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Sample records for rosuvastatin astronomer study

  1. Photocatalytic degradation of rosuvastatin: Analytical studies and toxicity evaluations

    Energy Technology Data Exchange (ETDEWEB)

    Machado, Tiele Caprioli, E-mail: tiele@enq.ufrgs.br [Chemical Engineering Department, Federal University of Rio Grande do Sul, Rua Engenheiro Luiz Englert s/n, CEP: 90040-040 Porto Alegre, RS (Brazil); Pizzolato, Tânia Mara [Chemical Institute, Federal University of Rio Grande do Sul, Avenida Bento Gonçalves, 9500, CEP: 91501-970 Porto Alegre, RS (Brazil); Arenzon, Alexandre [Ecology Center, Federal University of Rio Grande do Sul, Avenida Bento Gonçalves, 9500, CEP: 91501-970 Porto Alegre, RS (Brazil); Segalin, Jeferson [Biotechnology Center, Federal University of Rio Grande do Sul, Avenida Bento Gonçalves, 9500, CEP: 91501-970 Porto Alegre, RS (Brazil); Lansarin, Marla Azário [Chemical Engineering Department, Federal University of Rio Grande do Sul, Rua Engenheiro Luiz Englert s/n, CEP: 90040-040 Porto Alegre, RS (Brazil)

    2015-01-01

    Photocatalytic degradation of rosuvastatin, which is a drug that has been used to reduce blood cholesterol levels, was studied in this work employing ZnO as catalyst. The experiments were carried out in a temperature-controlled batch reactor that was irradiated with UV light. Preliminary the effects of the photocatalyst loading, the initial pH and the initial rosuvastatin concentration were evaluated. The experimental results showed that rosuvastatin degradation is primarily a photocatalytic process, with pseudo-first order kinetics. The byproducts that were generated during the oxidative process were identified using nano-ultra performance liquid chromatography tandem mass spectrometry (nano-UPLC–MS/MS) and acute toxicity tests using Daphnia magna were done to evaluate the toxicity of the untreated rosuvastatin solution and the reactor effluent. - Highlights: • The photocatalytic degradation of rosuvastatin was studied under UV irradiation. • Commercial catalyst ZnO was used. • Initial rosuvastatin concentration, photocatalyst loading and pH were evaluated. • The byproducts generated during the oxidative process were detected and identified. • Acute toxicity tests using Daphnia magna were carried out.

  2. Effect of fixed-dose combinations of ezetimibe plus rosuvastatin in patients with primary hypercholesterolemia: MRS-ROZE (Multicenter Randomized Study of ROsuvastatin and eZEtimibe).

    Science.gov (United States)

    Kim, Kyung-Jin; Kim, Sang-Hyun; Yoon, Young Won; Rha, Seung-Woon; Hong, Soon-Jun; Kwak, Choong-Hwan; Kim, Weon; Nam, Chang-Wook; Rhee, Moo-Yong; Park, Tae-Ho; Hong, Taek-Jong; Park, Sungha; Ahn, Youngkeun; Lee, Namho; Jeon, Hui-Kyung; Jeon, Dong-Woon; Han, Kyoo-Rok; Moon, Keon-Woong; Chae, In-Ho; Kim, Hyo-Soo

    2016-10-01

    We aimed to compare the effects of fixed-dose combinations of ezetimibe plus rosuvastatin to rosuvastatin alone in patients with primary hypercholesterolemia, including a subgroup analysis of patients with diabetes mellitus (DM) or metabolic syndrome (MetS). This multicenter eight-week randomized double-blind phase III study evaluated the safety and efficacy of fixed-dose combinations of ezetimibe 10 mg plus rosuvastatin, compared with rosuvastatin alone in patients with primary hypercholesterolemia. Four hundred and seven patients with primary hypercholesterolemia who required lipid-lowering treatment according to the ATP III guideline were randomized to one of the following six treatments for 8 weeks: fixed-dose combinations with ezetimibe 10 mg daily plus rosuvastatin (5, 10, or 20 mg daily) or rosuvastatin alone (5, 10, or 20 mg daily). Fixed-dose combination of ezetimibe plus rosuvastatin significantly reduced LDL cholesterol, total cholesterol, and triglyceride levels compared with rosuvastatin alone. Depending on the rosuvastatin dose, these fixed-dose combinations of ezetimibe plus rosuvastatin provided LDL cholesterol, total cholesterol, and triglyceride reductions of 56%-63%, 37%-43%, and 19%-24%, respectively. Moreover, the effect of combination treatment on cholesterol levels was more pronounced in patients with DM or MetS than in non-DM or non-MetS patients, respectively, whereas the effect of rosuvastatin alone did not differ between DM vs non-DM or MetS vs non-MetS patients. Fixed-dose combinations of ezetimibe and rosuvastatin provided significantly superior efficacy to rosuvastatin alone in lowering LDL cholesterol, total cholesterol, and triglyceride levels. Moreover, the reduction rate was greater in patients with DM or MetS. © 2016 The Authors Cardiovascular Therapeutics Published by John Wiley & Sons Ltd.

  3. Rosuvastatin safety: An experimental study of myotoxic effects and mitochondrial alterations in rats.

    Science.gov (United States)

    El-Ganainy, Samar O; El-Mallah, Ahmed; Abdallah, Dina; Khattab, Mahmoud M; Mohy El-Din, Mahmoud M; El-Khatib, Aiman S

    2017-01-04

    Myopathy is the most commonly reported adverse effect of statins. All statins are associated with myopathy, though with different rates. Rosuvastatin is a potent statin reported to induce myopathy comparable to earlier statins. However, in clinical practice most patients could tolerate rosuvastatin over other statins. This study aimed to evaluate the myopathic pattern of rosuvastatin in rats using biochemical, functional and histopathological examinations. The possible deleterious effects of rosuvastatin on muscle mitochondria were also examined. The obtained results were compared to myopathy induced by atorvastatin in equimolar dose. Results showed that rosuvastatin induced a rise in CK, a slight increase in myoglobin level together with mild muscle necrosis. Motor activity, assessed by rotarod, showed that rosuvastatin decreased rats' performance. All these manifestations were obviously mild compared to the prominent effects of atorvastatin. Parallel results were obtained in mitochondrial dysfunction parameters. Rosuvastatin only induced a slight increase in LDH and a minor decrease in ATP (∼14%) and pAkt (∼12%). On the other hand, atorvastatin induced an increase in LDH, lactate/pyruvate ratio and a pronounced decline in ATP (∼80%) and pAkt (∼65%). These findings showed that rosuvastatin was associated with mild myotoxic effects in rats, especially when compared to atorvastatin. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  4. Comparison of rosuvastatin and atorvastatin for lipid lowering in patients with type 2 diabetes mellitus: results from the URANUS study

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    Berne Christian

    2005-06-01

    Full Text Available Abstract Objective The Use of Rosuvastatin versus Atorvastatin iN type 2 diabetes mellitUS (URANUS study compared rosuvastatin with atorvastatin for the reduction of low-density lipoprotein cholesterol (LDL-C in patients with type 2 diabetes. Methods After a 6-week dietary run-in, patients aged ≥ 18 years with type 2 diabetes and LDL-C ≥ 3.3 mmol/L were randomised to double-blind treatment with rosuvastatin 10 mg (n = 232 or atorvastatin 10 mg (n = 233 for 4 weeks. Doses were then titrated up to a maximum of rosuvastatin 40 mg or atorvastatin 80 mg over 12 weeks to achieve the 1998 European LDL-C goal ( Results Rosuvastatin reduced LDL-C levels significantly more than atorvastatin during the fixed-dose and titration periods (p Conclusion At the start dose and following dose titration, rosuvastatin was significantly more effective than atorvastatin at reducing LDL-C and achieving European LDL-C goals in patients with type 2 diabetes.

  5. Rosuvastatin-Induced Carotid Plaque Regression in Patients With Inflammatory Joint Diseases: The Rosuvastatin in Rheumatoid Arthritis, Ankylosing Spondylitis and Other Inflammatory Joint Diseases Study.

    Science.gov (United States)

    Rollefstad, S; Ikdahl, E; Hisdal, J; Olsen, I C; Holme, I; Hammer, H B; Smerud, K T; Kitas, G D; Pedersen, T R; Kvien, T K; Semb, A G

    2015-07-01

    Patients with rheumatoid arthritis (RA) and carotid artery plaques have an increased risk of acute coronary syndromes. Statin treatment with the goal of achieving a low-density lipoprotein (LDL) cholesterol level of ≤1.8 mmoles/liter (≤70 mg/dl) is recommended for individuals in the general population who have carotid plaques. The aim of the ROsuvastatin in Rheumatoid Arthritis, Ankylosing Spondylitis and other inflammatory joint diseases (RORA-AS) study was to evaluate the effect of 18 months of intensive lipid-lowering treatment with rosuvastatin with regard to change in carotid plaque height. Eighty-six patients (60.5% of whom were female) with carotid plaques and inflammatory joint disease (55 with RA, 21 with AS, and 10 with psoriatic arthritis) were treated with rosuvastatin to obtain the LDL cholesterol goal. Carotid plaque height was evaluated by B-mode ultrasonography. The mean ± SD age of the patients was 60.8 ± 8.5 years, and the median compliance with rosuvastatin treatment was 97.9% (interquartile range [IQR] 96.0-99.4). At baseline, the median number and height of the carotid plaques were 1.0 (range 1-8) and 1.80 mm (IQR 1.60-2.10), respectively. The mean ± SD change in carotid plaque height after 18 months of treatment with rosuvastatin was -0.19 ± 0.35 mm (P < 0.0001). The mean ± SD baseline LDL cholesterol level was 4.0 ± 0.9 mmoles/liter (154.7 ± 34.8 mg/dl), and the mean reduction in the LDL cholesterol level was -2.3 mmoles/liter (95% confidence interval [95% CI] -2.48, -2.15) (-88.9 mg/dl [95% CI -95.9, -83.1]). The mean ± SD LDL cholesterol level during the 18 months of rosuvastatin treatment was 1.7 ± 0.4 mmoles/liter (area under the curve). After adjustment for age/sex/blood pressure, no linear relationship between a reduction in carotid plaque height and the level of LDL cholesterol exposure during the study period was observed. Attainment of the LDL cholesterol goal of ≤1.8 mmoles/liter (≤70

  6. A comparative study of efficacy of atorvastatin, rosuvastatin, and atorvastatin + fibrates as lipid lowering agents

    OpenAIRE

    Karunasree Nagarur; Yamini Vadlamannati; Narasimha Rao Raja

    2016-01-01

    Background: Hypercholesterolemia patients are at high risk of coronary heart disease. National cholesterol education programme (NCEP) Adult Treatment Panel III guidelines provide the option of aggressively lowering Low-density cholesterol in them. Presently the standard therapy of hypercholesterolemia is by HMG co-A reductase inhibitors. Present study shows that Rosuvastatin is better than Atorvastatin, Atorvastatin and Fibrate is better than Atorvastatin monotherapy in management of hypercho...

  7. rosuvastatin (JUPITER)

    DEFF Research Database (Denmark)

    Ridker, Paul M; MacFadyen, Jean G; Fonseca, Francisco A H

    2009-01-01

    were calculated across a range of end points, timeframes, and subgroups using data from Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER), a randomized evaluation of rosuvastatin 20 mg versus placebo conducted among 17 802 apparently healthy men...... infarction, stroke, revascularization, or death, the 5-year NNT within JUPITER was 20 (95% CI, 14 to 34). All subgroups had 5-year NNT values for this end point below 50; as examples, 5-year NNT values were 17 for men and 31 for women, 21 for whites and 19 for nonwhites, 18 for those with body mass index 300...

  8. Comparison of the efficacy and safety of rosuvastatin 10 mg and atorvastatin 20 mg in high-risk patients with hypercholesterolemia – Prospective study to evaluate the Use of Low doses of the Statins Atorvastatin and Rosuvastatin (PULSAR

    Directory of Open Access Journals (Sweden)

    García Hugo

    2006-12-01

    Full Text Available Abstract Background Many patients at high risk of cardiovascular disease do not achieve recommended low-density lipoprotein cholesterol (LDL-C goals. This study compared the efficacy and safety of low doses of rosuvastatin (10 mg and atorvastatin (20 mg in high-risk patients with hypercholesterolemia. Methods A total of 996 patients with hypercholesterolemia (LDL-C ≥ 3.4 and Results Rosuvastatin 10 mg reduced LDL-C levels significantly more than atorvastatin 20 mg at week 6 (44.6% vs. 42.7%, p Conclusion In high-risk patients with hypercholesterolemia, rosuvastatin 10 mg was more efficacious than atorvastatin 20 mg at reducing LDL-C, enabling LDL-C goal achievement and improving other lipid parameters. Both treatments were well tolerated.

  9. Efficacy and safety of rosuvastatin therapy in children and adolescents with familial hypercholesterolemia: Results from the CHARON study

    NARCIS (Netherlands)

    Braamskamp, Marjet J. A. M.; Langslet, Gisle; McCrindle, Brian W.; Cassiman, David; Francis, Gordon A.; Gagné, Claude; Gaudet, Daniel; Morrison, Katherine M.; Wiegman, Albert; Turner, Traci; Kusters, D. Meeike; Miller, Elinor; Raichlen, Joel S.; Wissmar, Jenny; Martin, Paul D.; Stein, Evan A.; Kastelein, John J. P.

    2015-01-01

    Heterozygous familial hypercholesterolemia (HeFH) is an autosomal dominant disorder leading to premature atherosclerosis. Guidelines recommend initiating statins early to reduce low-density lipoprotein cholesterol (LDL-C). Studies have evaluated rosuvastatin in children aged ≥10 years, but its

  10. Why did high-dose rosuvastatin not improve cardiac remodeling in chronic heart failure? Mechanistic insights from the UNIVERSE study.

    Science.gov (United States)

    Ashton, Emma; Windebank, Emma; Skiba, Marina; Reid, Christopher; Schneider, Hans; Rosenfeldt, Franklin; Tonkin, Andrew; Krum, Henry

    2011-02-03

    Statins are often prescribed for prevention of atherosclerotic outcomes in patients who have chronic heart failure (CHF), if this has an ischaemic etiology. These agents may also possess additional properties, independent of effects on blood lipid levels, which may have an effect on cardiac remodeling. However, beneficial effects were not observed in the recent UNIVERSE trial. We prospectively planned a sub-study of UNIVERSE to explore relevant mechanistic effects of rosuvastatin, including effects on collagen turnover and plasma coenzyme Q10 (CoQ) levels. Additionally, CoQ levels in CHF patients receiving chronic statin therapy were measured. CoQ levels were significantly reduced after 26 weeks of rosuvastatin statin therapy (n = 32), compared to placebo (n = 37) in CHF patients in UNIVERSE trial. Patients with CHF (n = 56) matched for age, gender and severity of disease who had been taking statins for 12 months or longer had CoQ levels of 847 ± 344 nmol/L, significantly lower than 1065.4 ± 394 nmol/L in UNIVERSE patients at baseline (p = 0.0001). Serum types I and III N-terminal procollagen peptide (PINP and PIIINP), measures of collagen turnover which can contribute to cardiac fibrosis were significantly increased in the rosuvastatin group compared to baseline in UNIVERSE patients (PINP: p = 0.03, PIIINP: p = 0.001). In conclusion putative beneficial effects of statin therapy on cardiac remodeling in UNIVERSE may have been negated by increases in collagen turnover markers as well as a reduction in plasma CoQ levels in these patients with CHF. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  11. Pharmacokinetics of a telmisartan/rosuvastatin fixed-dose combination: a single-dose, randomized, open-label, 2-period crossover study in healthy Korean subjects.

    Science.gov (United States)

    Chae, Dong Woo; Son, Mijeong; Kim, Yukyung; Son, Hankil; Jang, Seong Bok; Seo, Jeong Min; Nam, Su Youn; Park, Kyungsoo

    2015-10-01

    As hypertension and dyslipidemia are frequent comorbidities, antihypertensive drugs and lipid-lowering agents are often prescribed together for their treatment. Telmisartan and rosuvastatin are widely used together to treat hypertension and dyslipidemia. A combination formulation of these two drugs would improve patient compliance due to ease of dosing. The purpose of this study was to assess bioequivalence of single-dose administration of a newly-developed fixed-dose combination (FDC) tablet containing telmisartan/rosuvastatin 80/20 mg (test treatment) and coadministration of a telmisartan 80-mg tablet and a rosuvastatin 20-mg tablet (reference treatment) in healthy Korean male volunteers. This was a single-dose, randomized, open-label, 2-period crossover study enrolling healthy males aged 20 - 50 years with BMI between 18.5 and 25 kg/m2. Each subject received a single dose of the reference and test treatments with a 14-day washout period. Blood sampling was performed at prespecified intervals for up to 72 hours after dosing. Primary pharmacokinetic parameters were Cmax, AUClast, and AUC0-∞ of telmisartan, rosuvastatin, and N-desmethyl rosuvastatin. Bioequivalence was assessed by determining whether the 90% confidence intervals (CIs) of the geometric mean ratios (test treatment/reference treatment) of these parameters were within the standard range of 80% to 125%. Adverse events were monitored via regular interviews with the subjects and by physical examinations. 60 subjects were enrolled and 55 completed the study. The 90% CIs of the geometric mean ratios of Cmax, AUClast, and AUC00-∞ were 0.9262-1.1498, 0.9294-1.0313, and 0.9312-1.0320 for telmisartan, 0.9041-1.0428, 0.9262-1.0085, and 0.9307-1.0094 for rosuvastatin, and 0.8718-1.0022, 0.8901-0.9904, and 0.8872-0.9767 for N-desmethyl rosuvastatin, respectively. There was no statistical difference in the incidence of adverse events (AEs) (all of which were mild or moderate) between the reference and test

  12. Rosuvastatin-induced pemphigoid.

    LENUS (Irish Health Repository)

    Murad, Aizuri A

    2012-01-01

    Statins are widely prescribed medications and very well tolerated. Rosuvastatin is another member of this drug used to treat dyslipidaemia. It is a competitive inhibitor of the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase. Immunobullous disease is usually idiopathic but can be drug-induced. Both idiopathic and iatrogenic forms share common clinical and immunohistological features. The authors report a case of pemphigoid induced by rosuvastatin, a commonly prescribed medication. To our knowledge, there is limited report on rosuvastatin associated with pemphigoid in the literature.

  13. Astronomical Plate Archives and Binary Blazars Studies

    Czech Academy of Sciences Publication Activity Database

    Hudec, René

    2011-01-01

    Roč. 32, 1-2 (2011), s. 91-95 ISSN 0250-6335. [Conference on Multiwavelength Variability of Blazars. Guangzhou, 22,09,2010-24,09,2010] R&D Projects: GA ČR GA205/08/1207 Grant - others:GA ČR(CZ) GA102/09/0997; MŠMT(CZ) ME09027 Institutional research plan: CEZ:AV0Z10030501 Keywords : astronomical plates * plate archives archives * binary blazars Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 0.400, year: 2011

  14. Effect of Steady-State Faldaprevir on Pharmacokinetics of Atorvastatin or Rosuvastatin in Healthy Volunteers: A Prospective Open-Label, Fixed-Sequence Crossover Study.

    Science.gov (United States)

    Huang, Fenglei; Marzin, Kristell; Koenen, Rüdiger; Kammerer, Klaus Peter; Strelkowa, Natalja; Elgadi, Mabrouk; Quinson, Anne-Marie; Haertter, Sebastian

    2017-10-01

    Faldaprevir (FDV) is a potent, orally administered inhibitor of hepatitis C virus protease. It inhibits multiple cytochrome P-450 enzymes and multiple membrane transporters. The objective of this study was to evaluate the effect of steady-state faldaprevir on the pharmacokinetics (PK) of a single dose of atorvastatin or rosuvastatin. In this single-center, open-label, fixed-sequence crossover study, 33 healthy adult male and female volunteers were given either atorvastatin 10 mg (n = 16) or rosuvastatin 10 mg (n = 17) on day 1. Subjects subsequently received 240 mg twice daily of faldaprevir (loading dose) on day 5, followed by 240 mg faldaprevir once daily from day 6 to day 10, with an additional single dose of atorvastatin (10 mg) or rosuvastatin (10 mg) given on day 10. PK samples for the statins were collected on days 1-3 and days 10-12. Concomitant administration with faldaprevir led to approximately 9-fold and 34-fold increases in AUC 0-∞ and C max , respectively, of atorvastatin and approximately 15-fold and 33-fold increases in AUC 0-∞ and C max , respectively, of rosuvastatin, compared with the statins given alone. Exposure to the major metabolites (ortho-hydroxyatorvastatin and N-desmethylrosuvastatin) was increased to a similar magnitude as that of the parent compounds. The marked drug-drug interaction observed is most likely related to the inhibitory effects of faldaprevir on transporters, particularly hepatic uptake transporters such as OTAP1B1 and OATP1B3. Given the significant increase in exposure to statins in healthy volunteers, coadministration of faldaprevir with statins should be avoided. © 2017, The American College of Clinical Pharmacology.

  15. A pharmacokinetic and pharmacodynamic drug interaction between rosuvastatin and valsartan in healthy subjects.

    Science.gov (United States)

    Jung, Jin Ah; Lee, Soo-Yun; Kim, Jung-Ryul; Ko, Jae-Wook; Jang, Seong Bok; Nam, Su Youn; Huh, Wooseong

    2015-01-01

    Valsartan, an angiotensin-receptor blocker, and rosuvastatin, a competitive inhibitor of the 3-hydroxy-3-methylglutaryl coenzyme A reductase, are frequently coadministered to treat patients with hypertension and dyslipidemia. The study reported here sought to evaluate the pharmacokinetic and pharmacodynamic interactions between rosuvastatin and valsartan in healthy Korean subjects. Thirty healthy male Korean subjects were administered with rosuvastatin (20 mg/day), valsartan (160 mg/day), and both drugs concomitantly for 4 days in a randomized, open-label, multiple-dose, three-treatment, three-period crossover study. Plasma concentrations of rosuvastatin, N-desmethyl rosuvastatin, and valsartan were determined using validated high-performance liquid chromatography with tandem mass spectrometry. Lipid profiles and vital signs (systolic and diastolic blood pressure and pulse rate) were measured for the pharmacodynamic assessment. For rosuvastatin, the geometric mean ratios (90% confidence intervals [CIs]) of coadministration to mono-administration were 0.8809 (0.7873-0.9857) for maximum plasma concentration at steady state and 0.9151 (0.8632-0.9701) for area under the concentration-time curve (AUC) over a dosing interval at steady state. For valsartan, the geometric mean ratios (90% CIs) of those were 0.9300 (0.7946-1.0884) and 1.0072 (0.8893-1.1406), respectively. There were no significant differences in the metabolic ratio of N-desmethyl rosuvastatin AUC to rosuvastatin AUC between coadministration and rosuvastatin alone. No interaction was found in terms of systolic or diastolic blood pressure or lipid profiles. Combined treatment with valsartan and rosuvastatin was generally well tolerated without serious adverse events. The pharmacokinetic profiles of rosuvastatin and valsartan in combination were comparable with those of rosuvastatin and valsartan administered individually, suggesting that their individual pharmacokinetics were not affected by their

  16. Antinociception induced by rosuvastatin in murine neuropathic pain.

    Science.gov (United States)

    Miranda, Hugo F; Sierralta, Fernando; Aranda, Nicolas; Poblete, Paula; Castillo, Rodrigo L; Noriega, Viviana; Prieto, Juan Carlos

    2018-06-01

    Neuropathic pain, and subsequent hypernociception, can be induced in mice by paclitaxel (PTX) administration and partial sciatic nerve ligation (PSNL). Its pharmacotherapy has been a clinical challenge, due to a lack of effective treatment. In two models of mouse neuropathic pain (PTX and PSNL) the antinociception induced by rosuvastatin and the participation of proinflammatory biomarkers, interleukin (IL)- 1β, TBARS and glutathione were evaluated. A dose-response curve for rosuvastatin ip was obtained on cold plate, hot plate and Von Frey assays. Changes on spinal cord levels of IL-1β, glutathione and lipid peroxidation were measured at 7 and 14days in PTX and PSNL murine models. PTX or PSNL were able to induce in mice peripheral neuropathy with hypernociception, either to 7 and 14days. Rosuvastatin induced a dose dependent antinociception in hot plate, cold plate and Von Frey assays. The increased levels of IL-1β or TBARS induced by pretreatment with PTX or PSNL were reduced by rosuvastatin. The reduction of spinal cord glutathione, by PTX or PSNL, expressed as the ratio GSH/GSSG, were increased significantly in animals pretreated with rosuvastatin. The anti-inflammatory properties of statins could underlie their beneficial effects on neuropathic pain by reduction of proinflammatory biomarkers and activation of glia. The findings of this study suggest a potential usefulness of rosuvastatin in the treatment of neuropathic pain. Copyright © 2018 Institute of Pharmacology, Polish Academy of Sciences. Published by Elsevier B.V. All rights reserved.

  17. Genotoxicity evaluation of HMG CoA reductase inhibitor rosuvastatin.

    Science.gov (United States)

    Berber, Ahmet Ali; Celik, Mustafa; Aksoy, Hüseyin

    2014-07-01

    The genotoxic potential of rosuvastatin as one of the statin drugs was assessed by chromosomal aberrations (CAs), micronucleus (MN) and DNA damage by comet assay in the human peripheral blood lymphocytes. Rosuvastatin was used at concentrations of 0.0625, 0.125, 0.25, 0.5 and 1 µg/mL for these in vitro assays. In all assays, a negative and positive control were also included. CA frequencies were significantly increased in all concentrations at 24 hours and significantly increased in all concentrations except 0.0625 µg/mL at 48 hours, compared to the negative control. Rosuvastatin has a decreased mitotic index (MI) at 0.5- and 1-µg/mL concentrations at 24 hours and at 0.25, 0.5 and 1 µg/mL at 48 hours. A significant increase was observed for induction of MN in all treatments, compared to the negative control. Cytokinesis-block proliferation indices were not affected by treatments with rosuvastatin. In the comet assay, significant increases in comet tail length and tail moment were observed at 0.0625-, 0.5- and 1-µg/mL concentrations. Comet intensity was significantly increased in all concentrations except 0.0625 µg/mL. According to these results, rosuvastatin is cytotoxic and clastogenic/aneugenic in human peripheral lymphocytes. Further studies should be conducted in other test systems to evaluate the full genotoxic potential of rosuvastatin.

  18. Evidence for a pharmacokinetic interaction between eslicarbazepine and rosuvastatin: Potential effects on xenobiotic transporters.

    Science.gov (United States)

    Gidal, Barry E; Mintzer, Scott; Schwab, Matthias; Schutz, Ralph; Kharidia, Jahnavi; Blum, David; Grinnell, Todd; Sunkaraneni, Soujanya

    2017-09-01

    Patients with partial-onset seizures and comorbid cardiovascular disease may concomitantly receive eslicarbazepine acetate (ESL), an antiepileptic drug, and rosuvastatin, an HMG-CoA reductase inhibitor. This study evaluated the effect of multiple-dose ESL on the pharmacokinetic (PK) parameters of a single dose of rosuvastatin in healthy subjects. This was a Phase I, single-center, fixed-sequence, open-label study. Healthy subjects received two treatments, in sequence. Treatment A: a single 40mg oral dose of rosuvastatin on Day 1, followed by a washout period (Days 1-4); treatment B: titration of ESL (400-800mg once daily) on Days 5-18, followed by ESL 1200mg once daily on Days 19-35, with a single dose of rosuvastatin (40mg) on Day 32. Subjects then entered a 2-week follow-up period. Plasma concentrations of rosuvastatin were quantified for PK analyses. Safety and tolerability were assessed throughout the study. Thirty-three healthy subjects were enrolled and 30 completed the study. Mean rosuvastatin (standard deviation) t 1/2 was similar when rosuvastatin was used concomitantly with ESL and when it was used alone (26.5 [16.3]h, and 22.4 [9.5]h, respectively). The geometric least squares mean ratios (90% confidence intervals) of rosuvastatin exposure levels between rosuvastatin used concomitantly with ESL and rosuvastatin used alone were as follows: C max , 64.0% (55.9-73.3%); AUC (0-∞) , 63.0% (57.1-69.4%); and AUC (0-last) , 60.9% (55.2-67.1%). Concomitant use of ESL and rosuvastatin was generally well tolerated. Rosuvastatin exposure was 36-39% lower with steady-state administration of ESL, potentially due to reduced oral bioavailability of rosuvastatin. Consequently, when rosuvastatin is used with ESL, a rosuvastatin dose adjustment may be necessary if a clinically significant change in lipids is noted. Copyright © 2017. Published by Elsevier B.V.

  19. Sustained Improvement of Arterial Stiffness and Blood Pressure after Long-Term Rosuvastatin Treatment in Patients with Inflammatory Joint Diseases: Results from the RORA-AS Study.

    Directory of Open Access Journals (Sweden)

    Eirik Ikdahl

    Full Text Available Patients with inflammatory joint diseases (IJD have a high prevalence of hypertension and increased arterial stiffness. The aim of the present study was to evaluate the effect of long-term rosuvastatin treatment on arterial stiffness, measured by augmentation index (AIx and aortic pulse wave velocity (aPWV, and blood pressure (BP in IJD patients with established atherosclerosis.Eighty-nine statin naïve IJD patients with carotid atherosclerotic plaque(s (rheumatoid arthritis n = 55, ankylosing spondylitis n = 23, psoriatic arthritis n = 11 received rosuvastatin for 18 months to achieve low-density lipoprotein cholesterol goal ≤1.8 mmol/L. Change in AIx (ΔAIx, aPWV (ΔaPWV, systolic BP (ΔsBP and diastolic BP (ΔdBP from baseline to study end was assessed by paired samples t-tests. Linear regression was applied to evaluate associations between cardiovascular disease (CVD risk factors, rheumatic disease specific variables and medication, and ΔAIx, ΔaPWV, ΔsBP and ΔdBP.AIx, aPWV, sBP and dBP were significantly reduced from baseline to study end. The mean (95%CI changes were: ΔAIx: -0.34 (-0.03, -0.65% (p = 0.03, ΔaPWV: -1.69 (-0.21, -3.17 m/s2 (p = 0.03, ΔsBP: -5.27 (-1.61, -8.93 mmHg (p = 0.004 and ΔdBP -2.93 (-0.86, -5.00 mmHg (p = 0.01. In linear regression models, ∆aPWV was significantly correlated with ΔsBP and ΔdBP (for all: p<0.001.There is an unmet need of studies evaluating CVD prevention in IJD patients. We have shown for the first time that long-term intensive lipid lowering with rosuvastatin improved arterial stiffness and induced a clinically significant BP reduction in patients with IJD. These improvements were linearly correlated and may represent novel insight into the pleiotropic effects by statins.ClinicalTrials.gov NCT01389388.

  20. Managing hypercholesterolemia and preventing cardiovascular events in elderly and younger Chinese adults: focus on rosuvastatin

    Directory of Open Access Journals (Sweden)

    Wang Z

    2013-12-01

    Full Text Available Zhen Wang, Junbo GeDepartment of Cardiology, Zhongshan Hospital, Shanghai, People's Republic of ChinaAbstract: Coronary heart disease (CHD is the leading cause of death worldwide. The efficacy and safety of statins in primary and secondary prevention of CHD is confirmed in several large studies, and rosuvastatin is the latest statin on market. We review the published literature on rosuvastatin in Chinese people. The pharmacokinetics of rosuvastatin in Chinese is somewhat different from that in Caucasians, but this does not influence the linear relationship between dosage and efficacy and with no drug accumulation. Rosuvastatin 5–20 mg/day is effective and safe in decreasing low-density lipoprotein cholesterol in both younger and elderly patients with hypercholesterolemia, even in very elderly patients. Rosuvastatin also shows anti-inflammatory and antiatherosclerosis features, such as reducing carotid intima-media thickness and plaque area. Rosuvastatin can also improve the prognosis of Chinese CHD patients, such as in the case of acute myocardial infarction. Its adverse-event rate is low and comparable to other statins. In conclusion, rosuvastatin is effective and safe for younger or elderly Chinese patients.Keywords: rosuvastatin, Chinese, younger, elderly

  1. Assessment of Pharmacokinetic Interactions Between Obeticholic Acid and Caffeine, Midazolam, Warfarin, Dextromethorphan, Omeprazole, Rosuvastatin, and Digoxin in Phase 1 Studies in Healthy Subjects.

    Science.gov (United States)

    Edwards, Jeffrey E; Eliot, Lise; Parkinson, Andrew; Karan, Sharon; MacConell, Leigh

    2017-09-01

    Obeticholic acid (OCA), a potent and selective farnesoid X receptor agonist, is indicated for the treatment of primary biliary cholangitis (PBC). We investigated the potential drug-drug interaction effect of OCA on metabolic CYP450 enzymes and drug transporters. Five phase 1 single-center, open-label, fixed-sequence, inpatient studies were conducted in healthy adult subjects to evaluate the effect of oral daily doses of 10 or 25 mg OCA on single-dose plasma pharmacokinetics of specific probe substrates for enzymes CYP1A2 (caffeine, R-warfarin), CYP3A (midazolam, R-warfarin), CYP2C9 (S-warfarin), CYP2D6 (dextromethorphan), CYP2C19 (omeprazole), and drug transporters, BCRP/OATP1B1/OATP1B3 (rosuvastatin), and P-gp (digoxin). OCA showed no substantial suppression/inhibition of S-warfarin, digoxin, and dextromethorphan and weak interactions with caffeine, omeprazole, rosuvastatin, and midazolam. The maximal pharmacodynamic responses (E max ) to warfarin-based INR, PT, and aPTT were reduced by 11%, 11%, and 1%, respectively, for the 10-mg dose group and by 7%, 7% and 0%, respectively, for the 25-mg dose group. Overall, drugs dosed in combination with OCA were well tolerated, and most adverse events were mild in severity. No clinically important trends were noted in laboratory evaluations, vital signs, or 12-lead ECGs. In these studies, OCA showed weak to no suppression/inhibition of metabolic enzymes and drug transporters at the highest recommended therapeutic dose in patients with PBC. On the basis on these analyses, monitoring and maintenance of target INR range are required during coadministration of OCA with drugs that are metabolized by CYP1A2 (R-warfarin). Intercept Pharmaceuticals, Inc.

  2. Radio Astronomers Develop New Technique for Studying Dark Energy

    Science.gov (United States)

    2010-07-01

    Pioneering observations with the National Science Foundation's giant Robert C. Byrd Green Bank Telescope (GBT) have given astronomers a new tool for mapping large cosmic structures. The new tool promises to provide valuable clues about the nature of the mysterious "dark energy" believed to constitute nearly three-fourths of the mass and energy of the Universe. Dark energy is the label scientists have given to what is causing the Universe to expand at an accelerating rate. While the acceleration was discovered in 1998, its cause remains unknown. Physicists have advanced competing theories to explain the acceleration, and believe the best way to test those theories is to precisely measure large-scale cosmic structures. Sound waves in the matter-energy soup of the extremely early Universe are thought to have left detectable imprints on the large-scale distribution of galaxies in the Universe. The researchers developed a way to measure such imprints by observing the radio emission of hydrogen gas. Their technique, called intensity mapping, when applied to greater areas of the Universe, could reveal how such large-scale structure has changed over the last few billion years, giving insight into which theory of dark energy is the most accurate. "Our project mapped hydrogen gas to greater cosmic distances than ever before, and shows that the techniques we developed can be used to map huge volumes of the Universe in three dimensions and to test the competing theories of dark energy," said Tzu-Ching Chang, of the Academia Sinica in Taiwan and the University of Toronto. To get their results, the researchers used the GBT to study a region of sky that previously had been surveyed in detail in visible light by the Keck II telescope in Hawaii. This optical survey used spectroscopy to map the locations of thousands of galaxies in three dimensions. With the GBT, instead of looking for hydrogen gas in these individual, distant galaxies -- a daunting challenge beyond the technical

  3. Managing hypercholesterolemia and preventing cardiovascular events in elderly and younger Chinese adults: focus on rosuvastatin.

    Science.gov (United States)

    Wang, Zhen; Ge, Junbo

    2014-01-01

    Coronary heart disease (CHD) is the leading cause of death worldwide. The efficacy and safety of statins in primary and secondary prevention of CHD is confirmed in several large studies, and rosuvastatin is the latest statin on market. We review the published literature on rosuvastatin in Chinese people. The pharmacokinetics of rosuvastatin in Chinese is somewhat different from that in Caucasians, but this does not influence the linear relationship between dosage and efficacy and with no drug accumulation. Rosuvastatin 5-20 mg/day is effective and safe in decreasing low-density lipoprotein cholesterol in both younger and elderly patients with hypercholesterolemia, even in very elderly patients. Rosuvastatin also shows anti-inflammatory and anti-atherosclerosis features, such as reducing carotid intima-media thickness and plaque area. Rosuvastatin can also improve the prognosis of Chinese CHD patients, such as in the case of acute myocardial infarction. Its adverse-event rate is low and comparable to other statins. In conclusion, rosuvastatin is effective and safe for younger or elderly Chinese patients.

  4. A pharmacokinetic and pharmacodynamic drug interaction between rosuvastatin and valsartan in healthy subjects

    Directory of Open Access Journals (Sweden)

    Jung JA

    2015-03-01

    Full Text Available Jin Ah Jung,1 Soo-Yun Lee,2 Jung-Ryul Kim,1 Jae-Wook Ko,1,2 Seong Bok Jang,3 Su Youn Nam,3 Wooseong Huh1,41Department of Clinical Pharmacology and Therapeutics, Samsung Medical Center, 2Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, 3Yuhan Research Institute, Yuhan Corporation, 4Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaPurpose: Valsartan, an angiotensin-receptor blocker, and rosuvastatin, a competitive inhibitor of the 3-hydroxy-3-methylglutaryl coenzyme A reductase, are frequently coadministered to treat patients with hypertension and dyslipidemia. The study reported here sought to evaluate the pharmacokinetic and pharmacodynamic interactions between rosuvastatin and valsartan in healthy Korean subjects. Subjects and methods: Thirty healthy male Korean subjects were administered with rosuvastatin (20 mg/day, valsartan (160 mg/day, and both drugs concomitantly for 4 days in a randomized, open-label, multiple-dose, three-treatment, three-period crossover study. Plasma concentrations of rosuvastatin, N-desmethyl rosuvastatin, and valsartan were determined using validated high-performance liquid chromatography with tandem mass spectrometry. Lipid profiles and vital signs (systolic and diastolic blood pressure and pulse rate were measured for the pharmacodynamic assessment.Results: For rosuvastatin, the geometric mean ratios (90% confidence intervals [CIs] of coadministration to mono-administration were 0.8809 (0.7873-0.9857 for maximum plasma concentration at steady state and 0.9151 (0.8632-0.9701 for area under the concentration–time curve (AUC over a dosing interval at steady state. For valsartan, the geometric mean ratios (90% CIs of those were 0.9300 (0.7946-1.0884 and 1.0072 (0.8893-1.1406, respectively. There were no significant differences in the metabolic ratio of N

  5. Add-on-Statin Extended Release Nicotinic Acid/Laropiprant but Not the Switch to High-Dose Rosuvastatin Lowers Blood Pressure: An Open-Label Randomized Study

    Directory of Open Access Journals (Sweden)

    Anastazia Kei

    2011-01-01

    Full Text Available Introduction. Nicotinic acid (NA and statins have been associated with reductions in blood pressure (BP. Patients and Methods. We recruited 68 normotensive and hypertensive dyslipidemic patients who were treated with a conventional statin dose and had not achieved lipid targets. Patients were randomized to switch to high-dose rosuvastatin (40 mg/day or to add-on current statin treatment with extended release (ER NA/laropiprant (1000/20 mg/day for the first 4 weeks followed by 2000/40 mg/day for the next 8 weeks for 3 months. Results. Switching to rosuvastatin 40 mg/day was not associated with significant BP alterations. In contrast, the addition of ER-NA/laropiprant to current statin treatment resulted in a 7% reduction of systolic BP (from 134±12 to 125±10 mmHg, <.001 versus baseline and =.01 versus rosuvastatin group and a 5% reduction of diastolic BP (from 81±9 to 77±6 mmHg, =.009 versus baseline and =.01 versus rosuvastatin group. These reductions were significant only in the subgroup of hypertensives and were independent of the hypolipidemic effects of ER-NA/laropiprant. Conclusions. Contrary to the switch to high-dose rosuvastatin, the addition of ER-NA/laropiprant to statin treatment was associated with significant reductions in both systolic and diastolic BP.

  6. Antiatherosclerotic effects of long-term maximally intensive statin therapy after acute coronary syndrome: insights from Study of Coronary Atheroma by Intravascular Ultrasound: Effect of Rosuvastatin Versus Atorvastatin.

    Science.gov (United States)

    Puri, Rishi; Nissen, Steven E; Shao, Mingyuan; Ballantyne, Christie M; Barter, Philip J; Chapman, M John; Erbel, Raimund; Libby, Peter; Raichlen, Joel S; Uno, Kiyoko; Kataoka, Yu; Nicholls, Stephen J

    2014-11-01

    Patients with acute coronary syndromes (ACS) display diffuse coronary atheroma instability and heightened risk of early and late recurrent coronary events. We compared the long-term antiatherosclerotic efficacy of high-intensity statins in patients with ACS when compared with stable disease. Study of Coronary Atheroma by Intravascular Ultrasound: Effect of Rosuvastatin Versus Atorvastatin (SATURN) used serial intravascular ultrasound measures of coronary atheroma volume in patients treated with rosuvastatin 40 mg or atorvastatin 80 mg for 24 months. The overall effect of high-intensity statins on the change in coronary percent atheroma volume and major adverse cardiovascular events (death/nonfatal myocardial infarction/coronary revascularization) were evaluated in this post hoc analysis. When compared with non-ACS patients (n=678), patients with ACS (n=361) were younger, actively smoking, and have had a previous myocardial infarction (all P<0.001). At baseline, patients with ACS exhibited lower high-density lipoprotein cholesterol (43.5±11 versus 45.8±11 mg/dL; P=0.002), a higher apolipoprotein B: apolipoprotein A-1 ratio (0.90±0.24 versus 0.83±0.24; P<0.001) and greater percent atheroma volume (37.3±8.5% versus 35.9±8.1%; P=0.01) when compared with non-ACS patients. Despite similar achieved levels of lipid and inflammatory markers after high-intensity statin therapy, patients with ACS demonstrated greater percent atheroma volume regression than non-ACS patients (-1.46±0.14 versus -0.89±0.13; P=0.003). After propensity-weighted multivariable adjustment, baseline percent atheroma volume (P<0.001) and an ACS clinical presentation (P=0.02) independently associated with plaque regression. The 24-month major adverse cardiovascular events-free survival was similar between patients with ACS and non-ACS (90.6 versus 92.9%; P=0.25). Long-term high-intensity statin therapy caused greater plaque regression and comparable major adverse cardiovascular events rates in

  7. Perioperative Rosuvastatin in Cardiac Surgery.

    Science.gov (United States)

    Zheng, Zhe; Jayaram, Raja; Jiang, Lixin; Emberson, Jonathan; Zhao, Yan; Li, Qi; Du, Juan; Guarguagli, Silvia; Hill, Michael; Chen, Zhengming; Collins, Rory; Casadei, Barbara

    2016-05-05

    Complications after cardiac surgery are common and lead to substantial increases in morbidity and mortality. Meta-analyses of small randomized trials have suggested that perioperative statin therapy can prevent some of these complications. We randomly assigned 1922 patients in sinus rhythm who were scheduled for elective cardiac surgery to receive perioperative rosuvastatin (at a dose of 20 mg daily) or placebo. The primary outcomes were postoperative atrial fibrillation within 5 days after surgery, as assessed by Holter electrocardiographic monitoring, and myocardial injury within 120 hours after surgery, as assessed by serial measurements of the cardiac troponin I concentration. Secondary outcomes included major in-hospital adverse events, duration of stay in the hospital and intensive care unit, left ventricular and renal function, and blood biomarkers. The concentrations of low-density lipoprotein cholesterol and C-reactive protein after surgery were lower in patients assigned to rosuvastatin than in those assigned to placebo (PSTICS ClinicalTrials.gov number, NCT01573143.).

  8. Enterohepatic disposition of rosuvastatin in pigs and the impact of concomitant dosing with cyclosporine and gemfibrozil.

    Science.gov (United States)

    Bergman, Ebba; Lundahl, Anna; Fridblom, Patrik; Hedeland, Mikael; Bondesson, Ulf; Knutson, Lars; Lennernäs, Hans

    2009-12-01

    The hepatobiliary transport and local disposition of rosuvastatin in pig were investigated, along with the impact of concomitant dosing with two known multiple transport inhibitors; cyclosporine and gemfibrozil. Rosuvastatin (80 mg) was administered as an intrajejunal bolus dose in treatments I, II, and III (TI, TII, and TIII, respectively; n = 6 per treatment). Cyclosporine (300 mg) and gemfibrozil (600 mg) were administered in addition to the rosuvastatin dose in TII and TIII, respectively. Cyclosporine was administered as a 2-h intravenous infusion and gemfibrozil as an intrajejunal bolus dose. In treatment IV (TIV, n = 4) 5.9 mg of rosuvastatin was administered as an intravenous bolus dose. The study was conducted using a pig model, which enabled plasma sampling from the portal (VP), hepatic (VH), and femoral veins and bile from the common hepatic duct. The biliary recoveries of the administered rosuvastatin dose were 9.0 +/- 3.5 and 35.7 +/- 15.6% in TI and TIV, respectively. Rosuvastatin was highly transported into bile as shown by the median AUC(bile)/AUC(VH) ratio in TI of 1770 (1640-11,300). Gemfibrozil did not have an effect on the plasma pharmacokinetics of rosuvastatin, most likely because the unbound inhibitor concentrations did not exceed the reported IC(50) values. However, cyclosporine significantly reduced the hepatic extraction of rosuvastatin (TI, 0.89 +/- 0.06; TII, 0.46 +/- 0.13) and increased the AUC(VP) and AUC(VH) by 1.6- and 9.1-fold, respectively. In addition, the biliary exposure and f(e, bile) were reduced by approximately 50%. The strong effect of cyclosporine was in accordance with inhibition of sinusoidal uptake transporters, such as members of the organic anion-transporting polypeptide family, rather than canalicular transporters.

  9. Is rosuvastatin protective against on noise-induced oxidative stress in rat serum?

    Directory of Open Access Journals (Sweden)

    Emine Rabia Koc

    2015-01-01

    Full Text Available Noise, one of the main components of modern society, has become an important environmental problem. Noise is not only an irritating sound, but also a stress factor leading to serious health problems. In this study, we have investigated possible effects of rosuvastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, thought to have an antioxidant effect, on noise-induced oxidative stress in the serum of rat models. Thirty-two male Wistar albino rats were used. In order to ease their adaptation, 2 weeks before the experiment, the rats were divided into four groups (with eight rats per each group: Noise exposure plus rosuvastatin usage, only noise exposure, only rosuvastatin usage and control. After the data had been collected, oxidant (Malondialdehyde, nitric oxide [NO], protein carbonyl [PC] and antioxidant (superoxide dismutase [SOD], glutathione peroxidase [GSH-PX], catalase [CAT] parameters were analyzed in the serum. Results indicated that SOD values were found to be significantly lower, while PC values in serum were remarkably higher in the group that was exposed to only noise. GSH-Px values in serum dramatically increased in the group on which only rosuvastatin was used. During noise exposure, the use of rosuvastatin caused significantly increased CAT values, whereas it resulted in reduced PC and NO values in serum. In conclusion, our data show that noise exposure leads to oxidative stress in rat serum; however, rosuvastatin therapy decreases the oxidative stress caused by noise exposure.

  10. Astronomical Observations Astronomy and the Study of Deep Space

    CERN Document Server

    2010-01-01

    Our Search for knowledge about the universe has been remarkable, heartbreaking, fantastical, and inspiring, and this search is just beginning. Astronomical Observations is part of a 7 book series that takes readers through a virtual time warp of our discovery. From the nascent space programs of the 1960's to today's space tourism and the promise of distant planet colonization, readers will be transfixed. Throughout this journey of the mind, Earth-bound explorers gain keen insight into the celestial phenomena that have fascinated humans for centuries. Thrilling narratives about indefatigable sc

  11. Astronomical Ecosystems

    Science.gov (United States)

    Neuenschwander, D. E.; Finkenbinder, L. R.

    2004-05-01

    Just as quetzals and jaguars require specific ecological habitats to survive, so too must planets occupy a tightly constrained astronomical habitat to support life as we know it. With this theme in mind we relate the transferable features of our elementary astronomy course, "The Astronomical Basis of Life on Earth." Over the last five years, in a team-taught course that features a spring break field trip to Costa Rica, we have introduced astronomy through "astronomical ecosystems," emphasizing astronomical constraints on the prospects for life on Earth. Life requires energy, chemical elements, and long timescales, and we emphasize how cosmological, astrophysical, and geological realities, through stabilities and catastrophes, create and eliminate niches for biological life. The linkage between astronomy and biology gets immediate and personal: for example, studies in solar energy production are followed by hikes in the forest to examine the light-gathering strategies of photosynthetic organisms; a lesson on tides is conducted while standing up to our necks in one on a Pacific beach. Further linkages between astronomy and the human timescale concerns of biological diversity, cultural diversity, and environmental sustainability are natural and direct. Our experience of teaching "astronomy as habitat" strongly influences our "Astronomy 101" course in Oklahoma as well. This "inverted astrobiology" seems to transform our student's outlook, from the universe being something "out there" into something "we're in!" We thank the SNU Science Alumni support group "The Catalysts," and the SNU Quetzal Education and Research Center, San Gerardo de Dota, Costa Rica, for their support.

  12. Renal effects of atorvastatin and rosuvastatin in patients with diabetes who have progressive renal disease (PLANET I)

    DEFF Research Database (Denmark)

    de Zeeuw, Dick; Anzalone, Deborah A; Cain, Valerie A

    2015-01-01

    , angiotensin receptor blockers, or both. We randomly assigned participants to atorvastatin 80 mg, rosuvastatin 10 mg, or rosuvastatin 40 mg for 52 weeks. The primary endpoint was change from baseline to week 52 of mean UPCR in each treatment group. The study is registered with ClinicalTrials.gov, number NCT......00296374. FINDINGS: We enrolled 353 patients: 118 were assigned to rosuvastatin 10 mg, 124 to rosuvastatin 40 mg, and 111 to atorvastatin 80 mg; of these, 325 were included in the intention-to-treat population. UPCR baseline:week 52 ratio was 0·87 (95% CI 0·77-0·99; p=0·033) with atorvastatin 80 mg, 1...... with ClinicalTrials.gov, NCT00296400). In this analysis, atorvastatin 80 mg lowered UPCR significantly more than did rosuvastatin 10 mg (-15·6%, 95% CI -28·3 to -0·5; p=0·043) and rosuvastatin 40 mg (-18·2%, -30·2 to -4·2; p=0·013). Adverse events occurred in 69 (60%) of 116 patients in the rosuvastatin 10 mg...

  13. Ascorbic acid supplementation partially prevents the delayed reproductive development in juvenile male rats exposed to rosuvastatin since prepuberty.

    Science.gov (United States)

    Leite, Gabriel Adan Araújo; Figueiredo, Thamiris Moreira; Sanabria, Marciana; Dias, Ana Flávia Mota Gonçalves; Silva, Patrícia Villela E; Martins Junior, Airton da Cunha; Barbosa Junior, Fernando; Kempinas, Wilma De Grava

    2017-10-01

    Dyslipidemias are occurring earlier in the population due to the increase of obesity and bad eating habits. Rosuvastatin inhibits the enzyme HMG-CoA reductase, decreasing total cholesterol. Ascorbic acid is an important antioxidant compound for male reproductive system. This study aimed to evaluate whether ascorbic acid supplementation may prevent the reproductive damage provoked by rosuvastatin administration at prepuberty. Male pups were distributed into six experimental groups that received saline solution 0.9%, 3 or 10mg/kg/day of rosuvastatin, 150mg/day of ascorbic acid, or 150mg/day of ascorbic acid associated with 3 or 10mg/kg/day of rosuvastatin from post-natal day (PND) 23 until PND53. Rosuvastatin-treated groups showed delayed puberty installation, androgen depletion and impairment on testicular and epididymal morphology. Ascorbic acid partially prevented these reproductive damages. In conclusion, rosuvastatin exposure is a probable risk to reproductive development and ascorbic acid supplementation may be useful to prevent the reproductive impairment of rosuvastatin exposure. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Effects of statin therapy according to plasma high-sensitivity C-reactive protein concentration in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA): a retrospective analysis

    DEFF Research Database (Denmark)

    McMurray, John J V; Kjekshus, John; Gullestad, Lars

    2009-01-01

    -generating study, we found a significant interaction between hs-CRP and the effect of rosuvastatin for most end points whereby rosuvastatin treatment was associated with better outcomes in patients with hs-CRP > or = 2.0 mg/L. CLINICAL TRIAL REGISTRATION INFORMATION: URL: http://www.clinicaltrials.gov. Unique...

  15. Platelet reactivity in response to loading dose of atorvastatin or rosuvastatin in patients with stable coronary disease before percutaneous coronary intervention: The STATIPLAT randomized study.

    Science.gov (United States)

    Godino, Cosmo; Pavon, Anna Giulia; Mangieri, Antonio; Salerno, Anna; Cera, Michela; Monello, Alberto; Chieffo, Alaide; Magni, Valeria; Cappelletti, Alberto; Margonato, Alberto; Colombo, Antonio

    2017-08-01

    The acute effects of statin loading dose (LD) on platelet reactivity in patients with chronic stable angina (CSA) are not completely clear. We hypothesized that LDs of atorvastatin and rosuvastatin have different pharmacodynamic acute effects on platelet aggregability in CSA patients with baseline normal platelet reactivity while on dual antiplatelet therapy (DAPT). From September 2011 to February 2014, all consecutive CSA patients on chronic DAPT (aspirin and clopidogrel) were evaluated before elective percutaneous coronary intervention (PCI). An initial assessment of platelet reactivity in response to thrombin receptor agonist, ADP, and ASP (respectively, indicative of the response to clopidogrel and aspirin) was performed with impedance aggregometry. Patients with high platelet reactivity to ADP test (area under the curve >47) were excluded. The remaining patients were randomized into 3 treatment groups: Group A, atorvastatin LD 80 mg; Group B, rosuvastatin LD 40 mg; and Group C, no statin LD (control group). A second assessment of platelet reactivity was performed ≥12 hours after statin LD. 682 patients were screened and 145 were randomized into the 3 groups. At baseline and after statin LD, no significant difference was found in platelet reactivity in response to 3 different agonists between the 3 groups. Subgroup analysis showed that platelet reactivity to ADP test was significantly lower in patients chronically treated with low-dose statins (n = 94) compared with statin-naïve patients (n = 51; 15.32 ± 1.50 vs 18.59 ± 1.30; P = 0.007). Loading dose of atorvastatin (80 mg) or rosuvastatin (40 mg) did not induce significant variation in platelet reactivity in CSA patients with baseline reduced platelet reactivity as in chronic DAPT. Our data confirm that chronic concomitant treatment with low-dose statins and clopidogrel resulted in significantly lower platelet reactivity compared with clopidogrel alone. © 2017 Wiley Periodicals, Inc.

  16. Efficacy of Rosuvastatin in Children With Homozygous Familial Hypercholesterolemia and Association With Underlying Genetic Mutations

    DEFF Research Database (Denmark)

    Stein, Evan A; Dann, Eldad J; Wiegman, Albert

    2017-01-01

    formally evaluated in, or approved for, HoFH children. OBJECTIVES: The authors sought to assess the LDL-C efficacy of rosuvastatin versus placebo in HoFH children, and the relationship with underlying genetic mutations. METHODS: This was a randomized, double-blind, 12-week, crossover study of rosuvastatin...... 20 mg versus placebo, followed by 12 weeks of open-label rosuvastatin. Patients discontinued all lipid-lowering treatment except ezetimibe and/or apheresis. Clinical and laboratory assessments were performed every 6 weeks. The relationship between LDL-C response and genetic mutations was assessed....../dl (range: 130 to 700 mg/dl) on rosuvastatin, producing a mean 85.4 mg/dl (22.3%) difference (p = 0.005). Efficacy was similar regardless of age or use of ezetimibe or apheresis, and was maintained for 12 weeks. Adverse events were few and not serious. Patients with 2 defective versus 2 negative LDL...

  17. Rosuvastatin

    Science.gov (United States)

    ... asleep or staying asleep depression joint pain headache memory loss or forgetfulness confusion Some side effects can ... is important to keep all medication out of sight and reach of children as many containers (such ...

  18. [Rosuvastatin improves insulin sensitivity in overweight rats induced by high fat diet. Role of SIRT1 in adipose tissue].

    Science.gov (United States)

    Valero-Muñoz, María; Martín-Fernández, Beatriz; Ballesteros, Sandra; Cachofeiro, Victoria; Lahera, Vicente; de Las Heras, Natalia

    2014-01-01

    To study the effects of rosuvastatin on insulin resistance in overweight rats induced by high fat diet, as well as potential mediators. We used male Wistar rats fed with a standard diet (CT) or high fat diet (33.5% fat) (HFD); half of the animals HFD were treated with rosuvastatin (15mg/kg/day) (HFD+Rosu) for 7 weeks. HFD rats showed increased body, epididymal and lumbar adipose tissue weights. Treatment with Rosu did not modify body weight or the weight of the adipose packages in HFD rat. Plasma glucose and insulin levels and HOMA index were higher in HFD rats, and rosuvastatin treatment reduced them. Leptin/adiponectin ratio in plasma and lumbar adipose tissue were higher in HDF rats, and were reduced by rosuvastatin. SIRT-1, PPAR-γ and GLUT-4 protein expression in lumbar adipose tissue were lower in HFD rats and Rosu normalized expression of the three mediators. Rosuvastatin ameliorates insulin sensitivity induced by HFD in rats. This effect is mediated by several mechanisms including reduction of leptin and enhancement of SIRT-1, PPAR-γ and GLUT-4 expression in white adipose tissue. SIRT1 could be considered a major mediator of the beneficial effects of rosuvastatin on insulin sensitivity in overweight rats induced by diet. Copyright © 2013 Sociedad Española de Arteriosclerosis. Published by Elsevier España. All rights reserved.

  19. Effects of maximal atorvastatin and rosuvastatin treatment on markers of glucose homeostasis and inflammation

    Science.gov (United States)

    Recent studies show that statin therapy, while effective at lowering the risk of cardiovascular disease (CVD), may be associated with an increased risk of diabetes. To test the effects of maximal dosages of rosuvastatin and atorvastatin (80mg/day and 40mg/day, respectively) we obtained frozen serum ...

  20. Astronomical Cybersketching

    CERN Document Server

    Grego, Peter

    2009-01-01

    Outlines the techniques involved in making observational sketches and more detailed 'scientific' drawings of a wide variety of astronomical subjects using modern digital equipment; primarily PDAs and tablet PCs. This book also discusses about choosing hardware and software

  1. Short-term memory loss associated with rosuvastatin.

    Science.gov (United States)

    Galatti, Laura; Polimeni, Giovanni; Salvo, Francesco; Romani, Marcello; Sessa, Aurelio; Spina, Edoardo

    2006-08-01

    Memory loss and cognitive impairment have been reported in the literature in association with several 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins), but we found no published case reports associated with rosuvastatin. To our knowledge, this is the first reported case of rosuvastatin-related short-term memory loss. A 53-year-old Caucasian man with hypercholesterolemia experienced memory loss after being treated with rosuvastatin 10 mg/day. He had no other concomitant conditions or drug therapies. After discontinuation of rosuvastatin, the neuropsychiatric adverse reaction resolved gradually, suggesting a probable drug association. During the following year, the patient remained free from neuropsychiatric disturbances. Clinicians should be aware of possible adverse cognitive reactions during statin therapy, including rosuvastatin.

  2. Considerations for the Use of STEREO -HI Data for Astronomical Studies

    Energy Technology Data Exchange (ETDEWEB)

    Tappin, S. J., E-mail: james.tappin@stfc.ac.uk [RAL Space, STFC Rutherford Appleton Laboratory, Harwell Oxford, Didcot, Oxon. OX11 0QX (United Kingdom)

    2017-04-01

    Recent refinements to the photometric calibrations of the Heliospheric Imagers (HI) on board the Solar TErrestrial RElations Observatory ( STEREO ) have revealed a number of subtle effects in the measurement of stellar signals with those instruments. These effects need to be considered in the interpretation of STEREO -HI data for astronomy. In this paper we present an analysis of these effects and how to compensate for them when using STEREO -HI data for astronomical studies. We determine how saturation of the HI CCD detectors affects the apparent count rates of stars after the on-board summing of pixels and exposures. Single-exposure calibration images are analyzed and compared with binned and summed science images to determine the influence of saturation on the science images. We also analyze how the on-board cosmic-ray scrubbing algorithm affects stellar images. We determine how this interacts with the variations of instrument pointing to affect measurements of stars. We find that saturation is a significant effect only for the brightest stars, and that its onset is gradual. We also find that degraded pointing stability, whether of the entire spacecraft or of the imagers, leads to reduced stellar count rates and also increased variation thereof through interaction with the on-board cosmic-ray scrubbing algorithm. We suggest ways in which these effects can be mitigated for astronomical studies and also suggest how the situation can be improved for future imagers.

  3. Evaluation of a potential transporter-mediated drug interaction between rosuvastatin and pradigastat, a novel DGAT-1 inhibitor.

    Science.gov (United States)

    Kulmatycki, Kenneth; Hanna, Imad; Meyers, Dan; Salunke, Atish; Movva, Aishwarya; Majumdar, Tapan; Natrillo, Adrienne; Vapurcuyan, Arpine; Rebello, Sam; Sunkara, Gangadhar; Chen, Jin

    2015-05-01

    An in vitro drugdrug interaction (DDI) study was performed to assess the potential for pradigastat to inhibit breast cancer resistance protein (BCRP), organic anion-transporting polypeptide (OATP), and organic anion transporter 3 (OAT3) transport activities. To understand the relevance of these in vitro findings, a clinical pharmacokinetic DDI study using rosuvastatin as a BCRP, OATP, and OAT3 probe substrate was conducted. The study used cell lines that stably expressed or over-expressed the respective transporters. The clinical study was an open-label, single sequence study where subjects (n = 36) received pradigastat (100 mg once daily x 3 days thereafter 40 mg once daily) and rosuvastatin (10 mg once daily), alone and in combination. Pradigastat inhibited BCRP-mediated efflux activity in a dose-dependent fashion in a BCRP over-expressing human ovarian cancer cell line with an IC(50) value of 5 μM. Similarly, pradigastat inhibited OATP1B1, OATP1B3 (estradiol 17β glucuronide transport), and OAT3 (estrone 3 sulfate transport) activity in a concentrationdependent manner with estimated IC(50) values of 1.66 ± 0.95 μM, 3.34 ± 0.64 μM, and 0.973 ± 0.11 μM, respectively. In the presence of steady state pradigastat concentrations, AUC(τ, ss) of rosuvastatin was unchanged and its Cmax,ss decreased by 14% (5.30 and 4.61 ng/mL when administered alone and coadministered with pradigastat, respectively). Pradigastat AUC(τ, ss) and C(max, ss) were unchanged when coadministered with rosuvastatin at steady state. Both rosuvastatin and pradigastat were well tolerated. These data indicate no clinically relevant pharmacokinetic interaction between pradigastat and rosuvastatin.

  4. Rosuvastatin and the JUPITER trial: critical appraisal of a lifeless planet in the galaxy of primary prevention.

    Science.gov (United States)

    López, Antonio; Wright, James M

    2012-01-01

    In November 2008, the JUPITER trial was published in the New England Journal of Medicine. JUPITER is an acronym for Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin. It was an AstraZeneca sponsored randomized double-blind trial comparing rosuvastatin 20 mg with placebo in 17,802 apparently healthy men and women with LDL cholesterol JUPITER trial have been widely publicized, and based on the trial, the main regulatory agencies have approved rosuvastatin for the indication of primary prevention of vascular events. However, the interpretation and clinical implications of the JUPITER trial have been questioned and remain controversial. The objective of this commentary is to evaluate the relevance, design, results, and conclusions of the JUPITER study.

  5. Astronomical optics

    CERN Document Server

    Schroeder, Daniel J

    1988-01-01

    Written by a recognized expert in the field, this clearly presented, well-illustrated book provides both advanced level students and professionals with an authoritative, thorough presentation of the characteristics, including advantages and limitations, of telescopes and spectrographic instruments used by astronomers of today.Key Features* Written by a recognized expert in the field* Provides both advanced level students and professionals with an authoritative, thorough presentation of the characteristics, including advantages and limitations, of telescopes and spectrographic i

  6. A STUDY ON LOWER SECONDARY SCHOOL PUPILS’ PERCEPTIONS OF CERTAIN ASTRONOMICAL PHENOMENA AND CELESTIAL BODIES

    Directory of Open Access Journals (Sweden)

    VIRGINIA SASU

    2014-01-01

    Full Text Available The main purpose of this paper is to reveal certain misconceptions of astronomical phenomena and of celestial bodies that lower secondary school pupils have and which might represent an obstacle in the process of acquiring knowledge of astronomy, geography, and physics. We applied a questionnaire to a group of 26 pupils in the 6th grade at Colegiul Naţional Pedagogic „Gh. Lazăr” (“Gh. Lazăr National Pedagogical College in Cluj-Napoca, in the school year 2010 – 2011. The questionnaire consisted of six independent topics: the alternation of day and night, the seasons, the Moon, the solar system, the constellations and the speed of light. Pupils’ answers to these questions emphasize the importance of the study of astronomy as a school subject in order to facilitate building up appropriate mind constructs of the highest degree of objectivity about the world, about the environment we live in.

  7. Plasma Drug Concentrations of Orally Administered Rosuvastatin in Hispaniolan Amazon Parrots (Amazona ventralis).

    Science.gov (United States)

    Beaufrère, Hugues; Papich, Mark G; Brandão, João; Nevarez, Javier; Tully, Thomas N

    2015-03-01

    Atherosclerotic diseases are common in pet psittacine birds, in particular Amazon parrots. While hypercholesterolemia and dyslipidemia have not definitely been associated with increased susceptibility to atherosclerosis in parrots, these are important and well-known risk factors in humans. Therefore statin drugs such as rosuvastatin constitute the mainstay of human treatment of dyslipidemia and the prevention of atherosclerosis. No pharmacologic studies have been performed in psittacine birds despite the high prevalence of atherosclerosis in captivity. Thirteen Hispaniolan Amazon parrots were used to test a single oral dose of 10 mg/kg of rosuvastatin with blood sampling performed according to a balanced incomplete block design over 36 hours. Because low plasma concentrations were produced in the first study, a subsequent pilot study using a dose of 25 mg/kg in 2 Amazon parrots was performed. Most plasma samples for the 10 mg/kg dose and all samples for the 25 mg/kg dose had rosuvastatin concentration below the limits of quantitation. For the 10 mg/kg study, the median peak plasma concentration and time to peak plasma concentration were 0.032 μg/mL and 2 hours, respectively. Our results indicate that rosuvastatin does not appear suitable in Amazon parrots as compounded and used at the dose in this study. Pharmacodynamic studies investigating lipid-lowering effects of statins rather than pharmacokinetic studies may be more practical and cost effective in future studies to screen for a statin with more ideal properties for potential use in psittacine dyslipidemia and atherosclerotic diseases.

  8. Safety and vasopressor effect of rosuvastatin in septic patients

    Directory of Open Access Journals (Sweden)

    Hanaa A. El Gendy

    2014-07-01

    Conclusions: Rosuvastatin 20 mg/day in septic patients increased number ABPSPD, decreased time to initial ABPSPD, norepinephrine dose and duration, with no significant elevation in transaminases or CPK.

  9. Astronomical chemistry.

    Science.gov (United States)

    Klemperer, William

    2011-01-01

    The discovery of polar polyatomic molecules in higher-density regions of the interstellar medium by means of their rotational emission detected by radioastronomy has changed our conception of the universe from essentially atomic to highly molecular. We discuss models for molecule formation, emphasizing the general lack of thermodynamic equilibrium. Detailed chemical kinetics is needed to understand molecule formation as well as destruction. Ion molecule reactions appear to be an important class for the generally low temperatures of the interstellar medium. The need for the intrinsically high-quality factor of rotational transitions to definitively pin down molecular emitters has been well established by radioastronomy. The observation of abundant molecular ions both positive and, as recently observed, negative provides benchmarks for chemical kinetic schemes. Of considerable importance in guiding our understanding of astronomical chemistry is the fact that the larger molecules (with more than five atoms) are all organic.

  10. How Do Astronomers Share Data? Reliability and Persistence of Datasets Linked in AAS Publications and a Qualitative Study of Data Practices among US Astronomers

    Science.gov (United States)

    Pepe, Alberto; Goodman, Alyssa; Muench, August; Crosas, Merce; Erdmann, Christopher

    2014-08-01

    We analyze data sharing practices of astronomers over the past fifteen years. An analysis of URL links embedded in papers published by the American Astronomical Society reveals that the total number of links included in the literature rose dramatically from 1997 until 2005, when it leveled off at around 1500 per year. The analysis also shows that the availability of linked material decays with time: in 2011, 44% of links published a decade earlier, in 2001, were broken. A rough analysis of link types reveals that links to data hosted on astronomers' personal websites become unreachable much faster than links to datasets on curated institutional sites. To gauge astronomers' current data sharing practices and preferences further, we performed in-depth interviews with 12 scientists and online surveys with 173 scientists, all at a large astrophysical research institute in the United States: the Harvard-Smithsonian Center for Astrophysics, in Cambridge, MA. Both the in-depth interviews and the online survey indicate that, in principle, there is no philosophical objection to data-sharing among astronomers at this institution. Key reasons that more data are not presently shared more efficiently in astronomy include: the difficulty of sharing large data sets; over reliance on non-robust, non-reproducible mechanisms for sharing data (e.g. emailing it); unfamiliarity with options that make data-sharing easier (faster) and/or more robust; and, lastly, a sense that other researchers would not want the data to be shared. We conclude with a short discussion of a new effort to implement an easy-to-use, robust, system for data sharing in astronomy, at theastrodata.org, and we analyze the uptake of that system to-date.

  11. How do astronomers share data? Reliability and persistence of datasets linked in AAS publications and a qualitative study of data practices among US astronomers.

    Science.gov (United States)

    Pepe, Alberto; Goodman, Alyssa; Muench, August; Crosas, Merce; Erdmann, Christopher

    2014-01-01

    We analyze data sharing practices of astronomers over the past fifteen years. An analysis of URL links embedded in papers published by the American Astronomical Society reveals that the total number of links included in the literature rose dramatically from 1997 until 2005, when it leveled off at around 1500 per year. The analysis also shows that the availability of linked material decays with time: in 2011, 44% of links published a decade earlier, in 2001, were broken. A rough analysis of link types reveals that links to data hosted on astronomers' personal websites become unreachable much faster than links to datasets on curated institutional sites. To gauge astronomers' current data sharing practices and preferences further, we performed in-depth interviews with 12 scientists and online surveys with 173 scientists, all at a large astrophysical research institute in the United States: the Harvard-Smithsonian Center for Astrophysics, in Cambridge, MA. Both the in-depth interviews and the online survey indicate that, in principle, there is no philosophical objection to data-sharing among astronomers at this institution. Key reasons that more data are not presently shared more efficiently in astronomy include: the difficulty of sharing large data sets; over reliance on non-robust, non-reproducible mechanisms for sharing data (e.g. emailing it); unfamiliarity with options that make data-sharing easier (faster) and/or more robust; and, lastly, a sense that other researchers would not want the data to be shared. We conclude with a short discussion of a new effort to implement an easy-to-use, robust, system for data sharing in astronomy, at theastrodata.org, and we analyze the uptake of that system to-date.

  12. How do astronomers share data? Reliability and persistence of datasets linked in AAS publications and a qualitative study of data practices among US astronomers.

    Directory of Open Access Journals (Sweden)

    Alberto Pepe

    Full Text Available We analyze data sharing practices of astronomers over the past fifteen years. An analysis of URL links embedded in papers published by the American Astronomical Society reveals that the total number of links included in the literature rose dramatically from 1997 until 2005, when it leveled off at around 1500 per year. The analysis also shows that the availability of linked material decays with time: in 2011, 44% of links published a decade earlier, in 2001, were broken. A rough analysis of link types reveals that links to data hosted on astronomers' personal websites become unreachable much faster than links to datasets on curated institutional sites. To gauge astronomers' current data sharing practices and preferences further, we performed in-depth interviews with 12 scientists and online surveys with 173 scientists, all at a large astrophysical research institute in the United States: the Harvard-Smithsonian Center for Astrophysics, in Cambridge, MA. Both the in-depth interviews and the online survey indicate that, in principle, there is no philosophical objection to data-sharing among astronomers at this institution. Key reasons that more data are not presently shared more efficiently in astronomy include: the difficulty of sharing large data sets; over reliance on non-robust, non-reproducible mechanisms for sharing data (e.g. emailing it; unfamiliarity with options that make data-sharing easier (faster and/or more robust; and, lastly, a sense that other researchers would not want the data to be shared. We conclude with a short discussion of a new effort to implement an easy-to-use, robust, system for data sharing in astronomy, at theastrodata.org, and we analyze the uptake of that system to-date.

