WorldWideScience

Sample records for rita electronic resource

  1. Mineral, Energy, and Fertilizer Resources of the North Coast of Peru: Perspective from the Santa Rita B Archaeological Site

    Science.gov (United States)

    Brooks, William E.; Kent, Jonathan D.; Willett, Jason C.

    2004-01-01

    The Santa Rita B archaeological site is in the Chao Valley, approximately 65 km southeast of Trujillo, northern Peru. Location of Santa Rita B at the emergence of several drainages from the Andean cordillera is an important factor in the almost continuous occupation of the site over the past 3,000 years. Mineral resources are abundant throughout the Andes; however, the north coast of Peru was an important center for pre-Columbian mining, metallurgy, and craftsmanship. Success of the Chavin, Moche, Chimu, and other north coast cultures is directly related to the availability and exploitation of mineral and energy resources that include: gold (?silver), as electrum, mainly from placers, and copper from local oxide and carbonate occurrences and from sulfides related to copper porphyry occurrences in the cordillera. An alloy of these three metals is referred to as tumbaga, which is the primary material for Andean metalcraft. Anthracite was used for mirrors by north coast cultures and is available near Rio Chicama, Rio Santa, and east of Santa Rita B. These outcrops are a part of the Alto Chicama, Peru's largest coalfield, which extends from Rio Chicama, in the north, for 200 km southward to Rio Santa. Charcoal from the algorrobo tree and llama dung are considered to be the common pre-Columbian energy sources for cooking and metalwork; however, availability and the higher heat content of anthracite indicate that it was used in metallurgical applications. Bitumen is available from petroleum seeps near Talara, north of the study area, and may have been used as glue or as cement. Hematite, goethite, limonite, and manganese oxides from clay-altered volcanic rock may have provided color and material for ceramics. Guano from the Islas Gua?apes, Chinchas, and Ballestas was used as fertilizer for cotton and other crops.

  2. Electronic Resource Management Systems

    Directory of Open Access Journals (Sweden)

    Mark Ellingsen

    2004-10-01

    Full Text Available Computer applications which deal with electronic resource management (ERM are quite a recent development. They have grown out of the need to manage the burgeoning number of electronic resources particularly electronic journals. Typically, in the early years of e-journal acquisition, library staff provided an easy means of accessing these journals by providing an alphabetical list on a web page. Some went as far as categorising the e-journals by subject and then grouping the journals either on a single web page or by using multiple pages. It didn't take long before it was recognised that it would be more efficient to dynamically generate the pages from a database rather than to continually edit the pages manually. Of course, once the descriptive metadata for an electronic journal was held within a database the next logical step was to provide administrative forms whereby that metadata could be manipulated. This in turn led to demands for incorporating more information and more functionality into the developing application.

  3. Electronic Resource Management and Design

    Science.gov (United States)

    Abrams, Kimberly R.

    2015-01-01

    We have now reached a tipping point at which electronic resources comprise more than half of academic library budgets. Because of the increasing work associated with the ever-increasing number of e-resources, there is a trend to distribute work throughout the library even in the presence of an electronic resources department. In 2013, the author…

  4. Til lykke eller Rita

    DEFF Research Database (Denmark)

    Agger, Gunhild

    2012-01-01

    Med Rita og Lykke har den satiriske sædekomedie fået en renæssance. Sædekomedien lever af at udstille normbrud og satirisere over menneskenes omgangsformer og kommunikation eller mangel på samme. Det er netop det, der sker i Rita og Lykke, hvor det outrerede eksponeres for at latterliggøres....

  5. A Green Prison: The Santa Rita Jail Campus Microgrid

    Energy Technology Data Exchange (ETDEWEB)

    Marnay, Chris; DeForest, Nicholas; Lai, Judy

    2012-01-22

    A large microgrid project is nearing completion at Alameda County’s twenty-two-year-old 45 ha 4,000-inmate Santa Rita Jail, about 70 km east of San Francisco. Often described as a green prison, it has a considerable installed base of distributed energy resources (DER) including an eight-year old 1.2 MW PV array, a five-year old 1 MW fuel cell with heat recovery, and considerable efficiency investments. A current US$14 M expansion adds a 2 MW-4 MWh Li-ion battery, a static disconnect switch, and various controls upgrades. During grid blackouts, or when conditions favor it, the Jail can now disconnect from the grid and operate as an island, using the on-site resources described together with its back-up diesel generators. In other words, the Santa Rita Jail is a true microgrid, or μgrid, because it fills both requirements, i.e. it is a locally controlled system, and it can operate both grid connected and islanded. The battery’s electronics includes Consortium for Electric Reliability Technology (CERTS) Microgrid technology. This enables the battery to maintain energy balance using droops without need for a fast control system.

  6. Managing electronic resources a LITA guide

    CERN Document Server

    Weir, Ryan O

    2012-01-01

    Informative, useful, current, Managing Electronic Resources: A LITA Guide shows how to successfully manage time, resources, and relationships with vendors and staff to ensure personal, professional, and institutional success.

  7. Rita Bottoms: Polyartist Librarian

    OpenAIRE

    Bottoms, Rita; Reti, Irene; Regional History Project, UCSC Library

    2005-01-01

    Project Director Irene Reti conducted fourteen hours of interviews with Rita Bottoms, Head of Special Collections at the University Library, UC Santa Cruz, shortly before her retirement in March 2003. This oral history provides a vivid and intimate look at thirty-seven years behind the scenes in the library's Special Collections. For thirty-seven years Bottoms dedicated herself to collecting work by some of the most eminent writers and photographers of the twentieth century, includin...

  8. Ang Rita 1

    OpenAIRE

    Loomis, Molly

    2012-01-01

    .wav and .mp3 versions of audio file Ang Rita describes in Sherpa difference aspects of his life as a yak herder and yak herding culture. Tape includes native names for yak, birth and death ceremonies; castration practices; differences between Sherpa and Tibetan customs regarding yaks; herding yaks as a child; herding calls; interactions with wolves; grazing practices; concerns about decline of yak herding and the environmental consequences; the future of yak herding; famous yak herders; t...

  9. Interview: Rita Colwell

    OpenAIRE

    Alucozai, Milad

    2012-01-01

    Dr. Rita Colwell is a renowned microbiologist and infectious disease expert as well as a Purdue Alumna. She served as the 11th director of the National Science Foundation (NSF) from 1998 to 2004. Currently, she serves as the President and CEO of CosmosID and is a Distinguished Professor at both the University of Maryland and Johns Hopkins University School of Public Health.

  10. Electronic Resources Management Project Presentation 2012

    KAUST Repository

    Ramli, Rindra M.

    2012-11-05

    This presentation describes the electronic resources management project undertaken by the KAUST library. The objectives of this project is to migrate information from MS Sharepoint to Millennium ERM module. One of the advantages of this migration is to consolidate all electronic resources into a single and centralized location. This would allow for better information sharing among library staff.

  11. Implementing CORAL: An Electronic Resource Management System

    Science.gov (United States)

    Whitfield, Sharon

    2011-01-01

    A 2010 electronic resource management survey conducted by Maria Collins of North Carolina State University and Jill E. Grogg of University of Alabama Libraries found that the top six electronic resources management priorities included workflow management, communications management, license management, statistics management, administrative…

  12. Electronic Resources Management System: Recommendation Report 2017

    KAUST Repository

    Ramli, Rindra M.

    2017-01-01

    This recommendation report provides an overview of the selection process for the new Electronic Resources Management System. The library has decided to move away from Innovative Interfaces Millennium ERM module. The library reviewed 3 system

  13. Electronic Resources Management Project Presentation 2012

    KAUST Repository

    Ramli, Rindra M.

    2012-01-01

    This presentation describes the electronic resources management project undertaken by the KAUST library. The objectives of this project is to migrate information from MS Sharepoint to Millennium ERM module. One of the advantages of this migration

  14. PRINCIPLES OF CONTENT FORMATION EDUCATIONAL ELECTRONIC RESOURCE

    Directory of Open Access Journals (Sweden)

    О Ю Заславская

    2017-12-01

    Full Text Available The article considers modern possibilities of information and communication technologies for the design of electronic educational resources. The conceptual basis of the open educational multimedia system is based on the modular architecture of the electronic educational resource. The content of the electronic training module can be implemented in several versions of the modules: obtaining information, practical exercises, control. The regularities in the teaching process in modern pedagogical theory are considered: general and specific, and the principles for the formation of the content of instruction at different levels are defined, based on the formulated regularities. On the basis of the analysis, the principles of the formation of the electronic educational resource are determined, taking into account the general and didactic patterns of teaching.As principles of the formation of educational material for obtaining information for the electronic educational resource, the article considers: the principle of methodological orientation, the principle of general scientific orientation, the principle of systemic nature, the principle of fundamentalization, the principle of accounting intersubject communications, the principle of minimization. The principles of the formation of the electronic training module of practical studies in the article include: the principle of systematic and dose based consistency, the principle of rational use of study time, the principle of accessibility. The principles of the formation of the module for monitoring the electronic educational resource can be: the principle of the operationalization of goals, the principle of unified identification diagnosis.

  15. Electronic Resources Management System: Recommendation Report 2017

    KAUST Repository

    Ramli, Rindra M.

    2017-05-01

    This recommendation report provides an overview of the selection process for the new Electronic Resources Management System. The library has decided to move away from Innovative Interfaces Millennium ERM module. The library reviewed 3 system as potential replacements namely: Proquest 360 Resource Manager, Ex Libris Alma and Open Source CORAL ERMS. After comparing and trialling the systems, it was decided to go for Proquest 360 Resource Manager.

  16. CHALLENGES OF ELECTRONIC INFORMATION RESOURCES IN ...

    African Journals Online (AJOL)

    This paper discusses the role of policy for proper and efficient library services in the electronic era. It points out some of the possible dangers of embarking in electronic resources without a proper focus at hand. Thus, it calls for today's librarians and policy makers to brainstorm and come up with working policies suitable to ...

  17. Hurricane Rita Poster (September 22, 2005)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Hurricane Rita poster. Multi-spectral image from NOAA-16 shows Hurricane Rita as a category-4 hurricane in the Gulf of Mexico on September 22, 2005. Poster size is...

  18. Library training to promote electronic resource usage

    DEFF Research Database (Denmark)

    Frandsen, Tove Faber; Tibyampansha, Dativa; Ibrahim, Glory

    2017-01-01

    Purpose: Increasing the usage of electronic resources is an issue of concern for many libraries all over the world. Several studies stress the importance of information literacy and instruction in order to increase the usage. Design/methodology/approach: The present article presents the results...

  19. Proteomic profiling of white muscle from freshwater catfish Rita rita.

    Science.gov (United States)

    Mohanty, Bimal Prasanna; Mitra, Tandrima; Banerjee, Sudeshna; Bhattacharjee, Soma; Mahanty, Arabinda; Ganguly, Satabdi; Purohit, Gopal Krishna; Karunakaran, Dhanasekar; Mohanty, Sasmita

    2015-06-01

    Muscle tissues contribute 34-48 % of the total body mass in fish. Proteomic analysis enables better understanding of the skeletal muscle physiology and metabolism. A proteome map reflects the general fingerprinting of the fish species and has the potential to identify novel proteins which could serve as biomarkers for many aspects of aquaculture including fish physiology and growth, flesh quality, food safety and aquatic environmental monitoring. The freshwater catfish Rita rita of the family Bagridae inhabiting the tropical rivers and estuaries is an important food fish with high nutritive value and is also considered a species of choice in riverine pollution monitoring. Omics information that could enhance utility of this species in molecular research is meager. Therefore, in the present study, proteomic analysis of Rita rita muscle has been carried out and functional genomics data have been generated. A reference muscle proteome has been developed, and 23 protein spots, representing 18 proteins, have been identified by MALDI-TOF/TOF-MS and LC-MS/MS. Besides, transcript information on a battery of heat shock proteins (Hsps) has been generated. The functional genomics information generated could act as the baseline data for further molecular research on this species.

  20. Chk2 mediates RITA-induced apoptosis.

    Science.gov (United States)

    de Lange, J; Verlaan-de Vries, M; Teunisse, A F A S; Jochemsen, A G

    2012-06-01

    Reactivation of the p53 tumor-suppressor protein by small molecules like Nutlin-3 and RITA (reactivation of p53 and induction of tumor cell apoptosis) is a promising strategy for cancer therapy. The molecular mechanisms involved in the responses to RITA remain enigmatic. Several groups reported the induction of a p53-dependent DNA damage response. Furthermore, the existence of a p53-dependent S-phase checkpoint has been suggested, involving the checkpoint kinase Chk1. We have recently shown synergistic induction of apoptosis by RITA in combination with Nutlin-3, and we observed concomitant Chk2 phosphorylation. Therefore, we investigated whether Chk2 contributes to the cellular responses to RITA. Strikingly, the induction of apoptosis seemed entirely Chk2 dependent. Transcriptional activity of p53 in response to RITA required the presence of Chk2. A partial rescue of apoptosis observed in Noxa knockdown cells emphasized the relevance of p53 transcriptional activity for RITA-induced apoptosis. In addition, we observed an early p53- and Chk2-dependent block of DNA replication upon RITA treatment. Replicating cells seemed more prone to entering RITA-induced apoptosis. Furthermore, the RITA-induced DNA damage response, which was not a secondary effect of apoptosis induction, was strongly attenuated in cells lacking p53 or Chk2. In conclusion, we identified Chk2 as an essential mediator of the cellular responses to RITA.

  1. Electronic resource management systems a workflow approach

    CERN Document Server

    Anderson, Elsa K

    2014-01-01

    To get to the bottom of a successful approach to Electronic Resource Management (ERM), Anderson interviewed staff at 11 institutions about their ERM implementations. Among her conclusions, presented in this issue of Library Technology Reports, is that grasping the intricacies of your workflow-analyzing each step to reveal the gaps and problems-at the beginning is crucial to selecting and implementing an ERM. Whether the system will be used to fill a gap, aggregate critical data, or replace a tedious manual process, the best solution for your library depends on factors such as your current soft

  2. use of electronic resources by graduate students of the department

    African Journals Online (AJOL)

    respondent's access electronic resources from the internet via Cybercafé .There is a high ... KEY WORDS: Use, Electronic Resources, Graduate Students, Cybercafé. INTRODUCTION ... Faculty of Education, University of Uyo, Uyo. Olu Olat ...

  3. 27 CFR 9.162 - Sta. Rita Hills.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Sta. Rita Hills. 9.162.... Rita Hills. (a) Name. The name of the viticultural area described in this section is “Sta. Rita Hills”. For purposes of part 4 of this chapter, “Sta. Rita Hills” is a term of viticultural significance. (b...

  4. RITA-type triple axis spectrometers

    International Nuclear Information System (INIS)

    Roennow, H.M.

    2001-01-01

    The RITA spectrometer at Risoe National Laboratory was the first to incorporate a complete re-thinking of the neutron-path from source, through detector to analysis. Since then, other RITA-type spectrometers such as SPINS at NIST, RITA-II at PSI have been built, and several new spectrometers around the world are adapting the same philosophy. The main novelty of RITA was the introduction of a single back-end tank featuring both an analyser block with multiple individually turnable analyser blades and a 2D position sensitive detector. Several new triple-axis spectrometers are presently being built at existing and future sources, and almost all of them have learnt from the experience with RITA. (R.P.)

  5. Use of Electronic Resources in a Private University in Nigeria ...

    African Journals Online (AJOL)

    The study examined awareness and constraints in the use of electronic resources by lecturers and students of Ajayi Crowther University, Oyo, Nigeria. It aimed at justifying the resources expended in the provision of electronic resources in terms of awareness, patronage and factors that may be affecting awareness and use ...

  6. Gender Analysis Of Electronic Information Resource Use: The Case ...

    African Journals Online (AJOL)

    Based on the findings the study concluded that access and use of electronic information resources creates a “social digital divide” along gender lines. The study ... Finally, the library needs to change its marketing strategies on the availability of electronic information resources to increase awareness of these resources.

  7. Electronic Resource Management System. Vernetzung von Lizenzinformationen

    Directory of Open Access Journals (Sweden)

    Michaela Selbach

    2014-12-01

    Full Text Available In den letzten zehn Jahren spielen elektronische Ressourcen im Bereich der Erwerbung eine zunehmend wichtige Rolle: Eindeutig lässt sich hier ein Wandel in den Bibliotheken (fort vom reinen Printbestand zu immer größeren E-Only-Beständen feststellen. Die stetig wachsende Menge an E-Ressourcen und deren Heterogenität stellt Bibliotheken vor die Herausforderung, die E-Ressourcen effizient zu verwalten. Nicht nur Bibliotheken, sondern auch verhandlungsführende Institutionen von Konsortial- und Allianzlizenzen benötigen ein geeignetes Instrument zur Verwaltung von Lizenzinformationen, welches den komplexen Anforderungen moderner E-Ressourcen gerecht wird. Die Deutsche Forschungsgemeinschaft (DFG unterstützt ein Projekt des Hochschulbibliothekszentrums des Landes Nordrhein-Westfalen (hbz, der Universitätsbibliothek Freiburg, der Verbundzentrale des Gemeinsamen Bibliotheksverbundes (GBV und der Universitätsbibliothek Frankfurt, in dem ein bundesweit verfügbares Electronic Ressource Managementsystem (ERMS aufgebaut werden soll. Ein solches ERMS soll auf Basis einer zentralen Knowledge Base eine einheitliche Nutzung von Daten zur Lizenzverwaltung elektronischer Ressourcen auf lokaler, regionaler und nationaler Ebene ermöglichen. Statistische Auswertungen, Rechteverwaltung für alle angeschlossenen Bibliotheken, kooperative Datenpflege sowie ein über standardisierte Schnittstellen geführter Datenaustausch stehen bei der Erarbeitung der Anforderungen ebenso im Fokus wie die Entwicklung eines Daten- und Funktionsmodells. In the last few years the importance of electronic resources in library acquisitions has increased significantly. There has been a shift from mere print holdings to both e- and print combinations and even e-only subscriptions. This shift poses a double challenge for libraries: On the one hand they have to provide their e-resource collections to library users in an appealing way, on the other hand they have to manage these

  8. Electronic human resource management: Enhancing or entrancing?

    Directory of Open Access Journals (Sweden)

    Paul Poisat

    2017-07-01

    Full Text Available Orientation: This article provides an investigation into the current level of development of the body of knowledge related to electronic human resource management (e-HRM by means of a qualitative content analysis. Several aspects of e-HRM, namely definitions of e-HRM, the theoretical perspectives around e-HRM, the role of e-HRM, the various types of e-HRM and the requirements for successful e-HRM, are examined. Research purpose: The purpose of the article was to determine the status of e-HRM and examine the studies that report on the link between e-HRM and organisational productivity. Motivation for the study: e-HRM has the capacity to improve organisational efficiency and leverage the role of human resources (HR as a strategic business partner. Main findings: The notion that the implementation of e-HRM will lead to improved organisational productivity is commonly assumed; however, empirical evidence in this regard was found to be limited. Practical/managerial implications: From the results of this investigation it is evident that more research is required to gain a greater understanding of the influence of e-HRM on organisational productivity, as well as to develop measures for assessing this influence. Contribution: This article proposes additional areas to research and measure when investigating the effectiveness of e-HRM. It provides a different lens from which to view e-HRM assessment whilst keeping it within recognised HR measurement parameters (the HR value chain. In addition, it not only provides areas for measuring e-HRM’s influence but also provides important clues as to how the measurements may be approached.

  9. Utilization of electronic information resources by academic staff at ...

    African Journals Online (AJOL)

    The study investigated the utilization of Electronic Information resources by the academic staff of Makerere University in Uganda. It examined the academic staff awareness of the resources available, the types of resources provided by the Makerere University Library, the factors affecting resource utilization. The study was ...

  10. Complete mitochondrial genome of the Freshwater Catfish Rita rita (Siluriformes, Bagridae).

    Science.gov (United States)

    Lashari, Punhal; Laghari, Muhammad Younis; Xu, Peng; Zhao, Zixia; Jiang, Li; Narejo, Naeem Tariq; Deng, Yulin; Sun, Xiaowen; Zhang, Yan

    2015-01-01

    The complete mitochondrial genome of Catfish, Rita rita, was isolated by LA PCR (TakaRa LAtaq, Dalian, China); and sequenced by Sanger's method to obtain the complete mitochondrial genome, which is listed Critically Endangered and Red Listed species. The complete mitogenome was 16,449 bp in length and contains 13 typical vertebrate protein-coding genes, 2 rRNA and 22 tRNA genes. The whole genome base composition was estimated to be 33.40% A, 27.43% C, 14.26% G and 24.89% T. The complete mitochondrial genome of catfish, Rita rita provides the basis for genetic breeding and conservation studies.

  11. Users satisfaction with electronic information resources and services ...

    African Journals Online (AJOL)

    This study investigated users satisfaction on the use of electronic information resources and services in MTN Net libraries in ABU & UNIBEN. Two objectives and one null hypotheses were formulated and tested with respect to the users' satisfaction on electronic information resources and services in MTN Net libraries in ...

  12. The Role of the Acquisitions Librarian in Electronic Resources Management

    Science.gov (United States)

    Pomerantz, Sarah B.

    2010-01-01

    With the ongoing shift to electronic formats for library resources, acquisitions librarians, like the rest of the profession, must adapt to the rapidly changing landscape of electronic resources by keeping up with trends and mastering new skills related to digital publishing, technology, and licensing. The author sought to know what roles…

  13. Selection and Evaluation of Electronic Resources

    Directory of Open Access Journals (Sweden)

    Doğan Atılgan

    2013-11-01

    Full Text Available Publication boom and issues related to controlling and accession of printed sources have created some problems after World War II. Consequently, publishing industry has encountered the problem of finding possible solution for emerged situation. Industry of electronic publishing has started to improve with the rapid increase of the price of printed sources as well as the problem of publication boom. The first effects of electronic publishing were appeared on the academic and scholarly publications then electronic publishing became a crucial part of all types of publications. As a result of these developments, collection developments and service policies of information centers were also significantly changed. In this article, after a general introduction about selection and evaluation processes of electronic publications, the subscribed databases by a state and a privately owned university in Turkey and their usage were examined.

  14. Improving Electronic Resources through Holistic Budgeting

    Science.gov (United States)

    Kusik, James P.; Vargas, Mark A.

