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Sample records for satellite control centre

  1. Satellite Attitude Control System Simulator

    Directory of Open Access Journals (Sweden)

    G.T. Conti

    2008-01-01

    Full Text Available Future space missions will involve satellites with great autonomy and stringent pointing precision, requiring of the Attitude Control Systems (ACS with better performance than before, which is function of the control algorithms implemented on board computers. The difficulties for developing experimental ACS test is to obtain zero gravity and torque free conditions similar to the SCA operate in space. However, prototypes for control algorithms experimental verification are fundamental for space mission success. This paper presents the parameters estimation such as inertia matrix and position of mass centre of a Satellite Attitude Control System Simulator (SACSS, using algorithms based on least square regression and least square recursive methods. Simulations have shown that both methods have estimated the system parameters with small error. However, the least square recursive methods have performance more adequate for the SACSS objectives. The SACSS platform model will be used to do experimental verification of fundamental aspects of the satellite attitude dynamics and design of different attitude control algorithm.

  2. CANDU 9 Control Centre Mockup

    International Nuclear Information System (INIS)

    Webster, A.; Macbeth, M.J.

    1996-01-01

    This paper provides a summary of the design process being followed, the benefits of applying a systematic design using human factors engineering, presents an overview of the CANDU 9 control centre mockup facility, illustrates the control centre mockup with photographs of the 3D CADD model and the full scale mockup, and provides an update on the current status of the project. (author)

  3. Council celebrates CERN Control Centre

    CERN Multimedia

    2006-01-01

    With the unveiling of its new sign, the CERN Control Centre was officially inaugurated on Thursday 16 March. To celebrate its startup, CERN Council members visited the sleek centre, a futuristic-looking room filled with a multitude of monitoring screens.

  4. Satellite Control Laboratory

    DEFF Research Database (Denmark)

    Wisniewski, Rafal; Bak, Thomas

    2001-01-01

    The Satellite Laboratory at the Department of Control Engineering of Aalborg University (SatLab) is a dynamic motion facility designed for analysis and test of micro spacecraft. A unique feature of the laboratory is that it provides a completely gravity-free environment. A test spacecraft......-axis magnetometer, three piezoelectric gyros, and four reaction wheels in a tetrahedron configuration. The operation of the spacecraft is fully autonomous. The data flow between the transducers and the onboard computer placed physically outside the satellite is provided by a radio link. The purpose...... can be implemented in the laboratory, e.g. three-axis attitude control, slew manoeuvres, spins stabilization using magnetic actuation and/or reaction wheels. The spacecraft attitude can be determined applying magnetometer measurements....

  5. Satellite Control Laboratory

    DEFF Research Database (Denmark)

    Wisniewski, Rafal; Bak, Thomas

    2001-01-01

    The Satellite Laboratory at the Department of Control Engineering of Aalborg University (SatLab) is a dynamic motion facility designed for analysis and test of micro spacecraft. A unique feature of the laboratory is that it provides a completely gravity-free environment. A test spacecraft...... of the laboratory is to conduct dynamic tests of the control and attitude determination algorithms during nominal operation and in abnormal conditions. Further it is intended to use SatLab for validation of various algorithms for fault detection, accommodation and supervisory control. Different mission objectives...... can be implemented in the laboratory, e.g. three-axis attitude control, slew manoeuvres, spins stabilization using magnetic actuation and/or reaction wheels. The spacecraft attitude can be determined applying magnetometer measurements...

  6. Agent control of cooperating satellites

    OpenAIRE

    Lincoln, N.K.; Veres, S.M.; Dennis, Louise; Fisher, Michael; Lisitsa, Alexei

    2011-01-01

    A novel, hybrid, agent architecture for (small)swarms of satellites has been developed. The software architecture for each satellite comprises ahigh-level rational agent linked to a low-level control system. The rational agent forms dynamicgoals, decides how to tackle them and passes theactual implementation of these plans to the control layer. The rational agent also has access to aMatLabmodel of the satellite dynamics, thus allowing it to carry out selective hypothetical reasoningabout pote...

  7. The new AMS control centre

    CERN Multimedia

    Anaïs Schaeffer

    2011-01-01

    Construction work for the future AMS control room began in November 2010 and should be finished this June. The new building, which will have been completed in record time thanks to the professionalism of the project team, will soon be ready to receive the initial data from the AMS experiment.     Luigi Scibile and Michael Poehler, from the GS department, at the AMS control centre construction site.   The Alpha Magnetic Spectrometer (AMS) is due to wing its way towards the International Space Station (ISS) on board the shuttle Discovery in April. Mainly intended for research on antimatter and dark matter, the data collected by AMS will be sent to Houston in the United States and then directly to CERN’s new Building 946. Construction work for the AMS control centre building on the Route Gentner at CERN’s Prévessin site started in November 2010 and must be completed in time to receive the first data from the spectrometer in June. “It normall...

  8. CCS-MIP: Low cost Customizable Control Centre

    Science.gov (United States)

    Labezin, Christian; Vielcanet, Pierre

    1994-01-01

    The positioning and station keeping of French national satellites are among the main missions of CNES French Space Agency CNES. The related experience and skills of the Toulouse Space Centre are reknown and often required at international level for a wide range of missions. CISI, a software engineering company, has been contributing during the last 20 years to the development of the French space programs, particularly in the field of space missions ground control segments. The CCS-MIP system, presented here, is a satellite positioning and station-keeping system designed to answer the CNES multi-mission needs, easily adaptable for a wide range of applications.

  9. A day in the CERN Control Centre

    CERN Multimedia

    Rosaria Marraffino

    2015-01-01

    The CERN Control Centre (CCC) is the nerve centre of the CERN beam systems. From this room, the experts prepare, monitor, adjust, and control the particle beams that circulate throughout the accelerator complex while ensuring that the services and the technical infrastructure work flawlessly. Buttons, screens, telephones, lights (but no sound): in the CCC, everything is ready to make it possible for the LHC to reach the unprecedented energies expected at Run 2.   Seen from above, the CERN Control Centre resembles the shape of a quadrupole magnet. The consoles are distributed in four circles, called “islands”, dedicated to the LHC, the SPS, the PS Complex and the Technical Infrastructure (TI) respectively. Spread between TI and LHC are the Cryogenics consoles. Being in the same room allows the 24h-manned islands to be constantly in touch with one another, thus ensuring the best performance of the machines. At the LHC island, operators are currently busy training the magnet...

  10. Satellite Formation Control Using Atmospheric Drag

    National Research Council Canada - National Science Library

    Hajovsky, Blake B

    2007-01-01

    This study investigates the use of a linear quadratic terminal controller to reconfigure satellite formations using atmospheric drag actuated control while minimizing the loss of energy of the formation...

  11. Enhancing Safety at Airline Operations Control Centre

    Directory of Open Access Journals (Sweden)

    Lukáš Řasa

    2015-04-01

    Full Text Available In recent years a new term of Safety Management System (SMS has been introduced into aviation legislation. This system is being adopted by airline operators. One of the groundbased actors of everyday operations is Operations Control Centre (OCC. The goal of this article has been to identify and assess risks and dangers which occur at OCC and create a template for OCC implementation into SMS.

  12. Satellite Attitude Control Using Only Electromagnetic Actuation

    DEFF Research Database (Denmark)

    Wisniewski, Rafal

    when a satellite is on a throughout this thesis. Confined computer capacity and a limit on electrical power supply were separate obstacles.They demanded computational simplicity and power optimality from the attitude control system. The design of quasi optimal controllers for a real-time implementation...... to provide four stable equilibria, one of which was the desired orientation. It was explained how the equilibria depended on the ratio of the satellite's moments of inertia. It was further investigated how to control the attitude, such that the satellite was globally asymptotically stable in the desired...

  13. Control of the Tevatron Satellite Refrigeration system

    International Nuclear Information System (INIS)

    Theilacker, J.; Chapman, L.; Gannon, J.; Hentges, M.; Martin, M.; Rode, C.H.; Zagel, J.

    1984-01-01

    This chapter describes a computerized control system for 24 satellite refrigerators which cool a six kilometer ring of superconducting magnets. The control system consists of 31 independent microprocessors operating over 400 servo loops, and a central computer system which provides monitoring, alarms, logging and changing of parameters. Topics considered include pressure measurement, flow measurement, temperature measurement, gas analysis, control valves, expansion engine controllers, and control loops. Each refrigerator has 12 active microprocessor based control loops which tune the refrigerator to one of its four operating modes: satellite, liquefier, refrigerator, and stand-by. It is suggested that optimizing the refrigerator control loops and quench recovery scheme will minimize the accelerator down time

  14. Congestion control and routing over satellite networks

    Science.gov (United States)

    Cao, Jinhua

    Satellite networks and transmissions find their application in fields of computer communications, telephone communications, television broadcasting, transportation, space situational awareness systems and so on. This thesis mainly focuses on two networking issues affecting satellite networking: network congestion control and network routing optimization. Congestion, which leads to long queueing delays, packet losses or both, is a networking problem that has drawn the attention of many researchers. The goal of congestion control mechanisms is to ensure high bandwidth utilization while avoiding network congestion by regulating the rate at which traffic sources inject packets into a network. In this thesis, we propose a stable congestion controller using data-driven, safe switching control theory to improve the dynamic performance of satellite Transmission Control Protocol/Active Queue Management (TCP/AQM) networks. First, the stable region of the Proportional-Integral (PI) parameters for a nominal model is explored. Then, a PI controller, whose parameters are adaptively tuned by switching among members of a given candidate set, using observed plant data, is presented and compared with some classical AQM policy examples, such as Random Early Detection (RED) and fixed PI control. A new cost detectable switching law with an interval cost function switching algorithm, which improves the performance and also saves the computational cost, is developed and compared with a law commonly used in the switching control literature. Finite-gain stability of the system is proved. A fuzzy logic PI controller is incorporated as a special candidate to achieve good performance at all nominal points with the available set of candidate controllers. Simulations are presented to validate the theory. An effocient routing algorithm plays a key role in optimizing network resources. In this thesis, we briefly analyze Low Earth Orbit (LEO) satellite networks, review the Cross Entropy (CE

  15. The CERN Control Centre is up and running!

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    The CERN Control Centre (CCC) that combines all the control rooms for the accelerators, the cryogenic system and the technical infrastructure came into operation on 1st February. On 1st February, at 2.00 p.m., Patrick Villeton Pachot started the first Technical Infrastructure shift at the brand new CERN Control Centre.

  16. Small Satellite Passive Magnetic Attitude Control

    Science.gov (United States)

    Gerhardt, David T.

    Passive Magnetic Attitude Control (PMAC) is capable of aligning a satellite within 5 degrees of the local magnetic field at low resource cost, making it ideal for a small satellite. However, simulation attempts to date have not been able to predict the attitude dynamics at a level sufficient for mission design. Also, some satellites have suffered from degraded performance due to an incomplete understanding of PMAC system design. This dissertation alleviates these issues by discussing the design, inputs, and validation of PMAC systems for small satellites. Design rules for a PMAC system are defined using the Colorado Student Space Weather Experiment (CSSWE) CubeSat as an example. A Multiplicative Extended Kalman Filter (MEKF) is defined for the attitude determination of a PMAC satellite without a rate gyro. After on-orbit calibration of the off-the-shelf magnetometer and photodiodes and an on-orbit fit to the satellite magnetic moment, the MEKF regularly achieves a three sigma attitude uncertainty of 4 degrees or less. CSSWE is found to settle to the magnetic field in seven days, verifying its attitude design requirement. A Helmholtz cage is constructed and used to characterize the CSSWE bar magnet and hysteresis rods both individually and in the flight configuration. Fitted parameters which govern the magnetic material behavior are used as input to a PMAC dynamics simulation. All components of this simulation are described and defined. Simulation-based dynamics analysis shows that certain initial conditions result in abnormally decreased settling times; these cases may be identified by their dynamic response. The simulation output is compared to the MEKF output; the true dynamics are well modeled and the predicted settling time is found to possess a 20 percent error, a significant improvement over prior simulation.

  17. Intrinsic alignment in redMaPPer clusters - II. Radial alignment of satellites towards cluster centres

    Science.gov (United States)

    Huang, Hung-Jin; Mandelbaum, Rachel; Freeman, Peter E.; Chen, Yen-Chi; Rozo, Eduardo; Rykoff, Eli

    2018-03-01

    We study the orientations of satellite galaxies in redMaPPer clusters constructed from the Sloan Digital Sky Survey at 0.1 measurement methods (re-Gaussianization, de Vaucouleurs, and isophotal shapes), which trace galaxy light profiles at different radii. The measured SA signal depends on these shape measurement methods. We detect the strongest SA signal in isophotal shapes, followed by de Vaucouleurs shapes. While no net SA signal is detected using re-Gaussianization shapes across the entire sample, the observed SA signal reaches a statistically significant level when limiting to a subsample of higher luminosity satellites. We further investigate the impact of noise, systematics, and real physical isophotal twisting effects in the comparison between the SA signal detected via different shape measurement methods. Unlike previous studies, which only consider the dependence of SA on a few parameters, here we explore a total of 17 galaxy and cluster properties, using a statistical model averaging technique to naturally account for parameter correlations and identify significant SA predictors. We find that the measured SA signal is strongest for satellites with the following characteristics: higher luminosity, smaller distance to the cluster centre, rounder in shape, higher bulge fraction, and distributed preferentially along the major axis directions of their centrals. Finally, we provide physical explanations for the identified dependences and discuss the connection to theories of SA.

  18. Multi-technology control centre to integrate 460 MW renewables

    International Nuclear Information System (INIS)

    2016-01-01

    The new RWE Innogy Aersa Control Centre that has been certified to act as an interface with CECRE (the Renewable Energy Control Centre) since February 2015, connects RWE’s 20 renewable energy facilities with REE, the Spanish Electricity Grid. As a result, it ensures that wind farms, in addition to hydropower and solar plants, can inject the energy generated by its 460 MW installed safely and with no penalties. Green Eagle Solutions, a provider of software solutions for renewable energy companies, has collaborated with RWE in the development of this Control Centre, meeting the high standards of quality and safety required by RWE. This centre uses CompactSCADA® technology to integrate power generation facilities that need to be integrated in a Control Centre to communicate with REE’s CECRE. (Author)

  19. Partially Decentralized Control Architectures for Satellite Formations

    Science.gov (United States)

    Carpenter, J. Russell; Bauer, Frank H.

    2002-01-01

    In a partially decentralized control architecture, more than one but less than all nodes have supervisory capability. This paper describes an approach to choosing the number of supervisors in such au architecture, based on a reliability vs. cost trade. It also considers the implications of these results for the design of navigation systems for satellite formations that could be controlled with a partially decentralized architecture. Using an assumed cost model, analytic and simulation-based results indicate that it may be cheaper to achieve a given overall system reliability with a partially decentralized architecture containing only a few supervisors, than with either fully decentralized or purely centralized architectures. Nominally, the subset of supervisors may act as centralized estimation and control nodes for corresponding subsets of the remaining subordinate nodes, and act as decentralized estimation and control peers with respect to each other. However, in the context of partially decentralized satellite formation control, the absolute positions and velocities of each spacecraft are unique, so that correlations which make estimates using only local information suboptimal only occur through common biases and process noise. Covariance and monte-carlo analysis of a simplified system show that this lack of correlation may allow simplification of the local estimators while preserving the global optimality of the maneuvers commanded by the supervisors.

  20. Vibration noise control in laser satellite communication

    Science.gov (United States)

    Saksonov, Avigdor; Shlomi, Arnon; Kopeika, Norman S.

    2001-08-01

    Laser satellite communication has become especially attractive in recent years. Because the laser beam width is narrow than in the RF or microwave range, the transmitted optical power may be significantly reduced. This leads to development of miniature communication systems with extremely low power consumption. On the other hand, the laser communication channel is very sensitive to vibrations of the optical platform. These vibrations cause angular noise in laser beam pointing, comparable to the laser beam width. As result, as significant portion of the optical power between transmitter and receiver is lost and the bit error rate is increased. Consequently, vibration noise control is a critical problem in laser satellite communication. The direction of the laser beam is corrected with a fast steering mirror (FSM). In this paper are presented two approaches for the FSM control. One is the feedback control that uses an LQG algorithm. The second is the direct feed- forward control when vibration noise is measured by three orthogonal accelerometers and drives directly the F SM. The performances of each approach are evaluated using MATLAB simulations.

  1. The CERN Control Centre is up and running!

    CERN Multimedia

    2006-01-01

    The CERN Control Centre (CCC) that combines all the control rooms for the accelerators, the cryogenic system and the technical infrastructure came into operation on 1st February. This is not a mock-up but the real thing! The CERN Control Centre has been built and put into operation in only 15 months.On 1st February, at 2.00 p.m., Patrick Villeton Pachot started the first Technical Infrastructure shift at the brand new CERN Control Centre. From now on, when you dial 72201 to report a leak or an electrical fault, your call will ring out in the brand new CERN Control Centre. The much anticipated CCC came on line on 1st February, exactly as planned. The 2.00 p.m. shift by the operators of the former Technical Control Room (TCR), now renamed TI for Technical Infrastructure, marked the start of operations at the Centre. The PCR, MCR, TCR and QCR are no more, and all the individual control rooms have been merged into one. And what a control room it is! True to the streamlined image announced when the project was f...

  2. A demand assignment control in international business satellite communications network

    Science.gov (United States)

    Nohara, Mitsuo; Takeuchi, Yoshio; Takahata, Fumio; Hirata, Yasuo

    An experimental system is being developed for use in an international business satellite (IBS) communications network based on demand-assignment (DA) and TDMA techniques. This paper discusses its system design, in particular from the viewpoints of a network configuration, a DA control, and a satellite channel-assignment algorithm. A satellite channel configuration is also presented along with a tradeoff study on transmission rate, HPA output power, satellite resource efficiency, service quality, and so on.

  3. Relative tracking control of constellation satellites considering inter-satellite link

    Science.gov (United States)

    Fakoor, M.; Amozegary, F.; Bakhtiari, M.; Daneshjou, K.

    2017-11-01

    In this article, two main issues related to the large-scale relative motion of satellites in the constellation are investigated to establish the Inter Satellite Link (ISL) which means the dynamic and control problems. In the section related to dynamic problems, a detailed and effective analytical solution is initially provided for the problem of satellite relative motion considering perturbations. The direct geometric method utilizing spherical coordinates is employed to achieve this solution. The evaluation of simulation shows that the solution obtained from the geometric method calculates the relative motion of the satellite with high accuracy. Thus, the proposed analytical solution will be applicable and effective. In the section related to control problems, the relative tracking control system between two satellites will be designed in order to establish a communication link between the satellites utilizing analytical solution for relative motion of satellites with respect to the reference trajectory. Sliding mode control approach is employed to develop the relative tracking control system for body to body and payload to payload tracking control. Efficiency of sliding mode control approach is compared with PID and LQR controllers. Two types of payload to payload tracking control considering with and without payload degree of freedom are designed and suitable one for practical ISL applications is introduced. Also, Fuzzy controller is utilized to eliminate the control input in the sliding mode controller.

  4. Control of peripheral units by satellite computer

    International Nuclear Information System (INIS)

    Tran, K.T.

    1974-01-01

    A computer system was developed allowing the control of nuclear physics experiments, and use of the results by means of graphical and conversational assemblies. This system which is made of two computers, one IBM-370/135 and one Telemecanique Electrique T1600, controls the conventional IBM peripherals and also the special ones made in the laboratory, such as data acquisition display and graphics units. The visual display is implemented by a scanning-type television, equipped with a light-pen. These units in themselves are universal, but their specifications were established to meet the requirements of nuclear physics experiments. The input-output channels of the two computers have been connected together by an interface, designed and implemented in the Laboratory. This interface allows the exchange of control signals and data (the data are changed from bytes into word and vice-versa). The T1600 controls the peripherals mentionned above according to the commands of the IBM370. Hence the T1600 has here the part of a satellite computer which allows conversation with the main computer and also insures the control of its special peripheral units [fr

  5. Determination of the centre of mass kinematics in alpine skiing using differential global navigation satellite systems.

    Science.gov (United States)

    Gilgien, Matthias; Spörri, Jörg; Chardonnens, Julien; Kröll, Josef; Limpach, Philippe; Müller, Erich

    2015-01-01

    In the sport of alpine skiing, knowledge about the centre of mass (CoM) kinematics (i.e. position, velocity and acceleration) is essential to better understand both performance and injury. This study proposes a global navigation satellite system (GNSS)-based method to measure CoM kinematics without restriction of capture volume and with reasonable set-up and processing requirements. It combines the GNSS antenna position, terrain data and the accelerations acting on the skier in order to approximate the CoM location, velocity and acceleration. The validity of the method was assessed against a reference system (video-based 3D kinematics) over 12 turn cycles on a giant slalom skiing course. The mean (± s) position, velocity and acceleration differences between the CoM obtained from the GNSS and the reference system were 9 ± 12 cm, 0.08 ± 0.19 m · s(-1) and 0.22 ± 1.28 m · s(-2), respectively. The velocity and acceleration differences obtained were smaller than typical differences between the measures of several skiers on the same course observed in the literature, while the position differences were slightly larger than its discriminative meaningful change. The proposed method can therefore be interpreted to be technically valid and adequate for a variety of biomechanical research questions in the field of alpine skiing with certain limitations regarding position.

  6. Development of the Advanced CANDU Reactor control centre

    International Nuclear Information System (INIS)

    Malcolm, S.; Leger, R.

    2004-01-01

    The next generation CANDU control centre is being designed for the Advanced CANDU Reactor (ACR) station. The design is based upon the recent Qinshan control room with further upgrades to meet customer needs with respect to high capacity factor with low Operation, Maintenance and Administration (OM and A) costs. This evolutionary design includes the long proven functionality at several existing CANDU control centres such as the 4-unit station at Darlington, with advanced features made possible by new control and display technology. Additionally, ACR control centres address characteristics resulting from Human Factors Engineering (HFE) analysis of control centre operations in order to further enhance personnel awareness of system and plant status. Statistics show that up to 70% of plant significant events, which have caused plant outages, have a root cause attributable to the human from such sources as complex interfaces, procedures, maintenance and management practices. Consequently, special attention is made for the application of HFE throughout the ACR design process. The design process follows a systematic analytical approach to define operations staff information and information presentation requirements. The resultant human-system interfaces (HSI) such as those for monitoring, annunciation and control information are then verified and validated against the system design requirements to provide a high confidence level that adequate and correct information is being provided in a timely manner to support the necessary operational tasks. The ACR control centre provides plant staff with an improved operability capability due to the combination of systematic design and enhanced operating features. Significant design processes (i.e. development) or design features which contribute to this improved operability, include: Design Process: Project HFE Program Plan - intent, scope, timeliness and interfacing; HFE aspects of design process - procedures and instructions

  7. Development of the advanced CANDU reactor control centre

    International Nuclear Information System (INIS)

    Malcolm, S.; Leger, R.

    2004-01-01

    The next generation CANDU control centre is being designed for the Advanced CANDU Reactor (ACR) station. The design is based upon the recent Qinshan control room with further upgrades to meet customer needs with respect to high capacity factor with low Operation, Maintenance and Administration (OM and A) costs. This evolutionary design includes the long proven functionality at several existing CANDU control centres such as the 4-unit station at Darlington, with advanced features made possible by new control and display technology. Additionally, ACR control centres address characteristics resulting from Human Factors Engineering (HFE) analysis of control centre operations in order to further enhance personnel awareness of system and plant status. Statistics show that up to 70% of plant significant events, which have caused plant outages, have a root cause attributable to the human from such sources as complex interfaces, procedures, maintenance and management practices. Consequently, special attention is made for the application of HFE throughout the ACR design process. The design process follows a systematic analytical approach to define operations staff information and information presentation requirements. The resultant human-system interfaces (HSI) such as those for monitoring, annunciation and control information are then verified and validated against the system design requirements to provide a high confidence level that adequate and correct information is being provided in a timely manner to support the necessary operational tasks. The ACR control centre provides plant staff with an improved operability capability due to the combination of systematic design and enhanced operating features. Significant design processes (i.e. development) or design features which contribute to this improved operability, include: Design Process: Project HFE Program Plan - intent, scope, timeliness and interfacing; HFE aspects of design process - procedures and instructions

  8. Programming a real-time operating system for satellite control applications Satellite Control Applications

    International Nuclear Information System (INIS)

    Omer, M.; Anjum, O.; Suddle, M.R.

    2004-01-01

    With the realization of ideas like formation flights and multi-body space vehicles the demands on an attitude control system have become increasingly complex. Even in its most simplified form, the control system for a typical geostationary satellite has to run various supervisory functions along with determination and control algorithms side by side. Within each algorithm it has to employ multiple actuation and sensing mechanisms and service real time interrupts, for example, in the case of actuator saturation and sensor data fusion. This entails the idea of thread scheduling and program synchronization, tasks specifically meant for a real time OS. This paper explores the embedding of attitude determination and control loop within the framework of a real time operating system provided for TI's DSP C6xxx series. The paper details out the much functionality provided within the scaleable real time kernel and the analysis and configuration tools available, It goes on to describe a layered implementation stack associated with a typical control for Geo Stationary satellites. An application for control is then presented in which state of the art analysis tools are employed to view program threads, synchronization semaphores, hardware interrupts and data exchange pipes operating in real time. (author)

  9. Modeling and control of a gravity gradient stabilised satellite

    Directory of Open Access Journals (Sweden)

    Aage Skullestad

    1999-01-01

    Full Text Available This paper describes attitude control, i.e., 3-axes stabilisation and pointing, of a proposed Norwegian small gravity gradient stabilized satellite to be launched into low earth orbit. Generally, a gravity gradient stabilised system has limited stability and pointing capabilities, and wheels and/or magnetic coils are added in order to improve the attitude control. The best attitude accuracy is achieved using wheels, which can give accuracies down to less than one degree, but wheels increase the complexity and cost of the satellite. Magnetic coils allow cheaper satellites, and are an attractive solution to small, inexpensive satellites in low earth orbits and may provide an attitude control accuracy of a few degrees. Scientific measurements often require accurate attitude control in one or two axes only. Combining wheel and coil control may, in these cases, provide the best solutions. The simulation results are based on a linearised mathematical model of the satellite.

  10. A computer simulation of the new Control Centre (CCC)

    CERN Multimedia

    2004-01-01

    In a development crucial for the success of the LHC, CERN will build a Control Centre (CCC) for the operation of all its beams and accelerators. The CCC will be an extension of the existing PCR building at Prévessin and is due to be operational by 1 February 2006.

  11. Fuzzy Logic Controller for Small Satellites Navigation

    National Research Council Canada - National Science Library

    Della Pietra, G; Falzini, S; Colzi, E; Crisconio, M

    2005-01-01

    .... The navigator aims at operating satellites in orbit with a minimum ground support and very good performances, by the adoption of innovative technologies, such as attitude observation GPS, attitude...

  12. Complete quantum control of exciton qubits bound to isoelectronic centres.

    Science.gov (United States)

    Éthier-Majcher, G; St-Jean, P; Boso, G; Tosi, A; Klem, J F; Francoeur, S

    2014-05-30

    In recent years, impressive demonstrations related to quantum information processing have been realized. The scalability of quantum interactions between arbitrary qubits within an array remains however a significant hurdle to the practical realization of a quantum computer. Among the proposed ideas to achieve fully scalable quantum processing, the use of photons is appealing because they can mediate long-range quantum interactions and could serve as buses to build quantum networks. Quantum dots or nitrogen-vacancy centres in diamond can be coupled to light, but the former system lacks optical homogeneity while the latter suffers from a low dipole moment, rendering their large-scale interconnection challenging. Here, through the complete quantum control of exciton qubits, we demonstrate that nitrogen isoelectronic centres in GaAs combine both the uniformity and predictability of atomic defects and the dipole moment of semiconductor quantum dots. This establishes isoelectronic centres as a promising platform for quantum information processing.

  13. Satellites

    International Nuclear Information System (INIS)

    Burns, J.A.; Matthews, M.S.

    1986-01-01

    The present work is based on a conference: Natural Satellites, Colloquium 77 of the IAU, held at Cornell University from July 5 to 9, 1983. Attention is given to the background and origins of satellites, protosatellite swarms, the tectonics of icy satellites, the physical characteristics of satellite surfaces, and the interactions of planetary magnetospheres with icy satellite surfaces. Other topics include the surface composition of natural satellites, the cratering of planetary satellites, the moon, Io, and Europa. Consideration is also given to Ganymede and Callisto, the satellites of Saturn, small satellites, satellites of Uranus and Neptune, and the Pluto-Charon system

  14. High Precision Control of Ship-Mounted Satellite Tracking Antenna

    DEFF Research Database (Denmark)

    Mohsen, Soltani; Izadi-Zamanabadi, Roozbeh; Wisniewski, Rafal

    2007-01-01

    The telecommunication on a modern merchandise ship is maintained by means of satellite communication. The task of the tracking system is to position the on-board antenna toward a chosen satellite. The control system is capable of rejecting the external disturbances which affect on the under...

  15. Evolution of the CANDU control centre retrofit and new stations

    International Nuclear Information System (INIS)

    Olmstead, R.A.; Mitchell, W.

    1991-01-01

    Significant event data from operating nuclear plants in many countries consistently indicates human errors are the root cause for 40-60% of operating station significant events. Because so much information is already in digital form, opportunities exist to improve the CANDU control centre with retrofits that exploit this information. These opportunities are enhanced because of rapid technological development in computers and electronics, coupled with significant progress in the behavioural sciences that greatly increases our knowledge of the cognitive strengths and weaknesses of human beings. CANDU control rooms are undergoing retrofits and for future CANDU stations, a new concept of the control centre is emerging. The objective is to significantly reduce the incidence of human error, reduce operations and maintenance costs and improve both reliability and safety

  16. Evolution of the CANDU control centre retrofit and new stations

    Energy Technology Data Exchange (ETDEWEB)

    Olmstead, R A [AECL-CANDU, ON (Canada); Mitchell, W [Ontario Hydro, Darlington Nuclear Generating Station, Bowmanville, ON (Canada)

    1991-04-01

    Significant event data from operating nuclear plants in many countries consistently indicates human errors are the root cause for 40-60% of operating station significant events. Because so much information is already in digital form, opportunities exist to improve the CANDU control centre with retrofits that exploit this information. These opportunities are enhanced because of rapid technological development in computers and electronics, coupled with significant progress in the behavioural sciences that greatly increases our knowledge of the cognitive strengths and weaknesses of human beings. CANDU control rooms are undergoing retrofits and for future CANDU stations, a new concept of the control centre is emerging. The objective is to significantly reduce the incidence of human error, reduce operations and maintenance costs and improve both reliability and safety.

  17. New concepts of control centre design and development

    International Nuclear Information System (INIS)

    Dittmar, E.; Kiersch, J.J.; Schmudlach, U.; Weihrauch, J.

    1977-02-01

    The concept of modern control centre technology is shown, its realization at project including the supervision of an electric power distribution system is described. A modern control centre is characterized by the fact that the conventional control elements are more and more replaced by elements of computer technology, i.e. computer and displays. The different functions implemented by hard- and software set new standards relative to flexibility, adaptability, dimensioning. The communication interface man/process is defined and designed in a new way allowing dynamic and more efficent supervisionstrategy of technical processes via display in different operation modes. Special attention is paid to adjustments and extensions of process elements and their integration into the supervised network. (orig./WB) [de

  18. The artificial satellite observation chronograph controlled by single chip microcomputer.

    Science.gov (United States)

    Pan, Guangrong; Tan, Jufan; Ding, Yuanjun

    1991-06-01

    The instrument specifications, hardware structure, software design, and other characteristics of the chronograph mounting on a theodolite used for artificial satellite observation are presented. The instrument is a real time control system with a single chip microcomputer.

  19. Improved operability of the CANDU 9 control centre

    International Nuclear Information System (INIS)

    Macbeth, M. J.; Webster, A.

    1996-01-01

    The next generation CANDU nuclear power plant being designed by AECL is the 900 MWe class CANDU 9 station. It is based upon the Darlington CANDU station design which is among the world leaders in capacity factor with low Operation, Maintenance and Administration (OM and A) costs. This Control Centre design includes the proven functionality of existing CANDU control centres (including the Wolsong 2,3, and 4 control centre improvements, such as the Emergency Core Cooling panels), the characteristics identified by systematic design with human factors analysis of operations requirements and the advanced features needed to improve station operability which is made possible by the application of new technology. The CANDU 9 Control Centre provides plant staff with an improved operability capability due to the combination of proveness, systematic design with human factors engineering and enhanced operating features. Significant features which contribute to this improved operability include: · Standard NSP, BOP and F/H panels with controls and indicators integrated by a standard display/presentation philosophy. · Common plant parameter signal database for extensive monitoring, checking, display and annunciation. · Powerful annunciation system allowing alarm filtering, prioritizing and interrogation to enhance staff recognition of events, plant state and required corrective procedural actions. · The use of an overview display to present immediate and uncomplicated plant status information to facilitate operator awareness of unit status in a highly readable and recognizable format. · Extensive cross checking of similar process parameters amongst themselves, with the counterpart safety system parameters and as well as with 'signature' values obtained from known steady state conditions. · Powerful calculation capabilities, using the plant wide database, providing immediate recognizable and readable and readable output data on plant state information and plant state change

  20. Satellite cluster flight using on-off cyclic control

    Science.gov (United States)

    Zhang, Hao; Gurfil, Pini

    2015-01-01

    Nano-satellite clusters and disaggregated satellites are new concepts in the realm of distributed satellite systems, which require complex cluster management - mainly regulating the maximal and minimal inter-satellite distances on time scales of years - while utilizing simple on-off propulsion systems. The simple actuators and long time scales require judicious astrodynamical modeling coupled with specialized orbit control. This paper offers a satellite cluster orbit control law which works for long time scales in a perturbed environment while utilizing fixed-magnitude thrusters. The main idea is to design a distributed controller which balances the fuel consumption among the satellites, thus mitigating the effect of differential drag perturbations. The underlying methodology utilizes a cyclic control algorithm based on a mean orbital elements feedback. Stability properties of the closed-loop cyclic control system do not adhere to the classical Lyapunov stability theory, so an effort is made to define and implement a suitable stability theory of noncompact equilibria sets. A state selection scheme is proposed for efficiently establishing a low Earth orbit cluster. Several simulations, including a real mission study, and several comparative investigations, are performed to show the strengths of the proposed control law.

  1. Sliding Mode Attitude Control for Magnetic Actuated Satellite

    DEFF Research Database (Denmark)

    Wisniewski, Rafal

    1998-01-01

    control torques can only be generated perpendicular to the local geomagnetic field vector. This has been a serious obstacle for using magnetorquer based control for three-axis attitude control. This paper deals with three-axis stabilization of a low earth orbit satellite. The problem of controlling...... the spacecraft attitude using only magnetic torquing is realized in the form of the sliding mode control. A three dimensional sliding manifold is proposed, and it is shown that the satellite motion on the sliding manifold is asymptotically stable...

  2. Integrated control centre concepts for CANDU power plants

    International Nuclear Information System (INIS)

    Lupton, L.R.; Davey, E.C.; Lapointe, P.A.; Shah, R.R.

    1990-01-01

    The size and complexity of nuclear power plants has increased significantly in the last 20 years. There is general agreement that plant safety and power production can be enhanced if more operational support systems that are significantly different from the ones based on the more conventional technologies used in plant control rooms. In particular, artificial intelligence and related technologies will play a major role in the development of innovative methods for information processing and presentation. These technologies must be integrated into the overall management and control philosophy of the plant and not be treated as vehicles to implement point solutions. The underlying philosophy behind our approach is discussed in this paper. Operator support systems will integrate into the overall control philosophy by complementing the operator. Four support systems are described; each is a prototype of a system being considered for the CANDU 3 control centre

  3. Integrated control centre concepts for CANDU power plants

    Energy Technology Data Exchange (ETDEWEB)

    Lupton, L. R.; Davey, E. C.; Lapointe, P. A.; Shah, R. R.

    1990-01-15

    The size and complexity of nuclear power plants has increased significantly in the last 20 years. There is general agreement that plant safety and power production can be enhanced if more operational support systems that are significantly different from the ones based on the more conventional technologies used in plant control rooms. In particular, artificial intelligence and related technologies will play a major role in the development of innovative methods for information processing and presentation. These technologies must be integrated into the overall management and control philosophy of the plant and not be treated as vehicles to implement point solutions. The underlying philosophy behind our approach is discussed in this paper. Operator support systems will integrate into the overall control philosophy by complementing the operator. Four support systems are described; each is a prototype of a system being considered for the CANDU 3 control centre.

  4. Attitude Control Subsystem for the Advanced Communications Technology Satellite

    Science.gov (United States)

    Hewston, Alan W.; Mitchell, Kent A.; Sawicki, Jerzy T.

    1996-01-01

    This paper provides an overview of the on-orbit operation of the Attitude Control Subsystem (ACS) for the Advanced Communications Technology Satellite (ACTS). The three ACTS control axes are defined, including the means for sensing attitude and determining the pointing errors. The desired pointing requirements for various modes of control as well as the disturbance torques that oppose the control are identified. Finally, the hardware actuators and control loops utilized to reduce the attitude error are described.

  5. A Robust Controller Structure for Pico-Satellite Applications

    DEFF Research Database (Denmark)

    Kragelund, Martin Nygaard; Green, Martin; Kristensen, Mads

    This paper describes the development of a robust controller structure for use in pico-satellite missions. The structure relies on unknown disturbance estimation and use of robust control theory to implement a system that is robust to both unmodeled disturbances and parameter uncertainties. As one...

  6. Satellite Dynamic Damping via Active Force Control Augmentation

    Science.gov (United States)

    Varatharajoo, Renuganth

    2012-07-01

    An approach that incorporates the Active Force Control (AFC) technique into a conventional Proportional-Derivative (PD) controller is proposed for a satellite active dynamic damping towards a full attitude control. The AFC method has been established to facilitate a robust motion control of dynamical systems in the presence of disturbances, parametric uncertainties and changes that are commonly prevalent in the real-world environment. The usefulness of the method can be extended by introducing intelligent mechanisms to approximate the mass or inertia matrix of the dynamic system to trigger the compensation effect of the controller. AFC is a technique that relies on the appropriate estimation of the inertial or mass parameters of the dynamic system and the measurements of the acceleration and force signals induced by the system if practical implementation is ever considered. In AFC, it is shown that the system subjected to a number of disturbances remains stable and robust via the compensating action of the control strategy. We demonstrate that it is possible to design a spacecraft attitude feedback controller that will ensure the system dynamics set point remains unchanged even in the presence of the disturbances provided that the actual disturbances can be modeled effectively. In order to further facilitate this analysis, a combined energy and attitude control system (CEACS) is proposed as a model satellite attitude control actuator. All the governing equations are established and the proposed satellite attitude control architecture is made amenable to numerical treatments. The results show that the PD-AFC attitude damping performances are superiorly better than that of the solely PD type. It is also shown that the tunings of the AFC system gains are crucial to ensure a better attitude damping performance and this process is mandatory for AFC systems. Finally, the results demonstrate an important satellite dynamic damping enhancement capability using the AFC

  7. Application of digital control techniques for satellite medium power DC-DC converters

    Science.gov (United States)

    Skup, Konrad R.; Grudzinski, Pawel; Nowosielski, Witold; Orleanski, Piotr; Wawrzaszek, Roman

    2010-09-01

    The objective of this paper is to present a work concerning a digital control loop system for satellite medium power DC-DC converters that is done in Space Research Centre. The whole control process of a described power converter bases on a high speed digital signal processing. The paper presents a development of a FPGA digital controller for voltage mode stabilization that was implemented using VHDL. The described controllers are a classical digital PID controller and a bang-bang controller. The used converter for testing is a simple model of 5-20 W, 200 kHz buck power converter. A high resolution digital PWM approach is presented. Additionally a simple and effective solution of filtering of an analog-to-digital converter output is presented.

  8. The human factors specialist in nuclear control centre design

    International Nuclear Information System (INIS)

    Wilson, R.B.; Beattie, J.D.

    The main focus at Ontario Hydro for man-machine interface design is in the design of control centres. Because the control of a nuclear generating unit is highly centralized there is an increasing need for effective information display and control layout. Control panel design innovations such as the use of CRT displays and the extended use of computerized control in the Darlington station have made it possible for Ontario Hydro to continue to have one first operator for each generating unit. The human factors specialist involved in control panel design must deal with people who know much more about the specific systems being controlled, and must become a generalist in all these systems as well. Designers have to use conceptual techniques such as task analysis, systems design, panel mock-ups, anthropometric data, and personal judgement based on experience as they design panels. They must find a balance between becoming locked into existing technology and methods, slavishly following the latest technological trends, and forgetting that real people will be using what they design

  9. Direct Energy Centre underground parking integrated light control system

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-10-15

    LightSavers is a project undertaken by the Toronto Atmospheric Fund to accelerate the use of lighting technologies. As part of the project a pilot test has been carried out in the Direct Energy Center in Toronto. The aim of this report is to present the study and its results. The Direct Energy Center is a large event facility with an large underground parking facility. A lighting energy management system, the energy control system (ECS), capable of adjusting lighting levels based on occupancy was implemented in the centre and data was collected during over one year. Results showed that the ECS permitted a reduction in energy consumption and thus greenhouse gas emissions by 47% and the payback will take less than 6 years. This project demonstrated that the energy control system provides better energy, environmental and economic performance than a traditional automation system.

  10. Advanced Attitude Control af Pico Sized Satellites

    DEFF Research Database (Denmark)

    Larsen, Jesper A.; Amini, Rouzbeh; Izadi-Zamanabadi, Roozbeh

    2005-01-01

    accuracy of better than 5 degrees. Cost, size, weight and power requirements, on the other hand, impose selecting relative simple sensors and actuators which leads to an attitude control requirement of less than 1 degree. This precision is obtained by a combination of magnetorquers and momentum wheels...

  11. ACTS TDMA network control. [Advanced Communication Technology Satellite

    Science.gov (United States)

    Inukai, T.; Campanella, S. J.

    1984-01-01

    This paper presents basic network control concepts for the Advanced Communications Technology Satellite (ACTS) System. Two experimental systems, called the low-burst-rate and high-burst-rate systems, along with ACTS ground system features, are described. The network control issues addressed include frame structures, acquisition and synchronization procedures, coordinated station burst-time plan and satellite-time plan changes, on-board clock control based on ground drift measurements, rain fade control by means of adaptive forward-error-correction (FEC) coding and transmit power augmentation, and reassignment of channel capacities on demand. The NASA ground system, which includes a primary station, diversity station, and master control station, is also described.

  12. Satellite technology and the control of parasitic diseases in Africa ...

    African Journals Online (AJOL)

    The potential application of these techniques in the surveillance, control and prevention of parasitic diseases in Africa is explored in this write-up. Keywords: surveillance, parasitic diseases, satellite techniques, remote sensing, Geographical Information System (GIS), Global Positioning Sytem (GPS), human and robotic, ...

  13. 77 FR 70421 - GPS Satellite Simulator Control Working Group Meeting

    Science.gov (United States)

    2012-11-26

    ... DEPARTMENT OF DEFENSE Department of the Air Force GPS Satellite Simulator Control Working Group Meeting AGENCY: Space and Missile Systems Center, Global Positioning Systems (GPS) Directorate, Department of the Air Force, DoD. ACTION: Meeting Notice. SUMMARY: This meeting notice is to inform GPS...

  14. 78 FR 63459 - GPS Satellite Simulator Control Working Group Meeting

    Science.gov (United States)

    2013-10-24

    ... DEPARTMENT OF DEFENSE Air Force GPS Satellite Simulator Control Working Group Meeting AGENCY: Department of the Air Force. ACTION: Meeting Notice. SUMMARY: This meeting notice is to inform GPS simulator manufacturers, who supply products to the Department of Defense (DoD), and GPS simulator users, both government...

  15. 78 FR 67132 - GPS Satellite Simulator Control Working Group Meeting

    Science.gov (United States)

    2013-11-08

    ... DEPARTMENT OF DEFENSE Department of the Air Force GPS Satellite Simulator Control Working Group... simulator manufacturers, who supply products to the Department of Defense (DoD), and GPS simulator users..., and email address) to [email protected]us.af.mil and have your security personnel submit your VAR...

  16. Reliable Control of Ship-mounted Satellite Tracking Antenna

    DEFF Research Database (Denmark)

    Soltani, Mohsen; Izadi-Zamanabadi, Roozbeh; Wisniewski, Rafal

    2010-01-01

    Motorized antenna is a key element in overseas satellite telecommunication. The control system directs the on-board antenna toward a chosen satellitewhile the high sea waves disturb the antenna. Certain faults (communication system malfunction or signal blocking) cause interruption in the communi...

  17. Dynamics and chaos control of gyrostat satellite

    International Nuclear Information System (INIS)

    Aslanov, Vladimir; Yudintsev, Vadim

    2012-01-01

    Highlights: ► Free dual-spin gyrostat with a small rotor asymmetry is considered. ► Equations in Andoyer-Deprit canonical dimensionless variables are obtained. ► Phase space heteroclinic and homoclinic trajectories are written in closed form. ► Modified Melnikov function is used to construct the control that eliminates chaos. - Abstract: We consider the chaotic motion of the free gyrostat consisting of a platform with a triaxial inertia ellipsoid and a rotor with a small asymmetry with respect to the axis of rotation. Dimensionless equations of motion of the system with perturbations caused by small asymmetries of the rotor are written in Andoyer-Deprit variables. These perturbations lead to separatrix chaos. For gyrostats with different ratios of moments of inertia heteroclinic and homoclinic trajectories are written in closed-form. These trajectories are used for constructing modified Melnikov function, which is used for determine the control that eliminates separatrix chaos. Melnikov function and phase space trajectory are built to show the effectiveness of the control.

  18. Automatic charge control system for satellites

    Science.gov (United States)

    Shuman, B. M.; Cohen, H. A.

    1985-01-01

    The SCATHA and the ATS-5 and 6 spacecraft provided insights to the problem of spacecraft charging at geosychronous altitudes. Reduction of the levels of both absolute and differential charging was indicated, by the emission of low energy neutral plasma. It is appropriate to complete the transition from experimental results to the development of a system that will sense the state-of-charge of a spacecraft, and, when a predetermined threshold is reached, will respond automatically to reduce it. A development program was initiated utilizing sensors comparable to the proton electrostatic analyzer, the surface potential monitor, and the transient pulse monitor that flew in SCATHA, and combine these outputs through a microprocessor controller to operate a rapid-start, low energy plasma source.

  19. Attitude Control of a Satellite by using Digital Signal Processing

    Directory of Open Access Journals (Sweden)

    Adirelle C. Santana

    2012-03-01

    Full Text Available This article has discussed the development of a three-axis attitude digital controller for an artificial satellite using a digital signal processor. The main motivation of this study is the attitude control system of the satellite Multi-Mission Platform, developed by the Brazilian National Institute for Space Research for application in different sort of missions. The controller design was based on the theory of the Linear Quadratic Gaussian Regulator, synthesized from the linearized model of the motion of the satellite, i.e., the kinematics and dynamics of attitude. The attitude actuators considered in this study are pairs of cold gas jets powered by a pulse width/pulse frequency modulator. In the first stage of the project development, a system controller for continuous time was studied with the aim of testing the adequacy of the adopted control. The next steps had included an analysis of discretization techniques, the setting time of sampling rate, and the testing of the digital version of the Linear Quadratic Gaussian Regulator controller in the MATLAB/SIMULINK. To fulfill the study, the controller was implemented in a digital signal processor, specifically the Blackfin BF537 from Analog Devices, along with the pulse width/pulse frequency modulator. The validation tests used a scheme of co-simulation, where the model of the satellite was simulated in MATLAB/SIMULINK, while the controller and modulator were processed in the digital signal processor with a tool called Processor-In-the-Loop, which acted as a data communication link between both environments.function and required time to achieve a given mission accuracy are determined, and results are provided as illustration.

  20. An accountancy system for nuclear materials control in research centres

    International Nuclear Information System (INIS)

    Buttler, R.; Bueker, H.; Vallee, J.

    1979-01-01

    The Nuclear Accountancy and Control System (NACS) was developed at KFA Juelich in accordance with the requirements of the Non-Proliferation Treaty. The main features are (1) recording of nuclear material in inventory items. These are combined to form batches wherever suitable; (2) extrapolation of accounting data as a replacement for detailed measurement of inventory items data. Recording and control of nuclear material are carried out on two levels with access to a common data bank. The lower level deals with nuclear materials handling plus internal management while on the upper level there is a central control point which is responsible for nuclear safeguarding within the entire research centre. By keeping the organizational and technical infrastructure it was possible to develop a system which is both economical and operator-oriented. In this system the emphasis of nuclear safeguarding is placed on the acquisition of the nuclear material inventory. As much consideration has been given to the interests of the various operational levels and organizational units as to internal and national regulations. Since it is part of the safeguarding and control system, access to the NACS must be restricted to a limited number of users only. Furthermore, it must include facilities for manual control in the form of records. Authorization for access must correspond with the various tasks of different user groups. All necessary data are acquired decentrally in the organizational units and entered via a terminal. It is available to the user groups on both levels through a central data bank. To meet all requirements, the NACS has been designed as an integrated, computer-assisted information system for the automated processing of extensive and multi-level nuclear materials data. As part of the preventive measures entailed with nuclear safeguarding, the accountancy system enables the operator of a nuclear plant to furnish proof of non-diversion of nuclear material. (author)

  1. Integrated identification and control for nanosatellites reclaiming failed satellite

    Science.gov (United States)

    Han, Nan; Luo, Jianjun; Ma, Weihua; Yuan, Jianping

    2018-05-01

    Using nanosatellites to reclaim a failed satellite needs nanosatellites to attach to its surface to take over its attitude control function. This is challenging, since parameters including the inertia matrix of the combined spacecraft and the relative attitude information of attached nanosatellites with respect to the given body-fixed frame of the failed satellite are all unknown after the attachment. Besides, if the total control capacity needs to be increased during the reclaiming process by new nanosatellites, real-time parameters updating will be necessary. For these reasons, an integrated identification and control method is proposed in this paper, which enables the real-time parameters identification and attitude takeover control to be conducted concurrently. Identification of the inertia matrix of the combined spacecraft and the relative attitude information of attached nanosatellites are both considered. To guarantee sufficient excitation for the identification of the inertia matrix, a modified identification equation is established by filtering out sample points leading to ill-conditioned identification, and the identification performance of the inertia matrix is improved. Based on the real-time estimated inertia matrix, an attitude takeover controller is designed, the stability of the controller is analysed using Lyapunov method. The commanded control torques are allocated to each nanosatellite while the control saturation constraint being satisfied using the Quadratic Programming (QP) method. Numerical simulations are carried out to demonstrate the feasibility and effectiveness of the proposed integrated identification and control method.

  2. Groebner Basis Solutions to Satellite Trajectory Control by Pole Placement

    Science.gov (United States)

    Kukelova, Z.; Krsek, P.; Smutny, V.; Pajdla, T.

    2013-09-01

    Satellites play an important role, e.g., in telecommunication, navigation and weather monitoring. Controlling their trajectories is an important problem. In [1], an approach to the pole placement for the synthesis of a linear controller has been presented. It leads to solving five polynomial equations in nine unknown elements of the state space matrices of a compensator. This is an underconstrained system and therefore four of the unknown elements need to be considered as free parameters and set to some prior values to obtain a system of five equations in five unknowns. In [1], this system was solved for one chosen set of free parameters with the help of Dixon resultants. In this work, we study and present Groebner basis solutions to this problem of computation of a dynamic compensator for the satellite for different combinations of input free parameters. We show that the Groebner basis method for solving systems of polynomial equations leads to very simple solutions for all combinations of free parameters. These solutions require to perform only the Gauss-Jordan elimination of a small matrix and computation of roots of a single variable polynomial. The maximum degree of this polynomial is not greater than six in general but for most combinations of the input free parameters its degree is even lower. [1] B. Palancz. Application of Dixon resultant to satellite trajectory control by pole placement. Journal of Symbolic Computation, Volume 50, March 2013, Pages 79-99, Elsevier.

  3. New flexible thermal control material for long-life satellite

    International Nuclear Information System (INIS)

    Sasaki, Shigekuni; Hasuda, Yoshinori; Ichino, Toshihiro

    1986-01-01

    Flexible thermal control materials are light weight, cheap and excellent in the practical applicability, and are expected to be applied to future long life, large capacity satellites. However, the flexible thermal control materials used at present have the defect that either the space environment withstanding capability or the thermal control performance is poor. Therefore, the authors examined the flexible thermal control materials which are excellent in both these properties, and have developed the thermal control material PEI-OSR using polyether imide films as the substrate. In this study, while comparing with the FEP Teflon with silver vapor deposition, which has been used so far for short life satellites, the long term reliability of the PEI-OSR supposing the use for seven years was examined. As the results, the FEP Teflon with silver vapor deposition caused cracking and separation by irradiation and heat cycle test, and became unusable, but the PEI-OSR did not change its flexibility at all. Also the thermal control performance of the PEI-OSR after the test equivalent to seven years was superior to the initial performance of the Kaptone with aluminum vapor deposition, which has excellent space environment endurance, thus it was clarified that the PEI-OSR is the most excellent for this purpose. (Kako, I.)

  4. A Comparative Study of Actuator Configurations for Satellite Attitude Control

    Directory of Open Access Journals (Sweden)

    Raymond Kristiansen

    2005-10-01

    Full Text Available In this paper a controllability study of different actuator configurations consisting of magnetic torquers, reaction wheels and a gravity boom is presented. The theoretical analysis is performed with use of controllability gramians, and simulation results with the different configurations are presented and compared regarding settling time and power consumption to substantiate the theoretical analysis. A reference model is also introduced to show how the power consumption can he lowered to the same magnitude as when magnetic torquers are used, without degrading the satellite response significantly.

  5. Sensor fault detection and recovery in satellite attitude control

    Science.gov (United States)

    Nasrolahi, Seiied Saeed; Abdollahi, Farzaneh

    2018-04-01

    This paper proposes an integrated sensor fault detection and recovery for the satellite attitude control system. By introducing a nonlinear observer, the healthy sensor measurements are provided. Considering attitude dynamics and kinematic, a novel observer is developed to detect the fault in angular rate as well as attitude sensors individually or simultaneously. There is no limit on type and configuration of attitude sensors. By designing a state feedback based control signal and Lyapunov stability criterion, the uniformly ultimately boundedness of tracking errors in the presence of sensor faults is guaranteed. Finally, simulation results are presented to illustrate the performance of the integrated scheme.

  6. Integrating of renewable energy in operation system: the Special Regime Control Centre (CECRE)

    International Nuclear Information System (INIS)

    Division, M.

    2007-01-01

    The implementation of Red Electrica de Espana Special Regime Control Centre (CECRE) has demonstrated the Spanish System Operators commitment of integrating the maximum possible wind power generation into the electrical system compatible with secure operation. With this leadership initiative,for the first time in the world, a System Operator Control Centre (CECRE) has succeeded in sending power control instructions to wind power generators over the country through Generation Control Centres (CGC) to which these generators must be connected complying with the Spanish Rules. (Author)

  7. Efficient medium access control protocol for geostationary satellite systems

    Institute of Scientific and Technical Information of China (English)

    王丽娜; 顾学迈

    2004-01-01

    This paper proposes an efficient medium access control (MAC) protocol based on multifrequency-time division multiple access (MF-TDMA) for geostationary satellite systems deploying multiple spot-beams and onboard processing,which uses a method of random reservation access with movable boundaries to dynamically request the transmission slots and can transmit different types of traffic. The simulation results have shown that our designed MAC protocol can achieve a high bandwidth utilization, while providing the required quality of service (QoS) for each class of service.

  8. A Distributed Flight Software Design for Satellite Formation Flying Control

    National Research Council Canada - National Science Library

    Mueller, Joseph B; Brito, Margarita

    2003-01-01

    .... Princeton Satellite Systems developed the Formation Flying Module (FFM) for TechSat 21 to provide autonomous reconfiguration, formation keeping,and collision avoidance capabilities to the three-satellite cluster...

  9. Passivity Based Nonlinear Attitude Control of the Rømer Satellite

    DEFF Research Database (Denmark)

    Quottrup, Michael Melholt; Krogh-Sørensen, J.; Wisniewski, Rafal

    2001-01-01

    This paper suggests nonlinear attitude control of the Danish satellite Rømer. This satellite will be designed to fulfil two scientific objectives: The observation of stellar oscillations and the detection and localisation of gamma-ray bursts. The satellite will be equipped with a tetrahedron...

  10. Design principles for CANDU control centres in response to evolving utility business needs

    International Nuclear Information System (INIS)

    Davey, E.

    2002-01-01

    Nuclear generation operators are facing a challenging business environment at the beginning of the new millennium. Evolving changes in business context, competitive commercial pressures, and changes in technology have dictated recurring evaluation of operational practices and the adequacy of supporting tools, and the pursuit of opportunities for operational improvement. A key area of utility operations that has been impacted by these changes is the nuclear plant control centre. Changes to workspace layout, equipment provisions, staffing, and work organization are examples of some of the adjustments being introduced to improve operational and safety effectiveness. This paper discusses some of the key factors influencing these changes and identifies additional design principles for CANDU control centres that will enable new control centre designs and retrofits of existing control centres to remain relevant and responsive to utility needs. (author)

  11. Retrospective exposure assessment and quality control in an international multi-centre case-control study

    DEFF Research Database (Denmark)

    Tinnerberg, H; Heikkilä, P; Huici-Montagud, A

    2003-01-01

    The paper presents the exposure assessment method and quality control procedure used in an international, multi-centre case-control study within a joint Nordic and Italian cohort. This study was conducted to evaluate whether occupational exposure to carcinogens influenced the predictivity of high...... was higher among the original assessors (the assessor from the same country as the subject) than the average prevalence assessed by the other four in the quality control round. The original assessors classified more job situations as exposed than the others. Several reasons for this are plausible: real...... country-specific differences, differences in information available to the home assessor and the others and misunderstandings or difficulties in translation of information. To ensure the consistency of exposure assessments in international retrospective case-control studies it is important to have a well...

  12. The role of function analysis in the ACR control centre design

    International Nuclear Information System (INIS)

    Leger, R.P.; Davey, E.C.

    2006-01-01

    An essential aspect of control centre design is the need to characterize: plant functions and their inter-relationships to support the achievement of operational goals, and roles for humans and automation in sharing and exchanging the execution of functions across all operational phases. Function analysis is a design activity that has been internationally accepted as an approach to satisfy this need. It is recognized as a fundamental and necessary component in the systematic approach to control centre design and is carried out early in the design process. A function analysis can provide a clear basis for: the control centre design for the purposes of design team communication, and customer or regulatory review, the control centre display and control systems, the staffing and layout requirements of the control centre, assessing the completeness of control centre displays and controls prior and supplementary to mock-up walkthroughs or simulator evaluations, and the design of operating procedures and training programs. This paper will explore the role for function analysis in supporting the design of the control centre. The development of the ACR control room will be used as an illustrative context for the discussion. The paper will also discuss the merits of using function analysis in a goal-or function-based approach resulting in a more robust, operationally compatible, and cost-effective design over the life of the plant. Two former papers have previously outlined, the evolution in AECL's application approach and lessons learned in applying function analysis in support of control room design. This paper provides the most recent update to this progression in application refinement. (author)

  13. H infinity controller design to a rigid-flexible satellite with two vibration modes

    International Nuclear Information System (INIS)

    De Souza, A G; De Souza, L C G

    2015-01-01

    The satellite attitude control system (ACS) design becomes more complex when the satellite structure has components like, flexible solar panels, antennas and mechanical manipulators. These flexible structures can interact with the satellite rigid parts during translational and/or rotational manoeuvre damaging the ACS pointing accuracy. Although, a well-designed controller can suppress such disturbances quickly, the controller error pointing may be limited by the minimum time necessary to suppress such disturbances thus affecting the satellite attitude acquisition. This paper deals with the rigid-flexible satellite ACS design using the H infinity method. The rigid-flexible satellite is represented by a beam connected to a central rigid hub at one end and free at the other one. The equations of motions are obtained considering small flexible deformations and the Euler-Bernoulli hypothesis. The results of the simulations have shown that the H-infinity controller was able to control the rigid motion and suppress the vibrations. (paper)

  14. Consensus of satellite cluster flight using an energy-matching optimal control method

    Science.gov (United States)

    Luo, Jianjun; Zhou, Liang; Zhang, Bo

    2017-11-01

    This paper presents an optimal control method for consensus of satellite cluster flight under a kind of energy matching condition. Firstly, the relation between energy matching and satellite periodically bounded relative motion is analyzed, and the satellite energy matching principle is applied to configure the initial conditions. Then, period-delayed errors are adopted as state variables to establish the period-delayed errors dynamics models of a single satellite and the cluster. Next a novel satellite cluster feedback control protocol with coupling gain is designed, so that the satellite cluster periodically bounded relative motion consensus problem (period-delayed errors state consensus problem) is transformed to the stability of a set of matrices with the same low dimension. Based on the consensus region theory in the research of multi-agent system consensus issues, the coupling gain can be obtained to satisfy the requirement of consensus region and decouple the satellite cluster information topology and the feedback control gain matrix, which can be determined by Linear quadratic regulator (LQR) optimal method. This method can realize the consensus of satellite cluster period-delayed errors, leading to the consistency of semi-major axes (SMA) and the energy-matching of satellite cluster. Then satellites can emerge the global coordinative cluster behavior. Finally the feasibility and effectiveness of the present energy-matching optimal consensus for satellite cluster flight is verified through numerical simulations.

  15. Observation and control of blinking nitrogen-vacancy centres in discrete nanodiamonds.

    Science.gov (United States)

    Bradac, C; Gaebel, T; Naidoo, N; Sellars, M J; Twamley, J; Brown, L J; Barnard, A S; Plakhotnik, T; Zvyagin, A V; Rabeau, J R

    2010-05-01

    Nitrogen-vacancy colour centres in diamond can undergo strong, spin-sensitive optical transitions under ambient conditions, which makes them attractive for applications in quantum optics, nanoscale magnetometry and biolabelling. Although nitrogen-vacancy centres have been observed in aggregated detonation nanodiamonds and milled nanodiamonds, they have not been observed in very small isolated nanodiamonds. Here, we report the first direct observation of nitrogen-vacancy centres in discrete 5-nm nanodiamonds at room temperature, including evidence for intermittency in the luminescence (blinking) from the nanodiamonds. We also show that it is possible to control this blinking by modifying the surface of the nanodiamonds.

  16. Zambia Tobacco Control Campaign | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The looming tobacco epidemic and its potential for thwarting development has prompted most governments in sub-Saharan Africa to ratify the World Health Organization's Framework Convention on Tobacco Control (WHO-FCTC). Ratifying countries must design and implement a national tobacco control action plan and ...

  17. A design basis for the development of advanced CANDU control centres

    International Nuclear Information System (INIS)

    Feher, M.P.; Davey, E.C.; Lupton, L.R.

    1995-01-01

    The basic design for current CANDU control centres was established in the early 1970's. Plants constructed since then have, for the most part, retained the same basic design. Several factors have led to the need to re-examine CANDU control centre design for plants to be built beyond the year 2000. These factors include the changing roles and responsibilities for the operations staff, an improved understanding of operational issues associated with supervisory control, an improved understanding of human error in operational situations, the opportunity for improved plant performance through the introduction of new technologies, and marketing pressures. This paper describes the proposed design bases for the development of advanced control centres to be implemented in CANDU plants beyond the year 2000. Four areas have been defined covering design goals, design principles, operational bases, and plant functional bases. (author)

  18. A design basis for the development of advanced CANDU control centres

    Energy Technology Data Exchange (ETDEWEB)

    Feher, M P; Davey, E C; Lupton, L R [Atomic Energy of Canada Ltd., Chalk River, ON (Canada)

    1996-12-31

    The basic design for current CANDU control centres was established in the early 1970`s. Plants constructed since then have, for the most part, retained the same basic design. Several factors have led to the need to re-examine CANDU control centre design for plants to be built beyond the year 2000. These factors include the changing roles and responsibilities for the operations staff, an improved understanding of operational issues associated with supervisory control, an improved understanding of human error in operational situations, the opportunity for improved plant performance through the introduction of new technologies, and marketing pressures. This paper describes the proposed design bases for the development of advanced control centres to be implemented in CANDU plants beyond the year 2000. Four areas have been defined covering design goals, design principles, operational bases, and plant functional bases. (author).

  19. Infection control for SARS in a tertiary neonatal centre.

    Science.gov (United States)

    Ng, P C; So, K W; Leung, T F; Cheng, F W T; Lyon, D J; Wong, W; Cheung, K L; Fung, K S C; Lee, C H; Li, A M; Hon, K L E; Li, C K; Fok, T F

    2003-09-01

    The Severe Acute Respiratory Syndrome (SARS) is a newly discovered infectious disease caused by a novel coronavirus, which can readily spread in the healthcare setting. A recent community outbreak in Hong Kong infected a significant number of pregnant women who subsequently required emergency caesarean section for deteriorating maternal condition and respiratory failure. As no neonatal clinician has any experience in looking after these high risk infants, stringent infection control measures for prevention of cross infection between patients and staff are important to safeguard the wellbeing of the work force and to avoid nosocomial spread of SARS within the neonatal unit. This article describes the infection control and patient triage policy of the neonatal unit at the Prince of Wales Hospital, Hong Kong. We hope this information is useful in helping other units to formulate their own infection control plans according to their own unit configuration and clinical needs.

  20. Tobacco Control Research Scholarships in Africa | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The funding will provide scholarships to master's students in schools of public health, economics, agriculture, environment, and other disciplines related to tobacco control ... Agent(e) responsable du CRDI ... Prevalence and predictors of cigarette smoking among adolescents of Ethiopia : school based cross sectional survey.

  1. Human factors engineering applied to Control Centre Design of a research nuclear reactor

    Energy Technology Data Exchange (ETDEWEB)

    Farias, Larissa P. de; Santos, Isaac J.A. Luquetti dos; Carvalho, Paulo V.R., E-mail: larissapfarias@ymail.com [Instituto de Engenharia Nuclear (DENN/SEESC/IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil). Lab, de Usabilidade e Confiabilidade Humana; Monteiro, Beany G. [Universidade Federal do Rio Janeiro (UFRJ), Rio Janeiro, RJ (Brazil). Departamento de Desenho Industrial

    2017-07-01

    The Human Factors Engineering (HFE) program is an essential aspect for the design of nuclear installations. The overall aim of the HFE program is the improvement of the operational reliability and safety of plant operation. The HFE program main purpose is to ensure that human factor practices are incorporated into the plant design, emphasizing man-machine interface issues and design improvement of the nuclear reactor Control Centre. The Control Centre of nuclear reactor is a combination of control rooms, control suites and local control stations, which are functionally connected and located on the reactor site. The objective of this paper is to present a design approach for the Control Centre of a nuclear reactor used to produce radioisotopes and for nuclear research, including human factor issues. The design approach is based on participatory design principles, using human factor standards, ergonomic guidelines, and the participation of a multidisciplinary team during all design phases. Using the information gathered, an initial sketch 3D of the Control Centre was developed. (author)

  2. Human factors engineering applied to Control Centre Design of a research nuclear reactor

    International Nuclear Information System (INIS)

    Farias, Larissa P. de; Santos, Isaac J.A. Luquetti dos; Carvalho, Paulo V.R.; Monteiro, Beany G.

    2017-01-01

    The Human Factors Engineering (HFE) program is an essential aspect for the design of nuclear installations. The overall aim of the HFE program is the improvement of the operational reliability and safety of plant operation. The HFE program main purpose is to ensure that human factor practices are incorporated into the plant design, emphasizing man-machine interface issues and design improvement of the nuclear reactor Control Centre. The Control Centre of nuclear reactor is a combination of control rooms, control suites and local control stations, which are functionally connected and located on the reactor site. The objective of this paper is to present a design approach for the Control Centre of a nuclear reactor used to produce radioisotopes and for nuclear research, including human factor issues. The design approach is based on participatory design principles, using human factor standards, ergonomic guidelines, and the participation of a multidisciplinary team during all design phases. Using the information gathered, an initial sketch 3D of the Control Centre was developed. (author)

  3. Enterprise Level Status and Control of Multi-Satellite Operations

    Data.gov (United States)

    National Aeronautics and Space Administration — Single-satellite mission operation centers are used for nearly all Goddard Space Flight Center (GSFC) mission ground data systems, with a focus on localized data...

  4. Miniature Reaction Wheel for Small Satellite Control, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall goal of this project is to design, develop, demonstrate, and deliver a miniature, high torque, low-vibration reaction wheel for use on small satellites....

  5. Development and control of a three-axis satellite simulator for the bifocal relay mirror initiative

    OpenAIRE

    Chernesky, Vincent S.