  13. Rosuvastatin in diabetic hemodialysis patients

    DEFF Research Database (Denmark)

    Holdaas, Hallvard; Holme, Ingar; Schmieder, Roland E

    2011-01-01

    A randomized, placebo-controlled trial in diabetic patients receiving hemodialysis showed no effect of atorvastatin on a composite cardiovascular endpoint, but analysis of the component cardiac endpoints suggested that atorvastatin may significantly reduce risk. Because the AURORA (A Study...

  14. Ascorbic acid co-administered with rosuvastatin reduces reproductive impairment in the male offspring from male rats exposed to the statin at pre-puberty.

    Science.gov (United States)

    Leite, Gabriel Adan Araújo; Figueiredo, Thamiris Moreira; Guerra, Marina Trevizan; Borges, Cibele Dos Santos; Fernandes, Fábio Henrique; Anselmo-Franci, Janete Aparecida; Kempinas, Wilma De Grava

    2018-05-18

    Obesity during childhood and adolescence is closely related to dysfunctions on lipid profile in children. Rosuvastatin is a statin that decreases serum total cholesterol. Ascorbic acid is an important antioxidant compound for male reproduction. Pre-pubertal male rats were distributed into six experimental groups that received saline solution 0.9% (vehicle), 3 or 10 mg/kg/day of rosuvastatin, 150 mg/day of ascorbic acid, or 3 or 10 mg/kg/day of rosuvastatin co-administered with 150 mg/day of ascorbic acid by gavage from post-natal day (PND)23 until PND53. Rats were maintained until adulthood and mated with nulliparous females to obtain the male offspring, whose animals were evaluated at adulthood in relation to reproductive parameters. This study is a follow up of a previous paper addressing potential effects on F0 generation only (Leite et al., 2017). Male offspring from rosuvastatin-exposed groups showed increased sperm DNA fragmentation, androgen depletion and impairment on the testicular and epididymal structure. Ascorbic acid coadministered to the fathers ameliorated the reproductive damage in the offspring. In summary, paternal exposure to rosuvastatin may affect the reproduction in the male offspring; however, paternal supplementation with ascorbic acid was able to reduce the reproductive impairment in the male offspring caused by statin treatment to the fathers. Copyright © 2018 Elsevier Ltd. All rights reserved.

  15. Korean Astronomical Calendar, Chiljeongsan

    Science.gov (United States)

    Lee, Eun Hee

    In fifteenth century Korea, there was a grand project for the astronomical calendar and instrument making by the order of King Sejong 世宗 (1418-1450). During this period, many astronomical and calendrical books including Islamic sources in Chinese versions were imported from Ming 明 China, and corrected and researched by the court astronomers of Joseon 朝鮮 (1392-1910). Moreover, the astronomers and technicians of Korea frequently visited China to study astronomy and instrument making, and they brought back useful information in the form of new published books or specifications of instruments. As a result, a royal observatory equipped with 15 types of instrument was completed in 1438. Two types of calendar, Chiljeongsan Naepyeon 七政算內篇 and Chiljeongsan Oepyeon 七政算外篇, based on the Chinese and Islamic calendar systems, respectively, were published in 1444 with a number of calendrical editions such as corrections and example supplements (假令) including calculation methods and results for solar and lunar eclipses.

  16. A Study of the Efficiency of Spatial Indexing Methods Applied to Large Astronomical Databases

    Science.gov (United States)

    Donaldson, Tom; Berriman, G. Bruce; Good, John; Shiao, Bernie

    2018-01-01

    Spatial indexing of astronomical databases generally uses quadrature methods, which partition the sky into cells used to create an index (usually a B-tree) written as database column. We report the results of a study to compare the performance of two common indexing methods, HTM and HEALPix, on Solaris and Windows database servers installed with a PostgreSQL database, and a Windows Server installed with MS SQL Server. The indexing was applied to the 2MASS All-Sky Catalog and to the Hubble Source catalog. On each server, the study compared indexing performance by submitting 1 million queries at each index level with random sky positions and random cone search radius, which was computed on a logarithmic scale between 1 arcsec and 1 degree, and measuring the time to complete the query and write the output. These simulated queries, intended to model realistic use patterns, were run in a uniform way on many combinations of indexing method and indexing level. The query times in all simulations are strongly I/O-bound and are linear with number of records returned for large numbers of sources. There are, however, considerable differences between simulations, which reveal that hardware I/O throughput is a more important factor in managing the performance of a DBMS than the choice of indexing scheme. The choice of index itself is relatively unimportant: for comparable index levels, the performance is consistent within the scatter of the timings. At small index levels (large cells; e.g. level 4; cell size 3.7 deg), there is large scatter in the timings because of wide variations in the number of sources found in the cells. At larger index levels, performance improves and scatter decreases, but the improvement at level 8 (14 min) and higher is masked to some extent in the timing scatter caused by the range of query sizes. At very high levels (20; 0.0004 arsec), the granularity of the cells becomes so high that a large number of extraneous empty cells begin to degrade

  17. Rosuvastatin does not affect human apolipoprotein A-I expression in genetically modified mice: a clue to the disputed effect of statins on HDL.

    Science.gov (United States)

    Marchesi, Marta; Parolini, Cinzia; Caligari, Silvia; Gilio, Donatella; Manzini, Stefano; Busnelli, Marco; Cinquanta, Paola; Camera, Marina; Brambilla, Marta; Sirtori, Cesare R; Chiesa, Giulia

    2011-11-01

    Besides a significant reduction of low-density lipoprotein (LDL) cholesterol, statins moderately increase high-density lipoprotein (HDL) levels. In vitro studies have indicated that this effect may be the result of an increased expression of apolipoprotein (apo)A-I, the main protein component of HDL. The aim of the present study was to investigate in vivo the effect of rosuvastatin on apoA-I expression and secretion in a transgenic mouse model for human apoA-I. Human apoA-I transgenic mice were treated for 28 days with 5, 10 or 20 mg·kg(-1) ·day(-1) of rosuvastatin, the most effective statin in raising HDL levels. Possible changes of apoA-I expression by treatment were investigated by quantitative real-time RT-PCR on RNA extracted from mouse livers. The human apoA-I secretion rate was determined in primary hepatocytes isolated from transgenic mice from each group after treatment. Rosuvastatin treatment with 5 and 10 mg·kg(-1) ·day(-1) did not affect apoA-I plasma levels, whereas a significant decrease was observed in mice treated with 20 mg·kg(-1) ·day(-1) of rosuvastatin (-16%, P < 0.01). Neither relative hepatic mRNA concentrations of apoA-I nor apoA-I secretion rates from primary hepatocytes were influenced by rosuvastatin treatment at each tested dose. In human apoA-I transgenic mice, rosuvastatin treatment does not increase either apoA-I transcription and hepatic secretion, or apoA-I plasma levels. These results support the hypothesis that other mechanisms may account for the observed HDL increase induced by statin therapy in humans. © 2011 The Authors. British Journal of Pharmacology © 2011 The British Pharmacological Society.

  18. Adding exercise to rosuvastatin treatment: influence on C-reactive protein, monocyte toll-like receptor 4 expression, and inflammatory monocyte (CD14+CD16+) population.

    Science.gov (United States)

    Coen, Paul M; Flynn, Michael G; Markofski, Melissa M; Pence, Brandt D; Hannemann, Robert E

    2010-12-01

    Statin treatment and exercise training can reduce markers of inflammation when administered separately. The purpose of this study was to determine the effect of rosuvastatin treatment and the addition of exercise training on circulating markers of inflammation including C-reactive protein (CRP), monocyte toll-like receptor 4 (TLR4) expression, and CD14+CD16+ monocyte population size. Thirty-three hypercholesterolemic and physically inactive subjects were randomly assigned to rosuvastatin (R) or rosuvastatin/exercise (RE) groups. A third group of physically active hypercholesterolemic subjects served as a control (AC). The R and RE groups received rosuvastatin treatment (10 mg/d) for 20 weeks. From week 10 to week 20, the RE group also participated in an exercise training program (3d/wk). Measurements were made at baseline (Pre), week 10 (Mid), and week 20 (Post), and included TLR4 expression on CD14+ monocytes and CD14+CD16+ monocyte population size as determined by 3-color flow cytometry. Serum CRP was quantified by enzyme-linked immunosorbent assay. TLR4 expression on CD14+ monocytes was higher in the R group at week 20. When treatment groups (R and RE) were combined, serum CRP was lower across time. Furthermore, serum CRP and inflammatory monocyte population size were lower in the RE group compared with the R group at the Post time point. When all groups (R, RE, and AC) were combined, TLR4 expression was greater on inflammatory monocytes (CD14+CD16+) compared with classic monocytes (CD14+CD16⁻) at all time points. In conclusion, rosuvastatin may influence monocyte inflammatory response by increasing TLR4 expression on circulating monocytes. The addition of exercise training to rosuvastatin treatment further lowered CRP and reduced the size of the inflammatory monocyte population, suggesting an additive anti-inflammatory effect of exercise. Copyright © 2010 Elsevier Inc. All rights reserved.

  19. Dissolution Enhancement of Rosuvastatin Calcium by Liquisolid Compact Technique

    Directory of Open Access Journals (Sweden)

    V. J. Kapure

    2013-01-01

    Full Text Available In present investigation liquisolid compact technique is investigated as a tool for enhanced dissolution of poorly water-soluble drug Rosuvastatin calcium (RVT. The model drug RVT, a HMG-Co A reductase inhibitor was formulated in form of directly compressed tablets and liquisolid compacts; and studied for in-vitro release characteristics at different dissolution conditions. In this technique, liquid medications of water insoluble drugs in non-volatile liquid vehicles can be converted into acceptably flowing and compressible powders. Formulated systems were assessed for precompression parameters like flow properties of liquisolid system, Fourior transform infra red spectra (FTIR analysis, X-ray powder diffraction (XRPD, differential scanning calorimetry (DSC, and post compression parameters like content uniformity, weight variation, hardness and friability, disintegration test, wetting time, in vitro dissolution studies, effect of dissolution volume on drug release rate, and estimation of fraction of molecularly dispersed drug in liquid medication. As liquisolid compacts demonstrated significantly higher drug release rates, we lead to conclusion that it could be a promising strategy in improving the dissolution of poor water soluble drugs and formulating immediate release solid dosage forms.

  20. Astronomy Education Research Observations from the iSTAR international Study of Astronomical Reasoning Database

    Science.gov (United States)

    Tatge, C. B.; Slater, S. J.; Slater, T. F.; Schleigh, S.; McKinnon, D.

    2016-12-01

    Historically, an important part of the scientific research cycle is to situate any research project within the landscape of the existing scientific literature. In the field of discipline-based astronomy education research, grappling with the existing literature base has proven difficult because of the difficulty in obtaining research reports from around the world, particularly early ones. In order to better survey and efficiently utilize the wide and fractured range and domain of astronomy education research methods and results, the iSTAR international Study of Astronomical Reasoning database project was initiated. The project aims to host a living, online repository of dissertations, theses, journal articles, and grey literature resources to serve the world's discipline-based astronomy education research community. The first domain of research artifacts ingested into the iSTAR database were doctoral dissertations. To the authors' great surprise, nearly 300 astronomy education research dissertations were found from the last 100-years. Few, if any, of the literature reviews from recent astronomy education dissertations surveyed even come close to summarizing this many dissertations, most of which have not been published in traditional journals, as re-publishing one's dissertation research as a journal article was not a widespread custom in the education research community until recently. A survey of the iSTAR database dissertations reveals that the vast majority of work has been largely quantitative in nature until the last decade. We also observe that modern-era astronomy education research writings reaches as far back as 1923 and that the majority of dissertations come from the same eight institutions. Moreover, most of the astronomy education research work has been done covering learners' grasp of broad knowledge of astronomy rather than delving into specific learning targets, which has been more in vogue during the last two decades. The surprisingly wide breadth

  1. Cost-effectiveness of rosuvastatin 20 mg for the prevention of cardiovascular morbidity and mortality: a Swedish economic evaluation of the JUPITER trial.

    Science.gov (United States)

    Ohsfeldt, Robert L; Olsson, Anders G; Jensen, Marie M; Gandhi, Sanjay K; Paulsson, Thomas

    2012-01-01

    This study estimated the long-term health outcomes, healthcare costs, and cost-effectiveness of rosuvastatin 20 mg therapy in primary prevention of major cardiovascular disease (CVD) in a Swedish population. Based on data from the JUPITER trial, long-term CVD outcomes with rosuvastatin vs no active treatment were estimated for patients with an elevated baseline CVD risk (Framingham CVD score >20%, sub-population of JUPITER population) and for a population similar to the total JUPITER population. Using a decision-analytic model, trial CVD event rates were combined with epidemiological and cost data specific for Sweden. First and subsequent CVD events and death were estimated over a lifetime perspective. The observed relative risk reduction was extrapolated beyond the trial duration. Incremental effectiveness was measured as life-years gained (LYG) and quality-adjusted life-years (QALYs) gained. Treating 100,000 patients with rosuvastatin 20 mg was estimated to avoid 14,692 CVD events over the lifetime (8021 non-fatal MIs, 3228 non-fatal strokes, and 4924 CVD deaths) compared to placebo. This translated into an estimated gain of 42,122 QALYs and 36,865 total life years (LYG). Rosuvastatin was both more effective and less costly over a lifetime perspective, and rosuvastatin is subsequently a dominant alternative compared to no treatment in the assessed population. Using the overall JUPITER population, rosuvastatin was dominant for the lifetime horizon. In the sensitivity analysis, rosuvastatin was the dominant treatment strategy over a 20-year time horizon, and cost-effective with an incremental cost-effectiveness ratio (cost per QALY) of SEK 1783 over a 10-year time horizon. Some model inputs were derived from literature or other data sources, but uncertainty was controlled by sensitivity analyses. Results indicate that rosuvastatin 20 mg treatment is a cost-effective option vs no-treatment in patients with Framingham CVD risk >20% in Sweden and might even be

  2. South African Astronomical Observatory

    International Nuclear Information System (INIS)

    1987-01-01

    Work at the South African Astronomical Observatory (SAAO) in recent years, by both staff and visitors, has made major contributions to the fields of astrophysics and astronomy. During 1986 the SAAO has been involved in studies of the following: galaxies; celestial x-ray sources; magellanic clouds; pulsating variables; galactic structure; binary star phenomena; nebulae and interstellar matter; stellar astrophysics; open clusters; globular clusters, and solar systems

  3. The South African astronomical observatory

    International Nuclear Information System (INIS)

    Feast, M.

    1985-01-01

    A few examples of the activities of the South African Astronomical Observatory are discussed. This includes the studying of stellar evolution, dust around stars, the determination of distances to galaxies and collaboration with space experiments

  4. Resolution of non-alcoholic steatohepatitis by rosuvastatin monotherapy in patients with metabolic syndrome.

    Science.gov (United States)

    Kargiotis, Konstantinos; Athyros, Vasilios G; Giouleme, Olga; Katsiki, Niki; Katsiki, Evangelia; Anagnostis, Panagiotis; Boutari, Chrysoula; Doumas, Michael; Karagiannis, Asterios; Mikhailidis, Dimitri P

    2015-07-07

    To investigate the effect of rosuvastatin monotherapy on non-alcoholic steatohepatitis (NASH). At present there is no effective treatment for non-alcoholic fatty liver disease or its advanced form NASH. This prospective study included 20 biopsy proven patients with NASH, metabolic syndrome (MetS) and dyslipidaemia. Biochemical parameters of the blood of the patients and an ultrasonography of the liver were performed at baseline. Then patients received lifestyle advice and were treated for a 12 mo period with rosuvastatin (10 mg/d) monotherapy. Patients were re-evaluated during the study at 3 mo intervals, during which biochemical parameters of the blood were measured including liver enzymes. A repeat biopsy and ultrasonography of the liver were performed at the end of the study in all 20 patients. Changes in liver enzymes, fasting plasma glucose, serum creatinine, serum uric acid (SUA), high sensitivity C reactive protein (hsCRP) and lipid profile were assessed every 3 mo. The primary endpoint was the resolution of NASH and the secondary endpoints were the changes in liver enzyme and lipid values. The repeat liver biopsy and ultrasonography showed complete resolution of NASH in 19 patients, while the 20(th), which had no improvement but no deterioration either, developed arterial hypertension and substantial rise in triglyceride levels during the study, probably due to changes in lifestyle including alcohol abuse. Serum alanine transaminase, aspartate transaminase, and γ-glutamyl transpeptidase were normalised by the 3(rd) treatment month (ANOVA P < 0.001), while alkaline phosphatase activities by the 6(th) treatment month (ANOVA, P = 0.01). Fasting plasma glucose and glycated haemoglobin were significantly reduced (P < 0.001). Lipid values were normalised by the 3(rd) treatment month. No patient had MetS by the 9(th) treatment month. Body mass index and waist circumference remained unchanged during the study. Thus, changes in liver pathology and function should

  5. Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective.

    Science.gov (United States)

    Kones, Richard

    2010-12-09

    The major public health concern worldwide is coronary heart disease, with dyslipidemia as a major risk factor. Statin drugs are recommended by several guidelines for both primary and secondary prevention. Rosuvastatin has been widely accepted because of its efficacy, potency, and superior safety profile. Inflammation is involved in all phases of atherosclerosis, with the process beginning in early youth and advancing relentlessly for decades throughout life. C-reactive protein (CRP) is a well-studied, nonspecific marker of inflammation which may reflect general health risk. Considerable evidence suggests CRP is an independent predictor of future cardiovascular events, but direct involvement in atherosclerosis remains controversial. Rosuvastatin is a synthetic, hydrophilic statin with unique stereochemistry. A large proportion of patients achieve evidence-based lipid targets while using the drug, and it slows progression and induces regression of atherosclerotic coronary lesions. Rosuvastatin lowers CRP levels significantly. The Justification for Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial was designed after the observation that when both low density lipoprotein and CRP were reduced, patients fared better than when only LDL was lowered. Advocates and critics alike acknowledge that the benefits of rosuvastatin in JUPITER were real. After a review, the US Food and Drug Administration extended the indications for rosuvastatin to include asymptomatic JUPITER-eligible individuals with one additional risk factor. The American Heart Association and Centers of Disease Control and Prevention had previously recognized the use of CRP in persons with "intermediate risk" as defined by global risk scores. The Canadian Cardiovascular Society guidelines went further and recommended use of statins in persons with low LDL and high CRP levels at intermediate risk. The JUPITER study focused attention on ostensibly healthy individuals with

  6. Effects of atorvastatin and rosuvastatin on blood lipids, platelet ...

    African Journals Online (AJOL)

    Conclusion: Atorvastatin and rosuvastatin have no significant effect on the antiplatelet .... J20120006; Astra Zeneca UK limited) 10 mg, .... by Johansen et al [29] and Wang et al [30] .... Pan Y, Chen W, Xu Y, Yi X, Han Y, Yang Q, Li X, Huang.

  7. Efficacy and safety of rosuvastatin every other day compared with once daily in patients with hypercholesterolemia.

    Science.gov (United States)

    Wongwiwatthananukit, Supakit; Sansanayudh, Nakarin; Dhummauppakorn, Rawadee; Kitiyadisai, Chutiporn

    2006-11-01

    Although most patients with hypercholesterolemia require life-long therapy with statins, these drugs are underused due to high costs. Every-other-day therapy could be one strategy to resolve this problem. To compare the efficacy and safety of rosuvastatin 10 mg administered every other day versus once daily. An 8 week, randomized, open-label, parallel trial was conducted at the outpatient department of Phramongkutklao Hospital in Bangkok, Thailand. Eighty patients with primary hypercholesterolemia were equally randomized to receive rosuvastatin 10 mg once daily or every other day; 76 patients completed the study. Laboratory data were assessed at baseline and at the end of the study. Low-density lipoprotein cholesterol (LDL-C) levels were reduced by 48% and 39% in the once-daily and every-other-day groups, respectively (p = 0.011). The percentage of patients who achieved LDL-C goals according to National Cholesterol Education Program-Adult Treatment Panel III guidelines was not significantly different between the once-daily (85%) and every-other-day (70%) groups (p = 0.180). In addition, both regimens were well tolerated, with no patient developing an elevation of more than 3 times baseline levels of aspartate aminotransferase or alanine aminotransferase or 10 times that of creatine kinase. As expected, the monthly cost per percent LDL-C reduction of the once-daily (0.72 dollars) regimen was about 38% higher than that of the every-other-day (0.44 dollars) regimen. Every-other-day dosing of rosuvastatin may be an alternative regimen for cost savings, without a major decrease in therapeutic benefit or increase in adverse events, in patients with hypercholesterolemia. The number of patients achieving their LDL-C goal using the every-other-day regimen is comparable with the number using the once-daily regimen, especially in the low-risk patient category.

  8. Soybean glycinin improves HDL-C and suppresses the effects of rosuvastatin on hypercholesterolemic rats

    Directory of Open Access Journals (Sweden)

    Neves Valdir A

    2011-09-01

    Full Text Available Abstract Background This study was an investigation of the effects of ingesting a daily dose of isolated glycinin soy protein (11S globulin, in association with rosuvastatin, on the control of hypercholesterolemia in experimental animals. Methods Male Wistar rats were kept in individual cages under appropriate controlled conditions of temperature, light and humidity. The animals were divided into five groups (n = 9: 1 standard (STD: fed on casein as protein source; 2 hypercholesterolemic (HC: STD plus 1% cholesterol and 0.5% cholic acid; 3 HC+11S: hypercholesterolemic + glycinin (300 mg/kg/day; 4 HC+ROS: hypercholesterolemic + rosuvastatin (10 mg/kg/day; 5 HC+11S+ROS: HC diet, the 11S protein and the drug in the doses given in (3 and (4. The protein and the drug were administered by gavage for 28 days. The results indicated that the addition of 1% cholesterol and 0.5% cholic acid induced hypercholesterolemia in the animals without interfering with their weight gain. Results A single daily dose of glycinin contributed an additional 2.8% of dietary protein intake and demonstrated its functional role, particularly in raising HDL-C, decreasing triglycerides in the liver and improving the atherogenic index in animals exposed to a hypercholesterolemic diet. Conclusion Most of the beneficial effects of the isolated treatments disappeared when the drug (rosuvastatin and the protein (glycinin were taken simultaneously. The association was shown not to interact additively, as noted in the plasma levels of total cholesterol and non-HDL cholesterol, and in the significant increase of cholesterol in the liver. Studies are in progress to identify the effects of peptides derived from the 11S globulin and their role in cholesterol metabolism.

  9. Clinical utility of rosuvastatin and other statins for cardiovascular risk reduction among the elderly

    Directory of Open Access Journals (Sweden)

    Sydney B Long

    2010-12-01

    Full Text Available Sydney B Long, Michael J Blaha, Roger S Blumenthal, Erin D MichosJohns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USAAbstract: Age is one of the strongest predictors of cardiovascular disease (CVD risk. Treatment with statins can significantly reduce CVD events and mortality in both primary and secondary prevention. Yet despite the high CVD risk among the elderly, there is underutilization of statins in this population (ie, the treatment-risk paradox. Few studies have investigated the use of statins in the elderly, particularly for primary prevention and, as a result, guidelines for treating the elderly are limited. This is likely due to: uncertainties of risk assessment in older individuals where the predictive value of individual risk factors is decreased; the need to balance the benefits of primary prevention with the risks of polypharmacy, health care costs, and adverse medication effects in a population with decreased life expectancy; the complexity of treating patients with many other comorbidities; and increasingly difficult social and economic concerns. As life expectancy increases and the total elderly population grows, these issues become increasingly important. JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin is the largest primary prevention statin trial to date and enrolled a substantial number of elderly adults. Among the 5695 JUPITER participants ≥70 years of age, the absolute CVD risk reduction associated with rosuvastatin was actually greater than for younger participants. The implications of this JUPITER subanalysis and the broader role of statins among older adults is the subject of this review.Keywords: JUPITER, rosuvastatin, elderly, risk

  10. Efficacy of 5MG and 10MG rosuvastatin in type-2 diabetes mellitus with hypercholesteroalemia

    International Nuclear Information System (INIS)

    Ullah, F.; Rahim, F.; Rahman, S.U.; Ashfaq, M.; Afridi, A.K.

    2015-01-01

    Background: Coronary Heart Disease (CHD) is the most important complication and the leading cause of death in patients with type 2 diabetes mellitus (T2DM). Hypercholesterolemia is an important modifiable risk factor for CHD. Statins are the first line drugs for the treatment of hypercholesterolemia in DM. Comparative studies between different statins are available but different doses of the same statin have not been compared in our population. The objective of this study is to compare mean reduction in serum LDL-C level after using 5mg and 10mg of rosuvastatin among T2DM patients with hypercholesterolemia. This study will help finding lowest effective dose of rosuvastatin to achieve internationally set low density lipoprotein cholesterol (LDL-C) goals. Method: A total of 82 patients with T2DM having fasting LDL-C levels equal or more than 100mg/dl were randomly allocated into two groups with 41 patients in each group. Baseline fasting serum LCL-C levels were obtained in all patients. Group A received 5mg while group B received 10mg of rosuvastatin daily at night. After 6 weeks, fasting LDL-C levels were obtained and analysed to compare the mean±SD reduction of LDL-C levels in both groups. Results: Baseline mean±SD LDL-C levels in group A and group B were 134.12±30.02 and 143.49±32.01 respectively (p 0.176). Follow up mean ± SD LDL-C levels were 81.59±28.47 and 83.24±36.06 respectively (p 0.818). Mean ± SD reduction in LDL-C levels from baseline levels in group A and group B were 52.51±19.49 and 60.20±24.09 (p 0.116). Conclusion: Rosuvastatin 5mg is as effective as 10mg in reducing the LDL-C levels in type 2 diabetic patients with hypercholesterolemia. (author)

  11. Biographical encyclopedia of astronomers

    CERN Document Server

    Trimble, Virginia; Williams, Thomas; Bracher, Katherine; Jarrell, Richard; Marché, Jordan; Palmeri, JoAnn; Green, Daniel

    2014-01-01

    The Biographical Encyclopedia of Astronomers is a unique and valuable resource for historians and astronomers alike. It includes approx. 1850 biographical sketches on astronomers from antiquity to modern times. It is the collective work of 430 authors edited by an editorial board of 8 historians and astronomers. This reference provides biographical information on astronomers and cosmologists by utilizing contemporary historical scholarship. The fully corrected and updated second edition adds approximately 300 biographical sketches. Based on ongoing research and feedback from the community, the new entries will fill gaps and provide expansions. In addition, greater emphasis on Russo phone astronomers and radio astronomers is given. Individual entries vary from 100 to 1500 words, including the likes of the super luminaries such as Newton and Einstein, as well as lesser-known astronomers like Galileo's acolyte, Mario Guiducci.

  12. Exotic Molecules in Space: A Coordinated Astronomical Laboratory and Theoretical Study

    Science.gov (United States)

    Stringfellow, Guy (Technical Monitor); Thaddeus, Patrick

    2004-01-01

    The final report covers the two year of a grant which represents a direct continuation of NASA NAG5-4050, with the same title as before. It is dedicated as before to the discovery and characterization of new astrophysical molecules. The four years (two of the original grant plus two years extension) have been extremely productive, yielding many new discoveries of astronomical interest at both radio and optical wavelengths, and the publication or submission of the 49 papers listed below. These articles have appeared or will soon appear in the leading refereed journals of astrophysics, chemical physics, physics, or molecular spectroscopy. One is a major invited review (#27) for Moleculur Physics. One of our other invited reviews published in Spectrochimica Acta in 2001 was recently awarded the Sir Harold Thompson Memorial Award, annually given to the best paper in that journal. Michael McCarthy has recently been awarded the Broida Prize.

  13. Effect of rosuvastatin versus atorvastatin treatment on paraoxonase-1 activity in men with established cardiovascular disease and a low HDL-cholesterol

    NARCIS (Netherlands)

    Bergheanu, S. C.; van Tol, A.; Dallinga-Thie, G. M.; Liem, A.; Dunselman, P. H. J.; van der Bom, J. G.; Jukema, J. W.

    2007-01-01

    Paraoxonase-1 (PON-1) is a high-density lipoprotein (HDL) associated enzyme involved in the protective mechanisms of HDL. Our aim was to compare the effect of treatment with rosuvastatin and atorvastatin on serum PON-1 activity. We performed a prespecified prospective study in 68 patients, part of a

  14. Effect of rosuvastatin versus atorvastatin treatment on paraoxonase-1 activity in men with established cardiovascular disease and a low HDL-cholesterol

    NARCIS (Netherlands)

    Bergheanu, S. C.; van Tol, A.; Dallinga-Thie, G. M.; Liem, A.; Dunselman, P. H. J.; Van Der Bom, J. G.; Jukema, J. W.

    Objective: Paraoxonase-1 (PON-1) is a highdensity lipoprotein (HDL) associated enzyme involved in the protective mechanisms of HDL. Our aim was to compare the effect of treatment with rosuvastatin and atorvastatin on serum PON-1 activity. Methods: We performed a prespecif ied prospective study in 68

  15. Building Blocks of Dust and Large Organic Molecules: a Coordinated Laboratory and Astronomical Study of AGB Stars

    Science.gov (United States)

    McCarthy, Michael C.; Gottlieb, Carl A.; Cernicharo, Jose

    2017-06-01

    The increased sensitivity and angular resolution of high-altitude ground-based interferometers in the sub-millimeter band has enabled the physics and chemistry of carbon- and oxygen-rich evolved stars to be re-examined at an unprecedented level of detail. Observations of rotational lines in the inner envelope - the region within a few stellar radii of the central star where the molecular seeds of dust are formed - allows one to critically assess models of dust growth. Interferometric observations of the outer envelope provide stringent tests of neutral and ionized molecule formation. All of the astronomical studies are crucially dependent on precise laboratory measurements of the rotational spectra of new species and of vibrationally excited levels of known molecules and their rare isotopic species. By means of a closely coordinated laboratory and astronomical program, a number of exotic species including the disilicon carbide SiCSi, titanium oxides TiO and TiO_2, and carbon chain anions ranging from CN^- to C_8H^- have recently been observed in evolved stars. This talk will provide overview of these findings, and how they impact current models of the ``chemical laboratories'' of evolved stars. Ongoing laboratory studies of small silicon-bearing molecules such as H_2SiO_2 and vibrationally excited SiC_2 will be highlighted.

  16. Effect of a single gemfibrozil dose on the pharmacokinetics of rosuvastatin in bile and plasma in healthy volunteers.

    Science.gov (United States)

    Bergman, Ebba; Matsson, Elin M; Hedeland, Mikael; Bondesson, Ulf; Knutson, Lars; Lennernäs, Hans

    2010-09-01

    The effect of a single intrajejunal dose of gemfibrozil (600 mg) on the plasma pharmacokinetics and biliary excretion of a single intrajejunal dose of rosuvastatin (20 mg) was investigated by using a multichannel catheter positioned in the distal duodenum-proximal jejunum in 8 healthy volunteers. Bile and plasma samples were collected every 20 minutes for 200 minutes, with additional plasma samples being drawn for up to 48 hours. Gemfibrozil did not affect the bioavailability of rosuvastatin, although it increased the apparent absorption phase during the initial 200 minutes (AUC(plasma,200min)) by 1.56-fold (95% confidence interval, 1.14-2.15). The interaction was less pronounced in this single-dose study than in a previous report when gemfibrozil was administered repeatedly; nevertheless, the interaction coincided with the highest exposure to gemfibrozil. The plausible reason why the interaction in this investigation was only minor is the low exposure to gemfibrozil (and its metabolites), suggesting that the total plasma concentration of gemfibrozil needs to be above 20 µM to affect the disposition of rosuvastatin. This study demonstrates the value of monitoring the plasma pharmacokinetics of the inhibitor, and not only the drug under investigation, to improve the mechanistic interpretation.

  17. Rosuvastatin and Atorvastatin: Comparative Effects on Glucose Metabolism in Non-Diabetic Patients with Dyslipidaemia

    Directory of Open Access Journals (Sweden)

    Ahmed Abbas

    2012-01-01

    Full Text Available The ever increasing interventional CVD outcome studies have resulted in statins being an essential factor of cardiovascular prevention strategies. The JUPITER study in 2008, despite reducing CVD and overall mortality, highlighted an increase in new onset diabetes in the rosuvastatin treated arm. Since then there have been many meta-analyses of the RCTs and the largest carried out by Sattar et al showed a significant increase in the incidence of diabetes during the trials. The findings from the individual studies when comparing the different statins were less clear. A higher statin dosage and risk factors associated with diabetes appeared to predict this phenomenon. There have been many studies investigating the effects of statins on glycaemic control, but again no clear conclusion is apparent. Despite the increase in new onset diabetes observed, the risk is clearly out-weighed by the CVD benefits observed in nearly all the statin trials. Thus, no change is required to any of the prevention guidelines regarding statins. However, it may be prudent to monitor glycaemic control after commencing statin therapy. This review will focus on atorvastatin which is the most widely used statin worldwide and rosuvastatin which is the most efficacious. This will be against a background of the effects of other statins on glucose metabolism in non-diabetic patients.

  18. Rosuvastatin and atorvastatin: comparative effects on glucose metabolism in non-diabetic patients with dyslipidaemia.

    Science.gov (United States)

    Abbas, Ahmed; Milles, John; Ramachandran, Sudarshan

    2012-01-01

    The ever increasing interventional CVD outcome studies have resulted in statins being an essential factor of cardiovascular prevention strategies. The JUPITER study in 2008, despite reducing CVD and overall mortality, highlighted an increase in new onset diabetes in the rosuvastatin treated arm. Since then there have been many meta-analyses of the RCTs and the largest carried out by Sattar et al showed a significant increase in the incidence of diabetes during the trials. The findings from the individual studies when comparing the different statins were less clear. A higher statin dosage and risk factors associated with diabetes appeared to predict this phenomenon. There have been many studies investigating the effects of statins on glycaemic control, but again no clear conclusion is apparent. Despite the increase in new onset diabetes observed, the risk is clearly out-weighed by the CVD benefits observed in nearly all the statin trials. Thus, no change is required to any of the prevention guidelines regarding statins. However, it may be prudent to monitor glycaemic control after commencing statin therapy. This review will focus on atorvastatin which is the most widely used statin worldwide and rosuvastatin which is the most efficacious. This will be against a background of the effects of other statins on glucose metabolism in non-diabetic patients.

  19. Application of Liquisolid Technology for Enhancing Solubility and Dissolution of Rosuvastatin

    Directory of Open Access Journals (Sweden)

    Pavan Ram Kamble

    2014-03-01

    Full Text Available Purpose: Rosuvastatin is a poorly water soluble drug and the rate of its oral absorption is often controlled by the dissolution rate in the gastrointestinal tract. Hence it is necessary to increase the solubility of the Rosuvastatin. Methods: Several liquisolid tablets formulations containing various drug concentrations in liquid medication (ranging from 15% to 25% w/w were prepared. The ratio of Avicel PH 102 (carrier to Aerosil 200 (coating powder material was kept 10, 20, 30. The prepared liquisolid systems were evaluated for their flow properties and possible drug-excipient interactions by Infrared spectra (IR analysis, differential scanning calorimetry (DSC and X- ray powder diffraction (XRPD. Results: The liquisolid system showed acceptable flow properties. The IR and DSC studies demonstrated that there is no significant interaction between the drug and excipients. The XRPD analysis confirmed formation of a solid solution inside the compact matrix. The tabletting properties of the liquisolid compacts were within the acceptable limits. Liquisolid compacts demonstrated significantly higher drug release rates than those of conventional and marketed tablet due to increasing wetting properties and surface area of the drug. Conclusion: This study shows that liquisolid technique is a promising alternative for improvement of the dissolution rate of water insoluble drug.

  20. Effects of short-term rosuvastatin therapy on heart and kidney function in patients with acute coronary syndrome combining diabetes mellitus and concomitant chronic kidney disease

    Directory of Open Access Journals (Sweden)

    Heng WU

    2014-08-01

    Full Text Available Objective To observe the effects and safety of rosuvastatin therapy on protecting the renal and heart function in patients with acute coronary syndrome (ACS combining diabetes mellitus (DM and concomitant chronic kidney disease (CKD undergoing contrast media injection. Methods Concurrent parallel control and before-after self-control method were employed in present study. From Dec. 2008 to Oct. 2011, 2998 patients from 53 central hospitals in China were enrolled in a TRACK-D project. Out of 2998, 2309 patients with ACS combining DM and concomitant CKD were randomly assigned to rosuvastatin group (n=1183 or control group (n=1126. Patients in rosuvastatin group were given rosuvastatin 10mg/d for five days (two days before and three days post-procedure, while those in control group received no treatment. Isotonic non-ionic contrast medium (iodixanol was used in both groups when angiography, left ventriculography and percutaneous vascular intervention were started. Serum creatinine (Scr, estimated glomerular filtration rate (eGFR and urinary albumin/creatinine ratio (ACR were measured before and 48h, 72h after exposure to contrast medium. A 30-day clinical follow-up was conducted including the evaluation of aggravated heart failure, acute renal failure, dialysis/hemofiltration and all-cause mortality. Results No significant difference existed between the two groups at the preoperative levels of Scr (95.11±23.79μmol/L vs 94.88±20.31μmol/L, P=0.80 and eGFR [73.98±14.52ml/(min.1.73m2 vs 74.10±13.80ml/(min.1.73m2, P=0.85]. The postoperative Scr level showed no significant difference between the two groups (94.87±25.15μmol/L vs 95.74±30.50μmol/L, P=0.45, however, the postoperative Scr value presented a decline tendency in rosuvastatin group, while an upward trend in control group. The 30-day clinical follow-up found that the incidence of aggravated heart failure was significantly lower in rosuvastatin group than in control group (2.4% vs

  1. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis

    DEFF Research Database (Denmark)

    Fellström, Bengt C; Jardine, Alan G; Schmieder, Roland E

    2009-01-01

    . Secondary end points included death from all causes and individual cardiac and vascular events. RESULTS: After 3 months, the mean reduction in low-density lipoprotein (LDL) cholesterol levels was 43% in patients receiving rosuvastatin, from a mean baseline level of 100 mg per deciliter (2.6 mmol per liter......BACKGROUND: Statins reduce the incidence of cardiovascular events in patients at high cardiovascular risk. However, a benefit of statins in such patients who are undergoing hemodialysis has not been proved. METHODS: We conducted an international, multicenter, randomized, double-blind, prospective...... trial involving 2776 patients, 50 to 80 years of age, who were undergoing maintenance hemodialysis. We randomly assigned patients to receive rosuvastatin, 10 mg daily, or placebo. The combined primary end point was death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke...

  2. Facile LC-UV methods for simultaneous monitoring of ciprofloxacin and rosuvastatin in API, formulations and human serum.

    Science.gov (United States)

    Arayne, M Saeed; Sultana, Najma; Tabassum, Arman

    2015-02-01

    An efficient, selective and cost-effective liquid chromatographic assay was developed and validated for the simultaneous quantification of ciprofloxacin and rosuvastatin in Active Pharmaceutical Ingredients (API), pharmaceutical formulations and in human serum. The chromatographic system consisted of mobile phase methanol-water, 90:10 v/v at pH 3.0 adjusted with o-phosphoric acid, pumped at 1.0 mL/min through a prepacked Purospher Star C18 (5 µm, 25 × 0.46 cm) column and effluent was monitored at the isosbestic point (255 nm) as well as at the λmax of individual drugs (243 and 271 nm). The method was validated over a linear concentration range of 0.25-15 µg/mL for ciprofloxacin and 0.33-20 µg/mL for rosuvastatin (r(2)  ≥ 0.999). The ranges of reliable response (limits of detection and quantitation) for ciprofloxacin were 3-15 and 9-45 ng/mL and 17-29 and 52-88 ng/mL, respectively, for rosuvastatin in all API, pharmaceutical formulations and human serum. Analytical recovery from human serum was >98% and relative standard deviation (RSD) was <2. The accuracies were 97.13-102.55 and 97.41-101.31% and precisions in RSD were 0.04-1.90 and 0.02-1.23% for ciprofloxacin and rosuvastatin, respectively. No matrix interferences, ion suppression/enhancement and carry-over were detected. The total assay run time was less than 5 min. In another study, for optimum performance the detector was programmed for multiwavelength scanning at the absorption maxima of each component. Consequently, the linearity range was improved and limit of detection and quantitation values were down to 1-4 and 4-12 ng/mL for ciprofloxacin and 3-5 and 9-15 ng/mL for rosuvastatin, respectively. The validation parameters fitted ICH guidelines through the isosbestic and individual λmax approach. The small sample volume and simplicity of preparation make this method suitable for use in human serum samples, pharmaceutical formulations, quality control, drug

  3. Adding exercise training to rosuvastatin treatment: influence on serum lipids and biomarkers of muscle and liver damage.

    Science.gov (United States)

    Coen, Paul M; Flynn, Michael G; Markofski, Melissa M; Pence, Brandt D; Hannemann, Robert E

    2009-07-01

    Statin treatment and exercise training can improve lipid profile when administered separately. The efficacy of exercise and statin treatment combined, and its impact on myalgia and serum creatine kinase (CK) have not been completely addressed. The purpose of this study was to determine the effect of statin treatment and the addition of exercise training on lipid profile, including oxidized low-density lipoprotein (oxLDL), and levels of CK and alanine transaminase. Thirty-one hypercholesterolemic and physically inactive subjects were randomly assigned to rosuvastatin (R) or rosuvastatin/exercise (RE) group. A third group of physically active hypercholesterolemic subjects served as an active control group (AC). The R and RE groups received rosuvastatin treatment (10 mg/d) for 20 weeks. From week 10 to week 20, the RE group also participated in a combined endurance and resistive exercise training program (3 d/wk). Lipid profile was determined for all subjects at week 0 (Pre), week 10 (Mid), and week 20 (Post). The CK and alanine transaminase levels were measured at the same time points in the RE and R groups and 48 hours after the first and fifth exercise bout in the RE group. Each RE subject was formally queried about muscle fatigue, soreness, and stiffness before each training session. Total, LDL, and oxLDL cholesterol was lower in the RE and R groups at Mid and Post time points when compared with Pre. Oxidized LDL was lower in the RE group compared with the R group at the Post time point. When treatment groups (R and RE) were combined, high-density lipoprotein levels were increased and triglycerides decreased across time. Creatine kinase increased in the RE group 48 hours after the first exercise bout, but returned to baseline levels 48 hours after the fifth exercise bout. Rosuvastatin treatment decreased total, LDL, and oxLDL cholesterol. The addition of an exercise training program resulted in a further decrease in oxLDL. There was no abnormal sustained increase

  4. Effects of intensive atorvastatin and rosuvastatin treatment on apolipoprotein B-48 and remnant lipoprotein cholesterol levels

    Science.gov (United States)

    Atorvastatin and rosuvastatin at maximal doses are both highly effective in lowering low-density lipoprotein cholesterol (LDL-C) and triglyceride (TG) levels. Rosuvastatin has been shown to be more effective than atorvastatin in lowering LDL-C, small dense LDL-C and in raising high-density lipoprote...

  5. Grigor Narekatsi's astronomical insights

    Science.gov (United States)

    Poghosyan, Samvel

    2015-07-01

    What stand out in the solid system of Gr. Narekatsi's naturalistic views are his astronomical insights on the material nature of light, its high speed and the Sun being composed of "material air". Especially surprising and fascinating are his views on stars and their clusters. What astronomers, including great Armenian academician V. Ambartsumian (scattering of stellar associations), would understand and prove with much difficulty thousand years later, Narekatsi predicted in the 10th century: "Stars appear and disappear untimely", "You who gather and scatter the speechless constellations, like a flock of sheep". Gr. Narekatsti's reformative views were manifested in all the spheres of the 10th century social life; he is a reformer of church life, great language constructor, innovator in literature and music, freethinker in philosophy and science. His ideology is the reflection of the 10th century Armenian Renaissance. During the 9th-10th centuries, great masses of Armenians, forced to migrate to the Balkans, took with them and spread reformative ideas. The forefather of the western science, which originated in the period of Reformation, is considered to be the great philosopher Nicholas of Cusa. The study of Gr. Narekatsti's logic and naturalistic views enables us to claim that Gr. Narekatsti is the great grandfather of European science.

  6. The South African Astronomical Observatory

    International Nuclear Information System (INIS)

    1989-01-01

    The research work discussed in this report covers a wide range, from work on the nearest stars to studies of the distant quasars, and the astronomers who have carried out this work come from universities and observatories spread around the world as well as from South African universities and from the South African Astronomical Observatory (SAAO) staff itself. A characteristic of much of this work has been its collaborative character. SAAO studies in 1989 included: supernovae 1987A; galaxies; ground-based observations of celestial x-ray sources; the Magellanic Clouds; pulsating variables; galactic structure; binary star phenomena; the provision of photometric standards; nebulous matter; stellar astrophysics, and astrometry

  7. The Practical Astronomer

    Science.gov (United States)

    Koester, Jack

    "The Practical Astronomer" by Thomas Dick, LLD, E.C. & J. Biddle, Philadelphia, 1849, is reviewed. Information on telescope makers and astronomers can be found. Mentioned are: Fraunhofer; John Herschel; Lawson; Dollond; Tulley; W. & S. Jones; and S.W. Burnham.

  8. WWC Review of the Report "Conceptualizing Astronomical Scale: Virtual Simulations on Handheld Tablet Computers Reverse Misconceptions." What Works Clearinghouse Single Study Review

    Science.gov (United States)

    What Works Clearinghouse, 2014

    2014-01-01

    The 2014 study, "Conceptualizing Astronomical Scale: Virtual Simulations on Handheld Tablet Computers Reverse Misconceptions," examined the effects of using the true-to-scale (TTS) display mode versus the orrery display mode in the iPad's Solar Walk software application on students' knowledge of the Earth's place in the solar system. The…

  9. Pharmacokinetic interactions between glimepiride and rosuvastatin in healthy Korean subjects: does the SLCO1B1 or CYP2C9 genetic polymorphism affect these drug interactions?

    Directory of Open Access Journals (Sweden)

    Kim CO

    2017-02-01

    Full Text Available Choon Ok Kim,1 Eun Sil Oh,2 Hohyun Kim,3 Min Soo Park1,4 1Department of Clinical Pharmacology, Severance Hospital, Yonsei University College of Medicine, Seoul, 2Department of Pharmaceutical Medicine and Regulatory Sciences, College of Medicine and Pharmacy, Yonsei University, Incheon, 3Korea Medicine Research Institute, Inc., Seongnam, 4Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea Abstract: To improve cardiovascular outcomes, dyslipidemia in patients with diabetes needs to be treated. Thus, these patients are likely to take glimepiride and rosuvastatin concomitantly. Therefore, this study aimed to evaluate the pharmacokinetic (PK interactions between these two drugs in healthy males and to explore the effect of SLCO1B1 and CYP2C9 polymorphisms on their interactions in two randomized, open-label crossover studies. Glimepiride was studied in part 1 and rosuvastatin in part 2. Twenty-four participants were randomly assigned to each part. All subjects (n=24 completed part 1, and 22 subjects completed part 2. A total of 38 subjects among the participants of the PK interaction studies were enrolled in the genotype study to analyze their SLCO1B1 and CYP2C9 polymorphisms retrospectively (n=22 in part 1, n=16 in part 2. Comparison of the PK and safety of each drug alone with those of the drugs in combination showed that both glimepiride and rosuvastatin did not interact with each other and had tolerable safety profiles in all subjects. However, with regard to glimepiride PK, the SLCO1B1 521TC group had a significantly higher maximum plasma concentration (Cmax,ss and area under the plasma concentration–time curve during the dose interval at steady state (AUCt,ss for glimepiride in combination with rosuvastatin than those for glimepiride alone. However, other significant effects of the SLCO1B1 or CYP2C9 polymorphism on the interaction between the two drugs were not observed. In conclusion, there were no significant PK

  10. Analytical Methods for the Determination of Rosuvastatin in Pharmaceutical Formulations and Biological Fluids: A Critical Review.

    Science.gov (United States)

    Ângelo, Marilene Lopes; Moreira, Fernanda de Lima; Morais Ruela, André Luís; Santos, Ana Laura Araújo; Salgado, Hérida Regina Nunes; de Araújo, Magali Benjamim

    2018-07-04

    Rosuvastatin calcium (ROS), ( Figure 1 ) belongs to the "statins" group, which is the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. This drug is indicated for dyslipidemias treatment and can help to decrease the level of "bad cholesterol" and can consequently reduce the development of atherosclerosis and the risk of heart diseases. ROS was developed by Astra-Zeneca and it was approved in 2003 by the FDA in the United States. In 2015, under the trade name Crestor®, it was the fourth largest selling drug in the United States with sales above $5 billion. This study presents a literature review of analytical methods for the quantification of ROS in pharmaceutical preparations and biological fluids. The major analytical methods described in this study for ROS were spectrophotometry, high-performance liquid chromatography (HPLC) coupled to ultraviolet (UV) detection, and tandem mass spectrometry (LC-MS/MS).

  11. UKRVO Astronomical WEB Services

    Directory of Open Access Journals (Sweden)

    Mazhaev, O.E.

    2017-01-01

    Full Text Available Ukraine Virtual Observatory (UkrVO has been a member of the International Virtual Observatory Alliance (IVOA since 2011. The virtual observatory (VO is not a magic solution to all problems of data storing and processing, but it provides certain standards for building infrastructure of astronomical data center. The astronomical databases help data mining and offer to users an easy access to observation metadata, images within celestial sphere and results of image processing. The astronomical web services (AWS of UkrVO give to users handy tools for data selection from large astronomical catalogues for a relatively small region of interest in the sky. Examples of the AWS usage are showed.

  12. An astronomical murder?

    Science.gov (United States)

    Belenkiy, Ari

    2010-04-01

    Ari Belenkiy examines the murder of Hypatia of Alexandria, wondering whether problems with astronomical observations and the date of Easter led to her becoming a casualty of fifth-century political intrigue.

  13. The amateur astronomer

    CERN Document Server

    Moore, Patrick

    2006-01-01

    Introduces astronomy and amateur observing together. This edition includes photographs and illustrations. The comprehensive appendices provide hints and tips, as well as data for every aspect of amateur astronomy. This work is useful for amateur astronomers

  14. Astronomical References in Chaucer: What Can Modern Students Learn from Studying Ancient Texts?

    Directory of Open Access Journals (Sweden)

    Victor Kennedy

    2005-06-01

    Full Text Available One of the problems in the field of English literature studies is that, with compartmentalization and specialization, it becomes introspective to the point where it devolves into the study of metafiction and metacriticism. At its heart, however, literature has to be about something: Thackeray claimed its subject is human nature, but human nature is based in the interface between human and nature. This paper explores some of the problems in the interface between human knowledge, institutions, and nature, and will offer an example of cross-disciplinary, historical study to illustrate a well-known but, to most modern readers, impenetrable medieval text, Chaucer’s Treatise on the Astrolabe. It ends with three recommendations: look to history, cross boundaries between academic fields, and use practical, as well as theoretical, teaching methods.

  15. Construction of the iSTAR international Study of Astronomical Reasoning Database

    Science.gov (United States)

    Slater, S. J.; Tatge, C. B.; Slater, T. F.; Bretones, P. S.; Schleigh, S.

    2016-12-01

    Perhaps more than any other science discipline-based education research field, the scholarly literature base describing and documenting astronomy education research is highly fragmented and widely dispersed across numerous journals. The resulting wide diversity of journals that publish astronomy education research presents an arduous challenge for scholars trying to best understand what work has been done and what work still needs to be done. Moreover, a vast amount of education research on the teaching and learning of astronomy exists in dissertations that were never published and even more exists in the realm of un-disseminated grey literature hosted in conference proceedings and society newsletters going back decades. With a few notable exceptions far less extensive than the current project, there has been no comprehensive repository for cataloging astronomy education research methods and results to date. In response, an international cadre of scholars coordinated by the CAPER Center for Astronomy & Physics Education Research are creating the underlying structure for an online database in order to conduct an international Study of Astronomy Reasoning, iSTAR, project. The online iSTAR database serves as an online host to bring together in one place digital copies of hard to locate journal articles, isolated dissertations and theses, and professional meeting contributions to extend the world's scholars abilities to more easily find and utilize a far broader collection of astronomy education research literature than has been previously available. Works are categorized by research method, nature of study-participants, educational learning venue studied, country and language of the study, and other fruitfully useful categories. Scholars wishing to add their own literature resources are encouraged to contribute to the online database located at istardatabase.org

  16. Studies in astronomical time series analysis. I - Modeling random processes in the time domain

    Science.gov (United States)

    Scargle, J. D.

    1981-01-01

    Several random process models in the time domain are defined and discussed. Attention is given to the moving average model, the autoregressive model, and relationships between and combinations of these models. Consideration is then given to methods for investigating pulse structure, procedures of model construction, computational methods, and numerical experiments. A FORTRAN algorithm of time series analysis has been developed which is relatively stable numerically. Results of test cases are given to study the effect of adding noise and of different distributions for the pulse amplitudes. A preliminary analysis of the light curve of the quasar 3C 272 is considered as an example.

  17. Intensive lipid-lowering therapy with rosuvastatin stabilizes lipid-rich coronary plaques. Evaluation using dual-source computed tomography

    International Nuclear Information System (INIS)

    Soeda, Tsunenari; Uemura, Shiro; Okayama, Satoshi

    2011-01-01

    Clinical studies using invasive modalities have reported that statin therapy stabilizes coronary plaque vulnerability. The serial changes of lipid-rich coronary plaques (LRCPs) during rosuvastatin treatment were evaluated non-invasively in patients with acute coronary syndrome (ACS) using dual-source computed tomography (DSCT). A total of 11 consecutive ACS patients, and 13 LRCPs were serially evaluated on DSCT before and 24 weeks after rosuvastatin treatment. Compared with the baseline, there was no change in post-treatment minimal lumen diameter, lumen volume, or longitudinal length of LRCPs. By contrast, the ratio of lipid core volume to plaque volume significantly decreased from 48.0±9.9% to 43.7±10.6% (P=0.04), and plaque volume decreased from 144.5±85.5 mm 3 to 119.8±78.0 mm 3 (P=0.07). The remodeling index of target LRCPs significantly decreased from 1.16±0.10 to 1.06±0.12 (P=0.02). Percent reduction of plaque volume was significantly greater in patients with a lower ratio of low-density lipoprotein to high-density lipoprotein (L/H ratio ≤1.5) at follow-up than patients with higher L/H ratio (>1.5; median -31.7% vs. -6.8%, P=0.03). Rosuvastatin therapy reduced the volume of lipid cores and LRCPs and increased the CT attenuation value of LRCPs. DSCT is an effective modality for the non-invasive evaluation of LRCPs in patients with ACS. (author)

  18. Studies in astronomical time series analysis: Modeling random processes in the time domain

    Science.gov (United States)

    Scargle, J. D.

    1979-01-01

    Random process models phased in the time domain are used to analyze astrophysical time series data produced by random processes. A moving average (MA) model represents the data as a sequence of pulses occurring randomly in time, with random amplitudes. An autoregressive (AR) model represents the correlations in the process in terms of a linear function of past values. The best AR model is determined from sampled data and transformed to an MA for interpretation. The randomness of the pulse amplitudes is maximized by a FORTRAN algorithm which is relatively stable numerically. Results of test cases are given to study the effects of adding noise and of different distributions for the pulse amplitudes. A preliminary analysis of the optical light curve of the quasar 3C 273 is given.

  19. Study of the unknown hemisphere of mercury by ground-based astronomical facilities

    Science.gov (United States)

    Ksanfomality, L. V.

    2011-08-01

    The short exposure method proved to be very productive in ground-based observations of Mercury. Telescopic observations with short exposures, together with computer codes for the processing of data arrays of many thousands of original electronic photos, make it possible to improve the resolution of images from ground-based instruments to almost the diffraction limit. The resulting composite images are comparable with images from spacecrafts approaching from a distance of about 1 million km. This paper presents images of the hemisphere of Mercury in longitude sectors 90°-180°W, 215°-350°W, and 50°-90°W, including, among others, areas not covered by spacecraft cameras. For the first time a giant S basin was discovered in the sector of longitudes 250°-290°W, which is the largest formation of this type on terrestrial planets. Mercury has a strong phase effects. As a result, the view of the surface changes completely with the change in the planetary phase. But the choice of the phase in the study using spacecrafts is limited by orbital characteristics of the mission. Thus, ground-based observations of the planet provide a valuable support.

  20. Astronomical Research Institute Photometric Results

    Science.gov (United States)

    Linder, Tyler R.; Sampson, Ryan; Holmes, Robert

    2013-01-01

    The Astronomical Research Institute (ARI) conducts astrometric and photometric studies of asteroids with a concentration on near-Earth objects (NEOs). A 0.76-m autoscope was used for photometric studies of seven asteroids of which two were main-belt targets and five were NEOs, including one potentially hazardous asteroid (PHA). These objects are: 3122 Florence, 3960 Chaliubieju, 5143 Heracles, (6455) 1992 HE, (36284) 2000 DM8, (62128) 2000 SO1, and 2010 LF86.

  1. Neuro, cardio, and reno protective activities of rosuvastatin in streptozotocin-induced type 2 diabetic rats undergoing treatment with metformin and glimepiride

    Directory of Open Access Journals (Sweden)

    Shailaja Rondi

    2014-01-01

    Full Text Available Diabetes is associated with complications like neuropathy, nephropathy, cardiomyopathy, and retinopathy due to increased oxidative stress and serum lipids. In the present study, rosuvastatin, a HMG-CoA inhibitor, was investigated for its protective effect in neuropathy, nephropathy, and cardiomyopathy based on the lipid-lowering property along with its pleiotropic effects such as improved blood flow to the organ and antioxidant defense. Type 2 diabetes was induced in Wistar rats by single i.p. administration of streptozotocin (50 mg/kg. These diabetic rats were treated with daily doses of rosuvastatin (10 mg/kg alone, metformin (120 mg/kg and glimepiride (1 mg/kg and rosuvastatin in combination with metformin (120 mg/kg and glimepiride (1 mg/kg for a period of 6 weeks. The biochemical parameters involved in neuropathy, renopathy, and cardiopathy were estimated. Treatment resulted in significant (P < 0.05 decrease in thiobarbituric acid reactive substances (TBARS and increase in levels of glutathione peroxidise and catalase in brain and kidney homogenates. Significant (P < 0.05 increase in high-density lipoproteins and decrease in creatinine kinase, triglycerides, total serum cholesterol represents the cardioprotective action, whereas significant (P < 0.05 increase in the latency in the hotplate model shows the neuroprotective activity, and significant (P < 0.05 decrease in blood urea nitrogen, creatinine levels and increase in serum total protein levels suggested the renoprotective actions. The unique properties of rosuvastatin such as antioxidant defense and lipid-lowering nature might have resulted in cardio, neuro, and renoprotective activity in type 2 diabetic rats treated with metformin and glimepiride.

  2. Atlas of Astronomical Discoveries

    CERN Document Server

    Schilling, Govert

    2011-01-01

    Four hundred years ago in Middelburg, in the Netherlands, the telescope was invented. The invention unleashed a revolution in the exploration of the universe. Galileo Galilei discovered mountains on the Moon, spots on the Sun, and moons around Jupiter. Christiaan Huygens saw details on Mars and rings around Saturn. William Herschel discovered a new planet and mapped binary stars and nebulae. Other astronomers determined the distances to stars, unraveled the structure of the Milky Way, and discovered the expansion of the universe. And, as telescopes became bigger and more powerful, astronomers delved deeper into the mysteries of the cosmos. In his Atlas of Astronomical Discoveries, astronomy journalist Govert Schilling tells the story of 400 years of telescopic astronomy. He looks at the 100 most important discoveries since the invention of the telescope. In his direct and accessible style, the author takes his readers on an exciting journey encompassing the highlights of four centuries of astronomy. Spectacul...

  3. The South African Astronomical Observatory

    International Nuclear Information System (INIS)

    1988-01-01

    The geographical position, climate and equipment at the South African Astronomical Observatory (SAAO), together with the enthusiasm and efforts of SAAO scientific and technical staff and of visiting scientists, have enabled the Observatory to make a major contribution to the fields of astrophysics and cosmology. During 1987 the SAAO has been involved in studies of the following: supernovae; galaxies, including Seyfert galaxies; celestial x-ray sources; magellanic clouds; pulsating variables; galatic structure; binary star phenomena; nebulae; interstellar matter and stellar astrophysics

  4. Methods in Astronomical Image Processing

    Science.gov (United States)

    Jörsäter, S.

    A Brief Introductory Note History of Astronomical Imaging Astronomical Image Data Images in Various Formats Digitized Image Data Digital Image Data Philosophy of Astronomical Image Processing Properties of Digital Astronomical Images Human Image Processing Astronomical vs. Computer Science Image Processing Basic Tools of Astronomical Image Processing Display Applications Calibration of Intensity Scales Calibration of Length Scales Image Re-shaping Feature Enhancement Noise Suppression Noise and Error Analysis Image Processing Packages: Design of AIPS and MIDAS AIPS MIDAS Reduction of CCD Data Bias Subtraction Clipping Preflash Subtraction Dark Subtraction Flat Fielding Sky Subtraction Extinction Correction Deconvolution Methods Rebinning/Combining Summary and Prospects for the Future

  5. Insights for Planetarium and Museum Educators Revealed by the iSTAR international Study of Astronomical Reasoning Database

    Science.gov (United States)

    Slater, T. F.; Tatge, C. B.; Ratcliff, M.; Slater, S. J.

    2016-12-01

    Dedicated sky watchers through the centuries have long sought to find the best teaching methods to efficiently and effectively transfer vast amounts of accumulated star knowledge to the next generation of sky watchers. Although detailed maps specifying the names and locations of stars have been carefully displayed on spherical globes for thousands of years, it is the 1923 installation of a Zeiss-made, large, mechanical star projector in Munich that is often cited as the first modern projection planetarium for teaching astronomy. In the 1930's, impressive planetariums were installed Chicago, Los Angeles and New York, which then in turn served as a catalyst for additional planetarium construction. Planetarium construction increased rapidly in the United States due to federal funding to schools and museums through the 1958 US National Defense Education Act and the US went from one planetarium in 1930, to six in 1940, to about 100 in 1960, increasing to 200 in 1963, 450 by 1967—even before humans had landed on the Moon—and more than 1,000 by 1975. Today, nearly 3,000 permanent planetarium facilities are available to show the stars and heavenly motions to children and adults alike across the world, with perhaps another thousand portable planetariums adding to the available teaching venues. Simultaneous with their construction, discipline-based astronomy education have been trying to better understand, and ultimately improve, how people learn astronomy in the planetarium. A systematic analysis of planetarium education research articles, dissertations, and theses found in the recently constructed, community-wide, international Study of Astronomical Reasoning iSTAR database at istardatabase.org reveal that many of the systematic studies conducted in the 1960s and 1970s using domes served by servo-mechanical star projects have been reproduced again in recent decades in theaters using digital video projection showing nearly the same results: student-passive, information

  6. Astronomical publications of Melbourne Observatory

    Science.gov (United States)

    Andropoulos, Jenny Ioanna

    2014-05-01

    During the second half of the 19th century and the first half of the 20th century, four well-equipped government observatories were maintained in Australia - in Melbourne, Sydney, Adelaide and Perth. These institutions conducted astronomical observations, often in the course of providing a local time service, and they also collected and collated meteorological data. As well, some of these observatories were involved at times in geodetic surveying, geomagnetic recording, gravity measurements, seismology, tide recording and physical standards, so the term "observatory" was being used in a rather broad sense! Despite the international renown that once applied to Williamstown and Melbourne Observatories, relatively little has been written by modern-day scholars about astronomical activities at these observatories. This research is intended to rectify this situation to some extent by gathering, cataloguing and analysing the published astronomical output of the two Observatories to see what contributions they made to science and society. It also compares their contributions with those of Sydney, Adelaide and Perth Observatories. Overall, Williamstown and Melbourne Observatories produced a prodigious amount of material on astronomy in scientific and technical journals, in reports and in newspapers. The other observatories more or less did likewise, so no observatory of those studied markedly outperformed the others in the long term, especially when account is taken of their relative resourcing in staff and equipment.

  7. ASURV: Astronomical SURVival Statistics

    Science.gov (United States)

    Feigelson, E. D.; Nelson, P. I.; Isobe, T.; LaValley, M.

    2014-06-01

    ASURV (Astronomical SURVival Statistics) provides astronomy survival analysis for right- and left-censored data including the maximum-likelihood Kaplan-Meier estimator and several univariate two-sample tests, bivariate correlation measures, and linear regressions. ASURV is written in FORTRAN 77, and is stand-alone and does not call any specialized libraries.

  8. Information seeking behavior of Greek astronomers

    OpenAIRE

    Brindesi, Hara; Kapidakis, Sarantos

    2011-01-01

    This study examines three aspects of information seeking behaviour of astronomers in Greece including a) the importance they place in keeping up- to-date with current developments b) the methods they depend on for keeping up-to-date and c) the information sources they mostly use. We adopted an intradisciplinary approach in order to investigate similarities and differences in information seeking behaviour among astronomers when examining them as groups bearing different characteristics, includ...

  9. Basic Optics for the Astronomical Sciences

    CERN Document Server

    Breckinridge, James

    2012-01-01

    This text was written to provide students of astronomy and engineers an understanding of optical science - the study of the generation, propagation, control, and measurement of optical radiation - as it applies to telescopes and instruments for astronomical research in the areas of astrophysics, astrometry, exoplanet characterization, and planetary science. The book provides an overview of the elements of optical design and physical optics within the framework of the needs of the astronomical community.

  10. Emulsifying Formulation of Rosuvastatin Calcium for Improved ...

    African Journals Online (AJOL)

    solubility study, liquid formulations were prepared using LAS/Capryol 90: Maisine 35-1 as oil phase and. Tween 20 with ... evaluated for globule size, zeta potential, and emulsion properties. ..... surfactants which decreases the electrostatic.

  11. Possible effects of rosuvastatin on noise-induced oxidative stress in rat brain

    Directory of Open Access Journals (Sweden)

    Alevtina Ersoy

    2014-01-01

    Full Text Available The problem of noise has recently gained more attention as it has become an integral part of our daily lives. However, its influence has yet to be fully elucidated. Other than being an unpleasant stimulus, noise may cause health disorders through annoyance and stress, including oxidative stress. Rosuvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, may possess antioxidant properties. Based on rat models, our project investigates the effect of rosuvastatin on noise-induced oxidative stress in the brain tissue. Thirty-two male Wistar albino rats were used. The rats were divided into four groups: Noise exposure plus rosuvastatin usage, only noise exposure, only rosuvastatin usage, and control. After the data had been collected, oxidant and antioxidant parameters were analyzed in the cerebral cortex, brain stem, and cerebellum. Results indicated that superoxide dismutase values were significantly decreased in the cerebral cortex, while malondialdehyde values in the brainstem and cerebellum were significantly increased in the group with only noise exposure. Superoxide dismutase values in the brainstem were significantly increased, but nitric oxide values in the cerebellum and brainstem and malondialdehyde values in the cerebellum and cerebral cortex were significantly decreased in the group where only rosuvastatin was used. During noise exposure, the use of rosuvastatin caused significantly increased superoxide dismutase values in the cerebral cortex and brainstem, but significantly reduced malondialdehyde values in the brain stem. Consequently, our data show that brain tissue was affected by oxidative stress due to continued exposure to noise. This noise-induced stress decreases with rosuvastatin therapy.

  12. Rosuvastatin reduces atherosclerotic lesions and promotes progenitor cell mobilisation and recruitment in apolipoprotein E knockout mice.

    Science.gov (United States)

    Schroeter, Marco R; Humboldt, Tim; Schäfer, Katrin; Konstantinides, Stavros

    2009-07-01

    Statins enhance incorporation of bone marrow-derived cells into experimental neointimal lesions. However, the contribution of progenitor cells to progression of spontaneous atherosclerotic plaques, and the possible modulatory role of statins in this process, remain poorly understood. We compared the effects of rosuvastatin (1 and 10mg/kg BW) and pravastatin (10mg/kg) on progenitor cell mobilisation, recruitment into atherosclerotic plaques, and lesion growth. Statins were administered over 8 weeks to apolipoprotein E knockout mice on atherogenic diet. In addition, mice were lethally irradiated, followed by transplantation of bone marrow from LacZ transgenic mice. Rosuvastatin reduced lesion area and intima-to-media ratio at the brachiocephalic artery compared to vehicle, while both parameters were not significantly altered by pravastatin. Rosuvastatin also augmented endothelialisation (P<0.05) and reduced the smooth muscle cells (SMC) content (P=0.042) of lesions. Numbers of c-kit, sca-1 and flk-1, sca-1 double-positive progenitor cells were significantly increased in rosuvastatin compared to control-treated mice, both in the bone marrow and the peripheral blood. Similarly, the number of spleen-derived acLDL, lectin double-positive progenitor cells (P=0.001) and colony-forming units (P=0.0104) was significantly increased in mice treated with rosuvastatin compared to vehicle alone. In the bone marrow, increased Akt and p42/44 MAP kinase phosphorylation and upregulated SDF1alpha mRNA expression were observed. Importantly, rosuvastatin treatment also increased the plasma levels of c-kit ligand (P=0.003), and the number of c-kit-positive cells within atherosclerotic lesions (P=0.041). Our findings suggest that rosuvastatin reduces the size of atherosclerotic plaques, and this effect appears to involve progenitor cell mobilisation and recruitment into vascular lesions.

  13. A mechanistic framework for in vitro-in vivo extrapolation of liver membrane transporters: prediction of drug-drug interaction between rosuvastatin and cyclosporine.

    Science.gov (United States)

    Jamei, M; Bajot, F; Neuhoff, S; Barter, Z; Yang, J; Rostami-Hodjegan, A; Rowland-Yeo, K

    2014-01-01

    The interplay between liver metabolising enzymes and transporters is a complex process involving system-related parameters such as liver blood perfusion as well as drug attributes including protein and lipid binding, ionisation, relative magnitude of passive and active permeation. Metabolism- and/or transporter-mediated drug-drug interactions (mDDIs and tDDIs) add to the complexity of this interplay. Thus, gaining meaningful insight into the impact of each element on the disposition of a drug and accurately predicting drug-drug interactions becomes very challenging. To address this, an in vitro-in vivo extrapolation (IVIVE)-linked mechanistic physiologically based pharmacokinetic (PBPK) framework for modelling liver transporters and their interplay with liver metabolising enzymes has been developed and implemented within the Simcyp Simulator(®). In this article an IVIVE technique for liver transporters is described and a full-body PBPK model is developed. Passive and active (saturable) transport at both liver sinusoidal and canalicular membranes are accounted for and the impact of binding and ionisation processes is considered. The model also accommodates tDDIs involving inhibition of multiple transporters. Integrating prior in vitro information on the metabolism and transporter kinetics of rosuvastatin (organic-anion transporting polypeptides OATP1B1, OAT1B3 and OATP2B1, sodium-dependent taurocholate co-transporting polypeptide [NTCP] and breast cancer resistance protein [BCRP]) with one clinical dataset, the PBPK model was used to simulate the drug disposition of rosuvastatin for 11 reported studies that had not been used for development of the rosuvastatin model. The simulated area under the plasma concentration-time curve (AUC), maximum concentration (C max) and the time to reach C max (t max) values of rosuvastatin over the dose range of 10-80 mg, were within 2-fold of the observed data. Subsequently, the validated model was used to investigate the impact of

  14. Effects of maximal doses of atorvastatin versus rosuvastatin on small dense low-density lipoprotein cholesterol levels

    Science.gov (United States)

    Maximal doses of atorvastatin and rosuvastatin are highly effective in lowering low-density lipoprotein (LDL) cholesterol and triglyceride levels; however, rosuvastatin has been shown to be significantly more effective than atorvastatin in lowering LDL cholesterol and in increasing high-density lipo...

  15. Astronomical Spectroscopy for Amateurs

    CERN Document Server

    Harrison, Ken M

    2011-01-01

    Astronomical Spectroscopy for Amateurs is a complete guide for amateur astronomers who are looking for a new challenge beyond astrophotography. The book provides a brief overview of the history and development of the spectroscope, then a short introduction to the theory of stellar spectra, including details on the necessary reference spectra required for instrument testing and spectral comparison. The various types of spectroscopes available to the amateur are then described. Later sections cover all aspects of setting up and using various types of commercially available and home-built spectroscopes, starting with basic transmission gratings and going through more complex models, all the way to the sophisticated Littrow design. The final part of the text is about practical spectroscope design and construction. This book uniquely brings together a collection of observing, analyzing, and processing hints and tips that will allow the amateur to build skills in preparing scientifically acceptable spectra data. It...

