DIGITAL PRESERVATION OF THE QUON SANG LUNG LAUNDRY BUILDING, FORT MACLEOD, ALBERTA

Directory of Open Access Journals (Sweden)

P. Dawson

2017-08-01

Full Text Available This paper describes the results of an emergency recording and archiving of a historic structure in Southern Alberta and explores the lessons learned. Digital recording of the Quon Sang Lung Laundry building in Fort Macleod, Alberta, was a joint initiative between Alberta Culture and Tourism and the University of Calgary. The Quon Sang Lung Laundry was a boomtown-style wood structure situated in the Fort Macleod Provincial Historic Area, Alberta. Built in the mid-1800s, the structure was one of the four buildings comprising Fort Macleod’s Chinatown. Its association with Chinese immigration, settlement, and emergence of Chinese-owned businesses in early twentieth-century Alberta, made the Quon Sang Lung Laundry a unique and very significant historic resource. In recent years, a condition assessment of the structure indicated that the building was not safe and that the extent of the instability could lead to a sudden collapse. In response, Alberta Culture and Tourism engaged the Departments of Anthropology and Archaeology and Geomatics Engineering from the University of Calgary, to digitally preserve the laundry building. A complete survey including the laser scanning of all the remaining elements of the original structure, was undertaken. Through digital modeling, the work guarantees that a three-dimensional representation of the building is available for future use. This includes accurate 3D renders of the exterior and interior spaces and a collection of architectural drawings comprising floor plans, sections, and elevations.

Digital Preservation of the Quon Sang Lung Laundry Building, Fort Macleod, Alberta

Science.gov (United States)

Dawson, P.; Baradaran, F.; Jahraus, A.; Rubalcava, E.; Farrokhi, A.; Robinson, C.

2017-08-01

This paper describes the results of an emergency recording and archiving of a historic structure in Southern Alberta and explores the lessons learned. Digital recording of the Quon Sang Lung Laundry building in Fort Macleod, Alberta, was a joint initiative between Alberta Culture and Tourism and the University of Calgary. The Quon Sang Lung Laundry was a boomtown-style wood structure situated in the Fort Macleod Provincial Historic Area, Alberta. Built in the mid-1800s, the structure was one of the four buildings comprising Fort Macleod's Chinatown. Its association with Chinese immigration, settlement, and emergence of Chinese-owned businesses in early twentieth-century Alberta, made the Quon Sang Lung Laundry a unique and very significant historic resource. In recent years, a condition assessment of the structure indicated that the building was not safe and that the extent of the instability could lead to a sudden collapse. In response, Alberta Culture and Tourism engaged the Departments of Anthropology and Archaeology and Geomatics Engineering from the University of Calgary, to digitally preserve the laundry building. A complete survey including the laser scanning of all the remaining elements of the original structure, was undertaken. Through digital modeling, the work guarantees that a three-dimensional representation of the building is available for future use. This includes accurate 3D renders of the exterior and interior spaces and a collection of architectural drawings comprising floor plans, sections, and elevations.

Narasi Cahaya Kearifan Lokal Dalam Film Sang Pencerah Karya Hanung Bramantyo

Directory of Open Access Journals (Sweden)

Dyah Gayatri Puspitasari

2017-01-01

ABSTRAK   Narasi merupakan unsur penting dalam film. Urutannya mengandung logika tertentu yang berkaitan dengan makna cerita film. Film dapat dikatakan sebagai narasi yang merep- resentasikan realitas. Namun karena film merupakan gubahan sutradara, maka urutan peris- tiwa itu tentunya sudah dibubuhi pesan atau niatan tertentu sutradara. Dengan mengambil film Sang Pencerah karya Hanung Bramantyo sebagai studi kasus, dilakukan identifikasi pesan dan makna yang termuat di dalam film tersebut. Kajian ini menggunakan metode analisis teks visual naratif dengan teori narasi Genette dan semiotika Peirce sebagai pembantu. Dari hasil analisis struktur narasiditemukan bahwa Sang Pencerah merupakan film alur tiga babak dengan pola linier. Aspek cahaya yang dikorelasikan dengan makna pencerahan, tampak dimanfaat- kan sebagai pengikat rangkaian inti cerita. Melalui analisis berbagai penanda visual selanjutnya ditemukan bahwa gagasan pembaharuan (pencerahan yang diketengahkan sutradara dalam film ini merupakanrasionalitas modernisme Barat versus Ahmad Dahlan. Sebuah rasionalitas yang mengejawantahkan kesantunan dan kearifan lokal sebagai keutuhan jati diri pengimbang kebaharuan.   Kata kunci: narasi, film, cahaya, pesan, modernisme

Characterization of Phenolic Compounds in Wine Lees

Directory of Open Access Journals (Sweden)

Ye Zhijing

2018-03-01

Full Text Available The effect of vinification techniques on phenolic compounds and antioxidant activity of wine lees are poorly understood. The present study investigated the antioxidant activity of white and red wine lees generated at early fermentation and during aging. In this study, the total phenol content (TPC, total tannin content (TTC, mean degree of polymerization (mDP, and antioxidant activities of five white and eight red wine lees samples from different vinification backgrounds were determined. The results showed that vinification techniques had a significant (p < 0.05 impact on total phenol and tannin content of the samples. White wine lees had high mDP content compared with red ones. Catechin (50–62% and epicatechin contents were the predominant terminal units of polymeric proanthocyanidin extracted from examined samples. Epigallocatechin was the predominant extension unit of white wine lees, whereas epicatechin was the predominant compound in red wine marc. The ORAC (oxygen radical absorbance capacity assay was strongly correlated with the DPPH (α, α-diphenyl-β-picrylhydrazyl assay, and the results showed the strong antioxidant activities associated with red wine lees (PN > 35 mg Trolox/g FDM (PN: Pinot noir lees; FDM: Freeze-dried Material. This study indicates that tannin is one of the major phenolic compounds available in wine lees that can be useful in human and animal health applications.

Analysis of 30 genes (355 SNPS) related to energy homeostasis for association with adiposity in European-American and Yup'ik Eskimo populations.

Science.gov (United States)

Chung, Wendy K; Patki, Amit; Matsuoka, Naoki; Boyer, Bert B; Liu, Nianjun; Musani, Solomon K; Goropashnaya, Anna V; Tan, Perciliz L; Katsanis, Nicholas; Johnson, Stephen B; Gregersen, Peter K; Allison, David B; Leibel, Rudolph L; Tiwari, Hemant K

2009-01-01

Human adiposity is highly heritable, but few of the genes that predispose to obesity in most humans are known. We tested candidate genes in pathways related to food intake and energy expenditure for association with measures of adiposity. We studied 355 genetic variants in 30 candidate genes in 7 molecular pathways related to obesity in two groups of adult subjects: 1,982 unrelated European Americans living in the New York metropolitan area drawn from the extremes of their body mass index (BMI) distribution and 593 related Yup'ik Eskimos living in rural Alaska characterized for BMI, body composition, waist circumference, and skin fold thicknesses. Data were analyzed by using a mixed model in conjunction with a false discovery rate (FDR) procedure to correct for multiple testing. After correcting for multiple testing, two single nucleotide polymorphisms (SNPs) in Ghrelin (GHRL) (rs35682 and rs35683) were associated with BMI in the New York European Americans. This association was not replicated in the Yup'ik participants. There was no evidence for gene x gene interactions among genes within the same molecular pathway after adjusting for multiple testing via FDR control procedure. Genetic variation in GHRL may have a modest impact on BMI in European Americans.

Enculturation, perceived stress, and physical activity: implications for metabolic risk among the Yup'ik--the Center for Alaska Native Health Research Study.

Science.gov (United States)

Bersamin, Andrea; Wolsko, Christopher; Luick, Bret R; Boyer, Bert B; Lardon, Cecile; Hopkins, Scarlett E; Stern, Judith S; Zidenberg-Cherr, Sheri

2014-06-01

American Indians and Alaska Natives (ANs) report among the lowest levels of physical activity in the USA, but there is very little systematic research examining the determinants of physical activity patterns in these populations. This study investigated the relationships between enculturation (or cultural traditionality), psychosocial stress, and physical activity in a community-based sample of Yup'ik women and men living in rural AN communities. Associations between these variables and several metabolic risk factors were also examined. A sample of 488 Yup'ik participants (284 women and 204 men) from six villages in the Yukon-Kuskokwim Delta region completed a wellness survey and an array of physiological assessments [e.g., body mass index (BMI), blood pressure]. A subset of 179 participants also completed a 3-day pedometer assessment of physical activity. Multivariate linear regression models indicated that participants who were more enculturated (i.e., living more of a traditional lifestyle) and who experienced lower levels of psychosocial stress were significantly more physically active. In turn, both lower levels of psychosocial stress and higher levels of physical activity were associated with lower BMI, lower percent body fat, and lower waist circumference. Findings underscore the importance of gaining a culturally specific understanding of physical activity patterns in indigenous groups in order to inform effective health promotion strategies.

Effect of Herbal Acupuncture with Sang-hwang(Phellinus linteus on High Fat Diet-induced Obesity in Rats

Directory of Open Access Journals (Sweden)

Ji Hyun Kim

2004-02-01

Full Text Available Acupuncture has fairly good weight-reducing effect in treating simple obesity due to the neuroendocrine regulation. In this study, the anti-obesity effects of herbal acupuncture (HA with Sang-hwang (Phellinus linteus at Fuai (SP16 were investigated in the rat fed on high-fat (HF diet. Sang-hwang mushroom has been proven to have anti-carcinogenic effects and Sang-hwang extracts are highly effective in treatment and preventive treatment of AIDS, diabetes and high blood-pressure. To determine whether the Sang-hwang herbal acupuncture may have the anti-obesity effect, male Sprague-Dawley (4-wk-old rats were fed a HF diet for 5 wk, which produced significant weight gain compared to rats were fed a normal diet, and then herbal acupuncture were treated for 3 wk in HF diet group. The body weight, food consumption, food effeciency ratio (FER, body fat mass, plasma nitric oxide (NO were investigated in rats fed on normal diet, HF diet, and HF diet with HA (HF-diet-HA groups. NO has been proposed to be involved in the regulation of food intake. In addition, the expression of appetite peptides such as orexigenic peptide neuropeptide Y (NPY and the anorectic peptide cholecystokinin (CCK were observed in the hypothalamus. HF-HA group reduced body weight gain, FER, body fat contents and NO concentration compared to HF diet group. The expression of NPY was reduced in arcuate nucleus (ARC, and CCK was increased in the paraventricular nucleus (PVN after treatment of HA. In conclusion, Sang-hwang HA reduced adipocity, plasma NO and hypothalamic NPY, but increased CCK expression in the HF diet-induced obesity rat, therefore HA may have anti-obesity action through regulating body weight and appetite peptide of the central nervous system.

Blood group genotyping Genotipagem de grupos sangüíneos

Directory of Open Access Journals (Sweden)

Lilian Castilho

2004-01-01

Full Text Available Accurate phenotyping of red blood cells (RBCs can be difficult in transfusion-dependent patients such as those with thalassemia and sickle cells anemia because of the presence of previously transfused RBCs in the patient's circulation. Recently, the molecular basis associated with the expression of many blood group antigens was established. This allowed the development of a plethora of polymerase chain reaction-based tests for identification of the blood group antigens by testing DNA. The determination of blood group polymorphism at the genomic level facilitates the resolution of clinical problems that cannot be addressed by hemagglutination. They are useful to (a determine antigen types for which currently available antibodies are weakly reactive; (b type patients who have been recently transfused; (c identify fetuses at risk for hemolytic disease of the newborn; and (d to increase the reliability of repositories of antigen negative RBCs for transfusion. It is important to note that PCR based assays are prone to different types of errors that those observed with hemagglutination assays. For instance, contamination with amplified products may lead to false positive test results. In addition, the identification of a particular genotype does not necessarily mean that the antigen will be expressed on the RBC membrane.Os antígenos eritrocitários são herdados geneticamente e definidos por seqüências de aminoácidos específicos constituindo uma proteína ou por carboidratos ligados a estas proteínas ou à lipídios. A diversidade dos antígenos de grupos sangüíneos, como para qualquer outro traço biológico, encontra-se ao nível do gene. Existem atualmente mais de 250 antígenos eritrocitários que se encontram distribuídos em 29 sistemas de grupos sangüíneos, de acordo com a Nomenclatura da Sociedade Internacional de Transfusão Sangüínea (ISBT. Os genes que codificam 28 dos 29 sistemas de grupos sangüíneos já foram clonados e seq

Sulfuric acid dissolution of the Chashma-Sang deposit's green clays

International Nuclear Information System (INIS)

Mirzoev, D.Kh.; Boboev, Kh.E.; Pulatov, M.S.; Mirsaidov, U.M.

2005-01-01

Present article is presenting the results of the roentgen phase, thermodynamic and physical-chemical investigations of the green clays of the Chashma-Sang deposit of the Republic of Tajikistan. It is presented mineralogical and chemical composition of the mineral raw materials. Kinetic of decomposition of the oxides of aluminum and iron on temperature, time and concentration of the sulfuric acid has been investigated

On the linear programming bound for linear Lee codes.

Science.gov (United States)

Astola, Helena; Tabus, Ioan

2016-01-01

Based on an invariance-type property of the Lee-compositions of a linear Lee code, additional equality constraints can be introduced to the linear programming problem of linear Lee codes. In this paper, we formulate this property in terms of an action of the multiplicative group of the field [Formula: see text] on the set of Lee-compositions. We show some useful properties of certain sums of Lee-numbers, which are the eigenvalues of the Lee association scheme, appearing in the linear programming problem of linear Lee codes. Using the additional equality constraints, we formulate the linear programming problem of linear Lee codes in a very compact form, leading to a fast execution, which allows to efficiently compute the bounds for large parameter values of the linear codes.

Genetics, Diet, and Season Are Associated with Serum 25-Hydroxycholecalciferol Concentration in a Yup'ik Study Population from Southwestern Alaska.

Science.gov (United States)

Fohner, Alison E; Wang, Zhican; Yracheta, Joseph; O'Brien, Diane M; Hopkins, Scarlett E; Black, Jynene; Philip, Jacques; Wiener, Howard W; Tiwari, Hemant K; Stapleton, Patricia L; Tsai, Jesse M; Thornton, Timothy A; Boyer, Bert B; Thummel, Kenneth E

2016-02-01

Low blood vitamin D concentration is a concern for people living in circumpolar regions, where sunlight is insufficient for vitamin D synthesis in winter months and the consumption of traditional dietary sources of vitamin D is decreasing. The objective was to characterize the effects of diet, genetic variation, and season on serum 25-hydroxycholecalciferol [25(OH)D3] concentrations in Yup'ik Alaska Native people living in rural southwest Alaska. This study was a cross-sectional design that assessed the associations of traditional diet (via a biomarker, the RBC δ(15)N value), age, gender, body mass index (BMI), community location, and genotype of select single nucleotide polymorphisms (SNPs) in cytochrome P450 family 2, subfamily R, peptide 1 (CYP2R1), 7-dehydrocholesterol reductase (DHCR7), and vitamin D binding protein (GC) with serum 25(OH)D3 concentrations in 743 Yup'ik male and female participants, aged 14-93 y, recruited between September 2009 and December 2013. Yup'ik participants, on average, had adequate concentrations of serum 25(OH)D3 (31.1 ± 1.0 ng/mL). Variations in diet, BMI, age, gender, season of sample collection, and inland or coastal community geography were all significantly associated with serum 25(OH)D3 concentration. In models not adjusting for other covariates, age, diet, and seasonal effects explained 33.7%, 20.7%, and 9.8%, respectively, of variability in serum 25(OH)D3 concentrations. Of the 8 SNPs interrogated in CYP2R1 and DHCR7, only rs11023374 in CYP2R1 was significantly associated with serum 25(OH)D3, explaining 1.5% of variability. The GC haplotype explained an additional 2.8% of variability. Together, age, diet, gender, season of sample collection, BMI, geography of the community, and genotype at rs11023374 explained 52.5% of the variability in serum 25(OH)D3 concentrations. Lower consumption of the traditional diet was associated with lower serum concentrations of 25(OH)D3. Younger adults and youth in this community may be at

Tim Berners-Lee during the WSIS

CERN Multimedia

Maximilien Brice

2003-01-01

Tim Berners-Lee stands in front of the first web server at the Geneva Palexpo during the World Summit on the Information Society (WSIS) in 2003. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

76 FR 30947 - Stephen Lee Seldon: Debarment Order

Science.gov (United States)

2011-05-27

...] Stephen Lee Seldon: Debarment Order AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY... Act (the FD&C Act) permanently debarring Stephen Lee Seldon, M.D. from providing services in any... authority delegated to the Director (Staff Manual Guide 1410.35), finds that Stephen Lee Seldon has been...

Controverses institutionnelles et sociales autour du sang placentaire recueilli à des fins thérapeutiques1

OpenAIRE

Boileau, Claire

2003-01-01

Dans cet article, nous proposons d’exposer les résultats d’une recherche en anthropologie sociale et culturelle portant sur les enjeux du prélèvement de sang placentaire. Ce sang, riche en cellules souches, est prélevé au moment de l’accouchement sur des femmes ayant consenti au don. Il est ensuite traité puis stocké en attendant d’être greffé à des patients leucémiques. Appelé à se développer dans les années à venir, le prélèvement de cellules souches rencontre des difficultés de recueil non...

Interactions between yeast lees and wine polyphenols during simulation of wine aging. II. Analysis of desorbed polyphenol compounds from yeast lees.

Science.gov (United States)

Mazauric, Jean-Paul; Salmon, Jean-Michel

2006-05-31

In the first part of this work, the analysis of the polyphenolic compounds remaining in the wine after different contact times with yeast lees during simulation of red wine aging was undertaken. To achieve a more precise view of the wine polyphenols adsorbed on lees during red wine aging and to establish a clear balance between adsorbed and remnant polyphenol compounds, the specific analysis of the chemical composition of the adsorbed polyphenolic compounds (condensed tannins and anthocyanins) after their partial desorbtion from yeast lees by denaturation treatments was realized in the second part of the study. The total recovery of polyphenol compounds from yeast lees was not complete, since a rather important part of the initial wine colored polyphenols, especially those with a dominant blue color component, remained strongly adsorbed on yeast lees, as monitored by color tristimulus and reflectance spectra measurements. All anthocyanins were recovered at a rather high percentage (about 62%), and it was demonstrated that they were not adsorbed in relation with their sole polarity. Very few monomeric phenolic compounds were extracted from yeast lees. With the use of drastic denaturing treatments, the total recovery of condensed tannins reached 83%. Such tannins extracted from yeast lees exhibited very high polymeric size and a rather high percentage of galloylated residues by comparison with initial wine tannins, indicating that nonpolar tannins were preferentially desorbed from yeast lees by the extraction treatments.

Higher-derivative Lee-Wick unification

International Nuclear Information System (INIS)

Carone, Christopher D.

2009-01-01

We consider gauge coupling unification in Lee-Wick extensions of the Standard Model that include higher-derivative quadratic terms beyond the minimally required set. We determine how the beta functions are modified when some Standard Model particles have two Lee-Wick partners. We show that gauge coupling unification can be achieved in such models without requiring the introduction of additional fields in the higher-derivative theory and we comment on possible ultraviolet completions.

Constraints on the Lee-Wick Higgs sector

International Nuclear Information System (INIS)

Carone, Christopher D.; Primulando, Reinard

2009-01-01

Lee-Wick partners to the standard model Higgs doublet may appear at a mass scale that is significantly lower than that of the remaining Lee-Wick partner states. The relevant effective theory is a two-Higgs doublet model in which one doublet has wrong-sign kinetic and mass terms. We determine bounds on this effective theory, including those from neutral B-meson mixing, b→X s γ, and Z→bb. The results differ from those of conventional two-Higgs doublet models and lead to meaningful constraints on the Lee-Wick Higgs sector.

The Earl Lee Street Art Campaign

Science.gov (United States)

Bubba

2013-01-01

This article describes a catchy phrase with more to its meaning than first view. A slogan "All the girls love Earl Lee," appears in street art around the world. Earl Lee is a lovable, handsome man who owns the fictitious Earl Lube industries. Originally intended to bring a smile to people's faces at a time when there wasn't much to smile…

Tim Berners-Lee receives the Millennium Technology Prize

CERN Multimedia

2004-01-01

On 15 April, for his invention of the Web, Tim Berners-Lee was awarded the first ever Millennium Technology Prize by the Finnish Technology Award Foundation, which recognises technological innovations of lasting benefit to society. "Tim Berners-Lee's invention perfectly encapsulates the spirit of the Prize. The Web is encouraging new types of social networks, contributing to transparency and democracy, and opening up new avenues for information management and business development," underlined Pekka Tarjanne, chairman of the jury and former Secretary-General of the International Telecommunication Union (ITU). Tim Berners-Lee is congratulated by Jukka Valtasaari, Finland's Ambassador to the United States. Tim Berners-Lee created the first server, browser and editor, the HTML code, the URL address and the HTTP transmission protocol at CERN in 1990. CERN released the Web into the public domain in 1993. Tim Berners-Lee is currently head of the World Wide Web Consortium, managed by ERCIM (Europe...

Radiation bounce from the Lee-Wick construction?

International Nuclear Information System (INIS)

Karouby, Johanna; Brandenberger, Robert

2010-01-01

It was recently realized that matter modeled by the scalar field sector of the Lee-Wick standard model yields, in the context of a homogeneous and isotropic cosmological background, a bouncing cosmology. However, bouncing cosmologies induced by pressureless matter are in general unstable to the addition of relativistic matter (i.e. radiation). Here we study the possibility of obtaining a bouncing cosmology if we add not only radiation, but also its Lee-Wick partner, to the matter sector. We find that, in general, no bounce occurs. The only way to obtain a bounce is to choose initial conditions with very special phases of the radiation field and its Lee-Wick partner.

Web Inventor Berners-Lee starts a Blog

CERN Multimedia

Olson, Parmy

2005-01-01

Berners-Lee created what is known today as the World Wide Web. Now, just in time for the Web's 15th anniversary and after taking his proverbial stroll around the global dwelling of cyberspace, Berners-Lee is chatting with the rest of us about what he thinks with a blog

Complete synchronization of two Chen-Lee systems

International Nuclear Information System (INIS)

Sheu, L-J; Chen, J-H; Chen, H-K; Tam, L-M; Lao, S-K; Chen, W-C; Lin, K-T

2008-01-01

This study demonstrates that complete synchronization of two Chen-Lee chaotic systems can be easily achieved. The upper bound of the Chen-Lee chaotic system is estimated numerically. A controller is designed to synchronize two chaotic systems. Sufficient conditions for synchronization are obtained using Lyapunov's direct method. Two numerical examples are presented to verify the proposed synchronization approach

PEMBERIAN BONUS KEPADA PEKERJA DI PT. SANG HYANG SERI (PERSERO DALAM RANGKA MENINGKATKAN PRODUKTIVITAS KERJA DITINJAU DARI UNDANG-UNDANG NOMOR 13 TAHUN 2003 TENTANG KETENAGAKERJAAN

Directory of Open Access Journals (Sweden)

Rani Apriani, S.E., S.H., M.H.

2016-05-01

Full Text Available Workers primary motivation to do a job is to earn wages as agreed on the contract, but sometimes, the wages has some issue, one of which is when thethe worker felt that they already produce the job exceed the standard worker. Bonus classified as non-wage income provided by the company in order to encourage workers to be more discipline, industrious, productive, and increase the workers earning in PT. Sang Hyang Seri. The purpose of this research was to examine the rule used by PT. Sang Hyang Seri when giving bonuses to increase productivity and to examine the bonus implementation in PT. Sang Hyang Seri comply with Act Number 3 on 2013 related with employment.

Manuscripts on foundation of Korea nuclear power

International Nuclear Information System (INIS)

Park, Ik Su

1999-12-01

It is comprised of the manuscripts and recollections on foundation of Korea nuclear power, which includes conversation with Yoon, Se Won, conversation with Choe, Paeng Seop, conversation with Lee, Dong Jip, conversation with Lee, Sang Su, conversation with Kim, Jong Ju, conversation with Lee, Jong Hun, conversation with Youn, Yong Ryeok, conversation with Han, Pil Sun, recollection of my nuclear power by Lee, Chang Gun, recollection of safety regulation in early nuclear power by An, Yeong Ju, recollection of nuclear business in early nuclear power by Lee, Min Ha, recollection of non destructive examination by Je, Hauk, extra story related nuclear power in early period by Heo, Nam and nuclear power and I by Park,Ik Su.

One-loop renormalization of Lee-Wick gauge theory

International Nuclear Information System (INIS)

Grinstein, Benjamin; O'Connell, Donal

2008-01-01

We examine the renormalization of Lee-Wick gauge theory to one-loop order. We show that only knowledge of the wave function renormalization is necessary to determine the running couplings, anomalous dimensions, and vector boson masses. In particular, the logarithmic running of the Lee-Wick vector boson mass is exactly related to the running of the coupling. In the case of an asymptotically free theory, the vector boson mass runs to infinity in the ultraviolet. Thus, the UV fixed point of the pure gauge theory is an ordinary quantum field theory. We find that the coupling runs more quickly in Lee-Wick gauge theory than in ordinary gauge theory, so the Lee-Wick standard model does not naturally unify at any scale. Finally, we present results on the beta function of more general theories containing dimension six operators which differ from previous results in the literature.

Wrong vertex displacements due to Lee-Wick resonances at LHC

International Nuclear Information System (INIS)

Alvarez, E.; Schat, C.; Rold, L. da; Szynkman, A.

2009-01-01

We show how a resonance from the recently proposed Lee-Wick Standard Model could lead to wrong vertex displacements at LHCb. We study which could be the possible 'longest lived' Lee-Wick particle that could be created at LHC, and we study its possible decays and detections. We conclude that there is a region in the parameter space which would give wrong vertex displacements as a unique signature of the Lee-Wick Standard Model at LHCb. Further numerical simulation shows that LHC era could explore these wrong vertex displacements through Lee-Wick leptons below 500 GeV. (author)

En integrativ terapeutisk anvendelse af sang med udgangspunkt i neuropsykologiske, psykofysiologiske og psykodynamiske teorier

DEFF Research Database (Denmark)

Ridder, Hanne Mette Ochsner

2007-01-01

Hvordan kan terapeutiske forløb tilrettelægges så klienter med svære neurologiske forstyrrelser, fx mennesker med en demenssygdom, kan opnå en form for indsigt og terapeutisk forandring? Dette spørgsmål søges besvaret ved at beskrive anvendelsen af sang i den terapeutiske relation ud fra neuropsy...

Retrospective: Ivy Lee and the German Dye Trust.

Science.gov (United States)

Hainsworth, Brad E.

1987-01-01

Examines the relationship between public relations trailblazer Ivy Lee and the German Dye Trust, which became an agent for the policies of Adolf Hitler. Discusses how Lee's efforts to use this relationship to persuade his contacts to influence the Nazi leadership failed because of his formal connection with this group. (JD)

Carence en fer, anémie et anémie ferriprive chez les donneurs de sang à Kinshasa, République Démocratique du Congo

Science.gov (United States)

Nzengu-Lukusa, Franck; Yuma-Ramazani, Sylvain; Sokolua-Mvika, Eddy; Dilu-Keti, Angèle; Malenga-Nkanga, Blanchard; Shuli, Jean Baptiste; Nzongola-Nkasu, Donatien Kayembe; Mbayo-Kalumbu, Ferdinand; Ahuka-Mundeke, Steve

2016-01-01

Introduction En République Démocratique du Congo (RDC), plus d'un million de don de sang ont été réalisés entre 2007 et 2011. Cependant, aucun bilan portant sur la carence en fer et l'anémie ferriprive, conséquence d'un don de sang chez les donneurs de sang (DS), n'est disponible dans ce pays. L'objectif de cette étude était d'estimer la prévalence de la carence en fer, de l'anémie et de l'anémie ferriprive chezles DS au Centre National de Transfusion Sanguine (CNTS) à Kinshasa en RDC. Méthodes Entre Décembre 2012 et Août 2013, une étude transversale a été menée au CNTS où des DS éligibles au don de sang ont été inclus. Les informations socio démographiques et des prélèvements sanguins ont été collectés de manière simultanée au don de sang. La ferritine sérique a été dosée pour évaluer la carence en fer en utilisant la technique ELISA. L'hémogramme a été réalisé en vue d’évaluer et mettre au point l'anémie. Résultats Au total 386 DS ont été inclus dans cette étude. La prévalence de la carence en fer et de l'anémie ferriprive étaient respectivement de 63,2% (244/386) et 25,9% (100/386) des DS. Une anémie a été trouvée chez 36.5% (141/386) au moment du don de sang. Conclusion La carence en fer, l'anémie et l'anémie ferriprive demeurent très fréquentes chez les DS à Kinshasa. Ces résultats suggèrent la révision des tests biologiques utilisés dans le recrutement des DS au CNTS. Par ailleurs le dosage de la ferritine s'impose en routine chez les DS rég PMID:27303590

Baikov-Lee representations of cut Feynman integrals

International Nuclear Information System (INIS)

Harley, Mark; Moriello, Francesco; Schabinger, Robert M.

2017-01-01

We develop a general framework for the evaluation of d-dimensional cut Feynman integrals based on the Baikov-Lee representation of purely-virtual Feynman integrals. We implement the generalized Cutkosky cutting rule using Cauchy’s residue theorem and identify a set of constraints which determine the integration domain. The method applies equally well to Feynman integrals with a unitarity cut in a single kinematic channel and to maximally-cut Feynman integrals. Our cut Baikov-Lee representation reproduces the expected relation between cuts and discontinuities in a given kinematic channel and furthermore makes the dependence on the kinematic variables manifest from the beginning. By combining the Baikov-Lee representation of maximally-cut Feynman integrals and the properties of periods of algebraic curves, we are able to obtain complete solution sets for the homogeneous differential equations satisfied by Feynman integrals which go beyond multiple polylogarithms. We apply our formalism to the direct evaluation of a number of interesting cut Feynman integrals.

Thomas George Lee - Implantation and early development of North American rodents

DEFF Research Database (Denmark)

Carter, Anthony Michael

2011-01-01

A century ago Thomas G. Lee amassed an unparalleled collection of developmental series of North American rodents such as the thirteen-lined ground squirrel, the Plains pocket gopher and Merriam's kangaroo rat. He was the first to describe the initial attachment of the squirrel blastocyst to the a......A century ago Thomas G. Lee amassed an unparalleled collection of developmental series of North American rodents such as the thirteen-lined ground squirrel, the Plains pocket gopher and Merriam's kangaroo rat. He was the first to describe the initial attachment of the squirrel blastocyst...... to the antimesometrial side of the uterus. The full potential of Lee's material was not realized until after his death, when it came into the possession of Mossman. The latter relied heavily on Lee's collection when writing his seminal monograph on the comparative morphogenesis of fetal membranes and much of Lee...

Tim Berners-Lee and Kofi Annan during the WSIS

CERN Multimedia

Patrice Loïez

2003-01-01

During the 2003 World Summit on the Information Society (WSIS) at Geneva Palexpo, Tim Berners-Lee W3C's director (World Wide Web consortium) was introduced to Kofi Annan, Secretary General of the United Nations. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

Tim Berners-Lee and Kofi Annan during the WSIS

CERN Multimedia

Patrice Loïez

2003-01-01

During the 2003 World Summit on the Information Society (WSIS) at Geneva Palexpo, Tim Berners-Lee, W3C's director (World Wide Web consortium) was introduced to Kofi Annan, Secretary General of the United Nations. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

An Homage to the Bleak and Dismal World

Directory of Open Access Journals (Sweden)

Kim Yerim

2016-12-01

Full Text Available Han Kee Hyung and Lee Hye-Ryoung, eds. Chŏsuha ŭi sigan: Yŏm Sang-sŏp ŭl ikta 저수하의 시간, 염상섭을 읽다 [Time under the heaven tree: Reading Yŏm Sang-sŏp]. Seoul: Somyŏng ch’ulp’an, 2014. ISBN: 9788956265896. Heaven Tree offers justifiable and zealous attempts to commemorate Yŏm Sang-sŏp as a remarkable subject, one who was most acutely aware of the politics, society, and aesthetics of the period in which he lived. In addition, the twenty scrupulously researched and enlightening articles included in the collection unfold this attempt in a brilliant fashion, harking back to two earlier studies by Lee Bo-young and Kim Yun-sik. Those earlier books are the productive “ancestors” of Heaven Tree, in that the depth and magnitude of their reconstruction and reevaluation of Yŏm’s thoughts are analogous to what is achieved in this new collection. Nonetheless, as much as Heaven Tree is similar to its ancestors in terms of the passion and meticulousness demonstrated by the contributing authors, it proves to be a courageous offspring, as the authors further absorb, complement, and renew the existing research...

Deterministic and stochastic trends in the Lee-Carter mortality model

DEFF Research Database (Denmark)

Callot, Laurent; Haldrup, Niels; Kallestrup-Lamb, Malene

The Lee and Carter (1992) model assumes that the deterministic and stochastic time series dynamics loads with identical weights when describing the development of age specific mortality rates. Effectively this means that the main characteristics of the model simplifies to a random walk model...... that characterizes mortality data. We find empirical evidence that this feature of the Lee-Carter model overly restricts the system dynamics and we suggest to separate the deterministic and stochastic time series components at the benefit of improved fit and forecasting performance. In fact, we find...... that the classical Lee-Carter model will otherwise over estimate the reduction of mortality for the younger age groups and will under estimate the reduction of mortality for the older age groups. In practice, our recommendation means that the Lee-Carter model instead of a one-factor model should be formulated...

Lee de Forest King of Radio, Television, and Film

CERN Document Server

Adams, Mike

2012-01-01

Lee de Forest, Yale doctorate and Oscar winner, gave voice to the radio and the motion picture. Yet by the 1930s, after the radio and the Talkies were regular features of American life, Lee de Forest had seemingly lost everything. Why? Why didn’t he receive the recognition and acclaim he sought his entire life until years later in 1959, when he was awarded an Oscar? A lifelong innovator, Lee de Forest invented the three-element vacuum tube which he developed between 1906 and 1916 as a detector, amplifier, and oscillator of radio waves. As early as 1907, he was broadcasting music programming. In 1918, he began to develop a system for recording and playing back sound by using light patterns on motion picture film. In order to promote and demonstrate his process he made hundreds of short sound films, found theatres for their showing, and issued publicity to gain audiences for his invention. While he received many patents for this technology, he was ignored by the film industry. Lee de Forest, King of Radio, Te...

1.6. The kinetics of hydrochloric acid decomposition of argillite of Chashma-Sang Deposit

International Nuclear Information System (INIS)

Mirsaidov, U.M.; Mirzoev, D.Kh.; Boboev, Kh.E.

2016-01-01

Present article of book is devoted to kinetics of hydrochloric acid decomposition of argillite of Chashma-Sang Deposit. It was defined that with temperature increasing the extraction rate of Al_2O_3 and Fe_2O_3 increases. The dependence of extraction rate of Al_2O_3 and Fe_2O_3 on process duration at hydrochloric acid decomposition of argillite was studied. The activation energy of the process was defined.

TRANSFORMASI PEWAYANGAN DALAM TOKOH WISANGGENI SEBUAH ANALISIS INTERTEKSTUAL NOVEL WISANGGENI SANG BURONAN KARYA SENO GUMIRA ADJIDARMA DENGAN KOMIK LAHIRNYA BANGBANG WISANGGENI KARYA RA. KOSASIH

Directory of Open Access Journals (Sweden)

Mila Kurnia Sari

2017-10-01

Abstract This study aims to reveal the intertextuality relationship between the novel Wisanggeni Sang Buronan by Seno Gumira Adjidarma and Lahirnya Bangbang Wisanggeni by  of R.A. Kosasih in the context of Indonesiaan today. This type of research is qualitative approach using content analysis. Data collected by inventory events such as the similarities and differences of both text and see the transformation of the puppet in the text. The research results indicate first, Wisanggeni Sang Buronan  by Seno Gumira Adjidarma can be interpreted as a social critic. Seno Gumira Adjidarma signaled to readers that characters like  Wisanggeni indispensable in this country. Second, Wisanggeni, in the novel Wisanggeni Sang Buronan and  Comics Lahirnya Bangbang Wisanggeni by R.A Kosasih has a very strong character. And third, Seno Gumira Adjidarma presents the figure Wisanggeni in different forms such as  presented by RA. Kosasih in Lahirnya Bangbang Wisanggeni by  Seno Gumira Adjidarma want to re-introduce Wisanggeni as a knight in the puppet is also example in courage. Keywords: Transformation, Pupets, Novels, Comics, Intertektualitas.

Virginia Lee Burton's "Little House" in Popular Consciousness

DEFF Research Database (Denmark)

Goddard, Joseph

2011-01-01

This article considers the significance of Victoria Lee Burton’s authorship, specifically The Little House, for lifestyle preferences and the development of environmental consciousness in the postwar period. The article argues that Burton deliberately designed her work to evoke country-friendly s......This article considers the significance of Victoria Lee Burton’s authorship, specifically The Little House, for lifestyle preferences and the development of environmental consciousness in the postwar period. The article argues that Burton deliberately designed her work to evoke country...

Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers

OpenAIRE

Yoon, Seonghae; Lee, Howard; Kim, Tae-Eun; Lee, SeungHwan; Chee, Dong-Hyun; Cho, Joo-Youn; Yu, Kyung-Sang; Jang, In-Jin

2014-01-01

Seonghae Yoon,1,* Howard Lee,2,* Tae-Eun Kim,1 SeungHwan Lee,1 Dong-Hyun Chee,3 Joo-Youn Cho,1 Kyung-Sang Yu,1 In-Jin Jang1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, 2Clinical Trials Center, Seoul National University Hospital, 3AbbVie Ltd., Seoul, Republic of Korea *These authors contributed equally to this work Background: This study was conducted to compare the oral bioavailability of an itopride extended-release (ER...

Delphine Letort, The Spike Lee Brand: A Study of Documentary Filmmaking

OpenAIRE

Lipson, David

2017-01-01

Spike Lee is known the world over for films like She’s Gotta Have It (1986), School Daze (1988), Do the Right Thing (1989), etc. This association with fiction films is so strong that one could mistakenly think that Delphine Letort’s book The Spike Lee Brand: A Study of Documentary Filmmaking would explore the connection between these fiction films and the documentary genre. However, the first pages of the book clearly indicate that it will focus on Spike Lee the documentary filmmaker. Making ...

[The medical theory of Lee Je-ma and its character].

Science.gov (United States)

Lee, Kyung-Lock

2005-12-01

Lee Je-ma 1837-1900) was a prominent scholar as well as an Korean physician. classified every people into four distinctive types: greater yang [tai yang] person, lesser yin [shao yin] person, greater yin [tai yin] person, lesser yin [shao yin] person. This theory would dictate proper treatment for each type in accordance with individual differences of physical and temperament features. Using these four types he created The Medical Science of Four Types. This article is intended to look into the connection between Lee Je-Ma's 'The Medical Science of Four Types' and 'The Modern' with organizing his ideas about the human body and the human being. Through The Modern, the theory of human being underwent a complete change. Human being in The Premodern, which was determined by sex, age and social status has been changed to the individual human being, which is featured by equality. Lee Je-Ma's medical theory of The Medical Science of Four Types would be analyzed as follow. His concept of human body is oriented toward observable objectivity. But on the other hand, it still remains transcendent status of medical science, which is subordinated by philosophy. According to Lee Je-Ma's theory of human being, human is an equal individual in a modern way of thinking, not as a part of hierarchical group. But on the other hand, it still remains incomplete from getting rid of morality aspect that includes virtue and vice in the concept of human body. The common factors in Lee Je-Ma's ideas about the human body and the human being is 'Dualism of mind and body that means all kinds of status and results depends on each individual. As is stated above, Lee Je-Ma's medical theory has many aspects of The Modern and it proves that Korean traditional medicine could be modernized by itself.

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics. SANG-HAK LEE. Articles written in Journal of Genetics. Volume 96 Issue 6 December 2017 pp 1041-1046 Research article. Genome-based exome sequencing analysis identifies GYG1, DIS3L and DDRGK1 are associated with myocardial infarction in Koreans · JI-YOUNG LEE ...

Prevalência dos tipos sangüíneos A, B e AB em gatos domésticos mestiços da cidade de Porto Alegre, Rio Grande do Sul, Brasil

Directory of Open Access Journals (Sweden)

Luciana de Almeida Lacerda

2008-12-01

Full Text Available O presente estudo teve como objetivo determinar a prevalência dos tipos sangüíneos em felinos domésticos, mestiços, da cidade de Porto Alegre, Rio Grande do Sul, Brasil. Foram selecionados aleatoriamente 100 gatos, clinicamente saudáveis, mestiços e sem parentesco entre si. Amostras de sangue foram coletadas da veia jugular e a tipagem sangüínea foi realizada através do teste RapidVet H Feline (DMS Laboratories, Flemington, USA e do teste hemaglutinação em tubo de ensaio. A tipagem reversa foi realizada para confirmar o tipo e a presença de aloanticorpos naturais. No presente estudo encontrou-se prevalência de 97% e 3% de gatos do tipo A e B, respectivamente. Não foram encontrados gatos do tipo AB. Os resultados indicam que no sul do Brasil há uma alta prevalência de gatos domésticos mestiços do tipo A, entretanto a prevalência de gatos do tipo B encontrada no trabalho é mais alta do que aquelas relatadas em alguns países. O conhecimento da prevalência dos tipos sangüíneos da população de gatos de uma região pode auxiliar na determinação dos riscos de reações transfusionais e de ocorrência de isoeritrólise neonatal, e estes podem ser prevenidos através de tipagem sangüínea e teste de compatibilidade sangüínea.

Docetaxel-loaded multilayer nanoparticles with nanodroplets for cancer therapy

OpenAIRE

Oh, Keun Sang; Kim, Kyungim; Yoon, Byeong Deok; Lee, Hye Jin; Park, Dal Yong; Kim, Eun-yeong; Lee, Kiho; Seo, Jae Hong; Yuk, Soon Hong

2016-01-01

Keun Sang Oh,1,* Kyungim Kim,1,* Byeong Deok Yoon,1 Hye Jin Lee,1 Dal Yong Park,1 Eun-yeong Kim,1 Kiho Lee,1 Jae Hong Seo,2 Soon Hong Yuk1,2 1College of Pharmacy, Korea University, Sejong, 2Biomedical Research Center, Korea University Guro Hospital, Guro-gu, Seoul, Republic of Korea *These authors contributed equally to this work Abstract: A mixture of docetaxel (DTX) and Solutol® HS 15 (Solutol) transiently formed nanodroplets when it was suspended in an aqueous medium. However, n...

Optimization of biohydrogen production from beer lees using anaerobic mixed bacteria

Energy Technology Data Exchange (ETDEWEB)

Cui, Maojin; Yuan, Zhuliang; Zhi, Xiaohua; Shen, Jianquan [Beijing National Laboratory for Molecular Sciences (BNLMS), Laboratory of New Materials, Institute of Chemistry, Chinese Academy of Sciences, Zhongguancun North First Street 2, Beijing 100190 (China)

2009-10-15

Beer lees are the main by-product of the brewing industry. Biohydrogen production from beer lees using anaerobic mixed bacteria was investigated in this study, and the effects of acidic pretreatment, initial pH value and ferrous iron concentration on hydrogen production were studied at 35 C in batch experiments. The hydrogen yield was significantly enhanced by optimizing environmental factors such as hydrochloric acid (HCl) pretreatment of substrate, initial pH value and ferrous iron concentration. The optimal environmental factors of substrate pretreated with 2% HCl, pH = 7.0 and 113.67 mg/l Fe{sup 2+} were observed. A maximum cumulative hydrogen yield of 53.03 ml/g-dry beer lees was achieved, which was approximately 17-fold greater than that in raw beer lees. In addition, the degradation efficiency of the total reducing sugar, and the contents of hemicellulose, cellulose, lignin and metabolites are presented, which showed a strong dependence on the environmental factors. (author)

Awards: New Year Knighthood for Tim Berners-Lee

CERN Multimedia

2004-01-01

Tim Berners-Lee has been awarded his country's highest honour - a knighthood - in the UK's New Year Honours list for his work while at CERN on the World Wide Web. In the same honours list, Roger Cashmore has been made a Companion of the Order of St Michael and St George (CMG) "for his services to international co-operation in particle physics". Cashmore was CERN's Director for Collider Programmes from 1999-2003, and is now Principal of Brasenose College, Oxford. Tim Berners-Lee stands in front of the first web server at Palexpo during the World Summit on the Information Society.

Lee-Nauenberg theorem and Coulomb scattering

Energy Technology Data Exchange (ETDEWEB)

Fleming, H; Frenkel, J [Sao Paulo Univ. (Brazil). Instituto de Fisica

1975-08-01

Lee-Nauenberg analysis is extended to the case of Coulomb scattering, where the diagonal elements of the Hamiltonian interaction are singular functions. It is shown, using a simple argument, that the leading infrared singularities in the cross-section are mutually canceled out.

Grain-size sorting in grainflows at the lee side of deltas

NARCIS (Netherlands)

Kleinhans, M.G.

2005-01-01

The sorting of sediment mixtures at the lee slope of deltas (at the angle of repose) is studied with experiments in a narrow, deep flume with subaqueous Gilbert-type deltas using varied flow conditions and different sediment mixtures. Sediment deposition and sorting on the lee slope of the delta

The medical theory of Lee Je-ma and its character

Directory of Open Access Journals (Sweden)

LEE Kyung-Lock

2005-12-01

Full Text Available Lee Je-ma(李濟馬, 1837-1900 was a prominent scholar as well as an Korean physician He classified every people into four distinctive types: greater yang[tai yang] person, lesser yin[shao yin] person greater yin[tai yin] person, lesser yin[shao yin] person. This theory would dictate proper treatment for each type in accordance with individual differences of physical and temperament features Using these four types he created The Medical Science of Four Types(四象體質論.This article is intended to look into the connection between Lee Je-Ma's 'The Medical Science of Four Types' and 'The Modern' with organizing his ideas about the human body and the human being. Through The Modern, the theory of human being(人間觀 underwent a complete change. Human being in The Premodern, which was determined by sex, age and social status has been changed to the individual human being, which is featured by equality. Lee Je-Ma's medical theory of The Medical Science of Four Types would be analyzed as follow. His concept of human body(人體論 is oriented toward observable objectivity. But on the other hand, it still remains transcendent status of medical science, which is subordinated by philosophy According to Lee Je-Ma's theory of human being human is an equal individual in a modern way of thinking not as a part of hierarchical group. But on the other hand, it still remains incomplete from getting rid of morality aspect that includes virtue and vice in the concept of human body.The common factors in Lee Je-Ma's ideas about the human body and the human being is 'Dualism of mind and body(心身二元論' that means all kinds of status and results depends on each individual. As is stated above, Lee Je-Ma's medical theory has many aspects of The Modern and it proves that Korean traditional medicine could be modernized by itself.

Influence du temps de conservation du sang sur l'hémogramme réalisé avec le Vet-ABC chez le chien et le chat

OpenAIRE

Caillard, Agnès

2002-01-01

L'utilisation du Vet abc, automate d'hématologie de type «coulter » a permis d'étudier les modifications engendrées par la conservation du sang pendant 24 heures à température ambiante, sur les paramètres et constituants de l'hémogramme du chien et du chat. L'évaluation de l'effet de la conservation du sang sur l'IDR et sur les courbes de distribution cellulaire, constitue l'originalité de ce travail. Les évolutions les plus notables ont été les suivantes : - un VGM qui augmente en moyenne de...

Tim Berners-Lee at the RSIS conference from 8-9 December 2003.

CERN Multimedia

Patrice Loiez

2003-01-01

Tim Berners-Lee participated in the Role of Science in the Information Society conference held at CERN from 8-9 December 2003. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

Subordinations In “To Kill A Mockingbird” By Harper Lee

OpenAIRE

Siregar, Rut Sri Novitawaty

2011-01-01

Salah satu yang dipelajari mahasiswa adalah tulis menulis. Secara ilmiah tulis menulis adalah penyampaian informasi dalam bentuk tulisan serta bagaimana informasi itu disampaikan. Judul kertas karya ini adalah Kalimat Subordinat yang ditemukan dalam novel To Kill a Mockingbird karya Harper Lee: SUBORDINATION IN TO KILL A MOCKINGBIRD BY HARPER LEE. Penulis mengangkat hal ini karena penulis tertarik dengan bentuk–bentuk serta fungsi-fungsi kalimat subordinat yang terdapat dalam tulisan-tulisan ...

Instability of the Lee-Wick bounce

International Nuclear Information System (INIS)

Karouby, Johanna; Brandenberger, Robert; Qiu, Taotao

2011-01-01

It was recently realized [Y. F. Cai, T. t. Qiu, R. Brandenberger, and X. m. Zhang, Phys. Rev. D 80, 023511 (2009).] that a model constructed from a Lee-Wick type scalar field theory yields, at the level of homogeneous and isotropic background cosmology, a bouncing cosmology. However, bouncing cosmologies induced by pressureless matter are in general unstable to the addition of relativistic matter (i.e. radiation). Here we study the possibility of obtaining a bouncing cosmology if we add radiation coupled to the Lee-Wick scalar field. This coupling in principle would allow the energy to flow from radiation to matter, thus providing a drain for the radiation energy. However, we find that it takes an extremely unlikely fine-tuning of the initial phases of the field configurations for a sufficient amount of radiative energy to flow into matter. For general initial conditions, the evolution leads to a singularity rather than a smooth bounce.

Lee waves, benign and malignant

Science.gov (United States)

Wurtele, M. G.; Datta, A.

1992-01-01

The flow of an incompressible, stratified fluid over an obstacle will produce an oscillation in which buoyancy is the restoring force, called a gravity wave. For disturbances of this scale, the atmosphere may be treated as incompressible; and even the linear approximation will explain many of the phenomena observed in the lee of mountains. However, nonlinearities arise in two ways: (1) through the large (scaled) size of the mountain, and (2) from dynamically singular levels in the fluid field. These produce a complicated array of phenomena that present hazards to aircraft and to lee surface areas. If there is no dynamic barrier, these waves can penetrate vertically into the middle atmosphere (30-100 km attitude), where recent observations show them to be of a length scale that must involve the Coriolis force in any modeling. At these altitudes, the amplitude of the waves is very large, and the waves are studied with a view to their potential impact on the projected National Aerospace Plane. This paper presents the results of analyses and state-of-the-art numerical simulations, validated where possible by observational data.

The Statecraft of Singapore's Lee Kuan Yew

National Research Council Canada - National Science Library

Toh, K

1996-01-01

.... The ejection of Singapore from the Federation led Lee to focus on two strategic goals: the survival of Singapore as an independent state while simultaneously pursuing nation-building under the threats of communism and internal ethnic conflicts...

Triniti daripada Perspektif Taoisme: Analisis Pemikiran Jung Young Lee

Directory of Open Access Journals (Sweden)

ZURAIZA HUSIN

2016-06-01

Full Text Available Jung Young Lee is a Korean-born theologian who employs creatively the doctrine of the Trinity from an Asian worldview. This article aims to analyze Lee’s approaches of the Trinity with the Yin-Yang symbolism. The main reference is based on the book written by him entitled ‘The Trinity in Asian Perspective (1996’. Lee has turned his attention to the topic of Trinity through the lens of the culture and thought patterns of his own milieu. One of the leading point in presenting Yin-Yang principle as Trinitarian thinking, Lee examines the interpretation of the term “in” in the Bible, "Believe me that I am in the Father and the Father is in me" (John 14:11. The statement leads to the point that Yin and Yang cannot exist without each other because relationality is given priority than individuality. The idea is based on the terminology of ‘both/and’. So, ‘and’ indicates a Trinitarian statement, there is interdependence and unification. With reference to Trinity, the Father and the Son are One because of ‘and’. In addition, the same concept implements to the Holy Spirit. Lee views ‘and’ is not only a linking principle in both-and thinking but also the principle that is ‘between’ two. When ‘two’ exists, the third also exist between them. Based on the idea of ‘middle’, represents the connecting element between two, which contributes for the existence of the Third. Accordingly, the Spirit is the third element in the Trinity relationship.

Comparative genomics and stx phage characterization of LEE-negative Shiga toxin-producing Escherichia coli

Directory of Open Access Journals (Sweden)

Susan Renee Steyert

2012-11-01

Full Text Available Infection by Escherichia coli and Shigella species are among the leading causes of death due to diarrheal disease in the world. Shiga toxin producing Escherichia coli (STEC that do not encode the locus of enterocyte effacement (LEE-negative STEC often possess Shiga toxin gene variants and have been isolated from humans and a variety of animal sources. In this study, we compare the genomes of nine LEE-negative STEC harboring various stx alleles with four complete reference LEE-positive STEC isolates. Compared to a representative collection of prototype E. coli and Shigella isolates representing each of the pathotypes, the whole genome phylogeny demonstrated that these isolates are diverse. Whole genome comparative analysis of the 13 genomes revealed that in addition to the absence of the LEE pathogenicity island, phage encoded genes including non-LEE encoded effectors, were absent from all nine LEE-negative STEC genomes. Several plasmid-encoded virulence factors reportedly identified in LEE-negative STEC isolates were identified in only a subset of the nine LEE-negative isolates further confirming the diversity of this group. In combination with whole genome analysis, we characterized the lambdoid phages harboring the various stx alleles and determined their genomic insertion sites. Although the integrase gene sequence corresponded with genomic location, it was not correlated with stx variant, further highlighting the mosaic nature of these phages. The transcription of these phages in different genomic backgrounds was examined. Expression of the Shiga toxin genes, stx1 and/or stx2, as well as the Q genes, were examined with quantitative reverse transcriptase polymerase chain reaction (qRT-PCR assays. A wide range of basal and induced toxin induction was observed. Overall, this is a first significant foray into the genome space of this unexplored group of emerging and divergent pathogens.

Practical Improvements to the Lee-More Conductivity Near the Metal-Insulator Transition

International Nuclear Information System (INIS)

Desjarlais, Michael P.

2000-01-01

The wide-range conductivity model of Lee and More is modified to allow better agreement with recent experimental data and theories for dense plasmas in the metal-insulator transition regime. Modifications primarily include a new ionization equilibrium model, consisting of a smooth blend between single ionization Saha (with a pressure ionization correction) and the generic Thomas-Fermi ionization equilibrium, a more accurate treatment of electron-neutral collisions using a polarization potential, and an empirical modification to the minimum allowed collision time. These simple modifications to the Lee-More algorithm permit a more accurate modeling of the physics near the metal-insulator transition, while preserving the generic Lee-More results elsewhere

Practical improvements to the Lee-More conductivity near the metal-insulator transition

International Nuclear Information System (INIS)

Desjarlais, M.P.

2001-01-01

The wide-range conductivity model of Lee and More is modified to allow better agreement with recent experimental data and theories for dense plasmas in the metal-insulator transition regime. Modifications primarily include a new ionization equilibrium model, consisting of a smooth blend between single ionization Saha (with a pressure ionization correction) and the generic Thomas-Fermi ionization equilibrium, a more accurate treatment of electron-neutral collisions using a polarization potential, and an empirical modification to the minimum allowed collision time. These simple modifications to the Lee-More algorithm permit a more accurate modeling of the physics near the metal-insulator transition, while preserving the generic Lee-More results elsewhere. (orig.)

Tim Berners-Lee, World Wide Web inventor

CERN Multimedia

1998-01-01

The "Internet, Web, What's next?" conference on 26 June 1998 at CERN: Tim Berners-Lee, inventor of the World Wide Web and Director of the W3C, explains how the Web came to be and gave his views on the future.

Alternative implementation of the chaotic Chen-Lee system

International Nuclear Information System (INIS)

Sheu, L.-J.; Tam, L.-M.; Chen, H.-K.; Lao, S.-K.

2009-01-01

The chaotic Chen-Lee system was developed with a formalism based on the Euler equations for the motion of a rigid body. It was proved that this system is the governing set of equations for gyro motion with feedback control. Recently, studies were conducted to explore the dynamic behavior of this system, including fractional order behavior, the generation of hyperchaos and perturbation analysis, control and anti-control of chaos, synchronization, etc. In this study, we further explore (1) the stability of the equilibrium points and (2) the implementation of an electronic circuit using the Chen-Lee system. It is shown that not only is this system related to gyro motion but can also be applied to electronic circuits for encryption purposes.

Courtland Lee: A Global Advocate for Counseling

Science.gov (United States)

Gladding, Samuel T.

2011-01-01

Courtland Lee is exemplary in his accomplishments nationally and internationally. His academic achievements are notable in multicultural counseling and social justice. His leadership in counseling has been outstanding with his having served as president of the American Counseling Association, the Association for Multicultural Counseling and…

Nooruslikud juubilarid: fotokelder Lee 20 ja fotomuuseum 30 / Mall Parmas, Betty Ester-Väljaots

Index Scriptorium Estoniae

Parmas, Mall

2013-01-01

Peeter Toominga algatusel 1992. aastal asutatud Lee fotokeldrist. Loetletud fotomuuseumis oma töid eksponeerinud fotograafid. Ülevaatenäitus "Lee fotokelder 20" 17. jaanuarist 20. märtsini, koostaja Betty Ester-Väljaots

Synchronization and anti-synchronization coexist in Chen-Lee chaotic systems

International Nuclear Information System (INIS)

Chen, J.-H.; Chen, H.-K.; Lin, Y.-K.

2009-01-01

This study demonstrates that synchronization and anti-synchronization can coexist in Chen-Lee chaotic systems by direct linear coupling. Based on Lyapunov's direct method, a linear controller was designed to assure that two different types of synchronization can simultaneously be achieved. Further, the hybrid projective synchronization of Chen-Lee chaotic systems was studied using a nonlinear control scheme. The nonlinear controller was designed according to the Lyapunov stability theory to guarantee the hybrid projective synchronization, including synchronization, anti-synchronization, and projective synchronization. Finally, numerical examples are presented in order to illustrate the proposed synchronization approach.

Economist Innovation Award for Tim Berners-Lee

CERN Multimedia

2003-01-01

In September, Tim Berners-Lee, who invented the World Wide Web at CERN and is now Director of the W3C World Wide Web Consortium, received the 2nd Economist Annual Innovation Award in Computing. With the award The Economist, a British weekly newspaper, recognises individuals responsible for breakthroughs in Bioscience, Computing, Energy and the Environment, and Telecommunications that have a profound impact on industry. A fifth award is given in a special "No Boundaries" category, observing innovation that transcends industries. Candidates for the awards are proposed by The Economist readers and writers, and by a group of judges. Tim Berners-Lee received the Computing award for his global hypertext project, to be known as the World Wide Web, which "forever altered the way information is shared" and is a huge contribution to the efficiency of the scientific community. Based on a programme for storing information using random associations called "Enquire", it...

[Lee Jungsook, a Korean independence activist and a nurse during the Japanese colonial period].

Science.gov (United States)

Kim, Sook Young

2015-04-01

This article examines the life of Lee Jungsook, a Korean nurse, as a independence activist during the Japanese colonial period. Lee Jungsook(1896-1950) was born in Bukchung in Hamnam province. She studied at Chungshin girl's high school and worked at Severance hospital. The characteristics and culture of her educational background and work place were very important factors which influenced greatly the life of Lee Jungsook. She learned independent spirit and nationalism from Chungshin girls' high school and worked as nurse at the Severance hospital which were full of intense aspiration for Korea's independence. Many of doctors, professors and medical students were participated in the 3.1 Independence Movement. Lee Jungsook was a founding member of Hyulsungdan who tried to help the independence activists in prison and their families and worked as a main member of Korean Women's Association for Korean Independece and Kyungsung branch of the Korean Red Cross. She was sent to jail by the Japanese government for her independence activism. After being released after serving two years confinement, she worked for the Union for Women's Liberation as a founding member. Lee Joungsook was a great independence activist who had a nursing care spirit as a nurse.

Test procedure for the Master-Lee and the modified Champion four inch hydraulic cutters

International Nuclear Information System (INIS)

Crystal, J.B.

1995-01-01

The Master-Lee and the modified Champion 4 Inch hydraulic cutters are being retested to gather and document information related to the following: determine if the Master-Lee cutters will cut the trunnions of an Aluminum fuel canister and a Stainless Steel fuel canister; determine if the Master-Lee cutters will cut 1 1/2 inch diameter fire hose; determine if the modified Champion 4 inch blade will cut sections of piping; and determine the effectiveness of the centering device for the Champion 4 Inch cutters. Determining the limitations of the hydraulic cutter will aid in the process of debris removal in the K-Basin. Based on a previous test, the cutters were returned to the manufacturer for modifications. The modifications to the Champion 4 Inch Cutter and further testing of the Master-Lee Cutter are the subjects of these feature tests

Parametric study of the fractional-order Chen-Lee system

International Nuclear Information System (INIS)

Tam, L.M.; Tou, W.M.S.

2008-01-01

The dynamics of fractional-order systems have attracted a great deal of attention in recent years. In this paper, the effects of parameter changes on the dynamics of the fractional-order Chen-Lee system were studied numerically. The parameter ranges used were relatively broad. The order used for the system was fixed at 2.7 (q 1 = q 2 = q 3 = 0.9). The system displays rich dynamic behaviors, such as a fixed point, periodic motion (including period-3 motion), chaotic motion, and transient chaos. The chaotic motion identified was validated by the confirmation of a positive Lyapunov exponent. Period-doubling routes to chaos in the fractional-order Chen-Lee system were also found

Lee Acculturation Dream Scale for Korean-American college students.

Science.gov (United States)

Lee, Sang Bok

2005-04-01

This study examined acculturation as represented in dream narratives of 165 Korean immigrant college students living in the USA. A total of 165 dreams were collected and evaluated using the Lee Acculturation Dream Scale, for which locations of dream contents were coded. 39% of the dreams took place in South Korea, while 38% were in the USA. Also, 16% of the dreams included both locations, whereas 7% had no specific dream location. The dreams contained overlapping dream messages, images, scenes, and interactions in both South Korea and the USA. A two-sample t test on the mean scores of the Lee Acculturation Dream Scale indicated no significant difference between men and women.