    2009-01-01

    To establish a more direct link between its collections and the educational goals of Saint Xavier University, the Byrne Memorial Library has adopted a "holistic" approach to collection development. This article examines how traditional budget practices influenced the library's selection of resources and describes how holistic collection…

  15. Page 170 Use of Electronic Resources by Undergraduates in Two ...

    African Journals Online (AJOL)

    undergraduate students use electronic resources such as NUC virtual library, HINARI, ... web pages articles from magazines, encyclopedias, pamphlets and other .... of Nigerian university libraries have Internet connectivity, some of the system.

  16. Utilisation of Electronic Information Resources By Lecturers in ...

    African Journals Online (AJOL)

    This study assesses the use of information resources, specifically, electronic databases by lecturers/teachers in Universities and Colleges of Education in South Western Nigeria. Information resources are central to teachers' education. It provides lecturers/teachers access to information that enhances research and ...

  17. Preservation and conservation of electronic information resources of ...

    African Journals Online (AJOL)

    The major holdings of the broadcast libraries of the Nigerian Television Authority (NTA) are electronic information resources; therefore, providing safe places for general management of these resources have aroused interest in the industry in Nigeria for sometimes. The need to study the preservation and conservation of ...

  18. Using XML Technologies to Organize Electronic Reference Resources

    OpenAIRE

    Huser, Vojtech; Del Fiol, Guilherme; Rocha, Roberto A.

    2005-01-01

    Provision of access to reference electronic resources to clinicians is becoming increasingly important. We have created a framework for librarians to manage access to these resources at an enterprise level, rather than at the individual hospital libraries. We describe initial project requirements, implementation details, and some preliminary results.

  19. Euler European Libraries and Electronic Resources in Mathematical Sciences

    CERN Document Server

    The Euler Project. Karlsruhe

    The European Libraries and Electronic Resources (EULER) Project in Mathematical Sciences provides the EulerService site for searching out "mathematical resources such as books, pre-prints, web-pages, abstracts, proceedings, serials, technical reports preprints) and NetLab (for Internet resources), this outstanding engine is capable of simple, full, and refined searches. It also offers a browse option, which responds to entries in the author, keyword, and title fields. Further information about the Project is provided at the EULER homepage.

  20. Building an electronic resource collection a practical guide

    CERN Document Server

    Lee, Stuart D

    2004-01-01

    This practical book guides information professionals step-by-step through building and managing an electronic resource collection. It outlines the range of electronic products currently available in abstracting and indexing, bibliographic, and other services and then describes how to effectively select, evaluate and purchase them.

  1. Lens proteome map and alpha-crystallin profile of the catfish Rita rita.

    Science.gov (United States)

    Mohanty, Bimal Prasanna; Bhattacharjee, Soma; Das, Manas Kumar

    2011-02-01

    Crystallins are a diverse group of proteins that constitute nearly 90% of the total soluble proteins of the vertebrate eye lens and these tightly packed crystallins are responsible for transparency of the lens. These proteins have been studied in different model and non-model species for understanding the modifications they undergo with ageing that lead to cataract, a disease of protein aggregation. In the present investigation, we studied the lens crystallin profile of the tropical freshwater catfish Rita rita. Profiles of lens crystallins were analyzed and crystallin proteome maps of Rita rita were generated for the first time. alphaA-crystallins, member of the alpha-crystallin family, which are molecular chaperons and play crucial role in maintaining lens transparency were identified by 1- and 2-D immunoblot analysis with anti-alphaA-crystallin antibody. Two protein bands of 19-20 kDa were identified as alphaA-crystallins on 1-D immunoblots and these bands separated into 10 discrete spots on 2-D immunoblot. However, anti-alphaB-crystallin and antiphospho-alphaB-crystallin antibodies were not able to detect any immunoreactive bands on 1- and 2-D immunoblots, indicating alphaB-crystallin was either absent or present in extremely low concentration in Rita rita lens. Thus, Rita rita alpha-crystallins are more like that of the catfish Clarias batrachus and the mammal kangaroo in its alphaA- and alphaB-crystallin content (contain low amount from 5-9% of alphaB-crystallin) and unlike the dogfish, zebrafish, human, bovine and mouse alpha-crystallins (contain higher amount of alphaB-crystallin from 25% in mouse and bovine to 85% in dogfish). Results of the present study can be the baseline information for stimulating further investigation on Rita rita lens crystallins for comparative lens proteomics. Comparing and contrasting the alpha-crystallins of the dogfish and Rita rita may provide valuable information on the functional attributes of alphaA- and alphaB-isoforms, as

  2. Organizational matters of competition in electronic educational resources

    Directory of Open Access Journals (Sweden)

    Ирина Карловна Войтович

    2015-12-01

    Full Text Available The article examines the experience of the Udmurt State University in conducting competitions of educational publications and electronic resources. The purpose of such competitions is to provide methodological support to educational process. The main focus is on competition of electronic educational resources. The technology of such contests is discussed through detailed analysis of the main stages of the contest. It is noted that the main task of the preparatory stage of the competition is related to the development of regulations on competition and the definition of criteria for selection of the submitted works. The paper also proposes a system of evaluation criteria of electronic educational resources developed by members of the contest organizing committee and jury members. The article emphasizes the importance of not only the preparatory stages of the competition, but also measures for its completion, aimed at training teachers create quality e-learning resources.

  3. Looking at the future with Rita.

    Science.gov (United States)

    Bentivoglio, M

    2013-11-12

    This paper on Rita Levi-Montalcini (1909-2012), who received in 1986 the Nobel Prize in Physiology or Medicine for the discovery of nerve growth factor, focuses on aspects of her advocacy and her commitment to education in which she has been especially active in the last part of her long life. With passionate confidence on the capabilities of the aging brain (together with severe admonition against the pursuit of immortality), she encouraged contributions of senior citizens to the society. Always projected into the future, with enduring faith in the potential of young individuals, in education as a key to development, in the capabilities of women, in the importance of gender equality, Rita established in 2001 the Rita Levi-Montalcini Foundation for the education of African women. Her legacy on engagement for a better 'global village' should not be forgotten by the neuroscience community.

  4. Realizing the full potential of a RITA spectrometer

    DEFF Research Database (Denmark)

    Lefmann, K.; Niedermayer, C.; Abrahamsen, A.B.

    2006-01-01

    The “re-invented triple-axis spectrometer (RITA) concept has existed for a decade. Recent developments at RITA-2 at PSI, have revealed more of the potential of this instrument class. We demonstrate the performance of the multi-blade imaging mode, which has been applied e.g. to studies of dispersion...... relations and emphasize the power of this mode in combination with the low background of RITA-2. In addition, we present other ways of utilizing the position sensitive detector in a RITA instrument. Simulations of a planned upgrade of the guide-monochromator system at RITA-2 have shown a potential...

  5. Why and How to Measure the Use of Electronic Resources

    Directory of Open Access Journals (Sweden)

    Jean Bernon

    2008-11-01

    Full Text Available A complete overview of library activity implies a complete and reliable measurement of the use of both electronic resources and printed materials. This measurement is based on three sets of definitions: document types, use types and user types. There is a common model of definitions for printed materials, but a lot of questions and technical issues remain for electronic resources. In 2006 a French national working group studied these questions. It relied on the COUNTER standard, but found it insufficient and pointed out the need for local tools such as web markers and deep analysis of proxy logs. Within the French national consortium COUPERIN, a new working group is testing ERMS, SUSHI standards, Shibboleth authentication, along with COUNTER standards, to improve the counting of the electronic resources use. At this stage this counting is insufficient and its improvement will be a European challenge for the future.

  6. Antibacterial properties of the skin mucus of the freshwater fishes, Rita rita and Channa punctatus.

    Science.gov (United States)

    Kumari, U; Nigam, A K; Mitial, S; Mitial, A K

    2011-07-01

    The skin mucus of Rita rita and Channa punctatus was investigated to explore the possibilities of its antibacterial properties. Skin mucus was extracted in acidic solvents (0.1% trifluoroacetic acid and 3% acetic acid) and in triple distilled water (aqueous medium). The antibacterial activity of the mucus extracts was analyzed, using disc diffusion method, against five strains of bacteria--the Gram-positive Staphylococcus aureus and Micrococcus luteus; and the Gram negative Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi. In both Rita rita and Channa punctatus, the skin mucus extracted in acidic solvents as well as in aqueous medium show antibacterial activity against Staphylococcus aureus and Micrococcus luteus. Nevertheless, the activity is higher in acidic solvents than that in aqueous medium. The acidic mucus extracts of Rita rita, show antibacterial activity against Salmonella typhi as well. The results suggest that fish skin mucus have bactericidal properties and thus play important role in the protection of fish against the invasion of pathogens. Fish skin mucus could thus be regarded as a potential source of novel antibacterial components.

  7. Access to electronic resources by visually impaired people

    Directory of Open Access Journals (Sweden)

    Jenny Craven

    2003-01-01

    Full Text Available Research into access to electronic resources by visually impaired people undertaken by the Centre for Research in Library and Information Management has not only explored the accessibility of websites and levels of awareness in providing websites that adhere to design for all principles, but has sought to enhance understanding of information seeking behaviour of blind and visually impaired people when using digital resources.

  8. Integration& Operation of a Microgrid at Santa Rita Jail

    Energy Technology Data Exchange (ETDEWEB)

    Chevron Energy Solutions; Alameda County; DeForest, Nicholas; Lai, Judy; Stadler, Michael; Mendes, Goncalo; Marnay, Chris; Donadee, Jon

    2011-05-01

    Santa Rita Jail is a 4,500 inmate facility located in Dublin CA, approximately 40 miles (65 km) east of San Francisco. Over the past decade, a series of Distributed Energy Resources (DER) installations and efficiency measures have been undertaken to transform the 3MW facility into a"Green Jail". These include a 1.2MW rated rooftop PV system installed in 2002, a 1MW molten carbonate fuel cell with CHP, and retrofits to lighting and HVAC systems to reduce peak loads. With the upcoming installation of a large-scale battery and fast static disconnect switch, Santa Rita Jail will become a true microgrid, with full CERTS Microgrid functionality. Consequently, the jail will be able to seamlessly disconnect from the grid and operate as an island in the event of a disturbance, reconnecting again once the disturbance has dissipated. The extent to which that jail is capable of islanding is principally dependant on the energy capacity of the battery-one focus of this investigation. Also presented here are overviews of the DER currently installed at the jail, as well as the value it provides by offsetting the purchase of electricity under the current Pacific Gas& Electric (PG&E) tariff.

  9. Practical guide to electronic resources in the humanities

    CERN Document Server

    Dubnjakovic, Ana

    2010-01-01

    From full-text article databases to digitized collections of primary source materials, newly emerging electronic resources have radically impacted how research in the humanities is conducted and discovered. This book, covering high-quality, up-to-date electronic resources for the humanities, is an easy-to-use annotated guide for the librarian, student, and scholar alike. It covers online databases, indexes, archives, and many other critical tools in key humanities disciplines including philosophy, religion, languages and literature, and performing and visual arts. Succinct overviews of key eme

  10. Krimmi-Rita juubelituur Eestimaal / Enda Trubok

    Index Scriptorium Estoniae

    Trubok, Enda

    2010-01-01

    Kontši-Savva ehk Krasnodarka küla eesti seltsi esinaisel Rita Kadilkinal (neiupõlvenimi Kuusk), kelle esivanemad 1862. aastal Järvamaalt – Albu vallast – Krimmi paremaid maid otsima läksid, täitus septembris 70 eluaastat, mille puhul otsustaski ta Eestisse tulla

  11. Discipline, availability of electronic resources and the use of Finnish National Electronic Library - FinELib

    Directory of Open Access Journals (Sweden)

    Sanna Torma

    2004-01-01

    Full Text Available This study elaborated relations between digital library use by university faculty, users' discipline and the availability of key resources in the Finnish National Electronic Library (FinELib, Finnish national digital library, by using nationwide representative survey data. The results show that the perceived availability of key electronic resources by researchers in FinELib was a stronger predictor of the frequency and purpose of use of its services than users' discipline. Regardless of discipline a good perceived provision of central resources led to a more frequent use of FinELib. The satisfaction with the services did not vary with the discipline, but with the perceived availability of resources.

  12. Access to electronic information resources by students of federal ...

    African Journals Online (AJOL)

    The paper discusses access to electronic information resources by students of Federal Colleges of Education in Eha-Amufu and Umunze. Descriptive survey design was used to investigate sample of 526 students. Sampling technique used was a Multi sampling technique. Data for the study were generated using ...

  13. Electronic Commerce Resource Centers. An Industry--University Partnership.

    Science.gov (United States)

    Gulledge, Thomas R.; Sommer, Rainer; Tarimcilar, M. Murat

    1999-01-01

    Electronic Commerce Resource Centers focus on transferring emerging technologies to small businesses through university/industry partnerships. Successful implementation hinges on a strategic operating plan, creation of measurable value for customers, investment in customer-targeted training, and measurement of performance outputs. (SK)

  14. ANALYTICAL REVIEW OF ELECTRONIC RESOURCES FOR THE STUDY OF LATIN

    Directory of Open Access Journals (Sweden)

    Olena Yu. Balalaieva

    2014-04-01

    Full Text Available The article investigates the current state of development of e-learning content in the Latin language. It is noted that the introduction of ICT in the educational space has expanded the possibility of studying Latin, opened access to digital libraries resources, made it possible to use scientific and educational potential and teaching Latin best practices of world's leading universities. A review of foreign and Ukrainian information resources and electronic editions for the study of Latin is given. Much attention was paid to the didactic potential of local and online multimedia courses of Latin, electronic textbooks, workbooks of interactive tests and exercises, various dictionaries and software translators, databases and digital libraries. Based on analysis of the world market of educational services and products the main trends in the development of information resources and electronic books are examined. It was found that multimedia courses with interactive exercises or workbooks with interactive tests, online dictionaries and translators are the most widely represented and demanded. The noticeable lagging of Ukrainian education and computer linguistics in quantitative and qualitative measures in this industry is established. The obvious drawback of existing Ukrainian resources and electronic editions for the study of Latin is their noninteractive nature. The prospects of e-learning content in Latin in Ukraine are outlined.

  15. Adoption and use of electronic information resources by medical ...

    African Journals Online (AJOL)

    This study investigated the adoption and use of electronic information resources by medical science students of the University of Benin. The descriptive survey research design was adopted for the study and 390 students provided the data. Data collected were analysed with descriptive Statistics(Simple percentage and ...

  16. Modern ICT Tools: Online Electronic Resources Sharing Using Web ...

    African Journals Online (AJOL)

    Modern ICT Tools: Online Electronic Resources Sharing Using Web 2.0 and Its Implications For Library And Information Practice In Nigeria. ... The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader). If you would like more ...

  17. Technical Communicator: A New Model for the Electronic Resources Librarian?

    Science.gov (United States)

    Hulseberg, Anna

    2016-01-01

    This article explores whether technical communicator is a useful model for electronic resources (ER) librarians. The fields of ER librarianship and technical communication (TC) originated and continue to develop in relation to evolving technologies. A review of the literature reveals four common themes for ER librarianship and TC. While the…

  18. MODEL OF AN ELECTRONIC EDUCATIONAL RESOURCE OF NEW GENERATION

    Directory of Open Access Journals (Sweden)

    Anatoliy V. Loban

    2016-01-01

    Full Text Available The mathematical structure of the modular architecture of an electronic educational resource (EER of new generation, which allows to decompose the process of studying the subjects of the course at a hierarchically ordered set of data (knowledge and procedures for manipulating them, to determine the roles of participants of process of training of and technology the development and use of EOR in the study procrate.

  19. Retention of Displaced Students after Hurricanes Katrina and Rita

    Science.gov (United States)

    Coco, Joshua Christian

    2017-01-01

    The purpose of the study was to investigate the strategies that university leaders implemented to improve retention of displaced students in the aftermaths of Hurricanes Katrina and Rita. The universities that participated in this study admitted displaced students after Hurricanes Katrina and Rita. This study utilized a qualitative…

  20. Simulations and experiments on RITA-2 at PSI

    DEFF Research Database (Denmark)

    Klausen, S.N.; Lefmann, K.; McMorrow, D.F.

    2002-01-01

    The cold-neutron triple-axis spectrometer RITA-2 designed and built at Riso National Laboratory was installed at the neutron source SINQ at Paul Scherrer Institute in April/May 2001. In connection with the installation of RITA-2, computer simulations were performed using the neutron ray...

  1. Realizing the full potential of a RITA spectrometer

    International Nuclear Information System (INIS)

    Lefmann, K.; Niedermayer, Ch.; Abrahamsen, A.B.; Bahl, C.R.H.; Christensen, N.B.; Jacobsen, H.S.; Larsen, T.L.; Haefliger, P.; Filges, U.; Ronnow, H.M.

    2006-01-01

    The 're-invented triple-axis spectrometer (RITA) concept has existed for a decade. Recent developments at RITA-2 at PSI, have revealed more of the potential of this instrument class. We demonstrate the performance of the multi-blade imaging mode, which has been applied e.g. to studies of dispersion relations and emphasize the power of this mode in combination with the low background of RITA-2. In addition, we present other ways of utilizing the position sensitive detector in a RITA instrument. Simulations of a planned upgrade of the guide-monochromator system at RITA-2 have shown a potential to increase the flux at the sample position by a factor 5

  2. Realizing the full potential of a RITA spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Lefmann, K. [Riso National Laboratory, Frederiksborgvej 399, DK-4000 Roskilde (Denmark)]. E-mail: kim.lefmann@risoe.dk; Niedermayer, Ch. [Laboratory for Neutron Scattering, ETH-Zuerich and Paul Scherrer Institut, CH-5232 Villilgen (Switzerland); Abrahamsen, A.B. [Riso National Laboratory, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Bahl, C.R.H. [Riso National Laboratory, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Christensen, N.B. [Riso National Laboratory, Frederiksborgvej 399, DK-4000 Roskilde (Denmark): Laboratory for Neutron Scattering, ETH-Zuerich and Paul Scherrer Institut, CH-5232 Villilgen (Switzerland); Jacobsen, H.S. [Niels Bohr Institute, University of Copenhagen, DK-2100 Copenhagen O (Denmark); Larsen, T.L. [Niels Bohr Institute, University of Copenhagen, DK-2100 Copenhagen O (Denmark); Haefliger, P. [Laboratory for Neutron Scattering, ETH-Zuerich and Paul Scherrer Institut, CH-5232 Villilgen (Switzerland); Filges, U. [Laboratory for Neutron Scattering, ETH-Zuerich and Paul Scherrer Institut, CH-5232 Villilgen (Switzerland); Ronnow, H.M. [Laboratory for Neutron Scattering, ETH-Zuerich and Paul Scherrer Institut, CH-5232 Villilgen (Switzerland)

    2006-11-15

    The 're-invented triple-axis spectrometer (RITA) concept has existed for a decade. Recent developments at RITA-2 at PSI, have revealed more of the potential of this instrument class. We demonstrate the performance of the multi-blade imaging mode, which has been applied e.g. to studies of dispersion relations and emphasize the power of this mode in combination with the low background of RITA-2. In addition, we present other ways of utilizing the position sensitive detector in a RITA instrument. Simulations of a planned upgrade of the guide-monochromator system at RITA-2 have shown a potential to increase the flux at the sample position by a factor 5.

  3. Morphological observation and length-weight relationship of critically endangered riverine catfish Rita rita (Hamilton).

    Science.gov (United States)

    Amin, M R; Mollah, M F A; Taslima, K; Muhammadullah

    2014-01-15

    The experiment was conducted to investigate the morphological status of the critically endangered riverine catfish Rita rita using morphometric and meristic traits. About 158 species of Rita were collected from the old Brahmaputra river in Mymensingh district and were studied in the laboratory of the Fisheries Biology and Genetics Department, Bangladesh Agricultural University. Measurement of length and weight of Rita were recorded by using measuring scale and electric balance respectively. Significant curvilinear relationship existed between total length and other morphometric characters and between head length and other characters of the head. Relationships between total length and various body measurements of the fish were highly significant (p < 0.01) except the relationship between total length and pelvic fin length of male fish (p < 0.05). In case of meristic characters-dorsal fin rays, pelvic fin rays, pectoral fin rays, anal fin rays, caudal fin rays, number of vertebrae and branchiostegal rays were found to be more or less similar except slight differences. The values of condition factors (k) in the total length body-weight relationships for female and male were found to be 0.41 and 0.38, respectively. The mean values of relative condition factors (kn) were 1.0 and 1.005 for female and male, respectively.

  4. End-of-life resource recovery from emerging electronic products

    DEFF Research Database (Denmark)

    Parajuly, Keshav; Habib, Komal; Cimpan, Ciprian

    2016-01-01

    Integrating product design with appropriate end-of-life (EoL) processing is widely recognized to have huge potentials in improving resource recovery from electronic products. In this study, we investigate both the product characteristics and EoL processing of robotic vacuum cleaner (RVC), as a case...... of emerging electronic product, in order to understand the recovery fate of different materials and its linkage to product design. Ten different brands of RVC were dismantled and their material composition and design profiles were studied. Another 125 RVCs (349 kg) were used for an experimental trial...... at a conventional ‘shred-and-separate’ type preprocessing plant in Denmark. A detailed material flow analysis was performed throughout the recycling chain. The results show a mismatch between product design and EoL processing, and the lack of practical implementation of ‘Design for EoL’ thinking. In the best...

  5. Analysis of Human Resources Management Strategy in China Electronic Commerce Enterprises

    Science.gov (United States)

    Shao, Fang

    The paper discussed electronic-commerce's influence on enterprise human resources management, proposed and proved the human resources management strategy which electronic commerce enterprise should adopt from recruitment strategy to training strategy, keeping talent strategy and other ways.

  6. RITA: The reinvented triple axis spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Mason, T.E. [Toronto Univ., ON (Canada). Dept. of Physics; Clausen, K.N.; Aeppli, G.; McMorrow, D.R.; Kjems, J.K. [Risoe National Lab., Roskilde (Denmark)

    1995-11-01

    Risoe National Laboratory was reported to be in the process of developing a new spectrometer design, RITA, based on the triple axis design. The spectrometer will attempt to incorporate more recent innovations such as multilayer supermirrors and microstrip proportional counters into a rethinking of the triple-axis spectrometer. By optimizing the beam optics, using supermirrors and extending the analyser to map regions of (Q, {omega}) space using an array of independently controllable pyrolytic graphite crystals focussed on an area detector, it was hoped that the efficiency of single-crystal inelastic experiments could be increased by as much as a factor of 20. 7 figs., 20 refs.