    2001-01-01

    The Three Axis Satellite Simulator (TASS) is a 4-foot diameter octagonal platform supported on a spherical air bearing. The platform hosts several satellite subsystems, including rate gyros, reaction wheels, thrusters, sun sensors, and an onboard control computer. This free-floating design allows for realistic emulation of satellite attitude dynamics in a laboratory environment. The bifocal relay mirror spacecraft system is composed of two optically coupled telescopes used to redirect the las...

  6. Attractive manifold-based adaptive solar attitude control of satellites in elliptic orbits

    Science.gov (United States)

    Lee, Keum W.; Singh, Sahjendra N.

    2011-01-01

    The paper presents a novel noncertainty-equivalent adaptive (NCEA) control system for the pitch attitude control of satellites in elliptic orbits using solar radiation pressure (SRP). The satellite is equipped with two identical solar flaps to produce control moments. The adaptive law is based on the attractive manifold design using filtered signals for synthesis, which is a modification of the immersion and invariance (I&I) method. The control system has a modular controller-estimator structure and has separate tunable gains. A special feature of this NCEA law is that the trajectories of the satellite converge to a manifold in an extended state space, and the adaptive law recovers the performance of a deterministic controller. This recovery of performance cannot be obtained with certainty-equivalent adaptive (CEA) laws. Simulation results are presented which show that the NCEA law accomplishes precise attitude control of the satellite in an elliptic orbit, despite large parameter uncertainties.

  7. An up-link power control for demand assignment International Business Satellite Communications Network

    Science.gov (United States)

    Nohara, Mitsuo; Takeuchi, Yoshio; Takahata, Fumio

    Up-link power control (UPC) is one of the essential technologies to provide efficient satellite communication systems operated at frequency bands above 10 GHz. A simple and cost-effective UPC scheme applicable to a demand assignment international business satellite communications system has been developed. This paper presents the UPC scheme, including the hardware implementation and its performance.

  8. Applying human factors to the design of control centre and workstation of a nuclear reactor

    International Nuclear Information System (INIS)

    Santos, Isaac J.A. Luquetti dos; Carvalho, Paulo V.R.; Goncalves, Gabriel de L.; Souza, Tamara D.M.F.; Falcao, Mariana A.

    2013-01-01

    Human factors is a body of scientific factors about human characteristics, covering biomedical, psychological and psychosocial considerations, including principles and applications in the personnel selection areas, training, job performance aid tools and human performance evaluation. Control Centre is a combination of control rooms, control suites and local control stations which are functionally related and all on the same site. Digital control room includes an arrangement of systems, equipment such as computers and communication terminals and workstations at which control and monitoring functions are conducted by operators. Inadequate integration between control room and operators reduces safety, increases the operation complexity, complicates operator training and increases the likelihood of human errors occurrence. The objective of this paper is to present a specific approach for the conceptual and basic design of the control centre and workstation of a nuclear reactor used to produce radioisotope. The approach is based on human factors standards, guidelines and the participation of a multidisciplinary team in the conceptual and basic phases of the design. Using the information gathered from standards and from the multidisciplinary team, an initial sketch 3D of the control centre and workstation are being developed. (author)

  9. Applying human factors to the design of control centre and workstation of a nuclear reactor

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Isaac J.A. Luquetti dos; Carvalho, Paulo V.R.; Goncalves, Gabriel de L., E-mail: luquetti@ien.gov.br [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Souza, Tamara D.M.F.; Falcao, Mariana A. [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ (Brazil). Dept. de Desenho Industrial

    2013-07-01

    Human factors is a body of scientific factors about human characteristics, covering biomedical, psychological and psychosocial considerations, including principles and applications in the personnel selection areas, training, job performance aid tools and human performance evaluation. Control Centre is a combination of control rooms, control suites and local control stations which are functionally related and all on the same site. Digital control room includes an arrangement of systems, equipment such as computers and communication terminals and workstations at which control and monitoring functions are conducted by operators. Inadequate integration between control room and operators reduces safety, increases the operation complexity, complicates operator training and increases the likelihood of human errors occurrence. The objective of this paper is to present a specific approach for the conceptual and basic design of the control centre and workstation of a nuclear reactor used to produce radioisotope. The approach is based on human factors standards, guidelines and the participation of a multidisciplinary team in the conceptual and basic phases of the design. Using the information gathered from standards and from the multidisciplinary team, an initial sketch 3D of the control centre and workstation are being developed. (author)

  10. Cognitive task load in a naval ship control centre : from identification to prediction

    NARCIS (Netherlands)

    Grootjen, M.; Neerincx, M.A.; Grootjen, M.; Veltman, J.

    2006-01-01

    Deployment of information and communication technology will lead to further automation of control centre tasks and an increasing amount of information to be processed. A method for establishing adequate levels of cognitive task load for the operators in such complex environments has been developed.

  11. Low sodium diet and pregnancy-induced hypertension: a multi-centre randomised controlled trial

    NARCIS (Netherlands)

    Knuist, M.; Bonsel, G. J.; Zondervan, H. A.; Treffers, P. E.

    1998-01-01

    To examine the effectiveness of the standard policy in the Netherlands to prescribe a sodium restricted diet to prevent or to treat mild pregnancy-induced hypertension. Multi-centre randomised controlled trial between April 1992 and April 1994. Seven practices of independent midwives and one

  12. Cities as command and control centres of the world economy: An empirical analysis, 2006–2015

    Directory of Open Access Journals (Sweden)

    Csomós György

    2017-12-01

    Full Text Available As a result of their rapid economic growth, several powerful corporate giants have emerged in developing countries, especially in China, operating not only in the traditional manufacturing sector, but also in high-tech industries and finance. Major cities in developing countries have gradually become important command and control centres of the global economy, and have also become powerful enough to be in the same tier as major cities of developed countries around the world. In this paper, I examine the position of cities as command and control centres on the basis of the power of their headquartered corporations. The result shows that until 2012, New York, London, Tokyo, and Paris; i.e. the global cities, were the leading command and control centres. However, the gap between these global cities and Beijing gradually closed, and by 2015, the Chinese capital outranked all the global cities. The outstanding performance of Beijing-based corporations that operate in financial, energy, and construction services sectors is the driving force behind Beijing’s increasing global power. In addition, the leading position of the global cities as command and control centres has been threatened by the San Francisco-San Jose metropolitan region, a newly emerging economic hub in the United States.

  13. A Survey of Congestion Control Techniques and Data Link Protocols in Satellite Networks

    OpenAIRE

    Fahmy, Sonia; Jain, Raj; Lu, Fang; Kalyanaraman, Shivkumar

    1998-01-01

    Satellite communication systems are the means of realizing a global broadband integrated services digital network. Due to the statistical nature of the integrated services traffic, the resulting rate fluctuations and burstiness render congestion control a complicated, yet indispensable function. The long propagation delay of the earth-satellite link further imposes severe demands and constraints on the congestion control schemes, as well as the media access control techniques and retransmissi...

  14. Testing command and control of the satellites in formation flight

    Science.gov (United States)

    Gheorghe, Popan; Gheorghe, Gh. Ion; Gabriel, Todoran

    2013-10-01

    The topics covered in the paper are mechatronic systems for determining the distance between the satellites and the design of the displacement system on air cushion table for satellites testing. INCDMTM has the capability to approach the collaboration within European Programms (ESA) of human exploration of outer space through mechatronic systems and accessories for telescopes, mechatronics systems used by the launchers, sensors and mechatronic systems for the robotic exploration programs of atmosphere and Mars. This research has a strong development component of industrial competitiveness many of the results of space research have direct applicability in industrial fabrication.

  15. Doping strategies to control A-centres in silicon: Insights from hybrid density functional theory

    KAUST Repository

    Wang, Hao; Chroneos, Alexander I.; Londos, Charalampos A.; Sgourou, Efstratia N.; Schwingenschlö gl, Udo

    2014-01-01

    Hybrid density functional theory is used to gain insights into the interaction of intrinsic vacancies (V) and oxygen-vacancy pairs (VO, known as A-centres) with the dopants (D) germanium (Ge), tin (Sn), and lead (Pb) in silicon (Si). We determine the structures as well as binding and formation energies of the DVO and DV complexes. The results are discussed in terms of the density of states and in view of the potential of isovalent doping to control A-centres in Si. We argue that doping with Sn is the most efficient isovalent doping strategy to suppress A-centres by the formation of SnVO complexes, as these are charge neutral and strongly bound. © 2014 the Owner Societies.

  16. A sit-ski design aimed at controlling centre of mass and inertia.

    Science.gov (United States)

    Langelier, Eve; Martel, Stéphane; Millot, Anne; Lessard, Jean-Luc; Smeesters, Cécile; Rancourt, Denis

    2013-01-01

    This article introduces a sit-ski developed for the Canadian Alpine Ski Team in view of the Vancouver 2010 Paralympic games. The design is predominantly based on controlling the mass distribution of the sit-ski, a critical factor in skiing performance and control. Both the antero-posterior location of the centre of mass and the sit-ski moment of inertia were addressed in our design. Our design provides means to adjust the antero-posterior centre of mass location of a sit-ski to compensate for masses that would tend to move the antero-posterior centre of mass location away from the midline of the binding area along the ski axis. The adjustment range provided is as large as 140 mm, thereby providing sufficient adaptability for most situations. The suspension mechanism selected is a four-bar linkage optimised to limit antero-posterior seat movement, due to suspension compression, to 7 mm maximum. This is about 5% of the maximum antero-posterior centre of mass control capacity (151 mm) of a human participant. Foot rest inclination was included in the design to modify the sit-ski inertia by as much as 11%. Together, these mass adjustment features were shown to drastically help athletes' skiing performance.

  17. Inventory Control System for a Healthcare Apparel Service Centre with Stockout Risk: A Case Analysis

    Directory of Open Access Journals (Sweden)

    An Pan

    2017-01-01

    Full Text Available Based on the real-world inventory control problem of a capacitated healthcare apparel service centre in Hong Kong which provides tailor-made apparel-making services for the elderly and disabled people, this paper studies a partial backordered continuous review inventory control problem in which the product demand follows a Poisson process with a constant lead time. The system is controlled by an (Q,r inventory policy which incorporate the stockout risk, storage capacity, and partial backlog. The healthcare apparel service centre, under the capacity constraint, aims to minimize the inventory cost and achieving a low stockout risk. To address this challenge, an optimization problem is constructed. A real case-based data analysis is conducted, and the result shows that the expected total cost on an order cycle is reduced substantially at around 20% with our proposed optimal inventory control policy. An extensive sensitivity analysis is conducted to generate additional insights.

  18. Inventory Control System for a Healthcare Apparel Service Centre with Stockout Risk: A Case Analysis.

    Science.gov (United States)

    Pan, An; Hui, Chi-Leung

    2017-01-01

    Based on the real-world inventory control problem of a capacitated healthcare apparel service centre in Hong Kong which provides tailor-made apparel-making services for the elderly and disabled people, this paper studies a partial backordered continuous review inventory control problem in which the product demand follows a Poisson process with a constant lead time. The system is controlled by an ( Q , r ) inventory policy which incorporate the stockout risk, storage capacity, and partial backlog. The healthcare apparel service centre, under the capacity constraint, aims to minimize the inventory cost and achieving a low stockout risk. To address this challenge, an optimization problem is constructed. A real case-based data analysis is conducted, and the result shows that the expected total cost on an order cycle is reduced substantially at around 20% with our proposed optimal inventory control policy. An extensive sensitivity analysis is conducted to generate additional insights.

  19. Magnetic dipole moment estimation and compensation for an accurate attitude control in nano-satellite missions

    Science.gov (United States)

    Inamori, Takaya; Sako, Nobutada; Nakasuka, Shinichi

    2011-06-01

    Nano-satellites provide space access to broader range of satellite developers and attract interests as an application of the space developments. These days several new nano-satellite missions are proposed with sophisticated objectives such as remote-sensing and observation of astronomical objects. In these advanced missions, some nano-satellites must meet strict attitude requirements for obtaining scientific data or images. For LEO nano-satellite, a magnetic attitude disturbance dominates over other environmental disturbances as a result of small moment of inertia, and this effect should be cancelled for a precise attitude control. This research focuses on how to cancel the magnetic disturbance in orbit. This paper presents a unique method to estimate and compensate the residual magnetic moment, which interacts with the geomagnetic field and causes the magnetic disturbance. An extended Kalman filter is used to estimate the magnetic disturbance. For more practical considerations of the magnetic disturbance compensation, this method has been examined in the PRISM (Pico-satellite for Remote-sensing and Innovative Space Missions). This method will be also used for a nano-astrometry satellite mission. This paper concludes that use of the magnetic disturbance estimation and compensation are useful for nano-satellites missions which require a high accurate attitude control.

  20. Manche centre

    International Nuclear Information System (INIS)

    1997-05-01

    After a general presentation of radioactivity and radioactive wastes and of the French national agency for the management of radioactive wastes (ANDRA), this brochure gives a general overview of the Manche low- and medium-level radioactive waste disposal centre: principles of storage safety, waste containers (first confinement barrier), storage facility and cover (second confinement barrier), the underground (third confinement barrier), the impact of the centre on its environment, and the control of radioactivity in the vicinity of the centre. (J.S.)

  1. An Operational Event Announcer for the LHC Control Centre Using Speech Synthesis

    CERN Document Server

    Page, S

    2011-01-01

    The LHC Island of the CERN Control Centre is a busy working environment with many status displays and running software applications. An audible event announcer was developed in order to provide a simple and efficient method to notify the operations team of events occurring within the many subsystems of the accelerator. The LHC Announcer uses speech synthesis to report messages based upon data received from multiple sources. General accelerator information such as injections, beam energies and beam dumps are derived from data received from the LHC Timing System. Additionally, a software interface is provided that allows other surveillance processes to send messages to the Announcer using the standard control system middleware. Events are divided into categories which the user can enable or disable depending upon their interest. Use of the LHC Announcer is not limited to the Control Centre and is intended to be available to a wide audience, both inside and outside CERN. To accommodate this, it...

  2. Reservation centre of Telecom I satellite French Telecommunication network offers a new service of switched digital circuit

    Science.gov (United States)

    Felix, J.

    The management center and new circuit switching services offered by the French Telecom I network are described. Attention is focused on business services. The satellite has a 125 Mbit/sec capability distributed over 5 frequency bands, yielding the equivalent of 1800 channels. Data are transmitted in digitized bursts with TDMA techniques. Besides the management center, Telecom I interfaces with 310 local network antennas with access managed by the center through a reservation service and protocol assignment. The center logs and supervises alarms and network events, monitors traffic, logs taxation charges and manages the man-machine dialog for TDMA and terrestrial operations. Time slots are arranged in terms of minimal 10 min segments. The reservations can be directly accessed by up to 1000 terminals. All traffic is handled on a call-by-call basis.

  3. Passivity based nonlinear attitude control of the Rømer satellite

    DEFF Research Database (Denmark)

    Quottrup, Michael Melholt; Krogh-Sørensen, J.; Wisniewski, Rafal

    This paper suggests nonlinear attitude control of the Danish satellite Rømer. This satellite will be designed to fulfil two scientific objectives: The observation of stellar oscillations and the detection and localisation of gamma-ray bursts. The satellite will be equipped with a tetrahedron...... configuration of Wide Angle Telescopes for Cosmic Hard x-rays (WATCH), that server the dual purpose of X-ray detectors and momentum wheels. By employing passivity theory it is shown, that the satellite is a passive system. This paper shows, that global asymptotic can be obtained with a passive and an imput...... and output strictly passive system in a feedback interconnection. It is demonstrated in a simulation study that the resultant control has a potential for on-board implementation in the acquistion phase, where global stabillity of the control law is vital...

  4. France. The Centre de la Manche disposal facility: Entering into the institutional control period

    International Nuclear Information System (INIS)

    2001-01-01

    The Centre de la Manche disposal facility, created by decree in 1969, is the first French near-surface radioactive waste disposal facility. It lies at the northwest end of the Cotentin peninsula, next to the COGEMA-La Hague fuel reprocessing plant. The Centre de la Manche facility occupies an area of about 150,000 m 2 . Its operation was terminated in late June 1994 with about 500,000 m 3 of packages disposed of. Operating feedback from the Centre de la Manche was used to design the second French disposal facility, located in the Aube, which has been receiving LILW since 1992. Since the end of the operating period, ANDRA has been preparing the statutory files to prepare the Centre de la Manche for its entry into the institutional control period. A new government decree will set the framework in which the Centre will evolve in this period. The regulatory process includes the filing of an application with the ministries concerned, containing a file with the requisite statutory documents, including an impact study of the facility on its environment as well as a hazard study. The file will then be submitted to a public inquiry, an essential informative period of the project designed to make a compilation of criticisms and suggestions from the public. In support of the application, a safety report has been sent to the Nuclear Installation Safety Directorate (DSIN) for a decision on the admissibility of the application. Recently, the Group of experts appointed by the DSIN which examined it has come out in favor of the creation of a new basic nuclear installation (i.e., a new government agency) for the institutional control period. A draft decree will then be submitted to the approval of the Interministerial Commission for Basic Nuclear Installations. This process, initiated in 1994, is nearing completion

  5. The CERN Control Centre Setting Standards for the 21st Century

    CERN Document Server

    Manglunki, Django

    2008-01-01

    In 2003, CERN decided to build a unified control centre to replace four of its control rooms: the â€ワMeyrin Control Room” which controlled the PS complex, the â€ワPrevessin Control Room” (PCR) which controlled the SPS and until 2000 LEP, the Technical Control Room (TCR), and the Cryogenics Control Room (QCR). After first contemplating a possible implementation next to the â€ワGlobe of Science and Innovation”, it was decided for budgetary reasons to build the new CERN Control Centre (CCC) on the same location as the PCR. This represented a 50% saving in construction costs as most of the technical infrastructure (computer network, water, electricity, ventilation) was already in place, but added stringent time constraints: civil engineering could not begin before the SPS shutdown in November 2004, yet the room had to be ready for the accelerator operations to resume in March 2006. Although this presented a strict construction schedule, it allowed the project to be completely driven by th...

  6. Learning from a mouse - how adoption of Disney methods could assist development of CANDU control centres

    Energy Technology Data Exchange (ETDEWEB)

    Davey, E. [Crew Systems Solutions, Deep River, Ontario (Canada)

    2005-07-01

    Many organizations are challenged with the tasks of identifying customer needs and expectations for their products, anticipating future product needs, communicating a future product vision to clients, and designing with today's technology to bring a future vision to successful realization. The design evolution of plant control centres is one aspect of CANDU development that faces such challenges. The Disney Corporation is an example of an organization that has been successful in consistently meeting these challenges for over fifty years; and some of the design practices proven in moviemaking, theme park and resort layout, and vacation experience organization may be helpful and effective when applied in other domains. This paper summarizes the findings from an examination of Disney Corporation design practices, and suggests how some practices could be used to simplify and enhance the design of future CANDU control centres. (author)

  7. Integrated control centre: Trading system for operation in a deregulated power market

    International Nuclear Information System (INIS)

    Nyland, S.; Reinertsen, T.; Gunnestad, J.; Botnan, G.O.

    1995-01-01

    The paper presents a trade system for operation in a deregulated power market. The trade system (ICC-Trade) is one of the application programs in the Integrated Control Centre (ICC). The Norwegian deregulated power market is briefly described in order to discuss the consequences of the new power market for the power utilities. The paper will also deal with the interconnection to other ICC application programs and how to make use of the communication with SCADA systems for support of managing market activities. Finally some future developments are presented. The trade system is developed in cooperation between a research institute, vendors of control centres, and power utilities, and is planned to be a commercial product during the spring of 1995. Before release the product will be tested in real life by a pilot customer. 4 figs

  8. Learning from a mouse - how adoption of Disney methods could assist development of CANDU control centres

    International Nuclear Information System (INIS)

    Davey, E.

    2005-01-01

    Many organizations are challenged with the tasks of identifying customer needs and expectations for their products, anticipating future product needs, communicating a future product vision to clients, and designing with today's technology to bring a future vision to successful realization. The design evolution of plant control centres is one aspect of CANDU development that faces such challenges. The Disney Corporation is an example of an organization that has been successful in consistently meeting these challenges for over fifty years; and some of the design practices proven in moviemaking, theme park and resort layout, and vacation experience organization may be helpful and effective when applied in other domains. This paper summarizes the findings from an examination of Disney Corporation design practices, and suggests how some practices could be used to simplify and enhance the design of future CANDU control centres. (author)

  9. Drag-Free Motion Control of Satellite for High-Precision Gravity Field Mapping

    DEFF Research Database (Denmark)

    Ziegler, Bent Lindvig; Blanke, Mogens

    2002-01-01

    High precision mapping of the geoid and the Earth's gravity field are of importance to a wide range of ongoing studies in areas like ocean circulation, solid Earth physics and ice sheet dynamics. Using a satellite in orbit around the Earth gives the opportunity to map the Earth's gravity field in 3...... will compromise measurement accuracy, unless they are accurately compensated by on-board thrusters. The paper concerns the design of a control system to performing such delicate drag compensation. A six degrees-of-freedom model for the satellite is developed with the model including dynamics of the satellite...

  10. Real time hardware-in-loop simulation of ESMO satellite attitude control system

    Directory of Open Access Journals (Sweden)

    Rune Finnset

    2006-04-01

    Full Text Available This paper studies attitude control of the ESMO satellite using six reaction thrusters. Bang-bang control with dead-zone and Pulse-Width Modulation (PWM for the modulation of the on-time of the thrusters are treated. Closed loop hardware-in-loop simulations, using themicrocontroller unit (MCU Microchip PIC18F452 for implementation of attitude control and MatLab in a standard PC for simulating satellite dynamics, are carried out. Results for real time simulation are compared with autonomous simulations. The controller gives a satisfactory performance in the real time environment.

  11. Secure, Autonomous, Intelligent Controller for Integrating Distributed Emergency Response Satellite Operations

    Science.gov (United States)

    Ivancic, William D.; Paulsen, Phillip E.; Miller, Eric M.; Sage, Steen P.

    2013-01-01

    This report describes a Secure, Autonomous, and Intelligent Controller for Integrating Distributed Emergency Response Satellite Operations. It includes a description of current improvements to existing Virtual Mission Operations Center technology being used by US Department of Defense and originally developed under NASA funding. The report also highlights a technology demonstration performed in partnership with the United States Geological Service for Earth Resources Observation and Science using DigitalGlobe(Registered TradeMark) satellites to obtain space-based sensor data.

  12. A task-based usage strategy for control centre wall displays

    International Nuclear Information System (INIS)

    Davey, E.

    2005-01-01

    This paper summarizes the findings from an exploratory definition of a usage strategy for multiple control centre wall displays in CANDU nuclear power plants. Wall displays are defined as large sized, vertically oriented display surfaces that may be positioned in various locations about a control room to support user information needs. The paper begins by discussing the need for a usage strategy for all control room information resources, and then reviews the history in wall display implementation and usage in nuclear power plant control rooms. The balance of the paper discusses the approach used in characterization and review of control room task information needs and definition of a wall display usage strategy. The paper concludes by outlining some of the possible impacts on future control room design and operations that the introduction of wall displays may imply. (author)

  13. Bodies or organisms? Medical encounter as a control apparatus at a primary care centre in Barcelona

    Directory of Open Access Journals (Sweden)

    Alejandro Zaballos Samper

    2013-07-01

    Full Text Available Medical practice is driven by technology, discourses, and knowledge about health and illness. This has resulted in its gaining a dominating position in power relations achieved by means of diagnosis, medicalization, and habit and conduct creation and maintenance. Interaction at primary care centres is built on mainstream biomedical views of both the medical discourse and the social practices related to health, illness and the human body. Moreover, it is also rooted on the ideologies conveyed by those social concepts, which in turn, permeate interaction all through with power relations. The present paper takes ethnographic data and in-depth interviews as a departing point to analyse how diagnosis, medicalization, and biopolicies for health prevention and improvement carried out in primary care centres in Barcelona make up a control apparatus. Furthermore, this essay also explores how the apparatus is developed in the medical encounter and turns the body into an organism.

  14. Linear Time Varying Approach to Satellite Attitude Control Using only Electromagnetic Actuation

    DEFF Research Database (Denmark)

    Wisniewski, Rafal

    2000-01-01

    , lightweight, and power efficient actuators is therefore crucial and viable. This paper discusser linear attitude control strategies for a low earth orbit satellite actuated by a set of mutually perpendicular electromagnetic coils. The principle is to use the interaction between the Earth's magnetic field......, nevertheless, a solution of the riccati equation gives an excellent frame for investigations provided in this paper. An observation that geomagnetic field changes approximately periodically when satellite is on a near polar orbit is used throughout this paper. Three types of attitude controllers are proposed......: an infinite horizon, a finite horizon, and a constant gain controller. Their performance is evaluated and compared in the simulation study of the environment...

  15. A Topology Control Strategy with Reliability Assurance for Satellite Cluster Networks in Earth Observation.

    Science.gov (United States)

    Chen, Qing; Zhang, Jinxiu; Hu, Ze

    2017-02-23

    This article investigates the dynamic topology control problemof satellite cluster networks (SCNs) in Earth observation (EO) missions by applying a novel metric of stability for inter-satellite links (ISLs). The properties of the periodicity and predictability of satellites' relative position are involved in the link cost metric which is to give a selection criterion for choosing the most reliable data routing paths. Also, a cooperative work model with reliability is proposed for the situation of emergency EO missions. Based on the link cost metric and the proposed reliability model, a reliability assurance topology control algorithm and its corresponding dynamic topology control (RAT) strategy are established to maximize the stability of data transmission in the SCNs. The SCNs scenario is tested through some numeric simulations of the topology stability of average topology lifetime and average packet loss rate. Simulation results show that the proposed reliable strategy applied in SCNs significantly improves the data transmission performance and prolongs the average topology lifetime.

  16. A Piecewise Affine Hybrid Systems Approach to Fault Tolerant Satellite Formation Control

    DEFF Research Database (Denmark)

    Grunnet, Jacob Deleuran; Larsen, Jesper Abildgaard; Bak, Thomas

    2008-01-01

    In this paper a procedure for modelling satellite formations   including failure dynamics as a piecewise-affine hybrid system is   shown. The formulation enables recently developed methods and tools   for control and analysis of piecewise-affine systems to be applied   leading to synthesis of fault...... tolerant controllers and analysis of   the system behaviour given possible faults.  The method is   illustrated using a simple example involving two satellites trying   to reach a specific formation despite of actuator faults occurring....

  17. Neural networks based three-axis satellite attitude control using only magnetic torquers

    International Nuclear Information System (INIS)

    Sivaprakash, N.; Shanmugam, J.; Natarajan, P.

    2005-01-01

    Full text: Magnetic control is a favorable way to stabilize small satellites. Often, the hardware is simple and lightweight, and does not degrade or change mass over time. However, a magnetic control system does have some disadvantages and limitations. The control, which is in the form of magnetic moment, can only be applied perpendicular to the local magnetic field. In addition, there is uncertainty in the Earth magnetic field models due to the complicated dynamic nature of the field. Also, the magnetic hardware and the spacecraft can interact, causing both to behave in undesirable ways. To overcome these limitations some intelligence is incorporated in the controller. In this paper, control laws are developed to stabilize spacecraft on Three axes. The motivation for this project is ANUSAT, which is a micro-satellite under development at Anna University in collaboration with ISRO. This control could be carried out solely with satellite's magnetometer measurements and its position in orbit. The magnetic dipole moment for control is: M = K p (B o - B r ) + K d (dB o /dt - dB r /dt) Where B o is the measured magnetic field, B r is the reference magnetic field, and K p and K d are the control position and rate gains respectively. The value of the controller gains are selected by the Intelligent Neural Network System in the feedback path. Control laws are numerically tested to show that the magnetic control system works within resolution limits

  18. Multi-technology control centre to integrate 460 MW renewables; Centro de control multitecnología para la integración de 460 MW renovables

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2016-07-01

    The new RWE Innogy Aersa Control Centre that has been certified to act as an interface with CECRE (the Renewable Energy Control Centre) since February 2015, connects RWE’s 20 renewable energy facilities with REE, the Spanish Electricity Grid. As a result, it ensures that wind farms, in addition to hydropower and solar plants, can inject the energy generated by its 460 MW installed safely and with no penalties. Green Eagle Solutions, a provider of software solutions for renewable energy companies, has collaborated with RWE in the development of this Control Centre, meeting the high standards of quality and safety required by RWE. This centre uses CompactSCADA® technology to integrate power generation facilities that need to be integrated in a Control Centre to communicate with REE’s CECRE. (Author)

  19. Cognitive task load in a naval ship control centre: from identification to prediction.

    Science.gov (United States)

    Grootjen, M; Neerincx, M A; Veltman, J A

    Deployment of information and communication technology will lead to further automation of control centre tasks and an increasing amount of information to be processed. A method for establishing adequate levels of cognitive task load for the operators in such complex environments has been developed. It is based on a model distinguishing three load factors: time occupied, task-set switching, and level of information processing. Application of the method resulted in eight scenarios for eight extremes of task load (i.e. low and high values for each load factor). These scenarios were performed by 13 teams in a high-fidelity control centre simulator of the Royal Netherlands Navy. The results show that the method provides good prediction of the task load that will actually appear in the simulator. The model allowed identification of under- and overload situations showing negative effects on operator performance corresponding to controlled experiments in a less realistic task environment. Tools proposed to keep the operator at an optimum task load are (adaptive) task allocation and interface support.

  20. An operational event announcer for the LHC control centre using speech synthesis

    International Nuclear Information System (INIS)

    Page, S.; Alemany Fernandez, R.

    2012-01-01

    The LHC Island of the CERN Control Centre is a busy working environment with many status displays and running software applications. An audible event announcer was developed in order to provide a simple and efficient method to notify the operations team of events occurring within the many subsystems of the accelerator. The LHC Announcer uses speech synthesis to report messages based upon data received from multiple sources. General accelerator information such as injections, beam energies and beam dumps are derived from data received from the LHC Timing System. Additionally, a software interface is provided that allows other surveillance processes to send messages to the Announcer using the standard control system middle-ware. Events are divided into categories which the user can enable or disable depending upon their interest. Use of the LHC Announcer is not limited to the Control Centre and is intended to be available to a wide audience, both inside and outside CERN. To accommodate this, it was designed to require no special software beyond a standard web browser. This paper describes the design of the LHC Announcer and how it is integrated into the LHC operational environment. (authors)

  1. Dual Fine Tracking Control of a Satellite Laser Communication Uplink

    National Research Council Canada - National Science Library

    Noble, Louis A

    2006-01-01

    A dual fine tracking control system (FTCS) is developed for a single aperture optical communication receiver to compensate for high frequency disturbances affecting tracking of two incident laser communication beams...

  2. Development of a Microelectromechanical System for Small Satellite Thermal Control

    National Research Council Canada - National Science Library

    Beasley, Matthew

    2004-01-01

    .... This new direction requires a similar evolution in thermal control. Previous techniques such as heat pipes and conventional radiators have large masses themselves and are not scaleable to fit these smaller designs...

  3. Implementation of EPICS based vacuum control system for variable energy cyclotron centre, Kolkata

    Science.gov (United States)

    Roy, Anindya; Bhole, R. B.; Nandy, Partha P.; Yadav, R. C.; Pal, Sarbajit; Roy, Amitava

    2015-03-01

    The vacuum system of the Room Temperature (K = 130) Cyclotron of Variable Energy Cyclotron Centre is comprised of vacuum systems of main machine and Beam Transport System. The vacuum control system is upgraded to a PLC based Automated system from the initial relay based Manual system. The supervisory control of the vacuum system is implemented in Experimental Physics and Industrial Control System (EPICS). An EPICS embedded ARM based vacuum gauge controller is developed to mitigate the requirement of vendor specific gauge controller for gauges and also for seamless integration of the gauge controllers with the control system. A set of MS-Windows ActiveX components with embedded EPICS Channel Access interface are developed to build operator interfaces with less complex programming and to incorporate typical Windows feature, e.g., user authentication, file handling, better fonts, colors, mouse actions etc. into the operator interfaces. The control parameters, monitoring parameters, and system interlocks of the system are archived in MySQL based EPICS MySQL Archiver developed indigenously. In this paper, we describe the architecture, the implementation details, and the performance of the system.

  4. Implementation of EPICS based vacuum control system for variable energy cyclotron centre, Kolkata

    Energy Technology Data Exchange (ETDEWEB)

    Roy, Anindya, E-mail: r-ani@vecc.gov.in; Bhole, R. B.; Nandy, Partha P.; Yadav, R. C.; Pal, Sarbajit; Roy, Amitava [Variable Energy Cyclotron Centre, 1/AF Bidhan Nagar, Kolkata 700064 (India)

    2015-03-15

    The vacuum system of the Room Temperature (K = 130) Cyclotron of Variable Energy Cyclotron Centre is comprised of vacuum systems of main machine and Beam Transport System. The vacuum control system is upgraded to a PLC based Automated system from the initial relay based Manual system. The supervisory control of the vacuum system is implemented in Experimental Physics and Industrial Control System (EPICS). An EPICS embedded ARM based vacuum gauge controller is developed to mitigate the requirement of vendor specific gauge controller for gauges and also for seamless integration of the gauge controllers with the control system. A set of MS-Windows ActiveX components with embedded EPICS Channel Access interface are developed to build operator interfaces with less complex programming and to incorporate typical Windows feature, e.g., user authentication, file handling, better fonts, colors, mouse actions etc. into the operator interfaces. The control parameters, monitoring parameters, and system interlocks of the system are archived in MySQL based EPICS MySQL Archiver developed indigenously. In this paper, we describe the architecture, the implementation details, and the performance of the system.

  5. Implementation of EPICS based vacuum control system for variable energy cyclotron centre, Kolkata

    International Nuclear Information System (INIS)

    Roy, Anindya; Bhole, R. B.; Nandy, Partha P.; Yadav, R. C.; Pal, Sarbajit; Roy, Amitava

    2015-01-01

    The vacuum system of the Room Temperature (K = 130) Cyclotron of Variable Energy Cyclotron Centre is comprised of vacuum systems of main machine and Beam Transport System. The vacuum control system is upgraded to a PLC based Automated system from the initial relay based Manual system. The supervisory control of the vacuum system is implemented in Experimental Physics and Industrial Control System (EPICS). An EPICS embedded ARM based vacuum gauge controller is developed to mitigate the requirement of vendor specific gauge controller for gauges and also for seamless integration of the gauge controllers with the control system. A set of MS-Windows ActiveX components with embedded EPICS Channel Access interface are developed to build operator interfaces with less complex programming and to incorporate typical Windows feature, e.g., user authentication, file handling, better fonts, colors, mouse actions etc. into the operator interfaces. The control parameters, monitoring parameters, and system interlocks of the system are archived in MySQL based EPICS MySQL Archiver developed indigenously. In this paper, we describe the architecture, the implementation details, and the performance of the system

  6. Automatic phase control in solar power satellite systems

    Science.gov (United States)

    Lindsey, W. C.; Kantak, A. V.

    1978-01-01

    Various approaches to the problem of generating, maintaining and distributing a coherent, reference phase signal over a large area are suggested, mathematically modeled and analyzed with respect to their ability to minimize: phase build-up, beam diffusion and beam steering phase jitter, cable length, and maximize power transfer efficiency. In addition, phase control configurations are suggested which alleviate the need for layout symmetry.

  7. Modal Control of a Satellite in Orbit about L3.

    Science.gov (United States)

    1980-12-01

    the right- half of the complex plane , are removed via the controller moving the unstable roots from the right- half to the left- half of the ...complex plane . Simultaneously, the other system roots remain in their original locations in the complex plane . Since the Poincare exponents of Hamiltonian... half - plane , the conjugate root in the left- half -

  8. Multiple Model Adaptive Attitude Control of LEO Satellite with Angular Velocity Constraints

    Science.gov (United States)

    Shahrooei, Abolfazl; Kazemi, Mohammad Hosein

    2018-04-01

    In this paper, the multiple model adaptive control is utilized to improve the transient response of attitude control system for a rigid spacecraft. An adaptive output feedback control law is proposed for attitude control under angular velocity constraints and its almost global asymptotic stability is proved. The multiple model adaptive control approach is employed to counteract large uncertainty in parameter space of the inertia matrix. The nonlinear dynamics of a low earth orbit satellite is simulated and the proposed control algorithm is implemented. The reported results show the effectiveness of the suggested scheme.

  9. Communication and Control in the Canadian North: The Role of Interactive Satellites.

    Science.gov (United States)

    Valaskakis, Gail G.

    In 1972 the Canadian government launched its first domestic communications satellite, Anik A, which relays direct broadcast television and telephone messages to northern communities. The impact of television on Inuit life has raised issues and concerns pertaining to native language broadcasting, media access and control, and cultural identity…

  10. Enantiopure Ferrocene-Based Planar-Chiral Iridacycles: Stereospecific Control of Iridium-Centred Chirality.

    Science.gov (United States)

    Arthurs, Ross A; Ismail, Muhammad; Prior, Christopher C; Oganesyan, Vasily S; Horton, Peter N; Coles, Simon J; Richards, Christopher J

    2016-02-24

    Reaction of [IrCp*Cl2 ]2 with ferrocenylimines (Fc=NAr, Ar=Ph, p-MeOC6 H4 ) results in ferrocene C-H activation and the diastereoselective synthesis of half-sandwich iridacycles of relative configuration Sp *,RIr *. Extension to (S)-2-ferrocenyl-4-(1-methylethyl)oxazoline gave highly diastereoselective control over the new elements of planar chirality and metal-based pseudo-tetrahedral chirality, to give both neutral and cationic half-sandwich iridacycles of absolute configuration Sc ,Sp ,RIr . Substitution reactions proceed with retention of configuration, with the planar chirality controlling the metal-centred chirality through an iron-iridium interaction in the coordinatively unsaturated cationic intermediate. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Guidance, Navigation, and Control Techniques and Technologies for Active Satellite Removal

    Science.gov (United States)

    Ortega Hernando, Guillermo; Erb, Sven; Cropp, Alexander; Voirin, Thomas; Dubois-Matra, Olivier; Rinalducci, Antonio; Visentin, Gianfranco; Innocenti, Luisa; Raposo, Ana

    2013-09-01

    This paper shows an internal feasibility analysis to de- orbit a non-functional satellite of big dimensions by the Technical Directorate of the European Space Agency ESA. The paper focuses specifically on the design of the techniques and technologies for the Guidance, Navigation, and Control (GNC) system of the spacecraft mission that will capture the satellite and ultimately will de-orbit it on a controlled re-entry.The paper explains the guidance strategies to launch, rendezvous, close-approach, and capture the target satellite. The guidance strategy uses chaser manoeuvres, hold points, and collision avoidance trajectories to ensure a safe capture. It also details the guidance profile to de-orbit it in a controlled re-entry.The paper continues with an analysis of the required sensing suite and the navigation algorithms to allow the homing, fly-around, and capture of the target satellite. The emphasis is placed around the design of a system to allow the rendezvous with an un-cooperative target, including the autonomous acquisition of both the orbital elements and the attitude of the target satellite.Analysing the capture phase, the paper provides a trade- off between two selected capture systems: the net and the tentacles. Both are studied from the point of view of the GNC system.The paper analyses as well the advanced algorithms proposed to control the final compound after the capture that will allow the controlled de-orbiting of the assembly in a safe place in the Earth.The paper ends proposing the continuation of this work with the extension to the analysis of the destruction process of the compound in consecutive segments starting from the entry gate to the rupture and break up.

  12. Tilted wheel satellite attitude control with air-bearing table experimental results

    Science.gov (United States)

    Inumoh, Lawrence O.; Forshaw, Jason L.; Horri, Nadjim M.

    2015-12-01

    Gyroscopic actuators for satellite control have attracted significant research interest over the years, but their viability for the control of small satellites has only recently started to become clear. Research on variable speed gyroscopic actuators has long been focused on single gimbal actuators; double gimbal actuators typically operate at constant wheel spin rate and allow tilt angle ranges far larger than the ranges needed to operate most satellite missions. This research examines a tilted wheel, a newly proposed type of inertial actuator that can generate torques in all three principal axes of a rigid satellite using a spinning wheel and a double tilt mechanism. The tilt mechanism tilts the angular momentum vector about two axes providing two degree of freedom control, while variation of the wheel speed provides the third. The equations of motion of the system lead to a singularity-free system during nominal operation avoiding the need for complex steering logic. This paper describes the hardware design of the tilted wheel and the experimental setup behind both standalone and spherical air-bearing tables used to test it. Experimental results from the air bearing table are provided with the results depicting the high performance capabilities of the proposed actuator in torque generation.

  13. Development of a hardware-in-loop attitude control simulator for a CubeSat satellite

    Science.gov (United States)

    Tapsawat, Wittawat; Sangpet, Teerawat; Kuntanapreeda, Suwat

    2018-01-01

    Attitude control is an important part in satellite on-orbit operation. It greatly affects the performance of satellites. Testing of an attitude determination and control subsystem (ADCS) is very challenging since it might require attitude dynamics and space environment in the orbit. This paper develops a low-cost hardware-in-loop (HIL) simulator for testing an ADCS of a CubeSat satellite. The simulator consists of a numerical simulation part, a hardware part, and a HIL interface hardware unit. The numerical simulation part includes orbital dynamics, attitude dynamics and Earth’s magnetic field. The hardware part is the real ADCS board of the satellite. The simulation part outputs satellite’s angular velocity and geomagnetic field information to the HIL interface hardware. Then, based on this information, the HIL interface hardware generates I2C signals mimicking the signals of the on-board rate-gyros and magnetometers and consequently outputs the signals to the ADCS board. The ADCS board reads the rate-gyro and magnetometer signals, calculates control signals, and drives the attitude actuators which are three magnetic torquers (MTQs). The responses of the MTQs sensed by a separated magnetometer are feedback to the numerical simulation part completing the HIL simulation loop. Experimental studies are conducted to demonstrate the feasibility and effectiveness of the simulator.

  14. Design of an Adaptive-Neural Network Attitude Controller of a Satellite using Reaction Wheels

    Directory of Open Access Journals (Sweden)

    Abbas Ajorkar

    2015-04-01

    Full Text Available In this paper, an adaptive attitude control algorithm is developed based on neural network for a satellite using four reaction wheels in a tetrahedron configuration. Then, an attitude control based on feedback linearization control has been designed and uncertainties in the moment of inertia matrix and disturbances torque have been considered. In order to eliminate the effect of these uncertainties, a multilayer neural network with back-propagation law is designed. In this structure, the parameters of the moment of inertia matrix and external disturbances are estimated and used in feedback linearization control law. Finally, the performance of the designed attitude controller is investigated by several simulations.

  15. Using the centre of percussion to design a steering controller for an autonomous race car

    Science.gov (United States)

    Kritayakirana, Krisada; Gerdes, J. Christian

    2012-01-01

    Understanding how a race car driver controls a vehicle at its friction limits can provide insights into the development of vehicle safety systems. In this paper, a race car driver's behaviour inspires the design of an autonomous racing controller. The resulting controller uses the vehicle's centre of percussion (COP) to design feedforward and feedback steering. At the COP, the effects of rotation and translation from the rear tire force cancel each other out; consequently, the feedforward steering command is robust to the disturbances from the rear tire force. Using the COP also simplifies the equations of motion, as the vehicle's lateral motion is decoupled from the vehicle's yaw motion and highlights the challenge of controlling a vehicle when the rear tires are highly saturated. The resulting dynamics can be controlled with a linear state feedback based on a lane-keeping system with additional yaw damping. Utilising Lyapunov theory, the closed-loop system is shown to remain stable even when the rear tires are highly saturated. The experimental results demonstrate that an autonomous vehicle can operate at its limits while maintaining a minimal lateral error.

  16. Research of remote control for Chinese Antarctica Telescope based on iridium satellite communication

    Science.gov (United States)

    Xu, Lingzhe; Yang, Shihai

    2010-07-01

    Astronomers are ever dreaming of sites with best seeing on the Earth surface for celestial observation, and the Antarctica is one of a few such sites only left owing to the global air pollution. However, Antarctica region is largely unaccessible for human being due to lacking of fundamental living conditions, travel facilities and effective ways of communication. Worst of all, the popular internet source as a general way of communication scarcely exists there. Facing such a dilemma and as a solution remote control and data transmission for telescopes through iridium satellite communication has been put forward for the Chinese network Antarctic Schmidt Telescopes 3 (AST3), which is currently under all round research and development. This paper presents iridium satellite-based remote control application adapted to telescope control. The pioneer work in China involves hardware and software configuration utilizing techniques for reliable and secure communication, which is outlined in the paper too.

  17. Linear Time Varying Approach to Satellite Attitude Control Using only Electromagnetic Actuation

    DEFF Research Database (Denmark)

    Wisniewski, Rafal

    1997-01-01

    , lightweight, and power efficient actuators is therefore crucial and viable. This paper discusses linear attitude control strategies for a low earth orbit satellite actuated by a set of mutually perpendicular electromagnetic coils. The principle is to use the interaction between the Earth's magnetic field...... systems is limited, nevertheless, a solution of the Riccati equation gives an excellent frame for investigations provided in this paper. An observation that geomagnetic field changes approximately periodically when a satellite is on a near polar orbit is used throughout this paper. Three types of attitude...... controllers are proposed: an infinite horizon, a finite horizon, and a constant gain controller. Their performance is evaluated and compared in the simulation study of the realistic environment....

  18. Measurement strategies for the Dutch Nuclear Emergency Response System of the National Poisons Control Centre

    International Nuclear Information System (INIS)

    Van Oostrum, I.E.A.; Joore, J.C.A.; Meulenbelt, J.; Savelkoul, T.J.F.

    1997-04-01

    The measurement strategy applicable to Public Health in case of a Nuclear Emergency affecting the Netherlands is presented. Within the framework of the Dutch Nuclear Emergency Response System (NPK, abbreviated in Dutch) the National Poisons Control Centre of the RIVM/AZU has an advisory obligation towards the Ministry of Public Health, Welfare and Sports (WVS). This role comprises advice to relevant ministries, coordination of the measurement strategies and advice on persons to be reviewed, i.e. physical, biological and clinical dosimetry. The choice of dosimetric methods and measurements to be achieved in case of a larger scale nuclear emergency in the Netherlands is discussed. An actual plan of handling is presented for this measurement plan. Intervention levels defined in NPK 1991 serve as guidelines for successive actions to be performed by regional health services. 8 figs., 6 tabs., 81 refs

  19. A satellite digital controller or 'play that PID tune again, Sam'. [Position, Integral, Derivative feedback control algorithm for design strategy

    Science.gov (United States)

    Seltzer, S. M.

    1976-01-01

    The problem discussed is to design a digital controller for a typical satellite. The controlled plant is considered to be a rigid body acting in a plane. The controller is assumed to be a digital computer which, when combined with the proposed control algorithm, can be represented as a sampled-data system. The objective is to present a design strategy and technique for selecting numerical values for the control gains (assuming position, integral, and derivative feedback) and the sample rate. The technique is based on the parameter plane method and requires that the system be amenable to z-transform analysis.

  20. 3-Axis magnetic control: flight results of the TANGO satellite in the PRISMA mission

    Science.gov (United States)

    Chasset, C.; Noteborn, R.; Bodin, P.; Larsson, R.; Jakobsson, B.

    2013-09-01

    PRISMA implements guidance, navigation and control strategies for advanced formation flying and rendezvous experiments. The project is funded by the Swedish National Space Board and run by OHB-Sweden in close cooperation with DLR, CNES and the Danish Technical University. The PRISMA test bed consists of a fully manoeuvrable MANGO satellite as well as a 3-axis controlled TANGO satellite without any Δ V capability. PRISMA was launched on the 15th of June 2010 on board DNEPR. The TANGO spacecraft is the reference satellite for the experiments performed by MANGO, either with a "cooperative" or "non-cooperative" behaviour. Small, light and low-cost were the keywords for the TANGO design. The attitude determination is based on Sun sensors and magnetometers, and the active attitude control uses magnetic torque rods only. In order to perform the attitude manoeuvres required to fulfil the mission objectives, using any additional gravity gradient boom to passively stabilize the spacecraft was not allowed. After a two-month commissioning phase, TANGO separated from MANGO on the 11th of August 2010. All operational modes have been successfully tested, and the pointing performance in flight is in accordance with expectations. The robust Sun Acquisition mode reduced the initial tip-off rate and placed TANGO into a safe attitude in MANGO. At the same time, it points its solar panel towards the Sun, and all payload equipments can be switched on without any restriction. This paper gives an overview of the TANGO Attitude Control System design. It then presents the flight results in the different operating modes. Finally, it highlights the key elements at the origin of the successful 3-axis magnetic control strategy on the TANGO satellite.

  1. Optimizing the Attitude Control of Small Satellite Constellations for Rapid Response Imaging

    Science.gov (United States)

    Nag, S.; Li, A.

    2016-12-01

    Distributed Space Missions (DSMs) such as formation flight and constellations, are being recognized as important solutions to increase measurement samples over space and time. Given the increasingly accurate attitude control systems emerging in the commercial market, small spacecraft now have the ability to slew and point within few minutes of notice. In spite of hardware development in CubeSats at the payload (e.g. NASA InVEST) and subsystems (e.g. Blue Canyon Technologies), software development for tradespace analysis in constellation design (e.g. Goddard's TAT-C), planning and scheduling development in single spacecraft (e.g. GEO-CAPE) and aerial flight path optimizations for UAVs (e.g. NASA Sensor Web), there is a gap in open-source, open-access software tools for planning and scheduling distributed satellite operations in terms of pointing and observing targets. This paper will demonstrate results from a tool being developed for scheduling pointing operations of narrow field-of-view (FOV) sensors over mission lifetime to maximize metrics such as global coverage and revisit statistics. Past research has shown the need for at least fourteen satellites to cover the Earth globally everyday using a LandSat-like sensor. Increasing the FOV three times reduces the need to four satellites, however adds image distortion and BRDF complexities to the observed reflectance. If narrow FOV sensors on a small satellite constellation were commanded using robust algorithms to slew their sensor dynamically, they would be able to coordinately cover the global landmass much faster without compensating for spatial resolution or BRDF effects. Our algorithm to optimize constellation satellite pointing is based on a dynamic programming approach under the constraints of orbital mechanics and existing attitude control systems for small satellites. As a case study for our algorithm, we minimize the time required to cover the 17000 Landsat images with maximum signal to noise ratio fall

  2. The mechanosensory calcium-selective ion channel: key component of a plasmalemmal control centre?

    Science.gov (United States)

    Pickard, B. G.; Ding, J. P.

    1993-01-01

    Mechanosensory calcium-selective ion channels probably serve to detect not only mechanical stress but also electrical, thermal, and diverse chemical stimuli. Because all stimuli result in a common output, most notably a shift in second messenger calcium concentration, the channels are presumed to serve as signal integrators. Further, insofar as second messenger calcium in turn gives rise to mechanical, electrical, and diverse chemical changes, the channels are postulated to initiate regulatory feedbacks. It is proposed that the channels and the feedback loops play a wide range of roles in regulating normal plant function, as well as in mediating disturbance of normal function by environmental stressors and various pathogens. In developing evidence for the physiological performance of the channel, a model for a cluster of regulatory plasmalemmal proteins and cytoskeletal elements grouped around a set of wall-to-membrane and transmembrane linkers has proved useful. An illustration of how the model might operate is presented. It is founded on the demonstration that several xenobiotics interfere both with normal channel behaviour and with gravitropic reception. Accordingly, the first part of the illustration deals with how the channels and the control system within which they putatively operate might initiate gravitropism. Assuming that gravitropism is an asymmetric expression of growth, the activities of the channels and the plasmalemmal control system are extrapolated to account for regulation of both rate and allometry of cell expansion. Finally, it is discussed how light, hormones, redox agents and herbicides could in principle affect growth via the putative plasmalemmal control cluster or centre.

  3. Control of effluents and environmental surveillance of the CEA centres. 1997 status; Controle des rejets et surveillance de l'environnement des centres CEA. Bilan 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-01

    The environmental quality in the vicinity of CEA facilities is a major concern of the safety policy of the CEA. The aim of this document is to inform the public about the gaseous and liquids radioactive effluents released by the CEA centres under the permission of the ministry. It provides a status of the effluents and of the radioactivity levels measured near the CEA centres in 1997, using air, water, vegetation and milk samples. A comparison is made with the measurements performed during the 1993-1996 period. The data presented comes from the regulatory registers transmitted to the agency for the protection against ionizing radiations (OPRI) which belongs to the ministry of health. (J.S.)

  4. Semi-active Attitude Control and Off-line Attitude Determination for the SEETI-Express Student Micro-satellite

    DEFF Research Database (Denmark)

    Alminde, Lars

    This paper concerns the development of the Attitude Determination and Control System (ADCS) for the SSETI-Express micro-satellite mission. The mission is an educational project involving 14 universities and the European Space Agency (ESA). The satellite has been designed and built, by students...

  5. Semi-active Attitude Control and Off-line Attitude Determination for the SSETI-Express Student Micro-satellite

    DEFF Research Database (Denmark)

    Alminde, Lars

    2005-01-01

    This paper concerns the development of the Attitude Determination and Control System (ADCS) for the SSETI-Express micro-satellite mission. The mission is an educational project involving 14 universities and the European Space Agency (ESA). The satellite has been designed and built, by students...

  6. A high precision dual feedback discrete control system designed for satellite trajectory simulator

    Science.gov (United States)

    Liu, Ximin; Liu, Liren; Sun, Jianfeng; Xu, Nan

    2005-08-01

    Cooperating with the free-space laser communication terminals, the satellite trajectory simulator is used to test the acquisition, pointing, tracking and communicating performances of the terminals. So the satellite trajectory simulator plays an important role in terminal ground test and verification. Using the double-prism, Sun etc in our group designed a satellite trajectory simulator. In this paper, a high precision dual feedback discrete control system designed for the simulator is given and a digital fabrication of the simulator is made correspondingly. In the dual feedback discrete control system, Proportional- Integral controller is used in velocity feedback loop and Proportional- Integral- Derivative controller is used in position feedback loop. In the controller design, simplex method is introduced and an improvement to the method is made. According to the transfer function of the control system in Z domain, the digital fabrication of the simulator is given when it is exposed to mechanism error and moment disturbance. Typically, when the mechanism error is 100urad, the residual standard error of pitching angle, azimuth angle, x-coordinate position and y-coordinate position are 0.49urad, 6.12urad, 4.56urad, 4.09urad respectively. When the moment disturbance is 0.1rad, the residual standard error of pitching angle, azimuth angle, x-coordinate position and y-coordinate position are 0.26urad, 0.22urad, 0.16urad, 0.15urad respectively. The digital fabrication results demonstrate that the dual feedback discrete control system designed for the simulator can achieve the anticipated high precision performance.

  7. Nanoscale magnetometry through quantum control of nitrogen–vacancy centres in rotationally diffusing nanodiamonds

    International Nuclear Information System (INIS)

    Maclaurin, D; Hall, L T; Martin, A M; Hollenberg, L C L

    2013-01-01

    The confluence of quantum physics and biology is driving a new generation of quantum-based sensing and imaging technology capable of harnessing the power of quantum effects to provide tools to understand the fundamental processes of life. One of the most promising systems in this area is the nitrogen–vacancy centre in diamond—a natural spin qubit which remarkably has all the right attributes for nanoscale sensing in ambient biological conditions. Typically the nitrogen–vacancy qubits are fixed in tightly controlled/isolated experimental conditions. In this work quantum control principles of nitrogen–vacancy magnetometry are developed for a randomly diffusing diamond nanocrystal. We find that the accumulation of geometric phases, due to the rotation of the nanodiamond plays a crucial role in the application of a diffusing nanodiamond as a bio-label and magnetometer. Specifically, we show that a freely diffusing nanodiamond can offer real-time information about local magnetic fields and its own rotational behaviour, beyond continuous optically detected magnetic resonance monitoring, in parallel with operation as a fluorescent biomarker. (paper)

  8. Falls prevention and balance rehabilitation in multiple sclerosis: a bi-centre randomised controlled trial.

    Science.gov (United States)

    Cattaneo, Davide; Rasova, Kamila; Gervasoni, Elisa; Dobrovodská, Gabriela; Montesano, Angelo; Jonsdottir, Johanna

    2018-03-01

    People with Multiple Sclerosis (PwMS) have a high incidence of accidental falls that have a potentially detrimental effect on their daily life participation. The effect of balance specific rehabilitation on clinical balance measures and frequency of falls in PwMS was studied. A bi-centre randomised rater-blinded controlled trial. Participants in both groups received 20 treatment sessions. Participants in the intervention group received treatment aimed at improving balance and mobility. Participants in the control group received treatments to reduce limitations at activity and body function level. Primary measures were frequency of fallers (>1 fall in two months) and responders (>3 points improvement) at the Berg Balance Scale (BBS). Data was analysed according to an intention to treat approach. One hundred and nineteen participants were randomised. Following treatment frequency of fallers was 22% in the intervention group and 23% in the control group, odds ratio (OR) and (confidence limits): 1.05 (0.41 to 2.77). Responders on the BBS were 28% in the intervention group and 33% in the control group, OR = 0.75 (0.30 to 1.91). At follow up ORs for fallers and responders at BBS were 0.98 (0.48 to 2.01) and 0.79 (0.26 to 2.42), respectively. Twenty sessions 2-3 times/week of balance specific rehabilitation did not reduce fall frequency nor improve balance suggesting the need for more frequent and challenging interventions. Implications for Rehabilitation Programs for balance rehabilitation can improve balance but their effects in fall prevention are unclear. Twenty treatments sessions 2/3 times per week did not reduced frequency of falls in MS. The comparison with similar studies suggests that higher intensity of practice of highly challenging balance activities appears to be critical to maximizing effectiveness.

  9. High Accuracy Attitude Control System Design for Satellite with Flexible Appendages

    Directory of Open Access Journals (Sweden)

    Wenya Zhou

    2014-01-01

    Full Text Available In order to realize the high accuracy attitude control of satellite with flexible appendages, attitude control system consisting of the controller and structural filter was designed. When the low order vibration frequency of flexible appendages is approximating the bandwidth of attitude control system, the vibration signal will enter the control system through measurement device to bring impact on the accuracy or even the stability. In order to reduce the impact of vibration of appendages on the attitude control system, the structural filter is designed in terms of rejecting the vibration of flexible appendages. Considering the potential problem of in-orbit frequency variation of the flexible appendages, the design method for the adaptive notch filter is proposed based on the in-orbit identification technology. Finally, the simulation results are given to demonstrate the feasibility and effectiveness of the proposed design techniques.

  10. A semi-physical simulation platform of attitude determination and control system for satellite

    Directory of Open Access Journals (Sweden)

    Yuanjin Yu

    2016-05-01

    Full Text Available A semi-physical simulation platform for attitude determination and control system is proposed to verify the attitude estimator and controller on ground. A simulation target, a host PC, many attitude sensors, and actuators compose the simulation platform. The simulation target is composed of a central processing unit board with VxWorks operating system and many input/output boards connected via Compact Peripheral Component Interconnect bus. The executable programs in target are automatically generated from the simulation models in Simulink based on Real-Time Workshop of MATLAB. A three-axes gyroscope, a three-axes magnetometer, a sun sensor, a star tracer, three flywheels, and a Global Positioning System receiver are connected to the simulation target, which formulates the attitude control cycle of a satellite. The simulation models of the attitude determination and control system are described in detail. Finally, the semi-physical simulation platform is used to demonstrate the availability and rationality of the control scheme of a micro-satellite. Comparing the results between the numerical simulation in Simulink and the semi-physical simulation, the semi-physical simulation platform is available and the control scheme successfully achieves three-axes stabilization.

  11. Predictors of employment for people with severe mental illness : results of an international six-centre randomised controlled trial

    NARCIS (Netherlands)

    Catty, Jocelyn; Lissouba, Pascale; White, Sarah; Becker, Thomas; Drake, Robert E.; Fioritti, Angelo; Knapp, Martin; Lauber, Christoph; Roessler, Wulf; Tomov, Toma; Van Busschbach, Jooske; Wiersma, Durk; Burns, Tom; Rossler, W.

    Background An international six-centre randomised controlled trial comparing individual placement and support (IPS) with usual vocational rehabilitation for people with serious mental illness found IPS to be more effective for all vocational outcomes. Aims To determine which patients with severe

  12. CMS Centre at CERN

    CERN Multimedia

    2007-01-01

    A new "CMS Centre" is being established on the CERN Meyrin site by the CMS collaboration. It will be a focal point for communications, where physicists will work together on data quality monitoring, detector calibration, offline analysis of physics events, and CMS computing operations. Construction of the CMS Centre begins in the historic Proton Synchrotron (PS) control room. The historic Proton Synchrotron (PS) control room, Opened by Niels Bohr in 1960, will be reused by CMS to built its control centre. TThe LHC@FNAL Centre, in operation at Fermilab in the US, will work very closely with the CMS Centre, as well as the CERN Control Centre. (Photo Fermilab)The historic Proton Synchrotron (PS) control room is about to start a new life. Opened by Niels Bohr in 1960, the room will be reused by CMS to built its control centre. When finished, it will resemble the CERN Contro...

  13. The WHO Collaborating Centre for Research and Control of Schistosomiasis at Niamey, Niger

    Directory of Open Access Journals (Sweden)

    Chippaux J-P

    1997-01-01

    Full Text Available The Centre de Recherche sur les Méningites et les Schistosomes (CERMES is a research institute depending on the Organisation de Coordination et de Coopération pour la lutte contre les Grandes Endémies - a West African Organization for Public Health - devoted to the studies on schistosomiasis and meningitis. The staff includes 32 persons with 11 scientists and one financial officer. The activities of the CERMES involving schistosomiasis concern three research units: (a ecology of human and animal schistosomiasis transmission; the CERMES defined the different patterns of schistosomiasis transmission in Niger (involving African dry savana; in this field, we have shown, (i the existence of important variability in conditions of transmission of S. haematobium and, (ii natural hybridization between parasitic species of the ruminants (S. bovis and S. curassoni and genetic interaction between human and animal parasites; (b definition of morbidity indicators usable for rapid assessment methods, for appraisal of the severity of the disease and for the evaluation of the efficiency of control methods; we have established the correlation between ultrasonographic data and some cheap and simple field indicators; (c immune response and protective immunity induced by recombinant glutathion S-transferase (Sm28, Sb28 and Sh28 in homologous and heterologous animal models including goats, sheep and non human primates (Erythrocebus patas. In Niger, we participate in all control programs against schistosomiasis to define control strategies, to supervise operations and to participate in their evaluation with external experts. International collaborations constitute a frame including four laboratories in Africa and six laboratories in developed countries (Europe and USA

  14. The Particle Physicists’ Song : the CERN Choir in full voice in the CERN Control Centre, with writer Danuta Orlowska

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    The song was submitted to CERN Courier by Danuta Orlowska, a clinical psychologist with Guy’s and St Thomas’ NHS Foundation Trust in London. It is written to be sung to the tune of The Hippopotamus Song, by Michael Flanders and Donald Swann, which will be well known to many British readers. On 3 February, members of the CERN choir gathered to give a rendition in the CERN Control Centre – the nerve centre of the LHC, which lies at the heart of the lyrics.

  15. Adaptive FTC based on Control Allocation and Fault Accommodation for Satellite Reaction Wheels

    DEFF Research Database (Denmark)

    Baldi, P.; Blanke, Mogens; Castaldi, P.

    2016-01-01

    and fault accommodation module directly exploiting the on-line fault estimates. The use of the nonlinear geometric approach and radial basis function neural networks allows to obtain a precise fault isolation, independently from the knowledge of aerodynamic disturbance parameters, and to design generalised......This paper proposes an active fault tolerant control scheme to cope with faults or failures affecting the flywheel spin rate sensors or satellite reaction wheel motors. The active fault tolerant control system consists of a fault detection and diagnosis module along with a control allocation...... estimation filters, which do not need a priori information about the internal model of the signal to be estimated. The adaptive control allocation and sensor fault accommodation can handle both temporal faults and failures. Simulation results illustrate the convincing fault correction and attitude control...

  16. Detumbling control for kinematically redundant space manipulator post-grasping a rotational satellite

    Science.gov (United States)

    Wang, Mingming; Luo, Jianjun; Yuan, Jianping; Walter, Ulrich

    2017-12-01

    The objective of this paper is to establish a detumbling strategy and a coordination control scheme for a kinematically redundant space manipulator post-grasping a rotational satellite. First, the dynamics of the kinematically redundant space robot after grasping the target is presented, which lays the foundation for the coordination controller design. Subsequently, optimal detumbling and motion planning strategy for the post-capture phase is proposed based on the quartic Bézier curves and adaptive differential evolution (DE) algorithm subject to the specific constraints. Both detumbling time and control torques are taken into account for the generation of the optimal detumbling strategy. Furthermore, a coordination control scheme is presented to track the designed reference path while regulating the attitude of the chaser to a desired value, which successfully dumps the initial angular velocity of the rotational satellite and controls the base attitude synchronously. Simulation results are presented for detumbling a target with rotational motion using a 7 degree-of-freedom (DOF) redundant space manipulator, which demonstrates the effectiveness of the proposed method.

  17. The state of lipid control in patients with diabetes in a public health care centre.

    Science.gov (United States)

    Wong, J S; Tan, F; Lee, P Y

    2007-01-01

    Achieving treatment targets has been difficult in treating diabetic patients. This cross-sectional study describes the lipid profiles of patients with diabetes mellitus at a public primary health care centre in Sarawak, Malaysia. The targets for lipid control were based on the International Diabetes Federation recommendation (2002). 1031 patients (98% Type 2 Diabetes) were studied. Fasting lipid profiles were available in 990 (96%) patients. The mean total cholesterol was 5.3 +/- 1.0 mmol/L, Triglycerides 1.90 +/- 1.26 mmol/L, HDL-C 1.28 +/- 0.33 mmol/L and LDL-C 3.2 +/- 0.9 mmol/L. Overall, 22% of patients achieved the treatment target for LDL-C level 1.1 mmol/L and 42% of patients had a target TG level below 1.5 mmol/L. Of the 40% of patients who received lipid-lowering drug, 17% achieved LDL-C target, 50% had LDL-C 2.6-4.4 mmol/ L and 33% have LDL-C > 4.0 mmol/L. For the remaining 60% not receiving any lipid lowering therapy, 68% had LDL-C between 2.6-4.0 mmol/L and 7% had LDL-C level > 4 mmol/L. Dyslipidemia is still under-treated despite the availability of effective pharmacological agents and the greatly increased risk of cardiovascular diseases in diabetic patients.

  18. Centre de la Manche institutional control period: after the first safety review - 59236

    International Nuclear Information System (INIS)

    Dutzer, Michel; Vervialle, Jean Pierre; Andre, Alain; Marchiol, Albert

    2012-01-01

    Centre de la Manche disposal facility is the first French surface disposal facility dedicated to low and intermediate level short lived radioactive waste. It started up in 1969. After a continuous improvement, in the design of disposal vaults, in operational modes, in the whole process of waste management, in the safety approach, the last packages were received in 1994. 527, 000 m 3 of waste packages have been disposed during the 25 years of operation. The facility was licensed for the institutional control period in 2003. The disposal vaults are covered with a multilayer capping system that includes a bituminous membrane to provide protection against rainwater infiltration. Water that might infiltrate through the membrane is collected by the bottom slab of the vaults to a pipe network implemented in an underground gallery. Measurements show an overall infiltration rate of about 3 l/m 2 /year that complies with the objective of Andra of a few liters per square meter and per year. Investigations are performed in order to assess the behavior of the membrane in the long term. For this purpose periodically samples of the bituminous membrane are taken and measurements are performed. As at the beginning of the operational period waste packages were not conditioned in accordance with the specifications that are presently prescribed to waste generators, some settlements can be observed on the ancient part or the facilities. At the end of 2009 some excavation works were performed in an area where a settlement of few tens of centimeters was observed. The integrity of the membrane could be observed and the adequacy of the selection of this option for the water-tightness of the capping system was so confirmed. Environmental monitoring includes radiological and chemical measurements for discharge, underground water and surface water. In the particular framework of Centre de la Manche, a contamination of groundwater by tritiated wastes occurred in 1976. Theses wastes were

  19. Centre of nuclear research experience in the control of personal exposition between 2002 - 2006

    International Nuclear Information System (INIS)

    Bayardo, Karina; Blanco, Daniel; Garcia, Fernando

    2008-01-01

    Full text: The control of the personal exposition in the public University is done by the Centre of Nuclear Research since 1999. A look at the last years permitted to note the increase in the Personal Dosimeter users. In this work we study the annual collective dose, the annual effective dose average and the different dose in each University area between 2002-2005. The annual effective dose limit for the Nuclear Regulatory Authority (Autoridad Reguladora Nuclear), are the suggested by the International Commission of Radiological Protection (ICRP). The actual application of the Basics Principles of Radiological Protection demand exposition levels as low as reasonable achievable (ALARA) considering economics and social factors. In this way we decrease the probability to induce illness in the expose personal and their descendants. The different dependences of the University where the service is given are: Faculty of Medicine (Radiology, Oncology, Clinical Oncology, Nuclear Medicine), Faculty of Chemistry (Radiochemistry), Faculty of Odontology (Radiology), Faculty of Veterinary (Radiology) and Faculty of Sciences (Centre of Nuclear Research). The number of users between 2002-2006 varied from 292 in year 2002 to 329 in the year 2006. We see a maximum of persons in the year 2004. The annual collective dose have been changing too, the lowest was 0.13 Sv.person in the year 2002 and the highest was 0.21 Sv.person in the year 2005. The annual collective dose permits the evaluation of the radiological impact of the radiation ionising manipulation in the University. In these 5 years the 96% of the annual effective dose average were under 4 mSv, and the 76% were smaller than the minimum detectable limit. This 76% were obtained in teach and researches areas. In the 4% higher than 4 mSv we can find areas where works with open radioactive sources like: Nuclear Medicine and Radiochemistry (Faulted de Pumice). In these places we detect annual effective doses of 15 mSv, these levels

  20. Conceptual design of a system for nuclear material control in a research centre according to the IAEA safeguards requirements

    International Nuclear Information System (INIS)

    Bueker, H.; Kotte, U.; Stein, G.