Parametric study of the fractional-order Chen-Lee system

Energy Technology Data Exchange (ETDEWEB)

Tam, L.M. [Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Av. Padre Tomas Pereira S.J., Taipa, Macau (China)], E-mail: fstlmt@umac.mo; Tou, W.M.S. [Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Av. Padre Tomas Pereira S.J., Taipa, Macau (China)

2008-08-15

The dynamics of fractional-order systems have attracted a great deal of attention in recent years. In this paper, the effects of parameter changes on the dynamics of the fractional-order Chen-Lee system were studied numerically. The parameter ranges used were relatively broad. The order used for the system was fixed at 2.7 (q{sub 1} = q{sub 2} = q{sub 3} = 0.9). The system displays rich dynamic behaviors, such as a fixed point, periodic motion (including period-3 motion), chaotic motion, and transient chaos. The chaotic motion identified was validated by the confirmation of a positive Lyapunov exponent. Period-doubling routes to chaos in the fractional-order Chen-Lee system were also found.

Sex, Adiposity, and Hypertension Status Modify the Inverse Effect of Marine Food Intake on Blood Pressure in Alaska Native (Yup'ik) People.

Science.gov (United States)

Beaulieu-Jones, Brendin R; O'Brien, Diane M; Hopkins, Scarlett E; Moore, Jason H; Boyer, Bert B; Gilbert-Diamond, Diane

2015-05-01

Alaska Native people currently have a higher prevalence of hypertension than do nonnative Alaskans, although in the 1950s hypertension was rare among Alaska Native people. A novel biomarker of marine foods, the nitrogen isotope ratio (δ¹⁵N) in RBCs was shown to be negatively associated with systolic and diastolic blood pressure. Few studies have examined how individual characteristics modify the association of marine food intake with blood pressure. This exploratory analysis examined whether sex, adiposity, and hypertension modify the inverse association between marine food intake and blood pressure. We used covariate-adjusted linear models to describe the association between δ¹⁵N and blood pressure in 873 adult Alaska Native (Yup'ik) people who resided in 8 communities in southwest Alaska. We separately stratified by sex, body mass index (BMI) group, abdominal obesity, and hypertension status and assessed the interaction between δ¹⁵N and participant characteristics on blood pressure via likelihood ratio tests. The association between δ¹⁵N and systolic blood pressure was modified by sex, BMI status, and abdominal obesity, with the inverse association observed only in the male (β = -1.5; 95% CI: -2.4, -0.6 : , nonobese BMI (β = -1.7; 95% CI: -2.5, -1.0), and non-abdominally obese (β = -1.6; 95% CI: -2.4, -0.9) strata (all P-interaction blood pressure associated with δ¹⁵N was observed in the nonobese BMI (β = -1.1; 95% CI: -1.7, -0.5) and non-abdominally obese (β = -1.1; 95% CI: -1.7, -0.5) strata, although only the interaction between BMI group and δ¹⁵N with diastolic blood pressure was significant. The inverse association between δ¹⁵N and both systolic and diastolic blood pressure was observed in nonhypertensive individuals, although the comparison had limited power. The results were consistent with those identified by using combined RBC concentrations of eicosapentaenoic acid and docosahexaenoic acid as the biomarker of marine food

Una ciudad de los vascones en el yacimiento de Campo Real/Fillera (Sos del Rey Católico-Sangüesa

Directory of Open Access Journals (Sweden)

Andreu Pintado, Javier

2008-12-01

Full Text Available The following paper deals with the detailed and preliminary study of the archaeological site of Campo Real/Fillera (Sos del Rey Católico/Sangüesa, between today Zaragoza and Navarra provinces specially focusing in its Roman period. The paper exposes a review of the archeological and epigraphical material from the site, proposes an urban condition for it and raises some hypothesis on its identification with one of the cities that ancient sources tribued to Vascones.El presente trabajo aborda el estudio detallado y preliminar del yacimiento arqueológico de Campo Real/Fillera (Sos del Rey Católico/Sangüesa, en el límite entre las actuales provincias de Zaragoza y Navarra con especial atención a su etapa romana. Se procede a la revisión del material arqueológico y epigráfico procedente del lugar, se defiende la condición de enclave urbano del yacimiento y se plantea una hipótesis respecto de su identificación con las ciudades que las fuentes antiguas atribuyen a los Vascones.

Pear distillates from pear juice concentrate: effect of lees in the aromatic composition.

Science.gov (United States)

García-Llobodanin, L; Achaerandio, I; Ferrando, M; Güell, C; López, F

2007-05-02

Pear juice obtained from pear concentrate was fermented at room temperature using Saccharomyces cerevisiae (BDX, ENOFERM, France) as the fermentation microorganism. During the fermentation process, total sugars were measured. High performance liquid chromatography analyses were used to monitor the fermentation process and to characterize the pear wine. The pear wine obtained was distilled with its lees using three different equipments: a glass alembic (a glass pot still coupled to a glass column), a copper alembic, and a glass alembic with the addition of 5 g/L of copper shavings to the pot still. The same distillations were repeated with the wine without its lees (separated by decanting). Several distillation fractions were collected, up to a total of 500 mL of distillate. Gas chromatography was used to identify and quantify the volatile compounds in each fraction, and the methanol and ethanol contents. Based on these results, the heart fraction was defined. ANOVA tests were performed on the heart fractions to determine quantitative differences between some volatile compounds depending on the equipment used and the presence or absence of the wine lees. From this series of ANOVA tests, it can be concluded that the concentrations of the compounds that are considered to have a negative effect on the quality of the distillates (methanol, ethyl acetate, furfural) decrease or do not change when they are distilled in the presence of lees and in the copper alembic. In addition, the concentrations of the positive compounds (ethyl decanoate and ethyl-2-trans-4-cis-decadienoate) increase in the presence of lees for all of the equipment tested. So, it can be assumed that the distillation of pear wine with its lees in copper alembic leads to a better quality product.

Berners-Lee wins inaugural Millennium Technology prize

CERN Document Server

2004-01-01

"World Wide Web inventor Tim Berners-Lee today was named recipient of the first-ever Millennium Technology Prize. The honor, which is accompanied by one million euros, is bestowed by the Finnish Technology Award Foundation as an international acknowledgement of outstanding technological innovation aimed at promoting quality of life and sustainable economic and societal development" (1 page)

Dan Gilmor Column [Berners-Lee and the WWW

CERN Multimedia

Gillmore, D

2002-01-01

In the keynote speech at the 11th Annual World Wide Web Conference, Tim Berner's Lee said that in the early days of the web, people were worrying about the same thing as today - one company dominating the market and controlling standards (2 pages).

The Statecraft of Lee Kuan Yew, Visionary and Opportunist

National Research Council Canada - National Science Library

Thomas, David

1996-01-01

...." "Not so," replied the passenger, Lee Kuan Yew, "Singapore intends to continue to ride along as part of the federation created with Malaysia, Sarawak, and Sabah -- we have no plans for getting off...

Kajian Aspek Fotografis dalam Tehnik Olah Digital Poster Film “ Sang Pemimpi ”

Directory of Open Access Journals (Sweden)

Noor Latif CM

2011-04-01

Full Text Available As the advancement of digital imaging technology, this urges internal actors to be more accurate and explorative in producing visual communication work with photography element and digital touching process. Digital process ability with no photographical ability will produce raw and anomaly visual work of art. Besides, audience is smarter and more appreciative towards quality of visual appearance in several modern communication media. Film poster of Sang Pemimpi is a case reflection of general digital in visual communication work that has gap among communication product content according to the brand of the film. Photography element composition is melted with bondless pile among the objects. Logical photography as bonding bridge of visual logic is weak in execution; where we could see it has less digital process commercial market need with the supporting resources. 

General Robert E. Lee -- Brightest Star in the South

National Research Council Canada - National Science Library

Dalton, Kent B

2006-01-01

.... Lee's distinctive application of operational art and leadership as the commander of the Army of Northern Virginia, we can discern many lessons which are still pertinent to our commanders at the operational level today...

Observation of Mountain Lee Waves with MODIS NIR Column Water Vapor

Science.gov (United States)

Lyapustin, A.; Alexander, M. J.; Ott, L.; Molod, A.; Holben, B.; Susskind, J.; Wang, Y.

2014-01-01

Mountain lee waves have been previously observed in data from the Moderate Resolution Imaging Spectroradiometer (MODIS) "water vapor" 6.7 micrometers channel which has a typical peak sensitivity at 550 hPa in the free troposphere. This paper reports the first observation of mountain waves generated by the Appalachian Mountains in the MODIS total column water vapor (CWV) product derived from near-infrared (NIR) (0.94 micrometers) measurements, which indicate perturbations very close to the surface. The CWV waves are usually observed during spring and late fall or some summer days with low to moderate CWV (below is approx. 2 cm). The observed lee waves display wavelengths from3-4 to 15kmwith an amplitude of variation often comparable to is approx. 50-70% of the total CWV. Since the bulk of atmospheric water vapor is confined to the boundary layer, this indicates that the impact of thesewaves extends deep into the boundary layer, and these may be the lowest level signatures of mountain lee waves presently detected by remote sensing over the land.

Potential of lees from wine, beer and cider manufacturing as a source of economic nutrients: An overview.

Science.gov (United States)

Pérez-Bibbins, B; Torrado-Agrasar, A; Salgado, J M; Oliveira, R Pinheiro de Souza; Domínguez, J M

2015-06-01

Lees are the wastes generated during the fermentation and aging processes of different industrial activities concerning alcoholic drinks such as wine, cider and beer. They must be conveniently treated to avoid uncontrolled dumping which causes environmental problems due to their high content of phenols, pesticides, heavy metals, and considerable concentrations of nitrogen, phosphate and potassium as well as high organic content. The companies involved must seek alternative environmental and economic physicochemical and biological treatments for their revalorization consisting in the recovery or transformation of the components of the lees into high value-added compounds. After describing the composition of lees and market of wine, beer and cider industries in Spain, this work aims to review the recent applications of wine, beer and cider lees reported in literature, with special attention to the use of lees as an endless sustainable source of nutrients and the production of yeast extract by autolysis or cell disruption. Lees and/or yeast extract can be used as nutritional supplements with potential exploitation in the biotechnological industry for the production of natural compounds such as xylitol, organic acids, and biosurfactants, among others. Copyright © 2015 Elsevier Ltd. All rights reserved.

Quantization of the Lee static model by the Bogolyubov transformation method

International Nuclear Information System (INIS)

Bornyakov, V.G.

1984-01-01

The Lee static strong-coupling model is studied. The model permits to find an exact solution for the state vector of the system and for the scattering matrix in the first permanent order of expansion in the inverse value of the coupling constant. The Bogolyubov method has been applied to quantize the Lee model with a hamiltonian, provided a high classical constituent of a boson field exists. Ground state of the system and scattering matrix from the obtained bound state are found. The way to avoid additional zero modes arising at Bogolyubov transformation for creation and annihilation operators is shown

Co-ordinate single-cell expression of LEE4- and LEE5-encoded proteins of Escherichia coli O157:H7.

Science.gov (United States)

Roe, Andrew J; Naylor, Stuart W; Spears, Kevin J; Yull, Helen M; Dransfield, Tracy A; Oxford, Matthew; McKendrick, Iain J; Porter, Megan; Woodward, Martin J; Smith, David G E; Gally, David L

2004-10-01

Escherichia coli O157:H7 is a zoonotic pathogen that can express a type III secretion system (TTSS) considered important for colonization and persistence in ruminants. E. coli O157:H7 strains have been shown to vary markedly in levels of protein secreted using the TTSS and this study has confirmed that a high secretion phenotype is more prevalent among isolates associated with human disease than isolates shed by healthy cattle. The variation in secretion levels is a consequence of heterogeneous expression, being dependent on the proportion of bacteria in a population that are actively engaged in protein secretion. This was demonstrated by indirect immunofluorescence and eGFP fusions that examined the expression of locus of enterocyte effacement (LEE)-encoded factors in individual bacteria. In liquid media, the expression of EspA, tir::egfp, intimin, but not map::egfp were co-ordinated in a subpopulation of bacteria. In contrast to E. coli O157:H7, expression of tir::egfp in EPEC E2348/69 was equivalent in all bacteria although the same fusion exhibited variable expression when transformed into an E. coli O157:H7 background. An E. coli O157:H7 strain deleted for the LEE demonstrated weak but variable expression of tir::egfp indicating that the elements controlling the heterogeneous expression lie outside the LEE. The research also demonstrated the rapid induction of tir::egfp and map::egfp on contact with bovine epithelial cells. This control in E. coli O157:H7 may be required to limit exposure of key surface antigens, EspA, Tir and intimin during colonization of cattle but allow their rapid production on contact with bovine gastrointestinal epithelium at the terminal rectum.

The Garrett Lee Smith Memorial Suicide Prevention Program

Science.gov (United States)

Goldston, David B.; Walrath, Christine M.; McKeon, Richard; Puddy, Richard W.; Lubell, Keri M.; Potter, Lloyd B.; Rodi, Michael S.

2010-01-01

In response to calls for greater efforts to reduce youth suicide, the Garrett Lee Smith (GLS) Memorial Act has provided funding for 68 state, territory, and tribal community grants, and 74 college campus grants for suicide prevention efforts. Suicide prevention activities supported by GLS grantees have included education, training programs…

INCA Modelling of the Lee System: strategies for the reduction of nitrogen loads

Directory of Open Access Journals (Sweden)

N. J. Flynn

2002-01-01

Full Text Available The Integrated Nitrogen Catchment model (INCA was applied successfully to simulate nitrogen concentrations in the River Lee, a northern tributary of the River Thames for 1995-1999. Leaching from urban and agricultural areas was found to control nitrogen dynamics in reaches unaffected by effluent discharges and abstractions; the occurrence of minimal flows resulted in an upward trend in nitrate concentration. Sewage treatment works (STW discharging into the River Lee raised nitrate concentrations substantially, a problem which was compounded by abstractions in the Lower Lee. The average concentration of nitrate (NO3 for the simulation period 1995-96 was 7.87 mg N l-1. Ammonium (NH4 concentrations were simulated less successfully. However, concentrations of ammonium rarely rose to levels which would be of environmental concern. Scenarios were run through INCA to assess strategies for the reduction of nitrate concentrations in the catchment. The conversion of arable land to ungrazed vegetation or to woodland would reduce nitrate concentrations substantially, whilst inclusion of riparian buffer strips would be unsuccessful in reducing nitrate loading. A 50% reduction in nitrate loading from Luton STW would result in a fall of up to 5 mg N l-1 in the reach directly affected (concentrations fell from maxima of 13 to 8 mg N l-1 , nearly a 40 % reduction, whilst a 20% reduction in abstractions would reduce maximum peaks in concentration in the lower Lee by up to 4 mg l-1 (from 17 to 13 mg N l-1, nearly a 25 % reduction,. Keywords: modelling, water quality, nitrogen, nitrate, ammonium, INCA, River Lee, River Thames, land-use.

Tim Berners-Lee: inventor de la World Wide Web

OpenAIRE

Universidad de Granada. Biblioteca

2015-01-01

El presente Cat??logo contiene la exposici??n organizada por la Biblioteca de la ETSIIT de la Universidad de Granada durante los meses de noviembre-diciembre de 2015 y titulada: "Tim Berners-Lee: inventor de la World Wide Web"

Bronchoscopic lung volume reduction by endobronchial valve in advanced emphysema: the first Asian report

Directory of Open Access Journals (Sweden)

Park TS

2015-07-01

Full Text Available Tai Sun Park,1 Yoonki Hong,2 Jae Seung Lee,1 Sang Young Oh,3 Sang Min Lee,3 Namkug Kim,3 Joon Beom Seo,3 Yeon-Mok Oh,1 Sang-Do Lee,1 Sei Won Lee1 1Department of Pulmonary and Critical Care Medicine and Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; 2Department of Internal Medicine, College of Medicine, Kangwon National University, Chuncheon, Korea; 3Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Purpose: Endobronchial valve (EBV therapy is increasingly being seen as a therapeutic option for advanced emphysema, but its clinical utility in Asian populations, who may have different phenotypes to other ethnic populations, has not been assessed.Patients and methods: This prospective open-label single-arm clinical trial examined the clinical efficacy and the safety of EBV in 43 consecutive patients (mean age 68.4±7.5, forced expiratory volume in 1 second [FEV1] 24.5%±10.7% predicted, residual volume 208.7%±47.9% predicted with severe emphysema with complete fissure and no collateral ventilation in a tertiary referral hospital in Korea.Results: Compared to baseline, the patients exhibited significant improvements 6 months after EBV therapy in terms of FEV1 (from 0.68±0.26 L to 0.92±0.40 L; P<0.001, 6-minute walk distance (from 233.5±114.8 m to 299.6±87.5 m; P=0.012, modified Medical Research Council dyspnea scale (from 3.7±0.6 to 2.4±1.2; P<0.001, and St George’s Respiratory Questionnaire (from 65.59±13.07 to 53.76±11.40; P=0.028. Nine patients (20.9% had a tuberculosis scar, but these scars did not affect target lobe volume reduction or pneumothorax frequency. Thirteen patients had adverse events, ten (23.3% developed pneumothorax, which included one death due to tension pneumothorax.Conclusion: EBV therapy was as effective and safe in Korean

Forecasting selected specific age mortality rate of Malaysia by using Lee-Carter model

Science.gov (United States)

Shukri Kamaruddin, Halim; Ismail, Noriszura

2018-03-01

Observing mortality pattern and trend is an important subject for any country to maintain a good social-economy in the next projection years. The declining in mortality trend gives a good impression of what a government has done towards macro citizen in one nation. Selecting a particular mortality model can be a tricky based on the approached method adapting. Lee-Carter model is adapted because of its simplicity and reliability of the outcome results with approach of regression. Implementation of Lee-Carter in finding a fitted model and hence its projection has been used worldwide in most of mortality research in developed countries. This paper studies the mortality pattern of Malaysia in the past by using original model of Lee-Carter (1992) and hence its cross-sectional observation for a single age. The data is indexed by age of death and year of death from 1984 to 2012, in which are supplied by Department of Statistics Malaysia. The results are modelled by using RStudio and the keen analysis will focus on the trend and projection of mortality rate and age specific mortality rate in the future. This paper can be extended to different variants extensions of Lee-Carter or any stochastic mortality tool by using Malaysia mortality experience as a centre of the main issue.

Relation between the Lee-Wick and Nambu-Jona-Lasinio models of chiral symmetry breaking

International Nuclear Information System (INIS)

Klevansky, S.P.; Lemmer, R.H.

1990-01-01

The connection between the sigma model of Lee and Wick and the Nambu-Jona-Lasinio (NJL) model is discussed. It is shown that the sigma field potential of the linear Lee-Wick model is identical in form with the variation of the vacuum energy of the NJL system with the baryonic scalar density n s . The sigma field is proportional to n s . Furthermore, the coupling constant and mass of this σ field are fully determined by the NJL model version of the Goldberger-Treiman relation. It is shown further that the restoration of chiral symmetry with increasing baryonic density always occurs via a second order transition in the NJL model, while it is necessarily of first order in the associated linear Lee-Wick model. (orig.)

Persistence of the longnose darter (P. nasuta) in Lee Creek, Oklahoma

Science.gov (United States)

Gatlin, Michael R.; Long, James M.

2011-01-01

The longnose darter Percina nasuta (Bailey) is one of Oklahoma’s rarest fish species (1) and is listed by the state as endangered. Throughout the rest of its range, which includes Missouri, Arkansas and the far eastern portion of Oklahoma, the longnose darter is classified as “rare” or “threatened” (2, 3, 4, 5, 6, 1). This species inhabits both slow- and fast-water habitats with cobble and gravel substrates in medium to large streams (7, 8, 1). Oklahoma populations of longnose darter are known to occur only in the Poteau River and Lee Creek drainages in Le Flore and Sequoyah counties, respectively (9, 10). Cross and Moore (9) collected longnose darters from the Poteau River in 1947. The species was not collected in a subsequent survey of the Poteau River in 1974 (11), possibly because of the effects from the Wister Dam, which was completed in 1949. Darters are especially susceptible to flow alterations from dams (2, 12). This, together with the 1992 completion of Lee Creek Reservoir in Arkansas, has raised concern for the Lee Creek population of longnose darters (13).

Physicochemical aspects of decomposition of silica-alumina ores of argillites and green clays of Chashma-Sang Deposit of the Republic of Tajikistan by hydrochloric and nitric acids

International Nuclear Information System (INIS)

Kayumov, A.M.

2018-01-01

The purpose of work is to study the processes of decomposition of silica-alumina ores of argillites and green clays of Chashma-Sang Deposit of the Republic of Tajikistan by hydrochloric and nitric acids in temperature interval 20-98 deg C with the using of methods of selective extraction of valuable materials; elaboration of rational conditions of decomposition of raw material. Physicochemical properties of initial aluminium comprising ores, intermediate and final products of processing of argillites and green clays have been studied. Kinetic parameters of processes at acidic decomposition of argillites and green clays have been studied as well. The kinetic parameters of processes of decomposition of green clays and argillites by nitric and hydrochloric acids have been calculated. The flowsheet of complex processing of green clays and argillites of Chashma-Sang Deposit has been elaborated.

W3C head Berners-Lee to be knighted

CERN Multimedia

Gross, G

2004-01-01

"Tim Berners-Lee, credited with inventing the World Wide Web and now director of the World Wide Web Consortium, will be named a knight commander, Order of the British Empire, by Queen Elizabeth II, the W3C announced Wednesday" (1 page)

T.D Lee and Lisa Randall visit ATLAS

CERN Multimedia

Pauline Gagnon

Professor Tsung-Dao Lee, who received the Nobel Prize for Physics in 1957 for postulating that parity is not conserved in weak interactions, visited the ATLAS detector this month. He is seen here in the company of Peter Jenni, spokesperson for ATLAS. T.D. Lee is still very active at over 80, pursuing his theory work to this day. Professor Lisa Randall from Harvard University, the well-known theorist behind the Randall-Sundrum theory for extra dimensions, was also part of the group visiting the ATLAS detector. She is seen here with Fabiola Gianotti, deputy spokesperson for ATLAS. Lisa Randall's two initial papers have been quoted both more than 2500 times, making her the most cited theoretical physicist in the world in the last five years as of last autumn - a total of about 10,000 citations! One wonders here if Peter is pointing to a CP-violating graviton spotted in the ATLAS cavern... From left to right: Fabiola Gianotti, Gustaaf Brooijmans, convener of the ATLAS Exotics physics gro...

Yang-Lee zeros for a Potts model of helix-coil transition with nontrivial topology

International Nuclear Information System (INIS)

Ananikian, N.; Ananikyan, L.; Artuso, R.; Sargsyan, K.

2007-07-01

The Yang-Lee partition function zeros of the Q-state Potts model on a zigzag ladder are studied by a transfer-matrix approach. This Q-state model has a non-trivial topology induced by three-site interactions on a zigzag ladder and is proposed as a description of helix-coil transition in homo-polymers. The Yang-Lee zeros are associated to complex values of the solvent-related coupling constant K (magnetic field) and they are exactly derived for arbitrary values of the system parameters: Q, J (coupling constant of hydrogen binding) and temperature. It is shown that there is only a quasi-phase transition for all temperatures. The densities of the Yang-Lee zeros are singular at the edge singularity points and the critical exponent σ = -1/2. (author)

The Balancer Policy Reviewed from the Perspective of the ROK-U.S. Alliance: Toward a Mature ROK-U.S. Alliance

Science.gov (United States)

2006-12-01

one of Korea’s ancient three kingdoms, existed for 700 years ruled by 26 wise kings ) in the papers of the Northeast Project, a government-funded...Relations,” in Korea-U.S. Relations in Transition, ed. Baek Jong-chun and Lee Sang-hyun (Sungnam: Sejong Institute, 2002). 51 military alliance it was...President, President’s Roh’s Inauguration Announcement, Vol. 1, Secretary Office, 2003. 62 Sejong Laboratory, National strategy for 21st century

What Lee Raymond actually said in Beijing [15th WPC

International Nuclear Information System (INIS)

Raymond, Lee.

1997-01-01

When Lee Raymond, Chairman and Chief Executive Officer, Exxon Corporation gave this keynote address at the recent World Petroleum Congress in Beijing, he drew attention to the way economic growth alleviates poverty and to the close linkage between economic growth and energy use. He also drew attention to the weakness of the scientific evidence for climate change being caused by fossil fuel burning and his doubts about the wisdom of setting targets for the reduction of CO 2 emissions. At a press conference after the presentation Lee Raymond assented to the suggestion that the European oil companies have been hijacked by the environmentalists. Petroleum Review has reproduced the full text of the speech so that readers can judge for themselves the merits of the arguments and their likely impact on the Kyoto conference. (UK)

Lee waves: Benign and malignant

Science.gov (United States)

Wurtele, M. G.; Datta, A.; Sharman, R. D.

1993-01-01

The flow of an incompressible fluid over an obstacle will produce an oscillation in which buoyancy is the restoring force, called a gravity wave. For disturbances of this scale, the atmosphere may be treated as dynamically incompressible, even though there exists a mean static upward density gradient. Even in the linear approximation - i.e., for small disturbances - this model explains a great many of the flow phenomena observed in the lee of mountains. However, nonlinearities do arise importantly, in three ways: (1) through amplification due to the decrease of mean density with height; (2) through the large (scaled) size of the obstacle, such as a mountain range; and (3) from dynamically singular levels in the fluid field. These effects produce a complicated array of phenomena - large departure of the streamlines from their equilibrium levels, high winds, generation of small scales, turbulence, etc. - that present hazards to aircraft and to lee surface areas. The nonlinear disturbances also interact with the larger-scale flow in such a manner as to impact global weather forecasts and the climatological momentum balance. If there is no dynamic barrier, these waves can penetrate vertically into the middle atmosphere (30-100 km), where recent observations show them to be of a length scale that must involve the coriolis force in any modeling. At these altitudes, the amplitude of the waves is very large, and the phenomena associated with these wave dynamics are being studied with a view to their potential impact on high performance aircraft, including the projected National Aerospace Plane (NASP). The presentation shows the results of analysis and of state-of-the-art numerical simulations, validated where possible by observational data, and illustrated with photographs from nature.

Polyphenols from Wine Lees as a Novel Functional Bioactive Compound in the Protection Against Oxidative Stress and Hyperlipidaemia

Directory of Open Access Journals (Sweden)

Irena Landeka Jurčević

2017-01-01

Full Text Available The study examines the potential of wine industry by-product, the lees, as a rich mixture of natural polyphenols, and its physiological potential to reduce postprandial metabolic and oxidative stress caused by a cholesterol-rich diet in in vivo model. Chemical analysis of wine lees showed that their total solid content was 94.2 %. Wine lees contained total phenols, total nonflavonoids and total flavonoids expressed in mg of gallic acid equivalents per 100 g of dry mass: 2316.6±37.9, 1332.5±51.1 and 984.1±28.2, respectively. The content of total anthocyanins expressed in mg of cyanidin-3-glucoside equivalents per 100 g of dry mass was 383.1±21.6. Antioxidant capacity of wine lees determined by the DPPH and FRAP methods and expressed in mM of Trolox equivalents per 100 g was 259.8±1.8 and 45.7±1.05, respectively. The experiment lasted 60 days using C57BL/6 mice divided in four groups: group 1 was fed normal diet and used as control, group 2 was fed normal diet with added wine lees, group 3 was fed high-cholesterol diet (HCD, i.e. normal diet with the addition of sunflower oil, and group 4 was fed HCD with wine lees. HCD increased serum total cholesterol (TC by 2.3-fold, triacylglycerol (TAG by 1.5-fold, low-density lipoprotein (LDL by 3.5-fold and liver malondialdehyde (MDA by 50 %, and reduced liver superoxide dismutase (SOD by 50 %, catalase (CAT by 30 % and glutathione (GSH by 17.5 % compared to control. Conversely, treatment with HCD and wine lees reduced TC and LDL up to 1.4 times more than with HCD only, with depletion of lipid peroxidation (MDA and restoration of SOD and CAT activities in liver, approximating values of the control. HDL levels were unaffected in any group. Serum transaminase activity showed no hepatotoxic properties in the treatment with lees alone. In the proposed model, wine lees as a rich polyphenol source could be a basis for functional food products without alcohol.

Dynamical fragmentation of flux tubes in the Friedberg-Lee model

International Nuclear Information System (INIS)

Loh, S.; Greiner, C.; Mosel, U.; Thoma, M.H.

1997-01-01

We present two novel dynamical features of flux tubes in the Friedberg-Lee model. First the fusion of two (anti-)parallel flux tubes, where we extract a string-string interaction potential which has a qualitative similarity to the nucleon-nucleon potential in the Friedberg-Lee model obtained by Koepf et al. Furthermore we show the dynamical breakup of flux tubes via qq-particle production and the disintegration into mesons. We find, as a shortcoming of the present realization of the model, that the full dynamical transport approach presented in a previous publication fails to provide the disintegration mechanism in the semiclassical limit. Therefore, in addition, we present here a molecular dynamical approach for the motion of the quarks and show, as a first application, the space-time development of the quarks and their mean-fields for Lund-type string fragmentation processes. (orig.)

Intermittency and dynamical Lee-Yang zeros of open quantum systems.

Science.gov (United States)

Hickey, James M; Flindt, Christian; Garrahan, Juan P

2014-12-01

We use high-order cumulants to investigate the Lee-Yang zeros of generating functions of dynamical observables in open quantum systems. At long times the generating functions take on a large-deviation form with singularities of the associated cumulant generating functions-or dynamical free energies-signifying phase transitions in the ensemble of dynamical trajectories. We consider a driven three-level system as well as the dissipative Ising model. Both systems exhibit dynamical intermittency in the statistics of quantum jumps. From the short-time behavior of the dynamical Lee-Yang zeros, we identify critical values of the counting field which we attribute to the observed intermittency and dynamical phase coexistence. Furthermore, for the dissipative Ising model we construct a trajectory phase diagram and estimate the value of the transverse field where the stationary state changes from being ferromagnetic (inactive) to paramagnetic (active).

Tim Berners-Lee, World Wide Web inventor

CERN Multimedia

1994-01-01

Former physicist, Tim Berners-Lee invented the World Wide Web as an essential tool for high energy physics at CERN from 1989 to 1994. Together with a small team he conceived HTML, http, URLs, and put up the first server and the first 'what you see is what you get' browser and html editor. Tim is now Director of the Web Consortium W3C, the International Web standards body based at INRIA, MIT and Keio University.

Development of a quantitative food frequency questionnaire for use among the Yup'ik people of Western Alaska.

Science.gov (United States)

Kolahdooz, Fariba; Simeon, Desiree; Ferguson, Gary; Sharma, Sangita

2014-01-01

Alaska Native populations are experiencing a nutrition transition and a resulting decrease in diet quality. The present study aimed to develop a quantitative food frequency questionnaire to assess the diet of the Yup'ik people of Western Alaska. A cross-sectional survey was conducted using 24-hour recalls and the information collected served as a basis for developing a quantitative food frequency questionnaire. A total of 177 males and females, aged 13-88, in six western Alaska communities, completed up to three 24-hour recalls as part of the Alaska Native Dietary and Subsistence Food Assessment Project. The frequency of the foods reported in the 24-hour recalls was tabulated and used to create a draft quantitative food frequency questionnaire, which was pilot tested and finalized with input from community members. Store-bought foods high in fat and sugar were reported more frequently than traditional foods. Seven of the top 26 foods most frequently reported were traditional foods. A 150-item quantitative food frequency questionnaire was developed that included 14 breads and crackers; 3 cereals; 11 dairy products; 69 meats, poultry and fish; 13 fruit; 22 vegetables; 9 desserts and snacks; and 9 beverages. The quantitative food frequency questionnaire contains 39 traditional food items. This quantitative food frequency questionnaire can be used to assess the unique diet of the Alaska Native people of Western Alaska. This tool will allow for monitoring of dietary changes over time as well as the identification of foods and nutrients that could be promoted in a nutrition intervention program intended to reduce chronic disease.

Development of a quantitative food frequency questionnaire for use among the Yup'ik people of Western Alaska.

Directory of Open Access Journals (Sweden)

Fariba Kolahdooz

Full Text Available Alaska Native populations are experiencing a nutrition transition and a resulting decrease in diet quality. The present study aimed to develop a quantitative food frequency questionnaire to assess the diet of the Yup'ik people of Western Alaska. A cross-sectional survey was conducted using 24-hour recalls and the information collected served as a basis for developing a quantitative food frequency questionnaire. A total of 177 males and females, aged 13-88, in six western Alaska communities, completed up to three 24-hour recalls as part of the Alaska Native Dietary and Subsistence Food Assessment Project. The frequency of the foods reported in the 24-hour recalls was tabulated and used to create a draft quantitative food frequency questionnaire, which was pilot tested and finalized with input from community members. Store-bought foods high in fat and sugar were reported more frequently than traditional foods. Seven of the top 26 foods most frequently reported were traditional foods. A 150-item quantitative food frequency questionnaire was developed that included 14 breads and crackers; 3 cereals; 11 dairy products; 69 meats, poultry and fish; 13 fruit; 22 vegetables; 9 desserts and snacks; and 9 beverages. The quantitative food frequency questionnaire contains 39 traditional food items. This quantitative food frequency questionnaire can be used to assess the unique diet of the Alaska Native people of Western Alaska. This tool will allow for monitoring of dietary changes over time as well as the identification of foods and nutrients that could be promoted in a nutrition intervention program intended to reduce chronic disease.

A Study on the Armillary Spheres of the Confucianists in Joseon Dynasty

Science.gov (United States)

Lee, Yong Sam; Kim, Sang Hyuk; Lee, Min Soo; Jeong, Jang Hae

2010-12-01

Armillary sphere, generally known as, not only astronomical instrument for observing astronomical phenomena but also symbolizes the royal authority and royal political ideology which is based on Confucianism. Among the well-reputed Confucian scholars were built their own armillary spheres. However, these armillary spheres which exist are damaged and most of parts of its have been lost. We analyzed and measured the remnants of armillary spheres which were made by Toegye Lee Hwang, Uam Song Si-Yeol and Goedam Bae Sang-Yeol who were well-reputed Confucian scholars in Joseon Dynasty, and have been executed the restorations of Toegye Lee Hwang and Song Si-Yeols armillary sphere based on the drawings which were drawn as the original form by analysis and measurement of its remnants.

Fundamental solution of bond pricing in the Ho-Lee stochastic interest rate model under the invariant criteria

Directory of Open Access Journals (Sweden)

Burhaneddin İzgi

2017-03-01

under the invariant criteria. We obtain transformations between Ho-Lee model with the corresponding linear (1 + 1 partial differential equation and the first Lie canonical form which is identical to the classical heat equation. These transformations help us to generate the fundamental solution for the Ho-Lee model with respect to the fundamental solution of the classical heat equation sense. Moreover, as a financial application of the Ho-Lee model, we choose the drift term from power functions and perform simulations via Milstein method. Furthermore, we obtain important results for the parameter calibration of the corresponding drift term by using the simulation results.

Duke Power's William Lee says INPO's purpose is solving industry problems, not educating the public

International Nuclear Information System (INIS)

Anon.

1984-01-01

Former Institute of Nuclear Power Operations (INPO) head, William Lee thinks that nuclear critics could misuse institute reports on investigations of nuclear plant construction and operation. If so, that would outweigh any public relations benefits of using the reports to inform and educate the public. Lee thinks the best way to gain public confidence is for the industry to perform well. The four-year-old institute was originally formed to improve operations, but recent problems with unfinished plants led to a system of construction audits. By offering guidance to companies building nuclear plants, INPO is meeting competition from utilities such as Duke Power, which is now marketing its expertise in designing and building plants. Lee emphasizes the importance of asking the right questions that will lead to quality control

Deterministic and stochastic trends in the Lee-Carter mortality model

DEFF Research Database (Denmark)

Callot, Laurent; Haldrup, Niels; Kallestrup-Lamb, Malene

2015-01-01

The Lee and Carter (1992) model assumes that the deterministic and stochastic time series dynamics load with identical weights when describing the development of age-specific mortality rates. Effectively this means that the main characteristics of the model simplify to a random walk model with age...... mortality data. We find empirical evidence that this feature of the Lee–Carter model overly restricts the system dynamics and we suggest to separate the deterministic and stochastic time series components at the benefit of improved fit and forecasting performance. In fact, we find that the classical Lee......–Carter model will otherwise overestimate the reduction of mortality for the younger age groups and will underestimate the reduction of mortality for the older age groups. In practice, our recommendation means that the Lee–Carter model instead of a one-factor model should be formulated as a two- (or several...

INCA Modelling of the Lee System: strategies for the reduction of nitrogen loads

Science.gov (United States)

Flynn, N. J.; Paddison, T.; Whitehead, P. G.

The Integrated Nitrogen Catchment model (INCA) was applied successfully to simulate nitrogen concentrations in the River Lee, a northern tributary of the River Thames for 1995-1999. Leaching from urban and agricultural areas was found to control nitrogen dynamics in reaches unaffected by effluent discharges and abstractions; the occurrence of minimal flows resulted in an upward trend in nitrate concentration. Sewage treatment works (STW) discharging into the River Lee raised nitrate concentrations substantially, a problem which was compounded by abstractions in the Lower Lee. The average concentration of nitrate (NO3) for the simulation period 1995-96 was 7.87 mg N l-1. Ammonium (NH4) concentrations were simulated less successfully. However, concentrations of ammonium rarely rose to levels which would be of environmental concern. Scenarios were run through INCA to assess strategies for the reduction of nitrate concentrations in the catchment. The conversion of arable land to ungrazed vegetation or to woodland would reduce nitrate concentrations substantially, whilst inclusion of riparian buffer strips would be unsuccessful in reducing nitrate loading. A 50% reduction in nitrate loading from Luton STW would result in a fall of up to 5 mg N l-1 in the reach directly affected (concentrations fell from maxima of 13 to 8 mg N l-1 , nearly a 40 % reduction), whilst a 20% reduction in abstractions would reduce maximum peaks in concentration in the lower Lee by up to 4 mg l-1 (from 17 to 13 mg N l-1, nearly a 25 % reduction),.

A critique of the Lees-Marshment market-oriented party model

DEFF Research Database (Denmark)

Ormrod, Robert P.

2006-01-01

This article presents conceptual and empirical criticisms of the Lees-Marshment market-oriented party model. Conceptual criticisms are the short-term approach, the narrow focus on voters, the nature of the relationship to competitors, a tendency towards centralisation and the lack of a distinction...

Interactions between yeast lees and wine polyphenols during simulation of wine aging: I. Analysis of remnant polyphenolic compounds in the resulting wines.

Science.gov (United States)

Mazauric, Jean-Paul; Salmon, Jean-Michel

2005-07-13

Wine aging on yeast lees is a traditional enological practice used during the manufacture of wines. This technique has increased in popularity in recent years for the aging of red wines. Although wine polyphenols interact with yeast lees to a limited extent, such interactions have a large effect on the reactivity toward oxygen of wine polyphenolic compounds and yeast lees. Various domains of the yeast cell wall are protected by wine polyphenols from the action of extracellular hydrolytic enzymatic activities. Polysaccharides released during autolysis are thought to exert a significant effect on the sensory qualities of wine. We studied the chemical composition of polyphenolic compounds remaining in solution or adsorbed on yeast lees after various contact times during the simulation of wine aging. The analysis of the remnant polyphenols in the wine indicated that wine polyphenols adsorption on yeast lees follows biphasic kinetics. An initial and rapid fixation is followed by a slow, constant, and saturating fixation that reaches its maximum after about 1 week. Only very few monomeric phenolic compounds remained adsorbed on yeast lees, and no preferential adsorption of low or high polymeric size tannins occurred. The remnant condensed tannins in the wine contained fewer epigallocatechin units than the initial tannins, indicating that polar condensed tannins were preferentially adsorbed on yeast lees. Conversely, the efficiency of anthocyanin adsorption on yeast lees was unrelated to its polarity.

Proses Individuasi Carl Gustav Jung pada Tokoh Erika Kohut dalam Novel Sang Guru Piano Karya Elfriede Jelinek

Directory of Open Access Journals (Sweden)

M. Oktavia Vidiyanti

2007-12-01

Full Text Available A personality structure that appears in Erika is similar to one of an important part of Carl Gustav Jung psychology. Jung states that personality is a psiko that covers consciousness and unconsciousness. This psiko will develop to be a stable unity. If every system develops in every individual absolutely, so a health and integrated personality will be achieved. That process in Jung is known as a self­ individualized process. The aim of individualism is a self­achievement. Individual is not only as a psiko centre but also as a representation of the whole individual that unites consciousness and unconsciousness. It is like the character "Erika Kohut" in the novel "Sang Guru Piano".

Outlining the influence of non-conventional yeasts in wine ageing over lees.

Science.gov (United States)

Belda, Ignacio; Navascués, Eva; Marquina, Domingo; Santos, Antonio; Calderón, Fernando; Benito, Santiago

2016-07-01

During the last decade, the use of innovative yeast cultures of both Saccharomyces cerevisiae and non-Saccharomyces yeasts as alternative tools to manage the winemaking process have turned the oenology industry. Although the contribution of different yeast species to wine quality during fermentation is increasingly understood, information about their role in wine ageing over lees is really scarce. This work aims to analyse the incidence of three non-Saccharomyces yeast species of oenological interest (Torulaspora delbrueckii, Lachancea thermotolerans and Metschnikowia pulcherrima) and of a commercial mannoprotein-overproducer S. cerevisiae strain compared with a conventional industrial yeast strain during wine ageing over lees. To evaluate their incidence in mouthfeel properties of wine after 4 months of ageing, the mannoprotein content of wines was evaluated, together with other wine analytic parameters, such as colour and aroma, biogenic amines and amino acids profile. Some differences among the studied parameters were observed during the study, especially regarding the mannoprotein concentration of wines. Our results suggest that the use of T. delbrueckii lees in wine ageing is a useful tool for the improvement of overall wine quality by notably increasing mannoproteins, reaching values higher than obtained using a S. cerevisiae overproducer strain. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Selective Migration among Southern Blacks: A Reinterpretation of Lee (1951).

Science.gov (United States)

Wolff, JosePh L.

1979-01-01

Explanations of differences in IQs of Northern and Southern Blacks focus on selective migration (hereditarians) or environmental causes such as education, discrimination and cultural deprivation. In this paper the environmentalist position is questioned and certain neglected features of Lee's data are construed as providing strong evidence for…

Lee Miller à travers la Roumanie, l’appareil photo à la main (1946

Directory of Open Access Journals (Sweden)

Adrian-Silvan Ionescu

2012-01-01

Full Text Available A former model and fashion photographer turned war photographer, Lee Miller visited Romania twice, in 1938 and 1946 respectively. After her second visit she published her impressions and pictures, under the title of Roumania, in Vogue magazine. Besides the published material there are her manuscripts from The Lee Miller Achives at Farley Farm House, East Sussex, England, on which this paper is based. She crossed the border coming from Hungary in early February 1946. Heading for Sibiu her car, a Chevrolet Sedan, slipping on the ice-covered road, stopped on a snowbank far off in the ditch. While looking for help in the nearby village she and her companions left the car unguarded to discover it plundered of everything, wheels included.On a Sunday afternoon she had the privilege of being received by King Mihai I and Queen Mother Elena with whom she talked exstensively. She also took magnificent pictures with the Royal Family in the imposing Peleş Castle. At Sinaia, „the summer capital of Roumania” she had also the opportunity to portray Dinu Brătianu and Iuliu Maniu, the two elderly statesmen. Maniu was surrounded by friends and party members, among whom was young Corneliu Coposu, his private secretary.Moving to Bucharest, she met old friends such as Harri Brauner and his wife, Lena Constante, with whom she wandered through the country eight years ago. Lena and Elena Pătrășcanu, wife of Lucrețiu Pătrășcanu, Minister of Justice, have started a successful marionette theatre where Lee took nice pictures. Other were taken on the streets, with peasants, street vendors and their customers. Harri took her to a bistro where they met Maria Lătărețu, the celebrating folk singer whom Brauner recorded many times. They enjoyed her songs. Suffering from fibrositis, Lee Miller undertook a peculiar treatment in a gypsy village where the inhabitants were dancing bears trainers. She was massaged by a bear weighing about 300 pounds while Brauner took

A State-Space Estimation of the Lee-Carter Mortality Model and Implications for Annuity Pricing

OpenAIRE

Man Chung Fung; Gareth W. Peters; Pavel V. Shevchenko

2015-01-01

In this article we investigate a state-space representation of the Lee-Carter model which is a benchmark stochastic mortality model for forecasting age-specific death rates. Existing relevant literature focuses mainly on mortality forecasting or pricing of longevity derivatives, while the full implications and methods of using the state-space representation of the Lee-Carter model in pricing retirement income products is yet to be examined. The main contribution of this article is twofold. Fi...

Armed Forces Institute of Regenerative Medicine Annual Report 2011

Science.gov (United States)

2012-01-01

using the virus . They have generated high titer viruses for both the decorin and CAR- decorin and produced high yields of decorins devoid of the...involve goats, sheep, dogs, cats , and primates with nerve gaps ranging from 3–90 mm. However, large animal studies are very expensive and take 2–4 years...Leader(s): George Christ, PhD (WFIRM) Project Team Members: James Yoo, MD, PhD, Sang Jin Lee, PhD, Benjamin T. Corona , PhD, and Masood A

A Survey of Cyber Ranges and Testbeds

Science.gov (United States)

2013-10-01

2012. [8] S. W. Neville and K. F. Li , "The Rational for Developing Larger-scale 1000+ Machine Emulation-Based Research Test Beds," WAINA 2009, pp...2002, pp. 6-2671-2676, 6-2678-6- 2682 vol. 6. [20] P. Pederson, D. Lee, G. Shu, D. Chen, Z. Liu, N. Li , and L. Sang, "Virtual Cyber- Security Testing...attacks with applications in homeland defense training." AeroSense 2003. International Society for Optics and Photonics, 2003. [54] Zhou, Mian

A Study on the Armillary Spheres of the Confucianists in Joseon Dynasty

Directory of Open Access Journals (Sweden)

Yong Sam Lee

2010-12-01

Full Text Available Armillary sphere, generally known as, not only astronomical instrument for observing astronomical phenomena but also symbolizes the royal authority and royal political ideology which is based on Confucianism. Among the well-reputed Confucian scholars were built their own armillary spheres. However, these armillary spheres which exist are damaged and most of parts of its have been lost. We analyzed and measured the remnants of armillary spheres which were made by Toegye Lee Hwang, Uam Song Si-Yeol and Goedam Bae Sang-Yeol who were well-reputed Confucian scholars in Joseon Dynasty, and have been executed the restorations of Toegye Lee Hwang and Song Si-Yeols armillary sphere based on the drawings which were drawn as the original form by analysis and measurement of its remnants.

Brassia campestris L. ssp. chinensis L.var. utilis Tsen et Lee

African Journals Online (AJOL)

omodibo

2012-12-31

Dec 31, 2012 ... On the basis of morphological and cultural features, the pathogen ... Alternaria isolate from Purple-Caitai showed 99% identity with other ITS sequences of .... Cho KH, Park SH, Kim KT, Kim S, Kim JS, Park BS, Woo JG, Lee HJ.

Numerical Simulation of a Lee Wave Case over Three-Dimensional Mountainous Terrain under Strong Wind Condition

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Lei Li

2013-01-01

Full Text Available This study of a lee wave event over three-dimensional (3D mountainous terrain in Lantau Island, Hong Kong, using a simulation combining mesoscale model and computational fluid dynamics (CFD model has shown that (1 3D steep mountainous terrain can trigger small scale lee waves under strong wind condition, and the horizontal extent of the wave structure is in a dimension of few kilometers and corresponds to the dimension of the horizontal cross-section of the mountain; (2 the life cycle of the lee wave is short, and the wave structures will continuously form roughly in the same location, then gradually move downstream, and dissipate over time; (3 the lee wave triggered by the mountainous terrain in this case can be categorized into “nonsymmetric vortex shedding” or “turbulent wake,” as defined before based on water tank experiments; (4 the magnitude of the wave is related to strength of wind shear. This study also shows that a simulation combining mesoscale model and CFD can capture complex wave structure in the boundary layer over realistic 3D steep terrain, and have a potential value for operational jobs on air traffic warning, wind energy utilization, and atmospheric environmental assessment.

Markkinointisuunnitelma digitaaliseen markkinointiin Case Baan Lee Beach Resort & Sauna

OpenAIRE

Lähteenmäki, Essi

2017-01-01

Tämän opinnäytetyön tavoitteena on kehittää Baan Lee Beach Resort & Saunan digitaalista markkinointia markkinointisuunnitelman avulla. Yritys on aloittamassa liiketoimintaansa erittäin kilpailulla alalla, jossa digitaalinen markkinointi on tärkeä osa kilpailussa menestymistä ja se on otettava huomioon yrityksen markkinointistrategian tärkeänä osana. Markkinointisuunnitelmalla pyritään takaamaan markkinointistrategian mukainen toiminta. Markkinointisuunnitelmassa kuvataan yrityksen nykyti...

Servicing the first web server - Tim Berners-Lee's NeXT

CERN Multimedia

unknown, Association aBCM

2009-01-01

In August 2009 a team from the Association aBCM in Lausanne came to CERN to give the world's first web server a health check under the watchful eye of web pioneer Robert Cailliau. They took an image of the hard drive at this time, copies of which were given to Robert Cailliau and Tim Berners-Lee.

A relation between deformed superspace and Lee-Wick higher-derivative theories

Science.gov (United States)

Dias, M.; Ferrari, A. F.; Palechor, C. A.; Senise, C. R., Jr.

2015-07-01

We propose a non-anticommutative superspace that relates to the Lee-Wick type of higher-derivative theories, which are known for their interesting properties and have led to proposals of phenomenologically viable higher-derivative extensions of the Standard Model. The deformation of superspace we consider does not preserve supersymmetry or associativity in general, but, we show that a non-anticommutative version of the Wess-Zumino model can be properly defined. In fact, the definition of chiral and antichiral superfields turns out to be simpler in our case than in the well known N=1/2 supersymmetric case. We show that when the theory is truncated at the first nontrivial order in the deformation parameter, supersymmetry is restored, and we end up with a well-known Lee-Wick type of higher-derivative extension of the Wess-Zumino model. Thus, we show how non-anticommutativity could provide an alternative mechanism for generating these higher-derivative theories.

Concentrações sangüíneas de metais pesados e praguicidas organoclorados em crianças de 1 a 10 anos

Directory of Open Access Journals (Sweden)

Santos Filho Eladio

1993-01-01

Full Text Available Foi realizado estudo em 6 bairros do Município de Cubatão, SP, Brasil, situados às margens dos principais rios do município, com uma amostragem de 251 crianças de 1 a 10 anos de idade. Foram verificadas as concentrações sangüíneas de praguicidas organoclorados em 242 crianças, sendo que 73 crianças (30% apresentaram concentrações de p-p'DDE (média = 0,85 ± 2,13 µg/l., e em 47 crianças (19% foi encontrado HCH total (média = 0,28 ± 0,79 µg/l.. Verificou-se também a concentração sangüínea de chumbo e mercúrio, sendo que se obteve a plumbemia média de 17,8 ± 5,8 µg/dl. e concentração média de mercúrio de 9,1 ± 6,4 µg/l. Crianças consumidoras de organismos aquáticos de origem exclusiva dos rios de Cubatão apresentaram teores médios de mercúrio (média = 14,7 ±7,1 µg/l. significativamente maiores (p < 0,04 em comparação às crianças não consumidoras de organismos aquáticos de qualquer origem (média = 10,0 ± 6,5 µg/l..

Forecasting the mortality rates using Lee-Carter model and Heligman-Pollard model

Science.gov (United States)

Ibrahim, R. I.; Ngataman, N.; Abrisam, W. N. A. Wan Mohd

2017-09-01

Improvement in life expectancies has driven further declines in mortality. The sustained reduction in mortality rates and its systematic underestimation has been attracting the significant interest of researchers in recent years because of its potential impact on population size and structure, social security systems, and (from an actuarial perspective) the life insurance and pensions industry worldwide. Among all forecasting methods, the Lee-Carter model has been widely accepted by the actuarial community and Heligman-Pollard model has been widely used by researchers in modelling and forecasting future mortality. Therefore, this paper only focuses on Lee-Carter model and Heligman-Pollard model. The main objective of this paper is to investigate how accurately these two models will perform using Malaysian data. Since these models involves nonlinear equations that are explicitly difficult to solve, the Matrix Laboratory Version 8.0 (MATLAB 8.0) software will be used to estimate the parameters of the models. Autoregressive Integrated Moving Average (ARIMA) procedure is applied to acquire the forecasted parameters for both models as the forecasted mortality rates are obtained by using all the values of forecasted parameters. To investigate the accuracy of the estimation, the forecasted results will be compared against actual data of mortality rates. The results indicate that both models provide better results for male population. However, for the elderly female population, Heligman-Pollard model seems to underestimate to the mortality rates while Lee-Carter model seems to overestimate to the mortality rates.

Optimization Evaluation: Lee Chemical Superfund Site, City Of Liberty, Clay County, Missouri

Science.gov (United States)

The Lee Chemical Superfund Site (site) is located along Missouri Highway 210 in Liberty, Missouri, approximately 15 miles east of Kansas City, Missouri. Currently, the site is a vacant lot of approximately2.5 acres in a flat alluvial plain.

Enzymatic hydrolysis on protein and β-glucan content of Sang-yodrice bran hydrolysatesand their anti-inflammatory activityonRAW 264.7 cells

Directory of Open Access Journals (Sweden)

Natcha Phantuwong

2017-12-01

Full Text Available Background: Research focusing on the improvement of the utilization of rice bran is increasing due to its nutritional properties. Several biological activities of rice bran hydrolysates and its constituents have been reported. Sang-yod rice, a local rice variety in Southern of Thailand, is a pigmented rice. Furthermore, its bran has high nutritive value and health beneficial components. Accordingly, there is growing interest in transforming this by-product into a functional food ingredient. Objective: To investigate the effect of enzymatic hydrolysis processes on the digestion of protein and β-glucan and evaluate anti-proinflammatory properties of selected hydrolysates on RAW 264.7 macrophage cells. Method: Sang-yod rice bran hydrolysates were obtained using a single or co-enzymatic hydrolysis process and sequential hydrolysis process using amyloglucosidase and protease G6. Effects of enzyme concentration (3-5% v/w and hydrolysis duration (30, 60, and 120 min on soluble protein and β-glucan contents of obtained rice bran hydrolysates were evaluated. The selected rice bran hydrolysates were evaluated for their cell viability and inhibition against NO and pro-inflammatory cytokines generation on RAW 264.7 mouse macrophage cell lines. Results: Protein content (0.59-3.37 % of the rice bran hydrolysates (RBHs was increased by increasing of enzyme concentration (3-5% v/w and hydrolysis time (60-120 min. However, the β-glucan content (0.88-4.63% of RBHs decreased with the increase of those parameters. The RBHs derived by the sequential process using 5% v/w enzyme concentration and 60 min hydrolysis time gave high protein (3.23% and high β-glucan (4.02% contents. The hydrolysates with high amount of protein and/or β-glucan contents demonstrated no cytotoxicity against RAW 264.7 cells at concentration range of 100-2,000 μg/ml. Additionally, they demonstrated NO inhibition and pro-inflammatory inhibition ranges of 49.09-71.63% and 9

Seismic test of a full scale model of five-story stone Pagoda of Sang-Gye-Sa

International Nuclear Information System (INIS)

Kim, J. K.; Park, C. U.; Jung, C. K.; Ryu, H.; Fujita, Kaori

1999-01-01

There occurred a moderate size earthquake of M=5 at Whagae-Myun, Hadong-Gun, Kyongsangnam-Do of Korea. It caused severe damage to the buildings and other structures in Sang-Gye-Sa, a famous and beautiful Buddhist Temple. The 5-story stone pagoda was standing in front of Keumdang. The top component tipped over and fell to the ground during the earthquake. In order to have accurate and quantitative estimate of the intensity of earthquake, a full-scale replica is made through rigorous verification process. The completed model was mounted on the shaking table and subjected to the seismic tests. It was observed that the top component overturned at 0.16 G of EPGA when the NS component of the 1940 El Centro earthquake records was used as the input motion. A brief history of this project is presented and important test results are reported and their implication is discussed

Komisjon plaanib ökotoodete eelistamist liidu hangetel / Merike Lees

Index Scriptorium Estoniae

Lees, Merike, 1976-

2004-01-01

Euroopa Komisjon kavatseb luua reeglid, mis annavad hangetel eelise lisaks keskkonnajuhtimisstandardeid rakendanud ettevõtetele ka ühenduse ökomärgist omavatele toodetele. Ettevõtete juhtide kommentaarid ökomärgise kasutamise kohta. Lisad: Ökotoode peab vastama ligi paarikümnele kriteeriumile; Ökomärgise litsentsi eeltöö tehakse Eestis. Vt. samas: Ökomärgise litsentsi väljastav pädev asutus tuleb Eestisse. Kommenteerivad Merike Lees ja Anu-Maaja Pallok

Tentative identification of polar and mid-polar compounds in extracts from wine lees by liquid chromatography-tandem mass spectrometry in high-resolution mode.

Science.gov (United States)

Delgado de la Torre, M P; Priego-Capote, F; Luque de Castro, M D

2015-06-01

Sustainable agriculture has a pending goal in the revalorization of agrofood residues. Wine lees are an abundant residue in the oenological industry. This residue, so far, has been used to obtain tartaric acid or pigments but not for being qualitatively characterized as a source of polar and mid-polar compounds such as flavonoids, phenols and essential amino acids. Lees extracts from 11 Spanish wineries have been analyzed by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) in high resolution mode. The high-resolution power of LC-MS/MS has led to the tentative identification of the most representative compounds present in wine lees, comprising primary amino acids, anthocyans, flavanols, flavonols, flavones and non-flavonoid phenolic compounds, among others. Attending to the profile and content of polar and mid-polar compounds in wine lees, this study underlines the potential of wine lees as an exploitable source to isolate interesting compounds. Copyright © 2015 John Wiley & Sons, Ltd.

Time for a new language for asthma control: results from REALISE Asia

OpenAIRE

Price, David; David-Wang, Aileen; Cho, Sang-Heon; Ho, James Chung-Man; Jeong, Jae-Won; Liam, Chong-Kin; Lin, Jiangtao; Muttalif, Abdul Razak; Perng, Diahn-Warng; Tan, Tze-Lee; Yunus, Faisal; Neira, Glenn

2015-01-01

David Price,1,2 Aileen David-Wang,3 Sang-Heon Cho,4 James Chung-Man Ho,5 Jae-Won Jeong,6 Chong-Kin Liam,7 Jiangtao Lin,8 Abdul Razak Muttalif,9 Diahn-Warng Perng,10,11 Tze-Lee Tan,12 Faisal Yunus,13 Glenn Neira14 On behalf of the REcognise Asthma and LInk to Symptoms and Experience (REALISE) Asia Working Group 1Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK; 2Research in Real Life, Singapore; 3University of the Philippines-Philippine General Hospital, Manila, Philippine...

Symposium on Molecular Spectroscopy (40th) Held at Columbus, Ohio on 17-21 June 1985.

Science.gov (United States)

1985-06-21

INFRARED-MICROWAVE SIDEBAND LASER SPECTROSCOPY OF THE v, AND 2v,*v, BANDS OF 1𔃽CHF’ SANG LEE, R. H. SCHWENDEMAN, AND GOTTFRIED MAGERL Approximately...University, Mississippi State, Mississippi 39762 FA6. (9:4 FORCE CONSTANTS FOR THE CYCLOPROPENYL CATION NORMAN C. CRAIG, JULIANTO PRANATA, SARA JAMIE...WHJO RA14 MAESSEN, B.--RFl4, RF15 HEAVEN, M. C. --MG7, MG8, MG9, KENNY,’ J. E.--MF9, M[FlO, M_7l1 MAGERL, GOTTFRIED --RF5 Presiding over Session MG

HISTORY EDUCATION - SOME THOUGHTS FROM THE UK: interviews Peter J. Lee

Directory of Open Access Journals (Sweden)

Cristiani Bereta da Silva

2014-05-01

Peter Lee was, until he very recently retired, a senior lecturer in the History Education Unit at the Institute of Education at the University of London. Having taught History in primary and secondary schools, Professor Lee has coordinated several research projects related to History Teaching and Learning, including CHATA (Concepts of History and Teaching Approaches a project well-known in Brazil. Several of his publications investigate the ideas that children and teenagers have over History in several books, chapters, and articles – many of these with Rosalyn Ashby as co-author.  Some of his articles have been translated to Portuguese, circulating among researchers concerned with understanding how children learn History. The questions in this interview have been elaborated so that Peter Lee’s reflections may collaborate with the development of History Teaching and History Education research in Brazil. All contact has been made via e-mail, a rather useful tool that has shortened the distance between Florianópolis and London for a few long moments between July and October 2012.

' "Life is Movement": Vernon Lee and Sculpture'

DEFF Research Database (Denmark)

Østermark-Johansen, Lene

2018-01-01

How do living, breathing human bodies respond to the inert bodies of sculpture? This article examines some of the art-theoretical and psychological writings of Violet Paget (‘Vernon Lee’) and Clementina Anstruther-Thomson of the 1880s and 1890s in an attempt to map the evolution of their formalist...... art criticism. Engaging with the eighteenth-century ghosts of Johann Joachim Winckelmann and Gotthold Ephraim Lessing, Lee and Anstruther-Thomson created their very own exploration of art forms evolving in space and in time. Questioning how our reading of literature affects our reading of sculpture...... from Lee’s early essays in Belcaro: Being Essays on Sundry Aesthetical Questions (1881) to the late collaborative volume Art and Man (1924)....

Associations between diet and cardiometabolic risk among Yup'ik Alaska Native people using food frequency questionnaire dietary patterns.

