WorldWideScience

Sample records for role-to-role connectivity profiles

  1. The Romanian International Profile and the Trade Connections with Mercosur

    Directory of Open Access Journals (Sweden)

    Ionel Sergiu Pirju

    2016-12-01

    Full Text Available The main objective of this study is to analyze the international profile of the Rumania and its trade connections with Mercosur Organization. It is also presented the Romanian infrastructure of business, the income level in Rumania, a cross cultural profile of the two regions, the national politics and the degree of openness to the European Union profile. The way to select foreign countries and markets involves a complex process in which each country is evaluated, the cross cultural study is the one who entice the importance of proximity as a key factor that can ensure the success of commercial activities between the exporting country and the country of the destination of the goods. The statistic hypotheses is: European Union membership affects the trade of Romania and its extremely high uncertainty avoidance is reflected in the reduced international competitiveness.

  2. TCP Throughput Profiles Using Measurements over Dedicated Connections

    Energy Technology Data Exchange (ETDEWEB)

    Rao, Nageswara S. [ORNL; Liu, Qiang [ORNL; Sen, Satyabrata [ORNL; Towsley, Don [University of Massachusetts, Amherst; Vardoyan, Gayane [University of Massachusetts, Amherst; Kettimuthu, R. [Argonne National Laboratory (ANL); Foster, Ian [University of Chicago

    2017-06-01

    Wide-area data transfers in high-performance computing infrastructures are increasingly being carried over dynamically provisioned dedicated network connections that provide high capacities with no competing traffic. We present extensive TCP throughput measurements and time traces over a suite of physical and emulated 10 Gbps connections with 0-366 ms round-trip times (RTTs). Contrary to the general expectation, they show significant statistical and temporal variations, in addition to the overall dependencies on the congestion control mechanism, buffer size, and the number of parallel streams. We analyze several throughput profiles that have highly desirable concave regions wherein the throughput decreases slowly with RTTs, in stark contrast to the convex profiles predicted by various TCP analytical models. We present a generic throughput model that abstracts the ramp-up and sustainment phases of TCP flows, which provides insights into qualitative trends observed in measurements across TCP variants: (i) slow-start followed by well-sustained throughput leads to concave regions; (ii) large buffers and multiple parallel streams expand the concave regions in addition to improving the throughput; and (iii) stable throughput dynamics, indicated by a smoother Poincare map and smaller Lyapunov exponents, lead to wider concave regions. These measurements and analytical results together enable us to select a TCP variant and its parameters for a given connection to achieve high throughput with statistical guarantees.

  3. Connectivity and functional profiling of abnormal brain structures in pedophilia.

    Science.gov (United States)

    Poeppl, Timm B; Eickhoff, Simon B; Fox, Peter T; Laird, Angela R; Rupprecht, Rainer; Langguth, Berthold; Bzdok, Danilo

    2015-06-01

    Despite its 0.5-1% lifetime prevalence in men and its general societal relevance, neuroimaging investigations in pedophilia are scarce. Preliminary findings indicate abnormal brain structure and function. However, no study has yet linked structural alterations in pedophiles to both connectional and functional properties of the aberrant hotspots. The relationship between morphological alterations and brain function in pedophilia as well as their contribution to its psychopathology thus remain unclear. First, we assessed bimodal connectivity of structurally altered candidate regions using meta-analytic connectivity modeling (MACM) and resting-state correlations employing openly accessible data. We compared the ensuing connectivity maps to the activation likelihood estimation (ALE) maps of a recent quantitative meta-analysis of brain activity during processing of sexual stimuli. Second, we functionally characterized the structurally altered regions employing meta-data of a large-scale neuroimaging database. Candidate regions were functionally connected to key areas for processing of sexual stimuli. Moreover, we found that the functional role of structurally altered brain regions in pedophilia relates to nonsexual emotional as well as neurocognitive and executive functions, previously reported to be impaired in pedophiles. Our results suggest that structural brain alterations affect neural networks for sexual processing by way of disrupted functional connectivity, which may entail abnormal sexual arousal patterns. The findings moreover indicate that structural alterations account for common affective and neurocognitive impairments in pedophilia. The present multimodal integration of brain structure and function analyses links sexual and nonsexual psychopathology in pedophilia. © 2015 Wiley Periodicals, Inc.

  4. Increasing user value through professional identity profiles, profile-based connection agents and games

    NARCIS (Netherlands)

    Maxwell, Katrina; Angehrn, Albert; Sereno, Bertrand

    2007-01-01

    Encouraging users of online communities to complete, maintain and improve their electronic profiles is a challenging task. Only if users see real value for themselves will they invest their time and energy in this activity, and become active contributing members of the online community. In this

  5. Measurement-based performance profiles and dynamics of UDT over dedicated connections

    Energy Technology Data Exchange (ETDEWEB)

    Foster, Ian [University of Chicago; Kettimuthu, R. [Argonne National Laboratory (ANL); Wu, Qishi [University of Memphis; Yun, Daqing [Harrisburg University; Rao, Nageswara S. [ORNL; Liu, Qiang [ORNL

    2016-11-01

    Wide-area data transfers in high-performance computing and big data scenarios are increasingly being carried over dedicated network connections that provide high capacities at low loss rates. UDP-based transport protocols are expected to be particularly well-suited for such transfers but their performance is relatively unexplored over a wide range of connection lengths, compared to TCP over shared connections. We present extensive throughput measurements of UDP-based Data Transfer (UDT) over a suite of physical and emulated 10 Gbps connections. In sharp contrast to current UDT analytical models, these measurements indicate much more complex throughput dynamics that are sensitive to the connection modality, protocol parameters, and round-trip times. Lyapunov exponents estimated from the Poincare maps of UDT traces clearly indicate regions of instability and complex dynamics. We propose a simple model based on the ramp-up and sustainment regimes of a generic transport protocol, which qualitatively illustrates the dominant monotonicity and concavity properties of throughput profiles and relates them to Lyapunov exponents. These measurements and analytical results together enable us to comprehensively evaluate UDT performance and select parameters to achieve high throughput, and they also provide guidelines for designing effective transport protocols for dedicated connections.

  6. Forecast of solar proton flux profiles for well-connected events

    Science.gov (United States)

    Ji, Eun-Young; Moon, Yong-Jae; Park, Jinhye

    2014-12-01

    We have developed a forecast model of solar proton flux profiles (> 10 MeV channel) for well-connected events. Among 136 solar proton events (SPEs) from 1986 to 2006, we select 49 well-connected ones that are all associated with single X-ray flares stronger than M1 class and start to increase within 4 h after their X-ray peak times. These events show rapid increments in proton flux. By comparing several empirical functions, we select a modified Weibull curve function to approximate a SPE flux profile. The parameters (peak flux, rise time, and decay time) of this function are determined by the relationship between X-ray flare parameters (peak flux, impulsive time, and emission measure) and SPE parameters. For 49 well-connected SPEs, the linear correlation coefficient between the predicted and the observed proton peak fluxes is 0.65 with the RMS error of 0.55 log10(pfu). In addition, we determine another forecast model based on flare and coronal mass ejection (CME) parameters using 22 SPEs. The used CME parameters are linear speed and angular width. As a result, we find that the linear correlation coefficient between the predicted and the observed proton peak fluxes is 0.83 with the RMS error of 0.35 log10(pfu). From the relationship between error of model and CME acceleration, we find that CME acceleration is an important factor for predicting proton flux profiles.

  7. Developing a forecast model of solar proton flux profiles for well-connected events

    Science.gov (United States)

    Ji, E. Y.; Moon, Y. J.; Park, J.

    2014-12-01

    We have developed a forecast model of solar proton flux profile (> 10 MeV channel) for well-connected events. Among 136 solar proton events (SPEs) from 1986 to 2006, we select 49 well-connected ones that are all associated with single X-ray flares stronger than M1 class and start to increase within four hours after their X-ray peak times. These events show rapid increments in proton flux. By comparing several empirical functions, we select a modified Weibull curve function to approximate a SPE flux profile, which is similar to the particle injection rate. The parameters (peak value, rise time and decay time) of this function are determined by the relationship between X-ray flare parameters (peak flux, impulsive time, and emission measure) and SPE parameters. For 49 well-connected SPEs, the linear correlation between the predicted proton peak flux and the observed proton peak fluxes is 0.65 with the RMS error of 0.55 pfu in the log10. In addition, we have developed another forecast model based on flare and CME parameters using 22 SPEs. The used CME parameters are linear speed and angular width. As a result, we find that the linear correlation between the predicted proton peak flux and the observed proton peak fluxes is 0.83 with the RMS error of 0.35 pfu in the log10. From the relationship between the model error and CME acceleration, we find that CME acceleration is also an important factor for predicting proton flux profiles.

  8. Reliability assessment of single-phase grid-connected PV microinverters considering mission profile and uncertainties

    DEFF Research Database (Denmark)

    Zare, Mohammad Hadi; Mohamadian, Mustafa; Wang, Huai

    2017-01-01

    Microinverters usually connect a PV panel to a Single-phase power grid. In such system, the input power is constant while the output power oscillates twice the line frequency. Thus, the input and output power differences should be stored in a storage component, which is typically an electrolytic ...... irritation of two different places on the micro inverter lifetime is studied....... capacitor. However, electrolytic capacitors are usually blamed for their short lifetime. Recently, some active power decoupling methods are introduced in the literature which can takes advantage of high reliable film capacitors. However, some extra switches and diodes are added to the microinverter which...... can influence the microinverter lifetime. This paper investigates the microinverter reliability according to mission profile where it is installed. To get more accurate results, uncertainties in both lifetime model and manufacturing process are considered. The effect of ambient temperature and solar...

  9. Functional connectivity profile of the human inferior frontal junction: involvement in a cognitive control network

    Directory of Open Access Journals (Sweden)

    Sundermann Benedikt

    2012-10-01

    Full Text Available Abstract Background The human inferior frontal junction area (IFJ is critically involved in three main component processes of cognitive control (working memory, task switching and inhibitory control. As it overlaps with several areas in established anatomical labeling schemes, it is considered to be underreported as a functionally distinct location in the neuroimaging literature. While recent studies explicitly focused on the IFJ's anatomical organization and functional role as a single brain area, it is usually not explicitly denominated in studies on cognitive networks. However based on few analyses in small datasets constrained by specific a priori assumptions on its functional specialization, the IFJ has been postulated to be part of a cognitive control network. Goal of this meta-analysis was to establish the IFJ’s connectivity profile on a high formal level of evidence by aggregating published implicit knowledge about its co-activations. We applied meta-analytical connectivity modeling (MACM based on the activation likelihood estimation (ALE method without specific assumptions regarding functional specialization on 180 (reporting left IFJ activity and 131 (right IFJ published functional neuroimaging experiments derived from the BrainMap database. This method is based on coordinates in stereotaxic space, not on anatomical descriptors. Results The IFJ is significantly co-activated with areas in the dorsolateral and ventrolateral prefrontal cortex, anterior insula, medial frontal gyrus / pre-SMA, posterior parietal cortex, occipitotemporal junction / cerebellum, thalamus and putamen as well as language and motor areas. Results are corroborated by an independent resting-state fMRI analysis. Conclusions These results support the assumption that the IFJ is part of a previously described cognitive control network. They also highlight the involvement of subcortical structures in this system. A direct line is drawn from works on the functional

  10. Connective processing by bilingual children and monolinguals with specific language impairment : distinct profiles

    NARCIS (Netherlands)

    Mak, W.M.; Tribushinina, E.; Lomako, Julia; Gagarina, N.; Abrosova, Ekaterina; Sanders, T.J.M.

    2017-01-01

    Production studies show that both Russian-speaking children with specific language impairment (SLI) and bilingual children for whom Russian is a non-dominant language have difficulty distinguishing between the near-synonymous connectives i ‘and’ and a ‘and/but’. I is a preferred connective when

  11. Classification of early-stage non-small cell lung cancer by weighing gene expression profiles with connectivity information.

    Science.gov (United States)

    Zhang, Ao; Tian, Suyan

    2018-05-01

    Pathway-based feature selection algorithms, which utilize biological information contained in pathways to guide which features/genes should be selected, have evolved quickly and become widespread in the field of bioinformatics. Based on how the pathway information is incorporated, we classify pathway-based feature selection algorithms into three major categories-penalty, stepwise forward, and weighting. Compared to the first two categories, the weighting methods have been underutilized even though they are usually the simplest ones. In this article, we constructed three different genes' connectivity information-based weights for each gene and then conducted feature selection upon the resulting weighted gene expression profiles. Using both simulations and a real-world application, we have demonstrated that when the data-driven connectivity information constructed from the data of specific disease under study is considered, the resulting weighted gene expression profiles slightly outperform the original expression profiles. In summary, a big challenge faced by the weighting method is how to estimate pathway knowledge-based weights more accurately and precisely. Only until the issue is conquered successfully will wide utilization of the weighting methods be impossible. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Mission Profile Translation to Capacitor Stresses in Grid-Connected Photovoltaic Systems

    DEFF Research Database (Denmark)

    Yang, Yongheng; Ma, Ke; Wang, Huai

    2014-01-01

    DC capacitors are widely adopted in grid-connected PhotoVoltaic(PV) systems for power stabilization and control decoupling. They have become one of the critical components in grid-connected PV inverters in terms of cost, reliability and volume. The electrical and thermal stresses of the DC...... stresses of the DC capacitors under both normal and abnormal grid conditions. As a consequence, this investigation provides new insights into the sizing and reliability prediction of those capacitors with respect to priorart studies. Two study cases on a single-stage PV inverter and a two-stage PV inverter...

  13. Functional Connectivity and Genetic Profile of a “Double-Cortex”-Like Malformation

    Science.gov (United States)

    Sprugnoli, Giulia; Vatti, Giampaolo; Rossi, Simone; Cerase, Alfonso; Renieri, Alessandra; Mencarelli, Maria A.; Zara, Federico; Rossi, Alessandro; Santarnecchi, Emiliano

    2018-01-01

    Laminar heterotopia is a rare condition consisting in an extra layer of gray matter under properly migrated cortex; it configures an atypical presentation of periventricular nodular heterotopia (PNH) or a double cortex (DC) syndrome. We conducted an original functional MRI (fMRI) analysis in a drug-resistant epilepsy patient with “double-cortex”-like malformation to reveal her functional connectivity (FC) as well as a wide genetic analysis to identify possible genetic substrates. Heterotopias were segmented into region of interests (ROIs), whose voxel-wise FC was compared to that of (i) its normally migrated counterpart, (ii) its contralateral homologous, and (iii) those of 30 age-matched healthy controls. Extensive genetic analysis was conducted to screen cortical malformations-associated genes. Compared to healthy controls, both laminar heterotopias and the overlying cortex showed significant reduction of FC with the contralateral hemisphere. Two heterozygous variants of uncertain clinical significance were found, involving autosomal recessive disease-causing genes, FAT4 and COL18A1. This first FC analysis of a unique case of “double-cortex”-like malformation revealed a hemispheric connectivity segregation both in the laminar cortex as in the correctly migrated one, with a new pattern of genes’ mutations. Our study suggests the altered FC could have an electrophysiological and functional impact on large-scale brain networks, and the involvement of not yet identified genes in “double-cortex”-like malformation with a possible role of rare variants in recessive genes as pathogenic cofactors. PMID:29946244

  14. Transcript profiling of Wilms tumors reveals connections to kidney morphogenesis and expression patterns associated with anaplasia.

    Science.gov (United States)

    Li, Wenliang; Kessler, Patricia; Williams, Bryan R G

    2005-01-13

    Anaplasia (unfavorable histology) is associated with therapy resistance and poor prognosis of Wilms tumor, but the molecular basis for this phenotype is unclear. Here, we used a cDNA array with 9240 clones relevant to cancer biology and/or kidney development to examine the expression profiles of 54 Wilms tumors, five normal kidneys and fetal kidney. By linking genes differentially expressed between fetal kidney and Wilms tumors to kidney morphogenesis, we found that genes expressed at a higher level in Wilms tumors tend to be expressed more in uninduced metanephrogenic mesenchyme or blastema than in their differentiated structures. Conversely, genes expressed at a lower level in Wilms tumors tend to be expressed less in uninduced metanephrogenic mesenchyme or blastema. We also identified 97 clones representing 76 Unigenes or unclustered ESTs that clearly separate anaplastic Wilms tumors from tumors with favorable histology. Genes in this set provide insight into the nature of the abnormal nuclear morphology of anaplastic tumors and may facilitate identification of molecular targets to improve their responsiveness to treatment.

  15. Dynamic Metabolite Profiling in an Archaeon Connects Transcriptional Regulation to Metabolic Consequences.

    Directory of Open Access Journals (Sweden)

    Horia Todor

    Full Text Available Previous work demonstrated that the TrmB transcription factor is responsible for regulating the expression of many enzyme-coding genes in the hypersaline-adapted archaeon Halobacterium salinarum via a direct interaction with a cis-regulatory sequence in their promoters. This interaction is abolished in the presence of glucose. Although much is known about the effects of TrmB at the transcriptional level, it remains unclear whether and to what extent changes in mRNA levels directly affect metabolite levels. In order to address this question, here we performed a high-resolution metabolite profiling time course during a change in nutrients using a combination of targeted and untargeted methods in wild-type and ΔtrmB strain backgrounds. We found that TrmB-mediated transcriptional changes resulted in widespread and significant changes to metabolite levels across the metabolic network. Additionally, the pattern of growth complementation using various purines suggests that the mis-regulation of gluconeogenesis in the ΔtrmB mutant strain in the absence of glucose results in low phosphoribosylpyrophosphate (PRPP levels. We confirmed these low PRPP levels using a quantitative mass spectrometric technique and found that they are associated with a metabolic block in de novo purine synthesis, which is partially responsible for the growth defect of the ΔtrmB mutant strain in the absence of glucose. In conclusion, we show how transcriptional regulation of metabolism affects metabolite levels and ultimately, phenotypes.

  16. Dynamic Metabolite Profiling in an Archaeon Connects Transcriptional Regulation to Metabolic Consequences.

    Science.gov (United States)

    Todor, Horia; Gooding, Jessica; Ilkayeva, Olga R; Schmid, Amy K

    2015-01-01

    Previous work demonstrated that the TrmB transcription factor is responsible for regulating the expression of many enzyme-coding genes in the hypersaline-adapted archaeon Halobacterium salinarum via a direct interaction with a cis-regulatory sequence in their promoters. This interaction is abolished in the presence of glucose. Although much is known about the effects of TrmB at the transcriptional level, it remains unclear whether and to what extent changes in mRNA levels directly affect metabolite levels. In order to address this question, here we performed a high-resolution metabolite profiling time course during a change in nutrients using a combination of targeted and untargeted methods in wild-type and ΔtrmB strain backgrounds. We found that TrmB-mediated transcriptional changes resulted in widespread and significant changes to metabolite levels across the metabolic network. Additionally, the pattern of growth complementation using various purines suggests that the mis-regulation of gluconeogenesis in the ΔtrmB mutant strain in the absence of glucose results in low phosphoribosylpyrophosphate (PRPP) levels. We confirmed these low PRPP levels using a quantitative mass spectrometric technique and found that they are associated with a metabolic block in de novo purine synthesis, which is partially responsible for the growth defect of the ΔtrmB mutant strain in the absence of glucose. In conclusion, we show how transcriptional regulation of metabolism affects metabolite levels and ultimately, phenotypes.

  17. Profiles

    International Nuclear Information System (INIS)

    2004-01-01

    Profiles is a synthetic overview of more than 100 national energy markets in the world, providing insightful facts and key energy statistics. A Profile is structured around 6 main items and completed by key statistics: Ministries, public agencies, energy policy are concerned; main companies in the oil, gas, electricity and coal sectors, status, shareholders; reserve, production, imports and exports, electricity and refining capacities; deregulation of prices, subsidies, taxes; consumption trends by sector, energy market shares; main energy projects, production and consumption prospects. Statistical Profiles are present in about 3 pages the main data and indicators on oil, gas, coal and electricity. (A.L.B.)

  18. Characterization of the fiber connectivity profile of the cerebral cortex in schizotypal personality disorder: A pilot study

    Directory of Open Access Journals (Sweden)

    Kai eLiu

    2016-05-01

    Full Text Available Schizotypal personality disorder (SPD is considered one of the classic disconnection syndromes. However, the specific cortical disconnectivity pattern has not been fully investigated. In this study, we aimed to explore significant alterations in whole-cortex structural connectivity in SPD individuals (SPDs by combining the techniques of brain surface morphometry and white matter (WM tractography. Diffusion and structural MR data were collected from twenty subjects with SPD (all males; age, 19.7 ± 0.9 yrs and eighteen healthy controls (all males; age, 20.3 ± 1.0 yrs. To measure the structural connectivity for a given unit area of the cortex, the fiber connectivity density (FiCD value was proposed and calculated as the sum of the fractional anisotropy of all the fibers connecting to that unit area in tractography. Then, the resultant whole-cortex FiCD maps were compared in a vertex-wise manner between SPDs and controls. Compared with normal controls, SPDs showed significantly decreased FiCD in the rostral middle frontal gyrus (crossing BA9 and BA10 and significantly increased FiCD in the anterior part of the fusiform/inferior temporal cortex (P < 0.05, Monte Carlo simulation corrected. Moreover, the gray matter volume extracted from the left rostral middle frontal cluster was observed to be significantly greater in the SPD group (P = 0.02. Overall, this study identifies a decrease in connectivity in the left middle frontal cortex as a key neural deficit at the whole-cortex level in SPD, thus providing insight into its neuropathological basis.

  19. A Path to Alignment: Connecting K-12 and Higher Education via the Common Core and the Degree Qualifications Profile

    Science.gov (United States)

    Conley, David T.; Gaston, Paul L.

    2013-01-01

    The Common Core State Standards (CCSS), which aim to assure competency in English/language arts and mathematics through the K-12 curriculum, define necessary but not sufficient preparedness for success in college. The Degree Qualifications Profile (DQP), which describes what a college degree should signify, regardless of major, offers useful but…

  20. Profile of mathematical reasoning ability of 8th grade students seen from communicational ability, basic skills, connection, and logical thinking

    Science.gov (United States)

    Sumarsih; Budiyono; Indriati, D.

    2018-04-01

    This research aims to understand the students’ weaknesses in mathematical reasoning ability in junior secondary school. A set of multiple choice tests were used to measure this ability involve components mathematical communication, basic skills, connection, and logical thinking. A total of 259 respondents were determined by stratified cluster random sampling. Data were analyzed using one-way Anova test with Fobs = 109.5760 and F = 3.0000. The results show that students’ ability from schools with high National Exam in mathematics category was the best and followed by medium and low category. Mathematical connection is the most difficult component performed by students. In addition, most students also have difficulty in expressing ideas and developing logical arguments.

  1. A two-dimensional statistical framework connecting thermodynamic profiles with filaments in the scrape off layer and application to experiments

    Science.gov (United States)

    Militello, F.; Farley, T.; Mukhi, K.; Walkden, N.; Omotani, J. T.

    2018-05-01

    A statistical framework was introduced in Militello and Omotani [Nucl. Fusion 56, 104004 (2016)] to correlate the dynamics and statistics of L-mode and inter-ELM plasma filaments with the radial profiles of thermodynamic quantities they generate in the Scrape Off Layer. This paper extends the framework to cases in which the filaments are emitted from the separatrix at different toroidal positions and with a finite toroidal velocity. It is found that the toroidal velocity does not affect the profiles, while the toroidal distribution of filament emission renormalises the waiting time between two events. Experimental data collected by visual camera imaging are used to evaluate the statistics of the fluctuations, to inform the choice of the probability distribution functions used in the application of the framework. It is found that the toroidal separation of the filaments is exponentially distributed, thus suggesting the lack of a toroidal modal structure. Finally, using these measurements, the framework is applied to an experimental case and good agreement is found.

  2. Assessment of T Regulatory Cells and Expanded Profiling of Autoantibodies May Offer Novel Biomarkers for the Clinical Management of Systemic Sclerosis and Undifferentiated Connective Tissue Disease

    Directory of Open Access Journals (Sweden)

    Paola Cordiali-Fei

    2013-01-01

    Full Text Available In order to identify disease biomarkers for the clinical and therapeutic management of autoimmune diseases such as systemic sclerosis (SSc and undifferentiated connective tissue disease (UCTD, we have explored the setting of peripheral T regulatory (T reg cells and assessed an expanded profile of autoantibodies in patients with SSc, including either limited (lcSSc or diffuse (dcSSc disease, and in patients presenting with clinical signs and symptoms of UCTD. A large panel of serum antibodies directed towards nuclear, nucleolar, and cytoplasmic antigens, including well-recognized molecules as well as less frequently tested antigens, was assessed in order to determine whether different antibody profiles might be associated with distinct clinical settings. Beside the well-recognized association between lcSSc and anti-centromeric or dcSSC and anti-topoisomerase-I antibodies, we found a significative association between dcSSc and anti-SRP or anti-PL-7/12 antibodies. In addition, two distinct groups emerged on the basis of anti-RNP or anti-PM-Scl 75/100 antibody production among UCTD patients. The levels of T reg cells were significantly lower in patients with SSc as compared to patients with UCTD or to healthy controls; in patients with lcSSc, T reg cells were inversely correlated to disease duration, suggesting that their levels may represent a marker of disease progression.

  3. Axial velocity profiles and secondary flows of developing laminar flows in a straight connected exit region of a 180 .deg. square curved duct

    Energy Technology Data Exchange (ETDEWEB)

    Sohn, Hyun Chull; Lee, Heang Nam; Park, Gil Moon [Chosun Univ., Gwangju (Korea, Republic of)

    2005-10-01

    In the present study, characteristics of steady state laminar flows of a straight duct connected to a 180 .deg. curved duct were examined in the entrance region through experimental and numerical analyses. For the analysis, the governing equations of laminar flows in the Cartesian coordinate system were applied. Flow characteristics such as velocity profiles and secondary flows were investigated numerically and experimentally in a square cross-sectional straight duct by the PIV system and a CFD code (STARCD). For the PIV measurement, smoke particles produced from mosquito coils. The experimental data were obtained at 9 points dividing the test sections by 400 mm. Experimental and numerical results can be summarized as follows. 1) Reynolds number, Re was increased, dimensionless velocity profiles at the outer wall were increased due to the effect of the centrifugal force and secondary flows. 2) The intensity of a secondary flow became stronger at the inner wall rather than the outer wall regardless of Reynolds number. Especially, fluid dynamic phenomenon called conner impact were observed at dimensionless axial position, x/D{sub h}=50.

  4. Connecting Grammaticalisation

    DEFF Research Database (Denmark)

    Nørgård-Sørensen, Jens; Heltoft, Lars; Schøsler, Lene

    morphological, topological and constructional paradigms often connect to form complex paradigms. The book introduces the concept of connecting grammaticalisation to describe the formation, restructuring and dismantling of such complex paradigms. Drawing primarily on data from Germanic, Romance and Slavic...

  5. Making Connections

    Science.gov (United States)

    Pien, Cheng Lu; Dongsheng, Zhao

    2011-01-01

    Effective teaching includes enabling learners to make connections within mathematics. It is easy to accord with this statement, but how often is it a reality in the mathematics classroom? This article describes an approach in "connecting equivalent" fractions and whole number operations. The authors illustrate how a teacher can combine a common…

  6. About Connections

    Directory of Open Access Journals (Sweden)

    Kathleen S Rockland

    2015-05-01

    Full Text Available Despite the attention attracted by connectomics, one can lose sight of the very real questions concerning What are connections? In the neuroimaging community, structural connectivity is ground truth and underlying constraint on functional or effective connectivity. It is referenced to underlying anatomy; but, as increasingly remarked, there is a large gap between the wealth of human brain mapping and the relatively scant data on actual anatomical connectivity. Moreover, connections have typically been discussed as pairwise, point x projecting to point y (or: to points y and z, or more recently, in graph theoretical terms, as nodes or regions and the interconnecting edges. This is a convenient shorthand, but tends not to capture the richness and nuance of basic anatomical properties as identified in the classic tradition of tracer studies. The present short review accordingly revisits connectional weights, heterogeneity, reciprocity, topography, and hierarchical organization, drawing on concrete examples. The emphasis is on presynaptic long-distance connections, motivated by the intention to probe current assumptions and promote discussions about further progress and synthesis.

  7. GC-MS metabolic profiling of Cabernet Sauvignon and Merlot cultivars during grapevine berry development and network analysis reveals a stage- and cultivar-dependent connectivity of primary metabolites.

    Science.gov (United States)

    Cuadros-Inostroza, Alvaro; Ruíz-Lara, Simón; González, Enrique; Eckardt, Aenne; Willmitzer, Lothar; Peña-Cortés, Hugo

    Information about the total chemical composition of primary metabolites during grape berry development is scarce, as are comparative studies trying to understand to what extent metabolite modifications differ between cultivars during ripening. Thus, correlating the metabolic profiles with the changes occurring in berry development and ripening processes is essential to progress in their comprehension as well in the development of new approaches to improve fruit attributes. Here, the developmental metabolic profiling analysis across six stages from flowering to fully mature berries of two cultivars, Cabernet Sauvignon and Merlot, is reported at metabolite level. Based on a gas chromatography-mass spectrometry untargeted approach, 115 metabolites were identified and relative quantified in both cultivars. Sugars and amino acids levels show an opposite behaviour in both cultivars undergoing a highly coordinated shift of metabolite associated to primary metabolism during the stages involved in growth, development and ripening of berries. The changes are characteristic for each stage, the most pronounced ones occuring at fruit setting and pre-Veraison. They are associated to a reduction of the levels of metabolites present in the earlier corresponding stage, revealing a required catabolic activity of primary metabolites for grape berry developmental process. Network analysis revealed that the network connectivity of primary metabolites is stage- and cultivar-dependent, suggesting differences in metabolism regulation between both cultivars as the maturity process progresses. Furthermore, network analysis may represent an appropriate method to display the association between primary metabolites during berry developmental processes among different grapevine cultivars and for identifying potential biologically relevant metabolites.

  8. Internet Connectivity

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Internet Connectivity. BSNL, SIFY, HCL in Guwahati; only BSNL elsewhere in NE (local player in Shillong). Service poor; All vendors lease BW from BSNL.

  9. Mathematics Connection

    African Journals Online (AJOL)

    MATHEMATICS CONNECTION aims at providing a forum topromote the development of Mathematics Education in Ghana. Articles that seekto enhance the teaching and/or learning of mathematics at all levels of theeducational system are welcome.

  10. HR Connect

    Data.gov (United States)

    US Agency for International Development — HR Connect is the USAID HR personnel system which allows HR professionals to process HR actions related to employee's personal and position information. This system...

  11. Establishing Connectivity

    DEFF Research Database (Denmark)

    Kjær, Poul F.

    Global law settings are characterised by a structural pre-eminence of connectivity norms, a type of norm which differs from coherency or possibility norms. The centrality of connectivity norms emerges from the function of global law, which is to increase the probability of transfers of condensed ...... and human rights can be understood as serving a constitutionalising function aimed at stabilising and facilitating connectivity. This allows for an understanding of colonialism and contemporary global governance as functional, but not as normative, equivalents.......Global law settings are characterised by a structural pre-eminence of connectivity norms, a type of norm which differs from coherency or possibility norms. The centrality of connectivity norms emerges from the function of global law, which is to increase the probability of transfers of condensed...... social components, such as economic capital and products, religious doctrines and scientific knowledge, from one legally structured context to another within world society. This was the case from colonialism and colonial law to contemporary global supply chains and human rights. Both colonial law...

  12. Connected Traveler

    Energy Technology Data Exchange (ETDEWEB)

    2016-06-01

    The Connected Traveler framework seeks to boost the energy efficiency of personal travel and the overall transportation system by maximizing the accuracy of predicted traveler behavior in response to real-time feedback and incentives. It is anticipated that this approach will establish a feedback loop that 'learns' traveler preferences and customizes incentives to meet or exceed energy efficiency targets by empowering individual travelers with information needed to make energy-efficient choices and reducing the complexity required to validate transportation system energy savings. This handout provides an overview of NREL's Connected Traveler project, including graphics, milestones, and contact information.

  13. Making connections

    NARCIS (Netherlands)

    Marion Duimel

    2007-01-01

    Original title: Verbinding maken; senioren en internet. More and more older people are finding their way to the Internet. Many people aged over 50 who have only recently gone online say that a new world has opened up for them. By connecting to the Internet they have the feeling that they

  14. CMS Connect

    Science.gov (United States)

    Balcas, J.; Bockelman, B.; Gardner, R., Jr.; Hurtado Anampa, K.; Jayatilaka, B.; Aftab Khan, F.; Lannon, K.; Larson, K.; Letts, J.; Marra Da Silva, J.; Mascheroni, M.; Mason, D.; Perez-Calero Yzquierdo, A.; Tiradani, A.

    2017-10-01

    The CMS experiment collects and analyzes large amounts of data coming from high energy particle collisions produced by the Large Hadron Collider (LHC) at CERN. This involves a huge amount of real and simulated data processing that needs to be handled in batch-oriented platforms. The CMS Global Pool of computing resources provide +100K dedicated CPU cores and another 50K to 100K CPU cores from opportunistic resources for these kind of tasks and even though production and event processing analysis workflows are already managed by existing tools, there is still a lack of support to submit final stage condor-like analysis jobs familiar to Tier-3 or local Computing Facilities users into these distributed resources in an integrated (with other CMS services) and friendly way. CMS Connect is a set of computing tools and services designed to augment existing services in the CMS Physics community focusing on these kind of condor analysis jobs. It is based on the CI-Connect platform developed by the Open Science Grid and uses the CMS GlideInWMS infrastructure to transparently plug CMS global grid resources into a virtual pool accessed via a single submission machine. This paper describes the specific developments and deployment of CMS Connect beyond the CI-Connect platform in order to integrate the service with CMS specific needs, including specific Site submission, accounting of jobs and automated reporting to standard CMS monitoring resources in an effortless way to their users.

  15. Gendered Connections

    DEFF Research Database (Denmark)

    Jensen, Steffen Bo

    2009-01-01

    This article explores the gendered nature of urban politics in Cape Town by focusing on a group of female, township politicians. Employing the Deleuzian concept of `wild connectivity', it argues that these politically entrepreneurial women were able to negotiate a highly volatile urban landscape...... by drawing on and operationalizing violent, male networks — from struggle activists' networks, to vigilante groups and gangs, to the police. The fact that they were women helped them to tap into and exploit these networks. At the same time, they were restricted by their sex, as their ability to navigate...... space also drew on quite traditional notions of female respectability. Furthermore, the article argues, the form of wild connectivity to an extent was a function of the political transition, which destabilized formal structures of gendered authority. It remains a question whether this form...

  16. Cosmic Connections

    CERN Document Server

    Ellis, Jonathan Richard

    2003-01-01

    A National Research Council study on connecting quarks with the cosmos has recently posed a number of the more important open questions at the interface between particle physics and cosmology. These questions include the nature of dark matter and dark energy, how the Universe began, modifications to gravity, the effects of neutrinos on the Universe, how cosmic accelerators work, and whether there are new states of matter at high density and pressure. These questions are discussed in the context of the talks presented at this Summer Institute.

  17. Places Connected:

    DEFF Research Database (Denmark)

    Hansen, Annette Skovsted

    This paper argues that development assistance contributed to the globalization of the 20th century by financing truly global networks of people. By focusing on the networks financed by development assistance bound by the national histories of Denmark and Japan, I illustrate how the people who...... experiences of place, however, when it is often the same people who experience many different places? Along with many other so-called donors in the 1950s, Denmark and Japan chose to invest in the education of own and other nationals involved in development and thereby financed personal connections between...... individuals throughout the world. Development assistance , where there are two or three links only between a Bangladeshi farmer, a street child in Sao Paolo and the President of the United States, the Queen of Denmark, or a suburban house wife in Japan, who has never left the Osaka area, but mothered a United...

  18. Investigation into Methods for Predicting Connection Temperatures

    Directory of Open Access Journals (Sweden)

    K. Anderson

    2009-01-01

    Full Text Available The mechanical response of connections in fire is largely based on material strength degradation and the interactions between the various components of the connection. In order to predict connection performance in fire, temperature profiles must initially be established in order to evaluate the material strength degradation over time. This paper examines two current methods for predicting connection temperatures: The percentage method, where connection temperatures are calculated as a percentage of the adjacent beam lower-flange, mid-span temperatures; and the lumped capacitance method, based on the lumped mass of the connection. Results from the percentage method do not correlate well with experimental results, whereas the lumped capacitance method shows much better agreement with average connection temperatures. A 3D finite element heat transfer model was also created in Abaqus, and showed good correlation with experimental results. 

  19. Design of Steel Beam-Column Connections

    Directory of Open Access Journals (Sweden)

    Bogatinoski Z.

    2014-05-01

    Full Text Available In this paper a theoretical and experimental research of the steel beam-column connections is presented. Eight types of specimens were being researched, composed of rigid and semi-rigid connections from which 4 connections are with IPE - profile and 4 connections with tube's section for the beam. From the numerical analysis of the researched models, and especially from the experimental research at the Laboratory for Structures in the Faculty of Mechanical Engineering - Skopje, specific conclusions were received that ought to have theoretical and practical usage for researchers in this area of interest.

  20. Minimum cost connection networks

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Tvede, Mich

    In the present paper we consider the allocation of cost in connection networks. Agents have connection demands in form of pairs of locations they want to be connected. Connections between locations are costly to build. The problem is to allocate costs of networks satisfying all connection demands...

  1. Personal summarization from profile networks

    Institute of Scientific and Technical Information of China (English)

    Zhongqing WANG; Shoushan LI; Guodong ZHOU

    2017-01-01

    Personal profile information on social media like Linkedln.com and Facebook.com is at the core of many interesting applications,such as talent recommendation and contextual advertising.However,personal profiles usually lack consistent organization confronted with the large amount of available information.Therefore,it is always a challenge for people to quickly find desired information from them.In this paper,we address the task of personal profile summarization by leveraging both textual information and social connection information in social networks from both unsupervised and supervised learning paradigms.Here,using social connection information is motivated by the intuition that people with similar academic,business or social background (e.g.,comajor,co-university,and co-corporation) tend to have similar experiences and should have similar summaries.For unsupervised learning,we propose a collective ranking approach,called SocialRank,to combine textual information in an individual profile and social context information from relevant profiles in generating a personal profile summary.For supervised learning,we propose a collective factor graph model,called CoFG,to summarize personal profiles with local textual attribute functions and social connection factors.Extensive evaluation on a large dataset from LinkedIn.com demonstrates the usefulness of social connection information in personal profile summarization and the effectiveness of our proposed unsupervised and supervised learning approaches.

  2. DISSECTING HABITAT CONNECTIVITY

    Science.gov (United States)

    abstractConnectivity is increasingly recognized as an important element of a successful reserve design. Connectivity matters in reserve design to the extent that it promotes or hinders the viability of target populations. While conceptually straightforward, connectivity i...

  3. Mixed Connective Tissue Disease

    Science.gov (United States)

    Mixed connective tissue disease Overview Mixed connective tissue disease has signs and symptoms of a combination of disorders — primarily lupus, scleroderma and polymyositis. For this reason, mixed connective tissue disease ...

  4. Undifferentiated Connective Tissue Disease

    Science.gov (United States)

    ... Home Conditions Undifferentiated Connective Tissue Disease (UCTD) Undifferentiated Connective Tissue Disease (UCTD) Make an Appointment Find a Doctor ... by Barbara Goldstein, MD (February 01, 2016) Undifferentiated connective tissue disease (UCTD) is a systemic autoimmune disease. This ...

  5. Intermodal Passenger Connectivity Database -

    Data.gov (United States)

    Department of Transportation — The Intermodal Passenger Connectivity Database (IPCD) is a nationwide data table of passenger transportation terminals, with data on the availability of connections...

  6. Minimum cost connection networks

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Tvede, Mich

    2015-01-01

    In the present paper we consider the allocation of costs in connection networks. Agents have connection demands in form of pairs of locations they want to have connected. Connections between locations are costly to build. The problem is to allocate costs of networks satisfying all connection...... demands. We use a few axioms to characterize allocation rules that truthfully implement cost minimizing networks satisfying all connection demands in a game where: (1) a central planner announces an allocation rule and a cost estimation rule; (2) every agent reports her own connection demand as well...... as all connection costs; (3) the central planner selects a cost minimizing network satisfying reported connection demands based on the estimated costs; and, (4) the planner allocates the true costs of the selected network. It turns out that an allocation rule satisfies the axioms if and only if relative...

  7. Connected vehicle standards.

    Science.gov (United States)

    2016-01-01

    Connected vehicles have the potential to transform the way Americans travel by : allowing cars, buses, trucks, trains, traffic signals, smart phones, and other devices to : communicate through a safe, interoperable wireless network. A connected vehic...

  8. Data Profiling

    OpenAIRE

    Hladíková, Radka

    2010-01-01

    Title: Data Profiling Author: Radka Hladíková Department: Department of Software Engineering Supervisor: Ing. Vladimír Kyjonka Supervisor's e-mail address: Abstract: This thesis puts mind on problems with data quality and data profiling. This Work analyses and summarizes problems of data quality, data defects, process of data quality, data quality assessment and data profiling. The main topic is data profiling as a process of researching data available in existing...

  9. Connecting to Everyday Practices

    DEFF Research Database (Denmark)

    Iversen, Ole Sejer; Smith, Rachel Charlotte

    2012-01-01

    construction and reproduction of cultural heritage creating novel connections between self and others and between past, present and future. We present experiences from a current research project, the Digital Natives exhibition, in which social media was designed as an integral part of the exhibition to connect...... focusing on the connections between audiences practices and the museum exhibition....

  10. Network connectivity value.

    Science.gov (United States)

    Dragicevic, Arnaud; Boulanger, Vincent; Bruciamacchie, Max; Chauchard, Sandrine; Dupouey, Jean-Luc; Stenger, Anne

    2017-04-21

    In order to unveil the value of network connectivity, we formalize the construction of ecological networks in forest environments as an optimal control dynamic graph-theoretic problem. The network is based on a set of bioreserves and patches linked by ecological corridors. The node dynamics, built upon the consensus protocol, form a time evolutive Mahalanobis distance weighted by the opportunity costs of timber production. We consider a case of complete graph, where the ecological network is fully connected, and a case of incomplete graph, where the ecological network is partially connected. The results show that the network equilibrium depends on the size of the reception zone, while the network connectivity depends on the environmental compatibility between the ecological areas. Through shadow prices, we find that securing connectivity in partially connected networks is more expensive than in fully connected networks, but should be undertaken when the opportunity costs are significant. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Karolinske psychodynamic profile (KAPP)

    DEFF Research Database (Denmark)

    Mathiesen, Birgit Bork; Søgaard, Ulf

    2006-01-01

    psykologiske testmetoder, assesment, Karolinska psychodynamic profile (KAPP), psykodynamisk profil......psykologiske testmetoder, assesment, Karolinska psychodynamic profile (KAPP), psykodynamisk profil...

  12. Functional connectome fingerprinting: identifying individuals using patterns of brain connectivity.

    Science.gov (United States)

    Finn, Emily S; Shen, Xilin; Scheinost, Dustin; Rosenberg, Monica D; Huang, Jessica; Chun, Marvin M; Papademetris, Xenophon; Constable, R Todd

    2015-11-01

    Functional magnetic resonance imaging (fMRI) studies typically collapse data from many subjects, but brain functional organization varies between individuals. Here we establish that this individual variability is both robust and reliable, using data from the Human Connectome Project to demonstrate that functional connectivity profiles act as a 'fingerprint' that can accurately identify subjects from a large group. Identification was successful across scan sessions and even between task and rest conditions, indicating that an individual's connectivity profile is intrinsic, and can be used to distinguish that individual regardless of how the brain is engaged during imaging. Characteristic connectivity patterns were distributed throughout the brain, but the frontoparietal network emerged as most distinctive. Furthermore, we show that connectivity profiles predict levels of fluid intelligence: the same networks that were most discriminating of individuals were also most predictive of cognitive behavior. Results indicate the potential to draw inferences about single subjects on the basis of functional connectivity fMRI.

  13. Attractor neural networks with resource-efficient synaptic connectivity

    Science.gov (United States)

    Pehlevan, Cengiz; Sengupta, Anirvan

    Memories are thought to be stored in the attractor states of recurrent neural networks. Here we explore how resource constraints interplay with memory storage function to shape synaptic connectivity of attractor networks. We propose that given a set of memories, in the form of population activity patterns, the neural circuit choses a synaptic connectivity configuration that minimizes a resource usage cost. We argue that the total synaptic weight (l1-norm) in the network measures the resource cost because synaptic weight is correlated with synaptic volume, which is a limited resource, and is proportional to neurotransmitter release and post-synaptic current, both of which cost energy. Using numerical simulations and replica theory, we characterize optimal connectivity profiles in resource-efficient attractor networks. Our theory explains several experimental observations on cortical connectivity profiles, 1) connectivity is sparse, because synapses are costly, 2) bidirectional connections are overrepresented and 3) are stronger, because attractor states need strong recurrence.

  14. Handbook of networking & connectivity

    CERN Document Server

    McClain, Gary R

    1994-01-01

    Handbook of Networking & Connectivity focuses on connectivity standards in use, including hardware and software options. The book serves as a guide for solving specific problems that arise in designing and maintaining organizational networks.The selection first tackles open systems interconnection, guide to digital communications, and implementing TCP/IP in an SNA environment. Discussions focus on elimination of the SNA backbone, routing SNA over internets, connectionless versus connection-oriented networks, internet concepts, application program interfaces, basic principles of layering, proto

  15. 78 FR 55684 - ConnectED Workshop

    Science.gov (United States)

    2013-09-11

    ... tools move everything from homework assignments to testing into the cloud. The workshop will explore possible strategies to connect virtually all of our students to next-generation broadband in a timely, cost-effective way. It will also share promising practices, from NTIA's Broadband Technology Opportunities...

  16. The Connected Traveler

    Energy Technology Data Exchange (ETDEWEB)

    Young, Stanley

    2017-04-24

    The Connected Traveler project is a multi-disciplinary undertaking that seeks to validate potential for transformative transportation system energy savings by incentivizing energy efficient travel behavior.

  17. Connections: All Issues

    Science.gov (United States)

    Goals Recycling Green Purchasing Pollution Prevention Reusing Water Resources Environmental Management Plateau, and more... Connections Newsletter December 2016 December 2016 Science-themed gifts available at

  18. Archives: Mathematics Connection

    African Journals Online (AJOL)

    Items 1 - 9 of 9 ... Archives: Mathematics Connection. Journal Home > Archives: Mathematics Connection. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 9 of 9 Items. 2011 ...

  19. Connective Tissue Disorders

    Science.gov (United States)

    ... of connective tissue. Over 200 disorders that impact connective tissue. There are different types: Genetic disorders, such as Ehlers-Danlos syndrome, Marfan syndrome, and osteogenesis imperfecta Autoimmune disorders, such as lupus and scleroderma Cancers, like some types of soft tissue sarcoma Each ...

  20. Generalized connectivity of graphs

    CERN Document Server

    Li, Xueliang

    2016-01-01

    Noteworthy results, proof techniques, open problems and conjectures in generalized (edge-) connectivity are discussed in this book. Both theoretical and practical analyses for generalized (edge-) connectivity of graphs are provided. Topics covered in this book include: generalized (edge-) connectivity of graph classes, algorithms, computational complexity, sharp bounds, Nordhaus-Gaddum-type results, maximum generalized local connectivity, extremal problems, random graphs, multigraphs, relations with the Steiner tree packing problem and generalizations of connectivity. This book enables graduate students to understand and master a segment of graph theory and combinatorial optimization. Researchers in graph theory, combinatorics, combinatorial optimization, probability, computer science, discrete algorithms, complexity analysis, network design, and the information transferring models will find this book useful in their studies.

  1. Handbook of Brain Connectivity

    CERN Document Server

    Jirsa, Viktor K

    2007-01-01

    Our contemporary understanding of brain function is deeply rooted in the ideas of the nonlinear dynamics of distributed networks. Cognition and motor coordination seem to arise from the interactions of local neuronal networks, which themselves are connected in large scales across the entire brain. The spatial architectures between various scales inevitably influence the dynamics of the brain and thereby its function. But how can we integrate brain connectivity amongst these structural and functional domains? Our Handbook provides an account of the current knowledge on the measurement, analysis and theory of the anatomical and functional connectivity of the brain. All contributors are leading experts in various fields concerning structural and functional brain connectivity. In the first part of the Handbook, the chapters focus on an introduction and discussion of the principles underlying connected neural systems. The second part introduces the currently available non-invasive technologies for measuring struct...

  2. Modeling Structural Brain Connectivity

    DEFF Research Database (Denmark)

    Ambrosen, Karen Marie Sandø

    The human brain consists of a gigantic complex network of interconnected neurons. Together all these connections determine who we are, how we react and how we interpret the world. Knowledge about how the brain is connected can further our understanding of the brain’s structural organization, help...... improve diagnosis, and potentially allow better treatment of a wide range of neurological disorders. Tractography based on diffusion magnetic resonance imaging is a unique tool to estimate this “structural connectivity” of the brain non-invasively and in vivo. During the last decade, brain connectivity...... has increasingly been analyzed using graph theoretic measures adopted from network science and this characterization of the brain’s structural connectivity has been shown to be useful for the classification of populations, such as healthy and diseased subjects. The structural connectivity of the brain...

  3. Profiling cancer

    DEFF Research Database (Denmark)

    Ciro, Marco; Bracken, Adrian P; Helin, Kristian

    2003-01-01

    In the past couple of years, several very exciting studies have demonstrated the enormous power of gene-expression profiling for cancer classification and prediction of patient survival. In addition to promising a more accurate classification of cancer and therefore better treatment of patients......, gene-expression profiling can result in the identification of novel potential targets for cancer therapy and a better understanding of the molecular mechanisms leading to cancer....