  16. Astronomical Research Using Virtual Observatories

    Directory of Open Access Journals (Sweden)

    M Tanaka

    2010-01-01

    Full Text Available The Virtual Observatory (VO for Astronomy is a framework that empowers astronomical research by providing standard methods to find, access, and utilize astronomical data archives distributed around the world. VO projects in the world have been strenuously developing VO software tools and/or portal systems. Interoperability among VO projects has been achieved with the VO standard protocols defined by the International Virtual Observatory Alliance (IVOA. As a result, VO technologies are now used in obtaining astronomical research results from a huge amount of data. We describe typical examples of astronomical research enabled by the astronomical VO, and describe how the VO technologies are used in the research.

  17. Effect of rosuvastatin monotherapy and in combination with fenofibrate or omega-3 fatty acids on serum vitamin D levels.

    Science.gov (United States)

    Makariou, Stefania E; Liberopoulos, Evangelos N; Agouridis, Aris P; Challa, Anna; Elisaf, Moses

    2012-12-01

    Low levels of 25(OH) vitamin D [25(OH)VitD] have been recognized as a new cardiovascular disease (CVD) risk factor. Statins seem to increase 25(OH)VitD concentration. To investigate whether combined treatment with the usual dose of rosuvastatin plus fenofibrate or omega-3 fatty acids would increase 25(OH)VitD levels compared with the high-dose rosuvastatin monotherapy in participants with mixed dislipidemia. We randomly allocated 60 patients with mixed dyslipidemia (low-density lipoprotein cholesterol: >160 mg/dL plus triglycerides: >200 mg/dL) to receive rosuvastatin 40 mg (n = 22), rosuvastatin 10 mg plus fenofibrate 200 mg (n = 21), or rosuvastatin 10 mg plus omega-3 fatty acids 2 g (n = 17) daily for 3 months. Our primary end point was changes in the levels of serum 25(OH)VitD. Rosuvastatin monotherapy was associated with a 53% increase in 25(OH)VitD (from 14.6 [1.0-38.0] to 17.8 [5.3-49.6] ng/mL; P = .000). Rosuvastatin plus micronized fenofibrate and rosuvastatin plus omega-3 fatty acids were associated with increases of 64% (from 14.1 [1.0-48.0] to 18.4 [6.7-52.4] ng/mL, P = .001) and 61% (from 10.4 [6.6-38.4] to 14.0 [9.6-37.6] ng/mL, P = .04), respectively. The changes in 25(OH)VitD after treatment were comparable in the 3 groups. High-dose rosuvastatin monotherapy and the usual dose of rosuvastatin plus fenofibrate or omega-3 fatty acids are associated with significant and similar increases in the 25(OH)VitD levels. This increase may be relevant in terms of CVD risk prevention.

  18. The New Amateur Astronomer

    Science.gov (United States)

    Mobberley, Martin

    Amateur astronomy has changed beyond recognition in less than two decades. The reason is, of course, technology. Affordable high-quality telescopes, computer-controlled 'go to' mountings, autoguiders, CCD cameras, video, and (as always) computers and the Internet, are just a few of the advances that have revolutionized astronomy for the twenty-first century. Martin Mobberley first looks at the basics before going into an in-depth study of what’s available commercially. He then moves on to the revolutionary possibilities that are open to amateurs, from imaging, through spectroscopy and photometry, to patrolling for near-earth objects - the search for comets and asteroids that may come close to, or even hit, the earth. The New Amateur Astronomer is a road map of the new astronomy, equally suitable for newcomers who want an introduction, or old hands who need to keep abreast of innovations. From the reviews: "This is one of several dozen books in Patrick Moore's "Practical Astronomy" series. Amid this large family, Mobberley finds his niche: the beginning high-tech amateur. The book's first half discusses equipment: computer-driven telescopes, CCD cameras, imaging processing software, etc. This market is changing every bit as rapidly as the computer world, so these details will be current for only a year or two. The rest of the book offers an overview of scientific projects that serious amateurs are carrying out these days. Throughout, basic formulas and technical terms are provided as needed, without formal derivations. An appendix with useful references and Web sites is also included. Readers will need more than this book if they are considering a plunge into high-tech amateur astronomy, but it certainly will whet their appetites. Mobberley's most valuable advice will save the book's owner many times its cover price: buy a quality telescope from a reputable dealer and install it in a simple shelter so it can be used with as little set-up time as possible. A poor

  19. On astronomical drawing [1846

    Science.gov (United States)

    Smyth, Charles Piazzi

    Reprinted from the Memoirs of the Royal Astronomical Society 15, 1846, pp. 71-82. With annotations and illustrations added by Klaus Hentschel. The activities of the Astronomer Royal for Scotland, Charles Piazzi Smyth (1819-1900), include the triangulation of South African districts, landscape painting, day-to-day or tourist sketching, the engraving and lithographing of prominent architectural sites, the documentary photography of the Egyptian pyramids or the Tenerife Dragon tree, and `instant photographs' of the clouds above his retirement home in Clova, Ripon. His colorful records of the aurora polaris, and solar and terrestrial spectra all profited from his trained eye and his subtle mastery of the pen and the brush. As his paper on astronomical drawing, which we chose to reproduce in this volume, amply demonstrates, he was conversant in most of the print technology repertoire that the 19th century had to offer, and carefully selected the one most appropriate to each sujet. For instance, he chose mezzotint for the plates illustrating Maclear's observations of Halley's comet in 1835/36, so as to achieve a ``rich profundity of shadows, the deep obscurity of which is admirably adapted to reproduce those fine effects of chiaroscuro frequently found in works where the quantity of dark greatly predominates.'' The same expertise with which he tried to emulate Rembrandt's chiaroscuro effects he applied to assessing William and John Herschel's illustrations of nebulae, which appeared in print between 1811 and 1834. William Herschel's positive engraving, made partly by stippling and partly by a coarse mezzotint, receives sharp admonishment because of the visible ruled crossed lines in the background and the fact that ``the objects, which are also generally too light, [have] a much better definition than they really possess.'' On the other hand, John Herschel's illustration of nebulae and star clusters, given in negative, ``in which the lights are the darkest part of the

  20. Astronomical Instruments in India

    Science.gov (United States)

    Sarma, Sreeramula Rajeswara

    The earliest astronomical instruments used in India were the gnomon and the water clock. In the early seventh century, Brahmagupta described ten types of instruments, which were adopted by all subsequent writers with minor modifications. Contact with Islamic astronomy in the second millennium AD led to a radical change. Sanskrit texts began to lay emphasis on the importance of observational instruments. Exclusive texts on instruments were composed. Islamic instruments like the astrolabe were adopted and some new types of instruments were developed. Production and use of these traditional instruments continued, along with the cultivation of traditional astronomy, up to the end of the nineteenth century.

  1. Total hepatocellular disposition profiling of rosuvastatin and pitavastatin in sandwich-cultured human hepatocytes.

    Science.gov (United States)

    Kanda, Katsuhiro; Takahashi, Ryosuke; Yoshikado, Takashi; Sugiyama, Yuichi

    2018-04-09

    This study describes the total disposition profiling of rosuvastatin (RSV) and pitavastatin (PTV) using a single systematic procedure called D-PREX (Disposition Profile Exploration) in sandwich-cultured human hepatocytes (SCHH). The biliary excretion fractions of both statins were clearly observed, which were significantly decreased dependent on the concentration of Ko143, an inhibitor for breast cancer resistance protein (BCRP). Ko143 also decreased the basolateral efflux fraction of RSV, whereas that of PTV was not significantly affected. To understand these phenomena, effects of Ko143 on biliary excretion (BCRP and multidrug resistance-associated protein (MRP) 2) and basolateral efflux (MRP3 and MRP4) transporters were examined using transporter-expressing membrane vesicles. BCRP, MRP3 and MRP4-mediated transport of RSV was observed, and Ko143 inhibited these transporters except MRP3. BCRP and MRP4 also mediated the transport of PTV, but the Ko143-mediated inhibition was only clear for BCRP. These results might explain the Ko143-mediated complete and partial inhibition of the biliary excretion and the basolateral efflux of RSV, respectively, in SCHH. In conclusion, D-PREX with sequential sampling of supernatants prior to cell lysis enables the evaluation of total drug disposition profiles resulting from complex interplays of intracellular pathways, which would provide high-throughput evaluation of drug disposition during drug discovery. Copyright © 2018 The Japanese Society for the Study of Xenobiotics. Published by Elsevier Ltd. All rights reserved.

  2. Generation of polyclonal antibody with high avidity to rosuvastatin and its use in development of highly sensitive ELISA for determination of rosuvastatin in plasma

    Directory of Open Access Journals (Sweden)

    Al-Malaq Hamoud A

    2011-07-01

    Full Text Available Abstract In this study, a polyclonal antibody with high avidity and specificity to the potent hypocholesterolaemic agent rosuvastatin (ROS has been prepared and used in the development of highly sensitive enzyme-linked immunosorbent assay (ELISA for determination of ROS in plasma. ROS was coupled to keyhole limpt hemocyanin (KLH and bovine serum albumin (BSA using carbodiimide reagent. ROS-KLH conjugate was used for immunization of female 8-weeks old New Zealand white rabbits. The immune response of the rabbits was monitored by direct ELISA using ROS-BSA immobilized onto microwell plates as a solid phase. The rabbit that showed the highest antibody titer and avidity to ROS was scarified and its sera were collected. The IgG fraction was isolated and purified by avidity chromatography on protein A column. The purified antibody showed high avidity to ROS; IC50 = 0.4 ng/ml. The specificity of the antibody for ROS was evaluated by indirect ELISA using various competitors from the ROS-structural analogues and the therapeutic agents used with ROS in a combination therapy. The proposed ELISA involved a competitive binding reaction between ROS, in plasma sample, and the immobilized ROS-BSA for the binding sites on a limited amount of the anti-ROS antibody. The bound anti-ROS antibody was quantified with horseradish peroxidase-labeled second anti-rabbit IgG antibody (HRP-IgG and 3,3',5,5'-tetramethylbenzidine (TMB as a substrate for the peroxidase enzyme. The concentration of ROS in the sample was quantified by its ability to inhibit the binding of the anti-ROS antibody to the immobilized ROS-BSA and subsequently the color intensity in the assay wells. The assay enabled the determination of ROS in plasma at concentrations as low as 40 pg/ml.

  3. Getting Astronomers Involved in the IYA: Astronomer in the Classroom

    Science.gov (United States)

    Koenig, Kris

    2008-05-01

    The Astronomer in the Classroom program provides professional astronomers the opportunity to engage with 3rd-12th grade students across the nation in grade appropriate discussions of their recent research, and provides students with rich STEM content in a personalized forum, bringing greater access to scientific knowledge for underserved populations. 21st Century Learning and Interstellar Studios, the producer of the 400 Years of the Telescope documentary along with their educational partners, will provide the resources necessary to facilitate the Astronomer in the Classroom program, allowing students to interact with astronomers throughout the IYA2009. PROGRAM DESCRIPTION One of hundreds of astronomers will be available to interact with students via live webcast daily during Spring/Fall 2009. The astronomer for the day will conduct three 20-minute discussions (Grades 3-5 /6-8/9-12), beginning with a five-minute PowerPoint on their research or area of interest. The discussion will be followed by a question and answer period. The students will participate in real-time from their school computer(s) with the technology provided by 21st Century Learning. They will see and hear the astronomer on their screen, and pose questions from their keyboard. Teachers will choose from three daily sessions; 11:30 a.m., 12:00 p.m., 12:30 p.m. Eastern Time. This schedule overlaps all US time zones, and marginalizes bandwidth usage, preventing technological barriers to web access. The educational partners and astronomers will post materials online, providing easy access to information that will prepare teachers and students for the chosen discussion. The astronomers, invited to participate from the AAS and IAU, will receive a web cam shipment with instructions, a brief training and conductivity test, and prepaid postage for shipment of the web cam to the next astronomer on the list. The anticipated astronomer time required is 3-hours, not including the time to develop the PowerPoint.

  4. Optical studies of X-ray sources with the MASCOT - a charge-coupled device /CCD/-based astronomical instrument

    International Nuclear Information System (INIS)

    Ricker, G.R.; Bautz, M.W.; Dewey, D.; Meyer, S.S.

    1981-01-01

    The performance levels achieved by the MASCOT (MIT Astronomical Spectrometer/Camera for Optical Telescopes) on the 1.3-m telescope at the McGraw-Hill observatory in March 1981 are discussed along with preliminary data obtained in searches for optical counterparts to four 'empty-field' X-ray sources. In the W band (4000-7000 A), the MASCOT achieved a sky-limited sensitivity of +24.4 mag per sq arcsec in an 1800 s integration. The ability to flatten pictures to a level consistent with (sky + source) photon statistics and readout noise was demonstrated. For the four sources observed, an optical counterpart was established for one source (1413+13) based on positional coincidence (better than 1.8 arcsec), four possible candidates were detected in the error box of another source (1009 35) and upper sensitivity limits were established for optical counterparts in the error boxes for the other two sources (0920+39 and 0931-11)

  5. Extracting meaning from astronomical telegrams

    Science.gov (United States)

    Graham, Matthew; Conwill, L.; Djorgovski, S. G.; Mahabal, A.; Donalek, C.; Drake, A.

    2011-01-01

    The rapidly emerging field of time domain astronomy is one of the most exciting and vibrant new research frontiers, ranging in scientific scope from studies of the Solar System to extreme relativistic astrophysics and cosmology. It is being enabled by a new generation of large synoptic digital sky surveys - LSST, PanStarrs, CRTS - that cover large areas of sky repeatedly, looking for transient objects and phenomena. One of the biggest challenges facing these is the automated classification of transient events, a process that needs machine-processible astronomical knowledge. Semantic technologies enable the formal representation of concepts and relations within a particular domain. ATELs (http://www.astronomerstelegram.org) are a commonly-used means for reporting and commenting upon new astronomical observations of transient sources (supernovae, stellar outbursts, blazar flares, etc). However, they are loose and unstructured and employ scientific natural language for description: this makes automated processing of them - a necessity within the next decade with petascale data rates - a challenge. Nevertheless they represent a potentially rich corpus of information that could lead to new and valuable insights into transient phenomena. This project lies in the cutting-edge field of astrosemantics, a branch of astroinformatics, which applies semantic technologies to astronomy. The ATELs have been used to develop an appropriate concept scheme - a representation of the information they contain - for transient astronomy using aspects of natural language processing. We demonstrate that it is possible to infer the subject of an ATEL from the vocabulary used and to identify previously unassociated reports.

  6. Astronomical Signatures of Dark Matter

    Directory of Open Access Journals (Sweden)

    Paul Gorenstein

    2014-01-01

    Full Text Available Several independent astronomical observations in different wavelength bands reveal the existence of much larger quantities of matter than what we would deduce from assuming a solar mass to light ratio. They are very high velocities of individual galaxies within clusters of galaxies, higher than expected rotation rates of stars in the outer regions of galaxies, 21 cm line studies indicative of increasing mass to light ratios with radius in the halos of spiral galaxies, hot gaseous X-ray emitting halos around many elliptical galaxies, and clusters of galaxies requiring a much larger component of unseen mass for the hot gas to be bound. The level of gravitational attraction needed for the spatial distribution of galaxies to evolve from the small perturbations implied by the very slightly anisotropic cosmic microwave background radiation to its current web-like configuration requires much more mass than is observed across the entire electromagnetic spectrum. Distorted shapes of galaxies and other features created by gravitational lensing in the images of many astronomical objects require an amount of dark matter consistent with other estimates. The unambiguous detection of dark matter and more recently evidence for dark energy has positioned astronomy at the frontier of fundamental physics as it was in the 17th century.

  7. LGBT Workplace Issues for Astronomers

    Science.gov (United States)

    Kay, Laura E.; Danner, R.; Sellgren, K.; Dixon, V.; GLBTQastro

    2011-01-01

    Federal Equal Employment Opportunity laws and regulations do not provide protection from discrimination on the basis of sexual orientation or gender identity or gender expression. Sexual minority astronomers (including lesbian, gay, bisexual and transgender people; LGBT) can face additional challenges at school and work. Studies show that LGBT students on many campuses report experiences of harassment. Cities, counties, and states may or may not have statutes to protect against such discrimination. There is wide variation in how states and insurance plans handle legal and medical issues for transgender people. Federal law does not acknowledge same-sex partners, including those legally married in the U.S. or in other countries. Immigration rules in the U.S. (and many other, but not all) countries do not recognize same-sex partners for visas, employment, etc. State `defense of marriage act' laws have been used to remove existing domestic partner benefits at some institutions, or benefits can disappear with a change in governor. LGBT astronomers who change schools, institutions, or countries during their career may experience significant differences in their legal, medical, and marital status.

  8. New Life for Astronomical Instruments of the Past at the Astronomical Observatory of Taras Shevchenko

    Science.gov (United States)

    Kazantseva, Liliya

    2012-09-01

    Astronomical instruments of the past are certainly valuable artifacts of the history of science and education. Like other collections of scientific equipment, they also demonstrate i) development of scientific and technical ideas, ii) technological features of the historical period, iii) professional features of artists or companies -- manufacturers, and iv) national and local specificity of production. However, astronomical instruments are also devices made for observations of rare phenomena -- solar eclipses, transits of planets of the solar disk, etc. Instruments used to study these rare events were very different for each event, since the science changed quickly between events. The Astronomical Observatory of Kyiv National Taras Shevchenko University has a collection of tools made by leading European and local shops from the early nineteenth century. These include tools for optically observing the first artificial Earth satellites, photography, chronometry, and meteorology. In addition, it has assembled a library of descriptions of astronomical instruments and makers'price-lists. Of particular interest are the large stationary tools that are still active in their pavilions. Almost every instrument has a long interesting history. Museification of astronomical instruments gives them a second life, expanding educational programs and tracing the development of astronomy in general and scientific institution and region in particular. It would be advisable to first create a regional database of these rare astronomical instruments (which is already being done in Ukraine), then a common global database. By combining all the historical information about astronomical instruments with the advantages of the Internet, you can show the full evolution of an astronomical instrument with all its features. Time is relentless, and much is destroyed, badly kept and thrown in the garbage. We need time to protect, capture, and tell about it.

  9. Rosuvastatin reduces neointima formation in a rat model of balloon injury

    Directory of Open Access Journals (Sweden)

    Preusch MR

    2010-11-01

    Full Text Available Abstract Background Processes of restenosis, following arterial injury, are complex involving different cell types producing various cytokines and enzymes. Among those enzymes, smooth muscle cell-derived matrix metalloproteinases (MMPs are thought to take part in cell migration, degrading of extracellular matrix, and neointima formation. MMP-9, also known as gelatinase B, is expressed immediately after vascular injury and its expression and activity can be inhibited by statins. Using an established in vivo model of vascular injury, we investigated the effect of the HMG-CoA reductase inhibitor rosuvastatin on MMP-9 expression and neointima formation. Materials and methods 14-week old male Sprague Dawley rats underwent balloon injury of the common carotid artery. Half of the animals received rosuvastatin (20 mg/kg body weight/day via oral gavage, beginning 3 days prior to injury. Gelatinase activity and neointima formation were analyzed 3 days and 14 days after balloon injury, respectively. 14 days after vascular injury, proliferative activity was assessed by staining for Ki67. Results After 14 days, animals in the rosuvastatin group showed a decrease in total neointima formation (0.194 ± 0.01 mm2 versus 0.124 ± 0.02 mm2, p Conclusions Rosuvastatin attenuates neointima formation without affecting early MMP-9 activity in a rat model of vascular injury.

  10. Early results from the Infrared Astronomical Satellite

    International Nuclear Information System (INIS)

    Neugebauer, G.; Beichman, C.A.; Soifer, B.T.

    1984-01-01

    For 10 months the Infrared Astronomical Satellite (IRAS) provided astronomers with what might be termed their first view of the infrared sky on a clear, dark night. Without IRAS, atmospheric absorption and the thermal emission from both the atmosphere and Earthbound telescopes make the task of the infrared astronomer comparable to what an optical astronomer would face if required to work only on cloudy afternoons. IRAS observations are serving astronomers in the same manner as the photographic plates of the Palomar Observatory Sky Survey; just as the optical survey has been used by all astronomers for over three decades, as a source of quantitative information about the sky and as a roadmap for future observations, the results of IRAS will be studied for years to come. IRAS has demonstrated the power of infrared astronomy from space. Already, from a brief look at a miniscule fraction of the data available, we have learned much about the solar system, about nearby stars, about the Galaxy as a whole and about distant extragalactic systems. Comets are much dustier than previously thought. Solid particles, presumably the remnants of the star-formation process, orbit around Vega and other stars and may provide the raw material for planetary systems. Emission from cool interstellar material has been traced throughout the Galaxy all the way to the galactic poles. Both the clumpiness and breadth of the distribution of this material were previously unsuspected. The far-infrared sky away from the galactic plane has been found to be dominate by spiral galaxies, some of which emit more than 50% and as much as 98% of their energy in the infrared - an exciting and surprising revelation. The IRAS mission is clearly the pathfinder for future mission that, to a large extent, will be devoted to the discoveries revealed by IRAS. 8 figures

  11. BOOK REVIEW: The Wandering Astronomer

    Science.gov (United States)

    Swinbank, Elizabeth

    2000-09-01

    Fans of Patrick Moore will like this book. I enjoyed it more than I expected, having anticipated a collection of personal anecdotes of the type favoured by certain tedious after-dinner speakers. Some of the 41 short items it contains do tend towards that category, but there are also some nuggets which might enliven your physics teaching. For example, did you know that, in a murder trial in 1787, the defendant's belief that the Sun was inhabited was cited as evidence of his insanity? This was despite his views being shared by many astronomers of the day including William Herschel. Or that Clyde Tombaugh had a cat called Pluto after the planet he discovered, which was itself named by an eleven-year-old girl? Another gem concerns a brief flurry, in the early 1990s, over a suspected planet orbiting a pulsar; variations in the arrival time of its radio pulses indicated the presence of an orbiting body. These shifts were later found to arise from an error in a computer program that corrected for the Earth's motion. The programmer had assumed a circular orbit for the Earth whereas it is actually elliptical. The book is clearly intended for amateur astronomers and followers of Patrick Moore's TV programmes. There is plenty of astronomy, with an emphasis on the solar system, but very little astrophysics. The author's metricophobia means that quantities are given in imperial units throughout, with metric equivalents added in brackets (by an editor, I suspect) which can get irritating, particularly as powers-of-ten notation is avoided. It is quite a novelty to see the temperature for hydrogen fusion quoted as 18 000 000 °F (10 000 000 °C). By way of contrast, astronomical terms are used freely - ecliptic, first-magnitude star, and so on. Such terms are defined in a glossary at the end, but attention is not drawn to this and I only stumbled across it by chance. Patrick Moore obviously knows his public, and this book will serve them well. For physics teachers and students

  12. An astronomical observatory for Peru

    Science.gov (United States)

    del Mar, Juan Quintanilla; Sicardy, Bruno; Giraldo, Víctor Ayma; Callo, Víctor Raúl Aguilar

    2011-06-01

    Peru and France are to conclude an agreement to provide Peru with an astronomical observatory equipped with a 60-cm diameter telescope. The principal aims of this project are to establish and develop research and teaching in astronomy. Since 2004, a team of researchers from Paris Observatory has been working with the University of Cusco (UNSAAC) on the educational, technical and financial aspects of implementing this venture. During an international astronomy conference in Cusco in July 2009, the foundation stone of the future Peruvian Observatory was laid at the top of Pachatusan Mountain. UNSAAC, represented by its Rector, together with the town of Oropesa and the Cusco regional authority, undertook to make the sum of 300,000€ available to the project. An agreement between Paris Observatory and UNSAAC now enables Peruvian students to study astronomy through online teaching.

  13. Closing remarks: astronomical

    International Nuclear Information System (INIS)

    Pecker, J.-C.

    1990-01-01

    During the discussions we have covered many facets of the basic interactions between solar activity and the Earth's climate. Solar activity is not the only astronomical or astrophysical phenomenon to influence physical conditions in the biosphere. Over timescales an order of magnitude less, the location of the Solar System in the Galaxy may have influenced life on Earth. The Sun is a complex generator of radiation, particles and magnetic fields sent far into space. Even if the total radiation emitted is constant, the amount of radiation received by the Earth changes with time: this change is complex and involved with a redistribution of energy emitted at different solar latitudes than to a real change in solar luminosity. These changes in the Earth's illumination may be a function of the wavelength, and have various effects in different layers of the Earth's atmosphere. The Sun also emits particles of all energies. Some of them find their way through the magnetopause, giving rise to auroras, to magnetic storms, to ionospheric disturbances and the like. The possible climatological effects are yet obscure. To understand the solar terrestrial relations better, regular, routine observations from ground-based stations and from space of solar phenomena must be continued. The sensitivity of human life to small changes in climatic conditions is very large. A good knowledge of solar-physics is therefore important and relevant. (author)

  14. Astronomical Books and Charts in the Book of Bibliographie Coreenne

    Directory of Open Access Journals (Sweden)

    Ki-Won Lee

    2008-06-01

    Full Text Available We investigate astronomical materials listed in the book of Bibliographie Coreenne written by Maurice Courant. He classified ancient Korean books into nine Divisions (部 and thirty six Classes (類, and published them as three volumes (ranging from 1894 to 1896 and one supplement (in 1901. In total, 3,821 books including astronomical ones are listed together with information on physical size, possessional place, bibliographical note, and so forth. Although this book is an essential one in the field of Korea bibliography and contains many astronomical materials such as Cheon-Mun-Ryu-Cho 天文類抄, Si-Heon-Seo 時憲書, and Cheon-Sang-Yeol-Cha-Bun-Ya-Ji-Do 天象列次分野之圖, it has not been well known to the public nor to astronomical society. Of 3,821 catalogues, we found that about 50 Items (種 are related to astronomy or astrology, and verified that most of them are located in the Kyujanggak Royal Library 奎章閣. We also found an unknown astronomical chart, Hon-Cheon-Chong-Seong-Yeol-Cha-Bun-Ya-Ji-Do 渾天總星列次分野之圖. Because those astronomical materials are not well known to international astronomical community and there have been few studies on the materials in Korea, we here introduce and review them, particularly with the astronomical viewpoint.

  15. Astronomical Books and Charts in the Book of Bibliographie Coreenne

    Science.gov (United States)

    Lee, Ki-Won; Yang, Hong-Jin; Park, Myeong-Gu

    2008-06-01

    We investigate astronomical materials listed in the book of Bibliographie Coréenne written by Maurice Courant. He classified ancient Korean books into nine Divisions (?) and thirty six Classes (?), and published them as three volumes (ranging from 1894 to 1896) and one supplement (in 1901). In total, 3,821 books including astronomical ones are listed together with information on physical size, possessional place, bibliographical note, and so forth. Although this book is an essential one in the field of Korea bibliography and contains many astronomical materials such as Cheon-Mun-Ryu-Cho ????, Si-Heon-Seo ??????, and Cheon-Sang-Yeol-Cha-Bun-Ya-Ji-Do ????????, it has not been well known to the public nor to astronomical society. Of 3,821 catalogues, we found that about 50 Items (?) are related to astronomy or astrology, and verified that most ! of them are located in the Kyujanggak Royal Library ???. We also found an unknown astronomical chart, Hon-Cheon-Chong-Seong-Yeol-Cha-Bun-Ya-Ji-Do ??????????. Because those astronomical materials are not well known to international astronomical community and there have been few studies on the materials in Korea, we here introduce and review them, particularly with the astronomical viewpoint.

  16. Using commercial amateur astronomical spectrographs

    CERN Document Server

    Hopkins, Jeffrey L

    2014-01-01

    Amateur astronomers interested in learning more about astronomical spectroscopy now have the guide they need. It provides detailed information about how to get started inexpensively with low-resolution spectroscopy, and then how to move on to more advanced  high-resolution spectroscopy. Uniquely, the instructions concentrate very much on the practical aspects of using commercially-available spectroscopes, rather than simply explaining how spectroscopes work. The book includes a clear explanation of the laboratory theory behind astronomical spectrographs, and goes on to extensively cover the practical application of astronomical spectroscopy in detail. Four popular and reasonably-priced commercially available diffraction grating spectrographs are used as examples. The first is a low-resolution transmission diffraction grating, the Star Analyser spectrograph. The second is an inexpensive fiber optic coupled bench spectrograph that can be used to learn more about spectroscopy. The third is a newcomer, the ALPY ...

  17. Astronomical databases of Nikolaev Observatory

    Science.gov (United States)

    Protsyuk, Y.; Mazhaev, A.

    2008-07-01

    Several astronomical databases were created at Nikolaev Observatory during the last years. The databases are built by using MySQL search engine and PHP scripts. They are available on NAO web-site http://www.mao.nikolaev.ua.

  18. Astronomical Instrumentation System Markup Language

    Science.gov (United States)

    Goldbaum, Jesse M.

    2016-05-01

    The Astronomical Instrumentation System Markup Language (AISML) is an Extensible Markup Language (XML) based file format for maintaining and exchanging information about astronomical instrumentation. The factors behind the need for an AISML are first discussed followed by the reasons why XML was chosen as the format. Next it's shown how XML also provides the framework for a more precise definition of an astronomical instrument and how these instruments can be combined to form an Astronomical Instrumentation System (AIS). AISML files for several instruments as well as one for a sample AIS are provided. The files demonstrate how AISML can be utilized for various tasks from web page generation and programming interface to instrument maintenance and quality management. The advantages of widespread adoption of AISML are discussed.

  19. Sixteenth Century Astronomical Telescopy

    Science.gov (United States)

    Usher, P. D.

    2001-12-01

    Ophelia in Shakespeare's Hamlet is named for the ``moist star" which in mythology is the partner of Hamlet's royal Sun. Together the couple seem destined to rule on earth just as their celestial counterparts rule the heavens, but the tragedy is that they are afflicted, just as the Sun and Moon are blemished. In 1.3 Laertes lectures Ophelia on love and chastity, describing first Cytherean phases (crescent to gibbous) and then Lunar craters. Spots mar the Sun (1.1, 3.1). Also reported are Jupiter's Red Spot (3.4) and the resolution of the Milky Way into stars (2.2). These interpretations are well-founded and support the cosmic allegory. Observations must have been made with optical aid, probably the perspective glass of Leonard Digges, father of Thomas Digges. Notably absent from Hamlet is mention of the Galilean moons, owing perhaps to the narrow field-of-view of the telescope. That discovery is later celebrated in Cymbeline, published soon after Galileo's Siderius Nuncius in 1610. In 5.4 of Cymbeline the four ghosts dance ``in imitation of planetary motions" and at Jupiter's behest place a book on the chest of Posthumus Leonatus. His name identifies the Digges father and son as the source of data in Hamlet since Jupiter's moons were discovered after the deaths of Leonard (``leon+hart") and Thomas (the ``lion's whelp"). Lines in 5.4 urge us not to read more into the book than is contained between its covers; this is understandable because Hamlet had already reported the other data in support of heliocentricism and the cosmic model discussed and depicted by Thomas Digges in 1576. I conclude therefore that astronomical telescopy began in England before the last quarter of the sixteenth century.

  20. Enthusiastic Little Astronomers

    Science.gov (United States)

    Novak, Ines

    2016-04-01

    Younger primary school students often show great interest in the vast Universe hiding behind the starry night's sky, but don't have a way of learning about it and exploring it in regular classes. Some of them would search children's books, Internet or encyclopedias for information or facts they are interested in, but there are those whose hunger for knowledge would go unfulfilled. Such students were the real initiators of our extracurricular activity called Little Astronomers. With great enthusiasm they would name everything that interests them about the Universe that we live in and I would provide the information in a fun and interactive yet acceptable way for their level of understanding. In our class we learn about Earth and its place in the Solar System, we learn about the planets and other objects of our Solar System and about the Sun itself. We also explore the night sky using programs such as Stellarium, learning to recognize constellations and name them. Most of our activities are done using a PowerPoint presentation, YouTube videos, and Internet simulations followed by some practical work the students do themselves. Because of the lack of available materials and funds, most of materials are hand made by the teacher leading the class. We also use the school's galileoscope as often as possible. Every year the students are given the opportunity to go to an observatory in a town 90 km away so that they could gaze at the sky through the real telescope for the first time. Our goal is to start stepping into the world of astronomy by exploring the secrets of the Universe and understanding the process of rotation and revolution of our planet and its effects on our everyday lives and also to become more aware of our own role in our part of the Universe. The hunger for knowledge and enthusiasm these students have is contagious. They are becoming more aware of their surroundings and also understanding their place in the Universe that helps them remain humble and helps

  1. MECHANISTIC STUDIES ON THE PHOTOTOXICITY OF ROSUVASTATIN, ITRACONAZOLE AND IMATINIB

    OpenAIRE

    Nardi, Giacomo

    2016-01-01

    Photosensitizing effects of xenobiotics are of increasing concern in public health since modern lifestyle often associates sunlight exposure with the presence of chemical substances in the skin. An important number of chemicals like perfumes, sunscreen components, or therapeutic agents have been reported as photosensitizers. In this context, a considerable effort has been made to design a model system for photosafety assessment. Indeed, screening for phototoxicity is necessary ...

  2. A SURVEY OF ASTRONOMICAL RESEARCH: A BASELINE FOR ASTRONOMICAL DEVELOPMENT

    International Nuclear Information System (INIS)

    Ribeiro, V. A. R. M.; Russo, P.; Cárdenas-Avendaño, A.

    2013-01-01

    Measuring scientific development is a difficult task. Different metrics have been put forward to evaluate scientific development; in this paper we explore a metric that uses the number of peer-reviewed, and when available non-peer-reviewed, research articles as an indicator of development in the field of astronomy. We analyzed the available publication record, using the Smithsonian Astrophysical Observatory/NASA Astrophysics Database System, by country affiliation in the time span between 1950 and 2011 for countries with a gross national income of less than 14,365 USD in 2010. This represents 149 countries. We propose that this metric identifies countries in ''astronomical development'' with a culture of research publishing. We also propose that for a country to develop in astronomy, it should invest in outside expert visits, send its staff abroad to study, and establish a culture of scientific publishing. Furthermore, we propose that this paper may be used as a baseline to measure the success of major international projects, such as the International Year of Astronomy 2009

  3. Nikolay N. Donitch - the astronomer

    Science.gov (United States)

    Gaina, Alex B.; Volyanskaya, M. Yu.

    1999-08-01

    The article is devoted to milestones of life and scientific activity of the eminent astronomer Nikolay Nikolaevich Donitch (Nicolae N. Donici) (1874-1956), a graduate from the Odessa (Novorossiski) university. He was a wellknown expert in the field of reseacrh of objects of Solar system. A person highly cultured, which built the first in Bessarabia (actually a part of the Republic of Moldova) observatory. He was borne in Kishinev (Chisinau) in a nobles family of notable Moldavian landersmen. N.D. graduated from the Richelieu lyceym in Odessa and afterwards, in 1897, graduated from the Odessa (Novorossiysky) University. A.K. Kononovich (1850-1910)headed the chair of astronomy and the Observatory at that time - a foremost authority in the field of astrophysics and stellar astronomy. Many of his disciples became eminent scientists of their time. N. Donitch was among them. N.D. worked till 1918 at Pulkovo Observatory and became a master in the field of studying of such phenomena as solar and lunar eclipses. To observe the Sun N.D., could afford to design and manufacture a spectroheliograph, the first in Russia, with the assistance of a famous Odessa mechanic J.A. Timchenko. This instrument enabled him to obtain topquality photos of the Sun's surface and prominences. It was mounted together with coelostat in the private observatory of N.D. , built in the village Staryie Doubossary in 1908. Besides the heliograoph, the observatory was equiped with a five inch refractor-equatorial with numerous instruments for various observations. Of the other instruments should be mentioned : "a comet triplet" - an instrument consisting of guiding refractor, a photographic camera and a spectrograph with an objective prism. N.D. was lucky enough to observe rare astronomical phenomena. He observed the transit of Mercury through the disk of the Sun on November 14, 1907 and showed the athmosphere absence around this planet, observed the Halley's comet in 1910, the bright Pons-Winneke comet

  4. Choosing and using astronomical eyepieces

    CERN Document Server

    Paolini, William

    2013-01-01

    This valuable reference fills a number of needs in the field of astronomical eyepieces, including that of a buyer's guide, observer's field guide and technical desk reference. It documents the past market for eyepieces and its evolution right up to the present day. In addition to appealing to practical astronomers - and potentially saving them money - it is useful both as a historical reference and as a detailed review of the current market place for this bustling astronomical consumer product. What distinguishes this book from other publications on astronomy is the involvement of observers from all aspects of the astronomical community, and also the major manufacturers of equipment. It not only catalogs the technical aspects of the many modern eyepieces but also documents amateur observer reactions and impressions of their utility over the years, using many different eyepieces. Eyepieces are the most talked-about accessories and collectible items available to the amateur astronomer. No other item of equi...

  5. Astronomical Knowledge in Holy Books

    Science.gov (United States)

    Farmanyan, Sona V.; Mickaelian, Areg M.

    2015-08-01

    We investigate religious myths related to astronomy from different cultures in an attempt to identify common subjects and characteristics. The paper focuses on astronomy in religion. The initial review covers records from Holy books about sky related superstitious beliefs and cosmological understanding. The purpose of this study is to introduce sky related religious and national traditions (particularly based on different calendars; Solar or Lunar). We carried out a comparative study of astronomical issues contained in a number of Holy books: Ancient Egyptian Religion (Pyramid Texts), Zoroastrianism (Avesta), Hinduism (Vedas), Buddhism (Tipitaka), Confucianism (Five Classics), Sikhism (Guru Granth Sahib), Christianity (Bible), Islam (Quran), Druidism (Mabinogion) and Maya Religion (Popol Vuh). These books include various information on the creation of the Universe, Sun and Moon, the age of the Universe, Cosmic sizes, understanding about the planets, stars, Milky Way and description of the Heavens in different religions. We come to the conclusion that the perception of celestial objects varies from culture to culture, and from religion to religion and preastronomical views had a significant impact on humankind, particularly on religious diversities. We prove that Astronomy is the basis of cultures, and that national identity and mythology and religion were formed due to the special understanding of celestial objects.

  6. Astronomical Image and Data Analysis

    CERN Document Server

    Starck, J.-L

    2006-01-01

    With information and scale as central themes, this comprehensive survey explains how to handle real problems in astronomical data analysis using a modern arsenal of powerful techniques. It treats those innovative methods of image, signal, and data processing that are proving to be both effective and widely relevant. The authors are leaders in this rapidly developing field and draw upon decades of experience. They have been playing leading roles in international projects such as the Virtual Observatory and the Grid. The book addresses not only students and professional astronomers and astrophysicists, but also serious amateur astronomers and specialists in earth observation, medical imaging, and data mining. The coverage includes chapters or appendices on: detection and filtering; image compression; multichannel, multiscale, and catalog data analytical methods; wavelets transforms, Picard iteration, and software tools. This second edition of Starck and Murtagh's highly appreciated reference again deals with to...

  7. Choosing and using astronomical filters

    CERN Document Server

    Griffiths, Martin

    2014-01-01

    As a casual read through any of the major amateur astronomical magazines will demonstrate, there are filters available for all aspects of optical astronomy. This book provides a ready resource on the use of the following filters, among others, for observational astronomy or for imaging: Light pollution filters Planetary filters Solar filters Neutral density filters for Moon observation Deep-sky filters, for such objects as galaxies, nebulae and more Deep-sky objects can be imaged in much greater detail than was possible many years ago. Amateur astronomers can take

  8. EDUCATIONAL ASTRONOMICAL OBSERVATIONS ON REMOTE ACCESS TELESCOPES

    Directory of Open Access Journals (Sweden)

    Ivan P. Kriachko

    2016-01-01

    Full Text Available The purpose of this article is to show the way of overcoming one of the major problems of astronomy teaching methods in upper secondary school – organization of educational astronomical observations. Nowadays it became possible to perform such observations on remote access telescopes. By using up-to-date informational and communicational technologies, having an opportunity to work with robotic telescopes allows us to organize a unique cognitive and research oriented activities for students while conducting their specialized astronomical studies. Below here is given a brief description of the most significant robotic telescopes and the way of the usage of open remote access telescopic network which was created by professors and scientists of Harvard-Smithsonian Center for Astrophysics, USA.

  9. Astronomical dating in the 19th century

    Science.gov (United States)

    Hilgen, Frederik J.

    2010-01-01

    layering in Holocene peat bogs. He specifically linked the exceptionally wet Atlantic period to the prolonged precession minimum at 33,300 yr ago and further related basic stratigraphic alternations to precession induced climate change in general. Such a linkage was also proposed by Grove Karl Gilbert for cyclic alternations in the marine Cretaceous of North America. Extrapolating sedimentation rates, he arrived at an astronomical duration for part of the Cretaceous that was roughly as long as the final estimate of William Thomson for the age of the Earth. Assuming that orbital parameters directly affect sea level, Karl Mayer-Eymar and Blytt correlated the well known succession of Tertiary stages to precession and eccentricity, respectively. Remarkably, Blytt, like Croll before him, used very long-period cycles in eccentricity to establish and validate his tuning. Understandably these studies in the second half of the 19th century were largely deductive in nature and proved partly incorrect later. Nevertheless, this fascinating period marks a crucial phase in the development of the astronomical theory of the ice ages and climate, and in astronomical dating. It preceded the final inductive phase, which started with the recovery of deep-sea cores in 1947 and led to a spectacular revival of the astronomical theory, by a century. The first half of the 20th century can best be regarded as an intermediate phase, despite the significant progress made in both theoretical aspects and tuning.

  10. Astronomical Spectroscopy A Short History

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 3; Issue 5. Astronomical Spectroscopy A Short History. J C Bhattacharyya. General Article Volume 3 Issue 5 May 1998 pp 24-29. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/003/05/0024-0029 ...

  11. Applying artificial intelligence to astronomical databases - a surveyof applicable technology.

    Science.gov (United States)

    Rosenthal, D. A.

    This paper surveys several emerging technologies which are relevant to astronomical database issues such as interface technology, internal database representation, and intelligent data reduction aids. Among the technologies discussed are natural language understanding, frame and object representations, planning, pattern analysis, machine learning and the nascent study of simulated neural nets. These techniques will become increasingly important for astronomical research, and in particular, for applications with large databases.

  12. Latin American astronomers and the International Astronomical Union

    Science.gov (United States)

    Torres-Peimbert, S.

    2017-07-01

    Selected aspects of the participation of the Latin American astronomers in the International Astronomical Union are presented: Membership, Governing bodies, IAU meetings, and other activities. The Union was founded in 1919 with 7 initial member states, soon to be followed by Brazil. In 1921 Mexico joined, and in 1928 Argentina also formed part of the Union, while Chile joined in 1947. In 1961 Argentina, Brazil, Chile, Mexico and Venezuela were already member countries. At present (October 2016) 72 countries contribute financially to the Union. The Union lists 12,391 professional astronomers as individual members; of those, 692 astronomers work in Latin America and the Caribbean, from 13 member states (Argentina, Bolivia , Brazil, Chile, Colombia, Costa Rica, Cuba, Honduras, Mexico, Panamá, Perú, Uruguay and Venezuela) as well as from Ecuador and Puerto Rico. This group comprises 5.58% of the total membership, a figure somewhat lower than the fraction of the population in the region, which is 8.6% of the world population. Of the Latin American members, 23.4% are women and 76.6% are men; slightly higher than the whole membership of Union, which is of 16.9%. In the governing bodies it can be mentioned that there have been 2 Presidents of the Union (Jorge Sahade and Silvia Torres-Peimbert), 7 VicePresidents (Guillermo Haro, Jorge Sahade, Manuel Peimbert Claudio Anguita, Silvia Torres-Peimbert, Beatriz Barbuy, and Marta G. Rovira). The IAU meetings held in the region, include 2 General Assemblies (the 1991 XXI GA took place in Buenos Aires, Argentina and the 2009 XXVIII GA, in Rio de Janeiro, Brazil), 15 Regional Meetings (in Argentina, Brazil, Chile, Colombia, Mexico, Venezuela and Uruguay), 29 Symposia (in Argentina, Brazil, Chile, Colombia, Costa Rica, Ecuador, Peru and Mexico), 5 Colloquia (in Argentina and Mexico), 8 International Schools for Young Astronomers (in Argentina, Brazil, Cuba, Honduras and Mexico), and 11 projects sponsored by the Office of Astronomy

  13. Astronomers Unveiling Life's Cosmic Origins

    Science.gov (United States)

    2009-02-01

    Processes that laid the foundation for life on Earth -- star and planet formation and the production of complex organic molecules in interstellar space -- are yielding their secrets to astronomers armed with powerful new research tools, and even better tools soon will be available. Astronomers described three important developments at a symposium on the "Cosmic Cradle of Life" at the annual meeting of the American Association for the Advancement of Science in Chicago, IL. Chemistry Cycle The Cosmic Chemistry Cycle CREDIT: Bill Saxton, NRAO/AUI/NSF Full Size Image Files Chemical Cycle Graphic (above image, JPEG, 129K) Graphic With Text Blocks (JPEG, 165K) High-Res TIFF (44.2M) High-Res TIFF With Text Blocks (44.2M) In one development, a team of astrochemists released a major new resource for seeking complex interstellar molecules that are the precursors to life. The chemical data released by Anthony Remijan of the National Radio Astronomy Observatory (NRAO) and his university colleagues is part of the Prebiotic Interstellar Molecule Survey, or PRIMOS, a project studying a star-forming region near the center of our Milky Way Galaxy. PRIMOS is an effort of the National Science Foundation's Center for Chemistry of the Universe, started at the University of Virginia (UVa) in October 2008, and led by UVa Professor Brooks H. Pate. The data, produced by the NSF's Robert C. Byrd Green Bank Telescope (GBT) in West Virginia, came from more than 45 individual observations totalling more than nine GigaBytes of data and over 1.4 million individual frequency channels. Scientists can search the GBT data for specific radio frequencies, called spectral lines -- telltale "fingerprints" -- naturally emitted by molecules in interstellar space. "We've identified more than 720 spectral lines in this collection, and about 240 of those are from unknown molecules," Remijan said. He added, "We're making available to all scientists the best collection of data below 50 GHz ever produced for

  14. Cost-Effectiveness Analysis of Atorvastatin versus Rosuvastatin in Primary and Secondary Cardiovascular Prevention Populations in Brazil and Columbia.

    Science.gov (United States)

    Mould-Quevedo, Joaquín F; Gutiérrez-Ardila, Magda Vianey; Ordóñez Molina, Jaime Eduardo; Pinsky, Brett; Vargas Zea, Nicolás

    2014-12-01

    Latin America has witnessed a marked increase in cardiovascular (CV) disease, the leading cause of death in many countries. The benefits of lipid-lowering therapy to reduce CV-related events are widely accepted. Clinical evidence suggests that rosuvastatin is associated with slightly greater reductions in low-density lipoprotein cholesterol levels than is atorvastatin at comparable doses. Rosuvastatin, however, is often priced at a premium. Our objective was to examine the cost-effectiveness of using atorvastatin versus rosuvastatin in reducing CV events in Brazil and Colombia using real-world prices. A global Markov cohort model of primary and secondary CV prevention was developed and adapted to Brazilian and Colombian settings. The risks and costs of major CV events and efficacy, adherence, and costs of statins were considered. Total gains in life-years, quality-adjusted life-years, major CV events avoided, and costs over the lifetime horizon were estimated. Several dose comparisons were considered. In the Colombian analyses, differences in drug costs between therapies were considerable while outcomes were similar. The incremental cost per quality-adjusted life-year gained for rosuvastatin versus atorvastatin was more than $700,000 and $200,000 in primary and secondary prevention, respectively. Brazilian analyses found lower incremental cost-effectiveness ratios for rosuvastatin at some dose comparisons due to similar pricing between statins. Sensitivity analyses revealed that changes in treatment efficacy and adherence had the largest impact on results. In primary and secondary CV prevention, the efficacy advantage of rosuvastatin was minimal, while its acquisition cost was higher, particularly in Colombia. The incremental cost-effectiveness ratios were, therefore, generally in favor of atorvastatin being the cost-effective option. Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights

  15. The astronomical tables of Giovanni Bianchini

    CERN Document Server

    Chabas, Jose

    2009-01-01

    This book describes and analyses, for the first time, the astronomical tables of Giovanni Bianchini of Ferrara (d. after 1469), explains their context, inserts them into an astronomical tradition that began in Toledo, and addresses their diffusion.

  16. Astronomical Heritage in the National Culture

    Science.gov (United States)

    Harutyunian, H. A.; Mickaelian, A. M.; Parsamian, E. S.

    2014-10-01

    The book contains Proceedings of the Archaeoastronomical Meeting "Astronomical Heritage in the National Culture" Dedicated to Anania Shirakatsi's 1400th Anniversary and XI Annual Meeting of the Armenian Astronomical Society. It consists of 3 main sections: "Astronomical Heritage", "Anania Shirakatsi" and "Modern Astronomy", as well as Literature about Anania Shirakatsi is included. The book may be interesting for astronomers, historians, archaeologists, linguists, students and other readers.

  17. Use of a combination of prednisolone and rosuvastatin for treatment of a pyogranuloma in a dog.

    Science.gov (United States)

    Yuki, Masashi; Hirano, Takashi

    2010-04-01

    A 6-year-old spayed female Miniature Dachshund was examined because of a 3-day history of anorexia and diarrhea. A lump was detected during abdominal palpation. Biochemical abnormalities included increases in serum concentrations of total protein, globulin, and C-reactive protein (CRP). Abdominal radiography and abdominal ultrasonography revealed a mass on the caudal aspect of the right kidney. Exploratory laparotomy confimed the mass; however, it could not be excised because it was strongly adhered to surrounding tissues. Histologic examination of a tissue sample from the mass led to a diagnosis of pyogranuloma. The dog was treated with rosuvastatin, but no improvement was evident. Administration of a high dose of prednisolone (1 mg/kg [0.45 mg/lb], PO, q 12 h) was initiated. The CRP concentration returned to within reference limits, and the mass gradually decreased in size. The prednisolone dosage was tapered to 0.14 mg/kg (0.064 mg/lb), PO, every 12 hours. However, once the low dosage of prednisolone was reached, CRP concentration and size of the mass increased. Rosuvastatin was subsequently combined with the low dosage of prednisolone. After 1 week of the combination treatment, the CRP concentration returned to within reference limits, and the mass was reduced in size. The mass eventually could not be detected ultrasonographically. A low dose of prednisolone was not effective against the pyogranuloma. However, administration of a low dose of prednisolone in combination with rosuvastatin caused decreases in CRP concentration and size of the pyogranuloma. Thus, statins may act as immunosuppressants.

  18. Astronomical Spectroscopy -24 ...

    Indian Academy of Sciences (India)

    growth of spectroscopy and its application to the study of .... Cesium was discovered ten years earlier, in 1859; it is the ... Kirchhoff and Bunsen's discovery; he was spared the pain of seeing ... We will have to go back about twenty years.

  19. Super resolution for astronomical observations

    Science.gov (United States)

    Li, Zhan; Peng, Qingyu; Bhanu, Bir; Zhang, Qingfeng; He, Haifeng

    2018-05-01

    In order to obtain detailed information from multiple telescope observations a general blind super-resolution (SR) reconstruction approach for astronomical images is proposed in this paper. A pixel-reliability-based SR reconstruction algorithm is described and implemented, where the developed process incorporates flat field correction, automatic star searching and centering, iterative star matching, and sub-pixel image registration. Images captured by the 1-m telescope at Yunnan Observatory are used to test the proposed technique. The results of these experiments indicate that, following SR reconstruction, faint stars are more distinct, bright stars have sharper profiles, and the backgrounds have higher details; thus these results benefit from the high-precision star centering and image registration provided by the developed method. Application of the proposed approach not only provides more opportunities for new discoveries from astronomical image sequences, but will also contribute to enhancing the capabilities of most spatial or ground-based telescopes.

  20. National Astronomical Observatory of Japan

    CERN Document Server

    Haubold, Hans J; UN/ESA/NASA Workshop on the International Heliophysical Year 2007 and Basic Space Science, hosted by the National Astronomical Observatory of Japan

    2010-01-01

    This book represents Volume II of the Proceedings of the UN/ESA/NASA Workshop on the International Heliophysical Year 2007 and Basic Space Science, hosted by the National Astronomical Observatory of Japan, Tokyo, 18 - 22 June, 2007. It covers two programme topics explored in this and past workshops of this nature: (i) non-extensive statistical mechanics as applicable to astrophysics, addressing q-distribution, fractional reaction and diffusion, and the reaction coefficient, as well as the Mittag-Leffler function and (ii) the TRIPOD concept, developed for astronomical telescope facilities. The companion publication, Volume I of the proceedings of this workshop, is a special issue in the journal Earth, Moon, and Planets, Volume 104, Numbers 1-4, April 2009.

  1. Observatory Sponsoring Astronomical Image Contest

    Science.gov (United States)

    2005-05-01

    Forget the headphones you saw in the Warner Brothers thriller Contact, as well as the guttural throbs emanating from loudspeakers at the Very Large Array in that 1997 movie. In real life, radio telescopes aren't used for "listening" to anything - just like visible-light telescopes, they are used primarily to make images of astronomical objects. Now, the National Radio Astronomy Observatory (NRAO) wants to encourage astronomers to use radio-telescope data to make truly compelling images, and is offering cash prizes to winners of a new image contest. Radio Galaxy Fornax A Radio Galaxy Fornax A Radio-optical composite image of giant elliptical galaxy NGC 1316, showing the galaxy (center), a smaller companion galaxy being cannibalized by NGC 1316, and the resulting "lobes" (orange) of radio emission caused by jets of particles spewed from the core of the giant galaxy Click on image for more detail and images CREDIT: Fomalont et al., NRAO/AUI/NSF "Astronomy is a very visual science, and our radio telescopes are capable of producing excellent images. We're sponsoring this contest to encourage astronomers to make the extra effort to turn good images into truly spectacular ones," said NRAO Director Fred K.Y. Lo. The contest, offering a grand prize of $1,000, was announced at the American Astronomical Society's meeting in Minneapolis, Minnesota. The image contest is part of a broader NRAO effort to make radio astronomical data and images easily accessible and widely available to scientists, students, teachers, the general public, news media and science-education professionals. That effort includes an expanded image gallery on the observatory's Web site. "We're not only adding new radio-astronomy images to our online gallery, but we're also improving the organization and accessibility of the images," said Mark Adams, head of education and public outreach (EPO) at NRAO. "Our long-term goal is to make the NRAO Image Gallery an international resource for radio astronomy imagery

  2. Astronomical Data and Information Visualization

    Science.gov (United States)

    Goodman, Alyssa A.

    2010-01-01

    As the size and complexity of data sets increases, the need to "see" them more clearly increases as well. In the past, many scientists saw "fancy" data and information visualization as necessary for "outreach," but not for research. In this talk, I wlll demonstrate, using specific examples, why more and more scientists--not just astronomers--are coming to rely upon the development of new visualization strategies not just to present their data, but to understand it. Principal examples will be drawn from the "Astronomical Medicine" project at Harvard's Initiative in Innovative Computing, and from the "Seamless Astronomy" effort, which is co-sponsored by the VAO (NASA/NSF) and Microsoft Research.

  3. Astronomical optics and elasticity theory

    CERN Document Server

    Lemaitre, Gerard Rene

    2008-01-01

    Astronomical Optics and Elasticity Theory provides a very thorough and comprehensive account of what is known in this field. After an extensive introduction to optics and elasticity, the book discusses variable curvature and multimode deformable mirrors, as well as, in depth, active optics, its theory and applications. Further, optical design utilizing the Schmidt concept and various types of Schmidt correctors, as well as the elasticity theory of thin plates and shells are elaborated upon. Several active optics methods are developed for obtaining aberration corrected diffraction gratings. Further, a weakly conical shell theory of elasticity is elaborated for the aspherization of grazing incidence telescope mirrors. The very didactic and fairly easy-to-read presentation of the topic will enable PhD students and young researchers to actively participate in challenging astronomical optics and instrumentation projects.

  4. Far-infrared spectrophotometer for astronomical observations

    Science.gov (United States)

    Moseley, H.; Silverberg, R. F.

    1981-01-01

    A liquid-helium-cooled far infrared spectrophotometer was built and used to make low resolution observations of the continua of several kinds of astronomical objects using the Kuiper Airborne Observatory. This instrument fills a gap in both sensitivity to continuum sources and spectral resolution between the broadband photometers with lambda/Delta lambda approximately 1 and spectrometers with lambda/Delta lambda greater than 50. While designed primarily to study planetary nebulae, the instrument permits study of the shape of the continua of many weak sources which cannot easily be observed with high resolution systems.

  5. An infrared upconverter for astronomical imaging

    Science.gov (United States)

    Boyd, R. W.; Townes, C. H.

    1977-01-01

    An imaging upconverter has been constructed which is suitable for use in the study of the thermal 10-micron radiation from astronomical sources. The infrared radiation is converted to visible radiation by mixing in a 1-cm-long proustite crystal. The phase-matched 2-kayser bandpass is tunable from 9 to 11 microns. The conversion efficiency is 2 by 10 to the -7th power and the field of view of 40 arc seconds on the sky contains several hundred picture elements, approximately diffraction-limited resolution in a large telescope. The instrument has been used in studies of the sun, moon, Mercury, and VY Canis Majoris.

  6. Effect of Atorvastatin vs. Rosuvastatin on cardiac sympathetic nerve activity in non-diabetic patients with dilated cardiomyopathy

    Energy Technology Data Exchange (ETDEWEB)

    Tsutamoto, Takayoshi; Ibe, Kunihiro [Toyosato Hospital, Toyosato, Shiga (Japan); Sakai, Hiroshi; Yamaji, Masayuki; Kawahara, Chiho; Nakae, Ichiro; Fujii, Masanori; Yamamoto, Takashi; Horie, Minoru [Shiga Univ. of Medical Science, Faculty of Medicine, Otsu, Shiga (Japan)

    2011-08-15

    Effects of statin therapy on cardiac sympathetic nerve activity in patients with chronic heart failure (CHF) have not previously been evaluated. To compare the effects of lipophilic atorvastatin and hydrophilic rosuvastatin on cardiac sympathetic nerve activity in CHF patients with dilated cardiomyopathy (DCM), 63 stable outpatients with DCM, who were already receiving standard therapy for CHF, were randomized to atorvastatin (n=32) or rosuvastatin (n=31). We evaluated cardiac sympathetic nerve activity by cardiac {sup 123}I-metaiodobenzylguanidine (MIBG) scintigraphy, hemodynamic parameters and neurohumoral factors before and after 6 months of treatment. There were no differences in the baseline characteristics of the 2 groups. In the rosuvastatin group, there were no changes in MIBG parameters, left ventricular ejection fraction or plasma levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP) after 6 months of treatment. In contrast, the atorvastatin group showed a significant increase in the delayed heart/mediastinum count ratio (2.18{+-}0.4 vs. 2.36{+-}0.4, P<0.0001), and the washout rate was significantly decreased (34.8{+-}5.7 vs. 32.6{+-}6.3%, P=0.0001) after 6 months of treatment compared with the baseline values. The plasma NT-proBNP level was also significantly decreased (729{+-}858 vs. 558{+-}747 pg/ml, P=0.0139). Lipophilic atorvastatin but not hydrophilic rosuvastatin improves cardiac sympathetic nerve activity in CHF patients with DCM. (author)

  7. Rosuvastatin lowers coenzyme Q10 levels, but not mitochondrial adenosine triphosphate synthesis, in children with familial hypercholesterolemia

    NARCIS (Netherlands)

    Avis, Hans J.; Hargreaves, Ian P.; Ruiter, Jos P. N.; Land, John M.; Wanders, Ronald J.; Wijburg, Frits A.

    2011-01-01

    To investigate whether statin therapy affects coenzyme Q10 (CoQ10) status in children with heterozygous familial hypercholesterolemia (FH). Samples were obtained at baseline (treatment naïve) and after dose titration with rosuvastatin, aiming for a low-density lipoprotein cholesterol level of 110

  8. Effect of rosuvastatin intensification therapy on blood lipid metabolism, adipocytokines and plaque stability after PCI in ACS patients

    Directory of Open Access Journals (Sweden)

    Xiu-Quan Sun

    2017-10-01

    Full Text Available Objective: To explore the effect of rosuvastatin intensification therapy on blood lipid metabolism, adipocytokines and plaque stability after PCI in ACS patients. Methods: ACS patients who received PCI in the hospital between July 2015 and January 2017were reviewed and divided into the routine dose group (n=60 who received rosuvastatin routine dose therapy after PCI and the intensification therapy group (n=46 who received rosuvastatin intensification therapy after PCI. The differences in blood lipid metabolism, adipocytokines and plaque stability were compared between the two groups before and after treatment. Results: Before PCI, the differences in blood lipid metabolism, adipocytokines and plaque stability were not statistically significant between the two groups. 1 month after PCI, lipid metabolism indexes HDL-C and ApoA1 levels in peripheral blood of intensification therapy group were higher than those of routine dose group while LDL-C and ApoB levels were lower than those of routine dose group; adipocytokines APN and Leptin levels in serum were higher than those of routine dose group while Resistin level was lower than that of routine dose group; plaque stability- related indexes ICAM-1, MMP-1 and TIMP-1 levels were lower than those of routine dose group. Conclusion: Rosuvastatin intensification therapy after PCI could effectively regulate the lipid metabolism and increase the plaque stability in ACS patients.

  9. Visualizing Astronomical Data with Blender

    Science.gov (United States)

    Kent, Brian R.

    2014-01-01

    We present methods for using the 3D graphics program Blender in the visualization of astronomical data. The software's forte for animating 3D data lends itself well to use in astronomy. The Blender graphical user interface and Python scripting capabilities can be utilized in the generation of models for data cubes, catalogs, simulations, and surface maps. We review methods for data import, 2D and 3D voxel texture applications, animations, camera movement, and composite renders. Rendering times can be improved by using graphic processing units (GPUs). A number of examples are shown using the software features most applicable to various kinds of data paradigms in astronomy.

  10. Focus on astronomical predictable events

    DEFF Research Database (Denmark)

    Jacobsen, Aase Roland

    2006-01-01

    At the Steno Museum Planetarium we have for many occasions used a countdown clock to get focus om astronomical events. A countdown clock can provide actuality to predictable events, for example The Venus Transit, Opportunity landing on Mars and The Solar Eclipse. The movement of the clock attracs...... the public and makes a point of interest in a small exhibit area. A countdown clock can be simple, but it is possible to expand the concept to an eye-catching part of a museum....

  11. Strasbourg Astronomical Data Center (CDS

    Directory of Open Access Journals (Sweden)

    F Genova

    2013-01-01

    Full Text Available The Centre de Donnees astronomiques de Strasbourg (CDS, created in 1972, has been a pioneer in the dissemination of digital scientific data. Ensuring sustainability for several decades has been a major issue because science and technology evolve continuously and the data flow increases endlessly. The paper briefly describes CDS activities, major services, and its R&D strategy to take advantage of new technologies. The next frontiers for CDS are the new Web 2.0/3.0 paradigm and, at a more general level, global interoperability of astronomical on-line resources in the Virtual Observatory framework.

  12. astroplan: Observation Planning for Astronomers

    Science.gov (United States)

    Morris, Brett

    2016-03-01

    Astroplan is an observation planning package for astronomers. It is an astropy-affiliated package which began as a Google Summer of Code project. Astroplan facilitates convenient calculation of common observational quantities, like target altitudes and azimuths, airmasses, and rise/set times. Astroplan also computes when targets are observable given various extensible observing constraints, for example: within a range of airmasses or altitudes, or at a given separation from the Moon. Astroplan is taught in the undergraduate programming for astronomy class, and enables observational Pre- MAP projects at the University of Washington. In the near future, we plan to implement scheduling capabilities in astroplan on top of the constraints framework.

  13. The Victorian Amateur Astronomer: Independent Astronomical Research in Britain 1820-1920

    Science.gov (United States)

    Chapman, Allan

    1999-01-01

    This is the first book to look in detail at amateur astronomy in Victorian Britain. It deals with the technical issues that were active in Victorian astronomy, and reviews the problems of finance, patronage and the dissemination of scientific ideas. It also examines the relationship between the amateur and professional in Britain. It contains a wealth of previously unpublished biographical and anecdotal material, and an extended bibliography with notes incorporating much new scholarship. In The Victorian Amateur Astronomer, Allan Chapman shows that while on the continent astronomical research was lavishly supported by the state, in Britain such research was paid for out of the pockets of highly educated, wealthy gentlemen the so-called Grand Amateurs . It was these powerful individuals who commissioned the telescopes, built the observatories, ran the learned societies, and often stole discoveries from their state-employed colleagues abroad. In addition to the Grand Amateurs , Victorian Britain also contained many self-taught amateurs. Although they belonged to no learned societies, these people provide a barometer of the popularity of astronomy in that age. In the late 19th century, the comfortable middle classes clergymen, lawyers, physicians and retired military officers took to astronomy as a serious hobby. They formed societies which focused on observation, lectures and discussions, and it was through this medium that women first came to play a significant role in British astronomy. Readership: Undergraduate and postgraduate students studying the history of science or humanities, professional historians of science, engineering and technology, particularly those with an interest in astronomy, the development of astronomical ideas, scientific instrument makers, and amateur astronomers.

  14. Explanatory supplement to the astronomical almanac

    CERN Document Server

    Urban, Sean E

    2013-01-01

    The Explanatory Supplement to the Astronomical Almanac offers explanatory material, supplemental information and detailed descriptions of the computational models and algorithms used to produce The Astronomical Almanac, which is an annual publication prepared jointly by the US Naval Observatory and Her Majesty's Nautical Almanac Office in the UK. Like The Astronomical Almanac, The Explanatory Supplement provides detailed coverage of modern positional astronomy. Chapters are devoted to the celestial and terrestrial reference frames, orbital ephemerides, precession, nutation, Earth rotation, and coordinate transformations. These topics have undergone substantial revisions since the last edition was published. Astronomical positions are intertwined with timescales and relativity in The Astronomical Almanac, so related chapters are provided in The Explanatory Supplement. The Astronomical Almanac also includes information on lunar and solar eclipses, physical ephemerides of solar system bodies, and calendars, so T...

  15. SAADA: Astronomical Databases Made Easier

    Science.gov (United States)

    Michel, L.; Nguyen, H. N.; Motch, C.

    2005-12-01

    Many astronomers wish to share datasets with their community but have not enough manpower to develop databases having the functionalities required for high-level scientific applications. The SAADA project aims at automatizing the creation and deployment process of such databases. A generic but scientifically relevant data model has been designed which allows one to build databases by providing only a limited number of product mapping rules. Databases created by SAADA rely on a relational database supporting JDBC and covered by a Java layer including a lot of generated code. Such databases can simultaneously host spectra, images, source lists and plots. Data are grouped in user defined collections whose content can be seen as one unique set per data type even if their formats differ. Datasets can be correlated one with each other using qualified links. These links help, for example, to handle the nature of a cross-identification (e.g., a distance or a likelihood) or to describe their scientific content (e.g., by associating a spectrum to a catalog entry). The SAADA query engine is based on a language well suited to the data model which can handle constraints on linked data, in addition to classical astronomical queries. These constraints can be applied on the linked objects (number, class and attributes) and/or on the link qualifier values. Databases created by SAADA are accessed through a rich WEB interface or a Java API. We are currently developing an inter-operability module implanting VO protocols.

  16. The League of Astronomers: Outreach

    Science.gov (United States)

    Paat, Anthony; Brandel, A.; Schmitz, D.; Sharma, R.; Thomas, N. H.; Trujillo, J.; Laws, C. S.; Astronomers, League of

    2014-01-01

    The University of Washington League of Astronomers (LOA) is an organization comprised of University of Washington (UW) undergraduate students. Our main goal is to share our interest in astronomy with the UW community and with the general public. The LOA hosts star parties on the UW campus and collaborates with the Seattle Astronomical Society (SAS) on larger Seattle-area star parties. At the star parties, we strive to teach our local community about what they can view in our night sky. LOA members share knowledge of how to locate constellations and use a star wheel. The relationship the LOA has with members of SAS increases both the number of events and people we are able to reach. Since the cloudy skies of the Northwest prevent winter star parties, we therefore focus our outreach on the UW Mobile Planetarium, an inflatable dome system utilizing Microsoft’s WorldWide Telescope (WWT) software. The mobile planetarium brings astronomy into the classrooms of schools unable to travel to the UW on-campus planetarium. Members of the LOA volunteer their time towards this project and we make up the majority of the Mobile Planetarium volunteers. Our outreach efforts allow us to connect with the community and enhance our own knowledge of astronomy.

  17. Astronomers in the Chemist's War

    Science.gov (United States)

    Trimble, Virginia L.

    2012-01-01

    World War II, with radar, rockets, and "atomic" bombs was the physicists' war. And many of us know, or think we know, what our more senior colleagues did during it, with Hubble and Hoffleit at Aberdeen; M. Schwarzschild on active duty in Italy; Bondi, Gold, and Hoyle hunkered down in Dunsfeld, Surrey, talking about radar, and perhaps steady state; Greenstein and Henyey designing all-sky cameras; and many astronomers teaching navigation. World War I was The Chemists' War, featuring poison gases, the need to produce liquid fuels from coal on one side of the English Channel and to replace previously-imported dyesstuffs on the other. The talke will focus on what astronomers did and had done to them between 1914 and 1919, from Freundlich (taken prisoner on an eclipse expedition days after the outbreak of hostilities) to Edwin Hubble, returning from France without ever having quite reached the front lines. Other events bore richer fruit (Hale and the National Research Council), but very few of the stories are happy ones. Most of us have neither first nor second hand memories of The Chemists' War, but I had the pleasure of dining with a former Freundlich student a couple of weeks ago.

  18. Amateur Astronomers: Secret Agents of EPO

    Science.gov (United States)

    Berendsen, M.; White, V.; Devore, E.; Reynolds, M.

    2008-06-01

    Amateur astronomers prime the public to be more interested, receptive, and excited about space science, missions, and programs. Through recent research and targeted programs, amateur astronomy outreach is being increasingly recognized by professional astronomers, educators, and other amateurs as a valued and important service. The Night Sky Network program, administered by the ASP, is the first nationwide research-based program specifically targeted to support outreach by amateur astronomers. This Network of trained and informed amateur astronomers can provide a stimulating introduction to your EPO programs as Network members share the night sky with families, students, and youth groups.

  19. Astronomical Symbolism in Australian Aboriginal Rock Art

    Science.gov (United States)

    Norris, Ray P.; Hamacher, Duane W.

    2011-05-01

    Traditional Aboriginal Australian cultures include a significant astronomical component, perpetuated through oral tradition and ceremony. This knowledge has practical navigational and calendrical functions, and sometimes extends to a deep understanding of the motion of objects in the sky. Here we explore whether this astronomical tradition is reflected in the rock art of Aboriginal Australians. We find several plausible examples of depictions of astronomical figures and symbols, and also evidence that astronomical observations were used to set out stone arrangements. However, we recognise that the case is not yet strong enough to make an unequivocal statement, and describe our plans for further research.

  20. Storing Astronomical Information on the Romanian Territory

    Science.gov (United States)

    Stavinschi, M.; Mioc, V.

    2004-12-01

    Romanian astronomy has a more than 2000-year old tradition, which is, however, little known abroad. The first known archive of astronomical information is the Dacian sanctuary at Sarmizegetusa Regia, erected in the first century AD, having similarities with that of Stonehenge. After a gap of more than 1000 years, more sources of astronomical information become available, mainly records of astronomical events. Monasteries were the safest storage places of these genuine archives. We present a classification of the ways of storing astronomical information, along with characteristic examples.

  1. FITSManager: Management of Personal Astronomical Data

    Science.gov (United States)

    Cui, Chenzhou; Fan, Dongwei; Zhao, Yongheng; Kembhavi, Ajit; He, Boliang; Cao, Zihuang; Li, Jian; Nandrekar, Deoyani

    2011-07-01

    With the increase of personal storage capacity, it is easy to find hundreds to thousands of FITS files in the personal computer of an astrophysicist. Because Flexible Image Transport System (FITS) is a professional data format initiated by astronomers and used mainly in the small community, data management toolkits for FITS files are very few. Astronomers need a powerful tool to help them manage their local astronomical data. Although Virtual Observatory (VO) is a network oriented astronomical research environment, its applications and related technologies provide useful solutions to enhance the management and utilization of astronomical data hosted in an astronomer's personal computer. FITSManager is such a tool to provide astronomers an efficient management and utilization of their local data, bringing VO to astronomers in a seamless and transparent way. FITSManager provides fruitful functions for FITS file management, like thumbnail, preview, type dependent icons, header keyword indexing and search, collaborated working with other tools and online services, and so on. The development of the FITSManager is an effort to fill the gap between management and analysis of astronomical data.