Science.gov (United States)

Ryman, T K; Boyer, B B; Hopkins, S; Philip, J; Beresford, S A A; Thompson, B; Heagerty, P J; Pomeroy, J J; Thummel, K E; Austin, M A

2015-12-01

In previous analyses, we identified three dietary patterns from food frequency questionnaire data among a sample of Yup'ik Alaska Native people living in Southwest Alaska: a "subsistence foods" dietary pattern and two market-based dietary patterns "processed foods" and "fruits and vegetables". In this analysis, we aimed to characterize the association between the dietary patterns and cardiometabolic (CM) risk factors (lipids, blood pressure, glucose, adiposity). We used multilevel linear regression to estimate the mean of each CM risk factor, comparing participants in the 4th to the 1st quartile of each dietary pattern (n = 637). Models were adjusted for age, sex, past smoking, current smoking, and physical activity. Mean log triglyceride levels were significantly higher among participants in the 4th compared to the 1st quartile of the processed foods dietary pattern (β = 0.11). Mean HbA1c percent was significantly lower (β = -0.08) and mean diastolic blood pressure (DBP) mm Hg was significantly higher (β = 2.87) among participants in the 4th compared to the 1st quartile of the fruits and vegetables dietary pattern. Finally, mean log triglyceride levels and mean DBP mm Hg were significantly lower among participants in the 4th compared to the 1st quartile of the subsistence foods dietary pattern (β = -0.10 and β = -3.99 respectively). We found increased CM risk, as reflected by increased triglycerides, associated with eating a greater frequency of processed foods, and reduced CM risk, as reflected by lower triglycerides and DBP, associated with eating a greater frequency of subsistence foods. Copyright © 2015 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Looking for Asian butch-dykes: exploring filmic representations of East Asian butch-dykes in Donna Lee's Enter the Mullet.

Science.gov (United States)

Lin, Hui-Ling

2009-01-01

Asian butch-dykes have been overlooked in analyses of Chinese cinema, studies that often concentrate on "feminized" transgender roles. This article examines cinematic representations of Asian butch-dykes through film analysis of Enter the Mullet (2004), a five-minute short, and in-depth interviews with the filmmaker, Donna Lee, a Chinese-Canadian in Vancouver. Lee's film is inspired by Enter the Dragon (1973), starring Bruce Lee, the most recognized icon of Asian masculinity. Combining with the mullet hairstyle, which is often associated with White working-class, the filmmaker introduces viewers to the hybrid masculinity of Asian butch-dykes. The article argues that Asian female masculinity can be a strategic means of destabilizing the hegemony of White-male-middle-class masculinity.

Vertical structure and microphysical characteristics of precipitation on the high terrain and lee side of the Olympic Mountains

Science.gov (United States)

Zagrodnik, J. P.; McMurdie, L. A.; Houze, R.

2017-12-01

As mid-latitude cyclones pass over coastal mountain ranges, the processes producing their clouds and precipitation are modified when they encounter complex terrain, leading to a maximum in precipitation fallout on the windward slopes and a minimum on the lee side. The precipitation that does reach the high terrain and lee side of a mountain range can be theoretically determined by a complex interaction between the dynamics of air lifting over the terrain, the thermodynamics of moist air, and the microphysical time required to grow particles large enough to fall out. To date, there have been few observational studies that have focused on the nonlinear microphysical processes contributing to the variability of precipitation that is received on the lee side slopes of a mountain range such as the Olympic Mountains. The 2015-16 Olympic Mountains Experiment (OLYMPEX) collected unprecedented observations on the high terrain and lee side of the Olympic Mountains including frequent soundings on Vancouver Island, dual-polarization Doppler radar, multi-frequency airborne radar, and ground-based particle size and crystal habit observations at the higher elevation Hurricane Ridge site. We utilize these observations to examine the evolution of the vertical structure and microphysical precipitation characteristics over the high terrain and leeside within the context of large-scale dynamic and thermodynamic conditions that evolve during the passage of cold season mid-latitude cyclones. The primary goal is to determine the degree to which the observed variability in lee side precipitation amount and microphysical properties are controlled by variations in temperature, flow speed and direction, shear, and stability associated with characteristic synoptic storm sectors and frontal passages.

On the Seventh Day, He Rested: Lee Kuan Yew and the Creation of Singapore

National Research Council Canada - National Science Library

Neary, Patrick C

1997-01-01

...-oriented domestic policies in pursuit of national goals. Lee's paternal authoritarianism proved to be highly successful, but this success sowed the seeds of discontent now producing weeds in his island paradise.

Phenolic characterization of aging wine lees: Correlation with antioxidant activities.

Science.gov (United States)

Romero-Díez, R; Rodríguez-Rojo, S; Cocero, M J; Duarte, C M M; Matias, A A; Bronze, M R

2018-09-01

Aging wine lees are water-wastes produced during the wine aging inside wood barrels that can be considered as alternative sources of bioactive compounds. Phenolic characterization and antioxidant activity (AA) measurements of wines lees solid-liquid extracts have been undertaken on a dry extract (DE) basis. Solvents with different polarities (water, methanol, ethanol, two hydroalcoholic mixtures and acetone) were used. Total phenolic (TPC) and total flavonoid contents (TFC) were determined. The mixture of 75:25(v/v) EtOH:H 2 O showed the highest values with 254 mg GAE /g DE and 146 mg CATE /g DE respectively. HORAC, HOSC and FRAP were used to determine the AA of the extracts being also highest for the mixture of 75:25(v/v) EtOH:H 2 O (4690 µmol CAE /g DE , 4527 µmol TE /g DE and 2197 µmol TE /g DE , respectively). For ORAC method, methanol extract showed the best value with 2771 µmol TE /g DE . Correlations between TPC, TFC, phenolic compounds and AA were determined. Most relevant compounds contributing to AA were identified using data from mass spectrometry, being mainly anthocyanins. Copyright © 2018 Elsevier Ltd. All rights reserved.

Lee-side flow structures of very low aspect ratio cruciform wing–body configurations

CSIR Research Space (South Africa)

Tuling, S

2013-12-01

Full Text Available A numerical and experimental investigation was performed to study the dominant flow structures in the lee side of a cruciform wing–body configuration at supersonic speeds in the + orientation. The wings or strakes are of very low aspect ratio...

Näitleja Tommy Lee Jonesi meditatsioon režissööritoolis / Andris Feldmanis

Index Scriptorium Estoniae

Feldmanis, Andris, 1982-

2007-01-01

Vestern "Melquiades Estrada kolm matust" ("The Three Burials of Melquiades Estrada") : stsenarist Guillermo Arriaga : režissöör ja osatäitja Tommy Lee Jones : operaator Chris Menges : Ameerika Ühendriigid, 2005

Comparison of a new digital KM screen test with conventional Hess and Lees screen tests in the mapping of ocular deviations.

Science.gov (United States)

Thorisdottir, Rannveig Linda; Sundgren, Johanna; Sheikh, Rafi; Blohmé, Jonas; Hammar, Björn; Kjellström, Sten; Malmsjö, Malin

2018-05-28

To evaluate the digital KM screen computerized ocular motility test and to compare it with conventional nondigital techniques using the Hess and Lees screens. Patients with known ocular deviations and a visual acuity of at least 20/100 underwent testing using the digital KM screen and the Hess and Lees screen tests. The examination duration, the subjectively perceived difficulty, and the patient's method of choice were compared for the three tests. The accuracy of test results was compared using Bland-Altman plots between testing methods. A total of 19 patients were included. Examination with the digital KM screen test was less time-consuming than tests with the Hess and Lees screens (P digital KM screen). Patients found the test with the digital KM screen easier to perform than the Lees screen test (P = 0.009) but of similar difficulty to the Hess screen test (P = 0.203). The majority of the patients (83%) preferred the digital KM screen test to both of the other screen methods (P = 0.008). Bland-Altman plots showed that the results obtained with all three tests were similar. The digital KM screen is accurate and time saving and provides similar results to Lees and Hess screen testing. It also has the advantage of a digital data analysis and registration. Copyright © 2018 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.

Blood constituents of holstein cows fed with corn or elephant-grass silages / Constituintes sangüíneos de vacas da raça holandesa alimentadas com silagens de milho ou de capim-elefante

Directory of Open Access Journals (Sweden)

Valter Harry Bumbieris Júnior

2010-07-01

Full Text Available The objective of this work was to evaluate the effects of corn (Zea mays L. silage and elephant-grass (Pennisetum purpureum Schum silage on the nutrition of cows during lactation, over some of the blood constituents (glucose, triglycerides and urea. The treatments were three silages (corn silage, elephant-grass silage with bacterial inoculating, elephant-grass silage with enzyme-bacterial inoculating. Nine Holstein cows, with a medium weight of 520 kg, were distributed in experimental delineation of simultaneous triple Latin square. The blood glucose rates were considered normal, independents of the silage used. Concerning the triglicerides levels, it was verified that they are below normal to the different silages. One of the reasons would be the low fat level on the diet. The blood levels of urea observed on the three treatments are considered normal. There was not significant difference among the different kinds of silage in relation to the blood levels of urea, glucose and triglycerides.O objetivo deste trabalho foi avaliar os efeitos do fornecimento de silagem de milho (Zea mays L. e silagem de capim-elefante (Pennisetum purpureum Schum na alimentação de vacas em lactação, sobre alguns dos constituintes sangüíneos (glicose, triglicerídeos e uréia. Os tratamentos foram três silagens (silagem de milho, silagem de capim-elefante com inoculante bacteriano, silagem de capim-elefante com inoculante enzimo-bacteriano. Foram utilizadas nove vacas da raça holandesa, com peso médio de 520 kg, distribuídas em delineamento experimental de triplo quadrado latino simultâneo. As taxas de glicose sangüínea das vacas foram consideradas normais, independente do volumoso utilizado. Em relação aos níveis de triglicerídeos, verificou-se que estão abaixo do normal para os diferentes volumosos. Uma das razões seria o baixo nível de gordura na dieta. Os níveis sangüíneos de uréia observados nos três tratamentos são considerados normais

The Pitzer-Lee-Kesler-Teja (PLKT) Strategy and Its Implementation by Meta-Computing Software

Czech Academy of Sciences Publication Activity Database

Smith, W. R.; Lísal, Martin; Missen, R. W.

2001-01-01

Roč. 35, č. 1 (2001), s. 68-73 ISSN 0009-2479 Institutional research plan: CEZ:AV0Z4072921 Keywords : The Pitzer -Lee-Kesler-Teja (PLKT) strategy * implementation Subject RIV: CF - Physical ; Theoretical Chemistry

Genetic polymorphisms in carnitine palmitoyltransferase 1A gene are associated with variation in body composition and fasting lipid traits in Yup'ik Eskimos[S

Science.gov (United States)

Lemas, Dominick J.; Wiener, Howard W.; O'Brien, Diane M.; Hopkins, Scarlett; Stanhope, Kimber L.; Havel, Peter J.; Allison, David B.; Fernandez, Jose R.; Tiwari, Hemant K.; Boyer, Bert B.

2012-01-01

Variants of carnitine palmitoyltransferase 1A (CPT1A), a key hepatic lipid oxidation enzyme, may influence how fatty acid oxidation contributes to obesity and metabolic outcomes. CPT1A is regulated by diet, suggesting interactions between gene variants and diet may influence outcomes. The objective of this study was to test the association of CPT1A variants with body composition and lipids, mediated by consumption of polyunsaturated fatty acids (PUFA). Obesity phenotypes and fasting lipids were measured in a cross-sectional sample of Yup'ik Eskimo individuals (n = 1141) from the Center of Alaska Native Health Research (CANHR) study. Twenty-eight tagging CPT1A SNPs were evaluated with outcomes of interest in regression models accounting for family structure. Several CPT1A polymorphisms were associated with HDL-cholesterol and obesity phenotypes. The P479L (rs80356779) variant was associated with all obesity-related traits and fasting HDL-cholesterol. Interestingly, the association of P479L with HDL-cholesterol was still significant after correcting for body mass index (BMI), percentage body fat (PBF), or waist circumference (WC). Our findings are consistent with the hypothesis that the L479 allele of the CPT1A P479L variant confers a selective advantage that is both cardioprotective (through increased HDL-cholesterol) and associated with reduced adiposity. PMID:22045927

New data on the epigraphy of Campo Real/Fillera (Sos del Rey Católico-Sangüesa

Directory of Open Access Journals (Sweden)

Javier ANDREU PINTADO

2010-07-01

Full Text Available The aim of this paper is to present the conclusions of two new epigraphic autopsies over two latin inscriptions –unpublished the first one, the second already known but here for the first time reviewed– found in the archaeological site of Campo Real/Fillera (Sos del Rey Católico-Sangüesa, in the northeast part of ancient Vascones’ territory. Some new archaeological materials related with the history of the monumentalization process of this ancient ciuitas are also presented: specially an spectacular funerary osteotheca made of stone with glass case, an unicum in the archeology of the death in the North-East part of the Iberian Peninsula. The paper is completed with a paleoanthropological and geological characterization of some of the most important evidences presented (including two pieces of green “campán” and turkish marble.

Ocean PHILLS Data Collection and Processing: May 2000 Deployment, Lee Stocking Island, Bahamas

National Research Council Canada - National Science Library

Leathers, Robert

2002-01-01

.... It was deployed in a region near Lee Stocking Island (LSI), Bahamas in May 2000. This document describes the LSI 2000 PHILLS data set and the manner in which it was processed to obtain remote-sensing reflectance images for use by the scientific community...

Comparison of Benedict-Webb-Rubin, Starling and Lee-Kesler equations of state for use in P-V-T calculations

International Nuclear Information System (INIS)

McFee, D.G.; Mueller, K.H.; Lielmezs, J.

1982-01-01

By means of the available experimental gas compressibility data, the predictive accuracy of the Benedict-Webb-Rubin, Starling and Lee-Kesler equations was tested over wide temperature and pressure ranges for the following commonly used industrial gases: CH 4 , C 2 H 6 , C 3 H 8 , CO 2 , Ar, He, H 2 and N 2 . The root mean square (RMS) percent errors calculated over the T-P range investigated for all compounds, showed a degree of superiority and ease of use of the Lee-Kesler equation over the Benedict-Webb-Rubin and Starling equations. In order to treat quantal fluids H 2 and He, the Benedict-Webb-Rubin equation was modified by making constant B 0 temperature dependent, while the Starling and Lee-Kesler equations were rewritten through inclusion of quantum effect corrected pseudo-critical state parameters. (orig.)

Feasibility of a community intervention for the prevention of suicide and alcohol abuse with Yup'ik Alaska Native youth: the Elluam Tungiinun and Yupiucimta Asvairtuumallerkaa studies.

Science.gov (United States)

Mohatt, Gerald V; Fok, Carlotta Ching Ting; Henry, David; Allen, James

2014-09-01

The Elluam Tungiinun and Yupiucimta Asvairtuumallerkaa studies evaluated the feasibility of a community intervention to prevent suicide and alcohol abuse among rural Yup'ik Alaska Native youth in two remote communities. The intervention originated in an Indigenous model of protection, and its development used a community based participatory research process. Feasibility assessment aimed to assess the extent to which (1) the intervention could be implemented in rural Alaska Native communities, and (2) the intervention was capable of producing measurable effects. Scales maximally sensitive to change were derived from earlier measurement work, and the study contrasted implementation process and outcomes across the two communities. In one community, medium dose response effects (d = .30-.50), with dose defined as number of intervention activities attended, were observed in the growth of intermediate protective factors and ultimate variables. In the other community, medium dose effects were observed for one intermediate protective factor variable, and small dose effects were observed in ultimate variables. Differences across communities in resources supporting intervention explain these contrasting outcomes. Results suggest implementation in these rural Alaska settings is feasible when sufficient resources are available to sustain high levels of local commitment. In such cases, measureable effects are sufficient to warrant a prevention trial.

77 FR 18852 - Lee Metcalf National Wildlife Refuge, Stevensville, MT; Draft Comprehensive Conservation Plan and...

Science.gov (United States)

2012-03-28

... business hours at the Lee Metcalf National Wildlife Refuge headquarters located at 4567 Wildfowl Lane... habitats and has created and modified wetlands. Riverfront forest includes early succession tree species...

Tuning of Lee Path Loss Model based on recent RF measurements in 400 MHZ conducted in Riyadh City, Saudi Arabia

International Nuclear Information System (INIS)

Alotaibi, Faihan D.; Ali, Adel A.

2008-01-01

In mobile radio systems, path loss models are necessary for proper planning, interference estimations, frequently assignments and cell parameters which are basic for network planning process as well as Location Based Services (LBS) techniques that are not based on GPS system. Empirical models are the most adjustable models that can be suited to different types of environments. In this paper, the Lee path loss model has been tuned using Least Square (LS) algorithm to fit measured data for TETRA system operating 400 MHz in Riyadh urban and suburbs. Consequently, Lee model's parameter (L0, y) are obtained for the targeted areas. The performance of the tuned Lee model is then compared to the three most widely used empirical path loss models: Hat, ITU-R and Cost 231 Walfisch-Ikegami non line-of-sight (CWI-NLOS) path loss models. The performance criterion selected for the comparison of various empirical path loss models are the Root Mean Square Error (RMSE) and goodness of fit (R2). The RMSE and R2between the actual and predicted data are calculated for various path loss models. It turned that the tuned Lee model outperforms the other empirical models. (author)

Lee as Critical Thinker: The Example of the Gettysburg Campaign

Science.gov (United States)

2012-05-04

importance were “ Hannibal , Frederick the Great, and especially Napoleon, all of whom were models for Lee as he led the Army of Northern Virginia in battle...Cannae, Leuthen, and Austerlitz. The Battle of Cannae culminated in a double envelopment by Hannibal against the Romans and “is important…because...it shows how Hannibal was able to completely surround a much larger force Roman force (40,000 versus 70,000, as compared with Lee’s 74,000 facing

Youth Culture, Language Endangerment and Linguistic Survivance

Science.gov (United States)

Wyman, Leisy

2012-01-01

Detailing a decade of life and language use in a remote Alaskan Yup'ik community, Youth Culture, Language Endangerment and Linguistic Survivance provides rare insight into young people's language brokering and Indigenous people's contemporary linguistic ecologies. This book examines how two consecutive groups of youth in a Yup'ik village…

Grey relational analysis for evaluating the effects of different rates of wine lees-derived biochar application on a plant-soil system with multi-metal contamination.

Science.gov (United States)

Xu, Min; Zhu, Qihong; Wu, Jun; He, Yan; Yang, Gang; Zhang, Xiaohong; Li, Li; Yu, Xiaoyu; Peng, Hong; Wang, Lilin

2018-03-01

In this study, grey relational analysis (GRA) was used to investigate the effects of different application rates of wine lees-derived biochar on a plant-soil system with multi-metal contamination. A pot experiment was conducted to determine rice growth in multi-metal-contaminated soil amended with samples of wine lees-derived biochar, and 47 indicators (including soil properties, microbial activity, and plant physiology) were selected as evaluation indexes to assess the plant-soil system. The results indicated that higher wine lees-derived biochar application rates (2% W/W) were favorable for soil fertility, the bioconcentration factor (BF), and the mobility factor (MF, %) (with the exception of Cr, Zn, and Hg), but an application of 1% produced the highest plant growth, enzymatic activities, and bacterial diversity. The richness of the bacterial communities was reduced in the soil amended with the wine lees-derived biochar. According to the GRA assessment, the 1% application rate of wine lees-derived biochar was more suitable for restoring the holistic plant-soil system than were the application rates of 0, 0.5, and 2% (W/W). Furthermore, this study shows that GRA is a useful method for evaluating plant-soil systems.

Nobelist TD LEE Scientist Cooperation Network and Scientist Innovation Ability Model

OpenAIRE

Fang, Jin-Qing; Liu, Qiang

2013-01-01

Nobelist TD Lee scientist cooperation network (TDLSCN) and their innovation ability are studied. It is found that the TDLSCN not only has the common topological properties both of scale-free and small-world for a general scientist cooperation networks, but also appears the creation multiple-peak phenomenon for number of published paper with year evolution, which become Nobelist TD Lee’s significant mark distinguished from other scientists. This new phenomenon has not been revealed in the scie...

Berners-Lee and the IPEN reality

International Nuclear Information System (INIS)

Sacramento, Jose Miguel Noronha; Rogero, Jose Roberto

2010-01-01

This article discusses a study held with researchers from IPEN and organizations that operate or could act as IPEN partners or clients on research projects and consumption of its products and services. The survey had its origin in the perception of the difficulties in alignment of IPEN with the demands of society, taking as a point of attention processes used in the disclosure and dissemination of scientific knowledge to the public other than the academic communities or specialists in the areas of IPEN usually operates. Were mapped communication flows between the researchers of IPEN and between companies and the IPEN so as to identify the necessary conditions to improve communication between different universes such as academic and business. The comparison of the conditions currently found in the IPEN with the 1991 initial proposal of Tim Berners-Lee when creating the World Wide Web to CERN and with web portals of organizations similar to IPEN provided valuable grants for the planning of next steps of IPEN organization in terms of its relationship with potential partners and, ultimately, the society. (author)

Efeitos das fontes e níveis de sódio, cloro e potássio e da relação (Na + K/Cl, sobre o desempenho e características do plasma sangüíneo de poedeiras comerciais

Directory of Open Access Journals (Sweden)

Junqueira Otto Mack

2000-01-01

Full Text Available Dois experimentos foram realizados para estudar os efeitos da relação (Na + K/Cl na dieta de poedeiras comerciais no final do ciclo de postura, pela adição de bicarbonato de sódio (NaHCO3, cloreto de sódio (NaCl, cloreto de potássio (KCl e cloreto de amônia (NH4Cl, avaliando-se os parâmetros produtivos e características do plasma sangüíneo. O primeiro experimento envolveu cinco tratamentos: 0,30% de NaCl; 0,30% de NaCl + 0,95% de NaHCO3; 0,38% de KCl + 0,67% de NaHCO3; 0,38% de KCl + 1,62% de NaHCO3; e 0,38% de KCL + 2,56% de NaHCO3. A relação (Na + K/Cl foi, respectivamente, 3,46; 4,46; 4,46; 5,46; e 6,46. O segundo experimento envolveu quatro tratamentos: 0,30% NaCl; 0,47% de NaHCO3 + 0,19 de NH4Cl; 1,17% NaHCO3 + 0,19% de NH4Cl; e 1,88% de NaHCO3 + 0,19% de NH4Cl. A relação (Na + K/Cl foi 3,46; 4,46; 5,46; e 6,46, respectivamente. No primeiro experimento, o maior consumo alimentar foi observado nas aves alimentadas com dietas contendo 0,30% de NaCl. As aves que consumiram KCl apresentaram melhor conversão alimentar. Foi observado aumento no fósforo e pH do plasma sangüíneo. Aves que receberam dietas em que a relação (Na +K/Cl foi de 5,46 apresentaram maiores níveis de fósforo no plasma sangüíneo. O aumento do pH no plasma sangüíneo foi observado em aves que receberam dietas com relações de (Na + K/Cl de 4,46 e 6,46. No segundo experimento, o peso do ovo diminuiu com o aumento do NaHCO3 da dieta.

Associação entre marcadores de grupos sangüíneos e produção à primeira lactação em bovinos da raça Gir Leiteiro

Directory of Open Access Journals (Sweden)

Conceição R.O.

2000-01-01

Full Text Available Foram analisados 138 resultados de tipagem sangüínea de animais da raça Gir Leiteiro, pertencentes a uma população fechada submetida a acasalamentos preferenciais por aproximadamente 30 anos. Estudou-se a associação entre os sistemas B, F, J, L e Z de grupos sangüíneos e a produção de leite à primeira lactação. Os resultados mostraram diferença significativa (P<0,001 na produção de leite das primíparas que possuem o fator Z, 3634,43kg, em relação as que não apresentaram o mesmo fator, 3074,62kg. Para o sistema B, por meio de contraste de médias, verificou-se que houve diferença significativa (P<0,05 entre animais com o fenogrupo I1O1Y2A?B?E?3(J?K?P?Q? em homozigose, 4202,86kg, e aqueles com os fenogrupos B(PQTE?3G?P?/I1O1Y2A?B?E?3(J?K?P?Q?, 3493,33kg, e BQTA?B?I?(P?/I1O1Y2A?B?E?3(J?K?P?Q?, 3630,36kg.

The Friedberg-Lee symmetry and minimal seesaw model

International Nuclear Information System (INIS)

He Xiaogang; Liao Wei

2009-01-01

The Friedberg-Lee (FL) symmetry is generated by a transformation of a fermionic field q to q+ξz. This symmetry puts very restrictive constraints on allowed terms in a Lagrangian. Applying this symmetry to N fermionic fields, we find that the number of independent fields is reduced to N-1 if the fields have gauge interaction or the transformation is a local one. Using this property, we find that a seesaw model originally with three generations of left- and right-handed neutrinos, with the left-handed neutrinos unaffected but the right-handed neutrinos transformed under the local FL translation, is reduced to an effective theory of minimal seesaw which has only two right-handed neutrinos. The symmetry predicts that one of the light neutrino masses must be zero.

THE YUAN-TSEH LEE ARRAY FOR MICROWAVE BACKGROUND ANISOTROPY

International Nuclear Information System (INIS)

Ho, Paul T. P.; Altamirano, Pablo; Chang, C.-H.; Chang, S.-H.; Chang, S.-W.; Chen, C.-C.; Chen, K.-J.; Chen, M.-T.; Han, C.-C.; Ho, West M.; Huang, Y.-D.; Hwang, Y.-J.; Ibanez-Romano, Fabiola; Jiang Homin; Koch, Patrick M.; Kubo, Derek Y.; Li, C.-T.; Lim, Jeremy; Lin, K.-Y.; Liu, G.-C.

2009-01-01

The Yuan-Tseh Lee Array for microwave background anisotropy is the first interferometer dedicated to study the cosmic microwave background radiation at 3 mm wavelength. The choice of 3 mm is to minimize the contributions from foreground synchrotron radiation and Galactic dust emission. The initial configuration of seven 0.6 m telescopes mounted on a 6 m hexapod platform was dedicated in 2006 October on Mauna Loa, Hawaii. Scientific operations began with the detection of a number of clusters of galaxies via the thermal Sunyaev-Zel'dovich effect. We compare our data with Subaru weak-lensing data to study the structure of dark matter. We also compare our data with X-ray data to derive the Hubble constant.

Acceleration of ageing on lees in red wines by application of ultrasounds

OpenAIRE

Fresno, Juan Manuel del; Morata Barrado, Antonio Dionisio; Loira, Iris; Escott, Carlos; Cuerda, Rafael; Calderon Fernandez, Fernando; Suarez Lepe, Jose Antonio

2017-01-01

A transfer of parietal polysaccharides and mannoproteins is produced during aging on lees [1]. This transfer of compounds to wine is carried out after cell death. It comes to breakdown of polysaccharides from cell wall (yeast autolysis). This technique increases the density in wines [2] and gives more body and structure. Interactions between yeast polysaccharides and wine tannins will result in decrease of tannic perception (decrease of astringency). Increase of varietal characteristics is pr...

The Brain Dead Patient Is Still Sentient: A Further Reply to Patrick Lee and Germain Grisez.

Science.gov (United States)

Austriaco, Nicanor Pier Giorgio

2016-06-01

Patrick Lee and Germain Grisez have argued that the total brain dead patient is still dead because the integrated entity that remains is not even an animal, not only because he is not sentient but also, and more importantly, because he has lost the radical capacity for sentience. In this essay, written from within and as a contribution to the Catholic philosophical tradition, I respond to Lee and Grisez's argument by proposing that the brain dead patient is still sentient because an animal with an intact but severed spinal cord can still perceive and respond to external stimuli. The brain dead patient is an unconscious sentient organism. © The Author 2016. Published by Oxford University Press, on behalf of the Journal of Medicine and Philosophy Inc. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Blood cell attachment to root surfaces treated with EDTA gel Adesão de células sangüíneas a superfícies radiculares tratadas com gel de EDTA

Directory of Open Access Journals (Sweden)

Fábio Renato Manzolli Leite

2005-06-01

Full Text Available Root debridement generates a smear layer which contains microorganisms and toxins that could interfere in periodontal healing. For this reason, different substances have been used to remove it and to expose collagen fibers at the tooth surface. Blood element adhesion to demineralized roots and clot stabilization by collagen fibers are extremely important for the success of periodontal surgery. The aim of this study was to evaluate the different patterns of blood element adsorption and adhesion to root surfaces only irrigated with distilled water and after application of a manipulated or an industrialized EDTA gel. Thirty samples were planed, equally divided into three groups and treated with distilled water (control, a manipulated EDTA gel or an industrialized one. Immediately after, samples were exposed to fresh blood and prepared for scanning electron microscopy. Untreated planed dentin presented the best results with blood cells entrapped in a thick web of fibrin. In the manipulated EDTA group, the web of fibrin was thick with sparse blood elements. The worst result was seen with the industrialized EDTA group, in which no blood elements could be seen. Statistical difference was obtained between control and industrialized EDTA groups. Surfaces only irrigated presented the most organized fibrin network and cell entrapment.A raspagem gera "smear layer", a qual contém microrganismos e toxinas que podem interferir no reparo periodontal. Por esse motivo, diferentes substâncias têm sido empregadas para remover esta camada e expor fibras colágenas da superfície dental. A adesão de elementos sangüíneos a superfícies radiculares desmineralizadas e a estabilização do colágeno pelas fibras colágenas são de extrema importância no sucesso da cirurgia periodontal. O objetivo deste estudo foi avaliar os diferentes padrões de adsorção e adesão de elementos sangüíneos a superfícies radiculares apenas irrigadas com água destilada e ap

Nonsingular cosmology with a scale-invariant spectrum of cosmological perturbations from Lee-Wick theory

International Nuclear Information System (INIS)

Cai Yifu; Qiu Taotao; Brandenberger, Robert; Zhang Xinmin

2009-01-01

We study the cosmology of a Lee-Wick type scalar field theory. First, we consider homogeneous and isotropic background solutions and find that they are nonsingular, leading to cosmological bounces. Next, we analyze the spectrum of cosmological perturbations which result from this model. Unless either the potential of the Lee-Wick theory or the initial conditions are finely tuned, it is impossible to obtain background solutions which have a sufficiently long period of inflation after the bounce. More interestingly, however, we find that in the generic noninflationary bouncing cosmology, perturbations created from quantum vacuum fluctuations in the contracting phase have the correct form to lead to a scale-invariant spectrum of metric inhomogeneities in the expanding phase. Since the background is nonsingular, the evolution of the fluctuations is defined unambiguously through the bounce. We also analyze the evolution of fluctuations which emerge from thermal initial conditions in the contracting phase. The spectrum of gravitational waves stemming from quantum vacuum fluctuations in the contracting phase is also scale-invariant, and the tensor to scalar ratio is not suppressed.

Desvios porta-jugular e cava-jugular passivos em cães: Investigação de pressões sangüíneas

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Coelho Antônio Roberto Barros

1999-01-01

Full Text Available Os principais objetivos dos desvios veno-venosos durante o transplante ortotópico de fígado são: atenuação da estase venosa subdiafragmática, manutenção do retorno satisfatório de sangue ao coração e perfusão tissular eficiente. Investigações sobre PP, PVCIIH, PVC, PAM e PPR, bem como D PP e D PVCIIH foram conduzidas em seis cães, sob anestesia geral, com fígados perfundidos pela Artéria Hepática, submetidos a desvios porta-jugular e cava-jugular passivos durante 2 horas. Estes desvios não foram capazes de evitar estagnação de sangue na VP e VCIIH, acarretando estase e menor retorno sangüíneo ao coração, sugeridos por aumentos significativos de PP e PVCIIH e quedas significantes nos níveis de PVC. Os valores de PAM não apresentaram diferenças significativas em relação ao tempo T0, na maior parte dos tempos avaliados, enquanto que os valores de PPR foram significativamente menores que os verificados no tempo T0, na maioria dos tempos estudados. Tais pressões mantiveram-se, respectivamente, acima de 100 e 50 mm de Hg, atribuindo-se tais resultados, em parte, à vasoconstricção arteriolar generalizada. Incrementos de pressão na VP (D PP foram significativamente menos elevados que aqueles verificados na VCIIH (D PVCIIH, atribuindo-se tal diferença à complacência esplâncnica. Decréscimos ulteriores dos níveis de PP e PVCIIH sugerem queda do fluxo arterial para os territórios esplâncnico e sistêmico, decorrente de diminuição do retorno sangüíneo ao coração. Determinações de PP, PVCIIH, PVC, PAM e PPR podem constituir meio prático de avaliação hemodinâmica do desvio veno-venoso.

Fighting with Reality: Considering Mark Johnson's Pragmatic Realism through Bruce Lee's Jeet Kune Do Method

Science.gov (United States)

Miller, Alexander David

2015-01-01

This dissertation considers the supportive and complementary relation between Mark Johnson's embodied realism and Bruce Lee's Jeet Kune Do as a philosophical practice. In exploring this relationship, the emphasis on one's embodiment condition and its relationship with metaphor and self-expression are the primary focus. First, this work involves…

77 FR 14032 - John H. Chafee Coastal Barrier Resources System; Lee County, FL, and Newport County, RI...

Science.gov (United States)

2012-03-08

... conduct a comprehensive review of the history of the CBRS unit in question. The Service has a large... by Lee County, and 1 restaurant. The Service's assessment of 2011 aerial imagery estimates that the...

Functional renormalization group approach to the Yang-Lee edge singularity

Energy Technology Data Exchange (ETDEWEB)

An, X. [Department of Physics, University of Illinois at Chicago,845 W. Taylor St., Chicago, IL 60607 (United States); Mesterházy, D. [Albert Einstein Center for Fundamental Physics, University of Bern,Sidlerstrasse 5, 3012 Bern (Switzerland); Stephanov, M.A. [Department of Physics, University of Illinois at Chicago,845 W. Taylor St., Chicago, IL 60607 (United States)

2016-07-08

We determine the scaling properties of the Yang-Lee edge singularity as described by a one-component scalar field theory with imaginary cubic coupling, using the nonperturbative functional renormalization group in 3≤d≤6 Euclidean dimensions. We find very good agreement with high-temperature series data in d=3 dimensions and compare our results to recent estimates of critical exponents obtained with the four-loop ϵ=6−d expansion and the conformal bootstrap. The relevance of operator insertions at the corresponding fixed point of the RG β functions is discussed and we estimate the error associated with O(∂{sup 4}) truncations of the scale-dependent effective action.

Analysis of the membrane fouling on cross-flow ultrafiltration and microfiltration of soy sauce lees; Shoyuhiireden no kurosuforo roka ni okeru fauringu no kaiseki

Energy Technology Data Exchange (ETDEWEB)

Furukakwa, T. [Kikkoman Corporation, Chiba (Japan); Kobayashi, H.; Kokubo, K.; Watanabe, A. [Niigata University, Niigata (Japan). Graduate School of Science and Technology

2000-05-10

Although since the 1980's Japanese soy sauce manufactures have developed cross-flow membrane filtration systems to recover soy sauce from its lees, the mechanisms by which the membrane fouls during filtration have not been theoretically discussed. Calculated flux declines using a theoretical equation developed for cross-flow cake filtration were compared against experimental results involving the filtration of soy sauce lees using polysulfone ultrafiltration and micro filtration membranes. Membrane fouling due to the deposition and intrusion of soy sauce lees was evaluated from the hydraulic resistances of the membrane and the cake layer. Calculated flux declines with time agree with the experimental results. Specific resistance of the cake layer which is an adjustable parameter of the equation, decreases with increasing cross-flow velocity. Hydraulic resistance exhibited by the membranes is independent of feed flow velocity. However, the resistance of the cake layers decreases with increasing cross-flow velocity. This corresponds to the steady-state flux increase. In conclusion, the main cause of fouling in the filtration of soy sauce lees is cake layer formation. By using the cake filtration model for cross-flow, the flux decline with time during the filtration is capable of being predicted. (author)

Diversity, threats and conservation of catfish fauna of the Krishna River, Sangli District, Maharashtra, India

Directory of Open Access Journals (Sweden)

S.M. Kumbar

2014-01-01

Full Text Available The diversity of freshwater catfish species of the Krishna River, Sangli District was studied from June 2009 to July 2012. The study area covered 105km from Karad City where the Koyna tributary joins the Krishna River up to Mhaishal, the state border of Maharashtra. It was divided into three streams for convenience, i.e., the upper stream starts from Karad and goes up to Takari, the middle stream from Takari to Bhilawadi and downstream from Bhilawadi to Mhaishal. A total of 13 species of catfish belonging to five families and 10 genera were recorded. The Bagridae family was dominant with six species, whereas Siluridae, Schilbidae and Clariidae had two species each and Sisoridae with one species. We have provided range extension for an endemic and threatened sisorid catfish Glyptothorax poonaensis. The occurrence and distribution of catfishes was more or less equal in number along the study area. The maximum number of species recorded was nine from the upper stream, whereas the middle and down streams had eight and seven species respectively. The distribution of catfish along the Krishna River system may be due to the slow and steady state water movement and its width that ensure the continuous availability of nutrition. It is suggested that the Krishna River would be a suitable habitat for the conservation of freshwater catfish if the threats are minimized.

”I sangen møtes vi på felles grunn.” Om sang og sangbøker i norsk skole.

Directory of Open Access Journals (Sweden)

Ragnhild Elisabeth Lund

2010-12-01

Full Text Available Sangfaget har en lang og sterk tradisjon i den norske skolestua og sangboka har vært et sentralt læremiddel i mer enn 150 år. Formålet med denne artikkelen er å belyse de mange og ulike begrunnelser som er blitt knyttet til faget opp gjennom tidene og å vise hvilket innhold sangbøkene har søkt å formidle. Presentasjonen av sangfagets begrunnelser er basert på en undersøkelse av skolehistoriske tekster og læreplaner fra tidlig på 1800-tallet fram til vår tid. Jeg har også sett på forordene og forfatternes vektlegging av sangrepertoar og annet sang- og musikkfaglig innhold i de mest toneangivende sangbøkene fra samme periode. For å finne ut hvilke sanger elevene er blitt tilbudt og hvilke verdier sangene formidler, har jeg kartlagt repertoarvalget i tolv sangbokverk fra 1850 (Behrens’ Skolesangbog til 2008 (Amsrud & Bjørnstads Sang i Norge. Artikkelen viser at begrunnelsene for sangfaget favner vidt og at både de og innholdet i sangbøkene har endret seg i takt med utviklingen i utdanningssystemet og i samfunnet forøvrig. Videreformidling av sentrale sanger i norsk kulturarv har selvsagt stått sentralt. Men sangfaget har også befattet seg med opplæring i musikkteori, notelære og stemmepleie, og det har hatt som oppgave å utvikle kvalitetsbevissthet, samhold og fellesskap i tillegg til å bidra til læring og trivsel i andre fag. Når det gjelder repertoarvalg, har utviklingen gått fra en hovedvekt på sanger med et religiøst og oppdragende innhold via nasjonale sanger til en stadig økende andel ”blott-til-lyst-sanger” og sanger fra populærmusikkens område. Til tross for at repertoarvalget har endret seg, er det mange sanger som går igjen gjennom hele perioden. Med referanse til en definisjon av kanon som ”stabile forekomster” identifiserer artikkelen 34 sanger som kan sies å utgjøre en del av ”den norske sangskatten”.

Distribution of non-LEE-encoded type 3 secretion system dependent effectors in enteropathogenic Escherichia coli

Directory of Open Access Journals (Sweden)

Fábia A. Salvador

2014-09-01

Full Text Available Enteropathogenic Escherichia coli (EPEC are important human gastroenteritis agents. The prevalence of six non-LEE genes encoding type 3 translocated effectors was investigated. The nleC, cif and nleB genes were more prevalent in typical than in atypical EPEC, although a higher diversity of genes combinations was observed in atypical EPEC.

Generation of hyperchaos from the Chen-Lee system via sinusoidal perturbation

International Nuclear Information System (INIS)

Tam, L.M.; Chen, J.H.; Chen, H.K.; Wai Meng Si Tou

2008-01-01

A system with more than one positive Lyapunov exponent can be classified as a hyperchaotic system. In this study, a sinusoidal perturbation was designed for generating hyperchaos from the Chen-Lee chaotic system. The hyperchaos was identified by the existence of two positive Lyapunov exponents and bifurcation diagrams. The system is hyperchaotic in several different regions of the parameters c, ε, and ω. It was found that this method not only can enhance or suppress chaotic behavior, but also induces chaos in non-chaotic parameter ranges. In addition, two interesting dynamical behaviors, Hopf bifurcation and intermittency, were also found in this study

Generation of hyperchaos from the Chen-Lee system via sinusoidal perturbation

Energy Technology Data Exchange (ETDEWEB)

Tam, L.M. [Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Av. Padre Thomas Pereira S.J., Taipa, Macau (China)], E-mail: fstlmt@umac.mo; Chen, J.H. [Department of Mechanical Engineering, Chung Hua University, Hsinchu, Taiwan (China); Chen, H.K. [Department of Mechanical Engineering, Hsiuping Institute of Technology, Taichung, Taiwan (China); Wai Meng Si Tou [Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Av. Padre Thomas Pereira S.J., Taipa, Macau (China)

2008-11-15

A system with more than one positive Lyapunov exponent can be classified as a hyperchaotic system. In this study, a sinusoidal perturbation was designed for generating hyperchaos from the Chen-Lee chaotic system. The hyperchaos was identified by the existence of two positive Lyapunov exponents and bifurcation diagrams. The system is hyperchaotic in several different regions of the parameters c, {epsilon}, and {omega}. It was found that this method not only can enhance or suppress chaotic behavior, but also induces chaos in non-chaotic parameter ranges. In addition, two interesting dynamical behaviors, Hopf bifurcation and intermittency, were also found in this study.

Lee-Yang zeroes and logarithmic corrections in the Φ44 theory

International Nuclear Information System (INIS)

Kenna, R.; Lang, C.B.

1993-01-01

The leading mean-field critical behaviour of φ 4 4 -theory is modified by multiplicative logarithmic corrections. We analyse these corrections both analytically and numerically. In particular we present a finite-size scaling theory for the Lee-Yang zeroes and temperature zeroes, both of which exhibit logarithmic corrections. On lattices from size 8 4 to 24 4 , Monte-Carlo cluster methods and multi-histogram techniques are used to determine the partition function zeroes closest to the critical point. Finite-size scaling behaviour is verified and the logarithmic corrections are found to be in good agreement with our analytical predictions. (orig.)

Stick, Carrot and Skill Acquisition

DEFF Research Database (Denmark)

Filges, Trine; Larsen, Birthe

This paper examines the macroeconomic effects of youth unemployment programmes in the form of vocational training (YUPs), developing a two sector general equilibrium model featuring matching frictions and worker-firm wage bargaining for skilled workers.......This paper examines the macroeconomic effects of youth unemployment programmes in the form of vocational training (YUPs), developing a two sector general equilibrium model featuring matching frictions and worker-firm wage bargaining for skilled workers....

Electricity generation using white and red wine lees in air cathode microbial fuel cells

Science.gov (United States)

Pepe Sciarria, Tommy; Merlino, Giuseppe; Scaglia, Barbara; D'Epifanio, Alessandra; Mecheri, Barbara; Borin, Sara; Licoccia, Silvia; Adani, Fabrizio

2015-01-01

Microbial fuel cell (MFC) is a useful biotechnology to produce electrical energy from different organic substrates. This work reports for the first time results of the application of single chamber MFCs to generate electrical energy from diluted white wine (WWL) and red wine (RWL) lees. Power obtained was of 8.2 W m-3 (262 mW m-2; 500 Ω) and of 3.1 W m-3 (111 mW m-2; 500Ω) using white and red wine lees, respectively. Biological processes lead to a reduction of chemical oxygen (TCOD) and biological oxygen demand (BOD5) of 27% and 83% for RWL and of 90% and 95% for WWL, respectively. These results depended on the degradability of organic compounds contained, as suggest by BOD5/TCOD of WWL (0.93) vs BOD5/TCOD of RWL (0.33), and to the high presence of polyphenols in RWL that inhibited the process. Coulombic efficiency (CE) of 15 ± 0%, for WWL, was in line with those reported in the literature for other substrates, i.e. CE of 14.9 ± 11.3%. Different substrates led to different microbial consortia, particularly at the anode. Bacterial species responsible for the generation of electricity, were physically connected to the electrode, where the direct electron transfer took place.

Comments, with reply, on 'Parallel resonant converter with LLC-type commutation' by C. Q. Lee et al.

Science.gov (United States)

Hamill, David C.

1991-05-01

In a recent paper by Lee et al. (1989), the authors analyzed a DC-DC converter that they termed the LLC-type PRC (parallel resonant converter). Its resonant network contains three active components-two inductances and a parallel capacitance -and as a consequence the the converter might be expected to have third-order dynamics. But Lee et al. employed a matrix transformation to show that the behavior of the circuit may be represented as a state-plane trajectory, as for a second-order circuit. The purpose of this contribution is to show that the converter has a zero-frequency eigenvalue, associated with undesirable circulating DC. The second-order dynamics exhibited by the third-order converter are explained by an application of Thevenin's theorem. Some aerospace applications of the LLC-type parallel resonant converter (PRC) are discussed. In their reply, the authors show that the circulating direct current does not exist in the practical converter circuit.

Analyses and optimization of Lee propagation model for LoRa 868 MHz network deployments in urban areas

Directory of Open Access Journals (Sweden)

Dobrilović Dalibor

2017-01-01

Full Text Available In the recent period, fast ICT expansion and rapid appearance of new technologies raised the importance of fast and accurate planning and deployment of emerging communication technologies, especially wireless ones. In this paper is analyzed possible usage of Lee propagation model for planning, design and management of networks based on LoRa 868MHz technology. LoRa is wireless technology which can be deployed in various Internet of Things and Smart City scenarios in urban areas. The analyses are based on comparison of field measurements with model calculations. Besides the analyses of Lee propagation model usability, the possible optimization of the model is discussed as well. The research results can be used for accurate design, planning and for preparation of high-performance wireless resource management of various Internet of Things and Smart City applications in urban areas based on LoRa or similar wireless technology. The equipment used for measurements is based on open-source hardware.

78 FR 77508 - Duke Energy Carolinas, LLC; William States Lee III Nuclear Station, Units 1 and 2; Combined...

Science.gov (United States)

2013-12-23

... NUCLEAR REGULATORY COMMISSION [Docket Nos. 52-018 and 52-019; NRC-2008-0170] Duke Energy Carolinas, LLC; William States Lee III Nuclear Station, Units 1 and 2; Combined Licenses Application Review AGENCY: Nuclear Regulatory Commission. ACTION: Final environmental impact statement; availability...

Lee Silverman Voice Treatment for People with Parkinson's: Audit of Outcomes in a Routine Clinic

Science.gov (United States)

Wight, Sheila; Miller, Nick

2015-01-01

Background: Speaking louder/more intensely represents a longstanding technique employed to manage voice and intelligibility changes in people with Parkinson's. This technique has been formalized into a treatment approach and marketed as the Lee Silverman Voice Treatment (LSVT®) programme. Evidence for its efficacy has been published. Studies…

Quantum-statistical mechanics of an atom-dimer mixture: Lee-Yang cluster expansion approach

International Nuclear Information System (INIS)

Ohkuma, Takahiro; Ueda, Masahito

2006-01-01

We use the Lee-Yang cluster expansion method to study quantum-statistical properties of a mixture of interconvertible atoms and dimers, where the dimers form in a two-body bound state of the atoms. We point out an infinite series of cluster diagrams whose summation leads to the Bose-Einstein condensation of the dimers below a critical temperature. Our theory captures some important features of a cold atom-dimer mixture such as interconversion of atoms and dimers and properties of the mixture at the unitarity limit

Adaptation of Sing Lee's model to the Filippov type plasma focus geometry

International Nuclear Information System (INIS)

Siahpoush, V; Tafreshi, M A; Sobhanian, S; Khorram, S

2005-01-01

A new model for plasma behaviour in Filippov type plasma focus (PF) systems has been described and used. This model is based on the so-called slug model and Sing Lee's model for Mather type PF devices. Using the model, the discharge current and its derivative as a function of time, and the pinch time and the maximum discharge current as a function of pressure, have been predicted. At the end, the predicted data are compared with the experimental data obtained through a Filippov type PF facility with a nominal maximum energy of 90 kJ

Visioni vittoriane: il paesaggio fiorentino nelle opere di Janet Ross e Vernon Lee

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Gabriele Corsani

2015-11-01

Full Text Available Fra l’ultimo scorcio dell’Ottocento e i primi decenni del Novecento Firenze e i suoi dintorni sono il soggetto privilegiato di una grande quantità di descrizioni, note di diario, racconti, opera di scrittori stranieri, in particolare inglesi, che si radicano nell’approdo elettivo di quei luoghi. Il testo presenta la traccia letteraria del paesaggio fiorentino nelle opere di Vernon Lee e Janet Ross, due tipiche rappresentanti di questa tendenza che hanno vissuto, attraverso vicende biografiche in qualche modo parallele, un’esperienza di intensa identificazione con il paesaggio fiorentino. Di Janet Ross, viene commentato Old Florence and Modern Tuscany, volume che raccoglie una serie di articoli pubblicati su alcune riviste inglesi e fornisce una efficace panoramica sull’interesse molto concreto di Janet Ross per il mondo rurale che la vede addirittura impegnata nella gestione della fattoria di Castagnolo, a Lastra a Signa. Più sfaccettato è il commento alle opere di Vernon Lee, di cui sono commentati passi da Vanitas. Polite Stories, Genius Loci, Hortus Vitae and Limbo, in virtù della maggiore ampiezza e complessità del suo mondo culturale. Ne sono cifra distintiva la associazione fra storia e realtà attraverso la dimensione del mistero, che risulta una delle chiavi di acccesso alla bellezza e alla vitalità del paesagggio e la capacità di cogliere il ritmo proprio dei luoghi e di entrare in reale sintonia con essi. 

James Lee Byars 1/2 an autobiography, sourcebook

CERN Document Server

Byars, James Lee; Eleey, Peter

2014-01-01

"I see my autobiography as an arbitrary segment of so many pages of time, of things that I have paid attention to at this point in my life," wrote James Lee Byars (1932-1997) in 1969. He was then 37, about half the average male lifespan at the time, and accordingly thought it appropriate to write his "1/2 autobiography." Byars' art ranged from highly refined objects to extremely minimal performance and events, and books, ephemera and correspondence that he distributed widely among friends and colleagues. Today, more than 15 years after his death, assessments of his art must negotiate Byars' performance of his charismatic self in his life and art. For his first major posthumous survey in the US, exhibition curators Magalí Arriola and Peter Eleey decided to produce a catalogue in two "halves," playing on his "1/2 autobiography": a catalogue of the exhibition itself, including new scholarship, and a sourcebook of primary documents. 1/2 an Autobiography, Sourcebook constitutes the latter volume--a reference guid...

Fungal and enzymatic remediation of a wine lees and five wine-related distillery wastewaters

CSIR Research Space (South Africa)

Strong, PJ

2008-09-01

Full Text Available The alcohol fermentation industry is divided into three main categories: brewing, distilling and wine manufacture. Each of these categories produces wastewaters with com- mon characteristics, such as acidic pH values and high bio- chemical oxygen demand....O. Box 94, Grahamstown 6140, South Africa , Pretoria 0001, South Africa 6 December 2007; accepted 12 December 2007 (2008) xxx–xxx and enzymatic remediation of a wine lees and five ..., Bioresour. e ARTICLE IN PRESS Distillery and wine...

Educational Values of the Dream and Reality Psychoanalysis In “Sang Pemimpi” (the Dreamer, a Novel by Andrea Hirata

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Muhammad Nasir

2015-02-01

Full Text Available This article tries to look at psychoanalysis study of a novel concerning on the dream and reality in Sang Pemimpi (the Dreamer by Andrea Hirata. In general, his work portrays mostly about the condition and situational life of Belitung community. Here, Andrea shows his ability as the representative of Belitung's young generation succeeded in fulfilling his dream by explaining the real life of the people in his hometown and villages having bitter experience values in the rich environment. Besides, he tries to describe the difficult life faced by the villagers. The dream in this novel is not only his, but also all dreams of the Belitung community as the manifestation of their life condition comparing to other areas or provinces in the Indonesia. Further, through this novel (work, it is implied an important massage directed to both Indonesian authority and Belitung mayor in order to be able to increase the level of education of grass root community, especially for those who live in the remote area or a very isolated area, such as Belitung. This is the real dream of all participants in the island which remains unsolved.

Cardioplegia sangüínea contínua normotérmica Normotermic continuous blood cardioplegy

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Domingo M Braile

1989-08-01

Full Text Available Os autores discutem o emprego da cardioplegia, bem como sua composição. A parada imediata dos batimentos pode ser conseguida com soluções cardioplégicas cristalóides ou sangüíneas, oxigenadas ou não. O agente que leva o coração à parada pode ser potássio, magnésio, procaína ou, mesmo, quelantes e bloqueadores de cálcio associados entre si ou não, contando com a edição da hipotermia ou não. Deve-se ficar atento para a falsa sensação de proteção a que a baixa temperatura possa nos induzir, uma vez que o frio, por si só, não é suficiente para manter o miocárdio viável por longos períodos. Substratos, como glicose e oxigênio, devem ser fornecidos durante o período de clampeamento aórtico, para garantir algum metabolismo aeróbio, nesse período. A adição de outros substratos, como glutamato, aspartato e lactato, assim como ATP ou creatina fosfato, precursores de intermediários do ciclo de Krebs, podem melhorar muito a proteção miocárdica. A infusão de cardioplegia sangüínea normotérmica de forma contínua mantém as necessidades metabólicas básicas para a sobrevivência das células. A membrana celular, com todas as suas funções estruturais e secretoras, é o ponto mais sensível à injúria isquêmica. Os removedores de radicais livres (scavengers são protetores indiretos da membrana celular. A cardioplegia retrógrada permite melhorar a distribuição das soluções na árvore coronariana, sendo muito útil nas reoperações. Ela deve fazer parte da tática cirúrgica, sem esquecermos suas limitações. O momento da reperfusão é o mais importante da proteção miocárdica; é nesse período que ocorre a liberação de radicais livres. O uso de removedores (scavengers pode melhorar as condições e o resultado da reperfusão. A cardioplegia sangüínea oxigenada e normotérmica enriquecida com substratos, antes usada em casos extremamente graves, por disfunção muscular em isquemia mioc

Reference values for chinchilla (Chinchilla laniger blood cells and serum biochemical parameters Valores de referência para os parâmetros das células e bioquímica sangüínea da chinchila (Chinchilla laniger

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Tális de Oliveira Silva

2005-06-01

Full Text Available Raising chinchilla (Chinchilla laniger for commercial purpose has increased significantly; however, hematological and serum biochemical reference values have not yet been determined for chinchillas raised in south Brazil. Establishing blood cells and serum biochemistry reference values might be helpful to evaluate health status of chinchillas and might be used as a tool by clinicians. The purpose of this study was to determine the reference values for blood cells and serum biochemistry of Chinchilla laniger. Blood samples were collected by cardiac puncture from 16 adult males, at the time they were killed to remove the fur coat, and from 8 adult males anesthetized with ketamine and xylazine. Blood cell counts and serum biochemistry analysis were performed using standard techniques and the results were expressed as mean ± SEM. Analysis of blood parameters from post-mortem cardiac punctured and from anesthetized chinchillas indicated that blood samples from anesthetized chinchillas had higher PCV, Hemoglobin, MCHC and WBC (P A criação de chinchila (Chinchilla laniger com objetivos comerciais tem crescido muito nos últimos anos. No entanto, os valores de referência para os parâmetros hematológicos e bioquímicos não foram ainda determinados para chinchilas criados no sul do Brasil. O estabelecimento dos valores de referência para esses parâmetros pode servir de auxílio para a avaliação da saúde das chinchilas e servir de auxílio diagnóstico para o clínico. Esse estudo teve como objetivo determinar os valores de referência das células e da bioquímica sangüínea da Chinchilla laniger. As amostras de sangue foram coletadas por meio de punção cardíaca de 16 machos adultos no momento em que os animais foram mortos para remoção da pele, e de 8 machos adultos após anestesia com xylazina e ketamina. A contagem das células sangüíneas e a análise dos parâmetros bioquímicos foram feitas utilizando-se métodos padronizados em

Lung function decline rates according to GOLD group in patients with chronic obstructive pulmonary disease

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Kim J

2015-09-01

Full Text Available Joohae Kim,1 Ho Il Yoon,2 Yeon-Mok Oh,3 Seong Yong Lim,4 Ji-Hyun Lee,5 Tae-Hyung Kim,6 Sang Yeub Lee,7 Jin Hwa Lee,8 Sang-Do Lee,3 Chang-Hoon Lee11Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, 2Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, 3Department of Pulmonary and Critical Care Medicine and Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, 4Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, 5Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, 6Division of Pulmonology, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, 7Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Korea University, 8Department of Internal Medicine, Ewha Womans University Mokdong Hospital, College of Medicine, Ewha Womans University, Seoul, Republic of KoreaBackground: Since the Global Initiative for Chronic Obstructive Lung Disease (GOLD groups A-D were introduced, the lung function changes according to group have been evaluated rarely.Objective: We investigated the rate of decline in annual lung function in patients categorized according to the 2014 GOLD guidelines.Methods: Patients with COPD included in the Korean Obstructive Lung Disease (KOLD prospective study, who underwent yearly postbronchodilator spirometry at least three times, were included. The main outcome was the annual decline in postbronchodilator forced expiratory volume in 1 second (FEV1, which was analyzed by

A Note to Our Readers

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Wen-hsin Yeh

2013-12-01

Full Text Available We are pleased to introduce the ninth issue of the Cross-Currents e-journal. The research articles in this special issue guest edited by John Lie (UC Berkeley are connected by the theme “The Globalization of K-pop: Local and Transnational Articulations of South Korean Popular Music.” These articles by Nissim Otmazgin and Irina Lyan (both of Hebrew University Jerusalem, Ingyu Oh (Korea University, Hyo-Jung Lee (Yongsei University, and Sang-yeon Sung (University of Vienna, along with a contribution by guest editor Lie. Together, they discuss the performance and consumption of Korean popular music in Palestine, Israel, South Korea, Austria, and Japan in order to explore the complex dynamics between local fans and global pop culture...

Numerical Simulation of Wake Effects in the Lee of a Farm of Wave Dragon Wave Energy Converters

DEFF Research Database (Denmark)

Beels, C.; Troch, P.; De Visch, K.

2009-01-01

. In this paper wake effects in the lee of a single Wave Dragon WEC and multiple Wave Dragon WECs are studied in a time-dependent mild-slope equation model. The Wave Dragon WEC is a floating offshore converter of the overtopping type. The water volume of overtopped waves is first captured in a basin above mean...

Sometimes Pursuits Don't Pan Out: Anticipated Destinations and Other Caveats--Comment on Hom, Mitchell, Lee, and Griffeth (2012)

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Bergman, Mindy E.; Payne, Stephanie C.; Boswell, Wendy R.

2012-01-01

Hom, Mitchell, Lee, and Griffeth (2012) presented an extensive review of employee turnover research, reconceptualized the turnover criterion to include multiple destinations, and proposed to expand the predictor domain. They illuminated the multiple destinations employees pursue following turnover. By crossing desire to remain and volitional…

The Effects of Benefits, Incentives, and Sanctions on Youth Unemployment

DEFF Research Database (Denmark)

Rosholm, Michael; Jensen, Peter S.; Nielsen, Michael Svarer

1999-01-01

The youth unemployment rate in Denmark has recently been declining dramatically, which is unique among the OECD countries. In 1996, a radical labour market reform was implemented, the Youth Unemployment Programme (YUP), directed towards unemployed, low-educated youth. This paper analyses the effe......The youth unemployment rate in Denmark has recently been declining dramatically, which is unique among the OECD countries. In 1996, a radical labour market reform was implemented, the Youth Unemployment Programme (YUP), directed towards unemployed, low-educated youth. This paper analyses...

Finite-volume spectra of the Lee-Yang model

Energy Technology Data Exchange (ETDEWEB)

Bajnok, Zoltan [MTA Lendület Holographic QFT Group, Wigner Research Centre for Physics,H-1525 Budapest 114, P.O.B. 49 (Hungary); Deeb, Omar el [MTA Lendület Holographic QFT Group, Wigner Research Centre for Physics,H-1525 Budapest 114, P.O.B. 49 (Hungary); Physics Department, Faculty of Science, Beirut Arab University (BAU),Beirut (Lebanon); Pearce, Paul A. [School of Mathematics and Statistics, University of Melbourne,Parkville, Victoria 3010 (Australia)

2015-04-15

We consider the non-unitary Lee-Yang minimal model M(2,5) in three different finite geometries: (i) on the interval with integrable boundary conditions labelled by the Kac labels (r,s)=(1,1),(1,2), (ii) on the circle with periodic boundary conditions and (iii) on the periodic circle including an integrable purely transmitting defect. We apply φ{sub 1,3} integrable perturbations on the boundary and on the defect and describe the flow of the spectrum. Adding a Φ{sub 1,3} integrable perturbation to move off-criticality in the bulk, we determine the finite size spectrum of the massive scattering theory in the three geometries via Thermodynamic Bethe Ansatz (TBA) equations. We derive these integral equations for all excitations by solving, in the continuum scaling limit, the TBA functional equations satisfied by the transfer matrices of the associated A{sub 4} RSOS lattice model of Forrester and Baxter in Regime III. The excitations are classified in terms of (m,n) systems. The excited state TBA equations agree with the previously conjectured equations in the boundary and periodic cases. In the defect case, new TBA equations confirm previously conjectured transmission factors.

Geochronology, radiogenic isotope geochemistry, and petrogenesis of Sang bast Paleo-tethys monzogranite, Mashhad, Iran

International Nuclear Information System (INIS)

Karimpour, M. H.; Farmer, G.L.; Stern, C.R.

2010-01-01

The study area is located in northeastern Iran (south of Mashhad). Paleo-Tethys Ocean opened during Silurian time and subduction under Turan plate was started in Late Devonian. By Late Triassic (225 Ma) there was no Paleo-Tethys left on an Iranian transect, therefore Turan plate obducted over Iran Plate. Two stages of low grade regional metamorphism are exposed, that are related to Hercynian (Late Paleozoic) and Cimmerian (Jurassic) oro genies. The Paleo-Tethys remnants (meta-ophiolite and meta-flysch) were intruded by Sang bast monzogranite. Chemically, monzogranite is moderately peraluminous S-type granitoid. It has low values of magnetic susceptibility [(5 to 11) * 10 -5 SI] therefore it is classified as belonging to the ilmenite-series of reduced type granitoids. Monzogranite is characterized by strong light rare earth element enrichment and less low heavy rare earth element. All samples have very small negative Eu anomalies (Eu/Eu * = 0.62 to 0.88). Total rare earth element content of monzogranite is between 212-481 ppm. The result of U-Pb zircon age dating of monzogranite is 201.3 ± 3.6 Ma (Upper Triassic, Rhaetian time). The initial 87 Sr/ 86 Sr and 143 Nd/ 144 Nd ratios for monzogranite is (0.706776 and 0.512219) when recalculated to an age of 201 Ma, consistent with the new radiometric. The initial 87 Sr/ 86 Sr and 143 Nd/ 144 Nd ratios for slate is (0.720613 and 0.511601) respectively when recalculated to an age of 201 Ma, consistent with the new radiometric results. Initial εNd isotope values for monzogranite is -3.13 and the slate is -15.19. Based on radiogenic isotopic data and rare earth element monzogranite magma originated either from lower continental crust which was very different from slate or it is originated from mantle and contaminated in continental crust during ascending.