  4. Sensing coral reef connectivity pathways from space

    KAUST Repository

    Raitsos, Dionysios E.; Brewin, Robert J. W.; Zhan, Peng; Dreano, Denis; Pradhan, Yaswant; Nanninga, Gerrit B.; Hoteit, Ibrahim

    2017-01-01

    Coral reefs rely on inter-habitat connectivity to maintain gene flow, biodiversity and ecosystem resilience. Coral reef communities of the Red Sea exhibit remarkable genetic homogeneity across most of the Arabian Peninsula coastline, with a genetic break towards the southern part of the basin. While previous studies have attributed these patterns to environmental heterogeneity, we hypothesize that they may also emerge as a result of dynamic circulation flow; yet, such linkages remain undemonstrated. Here, we integrate satellite-derived biophysical observations, particle dispersion model simulations, genetic population data and ship-borne in situ profiles to assess reef connectivity in the Red Sea. We simulated long-term (>20 yrs.) connectivity patterns driven by remotely-sensed sea surface height and evaluated results against estimates of genetic distance among populations of anemonefish, Amphiprion bicinctus, along the eastern Red Sea coastline. Predicted connectivity was remarkably consistent with genetic population data, demonstrating that circulation features (eddies, surface currents) formulate physical pathways for gene flow. The southern basin has lower physical connectivity than elsewhere, agreeing with known genetic structure of coral reef organisms. The central Red Sea provides key source regions, meriting conservation priority. Our analysis demonstrates a cost-effective tool to estimate biophysical connectivity remotely, supporting coastal management in data-limited regions.

  5. Sensing coral reef connectivity pathways from space

    KAUST Repository

    Raitsos, Dionysios E.

    2017-08-18

    Coral reefs rely on inter-habitat connectivity to maintain gene flow, biodiversity and ecosystem resilience. Coral reef communities of the Red Sea exhibit remarkable genetic homogeneity across most of the Arabian Peninsula coastline, with a genetic break towards the southern part of the basin. While previous studies have attributed these patterns to environmental heterogeneity, we hypothesize that they may also emerge as a result of dynamic circulation flow; yet, such linkages remain undemonstrated. Here, we integrate satellite-derived biophysical observations, particle dispersion model simulations, genetic population data and ship-borne in situ profiles to assess reef connectivity in the Red Sea. We simulated long-term (>20 yrs.) connectivity patterns driven by remotely-sensed sea surface height and evaluated results against estimates of genetic distance among populations of anemonefish, Amphiprion bicinctus, along the eastern Red Sea coastline. Predicted connectivity was remarkably consistent with genetic population data, demonstrating that circulation features (eddies, surface currents) formulate physical pathways for gene flow. The southern basin has lower physical connectivity than elsewhere, agreeing with known genetic structure of coral reef organisms. The central Red Sea provides key source regions, meriting conservation priority. Our analysis demonstrates a cost-effective tool to estimate biophysical connectivity remotely, supporting coastal management in data-limited regions.

  6. Connected motorcycle system performance.

    Science.gov (United States)

    2016-01-15

    This project characterized the performance of Connected Vehicle Systems (CVS) on motorcycles based on two key components: global positioning and wireless communication systems. Considering that Global Positioning System (GPS) and 5.9 GHz Dedicated Sh...

  7. Connected vehicle applications : environment.

    Science.gov (United States)

    2016-01-01

    The U.S. Department of Transportation has developed a number of connected vehicle environmental applications, including the Applications for the Environment Real-Time Information Synthesis (AERIS) research program applications and road weather applic...

  8. Connected vehicle applications : safety.

    Science.gov (United States)

    2016-01-01

    Connected vehicle safety applications are designed to increase situational awareness : and reduce or eliminate crashes through vehicle-to-infrastructure, vehicle-to-vehicle, : and vehicle-to-pedestrian data transmissions. Applications support advisor...

  9. IDRC Connect User Guide

    International Development Research Centre (IDRC) Digital Library (Canada)

    Kristina Kamichaitis

    Once an account has been created by IDRC staff, you will receive .... content label in the table to access additional information. Table 3: ... One of the primary functions of IDRC Connect is to enable efficient and automated submission of final.

  10. Connected vehicles and cybersecurity.

    Science.gov (United States)

    2016-01-01

    Connected vehicles are a next-generation technology in vehicles and in infrastructure that will make travel safer, cleaner, and more efficient. The advanced wireless technology enables vehicles to share and communicate information with each other and...

  11. Hydrologically Connected Road Segments

    Data.gov (United States)

    Vermont Center for Geographic Information — Link it ArcGIS Item is HERE.The connectivity layer was created to assist municipalities in preparing for the forthcoming DEC Municipal Roads General Permit in 2018....

  12. IDRC Connect User Guide

    International Development Research Centre (IDRC) Digital Library (Canada)

    Kristina Kamichaitis

    IDRC Extranet home page, which is an umbrella for a number of applications available to IDRC external users. ... IDRC Connect is not formatted for mobile users. ..... Thesis. • Training Material. • Website. • Working Paper. • Workshop Report.

  13. [Connective tissue and inflammation].

    Science.gov (United States)

    Jakab, Lajos

    2014-03-23

    The author summarizes the structure of the connective tissues, the increasing motion of the constituents, which determine the role in establishing the structure and function of that. The structure and function of the connective tissue are related to each other in the resting as well as inflammatory states. It is emphasized that cellular events in the connective tissue are part of the defence of the organism, the localisation of the damage and, if possible, the maintenance of restitutio ad integrum. The organism responds to damage with inflammation, the non specific immune response, as well as specific, adaptive immunity. These processes are located in the connective tissue. Sterile and pathogenic inflammation are relatively similar processes, but inevitable differences are present, too. Sialic acids and glycoproteins containing sialic acids have important roles, and the role of Siglecs is also highlighted. Also, similarities and differences in damages caused by pathogens and sterile agents are briefly summarized. In addition, the roles of adhesion molecules linked to each other, and the whole event of inflammatory processes are presented. When considering practical consequences it is stressed that the structure (building up) of the organism and the defending function of inflammation both have fundamental importance. Inflammation has a crucial role in maintaining the integrity and the unimpaired somato-psychological state of the organism. Thus, inflammation serves as a tool of organism identical with the natural immune response, inseparably connected with the specific, adaptive immune response. The main events of the inflammatory processes take place in the connective tissue.

  14. Quick connect fastener

    Science.gov (United States)

    Weddendorf, Bruce

    1994-01-01

    A quick connect fastener and method of use is presented wherein the quick connect fastener is suitable for replacing available bolts and screws, the quick connect fastener being capable of installation by simply pushing a threaded portion of the connector into a member receptacle hole, the inventive apparatus being comprised of an externally threaded fastener having a threaded portion slidably mounted upon a stud or bolt shaft, wherein the externally threaded fastener portion is expandable by a preloaded spring member. The fastener, upon contact with the member receptacle hole, has the capacity of presenting cylindrical threads of a reduced diameter for insertion purposes and once inserted into the receiving threads of the receptacle member hole, are expandable for engagement of the receptacle hole threads forming a quick connect of the fastener and the member to be fastened, the quick connect fastener can be further secured by rotation after insertion, even to the point of locking engagement, the quick connect fastener being disengagable only by reverse rotation of the mated thread engagement.

  15. Connectivity in river deltas

    Science.gov (United States)

    Passalacqua, P.; Hiatt, M. R.; Sendrowski, A.

    2016-12-01

    Deltas host approximately half a billion people and are rich in ecosystem diversity and economic resources. However, human-induced activities and climatic shifts are significantly impacting deltas around the world; anthropogenic disturbance, natural subsidence, and eustatic sea-level rise are major causes of threat to deltas and in many cases have compromised their safety and sustainability, putting at risk the people that live on them. In this presentation, I will introduce a framework called Delta Connectome for studying connectivity in river deltas based on different representations of a delta as a network. Here connectivity indicates both physical connectivity (how different portions of the system interact with each other) as well as conceptual (pathways of process coupling). I will explore several network representations and show how quantifying connectivity can advance our understanding of system functioning and can be used to inform coastal management and restoration. From connectivity considerations, the delta emerges as a leaky network that evolves over time and is characterized by continuous exchanges of fluxes of matter, energy, and information. I will discuss the implications of connectivity on delta functioning, land growth, and potential for nutrient removal.

  16. Connectable solar air collectors

    Energy Technology Data Exchange (ETDEWEB)

    Oestergaard Jensen, S.; Bosanac, M.

    2002-02-01

    The project has proved that it is possible to manufacture solar air collector panels, which in an easy way can be connected into large collector arrays with integrated ducting without loss of efficiency. The developed connectable solar air collectors are based on the use of matrix absorbers in the form of perforated metal sheets. Three interconnected solar air collectors of the above type - each with an transparent area of approx. 3 m{sup 2} - was tested and compared with parallel tests on two single solar air collectors also with a transparent area of approx. 3 m{sup 2} One of the single solar air collectors has an identical absorber as the connectable solar air collectors while the absorber of the other single solar air collector was a fibre cloth. The efficiency of the three solar air collectors proved to be almost identical in the investigated range of mass flow rates and temperature differences. The solar air collectors further proved to be very efficient - as efficient as the second most efficient solar air collectors tested in the IEA task 19 project Solar Air Systems. Some problems remain although to be solved: the pressure drop across especially the connectable solar air collectors is too high - mainly across the inlets of the solar air collectors. It should, however, be possible to considerably reduce the pressure losses with a more aerodynamic design of the inlet and outlet of the solar air collectors; The connectable solar air collectors are easy connectable but the air tightness of the connections in the present form is not good enough. As leakage leads to lower efficiencies focus should be put on making the connections more air tight without loosing the easiness in connecting the solar air collectors. As a spin off of the project a simple and easy way to determine the efficiency of solar, air collectors for pre-heating of fresh air has been validated. The simple method of determining the efficiency has with success been compared with an advance method

  17. Profile of autoimmune connective tissue disorders in the University ...

    African Journals Online (AJOL)

    The major causes of mortality for the SLE patients were lupus nephritis, congestive cardiac failure and pulmonary hypertension, while death from systemic sclerosis was mostly linked to the renal crises. Rheumatoid factor was positive in 28 (93.3%), while Anti Neutrophilic Antibody was positive in 8 (26.6%) of the tested ...

  18. Connectivity and superconductivity

    CERN Document Server

    Rubinstein, Jacob

    2000-01-01

    The motto of connectivity and superconductivity is that the solutions of the Ginzburg--Landau equations are qualitatively influenced by the topology of the boundaries, as in multiply-connected samples. Special attention is paid to the "zero set", the set of the positions (also known as "quantum vortices") where the order parameter vanishes. The effects considered here usually become important in the regime where the coherence length is of the order of the dimensions of the sample. It takes the intuition of physicists and the awareness of mathematicians to find these new effects. In connectivity and superconductivity, theoretical and experimental physicists are brought together with pure and applied mathematicians to review these surprising results. This volume is intended to serve as a reference book for graduate students and researchers in physics or mathematics interested in superconductivity, or in the Schrödinger equation as a limiting case of the Ginzburg--Landau equations.

  19. A super soliton connection

    International Nuclear Information System (INIS)

    Gurses, M.; Oguz, O.

    1985-07-01

    Integrable super non-linear classical partial differential equations are considered. A super s1(2,R) algebra valued connection 1-form is constructed. It is shown that curvature 2-form of this super connection vanishes by virtue of the integrable super equations of motion. A super extension of the AKNS scheme is presented and a class of super extension of the Lax hierarchy and super non-linear Schroedinger equation are found. O(N) extension and the Baecklund transformations of the above super equations are also considered. (author)

  20. Connecting textual segments

    DEFF Research Database (Denmark)

    Brügger, Niels

    2017-01-01

    history than just the years of the emergence of the web, the chapter traces the history of how segments of text have deliberately been connected to each other by the use of specific textual and media features, from clay tablets, manuscripts on parchment, and print, among others, to hyperlinks on stand......In “Connecting textual segments: A brief history of the web hyperlink” Niels Brügger investigates the history of one of the most fundamental features of the web: the hyperlink. Based on the argument that the web hyperlink is best understood if it is seen as another step in a much longer and broader...

  1. Best connected rectangular arrangements

    Directory of Open Access Journals (Sweden)

    Krishnendra Shekhawat

    2016-03-01

    Full Text Available It can be found quite often in the literature that many well-known architects have employed either the golden rectangle or the Fibonacci rectangle in their works. On contrary, it is rare to find any specific reason for using them so often. Recently, Shekhawat (2015 proved that the golden rectangle and the Fibonacci rectangle are one of the best connected rectangular arrangements and this may be one of the reasons for their high presence in architectural designs. In this work we present an algorithm that generates n-4 best connected rectangular arrangements so that the proposed solutions can be further used by architects for their designs.

  2. Secondary maxima in ozone profiles

    Directory of Open Access Journals (Sweden)

    R. Lemoine

    2004-01-01

    Full Text Available Ozone profiles from balloon soundings as well as SAGEII ozone profiles were used to detect anomalous large ozone concentrations of ozone in the lower stratosphere. These secondary ozone maxima are found to be the result of differential advection of ozone-poor and ozone-rich air associated with Rossby wave breaking events. The frequency and intensity of secondary ozone maxima and their geographical distribution is presented. The occurrence and amplitude of ozone secondary maxima is connected to ozone variability and trend at Uccle and account for a large part of the total ozone and lower stratospheric ozone variability.

  3. Connections among quantum logics

    International Nuclear Information System (INIS)

    Lock, P.F.; Hardegree, G.M.

    1985-01-01

    This paper gives a brief introduction to the major areas of work in quantum event logics: manuals (Foulis and Randall) and semi-Boolean algebras (Abbott). The two theories are compared, and the connection between quantum event logics and quantum propositional logics is made explicit. In addition, the work on manuals provides us with many examples of results stated in Part I. (author)

  4. Connectivity measures: a review

    Czech Academy of Sciences Publication Activity Database

    Kindlmann, Pavel; Burel, F.

    2008-01-01

    Roč. 23, č. 1 (2008), s. 879-890 ISSN 0921-2973 R&D Projects: GA MŠk LC06073; GA AV ČR(CZ) IAA6087301 Institutional research plan: CEZ:AV0Z60870520 Keywords : Conservation biology * Habitat fragmentation * Landscape connectivity * Measures * Species extinction Subject RIV: EH - Ecology, Behaviour Impact factor: 2.453, year: 2008

  5. Clip, connect, clone

    DEFF Research Database (Denmark)

    Fujima, Jun; Lunzer, Aran; Hornbæk, Kasper

    2010-01-01

    using three mechanisms: clipping of input and result elements from existing applications to form cells on a spreadsheet; connecting these cells using formulas, thus enabling result transfer between applications; and cloning cells so that multiple requests can be handled side by side. We demonstrate...

  6. A Connective Pedagogy.

    Science.gov (United States)

    Goral, Mary

    2000-01-01

    Our increasingly hurried lifestyle, changes in family structure, and intense economic pressures place stress on children and families. Waldorf education provides an educational environment that alleviates this stress through a connective pedagogy that encompasses continuity of people, curriculum, and instruction; a reverence and respect for the…

  7. Connected vehicle application : safety.

    Science.gov (United States)

    2015-01-01

    Connected vehicle safety applications are designed to increase situational awareness : and reduce or eliminate crashes through vehicle-to-infrastructure (V2I), vehicle-to-vehicle (V2V), and vehicle-to-pedestrian (V2P) data transmissions. Applications...

  8. Mathematics Connection: Editorial Policies

    African Journals Online (AJOL)

    Focus and Scope. MATHEMATICS CONNECTION aims at providing a forum to promote the development of Mathematics Education in Ghana. Articles that seek to enhance the teaching and/or learning of mathematics at all levels of the educational system are welcome ...

  9. Making the Connection

    Science.gov (United States)

    Perna, Mark C.

    2006-01-01

    Enrollment marketing is not just about enrollment; it is about creating relationships and serving one's community or target audience for many years. In this article, the author states that the first step in building such relationships is making a connection, and that is what effective marketing is all about. Administrators, teachers and critical…

  10. Connecting numeric models

    International Nuclear Information System (INIS)

    Caremoli, C.; Erhard, P.

    1996-01-01

    Computerized simulation uses calculation codes whose validation is reliable. Reactor simulators should take greater advantage of latest computer technology impact, in particular in the field of parallel processing. Instead of creating more global simulation codes whose validation might be a problem, connecting several existing codes should be a promising solution. (D.L.). 3 figs

  11. From connection to customer

    International Nuclear Information System (INIS)

    Milatz, H.; Soeters, R.

    2001-01-01

    Energy companies can no longer be certain that a customer today will remain a customer tomorrow. They have to work hard to achieve that. They are going from thinking in terms of connections to pampering their customers. Good Customer Relationship Management is a way to achieve a competitive advantage. The whole organisation has to adapt, particularly the customer orientation of employees

  12. Mapping functional connectivity

    Science.gov (United States)

    Peter Vogt; Joseph R. Ferrari; Todd R. Lookingbill; Robert H. Gardner; Kurt H. Riitters; Katarzyna Ostapowicz

    2009-01-01

    An objective and reliable assessment of wildlife movement is important in theoretical and applied ecology. The identification and mapping of landscape elements that may enhance functional connectivity is usually a subjective process based on visual interpretations of species movement patterns. New methods based on mathematical morphology provide a generic, flexible,...

  13. IDRC Connect User Guide

    International Development Research Centre (IDRC) Digital Library (Canada)

    Kristina Kamichaitis

    2 Jul 2015 ... IDRC Connect contribuye a la aplicación de la Política de Acceso abierto de IDRC facilitando ..... Tesis. • Material de capacitación. • Sitio web. • Documento de trabajo ..... incluir planes de estudios, metodologías y manuales.

  14. Connecting the Production Multiple

    DEFF Research Database (Denmark)

    Lichen, Alex Yu; Mouritsen, Jan

    &OP process itself is a fluid object, but there is still possibility to organise the messy Production. There are connections between the Production multiple and the managerial technology fluid. The fluid enacted the multiplicity of Production thus making it more difficult to be organised because there were...... in opposite directions. They are all part of the fluid object. There is no single chain of circulating references that makes the object a matter of fact. Accounting fluidity means that references drift back and forth and enact new realities also connected to the chain. In this setting future research may......This paper is about objects. It follows post ANT trajectories and finds that objects are multiple and fluid. Extant classic ANT inspired accounting research largely sees accounting inscriptions as immutable mobiles. Although multiplicity of objects upon which accounting acts has been explored...

  15. Evaluation of 604 Connect

    OpenAIRE

    Ladner, S.; Ihnat, M.

    2000-01-01

    The Vancouver Community Network (VCN) is a not-for-profit Internet Service Provider (ISP), based on the “freenet” model of public Internet access. As a VolNet delivery agency, VCN committed to providing participating organizations with the following: (1) A communications protocol, (2) Internet Access, (3) Computer Equipment, (4) Training, and (5) Technical Support. In April 1999, VCN began receiving applications from non-profit organizations for its 604 Connect program, so named for the 604 t...

  16. Energy storage connection system

    Science.gov (United States)

    Benedict, Eric L.; Borland, Nicholas P.; Dale, Magdelena; Freeman, Belvin; Kite, Kim A.; Petter, Jeffrey K.; Taylor, Brendan F.

    2012-07-03

    A power system for connecting a variable voltage power source, such as a power controller, with a plurality of energy storage devices, at least two of which have a different initial voltage than the output voltage of the variable voltage power source. The power system includes a controller that increases the output voltage of the variable voltage power source. When such output voltage is substantially equal to the initial voltage of a first one of the energy storage devices, the controller sends a signal that causes a switch to connect the variable voltage power source with the first one of the energy storage devices. The controller then causes the output voltage of the variable voltage power source to continue increasing. When the output voltage is substantially equal to the initial voltage of a second one of the energy storage devices, the controller sends a signal that causes a switch to connect the variable voltage power source with the second one of the energy storage devices.

  17. Cutter Connectivity Bandwidth Study

    Science.gov (United States)

    2002-10-01

    The goal of this study was to determine how much bandwidth is required for cutters to meet emerging data transfer requirements. The Cutter Connectivity Business Solutions Team with guidance front the Commandant's 5 Innovation Council sponsored this study. Today, many Coast Guard administrative and business functions are being conducted via electronic means. Although our larger cutters can establish part-time connectivity using commercial satellite communications (SATCOM) while underway, there are numerous complaints regarding poor application performance. Additionally, smaller cutters do not have any standard means of underway connectivity. The R&D study shows the most important factor affecting web performance and enterprise applications onboard cutters was latency. Latency describes the time it takes the signal to reach the satellite and come back down through space. The latency due to use of higher orbit satellites is causing poor application performance and inefficient use of expensive SATCOM links. To improve performance, the CC must, (1) reduce latency by using alternate communications links such as low-earth orbit satellites, (2) tailor applications to the SATCOM link and/or (3) optimize protocols used for data communication to minimize time required by present applications to establish communications between the user and the host systems.

  18. Paper, Profile, Petrarch

    DEFF Research Database (Denmark)

    Foote, Jonathan

    2018-01-01

    , the antique lexicon). By working them out together on the same sheet, the boundaries erode between whittling lines of poetry and carving blocks of stone. Unlike previous attempts to connect Michelangelo's architecture and poetry, this paper focuses on the materiality of the paper as a meeting point between...... the question of what might be discovered by looking closer at these three paper modani (Corpus 536, 538, 539). The verses on the modani are merely fragments and revisions, part of a lineage of multiple and incomplete sources. At the same time, as 1:1 scaled templates, the modani empowered in a unique way...... Michelangelo's well-known propensity toward the fragmentation and re-assembly of the profile line. What emerges is how the paper enabled parallel processes of iteration, cutting and substitution, each operating within rather strict formal boundaries (for the poem, the Petrarchan sonnet; for the architecture...

  19. Finding significantly connected voxels based on histograms of connection strengths

    DEFF Research Database (Denmark)

    Kasenburg, Niklas; Pedersen, Morten Vester; Darkner, Sune

    2016-01-01

    We explore a new approach for structural connectivity based segmentations of subcortical brain regions. Connectivity based segmentations are usually based on fibre connections from a seed region to predefined target regions. We present a method for finding significantly connected voxels based...... on the distribution of connection strengths. Paths from seed voxels to all voxels in a target region are obtained from a shortest-path tractography. For each seed voxel we approximate the distribution with a histogram of path scores. We hypothesise that the majority of estimated connections are false-positives...... and that their connection strength is distributed differently from true-positive connections. Therefore, an empirical null-distribution is defined for each target region as the average normalized histogram over all voxels in the seed region. Single histograms are then tested against the corresponding null...

  20. The Berry's connection

    International Nuclear Information System (INIS)

    Le Tourneux, J.

    1989-01-01

    A course on the Berry's connection is presented. The main steps leading to the Berry's discovery are reviewed and the obtained equations are examined. Some applications of Berry's formulation are presented. They include diatomic molecules, dipole-quadrupole interaction in spherical mucleus and diabolic pair transfer. The experimental results presented are the spectrum of the Na 3 molecule, the propagation of photons in an helical optical fiber and the neutron spin rotation. Non-abelian problems and the Aharonow-Anandan phase are discussed [fr

  1. The CONNECT project

    DEFF Research Database (Denmark)

    Assaf, Yaniv; Alexander, Daniel C; Jones, Derek K

    2013-01-01

    Of Neuroimagers for the Non-invasive Exploration of brain Connectivity and Tracts) project aimed to combine tractography and micro-structural measures of the living human brain in order to obtain a better estimate of the connectome, while also striving to extend validation of these measurements. This paper...... summarizes the project and describes the perspective of using micro-structural measures to study the connectome.......In recent years, diffusion MRI has become an extremely important tool for studying the morphology of living brain tissue, as it provides unique insights into both its macrostructure and microstructure. Recent applications of diffusion MRI aimed to characterize the structural connectome using...

  2. Skeletal muscle connective tissue

    DEFF Research Database (Denmark)

    Brüggemann, Dagmar Adeline

    in the structure of fibrous collagen and myofibers at high-resolution. The results demonstrate that the collagen composition in the extra cellular matrix of Gadus morhua fish muscle is much more complex than previously anticipated, as it contains type III, IV, V  and VI collagen in addition to type I. The vascular....... Consequently, functional structures, ensuring "tissue maintenance" must form a major role of connective tissue, in addition that is to the force transmitting structures one typically finds in muscle. Vascular structures have also been shown to change their mechanical properties with age and it has been shown...

  3. Conformally connected universes

    International Nuclear Information System (INIS)

    Cantor, M.; Piran, T.

    1983-01-01

    A well-known difficulty associated with the conformal method for the solution of the general relativistic Hamiltonian constraint is the appearance of an aphysical ''bag of gold'' singularity at the nodal surface of the conformal factor. This happens whenever the background Ricci scalar is too large. Using a simple model, it is demonstrated that some of these singular solutions do have a physical meaning, and that these can be considered as initial data for Universe containing black holes, which are connected, in a conformally nonsingular way with each other. The relation between the ADM mass and the horizon area in this solution supports the cosmic censorship conjecture. (author)

  4. Heritable Disorders of Connective Tissue

    Science.gov (United States)

    ... Home Health Topics English Español Heritable Disorders of Connective Tissue Basics In-Depth Download Download EPUB Download PDF ... they? Points To Remember About Heritable Disorders of Connective Tissue There are more than 200 heritable disorders that ...

  5. LHCb connects its pipes

    CERN Multimedia

    2006-01-01

    Two weeks ago the first beryllium section of the LHCb beam vacuum chamber was installed. This three-day operation, after requiring lengthy preparation work, demanded patience and precision as the first of four sections of the beampipe was connected to the vertex locator (VeLo) vacuum vessel. The AT-VAC Group with the collaboration of PH/LBD, including Gloria Corti, Tatsuya Nakada, Patrice Mermet, Delios Ramos, Frans Mul, Bruno Versollato, Bernard Corajod, and Raymond Veness. (Not pictured: Adriana Rossi and Laurent Bouvet) This first installed section is composed of a nearly two-metre long conical tube of one-millimetre thick beryllium and of a thin spherical-shaped window, 800 millimeter diameter, made of an aluminum alloy, and has the appearance of a mushroom lying on its side. The window is connected to the conical part of the beampipe through an aluminum alloy bellow, which is needed to allow for mechanical alignment once the assembly is installed. Beryllium was chosen as the material for 12 m of the 19...

  6. Connective tissue activation. XVII

    International Nuclear Information System (INIS)

    Weiss, J.J.; Donakowski, C.; Anderson, B.; Meyers, S.; Castor, C.W.

    1980-01-01

    The platelet-derived connective tissue activating peptide (CTAP-III) has been shown to be an important factor stimulating the metabolism and proliferation of human connective tissue cell strains, including synovial tissue cells. The quantities of CTAP-III affecting the cellular changes and the amounts in various biologic fluids and tissues are small. The objectives of this study were to develop a radioimmunoassay (RIA) for CTAP-III and to ascertain the specificities of the anti-CTAP-III sera reagents. The antisera were shown not to cross-react with a number of polypeptide hormones. However, two other platelet proteins β-thromboglobulin and low affinity platelet factor-4, competed equally as well as CTAP-III for anti-CTAP-III antibodies in the RIA system. Thus, the three platelet proteins are similar or identical with respect to those portions of the molecules constituting the reactive antigenic determinants. The levels of material in normal human platelet-free plasma that inhibited anti-CTAP-III- 125 I-CTAP-III complex formation were determined to be 34+-13 (S.D.) ng/ml. (Auth.)

  7. Connectivity-oriented urban projects

    NARCIS (Netherlands)

    Philibert Petit, E.

    2006-01-01

    This thesis is about connections in the built environment, networked connections for the mobility of people at the smallest scale of the urban realm: the pedestrian scale. It deals with applications of the new science of networks as a tool for observation and assessment of connectivity in the urban

  8. Airport industry connectivity report: 2015

    NARCIS (Netherlands)

    Boonekamp, T.; Lieshout, R.; Burghouwt, G.

    2015-01-01

    This report is an update of the 'Airport Industry Connectivity Report 2004-2014'. It's focused on more recent developments and charting how Europe’s connectivity has evolved over the past 12 months. Airport connectivity is an increasingly discussed topic in European policy circles. With good reason.

  9. Connecting Architecture and Implementation

    Science.gov (United States)

    Buchgeher, Georg; Weinreich, Rainer

    Software architectures are still typically defined and described independently from implementation. To avoid architectural erosion and drift, architectural representation needs to be continuously updated and synchronized with system implementation. Existing approaches for architecture representation like informal architecture documentation, UML diagrams, and Architecture Description Languages (ADLs) provide only limited support for connecting architecture descriptions and implementations. Architecture management tools like Lattix, SonarJ, and Sotoarc and UML-tools tackle this problem by extracting architecture information directly from code. This approach works for low-level architectural abstractions like classes and interfaces in object-oriented systems but fails to support architectural abstractions not found in programming languages. In this paper we present an approach for linking and continuously synchronizing a formalized architecture representation to an implementation. The approach is a synthesis of functionality provided by code-centric architecture management and UML tools and higher-level architecture analysis approaches like ADLs.

  10. More features, greater connectivity.

    Science.gov (United States)

    Hunt, Sarah

    2015-09-01

    Changes in our political infrastructure, the continuing frailties of our economy, and a stark growth in population, have greatly impacted upon the perceived stability of the NHS. Healthcare teams have had to adapt to these changes, and so too have the technologies upon which they rely to deliver first-class patient care. Here Sarah Hunt, marketing co-ordinator at Aid Call, assesses how the changing healthcare environment has affected one of its fundamental technologies - the nurse call system, argues the case for wireless such systems in terms of what the company claims is greater adaptability to changing needs, and considers the ever-wider range of features and functions available from today's nurse call equipment, particularly via connectivity with both mobile devices, and ancillaries ranging from enuresis sensors to staff attack alert 'badges'.

  11. Practicing (Dis)connections

    DEFF Research Database (Denmark)

    The paper addresses the reciprocal notions of mobility and mobilisation in medical imaging practice, in view of the contingent and multiple character of the knowledge-practices involving such images – and their interpretation – within and across situated settings. Based on an ethnographically......’s development of in-house examination protocols as a consequence of its having replaced an older, pre-existing MRI scanner with a new model. This re-domestication of MRI as occasioned by the replacement scanner offers a range of sociomaterial and sociotechnical contingencies in the practice to come to light...... of the epistemic underpinnings which render, and condition, how connections are mediated across extended settings of practice (in the MRI unit, at interdisciplinary case conferences, and at other hospitals, etc.). This relational view allows for the heterogeneity entailed in the domestication of the MRI scanner...

  12. Crash Injury Risk Behavior in Adolescent Latino Males: The Power of Friends and Relational Connections

    OpenAIRE

    Vaca, Federico E.; Anderson, Craig L.

    2011-01-01

    The adolescent Latino male mortality profile is an anomaly when compared to an otherwise more favorable overall U.S. Latino population mortality profile. Motor vehicle crash fatalities bear a considerable proportion of mortality burden in this vulnerable population. Friend influence and relational connection are two contextual domains that may mediate crash injury risk behavior in these adolescents. Our study goal was to assess the role of friend influence over time and relational connections...

  13. TENTube: A Video-based Connection Tool Supporting Competence Development

    Directory of Open Access Journals (Sweden)

    Albert A Angehrn

    2008-07-01

    Full Text Available The vast majority of knowledge management initiatives fail because they do not take sufficiently into account the emotional, psychological and social needs of individuals. Only if users see real value for themselves will they actively use and contribute their own knowledge to the system, and engage with other users. Connection dynamics can make this easier, and even enjoyable, by connecting people and bringing them closer through shared experiences such as playing a game together. A higher connectedness of people to other people, and to relevant knowledge assets, will motivate them to participate more actively and increase system usage. In this paper, we describe the design of TENTube, a video-based connection tool we are developing to support competence development. TENTube integrates rich profiling and network visualization and navigation with agent-enhanced game-like connection dynamics.

  14. Mesoscale Connections Summer 2017

    Energy Technology Data Exchange (ETDEWEB)

    Kippen, Karen Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Bourke, Mark Andrew M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-06-21

    Our challenge derives from the fact that in metals or explosives grains, interfaces and defects control engineering performance in ways that are neither amenable to continuum codes (which fail to rigorously describe the heterogeneities derived from microstructure) nor computationally tractable to first principles atomistic calculations. This is a region called the mesoscale, which stands at the frontier of our desire to translate fundamental science insights into confidence in aging system performance over the range of extreme conditions relevant in a nuclear weapon. For dynamic problems, the phenomena of interest can require extremely good temporal resolutions. A shock wave traveling at 1000 m/s (or 1 mm/μs) passes through a grain with a diameter of 1 micron in a nanosecond (10-9 sec). Thus, to observe the mesoscale phenomena—such as dislocations or phase transformations—as the shock passes, temporal resolution better than picoseconds (10-12 sec) may be needed. As we anticipate the science challenges over the next decade, experimental insights on material performance at the micron spatial scale with picosecond temporal resolution—at the mesoscale— are a clear challenge. This is a challenge fit for Los Alamos in partnership with our sister labs and academia. Mesoscale Connections will draw attention to our progress as we tackle the mesoscale challenge. We hope you like it and encourage suggestions of content you are interested in.

  15. Transnational Connections and Multiple Belongings

    DEFF Research Database (Denmark)

    Galal, Lise Paulsen; Sparre, Sara Cathrine Lei

    With the purpose of presenting DIMECCE key findings, we in this paper present different aspects, potentials and challenges related to the Middle Eastern Christians transnational connections and multiple belonging. We distinguish between individual transnational connections and practices, such as ......, such as family relations, churches as transnational – or global – institutions, and other organisations and associations established to support politically, socially or culturally connections and development in the country or region of origin....

  16. Anonymous Connections and Onion Routing

    National Research Council Canada - National Science Library

    Syverson, Paul F; Goldschlag, David M; Reed, Michael G

    1997-01-01

    .... Unmodified Internet applications can use these anonymous connections by means of proxies. The proxies may also make communication anonymous by removing identifying information from the data stream...

  17. Interstate Connections - CEHC [ds619

    Data.gov (United States)

    California Natural Resource Agency — The California Department of Transportation (Caltrans) and California Department of Fish and Game (CDFG) commissioned the California Essential Habitat Connectivity...

  18. Systemic connective tissue features in women with fibromuscular dysplasia.

    Science.gov (United States)

    O'Connor, Sarah; Kim, Esther Sh; Brinza, Ellen; Moran, Rocio; Fendrikova-Mahlay, Natalia; Wolski, Kathy; Gornik, Heather L

    2015-10-01

    Fibromuscular dysplasia (FMD) is a non-atherosclerotic disease associated with hypertension, headache, dissection, stroke, and aneurysm. The etiology is unknown but hypothesized to involve genetic and environmental components. Previous studies suggest a possible overlap of FMD with other connective tissue diseases that present with dissections and aneurysms. The aim of this study was to investigate the prevalence of connective tissue physical features in FMD. A total of 142 FMD patients were consecutively enrolled at a single referral center (97.9% female, 92.1% of whom had multifocal FMD). Data are reported for 139 female patients. Moderately severe myopia (29.1%), high palate (33.1%), dental crowding (29.7%), and early-onset arthritis (15.6%) were prevalent features. Classic connective features such as hypertelorism, cleft palate, and hypermobility were uncommon. The frequency of systemic connective tissue features was compared between FMD patients with a high vascular risk profile (having had ⩾1 dissection and/or ⩾2 aneurysms) and those with a standard vascular risk profile. A history of spontaneous pneumothorax (5.9% high risk vs 0% standard risk) and atrophic scarring (17.6% high risk vs 6.8% standard risk) were significantly more prevalent in the high risk group, pconnective tissue features such as high palate and pneumothorax were more prominent among FMD patients with a high vascular risk profile. © The Author(s) 2015.

  19. Family Connections: Building Connections among Home, School, and Community

    Science.gov (United States)

    Dikkers, Amy Garrett

    2013-01-01

    Recent research on parental involvement has explored connections between parental involvement in school and children's academic achievement. While many schools have active parent organizations and a base of parents who offer additional support, others struggle to make connections with their parents or community members. Even in places with active…

  20. Carl Sagan's Cosmic Connection

    Science.gov (United States)

    Sagan, Carl; Agel, Jerome

    2000-08-01

    Foreword Freeman Dyson; Personal reflections Ann Druyan; Preface; Part I. Cosmic Perspective: 1. A transitional animal; 2. The Unicorn of Cetus; 3. A message from earth; 4. A message to earth; 5. Experiments in utopias; 6. Chauvinism; 7. Space exploration as a human enterprise I. The scientific interest; 8. Space exploration as a human enterprise II. The public interest; 9. Space exploration as a human enterprise III. The historical interest; Part II. The Solar System: 10. On teaching the first grade; 11. 'The ancient and legendary Gods of old'; 12. The Venus detective story; 13. Venus is hell; 14. Science and 'intelligence'; 15. The moons of Barsoom; 16. The mountains of Mars I. Observations from earth; 17. The mountains of Mars II. Observations from space; 18. The canals of Mars; 19. The lost pictures of Mars; 20. The Ice Age and the cauldron; 21. Beginnings and ends of the Earth; 22. Terraforming the plants; 23. The exploration and utlization of the solar system; Part III. Beyond the Solar System: 24. Some of my best friends are dolphins; 25. 'Hello, central casting? Send me twenty extraterrestrials'; 26. The cosmic connection; 27. Extraterrestrial life: an idea whose time has come; 28. Has the Earth been visited?; 29. A search strategy for detecting extraterrestrial intelligence; 30. If we succeed 31. Cables, drums, and seashells; 32. The night freight to the stars; 33. Astroengineering; 34. Twenty questions: a classification of cosmic civilisations; 35. Galactic cultural exchanges; 36. A passage to elsewhere; 37. Starfolk I. A Fable; 38. Starfolk II. A future; 39. Starfolk III. The cosmic Cheshire cats; Epilog David Morrison; Index.

  1. Juno, The Cultural Connection

    Science.gov (United States)

    Clarke, Theodore

    2017-04-01

    After a 5 year journey and a billion miles cartwheeling through the vastness of space, the Juno spacecraft is in orbit about the planet Jupiter. With its suite of scientific instruments Juno scientists will catch a glimpse of the dawn of creation of our own solar system. Juno will address origins, asking for us all, Who am I? Where do I come from? But Juno is more than a space laboratory to study the planet Jupiter. Juno embodies the history of humankind's perception of the universe from Aristotle, Copernicus and Galileo, to the Juno spacecraft peering beneath the clouds of Jupiter. Juno embodies the literature of classical mythology and the timeless masterpieces of the Renaissance and Baroque periods in its very name. Juno carries to Jupiter small statuettes of the gods Jupiter and Juno and the scientist Galileo. Juno embodies cosmic visualization experiences through first ever movies of the moon occulting Earth (>2 million hits on YouTube) and the Galilean satellites orbiting about Jupiter (>1.8 million hits on You Tube). Juno embodies the stirring music of modern Greek composer Vangelis, the Orpheus of Juno, who provided the score for the movies of the moon occulting Earth and of the Galilean satellites orbiting Jupiter. Juno embodies down to Earth visualization experiences through trajectory models created of Juno's passage through the Earth-moon system and Juno's entire orbital mission at Jupiter. Juno is the embodiment of public engagement in its science in a fishbowl program. Indeed, because Juno is the embodiment of this remarkable union of science and technology, history and literature, music and art, and visualization and public engagement, Juno is truly an ambassador to the universe of a New Renaissance. In my paper, "Juno, the Cultural Connection," I will unveil a dimension of the Juno mission to the planet Jupiter that will appeal to a broad sector of the global public.

  2. Profile: Asian Americans

    Science.gov (United States)

    ... and Data > Minority Population Profiles > Asian American Profile: Asian Americans Asian American Profile (Map of the US with the top 10 states displaying the largest Asian American population according to the Census Bureau) CA - ...

  3. The Always-Connected Generation

    Science.gov (United States)

    Bull, Glen

    2010-01-01

    The Pew Internet and American Life project characterizes the millennials--the first generation to come of age in the new millennium--as the first "always-connected" generation. Significant aspects of culture are changing as a result. A changing world where all students are connected all the time has substantial educational implications. Despite…

  4. Partitioning graphs into connected parts

    NARCIS (Netherlands)

    Hof, van 't P.; Paulusma, D.; Woeginger, G.J.; Frid, A.; Morozov, A.S.; Rybalchenko, A.; Wagner, K.W.

    2009-01-01

    The 2-DISJOINT CONNECTED SUBGRAPHS problem asks if a given graph has two vertex-disjoint connected subgraphs containing pre-specified sets of vertices. We show that this problem is NP-complete even if one of the sets has cardinality 2. The LONGEST PATH CONTRACTIBILITY problem asks for the largest

  5. Connections for Small Vertex Models

    Indian Academy of Sciences (India)

    This paper is a first attempt at calssifying connections on small vertex models i.e., commuting squares of the form displayed in (1.2) below. ... obtain necessary conditions for two such `model connections' in (2, ) to be ... Current Issue : Vol.

  6. Privacy and the Connected Society

    DEFF Research Database (Denmark)

    Sørensen, Lene Tolstrup; Khajuria, Samant; Skouby, Knud Erik

    The Vision of the 5G enabled connected society is highly based on the evolution and implementation of Internet of Things. This involves, amongst others, a significant raise in devices, sensors and communication in pervasive interconnections as well as cooperation amongst devices and entities across...... the society. Enabling the vision of the connected society, researchers point in the direction of security and privacy as areas to challenge the vision. By use of the Internet of Things reference model as well as the vision of the connected society, this paper identifies privacy of the individual with respect...... to three selected areas: Shopping, connected cars and online gaming. The paper concludes that privacy is a complexity within the connected society vision and that thee is a need for more privacy use cases to shed light on the challenge....

  7. Deconstructing white matter connectivity of human amygdala nuclei with thalamus and cortex subdivisions in vivo.

    Science.gov (United States)

    Abivardi, Aslan; Bach, Dominik R

    2017-08-01

    Structural alterations in long-range amygdala connections are proposed to crucially underlie several neuropsychiatric disorders. While progress has been made in elucidating the function of these connections, our understanding of their structure in humans remains sparse and non-systematic. Harnessing diffusion-weighted imaging and probabilistic tractography in humans, we investigate connections between two main amygdala nucleus groups, thalamic nuclei, and cortex. We first parcellated amygdala into deep (basolateral) and superficial (centrocortical) nucleus groups, and thalamus into six subregions, using previously established protocols based on connectivity. Cortex was parcellated based on T1-weighted images. We found substantial amygdala connections to thalamus, with different patterns for the two amygdala nuclei. Crucially, we describe direct subcortical connections between amygdala and paraventricular thalamus. Different from rodents but similar to non-human primates, these are more pronounced for basolateral than centrocortical amygdala. Substantial white-matter connectivity between amygdala and visual pulvinar is also more pronounced for basolateral amygdala. Furthermore, we establish detailed connectivity profiles for basolateral and centrocortical amygdala to cortical regions. These exhibit cascadic connections with sensory cortices as suggested previously based on tracer methods in non-human animals. We propose that the quantitative connectivity profiles provided here may guide future work on normal and pathological function of human amygdala. Hum Brain Mapp 38:3927-3940, 2017. © 2017 Wiley Periodicals, Inc. © 2017 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.

  8. A simple and robust method for connecting small-molecule drugs using gene-expression signatures

    Directory of Open Access Journals (Sweden)

    Gant Timothy W

    2008-06-01

    Full Text Available Abstract Background Interaction of a drug or chemical with a biological system can result in a gene-expression profile or signature characteristic of the event. Using a suitably robust algorithm these signatures can potentially be used to connect molecules with similar pharmacological or toxicological properties by gene expression profile. Lamb et al first proposed the Connectivity Map [Lamb et al (2006, Science 313, 1929–1935] to make successful connections among small molecules, genes, and diseases using genomic signatures. Results Here we have built on the principles of the Connectivity Map to present a simpler and more robust method for the construction of reference gene-expression profiles and for the connection scoring scheme, which importantly allows the valuation of statistical significance of all the connections observed. We tested the new method with two randomly generated gene signatures and three experimentally derived gene signatures (for HDAC inhibitors, estrogens, and immunosuppressive drugs, respectively. Our testing with this method indicates that it achieves a higher level of specificity and sensitivity and so advances the original method. Conclusion The method presented here not only offers more principled statistical procedures for testing connections, but more importantly it provides effective safeguard against false connections at the same time achieving increased sensitivity. With its robust performance, the method has potential use in the drug development pipeline for the early recognition of pharmacological and toxicological properties in chemicals and new drug candidates, and also more broadly in other 'omics sciences.

  9. Differential structural and resting state connectivity between insular subdivisions and other pain-related brain regions.

    Science.gov (United States)

    Wiech, K; Jbabdi, S; Lin, C S; Andersson, J; Tracey, I

    2014-10-01

    Functional neuroimaging studies suggest that the anterior, mid, and posterior division of the insula subserve different functions in the perception of pain. The anterior insula (AI) has predominantly been associated with cognitive-affective aspects of pain, while the mid and posterior divisions have been implicated in sensory-discriminative processing. We examined whether this functional segregation is paralleled by differences in (1) structural and (2) resting state connectivity and (3) in correlations with pain-relevant psychological traits. Analyses were restricted to the 3 insular subdivisions and other pain-related brain regions. Both type of analyses revealed largely overlapping results. The AI division was predominantly connected to the ventrolateral prefrontal cortex (structural and resting state connectivity) and orbitofrontal cortex (structural connectivity). In contrast, the posterior insula showed strong connections to the primary somatosensory cortex (SI; structural connectivity) and secondary somatosensory cortex (SII; structural and resting state connectivity). The mid insula displayed a hybrid connectivity pattern with strong connections with the ventrolateral prefrontal cortex, SII (structural and resting state connectivity) and SI (structural connectivity). Moreover, resting state connectivity revealed strong connectivity of all 3 subdivisions with the thalamus. On the behavioural level, AI structural connectivity was related to the individual degree of pain vigilance and awareness that showed a positive correlation with AI-amygdala connectivity and a negative correlation with AI-rostral anterior cingulate cortex connectivity. In sum, our findings show a differential structural and resting state connectivity for the anterior, mid, and posterior insula with other pain-relevant brain regions, which might at least partly explain their different functional profiles in pain processing. Copyright © 2014 The Authors. Published by Elsevier B.V. All

  10. The Solar Connections Observatory for Planetary Environments

    Science.gov (United States)

    Oliversen, Ronald J.; Harris, Walter M.; Oegerle, William R. (Technical Monitor)

    2002-01-01

    The NASA Sun-Earth Connection theme roadmap calls for comparative study of how the planets, comets, and local interstellar medium (LISM) interact with the Sun and respond to solar variability. Through such a study we advance our understanding of basic physical plasma and gas dynamic processes, thus increasing our predictive capabilities for the terrestrial, planetary, and interplanetary environments where future remote and human exploration will occur. Because the other planets have lacked study initiatives comparable to the terrestrial ITM, LWS, and EOS programs, our understanding of the upper atmospheres and near space environments on these worlds is far less detailed than our knowledge of the Earth. To close this gap we propose a mission to study {\\it all) of the solar interacting bodies in our planetary system out to the heliopause with a single remote sensing space observatory, the Solar Connections Observatory for Planetary Environments (SCOPE). SCOPE consists of a binocular EUV/FUV telescope operating from a remote, driftaway orbit that provides sub-arcsecond imaging and broadband medium resolution spectro-imaging over the 55-290 nm bandpass, and high (R>10$^{5}$ resolution H Ly-$\\alpha$ emission line profile measurements of small scale planetary and wide field diffuse solar system structures. A key to the SCOPE approach is to include Earth as a primary science target. From its remote vantage point SCOPE will be able to observe auroral emission to and beyond the rotational pole. The other planets and comets will be monitored in long duration campaigns centered when possible on solar opposition when interleaved terrestrial-planet observations can be used to directly compare the response of both worlds to the same solar wind stream and UV radiation field. Using a combination of observations and MHD models, SCOPE will isolate the different controlling parameters in each planet system and gain insight into the underlying physical processes that define the

  11. Properly colored connectivity of graphs

    CERN Document Server

    Li, Xueliang; Qin, Zhongmei

    2018-01-01

    A comprehensive survey of proper connection of graphs is discussed in this book with real world applications in computer science and network security. Beginning with a brief introduction, comprising relevant definitions and preliminary results, this book moves on to consider a variety of properties of graphs that imply bounds on the proper connection number. Detailed proofs of significant advancements toward open problems and conjectures are presented with complete references. Researchers and graduate students with an interest in graph connectivity and colorings will find this book useful as it builds upon fundamental definitions towards modern innovations, strategies, and techniques. The detailed presentation lends to use as an introduction to proper connection of graphs for new and advanced researchers, a solid book for a graduate level topics course, or as a reference for those interested in expanding and further developing research in the area.

  12. Connected vehicle pilot deployment program.

    Science.gov (United States)

    2014-01-01

    The U.S. Department of Transportations (USDOTs) connected vehicle research : program is a multimodal initiative to enable safe, interoperable, networked wireless : communications among vehicles, infrastructure, and personal communications : dev...

  13. Cybersecurity for Connected Diabetes Devices.

    Science.gov (United States)

    Klonoff, David C

    2015-04-16

    Diabetes devices are increasingly connected wirelessly to each other and to data-displaying reader devices. Threats to the accurate flow of information and commands may compromise the function of these devices and put their users at risk of health complications. Sound cybersecurity of connected diabetes devices is necessary to maintain confidentiality, integrity, and availability of the data and commands. Diabetes devices can be hacked by unauthorized agents and also by patients themselves to extract data that are not automatically provided by product software. Unauthorized access to connected diabetes devices has been simulated and could happen in reality. A cybersecurity standard designed specifically for connected diabetes devices will improve the safety of these products and increase confidence of users that the products will be secure. © 2015 Diabetes Technology Society.

  14. Functional Connectivity of Human Chewing

    Science.gov (United States)

    Quintero, A.; Ichesco, E.; Schutt, R.; Myers, C.; Peltier, S.; Gerstner, G.E.