  2. Comparison of Low-Dose Rosuvastatin with Atorvastatin in Lipid-Lowering Efficacy and Safety in a High-Risk Pakistani Cohort: An Open-Label Randomized Trial

    Directory of Open Access Journals (Sweden)

    Abdul Rehman Arshad

    2014-01-01

    Full Text Available Background. Treatment of hyperlipidemia is helpful in both primary and secondary prevention of coronary heart disease and stroke. Aim. To compare lipid-lowering efficacy of rosuvastatin with atorvastatin. Methodology. This open-label randomized controlled trial was carried out at 1 Mountain Medical Battalion from September 2012 to August 2013 on patients with type 2 diabetes, hypertension, myocardial infarction, or stroke, meriting treatment with a statin. Those with secondary causes of dyslipidemia were excluded. Blood samples for estimation of serum total cholesterol, triglycerides, HDL-C, and LDL-C were collected after a 12-hour fast. Patients were randomly allocated to receive either atorvastatin 10 mg HS or rosuvastatin 5 mg HS daily. Lipid levels were rechecked after six weeks. Results. Atorvastatin was used in 63 patients and rosuvastatin in 66. There was a greater absolute and percent reduction in serum LDL-C levels with rosuvastatin as compared to atorvastatin (0.96 versus 0.54 mg/dL; P=0.011 and 24.34 versus 13.66%; P=0.045, whereas reduction in all other fractions was equal. Myalgias were seen in 5 (7.94% patients treated with atorvastatin and 8 (12.12% patients treated with rosuvastatin (P: 0.432. Conclusion. Rosuvastatin produces a greater reduction in serum LDL-C levels and should therefore be preferred over atorvastatin.

  3. Astronomical Alignments in a Neolithic Chinese Site?

    Science.gov (United States)

    Nelson, S.; Stencel, R. E.

    1997-12-01

    In the Manchurian province of Liaoning, near 41N19' and 119E30', exist ruins of a middle Neolithic society (2500 to 4000 BC) known as the Hongshan culture. This location, called Niuheliang, is comprised of 16 locations with monumental structures scattered over 80 square kilometers of hills. Most are stone burial structures that contain jade artifacts implying wealth and power. One structure is unique in being unusually shaped and containing oversized effigies of goddess figures. This structure also has a commanding view of the surrounding landscape. The presence of decorated pottery, jade and worked copper suggests the Hongshan people were sophisticated artisans and engaged in long-distance trading. During 1997, we've conducted a course at Denver as part of our Core Curriculum program for upper division students, that has examined the astronomical and cultural aspects of the Niuheliang site, to attempt to determine whether these contemporaries of the builders of Stonehenge may have included astronomical alignments into their constructions. The preliminary result of our studies suggests that certain monuments have potential for lunar standstill observation from the "goddess temple". For updates on these results, please see our website: www.du.edu/ rstencel/core2103.html.

  4. Large Astronomical Surveys, Catalogs and Databases

    Directory of Open Access Journals (Sweden)

    Mickaelian A. M.

    2012-09-01

    Full Text Available We review the status of all-sky and large astronomical surveys and their catalogued data over the whole range of electromagnetic spectrum, from gamma-ray to radio, such as ROSAT in X-ray, GALEX in UV, SDSS and several POSS1/2 based catalogs (APM, MAPS, USNO, GSC in optical, 2MASS and WISE in NIR, IRAS and AKARI in MIR/FIR, NVSS and FIRST in radio range and others. Present astronomical archives contain billions of objects, Galactic as well as extragalactic, and the vast amount of data in them permit new studies and discoveries. Cross-correlations result in revealing new objects and new samples. Very often, dozens of thousands of sources hide a few very interesting ones that are needed to be discovered by comparison of various physical characteristics. Most of the modern databases currently provide VO access to the stored information. This permits not only open access but also fast analysis and managing of these data.

  5. Sketching the moon an astronomical artist's guide

    CERN Document Server

    Handy, Richard; McCague, Thomas; Rix, Erika; Russell, Sally

    2012-01-01

    Soon after you begin studying the sky through your small telescope or binoculars, you will probably be encouraged by others to make sketches of what you see. Sketching is a time-honored tradition in amateur astronomy and dates back to the earliest times, when telescopes were invented. Even though we have lots of new imaging technologies nowadays, including astrophotography, most observers still use sketching to keep a record of what they see, make them better observers, and in hopes of perhaps contributing something to the body of scientific knowledge about the Moon. Some even sketch because it satisfies their artistic side. The Moon presents some unique challenges to the astronomer-artist, the Moon being so fond of tricks of the light. Sketching the Moon: An Astronomical Artist’s Guide, by five of the best lunar observer-artists working today, will guide you along your way and help you to achieve really high-quality sketches. All the major types of lunar features are covered, with a variety of sketching te...

  6. Powerful Radio Burst Indicates New Astronomical Phenomenon

    Science.gov (United States)

    2007-09-01

    Astronomers studying archival data from an Australian radio telescope have discovered a powerful, short-lived burst of radio waves that they say indicates an entirely new type of astronomical phenomenon. Region of Strong Radio Burst Visible-light (negative greyscale) and radio (contours) image of Small Magellanic Cloud and area where burst originated. CREDIT: Lorimer et al., NRAO/AUI/NSF Click on image for high-resolution file ( 114 KB) "This burst appears to have originated from the distant Universe and may have been produced by an exotic event such as the collision of two neutron stars or the death throes of an evaporating black hole," said Duncan Lorimer, Assistant Professor of Physics at West Virginia University (WVU) and the National Radio Astronomy Observatory (NRAO). The research team led by Lorimer consists of Matthew Bailes of Swinburne University in Australia, Maura McLaughlin of WVU and NRAO, David Narkevic of WVU, and Fronefield Crawford of Franklin and Marshall College in Lancaster, Pennsylvania. The astronomers announced their findings in the September 27 issue of the online journal Science Express. The startling discovery came as WVU undergraduate student David Narkevic re-analyzed data from observations of the Small Magellanic Cloud made by the 210-foot Parkes radio telescope in Australia. The data came from a survey of the Magellanic Clouds that included 480 hours of observations. "This survey had sought to discover new pulsars, and the data already had been searched for the type of pulsating signals they produce," Lorimer said. "We re-examined the data, looking for bursts that, unlike the usual ones from pulsars, are not periodic," he added. The survey had covered the Magellanic Clouds, a pair of small galaxies in orbit around our own Milky Way Galaxy. Some 200,000 light-years from Earth, the Magellanic Clouds are prominent features in the Southern sky. Ironically, the new discovery is not part of these galaxies, but rather is much more distant

  7. Astronomical theory of climate change

    Energy Technology Data Exchange (ETDEWEB)

    Berger, A.; Loutre, M.F. [Universite Catholique de Louvain (UCL), Louvain-la-Neuve (Belgium). Inst. d' Astronomie et de Geophysique G. Lemaitre

    2004-12-01

    The astronomical theory of paleo-climates aims to explain the climatic variations occurring with quasi-periodicities lying between tens and hundreds of thousands of years. The origin of these quasi-cycles lies in the astronomically driven changes in the latitudinal and seasonal distributions of the energy that the Earth receives from the Sun. These changes are then amplified by the feedback mechanisms which characterize the natural behaviour of the climate system like those involving the albedo-, the water vapor-, and the vegetation- temperature relationships. Climate models of different complexities are used to explain the chain of processes which finally link the long-term variations of three astronomical parameters to the long-term climatic variations at time scale of tens to hundreds of thousands of years. In particular, sensitivity analysis to the astronomically driven insolation changes and to the CO{sub 2} atmospheric concentrations have been performed with the 2-dimension climate model of Louvain-la-Neuve. It could be shown that this model simulates more or less correctly the entrance into glaciation around 2.75 million year (Myr) BP (before present), the late Pliocene-early Pleistocene 41-kyr (thousand years) cycle, the emergence of the 100-kyr cycle around 850 kyr BP and the glacial-interglacial cycles of the last 600 kyr. During the Late Pliocene (in an ice-free - warm world) ice sheets can only develop during times of sufficiently low summer insolation. This occurs during large eccentricity times when climatic precession and obliquity combine to obtain such low values, leading to the 41-kyr period between 3 and 1 million years BP. On the contrary in a glacial world, ice sheets persist most of the time except when insolation is very high in polar latitudes, requiring large eccentricity again, but leading this time to interglacial and finally to the 100-kyr period of the last 1 Myr. Using CO{sub 2} scenarios, it has been shown that stage 11 and stage 1

  8. Asteroids astronomical and geological bodies

    CERN Document Server

    Burbine, Thomas H

    2016-01-01

    Asteroid science is a fundamental topic in planetary science and is key to furthering our understanding of planetary formation and the evolution of the Solar System. Ground-based observations and missions have provided a wealth of new data in recent years, and forthcoming missions promise further exciting results. This accessible book presents a comprehensive introduction to asteroid science, summarising the astronomical and geological characteristics of asteroids. The interdisciplinary nature of asteroid science is reflected in the broad range of topics covered, including asteroid and meteorite classification, chemical and physical properties of asteroids, observational techniques, cratering, and the discovery of asteroids and how they are named. Other chapters discuss past, present and future space missions and the threat that these bodies pose for Earth. Based on an upper-level course on asteroids and meteorites taught by the author, this book is ideal for students, researchers and professional scientists ...

  9. Preparing Colorful Astronomical Images II

    Science.gov (United States)

    Levay, Z. G.; Frattare, L. M.

    2002-12-01

    We present additional techniques for using mainstream graphics software (Adobe Photoshop and Illustrator) to produce composite color images and illustrations from astronomical data. These techniques have been used on numerous images from the Hubble Space Telescope to produce photographic, print and web-based products for news, education and public presentation as well as illustrations for technical publication. We expand on a previous paper to present more detail and additional techniques, taking advantage of new or improved features available in the latest software versions. While Photoshop is not intended for quantitative analysis of full dynamic range data (as are IRAF or IDL, for example), we have had much success applying Photoshop's numerous, versatile tools to work with scaled images, masks, text and graphics in multiple semi-transparent layers and channels.

  10. IAU Public Astronomical Organisations Network

    Science.gov (United States)

    Canas, Lina; Cheung, Sze Leung

    2015-08-01

    The Office for Astronomy Outreach has devoted intensive means to create and support a global network of public astronomical organisations around the world. Focused on bringing established and newly formed amateur astronomy organizations together, providing communications channels and platforms for disseminating news to the global community and the sharing of best practices and resources among these associations around the world. In establishing the importance that these organizations have for the dissemination of activities globally and acting as key participants in IAU various campaigns social media has played a key role in keeping this network engaged and connected. Here we discuss the implementation process of maintaining this extensive network, the processing and gathering of information and the interactions between local active members at a national and international level.

  11. Astronomical Data in Undergraduate courses

    Science.gov (United States)

    Clarkson, William I.; Swift, Carrie; Hughes, Kelli; Burke, Christopher J. F.; Burgess, Colin C.; Elrod, Aunna V.; Howard, Brittany; Stahl, Lucas; Matzke, David; Bord, Donald J.

    2016-06-01

    We present status and plans for our ongoing efforts to develop data analysis and problem-solving skills through Undergraduate Astronomy instruction. While our initiatives were developed with UM-Dearborn’s student body primarily in mind, they should be applicable for a wide range of institution and of student demographics. We focus here on two strands of our effort.Firstly, students in our Introductory Astronomy (ASTR 130) general-education course now perform several “Data Investigations”, in which they interrogate the Hubble Legacy Archive to illustrate important course concepts. This was motivated in part by the realization that typical public data archives now include tools to interrogate the observations that are sufficiently accessible that introductory astronomy students can use them to perform real science, albeit mostly at a descriptive level. We are continuing to refine these investigations, and, most importantly, to critically assess their effectiveness in terms of the student learning outcomes we wish to achieve. This work is supported by grant HST-EO-13758, provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555.Secondly, at the advanced-undergraduate level, students taking courses in our Astronomy minor are encouraged to gain early experience in techniques of astronomical observation and analysis that are used by professionals. We present two example projects from the Fall 2015 iteration of our upper-division course ASTR330 (The Cosmic Distance Ladder), one involving Solar System measurements, the second producing calibrated aperture photometry. For both projects students conducted, analysed, and interpreted observations using our 0.4m campus telescope, and used many of the same analysis tools as professional astronomers. This work is supported partly from a Research Initiation and Seed grant from the

  12. Factors Contributing to Lifelong Science Learning: Amateur Astronomers and Birders

    Science.gov (United States)

    Jones, M. Gail; Corin, Elysa Nicole; Andre, Thomas; Childers, Gina M.; Stevens, Vanessa

    2017-01-01

    This research examined lifelong science learning reported by amateur astronomers and birders. One hundred seven adults who reported engaging in an informal (out-of-school) science interest were interviewed as part of an ongoing series of studies of lifelong science learners. The goal of the study was to gain insight into how and why amateur…

  13. Solubility of rosuvastatin calcium in different neat solvents at different temperatures

    International Nuclear Information System (INIS)

    Alshora, Doaa H.; Haq, Nazrul; Alanazi, Fars K.; Ibrahim, Mohamed A.; Shakeel, Faiyaz

    2016-01-01

    Highlights: • Solubility of rosuvastatin calcium (ROSCa) in seven neat solvents was determined. • The solubility of ROSCa was recorded highest in propylene glycol. • Experimental solubilities were correlated with Apelblat and ideal models. • Good correlation was existed between experimental and calculated solubilities. - Abstract: In the current research work, the solubility of rosuvastatin calcium (ROSCa) in seven different neat solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), isopropyl alcohol (IPA) and propane-1,2-diol (PG) was measured at five different temperatures i.e. T = (298.15 to 318.15) K and atmospheric pressure. Values of the experimental solubility of ROSCa were correlated with Apelblat and ideal models which showed good correlation and model fitting. The solubility (as mole fraction) of ROSCa was recorded highest in PG (1.89 · 10"−"2 at T = 318.15 K) followed by 1-butanol (8.20 · 10"−"4 at T = 318.15 K), ethanol (6.81 · 10"−"4 at T = 318.15 K), IPA (5.66 · 10"−"4 at T = 318.15 K), EG (5.03 · 10"−"4 at T = 318.15 K), 2-butanol (1.08 · 10"−"4 at T = 318.15 K) and water (1.40 · 10"−"5 at T = 318.15 K). The experimental results from this research work would be helpful in the development of conventional and advanced liquid dosage forms of ROSCa.

  14. Rosuvastatin ameliorates inflammation, renal fat accumulation, and kidney injury in transgenic spontaneously hypertensive rats expressing human C-reactive protein

    Czech Academy of Sciences Publication Activity Database

    Šilhavý, Jan; Zídek, Václav; Landa, Vladimír; Šimáková, Miroslava; Mlejnek, Petr; Oliyarnyk, O.; Malínská, H.; Kazdová, L.; Mancini, M.; Pravenec, Michal

    2015-01-01

    Roč. 64, č. 3 (2015), s. 295-301 ISSN 0862-8408 R&D Projects: GA MŠk(CZ) LH11049; GA MŠk(CZ) LL1204; GA MZd(CZ) NT14325; GA ČR(CZ) GB14-36804G Institutional support: RVO:67985823 Keywords : rosuvastatin * kidney damage * CRP * transgenic * spontaneously hypertensive rat Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.643, year: 2015

  15. Leslie Peltier, Amateur Astronomer and Observer Extraordinaire

    Science.gov (United States)

    Corbin, B. G.

    2003-12-01

    Leslie Copus Peltier, (Jan. 2, 1900-May 10, 1980) was called "the world's greatest non-professional astronomer" by none other than Harlow Shapley, and also referred to as the "the world's greatest living amateur astronomer". He began observing variable stars on March 1, 1918 with an observation of R. Leonis and at the time of his death had made a total of 132,123 observations of variable stars. These were reported to the AAVSO on a consecutive monthly basis stretching from 1918 to his death in 1980. As of October 2003, he was still on AAVSO's list of the top 25 observers in its history. Born on a farm near Delphos, Ohio, his parents were well read and their home was filled with books on different subjects, including nature guides. As a young man he studied the flora and fauna of the area and in 1915 began his study of the heavens with Vega being the first star he identified. After the purchase of a 2-inch spyglass, his observations of variable stars began to be noticed by professional astronomers and the AAVSO loaned him a 4-inch Mogey refractor; shortly thereafter Henry Norris Russell of Princeton loaned him via the AAVSO a 6-inch refractor, a comet seeker of short focus. He discovered 12 comets, 10 of which carry his name, and 6 novae or recurring novae. His design of the "Merry-Go-Round Observatory" was a novel approach with the whole observatory revolving around the observer while seated in his observing chair. Miami University (Ohio) later donated to him their 12-inch Clark refractor with its dome. His first book, Starlight Nights: The Adventures of a Star-Gazer, appeared in 1965. This autobiography, an ode to the joys of observing both the night sky and nature, was written in beautifully descriptive language that helped lead countless readers into astronomy. Departing from astronomy, in 1977 he published The Place on Jennings Creek. Written in the style of the 19th century naturalist, the book was devoted to his family's home, Brookhaven, and its natural

  16. Reporting Astronomical Discoveries: Past, Now, and Future

    Science.gov (United States)

    Yamaoka, Hitoshi; Green, Daniel W. E.; Samus, Nikolai N.; West, Richard

    2015-08-01

    Many new astronomical objects have been discovered over the years by amateur astronomers, and this continues to be the case. They have traditionally reported them (as have professional astronomers) to the Central Bureau for Astronomical Telegrams (CBAT), which was established in the 19th century. This procedure has worked very well throughout the 20th century, moving under the umbrella of the newly established IAU in 1920. The discoverers have been honored by the formal announcement of their discoveries in the publications of the CBAT.In recent years, some professional research groups have established other ways of announcing their discoveries of explosive objects such as novae and supernovae; some do not now report their discoveries or spectroscopic confirmations of the transients to the CBAT, including often spectroscopic reports of objects posted to the CBAT "Transient Objects Confirmation Page" -- the highly successful TOCP webpage, which assigns official positional designations to new transients posted there by approved, registered users. This leads to a delay in formal announcements of discoveries by amateur astronomers in many cases, as well as inconsistent designations being put into use by individual groups. Amateur astronomers are feeling frustrated about this situation, and they hope that the IAU will help to settle the situation.We have proposed the new IAU commission NC-52, which will treat these phenomena in a continuation of Commission 6, through the CBAT. We hope to continuously support the reporting of the discoveries by amateur astronomers, as well as professional astronomers, who all deserve and desire proper recognition. Our strategy will maintain the firm trust between the amateur and professional astronomers, which is necessary for true collaboration. The plan is for the CBAT to work with collaborators to assure that discoveries posted on the TOCP are promptly designated and announced by the CBAT, even when confirmations are made elsewhere

  17. VEGAS: VErsatile GBT Astronomical Spectrometer

    Science.gov (United States)

    Bussa, Srikanth; VEGAS Development Team

    2012-01-01

    The National Science Foundation Advanced Technologies and Instrumentation (NSF-ATI) program is funding a new spectrometer backend for the Green Bank Telescope (GBT). This spectrometer is being built by the CICADA collaboration - collaboration between the National Radio Astronomy Observatory (NRAO) and the Center for Astronomy Signal Processing and Electronics Research (CASPER) at the University of California Berkeley.The backend is named as VErsatile GBT Astronomical Spectrometer (VEGAS) and will replace the capabilities of the existing spectrometers. This backend supports data processing from focal plane array systems. The spectrometer will be capable of processing up to 1.25 GHz bandwidth from 8 dual polarized beams or a bandwidth up to 10 GHz from a dual polarized beam.The spectrometer will be using 8-bit analog to digital converters (ADC), which gives a better dynamic range than existing GBT spectrometers. There will be 8 tunable digital sub-bands within the 1.25 GHz bandwidth, which will enhance the capability of simultaneous observation of multiple spectral transitions. The maximum spectral dump rate to disk will be about 0.5 msec. The vastly enhanced backend capabilities will support several science projects with the GBT. The projects include mapping temperature and density structure of molecular clouds; searches for organic molecules in the interstellar medium; determination of the fundamental constants of our evolving Universe; red-shifted spectral features from galaxies across cosmic time and survey for pulsars in the extreme gravitational environment of the Galactic Center.

  18. Astronomical Surveys and Big Data

    Directory of Open Access Journals (Sweden)

    Mickaelian Areg M.

    2016-03-01

    Full Text Available Recent all-sky and large-area astronomical surveys and their catalogued data over the whole range of electromagnetic spectrum, from γ-rays to radio waves, are reviewed, including such as Fermi-GLAST and INTEGRAL in γ-ray, ROSAT, XMM and Chandra in X-ray, GALEX in UV, SDSS and several POSS I and POSS II-based catalogues (APM, MAPS, USNO, GSC in the optical range, 2MASS in NIR, WISE and AKARI IRC in MIR, IRAS and AKARI FIS in FIR, NVSS and FIRST in radio range, and many others, as well as the most important surveys giving optical images (DSS I and II, SDSS, etc., proper motions (Tycho, USNO, Gaia, variability (GCVS, NSVS, ASAS, Catalina, Pan-STARRS, and spectroscopic data (FBS, SBS, Case, HQS, HES, SDSS, CALIFA, GAMA. An overall understanding of the coverage along the whole wavelength range and comparisons between various surveys are given: galaxy redshift surveys, QSO/AGN, radio, Galactic structure, and Dark Energy surveys. Astronomy has entered the Big Data era, with Astrophysical Virtual Observatories and Computational Astrophysics playing an important role in using and analyzing big data for new discoveries.

  19. Astronomers Gain Clues About Fundamental Physics

    Science.gov (United States)

    2005-12-01

    An international team of astronomers has looked at something very big -- a distant galaxy -- to study the behavior of things very small -- atoms and molecules -- to gain vital clues about the fundamental nature of our entire Universe. The team used the National Science Foundation's Robert C. Byrd Green Bank Telescope (GBT) to test whether the laws of nature have changed over vast spans of cosmic time. The Green Bank Telescope The Robert C. Byrd Green Bank Telescope CREDIT: NRAO/AUI/NSF (Click on image for GBT gallery) "The fundamental constants of physics are expected to remain fixed across space and time; that's why they're called constants! Now, however, new theoretical models for the basic structure of matter indicate that they may change. We're testing these predictions." said Nissim Kanekar, an astronomer at the National Radio Astronomy Observatory (NRAO), in Socorro, New Mexico. So far, the scientists' measurements show no change in the constants. "We've put the most stringent limits yet on some changes in these constants, but that's not the end of the story," said Christopher Carilli, another NRAO astronomer. "This is the exciting frontier where astronomy meets particle physics," Carilli explained. The research can help answer fundamental questions about whether the basic components of matter are tiny particles or tiny vibrating strings, how many dimensions the Universe has, and the nature of "dark energy." The astronomers were looking for changes in two quantities: the ratio of the masses of the electron and the proton, and a number physicists call the fine structure constant, a combination of the electron charge, the speed of light and the Planck constant. These values, considered fundamental physical constants, once were "taken as time independent, with values given once and forever" said German particle physicist Christof Wetterich. However, Wetterich explained, "the viewpoint of modern particle theory has changed in recent years," with ideas such as

  20. Old Star's "Rebirth" Gives Astronomers Surprises

    Science.gov (United States)

    2005-04-01

    Astronomers using the National Science Foundation's Very Large Array (VLA) radio telescope are taking advantage of a once-in-a-lifetime opportunity to watch an old star suddenly stir back into new activity after coming to the end of its normal life. Their surprising results have forced them to change their ideas of how such an old, white dwarf star can re-ignite its nuclear furnace for one final blast of energy. Sakurai's Object Radio/Optical Images of Sakurai's Object: Color image shows nebula ejected thousands of years ago. Contours indicate radio emission. Inset is Hubble Space Telescope image, with contours indicating radio emission; this inset shows just the central part of the region. CREDIT: Hajduk et al., NRAO/AUI/NSF, ESO, StSci, NASA Computer simulations had predicted a series of events that would follow such a re-ignition of fusion reactions, but the star didn't follow the script -- events moved 100 times more quickly than the simulations predicted. "We've now produced a new theoretical model of how this process works, and the VLA observations have provided the first evidence supporting our new model," said Albert Zijlstra, of the University of Manchester in the United Kingdom. Zijlstra and his colleagues presented their findings in the April 8 issue of the journal Science. The astronomers studied a star known as V4334 Sgr, in the constellation Sagittarius. It is better known as "Sakurai's Object," after Japanese amateur astronomer Yukio Sakurai, who discovered it on February 20, 1996, when it suddenly burst into new brightness. At first, astronomers thought the outburst was a common nova explosion, but further study showed that Sakurai's Object was anything but common. The star is an old white dwarf that had run out of hydrogen fuel for nuclear fusion reactions in its core. Astronomers believe that some such stars can undergo a final burst of fusion in a shell of helium that surrounds a core of heavier nuclei such as carbon and oxygen. However, the

  1. World's fastest and most sensitive astronomical camera

    Science.gov (United States)

    2009-06-01

    The next generation of instruments for ground-based telescopes took a leap forward with the development of a new ultra-fast camera that can take 1500 finely exposed images per second even when observing extremely faint objects. The first 240x240 pixel images with the world's fastest high precision faint light camera were obtained through a collaborative effort between ESO and three French laboratories from the French Centre National de la Recherche Scientifique/Institut National des Sciences de l'Univers (CNRS/INSU). Cameras such as this are key components of the next generation of adaptive optics instruments of Europe's ground-based astronomy flagship facility, the ESO Very Large Telescope (VLT). ESO PR Photo 22a/09 The CCD220 detector ESO PR Photo 22b/09 The OCam camera ESO PR Video 22a/09 OCam images "The performance of this breakthrough camera is without an equivalent anywhere in the world. The camera will enable great leaps forward in many areas of the study of the Universe," says Norbert Hubin, head of the Adaptive Optics department at ESO. OCam will be part of the second-generation VLT instrument SPHERE. To be installed in 2011, SPHERE will take images of giant exoplanets orbiting nearby stars. A fast camera such as this is needed as an essential component for the modern adaptive optics instruments used on the largest ground-based telescopes. Telescopes on the ground suffer from the blurring effect induced by atmospheric turbulence. This turbulence causes the stars to twinkle in a way that delights poets, but frustrates astronomers, since it blurs the finest details of the images. Adaptive optics techniques overcome this major drawback, so that ground-based telescopes can produce images that are as sharp as if taken from space. Adaptive optics is based on real-time corrections computed from images obtained by a special camera working at very high speeds. Nowadays, this means many hundreds of times each second. The new generation instruments require these

  2. The Top Ten Astronomical 'breakthroughs' of the 20th century

    Directory of Open Access Journals (Sweden)

    Hughes, D. W.

    2007-10-01

    Full Text Available Astronomy was revolutionized in the 20th century. The electron was discovered in 1897 and this transformed spectroscopy and introduced plasma and magnetohydrodynamic physics and astro-chemistry. Einstein’s E = mc2, solved the problem of stellar energy generation and spawned the study of elemental nuclear synthesis. Large telescopes led to a boom in astronomical spectroscopic and photometric data collection, leading to such cornerstones as the Hertzprung-Russell diagram and the mass-luminosity relationship, and to the realization that the Universe contained a multitude of galaxies and was expanding. Radio astronomy was introduced and the advent of the space age saw the astronomical wavelength range expand into the ultraviolet, X-ray and gamma-ray regions, as well as the infrared and millimetre. We also startedwandering around roaming the Solar System instead of merely glimpsing its members from the bottom of our warm, turbulent atmosphere. Astronomical “breakthroughs” abounded. We have asked astronomers to select their “top ten” and these are listed and discussed in this paper.

  3. ISO Results Presented at International Astronomical Union

    Science.gov (United States)

    1997-08-01

    describes several stages in our cosmic ancestry, revealed when ISO examines their counterparts still observable today. The evolving galaxies In the beginning was hydrogen, mixed with helium and minute traces of other light atoms. These were the atomic products of the Big Bang, the hypothetical cataclysm that created the Universe more than 10 billion years ago. The primeval gas was very dull. Nature could not make dust from it, never mind a living creature. But gravity gathered the hydrogen and helium into stars, and by nuclear reactions the stars glowed. As the first stars aged, the reactions made novel chemical elements like carbon, oxygen and silicon. Expelled into the stars' surroundings, these materials reacted with one another and with hydrogen to make the icy, tarry and stony grains of cosmic dust. The vast assemblies of stars called galaxies became crucibles where Nature could use physics and chemistry to make new materials and new stars. Rays from the most distant galaxies have taken so many billions of years to reach us that we see them as they were when they were young. The farthest galaxy observed so far by ISO is a quasar called BR 1202-0225, dating from a time when the Universe was less than one-tenth of its present age. Already it is dusty. ISO has also observed many galaxies at about half the age of the Universe, by staring long and hard through a window in the dust of our own Milky Way Galaxy, called the Lockman Hole. In those that glow most brightly in the infrared, astronomers suspect that frantic star-making is in progress, in episodes called starbursts. In nearer galaxies, ISO's astronomers can relate strong infrared emissions to collisions and to violent eruptions in the galactic cores, which have punctuated the evolution of the galaxies. "Having ISO in space brings special opportunities for the study of the history of the galaxies," says the Japanese astronomer Yoshiaki Taniguchi of Tohoku University. "By detecting infrared wavelengths that are hard to

  4. Longwave Imaging for Astronomical Applications, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to develop a compact portable longwave camera for astronomical applications. In Phase 1, we successfully developed the eye of the camera, i.e. the focal...

  5. Astronomers no longer in the dark

    CERN Multimedia

    MacMillan, L

    2002-01-01

    In a significant breakthrough, British and US astronomers have begun to pin down the most elusive material in the universe. They have made a map of dark matter - the heavy, invisible stuff that gives the galaxies their shape (1 page).

  6. Astronomers find distant planet like Jupiter

    CERN Multimedia

    2003-01-01

    Astronomers searching for planetary systems like our solar system have found a planet similar to Jupiter orbiting a nearby star similar to our Sun, about 90 light-years from Earth, according to researchers (1/2 page).

  7. The Soviet center of astronomical data

    International Nuclear Information System (INIS)

    Dluzhnevskaya, O.B.

    1982-01-01

    On the basis of the current French-Soviet cooperation in science and technology, the Astronomical Council of the U.S.S.R. Academy of Sciences and the Strasbourg Center signed in 1977 an agreement on setting up the Soviet Center of Astronomical Data as its filial branch. The Soviet Center was created on the basis of a computation center at the Zvenigorod station of the Astronomical Council of the U.S.S.R. Academy of Sciences, which had already had considerable experience of working with stellar catalogues. In 1979 the Center was equipped with a EC-1033 computer. In 1978-1979 the Soviet Center of Astronomical Data (C.A.D.) received from Strasbourg 96 of the most important catalogues. By September 1981 the list of catalogues available at the Soviet Center has reached 140 catalogues some of which are described. (Auth.)

  8. Astronomers Discover Six-Image Gravitational Lens

    Science.gov (United States)

    2001-08-01

    An international team of astronomers has used the National Science Foundation's Very Long Baseline Array (VLBA) radio telescope and NASA's Hubble Space Telescope (HST) to discover the first gravitational lens in which the single image of a very distant galaxy has been split into six different images. The unique configuration is produced by the gravitational effect of three galaxies along the line of sight between the more-distant galaxy and Earth. Optical and Radio Images of Gravitational Lens "This is the first gravitational lens with more than four images of the background object that is produced by a small group of galaxies rather than a large cluster of galaxies," said David Rusin, who just received his Ph.D. from the University of Pennsylvania. "Such systems are expected to be extremely rare, so this discovery is an important stepping stone. Because this is an intermediate case between gravitational lenses produced by single galaxies and lenses produced by large clusters of galaxies, it will give us insights we can't get from other types of lenses," Rusin added. The gravitational lens, called CLASS B1359+154, consists of a galaxy more than 11 billion light-years away in the constellation Bootes, with a trio of galaxies more than 7 billion light-years away along the same line of sight. The more-distant galaxy shows signs that it contains a massive black hole at its core and also has regions in which new stars are forming. The gravitational effect of the intervening galaxies has caused the light and radio waves from the single, more-distant galaxy to be "bent" to form six images as seen from Earth. Four of these images appear outside the triangle formed by the three intermediate galaxies and two appear inside that triangle. "This lens system is a very interesting case to study because it is more complicated than lenses produced by single galaxies, and yet simpler than lenses produced by clusters of numerous galaxies," said Chris Kochanek of the Harvard

  9. "Movie Star" Acting Strangely, Radio Astronomers Find

    Science.gov (United States)

    1999-01-01

    Astronomers have used the National Science Foundation's Very Long Baseline Array (VLBA) radio telescope to make the first-ever time-lapse "movie" showing details of gas motions around a star other than our Sun. The study, the largest observational project yet undertaken using Very Long Baseline Interferometry, has produced surprising results that indicate scientists do not fully understand stellar atmospheres. The "movie" shows that the atmosphere of a pulsating star more than 1,000 light-years away continues to expand during a part of the star's pulsation period in which astronomers expected it to start contracting. Philip Diamond and Athol Kemball, of the National Radio Astronomy Observatory (NRAO) in Socorro, New Mexico, announced their findings at the American Astronomical Society's meeting in Austin, TX, today. "The continued expansion we're seeing contradicts current theoretical models for how these stars work," Diamond said. "The models have assumed spherical symmetry in the star's atmosphere, and our movie shows that this is not the case. Such models suggest that a shock wave passes outward from the star. Once it's passed, then the atmosphere should begin to contract because of the star's gravity. We've long passed that point and the contraction has not begun." The time-lapse images show that the gas motions are not uniform around the star. Most of the motion is that of gas moving directly outward from the star's surface. However, in about one-fourth of the ring, there are peculiar motions that do not fit this pattern. The scientists speculate that the rate of mass loss may not be the same from all parts of the star's surface. "A similar star behaved as predicted when studied a few years ago, so we're left to wonder what's different about this one," Diamond said. "Right now, we think that different rates of mass loss in the two stars may be the cause of the difference. This star is losing mass at 100 times the rate of the star in the earlier study." "This

  10. Database-Driven Analyses of Astronomical Spectra

    Science.gov (United States)

    Cami, Jan

    2012-03-01

    Spectroscopy is one of the most powerful tools to study the physical properties and chemical composition of very diverse astrophysical environments. In principle, each nuclide has a unique set of spectral features; thus, establishing the presence of a specific material at astronomical distances requires no more than finding a laboratory spectrum of the right material that perfectly matches the astronomical observations. Once the presence of a substance is established, a careful analysis of the observational characteristics (wavelengths or frequencies, intensities, and line profiles) allows one to determine many physical parameters of the environment in which the substance resides, such as temperature, density, velocity, and so on. Because of this great diagnostic potential, ground-based and space-borne astronomical observatories often include instruments to carry out spectroscopic analyses of various celestial objects and events. Of particular interest is molecular spectroscopy at infrared wavelengths. From the spectroscopic point of view, molecules differ from atoms in their ability to vibrate and rotate, and quantum physics inevitably causes those motions to be quantized. The energies required to excite vibrations or rotations are such that vibrational transitions generally occur at infrared wavelengths, whereas pure rotational transitions typically occur at sub-mm wavelengths. Molecular vibration and rotation are coupled though, and thus at infrared wavelengths, one commonly observes a multitude of ro-vibrational transitions (see Figure 13.1). At lower spectral resolution, all transitions blend into one broad ro-vibrational molecular band. The isotope. Molecular spectroscopy thus allows us to see a difference of one neutron in an atomic nucleus that is located at astronomical distances! Since the detection of the first interstellar molecules (the CH [21] and CN [14] radicals), more than 150 species have been detected in space, ranging in size from diatomic

  11. The Russian-Ukrainian Observatories Network for the European Astronomical Observatory Route Project

    Science.gov (United States)

    Andrievsky, S. M.; Bondar, N. I.; Karetnikov, V. G.; Kazantseva, L. V.; Nefedyev, Y. A.; Pinigin, G. I.; Pozhalova, Zh. A.; Rostopchina-Shakhovskay, A. N.; Stepanov, A. V.; Tolbin, S. V.

    2011-09-01

    In 2004,the Center of UNESCO World Heritage has announced a new initiative "Astronomy & World Heritage" directed for search and preserving of objects,referred to astronomy,its history in a global value,historical and cultural properties. There were defined a strategy of thematic programme "Initiative" and general criteria for selecting of ancient astronomical objects and observatories. In particular, properties that are situated or have significance in relation to celestial objects or astronomical events; representations of sky and/or celestial bodies and astronomical events; observatories and instruments; properties closely connected with the history of astronomy. In 2005-2006,in accordance with the program "Initiative", information about outstanding properties connected with astronomy have been collected.In Ukraine such work was organized by astronomical expert group in Nikolaev Astronomical Observatory. In 2007, Nikolaev observatory was included to the Tentative List of UNESCO under # 5116. Later, in 2008, the network of four astronomical observatories of Ukraine in Kiev,Crimea, Nikolaev and Odessa,considering their high authenticities and integrities,was included to the Tentative List of UNESCO under # 5267 "Astronomical Observatories of Ukraine". In 2008-2009, a new project "Thematic Study" was opened as a successor of "Initiative". It includes all fields of astronomical heritage from earlier prehistory to the Space astronomy (14 themes in total). We present the Ukraine-Russian Observatories network for the "European astronomical observatory Route project". From Russia two observatories are presented: Kazan Observatory and Pulkovo Observatory in the theme "Astronomy from the Renaissance to the mid-twentieth century".The description of astronomical observatories of Ukraine is given in accordance with the project "Thematic study"; the theme "Astronomy from the Renaissance to the mid-twentieth century" - astronomical observatories in Kiev,Nikolaev and Odessa; the

  12. Rosuvastatin ameliorates cognitive impairment in rats fed with high-salt and cholesterol diet via inhibiting acetylcholinesterase activity and amyloid beta peptide aggregation.

    Science.gov (United States)

    Husain, I; Akhtar, M; Abdin, M Zainul; Islamuddin, M; Shaharyar, M; Najmi, A K

    2018-04-01

    Amyloid beta (Aβ) peptide aggregation and cholinergic neurodegeneration are involved in the development of cognitive impairment. Therefore, in this article, we examined rosuvastatin (RSV), an oral hypolipidemic drug, to determine its potential as a dual inhibitor of acetylcholinesterase (AChE) and Aβ peptide aggregation for the treatment of cognitive impairment. Molecular docking study was done to examine the affinity of RSV with Aβ 1-42 and AChE in silico. We also employed neurobehavioral activity tests, biochemical estimation, and histopathology to study the anti-Aβ 1-42 aggregation capability of RSV in vivo. Molecular docking study provided evidence that RSV has the best binding conformer at its receptor site or active site of an enzyme. The cognitive impairment in female Wistar rats was induced by high-salt and cholesterol diet (HSCD) ad libitum for 8 weeks. RSV ameliorated serum cholesterol level, AChE activity, and Aβ 1-42 peptide aggregations in HSCD induced cognitive impairment. In addition, RSV-treated rats showed greater scores in the open field (locomotor activity) test. Moreover, the histopathological studies in the hippocampus and cortex of rat brain also supported that RSV markedly reduced the cognitive impairment and preserved the normal histoarchitectural pattern of the hippocampus and cortex. Taken together, these data indicate that RSV may act as a dual inhibitor of AChE and Aβ 1-42 peptide aggregation, therefore suggesting a therapeutic strategy for cognitive impairment treatment.

  13. Astronomers debate diamonds in space

    Science.gov (United States)

    1999-04-01

    This is not the first time the intriguing carbonaceous compound has been detected in space. A peculiar elite of twelve stars are known to produce it. The star now added by ISO to this elite is one of the best representatives of this exclusive family, since it emits a very strong signal of the compound. Additionally ISO found a second new member of the group with weaker emission, and also observed with a spectral resolution never achieved before other already known stars in this class. Astronomers think these ISO results will help solve the mystery of the true nature of the compound. Their publication by two different groups, from Spain and Canada, has triggered a debate on the topic, both in astronomy institutes and in chemistry laboratories. At present, mixed teams of astrophysicists and chemists are investigating in the lab compounds whose chemical signature or "fingerprint" matches that detected by ISO. Neither diamonds nor fullerenes have ever been detected in space, but their presence has been predicted. Tiny diamonds of pre-solar origin --older than the Solar System-- have been found in meteorites, which supports the as yet unconfirmed theory of their presence in interstellar space. The fullerene molecule, made of 60 carbon atoms linked to form a sphere (hence the name "buckyball"), has also been extensively searched for in space but never found. If the carbonaceous compound detected by ISO is a fullerene or a diamond, there will be new data on the production of these industrially interesting materials. Fullerenes are being investigated as "capsules" to deliver new pharmaceuticals to the body. Diamonds are commonly used in the electronics industry and for the development of new materials; if they are formed in the dust surrounding some stars, at relatively low temperatures and conditions of low pressure, companies could learn more about the ideal physical conditions to produce them. A textbook case The latest star in which the compound has been found is

  14. The effect of superdisintegrants on the properties and dissolution profiles of liquisolid tablets containing rosuvastatin.

    Science.gov (United States)

    Vraníková, Barbora; Gajdziok, Jan; Doležel, Petr

    2017-03-01

    The preparation of liquisolid systems (LSS) represents a promising method for enhancing a dissolution rate and bioavailability of poorly soluble drugs. The release of the drug from LSS tablets is affected by many factors, including the disintegration time. The evaluation of differences among LSS containing varying amounts and types of commercially used superdisintegrants (Kollidon® CL-F, Vivasol® and Explotab®). LSS were prepared by spraying rosuvastatin solution onto Neusilin® US2 and further processing into tablets. Varying amounts of superdisintegrants were used and the differences among LSS were evaluated. The multiple scatter plot method was used to visualize the relationships within the obtained data. All disintegrants do not showed negative effect on the flow properties of powder blends. The type and concentration of superdisintegrant had an impact on the disintegration time and dissolution profiles of tablets. Tablets with Explotab® showed the longest disintegration time and the smallest amount of released drug. Fastest disintegration and dissolution rate were observed in tablets containing Kollidon® CL-F (≥2.5% w/w). Also tablets with Vivasol® (2.5-4.0% w/w) showed fast disintegration and complete drug release. Kollidon® CL-F and Vivasol® in concentration ≥2.5% are suitable superdisintegrants for LSS with enhanced release of drug.

  15. Cost-effectiveness of rosuvastatin in comparison with generic atorvastatin and simvastatin in a Swedish population at high risk of cardiovascular events

    Directory of Open Access Journals (Sweden)

    Gandhi SK

    2012-01-01

    Full Text Available Sanjay K Gandhi1, Marie M Jensen2, Kathleen M Fox3, Lee Smolen4, Anders G Olsson5, Thomas Paulsson61AstraZeneca LP, Wilmington, DE, USA; 2AstraZeneca, Lund, Sweden; 3Strategic HealthCare Solution, Monkton, MD; 4Medical Decision Modeling Inc, Indianapolis, IN, USA; 5Department of Medical and Health Sciences, Linkoping University, and Stockholm Heart Center, Stockholm; 6AstraZeneca, Sodertalje, SwedenBackground: To assess the long-term cost-effectiveness of rosuvastatin therapy compared with generic simvastatin and generic atorvastatin in reducing the incidence of cardiovascular events and mortality in a Swedish population with Framingham risk ≥20%.Methods: A probabilistic Monte Carlo simulation model based on data from JUPITER (the Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin was used to estimate the long-term cost-effectiveness of rosuvastatin 20 mg daily versus simvastatin or atorvastatin 40 mg for the prevention of cardiovascular death and morbidity. The three-stage model included cardiovascular event prevention simulating the 4 years of JUPITER, initial prevention beyond the trial, and subsequent cardiovascular event prevention. A Swedish health care payer perspective (direct costs only was modeled for a lifetime horizon, with 2008/2009 as the costing period. Univariate and probabilistic sensitivity analyses were performed.Results: The incremental cost per quality-adjusted life-year (QALY gained with rosuvastatin 20 mg over simvastatin or atorvastatin 40 mg ranged from SEK88,113 (rosuvastatin 20 mg versus simvastatin 40 mg; Framingham risk ≥30%; net avoidance of 34 events/1000 patients to SEK497,542 (versus atorvastatin 40 mg: Framingham risk ≥20%; net avoidance of 11 events/1000 patients over a lifetime horizon. Probabilistic sensitivity analyses indicated that at a willingness-to-pay threshold of SEK500,000/QALY, rosuvastatin 20 mg would be cost-effective for approximately 75%–85

  16. Different Categories of Astronomical Heritage: Issues and Challenges

    Science.gov (United States)

    Ruggles, Clive

    2012-09-01

    Since 2008 the AWHWG has, on behalf of the IAU, been working with UNESCO and its advisory bodies to help identify, safeguard and promote cultural properties relating to astronomy and, where possible, to try to facilitate the eventual nomination of key astronomical heritage sites onto the World Heritage List. Unfortunately, the World Heritage Convention only covers fixed sites (i.e., the tangible immovable heritage of astronomy), and a key question for the UNESCO-IAU Astronomy and World Heritage Initiative (AWHI) is the extent to which the tangible moveable and intangible heritage of astronomy (e.g. moveable instruments; ideas and theories) influence the assessment of the tangible immovable heritage. Clearly, in an ideal world we should be concerned not only with tangible immovable heritage but, to quote the AWHWG's own Terms of Reference, ``to help ensure that cultural properties and artefacts significant in the development of astronomy, together with the intangible heritage of astronomy, are duly studied, protected and maintained, both for the greater benefit of humankind and to the potential benefit of future historical research''. With this in mind, the IAU/INAF symposium on ``Astronomy and its Instruments before and after Galileo'' held in Venice in Sep-Oct 2009 recommended that urgent steps should be taken 1. to sensitise astronomers and the general public, and particularly observatory directors and others with direct influence and control over astronomical resources, to the importance of identifying, protecting and preserving the various material products of astronomical research and discovery that already have, or have significant potential to acquire, universal value; (N.B. National or regional interests and concerns have no relevance in the assessment of ``universal value'', which, by definition, extends beyond cultural boundaries and, by reasonable expectation, down the generations into the future. 2. to identify modes of interconnectivity between

  17. Cholesterol Efflux Capacity, High-Density Lipoprotein Particle Number, and Incident Cardiovascular Events: An Analysis From the JUPITER Trial (Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin).

    Science.gov (United States)

    Khera, Amit V; Demler, Olga V; Adelman, Steven J; Collins, Heidi L; Glynn, Robert J; Ridker, Paul M; Rader, Daniel J; Mora, Samia

    2017-06-20

    Recent failures of drugs that raised high-density lipoprotein (HDL) cholesterol levels to reduce cardiovascular events in clinical trials have led to increased interest in alternative indices of HDL quality, such as cholesterol efflux capacity, and HDL quantity, such as HDL particle number. However, no studies have directly compared these metrics in a contemporary population that includes potent statin therapy and low low-density lipoprotein cholesterol. HDL cholesterol levels, apolipoprotein A-I, cholesterol efflux capacity, and HDL particle number were assessed at baseline and 12 months in a nested case-control study of the JUPITER trial (Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin), a randomized primary prevention trial that compared rosuvastatin treatment to placebo in individuals with normal low-density lipoprotein cholesterol but increased C-reactive protein levels. In total, 314 cases of incident cardiovascular disease (CVD) (myocardial infarction, unstable angina, arterial revascularization, stroke, or cardiovascular death) were compared to age- and gender-matched controls. Conditional logistic regression models adjusting for risk factors evaluated associations between HDL-related biomarkers and incident CVD. Cholesterol efflux capacity was moderately correlated with HDL cholesterol, apolipoprotein A-I, and HDL particle number (Spearman r = 0.39, 0.48, and 0.39 respectively; P capacity (OR/SD, 0.89; 95% CI, 0.72-1.10; P =0.28), HDL cholesterol (OR/SD, 0.82; 95% CI, 0.66-1.02; P =0.08), or apolipoprotein A-I (OR/SD, 0.83; 95% CI, 0.67-1.03; P =0.08). Twelve months of rosuvastatin (20 mg/day) did not change cholesterol efflux capacity (average percentage change -1.5%, 95% CI, -13.3 to +10.2; P =0.80), but increased HDL cholesterol (+7.7%), apolipoprotein A-I (+4.3%), and HDL particle number (+5.2%). On-statin cholesterol efflux capacity was inversely associated with incident CVD (OR/SD, 0.62; 95% CI, 0

  18. Muscular fixing of the H.M.D.P. {sup 99m}Tc induced by a statin, rosuvastatin or crestor: clinical case; Fixation musculaire du HMDP Tc99m induite par une statine, la rosuvastatine ou Crestor: cas clinique

    Energy Technology Data Exchange (ETDEWEB)

    Bourahla, K.; Hassler, S.; Schneegans, O.; Gyen, L.N. [CLCC Paul-Strauss, Service de medecine nucleaire, 67 - Strasbourg (France)

    2010-07-01

    Myositis induced by statins in treatment for hypercholesterolemia is a special clinical entity that may be encountered during an exploration by bone scintigraphy. We present the case of a muscle fixing observed in bone scan in a patient treated with rosuvastatin (Crestor). Muscular extra bone fixing of hydroxy-methane diphosphonate (H.M.D.P.) {sup 99m}T in patients referred for staging of prostate carcinoma, patients sometimes also treated for high cholesterol may be iatrogenic due to taking statins. A simple history may then allow its identification, although it remains asymptomatic. (N.C.)

  19. Association of Lipoproteins, Insulin Resistance, and Rosuvastatin With Incident Type 2 Diabetes Mellitus : Secondary Analysis of a Randomized Clinical Trial.

    Science.gov (United States)

    Dugani, Sagar B; Akinkuolie, Akintunde O; Paynter, Nina; Glynn, Robert J; Ridker, Paul M; Mora, Samia

    2016-05-01

    Statins decrease levels of low-density lipoprotein (LDL) and triglycerides as well as cardiovascular events but increase the risk for a diagnosis of type 2 diabetes mellitus (T2DM). The risk factors associated with incident T2DM are incompletely characterized. To investigate the association of lipoprotein subclasses and size and a novel lipoprotein insulin resistance (LPIR) score (a composite of 6 lipoprotein measures) with incident T2DM among individuals randomized to a high-intensity statin or placebo. This secondary analysis of the JUPITER trial (a placebo-controlled randomized clinical trial) was conducted at 1315 sites in 26 countries and enrolled 17 802 men 50 years or older and women 60 years or older with LDL cholesterol levels less than 130 mg/dL, high-sensitivity C-reactive protein levels of at least 2 mg/L, and triglyceride levels less than 500 mg/dL. Those with T2DM were excluded. A prespecified secondary aim was to assess the effect of rosuvastatin calcium on T2DM. Incident T2DM was monitored for a median of 2.0 years. Data were collected from February 4, 2003, to August 20, 2008, and analyzed (intention-to-treat) from December 1, 2013, to January 21, 2016. Rosuvastatin calcium, 20 mg/d, or placebo. Size and concentration of lipids, apolipoproteins, and lipoproteins at baseline (11 918 patients with evaluable plasma samples) and 12 months after randomization (9180 patients). The LPIR score, a correlate of insulin resistance, was calculated as a weighted combination of size and concentrations of LDL, very low-density lipoprotein (VLDL), and high-density lipoprotein (HDL) particles. Among the 11 918 patients (4334 women [36.4%]; median [interquartile range] age, 66 [60-71] years), rosuvastatin lowered the levels of LDL particles (-39.6%; 95% CI, -49.4% to -24.6%), VLDL particles (-19.6%; 95% CI, -40.6% to 10.3%), and VLDL triglycerides (-15.2%; 95% CI, -35.9% to 11.3%) and shifted the lipoprotein subclass distribution toward smaller LDL size (-1.5%; 95

  20. Maraghe Observatory and an Effort towards Retrieval of Architectural Design of Astronomical Units

    Directory of Open Access Journals (Sweden)

    Javad Shekari Niri

    2015-03-01

    Full Text Available Maraghe observatory was built by such engineers as Moayiededdin Orozi etc. under supervision of Khaje Nasireddin Tousi in 7th century AH. The most significant feature associated with Maraghe observatory is the fact that architecture is employed to achieve astronomical purposes in this site. The reason for preferring observatory by astronomers was the fact that these units are superior to wooden and metal instruments with respect to accuracy, no size limitations, etc. Architectural design and function of astronomical units of Maraghe observatory site after discovery of its foundation in the course of explorations before Islamic Revolution remained unclear until recent years. After conducting required studies and investigations, the author managed to find significant cues and after some precise comparisons, he succeeded to recover the main design and function of some astronomical units of this international center. Based on these findings these astronomical structures can reliably be rebuilt. This research showed that every circular or polygonal building cannot be considered as an observatory. For example form and function of cemetery structures are completely different with astronomical ones. Following this research also valuable results were obtained in relation to stone architectural structures present on Maraghe observatory hill. In addition, claims about invention of astronomical units of Maraghe observatory by non-Iranian scientists are rejected and rights of Iranian scientists are rationally defended in this regard.

  1. The National Astronomical Observatory of Japan and Post-war Japanese Optical Astronomy

    Science.gov (United States)

    Tajima, Toshiyuki

    This paper depicts some aspects of the formative process of the Japanese optical and infrared astronomical community in the post-war period, featuring the transition of the National Astronomical Observatory of Japan(NAOJ). We take up three cases of telescope construction, examining their background and their contribution to the Japanese astronomical community. Through these cases, the characteristics of traditions and cultures of optical and infrared astronomy in Japan are considered. Although the Tokyo Astronomical Observatory (TAO) of the University of Tokyo, the predecessor of NAOJ, was originally founded as an agency for practical astronomical observation such as time and almanac service, it has become an international centre for all types of astrophysical research. Research and development of telescopes and observational instruments have become an important part of the astronomers' practice. Now, however, a number of Japanese universities are planning to have their own large to middle-sized telescopes, and a new style of astronomical research is emerging involving astrophysical studies utilising data acquired from the Virtual Observatory, so there is a distinct possibility that the status of the NAOJ will change even further in the future.

  2. CoQ10 Augments Rosuvastatin Neuroprotective Effect in a Model of Global Ischemia via Inhibition of NF-κB/JNK3/Bax and Activation of Akt/FOXO3A/Bim Cues

    Directory of Open Access Journals (Sweden)

    Sarah A. Abd El-Aal

    2017-10-01

    Full Text Available Statins were reported to lower the Coenzyme Q10 (CoQ10 content upon their inhibition of HMG-CoA reductase enzyme and both are known to possess neuroprotective potentials; therefore, the aim is to assess the possible use of CoQ10 as an adds-on therapy to rosuvastatin to improve its effect using global I/R model. Rats were allocated into sham, I/R, rosuvastatin (10 mg/kg, CoQ10 (10 mg/kg and their combination. Drugs were administered orally for 7 days before I/R. Pretreatment with rosuvastatin and/or CoQ10 inhibited the hippocampal content of malondialdehyde, nitric oxide, and boosted glutathione and superoxide dismutase. They also opposed the upregulation of gp91phox, and p47phox subunits of NADPH oxidase. Meanwhile, both agents reduced content/expression of TNF-α, iNOS, NF-κBp65, ICAM-1, and MPO. Besides, all regimens abated cytochrome c, caspase-3 and Bax, but increased Bcl-2 in favor of cell survival. On the molecular level, they increased p-Akt and its downstream target p-FOXO3A, with the inhibition of the nuclear content of FOXO3A to downregulate the expression of Bim, a pro-apoptotic gene. Additionally, both treatments downregulate the JNK3/c-Jun signaling pathway. The effect of the combination regimen overrides that of either treatment alone. These effects were reflected on the alleviation of the hippocampal damage in CA1 region inflicted by I/R. Together, these findings accentuate the neuroprotective potentials of both treatments against global I/R by virtue of their rigorous multi-pronged actions, including suppression of hippocampal oxidative stress, inflammation, and apoptosis with the involvement of the Akt/FOXO3A/Bim and JNK3/c-Jun/Bax signaling pathways. The study also nominates CoQ10 as an adds-on therapy with statins.

  3. Thirteenth Joint European and National Astronomical Meeting

    CERN Document Server

    Iniesta, J C

    2006-01-01

    The book gathers the invited talks to the XIII JENAM conference, organized this time by the European Astronomical Society (EAS) and the Spanish Astronomical Society (SEA), and hosted by the Instituto de Astrofísica de Andalucía (CSIC). All branches of astrophysics are encompassed from the largest scales and cosmology to the solar system and the Sun, through the galaxies and the stars, including a section on astronomical instrumentation. Very relevant experts from all over the world speak in a single book about the most recent, exciting results from their fields in a way which is useful for both researchers in these fields and colleagues working in other disciplines. The book is accompanied by a CD-ROM including the remaining contributions of the meeting in PDF format, hence opening a wide panorama of what is going on in astrophysics nowadays.

  4. Decoding the mechanisms of Antikythera astronomical device

    CERN Document Server

    Lin, Jian-Liang

    2016-01-01

    This book presents a systematic design methodology for decoding the interior structure of the Antikythera mechanism, an astronomical device from ancient Greece. The historical background, surviving evidence and reconstructions of the mechanism are introduced, and the historical development of astronomical achievements and various astronomical instruments are investigated. Pursuing an approach based on the conceptual design of modern mechanisms and bearing in mind the standards of science and technology at the time, all feasible designs of the six lost/incomplete/unclear subsystems are synthesized as illustrated examples, and 48 feasible designs of the complete interior structure are presented. This approach provides not only a logical tool for applying modern mechanical engineering knowledge to the reconstruction of the Antikythera mechanism, but also an innovative research direction for identifying the original structures of the mechanism in the future. In short, the book offers valuable new insights for all...

  5. Astronomers Without Borders: A Global Astronomy Community

    Science.gov (United States)

    Simmons, M.

    2011-10-01

    Astronomers Without Borders (AWB) brings together astronomy enthusiasts of all types - amateur astronomers, educators, professionals and "armchair" astronomers for a variety of online and physicalworld programs. The AWB web site provides social networking and a base for online programs that engage people worldwide in astronomy activities that transcend geopolitical and cultural borders. There is universal interest in astronomy, which has been present in all cultures throughout recorded history. Astronomy is also among the most accessible of sciences with the natural laboratory of the sky being available to people worldwide. There are few other interests for which people widely separated geographically can engage in activities involving the same objects. AWB builds on those advantages to bring people together. AWB also provides a platform where projects can reach a global audience. AWB also provides unique opportunities for multidisciplinary collaboration in EPO programs. Several programs including The World at Night, Global Astronomy Month and others will be described along with lessons learned.

  6. Astronomical Content in Rongorongo Tablet Keiti

    DEFF Research Database (Denmark)

    Wieczorek, Rafal

    2011-01-01

    Th e fi eld of rongorongo research: the study of Easter Island’s native script is in a peculiar state at the moment. While relative progress has been made in structural and statistical analysis in the last decades, at the level of both single glyphs as well as entire texts, little to no advanceme...... has been achieved in the actual decipherment. To shed new light on rongorongo research, a hypothesis regarding the contents of tablet Keiti, one of the 25 obtained artifacts, is proposed. Th e content, as well as the meaning, of all but one of these 25 rongorongo texts is still unknown....... In this publication, an interpretation for the recto side of tablet Keiti is presented. It is argued that the tablet contains astronomical observations or instructions regarding the Rapa Nui lunar calendar, and is similar in content to the only other rongorongo text whose function has been partially ascertained......: tablet Mamari. If the calendrical contents of this artifact were confi rmed, this would be a major boost to our understanding of Oceania’s only native script....

  7. Conceptualizing Astronomical Distances for Urban Populations

    Science.gov (United States)

    Popinchalk, Mark; Olson, Kristen; Ingber, Jenny; O'Brien, Mariel

    2017-01-01

    Students living in urban environments may have a washed-out night sky, but their enthusiasm for astronomy can still shine bright. As an educator, it can sometimes be a challenge to see the opportunities afforded by city living to the teaching of astronomy; however, several benefits can be identified. For example, the intrinsic understanding children have of the distances and scales involved in their everyday life is enhanced when they live in a regimented urban structure. This existing understanding of scale is critical to building a foundation for later conceptualizing of the universe.Leveraging the assets of New York City and the resources found in the American Museum of Natural History, The Science and Nature Program offers students (PreK through 8th grade) robust science learning experiences. To address concepts important for studying astronomy, we present a novel twist on the classic lesson “Earth as a Peppercorn,” by scaling the solar system to the size of New York City. Using local landmarks and their distance in relation to the Museum to represent the planets, students can use their prior knowledge of their surroundings to appreciate the impressive scale of our neighborhood in space in the context of their own neighborhoods. We correlate the activity with NGSS standards, present preliminary feedback on it’s success, and discuss the opportunities to apply a similar model lesson to other astronomical systems.

  8. MYRaf: A new Approach with IRAF for Astronomical Photometric Reduction

    Science.gov (United States)

    Kilic, Y.; Shameoni Niaei, M.; Özeren, F. F.; Yesilyaprak, C.

    2016-12-01

    In this study, the design and some developments of MYRaf software for astronomical photometric reduction are presented. MYRaf software is an easy to use, reliable, and has a fast IRAF aperture photometry GUI tools. MYRaf software is an important step for the automated software process of robotic telescopes, and uses IRAF, PyRAF, matplotlib, ginga, alipy, and Sextractor with the general-purpose and high-level programming language Python and uses the QT framework.

  9. Coronagraph for astronomical imaging and spectrophotometry

    Science.gov (United States)

    Vilas, Faith; Smith, Bradford A.

    1987-01-01

    A coronagraph designed to minimize scattered light in astronomical observations caused by the structure of the primary mirror, secondary mirror, and secondary support structure of a Cassegrainian telescope is described. Direct (1:1) and reducing (2.7:1) imaging of astronomical fields are possible. High-quality images are produced. The coronagraph can be used with either a two-dimensional charge-coupled device or photographic film camera. The addition of transmission dispersing optics converts the coronagraph into a low-resolution spectrograph. The instrument is modular and portable for transport to different observatories.

  10. A Brief History of Manchester Astronomical Society

    Science.gov (United States)

    Kilburn, K. J.

    Manchester Astronomical Society celebrated its centenary in September 2003. But that centenary was of a hundred years as the MAS: the history of the society goes back much further, and can be traced directly to that great era of.public awareness of astronomy and amateur interest in Victorian England in the last half of the nineteenth century. Allan Chapman has discussed this period in detail, so the present paper concentrates on the MAS's particular influence on Manchester astronomers and recent work on the history of the society.

  11. Astronomers gossip about the (cosmic) neighborhood.

    Science.gov (United States)

    Jayawardhana, R

    1994-09-09

    The Hague, Netherlands, last month welcomed 2000 astronomers from around the world for the 22nd General Assembly of the International Astronomical Union (IAU). From 15 to 27 August, they participated in symposia and discussions on topics ranging from the down-to-Earth issue of light and radio-frequency pollution to the creation of elements at the farthest reaches of time and space, in the big bang. Some of the most striking news, however, came in new findings from our galaxy and its immediate surroundings.

  12. Novel Algorithms for Astronomical Plate Analyses

    Czech Academy of Sciences Publication Activity Database

    Hudec, René; Hudec, L.

    2011-01-01

    Roč. 32, 1-2 (2011), s. 121-123 ISSN 0250-6335. [Conference on Multiwavelength Variability of Blazars. Guangzhou, 22,09,2010-24,09,2010] R&D Projects: GA ČR GA205/08/1207 Grant - others:GA ČR(CZ) GA102/09/0997; MŠMT(CZ) ME09027 Institutional research plan: CEZ:AV0Z10030501 Keywords : astronomical plates * plate archives archives * astronomical algorithms Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 0.400, year: 2011

  13. Unveiling galaxies the role of images in astronomical discovery

    CERN Document Server

    Roy, Jean-René

    2017-01-01

    Galaxies are known as the building blocks of the universe, but arriving at this understanding has been a thousand-year odyssey. This journey is told through the lens of the evolving use of images as investigative tools. Initial chapters explore how early insights developed in line with new methods of scientific imaging, particularly photography. The volume then explores the impact of optical, radio and x-ray imaging techniques. The final part of the story discusses the importance of atlases of galaxies; how astronomers organised images in ways that educated, promoted ideas and pushed for new knowledge. Images that created confusion as well as advanced knowledge are included to demonstrate the challenges faced by astronomers and the long road to understanding galaxies. By examining developments in imaging, this text places the study of galaxies in its broader historical context, contributing to both astronomy and the history of science.

  14. Astronomers celebrate a year of new Hubble results

    Science.gov (United States)

    1995-02-01

    to reach the telescope, had indeed passed through helium, and not only that, the helium was of just the right variety to match the established theory. Dr Jakobsen has spent more than 20 years working on this subject. His recent efforts concentrated on seeking out a quasar unobscured by clouds of hydrogen, which block the tell-tale signature of helium. His search drew him to the Space Telescope project and during the telescope's early years in orbit he studied 25 likely quasars and found one promising candidate. Dr Jacobsen then had to wait for the telescope's new optics before he could get the quality of data he needed to prove the existence of helium. "We were looking for a break in the cloud cover, so to speak," the astronomer said. "We had a tantalising glimpse of the quasar with the aberrated telescope but it was only after we fixed it that we could really get a clear answer. One of the first things that we did once we had the corrective optics in place was look at this object and it was exactly as we'd hoped." Getting the Universe to measure up When it comes to studying the expansion of the Universe, however, the telescope has raised morn; questions than answers. By determining how fast the Universe is expanding astronomers will be able to calculate its age and size. It may then become possible to discover what is the ultimate fate of the Universe; will it simply continue to expand until it evaporates? Will the expansion come to a complete stop? Or will the Universe stop expanding, start contracting and end in a "big crunch"? The rate at which the Universe expands is known as the Hubble Constant or H0. To measure this value, astronomers need to calculate how far away a galaxy is and how fast it is moving away from us. The former is difficult to determine because reliable distance indicators, sometimes known as "cosmic yardsticks ", such as variable stars and supernovae, must be found in the galaxies. An international team of astronomers recently used the Hubble

  15. Effect of intensive lipid-lowering treatment compared to moderate lipid-lowering treatment with rosuvastatin on endothelial function in high risk patients

    DEFF Research Database (Denmark)

    Egede, Rasmus; Jensen, Lisette Okkels; Hansen, Henrik Steen

    2011-01-01

    on the endothelial function evaluated with endothelium-dependent and endothelium-independent flow-mediated dilatation (FMD). METHODS: 87 Statin-naive patients with ST-segment elevation myocardial infarction (STEMI) were randomized to 5mg or 40mg rosuvastatin. The FMD was assessed at baseline, 6months and after 12...

  16. Optimization of RPLC Conditions for Quantitative Analysis of Atorvastatin and Rosuvastatin in Pharmaceutical Dosage Form

    Directory of Open Access Journals (Sweden)

    Zehra ÜSTÜN

    2016-05-01

    Özet: Bu çalışmada, atorvastatin (ATV ve rosuvastatinin (RSV eş zamanlı tayini için ters faz sıvı kromatografi (RPLC metodu geliştirilmiş ve valide edilmiştir. Ayırmada X Terra C18 (250 mm x 4,6 mm, 5µm kolon kullanılmış ve 244 nm’ de yürütülen çalışmada akış hızı 1 mL dakika-1 olarak belirlenmiştir. Tanımlanan metodun doğrusal aralığı ATV için 3-13 µg mL-1, RSV için 4-14 µg mL-1olarak belirlenmiştir. Deneyde iç standart (IS olarak Losartan kullanılmıştır. ATV ve RSV için dedeksiyon limiti (LOD değerleri sırasıyla 0,133 ve 0,221 µg mL-1 olarak hesaplanmıştır. Kantitasyon limiti (LOQ değerleri ise ATV ve RSV için sırasıyla 0,473 ve 0,970 µg mL-1 olarak tayin edilmiştir. Elde edilen sonuçlara bakılarak, önerilen RPLC metodu ATV, RSV ve bunların farmasötik dozaj formlarının rutin analizlerinde kullanılabilir olduğu gözlemlenmiştir. Anahtar Kelimeler: Metot optimizasyonu, validasyon, eş zamanlı tayin, atorvastatin, rosuvastatin

  17. Astronomy Against Terrorism: an Educational Astronomical Observatory Project in Peru

    Science.gov (United States)

    Ishitsuka, M.; Montes, H.; Kuroda, T.; Morimoto, M.; Ishitsuka, J.

    2003-05-01

    The Cosmos Coronagraphic Observatory was completely destroyed by terrorists in 1988. In 1995, in coordination with the Minister of Education of Peru, a project to construct a new Educational Astronomical Observatory has been executed. The main purpose of the observatory is to promote an interest in basic space sciences in young students from school to university levels, through basic astronomical studies and observations. The planned observatory will be able to lodge 25 visitors; furthermore an auditorium, a library and a computer room will be constructed to improve the interest of people in astronomy. Two 15-cm refractor telescopes, equipped with a CCD camera and a photometer, will be available for observations. Also a 6-m dome will house a 60-cm class reflector telescope, which will be donated soon, thanks to a fund collected and organized by the Nishi-Harima Astronomical Observatory in Japan. In addition a new modern planetarium donated by the Government of Japan will be installed in Lima, the capital of Peru. These installations will be widely open to serve the requirements of people interested in science.

  18. Automatic astronomical coordinate determination using digital zenith cameras

    Directory of Open Access Journals (Sweden)

    S Farzaneh

    2009-12-01

    Full Text Available Celestial positioning has been used for navigation purposes for many years. Stars as the extra-terrestrial benchmarks provide unique opportunity in absolute point positioning. However, astronomical field data acquisition and data processing of the collected data is very time-consuming. The advent of the Global Positioning System (GPS nearly made the celestial positioning system obsolete. The new satellite-based positioning system has been very popular since it is very efficient and convenient for many daily life applications. Nevertheless, the celestial positioning method is never replaced by satellite-based positioning in absolute point positioning sense. The invention of electro-optical devices at the beginning of the 21st century was really a rebirth in geodetic astronomy. Today, the digital cameras with relatively high geometric and radiometric accuracy has opened a new insight in satellite attitude determination and the study of the Earth's surface geometry and physics of its interior, i.e., computation of astronomical coordinates and the vertical deflection components. This method or the so-called astrogeodetic vision-based method help us to determine astronomical coordinates with an accuracy better than 0.1 arc second. The theoretical background, an innovative transformation approach and the preliminary numerical results are addressed in this paper.

  19. Radio and Optical Telescopes for School Students and Professional Astronomers

    Science.gov (United States)

    Hosmer, Laura; Langston, G.; Heatherly, S.; Towner, A. P.; Ford, J.; Simon, R. S.; White, S.; O'Neil, K. L.; Haipslip, J.; Reichart, D.

    2013-01-01

    The NRAO 20m telescope is now on-line as a part of UNC's Skynet worldwide telescope network. The NRAO is completing integration of radio astronomy tools with the Skynet web interface. We present the web interface and astronomy projects that allow students and astronomers from all over the country to become Radio Astronomers. The 20 meter radio telescope at NRAO in Green Bank, WV is dedicated to public education and also is part of an experiment in public funding for astronomy. The telescope has a fantastic new web-based interface, with priority queuing, accommodating priority for paying customers and enabling free use of otherwise unused time. This revival included many software and hardware improvements including automatic calibration and improved time integration resulting in improved data processing, and a new ultra high resolution spectrometer. This new spectrometer is optimized for very narrow spectral lines, which will allow astronomers to study complex molecules and very cold regions of space in remarkable detail. In accordance with focusing on broader impacts, many public outreach and high school education activities have been completed with many confirmed future activities. The 20 meter is now a fully automated, powerful tool capable of professional grade results available to anyone in the world. Drop by our poster and try out real-time telescope control!

  20. Emerging technology for astronomical optics metrology

    Science.gov (United States)

    Trumper, Isaac; Jannuzi, Buell T.; Kim, Dae Wook

    2018-05-01

    Next generation astronomical optics will enable science discoveries across all fields and impact the way we perceive the Universe in which we live. To build these systems, optical metrology tools have been developed that push the boundary of what is possible. We present a summary of a few key metrology technologies that we believe are critical for the coming generation of optical surfaces.

  1. Cosmological field theory for observational astronomers

    International Nuclear Information System (INIS)

    Zel'Dovich, Y.B.

    1987-01-01

    Theories of the very early Universe that use scalar fields (i.e., the so-called inflationary models of the Universe) have now come into wide use. The inflationary universe approach may perhaps solve some of the most difficult enigmas about the Universe as a whole. The inflationary universe forms a good bridge between the quantum theory of the birth of the Universe (which is still in the initial stages of development) and the standard hot Big Bang theory (which is well established, at least qualitatively). Therefore, an understanding of the basic ideas of inflation is a must for astronomers interested in the broad picture of the science. Astronomers are mathematically oriented enough (via celestial mechanics, electromagnetic theory, magnetohydrodynamics, nuclear reactions,etc.) that there is no negative attitude towards formulae in general. What the astronomer lacks is a knowledge of recent developments in particle physics and field theory. The astronomer should not be blamed for this, because these branches of physics are developing in a very peculiar fashion: some subfields of it are progressing comparatively slowly, with experimental verifications at each and every step, while other subfields progress rapidly

  2. Astronomía en la cultura

    Science.gov (United States)

    López, A.; Giménez Benitez, S.; Fernández, L.