    1976-01-01

    In comparison with other facilities handling nuclear material, a nuclear research centre is characterized by a wider spectrum of operations. This requires a number of installations within the centre such as research reactors, critical assemblies, research institutes and central departments, operating, in general, independently of each other. Nuclear material is stored and processed in small quantities and in different chemical and physical configurations within prescribed license areas. The conceptual design of a new system for nuclear material control in a research centre has to consider the operator's and IAEA's safeguards requirements. Using the example of the Juelich Nuclear Research Centre in the Federal Republic of Germany, these requirements are being examined in conjunction with the specified peculiarities of a nuclear research centre. Following this, a division of the research centre into material balance areas and key measurement points is being proposed, based on the existing facilities and licence areas. The essential characteristic of the concept is a far-reaching displayability of the inventory and flow of nuclear material. The availability of information is based on differentiated material accountancy in conjunction with adequate measurement of nuclear material data. For data processing and generation of data, a computerized record and report system is to be provided as well as a central measurement system. The design of an integrated accountancy system with a central computer and remote terminals is described; various measuring appliances, now being developed or tested, for the non-destructive assay of nuclear material are specified. The functions of a central department for nuclear material management for operating these systems are discussed and the planned verification of nuclear material in the different material balance areas illustrated. On applying the measures described in this paper, the conceptual design of a system for nuclear material

  1. Command and Control Analysis of the South West Provincial Regional Emergency Operations Centre during Vancouver 2010

    Science.gov (United States)

    2011-06-01

    Venue Site WACC - Whistler Area Command Centre OTHER GPPAG - Government Partners Public Affairs Group 18 ANNEX B. Interview questions...Vancouver Vancouver Richmond WACC Decision Authority Link Information Sharing Link DOC’s 2010 Provincial Games Secretariat GPPAG CCG

  2. Fibromodulin: a master regulator of myostatin controlling progression of satellite cells through a myogenic program.

    Science.gov (United States)

    Lee, Eun Ju; Jan, Arif Tasleem; Baig, Mohammad Hassan; Ashraf, Jalaluddin Mohammad; Nahm, Sang-Soep; Kim, Yong-Woon; Park, So-Young; Choi, Inho

    2016-08-01

    Differentiation of muscle satellite cells (MSCs) involves interaction of the proteins present in the extracellular matrix (ECM) with MSCs to regulate their activity, and therefore phenotype. Herein, we report fibromodulin (FMOD), a member of the proteoglycan family participating in the assembly of ECM, as a novel regulator of myostatin (MSTN) during myoblast differentiation. In addition to having a pronounced effect on the expression of myogenic marker genes [myogenin (MYOG) and myosin light chain 2 (MYL2)], FMOD was found to maintain the transcriptional activity of MSTN Moreover, coimmunoprecipitation and in silico studies performed to investigate the interaction of FMOD helped confirm that it antagonizes MSTN function by distorting its folding and preventing its binding to activin receptor type IIB. Furthermore, in vivo studies revealed that FMOD plays an active role in healing by increasing satellite cell recruitment to sites of injury. Together, these findings disclose a hitherto unrecognized regulatory role for FMOD in MSCs and highlight new mechanisms whereby FMOD circumvents the inhibitory effects of MSTN and triggers myoblast differentiation. These findings offer a basis for the design of novel MSTN inhibitors that promote muscle regeneration after injury or for the development of pharmaceutical agents for the treatment of different muscle atrophies.-Lee, E. J., Jan, A. T., Baig, M. H., Ashraf, J. M., Nahm, S.-S., Kim, Y.-W., Park, S.-Y., Choi, I. Fibromodulin: a master regulator of myostatin controlling progression of satellite cells through a myogenic program. © FASEB.

  3. Nonlinear dynamics of mini-satellite respinup by weak internal controllable torques

    Energy Technology Data Exchange (ETDEWEB)

    Somov, Yevgeny, E-mail: e-somov@mail.ru [Samara State Technical University, Department for Guidance, Navigation and Control, 244 Molodogvardeyskaya Str., Samara 443100 (Russian Federation)

    2014-12-10

    Contemporary space engineering advanced new problem before theoretical mechanics and motion control theory: a spacecraft directed respinup by the weak restricted control internal forces. The paper presents some results on this problem, which is very actual for energy supply of information mini-satellites (for communication, geodesy, radio- and opto-electronic observation of the Earth et al.) with electro-reaction plasma thrusters and gyro moment cluster based on the reaction wheels or the control moment gyros. The solution achieved is based on the methods for synthesis of nonlinear robust control and on rigorous analytical proof for the required spacecraft rotation stability by Lyapunov function method. These results were verified by a computer simulation of strongly nonlinear oscillatory processes at respinuping of a flexible spacecraft.

  4. Nonlinear dynamics of mini-satellite respinup by weak internal controllable torques

    Science.gov (United States)

    Somov, Yevgeny

    2014-12-01

    Contemporary space engineering advanced new problem before theoretical mechanics and motion control theory: a spacecraft directed respinup by the weak restricted control internal forces. The paper presents some results on this problem, which is very actual for energy supply of information mini-satellites (for communication, geodesy, radio- and opto-electronic observation of the Earth et al.) with electro-reaction plasma thrusters and gyro moment cluster based on the reaction wheels or the control moment gyros. The solution achieved is based on the methods for synthesis of nonlinear robust control and on rigorous analytical proof for the required spacecraft rotation stability by Lyapunov function method. These results were verified by a computer simulation of strongly nonlinear oscillatory processes at respinuping of a flexible spacecraft.

  5. Phase Change Material for Temperature Control of Imager or Sounder on GOES Type Satellites in GEO

    Science.gov (United States)

    Choi, Michael K.

    2014-01-01

    This paper uses phase change material (PCM) in the scan cavity of an imager or sounder on satellites in geostationary orbit (GEO) to maintain the telescope temperature stable. When sunlight enters the scan aperture, solar heating causes the PCM to melt. When sunlight stops entering the scan aperture, the PCM releases the thermal energy stored to keep the components in the telescope warm. It has no moving parts or bimetallic springs. It reduces heater power required to make up the heat lost by radiation to space through the aperture. It is an attractive thermal control option to a radiator with a louver and a sunshade.

  6. Flight results from the gravity-gradient-controlled RAE-1 satellite

    Science.gov (United States)

    Blanchard, D. L.

    1986-01-01

    The in-orbit dynamics of a large, flexible spacecraft has been modeled with a computer simulation, which was used for designing the control system, developing a deployment and gravity-gradient capture procedure, predicting the steady-state behavior, and designing a series of dynamics experiments for the Radio Astronomy Explorer (RAE) satellite. This flexible body dynamics simulator permits three-dimensional, large-angle rotation of the total spacecraft and includes effects of orbit eccentricity, thermal bending, solar pressure, gravitational accelerations, and the damper system. Flight results are consistent with the simulator predictions and are presented for the deployment and capture phases, the steady-state mission, and the dynamics experiments.

  7. Development of a green bipropellant hydrogen peroxide thruster for attitude control on satellites

    Science.gov (United States)

    Woschnak, A.; Krejci, D.; Schiebl, M.; Scharlemann, C.

    2013-03-01

    This document describes the selection assessment of propellants for a 1-newton green bipropellant thruster for attitude control on satellites. The development of this thruster was conducted as a part of the project GRASP (Green Advanced Space Propellants) within the European FP7 research program. The green propellant combinations hydrogen peroxide (highly concentrated with 87.5 %(wt.)) with kerosene or hydrogen peroxide (87.5 %(wt.)) with ethanol were identified as interesting candidates and were investigated in detail with the help of an experimental combustion chamber in the chemical propulsion laboratory at the Forschungsund Technologietransfer GmbH ― Fotec. Based on the test results, a final selection of propellants was performed.

  8. Pipeline Analyzer using the Fractional Fourier Transform for Engine Control and Satellites Data

    Directory of Open Access Journals (Sweden)

    Darian M. Onchiș

    2011-09-01

    Full Text Available The aim of this paper is to present an algorithm for computing the fractional Fourier transform integrated into the pipeline of processing multi-variate and distributed data recorded by the engine control unit (ECU of a car and its satellites. The role of this transform is vital in establishing a time-variant filter and therefore it must be computed in a fast way. But for large scale time series, the application of the discrete fractional Fourier transform involves the computations of a large number of Hermite polynomials of increasingly order. The parallel algorithm presented will optimally compute the discrete Fourier-type transform for any given angle.

  9. A Topology Control Strategy with Reliability Assurance for Satellite Cluster Networks in Earth Observation

    Directory of Open Access Journals (Sweden)

    Qing Chen

    2017-02-01

    Full Text Available This article investigates the dynamic topology control problemof satellite cluster networks (SCNs in Earth observation (EO missions by applying a novel metric of stability for inter-satellite links (ISLs. The properties of the periodicity and predictability of satellites’ relative position are involved in the link cost metric which is to give a selection criterion for choosing the most reliable data routing paths. Also, a cooperative work model with reliability is proposed for the situation of emergency EO missions. Based on the link cost metric and the proposed reliability model, a reliability assurance topology control algorithm and its corresponding dynamic topology control (RAT strategy are established to maximize the stability of data transmission in the SCNs. The SCNs scenario is tested through some numeric simulations of the topology stability of average topology lifetime and average packet loss rate. Simulation results show that the proposed reliable strategy applied in SCNs significantly improves the data transmission performance and prolongs the average topology lifetime.

  10. Design of tracking mount and controller for mobile satellite laser ranging system

    Science.gov (United States)

    Park, Cheol Hoon; Son, Young Su; Kim, Byung In; Ham, Sang Young; Lee, Sung Whee; Lim, Hyung Chul

    2012-01-01

    In this study, we have proposed and implemented a design for the tracking mount and controller of the ARGO-M (Accurate Ranging system for Geodetic Observation - Mobile) which is a mobile satellite laser ranging (SLR) system developed by the Korea Astronomy and Space Science Institute (KASI) and Korea Institute of Machinery and Materials (KIMM). The tracking mount comprises a few core components such as bearings, driving motors and encoders. These components were selected as per the technical specifications for the tracking mount of the ARGO-M. A three-dimensional model of the tracking mount was designed. The frequency analysis of the model predicted that the first natural frequency of the designed tracking mount was high enough. The tracking controller is simulated using MATLAB/xPC Target to achieve the required pointing and tracking accuracy. In order to evaluate the system repeatability and tracking accuracy of the tracking mount, a prototype of the ARGO-M was fabricated, and repeatability tests were carried out using a laser interferometer. Tracking tests were conducted using the trajectories of low earth orbit (LEO) and high earth orbit (HEO) satellites. Based on the test results, it was confirmed that the prototype of the tracking mount and controller of the ARGO-M could achieve the required repeatability along with a tracking accuracy of less than 1 arcsec.

  11. Tether dynamics and control results for tethered satellite system's initial flight

    Science.gov (United States)

    Chapel, Jim D.; Flanders, Howard

    The recent Tethered Satellite System-1 (TSS-1) mission has provided a wealth of data concerning the dynamics of tethered systems in space and has demonstrated the effectiveness of operational techniques designed to control these dynamics. In this paper, we review control techniques developed for managing tether dynamics, and discuss the results of using these techniques for the Tethered Satellite System's maiden flight on STS-46. In particular, the flight results of controlling libration dynamics, string dynamics, and slack tether are presented. These results show that tether dynamics can be safely managed. The overall stability of the system was found to be surprisingly good even at relatively short tether lengths. In fact, the system operated in passive mode at a tether length of 256 meters for over 9 hours. Only monitoring of the system was required during this time. Although flight anomalies prevented the planned deployment to 20 km, the extended operations at shorter tether lengths have proven the viability of using tethers in space. These results should prove invaluable in preparing for future missions with tethered objects in space.

  12. The manned space-laboratories control centre - MSCC. Operational functions and its implementation

    Science.gov (United States)

    Brogl, H.; Kehr, J.; Wlaka, M.

    This paper describes the functions of the MSCC during the operations of the Columbus Attached Laboratory and the Free Flying Laboratory as part of the In-Orbit-Infrastructure Ground Segment. For the Attached Laboratory, MSCC payload operations coordination for European experiments within the Attached Laboratory and elsewhere on the Space Station Freedom will be explained. The Free Flying Laboratory will be operated and maintained exclusively from the MSCC during its 30 years lifetime. Several operational scenarios will demonstrate the role of the MSCC during routine - and servicing operations: of main importance are the servicing activities of the Attached Laboratory and the Free Flyer at the Space Station as well as servicing of the Free Flyer by the European Space Plane Hermes. The MSCC will have complex operational-, communications-and management interfaces with the IOI Ground Segment, the Space Station User community and with the international partners. Columbus User Support Centres will be established in many European member states, which have to be coordinated by the MSCC to ensure the proper reception of the scientific data and to provide them with quick access to their experiments in space. For operations planning and execution of experiments in the Attached Laboratory, a close cooperation with the Space Station control authorities in the USA will be established. The paper will show the development of the MSCC being initially used for the upcoming Spacelab Mission D-2 (MSCC Phase-1) and later upgraded to a Columbus dedicated control centre (MSCC Phase-2). For the initial construction phase the establishing of MSCC requirements, the philosophie used for the definition of the 'basic infrastructure' and key features of the installed facilities will be addressed. Resulting from Columbus and D-2 requirements, the sizing of the building with respect to controlrooms, conference rooms, office spare and simulation high-bay areas will be discussed. The defined 'basic

  13. Scientists of Russian Federal Nuclear Centre - ARSRITP and arms control and nuclear weapons non-proliferation problems

    International Nuclear Information System (INIS)

    Avrorin, E.N.; Andrusenko, B.A.; Voznyuk, R.I.; Voloshin, N.P.

    1994-01-01

    The activity of scientists of Russian Federal Nuclear Centre (RFNC) -ARSRITP in the field of nuclear disarmament control for the period of 1974 -1993 is discussed. RFNC - ARSRITP scientists in collaboration with american specialists have developed and employed in practice the techniques and equipment to control the bilateral Treaty on the limitation of Nuclear -Weapon Test. Experience of control over nuclear tests of threshold power and realization of new RFNC - ARSRITP scientific and technical projects have made a basis for development of measures and means of possible control methods to observe complete nuclear test ban

  14. [Internal quality control of the blood products in the Lomé National Blood Transfusion Centre].

    Science.gov (United States)

    Fétéké, L; Mawussi, K; Lakté, P; Kuéviakoe, I M; Haudrechy, D; Ségbéna, A Y

    2008-07-01

    Evaluate the conformity of blood red cells units prepared in the Lomé CNTS with European norms concerning volume, haemoglobin content and haematocrite. Measure the conservation of the haemostatic properties and the rate of haemostasis factors V and VIII in the fresh frozen plasma. Measure the rate of residual cells in the plasma. In the year 2006, from March 1st to April 15th, we analysed the quality of 135 units of whole blood, red blood cells (RBC) and plasma from blood donors in the Lomé National Blood Transfusion Centre. The quality control had concerned: the volume of whole blood units; the volume, the haemoglobin content and the haematocrite of red blood cells units; the volume, the prothrombin rate, the cephalin with activator time (TCA), the rate of haemostasis factors V and VIII and the number of residual cells (red cells, leucocytes and platelets) in the plasma. Among the 135 units of whole blood which were controlled, 50.57% were in conformity with the norms concerning the volume. The red blood cells units were in conformity with norms concerning their volume, their haemoglobin content and their haematocrite respectively in 21.48%, 80.75% and 20% of the cases. The volume of 75.56% of the plasma units controlled were conform with the norm. All of the plasma units were conform with the norm concerning the number of residual platelets while the number of residual red blood cells and leucocytes were conform respectively in 80.74% and 60%. The percentage of conformity concerning the prothrombin rate, the TCA, the coagulation factor V and the factor VIII were respectively 66.67; 97.78; 48.89 and 47.4 before freezing, and 54.81; 88.14; 64.44; 84.44 a month after freezing. To improve the quality of the new blood products of the Lomé CNTS, some correctives actions must be applied concerning the adequate volume of blood which must be collected from the donors, the position of the blood bags in during the centrifugation and the volume of plasma which must be

  15. Risk factors for prostate cancer in Universiti Kebangsaan Malaysia Medical Centre: a case-control study.

    Science.gov (United States)

    Subahir, Mohd Nizam; Shah, Shamsul Azhar; Zainuddin, Zulkifli Md

    2009-01-01

    In Malaysia, prostate cancer is ranked 6th among male cancer and expected to increase in the future. Several factors have shown to be related to prostate cancer such as sociodemographic, lifestyle, diet, occupational exposure, medical and health status. This is the first time a similar study was conducted in Malaysia to recognize the risk factors for prostate cancer patients who came for treatment at University Kebangsaan Malaysia Medical Centre (UKMMC). Prostate cancer cases diagnosed between 2003 and 2008 which met with the inclusion criteria were included in the study. One hundred and twelfth (112) pairs of cases and controls matched by age and ethnicity were analysed. McNemar Odds Ratios (OR(M)) were calculated using McNemar Calculator software for univariate analysis while conditional logistic regression was used for multivariate analysis, both using SPSS version 12.0. Most of the prostate cancer patients (68.8%) that came for treatment in UKMMC were above 70 years old. The majority were Chinese (50.0%) followed by Malay (46.4%) and Indian (3.6%). Multivariate analysis showed cases were more likely to have a first-degree relative with a history of cancer (OR= 3.77, 95% CI= 1.19-11.85), to have been exposed to pesticides (OR= 5.57, 95% CI= 1.75-17.78) and consumed more meat (OR= 12.23, 95% CI= 3.89-39.01). Significantly reduced risks of prostate cancer were noted among those consuming more vegetables (OR= 0.12, 95% CI= 0.02-0.84), more tomatoes (OR= 0.35, 95% CI= 0.13-0.93) and those who had frequent sexual intercourse (OR= 0.44, 95% CI= 0.19-0.96). Some lifestyle and occupation factors are strong predictors of the occurrence of prostate cancer among patients in UKMMC. More importantly, with the identification of the potentially modifiable risk factors, proper public health intervention can be improved.

  16. Evolutionary design of a satellite thermal control system: Real experiments for a CubeSat mission

    International Nuclear Information System (INIS)

    Escobar, Emanuel; Diaz, Marcos; Zagal, Juan Cristóbal

    2016-01-01

    Highlights: • GAs applied to automate design of CubeSat passive thermal control system (coating). • Simulation adapted with real physical data (mockup experiment in vacuum chamber). • Obtained coating patterns consistently outperform engineered solutions (by 5 K). • Evolved coating patterns are far superior (by 8 K) than unpainted aluminum. - Abstract: This paper studies the use of artificial evolution to automate the design of a satellite passive thermal control system. This type of adaptation often requires the use of computer simulations to evaluate fitness of a large number of candidate solutions. Simulations are required to be expedient and accurate so that solutions can be successfully transferred to reality. We explore a design process that involves three steps. On a first step candidate solutions (implemented as surface paint tiling patterns) are tested using a FEM model and ranked according to their quality to meet mission temperature requirements. On a second step the best individual is implemented as a real physical satellite mockup and tested inside a vacuum chamber, having light sources imitating the effect of solar light. On a third step the simulation model is adapted with data obtained during the real evaluation. These updated models can be further employed for continuing genetic search. Current differences between our simulation and our real physical setup are in the order of 1.45 K mean squared error for faces pointing toward the light source and 2.4 K mean squared errors for shadowed faces. We found that evolved tiling patterns can be 5 K below engineered patterns and 8 K below using unpainted aluminum satellite surfaces.

  17. Evaluating implementation of a fire-prevention injury prevention briefing in children's centres: Cluster randomised controlled trial.

    Directory of Open Access Journals (Sweden)

    Toity Deave

    Full Text Available Many developed countries have high mortality rates for fire-related deaths in children aged 0-14 years with steep social gradients. Evidence-based interventions to promote fire safety practices exist, but the impact of implementing a range of these interventions in children's services has not been assessed. We developed an Injury Prevention Briefing (IPB, which brought together evidence about effective fire safety interventions and good practice in delivering interventions; plus training and facilitation to support its use and evaluated its implementation.We conducted a cluster randomised controlled trial, with integrated qualitative and cost-effectiveness nested studies, across four study sites in England involving children's centres in disadvantaged areas; participants were staff and families attending those centres. Centres were stratified by study site and randomised within strata to one of three arms: IPB plus facilitation (IPB+, IPB only, usual care. IPB+ centres received initial training and facilitation at months 1, 3, and 8. Baseline data from children's centres were collected between August 2011 and January 2012 and follow-up data were collected between June 2012 and June 2013. Parent baseline data were collected between January 2012 and May 2012 and follow-up data between May 2013 and September 2013. Data comprised baseline and 12 month parent- and staff-completed questionnaires, facilitation contact data, activity logs and staff interviews. The primary outcome was whether families had a plan for escaping from a house fire. Treatment arms were compared using multilevel models to account for clustering by children's centre.1112 parents at 36 children's centres participated. There was no significant effect of the intervention on families' possession of plans for escaping from a house fire (adjusted odds ratio (AOR IPB only vs. usual care: 0.93, 95%CI 0.58, 1.49; AOR IPB+ vs. usual care 1.41, 95%CI 0.91, 2.20. However, significantly more

  18. Evaluation of efficacy of a new hybrid fusion device: a randomized, two-centre controlled trial.

    Science.gov (United States)

    Siewe, Jan; Bredow, Jan; Oppermann, Johannes; Koy, Timmo; Delank, Stefan; Knoell, Peter; Eysel, Peer; Sobottke, Rolf; Zarghooni, Kourosh; Röllinghoff, Marc

    2014-09-05

    The 360° fusion of lumbar segments is a common and well-researched therapy to treat various diseases of the spine. But it changes the biomechanics of the spine and may cause adjacent segment disease (ASD). Among the many techniques developed to avoid this complication, one appears promising. It combines a rigid fusion with a flexible pedicle screw system (hybrid instrumentation, "topping off"). However, its clinical significance is still uncertain due to the lack of conclusive data. The study is a randomized, therapy-controlled, two-centre trial conducted in a clinical setting at two university hospitals. If they meet the criteria, outpatients presenting with degenerative disc disease, facet joint arthrosis or spondylolisthesis will be included in the study and randomized into two groups: a control group undergoing conventional fusion surgery (PLIF - posterior lumbar intervertebral fusion), and an intervention group undergoing fusion surgery using a new flexible pedicle screw system (PLIF + "topping off"), which was brought on the market in 2013. Follow-up examination will take place immediately after surgery, after 6 weeks and after 6, 12, 24 and 36 months. An ongoing assessment will be performed every year.Outcome measurements will include quality of life and pain assessments using validated questionnaires (ODI - Ostwestry Disability Index, SF-36™ - Short Form Health Survey 36, COMI - Core Outcome Measure Index). In addition, clinical and radiologic ASD, sagittal balance parameters and duration of work disability will be assessed. Inpatient and 6-month mortality, surgery-related data (e.g., intraoperative complications, blood loss, length of incision, surgical duration), postoperative complications (e.g. implant failure), adverse events, and serious adverse events will be monitored and documented throughout the study. New hybrid "topping off" systems might improve the outcome of lumbar spine fusion. But to date, there is a serious lack of and a great need

  19. Advanced Communication Technology Satellite (ACTS) Very Small Aperture Terminal (VSAT) Network Control Performance

    Science.gov (United States)

    Coney, T. A.

    1996-01-01

    This paper discusses the performance of the network control function for the Advanced Communications Technology Satellite (ACTS) very small aperture terminal (VSAT) full mesh network. This includes control of all operational activities such as acquisition, synchronization, timing and rain fade compensation as well as control of all communications activities such as on-demand integrated services (voice, video, and date) connects and disconnects Operations control is provided by an in-band orderwire carried in the baseboard processor (BBP) control burst, the orderwire burst, the reference burst, and the uplink traffic burst. Communication services are provided by demand assigned multiple access (DAMA) protocols. The ACTS implementation of DAMA protocols ensures both on-demand and integrated voice, video and data services. Communications services control is also provided by the in-band orderwire but uses only the reference burst and the uplink traffic burst. The performance of the ACTS network control functions have been successfully tested during on-orbit checkout and in various VSAT networks in day to day operations. This paper discusses the network operations and services control performance.

  20. Using satellite data to guide emission control strategies for surface ozone pollution

    Science.gov (United States)

    Jin, X.; Fiore, A. M.

    2017-12-01

    Surface ozone (O3) has adverse effects on public health, agriculture and ecosystems. As a secondary pollutant, ozone is not emitted directly. Ozone forms from two classes of precursors: NOx and VOCs. We use satellite observations of formaldehyde (a marker of VOCs) and NO2 (a marker of NOx) to identify areas which would benefit more from reducing NOx emissions (NOx-limited) versus areas where reducing VOC emissions would lead to lower ozone (VOC-limited). We use a global chemical transport model (GEOS-Chem) to develop a set of threshold values that separate the NOx-limited and VOC-limited conditions. Combining these threshold values with a decadal record of satellite observations, we find that U.S. cities (e.g. New York, Chicago) have shifted from VOC-limited to NOx-limited ozone production regimes in the warm season. This transition reflects the NOx emission controls implemented over the past decade. Increasing NOx sensitivity implies that regional NOx emission control programs will improve O3 air quality more now than it would have a decade ago.

  1. Infection Control in Child Day Care Centres : Development and evaluation of a hand hygiene intervention

    NARCIS (Netherlands)

    T.P. Zomer (Tizza)

    2015-01-01

    markdownabstract__Abstract__ Children attending child day care centres are at increased risk of acquiring gastrointestinal and respiratory infections compared to children cared for at home. Hand hygiene is known to be an effective measure to prevent infections. However, compliance with hand

  2. Hematopoietic stem cell transplantation in Switzerland: a comprehensive quality control report on centre effect.

    Science.gov (United States)

    Passweg, Jakob; Baldomero, Helen; Stern, Martin; Bargetzi, Mario; Ghielmini, Michele; Leibundgut, Kurt; Duchosal, Michel; Hess, Urs; Seger, Reinhard; Buhrfeind, Eva; Schanz, Urs; Gratwohl, Alois

    2010-06-12

    Interest groups advocate centre-specific outcome data as a useful tool for patients in choosing a hospital for their treatment and for decision-making by politicians and the insurance industry. Haematopoietic stem cell transplantation (HSCT) requires significant infrastructure and represents a cost-intensive procedure. It therefore qualifies as a prime target for such a policy. We made use of the comprehensive database of the Swiss Blood Stem Cells Transplant Group (SBST) to evaluate potential use of mortality rates. Nine institutions reported a total of 4717 HSCT - 1427 allogeneic (30.3%), 3290 autologous (69.7%) - in 3808 patients between the years 1997 and 2008. Data were analysed for survival- and transplantation-related mortality (TRM) at day 100 and at 5 years. The data showed marked and significant differences between centres in unadjusted analyses. These differences were absent or marginal when the results were adjusted for disease, year of transplant and the EBMT risk score (a score incorporating patient age, disease stage, time interval between diagnosis and transplantation, and, for allogeneic transplants, donor type and donor-recipient gender combination) in a multivariable analysis. These data indicate comparable quality among centres in Switzerland. They show that comparison of crude centre-specific outcome data without adjustment for the patient mix may be misleading. Mandatory data collection and systematic review of all cases within a comprehensive quality management system might, in contrast, serve as a model to ascertain the quality of other cost-intensive therapies in Switzerland.

  3. Beach erosion control study at Pass Christian. [using remote sensors and satellite observation

    Science.gov (United States)

    1978-01-01

    The methods of measuring the existence of erosion and the effects of sand stabilization control systems are described. The mechanics of sand movement, the nature of sand erosion, and the use of satellite data to measure these factors and their surrogates are discussed using the locational and control aspects of aeolian and litoral erosion zones along the sand beach of the Mississippi coast. The aeolian erosion is highlighted due to the redeposition of the sand which causes high cleanup costs, property damage, and safety and health hazards. The areas of differential erosion and the patterns of beach sand movement are illustrated and the use of remote sensing methods to identify the areas of erosion are evaluated.

  4. Investigation of Separate Meter-In Separate Meter-Out Control Strategies for Systems with Over Centre Valves

    DEFF Research Database (Denmark)

    Pedersen, Henrik C.; Andersen, Torben Ole; Hansen, Rico Hjerm

    2010-01-01

    to overcome this problem, but it typically implies higher energy consumption and/or decreased control performance. With the development of robust sensors and new valve types with separate meter-in, separate meter-out control it is, however, possible to overcome these stability problems in a much more...... intelligent way, also adding increased functionality to the system. The focus of the current paper is therefore on investigation of different control strategies for Separate Meter-In Separate Meter-Out (SMISMO) control of general single axis hydraulic system with a differential cylinder and an over......-centre valve included. The paper first presents a general model of the system considered, which is experimentally verified. This is followed by a discussion of different control strategies and their implications. For each of the control strategies controllers are described, taking into account the dynamics...

  5. Guidance, Navigation, and Control System for Maneuverable Pico-Satellites, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — A compact, low-power GN&C system is essential to the success of pico-satellite Automated Rendezvous and Docking (AR&D). Austin Satellite Design (ASD)...

  6. Control of GABARAP-mediated autophagy by the Golgi complex, centrosome and centriolar satellites.

    Science.gov (United States)

    Joachim, Justin; Tooze, Sharon A

    2018-01-01

    Within minutes of induction of autophagy by amino-acid starvation in mammalian cells, multiple autophagosomes form throughout the cell cytoplasm. During their formation, the autophagosomes sequester cytoplasmic material and deliver it to lysosomes for degradation. How these organelles can be so rapidly formed and how their formation is acutely regulated are major questions in the autophagy field. Protein and lipid trafficking from diverse cell compartments contribute membrane to, or regulate the formation of the autophagosome. In addition, recruitment of Atg8 (in yeast), and the ATG8-family members (in mammalian cells) to autophagosomes is required for efficient autophagy. Recently, it was discovered that the centrosome and centriolar satellites regulate autophagosome formation by delivery of an ATG8-family member, GABARAP, to the forming autophagosome membrane, the phagophore. We propose that GABARAP regulates phagophore expansion by activating the ULK complex, the amino-acid controlled initiator complex. This finding reveals a previously unknown link between the centrosome, centriolar satellites and autophagy. © 2017 Société Française des Microscopies and Société de Biologie Cellulaire de France. Published by John Wiley & Sons Ltd.

  7. Control of effluents and environmental surveillance of the CEA centres. 1997 status

    International Nuclear Information System (INIS)

    1998-06-01

    The environmental quality in the vicinity of CEA facilities is a major concern of the safety policy of the CEA. The aim of this document is to inform the public about the gaseous and liquids radioactive effluents released by the CEA centres under the permission of the ministry. It provides a status of the effluents and of the radioactivity levels measured near the CEA centres in 1997, using air, water, vegetation and milk samples. A comparison is made with the measurements performed during the 1993-1996 period. The data presented comes from the regulatory registers transmitted to the agency for the protection against ionizing radiations (OPRI) which belongs to the ministry of health. (J.S.)

  8. Fast neutrons in the treatment of head and neck cancers: the results of a multi-centre randomly controlled trial

    International Nuclear Information System (INIS)

    Duncan, W.; Arnott, S.J.; Orr, J.A.; Kerr, G.R.; Schmitt, G.

    1984-01-01

    The results are presented of a multi-centre randomly controlled trial of fast neutron irradiation and mega-voltage X-rays in the treatment of patients with locally advanced squamous cell carcinoma of the head and neck region. No significant difference was observed in local tumour control rates. Salvage surgery was performed in a similar number of patients in the two groups. Late morbidity was also similar in the two treatment groups. Patients in a subgroup with cancer of the larynx treated by photons had a significantly better survival than those in the neutron treated group. (Auth.)

  9. Person-centred care after acute coronary syndrome, from hospital to primary care - A randomised controlled trial.

    Science.gov (United States)

    Fors, Andreas; Ekman, Inger; Taft, Charles; Björkelund, Cecilia; Frid, Kerstin; Larsson, Maria Eh; Thorn, Jörgen; Ulin, Kerstin; Wolf, Axel; Swedberg, Karl

    2015-01-01

    To evaluate if person-centred care can improve self-efficacy and facilitate return to work or prior activity level in patients after an event of acute coronary syndrome. 199 patients with acute coronary syndrome < 75 years were randomly assigned to person-centred care intervention or treatment as usual and followed for 6 months. In the intervention group a person-centred care process was added to treatment as usual, emphasising the patient as a partner in care. Care was co-created in collaboration between patients, physicians, registered nurses and other health care professionals and documented in a health plan. A team-based partnership across three health care levels included transparent knowledge about the disease and medical state to achieve agreed goals during recovery. Main outcome measure was a composite score of changes in general self-efficacy ≥ 5 units, return to work or prior activity level and re-hospitalisation or death. The composite score showed that more patients (22.3%, n=21) improved in the intervention group at 6 months compared to the control group (9.5%, n=10) (odds ratio, 2.7; 95% confidence interval: 1.2-6.2; P=0.015). The effect was driven by improved self-efficacy ≥ 5 units in the intervention group. Overall general self-efficacy improved significantly more in the intervention group compared with the control group (P=0.026). There was no difference between groups on re-hospitalisation or death, return to work or prior activity level. A person-centred care approach emphasising the partnership between patients and health care professionals throughout the care chain improves general self-efficacy without causing worsening clinical events. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  10. Performance experiments with alternative advanced teleoperator control modes for a simulated solar maximum satellite repair

    Science.gov (United States)

    Das, H.; Zak, H.; Kim, W. S.; Bejczy, A. K.; Schenker, P. S.

    1992-01-01

    Experiments are described which were conducted at the JPL Advanced Teleoperator Lab to demonstrate and evaluate the effectiveness of various teleoperator control modes in the performance of a simulated Solar Max Satellite Repair (SMSR) task. THe SMSR was selected as a test because it is very rich in performance capability requirements and it actually has been performed by two EVA astronauts in the Space Shuttle Bay in 1984. The main subtasks are: thermal blanket removal; installation of a hinge attachment for electrical panel opening; opening of electrical panel; removal of electrical connectors; relining of cable bundles; replacement of electrical panel; securing parts and cables; re-mate electrical connectors; closing of electrical panel; and reinstating thermal blanket. The current performance experiments are limited to thermal blanket cutting, electrical panel unbolting and handling electrical bundles and connectors. In one formal experiment even different control modes were applied to the unbolting and reinsertion of electrical panel screws subtasks. The seven control modes are alternative combinations of manual position and rate control with force feedback and remote compliance referenced to force-torque sensor information. Force-torque sensor and end effector position data and task completion times were recorded for analysis and quantification of operator performance.

  11. Satellite myths

    Science.gov (United States)

    Easton, Roger L.; Hall, David

    2008-01-01

    Richard Corfield's article “Sputnik's legacy” (October 2007 pp23-27) states that the satellite on board the US Vanguard rocket, which exploded during launch on 6 December 1957 two months after Sputnik's successful take-off, was “a hastily put together contraption of wires and circuitry designed only to send a radio signal back to Earth”. In fact, the Vanguard satellite was developed over a period of several years and put together carefully using the best techniques and equipment available at the time - such as transistors from Bell Laboratories/Western Electric. The satellite contained not one but two transmitters, in which the crystal-controlled oscillators had been designed to measure both the temperature of the satellite shell and of the internal package.

  12. Identifying and controlling a multiresistant pseudomonas aeruginosa outbreak in a latin-american cancer centre and its associated risk factors

    Directory of Open Access Journals (Sweden)

    Jorge Alberto Cortes

    Full Text Available Pseudomonas aeruginosa is an important and frightening microorganism for patients suffering from cancer. Multiresistant P. aeruginosa (MRPA may appear as a consequence of exposure to multiple antibiotics or from a breakdown in infection control practices. This article reports an MRPA outbreak in a cancer treatment centre and the consequent case control study. Mechanical ventilation was identified as being the main risk factor for developing MRPA colonisation or infection; molecular analysis confirmed the outbreak. A multifaceted strategy was adopted, involving reinforcing hand-washing practices, contact isolation, antibiotic restriction and suction devices for mechanically-ventilated patients. MRPA was controlled and the outbreak ended. Such strategy may be effective in controlling MRPS in low-resource environments amongst high risk cancer patients.

  13. 23rd June 2010 - University of Bristol Head of the Aerospace Engineering Department and Professor of Aerospace Dynamics N. Lieven visiting CERN control centre with Beams Department Head P. Collier, visiting the LHC superconducting magnet test hall with R. Veness and CMS control centre with Collaboration Spokesperson G. Tonelli and CMS User J. Goldstein.

    CERN Multimedia

    Jean-Claude Gadmer

    2010-01-01

    23rd June 2010 - University of Bristol Head of the Aerospace Engineering Department and Professor of Aerospace Dynamics N. Lieven visiting CERN control centre with Beams Department Head P. Collier, visiting the LHC superconducting magnet test hall with R. Veness and CMS control centre with Collaboration Spokesperson G. Tonelli and CMS User J. Goldstein.

  14. The Implementation of Satellite Attitude Control System Software Using Object Oriented Design

    Science.gov (United States)

    Reid, W. Mark; Hansell, William; Phillips, Tom; Anderson, Mark O.; Drury, Derek

    1998-01-01

    NASA established the Small Explorer (SNMX) program in 1988 to provide frequent opportunities for highly focused and relatively inexpensive space science missions. The SMEX program has produced five satellites, three of which have been successfully launched. The remaining two spacecraft are scheduled for launch within the coming year. NASA has recently developed a prototype for the next generation Small Explorer spacecraft (SMEX-Lite). This paper describes the object-oriented design (OOD) of the SMEX-Lite Attitude Control System (ACS) software. The SMEX-Lite ACS is three-axis controlled and is capable of performing sub-arc-minute pointing. This paper first describes high level requirements governing the SMEX-Lite ACS software architecture. Next, the context in which the software resides is explained. The paper describes the principles of encapsulation, inheritance, and polymorphism with respect to the implementation of an ACS software system. This paper will also discuss the design of several ACS software components. Specifically, object-oriented designs are presented for sensor data processing, attitude determination, attitude control, and failure detection. Finally, this paper will address the establishment of the ACS Foundation Class (AFC) Library. The AFC is a large software repository, requiring a minimal amount of code modifications to produce ACS software for future projects.

  15. ERROR-CONTROL CODING OF ADS-B MESSAGES FOR IRIDIUM SATELLITES

    Directory of Open Access Journals (Sweden)

    Volodymyr Kharchenko

    2013-12-01

    Full Text Available For modelling of ADS-B messages transmitting on the base of low-orbit satellite constellation Іrіdіum the model of a communication channel “Aircraft - Satellite - Ground Station” was built using MATLAB Sіmulіnk. This model allowed to investigate dependences of the Bit Error Rate on a type of  signal coding/decoding, ratio Eb/N0 and satellite repeater gain

  16. Energy control centres and traction power management of the OeBB infrastructure; Energieleitstellen und Traktionsstrommanagement der OeBB-Infrastruktur

    Energy Technology Data Exchange (ETDEWEB)

    Gammer, Michael; Heinze, Florian [OeBB-Infrastruktur AG, Vienna (Austria). Geschaeftsbereich Energie

    2013-04-15

    According to the OeBB control centre concept, the currently four operations management sites for the 15 kV railway power network will be reduced to just two locations which will be reoriented to operate as energy control centres. For the support of the operators, tools have been developed under the title traction power management, which are based on combined simulations of overhead line network and train operations. (orig.)

  17. Implementation of quality assurance and quality control in the Nuclear Analytical Laboratory of the Estonian Radiation Protection Centre

    International Nuclear Information System (INIS)

    Koeoep, T.; Jakobson, E.

    2002-01-01

    The Analytical Laboratory of the Estonian Radiation Protection Centre is in the process of implementing the system of Quality Assurance (QA) and Quality Control (QC) in the framework of the IAEA TC Project RER/2/004/ 'QA/QC of Nuclear Analytical Techniques'. The draft Quality Manual with annexes has been prepared accordingly to the ISO 17025 Guide, documents and other printed material delivered on the seminars of the project. The laboratory supply has been supplemented with necessary equipment for guaranteeing of quality. Proficiency testing included in the project has been performed successfully. (author)

  18. A track chamber with controlled heat centres as a vertex detector for very high energy physics experiments

    International Nuclear Information System (INIS)

    Shcherbakov, Yu.A.

    1989-01-01

    A high-pressure vertex detector for high energy experiments is proposed on the basis of development of a new track detector of charged particles, which is a chamber with controlled centres. A possible design of this chamber is discussed. Laser illumination of a streamer chamber allows enough light for reading the information by means of a CCD device. Some characteristics of the set-up are considered in the paper. A possibility of using a new method for suppression of diffusion is discussed. 30 refs.; 7 figs.; 3 tabs

  19. The Implementation of Satellite Control System Software Using Object Oriented Design

    Science.gov (United States)

    Anderson, Mark O.; Reid, Mark; Drury, Derek; Hansell, William; Phillips, Tom

    1998-01-01

    NASA established the Small Explorer (SMEX) program in 1988 to provide frequent opportunities for highly focused and relatively inexpensive space science missions that can be launched into low earth orbit by small expendable vehicles. The development schedule for each SMEX spacecraft was three years from start to launch. The SMEX program has produced five satellites; Solar Anomalous and Magnetospheric Particle Explorer (SAMPEX), Fast Auroral Snapshot Explorer (FAST), Submillimeter Wave Astronomy Satellite (SWAS), Transition Region and Coronal Explorer (TRACE) and Wide-Field Infrared Explorer (WIRE). SAMPEX and FAST are on-orbit, TRACE is scheduled to be launched in April of 1998, WIRE is scheduled to be launched in September of 1998, and SWAS is scheduled to be launched in January of 1999. In each of these missions, the Attitude Control System (ACS) software was written using a modular procedural design. Current program goals require complete spacecraft development within 18 months. This requirement has increased pressure to write reusable flight software. Object-Oriented Design (OOD) offers the constructs for developing an application that only needs modification for mission unique requirements. This paper describes the OOD that was used to develop the SMEX-Lite ACS software. The SMEX-Lite ACS is three-axis controlled, momentum stabilized, and is capable of performing sub-arc-minute pointing. The paper first describes the high level requirements which governed the architecture of the SMEX-Lite ACS software. Next, the context in which the software resides is explained. The paper describes the benefits of encapsulation, inheritance and polymorphism with respect to the implementation of an ACS software system. This paper will discuss the design of several software components that comprise the ACS software. Specifically, Object-Oriented designs are presented for sensor data processing, attitude control, attitude determination and failure detection. The paper addresses

  20. Glycaemic control of diabetic patients in an urban primary health care setting in Sarawak: the Tanah Puteh Health Centre experience.

    Science.gov (United States)

    Wong, J S; Rahimah, N

    2004-08-01

    Achieving glycaemic goals in diabetics has always been a problem, especially in a developing country with inadequate facilities such as in Sarawak in Malaysia. There are no reported studies on the control of diabetes mellitus in a diabetic clinic in the primary health care setting in Sarawak. This paper describes the profile of 1031 patients treated in Klinik Kesihatan Tanah Puteh Health Centre. The mean age was 59 years, the mean BMI 27 kg/m2. There was a female preponderance and mainly type-2 diabetes. Mean HbA1c was 7.4%. Glycaemic control was optimal in 28% (HbA1c 7.5%). Reasonable glycaemic control can be achieved in the primary health care setting in Sarawak.

  1. Low back pain and postural control, effects of task difficulty on centre of pressure and spinal kinematics.

    Science.gov (United States)

    Schelldorfer, Sarah; Ernst, Markus Josef; Rast, Fabian Marcel; Bauer, Christoph Michael; Meichtry, André; Kool, Jan

    2015-01-01

    Association of low back pain and standing postural control (PC) deficits are reported inconsistently. Demands on PC adaptation strategies are increased by restraining the input of visual or somatosensory senses. The objectives of the current study are, to investigate whether PC adaptations of the spine, hip and the centre of pressure (COP) differ between patients reporting non-specific low back pain (NSLBP) and asymptomatic controls. The PC adaption strategies of the thoracic and lumbar spine, the hip and the COP were measured in fifty-seven NSLBP patients and 22 asymptomatic controls. We tested three "feet together" conditions with increasing demands on PC strategies, using inertial measurement units (IMUs) on the spine and a Wii balance board for centre of pressure (COP) parameters. The differences between NSLBP patients and controls were most apparent when the participants were blindfolded, but remaining on a firm surface. While NSLBP patients had larger thoracic and lumbar spine mean absolute deviations of position (MADpos) in the frontal plane, the same parameters decreased in control subjects (relative change (RC): 0.23, 95% confidence interval: 0.03 to 0.45 and 0.03 to 0.48). The Mean absolute deviation of velocity (MADvel) of the thoracic spine in the frontal plane showed a similar and significant effect (RC: 0.12 95% CI: 0.01 to 0.25). Gender, age and pain during the measurements affected some parameters significantly. PC adaptions differ between NSLBP patients and asymptomatic controls. The differences are most apparent for the thoracic and lumbar parameters of MADpos, in the frontal plane and while the visual condition was removed. Copyright © 2014 Elsevier B.V. All rights reserved.

  2. GPS Satellite Simulation Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The GPS satellite simulation facility consists of a GPS satellite simulator controlled by either a Silicon Graphics Origin 2000 or PC depending upon unit under test...

  3. Autonomous Satellite Command and Control Through the World Wide Web. Phase 3

    Science.gov (United States)

    Cantwell, Brian; Twiggs, Robert

    1998-01-01

    The Automated Space System Experimental Testbed (ASSET) system is a simple yet comprehensive real-world operations network being developed. Phase 3 of the ASSET Project was January-December 1997 and is the subject of this report. This phase permitted SSDL and its project partners to expand the ASSET system in a variety of ways. These added capabilities included the advancement of ground station capabilities, the adaptation of spacecraft on-board software, and the expansion of capabilities of the ASSET management algorithms. Specific goals of Phase 3 were: (1) Extend Web-based goal-level commanding for both the payload PI and the spacecraft engineer. (2) Support prioritized handling of multiple (PIs) Principle Investigators as well as associated payload experimenters. (3) Expand the number and types of experiments supported by the ASSET system and its associated spacecraft. (4) Implement more advanced resource management, modeling and fault management capabilities that integrate the space and ground segments of the space system hardware. (5) Implement a beacon monitoring test. (6) Implement an experimental blackboard controller for space system management. (7) Further define typical ground station developments required for Internet-based remote control and for full system automation of the PI-to-spacecraft link. Each of those goals are examined. Significant sections of this report were also published as a conference paper. Several publications produced in support of this grant are included as attachments. Titles include: 1) Experimental Initiatives in Space System Operations; 2) The ASSET Client Interface: Balancing High Level Specification with Low Level Control; 3) Specifying Spacecraft Operations At The Product/Service Level; 4) The Design of a Highly Configurable, Reusable Operating System for Testbed Satellites; 5) Automated Health Operations For The Sapphire Spacecraft; 6) Engineering Data Summaries for Space Missions; and 7) Experiments In Automated Health

  4. Childhood obesity prevention and control in city recreation centres and family homes: the MOVE/me Muevo Project.

    Science.gov (United States)

    Elder, J P; Crespo, N C; Corder, K; Ayala, G X; Slymen, D J; Lopez, N V; Moody, J S; McKenzie, T L

    2014-06-01

    Interventions to prevent and control childhood obesity have shown mixed results in terms of short- and long-term changes. 'MOVE/me Muevo' was a 2-year family- and recreation centre-based randomized controlled trial to promote healthy eating and physical activity among 5- to 8-year-old children. It was hypothesized that children in the intervention group would demonstrate lower post-intervention body mass index (BMI) values and improved obesity-related behaviours compared with the control group children. Thirty recreation centres in San Diego County, California, were randomized to an intervention or control condition. Five hundred forty-one families were enrolled and children's BMI, diet, physical activity and other health indicators were tracked from baseline to 2 years post-baseline. Analyses followed an intent-to-treat approach using mixed-effects models. No significant intervention effects were observed for the primary outcomes of child's or parent's BMI and child's waist circumference. Moderator analyses, however, showed that girls (but not boys) in the intervention condition reduced their BMI. At the 2-year follow-up, intervention condition parents reported that their children were consuming fewer high-fat foods and sugary beverages. Favourable implementation fidelity and high retention rates support the feasibility of this intervention in a large metropolitan area; however, interventions of greater intensity may be needed to achieve effects on child's BMI. Also, further research is needed to develop gender-specific intervention strategies so that both genders may benefit from such efforts. © 2013 The Authors. Pediatric Obesity © 2013 International Association for the Study of Obesity.

  5. Pilates based core stability training in ambulant individuals with multiple sclerosis: protocol for a multi-centre randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Freeman Jennifer

    2012-04-01

    Full Text Available Abstract Background People with Multiple Sclerosis (MS frequently experience balance and mobility impairments, including reduced trunk stability. Pilates-based core stability training, which is aimed at improving control of the body's stabilising muscles, is popular as a form of exercise with people with MS and therapists. A replicated single case series study facilitated by the Therapists in MS Group in the United Kingdom (UK provides preliminary evidence that this approach can improve balance and mobility in ambulant people with MS; further evidence is needed to substantiate these findings to ensure that limited time, energy, finances and resources are used to best effect. This study builds upon the pilot work undertaken in the case series study by implementing a powered randomised controlled study, with the aims of: 1 Establishing the effectiveness of core stability training 2 Comparing core stability training with standardised physiotherapy exercise 3 Exploring underlying mechanisms of change associated with this intervention Methods This is a multi-centre, double blind, block randomised, controlled trial. Eligible participants will be recruited from 4 UK centres. Participants will be randomly allocated to one of three groups: Pilates based core stability training, standardised physiotherapy exercise or contract-relax relaxation sessions (placebo control. All will receive face to face training sessions over a 12 week period; together with a 15 minute daily home programme. All will be assessed by a blinded assessor before training, at the end of the 12 week programme and at 4 week follow-up. The primary outcome measure is the 10 metre timed walk. Secondary outcome measures are the MS walking Scale (MSWS-12, the Functional Reach (forwards and lateral, a 10 point Numerical Rating Scale to determine "Difficulty in carrying a drink when walking", and the Activities-specific Balance Confidence (ABC Scale. In addition, ultrasound imaging of the

  6. Pilates based core stability training in ambulant individuals with multiple sclerosis: protocol for a multi-centre randomised controlled trial.

    Science.gov (United States)

    Freeman, Jennifer; Fox, Esther; Gear, Margaret; Hough, Alan

    2012-04-05

    People with Multiple Sclerosis (MS) frequently experience balance and mobility impairments, including reduced trunk stability. Pilates-based core stability training, which is aimed at improving control of the body's stabilising muscles, is popular as a form of exercise with people with MS and therapists. A replicated single case series study facilitated by the Therapists in MS Group in the United Kingdom (UK) provides preliminary evidence that this approach can improve balance and mobility in ambulant people with MS; further evidence is needed to substantiate these findings to ensure that limited time, energy, finances and resources are used to best effect.This study builds upon the pilot work undertaken in the case series study by implementing a powered randomised controlled study, with the aims of: 1 Establishing the effectiveness of core stability training; 2 Comparing core stability training with standardised physiotherapy exercise; 3 Exploring underlying mechanisms of change associated with this intervention This is a multi-centre, double blind, block randomised, controlled trial. Eligible participants will be recruited from 4 UK centres. Participants will be randomly allocated to one of three groups: Pilates based core stability training, standardised physiotherapy exercise or contract-relax relaxation sessions (placebo control). All will receive face to face training sessions over a 12 week period; together with a 15 minute daily home programme. All will be assessed by a blinded assessor before training, at the end of the 12 week programme and at 4 week follow-up. The primary outcome measure is the 10 metre timed walk. Secondary outcome measures are the MS walking Scale (MSWS-12), the Functional Reach (forwards and lateral), a 10 point Numerical Rating Scale to determine "Difficulty in carrying a drink when walking", and the Activities-specific Balance Confidence (ABC) Scale. In addition, ultrasound imaging of the abdominal muscles will be performed before

  7. Integrating of renewable energy in operation system: the Special Regime Control Centre (CECRE); Integracion de la energia renovable en la operacion del sistema: El Centro de Control de regimen especial (CECRE)

    Energy Technology Data Exchange (ETDEWEB)

    Division, M.

    2007-07-01

    The implementation of Red Electrica de Espana Special Regime Control Centre (CECRE) has demonstrated the Spanish System Operators commitment of integrating the maximum possible wind power generation into the electrical system compatible with secure operation. With this leadership initiative,for the first time in the world, a System Operator Control Centre (CECRE) has succeeded in sending power control instructions to wind power generators over the country through Generation Control Centres (CGC) to which these generators must be connected complying with the Spanish Rules. (Author)

  8. Some analytical methods used by the Marcoule Centre for the control of radioactive effluents; Quelques methodes analytiques, utilisees sur le centre de Marcoule pour le controle radioactif des effluents

    Energy Technology Data Exchange (ETDEWEB)

    Scheidhauer, J.; Messainguiral, L.; Drogue, N.; Meiranesio, A. M.

    1962-07-09

    After three years of operation, the authors propose a review of the various methods used to determine the radioactivity of wastewaters released by the Marcoule Centre Laboratory. They describe the three main steps of this control: firstly, measurements of the global alpha radioactivity and beta radioactivity (principle and measurement method), secondly, dosing of strontium 89 and strontium 90 (principle, used reactants, operation mode for nitric compound precipitation, ferric decontamination, separation of barium 140, oxalic precipitation, precipitate counting, exploitation of counting results), and thirdly, the possible dosing of other fission products present in the effluents: cerium 144, plutonium (by two different methods), natural uranium, caesium 137, zirconium 95, niobium 95, ruthenium 103 and 106, iodine 131. The principle, reactants, operational mode with different precipitations, measurement devices are indicated for each of these radio-elements.

  9. Satellite image collection optimization

    Science.gov (United States)

    Martin, William

    2002-09-01

    Imaging satellite systems represent a high capital cost. Optimizing the collection of images is critical for both satisfying customer orders and building a sustainable satellite operations business. We describe the functions of an operational, multivariable, time dynamic optimization system that maximizes the daily collection of satellite images. A graphical user interface allows the operator to quickly see the results of what if adjustments to an image collection plan. Used for both long range planning and daily collection scheduling of Space Imaging's IKONOS satellite, the satellite control and tasking (SCT) software allows collection commands to be altered up to 10 min before upload to the satellite.

  10. HEXIM1 controls satellite cell expansion after injury to regulate skeletal muscle regeneration

    Science.gov (United States)

    Hong, Peng; Chen, Kang; Huang, Bihui; Liu, Min; Cui, Miao; Rozenberg, Inna; Chaqour, Brahim; Pan, Xiaoyue; Barton, Elisabeth R.; Jiang, Xian-Cheng; Siddiqui, M.A.Q.

    2012-01-01

    The native capacity of adult skeletal muscles to regenerate is vital to the recovery from physical injuries and dystrophic diseases. Currently, the development of therapeutic interventions has been hindered by the complex regulatory network underlying the process of muscle regeneration. Using a mouse model of skeletal muscle regeneration after injury, we identified hexamethylene bisacetamide inducible 1 (HEXIM1, also referred to as CLP-1), the inhibitory component of the positive transcription elongation factor b (P-TEFb) complex, as a pivotal regulator of skeletal muscle regeneration. Hexim1-haplodeficient muscles exhibited greater mass and preserved function compared with those of WT muscles after injury, as a result of enhanced expansion of satellite cells. Transplanted Hexim1-haplodeficient satellite cells expanded and improved muscle regeneration more effectively than WT satellite cells. Conversely, HEXIM1 overexpression restrained satellite cell proliferation and impeded muscle regeneration. Mechanistically, dissociation of HEXIM1 from P-TEFb and subsequent activation of P-TEFb are required for satellite cell proliferation and the prevention of early myogenic differentiation. These findings suggest a crucial role for the HEXIM1/P-TEFb pathway in the regulation of satellite cell–mediated muscle regeneration and identify HEXIM1 as a potential therapeutic target for degenerative muscular diseases. PMID:23023707

  11. Radiation protection control report for the research centre Seibersdorf for the year 2001

    International Nuclear Information System (INIS)

    Mueck, K.; Urbanich, E.; Abzieher, F.; Hefner, A.; Lechner, C.; Lovranich, E.; Steger, F.; Tuechler, W.; Wihlidal, H.

    2002-05-01

    In order to prove that workers and the environment of the Research Centre Seibersdorf are not exposed to undue radiation exposures, an extensive program of evidence monitoring is carried out in and around the Research Centre Seibersdorf. The program ranges from workers' surveillance on external and internal radiation exposure via the monitoring of working places and laboratories with regard to external dose rate, surface contamination and activity concentration in air, the surveillance of releases to immersion monitoring with regard to external dose rate and activity concentrations in the vicinity of the Research Center. The present report comprises a summary of the results of this radiation exposure surveillance of workers and the vicinity of the Research Center in the year 2001. The average radiation exposure of all surveyed persons in the year 2001 was 1.41 mSv including background radiation (1.09 mSv). Subtracting this natural background level, the net annual dose amounts to 0.32 mSv corresponding to 1.6 % of the limit for occupationally exposed persons. In the past year no surpassing of dose limits was observed. The maximum dose of a single worker was 5.46 mSv/a (27 % of the legal limit of 20 mSv/a). Workers which were occupied with open radioactive substances, were surveyed for incorporation. They showed no incorporations above limits, in most surveyed cases no incorporation at all was detected. Releases to the environment were, as in the past years, below limits set by the authorities, generally by orders of magnitude. For the shut-down research reactor for which the release monitoring was continued, the releases in the year 2001 amounted to 0.13 %, for the incineration plant to 0.11 % (alpha-emitters) and 0.0038 % (beta-emitters), for the Safeguard Analytical Laboratory to 3.2 % (alpha-emitters) and 0.67 % (beta-emitters), for the Hot Cell Laboratory to 3.0 % (alpha-emitters) and 0.4 (beta-emitters), and the radiopharmaceutical facility 0.02 % for 131 I and

  12. RPAS ADS-B AND TRAJECTORY CONTROL DATA TRANSMISSION VIA SATELLITE

    Directory of Open Access Journals (Sweden)

    Andrii Grekhov

    2017-11-01

    Full Text Available Purpose: to develop a model of the satellite communication channel for an remotely piloted air system with adaptive modulation and orthogonal frequency division of channels; 2 to calculate the channel parameters with Rayleigh fading and various types of satellite transponder nonlinearity; 3 analyze the effect of fading and the type of nonlinearity on the parameters of the satellite communication channel. Method: MATLAB Simulink software was used to simulate the channel operation. Results: For the first time, based on the IEEE 802.16d standard, a realistic model of the satellite communication channel of an unmanned aerial vehicle was developed, which is used to estimate the channel parameters. The created model takes into account the Rayleigh fading in the downlink and the nonlinearity of the satellite transponder amplifier. Dependences of the signal-to-noise ratio in the terrestrial receiver on the signal-to-noise ratio in the downlink for various types of modulation (BPSK, QPSK, 16QAM, 64QAM and data transmission rates are obtained. The nonlinearity of satellite amplifiers was analyzed on the basis of a linear model, a cubic polynomial model, a hyperbolic tangential model, the Gorbani model, and the Rapp model. The results for the cubic polynomial model and the hyperbolic tangential model are similar to the linear model, but differ significantly from the Gorbani model and the Rapp model. For the Gorbani and Rapp models, very low values of the signal-to-noise ratio in the receiver are observed. Conclusion: The proposed approach can be considered as a method of estimating the parameters of the satellite communication channel of an unmanned aerial vehicle with fading. It is shown how the type of modulation varies depending on the level of the signal-to-noise ratio and the type of fading. The developed model allows to predict the operation of the channel with Rayleigh fading and can be useful for the design of communication systems.

  13. Development of quality control procedures at a new radiation therapy centre

    International Nuclear Information System (INIS)

    Cooper, A.

    1999-01-01

    Before patients can be treated with radiation therapy, the radiation therapist must be certain that the equipment is functioning within specified parameters. When commencing a new service, introducing appropriate Quality Control procedures on all equipment can be a major accomplishment. At the North Queensland Oncology Service, the Radiation Therapists are responsible for the daily Quality Control on all the radiation therapy equipment. The documentation and procedures were developed by radiation therapists to ensure that all machine parameter discrepancies would be detected before a patient was treated. Monthly Quality Control is the responsibility of the Physics Department. These are carried out on the bi-weekly service days rostered for each linear accelerator and monthly for the simulator. Ongoing Quality Control and Maintenance Meetings ensures reporting and feedback is ongoing between the Radiation Therapists and Physicists. All other liaising is done through the Deputy Chief Radiation Therapist and Senior Physicist. Copyright (1999) Australian Institute of Radiography

  14. Optimizing cognitive task load in naval ship control centres: Design of an adaptive interface

    NARCIS (Netherlands)

    Grootjen, M.; Bierman, E.P.B.; Neerincx, M.A.

    2006-01-01

    In the last 2 decades, major changes in information technology have taken place. In process control, the ongoing automation and the application of new technologies caused a radical change in the position of the operator. Combined with manning constraints, and the ever increasing pressure to maximize

  15. Quality Control of Boar Sperm Processing : Implications from European AI Centres and Two Spermatology Reference Laboratories

    NARCIS (Netherlands)

    Riesenbeck, A; Schulze, M; Rüdiger, K; Henning, H; Waberski, D

    In recent years, increased automatization has resulted in a higher efficiency of boar semen processing in AI laboratories. Sophisticated laboratory management and efficient quality control programmes are needed for current tendencies in major pork-producing countries to reduce the sperm number per

  16. Blood phenylalanine control in phenylketonuria : a survey of 10 European centres

    NARCIS (Netherlands)

    Ahring, K.; Belanger-Quintana, A.; Dokoupil, K.; Gokmen-Ozel, H.; Lammardo, A. M.; MacDonald, A.; Motzfeldt, K.; Nowacka, M.; van Rijn, M.; Robert, M.

    Background: Only limited data are available on the blood phenylalanine (Phe) concentrations achieved in European patients with phenylketonuria (PKU) on a low-Phe diet. Objective: A survey was conducted to compare blood Phe control achieved in diet-treated patients with PKU of different age groups in

  17. Robust Fault-Tolerant Control for Satellite Attitude Stabilization Based on Active Disturbance Rejection Approach with Artificial Bee Colony Algorithm

    Directory of Open Access Journals (Sweden)

    Fei Song

    2014-01-01

    Full Text Available This paper proposed a robust fault-tolerant control algorithm for satellite stabilization based on active disturbance rejection approach with artificial bee colony algorithm. The actuating mechanism of attitude control system consists of three working reaction flywheels and one spare reaction flywheel. The speed measurement of reaction flywheel is adopted for fault detection. If any reaction flywheel fault is detected, the corresponding fault flywheel is isolated and the spare reaction flywheel is activated to counteract the fault effect and ensure that the satellite is working safely and reliably. The active disturbance rejection approach is employed to design the controller, which handles input information with tracking differentiator, estimates system uncertainties with extended state observer, and generates control variables by state feedback and compensation. The designed active disturbance rejection controller is robust to both internal dynamics and external disturbances. The bandwidth parameter of extended state observer is optimized by the artificial bee colony algorithm so as to improve the performance of attitude control system. A series of simulation experiment results demonstrate the performance superiorities of the proposed robust fault-tolerant control algorithm.

  18. Controle optique de qubits lies a des centres isoelectroniques d'azote dans le GaAs

    Science.gov (United States)

    Ethier-Majcher, Gabriel

    Le traitement de l'information quantique est un domaine de recherche actuellement en pleine effervescence car il laisse entrevoir une revolution dans notre facon de traiter et d'echanger de l'information. D'une part, l'ordinateur quantique promet de resoudre des problemes comme la factorisation d'un polynome de facon beaucoup plus efficace qu'un ordinateur classique. D'autre part, les communications quantiques promettent l'echange d'information de facon fondamentalement inviolable. Afin de tirer pleinement profit de ces nouvelles technologies, il sera avantageux de construire des reseaux quantiques. Dans un tel reseau, des processeurs quantiques, les noeuds, seront connectes par des photons voyageant dans des fibres optiques. Les reseaux quantiques permettront de deployer les communications quantiques a grande echelle et de creer des super-ordinateurs quantiques. La realisation de reseaux quantiques necessitera des interfaces optiques pouvant echanger l'information de facon coherente entre un qubit (bit d'information quantique) et un photon. L'implementation de telles interfaces dans un systeme physique s'avere un important defi scientifique et technologique. Or, les systemes actuellement envisages a cette fin souffrent d'un faible couplage avec la lumiere ou encore de grandes inhomogeneites, constituant des obstacles a la realisation de reseaux a grande echelle. Dans cette these, le potentiel des centres isoelectroniques pour realiser des interfaces optiques est evalue. Deux types de qubits lies a des paires d'azote dans le GaAs sont consideres : les qubits excitoniques et les qubits de spin electronique, controlables par l'intermediaire d'excitons charges. Le controle optique complet des qubits excitoniques est demontre, ce qui constitue la premiere realisation du genre dans les centres isoelectroniques. L'observation d'excitons charges dans ce systeme, liant a la fois des trous lourds et des trous legers, laisse entrevoir de nouvelles possibilites afin de

  19. A nested case-control study of predictors for tuberculosis recurrence in a large UK Centre.

    Science.gov (United States)

    Rosser, Andrew; Richardson, Matthew; Wiselka, Martin J; Free, Robert C; Woltmann, Gerrit; Mukamolova, Galina V; Pareek, Manish

    2018-02-27

    Tuberculosis (TB) recurrence represents a challenge to control programs. In low incidence countries, the prevailing risk factors leading to recurrence are poorly characterised. We conducted a nested case-control study using the Leicester TB service TBIT database. Cases were identified from database notifications between 1994 and 2014. Controls had one episode and were matched to cases on a ratio of two to one by the date of notification. Multiple imputation was used to account for missing data. Multivariate conditional logistic regression analysis was employed to identify clinical, sociodemographic and TB specific risk factors for recurrence. From a cohort of 4628 patients, 82 TB recurrences occurred (1.8%). Nineteen of 82 patients had paired isolates with MIRU-VNTR strain type profiles available, of which 84% were relapses and 16% reinfections. On multivariate analysis, smoking (OR 3.8; p = 0.04), grade 3/4 adverse drug reactions (OR 5.6; p = 0.02), ethnicity 'Indian subcontinent' (OR 8.5; p = <0.01), ethnicity 'other' (OR 31.2; p = 0.01) and receipt of immunosuppressants (OR 6.8; p = <0.01) were independent predictors of TB recurrence. Within this UK setting, the rate of TB recurrence was low, predominantly due to relapse. The identification of an elevated recurrence risk amongst the ethnic group contributing most cases to the national TB burden presents an opportunity to improve individual and population health.

  20. Discussions on attitude determination and control system for micro/nano/pico-satellites considering survivability based on Hodoyoshi-3 and 4 experiences

    Science.gov (United States)

    Nakasuka, Shinichi; Miyata, Kikuko; Tsuruda, Yoshihiro; Aoyanagi, Yoshihide; Matsumoto, Takeshi

    2018-04-01

    The recent advancement of micro/nano/pico-satellites technologies encourages many universities to develop three axis stabilized satellites. As three axis stabilization is high level technology requiring the proper functioning of various sensors, actuators and control software, many early satellites failed in their initial operation phase because of shortage of solar power generation or inability to realize the initial step of missions because of unexpected attitude control system performance. These results come from failure to design the satellite attitude determination and control system (ADCS) appropriately and not considering "satellite survivability." ADCS should be designed such that even if some sensors or actuators cannot work as expected, the satellite can survive and carry out some of its missions, even if not full. This paper discusses how to realize ADCS while taking satellite survivability into account, based on our experiences of design and in-orbit operations of Hodoyoshi-3 and 4 satellites launched in 2014, which suffered from various component anomalies but could complete their missions.