Further Clarifying Proximal Withdrawal States and the Turnover Criterion Space: Comment on Hom, Mitchell, Lee, and Griffeth (2012)

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Maertz, Carl P., Jr.

2012-01-01

In "Reviewing Employee Turnover: Focusing on Proximal Withdrawal States and an Expanded Criterion," Hom, Mitchell, Lee, and Griffeth (2012) brought together many of the most important content and process factors in the employee turnover literature. In this paper, I attempt to clarify the true contributions of this framework for the turnover area…

Comment on "Combination of cupric ion with hydroxylamine and hydrogen peroxide for the control of bacterial biofilms on RO membranes by Hye-Jin Lee, Hyung-Eun Kim, Changha Lee [Water Research 110, 2017, 83-90]".

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Chen, Long; Peng, Ying; Tang, Min; Wu, Feng

2017-07-01

The methodology employed by Lee et al. to terminate their bactericidal assays was found to be flawed via our demonstrations. Briefly, EDTA or sulfite combining with cupric ion did not fully terminate, and instead even boosted the P. aeruginosa death. We therefore suggested them to seek for other means of reaction termination, such as the combination of buffering agent PBS and Cu(II)-complexing agent EDTA. Copyright © 2017 Elsevier Ltd. All rights reserved.

Characterization of mannoproteins during white wine (Vitis vinifera L. cv. ENCRUZADO ageing on lees with stirring in oak wood barrels and in a stainless steel tank with oak staves

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Ana Rodrigues

2012-12-01

Significance and impact of the study: This study is a technological approach of a process largely used by white wine producers who want to market a fresh wine produced with stirring of lees with a woody character. It reports the evolution of mannoproteins through four months of ageing on lees with two different stirring processes that can have a direct impact on the cost of the final product.

Evaluating the performance of the Lee-Carter method and its variants in modelling and forecasting Malaysian mortality

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Zakiyatussariroh, W. H. Wan; Said, Z. Mohammad; Norazan, M. R.

2014-12-01

This study investigated the performance of the Lee-Carter (LC) method and it variants in modeling and forecasting Malaysia mortality. These include the original LC, the Lee-Miller (LM) variant and the Booth-Maindonald-Smith (BMS) variant. These methods were evaluated using Malaysia's mortality data which was measured based on age specific death rates (ASDR) for 1971 to 2009 for overall population while those for 1980-2009 were used in separate models for male and female population. The performance of the variants has been examined in term of the goodness of fit of the models and forecasting accuracy. Comparison was made based on several criteria namely, mean square error (MSE), root mean square error (RMSE), mean absolute deviation (MAD) and mean absolute percentage error (MAPE). The results indicate that BMS method was outperformed in in-sample fitting for overall population and when the models were fitted separately for male and female population. However, in the case of out-sample forecast accuracy, BMS method only best when the data were fitted to overall population. When the data were fitted separately for male and female, LCnone performed better for male population and LM method is good for female population.

Determination du niveau d'anticorps antitetaniques en donneurs de sang au moyen du test ELISA-TÉTANOS (São Paulo, SP, Bresil

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Luzia Cristina Contim Ferrato

1990-12-01

Full Text Available Le test ELISA-TÉTANOS (Biosys, France a été utilisé pour le titrage des anti-corps tétaniques (sensibilité = 0,0025 UI/ml en sérums humains de donneurs de sang, 566 hommes et 108 femmes, âges de 18 à 58 ans, moyenne de 29 ans, provenant de São Paulo, SP, Brésil. L'OMS, acceptant seulement la séroneutralisation sur souris (NT, la méthode de référence, pour les études sur la protection contre le tétanos, préconise le titre de 0,01 UI/ml comme minimum protecteur. BOURLEAUD & HUET ont proposé la limite de 0,06 UI/ml quand s'emploie le test ELISA, en attendant à une certaine discordance inévitable entre les méthodes. Parmi les 674 sérums étudiés, 178 (26,41% n'ont pas présenté d'anticorps ( 0,06 UI/ml.

W3C director Tim Berners-Lee to be Knighted by Queen Elizabeth web inventor recognized for contributions to internet development

CERN Document Server

2003-01-01

"Tim Berners-Lee, the inventor of the World Wide Web and director of the World Wide Web Consortium (W3C), will be made a Knight Commander, Order of the British Empire (KBE) by Queen Elizabeth" (1/2 page).

Extracorporeal irradiation of calves blood. Effects on: the lymphocytes, the blood-platelet function, seric proteins, and fibrinogen; Irradiation extracorporelle du sang de veau effets sur: les lymphocytes, la fonction plaquettaire, les proteines seriques et le fibrinogene

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Hollard, D; Suscillon, M; Benabid, Y; Concord, E; Ivanoff, M; Laurent, M; Rambaud, F [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

1969-07-01

The present paper reports the results obtained after extracorporeal irradiation of circulating blood of calves. Animals are divided in 3 groups as follows: - control animals: blood circulation without irradiation; - calves which received 40000 rads during 24 hours of continuous irradiation; - calves which received the same dose, during a period of 5 days (5 hours every day). The more interesting results are: - the early lymphopenia which persists for 7 or 8 weeks and may be in relationship with the change of immunoglobulins; - a constant hyperfibrinemia (12 g/l) never reported, as far as we know, by authors using I.E.C. Several hypothesis are advanced to explain this phenomenon. (authors) [French] Ce travail presente l'ensemble des resultats hematologiques obtenus apres irradiation extracorporelle du sang de veaux repartis en 3 series: - veaux temoins: circulation du sang sans irradiation - veaux soumis a une irradiation continue dose globale integree de 40000 rads en 24 heures; - veaux ayant recu la meme dose globale en irradiation fractionnee repartie sur 5 jours (5 heures par jour). Les resultats les plus marquants sont d'une part une lymphopenie precoce se prolongeant durant 7 a 8 semaines et qui pourrait etre reliee aux modifications observees sur les immunoglobulines. D'autre part une hyperfibrinemie (12 g/l) constante, apparemment jamais signalee par d'autres auteurs utilisant l'I.E.C. Plusieurs hypotheses explicatives de ce phenomene sont exposees et sont a l'etude. (auteurs)

Extracorporeal irradiation of calves blood. Effects on: the lymphocytes, the blood-platelet function, seric proteins, and fibrinogen; Irradiation extracorporelle du sang de veau effets sur: les lymphocytes, la fonction plaquettaire, les proteines seriques et le fibrinogene

Energy Technology Data Exchange (ETDEWEB)

Hollard, D.; Suscillon, M.; Benabid, Y.; Concord, E.; Ivanoff, M.; Laurent, M.; Rambaud, F. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

1969-07-01

The present paper reports the results obtained after extracorporeal irradiation of circulating blood of calves. Animals are divided in 3 groups as follows: - control animals: blood circulation without irradiation; - calves which received 40000 rads during 24 hours of continuous irradiation; - calves which received the same dose, during a period of 5 days (5 hours every day). The more interesting results are: - the early lymphopenia which persists for 7 or 8 weeks and may be in relationship with the change of immunoglobulins; - a constant hyperfibrinemia (12 g/l) never reported, as far as we know, by authors using I.E.C. Several hypothesis are advanced to explain this phenomenon. (authors) [French] Ce travail presente l'ensemble des resultats hematologiques obtenus apres irradiation extracorporelle du sang de veaux repartis en 3 series: - veaux temoins: circulation du sang sans irradiation - veaux soumis a une irradiation continue dose globale integree de 40000 rads en 24 heures; - veaux ayant recu la meme dose globale en irradiation fractionnee repartie sur 5 jours (5 heures par jour). Les resultats les plus marquants sont d'une part une lymphopenie precoce se prolongeant durant 7 a 8 semaines et qui pourrait etre reliee aux modifications observees sur les immunoglobulines. D'autre part une hyperfibrinemie (12 g/l) constante, apparemment jamais signalee par d'autres auteurs utilisant l'I.E.C. Plusieurs hypotheses explicatives de ce phenomene sont exposees et sont a l'etude. (auteurs)

76 FR 79228 - Combined Licenses at William States Lee III Nuclear Station Site, Units 1 and 2; Duke Energy...

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2011-12-21

... NUCLEAR REGULATORY COMMISSION [Docket Nos. 52-018 and 52-019; NRC-2008-0170] Combined Licenses at William States Lee III Nuclear Station Site, Units 1 and 2; Duke Energy Carolinas, LLC AGENCY: Nuclear.... SUMMARY: Notice is hereby given that the U.S. Nuclear Regulatory Commission (NRC) and the U.S. Army Corps...

Vernon Lee in the Vatican: the uneasy alliance of aestheticism and archaeology.

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Evangelista, Stefano

2009-01-01

From the 1800s onward, aesthetic critics attempted to free the study of ancient Greek art from the frameworks of institutional education and professionalized criticism. In this process, aestheticism entered an uneasy alliance with archaeology, a discipline that was likewise challenging traditional modes of classical learning practiced in public schools and the old universities. In "The Child in the Vatican" (1881), Vernon Lee -- writing under the influence of Pater and from a position of cosmopolitan female amateurism -- examines the uses of archaeological science in the study of classical art. Her analysis of the sculptures of the Niobe Group at once relies on the archaeological method and asks readers to doubt scientific approaches to art that dim the sublime power of the art object.

Kinoshita-Lee-Nauenberg theorem and soft radiation in gauge theories: Abelian case

International Nuclear Information System (INIS)

Akhoury, R.; Sotiropoulos, M.G.; Zakharov, V.I.

1997-01-01

We present a covariant formulation of the Kinoshita-Lee-Nauenberg (KLN) theorem for processes involving the radiation of soft particles. The role of the disconnected diagrams is explored and a rearrangement of the perturbation theory is performed such that the purely disconnected diagrams are factored out. The remaining effect of the disconnected diagrams results in a simple modification of the usual Feynman rules for the S-matrix elements. As an application, we show that, when combined with the Low theorem, this leads to a proof of the absence of the 1/Q corrections to inclusive processes (such as the Drell-Yan process). In this paper the Abelian case is discussed to all orders in the coupling. copyright 1997 The American Physical Society

A Study of Sasin-Animal Sky Map on Chonmunryucho

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Hong-Jin Yang

2003-03-01

Full Text Available Chon-Mun-Ryu-Cho, written (edited by Lee Sun-Ji during the period of King Se-Jong, is a representative astronomy book of Cho-Sun (A.D. 1392 -1910 Dynasty. We find and study in the first page of the book; the description of 28 oriental constellations as a Sasin (four mythical oriental animals-animal sky map which is not widely known yet. The map consists of four groups of constellations, each of which represents the Sasin: Chang-Ryong (dragon, Baek-Ho (tigers with Ki-Rin [Oriental giraffe], Ju-Jak (Chinese phoenix, Hyun-Mu (a tortoise interwined with a snake. Each group (animals spans 2˜7 of 28 oriental constellations As we know from the illustration of the Chon-Sang-Yol-Cha-Bun-Ya-Ji-Do a representative sky map of Cho-Sun Dynasty, astronomy in Cho-Sun Dynasty is closely related to that in Go-Gu-Ryer (B.C. 37 -A.D. 668 Dynasty. Since these Sasin-animals appear in most mural paintings of Go-Gu-Ryer tombs, visualization of sky with these animal constellations could have been established as early as in Go-Gu-Ryer Dynasty. We also reconstruct this ''A Sasin-animal Korean sky map'' based on the shapes of the Sasin and Ki-Rin from Go-Gu-Ryer paintings and 28 oriental constellations in Chon-Sang-Yol-Cha-Bun-Ya-Ji-Do.

Efeitos da Histerectomia Total Abdominal sobre o Fluxo Sangüíneo Ovariano Effect of Total Abdominal Hysterectomy on Ovarian Blood Supply

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Eliana Aguiar Petri Nahás

2002-06-01

Full Text Available Objetivo: avaliar os efeitos da histerectomia total abdominal (HTA sobre o fluxo sangüíneo ovariano, em mulheres no menacme, por meio da dopplervelocimetria e ultra-sonografia transvaginal. Métodos: estudo prospectivo no qual foram incluídas 61 mulheres, com idade igual ou inferior a 40 anos. As pacientes foram divididas em dois grupos: G1, com 31 pacientes submetidas à HTA, e G2, com 30 mulheres normais não submetidas à cirurgia. Somente foram incluídas pacientes eumenorréicas, ovulatórias, não-obesas ou fumantes, sem cirurgias ou doenças ovarianas prévias. Avaliou-se o fluxo sangüíneo das artérias ovarianas, inicialmente e aos 6 e 12 meses, pelo índice de pulsatilidade (IP na dopplervelocimetria, e o volume ovariano pela ultra-sonografia transvaginal (US. Para análise estatística empregou-se teste t pareado, análise de perfil, teste de Friedman e teste de Mann-Whitney. Resultados: na comparação estatística inicial os grupos foram homogêneos quanto às características epidemiológicas e quanto aos demais parâmetros avaliados neste estudo. Nas pacientes submetidas à histerectomia, observaram-se aos 6 e 12 meses aumento do volume ovariano ao US e diminuição do IP avaliado pela dopplervelocimetria (pPurpose: to evaluate the effect of total abdominal hysterectomy on ovarian blood supply in women in reproductive age, using transvaginal color Doppler. Methods: a prospective study was carried out on 61 40-year-old or younger women. They were divided into two groups: G1, 31 patients submitted to hysterectomy, and G2, 30 normal women. Criteria of inclusion: normal ovarian function at baseline, normal body weight, without expasure to tobacco, no history of laparotomy or ovarian pathology. The pulsatility index (PI of ovarian arteries determined by Doppler and the transvaginal ultrasonographic measurement of the ovarian volume were performed at three moments: baseline, 6 and 12 months. Results: at baseline the groups were

The Effects of Input Enhancement on Grammar Learning and Comprehension: A Modified Replication of Lee (2007) with Eye-Movement Data

Science.gov (United States)

Winke, Paula M.

2013-01-01

In his 2007 study "Effects of Textual Enhancement and Topic Familiarity on Korean EFL Students' Reading Comprehension and Learning of Passive Form," Lee demonstrated that learners were better able to correct written sentences that contained incorrect English passive forms after exposure to texts flooded with enhanced (versus…

Comparative study on medical utilization and costs of chronic obstructive pulmonary disease with good lung function

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Lim JU

2017-09-01

Full Text Available Jeong Uk Lim,1 Kyungjoo Kim,2 Sang Hyun Kim,3 Myung Goo Lee,4 Sang Yeub Lee,5 Kwang Ha Yoo,6 Sang Haak Lee,1 Ki-Suck Jung,7 Chin Kook Rhee,2 Yong Il Hwang7 1Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, St Paul’s Hospital, 2Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, 3Big Data Division, Health Insurance Review and Assessment Service, Wonju, 4Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, 5Department of Internal Medicine, Korea University, Anam Hospital, 6Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, 7Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Hallym University College of Medicine, Anyang, Republic of Korea Introduction: Patients with mild to moderate chronic obstructive pulmonary disease (COPD are underdiagnosed and undertreated due to the asymptomatic nature of the disease. Previous studies on patients with mild COPD have focused on symptomatic patients. Therefore, in this study, we evaluated the treatment status of patients with early COPD in Korea.Materials and methods: We compared hospital visits, medical costs per person, and COPD medication use by patients with COPD screened from the general population and COPD cohort patients. Patients with COPD aged ≥40 years with the value of forced expiratory volume in 1 s (FEV1 ≥60% were selected from the 2007 to 2012 Korea National Health and Nutrition Examination Survey (KNHANES data. Data including the number of outpatient clinic visits, admission to hospitals, COPD-related medications, and medical

Brown trout in the Lees Ferry reach of the Colorado River—Evaluation of causal hypotheses and potential interventions

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Runge, Michael C.; Yackulic, Charles B.; Bair, Lucas S.; Kennedy, Theodore A.; Valdez, Richard A.; Ellsworth, Craig; Kershner, Jeffrey L.; Rogers, R. Scott; Trammell, Melissa A.; Young, Kirk L.

2018-04-17

Over the period 2014–2016, the number of nonnative brown trout (Salmo trutta) captured during routine monitoring in the Lees Ferry reach of the Colorado River, downstream of Glen Canyon Dam, began increasing. Management agencies and stakeholders have questioned whether the increase in brown trout in the Lees Ferry reach represents a threat to the endangered humpback chub (Gila cypha), to the rainbow trout (Oncorhynchus mykiss) sport fishery, or to other resources of concern. In this report, we evaluate the evidence for the expansion of brown trout in the Lees Ferry reach, consider a range of causal hypotheses for this expansion, examine the likely efficacy of several potential management interventions to reduce brown trout, and analyze the effects of those interventions on other resources of concern.The brown trout population at Lees Ferry historically consisted of a small number of large fish supported by low levels of immigration from downstream reaches. This population is now showing signs of sustained successful reproduction and is on the cusp of recruiting locally hatched fish into the spawning class, based on analysis with a new integrated population model. The proximate causes of this change in status are a large pulse of immigration in the fall of 2014 and higher reproductive rates in 2015–2017. The ultimate causes of this change are not clear. The pulse of immigrants from downstream reaches in fall 2014 may have been induced by three sequential high-flow releases from the dam in November of 2012–2014, but may also have been the result of a unique set of circumstances unrelated to dam operations. The increase in reproduction may have been the result of any number of changes, including an Allee effect, warmer water temperatures, a decrease in competition from rainbow trout, or fall high-flow releases. Correlations over space and time among predictor variables do not allow us to make a clear inference about the cause of the changes. Under a null causal

Séroprévalence des marqueurs viraux sur les dons du sang au Centre de Transfusion Sanguine, Hôpital Militaire d’Instruction Mohammed V de Rabat

Science.gov (United States)

Uwingabiye, Jean; Zahid, Hafidi; Unyendje, Loubet; Hadef, Rachid

2016-01-01

Le but de ce travail était de déterminer la prévalence du virus de l’immunodéficience humaine (VIH), du virus de l’hépatite B (VHB) et C (VHC) sur les dons du sang collectés au Centre de transfusion sanguine(CTS) de l’hôpital militaire d’instruction Mohammed V entre 2010 et 2012. Etude rétrospective menée auprès des donneurs de sang militaires âgés de 18 à 50 ans avec prédominance masculine (95%). L’entretien médical pré-don constitue la première barrière de sélection des sujets à risque. Le dépistage biologique était réalisé par technique immuno-enzymatique en milieu liquide utilisant des anticorps et/ou des antigènes. L’ELISA (enzyme linked immuno-sorbent assay) combiné de quatrième génération pour VHC et VIH a été utilisé. La confirmation a été faite en réalisant la même technique en double au CTS et au laboratoire de virologie. Dans notre série de 25661 échantillons testés, la prévalence du VHB était 3,97‰ (n=102), celle de VHC était 2,45 ‰ (n=63), celle de VIH était 0,15 ‰ (n=4). Un seul cas de coïnfection (0,039 ‰) par le VHB et VHC a été noté, aucune association entre VIH-VHB, VIH-VHC ou VHB, VHC et VIH n’a été enregistrée. Les taux faibles de séroprévalence des marqueurs viraux de notre étude montrent l’amélioration des mesures préventives en ce qui concerne la sélection des donneurs et des tests de dépistage. Cette prévalence constatée incite à maintenir l’utilisation du réactif combiné qui est la seule alternative à la biologie moléculaire pour les pays en voie de développement. PMID:28292147

Pyrite-coated granite cobbles at Lee Bay, Stewart Island

International Nuclear Information System (INIS)

Brathwaite, R.L.; Skinner, D.N.B.; Faure, K.; Edwards, E.

2014-01-01

On the west side of Lee Bay on the northeast coast of Stewart Island, ventifact cobbles of pyrite-coated granite occur on the beach near the high tide mark and appear to be derived from a sand-cemented gravel deposit that forms a low bank at the back of the beach. The pyrite coat (up to 1 mm thick) completely covers the granitic cobbles and is zoned, with an inner zone of fine-grained colloform pyrite and an outer framboidal zone. Framboidal pyrite is typically formed in anoxic sedimentary environments. Subrounded grains of hematite, ilmenite with hematite blebs, magnetite, feldspar, biotite, quartz and zircon are present in the outer framboidal zone, with some ilmenite and hematite grains being partially replaced by pyrite. The assemblage of ilmenite-hematite-magnetite-biotite-zircon is similar both in mineralogy and size range to that found in heavy mineral beach sands. Sulphur isotope values of the pyrite coat are consistent with formation of the pyrite by microbial sulphate reduction of seawater sulphate. The framboidal texture together with the presence of grains of beach sand in the pyrite coating indicate that it was deposited in a low-temperature sedimentary environment. (author)

Generalized Lee-Wick formulation from higher derivative field theories

International Nuclear Information System (INIS)

Cho, Inyong; Kwon, O-Kab

2010-01-01

We study a higher derivative (HD) field theory with an arbitrary order of derivative for a real scalar field. The degree of freedom for the HD field can be converted to multiple fields with canonical kinetic terms up to the overall sign. The Lagrangian describing the dynamics of the multiple fields is known as the Lee-Wick (LW) form. The first step to obtain the LW form for a given HD Lagrangian is to find an auxiliary field (AF) Lagrangian which is equivalent to the original HD Lagrangian up to the quantum level. Until now, the AF Lagrangian has been studied only for N=2 and 3 cases, where N is the number of poles of the two-point function of the HD scalar field. We construct the AF Lagrangian for arbitrary N. By the linear combinations of AF fields, we also obtain the corresponding LW form. We find the explicit mapping matrices among the HD fields, the AF fields, and the LW fields. As an exercise of our construction, we calculate the relations among parameters and mapping matrices for N=2, 3, and 4 cases.

Q & A with Ed Tech Leaders: Interview with Curtis J. Bonk, Mimi Miyoung Lee, Thomas C. Reeves, & Thomas H. Reynolds

Science.gov (United States)

Viner, Mark; Gardner, Ellen; Shaughnessy, Michael F.

2016-01-01

Curtis J. Bonk, is Professor of Instructional Systems Technology at Indiana University and President of CourseShare. Mimi Miyoung Lee is Associate Professor in the Department of Curriculum and instruction at the University of Houston. Thomas C. Reeves is Professor Emeritus of Learning, Design, and Technology at the University of Georgia. Thomas H.…

Nobelist TD LEE Scientist Cooperation Network and Scientist Innovation Ability Model

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Jin-Qing Fang

2013-01-01

Full Text Available Nobelist TD Lee scientist cooperation network (TDLSCN and their innovation ability are studied. It is found that the TDLSCN not only has the common topological properties both of scale-free and small-world for a general scientist cooperation networks, but also appears the creation multiple-peak phenomenon for number of published paper with year evolution, which become Nobelist TD Lee’s significant mark distinguished from other scientists. This new phenomenon has not been revealed in the scientist cooperation networks before. To demonstrate and explain this new finding, we propose a theoretical model for a nature scientist and his/her team innovation ability. The theoretical results are consistent with the empirical studies very well. This research demonstrates that the model has a certain universality and can be extended to estimate innovation ability for any nature scientist and his/her team. It is a better method for evaluating scientist innovation ability and his/her team for the academic profession and is of application potential.

Application of ultrasound to improve lees ageing processes in red wines.

Science.gov (United States)

Del Fresno, Juan Manuel; Loira, Iris; Morata, Antonio; González, Carmen; Suárez-Lepe, Jose Antonio; Cuerda, Rafael

2018-09-30

Ageing on lees (AOL) is a technique that increases volatile compounds, promotes colour stability, improves mouthfeel and reduces astringency in red wines. The main drawback is that it is a slow process. Several months are necessary to obtain perceptible effects in wines. Different authors have studied the application of new techniques to accelerate the AOL process. Ultrasound (US) has been used to improve different food industry processes; it could be interesting to accelerate the yeast autolysis during AOL. This work evaluates the use of the US technique together with AOL and oak chips for this purpose studying the effects of different oenological parameters of red wines. The results obtained indicate an increase of polysaccharides content when US is applied in wine AOL. In addition, total polyphenol index (TPI) and volatile acidity were not affected. However, this treatment increases the dissolved oxygen affecting the volatile compounds and total anthocyanins. Copyright © 2018 Elsevier Ltd. All rights reserved.

Looking Forward: Texas and Its Elderly. Highlights of the Robert Lee Sutherland Seminar (4th, Austin, Texas, May 12, 1984).

Science.gov (United States)

Coleman, Marion Tolbert, Ed.; And Others

This document presents the program agenda and highlights from the one-day Robert Lee Sutherland Seminar held to examine the current status and the future of the elderly population of Texas. Included is the speech, "The Longevity Revolution" by Robert N. Butler, in which is discussed the gain in life expectancy, the feminization of aging,…

Electromagnetic and Scalar Pion form factor in the Kroll-Lee-Zumino model

International Nuclear Information System (INIS)

Dominguez, C.A.; Jottar, J.I.; Loewe, M.; Willers, B.

2009-01-01

The renormalizable Abelian quantum field theory model of Kroll, Lee, and Zumino is used at the one loop level to compute vertex corrections to the tree-level, Vector Meson Dominance (VMD) electromagnetic pion form factor. These corrections, together with the one-loop vacuum polarization contribution, imply a resulting electromagnetic pion form factor in excellent agreement with data in the whole range of accessible momentum transfers in the space-like region. The time-like form factor, which reproduces the Gounaris-Sakurai formula at and near the rho-meson peak, is unaffected by the vertex correction at order O(g 2 ). The KLZ model is also used to compute the scalar radius of the pion at the one loop level, finding π 2 > S =0.40fm 2 . This value implies for the low energy constant of chiral perturbation theory l-bar 4 =3.4

Concentrações sangüíneas de lactato em eqüinos durante a prova de fundo do concurso completo de equitação

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Gomide Lina Maria Wehrle

2006-01-01

Full Text Available Colheu-se sangue de 13 eqüinos competindo na prova de Fundo do Concurso Completo de Equitação, categoria internacional três estrelas, e dosou-se lactato sangüíneo na manhã antes da prova, antes e imediatamente depois das fases B e D e 10 minutos após a fase D. Foi observado aumento significativo nas concentrações de lactato apenas após o término da fase D, demonstrando que os animais foram submetidos a um grande esforço físico, com desenvolvimento de acidose metabólica decorrente do acúmulo de lactato. Houve diminuição significativa dos valores dez minutos após o término do cross-country, exceto para o eqüino de número 12, único animal a completar o percurso dentro do tempo estipulado, o qual apresentou sinais clínicos de exaustão.

On Dallas Smythe’s “Audience Commodity”: An Interview with Lee McGuigan and Vincent Manzerolle

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Henry Adam Svec

2015-07-01

Full Text Available This interview with Lee McGuigan and Vincent Manzerolle explores some concepts and debates charted by their new co-edited book, The Audience Commodity in a Digital Age: Revisiting a Critical Theory of Commercial Media, which both celebrates and scrutinizes Dallas Smythe’s canonical 1977 essay, “Communications: Blindspot of Western Marxism”. The discussion covers Smythe’s contribution to the field of media studies and the state of current debates pertaining to the theory of the audience commodity, and it also touches on questions of Smythe’s mainstream reception and legacy.

Anormalidades de fluxo sangüíneo cerebral em indivíduos dependentes de cocaína Cerebral blood flow abnormalities in cocaine dependent subjects

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Sergio Nicastri

2000-06-01

Full Text Available INTRODUÇÃO: Nos últimos anos, tem havido relatos de anormalidades do fluxo sanguíneo cerebral em indivíduos com o abuso de cocaína, detectadas por meio de tomografia computadorizada por emissão de fóton único (SPECT. Esse padrão anormal de perfusão cerebral tem sido associado a prejuízos cognitivos mas não a alterações observáveis por meio de exames de neuroimagem estrutural. Um problema envolvendo a maioria dos trabalhos publicados sobre esse tema é a inclusão de um grande número de usuários de heroína nas amostras estudadas. Essa outra droga também parece afetar o padrão de perfusão cerebral, particularmente durante estados de abstinência. MÉTODOS: Quatorze pacientes dependentes de cocaína (nenhum com uso de opióides e 14 voluntários normais (grupo controle foram submetidos a exames de SPECT com dímero de etil-cisteína marcado com tecnécio-99m. A análise dos exames de SPECT foi realizada por meio de análise visual qualitativa das imagens obtidas (procedimento padrão na prática clínica, realizada por um radiologista não informado sobre o diagnóstico dos indivíduos avaliados. RESULTADOS: A análise visual revelou um padrão sugestivo de irregularidades do fluxo sangüíneo cerebral em nove pacientes, mas em apenas dois controles (p = 0,018; teste exato de Fisher bicaudal. CONCLUSÕES: Anormalidades de circulação cerebral podem ter relação com prejuízos cognitivos relatados em populações de dependentes de cocaína. Embora déficits de perfusão cerebral associados ao uso de cocaína possam ser irreversíveis, têm surgido relatos na literatura de tratamentos para essas anormalidades de fluxo sangüíneo. Alterações de fluxo sangüíneo cerebral associadas à dependência de cocaína ocorrem mesmo na ausência de abuso ou dependência de opióides.INTRODUCTION: In the last years, there have been reports of abnormalities in brain blood flow of cocaine abusers, detected by single photon computed

Details of the general numerical solutions of the Friedberg-Lee soliton model for ground and exited states

International Nuclear Information System (INIS)

Koeppel, T.; Harvey, M.

1984-06-01

A new numerical method is applied to solving the equations of motion of the Friedberg-Lee Soliton model for both ground and spherically symmetric excited states. General results have been obtained over a wide range of parameters. Critical coupling constants and critical particle numbers have been determined below which soliton solutions cease to exist. The static properties of the proton are considered to show that as presently formulated the model fails to fit all experimental data for any set of parameters

Further Clarification on the Hom, Mitchell, Lee, and Griffeth (2012) Model: Reply to Bergman, Payne, and Boswell (2012) and Maertz (2012)

Science.gov (United States)

Griffeth, Rodger W.; Lee, Thomas W.; Mitchell, Terence R.; Hom, Peter W.

2012-01-01

In this article, we reply to Bergman, Payne, and Boswell (2012) and Maertz (2012), who commented on our reconceptualization of the employee turnover criterion and proximal withdrawal states (Hom, Mitchell, Lee, & Griffeth, 2012). We agree with some points (e.g., anticipated destinations) but take issue with others (e.g., turnover intentions as…

Samuel Holden Parsons Lee (1772-1863): American physician, entrepreneur and selfless fighter of the 1798 Yellow Fever epidemic of New London, Connecticut.

Science.gov (United States)

Mattie, James K; Desai, Sukumar P

2015-02-01

Samuel Holden Parsons Lee practised medicine at a time when the germ theory of disease had not yet been proposed and antibiotics remained undiscovered. In 1798 he served selflessly as the only physician in town who was willing to battle the Yellow Fever outbreak of New London, Connecticut. Because he practised at the dawn of the age of patent medicine, unfortunately his name also came to be associated with medical quackery. We argue that his contributions have been grossly underestimated. He compounded and vended medications - including bilious pills and bitters - that were gold standards of the day. Moreover, one preparation for treatment of kidney stones led to his sub-specialization in this field and was met with such success that its sale continued for nearly 100 years after his death. While a talented medical man, Lee also had a knack for business, finding success in trading, whaling and real estate. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

Comparison of total polyphenols content and antioxidant potential of wines from ‘Welschriesling’ and ‘Sauvignon Blanc’ varieties during ageing on fine lees

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Jasna Lužar

2016-10-01

Full Text Available Phenolic compounds are key components of wine, since they contribute to wine characteristics such as colour, astringency and bitterness. They also act like antioxidants, with mechanisms involving free-radical scavenging that could prevent cardiovascular diseases and cancer. The aim of the present work was to compare the obtained results of total polyphenols content and antioxidant potential (AOP of several white wines (welschriesling and sauvignon blanc during ageing on fine lees. The total polyphenols content decreased in average for 16.1 % in welschriesling wines and for 18.7 % in sauvignon blanc wines in the period of three months of wine ageing on lees. In the same period AOP of wines decreased in average for 16.0 % in welschriesling wines and for 8.0 % in sauvignon blanc wines. Expectedly, the samples with added oak chips in grape must had higher antioxidant potential than others.

In the spotlight. Interview with Kenneth Lee, Health Economist, University of Leeds, U.K.. Interview by Johannes Stoelwinder.

Science.gov (United States)

Lee, K

1984-01-01

Ken Lee appointed to the staff of the Nuffield Centre, University of Leeds, as Lecturer in Health Economics in 1970. He is now Senior Lecturer and Director of the Master's Programme in Health Service Studies. His main teaching interests are in health planning and health economics, and he has carried out research and written extensively on approaches to health economics, health planning and management, care of the elderly, primary health care, health financing, and emergency health services.

Lee-Carter state space modeling: Application to the Malaysia mortality data

Science.gov (United States)

Zakiyatussariroh, W. H. Wan; Said, Z. Mohammad; Norazan, M. R.

2014-06-01

This article presents an approach that formalizes the Lee-Carter (LC) model as a state space model. Maximum likelihood through Expectation-Maximum (EM) algorithm was used to estimate the model. The methodology is applied to Malaysia's total population mortality data. Malaysia's mortality data was modeled based on age specific death rates (ASDR) data from 1971-2009. The fitted ASDR are compared to the actual observed values. However, results from the comparison of the fitted and actual values between LC-SS model and the original LC model shows that the fitted values from the LC-SS model and original LC model are quite close. In addition, there is not much difference between the value of root mean squared error (RMSE) and Akaike information criteria (AIC) from both models. The LC-SS model estimated for this study can be extended for forecasting ASDR in Malaysia. Then, accuracy of the LC-SS compared to the original LC can be further examined by verifying the forecasting power using out-of-sample comparison.

The administration of long-term high-fat diet in ovariectomized wistar rat (Study on Daily Food Intake, Lee Index, Abdominal Fat Mass and Leptin Serum Levels

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Dita Fitriani

2016-12-01

Conclusion: Serum leptin levels positively correlated with Lee index and abdominal fat mass, but negatively correlated with daily food intake. Administration of long-term high-fat diet in this study cannot induce leptin resistance.

Interpretation for ''high''-Tc of the totally interconnected solution of the Ma and Lee model

International Nuclear Information System (INIS)

Wiecko, C.

1988-09-01

The already presented totally interconnected (mean-field) approximation of the Ma and Lee model, pictures very well many ingredients of the present status of comprehension of high-T c superconductors. The picture is that of a disordered grain with variable number of particles available for an attractive on-site pairing interaction, embedded in a reservoir of normal particles which fix the chemical potential. Interesting effect of absence of T c and then a sharp increase and slow decay of T c with disorder appears for weak coupling pairing as compared with the hopping probability for single particles. Interpretation is given in terms of one-particle Anderson localization theory and standard mechanisms. (author). 13 refs, 4 figs

Use of transient elastography to predict de novo recurrence after radiofrequency ablation for hepatocellular carcinoma

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Lee SH

2015-02-01

Full Text Available Sang Hoon Lee,1 Seung Up Kim,1–3 Jeong Won Jang,4 Si Hyun Bae,4 Sanghun Lee,1,3 Beom Kyung Kim,1–3 Jun Yong Park,1–3 Do Young Kim,1–3 Sang Hoon Ahn,1–3 Kwang–Hyub Han1–31Department of Internal Medicine, 2Institute of Gastroenterology, Yonsei University College of Medicine, 3Liver Cirrhosis Clinical Research Center, 4Department of Internal Medicine, College of Medicine, Catholic University of Korea, Seoul, KoreaBackground/purpose: Liver stiffness (LS measurement using transient elastography can accurately assess the degree of liver fibrosis, which is associated with the risk of the development of hepatocellular carcinoma (HCC. We investigated whether LS values could predict HCC de novo recurrence after radiofrequency ablation (RFA.Methods: This retrospective, multicenter study analyzed 111 patients with HCC who underwent RFA and LS measurement using transient elastography between May 2005 and April 2011. All patients were followed until March 2013 to monitor for HCC recurrence.Results: This study included 76 men and 35 women with a mean age of 62.4 years, and the mean LS value was 21.2 kPa. During the follow-up period (median 22.4 months, 47 (42.3% patients experienced HCC de novo recurrence, and 18 (16.2% died. Patients with recurrence had significantly more frequent liver cirrhosis, more frequent history of previous treatment for HCC, higher total bilirubin, larger spleen size, larger total tumor size, higher tumor number, higher LS values, and lower platelet counts than those without recurrence (all P<0.05. On multivariate analysis, together with previous anti-HCC treatment history, patients with LS values >13.0 kPa were at significantly greater risk for recurrence after RFA, with a hazard ratio (HR of 3.115 (95% confidence interval [CI], 1.238–7.842, P<0.05. Moreover, LS values independently predicted the mortality after RFA, with a HR of 9.834 (95% CI, 1.148–84.211, P<0.05, together with total bilirubin.Conclusions: Our

Valence-associated uranium isotope fractionation of uranium enriched phosphate in a shallow aquifer, Lee County, Florida

International Nuclear Information System (INIS)

Weinberg, J.M.; Levine, B.R.; Cowart, J.B.

1993-01-01

The source of anomalously high concentrations of uranium, characterized by U-234/U-238 activity ratios significantly less than unity, in shallow groundwaters of Lee County, Florida, was investigated. Uranium in cores samples was separated into U(IV) and U(VI) oxidation state fractions, and uranium analyses were conducted by alpha spectrometry. Uranium mobility was also studied in selected leaching experiments. Results indicate that mobilization of unusually soluble uranium, present in uranium enriched phosphate of the Pliocene age Tamiami Formation at determined concentrations of up to 729 ppm, is the source for high uranium concentrations in groundwater. In leaching experiments, approximately one-third of the uranium present in the uranium enriched phosphate was mobilized into the aqueous phase. Results of previous investigations suggest that U-234, produced in rock by U-238 decay, is selectively oxidized to U(VI). The uranium enriched phosphate studied in this investigation is characterized by selective reduction of U-234, with a pattern of increasing isotopic fractionation with core depth. As a consequence, U-234/U-238 activity ratios greater than 1.0 in the U(IV) fraction, and less than 1.0 in the U(VI) fraction have developed in the rock phase. In leaching experiments, the U(VI) fraction from the rock was preferentially mobilized into the aqueous phase, suggesting that U-234/U-238 activity ratios of leaching groundwaters are strongly influenced by the isotopic characteristics of the U(VI) fraction of rock. It is suggested that preferential leaching of U(VI), present in selectivity reduced uranium enriched phosphate, is the source for low activity ratio groundwaters in Lee County

Trajectory phase transitions and dynamical Lee-Yang zeros of the Glauber-Ising chain.

Science.gov (United States)

Hickey, James M; Flindt, Christian; Garrahan, Juan P

2013-07-01

We examine the generating function of the time-integrated energy for the one-dimensional Glauber-Ising model. At long times, the generating function takes on a large-deviation form and the associated cumulant generating function has singularities corresponding to continuous trajectory (or "space-time") phase transitions between paramagnetic trajectories and ferromagnetically or antiferromagnetically ordered trajectories. In the thermodynamic limit, the singularities make up a whole curve of critical points in the complex plane of the counting field. We evaluate analytically the generating function by mapping the generator of the biased dynamics to a non-Hermitian Hamiltonian of an associated quantum spin chain. We relate the trajectory phase transitions to the high-order cumulants of the time-integrated energy which we use to extract the dynamical Lee-Yang zeros of the generating function. This approach offers the possibility to detect continuous trajectory phase transitions from the finite-time behavior of measurable quantities.

Associação entre pressão sangüínea com sinais e sintomas de dor orofacial e disfunção temporomandibular = Relationship between blood pressure with signs and symptons of orofacial pain and temporomandibular disorders

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Haesbaert, Bibiana M.

2005-01-01

Full Text Available O objetivo deste estudo é o de determinar a função da pressão sangüínea como possível fator diagnóstico em pacientes com desordens temporomandibulares (DTM. Foram examinadas as pressões sanguíneas de mulheres entre 17 e 40 anos de idade, com sinais e sintomas de desordens temporomandibulares (DTM, versus grupo controle (sem DTM, usando o aparelho “Digital Blood Pressure Meter” da A&D Engineering, Inc. Sendo assim, observou-se uma tendência à hipotensão nos pacientes com DTM em relação ao grupo controle

Origin of the waves in ‘A case-study of mesoscale spectra of wind and temperature, observed and simulated’: Lee waves from the Norwegian mountains

DEFF Research Database (Denmark)

Larsén, Xiaoli Guo; Larsen, Søren Ejling; Hahmann, Andrea N.

2012-01-01

their initiation and ending, propagation, spatial orientation and wavelength, are consistent among the different data sources. This evidence and the key wave parameters derived from the WRF simulation, including the Scorer parameter and wave tilt, all suggest that the waves are lee waves generated by uplift from...

Solutions of simple dual bootstrap models satisfying Lee--Veneziano relation and the smallness of cut discontinuities

International Nuclear Information System (INIS)

Chiu, C.B.; Hossain, M.; Tow, D.M.

1977-07-01

To investigate the t-dependent solutions of simple dual bootstrap models, two general formulations are discussed, one without and one with cut cancellation at the planar level. The possible corresponding production mechanisms are discussed. In contrast to Bishari's formulation, both models recover the Lee-Veneziano relation, i.e., in the peak approximation the Pomeron intercept is unity. The solutions based on an exponential form for the reduced triple-Reggeon vertex for both models are discussed in detail. Also calculated are the cut discontinuities for both models and for Bishari's and it is shown that at both the planar and cylinder levels they are small compared with the corresponding pole residues. Precocious asymptotic planarity is also found in the solutions

LEE SHULMAN: CONTRIBUIÇÕES PARA A INVESTIGAÇÃO DA FORMAÇÃO DOCENTE EM ENFERMAGEM E SAÚDE

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Vânia Marli Schubert Backes

2017-01-01

Full Text Available Objetivo : reflexionar sobre los constructos de conocimiento básico para la enseñanza, fuentes de este conocimiento y el modelo de acción y raciocinio pedagógico de Shulman con miras a la investigación de la formación docente en enfermería y salud. Método : se trata de reflexión articulada en tres secciones: Sobre Lee Shulman; Fuentes y conocimiento básico para la enseñanza; Modelo de acción y raciocinio pedagógico. Resultados: Lee Shulman es un investigador norteamericano, profesor emérito de la Universidad de Standford, y en el artículo titulado Knowledge and teaching: foundations of the new reform, publicado originalmente en 1987, presentó tres constructos para la comprensión e investigación de la práctica docente, que influye desde entonces a investigadores de diversas áreas del conocimiento, como biología, matemáticas, lengua inglesa, música y ciencias sociales, ahora utilizados e insertados también en la investigación en enfermería y salud. Conclusión : se presentaron los constructos, concluyendo que su utilización en la investigación puede contribuir tanto al análisis de la formación y de la práctica docente.

Sistema de grupo sangüíneo Duffy: biologia e prática transfusional Duffy blood group system: biology and transfusion practice

Directory of Open Access Journals (Sweden)

Eduardo Jens

2005-06-01

Full Text Available Após a introdução da técnica de antiglobulina indireta por Coombs em meados da década de 40, vários anticorpos antieritrocitários foram descobertos. O grupo sanguíneo Duffy foi descoberto quando Cutbush e Ikin detectaram, no início da década de 50, os primeiros anticorpos desse sistema. Os anticorpos Duffy são clinicamente significantes na prática transfusional, pois mostraram ser causadores de reação hemolítica transfusional e de doença hemolítica do recém-nascido, sendo de ocorrência mundial. O gene FY é constituído por dois exons e seu lócus foi mapeado no cromossomo 1q22-q23. Os antígenos Fyª e Fy b são codificados pelos alelos FYA e FYB e são responsáveis pelos fenótipos Fy(a+b-, Fy(a-b+ e Fy(a+b+. São carreados por uma glicoproteína de 336 aminoácidos também chamada DARC (Duffy Antigen/Receptor for Chemokines, que tem alta afinidade a quimiocinas, sendo também os receptores para Plasmodium vivax. Os polimorfismos relacionados aos seus alelos permitiram o desenvolvimento da técnica de genotipagem por PCR, que é de grande utilidade para a segurança transfusional e incompatibilidade feto-materna. Na última década, inúmeras pesquisas têm sido feitas quanto ao papel biológico dos antígenos de grupos sangüíneos. Nesse artigo iremos revisar o sistema de grupo sangüíneo Duffy, em especial quanto à prática transfusional e suas funções biológicas.After the introduction of the indirect antiglobulin technique by Coombs in the middle of the 1940's, several antibodies have been discovered. Duffy blood group system came to light when Cutbush and Ikin detected the first antibodies related to this system in the beginning of the 1950's. The antibodies of this system are clinically significant in transfusional practice as they have been involved in hemolytic transfusion reactions and hemolytic disease of the newborn, showing them to be of worldwide occurrence. The FY gene is constituted of two exons and its

Size variation and collapse of emphysema holes at inspiration and expiration CT scan: evaluation with modified length scale method and image co-registration

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Oh SY

2017-07-01

Full Text Available Sang Young Oh,1,* Minho Lee,1,* Joon Beom Seo,1,* Namkug Kim,1,2,* Sang Min Lee,1 Jae Seung Lee,3 Yeon Mok Oh3 1Department of Radiology, 2Department of Convergence Medicine, 3Department of Pulmonology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea *These authors contributed equally to this work Abstract: A novel approach of size-based emphysema clustering has been developed, and the size variation and collapse of holes in emphysema clusters are evaluated at inspiratory and expiratory computed tomography (CT. Thirty patients were visually evaluated for the size-based emphysema clustering technique and a total of 72 patients were evaluated for analyzing collapse of the emphysema hole in this study. A new approach for the size differentiation of emphysema holes was developed using the length scale, Gaussian low-pass filtering, and iteration approach. Then, the volumetric CT results of the emphysema patients were analyzed using the new method, and deformable registration was carried out between inspiratory and expiratory CT. Blind visual evaluations of EI by two readers had significant correlations with the classification using the size-based emphysema clustering method (r-values of reader 1: 0.186, 0.890, 0.915, and 0.941; reader 2: 0.540, 0.667, 0.919, and 0.942. The results of collapse of emphysema holes using deformable registration were compared with the pulmonary function test (PFT parameters using the Pearson’s correlation test. The mean extents of low-attenuation area (LAA, E1 (<1.5 mm, E2 (<7 mm, E3 (<15 mm, and E4 (≥15 mm were 25.9%, 3.0%, 11.4%, 7.6%, and 3.9%, respectively, at the inspiratory CT, and 15.3%, 1.4%, 6.9%, 4.3%, and 2.6%, respectively at the expiratory CT. The extents of LAA, E2, E3, and E4 were found to be significantly correlated with the PFT ­parameters (r=−0.53, −0.43, −0.48, and −0.25, with forced expiratory volume in 1 second (FEV1; −0.81, −0.62, −0.75, and

Impact of GOLD groups of chronic pulmonary obstructive disease on surgical complications

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Kim HJ

2016-02-01

Full Text Available Hyung-Jun Kim,1,2 Jinwoo Lee,1,2 Young Sik Park,1,2 Chang-Hoon Lee,1,2 Sang-Min Lee,1,2 Jae-Joon Yim,1,2 Chul-Gyu Yoo,1,2 Young Whan Kim,1,2 Sung Koo Han,1,2 Sun Mi Choi1,2 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; 2Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea Purpose: Chronic obstructive pulmonary disease (COPD is associated with increased postoperative complications. Recently, the Global Initiative for Chronic Obstructive Lung Disease (GOLD classified COPD patients into four groups based on spirometry results and the severity of symptoms. The objective of this study was to evaluate the impact of GOLD groups on postoperative complications. Patients and methods: We reviewed the medical records of COPD patients who underwent preoperative spirometry between April and August 2013 at a tertiary hospital in Korea. We divided the patients into GOLD groups according to the results of spirometry and self-administered questionnaires that assessed the symptom severity and exacerbation history. GOLD groups, demographic characteristics, and operative conditions were analyzed. Results: Among a total of 405 COPD patients, 70 (17.3% patients experienced various postoperative complications, including infection, wound, or pulmonary complications. Thoracic surgery, upper abdominal surgery, general anesthesia, large estimated blood loss during surgery, and longer anesthesia time were significant risk factors for postoperative complications. Patients in high-risk group (GOLD groups C or D had an increased risk of postoperative complications compared to those in low-risk group (GOLD groups A or B. Conclusion: COPD patients in GOLD groups representing a high exacerbation risk have an increased risk of postoperative complications compared to those with low risk. Keywords: chronic obstructive pulmonary

Absolut sang

DEFF Research Database (Denmark)

Parly, Nila Charlotte

En række analytiske gennemgange af de kvindelige hovedpartier i Richard Wagners værker fra "Den flyvende Hollænder" til "Parsifal". Med afsæt i Carl Dahlhaus' og Carolyn Abbates teorier fokuseres der på orkester- og sangstemmernes klanglige og melodiske betydning for værkernes komplekse dramaturg...

Crescimento de Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong (Leguminosae sob diferentes níveis de sombreamento Growth of Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong (Leguminosae under different shading levels

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Ana Lúcia da Silva Lima

2010-03-01

Full Text Available Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. é uma espécie clímax tolerante a sombra, ao passo que Enterolobium contortisiliquum (Vell. Morong. é uma espécie pioneira. O desenvolvimento destas espécies pode refletir a habilidade de adaptação aos diferentes fatores ambientais (luz, água e temperatura no local em que estão crescendo. O suprimento inadequado de um desses fatores pode reduzir o vigor da planta e limitar seu desenvolvimento. O presente trabalho teve como objetivo avaliar os efeitos do nível de sombreamento no crescimento e a concentração de pigmentos fotossintéticos em duas espécies de leguminosas arbóreas, Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong. O experimento foi conduzido no Setor de Olericultura do Centro Universitário Luterano de Ji-Paraná (CEULJI/ULBRA/Rondônia. Durante a formação das mudas, ambas as espécies foram expostas a quatro tratamentos de sombra: 0 % (controle - sol pleno; 30 %; 50 % e 80 %. Cada tratamento foi constituído com três repetições de cada espécie; o delineamento experimental foi inteiramente casualisado. Quatro meses após a semeadura, as seguintes análises foram realizadas: número de folhas, altura da planta, comprimento do sistema radicular, massa seca total e concentração de pigmentos fotossintéticos. O tratamento sob sol pleno afetou negativamente o crescimento de ambas as espécies. As mudas crescidas sob 50% e 80% apresentaram melhor desenvolvimento. Conforme o aumento do sombreamento houve um decréscimo na razão clorofila a/b e um aumento nas concentrações de clorofila total e carotenóides totais.Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. is a clímax shadow tolerant specie and Enterolobium contortisiliquum (Vell. Morong., by the other hand, is considered as a pioneer specie. The development of these species may reflect its adaptation ability to different environmental

Effect of Saccharomyces strains on the quality of red wines aged on lees.

Science.gov (United States)

Loira, I; Vejarano, R; Morata, A; Ricardo-da-Silva, J M; Laureano, O; González, M C; Suárez-Lepe, J A

2013-08-15

Ageing on lees involves ageing the wine in contact with yeast cells after fermentation. If combined with the addition of oak chips, it can soften the wood flavour and increase the aromatic complexity of wine. The aim of the present work is to optimise both ageing techniques through selection of an adequate Saccharomyces cerevisiae strain. The study lasted 6 months and content of polysaccharides, anthocyanins, proanthocyanidins, volatile compounds, colour parameters and sensory analysis, were periodically evaluated. Among the strains tested, G37 showed the highest release of polysaccharides (24.4±5.5 mg l(-1)). Vanillin, syringaldehyde and furfuryl alcohol increased with ageing time in 7VA2 treatment. The wine aged with CTPL14 strain presented fewer monomeric and oligomeric proanthocyanidins (12.4±0.6 and 83.4±8.3 mg l(-1), respectively), and showed the lowest astringency and bitterness sensations. Results show an improvement in the sensory profile of the red wine aged with a combination of these two techniques. Copyright © 2013 Elsevier Ltd. All rights reserved.

Natural oxygenation of Champagne wine during ageing on lees: A metabolomics picture of hormesis.

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Roullier-Gall, Chloé; Witting, Michael; Moritz, Franco; Gil, Ryan B; Goffette, Delphine; Valade, Michel; Schmitt-Kopplin, Philippe; Gougeon, Régis D

2016-07-15

The oxygenation of Champagne wine after 4 and 6 years of aging on lees in bottle was investigated by FTICR-MS and UPLC-Q-TOF-MS. Three levels of permeability were considered for the stoppers, ranging from 0.2 to 1.8 mg/L/year of oxygen transfer rate. Our results confirmed a good repeatability of ultra-high resolution FTICR-MS, both in terms of m/z and coefficient of variation of peak intensities among biological replicates. Vintages appeared to be the most discriminated features, and metabolite annotations suggested that the oldest wines (2006) were characterized by a higher sensitivity towards oxygenation. Within each vintage, the oxygenation mechanisms appeared to be different for low and high ingresses of oxygen, in agreement with the hormesis character of wine oxygenation. In the particular case of single variety wines and for a given level of stopper permeability, our results also showed that variety discrimination could be easily achieved among wines. Copyright © 2016 Elsevier Ltd. All rights reserved.

Why Can't They Keep the Book Longer and Do We Really Need to Charge Fines? Assessing Circulation Policies at the Harold B. Lee Library: A Case Study

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Wilson, Duane

2014-01-01

In response to a charge from the library administration, the Circulation Committee of the Harold B. Lee Library at Brigham Young University designed and implemented a thorough assessment of circulation policies. Using multiple assessment methods including surveys, focus groups, and statistical analysis, the committee determined that the…

Tratamento dos distúrbios da voz na doença de Parkinson: o método Lee Silverman

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Dias Alice Estevo

2003-01-01

Full Text Available Alterações discretas na qualidade da voz e da articulação podem ser observadas em fases relativamente iniciais da doença de Parkinson (DP. As alterações da voz e da fala na DP constituem, em conjunto, o que se denomina disartria hipocinética ou disartrofonia e caracterizam-se por monotonia e redução da intensidade da voz, articulação imprecisa e distúrbios do ritmo. Recentemente, foram relatados resultados favoráveis através de método de tratamento intensivo e dirigido especificamente para o tratamento da voz na DP, denominado Lee Silverman Voice Treatment (LSVT®. O objetivo essencial desse método é aumentar a intensidade vocal através do incremento do esforço fonatório. O presente estudo teve por objetivo a caracterização das anormalidades vocais (qualidade vocal, padrão articulatório e inteligibilidade em um grupo de pacientes com DP e a avaliação da resposta terapêutica obtida pela administração do método Lee Silverman. A comparação dos dados de análise acústica, bem como da análise perceptivo-auditiva nos períodos pré e pós-tratamento mostraram modificações estatisticamente significantes após o tratamento. Embora o padrão articulatório tenha se mantido impreciso, os benefícios obtidos pelo tratamento na melhora da qualidade vocal e, sobretudo, na intensidade vocal favoreceram a qualidade da comunicação oral, reduziram os sintomas negativos e adequaram a qualidade vocal às necessidades pessoais e sociais dos indivíduos.

Mass elevation and lee effects markedly lift the elevational distribution of ground beetles in the Himalaya-Tibet orogen.

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Schmidt, Joachim; Böhner, Jürgen; Brandl, Roland; Opgenoorth, Lars

2017-01-01

Mass elevation and lee effects markedly influence snow lines and tree lines in high mountain systems. However, their impact on other phenomena or groups of organisms has not yet been quantified. Here we quantitatively studied their influence in the Himalaya-Tibet orogen on the distribution of ground beetles as model organisms, specifically whether the ground beetle distribution increases from the outer to the inner parts of the orogen, against latitudinal effects. We also tested whether July temperature and solar radiation are predictors of the beetle's elevational distribution ranges. Finally, we discussed the general importance of these effects for the distributional and evolutionary history of the biota of High Asia. We modelled spatially explicit estimates of variables characterizing temperature and solar radiation and correlated the variables with the respective lower elevational range of 118 species of ground beetles from 76 high-alpine locations. Both July temperature and solar radiation significantly positively correlated with the elevational ranges of high-alpine beetles. Against the latitudinal trend, the median elevation of the respective species distributions increased by 800 m from the Himalayan south face north to the Transhimalaya. Our results indicate that an increase in seasonal temperature due to mass elevation and lee effects substantially impact the regional distribution patterns of alpine ground beetles of the Himalaya-Tibet orogen and are likely to affect also other soil biota there and in mountain ranges worldwide. Since these effects must have changed during orogenesis, their potential impact must be considered when biogeographic scenarios based on geological models are derived. As this has not been the practice, we believe that large biases likely exist in many paleoecological and evolutionary studies dealing with the biota from the Himalaya-Tibet orogen and mountain ranges worldwide.

Application of the Time-Dependent Mild-Slope Equations for the Simulation of Wake Effects in the Lee of a Farm of Wave Dragon Wave Energy Converters

DEFF Research Database (Denmark)

Beels, Charlotte; Troch, Peter; Visch, Kenneth De

2010-01-01

the wake effect is decreasing with increasing directional spreading. The wake in the lee of a farm of five Wave Dragon WECs, installed in a staggered grid (3 WECs in the first row and 2 WECs in the second row), is calculated for three in-between distances of respectively D, 2D and 3D, with D the distance...

Explaining the Rise in Danish Vocational Education System Dropouts: The Effect of a Youth Unemployment Program

DEFF Research Database (Denmark)

Munk, Martin D.; Park, Do-Yeun

This project focuses on the impact of Denmark’s Youth Unemployment Program(YUP) enacted in late 1990s on the rise in VET dropout rates. The Youth Unemployment Program targeted unemployed, low-educated youth to strengthen the employment possibilities and to motivate for them to undertake an educat......This project focuses on the impact of Denmark’s Youth Unemployment Program(YUP) enacted in late 1990s on the rise in VET dropout rates. The Youth Unemployment Program targeted unemployed, low-educated youth to strengthen the employment possibilities and to motivate for them to undertake...... an education. If the Youth Unemployment Program incentivized less capable/ambitious students to enter vocational education, it would increase the dropout rates via selection. This project investigates whether the program had an effect on the population characteristics of incoming VET students and the resulting...

[Therapeutic applications and promises of cellular and tissue engineering. What strategic choice for the Etablissement Français du Sang?].

Science.gov (United States)

Hervé, Patrick

2007-05-01

A new medical field, known as regeneration medicine, is developing and attracting more and more researchers and practitioners. Whereas hematopoietic cell-based therapies have already proven their efficacy in numerous--malignant or not--diseases, non-hematopoietic cell-based therapies have not. They can be useful to dozens, if not hundreds, of patients with various disorders, such as cardiopathy, diabetes, some types of cancer, osteoarticular and neurodegenerative disorders. In these fields, numerous clinical applications are possible for mesenchymal stem cells. Cell and tissue (corneas, bone, skin) therapy products require the definition of pharmaceutical standards with new European requirements in terms of quality and safety. The legitimacy of the Etablissement Français du Sang (EFS) in cell and tissue engineering activities is established, it is recognized by most specialists and by regulatory authorities and has been asserted by the orientations of its "contrat d'objectifs et de moyens". An independent committee has been set up by the EFS President to define an EFS-specific strategy. This committee made up of qualified specialists was required to draw up a rational organization plan for these activities, in order for EFS to be in a position to produce cells and tissues according to pharmaceutical standards. The committee proposals are based on economic data and an inventory of existing cell and tissue engineering activities. Public/private partnerships are required and efforts must focus towards the industrial valorization of EFS expertise in R&D activities and staff know-how. Implementing such a new organization requires national management and the cooperation of institutional actors (university hospitals, cancer treatment centers, universities). For the success of this approach, EFS personnel must be convinced of its legitimacy and new skills must be encouraged. With its numerous assets, EFS can be ambitious and assert itself as a major actor in cell and

Okhee Lee, Cory A. Buxton, James A. Banks (ed.), Diversity and equity in science education: research, policy, and practice

Science.gov (United States)

Bannier, Betsy J.

2015-06-01

Highly relevant for academic study among K-12 educators and the higher education faculty who train pre-service teachers, Diversity and equity in science education highlights three interrelated issues impacting science education in the United States. First, complicated dynamics related to the large and increasing population of English language learning (ELL) students are discussed. Second, the realities of standardized test scores are comparatively explored, both within and beyond the United States. Third, the politics of accountability in education are vigorously discussed. Okhee Lee and Cory A. Buxton weave through the contexts of politics, education, science, and culture to expand existing discourse about how to best educate our nation's children.

Différent Transfusional Regulatory Systems in the World

OpenAIRE

SLBHENGE, Zivanai

2013-01-01

L'objectif de ce projet est de comparer et contraster les différents systèmes réglementaires de transfusion sanguine dans le monde. Avec une demande toujours croissante sur des approvisionnements en sang dans le monde entier, il y - a un immense besoin d'assurer des produits sûrs et suffisants d'apport de sang. Cependant le cadre juridique pour un système de sang exprime la politique nationale de sang et décrit des mécanismes régissant la collection, le traitement et la transfusio...

Impact of the Garrett Lee Smith youth suicide prevention program on suicide mortality.

Science.gov (United States)

Walrath, Christine; Garraza, Lucas Godoy; Reid, Hailey; Goldston, David B; McKeon, Richard

2015-05-01

We examined whether a reduction in youth suicide mortality occurred between 2007 and 2010 that could reasonably be attributed to Garrett Lee Smith (GLS) program efforts. We compared youth mortality rates across time between counties that implemented GLS-funded gatekeeper training sessions (the most frequently implemented suicide prevention strategy among grantees) and a set of matched counties in which no GLS-funded training occurred. A rich set of background characteristics, including preintervention mortality rates, was accounted for with a combination of propensity score-based techniques. We also analyzed closely related outcomes that we did not expect to be affected by GLS as control outcomes. Counties implementing GLS training had significantly lower suicide rates among the population aged 10 to 24 years the year after GLS training than similar counties that did not implement GLS training (1.33 fewer deaths per 100 000; P = .02). Simultaneously, we found no significant difference in terms of adult suicide mortality rates or nonsuicide youth mortality the year after the implementation. These results support the existence of an important reduction in youth suicide rates resulting from the implementation of GLS suicide prevention programming.