    La Astronomía en la Cultura es el estudio interdisciplinario a nivel global de la astronomía prehistórica, antigua y tradicional, en el marco de su contexto cultural. Esta disciplina abarca cualquier tipo de estudios o líneas de investigación en que se relacione a la astronomía con las ciencias humanas o sociales. En ella se incluyen tanto fuentes escritas, relatos orales como fuentes arqueológicas, abarcando entre otros, los siguientes temas: calendarios, observación práctica, cultos y mitos, representación simbólica de eventos, conceptos y objetos astronómicos, orientación astronómica de tumbas, templos, santuarios y centros urbanos, cosmología tradicional y la aplicación ceremonial de tradiciones astronómicas, la propia historia de la astronomía y la etnoastronomía (Krupp, 1989) (Iwaniszewski, 1994). En nuestro trabajo abordamos la historia y situación actual de esta disciplina, sus métodos y sus relaciones con otras áreas de investigación.

  3. Astronomers Detect Powerful Bursting Radio Source Discovery Points to New Class of Astronomical Objects

    Science.gov (United States)

    2005-03-01

    Astronomers at Sweet Briar College and the Naval Research Laboratory (NRL) have detected a powerful new bursting radio source whose unique properties suggest the discovery of a new class of astronomical objects. The researchers have monitored the center of the Milky Way Galaxy for several years and reveal their findings in the March 3, 2005 edition of the journal, “Nature”. This radio image of the central region of the Milky Way Galaxy holds a new radio source, GCRT J1745-3009. The arrow points to an expanding ring of debris expelled by a supernova. CREDIT: N.E. Kassim et al., Naval Research Laboratory, NRAO/AUI/NSF Principal investigator, Dr. Scott Hyman, professor of physics at Sweet Briar College, said the discovery came after analyzing some additional observations from 2002 provided by researchers at Northwestern University. “"We hit the jackpot!” Hyman said referring to the observations. “An image of the Galactic center, made by collecting radio waves of about 1-meter in wavelength, revealed multiple bursts from the source during a seven-hour period from Sept. 30 to Oct. 1, 2002 — five bursts in fact, and repeating at remarkably constant intervals.” Hyman, four Sweet Briar students, and his NRL collaborators, Drs. Namir Kassim and Joseph Lazio, happened upon transient emission from two radio sources while studying the Galactic center in 1998. This prompted the team to propose an ongoing monitoring program using the National Science Foundation’s Very Large Array (VLA) radio telescope in New Mexico. The National Radio Astronomy Observatory, which operates the VLA, approved the program. The data collected, laid the groundwork for the detection of the new radio source. “Amazingly, even though the sky is known to be full of transient objects emitting at X- and gamma-ray wavelengths,” NRL astronomer Dr. Joseph Lazio pointed out, “very little has been done to look for radio bursts, which are often easier for astronomical objects to produce

  4. Finding Hidden Treasures: Investigations in US Astronomical Plate Archives

    Czech Academy of Sciences Publication Activity Database

    Hudec, René; Hudec, L.

    2013-01-01

    Roč. 53, č. 1 (2013), s. 23-26 ISSN 1210-2709 R&D Projects: GA ČR GA205/08/1207 Institutional support: RVO:67985815 Keywords : astronomical data archives * astronomical photography * astronomical photographic archives Subject RIV: BH - Optics, Masers, Lasers

  5. TPCs in high-energy astronomical polarimetry

    International Nuclear Information System (INIS)

    Black, J K

    2007-01-01

    High-energy astrophysics has yet to exploit the unique and important information that polarimetry could provide, largely due to the limited sensitivity of previously available polarimeters. In recent years, numerous efforts have been initiated to develop instruments with the sensitivity required for astronomical polarimetry over the 100 eV to 10 GeV band. Time projection chambers (TPCs), with their high-resolution event imaging capability, are an integral part of some of these efforts. After a brief overview of current astronomical polarimeter development efforts, the role of TPCs will be described in more detail. These include TPCs as photoelectric X-ray polarimeters and TPCs as components of polarizationsensitive Compton and pair-production telescopes

  6. Astronomical Photometry Past, Present, and Future

    CERN Document Server

    Milone, Eugene F

    2011-01-01

    This book brings together experts in the field of astronomical photometry to discuss how their subfields provide the precision and accuracy in astronomical energy flux measurements that are needed to permit tests of astrophysical theories. Differential photometers and photometry, improvements in infrared precision, the improvements in precision and accuracy of CCD photometry, the absolute calibration of flux, the development of the Johnson UBVRI photometric system and other passband systems to measure and precisely classify specific types of stars and astrophysical quantities, and the current capabilities of spectrophotometry and polarimetry to provide precise and accurate data, are all discussed in this volume. The discussion of `differential’ or `two-star’ photometers ranges from early experiments in visual photometry through the Harvard and Princeton polarizing photometers to the pioneering work of Walraven and differential photometers designed to minimize effects of atmospheric extinction and to count...

  7. Division B Commission 6: Astronomical Telegrams

    Science.gov (United States)

    Yamaoka, H.; Green, D. W. E.; Samus, N. N.; Aksnes, K.; Gilmore, A. C.; Nakano, S.; Sphar, T.; Tichá, J.; Williams, G. V.

    2016-04-01

    IAU Commission 6 ``Astronomical Telegrams'' had a single business meeting during Honolulu General Assembly of the IAU. It took place on Tuesday, 11 August 2015. The meeting was attended by Hitoshi Yamaoka (President), Daniel Green (Director of the Central Bureau for Astronomical Telegrams, CBAT, via Skype), Steven Chesley (JPL), Paul Chodas (JPL), Alan Gilmore (Canterbury University), Shinjiro Kouzuma (Chukyo University), Paolo Mazzali (Co-Chair of the Supernova Working Group), Elena Pian (Scuola Normale Superiore di Pisa), Marion Schmitz (chair IAU Working Group Designations + NED), David Tholen (University of Hawaii), Jana Ticha (Klet Observatory), Milos Tichy (Klet Observatory), Giovanni Valsecchi (INAF\\slash Italy), Gareth Williams (Minor Planet Center). Apologies: Nikolai Samus (General Catalogue of Variable Stars, GCVS).

  8. Statistical methods for astronomical data analysis

    CERN Document Server

    Chattopadhyay, Asis Kumar

    2014-01-01

    This book introduces “Astrostatistics” as a subject in its own right with rewarding examples, including work by the authors with galaxy and Gamma Ray Burst data to engage the reader. This includes a comprehensive blending of Astrophysics and Statistics. The first chapter’s coverage of preliminary concepts and terminologies for astronomical phenomenon will appeal to both Statistics and Astrophysics readers as helpful context. Statistics concepts covered in the book provide a methodological framework. A unique feature is the inclusion of different possible sources of astronomical data, as well as software packages for converting the raw data into appropriate forms for data analysis. Readers can then use the appropriate statistical packages for their particular data analysis needs. The ideas of statistical inference discussed in the book help readers determine how to apply statistical tests. The authors cover different applications of statistical techniques already developed or specifically introduced for ...

  9. International Astronomical Union Sympoisum No.50

    CERN Document Server

    Westerlund, B

    1973-01-01

    Dr J. Landi Dessy, Director of the Astronomical Observatory, Cordoba, Argentina, invited the International Astronomical Union to hold a Symposium in Cordoba in connection with the celebration of the Centennial of the Cordoba Observatory; the date of foundation is October 24, 1871. He proposed that the Symposium should deal with Spectral Classification and Multicolour Photometry as seven years had elapsed since the Symposium No. 24 in Saltsj6baden, and much development had occurred in the field. The invitation and the proposal were accepted by the IAU, and the Symposium was held in Villa Carlos Paz, near Cordoba, between October 18 and October 24, 1971. It was attended by about 50 scientists representing Argentina, Canada, Chile, Den­ mark, France, Germany, Italy, Mexico, Sweden, Switzerland, U.K., U.S.A., Vatican City State and Venezuela. The Symposium was divided into four sessions: 1. Classification of slit spectra, 2. Classification of objective-prism spectra, 3. Photometric classification, 4. Catalogues ...

  10. Isaac Newton and the astronomical refraction.

    Science.gov (United States)

    Lehn, Waldemar H

    2008-12-01

    In a short interval toward the end of 1694, Isaac Newton developed two mathematical models for the theory of the astronomical refraction and calculated two refraction tables, but did not publish his theory. Much effort has been expended, starting with Biot in 1836, in the attempt to identify the methods and equations that Newton used. In contrast to previous work, a closed form solution is identified for the refraction integral that reproduces the table for his first model (in which density decays linearly with elevation). The parameters of his second model, which includes the exponential variation of pressure in an isothermal atmosphere, have also been identified by reproducing his results. The implication is clear that in each case Newton had derived exactly the correct equations for the astronomical refraction; furthermore, he was the first to do so.

  11. Recruitment and Retention of LGBTIQ Astronomers

    Science.gov (United States)

    Dixon, William Van Dyke

    2012-01-01

    While lesbian, gay, bisexual, transgender, intersex, or questioning (LGBTIQ) astronomers face many of the same workplace challenges as women and racial/ethnic minorities, from implicit bias to overt discrimination, other challenges are unique to this group. An obvious example is the absence at many institutions of health insurance and other benefits for the same-sex domestic partners of their employees. More subtle is the psychological toll paid by LGBTIQ astronomers who remain "in the closet," self-censoring every statement about their personal lives. Paradoxically, the culture of the physical sciences, in which sexuality, gender identity, and gender expression are considered irrelevant, can discourage their discussion, further isolating LGBTIQ researchers. Addressing these challenges is not just a matter of fairness; it is an essential tool in the recruitment and retention of the brightest researchers and in assuring their productivity. We will discuss these issues and what individuals and departments can to make their institutions more welcoming to their LGBTIQ colleagues.

  12. Astronomía Mocoví

    Science.gov (United States)

    López, A.; Giménez Benitez, S.; Fernández, L.

    El presente trabajo, es una revisión crítica de la astronomía en la cultura Mocoví, aportando a lo realizado previamente por Lehmann Nistche (Lehmann Nistche, 1924 y 1927) el resultado de nuestro trabajo de campo. Un mayor conocimiento de las cosmovisiones de las etnias de esta área es fundamental para una mejor comprensión de la dispersión de las ideas cosmológicas entre los pueblos aborígenes americanos, dada la importancia del corredor chaqueño como conexión entre las altas culturas andinas, la mesopotamia y la región pampeana (Susnik, 1972). Para ello se realiza una comparación con otras cosmovisiones del área americana. Nuestro aporte se enmarca dentro de las actuales líneas de trabajo mundialmente en desarrollo en Astronomía en la Cultura.

  13. The data analysis facilities that astronomers want

    International Nuclear Information System (INIS)

    Disney, M.

    1985-01-01

    This paper discusses the need and importance of data analysis facilities and what astronomers ideally want. A brief survey is presented of what is available now and some of the main deficiencies and problems with today's systems are discussed. The main sources of astronomical data are presented incuding: optical photographic, optical TV/CCD, VLA, optical spectros, imaging x-ray satellite, and satellite planetary camera. Landmark discoveries are listed in a table, some of which include: our galaxy as an island, distance to stars, H-R diagram (stellar structure), size of our galaxy, and missing mass in clusters. The main problems at present are discussed including lack of coordinated effort and central planning, differences in hardware, and measuring performance

  14. SPHEREx: Science Opportunities for the Astronomical Community

    Science.gov (United States)

    Cooray, Asantha; SPHEREx Science Team

    2018-01-01

    SPHEREx, a mission in NASA's Medium Explorer (MIDEX) program that was selected for Phase A study in August 2017, will perform an all-sky near-infrared spectral survey between 0.75 - 5.0 microns. The survey will reach 18.3 AB mag (5 sigma) in R=41 filters, with R=135 coverage between 4.2 - 5.0 microns. The key science topics of the SPHEREx team are: (a) primordial non-Gaussianity through 3-dimensional galaxy clustering; (b) extragalactic background light fluctuations; and (c) ices and biogenic molecules in the interstellar medium and towards protoplanetary environments.The large legacy dataset of SPHEREx will enable a large number of scientific studies and find interesting targets for follow-up observations with Hubble, JWST, ALMA, among other facilities. The SPHEREx catalog will include 1.4 billion galaxies, with redshifts secured for more than 10 and 120 million with fractional accuracies in error/(1+z) better than 0.3% and 3%, respectively. The spectral coverage and resolution provided by SPHEREx are adequate to determine redshifts for most WISE-detected sources with an accuracy better than 3%. The catalog will contain close to 1.5 million quasars including 300 bright QSOs at z > 7 during the epoch of reionization, based on observational extrapolations. The catalog will be adequate to obtain redshifts for all 25,000 galaxy clusters expected to be detected in X-rays with e-Rosita. SPHEREx produces all-sky maps of the Galactic emission lines, including hydrocarbon emission around 3 microns.In this poster, we will show example science studies the broader astronomical community will be able to lead using the SPHEREx database. We will also outline existing plans within the SPHEREx team to develop software tools to enable easy access to the data and to conduct catalog searches, and ways in which the community can provide input to the SPHEREx Science Team on scientific studies and data/software requirements for those studies. The team is eager to develop best software

  15. A website for astronomical news in Spanish

    Science.gov (United States)

    Ortiz-Gil, A.

    2008-06-01

    Noticias del Cosmos is a collection of web pages within the Astronomical Observatory of the University of Valencia's website where we publish short daily summaries of astronomical press releases. Most, if not all of, the releases are originally written in English, and often Spanish readers may find them difficult to understand because not many people are familiar with the scientific language employed in these releases. Noticias del Cosmos has two principal aims. First, we want to communicate the latest astronomical news on a daily basis to a wide Spanish-speaking public who would otherwise not be able to read them because of the language barrier. Second, daily news can be used as a tool to introduce the astronomical topics of the school curriculum in a more immediate and relevant way. Most of the students at school have not yet reached a good enough level in their knowledge of English to fully understand a press release, and Noticias del Cosmos offers them and their teachers this news in their mother tongue. During the regular programme of school visits at the Observatory we use the news as a means of showing that there is still a lot to be discovered. So far the visits to the website have been growing steadily. Between June 2003 and June 2007 we had more than 30,000 visits (excluding 2006). More than 50% of the visits come from Spain, followed by visitors from South and Central America. The feedback we have received from teachers so far has been very positive, showing the usefulness of news items in the classroom when teaching astronomy.

  16. Astronomical random numbers for quantum foundations experiments

    Science.gov (United States)

    Leung, Calvin; Brown, Amy; Nguyen, Hien; Friedman, Andrew S.; Kaiser, David I.; Gallicchio, Jason

    2018-04-01

    Photons from distant astronomical sources can be used as a classical source of randomness to improve fundamental tests of quantum nonlocality, wave-particle duality, and local realism through Bell's inequality and delayed-choice quantum eraser tests inspired by Wheeler's cosmic-scale Mach-Zehnder interferometer gedanken experiment. Such sources of random numbers may also be useful for information-theoretic applications such as key distribution for quantum cryptography. Building on the design of an astronomical random number generator developed for the recent cosmic Bell experiment [Handsteiner et al. Phys. Rev. Lett. 118, 060401 (2017), 10.1103/PhysRevLett.118.060401], in this paper we report on the design and characterization of a device that, with 20-nanosecond latency, outputs a bit based on whether the wavelength of an incoming photon is greater than or less than ≈700 nm. Using the one-meter telescope at the Jet Propulsion Laboratory Table Mountain Observatory, we generated random bits from astronomical photons in both color channels from 50 stars of varying color and magnitude, and from 12 quasars with redshifts up to z =3.9 . With stars, we achieved bit rates of ˜1 ×106Hz/m 2 , limited by saturation of our single-photon detectors, and with quasars of magnitudes between 12.9 and 16, we achieved rates between ˜102 and 2 ×103Hz /m2 . For bright quasars, the resulting bitstreams exhibit sufficiently low amounts of statistical predictability as quantified by the mutual information. In addition, a sufficiently high fraction of bits generated are of true astronomical origin in order to address both the locality and freedom-of-choice loopholes when used to set the measurement settings in a test of the Bell-CHSH inequality.

  17. Astronomy Legacy Project - Pisgah Astronomical Research Institute

    Science.gov (United States)

    Barker, Thurburn; Castelaz, Michael W.; Rottler, Lee; Cline, J. Donald

    2016-01-01

    Pisgah Astronomical Research Institute (PARI) is a not-for-profit public foundation in North Carolina dedicated to providing hands-on educational and research opportunities for a broad cross-section of users in science, technology, engineering and math (STEM) disciplines. In November 2007 a Workshop on a National Plan for Preserving Astronomical Photographic Data (2009ASPC,410,33O, Osborn, W. & Robbins, L) was held at PARI. The result was the establishment of the Astronomical Photographic Data Archive (APDA) at PARI. In late 2013 PARI began ALP (Astronomy Legacy Project). ALP's purpose is to digitize an extensive set of twentieth century photographic astronomical data housed in APDA. Because of the wide range of types of plates, plate dimensions and emulsions found among the 40+ collections, plate digitization will require a versatile set of scanners and digitizing instruments. Internet crowdfunding was used to assist in the purchase of additional digitization equipment that were described at AstroPlate2014 Plate Preservation Workshop (www.astroplate.cz) held in Prague, CZ, March, 2014. Equipment purchased included an Epson Expression 11000XL scanner and two Nikon D800E cameras. These digital instruments will compliment a STScI GAMMA scanner now located in APDA. GAMMA will be adapted to use an electroluminescence light source and a digital camera with a telecentric lens to achieve high-speed high-resolution scanning. The 1μm precision XY stage of GAMMA will allow very precise positioning of the plate stage. Multiple overlapping CCD images of small sections of each plate, tiles, will be combined using a photo-mosaic process similar to one used in Harvard's DASCH project. Implementation of a software pipeline for the creation of a SQL database containing plate images and metadata will be based upon APPLAUSE as described by Tuvikene at AstroPlate2014 (www.astroplate.cz/programs/).

  18. International astronomical remote present observation on IRC.

    Science.gov (United States)

    Ji, Kaifan; Cao, Wenda; Song, Qian

    On March 6 - 7, 1997, an international astronomical remote present observation (RPO) was made on Internet Relay Chat (IRC) for the first time. Seven groups in four countries, China, United States, Canada and Great Britain, used the 1 meter telescope of Yunnan observatory together by the way of remote present observation. Within minutes, images were "On-line" by FTP, and every one was able to get them by anonymous ftp and discuss them on IRC from different widely separated sites.

  19. AstroWeb -- Internet Resources for Astronomers

    Science.gov (United States)

    Jackson, R. E.; Adorf, H.-M.; Egret, D.; Heck, A.; Koekemoer, A.; Murtagh, F.; Wells, D. C.

    AstroWeb is a World Wide Web (WWW) interface to a collection of Internet accessible resources aimed at the astronomical community. The collection currently contains more than 1000 WWW, Gopher, Wide Area Information System (WAIS), Telnet, and Anonymous FTP resources, and it is still growing. AstroWeb provides the additional value-added services: categorization of each resource; descriptive paragraphs for some resources; searchable index of all resource information; 3 times daily search for ``dead'' or ``unreliable'' resources.

  20. The Astronomical Pulse of Global Extinction Events

    Directory of Open Access Journals (Sweden)

    David F.V. Lewis

    2006-01-01

    Full Text Available The linkage between astronomical cycles and the periodicity of mass extinctions is reviewed and discussed. In particular, the apparent 26 million year cycle of global extinctions may be related to the motion of the solar system around the galaxy, especially perpendicular to the galactic plane. The potential relevance of Milankovitch cycles is also explored in the light of current evidence for the possible causes of extinction events over a geological timescale.

  1. Preserving and Archiving Astronomical Photographic Plates

    Science.gov (United States)

    Castelaz, M. W.; Cline, J. D.

    2005-05-01

    Astronomical objects change with time. New observations complement past observations recorded on photographic plates. Analyses of changes provide essential routes to information about an object's formation, constitution and evolution. Preserving a century of photographic plate observations is thus of paramount importance. Plate collections are presently widely dispersed; plates may be stored in poor conditions, and are effectively inaccessible to both researchers and historians. We describe a planned project at Pisgah Astronomical Research Institute to preserve the collections of astronomical plates in the United States by gathering them into a single storage location. Collections will be sorted, cleaned, and cataloged on-line so as to provide access to researchers. Full scientific and historic use of the material then requires the observations themselves to be accessible digitally. The project's goal will be the availability of these data as a unique, fully-maintained scientific and educational resource. The new archive will support trans-disciplinary research such as the chemistry of the Earth's atmosphere, library information science, trends in local weather patterns, and impacts of urbanization on telescope use, while the hand-written observatory logs will be a valuable resource for science historians and biographers.

  2. Elizabeth Brown (1830-1899), solar astronomer

    Science.gov (United States)

    Creese, M.

    1998-08-01

    Were it not for the fact that she was a woman, Elizabeth Brown might well be thought of as a fairly typical nineteenth-century British amateur astronomer. She has a place, although a relatively modest one, in the distinguished group of people who, with their own fortunes, carried out much of the astronomical research being done in the country at a time before extensive government support was forthcoming for the work.1 Her career in fact follows a pattern common to several of the nineteenth-century men astronomers in that her full productive period came only after she was freed from her primary responsibilities; she did not have to amass the necessary financial resources as did many of the men,2 but she had the time-consuming responsibility, not unusual for a Victorian woman, of caring for a parent through a lengthy old age. Only after her father died at the age of ninety-one, did Elizabeth, then in her early fifties, begin her sixteen years of remarkable public activity in astronomy.

  3. AESoP: Astronomical Extinction Spectrophotometer

    Science.gov (United States)

    Linford, Justin; McGraw, J.; Zimmer, P.; Ackermann, M.; Fitch, J.

    2009-01-01

    The Earth's atmosphere is a major obstruction to the precision and accuracy of ground-based photometry. The atmosphere removes light from astronomical objects both by absorption and scattering by constituent molecules, aerosols and clouds. These effects can change significantly over short time periods and over modest angles on the sky. To further understand these effects, the UNM Measurement Astrophysics Group has designed, built and recently deployed the Astronomical Extinction Spectrophotometer (AESoP), a 100mm objective grating spectrometer. By monitoring bright stars in sensibly the same direction as a larger photometric telescope is observing, AESoP will measure the wavelength-dependent extinction due to the Earth's atmosphere from 450nm to 900nm on time scales of approximately one minute. The collocated Astronomical LIDAR for Extinction (ALE) provides a high-precision monochromatic extinction measurement at 527nm. Knowing the extinction at a single wavelength allows us to pin the relative spectra generated by AESoP. These extinction spectra can then be integrated over the bandpass of the photometric telescope system to create real time corrections of observations. We present the design and construction of AESoP along with the preliminary results of our first combined observing campaign. This effort is our first step toward breaking the 1% photometry barrier. This project is funded by AFRL Grant FA9451-04-2-0355

  4. GalileoMobile: Astronomical activities in schools

    Science.gov (United States)

    Dasi Espuig, Maria; Vasquez, Mayte; Kobel, Philippe

    GalileoMobile is an itinerant science education initiative run on a voluntary basis by an international team of astronomers, educators, and science communicators. Our team's main goal is to make astronomy accessible to schools and communities around the globe that have little or no access to outreach actions. We do this by performing teacher workshops, activities with students, and donating educational material. Since the creation of GalileoMobile in 2008, we have travelled to Chile, Bolivia, Peru, India, and Uganda, and worked with 56 schools in total. Our activities are centred on the GalileoMobile Handbook of Activities that comprises around 20 astronomical activities which we adapted from many different sources, and translated into 4 languages. The experience we gained in Chile, Bolivia, Peru, India, and Uganda taught us that (1) bringing experts from other countries was very stimulating for children as they are naturally curious about other cultures and encourages a collaboration beyond borders; (2) high-school students who were already interested in science were always very eager to interact with real astronomers doing research to ask for career advice; (3) inquiry-based methods are important to make the learning process more effective and we have therefore, re-adapted the activities in our Handbook according to these; (4) local teachers and university students involved in our activities have the potential to carry out follow-up activities, and examples are those from Uganda and India.

  5. Astrobiology: An astronomer's perspective

    International Nuclear Information System (INIS)

    Bergin, Edwin A.

    2014-01-01

    In this review we explore aspects of the field of astrobiology from an astronomical viewpoint. We therefore focus on the origin of life in the context of planetary formation, with additional emphasis on tracing the most abundant volatile elements, C, H, O, and N that are used by life on Earth. We first explore the history of life on our planet and outline the current state of our knowledge regarding the delivery of the C, H, O, N elements to the Earth. We then discuss how astronomers track the gaseous and solid molecular carriers of these volatiles throughout the process of star and planet formation. It is now clear that the early stages of star formation fosters the creation of water and simple organic molecules with enrichments of heavy isotopes. These molecules are found as ice coatings on the solid materials that represent microscopic beginnings of terrestrial worlds. Based on the meteoritic and cometary record, the process of planet formation, and the local environment, lead to additional increases in organic complexity. The astronomical connections towards this stage are only now being directly made. Although the exact details are uncertain, it is likely that the birth process of star and planets likely leads to terrestrial worlds being born with abundant water and organics on the surface

  6. Astronomical Virtual Observatories Through International Collaboration

    Directory of Open Access Journals (Sweden)

    Masatoshi Ohishi

    2010-03-01

    Full Text Available Astronomical Virtual Observatories (VOs are emerging research environment for astronomy, and 16 countries and a region have funded to develop their VOs based on international standard protocols for interoperability. The 16 funded VO projects have established the International Virtual Observatory Alliance (http://www.ivoa.net/ to develop the standard interoperable interfaces such as registry (meta data, data access, query languages, output format (VOTable, data model, application interface, and so on. The IVOA members have constructed each VO environment through the IVOA interfaces. National Astronomical Observatory of Japan (NAOJ started its VO project (Japanese Virtual Observatory - JVO in 2002, and developed its VO system. We have succeeded to interoperate the latest JVO system with other VOs in the USA and Europe since December 2004. Observed data by the Subaru telescope, satellite data taken by the JAXA/ISAS, etc. are connected to the JVO system. Successful interoperation of the JVO system with other VOs means that astronomers in the world will be able to utilize top-level data obtained by these telescopes from anywhere in the world at anytime. System design of the JVO system, experiences during our development including problems of current standard protocols defined in the IVOA, and proposals to resolve these problems in the near future are described.

  7. AWOB: A Collaborative Workbench for Astronomers

    Science.gov (United States)

    Kim, J. W.; Lemson, G.; Bulatovic, N.; Makarenko, V.; Vogler, A.; Voges, W.; Yao, Y.; Kiefl, R.; Koychev, S.

    2015-09-01

    We present the Astronomers Workbench (AWOB1), a web-based collaboration and publication platform for a scientific project of any size, developed in collaboration between the Max-Planck institutes of Astrophysics (MPA) and Extra-terrestrial Physics (MPE) and the Max-Planck Digital Library (MPDL). AWOB facilitates the collaboration between geographically distributed astronomers working on a common project throughout its whole scientific life cycle. AWOB does so by making it very easy for scientists to set up and manage a collaborative workspace for individual projects, where data can be uploaded and shared. It supports inviting project collaborators, provides wikis, automated mailing lists, calendars and event notification and has a built in chat facility. It allows the definition and tracking of tasks within projects and supports easy creation of e-publications for the dissemination of data and images and other resources that cannot be added to submitted papers. AWOB extends the project concept to larger scale consortia, within which it is possible to manage working groups and sub-projects. The existing AWOB instance has so far been limited to Max-Planck members and their collaborators, but will be opened to the whole astronomical community. AWOB is an open-source project and its source code is available upon request. We intend to extend AWOB's functionality also to other disciplines, and would greatly appreciate contributions from the community.

  8. Astrobiology: An astronomer's perspective

    Energy Technology Data Exchange (ETDEWEB)

    Bergin, Edwin A. [University of Michigan, Department of Astronomy, 500 Church Street, Ann Arbor, MI 48109 (United States)

    2014-12-08

    In this review we explore aspects of the field of astrobiology from an astronomical viewpoint. We therefore focus on the origin of life in the context of planetary formation, with additional emphasis on tracing the most abundant volatile elements, C, H, O, and N that are used by life on Earth. We first explore the history of life on our planet and outline the current state of our knowledge regarding the delivery of the C, H, O, N elements to the Earth. We then discuss how astronomers track the gaseous and solid molecular carriers of these volatiles throughout the process of star and planet formation. It is now clear that the early stages of star formation fosters the creation of water and simple organic molecules with enrichments of heavy isotopes. These molecules are found as ice coatings on the solid materials that represent microscopic beginnings of terrestrial worlds. Based on the meteoritic and cometary record, the process of planet formation, and the local environment, lead to additional increases in organic complexity. The astronomical connections towards this stage are only now being directly made. Although the exact details are uncertain, it is likely that the birth process of star and planets likely leads to terrestrial worlds being born with abundant water and organics on the surface.

  9. AAS Publishing News: Astronomical Software Citation Workshop

    Science.gov (United States)

    Kohler, Susanna

    2015-07-01

    Do you write code for your research? Use astronomical software? Do you wish there were a better way of citing, sharing, archiving, or discovering software for astronomy research? You're not alone! In April 2015, AAS's publishing team joined other leaders in the astronomical software community in a meeting funded by the Sloan Foundation, with the purpose of discussing these issues and potential solutions. In attendance were representatives from academic astronomy, publishing, libraries, for-profit software sharing platforms, telescope facilities, and grantmaking institutions. The goal of the group was to establish “protocols, policies, and platforms for astronomical software citation, sharing, and archiving,” in the hopes of encouraging a set of normalized standards across the field. The AAS is now collaborating with leaders at GitHub to write grant proposals for a project to develop strategies for software discoverability and citation, in astronomy and beyond. If this topic interests you, you can find more details in this document released by the group after the meeting: http://astronomy-software-index.github.io/2015-workshop/ The group hopes to move this project forward with input and support from the broader community. Please share the above document, discuss it on social media using the hashtag #astroware (so that your conversations can be found!), or send private comments to julie.steffen@aas.org.

  10. Combined ultraviolet studies of astronomical sources

    Science.gov (United States)

    Baliunas, S. L.; Dupree, A. K.; Elvis, M.; Huchra, J. P.; Kenyon, S.; Raymond, J. C.

    1986-01-01

    Topics addressed include: Cygnus Loop; P Cygni profiles in dwarf novae; YY Gem; nova shells; HZ Herculis; activity cycles in cluster giants; Alpha Ori; metal deficient giant stars; ultraviolet spectra of symbiotic stars detected by the Very Large Array; time variability in symbiotic stars; blue galaxies; and quasistellar objects with X-ray spectra.

  11. Amateur astronomers in support of observing campaigns

    Science.gov (United States)

    Yanamandra-Fisher, P.

    2014-07-01

    The Pro-Am Collaborative Astronomy (PACA) project evolved from the observational campaign of C/2012 S1 or C/ISON. The success of the paradigm shift in scientific research is now implemented in other comet observing campaigns. While PACA identifies a consistent collaborative approach to pro-am collaborations, given the volume of data generated for each campaign, new ways of rapid data analysis, mining access, and storage are needed. Several interesting results emerged from the synergistic inclusion of both social media and amateur astronomers: - the establishment of a network of astronomers and related professionals that can be galvanized into action on short notice to support observing campaigns; - assist in various science investigations pertinent to the campaign; - provide an alert-sounding mechanism should the need arise; - immediate outreach and dissemination of results via our media/blogger members; - provide a forum for discussions between the imagers and modelers to help strategize the observing campaign for maximum benefit. In 2014, two new comet observing campaigns involving pro-am collaborations have been identified: (1) C/2013 A1 (C/Siding Spring) and (2) 67P/Churyumov-Gerasimenko (CG). The evolving need for individual customized observing campaigns has been incorporated into the evolution of PACA (Pro-Am Collaborative Astronomy) portal that currently is focused on comets: from supporting observing campaigns for current comets, legacy data, historical comets; interconnected with social media and a set of shareable documents addressing observational strategies; consistent standards for data; data access, use, and storage, to align with the needs of professional observers. The integration of science, observations by professional and amateur astronomers, and various social media provides a dynamic and evolving collaborative partnership between professional and amateur astronomers. The recent observation of comet 67P, at a magnitude of 21.2, from Siding

  12. Astronomers Get New Tools for Gravitational-Wave Detection

    Science.gov (United States)

    2010-01-01

    Teamwork between gamma-ray and radio astronomers has produced a breakthrough in finding natural cosmic tools needed to make the first direct detections of the long-elusive gravitational waves predicted by Albert Einstein nearly a century ago. An orbiting gamma-ray telescope has pointed radio astronomers to specific locations in the sky where they can discover new millisecond pulsars. Millisecond pulsars, rapidly-spinning superdense neutron stars, can serve as extremely precise and stable natural clocks. Astronomers hope to detect gravitational waves by measuring tiny changes in the pulsars' rotation caused by the passage of the gravitational waves. To do this, they need a multitude of millisecond pulsars dispersed widely throughout the sky. However, nearly three decades after the discovery of the first millisecond pulsar, only about 150 of them had been found, some 90 of those clumped tightly in globular star clusters and thus unusable for detecting gravitational waves. The problem was that millisecond pulsars could only be discovered through arduous, computing-intensive searches of small portions of sky. "We've probably found far less than one percent of the millisecond pulsars in the Milky Way Galaxy," said Scott Ransom of the National Radio Astronomy Observatory (NRAO). The breakthrough came when an instrument aboard NASA's Fermi Gamma-Ray Space Telescope began surveying the sky in 2008. This instrument located hundreds of gamma-ray-emitting objects throughout our Galaxy, and astronomers suspected many of these could be millisecond pulsars. Paul Ray of the Naval Research Laboratory initiated an international collaboration to use radio telescopes to confirm the identity of these objects as millisecond pulsars. "The data from Fermi were like a buried-treasure map," Ransom said. "Using our radio telescopes to study the objects located by Fermi, we found 17 millisecond pulsars in three months. Large-scale searches had taken 10-15 years to find that many," Ransom

  13. Constructing Concept Schemes From Astronomical Telegrams Via Natural Language Clustering

    Science.gov (United States)

    Graham, Matthew; Zhang, M.; Djorgovski, S. G.; Donalek, C.; Drake, A. J.; Mahabal, A.

    2012-01-01

    The rapidly emerging field of time domain astronomy is one of the most exciting and vibrant new research frontiers, ranging in scientific scope from studies of the Solar System to extreme relativistic astrophysics and cosmology. It is being enabled by a new generation of large synoptic digital sky surveys - LSST, PanStarrs, CRTS - that cover large areas of sky repeatedly, looking for transient objects and phenomena. One of the biggest challenges facing these is the automated classification of transient events, a process that needs machine-processible astronomical knowledge. Semantic technologies enable the formal representation of concepts and relations within a particular domain. ATELs (http://www.astronomerstelegram.org) are a commonly-used means for reporting and commenting upon new astronomical observations of transient sources (supernovae, stellar outbursts, blazar flares, etc). However, they are loose and unstructured and employ scientific natural language for description: this makes automated processing of them - a necessity within the next decade with petascale data rates - a challenge. Nevertheless they represent a potentially rich corpus of information that could lead to new and valuable insights into transient phenomena. This project lies in the cutting-edge field of astrosemantics, a branch of astroinformatics, which applies semantic technologies to astronomy. The ATELs have been used to develop an appropriate concept scheme - a representation of the information they contain - for transient astronomy using hierarchical clustering of processed natural language. This allows us to automatically organize ATELs based on the vocabulary used. We conclude that we can use simple algorithms to process and extract meaning from astronomical textual data.

  14. Laboratory measurements and astronomical search for the HSO radical.

    Science.gov (United States)

    Cazzoli, Gabriele; Lattanzi, Valerio; Kirsch, Till; Gauss, Jürgen; Tercero, Belén; Cernicharo, José; Puzzarini, Cristina

    2016-07-01

    Despite the fact that many sulfur-bearing molecules, ranging from simple diatomic species up to astronomical complex molecules, have been detected in the interstellar medium, the sulfur chemistry in space is largely unknown and a depletion in the abundance of S-containing species has been observed in the cold, dense interstellar medium (ISM). The chemical form of the missing sulfur has yet to be identified. For these reasons, in view of the fact that there is a large abundance of triatomic species harbouring sulfur, oxygen, and hydrogen, we decided to investigate the HSO radical in the laboratory to try its astronomical detection. High-resolution measurements of the rotational spectrum of the HSO radical were carried out within a frequency range well up into the THz region. Subsequently, a rigorous search for HSO in the two most studied high-mass star-forming regions, Orion KL and Sagittarius (Sgr) B2, and in the cold dark cloud Barnard 1 (B1-b) was performed. The frequency coverage and the spectral resolution of our measurements allowed us to improve and extend the existing dataset of spectroscopic parameters, thus enabling accurate frequency predictions up to the THz range. These were used to derive the synthetic spectrum of HSO, by means of the MADEX code, according to the physical parameters of the astronomical source under consideration. For all sources investigated, the lack of HSO lines above the confusion limit of the data is evident. The derived upper limit to the abundance of HSO clearly indicates that this molecule does not achieve significant abundances in either the gas phase or in the ice mantles of dust grains.

  15. Effect of rosuvastatin on fasting and postprandial endothelial biomarker levels and microvascular reactivity in patients with type 2 diabetes and dyslipidemia: a preliminary report.

    Science.gov (United States)

    Kim, Kyoung Min; Jung, Kyong Yeun; Yun, Han Mi; Lee, Seo Young; Oh, Tae Jung; Jang, Hak Chul; Lim, Soo

    2017-11-09

    The cardiovascular benefits of statins have been proven, but their effect on circulation in small vessels has not been examined fully. We investigated the effect of 20 mg rosuvastatin on biomarkers, including paraoxonase-1 (PON-1) and asymmetric dimethylarginine (ADMA), and on microvascular reactivity. We enrolled 20 dyslipidemic patients with type 2 diabetes and 20 age- and body mass index (BMI)-matched healthy controls. Rosuvastatin (20 mg/day) was given to the patient group for 12 weeks. Biochemical parameters, including PON-1 and ADMA, were compared between the patient and control groups, and before and after rosuvastatin treatment in the patient group. Fasting and 2 h postprandial levels of PON-1 and ADMA after mixed-meal challenge were also compared. Microvascular reactivity in a peripheral artery was examined using laser Doppler flowmetry. The respective mean ± standard deviation of age and BMI were 50.1 ± 3.8 year and 25.8 ± 3.7 kg/m 2 in the patients and 50.2 ± 3.2 year and 25.4 ± 3.4 kg/m 2 in the controls. The patient group had worse profiles of cardiometabolic biomarkers, including PON-1 and ADMA, than the controls. In the patients treated with 20 mg rosuvastatin, low-density lipoprotein (LDL)-cholesterol decreased from 147.2 ± 26.5 to 68.3 ± 24.5 mg/dL and high-density lipoprotein (HDL)-cholesterol increased from 42.4 ± 5.2 to 44.7 ± 6.2 mg/dL (both P fasting and 2 h postprandial levels of PON-1 increased and those of ADMA decreased after treatment with rosuvastatin for 12 weeks. The changes in postprandial levels of both biomarkers were greater than those after fasting. Microcirculation assessed as reactive hyperemia in the patients after an ischemic challenge increased significantly from 335.3 ± 123.4 to 402.7 ± 133.4% after rosuvastatin treatment. The postprandial changes in the biomarkers were significantly associated with improvement of microvascular reactivity. Rosuvastatin treatment for 12

  16. Algorithms for classification of astronomical object spectra

    Science.gov (United States)

    Wasiewicz, P.; Szuppe, J.; Hryniewicz, K.

    2015-09-01

    Obtaining interesting celestial objects from tens of thousands or even millions of recorded optical-ultraviolet spectra depends not only on the data quality but also on the accuracy of spectra decomposition. Additionally rapidly growing data volumes demands higher computing power and/or more efficient algorithms implementations. In this paper we speed up the process of substracting iron transitions and fitting Gaussian functions to emission peaks utilising C++ and OpenCL methods together with the NOSQL database. In this paper we implemented typical astronomical methods of detecting peaks in comparison to our previous hybrid methods implemented with CUDA.

  17. Penn State astronomical image processing system

    International Nuclear Information System (INIS)

    Truax, R.J.; Nousek, J.A.; Feigelson, E.D.; Lonsdale, C.J.

    1987-01-01

    The needs of modern astronomy for image processing set demanding standards in simultaneously requiring fast computation speed, high-quality graphic display, large data storage, and interactive response. An innovative image processing system was designed, integrated, and used; it is based on a supermicro architecture which is tailored specifically for astronomy, which provides a highly cost-effective alternative to the traditional minicomputer installation. The paper describes the design rationale, equipment selection, and software developed to allow other astronomers with similar needs to benefit from the present experience. 9 references

  18. Le Verrier magnificent and detestable astronomer

    CERN Document Server

    Lequeux, James

    2013-01-01

    Le Verrier was a superb scientist. His discovery of Neptune in 1846 made him the most famous astronomer of his time. He produced a complete theory of the motions of the planets which served as a basis for planetary ephemeris for a full century. Doing this, he discovered an anomaly in the motion of Mercury which later became the first proof of General Relativity. He also founded European meteorology. However his arrogance and bad temper created many enemies, and he was even fired from his position of Director of the Paris Observatory.

  19. The astronomical revolution Copernicus, Kepler, Borelli

    CERN Document Server

    Koyre, Alexandre

    2013-01-01

    Originally published in English in 1973. This volume traces the development of the revolution which so drastically altered man's view of the universe in the sixteenth and seventeenth centuries. The ""astronomical revolution"" was accomplished in three stages, each linked with the work of one man. With Copernicus, the sun became the centre of the universe. With Kepler, celestial dynamics replaced the kinematics of circles and spheres used by Copernicus. With Borelli the unification of celestial and terrestrial physics was completed by abandonment of the circle in favour the straight line to inf

  20. Care of astronomical telescopes and accessories a manual for the astronomical observer and amateur telescope maker

    CERN Document Server

    Pepin, M Barlow

    2005-01-01

    Commercially-made astronomical telescopes are better and less expensive than ever before, and their optical and mechanical performance can be superb. When a good-quality telescope fails to perform as well as it might, the reason is quite probably that it needs a little care and attention! Here is a complete guide for anyone who wants to understand more than just the basics of astronomical telescopes and accessories, and how to maintain them in the peak of condition. The latest on safely adjusting, cleaning, and maintaining your equipment is combined with thoroughly updated methods from the old masters. Here, too, are details of choosing new and used optics and accessories, along with enhancements you can make to extend their versatility and useful lifetime. This book is for you. Really. Looking after an astronomical telescope isn't only for the experts - although there are some things that only an expert should attempt - and every serious amateur astronomer will find invaluable information here, gleaned from ...

  1. 150th Anniversary of the Astronomical Observatory Library of Sciences

    Science.gov (United States)

    Solntseva, T.

    The scientific library of the Astronomical observatory of Kyiv Taras Shevchenko University is one of the oldest ones of such a type in Ukraine. Our Astronomical Observatory and its scientific library will celebrate 150th anniversary of their foundation. 900 volumes of duplicates of Olbers' private library underlay our library. These ones were acquired by Russian Academy of Sciences for Poulkovo observatory in 1841 but according to Struve's order were transmitted to Kyiv Saint Volodymyr University. These books are of great value. There are works edited during Copernicus', Kepler's, Galilei's, Newton's, Descartes' lifetime. Our library contains more than 100000 units of storage - monographs, periodical astronomical editions from the first (Astronomische Nachrichten, Astronomical journal, Monthly Notices etc.), editions of the majority of the astronomical observatories and institutions of the world, unique astronomical atlases and maps

  2. Harvey Butcher: a passion for astronomical instrumentation

    Science.gov (United States)

    Bhathal, Ragbir

    2014-11-01

    This paper covers some aspects of the scientific life of Harvey Butcher who was the Director of the Research School for Astronomy and Astrophysics at the Australian National University in Canberra from September 2007 to January 2013. He has made significant contributions to research on the evolution of galaxies, nucleosynthesis, and on the design and implementation of advanced astronomical instrumentation including LOFAR (Low Frequency Array Radio telescope). He is well known for his discovery of the Butcher-Oemler effect. Before coming to Australia he was the Director of the Netherlands Foundation for Research in Astronomy from September 1991 to January 2007. In 2005 he was awarded a Knighthood in the Order of the Netherlands Lion for contributions to interdisciplinary science, innovation and public outreach.This paper is based on an interview conducted by the author with Harvey Butcher for the National Project on Significant Australian Astronomers sponsored by the National Library of Australia. Except otherwise stated, all quotations used in this paper are from the Butcher interview which has been deposited in the Oral History Archives of the National Library.

  3. "She is an astronomer" in Spain; the International Year of Astronomy 2009 and beyond

    Science.gov (United States)

    Márquez, I.

    2011-11-01

    The work of the Spanish node for the IYA2009 Cornerstoneproject, "She is an Astronomer" is presented. Our team developedseveral projects with the common goal of promoting gender equality andwomen participation in professional and amateur astronomy, andsupporting the training of young women researchers andtechnologists. The main ones were: 1)Calendar "Women astronomerswho made history". We highlighted exceptional women, fromdifferent epochs and countries, whose contributions to theadvancement of science deserve to transcend anonymity and occupy aplace in history.2) "Women in the stars" was a series of 8 TV programsdevoted to the contribution of Spanish women astronomers, made incollaboration with the UNED.3) "Women in Spanish Astronomy: analysis of a peculiar situation: A universe to discover", was the first sociological study of this type, including quantitative and qualitative (individual and group interviews) analyses. 4) The exhibit "She Astronomer", was aimed at teaching astronomy from a new perspective: the relevant contributions by women astronomers from different times and places.The main aims of the "Commission for Women and Astronomy",recently created within the Spanish Astronomical Society (SEA), are alsodescribed.

  4. Young Astronomers' Observe with ESO Telescopes

    Science.gov (United States)

    1995-11-01

    Today, forty 16-18 year old students and their teachers are concluding a one-week, educational `working visit' to the ESO Headquarters in Garching (See ESO Press Release 14/95 of 8 November 1995). They are the winners of the Europe-wide contest `Europe Towards the Stars', organised by ESO with the support of the European Union, under the auspices of the Third European Week for Scientific and Technological Culture. From November 14-20, they have worked with professional ESO astronomers in order to get insight into the methods and principles of modern astronomy and astrophysics, as carried out at one of the world's foremost international centres. This included very successful remote observations with the ESO 3.5-m New Technology Telescope (NTT) and the 1.4-m Coude Auxiliary Telescope (CAT) via a satellite link between the ESO Headquarters and the La Silla observatory in Chile, 12,000 kilometres away. After a general introduction to modern astronomy on the first day of the visit, the participants divided into six teams, according to their interests. Some chose to observe distant galaxies, others prefered to have a closer look on binary stars, and one team decided to investigate a star which is thought to be surrounded by a proto-planetary system. Each team was supported by an experienced ESO astronomer. Then followed the observations at the remote consoles during three nights, the first at the NTT and the following at the CAT. Each team had access to the telescope during half a night. Although the work schedule - exactly as in `real' science - was quite hard, especially during the following data reduction and interpretative phase, all teams managed extremely well and in high spirits. The young astronomers' observations were favoured by excellent atmospheric conditions. At the NTT, the seeing was better than 0.5 arcsecond during several hours, an exceptional value that allows very good images to be obtained. All observations represent solid and interesting science, and

  5. New astronomical references in two Catalonian late medieval documents.

    Science.gov (United States)

    Martínez, María José; Marco, Francisco J

    2014-01-01

    In 2008, after 13 years of preparation, the Generalitat of Catalunya finished the publication of the 10 volumes of the Dietaris de la Generalitat de Catalunya. The Dietaris, as well as a closely related source, the llibre de Jornades 1411/1484 de Jaume Safont, cover the period of 1411 to 1539. In this article, we examine astronomical references contained in these two sources, and place them in their historical context. Our main focus lies on astronomical phenomena that have not previously been published in the astronomical literature. In fact, relatively few astronomical records are accessible in Spanish medieval and early modern history, and our paper intends to fill this gap partially.

  6. The First Astronomical Observatory in Cluj-Napoca

    Science.gov (United States)

    Szenkovits, Ferenc

    2008-09-01

    One of the most important cities of Romania is Cluj-Napoca (Kolozsvár, Klausenburg). This is a traditional center of education, with many universities and high schools. From the second half of the 18th century the University of Cluj has its own Astronomical Observatory, serving for didactical activities and scientific researches. The famous astronomer Maximillian Hell was one of those Jesuits who put the base of this Astronomical Observatory. Our purpose is to offer a short history of the beginnings of this Astronomical Observatory.

  7. Astronomers, Transits of Venus, and the Birth of Experimental Psychology

    Science.gov (United States)

    Sheehan, William; Thurber, S.

    2012-01-01

    The eighteenth century transits of Venus were regarded as the most important astronomical events of their era. Halley's expectation was that by observing the contact points between the limbs of Venus and the Sun, this distance could be determined to an accuracy of one part in 500. But in the event, it proved otherwise. But, as the British historian Agnes Clerke wrote in 1902: "A transit of Venus seems, at first sight, full of promise for solving the problem of the sun's distance. For nothing would appear easier than to determine exactly either the duration of the passage of a small, dark orb across a large brilliant disc, or the instant of its entry upon or exit from it". But in that word `exactly' what snares and pitfalls lie hid!” In the post-mortem analysis of the disappointing results, astronomers devoted a great deal of effort to understand the sources of errors. They rehearsed their observational techniques by observing, under strictly controlled conditions, transits of artificial planets across artificial Suns, and studied such parameters as attention and reflex reaction. In the process, the transits of Venus provided an important impetus to the early development of experimental psychology.

  8. Astronomical Heritage and Aboriginal People: Conflicts and Possibilities

    Science.gov (United States)

    López, Alejandro Martín

    2016-10-01

    In this presentation we address issues relating to the astronomical heritage of contemporary aboriginal groups and other minorities. We deal specially with intangible astronomical heritage and its particularities. Also, we study (from ethnographic experience with Aboriginal groups, Creoles and Europeans in the Argentine Chaco) the conflicts referring to the different ways in which the natives' knowledge and practice are categorized by the natives themselves, by scientists, state politicians, professional artists and NGOs. Furthermore, we address several cases that illustrate these kinds of conflicts. We aim to analyze the complexities of patrimonial policies when they are applied to practices and representations of contemporary communities involved in power relations with national states and the global system. The essentialization of identities, the folklorization of representations and practices, and the fossilization of aboriginal peoples are some of the risks of applying the label ``cultural heritage'' without a careful consideration of each specific case. In particular we suggest possible ways in which the international scientific community could collaborate to improve the agenda of national states instead of reproducing colonial prejudices. In this way, we aim to contribute to the promotion of respect for ethnic and religious minorities.

  9. Thirty years of astronomical discovery with UKIRT

    CERN Document Server

    Davies, John; Robson, Ian; The Scientific Achievement of the United Kingdom InfraRed Telescope

    2013-01-01

    These are the proceedings of an international meeting hosted by the Royal Observatory, Edinburgh, to commemorate the 30th anniversary of the dedication of the UKIRT, the United Kingdom InfraRed Telescope. The volume comprises 31 professional level papers. The first part of the book has 10 thorough reviews of the conception, design and build of the telescope, as well as accounts of some its key instruments such as IRCAM (the common-user infrared camera), CGS4 (the fourth Cooled Grating Spectrometer) and the Wide Field Camera. The second part of the book comprises 14 reviews of scientific achievements during its twenty years of visitor mode operations. The final part of the book is a series of 7 reviews of the results from the multiple surveys being done as part of UKIDSS (UKIRT Infrared Deep Sky Survey). The authors are all experts in their respective fields, for example instrument scientists, operations staff and leading astronomers.

  10. Simon Newcomb: America's Unofficial Astronomer Royal

    Science.gov (United States)

    Graham, John

    2007-10-01

    Bill Carter and Merri Sue Carter Mantazas; xiii + 213 pp.; ISBN 1-59113-803-5 2006; $26.95 This book introduced me to a commanding figure in American science from the late nineteenth century: Simon Newcomb. Newcomb has been called the nineteenth-century equivalent of Carl Sagan and Albert Einstein. He rose from humble beginnings to be the preeminent American astronomer of his generation. He made basic, far-reaching, and enduring contributions to positional astronomy and planetary dynamics. On the more practical side, he determined a remarkably accurate value for the velocity of light, one within 0.01% of the value accepted today. His work provided an experimental grounding for the special and general theories of relativity to be formulated by Einstein in the coming twentieth century.

  11. Multinational History of Strasbourg Astronomical Observatory

    CERN Document Server

    Heck, André

    2005-01-01

    Strasbourg Astronomical Observatory is quite an interesting place for historians: several changes of nationality between France and Germany, high-profile scientists having been based there, big projects born or installed in its walls, and so on. Most of the documents circulating on the history of the Observatory and on related matters have however been so far poorly referenced, if at all. This made necessary the compilation of a volume such as this one, offering fully-documented historical facts and references on the first decades of the Observatory history, authored by both French and German specialists. The experts contributing to this book have done their best to write in a way understandable to readers not necessarily hyperspecialized in astronomy nor in the details of European history. After an introductory chapter by the Editor, contributions by Wolfschmidt and by Duerbeck respectively deal extensively with the German periods and review people and instrumentation, while another paper by Duerbeck is more...

  12. Shirakatsi Astronomical and Natural Philosophical Views

    Science.gov (United States)

    Mkrtchyan, Lilit

    2016-12-01

    Our work is aimed at presenting Shirakatsi astronomical and natural philosophical views. Karl Anania Shirakatsi is classified as one of the world-class intellectual geniuses. He was endowed with exceptional talent and analyzing scientific understanding of natural phenomena. He refers his philosophical works to almost all fields of science, cosmography, mathematics, calendarology, historiography, etc. Shirakatsy's earnings of natural science and natural philosophy in medieval is too big He was the first prominent scholar and thinker of his time, creating a unique, comprehensive gitapilisopayakan system that still feeds the human mind. The scientific value of Shirakatsi has great importance not only for Armenians but also for the whole world of science, history, culture and philosophy. Shirakatsi can be considered not only national but also universal greatness.

  13. From Casual Stargazer to Amateur Astronomer

    Science.gov (United States)

    Eagle, Dave

    The word amateur stems from the French word Amour, meaning "Lover Of". And there is a whole army of amateur astronomers around the world who just love doing astronomy. They don't get paid for the privilege of experiencing the sky in all its glory, but by making detailed observations they do make a very important contribution towards the Science. These observations are especially useful when organized as a collective effort. Citizen science has really taken off in the last few years and the GAIA project will soon be producing so much data, that the professionals just will not have enough manpower to tackle all the data. They will rely on amateurs sitting on their computers at home. But it is under a dark sky that astronomy really comes alive. The fact that you have picked up this book, must mean that you are interested in taking the hobby a step forward.

  14. Fundamental and applied aspects of astronomical seeing

    International Nuclear Information System (INIS)

    Coulman, C.E.

    1985-01-01

    It is pointed out that despite recent advances in the use of spacecraft as observatory platforms, much astronomy is still conducted from the surface of the earth. The literature on astronomical seeing and observatory site selection is widely scattered throughout journals and conference reports concerned with various disciplines. This survey has the objective to represent the state of the subject up to 1982. A description of the history and prospects of the considered subject is presented, and the optics of seeing are examined. The meteorology of seeing is discussed, taking into account aspects of micrometeorology and small-scale turbulence near the surface, the diurnal cycle in the planetary boundary layer, the temperature structure above the planetary boundary layer, and the effects of terrain. Attention is given to the calculation of system performance from microthermal data, optical methods for the measurement of seeing, and techniques for minimizing image-degrading effects of the atmosphere. 279 references

  15. Preparing Colorful Astronomical Images and Illustrations

    Science.gov (United States)

    Levay, Z. G.; Frattare, L. M.

    2001-12-01

    We present techniques for using mainstream graphics software, specifically Adobe Photoshop and Illustrator, for producing composite color images and illustrations from astronomical data. These techniques have been used with numerous images from the Hubble Space Telescope to produce printed and web-based news, education and public presentation products as well as illustrations for technical publication. While Photoshop is not intended for quantitative analysis of full dynamic range data (as are IRAF or IDL, for example), we have had much success applying Photoshop's numerous, versatile tools to work with scaled images, masks, text and graphics in multiple semi-transparent layers and channels. These features, along with its user-oriented, visual interface, provide convenient tools to produce high-quality, full-color images and graphics for printed and on-line publication and presentation.

  16. Dacic Ancient Astronomical Research in Sarmizegetuza

    Directory of Open Access Journals (Sweden)

    Emanuel George Oprea

    2015-11-01

    Full Text Available The actual Romanian territory belongs to Carpatho-Danubian Space and to Ancient Europe. The Ancient European Society was a vast cultural entity based on a theocratic, matriarchal society, peaceful and art creating.Temples of Sarmizegetusa have given rise to several theories over time, proven by historians with the most diverse arguments. The largest complex of temples and sanctuaries was founded in Sarmizegetusa Regia, the Dacian’s main fortress and ancient capital of Dacia in the time of King Decebalus. The mysterious form of settlements has led researchers to the conclusion that the locations were astronomical observation shrines. Among the places of Dacian worship in Orastie Mountains the most impressive is the Great Circular Sanctuary, used to perform some celestial observations, and also as original solar calendar. This paper had the purpose to re-discover the Dacian Civilization and Dacian cosmogony based on the accumulated knowledge upon our country’s past.

  17. The Infrared Astronomical Satellite (IRAS) mission

    Science.gov (United States)

    Neugebauer, G.; Habing, H. J.; Van Duinen, R.; Aumann, H. H.; Beichman, C. A.; Baud, B.; Beintema, D. A.; Boggess, N.; Clegg, P. E.; De Jong, T.

    1984-01-01

    The Infrared Astronomical Satellite (IRAS) consists of a spacecraft and a liquid helium cryostat that contains a cooled IR telescope. The telescope's focal plane assembly is cooled to less than 3 K, and contains 62 IR detectors in the survey array which are arranged so that every source crossing the field of view can be seen by at least two detectors in each of four wavelength bands. The satellite was launched into a 900 km-altitude near-polar orbit, and its cryogenic helium supply was exhausted on November 22, 1983. By mission's end, 72 percent of the sky had been observed with three or more hours-confirming scans, and 95 percent with two or more hours-confirming scans. About 2000 stars detected at 12 and 25 microns early in the mission, and identified in the SAO (1966) catalog, have a positional uncertainty ellipse whose axes are 45 x 9 arcsec for an hours-confirmed source.

  18. Astronomical knowledge transmission through illustrated Aratea manuscripts

    CERN Document Server

    Dolan, Marion

    2017-01-01

    This carefully researched monograph is a historical investigation of the illustrated Aratea astronomical manuscript and its many interpretations over the centuries. Aratus' 270 B.C.E. Greek poem describing the constellations and astrological phenomena was translated and copied over 800 years into illuminated manuscripts that preserved and illustrated these ancient stories about the constellations. The Aratea survives in its entirety due to multiple translations from Greek to Latin and even to Arabic, with many illuminated versions being commissioned over the ages. The survey encompasses four interrelated disciplines: history of literature, history of myth, history of science, and history of art. Aratea manuscripts by their nature are a meeting place of these distinct branches, and the culling of information from historical literature and from the manuscripts themselves focuses on a wider, holistic view; a narrow approach could not provide a proper prospective. What is most essential to know about this work is...

  19. Effectiveness of Amateur Astronomers as Informal Science Educators

    Science.gov (United States)

    Gibbs, Michael G.; Berendsen, Margaret

    2007-01-01

    The Astronomical Society of the Pacific (ASP) conducted a national survey of in-service teachers participating in Project ASTRO. The survey results document (1) the value that teachers place on supplemental astronomy education provided by professional and amateur astronomers, and (2) the difference that teachers perceive in the value provided by…

  20. Rosuvastatin for Primary Prevention in Older Persons With Elevated C-Reactive Protein and Low to Average Low-Density Lipoprotein Cholesterol Levels: Exploratory Analysis of a Randomized Trial

    DEFF Research Database (Denmark)

    Glynn, R.J.; Koenig, W.; Nordestgaard, B.G.

    2010-01-01

    or older. Design: Secondary analysis of JUPITER ( Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin), a randomized, double-blind, placebo-controlled trial. Setting: 1315 sites in 26 countries randomly assigned participants in JUPITER. Participants: Among......Background: Randomized data on statins for primary prevention in older persons are limited, and the relative hazard of cardiovascular disease associated with an elevated cholesterol level weakens with advancing age. Objective: To assess the efficacy and safety of rosuvastatin in persons 70 years...... assigned in a 1: 1 ratio to receive 20 mg of rosuvastatin daily or placebo. Measurements: The primary end point was the occurrence of a first cardiovascular event ( myocardial infarction, stroke, arterial revascularization, hospitalization for unstable angina, or death from cardiovascular causes). Results...

  1. Proceedings of the VI Serbian-Bulgarian Astronomical Conference, May 7 - 11 2008, Belgrade, Serbia

    Science.gov (United States)

    Dimitrijević, M. S.; Tsvetkov, M.; Popović, L. C.; Golev, V.

    2009-07-01

    The Sixth Serbian-Bulgarian Astronomical Conference was organized by Belgrade Astronomical Observatory, and held in Belgrade, in the building of Mathematical Faculty in Jagiceva Street, from 75th to 11th May 2008. Co-organizers were Mathematical Faculty, Astronomical Society "Rudjer Boskovic", Institute of Astronomy of the Bulgarian Academy of Sciences (BAS), Space Research Institute of BAS and Department of Astronomy of the University of Sofia. Co-chairmen of the Scientific Organizing Committee were Milan Dimitrijevic and Milcho Tsvetkov and Co-vice chairmen Luka C. Popovic and Valeri Golev. Chair of the Local Organizing Committee was Andjelka Kovacevic. The conference [was] attended by 58 participants. From Serbia were 36, from Belgrade Astronomical Observatory, Mathematical Faculty, Faculty of Sciences from Nis, Institute of Physics from Zemum, High School for pedagogues of occupational studies from Aleksinac, Faculty of Sciences from Kragujevac, Mathematical Institute of Serbian Academy of Sciences and Arts, Astronomical Society "Rudjer Boskovic" and Astronomical Society "Magellanic Cloud." From Bulgaria were present 17 colleagues: Svetlana Boeva, Ana Borisova, Momchil Dechev, Peter Duchlev, Lostadinka Koleva, Georgi Petrov, Vasil Popov, Konstatin Stavrev, Katya Ysvetkova and Milcho Tsvetkov from Institute of Astronomy of BAS, Rumen Bogdanovski and Krasmimira Ianova from Space Research Institute of BAS, Georgi R. Ivanov, Georgi Petrov and Grigor Nikolov from Department of Astronomy, Sofia University "St Kliment Ohridski,", Yavor Chapanov from Central Laboratory for Geodesy of BAS and Petya Pavlova from Technical University of Sofia, Branch Plovdiv. Besides participants from Serbia and Bulgaria the Conference [was] attended [by] Vlado Milicevic from Canada, Jan Vondrak from Czech Republic, Aytap Sezer from Turkey and Tetyana Sergeeva and Alexandr Sergeev from Ukraine. On the Conference were presented 13 invited lectures, 22 short talks and 35 posters, in total

  2. Astronomers Discover Fastest-Spinning Pulsar

    Science.gov (United States)

    2006-01-01

    Astronomers using the National Science Foundation's Robert C. Byrd Green Bank Telescope have discovered the fastest-spinning neutron star ever found, a 20-mile-diameter superdense pulsar whirling faster than the blades of a kitchen blender. Their work yields important new information about the nature of one of the most exotic forms of matter known in the Universe. Pulsar Graphic Pulsars Are Spinning Neutron Stars CREDIT: Bill Saxton, NRAO/AUI/NSF (Click on image for larger version) "We believe that the matter in neutron stars is denser than an atomic nucleus, but it is unclear by how much. Our observations of such a rapidly rotating star set a hard upper limit on its size, and hence on how dense the star can be.," said Jason Hessels, a graduate student at McGill University in Montreal. Hessels and his colleagues presented their findings to the American Astronomical Society's meeting in Washington, DC. Pulsars are spinning neutron stars that sling "lighthouse beams" of radio waves or light around as they spin. A neutron star is what is left after a massive star explodes at the end of its "normal" life. With no nuclear fuel left to produce energy to offset the stellar remnant's weight, its material is compressed to extreme densities. The pressure squeezes together most of its protons and electrons to form neutrons; hence, the name "neutron star." "Neutron stars are incredible laboratories for learning about the physics of the fundamental particles of nature, and this pulsar has given us an important new limit," explained Scott Ransom, an astronomer at the National Radio Astronomy Observatory and one of Hessels' collaborators on this work. The scientists discovered the pulsar, named PSR J1748-2446ad, in a globular cluster of stars called Terzan 5, located some 28,000 light-years from Earth in the constellation Sagittarius. The newly-discovered pulsar is spinning 716 times per second, or at 716 Hertz (Hz), readily beating the previous record of 642 Hz from a pulsar

  3. Rosuvastatin Decreases Intestinal Fatty Acid Binding Protein (I-FABP), but Does Not Alter Zonulin or Lipopolysaccharide Binding Protein (LBP) Levels, in HIV-Infected Subjects on Antiretroviral Therapy.

    Science.gov (United States)

    Funderburg, Nicholas T; Boucher, Morgan; Sattar, Abdus; Kulkarni, Manjusha; Labbato, Danielle; Kinley, Bruce I; McComsey, Grace A

    2016-01-01

    Altered gastrointestinal (GI) barrier integrity and subsequent microbial translocation may contribute to immune activation in HIV infection. We have reported that rosuvastatin improved several markers of immune activation in HIV+ participants, but the effect of statin treatment on markers of GI barrier dysfunction is unknown. SATURN-HIV is a randomized, double-blind, placebo-controlled trial assessing the effect of rosuvastatin (10mg/daily) on markers of cardiovascular disease, inflammation, and immune activation in ART-treated patients. Gut-barrier integrity was assessed by the surrogate markers intestinal fatty acid binding protein (I-FABP), a marker of enterocyte death, and zonulin-1, a marker of gut epithelial cell function. Levels of lipopolysaccharide binding protein (LBP) were measured as a marker of microbial translocation. Rosuvastatin significantly reduced levels of I-FABP during the treatment period compared to the placebo. There was no effect of rosuvastatin treatment on levels of zonulin or LBP. Baseline levels of LBP were directly related to several markers of immune activation in samples from all participants, including soluble CD163, IP-10, VCAM-1, TNFR-II, and the proportion of CD4+ and CD8+ T cells expressing CD38 and HLA-DR. Many of these relationships, however, were not seen in the statin arm alone at baseline or over time, as inflammatory markers often decreased and LBP levels were unchanged. Forty-eight weeks of rosuvastatin treatment reduced levels of I-FABP, but did not affect levels of zonulin or LBP. The reduction in levels of inflammatory markers that we have reported with rosuvastatin treatment is likely mediated through other mechanisms not related to gut integrity or microbial translocation.

  4. 125th Colloquium of the International Astronomical Union

    CERN Document Server

    Sorochenko, R

    1990-01-01

    Text no 1 Radio Recombination Lines (RRLs), discovered in the USSR in 1964, have become a powerful research tool for astronomers. Available throughout the radio spectrum, these lines carry information regarding the density, temperature, turbulence and velocity of thermal plasmas. Their very existance shows the presence of thermal gas. They also can carry information regarding magnetic fields if Zeeman splitting were to be detected. Containing the proceedings of an IAU Colloquium celebrating the 25th anniversary of their detection, this volume tells us what has happened since. It contains the story of the detection of RRLs and reviews of many areas of physics of the interstellargas from which stars form, HII regions excited by newly formed stars, planetary nebulae involving dying stars, and the structure of our Milky Way and other galaxies reflecting the large-scale morphology of the star formation process. In addition there is an article describing modern laboratory studies of Rydberg atoms to probe the basic...

  5. Future Nuisance Flooding at Boston Caused by Astronomical Tides Alone

    Science.gov (United States)

    Ray, Richard D.; Foster, Grant

    2016-01-01

    Sea level rise necessarily triggers more occurrences of minor, or nuisance, flooding events along coastlines, a fact well documented in recent studies. At some locations nuisance flooding can be brought about merely by high spring tides, independent of storms, winds, or other atmospheric conditions. Analysis of observed water levels at Boston indicates that tidal flooding began to occur there in 2011 and will become more frequent in subsequent years. A compilation of all predicted nuisance-flooding events, induced by astronomical tides alone, is presented through year 2050. The accuracy of the tide prediction is improved when several unusual properties of Gulf of Maine tides, including secular changes, are properly accounted for. Future mean sea-level rise at Boston cannot be predicted with comparable confidence, so two very different climate scenarios are adopted; both predict a large increase in the frequency and the magnitude of tidal flooding events.

  6. Astronomers Reveal Extinct Extra-Terrestrial Fusion Reactor

    Science.gov (United States)

    2004-06-01

    An international team of astronomers, studying the left-over remnants of stars like our own Sun, have found a remarkable object where the nuclear reactor that once powered it has only just shut down. This star, the hottest known white dwarf, H1504+65, seems to have been stripped of its entire outer regions during its death throes leaving behind the core that formed its power plant. Scientists from the United Kingdom, Germany and the USA focused two of NASA's space telescopes, the Chandra X-ray Observatory and the Far Ultraviolet Spectroscopic Explorer (FUSE), onto H1504+65 to probe its composition and measure its temperature. The data revealed that the stellar surface is extremely hot, 200,000 degrees, and is virtually free of hydrogen and helium, something never before observed in any star. Instead, the surface is composed mainly of carbon and oxygen, the 'ashes' of the fusion of helium in a nuclear reactor. An important question we must answer is why has this unique star lost the hydrogen and helium, which usually hide the stellar interior from our view? Professor Martin Barstow (University of Leicester) said. 'Studying the nature of the ashes of dead stars give us important clues as to how stars like the Sun live their lives and eventually die. The nuclear waste of carbon and oxygen produced in the process are essential elements for life and are eventually recycled into interstellar space to form new stars, planets and, possibly, living beings.' Professor Klaus Werner (University of Tübingen) said. 'We realized that this star has, on astronomical time scales, only very recently shut down nuclear fusion (about a hundred years ago). We clearly see the bare, now extinct reactor that once powered a bright giant star.' Dr Jeffrey Kruk (Johns Hopkins University) said: 'Astronomers have long predicted that many stars would have carbon-oxygen cores near the end of their lives, but I never expected we would actually be able to see one. This is a wonderful opportunity to

  7. Knowing the people who come to public astronomical observatories: The case of Akita prefecture, Japan

    Science.gov (United States)

    Kawamura, N.

    2015-03-01

    The purpose of this research is to know and gain a better understanding of people who come to astronomical observatories and to find out more about their experiences and thoughts on astronomy. To find some of the issues about science communication in astronomy, the author carried out questionnaire research studies involving high school students and junior high school and elementary school teachers.

