarthritis both immunohistochemistry and transmission electron microscopy allowed us to note a higher number of CD44 positive satellite muscle cells forming syncytium. Moreover, the perinuclear and cytoplasmic expression of BMP-2 assessed by in situ molecular characterization of satellite cells syncytia suggest a very strict correlation between BMP-2 expression and muscle regeneration capability. Summing up, the higher BMP-2 expression in osteoarthritic patients could explain the increased bone mineral density as well as decreased muscle atrophy in osteoarthrosic patients. In conclusion, our results suggest that the control of physiological BMP-2 balance between bone and muscle tissues may be considered as a potential pharmacological target in bone-muscle related pathology.

  19. Knowledge, attitudes and practice on cell phone radiation among college freshmen and sophomores%某高校低年级大学生手机辐射危害知识态度行为分析

    Institute of Scientific and Technical Information of China (English)

    阎艺然; 曾洁; 石璐; 代子豪; 俞天杰; 卢晓翠

    2013-01-01

    Objective To understand the knowledge-attitude-practice on cell phone radiation among college freshmen and sophomores,and to provide useful information for the development of the college students' health education.Methods By using cluster random sampling method,one class of freshmen and one class of sophomores were selected in one medical university and one non-medical university.A total of 345 participants filled in the self-designed questionnaire.Results About 98.84% of the students were aware of cell phone radiation.More than 70% of them knew that cell phone radiation was strongest when the signal was very weak,the moment connected and calling.The awareness rate among medical students and sophomores was higher than freshmen from non medical students (P<0.01).More than 80% of students cared about cell phone radiation and paid attention to protection information.Female (73.53%) were more likely to make a phone call when walking than male (62.62%).About 60% of students slept with cell phones under their pillows,with students from non-medical university being higher than that from medical university (P<0.01).Conclusion Education should be strengthened to promote awareness of cell phone radiation among college students,and protect them through changing incorrect cell phone using behaviors.%目的 了解大学生有关手机辐射的知识、信念、行为现状,为开展大学生健康教育提供依据.方法 整群随机抽取某高校医学专业和非医学专业的大一、大二各1个班学生共345名,现场填写自行设计的调查问卷.结果 98.84%的学生知晓手机可以产生辐射;对于信号弱时、刚接通时以及通话时手机辐射大的知晓率超过70%;多数医学生和大二学生对手机辐射危害知识的知晓率更高(P<0.05或P<0.01);80%以上的学生介意手机辐射危害并关注手机辐射危害防护知识;女生(73.53%)较男生(62.62%)更喜欢打电话时走动(P<0.05);60

  20. Satellite cell activation induced by aerobic muscle adaptation in response to endurance exercise in humans and rodents.

    Science.gov (United States)

    Abreu, Phablo; Mendes, Sávio Victor Diógenes; Ceccatto, Vânia Marilande; Hirabara, Sandro Massao

    2017-02-01

    Although the requirement of satellite cells activation and expansion following injury, mechanical load or growth stimulus provoked by resistance exercise has been well established, their function in response to aerobic exercise adaptation remains unclear. A clear relationship between satellite cell expansion in fiber-type specific myosin heavy chain and aerobic performance has been related, independent of myonuclear accretion or muscle growth. However, the trigger for this activation process is not fully understood yet and it seems to be a multi-faceted and well-orchestrated process. Emerging in vitro studies suggest a role for metabolic pathways and oxygen availability for satellite cell activation, modulating the self-renewal potential and cell fate control. The goal of this review is to describe and discuss the current knowledge about the satellite cell activation and expansion in response to aerobic exercise adaptation in human and rodent models. Additionally, findings about the in vitro metabolic control, which seems be involved in the satellite cell activation and cell fate control, are presented and discussed.

  1. Investigation of the effects of distance from sources on apoptosis, oxidative stress and cytosolic calcium accumulation via TRPV1 channels induced by mobile phones and Wi-Fi in breast cancer cells.