  7. Effects of Electronic Information Resources Skills Training for Lecturers on Pedagogical Practices and Research Productivity

    Science.gov (United States)

    Bhukuvhani, Crispen; Chiparausha, Blessing; Zuvalinyenga, Dorcas

    2012-01-01

    Lecturers use various electronic resources at different frequencies. The university library's information literacy skills workshops and seminars are the main sources of knowledge of accessing electronic resources. The use of electronic resources can be said to have positively affected lecturers' pedagogical practices and their work in general. The…

  8. Electronic Resources and Mission Creep: Reorganizing the Library for the Twenty-First Century

    Science.gov (United States)

    Stachokas, George

    2009-01-01

    The position of electronic resources librarian was created to serve as a specialist in the negotiation of license agreements for electronic resources, but mission creep has added more functions to the routine work of electronic resources such as cataloging, gathering information for collection development, and technical support. As electronic…

  9. RITA Mimics: Synthesis and Mechanistic Evaluation of Asymmetric Linked Trithiazoles.

    Science.gov (United States)

    Pietkiewicz, Adrian L; Zhang, Yuqi; Rahimi, Marwa N; Stramandinoli, Michael; Teusner, Matthew; McAlpine, Shelli R

    2017-04-13

    The established cytotoxic agent RITA contains a thiophene-furan-thiophene backbone and two terminal alcohol groups. Herein we investigate the effect of using thiazoles as the backbone in RITA-like molecules and modifying the terminal groups of these trithiazoles, thereby generating 41 unique structures. Incorporating side chains with varied steric bulk allowed us to investigate how size and a stereocenter impacted biological activity. Subjecting compounds to growth inhibition assays on HCT-116 cells showed that the most potent compounds 7d , 7e , and 7h had GI 50 values of 4.4, 4.4, and 3.4 μM, respectively, versus RITA (GI 50 of 800 nM). Analysis of these compounds in apoptosis assays proved that 7d , 7e , and 7h were as effective as RITA at inducing apoptosis. Evaluating the impact of 7h on proteins targeted by RITA (p53, c-Myc, and Mcl-1) indicated that it acts via a different mechanism of action to that of RITA. RITA suppressed Mcl-1 protein via p53, whereas compound 7h suppressed Mcl-1 expression via an alternative mechanism independent of p53.

  10. Electronic Document Management: A Human Resource Management Case Study

    Directory of Open Access Journals (Sweden)

    Thomas Groenewald

    2004-11-01

    Full Text Available This case study serve as exemplar regarding what can go wrong with the implementation of an electronic document management system. Knowledge agility and knowledge as capital, is outlined against the backdrop of the information society and knowledge economy. The importance of electronic document management and control is sketched thereafter. The literature review is concluded with the impact of human resource management on knowledge agility, which includes references to the learning organisation and complexity theory. The intervention methodology, comprising three phases, follows next. The results of the three phases are presented thereafter. Partial success has been achieved with improving the human efficacy of electronic document management, however the client opted to discontinue the system in use. Opsomming Die gevalle studie dien as voorbeeld van wat kan verkeerd loop met die implementering van ’n elektroniese dokumentbestuur sisteem. Teen die agtergrond van die inligtingsgemeenskap en kennishuishouding word kennissoepelheid en kennis as kapitaal bespreek. Die literatuurstudie word afgesluit met die inpak van menslikehulpbronbestuur op kennissoepelheid, wat ook die verwysings na die leerorganisasie en kompleksietydsteorie insluit. Die metodologie van die intervensie, wat uit drie fases bestaan, volg daarna. Die resultate van die drie fases word vervolgens aangebied. Slegs gedeelte welslae is behaal met die verbetering van die menslike doeltreffendheid ten opsigte van elektroniese dokumentbestuur. Die klient besluit egter om nie voort te gaan om die huidige sisteem te gebruik nie.

  11. Children and Trauma: A Post-Katrina and Rita Response

    Science.gov (United States)

    Hebert, Barbara B.; Ballard, Mary B.

    2007-01-01

    Many children have struggled to cope with the traumatic experiences brought about by hurricanes Katrina and Rita. This article recounts how the authors intervened in the lives of children and families after the storms. (Contains 3 figures.)

  12. Rita Felski, The Limits of Critique

    Directory of Open Access Journals (Sweden)

    Corrado Confalonieri

    2017-05-01

    Full Text Available Professore di Letteratura inglese presso la University of Virginia – e dal 2016 Niels Bohr Professor alla University of Southern Denmark per un progetto quinquennale dedicato agli usi sociali della letteratura –, Rita Felski non è, all’interno del gruppo di studiosi che lavorano negli Stati Uniti, tra quelli più noti al pubblico italiano, e ciò non soltanto perché mancano traduzioni dei suoi libri, ma per il fatto che diversi tra questi sono rivolti a un contesto piuttosto specificamente americano. Non fa eccezione The Limits of Critique, il libro che qui si presenta e che dovrebbe costituire la seconda uscita di una trilogia avviata nel 2008 con Uses of Literature (Wiley-Blackwell e destinata a concludersi con un volume ora in fase di elaborazione dedicato al coinvolgimento estetico e alle ragioni per cui, come lettori o spettatori, siamo affascinati da un’opera d’arte.

  13. External factors impacting hospital evacuations caused by Hurricane Rita: the role of situational awareness.

    Science.gov (United States)

    Downey, Erin L; Andress, Knox; Schultz, Carl H

    2013-06-01

    The 2005 Gulf Coast hurricane season was one of the most costly and deadly in US history. Hurricane Rita stressed hospitals and led to multiple, simultaneous evacuations. This study systematically identified community factors associated with patient movement out of seven hospitals evacuated during Hurricane Rita. This study represents the second of two systematic, observational, and retrospective investigations of seven acute care hospitals that reported off-site evacuations due to Hurricane Rita. Participants from each hospital included decision makers that comprised the Incident Management Team (IMT). Investigators applied a standardized interview process designed to assess evacuation factors related to external situational awareness of community activities during facility evacuation due to hurricanes. The measured outcomes were responses to 95 questions within six sections of the survey instrument. Investigators identified two factors that significantly impacted hospital IMT decision making: (1) incident characteristics affecting a facility's internal resources and challenges; and (2) incident characteristics affecting a facility's external evacuation activities. This article summarizes the latter and reports the following critical decision making points: (1) Emergency Operations Plans (EOP) were activated an average of 85 hours (3 days, 13 hours) prior to Hurricane Rita's landfall; (2) the decision to evacuate the hospital was made an average of 30 hours (1 day, 6 hours) from activation of the EOP; and (3) the implementation of the evacuation process took an average of 22 hours. Coordination of patient evacuations was most complicated by transportation deficits (the most significant of the 11 identified problem areas) and a lack of situational awareness of community response activities. All evacuation activities and subsequent evacuation times were negatively impacted by an overall lack of understanding on the part of hospital staff and the IMT regarding how to

  14. Electronic Safety Resource Tools -- Supporting Hydrogen and Fuel Cell Commercialization

    Energy Technology Data Exchange (ETDEWEB)

    Barilo, Nick F.

    2014-09-29

    The Pacific Northwest National Laboratory (PNNL) Hydrogen Safety Program conducted a planning session in Los Angeles, CA on April 1, 2014 to consider what electronic safety tools would benefit the next phase of hydrogen and fuel cell commercialization. A diverse, 20-person team led by an experienced facilitator considered the question as it applied to the eight most relevant user groups. The results and subsequent evaluation activities revealed several possible resource tools that could greatly benefit users. The tool identified as having the greatest potential for impact is a hydrogen safety portal, which can be the central location for integrating and disseminating safety information (including most of the tools identified in this report). Such a tool can provide credible and reliable information from a trustworthy source. Other impactful tools identified include a codes and standards wizard to guide users through a series of questions relating to application and specific features of the requirements; a scenario-based virtual reality training for first responders; peer networking tools to bring users from focused groups together to discuss and collaborate on hydrogen safety issues; and a focused tool for training inspectors. Table ES.1 provides results of the planning session, including proposed new tools and changes to existing tools.

  15. Controlling user access to electronic resources without password

    Science.gov (United States)

    Smith, Fred Hewitt

    2015-06-16

    Described herein are devices and techniques for remotely controlling user access to a restricted computer resource. The process includes pre-determining an association of the restricted computer resource and computer-resource-proximal environmental information. Indicia of user-proximal environmental information are received from a user requesting access to the restricted computer resource. Received indicia of user-proximal environmental information are compared to associated computer-resource-proximal environmental information. User access to the restricted computer resource is selectively granted responsive to a favorable comparison in which the user-proximal environmental information is sufficiently similar to the computer-resource proximal environmental information. In at least some embodiments, the process further includes comparing user-supplied biometric measure and comparing it with a predetermined association of at least one biometric measure of an authorized user. Access to the restricted computer resource is granted in response to a favorable comparison.

  16. Rita Kirke: "Taimed on minu head õpetajad ja toetajad" / Rita Kirke

    Index Scriptorium Estoniae

    Kirke, Rita

    2006-01-01

    Elukutselisi aiakujundajaid tutvustavas sarjas vastab küsimustele läti aiakujundaja Rita Kirke. R. Kirkest, tema tähtsamad tööd. R. Kirke endast, oma õpetajatest, oma aiast ja töödest, Läti oludesse sobivast ja tüüpilisest Läti aiast, koostööst klientidega, lemmiktaimedest, taimede kättesaadavusest Lätis jpm. Ill.: R. Kirke portreefoto, 6 ill. tema töödest

  17. The Internet School of Medicine: use of electronic resources by medical trainees and the reliability of those resources.

    Science.gov (United States)

    Egle, Jonathan P; Smeenge, David M; Kassem, Kamal M; Mittal, Vijay K

    2015-01-01

    Electronic sources of medical information are plentiful, and numerous studies have demonstrated the use of the Internet by patients and the variable reliability of these sources. Studies have investigated neither the use of web-based resources by residents, nor the reliability of the information available on these websites. A web-based survey was distributed to surgical residents in Michigan and third- and fourth-year medical students at an American allopathic and osteopathic medical school and a Caribbean allopathic school regarding their preferred sources of medical information in various situations. A set of 254 queries simulating those faced by medical trainees on rounds, on a written examination, or during patient care was developed. The top 5 electronic resources cited by the trainees were evaluated for their ability to answer these questions accurately, using standard textbooks as the point of reference. The respondents reported a wide variety of overall preferred resources. Most of the 73 responding medical trainees favored textbooks or board review books for prolonged studying, but electronic resources are frequently used for quick studying, clinical decision-making questions, and medication queries. The most commonly used electronic resources were UpToDate, Google, Medscape, Wikipedia, and Epocrates. UpToDate and Epocrates had the highest percentage of correct answers (47%) and Wikipedia had the lowest (26%). Epocrates also had the highest percentage of wrong answers (30%), whereas Google had the lowest percentage (18%). All resources had a significant number of questions that they were unable to answer. Though hardcopy books have not been completely replaced by electronic resources, more than half of medical students and nearly half of residents prefer web-based sources of information. For quick questions and studying, both groups prefer Internet sources. However, the most commonly used electronic resources fail to answer clinical queries more than half

  18. Developing Humanities Collections in the Digital Age: Exploring Humanities Faculty Engagement with Electronic and Print Resources

    Science.gov (United States)

    Kachaluba, Sarah Buck; Brady, Jessica Evans; Critten, Jessica

    2014-01-01

    This article is based on quantitative and qualitative research examining humanities scholars' understandings of the advantages and disadvantages of print versus electronic information resources. It explores how humanities' faculty members at Florida State University (FSU) use print and electronic resources, as well as how they perceive these…

  19. Electronic resource management practical perspectives in a new technical services model

    CERN Document Server

    Elguindi, Anne

    2012-01-01

    A significant shift is taking place in libraries, with the purchase of e-resources accounting for the bulk of materials spending. Electronic Resource Management makes the case that technical services workflows need to make a corresponding shift toward e-centric models and highlights the increasing variety of e-formats that are forcing new developments in the field.Six chapters cover key topics, including: technical services models, both past and emerging; staffing and workflow in electronic resource management; implementation and transformation of electronic resource management systems; the ro

  20. Mapping Hurricane Rita inland storm tide

    Science.gov (United States)

    Berenbrock, Charles; Mason, Jr., Robert R.; Blanchard, Stephen F.; Simonovic, Slobodan P.

    2009-01-01

    Flood-inundation data are most useful for decision makers when presented in the context of maps of effected communities and (or) areas. But because the data are scarce and rarely cover the full extent of the flooding, interpolation and extrapolation of the information are needed. Many geographic information systems (GIS) provide various interpolation tools, but these tools often ignore the effects of the topographic and hydraulic features that influence flooding. A barrier mapping method was developed to improve maps of storm tide produced by Hurricane Rita. Maps were developed for the maximum storm tide and at 3-hour intervals from midnight (0000 hour) through noon (1200 hour) on September 24, 2005. The improved maps depict storm-tide elevations and the extent of flooding. The extent of storm-tide inundation from the improved maximum storm-tide map was compared to the extent of flood-inundation from a map prepared by the Federal Emergency Management Agency (FEMA). The boundaries from these two maps generally compared quite well especially along the Calcasieu River. Also a cross-section profile that parallels the Louisiana coast was developed from the maximum storm-tide map and included FEMA high-water marks.

  1. Electronic resources access and usage among the postgraduates of ...

    African Journals Online (AJOL)

    ... and usage among the postgraduates of a Nigerian University of Technology. ... faced by postgraduates in using e-resources include takes too much time to find, ... Resources, Access, Use, Postgraduat, Students, University, Technology, Nigeria ... By Country · List All Titles · Free To Read Titles This Journal is Open Access.

  2. Targeting NF-κB RelA/p65 phosphorylation overcomes RITA resistance.

    Science.gov (United States)

    Bu, Yiwen; Cai, Guoshuai; Shen, Yi; Huang, Chenfei; Zeng, Xi; Cao, Yu; Cai, Chuan; Wang, Yuhong; Huang, Dan; Liao, Duan-Fang; Cao, Deliang

    2016-12-28

    Inactivation of p53 occurs frequently in various cancers. RITA is a promising anticancer small molecule that dissociates p53-MDM2 interaction, reactivates p53 and induces exclusive apoptosis in cancer cells, but acquired RITA resistance remains a major drawback. This study found that the site-differential phosphorylation of nuclear factor-κB (NF-κB) RelA/p65 creates a barcode for RITA chemosensitivity in cancer cells. In naïve MCF7 and HCT116 cells where RITA triggered vast apoptosis, phosphorylation of RelA/p65 increased at Ser536, but decreased at Ser276 and Ser468; oppositely, in RITA-resistant cells, RelA/p65 phosphorylation decreased at Ser536, but increased at Ser276 and Ser468. A phosphomimetic mutation at Ser536 (p65/S536D) or silencing of endogenous RelA/p65 resensitized the RITA-resistant cells to RITA while the phosphomimetic mutant at Ser276 (p65/S276D) led to RITA resistance of naïve cells. In mouse xenografts, intratumoral delivery of the phosphomimetic p65/S536D mutant increased the antitumor activity of RITA. Furthermore, in the RITA-resistant cells ATP-binding cassette transporter ABCC6 was upregulated, and silencing of ABCC6 expression in these cells restored RITA sensitivity. In the naïve cells, ABCC6 delivery led to RITA resistance and blockage of p65/S536D mutant-induced RITA sensitivity. Taken together, these data suggest that the site-differential phosphorylation of RelA/p65 modulates RITA sensitivity in cancer cells, which may provide an avenue to manipulate RITA resistance. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  3. Strategic Planning for Electronic Resources Management: A Case Study at Gustavus Adolphus College

    Science.gov (United States)

    Hulseberg, Anna; Monson, Sarah

    2009-01-01

    Electronic resources, the tools we use to manage them, and the needs and expectations of our users are constantly evolving; at the same time, the roles, responsibilities, and workflow of the library staff who manage e-resources are also in flux. Recognizing a need to be more intentional and proactive about how we manage e-resources, the…

  4. Added flexibility in triple axis spectrometers: The two RITAs at Risø

    DEFF Research Database (Denmark)

    Lefmann, K.; McMorrow, D.F.; Rønnow, H.M.

    2000-01-01

    The cold-neutron triple-axis spectrometer RITA-I at Rise has been operational for about three years, and in the near future an improved version, RITA-2 will replace the existing triple-axis instrument TAS7. We review the performance of RITA-1 and the operation modes of its flexible secondary...... spectrometer, giving examples of a few key experiments, and describe the software developed for running it. Further, the design of the new RITA-2 instrument is presented. The two RITA spectrometers are compared with their sister instrument SPINS at NIST and with similar instruments planned elsewhere. (C) 2000...

  5. impact of the use of electronic resources on research output

    African Journals Online (AJOL)

    manda

    ... Julita Nawe. University of Dar Es Salaam Library, P.O. Box 35092, Dar Es Salaam, Tanzania .... significantly, while 28.3% observed that quality of service to the community had improved .... resources and evaluate them is an important area.

  6. Simulations and experiments on RITA-2 at PSI

    International Nuclear Information System (INIS)

    Klausen, S.N.; Lefmann, K.; McMorrow, D.F.; Altorfer, F.; Janssen, S.; Luethy, M.

    2002-01-01

    The cold-neutron triple-axis spectrometer RITA-2 designed and built at Riso National Laboratory was installed at the neutron source SINQ at Paul Scherrer Institute in April/May 2001. In connection with the installation of RITA-2, computer simulations were performed using the neutron ray-tracing package McStas. The simulation results are compared to real experimental results obtained with a powder sample. Especially, the flux at the sample position and the resolution function of the spectrometer are investigated. (orig.)

  7. Ambient Assisted Living and ageing: preliminary results of RITA project.

    Science.gov (United States)

    Aquilano, Michela; Cavallo, Filippo; Bonaccorsi, Manuele; Esposito, Raffaele; Rovini, Erika; Filippi, Massimo; Esposito, Dario; Dario, Paolo; Carrozza, Maria Chiara

    2012-01-01

    The ageing of population is a social phenomenon that most of worldwide countries are facing. They are, and will be even more in the future, indeed trying to find solutions for improving quality of life of their elderly citizens. The project RITA wants to demonstrate that an update of the current socio-medical services with an Ambient Assisted Living (AAL) approach could improve the service efficiency and the quality of life of both elderly and caregiver. This paper presents the preliminary results obtained in RITA.

  8. Simulations and experiments on RITA-2 at PSI

    Science.gov (United States)

    Klausen, S. N.; Lefmann, K.; McMorrow, D. F.; Altorfer, F.; Janssen, S.; Lüthy, M.

    The cold-neutron triple-axis spectrometer RITA-2 designed and built at Riso National Laboratory was installed at the neutron source SINQ at Paul Scherrer Institute in April/May 2001. In connection with the installation of RITA-2, computer simulations were performed using the neutron ray-tracing package McStas. The simulation results are compared to real experimental results obtained with a powder sample. Especially, the flux at the sample position and the resolution function of the spectrometer are investigated.

  9. RITA inhibits growth of human hepatocellular carcinoma through induction of apoptosis.

    Science.gov (United States)

    Wang, Haihe; Chen, Guofu; Wang, Hongzhi; Liu, Chunbo

    2013-01-01

    RBP-J-interacting and tubulin-associated (RITA) is a novel RBP-J-interacting protein that downregulates Notch-mediated transcription. The current study focuses on the antitumor effect of RITA in human hepatocellular carcinoma (HCC) and aims to explore its molecular mechanism. Thirty paired HCC and adjacent non-tumoral liver samples were analyzed by real-time quantitative reverse transcriptase polymerase chain reaction (qRT-PCR). RITA overexpression was induced by transfection of a pcDNA3.1-Flag-RITA plasmid into HepG2 cells. RITA knockdown was achieved by siRNA transfection. mRNA and protein expression of target genes were quantified by qRT-PCR and Western blotting, respectively. Cell proliferation and apoptosis were measured using MTT assay and flow cytometry. Our results demonstrate that adjacent nontumoral liver samples exhibited increased RITA expression compared to HCC tissues (p RITA levels were associated with tumor differentiation status. Overexpression of RITA suppressed cell proliferation and promoted early apoptosis, while its silencing promoted cell growth dramatically (p RITA overexpression upregulated p53 and reduced cyclin E levels, whereas silencing of RITA had the opposite effect on p53 and cyclin E expression. Our in vitro results represent the first evidence that RITA might suppress tumor growth and induce apoptosis in HCCs, and may be a potent antitumoral agent for HCC treatment that deserves further exploration.

  10. Deficiency of RITA results in multiple mitotic defects by affecting microtubule dynamics.

    Science.gov (United States)

    Steinhäuser, K; Klöble, P; Kreis, N-N; Ritter, A; Friemel, A; Roth, S; Reichel, J M; Michaelis, J; Rieger, M A; Louwen, F; Oswald, F; Yuan, J

    2017-04-01

    Deregulation of mitotic microtubule (MT) dynamics results in defective spindle assembly and chromosome missegregation, leading further to chromosome instability, a hallmark of tumor cells. RBP-J interacting and tubulin-associated protein (RITA) has been identified as a negative regulator of the Notch signaling pathway. Intriguingly, deregulated RITA is involved in primary hepatocellular carcinoma and other malignant entities. We were interested in the potential molecular mechanisms behind its involvement. We show here that RITA binds to tubulin and localizes to various mitotic MT structures. RITA coats MTs and affects their structures in vitro as well as in vivo. Tumor cell lines deficient of RITA display increased acetylated α-tubulin, enhanced MT stability and reduced MT dynamics, accompanied by multiple mitotic defects, including chromosome misalignment and segregation errors. Re-expression of wild-type RITA, but not RITA Δtub ineffectively binding to tubulin, restores the phenotypes, suggesting that the role of RITA in MT modulation is mediated via its interaction with tubulin. Mechanistically, RITA interacts with tubulin/histone deacetylase 6 (HDAC6) and its suppression decreases the binding of the deacetylase HDAC6 to tubulin/MTs. Furthermore, the mitotic defects and increased MT stability are also observed in RITA -/- mouse embryonic fibroblasts. RITA has thus a novel role in modulating MT dynamics and its deregulation results in erroneous chromosome segregation, one of the major reasons for chromosome instability in tumor cells.