    2013-01-01

    Mastication is one of the most important orofacial functions. The neurobiological mechanisms of masticatory control have been investigated in animal models, but less so in humans. This project used functional connectivity magnetic resonance imaging (fcMRI) to assess the positive temporal correlations among activated brain areas during a gum-chewing task. Twenty-nine healthy young-adults underwent an fcMRI scanning protocol while they chewed gum. Seed-based fcMRI analyses were performed with the motor cortex and cerebellum as regions of interest. Both left and right motor cortices were reciprocally functionally connected and functionally connected with the post-central gyrus, cerebellum, cingulate cortex, and precuneus. The cerebellar seeds showed functional connections with the contralateral cerebellar hemispheres, bilateral sensorimotor cortices, left superior temporal gyrus, and left cingulate cortex. These results are the first to identify functional central networks engaged during mastication. PMID:23355525

  15. Connecting and Networking for Schools

    Science.gov (United States)

    Resources for connecting and networking for schools through e-newsletters, finding school IAQ Champions and other EPA school programs such as Asthma, Energy Star, Clean School Bus USA, School Flag, etc.

  16. Visualizing neuronal network connectivity with connectivity pattern tables

    Directory of Open Access Journals (Sweden)

    Eilen Nordlie

    2010-01-01

    Full Text Available Complex ideas are best conveyed through well-designed illustrations. Up to now, computational neuroscientists have mostly relied on box-and-arrow diagrams of even complex neuronal networks, often using ad hoc notations with conflicting use of symbols from paper to paper. This significantly impedes the communication of ideas in neuronal network modeling. We present here Connectivity Pattern Tables (CPTs as a clutter-free visualization of connectivity in large neuronal networks containing two-dimensional populations of neurons. CPTs can be generated automatically from the same script code used to create the actual network in the NEST simulator. Through aggregation, CPTs can be viewed at different levels, providing either full detail or summary information. We also provide the open source ConnPlotter tool as a means to create connectivity pattern tables.

  17. MedlinePlus Connect: How it Works

    Science.gov (United States)

    ... Connect → How it Works URL of this page: https://medlineplus.gov/connect/howitworks.html MedlinePlus Connect: How ... will change.) Old URLs New URLs Web Application https://apps.nlm.nih.gov/medlineplus/services/mpconnect.cfm? ...

  18. MedlinePlus Connect in Use

    Science.gov (United States)

    ... MedlinePlus Connect in Use URL of this page: https://medlineplus.gov/connect/users.html MedlinePlus Connect in ... will change.) Old URLs New URLs Web Application https://apps.nlm.nih.gov/medlineplus/services/mpconnect.cfm? ...

  19. Brain Connectivity and Visual Attention

    Science.gov (United States)

    Parks, Emily L.

    2013-01-01

    Abstract Emerging hypotheses suggest that efficient cognitive functioning requires the integration of separate, but interconnected cortical networks in the brain. Although task-related measures of brain activity suggest that a frontoparietal network is associated with the control of attention, little is known regarding how components within this distributed network act together or with other networks to achieve various attentional functions. This review considers both functional and structural studies of brain connectivity, as complemented by behavioral and task-related neuroimaging data. These studies show converging results: The frontal and parietal cortical regions are active together, over time, and identifiable frontoparietal networks are active in relation to specific task demands. However, the spontaneous, low-frequency fluctuations of brain activity that occur in the resting state, without specific task demands, also exhibit patterns of connectivity that closely resemble the task-related, frontoparietal attention networks. Both task-related and resting-state networks exhibit consistent relations to behavioral measures of attention. Further, anatomical structure, particularly white matter pathways as defined by diffusion tensor imaging, places constraints on intrinsic functional connectivity. Lastly, connectivity analyses applied to investigate cognitive differences across individuals in both healthy and diseased states suggest that disconnection of attentional networks is linked to deficits in cognitive functioning, and in extreme cases, to disorders of attention. Thus, comprehensive theories of visual attention and their clinical translation depend on the continued integration of behavioral, task-related neuroimaging, and brain connectivity measures. PMID:23597177

  20. Random Interchange of Magnetic Connectivity

    Science.gov (United States)

    Matthaeus, W. H.; Ruffolo, D. J.; Servidio, S.; Wan, M.; Rappazzo, A. F.

    2015-12-01

    Magnetic connectivity, the connection between two points along a magnetic field line, has a stochastic character associated with field lines random walking in space due to magnetic fluctuations, but connectivity can also change in time due to dynamical activity [1]. For fluctuations transverse to a strong mean field, this connectivity change be caused by stochastic interchange due to component reconnection. The process may be understood approximately by formulating a diffusion-like Fokker-Planck coefficient [2] that is asymptotically related to standard field line random walk. Quantitative estimates are provided, for transverse magnetic field models and anisotropic models such as reduced magnetohydrodynamics. In heliospheric applications, these estimates may be useful for understanding mixing between open and close field line regions near coronal hole boundaries, and large latitude excursions of connectivity associated with turbulence. [1] A. F. Rappazzo, W. H. Matthaeus, D. Ruffolo, S. Servidio & M. Velli, ApJL, 758, L14 (2012) [2] D. Ruffolo & W. Matthaeus, ApJ, 806, 233 (2015)

  1. Continuously Connected With Mobile IP

    Science.gov (United States)

    2002-01-01

    Cisco Systems developed Cisco Mobile Networks, making IP devices mobile. With this innovation, a Cisco router and its connected IP devices can roam across network boundaries and connection types. Because a mobile user is able to keep the same IP address while roaming, a live IP connection can be maintained without interruption. Glenn Research Center jointly tested the technology with Cisco, and is working to use it on low-earth-orbiting research craft. With Cisco's Mobile Networks functionality now available in Cisco IOS Software release 12.2(4)T, the commercial advantages and benefits are numerous. The technology can be applied to public safety, military/homeland security, emergency management services, railroad and shipping systems, and the automotive industry. It will allow ambulances, police, firemen, and the U.S. Coast Guard to stay connected to their networks while on the move. In the wireless battlefield, the technology will provide rapid infrastructure deployment for U.S. national defense. Airline, train, and cruise passengers utilizing Cisco Mobile Networks can fly all around the world with a continuous Internet connection. Cisco IOS(R) Software is a registered trademark of Cisco Systems.

  2. HOPWA Performance Profiles

    Data.gov (United States)

    Department of Housing and Urban Development — HOPWA Performance Profiles are generated quarterly for all agencies receiving HOPWA formula or competitive grants. Performance Profiles are available at the national...

  3. Functional connectivity changes detected with magnetoencephalography after mild traumatic brain injury

    Directory of Open Access Journals (Sweden)

    Stavros I. Dimitriadis

    2015-01-01

    Full Text Available Mild traumatic brain injury (mTBI may affect normal cognition and behavior by disrupting the functional connectivity networks that mediate efficient communication among brain regions. In this study, we analyzed brain connectivity profiles from resting state Magnetoencephalographic (MEG recordings obtained from 31 mTBI patients and 55 normal controls. We used phase-locking value estimates to compute functional connectivity graphs to quantify frequency-specific couplings between sensors at various frequency bands. Overall, normal controls showed a dense network of strong local connections and a limited number of long-range connections that accounted for approximately 20% of all connections, whereas mTBI patients showed networks characterized by weak local connections and strong long-range connections that accounted for more than 60% of all connections. Comparison of the two distinct general patterns at different frequencies using a tensor representation for the connectivity graphs and tensor subspace analysis for optimal feature extraction showed that mTBI patients could be separated from normal controls with 100% classification accuracy in the alpha band. These encouraging findings support the hypothesis that MEG-based functional connectivity patterns may be used as biomarkers that can provide more accurate diagnoses, help guide treatment, and monitor effectiveness of intervention in mTBI.

  4. Implementation of Bluetooth serial port based profiles in embedded systems

    Science.gov (United States)

    Liu, Guanglei; Qiu, Zhengding; Wang, Quanping; Gao, Qiang

    2001-10-01

    Bluetooth is a new short-range wireless communication technology developing rapidly in recent years. Bluetooth software architecture consists of stack and profiles. Serial Port Profile (SPP) is an underlying profile that emulates RS232 serial cable connections between two peer devices. Based on SPP, Dial-up Networking (DUN) Profile establishes PPP connection with remote dial-up server, Fax Profile realizes document facsimile function and LAN Access Profile (LAP) provides local area network access service. When it comes to their implementation in embedded systems, there are several challenges such as memory consumption, code efficiency, code reliability, and code portability onto different OS and hardware platforms to be attacked. In this paper, we propose integrated software architecture after discussing the great similarities shared among the three SPP based profiles. Then implementation of the architecture is given, in which OS-dependent and OS-independent parts are clearly separated. Profile interfaces with stack and OS are specified respectively so that the three profiles as a whole can be ported onto various software and hardware platforms easily. As a result, policy of transplanting our implementation onto different platforms is addressed at the end of the paper.

  5. Hitchin's connection in metaplectic quantization

    DEFF Research Database (Denmark)

    Andersen, Jørgen Ellegaard; Gammelgaard, Niels Leth; Lauridsen, Magnus Roed

    2012-01-01

    We give a differential geometric construction of a connection, which we call the Hitchin connection, in the bundle of quantum Hilbert spaces arising from metaplectically corrected geometric quantization of a prequantizable, symplectic manifold, endowed with a rigid family of Kähler structures, all...... manifold in question. Furthermore, when we are in a setting similar to the moduli space, we give an explicit formula and show that this connection agrees with previous constructions....... of which give vanishing first Dolbeault cohomology groups. This generalizes work of both Hitchin, Scheinost and Schottenloher, and Andersen, since our construction does not need that the first Chern class is proportional to the class of the symplectic form, nor do we need compactness of the symplectic...

  6. Review on Cold-Formed Steel Connections

    Science.gov (United States)

    Tan, Cher Siang; Mohammad, Shahrin; Md Tahir, Mahmood; Shek, Poi Ngian

    2014-01-01

    The concept of cold-formed light steel framing construction has been widespread after understanding its structural characteristics with massive research works over the years. Connection serves as one of the important elements for light steel framing in order to achieve its structural stability. Compared to hot-rolled steel sections, cold-formed steel connections perform dissimilarity due to the thin-walled behaviour. This paper aims to review current researches on cold-formed steel connections, particularly for screw connections, storage rack connections, welded connections, and bolted connections. The performance of these connections in the design of cold-formed steel structures is discussed. PMID:24688448

  7. Semantic connections: exploring and manipulating connections in smart spaces

    NARCIS (Netherlands)

    Vlist, van der B.J.J.; Niezen, G.; Hu, J.; Feijs, L.M.G.

    2010-01-01

    In envisioned smart environments, enabled by ubiquitous computing technologies, electronic objects will be able to interconnect and interoperate. How will users of such smart environments make sense of the connections that are made and the information that is exchanged? This Internet of Things could

  8. Whole-brain functional connectivity predicted by indirect structural connections

    DEFF Research Database (Denmark)

    Røge, Rasmus; Ambrosen, Karen Marie Sandø; Albers, Kristoffer Jon

    2017-01-01

    Modern functional and diffusion magnetic resonance imaging (fMRI and dMRI) provide data from which macro-scale networks of functional and structural whole brain connectivity can be estimated. Although networks derived from these two modalities describe different properties of the human brain, the...

  9. Characterisation of connective tissue from the hypertrophic skeletal muscle of myostatin null mice.

    Science.gov (United States)

    Elashry, Mohamed I; Collins-Hooper, Henry; Vaiyapuri, Sakthivel; Patel, Ketan

    2012-06-01

    Myostatin is a potent inhibitor of muscle development. Genetic deletion of myostatin in mice results in muscle mass increase, with muscles often weighing three times their normal values. Contracting muscle transfers tension to skeletal elements through an elaborate connective tissue network. Therefore, the connective tissue of skeletal muscle is an integral component of the contractile apparatus. Here we examine the connective tissue architecture in myostatin null muscle. We show that the hypertrophic muscle has decreased connective tissue content compared with wild-type muscle. Secondly, we show that the hypertrophic muscle fails to show the normal increase in muscle connective tissue content during ageing. Therefore, genetic deletion of myostatin results in an increase in contractile elements but a decrease in connective tissue content. We propose a model based on the contractile profile of muscle fibres that reconciles this apparent incompatible tissue composition phenotype. © 2012 The Authors. Journal of Anatomy © 2012 Anatomical Society.

  10. Formal connections in deformation quantization

    DEFF Research Database (Denmark)

    Masulli, Paolo

    The field of this thesis is deformation quantization, and we consider mainly symplectic manifolds equipped with a star product. After reviewing basics in complex geometry, we introduce quantization, focusing on geometric quantization and deformation quantization. The latter is defined as a star...... characteristic class, and that formal connections form an affine space over the derivations of the star products. Moreover, if the parameter space for the family of star products is contractible, we obtain that any two flat formal connections are gauge equivalent via a self-equivalence of the family of star...

  11. Developing a Connective Feminine Discourse

    DEFF Research Database (Denmark)

    Rahbek, Ulla

    2015-01-01

    This paper discusses the work of the Australian writer and historian Drusilla Modjeska through a focus on the intersections between women‟s lives, love and art, which constitute the central triptych of Modjeska‟s writing. It argues that Modjeska's oeuvre unfolds a connective feminine discourse...... through a development of what the paper calls hinging tropes, discursive connectors that join life, love and art, such as weaving, folding and talking. That connective feminine discourse is indeed central to Modjeska‟s personal and sometimes idiosyncratic feminism...

  12. C-connected frame congruences

    Directory of Open Access Journals (Sweden)

    Dharmanand Baboolal

    2017-01-01

    Full Text Available We discuss the congruences $theta$ that are connected as  elements of the (totally disconnected congruence frame $CF L$,  and show that they are in a one-to-one correspondence with the completely prime elements of $L$, giving an explicit formula. Then we investigate those frames $L$ with enough connected congruences to cover the whole of $CF L$. They are, among others, shown to be $T_D$-spatial;  characteristics for some special cases (Boolean, linear, scattered and Noetherian are presented.

  13. Ekspert i undervisning - IRIS Connect

    DEFF Research Database (Denmark)

    Wullum, Annemette Heine; Eriksen, Frits Hedegaard

    Ekspert i undervisning – IRIS Connect Credoet bag de seneste års mange læreruddannelsesreformer har været, at flere og dybere kundskaber vil styrke de studerendes forudsætninger for at løse opgaverne i pædagogisk praksis. Et forhold, som bliver overset i forbindelse med uddannelsesreformerne, er...... praksis, og hvad ”effektiv” undervisning er. Hovedantagelserne bag projektet er, at de studerendes personbundne kundskaber kan synliggøres, at deres lægmandsopfattelser af, hvad ”effektiv” undervisning er, kan udfordres gennem analyser og drøftelser, og at brugen af IRIS Connects dataindsamlings- og...

  14. Finite connectivity attractor neural networks

    International Nuclear Information System (INIS)

    Wemmenhove, B; Coolen, A C C

    2003-01-01

    We study a family of diluted attractor neural networks with a finite average number of (symmetric) connections per neuron. As in finite connectivity spin glasses, their equilibrium properties are described by order parameter functions, for which we derive an integral equation in replica symmetric approximation. A bifurcation analysis of this equation reveals the locations of the paramagnetic to recall and paramagnetic to spin-glass transition lines in the phase diagram. The line separating the retrieval phase from the spin-glass phase is calculated at zero temperature. All phase transitions are found to be continuous

  15. Connectivity-based parcellation of the human orbitofrontal cortex.

    Science.gov (United States)

    Kahnt, Thorsten; Chang, Luke J; Park, Soyoung Q; Heinzle, Jakob; Haynes, John-Dylan

    2012-05-02

    The primate orbitofrontal cortex (OFC) is involved in reward processing, learning, and decision making. Research in monkeys has shown that this region is densely connected with higher sensory, limbic, and subcortical regions. Moreover, a parcellation of the monkey OFC into two subdivisions has been suggested based on its intrinsic anatomical connections. However, in humans, little is known about any functional subdivisions of the OFC except for a rather coarse medial/lateral distinction. Here, we used resting-state fMRI in combination with unsupervised clustering techniques to investigate whether OFC subdivisions can be revealed based on their functional connectivity profiles with other brain regions. Examination of different cluster solutions provided support for a parcellation into two parts as observed in monkeys, but it also highlighted a much finer hierarchical clustering of the orbital surface. Specifically, we identified (1) a medial, (2) a posterior-central, (3) a central, and (4-6) three lateral clusters spanning the anterior-posterior gradient. Consistent with animal tracing studies, these OFC clusters were connected to other cortical regions such as prefrontal, temporal, and parietal cortices but also subcortical areas in the striatum and the midbrain. These connectivity patterns provide important implications for identifying specific functional roles of OFC subdivisions for reward processing, learning, and decision making. Moreover, this parcellation schema can provide guidance to report results in future studies.

  16. White matter structural connectivity and episodic memory in early childhood.

    Science.gov (United States)

    Ngo, Chi T; Alm, Kylie H; Metoki, Athanasia; Hampton, William; Riggins, Tracy; Newcombe, Nora S; Olson, Ingrid R

    2017-12-01

    Episodic memory undergoes dramatic improvement in early childhood; the reason for this is poorly understood. In adults, episodic memory relies on a distributed neural network. Key brain regions that supporting these processes include the hippocampus, portions of the parietal cortex, and portions of prefrontal cortex, each of which shows different developmental profiles. Here we asked whether developmental differences in the axonal pathways connecting these regions may account for the robust gains in episodic memory in young children. Using diffusion weighted imaging, we examined whether white matter connectivity between brain regions implicated in episodic memory differed with age, and were associated with memory performance differences in 4- and 6-year-old children. Results revealed that white matter connecting the hippocampus to the inferior parietal lobule significantly predicted children's performance on episodic memory tasks. In contrast, variation in the white matter connecting the hippocampus to the medial prefrontal cortex did not relate to memory performance. These findings suggest that structural connectivity between the hippocampus and lateral parietal regions is relevant to the development of episodic memory. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  17. White matter structural connectivity and episodic memory in early childhood

    Directory of Open Access Journals (Sweden)

    Chi T. Ngo

    2017-12-01

    Full Text Available Episodic memory undergoes dramatic improvement in early childhood; the reason for this is poorly understood. In adults, episodic memory relies on a distributed neural network. Key brain regions that supporting these processes include the hippocampus, portions of the parietal cortex, and portions of prefrontal cortex, each of which shows different developmental profiles. Here we asked whether developmental differences in the axonal pathways connecting these regions may account for the robust gains in episodic memory in young children. Using diffusion weighted imaging, we examined whether white matter connectivity between brain regions implicated in episodic memory differed with age, and were associated with memory performance differences in 4- and 6-year-old children. Results revealed that white matter connecting the hippocampus to the inferior parietal lobule significantly predicted children’s performance on episodic memory tasks. In contrast, variation in the white matter connecting the hippocampus to the medial prefrontal cortex did not relate to memory performance. These findings suggest that structural connectivity between the hippocampus and lateral parietal regions is relevant to the development of episodic memory. Keywords: White matter, Memory development, Episodic memory, Diffusion weighted imaging

  18. Spectral backward radiation profile

    International Nuclear Information System (INIS)

    Kwon, Sung Duck; Lee, Keun Hyun; Kim, Bo Ra; Yoon, Suk Soo

    2004-01-01

    Ultrasonic backward radiation profile is frequency-dependent when incident region has deptional gradient of acoustical properties or multi-layers. Until now, we have measured the profiles of principal frequencies of used transducers so that it was not easy to understand the change of the frequency component and spectrum of backward radiation from the profile. We tried to measure the spectral backward radiation profiles using DFP(digital filer package) Lecroy DSO. The very big changes in the shape and pattern of spectral backward radiation profiles leads to the conclusion that this new try could be very effective tool to evaluate frequency dependent surface area.

  19. Art and the Cosmic Connection

    Science.gov (United States)

    Cobb, Whitney H.; Aiello, Monica Petty; Macdonald, Reeves; Asplund, Shari

    2014-01-01

    The interdisciplinary unit described in this article utilizes "Art and the Cosmic Connection," a free program conceived of by artists Monica and Tyler Aiello and developed by the artists, scientists, and educators through NASA's Discovery and New Frontiers Programs, to inspire learners to explore mysterious worlds in our solar…

  20. Reduced prefrontal connectivity in psychopathy.

    Science.gov (United States)

    Motzkin, Julian C; Newman, Joseph P; Kiehl, Kent A; Koenigs, Michael

    2011-11-30

    Linking psychopathy to a specific brain abnormality could have significant clinical, legal, and scientific implications. Theories on the neurobiological basis of the disorder typically propose dysfunction in a circuit involving ventromedial prefrontal cortex (vmPFC). However, to date there is limited brain imaging data to directly test whether psychopathy may indeed be associated with any structural or functional abnormality within this brain area. In this study, we employ two complementary imaging techniques to assess the structural and functional connectivity of vmPFC in psychopathic and non-psychopathic criminals. Using diffusion tensor imaging, we show that psychopathy is associated with reduced structural integrity in the right uncinate fasciculus, the primary white matter connection between vmPFC and anterior temporal lobe. Using functional magnetic resonance imaging, we show that psychopathy is associated with reduced functional connectivity between vmPFC and amygdala as well as between vmPFC and medial parietal cortex. Together, these data converge to implicate diminished vmPFC connectivity as a characteristic neurobiological feature of psychopathy.

  1. Connections in wood and foliage

    Science.gov (United States)

    Kevin T. Smith

    2009-01-01

    Trees are networked systems that capture energy, move massive amounts of water and material, and provide the setting for human society and for the lives of many associated organisms. Tree survival depends on making and breaking the right connections within these networks.

  2. The Hanze-India Connection

    NARCIS (Netherlands)

    Velthuijsen, Hugo

    2010-01-01

    Hanze India connection. Presentatie gehouden op 09-06-2010. Bestaat uit foto's. Op uitnodiging van KPN, sponsor van het lectoraat New Business & ICT, bezocht Hugo Velthuijsen een aantal steden in India. Het doel was om ter plekke een beeld te krijgen van de mogelijkheden van IT en Business

  3. Grouted Connections with Shear Keys

    DEFF Research Database (Denmark)

    Pedersen, Ronnie; Jørgensen, M. B.; Damkilde, Lars

    2012-01-01

    This paper presents a finite element model in the software package ABAQUS in which a reliable analysis of grouted pile-to-sleeve connections with shear keys is the particular purpose. The model is calibrated to experimental results and a consistent set of input parameters is estimated so that dif...... that different structural problems can be reproduced successfully....

  4. Tilting-connected symmetric algebras

    OpenAIRE

    Aihara, Takuma

    2010-01-01

    The notion of silting mutation was introduced by Iyama and the author. In this paper we mainly study silting mutation for self-injective algebras and prove that any representation-finite symmetric algebra is tilting-connected. Moreover we give some sufficient conditions for a Bongartz-type Lemma to hold for silting objects.

  5. The Histogram-Area Connection

    Science.gov (United States)

    Gratzer, William; Carpenter, James E.

    2008-01-01

    This article demonstrates an alternative approach to the construction of histograms--one based on the notion of using area to represent relative density in intervals of unequal length. The resulting histograms illustrate the connection between the area of the rectangles associated with particular outcomes and the relative frequency (probability)…

  6. Connecting Slope, Steepness, and Angles

    Science.gov (United States)

    Nagle, Courtney R.; Moore-Russo, Deborah

    2013-01-01

    All teachers, especially high school teachers, face the challenge of ensuring that students have opportunities to relate and connect the various representations and notions of mathematics concepts developed over the course of the pre-K-12 mathematics curriculum. NCTM's (2000) Representation Standard emphasizes the importance of students being…

  7. Isolating highly connected induced subgraphs

    DEFF Research Database (Denmark)

    Penev, Irena; Thomasse, Stephan; Trotignon, Nicolas

    2016-01-01

    We prove that any graph G of minimum degree greater than 2k(2) - 1 has a (k + 1)-connected induced subgraph H such that the number of vertices of H that have neighbors outside of H is at most 2k(2) - 1. This generalizes a classical result of Mader, which states that a high minimum degree implies ...

  8. Elementary Algebra Connections to Precalculus

    Science.gov (United States)

    Lopez-Boada, Roberto; Daire, Sandra Arguelles

    2013-01-01

    This article examines the attitudes of some precalculus students to solve trigonometric and logarithmic equations and systems using the concepts of elementary algebra. With the goal of enticing the students to search for and use connections among mathematical topics, they are asked to solve equations or systems specifically designed to allow…

  9. Connected Firms and Investor Myopia

    NARCIS (Netherlands)

    Ginglinger, Edith; Hébert, Camille; Renneboog, Luc

    2017-01-01

    Conglomerates, multinational corporations and business groups are non-exclusive forms of complex firms. Often organized as corporate networks, complex firms control a myriad of firms connected through ownership links. We investigate whether parent-subsidiary links within corporate networks enhance

  10. Indicators of Malicious SSL Connections

    NARCIS (Netherlands)

    Bortolameotti, Riccardo; Peter, Andreas; Everts, Maarten Hinderik; Bolzoni, D.

    2015-01-01

    Internet applications use SSL to provide data confidential- ity to communicating entities. The use of encryption in SSL makes it impossible to distinguish between benign and malicious connections as the content cannot be inspected. Therefore, we propose and evaluate a set of indicators for malicious

  11. Indicators of malicious SSL connections

    NARCIS (Netherlands)

    Bortolameotti, R.; Peter, A.; Everts, M.H.; Bolzoni, D.

    2015-01-01

    Internet applications use SSL to provide data confidentiality to communicating entities. The use of encryption in SSL makes it impossible to distinguish between benign and malicious connections as the content cannot be inspected. Therefore, we propose and evaluate a set of indicators for malicious

  12. Contact traction analysis for profile change during coining process

    International Nuclear Information System (INIS)

    Kim, Hyung Kyu; Yoon, Kyung Ho; Kang, Heung Seok; Song, Kee Nam

    2002-01-01

    Contact tractions are analysed in the case of the change in contact profile occurring during the coining process of a thin strip material. The changed profile is assumed as a concave circular arc in the central part of the contact region which is smoothly connected with convex circular arcs at both sides, referring to the actual measurement of the coined material. The profile is discretized and the known solutions of singular integral equations are used. Since the contact profile affects the contact traction and relevant tribological behaviour (e.g. wear) as well, an accurate definition of the profile is necessary in the analysis of material failure. Parametric study is conducted with the variation of the radii and distance of the arcs, which defines the height difference between the summits of the arcs. Considered is the contact profile, which can give the negligible variation of the traction in comparison with that before the coining process

  13. Connecting Leadership and Learning: Do Versatile Learners make Connective Leaders?

    OpenAIRE

    Jill L. Robinson

    2016-01-01

    Recent failures in leadership, suggest that creating better-quality leadership development programs is critical. In moving from theory to practice, this paper examined the relationship between learning style and leadership style which may enable us to move away from one-size-fits-all leadership development programs. Utilizing Kolb’s Experiential Learning Model and Connective Leadership theory, approximately 3600 college students were analyzed to discover whether versatility in learning styles...

  14. Connecting leadership and learning: Do versatile learners make connective leaders?

    OpenAIRE

    Robinson, Jill L.

    2016-01-01

    Recent failures in leadership, suggest that creating better-quality leadership development programs is critical. In moving from theory to practice, this paper examined the relationship between learning style and leadership style which may enable us to move away from one-size-fits-all leadership development programs. Utilizing Kolb’s Experiential Learning Model and Connective Leadership theory, approximately 3600 college students were analyzed to discover whether versatility in learning styles...

  15. Connecting Leadership and Learning: Do Versatile Learners make Connective Leaders?

    OpenAIRE

    Jill L. Robinson

    2016-01-01

    Abstract Recent failures in leadership, suggest that creating better-quality leadership development programs is critical. In moving from theory to practice, this paper examined the relationship between learning style and leadership style which may enable us to move away from one-size-fits-all leadership development programs. Utilizing Kolb’s Experiential Learning Model and Connective Leadership theory, approximately 3600 college students were analyzed to discover whether versatility in le...

  16. Default network connectivity as a vulnerability marker for obsessive compulsive disorder.

    Science.gov (United States)

    Peng, Z W; Xu, T; He, Q H; Shi, C Z; Wei, Z; Miao, G D; Jing, J; Lim, K O; Zuo, X N; Chan, R C K

    2014-05-01

    Aberrant functional connectivity within the default network is generally assumed to be involved in the pathophysiology of obsessive compulsive disorder (OCD); however, the genetic risk of default network connectivity in OCD remains largely unknown. Here, we systematically investigated default network connectivity in 15 OCD patients, 15 paired unaffected siblings and 28 healthy controls. We sought to examine the profiles of default network connectivity in OCD patients and their siblings, exploring the correlation between abnormal default network connectivity and genetic risk for this population. Compared with healthy controls, OCD patients exhibited reduced strength of default network functional connectivity with the posterior cingulate cortex (PCC), and increased functional connectivity in the right inferior frontal lobe, insula, superior parietal cortex and superior temporal cortex, while their unaffected first-degree siblings only showed reduced local connectivity in the PCC. These findings suggest that the disruptions of default network functional connectivity might be associated with family history of OCD. The decreased default network connectivity in both OCD patients and their unaffected siblings may serve as a potential marker of OCD.

  17. Nonrandom network connectivity comes in pairs

    Directory of Open Access Journals (Sweden)

    Felix Z. Hoffmann

    2017-02-01

    Full Text Available Overrepresentation of bidirectional connections in local cortical networks has been repeatedly reported and is a focus of the ongoing discussion of nonrandom connectivity. Here we show in a brief mathematical analysis that in a network in which connection probabilities are symmetric in pairs, Pij = Pji, the occurrences of bidirectional connections and nonrandom structures are inherently linked; an overabundance of reciprocally connected pairs emerges necessarily when some pairs of neurons are more likely to be connected than others. Our numerical results imply that such overrepresentation can also be sustained when connection probabilities are only approximately symmetric.

  18. On Data Transfers Over Wide-Area Dedicated Connections

    Energy Technology Data Exchange (ETDEWEB)

    Rao, Nageswara S. [ORNL; Liu, Qiang [ORNL

    2018-01-01

    Dedicated wide-area network connections are employed in big data and high-performance computing scenarios, since the absence of cross-traffic promises to make it easier to analyze and optimize data transfers over them. However, nonlinear transport dynamics and end-system complexity due to multi-core hosts and distributed file systems make these tasks surprisingly challenging. We present an overview of methods to analyze memory and disk file transfers using extensive measurements over 10 Gbps physical and emulated connections with 0–366 ms round trip times (RTTs). For memory transfers, we derive performance profiles of TCP and UDT throughput as a function of RTT, which show concave regions in contrast to entirely convex regions predicted by previous models. These highly desirable concave regions can be expanded by utilizing large buffers and more parallel flows. We also present Poincar´e maps and Lyapunov exponents of TCP and UDT throughputtraces that indicate complex throughput dynamics. For disk file transfers, we show that throughput can be optimized using a combination of parallel I/O and network threads under direct I/O mode. Our initial throughput measurements of Lustre filesystems mounted over long-haul connections using LNet routers show convex profiles indicative of I/O limits.

  19. Content, Context & Connectivity Persuasive Interplay

    DEFF Research Database (Denmark)

    Sørensen, Christian Grund

    2013-01-01

    -supported research project under EACEA). In the development of this project several categories of content have been implemented in technology enhanced learning tools. These have been designed to support learning in different contexts and eventually the role of the connectivity of these learning objects and tools......The aim of this paper is to discuss the relationship between content, context and connectivity and suggesting a model of Dynamic Interplay. This is done in relation to a specific learning environment concerning cultural mediation, in casu the Kaj Munk Case of the EuroPLOT-project (an EU...... is discussed. Focus is here on The Kaj Munk Study Edition, The Conceptual Pond, Immersive Layers Design, and Generative Learning Objects (GLOs) which are applications affiliated with the Munk case. This paper explores the persuasive potential of the interplay between the different applications for the benefit...

  20. A Building Connecting Separated Communities

    DEFF Research Database (Denmark)

    Axel, Erik

    Producing something for general use involves the designers' anticipation of the use of the object. Personal as well as professional experience is involved in the design anticipations of the process. Using an object means exploring it as a concrete arrangement for our everyday conduct of life....... in no systematic sequence. This, among other things, separates design and use, which is worth investigating in order to understand the problems involved in connecting the design of a house and analyzing the experience of a user. We undertook a preliminary investigation of how a dormitory for visiting students from...... with students from other dormitories, and connect with the Danes from other sections of the building isolating themselves. The janitor was surprised at the supposed function of the washing machines. Since other dormitories at the campus did not provide washing machines, the ones at the house investigated were...

  1. UNBIASED ESTIMATORS OF SPECIFIC CONNECTIVITY

    Directory of Open Access Journals (Sweden)

    Jean-Paul Jernot

    2011-05-01

    Full Text Available This paper deals with the estimation of the specific connectivity of a stationary random set in IRd. It turns out that the "natural" estimator is only asymptotically unbiased. The example of a boolean model of hypercubes illustrates the amplitude of the bias produced when the measurement field is relatively small with respect to the range of the random set. For that reason unbiased estimators are desired. Such an estimator can be found in the literature in the case where the measurement field is a right parallelotope. In this paper, this estimator is extended to apply to measurement fields of various shapes, and to possess a smaller variance. Finally an example from quantitative metallography (specific connectivity of a population of sintered bronze particles is given.

  2. The business case for connectivity

    Science.gov (United States)

    Adams, Dennis; Hirschheim, Rudy

    1991-01-01

    Information systems that provide competitive advantages to organizations can be broadly classified into those that improve the effectiveness of a business function and those that improve the reach of information in the organization. The latter, organizational connectivity systems, can be categorized as intraorganizational and interorganizational systems. Intraorganization systems provide connectivity to function areas within the business, while interorganizational systems support the exchange of business data between independent business units. These system are not confined to a single entity but span organizational boundaries which can be national or international in scope. A series of case studies was undertaken in an effort to better understand the issues and problems associated with providing an increased flow of information within and outside of an organization. Ten issues emerged from this study. In summary, it is necessary for firms to first consider how effective their internal communications systems are before launching projects that tie the organization to external systems.

  3. Ongoing Space Physics - Astrophysics Connections

    OpenAIRE

    Eichler, David

    2005-01-01

    I review several ongoing connections between space physics and astrophysics: a) Measurements of energetic particle spectra have confirmed theoretical prediction of the highest energy to which shocks can accelerate particles, and this has direct bearing on the origin of the highest energy cosmic rays. b) Mass ejection in solar flares may help us understand photon ejection in the giant flares of magnetar outbursts. c) Measurements of electron heat fluxes in the solar wind can help us understand...

  4. Connecting Remote Clusters with ATM

    Energy Technology Data Exchange (ETDEWEB)

    Hu, T.C.; Wyckoff, P.S.

    1998-10-01

    Sandia's entry into utilizing clusters of networked workstations is called Computational Plant or CPlant for short. The design of CPlant uses Ethernet to boot the individual nodes, Myrinet to communicate within a node cluster, and ATM to connect between remote clusters. This SAND document covers the work done to enable the use of ATM on the CPlant nodes in the Fall of 1997.

  5. Regional connectivity in continental ASEAN

    OpenAIRE

    Taguchi, Hiroyuki; Nozaki, Kenji

    2014-01-01

    This chapter examines the issue on Mekong region’s connectivity on quantitative base through the analysis of the gravity trade model and its modified fragmentation model. The main findings are as follows: First, the evolution of international production networks (IPNs) between Thailand and Vietnam as well as the other advanced ASEAN could be identified in terms of their two-way trade integration of machinery parts and components beyond the gravity trade standard. Second, the trade intensity o...

  6. Collective action, clientelism and connectivity

    DEFF Research Database (Denmark)

    Shami, Mahvish

    that the unequal relationship between landlords and peasants does not, in and by itself, block peasant collective action. Rather, it is the interaction between clientelism and isolation that allow patrons to block community based projects. Despite still relying on powerful landlords, peasants in connected villages...... face no such constraints. On the contrary, their patrons assisted them in their collective endeavours, making the hierarchical network an added resource for peasants to rely upon....

  7. Altered Insula Connectivity under MDMA.

    Science.gov (United States)

    Walpola, Ishan C; Nest, Timothy; Roseman, Leor; Erritzoe, David; Feilding, Amanda; Nutt, David J; Carhart-Harris, Robin L

    2017-10-01

    Recent work with noninvasive human brain imaging has started to investigate the effects of 3,4-methylenedioxymethamphetamine (MDMA) on large-scale patterns of brain activity. MDMA, a potent monoamine-releaser with particularly pronounced serotonin- releasing properties, has unique subjective effects that include: marked positive mood, pleasant/unusual bodily sensations and pro-social, empathic feelings. However, the neurobiological basis for these effects is not properly understood, and the present analysis sought to address this knowledge gap. To do this, we administered MDMA-HCl (100 mg p.o.) and, separately, placebo (ascorbic acid) in a randomized, double-blind, repeated-measures design with twenty-five healthy volunteers undergoing fMRI scanning. We then employed a measure of global resting-state functional brain connectivity and follow-up seed-to-voxel analysis to the fMRI data we acquired. Results revealed decreased right insula/salience network functional connectivity under MDMA. Furthermore, these decreases in right insula/salience network connectivity correlated with baseline trait anxiety and acute experiences of altered bodily sensations under MDMA. The present findings highlight insular disintegration (ie, compromised salience network membership) as a neurobiological signature of the MDMA experience, and relate this brain effect to trait anxiety and acutely altered bodily sensations-both of which are known to be associated with insular functioning.

  8. YOUNG ATHLETES' MOTIVATIONAL PROFILES

    Directory of Open Access Journals (Sweden)

    Juan Antonio Moreno Murcia

    2007-06-01

    Full Text Available The aim of this study was to examine the relationship between motivational characteristics and dispositional flow. In order to accomplish this goal, motivational profiles emerging from key constructs within Achievement Goal Theory and Self-Determination Theory were related to the dispositional flow measures. A sample of 413 young athletes (Age range 12 to 16 years completed the PMCSQ-2, POSQ, SMS and DFS measures. Cluster analysis results revealed three profiles: a "self-determined profile" characterised by higher scores on the task-involving climate perception and on the task orientation; a "non-self-determined profile", characterised by higher scores on ego-involving climate perception and ego orientation; and a "low self-determined and low non-self-determined profile" which had the lowest dispositional flow. No meaningful differences were found between the "self-determined profile" and the "non-self-determined profile" in dispositional flow. The "self-determined profile" was more commonly associated with females, athletes practising individual sports and those training more than three days a week. The "non-self-determined profile" was more customary of males and athletes practising team sports as well as those training just two or three days a week

  9. Stationary neoclassical profiles of plasma parameters in stellarators

    International Nuclear Information System (INIS)

    Danilkin, I.S.; Mineev, A.B.

    1991-01-01

    The properties of the neoclassical model of heat and particle transport are considered in connection with calculations of stationary profiles of the plasma parameters in stellarators. The most important feature is the poor agreement with real physical conditions of the boundary, which imposes the necessity of invoking either an additional anomalous transport or a special (although technically possible) consistency between the particle and heat sources in order to obtain a solution in the form of a correct monotonically decreasing profile. In search for monotonic stationary profiles maintained by external sources, it is ascertained that the neoclassical theory does not give rise to the well-known multivalued solutions for the ambipolar electric field

  10. Informatics Solutions for Prosumers connected to Smart Grids

    Directory of Open Access Journals (Sweden)

    Simona Vasilica OPREA

    2015-03-01

    Full Text Available This paper gives a brief overview about electricity consumption optimization based on consumption profiles of electricity prosumers that are connected to smart grids. The main object of this approach is identification of informatics solutions for electricity consumption optimization in order to decrease electricity bill. In this way, larger scale integration of renewable energy sources is allowed therefore entire society will gain benefits. This paper describes the main objectives of such informatics system and stages for its implementation. The system will analyze the specific profile and behavior of each electricity consumer or prosumer, automatically assist him to make right decisions and offer optimal advice for usage of controllable and non-controllable appliances. It will serve, based on big data transfer from electricity consumers or prosumers, as a powerful tool for grid operators that will be able to better plan their resources.

  11. The LncRNA Connectivity Map: Using LncRNA Signatures to Connect Small Molecules, LncRNAs, and Diseases.

    Science.gov (United States)

    Yang, Haixiu; Shang, Desi; Xu, Yanjun; Zhang, Chunlong; Feng, Li; Sun, Zeguo; Shi, Xinrui; Zhang, Yunpeng; Han, Junwei; Su, Fei; Li, Chunquan; Li, Xia

    2017-07-27

    Well characterized the connections among diseases, long non-coding RNAs (lncRNAs) and drugs are important for elucidating the key roles of lncRNAs in biological mechanisms in various biological states. In this study, we constructed a database called LNCmap (LncRNA Connectivity Map), available at http://www.bio-bigdata.com/LNCmap/ , to establish the correlations among diseases, physiological processes, and the action of small molecule therapeutics by attempting to describe all biological states in terms of lncRNA signatures. By reannotating the microarray data from the Connectivity Map database, the LNCmap obtained 237 lncRNA signatures of 5916 instances corresponding to 1262 small molecular drugs. We provided a user-friendly interface for the convenient browsing, retrieval and download of the database, including detailed information and the associations of drugs and corresponding affected lncRNAs. Additionally, we developed two enrichment analysis methods for users to identify candidate drugs for a particular disease by inputting the corresponding lncRNA expression profiles or an associated lncRNA list and then comparing them to the lncRNA signatures in our database. Overall, LNCmap could significantly improve our understanding of the biological roles of lncRNAs and provide a unique resource to reveal the connections among drugs, lncRNAs and diseases.

  12. Polar measurements on profiles

    Energy Technology Data Exchange (ETDEWEB)

    Althaus, D.

    1985-03-01

    Wind tunnel models with a profile depth of t=0.5 m were measured in a laminar wind tunnel by the usual measuring processes. The profile resistance was determined by integration along the width of span. The smooth profiles were examined at Re=0.7/1.0 and 1.5 million. At Re=1.0 million, the position of the changeover points were determined with a stethoscope. Also at this Reynolds number measurements were taken with a trip wire of d=2 mm diameter, directly on the profile nose. The tables contain the co-ordinates of the profiles, the contours, the theoretical speed distributions for 4 different angles of attack, the csub(a)-csub(w) polar measurements and changeover points, and the torque coefficients around the t/4 point. (BR).

  13. Implicit User Interest Profile

    CERN Document Server

    Chan, K

    2002-01-01

    User interest profile presents items that the users are interested in. Typically those items can be listed or grouped. Listing is good but it does not possess interests at different abstraction levels - the higher-level interests are more general, while the lower-level ones are more specific. Furthermore, more general interests, in some sense, correspond to longer-term interests, while more specific interests correspond to shorter-term interests. This hierarchical user interest profile has obvious advantages: specifying user's specific interests and general interests and representing their relationships. Current user interest profile structures mostly do not use implicit method, nor use an appropriate clustering algorithm especially for conceptually hierarchical structures. This research studies building a hierarchical user interest profile (HUIP) and the hierarchical divisive algorithm (HDC). Several users visit hundreds of web pages and each page is recorded in each users profile. These web pages are used t...

  14. Profiles of an Acquisition Generation: Nontraditional Heritage Speakers of Spanish

    Science.gov (United States)

    DeFeo, Dayna Jean

    2018-01-01

    Though definitions vary, the literature on heritage speakers of Spanish identifies two primary attributes: a linguistic and cultural connection to the language. This article profiles four Anglo college students who grew up in bilingual or Spanish-dominant communities in the Southwest who self-identified as Spanish heritage speakers, citing…

  15. The smart/connected city and its implications for connected transportation.

    Science.gov (United States)

    2014-10-14

    This white paper outlines the potential for the emerging connected transportation system to interface with smart/connected cities. Its aim is to lay the foundation for defining steps that the U.S. Department of Transportation (USDOT) Connected Vehicl...

  16. Study of rectenna array connection

    Energy Technology Data Exchange (ETDEWEB)

    Miura, T.; Shinohara, N.; Matsumoto, H. [Kyoto Univ., Uji (Japan). Engineering Research Inst.

    1997-11-01

    A study was conducted in which a new rectenna working at 2.45 GHz microwave was developed for ground-to-ground microwave power transmission. The new rectenna consists of an antenna section and a rectifying section. The new design is simple and therefore more accurate than a micro-strip type patch antenna. The efficiency of conversion of microwave power to direct current depends on the mutual dependence of antenna elements and circuit conditions of rectifying sections. A series of experiments were conducted to analyze the rectenna characteristics and a method for efficiently connecting rectenna arrays was proposed. 3 refs., 2 tabs., 15 figs.

  17. CODAC systems arrangement and connectivity

    Energy Technology Data Exchange (ETDEWEB)

    Gulati, Hitesh Kumar, E-mail: hkgulati@gmail.com; Beltran, David; Kuehn, Ingo; Kotamaki, Miikka; Makijarvi, Petri; Wallander, Anders

    2013-10-15

    Highlights: •The CODAC system is a distributed system and scattered in many buildings connected with cables. Building construction for ITER project is just started so volume reservation for different CODAC component is done based on the content of this paper. •The 2-D and 3-D diagrams have been prepared which are showing the location of different CODAC equipment and their connectivity. •The different requirements regarding raised access (false) floor, power requirements, heat load, installation, maintenance, redundancy, and segregation etc. have been considered. -- Abstract: The CODAC system is responsible for integrating all ITER plant system Instrumentation and Control systems and enabling operation of ITER machine as a single integrated facility. The different ITER plant systems and their Instrumentation and Control systems are distributed in several ITER buildings on the ITER platform. The CODAC systems have to interface with all these distributed plant system I and C systems. CODAC systems will be composed of several physical systems or components like networks, servers, workstations (terminals), large displays, PSH, storage systems etc. Several rooms in different buildings have been defined to house all above equipment. The site-wide CODAC network infrastructure will be based on a dual (redundant) star topology. The two redundant star points will house the core networking switches. These redundant core switches will be installed in different buildings. Cubicles used for network infrastructure are distributed among “hutches,” where a CODAC hutch is a room or area equipped with appropriate heating, ventilation, air conditioning and uninterruptible power which will be directly connected through two star points. The responsibility of CODAC infrastructure ends up to the plant system I and C cubicles so several passive CODAC network panels have identified in all I and C rooms of different plant buildings. This CODAC Network Panel will be the physical

  18. Recreating Intimacy With Connected Consumers

    Directory of Open Access Journals (Sweden)

    Stephen Andrew

    2017-11-01

    Full Text Available In the good old times shop manager knew their customers personally and were able to tailor offerings to their needs and desires. But how can we create meaningful moments for connected consumers in global markets? Yasmeen Ahmad explains how in digital times data fill in. Smart algorithms help generate insights and enable real time action to provide the right product and service to the right customer at the right time. Companies that don’t want to be left behind a digital elite need to remain close to their customers across multiple digital touchpoints. Being capable of reading, interpreting and acting upon consumers` traces is a prerequisite.

  19. Battery impedance spectroscopy using bidirectional grid connected

    Indian Academy of Sciences (India)

    Keywords. Impedance spectroscopy; grid connection; battery converter; state of charge; health monitoring ... The converter is grid connected and controlled to operate at unity power factor. Additional ... Sadhana. Current Issue : Vol. 43, Issue 6.

  20. Connecting Related Rates and Differential Equations

    Science.gov (United States)

    Brandt, Keith

    2012-01-01

    This article points out a simple connection between related rates and differential equations. The connection can be used for in-class examples or homework exercises, and it is accessible to students who are familiar with separation of variables.

  1. National connected vehicle field infrastructure footprint analysis.

    Science.gov (United States)

    2014-06-01

    The fundamental premise of the connected vehicle initiative is that enabling wireless connectivity among vehicles, the infrastructure, and mobile devices will bring about transformative changes in safety, mobility, and the environmental impacts in th...

  2. Connected and autonomous vehicles 2040 vision.

    Science.gov (United States)

    2014-07-01

    The Pennsylvania Department of Transportation (PennDOT) commissioned a one-year project, Connected and Autonomous : Vehicles 2040 Vision, with researchers at Carnegie Mellon University (CMU) to assess the implications of connected and : autonomous ve...

  3. Connectivity editing for quadrilateral meshes

    KAUST Repository

    Peng, Chihan; Zhang, Eugene; Kobayashi, Yoshihiro; Wonka, Peter

    2011-01-01

    We propose new connectivity editing operations for quadrilateral meshes with the unique ability to explicitly control the location, orientation, type, and number of the irregular vertices (valence not equal to four) in the mesh while preserving sharp edges. We provide theoretical analysis on what editing operations are possible and impossible and introduce three fundamental operations to move and re-orient a pair of irregular vertices. We argue that our editing operations are fundamental, because they only change the quad mesh in the smallest possible region and involve the fewest irregular vertices (i.e., two). The irregular vertex movement operations are supplemented by operations for the splitting, merging, canceling, and aligning of irregular vertices. We explain how the proposed highlevel operations are realized through graph-level editing operations such as quad collapses, edge flips, and edge splits. The utility of these mesh editing operations are demonstrated by improving the connectivity of quad meshes generated from state-of-art quadrangulation techniques. © 2011 ACM.

  4. Connectivity editing for quadrilateral meshes

    KAUST Repository

    Peng, Chihan

    2011-12-12

    We propose new connectivity editing operations for quadrilateral meshes with the unique ability to explicitly control the location, orientation, type, and number of the irregular vertices (valence not equal to four) in the mesh while preserving sharp edges. We provide theoretical analysis on what editing operations are possible and impossible and introduce three fundamental operations to move and re-orient a pair of irregular vertices. We argue that our editing operations are fundamental, because they only change the quad mesh in the smallest possible region and involve the fewest irregular vertices (i.e., two). The irregular vertex movement operations are supplemented by operations for the splitting, merging, canceling, and aligning of irregular vertices. We explain how the proposed highlevel operations are realized through graph-level editing operations such as quad collapses, edge flips, and edge splits. The utility of these mesh editing operations are demonstrated by improving the connectivity of quad meshes generated from state-of-art quadrangulation techniques. © 2011 ACM.