    Science.gov (United States)

    Çiğ, Bilal; Nazıroğlu, Mustafa

    2015-10-01

    TRPV1 is a Ca2+ permeable channel and gated by noxious heat, oxidative stress and capsaicin (CAP). Some reports have indicated that non-ionized electromagnetic radiation (EMR)-induces heat and oxidative stress effects. We aimed to investigate the effects of distance from sources on calcium signaling, cytosolic ROS production, cell viability, apoptosis, plus caspase-3 and -9 values induced by mobile phones and Wi-Fi in breast cancer cells MCF-7 human breast cancer cell lines were divided into A, B, C and D groups as control, 900, 1800 and 2450 MHz groups, respectively. Cells in Group A were used as control and were kept in cell culture conditions without EMR exposure. Groups B, C and D were exposed to the EMR frequencies at different distances (0 cm, 1 cm, 5 cm, 10 cm, 20 cm and 25 cm) for 1h before CAP stimulation. The cytosolic ROS production, Ca2+ concentrations, apoptosis, caspase-3 and caspase-9 values were higher in groups B, C and D than in A group at 0 cm, 1 cm and 5 cm distances although cell viability (MTT) values were increased by the distances. There was no statistically significant difference in the values between control, 20 and 25 cm. Wi-Fi and mobile phone EMR placed within 10 cm of the cells induced excessive oxidative responses and apoptosis via TRPV1-induced cytosolic Ca2+ accumulation in the cancer cells. Using cell phones and Wi-Fi sources which are farther away than 10 cm may provide useful protection against oxidative stress, apoptosis and overload of intracellular Ca2+. This article is part of a Special Issue entitled: Membrane channels and transporters in cancers.

  2. Candidate solar cell materials for photovoltaic conversion in a solar power satellite /SPS/

    Science.gov (United States)

    Glaser, P. E.; Almgren, D. W.

    1978-01-01

    In recognition of the obstacles to solar-generated baseload power on earth, proposals have been made to locate solar power satellites in geosynchronous earth orbit (GEO), where solar energy would be available 24 hours a day during most of the time of the year. In an SPS, the electricity produced by solar energy conversion will be fed to microwave generators forming part of a planar phase-array transmitting antenna. The antenna is designed to precisely direct a microwave beam of very low intensity to one or more receiving antennas at desired locations on earth. At the receiving antenna, the microwave energy will be safely and efficiently reconverted to electricity and then be transmitted to consumers. An SPS system will include a number of satellites in GEO. Attention is given to the photovoltaic option for solar energy conversion in GEO, solar cell requirements, the availability of materials, the implication of large production volumes, requirements for high-volume manufacture of solar cell arrays, and the effects of concentration ratio on solar cell array area.

  3. Transcription of Satellite III non-coding RNAs is a general stress response in human cells

    Science.gov (United States)

    Valgardsdottir, Rut; Chiodi, Ilaria; Giordano, Manuela; Rossi, Antonio; Bazzini, Silvia; Ghigna, Claudia; Riva, Silvano; Biamonti, Giuseppe

    2008-01-01

    In heat-shocked human cells, heat shock factor 1 activates transcription of tandem arrays of repetitive Satellite III (SatIII) DNA in pericentromeric heterochromatin. Satellite III RNAs remain associated with sites of transcription in nuclear stress bodies (nSBs). Here we use real-time RT-PCR to study the expression of these genomic regions. Transcription is highly asymmetrical and most of the transcripts contain the G-rich strand of the repeat. A low level of G-rich RNAs is detectable in unstressed cells and a 104-fold induction occurs after heat shock. G-rich RNAs are induced by a wide range of stress treatments including heavy metals, UV-C, oxidative and hyper-osmotic stress. Differences exist among stressing agents both for the kinetics and the extent of induction (>100- to 80.000-fold). In all cases, G-rich transcripts are associated with nSBs. On the contrary, C-rich transcripts are almost undetectable in unstressed cells and modestly increase after stress. Production of SatIII RNAs after hyper-osmotic stress depends on the Tonicity Element Binding Protein indicating that activation of the arrays is triggered by different transcription factors. This is the first example of a non-coding RNA whose transcription is controlled by different transcription factors under different growth conditions. PMID:18039709

  4. Space satellite power system. [conversion of solar energy by photovoltaic solar cell arrays

    Science.gov (United States)

    Glaser, P. E.