  1. Satellite Dynamics and Control in a Quaternion Formulation (2nd edition)

    DEFF Research Database (Denmark)

    Blanke, Mogens; Larsen, Martin Birkelund

    to represent rotation. A general linearised model is derived such that the user can specify an arbitrary point of operation in angular velocity and wheel angular momentum, specifying the a inertia matrix for a rigid satellite. A set of Simulink® models that simulate the satellite’s nonlinear behaviour...

  2. 6th July 2010 - United Kingdom Science and Technology Facilities Council W. Whitehorn signing the guest book with Head of International relations F. Pauss, visiting the Computing Centre with Information Technology Department Head Deputy D. Foster, the LHC superconducting magnet test hall with Technology Department P. Strubin,the Centre Control Centre with Operation Group Leader M. Lamont and the CLIC/CTF3 facility with Project Leader J.-P. Delahaye.

    CERN Multimedia

    Teams : M. Brice, JC Gadmer

    2010-01-01

    6th July 2010 - United Kingdom Science and Technology Facilities Council W. Whitehorn signing the guest book with Head of International relations F. Pauss, visiting the Computing Centre with Information Technology Department Head Deputy D. Foster, the LHC superconducting magnet test hall with Technology Department P. Strubin,the Centre Control Centre with Operation Group Leader M. Lamont and the CLIC/CTF3 facility with Project Leader J.-P. Delahaye.

  3. Quality control at the Regional Centre of Nuclear Sciences chemical dosimetry laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Vivianne L.B. de; Melo, Roberto T. de; Silva, Danubia B. da; Pedroza, Eryka H.; Rodrigues, Kelia R.G.; Cunha, Manuela S. da; Figueiredo, Marcela D.C. de [Centro Regional de Ciencias Nucleares (CRCN-NE/CNEN-PE), Recife, PE (Brazil); Oliveira, Aristides, E-mail: vlsouza@cnen.gov.b, E-mail: rtmelo@cnen.gov.b [Hospital de Cancer de Pernambuco, Recife, PE (Brazil)

    2011-07-01

    Standards for accreditation of laboratories as in ISO 9001 in section: 4.11 require inspection, measuring and equipment testing; likewise, IEC 17025: 2005 in section: 5.5.2 requires the equipment to be calibrated or verified before being put into use. In our laboratory, quality control is often accomplished by standards set done by the laboratory scientists themselves; however, at present, Hellma secondary calibration standards (4026 - Holmium oxide - Filters: F0, F2, F3, F4 and filter didymium - F7) have been used in order to verify if errors in the laboratory have been close to the 1-2% margin. Control graphs were made by using the results of synthetically prepared standards and standardized spectral calibration certificates. The set of secondary calibration standards permits to check the accuracy of the spectrophotometers used in research for both the absorbance in the visible spectrum (at 440, 465, 546, 590 and 635 nm wavelengths) and for the wavelengths (270, 280, 300, 320 nm) of the ultraviolet light. Filters (F0, F2, F3, F4 and F7) are stable and do not suffer the influence of temperature (the influence is negligible), the F0 filter was being used as a blank. The purpose is to verify whether the spectrometer needs adjustments, an important procedure to check absorbance stability, baseline flatness, slit width accuracy and stray radiation. The calibration tests are performed annually in our laboratory and recalibration of Hellma secondary standards is recommended every two years. The results show that the Chemical Dosimetry Laboratory in CRCN has a calibrated spectrophotometer and their synthetic standards for Fricke dosimetry could be used as an alternative method for testing the proficiency and competence of calibration laboratories in accordance with the regulations and standards. (author)

  4. Outbreak investigation and control case report of brucellosis: Experience from livestock research centre, Mpwapwa, Tanzania

    Directory of Open Access Journals (Sweden)

    Gabriel M. Shirima

    2014-11-01

    Full Text Available Brucellosis screening was conducted between 2005 and 2010 at the National Livestock Research Institute headquarters, Mpwapwa, Tanzania, following an abortion storm in cattle. The initial screening targeted breeding herds; 483 cattle were screened using the Rose Bengal Plate Test (RBPT followed by the Competitive Enzyme-linked Immunosorbent Assay (c-ELISA as a confirmatory test. The seropositivity on c-ELISA was 28.95% in 2005; it subsequently declined to 6.72%, 1.17%, 0.16% and 0.00% in 2006, 2007, 2009 and 2010, respectively. Brucella seropositivity was not detected in goats. Seropositivity declined following institution of stringent control measures that included: gradual culling of seropositive animals through slaughter; isolation and confinement of pregnant cows close to calving; proper disposal of placentas and aborted foetuses; the use of the S19 vaccine; and restricted introduction of new animals. It was thought that the source of this outbreak was likely to have been from the introduction of infected animals from another farm. Furthermore, humans were found with brucellosis antibodies. Out of 120 people screened, 12 (10% were confirmed seropositive to brucella antigen exposure by c-ELISA analysis. The majority of the seropositive individuals (80% were milkers and animal handlers from the farm. Nine individuals had clinical signs suggestive of brucellosis. All cases received medical attention from the district hospital. This achievement in livestock and human health showed that it is possible to control brucellosis in dairy farms, compared to pastoral and agro-pastoral farms, thus providing evidence to adopt these strategies in dairy farms thought to be at risk.

  5. Comparison of tincture of opium and methadone to control opioid withdrawal in a Thai treatment centre

    Science.gov (United States)

    Jittiwutikarn, Jaroon; Ali, Robert; White, Jason M; Bochner, Felix; Somogyi, Andrew A; Foster, David J R

    2004-01-01

    Aims To evaluate the effectiveness of oral tincture of opium (TOP) and methadone to control opioid withdrawal in patients in northern Thailand. Methods Open label, parallel group study in an inpatient facility compared 15 former heroin users receiving methadone 5–20 mg 12 hourly with 15 former opium smokers receiving TOP (3.33–10 mg morphine equivalents 12 hourly). At 0, 1, 3 and 8 h, blood, withdrawal scores and subjective opioid effects were collected. Results There was a reciprocal association between withdrawal scores/direct subjective opioid effects and plasma (R)-methadone, but not plasma morphine, concentrations. Withdrawal scores at the time of dosing were higher in the TOP patients (9.1 ± 3) than in the methadone patients (4.5 ± 4.6) and in the TOP patients were significantly (P = 0.001) attenuated at 3 and 8 h. Conclusions At the doses used, TOP was inferior to methadone in suppressing withdrawal. It could prove to be a cost effective and valuable drug, but only after dose size and frequency are further investigated. PMID:15521902

  6. An elementary components of variance analysis for multi-centre quality control

    International Nuclear Information System (INIS)

    Munson, P.J.; Rodbard, D.

    1978-01-01

    The serious variability of RIA results from different laboratories indicates the need for multi-laboratory collaborative quality-control (QC) studies. Simple graphical display of data in the form of histograms is useful but insufficient. The paper discusses statistical analysis methods for such studies using an ''analysis of variance with components of variance estimation''. This technique allocates the total variance into components corresponding to between-laboratory, between-assay, and residual or within-assay variability. Problems with RIA data, e.g. severe non-uniformity of variance and/or departure from a normal distribution violate some of the usual assumptions underlying analysis of variance. In order to correct these problems, it is often necessary to transform the data before analysis by using a logarithmic, square-root, percentile, ranking, RIDIT, ''Studentizing'' or other transformation. Ametric transformations such as ranks or percentiles protect against the undue influence of outlying observations, but discard much intrinsic information. Several possible relationships of standard deviation to the laboratory mean are considered. Each relationship corresponds to an underlying statistical model and an appropriate analysis technique. Tests for homogeneity of variance may be used to determine whether an appropriate model has been chosen, although the exact functional relationship of standard deviation to laboratory mean may be difficult to establish. Appropriate graphical display aids visual understanding of the data. A plot of the ranked standard deviation versus ranked laboratory mean is a convenient way to summarize a QC study. This plot also allows determination of the rank correlation, which indicates a net relationship of variance to laboratory mean

  7. The Aube centre

    International Nuclear Information System (INIS)

    1996-07-01

    This educational booklet is devoted to a general presentation of the Aube radioactive wastes storage centre. After a short presentation of the Andra, the French national agency for the management of radioactive wastes, it gives some general information about radioactive wastes (origin, classification), containers (quality assurance and different types), wastes transportation (planning, safety), and about the Aube centre itself: description, treatment and conditioning of drums (compacting and injection), storage facilities, geological situation of the site, and environmental controls. (J.S.)

  8. The study protocol for a randomized controlled trial of a family-centred tobacco control program about environmental tobacco smoke (ETS to reduce respiratory illness in Indigenous infants

    Directory of Open Access Journals (Sweden)

    Segan Catherine

    2010-03-01

    Full Text Available Abstract Background Acute respiratory illness (ARI is the most common cause of acute presentations and hospitalisations of young Indigenous children in Australia and New Zealand (NZ. Environmental tobacco smoke (ETS from household smoking is a significant and preventable contributor to childhood ARI. This paper describes the protocol for a study which aims to test the efficacy of a family-centred tobacco control program about ETS to improve the respiratory health of Indigenous infants in Australia and New Zealand. For the purpose of this paper 'Indigenous' refers to Australia's Aboriginal and Torres Strait Islander peoples when referring to Australian Indigenous populations. In New Zealand, the term 'Indigenous' refers to Māori. Methods/Design This study will be a parallel, randomized, controlled trial. Participants will be Indigenous women and their infants, half of whom will be randomly allocated to an 'intervention' group, who will receive the tobacco control program over three home visits in the first three months of the infant's life and half to a control group receiving 'usual care' (i.e. they will not receive the tobacco control program. Indigenous health workers will deliver the intervention, the goal of which is to reduce or eliminate infant exposure to ETS. Data collection will occur at baseline (shortly after birth and when the infant is four months and one year of age. The primary outcome is a doctor-diagnosed, documented case of respiratory illness in participating infants. Discussion Interventions aimed at reducing exposure of Indigenous children to ETS have the potential for significant benefits for Indigenous communities. There is currently a dearth of evidence for the effect of tobacco control interventions to reduce children's exposure to ETS among Indigenous populations. This study will provide high-quality evidence of the efficacy of a family-centred tobacco control program on ETS to reduce respiratory illness. Outcomes of

  9. Splinting after contracture release for Dupuytren's contracture (SCoRD: protocol of a pragmatic, multi-centre, randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Chojnowski Adrian J

    2008-04-01

    Full Text Available Abstract Background Splinting as part of the overall post-surgical management of patients after release of Dupuytren's contracture has been widely reported, though there is variation in practice and criteria for using it. The evidence on its effectiveness is sparse, of poor quality and contradictory with studies reporting negative and positive effects. Methods/Design A multi-centre, pragmatic, randomized, controlled trial is being conducted to evaluate the effect of static night splinting for six months on hand function, range of movement, patient satisfaction and recurrence at 1 year after fasciectomy or dermofasciectomy. Using a centrally administered computer randomization system consented patients will be allocated to one of two groups: i splint group who will be given a static splint at approximately 10 to 14 days after surgery to be worn for 6 months at night time only as well as hand therapy; ii non-splint group, who will receive hand therapy only. The primary outcome measure is the patient-reported Disabilities of the Arm, Hand and Shoulder Questionnaire (DASH. Secondary outcomes are total active flexion and extension of fingers, patient satisfaction and recurrence of contracture. Outcome measures will be collected prior to surgery, 3 months, 6 months and 1 year after surgery. Using the DASH as the primary outcome measure, where a difference of 15 points is considered to be a clinically important difference a total of 51 patients will be needed in each group for a power of 90%. An intention-to-treat analysis will be used. Discussion This pragmatic randomized controlled trial will provide much needed evidence on the clinical effectiveness of post-operative night splinting in patients who have undergone fasciectomy or dermofasciectomy for Dupuytren's contracture of the hand. Trial Registration Current Controlled Trials ISRCTN 57079614

  10. Screening report : Municipality of Leamington : Leamington Pollution Control Centre stand-by emergency power class environmental assessment

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-03-15

    The Leamington Pollution Control Centre (PCC) is located in Ontario and treats residential and commercial wastewater collected from the Municipality of Leamington. The Leamington PCC currently has one standby diesel generator with a rated capacity of 545 kW. This generator provides power to the plant's disinfection facilities to reduce the risk of back-up into the collection system during power failures. The Municipality of Leamington plans to provide treatment in addition to disinfection during power outages. In order to achieve this, additional standby power is required to run the primary clarifiers, the aeration system and the secondary clarifiers. This document presented a screening report for the new standby generator, whose installation is considered a Schedule B under the Municipal Class Environmental Assessment process. The report reviewed background information on the proposed project; Ontario's Environmental Assessment Act; and the Class Environmental Assessment Act. It outlined the problem statement; identification of solutions; existing conditions; impacts and mitigation during construction and operation; and public consultation procedures. 2 refs., 4 figs., 1 appendix.

  11. Use of platelet rich plasma to treat plantar fasciitis: design of a multi centre randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Peerbooms Joost C

    2010-04-01

    Full Text Available Abstract Background If conservative treatment for chronic plantar fasciitis fails, often a corticosteroid injection is given. Corticosteroid injection gives temporarily pain reduction, but no healing. Blood platelets initiate the natural healing rate. GPS® gives an eightfold concentrate platelets of patients own blood. Injection of these platelets in the attachment of the fascia to the os calcis might induce a healing rate. Methods and design A randomized controlled multi centre trial will be performed. The study population consists of 120 patients of 18 years and older. Patients with chronic plantar fasciitis will be allocated randomly to have a steroid injection or an autologous platelet concentrate injections. Data will be collected before the procedure, 4,8,12,26 weeks and 1 year after the procedure. The main outcome measures of this study are pain and function measured with questionnaires. Conclusion Recent literature show positive effects for the treatment of tendinosis with autologous platelet injections. The forthcoming trial will compare treatment for chronic plantar fasciitis with a steroid injection versus an autologous platelet injection. Our results will be published as soon as they become available. Trial Registration Trial registration number: http://www.clinicaltrials.gov NCT00758641.

  12. Psychological and psychosocial functioning of children with burn scarring using cosmetic camouflage: a multi-centre prospective randomised controlled trial.

    Science.gov (United States)

    Maskell, Jessica; Newcombe, Peter; Martin, Graham; Kimble, Roy

    2014-02-01

    Burns leave patients with long-term physical scarring. Children with scarring are required to face challenges of reintegration into their community, including acceptance of an altered appearance and acceptance by others. This can be difficult given society's preoccupation with physical appearance. Limited research exists investigating validity of cosmetic camouflage as a psychosocial intervention for children with scarring. This study investigated whether using cosmetic camouflage (Microskin™) had a positive impact on health-related quality of life, self-concept and psychopathology for children and adolescents (8-17 years) with burn scarring. A prospective multi-centre randomised controlled trial was conducted across Australian and New Zealand paediatric hospitals. 63 participants (49 females, mean age 12.7 ± 2.1 years) were enrolled. Data points were baseline (Time 1) and at 8 weeks (Time 2) using reliable and valid psychometric measures. Findings indicate there were significant improvements in socialisation, school and appearance scales on the Paediatric Quality of Life Inventory and psychopathology scores particularly peer problems decreased. However self-concept remained stable from baseline throughout intervention use. Cosmetic camouflage appears to have a positive impact on quality of life particularly socialisation. Cosmetic camouflage is a valid tool to assist children with scarring to actively participate socially within their communities. Copyright © 2013 Elsevier Ltd and ISBI. All rights reserved.

  13. Procedures for the accounting and control of nuclear materials in large research centres, as related to the needs of international safeguards

    International Nuclear Information System (INIS)

    Kotte, U.; Bueker, H.; Stein, G.

    1976-07-01

    In signatory states of the Non-Proliferation Treaty nuclear material is subject to the supervision of the International Atomic Energy Agency. The IAEA safeguards concept intended for nuclear material has, so far, been predominantly applied to nuclear facilities of the nuclear fuel cycle. It is the aim of this report to consider the applicability of these control measures to a nuclear research centre. The report refers to the concrete example of the Juelich Nuclear Research Centre (KFA). The particular features of a nuclear research centre and the handling of nuclear material in the KFA are described. A review is given of the various licence areas and permitted handling quantities as well as of the inventories and flow of nuclear material. The concept of a control system for a nuclear research centre satisfying the operator's requirements, national requirement and international obligations at the same time is developed along these lines. The essential characteristic of the concept is a far-reaching clarity of the distribution of nuclear material items within the Nuclear Research Centre. The clarity desired will be achieved by means of an integrated accountancy system processing all necessary data with the aid of a central computer and remote terminals. The availability of information is based on differentiated material acountancy in conjunction with adequate measurement of nuclear material data. In the case of the KFA two groups are formed by research reactors and critical assemblies. Research institutes and central departments the permitted handling quantities of which do not exceed 5 eff.kg constitute a further group. Two further groups are formed for cases where the permitted handling quantities are above or below 1 eff.kg. The report shows the safeguards measures that can be applied in certain circumstances and conditions in a nuclear research centre

  14. Six-month exercise training program to treat post-thrombotic syndrome: a randomized controlled two-centre trial

    Science.gov (United States)

    Kahn, Susan R.; Shrier, Ian; Shapiro, Stan; Houweling, Adrielle H.; Hirsch, Andrew M.; Reid, Robert D.; Kearon, Clive; Rabhi, Khalil; Rodger, Marc A.; Kovacs, Michael J.; Anderson, David R.; Wells, Philip S.

    2011-01-01

    Background Exercise training may have the potential to improve post-thrombotic syndrome, a frequent, chronic complication of deep venous thrombosis. We conducted a randomized controlled two-centre pilot trial to assess the feasibility of a multicentre-based evaluation of a six-month exercise training program to treat post-thrombotic syndrome and to obtain preliminary data on the effectiveness of such a program. Methods Patients were randomized to receive exercise training (a six-month trainer-supervised program) or control treatment (an education session with monthly phone follow-ups). Levels of eligibility, consent, adherence and retention were used as indicators of study feasibility. Primary outcomes were change from baseline to six months in venous disease-specific quality of life (as measured using the Venous Insufficiency Epidemiological and Economic Study Quality of Life [VEINES-QOL] questionnaire) and severity of post-thrombotic syndrome (as measured by scores on the Villalta scale) in the exercise training group versus the control group, assessed by t tests. Secondary outcomes were change in generic quality of life (as measured using the Short-Form Health Survey-36 [SF-36] questionnaire), category of severity of post-thrombotic syndrome, leg strength, leg flexibility and time on treadmill. Results Of 95 patients with post-thrombotic syndrome, 69 were eligible, 43 consented and were randomized, and 39 completed the study. Exercise training was associated with improvement in VEINES-QOL scores (exercise training mean change 6.0, standard deviation [SD] 5.1 v. control mean change 1.4, SD 7.2; difference 4.6, 95% CI 0.54 to 8.7; p = 0.027) and improvement in scores on the Villalta scale (exercise training mean change −3.6, SD 3.7 v. control mean change −1.6, SD 4.3; difference −2.0, 95% CI −4.6 to 0.6; p = 0.14). Most secondary outcomes also showed greater improvement in the exercise training group. Interpretation Exercise training may improve post

  15. Understanding satellite-based monthly-to-seasonal reservoir outflow estimation as a function of hydrologic controls

    Science.gov (United States)

    Bonnema, Matthew; Sikder, Safat; Miao, Yabin; Chen, Xiaodong; Hossain, Faisal; Ara Pervin, Ismat; Mahbubur Rahman, S. M.; Lee, Hyongki

    2016-05-01

    Growing population and increased demand for water is causing an increase in dam and reservoir construction in developing nations. When rivers cross international boundaries, the downstream stakeholders often have little knowledge of upstream reservoir operation practices. Satellite remote sensing in the form of radar altimetry and multisensor precipitation products can be used as a practical way to provide downstream stakeholders with the fundamentally elusive upstream information on reservoir outflow needed to make important and proactive water management decisions. This study uses a mass balance approach of three hydrologic controls to estimate reservoir outflow from satellite data at monthly and annual time scales: precipitation-induced inflow, evaporation, and reservoir storage change. Furthermore, this study explores the importance of each of these hydrologic controls to the accuracy of outflow estimation. The hydrologic controls found to be unimportant could potentially be neglected from similar future studies. Two reservoirs were examined in contrasting regions of the world, the Hungry Horse Reservoir in a mountainous region in northwest U.S. and the Kaptai Reservoir in a low-lying, forested region of Bangladesh. It was found that this mass balance method estimated the annual outflow of both reservoirs with reasonable skill. The estimation of monthly outflow from both reservoirs was however less accurate. The Kaptai basin exhibited a shift in basin behavior resulting in variable accuracy across the 9 year study period. Monthly outflow estimation from Hungry Horse Reservoir was compounded by snow accumulation and melt processes, reflected by relatively low accuracy in summer and fall, when snow processes control runoff. Furthermore, it was found that the important hydrologic controls for reservoir outflow estimation at the monthly time scale differs between the two reservoirs, with precipitation-induced inflow being the most important control for the Kaptai

  16. A multi-centre randomised controlled trial of rehabilitation aimed at improving outdoor mobility for people after stroke: Study protocol for a randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Logan Pip A

    2012-06-01

    Full Text Available Abstract Background Up to 42% of all stroke patients do not get out of the house as much as they would like. This can impede a person’s quality of life. This study is testing the clinical effectiveness and cost effectiveness of a new outdoor mobility rehabilitation intervention by comparing it to usual care. Methods/design This is a multi-centre parallel group individually randomised, controlled trial. At least 506 participants will be recruited through 15 primary and secondary care settings and will be eligible if they are over 18 years of age, have had a stroke and wish to get out of the house more often. Participants are being randomly allocated to either the intervention group or the control group. Intervention group participants receive up to 12 rehabilitation outdoor mobility sessions over up to four months. The main component of the intervention is repeated practice of outdoor mobility with a therapist. Control group participants are receiving the usual intervention for outdoor mobility limitations: verbal advice and provision of leaflets provided over one session. Outcome measures are being collected using postal questionnaires, travel calendars and by independent assessors. The primary outcome measure is the Social Function domain of the SF36v2 quality of life assessment six months after recruitment. The secondary outcome measures include: functional ability, mobility, the number of journeys (monthly travel diaries, satisfaction with outdoor mobility, mood, health-related quality of life, resource use of health and social care. Carer mood information is also being collected. The mean Social Function score of the SF-36v2 will be compared between treatment arms using a multiple membership form of mixed effects multiple regression analysis adjusting for centre (as a fixed effect, age and baseline Social Function score as covariates and therapist as a multiple membership random effect. Regression coefficients and 95% confidence

  17. Integrated Power and Attitude Control Design of Satellites Based on a Fuzzy Adaptive Disturbance Observer Using Variable-Speed Control Moment Gyros

    Directory of Open Access Journals (Sweden)

    Zhongyi Chu

    2016-01-01

    Full Text Available To satisfy the requirements for small satellites that seek agile slewing with peak power, this paper investigates integrated power and attitude control using variable-speed control moment gyros (VSCMGs that consider the mass and inertia of gimbals and wheels. The paper also details the process for developing the controller by considering various environments in which the controller may be implemented. A fuzzy adaptive disturbance observer (FADO is proposed to estimate and compensate for the effects of equivalent disturbances. The algorithms can simultaneously track attitude and power. The simulation results illustrate the effectiveness of the control approach, which exhibits an improvement of 80 percent compared with alternate approaches that do not employ a FADO.

  18. HIV and childhood disability: a case-controlled study at a paediatric antiretroviral therapy centre in Lilongwe, Malawi.

    Science.gov (United States)

    Devendra, Akash; Makawa, Atupele; Kazembe, Peter N; Calles, Nancy R; Kuper, Hannah

    2013-01-01

    As paediatric antiretroviral therapy (ART) is rapidly scaled up in Southern Africa, Human Immunodeficiency Virus (HIV) infection is becoming a chronic illness. Children growing up with HIV may begin to encounter disabilities. The relationship between HIV, disability and the need for rehabilitation has added an additional element that needs to be addressed by paediatric HIV treatment programmes. 1) Estimate the prevalence of disabilities in HIV-infected and HIV-uninfected children in Lilongwe, Malawi. 2) Examine types of disability and associated clinical and socio-demographic factors. 3) Identify needs, opportunities and barriers for rehabilitation in Malawi. A case-controlled study of 296 HIV-infected children aged 2-9 years attending an ART centre in Lilongwe (cases) and their uninfected siblings (controls) was conducted. Disability was assessed using the WHO Ten Question Screen (TQS). Socio-demographic and clinical data were collected using a parent-proxy questionnaire and medical records. Of 296 case and control pairs recruited, 33% (98) versus 7% (20) screened positive for a disability (OR 8.4, 4.4-15.7) respectively. Of these 98 HIV-infected cases, 6%, 36%, 33%, 53%, 46% and 6% had a vision, hearing; physical, learning/comprehension, speech or seizure-related disability respectively and 51% had multiple coexisting disabilities. HIV-infected cases with a disability were more likely to be WHO stage III or IV at enrolment (71% vs. 52%, OR 2.7, 1.5-4.2), to have had TB (58% vs. 39%, OR 2.3, 1.4-3.8) and to have below-average school grades (18% vs. 2%, OR 11.1, 2.2-54.6) than those without. Sixty-seven percent of cases with a disability had never attended any rehabilitative service. Twenty-nine percent of caregivers reported facing stigma and discrimination because of the child's disability. This study reveals the magnitude of disability among HIV-infected children and the large unmet need for rehabilitation services. This expanding issue demands further

  19. HIV and childhood disability: a case-controlled study at a paediatric antiretroviral therapy centre in Lilongwe, Malawi.

    Directory of Open Access Journals (Sweden)

    Akash Devendra

    Full Text Available BACKGROUND: As paediatric antiretroviral therapy (ART is rapidly scaled up in Southern Africa, Human Immunodeficiency Virus (HIV infection is becoming a chronic illness. Children growing up with HIV may begin to encounter disabilities. The relationship between HIV, disability and the need for rehabilitation has added an additional element that needs to be addressed by paediatric HIV treatment programmes. STUDY OBJECTIVES: 1 Estimate the prevalence of disabilities in HIV-infected and HIV-uninfected children in Lilongwe, Malawi. 2 Examine types of disability and associated clinical and socio-demographic factors. 3 Identify needs, opportunities and barriers for rehabilitation in Malawi. METHODS: A case-controlled study of 296 HIV-infected children aged 2-9 years attending an ART centre in Lilongwe (cases and their uninfected siblings (controls was conducted. Disability was assessed using the WHO Ten Question Screen (TQS. Socio-demographic and clinical data were collected using a parent-proxy questionnaire and medical records. RESULTS: Of 296 case and control pairs recruited, 33% (98 versus 7% (20 screened positive for a disability (OR 8.4, 4.4-15.7 respectively. Of these 98 HIV-infected cases, 6%, 36%, 33%, 53%, 46% and 6% had a vision, hearing; physical, learning/comprehension, speech or seizure-related disability respectively and 51% had multiple coexisting disabilities. HIV-infected cases with a disability were more likely to be WHO stage III or IV at enrolment (71% vs. 52%, OR 2.7, 1.5-4.2, to have had TB (58% vs. 39%, OR 2.3, 1.4-3.8 and to have below-average school grades (18% vs. 2%, OR 11.1, 2.2-54.6 than those without. Sixty-seven percent of cases with a disability had never attended any rehabilitative service. Twenty-nine percent of caregivers reported facing stigma and discrimination because of the child's disability. CONCLUSION: This study reveals the magnitude of disability among HIV-infected children and the large unmet need for

  20. Short video interventions to reduce mental health stigma: a multi-centre randomised controlled trial in nursing high schools.

    Science.gov (United States)

    Winkler, Petr; Janoušková, Miroslava; Kožený, Jiří; Pasz, Jiří; Mladá, Karolína; Weissová, Aneta; Tušková, Eva; Evans-Lacko, Sara

    2017-12-01

    We aimed to assess whether short video interventions could reduce stigma among nursing students. A multi-centre, randomised controlled trial was conducted. Participating schools were randomly selected and randomly assigned to receive: (1) an informational leaflet, (2) a short video intervention or (3) a seminar involving direct contact with a service user. The Community Attitudes towards Mental Illness (CAMI) and Reported and Intended Behaviour Scale (RIBS) were selected as primary outcome measures. SPANOVA models were built and Cohen's d calculated to assess the overall effects in each of the trial arms. Compared to the baseline, effect sizes immediately after the intervention were small in the flyer arm (CAMI: d = 0.25; RIBS: d = 0.07), medium in the seminar arm (CAMI: d = 0.61; RIBS: d = 0.58), and medium in the video arm (CAMI: d = 0.49 RIBS: d = 0.26; n = 237). Effect sizes at the follow-up were vanishing in the flyer arm (CAMI: d = 0.05; RIBS: d = 0.04), medium in the seminar arm (CAMI: d = 0.43; RIBS: d = 0.26; n = 254), and small in the video arm (CAMI: d = 0.22 RIBS: d = 0.21; n = 237). Seminar had the strongest and relatively stable effect on students' attitudes and intended behaviour, but the effect of short video interventions was also considerable and stable over time. Since short effective video interventions are relatively cheap, conveniently accessible and easy to disseminate globally, we recommend them for further research and development.

  1. Assessment for Operator Confidence in Automated Space Situational Awareness and Satellite Control Systems

    Science.gov (United States)

    Gorman, J.; Voshell, M.; Sliva, A.

    2016-09-01

    The United States is highly dependent on space resources to support military, government, commercial, and research activities. Satellites operate at great distances, observation capacity is limited, and operator actions and observations can be significantly delayed. Safe operations require support systems that provide situational understanding, enhance decision making, and facilitate collaboration between human operators and system automation both in-the-loop, and on-the-loop. Joint cognitive systems engineering (JCSE) provides a rich set of methods for analyzing and informing the design of complex systems that include both human decision-makers and autonomous elements as coordinating teammates. While, JCSE-based systems can enhance a system analysts' understanding of both existing and new system processes, JCSE activities typically occur outside of traditional systems engineering (SE) methods, providing sparse guidance about how systems should be implemented. In contrast, the Joint Director's Laboratory (JDL) information fusion model and extensions, such as the Dual Node Network (DNN) technical architecture, provide the means to divide and conquer such engineering and implementation complexity, but are loosely coupled to specialized organizational contexts and needs. We previously describe how Dual Node Decision Wheels (DNDW) extend the DNN to integrate JCSE analysis and design with the practicalities of system engineering and implementation using the DNN. Insights from Rasmussen's JCSE Decision Ladders align system implementation with organizational structures and processes. In the current work, we present a novel approach to assessing system performance based on patterns occurring in operational decisions that are documented by JCSE processes as traces in a decision ladder. In this way, system assessment is closely tied not just to system design, but the design of the joint cognitive system that includes human operators, decision-makers, information systems, and

  2. Effects and meanings of a person-centred and health-promoting intervention in home care services - a study protocol of a non-randomised controlled trial.

    Science.gov (United States)

    Bölenius, Karin; Lämås, Kristina; Sandman, Per-Olof; Edvardsson, David

    2017-02-16

    The literature indicates that current home care service are largely task oriented with limited focus on the involvement of the older people themselves, and studies show that lack of involvement might reduce older people's quality of life. Person-centred care has been shown to improve the satisfaction with care and quality of life in older people cared for in hospitals and nursing homes, with limited published evidence about the effects and meanings of person-centred interventions in home care services for older people. This study protocol outlines a study aiming to evaluate such effects and meanings of a person-centred and health-promoting intervention in home aged care services. The study will take the form of a non-randomised controlled trial with a before/after approach. It will include 270 older people >65 years receiving home care services, 270 relatives and 65 staff, as well as a matched control group of equal size. All participants will be recruited from a municipality in northern Sweden. The intervention is based on the theoretical concepts of person-centredness and health-promotion, and builds on the four pedagogical phases of: theory apprehension, experimental learning, operationalization, and clinical supervision. Outcome assessments will focus on: a) health and quality of life (primary outcomes), thriving and satisfaction with care for older people; b) caregiver strain, informal caregiving engagement and relatives' satisfaction with care: c) job satisfaction and stress of conscience among care staff (secondary outcomes). Evaluation will be conducted by means of self-reported questionnaires and qualitative research interviews. Person-centred home care services have the potential to improve the recurrently reported sub-standard experiences of home care services, and the results can point the way to establishing a more person-centred and health-promoting model for home care services for older people. NCT02846246 .

  3. Efficiency of piezosurgery technique in miniscrew supported en-masse retraction: a single-centre, randomized controlled trial.

    Science.gov (United States)

    Tunçer, Nilüfer Irem; Arman-Özçirpici, Ayça; Oduncuoglu, Bahar Füsun; Göçmen, Jülide Sedef; Kantarci, Alpdogan

    2017-11-30

    Piezoelectric surgery is a newly introduced technique for rapid tooth movement. However, the efficiency of this technique has not been investigated on en-masse retraction cases yet. To investigate the efficiency of piezosurgery technique in accelerating miniscrew supported en-masse retraction and study the biological tissue response. In addition, to show if this technique induces a difference in dental, skeletal and soft tissue changes on lateral cephalograms, and in canine and molar rotations, besides intercanine and intermolar widths on dental casts. We conducted a randomized, single-centred, parallel-group, controlled trial, requiring upper right and left first premolar extractions on 30 patients above the minimum age of 14 years at the beginning of retraction. Piezosurgery-assisted versus conventional en-masse retraction anchored from miniscrews placed between second premolars and first molars, bilaterally. The main outcome was the en-masse retraction rate. Secondary outcomes were gingival crevicular fluid (GCF) volume and GCF content of receptor activator of nuclear factor κβ ligand (RANKL), changes regarding cephalometric and dental cast variables, and miniscrew success rates. Accomplished with opaque, sealed envelopes. Applicable for data assessment only. Commenced in February 2013 and ended in October 2014. Thirty-one patients were included in the study and divided into 2 groups of piezosurgery (n = 16) and control (n = 15). After 9.3 months of follow-up, no statistically significant difference was observed between groups for neither retraction rates (P = 0.958) nor GCF parameters (P > 0.05). Changes in lateral cephalometric and dental cast variables, and miniscrew success rates did not show significant differences either. Based on the results of this study, piezosurgery technique was found to be ineffective in accelerating en-masse retraction, and promoting a difference in the studied GCF parameters, skeletal and dental variables. The trial was not

  4. Efficacy and safety of acupuncture for chronic pain caused by gonarthrosis: A study protocol of an ongoing multi-centre randomised controlled clinical trial [ISRCTN27450856

    Directory of Open Access Journals (Sweden)

    Krämer Jürgen

    2004-03-01

    Full Text Available Abstract Background Controlled clinical trials produced contradictory results with respect to a specific analgesic effect of acupuncture. There is a lack of large multi-centre acupuncture trials. The German Acupuncture Trial represents the largest multi-centre study of acupuncture in the treatment of chronic pain caused by gonarthrosis up to now. Methods 900 patients will be randomised to three treatment arms. One group receives verum acupuncture, the second sham acupuncture, and the third conservative standard therapy. The trial protocol is described with eligibility criteria, detailed information on the treatment definition, blinding, endpoints, safety evaluation, statistical methods, sample size determination, monitoring, legal aspects, and the current status of the trial. Discussion A critical discussion is given regarding the considerations about standardisation of the acupuncture treatment, the choice of the control group, and the blinding of patients and observers.

  5. Development of an advanced mechanised gait trainer, controlling movement of the centre of mass, for restoring gait in non-ambulant subjects.

    Science.gov (United States)

    Hesse, S; Sarkodie-Gyan, T; Uhlenbrock, D

    1999-01-01

    The study aimed at further development of a mechanised gait trainer which would allow non-ambulant people to practice a gait-like motion repeatedly. To simulate normal gait, discrete stance and swing phases, lasting 60% and 40% of the gait cycle respectively, and the control of the movement of the centre of mass were required. A complex gear system provided the gait-like movement of two foot plates with a ratio of 60% to 40% between the stance and swing phases. A controlled propulsion system adjusted its output according to patient's efforts. Two eccenters on the central gear controlled phase-adjusted the vertical and horizontal position of the centre of mass. The patterns of sagittal lower limb joint kinematics and of muscle activation of a normal subject were similar when using the mechanised trainer and when walking on a treadmill. A non-ambulatory hemiparetic subject required little help from one therapist on the gait trainer, while two therapists supported treadmill walking. Gait movements on the trainer were highly symmetrical, impact-free, and less spastic. The weight-bearing muscles were activated in a similar fashion during both conditions. The vertical displacement of the centre of mass was bi-instead of mono-phasic during each gait cycle on the new device. In conclusion, the gait trainer allowed wheelchair-bound subjects the repetitive practice of a gait-like movement without overstraining therapists.

  6. Satellite assisted aerosol correlation in a sequestered CO2 leakage controlled site

    Science.gov (United States)

    Landulfo, Eduardo; da Silva Lopes, Fábio J.; Nakaema, Walter M.; de Medeiros, José A. G.; Moreira, Andrea

    2014-10-01

    Currently one of the main challenges in CO2 storage research is to grant the development, testing and validation of accurate and efficient Measuring, Monitoring and Verification (MMV) techniques to be deployed at the final storage site, targeting maximum storage efficiency at the minimal leakage risk levels. For such task a mimetic sequestration site has been deployed in Florianopolis, Brazil, in order to verify the performance of monitoring plataforms to detect and quantify leakages of ground injected CO2, namely a Cavity Ring Down System (CRDS) - Los Gatos Research - an Eddy Covariance System (Campbell Scientific and Irgason) and meteorological tower for wind, humidity, precipitation and temperature monitoring onsite. The measurement strategy for detecting CO2 leakages can be very challenging since environmental and phytogenic influence can be very severe and play a role on determining if the values measured are unambiguous or not. One external factor to be considered is the amount of incoming solar radiation which will be the driving force for the whole experimental setup and following this reasoning the amount of aerosols in the atmospheric column can be a determinant factor influencing the experimental results. Thus the investigation of measured fluxes CO2 and its concentration with the aforementioned experimental instruments and their correlation with the aerosol data should be taken into account by means of satellite borne systems dedicated to measure aerosol vertical distribution and its optical properties, in this study we have selected CALIPSO and MODIS instrumentation to help on deriving the aerosol properties and CO2 measurements.

  7. A data-driven approach to identify controls on global fire activity from satellite and climate observations (SOFIA V1

    Directory of Open Access Journals (Sweden)

    M. Forkel

    2017-12-01

    Full Text Available Vegetation fires affect human infrastructures, ecosystems, global vegetation distribution, and atmospheric composition. However, the climatic, environmental, and socioeconomic factors that control global fire activity in vegetation are only poorly understood, and in various complexities and formulations are represented in global process-oriented vegetation-fire models. Data-driven model approaches such as machine learning algorithms have successfully been used to identify and better understand controlling factors for fire activity. However, such machine learning models cannot be easily adapted or even implemented within process-oriented global vegetation-fire models. To overcome this gap between machine learning-based approaches and process-oriented global fire models, we introduce a new flexible data-driven fire modelling approach here (Satellite Observations to predict FIre Activity, SOFIA approach version 1. SOFIA models can use several predictor variables and functional relationships to estimate burned area that can be easily adapted with more complex process-oriented vegetation-fire models. We created an ensemble of SOFIA models to test the importance of several predictor variables. SOFIA models result in the highest performance in predicting burned area if they account for a direct restriction of fire activity under wet conditions and if they include a land cover-dependent restriction or allowance of fire activity by vegetation density and biomass. The use of vegetation optical depth data from microwave satellite observations, a proxy for vegetation biomass and water content, reaches higher model performance than commonly used vegetation variables from optical sensors. We further analyse spatial patterns of the sensitivity between anthropogenic, climate, and vegetation predictor variables and burned area. We finally discuss how multiple observational datasets on climate, hydrological, vegetation, and socioeconomic variables together with

  8. A data-driven approach to identify controls on global fire activity from satellite and climate observations (SOFIA V1)

    Science.gov (United States)

    Forkel, Matthias; Dorigo, Wouter; Lasslop, Gitta; Teubner, Irene; Chuvieco, Emilio; Thonicke, Kirsten

    2017-12-01

    Vegetation fires affect human infrastructures, ecosystems, global vegetation distribution, and atmospheric composition. However, the climatic, environmental, and socioeconomic factors that control global fire activity in vegetation are only poorly understood, and in various complexities and formulations are represented in global process-oriented vegetation-fire models. Data-driven model approaches such as machine learning algorithms have successfully been used to identify and better understand controlling factors for fire activity. However, such machine learning models cannot be easily adapted or even implemented within process-oriented global vegetation-fire models. To overcome this gap between machine learning-based approaches and process-oriented global fire models, we introduce a new flexible data-driven fire modelling approach here (Satellite Observations to predict FIre Activity, SOFIA approach version 1). SOFIA models can use several predictor variables and functional relationships to estimate burned area that can be easily adapted with more complex process-oriented vegetation-fire models. We created an ensemble of SOFIA models to test the importance of several predictor variables. SOFIA models result in the highest performance in predicting burned area if they account for a direct restriction of fire activity under wet conditions and if they include a land cover-dependent restriction or allowance of fire activity by vegetation density and biomass. The use of vegetation optical depth data from microwave satellite observations, a proxy for vegetation biomass and water content, reaches higher model performance than commonly used vegetation variables from optical sensors. We further analyse spatial patterns of the sensitivity between anthropogenic, climate, and vegetation predictor variables and burned area. We finally discuss how multiple observational datasets on climate, hydrological, vegetation, and socioeconomic variables together with data

  9. Wavelet Transform Analysis of the Power Spectrum of Centre of Pressure Signals to Detect the Critical Point Interval of Postural Control

    Science.gov (United States)

    Singh, Neeraj Kumar; Snoussi, Hichem; Hewson, David; Duchêne, Jacques

    The aim of this study was to develop a method to detecting the critical point interval (CPI) when sensory feedback is used as part of a closed-loop postural control strategy. Postural balance was evaluated using centre of pressure (COP) displacements from a force plate for 17 control and 10 elderly subjects under eyes open, eyes closed, and vibration conditions. A modified local-maximum-modulus wavelet transform analysis using the power spectrum of COP signals was used to calculate CPI. Lower CPI values indicate increased closed-loop postural control with a quicker response to sensory input. Such a strategy requires greater energy expenditure due to the repeated muscular interventions to remain stable. The CPI for elderly occurred significantly quicker than for controls, indicating tighter control of posture. Similar results were observed for eyes closed and vibration conditions. The CPI parameter can be used to detect differences in postural control due to ageing.

  10. Satellite view of seasonal greenness trends and controls in South Asia

    Science.gov (United States)

    Sarmah, Sangeeta; Jia, Gensuo; Zhang, Anzhi

    2018-03-01

    South Asia (SA) has been considered one of the most remarkable regions for changing vegetation greenness, accompanying its major expansion of agricultural activities, especially irrigated farming. The influence of the monsoon climate on the seasonal trends and anomalies of vegetation greenness is poorly understood in this area. Herein, we used the satellite-based Normalized Difference Vegetation Index (NDVI) to investigate various spatiotemporal patterns in vegetation activity during summer and winter monsoon (SM and WM) seasons and among irrigated croplands (IC), rainfed croplands (RC), and natural vegetation (NV) areas during 1982–2013. Seasonal NDVI variations with climatic factors (precipitation and temperature) and land use and cover changes (LUCC) have also been investigated. This study demonstrates that the seasonal dynamics of vegetation could improve the detailed understanding of vegetation productivity over the region. We found distinct greenness trends between two monsoon seasons and among the major land use/cover classes. Winter monsoons contributed greater variability to the overall vegetation dynamics of SA. Major greening occurred due to the increased productivity over irrigated croplands during the winter monsoon season; meanwhile, browning trends were prominent over NV areas during the same season. Maximum temperatures had been increasing tremendously during the WM season; however, the precipitation trend was not significant over SA. Both the climate variability and LUCC revealed coupled effects on the long term NDVI trends in NV areas, especially in the hilly regions, whereas anthropogenic activities (agricultural advancements) played a pivotal role in the rest of the area. Until now, advanced cultivation techniques have proven to be beneficial for the region in terms of the productivity of croplands. However, the crop productivity is at risk under climate change.

  11. Feasibility and Preliminary Efficacy of Visual Cue Training to Improve Adaptability of Walking after Stroke: Multi-Centre, Single-Blind Randomised Control Pilot Trial

    Science.gov (United States)

    Hollands, Kristen L.; Pelton, Trudy A.; Wimperis, Andrew; Whitham, Diane; Tan, Wei; Jowett, Sue; Sackley, Catherine M.; Wing, Alan M.; Tyson, Sarah F.; Mathias, Jonathan; Hensman, Marianne; van Vliet, Paulette M.

    2015-01-01

    Objectives Given the importance of vision in the control of walking and evidence indicating varied practice of walking improves mobility outcomes, this study sought to examine the feasibility and preliminary efficacy of varied walking practice in response to visual cues, for the rehabilitation of walking following stroke. Design This 3 arm parallel, multi-centre, assessor blind, randomised control trial was conducted within outpatient neurorehabilitation services Participants Community dwelling stroke survivors with walking speed adaptability practice using visual cues are feasible and may improve mobility and balance. Future studies should continue a carefully phased approach using identified methods to improve retention. Trial Registration Clinicaltrials.gov NCT01600391 PMID:26445137

  12. KWARTA (Quality Assurance in the Radiotherapy centres of the Antwerp province): Quality control of the contract therapy machine and treatment planning system

    Energy Technology Data Exchange (ETDEWEB)

    De Ost, B; Schaeken, B; Vanregemorter, J [Algemeen Ziekenhuis Middelheim, Antwerp (Belgium); Bellekens, L [Sint-Vincentius Ziekenhuis, Antwerp (Belgium); Cardoen, R; Pieters, D [Medisch Instituut Sint Augustinus, Wilrijk (Belgium); Goossens, H [Sint-Elisabeth Ziekenhuis, Turnhout (Belgium); Haest, K; Mertens, N [Sint Norbertus Ziekenhuis, Duffel (Belgium)

    1995-12-01

    During the first year of the provincial QA project, joint procedures were set up for the routine quality control of linear accelerators, Cobalt treatment machines and simulators. A set of standard forms was produced for use in all centres, respecting the differences in each individual machine. Since forms are now in use in all centres, the second year of the project mainly focused on the QA/QC of the contract therapy machine and treatment planning system. QC measurements for the contract therapy machines were performed in air or in a phantom. Since the output was checked with the same ionisation chamber (0.33 cc flat chamber calibrated for 50 kV) and the same type of electrometer in all centres, the results could be compared mutually and with the reference values. The major parameter groups, tested for the treatment planning system were: isodose distribution (visual control of all square fields in the database of the system), PDD data (analysing of 10 x 10 cm{sup 2}, 20 x 20 cm{sup 2}, 30 x 30 cm{sup 2} and 40 x 40 cm{sup 2} open or wedged fields), output factors, wedge and tray factors, inverse square law, geometrical testing of the digitizer - screen - printer and geometrical and densitometrical testing of the CT images - screen - printer. Between 496 and 1243 parameters were investigated in the different centres (depending on the presence of the electron data). Irregularities (0 % to 4 % of the total investigated parameters) were reported to the respective physicist.

  13. Understanding the Seasonal Greenness Trends and Controls in South Asia Using Satellite Based Observations

    Science.gov (United States)

    Sarmah, S.; Jia, G.; Zhang, A.; Singha, M.

    2017-12-01

    South Asia (SA) is one of the most remarkable regions in changing vegetation greenness along with its major expansion of agricultural activity, especially irrigated farming. However, SA is predicted to be a vulnerable agricultural regions to future climate changes. The influence of monsoon climate on the seasonal trends and anomalies of vegetation greenness are not well understood in the region which can provide valuable information about climate-ecosystem interaction. This study analyzed the spatio-temporal patterns of seasonal vegetation trends and variability using satellite vegetation indices (VI) including AVHRR Normalized Difference Vegetation Index (NDVI) (1982-2013) and MODIS Enhanced Vegetation Index (EVI) (2000-2013) in summer monsoon (SM) (June-Sept) and winter monsoon (WM) (Dec-Apr) seasons among irrigated cropland (IC), rainfed cropland (RC) and natural vegetation (NV). Seasonal VI variations with climatic factors (precipitation and temperature) and LULC changes have been investigated to identify the forcings behind the vegetation trends and variability. We found that major greening occurred in the last three decades due to the increase in IC productivity noticeably in WM, however, recent (2000-2013) greening trends were lower than the previous decades (1982-1999) in both the IC and RC indicating the stresses on them. The browning trends, mainly concentrated in NV areas were prominent during WM and rigorous since 2000, confirmed from the moderate resolution EVI and LULC datasets. Winter time maximal temperature had been increasing tremendously whereas precipitation trend was not significant over SA. Both the climate variability and LULC changes had integrated effects on the vegetation changes in NV areas specifically in hilly regions. However, LULC impact was intensified since 2000, mostly in north east India. This study also revealed a distinct seasonal variation in spatial distribution of correlation between VI's and climate anomalies over SA

  14. High speed reaction wheels for satellite attitude control and energy storage

    Science.gov (United States)

    Studer, P.; Rodriguez, E.

    1985-01-01

    The combination of spacecraft attitude control and energy storage (ACES) functions in common hardware, to synergistically maintain three-axis attitude control while supplying electrical power during earth orbital eclipses, allows the generation of control torques by high rotating speed wheels that react against the spacecraft structure via a high efficiency bidirectional energy conversion motor/generator. An ACES system encompasses a minimum of four wheels, controlling power and the three torque vectors. Attention is given to the realization of such a system with composite flywheel rotors that yield high energy density, magnetic suspension technology yielding low losses at high rotational speeds, and an ironless armature permanent magnet motor/generator yielding high energy conversion efficiency.

  15. Regional Centres for Space Science and Technology Education and ICG Information Centres affiliated to the United Nations

    Science.gov (United States)

    Gadimova, S.; Haubold, H. J.

    2009-06-01

    Based on resolutions of the United Nations General Assembly, Regional Centres for Space Science and Technology Education were established in India, Morocco, Nigeria, Brazil and Mexico. Simultaneously, education curricula were developed for the core disciplines of remote sensing, satellite communications, satellite meteorology, and space and atmospheric science. This paper provides a brief summary on the status of the operation of the regional centres with a view to use them as information centres of the International Committee on Global Navigation Satellite Systems (ICG), and draws attention to their educational activities.

  16. Domestic Communication Satellites

    Science.gov (United States)

    Horowitz, Andrew

    1974-01-01

    A discussion of the Federal Communications Commission's new policy on domestic satellites in light of our 1) military and economic history; 2) corporate interests; 3) citizen surveillance; and 4) media control. (HB)

  17. Saturn satellites

    International Nuclear Information System (INIS)

    Ruskol, E.L.

    1981-01-01

    The characteristics of the Saturn satellites are discussed. The satellites close to Saturn - Janus, Mimas, Enceladus, Tethys, Dione and Rhea - rotate along the circular orbits. High reflectivity is attributed to them, and the density of the satellites is 1 g/cm 3 . Titan is one of the biggest Saturn satellites. Titan has atmosphere many times more powerful than that of Mars. The Titan atmosphere is a peculiar medium with a unique methane and hydrogen distribution in the whole Solar system. The external satellites - Hyperion, Japetus and Phoebe - are poorly investigated. Neither satellite substance density, nor their composition are known. The experimental data on the Saturn rings obtained on the ''Pioneer-11'' and ''Voyager-1'' satellites are presented [ru

  18. Variability in the mechanisms controlling Southern Ocean phytoplankton bloom phenology in an ocean model and satellite observations

    Science.gov (United States)

    Rohr, Tyler; Long, Matthew C.; Kavanaugh, Maria T.; Lindsay, Keith; Doney, Scott C.

    2017-05-01

    A coupled global numerical simulation (conducted with the Community Earth System Model) is used in conjunction with satellite remote sensing observations to examine the role of top-down (grazing pressure) and bottom-up (light, nutrients) controls on marine phytoplankton bloom dynamics in the Southern Ocean. Phytoplankton seasonal phenology is evaluated in the context of the recently proposed "disturbance-recovery" hypothesis relative to more traditional, exclusively "bottom-up" frameworks. All blooms occur when phytoplankton division rates exceed loss rates to permit sustained net population growth; however, the nature of this decoupling period varies regionally in Community Earth System Model. Regional case studies illustrate how unique pathways allow blooms to emerge despite very poor division rates or very strong grazing rates. In the Subantarctic, southeast Pacific small spring blooms initiate early cooccurring with deep mixing and low division rates, consistent with the disturbance-recovery hypothesis. Similar systematics are present in the Subantarctic, southwest Atlantic during the spring but are eclipsed by a subsequent, larger summer bloom that is coincident with shallow mixing and the annual maximum in division rates, consistent with a bottom-up, light limited framework. In the model simulation, increased iron stress prevents a similar summer bloom in the southeast Pacific. In the simulated Antarctic zone (70°S-65°S) seasonal sea ice acts as a dominant phytoplankton-zooplankton decoupling agent, triggering a delayed but substantial bloom as ice recedes. Satellite ocean color remote sensing and ocean physical reanalysis products do not precisely match model-predicted phenology, but observed patterns do indicate regional variability in mechanism across the Atlantic and Pacific.

  19. International Telecommunication Control: International Law and the Ordering of Satellite and Other Forms of International Broadcasting.

    Science.gov (United States)

    Smith, Delbert D.

    The need for and the available alternatives for international telecommunication controls are examined, and a functional approach to this area of law is offered. Information from a number of areas is collected and examined as it relates to the basic problem. These areas include general principles of international law, the activities of the…

  20. 15th March 2011 - Singapore National Research Foundation Permanent Secretary(National Research and Development)T. M. Kian signing the guest book with Head of International Relations F. Pauss and visiting CMS control centre with Collaboration Spokesperson G. Tonelli.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    15th March 2011 - Singapore National Research Foundation Permanent Secretary(National Research and Development)T. M. Kian signing the guest book with Head of International Relations F. Pauss and visiting CMS control centre with Collaboration Spokesperson G. Tonelli.

  1. 7 March 2013 -Stanford University Professor N. McKeown FREng, Electrical Engineering and Computer Science and B. Leslie, Creative Labs visiting CERN Control Centre and the LHC tunnel with Director for Accelerators and Technology S. Myers.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    7 March 2013 -Stanford University Professor N. McKeown FREng, Electrical Engineering and Computer Science and B. Leslie, Creative Labs visiting CERN Control Centre and the LHC tunnel with Director for Accelerators and Technology S. Myers.

  2. Proposal for the award of a contract for the design, supply, installation and commissioning of a Heating, Ventilation and Air-Conditioning (HVAC) system for the computer room of the CERN Control Centre

    CERN Document Server

    2012-01-01

    Proposal for the award of a contract for the design, supply, installation and commissioning of a Heating, Ventilation and Air-Conditioning (HVAC) system for the computer room of the CERN Control Centre

  3. Factors influencing choice of care-seeking for acute fever comparing private chemical shops with health centres and hospitals in Ghana: a study using case-control methodology.

    Science.gov (United States)

    Ansah, Evelyn K; Gyapong, Margaret; Narh-Bana, Solomon; Bart-Plange, Constance; Whitty, Christopher J M

    2016-05-25

    Several public health interventions to improve management of patients with fever are largely focused on the public sector yet a high proportion of patients seek care outside the formal healthcare sector. Few studies have provided information on the determinants of utilization of the private sector as against formal public sector. Understanding the differences between those who attend public and private health institutions, and their pathway to care, has significant practical implications. The chemical shop is an important source of care for acute fever in Ghana. Case-control methodology was used to identify factors associated with seeking care for fever in the Dangme West District, Ghana. People presenting to health centres, or hospital outpatients, with a history or current fever were compared to counterparts from the same community with fever visiting a chemical shop. Of 600 patients, 150 each, were recruited from the district hospital and two health centres, respectively, and 300 controls from 51 chemical shops. Overall, 103 (17.2 %) patients tested slide positive for malaria. Specifically, 13.7 % (41/300) of chemical shop patients, 30.7 % (46/150) health centre and 10.7 % (16/150) hospital patients were slide positive. While it was the first option for care for 92.7 % (278/300) chemical shop patients, 42.7 % (64/150) of health centre patients first sought care from a chemical shop. More health centre patients (61.3 %; 92/150) presented with fever after more than 3 days than chemical shop patients (27.7 %; 83/300) [AOR = 0.19; p private drug retail sector is the first option for the majority of patients, including poorer patients, with fever in this setting. Most patients with fever arrive at chemical shops with less delay and fewer signs of severity than at public health facilities. Improving chemical shop skills is a good opportunity to diagnose, treat or refer people with fever early.

  4. Attitude and vibration control of a satellite containing flexible solar arrays by using reaction wheels, and piezoelectric transducers as sensors and actuators

    Science.gov (United States)

    da Fonseca, Ijar M.; Rade, Domingos A.; Goes, Luiz C. S.; de Paula Sales, Thiago

    2017-10-01

    The primary purpose of this paper is to provide insight into control-structure interaction for satellites comprising flexible appendages and internal moving components. The physical model considered herein aiming to attend such purpose is a rigid-flexible satellite consisting of a rigid platform containing two rotating flexible solar panels. The solar panels rotation is assumed to be in a sun-synchronous configuration mode. The panels contain surface-bonded piezoelectric patches that can be used either as sensors for the elastic displacements or as actuators to counteract the vibration motion. It is assumed that in the normal mode operation the satellite platform points towards the Earth while the solar arrays rotate so as to follow the Sun. The vehicle moves in a low Earth polar orbit. The technique used to obtain the mathematical model combines the Lagrangian formulation with the Finite Elements Method used to describe the dynamics of the solar panel. The gravity-gradient torque as well as the torque due to the interaction of the Earth magnetic field and the satellite internal residual magnetic moment is included as environmental perturbations. The actuators are three reaction wheels for attitude control and piezoelectric actuators to control the flexible motion of the solar arrays. Computer simulations are performed using the MATLAB® software package. The following on-orbit satellite operating configurations are object of analysis: i) Satellite pointing towards the Earth (Earth acquisition maneuver) by considering the initial conditions in the elastic displacement equal to zero, aiming the assessment of the flexible modes excitation by the referred maneuver; ii) the satellite pointing towards the Earth with the assumption of an initial condition different from zero for the flexible motion such that the attitude alterations are checked against the elastic motion disturbance; and iii) attitude acquisition accomplished by taking into account initial conditions

  5. The Arms Control and Crisis Management Potential of the Proposed International Satellite Monitoring Agency (ISMA)

    Science.gov (United States)

    1984-12-01

    unbiased scientific method , is widespread in the West. This is particularly true of the two arms control functions to which an ISMA would contribute...Elizabeth Young (Lord and Lady Kennett), Neitber Red Nor Dead:_ The Case for Dis• aumAmjeif, Social Democratic Party (SDP), Open Forum Paper No. 2...in the national interest. The Soviet Union is not the first, and is unlikely to be the last, country to adopt a . narrow, constructionist approach to

  6. A global network for the control of snail-borne disease using satellite surveillance and geographic information systems.

    Science.gov (United States)

    Malone, J B; Bergquist, N R; Huh, O K; Bavia, M E; Bernardi, M; El Bahy, M M; Fuentes, M V; Kristensen, T K; McCarroll, J C; Yilma, J M; Zhou, X N

    2001-04-27

    At a team residency sponsored by the Rockefeller Foundation in Bellagio, Italy, 10-14 April 2000 an organizational plan was conceived to create a global network of collaborating health workers and earth scientists dedicated to the development of computer-based models that can be used for improved control programs for schistosomiasis and other snail-borne diseases of medical and veterinary importance. The models will be assembled using GIS methods, global climate model data, sensor data from earth observing satellites, disease prevalence data, the distribution and abundance of snail hosts, and digital maps of key environmental factors that affect development and propagation of snail-borne disease agents. A work plan was developed for research collaboration and data sharing, recruitment of new contributing researchers, and means of access of other medical scientists and national control program managers to GIS models that may be used for more effective control of snail-borne disease. Agreement was reached on the use of compatible GIS formats, software, methods and data resources, including the definition of a 'minimum medical database' to enable seamless incorporation of results from each regional GIS project into a global model. The collaboration plan calls for linking a 'central resource group' at the World Health Organization, the Food and Agriculture Organization, Louisiana State University and the Danish Bilharziasis Laboratory with regional GIS networks to be initiated in Eastern Africa, Southern Africa, West Africa, Latin America and Southern Asia. An Internet site, www.gnosisGIS.org, (GIS Network On Snail-borne Infections with special reference to Schistosomiasis), has been initiated to allow interaction of team members as a 'virtual research group'. When completed, the site will point users to a toolbox of common resources resident on computers at member organizations, provide assistance on routine use of GIS health maps in selected national disease control

  7. The Scandinavian Propaten(®) trial - 1-year patency of PTFE vascular prostheses with heparin-bonded luminal surfaces compared to ordinary pure PTFE vascular prostheses - a randomised clinical controlled multi-centre trial

    DEFF Research Database (Denmark)

    Lindholt, J S; Gottschalksen, B; Johannesen, N

    2011-01-01

    To compare 1-year potencies' of heparin-bonded PTFE [(Hb-PTFE) (Propaten(®))] grafts with those of ordinary polytetraflouroethylene (PTFE) grafts in a blinded, randomised, clinically controlled, multi-centre study.......To compare 1-year potencies' of heparin-bonded PTFE [(Hb-PTFE) (Propaten(®))] grafts with those of ordinary polytetraflouroethylene (PTFE) grafts in a blinded, randomised, clinically controlled, multi-centre study....

  8. Modelling the impact of cyber attacks on the traffic control centre of an urban automobile transport system by means of enhanced cybersecurity

    Directory of Open Access Journals (Sweden)

    Ivanova Yoana

    2017-01-01

    Full Text Available This paper aims to show the major role means of protection play for strengthening the cybersecurity of critical transport infrastructure by using the advanced method of simulation modelling. The simulation model of a Traffic Control Centre (TTC of an urban Automobile Transport System (ATS is created by the author in the Riverbed Modeler Academic Edition 17.5 computer networks simulation system and is exposed to the impact of a Denial-of-Service attack. In addition, logical conclusions have been made on the basis of the experimental results obtained and evaluated by comparative analysis with results from analogous previous studies.

  9. Manufacturing and control of the aspherical mirrors for the telescope of the satellite Pleiades

    Science.gov (United States)

    Ducollet, Hélène; du Jeu, Christian; Fermé, Jean-Jacques

    2017-11-01

    For the Pleiades space program, SESO has been awarded the contract (fully completed), for the manufacturing of the whole set of telescope mirrors (4 mirrors, 2 flight models). These works did also include the mechanical design, manufacturing and mounting of the attachment flexures between the mirrors and the telescope main structure. This presentation is focused on the different steps of lightweighting, polishing, integration and control of these mirrors as well as a presentation of the existing SESO facilities and capabilities to produce such kind of aspherical components/sub-assemblies.

  10. The centre of the action

    CERN Multimedia

    2008-01-01

    The CERN Control Centre (CCC) has all the ingredients of an action movie control room: hundreds of screens, technicians buzzing in and out, huge floor-to-ceiling windows revealing the looming vista of a mountain range, flashing lights, microphones… This is the place where not just the LHC, but the whole of CERN’s accelerator complex and technical support is based - truly the centre of the action at CERN.

  11. The effect of sucrose as pain relief/comfort during immunisation of 15-month-old children in health care centres: a randomised controlled trial.

    Science.gov (United States)

    Despriee, Åshild Wik; Langeland, Eva

    2016-02-01

    To investigate the effect of 30% sucrose compared with a placebo (water) as pain relief and comfort during immunisation of 15-month-old children in health care centres. Children experience different levels of pain and distress during immunisation. Sweet solutions function as pain relief during immunisation for infants up to one year of age. However, there are few studies of older children. An experimental design in which the participants (15-month-old infants) were randomly assigned to an intervention group that received a 30% sugar solution or a control group that received a placebo (water). The study was performed at three health care centres in a large Norwegian municipality. The parents of all 15-month-old infants who were recommended for vaccination (for measles, mumps and rubella) between 5 September 2013 and 31 March 2014 were invited to have their infant participate. Duration of crying was the outcome measure. A total of 114 children were included (59 in the intervention group, 55 in the control group). The intervention group infants' crying was shorter (18 seconds mean) compared with the control group infants (33 seconds mean). The difference in crying duration between the groups was both statistically and clinically significant. This trial revealed that 30% sucrose orally has a calming and pain-relieving effect on 15-month-old infants during immunisation. Public health nurses should use a 30% sucrose solution for pain relief during immunisation of 15-month-old infants. © 2016 John Wiley & Sons Ltd.

  12. Centriolar satellites

    DEFF Research Database (Denmark)

    Tollenaere, Maxim A X; Mailand, Niels; Bekker-Jensen, Simon

    2015-01-01

    Centriolar satellites are small, microscopically visible granules that cluster around centrosomes. These structures, which contain numerous proteins directly involved in centrosome maintenance, ciliogenesis, and neurogenesis, have traditionally been viewed as vehicles for protein trafficking...... highlight newly discovered regulatory mechanisms targeting centriolar satellites and their functional status, and we discuss how defects in centriolar satellite components are intimately linked to a wide spectrum of human diseases....

  13. [Family doctor-centred care in Baden-Wuerttemberg: concept and results of a controlled evaluation study].

    Science.gov (United States)

    Gerlach, Ferdinand M; Szecsenyi, Joachim

    2013-01-01

    Pursuant to Section 73b, volume V of the German Social Security Code (SGB V), the agreement on family doctor-centred care (HzV), which went into effect in Baden-Wuerttemberg on July 1, 2008, provides for spatially inclusive and comprehensive medical coverage. The most important elements of the agreement are: the voluntary registration of family practices and patients, the strengthening of the coordinative function of family practices, the fulfilment of certain training, quality and qualification requirements, the standardised remuneration system and the use of specified practice software for billing and the prescription of drugs. The aim of this complex intervention is to strengthen family medicine, improve health care, in particular for patients with chronic disease, and to limit primary health care costs while improving its quality wherever possible. This first controlled nationwide evaluation examines the question whether these objectives were met in the early phase (2008 to 2011) and, if so, to what extent. Four work packages were defined: 1. differences in health care processes (utilisation, contact to specialists, hospitalisations, drug prescriptions); 2. developments in practice teams and of patient satisfaction; 3. deployment of specially trained health care assistants in family practices (VERAH); 4. implementation of the DEGAM (German Society of General Practice and Family Medicine) heart failure guideline. To the extent that it was possible to use the statutory health insurance company AOK Baden-Wuerttemberg's routine data, an adjusted comparison of the target variables was made for HzV- and non-HzV-insured patients between the first and second or between the third and fourth quarters of 2008, and between the first and second or third and fourth quarters of 2010. HzV participants were older, had a higher disease burden (Charlson Index 1.45 vs. 1.19), and were attended to more intensively than patients receiving routine care (1.7 more contacts with the

  14. Autonomous Satellite Command and Control through the World Wide Web: Phase 3

    Science.gov (United States)

    Cantwell, Brian; Twiggs, Robert

    1998-01-01

    management, modeling and fault management capabilities that integrate the space and ground segments of the space system hardware; (5) Implement a beacon monitoring test; (6) Implement an experimental blackboard controller for space system management; (7) Further define typical ground station developments required for Internet-based remote control and for full system automation of the PI-to-spacecraft link. Each of those goals is examined in the next section. Significant sections of this report were also published as a conference paper.

  15. Innovative power management, attitude determination and control tile for CubeSat standard NanoSatellites

    Science.gov (United States)

    Ali, Anwar; Mughal, M. Rizwan; Ali, Haider; Reyneri, Leonardo

    2014-03-01

    Electric power supply (EPS) and attitude determination and control subsystem (ADCS) are the most essential elements of any aerospace mission. Efficient EPS and precise ADCS are the core of any spacecraft mission. So keeping in mind their importance, they have been integrated and developed on a single tile called CubePMT module. Modular power management tiles (PMTs) are already available in the market but they are less efficient, heavier in weight, consume more power and contain less number of subsystems. Commercial of the shelf (COTS) components have been used for CubePMT implementation which are low cost and easily available from the market. CubePMT is developed on the design approach of AraMiS architecture: a project developed at Politecnico di Torino that provides low cost and higher performance space missions with dimensions larger than CubeSats. The feature of AraMiS design approach is its modularity. These modules can be reused for multiple missions which helps in significant reduction of the overall budget, development and testing time. One has just to reassemble the required subsystems to achieve the targeted specific mission.