  11. Preservation of and Permanent Access to Electronic Information Resources

    National Research Council Canada - National Science Library

    Hodge, Gail

    2004-01-01

    The rapid growth in the creation and dissemination of electronic information has emphasized the digital environment's speed and ease of dissemination with little regard for its long-term preservation and access...

  12. Electronic conferencing for continuing medical education: a resource survey.

    Science.gov (United States)

    Sternberg, R J

    1986-10-01

    The use of electronic technologies to link participants for education conferences is an option for providers of Continuing Medical Education. In order to profile the kinds of electronic networks currently offering audio- or videoteleconferences for physician audiences, a survey was done during late 1985. The information collected included range of services, fees, and geographic areas served. The results show a broad diversity of providers providing both interactive and didactic programming to both physicians and other health care professionals.

  13. Controlling user access to electronic resources without password

    Science.gov (United States)

    Smith, Fred Hewitt

    2017-08-22

    Described herein are devices and techniques for remotely controlling user access to a restricted computer resource. The process includes obtaining an image from a communication device of a user. An individual and a landmark are identified within the image. Determinations are made that the individual is the user and that the landmark is a predetermined landmark. Access to a restricted computing resource is granted based on the determining that the individual is the user and that the landmark is the predetermined landmark. Other embodiments are disclosed.

  14. Electron beam pasteurised oil palm waste: a potential feed resource

    International Nuclear Information System (INIS)

    Mat Rasol Awang; Hassan Hamdani Mutaat; Tamikazu Kume; Tachibana, H.

    2002-01-01

    Pasteurization of oil palm empty fruit bunch (EFB) was performed using electron beam single sided irradiation. The dose profiles of oil palm EFB samples for different thickness in both directions X and Y were established. The results showed the usual characteristics dose uniformity as sample thickness decreased. The mean average absorbed dose on both sides at the surface and bottom of the samples for different thickness samples lead to establishing depth dose curve. Based on depth dose curve and operation conditions of electron beam machine, the process throughput for pasteurized oil palm EFB were estimated. (Author)

  15. Santa Rita Experimental Range digital database: user's guide

    Science.gov (United States)

    Mitchel P. McClaran; Deborah L. Angell; Craig Wissler

    2002-01-01

    Long-term measurements and repeat photograph collections have been collected in a systematic manner on the approximately 21,000 ha Santa Rita Experimental Range (SRER) since its establishment in 1903. This research facility, located in the Desert Grassland vegetation of southern Arizona, was administered by the U.S. Department of Agriculture until 1988, when it was...

  16. Swamp tours in Louisiana post Hurricane Katrina and Hurricane Rita

    Science.gov (United States)

    Dawn J. Schaffer; Craig A. Miller

    2007-01-01

    Hurricanes Katrina and Rita made landfall in southern Louisiana during August and September 2005. Prior to these storms, swamp tours were a growing sector of nature-based tourism that entertained visitors while teaching about local flora, fauna, and culture. This study determined post-hurricane operating status of tours, damage sustained, and repairs made. Differences...

  17. Sir John and Lady Rita Cornforth: a distinguished chemical partnership.

    Science.gov (United States)

    Purchase, Rupert; Hanson, James R

    2015-01-01

    This review describes the life of Sir John Cornforth AC CBE FRS, who was awarded the Nobel Prize for Chemistry in 1975. It covers his early life in Australia, his work in Oxford, the National Institute for Medical Research, the Milstead Laboratory of Chemical Enzymology and the University of Sussex, together with the contributions made by his wife, Lady Rita Cornforth.

  18. Resilience of Professional Counselors Following Hurricanes Katrina and Rita

    Science.gov (United States)

    Lambert, Simone F.; Lawson, Gerard

    2013-01-01

    Professional counselors who provided services to those affected by Hurricanes Katrina and Rita completed the K6+ (screen for severe mental illness), the Posttraumatic Growth Inventory, and the Professional Quality of Life Scale. Results indicated that participants who survived the hurricanes had higher levels of posttraumatic growth than…

  19. Availability of Electronic Resources for Service Provision in ...

    African Journals Online (AJOL)

    The study also revealed that majority of the University libraries have adequate basic infrastructure for effective electronic information services. ... acquired by the library are put into maximal use by the library clientele, thereby ensuring the achievement of the library's objective which is satisfying the users, information needs.

  20. Utilization of bio-resources by low energy electron beam

    International Nuclear Information System (INIS)

    Kume, Tamikazu

    2003-01-01

    Utilization of bio-resources by radiation has been investigated for recycling the natural resources and reducing the environmental pollution. Polysaccharides such as chitosan and sodium alginate were easily degraded by irradiation and induced various kinds of biological activities, i.g. anti-microbial activity, promotion of plant growth, suppression of heavy metal stress, phytoalexins induction. Radiation degraded chitosan was effective to enhance the growth of plants in tissue culture. It was demonstrated that the liquid sample irradiation system using low energy EB was effective for the preparation of degraded polysaccharides. Methylcellulose (MC) can be crosslinked under certain radiation condition as same as carboxymethylcellulose (CMC) and produced the biodegradable hydrogel for medical and agricultural use. Treatment of soybean seeds by low energy EB enhanced the growth and the number of rhizobia on the root. (author)

  1. Analysis of the interaction between human RITA and Drosophila Suppressor of Hairless.

    Science.gov (United States)

    Brockmann, Birgit; Mastel, Helena; Oswald, Franz; Maier, Dieter

    2014-12-01

    Notch signalling mediates intercellular communication, which is effected by the transcription factor CSL, an acronym for vertebrate CBF1/RBP-J, Drosophila Suppressor of Hairless [Su(H)] and C. elegans Lag1. Nuclear import of CBF1/RBP-J depends on co-activators and co-repressors, whereas the export relies on RITA. RITA is a tubulin and CBF1/RBP-J binding protein acting as a negative regulator of Notch signalling in vertebrates. RITA protein is highly conserved in eumatazoa, but no Drosophila homologue was yet identified. In this work, the activity of human RITA in the fly was addressed. To this end, we generated transgenic flies that allow a tissue specific induction of human RITA, which was demonstrated by Western blotting and in fly tissues. Unexpectedly, overexpression of RITA during fly development had little phenotypic consequences, even when overexpressed simultaneously with either Su(H) or the Notch antagonist Hairless. We demonstrate the in vivo binding of human RITA to Su(H) and to tubulin by co-immune precipitation. Moreover, RITA and tubulin co-localized to some degree in several Drosophila tissues. Overall our data show that human RITA, albeit binding to Drosophila Su(H) and tubulin, cannot influence the Notch signalling pathway in the fly, suggesting that a nuclear export mechanism of Su(H), if existent in Drosophila, does not depend on RITA. © 2015 The Authors.

  2. Analysis of Pedagogic Potential of Electronic Educational Resources with Elements of Autodidactics

    Directory of Open Access Journals (Sweden)

    Igor A.

    2018-03-01

    Full Text Available Introduction: in recent years didactic properties of electronic educational resources undergo considerable changes, nevertheless, the question of studying of such complete phenomenon as “an electronic educational resource with autodidactics elements” remains open, despite sufficient scientific base of researches of the terms making this concept. Article purpose – determination of essence of electronic educational resources with autodidactics elements. Materials and Methods: the main method of research was the theoretical analysis of the pedagogical and psychological literature on the problem under study. We used the theoretical (analysis, synthesis, comparison and generalization methods, the method of interpretation, pedagogical modeling, and empirical methods (observation, testing, conversation, interview, analysis of students’ performance, pedagogical experiment, peer review. Results: we detected the advantages of electronic educational resources in comparison with traditional ones. The concept of autodidactics as applied to the subject of research is considered. Properties of electronic educational resources with a linear and nonlinear principle of construction are studied.The influence of the principle of construction on the development of the learners’ qualities is shown. We formulated an integral definition of electronic educational resources with elements of autodidactics, namely, the variability, adaptivity and cyclicity of training. A model of the teaching-learning process with electronic educational resources is developed. Discussion and Conclusions: further development of a problem will allow to define whether electronic educational resources with autodidactics elements pedagogical potential for realization of educational and self-educational activity of teachers have, to modify technological procedures taking into account age features of students, their specialties and features of the organization of process of training of

  3. Surface ultrastructure of the gill filaments and the secondary lamellae of the catfish, Rita rita, and the carp, Cirrhinus mrigala.

    Science.gov (United States)

    Kumari, Usha; Mittal, Swati; Mittal, Ajay Kumar

    2012-04-01

    Surface ultrastructures of gill filaments and secondary lamellae of Rita rita and Cirrhinus mrigala, inhabiting different ecological habitat, were investigated to unravel adaptive modifications. R. rita is a sluggish, bottom dwelling carnivorous catfish, which inhabits regions of river with accumulations of dirty water. It retains its viability for long time if taken out of water. C. mrigala is an active bottom dwelling Indian major carp, which lives in relatively clean water and dies shortly after taken out of water. In R. rita, gill septa between gill filaments are reduced. Microridges on epithelial cells covering gill filaments are often continuous and arranged concentrically. Secondary lamellae are extensive. The epithelium appears corrugated, show irregular elevations and shallow depressions, and microridges on epithelial cells appear fragmented. In C. mrigala, in contrast, the gill septa are extensive. Microridges on epithelial cells covering gill filaments are fragmented. Secondary lamellae are less extensive. The epithelium appears smooth and microridges on epithelial cells are relatively inconspicuous. These differences have been considered adaptive modification in relation to habit and ecological niches inhabited by two fish species. Presence of mucous goblet cells on gill filaments is discussed in relation to their functions including precipitation of the sediments and preventing clogging of gill filaments. Infrequent mucous goblet cells in the epithelium of secondary lamellae in two fish species are considered an adaptation, minimizing thickness of the epithelium to reduce barrier between blood and water for favoring gasses exchange with increased efficiency. Copyright © 2011 Wiley-Liss, Inc.

  4. Serous goblet cells: the protein secreting cells in the oral cavity of a catfish, Rita rita (Hamilton, 1822) (Bagridae, Siluriformes).

    Science.gov (United States)

    Yashpal, Madhu; Mittal, Ajay Kumar

    2014-02-01

    Serous goblet cells in the oral epithelium of Rita rita are characterized by the presence of distinct eosinophilic granules occupying large parts of the cytoplasm. In R. rita, a range of histochemical results reveal that these cells are involved in proteinaceous secretions, and thus likely contribute to various functions analogous to those of mammalian saliva. The secretions of these cells have also been associated with specific functions and are discussed in relation to their physiological importance with special reference to their roles in lubrication, alteration in viscosity, various functions of mucus such as handling, maneuvering and driving of food items toward the esophagus, maintaining taste sensitivity and protection of the oral epithelium. In addition, the serous goblet cells may also be considered as the primary defensive cell of the oral epithelium of R. rita. The results significantly add to very limited set of literature on the serous goblet cells and provide noteworthy information on the mucous secretions in the oral cavity of fish. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. A Study on Developing Evaluation Criteria for Electronic Resources in Evaluation Indicators of Libraries

    Science.gov (United States)

    Noh, Younghee

    2010-01-01

    This study aimed to improve the current state of electronic resource evaluation in libraries. While the use of Web DB, e-book, e-journal, and other e-resources such as CD-ROM, DVD, and micro materials is increasing in libraries, their use is not comprehensively factored into the general evaluation of libraries and may diminish the reliability of…

  6. Managing Selection for Electronic Resources: Kent State University Develops a New System to Automate Selection

    Science.gov (United States)

    Downey, Kay

    2012-01-01

    Kent State University has developed a centralized system that manages the communication and work related to the review and selection of commercially available electronic resources. It is an automated system that tracks the review process, provides selectors with price and trial information, and compiles reviewers' feedback about the resource. It…

  7. Where Do Electronic Books Fit in the College Research Arsenal of Resources?

    Science.gov (United States)

    Barbier, Patricia

    2007-01-01

    Student use of electronic books has become an accepted supplement to traditional resources. Student use and satisfaction was monitored through an online course discussion board. Increased use of electronic books indicate this service is an accepted supplement to the print book collection.

  8. A Prospective Study of Religiousness and Psychological Distress Among Female Survivors of Hurricanes Katrina and Rita

    Science.gov (United States)

    Rhodes, Jean E.; Pérez, John E.

    2013-01-01

    This prospective study examined the pathways by which religious involvement affected the post-disaster psychological functioning of women who survived Hurricanes Katrina and Rita. The participants were 386 low-income, predominantly Black, single mothers. The women were enrolled in the study before the hurricane, providing a rare opportunity to document changes in mental health from before to after the storm, and to assess the protective role of religious involvement over time. Results of structural equation modeling indicated that, controlling for level of exposure to the hurricanes, pre-disaster physical health, age, and number of children, pre-disaster religiousness predicted higher levels of post-disaster (1) social resources and (2) optimism and sense of purpose. The latter, but not the former, was associated with better post-disaster psychological outcome. Mediation analysis confirmed the mediating role of optimism and sense of purpose. PMID:21626083

  9. A prospective study of religiousness and psychological distress among female survivors of Hurricanes Katrina and Rita.

    Science.gov (United States)

    Chan, Christian S; Rhodes, Jean E; Pérez, John E

    2012-03-01

    This prospective study examined the pathways by which religious involvement affected the post-disaster psychological functioning of women who survived Hurricanes Katrina and Rita. The participants were 386 low-income, predominantly Black, single mothers. The women were enrolled in the study before the hurricane, providing a rare opportunity to document changes in mental health from before to after the storm, and to assess the protective role of religious involvement over time. Results of structural equation modeling indicated that, controlling for level of exposure to the hurricanes, pre-disaster physical health, age, and number of children, pre-disaster religiousness predicted higher levels of post-disaster (1) social resources and (2) optimism and sense of purpose. The latter, but not the former, was associated with better post-disaster psychological outcome. Mediation analysis confirmed the mediating role of optimism and sense of purpose.

  10. The National Site Licensing of Electronic Resources: An Institutional Perspective

    Directory of Open Access Journals (Sweden)

    Xiaohua Zhu

    2011-06-01

    Full Text Available While academic libraries in most countries are struggling to negotiate with publishers and vendors individually or collaboratively via consortia, a few countries have experimented with a different model, national site licensing (NSL. Because NSL often involves government and large-scale collaboration, it has the potential to solve many problems in the complex licensing world. However, not many nations have adopted it. This study uses historical research approach and the comparative case study research method to explore the seemingly low level of adoption. The cases include the Canadian National Site Licensing Project (CNSLP, the United Kingdom’s National Electronic Site Licensing Initiative (NESLI, and the United States, which has not adopted NSL. The theoretical framework guiding the research design and data collection is W. Richard Scott’s institutional theory, which utilizes three supporting pillars—regulative, normative, and cultural-cognitive—to analyze institutional processes. In this study, the regulative pillar and the normative pillar of NSL adoption— an institutional construction and change—are examined. Data were collected from monographs, research articles, government documents, and relevant websites. Based on the analysis of these cases, a preliminary model is proposed for the adoption of NSL. The factors that support a country’s adoption of NSL include the need for new institutions, a centralized educational policy-making system and funding system, supportive political trends, and the tradition of cooperation. The factors that may prevent a country from adopting NSL include decentralized educational policy and funding, diversity and the large number of institutions, the concern for the “Big Deal,” and the concern for monopoly.

  11. Combined VLF and VHF lightning observations of Hurricane Rita landfall

    Science.gov (United States)

    Henderson, B. G.; Suszcynsky, D. M.; Wiens, K. C.; Hamlin, T.; Jeffery, C. A.; Orville, R. E.

    2009-12-01

    Hurricane Rita displayed abundant lightning in its northern eyewall as it made landfall at 0740 UTC 24 Sep 2005 near the Texas/Louisiana border. For this work, we combined VHF and VLF lightning data from Hurricane Rita, along with radar observations from Gulf Coast WSR-88D stations, for the purpose of demonstrating the combined utility of these two spectral regions for hurricane lightning monitoring. Lightning is a direct consequence of the electrification and breakdown processes that take place during the convective stages of thunderstorm development. As Rita approached the Gulf coast, the VHF lightning emissions were distinctly periodic with a period of 1.5 to 2 hours, which is consistent with the rotational period of hurricanes. VLF lightning emissions, measured by LASA and NLDN, were present in some of these VHF bursts but not all of them. At landfall, there was a significant increase in lightning emissions, accompanied by a significant convective surge observed in radar. Furthermore, VLF and VHF lightning source heights clearly increase as a function of time. The evolution of the IC/CG ratio is consistent with that seen in thunderstorms, showing a dominance of IC activity during storm development, followed by an increase in CG activity at the storm’s peak. The periodic VHF lightning events are correlated with increases in convective growth (quantified by the volume of radar echo >40 dB) above 7 km altitude. VLF can discriminate between lightning types, and in the LASA data, Rita landfall lightning activity was dominated by Narrow Bi-polar Events (NBEs)—high-energy, high-altitude, compact intra-cloud discharges. The opportunity to locate NBE lightning sources in altitude may be particularly useful in quantifying the vertical extent (strength) of the convective development and in possibly deducing vertical charge distributions.

  12. Lightning and radar observations of hurricane Rita landfall

    Energy Technology Data Exchange (ETDEWEB)

    Henderson, Bradley G [Los Alamos National Laboratory; Suszcynsky, David M [Los Alamos National Laboratory; Hamlin, Timothy E [Los Alamos National Laboratory; Jeffery, C A [Los Alamos National Laboratory; Wiens, Kyle C [TEXAS TECH U.; Orville, R E [TEXAS A& M

    2009-01-01

    Los Alamos National Laboratory (LANL) owns and operates an array of Very-Low Frequency (VLF) sensors that measure the Radio-Frequency (RF) waveforms emitted by Cloud-to-Ground (CG) and InCloud (IC) lightning. This array, the Los Alamos Sferic Array (LASA), has approximately 15 sensors concentrated in the Great Plains and Florida, which detect electric field changes in a bandwidth from 200 Hz to 500 kHz (Smith et al., 2002). Recently, LANL has begun development of a new dual-band RF sensor array that includes the Very-High Frequency (VHF) band as well as the VLF. Whereas VLF lightning emissions can be used to deduce physical parameters such as lightning type and peak current, VHF emissions can be used to perform precise 3d mapping of individual radiation sources, which can number in the thousands for a typical CG flash. These new dual-band sensors will be used to monitor lightning activity in hurricanes in an effort to better predict intensification cycles. Although the new LANL dual-band array is not yet operational, we have begun initial work utilizing both VLF and VHF lightning data to monitor hurricane evolution. In this paper, we present the temporal evolution of Rita's landfall using VLF and VHF lightning data, and also WSR-88D radar. At landfall, Rita's northern eyewall experienced strong updrafts and significant lightning activity that appear to mark a transition between oceanic hurricane dynamics and continental thunderstorm dynamics. In section 2, we give a brief overview of Hurricane Rita, including its development as a hurricane and its lightning history. In the following section, we present WSR-88D data of Rita's landfall, including reflectivity images and temporal variation. In section 4, we present both VHF and VLF lightning data, overplotted on radar reflectivity images. Finally, we discuss our observations, including a comparison to previous studies and a brief conclusion.

  13. A survey of the use of electronic scientific information resources among medical and dental students

    Directory of Open Access Journals (Sweden)

    Aarnio Matti

    2006-05-01

    Full Text Available Abstract Background To evaluate medical and dental students' utilization of electronic information resources. Methods A web survey sent to 837 students (49.9% responded. Results Twenty-four per cent of medical students and ninteen per cent of dental students searched MEDLINE 2+ times/month for study purposes, and thiry-two per cent and twenty-four per cent respectively for research. Full-text articles were used 2+ times/month by thirty-three per cent of medical and ten per cent of dental students. Twelve per cent of respondents never utilized either MEDLINE or full-text articles. In multivariate models, the information-searching skills among students were significantly associated with use of MEDLINE and full-text articles. Conclusion Use of electronic resources differs among students. Forty percent were non-users of full-text articles. Information-searching skills are correlated with the use of electronic resources, but the level of basic PC skills plays not a major role in using these resources. The student data shows that adequate training in information-searching skills will increase the use of electronic information resources.

  14. Analytical Study of Usage of Electronic Information Resources at Pharmacopoeial Libraries in India

    Directory of Open Access Journals (Sweden)

    Sunil Tyagi

    2014-02-01

    Full Text Available The objective of this study is to know the rate and purpose of the use of e-resource by the scientists at pharmacopoeial libraries in India. Among other things, this study examined the preferences of the scientists toward printed books and journals, electronic information resources, and pattern of using e-resources. Non-probability sampling specially accidental and purposive technique was applied in the collection of primary data through administration of user questionnaire. The sample respondents chosen for the study consists of principle scientific officer, senior scientific officer, scientific officer, and scientific assistant of different division of the laboratories, namely, research and development, pharmaceutical chemistry, pharmacovigilance, pharmacology, pharmacogonosy, and microbiology. The findings of the study reveal the personal experiences and perceptions they have had on practice and research activity using e-resource. The major findings indicate that of the total anticipated participants, 78% indicated that they perceived the ability to use computer for electronic information resources. The data analysis shows that all the scientists belonging to the pharmacopoeial libraries used electronic information resources to address issues relating to drug indexes and compendia, monographs, drugs obtained through online databases, e-journals, and the Internet sources—especially polices by regulatory agencies, contacts, drug promotional literature, and standards.

  15. 75 FR 7467 - Gary E. Hall and Rita C. Hall; Notice of Application Accepted for Filing With the Commision...

    Science.gov (United States)

    2010-02-19

    ... Rita C. Hall; Notice of Application Accepted for Filing With the Commision, Soliciting Motions To.... Project No.: 13652-000. c. Date filed: January 11, 2010. d. Applicant: Gary E. Hall and Rita C. Hall. e... Policies Act of 1978, 16 U.S.C. 2705, 2708. h. Applicant Contact: Mr. Gary E. Hall and Ms. Rita C. Hall, P...