    1974-01-01

    The concept of a satellite solar power station was studied. It is shown that it offers the potential to meet a significant portion of future energy needs, is pollution free, and is sparing of irreplaceable earth resources. Solar energy is converted by photovoltaic solar cell arrays to dc energy which in turn is converted into microwave energy in a large active phased array. The microwave energy is beamed to earth with little attenuation and is converted back to dc energy on the earth. Economic factors are considered.

  5. Cellular phones and their hazards: the current evidence.

    Science.gov (United States)

    Munshi, Anusheel; Jalali, Rakesh

    2002-01-01

    The past decade has seen an exponential increase globally in the use of cellular phones (popularly known as mobile or cell phones). These phones are convenient and trendy. Discarding the wire means that the communication is through electromagnetic waves, which could have potential hazards. Alarmist reports in the lay press and high profile lawsuits, particularly in the West, have attracted attention to the possible harmful effects of cellular phones. Adverse effects investigated by various clinical trials include the possible link to increased risk of vehicular accidents, leukaemias, sleep disturbances and the more serious brain tumours. Available level II evidence suggests that the only proven side-effect is an increased risk of vehicular accidents. So far, all studies have consistently negated any association between cellular phones and brain tumours. Yet, the final word remains to be said.

  6. Analyses of the differentiation potential of satellite cells from myoD-/-, mdx, and PMP22 C22 mice

    Directory of Open Access Journals (Sweden)

    Huxley Clare

    2005-03-01

    Full Text Available Abstract Background Sporadic and sometimes contradictory studies have indicated changes in satellite cell behaviour associated with the progressive nature of human Duchenne muscular dystrophy (DMD. Satellite cell proliferation and number are reportedly altered in DMD and the mdx mouse model. We recently found that satellite cells in MSVski transgenic mice, a muscle hypertrophy model showing progressive muscle degeneration, display a severe ageing-related differentiation defect in vitro. We tested the hypothesis that similar changes contribute to the gradual loss of muscle function with age in mdx and PMP22 mice, a model of human motor and sensory neuropathy type 1A (HMSN1A. Methods Single extensor digitorum longus muscle fibres were cultured from mdx and PMP22 mice and age- and genetic background-matched controls. Mice at several ages were compared with regard to the differentiation of satellite cells, assayed as the proportion of desmin-expressing cells that accumulated sarcomeric myosin heavy chain. Results Satellite cells of 2 month, 6 month, and 12 month old mdx mice were capable of differentiating to a similar extent to age-matched wild type control animals in an in vitro proliferation/differentiation model. Strikingly, differentiation efficiency in individual 6 month and 12 month old mdx animals varies to a much higher extent than in age-matched controls, younger mdx animals, or PMP22 mice. In contrast, differentiation of myoblasts from all myoD null mice assayed was severely impaired in this assay system. The defect in satellite cell differentiation that occurs in some mdx animals arises from a delay in differentiation that is not overcome by IGF-1 treatment at any phase of cultivation. Conclusion Overall, a defect in satellite cell differentiation above that arising through normal ageing does not occur in mdx or PMP22 mouse models of human disease. Nonetheless, the impaired differentiation of satellite cells from some mdx animals

  7. Histological and histochemical study of the protective role of rosemary extract against harmful effect of cell phone electromagnetic radiation on the parotid glands.