  5. Astrophysicists' conversational connections on Twitter.

    Directory of Open Access Journals (Sweden)

    Kim Holmberg

    Full Text Available Because Twitter and other social media are increasingly used for analyses based on altmetrics, this research sought to understand what contexts, affordance use, and social activities influence the tweeting behavior of astrophysicists. Thus, the presented study has been guided by three research questions that consider the influence of astrophysicists' activities (i.e., publishing and tweeting frequency and of their tweet construction and affordance use (i.e. use of hashtags, language, and emotions on the conversational connections they have on Twitter. We found that astrophysicists communicate with a variety of user types (e.g. colleagues, science communicators, other researchers, and educators and that in the ego networks of the astrophysicists clear groups consisting of users with different professional roles can be distinguished. Interestingly, the analysis of noun phrases and hashtags showed that when the astrophysicists address the different groups of very different professional composition they use very similar terminology, but that they do not talk to each other (i.e. mentioning other user names in tweets. The results also showed that in those areas of the ego networks that tweeted more the sentiment of the tweets tended to be closer to neutral, connecting frequent tweeting with information sharing activities rather than conversations or expressing opinions.

  6. Embedded adhesive connection for laminated glass plates

    DEFF Research Database (Denmark)

    Hansen, Jens Zangenberg; Poulsen, S.H.; Bagger, A.

    2012-01-01

    The structural behavior of a new connection design, the embedded adhesive connection, used for laminated glass plates is investigated. The connection consists of an aluminum plate encapsulated in-between two adjacent triple layered laminated glass plates. Fastening between glass and aluminum...... usage in a design situation. The embedded connection shows promising potential as a future fastening system for load-carrying laminated glass plates....

  7. Accelerating Information Retrieval from Profile Hidden Markov Model Databases.

    Science.gov (United States)

    Tamimi, Ahmad; Ashhab, Yaqoub; Tamimi, Hashem

    2016-01-01

    Profile Hidden Markov Model (Profile-HMM) is an efficient statistical approach to represent protein families. Currently, several databases maintain valuable protein sequence information as profile-HMMs. There is an increasing interest to improve the efficiency of searching Profile-HMM databases to detect sequence-profile or profile-profile homology. However, most efforts to enhance searching efficiency have been focusing on improving the alignment algorithms. Although the performance of these algorithms is fairly acceptable, the growing size of these databases, as well as the increasing demand for using batch query searching approach, are strong motivations that call for further enhancement of information retrieval from profile-HMM databases. This work presents a heuristic method to accelerate the current profile-HMM homology searching approaches. The method works by cluster-based remodeling of the database to reduce the search space, rather than focusing on the alignment algorithms. Using different clustering techniques, 4284 TIGRFAMs profiles were clustered based on their similarities. A representative for each cluster was assigned. To enhance sensitivity, we proposed an extended step that allows overlapping among clusters. A validation benchmark of 6000 randomly selected protein sequences was used to query the clustered profiles. To evaluate the efficiency of our approach, speed and recall values were measured and compared with the sequential search approach. Using hierarchical, k-means, and connected component clustering techniques followed by the extended overlapping step, we obtained an average reduction in time of 41%, and an average recall of 96%. Our results demonstrate that representation of profile-HMMs using a clustering-based approach can significantly accelerate data retrieval from profile-HMM databases.

  8. Accelerating Information Retrieval from Profile Hidden Markov Model Databases.

    Directory of Open Access Journals (Sweden)

    Ahmad Tamimi

    Full Text Available Profile Hidden Markov Model (Profile-HMM is an efficient statistical approach to represent protein families. Currently, several databases maintain valuable protein sequence information as profile-HMMs. There is an increasing interest to improve the efficiency of searching Profile-HMM databases to detect sequence-profile or profile-profile homology. However, most efforts to enhance searching efficiency have been focusing on improving the alignment algorithms. Although the performance of these algorithms is fairly acceptable, the growing size of these databases, as well as the increasing demand for using batch query searching approach, are strong motivations that call for further enhancement of information retrieval from profile-HMM databases. This work presents a heuristic method to accelerate the current profile-HMM homology searching approaches. The method works by cluster-based remodeling of the database to reduce the search space, rather than focusing on the alignment algorithms. Using different clustering techniques, 4284 TIGRFAMs profiles were clustered based on their similarities. A representative for each cluster was assigned. To enhance sensitivity, we proposed an extended step that allows overlapping among clusters. A validation benchmark of 6000 randomly selected protein sequences was used to query the clustered profiles. To evaluate the efficiency of our approach, speed and recall values were measured and compared with the sequential search approach. Using hierarchical, k-means, and connected component clustering techniques followed by the extended overlapping step, we obtained an average reduction in time of 41%, and an average recall of 96%. Our results demonstrate that representation of profile-HMMs using a clustering-based approach can significantly accelerate data retrieval from profile-HMM databases.

  9. Medical professionalism: an experimental look at physicians’ Facebook profiles

    Directory of Open Access Journals (Sweden)

    Joseph W. Clyde

    2014-06-01

    Full Text Available Background: Use of social networking services (SNS is on the rise. While many users sign in for personal purposes, it is not uncommon for professionals to connect over SNSs with clients, students, and patients. Methods: The present study used an experimental approach to examine how medical doctors’ SNS profiles impacted potential patients’ impressions of professionalism. Participants (N=250 students were randomly assigned to view one of six Facebook profiles. Profiles were populated with 1 solely professional material, 2 personal material that was strictly healthy, or 3 personal material that included unhealthy behavior. Profiles portrayed a male or female physician resulting in a total of six experimental conditions. Medical professionalism was measured with the First Impressions of Medical Professionalism (FIMP scale, specifically developed for this study. Results: There was a large and statistically significant main effect for profile type, F(2, 250=54.77, p<0.001, ηp2=0.31. Post hoc tests indicated that personal profiles that contained healthy behavior were rated as most professional followed by profiles with strictly professional content. Personal unhealthy profiles were rated as least professional. Additionally, female profiles consistently received higher professionalism ratings across all three profile types [F(1, 250=5.04, p=0.026, ηp2=0.02]. Conclusion: Our results suggest that a physician's SNS profile affects a patient's perception of that physician's medical professionalism. A personal, healthy profile may augment a patient's perception of that physician's character virtues if the profile content upholds the decorum of the medical field.

  10. Intermodal connectivity in Europe, an empirical exploration

    NARCIS (Netherlands)

    de Langen, P.W.; Lases Figueroa, D.M.; van Donselaar, K.H.; Bozuwa, J.

    2017-01-01

    In this paper we analyse the intermodal connectivity in Europe. The empirical analysis is to our knowledge the first empirical analysis of intermodal connections, and is based on a comprehensive database of intermodal connections in Europe. The paper focuses on rail and barge services, as they are

  11. Airport industry connectivity report: 2004-2014

    NARCIS (Netherlands)

    Burghouwt, G.; Lieshout, R.

    2014-01-01

    Airport connectivity is an increasingly discussed topic in European policy circles. With good reason. Connectivity is closely connected with productivity, economic growth and international trade. And with the centre of global economic activity shifting eastward, it is essential that Europe remains

  12. MedlinePlus Connect: Web Service

    Science.gov (United States)

    ... MedlinePlus Connect → Web Service URL of this page: https://medlineplus.gov/connect/service.html MedlinePlus Connect: Web ... will change.) Old URLs New URLs Web Application https://apps.nlm.nih.gov/medlineplus/services/mpconnect.cfm? ...

  13. MedlinePlus Connect: Web Application

    Science.gov (United States)

    ... MedlinePlus Connect → Web Application URL of this page: https://medlineplus.gov/connect/application.html MedlinePlus Connect: Web ... will change.) Old URLs New URLs Web Application https://apps.nlm.nih.gov/medlineplus/services/mpconnect.cfm? ...

  14. MedlinePlus Connect: Technical Information

    Science.gov (United States)

    ... MedlinePlus Connect → Technical Information URL of this page: https://medlineplus.gov/connect/technical.html MedlinePlus Connect: Technical ... will change.) Old URLs New URLs Web Application https://apps.nlm.nih.gov/medlineplus/services/mpconnect.cfm? ...

  15. MedlinePlus Connect: Email List

    Science.gov (United States)

    ... MedlinePlus Connect → Email List URL of this page: https://medlineplus.gov/connect/emaillist.html MedlinePlus Connect: Email ... will change.) Old URLs New URLs Web Application https://apps.nlm.nih.gov/medlineplus/services/mpconnect.cfm? ...

  16. A predictable Java profile

    DEFF Research Database (Denmark)

    Bøgholm, Thomas; Hansen, Rene Rydhof; Ravn, Anders Peter

    2009-01-01

    A Java profile suitable for development of high integrity embedded systems is presented. It is based on event handlers which are grouped in missions and equipped with respectively private handler memory and shared mission memory. This is a result of our previous work on developing a Java profile......, and is directly inspired by interactions with the Open Group on their on-going work on a safety critical Java profile (JSR-302). The main contribution is an arrangement of the class hierarchy such that the proposal is a generalization of Real-Time Specification for Java (RTSJ). A further contribution...

  17. Profiling the Mobile Customer

    DEFF Research Database (Denmark)

    Jessen, Pernille Wegener; King, Nancy J.

    2010-01-01

    of significant concerns about privacy and data protection. This second article in a two part series on "Profiling the Mobile Customer" explores how to best protect consumers' privacy and personal data through available mechanisms that include industry self-regulation, privacy-enhancing technologies...... discusses the current limitations of using technology to protect consumers from privacy abuses related to profiling. Concluding that industry self-regulation and available privacy-enhancing technologies will not be adequate to close important privacy gaps related to consumer profiling without legislative...

  18. Violence and Personality in Forensic Patients: Is There a Forensic Patient-Specific Personality Profile?

    Science.gov (United States)

    Stupperich, Alexandra; Ihm, Helga; Strack, Micha

    2009-01-01

    Concerning the discussion about the connection of personality traits, personality disorders, and mental illness, this study focused on the personality profiles of male forensic patients, prison inmates, and young men without criminal reports. The main topic centered on group-specific personality profiles and identifying personality facets…

  19. Lidar sprectroscopy instrument (LISSI: An infrastructure facility for chemical aerosol profiling at the University of Hertfordshire

    Directory of Open Access Journals (Sweden)

    Tesche Matthias

    2018-01-01

    The new facility will open new avenues for chemical profiling of aerosol pollution from measurements of Raman scattering by selected chemical compounds, provide data that allow to close the gap between optical and microphysical aerosol profiling with lidar and enables connecting lidar measurements to parameters used in atmospheric modelling.

  20. Water level sensor and temperature profile detector

    International Nuclear Information System (INIS)

    Tokarz, R.D.

    1983-01-01

    A temperature profile detector comprising a surrounding length of metal tubing and an interior electrical conductor both constructed of high temperature high electrical resistance materials. A plurality of gas-filled expandable bellows made of electrically conductive material is electrically connected to the interior electrical conductor and positioned within the length of metal tubing. The bellows are sealed and contain a predetermined volume of a gas designed to effect movement of the bellows from an open circuit condition to a closed circuit condition in response to monitored temperature changes sensed by each bellows

  1. Water level sensor and temperature profile detector

    Science.gov (United States)

    Tokarz, Richard D.

    1983-01-01

    A temperature profile detector comprising a surrounding length of metal tubing and an interior electrical conductor both constructed of high temperature high electrical resistance materials. A plurality of gas-filled expandable bellows made of electrically conductive material is electrically connected to the interior electrical conductor and positioned within the length of metal tubing. The bellows are sealed and contain a predetermined volume of a gas designed to effect movement of the bellows from an open circuit condition to a closed circuit condition in response to monitored temperature changes sensed by each bellows.

  2. Connecting multimodality in human communication.

    Science.gov (United States)

    Regenbogen, Christina; Habel, Ute; Kellermann, Thilo

    2013-01-01

    A successful reciprocal evaluation of social signals serves as a prerequisite for social coherence and empathy. In a previous fMRI study we studied naturalistic communication situations by presenting video clips to our participants and recording their behavioral responses regarding empathy and its components. In two conditions, all three channels transported congruent emotional or neutral information, respectively. Three conditions selectively presented two emotional channels and one neutral channel and were thus bimodally emotional. We reported channel-specific emotional contributions in modality-related areas, elicited by dynamic video clips with varying combinations of emotionality in facial expressions, prosody, and speech content. However, to better understand the underlying mechanisms accompanying a naturalistically displayed human social interaction in some key regions that presumably serve as specific processing hubs for facial expressions, prosody, and speech content, we pursued a reanalysis of the data. Here, we focused on two different descriptions of temporal characteristics within these three modality-related regions [right fusiform gyrus (FFG), left auditory cortex (AC), left angular gyrus (AG) and left dorsomedial prefrontal cortex (dmPFC)]. By means of a finite impulse response (FIR) analysis within each of the three regions we examined the post-stimulus time-courses as a description of the temporal characteristics of the BOLD response during the video clips. Second, effective connectivity between these areas and the left dmPFC was analyzed using dynamic causal modeling (DCM) in order to describe condition-related modulatory influences on the coupling between these regions. The FIR analysis showed initially diminished activation in bimodally emotional conditions but stronger activation than that observed in neutral videos toward the end of the stimuli, possibly by bottom-up processes in order to compensate for a lack of emotional information. The

  3. Wind Profiling Radar

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Clutter present in radar return signals as used for wind profiling is substantially removed by carrying out a Daubechies wavelet transformation on a time series of...

  4. Fishing fleet profiling methodology

    National Research Council Canada - National Science Library

    Ferraris, Jocelyne

    2002-01-01

    A fishing fleet profile aims tho assist in understanding the complexity and structure of fisheries from a technical and socio-economic point of view, or from the point of view of fishing strategies...

  5. Beach Profile Locations

    Data.gov (United States)

    California Natural Resource Agency — Beaches are commonly characterized by cross-shore surveys. The resulting profiles represent the elevation of the beach surface and nearshore seabed from the back of...

  6. Secretaries: A Profile.

    Science.gov (United States)

    Fusselman, Kay

    1987-01-01

    Consists of the results of a profile survey completed by more than 12,000 members of Professional Secretaries International. Information is included on secretarial titles, salaries, employer types, and secretaries' personal characteristics. (CH)

  7. Prescription Drug Profiles PUF

    Data.gov (United States)

    U.S. Department of Health & Human Services — This release contains the Prescription Drug Profiles Public Use Files (PUFs) drawn from Medicare prescription drug claims for the year of the date on which the...

  8. Fishing Community Profiles

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — To enable fisheries managers to comply with National Standard 8 (NS8), NMFS social scientists around the nation are preparing fishing community profiles that present...

  9. Behavior of concentrically loaded CFT braces connections

    Directory of Open Access Journals (Sweden)

    Maha M. Hassan

    2014-03-01

    Full Text Available Concrete filled tubes (CFTs composite columns have many economical and esthetic advantages, but the behavior of their connections is complicated. Through this study, it is aimed to investigate the performance and behavior of different connection configurations between concrete filled steel tube columns and bracing diagonals through an experimental program. The study included 12 connection subassemblies consisting of a fixed length steel tube and gusset plate connected to the tube end with different details tested under half cyclic loading. A notable effect was observed on the behavior of the connections due to its detailing changes with respect to capacity, failure mode, ductility, and stress distribution.

  10. Are PES connection costs too high?

    International Nuclear Information System (INIS)

    Scott, N.

    1998-01-01

    Windfarm developers often have good reason to question the costs they are quoted by their local distribution company for connection to the system, and these costs can now be challenged under the 'Competition in Connection' initiative. Econnect Ltd specialise in electrical connections for renewable generation throughout the UK and Europe, and have worked on many projects where alternative connections have been designed at more competitive prices. This paper provides some examples which illustrate the importance of acquiring a thorough understanding of all power system issues and PES concerns if the most cost-effective connection is to be realised. (Author)

  11. Twistor connection and the Palatini method

    International Nuclear Information System (INIS)

    Merkulov, S.A.

    1988-01-01

    For the Yang-Mills Lagrangian of the twistor connection, an analog of the Palatini variational method is considered, in which the variations of the twistor connection A m and metric g ab are taken to be independent. It is shown that varying the Lagrangian with respect to the connection establishes a relation between A m and g ab (i.e., defines a standard twistor connection, postulated earlier), while varying with respect to the metric with a subsequent substitution of explicit expressions of the standard twistor connection leads to the Bach vacuum equations, describing the dynamics of conformal gravity

  12. Unity connecting module in SSPF

    Science.gov (United States)

    1998-01-01

    In the Space Station Processing Facility, the Unity connecting module, part of the International Space Station, is shown with Pressurized Mating Adapters 1 (left) and 2 (right) attached. Unity is scheduled to undergo testing of the common berthing mechanism to which other space station elements will dock. Unity is the primary payload on mission STS-88, targeted to launch Dec. 3, 1998. Other testing includes the Pad Demonstration Test to verify the compatibility of the module with the Space Shuttle as well as the ability of the astronauts to send and receive commands to Unity from the flight deck of the orbiter. Unity is expected to be ready for installation into the payload canister on Oct. 25, and transported to Launch Pad 39-A on Oct. 27. The Unity will be mated to the Russian-built Zarya control module which should already be in orbit at that time.

  13. Sprays and Cartan projective connections

    Science.gov (United States)

    Saunders, D. J.

    2004-10-01

    Around 80 years ago, several authors (for instance H. Weyl, T.Y. Thomas, J. Douglas and J.H.C. Whitehead) studied the projective geometry of paths, using the methods of tensor calculus. The principal object of study was a spray, namely a homogeneous second-order differential equation, or more generally a projective equivalence class of sprays. At around the same time, E. Cartan studied the same topic from a different point of view, by imagining a projective space attached to a manifold, or, more generally, attached to a `manifold of elements'; the infinitesimal `glue' may be interpreted in modern language as a Cartan projective connection on a principal bundle. This paper describes the geometrical relationship between these two points of view.

  14. Ultraviolet injury of connective tissue

    International Nuclear Information System (INIS)

    Sengupta, K.P.; Sanyal, Sabitri; Biswas, S.K.; Pal, N.C.

    1975-01-01

    Changes induced by UV irradiation of rat skin could be divided morphologically into prenecrotic, necrotic and regenerating phases. During prenecrotic and necrotic phases, decrease in water content, collagenous protein, citrate buffer soluble fraction, elastin and total lipid and its fractions, and increase in noncollagenous protein nitrogen and fucoglycoprotein were observed. Increase in serum and urinary hydroxyproline and hexosamine, and serum sialic acid and fucose revealed the complicated nature of intrinsic changes occurring systemically. The study revealed that the ground substance was more easily affected while collagen, elastin and fat appeared to be more resistant to injury. This could be due to superficial action of radiation of short duration (30 min) on the dermal connective tissue. (author)

  15. Method for hermetic electrical connections

    Science.gov (United States)

    Monroe, Saundra L [Tijeras, NM; Glass, S Jill [Albuquerque, NM; Stone, Ronnie G [Albuquerque, NM; Bond, Jamey T [Albuquerque, NM; Susan, Donald F [Albuquerque, NM

    2011-12-27

    A method of providing a hermetic, electrical connection between two electrical components by mating at least one metal pin in a glass-ceramic to metal seal connector to two electrical components, wherein the glass-ceramic to metal seal connector incorporates at least one metal pin encased (sealed) in a glass-ceramic material inside of a metal housing, with the glass-ceramic material made from 65-80% SiO.sub.2, 8-16% Li.sub.2O, 2-8% Al.sub.2O.sub.3, 1-5% P.sub.2O.sub.5, 1-8% K.sub.2O, 0.5-7% B.sub.2O.sub.3, and 0-5% ZnO. The connector retains hermeticity at temperatures as high as 700.degree. C. and pressures as high as 500 psi.

  16. Connecting cognition and consumer choice.

    Science.gov (United States)

    Bartels, Daniel M; Johnson, Eric J

    2015-02-01

    We describe what can be gained from connecting cognition and consumer choice by discussing two contexts ripe for interaction between the two fields. The first-context effects on choice-has already been addressed by cognitive science yielding insights about cognitive process but there is promise for more interaction. The second is learning and representation in choice where relevant theories in cognitive science could be informed by consumer choice, and in return, could pose and answer new questions. We conclude by discussing how these two fields of research stand to benefit from more interaction, citing examples of how interfaces of cognitive science with other fields have been illuminating for theories of cognition. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Connected health and multiple sclerosis.

    Science.gov (United States)

    Cohen, M

    2018-04-18

    There is as yet no consensual definition of "connected health". In general, the term refers to the growing use of technology and, in particular, mobile technology in medicine. Over the past 10 years, there have been an increasing number of published reports on the wide-ranging and heterogeneous fields involving the application of technology in medicine, ranging from telemedicine to tools to improve patients' evaluation and monitoring by physicians, as well as a multitude of patient-centered applications. They also represent promising tools in the field of clinical research. This report is a review of the importance of using this technology in the management of multiple sclerosis patients. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

  18. Global oil company profiles

    International Nuclear Information System (INIS)

    1997-01-01

    Global Oil Company Profiles provides a comprehensive review of 50 of the top oil companies in the world. Each chapter is devoted to an individual company, providing an invaluable insight into the organisation, its structure and operations. Using the most recent data available, the report offers an up-to-date analysis of performance and future direction, as well as a unique benchmarking system for each company profiled. (author)

  19. Laquinimod Safety Profile

    DEFF Research Database (Denmark)

    Sørensen, Per Soelberg; Comi, Giancarlo; Vollmer, Timothy L

    2017-01-01

    the safety profile of laquinimod versus placebo. Adverse events (AEs), laboratory value changes, and potential risks identified in preclinical studies were evaluated in participants in ALLEGRO and BRAVO treated with at least one dose of laquinimod or matching placebo (1:1 random assignment). RESULTS...... laquinimod studies demonstrate a safety profile comprising benign or manageable AEs and asymptomatic laboratory findings with a clear temporal pattern. Potential risks noted in preclinical studies were not observed....

  20. Household electricity demand profiles

    DEFF Research Database (Denmark)

    Marszal, Anna Joanna; Heiselberg, Per Kvols; Larsen, Olena Kalyanova

    2016-01-01

    Highlights •A 1-min resolution household electricity load model is presented. •Model adapts a bottom-up approach with single appliance as the main building block. •Load profiles are used to analyse the flexibility potential of household appliances. •Load profiles can be applied in other domains, .......g. building energy simulations. •The demand level of houses with different number of occupants is well captured....

  1. Country nuclear power profiles

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The preparation of Country Nuclear Power Profiles was initiated within the framework of the IAEA`s programme for nuclear power plant performance assessment and feedback. It responded to a need for a database and a technical document containing a description of the energy and economic situation and the primary organizations involved in nuclear power in IAEA Member States. The task was included in the IAEA`s programmes for 1993/1994 and 1995/1996. In March 1993, the IAEA organized a Technical Committee meeting to discuss the establishment of country data ``profiles``, to define the information to be included in the profiles and to review the information already available in the IAEA. Two expert meetings were convened in November 1994 to provide guidance to the IAEA on the establishment of the country nuclear profiles, on the structure and content of the profiles, and on the preparation of the publication and the electronic database. In June 1995, an Advisory Group meeting provided the IAEA with comprehensive guidance on the establishment and dissemination of an information package on industrial and organizational aspects of nuclear power to be included in the profiles. The group of experts recommended that the profiles focus on the overall economic, energy and electricity situation in the country and on its nuclear power industrial structure and organizational framework. In its first release, the compilation would cover all countries with operating power plants by the end of 1995. It was also recommended to further promote information exchange on the lessons learned from the countries engaged in nuclear programmes. For the preparation of this publication, the IAEA received contributions from the 29 countries operating nuclear power plants and Italy. A database has been implemented and the profiles are supporting programmatic needs within the IAEA; it is expected that the database will be publicly accessible in the future. Refs, figs, tabs.

  2. Country nuclear power profiles

    International Nuclear Information System (INIS)

    1998-03-01

    The preparation of Country Nuclear Power Profiles was initiated within the framework of the IAEA's programme for nuclear power plant performance assessment and feedback. It responded to a need for a database and a technical document containing a description of the energy and economic situation and the primary organizations involved in nuclear power in IAEA Member States. The task was included in the IAEA's programmes for 1993/1994 and 1995/1996. In March 1993, the IAEA organized a Technical Committee meeting to discuss the establishment of country data ''profiles'', to define the information to be included in the profiles and to review the information already available in the IAEA. Two expert meetings were convened in November 1994 to provide guidance to the IAEA on the establishment of the country nuclear profiles, on the structure and content of the profiles, and on the preparation of the publication and the electronic database. In June 1995, an Advisory Group meeting provided the IAEA with comprehensive guidance on the establishment and dissemination of an information package on industrial and organizational aspects of nuclear power to be included in the profiles. The group of experts recommended that the profiles focus on the overall economic, energy and electricity situation in the country and on its nuclear power industrial structure and organizational framework. In its first release, the compilation would cover all countries with operating power plants by the end of 1995. It was also recommended to further promote information exchange on the lessons learned from the countries engaged in nuclear programmes. For the preparation of this publication, the IAEA received contributions from the 29 countries operating nuclear power plants and Italy. A database has been implemented and the profiles are supporting programmatic needs within the IAEA; it is expected that the database will be publicly accessible in the future

  3. Model Predictive Control for Connected Hybrid Electric Vehicles

    Directory of Open Access Journals (Sweden)

    Kaijiang Yu

    2015-01-01

    Full Text Available This paper presents a new model predictive control system for connected hybrid electric vehicles to improve fuel economy. The new features of this study are as follows. First, the battery charge and discharge profile and the driving velocity profile are simultaneously optimized. One is energy management for HEV for Pbatt; the other is for the energy consumption minimizing problem of acc control of two vehicles. Second, a system for connected hybrid electric vehicles has been developed considering varying drag coefficients and the road gradients. Third, the fuel model of a typical hybrid electric vehicle is developed using the maps of the engine efficiency characteristics. Fourth, simulations and analysis (under different parameters, i.e., road conditions, vehicle state of charge, etc. are conducted to verify the effectiveness of the method to achieve higher fuel efficiency. The model predictive control problem is solved using numerical computation method: continuation and generalized minimum residual method. Computer simulation results reveal improvements in fuel economy using the proposed control method.

  4. BWR AXIAL PROFILE

    International Nuclear Information System (INIS)

    Huffer, J.

    2004-01-01

    The purpose of this calculation is to develop axial profiles for estimating the axial variation in burnup of a boiling water reactor (BWR) assembly spent nuclear fuel (SNF) given the average burnup of an assembly. A discharged fuel assembly typically exhibits higher burnup in the center and lower burnup at the ends of the assembly. Criticality safety analyses taking credit for SNF burnup must account for axially varying burnup relative to calculations based on uniformly distributed assembly average burnup due to the under-burned tips. Thus, accounting for axially varying burnup in criticality analyses is also referred to as accounting for the ''end effect'' reactivity. The magnitude of the reactivity change due to ''end effect'' is dependent on the initial assembly enrichment, the assembly average burnup, and the particular axial profile characterizing the burnup distribution. The set of bounding axial profiles should incorporate multiple BWR core designs and provide statistical confidence (95 percent confidence that 95 percent of the population is bound by the profile) that end nodes are conservatively represented. The profiles should also conserve the overall burnup of the fuel assembly. More background on BWR axial profiles is provided in Attachment I

  5. Accelerated Profile HMM Searches.

    Directory of Open Access Journals (Sweden)

    Sean R Eddy

    2011-10-01

    Full Text Available Profile hidden Markov models (profile HMMs and probabilistic inference methods have made important contributions to the theory of sequence database homology search. However, practical use of profile HMM methods has been hindered by the computational expense of existing software implementations. Here I describe an acceleration heuristic for profile HMMs, the "multiple segment Viterbi" (MSV algorithm. The MSV algorithm computes an optimal sum of multiple ungapped local alignment segments using a striped vector-parallel approach previously described for fast Smith/Waterman alignment. MSV scores follow the same statistical distribution as gapped optimal local alignment scores, allowing rapid evaluation of significance of an MSV score and thus facilitating its use as a heuristic filter. I also describe a 20-fold acceleration of the standard profile HMM Forward/Backward algorithms using a method I call "sparse rescaling". These methods are assembled in a pipeline in which high-scoring MSV hits are passed on for reanalysis with the full HMM Forward/Backward algorithm. This accelerated pipeline is implemented in the freely available HMMER3 software package. Performance benchmarks show that the use of the heuristic MSV filter sacrifices negligible sensitivity compared to unaccelerated profile HMM searches. HMMER3 is substantially more sensitive and 100- to 1000-fold faster than HMMER2. HMMER3 is now about as fast as BLAST for protein searches.

  6. Hematopoietic stem cell origin of connective tissues.

    Science.gov (United States)

    Ogawa, Makio; Larue, Amanda C; Watson, Patricia M; Watson, Dennis K

    2010-07-01

    Connective tissue consists of "connective tissue proper," which is further divided into loose and dense (fibrous) connective tissues and "specialized connective tissues." Specialized connective tissues consist of blood, adipose tissue, cartilage, and bone. In both loose and dense connective tissues, the principal cellular element is fibroblasts. It has been generally believed that all cellular elements of connective tissue, including fibroblasts, adipocytes, chondrocytes, and bone cells, are generated solely by mesenchymal stem cells. Recently, a number of studies, including those from our laboratory based on transplantation of single hematopoietic stem cells, strongly suggested a hematopoietic stem cell origin of these adult mesenchymal tissues. This review summarizes the experimental evidence for this new paradigm and discusses its translational implications. Copyright 2010 ISEH - Society for Hematology and Stem Cells. All rights reserved.

  7. Radiotherapy in patients with connective tissue diseases.

    Science.gov (United States)

    Giaj-Levra, Niccolò; Sciascia, Savino; Fiorentino, Alba; Fersino, Sergio; Mazzola, Rosario; Ricchetti, Francesco; Roccatello, Dario; Alongi, Filippo

    2016-03-01

    The decision to offer radiotherapy in patients with connective tissue diseases continues to be challenging. Radiotherapy might trigger the onset of connective tissue diseases by increasing the expression of self-antigens, diminishing regulatory T-cell activity, and activating effectors of innate immunity (dendritic cells) through Toll-like receptor-dependent mechanisms, all of which could potentially lead to breaks of immune tolerance. This potential risk has raised some debate among radiation oncologists about whether patients with connective tissue diseases can tolerate radiation as well as people without connective tissue diseases. Because the number of patients with cancer and connective tissue diseases needing radiotherapy will probably increase due to improvements in medical treatment and longer life expectancy, the issue of interactions between radiotherapy and connective tissue diseases needs to be clearer. In this Review, we discuss available data and evidence for patients with connective tissue diseases treated with radiotherapy. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Random geometric graphs with general connection functions

    Science.gov (United States)

    Dettmann, Carl P.; Georgiou, Orestis

    2016-03-01

    In the original (1961) Gilbert model of random geometric graphs, nodes are placed according to a Poisson point process, and links formed between those within a fixed range. Motivated by wireless ad hoc networks "soft" or "probabilistic" connection models have recently been introduced, involving a "connection function" H (r ) that gives the probability that two nodes at distance r are linked (directly connect). In many applications (not only wireless networks), it is desirable that the graph is connected; that is, every node is linked to every other node in a multihop fashion. Here the connection probability of a dense network in a convex domain in two or three dimensions is expressed in terms of contributions from boundary components for a very general class of connection functions. It turns out that only a few quantities such as moments of the connection function appear. Good agreement is found with special cases from previous studies and with numerical simulations.

  9. Online Professional Profiles: Health Care and Library Researchers Show Off Their Work.

    Science.gov (United States)

    Brigham, Tara J

    2016-01-01

    In an increasingly digital world, online profiles can help health care and library professionals showcase their research and scholarly work. By sharing information about their investigations, studies, and projects, health care and library researchers can elevate their personal brand and connect with like-minded individuals. This column explores different types of online professional profiles and addresses some of the concerns that come with using them. A list of online professional profile and platform examples is also provided.

  10. Connecting Leadership and Learning: Do Versatile Learners make Connective Leaders?

    Directory of Open Access Journals (Sweden)

    Jill L. Robinson

    2016-03-01

    Full Text Available Abstract Recent failures in leadership, suggest that creating better-quality leadership development programs is critical. In moving from theory to practice, this paper examined the relationship between learning style and leadership style which may enable us to move away from one-size-fits-all leadership development programs. Utilizing Kolb’s Experiential Learning Model and Connective Leadership theory, approximately 3600 college students were analyzed to discover whether versatility in learning styles translates into versatility in leadership styles. One group of versatile learners reported using a wider range of leadership styles suggesting that learning flexibility may transfer to leadership flexibility. Surprisingly, learners of all types reported utilizing Power and Intrinsic styles of leadership above all others. Implications for leadership development include considering individual differences when crafting leadership programs, matching learning styles to leader training, and the need to move beyond one set of leadership behaviors to increase flexibility in dealing with complex situations. Using a large sample rarely seen in management studies, this paper makes key contributions to the literature. 

  11. The effects of psychosis risk variants on brain connectivity: A Meta-analysis

    Directory of Open Access Journals (Sweden)

    Omar eMothersill

    2012-03-01

    Full Text Available In light of observed changes in connectivity in schizophrenia and the highly heritable nature of the disease, neural connectivity may serve as an important intermediate phenotype for schizophrenia. However, how individual variants confer altered connectivity and which measure of brain connectivity is more proximal to the underlying genetic architecture (i.e. functional or structural has not been well delineated. In this review we consider these issues and the relative sensitivity of imaging methodologies to schizophrenia-related changes in connectivity.We searched PubMed for studies considering schizophrenia risk genes AND functional or structural connectivity. Where data was available, summary statistics were used to determine an estimate of effect size (i.e. Cohen’s d. A random-effects meta-analysis was used to consider (1 the largest effect and (2 all significant effects between functional and structural studies. Schizophrenia risk variants involved in neurotransmission, neurodevelopment and myelin function were found to be associated with altered neural connectivity. On average, schizophrenia risk genes had a large effect on functional (mean d=0.76 and structural connectivity (mean d=1.04. The examination of the largest effect size indicated that the outcomes of functional and structural studies were comparable (Q=2.17, p>0.05. Conversely, consideration of effect size estimates for all significant effects suggest that reported effect sizes in structural connectivity studies were more variable than in functional connectivity studies, and that there was a significant lack of homogeneity across the modalities (Q=6.928, p=0.008.Given the more variable profile of effect sizes associated with structural connectivity, these data may suggest that structural imaging methods are more sensitive to a wider range of effects, as opposed to functional studies which may only be able to determine large effects. These conclusions are limited by

  12. Precision enhancement of pavement roughness localization with connected vehicles

    International Nuclear Information System (INIS)

    Bridgelall, R; Huang, Y; Zhang, Z; Deng, F

    2016-01-01

    Transportation agencies rely on the accurate localization and reporting of roadway anomalies that could pose serious hazards to the traveling public. However, the cost and technical limitations of present methods prevent their scaling to all roadways. Connected vehicles with on-board accelerometers and conventional geospatial position receivers offer an attractive alternative because of their potential to monitor all roadways in real-time. The conventional global positioning system is ubiquitous and essentially free to use but it produces impractically large position errors. This study evaluated the improvement in precision achievable by augmenting the conventional geo-fence system with a standard speed bump or an existing anomaly at a pre-determined position to establish a reference inertial marker. The speed sensor subsequently generates position tags for the remaining inertial samples by computing their path distances relative to the reference position. The error model and a case study using smartphones to emulate connected vehicles revealed that the precision in localization improves from tens of metres to sub-centimetre levels, and the accuracy of measuring localized roughness more than doubles. The research results demonstrate that transportation agencies will benefit from using the connected vehicle method to achieve precision and accuracy levels that are comparable to existing laser-based inertial profilers. (paper)

  13. Criminal profiling as expert witness evidence: The implications of the profiler validity research.

    Science.gov (United States)

    Kocsis, Richard N; Palermo, George B

    The use and development of the investigative tool colloquially known as criminal profiling has steadily increased over the past five decades throughout the world. Coupled with this growth has been a diversification in the suggested range of applications for this technique. Possibly the most notable of these has been the attempted transition of the technique from a tool intended to assist police investigations into a form of expert witness evidence admissible in legal proceedings. Whilst case law in various jurisdictions has considered with mutual disinclination the evidentiary admissibility of criminal profiling, a disjunction has evolved between these judicial examinations and the scientifically vetted research testing the accuracy (i.e., validity) of the technique. This article offers an analysis of the research directly testing the validity of the criminal profiling technique and the extant legal principles considering its evidentiary admissibility. This analysis reveals that research findings concerning the validity of criminal profiling are surprisingly compatible with the extant legal principles. The overall conclusion is that a discrete form of crime behavioural analysis is supported by the profiler validity research and could be regarded as potentially admissible expert witness evidence. Finally, a number of theoretical connections are also identified concerning the skills and qualifications of individuals who may feasibly provide such expert testimony. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Structural Connectivity of the Developing Human Amygdala

    Science.gov (United States)

    Saygin, Zeynep M.; Osher, David E.; Koldewyn, Kami; Martin, Rebecca E.; Finn, Amy; Saxe, Rebecca; Gabrieli, John D.E.; Sheridan, Margaret

    2015-01-01

    A large corpus of research suggests that there are changes in the manner and degree to which the amygdala supports cognitive and emotional function across development. One possible basis for these developmental differences could be the maturation of amygdalar connections with the rest of the brain. Recent functional connectivity studies support this conclusion, but the structural connectivity of the developing amygdala and its different nuclei remains largely unstudied. We examined age related changes in the DWI connectivity fingerprints of the amygdala to the rest of the brain in 166 individuals of ages 5-30. We also developed a model to predict age based on individual-subject amygdala connectivity, and identified the connections that were most predictive of age. Finally, we segmented the amygdala into its four main nucleus groups, and examined the developmental changes in connectivity for each nucleus. We observed that with age, amygdalar connectivity becomes increasingly sparse and localized. Age related changes were largely localized to the subregions of the amygdala that are implicated in social inference and contextual memory (the basal and lateral nuclei). The central nucleus’ connectivity also showed differences with age but these differences affected fewer target regions than the basal and lateral nuclei. The medial nucleus did not exhibit any age related changes. These findings demonstrate increasing specificity in the connectivity patterns of amygdalar nuclei across age. PMID:25875758

  15. Convolution based profile fitting

    International Nuclear Information System (INIS)

    Kern, A.; Coelho, A.A.; Cheary, R.W.

    2002-01-01

    Full text: In convolution based profile fitting, profiles are generated by convoluting functions together to form the observed profile shape. For a convolution of 'n' functions this process can be written as, Y(2θ)=F 1 (2θ)x F 2 (2θ)x... x F i (2θ)x....xF n (2θ). In powder diffractometry the functions F i (2θ) can be interpreted as the aberration functions of the diffractometer, but in general any combination of appropriate functions for F i (2θ) may be used in this context. Most direct convolution fitting methods are restricted to combinations of F i (2θ) that can be convoluted analytically (e.g. GSAS) such as Lorentzians, Gaussians, the hat (impulse) function and the exponential function. However, software such as TOPAS is now available that can accurately convolute and refine a wide variety of profile shapes numerically, including user defined profiles, without the need to convolute analytically. Some of the most important advantages of modern convolution based profile fitting are: 1) virtually any peak shape and angle dependence can normally be described using minimal profile parameters in laboratory and synchrotron X-ray data as well as in CW and TOF neutron data. This is possible because numerical convolution and numerical differentiation is used within the refinement procedure so that a wide range of functions can easily be incorporated into the convolution equation; 2) it can use physically based diffractometer models by convoluting the instrument aberration functions. This can be done for most laboratory based X-ray powder diffractometer configurations including conventional divergent beam instruments, parallel beam instruments, and diffractometers used for asymmetric diffraction. It can also accommodate various optical elements (e.g. multilayers and monochromators) and detector systems (e.g. point and position sensitive detectors) and has already been applied to neutron powder diffraction systems (e.g. ANSTO) as well as synchrotron based

  16. Country profile: Hungary

    Energy Technology Data Exchange (ETDEWEB)

    1991-09-01

    Country Profile: Hungary has been prepared as a background document for use by US Government agencies and US businesses interested in becoming involved with the new democracies of Eastern Europe as they pursue sustainable economic development. The focus of the Profile is on energy and highlights information on Hungary`s energy supply, demand, and utilization. It identifies patterns of energy usage in the important economic sectors, especially industry, and provides a preliminary assessment for opportunities to improve efficiencies in energy production, distribution and use by introducing more efficient technologies. The use of more efficient technologies would have the added benefit of reducing the environmental impact which, although is not the focus of the report, is an issue that effects energy choices. The Profile also presents considerable economic information, primarily in the context of how economic restructuring may affect energy supply, demand, and the introduction of more efficient technologies.

  17. Country profile: Hungary

    Energy Technology Data Exchange (ETDEWEB)

    1991-09-01

    Country Profile: Hungary has been prepared as a background document for use by US Government agencies and US businesses interested in becoming involved with the new democracies of Eastern Europe as they pursue sustainable economic development. The focus of the Profile is on energy and highlights information on Hungary's energy supply, demand, and utilization. It identifies patterns of energy usage in the important economic sectors, especially industry, and provides a preliminary assessment for opportunities to improve efficiencies in energy production, distribution and use by introducing more efficient technologies. The use of more efficient technologies would have the added benefit of reducing the environmental impact which, although is not the focus of the report, is an issue that effects energy choices. The Profile also presents considerable economic information, primarily in the context of how economic restructuring may affect energy supply, demand, and the introduction of more efficient technologies.

  18. Qualitative Value Profiling

    DEFF Research Database (Denmark)

    Duus, Henrik Johannsen; Bjerre, Mogens

    2015-01-01

    allows the development of 1) profiles of the target country in which operations are to take place, 2) profiles of the buying center (i.e. the group of decision makers) in the partner company, and 3) profiles of the product/service offering. It also allows the development of a semantic scaling method...... for deeper analysis of all involved factors. This paper presents the method and compares and contrasts it with other similar methods like the PESTELE method known from corporate strategy, the STEEPAL method known from scenario analysis, and the Politics-Institutions-Economy (PIE) framework known from...... International Business. This comparison suggests that QVP on most accounts provides deeper insights than alternative methods and thus lays the foundation for better strategic planning in international business-to-business markets. Hence, it is a valuable addition to the toolbox of business strategists...

  19. Detonation Wave Profile

    Energy Technology Data Exchange (ETDEWEB)

    Menikoff, Ralph [Los Alamos National Laboratory

    2015-12-14

    The Zel’dovich-von Neumann-Doering (ZND) profile of a detonation wave is derived. Two basic assumptions are required: i. An equation of state (EOS) for a partly burned explosive; P(V, e, λ). ii. A burn rate for the reaction progress variable; d/dt λ = R(V, e, λ). For a steady planar detonation wave the reactive flow PDEs can be reduced to ODEs. The detonation wave profile can be determined from an ODE plus algebraic equations for points on the partly burned detonation loci with a specified wave speed. Furthermore, for the CJ detonation speed the end of the reaction zone is sonic. A solution to the reactive flow equations can be constructed with a rarefaction wave following the detonation wave profile. This corresponds to an underdriven detonation wave, and the rarefaction is know as a Taylor wave.

  20. Courant algebroid connections and string effective actions

    OpenAIRE

    Jurčo, B.

    2017-01-01

    Courant algebroids are a natural generalization of quadratic Lie algebras, appearing in various contexts in mathematical physics. A connection on a Courant algebroid gives an analogue of a covariant derivative compatible with a given fiber-wise metric. Imposing further conditions resembling standard Levi-Civita connections, one obtains a class of connections whose curvature tensor in certain cases gives a new geometrical description of equations of motion of low energy effective action of str...

  1. Robust motion estimation using connected operators

    OpenAIRE

    Salembier Clairon, Philippe Jean; Sanson, H

    1997-01-01

    This paper discusses the use of connected operators for robust motion estimation The proposed strategy involves a motion estimation step extracting the dominant motion and a ltering step relying on connected operators that remove objects that do not fol low the dominant motion. These two steps are iterated in order to obtain an accurate motion estimation and a precise de nition of the objects fol lowing this motion This strategy can be applied on the entire frame or on individual connected c...

  2. Projective Connections and the Algebra of Densities

    International Nuclear Information System (INIS)

    George, Jacob

    2008-01-01

    Projective connections first appeared in Cartan's papers in the 1920's. Since then they have resurfaced periodically in, for example, integrable systems and perhaps most recently in the context of so called projectively equivariant quantisation. We recall the notion of projective connection and describe its relation with the algebra of densities on a manifold. In particular, we construct a Laplace-type operator on functions using a Thomas projective connection and a symmetric contravariant tensor of rank 2 ('upper metric').

  3. Structural Connectivity Asymmetry in the Neonatal Brain

    OpenAIRE

    Ratnarajah, Nagulan; Rifkin-Graboi, Anne; Fortier, Marielle V.; Chong, Yap Seng; Kwek, Kenneth; Saw, Seang-Mei; Godfrey, Keith M; Gluckman, Peter D.; Meaney, Michael J.; Qiu, Anqi

    2013-01-01

    Asymmetry of the neonatal brain is not yet understood at the level of structural connectivity. We utilized DTI deterministic tractography and structural network analysis based on graph theory to determine the pattern of structural connectivity asymmetry in 124 normal neonates. We tracted white matter axonal pathways characterizing interregional connections among brain regions and inferred asymmetry in left and right anatomical network properties. Our findings revealed that in neonates, small-...

  4. Constructing Data Curation Profiles

    Directory of Open Access Journals (Sweden)

    Michael Witt

    2009-12-01

    Full Text Available This paper presents a brief literature review and then introduces the methods, design, and construction of the Data Curation Profile, an instrument that can be used to provide detailed information on particular data forms that might be curated by an academic library. These data forms are presented in the context of the related sub-disciplinary research area, and they provide the flow of the research process from which these data are generated. The profiles also represent the needs for data curation from the perspective of the data producers, using their own language. As such, they support the exploration of data curation across different research domains in real and practical terms. With the sponsorship of the Institute of Museum and Library Services, investigators from Purdue University and the University of Illinois interviewed 19 faculty subjects to identify needs for discovery, access, preservation, and reuse of their research data. For each subject, a profile was constructed that includes information about his or her general research, data forms and stages, value of data, data ingest, intellectual property, organization and description of data, tools, interoperability, impact and prestige, data management, and preservation. Each profile also presents a specific dataset supplied by the subject to serve as a concrete example. The Data Curation Profiles are being published to a public wiki for questions and discussion, and a blank template will be disseminated with guidelines for others to create and share their own profiles. This study was conducted primarily from the viewpoint of librarians interacting with faculty researchers; however, it is expected that these findings will complement a wide variety of data curation research and practice outside of librarianship and the university environment.

  5. Equilibrium shoreface profiles

    DEFF Research Database (Denmark)

    Aagaard, Troels; Hughes, Michael G

    2017-01-01

    Large-scale coastal behaviour models use the shoreface profile of equilibrium as a fundamental morphological unit that is translated in space to simulate coastal response to, for example, sea level oscillations and variability in sediment supply. Despite a longstanding focus on the shoreface...... profile and its relevance to predicting coastal response to changing environmental conditions, the processes and dynamics involved in shoreface equilibrium are still not fully understood. Here, we apply a process-based empirical sediment transport model, combined with morphodynamic principles to provide......; there is no tuning or calibration and computation times are short. It is therefore easily implemented with repeated iterations to manage uncertainty....

  6. Lifespan anxiety is reflected in human amygdala cortical connectivity

    Science.gov (United States)

    He, Ye; Xu, Ting; Zhang, Wei

    2016-01-01

    Abstract The amygdala plays a pivotal role in processing anxiety and connects to large‐scale brain networks. However, intrinsic functional connectivity (iFC) between amygdala and these networks has rarely been examined in relation to anxiety, especially across the lifespan. We employed resting‐state functional MRI data from 280 healthy adults (18–83.5 yrs) to elucidate the relationship between anxiety and amygdala iFC with common cortical networks including the visual network, somatomotor network, dorsal attention network, ventral attention network, limbic network, frontoparietal network, and default network. Global and network‐specific iFC were separately computed as mean iFC of amygdala with the entire cerebral cortex and each cortical network. We detected negative correlation between global positive amygdala iFC and trait anxiety. Network‐specific associations between amygdala iFC and anxiety were also detectable. Specifically, the higher iFC strength between the left amygdala and the limbic network predicted lower state anxiety. For the trait anxiety, left amygdala anxiety–connectivity correlation was observed in both somatomotor and dorsal attention networks, whereas the right amygdala anxiety–connectivity correlation was primarily distributed in the frontoparietal and ventral attention networks. Ventral attention network exhibited significant anxiety–gender interactions on its iFC with amygdala. Together with findings from additional vertex‐wise analysis, these data clearly indicated that both low‐level sensory networks and high‐level associative networks could contribute to detectable predictions of anxiety behaviors by their iFC profiles with the amygdala. This set of systems neuroscience findings could lead to novel functional network models on neural correlates of human anxiety and provide targets for novel treatment strategies on anxiety disorders. Hum Brain Mapp 37:1178–1193, 2016. © 2015 The Authors Human Brain Mapping

  7. Synchronization from Second Order Network Connectivity Statistics

    Science.gov (United States)

    Zhao, Liqiong; Beverlin, Bryce; Netoff, Theoden; Nykamp, Duane Q.

    2011-01-01

    We investigate how network structure can influence the tendency for a neuronal network to synchronize, or its synchronizability, independent of the dynamical model for each neuron. The synchrony analysis takes advantage of the framework of second order networks, which defines four second order connectivity statistics based on the relative frequency of two-connection network motifs. The analysis identifies two of these statistics, convergent connections, and chain connections, as highly influencing the synchrony. Simulations verify that synchrony decreases with the frequency of convergent connections and increases with the frequency of chain connections. These trends persist with simulations of multiple models for the neuron dynamics and for different types of networks. Surprisingly, divergent connections, which determine the fraction of shared inputs, do not strongly influence the synchrony. The critical role of chains, rather than divergent connections, in influencing synchrony can be explained by their increasing the effective coupling strength. The decrease of synchrony with convergent connections is primarily due to the resulting heterogeneity in firing rates. PMID:21779239

  8. Synchronization from second order network connectivity statistics

    Directory of Open Access Journals (Sweden)

    Liqiong eZhao

    2011-07-01

    Full Text Available We investigate how network structure can influence the tendency for a neuronal network to synchronize, or its synchronizability, independent of the dynamical model for each neuron. The synchrony analysis takes advantage of the framework of second order networks (SONETs, which defines four second order connectivity statistics based on the relative frequency of two-connection network motifs. The analysis identifies two of these statistics, convergent connections and chain connections, as highly influencing the synchrony. Simulations verify that synchrony decreases with the frequency of convergent connections and increases with the frequency of chain connections. These trends persist with simulations of multiple models for the neuron dynamics and for different types of networks. Surprisingly, divergent connections, which determine the fraction of shared inputs, do not strongly influence the synchrony. The critical role of chains, rather than divergent connections, in influencing synchrony can be explained by a pool and redistribute mechanism. The pooling of many inputs averages out independent fluctuations, amplifying weak correlations in the inputs. With increased chain connections, neurons with many inputs tend to have many outputs. Hence, chains ensure that the amplified correlations in the neurons with many inputs are redistributed throughout the network, enhancing the development of synchrony across the network.