  16. A pragmatic multi-centre randomised controlled trial of fluid loading and level of dependency in high-risk surgical patients undergoing major elective surgery: trial protocol

    Directory of Open Access Journals (Sweden)

    Norrie John

    2010-04-01

    Full Text Available Abstract Background Patients undergoing major elective or urgent surgery are at high risk of death or significant morbidity. Measures to reduce this morbidity and mortality include pre-operative optimisation and use of higher levels of dependency care after surgery. We propose a pragmatic multi-centre randomised controlled trial of level of dependency and pre-operative fluid therapy in high-risk surgical patients undergoing major elective surgery. Methods/Design A multi-centre randomised controlled trial with a 2 * 2 factorial design. The first randomisation is to pre-operative fluid therapy or standard regimen and the second randomisation is to routine intensive care versus high dependency care during the early post-operative period. We intend to recruit 204 patients undergoing major elective and urgent abdominal and thoraco-abdominal surgery who fulfil high-risk surgical criteria. The primary outcome for the comparison of level of care is cost-effectiveness at six months and for the comparison of fluid optimisation is the number of hospital days after surgery. Discussion We believe that the results of this study will be invaluable in determining the future care and clinical resource utilisation for this group of patients and thus will have a major impact on clinical practice. Trial Registration Trial registration number - ISRCTN32188676

  17. Controls on slow-moving landslides revealed by satellite and airborne InSAR

    Science.gov (United States)

    Handwerger, Alexander L.; Fielding, Eric J.

    2017-04-01

    Landslides display a wide variety of behaviors ranging from slow persistent motion to rapid acceleration and catastrophic failure. Given the variety of possible behaviors, improvements to our understanding of landslide mechanics are critical for accurate predictions of landslide dynamics. To better constrain the mechanisms that control landslide motion, we use recent SAR data collected by Copernicus Sentinel-1A/B, NASA UAVSAR, JAXA ALOS-2, and DLR TerraSAR-X to quantify the time-dependent kinematics of over 200 slow-moving landslides in the Central and Northern California Coast Ranges. These landslides are ideally suited for InSAR investigations due to their size (up to 5 km in length and 0.5 km in width), persistent downslope motion with low velocities (m/yr), and sparse vegetation. We quantify the seasonal and multi-year changes in velocity driven by changes in precipitation and find that landslide velocity varies over both timescales. Over seasonal timescales, each landslide displays a period of acceleration that occurs within weeks of the onset of seasonal rainfall suggesting that motion is governed by precipitation-induced changes in pore-water pressure. We also examine the effects of multi-year climate variations (i.e., recent historic California drought and the possible wet period that began in late 2016) on the activity of landslides. We find that the drought has led to a decrease in annual displacement over the past several years and predict that a resurgence in annual displacement will occur with an increase in annual rainfall. Lastly, we use UAVSAR data acquired at 4 different look directions to quantify 3D surface displacement of multiple landslides and invert for their subsurface geometry (i.e. basal slip surface) using recently developed 3D mass conservation techniques. The application of NASA's UAVSAR data represents a major advance from previous InSAR studies on landslides in this region and provides one of the first 3D dataset that contains

  18. Supporting Development of Satellite's Guidance Navigation and Control Software: A Product Line Approach

    Science.gov (United States)

    McComas, David; Stark, Michael; Leake, Stephen; White, Michael; Morisio, Maurizio; Travassos, Guilherme H.; Powers, Edward I. (Technical Monitor)

    2000-01-01

    The NASA Goddard Space Flight Center Flight Software Branch (FSB) is developing a Guidance, Navigation, and Control (GNC) Flight Software (FSW) product line. The demand for increasingly more complex flight software in less time while maintaining the same level of quality has motivated us to look for better FSW development strategies. The GNC FSW product line has been planned to address the core GNC FSW functionality very similar on many recent low/near Earth missions in the last ten years. Unfortunately these missions have not accomplished significant drops in development cost since a systematic approach towards reuse has not been adopted. In addition, new demands are continually being placed upon the FSW which means the FSB must become more adept at providing GNC FSW functionality's core so it can accommodate additional requirements. These domain features together with engineering concepts are influencing the specification, description and evaluation of FSW product line. Domain engineering is the foundation for emerging product line software development approaches. A product line is 'A family of products designed to take advantage of their common aspects and predicted variabilities'. In our product line approach, domain engineering includes the engineering activities needed to produce reusable artifacts for a domain. Application engineering refers to developing an application in the domain starting from reusable artifacts. The focus of this paper is regarding the software process, lessons learned and on how the GNC FSW product line manages variability. Existing domain engineering approaches do not enforce any specific notation for domain analysis or commonality and variability analysis. Usually, natural language text is the preferred tool. The advantage is the flexibility and adapt ability of natural language. However, one has to be ready to accept also its well-known drawbacks, such as ambiguity, inconsistency, and contradictions. While most domain analysis

  19. Satellite Communications

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Satellite Communications. Arthur C Clarke wrote a seminal paper in 1945 in wireless world. Use three satellites in geo-synchronous orbit to enable intercontinental communications. System could be realised in '50 to 100 years'

  20. The Use of a Satellite Communications System for Command and Control of the National Aeronautics and Space Administration Surrogate Unmanned Aerial System Research Aircraft

    Science.gov (United States)

    Howell, Charles T.; Jones, Frank; Hutchinson, Brian; Joyce, Claude; Nelson, Skip; Melum, Mike

    2017-01-01

    The NASA Langley Research Center has transformed a Cirrus Design SR22 general aviation (GA) aircraft into an Unmanned Aerial Systems (UAS) Surrogate research aircraft which has served for several years as a platform for unmanned systems research and development. The aircraft is manned with a Safety Pilot and a Research Systems Operator (RSO) that allows for flight operations almost any-where in the national airspace system (NAS) without the need for a Federal Aviation Administration (FAA) Certificate of Authorization (COA). The UAS Surrogate can be remotely controlled from a modular, transportable ground control station (GCS) like a true UAS. Ground control of the aircraft is accomplished by the use of data links that allow the two-way passage of the required data to control the aircraft and provide the GCS with situational awareness. The original UAS Surrogate data-link system was composed of redundant very high frequency (VHF) data radio modems with a maximum range of approximately 40 nautical miles. A new requirement was developed to extend this range beyond visual range (BVR). This new requirement led to the development of a satellite communications system that provided the means to command and control the UAS Surrogate at ranges beyond the limits of the VHF data links. The system makes use of the Globalstar low earth orbit (LEO) satellite communications system. This paper will provide details of the development, implementation, and flight testing of the satellite data communications system on the UAS Surrogate research aircraft.

  1. Iodine Satellite

    Science.gov (United States)

    Kamhawi, Hani; Dankanich, John; Martinez, Andres; Petro, Andrew

    2015-01-01

    The Iodine Satellite (iSat) spacecraft will be the first CubeSat to demonstrate high change in velocity from a primary propulsion system by using Hall thruster technology and iodine as a propellant. The mission will demonstrate CubeSat maneuverability, including plane change, altitude change and change in its closest approach to Earth to ensure atmospheric reentry in less than 90 days. The mission is planned for launch in fall 2017. Hall thruster technology is a type of electric propulsion. Electric propulsion uses electricity, typically from solar panels, to accelerate the propellant. Electric propulsion can accelerate propellant to 10 times higher velocities than traditional chemical propulsion systems, which significantly increases fuel efficiency. To enable the success of the propulsion subsystem, iSat will also demonstrate power management and thermal control capabilities well beyond the current state-of-the-art for spacecraft of its size. This technology is a viable primary propulsion system that can be used on small satellites ranging from about 22 pounds (10 kilograms) to more than 1,000 pounds (450 kilograms). iSat's fuel efficiency is ten times greater and its propulsion per volume is 100 times greater than current cold-gas systems and three times better than the same system operating on xenon. iSat's iodine propulsion system consists of a 200 watt (W) Hall thruster, a cathode, a tank to store solid iodine, a power processing unit (PPU) and the feed system to supply the iodine. This propulsion system is based on a 200 W Hall thruster developed by Busek Co. Inc., which was previously flown using xenon as the propellant. Several improvements have been made to the original system to include a compact PPU, targeting greater than 80 percent reduction in mass and volume of conventional PPU designs. The cathode technology is planned to enable heaterless cathode conditioning, significantly increasing total system efficiency. The feed system has been designed to

  2. The Aube centre; Le Centre de l`Aube

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    This educational booklet is devoted to a general presentation of the Aube radioactive wastes storage centre. After a short presentation of the Andra, the French national agency for the management of radioactive wastes, it gives some general information about radioactive wastes (origin, classification), containers (quality assurance and different types), wastes transportation (planning, safety), and about the Aube centre itself: description, treatment and conditioning of drums (compacting and injection), storage facilities, geological situation of the site, and environmental controls. (J.S.)

  3. Estimation of content of anti-TB drugs supplied at centres of the Revised National TB Control Programme in Tamil Nadu, India.

    Science.gov (United States)

    Ramachandran, Geetha; Chandrasekaran, Vedachalam; Hemanth Kumar, Agibothu Kupparam; Dewan, Puneet; Swaminathan, Soumya; Thomas, Aleyamma

    2013-09-01

    To determine the content of certain antituberculosis (TB) drugs supplied at TB treatment centres of the Revised National TB Control Programme (RNTCP) in the state of Tamil Nadu, India. Eight districts across the state were selected, and the following drugs were collected from five settings (District TB centre, TB unit, designated microscopy centres, DOT providers) in each district: rifampicin (150 and 450 mg), isoniazid (300 mg), pyrazinamide (500 and 750 mg), ethambutol (400 and 600 mg), ethionamide (250 mg), levofloxacin (500 mg) and cycloserine (250 mg). A maximum of 10 tablets/capsules were collected from each setting. The drugs were coded prior to analysis. All drugs were assayed by validated spectrophotometric methods. The acceptable limits for drug content were taken as 90-110% of the stated content. More than 90% of tablets of rifampicin 450 mg, isoniazid 300 mg, pyrazinamide 500 and 750 mg, ethambutol 400 and 600 mg and ethionamide 250 mg were within acceptable limits. Eighty per cent of rifampicin 150 mg, 21% of cycloserine 250 mg and 87% of levofloxacin 500 mg were within acceptable limits. The mean cycloserine content was below the acceptable limit in all districts, the mean drug content being 200 mg (range: 108-245 mg). This systematic study showed that the stated drug content of cycloserine was not reached in all districts. Deterioration of cycloserine could be minimised by storing the drug in refrigerators. The geographical location of the districts had no influence on the drug content. © 2013 John Wiley & Sons Ltd.

  4. Multi-port versus single-port cholecystectomy: results of a multi-centre, randomised controlled trial (MUSIC trial).

    Science.gov (United States)

    Arezzo, Alberto; Passera, Roberto; Bullano, Alberto; Mintz, Yoav; Kedar, Asaf; Boni, Luigi; Cassinotti, Elisa; Rosati, Riccardo; Fumagalli Romario, Uberto; Sorrentino, Mario; Brizzolari, Marco; Di Lorenzo, Nicola; Gaspari, Achille Lucio; Andreone, Dario; De Stefani, Elena; Navarra, Giuseppe; Lazzara, Salvatore; Degiuli, Maurizio; Shishin, Kirill; Khatkov, Igor; Kazakov, Ivan; Schrittwieser, Rudolf; Carus, Thomas; Corradi, Alessio; Sitzman, Guenther; Lacy, Antonio; Uranues, Selman; Szold, Amir; Morino, Mario

    2017-07-01

    Single-port laparoscopic surgery as an alternative to conventional laparoscopic cholecystectomy for benign disease has not yet been accepted as a standard procedure. The aim of the multi-port versus single-port cholecystectomy trial was to compare morbidity rates after single-access (SPC) and standard laparoscopy (MPC). This non-inferiority phase 3 trial was conducted at 20 hospital surgical departments in six countries. At each centre, patients were randomly assigned to undergo either SPC or MPC. The primary outcome was overall morbidity within 60 days after surgery. Analysis was by intention to treat. The study was registered with ClinicalTrials.gov (NCT01104727). The study was conducted between April 2011 and May 2015. A total of 600 patients were randomly assigned to receive either SPC (n = 297) or MPC (n = 303) and were eligible for data analysis. Postsurgical complications within 60 days were recorded in 13 patients (4.7 %) in the SPC group and in 16 (6.1 %) in the MPC group (P = 0.468); however, single-access procedures took longer [70 min (range 25-265) vs. 55 min (range 22-185); P risk of incisional hernia following SPC do not appear to be justified. Patient satisfaction with aesthetic results was greater after SPC than after MPC.

  5. Impact of person-centred care training and person-centred activities on quality of life, agitation, and antipsychotic use in people with dementia living in nursing homes: A cluster-randomised controlled trial.

    Directory of Open Access Journals (Sweden)

    Clive Ballard

    2018-02-01

    Full Text Available Agitation is a common, challenging symptom affecting large numbers of people with dementia and impacting on quality of life (QoL. There is an urgent need for evidence-based, cost-effective psychosocial interventions to improve these outcomes, particularly in the absence of safe, effective pharmacological therapies. This study aimed to evaluate the efficacy of a person-centred care and psychosocial intervention incorporating an antipsychotic review, WHELD, on QoL, agitation, and antipsychotic use in people with dementia living in nursing homes, and to determine its cost.This was a randomised controlled cluster trial conducted between 1 January 2013 and 30 September 2015 that compared the WHELD intervention with treatment as usual (TAU in people with dementia living in 69 UK nursing homes, using an intention to treat analysis. All nursing homes allocated to the intervention received staff training in person-centred care and social interaction and education regarding antipsychotic medications (antipsychotic review, followed by ongoing delivery through a care staff champion model. The primary outcome measure was QoL (DEMQOL-Proxy. Secondary outcomes were agitation (Cohen-Mansfield Agitation Inventory [CMAI], neuropsychiatric symptoms (Neuropsychiatric Inventory-Nursing Home Version [NPI-NH], antipsychotic use, global deterioration (Clinical Dementia Rating, mood (Cornell Scale for Depression in Dementia, unmet needs (Camberwell Assessment of Need for the Elderly, mortality, quality of interactions (Quality of Interactions Scale [QUIS], pain (Abbey Pain Scale, and cost. Costs were calculated using cost function figures compared with usual costs. In all, 847 people were randomised to WHELD or TAU, of whom 553 completed the 9-month randomised controlled trial. The intervention conferred a statistically significant improvement in QoL (DEMQOL-Proxy Z score 2.82, p = 0.0042; mean difference 2.54, SEM 0.88; 95% CI 0.81, 4.28; Cohen's D effect size 0

  6. Surgical timing after chemoradiotherapy for rectal cancer, analysis of technique (STARRCAT): results of a feasibility multi-centre randomized controlled trial.

    Science.gov (United States)

    Foster, J D; Ewings, P; Falk, S; Cooper, E J; Roach, H; West, N P; Williams-Yesson, B A; Hanna, G B; Francis, N K

    2016-10-01

    The optimal time of rectal resection after long-course chemoradiotherapy (CRT) remains unclear. A feasibility study was undertaken for a multi-centre randomized controlled trial evaluating the impact of the interval after chemoradiotherapy on the technical complexity of surgery. Patients with rectal cancer were randomized to either a 6- or 12-week interval between CRT and surgery between June 2012 and May 2014 (ISRCTN registration number: 88843062). For blinded technical complexity assessment, the Observational Clinical Human Reliability Analysis technique was used to quantify technical errors enacted within video recordings of operations. Other measured outcomes included resection completeness, specimen quality, radiological down-staging, tumour cell density down-staging and surgeon-reported technical complexity. Thirty-one patients were enrolled: 15 were randomized to 6 and 16-12 weeks across 7 centres. Fewer eligible patients were identified than had been predicted. Of 23 patients who underwent resection, mean 12.3 errors were observed per case at 6 weeks vs. 10.7 at 12 weeks (p = 0.401). Other measured outcomes were similar between groups. The feasibility of measurement of operative performance of rectal cancer surgery as an endpoint was confirmed in this exploratory study. Recruitment of sufficient numbers of patients represented a challenge, and a proportion of patients did not proceed to resection surgery. These results suggest that interval after CRT may not substantially impact upon surgical technical performance.

  7. Satellite Communications

    CERN Document Server

    Pelton, Joseph N

    2012-01-01

    The field of satellite communications represents the world's largest space industry. Those who are interested in space need to understand the fundamentals of satellite communications, its technology, operation, business, economic, and regulatory aspects. This book explains all this along with key insights into the field's future growth trends and current strategic challenges. Fundamentals of Satellite Communications is a concise book that gives all of the key facts and figures as well as a strategic view of where this dynamic industry is going. Author Joseph N. Pelton, PhD, former Dean of the International Space University and former Director of Strategic Policy at Intelstat, presents a r

  8. Does quality control matter? Surface urban heat island intensity variations estimated by satellite-derived land surface temperature products

    Science.gov (United States)

    Lai, Jiameng; Zhan, Wenfeng; Huang, Fan; Quan, Jinling; Hu, Leiqiu; Gao, Lun; Ju, Weimin

    2018-05-01

    The temporally regular and spatially comprehensive monitoring of surface urban heat islands (SUHIs) have been extremely difficult, until the advent of satellite-based land surface temperature (LST) products. However, these LST products have relatively higher errors compared to in situ measurements. This has resulted in comparatively inaccurate estimations of SUHI indicators and, consequently, may have distorted interpretations of SUHIs. Although reports have shown that LST qualities are important for SUHI interpretations, systematic investigations of the response of SUHI indicators to LST qualities across cities with dissimilar bioclimates are rare. To address this issue, we chose eighty-six major cities across mainland China and analyzed SUHI intensity (SUHII) derived from Moderate Resolution Imaging Spectroradiometer (MODIS) LST data. The LST-based SUHII differences due to inclusion or exclusion of MODIS quality control (QC) flags (i.e., ΔSUHII) were evaluated. Our major findings included, but are not limited to, the following four aspects: (1) SUHIIs can be significantly impacted by MODIS QC flags, and the associated QC-induced ΔSUHIIs generally accounted for 24.3% (29.9%) of the total SUHII value during the day (night); (2) the ΔSUHIIs differed between seasons, with considerable differences between transitional (spring and autumn) and extreme (summer and winter) seasons; (3) significant discrepancies also appeared among cities located in northern and southern regions, with northern cities often possessing higher annual mean ΔSUHIIs. The internal variations of ΔSUHIIs within individual cities also showed high heterogeneity, with ΔSUHII variations that generally exceeded 5.0 K (3.0 K) in northern (southern) cities; (4) ΔSUHIIs were negatively related to SUHIIs and cloud cover percentages (mostly in transitional seasons). No significant relationship was found in the extreme seasons. Our findings highlight the need to be extremely cautious when using LST

  9. Handbook of satellite applications

    CERN Document Server

    Madry, Scott; Camacho-Lara, Sergio

    2013-01-01

    Top space experts from around the world have collaborated to produce this comprehensive, authoritative, and clearly illustrated reference guide to the fast growing, multi-billion dollar field of satellite applications and space communications. This handbook, done under the auspices of the International Space University based in France, addresses not only system technologies but also examines market dynamics, technical standards and regulatory constraints. The handbook is a completely multi-disciplinary reference book that covers, in an in-depth fashion, the fields of satellite telecommunications, Earth observation, remote sensing, satellite navigation, geographical information systems, and geosynchronous meteorological systems. It covers current practices and designs as well as advanced concepts and future systems. It provides a comparative analysis of the common technologies and design elements for satellite application bus structures, thermal controls, power systems, stabilization techniques, telemetry, com...

  10. Efficacy of night-time compression for breast cancer related lymphedema (LYNC): protocol for a multi-centre, randomized controlled efficacy trial

    International Nuclear Information System (INIS)

    McNeely, Margaret L.; Campbell, Kristin L.; Webster, Marc; Kuusk, Urve; Tracey, Karen; Mackey, John

    2016-01-01

    Lymphedema is a prevalent long-term effect of breast cancer treatment that is associated with reduced quality of life. More recent observational data suggest that the addition of night-time compression to day-time use of a compression garment results in better long-term control of arm lymphedema. The primary objectives of the randomized controlled phase of the trial are to determine the efficacy of night-time compression on arm lymphedema volume maintenance and quality of life in breast cancer survivors who have completed intensive reduction treatment for their lymphedema. The study will be a parallel 3-arm, multi-centre randomized fast-track trial. A total of 120 women with breast cancer related lymphedema will be recruited from 3 centres in Canada and randomized to group 1: Day-time compression garment alone or Group 2: Day-time compression garment + night-time compression bandaging or Group 3: Day-time compression garment + use of a night-time compression system garment. The duration of the primary intervention period will be 12 weeks. The follow-up period after the intervention (weeks 13 to 24) will follow a longitudinal observational design. The primary outcome variables: differences from baseline to week 12 in arm volume and quality of life (Lymphoedema Functioning, Disability and Health Questionnaire: Lymph-ICF). Secondary outcomes include bioimpedance analysis, sleep disturbance and self-efficacy. All measurements are standardized and will be performed prior to randomization, and at weeks 6, 12, 18 and 24. The use of night-time compression as a self-management strategy for chronic breast cancer related lymphedema is seen as an innovative approach to improve long-term control over the condition. This trial aims to advance the knowledge on self-management strategies for lymphedema

  11. Factors controlling the redox potential of ZnCe6 in an engineered bacterioferritin photochemical 'reaction centre'.

    Science.gov (United States)

    Mahboob, Abdullah; Vassiliev, Serguei; Poddutoori, Prashanth K; van der Est, Art; Bruce, Doug

    2013-01-01

    Photosystem II (PSII) of photosynthesis has the unique ability to photochemically oxidize water. Recently an engineered bacterioferritin photochemical 'reaction centre' (BFR-RC) using a zinc chlorin pigment (ZnCe6) in place of its native heme has been shown to photo-oxidize bound manganese ions through a tyrosine residue, thus mimicking two of the key reactions on the electron donor side of PSII. To understand the mechanism of tyrosine oxidation in BFR-RCs, and explore the possibility of water oxidation in such a system we have built an atomic-level model of the BFR-RC using ONIOM methodology. We studied the influence of axial ligands and carboxyl groups on the oxidation potential of ZnCe6 using DFT theory, and finally calculated the shift of the redox potential of ZnCe6 in the BFR-RC protein using the multi-conformational molecular mechanics-Poisson-Boltzmann approach. According to our calculations, the redox potential for the first oxidation of ZnCe6 in the BRF-RC protein is only 0.57 V, too low to oxidize tyrosine. We suggest that the observed tyrosine oxidation in BRF-RC could be driven by the ZnCe6 di-cation. In order to increase the efficiency of tyrosine oxidation, and ultimately oxidize water, the first potential of ZnCe6 would have to attain a value in excess of 0.8 V. We discuss the possibilities for modifying the BFR-RC to achieve this goal.

  12. A randomized controlled trial of a senior centre group programme for increasing social support and preventing depression in elderly people living at home in Norway

    Directory of Open Access Journals (Sweden)

    Bøen Hege

    2012-05-01

    Full Text Available Abstract Background Late-life depression is a common condition and a challenging public health problem. A lack of social support is strongly associated with psychological distress. Senior centres seem to be suitable arenas for community-based health promotion interventions, although few studies have addressed this subject. The objectives were to examine the effect of a preventive senior centre group programme consisting of weekly meetings, on social support, depression and quality of life. Methods A questionnaire was sent to a random sample of 4,000 persons over 65 in Oslo, and a total of 2,387 completed questionnaires were obtained. These subjects served as a basis for recruitment of participants for a trial, with scores on HSCL-10 being used as a main inclusion criterion. A total of 138 persons were randomized into an intervention group (N = 77 and control group (N = 61. Final analyses included 92 persons. Social support (OSS-3, depression (BDI, life satisfaction and health were measured in interviews at baseline and after 12 months (at the end of the intervention programme. Perceptions of benefits from the intervention were also measured. Mean scores, SD, SE and CI were used to describe the changes in outcomes. Effect sizes were calculated based on the original scales and as Cohen’s d. Paired sample tests and ANOVA were used to test group differences. Results There was an increase in social support in both groups, but greatest in the intervention group. The level of depression increased for both groups, but more so in the control than the intervention group. There was a decrease in life satisfaction, although the decrease was largest among controls. There were almost no differences in reported health between groups. However, effect sizes were small and differences were not statistically significant. In contrast, most of the participants said the intervention meant much to them and led to increased use of the centre. Conclusions In

  13. Improving person-centred care in nursing homes through dementia-care mapping: design of a cluster-randomised controlled trial

    Science.gov (United States)

    2012-01-01

    Background The effectiveness and efficiency of nursing-home dementia care are suboptimal: there are high rates of neuropsychiatric symptoms among the residents and work-related stress among the staff. Dementia-care mapping is a person-centred care method that may alleviate both the resident and the staff problems. The main objective of this study is to evaluate the effectiveness and cost-effectiveness of dementia-care mapping in nursing-home dementia care. Methods/Design The study is a cluster-randomised controlled trial, with nursing homes grouped in clusters. Studywise minimisation is the allocation method. Nursing homes in the intervention group will receive a dementia-care-mapping intervention, while the control group will receive usual care. The primary outcome measure is resident agitation, to be assessed with the Cohen-Mansfield Agitation Inventory. The secondary outcomes are resident neuropsychiatric symptoms, assessed with the Neuropsychiatric Inventory - Nursing Homes and quality of life, assessed with Qualidem and the EQ-5D. The staff outcomes are stress reactions, job satisfaction and job-stress-related absenteeism, and staff turnover rate, assessed with the Questionnaire about Experience and Assessment of Work, the General Health Questionnaire-12, and the Maastricht Job Satisfaction Scale for Health Care, respectively. We will collect the data from the questionnaires and electronic registration systems. We will employ linear mixed-effect models and cost-effectiveness analyses to evaluate the outcomes. We will use structural equation modelling in the secondary analysis to evaluate the plausibility of a theoretical model regarding the effectiveness of the dementia-care mapping intervention. We will set up process analyses, including focus groups with staff, to determine the relevant facilitators of and barriers to implementing dementia-care mapping broadly. Discussion A novelty of dementia-care mapping is that it offers an integral person-centred

  14. Improving person-centred care in nursing homes through dementia-care mapping: design of a cluster-randomised controlled trial

    Directory of Open Access Journals (Sweden)

    van de Ven Geertje

    2012-01-01

    Full Text Available Abstract Background The effectiveness and efficiency of nursing-home dementia care are suboptimal: there are high rates of neuropsychiatric symptoms among the residents and work-related stress among the staff. Dementia-care mapping is a person-centred care method that may alleviate both the resident and the staff problems. The main objective of this study is to evaluate the effectiveness and cost-effectiveness of dementia-care mapping in nursing-home dementia care. Methods/Design The study is a cluster-randomised controlled trial, with nursing homes grouped in clusters. Studywise minimisation is the allocation method. Nursing homes in the intervention group will receive a dementia-care-mapping intervention, while the control group will receive usual care. The primary outcome measure is resident agitation, to be assessed with the Cohen-Mansfield Agitation Inventory. The secondary outcomes are resident neuropsychiatric symptoms, assessed with the Neuropsychiatric Inventory - Nursing Homes and quality of life, assessed with Qualidem and the EQ-5D. The staff outcomes are stress reactions, job satisfaction and job-stress-related absenteeism, and staff turnover rate, assessed with the Questionnaire about Experience and Assessment of Work, the General Health Questionnaire-12, and the Maastricht Job Satisfaction Scale for Health Care, respectively. We will collect the data from the questionnaires and electronic registration systems. We will employ linear mixed-effect models and cost-effectiveness analyses to evaluate the outcomes. We will use structural equation modelling in the secondary analysis to evaluate the plausibility of a theoretical model regarding the effectiveness of the dementia-care mapping intervention. We will set up process analyses, including focus groups with staff, to determine the relevant facilitators of and barriers to implementing dementia-care mapping broadly. Discussion A novelty of dementia-care mapping is that it offers an

  15. Application of the user-centred design process according ISO 9241-210 in air traffic control.

    Science.gov (United States)

    König, Christina; Hofmann, Thomas; Bruder, Ralph

    2012-01-01

    Designing a usable human machine interface for air traffic control is challenging and should follow approved methods. The ISO 9241-210 standard promises high usability of products by integrating future users and following an iterative process. This contribution describes the proceeding and first results of the analysis and application of ISO 9241-210 to develop a planning tool for air traffic controllers.

  16. Satellite Geomagnetism

    DEFF Research Database (Denmark)

    Olsen, Nils; Stolle, Claudia

    2012-01-01

    Observations of Earth’s magnetic field from space began more than 50 years ago. A continuous monitoring of the field using low Earth orbit (LEO) satellites, however, started only in 1999, and three satellites have taken highprecision measurements of the geomagnetic field during the past decade....... The unprecedented time-space coverage of their data opened revolutionary new possibilities for monitoring, understanding, and exploring Earth’s magnetic field. In the near future, the three-satellite constellation Swarm will ensure continuity of such measurement and provide enhanced possibilities to improve our...... ability to characterize and understand the many sources that contribute to Earth’s magnetic field. In this review, we summarize investigations of Earth’s interior and environment that have been possible through the analysis of high-precision magnetic field observations taken by LEO satellites....

  17. GLONASS satellite monitoring of nuclear transports

    International Nuclear Information System (INIS)

    Davydov, Yu.L.

    2012-01-01

    In 2011 Rosatom has made the decision to create the industry-wide automated system for monitoring of transports of radioactive substances (RS) and wastes (RAW), as well as hazardous loads by rail and automobile, based upon the same hardware as used by the GLONASS satellite navigation system - the so-called ASBT-GLONASS system. The new system will use the same technical infrastructure as the existing operational Automated System for Safe Transport of Nuclear Materials of Categories I and II (ASBT). The ASBT structure includes a network of control centres fitted with automation and communication hardware. In addition, ASBT includes technical complexes installed upon transport vehicles intended for nuclear material transport. In order to identify transport vehicle location, the GLONASS/GPS (GALS-P-ASBT) satellite navigational receiver device is used, it is developed especially for ASBT systems taking in account information security requirements. By now the basic software and hardware complex ASBT-GLONASS has been created (equipment to be carried on-board the transport vehicle loaded with RS and RAW, as well as the transport control stations) that supports transport monitoring and transmission of an emergency signal to control stations of companies which deal with RS and RAW transportation [ru

  18. Boomerang Satellites

    Science.gov (United States)

    Hesselbrock, Andrew; Minton, David A.

    2017-10-01

    We recently reported that the orbital architecture of the Martian environment allows for material in orbit around the planet to ``cycle'' between orbiting the planet as a ring, or as coherent satellites. Here we generalize our previous analysis to examine several factors that determine whether satellites accreting at the edge of planetary rings will cycle. In order for the orbiting material to cycle, tidal evolution must decrease the semi-major axis of any accreting satellites. In some systems, the density of the ring/satellite material, the surface mass density of the ring, the tidal parameters of the system, and the rotation rate of the primary body contribute to a competition between resonant ring torques and tidal dissipation that prevent this from occurring, either permanently or temporarily. Analyzing these criteria, we examine various bodies in our solar system (such as Saturn, Uranus, and Eris) to identify systems where cycling may occur. We find that a ring-satellite cycle may give rise to the current Uranian ring-satellite system, and suggest that Miranda may have formed from an early, more massive Uranian ring.

  19. Criticality analysis of the EU gas infrastructure: heightened security requirements for gas control and management centres; Kritikalitaetsanalyse der EU-Gasinfrastruktur: Erhoehte Sicherheitsanforderungen an Gasleit- und -kontrollzentren

    Energy Technology Data Exchange (ETDEWEB)

    Nerlich, Uwe; Umbach, Frank [Centre for European Security Strategies (CESS), Muenchen/Berlin (Germany)

    2009-11-15

    Since the terror attacks of 2001 critical infrastructure objects have gained substantially in strategic importance in the eyes of the German government and EU authorities as well as the European industry. This has not only been due to the worldwide increase in terrorist attacks on energy infrastructure objects but also to the attacks of Madrid on 11 March 2004 and London on 7 July 2005, which have shown that Europe is no longer being spared from terrorism. Strategies for the abatement of these hazards and their repercussions are therefore more urgently needed than ever before. This requires a differentiated assessment of the situation, as has been carried out, for example, in raising the security requirements and investigating the vulnerability of the gas management and control centres of the EU's Octavio project.

  20. Design and performance of a multi-centre randomised controlled trial and economic evaluation of joint tele-consultations [ISRCTN54264250

    Directory of Open Access Journals (Sweden)

    Thompson Simon

    2002-01-01

    Full Text Available Abstract Background Appropriate information flow is crucial to the care of patients, particularly at the interface between primary and secondary care. Communication problems can result from inadequate organisation and training, There is a major expectation that information and communication technologies may offer solutions, but little reliable evidence. This paper reports the design and performance of a multi-centre randomised controlled trial (RCT, unparalleled in telemedicine research in either scale or range of outcomes. The study investigated the effectiveness and cost implications in rural and inner-city settings of using videoconferencing to perform joint tele-consultations as an alternative to general practitioner referral to the hospital specialist in the outpatient clinic. Methods Joint tele-consultation services were established in both the Royal Free Hampstead NHS Trust in inner London, and the Royal Shrewsbury Hospitals Trust, in Shropshire. All the patients who gave consent to participate were randomised either to joint tele-consultation or to a routine outpatients appointment. The principal outcome measures included the frequency of decision by the specialist to offer a follow-up outpatient appointment, patient satisfaction (Ware Specific Questionnaire, wellbeing (SF12 and enablement (PEI, numbers of tests, investigations, procedures and treatments. Results A total of 134 general practitioners operating from 29 practices participated in the trial, referring a total of 3170 patients to 20 specialists in ENT medicine, general medicine (including endocrinology, and rheumatology, gastroenterology, orthopaedics, neurology and urology. Of these, 2094 patients consented to participate in the study and were correctly randomised. There was a 91% response rate to the initial assessment questionnaires, and analysis showed equivalence for all key characteristics between the treatment and control groups. Conclusion We have designed and

  1. An organisational change intervention for increasing the delivery of smoking cessation support in addiction treatment centres: study protocol for a randomized controlled trial.

    Science.gov (United States)

    Bonevski, Billie; Guillaumier, Ashleigh; Shakeshaft, Anthony; Farrell, Michael; Tzelepis, Flora; Walsberger, Scott; D'Este, Catherine; Paul, Chris; Dunlop, Adrian; Searles, Andrew; Kelly, Peter; Fry, Rae; Stirling, Robert; Fowlie, Carrie; Skelton, Eliza

    2016-06-14

    The provision of smoking cessation support in Australian drug and alcohol treatment services is sub-optimal. This study examines the cost-effectiveness of an organisational change intervention to reduce smoking amongst clients attending drug and alcohol treatment services. A cluster-randomised controlled trial will be conducted with drug and alcohol treatment centres as the unit of randomisation. Biochemically verified (carbon monoxide by breath analysis) client 7-day-point prevalence of smoking cessation at 6 weeks will be the primary outcome measure. The study will be conducted in 33 drug and alcohol treatment services in four mainland states and territories of Australia: New South Wales, Australian Capital Territory, Queensland, and South Australia. Eligible services are those with ongoing client contact and that include pharmacotherapy services, withdrawal management services, residential rehabilitation, counselling services, and case management services. Eligible clients are those aged over 16 years who are attending their first of a number of expected visits, are self-reported current smokers, proficient in the English language, and do not have severe untreated mental illness as identified by the service staff. Control services will continue to provide usual care to the clients. Intervention group services will receive an organisational change intervention, including assistance in developing smoke-free policies, nomination of champions, staff training and educational client and service resources, and free nicotine replacement therapy in order to integrate smoking cessation support as part of usual client care. If effective, the organisational change intervention has clear potential for implementation as part of the standard care in drug and alcohol treatment centres. Australian and New Zealand Clinical Trials Registry, ACTRN12615000204549 . Registered on 3 March 2015.

  2. Intensity modulated radiation therapy: Analysis of patient specific quality control results, experience of Rene-Gauducheau Centre; Radiotherapie conformationnelle avec modulation d'intensite: analyse des resultats des controles precliniques, experience du centre Rene-Gauducheau

    Energy Technology Data Exchange (ETDEWEB)

    Chiavassa, S.; Brunet, G.; Gaudaire, S.; Munos-Llagostera, C.; Delpon, G.; Lisbona, A. [Service de physique medicale, centre Rene-Gauducheau, CLCC Nantes Atlantique, site hospitalier Nord, boulevard Jacques-Monod, 44805 Nantes Saint-Herblain cedex (France)

    2011-07-15

    Purpose. - Systematic verifications of patient's specific intensity-modulated radiation treatments are usually performed with absolute and relative measurements. The results constitute a database which allows the identification of potential systematic errors. Material and methods. - We analyzed 1270 beams distributed in 232 treatment plans. Step-and-shoot intensity-modulated radiation treatments were performed with a Clinac (6 and 23 MV) and sliding window intensity-modulated radiation treatments with a Novalis (6 MV). Results. - The distributions obtained do not show systematic error and all the control meet specified tolerances. Conclusion. - These results allow us to reduce controls specific patients for treatments performed under identical conditions (location, optimization and segmentation parameters of treatment planning system, etc.). (authors)

  3. The Effects of Clinical Hypnosis versus Neurolinguistic Programming (NLP before External Cephalic Version (ECV: A Prospective Off-Centre Randomised, Double-Blind, Controlled Trial

    Directory of Open Access Journals (Sweden)

    Joscha Reinhard

    2012-01-01

    Full Text Available Objective. To examine the effects of clinical hypnosis versus NLP intervention on the success rate of ECV procedures in comparison to a control group. Methods. A prospective off-centre randomised trial of a clinical hypnosis intervention against NLP of women with a singleton breech fetus at or after 370/7 (259 days weeks of gestation and normal amniotic fluid index. All 80 participants heard a 20-minute recorded intervention via head phones. Main outcome assessed was success rate of ECV. The intervention groups were compared with a control group with standard medical care alone (=122. Results. A total of 42 women, who received a hypnosis intervention prior to ECV, had a 40.5% (=17, successful ECV, whereas 38 women, who received NLP, had a 44.7% (=17 successful ECV (>0.05. The control group had similar patient characteristics compared to the intervention groups (>0.05. In the control group (=122 27.3% (=33 had a statistically significant lower successful ECV procedure than NLP (=0.05 and hypnosis and NLP (=0.03. Conclusions. These findings suggest that prior clinical hypnosis and NLP have similar success rates of ECV procedures and are both superior to standard medical care alone.

  4. The Effects of Clinical Hypnosis versus Neurolinguistic Programming (NLP) before External Cephalic Version (ECV): A Prospective Off-Centre Randomised, Double-Blind, Controlled Trial.

    Science.gov (United States)

    Reinhard, Joscha; Peiffer, Swati; Sänger, Nicole; Herrmann, Eva; Yuan, Juping; Louwen, Frank

    2012-01-01

    Objective. To examine the effects of clinical hypnosis versus NLP intervention on the success rate of ECV procedures in comparison to a control group. Methods. A prospective off-centre randomised trial of a clinical hypnosis intervention against NLP of women with a singleton breech fetus at or after 37(0/7) (259 days) weeks of gestation and normal amniotic fluid index. All 80 participants heard a 20-minute recorded intervention via head phones. Main outcome assessed was success rate of ECV. The intervention groups were compared with a control group with standard medical care alone (n = 122). Results. A total of 42 women, who received a hypnosis intervention prior to ECV, had a 40.5% (n = 17), successful ECV, whereas 38 women, who received NLP, had a 44.7% (n = 17) successful ECV (P > 0.05). The control group had similar patient characteristics compared to the intervention groups (P > 0.05). In the control group (n = 122) 27.3% (n = 33) had a statistically significant lower successful ECV procedure than NLP (P = 0.05) and hypnosis and NLP (P = 0.03). Conclusions. These findings suggest that prior clinical hypnosis and NLP have similar success rates of ECV procedures and are both superior to standard medical care alone.

  5. An Appraisal of Asia-Pacific Cities as Control and Command Centres Embedded in World City Network

    Directory of Open Access Journals (Sweden)

    Z. Li

    2017-08-01

    Full Text Available Since the globalization trend is proliferating at a staggering rate, world cities have emerged as the most dominant vanguard incorporated into global economy. Control and command function is one of the robust integral parts of world city formation, which is closely associated with the corporate headquarter status of some dominant multinational companies. Previous research works on this topic tend to concentrate on the Western Europe and North American arenas neglecting the Asia-Pacific region. Hence, the objective of this paper is to explore control and command functions of Asia-Pacific cities with reference to headquarters’ locations of multinational companies. The methodology will utilize the Forbes global 2000 dataset from the seminal study of GaWC research group, and apply the control and command center model and the interlocking city network model to discover the control and command index, as well as network connectivity of Asia-Pacific cities. Based upon the empirical study of this research, we could identify the hierarchical structure and spatial structure of Asia-Pacific world cities to emerge as some control and command centers embedded in world city network.

  6. European multi-centre case-control study on risk factors for rare cancers of unknown aetiology

    DEFF Research Database (Denmark)

    Lynge, Elsebeth; Afonso, Noemia; Kaerlev, Linda

    2005-01-01

    To search for occupational risk factors, we conducted a case-control study in nine European countries of cancers of the small intestine, male gall bladder, thymus, bone, male breast, melanoma of the eye, and mycosis fungoides. Recruitment was population based in Denmark, Latvia, France, Germany...... recruited 3374 population (61% interviewed) and 1284 colon cancer controls (86% interviewed). It was possible to undertake this complicated study across Europe, but we encountered three main problems. It was difficult to ensure complete case ascertainment, for population controls, we found a clear divide......, Italy, and Sweden, from hospital areas in Spain and Portugal, and from one United Kingdom (UK) hospital. We recruited 1457 cases (84% interviewed). Numbers identified corresponded to those in the EUROCIM database for Denmark, but were below those observed for France, Italy and Sweden in the database. We...

  7. Low social interactions in eating disorder patients in childhood and adulthood: a multi-centre European case control study.

    Science.gov (United States)

    Krug, Isabel; Penelo, Eva; Fernandez-Aranda, Fernando; Anderluh, Marija; Bellodi, Laura; Cellini, Elena; di Bernardo, Milena; Granero, Roser; Karwautz, Andreas; Nacmias, Benedetta; Ricca, Valdo; Sorbi, Sandro; Tchanturia, Kate; Wagner, Gudrun; Collier, David; Treasure, Janet

    2013-01-01

    The objective of this article was to examine lifestyle behaviours in eating disorder (ED) patients and healthy controls. A total of 801 ED patients and 727 healthy controls from five European countries completed the questions related to lifestyle behaviours of the Cross-Cultural Questionnaire (CCQ). For children, the ED sample exhibited more solitary activities (rigorously doing homework [psocializing with friends [pgroup and this continued in adulthood. There were minimal differences across ED sub-diagnoses and various cross-cultural differences emerged. Reduced social activities may be an important risk and maintaining factor for ED symptomatology.

  8. Cibola flight experiment satellite

    Science.gov (United States)

    Davies, P.; Liddle, Doug; Paffett, John; Sweeting, Martin; Curiel, A.; Sun, Wei; Eves, Stuart

    2004-11-01

    In order to achieve an "economy of scale" with respect to payload capacity the major trend in telecommunications satellites is for larger and larger platforms. With these large platforms the level of integration between platform and payload is increasing leading to longer delivery schedules. The typical lifecycle for procurement of these large telecommunications satellites is now 3-6 years depending on the level of non-recurring engineering needed. Surrey Satellite Technology Ltd (SSTL) has designed a low-cost platform aimed at telecommunications and navigation applications. SSTL's Geostationary Minisatellite Platform (GMP) is a new entrant addressing the lower end of the market with payloads up to 250kg requiring less than 1.5 kW power. The British National Space Centre through the MOSAIC Small Satellite Initiative supported the development of GMP. The main design goals for GMP are low-cost for the complete mission including launch and operations and a platform allowing flexible payload accommodation. GMP is specifically designed to allow rapid development and deployment with schedules typically between 1 and 2 years from contract signature to flight readiness. GMP achieves these aims by a modular design where the level of integration between the platform and payload is low. The modular design decomposes the satellite into three major components - the propulsion bay, the avionics bay and the payload module. Both the propulsion and avionics bays are reusable, largely unchanged, and independent of the payload configuration. Such a design means that SSTL or a 3rd party manufacturer can manufacture the payload in parallel to the platform with integration taking place quite late in the schedule. In July 2003 SSTL signed a contract for ESA's first Galileo navigation satellite known as GSTBV2/A. The satellite is based on GMP and ESA plan to launch it into a MEO orbit late in 2005. The second flight of GMP is likely to be in 2006 carrying a geostationary payload

  9. Experiences and Lessons Learnt with Collaborative e-Research Infrastructure and the application of Identity Management and Access Control for the Centre for Environmental Data Analysis

    Science.gov (United States)

    Kershaw, P.

    2016-12-01

    CEDA, the Centre for Environmental Data Analysis, hosts a range of services on behalf of NERC (Natural Environment Research Council) for the UK environmental sciences community and its work with international partners. It is host to four data centres covering atmospheric science, earth observation, climate and space data domain areas. It holds this data on behalf of a number of different providers each with their own data policies which has thus required the development of a comprehensive system to manage access. With the advent of CMIP5, CEDA committed to be one of a number of centres to host the climate model outputs and make them available through the Earth System Grid Federation, a globally distributed software infrastructure developed for this purpose. From the outset, a means for restricting access to datasets was required, necessitating the development a federated system for authentication and authorisation so that access to data could be managed across multiple providers around the world. From 2012, CEDA has seen a further evolution with the development of JASMIN, a multi-petabyte data analysis facility. Hosted alongside the CEDA archive, it provides a range of services for users including a batch compute cluster, group workspaces and a community cloud. This has required significant changes and enhancements to the access control system. In common with many other examples in the research community, the experiences of the above underline the difficulties of developing collaborative e-Research infrastructures. Drawing from these there are some recurring themes: Clear requirements need to be established at the outset recognising that implementing strict access policies can incur additional development and administrative overhead. An appropriate balance is needed between ease of access desired by end users and metrics and monitoring required by resource providers. The major technical challenge is not with security technologies themselves but their effective

  10. Geostationary satellites collocation

    CERN Document Server

    Li, Hengnian

    2014-01-01

    Geostationary Satellites Collocation aims to find solutions for deploying a safe and reliable collocation control. Focusing on the orbital perturbation analysis, the mathematical foundations for orbit and control of the geostationary satellite are summarized. The mathematical and physical principle of orbital maneuver and collocation strategies for multi geostationary satellites sharing with the same dead band is also stressed. Moreover, the book presents some applications using the above algorithms and mathematical models to help readers master the corrective method for planning station keeping maneuvers. Engineers and scientists in the fields of aerospace technology and space science can benefit from this book. Hengnian Li is the Deputy Director of State Key Laboratory of Astronautic Dynamics, China.

  11. Intensity modulated radiation therapy: Analysis of patient specific quality control results, experience of Rene-Gauducheau Centre

    International Nuclear Information System (INIS)

    Chiavassa, S.; Brunet, G.; Gaudaire, S.; Munos-Llagostera, C.; Delpon, G.; Lisbona, A.

    2011-01-01

    Purpose. - Systematic verifications of patient's specific intensity-modulated radiation treatments are usually performed with absolute and relative measurements. The results constitute a database which allows the identification of potential systematic errors. Material and methods. - We analyzed 1270 beams distributed in 232 treatment plans. Step-and-shoot intensity-modulated radiation treatments were performed with a Clinac (6 and 23 MV) and sliding window intensity-modulated radiation treatments with a Novalis (6 MV). Results. - The distributions obtained do not show systematic error and all the control meet specified tolerances. Conclusion. - These results allow us to reduce controls specific patients for treatments performed under identical conditions (location, optimization and segmentation parameters of treatment planning system, etc.). (authors)

  12. Pilates based core stability training in ambulant individuals with multiple sclerosis: protocol for a multi-centre randomised controlled trial

    OpenAIRE

    Freeman, Jennifer; Fox, Esther; Gear, Margaret; Hough, Alan

    2012-01-01

    Abstract Background People with Multiple Sclerosis (MS) frequently experience balance and mobility impairments, including reduced trunk stability. Pilates-based core stability training, which is aimed at improving control of the body's stabilising muscles, is popular as a form of exercise with people with MS and therapists. A replicated single case series study facilitated by the Therapists in MS Group in the United Kingdom (UK) provides preliminary evidence that this approach can improve bal...

  13. Spanish Earth Observation Satellite System

    Science.gov (United States)

    Borges, A.; Cerezo, F.; Fernandez, M.; Lomba, J.; Lopez, M.; Moreno, J.; Neira, A.; Quintana, C.; Torres, J.; Trigo, R.; Urena, J.; Vega, E.; Vez, E.

    2010-12-01

    The Spanish Ministry of Industry, Tourism and Trade (MITyC) and the Ministry of Defense (MoD) signed an agreement in 2007 for the development of a "Spanish Earth Observation Satellite System" based, in first instance, on two satellites: a high resolution optical satellite, called SEOSAT/Ingenio, and a radar satellite based on SAR technology, called SEOSAR/Paz. SEOSAT/Ingenio is managed by MITyC through the Centre for the Development of Industrial Technology (CDTI), with technical and contractual support from the European Space Agency (ESA). HISDESA T together with the Spanish Instituto Nacional de Técnica Aeroespacial (INTA, National Institute for Aerospace Technology) will be responsible for the in-orbit operation and the commercial operation of both satellites, and for the technical management of SEOSAR/Paz on behalf of the MoD. In both cases EADS CASA Espacio (ECE) is the prime contractor leading the industrial consortia. The ground segment development will be assigned to a Spanish consortium. This system is the most important contribution of Spain to the European Programme Global Monitoring for Environment and Security, GMES. This paper presents the Spanish Earth Observation Satellite System focusing on SEOSA T/Ingenio Programme and with special emphasis in the potential contribution to the ESA Third Party Missions Programme and to the Global Monitoring for Environment and Security initiative (GMES) Data Access.

  14. DUBNA-GRAN SASSO: Satellite computer link

    International Nuclear Information System (INIS)

    Anon.

    1994-01-01

    In April a 64 kbit/s computer communication link was set up between the Joint Institute for Nuclear Research (JINR), Dubna (Russia) and Gran Sasso (Italy) Laboratories via nearby ground satellite stations using the INTELSAT V satellite. Previously the international community of Dubna's experimentalists and theorists (high energy physics, condensed matter physics, low energy nuclear and neutron physics, accelerator and applied nuclear physics) had no effective computer links with scientific centres worldwide

  15. Launching the First Indian Satellite

    Indian Academy of Sciences (India)

    materials and chemicals, rocket propulsion, satellite technology, control and guidance system, etc. ... entire country, especially the rural areas, and in the survey and management of natural resources. Listeners are no .... satellite will store the information over a longer period and then on command from the ground station at ...

  16. Oxygen titration after resuscitation from out-of-hospital cardiac arrest: a multi-centre, randomised controlled pilot study (the EXACT pilot trial).

    Science.gov (United States)

    Bray, Janet E; Hein, Cindy; Smith, Karen; Stephenson, Michael; Grantham, Hugh; Finn, Judith; Stub, Dion; Cameron, Peter

    2018-04-20

    Recent studies suggest the administration of 100% oxygen to hyperoxic levels following return-of-spontaneous-circulation (ROSC) post-cardiac arrest may be harmful. However, the feasibility and safety of oxygen titration in the prehospital setting is unknown. We conducted a multi-centre, phase-2 study testing whether prehospital titration of oxygen results in an equivalent number of patients arriving at hospital with oxygen saturations SpO2 ≥ 94%. We enrolled unconscious adults with: sustained ROSC; initial shockable rhythm; an advanced airway; and an SpO2 ≥ 95%. Initially (Sept 2015-March 2016) patients were randomised 1:1 to either 2 litres/minute (L/min) oxygen (titrated) or >10 L/min oxygen (control) via a bag-valve reservoir. However, one site experienced a high number of desaturations (SpO2 titrated arm and this arm was changed (April 2016) to an initial reduction of oxygen to 4 L/min then, if tolerated, to 2 L/min, and the desaturation limit was decreased to titrated (n = 37: 2L/min = 20 and 2-4 L/min = 17) oxygen or control (n = 24). Patients allocated to titrated oxygen were more likely to desaturate compared to controls ((SpO2 titrated: 90% vs. control: 100%) and all patients had a SpO2 ≥ 90%. One patient (control) re-arrested. Survival to hospital discharge was similar. Oxygen titration post-ROSC is feasible in the prehospital environment, but incremental titration commencing at 4L/min oxygen flow may be needed to maintain an oxygen saturation >90% (NCT02499042). Copyright © 2018. Published by Elsevier B.V.

  17. Control de eficiencia en accionamiento de bombas centrífugas para transporte de hidromezclas usando lógica difusa

    Directory of Open Access Journals (Sweden)

    Luis D Rojas Purón

    2011-02-01

    Full Text Available Se presenta un algoritmo de control difuso que tiene en cuenta las especificidades de los subsistemaseléctrico y mecánico del accionamiento. Es de interés un bloque compensador del torque electromagnéticoque mejora el trabajo del controlador difuso ante los fenómenos de cavitación que ocasiona pulsacionesdel momento y la resonancia mecánica que pueden aparecer durante el trabajo de la bomba centrífuga.Se muestran resultados experimentales de accionamientos de la planta de lixiviación de la empresaComandante Ernesto Che Guevara de Moa, con un efecto económico de aproximadamente 262 000 USDanuales por energía dejada de consumir en forma de pérdidas con el uso del controlador operando adiferentes niveles de cargas mecánicas, y que sirve para ser utilizado en accionamientos de bombas delas plantas metalúrgicas de Moa y Nicaro.  A fuzzy logic control algorithm offers the specificities of the electric subsystem and mechanic of theoperations. It is of interest a block compensator of the electromagnetic torque that improves the work ofthe fuzzy controller's before the cavitation phenomena that causes pulsations of the torque and themechanical resonance that can appear during the operation of the centrifugal pumps. Experimentalresults are shown with the controller operating at the leaching plant of the Ernesto Che Guevara Corporation,Moa for an economic effect of 262 000 USD per year. which most of the unused energy in form of losses,when the controller works to different mechanical loads and that it is good to be used in operations ofpumps of the metallurgical plants of Moa and Nicaro.

  18. MicroRNA-133 Controls Brown Adipose Determination in Skeletal Muscle Satellite Cells by Targeting Prdm16

    DEFF Research Database (Denmark)

    Yin, Hang; Pasut, Alessandra; Soleimani, Vahab D

    2013-01-01

    Brown adipose tissue (BAT) is an energy-dispensing thermogenic tissue that plays an important role in balancing energy metabolism. Lineage-tracing experiments indicate that brown adipocytes are derived from myogenic progenitors during embryonic development. However, adult skeletal muscle stem cells...... (satellite cells) have long been considered uniformly determined toward the myogenic lineage. Here, we report that adult satellite cells give rise to brown adipocytes and that microRNA-133 regulates the choice between myogenic and brown adipose determination by targeting the 3'UTR of Prdm16. Antagonism...... of microRNA-133 during muscle regeneration increases uncoupled respiration, glucose uptake, and thermogenesis in local treated muscle and augments whole-body energy expenditure, improves glucose tolerance, and impedes the development of diet-induced obesity. Finally, we demonstrate that miR-133 levels...

  19. Effects of a partially supervised conditioning programme in cystic fibrosis: an international multi-centre randomised controlled trial (ACTIVATE-CF): study protocol.

    Science.gov (United States)

    Hebestreit, Helge; Lands, Larry C; Alarie, Nancy; Schaeff, Jonathan; Karila, Chantal; Orenstein, David M; Urquhart, Don S; Hulzebos, Erik H J; Stein, Lothar; Schindler, Christian; Kriemler, Susi; Radtke, Thomas

    2018-02-08

    Physical activity (PA) and exercise have become an accepted and valued component of cystic fibrosis (CF) care. Regular PA and exercise can positively impact pulmonary function, improve physical fitness, and enhance health-related quality of life (HRQoL). However, motivating people to be more active is challenging. Supervised exercise programs are expensive and labour intensive, and adherence falls off significantly once supervision ends. Unsupervised or partially supervised programs are less costly and more flexible, but compliance can be more problematic. The primary objective of this study is to evaluate the effects of a partially supervised exercise intervention along with regular motivation on forced expiratory volume in 1 s (FEV 1 ) at 6 months in a large international group of CF patients. Secondary endpoints include patient reported HRQoL, as well as levels of anxiety and depression, and control of blood sugar. It is planned that a total of 292 patients with CF 12 years and older with a FEV 1  ≥ 35% predicted shall be randomised. Following baseline assessments (2 visits) patients are randomised into an intervention and a control group. Thereafter, they will be seen every 3 months for assessments in their centre for one year (4 follow-up visits). Along with individual counselling to increase vigorous PA by at least 3 h per week on each clinic visit, the intervention group documents daily PA and inactivity time and receives a step counter to record their progress within a web-based diary. They also receive monthly phone calls from the study staff during the first 6 months of the study. After 6 months, they continue with the step counter and web-based programme for a further 6 months. The control group receives standard care and keeps their PA level constant during the study period. Thereafter, they receive the intervention as well. This is the first large, international multi-centre study to investigate the effects of a PA intervention in CF with

  20. Attitude Control and Orbital Dynamics Challenges of Removing the First 3-Axis Stabilized Tracking and Data Relay Satellite from the Geosynchronous ARC

    Science.gov (United States)

    Benet, Charles A.; Hofman, Henry; Williams, Thomas E.; Olney, Dave; Zaleski, Ronald

    2011-01-01

    Launched on April 4, 1983 onboard STS 6 (Space Shuttle Challenger), the First Tracking and Data Relay Satellite (TDRS 1) was retired above the Geosynchronous Orbit (GEO) on June 27, 2010 after having provided real-time communications with a variety of low-orbiting spacecraft over a 26-year period. To meet NASA requirements limiting orbital debris 1, a team of experts was assembled to conduct an End-Of-Mission (EOM) procedure to raise the satellite 350 km above the GEO orbit. Following the orbit raising via conventional station change maneuvers, the team was confronted with having to deplete the remaining propellant and passivate all energy storage or generation sources. To accomplish these tasks within the time window, communications (telemetry and control links), electrical power, propulsion, and thermal constraints, a spacecraft originally designed as a three-axis stabilized satellite was turned into a spinner. This paper (a companion paper to Innovative Approach Enabled the Retirement of TDRS 1, paper # 1699, IEEE 2011 Aerospace Conference, March 5-12, 2011 sup 2) focuses on the challenges of maintaining an acceptable spinning dynamics, while repetitively firing thrusters. Also addressed are the effects of thruster firings on the orbit characteristics and how they were mitigated by a careful scheduling of the fuel depletion operations. Periodic thruster firings for spin rate adjustment, nutation damping, and precession of the momentum vector were also required in order to maintain effective communications with the satellite. All operations were thoroughly rehearsed and supported by simulations thus lending a high level of confidence in meeting the NASA EOM goals.

  1. CoDuSe group exercise programme improves balance and reduces falls in people with multiple sclerosis: A multi-centre, randomized, controlled pilot study.

    Science.gov (United States)

    Carling, Anna; Forsberg, Anette; Gunnarsson, Martin; Nilsagård, Ylva

    2017-09-01

    Imbalance leading to falls is common in people with multiple sclerosis (PwMS). To evaluate the effects of a balance group exercise programme (CoDuSe) on balance and walking in PwMS (Expanded Disability Status Scale, 4.0-7.5). A multi-centre, randomized, controlled single-blinded pilot study with random allocation to early or late start of exercise, with the latter group serving as control group for the physical function measures. In total, 14 supervised 60-minute exercise sessions were delivered over 7 weeks. Pretest-posttest analyses were conducted for self-reported near falls and falls in the group starting late. Primary outcome was Berg Balance Scale (BBS). A total of 51 participants were initially enrolled; three were lost to follow-up. Post-intervention, the exercise group showed statistically significant improvement ( p = 0.015) in BBS and borderline significant improvement in MS Walking Scale ( p = 0.051), both with large effect sizes (3.66; -2.89). No other significant differences were found between groups. In the group starting late, numbers of falls and near falls were statistically significantly reduced after exercise compared to before ( p balance and reduced perceived walking limitations, compared to no exercise. The intervention reduced falls and near falls frequency.

  2. Feasibility of a patient-centred nutrition intervention to improve oral intakes of patients at risk of pressure ulcer: a pilot randomised control trial.

    Science.gov (United States)

    Roberts, Shelley; Desbrow, Ben; Chaboyer, Wendy

    2016-06-01

    Nutrition is important for pressure ulcer prevention. This randomised control pilot study assessed the feasibility of conducting a larger trial to test the effectiveness of a patient-centred intervention for improving the dietary intakes of patients at risk of pressure ulcer in hospital. A 3-day intervention targeting patients at risk of pressure ulcer was developed, based on three main foundations: patient education, patient participation and guided goal setting. The intervention was piloted in three wards in a metropolitan hospital in Queensland, Australia. Participants were randomised into control or intervention groups and had their oral intakes monitored. A subset of intervention patients was interviewed on their perceptions of the intervention. Feasibility was tested against three criteria: ≥75% recruitment; ≥80% retention; and ≥80% intervention fidelity. Secondary outcomes related to effects on energy and protein intakes. Eighty patients participated in the study and 66 were included in final analysis. The recruitment rate was 82%, retention rate was 88%, and 100% of intervention patients received the intervention. Patients viewed the intervention as motivating and met significantly more of their estimated energy and protein requirements over time. This pilot study indicates that the intervention is feasible and acceptable by patients at risk of pressure ulcer. A larger trial is needed to confirm the effectiveness of the intervention in the clinical setting. © 2015 Nordic College of Caring Science.

  3. Satellite Radio

    Indian Academy of Sciences (India)

    Satellites have been a highly effective platform for multi- form broadcasts. This has led to a ... diversity offormats, languages, genre, and a universal reach that cannot be met by .... programs can be delivered to whom it is intended. In the case of.

  4. Design of Lamifuse: a randomised, multi-centre controlled trial comparing laminectomy without or with dorsal fusion for cervical myeloradiculopathy

    Directory of Open Access Journals (Sweden)

    Grotenhuis J André

    2007-11-01

    Full Text Available Abstract Background laminectomy is a valuable surgical treatment for some patients with a cervical radiculomyelopathy due to cervical spinal stenosis. More recently attention has been given to motion of the spinal cord over spondylotic spurs as a cause of myelopathic changes. Immobilisation by fusion could have a positive effect on the recovery of myelopathic signs or changes. This has never been investigated in a prospective, randomised trial. Lamifuse is an acronyme for laminectomy and fusion. Methods/Design Lamifuse is a multicentre, randomised controlled trial comparing laminectomy with and without fusion in patients with a symptomatic cervical canal stenosis. The study population will be enrolled from patients that are 60 years or older with myelopathic signs and/or symptoms due to a cervical canal stenosis. A kyphotis shape of the cervical spine is an exclusion criterium. Each treatment arm needs 30 patients. Discussion This study will contribute to the discussion whether additional fusion after a cervical laminectomy results in a better clinical outcome. ISRCT number ISRCTN72800446

  5. Evaluation of the flow forces on an open centre directional control valve by means of a computational fluid dynamic analysis

    International Nuclear Information System (INIS)

    Amirante, R.; Del Vescovo, G.; Lippolis, A.

    2006-01-01

    The aim of the present paper is the evaluation of the driving forces acting on a 4/3 hydraulic open center directional control valve spool by means of a complete numerical analysis. In a previous paper by the same authors, the valve was inserted in a closed hydraulic circuit and was tested with different pump flow rate values to obtain experimental results about the driving forces. The experimental results are used in this paper to evaluate and validate the numerical analysis of the valve. The obtained numerical results show important differences between an open center valve and a closed center one, the latter being extensively analyzed in the literature. The numerical analysis is performed by using the commercial code 'Fluent', and the numerical results show the complete flow field inside the valve. The aim of this analysis is to evaluate the valve fluid dynamic performance, exploiting computational fluid dynamics (CFD) techniques, in order to give the reliable indications needed to define the valve design criteria and avoid expensive experimental tests

  6. Radioecological investigations in the environment of the Research Centre Seibersdorf and of a comparable control biotop in Klosterneuburg

    International Nuclear Information System (INIS)

    Tatzber, F.; Irlweck, K.; Sorantin, H.; Schaller, F.

    1981-09-01

    Investigations concerning the distribution of radionuclides were carried out on the area and the closer surroundings of the Seibersdorf Research Center and a comparable control biotop in Klosterneuburg. No environmental encroachment on the biosphere could be shown even after 20 years of operation of the research plant (10MW). Gammaspectrometric measurements and radiochemical analysis of various animal samples proved that contaminations found were in most cases due to fallout from atmospheric nuclear weapon testing in the early sixties. Only single surveys give hints of small quantities of 60-Co being spread. Maximum concentrations of 60-Co 0.5 pCi/g dry weight were found in those samples, which is about the value of fallout concentration of radiocaesium and may be neglected from the point of view of health physics. Additionally soil radioactivity investigations were done to estimate the part of total radioactivity which is spread by animals. Results showed that only 10sup-4 of the total quantity of fallout deposited radionuclides present in a soil layer of some square meters and a depth of 10 cm are spread by the investigated animals. (author) [de

  7. A randomized controlled trial to evaluate utilization of physical activity recommendations among patients of cardiovascular healthcare centres in Eastern Slovakia: study design and rationale of the AWATAR study.

    Science.gov (United States)

    Zelko, Aurel; Bukova, Alena; Kolarcik, Peter; Bakalar, Peter; Majercak, Ivan; Potocnikova, Jana; Reijneveld, Sijmen A; van Dijk, Jitse P

    2018-04-04

    Guidelines on modifiable risk factors regarding cardiological patients are poorly implemented in clinical practice perhaps due to low health literacy. Several digital tools for improving lifestyle and behavioural intervention were developed. Our primary aim is to evaluate the effectiveness of a digital exercise prescription tool on the adherence to physical activity recommendations among patients with cardiovascular diseases. A randomized controlled trial will be realized in cooperation with Cardiovascular Health Centres in Eastern Slovakia. Patients recruited through their cardiologists, will be randomised at 1:1 ratio to the three-months' experimental condition or control condition. The experimental group will receive standard lifestyle consultation leading to individually optimized prescription of physical activity. The control group will receive standard, usual-cardio-care lifestyle counselling, also in the domain of physical activity. The digital system will be used for optimized exercise prescription. The primary outcome is a change in the patient's adherence to exercise recommendations. Data will be collected in both groups prior to consultation and after 3 months. This study protocol presents background and design of a randomized control trial to investigate the effectiveness of a digital system-provide exercise prescription tool on the adherence to physical activity recommendations. An optimized exercise prescription that better reflects patient's diagnosis, comorbidities and medication can have a significant impact on secondary prevention of cardiovascular disease. This trial can provide important evidence about the effectiveness of digital exercise guidance in everyday practice of cardiovascular healthcare. The study was registered on 1st November, 2017 and is available online at ClinicalTrials.gov (ID: NCT03329053 ).

  8. Gatifloxacin versus ceftriaxone for uncomplicated enteric fever in Nepal: an open-label, two-centre, randomised controlled trial.