Comparison of methods for calculating thermodynamic properties of binary mixtures in the sub and super critical state: Lee-Kesler and cubic equations of state for binary mixtures containing either CO2 or H2S

International Nuclear Information System (INIS)

Yang, Jyisy; Griffiths, Peter R.; Goodwin, Anthony R.H.

2003-01-01

The (ρ,T,p) and (vapor + liquid) equilibria for fluid mixtures containing either CO 2 or H 2 S have been determined from 13 equations of state. The estimated values have been compared with published experimental results. CO 2 and H 2 S were used to represent non-polar and polar fluids, respectively. The equations of state investigated were as follows: (a) the Lee-Kesler equation; (b) two equations that included new reference fluids for the Lee-Kesler method; (c) three so-called extended equations of state; and (d) seven cubic equations of state. After adjustment of the binary interaction parameters the predicted values differed from the experimental data by about 0.8% for CO 2 mixtures while for H 2 S mixtures the uncertainty was about ±2.8%. Somewhat larger errors, although still lower than ±5%, were obtained for co-existing phase densities; the Lee-Kesler method provided results of the highest accuracy. The cubic equations proposed by Schmidt and Wenzel and Valderrama provide the most reliable predictions of both single and co-existing phase densities. Comparison of the predicted (vapor + liquid) equilibrium with experiment shows that each of the seven cubic equations provides results of similar accuracy and all within ±6%

The viscous lee wave problem and its implications for ocean modelling

Science.gov (United States)

Shakespeare, Callum J.; Hogg, Andrew McC.

2017-05-01

Ocean circulation models employ 'turbulent' viscosity and diffusivity to represent unresolved sub-gridscale processes such as breaking internal waves. Computational power has now advanced sufficiently to permit regional ocean circulation models to be run at sufficiently high (100 m-1 km) horizontal resolution to resolve a significant part of the internal wave spectrum. Here we develop theory for boundary generated internal waves in such models, and in particular, where the waves dissipate their energy. We focus specifically on the steady lee wave problem where stationary waves are generated by a large-scale flow acting across ocean bottom topography. We generalise the energy flux expressions of [Bell, T., 1975. Topographically generated internal waves in the open ocean. J. Geophys. Res. 80, 320-327] to include the effect of arbitrary viscosity and diffusivity. Applying these results for realistic parameter choices we show that in the present generation of models with O(1) m2s-1 horizontal viscosity/diffusivity boundary-generated waves will inevitably dissipate the majority of their energy within a few hundred metres of the boundary. This dissipation is a direct consequence of the artificially high viscosity/diffusivity, which is not always physically justified in numerical models. Hence, caution is necessary in comparing model results to ocean observations. Our theory further predicts that O(10-2) m2s-1 horizontal and O(10-4) m2s-1 vertical viscosity/diffusivity is required to achieve a qualitatively inviscid representation of internal wave dynamics in ocean models.

Identity as Fleeting Fashion? Revealing the Background of Popularity Through Bosniaherzegovina’s Adoption of Bruce Lee

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Alenka Bartulović

2007-12-01

Full Text Available This paper reflects on the background to popular research on identification processes in modern ethnology and cultural or social anthropology. By discussing themes closely connected to identity (national and popular culture, and the construction of Others, the author reveals that identity is not merely a redundant trend that researchers recklessly pursue, but that it reflects the need to reveal existing uncertainties and is an attempt to revise errors made to date, as well as lapses of the discipline we work in. The author primarily focuses on national identity and its situational transformations and intertwining with other existing identities. Bosnia-Herzegovina is placed at the center of interest. This theoretically oriented text concludes by analyzing the idea of erecting a monument to Bruce Lee in Mostar, which reveals the full complexity of identity processes around a world marked by intense and unique global and transnational currents.

The Taiwanese Perspective in Investigating Korean Confucianism: Lee Ming-huei's Interpretation of Han Wonjin (1682–1750

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Martina GREIF

2014-12-01

Full Text Available Numerous representatives of the contemporary Confucian revival from Taiwan are increasingly demonstrating the fact that the development of Confucian philosophy has to be viewed in a broader cultural context, especially in the context of different East Asian regions. While the development of the Japanese Confucian studies has been elaborated to a great extent during the last decades, studies in Korean Confucianism are still rare. Hence, the present article aims to offer a report on a pioneer contribution in this regard. It introduces Lee Ming-huei’s investigation into the work of one of the most influential Korean Confucians of the Joseon period; on the basis of Huang Chun-chieh’s methodology which exposes the contextualization paradigm, the article explains the main hypotheses and offers a theoretical reflection of the main issues discussed in this research work.

Systematic identification of yeast proteins extracted into model wine during aging on the yeast lees.

Science.gov (United States)

Rowe, Jeffrey D; Harbertson, James F; Osborne, James P; Freitag, Michael; Lim, Juyun; Bakalinsky, Alan T

2010-02-24

Total protein and protein-associated mannan concentrations were measured, and individual proteins were identified during extraction into model wines over 9 months of aging on the yeast lees following completion of fermentations by seven wine strains of Saccharomyces cerevisiae. In aged wines, protein-associated mannan increased about 6-fold (+/-66%), while total protein only increased 2-fold (+/-20%), which resulted in a significantly greater protein-associated mannan/total protein ratio for three strains. A total of 219 proteins were identified among all wine samples taken over the entire time course. Of the 17 "long-lived" proteins detected in all 9 month samples, 13 were cell wall mannoproteins, and four were glycolytic enzymes. Most cytosolic proteins were not detected after 6 months. Native mannosylated yeast invertase was assayed for binding to wine tannin and was found to have a 10-fold lower affinity than nonglycosylated bovine serum albumin. Enrichment of mannoproteins in the aged model wines implies greater solution stability than other yeast proteins and the possibility that their contributions to wine quality may persist long after bottling.

Comparisons of predictive values of sarcopenia with different muscle mass indices in Korean rural older adults: a longitudinal analysis of the Aging Study of PyeongChang Rural Area

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Jang IY

2018-01-01

Full Text Available Il-Young Jang,1,2,* Hee-Won Jung,3,4,* Chang Ki Lee,5 Sang Soo Yu,2 Young Soo Lee,1 Eunju Lee1 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 2PyeongChang Health Center & County Hospital, Gangwon-Do, 3Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST, Daejeon, 4Geriatric Center, Seoul National University Bundang Hospital, Gyeonggi-Do, 5Goldman Urology Clinic, Seoul, Republic of Korea *These authors contributed equally to this work Purpose: It is important to define lean muscle mass when diagnosing sarcopenia, but there is still controversy on the clinical implication of sarcopenia derived by height, weight, and body mass index (BMI adjusted muscle mass indices. We aimed to evaluate the longitudinal clinical relevance of 3 sarcopenia definitions in the Korean population. Patients and methods: We conducted comprehensive geriatric assessments for 1,379 community-dwelling older participants in the Aging Study of PyeongChang Rural Area (ASPRA cohort and followed them up prospectively for death, institutionalization, and disability every 3 months. Sarcopenia was defined using the Asian Working Group consensus algorithm, combining grip strength, gait speed, and muscle mass.Results: Among 1,343 participants (mean age: 76 years, 741 women analyzed, there were 29 deaths and 89 institutionalizations during 22.0 ± 8.3 months follow-up (mean ± SD. All three muscle indices correlated to age and sex. All sarcopenia criteria with muscle mass indices of height, weight, and body mass index (BMI adjustment significantly predicted death or institutionalization. However, when adjusted for age and sex, only the sarcopenia criteria with muscle mass index of height adjustment were significantly associated with major adverse health outcomes.Conclusion: Adjusting age and gender, the sarcopenia definition from the quintile-based muscle index of height

Mesophilic and thermophilic anaerobic co-digestion of winery wastewater sludge and wine lees: An integrated approach for sustainable wine production.

Science.gov (United States)

Da Ros, C; Cavinato, C; Pavan, P; Bolzonella, D

2017-12-01

In this work, winery wastes generated by a cellar producing approximately 300,000 hL of wine per year was monitored for a period of one year. On average, 196 L of wastewater, 0.1 kg of waste activated sludge (dry matter) and 1.6 kg of wine lees were produced per hectoliter of wine produced. Different winery wastes, deriving from different production steps, namely waste activated sludge from wastewater treatment and wine lees, were co-treated using an anaerobic digestion process. Testing was conducted on a pilot scale for both mesophilic and thermophilic conditions. The process was stable for a long period at 37 °C, with an average biogas production of 0.386 m 3 /kg COD fed . On the other hand, for thermophilic conditions, volatile fatty acids accumulated in the reactor and the process failed after one hydraulic retention time (23 days). In order to fix the biological process, trace elements (iron, cobalt and nickel) were added to the feed of the thermophilic reactor. Metals augmentation improved process stability and yields at 55 °C. The pH ranged between 7.8 and 8.0, and specific gas production was 0.450 m 3 /kg COD fed , which corresponded to dry matter and COD removals of 34% and 88%, respectively. Although the observed performances in terms of biogas production were good, the thermophilic process exhibited some limitations related to both the necessity of metals addition and the worse dewaterability properties. In fact, while the mesophilic digestates reached a good dewatering quality via the addition of 6.5 g of polymer per kg of dry matter, the required dosage for the thermophilic sludge was greater than 10 g/kg of dry matter. Copyright © 2016 Elsevier Ltd. All rights reserved.

Lauren Berlant and Lee Edelman, Sex, Or The Unbearable (Durham: Duke University Press, 2014, pp. 168, ISBN: 9780822355946, £13.99, paperback.

Directory of Open Access Journals (Sweden)

Hannah Proctor

2014-01-01

Full Text Available 'So few colleges and universities bother to teach human sexuality...so much stigma adheres even to scholarly investigation of sex,' Gayle Rubin lamented in her 1984 essay 'Thinking Sex'. But it was an academic conference on Rubin's work - 'Rethinking Sex', a lavish threeday event, held at the University of Pennsylvania in 2009 - that provided the initial impetus for Lauren Berlant and Lee Edelman to enter into a dialogue on sexuality. The result is Sex, or the Unbearable, published by Duke University Press, the first in a series on queer theory edited by the authors.

Reattachment Zone Characterisation Under Offshore Winds With Flow Separation On The Lee Side Of Coastal Dunes

Science.gov (United States)

Delgado-Fernandez, I.; Jackson, D.; Cooper, J. A.; Baas, A. C.; Lynch, K.; Beyers, M.

2010-12-01

Airflow separation, lee-side eddies and secondary flows play an essential role on the formation and maintenance of sand dunes. Downstream from dune crests the flow surface layer detaches from the ground and generates an area characterised by turbulent eddies in the dune lee slope (the wake). At some distance downstream from the dune crest, flow separates into a reversed component directed toward the dune toe and an offshore “re-attached” component. This reattachment zone (RZ) has been documented in fluvial and desert environments, wind tunnel experiments and numerical simulations, but not yet characterised in coastal dunes. This study examines the extent and temporal evolution of the RZ and its implications for beach-dune interaction at Magilligan, Northern Ireland. Wind parameters were measured over a profile extending from an 11 m height dune crest towards the beach, covering a total distance of 65 m cross-shore. Data was collected using an array of nine ultrasonic anemometers (UAs) deployed in April-May 2010, as part of a larger experiment to capture airflow data under a range of incident wind velocities and offshore directions. UAs were located along the profile (5 m tower spacing) over the beach, which allowed a detailed examination of the RZ with empirical data. Numerical modelling using Computational Fluid Dynamics (CFD) software was also conducted with input data from anemometer field measurements, running over a surface mesh generated from LiDAR and DGPS surveys. Results demonstrate that there is a wind threshold of approximately 5-6 ms-1 under which no flow separation exists with offshore winds. As wind speed increases over the threshold, a flow reversal area is quickly formed, with the maximum extent of the RZ at approximately 3.5 dune heights (h). The maximum extent of the RZ increases up to 4.5h with stronger wind speeds of 8-10 ms-1 and remains relatively constant as wind speed further increases. This suggests that the spatial extent of the RZ is

Sing English: Om sangens potensial i engelskopplæringen

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Ragnhild Elisabeth Lund

2012-03-01

Full Text Available Sang er en åpenbar kilde til læring av fremmedspråk. Læreplaner for engelskfaget opp gjennom tidene har påpekt dette, og læreverkene i engelsk inneholder mange sanger. Men nøyaktig hva er det sang kan bidra med? Hva slags sanger er tatt med i bøkene, og hvilke målsettinger ser ut til å være knyttet til dem? Artikkelen besvarer disse spørsmålene ved å vise til læreplaner og utvalgte lærebøker fra perioden 1885 – 2008 og hvordan de legger opp til at sang skal brukes som en del av opplæringen i engelsk. Undersøkelsen er begrenset til ungdomstrinnet. Innledningsvis refererer artikkelen til ulike begrunnelser for bruk av sang i fremmedspråkopplæringen. Når sang nevnes i læreplanene eller innlemmes i lærebøkene, reflekteres enkelte av disse begrunnelsene. Samtidig er det påfallende hvor ofte planer og bøker ikke begrunner bruken av sang eller setter sangene inn i en didaktisk sammenheng. Artikkelen konkluderer derfor med at sanger ser ut til å representere et stort, men delvis uutnyttet potensial i engelskopplæringen på ungdomstrinnet.

Protective effect of topical application of α-tocopherol and/or N-acetyl cysteine on argemone oil/alkaloid-induced skin tumorigenesis in mice.

Science.gov (United States)

Pal, Anu; Alam, Shamshad; Singhal, Jaya; Kumar, Rahul; Ansari, Kausar M; Das, Mukul

2013-01-01

Since bioantioxidants in plasma of Epidemic Dropsy patients [a condition caused by consumption of adulterated mustard oil with argemone oil (AO)] were found to be significantly decreased, the beneficial effect of N-acetyl cysteine (NAC) and α-tocopherol (TOCO) against AO- or sanguinarine (SANG)-induced tumorigenicity was undertaken in mice. Topical application of TOCO and NAC either alone or in combination showed significant protection against AO/TPA- and SANG/TPA-induced skin tumorigenicity. Histopathological findings suggest that papillomatous growth in AO/TPA- and SANG/TPA-treated animals were substantially protected following topical application of TOCO or NAC. Further, treatment of TOCO and NAC either alone or in combination to AO/TPA- or SANG/TPA-induced mice significantly decreased lipid peroxidation, along with significant revival in glutathione (GSH) content and activities of tyrosinase, histidase, catalase, SOD, GSH peroxidase, and GSH reductase in skin. In vitro studies showed that TOCO and/or NAC significantly decreased the AO and SANG induced cell proliferation and activation of ERK, p38, JNK MAPKs and NF-κB signaling in HaCaT cells. In summary, TOCO and NAC may be useful in preventing the tumorigenic response of AO and SANG probably by acting as scavenger of free radicals and inhibiting MAPKs and NF-κB signaling.

Sang i Demensplejen

DEFF Research Database (Denmark)

Ridder, Hanne Mette Ochsner

2004-01-01

For mange svært demensramte er det umuligt at deltage i en aktivitet med andre personer. De har svært ved at forstå, hvad der foregår omkring dem, og bliver urolige og "forstyrrende". Eller de falder i søvn. Artiklen giver et bud på, hvordan den gruppe af demensramte, som ofte beskrives som uroli...

Topography and vegetation as predictors of snow water equivalent across the alpine treeline ecotone at Lee Ridge, Glacier National Park, Montana, U.S.A.

Science.gov (United States)

Geddes, C.A.; Brown, D.G.; Fagre, D.B.

2005-01-01

We derived and implemented two spatial models of May snow water equivalent (SWE) at Lee Ridge in Glacier National Park, Montana. We used the models to test the hypothesis that vegetation structure is a control on snow redistribution at the alpine treeline ecotone (ATE). The statistical models were derived using stepwise and "best" subsets regression techniques. The first model was derived from field measurements of SWE, topography, and vegetation taken at 27 sample points. The second model was derived using GIS-based measures of topography and vegetation. Both the field- (R² = 0.93) and GIS-based models (R² = 0.69) of May SWE included the following variables: site type (based on vegetation), elevation, maximum slope, and general slope aspect. Site type was identified as the most important predictor of SWE in both models, accounting for 74.0% and 29.5% of the variation, respectively. The GIS-based model was applied to create a predictive map of SWE across Lee Ridge, predicting little snow accumulation on the top of the ridge where vegetation is scarce. The GIS model failed in large depressions, including ephemeral stream channels. The models supported the hypothesis that upright vegetation has a positive effect on accumulation of SWE above and beyond the effects of topography. Vegetation, therefore, creates a positive feedback in which it modifies its, environment and could affect the ability of additional vegetation to become established.

Concentrações sangüíneas de metais pesados e praguicidas organoclorados em crianças de 1 a 10 anos Heavy metal and organochlorine pesticide blood levels in children aged between 1 and 10

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Eladio Santos Filho

1993-02-01

Full Text Available Foi realizado estudo em 6 bairros do Município de Cubatão, SP, Brasil, situados às margens dos principais rios do município, com uma amostragem de 251 crianças de 1 a 10 anos de idade. Foram verificadas as concentrações sangüíneas de praguicidas organoclorados em 242 crianças, sendo que 73 crianças (30% apresentaram concentrações de p-p'DDE (média = 0,85 ± 2,13 µg/l., e em 47 crianças (19% foi encontrado HCH total (média = 0,28 ± 0,79 µg/l.. Verificou-se também a concentração sangüínea de chumbo e mercúrio, sendo que se obteve a plumbemia média de 17,8 ± 5,8 µg/dl. e concentração média de mercúrio de 9,1 ± 6,4 µg/l. Crianças consumidoras de organismos aquáticos de origem exclusiva dos rios de Cubatão apresentaram teores médios de mercúrio (média = 14,7 ±7,1 µg/l. significativamente maiores (p A study of a sample of 251 children aged between 1 and 10 was carried out in 6 districts of Cubatão county, S. Paulo State, Brazil. This study showed the presence of organochlorine pesticides in the blood serum of 242 children, p-p' DDE was detected in 73 of the samples (30% and HCH in 47 them (19%. The mean value of p-p' DDE was 0.85 ± 2.13 µg/l. and that of HCH was 0.28 ± 0.79 µg/l. Lead and mercury were also detected in the blood serum. The mean value for lead was 17.8 ± 5.8 µg/l. and for mercury was 9.1 ± 0.79 µg/l. The levels found in consumers of aquatic organisms taken from the rivers of Cubatão showed a mean mercury level (mean = 14.7 ± 7.1 µg/l. higher than (p < 0.04 that of those who did not consume any aquatic organisms at all (mean = 10.0 ± 6.5 µg/l..

Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers

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Jang K

2017-03-01

Full Text Available Kyungho Jang,1,2,* Min-Kyoung Kim,3,4,* Jaeseong Oh,1 SeungHwan Lee,1 Joo-Youn Cho,1 Kyung-Sang Yu,1 Tai Kiu Choi,3 Sang-Hyuk Lee,3,4 Kyoung Soo Lim4 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 2Center for Clinical Pharmacology and Biomedical Research Institute, Chonbuk National University Medical School, Jeonju, 3Department of Psychiatry, 4Department of Clinical Pharmacology and Therapeutics, CHA University School of Medicine and CHA Bundang Medical Center, Seongnam, Republic of Korea *These authors contributed equally to this work Purpose: Oseltamivir is widely used in the treatment and prophylaxis of influenza A and B viral infections. It is ingested as an oral prodrug that is rapidly metabolized by carboxylesterase 1 (CES1 to its active form, oseltamivir carboxylate. Dexamethasone is also used in the treatment of acute respiratory distress syndrome, a severe complication of influenza; however, its influence on the pharmacokinetics (PK of oseltamivir is controversial. The aim of this study was to investigate the effects of coadministering oseltamivir and dexamethasone on the PK of oseltamivir in healthy volunteers. Methods: An open-label, two-period, one-sequence, multiple-dose study was conducted in 19 healthy male volunteers. Oseltamivir (75 mg was orally administered on Day 1 and Day 8, and dexamethasone (1.5 mg was administered once daily from Day 3 to Day 8. Serial blood and urine samples were collected for PK analysis of oseltamivir and oseltamivir carboxylate on Day 1 and Day 8. Oseltamivir and oseltamivir carboxylate concentrations in plasma and urine were determined using liquid chromatography–tandem mass spectrometry. Results: Area under the plasma concentration–time curve (AUC of oseltamivir and oseltamivir carboxylate decreased after dexamethasone treatment for 6 days. The geometric mean ratio (90% confidence interval of the metabolic ratio

Development of an immunotherapeutic adenovirus targeting hormone-independent prostate cancer

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Kim JS

2013-11-01

Full Text Available Jae Sik Kim,1 Sang Don Lee,2 Sang Jin Lee,3 Moon Kee Chung21Department of Urology, The Catholic University of Korea Incheon St Mary's Hospital, Incheon, 2Pusan National University Yangsan Hospital and Research Institute for Convergence of Biomedical Science and Technology, Yangsan, 3Genitourinary Cancer Branch, National Cancer Center, Goyang, KoreaBackground: To develop a targeting therapy for hormone-independent prostate cancer, we constructed and characterized conditionally replicating oncolytic adenovirus (Ad equipped with mRFP(monomeric red fluorescence protein/ttk (modified herpes simplex virus thymidine kinase This construct was then further modified to express both mRFP/ttk and a soluble form of cytokine FLT3L (fms-related tyrosine kinase 3 ligand simultaneously.Methods: To construct the recombinant oncolytic adenovirus, E1a and E4 genes, which are necessary for adenovirus replication, were controlled by the prostate-specific enhancer sequence (PSES targeting prostate cancer cells expressing prostate-specific antigen (PSA and prostate-specific membrane antigen (PSMA. Simultaneously, it expressed the mRFP/ttk fusion protein in order to be able to elicit the cytotoxic effect.Results: The Ad5/35PSES.mRFP/ttk chimeric recombinant adenovirus was generated successfully. When replication of Ad5/35PSES.mRFP/ttk was evaluated in prostate cancer cell lines under fluorescence microscopy, red fluorescence intensity increased more in LNCaP cells, suggesting that the mRFP/ttk fusion protein was folded functionally. In addition, the replication assay including wild-type adenovirus as a positive control showed that PSES-positive cells (LNCaP and CWR22rv permitted virus replication but not PSES-negative cells (DU145 and PC3. Next, we evaluated the killing activity of this recombinant adenovirus. The Ad5/35PSES.mRFP/ttk killed LNCaP and CWR22rv more effectively. Unlike PSES-positive cells, DU145 and PC3 were resistant to killing by this recombinant

Neutrino mixing: from the broken μ-τ symmetry to the broken Friedberg–Lee symmetry

International Nuclear Information System (INIS)

Xing, Zhizhong

2007-01-01

I argue that the observed flavor structures of leptons and quarks might imply the existence of certain flavor symmetries. The latter should be a good starting point to build realistic models towards deeper understanding of the fermion mass spectra and flavor mixing patterns. The μ-τ permutation symmetry serves for such an example to interpret the almost maximal atmospheric neutrino mixing angle (θ 23 ~ 45°) and the strongly suppressed CHOOZ neutrino mixing angle (θ 13 < 10°). In this talk I like to highlight a new kind of flavor symmetry, the Friedberg–Lee symmetry, for the effective Majorana neutrino mass operator. Luo and I have shown that this symmetry can be broken in an oblique way, such that the lightest neutrino remains massless but an experimentally-favored neutrino mixing pattern is achievable. We get a novel prediction for θ 13 in the CP-conserving case: sinθ 13 = tanθ 12 |(1 - tanθ 23 )/(1 + tanθ 23 )|. Our scenario can simply be generalized to accommodate CP violation and be combined with the seesaw mechanism. Finally I stress the importance of probing possible effects of μ-τ symmetry breaking either in terrestrial neutrino oscillation experiments or with ultrahigh-energy cosmic neutrino telescopes. (author)

A cross-sectional study of correlation of body image anxiety with social phobia and their association with depression in the adolescents from a rural area of Sangli district in India

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Vivek Baliram Waghachavare

2014-01-01

Full Text Available Background: Prevailing socio-cultural influences lead females to desire a thin body and males a muscular body, especially in adolescents. This results in body image anxiety which may lead to social phobia. Together they can develop depression. The aim was to study the correlation of body image anxiety with social phobia and their association with depression, among adolescents. Methods: This was a cross-sectional study conducted in randomly selected colleges from a rural area of Sangli district Maharashtra, India. Stratified random sampling technique used with sample size 805. Pretested self-administered questionnaire used. Percentage, Chi-square test, binary logistic regression model was used to estimate odds ratio (OR and its 95% confidence intervals. Results: Of 997 study subjects body image anxiety, social phobia and depression were observed in 232 (23.3%, 193 (19.4% and 326 (32.7% participants, respectively. Binary logistic regression showed that body image anxiety (OR = 1.849 [1.22, 2.804]; P = 0.004 and social phobia (OR = 4.575 [2.952-7.09]; P < 0.001 were significant predictors for depression. Conclusions: Body image anxiety and social phobia are linked with the development of depression. This impresses the need for timely counseling and education among adolescents.

Demographic and fertility characteristics of 4 squatter settlements.

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Yusof, K; Zulkifli, S N

1985-01-01

The demographic and fertility profiles of 4 squatter areas, 2 with Sang Kancil, a community development project designed specifically for squatter settlements in Kuala Lumpur, are described. Data were taken from a census conducted in 1982. Figure 1 maps out the location of the study areas in the Federal Territory. The squatter household (5.4 members) varied little from the average Malaysian household. The average age of the male head of household was 40 years, i.e., not within the high fertility group; the mean duration of stay was 10 years. Household income/month averaged M$760, falling between estimates for urban and rural mean. Comparing the data on the 2 squatter areas, the non-Sang Kancil head of household was, on average, slightly older and had stayed about 2 years longer than his Sang Kancil counterpart. These differences were statistically significant. Both areas were comparable with regard to household income and size. Ethnically, the Sang Kancil areas were predominantly Malay, comprising 86% of total households. The control areas had a more mixed ethnic structure. From 1978-81, annual increases in total population had been fairly uniform, at around 2%, in non-Sang Kancil Areas. Yet, the Sang Kancil population experienced a growth spurt in 1980, which subsequently declined and appeared to level off. 1982 figures were disregarded in this analysis as they were based on a 1/2 year enumeration only. The age distribution pattern of all squatter areas combined was fairly similar to the national distribution pyramid but for a higher proportion of people in the 15-44 age group than national figures. The proportion of dependents, 0-14 years, was comparable despite having more people in this fertile age group. The proportion of infants (0-11 months) in the control population was constant, but there was a decline down to control values by the end of the surveyed period in the Sang Kancil group. In the toddler group, decreases were evident for both populations

IDENTIFICATION OF ODOR SUBSTANCES IN YAMABUSHITAKE MUSHROOM (Hericium erinaceum) CULTURE MEDIA CONTAINING 'SHOCHU' LEES AND STARCH WASTES, AND BASIC STUDIES ON THEIR DISAPPEARANCE

Science.gov (United States)

Yamauchi, Masahito; Matsumoto, Hirotaka; Yamada, Masayoshi; Yagi, Fumio; Murayama, Ryou; Yamaguchi, Yoshinori; Yamaguchi, Takashi

In this study, odor substances from mushroom culture media containing 'shochu' lees and starch wastes were identified and determined. It was apparent that in the media, acetoin, butyric acid and diacetyl were found as main odor substances, and mixed with some other ordor substances to produce unpleasant odor. The main substances disappeared with growth of mycelia. It was not likely that these ordor substances were degraded by extracellular enzymes but suggested that they were degraded by mycelia. Further it was found with the growth of mycelia that odor quality changed from rancid ordor (unpleasant ordor) to mushroom smell (pleasant odor) and the odor index was decreasing.

Unexpected Climatological Behavior of MLT Gravity Wave Momentum Flux in the Lee of the Southern Andes Hot Spot

Science.gov (United States)

DeWit, R. J.; Janches, D.; Fritts, D. C.; Stockwell, R. G.; Coy, L.

2017-01-01

The Southern Argentina Agile MEteor Radar (SAAMER), located at Tierra del Fuego (53.7degS, 67.7degW), has been providing near-continuous high-resolution measurements of winds and high-frequency gravity wave (GW) momentum fluxes of the mesopause region since May 2008. As SAAMER is located in the lee of the largest seasonal GW hot spot on Earth, this is a key location to study GWs and their interaction with large-scale motions. GW momentum flux climatologies are shown for the first time for this location and discussed in light of these unique dynamics. Particularly, the large eastward GW momentum fluxes during local winter are surprising, as these observations cannot be explained by the direct upward propagation of expected large-amplitude mountain waves (MWs) through the eastward stratospheric jet. Instead, these results are interpreted as secondary GWs propagating away from stratospheric sources over the Andes accompanying MW breaking over the Southern Andes.

Detergents enhance EspB secretion from Escherichia coli strains harboring the locus for the enterocyte effacement (LEE) gene.

Science.gov (United States)

Nakasone, Noboru; Toma, Claudia; Higa, Naomi; Koizumi, Yukiko; Ogura, Yasunori; Suzuki, Toshihiko

2011-02-01

The effects of detergents (cholic acid, deoxycholic acid, Triton X-100, and Nonidet P-40) on the secretion of EspB from the locus for enterocyte effacement (LEE) gene-positive Escherichia coli strains were examined. Clinical isolates of eight EPEC strains and seven STEC strains were used to detect EspB after they had been cultivated in Luria-Bertani (LB) broth containing one of the detergents. When the bacteria were cultured in LB broth supplemented with one of the detergents, the amount of EspB produced was increased by 2-32-fold depending on the detergent and the strain used. EspB was detected in all strains when they were cultured in LB broth containing all of the detergents. The results obtained in this study can be applied to immunological diagnostic methods for detecting EspB and also to the production of EspB for research purposes. © 2010 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

Rural Alaska Mentoring Project (RAMP)

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Cash, Terry

2011-01-01

For over two years the National Dropout Prevention Center (NDPC) at Clemson University has been supporting the Lower Kuskokwim School District (LKSD) in NW Alaska with their efforts to reduce high school dropout in 23 remote Yup'ik Eskimo villages. The Rural Alaska Mentoring Project (RAMP) provides school-based E-mentoring services to 164…

Influence of Quaternary Benzophenantridine and Protopine Alkaloids on Growth Performance, Dietary Energy, Carcass Traits, Visceral Mass, and Rumen Health in Finishing Ewes under Conditions of Severe Temperature-humidity Index

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A. Estrada-Angulo

2016-05-01

Full Text Available Twenty Pelibuey×Katahdin ewes (35±2.3 kg were used to determine the effects of the consumption of standardized plant extract containing a mixture of quaternary benzophenanthridine alkaloids and protopine alkaloids (QBA+PA on growth performance, dietary energetics, visceral mass, and ruminal epithelial health in heat-stressed ewes fed with a high-energy corn-based diet. The basal diet (13.9% crude protein and 2.09 Mcal of net energy [NE] of maintenance/kg of dry matter contained 49.7% starch and 15.3% neutral detergent fiber. Source of QBA+PA was Sangrovit RS (SANG which contains 3 g of quaternary benzophenathridine and protopine alkaloids per kg of product. Treatments consisted of a daily consumption of 0 or 0.5 g SANG/ewe. Ewes were grouped by weight and assigned to 10 pens (5 pens/treatment, with two ewes per pen. The experimental period lasted 70 days. The mean temperature humidity index during the course of this experiment was 81.7±1.0 (severe heat stress. There were no treatment effects on water intake. Dry matter intake was not affected (p = 0.70 by treatments, but the group fed SANG had a numerically (11.2% higher gain in comparison to the control group, SANG improved gain efficiency (8.3%, p = 0.04, dietary NE (5.2%, p<0.01 and the observed-to-expected NE (5.9%, p<0.01. Supplemental SANG did not affect (p≥0.12 carcass characteristics, chemical composition of shoulder, and organ weights (g/kg empty body weight of stomach complex, intestines, and heart/lung. Supplemental SANG decreased liver weight (10.3%, p = 0.02 and increased visceral fat (16.9%, p = 0.02. Rumen epithelium of ewes fed SANG had lower scores for cellular dropsical degeneration (2.08 vs 2.34, p = 0.02, parakeratosis (1.30 vs 1.82, p = 0.03 and neutrophil infiltration (2.08 vs 2.86, p = 0.05 than controls. It is concluded that SANG supplementation helped ameliorate the negative effects of severe heat on growth performance of feedlot ewes fed high-energy corn

Biosafety of spray dried porcine plasma for different viruses of interest for the swine industry

OpenAIRE

Pujols i Romeu, Joan

2015-01-01

El productes de plasma dessecat per esprai (SDP) tenen un alt contingut proteic i són components útils per a moltes aplicacions, principalment com a productes valuosos per la nutrició animal. El plasma s'obté a partir de sang de porcs sans aptes pel consum humà. Durant l'obtenció, s'afegeixen anticoagulants i la sang s'emmagatzema en tancs refrigerats. Un cop a la planta de processament, la sang es centrifuga, per separar el plasma de la fracció cel∙lular. El plasma es deshidrata en un procés...

Structural modeling of age specific fertility curves in Peninsular Malaysia: An approach of Lee Carter method

Science.gov (United States)

Hanafiah, Hazlenah; Jemain, Abdul Aziz

2013-11-01

In recent years, the study of fertility has been getting a lot of attention among research abroad following fear of deterioration of fertility led by the rapid economy development. Hence, this study examines the feasibility of developing fertility forecasts based on age structure. Lee Carter model (1992) is applied in this study as it is an established and widely used model in analysing demographic aspects. A singular value decomposition approach is incorporated with an ARIMA model to estimate age specific fertility rates in Peninsular Malaysia over the period 1958-2007. Residual plots is used to measure the goodness of fit of the model. Fertility index forecast using random walk drift is then utilised to predict the future age specific fertility. Results indicate that the proposed model provides a relatively good and reasonable data fitting. In addition, there is an apparent and continuous decline in age specific fertility curves in the next 10 years, particularly among mothers' in their early 20's and 40's. The study on the fertility is vital in order to maintain a balance between the population growth and the provision of facilities related resources.

Dreams of the Hmong Kingdom: The Quest for Legitimation in French Indochina, 1850- 1960, by Mai Na M. Lee. Madison, University of Wisconsin Press, 2015. 430 pages.

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Nengher N. Vang

2015-12-01

Full Text Available This article provides a book review of Mai Na M. Lee’s Dreams of the Hmong Kingdom: The Quest for Legitimation in French Indochina, 1850-1960. Dreams of the Hmong Kingdom. It highlights the contribution of the book to the historiography of the Hmong and provides a critical assessment of the dichotomous analytical framework that Lee uses to analyze the rivalry between Hmong messianic leaders and Hmong political brokers and the competition between the Ly and Lo clans for paramountcy in French Indochina

O Vigia de O Sol é Para Todos: representações do racismo e das relações raciais sulistas na obra de Harper Lee

OpenAIRE

Goulart, Henrique Rodrigues de Paula

2017-01-01

O presente trabalho dedica-se a uma leitura crítica de O Sol é Para Todos, célebre romance publicado em 1960 pela escritora norte-americana Harper Lee e adaptado para o cinema em 1962. A  proposta consiste em compreender as representações históricas produzidas pelas obras – literária e fílmica – acerca dos embates raciais atravessados pelo Sul dos Estados Unidos no contexto do Movimento pelos Direitos Civis. Por último, pretende-se comparar tais representações às de Vá, Coloque um Vigia, vers...

Diagnosis of prostate cancer via nanotechnological approach

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Kang BJ

2015-10-01

Full Text Available Benedict J Kang,1,2,* Minhong Jeun,1,2,* Gun Hyuk Jang,1,2 Sang Hoon Song,3 In Gab Jeong,3 Choung-Soo Kim,3 Peter C Searson,4 Kwan Hyi Lee1,2 1KIST Biomedical Research Institute, 2Department of Biomedical Engineering, Korea University of Science and Technology (UST, 3Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea; 4Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA *These authors contributed equally to this work Abstract: Prostate cancer is one of the leading causes of cancer-related deaths among the Caucasian adult males in Europe and the USA. Currently available diagnostic strategies for patients with prostate cancer are invasive and unpleasant and have poor accuracy. Many patients have been overly or underly treated resulting in a controversy regarding the reliability of current conventional diagnostic approaches. This review discusses the state-of-the-art research in the development of novel noninvasive prostate cancer diagnostics using nanotechnology coupled with suggested diagnostic strategies for their clinical implication.Keywords: bioassay, nanomaterial, nanodevice, PSA, non-PSA biomarker, bodily fluid

An extract of a formula used in the traditional chinese medicine (Buzhong Yi Qi Wan alters the labeling of blood constituents with technetium-99m

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Tania Santos Giani

2007-09-01

Full Text Available Buzhong Yi Qi Wan (Buzhong is a medicinal herb widely used in Traditional Chinese Medicine to treat the digestive and circulatory systems. Red blood cell and plasma proteins labeled with technetium-99m (99mTc are used in nuclear medicine. The aim of this work was to investigate the effects of an aqueous Buzhong extract on the labeling of blood constituents with 99mTc. Heparinized blood (Wistar rats was incubated in vitro with different Buzhong extract concentrations and 99mTc-labeling was performed. Plasma (P and blood cells (BC were separated and soluble (SF-P, SF-BC and insoluble (IF-P, IF-BC fractions were isolated. The radioactivity on blood constituents was determined and the percentage of incorporated radioactivity (%ATI was calculated. Buzhong extract at the highest concentrations used altered significantly (pBuzhong Yi Qi Wan (Buzhong é uma fórmula utilizada na Medicina Tradicional Chinesa para tratamento de distúrbios nos sistemas digestório e circulatório. Constituintes sangüíneos marcados com tecnécio-99m (99mTc são usados na medicina nuclear. O objetivo deste estudo foi investigar os efeitos do extrato de Buzhong na marcação de constituintes sangüíneos com 99mTc. Amostras de sangue de ratos Wistar foram incubadas com diferentes concentrações do extrato de Buzhong e a marcação de constituintes sangüíneos com 99mTc foi realizado. Plasma e células sangüíneas foram separados, frações solúveis e insolúveis do plasma e das células sangüíneas foram isoladas. A radioatividade nos constituintes sangüíneos foi contada e as porcentagens de radioatividade incorporada (%ATI, determinada. Extrato de Buzhong nas maiores concentrações utilizadas altera significativamente (p<0.05 a %ATI nos constituintes sangüíneos. Substâncias presentes no extrato de Buzhong poderiam alterar a membrana celular e/ou gerar radicais livres, que têm propriedades oxidantes, modificando a marcação dos constituintes sangüíneos com

Social networks and inference about unknown events: A case of the match between Google's AlphaGo and Sedol Lee.

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Jonghoon Bae

Full Text Available This study examines whether the way that a person makes inferences about unknown events is associated with his or her social relations, more precisely, those characterized by ego network density that reflects the structure of a person's immediate social relation. From the analysis of individual predictions over the Go match between AlphaGo and Sedol Lee in March 2016 in Seoul, Korea, this study shows that the low-density group scored higher than the high-density group in the accuracy of the prediction over a future state of a social event, i.e., the outcome of the first game. We corroborated this finding with three replication tests that asked the participants to predict the following: film awards, President Park's impeachment in Korea, and the counterfactual assessment of the US presidential election. Taken together, this study suggests that network density is negatively associated with vision advantage, i.e., the ability to discover and forecast an unknown aspect of a social event.

Demixing and nematic behaviour of oblate hard spherocylinders and hard spheres mixtures: Monte Carlo simulation and Parsons-Lee theory

Science.gov (United States)

Gámez, Francisco; Acemel, Rafael D.; Cuetos, Alejandro

2013-10-01

Parsons-Lee approach is formulated for the isotropic-nematic transition in a binary mixture of oblate hard spherocylinders and hard spheres. Results for the phase coexistence and for the equation of state in both phases for fluids with different relative size and composition ranges are presented. The predicted behaviour is in agreement with Monte Carlo simulations in a qualitative fashion. The study serves to provide a rational view of how to control key aspects of the behaviour of these binary nematogenic colloidal systems. This behaviour can be tuned with an appropriate choice of the relative size and molar fractions of the depleting particles. In general, the mixture of discotic and spherical particles is stable against demixing up to very high packing fractions. We explore in detail the narrow geometrical range where demixing is predicted to be possible in the isotropic phase. The influence of molecular crowding effects on the stability of the mixture when spherical molecules are added to a system of discotic colloids is also studied.

The Impact of Youth Unemployment Policy

DEFF Research Database (Denmark)

Filges, Trine; Larsen, Birthe

This paper examines the impact of unemployment, unemployment distribution, wages and welfare of Youth Unemployment Programmes (YUPs). This paper analyse what happens when the number of skilled workers increases relatively to the number of unskilled workers. The results depend on the productivity...... of the skilled workers when employed in the "skilled sector" relatively to the productivity of the unskilled worker....

Impacts of coexisting bronchial asthma on severe exacerbations in mild-to-moderate COPD: results from a national database

Directory of Open Access Journals (Sweden)

Lee H

2016-04-01

Full Text Available Hyun Lee,1 Chin Kook Rhee,2 Byung-Jae Lee,3 Dong-Chull Choi,3 Jee-Ae Kim,4 Sang Hyun Kim,5 Yoolwon Jeong,6 Tae-Hyung Kim,7 Gyu Rak Chon,8 Ki-Suck Jung,9 Sang Haak Lee,10 David Price,11 Kwang Ha Yoo,12,* Hye Yun Park1,* 1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 2Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St Mary’s Hospital, College of Medicine, The Catholic University of Korea, 3Division of Allergy, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 4Pharmaceutical Policy Evaluation Research Team, Research Institution, Health Insurance Review and Assessment Service, 5Big Data Division, Health Insurance Review and Assessment Service, Seoul, 6Division of Chronic Disease Control, Korea Centers for Disease Control and Prevention, Osong, 7Division of Pulmonary and Critical Care Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Gyeonggi-do, 8Department of Pulmonary and Critical Care Medicine, Chungju Hospital, Konkuk University School of Medicine, Chungju City, 9Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Hallym University College of Medicine, Anyang, 10Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, St Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea; 11Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, UK; 12Division of Pulmonary, Allergy and Critical Care Medicine Department of Internal Medicine, Konkuk University School of Medicine, Seoul, South Korea *These authors contributed equally to this work Backround: Acute exacerbations are major drivers of COPD deterioration. However, limited data are available for the

Jõulukuine plaadisadu / Joosep Sang

Index Scriptorium Estoniae

Sang, Joosep

2005-01-01

Lühidalt eesti heliplaatidest: "Eesti hääled", "Hendrik Sal-Saller & Estonian Dream Big Band", "Ain Agan ja Tallinna Kammerorkester", "The Book's Burning", "Mu süda ärka üles", "Inimene õpib...", "You Stepped Out of a Dream", "Andke tagasi maa", "Jesli ljubish, naidi..."

Docetaxel-loaded multilayer nanoparticles with nanodroplets for cancer therapy

Directory of Open Access Journals (Sweden)

Oh KS

2016-03-01

Full Text Available Keun Sang Oh,1,* Kyungim Kim,1,* Byeong Deok Yoon,1 Hye Jin Lee,1 Dal Yong Park,1 Eun-yeong Kim,1 Kiho Lee,1 Jae Hong Seo,2 Soon Hong Yuk1,2 1College of Pharmacy, Korea University, Sejong, 2Biomedical Research Center, Korea University Guro Hospital, Guro-gu, Seoul, Republic of Korea *These authors contributed equally to this work Abstract: A mixture of docetaxel (DTX and Solutol® HS 15 (Solutol transiently formed nanodroplets when it was suspended in an aqueous medium. However, nanodroplets that comprised DTX and Solutol showed a rapid precipitation of DTX because of their unstable characteristics in the aqueous medium. The incorporation of nanodroplets that comprised DTX and Solutol through vesicle fusion and subsequent stabilization was designed to prepare multilayer nanoparticles (NPs with a DTX-loaded Solutol nanodroplet (as template NPs core for an efficient delivery of DTX as a chemotherapeutic drug. As a result, the DTX-loaded Solutol nanodroplets (~11.7 nm were observed to have an increased average diameter (from 11.7 nm to 156.1 nm and a good stability of the hydrated NPs without precipitation of DTX by vesicle fusion and multilayered structure, respectively. Also, a long circulation of the multilayer NPs was observed, and this was due to the presence of Pluronic F-68 on the surface of the multilayer NPs. This led to an improved antitumor efficacy based on the enhanced permeation and retention effect. Therefore, this study indicated that the multilayer NPs have a considerable potential as a drug delivery system with an enhanced therapeutic efficacy by blood circulation and with low side effects. Keywords: multilayer nanoparticles, Solutol, Pluronic F-68, docetaxel, cancer therapy

Case report

African Journals Online (AJOL)

ebutamanya

7 sept. 2015 ... Il consiste en l'injection d'une quantité de sang autologue dans l'espace péridurale ... Le SPPL peut compliquer tous les types de ponctions durales, qu'il s'agisse ... un rôle activateur de la coagulation sur le sang injecté [5].

The Effect of Selected Cleaning Techniques on Berkshire Lee Marble: A Scientific Study at Philadelphia City Hall

Science.gov (United States)

Mossotti, Victor G.; Eldeeb, A. Raouf; Fries, Terry L.; Coombs, Mary Jane; Naude, Virginia N.; Soderberg, Lisa; Wheeler, George S.

2002-01-01

This report describes a scientific investigation of the effects of eight different cleaning techniques on the Berkshire Lee marble component of the facade of the East Center Pavilion at Philadelphia City Hall; the study was commissioned by the city of Philadelphia. The eight cleaning techniques evaluated in this study were power wash (proprietary gel detergent followed by water rinse under pressure), misting (treatment with potable, nebulized water for 24-36 hours), gommage (proprietary Thomann-Hanry low-pressure, air-driven, small-particle, dry abrasion), combination (gommage followed by misting), Armax (sodium bicarbonate delivered under pressure in a water wash), JOS (dolomite powder delivered in a low-pressure, rotary-vortex water wash), laser (thermal ablation), and dry ice (powdered-dry-ice abrasion delivered under pressure). In our study approximately 160 cores were removed from the building for laboratory analysis. We developed a computer program to analyze scanning-electron-micrograph images for the microscale surface roughness and other morphologic parameters of the stone surface, including the near-surface fracture density of the stone. An analysis of more than 1,100 samples cut from the cores provided a statistical basis for crafting the essential elements of a reduced-form, mixed-kinetics conceptual model that represents the deterioration of calcareous stone in terms of self-organized soiling and erosion patterns. This model, in turn, provided a basis for identifying the variables that are affected by the cleaning techniques and for evaluating the extent to which such variables influence the stability of the stone. The model recognizes three classes of variables that may influence the soiling load on the stone, including such exogenous environmental variables as airborne moisture, pollutant concentrations, and local aerodynamics, and such endogenous stone variables as surface chemistry and microstructure (fracturing, roughness, and so on). This study

Social networks and inference about unknown events: A case of the match between Google’s AlphaGo and Sedol Lee

Science.gov (United States)

Bae, Jonghoon; Cha, Young-Jae; Lee, Hyungsuk; Lee, Boyun; Baek, Sojung; Choi, Semin

2017-01-01

This study examines whether the way that a person makes inferences about unknown events is associated with his or her social relations, more precisely, those characterized by ego network density that reflects the structure of a person’s immediate social relation. From the analysis of individual predictions over the Go match between AlphaGo and Sedol Lee in March 2016 in Seoul, Korea, this study shows that the low-density group scored higher than the high-density group in the accuracy of the prediction over a future state of a social event, i.e., the outcome of the first game. We corroborated this finding with three replication tests that asked the participants to predict the following: film awards, President Park’s impeachment in Korea, and the counterfactual assessment of the US presidential election. Taken together, this study suggests that network density is negatively associated with vision advantage, i.e., the ability to discover and forecast an unknown aspect of a social event. PMID:28222114

A multivariate assessment of the coral ecosystem health of two embayments on the lee of the island of Hawai'i

Energy Technology Data Exchange (ETDEWEB)

Parsons, Michael L. [Marine Science Department, University of Hawai' i at Hilo, Hilo, HI 96720 (United States)], E-mail: mparsons@fgcu.edu; Walsh, William J. [Division of Aquatic Resources, Department of Land and Natural Resources, Kailua-Kona, HI 96740 (United States); Settlemier, Chelsie J.; White, Darla J.; Ballauer, Josh M.; Ayotte, Paula M.; Osada, Kara M. [Marine Science Department, University of Hawai' i at Hilo, Hilo, HI 96720 (United States); Carman, Brent [Division of Aquatic Resources, Department of Land and Natural Resources, Kailua-Kona, HI 96740 (United States)

2008-06-15

Four coral-dominated coastal sites within two embayments (Kealakekua Bay and Honokohau Bay) on the lee of the island of Hawai'i were studied to assess evidence of anthropogenic impacts in these relatively pristine locales. Nutrient-loading parameters were analyzed in relation to benthic composition data. Statistically, there were significant positive relationships between nitrate + nitrite, silicate, and ammonium with the abundance of macroalgae, coralline algae, and dead coral, and between {delta}{sup 15}N and dead coral abundance. The north outside site of Kealakekua Bay and the south outside site of Honokohau Bay appear to be most impacted by nutrient-loading factors in each bay, respectively. Comparisons with past nutrient data indicate that nutrient inputs have increased to the two bays, and that early impacts of these increased loadings are evident. It is predicted that at current nutrient-loading rates, the north sites of Kealakekua Bay and the south sites of Honokohau Bay will exhibit evidence of further degradation in future years.

Embodied Rhythm: Commentary on "The Contribution of Anthropometric Factors to Individual Differences in the Perception of Rhythm" by Neil P. McAngus Todd, Rosanna Cousins, and Christopher S. Lee

Directory of Open Access Journals (Sweden)

Bruno H. Repp

2007-01-01

Full Text Available Todd, Cousins, and Lee (2007 have presented some intriguing data suggesting that body size, as measured by standard anthropometric indices, is related to the preferred beat period in a perceptual task. Curiously, however, they did not find a significant sex difference, even though the women in their sample were clearly smaller than the men. Another recent study of preferred spontaneous tempo (McAuley et al., 2006 likewise failed to find a sex difference in a large sample of young adults. It is unclear why body size should have an effect only within each sex group.

Margem de segurança do meloxicam em cães: efeitos deletérios nas células sangüíneas e trato gastrintestinal Margin of safety of meloxicam in dogs: deleterious effects on blood cells and gastrointestinal tract

Directory of Open Access Journals (Sweden)

Marilac Maria Arnaldo Alencar

2003-06-01

Full Text Available Este trabalho investigou a margem de segurança do inibidor COX-2, meloxicam, em cães, enfocando seus efeitos deletérios nas células sangüíneas e no trato gastrintestinal. Para tanto, após uma avaliação clínico-laboratorial, os cães foram distribuídos nos seguintes grupos: I (placebo; n= 3, II (piroxicam; 1,0mg kg-1; n= 5, III (meloxicam; 0,2mg kg-1; n= 5, IV (meloxicam;1,0mg kg-1; n= 5 e V (meloxicam; 2,0mg kg-1; n= 5. Os fármacos foram usados, por via oral, por 16 dias. No 17º dia, repetiu-se o hemograma completo e, então, procedeu-se a eutanásia seguida pela necrópsia. No grupo I, não houve alterações dignas de nota. No grupo II, todos os cães apresentaram episódios moderados de vômito e diarréia. O perfil celular sangüíneo não foi significativamente modificado. Em dois cães, houve redução no hematócrito e na hemoglobina. Na necropsia, observaram-se focos hemorrágicos e lesões gastriduodenais moderadas. A análise microscópica revelou a presença de gastrite e enterite ulcerativa. No grupo III, quatro cães (80% apresentaram vômito e diarréia, sem alteração no perfil celular sangüíneo. Na análise macroscópica, observaram-se lesões brandas na mucosa gástrica e focos hemorrágicos no duodeno em quatro cães. Na histopatologia, observaram-se lesões sugestivas de discreta gastroenterite. No grupo IV, os cinco cães tiveram vômito e diarréia sanguinolenta. Quatro deles (80% apresentaram anemia (p This study investigated the margin of safety of the COX-2e inhibitor, meloxicam on blood cells and gastrointestinal tract of dogs. After a clinical and laboratorial examination, the dogs were distributed in the following groups: I (placebo; n=3, II (piroxicam: 1.0mg kg-1; n=5, III (meloxicam: 0.2mg kg-1; n=5, IV (meloxican: 1.0mg kg-1; n=5 and V (meloxican: 2.0mg kg-1; n=5. The drugs were given orally for 16 days. On the 17th day the complete hemogram was repeated and the euthanasia and necropsy were then

Pharmacological study of radioactive-gold colloid transport by blood and by serous exudate; Contribution a l'etude pharmacologique du transport des colloides d'or radioactif par le sang et les exsudats sereux

Energy Technology Data Exchange (ETDEWEB)

Rousselet, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1966-06-01

After giving the essential physico-chemical properties of the colloids, the author considers the biological role of these substances and, in connection with their transport by the blood, their capture by elements of the reticula-endothelial system. A summary is given of present knowledge concerning the role of serous proteins in the transport of substances, particularly that of radio-active colloidal gold. The blood fractions which can take part in colloidal gold transport are the red blood corpuscles, the leukocytes and histiocytic elements as well as the plasma. The radioactive distribution in these various fractions is obtained by autoradiography of blood sediments. After showing the importance of the role of the plasma in radioactive particle transport, the author, describes the attempts made to detect a possible of colloidal gold 198 on the various serous proteins using various methods of separation. The ''in vitro'' and ''in vivo'' bonds between colloidal gold-198 particles and either the serous proteins or healthy specimens or the effusion liquids of pathological origin in man, or due to an experimental inflammation with carregenin in the rat, have been studied. The bonding appears to be effective because of the protective macromolecular layer formed by the gelatine. The different positions of the colloidal grains on the electrophoregram can only be explained by their different physico-chemical characteristics. Gold in the ionic form, on the other hand, is combined only with the albumen is the amount metal present does not exceed a certain value. (author) [French] Apres avoir enonce les proprietes physicochimiques essentielles des colloides nous etudions le devenir biologique de ces substances et, en relation avec leur transport par le sang, leur captation par les elements du Systeme Reticulo-Endothelial. Nous resumons les connaissances acquises jusqu'alors sur le role des proteines seriques dans le transport des substances et particulierement dans le

Assessment of the Total Body Burden of Caesium-137 in Humans by the Analysis of Blood; Determination de la Charge Corporelle de Cesium 137 chez l'Homme, par Analyse Du Sang; 041e 041f 0420 0415 0414 ; Evaluacion de la Carga Corporal Total de Cesio-137 en el Hombre por Analisis de Sangre

Energy Technology Data Exchange (ETDEWEB)

Yamagata, N. [Institute of Public Health, Tokyo (Japan)

1964-11-15

'anthropogammametres et ceux-ci sont des appareils fixes; dans ces conditions, il n'est pas facile de determiner la charge moyenne pour une population. Toutefois, la collecte de tissus musculaires ainsi preleves est une operation compliquee, en outre, cette methode n'est pas satisfaisante, car il faudrait en realite posseder des echantillons preleves immediatement apres la mort. Etant donne que l'on a seulement besoin de donnees susceptibles d'etre utilisees pour determiner la charge moyenne de cesium 137 pour une population donnee et qu'il n'est pas necessaire de connaitre les valeurs individuelles, il suffit d'avoir des echantillons globaux provenant du plus grand nombre possible d'individus. Aussi a-t-on pense que des echantillons de sang pur pourraient remplacer le mieux les tissus musculaires, parce qu'il existe deja un reseau de ramassage du sang, ramife dans tout le Japon (notamment 47 banques du sang autorisees et une centaine d'hopitaux). On procede deja, a l'Institut national de la sante, de Tokyo, a des enquetes par sondages pour verifier les caracteristiques du sang citrate. Environ 500 ampoules sont examinees chaque annee; cet echantillon represente plus de trois millions de donneurs repartis dans l'ensemble du pays. Pour cette verification, on n'utilise que la moitie du contenu des ampoules et on met en stock l'autre moitie pour qu'elle serve a preparer un echantillon global en vue de la determination de la charge moyenne de cesium 137, Le sang etant incinere, on dose le cesium stable contenu dans les cendres par une methode d'activation par les neutrons. Des resultats, on deduit le rapport entre la concentration de cette substance dans le sang pur et la quantite totale contenue dans le corps (1,4 mg pour un homme de 70 kg). Ce chiffre sera le meme que pour le cesium 137 dans des conditions d'equilibre. On a compare les resultats obtenus depuis juin 1963 par cette methode avec les resultats trouves par l'analyse de tissus musculaires pendant la meme periode. On a constate

Cardiopulmonary bypass in Jehovah's Witnesses | Frimpong ...

African Journals Online (AJOL)

Il reprouve également les transfusions autogouses s'il n'y a pas un rapport continue entre la circulation et sang autologous. Donc, en ce qui concerne le Témoin de Jéhovah, c'est nécessaire d'adopter des méthodes qui vont éviter la transfusion du sang hétérologous dans ces cas facultatifs. Nous faisons un rapport sur ...

Research

African Journals Online (AJOL)

abp

22 avr. 2014 ... autres des Centres Provinciaux de Transfusion Sanguine (CPTS), promouvoir le don volontaire et non rémunéré de sang font partie des stratégies utilisées. Cependant, l'offre est encore loin de couvrir la demande en sang. A. Kisangani, ville du nord-est avec une population estimée à 900 000 habitants, le ...

Chronic depression treated successfully with novel taping therapy: a new approach to the treatment of depression

Directory of Open Access Journals (Sweden)

Han CH

2016-06-01

Full Text Available Chang Hyun Han,1,* Hwa Soo Hwang,2,* Young Joon Lee,3 Sang Nam Lee,4 Jane J Abanes,5 Bong Hyo Lee6 1Clinical Research Division, Korea Institute of Oriental Medicine, Daejeon, 2Chims-Saengvit Oriental Medicine Clinic, Seoul, 3Department of Preventive Korean Medicine, 4Department of Qigong, College of Korean Medicine, Daegu Haany University, Gyeongsangbuk-do, South Korea; 5Daniel K Inouye Graduate School of Nursing, Uniformed Services University of the Health Sciences, Bethesda, MD, USA; 6Department of Acupuncture, Moxibustion and Acupoint, College of Korean Medicine, Daegu Haany University, Daegu, South Korea *These authors contributed equally to this work Introduction: Despite improved research in the treatment, depression remains difficult to treat. Till date, successful treatment of depression using taping therapy has not been known yet. We report cases where patients with severe depressive symptoms were successfully treated by taping therapy, a new approach.Methods: In case 1, a patient was taking several psychiatric medications for 10 years and admitted often to the psychiatric hospital with a leaning head, flexible legs, and nearly closed eyes; in case 2, a patient after a hysterectomy complained with heart palpitations, depressive- and anxiety-like behaviors, insomnia, and gastrointestinal problems; and in case 3, a patient with complaints of adverse effects from antidepressant medications had suicidal thoughts frequently. The medical tapes were placed on acupoints, trigger points, and pain points found by finger pressing examination in the chest, sides, and upper back of the patients.Results: In case 1, the patient started weeping immediately after the first treatment. He discontinued psychiatric drugs and returned to baseline functioning after 2 months. In case 2, the patient felt at ease showing decreased palpitation immediately after the first treatment, and after 1 week, she quit medications. In case 3, the patient experienced a

Enzyme-responsive doxorubicin release from dendrimer nanoparticles for anticancer drug delivery

Directory of Open Access Journals (Sweden)

Lee SJ

2015-08-01

Full Text Available Sang Joon Lee,1,* Young-Il Jeong,2,* Hyung-Kyu Park,3 Dae Hwan Kang,2,4 Jong-Suk Oh,3 Sam-Gyu Lee,5 Hyun Chul Lee31Department of Biomedical Sciences, Chonnam National University Medical School, Gwangju, 2Biomedical Research Institute, Pusan National University Hospital, Busan, 3Department of Microbiology, Chonnam National University Medical School, Gwangju, 4Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Gyeongnam, 5Department of Physical and Rehabilitation Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea*These authors contributed equally to this workBackground: Since cancer cells are normally over-expressed cathepsin B, we synthesized dendrimer-methoxy poly(ethylene glycol (MPEG-doxorubicin (DOX conjugates using a cathepsin B-cleavable peptide for anticancer drug targeting.Methods: Gly-Phe-Leu-Gly peptide was conjugated with the carboxylic acid end groups of a dendrimer, which was then conjugated with MPEG amine and doxorubicin by aid of carbodiimide chemistry (abbreviated as DendGDP. Dendrimer-MPEG-DOX conjugates without Gly-Phe-Leu-Gly peptide linkage was also synthesized for comparison (DendDP. Nanoparticles were then prepared using a dialysis procedure.Results: The synthesized DendGDP was confirmed with 1H nuclear magnetic resonance spectroscopy. The DendDP and DendGDP nanoparticles had a small particle size of less than 200 nm and had a spherical morphology. DendGDP had cathepsin B-sensitive drug release properties while DendDP did not show cathepsin B sensitivity. Further, DendGDP had improved anticancer activity when compared with doxorubicin or DendDP in an in vivo CT26 tumor xenograft model, ie, the volume of the CT26 tumor xenograft was significantly inhibited when compared with xenografts treated with doxorubicin or DendDP nanoparticles. The DendGDP nanoparticles were found to be relatively concentrated in the tumor tissue and

Effect of tiotropium on lung function decline in early-stage of chronic obstructive pulmonary disease patients: propensity score-matched analysis of real-world data

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Lee HY

2015-10-01

Full Text Available Ha Youn Lee,1,2 Sun Mi Choi,1,2 Jinwoo Lee,1,2 Young Sik Park,1,2 Chang-Hoon Lee,1,2 Deog Kyeom Kim,2,3 Sang-Min Lee,1,2 Ho Il Yoon,2,4 Jae-Joon Yim,1,2 Young Whan Kim,1,2 Sung Koo Han,1,2 Chul-Gyu Yoo1,2 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; 2Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; 3Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea; 4Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea Background: Tiotropium failed to slow the annual rate of forced expiratory volume in 1 second (FEV1 decline in chronic obstructive pulmonary disease (COPD patients with <70% predicted FEV1. However, the rate of FEV1 decline is known to be faster at early stages, which suggests that the effects of tiotropium may be more prominent in early-stage of COPD patients. The aim of this study was to test the hypothesis that tiotropium modifies the rate of FEV1 decline in COPD patients with an FEV1≥70%.Methods: We retrospectively reviewed the records of COPD patients diagnosed between January 1, 2004, and July 31, 2012, at Seoul National University Hospital, Seoul National University Bundang Hospital, and Seoul Metropolitan Government-Seoul National University Boramae Medical Center. The inclusion criteria were as follows: age ≥40 years, postbronchodilator (BD FEV1≥70% of predicted and FEV1/FVC (forced vital capacity <0.70, and spirometry more than two times at certain times of the year. Conversely, the exclusion criteria were as follows: asthma, lung cancer, pulmonary tuberculosis, pulmonary resection, or long-term use of a short-acting muscarinic antagonist. The annual lung function decline in patients using tiotropium was compared with that in patients not

Eighth Mendeleyev Congress on General and Applied Chemistry USSR.