    Science.gov (United States)

    Ghoneim, Fatma M; Arafat, Eetmad A

    2016-06-01

    Electromagnetic fields (EMFs) are a class of non-ionizing radiation (NIR) that is emitted from mobile phone. It may have hazardous effects on parotid glands. So, we aimed to investigate the histological and histochemical changes of the parotid glands of rats exposed to mobile phone and study the possible protective role of rosemary against its harmful effect. Forty adult male albino rats were used in this study. They were classified into 4 equal groups. Group I (control), group II (control receiving rosemary), group III (mobile phone exposed group) and group IV (mobile exposed, rosemary treated group). Parotid glands were dissected out for histological and histochemical study. Moreover, measurement of oxidative stress markers; malondialdehyde (MDA) and total antioxidant capacity (TAC) was done. The results of this study revealed that rosemary has protective effect through improving the histological and histochemical picture of the parotid gland in addition of its antioxidant effect. It could be concluded from the current study, that exposure of parotid gland of rat models to electromagnetic radiation of mobile phone resulted in structural changes at the level of light and electron microscopic examination which could be explained by oxidative stress effect of mobile phone. Rosemary could play a protective role against this harmful effect through its antioxidant activity.

  8. Mobile Phone Faraday Cage

    CERN Document Server

    French, M M J

    2011-01-01

    A Faraday cage is an interesting physics phenomena where an electromagnetic wave can be excluded from a volume of space by enclosure with an electrically conducting material. The practical application of this in the classroom is to block the signal to a mobile phone by enclosing it in a metal can! The background of the physics behind this is described in some detail followed by a explanation of some demonstrations and experiments which I have used.

  9. Satellite cells senescence in limb muscle of severe patients with COPD.

    Directory of Open Access Journals (Sweden)

    Marie-Eve Thériault

    Full Text Available RATIONALE: The maintenance of peripheral muscle mass may be compromised in chronic obstructive pulmonary disease (COPD due to premature cellular senescence and exhaustion of the regenerative potential of the muscles. METHODS: Vastus lateralis biopsies were obtained from patients with COPD (n = 16 and healthy subjects (n = 7. Satellite cell number and the proportion of central nuclei, as a marker of muscle regenerative events, were assessed on cryosections. Telomere lengths, used as a marker of cellular senescence, were determined using Southern blot analyses. RESULTS: Central nuclei proportion was significantly higher in patients with COPD with a preserved muscle mass compared to controls and patients with COPD with muscle atrophy (p<0.001. In COPD, maximal telomere length was significantly decreased compared to controls (p<0.05. Similarly, minimal telomere length was significantly reduced in GOLD III-IV patients with muscle atrophy compared to controls (p<0.005. Minimal, mean and maximum telomere lengths correlated with mid-thigh muscle cross-sectional area (MTCSA (R = 0.523, p = 0.005; R = 0.435, p = 0.019 and R = 0.491, p = 0.009, respectively. CONCLUSIONS: Evidence of increased regenerative events was seen in GOLD III-IV patients with preserved muscle mass. Shortening of telomeres in GOLD III-IV patients with muscle atrophy is consistent with an increased number of senescent satellite cells and an exhausted muscle regenerative capacity, compromising the maintenance of muscle mass in these individuals.

  10. Label-free screening of niche-to-niche variation in satellite stem cells using functionalized pores

    Science.gov (United States)

    Chapman, Matthew R.; Balakrishnan, Karthik; Conboy, Michael J.; Mohanty, Swomitra; Jabart, Eric; Huang, Haiyan; Hack, James; Conboy, Irina M.; Sohn, Lydia L.

    2012-02-01

    Combinations of surface markers are currently used to identify muscle satellite cells. Using pores functionalized with specific antibodies and measuring the transit time of cells passing through these pores, we discovered remarkable heterogeneity in the expression of these markers in muscle (satellite) stem cells that reside in different single myofibers. Microniche-specific variation in stem cells of the same organ has not been previously described, as bulk analysis does not discriminate between separate myofibers or even separate hind-leg muscle groups. We found a significant population of Sca-1+ satellite cells that form myotubes, thereby demonstrating the myogenic potential of Sca-1+ cells, which are currently excluded in bulk sorting. Finally, using our label-free pore screening technique, we have been able to quantify directly surface expression of Notch1 without activation of the Notch pathway. We show for the first time Notch1-expression heterogeneity in unactivated satellite cells. The discovery of fiber-to-fiber variations prompts new research into the reasons for such diversity in muscle stem cells.