    Science.gov (United States)

    Arjyal, Amit; Basnyat, Buddha; Nhan, Ho Thi; Koirala, Samir; Giri, Abhishek; Joshi, Niva; Shakya, Mila; Pathak, Kamal Raj; Mahat, Saruna Pathak; Prajapati, Shanti Pradhan; Adhikari, Nabin; Thapa, Rajkumar; Merson, Laura; Gajurel, Damodar; Lamsal, Kamal; Lamsal, Dinesh; Yadav, Bharat Kumar; Shah, Ganesh; Shrestha, Poojan; Dongol, Sabina; Karkey, Abhilasha; Thompson, Corinne N; Thieu, Nga Tran Vu; Thanh, Duy Pham; Baker, Stephen; Thwaites, Guy E; Wolbers, Marcel; Dolecek, Christiane

    2016-05-01

    Because treatment with third-generation cephalosporins is associated with slow clinical improvement and high relapse burden for enteric fever, whereas the fluoroquinolone gatifloxacin is associated with rapid fever clearance and low relapse burden, we postulated that gatifloxacin would be superior to the cephalosporin ceftriaxone in treating enteric fever. We did an open-label, randomised, controlled, superiority trial at two hospitals in the Kathmandu valley, Nepal. Eligible participants were children (aged 2-13 years) and adult (aged 14-45 years) with criteria for suspected enteric fever (body temperature ≥38·0°C for ≥4 days without a focus of infection). We randomly assigned eligible patients (1:1) without stratification to 7 days of either oral gatifloxacin (10 mg/kg per day) or intravenous ceftriaxone (60 mg/kg up to 2 g per day for patients aged 2-13 years, or 2 g per day for patients aged ≥14 years). The randomisation list was computer-generated using blocks of four and six. The primary outcome was a composite of treatment failure, defined as the occurrence of at least one of the following: fever clearance time of more than 7 days after treatment initiation; the need for rescue treatment on day 8; microbiological failure (ie, blood cultures positive for Salmonella enterica serotype Typhi, or Paratyphi A, B, or C) on day 8; or relapse or disease-related complications within 28 days of treatment initiation. We did the analyses in the modified intention-to-treat population, and subpopulations with either confirmed blood-culture positivity, or blood-culture negativity. The trial was powered to detect an increase of 20% in the risk of failure. This trial was registered at ClinicalTrials.gov, number NCT01421693, and is now closed. Between Sept 18, 2011, and July 14, 2014, we screened 725 patients for eligibility. On July 14, 2014, the trial was stopped early by the data safety and monitoring board because S Typhi strains with high-level resistance to

  9. Community-centred eco-bio-social approach to control dengue vectors: an intervention study from Myanmar.

    Science.gov (United States)

    Wai, Khin Thet; Htun, Pe Than; Oo, Tin; Myint, Hla; Lin, Zaw; Kroeger, Axel; Sommerfeld, Johannes; Petzold, Max

    2012-12-01

    To build up and analyse the feasibility, process, and effectiveness of a partnership-driven ecosystem management intervention in reducing dengue vector breeding and constructing sustainable partnerships among multiple stakeholders. A community-based intervention study was conducted from May 2009 to January 2010 in Yangon city. Six high-risk and six low-risk clusters were randomized and allocated as intervention and routine service areas, respectively. For each cluster, 100 households were covered. Bi-monthly entomological evaluations (i.e. larval and pupal surveys) and household acceptability surveys at the end of 6-month intervention period were conducted, supplemented by qualitative evaluations. Intervention description: The strategies included eco-friendly multi-stakeholder partner groups (Thingaha) and ward-based volunteers, informed decision-making of householders, followed by integrated vector management approach. Pupae per person index (PPI) decreased at the last evaluation by 5·7% (0·35-0·33) in high-risk clusters. But in low-risk clusters, PPI remarkably decreased by 63·6% (0·33-0·12). In routine service area, PPI also decreased due to availability of Temephos after Cyclone Nargis. As for total number of pupae in all containers, when compared to evaluation 1, there was a reduction of 18·6% in evaluation 2 and 44·1% in evaluation 3 in intervention area. However, in routine service area, more reduction was observed. All intervention tools were found as acceptable, being feasible to implement by multi-stakeholder partner groups. The efficacy of community-controlled partnership-driven interventions was found to be superior to the vertical approach in terms of sustainability and community empowerment.

  10. Financial considerations in the conduct of multi-centre randomised controlled trials: evidence from a qualitative study.

    Science.gov (United States)

    Snowdon, Claire; Elbourne, Diana R; Garcia, Jo; Campbell, Marion K; Entwistle, Vikki A; Francis, David; Grant, Adrian M; Knight, Rosemary C; McDonald, Alison M; Roberts, Ian

    2006-12-21

    Securing and managing finances for multicentre randomised controlled trials is a highly complex activity which is rarely considered in the research literature. This paper describes the process of financial negotiation and the impact of financial considerations in four UK multicentre trials. These trials had met, or were on schedule to meet, recruitment targets agreed with their public-sector funders. The trials were considered within a larger study examining factors which might be associated with trial recruitment (STEPS). In-depth semi-structured telephone interviews were conducted in 2003-04 with 45 individuals with various responsibilities to one of the four trials. Interviewees were recruited through purposive and then snowball sampling. Interview transcripts were analysed with the assistance of the qualitative package Atlas-ti. The data suggest that the UK system of dividing funds into research, treatment and NHS support costs brought the trial teams into complicated negotiations with multiple funders. The divisions were somewhat malleable and the funding system was used differently in each trial. The fact that all funders had the potential to influence and shape the trials considered here was an important issue as the perspectives of applicants and funders could diverge. The extent and range of industry involvement in non-industry-led trials was striking. Three broad periods of financial work (foundation, maintenance, and resourcing completion) were identified. From development to completion of a trial, the trialists had to be resourceful and flexible, adapting to changing internal and external circumstances. In each period, trialists and collaborators could face changing costs and challenges. Each trial extended the recruitment period; three required funding extensions from MRC or HTA. This study highlights complex financial aspects of planning and conducting trials, especially where multiple funders are involved. Recognition of the importance of financial

  11. Financial considerations in the conduct of multi-centre randomised controlled trials: evidence from a qualitative study

    Directory of Open Access Journals (Sweden)

    Grant Adrian M

    2006-12-01

    Full Text Available Abstract Background Securing and managing finances for multicentre randomised controlled trials is a highly complex activity which is rarely considered in the research literature. This paper describes the process of financial negotiation and the impact of financial considerations in four UK multicentre trials. These trials had met, or were on schedule to meet, recruitment targets agreed with their public-sector funders. The trials were considered within a larger study examining factors which might be associated with trial recruitment (STEPS. Methods In-depth semi-structured telephone interviews were conducted in 2003–04 with 45 individuals with various responsibilities to one of the four trials. Interviewees were recruited through purposive and then snowball sampling. Interview transcripts were analysed with the assistance of the qualitative package Atlas-ti. Results The data suggest that the UK system of dividing funds into research, treatment and NHS support costs brought the trial teams into complicated negotiations with multiple funders. The divisions were somewhat malleable and the funding system was used differently in each trial. The fact that all funders had the potential to influence and shape the trials considered here was an important issue as the perspectives of applicants and funders could diverge. The extent and range of industry involvement in non-industry-led trials was striking. Three broad periods of financial work (foundation, maintenance, and resourcing completion were identified. From development to completion of a trial, the trialists had to be resourceful and flexible, adapting to changing internal and external circumstances. In each period, trialists and collaborators could face changing costs and challenges. Each trial extended the recruitment period; three required funding extensions from MRC or HTA. Conclusion This study highlights complex financial aspects of planning and conducting trials, especially where multiple

  12. The effects of a new mouthrinse containing chlorhexidine, cetylpyridinium chloride and zinc lactate on the microflora of oral halitosis patients : a dual-centre, double-blind placebo-controlled study

    NARCIS (Netherlands)

    Roldan, S; Winkel, EG; Herrera, D; Sanz, M; Van Winkelhoff, AJ

    Aim: This study evaluated the microbial effects of a newly formulated mouthwash (Halita((R)) ) on oral halitosis patients. Methods: Forty subjects were included in this dual-centre, double-blind, placebo-controlled parallel study. Inclusion and exclusion criteria were used to select patients. At

  13. Effect of the daily consumption of protein enriched bread and protein enriched drinking yoghurt on the total protein intake in older adults in a rehabilitation centre: a single blind randomised controlled trial

    NARCIS (Netherlands)

    Til, van A.J.; Naumann, E.; Cox-Claessens, I.J.H.M.; Kremer, S.; Boelsma, E.; Schueren, van der D.E.

    2015-01-01

    Objectives To investigate the effects of protein enriched bread and drinking yoghurt, substituting regular products, on the total protein intake and the distribution of protein intake over the day in older adults. Design A single blind randomised controlled trial. Setting Rehabilitation centre.

  14. Human-centred Governance

    DEFF Research Database (Denmark)

    Bason, Christian

    2017-01-01

    Design approaches are now being applied all over the world as a powerful approach to innovating public policies and services. Christian Bason, author of Leading public design: Discovering human-centred governance, argues that by bringing design methods into play, public managers can lead change...... with citizens at the centre, and discover a new model for steering public organisations: human-centred governance....

  15. The Search for Centre

    Science.gov (United States)

    Nunes, April

    2006-01-01

    This paper acknowledges the importance of a dancer's centre but likewise highlights the problematic nature of the communication of this concept from dance teacher to student. After a brief introduction of orthodox approaches in finding centre, this paper suggests a method of locating centre through the ancient somatic technique.

  16. Protocol for the combined immunosuppression & radiotherapy in thyroid eye disease (CIRTED trial: A multi-centre, double-masked, factorial randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Kingston Laura

    2008-01-01

    Full Text Available Abstract Background Medical management of thyroid eye disease remains controversial due to a paucity of high quality evidence on long-term treatment outcomes. Glucocorticoids are known to be effective initially but have significant side-effects with long-term use and recrudescence can occur on cessation. Current evidence is conflicting on the efficacy of radiotherapy and non-steroid systemic immunosuppression, and the majority of previous studies have been retrospective, uncontrolled, small or poorly designed. The Combined Immunosuppression and Radiotherapy in Thyroid Eye Disease (CIRTED trial was designed to investigate the efficacy of radiotherapy and azathioprine in combination with a standard course of oral prednisolone in patients with active thyroid eye disease. Methods/design Patients with active thyroid eye disease will be randomised to receive (i azathioprine or oral placebo and (ii radiotherapy or sham-radiotherapy in this multi-centre, factorial randomised control trial. The primary outcome is improvement in disease severity (assessed using a composite binary measure at 12 months and secondary end-points include quality of life scores and health economic measures. Discussion The CIRTED trial is the first study to evaluate the role of radiotherapy and azathioprine as part of a long-term, combination immunosuppressive treatment regime for Thyroid Eye Disease. It will provide evidence for the role of radiotherapy and prolonged immunosuppression in the management of this condition, as well as pilot data on their use in combination. We have paid particular attention in the trial design to establishing (a robust placebo controls and masking protocols which are effective and safe for both radiotherapy and the systemic administration of an antiproliferative drug; (b constructing effective inclusion and exclusion criteria to select for active disease; and (c selecting pragmatic outcome measures. Trial registration Current controlled trials

  17. Control options for communal energy turnaround by energy coordination centres. Investigation based on the Erzgebirge energy region; Steuerungsmoeglichkeiten der kommunalen Energiewende durch Energieleitstellen. Untersuchung anhand der Energieregion-Erzgebirge

    Energy Technology Data Exchange (ETDEWEB)

    Zuk, David

    2012-11-01

    The book investigates the role of energy coordination centres for communal energy turnaround. The investigations were carried out in the Erzgebirge energy region, which comprises 13 member communities. It was found that the influence of an energy coordination centre on a community is parallel to the community's awareness of the necessity of local energy turnaround measures. Energy control centres can sharpen this awareness of communities by outlining individual advantages of engagement with these issues and by making concrete suggestions for projects. Here, it becomes clear that communities will be more interested especially in bigger investment projects of an (external)financially strong investor. Most of the communities under investigation were in the range of 1,000 to 7,000 inhabitants; it must be assumed that in this case the opinions of the highest-ranked person of communal authority. This consideration should influence the scope of action of energy coordination centres. The example of a 'pioneering community' in the energy region showed that the consulting services of the energy coordination centre not only led to lower energy consumption (and, in consequence, lower energy expenses) on a medium-term basis but also helped to coordinate the activities of initiatives, e.g. initiatives promoting citizens-owned solar power stations. As the book shows, energy coordination centres take care of communities in general but are also actively supporting initiatives within the community and have a coordinating function when it comes to intercommunity projects. While energy coordination centres are not a 'heal-all' for implementation of the energy turnaround at community level or regional level, they must be viewed as a powerful instrument to achieve it. (orig.)

  18. Earth Observing System/Meteorological Satellite (EOS/METSAT). Advanced Microwave Sounding Unit-A (AMSU-A) Contamination Control Plan

    Science.gov (United States)

    Fay, M.

    1998-01-01

    This Contamination Control Plan is submitted in response the Contract Document requirements List (CDRL) 007 under contract NAS5-32314 for the Earth Observing System (EOS) Advanced Microwave Sounding Unit A (AMSU-A). In response to the CDRL instructions, this document defines the level of cleanliness and methods/procedures to be followed to achieve adequate cleanliness/contamination control, and defines the required approach to maintain cleanliness/contamination control through shipping, observatory integration, test, and flight. This plan is also applicable to the Meteorological Satellite (METSAT) except where requirements are identified as EOS-specific. This plan is based on two key factors: a. The EOS/METSAT AMSU-A Instruments are not highly contamination sensitive. b. Potential contamination of other EOS Instruments is a key concern as addressed in Section 9/0 of the Performance Assurance Requirements for EOS/METSAT Integrated Programs AMSU-A Instrument (MR) (NASA Specification S-480-79).

  19. Provision of oral hygiene services as a potential method for preventing periodontal disease and control hypertension and diabetes in a community health centre in Korea.

    Science.gov (United States)

    Kim, Nam-Hee; Lee, Ga-Yeong; Park, Su-Kyung; Kim, Yeun-Ju; Lee, Min-Young; Kim, Chun-Bae

    2018-05-01

    This study aimed to evaluate the effects of a community-based oral hygiene service on general and periodontal health indicators of patients with hypertension and type 2 diabetes mellitus visiting a community health centre in Korea. The study used a one-group pretest-posttest and interrupted time-series design. A total of 151 participants (45% male), with a mean age of 63 ± 8.4 years, were included in the study; these included patients with hypertension (62%), diabetes (12%) and both hypertension and diabetes (26%). Two dental hygienists dedicated 2 days per week to this project, providing oral hygiene services to 10-13 participants per day. Four oral hygiene service sessions were provided per patient. The objective oral hygiene status and subjective self-reported periodontal status were compared before and after the service. The changes in blood pressure and glycosylated haemoglobin levels were also assessed. A lower frequency of subjective swelling was reported at the fourth session (37.9%) compared to the first (55.6%) session. Further, significantly fewer cases of calculus and bleeding were observed (p hygiene services provided by dental hygienists can promote objective oral hygiene and subjective periodontal status in the local community, and may help in the control of hypertension and diabetes. © 2017 John Wiley & Sons Ltd.

  20. Intensive client-centred occupational therapy in the home improves older adults' occupational performance. Results from a Danish randomized controlled trial.

    Science.gov (United States)

    Nielsen, Tove Lise; Andersen, Niels Trolle; Petersen, Kirsten Schultz; Polatajko, Helene; Nielsen, Claus Vinther

    2018-01-12

    There is growing interest in enabling older adults' occupational performance. We tested whether 11 weeks of intensive client-centred occupational therapy (ICC-OT) was superior to usual practice in improving the occupational performance of home-dwelling older adults. An assessor-masked randomized controlled trial among adults 60 + with chronic health issues, who received or applied for homecare services. Recruitment took place September 2012 to April 2014. All participants received practical and personal assistance and meal delivery as needed. In addition, they were randomized to receive either a maximum 22 sessions of occupation-based ICC-OT (N = 59) or to receive usual practice with a maximum three sessions of occupational therapy (N = 60). The primary outcome was self-rated occupational performance assessed with the Canadian Occupational Performance Measure (COPM). No important adverse events occurred. ICC-OT was accepted by 46 participants (88%), usual practice by 60 (100%). After 3 months, the ICC-OT-group had improved 1.86 points on COPM performance; the Usual-Practice group had improved 0.61 points. The between-group difference was statistically significant (95% confidence interval 0.50 to 2.02), t-test: p = 0.001. ICC-OT improved older adults' occupational performance more effectively than usual practice. This result may benefit older adults and support programmatic changes.

  1. The European Centre for Disease Prevention and Control (ECDC) pilot point prevalence survey of healthcare-associated infections and antimicrobial use.

    Science.gov (United States)

    Zarb, P; Coignard, B; Griskeviciene, J; Muller, A; Vankerckhoven, V; Weist, K; Goossens, Mm; Vaerenberg, S; Hopkins, S; Catry, B; Monnet, Dl; Goossens, H; Suetens, C

    2012-11-15

    A standardised methodology for a combined point prevalence survey (PPS) on healthcare-associated infections (HAIs) and antimicrobial use in European acute care hospitals developed by the European Centre for Disease Prevention and Control was piloted across Europe. Variables were collected at national, hospital and patient level in 66 hospitals from 23 countries. A patient-based and a unit-based protocol were available. Feasibility was assessed via national and hospital questionnaires. Of 19,888 surveyed patients, 7.1% had an HAI and 34.6% were receiving at least one antimicrobial agent. Prevalence results were highest in intensive care units, with 28.1% patients with HAI, and 61.4% patients with antimicrobial use. Pneumonia and other lower respiratory tract infections (2.0% of patients; 95% confidence interval (CI): 1.8–2.2%) represented the most common type (25.7%) of HAI. Surgical prophylaxis was the indication for 17.3% of used antimicrobials and exceeded one day in 60.7% of cases. Risk factors in the patient-based protocol were provided for 98% or more of the included patients and all were independently associated with both presence of HAI and receiving an antimicrobial agent. The patient-based protocol required more work than the unit-based protocol, but allowed collecting detailed data and analysis of risk factors for HAI and antimicrobial use.

  2. Naltrexone versus acamprosate in the treatment of alcohol dependence: A multi-centre, randomized, double-blind, placebo-controlled trial.

    Science.gov (United States)

    Morley, Kirsten C; Teesson, Maree; Reid, Sophie C; Sannibale, Claudia; Thomson, Clare; Phung, Nghi; Weltman, Martin; Bell, James R; Richardson, Kylie; Haber, Paul S

    2006-10-01

    To compare the efficacy of acamprosate and naltrexone in the treatment of alcohol dependence. A double-blind, placebo-controlled trial. Three treatment centres in Australia. A total of 169 alcohol dependent subjects were given naltrexone (50 mg/day), acamprosate (1998 mg/day) or placebo for 12 weeks. All subjects were offered manualized compliance therapy, a brief intervention that targets problems that may affect treatment compliance such as ambivalence and misperceptions about medication. Time to the first drink, time to first relapse, drinks per drinking day and cumulative abstinence. In intention-to-treat analyses, there were no differences between groups on outcome measures of drinking, craving or biochemical markers. Similarly, analyses of the 94 subjects that completed the study in full and demonstrated 80% compliance, revealed no significant treatment effects. Differential treatment effects were identified after stratification according to scores on the Alcohol Dependence Scale (ADS) and Depression Anxiety and Stress Scale (DASS). A significant beneficial treatment effect on time to first relapse was revealed for subjects with 'no depression' allocated to naltrexone (n = 56; P relapse prevention of alcoholism amongst those with low levels of clinical depression and alcohol dependence severity. No effect of acamprosate was found in our sample.

  3. Scientific Satellites

    Science.gov (United States)

    1967-01-01

    noise signal level exceeds 10 times the normal background. EXPERIMENTS FOR SATELLITE ASTRONOMY 615 ANTENNA MONOPOLE -., PREAMPLFE = BANDPASS-FILTER...OUTPUT TO AND DETECTOR TELEMETRYCHANNELS (18) CALIBRATION NOISE MATRIX CLOCK NOISE SOURCE ’ON’ SOURCE COMMAND F ROM PROGRAMERP ANTENNA MONOPOLE FIGURE 13...Animal Tempera- ture Sensing for Studying the Effect of Prolonged Orbital Flight on the Circadian Rhythms of Pocket Mice . Unmanned Spacecraft Meeting

  4. Solar satellites

    Energy Technology Data Exchange (ETDEWEB)

    Poher, C.

    1982-01-01

    A reference system design, projected costs, and the functional concepts of a satellite solar power system (SSPS) for converting sunlight falling on solar panels of a satellite in GEO to a multi-GW beam which could be received by a rectenna on earth are outlined. Electricity transmission by microwaves has been demonstrated, and a reference design system for supplying 5 GW dc to earth was devised. The system will use either monocrystalline Si or concentrator GaAs solar cells for energy collection in GEO. Development is still needed to improve the lifespan of the cells. Currently, the cell performance degrades 50 percent in efficiency after 7-8 yr in space. Each SSPS satellite would weigh either 34,000 tons (Si) or 51,000 tons (GaAs), thereby requiring the fabrication of a heavy lift launch vehicle or a single-stage-to-orbit transport in order to minimize launch costs. Costs for the solar panels have been estimated at $500/kW using the GaAs technology, with transport costs for materials to GEO being $40/kg.

  5. Solar satellites

    Science.gov (United States)

    Poher, C.

    A reference system design, projected costs, and the functional concepts of a satellite solar power system (SSPS) for converting sunlight falling on solar panels of a satellite in GEO to a multi-GW beam which could be received by a rectenna on earth are outlined. Electricity transmission by microwaves has been demonstrated, and a reference design system for supplying 5 GW dc to earth was devised. The system will use either monocrystalline Si or concentrator GaAs solar cells for energy collection in GEO. Development is still needed to improve the lifespan of the cells. Currently, the cell performance degrades 50 percent in efficiency after 7-8 yr in space. Each SSPS satellite would weigh either 34,000 tons (Si) or 51,000 tons (GaAs), thereby requiring the fabrication of a heavy lift launch vehicle or a single-stage-to-orbit transport in order to minimize launch costs. Costs for the solar panels have been estimated at $500/kW using the GaAs technology, with transport costs for materials to GEO being $40/kg.

  6. Associated factors and outcomes for OXA-232 Carbapenem-resistant Enterobacteriaceae infections in a tertiary care centre in Mexico City: A case-control-control study.

    Science.gov (United States)

    Torres-González, Pedro; Ortiz-Brizuela, Edgar; Cervera-Hernandez, Miguel Enrique; Bobadilla-Del Valle, Miriam; Martínez-Gamboa, Areli; Sifuentes-Osornio, José; Ponce-de-Leon, Alfredo

    2016-10-01

    We describe the outcomes and factors associated with OXA-232 producing carbapenem-resistant Enterobacteriaceae infections. A case-control-control study was performed; each case of infection by a carbapenem-resistant/OXA-232 (OXA-232-cases, n=27) was matched by isolation site, species, and date, with 2 cases of infection by carbapenem-susceptible/third-generation cephalosporin-susceptible (TGCS-controls, n=54) and 2 cases by carbapenem-susceptible/ESBL producing Enterobacteriaceae (ESBL-controls, n=54); 66% were urinary tract and 18.5% intra-abdominal infections. In the multivariable analysis with ESBL-controls, previous use β-lactam/β-lactamase antibiotics (OR 6.2; 95% CI 1.6-23.8) and, third-generation cephalosporins (OR 0.2; 95% CI 0.05-0.8) were associated with OXA-232 infection; with TGSC-controls previous use of β-lactam/β-lactamase antibiotics (OR 3.7; 95% 1.1-12.0) was associated. Among the OXA-232-cases, 29% received imipenem/cilastatin or meropenem, 11.1% ceftriaxone, 22.2% a carbapenem-based combination and 33.3% other antimicrobials as treatment. Previous β-lactam/β-lactamase antibiotics are associated with OXA-232 infections, and some may be treated with other active carbapenems or, in the absence of ESBL, third-generation cephalosporins. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. The Effect of Using Assessment Instruments on Substance-abuse Outpatients' Adherence to Treatment: a Multi-centre Randomised Controlled Trial

    Directory of Open Access Journals (Sweden)

    Broekaert Eric

    2011-05-01

    Full Text Available Abstract Background Drop-out is an important problem in the treatment of substance use disorder. The focus of this study was to investigate the effectiveness of within treatment assessment with feedback directly to patients with multiple substance use disorder on outpatient individual treatment adherence. Feedback consisted of personal resources' and readiness to change status and progress that facilitate or hinder change, thereby using graphical representation. Methods Informed consent was obtained from both the control and experimental groups to be involved in research and follow-up. Following Zelen's single consent design, baseline participants (n = 280 were randomised (sample-size-estimation: 80%power, p=.05, 2-sided and treatment consent was obtained from those allocated to the experiment (n = 142. In both groups, equal numbers of patients did not attend sessions after allocation. So, 227 persons were analyzed according to intention-to-treat analysis (ITT: experiment n = 116;control n = 111. Excluding refusals 211 participants remained for per-protocol analysis (PP: experiment n = 100; control n = 111, The study was conducted in five outpatient treatment-centres of a large network (De Sleutel in Belgium. Participants were people with multiple substance use disorder -abuse and dependence- who had asked for treatment and who had been advised to start individual treatment after a standardised admission assessment with the European Addiction Severity Index. The experimental condition consisted of informing the patient about the intervention and of subsequent assessments plus feedback following a protocol within the first seven sessions. Assessments were made with the Readiness to Change Questionnaire and the Personal Resources Diagnostic System. The control group received the usual treatment without within treatment assessment with feedback. The most important outcome measure in this analysis of the study was the level of adherence to treatment

  8. The effect of TCM acupuncture on hot flushes among menopausal women (ACUFLASH study: A study protocol of an ongoing multi-centre randomised controlled clinical trial

    Directory of Open Access Journals (Sweden)

    Borud Einar K

    2007-02-01

    Full Text Available Abstract Background After menopause, 10–20% of all women have nearly intolerable hot flushes. Long term use of hormone replacement therapy involves a health risk, and many women seek alternative strategies to relieve climacteric complaints. Acupuncture is one of the most frequently used complementary therapies in Norway. We designed a study to evaluate whether Traditional Chinese Medicine acupuncture-care together with self-care is more effective than self-care alone to relieve climacteric complaints. Methods/Design The study is a multi-centre pragmatic randomised controlled trial with two parallel arms. Participants are postmenopausal women who document ≥7 flushes/24 hours and who are not using hormone replacement therapy or other medication that may influence flushes. According to power calculations 200 women are needed to detect a 50% reduction in flushes, and altogether 286 women will be recruited to allow for a 30% dropout rate. The treatment group receives 10 sessions of Traditional Chinese Medicine acupuncture-care and self-care; the control group will engage in self-care only. A team of experienced Traditional Chinese Medicine acupuncturists give acupuncture treatments. Discussion The study tests acupuncture as a complete treatment package including the therapeutic relationship and expectation. The intervention period lasts for 12 weeks, with follow up at 6 and 12 months. Primary endpoint is change in daily hot flush frequency in the two groups from baseline to 12 weeks; secondary endpoint is health related quality of life, assessed by the Women's Health Questionnaire. We also collect data on Traditional Chinese Medicine diagnoses, and we examine treatment experiences using a qualitative approach. Finally we measure biological variables, to examine potential mechanisms for the effect of acupuncture. The study is funded by The Research Council of Norway.

  9. Advanced communications technology satellite high burst rate link evaluation terminal power control and rain fade software test plan, version 1.0

    Science.gov (United States)

    Reinhart, Richard C.

    1993-01-01

    The Power Control and Rain Fade Software was developed at the NASA Lewis Research Center to support the Advanced Communications Technology Satellite High Burst Rate Link Evaluation Terminal (ACTS HBR-LET). The HBR-LET is an experimenters terminal to communicate with the ACTS for various experiments by government, university, and industry agencies. The Power Control and Rain Fade Software is one segment of the Control and Performance Monitor (C&PM) Software system of the HBR-LET. The Power Control and Rain Fade Software automatically controls the LET uplink power to compensate for signal fades. Besides power augmentation, the C&PM Software system is also responsible for instrument control during HBR-LET experiments, control of the Intermediate Frequency Switch Matrix on board the ACTS to yield a desired path through the spacecraft payload, and data display. The Power Control and Rain Fade Software User's Guide, Version 1.0 outlines the commands and procedures to install and operate the Power Control and Rain Fade Software. The Power Control and Rain Fade Software Maintenance Manual, Version 1.0 is a programmer's guide to the Power Control and Rain Fade Software. This manual details the current implementation of the software from a technical perspective. Included is an overview of the Power Control and Rain Fade Software, computer algorithms, format representations, and computer hardware configuration. The Power Control and Rain Fade Test Plan provides a step-by-step procedure to verify the operation of the software using a predetermined signal fade event. The Test Plan also provides a means to demonstrate the capability of the software.

  10. Flight Dynamics Operations Management of the Large and Heterogeneous Eutelsat Fleet of Commercial Satellites

    Science.gov (United States)

    Bellido, E.

    The EUTELSAT FDU (Flight Dynamics Unit) manages the resources to perform the typical activities of the large satellite operators and faces the usual difficulties raising from a vast and heterogeneous fleet. At present 20 satellites from 9 different platforms/sub-platforms are controlled from our Satellite Control Centre. The FDU was created in 2002 with the aim to respond to the operational needs of a growing fleet in terms of number of satellites and activities. It is at present composed of 6 engineering staff with the objective to provide operations service covering the whole lifecycle of the satellites from the procurement phase till the decommissioning. The most demanding activity is the daily operations, which must ensure maximum safety and continuity of service with the highest efficiency. Solutions have been applied from different areas: management, structure, operations organisation, processes, facilities, quality standards, etc. In addition to this, EUTELSAT is a growing communications operator and the FDU needs to contribute to the global objectives of the company. This paper covers our approach.

  11. A pragmatic multi-centre randomised controlled trial of fluid loading in high-risk surgical patients undergoing major elective surgery--the FOCCUS study.

    Science.gov (United States)

    Cuthbertson, Brian H; Campbell, Marion K; Stott, Stephen A; Elders, Andrew; Hernández, Rodolfo; Boyers, Dwayne; Norrie, John; Kinsella, John; Brittenden, Julie; Cook, Jonathan; Rae, Daniela; Cotton, Seonaidh C; Alcorn, David; Addison, Jennifer; Grant, Adrian

    2011-01-01

    Fluid strategies may impact on patient outcomes in major elective surgery. We aimed to study the effectiveness and cost-effectiveness of pre-operative fluid loading in high-risk surgical patients undergoing major elective surgery. This was a pragmatic, non-blinded, multi-centre, randomised, controlled trial. We sought to recruit 128 consecutive high-risk surgical patients undergoing major abdominal surgery. The patients underwent pre-operative fluid loading with 25 ml/kg of Ringer's solution in the six hours before surgery. The control group had no pre-operative fluid loading. The primary outcome was the number of hospital days after surgery with cost-effectiveness as a secondary outcome. A total of 111 patients were recruited within the study time frame in agreement with the funder. The median pre-operative fluid loading volume was 1,875 ml (IQR 1,375 to 2,025) in the fluid group compared to 0 (IQR 0 to 0) in controls with days in hospital after surgery 12.2 (SD 11.5) days compared to 17.4 (SD 20.0) and an adjusted mean difference of 5.5 days (median 2.2 days; 95% CI -0.44 to 11.44; P = 0.07). There was a reduction in adverse events in the fluid intervention group (P = 0.048) and no increase in fluid based complications. The intervention was less costly and more effective (adjusted average cost saving: £2,047; adjusted average gain in benefit: 0.0431 quality adjusted life year (QALY)) and has a high probability of being cost-effective. Pre-operative intravenous fluid loading leads to a non-significant reduction in hospital length of stay after high-risk major surgery and is likely to be cost-effective. Confirmatory work is required to determine whether these effects are reproducible, and to confirm whether this simple intervention could allow more cost-effective delivery of care. Prospective Clinical Trials, ISRCTN32188676.

  12. I-MOVE multi-centre case control study 2010-11: overall and stratified estimates of influenza vaccine effectiveness in Europe.

    Directory of Open Access Journals (Sweden)

    Esther Kissling

    Full Text Available BACKGROUND: In the third season of I-MOVE (Influenza Monitoring Vaccine Effectiveness in Europe, we undertook a multicentre case-control study based on sentinel practitioner surveillance networks in eight European Union (EU member states to estimate 2010/11 influenza vaccine effectiveness (VE against medically-attended influenza-like illness (ILI laboratory-confirmed as influenza. METHODS: Using systematic sampling, practitioners swabbed ILI/ARI patients within seven days of symptom onset. We compared influenza-positive to influenza laboratory-negative patients among those meeting the EU ILI case definition. A valid vaccination corresponded to > 14 days between receiving a dose of vaccine and symptom onset. We used multiple imputation with chained equations to estimate missing values. Using logistic regression with study as fixed effect we calculated influenza VE adjusting for potential confounders. We estimated influenza VE overall, by influenza type, age group and among the target group for vaccination. RESULTS: We included 2019 cases and 2391 controls in the analysis. Adjusted VE was 52% (95% CI 30-67 overall (N = 4410, 55% (95% CI 29-72 against A(H1N1 and 50% (95% CI 14-71 against influenza B. Adjusted VE against all influenza subtypes was 66% (95% CI 15-86, 41% (95% CI -3-66 and 60% (95% CI 17-81 among those aged 0-14, 15-59 and ≥60 respectively. Among target groups for vaccination (N = 1004, VE was 56% (95% CI 34-71 overall, 59% (95% CI 32-75 against A(H1N1 and 63% (95% CI 31-81 against influenza B. CONCLUSIONS: Results suggest moderate protection from 2010-11 trivalent influenza vaccines against medically-attended ILI laboratory-confirmed as influenza across Europe. Adjusted and stratified influenza VE estimates are possible with the large sample size of this multi-centre case-control. I-MOVE shows how a network can provide precise summary VE measures across Europe.

  13. Effectiveness of a Hospital-Based Work Support Intervention for Female Cancer Patients – A Multi-Centre Randomised Controlled Trial

    Science.gov (United States)

    Tamminga, Sietske J.; Verbeek, Jos H. A. M.; Bos, Monique M. E. M.; Fons, Guus; Kitzen, Jos J. E. M.; Plaisier, Peter W.; Frings-Dresen, Monique H. W.; de Boer, Angela G. E. M.

    2013-01-01

    Objective One key aspect of cancer survivorship is return-to-work. Unfortunately, many cancer survivors face problems upon their return-to-work. For that reason, we developed a hospital-based work support intervention aimed at enhancing return-to-work. We studied effectiveness of the intervention compared to usual care for female cancer patients in a multi-centre randomised controlled trial. Methods Breast and gynaecological cancer patients who were treated with curative intent and had paid work were randomised to the intervention group (n = 65) or control group (n = 68). The intervention involved patient education and support at the hospital and improvement of communication between treating and occupational physicians. In addition, we asked patient's occupational physician to organise a meeting with the patient and the supervisor to make a concrete gradual return-to-work plan. Outcomes at 12 months of follow-up included rate and time until return-to-work (full or partial), quality of life, work ability, work functioning, and lost productivity costs. Time until return-to-work was analyzed with Kaplan-Meier survival analysis. Results Return-to-work rates were 86% and 83% (p = 0.6) for the intervention group and control group when excluding 8 patients who died or with a life expectancy of months at follow-up. Median time from initial sick leave to partial return-to-work was 194 days (range 14–435) versus 192 days (range 82–465) (p = 0.90) with a hazard ratio of 1.03 (95% CI 0.64–1.6). Quality of life and work ability improved statistically over time but did not differ statistically between groups. Work functioning and costs did not differ statistically between groups. Conclusion The intervention was easily implemented into usual psycho-oncological care and showed high return-to-work rates. We failed to show any differences between groups on return-to-work outcomes and quality of life scores. Further research is needed to study which aspects of

  14. Large multi-centre pilot randomized controlled trial testing a low-cost, tailored, self-help smoking cessation text message intervention for pregnant smokers (MiQuit).

    Science.gov (United States)

    Naughton, Felix; Cooper, Sue; Foster, Katharine; Emery, Joanne; Leonardi-Bee, Jo; Sutton, Stephen; Jones, Matthew; Ussher, Michael; Whitemore, Rachel; Leighton, Matthew; Montgomery, Alan; Parrott, Steve; Coleman, Tim

    2017-07-01

    To estimate the effectiveness of pregnancy smoking cessation support delivered by short message service (SMS) text message and key parameters needed to plan a definitive trial. Multi-centre, parallel-group, single-blinded, individual randomized controlled trial. Sixteen antenatal clinics in England. Four hundred and seven participants were randomized to the intervention (n = 203) or usual care (n = 204). Eligible women were 5 pre-pregnancy), were able to receive and understand English SMS texts and were not already using text-based cessation support. All participants received a smoking cessation leaflet; intervention participants also received a 12-week programme of individually tailored, automated, interactive, self-help smoking cessation text messages (MiQuit). Seven smoking outcomes, including validated continuous abstinence from 4 weeks post-randomization until 36 weeks gestation, design parameters for a future trial and cost-per-quitter. Using the validated, continuous abstinence outcome, 5.4% (11 of 203) of MiQuit participants were abstinent versus 2.0% (four of 204) of usual care participants [odds ratio (OR) = 2.7, 95% confidence interval (CI) = 0.93-9.35]. The Bayes factor for this outcome was 2.23. Completeness of follow-up at 36 weeks gestation was similar in both groups; provision of self-report smoking data was 64% (MiQuit) and 65% (usual care) and abstinence validation rates were 56% (MiQuit) and 61% (usual care). The incremental cost-per-quitter was £133.53 (95% CI = -£395.78 to 843.62). There was some evidence, although not conclusive, that a text-messaging programme may increase cessation rates in pregnant smokers when provided alongside routine NHS cessation care. © 2017 The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction.

  15. The IDvIP Trial: A two-centre randomised double-blind controlled trial comparing intramuscular diamorphine and intramuscular pethidine for labour analgesia

    Directory of Open Access Journals (Sweden)

    Thomas Peter

    2011-07-01

    Full Text Available Abstract Background Intramuscular pethidine is routinely used throughout the UK for labour analgesia. Studies have suggested that pethidine provides little pain relief in labour and has a number of side effects affecting mother and neonate. It can cause nausea, vomiting and dysphoria in mothers and can cause reduced fetal heart rate variability and accelerations. Neonatal effects include respiratory depression and impaired feeding. There are few large studies comparing the relative side effects and efficacy of different opioids in labour. A small trial comparing intramuscular pethidine with diamorphine, showed diamorphine to have some benefits over pethidine when used for labour analgesia but the study did not investigate the adverse effects of either opioid. Methods The Intramuscular Diamorphine versus Intramuscular Pethidine (IDvIP trial is a randomised double-blind two centre controlled trial comparing intramuscular diamorphine and pethidine regarding their analgesic efficacy in labour and their side effects in mother, fetus and neonate. Information about the trial will be provided to women in the antenatal period or in early labour. Consent and recruitment to the trial will be obtained when the mother requests opioid analgesia. The sample size requirement is 406 women with data on primary outcomes. The maternal primary outcomes are pain relief during the first 3 hours after trial analgesia and specifically pain relief after 60 minutes. The neonatal primary outcomes are need for resuscitation and Apgar Score Discussion If the trial demonstrates that diamorphine provides better analgesia with fewer side effects in mother and neonate this could lead to a change in national practice and result in diamorphine becoming the preferred intramuscular opioid for analgesia in labour. Trial Registration ISRCTN14898678 Eudra No: 2006-003250-18, REC Reference No: 06/Q1702/95, MHRA Authorisation No: 1443/0001/001-0001, NIHR UKCRN reference 6895, RfPB grant

  16. Radiological and pathological findings of interval cancers in a multi-centre, randomized, controlled trial of mammographic screening in women from age 40-41 years

    International Nuclear Information System (INIS)

    Evans, A.J.; Kutt, E.; Record, C.; Waller, M.; Bobrow, L.; Moss, S.

    2007-01-01

    Aim: The aim of this study was to analyse the radiographic findings of the screening mammograms of women with interval cancer who participated in a multi-centre, randomized, controlled trial of mammographic screening in women from age 40-48 years. Materials and methods: The screening and diagnostic mammograms of 208 women with interval cancers were reviewed. Abnormalities were classified as malignant, subtle and non-specific. Results: Eighty-seven (42%) of women had true, 66 (32%) occult and 55 (26%) false-negative interval cancers. The features most frequently missed or misinterpreted were granular microcalcification (38%), asymmetric density (27%) and distortion (22%). Thirty-seven percent of abnormal previous screens were classified as malignant, 39% subtle change and 21% as non-specific. Granular calcifications were significantly more common on the diagnostic mammograms of false-negative interval cancers than those of true interval cancers (28 versus 14%, p = 0.04). Occult interval cancers were more likely to be <10 mm and <15 mm in invasive pathological size than other interval cancers (p = 0.03 and 0.005, respectively). True interval cancers were more likely to be histologically grade 3 than other interval cancers (p = 0.04). Women who developed true and false-negative interval cancers had similar background patterns, but women with occult cancers had a higher proportion of dense patterns (p < 0.05). Conclusion: Interval cancers in a young screening population have a high proportion of occult lesions that are small and occur in dense background patterns. The proportion of interval cancers that are false negative is similar that seen in older populations and granular microcalcification is the commonest missed mammographic feature

  17. The geo-spatial information infrastructure at the Centre for Control and Prevention of Zoonoses, University of Ibadan, Nigeria: an emerging sustainable One-Health pavilion.

    Science.gov (United States)

    Olugasa, B O

    2014-12-01

    The World-Wide-Web as a contemporary means of information sharing offers a platform for geo-spatial information dissemination to improve education about spatio-temporal patterns of disease spread at the human-animal-environment interface in developing countries of West Africa. In assessing the quality of exposure to geospatial information applications among students in five purposively selected institutions in West Africa, this study reviewed course contents and postgraduate programmes in zoonoses surveillance. Geospatial information content and associated practical exercises in zoonoses surveillance were scored.. Seven criteria were used to categorize and score capability, namely, spatial data capture; thematic map design and interpretation; spatio-temporal analysis; remote sensing of data; statistical modelling; the management of spatial data-profile; and web-based map sharing operation within an organization. These criteria were used to compute weighted exposure during training at the institutions. A categorical description of institution with highest-scoring of computed Cumulative Exposure Point Average (CEPA) was based on an illustration with retrospective records of rabies cases, using data from humans, animals and the environment, that were sourced from Grand Bassa County, Liberia to create and share maps and information with faculty, staff, students and the neighbourhood about animal bite injury surveillance and spatial distribution of rabies-like illness. Uniformly low CEPA values (0-1.3) were observed across academic departments. The highest (3.8) was observed at the Centre for Control and Prevention of Zoonoses (CCPZ), University of Ibadan, Nigeria, where geospatial techniques were systematically taught, and thematic and predictive maps were produced and shared online with other institutions in West Africa. In addition, a short course in zoonosis surveillance, which offers inclusive learning in geospatial applications, is taught at CCPZ. The paper

  18. Protocol for a single-centre, randomised controlled study of a preoperative rehabilitation bundle in the frail and elderly undergoing abdominal surgery.

    Science.gov (United States)

    Abdullah, Hairil Rizal; Lien, Victoria Peixin; Ong, Hwee Kuan; Er, Pei Ling; Hao, Ying; Khan, Shariq Ali; Liu, Christopher Weiyang

    2017-08-04

    Frail patients have decreased physiological reserves and consequently, they are unable to recover as quickly from surgery. Frailty, as an entity, is a risk factor of increased morbidity and mortality. It is also associated with a longer time to discharge. This trial is undertaken to determine if a novel prehabilitation protocol (10-day bundle of interventions-physiotherapy, nutritional supplementation and cognitive training) can reduce the postoperative length of stay of frail patients who are undergoing elective abdominal surgery, compared with standard care. This is a prospective, single-centre, randomised controlled trial with two parallel arms. 62 patients who are frail and undergoing elective abdominal surgery will be recruited and randomised to receive either a novel prehabilitation protocol or standard care. Participants will receive telephone reminders preoperatively to encourage protocol compliance. Data will be collected for up to 30 days postoperatively. The primary outcome of the trial will be the postoperative length of stay and the secondary outcomes are the postoperative complications and functional recovery during the hospital admission. This study has been approved by the Singapore General Hospital Institutional Review Board (CIRB Ref: 2016/2584). The study is also listed on ClinicalTrials.gov (Trial number: NCT02921932). All participants will sign an informed consent form before randomisation and translators will be made available to non-English speaking patients. The results of this study will be published in peer-reviewed journals as well as national and international conferences. The data collected will also be made available in a public data repository. NCT02921932 (ClinicalTrials.gov). © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  19. SAP Nuclear Competence Centre

    International Nuclear Information System (INIS)

    Andrlova, Z.

    2009-01-01

    In this issue we continue and introduce the SAP Nuclear Competence Centre and its head Mr. Igor Dzama. SAP Nuclear Competence Centrum is one of the fi rst competence centres outside ENEL headquarters. It should operate in Slovakia and should have competencies within the whole Enel group. We are currently dealing with the issues of organisation and funding. We are trying to balance the accountability to the NPP directors and to the management of the competence centres at Enel headquarters; we are looking at the relations between the competence centres within the group and defining the services that we will provide for the NPPs. author)

  20. Canadian Irradiation Centre

    International Nuclear Information System (INIS)

    1987-05-01

    The Canadian Irradiation Centre is a non-profit cooperative project between Atomic Energy of Canada Limited, Radiochemical Company and Universite du Quebec, Institut Armand-Frappier, Centre for Applied Research in Food Science. The Centre's objectives are to develop, demonstrate and promote Canada's radiation processing technology and its applications by conducting applied research; training technical, professional and scientific personnel; educating industry and government; demonstrating operational and scientific procedures; developing processing procedures and standards, and performing product and market acceptance trials. This pamphlet outlines the history of radoation technology and the services offered by the Canadian Irradiation Centre

  1. Protocol for a multi-centre randomised controlled trial comparing arthroscopic hip surgery to physiotherapy-led care for femoroacetabular impingement (FAI): the Australian FASHIoN trial.

    Science.gov (United States)

    Murphy, Nicholas J; Eyles, Jillian; Bennell, Kim L; Bohensky, Megan; Burns, Alexander; Callaghan, Fraser M; Dickenson, Edward; Fary, Camdon; Grieve, Stuart M; Griffin, Damian R; Hall, Michelle; Hobson, Rachel; Kim, Young Jo; Linklater, James M; Lloyd, David G; Molnar, Robert; O'Connell, Rachel L; O'Donnell, John; O'Sullivan, Michael; Randhawa, Sunny; Reichenbach, Stephan; Saxby, David J; Singh, Parminder; Spiers, Libby; Tran, Phong; Wrigley, Tim V; Hunter, David J

    2017-09-26

    Femoroacetabular impingement syndrome (FAI), a hip disorder affecting active young adults, is believed to be a leading cause of hip osteoarthritis (OA). Current management approaches for FAI include arthroscopic hip surgery and physiotherapy-led non-surgical care; however, there is a paucity of clinical trial evidence comparing these approaches. In particular, it is unknown whether these management approaches modify the future risk of developing hip OA. The primary objective of this randomised controlled trial is to determine if participants with FAI who undergo hip arthroscopy have greater improvements in hip cartilage health, as demonstrated by changes in delayed gadolinium-enhanced magnetic resonance imaging (MRI) of cartilage (dGEMRIC) index between baseline and 12 months, compared to those who undergo physiotherapy-led non-surgical management. This is a pragmatic, multi-centre, two-arm superiority randomised controlled trial comparing hip arthroscopy to physiotherapy-led management for FAI. A total of 140 participants with FAI will be recruited from the clinics of participating orthopaedic surgeons, and randomly allocated to receive either surgery or physiotherapy-led non-surgical care. The surgical intervention involves arthroscopic FAI surgery from one of eight orthopaedic surgeons specialising in this field, located in three different Australian cities. The physiotherapy-led non-surgical management is an individualised physiotherapy program, named Personalised Hip Therapy (PHT), developed by a panel to represent the best non-operative care for FAI. It entails at least six individual physiotherapy sessions over 12 weeks, and up to ten sessions over six months, provided by experienced musculoskeletal physiotherapists trained to deliver the PHT program. The primary outcome measure is the change in dGEMRIC score of a ROI containing both acetabular and femoral head cartilages at the chondrolabral transitional zone of the mid-sagittal plane between baseline and

  2. Health-care-associated infections in neonates, children, and adolescents: an analysis of paediatric data from the European Centre for Disease Prevention and Control point-prevalence survey.

    Science.gov (United States)

    Zingg, Walter; Hopkins, Susan; Gayet-Ageron, Angèle; Holmes, Alison; Sharland, Mike; Suetens, Carl

    2017-04-01

    In 2011-12, the European Centre for Disease Prevention and Control (ECDC) held the first Europe-wide point-prevalence survey of health-care-associated infections in acute care hospitals. We analysed paediatric data from this survey, aiming to calculate the prevalence and type of health-care-associated infections in children and adolescents in Europe and to determine risk factors for infection in this population. Point-prevalence surveys took place from May, 2011, to November, 2012, in 1149 hospitals in EU Member States, Iceland, Norway, and Croatia. Patients present on the ward at 0800 h on the day of the survey and who were not discharged at the time of the survey were included. Data were collected by locally trained health-care workers according to patient-based or unit-based protocols. We extracted data from the ECDC database for all paediatric patients (age 0-18 years). We report adjusted prevalence for health-care-associated infections by clustering at the hospital and country level. We also calculated risk factors for development of health-care-associated infections with use of a generalised linear mixed-effects model. We analysed data for 17 273 children and adolescents from 29 countries. 770 health-care-associated infections were reported in 726 children and adolescents, corresponding to a prevalence of 4·2% (95% CI 3·7-4·8). Bloodstream infections were the most common type of infection (343 [45%] infections), followed by lower respiratory tract infections (171 [22%]), gastrointestinal infections (64 [8%]), eye, ear, nose, and throat infections (55 [7%]), urinary tract infections (37 [5%]), and surgical-site infections (34 [4%]). The prevalence of infections was highest in paediatric intensive care units (15·5%, 95% CI 11·6-20·3) and neonatal intensive care units (10·7%, 9·0-12·7). Independent risk factors for infection were age younger than 12 months, fatal disease (via ultimately and rapidly fatal McCabe scores), prolonged length of stay, and

  3. The effect of perhexiline on myocardial protection during coronary artery surgery: a two-centre, randomized, double-blind, placebo-controlled trial.

    Science.gov (United States)

    Drury, Nigel E; Howell, Neil J; Calvert, Melanie J; Weber, Ralf J M; Senanayake, Eshan L; Lewis, Michael E; Hyde, Jonathan A J; Green, David H; Mascaro, Jorge G; Wilson, Ian C; Graham, Timothy R; Rooney, Stephen J; Viant, Mark R; Freemantle, Nick; Frenneaux, Michael P; Pagano, Domenico

    2015-03-01

    Perhexiline is thought to modulate metabolism by inhibiting mitochondrial carnitine palmitoyltransferase-1, reducing fatty acid uptake and increasing carbohydrate utilization. This study assessed whether preoperative perhexiline improves markers of myocardial protection in patients undergoing coronary artery bypass graft surgery and analysed its effect on the myocardial metabolome. In a prospective, randomized, double-blind, placebo-controlled trial, patients at two centres were randomized to receive either oral perhexiline or placebo for at least 5 days prior to surgery. The primary outcome was a low cardiac output episode in the first 6 h. All pre-specified analyses were conducted according to the intention-to-treat principle with a statistical power of 90% to detect a relative risk of 0.5 and a conventional one-sided α-value of 0.025. A subset of pre-ischaemic left ventricular biopsies was analysed using mass spectrometry-based metabolomics. Over a 3-year period, 286 patients were randomized, received the intervention and were included in the analysis. The incidence rate of a low cardiac output episode in the perhexiline arm was 36.7% (51/139) vs 34.7% (51/147) in the control arm [odds ratio (OR) 0.92, 95% confidence interval (CI) 0.56-1.50, P = 0.74]. Perhexiline was associated with a reduction in the cardiac index at 6 h [difference in means 0.19, 95% CI 0.07-0.31, P = 0.001] and an increase in inotropic support in the first 12 h (OR 0.55, 95% CI 0.34-0.89, P = 0.015). There were no significant differences in myocardial injury with troponin-T or electrocardiogram, reoperation, renal dysfunction or length of stay. No difference in the preischaemic left ventricular metabolism was identified between groups on metabolomics analysis. Preoperative perhexiline does not improve myocardial protection in patients undergoing coronary surgery and in fact reduced perioperative cardiac output, increasing the need for inotropic support. Perhexiline has no significant effect

  4. Contributions of the CEA-Valduc Centre control to the understanding of the transfers of atmospheric tritiated water into the different parts of the environment

    International Nuclear Information System (INIS)

    Guetat, P.; Vichot, L.; Tognelli, A.

    2009-01-01

    After a description of the geological environment of the Valduc Centre dedicated to tritium purification and tritiated waste processing and storage, this document presents the assessment of quantities of tritiated water released by the Valduc Centre and of their evolution in the hydro-geological environment. It provides in situ macroscopically observed data on the transfer mechanisms of water into the different parts of the environment and into the food chain by means. This is made possible by the exceptional traceability of tritiated water. Finally, a comparison between computational models and experimental measurements is given

  5. Effects of the daily consumption of protein enriched bread and protein enriched drinking yoghurt on the total protein intake in older adults in a rehabilitation centre: a single blind randomised controlled trial.

    Science.gov (United States)

    van Til, A J; Naumann, E; Cox-Claessens, I J H M; Kremer, S; Boelsma, E; de van der Schueren, M A E

    2015-05-01

    To investigate the effects of protein enriched bread and drinking yoghurt, substituting regular products, on the total protein intake and the distribution of protein intake over the day in older adults. A single blind randomised controlled trial. Rehabilitation centre. Older adults (≥ 55 years) admitted to a rehabilitation centre after hospital discharge (n=34). Participants received a high protein diet (protein enriched bread and protein enriched drinking yoghurt; n=17) or a regular diet (regular bread and regular drinking yoghurt; n=17) for three consecutive weeks. Total protein intake and protein intake per meal, measured twice weekly over a three weeks period (six measurements per participant). Compared with controls, patients who received the protein enriched products had a significantly higher protein intake (115.3 g/d vs 72.5 g/d, Pconsumption of protein enriched products improves protein distribution over the day.

  6. Design and implementation of a radiation hardened silicon on sapphire (SOS) embedded signal conditioning unit controller (SCUC) for the RAPID instrument on the Cluster satellites

    International Nuclear Information System (INIS)

    Ersland, L.

    1992-07-01

    The Cluster mission consistens of four spacecrafts equipped with instruments capable of making comprehensive measurements of plasma particles and electromagnetic fields. The RAPID (Research with Adaptive Particle Imaging Detectors) spectrometer is one of many instruments on board the Cluster satellites. It is designed for fast analysis of energetic electrons and ions with a complete coverage of the unit sphere in phase space. This thesis describes the development and testing of an embedded controller for the Spectroscopic Camera for Electrons, Neutral and Ion Compositions (SCENIC), which is a part of the RAPID instrument. The design is implemented in two different CMOS circuit technologies, namely Actel's Field Programmable Gate Arrays and GEC Plessey's CMOS Silicon On Sapphire (SOS) gate array. The prototypes of the SOS gate array have been verified and characterized. This includes measurements of DC and AC parameters under different conditions, including total dose of gamma irradiation. 42 refs., 92 figs., 44 tabs

  7. Security Concepts for Satellite Links

    Science.gov (United States)

    Tobehn, C.; Penné, B.; Rathje, R.; Weigl, A.; Gorecki, Ch.; Michalik, H.

    2008-08-01

    The high costs to develop, launch and maintain a satellite network makes protecting the assets imperative. Attacks may be passive such as eavesdropping on the payload data. More serious threat are active attacks that try to gain control of the satellite, which may lead to the total lost of the satellite asset. To counter these threats, new satellite and ground systems are using cryptographic technologies to provide a range of services: confidentiality, entity & message authentication, and data integrity. Additionally, key management cryptographic services are required to support these services. This paper describes the key points of current satellite control and operations, that are authentication of the access to the satellite TMTC link and encryption of security relevant TM/TC data. For payload data management the key points are multi-user ground station access and high data rates both requiring frequent updates and uploads of keys with the corresponding key management methods. For secure satellite management authentication & key negotiation algorithms as HMAC-RIPEMD160, EC- DSA and EC-DH are used. Encryption of data uses algorithms as IDEA, AES, Triple-DES, or other. A channel coding and encryption unit for payload data provides download data rates up to Nx250 Mbps. The presented concepts are based on our experience and heritage of the security systems for all German MOD satellite projects (SATCOMBw2, SAR-Lupe multi- satellite system and German-French SAR-Lupe-Helios- II systems inter-operability) as well as for further international (KOMPSAT-II Payload data link system) and ESA activities (TMTC security and GMES).

  8. Client Centred Desing

    DEFF Research Database (Denmark)

    Ørngreen, Rikke; Nielsen, Janni; Levinsen, Karin

    2008-01-01

    In this paper we argue for the use of Client Centred preparation phases when designing complex systems. Through Client Centred Design human computer interaction can extend the focus on end-users to alse encompass the client's needs, context and resources....

  9. EFSA (European Food Safety Authority) and ECDC (European Centre for Disease Prevention and Control), 2015. The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2014

    DEFF Research Database (Denmark)

    Helwigh, Birgitte; Porsbo, Lone Jannok; Boysen, Louise

    This report of the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of the zoonoses monitoring activities carried out in 2014 in 32 European countries (28 Member States (MS) and four non-MS). Campylobacteriosis was the most commonly re......, molluscs and products thereof’. The report further summarises trends and sources along the food chain of tuberculosis due to Mycobacterium bovis, Brucella, Trichinella, Echinococcus, Toxoplasma, rabies, Coxiella burnetii (Q fever), West Nile virus and tularaemia....

  10. EFSA and ECDC (European Food Safety Authority and European Centre for Disease Prevention and Control), 2015. The European Union Summary Report on Trends and Sources of Zoonoses, Zoonotic Agents and Food-borne Outbreaks in 2013

    DEFF Research Database (Denmark)

    Helwigh, Birgitte

    This report of the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of the zoonoses monitoring activities carried out in 2013 in 32 European countries (28 Member States and four non-Member States). Campylobacter iosis was the most comm...... chain of tuberculosis due to Mycobacterium bovis, Brucella, Trichinella, Echinococcus, Toxoplasma , rabies, Coxiella burnetii (Q fever), West Nile Virus and tularaemia....

  11. EFSA and ECDC (European Food Safety Authority and European Centre for Disease Prevention and Control), 2015. The European Union Summary Report on Trends and Sources of Zoonoses, Zoonotic Agents and Food-borne Outbreaks in 2013

    OpenAIRE

    Helwigh, Birgitte

    2015-01-01

    This report of the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of the zoonoses monitoring activities carried out in 2013 in 32 European countries (28 Member States and four non-Member States). Campylobacter iosis was the most commonly reported zoonosis. After several years of an increasing European Union (EU) trend, the human Campylobacter iosis notification rate has stabilised. In food and animals no EU trends were observed a...

  12. EFSA (European Food Safety Authority) and ECDC (European Centre for Disease Prevention and Control), 2015. The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2014

    OpenAIRE

    Helwigh, Birgitte; Porsbo, Lone Jannok; Boysen, Louise; Bager, Flemming

    2015-01-01

    This report of the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of the zoonoses monitoring activities carried out in 2014 in 32 European countries (28 Member States (MS) and four non-MS). Campylobacteriosis was the most commonly reported zoonosis with an increase in confirmed human cases in the European Union (EU) since 2008. In food the occurrence of Campylobacter remained high in broiler meat. The decreasing EU trend for conf...

  13. Analysis of Satellite and Airborne Imagery for Detection of Water Hyacinth and Other Invasive Floating Macrophytes and Tracking of Aquatic Weed Control Efficacy

    Science.gov (United States)

    Potter, Christopher

    2016-01-01

    Waterways of the Sacramento San Joaquin Delta have recently become infested with invasive aquatic weeds such as floating water hyacinth (Eichhoria crassipes) and water primrose (Ludwigia peploides). These invasive plants cause many negative impacts, including, but not limited to: the blocking of waterways for commercial shipping and boating; clogging of irrigation screens, pumps and canals; and degradation of biological habitat through shading. Zhang et al. (1997, Ecological Applications, 7(3), 1039-1053) used NASA Landsat satellite imagery together with field calibration measurements to map physical and biological processes within marshlands of the San Francisco Bay. Live green biomass (LGB) and related variables were correlated with a simple vegetation index ratio of red and near infra-red bands from Landsat images. More recently, the percent (water area) cover of water hyacinth plotted against estimated LGB of emergent aquatic vegetation in the Delta from September 2014 Landsat imagery showed an 80 percent overall accuracy. For the past two years, we have partnered with the U. S. Department of Agriculture (USDA) and the Department of Plant Sciences, University of California at Davis to conduct new validation surveys of water hyacinth and water primrose coverage and LGB in Delta waterways. A plan is underway to transfer decision support tools developed at NASA's Ames Research Center based on Landsat satellite images to improve Delta-wide integrated management of floating aquatic weeds, while reducing chemical control costs. The main end-user for this application project will be the Division of Boating and Waterways (DBW) of the California Department of Parks and Recreation, who has the responsibility for chemical control of water hyacinth in the Delta.

  14. Satellite recovery - Attitude dynamics of the targets

    Science.gov (United States)

    Cochran, J. E., Jr.; Lahr, B. S.

    1986-01-01

    The problems of categorizing and modeling the attitude dynamics of uncontrolled artificial earth satellites which may be targets in recovery attempts are addressed. Methods of classification presented are based on satellite rotational kinetic energy, rotational angular momentum and orbit and on the type of control present prior to the benign failure of the control system. The use of approximate analytical solutions and 'exact' numerical solutions to the equations governing satellite attitude motions to predict uncontrolled attitude motion is considered. Analytical and numerical results are presented for the evolution of satellite attitude motions after active control termination.

  15. Regional Centres for Space Science and Technology Education Affiliated to the United Nations

    Science.gov (United States)

    Aquino, A. J. A.; Haubold, H. J.

    2010-05-01

    Based on resolutions of the United Nations General Assembly, Regional Centres for space science and technology education were established in India, Morocco, Nigeria, Brazil and Mexico. Simultaneously, education curricula were developed for the core disciplines of remote sensing, satellite communications, satellite meteorology, and space and atmospheric science. This paper provides a brief report on the status of the operation of the Regional Centres and draws attention to their educational activities.

  16. A Randomised Controlled Trial of Two Early Intervention Programs for Young Children with Autism: Centre-Based with Parent Program and Home-Based

    Science.gov (United States)

    Roberts, Jacqueline; Williams, Katrina; Carter, Mark; Evans, David; Parmenter, Trevor; Silove, Natalie; Clark, Trevor; Warren, Anthony

    2011-01-01

    This study compares outcomes of early intervention programs for young children with autism; an individualised home-based program (HB), a small group centre-based program for children combined with a parent training and support group (CB) and a non-treatment comparison group (WL). Outcome measures of interest include social and communication skill…

  17. Improving person-centred care in nursing homes through dementia-care mapping: design of a cluster-randomised controlled trial.

    NARCIS (Netherlands)

    Ven, G. van de; Draskovic, I.; Adang, E.M.M.; Donders, R.; Post, A.; Zuidema, S.U.; Koopmans, R.T.C.M.; Vernooij-Dassen, M.J.F.J.

    2012-01-01

    BACKGROUND: The effectiveness and efficiency of nursing-home dementia care are suboptimal: there are high rates of neuropsychiatric symptoms among the residents and work-related stress among the staff. Dementia-care mapping is a person-centred care method that may alleviate both the resident and the

  18. Geostationary Satellite (GOES) Images

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Visible and Infrared satellite imagery taken from radiometer instruments on SMS (ATS) and GOES satellites in geostationary orbit. These satellites produced...

  19. Evaluating the PRASE patient safety intervention - a multi-centre, cluster trial with a qualitative process evaluation: study protocol for a randomised controlled trial.

    Science.gov (United States)

    Sheard, Laura; O'Hara, Jane; Armitage, Gerry; Wright, John; Cocks, Kim; McEachan, Rosemary; Watt, Ian; Lawton, Rebecca

    2014-10-29

    Estimates show that as many as one in 10 patients are harmed while receiving hospital care. Previous strategies to improve safety have focused on developing incident reporting systems and changing systems of care and professional behaviour, with little involvement of patients. The need to engage with patients about the quality and safety of their care has never been more evident with recent high profile reviews of poor hospital care all emphasising the need to develop and support better systems for capturing and responding to the patient perspective on their care. Over the past 3 years, our research team have developed, tested and refined the PRASE (Patient Reporting and Action for a Safe Environment) intervention, which gains patient feedback about quality and safety on hospital wards. A multi-centre, cluster, wait list design, randomised controlled trial with an embedded qualitative process evaluation. The aim is to assess the efficacy of the PRASE intervention, in achieving patient safety improvements over a 12-month period.The trial will take place across 32 hospital wards in three NHS Hospital Trusts in the North of England. The PRASE intervention comprises two tools: (1) a 44-item questionnaire which asks patients about safety concerns and issues; and (2) a proforma for patients to report (a) any specific patient safety incidents they have been involved in or witnessed and (b) any positive experiences. These two tools then provide data which are fed back to wards in a structured feedback report. Using this report, ward staff are asked to hold action planning meetings (APMs) in order to action plan, then implement their plans in line with the issues raised by patients in order to improve patient safety and the patient experience.The trial will be subjected to a rigorous qualitative process evaluation which will enable interpretation of the trial results. fieldworker diaries, ethnographic observation of APMs, structured interviews with APM lead and collection

  20. The IDvIP trial: a two-centre randomised double-blind controlled trial comparing intramuscular diamorphine and intramuscular pethidine for labour analgesia.

    Science.gov (United States)

    Wee, Michael Y K; Tuckey, Jenny P; Thomas, Peter; Burnard, Sara

    2011-07-08

    Intramuscular pethidine is routinely used throughout the UK for labour analgesia. Studies have suggested that pethidine provides little pain relief in labour and has a number of side effects affecting mother and neonate. It can cause nausea, vomiting and dysphoria in mothers and can cause reduced fetal heart rate variability and accelerations. Neonatal effects include respiratory depression and impaired feeding. There are few large studies comparing the relative side effects and efficacy of different opioids in labour. A small trial comparing intramuscular pethidine with diamorphine, showed diamorphine to have some benefits over pethidine when used for labour analgesia but the study did not investigate the adverse effects of either opioid. The Intramuscular Diamorphine versus Intramuscular Pethidine (IDvIP) trial is a randomised double-blind two centre controlled trial comparing intramuscular diamorphine and pethidine regarding their analgesic efficacy in labour and their side effects in mother, fetus and neonate. Information about the trial will be provided to women in the antenatal period or in early labour. Consent and recruitment to the trial will be obtained when the mother requests opioid analgesia. The sample size requirement is 406 women with data on primary outcomes. The maternal primary outcomes are pain relief during the first 3 hours after trial analgesia and specifically pain relief after 60 minutes. The neonatal primary outcomes are need for resuscitation and Apgar Score analgesia, whether method of analgesia would be used again, use of Entonox, umbilical arterial and venous pH, fetal heart rate, meconium staining, time from delivery to first breath, Apgar scores at 5 mins, naloxone requirement, transfer to neonatal intensive care unit, neonatal haemoglobin oxygen saturation at 30, 60, 90, and 120 mins after delivery, and neonatal sedation and feeding behaviour during first 2 hours. If the trial demonstrates that diamorphine provides better analgesia

  1. Large-scale fuel cycle centres

    International Nuclear Information System (INIS)

    Smiley, S.H.; Black, K.M.

    1977-01-01

    The US Nuclear Regulatory Commission (NRC) has considered the nuclear energy centre concept for fuel cycle plants in the Nuclear Energy Centre Site Survey 1975 (NECSS-75) Rep. No. NUREG-0001, an important study mandated by the US Congress in the Energy Reorganization Act of 1974 which created the NRC. For this study, the NRC defined fuel cycle centres as consisting of fuel reprocessing and mixed-oxide fuel fabrication plants, and optional high-level waste and transuranic waste management facilities. A range of fuel cycle centre sizes corresponded to the fuel throughput of power plants with a total capacity of 50,000-300,000MW(e). The types of fuel cycle facilities located at the fuel cycle centre permit the assessment of the role of fuel cycle centres in enhancing the safeguard of strategic special nuclear materials - plutonium and mixed oxides. Siting fuel cycle centres presents a smaller problem than siting reactors. A single reprocessing plant of the scale projected for use in the USA (1500-2000t/a) can reprocess fuel from reactors producing 50,000-65,000MW(e). Only two or three fuel cycle centres of the upper limit size considered in the NECSS-75 would be required in the USA by the year 2000. The NECSS-75 fuel cycle centre evaluation showed that large-scale fuel cycle centres present no real technical siting difficulties from a radiological effluent and safety standpoint. Some construction economies may be achievable with fuel cycle centres, which offer opportunities to improve waste-management systems. Combined centres consisting of reactors and fuel reprocessing and mixed-oxide fuel fabrication plants were also studied in the NECSS. Such centres can eliminate shipment not only of Pu but also mixed-oxide fuel. Increased fuel cycle costs result from implementation of combined centres unless the fuel reprocessing plants are commercial-sized. Development of Pu-burning reactors could reduce any economic penalties of combined centres. The need for effective fissile

  2. 21 June 2010 - TUBITAK Vice President A. Adli signing the guest book with CERN Director-General R. Heuer, visiting the ATLAS control room at Point 1 with Former Collaboration Spokesperson P. Jenni and CMS Control Centre, building 354, with Collaboration Spokesperson G. Tonelli. Throughout accompanied by Adviser J. Ellis.