  16. RITA plus 3-MA overcomes chemoresistance of head and neck cancer cells via dual inhibition of autophagy and antioxidant systems

    Directory of Open Access Journals (Sweden)

    Daiha Shin

    2017-10-01

    Condensed abstract: This study revealed a novel RITA resistant mechanism associated with the sustained induction of autophagy, p62 overexpression, and Keap1-Nrf2 antioxidant system activation. The combined treatment of RITA with the autophagy inhibitor 3-methyladenine overcomes RITA resistance via dual inhibition of autophagy and antioxidant systems in vitro and in vivo.

  17. Considering Point-of-Care Electronic Medical Resources in Lieu of Traditional Textbooks for Medical Education.

    Science.gov (United States)

    Hale, LaDonna S; Wallace, Michelle M; Adams, Courtney R; Kaufman, Michelle L; Snyder, Courtney L

    2015-09-01

    Selecting resources to support didactic courses is a critical decision, and the advantages and disadvantages must be carefully considered. During clinical rotations, students not only need to possess strong background knowledge but also are expected to be proficient with the same evidence-based POC resources used by clinicians. Students place high value on “real world” learning and therefore may place more value on POC resources that they know practicing clinicians use as compared with medical textbooks. The condensed nature of PA education requires students to develop background knowledge and information literacy skills over a short period. One way to build that knowledge and those skills simultaneously is to use POC resources in lieu of traditional medical textbooks during didactic training. Electronic POC resources offer several advantages over traditional textbooks and should be considered as viable options in PA education.

  18. Elektronik Bilgi Kaynaklarının Seçimi / Selection of Electronic Information Resources

    Directory of Open Access Journals (Sweden)

    Pınar Al

    2003-04-01

    Full Text Available For many years, library users have used only from the printed media in order to get the information that they have needed. Today with the widespread use of the Web and the addition of electronic information resources to library collections, the use of information in the electronic environment as well as in printed media is started to be used. In time, such types of information resources as, electronic journals, electronic books, electronic encyclopedias, electronic dictionaries and electronic theses have been added to library collections. In this study, selection criteria that can be used for electronic information resources are discussed and suggestions are provided for libraries that try to select electronic information resources for their collections.

  19. The p53-reactivating small molecule RITA induces senescence in head and neck cancer cells.

    Directory of Open Access Journals (Sweden)

    Hui-Ching Chuang

    Full Text Available TP53 is the most commonly mutated gene in head and neck cancer (HNSCC, with mutations being associated with resistance to conventional therapy. Restoring normal p53 function has previously been investigated via the use of RITA (reactivation of p53 and induction of tumor cell apoptosis, a small molecule that induces a conformational change in p53, leading to activation of its downstream targets. In the current study we found that RITA indeed exerts significant effects in HNSCC cells. However, in this model, we found that a significant outcome of RITA treatment was accelerated senescence. RITA-induced senescence in a variety of p53 backgrounds, including p53 null cells. Also, inhibition of p53 expression did not appear to significantly inhibit RITA-induced senescence. Thus, this phenomenon appears to be partially p53-independent. Additionally, RITA-induced senescence appears to be partially mediated by activation of the DNA damage response and SIRT1 (Silent information regulator T1 inhibition, with a synergistic effect seen by combining either ionizing radiation or SIRT1 inhibition with RITA treatment. These data point toward a novel mechanism of RITA function as well as hint to its possible therapeutic benefit in HNSCC.

  20. How Schools Responded to Student Mental Health Needs Following Hurricanes Katrina and Rita. Fact Sheet

    Science.gov (United States)

    RAND Corporation, 2007

    2007-01-01

    This fact sheet summarizes a study that examined how schools in the U.S. Gulf Coast region perceived the mental health needs of students after Hurricanes Katrina and Rita and how schools responded. According to the report, despite strong initial efforts to support the mental health needs of students displaced by Hurricanes Katrina and Rita, many…

  1. The p53-reactivating small molecule RITA induces senescence in head and neck cancer cells.

    Science.gov (United States)

    Chuang, Hui-Ching; Yang, Liang Peng; Fitzgerald, Alison L; Osman, Abdullah; Woo, Sang Hyeok; Myers, Jeffrey N; Skinner, Heath D

    2014-01-01

    TP53 is the most commonly mutated gene in head and neck cancer (HNSCC), with mutations being associated with resistance to conventional therapy. Restoring normal p53 function has previously been investigated via the use of RITA (reactivation of p53 and induction of tumor cell apoptosis), a small molecule that induces a conformational change in p53, leading to activation of its downstream targets. In the current study we found that RITA indeed exerts significant effects in HNSCC cells. However, in this model, we found that a significant outcome of RITA treatment was accelerated senescence. RITA-induced senescence in a variety of p53 backgrounds, including p53 null cells. Also, inhibition of p53 expression did not appear to significantly inhibit RITA-induced senescence. Thus, this phenomenon appears to be partially p53-independent. Additionally, RITA-induced senescence appears to be partially mediated by activation of the DNA damage response and SIRT1 (Silent information regulator T1) inhibition, with a synergistic effect seen by combining either ionizing radiation or SIRT1 inhibition with RITA treatment. These data point toward a novel mechanism of RITA function as well as hint to its possible therapeutic benefit in HNSCC.

  2. Te Rita Papesch: Case Study of an Exemplary Learner of Maori as an Additional Language

    Science.gov (United States)

    Ratima, Matiu Tai; Papesch, Te Rita

    2014-01-01

    This paper presents a case study of the life experiences of one exemplar adult second language Maori learner--Te Rita Papesch. Te Rita was one of 17 participants who were interviewed as a part of the first author's PhD study which sought to answer the question: what factors lead to the development of proficiency in te reo Maori amongst adult…

  3. 75 FR 14442 - Federal Travel Regulation (FTR); Relocation Allowances-Relocation Income Tax Allowance (RITA) Tables

    Science.gov (United States)

    2010-03-25

    ... GENERAL SERVICES ADMINISTRATION [GSA Bulletin FTR 10-04] Federal Travel Regulation (FTR); Relocation Allowances-- Relocation Income Tax Allowance (RITA) Tables AGENCY: Office of Governmentwide Policy... (73 FR 35952) specifying that GSA would no longer publish the RITA tables found in 41 CFR Part 301-17...

  4. The burden of rare cancers in Italy: the surveillance of rare cancers in Italy (RITA) project.

    Science.gov (United States)

    Trama, Annalisa; Mallone, Sandra; Ferretti, Stefano; Meduri, Francesca; Capocaccia, Riccardo; Gatta, Gemma

    2012-01-01

    The project Surveillance of rare cancers in Italy (RITA) provides, for the first time, estimates of the burden of rare cancers in Italy based on the list of rare cancers proposed in collaboration with the European project Surveillance of Rare Cancers in Europe (RARECARE). RITA analyzed data from Italian population-based cancer registries (CR). The period of diagnosis was 1988 to 2002, and vital status information was available up to December 31, 2003. Incidence rates were estimated for the period 1995-2002, survival for the years 2000-2002 (with the period method of Brenner), and complete prevalence at January 1, 2003. Rare cancers are those with an incidence <6/100,000/year. In Italy, every year there are 60,000 new diagnoses of rare cancers corresponding to 15% of all new cancer diagnoses. Five-year relative survival was on the average worse for rare cancers (53%) than for common cancers (73%). A total of 770,000 patients were living in Italy in 2008 with a diagnosis of a rare cancer, 22% of the total cancer prevalence. Our estimates constitute a useful base for further research and support the idea that rare cancers are a public health problem that deserves attention. Centers of expertise for rare cancers that pool cases, expertise and resources could ensure an adequate clinical management for these diseases. Our data also showed that cancer registries are suitable sources of data to estimate incidence, prevalence and survival for rare cancers and should continue to monitoring rare cancers in Italy.

  5. Use of electronic sales data to tailor nutrition education resources for an ethnically diverse population.

    Science.gov (United States)

    Eyles, H; Rodgers, A; Ni Mhurchu, C

    2010-02-01

    Nutrition education may be most effective when personally tailored. Individualised electronic supermarket sales data offer opportunities to tailor nutrition education using shopper's usual food purchases. The present study aimed to use individualised electronic supermarket sales data to tailor nutrition resources for an ethnically diverse population in a large supermarket intervention trial in New Zealand. Culturally appropriate nutrition education resources (i.e. messages and shopping lists) were developed with the target population (through two sets of focus groups) and ethnic researchers. A nutrient database of supermarket products was developed using retrospective sales data and linked to participant sales to allow tailoring by usual food purchases. Modified Heart Foundation Tick criteria were used to identify 'healthier' products in the database suitable for promotion in the resources. Rules were developed to create a monthly report listing the tailored and culturally targeted messages to be sent to each participant, and to produce automated, tailored shopping lists. Culturally targeted nutrition messages (n = 864) and shopping lists (n = 3 formats) were developed. The food and nutrient database (n = 3000 top-selling products) was created using 12 months of retrospective sales data, and comprised 60%'healthier' products. Three months of baseline sales data were used to determine usual food purchases. Tailored resources were successfully mailed to 123 Māori, 52 Pacific and 346 non-Māori non-Pacific participants over the 6-month trial intervention period. Electronic supermarket sales data can be used to tailor nutrition education resources for a large number of ethnically diverse supermarket shoppers.

  6. RITA displays anti-tumor activity in medulloblastomas independent of TP53 status.

    Science.gov (United States)

    Gottlieb, Aline; Althoff, Kristina; Grunewald, Laura; Thor, Theresa; Odersky, Andrea; Schulte, Marc; Deubzer, Hedwig E; Heukamp, Lukas; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes H; Künkele, Annette

    2017-04-25

    Current therapy of medulloblastoma, the most common malignant brain tumor of childhood, achieves 40-70% survival. Secondary chemotherapy resistance contributes to treatment failure, where TP53 pathway dysfunction plays a key role. MDM2 interaction with TP53 leads to its degradation. Reactivating TP53 functionality using small-molecule inhibitors, such as RITA, to disrupt TP53-MDM2 binding may have therapeutic potential. We show here that RITA decreased viability of all 4 analyzed medulloblastoma cell lines, regardless of TP53 functional status. The decrease in cell viability was accompanied in 3 of the 4 medulloblastoma cell lines by accumulation of TP53 protein in the cells and increased CDKN1A expression. RITA treatment in mouse models inhibited medulloblastoma xenograft tumor growth. These data demonstrate that RITA treatment reduces medulloblastoma cell viability in both in vitro and in vivo models, and acts independently of cellular TP53 status, identifying RITA as a potential therapeutic agent to treat medulloblastoma.

  7. Conversacion sobre "Tres tristes tigres". Una entrevista de Rita Guibert (A Conversation about "Three Sad Tigers". An Interview with Rita Guibert)

    Science.gov (United States)

    Cabrera Infante, Guillermo

    1971-01-01

    Interview took place in London, England, on October 5, 1970 between Cuban writer Guillermo Cabrera Infante and journalist Rita Guibert. Special issue dedicated to contemporary Spanish American literature. (DS)

  8. REVIEW OF MOODLE PLUGINS FOR DESIGNING MULTIMEDIA ELECTRONIC EDUCATIONAL RESOURCES FROM LANGUAGE DISCIPLINES

    Directory of Open Access Journals (Sweden)

    Anton M. Avramchuk

    2015-09-01

    Full Text Available Today the problem of designing multimedia electronic educational resources from language disciplines in Moodle is very important. This system has a lot of different, powerful resources, plugins to facilitate the learning of students with language disciplines. This article presents an overview and comparative analysis of the five Moodle plugins for designing multimedia electronic educational resources from language disciplines. There have been considered their key features and functionality in order to choose the best for studying language disciplines in the Moodle. Plugins are compared by a group of experts according to the criteria: efficiency, functionality and easy use. For a comparative analysis of the plugins it is used the analytic hierarchy process.

  9. Reactivating p53 and Inducing Tumor Apoptosis (RITA) Enhances the Response of RITA-Sensitive Colorectal Cancer Cells to Chemotherapeutic Agents 5-Fluorouracil and Oxaliplatin.

    Science.gov (United States)

    Wiegering, Armin; Matthes, Niels; Mühling, Bettina; Koospal, Monika; Quenzer, Anne; Peter, Stephanie; Germer, Christoph-Thomas; Linnebacher, Michael; Otto, Christoph

    2017-04-01

    Colorectal carcinoma (CRC) is the most common cancer of the gastrointestinal tract with frequently dysregulated intracellular signaling pathways, including p53 signaling. The mainstay of chemotherapy treatment of CRC is 5-fluorouracil (5FU) and oxaliplatin. The two anticancer drugs mediate their therapeutic effect via DNA damage-triggered signaling. The small molecule reactivating p53 and inducing tumor apoptosis (RITA) is described as an activator of wild-type and reactivator of mutant p53 function, resulting in elevated levels of p53 protein, cell growth arrest, and cell death. Additionally, it has been shown that RITA can induce DNA damage signaling. It is expected that the therapeutic benefits of 5FU and oxaliplatin can be increased by enhancing DNA damage signaling pathways. Therefore, we highlighted the antiproliferative response of RITA alone and in combination with 5FU or oxaliplatin in human CRC cells. A panel of long-term established CRC cell lines (n=9) including p53 wild-type, p53 mutant, and p53 null and primary patient-derived, low-passage cell lines (n=5) with different p53 protein status were used for this study. A substantial number of CRC cells with pronounced sensitivity to RITA (IC 50 RITA appeared independent of p53 status and was associated with an increase in antiproliferative response to 5FU and oxaliplatin, a transcriptional increase of p53 targets p21 and NOXA, and a decrease in MYC mRNA. The effect of RITA as an inducer of DNA damage was shown by a strong elevation of phosphorylated histone variant H2A.X, which was restricted to RITA-sensitive cells. Our data underline the primary effect of RITA, inducing DNA damage, and demonstrate the differential antiproliferative effect of RITA to CRC cells independent of p53 protein status. We found a substantial number of RITA-sensitive CRC cells within both panels of established CRC cell lines and primary patient-derived CRC cell lines (6/14) that provide a rationale for combining RITA with 5FU or

  10. Reactivating p53 and Inducing Tumor Apoptosis (RITA Enhances the Response of RITA-Sensitive Colorectal Cancer Cells to Chemotherapeutic Agents 5-Fluorouracil and Oxaliplatin

    Directory of Open Access Journals (Sweden)

    Armin Wiegering

    2017-04-01

    Full Text Available Colorectal carcinoma (CRC is the most common cancer of the gastrointestinal tract with frequently dysregulated intracellular signaling pathways, including p53 signaling. The mainstay of chemotherapy treatment of CRC is 5-fluorouracil (5FU and oxaliplatin. The two anticancer drugs mediate their therapeutic effect via DNA damage-triggered signaling. The small molecule reactivating p53 and inducing tumor apoptosis (RITA is described as an activator of wild-type and reactivator of mutant p53 function, resulting in elevated levels of p53 protein, cell growth arrest, and cell death. Additionally, it has been shown that RITA can induce DNA damage signaling. It is expected that the therapeutic benefits of 5FU and oxaliplatin can be increased by enhancing DNA damage signaling pathways. Therefore, we highlighted the antiproliferative response of RITA alone and in combination with 5FU or oxaliplatin in human CRC cells. A panel of long-term established CRC cell lines (n = 9 including p53 wild-type, p53 mutant, and p53 null and primary patient-derived, low-passage cell lines (n = 5 with different p53 protein status were used for this study. A substantial number of CRC cells with pronounced sensitivity to RITA (IC50< 3.0 μmol/l were identified within established (4/9 and primary patient-derived (2/5 CRC cell lines harboring wild-type or mutant p53 protein. Sensitivity to RITA appeared independent of p53 status and was associated with an increase in antiproliferative response to 5FU and oxaliplatin, a transcriptional increase of p53 targets p21 and NOXA, and a decrease in MYC mRNA. The effect of RITA as an inducer of DNA damage was shown by a strong elevation of phosphorylated histone variant H2A.X, which was restricted to RITA-sensitive cells. Our data underline the primary effect of RITA, inducing DNA damage, and demonstrate the differential antiproliferative effect of RITA to CRC cells independent of p53 protein status. We found a substantial number

  11. Effects of the Use of Electronic Human Resource Management (EHRM Within Human Resource Management (HRM Functions at Universities

    Directory of Open Access Journals (Sweden)

    Chux Gervase Iwu

    2016-09-01

    Full Text Available This study set out to examine the effect of e-hrm systems in assisting human resource practitioners to execute their duties and responsibilities. In comparison to developed economies of the world, information technology adoption in sub-Saharan Africa has not been without certain glitches. Some of the factors that are responsible for these include poor need identification, sustainable funding, and insufficient skills. Besides these factors, there is also the issue of change management and users sticking to what they already know. Although, the above factors seem negative, there is strong evidence that information systems such as electronic human resource management present benefits to an organization. To achieve this, a dual research approach was utilized. Literature assisted immensely in both the development of the conceptual framework upon which the study hinged as well as in the development of the questionnaire items. The study also made use of an interview checklist to guide the participants. The findings reveal a mix of responses that indicate that while there are gains in adopting e-hrm systems, it is wiser to consider supporting resources as well as articulate the needs of the university better before any investment is made.

  12. The Electron Microscopy Outreach Program: A Web-based resource for research and education.

    Science.gov (United States)

    Sosinsky, G E; Baker, T S; Hand, G; Ellisman, M H

    1999-01-01

    We have developed a centralized World Wide Web (WWW)-based environment that serves as a resource of software tools and expertise for biological electron microscopy. A major focus is molecular electron microscopy, but the site also includes information and links on structural biology at all levels of resolution. This site serves to help integrate or link structural biology techniques in accordance with user needs. The WWW site, called the Electron Microscopy (EM) Outreach Program (URL: http://emoutreach.sdsc.edu), provides scientists with computational and educational tools for their research and edification. In particular, we have set up a centralized resource containing course notes, references, and links to image analysis and three-dimensional reconstruction software for investigators wanting to learn about EM techniques either within or outside of their fields of expertise. Copyright 1999 Academic Press.

  13. Shelf sediment transport during hurricanes Katrina and Rita

    Science.gov (United States)

    Xu, Kehui; Mickey, Rangley C.; Chen, Qin; Harris, Courtney K.; Hetland, Robert D.; Hu, Kelin; Wang, Jiaze

    2016-05-01

    Hurricanes can greatly modify the sedimentary record, but our coastal scientific community has rather limited capability to predict hurricane-induced sediment deposition. A three-dimensional sediment transport model was developed in the Regional Ocean Modeling System (ROMS) to study seabed erosion and deposition on the Louisiana shelf in response to Hurricanes Katrina and Rita in the year 2005. Sensitivity tests were performed on both erosional and depositional processes for a wide range of erosional rates and settling velocities, and uncertainty analysis was done on critical shear stresses using the polynomial chaos approximation method. A total of 22 model runs were performed in sensitivity and uncertainty tests. Estimated maximum erosional depths were sensitive to the inputs, but horizontal erosional patterns seemed to be controlled mainly by hurricane tracks, wave-current combined shear stresses, seabed grain sizes, and shelf bathymetry. During the passage of two hurricanes, local resuspension and deposition dominated the sediment transport mechanisms. Hurricane Katrina followed a shelf-perpendicular track before making landfall and its energy dissipated rapidly within about 48 h along the eastern Louisiana coast. In contrast, Hurricane Rita followed a more shelf-oblique track and disturbed the seabed extensively during its 84-h passage from the Alabama-Mississippi border to the Louisiana-Texas border. Conditions to either side of Hurricane Rita's storm track differed substantially, with the region to the east having stronger winds, taller waves and thus deeper erosions. This study indicated that major hurricanes can disturb the shelf at centimeter to meter levels. Each of these two hurricanes suspended seabed sediment mass that far exceeded the annual sediment inputs from the Mississippi and Atchafalaya Rivers, but the net transport from shelves to estuaries is yet to be determined. Future studies should focus on the modeling of sediment exchange between

  14. Identifying and evaluating electronic learning resources for use in adult-gerontology nurse practitioner education.

    Science.gov (United States)

    Thompson, Hilaire J; Belza, Basia; Baker, Margaret; Christianson, Phyllis; Doorenbos, Ardith; Nguyen, Huong

    2014-01-01

    Enhancing existing curricula to meet newly published adult-gerontology advanced practice registered nurse (APRN) competencies in an efficient manner presents a challenge to nurse educators. Incorporating shared, published electronic learning resources (ELRs) in existing or new courses may be appropriate in order to assist students in achieving competencies. The purposes of this project were to (a) identify relevant available ELR for use in enhancing geriatric APRN education and (b) to evaluate the educational utility of identified ELRs based on established criteria. A multilevel search strategy was used. Two independent team members reviewed identified ELR against established criteria to ensure utility. Only resources meeting all criteria were retained. Resources were found for each of the competency areas and included formats such as podcasts, Web casts, case studies, and teaching videos. In many cases, resources were identified using supplemental strategies and not through traditional search or search of existing geriatric repositories. Resources identified have been useful to advanced practice educators in improving lecture and seminar content in a particular topic area and providing students and preceptors with additional self-learning resources. Addressing sustainability within geriatric APRN education is critical for sharing of best practices among educators and for sustainability of teaching and related resources. © 2014.

  15. USE OF ELECTRONIC EDUCATIONAL RESOURCES WHEN TRAINING IN WORK WITH SPREADSHEETS

    Directory of Open Access Journals (Sweden)

    Х А Гербеков

    2017-12-01

    Full Text Available Today the tools for maintaining training courses based on opportunities of information and communication technologies are developed. Practically in all directions of preparation and on all subject matters electronic textbook and self-instruction manuals are created. Nevertheless the industry of computer educational and methodical materials actively develops and gets more and more areas of development and introduction. In this regard more and more urgent is a problem of development of the electronic educational resources adequate to modern educational requirements. Creation and the organization of training courses with use of electronic educational resources in particular on the basis of Internet technologies remains a difficult methodical task.In article the questions connected with development of electronic educational resources for use when studying the substantial line “Information technologies” of a school course of informatics in particular for studying of spreadsheets are considered. Also the analysis of maintenance of a school course and the unified state examination from the point of view of representation of task in him corresponding to the substantial line of studying “Information technologies” on mastering technology of information processing in spreadsheets and the methods of visualization given by means of charts and schedules is carried out.

  16. From Millennium ERM to Proquest 360 Resource Manager: Implementing a new Electronic Resources Management System ERMS in an International Graduate Research University in Saudi Arabia

    KAUST Repository

    Ramli, Rindra M.