  9. Effect of ionizing radiations on connective tissue

    International Nuclear Information System (INIS)

    Altman, K.I.; Gerber, G.B.

    1980-01-01

    The effects of ionizing radiations on connective tissue in lung, heart, vasculature, kidney, skin, and skeletal tissues are reviewed. Special emphasis is given to the effect of ionizing radiations on vasculo-connective tissue and fibrotic changes following radiation-induced injury to organs and tissues. In order to put the subject matter in proper prospective, the general biochemistry, physiology, and pathology of connective tissue is reviewed briefly together with the participation of connective tissue in disease. The review closes with an assessment of future problems and an enumeration and discussion of important, as yet unanswered questions

  10. Essential Connectivity Areas - CEHC, (Raster) [ds620

    Data.gov (United States)

    California Natural Resource Agency — The California Department of Transportation (Caltrans) and California Department of Fish and Game (CDFG) commissioned the California Essential Habitat Connectivity...

  11. Connecting multimodality in human communication

    Directory of Open Access Journals (Sweden)

    Christina eRegenbogen

    2013-11-01

    Full Text Available A successful reciprocal evaluation of social signals serves as a prerequisite for social coherence and empathy. In a previous fMRI study we studied naturalistic communication situations by presenting video clips to our participants and recording their behavioral responses regarding empathy and its components. In two conditions, all three channels transported congruent emotional or neutral information, respectively. Three conditions selectively presented two emotional channels and one neutral channel and were thus bimodally emotional. We reported channel-specific emotional contributions in modality-related areas, elicited by dynamic video clips with varying combinations of emotionality in facial expressions, prosody, and speech content. However, to better understand the underlying mechanisms accompanying a naturalistically displayed human social interaction in some key regions that presumably serve as specific processing hubs for facial expressions, prosody, and speech content, we pursued a reanalysis of the data. In addition to this specificity of these regions to information channels we demonstrated that they were also sensitive to variations of the respective emotional content.Here, we focused on two different descriptions of temporal characteristics within these three modality-related regions (right fusiform gyrus (FFG, left auditory cortex (AC, left angular gyrus (AG and left dorsomedial prefrontal cortex (dmPFC. By means of a finite impulse response (FIR analysis within each of the three regions we examined the post-stimulus time-courses as a description of the temporal characteristics of the BOLD response during the video clips. Second, effective connectivity between these areas and the left dmPFC was analyzed using dynamic causal modeling (DCM in order to describe condition-related modulatory influences on the coupling between these regions. The FIR analysis showed initially diminished activation in bimodally emotional conditions but

  12. Aberrant Intrinsic Activity and Connectivity in Cognitively Normal Parkinson's Disease.

    Science.gov (United States)

    Harrington, Deborah L; Shen, Qian; Castillo, Gabriel N; Filoteo, J Vincent; Litvan, Irene; Takahashi, Colleen; French, Chelsea

    2017-01-01

    Disturbances in intrinsic activity during resting-state functional MRI (rsfMRI) are common in Parkinson's disease (PD), but have largely been studied in a priori defined subnetworks. The cognitive significance of abnormal intrinsic activity is also poorly understood, as are abnormalities that precede the onset of mild cognitive impairment. To address these limitations, we leveraged three different analytic approaches to identify disturbances in rsfMRI metrics in 31 cognitively normal PD patients (PD-CN) and 30 healthy adults. Subjects were screened for mild cognitive impairment using the Movement Disorders Society Task Force Level II criteria. Whole-brain data-driven analytic approaches first analyzed the amplitude of low-frequency intrinsic fluctuations (ALFF) and regional homogeneity (ReHo), a measure of local connectivity amongst functionally similar regions. We then examined if regional disturbances in these metrics altered functional connectivity with other brain regions. We also investigated if abnormal rsfMRI metrics in PD-CN were related to brain atrophy and executive, visual organization, and episodic memory functioning. The results revealed abnormally increased and decreased ALFF and ReHo in PD-CN patients within the default mode network (posterior cingulate, inferior parietal cortex, parahippocampus, entorhinal cortex), sensorimotor cortex (primary motor, pre/post-central gyrus), basal ganglia (putamen, caudate), and posterior cerebellar lobule VII, which mediates cognition. For default mode network regions, we also observed a compound profile of altered ALFF and ReHo. Most regional disturbances in ALFF and ReHo were associated with strengthened long-range interactions in PD-CN, notably with regions in different networks. Stronger long-range functional connectivity in PD-CN was also partly expanded to connections that were outside the networks of the control group. Abnormally increased activity and functional connectivity appeared to have a pathological

  13. Genome-wide strategies identify downstream target genes of chick connective tissue-associated transcription factors.

    Science.gov (United States)

    Orgeur, Mickael; Martens, Marvin; Leonte, Georgeta; Nassari, Sonya; Bonnin, Marie-Ange; Börno, Stefan T; Timmermann, Bernd; Hecht, Jochen; Duprez, Delphine; Stricker, Sigmar

    2018-03-29

    Connective tissues support organs and play crucial roles in development, homeostasis and fibrosis, yet our understanding of their formation is still limited. To gain insight into the molecular mechanisms of connective tissue specification, we selected five zinc-finger transcription factors - OSR1, OSR2, EGR1, KLF2 and KLF4 - based on their expression patterns and/or known involvement in connective tissue subtype differentiation. RNA-seq and ChIP-seq profiling of chick limb micromass cultures revealed a set of common genes regulated by all five transcription factors, which we describe as a connective tissue core expression set. This common core was enriched with genes associated with axon guidance and myofibroblast signature, including fibrosis-related genes. In addition, each transcription factor regulated a specific set of signalling molecules and extracellular matrix components. This suggests a concept whereby local molecular niches can be created by the expression of specific transcription factors impinging on the specification of local microenvironments. The regulatory network established here identifies common and distinct molecular signatures of limb connective tissue subtypes, provides novel insight into the signalling pathways governing connective tissue specification, and serves as a resource for connective tissue development. © 2018. Published by The Company of Biologists Ltd.

  14. Does resting-state connectivity reflect depressive rumination? A tale of two analyses.

    Science.gov (United States)

    Berman, Marc G; Misic, Bratislav; Buschkuehl, Martin; Kross, Ethan; Deldin, Patricia J; Peltier, Scott; Churchill, Nathan W; Jaeggi, Susanne M; Vakorin, Vasily; McIntosh, Anthony R; Jonides, John

    2014-12-01

    Major Depressive Disorder (MDD) is characterized by rumination. Prior research suggests that resting-state brain activation reflects rumination when depressed individuals are not task engaged. However, no study has directly tested this. Here we investigated whether resting-state epochs differ from induced ruminative states for healthy and depressed individuals. Most previous research on resting-state networks comes from seed-based analyses with the posterior cingulate cortex (PCC). By contrast, we examined resting state connectivity by using the complete multivariate connectivity profile (i.e., connections across all brain nodes) and by comparing these results to seeded analyses. We find that unconstrained resting-state intervals differ from active rumination states in strength of connectivity and that overall connectivity was higher for healthy vs. depressed individuals. Relationships between connectivity and subjective mood (i.e., behavior) were strongly observed during induced rumination epochs. Furthermore, connectivity patterns that related to subjective mood were strikingly different for MDD and healthy control (HC) groups suggesting different mood regulation mechanisms. Copyright © 2014 Elsevier Inc. All rights reserved.

  15. Economy Profile of Argentina

    OpenAIRE

    World Bank Group

    2017-01-01

    Doing Business 2018 is the 15th in a series of annual reports investigating the regulations that enhance business activity and those that constrain it. This economy profile presents the Doing Business indicators for Argentina. Doing Business presents quantitative indicators on business regulation and the protection of property rights that can be compared across 190 economies; for 2018 Arge...

  16. Economy Profile of Estonia

    OpenAIRE

    World Bank Group

    2017-01-01

    Doing Business 2018 is the 15th in a series of annual reports investigating the regulations that enhance business activity and those that constrain it. This economy profile presents the Doing Business indicators for Estonia. Doing Business presents quantitative indicators on business regulation and the protection of property rights that can be compared across 190 economies; for 2018 Estonia ...

  17. Economy Profile of Australia

    OpenAIRE

    World Bank Group

    2017-01-01

    Doing Business 2018 is the 15th in a series of annual reports investigating the regulations that enhance business activity and those that constrain it. This economy profile presents the Doing Business indicators for Australia. Doing Business presents quantitative indicators on business regulation and the protection of property rights that can be compared across 190 economies; for 2018 Aust...

  18. Profiling & Utilizing Learning Style.

    Science.gov (United States)

    Keefe, James W., Ed.

    The purpose of the National Association of Secondary School Principals (NASSP) Learning Style Profile is to provide educators with a well-validated and easy-to-use instrument for diagnosing the cognitive styles, perceptual response tendencies, and study/instructional preferences of middle level and senior high school students. The Learning Style…

  19. Country Profiles, Malaysia.

    Science.gov (United States)

    Marzuki, Ariffin Bin; Peng, J. Y.

    A profile of Malaysia is sketched in this paper. Emphasis is placed on the nature, scope, and accomplishments of population activities in the country. Topics and sub-topics include: location and description of the country; population (size, growth patterns, age structure, urban/rural distribution, ethnic and religious composition, migration,…

  20. Economy Profile of Bolivia

    OpenAIRE

    World Bank Group

    2017-01-01

    Doing Business 2018 is the 15th in a series of annual reports investigating the regulations that enhance business activity and those that constrain it. This economy profile presents the Doing Business indicators for Bolivia. Doing Business presents quantitative indicators on business regulation and the protection of property rights that can be compared across 190 economies; for 2018 Bolivia ...

  1. Culinary Arts Profile.

    Science.gov (United States)

    Missouri Univ., Columbia. Instructional Materials Lab.

    This chart is intended for use in documenting the fact that a student participating in a culinary arts program has achieved the performance standards specified in the Missouri Competency Profile for culinary arts. The chart includes space for recording basic student and instructor information and the student's on-the-job training and work…

  2. Beam profile monitor

    International Nuclear Information System (INIS)

    Krausse, G.J.; Gram, P.A.M.

    1978-05-01

    A system used to monitor secondary beam profiles at the LAMPF Linac for channel tune-up and diagnostics is described. The multiwire proportional chamber design is discussed, and descriptions and drawings of the gate card, the amplifier/multiplexer card, the output amplifier card, and the overall system are given

  3. Simple beam profile monitor

    Energy Technology Data Exchange (ETDEWEB)

    Gelbart, W.; Johnson, R. R.; Abeysekera, B. [ASD Inc. Garden Bay, BC (Canada); Best Theratronics Ltd Ottawa Ontario (Canada); PharmaSpect Ltd., Burnaby BC (Canada)

    2012-12-19

    An inexpensive beam profile monitor is based on the well proven rotating wire method. The monitor can display beam position and shape in real time for particle beams of most energies and beam currents up to 200{mu}A. Beam shape, position cross-section and other parameters are displayed on a computer screen.

  4. Modeling shoreface profile evolution

    NARCIS (Netherlands)

    Stive, M.J.F.; De Vriend, H.J.

    1995-01-01

    Current knowledge of hydro-, sediment and morpho-dynamics in the shoreface environment is insufficient to undertake shoreface-profile evolution modelling on the basis of first physical principles. We propose a simple, panel-type model to map observed behaviour. The internal dynamics are determined

  5. Modelling shoreface profile evolution

    NARCIS (Netherlands)

    Stive, Marcel J.F.; de Vriend, Huib J.

    1995-01-01

    Current knowledge of hydro-, sediment and morpho-dynamics in the shoreface environment is insufficient to undertake shoreface-profile evolution modelling on the basis of first physical principles. We propose a simple, panel-type model to map observed behaviour. The internal dynamics are determined

  6. A temperature profiler

    Digital Repository Service at National Institute of Oceanography (India)

    Peshwe, V.B.; Desa, E.

    An instrument developed for measuring temperature profiles at sea in depth or time scales is described. PC-based programming offers flexibility in setting up the instrument for the mode of operation prior to each cast. A real time clock built...

  7. Country Demographic Profiles: Thailand.

    Science.gov (United States)

    Bureau of the Census (DOC), Suitland, MD. Population Div.

    This profile of the population of Thailand contains 35 tables of selected demographic information, including size of population and estimates of fertility and mortality, beginning in 1950. An adjusted distribution of the population by age and sex is given for the latest census year, as well as for 1976. Projections of the number of women of…

  8. Polysome Profile Analysis - Yeast

    Czech Academy of Sciences Publication Activity Database

    Pospíšek, M.; Valášek, Leoš Shivaya

    2013-01-01

    Roč. 530, č. 2013 (2013), s. 173-181 ISSN 0076-6879 Institutional support: RVO:61388971 Keywords : grow yeast cultures * polysome profile analysis * sucrose density gradient centrifugation Subject RIV: CE - Biochemistry Impact factor: 2.194, year: 2013

  9. A Danish Profiling System

    DEFF Research Database (Denmark)

    Rosholm, Michael; Staghøj, Jonas; Svarer, Michael

    2006-01-01

    This paper describes the statistical model used for profiling new unemployed workers in Denmark. When a worker – during his or her first six months in unemployment – enters the employment office for the first time, this model predicts whether or not he or she will be unemployed for more than six ...

  10. Crash injury risk behavior in adolescent latino males: the power of friends and relational connections.

    Science.gov (United States)

    Vaca, Federico E; Anderson, Craig L

    2011-01-01

    The adolescent Latino male mortality profile is an anomaly when compared to an otherwise more favorable overall U.S. Latino population mortality profile. Motor vehicle crash fatalities bear a considerable proportion of mortality burden in this vulnerable population. Friend influence and relational connection are two contextual domains that may mediate crash injury risk behavior in these adolescents. Our study goal was to assess the role of friend influence over time and relational connections associated with crash injury risk behavior (CIRB) in adolescent Latino males. Waves I and II data from the National Longitudinal Study of Adolescent Health were used. Scale of CIRB, and three relational connections; school connectedness, parent connectedness, and expectation of academic success were developed and tested. Friend nomination data were available and the index student responses were linked to friend responses. Linear regression was used to assess the relationship of relational connections and friend CIRB on index student CIRB at wave I and II. Longitudinal analysis did not show significant evidence for friend influence among adolescent Latino males on CIRB. The best predictor of CIRB at wave II for adolescent Latino males was their CIRB at wave I. Relational connections were important yet exaggerated cross-sectionally but their effect was substantially attenuated longitudinally. The lack of friend influence on CIRB for adolescent Latino males may be specific to this demographic group or characteristic of the sample studied. Prevention strategies that focus on modulating friend influence in adolescent Latino males may not yield the desired prevention effects on CIRB.

  11. [Safety profile of dolutegravir].

    Science.gov (United States)

    Rivero, Antonio; Domingo, Pere

    2015-03-01

    Integrase inhibitors are the latest drug family to be added to the therapeutic arsenal against human immunodeficiency virus infection. Drugs in this family that do not require pharmacological boosting are characterized by a very good safety profile. The latest integrase inhibitor to be approved for use is dolutegravir. In clinical trials, dolutegravir has shown an excellent tolerability profile, both in antiretroviral-naïve and previously treated patients. Discontinuation rates due to adverse effects were 2% and 3%, respectively. The most frequent adverse effects were nausea, headache, diarrhea and sleep disturbance. A severe hypersensitivity reaction has been reported in only one patient. In patients coinfected with hepatropic viruses, the safety profile is similar to that in patients without coinfection. The lipid profile of dolutegravir is similar to that of raltegravir and superior to those of Atripla® and darunavir/ritonavir. Dolutegravir induces an early, predictable and non-progressive increase in serum creatinine of around 10% of baseline values in treatment-naïve patients and of 14% in treatment-experienced patients. This increase is due to inhibition of tubular creatinine secretion through the OCT2 receptor and does not lead to a real decrease in estimated glomerular filtration rate with algorithms that include serum creatinine. The effect of the combination of dolutegravir plus Kivexa(®) on biomarkers of bone remodeling is lower than that of Atripla(®). Dolutegravir has an excellent tolerability profile with no current evidence of long-term adverse effects. Its use is accompanied by an early and non-progressive increase in serum creatinine due to OCT2 receptor inhibition. In combination with abacavir/lamivudine, dolutegravir has a lower impact than enofovir/emtricitabine/efavirenz on bone remodelling markers. Copyright © 2015 Elsevier España, S.L.U. All rights reserved.

  12. 47 CFR 54.506 - Internal connections.

    Science.gov (United States)

    2010-10-01

    ... instructional building of a school or to a non-administrative building of a library. Internal connections do not... SERVICE Universal Service Support for Schools and Libraries § 54.506 Internal connections. (a) A service... necessary to transport information within one or more instructional buildings of a single school campus or...

  13. Aberrant orbitofrontal connectivity in marijuana smoking adolescents

    Directory of Open Access Journals (Sweden)

    Melissa Patricia Lopez-Larson

    2015-12-01

    Discussion: Findings indicate atypical OFC functional connectivity patterns in attentional/executive, motor and reward networks in adolescents with heavy MJ use. These anomalies may be related to suboptimal decision making capacities and increased impulsivity. Results also suggest different OFC connectivity patterns may be present in adolescents with early onset of MJ use and high lifetime exposure to MJ.

  14. Centrifugal separator cascade connected in zigzag manner

    International Nuclear Information System (INIS)

    Kai, Tsunetoshi; Inoue, Yoshiya; Oya, Akio; Nagakura, Masaaki.

    1974-01-01

    Object: To effectively accommodate centrifugal separators of the entire cascade within the available space in a plant by freely selecting perpendicular direction of connection of the centrifugal separator. Structure: Centrifugal separators are connected in zigzag fashion by using a single header for each stage so that in a rectangular shape the entire cascade is arranged. (Kamimura, M.)

  15. Are we connected? : Ports in Global Networks

    NARCIS (Netherlands)

    R.A. Zuidwijk (Rob)

    2015-01-01

    markdownabstractAbstract Global supply chains are built on organizational, information, and logistics networks. Ports are connected via these networks and also need to connect these networks. Synchromodality is an innovative concept for container transportation, and the port plays an important

  16. Connections between quantum chromodynamics and condensed

    Indian Academy of Sciences (India)

    Using examples we discuss some of the connections between the two fields and show how progress can be made by exploiting this connection. Some of the challenges that remain in ... Current Issue : Vol. 90, Issue 6. Current Issue Volume 90 ...

  17. Countering oversegmentation in partitioning-based connectivities

    NARCIS (Netherlands)

    Ouzounis, Georgios K.; Wilkinson, Michael H.F.

    2005-01-01

    A new theoretical development is presented for handling the over-segmentation problem in partitioning-based connected openings. The definition we propose treats singletons generated with the earlier method, as elements of a larger connected component. Unlike the existing formalism, this new method

  18. Connecting Representations: Using Predict, Check, Explain

    Science.gov (United States)

    Roy, George J.; Fueyo, Vivian; Vahey, Philip; Knudsen, Jennifer; Rafanan, Ken; Lara-Meloy, Teresa

    2016-01-01

    Although educators agree that making connections with the real world, as advocated by "Principles to Actions: Ensuring Mathematical Success for All" (NCTM 2014), is important, making such connections while addressing important mathematics is elusive. The authors have found that math content coupled with the instructional strategy of…

  19. Voltage Quality of Grid Connected Wind Turbines

    DEFF Research Database (Denmark)

    Chen, Zhe; Blaabjerg, Frede; Sun, Tao

    2004-01-01

    Grid connected wind turbines may cause quality problems, such as voltage variation and flicker. This paper discusses the voltage variation and flicker emission of grid connected wind turbines with doubly-fed induction generators. A method to compensate flicker by using a voltage source converter...

  20. Simple clamped connection for bamboo truss systems

    NARCIS (Netherlands)

    Blok, R.

    2016-01-01

    “How to make fast and simple tension connections for truss systems?” The Solution: The innovation is a connection that uses only widely available base components (boltsand threaded steel bars) and simple hand tools to install it. With a handsaw and aspanner, the bamboo stems can be combined into to

  1. IDRC Connect | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    2015-07-20

    All IDRC-funded researchers have access to IDRC Connect, our project portal and collaborative workspace. For projects approved after July 20, 2015, IDRC Connect must be used to submit technical reports project outputs funding requests for open access journal publishing charges You need a password to access IDRC ...

  2. Connecting Functions in Geometry and Algebra

    Science.gov (United States)

    Steketee, Scott; Scher, Daniel

    2016-01-01

    One goal of a mathematics education is that students make significant connections among different branches of mathematics. Connections--such as those between arithmetic and algebra, between two-dimensional and three-dimensional geometry, between compass-and-straight-edge constructions and transformations, and between calculus and analytic…

  3. Natural Connections on Riemannian Product Manifolds

    OpenAIRE

    Gribacheva, Dobrinka

    2011-01-01

    A Riemannian almost product manifold with integrable almost product structure is called a Riemannian product manifold. In the present paper the natural connections on such manifolds are studied, i.e. the linear connections preserving the almost product structure and the Riemannian metric.

  4. Connectivity: Performance Portable Algorithms for graph connectivity v. 0.1

    Energy Technology Data Exchange (ETDEWEB)

    2017-09-21

    Graphs occur in several places in real world from road networks, social networks and scientific simulations. Connectivity is a graph analysis software to graph connectivity in modern architectures like multicore CPUs, Xeon Phi and GPUs.

  5. Directional connectivity in hydrology and ecology

    Science.gov (United States)

    Larsen, Laurel G.; Choi, Jungyill; Nungesser, Martha K.; Harvey, Judson W.

    2012-01-01

    Quantifying hydrologic and ecological connectivity has contributed to understanding transport and dispersal processes and assessing ecosystem degradation or restoration potential. However, there has been little synthesis across disciplines. The growing field of ecohydrology and recent recognition that loss of hydrologic connectivity is leading to a global decline in biodiversity underscore the need for a unified connectivity concept. One outstanding need is a way to quantify directional connectivity that is consistent, robust to variations in sampling, and transferable across scales or environmental settings. Understanding connectivity in a particular direction (e.g., streamwise, along or across gradient, between sources and sinks, along cardinal directions) provides critical information for predicting contaminant transport, planning conservation corridor design, and understanding how landscapes or hydroscapes respond to directional forces like wind or water flow. Here we synthesize progress on quantifying connectivity and develop a new strategy for evaluating directional connectivity that benefits from use of graph theory in ecology and percolation theory in hydrology. The directional connectivity index (DCI) is a graph-theory based, multiscale metric that is generalizable to a range of different structural and functional connectivity applications. It exhibits minimal sensitivity to image rotation or resolution within a given range and responds intuitively to progressive, unidirectional change. Further, it is linearly related to the integral connectivity scale length—a metric common in hydrology that correlates well with actual fluxes—but is less computationally challenging and more readily comparable across different landscapes. Connectivity-orientation curves (i.e., directional connectivity computed over a range of headings) provide a quantitative, information-dense representation of environmental structure that can be used for comparison or detection of

  6. Directional connectivity in hydrology and ecology.

    Science.gov (United States)

    Larsen, Laurel G; Choi, Jungyill; Nungesser, Martha K; Harvey, Judson W

    2012-12-01

    Quantifying hydrologic and ecological connectivity has contributed to understanding transport and dispersal processes and assessing ecosystem degradation or restoration potential. However, there has been little synthesis across disciplines. The growing field of ecohydrology and recent recognition that loss of hydrologic connectivity is leading to a global decline in biodiversity underscore the need for a unified connectivity concept. One outstanding need is a way to quantify directional connectivity that is consistent, robust to variations in sampling, and transferable across scales or environmental settings. Understanding connectivity in a particular direction (e.g., streamwise, along or across gradient, between sources and sinks, along cardinal directions) provides critical information for predicting contaminant transport, planning conservation corridor design, and understanding how landscapes or hydroscapes respond to directional forces like wind or water flow. Here we synthesize progress on quantifying connectivity and develop a new strategy for evaluating directional connectivity that benefits from use of graph theory in ecology and percolation theory in hydrology. The directional connectivity index (DCI) is a graph-theory based, multiscale metric that is generalizable to a range of different structural and functional connectivity applications. It exhibits minimal sensitivity to image rotation or resolution within a given range and responds intuitively to progressive, unidirectional change. Further, it is linearly related to the integral connectivity scale length--a metric common in hydrology that correlates well with actual fluxes--but is less computationally challenging and more readily comparable across different landscapes. Connectivity-orientation curves (i.e., directional connectivity computed over a range of headings) provide a quantitative, information-dense representation of environmental structure that can be used for comparison or detection of

  7. The TANF/SSI connection.

    Science.gov (United States)

    Wamhoff, Steve; Wiseman, Michael

    Interactions and overlap of social assistance programs across clients interest policymakers because such interactions affect both the clients' well-being and the programs' efficiency. This article investigates the connections between Supplemental Security Income (SSI) and Temporary Assistance for Needy Families (TANF) and TANF's predecessor, the Aid to Families with Dependent Children (AFDC) program. Connections between receipt of TANF and SSI are widely discussed in both disability policy and poverty research literatures because many families receiving TANF report disabilities. For both states and the individuals involved, it is generally financially advantageous for adults and children with disabilities to transfer from TANF to SSI. States gain because the federal government pays for the SSI benefit, and states can then use the TANF savings for other purposes. The families gain because the SSI benefits they acquire are greater than the TANF benefits they lose. The payoff to states from transferring welfare recipients to SSI was substantially increased when Congress replaced AFDC with TANF in 1996. States retained less than half of any savings achieved through such transfers under AFDC, but they retain all of the savings under TANF. Also, the work participation requirements under TANF have obligated states to address the work support needs of adults with disabilities who remain in TANF, and states can avoid these costs if adults have disabilities that satisfy SSI eligibility requirements. The incentive for TANF recipients to apply for SSI has increased over time as inflation has caused real TANF benefits to fall relative to payments received by SSI recipients. Trends in the financial incentives for transfer to SSI have not been studied in detail, and reliable general data on the extent of the interaction between TANF and SSI are scarce. In addition, some estimates of the prevalence of TANF receipt among SSI awardees are flawed because they fail to include adults

  8. Social media and (dis)connectivity

    DEFF Research Database (Denmark)

    Tække, Jesper

    The paper discuss the relation between media of communication and societal (dis)connectivity. The question is how communication media provide society with different possibilities for (dis)connectivity in different historical media societies. The paper draws on Luhmann’s theory of social systems...... for social systems to develop structures with new forms of communicative connections. Even though society only is possible because of communication media and gets new possibilities for the formation of new structures providing it with new connection possibilities, in the beginning a new communication medium....... In the present society we also see signs of new dis-connectivity, i.e. fake news, political polarization, and economic and democratic inequality. In the final section the paper analyse such problems triggered by digital media. Also the paper point out some new possibilities triggered by the acquisition of social...

  9. Study on the Connecting Length of CFRP

    Science.gov (United States)

    Liu, Xiongfei; Li, Yue; Li, Zhanguo

    2018-05-01

    The paper studied the varying mode of shear stress in the connecting zone of CFRP. Using epoxy resin (EP) as bond material, performance of specimens with different connecting length of CFRP was tested to obtain the conclusion. CFRP-confined concrete column was tested subsequently to verify the conclusion. The results show that: (1) The binding properties of modified epoxy resin with CFRP is good; (2) As the connecting length increased, the ultimate tensile strength of CFRP increased as well in the range of the experiment parameters; (3) Tensile strength of CFRP can reach the ultimate strength when the connecting length is 90mm;(4) The connecting length of 90mm of CFRP meet the reinforcement requirements.

  10. Ecological connectivity networks in rapidly expanding cities.

    Science.gov (United States)

    Nor, Amal Najihah M; Corstanje, Ron; Harris, Jim A; Grafius, Darren R; Siriwardena, Gavin M

    2017-06-01

    Urban expansion increases fragmentation of the landscape. In effect, fragmentation decreases connectivity, causes green space loss and impacts upon the ecology and function of green space. Restoration of the functionality of green space often requires restoring the ecological connectivity of this green space within the city matrix. However, identifying ecological corridors that integrate different structural and functional connectivity of green space remains vague. Assessing connectivity for developing an ecological network by using efficient models is essential to improve these networks under rapid urban expansion. This paper presents a novel methodological approach to assess and model connectivity for the Eurasian tree sparrow ( Passer montanus ) and Yellow-vented bulbul ( Pycnonotus goiavier ) in three cities (Kuala Lumpur, Malaysia; Jakarta, Indonesia and Metro Manila, Philippines). The approach identifies potential priority corridors for ecological connectivity networks. The study combined circuit models, connectivity analysis and least-cost models to identify potential corridors by integrating structure and function of green space patches to provide reliable ecological connectivity network models in the cities. Relevant parameters such as landscape resistance and green space structure (vegetation density, patch size and patch distance) were derived from an expert and literature-based approach based on the preference of bird behaviour. The integrated models allowed the assessment of connectivity for both species using different measures of green space structure revealing the potential corridors and least-cost pathways for both bird species at the patch sites. The implementation of improvements to the identified corridors could increase the connectivity of green space. This study provides examples of how combining models can contribute to the improvement of ecological networks in rapidly expanding cities and demonstrates the usefulness of such models for

  11. Ecological connectivity networks in rapidly expanding cities

    Directory of Open Access Journals (Sweden)

    Amal Najihah M. Nor

    2017-06-01

    Full Text Available Urban expansion increases fragmentation of the landscape. In effect, fragmentation decreases connectivity, causes green space loss and impacts upon the ecology and function of green space. Restoration of the functionality of green space often requires restoring the ecological connectivity of this green space within the city matrix. However, identifying ecological corridors that integrate different structural and functional connectivity of green space remains vague. Assessing connectivity for developing an ecological network by using efficient models is essential to improve these networks under rapid urban expansion. This paper presents a novel methodological approach to assess and model connectivity for the Eurasian tree sparrow (Passer montanus and Yellow-vented bulbul (Pycnonotus goiavier in three cities (Kuala Lumpur, Malaysia; Jakarta, Indonesia and Metro Manila, Philippines. The approach identifies potential priority corridors for ecological connectivity networks. The study combined circuit models, connectivity analysis and least-cost models to identify potential corridors by integrating structure and function of green space patches to provide reliable ecological connectivity network models in the cities. Relevant parameters such as landscape resistance and green space structure (vegetation density, patch size and patch distance were derived from an expert and literature-based approach based on the preference of bird behaviour. The integrated models allowed the assessment of connectivity for both species using different measures of green space structure revealing the potential corridors and least-cost pathways for both bird species at the patch sites. The implementation of improvements to the identified corridors could increase the connectivity of green space. This study provides examples of how combining models can contribute to the improvement of ecological networks in rapidly expanding cities and demonstrates the usefulness of such

  12. Solar line Lsub(α) profile and an interstellar wind dynamics

    International Nuclear Information System (INIS)

    Burgin, M.S.

    1978-01-01

    Analytical theory of interstellar hydrogen atom motion into the region of solar Lsub(α)-radiation is given. Hydrogen distribution in the Solar system is calculated with an account of the Lsub(α) solar line profile difference from a flat one. The effect of the profile form on the scattered radiation intensity is estimated. Calculation errors of the scattered radiation intensity, connected with the difference between a line profile and a flat one, do not exceed 5% for the real Lsub(α) solar line profile

  13. Reliability Assessment of Transformerless PV Inverters considering Mission Profiles

    Directory of Open Access Journals (Sweden)

    Yongheng Yang

    2015-01-01

    Full Text Available Due to the small volume and high efficiency, transformerless inverters have gained much popularity in grid-connected PV applications, where minimizing leakage current injection is mandatory. This can be achieved by either modifying the modulation schemes or adding extra power switching devices, resulting in an uneven distribution of the power losses on the switching devices. Consequently, the device thermal loading is redistributed and thus may alter the entire inverter reliability performance, especially under a long-term operation. In this consideration, this paper assesses the device reliability of three transformerless inverters under a yearly mission profile (i.e., solar irradiance and ambient temperature. The mission profile is translated to device thermal loading, which is used for lifetime prediction. Comparison results reveal the lifetime mismatches among the power switching devices operating under the same condition, which offers new thoughts for a robust design and a reliable operation of grid-connected transformerless PV inverters with high efficiency.

  14. A searchable cross-platform gene expression database reveals connections between drug treatments and disease

    Directory of Open Access Journals (Sweden)

    Williams Gareth

    2012-01-01

    Full Text Available Abstract Background Transcriptional data covering multiple platforms and species is collected and processed into a searchable platform independent expression database (SPIED. SPIED consists of over 100,000 expression fold profiles defined independently of control/treatment assignment and mapped to non-redundant gene lists. The database is thus searchable with query profiles defined over genes alone. The motivation behind SPIED is that transcriptional profiles can be quantitatively compared and ranked and thus serve as effective surrogates for comparing the underlying biological states across multiple experiments. Results Drug perturbation, cancer and neurodegenerative disease derived transcriptional profiles are shown to be effective descriptors of the underlying biology as they return related drugs and pathologies from SPIED. In the case of Alzheimer's disease there is high transcriptional overlap with other neurodegenerative conditions and rodent models of neurodegeneration and nerve injury. Combining the query signature with correlating profiles allows for the definition of a tight neurodegeneration signature that successfully highlights many neuroprotective drugs in the Broad connectivity map. Conclusions Quantitative querying of expression data from across the totality of deposited experiments is an effective way of discovering connections between different biological systems and in particular that between drug action and biological disease state. Examples in cancer and neurodegenerative conditions validate the utility of SPIED.

  15. Grid-connected ICES: preliminary feasibility analysis and evaluation. Volume 3. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-06-30

    Maps, charts, and drawings of the Demonstration Community for the grid-connected ICES project composed of the medical complex in New Orleans (HEAL) are presented in Appendix A. The physical profile of the existing buildings and site plans is included. Demand profiles for steam, electric, gas, etc. are presented in Appendix B with extensive tables and graphs. Air quality and noise pollution data are presented in Appendix C. Data on financing in Appendix D are presented and also texts and information on revenue bonds are given. The final appendix gives qualifications for personnel for HEAL; NOSPI; de Laureal Engineers, Inc.; and Orr-Schelen-Mayeron and Associates, Inc.

  16. Spiking the expectancy profiles

    DEFF Research Database (Denmark)

    Hansen, Niels Chr.; Loui, Psyche; Vuust, Peter

    Melodic expectations have long been quantified using expectedness ratings. Motivated by statistical learning and sharper key profiles in musicians, we model musical learning as a process of reducing the relative entropy between listeners' prior expectancy profiles and probability distributions...... of a given musical style or of stimuli used in short-term experiments. Five previous probe-tone experiments with musicians and non-musicians are revisited. Exp. 1-2 used jazz, classical and hymn melodies. Exp. 3-5 collected ratings before and after exposure to 5, 15 or 400 novel melodies generated from...... a finite-state grammar using the Bohlen-Pierce scale. We find group differences in entropy corresponding to degree and relevance of musical training and within-participant decreases after short-term exposure. Thus, whereas inexperienced listeners make high-entropy predictions by default, statistical...

  17. Profile of success

    DEFF Research Database (Denmark)

    Dahlgaard, Jens Jørn; Nørgaard, Anders; Jakobsen, Søren

    1998-01-01

    What management skills must Europe's business leaders improve to achieve business excellence? Which country's leaders are best placed for success? Does the next generation have what it takes to compete? In the second half of their study of the leadership styles that drive business excellence, Jens...... Dahlgaard, Anders Nørgaard and Søren Jakobsen describe an excellent leadership profile that provides the answers....

  18. Global gas company profiles

    International Nuclear Information System (INIS)

    1997-01-01

    This report provides a detailed assessment of 60 of the top gas companies form around the world, analysing them according to their internal dynamics and in relation to their competitors. It devotes each chapter to an individual company, providing invaluable insight into the organisation's operational background, financial performance and strategic goals. Using the most up-to-date information available, Global Gas Company Profiles allows you to make detailed analysis of each company's performance and future direction. (author)

  19. Controlling magnetic field profiles

    International Nuclear Information System (INIS)

    Freeman, J.R.

    1979-04-01

    A method for designing solenoid magnets with controlled field profiles is discussed. The method, originated by D.B. Montgomery, minimizes both the field errors and the power consumption. An NOS time-sharing computer program for the CDC-6600, entitled MAGCOR, was constructed to provide an interactive magnet design capability. Results obtained during the design of magnets for a radial line electron accelerator are presented. 9 figures

  20. Social network profiles as information sources for adolescents' offline relations

    OpenAIRE

    Courtois, Cédric; All, Anissa; Vanwynsberghe, Hadewijch

    2012-01-01

    This paper presents the results of a study concerning the use of online profile pages by adolescents to know more about “offline” friends and acquaintances. Previous research has indicated that social networking sites (SNSs) are used to gather information on new online contacts. However, several studies have demonstrated a substantial overlap between offline and online social networks. Hence, we question whether online connections are meaningful in gathering information on offline friends and...

  1. Fitting the IRI F2-profile function to measured profiles

    International Nuclear Information System (INIS)

    Reinisch, B.W.; Huang Xueqin

    1997-01-01

    Comparison with profile data from ionosondes shows that the IRI bottomside F2-profiles can be improved by using better B0 and B1 parameters. The best parameters (in a least-squares sense) can be easily calculated in a numerical procedure from measured profiles presented as a sum of Chebyshev polynomials. 7 refs, 5 figs, 1 tab

  2. The role of Long-Range Connectivity for the Characterization of the Functional-Anatomical Organization of the Cortex

    Directory of Open Access Journals (Sweden)

    Thomas R Knösche

    2011-07-01

    Full Text Available This review focuses on the role of long-range connectivity as one element of brain structure that is of key importance for the functional-anatomical organization of the cortex. In this context, we discuss the putative guiding principles for mapping brain function and structure onto the cortical surface. Such mappings reveal a high-degree of functional-anatomical segregation. Given that brain regions frequently maintain characteristic connectivity profiles and the functional repertoire of a cortical area is closely related to its anatomical connections, long-range connectivity may be used to define segregated cortical areas. This methodology is called connectivity-based parcellation.Within this framework, we investigate different techniques to estimate connectivity profiles with emphasis given to non-invasive methods based on diffusion magnetic resonance imaging (dMRI and diffusion tractography. Cortical parcellation is then defined based on similarity between diffusion tractograms, and different clustering approaches are discussed.We conclude that the use of non-invasively acquired connectivity estimates to characterize the functional-anatomical organization of the brain is a valid, relevant and necessary endeavor. Current and future developments in dMRI technology, tractography algorithms and models of the similarity structure hold great potential for a substantial improvement and enrichment of the results of the technique.

  3. The role of long-range connectivity for the characterization of the functional-anatomical organization of the cortex.

    Science.gov (United States)

    Knösche, Thomas R; Tittgemeyer, Marc

    2011-01-01

    This review focuses on the role of long-range connectivity as one element of brain structure that is of key importance for the functional-anatomical organization of the cortex. In this context, we discuss the putative guiding principles for mapping brain function and structure onto the cortical surface. Such mappings reveal a high degree of functional-anatomical segregation. Given that brain regions frequently maintain characteristic connectivity profiles and the functional repertoire of a cortical area is closely related to its anatomical connections, long-range connectivity may be used to define segregated cortical areas. This methodology is called connectivity-based parcellation. Within this framework, we investigate different techniques to estimate connectivity profiles with emphasis given to non-invasive methods based on diffusion magnetic resonance imaging (dMRI) and diffusion tractography. Cortical parcellation is then defined based on similarity between diffusion tractograms, and different clustering approaches are discussed. We conclude that the use of non-invasively acquired connectivity estimates to characterize the functional-anatomical organization of the brain is a valid, relevant, and necessary endeavor. Current and future developments in dMRI technology, tractography algorithms, and models of the similarity structure hold great potential for a substantial improvement and enrichment of the results of the technique.

  4. Abnormal interhemispheric connectivity in male psychopathic offenders.

    Science.gov (United States)

    Hoppenbrouwers, Sylco S; De Jesus, Danilo R; Sun, Yinming; Stirpe, Tania; Hofman, Dennis; McMaster, Jeff; Hughes, Ginny; Daskalakis, Zafiris J; Schutter, Dennis J L G

    2014-01-01

    Psychopathic offenders inevitably violate interpersonal norms and frequently resort to aggressive and criminal behaviour. The affective and cognitive deficits underlying these behaviours have been linked to abnormalities in functional interhemispheric connectivity. However, direct neurophysiological evidence for dysfunctional connectivity in psychopathic offenders is lacking. We used transcranial magnetic stimulation combined with electroencephalography to examine interhemispheric connectivity in the dorsolateral and motor cortex in a sample of psychopathic offenders and healthy controls. We also measured intracortical inhibition and facilitation over the left and right motor cortex to investigate the effects of local cortical processes on interhemispheric connectivity. We enrolled 17 psychopathic offenders and 14 controls in our study. Global abnormalities in right to left functional connectivity were observed in psychopathic offenders compared with controls. Furthermore, in contrast to controls, psychopathic offenders showed increased intracortical inhibition in the right, but not the left, hemisphere. The relatively small sample size limited the sensitivity to show that the abnormalities in interhemispheric connectivity were specifically related to the dorsolateral prefrontal cortex in psychopathic offenders. To our knowledge, this study provides the first neurophysiological evidence for abnormal interhemispheric connectivity in psychopathic offenders and may further our understanding of the disruptive antisocial behaviour of these offenders.

  5. Structural and effective connectivity in focal epilepsy

    Directory of Open Access Journals (Sweden)

    Christopher S. Parker

    2018-01-01

    Full Text Available Patients with medically-refractory focal epilepsy may be candidates for neurosurgery and some may require placement of intracranial EEG electrodes to localise seizure onset. Assessing cerebral responses to single pulse electrical stimulation (SPES may give diagnostically useful data. SPES produces cortico-cortical evoked potentials (CCEPs, which infer effective brain connectivity. Diffusion-weighted images and tractography may be used to estimate structural brain connectivity. This combination provides the opportunity to observe seizure onset and its propagation throughout the brain, spreading contiguously along the cortex explored with electrodes, or non-contiguously. We analysed CCEPs and diffusion tractography in seven focal epilepsy patients and reconstructed the effective and structural brain networks. We aimed to assess the inter-modal similarity of the networks at a large scale across the cortex, the effective and structural connectivity of the ictal-onset zone, and investigate potential mechanisms of non-contiguous seizure spread. We found a significant overlap between structural and effective networks. Effective network CCEP amplitude, baseline variation, and outward connectivity was higher at ictal-onset zones, while structural connection strength within the ictal-onset zone tended to be higher. These findings support the concept of hyperexcitable cortex being associated with seizure generation. The high prevalence of structural and effective connections from the ictal-onset zone to sites of non-contiguous spread suggests that macroscopic structural and effective connections are plausible routes for non-contiguous seizure spread.

  6. Optimising the economic viability of grid-connected photovoltaic systems

    International Nuclear Information System (INIS)

    Mondol, Jayanta Deb; Yohanis, Yigzaw G; Norton, Brian

    2009-01-01

    The impact of photovoltaic (PV) array size, orientation, inclination, load profile, electricity buying price, feed-in tariffs, PV/inverter sizing ratio ('sizing ratio') and PV/inverter cost ratio ('cost ratio') on the economic viability of a grid-connected PV system was investigated using a validated TRNSYS simulation model. The results showed that the fractional load met directly by a PV system depends on matching between PV supply and building load profile, sizing ratio and PV inclination. The profitability of a grid-connected PV system increases if the PV system is sized to reduce excess PV electrical energy fed to the grid when the feed-in tariff is lower than electricity buying price. The effect of feed-in tariffs on PV saving for selected European countries has been shown. The cost of the PV electricity depends on sizing ratio, PV and inverter lifetimes, cost ratio, PV inclination and financial parameters. The effect of cost ratio on the optimum PV/inverter sizing ratio is less significant when the cost ratio lies within 7-11. The minimum PV electricity cost at low and high insolation conditions were obtained for sizing ratios of 1.6 and 1.2, respectively. The lowest PV electricity cost was found for surface slopes within 30-40 for the selected European locations. The PV electricity cost for cost ratio of 5 and 13 varied from 0.44-0.85 EURkWh -1 to 0.38-0.76 EURkWh -1 , respectively within high to low insolation conditions when the PV module unit cost, market discount rate, PV size, PV lifetime and inverter lifetime were assumed to be 6.5 EURW p -1 , 3%, 13 kW p , 20 years and 10 years, respectively. (author)

  7. Connecting Secondary Career and Technical Education and Registered Apprenticeship: A Profile of Six State Systems

    Science.gov (United States)

    Rice, Olivia; Hudson, Jordan; Foster, Laura Rasmussen; Klein, Steven

    2016-01-01

    Work-based learning, an educational strategy that provides students with technical skills and knowledge in an authentic work setting, is often delivered through a Career Technical Education (CTE) or Registered Apprenticeship (RA) program. Both have overlapping structures and content, including experiential learning and career exploration…

  8. Altered thalamic functional connectivity in multiple sclerosis

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yaou; Liang, Peipeng; Duan, Yunyun; Huang, Jing; Ren, Zhuoqiong; Jia, Xiuqin [Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053 (China); Dong, Huiqing; Ye, Jing [Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053 (China); Shi, Fu-Dong [Department of Neurology and Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052 (China); Butzkueven, Helmut [Department of Medicine, University of Melbourne, Parkville 3010 (Australia); Li, Kuncheng, E-mail: kunchengli55@gmail.com [Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053 (China)

    2015-04-15

    Highlights: •We demonstrated decreased connectivity between thalamus and cortical regions in MS. •Increased intra- and inter-thalamic connectivity was also observed in MS. •The increased functional connectivity is attenuated by increasing disease duration. -- Abstract: Objective: To compare thalamic functional connectivity (FC) in patients with multiple sclerosis (MS) and healthy controls (HC), and correlate these connectivity measures with other MRI and clinical variables. Methods: We employed resting-state functional MRI (fMRI) to examine changes in thalamic connectivity by comparing thirty-five patients with MS and 35 age- and sex-matched HC. Thalamic FC was investigated by correlating low frequency fMRI signal fluctuations in thalamic voxels with voxels in all other brain regions. Additionally thalamic volume fraction (TF), T2 lesion volume (T2LV), EDSS and disease duration were recorded and correlated with the FC changes. Results: MS patients were found to have a significantly lower TF than HC in bilateral thalami. Compared to HC, the MS group showed significantly decreased FC between thalamus and several brain regions including right middle frontal and parahippocampal gyri, and the left inferior parietal lobule. Increased intra- and inter-thalamic FC was observed in the MS group compared to HC. These FC alterations were not correlated with T2LV, thalamic volume or lesions. In the MS group, however, there was a negative correlation between disease duration and inter-thalamic connectivity (r = −0.59, p < 0.001). Conclusion: We demonstrated decreased FC between thalamus and several cortical regions, while increased intra- and inter-thalamic connectivity in MS patients. These complex functional changes reflect impairments and/or adaptations that are independent of T2LV, thalamic volume or presence of thalamic lesions. The negative correlation between disease duration and inter-thalamic connectivity could indicate an adaptive role of thalamus that is

  9. Depression: a psychiatric nursing theory of connectivity.

    Science.gov (United States)

    Feely, M; Long, A

    2009-10-01

    This paper presents a theory of connectivity, which was formulated from the findings of a Classical Grounded Theory study that was designed to capture a sample of people's perceptions of living with depression or caring for individuals with depression. Data were collected from: (1) a focus group consisting of people with depression (n = 7), of which five were patients in the community and two were nurses; (2) one-to-one interviews with patients in the community (n = 5) and nurses (n = 5), three of whom had experienced depression from both sides of the caring process; and (3) two 'happy accident' focus groups (n = 25; n = 18) comprising of healthcare workers with a shared understanding of depression. Purposeful sampling was used initially. Thereafter, in keeping with one of the key tenets of grounded theory, theoretical sampling was used until theoretical saturation occurred. Data were analysed using the constant comparative approach together with the NVivo qualitative analysis software package. The core category that emerged was 'connectivity' relating to the connections and disconnections, which people make in their lives. Six key categories emerged all of which were integrated with the core category. Hence, connectivity provided a significant platform for understanding and responding to the life experience of depression. They were: (1) life encounters on the journey to naming; (2) depression: What's in a name? The silent thief; (3) tentative steps to health care; (4) connective encounters and challenges; (5) connecting with self; and (6) self-connection maintenance. Subsequently, a theory, 'Depression: a psychiatric nursing theory of connectivity', surfaced from the overall findings. We argue that this theory of connectivity provides a framework that people working in the field of holistic treatment and care could use to better understand and respond to the life experience of people living with depression.

  10. Detecting Functional Connectivity During Audiovisual Integration with MEG: A Comparison of Connectivity Metrics.

    Science.gov (United States)

    Ard, Tyler; Carver, Frederick W; Holroyd, Tom; Horwitz, Barry; Coppola, Richard

    2015-08-01

    In typical magnetoencephalography and/or electroencephalography functional connectivity analysis, researchers select one of several methods that measure a relationship between regions to determine connectivity, such as coherence, power correlations, and others. However, it is largely unknown if some are more suited than others for various types of investigations. In this study, the authors investigate seven connectivity metrics to evaluate which, if any, are sensitive to audiovisual integration by contrasting connectivity when tracking an audiovisual object versus connectivity when tracking a visual object uncorrelated with the auditory stimulus. The authors are able to assess the metrics' performances at detecting audiovisual integration by investigating connectivity between auditory and visual areas. Critically, the authors perform their investigation on a whole-cortex all-to-all mapping, avoiding confounds introduced in seed selection. The authors find that amplitude-based connectivity measures in the beta band detect strong connections between visual and auditory areas during audiovisual integration, specifically between V4/V5 and auditory cortices in the right hemisphere. Conversely, phase-based connectivity measures in the beta band as well as phase and power measures in alpha, gamma, and theta do not show connectivity between audiovisual areas. The authors postulate that while beta power correlations detect audiovisual integration in the current experimental context, it may not always be the best measure to detect connectivity. Instead, it is likely that the brain utilizes a variety of mechanisms in neuronal communication that may produce differential types of temporal relationships.