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    21 June 2010 - TUBITAK Vice President A. Adli signing the guest book with CERN Director-General R. Heuer, visiting the ATLAS control room at Point 1 with Former Collaboration Spokesperson P. Jenni and CMS Control Centre, building 354, with Collaboration Spokesperson G. Tonelli. Throughout accompanied by Adviser J. Ellis.

  3. WHEDA study: Effectiveness of occupational therapy at home for older people with dementia and their caregivers - the design of a pragmatic randomised controlled trial evaluating a Dutch programme in seven German centres

    Directory of Open Access Journals (Sweden)

    Vernooij-Dassen Myrra

    2009-10-01

    Full Text Available Abstract Background A recent Dutch mono-centre randomised controlled trial has shown that occupational therapy improves daily functioning in dementia. The aim of this present study is to compare the effects of the Dutch community occupational therapy programme with a community occupational therapy consultation on daily functioning in older people with mild or moderate dementia and their primary caregivers in a German multi-centre context. Methods/Design A multi-centre single blind randomised controlled trial design is being used in seven health care centres (neurological, psychiatric and for older people in urban regions. Patients are 1:1 randomised to treatment or control group. Assessors are blind to group assignment and perform measurements on both groups at baseline, directly after intervention at 6 weeks and at 16, 26 and 52 weeks follow-up. A sample of 140 community dwelling older people (aged >65 years with mild or moderate dementia and their primary caregivers is planned. The experimental intervention consists of an evidence-based community occupational therapy programme including 10 sessions occupational therapy at home. The control intervention consists of one community occupational therapy consultation based on information material of the Alzheimer Society. Providers of both interventions are occupational therapists experienced in treatment of cognitively impaired older people and trained in both programmes. 'Community' indicates that occupational therapy intervention occurs in the person's own home. The primary outcome is patients' daily functioning assessed with the performance scale of the Interview for Deterioration in Daily Living Activities in Dementia and video tapes of daily activities rated by external raters blind to group assignment using the Perceive, Recall, Plan and Perform System of Task Analysis. Secondary outcomes are patients' and caregivers' quality of life, mood and satisfaction with treatment; the caregiver

  4. Un nouveau centre de recherche soutient les efforts d'adaptation ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    9 juil. 2014 ... Image satellite du delta du Nil. José Alberto Gonçalves Pereira. Entretien avec. Mohamed Abdrabo est le directeur général de l'Alexandria Research Centre for Adaptation to Climate Change (ARCA), un nouveau centre de recherche qui soutient les politiques d'adaptation adoptées par le gouvernement ...

  5. Interim Service ISDN Satellite (ISIS) simulator development for advanced satellite designs and experiments

    Science.gov (United States)

    Pepin, Gerard R.

    1992-01-01

    The simulation development associated with the network models of both the Interim Service Integrated Services Digital Network (ISDN) Satellite (ISIS) and the Full Service ISDN Satellite (FSIS) architectures is documented. The ISIS Network Model design represents satellite systems like the Advanced Communications Technology Satellite (ACTS) orbiting switch. The FSIS architecture, the ultimate aim of this element of the Satellite Communications Applications Research (SCAR) Program, moves all control and switching functions on-board the next generation ISDN communications satellite. The technical and operational parameters for the advanced ISDN communications satellite design will be obtained from the simulation of ISIS and FSIS engineering software models for their major subsystems. Discrete event simulation experiments will be performed with these models using various traffic scenarios, design parameters, and operational procedures. The data from these simulations will be used to determine the engineering parameters for the advanced ISDN communications satellite.

  6. The impact of a disease management program (COACH on the attainment of better cardiovascular risk control in dyslipidaemic patients at primary care centres (The DISSEMINATE Study: a randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Selvaraj Francis Jude

    2012-10-01

    Full Text Available Abstract Background To evaluate the efficacy of Counselling and Advisory Care for Health (COACH programme in managing dyslipidaemia among primary care practices in Malaysia. This open-label, parallel, randomised controlled trial compared the COACH programme delivered by primary care physicians alone (PCP arm and primary care physicians assisted by nurse educators (PCP-NE arm. Methods This was a multi-centre, open label, randomised trial of a disease management programme (COACH among dyslipidaemic patients in 21 Malaysia primary care practices. The participating centres enrolled 297 treatment naïve subjects who had the primary diagnosis of dyslipidaemia; 149 were randomised to the COACH programme delivered by primary care physicians assisted by nurse educators (PCP-NE and 148 to care provided by primary care physicians (PCP alone. The primary efficacy endpoint was the mean percentage change from baseline LDL-C at week 24 between the 2 study arms. Secondary endpoints included mean percentage change from baseline of lipid profile (TC, LDL-C, HDL-C, TG, TC: HDL ratio, Framingham Cardiovascular Health Risk Score and absolute risk change from baseline in blood pressure parameters at week 24. The study also assessed the sustainability of programme efficacy at week 36. Results Both study arms demonstrated improvement in LDL-C from baseline. The least squares (LS mean change from baseline LDL-C were −30.09% and −27.54% for PCP-NE and PCP respectively. The difference in mean change between groups was 2.55% (p=0.288, with a greater change seen in the PCP-NE arm. Similar observations were made between the study groups in relation to total cholesterol change at week 24. Significant difference in percentage change from baseline of HDL-C were observed between the PCP-NE and PCP groups, 3.01%, 95% CI 0.12-5.90, p=0.041, at week 24. There was no significant difference in lipid outcomes between 2 study groups at week 36 (12 weeks after the programme had

  7. The impact of a disease management program (COACH) on the attainment of better cardiovascular risk control in dyslipidaemic patients at primary care centres (The DISSEMINATE Study): a randomised controlled trial.

    Science.gov (United States)

    Selvaraj, Francis Jude; Mohamed, Mafauzy; Omar, Khairani; Nanthan, Sudha; Kusiar, Zainab; Subramaniam, Selvaraj Y; Ali, Norsiah; Karanakaran, Kamalakaran; Ahmad, Fauziah; Low, Wilson H H

    2012-10-10

    To evaluate the efficacy of Counselling and Advisory Care for Health (COACH) programme in managing dyslipidaemia among primary care practices in Malaysia. This open-label, parallel, randomised controlled trial compared the COACH programme delivered by primary care physicians alone (PCP arm) and primary care physicians assisted by nurse educators (PCP-NE arm). This was a multi-centre, open label, randomised trial of a disease management programme (COACH) among dyslipidaemic patients in 21 Malaysia primary care practices. The participating centres enrolled 297 treatment naïve subjects who had the primary diagnosis of dyslipidaemia; 149 were randomised to the COACH programme delivered by primary care physicians assisted by nurse educators (PCP-NE) and 148 to care provided by primary care physicians (PCP) alone. The primary efficacy endpoint was the mean percentage change from baseline LDL-C at week 24 between the 2 study arms. Secondary endpoints included mean percentage change from baseline of lipid profile (TC, LDL-C, HDL-C, TG, TC: HDL ratio), Framingham Cardiovascular Health Risk Score and absolute risk change from baseline in blood pressure parameters at week 24. The study also assessed the sustainability of programme efficacy at week 36. Both study arms demonstrated improvement in LDL-C from baseline. The least squares (LS) mean change from baseline LDL-C were -30.09% and -27.54% for PCP-NE and PCP respectively. The difference in mean change between groups was 2.55% (p=0.288), with a greater change seen in the PCP-NE arm. Similar observations were made between the study groups in relation to total cholesterol change at week 24. Significant difference in percentage change from baseline of HDL-C were observed between the PCP-NE and PCP groups, 3.01%, 95% CI 0.12-5.90, p=0.041, at week 24. There was no significant difference in lipid outcomes between 2 study groups at week 36 (12 weeks after the programme had ended). Patients who received coaching and advice from

  8. Potential of Natural Ventilation in Shopping Centres

    DEFF Research Database (Denmark)

    Diederichsen, Alice; Friis, Kristina; Brohus, Henrik

    2008-01-01

    The indoor environmental quality (IEQ) is a fundamental requirement for a well performing shopping centre. This paper contains a pilot study of the potential of using hybrid ventilation (a combination of automatically controlled natural and mechanical ventilation - respectively NV and MV) in shop......The indoor environmental quality (IEQ) is a fundamental requirement for a well performing shopping centre. This paper contains a pilot study of the potential of using hybrid ventilation (a combination of automatically controlled natural and mechanical ventilation - respectively NV and MV......) in shopping centres with focus on both the achieved IEQ and energy consumptions for air movement. By thermal building simulations it is found that there exists an interesting potential for hybrid ventilation of shopping centres, which can lead to great savings in the electrical energy consumptions...

  9. The Bruce Energy Centre

    International Nuclear Information System (INIS)

    Jones, R.I.

    1982-06-01

    The Bruce Energy Centre Development Corporation is a joint venture of the Ontario Energy Corporation and 6 private companies formed to market surplus steam from the Bruce Nuclear Power Development. The corporation will also sell or lease land near Bruce NPD. The Bruce Energy Centre has an energy output of 900 BTU per day per dollar invested. Potential customers include greenhouse operators, aquaculturalists, food and beverage manufacturers, and traditional manufacturers

  10. CENTRE FOR GEOMETRICAL METROLOGY

    DEFF Research Database (Denmark)

    De Chiffre, Leonardo

    The objective of this Annual Report is to give a general introduction to CGM as well as to give an account of the tasks carried out using the facilities of CGM's Instrument Centre during 1998 and 1999.......The objective of this Annual Report is to give a general introduction to CGM as well as to give an account of the tasks carried out using the facilities of CGM's Instrument Centre during 1998 and 1999....

  11. Kagawa Satellite “STARS” in Shikoku

    Science.gov (United States)

    Nohmi, Masahiro; Yamamoto, Takeshi; Andatsu, Akira; Takagi, Yohei; Nishikawa, Yusuke; Kaneko, Takashi; Kunitom, Daisuke

    The Space Tethered Autonomous Robotic Satellite (STARS) is being developed in Kagawa University, and it will be launched by the H-IIA rocket by Japan Aerospace Exploration Agency (JAXA) in summer 2008. STARS is the first satellite developed in Shikoku, and its specific characteristics are: (i) mother and daughter satellites, which have basic satellite system respectively, and those are launched at the same time; (ii) large space system more than 5m by extending tether; (iii) robotic system, the daughter satellite controls its arm link and the mother satellite controls tether extension. Development of STARS in Kagawa University demonstrates space technology in local community, which has been considered to be a national project. Also, it promotes popularization, enlightenment, and understanding of space technology in local area of the Kagawa prefecture and around it.

  12. The CSN's Information Centre: a necessary venture

    International Nuclear Information System (INIS)

    Calvo, A.

    1999-01-01

    Every year, around 10,000 pupils will visit the CSN's Information Centre, an exposition area which was created with the intention of explaining simply but strictly, what radiations are, for what they are used, what risks they hold and how they are controlled. Opened in October, 1998, encouraged by Parliamentary urging, the Centre is a path to CSN Information for citizens to use. (Author)

  13. Automatic centring and bonding of lenses

    Science.gov (United States)

    Krey, Stefan; Heinisch, J.; Dumitrescu, E.

    2007-05-01

    We present an automatic bonding station which is able to center and bond individual lenses or doublets to a barrel with sub micron centring accuracy. The complete manufacturing cycle includes the glue dispensing and UV curing. During the process the state of centring is continuously controlled by the vision software, and the final result is recorded to a file for process statistics. Simple pass or fail results are displayed to the operator at the end of the process.

  14. Predictive fault-tolerant control of an all-thruster satellite in 6-DOF motion via neural network model updating

    Science.gov (United States)

    Tavakoli, M. M.; Assadian, N.

    2018-03-01

    The problem of controlling an all-thruster spacecraft in the coupled translational-rotational motion in presence of actuators fault and/or failure is investigated in this paper. The nonlinear model predictive control approach is used because of its ability to predict the future behavior of the system. The fault/failure of the thrusters changes the mapping between the commanded forces to the thrusters and actual force/torque generated by the thruster system. Thus, the basic six degree-of-freedom kinetic equations are separated from this mapping and a set of neural networks are trained off-line to learn the kinetic equations. Then, two neural networks are attached to these trained networks in order to learn the thruster commands to force/torque mappings on-line. Different off-nominal conditions are modeled so that neural networks can detect any failure and fault, including scale factor and misalignment of thrusters. A simple model of the spacecraft relative motion is used in MPC to decrease the computational burden. However, a precise model by the means of orbit propagation including different types of perturbation is utilized to evaluate the usefulness of the proposed approach in actual conditions. The numerical simulation shows that this method can successfully control the all-thruster spacecraft with ON-OFF thrusters in different combinations of thruster fault and/or failure.

  15. The use of modern dressings in managing split-thickness skin graft donor sites: a single-centre randomised controlled trial.

    Science.gov (United States)

    Kazanavičius, M; Cepas, A; Kolaityte, V; Simoliuniene, R; Rimdeika, R

    2017-06-02

    To identify the most appropriate, most suitable and most efficient dressing for split-thickness skin graft (STSG) donor sites. Comparing the wound healing rate, pain severity and duration, as well as the dressing change frequency in four randomised patient groups. A single-centre non-blinded randomised controlled trial was carried out during 2010-2014. All patients treated for skin defects/lesions (due to burns, trauma or ulcers) using STSG were included in the study. All patients were randomly allocated in four different donor site treatment groups; polyurethane (PU group, Mepilex); polyurethane with silicone membrane (PUSM group; Mepilex border,); transparent, breathable film (TBF group; Mepitel film) and cotton gauze dressings (CG group) using Excel 2007. We evaluated: wound healing time, pain severity and duration, the frequency of dressing change, donor site re-epithelialisation, donor site complications (signs of inflammation or infection). Patients were assessed on postoperative days: 1, 3, 6, 9, 12, 15, 18 and 21. After random allocation of study participants the number of patients in each group were: PU group n=25; PUSM group n=24; TBF group n=24; CG group n=25. The groups were homogenous according to gender, age, main pathology, donor site area and wound size. The STSG donor site healing time varied from 9 to 21 days. The mean healing time in the CG group was 14.76 days, whereas in the PU, PUSM, and TBF group it was significantly shorter; 12.25 days, 11.63 days and 10 days, respectively. Patients in the TBF group demonstrated the most rapid healing time with 66.7% of STSG donor sites healed by postoperative day 9. The pain duration interval in modern dressing groups (PU, PUSM and TBF groups) was 0-9 days, whereas it was 6-18 day in the CS group. Pain intensity mean on postoperative day 1 was 2.21 in the PU group; 1.67 in the PUSM group; 1.46 in the TBF group and 3.04 in the CG group. The average pain duration in Group PU, PUSM, and TBF was 4.08 days; 2

  16. China: Possible Missile Technology Transfers from U.S. Satellite Export Policy - Actions and Chronology

    National Research Council Canada - National Science Library

    Kan, Shirley A

    2001-01-01

    .... Some critics opposed satellite exports to China, while others were concerned that the Clinton Administration relaxed export controls and monitoring of commercial satellites in moving the licensing...

  17. Asteroid Satellites

    Science.gov (United States)

    Merline, W. J.

    2001-11-01

    Discovery and study of small satellites of asteroids or double asteroids can yield valuable information about the intrinsic properties of asteroids themselves and about their history and evolution. Determination of the orbits of these moons can provide precise masses of the primaries, and hence reliable estimates of the fundamental property of bulk density. This reveals much about the composition and structure of the primary and will allow us to make comparisons between, for example, asteroid taxonomic type and our inventory of meteorites. The nature and prevalence of these systems will also give clues as to the collisional environment in which they formed, and have further implications for the role of collisions in shaping our solar system. A decade ago, binary asteroids were more of a theoretical curiosity. In 1993, the Galileo spacecraft allowed the first undeniable detection of an asteroid moon, with the discovery of Dactyl, a small moon of Ida. Since that time, and particularly in the last year, the number of known binaries has risen dramatically. Previously odd-shaped and lobate near-Earth asteroids, observed by radar, have given way to signatures indicating, almost certainly, that at least four NEAs are binary systems. The tell-tale lightcurves of several other NEAs reveal a high likelihood of being double. Indications are that among the NEAs, there may be a binary frequency of several tens of percent. Among the main-belt asteroids, we now know of 6 confirmed binary systems, although their overall frequency is likely to be low, perhaps a few percent. The detections have largely come about because of significant advances in adaptive optics systems on large telescopes, which can now reduce the blurring of the Earth's atmosphere to compete with the spatial resolution of space-based imaging (which itself, via HST, is now contributing valuable observations). Most of these binary systems have similarities, but there are important exceptions. Searches among other

  18. The group-based social skills training SOSTA-FRA in children and adolescents with high functioning autism spectrum disorder--study protocol of the randomised, multi-centre controlled SOSTA--net trial.

    Science.gov (United States)

    Freitag, Christine M; Cholemkery, Hannah; Elsuni, Leyla; Kroeger, Anne K; Bender, Stephan; Kunz, Cornelia Ursula; Kieser, Meinhard

    2013-01-07

    Group-based social skills training (SST) has repeatedly been recommended as treatment of choice in high-functioning autism spectrum disorder (HFASD). To date, no sufficiently powered randomised controlled trial has been performed to establish efficacy and safety of SST in children and adolescents with HFASD. In this randomised, multi-centre, controlled trial with 220 children and adolescents with HFASD it is hypothesized, that add-on group-based SST using the 12 weeks manualised SOSTA-FRA program will result in improved social responsiveness (measured by the parent rated social responsiveness scale, SRS) compared to treatment as usual (TAU). It is further expected, that parent and self reported anxiety and depressive symptoms will decline and pro-social behaviour will increase in the treatment group. A neurophysiological study in the Frankfurt HFASD subgroup will be performed pre- and post treatment to assess changes in neural function induced by SST versus TAU. The SOSTA - net trial is designed as a prospective, randomised, multi-centre, controlled trial with two parallel groups. The primary outcome is change in SRS score directly after the intervention and at 3 months follow-up. Several secondary outcome measures are also obtained. The target sample consists of 220 individuals with ASD, included at the six study centres. This study is currently one of the largest trials on SST in children and adolescents with HFASD worldwide. Compared to recent randomised controlled studies, our study shows several advantages with regard to in- and exclusion criteria, study methods, and the therapeutic approach chosen, which can be easily implemented in non-university-based clinical settings. ISRCTN94863788--SOSTA--net: Group-based social skills training in children and adolescents with high functioning autism spectrum disorder.

  19. The group-based social skills training SOSTA-FRA in children and adolescents with high functioning autism spectrum disorder - study protocol of the randomised, multi-centre controlled SOSTA - net trial

    Directory of Open Access Journals (Sweden)

    Freitag Christine M

    2013-01-01

    Full Text Available Abstract Background Group-based social skills training (SST has repeatedly been recommended as treatment of choice in high-functioning autism spectrum disorder (HFASD. To date, no sufficiently powered randomised controlled trial has been performed to establish efficacy and safety of SST in children and adolescents with HFASD. In this randomised, multi-centre, controlled trial with 220 children and adolescents with HFASD it is hypothesized, that add-on group-based SST using the 12 weeks manualised SOSTA–FRA program will result in improved social responsiveness (measured by the parent rated social responsiveness scale, SRS compared to treatment as usual (TAU. It is further expected, that parent and self reported anxiety and depressive symptoms will decline and pro-social behaviour will increase in the treatment group. A neurophysiological study in the Frankfurt HFASD subgroup will be performed pre- and post treatment to assess changes in neural function induced by SST versus TAU. Methods/design The SOSTA – net trial is designed as a prospective, randomised, multi-centre, controlled trial with two parallel groups. The primary outcome is change in SRS score directly after the intervention and at 3 months follow-up. Several secondary outcome measures are also obtained. The target sample consists of 220 individuals with ASD, included at the six study centres. Discussion This study is currently one of the largest trials on SST in children and adolescents with HFASD worldwide. Compared to recent randomised controlled studies, our study shows several advantages with regard to in- and exclusion criteria, study methods, and the therapeutic approach chosen, which can be easily implemented in non-university-based clinical settings. Trial registration ISRCTN94863788 – SOSTA – net: Group-based social skills training in children and adolescents with high functioning autism spectrum disorder.

  20. Trends in communications satellites

    CERN Document Server

    Curtin, Denis J

    1979-01-01

    Trends in Communications Satellites offers a comprehensive look at trends and advances in satellite communications, including experimental ones such as NASA satellites and those jointly developed by France and Germany. The economic aspects of communications satellites are also examined. This book consists of 16 chapters and begins with a discussion on the fundamentals of electrical communications and their application to space communications, including spacecraft, earth stations, and orbit and wavelength utilization. The next section demonstrates how successful commercial satellite communicati

  1. A Challenging Trio in Space 'Routine' Operations of the Swarm Satellite Constellation

    Science.gov (United States)

    Diekmann, Frank-Jurgen; Clerigo, Ignacio; Albini, Giuseppe; Maleville, Laurent; Neto, Alessandro; Patterson, David; Nino, Ana Piris; Sieg, Detlef

    2016-08-01

    Swarm is the first ESA Earth Observation Mission with three satellites flying in a semi-controlled constellation. The trio is operated from ESA's satellite control centre ESOC in Darmstadt, Germany. The Swarm Flight Operations Segment consists of the typical elements of a satellite control system at ESOC, but had to be carefully tailored for this innovative mission. The main challenge was the multi-satellite system of Swarm, which necessitated the development of a Mission Control System with a multi-domain functionality, both in hardware and software and covering real-time and backup domains. This was driven by the need for extreme flexibility for constellation operations and parallel activities.The three months of commissioning in 2014 were characterized by a very tight and dynamically changing schedule of activities. All operational issues could be solved during that time, including the challenging orbit acquisition phase to achieve the final constellation.Although the formal spacecraft commissioning phase was concluded in spring 2014, the investigations for some payload instruments continue even today. The Electrical Field Instruments are for instance still being tested in order to characterize and improve science data quality. Various test phases also became necessary for the Accelerometers on the Swarm satellites. In order to improve the performance of the GPS Receivers for better scientific exploitation and to minimize the failures due to loss of synchronization, a number of parameter changes were commanded via on-board patches.Finally, to minimize the impact on operations, a new strategy had to be implemented to handle single/multi bit errors in the on-board mass Memories, defining when to ignore and when to restore the memory via a re-initialisation.The poster presentation summarizes the Swarm specific ground segment elements of the FOS and explains some of the extended payload commissioning operations, turning Swarm into a most demanding and challenging

  2. 'Away Days' in multi-centre randomised controlled trials: a questionnaire survey of their use and a case study on the effect of one Away Day on patient recruitment.

    Science.gov (United States)

    Jefferson, Laura; Cook, Liz; Keding, Ada; Brealey, Stephen; Handoll, Helen; Rangan, Amar

    2015-11-06

    'Away Days' (trial promotion and training events for trial site personnel) are a well-established method used by trialists to encourage engagement of research sites in the recruitment of patients to multi-centre randomised controlled trials (RCTs). We explored the use of Away Days in multi-centre RCTs and analysed the effect on patient recruitment in a case study. Members of the United Kingdom Trial Managers' Network were surveyed in June 2013 to investigate their experiences in the design and conduct of Away Days in RCTs. We used data from a multi-centre pragmatic surgical trial to explore the effects of an Away Day on the screening and recruitment of patients. A total of 94 people responded to the survey. The majority (78%), who confirmed had organised an Away Day previously, found them to be useful. This is despite their costs.. There was no evidence, however, from the analysis of data from a surgical trial that attendance at an Away Day increased the number of patients screened or recruited at participating sites. Although those responsible for managing RCTs in the UK tend to believe that trial Away Days are beneficial, evidence from a multi-centre surgical trial shows no improvement on a key indicator of trial success. This points to the need to carefully consider the aims, design and conduct of Away Days. Further more rigorous research nested within RCTs would be valuable to evaluate the design and conduct of Away Days. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  3. Resistance patterns and outcomes in intensive care unit (ICU)-acquired pneumonia. Validation of European Centre for Disease Prevention and Control (ECDC) and the Centers for Disease Control and Prevention (CDC) classification of multidrug resistant organisms.

    Science.gov (United States)

    Martin-Loeches, Ignacio; Torres, Antonio; Rinaudo, Mariano; Terraneo, Silvia; de Rosa, Francesca; Ramirez, Paula; Diaz, Emili; Fernández-Barat, Laia; Li Bassi, Gian Luigi; Ferrer, Miquel

    2015-03-01

    Bacterial resistance has become a major public health problem. To validate the definition of multidrug-resistant organisms (MDRO) based on the European Centre for Disease Prevention and Control (ECDC) and the Centers for Disease Control and Prevention (CDC) classification. Prospective, observational study in six medical and surgical Intensive-Care-Units (ICU) of a University hospital. Three-hundred-and-forty-three patients with ICU-acquired pneumonia (ICUAP) were prospectively enrolled, 140 patients had no microbiological confirmation (41%), 82 patients (24%) developed ICUAP for non-MDRO, whereas 121 (35%) were MDROs. Non-MDRO, MDRO and no microbiological confirmation patients did not present either a significant different previous antibiotic use (p 0.18) or previous hospital admission (p 0.17). Appropriate antibiotic therapy was associated with better ICU survival (105 [92.9%] vs. 74 [82.2%]; p = 0.03). An adjusted multivariate regression logistic analysis identified that only MDRO had a higher ICU-mortality than non-MDRO and no microbiological confirmation patients (OR 2.89; p < 0.05; 95% CI for Exp [β]. 1.02-8.21); Patients with MDRO ICUAP remained in ICU for a longer period than MDRO and no microbiological confirmation respectively (p < 0.01) however no microbiological confirmation patients had more often antibiotic consumption than culture positive ones. Patients who developed ICUAP due to MDRO showed a higher ICU-mortality than non-MDRO ones and use of ICU resources. No microbiological confirmation patients had more often antibiotic consumption than culture positive patients. Risk factors for MDRO may be important for the selection of initial antimicrobial therapy, in addition to local epidemiology. Copyright © 2014 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

  4. Energy centre microgrid model

    Energy Technology Data Exchange (ETDEWEB)

    Pasonen, R.

    2011-09-15

    A simulation model of Energy centre microgrid made with PSCAD simulation software version 4.2.1 has been built in SGEM Smart Grids and Energy Markets (SGEM) work package 6.6. Microgrid is an autonomous electric power system which can operate separate from common distribution system. The idea of energy centre microgrid concept was considered in Master of Science thesis 'Community Microgrid - A Building block of Finnish Smart Grid'. The name of energy centre microgrid comes from a fact that production and storage units are concentrated into a single location, an energy centre. This centre feeds the loads which can be households or industrial loads. Power direction flow on the demand side remains same compared to the current distribution system and allows to the use of standard fuse protection in the system. The model consists of photovoltaic solar array, battery unit, variable frequency boost converter, inverter, isolation transformer and demand side (load) model. The model is capable to automatically switch to islanded mode when there is a fault in outside grid and back to parallel operation mode when fault is removed. The modelled system responses well to load changes and total harmonic distortion related to 50Hz base frequency is kept under 1.5% while operating and feeding passive load. (orig.)

  5. Advanced satellite servicing facility studies

    Science.gov (United States)

    Qualls, Garry D.; Ferebee, Melvin J., Jr.

    1988-01-01

    A NASA-sponsored systems analysis designed to identify and recommend advanced subsystems and technologies specifically for a manned Sun-synchronous platform for satellite management is discussed. An overview of system design, manned and unmanned servicing facilities, and representative mission scenarios are given. Mission areas discussed include facility based satellite assembly, checkout, deployment, refueling, repair, and systems upgrade. The ferrying of materials and consumables to and from manufacturing platforms, deorbit, removal, repositioning, or salvage of satellites and debris, and crew rescue of any other manned vehicles are also examined. Impacted subsytems discussed include guidance navigation and control, propulsion, data management, power, thermal control, structures, life support, and radiation management. In addition, technology issues which would have significant impacts on the system design are discussed.

  6. The nuclear research centre at Bariloche, Argentina

    International Nuclear Information System (INIS)

    Abriata, J.P.

    2001-01-01

    The nuclear research centre at Bariloche (CAB) is one of the four centres under the Atomic Energy Commission of Argentina (CNEA). The research programme of CAB addresses various issues like nuclear reactor development, nuclear fuel and fuel cycle, applications of radioisotopes and radiation, and waste management. There is also a basic nuclear science component. The human resource development in the areas of physics and nuclear engineering is done in an associated Balseiro Institute which has undergraduate and graduate programmes as well as doctoral and postdoctoral research. The Centre interacts well with the society and provides services in the nuclear area. It has a close interaction with the nuclear sector of Argentina as also with many international organisations. Regulatory control over the Centre is carried out by the Nuclear Regulatory Authority of Argentina. (author)

  7. Study protocol, rationale and recruitment in a European multi-centre randomized controlled trial to determine the efficacy and safety of azithromycin maintenance therapy for 6 months in primary ciliary dyskinesia

    DEFF Research Database (Denmark)

    Kobbernagel, Helene Elgaard; Buchvald, Frederik F; Haarman, Eric G

    2016-01-01

    maintenance therapy in PCD. METHODS: The BESTCILIA trial is a European multi-centre, double-blind, randomized, placebo-controlled, parallel group study. The intervention is tablets of azithromycin 250/500 mg according to body weight or placebo administered three times a week for 6 months. Subjects...... prescribed in other chronic respiratory disorders. Furthermore, the trial will utilize the Lung clearance index and new, PCD-specific quality of life instruments as outcome measures for PCD. Recruitment is hampered by frequent occurrence of Pseudomonas aeruginosa infection, exacerbations at enrolment...

  8. Infection prevention and control measures and tools for the prevention of entry of carbapenem-resistant Enterobacteriaceae into healthcare settings: guidance from the European Centre for Disease Prevention and Control

    Directory of Open Access Journals (Sweden)

    A. P. Magiorakos

    2017-11-01

    Full Text Available Abstract Background Infections with carbapenem-resistant Enterobacteriaceae (CRE are increasingly being reported from patients in healthcare settings. They are associated with high patient morbidity, attributable mortality and hospital costs. Patients who are “at-risk” may be carriers of these multidrug-resistant Enterobacteriaceae (MDR-E. The purpose of this guidance is to raise awareness and identify the “at-risk” patient when admitted to a healthcare setting and to outline effective infection prevention and control measures to halt the entry and spread of CRE. Methods The guidance was created by a group of experts who were functioning independently of their organisations, during two meetings hosted by the European Centre for Disease Prevention and Control. A list of epidemiological risk factors placing patients “at-risk” for carriage with CRE was created by the experts. The conclusions of a systematic review on the prevention of spread of CRE, with the addition of expert opinion, were used to construct lists of core and supplemental infection prevention and control measures to be implemented for “at-risk” patients upon admission to healthcare settings. Results Individuals with the following profile are “at-risk” for carriage of CRE: a a history of an overnight stay in a healthcare setting in the last 12 months, b dialysis-dependent or cancer chemotherapy in the last 12 months, c known previous carriage of CRE in the last 12 months and d epidemiological linkage to a known carrier of a CRE. Core infection prevention and control measures that should be considered for all patients in healthcare settings were compiled. Preliminary supplemental measures to be implemented for “at-risk” patients on admission are: pre-emptive isolation, active screening for CRE, and contact precautions. Patients who are confirmed positive for CRE will need additional supplemental measures. Conclusions Strengthening the microbiological

  9. The ideal Atomic Centre

    International Nuclear Information System (INIS)

    Mas, R.

    1965-01-01

    The author presents considerations which should prove to be of interest to all those who have to design, to construct and to operate a nuclear research centre. A large number of the ideas presented can also be applied to non-nuclear scientific research centres. In his report the author reviews: various problems with which the constructor is faced: ground-plan, infrastructure, buildings and the large units of scientific equipment in the centre, and those problems facing the director: maintenance, production, supplies, security. The author stresses the relationship which ought to exist between the research workers and the management. With this aim in view he proposes the creation of National School for Administration in Research which would train administrative executives for public or private organisations; they would be specialised in the fields of fundamental or applied research. (author) [fr

  10. Results of the Ongoing Monitoring of the Position of a Geostationary Telecommunication Satellite by the Method of Spatially Separated Basis Receiving of Digital Satellite Television Signals

    Directory of Open Access Journals (Sweden)

    Bushuev F.

    2016-10-01

    Full Text Available The results of the ongoing monitoring of the position of geostationary telecommunication satellite Eutelsat-13B (13° East are presented in the article. The results were obtained using a radio engineering complex (RC of four stations receiving digital satellite television and a data processing centre. The stations are located in Kyiv, Mukachevo, Kharkiv and Mykolaiv.

  11. Netherlands Reactor Centre

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    Briefly reviews the last year's work of the twenty year old Netherlands Reactor Centre (RCN) in the fields of reactor safety, fissile material, nuclear fission, non-nuclear energy systems and overseas co-operation. The annual report thus summarised is the last one to appear under the name of RCN. The terms of reference of the organisation having been broadened to include research into energy supply in general, it is to be known in future as the Netherlands Energy Research Centre (ECN). (D.J.B.)

  12. The Structural Integrity Centre

    International Nuclear Information System (INIS)

    Tomkins, B.

    1987-01-01

    The paper concerns the development and work of the Structural Integrity Centre (SIC) at Risley Nuclear Laboratories, United Kingdom. The centre was set up to provide authoritative advice to plant designers and operators on the integrity and life assessment of structures and components across the reactor projects in the United Kingdom. A description is given of the structure and role of the SIC, as well as the Structural Integrity Assessment work. The assessment methods are described for thermally loaded structures and welded structures. Finally, defect significance assessment and environmental effects are outlined. (U.K.)

  13. Handbook of satellite applications

    CERN Document Server

    Madry, Scott; Camacho-Lara, Sergio

    2017-01-01

    The first edition of this ground breaking reference work was the most comprehensive reference source available about the key aspects of the satellite applications field. This updated second edition covers the technology, the markets, applications and regulations related to satellite telecommunications, broadcasting and networking—including civilian and military systems; precise satellite navigation and timing networks (i.e. GPS and others); remote sensing and meteorological satellite systems. Created under the auspices of the International Space University based in France, this brand new edition is now expanded to cover new innovative small satellite constellations, new commercial launching systems, innovation in military application satellites and their acquisition, updated appendices, a useful glossary and more.

  14. International research centre launched

    International Nuclear Information System (INIS)

    1965-01-01

    Full text: The first scientific research and educational institution to be set up on a completely international basis was officially inaugurated in Trieste on 5 October 1964 by the Director General of IAEA, Dr. Sigvard Eklund, when he opened the first seminar of the International Centre for Theoretical Physics. As evidence of the international nature of the institution he noted that the scientists who would work and teach there during the first year represented sixteen different countries. By the end of 1964, the Centre building was nearing completion and three of the five floors were occupied. A successful symposium had been held on the subject of plasma physics, and a score of professors and fellows were at work, from Bulgaria, Czechoslovakia, Greece, India, Japan, Jordan, the Netherlands, Norway, Pakistan, Poland, the United Kingdom, and the United States. A dozen scientific papers had been issued as preprints. The main purpose of the Centre is to foster the advancement of theoretical physics through training and research; at first the chief subject will be high-energy and elementary particle physics. Plasma physics, low energy physics and solid-state physics will also be dealt with. Special attention is paid to the needs of the developing countries. Of the 25 fellows selected for the academic year 1964-65, more than half are from South America, Africa and Asia. In conjunction with the Research Centre, there is an Advanced School for theoretical Physics to provide graduate training for fellows who need such preparation before they embark upon research. The Centre works under the guidance of a Scientific Council comprising the president, Prof. M. Sandoval-Vallarta (Nuclear Energy Commission of Mexico); Prof. A. Abragam (Saclay, France); Prof. R. Oppenheimer (Institute for Advanced Study, Princeton, USA); Dr. V. Soloviev (Dubna, USSR); Prof V.F. Weiskopf (Director General, CERN) ; Prof Abdus Salam (Imperial College, London) ; Prof. P. Budini (University of Trieste

  15. Study protocol: The development of a pilot study employing a randomised controlled design to investigate the feasibility and effects of a peer support program following discharge from a specialist first-episode psychosis treatment centre

    Directory of Open Access Journals (Sweden)

    Francey Shona

    2010-05-01

    Full Text Available Abstract Background Young people with first-episode psychosis (FEP are at risk of a range of negative outcomes. Specialist FEP services have been developed to provide comprehensive, multi-disciplinary treatment. However, these services are often available for a restricted period and the services that young people may be transferred to are less comprehensive. This represents a risk of drop out from treatment services in a group already considered to be at risk of disengagement. Peer support groups have been shown to improve social relationships among people with psychosis however individual peer support programs have not been tested on young people with first-episode psychosis; nor have they been tested at the point of discharge from services. Methods/design The study is an 18-month randomised controlled trial being conducted at Orygen Youth Health Research Centre in Melbourne, Australia. The aim of the study is to test the feasibility and effects of a 6-month peer support intervention delivered to young people with FEP over the period of discharge. Participants are young people aged 15-24 who are being discharged from a specialist first-episode psychosis treatment centre. There is a 6-month recruitment period. The intervention comprises two hours of contact per fortnight during which peer support workers can assist participants to engage with their new services, or other social and community activities. Participants will be assessed at baseline and post intervention (6 months. Discussion This paper describes the development of a randomised-controlled trial which aims to pilot a peer support program among young people who are being discharged from a specialist FEP treatment centre. If effective, the intervention could lead to benefits not only for participants over the discharge period, but for peer support workers as well. Trial registration The study was registered with the Australian New Zealand Clinical Trials Registry; number: ACTRN

  16. Electrophotometric observations of artificial satellites

    International Nuclear Information System (INIS)

    Vovchyk, Yeva; Blagodyr, Yaroslav; Kraynyuk, Gennadiy; Bilinsky, Andriy; Lohvynenko, Alexander; Klym, Bogdan; Pochapsky, Yevhen

    2004-01-01

    Problems associated with polarimetric observations of low Earth orbit artificial satellites as important solar system objects are discussed. The instrumentation (the optical and mechanical parts, the control and drive electronics, and the application software) for performing such observations is also described

  17. Intensive client-centred occupational therapy in the home improves older adults' occupational performance. Results from a Danish randomized controlled trial

    DEFF Research Database (Denmark)

    Nielsen, Tove Lise; Andersen, Niels Trolle; Petersen, Kirsten Schultz

    2018-01-01

    Abstract Background: There is growing interest in enabling older adults’ occupational performance. We tested whether 11 weeks of intensive client-centred occupational therapy (ICC-OT) was superior to usual practice in improving the occupational performance of home-dwelling older adults. Methods...... randomised to receive either a maximum 22 sessions of occupation-based ICC-OT (N = 59) or to receive usual practice with a maximum three sessions of occupational therapy (N = 60). The primary outcome was self-rated occupational performance assessed with the Canadian Occupational Performance Measure (COPM...... significant (95% confidence interval 0.50 to 2.02), t-test: p = 0.001. Conclusions: ICC-OT improved older adults’ occupational performance more effectively than usual practice. This result may benefit older adults and support programmatic changes....

  18. Centre for Political and

    African Journals Online (AJOL)

    user

    and definitions will be published and the data translated into the official ... The Centre provides a terminological and subject-related service to lecturers and ... postgraduate students in international politics, political studies and .... obtain financial contributions (cf. .... making of authoritative and enforceable rules (laws) for.

  19. Implementing Responsibility Centre Budgeting

    Science.gov (United States)

    Vonasek, Joseph

    2011-01-01

    Recently, institutes of higher education (universities) have shown a renewed interest in organisational structures and operating methodologies that generate productivity and innovation; responsibility centre budgeting (RCB) is one such process. This paper describes the underlying principles constituting RCB, its origin and structural elements, and…

  20. Fuel cycle centres

    International Nuclear Information System (INIS)

    Hagen, M.

    1977-01-01

    The concept of co-locating and integrating fuel cycle facilities at one site is discussed. This concept offers considerable advantages, especially in minimizing the amount of radioactive material to be transported on public roads. Safeguards and physical protection as relating to such an integrated system of facilities are analysed in detail, also industrial and commercial questions. An overall risk-benefit evaluation turns out to be in favour of fuel cycle centres. These centres seem to be specifically attractive with regard to the back end of the fuel cycle, including on-site disposal of radioactive wastes. The respective German approach is presented as an example. Special emphasis is given to the site selection procedures in this case. Time scale and cost for the implementation of this concept are important factors to be looked at. Since participation of governmental institutions in these centres seems to be indispensable their respective roles as compared to industry must be clearly defined. The idea of adjusting fuel cycle centres to regional rather than national use might be an attractive option, depending on the specific parameters in the region, though results of existing multinational ventures are inconclusive in this respect. Major difficulties might be expected e.g. because of different national safety regulations and standards as well as commercial conditions among partner countries. Public acceptance in the host country seems to be another stumbling block for the realization of this type of multinational facilities

  1. Budapest Training Technology Centre.

    Science.gov (United States)

    Budapest Training Technology Centre (Hungary).

    The Budapest Training Technology Centre (BTTC) grew out of a 1990 agreement calling for Great Britain to help Hungary develop and implement open and flexible training methods and technology-based training to support the labor force development and vocational training needs resulting from Hungary's transition to a market economy. The BTTC would be…

  2. Official Centre Hospitality

    International Development Research Centre (IDRC) Digital Library (Canada)

    Sylvain Dufour

    Approved by the Management Executive Committee. - 1 -. Version 3.1.0 effective 2017-06-28. Official Centre Hospitality. 1. Objective. 2. Application. 3. Definitions. 4. Roles and Responsibilities. 5. Authorization. 6. Consultants and Contractors. 7. Reimbursement. 1. Objective. To define the circumstances under which ...

  3. Academic Drug Discovery Centres

    DEFF Research Database (Denmark)

    Kirkegaard, Henriette Schultz; Valentin, Finn

    2014-01-01

    Academic drug discovery centres (ADDCs) are seen as one of the solutions to fill the innovation gap in early drug discovery, which has proven challenging for previous organisational models. Prior studies of ADDCs have identified the need to analyse them from the angle of their economic...

  4. ATLAS Visitors Centre

    CERN Multimedia

    claudia Marcelloni

    2009-01-01

    ATLAS Visitors Centre has opened its shiny new doors to the public. Officially launched on Monday February 23rd, 2009, the permanent exhibition at Point 1 was conceived as a tour resource for ATLAS guides, and as a way to preserve the public’s opportunity to get a close-up look at the experiment in action when the cavern is sealed.

  5. Satellite communications: possibilities and problems

    International Nuclear Information System (INIS)

    Hine, M.

    1986-01-01

    Communication links via satellites are becoming available in Europe, both as part of the development of the telephone system and as special services aimed at data traffic. They offer the possibility of speeds between 50 kb/s and 2 Mb/s, without the problems and long term commitments of long distance land lines. Such links are provided by the PTT's as circuits which can be booked for variable periods, and have error rates which can be very low and well controlled. Problems in networking can arise from the satellite delay, particularly if errors occur in the local connections, and from the leased circuit and tariff philosophies of the PTT's. (Auth.)

  6. IMPLEMENTATION OF AERONAUTICAL LOCAL SATELLITE AUGMENTATION SYSTEM

    Directory of Open Access Journals (Sweden)

    Stojce Ilcev

    2011-03-01

    Full Text Available Abstract. This paper introduces development and implementation of new Local Satellite AugmentationSystem as an integration component of the Regional Satellite Augmentation System (RSAS employingcurrent and new Satellite Communications, Navigation and Surveillance (CNS for improvement of the AirTraffic Control (ATC and Air Traffic Management (ATM and for enhancement safety systems includingtransport security and control of flights in all stages, airport approaching, landing, departures and allmovements over airport surface areas. The current first generation of the Global Navigation Satellite SystemGNSS-1 applications are represented by fundamental military solutions for Position, Velocity and Time ofthe satellite navigation and determination systems such as the US GPS and Russian GLONASS (Former-USSR requirements, respectively. The establishment of Aeronautical CNS is also discussed as a part ofGlobal Satellite Augmentation Systems of GPS and GLONASS systems integrated with existing and futureRSAS and LSAS in airports areas. Specific influence and factors related to the Comparison of the Currentand New Aeronautical CNS System including the Integration of RSAS and GNSS solutions are discussedand packet of facts is determined to maximize the new satellite Automatic Dependent Surveillance System(ADSS and Special Effects of the RSAS Networks. The possible future integration of RSAS and GNSS andthe common proposal of the satellite Surface Movement Guidance and Control are presented in thechangeless ways as of importance for future enfacements of ATC and ATM for any hypothetical airportinfrastructure.Keywords: ADSS, ATC, ATM, CNS, GSAS, LRAS, RSAS, SMGC, Special Effects of RSAS.

  7. Satellite Cell Self-Renewal.

    Science.gov (United States)

    Giordani, Lorenzo; Parisi, Alice; Le Grand, Fabien

    2018-01-01

    Adult skeletal muscle is endowed with regenerative potential through partially recapitulating the embryonic developmental program. Upon acute injury or in pathological conditions, quiescent muscle-resident stem cells, called satellite cells, become activated and give rise to myogenic progenitors that massively proliferate, differentiate, and fuse to form new myofibers and restore tissue functionality. In addition, a proportion of activated cells returns back to quiescence and replenish the pool of satellite cells in order to maintain the ability of skeletal muscle tissue to repair. Self-renewal is the process by which stem cells divide to make more stem cells to maintain the stem cell population throughout life. This process is controlled by cell-intrinsic transcription factors regulated by cell-extrinsic signals from the niche and the microenvironment. This chapter provides an overview about the general aspects of satellite cell biology and focuses on the cellular and molecular aspects of satellite cell self-renewal. To date, we are still far from understanding how a very small proportion of the satellite cell progeny maintain their stem cell identity when most of their siblings progress through the myogenic program to construct myofibers. © 2018 Elsevier Inc. All rights reserved.

  8. The DIY Digital Medical Centre.

    Science.gov (United States)

    Timmis, James Kenneth; Timmis, Kenneth

    2017-09-01

    Healthcare systems worldwide are confronted with major economic, organizational and logistical challenges. Historic evolution of health care has led to significant healthcare sector fragmentation, resulting in systemic inefficiencies and suboptimal resource exploitation. To attain a sustainable healthcare model, fundamental, system-wide improvements that effectively network, and ensure fulfilment of potential synergies between sectors, and include and facilitate coherent strategic planning and organisation of healthcare infrastructure are needed. Critically, they must be specifically designed to sustainably achieve peak performance within the current policy environment for cost-control, and efficiency and quality improvement for service delivery. We propose creation of a new healthcare cluster, to be embedded in existing healthcare systems. It consists of (i) local 24/7 walk-in virtually autonomous do-it-yourself Digital Medical Centres performing routine diagnosis, monitoring, prevention, treatment and standardized documentation and health outcome assessment/reporting, which are online interfaced with (ii) regional 24/7 eClinician Centres providing on-demand clinical supervision/assistance to Digital Medical Centre patients. Both of these are, in turn, online interfaced with (iii) the National Clinical Informatics Centre, which houses the national patient data centre (cloud) and data analysis units that conduct patient- and population-level, personalized and predictive(-medicine) intervention optimization analyses. The National Clinical Informatics Centre also interfaces with biomedical research and prioritizes and accelerates the translation of new discoveries into clinical practice. The associated Health Policy Innovation and Evaluation Centre rapidly integrates new findings with health policy/regulatory discussions. This new cluster would synergistically link all health system components in a circular format, enable not only access by all arms of the health

  9. Satellite Altimeters and Gravimeters as Proxy of the Indonesian Throughflow

    Science.gov (United States)

    Susanto, R. D.; Song, Y. T.

    2014-12-01

    The Indonesian Throughflow (ITF), the only pathway for interocean exchange between the Pacific to the Indian Ocean, plays an important role in global ocean circulation and climate. Yet, continuous ITF measurement is difficult and expensive. We demonstrate a plausible approach to derive the ITF transport proxy using satellite altimetry sea surface height (SSH), gravimetry ocean bottom pressure (OBP) data, in situ measurements from the Makassar Strait from 1996-1998 and 2004-2009, and a theoretical formulation. We first identified the optimal locations in the Pacific and Indian Ocean based on the optimal correlation between the ITF transport through the Makassar Strait and the pressure gradients, represented by the SSH and OBP differences between the Pacific and Indian Oceans at a 1° x 1° horizontal resolution. These geographical locations (centred at off-equatorial in the western Pacific Ocean and centred at along the equator in the eastern Indian Ocean) that control the strength and variability of the ITF transport in the Makassar Strait differ from early studies. The proxy time series follow the observation time series quite well, resolving the intraseasonal, monsoonal, and interannual signals with the 1993-2011 annual mean proxy transport of 11.6 ± 3.2 Sv. Our formulation provides a continuous approach to derive the ITF proxy as long as the satellite data are available. Such a continuous record would be difficult to achieve by in situ measurements alone due to logistical and financial challenges. Ideally, the proxy can be used to complement or fill in the gaps of the observations for a continuous ITF proxy for better understanding the ocean climate and validating ocean circulation models.

  10. Benefits of China's efforts in gaseous pollutant control indicated by the bottom-up emissions and satellite observations 2000-2014

    Science.gov (United States)

    Xia, Yinmin; Zhao, Yu; Nielsen, Chris P.

    2016-07-01

    To evaluate the effectiveness of national air pollution control policies, the emissions of SO2, NOX, CO and CO2 in China are estimated using bottom-up methods for the most recent 15-year period (2000-2014). Vertical column densities (VCDs) from satellite observations are used to test the temporal and spatial patterns of emissions and to explore the ambient levels of gaseous pollutants across the country. The inter-annual trends in emissions and VCDs match well except for SO2. Such comparison is improved with an optimistic assumption in emission estimation that the emission standards for given industrial sources issued after 2010 have been fully enforced. Underestimation of emission abatement and enhanced atmospheric oxidization likely contribute to the discrepancy between SO2 emissions and VCDs. As suggested by VCDs and emissions estimated under the assumption of full implementation of emission standards, the control of SO2 in the 12th Five-Year Plan period (12th FYP, 2011-2015) is estimated to be more effective than that in the 11th FYP period (2006-2010), attributed to improved use of flue gas desulfurization in the power sector and implementation of new emission standards in key industrial sources. The opposite was true for CO, as energy efficiency improved more significantly from 2005 to 2010 due to closures of small industrial plants. Iron & steel production is estimated to have had particularly strong influence on temporal and spatial patterns of CO. In contrast to fast growth before 2011 driven by increased coal consumption and limited controls, NOX emissions decreased from 2011 to 2014 due to the penetration of selective catalytic/non-catalytic reduction systems in the power sector. This led to reduced NO2 VCDs, particularly in relatively highly polluted areas such as the eastern China and Pearl River Delta regions. In developed areas, transportation is playing an increasingly important role in air pollution, as suggested by the increased ratio of NO2 to SO

  11. The Scandinavian Propaten(®) trial - 1-year patency of PTFE vascular prostheses with heparin-bonded luminal surfaces compared to ordinary pure PTFE vascular prostheses - a randomised clinical controlled multi-centre trial.

    Science.gov (United States)

    Lindholt, J S; Gottschalksen, B; Johannesen, N; Dueholm, D; Ravn, H; Christensen, E D; Viddal, B; Flørenes, T; Pedersen, G; Rasmussen, M; Carstensen, M; Grøndal, N; Fasting, H

    2011-05-01

    To compare 1-year potencies' of heparin-bonded PTFE [(Hb-PTFE) (Propaten(®))] grafts with those of ordinary polytetraflouroethylene (PTFE) grafts in a blinded, randomised, clinically controlled, multi-centre study. Eleven Scandinavian centres enrolled 569 patients with chronic functional or critical lower limb ischaemia who were scheduled to undergo femoro-femoral bypass or femoro-poplitaeal bypass. The patients were randomised 1:1 stratified by centre. Patency was assessed by duplex ultrasound scanning. A total of 546 patients (96%) completed the study with adequate follow-up. Perioperative bleeding was, on average, 370 ml with PTFE grafts and 399 ml with Heparin-bonded PTFE grafts (p = 0.32). Overall, primary patency after 1 year was 86.4% for Hb-PTFE grafts and 79.9% for PTFE grafts (OR = 0.627, 95% CI: 0.398; 0.989, p = 0.043). Secondary patency was 88% in Hb-PTFE grafts and 81% in PTFE grafts (OR = 0.569 (0.353; 0.917, p = 0.020)). Subgroup analyses revealed that significant reduction in risk (50%) was observed when Hb-PTFE was used for femoro-poplitaeal bypass (OR = 0.515 (0.281; 0.944, p = 0.030)), and a significant reduction in risk (50%) was observed with Hb-PTFE in cases with critical ischaemia (OR = 0.490 (0.249; 0.962, p = 0.036)). The Hb-PTFE graft significantly reduced the overall risk of primary graft failure by 37%. Risk reduction was 50% in femoro-poplitaeal bypass cases and in cases with critical ischaemia. Copyright © 2011. Published by Elsevier Ltd.

  12. A statistical rain attenuation prediction model with application to the advanced communication technology satellite project. 3: A stochastic rain fade control algorithm for satellite link power via non linear Markow filtering theory

    Science.gov (United States)

    Manning, Robert M.

    1991-01-01

    The dynamic and composite nature of propagation impairments that are incurred on Earth-space communications links at frequencies in and above 30/20 GHz Ka band, i.e., rain attenuation, cloud and/or clear air scintillation, etc., combined with the need to counter such degradations after the small link margins have been exceeded, necessitate the use of dynamic statistical identification and prediction processing of the fading signal in order to optimally estimate and predict the levels of each of the deleterious attenuation components. Such requirements are being met in NASA's Advanced Communications Technology Satellite (ACTS) Project by the implementation of optimal processing schemes derived through the use of the Rain Attenuation Prediction Model and nonlinear Markov filtering theory.

  13. The EPFL Plasma Physics Research Centre

    International Nuclear Information System (INIS)

    2001-01-01

    The Plasma Physics Research Centre (CRPP) is a non-departmental unit of the EPFL, and currently employs about 130 people, about 105 on the EPFL site and the rest at the Paul Scherrer Institute, PSI, in Villigen, Switzerland. The CRPP is a National Competence Centre in the field of Plasma Physics. In addition to plasma physics teaching, its missions are primarily the pursuit of scientific research in the field of controlled fusion within the framework of the EURATOM-Swiss Confederation Association and the development of its expertise as well as technology transfer in the field of materials research. As the body responsible for all scientific work on controlled fusion in Switzerland, the CRPP plays a national role of international significance. This document of 6 pages presents the explanation of the Plasma Physics Research Centre' activities (CRPP). (author)

  14. Real-time monitoring of seismic data using satellite telemetry

    Directory of Open Access Journals (Sweden)

    L. Merucci

    1997-06-01

    Full Text Available This article describes the ARGO Satellite Seismic Network (ARGO SSN as a reliable system for monitoring, collection, visualisation and analysis of seismic and geophysical low-frequency data, The satellite digital telemetry system is composed of peripheral geophysical stations, a centraI communications node (master sta- tion located in CentraI Italy, and a data collection and processing centre located at ING (Istituto Nazionale di Geofisica, Rome. The task of the peripheral stations is to digitalise and send via satellite the geophysical data collected by the various sensors to the master station. The master station receives the data and forwards them via satellite to the ING in Rome; it also performs alI the monitoring functions of satellite communications. At the data collection and processing centre of ING, the data are received and analysed in real time, the seismic events are identified and recorded, the low-frequency geophysical data are stored. In addition, the generaI sta- tus of the satellite network and of each peripheral station connected, is monitored. The procedure for analysjs of acquired seismic signals allows the automatic calculation of local magnitude and duration magnitude The communication and data exchange between the seismic networks of Greece, Spain and Italy is the fruit of a recent development in the field of technology of satellite transmission of ARGO SSN (project of European Community "Southern Europe Network for Analysis of Seismic Data"

  15. Family-centred music therapy to promote social engagement in young children with severe autism spectrum disorder: a randomized controlled study.

    Science.gov (United States)

    Thompson, G A; McFerran, K S; Gold, C

    2014-11-01

    Limited capacity for social engagement is a core feature of autism spectrum disorder (ASD), often evident early in the child's development. While these skills are difficult to train, there is some evidence that active involvement in music-making provides unique opportunities for social interaction between participants. Family-centred music therapy (FCMT) endeavours to support social engagement between child and parent within active music-making, yet the extent of benefits provided is unknown. This study investigated the impacts of FCMT on social engagement abilities. Twenty-three children (36-60 months) with severe ASD received either 16 weeks of FCMT in addition to their early intervention programmes (n = 12), or their early intervention programme only (n = 11). Change in social engagement was measured with standardized parent-report assessments, parent interviews and clinician observation. Intention-to-treat analysis for the Vineland Social Emotional Early Childhood Scale indicated a significant effect in favour of FCMT. Thematic qualitative analysis of the parent interviews showed that the parent-child relationship grew stronger. FCMT improves social interactions in the home and community and the parent-child relationship, but not language skills or general social responsiveness. This study provides preliminary support for the use of FCMT to promote social engagement in children with severe ASD. © 2013 John Wiley & Sons Ltd.

  16. Failure analysis of satellite subsystems to define suitable de-orbit devices

    Science.gov (United States)

    Palla, Chiara; Peroni, Moreno; Kingston, Jennifer

    2016-11-01

    Space missions in Low Earth Orbit (LEO) are severely affected by the build-up of orbital debris. A key practice, to be compliant with IADC (Inter-Agency Space Debris Coordination Committee) mitigation guidelines, is the removal of space systems that interfere with the LEO region not later than 25 years after the End of Mission. It is important to note that the current guidelines are not generally legally binding, even if different Space Agencies are now looking at the compliance for their missions. If the guidelines will change in law, it will be mandatory to have a postmission disposal strategy for all satellites, including micro and smaller classes. A potential increased number of these satellites is confirmed by different projections, in particular in the commercial sector. Micro and smaller spacecraft are, in general, not provided with propulsion capabilities to achieve a controlled re-entry, so they need different de-orbit disposal methods. When considering the utility of different debris mitigation methods, it is useful to understand which spacecraft subsystems are most likely to fail and how this may affect the operation of a de-orbit system. This also helps the consideration of which components are the most relevant or should be redundant depending on the satellite mass class. This work is based on a sample of LEO and MEO satellites launched between January 2000 and December 2014 with mass lower than 1000 kg. Failure analysis of satellite subsystems is performed by means of the Kaplan-Meier survival analysis; the parametric fits are conducted with Weibull distributions. The study is carried out by using the satellite database SpaceTrak™ which provides anomalies, failures, and trends information for spacecraft subsystems and launch vehicles. The database identifies five states for each satellite subsystem: three degraded states, one fully operational state, and one failed state (complete failure). The results obtained can guide the identification of the

  17. Elderly Care Centre

    Science.gov (United States)

    Wagiman, Aliani; Haja Bava Mohidin, Hazrina; Ismail, Alice Sabrina

    2016-02-01

    The demand for elderly centre has increased tremendously abreast with the world demographic change as the number of senior citizens rose in the 21st century. This has become one of the most crucial problems of today's era. As the world progress into modernity, more and more people are occupied with daily work causing the senior citizens to lose the care that they actually need. This paper seeks to elucidate the best possible design of an elderly care centre with new approach in order to provide the best service for them by analysing their needs and suitable activities that could elevate their quality of life. All these findings will then be incorporated into design solutions so as to enhance the living environment for the elderly especially in Malaysian context.

  18. International Data Centre (IDC)

    International Nuclear Information System (INIS)

    Johansson, P.

    2002-01-01

    The presentation outlines the International Data Centre (Indc) mission, objective and historical background. The Indc progressive commissioning and organizational plans are presented on charts. The IMS stations providing data to Indc operations and the global communication infrastructure are plotted on world maps. The various types of IMS data are thus listed as seismic, hydroacoustic, infrasound and radionuclide. Finally Indc products and services together with its main achievements are listed

  19. Meteorological satellite systems

    CERN Document Server

    Tan, Su-Yin

    2014-01-01

    “Meteorological Satellite Systems” is a primer on weather satellites and their Earth applications. This book reviews historic developments and recent technological advancements in GEO and polar orbiting meteorological satellites. It explores the evolution of these remote sensing technologies and their capabilities to monitor short- and long-term changes in weather patterns in response to climate change. Satellites developed by various countries, such as U.S. meteorological satellites, EUMETSAT, and Russian, Chinese, Japanese and Indian satellite platforms are reviewed. This book also discusses international efforts to coordinate meteorological remote sensing data collection and sharing. This title provides a ready and quick reference for information about meteorological satellites. It serves as a useful tool for a broad audience that includes students, academics, private consultants, engineers, scientists, and teachers.

  20. Theory of geostationary satellites

    CERN Document Server

    Zee, Chong-Hung

    1989-01-01

    Geostationary or equatorial synchronous satellites are a daily reminder of our space efforts during the past two decades. The nightly television satellite weather picture, the intercontinental telecommunications of television transmissions and telephone conversations, and the establishrnent of educational programs in remote regions on Earth are constant reminders of the presence of these satellites. As used here, the term 'geo­ stationary' must be taken loosely because, in the long run, the satellites will not remain 'stationary' with respect to an Earth-fixed reference frame. This results from the fact that these satellites, as is true for all satellites, are incessantly subject to perturbations other than the central-body attraction of the Earth. Among the more predominant pertur­ bations are: the ellipticity of the Earth's equator, the Sun and Moon, and solar radiation pressure. Higher harmonics of the Earth's potential and tidal effects also influence satellite motion, but they are of second­ order whe...

  1. Historical centres: changing definitions

    Directory of Open Access Journals (Sweden)

    Roberta Lazzarotti

    2014-02-01

    Full Text Available Since the end of the Second World War, the architectural and planning culture has been showing a fluctuating attention to the theme of historical centres and their enhancement. First of all this uneven progress explains the difficulty to reach a homogeneous definition and this is still lacking. During a long phase of this period, the historical parts of the town were considered as objects to be preserved in an integral way, as urban monuments. This is mostly due to the high symbolic value of these settlements, that represent fundamental landmarks. Identity building and empowerment of local communities are indispensable conditions for any development programme, especially in the case of centres or other historic environments at risk of abandonment. The progressive evolution of this concept brings awareness of the impossibility of separating – either in analytical or in planning terms ­ historical centres from their urban and territorial contexts, which are linked by mutual, deep relationships. This article attempts to retrace the steps signaled by the publication of international documents and conventions, from the Charter of Gubbio (1960 to the Charter of Krakow and the European Landscape Convention (2000; they obviously represent particular points of view, not exhaustive of the richness of the positions in the debate, but extremely significant in terms of diffusion and consensus.

  2. Mobilisation of satellite cells following ischaemia and reperfusion in ...

    African Journals Online (AJOL)

    Objective. To describe the morphological and morphometric features of activated skeletal muscle satellite cells in primates, using an ischaemic reperfusion model. Setting. The study was undertaken at the Biomedical Resource Centre and the Electron Microscopy Unit of the University of KwaZulu-Natal. Interventions.

  3. Spin motion determination of the Envisat satellite through laser ranging measurements from a single pass measured by a single station

    Science.gov (United States)

    Pittet, Jean-Noël; Šilha, Jiří; Schildknecht, Thomas

    2018-02-01

    The Satellite Laser Ranging (SLR) technology is used to accurately determine the position of space objects equipped with so-called retro-reflectors or retro-reflector arrays (RRA). This type of measurement allows to measure the range to the spacecraft with high precision, which leads to determination of very accurate orbits for these targets. Non-active spacecraft, which are not attitude controlled any longer, tend to start to spin or tumble under influence of the external and internal torques and forces. If the return signal is measured for a non-spherical non-active rotating object, the signal in the range residuals with respect to the reference orbit is more complex. For rotating objects the return signal shows an oscillating pattern or patterns caused by the RRA moving around the satellite's centre of mass. This behaviour is projected onto the radial component measured by the SLR. In our work, we demonstrate how the SLR ranging technique from one sensor to a satellite equipped with a RRA can be used to precisely determine its spin motion during one passage. Multiple SLR measurements of one target over time allow to accurately monitor spin motion changes which can be further used for attitude predictions. We show our solutions of the spin motion determined for the non-active ESA satellite Envisat obtained from measurements acquired during years 2013-2015 by the Zimmerwald SLR station, Switzerland. All the necessary parameters are defined for our own so-called point-like model which describes the motion of a point in space around the satellite centre of mass.

  4. Protocol for the ProFHER (PROximal Fracture of the Humerus: Evaluation by Randomisation trial: a pragmatic multi-centre randomised controlled trial of surgical versus non-surgical treatment for proximal fracture of the humerus in adults

    Directory of Open Access Journals (Sweden)

    Maffulli Nicola

    2009-11-01

    Full Text Available Abstract Background Proximal humeral fractures, which occur mainly in older adults, account for approximately 4 to 5% of all fractures. Approximately 40% of these fractures are displaced fractures involving the surgical neck. Management of this group of fractures is often challenging and the outcome is frequently unsatisfactory. In particular it is not clear whether surgery gives better outcomes than non-surgical management. Currently there is much variation in the use of surgery and a lack of good quality evidence to inform this decision. Methods/Design We aim to undertake a pragmatic UK-based multi-centre randomised controlled trial evaluating the effectiveness and cost-effectiveness of surgical versus standard non-surgical treatment for adults with an acute closed displaced fracture of the proximal humerus with involvement of the surgical neck. The choice of surgical intervention is left to the surgeon, who must use techniques that they are fully experienced with. This will avoid 'learning curve' problems. We will promote good standards of non-surgical care, similarly insisting on care-provider competence, and emphasize the need for comparable provision of rehabilitation for both groups of patients. We aim to recruit 250 patients from a minimum of 18 NHS trauma centres throughout the UK. These patients will be followed-up for 2 years. The primary outcome is the Oxford Shoulder Score, which will be collected via questionnaires completed by the trial participants at 6, 12 and 24 months. This is a 12-item condition-specific questionnaire providing a total score based on the person's subjective assessment of pain and activities of daily living impairment. We will also collect data for other outcomes, including general health measures and complications, and for an economic evaluation. Additionally, we plan a systematic collection of reasons for non-inclusion of eligible patients who were not recruited into the trial, and their baseline

  5. Environmental monitoring of the Cea Valduc centre

    International Nuclear Information System (INIS)

    Guetat, Ph.; Jaskula, L.

    2010-01-01

    This paper describes the main features of the environmental control in the vicinity of the CEA Valduc centre, explains the site specific characteristics, the surveillance policy, and some historical elements about tritium atmospheric release. Some levels of activities are given, corresponding to an exposure level below 0.02% of natural irradiation. (author)

  6. Description of the Nuclear Training Centre

    International Nuclear Information System (INIS)

    Wagadarikar, V.K.

    1974-01-01

    The Department of Atomic Energy, Government of India has developed an on-going programme for constructing and operating heavy water moderated, natural uranium fuelled power stations of the CANDU-type. With the view to train personnel required for operation and maintenance of these stations, a Nuclear Training Centre has been set up at the site of the Rajasthan Atomic Power Station. A description of the nuclear training centre with its facilities is given. The training programme for engineers, operators, mechanical, electrical and control maintainers etc. is given in detail, along with the actual syllabi for respective courses. Examples of the typical field check list are provided. (K.B.)

  7. Toward the Public Dividend: A Report on Satellite Telecommunications and the Public Interest Satellite Association.

    Science.gov (United States)

    McGraw, Walter

    This report points out that the communications satellite appears to be on its way to becoming one of the most dominant and controlling technologies of our time, and this requires that a new evaluation be made of our entire communications process. The first section of the report discusses many aspects of the history of satellites, including the…

  8. Fabrication of single optical centres in diamond-a review

    International Nuclear Information System (INIS)

    Orwa, J.O.; Greentree, A.D.; Aharonovich, I.; Alves, A.D.C.; Van Donkelaar, J.; Stacey, A.; Prawer, S.

    2010-01-01

    Colour centres in diamond are rapidly becoming one of the leading platforms for solid-state quantum information processing applications. This is due in large part to the remarkable properties of the nitrogen-vacancy colour centre. From initial demonstrations of room-temperature single photon generation and spin single spin readout and quantum control, diamond nanocrystals are also finding application in magnetometry and biosensing. This review discusses the state of the art in the creation of isolated and small ensembles of optically active diamond defect centres, including nitrogen and nickel-related centres.

  9. Satellite switched FDMA advanced communication technology satellite program

    Science.gov (United States)

    Atwood, S.; Higton, G. H.; Wood, K.; Kline, A.; Furiga, A.; Rausch, M.; Jan, Y.