    2017-01-01

    An overview of the Recommendation Study and the subsequent Implementation of a new Electronic Resources Management system ERMS in an international graduate research university in the Kingdom of Saudi Arabia. It covers the timeline, deliverables

  17. Availability, Level of Use and Constraints to Use of Electronic Resources by Law Lecturers in Public Universities in Nigeria

    Science.gov (United States)

    Amusa, Oyintola Isiaka; Atinmo, Morayo

    2016-01-01

    (Purpose) This study surveyed the level of availability, use and constraints to use of electronic resources among law lecturers in Nigeria. (Methodology) Five hundred and fifty-two law lecturers were surveyed and four hundred and forty-two responded. (Results) Data analysis revealed that the level of availability of electronic resources for the…

  18. Prognostic impact of RITA expression in patients with anal squamous cell carcinoma treated with chemoradiotherapy.

    Science.gov (United States)

    Rödel, Franz; Steinhäuser, Kerstin; Kreis, Nina-Naomi; Friemel, Alexandra; Martin, Daniel; Wieland, Ulrike; Rave-Fränk, Margret; Balermpas, Panagiotis; Fokas, Emmanouil; Louwen, Frank; Rödel, Claus; Yuan, Juping

    2018-02-01

    RBP-J interacting and tubulin-associated protein (RITA) has been identified as a negative regulator of the Notch signalling pathway and its deregulation is involved in the pathogenesis of several tumour entities. RITA's impact on the response of anal squamous cell carcinoma (SCC) to anticancer treatment, however, remains elusive. In our retrospective study immunohistochemical evaluation of RITA was performed on 140 pre-treatment specimens and was correlated with clinical and histopathologic characteristics and clinical endpoints cumulative incidence of local control (LC), distant recurrence (DC), disease-free survival (DFS) and overall survival (OS). We observed significant inverse correlations between RITA expression and tumour grading, the levels of HPV-16 virus DNA load, CD8 (+) tumour infiltrating lymphocytes and programmed death protein (PD-1) immunostaining. In univariate analyses, elevated levels of RITA expression were predictive for decreased local control (p = 0.001), decreased distant control (p = 0.040), decreased disease free survival (p = 0.001) and overall survival (p RITA expression remained significant for decreased local control (p = 0.009), disease free survival (p = 0.032) and overall survival (p = 0.012). These data indicate that elevated levels of pretreatment RITA expression are correlated with unfavourable clinical outcome in anal carcinoma treated with concomitant chemoradiotherapy. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. GUIDELINES FOR EVALUATION OF PSYCHOLOGICAL AND PEDAGOGICAL QUALITY CHARACTERISTICS OF ELECTRONIC EDUCATIONAL RESOURCES

    Directory of Open Access Journals (Sweden)

    Galina P. Lavrentieva

    2014-05-01

    Full Text Available The article highlights the causes of insufficient effective use of electronic learning resources and sets out the guidelines on ways to solve the aforementioned problems. The set of didactic, methodical, psychological, pedagogical, design and ergonomic quality requirements is considered for evaluation, selection and application of information and communication technologies in the educational process. The most appropriate mechanisms for the ICT introduction into the learning process are disclosed as it should meet the specific learning needs of the student and the objectives of the educational process. The guidance for psycho-educational assessment of quality of electronic educational resources is provided. It is argued that the effectiveness of the ICT use is to be improved by means of quality evaluation mechanisms involved into the educational process.

  20. [RITA combined with temozolomide inhibits the proliferation of human glioblastoma U87 cells].

    Science.gov (United States)

    He, Xiao-Yan; Feng, Xiao-Li; Song, Xin-Pei; Zeng, Huan-Chao; Cao, Zhong-Xu; Xiao, Wei-Wei; Zhang, Bao; Wu, Qing-Hua

    2016-10-20

    To observe the effect of RITA, a small molecule that targets p53, combined with temozolomide (TMZ) on proliferation, colony formation and apoptosis of human glioblastoma U87 cells and explore the underlying mechanism. Cultured U87 cells were treated with RITA (1, 5, 10, 20 µmol/L), TMZ, or RITA+TMZ (half dose) for 24, 48 or 72 h. MTS assay were used to detect the cell proliferation, and the cell proliferation rate and inhibitory rate were calculated. The effect of combined treatments was evaluated by the q value. The expressions of p53, p21 and other apoptosis-associated genes were detected by qRT-PCR and Western blotting; cell apoptosis was assayed using flow cytometry with Annexin V/PI double staining; colony formation of the cells was detected with crystal violet staining. MTS assay showed that RITA at the 4 doses more potently inhibited U87 cell viability than TMZ at 72 h (P=0.000) with inhibitory rates of 25.94%-41.38% and 3.84%-8.20%, respectively. RITA combined with TMZ caused a more significant inhibition of U87 cells (29.21%-52.11%) than RITA (PRITA+TMZ for 48 h resulted in q values exceeding 1.2 and showed an obvious synergistic effect of the drugs. Both RITA and TMZ, especially the latter, significantly increased the expressions of p53, p21, puma, and other apoptosis-associated genes to accelerate apoptosis and inhibit the growth and colony formation of U87 cells, and the effect was more obvious with a combined treatment. RITA inhibits the growth of human glioblastoma cells and enhance their sensitivity to TMZ by up-regulating p53 expression, and when combined, RITA and TMZ show a synergistic effect to cause a stronger cell inhibition.

  1. Model of e-learning with electronic educational resources of new generation

    OpenAIRE

    A. V. Loban; D. A. Lovtsov

    2017-01-01

    Purpose of the article: improving of scientific and methodical base of the theory of the е-learning of variability. Methods used: conceptual and logical modeling of the е-learning of variability process with electronic educational resource of new generation and system analysis of the interconnection of the studied subject area, methods, didactics approaches and information and communication technologies means. Results: the formalization complex model of the е-learning of variability with elec...

  2. Land Area Change and Fractional Water Maps in the Chenier Plain, Louisiana, following Hurricane Rita (2005)

    Science.gov (United States)

    Palaseanu-Lovejoy, Monica; Kranenburg, Christine J.; Brock, John C.

    2010-01-01

    In this study, we estimated the changes in land and water coverage of a 1,961-square-kilometer (km2) area in Louisiana's Chenier Plain. The study area is roughly centered on the Sabine National Wildlife Refuge, which was impacted by Hurricane Rita on September 24, 2005. The objective of this study is twofold: (1) to provide pre- and post-Hurricane Rita moderate-resolution (30-meter (m)) fractional water maps based upon multiple source images, and (2) to quantify land and water coverage changes due to Hurricane Rita.

  3. Positional stabilization of communications satellites - The RITA ion propulsion system is ready for commercial use

    Science.gov (United States)

    The radiofrequency ion thruster assembly (RITA) intended for service aboard the new Artemis communications satellite will operate for three hours twice a day, in order to furnish orbital position adjustments that keep antennas accurately pointed toward the earth. These engines are, despite such frequent and sustained use, projected to eject no more than 30 kG of Xe over the course of a decade. RITA operation is also extremely reliable and, due to its very low propellant consumption, is the basis of a long satellite service life. RITA will be among the 15 experiments that are to be performed by ESA's Eureca research satellite.

  4. A systematic review of portable electronic technology for health education in resource-limited settings.

    Science.gov (United States)

    McHenry, Megan S; Fischer, Lydia J; Chun, Yeona; Vreeman, Rachel C

    2017-08-01

    The objective of this study is to conduct a systematic review of the literature of how portable electronic technologies with offline functionality are perceived and used to provide health education in resource-limited settings. Three reviewers evaluated articles and performed a bibliography search to identify studies describing health education delivered by portable electronic device with offline functionality in low- or middle-income countries. Data extracted included: study population; study design and type of analysis; type of technology used; method of use; setting of technology use; impact on caregivers, patients, or overall health outcomes; and reported limitations. Searches yielded 5514 unique titles. Out of 75 critically reviewed full-text articles, 10 met inclusion criteria. Study locations included Botswana, Peru, Kenya, Thailand, Nigeria, India, Ghana, and Tanzania. Topics addressed included: development of healthcare worker training modules, clinical decision support tools, patient education tools, perceptions and usability of portable electronic technology, and comparisons of technologies and/or mobile applications. Studies primarily looked at the assessment of developed educational modules on trainee health knowledge, perceptions and usability of technology, and comparisons of technologies. Overall, studies reported positive results for portable electronic device-based health education, frequently reporting increased provider/patient knowledge, improved patient outcomes in both quality of care and management, increased provider comfort level with technology, and an environment characterized by increased levels of technology-based, informal learning situations. Negative assessments included high investment costs, lack of technical support, and fear of device theft. While the research is limited, portable electronic educational resources present promising avenues to increase access to effective health education in resource-limited settings, contingent

  5. Promoting mental health recovery after hurricanes Katrina and Rita: what can be done at what cost.

    Science.gov (United States)

    Schoenbaum, Michael; Butler, Brittany; Kataoka, Sheryl; Norquist, Grayson; Springgate, Benjamin; Sullivan, Greer; Duan, Naihua; Kessler, Ronald C; Wells, Kenneth

    2009-08-01

    Concerns about mental health recovery persist after the 2005 Gulf storms. We propose a recovery model and estimate costs and outcomes. To estimate the costs and outcomes of enhanced mental health response to large-scale disasters using the 2005 Gulf storms as a case study. Decision analysis using state-transition Markov models for 6-month periods from 7 to 30 months after disasters. Simulated movements between health states were based on probabilities drawn from the clinical literature and expert input. A total of 117 counties/parishes across Louisiana, Mississippi, Alabama, and Texas that the Federal Emergency Management Agency designated as eligible for individual relief following hurricanes Katrina and Rita. Hypothetical cohort, based on the size and characteristics of the population affected by the Gulf storms. Intervention Enhanced mental health care consisting of evidence-based screening, assessment, treatment, and care coordination. Morbidity in 6-month episodes of mild/moderate or severe mental health problems through 30 months after the disasters; units of service (eg, office visits, prescriptions, hospital nights); intervention costs; and use of human resources. Full implementation would cost $1133 per capita, or more than $12.5 billion for the affected population, and yield 94.8% to 96.1% recovered by 30 months, but exceed available provider capacity. Partial implementation would lower costs and recovery proportionately. Evidence-based mental health response is feasible, but requires targeted resources, increased provider capacity, and advanced planning.

  6. A Green Prison: Santa Rita Jail Creeps Towards Zero Net Energy (ZNE)

    Energy Technology Data Exchange (ETDEWEB)

    Marnay, Chris; DeForest, Nicholas; Stadler, Michael; Donadee, Jon; Dierckxsens, Carlos; Mendes, Goncalo; Lai, Judy; Cardoso, Goncalo Ferreira

    2011-03-18

    A large project is underway at Alameda County's twenty-year old 45 ha 4,000-inmate Santa Rita Jail, about 70 km east of San Francisco. Often described as a green prison, it has a considerable installed base of distributed energy resources including a seven-year old 1.2 MW PV array, a four-year old 1 MW fuel cell with heat recovery, and efficiency investments. A current US$14 M expansion will add approximately 2 MW of NaS batteries, and undetermined wind capacity and a concentrating solar thermal system. This ongoing effort by a progressive local government with considerable Federal and State support provides some excellent lessons for the struggle to lower building carbon footprint. The Distributed Energy Resources Customer Adoption Model (DER-CAM) finds true optimal combinations of equipment and operating schedules for microgrids that minimize energy bills and/or carbon emissions without 2 of 12 significant searching or rules-of-thumb prioritization, such as"efficiency first then on-site generation." The results often recommend complex systems, and sensitivities show how policy changes will affect choices. This paper reports an analysis of the historic performance of the PV system and fuel cell, describes the complex optimization applied to the battery scheduling, and shows how results will affect the jail's operational costs, energy consumption, and carbon footprint. DER-CAM is used to assess the existing and proposed DER equipment in its ability to reduce tariff charges.

  7. Model of e-learning with electronic educational resources of new generation

    Directory of Open Access Journals (Sweden)

    A. V. Loban

    2017-01-01

    Full Text Available Purpose of the article: improving of scientific and methodical base of the theory of the е-learning of variability. Methods used: conceptual and logical modeling of the е-learning of variability process with electronic educational resource of new generation and system analysis of the interconnection of the studied subject area, methods, didactics approaches and information and communication technologies means. Results: the formalization complex model of the е-learning of variability with electronic educational resource of new generation is developed, conditionally decomposed into three basic components: the formalization model of the course in the form of the thesaurusclassifier (“Author of e-resource”, the model of learning as management (“Coordination. Consultation. Control”, the learning model with the thesaurus-classifier (“Student”. Model “Author of e-resource” allows the student to achieve completeness, high degree of didactic elaboration and structuring of the studied material in triples of variants: modules of education information, practical task and control tasks; the result of the student’s (author’s of e-resource activity is the thesaurus-classifier. Model of learning as management is based on the principle of personal orientation of learning in computer environment and determines the logic of interaction between the lecturer and the student when determining the triple of variants individually for each student; organization of a dialogue between the lecturer and the student for consulting purposes; personal control of the student’s success (report generation and iterative search for the concept of the class assignment in the thesaurus-classifier before acquiring the required level of training. Model “Student” makes it possible to concretize the learning tasks in relation to the personality of the student and to the training level achieved; the assumption of the lecturer about the level of training of a

  8. Reflection on Lessons Learned: An Analysis of the Adverse Outcomes Observed During the Hurricane Rita Evacuation.

    Science.gov (United States)

    Baker, Karen

    2018-02-01

    In September 2005, nearly 3.7 million people evacuated the Texas coastline in advance of Hurricane Rita's landfall, making the event the largest emergency evacuation in US history. The Rita evacuation underscored the importance of planning for domestic mass-evacuation events, as the evacuation itself led to over 100 of the at least 119 deaths attributed to the storm. In the days preceding Rita's landfall, several cascading, interrelated circumstances precipitated such adverse outcomes. This article explores the series of events leading up to the evacuation's poor outcomes, the response following Rita to amend evacuation plans, and how Texas successfully implemented these changes during later storms to achieve better outcomes. (Disaster Med Public Health Preparedness. 2018;12:115-120).

  9. Review of material recovery from used electric and electronic equipment-alternative options for resource conservation.

    Science.gov (United States)

    Friege, Henning

    2012-09-01

    For waste from electric and electronic equipment, the WEEE Directive stipulates the separate collection of electric and electronic waste. As to new electric and electronic devices, the Restriction of Hazardous Substances (RoHS) Directive bans the use of certain chemicals dangerous for man and environment. From the implementation of the WEEE directive, many unsolved problems have been documented: poor collection success, emission of dangerous substances during collection and recycling, irretrievable loss of valuable metals among others. As to RoHS, data from the literature show a satisfying success. The problems identified in the process can be reduced to some basic dilemmas at the borders between waste management, product policy and chemical safety. The objectives of the WEEE Directive and the specific targets for use and recycling of appliances are not consistent. There is no focus on scarce resources. Extended producer responsibility is not sufficient to guarantee sustainable waste management. Waste management reaches its limits due to problems of implementation but also due to physical laws. A holistic approach is necessary looking at all branch points and sinks in the stream of used products and waste from electric and electronic equipment. This may be done with respect to the general rules for sustainable management of material streams covering the three dimensions of sustainable policy. The relationships between the players in the field of electric and electronic devices have to be taken into account. Most of the problems identified in the implementation process will not be solved by the current amendment of the WEEE Directive.

  10. [Use of internet and electronic resources among Spanish intensivist physicians. First national survey].

    Science.gov (United States)

    Gómez-Tello, V; Latour-Pérez, J; Añón Elizalde, J M; Palencia-Herrejón, E; Díaz-Alersi, R; De Lucas-García, N

    2006-01-01

    Estimate knowledge and use habits of different electronic resources in a sample of Spanish intensivists: Internet, E-mail, distribution lists, and use of portable electronic devices. Self-applied questionnaire. A 50-question questionnaire was distributed among Spanish intensivists through the hospital marketing delegates of a pharmaceutical company and of electronic forums. A total of 682 questionnaires were analyzed (participation: 74%). Ninety six percent of those surveyed used Internet individually: 67% admitted training gap. Internet was the second source of clinical consultations most used (61%), slightly behind consultation to colleagues (65%). The pages consulted most were bibliographic databases (65%) and electronic professional journals (63%), with limited use of Evidence Based Medicine pages (19%). Ninety percent of those surveyed used e-mail regularly in the practice of their profession, although 25% admitted that were not aware of its possibilities. The use of E-mail decreased significantly with increase in age. A total of 62% of the intensivists used distribution lists. Of the rest, 42% were not aware of its existence and 32% admitted they had insufficient training to handle them. Twenty percent of those surveyed had portable electronic devices and 64% considered it useful, basically due to its rapid consultation at bedside. Female gender was a negative predictive factor of its use (OR 0.35; 95% CI 0.2-0.63; p=0.0002). A large majority of the Spanish intensivists use Internet and E-mail. E-mail lists and use of portable devices are still underused resources. There are important gaps in training and infrequent use of essential pages. There are specific groups that require directed educational policies.

  11. Mold exposure and health effects following hurricanes Katrina and Rita.

    Science.gov (United States)

    Barbeau, Deborah N; Grimsley, L Faye; White, LuAnn E; El-Dahr, Jane M; Lichtveld, Maureen

    2010-01-01

    The extensive flooding in the aftermath of Hurricanes Katrina and Rita created conditions ideal for indoor mold growth, raising concerns about the possible adverse health effects associated with indoor mold exposure. Studies evaluating the levels of indoor and outdoor molds in the months following the hurricanes found high levels of mold growth. Homes with greater flood damage, especially those with >3 feet of indoor flooding, demonstrated higher levels of mold growth compared with homes with little or no flooding. Water intrusion due to roof damage was also associated with mold growth. However, no increase in the occurrence of adverse health outcomes has been observed in published reports to date. This article considers reasons why studies of mold exposure after the hurricane do not show a greater health impact.

  12. Transformative experiences for Hurricanes Katrina and Rita disaster volunteers.

    Science.gov (United States)

    Clukey, Lory

    2010-07-01

    The massive destruction caused by Hurricanes Katrina and Rita in 2005 provided an opportunity for many volunteers to be involved with disaster relief work. Exposure to devastation and personal trauma can have long-lasting and sometimes detrimental effects on people providing help. This qualitative study explored the experience of volunteer relief workers who provided disaster relief services after the hurricanes. Three major themes emerged: emotional reactions that included feelings of shock, fatigue, anger and grief as well as sleep disturbances; frustration with leadership; and life-changing personal transformation. Stress reactions were noted but appeared to be mitigated by feelings of compassion for the victims and personal satisfaction in being able to provide assistance. Suggestions are provided for further research.

  13. Stratigraphy of the Charqueadas Carboniferous basin, Santa Rita, RS, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Mendes Piccoli, A.E.; Holz, M.; Munaro, P.

    1985-01-01

    Sedimentological analyses of about 80 drill cores from the Charqueadas - Santa Rita Coal Field, west of Porto Alegre, Rio Grande do Sul State, were made. The Itarare Group is characterized by pelites of lacustrine origin and conglomerates and sandstones of alluvial fans, mainly in the north western region. A shallow lacustrine and paludal system characterize the Rio Bonito Formation, comprising coal seams and associated pelitic sediments, as well as some paraconglomerates and sandstone layers. The contact between these units is established by the colour of the pelites, differences in sedimentary textures, structures and palynological data. A marine transgression caused the sediments of the Rio Bonito Formation to be covered by coastal sandstones and pelites of the Palermo Formation, of tidal flat origin. Today, the coal layers and sediments have been eroded southward and slope gently to the north of the area.

  14. Katrina and Rita were lit up with lightning

    Science.gov (United States)

    Shao, X.-M.; Harlin, J.; Stock, M.; Stanley, M.; Regan, A.; Wiens, K.; Hamlin, T.; Pongratz, M.; Suszcynsky, D.; Light, T.

    Hurricanes generally produce very little lightning activity compared to other noncyclonic storms, and lightning is especially sparse in the eye wall and inner regions within tens of kilometers surrounding the eye [Molinari et al., 1994, 1999]. (The eye wall is the wall of clouds that encircles the eye of the hurricane.) Lightning can sometimes be detected in the outer, spiral rainbands, but the lightning occurrence rate varies significantly from hurricane to hurricane as well as within an individual hurricane's lifetime.Hurricanes Katrina and Rita hit the U.S. Gulf coasts of Louisiana, Mississippi, and Texas, and their distinctions were not just limited to their tremendous intensity and damage caused. They also differed from typical hurricanes in their lightning production rate.

  15. RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.

    Science.gov (United States)

    Wacker, Stephan Armin; Alvarado, Cristobal; von Wichert, Götz; Knippschild, Uwe; Wiedenmann, Jörg; Clauss, Karen; Nienhaus, Gerd Ulrich; Hameister, Horst; Baumann, Bernd; Borggrefe, Tilman; Knöchel, Walter; Oswald, Franz

    2011-01-05

    The evolutionarily conserved Notch signal transduction pathway regulates fundamental cellular processes during embryonic development and in the adult. Ligand binding induces presenilin-dependent cleavage of the receptor and a subsequent nuclear translocation of the Notch intracellular domain (NICD). In the nucleus, NICD binds to the recombination signal sequence-binding protein J (RBP-J)/CBF-1 transcription factor to induce expression of Notch target genes. Here, we report the identification and functional characterization of RBP-J interacting and tubulin associated (RITA) (C12ORF52) as a novel RBP-J/CBF-1-interacting protein. RITA is a highly conserved 36 kDa protein that, most interestingly, binds to tubulin in the cytoplasm and shuttles rapidly between cytoplasm and nucleus. This shuttling RITA exports RBP-J/CBF-1 from the nucleus. Functionally, we show that RITA can reverse a Notch-induced loss of primary neurogenesis in Xenopus laevis. Furthermore, RITA is able to downregulate Notch-mediated transcription. Thus, we propose that RITA acts as a negative modulator of the Notch signalling pathway, controlling the level of nuclear RBP-J/CBF-1, where its amounts are limiting.