  11. Integrating group counseling, cell phone messaging, and participant-generated songs and dramas into a microcredit program increases Nigerian women's adherence to international breastfeeding recommendations.

    Science.gov (United States)

    Flax, Valerie L; Negerie, Mekebeb; Ibrahim, Alawiyatu Usman; Leatherman, Sheila; Daza, Eric J; Bentley, Margaret E

    2014-07-01

    In northern Nigeria, interventions are urgently needed to narrow the large gap between international breastfeeding recommendations and actual breastfeeding practices. Studies of integrated microcredit and community health interventions documented success in modifying health behaviors but typically had uncontrolled designs. We conducted a cluster-randomized controlled trial in Bauchi State, Nigeria, with the aim of increasing early breastfeeding initiation and exclusive breastfeeding among female microcredit clients. The intervention had 3 components. Trained credit officers led monthly breastfeeding learning sessions during regularly scheduled microcredit meetings for 10 mo. Text and voice messages were sent out weekly to a cell phone provided to small groups of microcredit clients (5-7 women). The small groups prepared songs or dramas about the messages and presented them at the monthly microcredit meetings. The control arm continued with the regular microcredit program. Randomization occurred at the level of the monthly meeting groups. Pregnant clients were recruited at baseline and interviewed again when their infants were aged ≥6 mo. Logistic regression models accounting for clustering were used to estimate the odds of performing recommended behaviors. Among the clients who completed the final survey (n = 390), the odds of exclusive breastfeeding to 6 mo (OR: 2.4; 95% CI: 1.4, 4.0) and timely breastfeeding initiation (OR: 2.6; 95% CI: 1.6, 4.1) were increased in the intervention vs. control arm. Delayed introduction of water explained most of the increase in exclusive breastfeeding among clients receiving the intervention. In conclusion, a breastfeeding promotion intervention integrated into microcredit increased the likelihood that women adopted recommended breastfeeding practices. This intervention could be scaled up in Nigeria, where local organizations provide microcredit to >500,000 clients. Furthermore, the intervention could be adopted more widely

  12. Development of Cell Phone Application for Blood Glucose Self-Monitoring Based on ISO/IEEE 11073 and HL7 CCD

    Science.gov (United States)

    Park, Hyun Sang; Cho, Hune

    2015-01-01

    Objectives The objectives of this research were to develop and evaluate a cell phone application based on the standard protocol for personal health devices and the standard information model for personal health records to support effective blood glucose management and standardized service for patients with diabetes. Methods An application was developed for Android 4.0.3. In addition, an IEEE 11073 Manager, Medical Device Encoding Rule, and Bluetooth Health Device Profile Connector were developed for standardized health communication with a glucometer, and a Continuity of Care Document (CCD) Composer and CCD Parser were developed for CCD document exchange. The developed application was evaluated by five healthcare professionals and 87 users through a questionnaire comprising the following variables: usage intention, effort expectancy, social influence, facilitating condition, perceived risk, and voluntariness. Results As a result of the evaluation of usability, it was confirmed that the developed application is useful for blood glucose self-monitoring by diabetic patients. In particular, the healthcare professionals stated their own views that the application is useful to observe the trends in blood glucose change through the automatic function which records a blood glucose level measured using Bluetooth function, and the function which checks accumulated records of blood glucose levels. Also, a result of the evaluation of usage intention was 3.52 ± 0.42 out of 5 points. Conclusions The application developed by our research team was confirmed by the verification of healthcare professionals that accurate feedback can be provided to healthcare professionals during the management of diabetic patients or education for glucose management. PMID:25995960

  13. Development of Cell Phone Application for Blood Glucose Self-Monitoring Based on ISO/IEEE 11073 and HL7 CCD.

    Science.gov (United States)