Science.gov (United States)

1960-06-27

the congress a memorable gift - 9- 1- a silk -embroidered portrait of D.I. Mendeleyev. At the subsequent plenary sessions of the congress the...of zirconium and iron (E.M. Braynina); titanium and silicon (A.N. Nesmeyanov, O.V. Nogina, Yu.P. Kudryavtsev); aluminum trlalkyls (L.I. Zakharkin...of ™tr tents. __,,,__ M.Ye. Pronln, in his paper ««iffeet of Fertilizers on Yields of Corn and Amelioration of Its Quality«, called attention

Multifunctional Poly(2,5-benzimidazole)/Carbon Nanotube Composite Films

Science.gov (United States)

2010-01-01

Multifunctional Poly(2,5- benzimidazole )/Carbon Nanotube Composite Films JI-YE KANG,1 SOO-MI EO,1 IN-YUP JEON,1 YEONG SUK CHOI,2 LOON-SENG TAN,3 JONG...molecular-weight poly(2,5- benzimidazole ) (ABPBI). ABPBI/carbon nanotube (CNT) compo- sites were prepared via in situ polymerization of the AB-monomer in the...polymerization; multiwalled carbon nanotube (MWCNT); nano- composites; poly(2,5- benzimidazole ); (ABPBI); polycondensa- tion; poly(phosphoric acid); single-walled

Effect of self-assembled peptide–mesenchymal stem cell complex on the progression of osteoarthritis in a rat model

Directory of Open Access Journals (Sweden)

Kim JE

2014-05-01

Full Text Available Ji Eun Kim,1 Sang Mok Lee,2 Soo Hyun Kim,1 Phil Tatman,3 Albert O Gee,4 Deok-Ho Kim,3,5 Kyung Eun Lee,6 Youngmee Jung,1 Sang Jun Kim21Biomaterials Research Center, Korea Institute of Science and Technology, Seoul, South Korea; 2Department of Physical and Rehabilitation Medicine, Samsung Medical Center, Seoul, South Korea; 3Department of Bioengineering, 4Department of Orthopaedics and Sports Medicine, 5Institute for Stem Cell and Regenerative Medicine and Center for Cardiovascular Biology, University of Washington, Seattle, WA, USA; 6Advanced Analysis Center, Korea Institute of Science and Technology, Seoul, South KoreaPurpose: To evaluate the efficacy of mesenchymal stem cells (MSCs encapsulated in self-assembled peptide (SAP hydrogels in a rat knee model for the prevention of osteoarthritis (OA progression.Materials and methods: Nanostructured KLD-12 SAPs were used as the injectable hydrogels. Thirty-three Sprague Dawley rats were used for the OA model. Ten rats were used for the evaluation of biotin-tagged SAP disappearance. Twenty-three rats were divided into four groups: MSC (n=6, SAP (n=6, SAP-MSC (n=6, and no treatment (n=5. MSCs, SAPs, and SAP-MSCs were injected into the knee joints 3 weeks postsurgery. Histologic examination, immunofluorescent staining, measurement of cytokine levels, and micro-computed tomography analysis were conducted 6 weeks after injections. Behavioral studies were done to establish baseline measurements before treatment, and repeated 3 and 6 weeks after treatment to measure the efficacy of SAP-MSCs.Results: Concentration of biotinylated SAP at week 1 was not significantly different from those at week 3 and week 6 (P=0.565. Bone mineral density was significantly lower in SAP-MSC groups than controls (P=0.002. Significant differences in terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick-end labeling staining between the control group and all other groups were observed. Caspase-8, tissue inhibitor of

1514-IJBCS-Article-Melima Mamatchi

African Journals Online (AJOL)

KODJIO NORBERT

déterminées dans le sang humain à Gbodjomé (zone de référence) et à Kpémé où les populations consomment des aliments ... Cd et du Pb, qui provoquent un stress oxydatif dans l'organisme humain qui présente une disponibilité à la bioaccumulation de ces ..... reins, le foie, le système nerveux, le sang et peuvent être ...

Research

African Journals Online (AJOL)

abp

28 avr. 2014 ... prévalence du portage asymptomatique du plasmodium chez les donneurs bénévoles de sang à Kisangani. Méthodes: Une étude transversale a été menée au Centre Provincial de Transfusion Sanguine à Kisangani du 1er Décembre 2012 au 31 Mars 2013 et a concerné 480 donneurs bénévoles de sang ...

Strategic Studies Quarterly. Volume 9, Number 2. Summer 2015

Science.gov (United States)

2015-01-01

Leadership Monitor 31 (Winter 2010): http://media .hoover.org/sites/default/files/documents/CLM31JCM.pdf. 41. Nicola Horsburgh, "Change and Innovation...Vietnamese president Truong Tan Sang promoted partnership with China in a wide range of fields, including people-to-people exchanges and economic...Truong Tan Sang of Vietnam, Stressing to Forge Ahead in the Overall Direction of the Development of China-Vietnam Relations," 15 October 2013, http

Kuula ka neid / Joosep Sang

Index Scriptorium Estoniae

Sang, Joosep

2009-01-01

Tutvustused : XXI Sajandi Orkester. Üheksa. Tallinn : XXISO, 2008. Illustraator. Minu keha. Tallinn : MTÜ ILL Produktsioon, 2008. Pastoraal. Helirännak põldudel ja heinamaadel. Tallinn : Eestimaa Looduse fond, 2008

PIERRE BOURDIEU, SANG JURU DAMAI

OpenAIRE

Krisdinanto, Nanang

2016-01-01

Pierre Bourdieu built his theoretical orientation as a solution to what he saw as a false opposition between objectivism and subjectivism; to quote Bourdieu: “absurd opposition between individual and society”. Bourdieu offered a point of view that emphasizes on duality in the relationship between agent and structure, as an alternative to the previously existing dualistic views. Bourdieu refers to his theoretical orientation as genetic structuralism, constructivist structuralism or structurali...

Kuula ka neid / Joosep Sang

Index Scriptorium Estoniae

Sang, Joosep

2009-01-01

Heliplaaditutvustused: Bullfrog Brown with Steve Lury. KWAQ Records, 2009; Grupa Janke Randalu. Live. [Saksamaa] : Jazz'n'Arts, 2008; Paha Polly. Ei jäägi üle muud... [Tartu] : Forward, 2008. Uutest heliplaatidest

Reorientando a identidade nacional em Native speaker, de Chang-rae Lee, e O sol se põe em São Paulo, de Bernardo Carvalho

Directory of Open Access Journals (Sweden)

Rex P. Nielson

2014-01-01

Full Text Available A comparative reading of the novels Native speaker (1995, by the North American writer Chang-rae Lee, and O sol se põe em São Paulo (2007, by Bernardo Carvalho, allows for a reevaluation of how minority identities have been constructed in the two American megalopolises New York and São Paulo. The plotlines of both nove ls hinge on the identity crisis of a second-generation Asian immigrant (from Korea in one case and Japan in the other who is seeking to negotiate his American identity (speaking in hemispheric terms in terms of his family‟s origin and language. However, despite the similar anxieties over assimilation present in both novels, they both reveal significant differences regarding the ways in which the United States and Brazil have responded to cultural difference even as they challenge national myths of inclusi on and belonging.

Una mirada crítico-hermenéutica a las representaciones sociales de la infancia a través de las imágenes plasmadas en la cartilla inicial de lectura Nacho lee: 1974-2011

OpenAIRE

Álvarez Torres, Jair Hernando; Naranjo Loaiza, Jenyffer

2013-01-01

This article approaches, from a critical-hermeneutical view, the role played by the teaching manual in the childhood scholarity and its influence on the representations and the imaginaries of children in Colombia between 1974 and 2011. In order to do so, the text for reading initiation Nacho lee was chosen because it is a manual that still exists in the mind and in the imaginaries of Colombians and also is a text that is easy to get in the market, a condition n...

Perfil bioquímico de algumas enzimas no plasma sangüíneo de potras da raça Brasileiro de Hipismo (BH criadas em Colina, Estado de São Paulo

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Fernando José Benesi

2009-08-01

Full Text Available Com o propósito de avaliar o perfil bioquímico de algumas enzimas, em potras sadias da raça BH (Brasileiro de Hipismo, utilizaram-se 380 amostras de plasma sangüíneo colhidas de 19 animais desde o nascimento até 24 meses de vida. Na análise dos resultados evidenciou-se que os valores médios das enzimas FA (fosfatase alcalina e CK (creatina quinase foram máximos entre o nascimento e 24 horas de vida (FA-1995.50 UI/ ; CK-189.13UI/L, enquanto que para a LD (lactato desidrogenase e GGT (gama glutamiltransferase as maiores magnitudes ocorreram, respectivamente, entre 3 e 4 dias (LD-479.11UI/L e aos 10 dias de idade (GGT-18.70UI/L. As FA, CK, LD e GGT, mostraram diminuições dos valores médios, respectivamente, até 6 meses (FA-323.50UI/L, 20 dias (CK-51UI/ L, 19 meses (LD-214.00UI/L e 4 meses (GGT-11.40UI/L estabilizando-se a seguir, com pequenas variações. A atividade da AST (aspartato aminotransferase que foi mínima logo após o nascimento (AST- 43.38UI/L, aumentou até os sete dias de vida (AST-110.89UI/L, e a seguir diminuiu progressivamente, com pequenas oscilações, até o final do estudo. Todas as enzimas avaliadas sofreram variações influenciadas pelo fator etário, particularmente no período inicial de vida dos animais estudados.

Level II scour analysis for Bridge 38 (JERITH0020038) on Town Highway 20, crossing the Lee River, Jericho, Vermont

Science.gov (United States)

Wild, Emily C.; Degnan, James R.

1997-01-01

This report provides the results of a detailed Level II analysis of scour potential at structure JERITH00200038 on Town Highway 20 crossing the Lee River, Jericho, Vermont (figures 1–8). A Level II study is a basic engineering analysis of the site, including a quantitative analysis of stream stability and scour (U.S. Department of Transportation, 1993). Results of a Level I scour investigation also are included in Appendix E of this report. A Level I investigation provides a qualitative geomorphic characterization of the study site. Information on the bridge, obtained from Vermont Agency of Transportation (VTAOT) files, was compiled prior to conducting Level I and Level II analyses and is found in Appendix D. The site is in the Green Mountain section of the New England physiographic province and the Champlain section of the St. Lawrence physiographic province in northwestern Vermont. The 12.9-mi2 drainage area is in a predominantly rural and forested basin. In the vicinity of the study site, the surface cover on the upstream and downstream right overbank is pasture while the immediate banks have dense woody vegetation. The surface cover on the upstream and downstream left overbank is forested. In the study area, the Lee River has an incised, sinuous channel with a slope of approximately 0.02 ft/ft, an average channel top width of 89 ft and an average bank height of 14 ft. The channel bed material ranges from sand to boulder with a median grain size (D50) of 45.9 mm (0.151 ft). The geomorphic assessment at the time of the Level I and Level II site visit on July 2, 1996, indicated that the reach was stable. The Town Highway 20 crossing of the Lee River is a 49-ft-long, one-lane bridge consisting of a steel through truss span (Vermont Agency of Transportation, written communication, December 12, 1995). The opening length of the structure parallel to the bridge face is 44 ft. The bridge is supported by vertical, concrete abutments with wingwalls. The channel is

2467-IJBCS-Article-Youzan Ferdinand Djohan

African Journals Online (AJOL)

hp

Laboratory of Biochemistry, cord blood was used to assay the glucose by enzymatic method with glucose oxidase. It appears at ... Prélèvements. Deux prélèvements de sang ont été effectués chez chaque nouveau-né dix minutes après sa naissance. Un prélèvement capillaire au talon et un prélèvement de sang veineux au.

Donor Blood Procurement and Utilisation at the University of Benin ...

African Journals Online (AJOL)

Les dossiers du service de la transfusion sanguine de l\\'hôpital ont été étudiés pour identifier les méthodes d\\'obtention et d\\'utilisation du sang à partir du 1er janvier 2000 jusqu\\'au 31 décembre 2002. Au total, 11,021 unités de sang ont été obtenu dans le service de transfusion sanguine au cours de la période.

Progress in Medicine

CERN Multimedia

Bernard,J

1980-01-01

Le Prof.Jean Bernard a fait ses études à la faculté à Paris et est médecin des hôpitaux et directeur du laboratoire de recherche expérimentale sur la leucémie et les maladies du sang. Il parle du developpement de la recherche médicale et connaissances sur les causes et traitements des maladies du sang et en particulier sur la leucémie

Efeitos da farinha de folhas de mandioca sobre a peroxidação lipídica, o perfil lipídico sangüíneo e o peso do fígado de ratos Effects of cassava leaf flour on lipidic peroxidation, blood lipidic profile and liver weight of rats

Directory of Open Access Journals (Sweden)

Daniela Séfora de Melo

2007-04-01

Full Text Available Sabe-se que polifenóis e saponinas apresentam efeitos antioxidante e hipolipidêmico, respectivamente. Como folhas de mandioca contêm estas substâncias, foi investigado o efeito de dietas contendo a farinha de folhas de mandioca (FFM sobre a peroxidação lipídica, o perfil lipídico sangüíneo e o peso do fígado de ratos. Para isto, folhas maduras de mandioca (Manihot esculenta Crantz cv. Cacao foram secas em estufa ventilada a 30-35 ºC e trituradas sem os pecíolos. Um ensaio biológico, com 32 ratos machos Wistar, foi conduzido por um período de 7 semanas com quatro tratamentos: dieta controle e dietas contendo 5%, 10% e 15% de FFM, sendo todas suplementadas com 1% de colesterol. As dietas se apresentaram isoenergéticas e contendo os mesmos níveis de proteína digestível e fibras. Foi observado que dietas contendo FFM não apresentaram efeitos significativos sobre o perfil lipídico sangüíneo e sobre as variáveis de desempenho, mas contribuiram para o aumento no peso do fígado. Já as dietas contendo 10% e 15% de FFM foram associadas à redução nos teores plasmáticos de substâncias reativas ao ácido tiobarbitúrico.It is well known that polyphenols and saponins present antioxidant and hypolipidemic effects, respectively. As cassava leaves contains these substances, the effects of diets supplemented with cassava leaf flour (CLF on lipidic peroxidation, blood lipid profile and liver weight of rats were investigated. Therefore, ripe cassava leaves (Manihot esculenta Crantz cv. Cacao were dried in a ventilated oven at 30-35 ºC and ground without the petioles. A biological assay was conducted during 7 weeks with 32 Wistar male rats submitted to four treatments: control diet and diets containing 5%, 10% and 15% CLF, all supplemented with 1% cholesterol. Diets were isoenergetic and contained the same levels of digestible protein, and fibers. It was observed that diets containing CLF presented no significant effect on blood

Novo sistema de cardioplegia sangüínea em cirurgia de cardiopatia congênita New delivery system for pediatric blood cardioplegia

Directory of Open Access Journals (Sweden)

Pedro R Salerno

1995-09-01

Full Text Available O objetivo do presente estudo é apresentar um sistema de cardioplegia sangüínea para cirurgia de cardiopatia congênita. Foram analisados, prospectivamente, 71 pacientes com 10.12 kg em média, 34 eram do sexo feminino e a idade média foi de 2,1 anos. Da linha arterial, passando por um trocador de calor, aspiramos para uma seringa de 50 cc sangue a 8ºc, a qual é conectada a outra seringa de 10 cc com uma solução decimal de potássio, através de duas torneirinhas. A mistura da solução decimal (3 ml com 47 ml de sangue a 8o C origina uma solução de sangue com 15 meq/1 de potássio. Esta solução é infundida na raiz da aorta, de acordo com o peso do paciente (10 cc/kg. Em todos obtivemos parada cardioplégica. O tempo médio de extracorpórea foi de 87,2 minutos e de pinçamento aórtico, de 60,7 minutos. Treze pacientes evoluíram para óbito, 6 por falência miocárdica, 3 por síndrome de baixo débito, 2 com arritmia, 1 com falência renal e 1 com coagulopatia. Os 58 demais pacientes receberam alta hospitalar sem complicações. Em conclusão, este método mostrou ser eficiente na preservação miocárdica e com baixa morbi-mortalidadeThe purpose of this study is to present a simple Delivery System of Blood Cardioplegia for myocardial preservation during congenital cardiac operation. We prospectively analysed 71 patients (pts with 10/12 kg of body mean weight, 34 were female and mean age was 2/1 years. From the arterial line, passing through a mini heat exchanger, blood at 8 C is aspirated to a 50 cc syringe, which is conected to a 10 cc syringe with a KCL + decimal solución using 2 stopcocks. The mixture originates a cold blood with 15 mEq/l of KCL + that is infused into the aortic root, according to the pts weight (10 cc/kg. In all pts cardiac arrest was obtained. The mean extracorporeal circulation time and crossclamping was 87.2 and 60.7 min. All pts recovered sinus rhythm with good ventricular function. Thirteen patients

Avaliação do suprimento sangüíneo vascular pulmonar nos portadores de atresia pulmonar com comunicação interventricular e artérias colaterais sistêmico-pulmonares Assessment of the pulmonary vascular blood supply in patients with pulmonary atresia, ventricular septal defect, and aortopulmonary collateral arteries

Directory of Open Access Journals (Sweden)

Ulisses Alexandre Croti

2005-01-01

Full Text Available OBJETIVO: Analisar as características morfométricas das artérias pulmonares centrais e artérias colaterais sistêmico-pulmonares, avaliando a morfologia do suprimento sangüíneo vascular pulmonar, procurando estabelecer suas implicações no tratamento cirúrgico. MÉTODO: Entre janeiro/1990 e junho/2001, foram estudados 40 pacientes, incluíndo-se os que apresentavam estudo cineangiocardiográfico completo e prévio à primeira intervenção cirúrgica. Analisaram-se as características morfométricas das artérias pulmonares centrais e artérias colaterais sistêmico-pulmonares, assim como a distribuição da irrigação sangüínea nos pulmões. Calcularam-se os índices arterial pulmonar (IAAPP, arterial colateral sistêmico-pulmonar (IACSP e arterial neopulmonar total (IANPT = IAAPP + IACSP. O tratamento cirúrgico foi considerado paliativo (TP, paliativo definitivo (TPD e definitivo (TD. RESULTADOS: O TP foi predominante. Não houve diferenças estatisticamente significantes entre os pacientes com TP, TPD e TD, em relação ao IAAPP, IACSP e IANPT. Comparando o IAAPP e o IACSP, não houve diferença entre os índices para o TD (p=0,4309, o IACSP foi maior que o IAAPP para o TP (p=0,0176 e descritivamente também maior para o TPD. O IANPT dos pacientes em TD foi maior que os em TP (p=0,0959. Foram identificados cinco subgrupos morfologicamente semelhantes, denominados: B1, B2, B3, B4 e B5. A mortalidade total foi de 17,5%. CONCLUSÃO: A morfologia do suprimento sangüíneo vascular pulmonar das artérias pulmonares centrais e artérias colaterais sistêmico-pulmonares mostrou-se soberana na orientação do tratamento cirúrgico. Independentemente da divisão didática em subgrupos, o TP foi predominante. A mortalidade não apresentou correlação com as características morfométricas.OBJECTIVE: To study the morphometric characteristics of the central pulmonary arteries and aortopulmonary collateral arteries by assessing the morphology

22nd September 2010 - Korean Minister of Education, Science and Technology J.-H. Lee signing the guest book and exchanging gifts with CERN Director-General R. Heuer and Head of International Relations F. Pauss; visiting ALICE exhibition with Collaboration Spokesperson J. Schukraft; accompanied throughout by Adviser R. Voss.

CERN Multimedia

Teams : M. Brice ; JC Gadmer

2010-01-01

22nd September 2010 - Korean Minister of Education, Science and Technology J.-H. Lee signing the guest book and exchanging gifts with CERN Director-General R. Heuer and Head of International Relations F. Pauss; visiting ALICE exhibition with Collaboration Spokesperson J. Schukraft; accompanied throughout by Adviser R. Voss.

Comparative Assessment of Health Workers Performance and The ...

African Journals Online (AJOL)

Le critère de sélection était antigène HBs (AgHBs) positif à l'issue d'un don de sang au Centre national de Transfusion Sanguine (CNTS). La prévalence du portage de l'Ag HBs chez les nouveaux donneurs de sang était de 7,06 %. L'âge moyen des patients était de 26,3 ans avec des extrêmes de 20 et 51 ans. Le sexratio ...

Dampak Ketidakhadiran Ibu Sebagai Tenaga Kerja Wanita (TKW Terhadap Perkembangan Psikologis Remaja

Directory of Open Access Journals (Sweden)

Lia Amalia

2010-12-01

Full Text Available Abstrak: Bagi remaja yang memiliki ibu TKW, dinamika psikologis yang terjadi dalam  proses  perkembangan  ini  menjadi  hal  yang  menarik  karena ketidakhadiran  ibu  sebagai  salah  satu  tokoh  sentral  yang  biasanya memiliki peran besar dalam perkembangan sang anak. Hasil dari riset ini adalah: pertama,keempat subjek merasakan kesedihan saat ditinggalkan oleh sang ibu pada awalnya (saat masih anak-anak, namun berangsurangsur tiga subjek (H, P, dan D bisa beradaptasi, hingga saat remaja dapat menerima keadaan tersebut. Hanya ada satu subjek (A yang sampai saat ini masih terus merasa sedih dengan kepergian ibunya, hal ini ada kaitannya dengan ketidaktersedian figur attachment pengganti sang ibu dari keluarga. Kedua, tiga subjek (A, H, dan Pmemiliki persepsi positif mengenai pekerjaan sang ibu sebagai TKW (pekerjaan mulia, halal,  sumber  keuangan,  pahlawan  keluarga,  dan  pahlawan  devisa sedangkan satu subjek (D menilai sebenarnya pekerjaan ibunya sebagai TKW kurang layak tetapi ini adalah pekerjaan yang halal. Ketiga, tiga subjek (H, P, dan D menemukan figur attachment pengganti setelah kepergian sang ibu dari keluarga. Sedangkan subjek A tidak menemukan figur attachment pengganti ibu dari pihak keluarga sehingga ia mencari figur attachment dari luar keluarga (sahabat A beserta keluarganya. (d  Self  esteem dipengaruhi  kuat  oleh  keharmonisan  keluarga.  Dari 4 subjek, hanya satu (P yang merasa bahwa keluarganya harmonis meskipun ibu bekerja sebagai TKW. 3 subjek lainnya (A, H, dan D menilai bahwa keluarga mereka tidak harmonis. Kondisi keluarga yang tidak harmonis tidak mendukung terbangunnya self-esteem yang positif sehingga bisa disimpulkan bahwa self-esteem dari aspek keluarga pada subjek A, H, dan D adalah negatif.

The effects of Hurricane Irene and Tropical Storm Lee on the bed sediment geochemistry of U.S. Atlantic coastal rivers

Science.gov (United States)

Horowitz, Arthur J.

2013-01-01

Hurricane Irene and Tropical Storm Lee, both of which made landfall in the U.S. between late August and early September 2011, generated record or near record water discharges in 41 coastal rivers between the North Carolina/South Carolina border and the U.S./Canadian border. Despite the discharge of substantial amounts of suspended sediment from many of these rivers, as well as the probable influx of substantial amounts of eroded material from the surrounding basins, the geochemical effects on the TOC), total nitrogen (TN), Zn, Se, Co, Cu, Pb, As, Cr, and total carbon (TC). As a group, these constituents tend to be associated either with urbanization/elevated population densities and/or wastewater/solid sludge. The limited number of significant sediment-associated chemical changes that were detected probably resulted from two potential processes: (1) the flushing of in-stream land-use affected sediments that were replaced by baseline material more representative of local geology and/or soils (declining concentrations), and/or (2) the inclusion of more heavily affected material as a result of urban nonpoint-source runoff and/or releases from flooded treatment facilities (increasing concentrations). Published 2013. This article is a U.S. Government work and is in the public domain in the USA.

Economic value of angling on the Colorado River at Lees Ferry: Using secondary data to estimate the influence of seasonality

Science.gov (United States)

Bair, Lucas S.; Rogowski, David L.; Neher, Christopher

2016-01-01

Glen Canyon Dam (GCD) on the Colorado River in northern Arizona provides water storage, flood control, and power system benefits to approximately 40 million people who rely on water and energy resources in the Colorado River basin. Downstream resources (e.g., angling, whitewater floating) in Glen Canyon National Recreation Area (GCNRA) and Grand Canyon National Park are impacted by the operation of GCD. The GCD Adaptive Management Program was established in 1997 to monitor and research the effects of dam operations on the downstream environment. We utilized secondary survey data and an individual observation travel cost model to estimate the net economic benefit of angling in GCNRA for each season and each type of angler. As expected, the demand for angling decreased with increasing travel cost; the annual value of angling at Lees Ferry totaled US$2.7 million at 2014 visitation levels. Demand for angling was also affected by season, with per-trip values of $210 in the summer, $237 in the spring, $261 in the fall, and $399 in the winter. This information provides insight into the ways in which anglers are potentially impacted by seasonal GCD operations and adaptive management experiments aimed at improving downstream resource conditions.

Effect of the protein corona on nanoparticles for modulating cytotoxicity and immunotoxicity

Directory of Open Access Journals (Sweden)

Lee YK

2014-12-01

Full Text Available Yeon Kyung Lee,1,* Eun-Ju Choi,2,* Thomas J Webster,3 Sang-Hyun Kim,4 Dongwoo Khang1 1Department of Molecular Medicine, School of Medicine, Gachon University, Incheon, South Korea; 2Division of Sport Science, College of Science and Technology, Konkuk University, Chungju, South Korea; 3Department of Chemical Engineering and Program in Bioengineering, Northeastern University, Boston, MA, USA; 4Department of Pharmacology, School of Medicine, Kyungpook National University, Daegu, South Korea *These authors contributed equally to this work Abstract: Although the cytotoxicity of nanoparticles (NPs is greatly influenced by their interactions with blood proteins, toxic effects resulting from blood interactions are often ignored in the development and use of nanostructured biomaterials for in vivo applications. Protein coronas created during the initial reaction with NPs can determine the subsequent immunological cascade, and protein coronas formed on NPs can either stimulate or mitigate the immune response. Along these lines, the understanding of NP-protein corona formation in terms of physiochemical surface properties of the NPs and NP interactions with the immune system components in blood is an essential step for evaluating NP toxicity for in vivo therapeutics. This article reviews the most recent developments in NP-based protein coronas through the modification of NP surface properties and discusses the associated immune responses. Keywords: nanostructured biomaterials, blood response, cytotoxicity, immunotoxicity, protein corona

Gold nanoparticles promote osteogenic differentiation in human adipose-derived mesenchymal stem cells through the Wnt/β-catenin signaling pathway

Directory of Open Access Journals (Sweden)

Choi SY

2015-07-01

Full Text Available Seon Young Choi,1 Min Seok Song,1 Pan Dong Ryu,1 Anh Thu Ngoc Lam,2 Sang-Woo Joo,2 So Yeong Lee1 1Laboratory of Veterinary Pharmacology, Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, 2Department of Chemistry, Soongsil University, Seoul, South Korea Abstract: Gold nanoparticles (AuNPs are attractive materials for use in biomedicine due to their physical properties. Increasing evidence suggests that several nanoparticles induce the differentiation of human mesenchymal stem cells into osteoblasts and adipocytes. In this study, we hypothesized that chitosan-conjugated AuNPs promote the osteogenic differentiation of human adipose-derived mesenchymal stem cells. For the evaluation of osteogenic differentiation, alizarin red staining, an alamarBlue® assay, and a quantitative real-time polymerase chain reaction analysis were performed. In order to examine specific signaling pathways, immunofluorescence and a western blotting assay were performed. Our results demonstrate that chitosan-conjugated AuNPs increase the deposition of calcium content and the expression of marker genes related to osteogenic differentiation in human adipose-derived mesenchymal stem cells at nontoxic concentrations. These results indicate that chitosan-conjugated AuNPs promote osteogenesis through the Wnt/β-catenin signaling pathway. Therefore, chitosan-conjugated AuNPs can be used as a reagent for promoting bone formation. Keywords: chitosan-conjugated gold nanoparticle, mineralization, nonphosphorylated beta-catenin

Candidate genes for COPD: current evidence and research

Directory of Open Access Journals (Sweden)

Kim WJ

2015-10-01

Full Text Available Woo Jin Kim,1 Sang Do Lee2 1Department of Internal Medicine and Environmental Health Center, Kangwon National University, Chuncheon, 2Department of Pulmonary and Critical Care Medicine, Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea Abstract: COPD is a common complex disease characterized by progressive airflow limitation. Several genome-wide association studies (GWASs have discovered genes that are associated with COPD. Recently, candidate genes for COPD identified by GWASs include CHRNA3/5 (cholinergic nicotine receptor alpha 3/5, IREB2 (iron regulatory binding protein 2, HHIP (hedgehog-interacting protein, FAM13A (family with sequence similarity 13, member A, and AGER (advanced glycosylation end product–specific receptor. Their association with COPD susceptibility has been replicated in multiple populations. Since these candidate genes have not been considered in COPD, their pathological roles are still largely unknown. Herein, we review some evidences that they can be effective drug targets or serve as biomarkers for diagnosis or subtyping. However, more study is required to understand the functional roles of these candidate genes. Future research is needed to characterize the effect of genetic variants, validate gene function in humans and model systems, and elucidate the genes’ transcriptional and posttranscriptional regulatory mechanisms. Keywords: chronic obstructive pulmonary disease, genetics, genome-wide association study

Scaled particle theory for a hard spherocylinder fluid in a disordered porous medium: Carnahan-Starling and Parsons-Lee corrections

Directory of Open Access Journals (Sweden)

M.F. Holovko

2018-03-01

Full Text Available The scaled particle theory (SPT approximation is applied for the study of the influence of a porous medium on the isotropic-nematic transition in a hard spherocylinder fluid. Two new approaches are developed in order to improve the description in the case of small lengths of spherocylinders. In one of them, the so-called SPT-CS-PL approach, the Carnahan-Starling (CS correction is introduced to improve the description of thermodynamic properties of the fluid, while the Parsons-Lee (PL correction is introduced to improve the orientational ordering. The second approach, the so-called SPT-PL approach, is connected with generalization of the PL theory to anisotropic fluids in disordered porous media. The phase diagram is obtained from the bifurcation analysis of a nonlinear integral equation for the singlet distribution function and from the thermodynamic equilibrium conditions. The results obtained are compared with computer simulation data. Both ways and both approaches considerably improve the description in the case of spherocylinder fluids with smaller spherocylinder lengths. We did not find any significant differences between the results of the two developed approaches. We found that the bifurcation analysis slightly overestimates and the thermodynamical analysis underestimates the predictions of the computer simulation data. A porous medium shifts the phase diagram to smaller densities of the fluid and does not change the type of the transition.

The health care burden of high grade chronic obstructive pulmonary disease in Korea: analysis of the Korean Health Insurance Review and Assessment Service data

Directory of Open Access Journals (Sweden)

Kim JH

2013-11-01

Full Text Available JinHee Kim,1 Chin Kook Rhee,2 Kwang Ha Yoo,3 Young Sam Kim,4 Sei Won Lee,5 Yong Bum Park,6 Jin Hwa Lee,7 YeonMok Oh,5 Sang Do Lee,5 Yuri Kim,8 KyungJoo Kim,8 HyoungKyu Yoon9 1Office of Health Service Research, National Evidence-Based Healthcare Collaborating Agency, Seoul, Korea; 2Department of Internal Medicine, Seoul St Mary’s Hospital, Catholic University of Korea College of Medicine, Seoul, Korea; 3Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea; 4Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea; 5Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; 6Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Hallym University Kangdong Sacred Heart Hospital, Seoul, Korea; 7Department of Internal Medicine, School of Medicine, Ewha Womans University, Seoul, Korea; 8Department of Clinical Research Support, National Strategic Coordinating Center for Clinical Research, Seoul, Korea; 9Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yeouido St Mary’s Hospital, Catholic University of Korea College of Medicine, Seoul, Korea Background: Patients with high grade chronic pulmonary obstructive disease (COPD account for much of the COPD-related mortality and incur excessive financial burdens and medical care utilization. We aimed to determine the characteristics and medical care use of such patients using nationwide data from the Korean Health Insurance Review and Assessment Service in 2009. Materials and methods: Patients with COPD were identified by searching with the International Classification of Diseases–10th Revision for those using medication. Patients with high grade COPD were selected based on their patterns of tertiary institute visits and medication use. Results: The numbers of patients with high grade COPD increased rapidly

Zinc oxide nanoparticles: a 90-day repeated-dose dermal toxicity study in rats

Directory of Open Access Journals (Sweden)

Ryu HJ

2014-12-01

Full Text Available Hwa Jung Ryu,1,* Mu Yeb Seo,2,* Sung Kyu Jung,1 Eun Ho Maeng,2 Seung-Young Lee,2 Dong-Hyouk Jang,2 Taek-Jin Lee,2 Ki-Yeon Jo,2 Yu-Ri Kim,3 Kyu-Bong Cho,4 Meyoung-Kon Kim,3 Beom Jun Lee,5 Sang Wook Son1 1Department of Dermatology, Korea University College of Medicine, Seoul, 2Korea Testing and Research Institute, Gyunggido, 3Department of Biochemistry and Molecular Biology, Korea University College of Medicine, Seoul, 4Department of Clinical Laboratory Science, Shinheung College, Uijeongbu, 5College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea *These authors contributed equally to this work and both should be considered first authors Abstract: Zinc oxide (ZnO works as a long-lasting, broad-spectrum physical sunblock, and can prevent skin cancer, sunburn, and photoaging. Nanosized ZnO particles are used often in sunscreens due to consumer preference over larger sizes, which appear opaque when dermally applied. Although the US Food and Drug Administration approved the use of nanoparticles (NPs in sunscreens in 1999, there are ongoing safety concerns. The aim of this study was to evaluate the subchronic toxicity of ZnO NPs after dermal application according to the Organization for Economic Cooperation and Development Test Guidelines 411 using Good Laboratory Practice. Sprague Dawley rats were randomly divided into eight (one control, one vehicle control, three experimental, and three recovery groups. Different concentrations of ZnO NPs were dermally applied to the rats in the experimental groups for 90 days. Clinical observations as well as weight and food consumption were measured and recorded daily. Hematology and biochemistry parameters were determined. Gross pathologic and histopathologic examinations were performed on selected tissues from all animals. Analyses of tissue were undertaken to determine target organ tissue distribution. There was no increased mortality in the experimental group. Although there

Prevalence of and risk factors for postoperative pulmonary complications after lung cancer surgery in patients with early-stage COPD

Directory of Open Access Journals (Sweden)

Kim ES

2016-06-01

Full Text Available Eun Sun Kim,1 Young Tae Kim,2 Chang Hyun Kang,2 In Kyu Park,2 Won Bae,1 Sun Mi Choi,1 Jinwoo Lee,1 Young Sik Park,1 Chang-Hoon Lee,1 Sang-Min Lee,1 Jae-Joon Yim,1 Young Whan Kim,1 Sung Koo Han,1 Chul-Gyu Yoo1 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, 2Department of Thoracic and Cardiovascular Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea Purpose: This study aimed to investigate whether the prevalence of postoperative pulmonary complications (PPCs in patients with non-small-cell lung cancer (NSCLC is even higher in the early stages of COPD than in such patients with normal lung function and to verify the usefulness of symptom- or quality of life (QoL-based scores in predicting risk for PPCs.Patients and methods: Patients undergoing pulmonary resection for NSCLC between July 2012 and October 2014 were prospectively enrolled. Preoperative measurements of lung function, dyspnea, and QoL, operative characteristics, PPCs, duration of postoperative hospitalization, and in-hospital mortality were assessed.Results: Among 351 consecutive patients with NSCLC, 343 patients with forced expiratory volume in 1 second (FEV1 ≥70% of predicted value were enrolled. At least one PPC occurred in 57 (16.6% patients. Prevalence of PPC was higher in patients with COPD (30.1% than in those with normal spirometry (10.0%; P<0.001. However, in patients with COPD, the prevalence of PPC was not different in patients with FEV1 ≥70% compared to those with FEV1 <70% and between group A (low risk and less symptoms and group B (low risk and more symptoms patients with COPD, based on the new Global initiative for chronic Obstructive Lung Disease 2011 guidelines. In patients with COPD, body mass index (odds ratio [OR]: 0.80, P=0.007, carbon monoxide diffusing capacity of the lung (DLCO, % predicted value (OR: 0.97, P=0.024, and operation time (OR: 1.01, P=0.003, but not COPD assessment test or St

Remote monitoring of chlorophyll fluorescence in two reef corals during the 2005 bleaching event at Lee Stocking Island, Bahamas

Science.gov (United States)

Manzello, D.; Warner, M.; Stabenau, E.; Hendee, J.; Lesser, M.; Jankulak, M.

2009-03-01

Zooxanthellae fluorescence was measured in situ, remotely, and in near real-time with a pulse amplitude modulated (PAM) fluorometer for a colony of Siderastrea siderea and Agaricia tenuifolia at Lee Stocking Island, Bahamas during the Caribbean-wide 2005 bleaching event. These colonies displayed evidence of photosystem II (PS II) inactivation coincident with thermal stress and seasonally high doses of solar radiation. Hurricane-associated declines in temperature and light appear to have facilitated the recovery of maximum quantum yield of PS II within these two colonies, although both corals responded differently to individual storms. PAM fluorometry, coupled with long-term measurement of in situ light and temperature, provides much more detail of coral photobiology on a seasonal time scale and during possible bleaching conditions than sporadic, subjective, and qualitative observations. S. siderea displayed evidence of PS II inactivation over a month prior to the issuing of a satellite-based, sea surface temperature (SST) bleaching alert by the National Oceanic and Atmospheric Administration (NOAA). In fact, recovery had already begun in S. siderea when the bleaching alert was issued. Fluorescence data for A. tenuifolia were difficult to interpret because the shaded parts of a colony were monitored and thus did not perfectly coincide with thermal stress and seasonally high doses of solar radiation as in S. siderea. These results further emphasize the limitations of solely monitoring SST (satellite or in situ) as a bleaching indicator without considering the physiological status of coral-zooxanthellae symbioses.

The contributions of Donald Lee Johnson to understanding the Quaternary geologic and biogeographic history of the California Channel Islands

Science.gov (United States)

Muhs, Daniel R.

2013-01-01

Over a span of 50 years, native Californian Donald Lee Johnson made a number of memorable contributions to our understanding of the California Channel Islands. Among these are (1) recognizing that carbonate dunes, often cemented into eolianite and derived from offshore shelf sediments during lowered sea level, are markers of glacial periods on the Channel Islands; (2) identifying beach rock on the Channel Islands as the northernmost occurrence of this feature on the Pacific Coast of North America; (3) recognizing of the role of human activities in historic landscape modification; (4) identifying both the biogenic and pedogenic origins of caliche “ghost forests” and laminar calcrete forms on the Channel Islands; (5) providing the first soil maps of several of the islands, showing diverse pathways of pedogenesis; (6) pointing out the importance of fire in Quaternary landscape history on the Channel Islands, based on detailed stratigraphic studies; and (7), perhaps his greatest contribution, clarifying the origin of Pleistocene pygmy mammoths on the Channel Islands, due not to imagined ancient land bridges, but rather the superb swimming abilities of proboscideans combined with lowered sea level, favorable paleowinds, and an attractive paleovegetation on the Channel Islands. Don was a classic natural historian in the great tradition of Charles Darwin and George Gaylord Simpson, his role models. Don’s work will remain important and useful for many years and is an inspiration to those researching the California Channel Islands today.

Effect of an Arctium lappa (burdock extract on the labeling of blood constituents with technetium-99m and on the morphology of the red blood cells

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Rosane de Figueiredo Neves

2007-09-01

Full Text Available Arctium lappa (burdock has been used to treat inflammatory processes. Blood constituents labeled with technetium-99m (99mTc have been utilized in nuclear medicine. It was evaluated the influence of a burdock extract on the labeling of blood constituents with 99mTc and on the morphometry of red blood cells. Blood samples from Wistar rats were incubated with burdock extract and the radiolabeling procedure was carried out. Plasma and blood cells, soluble and insoluble fractions of plasma and blood cells were separated. The radioactivity in each fraction was counted and the percentages of radioactivity (%ATI were determined. Morphology and morphometric (perimeter/area ratio measurements of red blood cells (RBC were performed. The incubation with burdock extract significantly (pArctium lappa (bardana tem sido utilizada na medicina popular para o tratamento de processos inflamatórios. Constituintes sangüíneos marcados com tecnécio-99m (99mTc são utilizados na medicina nuclear para obtenção de imagens. Neste trabalho foi avaliada a influência de um extrato de bardana na marcação de constituintes sangüíneos com 99mTc e na morfologia de hemácias. Amostras de sangue de ratos Wistar foram incubadas com extrato de bardana e o processo de radiomarcação de constituintes sangüíneos foi realizado. Plasma e células sangüíneas, frações solúvel e insolúvel do plasma e das células sangüíneas foram separadas, a radioatividade em cada fração foi contada e as porcentagens de radioatividade (%ATI foram determinadas. A morfologia e a relação perímetro/área das hemácias foram avaliadas. A incubação de sangue com o extrato de bardana alterou significativamente (p<0.05 a %ATI a distribuição de radioatividade nos compartimentos plasmático e celular. A relação perímetro/área de hemácias, bem como a forma das hemácias também sofreram alterações Modificações na membrana poderiam justificar a diminuição da marcação das c

Flux of nitrogen, phosphorus, and suspended sediment from the Susquehanna River Basin to the Chesapeake Bay during Tropical Storm Lee, September 2011, as an indicator of the effects of reservoir sedimentation on water quality

Science.gov (United States)

Hirsch, Robert M.

2012-01-01

Concentrations of nitrogen, phosphorus, and suspended sediment are measured at the U.S. Geological Survey streamgage at Conowingo Dam at the downstream end of the Susquehanna River Basin in Maryland, where the river flows into the Chesapeake Bay. During the period September 7-15, 2011, in the aftermath of Tropical Storm Lee, concentrations of these three constituents were among the highest ever measured at this site. These measurements indicate that sediment-storage processes behind the three dams on the lower Susquehanna River are evolving. In particular, they indicate that scouring of sediment (and the nitrogen and phosphorus attached to that sediment) may be increasing with time. Trends in flow-normalized fluxes at the Susquehanna River at Conowingo, Maryland, streamgage during 1996-2011 indicate a 3.2-percent decrease in total nitrogen, but a 55-percent increase in total phosphorus and a 97-percent increase in suspended sediment. These large increases in the flux of phosphorus and sediment from the Susquehanna River to the Chesapeake Bay have occurred despite reductions in the fluxes of these constituents from the Susquehanna River watershed upstream from the reservoirs. Although the Tropical Storm Lee flood event contributed about 1.8 percent of the total streamflow from the Susquehanna River to the Chesapeake Bay over the past decade (water years 2002-11), it contributed about 5 percent of the nitrogen, 22 percent of the phosphorus, and 39 percent of the suspended sediment during the same period. These results highlight the importance of brief high-flow events in releasing nitrogen, phosphorus, and sediment derived from the Susquehanna River watershed and stored in the Conowingo Reservoir to the Chesapeake Bay.

Pharmacological study of radioactive-gold colloid transport by blood and by serous exudate; Contribution a l'etude pharmacologique du transport des colloides d'or radioactif par le sang et les exsudats sereux

Energy Technology Data Exchange (ETDEWEB)

Rousselet, J. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1966-06-01

After giving the essential physico-chemical properties of the colloids, the author considers the biological role of these substances and, in connection with their transport by the blood, their capture by elements of the reticula-endothelial system. A summary is given of present knowledge concerning the role of serous proteins in the transport of substances, particularly that of radio-active colloidal gold. The blood fractions which can take part in colloidal gold transport are the red blood corpuscles, the leukocytes and histiocytic elements as well as the plasma. The radioactive distribution in these various fractions is obtained by autoradiography of blood sediments. After showing the importance of the role of the plasma in radioactive particle transport, the author, describes the attempts made to detect a possible of colloidal gold 198 on the various serous proteins using various methods of separation. The ''in vitro'' and ''in vivo'' bonds between colloidal gold-198 particles and either the serous proteins or healthy specimens or the effusion liquids of pathological origin in man, or due to an experimental inflammation with carregenin in the rat, have been studied. The bonding appears to be effective because of the protective macromolecular layer formed by the gelatine. The different positions of the colloidal grains on the electrophoregram can only be explained by their different physico-chemical characteristics. Gold in the ionic form, on the other hand, is combined only with the albumen is the amount metal present does not exceed a certain value. (author) [French] Apres avoir enonce les proprietes physicochimiques essentielles des colloides nous etudions le devenir biologique de ces substances et, en relation avec leur transport par le sang, leur captation par les elements du Systeme Reticulo-Endothelial. Nous resumons les connaissances acquises jusqu'alors sur le role des proteines seriques dans le transport des

Til kroppen og hovedet

DEFF Research Database (Denmark)

Bonde, Anders

2012-01-01

Anmeldelse af koncertarrangementet "A Song for Bayes" på Skråen, Aalborg, d. 27. februar 2012 - et musikalsk eksperiment, der undersøger, om man kan lave musik ud fra Bayesianske net, og hvordan (http://bayesmusic.wordpress.com/hvad-er-en-sang-for-bayes/).......Anmeldelse af koncertarrangementet "A Song for Bayes" på Skråen, Aalborg, d. 27. februar 2012 - et musikalsk eksperiment, der undersøger, om man kan lave musik ud fra Bayesianske net, og hvordan (http://bayesmusic.wordpress.com/hvad-er-en-sang-for-bayes/)....

Når troen bliver til sang

DEFF Research Database (Denmark)

Nielsen, Kirsten

2009-01-01

I anmeldelsen fremhæver jeg, at Selander i denne artikelsamling både beskæftiger sig med salmeteksterne og med melodierne. Denne dobbeltkompetence er usædvanlig hos en litteraturforsker. Artiklerne giver et fint indblik i svensk salmetradition samt i komponisternes arbejde med melodierne. Selande...

Indigenizing CBPR: evaluation of a community-based and participatory research process implementation of the Elluam Tungiinun (towards wellness) program in Alaska.

Science.gov (United States)

Rasmus, Stacy M

2014-09-01

The process that community based participatory research (CBPR) implementation takes in indigenous community contexts has serious implications for health intervention outcomes and sustainability. An evaluation of the Elluam Tungiinun (Towards Wellness) Project aimed to explore the experience of a Yup'ik Alaska Native community engaged within a CBPR process and describe the effects of CBPR process implementation from an indigenous community member perspective. CBPR is acknowledged as an effective strategy for engaging American Indian and Alaska Native communities in research process, but we still know very little about the experience from a local, community member perspective. What are the perceived outcomes of participation in CBPR from a local, community member perspective? Qualitative methods were used to elicit community member perspectives of participation in a CBPR process engaged with one Yup'ik community in southwest Alaska. Results focus on community member perceptions of CBPR implementation, involvement in the process and partnership, ownership of the project with outcomes observed and perceived at the community, family and individual levels, and challenges. A discussion of findings demonstrates how ownership of the intervention arose from a translational and indigenizing process initiated by the community that was supported and enhanced through the implementation of CBPR. Community member perspectives of their participation in the research reveal important process points that stand to contribute meaningfully to implementation science for interventions developed by and for indigenous and other minority and culturally diverse peoples.

Effect of an extract of Artemisia vulgaris L. (Mugwort on the in vitro labeling of red blood cells and plasma proteins with technetium-99m

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Danielle Amorim Terra

2007-09-01

Full Text Available The aim of this work was to evaluate the effect of an extract of the Artemisia vulgaris L. (mugwort on the labeling of blood constituents with technetium-99m (99mTc. Blood samples from Wistar rats were incubated with a mugwort extract and the radiolabeling of blood constituents was carried out. Plasma and blood cells were separated by centrifugation. Aliquots of plasma and blood cells were also precipitated with trichloroacetic acid and centrifuged to isolate soluble and insoluble fractions of plasma and blood cells. Radioactivity in each fraction was counted and the percentages of radioactivity (%ATI was calculated. Mugwort extract decreased significantly (pO objetivo desse trabalho foi avaliar o efeito da Artemisia vulgaris L.(artemisa na marcação dos constituintes sangüíneos com tecnécio-99m (99mTc. Amostras de sangue obtidas de ratos Wistar foram incubadas com um extrato de artemisa e o processo de radiomarcação dos constituintes sangüíneos foi realizado. Plasma e células sangüíneas foram isoladas por centrifugação. Alíquotas de plasma e células sangüíneas foram também precipitadas com ácido tricloroacético para isolamento de frações solúvel e insolúvel. A radiatividade em cada fração foi contada e as porcentagens de radioatividade (%ATI foram calculadas. O extrato de artemisa diminuiu significantemente (p<0,05 a %ATI nas células sanguíneas e nas proteínas celulares. A análise dos resultados indicou que o extrato de artemisa apresentaria substâncias que interferir no transporte de íons estanoso e/ou pertecnetato através da membrana do eritrócito alterando a marcação das células sangúineas com 99mTc.

Time-lapse analysis of methane quantity in Mary Lee group of coal seams using filter-based multiple-point geostatistical simulation

Science.gov (United States)

Karacan, C. Özgen; Olea, Ricardo A.

2013-01-01

Coal seam degasification and its success are important for controlling methane, and thus for the health and safety of coal miners. During the course of degasification, properties of coal seams change. Thus, the changes in coal reservoir conditions and in-place gas content as well as methane emission potential into mines should be evaluated by examining time-dependent changes and the presence of major heterogeneities and geological discontinuities in the field. In this work, time-lapsed reservoir and fluid storage properties of the New Castle coal seam, Mary Lee/Blue Creek seam, and Jagger seam of Black Warrior Basin, Alabama, were determined from gas and water production history matching and production forecasting of vertical degasification wellbores. These properties were combined with isotherm and other important data to compute gas-in-place (GIP) and its change with time at borehole locations. Time-lapsed training images (TIs) of GIP and GIP difference corresponding to each coal and date were generated by using these point-wise data and Voronoi decomposition on the TI grid, which included faults as discontinuities for expansion of Voronoi regions. Filter-based multiple-point geostatistical simulations, which were preferred in this study due to anisotropies and discontinuities in the area, were used to predict time-lapsed GIP distributions within the study area. Performed simulations were used for mapping spatial time-lapsed methane quantities as well as their uncertainties within the study area.

Efeitos das cardioplegias sangüíneas hipotérmica e normotérmica nos substratos intracelulares em pacientes com corações hipertróficos The effect of cold and warm blood cardioplegia on intracellular substrates in patients with hypertrophic hearts

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Walter J. GOMES

2000-06-01

Full Text Available OBJETIVOS: As cardioplegias sangüíneas normotérmica e hipotérmica, administradas de maneira anterógrada e intermitente, têm demonstrado serem eficientes na proteção miocárdica em cirurgias de revascularização miocárdica. Entretanto, pouco se conhece da eficiência dessas técnicas em corações hipertróficos. Dessa maneira, foram estudados seus efeitos nos substratos intracelulares miocárdicos em pacientes portadores de estenose aórtica, submetidos a cirurgia de troca valvar aórtica. CASUÍSTICA E MÉTODOS: A concentração intracelular miocárdica dos substratos (ATP, lactato, glutamato, aspartato e alanina foi medida em biópsias de ventrículo esquerdo de 20 pacientes submetidos a troca valvar aórtica, usando, como método de proteção miocárdica, cardioplegia sangüínea normotérmica (n=10 ou hipotérmica (n=10, administradas de forma anterógrada e intermitente. As biópsias foram retiradas 5 minutos após o início da circulação extracorpórea (controle, 30 minutos após o pinçamento aórtico (isquemia e 20 minutos após o despinçamento (reperfusão. RESULTADOS: Não houve alterações significantes na concentração intracelular dos substratos nas amostras coletadas durante o período isquêmico, em comparação ao controle. Na reperfusão, entretanto, houve significante queda nos valores de ATP e aminoácidos em ambos os grupos, em relação ao grupo controle. CONCLUSÃO: Os dados sugerem que ambos os protocolos de proteção miocárdica empregados não foram eficientes na proteção miocárdica de corações hipertróficos.OBJECTIVE: Warm intermittent blood cardioplegia has been shown to prevent the reperfusion damage seen when cold blood cardioplegia is used in patients undergoing coronary revascularization. Little is known on the effects of these two cardioplegic techniques on hypertrophic hearts. The aim of this study was to investigate the comparative effects of cold and warm antegrade blood cardioplegia in

Eesti luuletaja päris oma prantsuse luuleraamat. August Sanga, Jaan Krossi ja Ain Kaalepi loomingust 1960. aastail / An Estonian Poet’s Own Book of French Poetry. About the Works of August Sang, Jaan Kross and Ain Kaalep in the 1960s

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Katre Talviste

2013-12-01

Full Text Available This article positions the translations of French verse works (plays and selected collections of individual poets that August Sang, Jaan Kross and Ain Kaalep made in the 1960s, onto the background of their own original works. At that time, August Sang translated four plays by Molière (The Misanthrope, Tartuffe, The School for Wives in 1961; Amphitryon in 1961, which have already been discussed in relation to the tradition of translating the French syllabic verse into Estonian, because these translations form a considerable part of the body of Estonian translations of French verse poetry. For Jaan Kross and Ain Kaalep, the wider context is created by the so-called free verse battles in the 1950s, to which we can link Kross’ translation of a selected collection of Éluard (Veel enne kostma peab, 1969 and Kaalep’s translation of a selected collection of Prévert (Kuidas portreteerida lindu, 1965. One of the two remaining translations by Kross, (Rostand’s Cyrano de Bergerac, 1964, can also be examined in relation to the problems of translating verse, but the other, (Béranger’s Laulud, 1963, should be discussed in the framework of intellectual and cultural resistance, a part of which was also the struggle put up for the existence of free verse in the 1950s and 1960s. Of August Sang’s original work, the article examines his collection of poems Võileib suudlusega (1963, written simultaneously with his translations of Molière’s plays and published right after them. Both the translations and the collection of original poems have attracted critics’ attention with their remarkable lack of linguistic constraint and simplicity. Although Sang has rarely voiced theoretical ideas about translation or explained his method, both his poetic image, outlined in the collection Võileib suudlusega, and his search for right words, reflected in the drafts of his translations, let us believe that the simplicity of expression and the avoidance of marked

Saline-water intrusion related to well construction in Lee County, Florida

Science.gov (United States)

Boggess, Durward Hoye; Missimer, T.M.; O'Donnell, T. H.

1977-01-01

Ground water is the principle source of water supply in Lee County, Florida where an estimated 30,000 wells have been drilled since 1990. These wells ranges in depth from about 10 to 1,240 feet and tap the water table aquifer or one or more of the artesian water-bearing units or zones in the Tamiami Formation, the upper part of the Hawthorn Formation, the lower part of the Hawthorn Formation and the Tampa Limestone and the Suwannee Limestone. Before 1968, nearly all wells were constructed with galvanized or black iron pipe. Many of these wells are sources of saline-water intrusion into freshwater-bearing zones. The water-bearing zones in the lower part of the Hawthorn Formation, Tampa Limestone, and Suwannee Limestone are artesian-they have higher water levels and usually contain water with a higher concentration of dissolved solids than do the aquifers occurring at shallower depths. The water from these deeper aquifers generally range in dissolved solids concentration from about 1,500 to 2,400 mg/L, and in chloride from about 500 to 1,00 mg/L. A maximum chloride concentration of 15,200 mg/L has been determined. Few of the 3,00 wells estimated to have been drilled to these zones contain sufficient casing to prevent upward flow into overlaying water-bearing zones. Because of water-level differentials, upward movement and lateral intrusion of saline water occurs principally into the upper part of the Hawthorn Formation where the chloride concentrations in water unaffected by saline-water intrusion ranges from about 80 to 150 mg/L. Where intrusion from deep artesian zones has occurred, the chloride concentration in water from the upper part of the Hawthorn Formation ranges from about 300 to more than 2,100 mg/L Surface discharges of the saline water from wells tapping the lower part of the Hawthorn Formation and the Suwannee Limestone also had affected the water-table aquifer which normally contains water with 10 to 50 mg/L of chloride. In one area, the chloride

Association between vitamin D receptor polymorphisms and osteoporosis in patients with COPD

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Kim SW

2015-09-01

Full Text Available Sei Won Kim,1 Jong Min Lee,1 Jick Hwan Ha,1 Hyeon Hui Kang,1 Chin Kook Rhee,1 Jin Woo Kim,1 Hwa Sik Moon,1 Ki Hyun Baek,2 Sang Haak Lee1 1Division of Pulmonology, Critical Care and Sleep Medicine, 2Division of Endocrinology and Metabolism, Department of Internal Medicine, St Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Background: Patients with COPD are at an increased risk of osteoporosis. Although many studies have addressed the relationship between the vitamin D receptor (VDR polymorphisms and bone health, this relationship has not been fully investigated in patients with COPD. In this study, we investigated the association of VDR polymorphisms with bone mineral density (BMD and other clinical parameters in patients with COPD. Patients and methods: In total, 200 patients with COPD were included in this study. The VDR polymorphisms rs1544410 (A/G-BsmI, rs7975232 (A/C-ApaI, rs731236 (C/T-TaqI, and rs10735810 (C/T-FokI were determined by Sanger sequencing using blood DNA samples. BMD of the lumbar vertebra and the femoral neck was measured by dual-energy X-ray absorptiometry. Other clinical parameters were also evaluated. Haplotype and multivariate analyses were also performed. Results: Sex, body mass index, steroid use, percentage of forced expiratory volume in 1 second (FEV1, alkaline phosphatase, and 25-hydroxyvitamin D significantly influenced the risk of osteoporosis. Patients with osteoporosis were more likely to carry the rs7975232 C allele compared to normal patients with BMD. Haplotypes GCT and GAT were related to osteoporosis. Patients without the haplotype GAT allele showed a significantly lower T-score at the femoral neck and an increased risk of osteoporosis (odds ratio [OR]= 2.78, 95% confidence interval [CI]= 1.20–6.48, P=0.018 compared with carriers in the dominant model. Conclusion: Genetic variations in VDR are significantly associated with osteoporosis among patients with COPD

Preclinical pharmacokinetics, interspecies scaling, and pharmacokinetics of a Phase I clinical trial of TTAC-0001, a fully human monoclonal antibody against vascular endothelial growth factor 2

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Lee WS

2018-03-01

Full Text Available Weon Sup Lee,1 Sang Ryeol Shim,1 Seon Young Lee,1 Jin San Yoo,1 Sung Kweon Cho2 1PharmAbcine, Inc., Daejeon, Republic of Korea; 2Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea Background: VEGF is a highly selective mitogen that serves as the central regulator of tumor angiogenesis by mediating endothelial proliferation, permeability, and survival. Tanibirumab (TTAC-0001 is a fully human IgG1 monoclonal antibody derived from a fully human naïve single-chain variable fragment (ScFv phage library that was developed to inhibit the effects of VEGF in the treatment of solid tumors, especially those of the brain. Methods: In the present study, we conducted intravenous pharmacokinetic studies of TTAC-0001 in mice, rats, and cynomolgus monkeys. At the doses studied (3 mg/kg, 10 mg/kg, 30 mg/kg, TTAC-0001 exhibited dose proportionality in mice and monkeys. At a dose of ~10 mg/kg, the clearance of TTAC-0001 from serum was 0.017 mL/h in mice, 0.35 mL/h in rats, and 2.19 mL/h in cynomolgus monkeys, and the terminal half-life ranged from 20–30 h among the three species. Pharmacokinetic data in mice, rats, and cynomolgus monkeys were used to predict the pharmacokinetics of TTAC-0001 in humans using allometric scaling. The predicted serum clearance of TTAC-0001 in humans was 102.45 mL/h and the terminal half-life was 27.52 h. Results: The maximum life span-corrected clearance value was 72.92 mL/h. The observed clearance in humans was more similar to the predicted scaled clearance. Conclusion: We investigated the pharmacokinetics of TTAC-0001 in mice, rats, and cynomolgus monkeys after intravenous administration. At the doses studied, TTAC-0001 exhibited dose proportionality in mice and monkeys. The scaled pharmacokinetics of TTAC-0001 reported here was useful for designing first-in-human studies. Allometric scaling in the therapeutic antibody is feasible. Keywords: VEGF2, tanibirumab, pharmacokinetics

The effectiveness of Lee Silverman Voice Treatment therapy issued interactively through an iPad device: A non-inferiority study.