  16. IGF-1R/MDM2 relationship confers enhanced sensitivity to RITA in Ewing sarcoma cells.

    Science.gov (United States)

    Di Conza, Giusy; Buttarelli, Marianna; Monti, Olimpia; Pellegrino, Marsha; Mancini, Francesca; Pontecorvi, Alfredo; Scotlandi, Katia; Moretti, Fabiola

    2012-06-01

    Ewing sarcoma is one of the most frequent bone cancers in adolescence. Although multidisciplinary therapy has improved the survival rate for localized tumors, a critical step is the development of new drugs to improve the long-term outcome of recurrent and metastatic disease and to reduce side effects of conventional therapy. Here, we show that the small molecule reactivation of p53 and induction of tumor cell apoptosis (RITA, NSC652287) is highly effective in reducing growth and tumorigenic potential of Ewing sarcoma cell lines. These effects occur both in the presence of wt-p53 as well as of mutant or truncated forms of p53, or in its absence, suggesting the presence of additional targets in this tumor histotype. Further experiments provided evidence that RITA modulates an important oncogenic mark of these cell lines, insulin-like growth factor receptor 1 (IGF-1R). Particularly, RITA causes downregulation of IGF-1R protein levels. MDM2 degradative activity is involved in this phenomenon. Indeed, inhibition of MDM2 function by genetic or pharmacologic approaches reduces RITA sensitivity of Ewing sarcoma cell lines. Overall, these data suggest that in the cell context of Ewing sarcoma, RITA may adopt additional mechanism of action besides targeting p53, expanding its field of application. Noteworthy, these results envisage the promising utilization of RITA or its derivative as a potential treatment for Ewing sarcomas. ©2012 AACR

  17. Rescue of the apoptotic-inducing function of mutant p53 by small molecule RITA.

    Science.gov (United States)

    Zhao, Carolyn Y; Grinkevich, Vera V; Nikulenkov, Fedor; Bao, Wenjie; Selivanova, Galina

    2010-05-01

    Expression of mutant p53 correlates with poor prognosis in many tumors, therefore strategies aimed at reactivation of mutant p53 are likely to provide important benefits for treatment of tumors that are resistant to chemotherapy and radiotherapy. We have previously identified and characterized a small molecule RITA which binds p53 and induces a conformational change which prevents the binding of p53 to several inhibitors, including its own destructor MDM2. In this way, RITA rescues the tumor suppression function of wild type p53. Here, we demonstrate that RITA suppressed the growth and induced apoptosis in human tumor cell lines of a diverse origin carrying mutant p53 proteins. RITA restored transcriptional transactivation and transrepression function of several hot spot p53 mutants. The ability of RITA to rescue the activity of different p53 mutants suggests its generic mechanism of action. Thus, RITA is a promising lead for the development of anti-cancer drugs that reactivate the tumor suppressor function of p53 in cancer cells irrespective whether they express mutant or wild type p53.

  18. A new perspective on autism: Rita Leal School

    Directory of Open Access Journals (Sweden)

    Rodrigues T. F.

    2016-12-01

    Full Text Available Guided by the principle that scientific knowledge should serve to transform reality and create suitable conditions of life for all, the Portuguese Association for Relational-Historical Psychology (APPRH founded a school named RITA LEAL (RLS, with a therapeutic purpose based on new perspectives for treating autism — perspectives quite different from instrumental and behavioral learning programs. The Rita Leal School (Leal, 1975/2004, 1997, 2005, 2010 is rooted in the theory that mental development is based on a mutually contingent emotional relationship, while it underwrites Vygotsky’s concept of the Zone of Proximal Development (ZPD and Mediation (1930/2004, 1934/2009. Learning to read is a complex process which individuals with Autism Spectrum Disorder (ASD master slowly and with difficulty. We analyzed the process of learning to read of two ASD children accompanied by peers without special educational needs, aiming to pinpoint distinct aspects of their progress. We used the Observer Software Program to collect and analyze observations of their performance, which were understood as data to be classified according to previously specified codes. We believed we could demonstrate that, especially in the case of ASD children, learning is dependent on contingent responses and adequate levels of mediation. The technical team at the RLS has continuous clinical supervision. That is because we believe this supervision is what permits the team to undergo a process of de-centering, becoming more empathic and accessible to the autists. This makes the team’s intervention more efficient, because it becomes more aware of each autist’s individual characteristics, and therefore more available to respond to the autist’s needs.

  19. Impact of hurricanes katrina and rita on the anesthesiology workforce.

    Science.gov (United States)

    Hutson, Larry R; Vega, Jorge; Schubert, Armin

    2011-01-01

    Hurricanes Katrina and Rita impacted a large portion of the medical community in Louisiana. We attempt to determine their impact on the anesthesiology workforce in Louisiana. In May 2006, a survey was mailed to 368 Louisiana anesthesiologists, collecting demographic data, retirement plans, impact of Hurricanes Katrina and Rita, position vacancies, practice conditions, and the general state of healthcare in their area. All 3 anesthesiology residency programs in the state were contacted regarding their recent graduates. The 2010 RAND survey of the anesthesiology workforce was reviewed with respect to findings relevant to the state and region. One hundred seventy surveys were returned, yielding a 46.2% response rate. Among the respondents, 13.9% intended to retire within 5 years and another 24% in 5 to 10 years. Since 2005, 63.9% had seen an increase in their daily caseload, 46.9% saw an increase in work hours, and 36.8% stated that their practices were trying to hire new anesthesiologists and were having difficulty filling these positions. Since 2005, the number of anesthesiology residents in Louisiana had declined by almost 50%, and the number of graduates remaining to practice in Louisiana had decreased by 43% from 7 to 4 annually. Our 2006 survey provided qualitative evidence for a shortage of anesthesiologists in the state of Louisiana after the natural disasters in 2005 that was likely to worsen as residency output plummeted, fewer residents stayed in the state, and projected retirement increased. The regional data from the RAND survey a year later confirmed the impressions from our survey, with an estimate of an anesthesiologist shortage as high as 39% of the workforce. State membership surveys may serve as accurate barometers in the wake of major environmental upheavals affecting regional anesthesiology workforce conditions.

  20. The Synthesis of the Hierarchical Structure of Information Resources for Management of Electronic Commerce Entities

    Directory of Open Access Journals (Sweden)

    Krutova Anzhelika S.

    2017-06-01

    Full Text Available The aim of the article is to develop the theoretical bases for the classification and coding of economic information and the scientific justification of the content of information resources of an electronic commerce enterprise. The essence of information resources for management of electronic business entities is investigated. It is proved that the organization of accounting in e-commerce systems is advisable to be built on the basis of two circuits: accounting for financial flows and accounting associated with transformation of business factors in products and services as a result of production activities. There presented a sequence of accounting organization that allows to combine the both circuits in a single information system, which provides a possibility for the integrated replenishment and distributed simultaneous use of the e-commerce system by all groups of users. It is proved that the guarantee of efficient activity of the information management system of electronic commerce entities is a proper systematization of the aggregate of information resources on economic facts and operations of an enterprise in accordance with the management tasks by building the hierarchy of accounting nomenclatures. It is suggested to understand nomenclature as an objective, primary information aggregate concerning a certain fact of the economic activity of an enterprise, which is characterized by minimum requisites, is entered into the database of the information system and is to be reflected in the accounting system. It is proposed to build a database of e-commerce systems as a part of directories (constants, personnel, goods / products, suppliers, buyers and the hierarchy of accounting nomenclatures. The package of documents regulating the organization of accounting at an enterprise should include: the provision on the accounting services, the order on the accounting policy, the job descriptions, the schedules of information exchange, the report card and

  1. ELECTRONIC EDUCATIONAL RESOURCES FOR ONLINE SUPPORT OF MODERN CHEMISTRY CLASSES IN SPECIALIZED SCHOOL

    Directory of Open Access Journals (Sweden)

    Maria D. Tukalo

    2013-09-01

    Full Text Available This article contains material of some modern electronic educational resources that can be used via the Internet to support the modern chemistry classes in specialized school. It was drawn attention to the educational chemical experiments as means of knowledge; simulated key motivational characteristics to enhance students interest for learning subjects, their cognitive and practical activity in the formation of self-reliance and self-creative; commented forecasts for creating of conditions to enhance the creative potential of students in a modern learning environment.

  2. THE MODEL OF LINGUISTIC TEACHERS’ COMPETENCY DEVELOPMENT ON DESIGNING MULTIMEDIA ELECTRONIC EDUCATIONAL RESOURCES IN THE MOODLE SYSTEM

    Directory of Open Access Journals (Sweden)

    Anton M. Avramchuk

    2017-10-01

    Full Text Available The article is devoted to the problem of developing the competency of teachers of language disciplines on designing multimedia electronic educational resources in the Moodle system. The concept of "the competence of teachers of language disciplines on designing multimedia electronic educational resources in the Moodle system" is justified and defined. Identified and characterized the components by which the levels of the competency development of teachers of language disciplines on designing multimedia electronic educational resources in the Moodle system should be assessed. Developed a model for the development of the competency of teachers of language disciplines on designing multimedia electronic educational resources in the Moodle system, which is based on the main scientific approaches, used in adult education, and consists of five blocks: target, informative, technological, diagnostic and effective.

  3. A preliminary categorization of end-of-life electrical and electronic equipment as secondary metal resources

    International Nuclear Information System (INIS)

    Oguchi, Masahiro; Murakami, Shinsuke; Sakanakura, Hirofumi; Kida, Akiko; Kameya, Takashi

    2011-01-01

    Highlights: → End-of-life electrical and electronic equipment (EEE) as secondary metal resources. → The content and the total amount of metals in specific equipment are both important. → We categorized 21 EEE types from contents and total amounts of various metals. → Important equipment types as secondary resources were listed for each metal kind. → Collectability and possible collection systems of various EEE types were discussed. - Abstract: End-of-life electrical and electronic equipment (EEE) has recently received attention as a secondary source of metals. This study examined characteristics of end-of-life EEE as secondary metal resources to consider efficient collection and metal recovery systems according to the specific metals and types of EEE. We constructed an analogy between natural resource development and metal recovery from end-of-life EEE and found that metal content and total annual amount of metal contained in each type of end-of-life EEE should be considered in secondary resource development, as well as the collectability of the end-of-life products. We then categorized 21 EEE types into five groups and discussed their potential as secondary metal resources. Refrigerators, washing machines, air conditioners, and CRT TVs were evaluated as the most important sources of common metals, and personal computers, mobile phones, and video games were evaluated as the most important sources of precious metals. Several types of small digital equipment were also identified as important sources of precious metals; however, mid-size information and communication technology (ICT) equipment (e.g., printers and fax machines) and audio/video equipment were shown to be more important as a source of a variety of less common metals. The physical collectability of each type of EEE was roughly characterized by unit size and number of end-of-life products generated annually. Current collection systems in Japan were examined and potentially appropriate collection

  4. Open-Source Electronic Health Record Systems for Low-Resource Settings: Systematic Review.

    Science.gov (United States)

    Syzdykova, Assel; Malta, André; Zolfo, Maria; Diro, Ermias; Oliveira, José Luis

    2017-11-13

    Despite the great impact of information and communication technologies on clinical practice and on the quality of health services, this trend has been almost exclusive to developed countries, whereas countries with poor resources suffer from many economic and social issues that have hindered the real benefits of electronic health (eHealth) tools. As a component of eHealth systems, electronic health records (EHRs) play a fundamental role in patient management and effective medical care services. Thus, the adoption of EHRs in regions with a lack of infrastructure, untrained staff, and ill-equipped health care providers is an important task. However, the main barrier to adopting EHR software in low- and middle-income countries is the cost of its purchase and maintenance, which highlights the open-source approach as a good solution for these underserved areas. The aim of this study was to conduct a systematic review of open-source EHR systems based on the requirements and limitations of low-resource settings. First, we reviewed existing literature on the comparison of available open-source solutions. In close collaboration with the University of Gondar Hospital, Ethiopia, we identified common limitations in poor resource environments and also the main requirements that EHRs should support. Then, we extensively evaluated the current open-source EHR solutions, discussing their strengths and weaknesses, and their appropriateness to fulfill a predefined set of features relevant for low-resource settings. The evaluation methodology allowed assessment of several key aspects of available solutions that are as follows: (1) integrated applications, (2) configurable reports, (3) custom reports, (4) custom forms, (5) interoperability, (6) coding systems, (7) authentication methods, (8) patient portal, (9) access control model, (10) cryptographic features, (11) flexible data model, (12) offline support, (13) native client, (14) Web client,(15) other clients, (16) code

  5. RITA plus 3-MA overcomes chemoresistance of head and neck cancer cells via dual inhibition of autophagy and antioxidant systems.

    Science.gov (United States)

    Shin, Daiha; Kim, Eun Hye; Lee, Jaewang; Roh, Jong-Lyel

    2017-10-01

    Reactivation of p53 and induction of tumor cell apoptosis (RITA) is a small molecule that blocks p53-MDM2 interaction, thereby reactivating p53 in tumors. RITA can induce exclusive apoptosis in cancer cells independently of the p53 pathway; however, the resistance of cancer cells remains a major drawback. Here, we found a novel resistance mechanism of RITA treatment and an effective combined treatment to overcome RITA resistance in head and neck cancer (HNC) cells. The effects of RITA and 3-methyladenine (3-MA) were tested in different HNC cell lines, including cisplatin-resistant and acquired RITA-resistant HNC cells. The effects of each drug alone and in combination were assessed by measuring cell viability, apoptosis, cell cycle, glutathione, reactive oxygen species, protein expression, genetic inhibition of p62 and Nrf2, and a mouse xenograft model of cisplatin-resistant HNC. RITA induced apoptosis of HNC cells at different levels without significantly inhibiting normal cell viability. Following RITA treatment, RITA-resistant HNC cells exhibited a sustained expression of other autophagy-related proteins, overexpressed p62, and displayed activation of the Keap1-Nrf2 antioxidant pathway. The autophagy inhibitor 3-MA sensitized resistant HNC cells to RITA treatment via the dual inhibition of molecules related to the autophagy and antioxidant systems. Silencing of the p62 gene augmented the combined effects. The effective antitumor activity of RITA plus 3-MA was also confirmed in vivo in mouse xenograft models transplanted with resistant HNC cells, showing increased oxidative stress and DNA damage. The results indicate that RITA plus 3-MA can help overcome RITA resistance in HNC cells. This study revealed a novel RITA resistant mechanism associated with the sustained induction of autophagy, p62 overexpression, and Keap1-Nrf2 antioxidant system activation. The combined treatment of RITA with the autophagy inhibitor 3-methyladenine overcomes RITA resistance via dual

  6. Nephrologic Impact of Hurricanes Katrina and Rita in Areas Not Directly Affected.

    Science.gov (United States)

    Dossabhoy, Neville R; Qadri, Mashood; Beal, Lauren M

    2015-01-01

    Hurricanes Katrina and Rita resulted in enormous loss of life and disrupted the delivery of health care in areas affected by them. In causing mass movements of patients, natural disasters can overwhelm the resources of nephrology communities in areas not suffering direct damage. The following largely personal account evaluates the impact these hurricanes had upon the nephrology community, patients and health care providers alike, in areas not directly affected by the storms. Mass evacuation of hundreds of dialysis patients to surrounding areas overwhelmed the capacity of local hemodialysis centers. Non-availability of medical records in patients arriving without a supply of their routine medications led to confusion and sub-optimal treatment of conditions such as hypertension and congestive heart failure. Availability of cadaveric organs for transplantation was reduced in the surrounding areas, as the usual lines of communication and transportation were severed for several weeks. All of these issues led to prolong waiting times for patients on the transplant list. The hurricanes severely disrupted usual supply lines of medications to hospitals; certain rare conditions may be seen in higher numbers as a result of the shortages induced. We present the interesting surge in cases of acute kidney injury secondary to use of intravenous immune globulin.

  7. THE MODEL OF LINGUISTIC TEACHERS’ COMPETENCY DEVELOPMENT ON DESIGNING MULTIMEDIA ELECTRONIC EDUCATIONAL RESOURCES IN THE MOODLE SYSTEM

    OpenAIRE

    Anton M. Avramchuk

    2017-01-01

    The article is devoted to the problem of developing the competency of teachers of language disciplines on designing multimedia electronic educational resources in the Moodle system. The concept of "the competence of teachers of language disciplines on designing multimedia electronic educational resources in the Moodle system" is justified and defined. Identified and characterized the components by which the levels of the competency development of teachers of language disciplines on designing ...

  8. Determining the level of awareness of the physicians in using the variety of electronic information resources and the effecting factors.

    Science.gov (United States)

    Papi, Ahmad; Ghazavi, Roghayeh; Moradi, Salimeh

    2015-01-01

    Understanding of the medical society's from the types of information resources for quick and easy access to information is an imperative task in medical researches and management of the treatment. The present study was aimed to determine the level of awareness of the physicians in using various electronic information resources and the factors affecting it. This study was a descriptive survey. The data collection tool was a researcher-made questionnaire. The study population included all the physicians and specialty physicians of the teaching hospitals affiliated to Isfahan University of Medical Sciences and numbered 350. The sample size based on Morgan's formula was set at 180. The content validity of the tool was confirmed by the library and information professionals and the reliability was 95%. Descriptive statistics were used including the SPSS software version 19. On reviewing the need of the physicians to obtain the information on several occasions, the need for information in conducting the researches was reported by the maximum number of physicians (91.9%) and the usage of information resources, especially the electronic resources, formed 65.4% as the highest rate with regard to meeting the information needs of the physicians. Among the electronic information databases, the maximum awareness was related to Medline with 86.5%. Among the various electronic information resources, the highest awareness (43.3%) was related to the E-journals. The highest usage (36%) was also from the same source. The studied physicians considered the most effective deterrent in the use of electronic information resources as being too busy and lack of time. Despite the importance of electronic information resources for the physician's community, there was no comprehensive knowledge of these resources. This can lead to less usage of these resources. Therefore, careful planning is necessary in the hospital libraries in order to introduce the facilities and full capabilities of the

  9. Success criteria for electronic medical record implementations in low-resource settings: a systematic review.

    Science.gov (United States)

    Fritz, Fleur; Tilahun, Binyam; Dugas, Martin

    2015-03-01

    Electronic medical record (EMR) systems have the potential of supporting clinical work by providing the right information at the right time to the right people and thus make efficient use of resources. This is especially important in low-resource settings where reliable data are also needed to support public health and local supporting organizations. In this systematic literature review, our objectives are to identify and collect literature about success criteria of EMR implementations in low-resource settings and to summarize them into recommendations. Our search strategy relied on PubMed queries and manual bibliography reviews. Studies were included if EMR implementations in low-resource settings were described. The extracted success criteria and measurements were summarized into 7 categories: ethical, financial, functionality, organizational, political, technical, and training. We collected 381 success criteria with 229 measurements from 47 articles out of 223 articles. Most papers were evaluations or lessons learned from African countries, published from 1999 to 2013. Almost half of the EMR systems served a specific disease area like human immunodeficiency virus (HIV). The majority of criteria that were reported dealt with the functionality, followed by organizational issues, and technical infrastructures. Sufficient training and skilled personnel were mentioned in roughly 10%. Political, ethical, and financial considerations did not play a predominant role. More evaluations based on reliable frameworks are needed. Highly reliable data handling methods, human resources and effective project management, as well as technical architecture and infrastructure are all key factors for successful EMR implementation. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  10. Ritacestus gen. n. (Cestoda: Proteocephalidea) and redescription of R. ritaii comb. n., a parasite of Rita rita (Siluriformes) in India.

    Science.gov (United States)

    de Chambrier, Alain; Scholz, Tomás; Ash, Anirban; Kar, Pradip Kumar

    2011-11-01

    A new genus, Ritacestus, is proposed to accommodate Ritacestus ritaii (Verma, 1926) comb. n. (syn. Proteocephalus ritaii), a parasite of the catfish Rita rita (Hamilton) in India. The new genus, which is placed in the Gangesiinae, is characterized by (i) a small, subspherical scolex formed by four large lobes separated from one another by longitudinal grooves, with a large, widely oval to pyriform rostellum-like apical organ, larger than suckers and possessing an apical hemispherical depression; (ii) paramuscular and cortical position of some vitelline follicles (most follicles are situated medullary); (iii) ventral and dorsal bands of vitelline follicles usually uninterrupted ventral to terminal genitalia and reaching to the posterior margin of proglottides; (iv) the vagina always anterior to the cirrus-sac; (v) a large size of the body (length up to 51 cm); and (vi) development of the uterus of type 2. In its morphology, especially shape of the scolex and apical organ, and paramuscular and cortical position of some vitelline follicles, Ritacestus resembles Postgangesia Akhmerov, 1969, but differs in the presence of a genital atrium (both genital pores of Postgangesia are separate), the anterior position of the vagina (almost always posterior in the latter genus), position of vitelline follicles in cross sections (dorsal and ventral bands in Ritacestus versus only a lateral band in the latter genus), and dorsal excretory canals indistinguishable in mature and gravid proglottides of R. ritaii (well developed in Postgangesia spp.). The type and only species of the genus, R. ritaii, is redescribed on the basis of new material from the type host from the Ganges River basin in India and its neotype is designated.

  11. Impact of Knowledge Resources Linked to an Electronic Health Record on Frequency of Unnecessary Tests and Treatments

    Science.gov (United States)

    Goodman, Kenneth; Grad, Roland; Pluye, Pierre; Nowacki, Amy; Hickner, John

    2012-01-01

    Introduction: Electronic knowledge resources have the potential to rapidly provide answers to clinicians' questions. We sought to determine clinicians' reasons for searching these resources, the rate of finding relevant information, and the perceived clinical impact of the information they retrieved. Methods: We asked general internists, family…

  12. Resource conservation approached with an appropriate collection and upgrade-remanufacturing for used electronic products.

    Science.gov (United States)

    Zlamparet, Gabriel I; Tan, Quanyin; Stevels, A B; Li, Jinhui

    2018-03-01

    This comparative research represents an example for a better conservation of resources by reducing the amount of waste (kg) and providing it more value under the umbrella of remanufacturing. The three discussed cases will expose three issues already addressed separately in the literature. The generation of waste electrical and electronic equipment (WEEE) interacts with the environmental depletion. In this article, we gave the examples of addressed issues under the concept of remanufacturing. Online collection opportunity eliminating classical collection, a business to business (B2B) implementation for remanufactured servers and medical devices. The material reuse (recycling), component sustainability, reuse (part harvesting), product reuse (after repair/remanufacturing) indicates the recovery potential using remanufacturing tool for a better conservation of resources adding more value to the products. Our findings can provide an overview of new system organization for the general collection, market potential and the technological advantages using remanufacturing instead of recycling of WEEE or used electrical and electronic equipment. Copyright © 2017. Published by Elsevier Ltd.