    Park, Hyun Sang; Cho, Hune; Kim, Hwa Sun

    2015-04-01

    The objectives of this research were to develop and evaluate a cell phone application based on the standard protocol for personal health devices and the standard information model for personal health records to support effective blood glucose management and standardized service for patients with diabetes. An application was developed for Android 4.0.3. In addition, an IEEE 11073 Manager, Medical Device Encoding Rule, and Bluetooth Health Device Profile Connector were developed for standardized health communication with a glucometer, and a Continuity of Care Document (CCD) Composer and CCD Parser were developed for CCD document exchange. The developed application was evaluated by five healthcare professionals and 87 users through a questionnaire comprising the following variables: usage intention, effort expectancy, social influence, facilitating condition, perceived risk, and voluntariness. As a result of the evaluation of usability, it was confirmed that the developed application is useful for blood glucose self-monitoring by diabetic patients. In particular, the healthcare professionals stated their own views that the application is useful to observe the trends in blood glucose change through the automatic function which records a blood glucose level measured using Bluetooth function, and the function which checks accumulated records of blood glucose levels. Also, a result of the evaluation of usage intention was 3.52 ± 0.42 out of 5 points. The application developed by our research team was confirmed by the verification of healthcare professionals that accurate feedback can be provided to healthcare professionals during the management of diabetic patients or education for glucose management.

  14. Circularly Polarized Transparent Microstrip Patch Reflectarray Integrated with Solar Cell for Satellite Applications

    Directory of Open Access Journals (Sweden)

    S. H. Zainud-Deen

    2016-01-01

    Full Text Available Circularly polarized (CP transparent microstrip reflectarray antenna is integrated with solar cell for small satellite applications at 10 GHz. The reflectarray unit cell consists of a perfect electric conductor (PEC square patch printed on an optically transparent substrate with the PEC ground plane. A comparison between using transparent conducting polymers and using the PEC in unit-cell construction has been introduced. The waveguide simulator is used to calculate the required compensation phase of each unit cell in the reflectarray. The radiation characteristics of 13 × 13 CP transparent reflectarray antenna are investigated. A circularly polarized horn antenna is used to feed the reflectarray. The solar cell is incorporated with the transparent reflectarray on the same area. The solar-cell integration with the reflectarray reduces the maximum gain by about 0.5 dB due to the increase in the magnitude of the reflection coefficient. The results are calculated using the finite integral technique (FIT.

  15. Mobile Phone Radiation: Physiological & Pathophysiologcal Considerations.

    Science.gov (United States)

    K Sri, Nageswari

    2015-01-01

    It is documented that electromagnetic emissions from mobile phones can interfere with brain's signal processing activity due to their oscillatory similitude to the inherent rhythms of the brain, akin to "electromagnetic interference" observed while using mobile phones in aeroplanes. At high power density levels, thermal effects occur, some of which can be attributed to heat induced stress mechanisms. The less understood non-thermal effects occur at low radio frequency/microwave power density levels and are not accompanied by any body temperature rise. The safety standards set by international agencies are based on thermal effects. For the mobile phones, ICNIRP 1998 guidelines restrict spatial peak of microwave exposure to 2 W/Kg SAR values averaged over 10 g of tissue for 6 minutes. Some of the reported electromagnetic radiation (EMR) induced adverse effects are brain tumours, male infertility and immune dysfunction with increased susceptibility to infections. Pathophysiological mechanisms of interaction of EMR at plasma membrane are calcium efflux from cell membranes, increased expression of stress proteins, influence on channels/gap junctions in cell membrane, overproduction of reactive oxygen species, ornithine decarboxylase activation, reduction in melatonin levels, decrease in protein kinase C activity, damage to DNA and change in gene expression in brain cells and altered blood-brain barrier. There are equal number of conflicting reports in literature regarding EMR exposure and brain tumours. A comprehensive review concludes "overall the studies published to date do not demonstrate an increased risk within approximately 10 years of use for any tumour of the brain or any other head tumour." Another review summarises that there is "enough data to convince that long-term exposure to low intensity EMR below the ICNIRP guidelines can promote cancer development". However the time limit for exposure has been suggested as more than 10 years. For conducting

  16. Study on Cell Error Rate of a Satellite ATM System Based on CDMA

    Institute of Scientific and Technical Information of China (English)

    赵彤宇; 张乃通

    2003-01-01

    In this paper, the cell error rate (CER) of a CDMA-based satellite ATM system is analyzed. Two fading models, i.e. the partial fading model and the total fading model are presented according to multi-path propagation fading and shadow effect. Based on the total shadow model, the relation of CER vs. the number of subscribers at various elevations under 2D-RAKE receiving and non-diversity receiving is got. The impact on cell error rate with pseudo noise (PN) code length is also considered. The result that the maximum likelihood combination of multi-path signal would not improve the system performance when multiple access interference (MAI) is small, on the contrary the performance may be even worse is abtained.