    1982-01-01

    The satellite switched frequency division multiple access system provided a detailed system architecture that supports a point to point communication system for long haul voice, video and data traffic between small Earth terminals at Ka band frequencies at 30/20 GHz. A detailed system design is presented for the space segment, small terminal/trunking segment at network control segment for domestic traffic model A or B, each totaling 3.8 Gb/s of small terminal traffic and 6.2 Gb/s trunk traffic. The small terminal traffic (3.8 Gb/s) is emphasized, for the satellite router portion of the system design, which is a composite of thousands of Earth stations with digital traffic ranging from a single 32 Kb/s CVSD voice channel to thousands of channels containing voice, video and data with a data rate as high as 33 Mb/s. The system design concept presented, effectively optimizes a unique frequency and channelization plan for both traffic models A and B with minimum reorganization of the satellite payload transponder subsystem hardware design. The unique zoning concept allows multiple beam antennas while maximizing multiple carrier frequency reuse. Detailed hardware design estimates for an FDMA router (part of the satellite transponder subsystem) indicate a weight and dc power budget of 353 lbs, 195 watts for traffic model A and 498 lbs, 244 watts for traffic model B.

  10. DGNB certified Healthcare Centres

    DEFF Research Database (Denmark)

    Brunsgaard, Camilla; Larsen, Tine Steen

    2015-01-01

    for sustainability and wants a certification. This research investigates the decision‐making and design process (DMaDP) behind four DGNB certified Healthcare Centres (HCC) in Northern Jutland in Denmark. In general, knowledge about the DMaDP is important. However it is important to know what part DGNB plays...... a dialog about DGNB and energy concept is important even before anyone start sketching. Experiences with the different approaches will be further outlined in the paper.Future research has the intention to collect further knowledge about DGNB and DMaDP in practise. This project was limited to Healthcare...

  11. Town Centre Redevelopment Strategies

    DEFF Research Database (Denmark)

    Vagnby, Bo Hellisen

    After many years of urban growth Danish downtowns are facing some important choices. Shall the stake one-sidedly be on the town centres as driving forces for growth and 'city marketing', or do they still have a role to play in a broader socio-economic context? In the paper we look back on eight...... as slum clearence and urban renewal. To a certain extent parallels are drawn to international experiences, especially where these are of such a nature that they can be assumed transferred to Danish connctions. Conclusively, the strategies are discussed in the light of the turn of Danish urban planning...

  12. Communication satellite applications

    Science.gov (United States)

    Pelton, Joseph N.

    The status and future of the technologies, numbers and services provided by communications satellites worldwide are explored. The evolution of Intelsat satellites and the associated earth terminals toward high-rate all-digital telephony, data, facsimile, videophone, videoconferencing and DBS capabilities are described. The capabilities, services and usage of the Intersputnik, Eutelsat, Arabsat and Palapa systems are also outlined. Domestic satellite communications by means of the Molniya, ANIK, Olympus, Intelsat and Palapa spacecraft are outlined, noting the fast growth of the market and the growing number of different satellite manufacturers. The technical, economic and service definition issues surrounding DBS systems are discussed, along with presently operating and planned maritime and aeronautical communications and positioning systems. Features of search and rescue and tracking, data, and relay satellite systems are summarized, and services offered or which will be offered by every existing or planned communication satellite worldwide are tabulated.

  13. Study Protocol. IDUS -- Instrumental delivery & ultrasound. A multi-centre randomised controlled trial of ultrasound assessment of the fetal head position versus standard care as an approach to prevent morbidity at instrumental delivery

    LENUS (Irish Health Repository)

    Murphy, Deirdre J

    2012-09-13

    AbstractBackgroundInstrumental deliveries are commonly performed in the United Kingdom and Ireland, with rates of 12 – 17% in most centres. Knowing the exact position of the fetal head is a pre-requisite for safe instrumental delivery. Traditionally, diagnosis of the fetal head position is made on transvaginal digital examination by delineating the suture lines of the fetal skull and the fontanelles. However, the accuracy of transvaginal digital examination can be unreliable and varies between 20% and 75%. Failure to identify the correct fetal head position increases the likelihood of failed instrumental delivery with the additional morbidity of sequential use of instruments or second stage caesarean section. The use of ultrasound in determining the position of the fetal head has been explored but is not part of routine clinical practice.Methods\\/DesignA multi-centre randomised controlled trial is proposed. The study will take place in two large maternity units in Ireland with a combined annual birth rate of 13,500 deliveries. It will involve 450 nulliparous women undergoing instrumental delivery after 37 weeks gestation. The main outcome measure will be incorrect diagnosis of the fetal head position. A study involving 450 women will have 80% power to detect a 10% difference in the incidence of inaccurate diagnosis of the fetal head position with two-sided 5% alpha.DiscussionIt is both important and timely to evaluate the use of ultrasound to diagnose the fetal head position prior to instrumental delivery before routine use can be advocated. The overall aim is to reduce the incidence of incorrect diagnosis of the fetal head position prior to instrumental delivery and improve the safety of instrumental deliveries.Trial registrationCurrent Controlled Trials ISRCTN72230496

  14. Study Protocol. IDUS – Instrumental delivery & ultrasound. A multi-centre randomised controlled trial of ultrasound assessment of the fetal head position versus standard care as an approach to prevent morbidity at instrumental delivery

    Directory of Open Access Journals (Sweden)

    Murphy Deirdre J

    2012-09-01

    Full Text Available Abstract Background Instrumental deliveries are commonly performed in the United Kingdom and Ireland, with rates of 12 – 17% in most centres. Knowing the exact position of the fetal head is a pre-requisite for safe instrumental delivery. Traditionally, diagnosis of the fetal head position is made on transvaginal digital examination by delineating the suture lines of the fetal skull and the fontanelles. However, the accuracy of transvaginal digital examination can be unreliable and varies between 20% and 75%. Failure to identify the correct fetal head position increases the likelihood of failed instrumental delivery with the additional morbidity of sequential use of instruments or second stage caesarean section. The use of ultrasound in determining the position of the fetal head has been explored but is not part of routine clinical practice. Methods/Design A multi-centre randomised controlled trial is proposed. The study will take place in two large maternity units in Ireland with a combined annual birth rate of 13,500 deliveries. It will involve 450 nulliparous women undergoing instrumental delivery after 37 weeks gestation. The main outcome measure will be incorrect diagnosis of the fetal head position. A study involving 450 women will have 80% power to detect a 10% difference in the incidence of inaccurate diagnosis of the fetal head position with two-sided 5% alpha. Discussion It is both important and timely to evaluate the use of ultrasound to diagnose the fetal head position prior to instrumental delivery before routine use can be advocated. The overall aim is to reduce the incidence of incorrect diagnosis of the fetal head position prior to instrumental delivery and improve the safety of instrumental deliveries. Trial registration Current Controlled Trials ISRCTN72230496

  15. Satellite services system overview

    Science.gov (United States)

    Rysavy, G.

    1982-01-01

    The benefits of a satellite services system and the basic needs of the Space Transportation System to have improved satellite service capability are identified. Specific required servicing equipment are discussed in terms of their technology development status and their operative functions. Concepts include maneuverable television systems, extravehicular maneuvering unit, orbiter exterior lighting, satellite holding and positioning aid, fluid transfer equipment, end effectors for the remote manipulator system, teleoperator maneuvering system, and hand and power tools.

  16. Mochovce waste treatment centre

    International Nuclear Information System (INIS)

    Sedliak, D.; Endrody, J.

    2000-01-01

    The first unit of the Mochovce NPP (WWER 440 MW) was put in a test operation in October 1998. The second unit with the same power output was put in the test operation in March 2000. The Nuclear Regulatory Authority of the Slovak Republic in its Decision No. 318/98 of 28 October 1998, by which an agreement with the operation of the Unit 1 of the Mochovce. Nuclear Power Plant was issued, requires to start the construction of the Liquid Radioactive Waste Treatment Centre until January 2004. The subject of this presentation is a system description of the Liquid Radioactive Waste (LRW) management in the Mochovce NPP. The initial part is dedicated to a short description of the radioactive waste management legislation requirements. Then the presentation continues with an information about the LRW production in the Mochovce NPP, LRW sources, chemical and radiochemical attributes, description of storage. The presentation also provides real values of its production in a comparison with the design data. The LRW production minimization principles are also mentioned there. Another part deals with the basic requirements for the technology proposal of the liquid RW treatment, especially concerning the acceptance criteria at the Republic RW Repository Mochovce. The final part is devoted to a short description of the investment procedure principles - design preparation levels and a proposed construction schedule of the centre. (authors)

  17. The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis

    DEFF Research Database (Denmark)

    Saetre, Peter; Lundmark, Per; Wang, August

    2010-01-01

    Serotonin (5-hydroxytryptamin; 5-HT) alternations has since long been suspected in the pathophysiology of schizophrenia. Tryptophan hydroxylase (tryptophan 5-monooxygenase; TPH) is the rate-limiting enzyme in the biosynthesis of 5-HT, and sequence variation in intron 6 of the TPH1 gene has been...... associated with schizophrenia. The minor allele (A) of this polymorphism (A218C) is also more frequent in patients who have attempted suicide and individuals who died by suicide, than in healthy control individuals. In an attempt to replicate previous findings, five single nucleotide polymorphisms (SNPs......) were genotyped in 837 Scandinavian schizophrenia patients and 1,473 controls. Three SNPs spanning intron 6 and 7, including the A218C and A779C polymorphisms, were associated with schizophrenia susceptibility (P = 0.019). However there were no differences in allele frequencies of these loci between...

  18. The Effects of a Locally Developed mHealth Intervention on Delivery and Postnatal Care Utilization; A Prospective Controlled Evaluation among Health Centres in Ethiopia.

    Science.gov (United States)

    Shiferaw, Solomon; Spigt, Mark; Tekie, Michael; Abdullah, Muna; Fantahun, Mesganaw; Dinant, Geert-Jan

    2016-01-01

    Although there are studies showing that mobile phone solutions can improve health service delivery outcomes in the developed world, there is little empirical evidence that demonstrates the impact of mHealth interventions on key maternal health outcomes in low income settings. A non-randomized controlled study was conducted in the Amhara region, Ethiopia in 10 health facilities (5 intervention, 5 control) together serving around 250,000 people. Health workers in the intervention group received an android phone (3 phones per facility) loaded with an application that sends reminders for scheduled visits during antenatal care (ANC), delivery and postnatal care (PNC), and educational messages on dangers signs and common complaints during pregnancy. The intervention was developed at Addis Ababa University in Ethiopia. Primary outcomes were the percentage of women who had at least 4 ANC visits, institutional delivery and PNC visits at the health center after 12 months of implementation of the intervention. Overall 933 and 1037 women were included in the cross-sectional surveys at baseline and at follow-up respectively. In addition, the medical records of 1224 women who had at least one antenatal care visit were followed in the longitudinal study. Women who had their ANC visit in the intervention health centers were significantly more likely to deliver their baby in the same health center compared to the control group (43.1% versus 28.4%; Adjusted Odds Ratio (AOR): 1.98 (95%CI 1.53-2.55)). A significantly higher percentage of women who had ANC in the intervention group had PNC in the same health center compared to the control health centers (41.2% versus 21.1%: AOR: 2.77 (95%CI 2.12-3.61)). Our findings demonstrated that a locally customized mHealth application during ANC can significantly improve delivery and postnatal care service utilization possibly through positively influencing the behavior of health workers and their clients.

  19. The Effects of a Locally Developed mHealth Intervention on Delivery and Postnatal Care Utilization; A Prospective Controlled Evaluation among Health Centres in Ethiopia.

    Directory of Open Access Journals (Sweden)

    Solomon Shiferaw

    Full Text Available Although there are studies showing that mobile phone solutions can improve health service delivery outcomes in the developed world, there is little empirical evidence that demonstrates the impact of mHealth interventions on key maternal health outcomes in low income settings.A non-randomized controlled study was conducted in the Amhara region, Ethiopia in 10 health facilities (5 intervention, 5 control together serving around 250,000 people. Health workers in the intervention group received an android phone (3 phones per facility loaded with an application that sends reminders for scheduled visits during antenatal care (ANC, delivery and postnatal care (PNC, and educational messages on dangers signs and common complaints during pregnancy. The intervention was developed at Addis Ababa University in Ethiopia. Primary outcomes were the percentage of women who had at least 4 ANC visits, institutional delivery and PNC visits at the health center after 12 months of implementation of the intervention.Overall 933 and 1037 women were included in the cross-sectional surveys at baseline and at follow-up respectively. In addition, the medical records of 1224 women who had at least one antenatal care visit were followed in the longitudinal study. Women who had their ANC visit in the intervention health centers were significantly more likely to deliver their baby in the same health center compared to the control group (43.1% versus 28.4%; Adjusted Odds Ratio (AOR: 1.98 (95%CI 1.53-2.55. A significantly higher percentage of women who had ANC in the intervention group had PNC in the same health center compared to the control health centers (41.2% versus 21.1%: AOR: 2.77 (95%CI 2.12-3.61.Our findings demonstrated that a locally customized mHealth application during ANC can significantly improve delivery and postnatal care service utilization possibly through positively influencing the behavior of health workers and their clients.

  20. Assessing the risk of attack in the management of asthma: a review and proposal for revision of the current control-centred paradigm.

    Science.gov (United States)

    Blakey, John D; Woolnough, Kerry; Fellows, Jodie; Walker, Samantha; Thomas, Mike; Pavord, Ian D

    2013-09-01

    Asthma guidelines focus on day-to-day control of symptoms. However, asthma attacks remain common. They continue to cause mortality and considerable morbidity, and are a major financial burden to the UK National Health Service (NHS) and the wider community. Asthma attacks have chronic consequences, being associated with loss of lung function and significant psychological morbidity. In this article we argue that addressing daily symptom control is only one aspect of asthma treatment, and that there should be a more explicit focus on reducing the risk of asthma attacks. Management of future risk by general practitioners is already central to other conditions such as ischaemic heart disease and chronic renal impairment. We therefore propose a revised approach that separately considers the related domains of daily control and future risk of asthma attack. We believe this approach will have advantages over the current 'stepwise' approach to asthma management. It should encourage individualised treatment, including non-pharmacological measures, and thus may lead to more efficacious and less harmful management strategies. We speculate that this type of approach has the potential to reduce morbidity and healthcare costs related to asthma attacks.

  1. Oral paracetamol and/or ibuprofen for treating pain after soft tissue injuries: Single centre double-blind, randomised controlled clinical trial.

    Science.gov (United States)

    Hung, Kevin K C; Graham, Colin A; Lo, Ronson S L; Leung, Yuk Ki; Leung, Ling Yan; Man, S Y; Woo, W K; Cattermole, Giles N; Rainer, Timothy H

    2018-01-01

    Soft tissue injuries commonly present to the emergency department (ED), often with acute pain. They cause significant suffering and morbidity if not adequately treated. Paracetamol and ibuprofen are commonly used analgesics, but it remains unknown if either one or the combination of both is superior for pain control. To investigate the analgesic effect of paracetamol, ibuprofen and the combination of both in the treatment of soft tissue injury in an ED, and the side effect profile of these drugs. Double-blind, double dummy, placebo-controlled randomised controlled trial. 782 adult patients presenting with soft tissue injury without obvious fractures attending the ED of a university hospital in the New Territories of Hong Kong were recruited. Patients were randomised using a random number table into three parallel arms of paracetamol only, ibuprofen only and a combination of paracetamol and ibuprofen in a 1:1:1 ratio. The primary outcome measure was pain score at rest and on activity in the first 2 hours and first 3 days. Data was analysed on an intention to treat basis. There was no statistically significant difference in pain score in the initial two hours between the three groups, and no clinically significant difference in pain score in the first three days. There was no difference in analgesic effects or side effects observed using oral paracetamol, ibuprofen or a combination of both in patients with mild to moderate pain after soft tissue injuries attending the ED. The study is registered with ClinicalTrials.gov (no. NCT00528658).

  2. Real-time Identification and Control of Satellite Signal Impairments Solution and Application of the Stratonovich Equation Part 1. Theoretical Development

    Science.gov (United States)

    Manning, Robert M.

    2016-01-01

    As satellite communications systems become both more complex and reliant with respect to their operating environment, it has become imperative to be able to identify, during real-time operation, the onset of one or more impairments to the quality of overall communications system integrity. One of the most important aspects to monitor of a satellite link operating within the Earth's atmosphere is the signal fading due to the occurrence of rain and/or phase scintillations. This, of course, must be done in the presence of the associated measurement uncertainty or potentially faulty measurement equipment such as in the Advanced Communication Technology Satellite (ACTS) experiment. In the present work, an approach originally suggested in 1991, and apparently still considered iconoclastic, will be significantly developed and applied to the satellite communications link on which the deleterious composite signal fade is the result of one or many component fade mechanisms. Through the measurement (with the attendant uncertainty or 'error' in the measurement) of such a composite fading satellite signal, it is desired to extract the level of each of the individual fading mechanisms so they can be appropriately mitigated before they impact the overall performance of the communications network. Rather than employing simple-minded deterministic filtering to the real-time fading, the present approach is built around all the models and/or descriptions used to describe the individual fade components, including their dynamic evolution. The latter is usually given by a first-order Langevin equation. This circumstance allows the description of the associated temporal transition probability densities of each of the component processes. By using this description, along with the real-time measurements of the composite fade (along with the measurement errors), one can obtain statistical estimates of the levels of each of the component fading mechanisms as well as their predicted values

  3. KNMI Data Centre: Easy access for all

    Science.gov (United States)

    van de Vegte, John; Som de Cerff, Wim; Plieger, Maarten; de Vreede, Ernst; Sluiter, Raymond; Willem Noteboom, Jan; van der Neut, Ian; Verhoef, Hans; van Versendaal, Robert; van Binnendijk, Martin; Kalle, Henk; Knopper, Arthur; Spit, Jasper; Mastop, Joeri; Klos, Olaf; Calis, Gijs; Ha, Siu-Siu; van Moosel, Wim; Klein Ikkink, Henk-Jan; Tosun, Tuncay

    2013-04-01

    KNMI is the Dutch institute for weather, climate research and seismology. It disseminates weather information to the public at large, the government, aviation and the shipping industry in the interest of safety, the economy and a sustainable environment. To gain insight into long-term developments KNMI conducts research on climate change. Making the knowledge, data and information on hand at KNMI accessible is one core activity. A huge part of the KNMI information is from numerical models, insitu sensor networks and remote sensing satellites. This digital collection is mostly internal only available and is a collection of non searchable , non standardized file formats, lacking documentation and has no references to scientific publications. With the KNMI Data Centre (KDC) project these issues are tackled. In the project a user driven development approach with SCRUM was chosen to get maximum user involvement in a relative short development timeframe. Building on open standards and proven open source technology (which includes in-house developed software like ADAGUC WMS and Portal) resulted in a first release in December 2012 This presentation will focus on the aspects of KDC relating to its technical challenges, the development strategy and the initial usage results of the data centre.

  4. Satellite Communications Industry

    Science.gov (United States)

    1993-04-01

    Ariane $loom SAJAC 1 Hughes Satellite Japan 06/94 $150m SAJAC 2 Hughes Satellite Japan -- (spare) $150m SatcomHl GE GE Americom /95 $50m SOLIDARIDAD ...1 Hughes SCT (Mexico) 11/93 Ariane $loom SOLIDARIDAD 2 Hughes SCT (Mexico) /94 $loom Superbird Al Loral Space Com Gp (Jap) 11/92 Ariane $175m

  5. Partnership via Satellite.

    Science.gov (United States)

    Powell, Marie Clare

    1980-01-01

    Segments of the 1980 National Catholic Educational Association (NCEA) conference were to be telecast nationally by satellite. The author briefly explains the satellite transmission process and advises Catholic educators on how to pick up the broadcast through their local cable television system. (SJL)

  6. Satellite ATM Networks: Architectures and Guidelines Developed

    Science.gov (United States)

    vonDeak, Thomas C.; Yegendu, Ferit

    1999-01-01

    An important element of satellite-supported asynchronous transfer mode (ATM) networking will involve support for the routing and rerouting of active connections. Work published under the auspices of the Telecommunications Industry Association (http://www.tiaonline.org), describes basic architectures and routing protocol issues for satellite ATM (SATATM) networks. The architectures and issues identified will serve as a basis for further development of technical specifications for these SATATM networks. Three ATM network architectures for bent pipe satellites and three ATM network architectures for satellites with onboard ATM switches were developed. The architectures differ from one another in terms of required level of mobility, supported data rates, supported terrestrial interfaces, and onboard processing and switching requirements. The documentation addresses low-, middle-, and geosynchronous-Earth-orbit satellite configurations. The satellite environment may require real-time routing to support the mobility of end devices and nodes of the ATM network itself. This requires the network to be able to reroute active circuits in real time. In addition to supporting mobility, rerouting can also be used to (1) optimize network routing, (2) respond to changing quality-of-service requirements, and (3) provide a fault tolerance mechanism. Traffic management and control functions are necessary in ATM to ensure that the quality-of-service requirements associated with each connection are not violated and also to provide flow and congestion control functions. Functions related to traffic management were identified and described. Most of these traffic management functions will be supported by on-ground ATM switches, but in a hybrid terrestrial-satellite ATM network, some of the traffic management functions may have to be supported by the onboard satellite ATM switch. Future work is planned to examine the tradeoffs of placing traffic management functions onboard a satellite as

  7. Optimizing Data Centre Energy and Environmental Costs

    Science.gov (United States)

    Aikema, David Hendrik

    Data centres use an estimated 2% of US electrical power which accounts for much of their total cost of ownership. This consumption continues to grow, further straining power grids attempting to integrate more renewable energy. This dissertation focuses on assessing and reducing data centre environmental and financial costs. Emissions of projects undertaken to lower the data centre environmental footprints can be assessed and the emission reduction projects compared using an ISO-14064-2-compliant greenhouse gas reduction protocol outlined herein. I was closely involved with the development of the protocol. Full lifecycle analysis and verifying that projects exceed business-as-usual expectations are addressed, and a test project is described. Consuming power when it is low cost or when renewable energy is available can be used to reduce the financial and environmental costs of computing. Adaptation based on the power price showed 10--50% potential savings in typical cases, and local renewable energy use could be increased by 10--80%. Allowing a fraction of high-priority tasks to proceed unimpeded still allows significant savings. Power grid operators use mechanisms called ancillary services to address variation and system failures, paying organizations to alter power consumption on request. By bidding to offer these services, data centres may be able to lower their energy costs while reducing their environmental impact. If providing contingency reserves which require only infrequent action, savings of up to 12% were seen in simulations. Greater power cost savings are possible for those ceding more control to the power grid operator. Coordinating multiple data centres adds overhead, and altering at which data centre requests are processed based on changes in the financial or environmental costs of power is likely to increase this overhead. Tests of virtual machine migrations showed that in some cases there was no visible increase in power use while in others power use

  8. The satellite situation center

    International Nuclear Information System (INIS)

    Teague, M.J.; Sawyer, D.M.; Vette, J.I.

    1982-01-01

    Considerations related to the early planning for the International Magnetospheric Study (IMS) took into account the desirability of an establishment of specific entities for generating and disseminating coordination information for both retrospective and predictive periods. The organizations established include the IMS/Satellite Situation Center (IMS/SSC) operated by NASA. The activities of the SSC are related to the preparation of reports on predicted and actually achieved satellite positions, the response to inquiries, the compilation of information on satellite experiments, and the issue of periodic status summaries. Attention is given to high-altitude satellite services, other correlative satellite services, non-IMS activities of the SSC, a summary of the SSC request activity, and post-IMS and future activities

  9. Effectiveness and cost-effectiveness of body psychotherapy in the treatment of negative symptoms of schizophrenia – a multi-centre randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Priebe Stefan

    2013-01-01

    Full Text Available Abstract Background Negative symptoms of schizophrenia are frequently associated with poor long term outcomes. Established interventions have little, if any, positive effects on negative symptoms. Arts Therapies such as Body Psychotherapy (BPT have been suggested to reduce negative symptoms, but the existing evidence is limited. In a small exploratory trial a manualised form of group BPT led to significantly lower negative symptom levels both at the end of treatment and at 4 months follow-up as compared to supportive counseling. We designed a large multi-site trial to assess the effectiveness of a manualised BPT intervention in reducing negative symptoms, compared to an active control. Methods/Design In a randomised controlled trial, 256 schizophrenic outpatients with negative symptoms will be randomly allocated either to BPT or Pilates groups. In both conditions, patients will be offered two 90 minutes sessions per week in groups of about 8 patients over a period of 10 weeks. Outcomes are assessed at the end of treatment and at six months follow-up. The primary outcome is severity of negative symptoms, as measured by the Positive and Negative Symptom Scale (PANSS, whilst a range of secondary outcome measures include general psychopathology, social contacts, and quality of life. We will also assess the cost-effectiveness of the intervention. Discussion The study aims to evaluate the effectiveness of a promising form of group therapy which may help alleviate negative symptoms that are associated with unfavourable long-term outcomes and have so far been difficult to treat. If the trial is successful, it will add a new and effective option in the treatment of negative symptoms. Group BPT is manualised, might be attractive to many patients because of its unusual approach, and could potentially be rolled out to services at relatively little additional cost. Trial registration Current Controlled Trials ISRCTN84216587

  10. Oral paracetamol and/or ibuprofen for treating pain after soft tissue injuries: Single centre double-blind, randomised controlled clinical trial.

    Directory of Open Access Journals (Sweden)

    Kevin K C Hung

    Full Text Available Soft tissue injuries commonly present to the emergency department (ED, often with acute pain. They cause significant suffering and morbidity if not adequately treated. Paracetamol and ibuprofen are commonly used analgesics, but it remains unknown if either one or the combination of both is superior for pain control.To investigate the analgesic effect of paracetamol, ibuprofen and the combination of both in the treatment of soft tissue injury in an ED, and the side effect profile of these drugs.Double-blind, double dummy, placebo-controlled randomised controlled trial. 782 adult patients presenting with soft tissue injury without obvious fractures attending the ED of a university hospital in the New Territories of Hong Kong were recruited. Patients were randomised using a random number table into three parallel arms of paracetamol only, ibuprofen only and a combination of paracetamol and ibuprofen in a 1:1:1 ratio. The primary outcome measure was pain score at rest and on activity in the first 2 hours and first 3 days. Data was analysed on an intention to treat basis.There was no statistically significant difference in pain score in the initial two hours between the three groups, and no clinically significant difference in pain score in the first three days.There was no difference in analgesic effects or side effects observed using oral paracetamol, ibuprofen or a combination of both in patients with mild to moderate pain after soft tissue injuries attending the ED.The study is registered with ClinicalTrials.gov (no. NCT00528658.

  11. Surgical management and outcome of blunt major liver injuries: experience of damage control laparotomy with perihepatic packing in one trauma centre.

    Science.gov (United States)

    Lin, Being-Chuan; Fang, Jen-Feng; Chen, Ray-Jade; Wong, Yon-Cheong; Hsu, Yu-Pao

    2014-01-01

    This retrospective study aimed to assess the clinical experience and outcome of damage control laparotomy with perihepatic packing in the management of blunt major liver injuries. From January 1998 to December 2006, 58 patients of blunt major liver injury, American Association for the Surgery of Trauma-Organ Injury Scale (AAST-OIS) equal or greater than III, were operated with perihepatic packing at our institute. Demographic data, intra-operative findings, operative procedures, adjunctive managements and outcome were reviewed. To determine whether there was statistical difference between the survivor and non-survivor groups, data were compared by using Mann-Whitney U test for continuous variables, either Pearson's chi-square test or with Yates continuity correction for contingency tables, and results were considered statistically significant if phepatic artery ligation (n=11) and 7 patients required post-laparotomy hepatic transarterial embolization. Of the 58 patients, 28 survived and 30 died with a 52% mortality rate. Of the 30 deaths, uncontrolled liver bleeding in 24-h caused 25 deaths and delayed sepsis caused residual 5 deaths. The mortality rate versus OIS was grade III: 30% (6/20), grade IV: 54% (13/24), and grade V: 79% (11/14), respectively. On univariate analysis, the significant predictors of mortality were OIS grade (p=0.019), prolonged initial prothrombin time (PT) (p=0.004), active partial thromboplastin time (APTT) (p<0.0001) and decreased platelet count (p=0.005). The mortality rate of surgical blunt major liver injuries remains high even with perihepatic packing. Since prolonged initial PT, APTT and decreased platelet count were associated with high risk of mortality, we advocate combination of damage control resuscitation with damage control laparotomy in these major liver injuries. Copyright © 2013 Elsevier Ltd. All rights reserved.

  12. Call Centre- Computer Telephone Integration

    Directory of Open Access Journals (Sweden)

    Dražen Kovačević

    2012-10-01

    Full Text Available Call centre largely came into being as a result of consumerneeds converging with enabling technology- and by the companiesrecognising the revenue opportunities generated by meetingthose needs thereby increasing customer satisfaction. Regardlessof the specific application or activity of a Call centre, customersatisfaction with the interaction is critical to the revenuegenerated or protected by the Call centre. Physical(v, Call centreset up is a place that includes computer, telephone and supervisorstation. Call centre can be available 24 hours a day - whenthe customer wants to make a purchase, needs information, orsimply wishes to register a complaint.

  13. Drug treatment of bothersome lower urinary tract symptoms after ureteric JJ-stent insertion: A contemporary, comparative, prospective, randomised placebo-controlled study, single-centre experience.

    Science.gov (United States)

    Hekal, Ihab A

    2016-12-01

    To provide a guide for medication to alleviate bothersome lower urinary tract symptoms (LUTS) in patients after JJ ureteric stenting. Between June 2011 and June 2015, a prospective randomised placebo-controlled study was conducted on 200 consecutive cases of ureteric stones that required JJ stents. All patients had signed informed consent and JJ-stent placement confirmed by X-ray. The patients were randomised into five groups: A, solifenacin 5 mg; B, trospium chloride 20 mg; C, antispasmodic; and E, α-blocker; and a placebo group (D). A standard model was created to lessen patient selection bias. Eligible patients were enrolled and assessed for side-effects and bothersome LUTS using the validated Ureteric Stent Symptoms Questionnaire. Appropriate statistical analysis was carried out. In all, 150 male patients in the five groups were compared. LUTS were less in groups A and B ( P  JJ-stent insertion, anti-muscarinic medication, namely solifenacin 5 mg or trospium chloride 20 mg, was the best. The advantage of trospium over solifenacin is in the control of frequency rather than the other symptoms. Addition of an α-blocker (alfuzosin 10 mg) is valuable when nocturia is the predominant symptom.

  14. SDI satellite autonomy using AI and Ada

    Science.gov (United States)

    Fiala, Harvey E.

    1990-01-01

    The use of Artificial Intelligence (AI) and the programming language Ada to help a satellite recover from selected failures that could lead to mission failure are described. An unmanned satellite will have a separate AI subsystem running in parallel with the normal satellite subsystems. A satellite monitoring subsystem (SMS), under the control of a blackboard system, will continuously monitor selected satellite subsystems to become alert to any actual or potential problems. In the case of loss of communications with the earth or the home base, the satellite will go into a survival mode to reestablish communications with the earth. The use of an AI subsystem in this manner would have avoided the tragic loss of the two recent Soviet probes that were sent to investigate the planet Mars and its moons. The blackboard system works in conjunction with an SMS and a reconfiguration control subsystem (RCS). It can be shown to be an effective way for one central control subsystem to monitor and coordinate the activities and loads of many interacting subsystems that may or may not contain redundant and/or fault-tolerant elements. The blackboard system will be coded in Ada using tools such as the ABLE development system and the Ada Production system.

  15. Assessing the effectiveness of a patient-centred computer-based clinic intervention, Health-E You/Salud iTu, to reduce health disparities in unintended pregnancies among Hispanic adolescents: study protocol for a cluster randomised control trial.

    Science.gov (United States)

    Tebb, Kathleen P; Rodriguez, Felicia; Pollack, Lance M; Trieu, Sang Leng; Hwang, Loris; Puffer, Maryjane; Adams, Sally; Ozer, Elizabeth M; Brindis, Claire D

    2018-01-10

    Teen pregnancy rates in the USA remain higher than any other industrialised nation, and pregnancies among Hispanic adolescents are disproportionately high. Computer-based interventions represent a promising approach to address sexual health and contraceptive use disparities. Preliminary findings have demonstrated that the Health-E You/Salud iTu, computer application (app) is feasible to implement, acceptable to Latina adolescents and improves sexual health knowledge and interest in selecting an effective contraceptive method when used in conjunction with a healthcare visit. The app is now ready for efficacy testing. The purpose of this manuscript is to describe patient-centred approaches used both in developing and testing the Health-E You app and to present the research methods used to evaluate its effectiveness in improving intentions to use an effective method of contraception as well as actual contraceptive use. This study is designed to assess the effectiveness of a patient-centred computer-based clinic intervention, Health-E You/Salud  iTu, on its ability to reduce health disparities in unintended pregnancies among Latina adolescent girls. This study uses a cluster randomised control trial design in which 18 school-based health centers from the Los Angeles Unified School District were randomly assigned, at equal chance, to either the intervention ( Health-E You app) or control group. Analyses will examine differences between the control and intervention group's knowledge of and attitudes towards contraceptive use, receipt of contraception at the clinic visit and self-reported use of contraception at 3-month and 6-month follow-ups. The study began enrolling participants in August 2016, and a total of 1400 participants (700 per treatment group) are expected to be enrolled by March 2018. Ethics approval was obtained through the University of California, San Francisco Institutional Review Board. Results of this trial will be submitted for publication in peer

  16. SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment.

    Science.gov (United States)

    Montero-Odasso, Manuel; Almeida, Quincy J; Burhan, Amer M; Camicioli, Richard; Doyon, Julien; Fraser, Sarah; Li, Karen; Liu-Ambrose, Teresa; Middleton, Laura; Muir-Hunter, Susan; McIlroy, William; Morais, José A; Pieruccini-Faria, Frederico; Shoemaker, Kevin; Speechley, Mark; Vasudev, Akshya; Zou, G Y; Berryman, Nicolas; Lussier, Maxime; Vanderhaeghe, Leanne; Bherer, Louis

    2018-04-16

    Physical exercise, cognitive training, and vitamin D are low cost interventions that have the potential to enhance cognitive function and mobility in older adults, especially in pre-dementia states such as Mild Cognitive Impairment (MCI). Aerobic and progressive resistance exercises have benefits to cognitive performance, though evidence is somewhat inconsistent. We postulate that combined aerobic exercise (AE) and progressive resistance training (RT) (combined exercise) will have a better effect on cognition than a balance and toning control (BAT) intervention in older adults with MCI. We also expect that adding cognitive training and vitamin D supplementation to the combined exercise, as a multimodal intervention, will have synergistic efficacy. The SYNERGIC trial (SYNchronizing Exercises, Remedies in GaIt and Cognition) is a multi-site, double-blinded, five-arm, controlled trial that assesses the potential synergic effect of combined AE and RT on cognition and mobility, with and without cognitive training and vitamin D supplementation in older adults with MCI. Two-hundred participants with MCI aged 60 to 85 years old will be randomized to one of five arms, four of which include combined exercise plus combinations of dual-task cognitive training (real vs. sham) and vitamin D supplementation (3 × 10,000 IU/wk. vs. placebo) in a quasi-factorial design, and one arm which receives all control interventions. The primary outcome measure is the ADAS-Cog (13 and plus modalities) measured at baseline and at 6 months of follow-up. Secondary outcomes include neuroimaging, neuro-cognitive performance, gait and mobility performance, and serum biomarkers of inflammation (C reactive protein and interleukin 6), neuroplasticity (brain-derived neurotropic factor), endothelial markers (vascular endothelial growth factor 1), and vitamin D serum levels. The SYNERGIC Trial will establish the efficacy and feasibility of a multimodal intervention to improve cognitive performance

  17. For beginners in anaesthesia, self-training with an audiovisual checklist improves safety during anaesthesia induction: A prospective, randomised, controlled two-centre study.

    Science.gov (United States)

    Beck, Stefanie; Reich, Christian; Krause, Dorothea; Ruhnke, Bjarne; Daubmann, Anne; Weimann, Jörg; Zöllner, Christian; Kubitz, Jens

    2018-01-31

    Beginners in residency programmes in anaesthesia are challenged because working environment is complex, and they cannot rely on experience to meet challenges. During this early stage, residents need rules and structures to guide their actions and ensure patient safety. We investigated whether self-training with an electronic audiovisual checklist app on a mobile phone would produce a long-term improvement in the safety-relevant actions during induction of general anaesthesia. During the first month of their anaesthesia residency, we randomised 26 residents to the intervention and control groups. The study was performed between August 2013 and December 2014 in two university hospitals in Germany. In addition to normal training, the residents of the intervention group trained themselves on well tolerated induction using the electronic checklist for at least 60 consecutive general anaesthesia inductions. After an initial learning phase, all residents were observed during one induction of general anaesthesia. The primary outcome was the number of safety items completed during this anaesthesia induction. Secondary outcomes were similar observations 4 and 8 weeks later. Immediately, and 4 weeks after the first learning phase, residents in the intervention group completed a significantly greater number of safety checks than residents in the control group 2.8 [95% confidence interval (CI) 0.4 to 5.1, P = 0.021, Cohen's d = 0.47] and 3.7 (95% CI 1.3 to 6.1, P = 0.003, Cohen's d = 0.61), respectively. The difference between the groups had disappeared by 8 weeks: mean difference in the number of safety checks at 8 weeks was 0.4, 95% CI -2.0 to 2.8, P = 0.736, Cohen's d = 0.07). The use of an audiovisual self-training checklists improves safety-relevant behaviour in the early stages of a residency training programme in anaesthesia.

  18. Community resource centres to improve the health of women and children in Mumbai slums: study protocol for a cluster randomized controlled trial.

    Science.gov (United States)

    Shah More, Neena; Das, Sushmita; Bapat, Ujwala; Rajguru, Mahesh; Alcock, Glyn; Joshi, Wasundhara; Pantvaidya, Shanti; Osrin, David

    2013-05-08

    The trial addresses the general question of whether community resource centers run by a non-government organization improve the health of women and children in slums. The resource centers will be run by the Society for Nutrition, Education and Health Action, and the trial will evaluate their effects on a series of public health indicators. Each resource center will be located in a vulnerable Mumbai slum area and will serve as a base for salaried community workers, supervised by officers and coordinators, to organize the collection and dissemination of health information, provision of services, home visits to identify and counsel families at risk, referral of individuals and families to appropriate services and support for their access, meetings of community members and providers, and events and campaigns on health issues. A cluster randomized controlled trial in which 20 urban slum areas with resource centers are compared with 20 control areas. Each cluster will contain approximately 600 households and randomized allocation will be in three blocked phases, of 12, 12 and 16 clusters. Any resident of an intervention cluster will be able to participate in the intervention, but the resource centers will target women and children, particularly women of reproductive age and children under 5.The outcomes will be assessed through a household census after 2 years of resource center operations. The primary outcomes are unmet need for family planning in women aged 15 to 49 years, proportion of children under 5 years of age not fully immunized for their ages, and proportion of children under 5 years of age with weight for height less than 2 standard deviations below the median for age and sex. Secondary outcomes describe adolescent pregnancies, home deliveries, receipt of conditional cash transfers for institutional delivery, other childhood anthropometric indices, use of public sector health and nutrition services, indices of infant and young child feeding, and consultation

  19. Using mobile phone text messages to improve insulin injection technique and glycaemic control in patients with diabetes mellitus: a multi-centre study in Turkey.

    Science.gov (United States)

    Celik, Selda; Cosansu, Gulhan; Erdogan, Semra; Kahraman, Alev; Isik, Sengul; Bayrak, Gulay; Bektas, Belgin; Olgun, Nermin

    2015-06-01

    To improve the knowledge and skills of diabetic patients on insulin injections using mobile phone short message services and to evaluate the association of this intervention with metabolic outcomes. Mobile communication technologies are widely used in Turkey, which maintains a diabetic population of more than 6·5 million. However, there are a limited number of studies using mobile technologies in the challenging and complicated management of diabetes. A one group pretest-posttest design was used in this study. The study sample consisted of 221 people with type 1 and type 2 Diabetes Mellitus from eight outpatient clinics in six cities in Turkey. The 'Demographic and diabetes-related information Form' and 'Insulin Injection Technique and Knowledge Form' were used in the initial interview. Subsequently, 12 short messages related to insulin administration were sent to patients twice a week for six months. Each patient's level of knowledge and skills regarding both the insulin injection technique and glycaemic control (glycated haemoglobin A1c) levels were measured at three months and six months during the text messaging period and six months later (12 months total) when text messaging was stopped. The mean age of the patients with diabetes was 39·8 ± 16·2 years (min: 18; max: 75). More than half of the patients were females with a mean duration of diabetes of 11·01 ± 7·22 years (min 1; max: 32). Following the text message reminders, the patients' level of knowledge and skills regarding the insulin injection technique improved at month 3 and 6 (p 12 compared to the baseline values (p insulin injection sites and the frequency of rotation of skin sites for insulin injections also increased. This study demonstrated that a short message services-based information and reminder system on insulin injection administration provided to insulin-dependent patients with diabetes by nurses resulted in improved self-administration of insulin and metabolic control

  20. Life- and person-centred help in Mecklenburg-Western Pomerania, Germany (DelpHi: study protocol for a randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Thyrian Jochen

    2012-05-01

    Full Text Available Abstract Background The provision of appropriate medical and nursing care for people with dementia is a major challenge for the healthcare system in Germany. New models of healthcare provision need to be developed, tested and implemented on the population level. Trials in which collaborative care for dementia in the primary care setting were studied have demonstrated its effectiveness. These studies have been conducted in different healthcare systems, however, so it is unclear whether these results extend to the specific context of the German healthcare system. The objective of this population-based intervention trial in the primary care setting is to test the efficacy and efficiency of implementing a subsidiary support system on a population level for persons with dementia who live at home. Methods and study design The study was designed to assemble a general physician-based epidemiological cohort of people above the age of 70 who live at home (DelpHi cohort. These people are screened for eligibility to participate in a trial of dementia care management (DelpHi trial. The trial is a cluster-randomised, controlled intervention trial with two arms (intervention and control designed to test the efficacy and efficiency of implementing a subsidiary support system for persons with dementia who live at home. This subsidiary support system is initiated and coordinated by a dementia care manager: a nurse with dementia-specific qualifications who delivers the intervention according to a systematic, detailed protocol. The primary outcome is quality of life and healthcare for patients with dementia and their caregivers. This is a multidimensional outcome with a focus on four dimensions: (1 quality of life, (2 caregiver burden, (3 behavioural and psychological symptoms of dementia and (4 pharmacotherapy with an antidementia drug and prevention or suspension of potentially inappropriate medication. Secondary outcomes include the assessment of dementia

  1. Influence of inhomogeneous static magnetic field-exposure on patients with erosive gastritis: a randomized, self- and placebo-controlled, double-blind, single centre, pilot study.

    Science.gov (United States)

    Juhász, Márk; Nagy, Viktor L; Székely, Hajnal; Kocsis, Dorottya; Tulassay, Zsolt; László, János F

    2014-09-06

    This pilot study was devoted to the effect of static magnetic field (SMF)-exposure on erosive gastritis. The randomized, self- and placebo-controlled, double-blind, pilot study included 16 patients of the 2nd Department of Internal Medicine, Semmelweis University diagnosed with erosive gastritis. The instrumental analysis followed a qualitative (pre-intervention) assessment of the symptoms by the patient: lower heartburn (in the ventricle), upper heartburn (in the oesophagus), epigastric pain, regurgitation, bloating and dry cough. Medical diagnosis included a double-line upper panendoscopy followed by 30 min local inhomogeneous SMF-exposure intervention at the lower sternal region over the stomach with peak-to-peak magnetic induction of 3 mT and 30 mT m(-1) gradient at the target site. A qualitative (post-intervention) assessment of the same symptoms closed the examination. Sham- or SMF-exposure was used in a double-blind manner. The authors succeeded in justifying the clinically and statistically significant beneficial effect of the SMF- over sham-exposure on the symptoms of erosive gastritis, the average effect of inhibition was 56% by p = 0.001, n = 42 + 96. This pilot study was aimed to encourage gastroenterologists to test local, inhomogeneous SMF-exposure on erosive gastritis patients, so this intervention may become an evidence-based alternative or complementary method in the clinical use especially in cases when conventional therapy options are contraindicated. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  2. The Aube centre. 1997 statement

    International Nuclear Information System (INIS)

    1998-09-01

    Since January 1992 the Aube centre ensures the storage of 90% of the short life radioactive wastes produced in France. This educational booklet describes the organization of the activities in the centre from the storage of wastes to the radioactivity surveillance of the environment (air, surface and ground waters, river sediments, plants and milk). (J.S.)

  3. Proposal for an ecoradiological centre model

    International Nuclear Information System (INIS)

    Perovic, S.M.; Zunic, Z.; Demajo, M.; Konjevic, N.

    1998-01-01

    The problem of establishing an optimal Ecoradiological Centre Model is studied in some detail for the town of Kotor which is under the protection of the World Cultural and Natural Heritage. The proposed structure of the Centre is analyzed from the view of Engineering, Education and Scientific parameters. This Model is suitable for implementation as a network Centre Model for the state of Montenegro. Further, the modelling strategy of the ecoradiological condition control of natural, construction, bio and technological systems is elaborated. The proposal includes the ecoradiological monitoring, radioactive and electromagnetic radiation processing and protection for different natural zones as well as their different geostructures, aerial and hydrogeological conditions. The programme also includes all housing objects (hotels, flats, houses, office premises etc.). Here will also be presented the radiation protection and recommendations for the implementation of Title VII of the European Basic Safety Standards Directive (BSS), concerning significant increase in exposure due to natural radiation sources. Also, the proposal of Local Radiation Protection for the town of Kotor is presented. Our proposal for an Ecoradiological Centre Model presented here is in a form of a pilot programme, applicable also for other towns and states. (author)

  4. Tracking and data relay satellite system (TDRSS) capabilities

    Science.gov (United States)

    Spearing, R. E.

    1985-10-01

    The Tracking and Data Relay Satellite System (TDRSS) is the latest implementation to tracking and data acquisition network for near-earth orbiting satellite support designed to meet the requirements of the current and projected (to the year 2000) satellite user community. The TDRSS consists of a space segment (SS) and a ground segment (GS) that fit within NASA's Space Network (SN) complex controlled at the Goddard Space Flight Center. The SS currently employs a single satellite, TDRS-1, with two additional satellites to be deployed in January 1986 and July 1986. The GS contains the communications and equipment required to manage the three TDR satellites and to transmit and receive information to and from TDRSS user satellites. Diagrams and tables illustrating the TDRSS signal characteristics, the situation of TDRSS within the SN, the SN operations and element interrelationships, as well as future plans for new missions are included.

  5. Design of COSMIC: a randomized, multi-centre controlled trial comparing conservative or early surgical management of incomplete cervical cord syndrome without spinal instability.

    Science.gov (United States)

    Bartels, Ronald H M A; Hosman, Allard J F; van de Meent, Henk; Hofmeijer, Jeannette; Vos, Pieter E; Slooff, Willem Bart; Öner, F Cumhur; Coppes, Maarten H; Peul, Wilco C; Verbeek, André L M

    2013-01-31

    Incomplete cervical cord syndrome without spinal instability is a very devastating event for the patient and the family. It is estimated that up to 25% of all traumatic spinal cord lesions belong to this category. The treatment for this type of spinal cord lesion is still subject of discussion. From a biological point of view early surgery could prevent secondary damage due to ongoing compression of the already damaged spinal cord. Historically, however, conservative treatment was propagated with good clinical results. Proponents for early surgery as well those favoring conservative treatment are still in debate. The proposed trial will contribute to the discussion and hopefully also to a decrease in the variability of clinical practice. A randomized controlled trial is designed to compare the clinical outcome of early surgical strategy versus a conservative approach. The primary outcome is clinical outcome according to mJOA. This also measured by ASIA score, DASH score and SCIM III score. Other endpoints are duration of the stay at a high care department (medium care, intensive care), duration of the stay at the hospital, complication rate, mortality rate, sort of rehabilitation, and quality of life. A sample size of 36 patients per group was calculated to reach a power of 95%. The data will be analyzed as intention-to-treat at regular intervals, but the end evaluation will take place at two years post-injury. At the end of the study, clinical outcomes between treatments attitudes can be compared. Efficacy, but also efficiency can be determined. A goal of the study is to determine which treatment will result in the best quality of life for the patients. This study will certainly contribute to more uniformity of treatment offered to patients with a special sort of spinal cord injury. Gov: NCT01367405.

  6. Early home-based group education to support informed decision-making among patients with end-stage renal disease: a multi-centre randomized controlled trial.

    Science.gov (United States)

    Massey, Emma K; Gregoor, Peter J H Smak; Nette, Robert W; van den Dorpel, Marinus A; van Kooij, Anthony; Zietse, Robert; Zuidema, Willij C; Timman, Reinier; Busschbach, Jan J; Weimar, Willem

    2016-05-01

    The aim was to test the effectiveness of early home-based group education on knowledge and communication about renal replacement therapy (RRT). We conducted a randomized controlled trial using a cross-over design among 80 end-stage renal disease (ESRD) patients. Between T0 and T1 (weeks 1-4) Group 1 received the intervention and Group 2 received standard care. Between T1 and T2 (weeks 5-8) Group 1 received standard care and Group 2 received the intervention. The intervention was a group education session on RRT options held in the patient's home given by social workers. Patients invited members from their social network to attend. Self-report questionnaires were used at T0, T1 and T2 to measure patients' knowledge and communication, and concepts from the Theory of Planned Behaviour such as attitude. Comparable questionnaires were completed pre-post intervention by 229 attendees. Primary RRT was registered up to 2 years post-intervention. Multilevel linear modelling was used to analyse patient data and paired t-tests for attendee data. Statistically significant increases in the primary targets knowledge and communication were found among patients and attendees after receiving the intervention. The intervention also had a significant effect in increasing positive attitude toward living donation and haemodialysis. Of the 80 participants, 49 underwent RRT during follow-up. Of these, 34 underwent a living donor kidney transplant, of which 22 were pre-emptive. Early home-based group education supports informed decision-making regarding primary RRT for ESRD patients and their social networks and may remove barriers to pre-emptive transplantation. © The Author 2015. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

  7. Successfully reducing newborn asphyxia in the labour unit in a large academic medical centre: a quality improvement project using statistical process control.

    Science.gov (United States)

    Hollesen, Rikke von Benzon; Johansen, Rie Laurine Rosenthal; Rørbye, Christina; Munk, Louise; Barker, Pierre; Kjaerbye-Thygesen, Anette

    2018-02-03

    A safe delivery is part of a good start in life, and a continuous focus on preventing harm during delivery is crucial, even in settings with a good safety record. In January 2013, the labour unit at Copenhagen University Hospital, Hvidovre, undertook a quality improvement (QI) project to prevent asphyxia and reduced the percentage of newborns with asphyxia by 48%. The change theory consisted of two primary elements: (1) the clinical content, including three clinical bundles of evidence-based care, a 'delivery bundle', an 'oxytocin bundle' and a 'vacuum extraction bundle'; (2) an implementation theory, including improving skills in interpretation of cardiotocography, use of QI methods and participation in a national learning network. The Model for Improvement and Deming's system of profound knowledge were used as a methodological framework. Data on compliance with the care bundles and the number of deliveries between newborns with asphyxia (Apgar statistical process control. Compliance with all three clinical care bundles improved to 95% or more, and the percentages of newborns with pH <7 and Apgar <7 after 5 min were reduced by 48% and 31%, respectively. In general, the QI approach strengthened multidisciplinary teamwork, systematised workflow and structured communication around the deliveries. Changes included making a standard memo in the medical record, the use of a bedside whiteboard, bedside handovers, shared decisions with a peer when using an oxytocin infusion and the use of a checklist before vacuum extractions. This QI project illustrates how aspects of patient safety, such as the prevention of asphyxia, can be improved using QI methods to more reliably implement best practice, even in high-performing systems. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  8. The Head Injury Retrieval Trial (HIRT): a single-centre randomised controlled trial of physician prehospital management of severe blunt head injury compared with management by paramedics only.

    Science.gov (United States)

    Garner, Alan A; Mann, Kristy P; Fearnside, Michael; Poynter, Elwyn; Gebski, Val

    2015-11-01

    Advanced prehospital interventions for severe brain injury remains controversial. No previous randomised trial has been conducted to evaluate additional physician intervention compared with paramedic only care. Participants in this prospective, randomised controlled trial were adult patients with blunt trauma with either a scene GCS score definition), or GCSdefinition). Patients were randomised to either standard ground paramedic treatment or standard treatment plus a physician arriving by helicopter. Patients were evaluated by 30-day mortality and 6-month Glasgow Outcome Scale (GOS) scores. Due to high non-compliance rates, both intention-to-treat and as-treated analyses were preplanned. 375 patients met the original definition, of which 197 was allocated to physician care. Differences in the 6-month GOS scores were not significant on intention-to-treat analysis (OR 1.11, 95% CI 0.74 to 1.66, p=0.62) nor was the 30-day mortality (OR 0.91, 95% CI 0.60 to 1.38, p=0.66). As-treated analysis showed a 16% reduction in 30-day mortality in those receiving additional physician care; 60/195 (29%) versus 81/180 (45%), pdefinition, of which 182 were allocated to physician care. The 6-month GOS scores were not significantly different on intention-to-treat analysis (OR 1.14, 95% CI 0.73 to 1.75, p=0.56) nor was the 30-day mortality (OR 1.05, 95% CI 0.66 to 1.66, p=0.84). As-treated analyses were also not significantly different. This trial suggests a potential mortality reduction in patients with blunt trauma with GCSdefinition only). Confirmatory studies which also address non-compliance issues are needed. NCT00112398. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  9. Design of COSMIC: a randomized, multi-centre controlled trial comparing conservative or early surgical management of incomplete cervical cord syndrome without spinal instability

    Directory of Open Access Journals (Sweden)

    Bartels Ronald HMA

    2013-01-01

    Full Text Available Abstract Background Incomplete cervical cord syndrome without spinal instability is a very devastating event for the patient and the family. It is estimated that up to 25% of all traumatic spinal cord lesions belong to this category. The treatment for this type of spinal cord lesion is still subject of discussion. From a biological point of view early surgery could prevent secondary damage due to ongoing compression of the already damaged spinal cord. Historically, however, conservative treatment was propagated with good clinical results. Proponents for early surgery as well those favoring conservative treatment are still in debate. The proposed trial will contribute to the discussion and hopefully also to a decrease in the variability of clinical practice. Methods/Design A randomized controlled trial is designed to compare the clinical outcome of early surgical strategy versus a conservative approach. The primary outcome is clinical outcome according to mJOA. This also measured by ASIA score, DASH score and SCIM III score. Other endpoints are duration of the stay at a high care department (medium care, intensive care, duration of the stay at the hospital, complication rate, mortality rate, sort of rehabilitation, and quality of life. A sample size of 36 patients per group was calculated to reach a power of 95%. The data will be analyzed as intention-to-treat at regular intervals, but the end evaluation will take place at two years post-injury. Discussion At the end of the study, clinical outcomes between treatments attitudes can be compared. Efficacy, but also efficiency can be determined. A goal of the study is to determine which treatment will result in the best quality of life for the patients. This study will certainly contribute to more uniformity of treatment offered to patients with a special sort of spinal cord injury. Trial Registration Gov: NCT01367405

  10. Protected transitional solution to transformational satellite communications

    Science.gov (United States)

    Brand, Jerry C.

    2005-06-01

    As the Warfighter progresses into the next generation battlefield, transformational communications become evident as an enabling technology. Satellite communications become even more vital as the battles range over greater non-contiguous spaces. While current satellite communications provide suitable beyond line-of-sight communications and the Transformational Communications Architecture (TCA) sets the stage for sound information exchange, a realizable transition must occur to ensure successful succession to this higher level. This paper addresses the need for a planned escalation to the next generation satellite communications architecture and offers near-term alternatives. Commercial satellite systems continue to enable the Warfighter to reach back to needed information resources, providing a large majority of available bandwidth. Four areas of concentration for transition include encrypted Telemetry, Tracking and Control (or Command) (TT&C), encrypted and covered data, satellite attack detection and protection, and operational mobility. Solution methodologies include directly embedding COMSEC devices in the satellites and terminals, and supplementing existing terminals with suitable equipment and software. Future satellites planned for near-term launches can be adapted to include commercial grade and higher-level secure equipment. Alternately, the expected use of programmable modems (Software Defined Radios (SDR)) enables incorporation of powerful cipher methods approaching military standards as well as waveforms suitable for on-the-move operation. Minimal equipment and software additions on the satellites can provide reasonable attack detection and protection methods in concert with the planned satellite usage. Network management suite modifications enable cohesive incorporation of these protection schemes. Such transitional ideas offer a smooth and planned transition as the TCA takes life.

  11. Satellite Application for Disaster Management Information Systems

    Science.gov (United States)

    Okpanachi, George

    Abstract Satellites are becoming increasingly vital to modern day disaster management activities. Earth observation (EO) satellites provide images at various wavelengths that assist rapid-mapping in all phases of the disaster management cycle: mitigation of potential risks in a given area, preparedness for eventual disasters, immediate response to a disaster event, and the recovery/reconstruction efforts follo wing it. Global navigation satellite systems (GNSS) such as the Global Positioning System (GPS) assist all the phases by providing precise location and navigation data, helping manage land and infrastructures, and aiding rescue crews coordinate their search efforts. Effective disaster management is a complex problem, because it involves many parameters, which are usually not easy to measure and even identify: Analysis of current situation, planning, optimum resource management, coordination, controlling and monitoring current activities and making quick and correct decisions are only some of these parameters, whose complete list is very long. Disaster management information systems (DMIS) assist disaster management to analyse the situation better, make decisions and suggest further actions following the emergency plans. This requires not only fast and thorough processing and optimization abilities, but also real-time data provided to the DMIS. The need of DMIS for disaster’s real-time data can be satisfied by small satellites data utilization. Small satellites can provide up-to-data, plus a better media to transfer data. This paper suggests a rationale and a framework for utilization of small Satellite data by DMIS. DMIS should be used ‘’before’’, ‘’during’’ and ‘’after’’ the disasters. Data provided by the Small Satellites are almost crucial in any period of the disasters, because early warning can save lives, and satellite data may help to identify disasters before they occur. The paper also presents’ ‘when’’,

  12. Probability of satellite collision

    Science.gov (United States)

    Mccarter, J. W.

    1972-01-01

    A method is presented for computing the probability of a collision between a particular artificial earth satellite and any one of the total population of earth satellites. The collision hazard incurred by the proposed modular Space Station is assessed using the technique presented. The results of a parametric study to determine what type of satellite orbits produce the greatest contribution to the total collision probability are presented. Collision probability for the Space Station is given as a function of Space Station altitude and inclination. Collision probability was also parameterized over miss distance and mission duration.

  13. The Head Injury Retrieval Trial (HIRT): a single-centre randomised controlled trial of physician prehospital management of severe blunt head injury compared with management by paramedics only

    Science.gov (United States)

    Garner, Alan A; Mann, Kristy P; Fearnside, Michael; Poynter, Elwyn; Gebski, Val

    2015-01-01

    Background Advanced prehospital interventions for severe brain injury remains controversial. No previous randomised trial has been conducted to evaluate additional physician intervention compared with paramedic only care. Methods Participants in this prospective, randomised controlled trial were adult patients with blunt trauma with either a scene GCS score <9 (original definition), or GCS<13 and an Abbreviated Injury Scale score for the head region ≥3 (modified definition). Patients were randomised to either standard ground paramedic treatment or standard treatment plus a physician arriving by helicopter. Patients were evaluated by 30-day mortality and 6-month Glasgow Outcome Scale (GOS) scores. Due to high non-compliance rates, both intention-to-treat and as-treated analyses were preplanned. Results 375 patients met the original definition, of which 197 was allocated to physician care. Differences in the 6-month GOS scores were not significant on intention-to-treat analysis (OR 1.11, 95% CI 0.74 to 1.66, p=0.62) nor was the 30-day mortality (OR 0.91, 95% CI 0.60 to 1.38, p=0.66). As-treated analysis showed a 16% reduction in 30-day mortality in those receiving additional physician care; 60/195 (29%) versus 81/180 (45%), p<0.01, Number needed to treat =6. 338 patients met the modified definition, of which 182 were allocated to physician care. The 6-month GOS scores were not significantly different on intention-to-treat analysis (OR 1.14, 95% CI 0.73 to 1.75, p=0.56) nor was the 30-day mortality (OR 1.05, 95% CI 0.66 to 1.66, p=0.84). As-treated analyses were also not significantly different. Conclusions This trial suggests a potential mortality reduction in patients with blunt trauma with GCS<9 receiving additional physician care (original definition only). Confirmatory studies which also address non-compliance issues are needed. Trial registration number NCT00112398. PMID:25795741

  14. Program of rehabilitative exercise and education to avert vascular events after non-disabling stroke or transient ischemic attack (PREVENT Trial: a multi-centred, randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Thompson Kara

    2010-12-01

    Full Text Available Abstract Background Despite lack of outward signs, most individuals after non-disabling stroke (NDS and transient ischemic attack (TIA have significant cardiovascular and cerebrovascular disease and are at high risk of a major stroke, hospitalization for other vascular events, or death. Most have multiple modifiable risk factors (e.g., hypertension, physical inactivity, hyperlipidaemia, diabetes, tobacco consumption, psychological stress. In addition, accelerated rates of depression, cognitive decline, and poor quality of sleep have been reported following TIA, which correlate with poor functional outcomes and reduced quality of life. Thus, NSD and TIA are important warning signs that should not be overlooked. The challenge is not unlike that facing other 'silent' conditions - to identify a model of care that is effective in changing people's current behaviors in order to avert further morbidity. Methods/Design A single blind, randomized controlled trial will be conducted at two sites to compare the effectiveness of a program of rehabilitative exercise and education versus usual care in modifying vascular risk factors in adults after NDS/TIA. 250 adults within 90 days of being diagnosed with NDS/TIA will be randomly allocated to a 12-week program of exercise and education (PREVENT or to an outpatient clinic assessment and discussion of secondary prevention recommendations with return clinic visits as indicated (USUAL CARE. Primary outcome measures will include blood pressure, waist circumference, 12-hour fasting lipid profile, and 12-hour fasting glucose/hemoglobin A1c. Secondary measures will include exercise capacity, walking endurance, physical activity, cognitive function, depression, goal attainment and health-related quality of life. Outcome assessment will be conducted at baseline, post-intervention, and 6- and 12-month follow-ups. Direct health care costs incurred over one year by PREVENT versus USUAL CARE participants will also be

  15. Treatment with L-citrulline and metformin in Duchenne muscular dystrophy: study protocol for a single-centre, randomised, placebo-controlled trial.

    Science.gov (United States)

    Hafner, Patricia; Bonati, Ulrike; Rubino, Daniela; Gocheva, Vanya; Zumbrunn, Thomas; Gueven, Nuri; Fischer, Dirk

    2016-08-03

    Duchenne muscular dystrophy (DMD) is an X-linked recessive disease that affects 1 in 3500-6000 male births. Despite broad research aiming to improve muscle function as well as heart and brain function, sufficient therapeutic efficacy has not yet been achieved and current therapeutic management is still supportive. In a recent pilot trial, oral treatment with L-arginine and metformin showed consistent changes of muscular metabolism both in vitro and in vivo by raising NO levels and expression of mitochondrial proteins in the skeletal muscle tissue of patients with DMD. This randomised, double-blind, placebo-controlled trial aims to demonstrate the superiority of L-citrulline and metformin therapy over placebo in DMD patients with regard to the Motor Function Measure (MFM) D1 subscore (primary endpoint) as well as additional clinical and subclinical tests. A total of 40-50 ambulant patients with DMD will be recruited at the outpatient department of the University of Basel Children's Hospital (Switzerland), as well as from the DMD patient registries of Switzerland, Germany and Austria. Patients will be randomly allocated to one of the two arms of the study and will receive either a combination of L-citrulline and metformin or placebo for 26 weeks. Co-medication with glucocorticoids is allowed. The primary endpoint is the change of the MFM D1 subscore from baseline to week 26 under L-citrulline and metformin therapy. Secondary endpoints will include the motor function measure (MFM) and its items and subscores, the 6-minute walking test, timed function tests and quantitative muscle testing. Furthermore, quantitative muscle MRI assessment to evaluate the muscle fat fraction as well as safety and biomarker laboratory analyses from blood will be included. For comparison, muscle metabolism and mitochondrial function will be analysed in 10-20 healthy age-matched male children. The aim of this study is to test if a 6-month treatment of a combination of L-citrulline and

  16. RTEMS CENTRE- RTEMS Improvement

    Science.gov (United States)

    Silva, Helder; Constantino, Alexandre; Freitas, Daniel; Coutinho, Manuel; Faustino, Sergio; Sousa, Jose; Dias, Luis; Zulianello, Marco

    2010-08-01

    During the last two years, EDISOFT's RTEMS CENTRE team [1], jointly with the European Space Agency and with the support of the worldwide RTEMS community [2], have been developing an activity to facilitate the qualification of the real-time operating system RTEMS (Real-Time Operating System for Multiprocessor Systems). This paper intends to give a high level visibility of the progress and the results obtained in the RTEMS Improvement [3] activity. The primary objective [4] of the project is to improve the RTEMS product, its documentation and to facilitate the qualification of RTEMS for future space missions, taking into consideration the specific operational requirements. The sections below provide a brief overview of the RTEMS operating system and the activities performed in the RTEMS Improvement project, which includes the selection of API managers to be qualified, the tailoring process, the requirements analysis, the reverse engineering and design of the RTEMS, the quality assurance process, the ISVV activities, the test campaign, the results obtained, the criticality analysis and the facilitation of qualification process.

  17. Thailand's nuclear research centre

    International Nuclear Information System (INIS)

    Yamkate, P.

    2001-01-01

    The Office of Atomic Energy for Peace, Thailand, is charged with three main tasks, namely, Nuclear Energy development Plan, Utilization of Nuclear Based technology Plan and Science and Technology Plan. Its activities are centred around the research reactor TRR-1/M1. The main areas of contribution include improvement in agricultural production, nuclear medicine and nuclear oncology, health care and nutrition, increasing industrial productivity and efficiency and, development of cadre competent in nuclear science and technology. The office also has the responsibility of ensuring nuclear safety, radiation safety and nuclear waste management. The office has started a new project in 1997 under which a 10 MWt research reactor, an isotope production facility and a waste processing and storage facility would be set up by General Atomic of USA. OAEP has a strong linkage with the IAEA and has been an active participant in RCA programmes. In the future OAEP will enhance its present capabilities in the use of radioisotopes and radiation and look into the possibility of using nuclear energy as an alternative energy resource. (author)

  18. The Adult Education Centre

    Directory of Open Access Journals (Sweden)

    Olga Drofenik

    1997-01-01

    Full Text Available The Adult Education Centre has drafted the professional foundations for the Master Plan for Adult Education which, according to the provisions stipulated in the Adult Education Act, will be adopted by the Parliament. The Master Plan specifies the goals, priority target groups, priority areas and a draft financial projection. The professional foundations include the ratings of adult education in studies about adult education trends in Slovenia and abroad. The paper presents research results relevant to the Master Plan and documents issued by international organizations, including research into the Decisive Global Factors of EC Development after 1992, the Report of Ministers of the OECD, and the Economic Development Strategy of Slovenia . All the above-mentioned documents emphasize the importance of life­long learning in achieving a more fulfilling personal life, faster economic growth and maintenance of social ties. In principle, the same views are shared in Slovenia. However, in practice the "multi-dimensional" nature of adult education often gives way to "education for production". This is why we especially stress the importance of adult education in the social and cultural context.

  19. 1 April 2011 - Croatian Rudjer Boskovic Institute (RBI)Director-General D. Ramljak visiting CMS Control Centre in Meyrin with Collaboration Spokesperson G. Tonelli; signing the guest book with Head of International Relations F. Pauss and visiting LHC superconducting magnet test hall with L. Walckiers.

    CERN Multimedia

    Maximilien brice

    2011-01-01

    1 April 2011 - Croatian Rudjer Boskovic Institute (RBI)Director-General D. Ramljak visiting CMS Control Centre in Meyrin with Collaboration Spokesperson G. Tonelli; signing the guest book with Head of International Relations F. Pauss and visiting LHC superconducting magnet test hall with L. Walckiers.

  20. 18 January 2011 - The British Royal Academy of Engineering in the LHC tunnel with CMS Collaboration Spokesperson G. Tonelli and Beams Department Head P. Collier; in the CERN Control Centre with P. Collier and LHC superconducting magnet test hall with Technology Department Head F. Bordry.

    CERN Multimedia

    Jean-Claude Gadmer

    2011-01-01

    18 January 2011 - The British Royal Academy of Engineering in the LHC tunnel with CMS Collaboration Spokesperson G. Tonelli and Beams Department Head P. Collier; in the CERN Control Centre with P. Collier and LHC superconducting magnet test hall with Technology Department Head F. Bordry.