  11. Natural current profiles in tokamaks

    International Nuclear Information System (INIS)

    Biskamp, D.

    1986-01-01

    It is proposed that a certain class of equilibrium, which follow from an elementary variational principle, are the natural current profiles in tokamaks, to which actual discharge profiles tend to relax. (orig.)

  12. GHGRP Minerals Sector Industrial Profile

    Science.gov (United States)

    EPA's Greenhouse Gas Reporting Program periodically produces detailed profiles of the various industries that report under the program. The profiles available for download below contain detailed analyses for the Minerals industry.

  13. Are people more connective than political actions?

    DEFF Research Database (Denmark)

    Shehata, Mostafa

    2017-01-01

    The recent wave of Internet-based social movements in the Arab Spring countries and elsewhere has considerably changed the organizational structure of contentious action. One of the current and most significant theories that has handled this change is the logic of connective action, which...... distinguishes between two major types of contentious action: collective and connective. In the context of this theory, this article puts forward a new conception of political action participants and attempts to classify them along the categories of collective or connective. This conception, which consists...

  14. Reliability Oriented Design Tool For the New Generation of Grid Connected PV-Inverters

    DEFF Research Database (Denmark)

    Sintamarean, Nicolae Cristian; Blaabjerg, Frede; Wang, Huai

    2015-01-01

    is achieved and is further used as an input to the lifetime model. The proposed reliability-oriented design tool is used to study the impact of mission profile (MP) variation and device degradation (aging) in the PV inverter lifetime. The obtained results indicate that the MP of the field where the PV...... inverter is operating has an important impact (up to 70%) on the converter lifetime expectation, and it should be considered in the design stage to better optimize the converter design margin. In order to have correct lifetime estimation, it is crucial to consider also the device degradation feedback (in......This paper introduces a reliability-oriented design tool for a new generation of grid-connected photovoltaic (PV) inverters. The proposed design tool consists of a real field mission profile (RFMP) model (for two operating regions: USA and Denmark), a PV panel model, a grid-connected PV inverter...

  15. Synthesis of national risk profile

    Science.gov (United States)

    1979-01-01

    The methodology used and results obtained in computing the national risk profile for carbon fibers (CF) released after an aircraft accident (fire or explosion) are presented. The computation was performed by use of twenty-six individual conditional risk profiles, together with the extrapolation of these profiles to other U.S. airports. The risk profile was obtained using 1993 CF utilization forecasts, but numbers of facilities were taken from 1972 and 1975 census data, while losses were expressed in 1977 dollars.

  16. Do storage dynamics in hydropedological units control hydrological connectivity? (Invited)

    Science.gov (United States)

    Tetzlaff, D.; Birkel, C.; Dick, J.; Geris, J.; Soulsby, C.

    2013-12-01

    In many northern landscapes, peat-dominated riparian wetlands often characterise the zone of connection between terrestrial drainage and the river network. In order to understand the relationship between connectivity and stream flow generation in a montane headwater catchment, we examined the storage dynamics and isotopic composition of soil water in major hydropedological units. These formed a classic catena sequence for northern catchments from free-draining podzols on steep upper hillslopes through to peaty gleysols in lower receiving slopes to deeper peats (Histosols) in the riparian zone. The peaty gleys and peats remained saturated throughout the year, whilst the podzols showed distinct wetting and drying cycles. In this climatic region, most precipitation events are less than 10mm in magnitude, storm runoff is mainly generated from the Histosols and Gleysols, with runoff coefficients (RCs) typically horizons of the soils due to mixing with larger volumes of stored water. This damping is accentuated in the deeper soil profile and groundwater. Consequently, the isotopic composition of stream water is also damped, but the strongly reflects that of the near surface waters in the riparian peats. Old 'pre-event' water generally accounts for >80% of flow, even in large events, mainly reflecting the displacement of water stored in the riparian peats and peaty gleys. These riparian areas appear to be the dominant zone where different catchment source waters mix; acting as an 'isostat' that regulates the isotopic composition of stream waters and integrates the Transit Time Distribution (TTD) for the catchment.

  17. Never forget a name: white matter connectivity predicts person memory

    Science.gov (United States)

    Metoki, Athanasia; Alm, Kylie H.; Wang, Yin; Ngo, Chi T.; Olson, Ingrid R.

    2018-01-01

    Through learning and practice, we can acquire numerous skills, ranging from the simple (whistling) to the complex (memorizing operettas in a foreign language). It has been proposed that complex learning requires a network of brain regions that interact with one another via white matter pathways. One candidate white matter pathway, the uncinate fasciculus (UF), has exhibited mixed results for this hypothesis: some studies have shown UF involvement across a range of memory tasks, while other studies report null results. Here, we tested the hypothesis that the UF supports associative memory processes and that this tract can be parcellated into subtracts that support specific types of memory. Healthy young adults performed behavioral tasks (two face-name learning tasks, one word pair memory task) and underwent a diffusion-weighted imaging scan. Our results revealed that variation in UF microstructure was significantly associated with individual differences in performance on both face-name tasks, as well as the word association memory task. A UF sub-tract, functionally defined by its connectivity between face-selective regions in the anterior temporal lobe and orbitofrontal cortex, selectively predicted face-name learning. In contrast, connectivity between the fusiform face patch and both anterior face patches had no predictive validity. These findings suggest that there is a robust and replicable relationship between the UF and associative learning and memory. Moreover, this large white matter pathway can be subdivided to reveal discrete functional profiles. PMID:28646241

  18. Real field mission profile oriented design of a SiC-based PV-inverter application

    DEFF Research Database (Denmark)

    Sintamarean, Nicolae Christian; Blaabjerg, Frede; Wang, Huai

    2013-01-01

    This paper introduces a real field mission profile oriented design tool for the new generation of grid connected PV-inverters applications based on SiC-devices. The proposed design tool consists of a grid connected PV-inverter model, an ElectroThermal model, a converter safe operating area (SOA...... Zth_H in order to perform in a safe mode for the whole operating range. Furthermore, the proposed design tool considers the mission profile (the measured solar irradiance and ambient temperature) from the real field where the converter will operate. Thus, a realistic loading of the converter devices......) model, a mission profile model and an the evaluation block. The PV-system model involves a three level bipolar switch neutral point clamped (3L-BS NPC) inverter connected to the three phase grid through a LCL-filter. Moreover, the SOA model calculates the required converter heatsink thermal impedance...

  19. Evaluation of phenoxybenzamine in the CFA model of pain following gene expression studies and connectivity mapping.

    Science.gov (United States)

    Chang, Meiping; Smith, Sarah; Thorpe, Andrew; Barratt, Michael J; Karim, Farzana

    2010-09-16

    We have previously used the rat 4 day Complete Freund's Adjuvant (CFA) model to screen compounds with potential to reduce osteoarthritic pain. The aim of this study was to identify genes altered in this model of osteoarthritic pain and use this information to infer analgesic potential of compounds based on their own gene expression profiles using the Connectivity Map approach. Using microarrays, we identified differentially expressed genes in L4 and L5 dorsal root ganglia (DRG) from rats that had received intraplantar CFA for 4 days compared to matched, untreated control animals. Analysis of these data indicated that the two groups were distinguishable by differences in genes important in immune responses, nerve growth and regeneration. This list of differentially expressed genes defined a "CFA signature". We used the Connectivity Map approach to identify pharmacologic agents in the Broad Institute Build02 database that had gene expression signatures that were inversely related ('negatively connected') with our CFA signature. To test the predictive nature of the Connectivity Map methodology, we tested phenoxybenzamine (an alpha adrenergic receptor antagonist) - one of the most negatively connected compounds identified in this database - for analgesic activity in the CFA model. Our results indicate that at 10 mg/kg, phenoxybenzamine demonstrated analgesia comparable to that of Naproxen in this model. Evaluation of phenoxybenzamine-induced analgesia in the current study lends support to the utility of the Connectivity Map approach for identifying compounds with analgesic properties in the CFA model.

  20. Connection factor calculation for isotopic neutron flux measurements with foil detectors

    International Nuclear Information System (INIS)

    Avila L, J.

    1987-01-01

    Thermal and resonance neutron self-shielding factors, neutron flux distortion and edge effects as well as a connection factor for neutron flux profile around a foil detector have been calculated. A general expression for resonance self shielding factor is presented in order to take into account the most important resonances for a given isotope. A computer program SPRESYTER.BAS was written and results for In-115 and Au-197 foils are given

  1. Transit signal priority with connected vehicle technology.

    Science.gov (United States)

    2014-01-01

    A new TSP logic was proposed, taking advantage of the resources provided by Connected Vehicle (CV) : technology, including two-way communication between the bus and the traffic signal controller, accurate bus : location detection and prediction, and ...

  2. Connected Vehicle Technologies for Efficient Urban Transportation

    Science.gov (United States)

    2016-10-24

    Connected vehicle technology is employed to optimize the vehicle's control system in real-time to reduce congestion, improve fuel economy, and reduce emissions. This project's goal was to develop a two-way communication system to upload vehicle data ...

  3. PROCESS OF ELECTRICAL CONNECTION OF PHOTOVOLTAIC DEVICES

    DEFF Research Database (Denmark)

    2012-01-01

    A photovoltaic cell module comprising at least two serially connected photovoltaic cells on a common substrate, wherein the cells each comprise a first electrode layer, a first charge selective layer, a light harvesting layer which comprises an organic conjugated polymer, and a second charge...... of the pair, which connection is made through the light harvesting layer common to the at least one pair of cells, without forming an electrical connection with the first electrode of the first cell or the second charge selective layer of the second cell; and a method of making such a photovoltaic cell module....... selective layer is formed such that the second charge selective layer of one cell has no direct electrical connection to the second charge selective layer of any other cell, and wherein the light-harvesting layer is formed such that it is common to at least one pair of adjacent cells of the module; wherein...

  4. Low-stress bicycling and network connectivity.

    Science.gov (United States)

    2012-05-01

    For a bicycling network to attract the widest possible segment of the population, its most fundamental attribute should be low-stress connectivity, that is, providing routes between peoples origins and destinations that do not require cyclists to ...

  5. Switch-connected HyperX network

    Science.gov (United States)

    Chen, Dong; Heidelberger, Philip

    2018-02-13

    A network system includes a plurality of sub-network planes and global switches. The sub-network planes have a same network topology as each other. Each of the sub-network planes includes edge switches. Each of the edge switches has N ports. Each of the global switches is configured to connect a group of edge switches at a same location in the sub-network planes. In each of the sub-network planes, some of the N ports of each of the edge switches are connected to end nodes, and others of the N ports are connected to other edge switches in the same sub-network plane, other of the N ports are connected to at least one of the global switches.

  6. The Listening Train: A Collaborative, Connective Aesthetics ...

    African Journals Online (AJOL)

    The Listening Train: A Collaborative, Connective Aesthetics Approach to Transgressive Social Learning. ... Southern African Journal of Environmental Education. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue ...

  7. Transistor Effect in Improperly Connected Transistors.

    Science.gov (United States)

    Luzader, Stephen; Sanchez-Velasco, Eduardo

    1996-01-01

    Discusses the differences between the standard representation and a realistic representation of a transistor. Presents an experiment that helps clarify the explanation of the transistor effect and shows why transistors should be connected properly. (JRH)

  8. Connecting Vietnam's isolated communities to improve healthcare ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2018-01-29

    Jan 29, 2018 ... Connecting Vietnam's isolated communities to improve healthcare ... of pregnancy and new motherhood improved their interactions with health workers. ... Return to main page: Overcoming eHealth challenges with social and ...

  9. EMPOWERING GIRLS AND CONNECTING PEOPLE THROUGH ...

    African Journals Online (AJOL)

    Mugumbate

    through a school social work intervention and connecting the people who will support the ... best legacy we can bequeath children has been an old .... Some 14 million women and girls between ages 15 and ... Harmful traditional practices.

  10. Feedwater connection repair and modification at GKN

    Energy Technology Data Exchange (ETDEWEB)

    Witteman, C; Klees, J E

    1985-03-01

    From January to March 1983 the feedwater connection of GKN was repaired using a boring lathe, spark machining and semi-automatic welding. Nondestructive examination was performed by ultrasonic and eddy-current testing.

  11. Automated and connected vehicle implications and analysis.

    Science.gov (United States)

    2017-05-01

    Automated and connected vehicles (ACV) and, in particular, autonomous vehicles have captured : the interest of the public, industry and transportation authorities. ACVs can significantly reduce : accidents, fuel consumption, pollution and the costs o...

  12. Feedwater connection repair and modification at GKN

    International Nuclear Information System (INIS)

    Witteman, C.; Klees, J.E.

    1985-01-01

    From Jan. to March 1983 the feedwater connection of GKN was repaired using a boring lathe, spark machining and semi-automatic welding. Nondestructive examination was performed by ultrasonic and eddy-current testing

  13. Asthma Research: The NIH–NJRC Connection

    Science.gov (United States)

    ... Bar Home Current Issue Past Issues Special Section Asthma Research: The NIH–NJRC Connection Past Issues / Fall ... the many ways that NIH supports and promotes asthma research is through its strong relationship with National ...

  14. Periodic words connected with the Fibonacci words

    Directory of Open Access Journals (Sweden)

    G. M. Barabash

    2016-06-01

    Full Text Available In this paper we introduce two families of periodic words (FLP-words of type 1 and FLP-words of type 2 that are connected with the Fibonacci words and investigated their properties.

  15. Better models are more effectively connected models

    Science.gov (United States)

    Nunes, João Pedro; Bielders, Charles; Darboux, Frederic; Fiener, Peter; Finger, David; Turnbull-Lloyd, Laura; Wainwright, John

    2016-04-01

    The concept of hydrologic and geomorphologic connectivity describes the processes and pathways which link sources (e.g. rainfall, snow and ice melt, springs, eroded areas and barren lands) to accumulation areas (e.g. foot slopes, streams, aquifers, reservoirs), and the spatial variations thereof. There are many examples of hydrological and sediment connectivity on a watershed scale; in consequence, a process-based understanding of connectivity is crucial to help managers understand their systems and adopt adequate measures for flood prevention, pollution mitigation and soil protection, among others. Modelling is often used as a tool to understand and predict fluxes within a catchment by complementing observations with model results. Catchment models should therefore be able to reproduce the linkages, and thus the connectivity of water and sediment fluxes within the systems under simulation. In modelling, a high level of spatial and temporal detail is desirable to ensure taking into account a maximum number of components, which then enables connectivity to emerge from the simulated structures and functions. However, computational constraints and, in many cases, lack of data prevent the representation of all relevant processes and spatial/temporal variability in most models. In most cases, therefore, the level of detail selected for modelling is too coarse to represent the system in a way in which connectivity can emerge; a problem which can be circumvented by representing fine-scale structures and processes within coarser scale models using a variety of approaches. This poster focuses on the results of ongoing discussions on modelling connectivity held during several workshops within COST Action Connecteur. It assesses the current state of the art of incorporating the concept of connectivity in hydrological and sediment models, as well as the attitudes of modellers towards this issue. The discussion will focus on the different approaches through which connectivity

  16. Enumeration of connected Catalan objects by type

    OpenAIRE

    Rhoades, Brendon

    2010-01-01

    Noncrossing set partitions, nonnesting set partitions, Dyck paths, and rooted plane trees are four classes of Catalan objects which carry a notion of type. There exists a product formula which enumerates these objects according to type. We define a notion of `connectivity' for these objects and prove an analogous product formula which counts connected objects by type. Our proof of this product formula is combinatorial and bijective. We extend this to a product formula which counts objects wit...

  17. Meromorphic connections on vector bundles over curves

    Indian Academy of Sciences (India)

    The constant function 1 on X will be denoted by 1X. Note that D(1X) is a logarithmic connection on E whose singular locus is contained in . Conversely, if D is a logarithmic connection on E whose singular locus is contained in , then sending. 1X to D we construct an OX-linear homomorphism D : OX −→ At (E) such that.

  18. CELLULAR CONTROL OF CONNECTIVE TISSUE MATRIX TENSION†

    OpenAIRE

    Langevin, Helene M.; Nedergaard, Maiken; Howe, Alan

    2013-01-01

    The biomechanical behavior of connective tissue in response to stretching is generally attributed to the molecular composition and organization of its extracellular matrix. It also is becoming apparent that fibroblasts play an active role in regulating connective tissue tension. In response to static stretching of the tissue, fibroblasts expand within minutes by actively remodeling their cytoskeleton. This dynamic change in fibroblast shape contributes to the drop in tissue tension that occur...

  19. Functional connectivity change as shared signal dynamics

    Science.gov (United States)

    Cole, Michael W.; Yang, Genevieve J.; Murray, John D.; Repovš, Grega; Anticevic, Alan

    2015-01-01

    Background An increasing number of neuroscientific studies gain insights by focusing on differences in functional connectivity – between groups, individuals, temporal windows, or task conditions. We found using simulations that additional insights into such differences can be gained by forgoing variance normalization, a procedure used by most functional connectivity measures. Simulations indicated that these functional connectivity measures are sensitive to increases in independent fluctuations (unshared signal) in time series, consistently reducing functional connectivity estimates (e.g., correlations) even though such changes are unrelated to corresponding fluctuations (shared signal) between those time series. This is inconsistent with the common notion of functional connectivity as the amount of inter-region interaction. New Method Simulations revealed that a version of correlation without variance normalization – covariance – was able to isolate differences in shared signal, increasing interpretability of observed functional connectivity change. Simulations also revealed cases problematic for non-normalized methods, leading to a “covariance conjunction” method combining the benefits of both normalized and non-normalized approaches. Results We found that covariance and covariance conjunction methods can detect functional connectivity changes across a variety of tasks and rest in both clinical and non-clinical functional MRI datasets. Comparison with Existing Method(s) We verified using a variety of tasks and rest in both clinical and non-clinical functional MRI datasets that it matters in practice whether correlation, covariance, or covariance conjunction methods are used. Conclusions These results demonstrate the practical and theoretical utility of isolating changes in shared signal, improving the ability to interpret observed functional connectivity change. PMID:26642966

  20. Hypersurfaces in simply connected space forms

    Indian Academy of Sciences (India)

    Let M be a hypersurface of (M(κ), ds2). For every point m ∈ M, let A: TmM → TmM be the Weingarten map of the hypersurface. In this paper we prove the following results. Theorem 1. Let M be a connected hypersurface in the simply connected space form. (M(κ), ds2) such that the Ricci curvature of M satisfies the inequality ...

  1. Connections between radiation and positronium chemistry

    International Nuclear Information System (INIS)

    Hirade, Tetsuya

    2007-01-01

    Some of the important connections between radiation chemistry and positronium chemistry started from the establishment of the spur reaction model proposed by Mogensen. Now, the modified model, the blob model proposed by Stepanov and Byakov, is making it possible to have the quantitative or semi-quantitative view of the positronium formation by using the distributions of positrons and excess electrons. Some of the interesting topics will be picked up here to understand the connections between radiation chemistry and positronium chemistry

  2. Altered intrinsic and extrinsic connectivity in schizophrenia.

    Science.gov (United States)

    Zhou, Yuan; Zeidman, Peter; Wu, Shihao; Razi, Adeel; Chen, Cheng; Yang, Liuqing; Zou, Jilin; Wang, Gaohua; Wang, Huiling; Friston, Karl J

    2018-01-01

    Schizophrenia is a disorder characterized by functional dysconnectivity among distributed brain regions. However, it is unclear how causal influences among large-scale brain networks are disrupted in schizophrenia. In this study, we used dynamic causal modeling (DCM) to assess the hypothesis that there is aberrant directed (effective) connectivity within and between three key large-scale brain networks (the dorsal attention network, the salience network and the default mode network) in schizophrenia during a working memory task. Functional MRI data during an n-back task from 40 patients with schizophrenia and 62 healthy controls were analyzed. Using hierarchical modeling of between-subject effects in DCM with Parametric Empirical Bayes, we found that intrinsic (within-region) and extrinsic (between-region) effective connectivity involving prefrontal regions were abnormal in schizophrenia. Specifically, in patients (i) inhibitory self-connections in prefrontal regions of the dorsal attention network were decreased across task conditions; (ii) extrinsic connectivity between regions of the default mode network was increased; specifically, from posterior cingulate cortex to the medial prefrontal cortex; (iii) between-network extrinsic connections involving the prefrontal cortex were altered; (iv) connections within networks and between networks were correlated with the severity of clinical symptoms and impaired cognition beyond working memory. In short, this study revealed the predominance of reduced synaptic efficacy of prefrontal efferents and afferents in the pathophysiology of schizophrenia.

  3. Empirical validation of directed functional connectivity.

    Science.gov (United States)

    Mill, Ravi D; Bagic, Anto; Bostan, Andreea; Schneider, Walter; Cole, Michael W

    2017-02-01

    Mapping directions of influence in the human brain connectome represents the next phase in understanding its functional architecture. However, a host of methodological uncertainties have impeded the application of directed connectivity methods, which have primarily been validated via "ground truth" connectivity patterns embedded in simulated functional MRI (fMRI) and magneto-/electro-encephalography (MEG/EEG) datasets. Such simulations rely on many generative assumptions, and we hence utilized a different strategy involving empirical data in which a ground truth directed connectivity pattern could be anticipated with confidence. Specifically, we exploited the established "sensory reactivation" effect in episodic memory, in which retrieval of sensory information reactivates regions involved in perceiving that sensory modality. Subjects performed a paired associate task in separate fMRI and MEG sessions, in which a ground truth reversal in directed connectivity between auditory and visual sensory regions was instantiated across task conditions. This directed connectivity reversal was successfully recovered across different algorithms, including Granger causality and Bayes network (IMAGES) approaches, and across fMRI ("raw" and deconvolved) and source-modeled MEG. These results extend simulation studies of directed connectivity, and offer practical guidelines for the use of such methods in clarifying causal mechanisms of neural processing. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Why have connection costs soared so dramatically?

    International Nuclear Information System (INIS)

    Bahjejian, L.

    2012-01-01

    Thousands of small photovoltaic power stations are demanding their connection to the national power grid. ERDF, the manager of the grid, has to adapt and reinforce some lines. The connection costs that were previously supported by the consumers has to be paid by the demander as the law NOME stipulates it. For installations below 18 kVA the cost ranges from 800 to 1600 euros and for more powerful installations an estimate has to be drawn by ERDF and the cost will depends on the presence or not of an adequate transformer in the vicinity, on the possible upgrading of the transformer, on the length of the cables necessary to make the connection and on whether the installation is in an urban area or not. A table gives the ERDF tariffs for the connection and the case of the connection of a 35 kVA station built on the roof of a shed in a rural zone is dealt with. The procedure to follow for demanding the connection to ERDF is detailed. (A.C.)

  5. Network structure shapes spontaneous functional connectivity dynamics.

    Science.gov (United States)

    Shen, Kelly; Hutchison, R Matthew; Bezgin, Gleb; Everling, Stefan; McIntosh, Anthony R

    2015-04-08

    The structural organization of the brain constrains the range of interactions between different regions and shapes ongoing information processing. Therefore, it is expected that large-scale dynamic functional connectivity (FC) patterns, a surrogate measure of coordination between brain regions, will be closely tied to the fiber pathways that form the underlying structural network. Here, we empirically examined the influence of network structure on FC dynamics by comparing resting-state FC (rsFC) obtained using BOLD-fMRI in macaques (Macaca fascicularis) to structural connectivity derived from macaque axonal tract tracing studies. Consistent with predictions from simulation studies, the correspondence between rsFC and structural connectivity increased as the sample duration increased. Regions with reciprocal structural connections showed the most stable rsFC across time. The data suggest that the transient nature of FC is in part dependent on direct underlying structural connections, but also that dynamic coordination can occur via polysynaptic pathways. Temporal stability was found to be dependent on structural topology, with functional connections within the rich-club core exhibiting the greatest stability over time. We discuss these findings in light of highly variable functional hubs. The results further elucidate how large-scale dynamic functional coordination exists within a fixed structural architecture. Copyright © 2015 the authors 0270-6474/15/355579-10$15.00/0.

  6. Wireless device connection problems and design solutions

    Science.gov (United States)

    Song, Ji-Won; Norman, Donald; Nam, Tek-Jin; Qin, Shengfeng

    2016-09-01

    Users, especially the non-expert users, commonly experience problems when connecting multiple devices with interoperability. While studies on multiple device connections are mostly concentrated on spontaneous device association techniques with a focus on security aspects, the research on user interaction for device connection is still limited. More research into understanding people is needed for designers to devise usable techniques. This research applies the Research-through-Design method and studies the non-expert users' interactions in establishing wireless connections between devices. The "Learning from Examples" concept is adopted to develop a study focus line by learning from the expert users' interaction with devices. This focus line is then used for guiding researchers to explore the non-expert users' difficulties at each stage of the focus line. Finally, the Research-through-Design approach is used to understand the users' difficulties, gain insights to design problems and suggest usable solutions. When connecting a device, the user is required to manage not only the device's functionality but also the interaction between devices. Based on learning from failures, an important insight is found that the existing design approach to improve single-device interaction issues, such as improvements to graphical user interfaces or computer guidance, cannot help users to handle problems between multiple devices. This study finally proposes a desirable user-device interaction in which images of two devices function together with a system image to provide the user with feedback on the status of the connection, which allows them to infer any required actions.

  7. Objective measurement of inhaler inhalation flow profile using acoustic methods

    Energy Technology Data Exchange (ETDEWEB)

    Lacalle, H.; Taylor, T.E.; Marco, S.; Reilly, R.B.

    2016-07-01

    Patients with asthma and chronic obstructive pulmonary diseases (COPD) are mostly treated with inhalers that deliver medication directly to their airways. Drug delivery from dry powder inhalers (DPIs) is very much reliant on the inhalation manoeuvre, specifically the peak inspiratory flow rate (PIFR), inspiratory capacity (IC) and inhalation rise time (IRT) of the inhalation. It has been widely reported that patients may not follow correct inhalation technique while using their inhaler. In this study, a novel acoustic method is proposed to accurately estimate inhalation flow profile using only one inhalation recording for calibration. An Ellipta DPI was placed inside an airtight container with a spirometer connected in order to measure inhalation flow parameters. An acoustic recording device (Inhaler Compliance Assessment (INCA)) was also attached to the DPI. Inhalation audio and flow signals were recorded simultaneously. The data were collected from 20 healthy subjects while performing inhaler inhalations at a range of inspiratory flow rates. A power law regression model was computed to obtain the relationship between the acoustic envelope of the inhalation and flow profile of each recording. Each model was tested on the remaining audio signals to estimate flow profile. The average estimation error was found to be 10.5±0.3% for estimating flow profile from audio signals. Inhalation flow profile parameters (PIFR, IC and IRT) could then be measured from the estimated flow profile with high accuracy giving information on user inhalation technique. This method may assist in improving patient inhaler adherence and overall disease control. (Author)

  8. The effect of geometric scattering on the oscillatory magnetoconductance in multiply connected disordered mesoscopic rings

    International Nuclear Information System (INIS)

    Basu, C.; Gu Benyuan.

    1994-12-01

    We present the quantum mechanical calculations on the conductance of a quantum waveguide consisting of multiply connected mesoscopic rings with disordered ring-circumferences and ballistic lead connections between the rings with the transfer matrix approach. The profiles of the conductance as functions of the magnetic flux and the Fermi wave number of electrons depend on the number of rings as also on the geometric configuration of the system. The conductance spectrum of this system for disordered ring circumferences, disordered ring intervals and disordered magnetic flux is examined in detail. Studying the effect of geometric scattering and the two different length scales involved in the network, namely, the ring circumference and the ballistic lead connections on the conductance profile, we find that there exist two kinds of mini-bands, one originating from the bound states of the rings, i.e. the intrinsic mini-bands, and the other associated with the connecting leads between the adjacent rings, which are the extra mini-bands. These two kinds of mini-bands respond differently to external perturbations in parameters. Unlike the system of potential scatterers, this system of geometric scatterers show complete band formations at all energies even for finite systems and there is a preferential decay of the energy states depending upon the type of disorder introduced. The conductance band structures strongly depend on the geometric configuration of the network and so by controlling the geometric parameters, the conductance band structures can be artificially tailored. (author). 18 refs, 6 figs

  9. Disruption of functional networks in dyslexia: A whole-brain, data-driven analysis of connectivity

    Science.gov (United States)

    Finn, Emily S.; Shen, Xilin; Holahan, John M.; Scheinost, Dustin; Lacadie, Cheryl; Papademetris, Xenophon; Shaywitz, Sally E.; Shaywitz, Bennett A.; Constable, R. Todd

    2013-01-01

    Background Functional connectivity analyses of fMRI data are a powerful tool for characterizing brain networks and how they are disrupted in neural disorders. However, many such analyses examine only one or a small number of a priori seed regions. Studies that consider the whole brain frequently rely on anatomic atlases to define network nodes, which may result in mixing distinct activation timecourses within a single node. Here, we improve upon previous methods by using a data-driven brain parcellation to compare connectivity profiles of dyslexic (DYS) versus non-impaired (NI) readers in the first whole-brain functional connectivity analysis of dyslexia. Methods Whole-brain connectivity was assessed in children (n = 75; 43 NI, 32 DYS) and adult (n = 104; 64 NI, 40 DYS) readers. Results Compared to NI readers, DYS readers showed divergent connectivity within the visual pathway and between visual association areas and prefrontal attention areas; increased right-hemisphere connectivity; reduced connectivity in the visual word-form area (part of the left fusiform gyrus specialized for printed words); and persistent connectivity to anterior language regions around the inferior frontal gyrus. Conclusions Together, findings suggest that NI readers are better able to integrate visual information and modulate their attention to visual stimuli, allowing them to recognize words based on their visual properties, while DYS readers recruit altered reading circuits and rely on laborious phonology-based “sounding out” strategies into adulthood. These results deepen our understanding of the neural basis of dyslexia and highlight the importance of synchrony between diverse brain regions for successful reading. PMID:24124929

  10. Deflagration Wave Profiles

    Energy Technology Data Exchange (ETDEWEB)

    Menikoff, Ralph [Los Alamos National Laboratory

    2012-04-03

    Shock initiation in a plastic-bonded explosives (PBX) is due to hot spots. Current reactive burn models are based, at least heuristically, on the ignition and growth concept. The ignition phase occurs when a small localized region of high temperature (or hot spot) burns on a fast time scale. This is followed by a growth phase in which a reactive front spreads out from the hot spot. Propagating reactive fronts are deflagration waves. A key question is the deflagration speed in a PBX compressed and heated by a shock wave that generated the hot spot. Here, the ODEs for a steady deflagration wave profile in a compressible fluid are derived, along with the needed thermodynamic quantities of realistic equations of state corresponding to the reactants and products of a PBX. The properties of the wave profile equations are analyzed and an algorithm is derived for computing the deflagration speed. As an illustrative example, the algorithm is applied to compute the deflagration speed in shock compressed PBX 9501 as a function of shock pressure. The calculated deflagration speed, even at the CJ pressure, is low compared to the detonation speed. The implication of this are briefly discussed.

  11. Profile analysis of microparticles

    International Nuclear Information System (INIS)

    Konarski, P.; Iwanejko, I.; Mierzejewska, A.

    2001-01-01

    Depth resolved analyses of several types of microparticles are presented. Particles for secondary ion mass spectrometry (SIMS) depth profile analysis were collected in the working environment of glass plant, steelworks and welding station using eight-stage cascade impactor with particle size range of 0.3 μm to 15 μm. Ion beam sputtering and sample rotation technique allowed to describe morphology i.e. the elemental structure of collected sub-micrometer particles. Also model particles Iriodin 221 (Merck) were depth profiled. The core-shell structure is found for all types of investigated particles. Steelworks particles consist mainly of iron and manganese cores. At the shells of these microparticles: lead, chlorine and fluorine are found. The particles collected in the glass-works consist mainly of lead-zirconium glass cores covered by carbon and copper. Stainless-steel welding particles compose of iron, manganese and chromium cores covered by a shell rich in carbon, chlorine and fluorine. Sample rotation technique applied in SIMS appears to be an effective tool for environmental microparticle morphology studies

  12. Autoantibody profiling in APS.

    Science.gov (United States)

    Roggenbuck, D; Somma, V; Schierack, P; Borghi, M O; Meroni, P L

    2014-10-01

    The international consensus for the classification of antiphospholipid syndrome (APS) requires clinical and laboratory criteria to be considered at an equal level for diagnosing APS. Thus, detection of antiphospholipid antibodies (aPL) being a hallmark of APS has been the object of intensive investigation over the past 40 years. However, appropriate detection of aPL still remains a laboratory challenge due to their heterogeneity comprising autoantibodies reactive to different phospholipid-binding plasma proteins, such as beta-2 glycoprotein I (β2GPI) and prothrombin. The relevance of aPL interacting with phospholipids other than cardiolipin (CL, diphosphatidylglycerol), such as phosphatidylserine (PS), remains elusive with regard to the diagnosis of APS. Recently, the concept of aPL profiling has been introduced to assess the risk of thrombotic complications in patients with APS. New assay techniques, apart from enzyme-linked immunosorbent assays (ELISAs) recommended by the international consensus for the classification of APS, have been proposed for multiplexing of aPL testing. Line immunoassays (LIAs) employing a novel hydrophobic solid phase for the simultaneous detection of different aPL seem to be an intriguing alternative. We evaluated a novel multiplex LIA employing a hydrophobic membrane coated with different phospholipid (PL)-binding proteins or PLs. The performance characteristics of this new multiplexing assay technique demonstrated its usefulness for aPL profiling. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  13. Scalloped Implant-Abutment Connection Compared to Conventional Flat Implant-Abutment Connection

    DEFF Research Database (Denmark)

    Starch-Jensen, Thomas; Christensen, Ann-Eva; Lorenzen, Henning

    2017-01-01

    OBJECTIVES: The objective was to test the hypothesis of no difference in implant treatment outcome after installation of implants with a scalloped implant-abutment connection compared to a flat implant-abutment connection. MATERIAL AND METHODS: A MEDLINE (PubMed), Embase and Cochrane library search......-abutment connection. There were no significant differences between the two treatment modalities regarding professional or patient-reported outcome measures. Meta-analysis disclosed a mean difference of peri-implant marginal bone loss of 1.56 mm (confidence interval: 0.87 to 2.25), indicating significant more bone...... loss around implants with a scalloped implant-abutment connection. CONCLUSIONS: A scalloped implant-abutment connection seems to be associated with higher peri-implant marginal bone loss compared to a flat implant-abutment connection. Therefore, the hypothesis of the present systematic review must...

  14. General connected and reconnected fields in plasmas

    Science.gov (United States)

    Mahajan, Swadesh M.; Asenjo, Felipe A.

    2018-02-01

    For plasma dynamics, more encompassing than the magnetohydrodynamical (MHD) approximation, the foundational concepts of "magnetic reconnection" may require deep revisions because, in the larger dynamics, magnetic field is no longer connected to the fluid lines; it is replaced by more general fields (one for each plasma specie) that are weighted combination of the electromagnetic and the thermal-vortical fields. We study the two-fluid plasma dynamics plasma expressed in two different sets of variables: the two-fluid (2F) description in terms of individual fluid velocities, and the one-fluid (1F) variables comprising the plasma bulk motion and plasma current. In the 2F description, a Connection Theorem is readily established; we show that, for each specie, there exists a Generalized (Magnetofluid/Electro-Vortic) field that is frozen-in the fluid and consequently remains, forever, connected to the flow. This field is an expression of the unification of the electromagnetic, and fluid forces (kinematic and thermal) for each specie. Since the magnetic field, by itself, is not connected in the first place, its reconnection is never forbidden and does not require any external agency (like resistivity). In fact, a magnetic field reconnection (local destruction) must be interpreted simply as a consequence of the preservation of the dynamical structure of the unified field. In the 1F plasma description, however, it is shown that there is no exact physically meaningful Connection Theorem; a general and exact field does not exist, which remains connected to the bulk plasma flow. It is also shown that the helicity conservation and the existence of a Connected field follow from the same dynamical structure; the dynamics must be expressible as an ideal Ohm's law with a physical velocity. This new perspective, emerging from the analysis of the post MHD physics, must force us to reexamine the meaning as well as our understanding of magnetic reconnection.

  15. Connectivity Measures in EEG Microstructural Sleep Elements.

    Science.gov (United States)

    Sakellariou, Dimitris; Koupparis, Andreas M; Kokkinos, Vasileios; Koutroumanidis, Michalis; Kostopoulos, George K

    2016-01-01

    During Non-Rapid Eye Movement sleep (NREM) the brain is relatively disconnected from the environment, while connectedness between brain areas is also decreased. Evidence indicates, that these dynamic connectivity changes are delivered by microstructural elements of sleep: short periods of environmental stimuli evaluation followed by sleep promoting procedures. The connectivity patterns of the latter, among other aspects of sleep microstructure, are still to be fully elucidated. We suggest here a methodology for the assessment and investigation of the connectivity patterns of EEG microstructural elements, such as sleep spindles. The methodology combines techniques in the preprocessing, estimation, error assessing and visualization of results levels in order to allow the detailed examination of the connectivity aspects (levels and directionality of information flow) over frequency and time with notable resolution, while dealing with the volume conduction and EEG reference assessment. The high temporal and frequency resolution of the methodology will allow the association between the microelements and the dynamically forming networks that characterize them, and consequently possibly reveal aspects of the EEG microstructure. The proposed methodology is initially tested on artificially generated signals for proof of concept and subsequently applied to real EEG recordings via a custom built MATLAB-based tool developed for such studies. Preliminary results from 843 fast sleep spindles recorded in whole night sleep of 5 healthy volunteers indicate a prevailing pattern of interactions between centroparietal and frontal regions. We demonstrate hereby, an opening to our knowledge attempt to estimate the scalp EEG connectivity that characterizes fast sleep spindles via an "EEG-element connectivity" methodology we propose. The application of the latter, via a computational tool we developed suggests it is able to investigate the connectivity patterns related to the occurrence

  16. Interactive network analysis of the plasma amino acids profile in a mouse model of hyperglycemia

    OpenAIRE

    Tanaka, Takayuki; Mochida, Taiga; Maki, Yukihiro; Shiraki, Yasuko; Mori, Hiroko; Matsumoto, Shirou; Shimbo, Kazutaka; Ando, Toshihiko; Nakamura, Kimitoshi; Endo, Fumio; Okamoto, Masahiro

    2013-01-01

    Amino acids are a group of metabolites that are important substrates for protein synthesis, are important as signaling molecules and play central roles as highly connected metabolic hubs, and therefore, there are many reports that describe disease-specific abnormalities in plasma amino acids profile. However, the causes of progression from a healthy control to a manifestation of the plasma amino acid changes remain obscure. Here, we extended the plasma amino acids profile to relationships tha...

  17. Connectivity Neurofeedback Training Can Differentially Change Functional Connectivity and Cognitive Performance.

    Science.gov (United States)

    Yamashita, Ayumu; Hayasaka, Shunsuke; Kawato, Mitsuo; Imamizu, Hiroshi

    2017-10-01

    Advances in functional magnetic resonance imaging have made it possible to provide real-time feedback on brain activity. Neurofeedback has been applied to therapeutic interventions for psychiatric disorders. Since many studies have shown that most psychiatric disorders exhibit abnormal brain networks, a novel experimental paradigm named connectivity neurofeedback, which can directly modulate a brain network, has emerged as a promising approach to treat psychiatric disorders. Here, we investigated the hypothesis that connectivity neurofeedback can induce the aimed direction of change in functional connectivity, and the differential change in cognitive performance according to the direction of change in connectivity. We selected the connectivity between the left primary motor cortex and the left lateral parietal cortex as the target. Subjects were divided into 2 groups, in which only the direction of change (an increase or a decrease in correlation) in the experimentally manipulated connectivity differed between the groups. As a result, subjects successfully induced the expected connectivity changes in either of the 2 directions. Furthermore, cognitive performance significantly and differentially changed from preneurofeedback to postneurofeedback training between the 2 groups. These findings indicate that connectivity neurofeedback can induce the aimed direction of change in connectivity and also a differential change in cognitive performance. © The Author 2017. Published by Oxford University Press.

  18. Pore connectivity effects on solute transport in rocks

    International Nuclear Information System (INIS)

    Hu, Qinhong; Ewing, Robert P.

    2001-01-01

    Retardation of nuclear contaminants in rock matrices can lead to long retention times, allowing substantial radionuclide decay prior to eventual release. Imbibition and diffusion into the rock matrix can move contaminants away from an active fracture, thereby contributing to their retardation. However, diffusive transport in some rocks may behave anomalously because of their sparsely connected porespace, in contrast to diffusion in rocks with denser pore connections. We examined imbibition of weakly sorbing tracers into welded tuff and Indiana sandstone, and water imbibition into metagraywacke and Berea sandstone. Tuff samples were initially equilibrated to 12% and 76% water (v/v) within controlled humidity chambers, while the other rocks were air-dried. For imbibition, one face was exposed to water, with or without tracer, and uptake was measured over time. Following imbibition, tracer concentration measurements were made at fine (1 mm) increments. Three anomalous results were observed: (1) Indiana sandstone and metagraywacke showed mass of imbibed water scaling as time 0.26 , while tuff and Berea sandstone showed the more classical scaling with time 0.5 ; (2) tracer movement into dry (2% initial saturation) Indiana sandstone showed a dispersion pattern similar to that expected during tracer movement into moist (76% initial saturation) tuff; and (3) tracer concentrations at the inlet face of the tuff sample were approximately twice those deeper inside the sample. The experiment was then modeled using random walk methods on a 3-D lattice with different values of pore coordination. Network model simulations that used a pore coordination of 1.49 for Indiana sandstone and 1.56 for metagraywacke showed similar temporal scaling, a result of their porespace being close to the percolation threshold. Tracer concentration profiles in Indiana sandstone and tuff were closely matched by simulations that used pore coordinations of 1.49 and 1.68, respectively, because of how low

  19. Pore Connectivity Effects on Solute Transport in Rocks

    International Nuclear Information System (INIS)

    Oinhong Hu

    2001-01-01

    Retardation of nuclear contaminants in rock matrices can lead to long retention times, allowing substantial radionuclide decay prior to eventual release. Imbibition and diffusion into the rock matrix can move contaminants away from an active fracture, thereby contributing to their retardation. However, diffusive transport in some rocks may behave anomalously because of their sparsely connected porespace, in contrast to diffusion in rocks with denser pore connections. We examined imbibition of weakly sorbing tracers into welded tuff and Indiana sandstone, and water imbibition into metagraywacke and Berea sandstone. Tuff samples were initially equilibrated to 12% and 76% water (v/v) within controlled humidity chambers, while the other rocks were air-dried. For imbibition, one face was exposed to water, with or without tracer, and uptake was measured over time. Following imbibition, tracer concentration measurements were made at fine (1 mm) increments. Three anomalous results were observed: (1) Indiana sandstone and metagraywacke showed mass of imbibed water scaling as time 0.26 , while tuff and Berea sandstone showed the more classical scaling with time 0.05 ; (2) tracer movement into dry (2% initial saturation) Indiana sandstone showed a dispersion pattern similar to that expected during tracer movement into moist (76% initial saturation) tuft and (3) tracer concentrations at the inlet face of the tuff sample were approximately twice those deeper inside the sample. The experiment was then modeled using random walk methods on a 3-D lattice with different values of pore coordination. Network model simulations that used a pore coordination of 1.49 for Indiana sandstone and 1.56 for metagraywacke showed similar temporal scaling, a result of their porespace being close to the percolation threshold. Tracer concentration profiles in Indiana sandstone and tuff were closely matched by simulations that used pore coordinations of 1.49 and 1.68, respectively, because of how low

  20. Amygdala functional connectivity, HPA axis genetic variation, and life stress in children and relations to anxiety and emotion regulation.

    Science.gov (United States)

    Pagliaccio, David; Luby, Joan L; Bogdan, Ryan; Agrawal, Arpana; Gaffrey, Michael S; Belden, Andrew C; Botteron, Kelly N; Harms, Michael P; Barch, Deanna M

    2015-11-01

    Internalizing pathology is related to alterations in amygdala resting state functional connectivity, potentially implicating altered emotional reactivity and/or emotion regulation in the etiological pathway. Importantly, there is accumulating evidence that stress exposure and genetic vulnerability impact amygdala structure/function and risk for internalizing pathology. The present study examined whether early life stress and genetic profile scores (10 single nucleotide polymorphisms within 4 hypothalamic-pituitary-adrenal axis genes: CRHR1, NR3C2, NR3C1, and FKBP5) predicted individual differences in amygdala functional connectivity in school-age children (9- to 14-year-olds; N = 120). Whole-brain regression analyses indicated that increasing genetic "risk" predicted alterations in amygdala connectivity to the caudate and postcentral gyrus. Experience of more stressful and traumatic life events predicted weakened amygdala-anterior cingulate cortex connectivity. Genetic "risk" and stress exposure interacted to predict weakened connectivity between the amygdala and the inferior and middle frontal gyri, caudate, and parahippocampal gyrus in those children with the greatest genetic and environmental risk load. Furthermore, amygdala connectivity longitudinally predicted anxiety symptoms and emotion regulation skills at a later follow-up. Amygdala connectivity mediated effects of life stress on anxiety and of genetic variants on emotion regulation. The current results suggest that considering the unique and interacting effects of biological vulnerability and environmental risk factors may be key to understanding the development of altered amygdala functional connectivity, a potential factor in the risk trajectory for internalizing pathology. (c) 2015 APA, all rights reserved).

  1. Amygdala functional connectivity, HPA axis genetic variation, and life stress in children and relations to anxiety and emotion regulation

    Science.gov (United States)

    Pagliaccio, David; Luby, Joan L.; Bogdan, Ryan; Agrawal, Arpana; Gaffrey, Michael S.; Belden, Andrew C.; Botteron, Kelly N.; Harms, Michael P.; Barch, Deanna M.

    2015-01-01

    Internalizing pathology is related to alterations in amygdala resting state functional connectivity, potentially implicating altered emotional reactivity and/or emotion regulation in the etiological pathway. Importantly, there is accumulating evidence that stress exposure and genetic vulnerability impact amygdala structure/function and risk for internalizing pathology. The present study examined whether early life stress and genetic profile scores (10 single nucleotide polymorphisms within four hypothalamic-pituitary-adrenal axis genes: CRHR1, NR3C2, NR3C1, and FKBP5) predicted individual differences in amygdala functional connectivity in school-age children (9–14 year olds; N=120). Whole-brain regression analyses indicated that increasing genetic ‘risk’ predicted alterations in amygdala connectivity to the caudate and postcentral gyrus. Experience of more stressful and traumatic life events predicted weakened amygdala-anterior cingulate cortex connectivity. Genetic ‘risk’ and stress exposure interacted to predict weakened connectivity between the amygdala and the inferior and middle frontal gyri, caudate, and parahippocampal gyrus in those children with the greatest genetic and environmental risk load. Furthermore, amygdala connectivity longitudinally predicted anxiety symptoms and emotion regulation skills at a later follow-up. Amygdala connectivity mediated effects of life stress on anxiety and of genetic variants on emotion regulation. The current results suggest that considering the unique and interacting effects of biological vulnerability and environmental risk factors may be key to understanding the development of altered amygdala functional connectivity, a potential factor in the risk trajectory for internalizing pathology. PMID:26595470

  2. Radiometric measurement independent of profile. Belt weighers

    International Nuclear Information System (INIS)

    Otto, J.

    1986-01-01

    Radiometric measuring techniques allow contactless determination of the material carried by belt conveyors. Data defining the material is obtained via attenuation of gamma rays passing through the material on the belt. The method applies the absorption law according to Lambert-Beer, which has to be corrected by a build-up factor because of the stray radiation induced by the Compton effect. The profile-dependent error observed with conventional radiometric belt weighers is caused by the non-linearity of the absorption law in connection with the simultaneous summation of the various partial rays in a detector. The scanning method allows separate evaluation of the partial rays' attenuation and thus yields the correct data of the material carried, regardless of the profile. The scanning method is applied on a finite number of scanning sections, and a residual error has to be taken into account. The stochastics of quantum emission and absorption leads to an error whose expectation value is to be taken into account in the scanning algorithm. As the conveyor belt is in motion during the process of measurements, only part of the material conveyed is irradiated. The resulting assessment error is investigated as a function of the autocorrelation function of the material on the belt. (orig./HP) [de

  3. Portable long trace profiler: Concept and solution

    Science.gov (United States)

    Qian, Shinan; Takacs, Peter; Sostero, Giovanni; Cocco, Daniele

    2001-08-01

    Since the early development of the penta-prism long trace profiler (LTP) and the in situ LTP, and following the completion of the first in situ distortion profile measurements at Sincrotrone Trieste (ELETTRA) in Italy in 1995, a concept was developed for a compact, portable LTP with the following characteristics: easily installed on synchrotron radiation beam lines, easily carried to different laboratories around the world for measurements and calibration, convenient for use in evaluating the LTP as an in-process tool in the optical workshop, and convenient for use in temporarily installation as required by other special applications. The initial design of a compact LTP optical head was made at ELETTRA in 1995. Since 1997 further efforts to reduce the optical head size and weight, and to improve measurement stability have been made at Brookhaven National Laboratory. This article introduces the following solutions and accomplishments for the portable LTP: (1) a new design for a compact and very stable optical head, (2) the use of a small detector connected to a laptop computer directly via an enhanced parallel port, and there is no extra frame grabber interface and control box, (3) a customized small mechanical slide that uses a compact motor with a connector-sized motor controller, and (4) the use of a laptop computer system. These solutions make the portable LTP able to be packed into two laptop-size cases: one for the computer and one for the rest of the system.