Science.gov (United States)

Griffin, Murray; Bentley, John; Shanks, Joseph; Wood, Carly

2018-04-01

Introduction This study compared the differences in recorded speech variables between people treated with conventional 'in person' Lee Silverman Voice Treatment (LSVT) and those treated remotely via iPad-based 'Facetime'. Method Eight participants were selected for the iPad LSVT, and 21 similarly matched subjects were selected from existing data to form the 'in person' group. Participants in both groups had diagnosed idiopathic Parkinson's disease and moderate hypokinetic dysarthria. Eighteen sessions of prescribed LSVT comprising a pre-treatment assessment, 16 treatment sessions, and a six months' post-treatment assessment were administered for each person. In both groups, pre- and post-treatment assessments were conducted face-to-face. Performance measures were recorded during assessment and treatment. Average measures were determined for all tasks at all time points and a summary outcome variable was composed from across-task performance. Results Non-inferiority testing confirmed that iPad LSVT was non-inferior in treating all LSVT task 3 variables except generating words, with the 90% upper confidence intervals (CI) lying between the non-inferiority margin of ± 2.25 and zero. The iPad was superior in treating the task 3 rainbow reading passage and describing motor task variables with upper and lower 90% CI values being negative. The improvement in the summary outcome variable score was also superior in the iPad group. Discussion Non-inferiority testing implies that the iPad LSVT is non-inferior in treating task three variables when compared to traditional LSVT. The study supports further development of remote delivery solutions involving the Apple iPad and 'Facetime' system as a means of improving access to services and the participant's experience.

Co-authorship patterns and networks of Korean radiation oncologists

International Nuclear Information System (INIS)

Choi, Jin Hyun; Kang, Jin Oh; Park, Seo Hyun; Kim, Sang Ki

2011-01-01

and Oncology and others (p = 0.000), respectively. Among the analysis, a significant difference in the average number of author per article was indicated. The out-degree centrality of network among authors was 4.26% (2.03-7.09%) while in-degree centrality was 1.31% (0.53-2.84%). The three significant nodes were classified and listed as following: Choi, Eun Kyung for 1991-1995, Kim, Dae Young for 1998-2001, Park, Won and Lee, Sang Wook for 2003-2010. Choi, Eun Kyung and Kim, Dae Young appeared in two cases, and ranked as the highest degree in centrality. In the key player analysis, Choi, Eun Kyung and Lee, Sang Wook appeared in two cases, and ranked as the highest. From the cluster analysis, Sungkyunkwan University, Seoul National University and Yonsei University revealed as the three large clusters when Ulsan University, Chonnam National University, and Korea Institute of Radiological and Medical Science as the medium clusters. The Korean radiation oncologist's society shows a closed network with numerous relationships among the particular clusters, and the result indicates it is different from other institutions in the pattern of co-authorship formation of the major hospitals.

Transfusão sangüínea no intra-operatório, complicações e prognóstico Transfusión sanguínea en el intraoperatorio, complicaciones y pronóstico Complications and prognosis of intraoperative blood transfusion

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João Manoel Silva Junior

2008-10-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: Transfusões sangüíneas no intra-operatório estão associadas a aumento de complicações no pós-operatório e custos hospitalares. Portanto, este estudo avaliou as características, complicações e possíveis fatores de riscos para morte em pacientes cirúrgicos que necessitaram de transfusões sangüíneas no intra-operatório. MÉTODO: Coorte prospectiva, durante período de um ano, no centro cirúrgico de hospital terciário. Incluíram-se pacientes com idade acima de 18 anos que necessitaram de transfusões sangüíneas no intra-operatório. Testemunhas de Jeová, pacientes que receberam transfusões prévias, falência coronariana e lesão encefálica aguda foram excluídos. RESULTADOS: O estudo envolveu 80 pacientes, com idade média de 68,4 ± 14,1 anos. Os pacientes ASA II foram prevalentes com 69,6% dos casos, os escores APACHE II e POSSUM foram em média, respectivamente, 13,6 ± 4,4 e 37,5 ± 11,4. A hemoglobina média no momento da transfusão era 8,2 ± 1,8 g.dL-1 e 19% dos pacientes apresentavam hemoglobina maior que 10 g.dL-1. Os pacientes receberam em média 2,2 ± 0,9 UI de concentrados de hemácias. A mortalidade hospitalar foi 26,3%. As complicações pós-transfusões totalizaram 57,5% dos casos no pós-operatório e a mais freqüente foi infecção. Foram fatores independentes de morte na regressão logística os escores APACHE II (OR = 1,34; IC 95% 1,102 - 1,622, POSSUM (OR = 1,08; IC 95% 1,008 - 1,150 e número de unidades de concentrados de hemácias recebidas (OR = 2,22; IC 95% 1,100 - 4,463. Quanto maior o número de transfusões sangüíneas, maiores as incidências de complicações e mortalidade. CONCLUSÕES: O valor de hemoglobina e o número de unidades de concentrados de hemácias utilizados foram elevados comparados com os estudos que preconizam estratégias restritivas. Foi encontrada nesta amostra alta incidência de complicações, principalmente infecções, e elevada

Numerical experiments on plasma focus for soft x-ray yield scaling laws derivation using Lee model

International Nuclear Information System (INIS)

Akel, M.

2012-09-01

The required plasma parameters of krypton and xenon at different temperatures were calculated, the x-ray emission properties of plasmas were studied, and based on the corona model the suitable temperature range for generating H-like and He-like ions (therefore soft x-ray emissions) of different gases plasma were found. The code is applied to characterize the plasma focus in different plasma focus devices, and for optimizing the nitrogen, oxygen, neon, argon, krypton and xenon soft x-ray yields based on bank, tubes and operating parameters. It is found that the soft x-ray yield increases with changing pressure until it reaches the maximum value for each plasma focus device. Keeping the bank parameters, operational voltage unchanged but systematically changing other parameters, numerical experiments were performed finding the optimum combination of P o , Z o and 'a' for the maximum soft x-ray yield. Thus we expect to increase the soft x-ray yield of plasma focus device several-fold from its present typical operation; without changing the capacitor bank, merely by changing the electrode configuration and the operating pressure. The Lee model code was also used to run numerical experiments on plasma focus devices for optimizing soft x-ray yield with reducing L o , varying L o and 'a' to get engineering designs with maximum soft x-ray yield for these devices at different experimental conditions and gases. Numerical experiments showed the influence of the gas used in plasma focus and its properties on soft x-ray emission and its properties and then on its applications. Scaling laws for soft x-ray of nitrogen, oxygen, neon, argon, krypton and xenon plasma focus, in terms of energy, peak discharge current and focus pinch current were found. Radiative cooling effects are studied indicating that radiative collapse may be observed for heavy noble gases (Ar, Kr, Xe) for pinch currents even below 100 kA. The results show that the line radiation emission and tube voltages have

Numerical experiments on plasma focus for soft x-ray yield scaling laws derivation using Lee model

International Nuclear Information System (INIS)

Akel, M.

2015-01-01

The required plasma parameters of krypton and xenon at different temperatures were calculated, the x-ray emission properties of plasmas were studied, and based on the corona model the suitable temperature range for generating H-like and He-like ions (therefore soft x-ray emissions) of different gases plasma were found. The code is applied to characterize the plasma focus in different plasma focus devices, and for optimizing the nitrogen, oxygen, neon, argon, krypton and xenon soft x-ray yields based on bank, tubes and operating parameters. It is found that t he soft x-ray yield increases with changing pressure until it reaches the maximum value for each plasma focus device. Keeping the bank parameters, operational voltage unchanged but systematically changing other parameters, numerical experiments were performed finding the optimum combination of Po, z0 and 'a' for the maximum soft x-ray yield. Thus we expect to increase the soft x-ray yield of plasma focus device several-fold from its present typical operation; without changing the capacitor bank, merely by changing the electrode configuration and the operating pressure. The Lee model code was also used to run numerical experiments on plasma focus devices for optimizing soft x-ray yield with reducing Lo, varying z0 and 'a' to get engineering designs with maximum soft x-ray yield for these devices at different experimental conditions and gases. Numerical experiments showed the influence of the gas used in plasma focus and its propor ties on soft x-ray emission and its propor ties and then on its applications. Scaling laws for soft x-ray of nitrogen, oxygen, neon, argon, krypton and xenon plasma focus in terms of energy, peak discharge current and focus pinch current were found. Radiative cooling effects are studied indicating that radiative collapse may be observed for heavy noble gases (Ar, Kr, Xe) for pinch currents even below 100 k A. The results show that the line radiation emission and

Guérir de la folie. La dispute sur la transfusion sanguine (1667-1668)

OpenAIRE

Andrault , Raphaële

2014-01-01

International audience; La transfusion sanguine guérirait de la folie.  Ainsi, en 1668, "la transfusion du sang d'un veau avait tellement tempéré les fougues et les bouillons du sang d'un fou, qui depuis quatre mois courait jour et nuit tout nu dans les rues de Paris", qu'il en avait retrouvé la raison (J.-B. Denis). La réalité et les implications d'un tel succès thérapeutique se trouvent au cœur de violents échanges polémiques opposant transfuseurs et anti-transfuseurs pendant plus de deux a...

Diurnal variability of inner-shelf circulation in the lee of a cape under upwelling conditions

Science.gov (United States)

Lamas, L.; Peliz, A.; Dias, J.; Oliveira, P. B.; Angélico, M. M.; Castro, J. J.; Fernandes, J. N.; Trindade, A.; Cruz, T.

2017-07-01

The nearshore circulation in the lee of a cape under upwelling conditions was studied using in-situ data from 3 consecutive summers (2006-2008). Focus was given to a period between 20 July and 04 August 2006 to study the diurnal variability of the cross-shelf circulation. This period was chosen because it had a steady upwelling-favourable wind condition modulated by a diurnal cycle much similar to sea breeze. The daily variability of the observed cross-shelf circulation consisted of three distinct periods: a morning period with a 3-layer vertical structure with onshore velocities at mid-depth, a mid-day period where the flow is reversed and has a 2-layer structure with onshore velocities at the surface and offshore flow below, and, lastly, in the evening, a 2-layer period with intensified offshore velocities at the surface and onshore flow at the bottom. The observed cross-shelf circulation showed a peculiar vertical shape and diurnal variability different from several other systems described in literature. We hypothesize that the flow reversal of the cross-shelf circulation results as a response to the rapid change of the wind magnitude and direction at mid-day with the presence of the cape north of the mooring site influencing this response. A numerical modelling experiment exclusively forced by winds simulated successfully most of the circulation at the ADCP site, especially the mid-day reversal and the evening's upwelling-type structure. This supports the hypothesis that the cross-shelf circulation at diurnal timescales is mostly wind-driven. By analysing the 3D circulation in the vicinity of Cape Sines we came to the conclusion that the diurnal variability of the wind and the flow interaction with topography are responsible for the circulation variability at the ADCP site, though only a small region in the south of the cape showed a similar diurnal variability. The fact that the wind diurnally undergoes relaxation and intensification strongly affects the

Comparison of the fixed ratio and the Z-score of FEV1/FVC in the elderly population: a long-term mortality analysis from the Third National Health and Nutritional Examination Survey

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Oh DK

2018-03-01

Full Text Available Dong Kyu Oh,1 Seunghee Baek,2 Sei Won Lee,1 Jae Seung Lee,1 Sang-Do Lee,1 Yeon-Mok Oh1 1Department of Pulmonary and Critical Care Medicine, Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; 2Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea Background and objective: Despite the ongoing intense debate on the definition of airflow limitation by spirometry in the elderly population, there have only been few studies comparing the fixed ratio and the Z-score of forced expiratory volume in 1 second (FEV1/forced vital capacity (FVC in terms of long-term mortalities. In this study, we aimed to identify the proper method for accurately defining the airflow limitation in terms of long-term mortality prediction in the elderly population. Methods: Data were collected from the Third National Health and Nutrition Examination Survey in the US. Non-Hispanic Caucasians aged 65–80 years were included. The receiver operating characteristic (ROC curves of both methods were plotted and compared for 10-year all-cause, respiratory, and COPD mortalities. Results: Of 1,331 subjects, the mean age was 71.7 years and 805 (60.5% were males. For the 10-year all-cause mortality, the area under the curve (AUC of the fixed ratio was significantly greater than that of the Z-score of FEV1/FVC, but both showed poor prediction performance (0.633 vs 0.616, p<0.001. For the 10-year respiratory and COPD mortalities, both the fixed ratio and the Z-score of FEV1/FVC showed comparable prediction performance with greater AUCs (0.784 vs 0.778, p=0.160, and 0.896 vs 0.896, p=0.971, respectively. Interestingly, the conventional cutoff of 0.7 in the fixed ratio was consistently higher than the optimal for the 10-year all-cause, respiratory, and COPD mortalities (0.70 vs 0.69, 0.62, and 0.61, respectively

Avaliação do efeito de sopas desidratadas ricas em fibras na redução do colesteroal sangüíneo em ratos Evaluation of the cholesterol-lowering efect of high-fiber dehydrated soup in rats

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Hercia Stampini Duarte

1998-12-01

Full Text Available Neste estudo foi avaliado o efeito de quatro formulações dietéticas ricas em fibra solúvel na redução de colesterol sangüíneo em ratos. As formulações foram preparadas com farinha de soja desengordurada, farelo de aveia, cebola desidratada, fibra de soja, condimentos e aromas. Duas das formulações continham feijão preto FP(+ e FP(-, nos níveis de 40 e 30%, respectivamente. As outras duas continham feijão vermelho FV(+ e FV(-, nesses mesmos teores. Foram utilizados seis grupos de oito ratos machos, com peso médio inicial de 200g. O grupo Padrão recebeu dieta basal. O grupo Controle recebeu dieta de composição semelhante à Padrão, porém, acrescida de 1% de colesterol cristalino e 0,1% de ácido cólico. As demais dietas foram semelhantes ao grupo Controle, substituídas pelas formulações FV(+, FP(+, FV(- e FP(-, de modo a fornecerem 7,4% de fibra total da dieta. Ratos alimentados com dieta do grupo Controle apresentaram aumento significativo dos níveis de colesterol sérico, peso dos fígados, colesterol e lipídio total das fezes e dos fígados, em relação ao grupo recebendo dieta Padrão. As dietas FV(+, FP(+, FV(- e FP(-, não diferiram entre si quanto ao efeito nos níveis de lipídios séricos e glicose, no peso e lipídio total dos fígados e no peso, umidade e nitrogênio das fezes. No entanto, reduziram significativamente os níveis sangüíneos de colesterol total em 29,0%, os níveis de HDL - colesterol em 34,0%, o peso dos fígados em 11,7% e o colesterol do fígado em 9,0% em relação à dieta Controle. As dietas de feijão vermelho proporcionaram maior redução de colesterol no fígado e maior excreção de lipídio e colesterol nas fezes comparadas com as de feijão preto.The effect of 4 high fiber dietary formulas on reducing blood cholesterol levels in rats was evaluated in the present study. The products were formulated with defatted soy flour, oat bran, dehydrated onion, soy fiber and spices. Two of

3Corners of the World / Joosep Sang

Index Scriptorium Estoniae

Sang, Joosep

2009-01-01

Arvustused : Robert Jürjendal, Petri Kuljuntausta, David Rothenberg. 3Corners of the World. [Tallinn] : Terra Nova Music, 2008. Nadia ja Fragile. Uhke ali. [Tallinn] : Nadia & Fragile, 2008. UMA. Civitas Soli. [Tallinn] : Elwood, 2008. Uutest heliplaatidest

"Jõulujazzi" kõige "jazzim" kontsert / Joosep Sang

Index Scriptorium Estoniae

Sang, Joosep

2011-01-01

29. novembrist kuni 17. detsembrini toimunud festivali kontsertidest, pikemalt 11. detsembril Vene Kultuurikeskuses kontserdist, kus esinesid trummar Francis Lassus, saksofonist Philippe Sellam ja bassist Linley Marthe

ARSITEKTUR "GUNA DAN CITRA" SANG ROMO MANGUN

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IN MEMORIAM : YUSUF BILYARTA MANGUNWIJAYA

1999-01-01

Full Text Available Yusuf Bilyarta Mangunwijaya is not only recognized as a pastor but also as a cultural observer, writer and architect. The architectural works he produced even touch the marginal people. The work does not only result in the physical building but also the total work of human development, "use" and "image". World Architecture never escapes from Vitruvius trilogy saying : Firmitas, Utilitas and Venustas. In his amazing writing, Mangunwijaya offered a distillation of trilogy (three categories into two categories, 'use' and 'image'. This writing is going to impart how the distillation of three categories becomes a 'two-categories. Abstract in Bahasa Indonesia : Yusuf Bilyarta Mangunwijaya tidak saja dikenal sebagai seorang Pastor, tetapi dia juga seorang budayawan, sastrawan, bahkan arsitek. Karya arsitekturnya menyentuh bahkan sampai ke mereka-mereka yang dipinggirkan (kaum marjinal. Karya arsitekturnya tidak saja sebuah sosok bangunan, tetapi sekaligus karya total dengan pembangunan manusianya, "Guna" dan "Citra". Arsitektur dunia tidak dapat melepaskan diri dari Trilogi Vitruvius: Firmitas, utilitas dan venustas. Dalam karya tulisnya yang luarbiasa, Romo Mangunwijaya menyingkatnya hanya dwilogi saja, Guna dan Citra. Tulisan ini akan membahas bagaimana perasan trilogi itu menjadi dwilogi saja. Kata kunci: Mangunwijaya, Vitruvius, guna, citra.

Staarkleidid / Lee Hanael

Index Scriptorium Estoniae

Hanael, Lee

2008-01-01

10 maailma kuulsamat kleiti kuulusid Marilyn Monroele, Audrey Hepburnile, printsess Dianale, Vivien Leighle, Tina Turnerile, Julia Robertsile, Liz Hurleyle, Sarah Jessica Parkerile, Keira Knightleyle, Jacqueline Kennedyle

Lee Nnukwu Ukochukwu

African Journals Online (AJOL)

User

of his compositions has provoked unusual interest among sacred musicologists and .... The durational values of notes used are a good mix of predominant crotchets, ... training to sing or learn among the local choirs and congregation, Ezenduka's ... songs are said to be “limited to the frequent use of small intervals between.

Fixation of radioactive cerium-144 on white blood cells. Possibilities for use in physiopathology; Fixation du cerium radioactif ({sup 144}Ce) sur les globules blancs. Possibilites d'emploi en physiopathologie

Energy Technology Data Exchange (ETDEWEB)

Aeberhardt, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1958-07-01

From the study of the means of transport of cerium in the blood of various laboratory animals, after intra-venous injection of {sup 144}Ce-{sup 144}Pr without carrier, we have been able to show up the part played by the white cells in the transport of this fission product during its passage in the blood. This observation has led to the study, in vitro, of the methods of cerium fixation on the white cells, with a view to determining the possibilities of using this property for white cell labelling, the methods used up to the present not being entirely satisfactory. Using the method for the separation of the known constituents of the blood proposed by us in 1956, we have studied the cerium fixation under various conditions: - on suspensions of white cells from the rabbit, - on a suspension of human white cells, - on the white cells in whole from the rabbit. (author) [French] L'etude du mode de transport du cerium dans le sang chez differents animaux de laboratoire, apres injection intra-veineuse de {sup 144}Ce-{sup 144}Pr sans entraineur, nous a permis de mettre en evidence le rale des globules blancs dans le transport de ce produit de fission au cours de son passage dans le sang. Cette constatation nous a conduit a etudier, in vitro, les modalites de la fixation du cerium sur les globules blancs afin de preciser les possibilites d'utilisation de cette propriete pour le marquage des globules blancs, les methodes employees jusqu'ici ne donnant pas entiere satisfaction. Disposant de la methode de separation des elements figures du sang que nous avons proposee en 1956, nous avons etudie la fixation du cerium, dans diverses conditions: - sur des suspensions de globules blancs de lapin, - sur une suspension de globules blancs humains, - sur les globules blancs dans le sang total de lapin. (auteur)

Biophysical evaluation of aminoclay as an effective protectant for protein stabilization during freeze-drying and storage

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Song JG

2016-12-01

Full Text Available Jae Geun Song, Sang Hoon Lee, Hyo-Kyung Han College of Pharmacy, Dongguk University, Goyang, South Korea Abstract: This study aimed to evaluate aminoclay (3-aminopropyl-functionalized magnesium phyllosilicate as an effective protectant for the stabilization of protein formulation in freeze-drying. Bovine serum albumin (BSA, as a model protein, was freeze-dried with aminoclay at various concentrations, and the effects of aminoclay on the structural stability of proteins were compared with those of the conventional stabilizers. The structural characteristics of the protein were determined by size exclusion chromatography (SEC, circular dichroism (CD, and Fourier transform infrared (FTIR spectroscopy. Furthermore, physicochemical and morphological characteristics were examined by X-ray powder diffraction (XRPD, differential scanning calorimetry (DSC, and scanning electron microscopy (SEM. XRPD and DSC patterns indicated that the glass transition temperature (Tg of the amorphous formulation of aminoclay mixed with proteins was gradually elevated as the concentration of aminoclay increased. FTIR and CD spectral analysis suggested that the protein structure was well maintained with aminoclay during the freeze-drying process and 3 months of storage at 4°C and 40°C. Furthermore, aminoclay conferred the greatest protection against aggregation and retained the monomer content of BSA even at a high temperature. The morphological characteristics of lyophilized proteins were also well conserved during the storage with aminoclay. These results suggested that aminoclay may be useful as an alternative stabilizer for maintaining the structural stability of protein formulations. Keywords: aminoclay, cryoprotectant, lyoprotectant, freeze-drying, protein, stability

Inheritance of Gelatinization Temperature and Gel Consistency in Rice (Oryza sativa L.)

Science.gov (United States)

Kiani; Sh.; Ranjbar, G. A.; Kazemitabar, S. K.; Jelodar, N. B.; Nowrozi, M.; Bagheri, N.

Gelatinization Temperature (GT) and Gel Consistency (GC) are important traits in determination of rice quality. In present study four rice cultivars namely Sang-e-Tarrom, Gerdeh, IR229 and IRRI2 have been utilized in hybridization as parents. In order to know about genetic characteristics and inheritance of the related traits, direct and reciprocal crosses have been conducted between parents Sang-e-Tarrom and Gerdeh and between IR229 and IRRI2. Inheritance of related traits have been studied in direct and reciprocal hybridizations for hard, intermediate and soft GC, low and high GT. For these evaluations P1, P2, F1, F2, BC1, BC2 generations and their reciprocal crosses have been utilized in present study. Results showed that gene hard GC dominates on intermediate and soft and also intermediate GT dominates on low. From direct and reciprocal crosses Gerdeh x Sang-e-Tarrom and IR229 x IRRI2 have been illustrated that GC and GT expressions are under monogenic control of one major gene corresponding with several modifier genes. Gene dosage effects play a tremendously important and effective role in segregation production among traits. Regarding to the obtained results selections can effectively be performed in later segregation generations for GC and in early generations for GT.

Special Topics in Optical Propagation.

Science.gov (United States)

1981-07-01

station terrestre , le faisoeau tree intenee eerai~t autonntiquement point,& eur La etation ter- reetre par le signal de eondage grtris par ceLle-ci et...d’eepacer de 100 kmn, ou davantage, lee rdp9- teure eur lee cab Lee pour lee commtun-.oation8 eoue-marinee ou terrestree . Noter que Lee fibree et lee cab...nos mesures at qu’il y a aussi une bonne concordance Trlatruectr- vde par lea capteurs de vitesse at Ia turbulence de tempfirature mesurle par Una

Age and growth of European barbel Barbus barbus (Cyprinidae in the small, mesotrophic River Lee and relative to other populations in England

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Vilizzi L.

2013-08-01

Full Text Available Suspected of being in decline, the European barbel Barbus barbus population of the River Lee, a heavily-modified river in South East England, has been the subject of investigations to identify factors associated with perceived population decreases. Population surveys between 1995 and 1999 captured a total of 912 individuals, and standard length (SL frequency analyses between years suggested that the population decline was not related to juvenile recruitment but rather to a recruitment bottleneck in fish 300–340 mm SL. This bottleneck probably results from insufficient available habitat suitable to this size class. Of the sampled fish, scales were removed from 764 and were used in a scale ageing exercise among three researchers. Analyses of their independent age estimates revealed variable interpretations, which arose from uncertainties relating to the difficulty of analysing scale patterns from relatively large, slow-growing fish. Nevertheless, error was within published acceptable margins, and age estimates revealed B. barbus in the river to age 10 years, lower than in many UK rivers. The SL-at-age growth curve was characterised by very fast growth in the initial years of life. Thus, the causal factors in the decline of this B. barbus population appear to have been in the adult life-stage habitat and were likely related to the loss of longitudinal connectivity, mainly due to the presence of water retention structures. River and aquatic ecosystem remediation strategies should therefore focus on enhancing longitudinal connectivity in conjunction with the ongoing improvement of water quality and ecosystem integrity.

Natural course of early COPD

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Rhee CK

2017-02-01

Full Text Available Chin Kook Rhee,1 Kyungjoo Kim,1 Hyoung Kyu Yoon,2 Jee-Ae Kim,3 Sang Hyun Kim,4 Sang Haak Lee,5 Yong Bum Park,6 Ki-Suck Jung,7 Kwang Ha Yoo,8 Yong Il Hwang7 1Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St Mary’s Hospital, 2Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yeouido St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, 3Pharmaceutical Policy Evaluation Research Team, Research Institution, 4Big Data Division, Health Insurance Review and Assessment Service, Wonju, 5Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, St Paul’s Hospital, College of Medicine, The Catholic University of Korea, 6Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Hallym University Kangdong Sacred Heart Hospital, Seoul, 7Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, 8Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea Background and objective: Few studies have examined the natural course of early COPD. The aim of this study was to observe the natural course of early COPD patients. We also aimed to analyze medical utilization and costs for early COPD during a 6-year period. Methods: Patients with early COPD were selected from Korean National Health and Nutrition Examination Survey (KNHANES data. We linked the KNHANES data of patients with early COPD to National Health Insurance data. Results: A total of 2,397 patients were enrolled between 2007 and 2012. The mean forced expiratory volume in 1 second (FEV1 was 78.6%, and the EuroQol five dimensions questionnaire (EQ-5D index value was 0.9. In total, 110 patients utilized health

Produção, composição do leite e constituintes sangüíneos de cabras alimentadas com diferentes volumosos Production, milk composition and blood parameters in goats fed different forages

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L.R. Ribeiro

2008-12-01

Full Text Available Utilizaram-se nove cabras da raça Saanen, para estudar o efeito de dietas compostas por três diferentes fontes de volumosos, feno de alfafa, silagem de milho e feno de aveia, sobre a ingestão de matéria seca, produção e composição do leite e sobre os constituintes sangüíneos, glicose e uréia plasmáticas, em triplo quadrado latino 3x3. Os consumos de matéria seca e proteína bruta dos animais alimentados com feno de alfafa foram mais altos que os à base de silagem de milho (P0,05 das dietas sobre a produção diária de leite (kg/dia, sobre os teores (% de gordura, proteína, lactose e sólidos totais e sobre a contagem de células somáticas (cels/mlx1000. Os animais que consumiram feno de alfafa produziram maiores quantidades (P0,05. Os resultados indicaram que a fonte de volumoso, em rações isoenergéticas e isoproteicas, afeta o desempenho dos animais pela alteração no consumo de MS e PB e produção dos constituintes do leite (kg/dia.Nine Saanen dairy goats, consuming diets composed of three different sources of roughage (alfalfa hay, corn silage, and oat hay were used to study the effect of those diets on the ingestion of dry matter (DM, on milk production, milk composition, and plasmatic glucose and urea levels. The experimental design was a triple latin square 3x3. The intakes of DM and crude protein by the animals fed on alfalfa hay were higher than those fed ration based on corn silage (P0.05 of the diets on the daily milk production and on the fat, protein, lactose, and total solids contents, and on the somatic cells count (SCC, but those cows that received diets with alfalfa hay produced higher amounts (g/day (P0.05. It can be concluded that the forage sources affect the animal performance from changes in both DM and CP intakes and production of milk components (kg/day.

Effects of High-Flow Experiments from Glen Canyon Dam on Abundance, Growth, and Survival Rates of Early Life Stages of Rainbow Trout in the Lees Ferry Reach of the Colorado River

Science.gov (United States)

Korman, Josh; Kaplinski, Matthew; Melis, Theodore S.

2010-01-01

High-flow experiments (HFEs) from Glen Canyon Dam are primarily intended to conserve fine sediment and improve habitat conditions for native fish in the Colorado River as it flows through Grand Canyon National Park, Arizona. These experimental flows also have the potential to affect the rainbow trout (Oncorhynchus mykiss) population in the Lees Ferry tailwater reach immediately below the dam, which supports a highly valued recreational fishery and likely influences the abundance of rainbow trout in Grand Canyon. Understanding how flow regimes affect the survival and growth of juvenile rainbow trout is critical to interpreting trends in adult abundance. This study reports on the effects of HFEs in 2004 and 2008 on early life stages of rainbow trout in the Lees Ferry reach on the basis of monthly sampling of redds (egg nests) and the abundance of the age-0 trout (fertilization to about 1 to 2 months from emergence) and their growth during a 7-year period between 2003 and 2009. Multiple lines of evidence indicate that the March 2008 HFE resulted in a large increase in early survival rates of age-0 trout because of an improvement in habitat conditions. A stock-recruitment analysis demonstrated that age-0 abundance in July 2008 was more than fourfold higher than expected, given the number of viable eggs that produced these fish. A hatch-date analysis showed that early survival rates were much higher for cohorts that hatched about 1 month after the 2008 HFE (about April 15, 2008) relative to those fish that hatched before this date. These cohorts, fertilized after the 2008 HFE, would have emerged into a benthic invertebrate community that had recovered, and was possibly enhanced by, the HFE. Interannual differences in growth of age-0 trout, determined on the basis of otolith microstructure, support this hypothesis. Growth rates in the summer and fall of 2008 (0.44 mm/day) were virtually the same as in 2006 (0.46 mm/day), the highest recorded during 6 years, even though

High frequency plant regeneration from mature seed- derived callus ...

African Journals Online (AJOL)

PRECIOUS

2009-12-15

Dec 15, 2009 ... Ki-Won Lee, Gi Jun Choi, Ki-Yong Kim, Hee Chung Ji, Hyung Soo Park, Sei Hyung Yoon and ... Gramineae family plants (Ha et al., 2001; Dong and Qu, ..... Lee SH, Ahsan N, Lee KW, Kim DH, Lee DG, Kwak SS, Kwon SY, ...

Tormi ja tungi kasinusvanne / Karlo Funk

Index Scriptorium Estoniae

Funk, Karlo, 1971-

1999-01-01

Refereering taani filmikriitiku Peter Schepelerni loengust mängufilmi "Mifune" ("Mifunes sidste sang - dogme 3") linastuse eel Tallinna Kinomajas (režissöör Soren Kragh-Jacobsen : Taani-Rootsi, 1998)

Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers

Directory of Open Access Journals (Sweden)

Yoon S

2014-01-01

Full Text Available Seonghae Yoon,1,* Howard Lee,2,* Tae-Eun Kim,1 SeungHwan Lee,1 Dong-Hyun Chee,3 Joo-Youn Cho,1 Kyung-Sang Yu,1 In-Jin Jang1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, 2Clinical Trials Center, Seoul National University Hospital, 3AbbVie Ltd., Seoul, Republic of Korea *These authors contributed equally to this work Background: This study was conducted to compare the oral bioavailability of an itopride extended-release (ER formulation with that of the reference immediate-release (IR formulation in the fasting state. The effect of food on the bioavailability of itopride ER was also assessed. Methods: A single-center, open-label, randomized, multiple-dose, three-treatment, three-sequence, crossover study was performed in 24 healthy male subjects, aged 22–48 years, who randomly received one of the following treatments for 4 days in each period: itopride 150 mg ER once daily under fasting or fed conditions, or itopride 50 mg IR three times daily in the fasting state. Steady-state pharmacokinetic parameters of itopride, including peak plasma concentration (Cmax and area under the plasma concentration versus time curve over 24 hours after dosing (AUC0–24h, were determined by noncompartmental analysis. The geometric mean ratio of the pharmacokinetic parameters was derived using an analysis of variance model. Results: A total of 24 healthy Korean subjects participated, 23 of whom completed the study. The geometric mean ratio and its 90% confidence interval of once-daily ER itopride versus IR itopride three times a day for AUC0–24h were contained within the conventional bioequivalence range of 0.80–1.25 (0.94 [0.88–1.01], although Cmax was reached more slowly and was lower for itopride ER than for the IR formulation. Food delayed the time taken to reach Cmax for itopride ER, but AUC0–24h was not affected. There were no serious adverse events and both formulations were

Quantum Field Theory in Curved Spacetime

Science.gov (United States)

Reynolds, Sally C.; Gallagher, Andrew

2012-03-01

List of contributors; Foreword J. T. Francis Thackeray; 1. African genesis: an evolving paradigm Sally C. Reynolds; 2. Academic genealogy Peter Ungar and Phillip V. Tobias; Part I. In Search of Origins: Evolutionary Theory, New Species, and Paths into the Past: 3. Speciation in hominin evolution Colin Groves; 4. Searching for a new paradigm for hominid origins in Chad (Central Africa) Michel Brunet; 5. From hominoid arboreality to hominid bipedalism Brigitte Senut; 6. Orrorin and the African ape/hominid dichotomy Martin Pickford; 7. A brief history and results of 40 years of Sterkfontein excavations Ronald J. Clarke; Part II. Hominin Morphology Through Time: Brains, Bodies and Teeth: 8. Hominin brain evolution, 1925-2011: an emerging overview Dean Falk; 9. The issue of brain reorganisation in Australopithecus and early hominids: Dart had it right Ralph L. Holloway; 10. The mass of the human brain: is it a spandrel? Paul R. Manger, Jason Hemingway, Muhammad Spocter and Andrew Gallagher; 11. Origin and diversity of early hominin bipedalism Henry M. McHenry; 12. Forelimb adaptations in Australopithecus afarensis Michelle S. M. Drapeau; 13. Hominin proximal femur morphology from the Tugen Hills to Flores Brian G. Richmond and William L. Jungers; 14. Daily rates of dentine formation and root extension rates in Paranthropus boisei, KNM-ER 1817, from Koobi Fora, Kenya M. Christopher Dean; 15. On the evolutionary development of early hominid molar teeth and the Gondolin Paranthropus molar Kevin L. Kuykendall; 16. Digital South African fossils: morphological studies using reference-based reconstruction and electronic preparation Gerhard W. Weber, Philipp Gunz, Simon Neubauer, Philipp Mitteroecker and Fred L. Bookstein; Part III. Modern Human Origins: Patterns, and Processes: 17. Body size in African Middle Pleistocene Homo Steven E. Churchill, Lee R. Berger, Adam Hartstone-Rose and Headman Zondo; 18. The African origin of recent humanity Milford H. Wolpoff and Sang-Hee Lee

Tõlkesund / Peeter Torop

Index Scriptorium Estoniae

Torop, Peeter, 1950-

2002-01-01

Bibl. lk. 205-206. Kokkuvõte "Forced translation", lk. 362. Sundtõlkimisest Nõukogude Eestis. Ka August Sanga ja Ants Orase tõlketegevusest ning Ch. Baudelaire'i tõlkekogumiku "Kurja lilled" ettevalmistamisest (koost. A. Sang)

SPECTROPHOTOMETRIC STUDIES OF SANGUINARINE-Β-CYCLODEXTRIN COMPLEX FORMATION

Directory of Open Access Journals (Sweden)

Veaceslav Boldescu

2008-06-01

Full Text Available The main aim of this study was to investigate the influence of pH and the presence of hydrophilic polymer polyvinylpyrrolidone on the formation of sanguinarine-β-cyclodextrin (SANG-β-CD inclusion complex. Spectrophotometric studies of the SANG-β-CD systems in the presence and without 0.1 % PVP at the pH 5.0 did not show any evidence of the complex formation. However, the same systems showed several obvious evidences at the pH 8.0: the hyperchromic and the hypochromic effects and the presence of the isosbestic point in the region of 200 – 210 nm. The association constants calculated by three linear methods: Benesi-Hildebrand, Scott and Scatchard, were two times higher for the systems with addition of 0.1% PVP than for the systems without it.

Cicadas (Hemiptera: Cicadidae) from Camiguin of Mindanao Province and Dinagat Island in the Philippines, with a new genus and three new species.

Science.gov (United States)

Lee, Young June; Marshall, David C; Mohagan, Alma; Hill, Kathy B R

2016-03-30

This paper provides the first faunal checklist for the family Cicadidae (Hemiptera) from Camiguin of Mindanao Province and Dinagat Island in the Philippines, comprising ten species belonging to nine genera. Cryptotympana shillana Lee & Mohagan sp. nov., Orientopsaltria inermis (Stål, 1870), Purana crassinotata Lee, 2015, and Huechys parvula Haupt, 1924 are recorded for the first time from Camiguin. Platypleura dinagatensis Lee sp. nov., Chremistica kyoungheeae Lee, 2010, Dundubia vaginata (Fabricius, 1787), Oncotympana pallidiventris Stål, 1870, and Philipsalta nigrina Lee, Marshall & Hill sp. nov. are newly recorded from Dinagat Island. A new genus Philipsalta Lee, Marshall & Hill gen. nov. is erected. Huechysini Distant, 1905 syn. nov. is synonymized with Cicadettini Buckton, 1889. Information on geographic distributions of the Camiguin and Dinagat species is also provided.

[Comparative research into the process of forming the theory of constitution in ancient western medicine and that of four trigrams constitution in Korean medicine and contents of two theories of constitution].

Science.gov (United States)

Park, Joo-Hong

2009-06-01

After conducting comparative research into the process of forming the Theory of Constitution in Ancient Western Medicine and that of Four Trigrams Constitution(Sasang Constitution) in Korean Medicine and contents of two Theories of Constitution in terms of medical history, both theories were found to be formed by an interaction between philosophy and medicine, followed by a combination of the two, on a philosophical basis. The Theory of Constitution in Ancient Western Medicine began with the Theory of Four Elements presented by Empedocles, followed by the Theory of Four Humors presented by Hippocrates and the Theory of Four Temperaments by Galenos, forming and developing the Theory of Constitution. After the Middle Ages, there was no significant advance in the Theory of Constitution by modern times ; however, it developed into the theory of constitution type of Kretschmer and others after the 19th century and into the scientific theory of constitution based on genetics presented by Garrod and others early in the 20th century. The Theory of Four Trigrams Constitution began with the Theory of Constitution in Huangdi Neijing, followed by developments and influences of existing medicine called beginning, restoration, and revival periods and DongeuisoosebowonSaSangChoBonGwon based on the original philosophy of Four Trigrams presented by Lee Je-ma, which is found in GyeokChiGo, DongMuYuGo and so on, ultimately forming and developing into the Theory of Four Trigrams Constitution in Dongeuisoosebowon. Recently, a lot of research is being conducted into making it objective in order to achieve reproducibility in diagnosis and so forth of Four Trigrams Constitution.

Profiling Radar Observations and Numerical Simulations of a Downslope Wind Storm and Rotor on the Lee of the Medicine Bow Mountains in Wyoming

Directory of Open Access Journals (Sweden)

Binod Pokharel

2017-02-01

Full Text Available This study describes a downslope wind storm event observed over the Medicine Bow range (Wyoming, USA on 11 January 2013. The University of Wyoming King Air (UWKA made four along-wind passes over a five-hour period over the mountain of interest. These passes were recognized as among the most turbulent ones encountered in many years by crew members. The MacCready turbulence meter aboard the UWKA measured moderate to severe turbulence conditions on each pass in the lee of the mountain range, with eddy dissipation rate values over 0.5 m2/3 s−1. Three rawinsondes were released from an upstream location at different times. This event is simulated using the non-hydrostatic Weather Research and Forecast (WRF model at an inner- domain resolution of 1 km. The model produces a downslope wind storm, notwithstanding some discrepancies between model and rawinsonde data in terms of upstream atmospheric conditions. Airborne Wyoming Cloud Radar (WCR vertical-plane Doppler velocity data from two beams, one pointing to the nadir and one pointing slant forward, are synthesized to obtain a two-dimensional velocity field in the vertical plane below flight level. This synthesis reveals the fine-scale details of an orographic wave breaking event, including strong, persistent downslope acceleration, a strong leeside updraft (up to 10 m·s−1 flanked by counter-rotating vortices, and deep turbulence, extending well above flight level. The analysis of WCR-derived cross-mountain flow in 19 winter storms over the same mountain reveals that cross-mountain flow acceleration and downslope wind formation are difficult to predict from upstream wind and stability profiles.

On PR group classes and PR algebra membership

International Nuclear Information System (INIS)

Lebedenko, V.M.

1978-01-01

The necessary and sufficient conditions are found for the membership of Lee algebras to PR algebra class, to algebras with commutation relations of [Hsub(i), Hsub(j)]=rsub(ij)Hsub(i) (i< j) type. Due to this, a criterion is obtained for the membership of the Lee froups to PR group classes, connected and simply connected Lee groups, which Lee algebras are PR algebras

Accuracy of advanced cancer patients' life expectancy estimates: The role of race and source of life expectancy information.

Science.gov (United States)

Trevino, Kelly M; Zhang, Baohui; Shen, Megan J; Prigerson, Holly G

2016-06-15

The objective of this study was to examine the source of advanced cancer patients' information about their prognosis and determine whether this source of information could explain racial disparities in the accuracy of patients' life expectancy estimates (LEEs). Coping With Cancer was a prospective, longitudinal, multisite study of terminally ill cancer patients followed until death. In structured interviews, patients reported their LEEs and the sources of these estimates (ie, medical providers, personal beliefs, religious beliefs, and other). The accuracy of LEEs was calculated through a comparison of patients' self-reported LEEs with their actual survival. The sample for this analysis included 229 patients: 31 black patients and 198 white patients. Only 39.30% of the patients estimated their life expectancy within 12 months of their actual survival. Black patients were more likely to have an inaccurate LEE than white patients. A minority of the sample (18.3%) reported that a medical provider was the source of their LEEs; none of the black patients (0%) based their LEEs on a medical provider. Black race remained a significant predictor of an inaccurate LEE, even after the analysis had been controlled for sociodemographic characteristics and the source of LEEs. The majority of advanced cancer patients have an inaccurate understanding of their life expectancy. Black patients with advanced cancer are more likely to have an inaccurate LEE than white patients. Medical providers are not the source of information for LEEs for most advanced cancer patients and especially for black patients. The source of LEEs does not explain racial differences in LEE accuracy. Additional research into the mechanisms underlying racial differences in prognostic understanding is needed. Cancer 2016;122:1905-12. © 2016 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society. This is an open access article under the terms of the Creative Commons

HYDROLOGY, LEE COUNTY, TEXAS

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — Hydrology data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a Flood Insurance...

Erasmusega Eestisse / Merike Lees

Index Scriptorium Estoniae

Lees, Merike, 1976-

2014-01-01

Prantsuse noormees Théo Brunie õppis Lumière’i ülikoolis Lyonis kommunikatsiooni. Aasta Erasmuse vahetusüliõpilasena Balti Filmi- ja Meediakoolis kasutas ta võimalust õppida kommunikatsiooni koos filmitegemisega

Preemptive Approach to Improving Survival in Epithelial Ovarian Cancer

Science.gov (United States)

2012-06-01

Metab 2008;93:3471–7. 692[87] Cho JH, Lee JG, Yang YI, Kim JH, Ahn JH, Baek NI, Lee KT, Choi JH. Eupatilin, a die- 693tary flavonoid , induces G2/M cell...Metab 2008;93:3471–7. 692[87] Cho JH, Lee JG, Yang YI, Kim JH, Ahn JH, Baek NI, Lee KT, Choi JH. Eupatilin, a die- 693tary flavonoid , induces G2/M

Acoustic parameters of infant-directed singing in mothers of infants with down syndrome.

Science.gov (United States)

de l'Etoile, Shannon; Behura, Samarth; Zopluoglu, Cengiz

2017-11-01

This study compared the acoustic parameters and degree of perceived warmth in two types of infant-directed (ID) songs - the lullaby and the playsong - between mothers of infants with Down syndrome (DS) and mothers of typically-developing (TD) infants. Participants included mothers of 15 DS infants and 15 TD infants between 3 and 9 months of age. Each mother's singing voice was digitally recorded while singing to her infant and subjected to feature extraction and data mining. Mothers of DS infants and TD infants sang both lullabies and playsongs with similar frequency. In comparison with mothers of TD infants, mothers of DS infants used a higher maximum pitch and more key changes during playsong. Mothers of DS infants also took more time to establish a rhythmic structure in their singing. These differences suggest mothers are sensitive to the attentional and arousal needs of their DS infants. Mothers of TD infants sang with a higher degree of perceived warmth which does not agree with previous observations of "forceful warmth" in mothers of DS infants. In comparison with lullaby, all mothers sang playsong with higher overall pitch and slower tempo. Playsongs were also distinguished by higher levels of spectral centroid properties related to emotional expressivity, as well as higher degrees of perceived warmth. These similarities help to define specific song types, and suggest that all mothers sing in an expressive manner that can modulate infant arousal, including mothers of DS infants. Copyright © 2017 Elsevier Inc. All rights reserved.

Evaluation of Different Rice Genotypes Tolerance to Saline Irrigation Water

Directory of Open Access Journals (Sweden)

S. Jafari Rad

2015-12-01

Full Text Available To study the responses of seven rice genotypes (Khazar, SA13, Deylam, Sange Joe, Sepidrud, 831 and T5 to different levels of irrigation water salinity, and determining grain yield based on tolerance indices, a CRD based factorial pot experiment with five levels of irrigation water salinity (1, 2, 4, 6 and 8 dSm-1 and three replications was carried out at Rice Research Institute of Iran in 2011. Indices such as SSI, TOL, MP, GMP, HM, STI, YI and YSI were calculated and their correlations with grain yield were estimated for both stress and non-stress conditions. Results indicated significant differences among genotypes and the indices within both conditions. Results also showed that STI and MP indices could be considered as the best indices to screen salt tolerant genotypes. Among the genotypes used in the experiment, T5 produced the highest yield in both non-stress (19.71 g/plant and stress (10.69 g/plant conditions, while the lowest yield in normal (11.84 g/plant and stressful (4.29 g/plant conditions was recorded for Deylam and Khazar, respectively. The highest and the lowest percentage of yield reduction were found in Khazar (69.49% and Sange Joe (31.48% in stressful conditions, respectively. Overall, genotypes T5, 831, Sepidrud and Sange Joe can probably be considered as superior high yielding genotypes in both saline and non-saline conditions for further research.

The association between singing and/or playing a musical instrument and cognitive functions in older adults.

Science.gov (United States)

Mansens, D; Deeg, D J H; Comijs, H C

2017-05-19

Cognitive decline happens to everyone when aging, but to some more than others. Studies with children, adults, and professional musicians suggest that making music could be associated with better cognitive functioning. In older adults however, this association is less well investigated, which is therefore the aim of this study. In this cross-sectional study data from 1101 participants aged 64 and older from the Longitudinal Aging Study Amsterdam were used. Multivariable linear regression analyses were performed to test the association between making music and cognitive functioning and time spent making music and cognitive functioning. ANCOVA analyses were performed to differentiate between participants who made no music, only sang, only played an instrument or both sang and played an instrument in terms of cognitive functioning. Making music was significantly positively associated with letter fluency, learning and attention/short-term memory. Time spent making music yielded no significant results. The ANCOVA analyses showed higher scores for participants who only played an instrument compared to participants who made no music on learning, working memory and processing speed. For processing speed the instrument only group also had a higher score than participants who only sang. Making music at least once every two weeks and especially playing a musical instrument, is associated with better attention, episodic memory and executive functions. The results suggest that making music might be a potential protective factor for cognitive decline; however, to support this notion a longitudinal study design is needed.

Predicting Malaria's Changing Course | IDRC - International ...

International Development Research Centre (IDRC) Digital Library (Canada)

2010-12-09

Dec 9, 2010 ... James Sang of the Kenyan government's Malaria Control Unit says the disease hits ... During the 1998 epidemic, almost four times more school-aged children caught ... This gave birth to the current phase of the project.

Investigation of the Antiasthmatic Properties of Ethanol Extract of ...

African Journals Online (AJOL)

Investigation of the Antiasthmatic Properties of Ethanol Extract of Callophyllis japonica in Mice. WS Park, KS Lee, JH Chun, SH Urm, DS Lee, DY Lee, SG Park, SK Seo, SJ Heo, ZJ Qian, WK Jung, IW Choi ...

Full-Scale Approximations of Spatio-Temporal Covariance Models for Large Datasets

KAUST Repository

Zhang, Bohai; Sang, Huiyan; Huang, Jianhua Z.

2014-01-01

of dataset and application of such models is not feasible for large datasets. This article extends the full-scale approximation (FSA) approach by Sang and Huang (2012) to the spatio-temporal context to reduce computational complexity. A reversible jump Markov

Caractéristiques sociodémographiques associées au risque de ...

African Journals Online (AJOL)

Caractéristiques sociodémographiques associées au risque de transmission du VIH, du VHC et de Treponema pallidum par les donneurs de sang de premier don de Libreville (Gabon) : dynamique trisannuelle des infections de 2009 à 2015.

BLOOD DONATION

CERN Document Server

SC Unit

2008-01-01

A blood donation, organized by EFS (Etablissement Français du Sang) of Annemasse will take place On Wednesday 12 November 2008, from 8:30 to 16:00, at CERN Restaurant 2 If possible, please, bring your blood group Card.

A fixed-dose combination tablet of gemigliptin and metformin sustained release has comparable pharmacodynamic, pharmacokinetic, and tolerability profiles to separate tablets in healthy subjects

Directory of Open Access Journals (Sweden)

Park SI

2015-02-01

Full Text Available Sang-In Park,1,* Howard Lee,1,2,* Jaeseong Oh,1 Kyoung Soo Lim,3 In-Jin Jang,1 Jeong-Ae Kim,4 Jong Hyuk Jung,4 Kyung-Sang Yu1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 2Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Clinical Trials Center, Seoul National University Hospital, Seoul, 3Department of Clinical Pharmacology and Therapeutics, CHA University School of Medicine and CHA Bundang Medical Center, Seongnam, 4LG Life Sciences, Ltd, Seoul, Republic of Korea *These authors contributed equally to this work Background: In type 2 diabetes mellitus, fixed-dose combination (FDC can provide the complementary benefits of correction of multiple pathophysiologic defects such as dysfunctions in glycemic or metabolic control while improving compliance compared with separate tablets taken together. The objective of the study reported here was to compare the pharmacodynamic (PD, pharmacokinetic (PK, and tolerability profiles of gemigliptin and extended-release metformin (metformin XR between FDC and separate tablets.Methods: A randomized, open-label, single-dose, two-way, two-period, crossover study was conducted in 28 healthy male volunteers. Two FDC tablets of gemigliptin/metformin 25/500 mg or separate tablets of gemigliptin (50 mg ×1 and metformin XR (500 mg ×2 were orally administered in each period. Serial blood samples were collected up to 48 hours post-dose to determine dipeptidyl peptidase 4 (DPP-4 activity using spectrophotometric assay and concentrations of gemigliptin and metformin using tandem mass spectrometry. Geometric mean ratios (GMRs of FDC to separate tablet formulations and their 90% confidence intervals (CIs were calculated to compare the PD and PK parameters between the two formulations. Tolerability was assessed throughout the study.Results: The plasma DPP-4 activity�

Hematoma subdural após punção inadvertida da dura-máter: relato de caso

Directory of Open Access Journals (Sweden)

Wallace Lage Duarte

2008-08-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: A cefaléia pós-punção da dura-máter é complicação bastante conhecida das anestesias subaracnóidea e peridural, e o tratamento mais difundido é o tampão sangüíneo. O tampão sangüíneo alivia totalmente a cefaléia na grande maioria dos pacientes, e nos demais não há melhora ou, apenas, melhora parcial. Nesses casos, é prudente buscar diagnósticos diferenciais, como o hematoma subdural ou pneumoencéfalo. Os métodos de imagem são extremamente úteis nessas situações. O objetivo deste relato foi apresentar o caso de um paciente que desenvolveu hematoma subdural intracraniano após punção inadvertida da dura-máter em anestesia peridural. RELATO DO CASO: Paciente do sexo masculino, 47 anos, 147 kg, 1,90 m, estado físico ASA II, foi admitido para realização de dermolipectomia abdominal, após ter-se submetido à gastroplastia redutora. Durante anestesia peridural, houve perfuração acidental da dura-máter. O paciente evoluiu com sintomas de cefaléia pós-punção da dura-máter que foram tratados com tampão sangüíneo, com melhora parcial. Houve, posteriormente, piora da cefaléia, e a ressonância nuclear magnética de encéfalo mostrou hematoma subdural intracraniano, que foi tratado clinicamente. Houve melhora progressiva, com recuperação total após 30 dias. CONCLUSÕES: A ocorrência de hematoma subdural é complicação rara, mas grave da perfuração de dura-máter. O diagnóstico é difícil e deve ser sempre cogitado quando a cefaléia pós-punção da dura-máter não se resolve com o tampão sangüíneo ou piora com sua realização. No esclarecimento diagnóstico é fundamental o auxílio de um método de imagem.

Le groupe de recherches transfusionnelles d’Afrique francophone: bilan des cinq premières années

Science.gov (United States)

Tagny, Claude Tayou; Murphy, Edward L.; Lefrère, Jean-Jacques

2016-01-01

Les travaux de recherches sur la sécurité transfusionnelle en Afrique sub-saharienne sont peu nombreux, souvent limités à des initiatives locales avec des conclusions difficilement représentatives de cette région. Le Groupe de recherches transfusionnelles en Afrique sub-saharienne francophone a été créé en mai 2007 avec pour objectif de développer des stratégies globales d’amélioration de la sécurité transfusionnelle mais adaptables à la situation de chaque pays. Les activités du Groupe à ce jour ont porté essentiellement sur l’obtention de données épidémiologiques et de laboratoire sur la transfusion sanguine et à proposer des stratégies de sécurité transfusionnelle dans le domaine des infections transmissibles par la transfusion. Pour mener à bien ces activités de recherche, le Groupe travaille en étroite collaboration avec les Centres nationaux de transfusion sanguine (CNTS), les Centres régionaux de transfusion sanguine (CRTS), les banques de sang hospitalières (BSH) et les postes de collecte de sang. Pour les 5 premières années, quatre priorités de recherche ont été identifiées: (i) des études descriptives sur les caractéristiques des donneurs de sang et des centres de transfusion; (ii) une estimation du risque résiduel post-transfusionnel des principales infections virales transmissibles par la transfusion; (iii) une analyse des stratégies de sélection médicale des donneurs de sang; et (iv) une description des stratégies de dépistage des ITT et une description du système d’assurance qualité externe existant. Durant cette période, sept projets ont été mis en œuvre au niveau national et publiés et cinq études multicentriques ont été réalisées et publiées. La présente étude rapporte les principales observations et recommandations de ces études. PMID:24360798

REVEAL: Reconstruction, Enhancement, Visualization, and Ergonomic Assessment for Laparoscopy

Science.gov (United States)

2008-08-01

2007) Ergonomic risk of assisting in minimally invasive surgery, Annual conference of SAGES 2008 Park AE, Meenaghan N, Lee TH, Seagull FJ, Lee G...of NOTES techniques: a study of physical and mental workload, body movement and posture Adrian Park, Gyusung Lee, Carlos Godinez, F Jacob Seagull

WA Smith: LP Vosloo, CH van Niekerkand FP Theron Gossypol, a ...

African Journals Online (AJOL)

with the semen of boars (Tso & Lee, 1981), rodents (Hahn,. Rusticus, Probst, Homm & Johnson, 1981), monkeys ... enzymes (Lee & MaIling, 1981; Tso & Lee, 1981;Kennedy, van der Ven, Straus, Bhattacharyya, Waller, ... 1973), Lindsey, Hawkins & Guthrie (1980) showed that diets supplying 24 g free gossypol per lactating ...

Comparative phytochemical evaluation, antimicrobial and ...

African Journals Online (AJOL)

SERVER

2007-08-06

Aug 6, 2007 ... green – blue black coloration) with 0.1% FeCl3, alkaloids based on positive reaction ... positive reactions (violet to blue or green) with acetic anhydride and. H2SO4 ..... 42: 179 –185. Lee KI, Kim YJ, Lee HJ, Lee CY (2001).

Application of a new red carotenoid pigment-producing bacterium ...

African Journals Online (AJOL)

reading 7

pigment-producing bacteria with proteinases was done using hen feces as a target. One isolate ... resulted in significant higher costs of these plant derived materials. ..... Na J-C, Song J-Y, Lee B-D, Lee S-J, Lee C-Y, An G-H (2004). Effect of.

Euterpe edulis Extract but Not Oil Enhances Antioxidant Defenses and Protects against Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet in Rats

Directory of Open Access Journals (Sweden)

Rodrigo Barros Freitas

2016-01-01

Full Text Available We investigated the effects of E. edulis bioproducts (lyophilized pulp [LEE], defatted lyophilized pulp [LDEE], and oil [EO] on nonalcoholic fatty liver disease (NAFLD induced by a high-fat diet (HFD in rats. All products were chemically analyzed. In vivo, 42 rats were equally randomized into seven groups receiving standard diet, HFD alone or combined with EO, LEE, or LDEE. After NAFLD induction, LEE, LDEE, or EO was added to the animals’ diet for 4 weeks. LEE was rich in polyunsaturated fatty acids. From LEE degreasing, LDEE presented higher levels of anthocyanins and antioxidant capacity in vitro. Dietary intake of LEE and especially LDEE, but not EO, attenuated diet-induced NAFLD, reducing inflammatory infiltrate, steatosis, and lipid peroxidation in liver tissue. Although both E. edulis bioproducts were not hepatotoxic, only LDEE presented sufficient benefits to treat NAFLD in rats, possibly by its low lipid content and high amount of phenols and anthocyanins.

Exome Sequence Analysis of 14 Families With High Myopia

DEFF Research Database (Denmark)

Kloss, Bethany A.; Tompson, Stuart W.; Whisenhunt, Kristina N.

2017-01-01

Purpose: To identify causal gene mutations in 14 families with autosomal dominant (AD) high myopia using exome sequencing. Methods: Select individuals from 14 large Caucasian families with high myopia were exome sequenced. Gene variants were filtered to identify potential pathogenic changes. Sang...

Hea ja halb Baudelaire / Lauri Leesi

Index Scriptorium Estoniae

Leesi, Lauri, 1945-

2000-01-01

Arvustus: Baudelaire, Charles. Kurja lilled / koost. August Sang. Tallinn : Perioodika, 1967. (Loomingu Raamatukogu; 35-36) ; Baudelaire, Charles. Väikesed kurja lilled / koost. Indrek Hirv. Tln. : Tänapäev, 2000 ; Baudelaire, Charles. Kurja õied / tlk. Tõnu Õnnepalu. Tln. : Eesti Keele Sihtasutus, 2000

Urologic symptoms and burden of frailty and geriatric conditions in older men: the Aging Study of PyeongChang Rural Area

Directory of Open Access Journals (Sweden)

Jang IY

2018-02-01

Full Text Available Il-Young Jang,1,2 Chang Ki Lee,3 Hee-Won Jung,4,5 Sang Soo Yu,2 Young Soo Lee,1 Eunju Lee,1 Dae Hyun Kim6,7 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea; 2PyeongChang Health Center & County Hospital, PyeongChang, Gangwon-Do, Republic of Korea; 3Goldman Urology Clinic, Seoul, Republic of Korea; 4Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST, Daejeon, Republic of Korea; 5Geriatric Center, Seoul National University Bundang Hospital, Seongnam, Gyeonggi-Do, Republic of Korea; 6Division of Gerontology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; 7Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA Purpose: Frailty is an important consideration in the management of lower urinary tract symptoms and erectile dysfunction in older men; frailty increases vulnerability to treatment-related adverse outcomes, but its burden is not known. The authors aimed to examine the burden of frailty and associated geriatric conditions in community-dwelling older men.Patients and methods: A cross-sectional study was conducted with 492 community-dwelling older men (mean age, 74.2 years; standard deviation, 5.6 years. All the participants were administered the International Prostate Symptom Score (IPSS (range: 0–35 and a five-item version of the International Index of Erectile Function (IIEF-5 (range: 5–25. Frailty phenotype was assessed based on exhaustion, inactivity, slowness, weakness, and weight loss. Prevalence of frailty phenotype and geriatric conditions were assessed by the IPSS severity category (mild, 0–7; moderate, 8–19; severe, 20–35 points and the first IIEF-5 question, which assesses the confidence in erectile function (low, 1–2; moderate, 3; high, 4–5 points.Results: Older men with severe urologic

Three new species of the genus Arge (Hymenoptera: Symphyta: Argidae from South Korea with key to species of the subfamily Arginae

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Jin-Kyung Choi

2016-06-01

Full Text Available Three new species, Arge koreana Wei & Lee sp. nov. from South Korea, Arge pseudorejecta Wei & Lee sp. nov., and Arge shengi Wei & Lee sp. nov. from South Korea and China are described. Keys to known genera of Argidae and known species of Arginae from South Korea are provided.

6th AfSBT CONGRESS ABSTRACTS

African Journals Online (AJOL)

28 déc. 2013 ... however, this strategy was not suitable due to the lack of expertise to develop a .... Gestion des donneurs réguliers - recrutement et rétention. • Gestion ...... Polifique: développement d'une politique du sang qui implique tous.

Caractéristiques, menaces et nécessité de conservation in situ du ...

African Journals Online (AJOL)

SARAH

30 sept. 2015 ... Le contrôle et la limitation de son absorption par le sang zébu sont ... breeding performance of Baoulé taurine cattle, to show its ... zones de savane et dans une moindre mesure ...... conservation et de la gestion des stocks.

in blood transfusion

African Journals Online (AJOL)

gestion de la transfusion des patients se traduit par une diminution spectaculaire de .... lABoRAToRy pERFoRMANCE ChECKs ... CoNTRôlEs DE pERFoRMANCE DE ...... mesure de fournir des packs ayant un faible volume de sang et une.

Analysis of dose, dose-rate and treatment time in the production of injuries by radium treatment for cancer of the uterine cervix; and reply by K.H. Lee

International Nuclear Information System (INIS)

Saunders, J.E.

1977-01-01

The author of the first letter has detected several errors and inconsistencies in the treatment of the data in a recent paper (Lee, K.H., Kagan, A.R., Nussbaum, H., Wollin, M., Winkley, J.H., and Norman, A., 1976, Br. J. Radiol., vol. 49, 430). Valid conclusions about the relative importance of time or dose-rate could not be based on this data. The reply, from one of the authors of the original paper, accepts many of the errata, and enumerates the changes which should be made. Replotting dose-treatment time and dose-dose rate does not however invalidate the conclusion that dose-rate is more important than time in analysing the risk of normal tissue injury. It is not claimed that the Strandqvist separation line in the dose-dose rate plane is better than in the dose-time plane. An improved definition of a region of low injury risk is given by a horizontal line at 4500 rad maximum dose and a vertical line at 60 rad/h maximum dose-rate on the dose-dose rate plot. Dose-rate is expected to be more important than time as a modifying factor of dose, both on the basis of radiobiological data and of clinical experience. Radiotherapists must balance the risks of radiotherapy-tumour recurrence with those of normal tissue injury, and increased attention should therefore be paid to regions of high and low dose-rate. (U.K.)