  8. [Terhi Kiiskinen. Sigfrid Aronus Forsius : Astronomer and Philosopher of Nature] / Liivi Aarma

    Index Scriptorium Estoniae

    Aarma, Liivi, 1948-

    2009-01-01

    Arvustus: Kiiskinen, Terhi. Sigfrid Aronus Forsius : Astronomer and Philosopher of Nature. Europäische Studien zur Ideen- und Wissenschaftsgeschichte / Europaen Studies in the History of Science and Ideas. Hrsg. von / edited by Georg Gimpi und Juha Manninen. Frankfurt am Main, 2007. Sigfrid Aronus Forsius on tuntuim Põhjamaade renesanssi aegne Rootsi kuningriigi teadlane

  9. NRAO Astronomer Wins Prestigious Guggenheim Fellowship

    Science.gov (United States)

    2010-04-01

    Dr. Dale Frail, an astronomer at the National Radio Astronomy Observatory (NRAO) in Socorro, New Mexico, has been awarded a prestigious Guggenheim Fellowship, according to the John Simon Guggenheim Memorial Foundation. The Guggenheim Foundation describes its fellowships as "mid-career" awards "intended for men and women who have already demonstrated exceptional capacity for productive scholarship or exceptional creative ability in the arts." Frail, 48, has worked at the NRAO for more than 20 years, first as a postdoctoral fellow, and then as a staff scientist. He received his bachelor's degree in physics from Acadia University in Nova Scotia, and his Ph.D in astronomy from the University of Toronto. Frail is best known for his landmark contributions to the understanding of gamma ray bursts, making critical measurements that provided key insights into the mechanisms of these superenergetic and once-mysterious explosions. He also has made important contributions to the understanding of other astronomical phenomena, including pulsars and their neighborhoods, supernova remnants, and magnetars. In 1992, he was the co-discoverer, with Alex Wolszczan, of the first planets outside our own solar system. "We congratulate Dale on this well-deserved honor that recognizes not only his past achievements but also his potential for exciting scientific work in the future," said Dr. Fred K.Y. Lo, NRAO Director. "We're very proud to see one of our scientists receive such a great honor," Lo added. Frail is one of 180 recipients of this year's Guggenheim Fellowships, chosen from some 3,000 applicants. The fellowships were established in 1925 and past recipients include photographer Ansel Adams, author Saul Bellow, former Secretary of State Henry Kissinger, and chemist Linus Pauling. 102 Guggenheim Fellows have subsequently won Nobel Prizes, and others have received Pulitzer Prizes and other honors. As a Guggenheim Fellow, Frail intends to intensify his research in the areas of pulsars

  10. Radio Astronomers Get Their First Glimpse of Powerful Solar Storm

    Science.gov (United States)

    2001-08-01

    Astronomers have made the first radio-telescope images of a powerful coronal mass ejection on the Sun, giving them a long-sought glimpse of hitherto unseen aspects of these potentially dangerous events. "These observations are going to provide us with a new and unique tool for deciphering the mechanisms of coronal mass ejections and how they are related to other solar events," said Tim Bastian, an astronomer at the National Science Foundation's National Radio Astronomy Observatory (NRAO) in Charlottesville, Virginia. Radio image of coronal mass ejection; circle indicates the size and location of the Sun. White dots are where radio spectral measurements were made. Bastian, along with Monique Pick, Alain Kerdraon and Dalmiro Maia of the Paris Observatory, and Angelos Vourlidas of the Naval Research Laboratory in Washington, D.C., used a solar radio telescope in Nancay, France, to study a coronal mass ejection that occurred on April 20, 1998. Their results will be published in the September 1 edition of the Astrophysical Journal Letters. Coronal mass ejections are powerful magnetic explosions in the Sun's corona, or outer atmosphere, that can blast billions of tons of charged particles into interplanetary space at tremendous speeds. If the ejection is aimed in the direction of Earth, the speeding particles interact with our planet's magnetic field to cause auroral displays, radio-communication blackouts, and potentially damage satellites and electric-power systems. "Coronal mass ejections have been observed for many years, but only with visible-light telescopes, usually in space. While previous radio observations have provided us with powerful diagnostics of mass ejections and associated phenomena in the corona, this is the first time that one has been directly imaged in wavelengths other than visible light," Bastian said. "These new data from the radio observations give us important clues about how these very energetic events work," he added. The radio images show an

  11. Book Review: Scientific Writing for Young Astronomers

    Science.gov (United States)

    Uyttenhove, Jos

    2011-12-01

    EDP Sciences, Les Ulis, France. Part 1 : 162 pp. € 35 ISBN 978-2-7598-0506-8 Part 2 : 298 pp. € 60 ISBN 978-2-7598-0639-3 The journal Astronomy & Astrophysics (A&A) and EDP Sciences decided in 2007 to organize a School on the various aspects of scientific writing and publishing. In 2008 and 2009 Scientific Writing for Young Astronomers (SWYA) Schools were held in Blankenberge (B) under the direction of Christiaan Sterken (FWO-VUB). These two books (EAS publication series, Vol. 49 and 50) reflect the outcome of these Schools. Part 1 contains a set of contributions that discuss various aspects of scientific publication; it includes A&A Editors' view of the peer review and publishing process. A very interesting short paper by S.R. Pottasch (Kapteyn Astronomical Institute, Groningen, and one of the two first Editors-in Chief of A&A) deals with the history of the creation of the journal Astronomy & Astrophysics. Two papers by J. Adams et al. (Observatoire de Paris) discuss language editing, including a detailed guide for any non-native user of the English language. In 2002 the Board of Directors decided that all articles in A&A must be written in clear and correct English. Part 2 consists of three very extensive and elaborated papers by Christiaan Sterken, supplying guidelines to PhD students and postdoctoral fellows to help them compose scientific papers for different forums (journals, proceedings, thesis, etc.). This part is of interest not only for young astronomers but it is very useful for scholars of all ages and disciplines. Paper I "The writing process" (60 pp.) copes with the preparation of manuscripts, with communicating with editors and referees and with avoiding common errors. Delicate problems on authorship, refereeing, revising multi-authored papers etc. are treated in 26 FAQ's. Paper II "Communication by graphics" (120 pp.) is entirely dedicated to the important topic of communication with images, graphs, diagrams, tables etc. Design types of graphs

  12. Electronic Publishing and The American Astronomical Society

    Science.gov (United States)

    Milkey, R. W.

    1999-12-01

    Electronic Publishing has created, and will continue to create, new opportunities and challenges for representing scientific work in new media and formats. The AAS will position itself to take advantage of these, both for newly created works and for improved representation of works already published. It is the view of the AAS that we hold the works that we publish in trust for our community and are obligated to protect the integrity of these works and to assure that they continue to be available to the research community. Assignment of copyright to the AAS by the author plays a central role in the preservation of the integrity and accessability of the literature published by the American Astronomical Society. In return for such assignment the AAS allows the author to freely use the work for his/her own purpose and to control the grant of permission to third parties to use such materials. The AAS retains the right to republish the work in whatever format or medium, and to retain the rights after the author's death. Specific advantages to this approach include: Assurance of the continued availability of the materials to the research and educational communities; A guarantee of the intellectual integrity of the materials in the archive; Stimulation of the development of new means of presentation or of access to the archival literature; and Provision of a uniformity of treatment for copyright issues and to relieve the individual authors of much of the administrative work.

  13. Is astronomical research appropriate for developing countries?

    Science.gov (United States)

    Snowden, Michael S.

    An unproductive 45-cm astronomical telescope, given by JICA (Japan) to Sri Lanka, raises general questions as to the reasons for unproductive pure science in developing countries. Before installation, site, maintenance, and scientific objectives were discussed. The facility was launched with a conference organised by the UN Office for Outer Space Affairs. Unfortunately, no research or significant education has resulted after four years. The annual operating cost is U.S. $5000 per year, including salary for a trainee, maintenance, and a modest promotional programme. Comparison with a similar installation in Auckland suggests lack of funding or technical competence do not explain the failure in Sri Lanka. The facility in New Zealand, on the roof of Auckland University's Physics Department, has a slightly smaller budget but has led to modest but useful research and teaching. Lack of financial backing and expertise are often blamed for weak science in developing countries, but examination shows most of these countries have adequately skilled people, and plenty of resources for religion and military. General lack of motivation for science appears to be the principal reason. This lack of interest and highly inefficient bureaucracies are common to scientifically unproductive countries. They mostly lack the cultural and philosophical base of the European Renaissance that motivate the pursuit of modern science, an activity that violates human preferences. There are excellent facilities (ESO, SAAO, Cerro Tololo, and GONG) in some of these same countries, when administered from the West.

  14. Serbian Astronomers in Science Citation Index in the XX Century

    Science.gov (United States)

    Dimitrijevic, Milan S.

    The book is written paralelly in Serbian and English. The presence of works of Serbian astronomers and works in astronomical journals published by other Serbian scientists, in Science Citation Index within the period from 1945 up to the end of 2000, has been analyzed. Also is presented the list of 38 papers which had some influence on the development of astronomy in the twentieth century. A review of the development of astronomy in Serbia in the last century is given as well. Particular attention is payed to the Astronomical Observatory, the principal astronomical institution in Serbia, where it is one of the oldest scientific organizations and the only autonomous astronomical institute. Its past development forms an important part of the history of science and culture in these regions. In the book is also considered and the history of the university teaching of astronomy in Serbia after the second world war. First of all the development of the Chair of Astronomy at the Faculty of Mathematics in Belgrade, but also the teaching of astronomy at University in Novi Sad, Ni and Kragujevac is discussed. In addition to professional Astronomy, well developed in Serbia is also the amateur Astronomy. In the review is first of all included the largest and the oldest organization of amateur-astronomers in Serbia, founded in 1934. Besides, here are the Astronomical Society "Novi Sad", ADNOS and Research Station "Petnica". In Valjevo, within the framework of the Society of researchers "Vladimir Mandic - Manda", there is active also the Astronomical Group. In Kragujevac, on the roof of the Institute of Physics of the Faculty of Sciences, there is the "Belerofont" Observatory. In Ni, at the close of the sixties and the start of the seventies, there was operating a branch of the Astronomical Society "Rudjer Bokovic", while at the Faculty of Philosophy there existed in the period 1976-1980 the "Astro-Geophysical Society". In the year 1996 there was founded Astronomical Society

  15. Astronomical Observatory of Belgrade from 1924 to 1955

    Science.gov (United States)

    Radovanac, M.

    2014-12-01

    History of the Astronomical Observatory in Belgrade, as the presentation is done here, become the field of interest to the author of the present monograph in early 2002. Then, together with Luka C. Popovic, during the Conference "Development of Astronomy among Serbs II" held in early April of that year, he prepared a paper entitled "Astronomska opservatorija tokom Drugog Svetskog rata" (Astronomical Observatory in the Second World War). This paper was based on the archives material concerning the Astronomical Observatory which has been professionally bearing in mind the author's position the subject of his work.

  16. Conducting Original, Hands-On Astronomical Research in the Classroom

    Science.gov (United States)

    Corneau, M. J.

    2009-12-01

    teachers to convey moderately complex computer science, optical, geographic, mathematical, informational and physical principles through hands-on telescope operations. In addition to the general studies aspects of classroom internet-based astronomy, Tzec Maun supports real science by enabling operators precisely point telescopes and acquire extremely faint, magnitude 19+ CCD images. Thanks to the creative Team of Photometrica (photometrica.org), my teams now have the ability to process and analyze images online and produce results in short order. Normally, astronomical data analysis packages cost greater than thousands of dollars for single license operations. Free to my team members, Photometrica allows students to upload their data to a cloud computing server and read precise photometric and/or astrometric results. I’m indebted to Michael and Geir for their support. The efficacy of student-based research is well documented. The Council on Undergraduate Research defines student research as, "an inquiry or investigation conducted by an undergraduate that makes an original intellectual or creative contribution to the discipline." (http://serc.carleton.edu/introgeo/studentresearch/What. Teaching from Tzec Maun in the classroom is the most original teaching research I can imagine. I very much look forward to presenting this program to the convened body.

  17. An Astronomer In The Classroom: Observatoire de Paris's Partnership Between Teachers and Astronomers

    Science.gov (United States)

    Doressoundiram, A.; Barban, C.

    2006-08-01

    The Observatoire de Paris is offering a partnership between teachers and astronomers. The principle is simple: any teacher wishing to undertake a pedagogical project in astronomy, in the classroom or involving the entire school, can request the help of a mentor. An astronomer from the Observatoire de Paris will then follow the teacher's project progress and offer advice and scientific support throughout the school year. The projects may take different forms: construction projects (models, instruments), lectures, posters, exhibitions, etc. The type of assistance offered is as varied as the projects: lecture(s) in class, telephone and e-mail exchanges, visits to the Observatoire; an almost made-to-measure approach that delighted the thirty or so groups that benefited such partnership in the 2005-2006 academic year. And this number is continuously growing. There was a rich variety of projects undertaken, from mounting a show and building a solar clock to visiting a high altitude observatory, or resolving the mystery of Jupiter's great red spot. The Universe and its mysteries fascinate the young (and the not so- young) and provide a multitude of scientific topics that can be exploited in class. Astronomy offers the added advantage of being a multidisciplinary field. Thus, if most projects are generally initiated by a motivated teacher, they are often taken over by teachers in other subjects: Life and Earth Sciences (SVT), history, mathematics, French, and so forth. The project may consist in an astronomy workshop or be part of the school curriculum. Whatever the case, the astronomer's task is not to replace the teacher or the textbooks, but to propose activities or experiments that are easy to implement. Representing the Solar system on a school-yard scale, for instance, is a perfect way to make youngsters realize that the Universe consists mostly of empty space. There is no shortage of topics, and the students' enthusiasm, seldom absent, is the best reward for the

  18. Strategies for personnel sustainable lifecycle at astronomical observatories and local industry development

    Science.gov (United States)

    Bendek, Eduardo A.; Leatherbee, Michael; Smith, Heather; Strappa, Valentina; Zinnecker, Hans; Perez, Mario

    2014-08-01

    Specialized manpower required to efficiently operate world-class observatories requires large investments in time and resources to train personnel in very specific areas of engineering. Isolation and distances to mayor cities pose a challenge to retain motivated and qualified personnel on the mountain. This paper presents strategies that we believe may be effective for retaining this specific know-how in the astronomy field; while at the same time develop a local support industry for observatory operations and astronomical instrumentation development. For this study we choose Chile as a research setting because it will host more than 60% of the world's ground based astronomical infrastructure by the end of the decade, and because the country has an underdeveloped industry for astronomy services. We identify the astronomical infrastructure that exists in the country as well as the major research groups and industrial players. We further identify the needs of observatories that could be outsourced to the local economy. As a result, we suggest spin-off opportunities that can be started by former observatory employees and therefore retaining the knowhow of experienced people that decide to leave on-site jobs. We also identify tools to facilitate this process such as the creation of a centralized repository of local capabilities and observatory needs, as well as exchange programs within astronomical instrumentation groups. We believe that these strategies will contribute to a positive work environment at the observatories, reduce the operation and development costs, and develop a new industry for the host country.

  19. Astronomers Trace Microquasar's Path Back in Time

    Science.gov (United States)

    2003-01-01

    Astronomers have traced the orbit through our Milky Way Galaxy of a voracious neutron star and a companion star it is cannibalizing, and conclude that the pair joined more than 30 million years ago and probably were catapulted out of a cluster of stars far from the Galaxy's center. Path of Microquasar and Sun Path of Microquasar (red) and Sun (yellow) through the Milky Way Galaxy for the past 230 million years. Animations: GIF Version MPEG Version CREDIT: Mirabel & Rodrigues, NRAO/AUI/NSF The pair of stars, called Scorpius X-1, form a "microquasar," in which material sucked from the "normal" star forms a rapidly-rotating disk around the superdense neutron star. The disk becomes so hot it emits X-rays, and also spits out "jets" of subatomic particles at nearly the speed of light. Using precise positional data from the National Science Foundation's Very Long Baseline Array (VLBA) and from optical telescopes, Felix Mirabel, an astrophysicist at the Institute for Astronomy and Space Physics of Argentina and French Atomic Energy Commission, and Irapuan Rodrigues, also of the French Atomic Energy Commission, calculated that Scorpius X-1 is not orbiting the Milky Way's center in step with most other stars, but instead follows an eccentric path far above and below the Galaxy's plane. Scorpius X-1, discovered with a rocket-borne X-ray telescope in 1962, is about 9,000 light-years from Earth. It is the brightest continuous source of X-rays beyond the Solar System. The 1962 discovery and associated work earned a share of the 2002 Nobel Prize in physics for Riccardo Giacconi. Mirabel and Rodrigues used a number of published observations to calculate the path of Scorpius X-1 over the past few million years. "This is the most accurate determination we have made of the path of an X-ray binary," said Mirabel. By tracing the object's path backward in time, the scientists were able to conclude that the neutron star and its companion have been traveling together for more than 30

  20. Spectroscopy for amateur astronomers recording, processing, analysis and interpretation

    CERN Document Server

    Trypsteen , Marc F M

    2017-01-01

    This accessible guide presents the astrophysical concepts behind astronomical spectroscopy, covering both the theory and the practical elements of recording, processing, analysing and interpreting your spectra. It covers astronomical objects, such as stars, planets, nebulae, novae, supernovae, and events such as eclipses and comet passages. Suitable for anyone with only a little background knowledge and access to amateur-level equipment, the guide's many illustrations, sketches and figures will help you understand and practise this scientifically important and growing field of amateur astronomy, up to the level of Pro-Am collaborations. Accessible to non-academics, it benefits many groups from novices and learners in astronomy clubs, to advanced students and teachers of astrophysics. This volume is the perfect companion to the Spectral Atlas for Amateur Astronomers, which provides detailed commented spectral profiles of more than 100 astronomical objects.

  1. Astronomical sketching a step-by-step introduction

    CERN Document Server

    Handy, Richard; Perez, Jeremy; Rix, Erika; Robbins, Sol

    2007-01-01

    This book presents the amateur with fine examples of astronomical sketches and step-by-step tutorials in each medium, from pencil to computer graphics programs. This unique book can teach almost anyone to create beautiful sketches of celestial objects.

  2. Database retrieval systems for nuclear and astronomical data

    International Nuclear Information System (INIS)

    Suda, Takuma; Korennov, Sergei; Otuka, Naohiko; Yamada, Shimako; Katsuta, Yutaka; Ohnishi, Akira; Kato, Kiyoshi; Fujimoto, Masayuki Y.

    2006-01-01

    Data retrieval and plot systems of nuclear and astronomical data are constructed on a common platform. Web-based systems will soon be opened to the users of both fields of nuclear physics and astronomy. (author)

  3. PPARC: Grid technology helps astronomers keep pace with the Universe

    CERN Multimedia

    2003-01-01

    "Intelligent Agent" computer programs are roaming the Internet and watching the skies. These programs, using Grid computing technology, will help astronomers detect some of the most dramatic events in the universe, such as massive supernova explosions (1 page).

  4. The Educational Activities of the Astronomical Society of the Pacific.

    Science.gov (United States)

    Fraknoi, Andrew

    1981-01-01

    Describes educational activities of the Astronomical Society of the Pacific including learning packets on various astronomy concepts, Morrison lectures, newspaper columns, teacher workshops, cosponsoring astronomy oriented lectures, and providing speakers for various groups. (DS)

  5. High energy astrophysics in radio-astronomical form

    International Nuclear Information System (INIS)

    Laan, H. van der

    1980-01-01

    The application of high energy astrophysics in observational astronomy, and in particular in radioastronomy, is considered. The current situation of extragalactic HEA, as brought to light by radio-astronomical techniques, is sketched. (C.F.)

  6. Lessons from the masters current concepts in astronomical image processing

    CERN Document Server

    2013-01-01

    There are currently thousands of amateur astronomers around the world engaged in astrophotography at increasingly sophisticated levels. Their ranks far outnumber professional astronomers doing the same and their contributions both technically and artistically are the dominant drivers of progress in the field today. This book is a unique collaboration of individuals, all world-renowned in their particular area, and covers in detail each of the major sub-disciplines of astrophotography. This approach offers the reader the greatest opportunity to learn the most current information and the latest techniques directly from the foremost innovators in the field today.   The book as a whole covers all types of astronomical image processing, including processing of eclipses and solar phenomena, extracting detail from deep-sky, planetary, and widefield images, and offers solutions to some of the most challenging and vexing problems in astronomical image processing. Recognized chapter authors include deep sky experts su...

  7. Astronomical fire: Richard Carrington and the solar flare of 1859.

    Science.gov (United States)

    Clark, Stuart

    2007-09-01

    An explosion on the Sun in 1859, serendipitously witnessed by amateur astronomer Richard Carrington, plunged telegraphic communications into chaos and bathed two thirds of the Earth's skies in aurorae. Explaining what happened to the Sun and how it could affect Earth, 93 million miles away, helped change the direction of astronomy. From being concerned principally with charting the stars to aid navigation, astronomers became increasingly concerned with what the celestial objects were, how they behaved and how they might affect life on Earth.

  8. ARNICA, the Arcetri near-infrared camera: Astronomical performance assessment.

    Science.gov (United States)

    Hunt, L. K.; Lisi, F.; Testi, L.; Baffa, C.; Borelli, S.; Maiolino, R.; Moriondo, G.; Stanga, R. M.

    1996-01-01

    The Arcetri near-infrared camera ARNICA was built as a users' instrument for the Infrared Telescope at Gornergrat (TIRGO), and is based on a 256x256 NICMOS 3 detector. In this paper, we discuss ARNICA's optical and astronomical performance at the TIRGO and at the William Herschel Telescope on La Palma. Optical performance is evaluated in terms of plate scale, distortion, point spread function, and ghosting. Astronomical performance is characterized by camera efficiency, sensitivity, and spatial uniformity of the photometry.

  9. Preservation and maintenance of the astronomical sites in Armenia

    Science.gov (United States)

    Mickaelian, A. M.

    2008-01-01

    Astronomy in Armenia was popular since ancient times. There are signs of astronomical observations coming from a few thousands years ago. Two ancient observatories, Karahunge and Metzamor are especially well known. Karahunge is the Armenian twin of the Stonehenge and is even older. However, there is no proper attention from the state authorities and efforts are needed for preservation of such historical-astronomical monuments. The Byurakan Astrophysical Observatory (BAO) is the modern famous Armenian observatory founded in 1946 by the outstanding scientist Victor Ambartsumian. It was one of the world astronomical centres in 1950-s to 1970-s, and at present is the largest observatory in the Middle East area. As the ancient astronomical sites, Byurakan also needs a proper attitude from the state authorities and corresponding international organizations to preserve its values and importance for the present and future astronomical activities in the region, including its rich observational archive, telescopes, and human resources. Despite all the difficulties, the Armenian astronomers keep high international level of research and display various activities organizing international meetings and schools, preparing new young generation for the future research. The Armenian Astronomical Society (ArAS) is an affiliated member of EAS. Armenia has its Virtual Observatory project (ArVO) as well. The next Joint European and National Astronomy Meeting (JENAM-2007) will be held in Yerevan, Armenia, in August 2007. There are plans to organize astronomical tours to Armenia for making observations from various sites, including the ancient observatories. The future of astronomy in Armenia strongly depends on all of this activities and the proper attention both from state authorities and society.

  10. Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey

    Directory of Open Access Journals (Sweden)

    Kones R

    2011-06-01

    prevention, cardiovascular risk, coronary heart disease, primordial prevention, rosuvastatin, JUPITER study, statin drugs, C-reactive protein, inflammation, low-density lipoprotein, high-density lipoprotein, diabetes, metabolic syndrome, Framingham risk score, Reynolds risk score, SCORE, coronary artery calcification, carotid intima-media thickness, hypertension, obesity, non-HDL-cholesterol, LDL-P, dysfunctional HDL, lifetime risk, advanced lipid testing, Bogalusa Heart Study

  11. Sports Stars: Analyzing the Performance of Astronomers at Visualization-based Discovery

    Science.gov (United States)

    Fluke, C. J.; Parrington, L.; Hegarty, S.; MacMahon, C.; Morgan, S.; Hassan, A. H.; Kilborn, V. A.

    2017-05-01

    In this data-rich era of astronomy, there is a growing reliance on automated techniques to discover new knowledge. The role of the astronomer may change from being a discoverer to being a confirmer. But what do astronomers actually look at when they distinguish between “sources” and “noise?” What are the differences between novice and expert astronomers when it comes to visual-based discovery? Can we identify elite talent or coach astronomers to maximize their potential for discovery? By looking to the field of sports performance analysis, we consider an established, domain-wide approach, where the expertise of the viewer (i.e., a member of the coaching team) plays a crucial role in identifying and determining the subtle features of gameplay that provide a winning advantage. As an initial case study, we investigate whether the SportsCode performance analysis software can be used to understand and document how an experienced Hi astronomer makes discoveries in spectral data cubes. We find that the process of timeline-based coding can be applied to spectral cube data by mapping spectral channels to frames within a movie. SportsCode provides a range of easy to use methods for annotation, including feature-based codes and labels, text annotations associated with codes, and image-based drawing. The outputs, including instance movies that are uniquely associated with coded events, provide the basis for a training program or team-based analysis that could be used in unison with discipline specific analysis software. In this coordinated approach to visualization and analysis, SportsCode can act as a visual notebook, recording the insight and decisions in partnership with established analysis methods. Alternatively, in situ annotation and coding of features would be a valuable addition to existing and future visualization and analysis packages.

  12. Astronomical Data Integration Beyond the Virtual Observatory

    Science.gov (United States)

    Lemson, G.; Laurino, O.

    2015-09-01

    "Data integration" generally refers to the process of combining data from different source data bases into a unified view. Much work has been devoted in this area by the International Virtual Observatory Alliance (IVOA), allowing users to discover and access databases through standard protocols. However, different archives present their data through their own schemas and users must still select, filter, and combine data for each archive individually. An important reason for this is that the creation of common data models that satisfy all sub-disciplines is fraught with difficulties. Furthermore it requires a substantial amount of work for data providers to present their data according to some standard representation. We will argue that existing standards allow us to build a data integration framework that works around these problems. The particular framework requires the implementation of the IVOA Table Access Protocol (TAP) only. It uses the newly developed VO data modelling language (VO-DML) specification, which allows one to define extensible object-oriented data models using a subset of UML concepts through a simple XML serialization language. A rich mapping language allows one to describe how instances of VO-DML data models are represented by the TAP service, bridging the possible mismatch between a local archive's schema and some agreed-upon representation of the astronomical domain. In this so called local-as-view approach to data integration, “mediators" use the mapping prescriptions to translate queries phrased in terms of the common schema to the underlying TAP service. This mapping language has a graphical representation, which we expose through a web based graphical “drag-and-drop-and-connect" interface. This service allows any user to map the holdings of any TAP service to the data model(s) of choice. The mappings are defined and stored outside of the data sources themselves, which allows the interface to be used in a kind of crowd-sourcing effort

  13. IYL Blog: Astronomers travel in time and space with light

    Science.gov (United States)

    Mather, John C.

    2015-01-01

    also using light to find out whether we are alone in the universe. The Kepler observatory showed that thousands of stars blink a little when their orbiting planets pass between us and them, and other observatories use light to measure the wobble of stars as their planets pull on them. Eventually, we will find out whether planets like Earth have atmospheres like Earth's too - with water, carbon dioxide, oxygen, methane, and other gases that would be evidence of photosynthetic life. I think in a few decades we will have evidence that some planets do have life, and it will be done using light for remote chemical analysis. Also, astronomers at the SETI project are using light (long wavelength light we can pick up with radio telescopes) to look for signals from intelligent civilizations. That's a harder project because we don't know what to look for. But if we wanted to send signals all the way across the Milky Way, we could do it with laser beams, and if somebody over there knew what to look for, he or she could decode the message. On with the search! Dr. John C. Mather is a Senior Astrophysicist and is the Senior Project Scientist for the James Webb Space Telescope at NASA's Goddard Space Flight Center in Greenbelt, MD. His research centers on infrared astronomy and cosmology. With the Cosmic Background Explorer (COBE) team, he showed that the cosmic microwave background radiation has a blackbody spectrum within 50 parts per million, confirming the expanding universe model (aka the Big Bang Theory) to extraordinary accuracy, and initiating the study of cosmology as a precision science. The COBE team also made the first map of the hot and cold spots in the background radiation. The COBE maps have been confirmed and improved by two succeeding space missions, the Wilkinson Microwave Anisotropy Probe (WMAP, built by GSFC with Princeton University), and the Planck mission built by ESA. Based on these maps, astronomers have now developed a "standard model" of cosmology and have

  14. Karl Friedrich Zollner and the historical dimension of astronomical photometry

    Science.gov (United States)

    Sterken, C.; Staubermann, K. B.

    This book results from presentations and discussions of a group of astronomers and historians during a one-day workshop held at Archenhold Observatory, Berlin-Treptow, on April 4, 1997. This meeting was the first forum in a series dedicated to historical aspects of observational astrophysics in the nineteenth and early twentieth century. The basic principle of these meetings is to reflect during one or more days on the work and personality of a single individual or of a group of persons, at the same time avoiding the really dominant figures that typify the age. By focusing on key people who epitomize a way of thinking and working that has formed many of the ideas by which we do astrophysical research today, we also attempt to evoke the scientific spirit of the era under consideration. In 1858, the German physicist Karl Friedrich Zoellner introduced a new type of astronomical photometer which became a bestseller in the second half of the nineteenth century and which led him to the first German professorship in astrophysics. His type of photometer allowed most accurate photometric measurements and was used at several observatories for almost half a century. This book outlines four major themes. The first part describes the observing instruments that were used by Zoellner and his contemporaries: photometers and spectrographs that complemented his original design, but also competed with his most versatile prototype photometer. The description also includes an account of technical aspects associated with the replication of such a photometer today. The second part analyses the astrophysical data that were obtained with Zoellner's tools, and extracts information hidden in the published data --- scientific information as well as diverse aspects related to the observer himself. These nineteenth-century data are now published for the first time on a modern magnitude scale and are directly accessible in tabular form, and are thus fully applicable to archeophotometric studies

  15. Fluctuations of quasars and other astronomical sources: final report on New Research Initiatives Program W-210

    International Nuclear Information System (INIS)

    Terrell, J.

    1978-01-01

    New Research Initiatives Program W-210 produced a number of scientific results, publications, colloquia, and talks. Investigations under this program dealt with power spectra of fluctuating light sources, the apparent expansion rates of astronomical sources exploding at relativistic speed, the limits on fluctuation rates of such expanding (and nonexpanding) light sources, and related matters. Probably the most important result was a study of the time history of such an exploding light source, which showed that a widely held belief that unusually rapid fluctuations of light output would be produced in this case is not correct. This result has an important bearing on the interpretation of the redshifts of quasars and BL Lac objects, indicating that cosmological distance is very difficult to reconcile with the observations of rapid variations of luminosity. These results, and the power-spectrum results, are also of considerable interest in the study of astronomical x-ray sources. A list of publications is included

  16. European astronomers' successes with the Hubble Space Telescope*

    Science.gov (United States)

    1997-02-01

    can bend the light from more distant objects, so magnifying and intensifying their images. In one spectacular case, cluster Abell 2218 creates in Hubble's WFPC2 camera more than a hundred images of galaxies lying beyond it. Without the magnifying effect of the cluster, many of these remote objects would be too faint to study in detail. Compared with man-made optics, the gravitational lenses are complex. They produce multiple images (as many as seven or more views of the same object) and they also smear the images into arcs. Team-member Jean-Paul Kneib, who is now at Toulouse, uses the distortions as a guide to distance. The more distorted the image, the farther off a galaxy is. The galaxies imaged by Abell 2218 are 5 to 8 billion light-years away, and Kneib's estimates have been confirmed by Tim Ebbels of Cambridge using the William Herschel Telescope located on the Spanish island of La Palma. Seen as they were early in the history of the Universe, the objects seem surprisingly similar to nearer and more mature galaxies. The cosmic scale Gustav Tammann of Basel and his collaborators use the Hubble Space Telescope to measure the Hubble Constant. Both are named after Edwin Hubble who discovered, almost 70 years ago, that the galaxies are spreading apart. The Hubble Constant is the rate of expansion -- and the most important number in cosmology, because it fixes the size and the maximum age of the observable Universe. Since the launch of the space telescope in 1990, two independent teams have tried to fix the constant but their answers disagree. A high expansion rate, which makes the Universe relatively young, is preferred by Wendy Freedman's team consisting largely of American astronomers. A lower value for Hubble's Constant, implying an older Universe, comes from a mainly European team led by the American astronomer Allan Sandage. Tammann belongs to the latter, "old Universe" camp and he is philosophical about the delay in reaching a consensus. "I've been waiting

  17. TMT in the Astronomical Landscape of the 2020s

    Science.gov (United States)

    Dickinson, Mark; Inami, Hanae

    2014-07-01

    Thirty Meter Telescope Observatory and NOAO will host the second TMT Science Forum at Loews Ventana Canyon Resort in Tucson, Arizona. The TMT Science Forum is an an annual gathering of astronomers, educators, and observatory staff, who meet to explore TMT science, instrumentation, observatory operations, archiving and data processing, astronomy education, and science, technology, engineering, and math (STEM) issues. It is an opportunity for astronomers from the international TMT partners and from the US-at-large community to learn about the observatory status, discuss and plan cutting-edge science, establish collaborations, and to help shape the future of TMT. One important theme for this year's Forum will be the synergy between TMT and other facilities in the post-2020 astronomical landscape. There will be plenary sessions, an instrumentation workshop, topical science sessions and meetings of the TMT International Science Development Teams (ISDTs).

  18. Stereoscopy in Astronomical Visualizations to Support Learning at Informal Education Settings

    Science.gov (United States)

    Price, Aaron; Lee, Hee-Sun

    2015-08-01

    Stereoscopy has been used in science education for 100 years. Recent innovations in low cost technology as well as trends in the entertainment industry have made stereoscopy popular among educators and audiences alike. However, experimental studies addressing whether stereoscopy actually impacts science learning are limited. Over the last decade, we have conducted a series of quasi-experimental and experimental studies on how children and adult visitors in science museums and planetariums learned about the structure and function of highly spatial scientific objects such as galaxies, supernova, etc. We present a synthesis of the results from these studies and implications for stereoscopic visualization development. The overall finding is that the impact of stereoscopy on perceptions of scientific objects is limited when presented as static imagery. However, when presented as full motion films, a significantly positive impact was detected. To conclude, we present a set of stereoscopic design principles that can help design astronomical stereoscopic films that support deep and effective learning. Our studies cover astronomical content such as the engineering of and imagery from the Mars rovers, artistic stereoscopic imagery of nebulae and a high-resolution stereoscopic film about how astronomers measure and model the structure of our galaxy.

  19. Progress on the New York State Observatory: a new 12-meter astronomical telescope

    Science.gov (United States)

    Sebring, T.; O'Dea, C.; Baum, S.; Teran, J.; Loewen, N.; Stutzki, C.; Egerman, R.; Bonomi, G.

    2014-07-01

    Over the past two years, the New York Astronomical Corporation (NYAC), the business arm of the Astronomical Society of New York (ASNY), has continued planning and technical studies toward construction of a 12-meter class optical telescope for the use of all New York universities and research institutions. Four significant technical studies have been performed investigating design opportunities for the facility, the dome, the telescope optics, and the telescope mount. The studies were funded by NYAC and performed by companies who have provided these subsystems for large astronomical telescopes in the past. In each case, innovative and cost effective approaches were identified, developed, analyzed, and initial cost estimates developed. As a group, the studies show promise that this telescope could be built at historically low prices. As the project continues forward, NYAC intends to broaden the collaboration, pursue funding, to continue to develop the telescope and instrument designs, and to further define the scientific mission. The vision of a historically large telescope dedicated to all New York institutions continues to grow and find new adherents.

  20. Possible astronomical references in two megalithic building of ancient Latium

    Science.gov (United States)

    Magli, G.

    In the wide area of the ancient Latium Vetus - roughly enclosed within the coast and the Apennines between Rome and Terracina, in Central Italy - there are several examples of town's walls and buildings constructed with the spectacular megalithic technique called polygonal, in which enormous blocks are cut in irregular shapes and perfectly fit together without mortar. In many cases, for instance in Alatri, Arpino, Circei, Norba and Segni, the megalithic size of the blocks and the ingenuity in construction reach the same magnificence and impression of power and pride which characterize the worldwide famous Mycenaean towns of Tiryns and Mycenae, constructed around the XIII century BC. In Italy however, all polygonal walls are currently attributed to the Romans, and dated to the first centuries of the Roman republic (V-III century BC), although for most of these constructions no reliable stratigraphy is available. In the present work, which is part of an ongoing project aiming at a complete study of these buildings, we investigate the possible astronomical references in the planning of two among the most imposing of them, namely the so called Acropolis of Alatri and Circei.

  1. Initiating Young Children into Basic Astronomical Concepts and Phenomena

    Science.gov (United States)

    Kallery, M.

    2010-07-01

    In the present study we developed and implemented three units of activities aiming at acquainting very young children with basic astronomical concepts and phenomena such as the sphericity of the earth, the earth’s movements and the day/night cycle. The activities were developed by a group composed of a researcher/facilitator and six early-years teachers. In the activities children were presented with appropriate for their age scientific information along with conceptual tools such as a globe and an instructional video. Action research processes were used to optimize classroom practices and to gather useful information for the final shaping of the activities and the instruction materials. In these activities the adopted approach to learning can be characterized as socially constructed. The results indicated awareness of concepts and phenomena that the activities dealt with in high percentages of children, storage of the new knowledge in the long term memory and easy retrieval of it, and children’s enthusiasm for the subject.

  2. Risk Assessment Integrated QbD Approach for Development of Optimized Bicontinuous Mucoadhesive Limicubes for Oral Delivery of Rosuvastatin.

    Science.gov (United States)

    Javed, Md Noushad; Kohli, Kanchan; Amin, Saima

    2018-04-01

    Statins are widely prescribed for hyperlipidemia, cancer, and Alzheimer's disease but are facing some inherent challenges such as low solubility and drug loading, higher hepatic metabolism, as well as instability at gastric pH. So, relatively higher circulating dose, required for exerting the therapeutic benefits, leads to dose-mediated severe toxicity. Furthermore, due to low biocompatibility, high toxicity, and other regulatory caveats such as product conformity, reproducibility, and stability of conventional formulations as well as preferentially higher bioabsorption of lipids in their favorable cuboidal geometry, enhancement in in vivo biopharmaceutical performance of Rosuvastatin could be well manifested in Quality by Design (QbD) integrated cuboidal-shaped mucoadhesive microcrystalline delivery systems (Limicubes). Here, quality-target-product-profile (QTPPs), critical quality attributes (CQAs), Ishikawa fishbone diagram, and integration of risk management through risk assessment matrix for failure mode and effects analysis (FMEA) followed by processing of Plackett-Burman design matrix using different statistical test for the first time established an approach to substantiate the claims that controlling levels of only these three screened out independent process variables, i.e., Monoolein (B = 800-1100 μL), Poloxamer (C = 150-200 mg), and stirring speed (F = 700-1000 rpm) were statistically significant to modulate and improve the biopharmaceutical performance affecting key attributes, viz., average particle size (Y 1  = 1.40-2.70 μ), entrapment efficiency (Y 2  = 62.60-88.80%), and drug loading (Y 3  = 0.817-1.15%), in QbD-enabled process. The optimal performance of developed Limicubes exhibited an average particle size of 1.8 ± 0.2 μ, entrapment efficiency 80.32 ± 2.88%, and drug loading 0.93 ± 0.08% at the level of 1100 μL (+ 1), 200 mg (+ 1), and 700 rpm (- 1) for Monoolein, Poloxamer, and stirring

  3. Astroinformatics, data mining and the future of astronomical research

    Energy Technology Data Exchange (ETDEWEB)

    Brescia, Massimo, E-mail: longo@na.infn.it [INAF, Astronomical Obs. of Capodimonte, Via Moiariello 16, I-80131 Napoli (Italy); Longo, Giuseppe [Department of Physics, University Federico II, Via Cintia 6, 80126 Napoli (Italy); Department of Astronomy, Caltech, Pasadena (United States)

    2013-08-21

    Astronomy, as many other scientific disciplines, is facing a true data deluge which is bound to change both the praxis and the methodology of every day research work. The emerging field of astroinformatics, while on the one end appears crucial to face the technological challenges, on the other is opening new exciting perspectives for new astronomical discoveries through the implementation of advanced data mining procedures. The complexity of astronomical data and the variety of scientific problems, however, call for innovative algorithms and methods as well as for an extreme usage of ICT technologies.

  4. Dante, astrología y astronomía

    OpenAIRE

    Gangui, Alejandro

    2017-01-01

    En este artículo, los versos de Dante Alighieri nos llevan a reflexionar acerca de los diferentes métodos -cada vez más divergentes- con los que la ciencia y las creencias se aproximan a la realidad. Fil: Gangui, Alejandro. Consejo Nacional de Investigaciónes Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Astronomía y Física del Espacio. - Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Astronomía y Físi...

  5. Astroinformatics, data mining and the future of astronomical research

    International Nuclear Information System (INIS)

    Brescia, Massimo; Longo, Giuseppe

    2013-01-01

    Astronomy, as many other scientific disciplines, is facing a true data deluge which is bound to change both the praxis and the methodology of every day research work. The emerging field of astroinformatics, while on the one end appears crucial to face the technological challenges, on the other is opening new exciting perspectives for new astronomical discoveries through the implementation of advanced data mining procedures. The complexity of astronomical data and the variety of scientific problems, however, call for innovative algorithms and methods as well as for an extreme usage of ICT technologies

  6. A new astronomical dating of Odysseus return to Ithaca.

    Science.gov (United States)

    Papamarinopoulos, St. P.; Preka-Papadema, P.; Antonopoulos, P.; Mitropetrou, H.; Tsironi, A.; Mitropetros, P.

    The annular solar eclipse, of 30 October 1207 B.C. (Julian Day-JD 1280869), calculated by NASA together with the analysis of the weather's and the environment's description (long nights, plants, animals and peoples' habits) and the astronomical data (guiding constellations and Venus in the east horizon) mentioned by Homer in the epic, constitute an autumn return of Odysseus to Ithaca five days before the above characterized day. The latter offers a precise astronomical dating of the event and dates the legendary Trojan War's end as well.

  7. The Moon in Close-up A Next Generation Astronomer's Guide

    CERN Document Server

    Wilkinson, John

    2010-01-01

    Information collected by recent space probes sent to explore the Moon by the USA, the European Space Agency, Japan, China and India has changed our knowledge and understanding of the Moon, particularly its geology, since the Apollo missions. This book presents those findings in a way that will be welcomed by amateur astronomers, students, educators and anyone interested in the Moon. Enhanced by many colour photos, it combines newly acquired scientific understanding with detailed descriptions and labelled photographic maps of the lunar surface. Guided by observation methods explained in the book and 17 Study Areas presented and carefully explained in the last chapter, amateur astronomers can observe these features from Earth using telescopes and binoculars. Readers who consult the photographic maps will gain a better understanding about the Moon’s topography and geology. The book is rounded out by a helpful glossary.

  8. Galactic archaeology for amateur astronomers: RR Lyrae stars as tracers of the Milky Way formation

    Science.gov (United States)

    Carballo-Bello, Julio A.; Martínez-Delgado, David; Fliri, Jürgen

    2011-06-01

    Cosmological models predict that large galaxies like the Milky Way formed from the accretion of smaller stellar systems. The most spectacular of these merger events are stellar tidal streams, rivers of stars and dark matter that envelop the discs of spiral galaxies. We present a research project for a collaboration with amateur astronomers in the study of the formation process of our Galaxy. The main objective is the search for RR Lyrae variable stars in the known stellar streams (Sagitarius, Monoceros, Orphan, etc) a project that can be carried out using small telescopes. The catalogue of candidate variable stars were selected from SDSS data based in colour criteria and it will be sent to interested amateur astronomers who wish to participate in scientific research in one of the most active and competitive topics in Galactic astronomy.

  9. Young Star May Be Belching Spheres of Gas, Astronomers Say

    Science.gov (United States)

    2001-05-01

    National Radio Astronomy Observatory. It consists of ten radio-telescope antennas, each 82 feet (25 meters) in diameter, spread across the U.S. from Hawaii to the U.S. Virgin Islands. Operated from Socorro, New Mexico, the VLBA provides astronomers with the greatest angular resolution, or ability to see fine detail, of any telescope on Earth or in space. The National Radio Astronomy Observatory is a facility of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc. The Center for Astrophysics combines the resources and research facilities of the Harvard College Observatory and the Smithsonian Astrophysical Observatory under a single director to pursue studies of those basic physical processes that determine the nature and evolution of the universe. Some 300 Smithsonian and Harvard scientists cooperate in broad programs of astrophysical research supported by Federal appropriations and University funds as well as contracts and grants from government agencies.

  10. Categorization of alternative astronomical and scientifical conceptions of the teachers from the north coast of São Paulo

    Science.gov (United States)

    Gonzaga, E. P.

    2016-05-01

    This work deals with the analysis of scientific and alternative astronomical concepts found in the responses of teachers who teach classes Science, Geography and Physic in Basic Education (BE) of the state of the North Coast of São Paulo and how to address the alternative astronomical concepts with students from students Fundamental Education (FE) and Medium Education (ME). Bringing the legal documents regarding the Astronomy in BE, within the national and the São Paulo regions curriculum level, also with rationed researches to the teacher's formation, conceptual errors in books, knowledge non-formal spaces, alternative concepts, Astronomical studies and content analysis for fundamental theoretical. The task executed with the teachers was done via Technical Orientations (TO), promoted by the Director of Education (DE) from Caraguatatuba and region, with the premise to threat the continuous formation giving moments of discussion, practical activities and using the Digital Mobile Planetarium (DMP) with non-formal spaces of knowledge to the Astronomical studies gathering data via questions. Within the analysis of the answers analysis by the teachers, tables were created with the categories that highlight actual situations on the astronomical studies in the North Coast of São Paulo, and demarked the possible paths where the continuous formation will be followed in the future. Aspects checked in the survey were highlighted; such as teachers understand that they need continuing education; teachers have scientific astronomical views on various aspects know to teach concepts of Astronomy at BE; TO is a viable option as continued training and the use of DMP as no formal teaching and learning.

  11. Fastest Pulsar Speeding Out of Galaxy, Astronomers Discover

    Science.gov (United States)

    2005-08-01

    A speeding, superdense neutron star somehow got a powerful "kick" that is propelling it completely out of our Milky Way Galaxy into the cold vastness of intergalactic space. Its discovery is puzzling astronomers who used the National Science Foundation's Very Long Baseline Array (VLBA) radio telescope to directly measure the fastest speed yet found in a neutron star. Pulsar's Path Across Sky Over about 2.5 million years, Pulsar B1508+55 has moved across about a third of the night sky as seen from Earth. CREDIT: Bill Saxton, NRAO/AUI/NSF (Click on image for larger version 67 KB) The neutron star is the remnant of a massive star born in the constellation Cygnus that exploded about two and a half million years ago in a titanic explosion known as a supernova. Ultra-precise VLBA measurements of its distance and motion show that it is on course to inevitably leave our Galaxy. "We know that supernova explosions can give a kick to the resulting neutron star, but the tremendous speed of this object pushes the limits of our current understanding," said Shami Chatterjee, of the National Radio Astronomy Observatory (NRAO) and the Harvard-Smithsonian Center for Astrophysics. "This discovery is very difficult for the latest models of supernova core collapse to explain," he added. Chatterjee and his colleagues used the VLBA to study the pulsar B1508+55, about 7700 light-years from Earth. With the ultrasharp radio "vision" of the continent-wide VLBA, they were able to precisely measure both the distance and the speed of the pulsar, a spinning neutron star emitting powerful beams of radio waves. Plotting its motion backward pointed to a birthplace among groups of giant stars in the constellation Cygnus -- stars so massive that they inevitably explode as supernovae. "This is the first direct measurement of a neutron star's speed that exceeds 1,000 kilometers per second," said Walter Brisken, an NRAO astronomer. "Most earlier estimates of neutron-star speeds depended on educated

  12. On the Astronomical Knowledge and Traditions of Aboriginal Australians

    Science.gov (United States)

    Hamacher, Duane W.

    2011-12-01

    Historian of science David Pingree defines science in a broad context as the process of systematically explaining perceived or imaginary phenomena. Although Westerners tend to think of science being restricted to Western culture, I argue in this thesis that astronomical scientific knowledge is found in Aboriginal traditions. Although research into the astronomical traditions of Aboriginal Australians stretches back for more than 150 years, it is relatively scant in the literature. We do know that the sun, moon, and night sky have been an important and inseparable component of the landscape to hundreds of Australian Aboriginal groups for thousands (perhaps tens-of-thousands) of years. The literature reveals that astronomical knowledge was used for time keeping, denoting seasonal change and the availability of food sources, navigation, and tidal prediction. It was also important for rituals and ceremonies, birth totems, marriage systems, cultural mnemonics, and folklore. Despite this, the field remains relatively unresearched considering the diversity of Aboriginal cultures and the length of time people have inhabited Australia (well over 40,000 years). Additionally, very little research investigating the nature and role of transient celestial phenomena has been conducted, leaving our understanding of Indigenous astronomical knowledge grossly incomplete. This thesis is an attempt to overcome this deficiency, with a specific focus on transient celestial phenomena. My research, situated in the field of cultural astronomy, draws from the sub-disciplines of archaeoastronomy, ethnoastronomy, historical astronomy, and geomythology. This approach incorporates the methodologies and theories of disciplines in the natural sciences, social sciences, and humanities. This thesis, by publication, makes use of archaeological, ethnographic, and historical records, astronomical software packages, and geographic programs to better understand the ages of astronomical traditions and the

  13. Long scale astronomical variations in our solar system: consequences for future ice ages

    International Nuclear Information System (INIS)

    Edvardsson, S.; Karlsson, K.G.

    2002-01-01

    It is well known that the Earth has gone through a number of glaciations during the last few million years. It is generally agreed that changes in the Earth's orbital parameters and obliquity play an important role in climate forcing, an idea originally due to Milutin Milankovitch. The climatic history of the Earth shows clear evidence of the precession periods (about 19 000 and 23 000 years) and changes in the obliquity (period about 41 000 years). The main period in glacial data (around 100 000 years) is, however, hard to explain in terms of orbital variations. During the last decade or so a large number of simulations of the planetary system have been reported, many of which have been concerned with the influence of variations in the Earth's orbit on climate. In former studies comparisons have been made between the astronomical parameters and the ice volume of the Earth. Generally speaking, the match between astronomical forcing and ice data has been rather poor. In this study we instead compare the parameters with changes in ice volume, which yields a much better agreement between the astronomical and the geological data. A number of climate models have been constructed to reproduce past climate history, and also to make predictions about the future. These are purely empirical models designed to match certain periods of past climate. Typically they also involve a substantial number of free parameters. (authors)

  14. Communicating the Science of Global Warming — the Role of Astronomers

    Science.gov (United States)

    Bennett, Jeffrey

    2018-06-01

    Global Warming is one of the most important and issues of our times, yet it is widely misunderstood among the general public (and politicians!). The American Astronomical Society has already joined many other scientific organizations in advocating for action on global warming (by supporting the AGU statement on global warming), but we as astronomers can do much more. The high public profile of astronomy gives us a unique platform — and credibility as scientists — for doing our part to educate the public about the underlying science of global warming. And while astronomers are not climate scientists, we use the same basic physics, and many aspects of global warming science come directly from astronomy, including the ways in which we measure the heat-absorbing potential of carbon dioxide and the hard evidence of greenhouse warming provided by studies of Venus. In this session, I will briefly introduce a few methods for communicating about global warming that I believe you will find effective in your own education efforts.

  15. A Virtual Astronomical Research Machine in No Time (VARMiNT)

    Science.gov (United States)

    Beaver, John

    2012-05-01

    We present early results of using virtual machine software to help make astronomical research computing accessible to a wider range of individuals. Our Virtual Astronomical Research Machine in No Time (VARMiNT) is an Ubuntu Linux virtual machine with free, open-source software already installed and configured (and in many cases documented). The purpose of VARMiNT is to provide a ready-to-go astronomical research computing environment that can be freely shared between researchers, or between amateur and professional, teacher and student, etc., and to circumvent the often-difficult task of configuring a suitable computing environment from scratch. Thus we hope that VARMiNT will make it easier for individuals to engage in research computing even if they have no ready access to the facilities of a research institution. We describe our current version of VARMiNT and some of the ways it is being used at the University of Wisconsin - Fox Valley, a two-year teaching campus of the University of Wisconsin System, as a means to enhance student independent study research projects and to facilitate collaborations with researchers at other locations. We also outline some future plans and prospects.

  16. How did the Supreme Court ruling on DOMA affect astronomers?

    Science.gov (United States)

    Rigby, Jane R.; The AAS Working Group on LGBTIQ Equality

    2014-01-01

    In June 2013, the United States Supreme Court ruled that Section 3 of the Defense of Marriage Act (DOMA) was unconstitutional. Section 3 had barred the federal government from recognizing same-sex marriages. The decision in United States v. Windsor, made headlines around the world, and particularly affected astronomers, since astronomers in the US are more likely than the general population to be foreign nationals, to have a foreign-born spouse, or to work for the federal government. In this poster, we highlight some of the real-world ways that the Windsor case has affected US astronomers and our profession. Bi-national couples can now apply for green cards granting permanent residency. Scientists who work for the federal government, including NASA and the NSF, can now obtain health insurance for a same-sex spouse. From taxes to death benefits, health insurance to daycare, immigration to ethics laws, the end of S3 of DOMA has had profoundly improved the lives of US scientists who are lesbian, gay, bisexual, or transgender (LGBT). Here we, highlight several real-world examples of how DOMA's demise has improved the lives and careers of US astronomer.

  17. The High Road to Astronomical Photometric Precision : Differential Photometry

    NARCIS (Netherlands)

    Milone, E. F.; Pel, Jan Willem

    2011-01-01

    Differential photometry offers the most precise method for measuring the brightness of astronomical objects. We attempt to demonstrate why this should be the case, and then describe how well it has been done through a review of the application of differential techniques from the earliest visual

  18. Astronomy for Astronomical Numbers: A Worldwide Massive Open Online Class

    Science.gov (United States)

    Impey, Chris D.; Wenger, Matthew C.; Austin, Carmen L.

    2015-01-01

    Astronomy: State of the Art is a massive, open, online class (MOOC) offered through Udemy by an instructional team at the University of Arizona. With nearly 24,000 enrolled as of early 2015, it is the largest astronomy MOOC available. The astronomical numbers enrolled do not translate into a similar level of engagement. The content consists of 14…

  19. Recent Advances for LGBT Astronomers in the United States

    Science.gov (United States)

    Dixon, William V.; Rigby, Jane; Oppenheimer, Rebecca

    2015-08-01

    The legal environment for lesbian, gay, bisexual, and transgender (LGBT) astronomers in the United States has changed dramatically in recent years. In 2013, the Supreme Court ruled that Section 3 of the Defense of Marriage Act (DOMA), which had barred the federal government from recognizing same-sex marriages, was unconstitutional. This decision particularly affects astronomers, since astronomers in the U.S. are more likely than the general population to be foreign nationals, to have a foreign-born spouse, or to work for the federal government. In 2014, the Attorney General directed the Department of Justice to take the position in litigation that the protection of Title VII of the Civil Rights Act of 1964 extends to claims of discrimination based on an individual’s gender identity, including transgender status. Title VII makes it unlawful for employers to discriminate in the employment of an individual “because of such individual’s... sex,” among other protected characteristics. As of March 2015, more than 70% of the population lives in states that recognize same-sex marriage, and the Supreme Court is expected to rule on the constitutionality of the remaining same-sex marriage bans during the current term. In this poster, we discuss these advances and their implications for the personal and professional lives of LGBT astronomers across the United States.

  20. Instrument Remote Control via the Astronomical Instrument Markup Language

    Science.gov (United States)

    Sall, Ken; Ames, Troy; Warsaw, Craig; Koons, Lisa; Shafer, Richard

    1998-01-01

    The Instrument Remote Control (IRC) project ongoing at NASA's Goddard Space Flight Center's (GSFC) Information Systems Center (ISC) supports NASA's mission by defining an adaptive intranet-based framework that provides robust interactive and distributed control and monitoring of remote instruments. An astronomical IRC architecture that combines the platform-independent processing capabilities of Java with the power of Extensible Markup Language (XML) to express hierarchical data in an equally platform-independent, as well as human readable manner, has been developed. This architecture is implemented using a variety of XML support tools and Application Programming Interfaces (API) written in Java. IRC will enable trusted astronomers from around the world to easily access infrared instruments (e.g., telescopes, cameras, and spectrometers) located in remote, inhospitable environments, such as the South Pole, a high Chilean mountaintop, or an airborne observatory aboard a Boeing 747. Using IRC's frameworks, an astronomer or other scientist can easily define the type of onboard instrument, control the instrument remotely, and return monitoring data all through the intranet. The Astronomical Instrument Markup Language (AIML) is the first implementation of the more general Instrument Markup Language (IML). The key aspects of our approach to instrument description and control applies to many domains, from medical instruments to machine assembly lines. The concepts behind AIML apply equally well to the description and control of instruments in general. IRC enables us to apply our techniques to several instruments, preferably from different observatories.

  1. Paired and Interacting Galaxies: International Astronomical Union Colloquium No. 124

    Science.gov (United States)

    Sulentic, Jack W. (Editor); Keel, William C. (Editor); Telesco, C. M. (Editor)

    1990-01-01

    The proceedings of the International Astronomical Union Colloquium No. 124, held at the University of Alabama at Tuscaloosa, on December 4 to 7, are given. The purpose of the conference was to describe the current state of theoretical and observational knowledge of interacting galaxies, with particular emphasis on galaxies in pairs.

  2. Radio Recombination Lines Their Physics and Astronomical Applications

    CERN Document Server

    Gordon, MA

    2008-01-01

    Includes the history of RRL detections, the astrophysics underlying their intensities and line shapes including topics like departures from LTE and Stark broadening, the maximum possible size of an atom, and descriptions of the astronomical topics for which RRLs have proved to be effective tools.

  3. Radio astronomical interferometry and x-ray's computerized tomography

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez, L F [Universidad Nacional Autonoma de Mexico, Mexico City. Inst. de Astronomia

    1982-01-01

    Radio astronomical interferometry and computerized tomography are techniques of great importance for astronomy and medicine, respectively. In this paper we emphasize that both techniques are based on the same mathematical principles, and present them as an example of interaction between basic and applied science.

  4. Infrared Astronomical Satellite (IRAS) Catalogs and Atlases. Explanatory Supplement

    Science.gov (United States)

    Beichman, C. A. (Editor); Neugebauer, G. (Editor); Habing, H. J. (Editor); Clegg, P. E. (Editor); Chester, T. J. (Editor)

    1985-01-01

    The Infrared Astronomical Satellite (IRAS) mission is described. An overview of the mission, a description of the satellite and its telescope system, and a discussion of the mission design, requirements, and inflight modifications are given. Data reduction, flight tests, flux reconstruction and calibration, data processing, and the formats of the IRAS catalogs and atlases are also considered.

  5. Circulating N-Linked Glycoprotein Side-Chain Biomarker, Rosuvastatin Therapy, and Incident Cardiovascular Disease: An Analysis From the JUPITER Trial.

    Science.gov (United States)

    Akinkuolie, Akintunde O; Glynn, Robert J; Padmanabhan, Latha; Ridker, Paul M; Mora, Samia

    2016-07-13

    GlycA, a novel protein glycan biomarker of N-acetyl side chains of acute-phase proteins, was recently associated with incident cardiovascular disease (CVD) in healthy women. Whether GlycA predicts CVD events in the setting of statin therapy in men and women without CVD but with evidence of chronic inflammation is unknown. In the Justfication for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial (NCT00239681), participants with low-density lipoprotein cholesterol 0.20). In the JUPITER trial, increased levels of GlycA were associated with an increased risk of CVD events independent of traditional risk factors and hsCRP. URL: http://www.clinicaltrials.gov. Unique identifier: NCT00239681. © 2016 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

  6. NRAO Astronomer Wins Max-Planck Research Award

    Science.gov (United States)

    2005-04-01

    Dr. Christopher Carilli, a National Radio Astronomy Observatory (NRAO) astronomer in Socorro, New Mexico, has been chosen to receive the prestigious Max Planck Research Award from the Alexander von Humboldt Foundation and the Max Planck Society in Germany. Christopher Carilli Dr. Christopher Carilli Click on image for more photos CREDIT: NRAO/AUI/NSF Carilli, a radio astronomer, and German particle physicist Christof Wetterich are the 2005 recipients of the award, conferred on "one researcher working in Germany and one working abroad who have already gained an international reputation and who are expected to produce outstanding achievements in the framework of international collaboration," according to an announcement from the Humboldt Foundation. "This is a great honor for Chris, and we are proud to see him receive such important international recognition for the excellence of his research," said NRAO Director Fred K.Y. Lo. Carilli's research has focused on studying very distant galaxies in the early Universe, and a quest to find the first luminous objects, such as stars or galaxies, to emerge. His most recent interests focus on unveiling the mysteries of what cosmologists call the "Epoch of Reionization," when the first stars and galaxies ionized the neutral hydrogen that pervaded the young Universe. Carilli and his research colleagues have used NRAO's Very Large Array and other radio telescopes to discover that the molecular raw material for star formation already was present in a galaxy seen as it was about 800 million years after the Big Bang, less than 1/16 the current age of the Universe. The Max Planck Research Award provides 750,000 Euros (currently about $900,000), to be used over five years, for research. The funding is provided by the German Ministry of Education and Research. Carilli will use the funding to support young researchers and to build scientific instrumentation, with a focus on fostering radio studies of cosmic reionization and the first

  7. Catherine Cesarsky - President Elect of the International Astronomical Union (IAU)

    Science.gov (United States)

    2003-07-01

    The General Assembly of the International Astronomical Union (IAU), meeting in Sydney (Australia), has appointed the ESO Director General, Dr. Catherine Cesarsky, as President Elect for a three-year period (2003-2006). The IAU is the world's foremost organisation for astronomy, uniting almost 9000 professional scientists on all continents. The IAU General Assembly also elected Prof. Ron Ekers (Australia) as President (2003 - 2006). Dr. Cesarsky will then become President of the IAU in 2006, when the General Assembly next meets in Prague (The Czech Republic). Dr. Cesarsky is the first woman scientist to receive this high distinction. "The election of Catherine Cesarsky as President-Elect of the IAU is an important recognition for a scientist who has made impressive contributions to various areas of modern astrophysics, from cosmic rays to the interstellar medium and cosmology" , commented the outgoing IAU President, Prof. Franco Pacini. "It is also an honour and an important accolade for the European astronomical community in general and ESO in particular." Dr. Cesarsky, who assumed the function as ESO Director General in 1999, was born in France. She received a degree in Physical Sciences at the University of Buenos Aires and graduated with a PhD in Astronomy in 1971 from Harvard University (Cambridge, Mass., USA). Afterwards she worked at the California Institute of Technology (CALTECH). In 1974, she became a staff member of the Service d'Astrophysique (SAp), Direction des Sciences de la Matière (DSM), Commissariat à l'Energie Atomique (CEA) (France). As Director of DSM (1994 - 1999), she was leading about 3000 scientists, engineers and technicians active within a broad spectrum of basic research programmes in physics, chemistry, astrophysics and earth sciences. Dr. Cesarsky is known for her successful research activities in several central areas of modern astrophysics. She first worked on the theory of cosmic ray propagation and acceleration, and galactic gamma

  8. Brightness Variations of Sun-like Stars: The Mystery Deepens - Astronomers facing Socratic "ignorance"

    Science.gov (United States)

    2009-12-01

    An extensive study made with ESO's Very Large Telescope deepens a long-standing mystery in the study of stars similar to the Sun. Unusual year-long variations in the brightness of about one third of all Sun-like stars during the latter stages of their lives still remain unexplained. Over the past few decades, astronomers have offered many possible explanations, but the new, painstaking observations contradict them all and only deepen the mystery. The search for a suitable interpretation is on. "Astronomers are left in the dark, and for once, we do not enjoy it," says Christine Nicholls from Mount Stromlo Observatory, Australia, lead author of a paper reporting the study. "We have obtained the most comprehensive set of observations to date for this class of Sun-like stars, and they clearly show that all the possible explanations for their unusual behaviour just fail." The mystery investigated by the team dates back to the 1930s and affects about a third of Sun-like stars in our Milky Way and other galaxies. All stars with masses similar to our Sun become, towards the end of their lives, red, cool and extremely large, just before retiring as white dwarfs. Also known as red giants, these elderly stars exhibit very strong periodic variations in their luminosity over timescales up to a couple of years. "Such variations are thought to be caused by what we call 'stellar pulsations'," says Nicholls. "Roughly speaking, the giant star swells and shrinks, becoming brighter and dimmer in a regular pattern. However, one third of these stars show an unexplained additional periodic variation, on even longer timescales - up to five years." In order to find out the origin of this secondary feature, the astronomers monitored 58 stars in our galactic neighbour, the Large Magellanic Cloud, over two and a half years. They acquired spectra using the high resolution FLAMES/GIRAFFE spectrograph on ESO's Very Large Telescope and combined them with images from other telescopes [1

  9. Astronomical cycle origin of bedded chert: A middle Triassic bedded chert sequence, Inuyama, Japan

    Science.gov (United States)

    Ikeda, Masayuki; Tada, Ryuji; Sakuma, Hironobu

    2010-09-01

    Astronomical forcing is one of the main drivers of climate change, and astronomical cyclicity recorded in sediments provides a clue to understand the dynamics of the global climate system. Bedded cherts consist of rhythmic alternations of chert and shale beds. Although previous studies have hypothesized that the origin of bedded chert is related to astronomical cycles (e.g. Fischer, 1976; Hori et al., 1993), conclusive proof remains elusive. To explore this possibility, we established a continuous, high-resolution lithostratigraphy of middle Triassic bedded chert in Central Japan. The average duration of each chert-shale couplet is 20 kyr, similar to that of the precession cycle. Spectral analysis of a bed number series of thickness variations in chert beds was performed assuming that each chert-shale couplet represents a 20-kyr precession cycle. The results reveal cycles involving approximately 200, 20, 5, and 2-3 beds, corresponding to periodicities of approximately 4000, 400, 100, and 40-60 kyr, respectively. By further assuming that the 20-bed cycle represents a 405-kyr eccentricity cycle of constant and stable periodicity, we converted the bed number series to a time series. Spectral analysis of the time series revealed distinct periodicities of 3600, 117, 97, and 38 kyr, in addition to 405 kyr. Besides 3600 kyr, these periodicities agree well with the 120, 95, and 37 kyr periodicities for eccentricity cycles and the obliquity cycle during the Triassic. Moreover, we detected amplitude modulation of the approximately 100-kyr cycle of thickness variations in chert beds with a 405-kyr periodicity, which may correspond to amplitude modulation of 100-kyr climatic precession cycle with the 405-kyr periodicity. The approximately 3600-kyr periodicity described above and 1800-kyr periodicity manifested as the amplitude modulation of the 405-kyr cycle are correlated to present-day long-term eccentricity cycles of 2400 and 4800 kyr evolved by chaotic behavior of solar

  10. This Month in Astronomical History: Providing Context for the Advancement of Astronomy

    Science.gov (United States)

    Wilson, Teresa

    2018-01-01

    This Month in Astronomical History is a short (~500 word) illustrated column hosted on the AAS website (https://had.aas.org/resources/astro-history). Its mission is to highlight people and events that have shaped the development of astronomy to convey a historical context to current researchers, to provide a resource for education and public outreach programs seeking to incorporate a historical perspective, and to share the excitement of astronomy with the public. Knowing how the astronomical journey has proceeded thus far allows current professionals to map where to go next and how to get there. The column charts the first part of this journey by celebrating anniversaries of births, discoveries, and deaths, and the technological advances that made discoveries possible. A new “Further Reading” section encourages readers to pursue subjects in greater depth and strengthens the articles as classroom resources.In the months preceding the 21 August 2017 solar eclipse, the column featured astronomical bodies that come between Earth and the Sun: 2004 Venus transit, the 1878 solar eclipse, and the search for the hypothetical planet Vulcan. Venusian transits were an early but technically challenging way to measure the astronomical unit, now easily done with radar-ranging. Like this year’s event, eclipse chasing and citizen science were part of the 1878 experience. Newton’s Laws seemed to require a planet inside Mercury’s orbit, but General Relativity explained the behavior of Mercury without it. Studying each of these transiting bodies has expanded our knowledge and understanding of the universe differently. Transiting extrasolar planets remain to be explored in a future column. In September, an article on the discovery of Neptune followed the discussion of the non-existent Vulcan quite naturally and expanded on the brief mention of this event in relation to the discovery of Pluto. Suggestions for additional topics are always welcome.The Dudley Observatory

  11. Top astronomers head to the city. Experts to talk on exciting quasar discoveries.

    CERN Multimedia

    Grant, S

    2002-01-01

    The UK National Astronomy Meeting - NAM 2002 - is at Bristol University this week. The meeting is one of the most important regular gatherings of astronomers in the UK. Sponsored by the Royal Astronomical Society and PPARC, it should attract about 300 astronomers from the UK and beyond.

  12. The PACA Project: When Amateur Astronomers Become Citizen Scientists

    Science.gov (United States)

    Yanamandra-Fisher, P. A.

    2014-12-01

    The Pro-Am Collaborative Astronomy (PACA) project evolved from the observational campaign of C/2012 S1 or C/ISON in 2013. Following the success of the professional-amateur astronomer collaboration in scientific research via social media, it is now implemented in other comet observing campaigns. While PACA identifies a consistent collaborative approach to pro-am collaborations, given the volume of data generated for each campaign, new ways of rapid data analysis, mining access and storage are needed. Several interesting results emerged from the synergistic inclusion of both social media and amateur astronomers: (1) the establishment of a network of astronomers and related professionals, that can be galvanized into action on short notice to support observing campaigns; (2) assist in various science investigations pertinent to the campaign; (3) provide an alert-sounding mechanism should the need arise; (4) immediate outreach and dissemination of results via our media/blogger members; (5) provide a forum for discussions between the imagers and modelers to help strategize the observing campaign for maximum benefit. In 2014, two new comet observing campaigns involving pro-am collaborations have been initiated: (1) C/2013 A1 (C/SidingSpring) and (2) 67P/Churyumov-Gerasimenko (CG), target for ESA/Rosetta mission. The evolving need for individual customized observing campaigns has been incorporated into the evolution of PACA portal that currently is focused on comets: from supporting observing campaigns of current comets, legacy data, historical comets; interconnected with social media and a set of shareable documents addressing observational strategies; consistent standards for data; data access, use, and storage, to align with the needs of professional observers. The integration of science, observations by professional and amateur astronomers, and various social media provides a dynamic and evolving collaborative partnership between professional and amateur astronomers

  13. A randomized trial of rosuvastatin in the prevention of venous thromboembolism

    DEFF Research Database (Denmark)

    Glynn, Robert J; Danielson, Eleanor; Fonseca, Francisco A H

    2009-01-01

    BACKGROUND: Controversy persists regarding the extent of shared pathways between arterial and venous thrombosis and whether treatments of known efficacy for one disease process have consistent benefits for the other. Observational studies have yielded variable estimates of the effect of statin...... therapy on the risk of venous thromboembolism, and evidence from randomized trials is lacking. METHODS: We randomly assigned 17,802 apparently healthy men and women with both low-density lipoprotein (LDL) cholesterol levels of less than 130 mg per deciliter (3.4 mmol per liter) and high-sensitivity C...

  14. Scale Marking Method on the Circumference of Circle Elements for Astronomical Instruments in the Early Joseon Dynasty

    Science.gov (United States)

    Mihn, Byeong-Hee; Lee, Ki-Won; Ahn, Young Sook; Lee, Yong Sam

    2015-03-01

    During the reign of King Sejong (世宗, 1418-1450) in the Joseon Dynasty, there were lots of astronomical instruments, including miniaturized ones. Those instruments utilized the technical know-how acquired through building contemporary astronomical instruments previously developed in the Song(宋), Jin(金), and Yuan(元) dynasties of China. In those days, many astronomical instruments had circles, rings, and spheres carved with a scale of 365.25, 100, and 24 parts, respectively, on their circumference. These were called the celestial-circumference degree, hundred-interval (Baekgak), and 24 direction, respectively. These scales are marked by the angular distance, not by the angle. Therefore, these circles, rings, and spheres had to be optimized in size to accomodate proper scales. Assuming that the scale system is composed of integer multiples of unit length, we studied the sizes of circles by referring to old articles and investigating existing artifacts. We discovered that the star chart of Cheonsang yeolcha bunyajido was drawn with a royal standard ruler (周尺) based on the unit length of 207 mm. Interestingly, its circumference was marked by the unit scale of 3 puns per 1 du (or degree) like Honsang (a celestial globe). We also found that Hyeonju ilgu (a equatorial sundial) has a Baekgak disk on a scale of 1 pun per 1 gak (that is an interval of time similar to a quarter). This study contributes to the analysis of specifications of numerous circular elements from old Korean astronomical instruments.

  15. Astronomical virtual observatory and the place and role of Bulgarian one

    Science.gov (United States)

    Petrov, Georgi; Dechev, Momchil; Slavcheva-Mihova, Luba; Duchlev, Peter; Mihov, Bojko; Kochev, Valentin; Bachev, Rumen

    2009-07-01

    Virtual observatory could be defined as a collection of integrated astronomical data archives and software tools that utilize computer networks to create an environment in which research can be conducted. Several countries have initiated national virtual observatory programs that combine existing databases from ground-based and orbiting observatories, scientific facility especially equipped to detect and record naturally occurring scientific phenomena. As a result, data from all the world's major observatories will be available to all users and to the public. This is significant not only because of the immense volume of astronomical data but also because the data on stars and galaxies has been compiled from observations in a variety of wavelengths-optical, radio, infrared, gamma ray, X-ray and more. In a virtual observatory environment, all of this data is integrated so that it can be synthesized and used in a given study. During the autumn of the 2001 (26.09.2001) six organizations from Europe put the establishment of the Astronomical Virtual Observatory (AVO)-ESO, ESA, Astrogrid, CDS, CNRS, Jodrell Bank (Dolensky et al., 2003). Its aims have been outlined as follows: - To provide comparative analysis of large sets of multiwavelength data; - To reuse data collected by a single source; - To provide uniform access to data; - To make data available to less-advantaged communities; - To be an educational tool. The Virtual observatory includes: - Tools that make it easy to locate and retrieve data from catalogues, archives, and databases worldwide; - Tools for data analysis, simulation, and visualization; - Tools to compare observations with results obtained from models, simulations and theory; - Interoperability: services that can be used regardless of the clients computing platform, operating system and software capabilities; - Access to data in near real-time, archived data and historical data; - Additional information - documentation, user-guides, reports

  16. Astrophysics is easy! an introduction for the amateur astronomer

    CERN Document Server

    Inglis, Mike

    2007-01-01

    With some justification, many amateur astronomers believe astrophysics is a very difficult subject, requiring at least degree-level mathematics to understand it properly. This isn’t necessarily the case. Mike Inglis' quantitative approach to the subject explains all aspects of astrophysics in simple terms and cuts through the incomprehensible mathematics with which this fascinating subject is all too often associated. Astrophysics is Easy! begins by looking at the H-R diagram and other basic tools of astrophysics, then ranges across the universe, from a first look at the interstellar medium and nebulae, through the birth, evolution and death of stars, to the physics of galaxies and clusters of galaxies. A unique feature of this book is the way that Dr. Inglis lists example objects for practical observation at every stage, so that practical astronomers can go and look at the object or objects under discussion – using only easily-available commercial amateur equipment.