  4. Portable long trace profiler: Concept and solution

    International Nuclear Information System (INIS)

    Qian, Shinan; Takacs, Peter; Sostero, Giovanni; Cocco, Daniele

    2001-01-01

    Since the early development of the penta-prism long trace profiler (LTP) and the in situ LTP, and following the completion of the first in situ distortion profile measurements at Sincrotrone Trieste (ELETTRA) in Italy in 1995, a concept was developed for a compact, portable LTP with the following characteristics: easily installed on synchrotron radiation beam lines, easily carried to different laboratories around the world for measurements and calibration, convenient for use in evaluating the LTP as an in-process tool in the optical workshop, and convenient for use in temporarily installation as required by other special applications. The initial design of a compact LTP optical head was made at ELETTRA in 1995. Since 1997 further efforts to reduce the optical head size and weight, and to improve measurement stability have been made at Brookhaven National Laboratory. This article introduces the following solutions and accomplishments for the portable LTP: (1) a new design for a compact and very stable optical head, (2) the use of a small detector connected to a laptop computer directly via an enhanced parallel port, and there is no extra frame grabber interface and control box, (3) a customized small mechanical slide that uses a compact motor with a connector-sized motor controller, and (4) the use of a laptop computer system. These solutions make the portable LTP able to be packed into two laptop-size cases: one for the computer and one for the rest of the system

  5. Connecting Network Properties of Rapidly Disseminating Epizoonotics

    Science.gov (United States)

    Rivas, Ariel L.; Fasina, Folorunso O.; Hoogesteyn, Almira L.; Konah, Steven N.; Febles, José L.; Perkins, Douglas J.; Hyman, James M.; Fair, Jeanne M.; Hittner, James B.; Smith, Steven D.

    2012-01-01

    Background To effectively control the geographical dissemination of infectious diseases, their properties need to be determined. To test that rapid microbial dispersal requires not only susceptible hosts but also a pre-existing, connecting network, we explored constructs meant to reveal the network properties associated with disease spread, which included the road structure. Methods Using geo-temporal data collected from epizoonotics in which all hosts were susceptible (mammals infected by Foot-and-mouth disease virus, Uruguay, 2001; birds infected by Avian Influenza virus H5N1, Nigeria, 2006), two models were compared: 1) ‘connectivity’, a model that integrated bio-physical concepts (the agent’s transmission cycle, road topology) into indicators designed to measure networks (‘nodes’ or infected sites with short- and long-range links), and 2) ‘contacts’, which focused on infected individuals but did not assess connectivity. Results The connectivity model showed five network properties: 1) spatial aggregation of cases (disease clusters), 2) links among similar ‘nodes’ (assortativity), 3) simultaneous activation of similar nodes (synchronicity), 4) disease flows moving from highly to poorly connected nodes (directionality), and 5) a few nodes accounting for most cases (a “20∶80″ pattern). In both epizoonotics, 1) not all primary cases were connected but at least one primary case was connected, 2) highly connected, small areas (nodes) accounted for most cases, 3) several classes of nodes were distinguished, and 4) the contact model, which assumed all primary cases were identical, captured half the number of cases identified by the connectivity model. When assessed together, the synchronicity and directionality properties explained when and where an infectious disease spreads. Conclusions Geo-temporal constructs of Network Theory’s nodes and links were retrospectively validated in rapidly disseminating infectious diseases. They distinguished

  6. Functional corticostriatal connection topographies predict goal directed behaviour in humans

    NARCIS (Netherlands)

    Marquand, A.F.; Haak, K.V.; Beckmann, C.F.

    2017-01-01

    Anatomical tracing studies in non-human primates have suggested that corticostriatal connectivity is topographically organized: nearby locations in striatum are connected with nearby locations in cortex. The topographic organization of corticostriatal connectivity is thought to underpin many

  7. Prioritizing connection requests in GMPLS-controlled optical networks

    DEFF Research Database (Denmark)

    Ruepp, Sarah Renée; Koster, A.; Andriolli, N.

    2009-01-01

    We prioritize bidirectional connection requests by combining dynamic connection provisioning with off-line optimization. Results show that the proposed approach decreases wavelength-converter usage, thereby allowing operators to reduce blocking-probably under bulk connection assignment or network...

  8. Connectivity: An emerging concept for physiotherapy practice.

    Science.gov (United States)

    Nicholls, David A; Atkinson, Karen; Bjorbækmo, Wenche S; Gibson, Barbara E; Latchem, Julie; Olesen, Jens; Ralls, Jenny; Setchell, Jennifer

    2016-01-01

    Having spent their first century anchored to a biomedical model of practice, physiotherapists have been increasingly interested in exploring new models and concepts that will better equip them for serving the health-care needs of 21st century clients/patients. Connectivity offers one such model. With an extensive philosophical background in phenomenology, symbolic interactionism, structuralism, and postmodern research, connectivity resists the prevailing western biomedical view that health professionals should aim to increase people's independence and autonomy, preferring instead to identify and amplify opportunities for collaboration and co-dependence. Connectivity critiques the normalization that underpins modern health care, arguing that our constant search for deviance is building stigma and discrimination into our everyday practice. It offers provocative opportunities for physiotherapists to rethink some of the fundamental tenets of their profession and better align physiotherapy with 21st century societal expectations. In this paper, we provide a background to the place connectivity may play in future health care, and most especially future physiotherapy practice. The paper examines some of the philosophical antecedents that have made connectivity an increasingly interesting and challenging concept in health care today.

  9. A systematic framework for functional connectivity measures

    Directory of Open Access Journals (Sweden)

    Huifang Elizabeth Wang

    2014-12-01

    Full Text Available Various methods have been proposed to characterize the functional connectivity between nodes in a network measured with different modalities (electrophysiology, functional magnetic resonance imaging etc.. Since different measures of functional connectivity yield different results for the same dataset, it is important to assess when and how they can be used. In this work, we provide a systematic framework for evaluating the performance of a large range of functional connectivity measures – based upon a comprehensive portfolio of models generating measurable responses. Specifically, we benchmarked 42 methods using 10,000 simulated datasets from 5 different types of generative models with different connectivity structures. Since all functional connectivity methods require the setting of some parameters (window size and number, model order etc., we first optimized these parameters using performance criteria based upon (threshold free ROC analysis. We then evaluated the performance of the methods on data simulated with different types of models. Finally, we assessed the performance of the methods against different levels of signal-to-noise ratios and network configurations. A MATLAB toolbox is provided to perform such analyses using other methods and simulated datasets.

  10. Bone and fat connection in aging bone.

    Science.gov (United States)

    Duque, Gustavo

    2008-07-01

    The fat and bone connection plays an important role in the pathophysiology of age-related bone loss. This review will focus on the age-induced mechanisms regulating the predominant differentiation of mesenchymal stem cells into adipocytes. Additionally, bone marrow fat will be considered as a diagnostic and therapeutic approach to osteoporosis. There are two types of bone and fat connection. The 'systemic connection', usually seen in obese patients, is hormonally regulated and associated with high bone mass and strength. The 'local connection' happens inside the bone marrow. Increasing amounts of bone marrow fat affect bone turnover through the inhibition of osteoblast function and survival and the promotion of osteoclast differentiation and activation. This interaction is regulated by paracrine secretion of fatty acids and adipokines. Additionally, bone marrow fat could be quantified using noninvasive methods and could be used as a therapeutic approach due to its capacity to transdifferentiate into bone without affecting other types of fat in the body. The bone and fat connection within the bone marrow constitutes a typical example of lipotoxicity. Additionally, bone marrow fat could be used as a new diagnostic and therapeutic approach for osteoporosis in older persons.

  11. Affine connection form of Regge calculus

    Science.gov (United States)

    Khatsymovsky, V. M.

    2016-12-01

    Regge action is represented analogously to how the Palatini action for general relativity (GR) as some functional of the metric and a general connection as independent variables represents the Einstein-Hilbert action. The piecewise flat (or simplicial) spacetime of Regge calculus is equipped with some world coordinates and some piecewise affine metric which is completely defined by the set of edge lengths and the world coordinates of the vertices. The conjugate variables are the general nondegenerate matrices on the three-simplices which play the role of a general discrete connection. Our previous result on some representation of the Regge calculus action in terms of the local Euclidean (Minkowsky) frame vectors and orthogonal connection matrices as independent variables is somewhat modified for the considered case of the general linear group GL(4, R) of the connection matrices. As a result, we have some action invariant w.r.t. arbitrary change of coordinates of the vertices (and related GL(4, R) transformations in the four-simplices). Excluding GL(4, R) connection from this action via the equations of motion we have exactly the Regge action for the considered spacetime.

  12. Connected Car: Quantified Self becomes Quantified Car

    Directory of Open Access Journals (Sweden)

    Melanie Swan

    2015-02-01

    Full Text Available The automotive industry could be facing a situation of profound change and opportunity in the coming decades. There are a number of influencing factors such as increasing urban and aging populations, self-driving cars, 3D parts printing, energy innovation, and new models of transportation service delivery (Zipcar, Uber. The connected car means that vehicles are now part of the connected world, continuously Internet-connected, generating and transmitting data, which on the one hand can be helpfully integrated into applications, like real-time traffic alerts broadcast to smartwatches, but also raises security and privacy concerns. This paper explores the automotive connected world, and describes five killer QS (Quantified Self-auto sensor applications that link quantified-self sensors (sensors that measure the personal biometrics of individuals like heart rate and automotive sensors (sensors that measure driver and passenger biometrics or quantitative automotive performance metrics like speed and braking activity. The applications are fatigue detection, real-time assistance for parking and accidents, anger management and stress reduction, keyless authentication and digital identity verification, and DIY diagnostics. These kinds of applications help to demonstrate the benefit of connected world data streams in the automotive industry and beyond where, more fundamentally for human progress, the automation of both physical and now cognitive tasks is underway.

  13. Multivariate Heteroscedasticity Models for Functional Brain Connectivity

    Directory of Open Access Journals (Sweden)

    Christof Seiler

    2017-12-01

    Full Text Available Functional brain connectivity is the co-occurrence of brain activity in different areas during resting and while doing tasks. The data of interest are multivariate timeseries measured simultaneously across brain parcels using resting-state fMRI (rfMRI. We analyze functional connectivity using two heteroscedasticity models. Our first model is low-dimensional and scales linearly in the number of brain parcels. Our second model scales quadratically. We apply both models to data from the Human Connectome Project (HCP comparing connectivity between short and conventional sleepers. We find stronger functional connectivity in short than conventional sleepers in brain areas consistent with previous findings. This might be due to subjects falling asleep in the scanner. Consequently, we recommend the inclusion of average sleep duration as a covariate to remove unwanted variation in rfMRI studies. A power analysis using the HCP data shows that a sample size of 40 detects 50% of the connectivity at a false discovery rate of 20%. We provide implementations using R and the probabilistic programming language Stan.

  14. Petroleum software profiles

    International Nuclear Information System (INIS)

    Anon.

    1996-01-01

    A profile of twenty-two software packages designed for petroleum exploration and production was provided. Some focussed on the oil and gas engineering industry, and others on mapping systems containing well history files and well data summaries. Still other programs provided accounting systems designed to address the complexities of the oil and gas industry. The software packages reviewed were developed by some of the best-known groups involved in software development for the oil and gas industry, including among others, Geoquest, the Can Tek Group, Applied Terravision Systems Inc., Neotechnology Consultants Ltd., (12) OGCI Software Inc., Oracle Energy, Production Revenue Information Systems Management, Virtual Computing Services Ltd., and geoLogic Systems Ltd

  15. Lebanon: country profile.

    Science.gov (United States)

    Marfleet, P

    1988-05-01

    A brief profile of Lebanon's economy, people, health, culture and political situation is presented. Lebanon has an estimated 3.5 million people, with a Maronite Christian elite, a Muslim Shiite majority, and Muslim Sunnis and Druze groups. The infant mortality is estimated at 41/1000; literacy is 69% among women and 86% among men; life expectancy was 66 years, 10 years ago. The economy, previously thriving on banking, manufacturing and agriculture, is now decimated, and Lebanon's once active tourist industry, based on elegant facilities in Beirut and neighboring beaches and ski slopes, is the victim of 15 years of civil strife. Israel has invaded, supporting Maronite Christians, Syria has invaded in support Muslim and Druze militias, and Iran has aggressively supported Shiite factions.

  16. Three dimensional energy profile:

    International Nuclear Information System (INIS)

    Kowsari, Reza; Zerriffi, Hisham

    2011-01-01

    The provision of adequate, reliable, and affordable energy has been considered as a cornerstone of development. More than one-third of the world's population has a very limited access to modern energy services and suffers from its various negative consequences. Researchers have been exploring various dimensions of household energy use in order to design strategies to provide secure access to modern energy services. However, despite more than three decades of effort, our understanding of household energy use patterns is very limited, particularly in the context of rural regions of the developing world. Through this paper, the past and the current trends in the field of energy analysis are investigated. The literature on rural energy and energy transition in developing world has been explored and the factors affecting households' decisions on energy use are listed. The and the factors affecting households' decisions on energy use are listed. The gaps identified in the literature on rural household energy analysis provide a basis for developing an alternative model that can create a more realistic view of household energy use. The three dimensional energy profile is presented as a new conceptual model for assessment of household energy use. This framework acts as a basis for building new theoretical and empirical models of rural household energy use. - Highlights: ► Reviews literature on household energy, energy transitions and decision-making in developing countries. ► Identifies gaps in rural household energy analysis and develops a new conceptual framework. ► The 3-d energy profile provides a holistic view of household energy system characteristics. ► Illustrates the use of the framework for understanding household energy transitions.

  17. Development of newborn screening connect (NBS connect): a self-reported patient registry and its role in improvement of care for patients with inherited metabolic disorders.

    Science.gov (United States)

    Osara, Yetsa; Coakley, Kathryn; Devarajan, Aishwarya; Singh, Rani H

    2017-07-19

    Newborn Screening Connect (NBS Connect) is a web-based self-reported patient registry and resource for individuals and families affected by disorders included in the newborn screening panel. NBS Connect was launched in 2012 by Emory University after years of planning and grassroots work by professionals, consumers, and industry. Individuals with phenylketonuria (PKU), maple syrup urine disease (MSUD) or tyrosinemia (TYR) have been recruited through distribution of outreach materials, presentations at parent organization meetings and direct recruitment at clinic appointments. Participants complete online profiles generating data on diagnosis, treatment, symptoms, outcomes, barriers to care, and quality of life. Resources such as education materials, information on the latest research and clinical trials, recipes, interactive health tracking systems, and professional support tools are described. In addition, to examine the ability of NBS Connect to generate data that guides hypothesis-driven research, data pertaining to age at diagnosis, bone health, and skin conditions in individuals with PKU were assessed. The objective of this paper is to describe the development of NBS Connect and highlight its data, resources and research contributions. In September 2016, NBS Connect had 442 registered participants: 314 (71%) individuals with PKU, 68 (15%) with MSUD, 20 (5%) with TYR, and 40 (9%) with other disorders on the NBS panel. Age at diagnosis was less than 4 weeks in 285 (89%) of 319 respondents to this question and between 1 month and 14 years in 29 (9%) individuals. Of 216 respondents with PKU, 33 (15%) had a DXA scan in the past year. Of 217 respondents with PKU, 99 (46%) reported at least one skin condition. NBS Connect was built and refined with feedback from all stakeholders, including individuals with inherited metabolic disorders. Based on patient-reported data, future studies can be initiated to test hypotheses such as the relationship between PKU and skin

  18. Beam profile measurements on RHIC

    International Nuclear Information System (INIS)

    Connolly, R.; Michnoff, R.; Moore, T.; Shea, T.; Tepikian, S.

    2000-01-01

    The Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Lab was commissioned during the summer of 1999. Transverse beam profiles on RHIC are measured with ionization profile monitors (IPMs). An IPM measures beam profiles by collecting the electrons liberated by residual gas ionization by the beam. The detector is placed in the gap of a dipole magnet to force the electrons to travel in straight lines from the beamline center to the collector. One IPM was tested and it measured the profiles of a single gold bunch containing 10 8 ions on consecutive turns. We show an example of one of these profiles giving transverse emittance. Also several profiles are combined into a mountain-range plot which shows betatron oscillations at injection

  19. Schaffer collateral inputs to CA1 excitatory and inhibitory neurons follow different connectivity rules.

    Science.gov (United States)

    Kwon, Osung; Feng, Linqing; Druckmann, Shaul; Kim, Jinhyun

    2018-05-04

    Neural circuits, governed by a complex interplay between excitatory and inhibitory neurons, are the substrate for information processing, and the organization of synaptic connectivity in neural network is an important determinant of circuit function. Here, we analyzed the fine structure of connectivity in hippocampal CA1 excitatory and inhibitory neurons innervated by Schaffer collaterals (SCs) using mGRASP in male mice. Our previous study revealed spatially structured synaptic connectivity between CA3-CA1 pyramidal cells (PCs). Surprisingly, parvalbumin-positive interneurons (PVs) showed a significantly more random pattern spatial structure. Notably, application of Peters' Rule for synapse prediction by random overlap between axons and dendrites enhanced structured connectivity in PCs, but, by contrast, made the connectivity pattern in PVs more random. In addition, PCs in a deep sublayer of striatum pyramidale appeared more highly structured than PCs in superficial layers, and little or no sublayer specificity was found in PVs. Our results show that CA1 excitatory PCs and inhibitory PVs innervated by the same SC inputs follow different connectivity rules. The different organizations of fine scale structured connectivity in hippocampal excitatory and inhibitory neurons provide important insights into the development and functions of neural networks. SIGNIFICANCE STATEMENT Understanding how neural circuits generate behavior is one of the central goals of neuroscience. An important component of this endeavor is the mapping of fine-scale connection patterns that underlie, and help us infer, signal processing in the brain. Here, using our recently developed synapse detection technology (mGRASP and neuTube), we provide detailed profiles of synaptic connectivity in excitatory (CA1 pyramidal) and inhibitory (CA1 parvalbumin-positive) neurons innervated by the same presynaptic inputs (CA3 Schaffer collaterals). Our results reveal that these two types of CA1 neurons follow

  20. Tight connection between fission gas discharge channels

    International Nuclear Information System (INIS)

    Jung, W.; Peehs, M.; Rau, P.; Krug, W.; Stechemesser, H.

    1978-01-01

    The invention is concerned with the tight connection between the fission gas discharge channel, leading away from the support plate of a gas-cooled reactor, and the top of the fuel element suspended from this support plate. The closure is designed to be gas-tight for the suspended as well as for the released fuel element. The tight connection has got an annular body resting on the core support plate in the mouth region of the fission gas discharge channel. This body is connected with the fission gas discharge channel in the fuel element top fitting via a gas-tight part and supported by a compression spring. Care is taken for sealing if the fuel element is removal. (RW) [de

  1. A Model of Trusted Connection Architecture

    Directory of Open Access Journals (Sweden)

    Zhang Xun

    2017-01-01

    Full Text Available According to that traditional trusted network connection architecture (TNC has limitations on dynamic network environment and the user behavior support, we develop TCA to propose a trusted connection architecture supporting behavior measurement (TCA-SBM, besides, the structure diagram of network architecture is given. Through introducing user behavior measure elements, TCA-SBM can conduct measurement on the whole network in time dimension periodically, and refine the measurement on network behavior in measure dimension to conduct fine-grained dynamic trusted measurement. As a result, TCA-SBM enhances the TCA’s ability to adapt to the dynamic change of network and makes up the deficiency of trusted computing framework in the network connection.

  2. Robust quantum optimizer with full connectivity.

    Science.gov (United States)

    Nigg, Simon E; Lörch, Niels; Tiwari, Rakesh P

    2017-04-01

    Quantum phenomena have the potential to speed up the solution of hard optimization problems. For example, quantum annealing, based on the quantum tunneling effect, has recently been shown to scale exponentially better with system size than classical simulated annealing. However, current realizations of quantum annealers with superconducting qubits face two major challenges. First, the connectivity between the qubits is limited, excluding many optimization problems from a direct implementation. Second, decoherence degrades the success probability of the optimization. We address both of these shortcomings and propose an architecture in which the qubits are robustly encoded in continuous variable degrees of freedom. By leveraging the phenomenon of flux quantization, all-to-all connectivity with sufficient tunability to implement many relevant optimization problems is obtained without overhead. Furthermore, we demonstrate the robustness of this architecture by simulating the optimal solution of a small instance of the nondeterministic polynomial-time hard (NP-hard) and fully connected number partitioning problem in the presence of dissipation.

  3. CELLULAR CONTROL OF CONNECTIVE TISSUE MATRIX TENSION†

    Science.gov (United States)

    Langevin, Helene M.; Nedergaard, Maiken; Howe, Alan

    2013-01-01

    The biomechanical behavior of connective tissue in response to stretching is generally attributed to the molecular composition and organization of its extracellular matrix. It also is becoming apparent that fibroblasts play an active role in regulating connective tissue tension. In response to static stretching of the tissue, fibroblasts expand within minutes by actively remodeling their cytoskeleton. This dynamic change in fibroblast shape contributes to the drop in tissue tension that occurs during viscoelastic relaxation. We propose that this response of fibroblasts plays a role in regulating extracellular fluid flow into the tissue, and protects against swelling when the matrix is stretched. This article reviews the evidence supporting possible mechanisms underlying this response including autocrine purinergic signaling. We also discuss fibroblast regulation of connective tissue tension with respect to lymphatic flow, immune function and cancer. PMID:23444198

  4. Connections between algebra, combinatorics, and geometry

    CERN Document Server

    Sather-Wagstaff, Sean

    2014-01-01

    Commutative algebra, combinatorics, and algebraic geometry are thriving areas of mathematical research with a rich history of interaction. Connections Between Algebra, Combinatorics, and Geometry contains lecture notes, along with exercises and solutions, from the Workshop on Connections Between Algebra and Geometry held at the University of Regina from May 29-June 1, 2012. It also contains research and survey papers from academics invited to participate in the companion Special Session on Interactions Between Algebraic Geometry and Commutative Algebra, which was part of the CMS Summer Meeting at the University of Regina held June 2–3, 2012, and the meeting Further Connections Between Algebra and Geometry, which was held at the North Dakota State University, February 23, 2013. This volume highlights three mini-courses in the areas of commutative algebra and algebraic geometry: differential graded commutative algebra, secant varieties, and fat points and symbolic powers. It will serve as a useful resou...

  5. Supervised hub-detection for brain connectivity

    DEFF Research Database (Denmark)

    Kasenburg, Niklas; Liptrot, Matthew George; Reislev, Nina Linde

    2016-01-01

    , but can smooth discriminative signals in the population, degrading predictive performance. We present a novel hub-detection optimized for supervised learning that both clusters network nodes based on population level variation in connectivity and also takes the learning problem into account. The found......A structural brain network consists of physical connections between brain regions. Brain network analysis aims to find features associated with a parameter of interest through supervised prediction models such as regression. Unsupervised preprocessing steps like clustering are often applied...... hubs are a low-dimensional representation of the network and are chosen based on predictive performance as features for a linear regression. We apply our method to the problem of finding age-related changes in structural connectivity. We compare our supervised hub-detection (SHD) to an unsupervised hub...

  6. Evolution Strategies in the Multipoint Connections Routing

    Directory of Open Access Journals (Sweden)

    L. Krulikovska

    2010-09-01

    Full Text Available Routing of multipoint connections plays an important role in final cost and quality of a found connection. New algorithms with better results are still searched. In this paper, a possibility of using the evolution strategies (ES for routing is presented. Quality of found connection is evaluated from the view of final cost and time spent on a searching procedure. First, parametrical analysis of results of the ES are discussed and compared with the Prim’s algorithm, which was chosen as a representative of the deterministic routing algorithms. Second, ways for improving the ES are suggested and implemented. The obtained results are reviewed. The main improvements are specified and discussed in conclusion.

  7. Eccentric connectivity index of chemical trees

    International Nuclear Information System (INIS)

    Haoer, R. S.; Atan, K. A.; Said, M. R. Md.; Khalaf, A. M.; Hasni, R.

    2016-01-01

    Let G = (V, E) be a simple connected molecular graph. In such a simple molecular graph, vertices and edges are depicted atoms and chemical bonds respectively, we refer to the sets of vertices by V (G) and edges by E (G). If d(u, v) be distance between two vertices u, v ∈ V(G) and can be defined as the length of a shortest path joining them. Then, the eccentricity connectivity index (ECI) of a molecular graph G is ξ(G) = ∑_v_∈_V_(_G_) d(v) ec(v), where d(v) is degree of a vertex v ∈ V(G). ec(v) is the length of a greatest path linking to another vertex of v. In this study, we focus the general formula for the eccentricity connectivity index (ECI) of some chemical trees as alkenes.

  8. Unwrapping Court-Connected Mediation Agreements

    DEFF Research Database (Denmark)

    Adrian, Lin; Mykland, Solfrid

    2018-01-01

    Court-connected mediated agreements seem to both fulfil and fail the ideal of self-determination in mediation theory. In a study of 134 agreements from court-connected mediation, we found that the majority of agreements contain creative elements and display great variation in the provisions...... and understand them. The judicial language is well known for the drafters of the agreement but not the parties. Thus, court-connected mediation seems to fail aspects of self-determination when it comes to drafting agreements. We draw on new-institutional theory when we explore and explain this apparent...... they contain. These results indicate that the parties play an important role in crafting the substance of their agreements. However, we also found that the wording of the agreements is characterised by legal and bureaucratic language to the extent that people without legal training find it difficult to read...

  9. Phase synchronization in train connection timetables

    Energy Technology Data Exchange (ETDEWEB)

    Fretter, Christoph; Mueller-Hannemann, Matthias [Martin Luther Universitaet, Halle-Wittenberg (Germany); Krumov, Lachezar; Weihe, Karsten [TU Darmstadt (Germany); Huett, Marc-Thorsten [Jacobs University, Bremen (Germany)

    2010-07-01

    Train connection timetables are an important research topic in algorithmics. Finding optimal or near-optimal timetables under the subsidiary conditions of minimizing travel times and other criteria is an important contribution to the functioning of public transportation. In addition to efficiency (given, e.g. by minimal average travel times), the robustness of the timetable, i.e. a minimization of delay propagation, is an important criterion. Here we study the balance of efficiency and robustness in train connection timetables from the perspective of synchronization, exploiting the fact that a major part of the trains run nearly periodically. We find that synchronization is highest at intermediate-sized stations. We argue that this synchronization perspectives opens a new avenue towards an understanding of train connection timetables by representing them as spatiotemporal phase patterns. Robustness and efficiency can then be viewed as properties of this phase pattern.

  10. Cellular control of connective tissue matrix tension.

    Science.gov (United States)

    Langevin, Helene M; Nedergaard, Maiken; Howe, Alan K

    2013-08-01

    The biomechanical behavior of connective tissue in response to stretching is generally attributed to the molecular composition and organization of its extracellular matrix. It also is becoming apparent that fibroblasts play an active role in regulating connective tissue tension. In response to static stretching of the tissue, fibroblasts expand within minutes by actively remodeling their cytoskeleton. This dynamic change in fibroblast shape contributes to the drop in tissue tension that occurs during viscoelastic relaxation. We propose that this response of fibroblasts plays a role in regulating extracellular fluid flow into the tissue, and protects against swelling when the matrix is stretched. This article reviews the evidence supporting possible mechanisms underlying this response including autocrine purinergic signaling. We also discuss fibroblast regulation of connective tissue tension with respect to lymphatic flow, immune function, and cancer. Copyright © 2013 Wiley Periodicals, Inc.

  11. Connections with nature and environmental behaviors.

    Science.gov (United States)

    Geng, Liuna; Xu, Jingke; Ye, Lijuan; Zhou, Wenjun; Zhou, Kexin

    2015-01-01

    The influence of environmental attitudes on environmental behaviors has long been discussed. However, few studies have addressed the foundation of such attitudes. In the present study, we explored primitive belief underlying environmental attitudes, i.e., connections with nature, and its relationship with pro-environmental behaviors. Specifically, we used scales, a computerized Implicit Association Test, and a situational simulation experiment to examine both explicit and implicit connections with nature, both deliberate and spontaneous environmental behaviors, and to find correlations between environmental connectedness and environmental behaviors. Results showed that explicit connectedness was positively correlated with deliberate environmental behaviors, while implicit connectedness was positively correlated with spontaneous environmental behaviors. Additionally, explicit and implicit connectedness was independent of each other. In conclusion, the current study confirms the positive role played by connections with nature in promoting environmental behavior, and accordingly suggests means to encourage pro-environmental behavior by enhancing people's connectedness to nature.

  12. Increased precuneus connectivity during propofol sedation.

    Science.gov (United States)

    Liu, Xiaolin; Li, Shi-Jiang; Hudetz, Anthony G

    2014-02-21

    Using functional magnetic resonance imaging in human participants, we show that sedation by propofol to the point of lost overt responsiveness during the performance of an auditory verbal memory task unexpectedly increases functional connectivity of the precuneus with cortical regions, particularly the dorsal prefrontal and visual cortices. After recovery of consciousness, functional connectivity returns to a pattern similar to that observed during the wakeful baseline. In the context of a recent proposal that highlights the uncoupling of consciousness, connectedness, and responsiveness in general anesthesia, the increased precuneus functional connectivity under propofol sedation may reflect disconnected endogenous mentation or dreaming that continues at a reduced level of metabolic activity. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  13. Quantifying Riverscape Connectivity with Graph Theory

    Science.gov (United States)

    Carbonneau, P.; Milledge, D.; Sinha, R.; Tandon, S. K.

    2013-12-01

    Fluvial catchments convey fluxes of water, sediment, nutrients and aquatic biota. At continental scales, crustal topography defines the overall path of channels whilst at local scales depositional and/or erosional features generally determine the exact path of a channel. Furthermore, constructions such as dams, for either water abstraction or hydropower, often have a significant impact on channel networks.The concept of ';connectivity' is commonly invoked when conceptualising the structure of a river network.This concept is easy to grasp but there have been uneven efforts across the environmental sciences to actually quantify connectivity. Currently there have only been a few studies reporting quantitative indices of connectivity in river sciences, notably, in the study of avulsion processes. However, the majority of current work describing some form of environmental connectivity in a quantitative manner is in the field of landscape ecology. Driven by the need to quantify habitat fragmentation, landscape ecologists have returned to graph theory. Within this formal setting, landscape ecologists have successfully developed a range of indices which can model connectivity loss. Such formal connectivity metrics are currently needed for a range of applications in fluvial sciences. One of the most urgent needs relates to dam construction. In the developed world, hydropower development has generally slowed and in many countries, dams are actually being removed. However, this is not the case in the developing world where hydropower is seen as a key element to low-emissions power-security. For example, several dam projects are envisaged in Himalayan catchments in the next 2 decades. This region is already under severe pressure from climate change and urbanisation, and a better understanding of the network fragmentation which can be expected in this system is urgently needed. In this paper, we apply and adapt connectivity metrics from landscape ecology. We then examine the

  14. Soft Computing Methods for Disulfide Connectivity Prediction.

    Science.gov (United States)

    Márquez-Chamorro, Alfonso E; Aguilar-Ruiz, Jesús S

    2015-01-01

    The problem of protein structure prediction (PSP) is one of the main challenges in structural bioinformatics. To tackle this problem, PSP can be divided into several subproblems. One of these subproblems is the prediction of disulfide bonds. The disulfide connectivity prediction problem consists in identifying which nonadjacent cysteines would be cross-linked from all possible candidates. Determining the disulfide bond connectivity between the cysteines of a protein is desirable as a previous step of the 3D PSP, as the protein conformational search space is highly reduced. The most representative soft computing approaches for the disulfide bonds connectivity prediction problem of the last decade are summarized in this paper. Certain aspects, such as the different methodologies based on soft computing approaches (artificial neural network or support vector machine) or features of the algorithms, are used for the classification of these methods.

  15. Healthcare e-commerce: connecting with patients.

    Science.gov (United States)

    Joslyn, J S

    2001-01-01

    Electronically connecting with patients is a challenging frontier at which technical hurdles are probably exceeded by political, legal, and other barriers. The rise of consumerism, however, compels a response focused more on revenue and strategic advantage than on pure cost savings. Among the difficulties faced by providers is choosing among various models of connectivity and component function. Emerging models include "free-floating" personal medical records largely independent of the office-based physician, systems with compatible and intertwined physician and consumer relationships using an application services provider office practice system, and systems that connect patients and providers through e-mail, office triage, prescription refills, scheduling, and so on. This article discusses these and other combinations of technology that significantly overcome the barriers involved and that may be woven together to provide solutions uniquely suited to various competitive situations.

  16. Political Connections and Investment in Rural Vietnam

    DEFF Research Database (Denmark)

    Markussen, Thomas; Tarp, Finn

    This paper uses household panel data from rural Vietnam to explore the effects of having a relative in a position of political or bureaucratic power on farmers’ agricultural investment decisions. Our main result is that households significantly increase their investment in land improvement...... as a result of relatives moving into public office. Connections to office holders appear to be important for investment because they strengthen de facto land property rights and improve access to off-farm employment and to informal loans. The findings underline the importance of informal networks for economic...... behaviour in environments with developing institutions and markets. They also suggest the presence of an untapped potential for economic development: if households without connections could obtain equally strong property rights and access to credit and insurance as the well-connected households, investment...

  17. LR: Compact connectivity representation for triangle meshes

    Energy Technology Data Exchange (ETDEWEB)

    Gurung, T; Luffel, M; Lindstrom, P; Rossignac, J

    2011-01-28

    We propose LR (Laced Ring) - a simple data structure for representing the connectivity of manifold triangle meshes. LR provides the option to store on average either 1.08 references per triangle or 26.2 bits per triangle. Its construction, from an input mesh that supports constant-time adjacency queries, has linear space and time complexity, and involves ordering most vertices along a nearly-Hamiltonian cycle. LR is best suited for applications that process meshes with fixed connectivity, as any changes to the connectivity require the data structure to be rebuilt. We provide an implementation of the set of standard random-access, constant-time operators for traversing a mesh, and show that LR often saves both space and traversal time over competing representations.

  18. Functional connectivity of emotional processing in depression.

    LENUS (Irish Health Repository)

    Carballedo, Angela

    2012-02-01

    OBJECTIVES: The aim of the study is to map a neural network of emotion processing and to identify differences in major depression compared to healthy controls. It is hypothesized that intentional perception of emotional faces activates connections between amygdala (Demir et al.), orbitofrontal cortex (OFC), anterior cingulate cortex (ACC) and prefrontal cortex (PFC) and that frontal-amygdala connections are altered in major depressive disorder (MDD). METHODS: Fifteen medication-free patients with MDD and fifteen healthy controls were enrolled. All subjects were assessed using the same face-matching functional Magnetic Resonance Imaging (fMRI) task, known to involve those areas. Brain activations were obtained using Statistical Parametric Mapping version 5 (SPM5) for data analysis and MARSBAR for extracting of fMRI time series. Then data was analyzed using structural equation modeling (SEM). RESULTS: A valid model was established for the left and the right hemispheres showing a circuit involving ACC, OFC, PFC and AMY. The left hemisphere shows significant lower connectivity strengths in patients than controls, for the pathway that goes from AMY to the OF11, and a trend of higher connectivity in patients for the path that goes from the PF9 to the OF11. In the right hemisphere, patients show lower connectivity coefficients in the paths from the AMY to OF11, from the AMY to ACC, and from the ACC to PF9. By the contrary, controls show lower connectivity strengths for the path that goes from ACC to AMY. CONCLUSIONS: Functional disconnection between limbic and frontal brain regions could be demonstrated using structural equation modeling. The interpretation of these findings could be that there is an emotional processing bias with disconnection bilaterally between amygdala to orbitofrontal cortices and in addition a right disconnection between amygdala and ACC as well as between ACC and prefrontal cortex possibly in line with a more prominent role for the right hemisphere

  19. Competency profile of Fitness Instructor

    OpenAIRE

    Peterová, Marta

    2011-01-01

    Title: COMPETENCY PROFILE OF FITNESS INSTRUCTOR Objectives: The aim of this work is to find out competencies of fitness instructor and make a competency profile, containing competencies, which are important for excellent fitness instructor. Methods: I applied the method of interview and the method of research in my thesis. The interview was used to make a list of competencies of fitness instructor. The research was applied in the final part of making competency profile, for an attestation of ...

  20. Institutional Profiles: Some Strategic Tools

    Directory of Open Access Journals (Sweden)

    Frans van Vught

    2014-04-01

    Full Text Available In this paper we argue that both internal and external pressures and conditions urge contemporary higher education institutions to carefully think through their institutional profiles positions in domestic and global higher education contexts. We subsequently analyse strategic positioning from the strategic management literature and offer four tools — mapping, multi-dimensional ranking, benchmarking and degree profiling — to assist higher education institutions in their profiling and positioning strategies.

  1. Machine for welding solar cell connections

    Energy Technology Data Exchange (ETDEWEB)

    Lorans, D.Y.

    1977-08-09

    A machine for welding a connection wire over a solar cell electrode is described which comprises a base, a welding mount for the solar cell which is supported on the base, means for holding the solar cell on the welding mount, welding electrodes, means to lower the welding electrodes over the solar cell and the connection wire superimposed thereon, means for applying electric current pulses to said welding electrodes. It is characterized by the fact that it further comprises means for imparting to said mount an alternating transverse movement in relation to said base before and during the welding operation.

  2. Connected Colourings of Complete Graphs and Hypergraphs

    OpenAIRE

    Leader, Imre; Tan, Ta Sheng

    2014-01-01

    Gallai's colouring theorem states that if the edges of a complete graph are 3-coloured, with each colour class forming a connected (spanning) subgraph, then there is a triangle that has all 3 colours. What happens for more colours: if we $k$-colour the edges of the complete graph, with each colour class connected, how many of the $\\binom{k}{3}$ triples of colours must appear as triangles? In this note we show that the `obvious' conjecture, namely that there are always at least $\\binom{k-1}{2}...

  3. Multimodal Imaging Brain Connectivity Analysis (MIBCA toolbox

    Directory of Open Access Journals (Sweden)

    Andre Santos Ribeiro

    2015-07-01

    Full Text Available Aim. In recent years, connectivity studies using neuroimaging data have increased the understanding of the organization of large-scale structural and functional brain networks. However, data analysis is time consuming as rigorous procedures must be assured, from structuring data and pre-processing to modality specific data procedures. Until now, no single toolbox was able to perform such investigations on truly multimodal image data from beginning to end, including the combination of different connectivity analyses. Thus, we have developed the Multimodal Imaging Brain Connectivity Analysis (MIBCA toolbox with the goal of diminishing time waste in data processing and to allow an innovative and comprehensive approach to brain connectivity.Materials and Methods. The MIBCA toolbox is a fully automated all-in-one connectivity toolbox that offers pre-processing, connectivity and graph theoretical analyses of multimodal image data such as diffusion-weighted imaging, functional magnetic resonance imaging (fMRI and positron emission tomography (PET. It was developed in MATLAB environment and pipelines well-known neuroimaging softwares such as Freesurfer, SPM, FSL, and Diffusion Toolkit. It further implements routines for the construction of structural, functional and effective or combined connectivity matrices, as well as, routines for the extraction and calculation of imaging and graph-theory metrics, the latter using also functions from the Brain Connectivity Toolbox. Finally, the toolbox performs group statistical analysis and enables data visualization in the form of matrices, 3D brain graphs and connectograms. In this paper the MIBCA toolbox is presented by illustrating its capabilities using multimodal image data from a group of 35 healthy subjects (19–73 years old with volumetric T1-weighted, diffusion tensor imaging, and resting state fMRI data, and 10 subjets with 18F-Altanserin PET data also.Results. It was observed both a high inter

  4. Differential geometry bundles, connections, metrics and curvature

    CERN Document Server

    Taubes, Clifford Henry

    2011-01-01

    Bundles, connections, metrics and curvature are the 'lingua franca' of modern differential geometry and theoretical physics. This book will supply a graduate student in mathematics or theoretical physics with the fundamentals of these objects. Many of the tools used in differential topology are introduced and the basic results about differentiable manifolds, smooth maps, differential forms, vector fields, Lie groups, and Grassmanians are all presented here. Other material covered includes the basic theorems about geodesics and Jacobi fields, the classification theorem for flat connections, the

  5. Emerging connections between RNA and autophagy

    DEFF Research Database (Denmark)

    Frankel, Lisa B; Lubas, Michal; Lund, Anders H

    2017-01-01

    in yeast, plants and animals, reviewing the molecular mechanisms and biological importance in normal physiology, stress and disease. In addition, we explore emerging evidence of core autophagy regulation mediated by RNA-binding proteins and noncoding RNAs, and point to gaps in our current knowledge......Macroautophagy/autophagy is a key catabolic process, essential for maintaining cellular homeostasis and survival through the removal and recycling of unwanted cellular material. Emerging evidence has revealed intricate connections between the RNA and autophagy research fields. While a majority...... of the connection between RNA and autophagy. Finally, we discuss the pathological implications of RNA-protein aggregation, primarily in the context of neurodegenerative disease....

  6. Connections and curvatures on complex Riemannian manifolds

    International Nuclear Information System (INIS)

    Ganchev, G.; Ivanov, S.

    1991-05-01

    Characteristic connection and characteristic holomorphic sectional curvatures are introduced on a complex Riemannian manifold (not necessarily with holomorphic metric). For the class of complex Riemannian manifolds with holomorphic characteristic connection a classification of the manifolds with (pointwise) constant holomorphic characteristic curvature is given. It is shown that the conformal geometry of complex analytic Riemannian manifolds can be naturally developed on the class of locally conformal holomorphic Riemannian manifolds. Complex Riemannian manifolds locally conformal to the complex Euclidean space are characterized with zero conformal fundamental tensor and zero conformal characteristic tensor. (author). 12 refs

  7. Connection of thin-walled casings

    Energy Technology Data Exchange (ETDEWEB)

    Druyan, V.M.; Grinev, A.F.; Gruzdev, V.D.; Perchanik, V.V.; Syplenko, V.T.

    1981-08-28

    A connection is suggested for castings which contains a nipple and coupling part with conical triangular threading. in order to improve the strength of the connection of thin-walled casings with ratio D/S>22, where D is the outer diameter of the casing, S is the thickness of the wall of the casing, the end of the pipe on the length from the end to the main plane of the thread is conical with constant thickness of the wall and conicity eqal to the conicity of the thread.

  8. Banding of connection standards for distributed generation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-05-04

    This report presents the views of distributed network operators (DNOs), developers, equipment manufacturers and consultants on the current banding of distributed generation in terms of connection standards and recommendations. The Documents ER G59/1, ER G75/1, ER G83/1 and ETR 113/1 covering recommendations for the connection of embedded generating plant to distribution systems and guidance notes for the protection of embedded generating plant are examined. The way in which the recommendations are applied in practice is investigated. Multiple distribution generator installations, fault ride through, and banding are considered as well as both protection required and maximum generator sizes at respective voltage levels.

  9. Internet services for planning distributed generation connections

    Energy Technology Data Exchange (ETDEWEB)

    Curry, D.; Morgan, A.; Barbier, C.; Reay, P.

    2005-07-01

    The required publication by distributed network operators (DNOs) of details of the current state of their network systems and future planned developments in the form of Long Term Development Statements (LTDS) are discussed. This project aims to increase the usefulness of the information in the LTDS by making it available on the internet and by providing an initial assessment of connection opportunities and the possibility of viewing existing renewable generation projects. The services developed covered data loading, data visualisation, security, connection assessment, reporting, and generation site registration. The benefits of an electronic version of the LTDS are highlighted.

  10. Inter- and intrahemispheric connectivity differences when reading Japanese Kanji and Hiragana.

    Science.gov (United States)

    Kawabata Duncan, Keith J; Twomey, Tae; Parker Jones, 'Ōiwi; Seghier, Mohamed L; Haji, Tomoki; Sakai, Katsuyuki; Price, Cathy J; Devlin, Joseph T

    2014-06-01

    Unlike most languages that are written using a single script, Japanese uses multiple scripts including morphographic Kanji and syllabographic Hiragana and Katakana. Here, we used functional magnetic resonance imaging with dynamic causal modeling to investigate competing theories regarding the neural processing of Kanji and Hiragana during a visual lexical decision task. First, a bilateral model investigated interhemispheric connectivity between ventral occipito-temporal (vOT) cortex and Broca's area ("pars opercularis"). We found that Kanji significantly increased the connection strength from right-to-left vOT. This is interpreted in terms of increased right vOT activity for visually complex Kanji being integrated into the left (i.e. language dominant) hemisphere. Secondly, we used a unilateral left hemisphere model to test whether Kanji and Hiragana rely preferentially on ventral and dorsal paths, respectively, that is, they have different intrahemispheric functional connectivity profiles. Consistent with this hypothesis, we found that Kanji increased connectivity within the ventral path (V1 ↔ vOT ↔ Broca's area), and that Hiragana increased connectivity within the dorsal path (V1 ↔ supramarginal gyrus ↔ Broca's area). Overall, the results illustrate how the differential processing demands of Kanji and Hiragana influence both inter- and intrahemispheric interactions.

  11. Continuation of connecting orbits in 3d-ODEs. (ii) cycle-to-cycle connections.

    NARCIS (Netherlands)

    Doedel, E.J.; Kooi, B.W.; van Voorn, G.A.K.; Kuznetzov, Y.A.

    2009-01-01

    In Part I of this paper we have discussed new methods for the numerical continuation of point-to-cycle connecting orbits in three-dimensional autonomous ODE's using projection boundary conditions. In this second part we extend the method to the numerical continuation of cycle-to-cycle connecting

  12. A review of variables of urban street connectivity for spatial connection

    International Nuclear Information System (INIS)

    Mohamad, W S N W; Said, I

    2014-01-01

    Several studies on street connectivity in cities and towns have been modeled on topology, morphology, technology and psychology of people living in the urban environment. Street connectivity means the connection of streets that offers people alternative routes. However, there emerge difficulties to determine the suitable variables and analysis to be chosen in defining the accurate result for studies street connectivity. The aim of this paper is to identify variables of street connectivity by applying GIS and Space Syntax. This paper reviews the variables of street connectivity from 15 past articles done in 1990s to early 2000s from journals of nine disciplines on Environment and Behavior, Planning and Design, Computers, Environment and Urban Systems, Applied Earth Observation and Geo-information, Environment and Planning, Physica A: Statistical Mechanics and its Applications, Environmental Psychology, Social Science and Medicine and Building and Environment. From the review, there are four variables found for street connectivity: link (streets-streets, street-nodes or node-streets, nodes-nodes), accessibility, least-angle, and centrality. Space syntax and GIS are suitable tools to analyze the four variables relating to systematic street systems for pedestrians. This review implies that planners of the street systems, in the aspect of street connectivity in cities and towns, should consider these four variables

  13. A review of variables of urban street connectivity for spatial connection

    Science.gov (United States)

    Mohamad, W. S. N. W.; Said, I.

    2014-02-01

    Several studies on street connectivity in cities and towns have been modeled on topology, morphology, technology and psychology of people living in the urban environment. Street connectivity means the connection of streets that offers people alternative routes. However, there emerge difficulties to determine the suitable variables and analysis to be chosen in defining the accurate result for studies street connectivity. The aim of this paper is to identify variables of street connectivity by applying GIS and Space Syntax. This paper reviews the variables of street connectivity from 15 past articles done in 1990s to early 2000s from journals of nine disciplines on Environment and Behavior, Planning and Design, Computers, Environment and Urban Systems, Applied Earth Observation and Geo-information, Environment and Planning, Physica A: Statistical Mechanics and its Applications, Environmental Psychology, Social Science and Medicine and Building and Environment. From the review, there are four variables found for street connectivity: link (streets-streets, street-nodes or node-streets, nodes-nodes), accessibility, least-angle, and centrality. Space syntax and GIS are suitable tools to analyze the four variables relating to systematic street systems for pedestrians. This review implies that planners of the street systems, in the aspect of street connectivity in cities and towns, should consider these four variables.

  14. Scalloped Implant-Abutment Connection Compared to Conventional Flat Implant-Abutment Connection

    DEFF Research Database (Denmark)

    Starch-Jensen, Thomas; Christensen, Ann-Eva; Lorenzen, Henning

    2017-01-01

    OBJECTIVES: The objective was to test the hypothesis of no difference in implant treatment outcome after installation of implants with a scalloped implant-abutment connection compared to a flat implant-abutment connection. MATERIAL AND METHODS: A MEDLINE (PubMed), Embase and Cochrane library search...... of suprastructures has never been compared within the same study. High implant survival rate was reported in all the included studies. Significantly more peri-implant marginal bone loss, higher probing depth score, bleeding score and gingival score was observed around implants with a scalloped implant-abutment...... loss around implants with a scalloped implant-abutment connection. CONCLUSIONS: A scalloped implant-abutment connection seems to be associated with higher peri-implant marginal bone loss compared to a flat implant-abutment connection. Therefore, the hypothesis of the present systematic review must...

  15. Flocking of Second-Order Multiagent Systems With Connectivity Preservation Based on Algebraic Connectivity Estimation.

    Science.gov (United States)

    Fang, Hao; Wei, Yue; Chen, Jie; Xin, Bin

    2017-04-01

    The problem of flocking of second-order multiagent systems with connectivity preservation is investigated in this paper. First, for estimating the algebraic connectivity as well as the corresponding eigenvector, a new decentralized inverse power iteration scheme is formulated. Then, based on the estimation of the algebraic connectivity, a set of distributed gradient-based flocking control protocols is built with a new class of generalized hybrid potential fields which could guarantee collision avoidance, desired distance stabilization, and the connectivity of the underlying communication network simultaneously. What is important is that the proposed control scheme allows the existing edges to be broken without violation of connectivity constraints, and thus yields more flexibility of motions and reduces the communication cost for the multiagent system. In the end, nontrivial comparative simulations and experimental results are performed to demonstrate the effectiveness of the theoretical results and highlight the advantages of the proposed estimation scheme and control algorithm.

  16. Thalamotemporal impairment in temporal lobe epilepsy: a combined MRI analysis of structure, integrity, and connectivity.