Fabrication and characterization of anisotropic nanofiber scaffolds for advanced drug delivery systems

Directory of Open Access Journals (Sweden)

Jalani G

2014-05-01

Full Text Available Ghulam Jalani,* Chan Woo Jung,* Jae Sang Lee, Dong Woo Lim Department of Bionano Engineering, College of Engineering Sciences, Hanyang University, Education Research Industry Cluster at Ansan Campus, Ansan, South Korea*These authors contributed equally to this workAbstract: Stimuli-responsive, polymer-based nanostructures with anisotropic compartments are of great interest as advanced materials because they are capable of switching their shape via environmentally-triggered conformational changes, while maintaining discrete compartments. In this study, a new class of stimuli-responsive, anisotropic nanofiber scaffolds with physically and chemically distinct compartments was prepared via electrohydrodynamic cojetting with side-by-side needle geometry. These nanofibers have a thermally responsive, physically-crosslinked compartment, and a chemically-crosslinked compartment at the nanoscale. The thermally responsive compartment is composed of physically crosslinkable poly(N-isopropylacrylamide poly(NIPAM copolymers, and poly(NIPAM-co-stearyl acrylate poly(NIPAM-co-SA, while the thermally-unresponsive compartment is composed of polyethylene glycol dimethacrylates. The two distinct compartments were physically crosslinked by the hydrophobic interaction of the stearyl chains of poly(NIPAM-co-SA or chemically stabilized via ultraviolet irradiation, and were swollen in physiologically relevant buffers due to their hydrophilic polymer networks. Bicompartmental nanofibers with the physically-crosslinked network of the poly(NIPAM-co-SA compartment showed a thermally-triggered shape change due to thermally-induced aggregation of poly(NIPAM-co-SA. Furthermore, when bovine serum albumin and dexamethasone phosphate were separately loaded into each compartment, the bicompartmental nanofibers with anisotropic actuation exhibited decoupled, controlled release profiles of both drugs in response to a temperature. A new class of multicompartmental nanofibers could be

Aberrant brain-stem morphometry associated with sleep disturbance in drug-naïve subjects with Alzheimer's disease

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Lee JH

2016-08-01

Full Text Available Ji Han Lee,1 Won Sang Jung,2 Woo Hee Choi,3 Hyun Kook Lim4 1Washington University in St Louis, St Louis, MO, USA; 2Department of Radiology, 3Department of Nuclear Medicine, 4Department of Psychiatry, Saint Vincent Hospital, College of Medicine, The Catholic University of Korea, Suwon, South Korea Objective: Among patients with Alzheimer’s disease (AD, sleep disturbances are common and serious noncognitive symptoms. Previous studies of AD patients have identified deformations in the brain stem, which may play an important role in the regulation of sleep. The aim of this study was to further investigate the relationship between sleep disturbances and alterations in brain stem morphology in AD.Materials and methods: In 44 patients with AD and 40 healthy elderly controls, sleep disturbances were measured using the Neuropsychiatry Inventory sleep subscale. We employed magnetic resonance imaging-based automated segmentation tools to examine the relationship between sleep disturbances and changes in brain stem morphology.Results: Analyses of the data from AD subjects revealed significant correlations between the Neuropsychiatry Inventory sleep-subscale scores and structural alterations in the left posterior lateral region of the brain stem, as well as normalized brain stem volumes. In addition, significant group differences in posterior brain stem morphology were observed between the AD group and the control group.Conclusion: This study is the first to analyze an association between sleep disturbances and brain stem morphology in AD. In line with previous findings, this study lends support to the possibility that brain stem structural abnormalities might be important neurobiological mechanisms underlying sleep disturbances associated with AD. Further longitudinal research is needed to confirm these findings. Keywords: Alzheimer’s disease, sleep, brain stem, MRI, shape analysis

Lung function and long-term safety of tiotropium/olodaterol in East Asian patients with chronic obstructive pulmonary disease

Directory of Open Access Journals (Sweden)

Bai C

2017-11-01

Full Text Available Chunxue Bai,1 Masakazu Ichinose,2 Sang Haak Lee,3 Kwan Ho Lee,4 Olaf Jöns,5 Ulrich Bothner,6 Yihua Zhao,7 Roland Buhl8 1Department of Pulmonary Medicine, Shanghai Respiratory Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China; 2Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan; 3Department of Internal Medicine, St Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea; 4Department of Internal Medicine, Yeungnam University Medical Center, Daegu, South Korea; 5Department of Medicine TA Respiratory Diseases, 6Department of Pharmacovigilance, Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, Germany; 7Department of Biostatistics and Data Sciences, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA; 8Pulmonary Department, Mainz University Hospital, Mainz, Germany Background and purpose: While the efficacy and safety of combined tiotropium and olodaterol in patients with COPD was established in a large clinical trial program, it is important to assess whether clinical data can be applied to geographic patient groups, particularly for East Asian patients who may have a different phenotypic profile to the global trial population. This study aimed to compare the lung function and safety profiles of tiotropium/olodaterol and monocomponents in East Asian and global populations from the TONADO® trials.Materials and methods: In the replicate, double-blind, parallel-group, active-controlled, randomized, 52-week, Phase III TONADO studies, patients received tiotropium/olodaterol, tiotropium, or olodaterol. We assessed the forced expiratory volume in 1 second (FEV1 area under the curve from 0 to 3 hours (AUC0–3 response and trough FEV1 response at 24 weeks for the approved doses, tiotropium/olodaterol 5/5 µg, tiotropium 5 µg, and olodaterol 5 µg. Treatment-emergent adverse events were recorded throughout treatment and ≤21 days

Mixing, ergodicity and slow relaxation phenomena

Science.gov (United States)

Costa, I. V. L.; Vainstein, M. H.; Lapas, L. C.; Batista, A. A.; Oliveira, F. A.

2006-11-01

Investigations on diffusion in systems with memory [I.V.L. Costa, R. Morgado, M.V.B.T. Lima, F.A. Oliveira, Europhys. Lett. 63 (2003) 173] have established a hierarchical connection between mixing, ergodicity, and the fluctuation-dissipation theorem (FDT). This hierarchy means that ergodicity is a necessary condition for the validity of the FDT, and mixing is a necessary condition for ergodicity. In this work, we compare those results with recent investigations using the Lee recurrence relations method [M.H. Lee, Phys. Rev. B 26 (1982) 2547; M.H. Lee, Phys. Rev. Lett. 87 (2001) 250601; M.H. Lee, J. Phys. A: Math. Gen. 39 (2006) 4651]. Lee shows that ergodicity is violated in the dynamics of the electron gas [M.H. Lee, J. Phys. A: Math. Gen. 39 (2006) 4651]. This reinforces both works and implies that the results of [I.V.L. Costa, R. Morgado, M.V.B.T. Lima, F.A. Oliveira, Europhys. Lett. 63 (2003) 173] are more general than the framework in which they were obtained. Some applications to slow relaxation phenomena are discussed.

Mellem næstsidste sang og offerdød

DEFF Research Database (Denmark)

Bonde, Lars Ole

2010-01-01

Anmeldelse af Ruders' nye opera Dancer in the Dark, som havde urpremiere på Operaen, DKT, i september 2010.......Anmeldelse af Ruders' nye opera Dancer in the Dark, som havde urpremiere på Operaen, DKT, i september 2010....

SERINGUE LOUIS JUBÉ POUR LA TRANSFUSION DU SANG PUR

Directory of Open Access Journals (Sweden)

Academia Nacional de Medicina

2011-01-01

Full Text Available

DENOMINACIÓN:  

Fabricante: Duffaud & Cie

Año: 1924

Medidas: 19,5 x 6 cm

Volumen: 5 cc

Materiales: Acero, vidrio y caucho 

Esta jeringa para transfusión de sangre fue diseñada en Paris por el médico francés, Louis Jubé. Fue desarrollada en 1923, aunque la publicación de la patente sólo se registra hasta el 1 de julio de 1924. 

Este sistema de transfusión de sangre fue el más utilizado en Europa durante la década de los años veinte. La jeringa está compuesta por un cilindro de vidrio y dispone de dos conexiones laterales que, por medio de agujas de diverso calibre, permitían la punción del donante y el receptor. La jeringa más utilizada fue de 5 cc. Para su uso, se debía punzar primero al receptor y una vez canalizada la vena se conectaba al donante. La sangre llenaba el émbolo y luego de varias aspiraciones se trasmitía la sangre al receptor a un ritmo de 5cc cada 3-4 segundos. Este tipo de jeringa podía llegar a permitir transfusiones de 200cc hasta 500cc en algunos casos. Sin embargo, a medida que pasaba el tiempo, la transfusión se dificultaba debido a la coagulación de la sangre y era necesario iniciar el proceso nuevamente. 

DIE PLEK VAN SANG EN MUSIEK IN DIE PROTESTANTSE ...

African Journals Online (AJOL)

Test

Sy moet hierdie opdrag uitvoer deur mid del van die Prediking d.w.s. deur middel van die Woord-vorm, maar ook deur die bediening van die sakramente, dws. deur middel van die vorm van die Daad. Maar nou wil God nie hê dat die Kerk slegs één maal die Evangelie sal predik en die mense sal doop om hulle daarna.

Sappho. A New Translation of the Complete Works

NARCIS (Netherlands)

Rayor, D.J.; Lardinois, A.P.M.H.

2014-01-01

Sappho, the earliest and most famous Greek woman poet, sang her songs around 600 BCE on the island of Lesbos. Of the little that survives from the approximately nine papyrus scrolls collected in antiquity, all is translated here: substantial poems, fragments, single words - and, notably, five

In situ rumen degradability characteristics of rice straw, soybean ...

African Journals Online (AJOL)

In situ rumen degradability characteristics of rice straw, soybean curd residue and peppermint (Mentha piperita) in Hanwoo steer (Bos Taurus coreanae). Byong Tae Jeon, KyoungHoon Kim, Sung Jin Kim, Na Yeon Kim, Jae Hyun Park, Dong Hyun Kim, Mi Rae Oh, Sang Ho Moon ...

AHP 39: BEING ANYTHING AND GOING ANYWHERE: AN A MDO TIBETAN AUTO-SONG-OGRAPHY

Directory of Open Access Journals (Sweden)

Sangs rgyas bkra shis སངས་རྒྱས་བཀྲ་ཤིས།

2016-03-01

Full Text Available Sangs rgyas bkra shis describes singing in a pastoral community in Mtsho sngon Province, China. Performances at weddings, family gatherings, neighborhood gatherings, and on the grassland while herding are richly contextualized. Musical instruments, what it means to be a singer, the worries of singing publicly, the introduction of electricity and cell phones and their impact on singing, singing competitions, generational preference for song types, recent prohibitions on alcohol consumption, and access to social media are examined. Musical notation, oral and literary texts, and English translation are given. Sang rgyas bkra shis’ BEING ANYTHING AND GOING ANYWHERE is a rich, vivid, and immensely informative account of songs and singing in Amdo. Written from personal experience but with a rigorous coverage and excellent illustration of music, texts, and contexts, this book is the next best thing to actually visiting Gcan tsha County. A beautiful and invaluable resource.--Anna Morcom, University of London

“We have the right not to be ‘rescued’...”*: When Anti-Trafficking Programmes Undermine the Health and Well-Being of Sex Workers

Directory of Open Access Journals (Sweden)

Aziza Ahmed

2012-06-01

Full Text Available This paper highlights the impact of raid, rescue, and rehabilitation schemes on HIV programmes. It uses a case study of Veshya Anyay Mukti Parishad (VAMP, a sex workers collective in Sangli, India, to explore the impact of anti-trafficking efforts on HIV prevention programmes. The paper begins with an overview of the anti-trafficking movement emerging out of the United States. This U.S. based anti- trafficking movement works in partnership with domestic Indian anti- trafficking organisations to raid brothels to “rescue and rehabilitate” sex workers. Contrary to the purported goal of assisting women, the anti-trafficking projects that employ a raid, rescue, and rehabilitate model often undermine HIV projects at the local level, in turn causing harm to women and girls. We examine the experience of one peer educator in Sangli to demonstrate and highlight some of the negative consequences of these anti-trafficking efforts on HIV prevention programmes.

"¿Entiendes, con seguridad, lo que lees?" Hch 8, 30 Caminos de la hermenéutica de [en] la Escritura

Directory of Open Access Journals (Sweden)

Ignacio Chuecas Saldías

2005-01-01

Full Text Available El presente artículo busca ser una contribución para una hermenéutica bíblica práctica: es decir, no mira hacia la teoría de la interpretación, sino más bien hacia la praxis actual, especialmente en el campo de los estudios sincrónicos. Al mismo tiempo, pretende invitar al lector a conocer los métodos hermenéuticos propios de la tradición del Nuevo Testamento. Es a través de los caminos del midrash judeocristiano que nos acercamos a la praxis hermenéutica de los escritores bíblicos. El objetivo propuesto es llevado a cabo empleando como guía hermenéutica, a la vez que como laboratorio donde se ejemplifican los principios expuestos, el texto bíblico del encuentro del evangelista Felipe y el ministro de la reina de Etiopía (Hechos 8, 20-40. La pregunta de Felipe sirve de leitmotiv a este proceso: ¿entiendes, con certeza, lo que lees? Hermenéutica bíblica es siempre una manera de leer donde la escritura se interpreta a sí misma. El artículo presta especial atención a las categorías y herramientas de interpretación que se han desarrollado a partir de las nuevas impostaciones literarias en el campo de la exégesis bíblicaThe article attempts to make a contribution to the practical biblical hermeneutics focusing on the actual praxis, especially exploring the field of synchronic studies, rather than on the theory of interpretation. It also aims at offering an insight to the hermeneutic methods of the New Testament tradition, approaching the hermeneutic praxis of the biblical writers through the judeo-christian midrash paths. The accomplish such an objective, the author focuses on the biblical text of Philip's encounter with the minister of the queen of Ethiopia (Acts, 8, 20-40 as the hermeneutic guide and source to illustrate the principles being exposed. Philip's question "Can you really understand what you are reading?" serves as leitmotif to this process, as the biblical hermeneutics is a way of reading inwhich the

"O thou great God of trade, O subject of my song!" Dutch poems on trade, 1770-1830

NARCIS (Netherlands)

Johannes, Gert Jan; Leemans, Inger

Between 1770 and 1830, the Dutch urgently sought to remedy the decline of their economy. Not only learned societies supplied suggestions, but also poets. Around 15 remarkably sizable poems were published that sang the praises of trade and its history. In these poems, trade was put forward as a

A Practitioner’s Perspective on the Kenya I and Kenya II Cases before the ICC

NARCIS (Netherlands)

Mc Gonigle, B.N.

2014-01-01

On 10 September 2013 the International Criminal Court (ICC) began hearing a case against William Ruto, Deputy President of the Republic of Kenya, and Joshua Sang. The related case against the President of Kenya, Uhuru Muigai Kenyatta, was scheduled to begin in November 2013 but has since been

Efficient Training Methods for Conditional Random Fields

Science.gov (United States)

2008-02-01

Learning (ICML), 2007. [63] Bruce G. Lindsay. Composite likelihood methods. Contemporary Mathematics, pages 221–239, 1988. 189 [64] Yan Liu, Jaime ...Conference on Machine Learning (ICML), pages 737–744, 2005. [107] Erik F. Tjong Kim Sang and Sabine Buchholz. Introduction to the CoNLL-2000 shared task

Avgang 2017: Sommerkonsert i Aulaen

OpenAIRE

2017-01-01

Avgangsstudenter fra MA2 opera og studenter fra MA1 holder konsert med sang fra operaer, lieder og fra operetter. MA2 sangere: Hanne Korsbrekke Askeland, Dagfinn Andersen, Sara Aasen. MA1 sangere: Eilert Egil Taugbøl Hasseldal, Marcela Randem, Nora Oleanne Sårheim, Tina Therese Tuven

Bulletin of Materials Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

Author Affiliations. N D Sang1 P H Quang2 L T Tu2 D T B Hop2. National University of Civil Engineering, 55 Giai Phong Street, Hai Ba Trung, Hanoi, Vietnam; Hanoi University of Science, Vietnam National University, Hanoi, 334 Nguyen Trai, Thanh Xuan, Hanoi, Vietnam ...

La gouvernance de la sécurité au Mali : entre libéralisation et/ou ...

African Journals Online (AJOL)

pan entier de l'économie de la gouvernance du secteur de la sécurité. Nous identifions ...... de la sécurité et le transfert de certains instruments de politique publique en .... Sacrifices, prix du sang, eau du maître : fondation des territoires de.

Évolution De La Prevalence Des Infections Virales Transmissibles ...

African Journals Online (AJOL)

Évolution De La Prevalence Des Infections Virales Transmissibles Par Transfusion Chez Les Donneurs De Sang Du Cnts De Cote D'ivoire De 2000 A 2010. B Dembélé, KA Inwoley, MK Diane, R Affi-Aboli, AS Abisse, BL Siransy, S Konate, AS Oga, D Sawadogo ...

Contribution to research on the metabolism of fission product. Studies on the physico-chemical state and the metabolic fate of radio-cerium solution; Contribution a l'etude du metabolisme des produits de fission. Recherches sur l'etat physico-chimique et le devenir metabolique des solutions de radiocerium

Energy Technology Data Exchange (ETDEWEB)

Aeberhardt, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1961-07-01

This paper describes a study of the physico-chemical state of radio-cerium in dilute solutions on the tracer scale, as a function of the pH of the solution. The way in which this radioelement is transported in the blood is studied in vitro and in vivo, with reference to the ionic or colloidal state of the radio-cerium used. The distribution of cerium amongst the various components of the blood is studied by a new method of blood fractionation and by paper electrophoresis. Evidence of a cerium globulin connection is shown in the case of ionic cerium. A study of the initial distribution of radio-cerium in rats, after intravenous administration of ionic or colloidal solutions, shows considerable differences according to the physico-chemical state of the cerium injected. (author) [French] Ce travail presente une etude de l'etat physico-chimique du radiocerium en solutions diluees a l'echelle des indicateurs, en fonction du pH de la solution. En fonction de l'etat ionique ou colloidal du radiocerium utilise, le mode de transport de ce radioelement dans le sang est etudie in vitro et in vivo. La distribution du cerium entre les differents constituants du sang est etudiee par une methode nouvelle de fractionnement du sang et par electrophorese sur papier. L'existence d'une liaison cerium-globuline est mise en evidence dans le cas du cerium ionique. L'etude de la distribution initiale du radiocerium, chez le rat apres administration par voie veineuse de solutions ionique ou colloidale, montre des differences importantes en fonction de l'etat physico-chimique du cerium injecte. (auteur)

[Birth and succession of a current of learning in Korean medicine: the supporting yang current of learning].

Science.gov (United States)

Oh, Chaekun

2014-04-01

In this study, I aim to reveal how Lee Gyoojoons medicine has given birth to a current of learning, the supporting yang current of learning, and describe its historical significance. Before anything, I'd like to throw the question of whether if there were any currents within the traditional Korean medicine. There are no records of medical currents being widely discussed until now in medical history of Korea; however, the current of Lee Jema's sasang medicine is the most noticeable one. Among the contemporaries of Lee Jema, during the late Chosun, there was also another famed medical practitioner called Lee Gyoojoon. Lee Gyoojoon mainly practiced his medicine within Pohang, Gyeongsangbuk-do area, his apprentices have formed a group and have succeeded his medical practice. Based on the analyses of Lee Gyoojoon's apprentices and the Somun Oriental Medical Society, which is known as a successor group to Lee Gyoojoon's medicine today, they are fully satisfying the five requirements to establish a medical current: first, they held Lee Gyoojoon as the first and foremost, representative practitioner of their current; second, they advocate the supporting yang theory suggested by Lee Gyoojoon, which is originated from his theory of Mind; third, books such as the Major Essentials of Huangdi's Internal Classic Plain Questions, and the Double Grinded Medical Mirror, were being used as the main textbooks to educate their students or to practice medicine. Fourth, Lee Gyoojoon's medical ideas were being transcended quite clearly within his group of apprentices, including Seo Byungoh, Lee Wonse, and the Somun Oriental Medical Society. Fifth, Lee Gyoojoon's apprentices were first produced through the Sukgok School, however, nowadays they are being produced through medical groups formed by Lee Wonse, the Somun Oriental Medical Society, regarding the propagation of medical theories, compilation of textbooks, publication of academic journals, etc. Then, what do the existence of the

Portrait of Henry J. Lee

OpenAIRE

Wallace, Elizabeth (Artist)

2012-01-01

Part of the Virginia Tech Pastel Portrait Collection, Blacksburg, this is one of the original set of portraits which were distributed to the loved ones of the victims, or stored for those who might want them at a later date.

HYDRAULICS, LEE COUNTY, GEORGIA, USA

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — Recent developments in digital terrain and geospatial database management technology make it possible to protect this investment for existing and future projects to...

ORTHOIMAGERY, LEE COUNTY, GA, USA

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — Digital orthographic imagery datasets contain georeferenced images of the Earth?s surface, collected by a sensor in which object displacement has been removed for...

Model for Atmospheric Propagation of Spatially Combined Laser Beams

Science.gov (United States)

2016-09-01

NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS MODEL FOR ATMOSPHERIC PROPAGATION OF SPATIALLY COMBINED LASER BEAMS by Kum Leong Lee September...MODEL FOR ATMOSPHERIC PROPAGATION OF SPATIALLY COMBINED LASER BEAMS 5. FUNDING NUMBERS 6. AUTHOR(S) Kum Leong Lee 7. PERFORMING ORGANIZATION NAME(S) AND...BLANK ii Approved for public release. Distribution is unlimited. MODEL FOR ATMOSPHERIC PROPAGATION OF SPATIALLY COMBINED LASER BEAMS Kum Leong Lee

Comparative study on hematological parameters of farmed matrinxã, Brycon amazonicus Spix and Agassiz, 1829 (Characidae: Bryconinae with others Bryconinae species Estudo comparativo sobre parâmetros hematológicos de matrinxã Brycon amazonicus Spix e Agassiz, 1892(Characidae: Bryconinae criados em cativeiro, com outras espécies de Bryconinae

Directory of Open Access Journals (Sweden)

Marcos Tavares-Dias

2008-12-01

Full Text Available The aim of this study was not only to determine the red blood cells parameters, thrombocyte and leukocyte counts in farmed Brycon amazonicus (matrinxã, to compare these parameters among Bryconinae species from literature, and also to investigate the presence of special granulocytic cells in these fish. The results of the blood cells parameters here established for farmed B. amazonicus, a species of great economic importance in Brazilian aquaculture, could help a better understanding of the blood features in natural populations of this Amazon species. Blood parameters varied between Bryconinae species investigated, mainly the red blood cell counts, hemoglobin, hematocrit and mean corpuscular volume (MCV. The presence of the blood granulocytes, neutrophils and heterophils in matrinxã suggest that both leukocytes can be a characteristic for Bryconinae family. Furthermore, it indicates that the existence of special granulocytic cells in the blood of Bryconinae species from literature is an artifact, and this was herein discussed.O objetivo deste estudo foi determinar os parâmetros eritrocíticos, as contagens de trombócitos e de leucócitos de espécimes de Brycon amazonicus (matrinxã, criados em cativeiro e compará-los com aqueles descritos na literatura para outras espécies de Bryconinae. Além disso, foi ainda investigada a presença de células granulocíticas especiais nestes peixes. Os resultados dos parâmetros sangüíneos apresentados para B. amazonicus podem ajudar a entender melhor as características sangüíneas em população natural desta espécie de grande importância para a aqüicultura brasileira. Os parâmetros sangüíneos das espécies de Bryconinae investigadas apresentaram variação interespecíficas principalmente a contagem de eritrócitos, hemoglobina, hematócrito e volume corpuscular médio (VCM. A presença dos granulócitos sangüíneos, neutrófilos e heterófilos em matrinxã sugere que esta pode ser uma

There's more to the picture than meets the eye

DEFF Research Database (Denmark)

Svendsen, Gunnar Lind Haase; Sørensen, Jens Fyhn Lykke

2007-01-01

observation, most economists have failed to see that ‘there's more to the picture than meets the eye', as Neil Young once sang. We use statistical, historical and fieldwork data from two Danish, marginal rural communities both rich on intangible capital. This to show how intangible capital in the form...

The STruCTure and dynamiCS of LuTher'S CaTeChiSm

African Journals Online (AJOL)

except the Bible. To put it poetically: “its rhythms sang themselves into the hearts of Lutherans everywhere” (Wiencke 1965:379). Consulting the Tanner- collection in the ... territories in america carried in their saddlebags just a few copies of Luther's .... appeared in 1529 in book form, decorated with biblical engravings and.

59 forskellige kronikker, klummer mv. med hver deres titel i Berlingske, JP og Kristeligt Dagblad

DEFF Research Database (Denmark)

Sørensen, Lars Hovbakke

2017-01-01

og julemiddagen Den 16. december: Julens sange Den 17. december: Julebukken Den 18. december: ”Rudolf med den røde tud” Den 19. december: Kravlenisserne Den 20. december: Glöggen og juleøllet Den 21. december: Adventsstjernen Den 22. december: Julemarkedet Den 23. december: Walt Disneys juleshow Den...

Parâmetros ruminal, sangüíneo e urinário e digestibilidade de nutrientes em novilhas leiteiras recebendo diferentes níveis de monensina Effects of different dietary levels of monensin on nutrient digestibility and on ruminal, blood and urinary metabolites in dairy heifers

Directory of Open Access Journals (Sweden)

Marcus Vinicius Morais de Oliveira

2005-12-01

Full Text Available Objetivou-se verificar a influência da inclusão de diferentes níveis do ionóforo monensina sódica na dieta sobre os parâmetros ruminal, sangüíneo e urinário e a digestibilidade aparente em novilhas leiteiras. Foram coletadas amostras de líquido ruminal (imediatamente antes e duas horas após a alimentação, sangue, urina e fezes de 28 novilhas da raça Holandesa mantidas em regime de confinamento por 84 dias. As dietas possuíam 32,84% de concentrado (grão de milho, farelo de soja, uréia e mistura mineral, 33,58% de silagem de milho e 33,58% de cana-de-açúcar na matéria seca. Os níveis de ionóforo avaliados foram 0, 14, 28 e 42 mg de monensina/kg de matéria seca da dieta. O experimento foi instalado conforme delineamento inteiramente casualizado, com quatro tratamentos e sete repetições, realizando-se estudos de regressão e contrastes ortogonais. Antes da alimentação, a monensina não influenciou o pH ruminal e a concentração de amônia e dos ácidos acético, propiônico e butírico, mas promoveu redução da relação acetato:propionato. Duas horas após a alimentação, verificou-se redução do pH e da relação acetato:propionato; e aumento da concentração de ácido propiônico. O estudo de contrastes revelou que ocorreu diminuição da concentração de amônia antes da alimentação. Não foram verificadas mudanças significativas nas concentrações de glicose e uréia sangüínea. A monensina também não influenciou os consumos de matéria seca (MS, matéria orgânica, proteína bruta, extrato etéreo (EE, carboidratos totais (CHOT e fibra em detergente neutro. As digestibilidades da MS, EE e CHOT e a perda de nitrogênio urinário apresentaram respostas quadráticas.The objective of this trial was to study the effects of different dietary levels of the ionophore monensin on apparent digestibility of nutrients and on ruminal, blood, and urinary metabolites in dairy heifers. Samples of ruminal fluid (pre

Effect of constitutive inactivation of the myostatin gene on the gain in muscle strength during postnatal growth in two murine models.

Science.gov (United States)

Stantzou, Amalia; Ueberschlag-Pitiot, Vanessa; Thomasson, Remi; Furling, Denis; Bonnieu, Anne; Amthor, Helge; Ferry, Arnaud

2017-02-01

The effect of constitutive inactivation of the gene encoding myostatin on the gain in muscle performance during postnatal growth has not been well characterized. We analyzed 2 murine myostatin knockout (KO) models, (i) the Lee model (KO Lee ) and (ii) the Grobet model (KO Grobet ), and measured the contraction of tibialis anterior muscle in situ. Absolute maximal isometric force was increased in 6-month-old KO Lee and KO Grobet mice, as compared to wild-type mice. Similarly, absolute maximal power was increased in 6-month-old KO Lee mice. In contrast, specific maximal force (relative maximal force per unit of muscle mass was decreased in all 6-month-old male and female KO mice, except in 6-month-old female KO Grobet mice, whereas specific maximal power was reduced only in male KO Lee mice. Genetic inactivation of myostatin increases maximal force and power, but in return it reduces muscle quality, particularly in male mice. Muscle Nerve 55: 254-261, 2017. © 2016 Wiley Periodicals, Inc.

Study guide for Statistics for business and financial economics a supplement to the textbook by Cheng-Few Lee, John C. Lee and Alice C. Lee

CERN Document Server

Moy, Ronald L; Kao, Lie Jane

2015-01-01

This Study Guide accompanies Statistics for Business and Financial Economics, 3rd Ed. (Springer, 2013), which is a business statistics textbook that uses finance, economics, and accounting data throughout the book. This Study Guide contains unique chapter reviews for each chapter in the textbook, formulas, examples, and additional exercises to enhance topics and their application. Solutions are included so students can evaluate their own understanding of the material. With more real-life data sets than the other books on the market, this study guide and the textbook that it accompanies, give readers all the tools they need to learn material in class and on their own. The topics covered are immediately applicable to facing uncertainty and the science of good decision making in financial analysis, econometrics, auditing, production, operations, and marketing research. Students in business degree programs will find this material particularly useful in their other courses and future work.

The relationship between fat depot-specific preadipocyte differentiation and metabolic syndrome in obese women

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N V Mazurina

2013-03-01

Full Text Available Реферат по материалам статьи The relationship between fat depot-specific preadipocyte differentiation and metabolic syndrome in obese women. Park HТ, Lee ES, Cheon EP, Lee DR, Yang K-S, Kim YT, Hur JY, Kim SH, Lee KW, Kim T. Clinical Endocrinology 2012; 76, 59-66.

A field study of flow turbulence and sediment transport dynamics on a beach surface in the lee of a coastal foredune under offshore winds

Science.gov (United States)

Baas, A. C.; Jackson, D.; Cooper, J. A.; Lynch, K.; Delgado-Fernandez, I.; Beyers, M.; Lee, Z. S.

2010-12-01

The past decade has seen a growing body of research on the relation between turbulence in the wind and the resultant transport of sediment over active sand surfaces. Widespread use of sonic anemometry and high-frequency sand transport sensors and traps have facilitated recent field studies over dunes and beach surfaces, to move beyond monitoring of mean wind speed and bulk transport to more detailed measurements at much higher spatio-temporal resolutions. In this paper we present results of a field study conducted in the recirculation flow and re-attachment zone on a beach behind a foredune at Magilligan Strand, Northern Ireland. The offshore winds over the foredune at this site are associated with flow separation and reversal located over the beach surface in the lee of the dune row, often strong enough to induce sand transport toward the toe of the foredune (‘against’ the overall offshore flow). The re-attachment and recirculation zone are associated with strongly turbulent fluid flow and complex streamlines that do not follow the underlying topography. High frequency (25 Hz) wind and sand transport data were collected at a grid of point locations distributed over the beach surface between 35 m to 55 m distance from the 10 m high dune crest, using ultrasonic anemometers at 0.5 m height and co-located load cell traps and Safires at the bed surface. The wind data are used to investigate the role of Reynolds shear stresses and quadrant analysis techniques for identifying burst-sweep events in relation to sand transport events. This includes an assessment of the issues involved with data rotations for yaw, pitch, and roll corrections relative to complex flow streamlines, and the subsequently derived turbulence parameters based on fluctuating vector components (u’, v’, w’). Results illustrate how transport may exist under threshold mean velocities because of the role played by coherent flow structures, and the findings corroborate previous findings that

Waste conversion into n-caprylate and n-caproate: resource recovery from wine lees using anaerobic reactor microbiomes and in-line extraction

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Leo A. Kucek

2016-11-01

Full Text Available To convert wastes into sustainable liquid fuels and chemicals, new resource recovery technologies are required. Chain elongation is a carboxylate-platform bioprocess that converts short-chain carboxylates (SCCs (e.g., acetate C2 and n-butyrate C4 into medium-chain carboxylates (MCCs (e.g., n-caprylate C8 and n-caproate C6 with hydrogen gas as a side product. Ethanol or another electron donor (e.g., lactate, carbohydrate is required. Competitive MCC productivities, yields (product vs. substrate fed, and specificities (product vs. all products were only achieved previously from an organic waste material when exogenous ethanol had been added. Here, we converted a real organic waste, which inherently comprised of ethanol, into MCCs with n-caprylate as the target product. We used wine lees, which consisted primarily of settled yeast cells and ethanol from wine fermentation, and produced MCCs with a reactor microbiome. We operated the bioreactor at a pH of 5.2 and with continuous in-line extraction and achieved a MCC productivity of 3.9 g COD/L-d at an organic loading rate of 5.8 g COD/L-d, resulting in a promising MCC yield of 67% and specificities of 36% for each n-caprylate and n-caproate (72% for both. Compared to all other studies that used complex organic substrates, we achieved the highest n-caprylate-to-n-caproate product ratio of 1.0 (COD basis, because we used increased broth-recycle rates through the forward membrane contactor, which improved in-line extraction rates. Increased recycle rates also allowed us to achieve the highest reported MCC production flux per membrane surface area thus far (20.1 g COD/m2-d. Through microbial community analyses, we determined that an operational taxonomic unit (OTU for Bacteroides spp. was dominant and was positively correlated with increased MCC productivities. Our data also suggested that the microbiome may have been shaped for improved MCC production by the high broth-recycle rates. Comparable abiotic

Eesti lüürika aastal 1936/ Ants Oras

Index Scriptorium Estoniae

Oras, Ants, 1900-1982

2009-01-01

Pikemalt käsitletakse järgnevaid autoreid ja nende teoseid: Johannes Semper "Tuuleratas", Johannes Barbarus "Memento", Hendrik Adamson "Mälestuste maja", Jaan Kärner "Sõna-süte", Juhan Sütiste "Sadamad ja saared", Betti Alver "Tolm ja tuli", August Sang "Üks noormees otsib õnne", Juhan Sinimäe "Isamaa"

Browse Title Index

African Journals Online (AJOL)

Items 6201 - 6250 of 11090 ... Byong Tae Jeon, KyoungHoon Kim, Sung Jin Kim, Na Yeon Kim, Jae Hyun Park, Dong Hyun Kim, Mi Rae Oh, Sang Ho Moon. Vol 10, No 65 (2011), In vitro activity of certain antimicrobial agents in combination with Augouardia letestii hexane extracts against methicillin-resistant Staphylococcus ...

NON-GRAMMATICAL APOPHONY IN ENGLISH.

Science.gov (United States)

WESCOTT, ROGER W.

AN APOPHONE MAY BE DEFINED GENERALLY AS A POLYSYLLABIC VOWEL SEQUENCE SUCH THAT EACH CONTAINED VOWEL IS LOWER OR MORE RETRACTED THAN THE VOWEL WHICH PRECEDES IT --"SING, SANG, SUNG," AND "CLINK, CLANK, CLUNK" ARE EXAMPLES IN ENGLISH. FOR NEARLY EVERY CASE OF GRAMMATICAL APOPHONY IN ENGLISH THERE IS A NON-GRAMMATICAL (YET…

Gun Violence and the Meaning of American Schools

Science.gov (United States)

Warnick, Bryan R.; Kim, Sang Hyun; Robinson, Shannon

2015-01-01

In the United States, targeted school shootings have become a distinct genre of violence. In this essay, Bryan Warnick, Sang Hyun Kim, and Shannon Robinson examine the social meanings that exist in American society that might contribute to this phenomenon, focusing on the question: "Why are schools conceptualized as appropriate places to…

Pathogenetic Influences of Human Herpesvirus 8 (HHV-8) in Prostate Cancer Progression

Science.gov (United States)

2012-05-25

Science 1974;186:1213-1215. 11. Wilson JD, Griffin JE, Leshin M, George FW. Role of gonadal hormones in development of the sexual phenotypes. Hum Genet... Cantor A, Muro-Cacho C, Livingston S, Karras J, Pow-Sang J, Jove R. Constitutive activation of Stat3 in human prostate tumors and cell lines: direct

233 Efficacité de la reproduction en relation avec les anomalies ...

African Journals Online (AJOL)

HP COMPAQ

victimes d'un disfonctionnement de reproduction et l'autre des vaches sans .... été utilisée en croisement d'absorption pour la création en Russie d'un type de race pie ... hepariné en 3 gouttes pour éviter la coagulation du sang, stimulés par la ...

Special Issue on Global Health Disparities Focus on Cancer.

Science.gov (United States)

Lee, Haeok

2016-01-01

Haeok Lee, PhD, RN, FAAN who is a Korean-American nurse scientist, received her doctor al degree from the Nursing Physiology Department, College of Nursing, University of California, San Francisco (UCSF), in 1993, and her post doctor al training from College of Medicine, UCSF. Dr. Lee worked at Case Western Reserve University and University of Colorado Health Sciences Center. She has worked at the UMass Boston since 2008. Dr. Lee has established a long-term commitment to minority health, especially Asian American Pacific Islanders, as a community leader, community health educator, and community researcher, and all these services have become a foundation for her community-based participatory research. Dr. Lee's research addresses current health problems framed in the context of social, political, and economic settings, and her studies have improved racial and ethnic data and developed national health policies to address health disparities in hepatitis B virus (HBV) infections and liver cancer among minorities. Dr. Lee's research, which is noteworthy for its theoretical base, is clearly filling the gap. Especially, Dr. Lee's research is beginning to have a favorable impact on national and international health policies and continuing education programs directed toward the global elimination of cervical and liver cancer-related health disparities in underserved and understudied populations.

77 FR 17012 - Foreign-Trade Zone 158-Vicksburg/Jackson, MS; Application for Manufacturing Authority; Morgan...

Science.gov (United States)

2012-03-23

... Road within the Tupelo Lee Industrial Park (Site 17) in Verona, Lee County, Mississippi. The... procedures would help improve the facility's international competitiveness. In accordance with the Board's...

Evaluation of the Protective Efficacy of Recombinant Vesicular Stomatitis Virus Vectors Against Marburg Hemorrhagic Fever in Nonhuman Primate Models

Science.gov (United States)

2007-01-19

et al. 1996; Lee, Groebner et al. 2006; Jones, Feldmann et al. 2005). However, NHPs display disease characteristics such as clinical disease, and...2003; Jones, Feldmann et al. 2005; Wang, Schmaljohn et al. 2006; Lee, Groebner et al. 2006). Among the successful vaccine platforms evaluated in...primary influenza infection and helps to prevent reinfection." J Immunol 175(9): 5827-38. 152 Lee, J. S., J. L. Groebner , et al. (2006). "Multiagent

Desempenho e parâmetros sangüíneos de eqüinos em crescimento submetidos a dietas com diferentes níveis de farelo de canola Performance and blood parameters of growing equine fed diets with different levels of canola meal

Directory of Open Access Journals (Sweden)

Kátia de Oliveira

2001-02-01

Full Text Available Utilizando potros, avaliaram-se dietas em que a proteína do farelo de soja foi substituído em diferentes níveis (0; 35; 65 e 100% pela do farelo de canola. As rações foram isoprotéicas ( 17% PB e isocalóricas (4200 kcal/kg. Foram utilizados 16 eqüinos da raça Mangalarga, sendo oito machos e oito fêmeas, com média de dez meses e 218 kg PV inicial, consumindo um total de 2,5% PV, na matéria seca (MS. A dieta era composta por 40% de volumoso e 60% de concentrado. O delineamento experimental utilizado foi em blocos ao acaso, considerando quatro blocos e quatro tratamentos. Não se verificou efeito dos tratamentos sobre as variáveis de desempenho (ganho diário de peso vivo, altura na cernelha, perímetro torácico e perímetro da canela e parâmetros sangüíneos (glicose e uréia dos potros em crescimento. Nos concentrados para potros dos 9 a 11,5 meses de idade, o farelo de soja pode ser substituído pelo farelo de canola.Diets composed by four different levels (0; 53; 65 and 100% of canola meal replacing soybean meal crude protein (CP were evaluated using foals. The diets were isoproteic (17% CP and isocaloric (4200 kcal/kg. Sixteen Managalarga breed foals, eight males and eight females, averaging 10 months and 218 kg LW, fed a total intake of 2.5% LW on dry matter (DM basis were used. The diet was composed by 60:40 forage to concentrate ratio. A completely block experimental design, with four blocks and four treatments, was used. There were no effect of treatments on the performance variables (average daily gain, wither height, heart girth and cannon bone circumference and blood parameters (glucose and urea of growing foals. In the concentrate for growing foals from 9 to 11.5 months old, the soybean meal can be replaced by canola meal.

Grau de exposição a praguicidas organoclorados em moradores de aterro a céu aberto

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Eladio Santos Filho

2003-08-01

Full Text Available OBJETIVO: Estimar o grau de exposição interna aos praguicidas organoclorados (POP dos moradores de um atêrro a céu aberto. MÉTODOS: Estudo observacional, de aferição simultânea e controlado, cujo fator de estudo foi residir em área contaminada por POP e o efeito foi a concentração sanguínea dessas substâncias. A população de estudo foi de 238 pessoas residentes em um aterro a céu aberto (Pilões, no município de Cubatão, SP; e a população de controle ficou dimensionada em 258 pessoas, também residentes no mesmo município (Cota 200. Foram analisados os praguicidas HCB, p-p'DDT, p-p'DDE, p-p'DDD, o-p'DDT, a HCH; b HCH; g HCH; Aldrin; Dieldrin; Endrin; Heptaclor; Heptaclor-epoxi e Mirex. RESULTADOS: Os teores médios sangüíneos de HCB em Pilões foram de 4,66 µg/L, 155 vezes maior que a média na Cota 200 (0,03 µg/L. Em Pilões, os teores médios de DDT total foram de 3,71 µg/L, duas vezes maior do que na Cota 200 (1,85 µg/L e o HCH total apresentou concentrações sangüíneas seis vezes maiores em Pilões, 0,84 µg/L, contra 0,13 µg/L. CONCLUSÕES: Evidenciou-se associação positiva entre residir em Pilões e apresentar teores sangüíneos de POP, com risco muitas vezes maior quando comparado a localidades sem a presença desses contaminantes.

Grau de exposição a praguicidas organoclorados em moradores de aterro a céu aberto

Directory of Open Access Journals (Sweden)

Santos Filho Eladio

2003-01-01

Full Text Available OBJETIVO: Estimar o grau de exposição interna aos praguicidas organoclorados (POP dos moradores de um atêrro a céu aberto. MÉTODOS: Estudo observacional, de aferição simultânea e controlado, cujo fator de estudo foi residir em área contaminada por POP e o efeito foi a concentração sanguínea dessas substâncias. A população de estudo foi de 238 pessoas residentes em um aterro a céu aberto (Pilões, no município de Cubatão, SP; e a população de controle ficou dimensionada em 258 pessoas, também residentes no mesmo município (Cota 200. Foram analisados os praguicidas HCB, p-p'DDT, p-p'DDE, p-p'DDD, o-p'DDT, a HCH; b HCH; g HCH; Aldrin; Dieldrin; Endrin; Heptaclor; Heptaclor-epoxi e Mirex. RESULTADOS: Os teores médios sangüíneos de HCB em Pilões foram de 4,66 µg/L, 155 vezes maior que a média na Cota 200 (0,03 µg/L. Em Pilões, os teores médios de DDT total foram de 3,71 µg/L, duas vezes maior do que na Cota 200 (1,85 µg/L e o HCH total apresentou concentrações sangüíneas seis vezes maiores em Pilões, 0,84 µg/L, contra 0,13 µg/L. CONCLUSÕES: Evidenciou-se associação positiva entre residir em Pilões e apresentar teores sangüíneos de POP, com risco muitas vezes maior quando comparado a localidades sem a presença desses contaminantes.

Features of reproduction in laboratory-reared Aedes fluviatilis (Lutz, 1904 (Diptera: Culicidae

Directory of Open Access Journals (Sweden)

Rotraut A. G. B. Cônsoli

1983-03-01

Full Text Available Observations were made on 100 female Aedes fluviatilis (Lutz maintained individually from the first blood meal onwards and allowed one blood meal during each oviposition cycle, 5% dextrose solution been supplied throughout life. The average length of live was 49.9 ± 17.8 days; the logarithm of the mortality rate increased proportionately to physiological age. The insects took an average of 7.3 ± 3.2 blood meals and produced a mean of 7.9 ± 3.7 clutches of eggs. There was a progressive decrease, proportional to advancing physiological age, in the mean numbers of eggs laid in successive oviposition cycles, in the intervals between blood feeding oviposition, and in the numbers of larvae that hatched. Delayed oviposition, transient sterility and a total loss of fertility were also recorded.De 100 fêmeas de Aedese fluviatilis (Lutz, 1904 individualmente observadas foram obtidos 45.475 ovos em um total de 790 posturas. As médias de desovas produzidas e de repastos sangüíneos ingeridos por fêmea, foram respectivamente 7,9 ± 3,7 e 7,3 ± 3,2 e a longevidade média foi de 49,9 ± 17,8 dias. Em análise de regressão linear, foi observado um progressivo decréscimo das médias de ovos por postura, larvas eclodidas e número de dias entre repasto sangüíneo e postura, proporcional ao aumento da idade fisiológica. Foram ainda observadas ocorrências de ingestão de sangue durante o desenvolvimento dos ovos, recusa de alimentação sangüínea entre desovas sucessivas, retenção espontânea de ovos por períodos apreciáveis, esterilidade transitória e esgotamento de fecundidade.

Testosterone affects song modulation during simulated territorial intrusions in male black redstarts (Phoenicurus ochruros.

Directory of Open Access Journals (Sweden)

Beate Apfelbeck

Full Text Available Although it has been suggested that testosterone plays an important role in resource allocation for competitive behavior, details of the interplay between testosterone, territorial aggression and signal plasticity are largely unknown. Therefore, we investigated if testosterone acts specifically on signals that communicate the motivation or ability of individuals to engage in competitive situations in a natural context. We studied the black redstart, a territorial songbird species, during two different life-cycle stages, the early breeding phase in spring and the non-breeding phase in fall. Male territory holders were implanted with the androgen receptor blocker flutamide (Flut and the aromatase inhibitor letrozole (Let to inhibit the action of testosterone and its estrogenic metabolites. Controls received a placebo treatment. Three days after implantation birds were challenged with a simulated territorial intrusion (STI. Song was recorded before, during and after the challenge. In spring, both treatment groups increased the number of elements sung in parts of their song in response to the STI. However, Flut/Let-implanted males reacted to the STI with a decreased maximum acoustic frequency of one song part, while placebo-implanted males did not. Instead, placebo-implanted males sang the atonal part of their song with a broader frequency range. Furthermore, placebo-, but not Flut/Let-implanted males, sang shorter songs with shorter pauses between parts in the STIs. During simulated intrusions in fall, when testosterone levels are naturally low in this species, males of both treatment groups sang similar to Flut/Let-implanted males during breeding. The results suggest that song sung during a territorial encounter is of higher competitive value than song sung in an undisturbed situation and may, therefore, convey information about the motivation or quality of the territory holder. We conclude that testosterone facilitates context-dependent changes

Genetic of the ABO blood system and its link with the immune system A genética do sistema ABO e sua relação com o sistema imune

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Luiz C. de Mattos

2004-03-01

Full Text Available In the book "Eat Right For Your Type" the author Peter J. D'Adamo writes that the O blood type was the first blood type to appear in humans and affirms that the blood groups are the key to the immune system. Some recent phylogenetic network studies in humans and non-human primates implies that the A gene represents an ancient form of the ABO genes. Relationships between blood groups and infectious and noninfectious diseases and immunodeficiency abnormalities have also been reported in the literature. As D'Adamo's propositions seem to be in opposition with the current knowledge, we present in this paper some comments about the genetics and the evolution of the ABO blood group genes and some links between this blood system and the functioning of the immune system.Peter J. D'Adamo, autor do livro "Eat Right For Your Type", escreve que o grupo O representa o primeiro tipo sangüíneo que surgiu nos humanos e também afirma que os grupos sangüíneos constituem as bases do sistema imune. Recentes estudos filogenéticos realizados em primatas humanos e não humanos estabeleceram que o gene A representa a forma ancestral dos genes que ocupam o locus ABO. Associações entre os grupos sangüíneos ABO, doenças infecciosas, não infecciosas e imunodeficiências também foram relatadas. Diante das proposições do autor, as quais se opõem às informações resultantes de recentes estudos moleculares e filogenéticos, nossa intenção é apresentar algumas reflexões sobre a genética e a evolução dos genes do sistema ABO e as conexões deste sistema com o sistema imune.

Student Rights, Clarence Thomas, and the Revolutionary Vision of Education

Science.gov (United States)

Warnick, Bryan R.; Rowe, Bradley; Kim, Sang Hyun

2009-01-01

In his concurring opinion to the 2007 U.S. Supreme Court decision, "Morse v. Frederick," Justice Clarence Thomas argues that the "Tinker" decision, which granted students constitutional rights in public schools, should be overturned on originalist grounds. In this essay, Bryan Warnick, Bradley Rowe, and Sang Hyun Kim make the case that Thomas's…

Effects of a Preparatory Singing Pattern on Melodic Dictation Success

Science.gov (United States)

Buonviri, Nathan O.

2015-01-01

The purpose of this study was to investigate effects of a preparatory contextual singing pattern on melodic dictation test scores. Forty-nine undergraduate music education majors took melodic dictations under three conditions. After hearing an orienting chord sequence, they (1) sang a preparatory solfége pattern in the key, meter, and tempo of the…

Fun City

DEFF Research Database (Denmark)

Once the blues guitarist B.B. King sang that when he "didn't wanna live no more", he would go shopping instead. Now, however, shopping has become a lifestyle... The city of today has become "Disneyfied" and "Tivolized". It has become a scene for events. The aim of the book is to encircle and pin ...

FUN CITY

DEFF Research Database (Denmark)

Once the blues guitarist B.B. King sang that when he "didn't wanna live no more", he would go shopping instead. Now, however, shopping has become a lifestyle... The city of today has become "Disneyfied" and "Tivolized". It has become a scene for events. The aim of the book is to encircle and pin ...

Author Details

African Journals Online (AJOL)

Valeurs de reference de la creatinine serique chez les donneurs de sang au Centre National De Transfusion Sanguine (CNTS) de Lome (Togo) Abstract · Vol 16, No 2 (2014) - Articles Profil de l'hemogramme au cours de l'acces palustre simple a Plasmodium falciparum chez les enfants de 6 mois a 5 ans au Togo.

Une étude de cas. Saint Sébastien dans “Je suis sang” de Jan Fabre

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Lydie Toran

2017-06-01

Full Text Available Jan Fabre’s writing frequently displays a variety of quotations, especially visual ones. His 2001 Je suis sang (conte de fées médiéval is directly and indirectly inspired by Saint Sebastian’s iconography. This study examines the modalities and functions of this re-use in detail.

Current Knowledge on Microarray Technology - An Overview

African Journals Online (AJOL)

Erah

Review Article. Current Knowledge ... containing libraries of oligonucleotides robotically ... measurements, and averages over each oligonucleotide. ... quality of chips produced depends critically ..... Bae EK, Lee H, Lee JS, Noh EW. Isolation ...

Interferência dos ácidos graxos ômega-3 nos lipídeos sangüíneos de ratos submetidos ao exercício de natação Omega-3 fatty acids interference on the blood lipids of rats subjected to swimming exercise

Directory of Open Access Journals (Sweden)

Bettina Moritz

2008-12-01

Full Text Available OBJETIVO: Investigar os efeitos da suplementação com ácidos graxos ômega-3, nas doses de 0,5 e 1,0g/kg/dia, nos lipídeos sangüíneos de ratos submetidos ou não ao protocolo do nado. MÉTODOS: Ratos Wistar foram divididos em grupos: controle, controle+nado, ácidos graxos ômega-3 e ácidos graxos ômega-3+nado. Os ácidos graxos ômega-3 e ácidos graxos ômega-3+nado receberam suplementação; os demais receberam água por gavagem. Os controle+nado e ácidos graxos ômega-3+nado foram submetidos ao exercício. Foram avaliadas as concentrações plasmáticas de colesterol total, triglicérides e lipoproteína de alta densidade, antes e após os procedimentos experimentais. RESULTADOS: No protocolo de 0,5g/kg/dia, em relação às concentrações de colesterol total, foi observada redução significativa proporcionalmente maior no grupo ácidos graxos ômega-3+nado, apesar de o grupo controle+nado e o ácidos graxos ômega-3 também terem apresentado diminuição. No ensaio de 1,0g/kg/dia todos os grupos apresentaram uma diminuição que foi maior, respectivamente, no ácidos graxos ômega-3+nado e, a seguir, no ácidos graxos ômega-3. Quanto aos triglicérides, foram encontradas reduções em todos os grupos experimentais, que foi maior no grupo ácidos graxos ômega-3+nado, do protocolo de 0,5g/kg/dia, enquanto que no de 1,0g/kg/dia a diminuição foi significativa apenas nos grupos ácidos graxos ômega-3 e ácidos graxos ômega-3+nado. Quanto ao HDL, no protocolo de 0,5g/kg/dia foi encontrado aumento nos animais que não foram suplementados, enquanto que em todos os grupos de 1,0g/kg/dia houve uma diminuição do HDL. CONCLUSÃO: A suplementação com ácidos graxos ômega-3 nas doses 0,5 ou 1,0g/kg/dia, associada ao nado, reduzem as concentrações plasmáticas de colesterol total e triglcérides, mas estudos adicionais, também com outras doses, são necessários para a compreensão da relação entre a ingestão de óleo de peixe e

Contamination Assessment of Dumpsites in Ughelli, Nigeria using ...

African Journals Online (AJOL)

ADOWIE PERE

the cheap when compared to incineration method. (Mohammad ... Poor management of municipal solid waste in. Nigeria ... unprecedented environmental, bionomical and human ... water bodies and aquifer system(Lee and Jones-Lee,. 2004) ...

Crème de la crème / Joel Sang

Index Scriptorium Estoniae

Sang, Joel, 1950-

2011-01-01

Auhinnažürii esimees iseloomustab Eesti Kultuurkapitali kirjandusauhindade laureaate: Indrek Koff (luule), Maarja Kangro (proosa), Urmas Vadi (näitekirjandus), Toomas Haug (esseistika), Lauri Sommer (vabaauhind), Amar Annus (ilukirjanduslik tõlge võõrkeelest eesti keelde), Ilmar Lehtpere (ilukirjanduslik tõlge eesti keelest võõrkeelde), Kristiina Kass (lastekirjandus), Sergei Issakov (venekeelse autori kirjandusauhind) ja Mart Velsker (artikliauhind)

Mata Ketiga: Se Laen, Sang Pembebas Sistem Pendidikan Tinggi Akuntansi

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Iwan Triyuwono

2010-04-01

Full Text Available The objectives of the study are to criticize the existing accounting education especially in Indonesian universities and to give an alternative idea for a better one. It is done as there is a strong indication that accounting education is driven by intellectual intelligence, market, and other artificial interests. Through a deconstruction approach and critical analysis, the study suggests the internalization of “Mata Ketiga” (the Third Eye in accounting curriculum. Mata Ketiga, that refers to spiritual intelligence, is “the Other” that is consciously entered to the singularity of intellectual intelligence of modern curriculum. Under the internalization of Mata Ketiga, accounting education can be emancipated from the domination of intellectual intelligence, market, and other artificial interests. By doing so, the education may guide an accounting student to find his/her “real self” without neglecting contemporary accounting competence.

Prevalence des hemolysines chez les donneurs de sang de groupe ...

African Journals Online (AJOL)

Objectifs : Déterminer la fréquence et le titre des hémolysines anti-A et anti-B dans la population des donneurs O et de prédire de l'intérêt de la systématisation de leur recherche chez tous les donneurs O par l'évaluation du risque d'accident transfusionnels liés aux hémolysines. Méthodologie : Etude prospective au ...

Simulation for light extraction efficiency of OLEDs with spheroidal microlenses in hexagonal array

Science.gov (United States)

Bae, Hyungchul; Kim, Jun Soo; Hong, Chinsoo

2018-05-01

A theoretical model based on ray optics is used to simulate the optical performance of organic light-emitting diodes (OLEDs) with spheroidal microlens arrays (MLAs) in a hexagonal array configuration using the Monte Carlo method. In simulations, ray tracing was performed until 20 reflections occurred from the metal cathode, with 10 consecutive reflections permitted in a single lens pattern. The parameters describing the shape and array of the lens pattern of a MLA are its radius, height, contact angle, and fill factor (FF). Many previous results on how these parameters affect light extraction efficiency (LEE) are inconsistent. In this paper, these contradictory results are discussed and explained by introducing a new parameter. To examine light extraction from an OLED through a MLA, the LEE enhancement is studied considering the effect of absorption by indium tin oxide during multiple reflections from the metal cathode. The device size where LEE enhancement is unchanged with changing lens pattern was identified for a fixed FF; under this condition, the optimal LEE enhancement, 84%, can be obtained using an OLED with a close-packed spheroidal MLA. An ideal maximum LEE enhancement of 120% was achieved with a device with an infinite-sized MLA. The angular intensity distribution of light emitted through a MLA is considered in addition to LEE enhancement for an optimized MLA.

Benchmarking quantum mechanical calculations with experimental NMR chemical shifts of 2-HADNT

Science.gov (United States)

Liu, Yuemin; Junk, Thomas; Liu, Yucheng; Tzeng, Nianfeng; Perkins, Richard

2015-04-01

In this study, both GIAO-DFT and GIAO-MP2 calculations of nuclear magnetic resonance (NMR) spectra were benchmarked with experimental chemical shifts. The experimental chemical shifts were determined experimentally for carbon-13 (C-13) of seven carbon atoms for the TNT degradation product 2-hydroxylamino-4,6-dinitrotoluene (2-HADNT). Quantum mechanics GIAO calculations were implemented using Becke-3-Lee-Yang-Parr (B3LYP) and other six hybrid DFT methods (Becke-1-Lee-Yang-Parr (B1LYP), Becke-half-and-half-Lee-Yang-Parr (BH and HLYP), Cohen-Handy-3-Lee-Yang-Parr (O3LYP), Coulomb-attenuating-B3LYP (CAM-B3LYP), modified-Perdew-Wang-91-Lee-Yang-Parr (mPW1LYP), and Xu-3-Lee-Yang-Parr (X3LYP)) which use the same correlation functional LYP. Calculation results showed that the GIAO-MP2 method gives the most accurate chemical shift values, and O3LYP method provides the best prediction of chemical shifts among the B3LYP and other five DFT methods. Three types of atomic partial charges, Mulliken (MK), electrostatic potential (ESP), and natural bond orbital (NBO), were also calculated using MP2/aug-cc-pVDZ method. A reasonable correlation was discovered between NBO partial charges and experimental chemical shifts of carbon-13 (C-13).

Plaadid / Immo Mihkelson

Index Scriptorium Estoniae

Mihkelson, Immo, 1959-

2004-01-01

Uutest plaatidest Ragatmika "Katkiminekud", "Killing Joke", The Streets "A Grand Don't Come For Free", Jamie Cullum "Twentysomething", Armand Van Helden "New York: A Mix Odyssey", Awan Lee "Swan Lee 2nd album"

Staaride oma reality'd / Jaanus Noormets

Index Scriptorium Estoniae

Noormets, Jaanus

2005-01-01

Isiklikud tõsielusarjad televisioonis saavad sel suvel teiste seas endale ka poplaulja Britny Spears ("Britney and Kevin: Chaotic") ja rokkarid Bobby Brown ("Being Bobby Brown") ning Tommy Lee ("Tommy Lee Goes to Collage")

Leninskaja pravda. Iz vseh iskusstv dlja nas vazhneishim javljajetsja kino / Ilja Sundelevitsh

Index Scriptorium Estoniae

Sundelevitsh, Ilja

2001-01-01

Kunstinäitustest Tallinnas: Tallinna XII graafikatriennaali näitused Rotermanni soolalaos (peanäitus), Kunstihoones (Johannes Saare kuraatorinäitus), Hansapanga galeriis (noortenäitus), Linnagaleriis (eelmise graafikatriennaali võitja Sang-Gon Chungi tööd), Adamson-Ericu muuseumis (eelmiste triennaalide võitjad) jm. Noorte metallikunstnike Andrus Rummu ja Kaarel Sireli töödest A-galeriis.

Etiologie particuliere de l'encephalite limbique : la neurosyphilis (a ...

African Journals Online (AJOL)

... temporo-limbiques, la sérologie de la syphilis fut positive dans le sang et le LCR. Le diagnostic d'encéphalite limbique syphilitique fut retenu sur un ensemble d'arguments clinique, biologique et radiologique. Le traitement spécifique de la neurosyphilis a permis une amélioration de l'état neurologique des deux patients.

Polymerase Chain Reaction To Determine Frequency Of ...

African Journals Online (AJOL)

PCR amplification of the DHFR-TS could be used to determine frequency of pyrimethamine resistant P. falciparum strains in malaria blood. Plasmodium falciparum résistant dans ... Les mutations étaient identifiées directement dans les prélèvement de sang obtenus de malades qui visitent les hôpitaux pour les services de ...

number 3

African Journals Online (AJOL)

Val

dant certaines précautions (prélèvement aseptique du sang [1], décantage et filtrage) pour éviter en particu- lier des accidents dus aux micro-caillots en suspen- .... Structure, blood supply, and lymphatic vessels the sheep's visceral pleura. Am J Anat 1982; 165 : 277-94. 3. Committee on Trauma American College of.

Playback and Feedback: Revelations of an "Encoding, Decoding" Analysis of Popular Songs Used to Teach English in China

Science.gov (United States)

Goering, Christian Z.; Wei, Huang

2014-01-01

In 2009 Rupke and Blank noted that the Chinese students in their study sang American songs that the researchers had never heard. This perceived dissonance could have a multitude of causes, but the authors of this article turned their attention to the curriculum used for teaching English in China to further understand the popularity and persistence…