  17. Alexander the Great's Tomb at Siwa: The Astronomical Orientation

    Science.gov (United States)

    Papathanassiou, M.; Souvaltzis, Em.; Souvaltzi, L.; Moussas, X.

    A preliminary report on the possible astronomical orientation of the Tomb of Alexander the Great, recently found and excavated by the greek archaeologist Liana Souvaltzi. The tomb is a greek building of doric style. Its enormous dimensions make it the largest amongst the found macedonian tombs (much bigger than the tomb of Philip II, Alexander's father). The tomb faces generally south---west and its orientation could be related either to the constellation of Centaurus or to the star Canopus. The walls of the two long sides of the building have strickingly different widhts. Moreover each wall has three doors (opposite in pairs) of slightly different sizes. We examine the possibility the openings of the doors and their assymetries to be designed and constructed according to some astronomical (solar or stellar) orientations.

  18. Using Modern Technologies to Capture and Share Indigenous Astronomical Knowledge

    Science.gov (United States)

    Nakata, Martin; Hamacher, Duane W.; Warren, John; Byrne, Alex; Pagnucco, Maurice; Harley, Ross; Venugopal, Srikumar; Thorpe, Kirsten; Neville, Richard; Bolt, Reuben

    2014-06-01

    Indigenous Knowledge is important for Indigenous communities across the globe and for the advancement of our general scientific knowledge. In particular, Indigenous astronomical knowledge integrates many aspects of Indigenous Knowledge, including seasonal calendars, navigation, food economics, law, ceremony, and social structure. Capturing, managing, and disseminating this knowledge in the digital environment poses a number of challenges, which we aim to address using a collaborative project emerging between experts in the higher education, library, archive and industry sectors. Using Microsoft's WorldWide Telescope and Rich Interactive Narratives technologies, we propose to develop software, media design, and archival management solutions to allow Indigenous communities to share their astronomical knowledge with the world on their terms and in a culturally sensitive manner.

  19. Astronomically speaking a dictionary of quotations on astronomy and physics

    CERN Document Server

    Gaither, CC

    2003-01-01

    To understand the history, accomplishments, failures, and meanings of astronomy requires a knowledge of what has been said about astronomy by philosophers, novelists, playwrights, poets, scientists, and laymen. With this in mind, Astronomically Speaking: A Dictionary of Quotations on Astronomy and Physics serves as a guide to what has been said about astronomy through the ages. Containing approximately 1,550 quotations and numerous illustrations, this resource is the largest compilation of astronomy and astrophysics quotations published to date.Devoted to astronomy and the closely related areas of mathematics and physics, this resource helps form an accurate picture of these interconnected disciplines. It is designed as an aid for general readers with little knowledge of astronomy who are interested in astronomical topics. Students can use the book to increase their understanding of the complexity and richness that exists in scientific disciplines. In addition, experienced scientists will find it as a handy s...

  20. Astronomical Instrumentation Systems Quality Management Planning: AISQMP (Abstract)

    Science.gov (United States)

    Goldbaum, J.

    2017-12-01

    (Abstract only) The capability of small aperture astronomical instrumentation systems (AIS) to make meaningful scientific contributions has never been better. The purpose of AIS quality management planning (AISQMP) is to ensure the quality of these contributions such that they are both valid and reliable. The first step involved with AISQMP is to specify objective quality measures not just for the AIS final product, but also for the instrumentation used in its production. The next step is to set up a process to track these measures and control for any unwanted variation. The final step is continual effort applied to reducing variation and obtaining measured values near optimal theoretical performance. This paper provides an overview of AISQMP while focusing on objective quality measures applied to astronomical imaging systems.

  1. Eighth Scientific Meeting of the Spanish Astronomical Society

    CERN Document Server

    Diego, Jose M; González-Serrano, J. Ignacio; Gorgas, Javier; Highlights of Spanish Astrophysics V

    2010-01-01

    This volume collects the invited contributions and plenary sessions presented at the Eighth Scientific Meeting of the Spanish Astronomical Society (Sociedad Española de Astronomía, SEA) held on July 7-11, 2008 in Santander. These contributions cover all fields of astronomy and astrophysics, i.e., the Sun and solar system, the galaxy and its components, galaxies and cosmology, observatories and instrumentation, as well as astronomy teaching and dissemination. Further plenary sessions were devoted to selected hot topics, including the exploration of the solar system, gravitational lensing, exoplanets, X-ray binaries, solar magnetism, gravitational waves, the ALHAMBRA collaboration, and the OSIRIS instrument on the new 10-m GTC. Abstracts of the contributions presented at the parallels sessions and posters are also included in the book. Complete versions of those papers are available online.

  2. Visualization of Multi-mission Astronomical Data with ESASky

    Science.gov (United States)

    Baines, Deborah; Giordano, Fabrizio; Racero, Elena; Salgado, Jesús; López Martí, Belén; Merín, Bruno; Sarmiento, María-Henar; Gutiérrez, Raúl; Ortiz de Landaluce, Iñaki; León, Ignacio; de Teodoro, Pilar; González, Juan; Nieto, Sara; Segovia, Juan Carlos; Pollock, Andy; Rosa, Michael; Arviset, Christophe; Lennon, Daniel; O'Mullane, William; de Marchi, Guido

    2017-02-01

    ESASky is a science-driven discovery portal to explore the multi-wavelength sky and visualize and access multiple astronomical archive holdings. The tool is a web application that requires no prior knowledge of any of the missions involved and gives users world-wide simplified access to the highest-level science data products from multiple astronomical space-based astronomy missions plus a number of ESA source catalogs. The first public release of ESASky features interfaces for the visualization of the sky in multiple wavelengths, the visualization of query results summaries, and the visualization of observations and catalog sources for single and multiple targets. This paper describes these features within ESASky, developed to address use cases from the scientific community. The decisions regarding the visualization of large amounts of data and the technologies used were made to maximize the responsiveness of the application and to keep the tool as useful and intuitive as possible.

  3. C++, objected-oriented programming, and astronomical data models

    Science.gov (United States)

    Farris, A.

    1992-01-01

    Contemporary astronomy is characterized by increasingly complex instruments and observational techniques, higher data collection rates, and large data archives, placing severe stress on software analysis systems. The object-oriented paradigm represents a significant new approach to software design and implementation that holds great promise for dealing with this increased complexity. The basic concepts of this approach will be characterized in contrast to more traditional procedure-oriented approaches. The fundamental features of objected-oriented programming will be discussed from a C++ programming language perspective, using examples familiar to astronomers. This discussion will focus on objects, classes and their relevance to the data type system; the principle of information hiding; and the use of inheritance to implement generalization/specialization relationships. Drawing on the object-oriented approach, features of a new database model to support astronomical data analysis will be presented.

  4. The Panchasiddhhantika : The Astronomical Work of Varaha Mihira

    Science.gov (United States)

    Thibaut, G.; Dvivedi, Mahamahopadhyaya Sudhakara

    The lamentable state of the text as appearing in the two original manuscripts (of Varah Mihira) at the disposal of the authors, was a lesser problem then the greater disadvantage under which they laboured with the absence of a commentary. Commentaries can be hardly done without in the case of any Sanskrit astronomical work; much less so, when the text, as that of the Panchasiddhantika, describes many mathematical processes more or less diverging from those commonly employed.

  5. The Organization and Management of the Virtual Astronomical Observatory

    Science.gov (United States)

    Berriman, G. Bruce; Hanisch, Robert J.; Lazio, T. Joseph W.; Szalay, Alexander; Fabbiano, Giussepina

    2012-01-01

    The U.S. Virtual Astronomical Observatory (VAO; http://www.us-vao.org/) has been in operation since May 2010. Its goal is to enable new science through efficient integration of distributed multi-wavelength data. This paper describes the management and organization of the VAO, and emphasizes the techniques used to ensure efficiency in a distributed organization. Management methods include using an annual program plan as the basis for establishing contracts with member organizations, regular communication, and monitoring of processes.

  6. The Astronomical Orientation of the Urban Plan of Alexandria

    OpenAIRE

    Luisa, Ferro; Giulio, Magli

    2012-01-01

    Alexander the Great founded Alexandria in 331 BC. The newly founded town was conceived as an orthogonal grid based on a main longitudinal axis, later called Canopic Road. We analyse here the astronomical orientation of the project and propose that the main axis was deliberately oriented towards the rising sun on the day of birth of Alexander the Great. The argument is admittedly speculative as any Archaeoastronomy argument not backed up by written sources. However, it is nested accurately int...

  7. A Case of Racial Discrimination: Azeglio Bemporad, Astronomer Poet

    Science.gov (United States)

    Mangano, A.

    2015-04-01

    The stories from our archives do not only speak of scientific progress, tools, and data, but also of the events of the astronomers as men, and how their work is intertwined in their private, political, and social life. In the case of Azeglio Bemporad, who worked at Catania Astrophysical Observatory until 1938, year of purge against Jews in Italy, the painful history of Fascism fully enters our scientific institutions, changing the life of a person who had never dealt with politics.

  8. Structure of matter and the structure of the astronomical universe

    International Nuclear Information System (INIS)

    Layzer, D.

    1977-01-01

    It is suggested that the central problem of modern cosmology, the origin of astronomical systems, may be closely related to certain problems in solid-state physics. The arguments presented therefore afford some grounds for the claim that cosmology is a province of quantum chemistry--as well as for the opposite claim that quantum chemistry is a province of cosmology. The diameter-mass relation, gravitational clustering, cold universe prehistory, and radiation backgrounds are considered

  9. Astronomers Travel in Time and Space with Light

    Science.gov (United States)

    Mather, John C.

    2016-01-01

    This is an excerpt of John Mather's in a book titled: INSPIRED BY LIGHT, Reflections from the International Year of Light 2015. It was produced in January 2016 by SPIE, the European Physical Society (EPS), and The Abdus Salam International Centre for Theoretical Physics (ICTP) to commemorate the International Year of Light and Light-based Technologies 2015. The excerpt discusses how astronomers use light.

  10. A Mythological, Philosophical and Astronomical approach of our solar system

    Science.gov (United States)

    Drivas, Sotirios; Kastanidou, Sofia

    2016-04-01

    Teaching Geography in the first Class of Gymnasium - secondary education we will focus in Solar System: Astronomical approach: Students will look and find the astronomical data of the planets, they will make comparisons between the sizes of their radius, they will find the distance from the Sun, they will search the relative motion, they will calculate the gravity on each planet, etc. Mythological approach: We will search the names and meanings of the planets based on Greek mythological origin. Philosophical approach: Regarding the philosophical approach of the "solar system" we will look and find: • Why planets are called so? • How did planets get their names? • What are the periods of Greek astronomy? • What were the astronomical instruments of ancient Greeks and who did built them? • What were the Greek philosophers and astronomers? When did they live and what did they discover? • Which method did Eratosthenes of Cyrene apply about 206B.C. to serve a real measurement of the earth's radius? • What was the relationship between science and religion in ancient Greece? Literature approach: At the end of the program students will write their opinion in subject "Having a friend from another planet" based on the book of Antoine de Saint - Exupéry "The little prince". Law approach: A jurist working in Secondary Education will visits our school and engages students in the Space Law. Artistic approach: Students will create their own posters of our planetary system. The best posters will be posted on the school bulletin board to display their work. Visit: Students and teachers will visit the Observatory of Larissa where they will see how observatory works and talk with scientists about their job. They will look through telescopes and observe the sun.

  11. Explaining formation of Astronomical Jets using Dynamic Universe Model

    Science.gov (United States)

    Naga Parameswara Gupta, Satyavarapu

    2016-07-01

    Astronomical jets are observed from the centres of many Galaxies including our own Milkyway. The formation of such jet is explained using SITA simulations of Dynamic Universe Model. For this purpose the path traced by a test neutron is calculated and depicted using a set up of one densemass of the mass equivalent to mass of Galaxy center, 90 stars with similar masses of stars near Galaxy center, mass equivalents of 23 Globular Cluster groups, 16 Milkyway parts, Andromeda and Triangulum Galaxies at appropriate distances. Five different kinds of theoretical simulations gave positive results The path travelled by this test neutron was found to be an astronomical jet emerging from Galaxy center. This is another result from Dynamic Universe Model. It solves new problems like a. Variable Mass Rocket Trajectory Problem b. Explaining Very long baseline interferometry (VLBI) observations c. Astronomical jets observed from Milkyway Center d. Prediction of Blue shifted Galaxies e. Explaining Pioneer Anomaly f. Prediction of New Horizons satellite trajectory etc. Dynamic Universe Model never reduces to General relativity on any condition. It uses a different type of mathematics based on Newtonian physics. This mathematics used here is simple and straightforward. As there are no differential equations present in Dynamic Universe Model, the set of equations give single solution in x y z Cartesian coordinates for every point mass for every time step

  12. Astronomical Image Compression Techniques Based on ACC and KLT Coder

    Directory of Open Access Journals (Sweden)

    J. Schindler

    2011-01-01

    Full Text Available This paper deals with a compression of image data in applications in astronomy. Astronomical images have typical specific properties — high grayscale bit depth, size, noise occurrence and special processing algorithms. They belong to the class of scientific images. Their processing and compression is quite different from the classical approach of multimedia image processing. The database of images from BOOTES (Burst Observer and Optical Transient Exploring System has been chosen as a source of the testing signal. BOOTES is a Czech-Spanish robotic telescope for observing AGN (active galactic nuclei and the optical transient of GRB (gamma ray bursts searching. This paper discusses an approach based on an analysis of statistical properties of image data. A comparison of two irrelevancy reduction methods is presented from a scientific (astrometric and photometric point of view. The first method is based on a statistical approach, using the Karhunen-Loeve transform (KLT with uniform quantization in the spectral domain. The second technique is derived from wavelet decomposition with adaptive selection of used prediction coefficients. Finally, the comparison of three redundancy reduction methods is discussed. Multimedia format JPEG2000 and HCOMPRESS, designed especially for astronomical images, are compared with the new Astronomical Context Coder (ACC coder based on adaptive median regression.

  13. The Amateur Astronomer's Introduction to the Celestial Sphere

    Science.gov (United States)

    Millar, William

    2005-12-01

    This introduction to the night sky is for amateur astronomers who desire a deeper understanding of the principles and observations of naked-eye astronomy. It covers topics such as terrestrial and astronomical coordinate systems, stars and constellations, the relative motions of the sky, sun, moon and earth leading to an understanding of the seasons, phases of the moon, and eclipses. Topics are discussed and compared for observers located in both the northern and southern hemispheres. Written in a conversational style, only addition and subtraction are needed to understand the basic principles and a more advanced mathematical treatment is available in the appendices. Each chapter contains a set of review questions and simple exercises to reinforce the reader's understanding of the material. The last chapter is a set of self-contained observation projects to get readers started with making observations about the concepts they have learned. William Charles Millar, currently Professor of Astronomy at Grand Rapids Community College in Michigan, has been teaching the subject for almost twenty years and is very involved with local amateur astronomy groups. Millar also belongs to The Planetary Society and the Astronomical Society of the Pacific and has traveled to Europe and South America to observe solar eclipses. Millar holds a Masters degree in Physics from Western Michigan University.

  14. The Production Rate and Employment of Ph.D. Astronomers

    Science.gov (United States)

    Metcalfe, Travis S.

    2008-02-01

    In an effort to encourage self-regulation of the astronomy job market, I examine the supply of, and demand for, astronomers over time. On the supply side, I document the production rate of Ph.D. astronomers from 1970 to 2006 using the UMI Dissertation Abstracts database, along with data from other independent sources. I compare the long-term trends in Ph.D. production with federal astronomy research funding over the same time period, and I demonstrate that additional funding is correlated with higher subsequent Ph.D. production. On the demand side, I monitor the changing patterns of employment using statistics about the number and types of jobs advertised in the AAS Job Register from 1984 to 2006. Finally, I assess the sustainability of the job market by normalizing this demand by the annual Ph.D. production. The most recent data suggest that there are now annual advertisements for about one postdoctoral job, half a faculty job, and half a research/support position for every new domestic Ph.D. recipient in astronomy and astrophysics. The average new astronomer might expect to hold up to 3 jobs before finding a steady position.

  15. Breakthrough! 100 astronomical images that changed the world

    CERN Document Server

    Gendler, Robert

    2015-01-01

    This unique volume by two renowned astrophotographers unveils the science and history behind 100 of the most significant astronomical images of all time. The authors have carefully selected their list of images from across time and technology to bring to the reader the most relevant photographic images spanning all eras of modern astronomical history.    Based on scientific evidence today we have a basic notion of how Earth and the universe came to be. The road to this knowledge was paved with 175 years of astronomical images acquired by the coupling of two revolutionary technologies – the camera and telescope. With ingenuity and determination humankind would quickly embrace these technologies to tell the story of the cosmos and unravel its mysteries.   This book presents in pictures and words a photographic chronology of our aspiration to understand the universe. From the first fledgling attempts to photograph the Moon, planets, and stars to the marvels of orbiting observatories that record the cosmos a...

  16. The War's Positive Impact on the Canadian Astronomical Community

    Science.gov (United States)

    Broughton, Peter

    2015-01-01

    At the beginning of WWI, the Canadian astronomical community was tiny and astrophysical research was just beginning. By the end of the war, the country had established the forerunner of its National Research Council and had the world's largest fully operational telescope, thanks to the late entry of the USA into the conflict. By 1918, Canada was on the verge of making significant contributions to science.In spite of the immense loss of life in this pointless war, I am aware of only one casualty affecting Canadian professional astronomers, and that was the indirect death of James Chant, son of University of Toronto's only professor of astronomy. Other Canadian astronomers, including Tom Parker, Bert Topham, and Harry Plaskett were on active service; each of their stories is unique.Among those engaged in scientific work during the war were two Canadians temporarily in England: John McLennan whose helium research for dirigibles led him to establish a cryogenic lab in Toronto where the green line in the spectrum of the aurora was identified in 1925, and Allie Douglas who worked as a statistician in the War Office. Later work with Eddington led her to become his biographer and to her distinction as the first person in Canada to earn a PhD in astronomy (in 1926).

  17. The Growth of Interest in Astronomical X-Ray Polarimetry

    Directory of Open Access Journals (Sweden)

    Frédéric Marin

    2018-03-01

    Full Text Available Astronomical X-ray polarimetry was first explored in the end of the 1960s by pioneering rocket instruments. The craze arising from the first discoveries of stellar and supernova remnant X-ray polarization led to the addition of X-ray polarimeters to early satellites. Unfortunately, the inadequacy of the diffraction and scattering technologies required to measure polarization with respect to the constraints driven by X-ray mirrors and detectors, coupled with long integration times, slowed down the field for almost 40 years. Thanks to the development of new, highly sensitive, compact X-ray polarimeters in the beginning of the 2000s, observing astronomical X-ray polarization has become feasible, and scientists are now ready to explore our high-energy sky thanks to modern X-ray polarimeters. In the forthcoming years, several X-ray missions (rockets, balloons, and satellites will create new observational opportunities. Interest in astronomical X-ray polarimetry field has thus been renewed, and this paper presents for the first time a quantitative assessment, all based on scientific literature, of the growth of this interest.

  18. Science Initiatives of the US Virtual Astronomical Observatory

    Science.gov (United States)

    Hanisch, R. J.

    2012-09-01

    The United States Virtual Astronomical Observatory program is the operational facility successor to the National Virtual Observatory development project. The primary goal of the US VAO is to build on the standards, protocols, and associated infrastructure developed by NVO and the International Virtual Observatory Alliance partners and to bring to fruition a suite of applications and web-based tools that greatly enhance the research productivity of professional astronomers. To this end, and guided by the advice of our Science Council (Fabbiano et al. 2011), we have focused on five science initiatives in the first two years of VAO operations: 1) scalable cross-comparisons between astronomical source catalogs, 2) dynamic spectral energy distribution construction, visualization, and model fitting, 3) integration and periodogram analysis of time series data from the Harvard Time Series Center and NASA Star and Exoplanet Database, 4) integration of VO data discovery and access tools into the IRAF data analysis environment, and 5) a web-based portal to VO data discovery, access, and display tools. We are also developing tools for data linking and semantic discovery, and have a plan for providing data mining and advanced statistical analysis resources for VAO users. Initial versions of these applications and web-based services are being released over the course of the summer and fall of 2011, with further updates and enhancements planned for throughout 2012 and beyond.

  19. Skype Me! Astronomers, Students, and Cutting-Edge Research

    Science.gov (United States)

    Hickox, Ryan C.; Gauthier, Adrienne J.

    2014-06-01

    A primary goal of many university science courses is to promote understanding of the process of contemporary scientific inquiry. One powerful way to achieve this is for students to explore current research and then interact directly with the leading scientist, the feasibility of which has recently increased dramatically due to free online video communication tools. We report on a program implemented at Dartmouth College in which students connect with a guest astronomer through Skype (video chat). The Skype session is wrapped in a larger activity where students explore current research articles, interact with the astronomer, and then reflect on the experience. The in-class Skype discussions require a small time commitment from scientists (20-30 minutes, with little or no need for preparation) while providing students direct access to researchers at the cutting edge of modern astronomy. We outline the procedures used to implement these discussions, and present qualitative assessments of student's understanding of the process of research, as well as feedback from the guest astronomers.

  20. Science Initiatives of the US Virtual Astronomical Observatory

    Directory of Open Access Journals (Sweden)

    Hanisch Robert J.

    2012-09-01

    Full Text Available The United States Virtual Astronomical Observatory program is the operational facility successor to the National Virtual Observatory development project. The primary goal of the US VAO is to build on the standards, protocols, and associated infrastructure developed by NVO and the International Virtual Observatory Alliance partners and to bring to fruition a suite of applications and web-based tools that greatly enhance the research productivity of professional astronomers. To this end, and guided by the advice of our Science Council (advisory committee, we are focusing on five science initiatives in the first two years of VAO operations: (1 scalable cross-comparisons between astronomical source catalogs, (2 dynamic spectral energy distribution construction, visualization, and model fitting, (3 integration and periodogram analysis of time series data from the Harvard Time Series Center and NASA Star and Exoplanet Database, (4 integration of VO data discovery and access tools into the IR AF data analysis environment, and (5 a web-based portal to VO data discovery, access, and display tools. We are also developing tools for data linking and semantic discovery, and have a plan for providing data mining and advanced statistical analysis resources for VAO users. Initial versions of these applications and web-based services are being released over the course of the summer and fall of 2011, with further updates and enhancements planned for throughout 2012 and beyond.

  1. Astronomical relativistic reference systems with multipolar expansion: the global one

    International Nuclear Information System (INIS)

    Xie Yi

    2014-01-01

    With the rapid development of techniques for astronomical observations, the precision of measurements has been significantly increasing. Theories describing astronomical relativistic reference systems, which are the foundation for processing and interpreting these data now and in the future, may require extensions to satisfy the needs of these trends. Besides building a framework compatible with alternative theories of gravity and the pursuit of higher order post-Newtonian approximation, it will also be necessary to make the first order post-Newtonian multipole moments of celestial bodies be explicitly expressed in the astronomical relativistic reference systems. This will bring some convenience into modeling the observations and experiments and make it easier to distinguish different contributions in measurements. As a first step, the global solar system reference system is expressed as a multipolar expansion and the post-Newtonian mass and spin moments are shown explicitly in the metric which describes the coordinates of the system. The full expression of the global metric is given. (research papers)

  2. Immersive 3D Visualization of Astronomical Data

    Science.gov (United States)

    Schaaff, A.; Berthier, J.; Da Rocha, J.; Deparis, N.; Derriere, S.; Gaultier, P.; Houpin, R.; Normand, J.; Ocvirk, P.

    2015-09-01

    The immersive-3D visualization, or Virtual Reality in our study, was previously dedicated to specific uses (research, flight simulators, etc.) The investment in infrastructure and its cost was reserved to large laboratories or companies. Lately we saw the development of immersive-3D masks intended for wide distribution, for example the Oculus Rift and the Sony Morpheus projects. The usual reaction is to say that these tools are primarily intended for games since it is easy to imagine a player in a virtual environment and the added value to conventional 2D screens. Yet it is likely that there are many applications in the professional field if these tools are becoming common. Introducing this technology into existing applications or new developments makes sense only if interest is properly evaluated. The use in Astronomy is clear for education, it is easy to imagine mobile and light planetariums or to reproduce poorly accessible environments (e.g., large instruments). In contrast, in the field of professional astronomy the use is probably less obvious and it requires to conduct studies to determine the most appropriate ones and to assess the contributions compared to the other display modes.

  3. Astronomical optical interferometry, II: Astrophysical results

    Directory of Open Access Journals (Sweden)

    Jankov S.

    2011-01-01

    Full Text Available Optical interferometry is entering a new age with several ground- based long-baseline observatories now making observations of unprecedented spatial resolution. Based on a great leap forward in the quality and quantity of interferometric data, the astrophysical applications are not limited anymore to classical subjects, such as determination of fundamental properties of stars; namely, their effective temperatures, radii, luminosities and masses, but the present rapid development in this field allowed to move to a situation where optical interferometry is a general tool in studies of many astrophysical phenomena. Particularly, the advent of long-baseline interferometers making use of very large pupils has opened the way to faint objects science and first results on extragalactic objects have made it a reality. The first decade of XXI century is also remarkable for aperture synthesis in the visual and near-infrared wavelength regimes, which provided image reconstructions from stellar surfaces to Active Galactic Nuclei. Here I review the numerous astrophysical results obtained up to date, except for binary and multiple stars milliarcsecond astrometry, which should be a subject of an independent detailed review, taking into account its importance and expected results at microarcsecond precision level. To the results obtained with currently available interferometers, I associate the adopted instrumental settings in order to provide a guide for potential users concerning the appropriate instruments which can be used to obtain the desired astrophysical information.

  4. Spectral atlas for amateur astronomers a guide to the spectra of astronomical objects and terrestrial light sources

    CERN Document Server

    Walker, Richard

    2017-01-01

    Featuring detailed commented spectral profiles of more than one hundred astronomical objects, in colour, this spectral guide documents most of the important and spectroscopically observable objects accessible using typical amateur equipment. It allows you to read and interpret the recorded spectra of the main stellar classes, as well as most of the steps from protostars through to the final stages of stellar evolution as planetary nebulae, white dwarfs or the different types of supernovae. It also presents integrated spectra of stellar clusters, galaxies and quasars, and the reference spectra of some terrestrial light sources, for calibration purposes. Whether used as the principal reference for comparing with your recorded spectra or for inspiring independent observing projects, this atlas provides a breathtaking view into our Universe's past. The atlas is accompanied and supplemented by Spectroscopy for Amateur Astronomers, which explains in detail the methods for recording, processing, analysing and interp...

  5. The caracol tower at chichen itza: an ancient astronomical observatory?

    Science.gov (United States)

    Aveni, A F; Gibbs, S L; Hartung, H

    1975-06-06

    Although our investigations reveal a number of significant astronomical events coinciding with many of the measured alignments presented in Table 1, not every alignment appears to have an astronomical match which we can recognize. It may be that only some of the sighting possibilities we have discussed were actually functional. Moreover, our search of significant astronomical events to match the alignments has included only those which seem of obvious functional importance to us: sun, moon, and planetary extremes and the setting positions of the brightest stars. We have emphasized those celestial bodies which are documented in the literature as having been of importance. Perhaps hitherto unrecognized constellations were sighted in the windows, perhaps fainter stars, the heliacal rising and setting times of which could have served to mark important dates in the calendar. While we propose no grand cosmic scheme for the astronomical design of the Caracol it can be inferred that the building, apart from being a monument related to Quetzalcoatl, was erected primarily for the purpose of embodying in its architecture certain significant astronomical event alignments, in the same sense that a modern astronomical ephemeris exhibits information of importance to us in the keeping of the current calendar. There are examples in the Mesoamerican historical literature of deliberate attempts to align buildings with astronomical directions of importance. For example, Maudslay (33) quotes Father Motolinia, who tells us that in Tenochtitlan the festival called Tlacaxipeualistli "took place when the sun stood in the middle of Huicholobos, which was at the equinox, and because it was a little out of the straight, Montezuma wished to pull it down and set it right." According to Maudslay, worshipers were probably facing east to watch the sun rise between the two oratories on the Great Temple of Tenochtitlan at the time of the equinox. The directions of the faces of the Lower and Upper

  6. Astronomers Win Protection for Key Part of Radio Spectrum

    Science.gov (United States)

    2000-06-01

    Astronomers using the millimeter-wave region of the radio spectrum have won crucial protection for their science. Dedicated allocations for radio astronomy have been given final approval by the 2,500 delegates to the World Radiocommunication Conference (WRC-00), which recently concluded a month of deliberations in Istanbul, Turkey. Radio services can transmit in these parts of the spectrum as long as they don't hinder astronomers' attempts to catch faint signals from the cosmos. The new allocations represent the culmination of more than three years of cooperative planning by radio astronomers in many countries. Millimeter waves -- high-frequency radio waves -- have come of age as an astronomical tool in the last ten years. They are one of the last technological frontiers for astronomers. WRC-00 has protected for science all the frequencies between 71 and 275 Gigahertz (GHz) that radio astronomers currently use, adding more than 90 GHz of spectrum to the 44 GHz already set aside in this frequency range. As a result, radio astronomy is now allocated most of the frequencies between 71 and 275 GHz that can get through the Earth's atmosphere. "We have formal access to all three atmospheric 'windows', apart from their very edges," said Dr. Tom Gergely of the National Science Foundation, one of the U.S. delegates to WRC-00. The WRC also changed most of the frequencies allocated to satellite downlinks within the 71-275 GHz range to frequencies not used for science. Since no satellites yet operate at these high frequencies, no equipment needs to be altered. "Commercial technologies are just starting to develop above 50 GHz," said Dr. Klaus Ruf, Chairman of the Inter-Union Commission for the Allocation of Frequencies. "The WRC's actions mean that, when they are, radio astronomers should be able to share this part of the spectrum with most terrestrial services." The World Radiocommunication Conference is held every two or three years. Here member countries of the

  7. ALOHA—Astronomical Light Optical Hybrid Analysis - From experimental demonstrations to a MIR instrument proposal

    Science.gov (United States)

    Lehmann, L.; Darré, P.; Szemendera, L.; Gomes, J. T.; Baudoin, R.; Ceus, D.; Brustlein, S.; Delage, L.; Grossard, L.; Reynaud, F.

    2018-04-01

    This paper gives an overview of the Astronomical Light Optical Hybrid Analysis (ALOHA) project dedicated to investigate a new method for high resolution imaging in mid infrared astronomy. This proposal aims to use a non-linear frequency conversion process to shift the thermal infrared radiation to a shorter wavelength domain compatible with proven technology such as guided optics and detectors. After a description of the principle, we summarise the evolution of our study from the high flux seminal experiments to the latest results in the photon counting regime.

  8. Orion in Homer: is it a Terrestrial, an Astral or an Astronomical Myth?

    Science.gov (United States)

    Revello, Manuela

    2015-05-01

    In Greek literature the subjects that relate to stars and constellations are very complex. Various studies are involved in this field of investigation, such as those of astronomy, astrology, mythology, astral-metereology and philology; the situation becomes even more complicated when we attempt to reconstruct a picture of the knowledge of the stars and the relative degree of consciousness of this matter existent during the Homeric age. In this brief report we shall look at the constellation of Orion. The discussed arguments will point out the sharp differences that exist between terrestrial, astronomical and astral myths.

  9. Light pollution in Valencian Natural Parks: where light not only annoys astronomers

    Science.gov (United States)

    Marco, E.; Morales Rubio, A.; Bullón, J. M.

    2013-05-01

    Street lighting of the city of Valencia produces a yellowish halo that prevents astronomical observation. Moreover, within the metropolitan area, there are three natural parks: the Parc Natural de l'Albufera, the Parc Natural del Túria and the Parc Natural de la Calderona. The light pollution affects the nighttime wildlife parks. Therefore, since 2010, a campaign is being carried out in order to collect data but also to raise awareness and reporting of the harmful effects of excessive and incorrect installation of existing luminaires. Since 2012 this study has been extended to other Valencian natural parks far from Valencia. Their sky darkness is a value to preserve.

  10. Catching Stardust and Bringing it Home: The Astronomical Importance of Sample Return

    Science.gov (United States)

    Brownlee, D.

    2002-12-01

    The return of lunar samples by the Apollo program provided the first opportunity to perform detailed laboratory studies of ancient solid materials from a known astronomical body. The highly detailed study of the samples, using the best available laboratory instruments and techniques, revolutionized our understanding of the Moon and provided fundamental insight into the remarkable and violent processes that occur early in the history of moons and terrestrial planets. This type of astronomical paleontology is only possible with samples and yet the last US sample return was made by Apollo 17- over thirty years ago! The NASA Stardust mission, began a new era of sample missions with its 1999 launch to retrieve samples from the short period comet Wild 2. Genesis (a solar wind collector) was launched in 2001, the Japanese MUSES-C asteroid sample return mission will launch in 2003 and Mars sample return missions are under study. All of these missions will use sophisticated ground-based instrumentation to provide types of information that cannot be obtained by astronomical and spacecraft remote sensing methods. In the case of Stardust, the goal is to determine the fundamental nature of the initial solid building blocks of solar systems at atomic-scale spatial resolution. The samples returned by the mission will be samples from the Kuiper Belt region and they are probably composed of submicron silicate and organic materials of both presolar and nebular origin. Unlocking the detailed records contained in the elemental, chemical, isotopic and mineralogical composition of these tiny components can only be appropriately explored with full power, precision and flexibility of laboratory instrumentation. Laboratory instrumentation has the advantage that is state-of-the-art and is not limited by serious considerations of power, mass, cost or even reliability. The comparison of the comet sample, accumulated beyond Neptune, with asteroidal meteorites that accumulated just beyond the

  11. Low Dimensional Embedding of Climate Data for Radio Astronomical Site Testing in the Colombian Andes

    Science.gov (United States)

    Chaparro Molano, Germán; Ramírez Suárez, Oscar Leonardo; Restrepo Gaitán, Oscar Alberto; Marcial Martínez Mercado, Alexander

    2017-10-01

    We set out to evaluate the potential of the Colombian Andes for millimeter-wave astronomical observations. Previous studies for astronomical site testing in this region have suggested that nighttime humidity and cloud cover conditions make most sites unsuitable for professional visible-light observations. Millimeter observations can be done during the day, but require that the precipitable water vapor column above a site stays below ˜10 mm. Due to a lack of direct radiometric or radiosonde measurements, we present a method for correlating climate data from weather stations to sites with a low precipitable water vapor column. We use unsupervised learning techniques to low dimensionally embed climate data (precipitation, rain days, relative humidity, and sunshine duration) in order to group together stations with similar long-term climate behavior. The data were taken over a period of 30 years by 2046 weather stations across the Colombian territory. We find six regions with unusually dry, clear-sky conditions, ranging in elevations from 2200 to 3800 masl. We evaluate the suitability of each region using a quality index derived from a Bayesian probabilistic analysis of the station type and elevation distributions. Two of these regions show a high probability of having an exceptionally low precipitable water vapor column. We compared our results with global precipitable water vapor maps and find a plausible geographical correlation with regions with low water vapor columns (˜10 mm) at an accuracy of ˜20 km. Our methods can be applied to similar data sets taken in other countries as a first step toward astronomical site evaluation.

  12. Effect of a hydrophilic and a hydrophobic statin on cardiac salvage after ST-elevated acute myocardial infarction - a pilot study.

    Science.gov (United States)

    Chitose, Tadasuke; Sugiyama, Seigo; Sakamoto, Kenji; Shimomura, Hideki; Yamashita, Takuro; Hokamaki, Jun; Tsunoda, Ryusuke; Shiraishi, Shinya; Yamashita, Yasuyuki; Ogawa, Hisao

    2014-11-01

    Early statin therapy after acute coronary syndrome reduces atherothrombotic vascular events. This study aimed to compare the effects of hydrophilic and hydrophobic statins on myocardial salvage and left ventricular (LV) function in patients with ST-elevated myocardial infarction (STEMI). Seventy-five STEMI patients who had received emergency reperfusion therapy were enrolled and randomized into the hydrophilic statin group (rosuvastatin; 5 mg/day, n = 38) and hydrophobic statin group (atorvastatin; 10 mg/day, n = 37) for 6 months. LV ejection fraction (LVEF), and B-type natriuretic peptide (BNP) and co-enzyme Q10 (CoQ10) levels were measured at baseline and the end of treatment. The myocardial salvage index was assessed by single photon emission computed tomography with (123-)I-β-methyl-iodophenylpentadecanoic acid (ischemic area-at-risk at onset of STEMI: AAR) and (201-)thallium scintigraphy (area-at-infarction at 6 months: AAI) [myocardial salvage index = (AAR-AAI) × 100/AAR (%)]. Onset-to-balloon time and maximum creatine phosphokinase levels were comparable between the groups. After 6 months, rosuvastatin (-37.6% ± 17.2%) and atorvastatin (-32.4% ± 22.4%) equally reduced low-density lipoprotein-cholesterol (LDL-C) levels (p = 0.28). However, rosuvastatin (+3.1% ± 5.9%, p < 0.05), but not atorvastatin (+1.6% ± 5.7%, p = 0.15), improved LVEF. Rosuvastatin reduced BNP levels compared with atorvastatin (-53.3% ± 48.8% versus -13.8% ± 82.9%, p < 0.05). The myocardial salvage index was significantly higher in the rosuvastatin group than the atorvastatin group (78.6% ± 29.1% versus 52.5% ± 38.0%, p < 0.05). CoQ10/LDL-C levels at 6 months were increased in the rosuvastatin group (+23.5%, p < 0.01) and percent changes in CoQ10/LDL-C were correlated with the myocardial salvage index (r = 0.56, p < 0.01). Rosuvastatin shows better beneficial effects on myocardial salvage than atorvastatin in STEMI patients, including long-term cardiac function, associated with

  13. A novel type of very long baseline astronomical intensity interferometer

    Science.gov (United States)

    Borra, Ermanno F.

    2013-12-01

    This article presents a novel type of very long baseline astronomical interferometer that uses the fluctuations, as a function of time, of the intensity measured by a quadratic detector, which is a common type of astronomical detector. The theory on which the technique is based is validated by laboratory experiments. Its outstanding principal advantages comes from the fact that the angular structure of an astronomical object is simply determined from the visibility of the minima of the spectrum of the intensity fluctuations measured by the detector, as a function of the frequency of the fluctuations, while keeping the spacing between mirrors constant. This would allow a simple setup capable of high angular resolutions because it could use an extremely large baseline. Another major interest is that it allows for a more efficient use of telescope time because observations at a single baseline are sufficient, while amplitude and intensity interferometers need several observations at different baselines. The fact that one does not have to move the telescopes would also allow detecting faster time variations because having to move the telescopes sets a lower limit to the time variations that can be detected. The technique uses wave interaction effects and thus has some characteristics in common with intensity interferometry. A disadvantage of the technique, like in intensity interferometry, is that it needs strong sources if observing at high frequencies (e.g. the visible). This is a minor disadvantage in the radio region. At high frequencies, this disadvantage is mitigated by the fact that, like in intensity interferometry, the requirements of the optical quality of the mirrors used are far less severe than in amplitude interferometry so that poor quality large reflectors (e.g. Cherenkov telescopes) can be used in the optical region.

  14. The Red Rectangle: An Astronomical Example of Mach Bands?

    Science.gov (United States)

    Brecher, K.

    2005-12-01

    Recently, the Hubble Space Telescope (HST) produced spectacular images of the "Red Rectangle". This appears to be a binary star system undergoing recurrent mass loss episodes. The image-processed HST photographs display distinctive diagonal lightness enhancements. Some of the visual appearance undoubtedly arises from actual variations in the luminosity distribution of the light of the nebula itself, i.e., due to limb brightening. Psychophysical enhancement similar to the Vasarely or pyramid effect also seems to be involved in the visual impression conveyed by the HST images. This effect is related to Mach bands (as well as to the Chevreul and Craik-O'Brien-Cornsweet effects). The effect can be produced by stacking concentric squares (or other geometrical figures such as rectangles or hexagons) of linearly increasing or decreasing size and lightness, one on top of another. We have constructed controllable Flash applets of this effect as part of the NSF supported "Project LITE: Light Inquiry Through Experiments". They can be found in the vision section of the LITE web site at http://lite.bu.edu. Mach band effects have previously been seen in medical x-ray images. Here we report for the first time the possibility that such effects play a role in the interpretation of astronomical images. Specifically, we examine to what extent the visual impressions of the Red Rectangle and other extended astronomical objects are purely physical (photometric) in origin and to what degree they are enhanced by psychophysical processes. To help assess the relative physical and psychophysical contributions to the perceived lightness effects, we have made use of a center-surround (Difference of Gaussians) filter we developed for MatLab. We conclude that local (lateral inhibition) and longer range human visual perception effects probably do contribute to the lightness features seen in astronomical objects like the Red Rectangle. Project LITE is supported by NSF Grant # DUE-0125992.

  15. In the Jungle of Astronomical On--line Data Services

    Science.gov (United States)

    Egret, D.

    The author tried to survive in the jungle of astronomical on--line data services. In order to find efficient answers to common scientific data retrieval requests, he had to collect many pieces of information, in order to formulate typical user scenarios, and try them against a number of different data bases, catalogue services, or information systems. He discovered soon how frustrating treasure coffers may be when their keys are not available, but he realized also that nice widgets and gadgets are of no help when the information is not there. And, before long, he knew he would have to navigate through several systems because no one was yet offering a general answer to all his questions. I will present examples of common user scenarios and show how they were tested against a number of services. I will propose some elements of classification which should help the end-user to evaluate how adequate the different services may be for providing satisfying answers to specific queries. For that, many aspects of the user interaction will be considered: documentation, access, query formulation, functionalities, qualification of the data, overall efficiency, etc. I will also suggest possible improvements to the present situation: the first of them being to encourage system managers to increase collaboration between one another, for the benefit of the whole astronomical community. The subjective review I will present, is based on publicly available astronomical on--line services from the U.S. and from Europe, most of which (excepting the newcomers) were described in ``Databases and On-Line Data in Astronomy", (Albrecht & Egret, eds, 1991): this includes databases (such as NED and Simbad ), catalog services ( StarCat , DIRA , XCatScan , etc.), and information systems ( ADS and ESIS ).

  16. SIP: A Web-Based Astronomical Image Processing Program

    Science.gov (United States)

    Simonetti, J. H.

    1999-12-01

    I have written an astronomical image processing and analysis program designed to run over the internet in a Java-compatible web browser. The program, Sky Image Processor (SIP), is accessible at the SIP webpage (http://www.phys.vt.edu/SIP). Since nothing is installed on the user's machine, there is no need to download upgrades; the latest version of the program is always instantly available. Furthermore, the Java programming language is designed to work on any computer platform (any machine and operating system). The program could be used with students in web-based instruction or in a computer laboratory setting; it may also be of use in some research or outreach applications. While SIP is similar to other image processing programs, it is unique in some important respects. For example, SIP can load images from the user's machine or from the Web. An instructor can put images on a web server for students to load and analyze on their own personal computer. Or, the instructor can inform the students of images to load from any other web server. Furthermore, since SIP was written with students in mind, the philosophy is to present the user with the most basic tools necessary to process and analyze astronomical images. Images can be combined (by addition, subtraction, multiplication, or division), multiplied by a constant, smoothed, cropped, flipped, rotated, and so on. Statistics can be gathered for pixels within a box drawn by the user. Basic tools are available for gathering data from an image which can be used for performing simple differential photometry, or astrometry. Therefore, students can learn how astronomical image processing works. Since SIP is not part of a commercial CCD camera package, the program is written to handle the most common denominator image file, the FITS format.

  17. Managing distributed software development in the Virtual Astronomical Observatory

    Science.gov (United States)

    Evans, Janet D.; Plante, Raymond L.; Boneventura, Nina; Busko, Ivo; Cresitello-Dittmar, Mark; D'Abrusco, Raffaele; Doe, Stephen; Ebert, Rick; Laurino, Omar; Pevunova, Olga; Refsdal, Brian; Thomas, Brian

    2012-09-01

    The U.S. Virtual Astronomical Observatory (VAO) is a product-driven organization that provides new scientific research capabilities to the astronomical community. Software development for the VAO follows a lightweight framework that guides development of science applications and infrastructure. Challenges to be overcome include distributed development teams, part-time efforts, and highly constrained schedules. We describe the process we followed to conquer these challenges while developing Iris, the VAO application for analysis of 1-D astronomical spectral energy distributions (SEDs). Iris was successfully built and released in less than a year with a team distributed across four institutions. The project followed existing International Virtual Observatory Alliance inter-operability standards for spectral data and contributed a SED library as a by-product of the project. We emphasize lessons learned that will be folded into future development efforts. In our experience, a well-defined process that provides guidelines to ensure the project is cohesive and stays on track is key to success. Internal product deliveries with a planned test and feedback loop are critical. Release candidates are measured against use cases established early in the process, and provide the opportunity to assess priorities and make course corrections during development. Also key is the participation of a stakeholder such as a lead scientist who manages the technical questions, advises on priorities, and is actively involved as a lead tester. Finally, frequent scheduled communications (for example a bi-weekly tele-conference) assure issues are resolved quickly and the team is working toward a common vision.

  18. Kepler-Astronomer in Astrology and Astrologer in Astronomy

    Science.gov (United States)

    Fempl-Madjarevic, Jasna

    The author is discussing a very complicated subject: the astrological aspects in the scientific activity of Johannes Kepler. Sometimes Kepler is considered the last astronomer which confused astrology with astronomy. In fact he composed horoscopes, but he was conscious finally that the astrology was a confusion. The author is discussing also the mistic aspects of the scientifc creation by Kepler. Particularly she emphasized that the "Mysterium Cosmographicum" is one of such works. Meanwhile, that work led to discovery of famous third laws of planets motion.

  19. Hera: High Energy Astronomical Data Analysis via the Internet

    Science.gov (United States)

    Valencic, Lynne A.; Chai, P.; Pence, W.; Snowden, S.

    2011-09-01

    The HEASARC at NASA Goddard Space Flight Center has developed Hera, a data processing facility for analyzing high energy astronomical data over the internet. Hera provides all the software packages, disk space, and computing resources needed to do general processing of and advanced research on publicly available data from High Energy Astrophysics missions. The data and data products are kept on a server at GSFC and can be downloaded to a user's local machine. This service is provided for free to students, educators, and researchers for educational and research purposes.

  20. Mingantu, 18th-Century Mongol Astronomer and Radioheliograph Namesake

    Science.gov (United States)

    Pasachoff, Jay M.

    2013-01-01

    The 18th-century Mongol astronomer Mingantu (1692-1765) has been honored with a city named after him and a nearby solar telescope array. During the IAU/Beijing, my wife and I went to the new Chinese solar radioheliograph, the Mingantu Observing Station, in Inner Mongolia, ~400 km northwest of Beijing, a project of the National Astronomical Observatories, Chinese Academy of Sciences. It currently contains 40 dishes each 4.5 m across, with a correlator from Beijing. Within a year, 60 2-m dishes will be added. We passed by the 12-century ruins of Xanadu (about 20 km north of Zhangbei) about halfway. The radioheliograph is in a plane about 1 km across, forming a three-armed spiral for interferometric solar mapping, something colleagues and I had carried out with the Jansky Very Large Array, taking advantage of the lunar occultation before annularity at the 20 May 2012 solar eclipse. In the central square of Mingantu city, a statue ~10-m high of the Mongol astronomer Mingantu appears. Its base bears a plaque ~1-m high of IAU Minor Planet Circular MPC 45750 announcing the naming in 2002 of asteroid 28242 Mingantu, discovered at a Chinese observatory in 1999. Mingantu carried out orbital calculations, mapping, mathematical work on infinite series, and other scientific research. He is honored by a modern museum behind the statue. The museum's first 40% describes Mingantu and his work, and is followed by some artifacts of the region from thousands of years ago. The final, large room contains a two-meter-square scale model of the radioheliograph, flat-screen televisions running Solar Dynamics Observatory and other contemporary visualizations, orreries and other objects, and large transparencies of NASA and other astronomical imagery. See my post at http://www.skyandtelescope.com/community/skyblog/newsblog/ specfically Astro-Sightseeing_in_Inner_Mongolia-167712965.html. We thank Yihua Yan for arranging the visit and Wang Wei (both NAOC) for accompanying us. My solar research

  1. ASTRONOMICAL PLATE ARCHIVES AND SUPERMASSIVE BLACK HOLE BINARIES

    Directory of Open Access Journals (Sweden)

    René Hudec

    2013-12-01

    Full Text Available The recent extensive digitisation of astronomical photographic plate archives, the development of new dedicated software and the use of powerful computers have for the first time enabled effective data mining in extensive plate databases, with wide applications in various fields of recent astrophysics. As an example, analyses of supermassive binary black holes (binary blazars require very long time intervals (50 years and more, which cannot be provided by other data sources. Examples of data obtained from data mining in plate archives are presented and briefly discussed.

  2. Illustrated Guide to Astronomical Wonders From Novice to Master Observer

    CERN Document Server

    Thompson, Robert

    2011-01-01

    With the advent of inexpensive, high-power telescopes priced at under 250, amateur astronomy is now within the reach of anyone, and this is the ideal book to get you started. The Illustrated Guide to Astronomical Wonders offers you a guide to the equipment you need, and shows you how and where to find hundreds of spectacular objects in the deep sky -- double and multiple stars as well as spectacular star clusters, nebulae, and galaxies. You get a solid grounding in the fundamental concepts and terminology of astronomy, and specific advice about choosing, buying, using, and maintaining the eq

  3. Tot Graeci Tot Sententiae: Astronomical Perspective Multiplicity in Ancient Greece

    Science.gov (United States)

    Longo, O.

    2011-06-01

    Ancient Greece was made of a multiplicity of thinking heads, in an atmosphere of (relative) freedom of opinions, in every field of knowledge. then we should not wonder if many astronomical and cosmological theories, survived until our 17th century, had already been formulated by different philosophers and in different regions, cities and periods of Greek history. Geocentric and heliocentric theories, as well as an atomistic theory of an infinite universe (with infinite worlds), could survive without crashing with one another. In the same time, religious opinions regarding the planets and Sun as a series of gods were present, however not on a scientific ground.

  4. The Future is Hera! Analyzing Astronomical Over the Internet

    Science.gov (United States)

    Valencic, L. A.; Chai, P.; Pence, W.; Shafer, R.; Snowden, S.

    2008-01-01

    Hera is the data processing facility provided by the High Energy Astrophysics Science Archive Research Center (HEASARC) at the NASA Goddard Space Flight Center for analyzing astronomical data. Hera provides all the pre-installed software packages, local disk space, and computing resources need to do general processing of FITS format data files residing on the users local computer, and to do research using the publicly available data from the High ENergy Astrophysics Division. Qualified students, educators and researchers may freely use the Hera services over the internet of research and educational purposes.

  5. Towards a robust and consistent middle Eocene astronomical timescale

    Science.gov (United States)

    Boulila, Slah; Vahlenkamp, Maximilian; De Vleeschouwer, David; Laskar, Jacques; Yamamoto, Yuhji; Pälike, Heiko; Kirtland Turner, Sandra; Sexton, Philip F.; Westerhold, Thomas; Röhl, Ursula

    2018-03-01

    Until now, the middle Eocene has remained a poorly constrained interval of efforts to produce an astrochronological timescale for the entire Cenozoic. This has given rise to a so-called "Eocene astronomical timescale gap" (Vandenberghe et al., 2012). A high-resolution astrochronological calibration for this interval has proven to be difficult to realize, mainly because carbonate-rich deep-marine sequences of this age are scarce. In this paper, we present records from middle Eocene carbonate-rich sequences from the North Atlantic Southeast Newfoundland Ridge (IODP Exp. 342, Sites U1408 and U1410), of which the cyclical sedimentary patterns allow for an orbital calibration of the geologic timescale between ∼38 and ∼48 Ma. These carbonate-rich cyclic sediments at Sites U1408 and U1410 were deposited as drift deposits and exhibit prominent lithological alternations (couplets) between greenish nannofossil-rich clay and white nannofossil ooze. The principal lithological couplet is driven by the obliquity of Earth's axial tilt, and the intensity of their expression is modulated by a cyclicity of about 173 kyr. This cyclicity corresponds to the interference of secular frequencies s3 and s6 (related to the precession of nodes of the Earth and Saturn, respectively). This 173-kyr obliquity amplitude modulation cycle is exceptionally well recorded in the XRF (X-ray fluorescence)-derived Ca/Fe ratio. In this work, we first demonstrate the stability of the (s3-s6) cycles using the latest astronomical solutions. Results show that this orbital component is stable back to at least 50 Ma, and can thus serve as a powerful geochronometer in the mid-Eocene portion of the Cenozoic timescale. We then exploit this potential by calibrating the geochronology of the recovered middle Eocene timescale between magnetic polarity Chrons C18n.1n and C21n. Comparison with previous timescales shows similarities, but also notable differences in durations of certain magnetic polarity chrons. We

  6. Stray radiation and the Infrared Astronomical Satellite /IRAS/ telescope

    Science.gov (United States)

    Noll, R. J.; Harned, R.; Breault, R. P.; Malugin, R.

    1981-01-01

    Stray light control is a major consideration in the design of infrared cryogenically cooled telescopes such as the Infrared Astronomical Satellite (IRAS). The basic design of the baffle system, and the placement, shape, and coating of the secondary support struts for the telescope subsystem are described. The intent of this paper is to highlight the stray light problems encountered while designing the system, and to illustrate how computer analysis can be a useful design aid. Scattering measurements of the primary mirror, and a full system level scatter measurement are presented. Comparisons of predicted performance with the measured results are also presented.

  7. Relationship between angina pectoris and outcomes in patients with heart failure and reduced ejection fraction: an analysis of the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA).

    Science.gov (United States)

    Badar, Athar A; Perez-Moreno, Ana Cristina; Jhund, Pardeep S; Wong, Chih M; Hawkins, Nathaniel M; Cleland, John G F; van Veldhuisen, Dirk J; Wikstrand, John; Kjekshus, John; Wedel, Hans; Watkins, Stuart; Gardner, Roy S; Petrie, Mark C; McMurray, John J V

    2014-12-21

    Angina pectoris is common in patients with heart failure and reduced ejection fraction (HF-REF) but its relationship with outcomes has not been well defined. This relationship was investigated further in a retrospective analysis of the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA). Four thousand, eight hundred and seventy-eight patients were divided into three categories: no history of angina and no chest pain at baseline (Group A; n = 1240), past history of angina but no chest pain at baseline (Group B; n = 1353) and both a history of angina and chest pain at baseline (Group C; n = 2285). Outcomes were examined using Kaplan-Meier and Cox regression survival analysis. Compared with Group A, Group C had a higher risk of non-fatal myocardial infarction or unstable angina (HR: 2.36, 1.54-3.61; P angina are at an increased risk of acute coronary syndrome and HF hospitalization. Whether these patients would benefit from more aggressive medical therapy or percutaneous revascularization is not known and merits further investigation. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: journals.permissions@oup.com.

  8. STUDIES IN ASTRONOMICAL TIME SERIES ANALYSIS. VI. BAYESIAN BLOCK REPRESENTATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Scargle, Jeffrey D. [Space Science and Astrobiology Division, MS 245-3, NASA Ames Research Center, Moffett Field, CA 94035-1000 (United States); Norris, Jay P. [Physics Department, Boise State University, 2110 University Drive, Boise, ID 83725-1570 (United States); Jackson, Brad [The Center for Applied Mathematics and Computer Science, Department of Mathematics, San Jose State University, One Washington Square, MH 308, San Jose, CA 95192-0103 (United States); Chiang, James, E-mail: jeffrey.d.scargle@nasa.gov [W. W. Hansen Experimental Physics Laboratory, Kavli Institute for Particle Astrophysics and Cosmology, Department of Physics and SLAC National Accelerator Laboratory, Stanford University, Stanford, CA 94305 (United States)

    2013-02-20

    This paper addresses the problem of detecting and characterizing local variability in time series and other forms of sequential data. The goal is to identify and characterize statistically significant variations, at the same time suppressing the inevitable corrupting observational errors. We present a simple nonparametric modeling technique and an algorithm implementing it-an improved and generalized version of Bayesian Blocks-that finds the optimal segmentation of the data in the observation interval. The structure of the algorithm allows it to be used in either a real-time trigger mode, or a retrospective mode. Maximum likelihood or marginal posterior functions to measure model fitness are presented for events, binned counts, and measurements at arbitrary times with known error distributions. Problems addressed include those connected with data gaps, variable exposure, extension to piecewise linear and piecewise exponential representations, multivariate time series data, analysis of variance, data on the circle, other data modes, and dispersed data. Simulations provide evidence that the detection efficiency for weak signals is close to a theoretical asymptotic limit derived by Arias-Castro et al. In the spirit of Reproducible Research all of the code and data necessary to reproduce all of the figures in this paper are included as supplementary material.

  9. Studies in Astronomical Time Series Analysis. VI. Bayesian Block Representations

    Science.gov (United States)

    Scargle, Jeffrey D.; Norris, Jay P.; Jackson, Brad; Chiang, James

    2013-01-01

    This paper addresses the problem of detecting and characterizing local variability in time series and other forms of sequential data. The goal is to identify and characterize statistically significant variations, at the same time suppressing the inevitable corrupting observational errors. We present a simple nonparametric modeling technique and an algorithm implementing it-an improved and generalized version of Bayesian Blocks [Scargle 1998]-that finds the optimal segmentation of the data in the observation interval. The structure of the algorithm allows it to be used in either a real-time trigger mode, or a retrospective mode. Maximum likelihood or marginal posterior functions to measure model fitness are presented for events, binned counts, and measurements at arbitrary times with known error distributions. Problems addressed include those connected with data gaps, variable exposure, extension to piece- wise linear and piecewise exponential representations, multivariate time series data, analysis of variance, data on the circle, other data modes, and dispersed data. Simulations provide evidence that the detection efficiency for weak signals is close to a theoretical asymptotic limit derived by [Arias-Castro, Donoho and Huo 2003]. In the spirit of Reproducible Research [Donoho et al. (2008)] all of the code and data necessary to reproduce all of the figures in this paper are included as auxiliary material.

  10. Astronomical Plate Archives and Binary Blazars Studies Rene Hudec

    Indian Academy of Sciences (India)

    Faculty of Electrical Engineering, Technicka 2, Prague 6, Czech Republic. e-mail: ... development of dedicated software, enables for the first time, effective data mining and data analyses by powerful computers with these archives. Examples of ...

  11. STUDIES IN ASTRONOMICAL TIME SERIES ANALYSIS. VI. BAYESIAN BLOCK REPRESENTATIONS

    International Nuclear Information System (INIS)

    Scargle, Jeffrey D.; Norris, Jay P.; Jackson, Brad; Chiang, James

    2013-01-01

    This paper addresses the problem of detecting and characterizing local variability in time series and other forms of sequential data. The goal is to identify and characterize statistically significant variations, at the same time suppressing the inevitable corrupting observational errors. We present a simple nonparametric modeling technique and an algorithm implementing it—an improved and generalized version of Bayesian Blocks—that finds the optimal segmentation of the data in the observation interval. The structure of the algorithm allows it to be used in either a real-time trigger mode, or a retrospective mode. Maximum likelihood or marginal posterior functions to measure model fitness are presented for events, binned counts, and measurements at arbitrary times with known error distributions. Problems addressed include those connected with data gaps, variable exposure, extension to piecewise linear and piecewise exponential representations, multivariate time series data, analysis of variance, data on the circle, other data modes, and dispersed data. Simulations provide evidence that the detection efficiency for weak signals is close to a theoretical asymptotic limit derived by Arias-Castro et al. In the spirit of Reproducible Research all of the code and data necessary to reproduce all of the figures in this paper are included as supplementary material.

  12. A buyer's and user's guide to astronomical telescopes and binoculars

    CERN Document Server

    Mullaney, James

    2014-01-01

    Amateur astronomers of all skill levels are always contemplating their next telescope, and this book points the way to the most suitable instruments. Similarly, those who are buying their first telescopes – and these days not necessarily a low-cost one – will be able to compare and contrast different types and manufacturers. This revised new guide provides an extensive overview of binoculars and telescopes. It includes detailed up-to-date information on sources, selection and use of virtually every major type, brand, and model on today’s market, a truly invaluable treasure-trove of information and helpful advice for all amateur astronomers. Originally written in 2006, much of the first edition is inevitably now out of date, as equipment advances and manufacturers come and go. This second edition not only updates all the existing sections but adds two new ones: Astro-imaging and Professional-Amateur collaboration. Thanks to the rapid and amazing developments that have been made in digital cameras it is...

  13. Astronomical Polarimetry with the RIT Polarization Imaging Camera

    Science.gov (United States)

    Vorobiev, Dmitry V.; Ninkov, Zoran; Brock, Neal

    2018-06-01

    In the last decade, imaging polarimeters based on micropolarizer arrays have been developed for use in terrestrial remote sensing and metrology applications. Micropolarizer-based sensors are dramatically smaller and more mechanically robust than other polarimeters with similar spectral response and snapshot capability. To determine the suitability of these new polarimeters for astronomical applications, we developed the RIT Polarization Imaging Camera to investigate the performance of these devices, with a special attention to the low signal-to-noise regime. We characterized the device performance in the lab, by determining the relative throughput, efficiency, and orientation of every pixel, as a function of wavelength. Using the resulting pixel response model, we developed demodulation procedures for aperture photometry and imaging polarimetry observing modes. We found that, using the current calibration, RITPIC is capable of detecting polarization signals as small as ∼0.3%. The relative ease of data collection, calibration, and analysis provided by these sensors suggest than they may become an important tool for a number of astronomical targets.

  14. Authentic Astronomical Discovery in Planetariums: Bringing Data to Domes

    Science.gov (United States)

    Wyatt, Ryan Jason; Subbarao, Mark; Christensen, Lars; Emmons, Ben; Hurt, Robert

    2018-01-01

    Planetariums offer a unique opportunity to disseminate astronomical discoveries using data visualization at all levels of complexity: the technical infrastructure to display data and a sizeable cohort of enthusiastic educators to interpret results. “Data to Dome” is an initiative the International Planetarium Society to develop our community’s capacity to integrate data in fulldome planetarium systems—including via open source software platforms such as WorldWide Telescope and OpenSpace. We are cultivating a network of planetarium professionals who integrate data into their presentations and share their content with others. Furthermore, we propose to shorten the delay between discovery and dissemination in planetariums. Currently, the “latest science” is often presented days or weeks after discoveries are announced, and we can shorten this to hours or even minutes. The Data2Dome (D2D) initiative, led by the European Southern Observatory, proposes technical infrastructure and data standards that will streamline content flow from research institutions to planetariums, offering audiences a unique opportunity to access to the latest astronomical data in near real time.

  15. Authentic Astronomical Discovery in Planetariums: Data-Driven Immersive Lectures

    Science.gov (United States)

    Wyatt, Ryan Jason

    2018-01-01

    Planetariums are akin to “branch offices” for astronomy in major cities and other locations around the globe. With immersive, fulldome video technology, modern digital planetariums offer the opportunity to integrate authentic astronomical data into both pre-recorded shows and live lectures. At the California Academy of Sciences Morrison Planetarium, we host the monthly Benjamin Dean Astronomy Lecture Series, which features researchers describing their cutting-edge work to well-informed lay audiences. The Academy’s visualization studio and engineering teams work with researchers to visualize their data in both pre-rendered and real-time formats, and these visualizations are integrated into a variety of programs—including lectures! The assets are then made available to any other planetariums with similar software to support their programming. A lecturer can thus give the same immersive presentation to audiences in a variety of planetariums. The Academy has also collaborated with Chicago’s Adler Planetarium to bring Kavli Fulldome Lecture Series to San Francisco, and the two theaters have also linked together in live “domecasts” to share real-time content with audiences in both cities. These lecture series and other, similar projects suggest a bright future for astronomers to bring their research to the public in an immersive and visually compelling format.

  16. 156th Symposium of the International Astronomical Union

    CERN Document Server

    Kołaczek, Barbara

    1993-01-01

    In this review talk, I would like to report on the proper motion analysis, which has been recently carried out together with M. Soma and M. Yoshizawa: There has been a persistent demand in astronomy for accurate stellar positions and proper motions, which are represented by an inertial reference system constructed on the basis of a set of consistent astronomical constants. In the reference system the precessional constant plays a primary role. In a series of papers Fricke (1967a,b, 1977a,b) has deter­ mined the luni-solar precessional correction to Newcomb's value and the fictitious motion of the equinox, which have been adopted in the "IAU (1976) System of Astronomical Con­ stants". Based on the precessional correction and the equinoctial motion thus established, the fundamental reference system, the FK5 system (Fricke et al. 1988) for positions and proper motions, has been constructed. However, for several years geodetic VLBI (McCarthy & Luzum 1991) and LLR (Williams et at. 1991) observations have bee...

  17. Test facility for astronomical x-ray optics

    DEFF Research Database (Denmark)

    Christensen, Finn Erland; Lewis, Robert A.; Bordas, J.

    1990-01-01

    Grazing incidence x-ray optics for x-ray astronomical applications are used outside the earth's atmosphere. These devices require a large collection aperture and the imaging of an x-ray source that is essentially placed at infinity. The ideal testing system for these optical elements has to appro......Grazing incidence x-ray optics for x-ray astronomical applications are used outside the earth's atmosphere. These devices require a large collection aperture and the imaging of an x-ray source that is essentially placed at infinity. The ideal testing system for these optical elements has...... to approximate that encountered under working conditions; however, the testing of these optical elements is notoriously difficult with conventional x-ray generators. Synchrotron radiation (SR) sources are sufficiently brilliant to produce a nearly perfect parallel beam over a large area while still retaining...... a flux considerably higher than that available from conventional x-ray generators. A facility designed for the testing of x-ray optics, particularly in connection with x-ray telescopes, is described. It is proposed that this facility will be accommodated at the Synchrotron Radiation Source...

  18. Temperature control system for optical elements in astronomical instrumentation

    Science.gov (United States)

    Verducci, Orlando; de Oliveira, Antonio C.; Ribeiro, Flávio F.; Vital de Arruda, Márcio; Gneiding, Clemens D.; Fraga, Luciano

    2014-07-01

    Extremely low temperatures may damage the optical components assembled inside of an astronomical instrument due to the crack in the resin or glue used to attach lenses and mirrors. The environment, very cold and dry, in most of the astronomical observatories contributes to this problem. This paper describes the solution implemented at SOAR for remotely monitoring and controlling temperatures inside of a spectrograph, in order to prevent a possible damage of the optical parts. The system automatically switches on and off some heat dissipation elements, located near the optics, as the measured temperature reaches a trigger value. This value is set to a temperature at which the instrument is not operational to prevent malfunction and only to protect the optics. The software was developed with LabVIEWTM and based on an object-oriented design that offers flexibility and ease of maintenance. As result, the system is able to keep the internal temperature of the instrument above a chosen limit, except perhaps during the response time, due to inertia of the temperature. This inertia can be controlled and even avoided by choosing the correct amount of heat dissipation and location of the thermal elements. A log file records the measured temperature values by the system for operation analysis.

  19. Brazilian Participations in the International Astronomical Search Collaboration

    Science.gov (United States)

    Rojas, G. A.; Dalla-Costa, L. J.; Kalmus, A. T.; Kroth, E. C.; Matos, M. F.; Silva, A. L.; Silva, G. G.

    2014-10-01

    International Astronomical Search Collaboration (IASC) is an international educational project between universities, schools, observatories and research institutions. Its main objective is to enroll high school and college students in the monitoring and discovery of asteroids and Near Earth Objects (NEOs), especially Potentially Hazardous Asteroids. The methodology consists in the analysis of astronomical images obtained in several observatories in North America and Hawaii. The images are distributed throughout the school network and the results must be delivered in a 72-hour timeframe. Since 2010 Brazilian universities and schools have joined IASC, resulting in over a dozen new asteroids found (3 of them NEOs), and hundreds of measurements for already known asteroids. A major event in this collaboration was the All-Brazil Asteroid Search Campaign, which was conducted in September 2012. 2013 marks the fourth year of Brazilian participations in IASC, with one important milestone: the third straight appearance of a Brazilian institution in the Pan-STARRS campaign, which uses the PS1 telescope in Haleakala, Hawaii. We will present a summary of the overall results, as well as the latest news from 2013 campaigns. We will discuss the impact promoted by the past events, such as how the interest in astronomy changed before and after the campaigns, and it has helped the students to choose their future careers.

  20. The unforgotten sisters female astronomers and scientists before Caroline Herschel

    CERN Document Server

    Bernardi, Gabriella

    2016-01-01

    Taking inspiration from Siv Cedering’s poem in the form of a fictional letter from Caroline Herschel that refers to “my long, lost sisters, forgotten in the books that record our science”, this book tells the lives of twenty-five female scientists, with specific attention to astronomers and mathematicians. Each of the presented biographies is organized as a kind of "personal file" which sets the biographee’s life in its historical context, documents her main works, highlights some curious facts, and records citations about her. The selected figures are among the most representative of this neglected world, including such luminaries as Hypatia of Alexandra, Hildegard of Bingen, Elisabetha Hevelius, and Maria Gaetana Agnesi. They span a period of about 4000 years, from En HeduAnna, the Akkadian princess, who was one of the first recognized female astronomers, to the dawn of the era of modern astronomy with Caroline Herschel and Mary Somerville. The book will be of interest to all who wish to learn more ...

  1. Linear feature detection algorithm for astronomical surveys - I. Algorithm description

    Science.gov (United States)

    Bektešević, Dino; Vinković, Dejan

    2017-11-01

    Computer vision algorithms are powerful tools in astronomical image analyses, especially when automation of object detection and extraction is required. Modern object detection algorithms in astronomy are oriented towards detection of stars and galaxies, ignoring completely the detection of existing linear features. With the emergence of wide-field sky surveys, linear features attract scientific interest as possible trails of fast flybys of near-Earth asteroids and meteors. In this work, we describe a new linear feature detection algorithm designed specifically for implementation in big data astronomy. The algorithm combines a series of algorithmic steps that first remove other objects (stars and galaxies) from the image and then enhance the line to enable more efficient line detection with the Hough algorithm. The rate of false positives is greatly reduced thanks to a step that replaces possible line segments with rectangles and then compares lines fitted to the rectangles with the lines obtained directly from the image. The speed of the algorithm and its applicability in astronomical surveys are also discussed.

  2. Celestial delights the best astronomical events through 2020

    CERN Document Server

    Reddy, Francis

    2012-01-01

    Celestial Delights is the essential 'TV Guide' for the sky. Through extensive graphics integrated with an eight-year-long calendar of sky events, it provides a look at "don't miss" sky events, mostly for naked-eye and binocular observing. It is organized by ease of observation – lunar phases and the brighter planets come first, with solar eclipses, the aurora, and comets coming later. This third edition also includes a hefty dose of sky lore, astronomical history, and clear overviews of current science. It provides a handy reference to upcoming naked-eye events, with information broken out in clear and simple diagrams and tables that are cross-referenced against a detailed almanac for each year covered. This book puts a variety of information all in one place, presents it in a friendly way that does not require prior in-depth astronomical knowledge, and provides the context and historical background for understanding events that astronomy software or web sites lack.

  3. Weird astronomical theories of the solar system and beyond

    CERN Document Server

    Seargent, David

    2016-01-01

    After addressing strange cosmological hypotheses in Weird Universe, David Seargent tackles the no-less bizarre theories closer to home. Alternate views on the Solar System's formation, comet composition, and the evolution of life on Earth are only some of the topics he addresses in this new work. Although these ideas exist on the fringe of mainstream astronomy, they can still shed light on the origins of life and the evolution of the planets. Continuing the author's series of books popularizing strange astronomy facts and knowledge, Weird Astronomical Theories presents an approachable exploration of the still mysterious questions about the origin of comets, the pattern of mass extinctions on Earth, and more. The alternative theories discussed here do not come from untrained amateurs. The scientists whose work is covered includes the mid-20th century Russian S. K. Vsekhsvyatskii, cosmologist Max Tegmark, British astronomers Victor Clube and William Napier, and American Tom Van Flandern, a special...

  4. Explanatory Supplement to the Astronomical Almanac, Third Edition

    Science.gov (United States)

    Seidelmann, P. Kenneth; Urban, S. E.