    Science.gov (United States)

    Keller, Simon S; O'Muircheartaigh, Jonathan; Traynor, Catherine; Towgood, Karren; Barker, Gareth J; Richardson, Mark P

    2014-02-01

    Thalamic abnormality in temporal lobe epilepsy (TLE) is well known from imaging studies, but evidence is lacking regarding connectivity profiles of the thalamus and their involvement in the disease process. We used a novel multisequence magnetic resonance imaging (MRI) protocol to elucidate the relationship between mesial temporal and thalamic pathology in TLE. For 23 patients with TLE and 23 healthy controls, we performed T1 -weighted (for analysis of tissue structure), diffusion tensor imaging (tissue connectivity), and T1 and T2 relaxation (tissue integrity) MRI across the whole brain. We used connectivity-based segmentation to determine connectivity patterns of thalamus to ipsilateral cortical regions (occipital, parietal, prefrontal, postcentral, precentral, and temporal). We subsequently determined volumes, mean tractography streamlines, and mean T1 and T2 relaxometry values for each thalamic segment preferentially connecting to a given cortical region, and of the hippocampus and entorhinal cortex. As expected, patients had significant volume reduction and increased T2 relaxation time in ipsilateral hippocampus and entorhinal cortex. There was bilateral volume loss, mean streamline reduction, and T2 increase of the thalamic segment preferentially connected to temporal lobe, corresponding to anterior, dorsomedial, and pulvinar thalamic regions, with no evidence of significant change in any other thalamic segments. Left and right thalamotemporal segment volume and T2 were significantly correlated with volume and T2 of ipsilateral (epileptogenic), but not contralateral (nonepileptogenic), mesial temporal structures. These convergent and robust data indicate that thalamic abnormality in TLE is restricted to the area of the thalamus that is preferentially connected to the epileptogenic temporal lobe. The degree of thalamic pathology is related to the extent of mesial temporal lobe damage in TLE. © 2014 The Authors. Epilepsia published by Wiley Periodicals, Inc

  17. Steel Rack Connections: Identification of Most Influential Factors and a Comparison of Stiffness Design Methods.

    Directory of Open Access Journals (Sweden)

    S N R Shah

    Full Text Available Steel pallet rack (SPR beam-to-column connections (BCCs are largely responsible to avoid the sway failure of frames in the down-aisle direction. The overall geometry of beam end connectors commercially used in SPR BCCs is different and does not allow a generalized analytic approach for all types of beam end connectors; however, identifying the effects of the configuration, profile and sizes of the connection components could be the suitable approach for the practical design engineers in order to predict the generalized behavior of any SPR BCC. This paper describes the experimental behavior of SPR BCCs tested using a double cantilever test set-up. Eight sets of specimens were identified based on the variation in column thickness, beam depth and number of tabs in the beam end connector in order to investigate the most influential factors affecting the connection performance. Four tests were repeatedly performed for each set to bring uniformity to the results taking the total number of tests to thirty-two. The moment-rotation (M-θ behavior, load-strain relationship, major failure modes and the influence of selected parameters on connection performance were investigated. A comparative study to calculate the connection stiffness was carried out using the initial stiffness method, the slope to half-ultimate moment method and the equal area method. In order to find out the more appropriate method, the mean stiffness of all the tested connections and the variance in values of mean stiffness according to all three methods were calculated. The calculation of connection stiffness by means of the initial stiffness method is considered to overestimate the values when compared to the other two methods. The equal area method provided more consistent values of stiffness and lowest variance in the data set as compared to the other two methods.

  18. Steel Rack Connections: Identification of Most Influential Factors and a Comparison of Stiffness Design Methods

    Science.gov (United States)

    Shah, S. N. R.; Sulong, N. H. Ramli; Shariati, Mahdi; Jumaat, M. Z.

    2015-01-01

    Steel pallet rack (SPR) beam-to-column connections (BCCs) are largely responsible to avoid the sway failure of frames in the down-aisle direction. The overall geometry of beam end connectors commercially used in SPR BCCs is different and does not allow a generalized analytic approach for all types of beam end connectors; however, identifying the effects of the configuration, profile and sizes of the connection components could be the suitable approach for the practical design engineers in order to predict the generalized behavior of any SPR BCC. This paper describes the experimental behavior of SPR BCCs tested using a double cantilever test set-up. Eight sets of specimens were identified based on the variation in column thickness, beam depth and number of tabs in the beam end connector in order to investigate the most influential factors affecting the connection performance. Four tests were repeatedly performed for each set to bring uniformity to the results taking the total number of tests to thirty-two. The moment-rotation (M-θ) behavior, load-strain relationship, major failure modes and the influence of selected parameters on connection performance were investigated. A comparative study to calculate the connection stiffness was carried out using the initial stiffness method, the slope to half-ultimate moment method and the equal area method. In order to find out the more appropriate method, the mean stiffness of all the tested connections and the variance in values of mean stiffness according to all three methods were calculated. The calculation of connection stiffness by means of the initial stiffness method is considered to overestimate the values when compared to the other two methods. The equal area method provided more consistent values of stiffness and lowest variance in the data set as compared to the other two methods. PMID:26452047

  19. Functional connectivity mapping of regions associated with self- and other-processing.

    Science.gov (United States)

    Murray, Ryan J; Debbané, Martin; Fox, Peter T; Bzdok, Danilo; Eickhoff, Simon B

    2015-04-01

    Neuroscience literature increasingly suggests a conceptual self composed of interacting neural regions, rather than independent local activations, yet such claims have yet to be investigated. We, thus, combined task-dependent meta-analytic connectivity modeling (MACM) with task-independent resting-state (RS) connectivity analysis to delineate the neural network of the self, across both states. Given psychological evidence implicating the self's interdependence on social information, we also delineated the neural network underlying conceptual other-processing. To elucidate the relation between the self-/other-networks and their function, we mined the MACM metadata to generate a cognitive-behavioral profile for an empirically identified region specific to conceptual self, the pregenual anterior cingulate (pACC), and conceptual other, posterior cingulate/precuneus (PCC/PC). Mining of 7,200 published, task-dependent, neuroimaging studies, using healthy human subjects, yielded 193 studies activating the self-related seed and were conjoined with RS connectivity analysis to delineate a differentiated self-network composed of the pACC (seed) and anterior insula, relative to other functional connectivity. Additionally, 106 studies activating the other-related seed were conjoined with RS connectivity analysis to delineate a differentiated other-network of PCC/PC (seed) and angular gyrus/temporoparietal junction, relative to self-functional connectivity. The self-network seed related to emotional conflict resolution and motivational processing, whereas the other-network seed related to socially oriented processing and contextual information integration. Notably, our findings revealed shared RS connectivity between ensuing self-/other-networks within the ventromedial prefrontal cortex and medial orbitofrontal cortex, suggesting self-updating via integration of self-relevant social information. We, therefore, present initial neurobiological evidence corroborating the increasing

  20. Aberrant functional connectivity between motor and language networks in rolandic epilepsy.

    Science.gov (United States)

    Besseling, René M H; Overvliet, Geke M; Jansen, Jacobus F A; van der Kruijs, Sylvie J M; Vles, Johannes S H; Ebus, Saskia C M; Hofman, Paul A M; de Louw, Anton J A; Aldenkamp, Albert P; Backes, Walter H

    2013-12-01

    Rolandic epilepsy (RE) is an idiopathic focal childhood epilepsy with a well-established neuropsychological profile of language impairment. The aim of this study is to provide a functional correlate that links rolandic (sensorimotor) pathology to language problems using functional MRI. Twenty-three children with RE (8-14 years old) and 21 matched controls underwent extensive language assessment (Clinical Evaluation of Language Fundamentals). fMRI was performed at rest and using word generation, reading, and finger tapping paradigms. Since no activation group differences were found, regions of interest (ROIs) were defined at pooled (patients and controls combined) activation maxima and in contralateral homotopic cortex, and used to assess language lateralization as well as for a resting-state connectivity analysis. Furthermore, the association between connection strength and language performance was investigated. Reduced language performance was found in the children with RE. Bilateral activation was found for both language tasks with some predominance of the left hemisphere in both groups. Compared to controls, patient connectivity was decreased between the left sensorimotor area and right inferior frontal gyrus (planguage scores in the patient group (r=0.49, p=0.02), but not in the controls. Language laterality analysis revealed bilateral language representation in the age range under study (8-14 years). As a consequence, the connection of reduced functional connectivity we found represents an impaired interplay between motor and language networks, and aberrant functional connectivity associated with poorer language performance. These findings provide a first neuronal correlate in terms of aberrant resting-state functional connectivity for language impairment in RE. Copyright © 2013 Elsevier B.V. All rights reserved.

  1. A qualitative study of laymens' experiences of risk in connection with storage of nuclear waste

    International Nuclear Information System (INIS)

    Karlsson, Gunnar; Ljungberg, Anneli

    1990-12-01

    This study aims at investigating laymens' experiences of risk in connection with storage of nuclear waste. The data consisted of interviews. To begin with, a pilot study was conducted using 14 subjects, with the aim of generating issues that could be further penetrated in the main study. The main study consisted of interviews with 30 subjects. The final data analysis was based on 25 subjects' answers to the interviews, with 5 of the 30 persons omitted due to contradictory and extremely vague answers, making any coherent interpretation impossible. The results section is divided into 3 parts. The first clarifies the conditions for the possibility of experiencing risk. These conditions are so general that they are most likely valid as conditions for any kind of risk experience. The second part of the results section consists of a presentation and clarification of the components which made up the subjects experiences of risk in connection with storage of nuclear waste. The third and final part of the results section consists of a presentation of the two main profiles in the experience of risk in connection with storage of nuclear waste. These two main profiles can be conceived of as opposites. One of the risk profiles was constituted in the following way; a perception of the risk as high, a negative attitude to nuclear energy, presence of emotional expression, distrust towards significant people, an assumption that experts lacked sufficient knowledge and a focusing or widening frame of reference. The other main profile was constituted as follows; a perception of the risk as not high, an absence of emotional expression, trust towards significant people, an assumption that experts possessed sufficient knowledge and a focusing or weighing frame of reference

  2. Sensing the wind profile

    Energy Technology Data Exchange (ETDEWEB)

    Pena, A.

    2009-03-15

    This thesis consists of two parts. The first is a synopsis of the theoretical progress of the study that is based on a number of journal papers. The papers, which constitute the second part of the report, aim to analyze, measure, and model the wind prole in and beyond the surface layer by combining observations from cup anemometers with lidars. The lidar is necessary to extend the measurements on masts at the Horns Rev offshore wind farm and over at land at Hoevsoere, Denmark. Both sensing techniques show a high degree of agreement for wind speed measurements performed at either sites. The wind speed measurements are averaged for several stability conditions and compare well with the surface-layer wind profile. At Hoevsoere, it is sufficient to scale the wind speed with the surface friction velocity, whereas at Horns Rev a new scaling is added, due to the variant roughness length. This new scaling is coupled to wind prole models derived for flow over the sea and tested against the wind proles up to 160 m at Horns Rev. The models, which account for the boundary-layer height in stable conditions, show better agreement with the measurements than compared to the traditional theory. Mixing-length parameterizations for the neutral wind prole compare well with length-scale measurements up to 300 m at Hoevsoere and 950 m at Leipzig. The mixing-length-derived wind proles strongly deviate from the logarithmic wind prole, but agree better with the wind speed measurements. The length-scale measurements are compared to the length scale derived from a spectral analysis performed up to 160 m at Hoevsoere showing high agreement. Mixing-length parameterizations are corrected to account for stability and used to derive wind prole models. These compared better to wind speed measurements up to 300 m at Hoevsoere than the surface-layer wind prole. The boundary-layer height is derived in nearneutral and stable conditions based on turbulent momentum uxes only and in unstable conditions

  3. USGIN ISO metadata profile

    Science.gov (United States)

    Richard, S. M.

    2011-12-01

    The USGIN project has drafted and is using a specification for use of ISO 19115/19/39 metadata, recommendations for simple metadata content, and a proposal for a URI scheme to identify resources using resolvable http URI's(see http://lab.usgin.org/usgin-profiles). The principal target use case is a catalog in which resources can be registered and described by data providers for discovery by users. We are currently using the ESRI Geoportal (Open Source), with configuration files for the USGIN profile. The metadata offered by the catalog must provide sufficient content to guide search engines to locate requested resources, to describe the resource content, provenance, and quality so users can determine if the resource will serve for intended usage, and finally to enable human users and sofware clients to obtain or access the resource. In order to achieve an operational federated catalog system, provisions in the ISO specification must be restricted and usage clarified to reduce the heterogeneity of 'standard' metadata and service implementations such that a single client can search against different catalogs, and the metadata returned by catalogs can be parsed reliably to locate required information. Usage of the complex ISO 19139 XML schema allows for a great deal of structured metadata content, but the heterogenity in approaches to content encoding has hampered development of sophisticated client software that can take advantage of the rich metadata; the lack of such clients in turn reduces motivation for metadata producers to produce content-rich metadata. If the only significant use of the detailed, structured metadata is to format into text for people to read, then the detailed information could be put in free text elements and be just as useful. In order for complex metadata encoding and content to be useful, there must be clear and unambiguous conventions on the encoding that are utilized by the community that wishes to take advantage of advanced metadata

  4. Ethnosocial profile of Tuvans

    Directory of Open Access Journals (Sweden)

    Valeriya S. Kan

    2016-06-01

    Full Text Available The article examines the ethnosocial profile of contemporary Tuvans, with a focus on the dynamics of population change, human environment, self-consciousness, interethnic relations and language command. Our study was based on the official data of the Federal Census and the current statistics we obtained from Tuva territorial branch of the Federal State Statistics Service, as well as on the outcomes of the opinion polls held by a team lead by the author in 2008-2015. Due to traditionally high birth rate, the Tuvan population of Russia continues to grow (243422 in 2002, 263934 in 2010. This is also true for their share in the total population of Russia (0.17% in 2002, 0.19% in 2010. The main features of Tuvan human environment are their compact settlement within the Republic of Tuva (249299, or 95% of overall population, as well as living largely in a monoethnic environment, low level of ethnocultural and linguistic diversity and prevalence of rural population. The share of indigenous population in the region has been steadily increasing (64% in 1989, 77% in 2002, 82% in 2002, while those of other groups have been decreasing over time. The net migration remains negative due to ethnic Russians leaving the socially and economically dysfunctional region. Tuvans account for 92% of rural population, and 73% of the urban. The rural-urban balance in Tuva is shifting towards the latter slower than in the national average. Interethnic relations in the region can be described as stable, with a slight degree of tension. Problems mainly happen on the level of day-to-day communication. The sub-ethnicity of Tojin Tuvans is decreasing in numbers (4435 people in 2002, and 1856 in 2010. We believe the reason lies in the change of self-consciousness which accompanied the complete abandonment of nomadic lifestyle. In the article, we also define and describe the factors which contribute to the reproduction of Tuvan ethnicity, including the policy of the regional

  5. Cerebro-cerebellar connectivity is increased in primary lateral sclerosis.

    Science.gov (United States)

    Meoded, Avner; Morrissette, Arthur E; Katipally, Rohan; Schanz, Olivia; Gotts, Stephen J; Floeter, Mary Kay

    2015-01-01

    Increased functional connectivity in resting state networks was found in several studies of patients with motor neuron disorders, although diffusion tensor imaging studies consistently show loss of white matter integrity. To understand the relationship between structural connectivity and functional connectivity, we examined the structural connections between regions with altered functional connectivity in patients with primary lateral sclerosis (PLS), a long-lived motor neuron disease. Connectivity matrices were constructed from resting state fMRI in 16 PLS patients to identify areas of differing connectivity between patients and healthy controls. Probabilistic fiber tracking was used to examine structural connections between regions of differing connectivity. PLS patients had 12 regions with increased functional connectivity compared to controls, with a predominance of cerebro-cerebellar connections. Increased functional connectivity was strongest between the cerebellum and cortical motor areas and between the cerebellum and frontal and temporal cortex. Fiber tracking detected no difference in connections between regions with increased functional connectivity. We conclude that functional connectivity changes are not strongly based in structural connectivity. Increased functional connectivity may be caused by common inputs, or by reduced selectivity of cortical activation, which could result from loss of intracortical inhibition when cortical afferents are intact.

  6. Observed and model N(h) profiles for the Bulgarian region

    International Nuclear Information System (INIS)

    Pasheva, Ts.; Samardziev, D.

    1984-01-01

    In this paper, combined bottom- and topside ionospheric N(h)-profiles are presented for the Bulgarian region. The profiles were constructed using ground (ionospheric observatories Sofia and Michurin) and satellite (Interkosmos-19) observations. The observatories make quarter-hourly observations in order to connect bottom and upper parts of the N(h) profile, satellite orbits passing rather near to the observatory (zenith distance less than 100 km) are selected. Thus the time difference between ground station and satellite measurement was never more than 7.5 min

  7. Parity and the spin{statistics connection

    Indian Academy of Sciences (India)

    A simple demonstration of the spin-statistics connection for general causal fields is obtained by using the parity operation to exchange spatial coordinates in the scalar product of a locally commuting field operator, evaluated at position x, with the same field operator evaluated at -x, at equal times.

  8. Seychelles Fisheries Connectivity and Transport Pathways

    Science.gov (United States)

    2015-09-30

    1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. Seychelles Fisheries Connectivity and Transport Pathways...overarching goal for the proposed work is to develop predictive capabilities for physical oceanography for the Seychelles region in support of locally...for ocean observations in the Seychelles region that will lead to long-term data collection efforts. In collaboration with local partnerships, we

  9. Quick-Connect, Slow-Disconnect Bolt

    Science.gov (United States)

    Weddendorf, Bruce

    1995-01-01

    Proposed bolt functions similarly to device described in article "Quick-Connect, Slow-Disconnect Nut" (MFS-28833). Bolt installed in standard threaded hole simply by pushing it into hole. Once inserted, bolt withdrawn only by turning it in conventional way.

  10. Offloading IP Flows onto Lambda-Connections

    NARCIS (Netherlands)

    Fioreze, Tiago; Oude Wolbers, Mattijs; van de Meent, R.; Pras, Aiko

    2007-01-01

    Optical networks are capable of switching IP traffic via lambda connections. In this way, big IP flows that overload the regular IP routing level may be moved to the optical level, where they get better Quality of Service (QoS). At the same time, the IP routing level is off-loaded and can serve

  11. Possible connections between hard and soft processes

    International Nuclear Information System (INIS)

    Blankenbecler, R.

    1977-10-01

    Three topics in constituent hadron models are reviewed: the connection between fixed angle and Regge behavior, the validity of the hard scattering expansion and restrictions on the effects of the transverse momentum of constituents, and the x distribution in the fragmentation region at low transverse momentum. 6 figures

  12. Data analysis of event tape and connection

    International Nuclear Information System (INIS)

    Gong Huili

    1995-01-01

    The data analysis on the VAX-11/780 computer is briefly described, the data is from the recorded event tape of JUHU data acquisition system on the PDP-11/44 computer. The connection of the recorded event tapes of the XSYS data acquisition system on VAX computer is also introduced

  13. Privacy and Security in Connected Vehicles Ecosystems

    Directory of Open Access Journals (Sweden)

    Marius POPA

    2017-01-01

    Full Text Available Modern vehicles could not be figured out without Internet connections in order to provide customers a wide range of services in the vehicle: infotainment platforms, third-party support, on-board and online monitor and maintenance, business analytics for car fleets. Exposure of the vehicles to the Internet turns them into targets for viruses, worms, Trojans, DoS and lot of other threats for connected vehicle security. Beside the classic threats of the Internet exposure, other new threats are introduced by the Internet of Things (IoT new technologies that are poor regulated or undefined yet from the security point of view. Also, the large variety of the IoT technologies not being standardized yet contribute to security issues in this area of the automotive industry. This paper provides an overview of the connected vehicle environment, considering the main components of such kind of system and the main security challenges to be considered for building reliable secure online systems for connected vehicles.

  14. Headaches and Hormones: What's the Connection?

    Science.gov (United States)

    Headaches and hormones: What's the connection? Being female has some real health advantages, but not when it comes to headaches — particularly ... a relationship between headaches and hormonal changes. The hormones estrogen (ES-truh-jen) and progesterone (pro-JES- ...

  15. [Pulmonary involvement in connective tissue disease].

    Science.gov (United States)

    Bartosiewicz, Małgorzata

    2016-01-01

    The connective tissue diseases are a variable group of autoimmune mediated disorders characterized by multiorgan damage. Pulmonary complications are common, usually occur after the onset of joint symptoms, but can also be initially presenting complaint. The respiratory system may be involved in all its component: airways, vessels, parenchyma, pleura and respiratory muscles. Lung involvement is an increasing cause of morbidity and mortality in the connective tissue diseases. Clinical course is highly variable - can range from mild to rapidly progressive, some processes are reversible, while others are irreversible. Thus, the identification of reversible disease , and separately progressive disease, are important clinical issues. The frequency, clinical presentation, prognosis and responce to therapy are different, depending on the pattern of involvement as well as on specyfic diagnostic method used to identify it. High- resolution computed tompography plays an important role in identifying patients with respiratory involvement. Pulmonary function tests are a sensitive tool detecting interstitial lung disease. In this article, pulmonary lung involvement accompanying most frequently apperaing connective tissue diseases - rheumatoid arthritis, systemic sclerosis, lupus erythematosus, polymyositis/dermatomyositis, Sjögrens syndrome and mixed connective tissue disaese are reviewed.

  16. Connecting care competencies and culture during disasters

    Science.gov (United States)

    Chhabra, Vivek

    2009-01-01

    Connecting care Competencies and Culture are core fundamentals in responding to disasters. Thick coordination between professionals, communities and agencies in different geographical areas is crucial to the happening of appropriate preparedness and thus efficient response and mitigation of a disaster. In the next few articles, we present diverse examples related to the preparedness and recovery process to adverse disasters across the globe PMID:19561968

  17. Recording technology in contemporary Nigeria: connecting the ...

    African Journals Online (AJOL)

    Recording technology in contemporary Nigeria: connecting the Nigerian ... Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. DOWNLOAD FULL TEXT Open Access DOWNLOAD FULL TEXT ... for themselves in the nation's music recording industry and its performance ...

  18. Cloud connected vehicles : towards new business opportunities

    NARCIS (Netherlands)

    Krivas, A.

    2017-01-01

    In this report, the concept of a cloud connected smart mobility platform is investigated focusing on enabling easy application development and deployment without vendor lock-ins via an open and multi-vendor environment. A prototype of the platform along with a simple cloud application are developed

  19. Student life--When two worlds connect.

    Science.gov (United States)

    Nash, Theresa

    2014-11-11

    The light bulb moment came to me on a train when I met two people living with long-term conditions. It dawned on me that our nursing students could be an amazing resource to connect people who are socially isolated--older people, young people, carers and others--to beautiful spaces.

  20. Mission Connect Mild TBI Translational Research Consortium

    Science.gov (United States)

    2013-08-01

    and covered with dental acrylic . Isoflurane was discontinued; rats were connected to the trauma device and subjected to a mild 1.0-atm fluid-percussion...thought to play roles in the regulation of extracellular concentrations of water, potassium and other ions, and glutamate and other transmitters and

  1. EMPOWERING GIRLS AND CONNECTING PEOPLE THROUGH ...

    African Journals Online (AJOL)

    Mugumbate

    through a school social work intervention and connecting the people ... All students. (638) who attended the intervention workshop constituted the sample for the study. Data was collected through questionnaires administered after a presentation of the “unknown burden” of .... and high expectations of school performance.

  2. Connections between the matching and chromatic polynomials

    Directory of Open Access Journals (Sweden)

    E. J. Farrell

    1992-01-01

    Full Text Available The main results established are (i a connection between the matching and chromatic polynomials and (ii a formula for the matching polynomial of a general complement of a subgraph of a graph. Some deductions on matching and chromatic equivalence and uniqueness are made.

  3. Quantized Abelian principle connections on Lorentzian manifolds

    International Nuclear Information System (INIS)

    Benini, Marco; Schenkel, Alexander

    2013-03-01

    We construct a covariant functor from a category of Abelian principal bundles over globally hyperbolic spacetimes to a category of *-algebras that describes quantized principal connections. We work within an appropriate differential geometric setting by using the bundle of connections and we study the full gauge group, namely the group of vertical principal bundle automorphisms. Properties of our functor are investigated in detail and, similar to earlier works, it is found that due to topological obstructions the locality property of locally covariant quantum field theory is violated. Furthermore, we prove that, for Abelian structure groups containing a nontrivial compact factor, the gauge invariant Borchers- Uhlmann algebra of the vector dual of the bundle of connections is not separating on gauge equivalence classes of principal connections. We introduce a topological generalization of the concept of locally covariant quantum fields. As examples, we construct for the full subcategory of principal U(1)-bundles two natural transformations from singular homology functors to the quantum field theory functor that can be interpreted as the Euler class and the electric charge. In this case we also prove that the electric charges can be consistently set to zero, which yields another quantum field theory functor that satisfies all axioms of locally covariant quantum field theory.

  4. [Applications and connected objects, new perspectives].

    Science.gov (United States)

    Trudelle, Pierre

    2017-11-01

    Applications and connected objects appear promising in the world of wellbeing and health. Often cheap, they offer numerous perspectives for health promotion, in targeted fields or to fulfil 'niche' needs. This growth, extremely fast over the last five years, has also given rise to potential defiance on the part of users. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  5. Association Between Brain Activation and Functional Connectivity.

    Science.gov (United States)

    Tomasi, Dardo; Volkow, Nora D

    2018-04-13

    The origin of the "resting-state" brain activity recorded with functional magnetic resonance imaging (fMRI) is still uncertain. Here we provide evidence for the neurovascular origins of the amplitude of the low-frequency fluctuations (ALFF) and the local functional connectivity density (lFCD) by comparing them with task-induced blood-oxygen level dependent (BOLD) responses, which are considered a proxy for neuronal activation. Using fMRI data for 2 different tasks (Relational and Social) collected by the Human Connectome Project in 426 healthy adults, we show that ALFF and lFCD have linear associations with the BOLD response. This association was significantly attenuated by a novel task signal regression (TSR) procedure, indicating that task performance enhances lFCD and ALFF in activated regions. We also show that lFCD predicts BOLD activation patterns, as was recently shown for other functional connectivity metrics, which corroborates that resting functional connectivity architecture impacts brain activation responses. Thus, our findings indicate a common source for BOLD responses, ALFF and lFCD, which is consistent with the neurovascular origin of local hemodynamic synchrony presumably reflecting coordinated fluctuations in neuronal activity. This study also supports the development of task-evoked functional connectivity density mapping.

  6. Connections, Coherence, and Cognition in Composition.

    Science.gov (United States)

    Goldstein, Elizabeth; Perfetti, Charles

    In a study conducted to show the importance of sentence connections as a way of looking at a writer's cognitive processes, three devices used to achieve coherence in written discourse were compared and proved to be unequally effective. The devices were cohesion (use of a textual reference in a sentence that has an antecedent in a preceding…

  7. Functional connectivity metrics during stroke recovery

    DEFF Research Database (Denmark)

    Yourganov, Grigori; Schmah, Tanya; Small, Steven L.

    2010-01-01

    We explore functional connectivity in nine subjects measured with 1 5T fMRI-BOLD in a longitudinal study of recovery from unilateral stroke affecting the motor area (Small et al, 2002) We found that several measures of complexity of covariance matrices show strong correlations with behavioral mea...

  8. Connecting Libraries and Schools with CLASP.

    Science.gov (United States)

    Del Vecchio, Stephen

    1993-01-01

    Describes the Dewitt Wallace-Reader's Digest Connecting Libraries and Schools Project (CLASP) of the New York Public Library, a cooperative pilot project to encourage reading among children and youth. Sample projects described include summer reading lists, open school night outreach, and outreach to parents. The importance of materials support is…

  9. GOOSE: Semantic search on Internet connected sensors

    NARCIS (Netherlands)

    Schutte, K.; Bomhof, F.W.; Burghouts, G.J.; Diggelen, J. van; Hiemstra, P.; Hof, J. van 't; Kraaij, W.; Pasman, K.H.W.; Smith, A.J.E.; Versloot, C.A.; Wit, J.J. de

    2013-01-01

    More and more sensors are getting Internet connected. Examples are cameras on cell phones, CCTV cameras for traffic control as well as dedicated security and defense sensor systems. Due to the steadily increasing data volume, human exploitation of all this sensor data is impossible for effective

  10. Quantized Abelian principle connections on Lorentzian manifolds

    Energy Technology Data Exchange (ETDEWEB)

    Benini, Marco [Pavia Univ. (Italy); Istituto Nazionale di Fisica Nucleare, Pavia (Italy); Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Dappiaggi, Claudio [Pavia Univ. (Italy); Istituto Nazionale di Fisica Nucleare, Pavia (Italy); Schenkel, Alexander [Bergische Univ., Wuppertal (Germany). Fachgruppe Mathematik

    2013-03-15

    We construct a covariant functor from a category of Abelian principal bundles over globally hyperbolic spacetimes to a category of *-algebras that describes quantized principal connections. We work within an appropriate differential geometric setting by using the bundle of connections and we study the full gauge group, namely the group of vertical principal bundle automorphisms. Properties of our functor are investigated in detail and, similar to earlier works, it is found that due to topological obstructions the locality property of locally covariant quantum field theory is violated. Furthermore, we prove that, for Abelian structure groups containing a nontrivial compact factor, the gauge invariant Borchers- Uhlmann algebra of the vector dual of the bundle of connections is not separating on gauge equivalence classes of principal connections. We introduce a topological generalization of the concept of locally covariant quantum fields. As examples, we construct for the full subcategory of principal U(1)-bundles two natural transformations from singular homology functors to the quantum field theory functor that can be interpreted as the Euler class and the electric charge. In this case we also prove that the electric charges can be consistently set to zero, which yields another quantum field theory functor that satisfies all axioms of locally covariant quantum field theory.

  11. Discerning connectivity from dynamics in climate networks

    Czech Academy of Sciences Publication Activity Database

    Paluš, Milan; Hartman, David; Hlinka, Jaroslav; Vejmelka, Martin

    2011-01-01

    Roč. 18, č. 5 (2011), s. 751-763 ISSN 1023-5809 R&D Projects: GA ČR GCP103/11/J068 Institutional research plan: CEZ:AV0Z10300504 Keywords : complex networks * climate dynamics * connectivity * North Atlantic Oscillation * solar activity Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 1.597, year: 2011

  12. Connecting strangers at a train station

    DEFF Research Database (Denmark)

    Serafin, Stefania; Böttcher, Niels; Pellarin, Lars

    2005-01-01

    In this paper we describe a virtual instrument or a performance space, placed at Høje Tåstrup train station in Denmark, which is meant to establish communicative connections between strangers, by letting users of the system create soundscapes together across the rails. We discuss mapping...

  13. Battery impedance spectroscopy using bidirectional grid connected ...

    Indian Academy of Sciences (India)

    Shimul Kumar Dam

    Keywords. Impedance spectroscopy; grid connection; battery converter; state of charge; health monitoring. 1. Introduction .... the load should be within the safe range of operation specified by the ... A split capacitor damping scheme is adopted here as shown in ...... spectroscopy testing on the Advanced Technology Devel-.

  14. Connectivity planning to address climate change

    Science.gov (United States)

    Tristan A. Nuñez; Joshua J. Lawler; Brad H. McRae; D. John Pierce; Meade B. Krosby; Darren M. Kavanagh; Peter H. Singleton; Joshua J. Tewksbury

    2013-01-01

    As the climate changes, human land use may impede species from tracking areas with suitable climates. Maintaining connectivity between areas of different temperatures could allow organisms to move along temperature gradients and allow species to continue to occupy the same temperature space as the climate warms. We used a coarse-filter approach to identify broad...

  15. Connecting Learning Spaces Using Mobile Technology

    Science.gov (United States)

    Chen, Wenli; Seow, Peter; So, Hyo-Jeong; Toh, Yancy; Looi, Chee-Kit

    2010-01-01

    The use of mobile technology can help extend children's learning spaces and enrich the learning experiences in their everyday lives where they move from one context to another, switching locations, social groups, technologies, and topics. When students have ubiquitous access to mobile devices with full connectivity, the in-situ use of the mobile…

  16. Korean Kimchi Chemistry: A Multicultural Chemistry Connection

    Science.gov (United States)

    Murfin, Brian

    2009-01-01

    Connecting science with different cultures is one way to interest students in science, to relate science to their lives, and at the same time to broaden their horizons in a variety of ways. In the lesson described here, students make kimchi, a delicious and popular Korean dish that can be used to explore many important chemistry concepts,…

  17. Disrupted functional connectivity in adolescent obesity

    Directory of Open Access Journals (Sweden)

    Laura Moreno-Lopez

    2016-01-01

    Conclusions: These findings suggest that adolescent obesity is linked to disrupted functional connectivity in brain networks relevant to maintaining balance between reward, emotional memories and cognitive control. Our findings may contribute to reconceptualization of obesity as a multi-layered brain disorder leading to compromised motivation and control, and provide a biological account to target prevention strategies for adolescent obesity.

  18. Preservice Teachers Connecting Mathematics and Drumming

    Science.gov (United States)

    Marshall, Anne Marie

    2014-01-01

    Increasingly, elementary classroom teachers are being called to teach a myriad of subjects, including visual art, dance, and music. Preservice teachers must be prepared to teach and integrate multiple subjects. To that end, preservice teachers will need experiences in their preparation that help them to see connections across content areas and…

  19. Connective Intelligence for Childhood Mathematics Education

    Science.gov (United States)

    Novo, María-Luisa; Alsina, Ángel; Marbán, José-María; Berciano, Ainhoa

    2017-01-01

    The construction of a connective brain begins at the earliest ages of human development. However, knowledge about individual and collective brains provided so far by research has been rarely incorporated into Maths in Early Childhood classrooms. In spite of that, it is obvious that it is at these ages when the learning of mathematics acts as a…

  20. Management Science, Economics and Finance: A Connection

    NARCIS (Netherlands)

    C-L. Chang (Chia-Lin); M.J. McAleer (Michael); W.-K. Wong (Wing-Keung)

    2016-01-01

    textabstractThis paper provides a brief review of the connecting literature in management science, economics and finance, and discusses some research that is related to the three disciplines. Academics could develop theoretical models and subsequent econometric models to estimate the parameters in

  1. Emotional Connections in Higher Education Marketing

    Science.gov (United States)

    Durkin, Mark; McKenna, Seamas; Cummins, Darryl

    2012-01-01

    Purpose: Through examination of a case study this paper aims to describe a brand re-positioning exercise and explore how an emotionally driven approach to branding can help create meaningful connections with potential undergraduate students and can positively influence choice. Design/methodology/approach: The paper's approach is a case study…

  2. Parallel fuzzy connected image segmentation on GPU

    OpenAIRE

    Zhuge, Ying; Cao, Yong; Udupa, Jayaram K.; Miller, Robert W.

    2011-01-01

    Purpose: Image segmentation techniques using fuzzy connectedness (FC) principles have shown their effectiveness in segmenting a variety of objects in several large applications. However, one challenge in these algorithms has been their excessive computational requirements when processing large image datasets. Nowadays, commodity graphics hardware provides a highly parallel computing environment. In this paper, the authors present a parallel fuzzy connected image segmentation algorithm impleme...

  3. "Scars" connect classical and quantum theory

    CERN Multimedia

    Monteiro, T

    1990-01-01

    Chaotic systems are unstable and extremely sensitive to initial condititions. So far, scientists have been unable to demonstrate that the same kind of behaviour exists in quantum or microscopic systems. New connections have been discovered though between classical and quantum theory. One is the phenomena of 'scars' which cut through the wave function of a particle (1 page).

  4. Finite Element analysis of jar connections

    DEFF Research Database (Denmark)

    Kristensen, A.; Toor, Kashif; Solem, Sigurd

    2005-01-01

    A new tool joint system is considered. Traditionally these rotary connections have been designed with only one shoulder geometry. However, in order to increase the torque rating of the tool joint, a new design is introduced using two shoulders. This design allow reduced tool joint dimensions...

  5. Connected feedback vertex set in planar graphs

    NARCIS (Netherlands)

    Grigoriev, Alexander; Sitters, René

    2010-01-01

    We study the problem of finding a minimum tree spanning the faces of a given planar graph. We show that a constant factor approximation follows from the unconnected version if the minimum degree is 3. Moreover, we present a polynomial time approximation scheme for both the connected and unconnected

  6. An interoperable security framework for connected healthcare

    NARCIS (Netherlands)

    Asim, M.; Petkovic, M.; Qu, M.; Wang, Changjie

    2011-01-01

    Connected and interoperable healthcare system promises to reduce the cost of healthcare delivery, increase its efficiency and enable consumers to better engage with clinicians and manage their care. However at the same time it introduces new risks towards security and privacy of personal health

  7. An Interoperable Security Framework for Connected Healthcare

    NARCIS (Netherlands)

    Asim, M.; Petkovic, M.; Qu, M.; Wang, C.

    2011-01-01

    Connected and interoperable healthcare system promises to reduce thecost of the healthcare delivery, increase its efficiency and enableconsumers to better engage with clinicians and manage their care. However at the same time it introduces new risks towards security andprivacy of personal health

  8. Precentral gyrus functional connectivity signatures of autism

    Directory of Open Access Journals (Sweden)

    Mary Beth eNebel

    2014-05-01

    Full Text Available Motor impairments are prevalent in children with autism spectrum disorders (ASD and are perhaps the earliest symptoms to develop. In addition, motor skills relate to the communicative/social deficits at the core of ASD diagnosis, and these behavioral deficits may reflect abnormal connectivity within brain networks underlying motor control and learning. Despite the fact that motor abnormalities in ASD are well-characterized, there remains a fundamental disconnect between the complexity of the clinical presentation of ASD and the underlying neurobiological mechanisms. In this study, we examined connectivity within and between functional subregions of a key component of the motor control network, the precentral gyrus, using resting state functional Magnetic Resonance Imaging data collected from a large, heterogeneous sample of individuals with ASD as well as neurotypical controls. We found that the strength of connectivity within and between distinct functional subregions of the precentral gyrus was related to ASD diagnosis and to the severity of ASD traits. In particular, connectivity involving the dorsomedial (lower limb/trunk subregion was abnormal in ASD individuals as predicted by models using a dichotomous variable coding for the presence of ASD, as well as models using symptom severity ratings. These findings provide further support for a link between motor and social/communicative abilities in ASD.

  9. Complexity, Connections, and Soul-Work

    Science.gov (United States)

    Bloch, Deborah P.

    2008-01-01

    Organizational theory and personal behaviors are both shaped by contemporary thinking and theories regarding spirituality, history, and the order, shape, and direction of modern culture. Complexity theory, discussed in this article, offers some helpful insights into appreciating the relationships and connections often overlooked in today's…

  10. Literacy and Sexuality: What's the Connection?

    Science.gov (United States)

    Ashcraft, Catherine

    2009-01-01

    In this column, the author highlights how the current framing of teen sexuality obscures important connections between literacy and sexuality. She argues that we need to challenge two current assumptions: the assumption that teen sexuality is primarily about public health and the assumption that all efforts to address teen sexuality are…

  11. Modeling investor optimism with fuzzy connectives

    NARCIS (Netherlands)

    Lovric, M.; Almeida, R.J.; Kaymak, U.; Spronk, J.; Carvalho, J.P.; Dubois, D.; Kaymak, U.; Sousa, J.M.C.

    2009-01-01

    Optimism or pessimism of investors is one of the important characteristics that determine the investment behavior in financial markets. In this paper, we propose a model of investor optimism based on a fuzzy connective. The advantage of the proposed approach is that the influence of different levels

  12. Hierarchical multivariate covariance analysis of metabolic connectivity.

    Science.gov (United States)

    Carbonell, Felix; Charil, Arnaud; Zijdenbos, Alex P; Evans, Alan C; Bedell, Barry J

    2014-12-01

    Conventional brain connectivity analysis is typically based on the assessment of interregional correlations. Given that correlation coefficients are derived from both covariance and variance, group differences in covariance may be obscured by differences in the variance terms. To facilitate a comprehensive assessment of connectivity, we propose a unified statistical framework that interrogates the individual terms of the correlation coefficient. We have evaluated the utility of this method for metabolic connectivity analysis using [18F]2-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) study. As an illustrative example of the utility of this approach, we examined metabolic connectivity in angular gyrus and precuneus seed regions of mild cognitive impairment (MCI) subjects with low and high β-amyloid burdens. This new multivariate method allowed us to identify alterations in the metabolic connectome, which would not have been detected using classic seed-based correlation analysis. Ultimately, this novel approach should be extensible to brain network analysis and broadly applicable to other imaging modalities, such as functional magnetic resonance imaging (MRI).

  13. Structural connectivity asymmetry in the neonatal brain.

    Science.gov (United States)

    Ratnarajah, Nagulan; Rifkin-Graboi, Anne; Fortier, Marielle V; Chong, Yap Seng; Kwek, Kenneth; Saw, Seang-Mei; Godfrey, Keith M; Gluckman, Peter D; Meaney, Michael J; Qiu, Anqi

    2013-07-15

    Asymmetry of the neonatal brain is not yet understood at the level of structural connectivity. We utilized DTI deterministic tractography and structural network analysis based on graph theory to determine the pattern of structural connectivity asymmetry in 124 normal neonates. We tracted white matter axonal pathways characterizing interregional connections among brain regions and inferred asymmetry in left and right anatomical network properties. Our findings revealed that in neonates, small-world characteristics were exhibited, but did not differ between the two hemispheres, suggesting that neighboring brain regions connect tightly with each other, and that one region is only a few paths away from any other region within each hemisphere. Moreover, the neonatal brain showed greater structural efficiency in the left hemisphere than that in the right. In neonates, brain regions involved in motor, language, and memory functions play crucial roles in efficient communication in the left hemisphere, while brain regions involved in emotional processes play crucial roles in efficient communication in the right hemisphere. These findings suggest that even at birth, the topology of each cerebral hemisphere is organized in an efficient and compact manner that maps onto asymmetric functional specializations seen in adults, implying lateralized brain functions in infancy. Copyright © 2013 Elsevier Inc. All rights reserved.

  14. Dynamic functional brain connectivity for face perception

    NARCIS (Netherlands)

    Yang, Yuan; Qiu, Yihong; Schouten, Alfred C.

    2015-01-01

    Face perception is mediated by a distributed brain network comprised of the core system at occipito-temporal areas and the extended system at other relevant brain areas involving bilateral hemispheres. In this study we explored how the brain connectivity changes over the time for face-sensitive

  15. Formal truncations of connected kernel equations

    International Nuclear Information System (INIS)

    Dixon, R.M.

    1977-01-01

    The Connected Kernel Equations (CKE) of Alt, Grassberger and Sandhas (AGS); Kouri, Levin and Tobocman (KLT); and Bencze, Redish and Sloan (BRS) are compared against reaction theory criteria after formal channel space and/or operator truncations have been introduced. The Channel Coupling Class concept is used to study the structure of these CKE's. The related wave function formalism of Sandhas, of L'Huillier, Redish and Tandy and of Kouri, Krueger and Levin are also presented. New N-body connected kernel equations which are generalizations of the Lovelace three-body equations are derived. A method for systematically constructing fewer body models from the N-body BRS and generalized Lovelace (GL) equations is developed. The formally truncated AGS, BRS, KLT and GL equations are analyzed by employing the criteria of reciprocity and two-cluster unitarity. Reciprocity considerations suggest that formal truncations of BRS, KLT and GL equations can lead to reciprocity-violating results. This study suggests that atomic problems should employ three-cluster connected truncations and that the two-cluster connected truncations should be a useful starting point for nuclear systems

  16. Existence and Stability of Viscous Shock Profiles for 2-D Isentropic MHD with Infinite Electrical Resistivity

    International Nuclear Information System (INIS)

    Blake, B.; Zumbrun, K.; Lafitte, O.

    2010-01-01

    For the two-dimensional Navier Stokes equations of isentropic magnetohydrodynamics (MHD) with γ-law gas equation of state, γ≥1, and infinite electrical resistivity, we carry out a global analysis categorizing all possible viscous shock profiles. Precisely, we show that the phase portrait of the Crave ling-wave ODE generically consists of either two rest points connected by a viscous Lax profile, or else four rest points, two saddles and two nodes. In the latter configuration, which rest points are connected by profiles depends on the ratio of viscosities, and can involve Lax, over-compressive, or under-compressive shock profiles. Considered as three-dimensional solutions, under-compressive shocks are Lax-type (Alfven) waves. For the monatomic and diatomic cases γ=5/3 and γ=7/5, with standard viscosity ratio for a nonmagnetic gas, we find numerically that the the nodes are connected by a family of over-compressive profiles bounded by Lax profiles connecting saddles to nodes, with no under-compressive shocks occurring. We carry out a systematic numerical Evans function analysis indicating that all of these two-dimensional shock profiles are linearly and nonlinearly stable, both with respect to two- and three-dimensional perturbations. For the same gas constants, but different viscosity ratios, we investigate also cases for which under-compressive shocks appear; these are seen numerically to be stable as well, both with respect to two-dimensional and (in the neutral sense of convergence to nearby Riemann solutions) three-dimensional perturbations. (authors)

  17. The connection of time perspective with personality traits and subjective well-being

    Directory of Open Access Journals (Sweden)

    Tina Podlogar

    2011-04-01

    Full Text Available The aim of our study was to research the connection of the six time perspective dimensions and of balanced time perspective with personality traits and subjective well-being. Our starting point was the assumption that time perspective is closely connected to personality traits and subjective well-being. It has been theorized that so called balanced time perspective is optimal in the Western cultures. It is defined by moderately high scores on present-hedonistic and future, high scores on past-positive and low scores on past-negative and present-fatalistic, with an emphasis on individual's ability of flexible adjusting in given situations. People with balanced time perspective profile have many positive memories of the past, find enough opportunity for relaxation and pleasure in the present, and seek new challenges in the future, which gives them motivation for hard work. They are supposed to handle daily life more efficiently and to be happier than people with other time perspective profiles. Therefore we have hypothesized positive connection of balanced time perspective with positive personality traits and high scores on subjective well-being. 279 students studying different subjects at the Faculty of arts, University in Ljubljana, whose mean age was 21.2 years, participated in the study. The results reveal connections of positive time perspective dimensions (including transcendental-future and of balanced time perspective with extraversion, agreeableness, conscientiousness and higher level of subjective well-being, and connections of negative time perspective dimensions with neuroticism, lower level of subjective well-being and higher level of depression. It turned out that balance of time perspective is an important predictor of individual's level of satisfaction with life, and it also explains some variance in positive emotionality and depression.

  18. [Profile of silodosin].

    Science.gov (United States)

    Montorsi, Francesco

    2013-01-01

    Silodosin is a highly selective alpha1A-adrenoceptor antagonist approved for the treatment of the signs and symptoms of benign prostatic hyperplasia. Its clinical pharmacology profile offers a number of advantages, including uroselectivity, once-daily (QD) dosing, a standard dose of 8 mg QD that does not need to be adjusted according to age, and the feasibility of concomitant treatment with phosphodiesterase type 5 (PDE5) inhibitors and antihypertensive agents. Three phase 3 double-blind, randomised trials using the dosage regimen of 8 mg QD in > 800 patients have shown that silodosin is significantly more effective than placebo (p nocturia (p = 0.03). Safety data collected in 1581 patients exposed to chronic treatment with silodosin 8 mg QD have shown that the drug is safe and well tolerated. As was to be expected with a uroselective compound, cardiovascular effects have been minimal. The most common adverse reaction is "retrograde ejaculation" (anejaculation), which led to treatment discontinuation in only 3.9% of patients. The rare, drug class-related safety issue of intraocular floppy iris syndrome can be satisfactorily managed by warning patients simply to inform their ophthalmologist that they are or were on treatment with an alpha1-adrenoceptor blocker.

  19. Aliskiren: a clinical profile

    Directory of Open Access Journals (Sweden)

    Roland E Schmieder

    2006-06-01

    Full Text Available Aliskiren is a novel oral antihypertensive agent, and the first in the new class of direct renin inhibitors. Here we review the key criteria that a new antihypertensive drug should possess, notably effective blood pressure lowering as monotherapy and combination therapy, 24-hour blood pressure control, safety and tolerability, end-organ protective effects, minimal drug interaction and efficacy during long-term use.Aliskiren fulfils key criteria for a new antihypertensive agent.The drug demonstrates effective blood lowering in a number of studies as monotherapy and in combination with a thiazide diuretic (hydrochlorothiazide, an angiotensin-converting enzyme inhibitor (ramipril and a calcium channel blocker (amlodipine. Other studies applying ambulatory blood pressure monitoring show that aliskiren maintains blood pressure control for more than 24 hours. Aliskiren, 150 mg and 300 mg have demonstrated a placebo-like safety and tolerability profile, with no interactions with a wide range of commonly used drugs. Three studies (AVOID, ALOFT and ALLAY are ongoing properties. with aliskiren to assess end-organ protective properties.

  20. The worker profile autocontrolled

    Directory of Open Access Journals (Sweden)

    Jairo Omar Delgado Mora

    2015-06-01

    Full Text Available This document is part of two deliveries. In this first paper is to make an approach to the concept of self-control from the very beginning with Sakichi Toyoda, founder of what the industry Toyota Motor Company, additionally taking some excerpts of the concept issued by teachers and the psychologist Henry Murray, a professor at the university Harvard precursor test TAT personality test creator, pen applied world wide by psychologists David McCllelan, also a psychologist and a pioneer in the study of human needs and the concept of competence; Professor Jeffrey Pfeffer of Stanford University organizational behavior and theory, Frederick Hertzberg, Psychologist and strong influential in business management, Kronfly Cruz, lawyer and investigator of social and administrative sciences, Charles Perrow, a sociologist at Yale University and Stanford , who studies the impact of large organizations in society, among others. The study reflects the need to meet organizational objectives related to the physicochemical characteristics of the finished product in a plant of the company’s main beers in the country. In this paper, we intend to make an approximation of worker self -controlled, which when compared with the powers, generic, specific and technical area established by the brewery, will allow generating a methodology to adjust these competencies and to obtain the target profile drawn. This comparison and development of the methodology proposed is the subject of the second work planned.