  17. Potential Role of Omega-3 Fatty Acids on the Myogenic Program of Satellite Cells.

    Science.gov (United States)

    Bhullar, Amritpal S; Putman, Charles T; Mazurak, Vera C

    2016-01-01

    Skeletal muscle loss is associated with aging as well as pathological conditions. Satellite cells (SCs) play an important role in muscle regeneration. Omega-3 fatty acids are widely studied in a variety of muscle wasting diseases; however, little is known about their impact on skeletal muscle regeneration. The aim of this review is to evaluate studies examining the effect of omega-3 fatty acids, α-linolenic acid, eicosapentaenoic acid, and docosahexaenoic acid on the regulation of SC proliferation and differentiation. This review highlights mechanisms by which omega-3 fatty acids may modulate the myogenic program of the stem cell population within skeletal muscles and identifies considerations for future studies. It is proposed that minimally three myogenic transcriptional regulatory factors, paired box 7 (Pax7), myogenic differentiation 1 protein, and myogenin, should be measured to confirm the stage of SCs within the myogenic program affected by omega-3 fatty acids.

  18. Communication between neuronal somata and satellite glial cells in sensory ganglia.

    Science.gov (United States)

    Huang, Li-Yen M; Gu, Yanping; Chen, Yong

    2013-10-01

    Studies of the structural organization and functions of the cell body of a neuron (soma) and its surrounding satellite glial cells (SGCs) in sensory ganglia have led to the realization that SGCs actively participate in the information processing of sensory signals from afferent terminals to the spinal cord. SGCs use a variety ways to communicate with each other and with their enwrapped soma. Changes in this communication under injurious conditions often lead to abnormal pain conditions. "What are the mechanisms underlying the neuronal soma and SGC communication in sensory ganglia?" and "how do tissue or nerve injuries affect the communication?" are the main questions addressed in this review. Copyright © 2013 Wiley Periodicals, Inc.

  19. Optimized High Temperature PEM Fuel Cell & High Pressure PEM Electrolyser for Regenerative Fuel Cell Systems in GEO Telecommunication Satellites

    Directory of Open Access Journals (Sweden)

    Farnes Jarle

    2017-01-01

    Full Text Available Next generation telecommunication satellites will demand increasingly more power. Power levels up to 50 kW are foreseen for the next decades. Battery technology that can sustain up to 50 kW for eclipse lengths of up to 72 minutes will represent a major impact on the total mass of the satellite, even with new Li-ion battery technologies. Regenerative fuel cell systems (RFCS were identified years ago as a possible alternative to rechargeable batteries. CMR Prototech has investigated this technology in a series of projects initiated by ESA focusing on both the essential fuel cell technology, demonstration of cycle performance of a RFCS, corresponding to 15 years in orbit, as well as the very important reactants storage systems. In the last two years the development has been focused towards optimising the key elements of the RFCS; the HTPEM fuel cell and the High Pressure PEM electrolyser. In these ESA activities the main target has been to optimise the design by reducing the mass and at the same time improve the performance, thus increasing the specific energy. This paper will present the latest development, including the main results, showing that significant steps have been taken to increase TRL on these key components.

  20. Cellular Phone Towers, Maryland Transportation Authoirty leased cell towers, MDTA Cell Tower locations, Leased cell towers, Published in 2010, 1:1200 (1in=100ft) scale, Maryland Transportation Authority.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cellular Phone Towers dataset, published at 1:1200 (1in=100ft) scale, was produced all or in part from Hardcopy Maps information as of 2010. It is described as...