    2010-01-01

    "The Explanatory Supplement to the Astronomical Almanac" (hereafter "The Explanatory Supplement") is a comprehensive reference book on the topic of positional astronomy, covering the theories and algorithms used to produce "The Astronomical Almanac" (AsA), an annual publication produced jointly by the Nautical Almanac Office of the US Naval Observatory (USNO) and Her Majesty's Nautical Almanac Office (HMNAO) of the UK Hydrographic Office. The first edition of The Explanatory Supplement appeared in 1961 and was reprinted with amendments during the 1970s. The second edition was printed in 1992 and reprinted until 2006. Since the second edition, several changes have taken place in positional astronomy regarding reference systems and internationally accepted models, data sets, and computational methods; these have been incorporated into the AsA. Additionally, the data presented in the AsA have been modified over the years, with new tables being added and some being discontinued. Given these changes, a new edition of The Explanatory Supplement is appropriate. The third edition has been in development for the last few years and will be available in 2010. The book is organized similarly to the second (1991) edition, with each chapter written by subject matter experts. Authors from USNO and HMNAO contributed to the majority of the book, but there are authors from Jet Propulsion Laboratory, Technical University of Dresden, National Geospatial-Intelligence Agency, University of Texas Austin, and University of Virginia. This paper will discuss this latest edition of the Explanatory Supplement.

  5. Astronomers Find World with Thick, Inhospitable Atmosphere and an Icy Heart

    Science.gov (United States)

    2009-12-01

    planets, they found that the observed radius exceeds the models' predictions: there is something more than the planet's solid surface blocking the star's light - a surrounding atmosphere, 200 km thick. "This atmosphere is much thicker than that of the Earth, so the high pressure and absence of light would rule out life as we know it," says Charbonneau, "but these conditions are still very interesting, as they could allow for some complex chemistry to take place." "Because the planet is too hot to have kept an atmosphere for long, GJ1214b represents the first opportunity to study a newly formed atmosphere enshrouding a world orbiting another star," adds team member Xavier Bonfils. "Because the planet is so close to us, it will be possible to study its atmosphere even with current facilities." The planet was first discovered as a transiting object within the MEarth project, which follows about 2000 low-mass stars to look for transits by exoplanets [4]. To confirm the planetary nature of GJ1214b and to obtain its mass (using the so-called Doppler method), the astronomers needed the full precision of the HARPS spectrograph, attached to ESO's 3.6-metre telescope at La Silla. An instrument with unrivalled stability and great precision, HARPS is the world's most successful hunter for small exoplanets. "This is the second super-Earth exoplanet for which the mass and radius could be obtained, allowing us to determine the density and to infer the inner structure," adds co-author Stephane Udry. "In both cases, data from HARPS was essential to characterise the planet." "The differences in composition between these two planets are relevant to the quest for habitable worlds," concludes Charbonneau. If super-Earth planets in general are surrounded by an atmosphere similar to that of GJ1214b, they may well be inhospitable to the development of life as we know it on our own planet. Notes [1] A super-Earth is defined as a planet between one and ten times the mass of the Earth. An exoplanet

  6. Astronomer's new guide to the galaxy: largest map of cold dust revealed

    Science.gov (United States)

    2009-07-01

    Astronomers have unveiled an unprecedented new atlas of the inner regions of the Milky Way, our home galaxy, peppered with thousands of previously undiscovered dense knots of cold cosmic dust -- the potential birthplaces of new stars. Made using observations from the APEX telescope in Chile, this survey is the largest map of cold dust so far, and will prove an invaluable map for observations made with the forthcoming ALMA telescope, as well as the recently launched ESA Herschel space telescope. ESO PR Photo 24a/09 View of the Galactic Plane from the ATLASGAL survey (annotated and in five sections) ESO PR Photo 24b/09 View of the Galactic Plane from the ATLASGAL survey (annotated) ESO PR Photo 24c/09 View of the Galactic Plane from the ATLASGAL survey (in five sections) ESO PR Photo 24d/09 View of the Galactic Plane from the ATLASGAL survey ESO PR Photo 24e/09 The Galactic Centre and Sagittarius B2 ESO PR Photo 24f/09 The NGC 6357 and NGC 6334 nebulae ESO PR Photo 24g/09 The RCW120 nebula ESO PR Video 24a/09 Annotated pan as seen by the ATLASGAL survey This new guide for astronomers, known as the APEX Telescope Large Area Survey of the Galaxy (ATLASGAL) shows the Milky Way in submillimetre-wavelength light (between infrared light and radio waves [1]). Images of the cosmos at these wavelengths are vital for studying the birthplaces of new stars and the structure of the crowded galactic core. "ATLASGAL gives us a new look at the Milky Way. Not only will it help us investigate how massive stars form, but it will also give us an overview of the larger-scale structure of our galaxy", said Frederic Schuller from the Max Planck Institute for Radio Astronomy, leader of the ATLASGAL team. The area of the new submillimetre map is approximately 95 square degrees, covering a very long and narrow strip along the galactic plane two degrees wide (four times the width of the full Moon) and over 40 degrees long. The 16 000 pixel-long map was made with the LABOCA submillimetre

  7. Astronomical calibration of the middle Eocene Contessa Highway section (Gubbio, Italy)

    Science.gov (United States)

    Jovane, Luigi; Sprovieri, Mario; Coccioni, Rodolfo; Florindo, Fabio; Marsili, Andrea; Laskar, Jacques

    2010-09-01

    The Eocene climatic system experienced an important transition from warm Paleocene greenhouse to icehouse Oligocene conditions. This transition could first appear as a long-term cooling trend but, at an up-close look, this period is a complex combination of climatic events and, for most of them, causes and consequences are still not fully characterized. In this context, a study has been carried out on the middle Eocene sedimentary succession of the Contessa Highway section, central Italy, which is proposed as the Global Stratotype Section and Point (GSSP) for the Lutetian/Bartonian boundary at the top of the Chron 19n, with an astronomically calibrated age of 41.23 Ma. Through a cyclostratigraphic analysis of the rhythmic sedimentary alternations and combination with the results of time series analysis of the proxy record, we provide an orbital tuning of the middle Eocene and astronomical calibration of the bio-magnetostratigraphic events (particularly for the C19n/C18r Chron boundary) recognized at the Contessa Highway section.

  8. Investigating Student Understanding of the Universe: Perceptions of Astronomical Sizes and Distances

    Science.gov (United States)

    Camarillo, Carmelita; Coble, K.; Hayes, V.; Nickerson, M.; Cochran, G. L.; Bailey, J. M.; McLin, K. M.; Cominsky, L. R.

    2011-05-01

    Student perceptions regarding astronomical sizes and distances are being analyzed for Chicago State University's Basic Astronomy course. This area is of great interest to further understand the students’ learning processes and to produce more effective instruction. Insights from cognitive psychology have shown that perceptions are related to prior experiences and current knowledge. Students enter into this course with different mental representations, and these representations can affect their learning. Through a repeated measures design, perceptions are analyzed through several instruments. The instruments implemented are pre-tests surveys (before lab), exams (after lab), lab comments, and interviews. Preliminary analysis reveals that students who have difficulty with astronomical sizes and distances have been more strongly influenced by culture and the media whereas those who had less difficulty expanded on their personal prior experiences. This project is part of a larger study; also see our posters on the structure of the universe, dark matter, the age and expansion of the universe. This work was supported by NASA ROSES E/PO Grant #NNXlOAC89G, as well as by the Illinois Space Grant Consortium and National Science Foundation CCLI Grant #0632563 at Chicago State University and the Fermi E/PO program at Sonoma State University.

  9. The Astronomical Sanctuary of the Celtiberian Town of Segeda (Mará, Zaragoza, Spain)

    Science.gov (United States)

    Burillo-Mozota, Francisco; Pérez-Gutiérrez, Manuel

    2015-05-01

    The Celtiberian town of Segeda (Mará, Zaragoza, Spain), with more than 45 ha of extension, was the largest pre-Roman settlement in the northern area of the Iberian Península (www.segeda.net). It was destroyed by the Roman army in 153 BC, a terminus ante quem for the construction of its peculiar sanctuary. The building was a large platform of about 312m2, bounded by two walls made up of large blocks of gypsum stone that converged in a strange angle of 120°. Its interior was paved and covered by sun-dried bricks, with no evidence of other outstanding structures. Its location, outside the city, next to the rampart and over a topographically prominent point, provided a privileged position because of the view it offered over its environment. The archaeoastronomical study started from a topographical survey by means of a topographic total station, complemented with a 360° photographic recording of the visible landscape and a measuring of the astronomical orientations. Several alignments of the platform with prominent points of the environment have been identified, arranged with the sunset at the summer solstice and the equinoxes. One of the sides of the structure is oriented with Astronomical North and a second one with the Minor Lunar Standstill, corresponding to the Metonic cycle.

  10. Urban light pollution - The effect of atmospheric aerosols on astronomical observations at night

    Science.gov (United States)

    Joseph, Joachim H.; Mekler, Yuri; Kaufman, Yoram J.

    1991-01-01

    The transfer of diffuse city light from a localized source through a dust-laden atmosphere with optical depth less than 0.5 has been analyzed in the source-observer plane on the basis of an approximate treatment. The effect on several types of astronomical observation at night has been studied, considering different size distributions and amounts as well as particle shapes of the aerosols. The analysis is made in terms of the signal-to-noise ratios for a given amount of aerosol. The model is applied to conditions at the Wise Astronomical Observatory in the Negev desert, and limiting backgrounds for spectroscopy, photometry, and photography of stars and extended objects have been calculated for a variety of signal-to-noise ratios. Applications to observations with different equipment at various distances from an urban area of any size are possible. Due to the use of signal-to-noise ratios, the conclusions are different for the different experimental techniques used in astronomy.

  11. Effect of rosuvastatin dose-loading on serum sLox-1, hs-CRP, and postoperative prognosis in diabetic patients with acute coronary syndromes undergoing selected percutaneous coronary intervention (PCI).

    Science.gov (United States)

    Jiao, Yungen; Hu, Feng; Zhang, Zhengang; Gong, Kaizheng; Sun, Xiaoning; Li, Aihua; Liu, Naifeng

    2015-01-01

    To investigate the effect of rosuvastatin dose-loading on serum levels of lectin-like oxidized low-density lipoprotein receptor-1 (Lox-1) and high-sensitivity c-reactive protein (hs-CRP) and postoperative prognosis in patients with diabetes and non-ST segment elevation acute coronary syndromes (NSTEACS) undergoing selected percutaneous coronary intervention (PCI). A total of 72 patients with diabetes and NSTEACS were randomized to either the group treated with 20 mg rosuvastatin 12 hours prior to PCI with a second dose administered just before PCI (n = 33), or a control group treated with standard method according guideline (n = 39). Serum levels of sLox-1, hs-CRP, CK-MB, and cTnI were measured prior to PCI, and at 24 hours and 30 days after PCI. The 30-day incidence of major adverse cardiac events (MACE) was recorded in both groups. Compared to pre-PCI, serum levels of sLox-1 and hs-CRP of the two groups were increased at 24 hours after PCI (P PCI (P PCI, the levels of TC and LDL-C were not changed at 24 hours after PCI (P > 0.05) until 30 days after PCI (P PCI; the 30-day incidence of MACE occurred in 6.06% of patients in the loading-dose rosuvastatin-treated group and in 23.08% of patients in the control-treated group (P PCI, and also reduce the occurrence of MACE 30 days after PCI.

  12. Astronomical Theory of Early Human Migration (Milutin Milankovic Medal Lecture)

    Science.gov (United States)

    Timmermann, Axel; Friedrich, Tobias

    2017-04-01

    Our climate system varies on a wide range of timescales, from seasons to several millions of years. A large part of this variability is internally generated as a result of instabilities of the coupled atmosphere-ocean-ice-carbon cycle system. Other modes of variability, such as glacial cycles, are caused by astronomical forcings with periods of 20, 40, 100 thousand years. These so-called Milankovitch Cycles are associated with earth's axis wobble, axis obliquity and shifts in the eccentricity of earth's orbit around the sun, respectively. When these cycles conspire, they can cause the climate system to plunge into an ice-age. This happened last time 110,000 years ago, when Northern Hemisphere summer radiation decreased substantially and ice-sheets started to form as a result. Around 100,000 years ago northern Hemisphere summer moved again closer to the sun and Homo sapiens started to leave Africa across vegetated corridors in Northeastern Africa and the Arabian Peninsula. This first migration wave must have been relatively weak, but it left unequivocal traces in the fossil and archaeological record. Why Homo sapiens embarked on its grand journey across our planet during glacial climate conditions has been subject of an intense debate in various scientific communities. Moreover, the archaeological records of an early exodus around 100 thousand years ago seem to be at odds with paleo-genetic evidences, that place the first dispersal out of Africa around 70-60 thousand years ago. To elucidate what role climate and environmental conditions played in the dispersal of Anatomically Modern Humans out of Africa, we have developed and applied one of the first integrated climate/human migration computer models. The model simulates ice-ages, abrupt climate change, the "peopling" of our planet and captures the arrival time of Homo sapiens in the Levant, Arabian Peninsula, Southern China and Australia in close agreement with paleo climate reconstructions, fossil and

  13. Terahertz Mixing Characteristics of NbN Superconducting Tunnel Junctions and Related Astronomical Observations

    Science.gov (United States)

    Li, J.

    2010-01-01

    High-sensitivity superconducting SIS (superconductor-insulator-superconductor) mixers are playing an increasingly important role in the terahertz (THz) astronomical observation, which is an emerging research frontier in modern astrophysics. Superconducting SIS mixers with niobium (Nb) tunnel junctions have reached a sensitivity close to the quantum limit, but have a frequency limit about 0.7 THz (i.e., gap frequency of Nb tunnel junctions). Beyond this frequency Nb superconducting films will absorb energetic photons (i.e., energy loss) to break Cooper pairs, thereby resulting in significant degradation of the mixer performance. Therefore, it is of particular interest to develop THz superconducting SIS mixers incorporating tunnel junctions with a larger energy gap. Niobium-nitride (NbN) superconducting tunnel junctions have been long known for their large energy gap, almost double that of Nb ones. With the introduction of epitaxially grown NbN films, the fabrication technology of NbN superconducting tunnel junctions has been considerably improved in the recent years. Nevertheless, their performances are still not as good as Nb ones, and furthermore they are not yet demonstrated in real astronomical applications. Given the facts mentioned above, in this paper we systematically study the quantum mixing behaviors of NbN superconducting tunnel junctions in the THz regime and demonstrate an astronomical testing observation with a 0.5 THz superconducting SIS mixer developed with NbN tunnel junctions. The main results of this study include: (1) successful design and fabrication of a 0.4˜0.6 THz waveguide mixing circuit with the high-dielectric-constant MgO substrate; (2) successful fabrication of NbN superconducting tunnel junctions with the gap voltage reaching 5.6 mV and the quality factor as high as 15; (3) demonstration of a 0.5 THz waveguide NbN superconducting SIS mixer with a measured receiver noise temperature (no correction) as low as five times the quantum limit

  14. Astronomers Make First Images With Space Radio Telescope

    Science.gov (United States)

    1997-07-01

    Marking an important new milestone in radio astronomy history, scientists at the National Radio Astronomy Observatory (NRAO) in Socorro, New Mexico, have made the first images using a radio telescope antenna in space. The images, more than a million times more detailed than those produced by the human eye, used the new Japanese HALCA satellite, working in conjunction with the National Science Foundation's (NSF) Very Long Baseline Array (VLBA) and Very Large Array (VLA) ground-based radio telescopes. The landmark images are the result of a long-term NRAO effort supported by the National Aeronautics and Space Administration (NASA). "This success means that our ability to make detailed radio images of objects in the universe is no longer limited by the size of the Earth," said NRAO Director Paul Vanden Bout. "Astronomy's vision has just become much sharper." HALCA, launched on Feb. 11 by Japan's Institute of Space and Astronautical Science (ISAS), is the first satellite designed for radio astronomy imaging. It is part of an international collaboration led by ISAS and backed by NRAO; Japan's National Astronomical Observatory; NASA's Jet Propulsion Laboratory (JPL); the Canadian Space Agency; the Australia Telescope National Facility; the European VLBI Network and the Joint Institute for Very Long Baseline Interferometry in Europe. On May 22, HALCA observed a distant active galaxy called PKS 1519-273, while the VLBA and VLA also observed it. Data from the satellite was received by a tracking station at the NRAO facility in Green Bank, West Virginia. Tape-recorded data from the satellite and from the radio telescopes on the ground were sent to NRAO's Array Operations Center (AOC) in Socorro, NM. In Socorro, astronomers and computer scientists used a special-purpose computer to digitally combine the signals from the satellite and the ground telescopes to make them all work together as a single, giant radio telescope. This dedicated machine, the VLBA Correlator, built as

  15. Education and Outreach Opportunities in New Astronomical Facilities

    Science.gov (United States)

    Mould, J. R.; Pompea, S.

    2002-12-01

    Astronomy presents extraordinary opportunities for engaging young people in science from an early age. The National Optical Astronomy Observatory (NOAO), supported by the National Science Foundation, leverages the attraction of astronomy with a suite of formal and informal education programs that engage our scientists and education and public outreach professionals in effective, strategic programs that capitalize on NOAO's role as a leader in science and in the design of new astronomical facilities. The core of the science education group at NOAO in Tucson consists of a group of Ph.D.-level scientists with experience in educational program management, curriculum and instructional materials development, teacher/scientist partnerships, and teacher professional development. This core group of scientist/educators hybrids has a strong background in earth and space science education as well as experience in working with and teaching about the technology that has enabled new astronomical discoveries. NOAO has a vigorous public affairs/media program and a history of effectively working locally, regionally, and nationally with the media, schools, science centers, and, planetaria. In particular, NOAO has created successful programs exploring how research data and tools can be used most effectively in the classroom. For example, the Teacher Leaders in Research Based Science Education explores how teachers can most effectively integrate astronomical research on novae, active galactic nuclei, and the Sun into classroom-based investigations. With immersive summer workshops at Kitt Peak National Observatory and the National Solar Observatory at Sacramento Peak, teachers learn research and instrumentation skills and how to encourage and maintain research activities in their classrooms. Some of the new facilities proposed in the recent decadal plan, Astronomy and Astrophysics in the New Millennium (National Academy Press), can provide extended opportunities for incorporating

  16. Astronomical Research with the MicroObservatory Net

    Science.gov (United States)

    Brecher, K.; Sadler, P.; Gould, R.; Leiker, S.; Antonucci, P.; Deutsch, F.

    1997-05-01

    We have developed a fully integrated automated astronomical telescope system which combines the imaging power of a cooled CCD, with a self-contained and weatherized 15 cm reflecting optical telescope and mount. The MicroObservatory Net consists of five of these telescopes. They are currently being deployed around the world at widely distributed longitudes. Remote access to the MicroObservatories over the Internet has now been implemented. Software for computer control, pointing, focusing, filter selection as well as pattern recognition have all been developed as part of the project. The telescopes can be controlled in real time or in delay mode, from a Macintosh, PC or other computer using Web-based software. The Internet address of the telescopes is http://cfa- www.harvard.edu/cfa/sed/MicroObservatory/MicroObservatory.html. In the real-time mode, individuals have access to all of the telescope control functions without the need for an `on-site' operator. Users can sign up for a specific period of ti me. In the batch mode, users can submit requests for delayed telescope observations. After a MicroObservatory completes a job, the user is automatically notified by e-mail that the image is available for viewing and downloading from the Web site. The telescopes were designed for classroom instruction, as well as for use by students and amateur astronomers for original scientific research projects. We are currently examining a variety of technical and educational questions about the use of the telescopes including: (1) What are the best approaches to scheduling real-time versus batch mode observations? (2) What criteria should be used for allocating telescope time? (3) With deployment of more than one telescope, is it advantageous for each telescope to be used for just one type of observation, i.e., some for photometric use, others for imaging? And (4) What are the most valuable applications of the MicroObservatories in astronomical research? Support for the Micro

  17. Scale Marking Method on the Circumference of Circle Elements for Astronomical Instruments in the Early Joseon Dynasty

    Directory of Open Access Journals (Sweden)

    Byeong-Hee Mihn

    2015-03-01

    Full Text Available During the reign of King Sejong (世宗, 1418-1450 in the Joseon Dynasty, there were lots of astronomical instruments, including miniaturized ones. Those instruments utilized the technical know-how acquired through building contemporary astronomical instruments previously developed in the Song(宋, Jin(金, and Yuan(元 dynasties of China. In those days, many astronomical instruments had circles, rings, and spheres carved with a scale of 365.25, 100, and 24 parts, respectively, on their circumference. These were called the celestial-circumference degree, hundred-interval (Baekgak, and 24 direction, respectively. These scales are marked by the angular distance, not by the angle. Therefore, these circles, rings, and spheres had to be optimized in size to accomodate proper scales. Assuming that the scale system is composed of integer multiples of unit length, we studied the sizes of circles by referring to old articles and investigating existing artifacts. We discovered that the star chart of Cheonsang yeolcha bunyajido was drawn with a royal standard ruler (周尺 based on the unit length of 207 mm. Interestingly, its circumference was marked by the unit scale of 3 puns per 1 du (or degree like Honsang (a celestial globe. We also found that Hyeonju ilgu (a equatorial sundial has a Baekgak disk on a scale of 1 pun per 1 gak (that is an interval of time similar to a quarter. This study contributes to the analysis of specifications of numerous circular elements from old Korean astronomical instruments.

  18. Radio Astronomers Set New Standard for Accurate Cosmic Distance Measurement

    Science.gov (United States)

    1999-06-01

    A team of radio astronomers has used the National Science Foundation's Very Long Baseline Array (VLBA) to make the most accurate measurement ever made of the distance to a faraway galaxy. Their direct measurement calls into question the precision of distance determinations made by other techniques, including those announced last week by a team using the Hubble Space Telescope. The radio astronomers measured a distance of 23.5 million light-years to a galaxy called NGC 4258 in Ursa Major. "Ours is a direct measurement, using geometry, and is independent of all other methods of determining cosmic distances," said Jim Herrnstein, of the National Radio Astronomy Observatory (NRAO) in Socorro, NM. The team says their measurement is accurate to within less than a million light-years, or four percent. The galaxy is also known as Messier 106 and is visible with amateur telescopes. Herrnstein, along with James Moran and Lincoln Greenhill of the Harvard- Smithsonian Center for Astrophysics; Phillip Diamond, of the Merlin radio telescope facility at Jodrell Bank and the University of Manchester in England; Makato Inoue and Naomasa Nakai of Japan's Nobeyama Radio Observatory; Mikato Miyoshi of Japan's National Astronomical Observatory; Christian Henkel of Germany's Max Planck Institute for Radio Astronomy; and Adam Riess of the University of California at Berkeley, announced their findings at the American Astronomical Society's meeting in Chicago. "This is an incredible achievement to measure the distance to another galaxy with this precision," said Miller Goss, NRAO's Director of VLA/VLBA Operations. "This is the first time such a great distance has been measured this accurately. It took painstaking work on the part of the observing team, and it took a radio telescope the size of the Earth -- the VLBA -- to make it possible," Goss said. "Astronomers have sought to determine the Hubble Constant, the rate of expansion of the universe, for decades. This will in turn lead to an

  19. High Energy Astronomical Data Processing and Analysis via the Internet

    Science.gov (United States)

    Valencic, Lynne A.; Snowden, S.; Pence, W.

    2012-01-01

    The HEASARC at NASA Goddard Space Flight Center and the US XMM-Newton GOF has developed Hera, a data processing facility for analyzing high energy astronomical data over the internet. Hera provides all the disk space and computing resources needed to do general processing of and advanced research on publicly available data from High Energy Astrophysics missions. The data and data products are kept on a server at GSFC and can be downloaded to a user's local machine. Further, the XMM-GOF has developed scripts to streamline XMM data reduction. These are available through Hera, and can also be downloaded to a user's local machine. These are free services provided to students, educators, and researchers for educational and research purposes.

  20. A Test Facility For Astronomical X-Ray Optics

    DEFF Research Database (Denmark)

    Lewis, R. A.; Bordas, J.; Christensen, Finn Erland

    1989-01-01

    Grazing incidence x-ray optics for x-ray astronomical applications are used outside the earths atmosphere. These devices require a large collection aperture and the imaging of an x-ray source which is essentially placed at infinity. The ideal testing system for these optical elements has...... to approximate that encountered under working conditions, however the testing of these optical elements is notoriously difficult with conventional x-ray generators. Synchrotron Radiation (SR) sources are sufficiently brilliant to produce a nearly perfect parallel beam over a large area whilst still retaining...... a flux considerably higher than that available from conventional x-ray generators. A facility designed for the testing of x-ray optics, particularly in connection with x-ray telescopes is described below. It is proposed that this facility will be accommodated at the Synchrotron Radiation Source...

  1. Progresos recientes en Astronomía de Rayos Gamma

    Science.gov (United States)

    Romero, G. E.

    Tras la exitosa misión del Compton Gamma-Ray Observatory durante los años 1990, la astronomía de rayos gamma ha entrado en una etapa de madurez, convirtiéndose en una de las principales herramientas para el estudio de procesos relativistas en el universo. En este reporte, presentaré una revisión de los principales tópicos abordados a través de estudios con rayos gamma en los últimos años, con particular énfasis en los intentos más recientes por establecer la naturaleza de las fuentes de rayos gamma no identificadas, detectadas por el instrumento EGRET.

  2. Global Vlasov simulation on magnetospheres of astronomical objects

    International Nuclear Information System (INIS)

    Umeda, Takayuki; Ito, Yosuke; Fukazawa, Keiichiro

    2013-01-01

    Space plasma is a collisionless, multi-scale, and highly nonlinear medium. There are various types of self-consistent computer simulations that treat space plasma according to various approximations. We develop numerical schemes for solving the Vlasov (collisionless Boltzmann) equation, which is the first-principle kinetic equation for collisionless plasma. The weak-scaling benchmark test shows that our parallel Vlasov code achieves a high performance and a high scalability. Currently, we use more than 1000 cores for parallel computations and apply the present parallel Vlasov code to various cross-scale processes in space plasma, such as a global simulation on the interaction between solar/stellar wind and magnetospheres of astronomical objects

  3. Laboratory spectrum of the PS radical and related astronomical search

    International Nuclear Information System (INIS)

    Ohishi, M.; Yamamoto, S.; Saito, S.; Kawaguchi, K.; Suzuki, H.

    1988-01-01

    The millimeter-wave rotational spectrum of the PS radical (X 2Pi r) was observed in the laboratory for the first time in the frequency region of 79-293 GHz by discharging the mixture of PSCl3 and He. Some 44 lines were measured, and the rotational constant, the centrifugal distortion constant, the centrifugal distortion term of the spin-orbit coupling constant, the Lambda-type doubling constants, and the hyperfine coupling constants were determined. Based on the measured and calculated frequencies, an astronomical search for the interstellar and circumstellar PS radical was made without success in Orion KL, Sgr B2, L134N,IRC + 10216, VY CMa, and OH 231.8 + 4.2. 29 references

  4. A List of Astronomical Meetings Available via Mosaic

    Science.gov (United States)

    Bryson, E.; Crabtree, D.

    We have been making a list of astronomical and related meetings available electronically for a number of years. Recently, several meeting organizers have made information about their meetings available via anonymous ftp or even NCSA Mosaic. We have produced a new version of our electronic meeting list available via NCSA Mosaic which provides links to the information being provided electronically. Depending upon the amount of information being provided for an individual meeting, it may be possible for a user browsing the list of meetings to click on the meeting of interest, fill out a registration form, download maps, browse abstracts, etc. We hope the availability of this service will encourage other meeting organizers to make information about their meetings available electronically and to take advantage of new technology such as NCSA Mosaic. URL: http:// cadcwww.dao.nrc.calmeetings/meetings.html

  5. Astronomy for older eyes a guide for aging backyard astronomers

    CERN Document Server

    Chen, James L

    2017-01-01

    This book is for the aging amateur astronomy population, including newcomers to astronomy in their retirement and hobbyists who loved peering through a telescope as a child. Whether a novice or an experienced observer, the practice of astronomy differs over the years. This guide will extend the enjoyment of astronomy well into the Golden Years by addressing topics such as eye and overall health issues, recommendations on telescope equipment, and astronomy-related social activities especially suited for seniors. Many Baby-Boomers reaching retirement age are seeking new activities, and amateur astronomy is a perfect fit as a leisure time activity. Established backyard astronomers who began their love of astronomy in their youth , meanwhile, may face many physical and mental challenges in continuing their lifelong hobby as they age beyond their 55th birthdays. That perfect telescope purchased when they were thirty years old now suddenly at sixty years old feels like an immovable object in the living room. The 20...

  6. An Overview of X-Ray Polarimetry of Astronomical Sources

    Directory of Open Access Journals (Sweden)

    Martin C. Weisskopf

    2018-03-01

    Full Text Available We review the history of astronomical X-ray polarimetry based on the author’s perspective, beginning with early sounding-rocket experiments by Robert Novick at Columbia University and his team, of which the author was a member. After describing various early techniques for measuring X-ray polarization, we discuss the polarimeter aboard the Orbiting Solar Observatory 8 (OSO-8 and its scientific results. Next, we describe the X-ray polarimeter to have flown aboard the ill-fated original Spectrum-X mission, which provided important lessons on polarimeter design, systematic effects, and the programmatics of a shared focal plane. We conclude with a description of the Imaging X-ray Polarimetry Explorer (IXPE and its prospective scientific return. IXPE, a partnership between NASA and ASI, has been selected as a NASA Astrophysics Small Explorers Mission and is currently scheduled to launch in April of 2021.

  7. Parsley: a Command-Line Parser for Astronomical Applications

    Science.gov (United States)

    Deich, William

    Parsley is a sophisticated keyword + value parser, packaged as a library of routines that offers an easy method for providing command-line arguments to programs. It makes it easy for the user to enter values, and it makes it easy for the programmer to collect and validate the user's entries. Parsley is tuned for astronomical applications: for example, dates entered in Julian, Modified Julian, calendar, or several other formats are all recognized without special effort by the user or by the programmer; angles can be entered using decimal degrees or dd:mm:ss; time-like intervals as decimal hours, hh:mm:ss, or a variety of other units. Vectors of data are accepted as readily as scalars.

  8. Survival Strategies for African American Astronomers and Astrophysicists

    Science.gov (United States)

    Holbrook, Jarita C.

    2012-08-01

    The question of how to increase the number of women and minorities in astronomy has been approached from several directions in the United States including examination of admission policies, mentoring, and hiring practices. These point to departmental efforts to improve conditions for some of the students which has the overall benefit of improving conditions for all of the students. However, women and minority astronomers have managed to obtain doctorates even within the non-welcoming environment of certain astronomy and physics departments. I present here six strategies used by African American men and women to persevere if not thrive long enough to earn their doctorate. Embedded in this analysis is the idea of `astronomy culture' and experiencing astronomy culture as a cross-cultural experience including elements of culture shock. These survival strategies are not exclusive to this small subpopulation but have been used by majority students, too.

  9. An Information Retrieval and Recommendation System for Astronomical Observatories

    Science.gov (United States)

    Mukund, Nikhil; Thakur, Saurabh; Abraham, Sheelu; Aniyan, A. K.; Mitra, Sanjit; Sajeeth Philip, Ninan; Vaghmare, Kaustubh; Acharjya, D. P.

    2018-03-01

    We present a machine-learning-based information retrieval system for astronomical observatories that tries to address user-defined queries related to an instrument. In the modern instrumentation scenario where heterogeneous systems and talents are simultaneously at work, the ability to supply people with the right information helps speed up the tasks for detector operation, maintenance, and upgradation. The proposed method analyzes existing documented efforts at the site to intelligently group related information to a query and to present it online to the user. The user in response can probe the suggested content and explore previously developed solutions or probable ways to address the present situation optimally. We demonstrate natural language-processing-backed knowledge rediscovery by making use of the open source logbook data from the Laser Interferometric Gravitational Observatory (LIGO). We implement and test a web application that incorporates the above idea for LIGO Livingston, LIGO Hanford, and Virgo observatories.

  10. Reducing the Requirements and Cost of Astronomical Telescopes

    Science.gov (United States)

    Smith, W. Scott; Whitakter, Ann F. (Technical Monitor)

    2002-01-01

    Limits on astronomical telescope apertures are being rapidly approached. These limits result from logistics, increasing complexity, and finally budgetary constraints. In an historical perspective, great strides have been made in the area of aperture, adaptive optics, wavefront sensors, detectors, stellar interferometers and image reconstruction. What will be the next advances? Emerging data analysis techniques based on communication theory holds the promise of yielding more information from observational data based on significant computer post-processing. This paper explores some of the current telescope limitations and ponders the possibilities increasing the yield of scientific data based on the migration computer post-processing techniques to higher dimensions. Some of these processes hold the promise of reducing the requirements on the basic telescope hardware making the next generation of instruments more affordable.

  11. The Associate Principal Astronomer for AI Management of Automatic Telescopes

    Science.gov (United States)

    Henry, Gregory W.

    1998-01-01

    This research program in scheduling and management of automatic telescopes had the following objectives: 1. To field test the 1993 Automatic Telescope Instruction Set (ATIS93) programming language, which was specifically developed to allow real-time control of an automatic telescope via an artificial intelligence scheduler running on a remote computer. 2. To develop and test the procedures for two-way communication between a telescope controller and remote scheduler via the Internet. 3. To test various concepts in Al scheduling being developed at NASA Ames Research Center on an automatic telescope operated by Tennessee State University at the Fairborn Observatory site in southern Arizona. and 4. To develop a prototype software package, dubbed the Associate Principal Astronomer, for the efficient scheduling and management of automatic telescopes.

  12. The Undergraduate Research Resources at the Pisgah Astronomical Research Institute

    Science.gov (United States)

    Cline, J. Donald; Castelaz, Michael W.

    2016-01-01

    Pisgah Astronomical Research Institute (PARI), a former NASA tracking station located in western North Carolina, has been offering programs, campus, and instrument use for undergraduate research and learning experiences since 2000. Over these years, PARI has collaborated with universities and colleges in the Southeastern U.S. Sharing its campus with institutions of higher learning is a priority for PARI as part of its mission to "to providing hands-on educational and research opportunities for a broad cross-section of users in science, technology, engineering and math (STEM) disciplines."PARI is a 200 acre campus for environmental, earth, geological, physical, and astronomical sciences. For example, the PARI 26-m and 4.6-m radio telescopes are excellent for teaching electromagnetic theory, spectroscopy, atomic and molecular emission processes, and general physics and astronomy concepts. The PARI campus has lab and office space, data centers with high speed internet, distance learning capabilities, radio and optical telescopes, earth science sensors, housing and cafeteria.Also, the campus is in an excellent spot for environmental and biological sciences lab and classroom experiences for students. The campus has the capability to put power and Internet access almost anywhere on its 200 acre campus so experiments can be set up in a protected area of a national forest. For example, Earthscope operates a Plate Boundary Observatory sensor on campus to measure plate tectonic motion. And, Clemson University has an instrument measuring winds and temperatures in the Thermsophere. The use of thePARI campus is limited only by the creativity faculty to provide a rich educational environment for their students. An overview of PARI will be presented along with a summary of programs, and a summary of undergraduate research experiences over the past 15 years. Access to PARI and collaboration possibilities will be presented.

  13. Properties of galactic dark matter: Constraints from astronomical observations

    International Nuclear Information System (INIS)

    Burch, B.; Cowsik, R.

    2013-01-01

    The distributions of normal matter and of dark matter in the Galaxy are coupled to each other as they both move in the common gravitational potential. In order to fully exploit this interplay and to derive the various properties of dark matter relevant to their direct and indirect detection, we have comprehensively reviewed the astronomical observations of the spatial and velocity distributions of the components of normal matter. We then postulate that the phase-space distribution of dark matter follows a lowered-isothermal form and self-consistently solve Poisson's equation to construct several models for the spatial and velocity distributions of dark matter. In this paper, we compute the total gravitational potential of the normal and dark matter components and investigate their consistency with current observations of the rotation curve of the Galaxy and of the spatial and velocity distributions of blue horizontal-branch and blue straggler stars. Even with this demand of consistency, a large number of models with a range of parameters characterizing the dark matter distribution remain. We find that the best choice of parameters, within the range of allowed values for the surface density of the disk 55 M ☉ pc –2 , are the following: the dark matter density at the Galactic center ρ DM, c ≈ 100-250 GeV cm –3 , the local dark matter density ρ DM (R 0 ) ≈ 0.56-0.72 GeV cm –3 , and the rms speed of dark matter particles 〈v DM 2 (R 0 )〉 1/2 ≈490−−550 km s –1 . We also discuss possible astronomical observations that may further limit the range of the allowed models. The predictions of the allowed models for direct and indirect detection will be discussed separately in a companion paper.

  14. Astronomical and Meteorological Conditions of a Solar System Operation

    Science.gov (United States)

    Proszak-Miąsik, Danuta; Bukowska, Maria; Nowak, Krzysztof; Rabczak, Sławomir

    2017-10-01

    Acquisition and processing of as much solar energy for heating and electricity generation in Poland and in the world is a very important objective in the policy of alternative energy sources. The main problem with the reception of solar energy by solar collectors is vary energy supply at different times of day and year and low flux density of radiation. The term of solar radiation one mean transmission or emission of energy in the form of electromagnetic waves. The radiation emitted from the surface of the sun spreads out in all directions in space, reaches the Earth’s surface in only partly, especially the solar collectors. The most important parameters characterizing solar radiation are daily, monthly and annual sum of solar radiation. Its express the amount of solar energy which falls on a unit area at a given time. Number of hours of sunshine during the day are dependent on two key factors. The first one is the time from the sunrise to sunset, which strongly depends on the date and latitude. The second factor is the weather (clouds), influences solar radiation, radiation in touch with clouds is absorbed and dissipated. This publication shows the impact on the energy yield of the flat collector installation and astronomical conditions (angle of inclination and declination of solar), and climate. The calculations of determining the astronomical conditions of the place where the installation is located ware analyzed. The solar installation is located in Rzeszow (Poland) and the plate collector placed on the roof of building. Based on specific methodology for selected days the calculation of the elevation angle of the Sun, hourly angle, the sun azimuth and angle of incidence of the radiation on any plane were set. The results are shown in diagrams. The effect of cloud cover on the acquisition of solar energy by the collector is also shown.

  15. The application of artificial intelligence to astronomical scheduling problems

    Science.gov (United States)

    Johnston, Mark D.

    1992-01-01

    Efficient utilization of expensive space- and ground-based observatories is an important goal for the astronomical community; the cost of modern observing facilities is enormous, and the available observing time is much less than the demand from astronomers around the world. The complexity and variety of scheduling constraints and goals has led several groups to investigate how artificial intelligence (AI) techniques might help solve these kinds of problems. The earliest and most successful of these projects was started at Space Telescope Science Institute in 1987 and has led to the development of the Spike scheduling system to support the scheduling of Hubble Space Telescope (HST). The aim of Spike at STScI is to allocate observations to timescales of days to a week observing all scheduling constraints and maximizing preferences that help ensure that observations are made at optimal times. Spike has been in use operationally for HST since shortly after the observatory was launched in Apr. 1990. Although developed specifically for HST scheduling, Spike was carefully designed to provide a general framework for similar (activity-based) scheduling problems. In particular, the tasks to be scheduled are defined in the system in general terms, and no assumptions about the scheduling timescale are built in. The mechanisms for describing, combining, and propagating temporal and other constraints and preferences are quite general. The success of this approach has been demonstrated by the application of Spike to the scheduling of other satellite observatories: changes to the system are required only in the specific constraints that apply, and not in the framework itself. In particular, the Spike framework is sufficiently flexible to handle both long-term and short-term scheduling, on timescales of years down to minutes or less. This talk will discuss recent progress made in scheduling search techniques, the lessons learned from early HST operations, the application of Spike

  16. Astronomers Get Closest Look Yet At Milky Way's Mysterious Core

    Science.gov (United States)

    2005-11-01

    Astronomers have gotten their deepest glimpse into the heart of our Milky Way Galaxy, peering closer to the supermassive black hole at the Galaxy's core then ever before. Using the National Science Foundation's continent-wide Very Long Baseline Array (VLBA), they found that a radio-wave-emitting object at the Galaxy's center would nearly fit between the Earth and the Sun. This is half the size measured in any previous observation. "We're getting tantalizingly close to being able to see an unmistakable signature that would provide the first concrete proof of a supermassive black hole at a galaxy's center," said Zhi-Qiang Shen, of the Shanghai Astronomical Observatory and the Chinese Academy of Sciences. A black hole is a concentration of mass so dense that not even light can escape its powerful gravitational pull. Milky Way Nucleus The Milky Way's nucleus, as seen with the VLA. Sagittarius A* is the bright white dot at center. CREDIT: NRAO/AUI/NSF, Jun-Hui Zhao, W.M. Goss (Click on Image for Larger Version) The astronomers used the VLBA to measure the size of an object called Sagittarius A* (pronounced "A-star") that marks the exact center of our Galaxy. Last year, a different team announced that their measurements showed the object would fit inside the complete circle of Earth's orbit around the Sun. Shen and his team, by observing at a higher radio frequency, measured Sagittarius A* as half that size. A mass equal to four million Suns is known to lie within Sagittarius A*, and the new measurement makes the case for a black hole even more compelling than it was previously. Scientists simply don't know of any long-lasting object other than a black hole that could contain this much mass in such a small area. However, they would like to see even stronger proof of a black hole. "The extremely strong gravitational pull of a black hole has several effects that would produce a distinctive 'shadow' that we think we could see if we can image details about half as small as

  17. A Reappraising of Cosmography: the Interface Between Astronomical and Geographic Studies. (Breton Title: Releitura do Conceito de Cosmografia: a Interface Entre os Estudos Astronômicos e Geográficos.) Una Relectura del Concepto de Cosmografía: la Interfase Entre los Estudios Astronómicos y Geográficos

    Science.gov (United States)

    Azevedo Sobreira, Paulo Henrique

    2012-12-01

    The concept of "Cosmography" is in disuse since the 80s of the last century, but the astronomical themes previously discussed in the school subjects of Geography and Cosmography remain in current textbooks. The use of term "Cosmography" was rescued in this research, and the study of its re-signification prompted the appearance of the term Geographic Cosmography. The Geographic Cosmography is a field of studies of the Geography, whose set of knowledge and skills is predominantly scholar. It studies the interface between terrestrial and celestial knowledge, and assigns a geographic significance to them. It examines human and natural relationships with Sidereal Space and its consequences for society and nature. O conceito de "Cosmografia" está em desuso desde os anos 80 do século XX, mas os temas astronômicos anteriormente abordados nas disciplinas escolares de Cosmografia e de Geografia permanecem nos atuais livros didáticos. O uso do termo "Cosmografia" foi resgatado nesta pesquisa e o estudo de sua ressignificação proporcionou o surgimento do termo Cosmografia Geográfica. A Cosmografia Geográfica é um campo de estudos da Geografia, cujo conjunto de conhecimentos e habilidades é predominantemente escolar. Estuda a interface entre os conhecimentos terrestres e os celestes e lhes atribui significância geográfica. Analisa as relações humanas e naturais com o Espaço Sideral e suas consequências para a sociedade e a natureza. Aunque el concepto de "Cosmografía" no se usa desde la década de los '80 del siglo pasado, los temas astronómicos que se enseñaban anteriormente en las asignaturas escolares de Cosmografía y de Geografía permanecen en los actuales libros didácticos. El uso del término "Cosmografía" fue rescatado en esta investigación y el estudio de su resignificación proporcionó el surgimiento del término Cosmografía Geográfica. La Cosmografía Geográfica es un campo de estudio de la Geografía, donde el conjunto de conocimientos y

  18. Preserving Astronomy's Photographic Legacy: Current State and the Future of North American Astronomical Plates

    Science.gov (United States)

    Osborn, W.; Robbins, L.

    2009-08-01

    This book contains articles on preserving astronomy's valuable heritage of photographic observations, most of which are on glass plates. It is intended to serve as a reference for institutions charged with preserving and managing plate archives and astronomers interested in using archival photographic plates in their research. The first portion of the book focuses on previous activities and recommendations related to plate archiving. These include actions taken by the International Astronomical Union, activities in Europe and a detailed account of a workshop on preserving astronomical photographic data held in 2007 at the Pisgah Astronomical Research Institute, North Carolina. The workshop discussions covered a wide range of issues that must be considered in any effort to archive plates and culminated in a set of recommendations on preserving, cataloging and making publicly available these irreplaceable data. The second part of the book reports on some recent efforts to implement the recommendations. These include essays on the recently established Astronomical Photographic Data Archive, projects to make photographic collections available electronically, evaluations of commercial scanners for digitization of astronomical plates and the case for the continuing value of these data along with a report on the census of astronomical plate collections in North America carried out in 2008. The census cataloged the locations, numbers, and types of astronomical plates in the US and Canada. Comprehensive appendices identify all the significant collections in North America and detail the current contents, state and status of their holdings.

  19. ``Orion, I Don't Love You'': The Astronomical Legacy of Carl Sandburg

    Science.gov (United States)

    Ricca, B.

    2013-04-01

    Can poetry provide an accurate means of representing the scientific universe? This paper looks at the astronomical poetry of Carl Sandburg and how the poet employs a scientific framework to deepen his work. Sandburg's method is then compared to a class project of middle school students who use his poetry (and their own) to learn and understand astronomical facts.

  20. Support for the Astronomically Calibrated 40Ar/39Ar Age of Fish Canyon Sanidine

    DEFF Research Database (Denmark)

    Rivera, Tiffany; Storey, Michael; Zeeden, Christian

    2011-01-01

    al. (2008) determined an astronomically calibrated 40Ar/39Ar age of 28.201 0.046 Ma (2), relative to the indirect astronomically tuned Moroccan Melilla Basin Messâdit section. Here, we provide independent verification for the Kuiper, et al. (2008) FCs age using sanidines extracted from the A1 tephra...

  1. THE INFRARED SPECTRA OF VERY LARGE IRREGULAR POLYCYCLIC AROMATIC HYDROCARBONS (PAHs): OBSERVATIONAL PROBES OF ASTRONOMICAL PAH GEOMETRY, SIZE, AND CHARGE

    International Nuclear Information System (INIS)

    Bauschlicher, Charles W.; Peeters, Els; Allamandola, Louis J.

    2009-01-01

    The mid-infrared (IR) spectra of six large, irregular polycyclic aromatic hydrocarbons (PAHs) with formulae (C 84 H 24 -C 120 H 36 ) have been computed using density functional theory (DFT). Trends in the dominant band positions and intensities are compared to those of large, compact PAHs as a function of geometry, size, and charge. Irregular edge moieties that are common in terrestrial PAHs, such as bay regions and rings with quartet hydrogens, are shown to be uncommon in astronomical PAHs. As for all PAHs comprised solely of C and H reported to date, mid-IR emission from irregular PAHs fails to produce a strong CC str band at 6.2 μm, the position characteristic of the important, class A astronomical PAH spectra. Earlier studies showed that inclusion of nitrogen within a PAH shifts this to 6.2 μm for PAH cations. Here we show that this band shifts to 6.3 μm in nitrogenated PAH anions, close to the position of the CC stretch in class B astronomical PAH spectra. Thus, nitrogenated PAHs may be important in all sources and the peak position of the CC stretch near 6.2 μm appears to directly reflect the PAH cation to anion ratio. Large irregular PAHs exhibit features at 7.8 μm but lack them near 8.6 μm. Hence, the 7.7 μm astronomical feature is produced by a mixture of small and large PAHs while the 8.6 μm band can only be produced by large compact PAHs. As with the CC str , the position and profile of these bands reflect the PAH cation to anion ratio.

  2. Cooperation for Common Use of SEE Astronomical Database as a Regional Virtual Observatory in Different Scientific Projects

    Science.gov (United States)

    Pinigin, Gennady; Protsyuk, Yuri; Shulga, Alexander

    The activity of scientific collaborative and co-operative research between South-Eastern European (SEE) observatories is enlarged in the last time. The creation of a common database as a regional virtual observatory is very desirable. The creation of astronomical information resource with a capability of interactive access to databases and telescopes on the base of the general astronomical database of the SEE countries is presented. This resource may be connected with the European network. A short description of the NAO database is presented. The total amount of the NAO information makes about 90 GB, the one obtained from other sources - about 15 GB. The mean diurnal level of the new astronomical information produced with the NAO CCD instruments makes from 300 MB up to 2 GB, depending on the purposes and conditions of observations. The majority of observational data is stored in FITS format. Possibility of using of VO-table format for displaying these data in the Internet is studied. Activities on development and the further refinement of storage, exchange and data processing standards are conducted.

  3. Chemometric technique for the optimization of chromatographic system: Simultaneous HPLC determination of Rosuvastatin, Telmisartan, Ezetimibe and Atorvastatin used in combined cardiovascular therapy

    Directory of Open Access Journals (Sweden)

    V. Sree Janardhanan

    2016-11-01

    Full Text Available Developed and optimized a validated isocratic reverse phase HPLC separation of Rosuvastatin, Telmisartan, Ezetimibe and Atorvastatin in pharmaceutical preparation using response surface methodology. The separation was carried out by using phenomenex C18 column (15 cm × 4.6 mm id, 5 μm particle size and UV detection at 239 nm. The ranges of the independent variables used for the optimization were MeCN: 33–38%, buffer conc.: 10–20 mM and flow rate: 1–2 ml/min. The influence of these independent variables on the output responses: capacity factor of the first peak (k1, resolutions of the 2nd and 3rd peak (Rs2,3, and capacity factor of the fifth peak (k5 were evaluated. Using this strategy, a mathematical model was defined and a response surface was derived for the separation. The three responses were simultaneously optimized by using Derringer's desirability functions. Optimum conditions chosen for the assay were MeCN, MeOH, 20 mM K2HPO4 (pH 3.0 ± 0.2 solution (34.27:20:45.73 v/v/v and flow rate 2 ml/min. Total chromatographic analysis time per sample was approximately 10 min. The optimized assay condition was validated as per the ICH guidelines and applied for the quantitative analysis of Rosavel EZ, Avas-EZ and Lipisar 20 tablet. The developed method was simple, accurate and precise. Hence, it can be employed for the routine analysis in quality control laboratories.

  4. Ticking Stellar Time Bomb Identified - Astronomers find prime suspect for a Type Ia supernova

    Science.gov (United States)

    2009-11-01

    Using ESO's Very Large Telescope and its ability to obtain images as sharp as if taken from space, astronomers have made the first time-lapse movie of a rather unusual shell ejected by a "vampire star", which in November 2000 underwent an outburst after gulping down part of its companion's matter. This enabled astronomers to determine the distance and intrinsic brightness of the outbursting object. It appears that this double star system is a prime candidate to be one of the long-sought progenitors of the exploding stars known as Type Ia supernovae, critical for studies of dark energy. "One of the major problems in modern astrophysics is the fact that we still do not know exactly what kinds of stellar system explode as a Type Ia supernova," says Patrick Woudt, from the University of Cape Town and lead author of the paper reporting the results. "As these supernovae play a crucial role in showing that the Universe's expansion is currently accelerating, pushed by a mysterious dark energy, it is rather embarrassing." The astronomers studied the object known as V445 in the constellation of Puppis ("the Stern") in great detail. V445 Puppis is the first, and so far only, nova showing no evidence at all for hydrogen. It provides the first evidence for an outburst on the surface of a white dwarf [1] dominated by helium. "This is critical, as we know that Type Ia supernovae lack hydrogen," says co-author Danny Steeghs, from the University of Warwick, UK, "and the companion star in V445 Pup fits this nicely by also lacking hydrogen, instead dumping mainly helium gas onto the white dwarf." In November 2000, this system underwent a nova outburst, becoming 250 times brighter than before and ejecting a large quantity of matter into space. The team of astronomers used the NACO adaptive optics instrument [2] on ESO's Very Large Telescope (VLT) to obtain very sharp images of V445 Puppis over a time span of two years. The images show a bipolar shell, initially with a very narrow

  5. What makes astronomical heritage valuable? Identifying potential Outstanding Universal Value in cultural properties relating to astronomy

    Science.gov (United States)

    Cotte, Michel

    2016-10-01

    This communication presents the situation regarding astronomical and archaeoastronomical heritage related to the World Heritage Convention through recent years up until today. Some parallel events and works were promoted strongly within the IAU-UNESCO Initiative during the International Year of Astronomy (2009). This was followed by a joint program by the IAU and ICOMOS-an official advisory body assisting the World Heritage Committee in the evaluation of nomination dossiers. The result of that work is an important publication by around 40 authors from 20 different countries all around the world: Heritage Sites of Astronomy and Archaeoastronomy in the Context of the UNESCO World Heritage Convention (Ruggles & Cotte 2010). A second volume is under preparation (2015). It was also accompanied by some initiatives such as the ``Windows to the Universe" organisation and the parallel constitution of local ``Starlight Reserves''. Some regional meetings studying specific facets or regional heritage in the field giving significant knowledge progresses also accompanied the global trend for astronomical heritage. WH assessment is defined by a relatively strict format and methodology. A key phrase is ``demonstration of Outstanding Universal Value'' to justify the WH Listing by the Committee. This communication first examines the requirements and evaluation practices about of demonstrating OUV for a given place in the context of astronomical or archaeoastronomical heritage. That means the examination of the tangible attributes, an inventory of the property in terms of immoveable and moveable components and an inventory of intangible issues related to the history (history of the place in the context of the history of astronomy and cultural history). This is also related to the application to the site of the concept of integrity and authenticity, as regards the place itself and in comparison with other similar places (WH sites already listed, sites on national WH Tentative Lists

  6. Astronomical Instruments with Two Scales Drawn on Their Common Circumference of Rings in the Joseon Dynasty

    Directory of Open Access Journals (Sweden)

    Byeong-Hee Mihn

    2017-03-01

    Full Text Available This study examines the scale unique instruments used for astronomical observation during the Joseon dynasty. The Small Simplified Armillary Sphere (小簡儀, So-ganui and the Sun-and-Stars Time-Determining Instrument (日星定時儀, Ilseong-jeongsi-ui are minimized astronomical instruments, which can be characterized, respectively, as an observational instrument and a clock, and were influenced by the Simplified Armilla (簡儀, Jianyi of the Yuan dynasty. These two instruments were equipped with several rings, and the rings of one were similar both in size and in scale to those of the other. Using the classic method of drawing the scale on the circumference of a ring, we analyze the scales of the Small Simplified Armillary Sphere and the Sun-and-Stars Time-Determining Instrument. Like the scale feature of the Simplified Armilla, we find that these two instruments selected the specific circumference which can be drawn by two kinds of scales. If Joseon’s astronomical instruments is applied by the dual scale drawing on one circumference, we suggest that 3.14 was used as the ratio of the circumference of circle, not 3 like China, when the ring’s size was calculated in that time. From the size of Hundred-interval disk of the extant Simplified Sundial in Korea, we make a conclusion that the three rings’ diameter of the Sun-and-Stars Time-Determining Instrument described in the Sejiong Sillok (世宗實錄, Veritable Records of the King Sejong refers to that of the middle circle of every ring, not the outer circle. As analyzing the degree of 28 lunar lodges (lunar mansions in the equator written by Chiljeongsan-naepyeon (七政算內篇, the Inner Volume of Calculation of the Motions of the Seven Celestial Determinants, we also obtain the result that the scale of the Celestial-circumference-degree in the Small Simplified Armillary Sphere was made with a scale error about 0.1 du in root mean square (RMS.

  7. Astronomical Instruments with Two Scales Drawn on Their Common Circumference of Rings in the Joseon Dynasty

    Science.gov (United States)

    Mihn, Byeong-Hee; Choi, Goeun; Lee, Yong Sam

    2017-03-01

    This study examines the scale unique instruments used for astronomical observation during the Joseon dynasty. The Small Simplified Armillary Sphere (小簡儀, So-ganui) and the Sun-and-Stars Time-Determining Instrument (日星定時儀, Ilseong-jeongsi-ui) are minimized astronomical instruments, which can be characterized, respectively, as an observational instrument and a clock, and were influenced by the Simplified Armilla (簡儀, Jianyi) of the Yuan dynasty. These two instruments were equipped with several rings, and the rings of one were similar both in size and in scale to those of the other. Using the classic method of drawing the scale on the circumference of a ring, we analyze the scales of the Small Simplified Armillary Sphere and the Sun-and-Stars Time-Determining Instrument. Like the scale feature of the Simplified Armilla, we find that these two instruments selected the specific circumference which can be drawn by two kinds of scales. If Joseon`s astronomical instruments is applied by the dual scale drawing on one circumference, we suggest that 3.14 was used as the ratio of the circumference of circle, not 3 like China, when the ring`s size was calculated in that time. From the size of Hundred-interval disk of the extant Simplified Sundial in Korea, we make a conclusion that the three rings` diameter of the Sun-and-Stars Time-Determining Instrument described in the Sejiong Sillok (世宗實錄, Veritable Records of the King Sejong) refers to that of the middle circle of every ring, not the outer circle. As analyzing the degree of 28 lunar lodges (lunar mansions) in the equator written by Chiljeongsan-naepyeon (七政算內篇, the Inner Volume of Calculation of the Motions of the Seven Celestial Determinants), we also obtain the result that the scale of the Celestial-circumference-degree in the Small Simplified Armillary Sphere was made with a scale error about 0.1 du in root mean square (RMS).

  8. Astronomers Take the Measure of Dark Matter in the universe

    Science.gov (United States)

    2001-09-01

    Using NASA's Chandra X-ray Observatory, astronomers have obtained their most accurate determination to date of the amount of dark matter in galaxy clusters, the most massive objects in the universe. The results provide an important step towards a precise measurement of the total matter density of the universe. These results were presented today by Steven W. Allen of the Institute of Astronomy in Cambridge, UK at a press conference at the `Two Years of Science with Chandra' symposium in Washington, DC. Allen and his colleagues Robert W. Schmidt and Andrew C. Fabian at the Institute of Astronomy observed a carefully chosen sample of five of the largest clusters of galaxies known, whose distances range from 1.5 to 4 billion light years. The team made temperature maps of the hot multimillion-degree gas that fills the clusters. "The temperature maps can be used to determine the mass needed to prevent the hot gas from escaping the clusters" explained Allen. "We found that the stars in the galaxies and hot gas together contribute only about 13 percent of the mass. The rest must be in the form of dark matter." The nature of the dark matter is not known, but most astronomers think that it is in the form of an as yet unknown type of elementary particle that contributes to gravity through its mass but otherwise interacts weakly with normal matter. These dark matter particles are often called WIMPs, an acronym for `weakly interacting massive particles'. Clusters of galaxies are vast concentrations of galaxies, hot gas and dark matter spanning millions of light years, held together by gravity. Because of their size, clusters of galaxies are thought to provide a fair sample of the proportion of dark matter in the universe as a whole. "The implication of our results is that we live in a low-density universe" said Allen. "The total mass-density is only about thirty percent of that needed to stop the universe from expanding forever." The result reinforces recent findings from

  9. Denver's Pioneer Astronomer: Herbert Alonso Howe (1858-1926)

    Science.gov (United States)

    Howe, H. J.; Stencel, R. E.; Fisher, S.

    1999-05-01

    Herbert A. Howe arrived at Denver University (DU) to teach autumn 1880 classes, in math, astronomy and surveying. Howe established himself with clever solutions to the Kepler problem for orbit determinations in thesis work at Cincinnati Observatory. Riding the economic expansion of Colorado gold and silver mining in 1888, the University accepted a proposed gift of a major observatory, offered by Denver real estate baron, Humphrey Chamberlin. The result features a 20 inch aperture Alvan Clark refractor, which still ranks among the largest telescopes of the era. With the observatory building ready, the Silver Panic of 1893 -- when the US Congress dropped silver reserves from the currency basis -- burst the Denver economic bubble. Chamberlin was unable to complete payments on the balances due. Clark and G.N.Saegmuller (Fauth and Co.) at personal expense, delivered on the optics and telescope assemblies in 1894, but would wait for repayment. Sadly, this fiscal crisis affected DU for over a decade. Professor Howe, while observatory director, found himself consumed as Dean and Acting Chancellor for a young, struggling university, at the expense of the astronomy future that had looked so bright in 1892. Absent the Silver Panic, Howe would have probably been given an endowed chair in astronomy, as promised by Chamberlin. The complexion of American astronomy at the time of the birth of the American Astronomical Society in 1899 might have been different, in terms of US observing sites, etc. We are fortunate to have extensive Prof.Howe's daily diaries now in the University archives. These describe Howe's view of progress on the observatory, meetings with astronomy notables, plus vignettes of the life and times of Denver and the nation. Grandson, Herbert Julian Howe rediscovered their existence and is summarizing them in the form of a biography entitled: The Pioneer Astronomer. DU archival records contain numerous original letters from late 19th century astronomy luminaries

  10. Astronomical tunings of the Oligocene-Miocene transition from Pacific Ocean Site U1334 and implications for the carbon cycle

    NARCIS (Netherlands)

    Beddow, Helen M.; Liebrand, Diederik; Wilson, Douglas S.; Hilgen, Frits J.; Sluijs, Appy; Wade, Bridget S.; Lourens, Lucas J.

    2018-01-01

    Astronomical tuning of sediment sequences requires both unambiguous cycle pattern recognition in climate proxy records and astronomical solutions, as well as independent information about the phase relationship between these two. Here we present two different astronomically tuned age models for the

  11. An anchored astronomical time-scale for the Turonian reference sections in the Umbria-Marche Basin, Italy

    Science.gov (United States)

    De Vleeschouwer, D.; Montanari, A.; Coccioni, R.

    2012-04-01

    In the Umbria-Marche basin, the aftermath of Ocean Anoxic Event 2 (OAE2, Bonarelli Level) is represented by the Turonian part of the Scaglia Rossa Formation. The Scaglia Rossa pelagic limestones were studied in the classic Contessa and Bottaccione sections near Gubbio, in the Umbria-Marche region of the northeastern Apennines of Italy. Oscillations between radiolarian cherts interbedded with foram-coccolith pelagic limestones are interpreted to follow the rhythm of precession and show hierarchical bundles, which are suggestive of eccentricity-related grouping. Eccentricity-bundles are correlated amongst the two studied sections. Moreover, the magnetic susceptibility signal of the Bottaccione section and the δ18O and δ13C record of both sections clearly demonstrate the imprint of precession and eccentricity. Eccentricity minima are associated with relatively warm periods (δ18O minima), characterized by an increased magnetic susceptibility signal and radiolarian blooms, which are expressed by frequent chert beds. Radiolarian blooms seem to hamper primary productivity, given that they correlate with δ13C minima. The delineated astronomical cycles constitute an eccentricity-based cyclostratigraphy for the Turonian part of the Scaglia Rossa. Moreover, the constructed cyclostratigraphy is anchored to numerical time by calibration with the astronomical solution La2010 (Laskar et al., 2011) and with recent radioisotopic ages from the Cenomanian-Turonian boundary interval near the GSSP in Colorado, USA (Meyers et al., 2012). The numerical age (93.9 ± 0.15 Ma; Meyers et al., 2012) of the Cenomanian-Turonian boundary (0.75 m above the top of the Bonarelli Level in the Contessa section; Tsikos et al., 2004; Kennedy et al., 2005) is used as the pinpoint to which our astronomical time-scale is anchored. Using the anchored astronomical time-scale for the Turonian of the Umbria-Marche basin, the top of the Bonarelli Level is placed at 93.97 ± 0.25 Ma, and the boundary

  12. Filling the Astronomical Void - A Visual Medium for a Visual Subject

    Science.gov (United States)

    Ryan, J.

    1996-12-01

    Astronomy is fundamentally a visual subject. The modern science of astronomy has at its foundation the ancient art of observing the sky visually. The visual elements of astronomy are arguably the most important. Every person in the entire world is affected by visually-observed astronomical phenomena such as the seasonal variations in daylight. However, misconceptions abound and the average person cannot recognize the simple signs in the sky that point to the direction, the hour and the season. Educators and astronomy popularizers widely lament that astronomy is not appreciated in our society. Yet, there is a remarkable dearth of popular literature for teaching the visual elements of astronomy. This is what I refer to as *the astronomical void.* Typical works use illustrations sparsely, relying most heavily on text-based descriptions of the visual astronomical phenomena. Such works leave significant inferential gaps to the inexperienced reader, who is unequipped for making astronomical observations. Thus, the astronomical void remains unfilled by much of the currently available literature. I therefore propose the introduction of a visually-oriented medium for teaching the visual elements of Astronomy. To this end, I have prepared a series of astronomy "comic strips" that are intended to fill the astronomical void. By giving the illustrations the central place, the comic strip medium permits the depiction of motion and other sequential activity, thus effectively representing astronomical phenomena. In addition to the practical advantages, the comic strip is a "user friendly" medium that is inviting and entertaining to a reader. At the present time, I am distributing a monthly comic strip entitled *Starman*, which appears in the newsletters of over 120 local astronomy organizations and on the web at http://www.cyberdrive.net/ starman. I hope to eventually publish a series of full-length books and believe that astronomical comic strips will help expand the perimeter of

  13. Astrophysics is easy! an introduction for the amateur astronomer

    CERN Document Server

    Inglis, Michael

    2015-01-01

    Astrophysics is often –with some justification – regarded as incomprehensible without the use of higher mathematics. Consequently, many amateur astronomers miss out on some of the most fascinating aspects of the subject. Astrophysics Is Easy! cuts through the difficult mathematics and explains the basics of astrophysics in accessible terms. Using nothing more than plain arithmetic and simple examples, the workings of the universe are outlined in a straightforward yet detailed and easy-to-grasp manner.   The original edition of the book was written over eight years ago, and in that time, advances in observational astronomy have led to new and significant changes to the theories of astrophysics. The new theories will be reflected in both the new and expanded chapters.   A unique aspect of this book is that, for each topic under discussion, an observing list is included so that observers can actually see for themselves the concepts presented –stars of the spectral sequence, nebulae, galaxies, even black ...

  14. Digging up the Earliest Astronomical Observatory in China

    Science.gov (United States)

    Li, Wei-Boa; Chen, Jiu-Jin

    2007-09-01

    At the town of Taosi, county of Xiangfen, Shanxi province the earliest (up to date about 4000 years ago) astronomical observatory and sacrificial altar relic was dug up, which consists of an observing site, some tamped soil columniations and slits between those columniations. This construction was used to observe the variations of the sunrise azimuth and determine the tropical year length in order to constitute the calendar. It is indicated from the simulated observations that the two slits located in the southeast and the northwest could be precisely used to determine the dates of the Winter Solstice and the Summer Solstice. Between those two slits there are 10 columniations which could indicate that the visual Sun moving from one columniation to another is a solar term. It implies that in the Emperor Yao time the calendar was the solar calendar in which one year was divided into 20 solar terms. The Yin-Yang five-element calendar, a 10-month calendar, in the very ancient time was based on this calendar.

  15. First light and beyond making a success of astronomical observing

    CERN Document Server

    Jenkins, D A

    2015-01-01

    Amateur astronomers who have been disappointed by the results of an observing session can still gain useful experience in a seemingly “failed” night at the telescope. In a world with imperfect seeing conditions, incredible observing sessions are often mixed with less inspiring ones, discouraging the amateur observer. This book is designed to help novice observers take something worthwhile away each and every time they go out under the night sky, regardless of what was originally planned. Almost every observer remembers his first sight of Ringed Saturn, hanging majestically in the blackness of space. Practitioners agree that visual observing is special. Real-time observations at the eyepiece can provide fleeting yet intense feelings that connect us with the universe. But when expectations aren’t met at the eyepiece, there are other ways to profit from the practice of astronomy. These rewards, though less showy, are well worth cultivating. This book will help you see what constitutes a “successful” vi...

  16. Exoplanets and Other Modern Answers to Old Astronomical Questions

    Science.gov (United States)

    Trimble, Virginia

    2002-04-01

    The Greeks were the first to ask, or at least to write about asking, questions like whether there are other planets like earth and whether the universe is finite or infinite. In all cases, they answered both yes and not (since there were lots of Greeks and not much data). A good deal later (but still in the period called history, unless you are very old), astronomers started asking whether the duration of the universe was finite or infinite, what the stars are made of and what keeps them shining, and whether there are other galaxies like ours. All of these now how answers at some confidence level. Close to 100 planets outside our solar system have been reported, starting in 1995, but selection effects mean that none are like earth. Data from many sources (supernovae, radioactive elements, microwave radiation, and all) combine to say that the universe has a finite past but probably an infinite future and an extent that, if not infinite, is anyhow very much larger than a breadbox. The stars run on nuclear fusion, and there are oodles of galaxies. The talk will explore how we have learned some of these things and try to look forward to current unsolved problems in astrophysics and cosmology.

  17. Surveying the skies how astronomers map the universe

    CERN Document Server

    Wynn-Williams, Gareth

    2016-01-01

    Since the time of Galileo, astronomy has been driven by technological innovation. With each major advance has come the opportunity and enthusiasm to survey the sky in a way that was not possible before. It is these surveys of discovery that are the subject of this book. In the first few chapters the author discusses what astronomers learned from visible-light surveys, first with the naked eye, then using telescopes in the seventeenth century, and photography in the nineteenth century. He then moves to the second half of the twentieth century when the skies started to be swept by radio, infrared, ultraviolet, x-ray and gamma ray telescopes, many of which had to be flown in satellites above the Earth’s atmosphere. These surveys led to the discovery of pulsars, quasars, molecular clouds, protostars, bursters, and black holes. He then returns to Earth to describe several currently active large-scale projects that methodically collect images, photometry and spectra that are then stored in vast publicly-accessibl...

  18. Deconvolution of astronomical images using SOR with adaptive relaxation.

    Science.gov (United States)

    Vorontsov, S V; Strakhov, V N; Jefferies, S M; Borelli, K J

    2011-07-04

    We address the potential performance of the successive overrelaxation technique (SOR) in image deconvolution, focusing our attention on the restoration of astronomical images distorted by atmospheric turbulence. SOR is the classical Gauss-Seidel iteration, supplemented with relaxation. As indicated by earlier work, the convergence properties of SOR, and its ultimate performance in the deconvolution of blurred and noisy images, can be made competitive to other iterative techniques, including conjugate gradients, by a proper choice of the relaxation parameter. The question of how to choose the relaxation parameter, however, remained open, and in the practical work one had to rely on experimentation. In this paper, using constructive (rather than exact) arguments, we suggest a simple strategy for choosing the relaxation parameter and for updating its value in consecutive iterations to optimize the performance of the SOR algorithm (and its positivity-constrained version, +SOR) at finite iteration counts. We suggest an extension of the algorithm to the notoriously difficult problem of "blind" deconvolution, where both the true object and the point-spread function have to be recovered from the blurred image. We report the results of numerical inversions with artificial and real data, where the algorithm is compared with techniques based on conjugate gradients. In all of our experiments +SOR provides the highest quality results. In addition +SOR is found to be able to detect moderately small changes in the true object between separate data frames: an important quality for multi-frame blind deconvolution where stationarity of the object is a necesessity.

  19. SUMO: operation and maintenance management web tool for astronomical observatories

    Science.gov (United States)

    Mujica-Alvarez, Emma; Pérez-Calpena, Ana; García-Vargas, María. Luisa

    2014-08-01

    SUMO is an Operation and Maintenance Management web tool, which allows managing the operation and maintenance activities and resources required for the exploitation of a complex facility. SUMO main capabilities are: information repository, assets and stock control, tasks scheduler, executed tasks archive, configuration and anomalies control and notification and users management. The information needed to operate and maintain the system must be initially stored at the tool database. SUMO shall automatically schedule the periodical tasks and facilitates the searching and programming of the non-periodical tasks. Tasks planning can be visualized in different formats and dynamically edited to be adjusted to the available resources, anomalies, dates and other constrains that can arise during daily operation. SUMO shall provide warnings to the users notifying potential conflicts related to the required personal availability or the spare stock for the scheduled tasks. To conclude, SUMO has been designed as a tool to help during the operation management of a scientific facility, and in particular an astronomical observatory. This is done by controlling all operating parameters: personal, assets, spare and supply stocks, tasks and time constrains.

  20. STEM and the Evolution of the Astronomical Star Party

    Science.gov (United States)

    Day, B. H.; Munive, P.; Franco, J.; Jones, A. P.; Shaner, A. J.; Buxner, S.; Bleacher, L.

    2015-12-01

    The astronomical star party has long been a powerful and effective way to engage the public and enhance cohesiveness within the amateur astronomy community. Early star parties tended to be strictly small, local events. But with improvements in transportation, larger regional star parties became popular. These advanced the considerable capabilities for citizen science in the amateur community, shared technology and engineering innovations in the field of telescope making, and refined numerous mathematical techniques in areas such instrument design and ephemeris generation, covering the full breadth of STEM. Advancements in astrophotography showcased at these events brought the star party from STEM to STEAM. Now, the advent of social media, web streaming, and virtual presence has facilitated the phenomenon of very large, networked star parties with international scope. These mega star parties take public engagement to a new, far greater levels, giving a vastly larger and more diverse public the opportunity to directly participate in exciting first-hand STEM activities. This presentation will recount the evolution of the star party and will focus on two examples of large, multinational, networked star parties, International Observe the Moon Night and Noche de las Estrellas. We will look at lessons learned and ways to participate.