  13. Electronic theses and dissertations: a review of this valuable resource for nurse scholars worldwide.

    Science.gov (United States)

    Goodfellow, L M

    2009-06-01

    A worldwide repository of electronic theses and dissertations (ETDs) could provide worldwide access to the most up-to-date research generated by masters and doctoral students. Until that international repository is established, it is possible to access some of these valuable knowledge resources. ETDs provide a technologically advanced medium with endless multimedia capabilities that far exceed the print and bound copies of theses and dissertations housed traditionally in individual university libraries. CURRENT USE: A growing trend exists for universities worldwide to require graduate students to submit theses or dissertations as electronic documents. However, nurse scholars underutilize ETDs, as evidenced by perusing bibliographic citation lists in many of the research journals. ETDs can be searched for and retrieved through several digital resources such as the Networked Digital Library of Theses and Dissertations (http://www.ndltd.org), ProQuest Dissertations and Theses (http://www.umi.com), the Australasian Digital Theses Program (http://adt.caul.edu.au/) and through individual university web sites and online catalogues. An international repository of ETDs benefits the community of nurse scholars in many ways. The ability to access recent graduate students' research electronically from anywhere in the world is advantageous. For scholars residing in developing countries, access to these ETDs may prove to be even more valuable. In some cases, ETDs are not available for worldwide access and can only be accessed through the university library from which the student graduated. Public access to university library ETD collections is not always permitted. Nurse scholars from both developing and developed countries could benefit from ETDs.

  14. From Millennium ERM to Proquest 360 Resource Manager: Implementing a new Electronic Resources Management System ERMS in an International Graduate Research University in Saudi Arabia

    KAUST Repository

    Ramli, Rindra M.

    2017-05-17

    An overview of the Recommendation Study and the subsequent Implementation of a new Electronic Resources Management system ERMS in an international graduate research university in the Kingdom of Saudi Arabia. It covers the timeline, deliverables and challenges as well as lessons learnt by the Project Team.

  15. Electronic tracking of human resource skills and knowledge, just in time training, manageable due diligence

    Energy Technology Data Exchange (ETDEWEB)

    Kolodziej, M.A. [Quick Test International Inc., (Canada). Canadian Technology Human Resource Board; Baker, O. [KeySpan Energy Canada, Calgary, AB (Canada)

    2001-06-01

    KeySpan Energy Canada is in the process of obtaining recognition of various occupational profiles including pipeline operators, inspectors, and field and plant operators from various certifying organizations. The process of allowing individuals to obtain certification is recognized by Canadian Technology Human Resources Board as a step towards national standards for technologists and technicians. Proven competency is a must for workers in todays oil industry in response to increasingly stringent government safety regulations, environmental concerns and high public scrutiny. Quick Test international Inc. has developed a management tool in collaboration with end users at KeySpan Energy Canada. It is an electronic, Internet based competency tool for tracking personal competencies and maintaining continued competency. Response to the tool has been favourable. 2 refs., 4 figs.

  16. 44 CFR 206.209 - Arbitration for Public Assistance determinations related to Hurricanes Katrina and Rita (Major...

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Arbitration for Public Assistance determinations related to Hurricanes Katrina and Rita (Major disaster declarations DR-1603, DR... determinations related to Hurricanes Katrina and Rita (Major disaster declarations DR-1603, DR-1604, DR-1605, DR...

  17. Recognizing history in range ecology: 100 years of science and management on the Santa Rita Experimental Range

    Science.gov (United States)

    Nathan F. Sayre

    2003-01-01

    At the centennial of the Santa Rita Experimental Range, historical analysis is called for on two levels. First, as a major site in the history of range ecology, the Santa Rita illuminates past successes and failures in science and management and the ways in which larger social, economic, and political factors have shaped scientific research. Second, with the turn away...

  18. Availability, Use and Constraints to Use of Electronic Information Resources by Postgraduates Students at the University of Ibadan

    Directory of Open Access Journals (Sweden)

    Dare Samuel Adeleke

    2017-12-01

    Full Text Available Availability, awareness and use of electronic resources provide access to authoritative, reliable, accurate and timely access to information. The use of electronic information resources (EIRs can enable innovation in teaching and increase timeliness in research of postgraduate students which will eventual result into encouragement of the expected research-led enquiry in this digital age. The study adopted a descriptive survey design. Samples of 300 of postgraduate students within seven out 13 Faculties were randomly selected. Data were collected using questionnaire designed to elicit response from respondents and data were analyzed using descriptive statistics methods percentages, mean, and standard deviation. Results indicated that internet was ranked most available and used in the university. Low level of usage of electronic resources, in particular, full texts data bases is linked to a number of constraints: Interrupted power supply was ranked highest among other factors as speed and capacity of computers, retrieval of records with high recall and low precision, retrieving records relevant to information need, lack of knowledge of search techniques to retrieve information effectively, non possession of requisite IT skills and problems accessing the internet. The study recommended that usage of electronic resources be made compulsory, intensifying awareness campaigns concerning the availability, training on use of electronic resources and the problem of power outage be addressed.

  19. Using mobile electronic devices to deliver educational resources in developing countries.

    Science.gov (United States)

    Mazal, Jonathan Robert; Ludwig, Rebecca

    2015-01-01

    Developing countries have far fewer trained radiography professionals than developed countries, which exacerbates the limited access to imaging services. The lack of trained radiographers reflects, in part, limited availability of radiographer-specific educational resources. Historically, organizations that provided such resources in the developing world faced challenges related to the limited stock of current materials as well as expenses associated with shipping and delivery. Four mobile electronic devices (MEDs) were loaded with educational content (e-books, PDFs, and digital applications) spanning major radiography topics. The MEDs were distributed to 4 imaging departments in Ghana, India, Nepal, and Nigeria based on evidence of need for radiography-specific resources, as revealed by survey responses. A cost comparison of postal delivery vs digital delivery of educational content was performed. The effectiveness of delivering additional content via Wi-Fi transmission also was evaluated. Feedback was solicited on users' experience with the MEDs as a delivery tool for educational content. An initial average per e-book expense of $30.05, which included the cost of the device, was calculated for the MED delivery method compared with $15.56 for postal delivery of printed materials. The cost of the MED delivery method was reduced to an average of $10.05 for subsequent e-book deliveries. Additional content was successfully delivered via Wi-Fi transmission to all recipients during the 3-month follow-up period. Overall user feedback on the experience was positive, and ideas for enhancing the MED-based method were identified. Using MEDs to deliver radiography-specific educational content appears to be more cost effective than postal delivery of printed materials on a long-term basis. MEDs are more efficient for providing updates to educational materials. Customization of content to department needs, and using projector devices could enhance the usefulness of MEDs for

  20. Monitoring Inland Storm Surge and Flooding from Hurricane Rita

    Science.gov (United States)

    McGee, Benton D.; Tollett, Roland W.; Mason, Jr., Robert R.

    2006-01-01

    Pressure transducers (sensors) and high-water marks were used to document the inland water levels related to storm surge generated by Hurricane Rita in southwestern Louisiana and southeastern Texas. On September 22-23, 2005, an experimental monitoring network of sensors was deployed at 33 sites over an area of about 4,000 square miles to record the timing, extent, and magnitude of inland hurricane storm surge and coastal flooding. Sensors were programmed to record date and time, temperature, and barometric or water pressure. Water pressure was corrected for changes in barometric pressure and salinity. Elevation surveys using global-positioning systems and differential levels were used to relate all storm-surge water-level data, reference marks, benchmarks, sensor measuring points, and high-water marks to the North American Vertical Datum of 1988 (NAVD 88). The resulting data indicated that storm-surge water levels over 14 feet above NAVD 88 occurred at three locations, and rates of water-level rise greater than 5 feet per hour occurred at three locations near the Louisiana coast.

  1. Entrevista a María Rita Otero

    Directory of Open Access Journals (Sweden)

    Olga Lucia Castiblanco Abril

    2016-09-01

    Full Text Available OC: Dra. María Rita, bienvenida a esta sección de la revista en donde siempre queremos que nuestros lectores conozcan personas de la vida académica en el campo de la investigación en Enseñeanza de las Ciencias. En primer lugar, nos gustaría que nos contara algo sobre su lugar actual como docente e invstigadora. MRO: Muchas gracias por la invitación. Quisiera contarles que hasta hace dos años fui profesora de secundaria durante 33 años. Actualmente soy profesora titular de la Universidad del Centro de la Provincia de Buenos Aires y soy investigadora principal del Consejo Nacional de Ciencia y tecnología de la República Argentina (Conicet. OC: ¿Cuál es su área de investigación? MRO: Estoy adscrita en el área de psicología y educación. Dentro de esta área trabajo en didáctica de las ciencias. Dirijo un equipo dentro de la universidad que se dedica a esto y a formar profesores de matemáticas, física e informática y también dirijo el doctorado.

  2. The electronic encapsulation of knowledge in hydraulics, hydrology and water resources

    Science.gov (United States)

    Abbott, Michael B.

    The rapidly developing practice of encapsulating knowledge in electronic media is shown to lead necessarily to the restructuring of the knowledge itself. The consequences of this for hydraulics, hydrology and more general water-resources management are investigated in particular relation to current process-simulation, real-time control and advice-serving systems. The generic properties of the electronic knowledge encapsulator are described, and attention is drawn to the manner in which knowledge 'goes into hiding' through encapsulation. This property is traced in the simple situations of pure mathesis and in the more complex situations of taxinomia using one example each from hydraulics and hydrology. The consequences for systems architectures are explained, pointing to the need for multi-agent architectures for ecological modelling and for more general hydroinformatics systems also. The relevance of these developments is indicated by reference to ongoing projects in which they are currently being realised. In conclusion, some more general epistemological aspects are considered within the same context. As this contribution is so much concerned with the processes of signification and communication, it has been partly shaped by the theory of semiotics, as popularised by Eco ( A Theory of Semiotics, Indiana University, Bloomington, 1977).

  3. Plastics disassembly versus bulk recycling: engineering design for end-of-life electronics resource recovery.

    Science.gov (United States)

    Rios, Pedro; Stuart, Julie Ann; Grant, Ed

    2003-12-01

    Annual plastic flows through the business and consumer electronics manufacturing supply chain include nearly 3 billion lb of high-value engineering plastics derived from petroleum. The recovery of resource value from this stream presents critical challenges in areas of materials identification and recycling process design that demand new green engineering technologies applied together with life cycle assessment and ecological supply chain analysis to create viable plastics-to-plastics supply cycles. The sustainable recovery of potentially high-value engineering plastics streams requires that recyclers either avoid mixing plastic parts or purify later by separating smaller plastic pieces created in volume reduction (shredding) steps. Identification and separation constitute significant barriers in the plastics-to-plastics recycling value proposition. In the present work, we develop a model that accepts randomly arriving electronic products to study scenarios by which a recycler might identify and separate high-value engineering plastics as well as metals. Using discrete eventsimulation,we compare current mixed plastics recovery with spectrochemical plastic resin identification and subsequent sorting. Our results show that limited disassembly with whole-part identification can produce substantial yields in separated streams of recovered engineering thermoplastics. We find that disassembly with identification does not constitute a bottleneck, but rather, with relatively few workers, can be configured to pull the process and thus decrease maximum staging space requirements.

  4. Status of the RITA - experiment on EURECA. [Radio Frequency Ion Thrustor Assembly

    Energy Technology Data Exchange (ETDEWEB)

    Bassner, H.; Berg, H.P.; Birner, W.; Bartoli, C.; Trippi, A.

    1987-01-01

    The radiofrequency ion thruster assembly (RITA) is currently built as a flight experiment which shall be flown on the European retrievable carrier (Eureca I). This test flight shall verify the operational use of this electric propulsion system in space by demonstration of operation, lifetime and reliability. For this purpose the RITA experiment has been adapted to meet the specific constraints imposed by the Eureca I spacecraft and by the Space Shuttle as the launcher; xenon gas will be used as the propellant and the experiment will be operated automatically by means of a dedicated on-board microcomputer system. According to the delay in launches by the Space Shuttle the launch date has been postponed from March 1988 to 1991/92. Therefore the total Eureca program has been extended, which also influenced the RITA time schedule.

  5. SAGES: a suite of freely-available software tools for electronic disease surveillance in resource-limited settings.

    Directory of Open Access Journals (Sweden)

    Sheri L Lewis

    Full Text Available Public health surveillance is undergoing a revolution driven by advances in the field of information technology. Many countries have experienced vast improvements in the collection, ingestion, analysis, visualization, and dissemination of public health data. Resource-limited countries have lagged behind due to challenges in information technology infrastructure, public health resources, and the costs of proprietary software. The Suite for Automated Global Electronic bioSurveillance (SAGES is a collection of modular, flexible, freely-available software tools for electronic disease surveillance in resource-limited settings. One or more SAGES tools may be used in concert with existing surveillance applications or the SAGES tools may be used en masse for an end-to-end biosurveillance capability. This flexibility allows for the development of an inexpensive, customized, and sustainable disease surveillance system. The ability to rapidly assess anomalous disease activity may lead to more efficient use of limited resources and better compliance with World Health Organization International Health Regulations.

  6. Electronic Human Resources Management (e-HRM Adoption Studies: Past and Future Research

    Directory of Open Access Journals (Sweden)

    Winarto Winarto

    2018-05-01

    Full Text Available Electronic human resource management (e-HRM systems become more widely used by profit and non-profit organization. However, the field currently lacks sound theoretical frameworks that can be useful in addressing a key issue concerning the implementation of e-HRM systems, in particular to obtain a better understanding of the factors influencing the adoption of e-HRM systems. The objective of this paper is to provide a foundation towards the development of a theoretical framework for the implementation of e-HRM systems and develop a conceptual model that would reflect the nature of e-HRM systems’ adoption through systematic literature review. Adopting Crossan and Apaydin’s procedure of systematic review, this paper investigated 21 empirical papers of electronics human resources management, then categorized them into 4 characteristics which influence the adoption; System and technology characteristics; Organizational characteristics; User/individual characteristics, and Environmental and contextual characteristics. Finally, the e-HRM adoption research framework is drawn and based on the framework; avenues for future research are discussed.   Bahasa Indonesia Abstrak: Manajemen sumber daya manusia elektronik (selanjutnya disebut dengan e-HRM semakin banyak digunakan oleh organisasi profit dan nonprofit. Namun, bidang dan topik ini belum memiliki kerangka teori yang mapan, yang dapat digunakan untuk menganalisis isu-isu terkait penerapan e-HRM, terutama mengenai faktor-faktor yang mempengaruhi adopsi sistem e-HRM. Tujuan penelitian ini adalah untuk memberikan landasan bagi pengembangan kerangka teoritis untuk implementasi sistem e-HRM dan mengembangkan model konseptual yang akan menggambarkan adopsi sistem e-HRM melalui tinjauan literatur sistematis. Mengadopsi prosedur dan metode Crossan dan Apaydin untuk melakukan telaah literatur secara sistematis, paper ini menyelidiki 21 publikasi empiris manajemen sumber daya manusia elektronik dari 2

  7. The p53-reactivating small-molecule RITA enhances cisplatin-induced cytotoxicity and apoptosis in head and neck cancer.

    Science.gov (United States)

    Roh, Jong-Lyel; Ko, Jung Ho; Moon, Soo Jin; Ryu, Chang Hwan; Choi, Jun Young; Koch, Wayne M

    2012-12-01

    We evaluated whether the restoration of p53 function by the p53-reactivating small molecule RITA (reactivation of p53 and induction of tumor cell apoptosis enhances cisplatin-induced cytotoxicity and apoptosis in head-and-neck cancer (HNC). RITA induced prominent accumulation and reactivation of p53 in a wild-type TP53-bearing HNC cell line. RITA showed maximal growth suppression in tumor cells showing MDM2-dependent p53 degradation. RITA promoted apoptosis in association with upregulation of p21, BAX, and cleaved caspase-3; notably, the apoptotic response was blocked by pifithrin-α, demonstrating its p53 dependence. With increasing concentrations, RITA strongly induced apoptosis rather than G2-phase arrest. In combination therapy, RITA enhanced cisplatin-induced growth inhibition and apoptosis of HNC cells invitro and in vivo. Our data suggest that the restoration of p53 tumor-suppressive function by RITA enhances the cytotoxicity and apoptosis of cisplatin, an action that may offer an attractive strategy for treating HNC. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  8. The Recent Infection Testing Algorithm (RITA) in clinical practice: a survey of HIV clinicians in England and Northern Ireland.

    Science.gov (United States)

    Garrett, Nj; Lattimore, S; Gilbart, Vl; Aghaizu, A; Mensah, G; Tosswill, J; Murphy, G; Delpech, V

    2012-08-01

    In order to estimate HIV incidence among high-risk groups, in January 2009 the Health Protection Agency introduced the Recent Infection Testing Algorithm (RITA) in England and Northern Ireland (E&NI), currently the only regions to inform patients of RITA results. This survey of HIV specialists aimed to investigate the role of RITA in patient management and explore clinicians' views on its role in clinical practice and during partner notification. An online questionnaire was distributed to HIV specialists via the British HIV Association membership email list in February 2011. Forty-two HIV specialists from 32 HIV centres responded to the survey among 90 centres enrolled in the programme (response rate 36%). Testing for recent infection was considered standard of care by 83% of respondents, 80% felt confident in interpreting results and 92% discussed results with patients, particularly in the context of a possible HIV seroconversion illness (96%) or when deciding when to start antiretroviral therapy (70%). A third (36%) of specialists were initially concerned that RITA results may cause additional anxiety among patients; however, no adverse events were reported. The majority (90%) felt that results could assist with contact tracing by prioritizing patients with likely recent infection. However, only a few centres have currently incorporated RITA into their HIV partner notification protocols. RITA has been introduced into clinical practice with no reported patient adverse events. Access to results at centre level should be improved. National guidance regarding use of RITA as a tool for contact tracing is required. © 2012 British HIV Association.

  9. RITA enhances chemosensivity of pre-B ALL cells to doxorubicin by inducing p53-dependent apoptosis.

    Science.gov (United States)

    Kazemi, Ahmad; Safa, Majid; Shahbazi, Atefeh

    2011-07-01

    The use of low-molecular-weight, non-peptidic molecules that disrupt the interaction between the p53 tumor suppressor and its negative regulator MDM2 has provided a promising alternative for the treatment of different types of cancer. Here, we used small-molecule reactivation of p53 and induction of tumor cell apoptosis (RITA) to sensitize leukemic NALM-6 cells to doxorubicin by upregulating p53 protein. RITA alone effectively inhibited NALM-6 cells viability in dose-dependent manner as measured by 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide assay and induced apoptosis as evaluated by flow cytometry, whereas RITA in combination with doxorubicin enhanced NALM-6 cells to doxorubicin-sensitivity and promoted doxorubicin induced apoptosis. Levels of p53 protein and its proapoptotic target genes, quantified by western blot and real-time PCR respectively, showed that expression of p53 was significantly increased after RITA treatment. Using p53 inhibitors PFT-alpha and PFT-mu it was shown that p53-mediated apoptosis induced by RITA can be regulated by both p53-transcription-dependent and -independent pathways. Moreover, RITA-induced apoptosis was accompanied by the activation of caspase-3 and PARP cleavage. Therefore, exploiting synergistic effects between RITA and chemotherapeutics might be an effective clinical strategy for leukemia chemotherapy.

  10. Impact of Electronic Resources and Usage in Academic Libraries in Ghana: Evidence from Koforidua Polytechnic & All Nations University College, Ghana

    Science.gov (United States)

    Akussah, Maxwell; Asante, Edward; Adu-Sarkodee, Rosemary

    2015-01-01

    The study investigates the relationship between impact of electronic resources and its usage in academic libraries in Ghana: evidence from Koforidua Polytechnic & All Nations University College, Ghana. The study was a quantitative approach using questionnaire to gather data and information. A valid response rate of 58.5% was assumed. SPSS…

  11. Utilization of Electronic Information Resources by Undergraduate Students of University of Ibadan: A Case Study of Social Sciences and Education

    Science.gov (United States)

    Owolabi, Sola; Idowu, Oluwafemi A.; Okocha, Foluke; Ogundare, Atinuke Omotayo

    2016-01-01

    The study evaluated utilization of electronic information resources by undergraduates in the Faculties of Education and the Social Sciences in University of Ibadan. The study adopted a descriptive survey design with a study population of 1872 undergraduates in the Faculties of Education and the Social Sciences in University of Ibadan, from which a…

  12. Systematic review of electronic surveillance of infectious diseases with emphasis on antimicrobial resistance surveillance in resource-limited settings.

    Science.gov (United States)

    Rattanaumpawan, Pinyo; Boonyasiri, Adhiratha; Vong, Sirenda; Thamlikitkul, Visanu

    2018-02-01

    Electronic surveillance of infectious diseases involves rapidly collecting, collating, and analyzing vast amounts of data from interrelated multiple databases. Although many developed countries have invested in electronic surveillance for infectious diseases, the system still presents a challenge for resource-limited health care settings. We conducted a systematic review by performing a comprehensive literature search on MEDLINE (January 2000-December 2015) to identify studies relevant to electronic surveillance of infectious diseases. Study characteristics and results were extracted and systematically reviewed by 3 infectious disease physicians. A total of 110 studies were included. Most surveillance systems were developed and implemented in high-income countries; less than one-quarter were conducted in low-or middle-income countries. Information technologies can be used to facilitate the process of obtaining laboratory, clinical, and pharmacologic data for the surveillance of infectious diseases, including antimicrobial resistance (AMR) infections. These novel systems require greater resources; however, we found that using electronic surveillance systems could result in shorter times to detect targeted infectious diseases and improvement of data collection. This study highlights a lack of resources in areas where an effective, rapid surveillance system is most needed. The availability of information technology for the electronic surveillance of infectious diseases, including AMR infections, will facilitate the prevention and containment of such emerging infectious diseases. Copyright © 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  13. Rangeland livestock production: Developing the concept of sustainability on the Santa Rita Experimental Range

    Science.gov (United States)

    George B. Ruyle

    2003-01-01

    The Santa Rita Experimental Range (SRER) was established in 1903 at the behest of concerned stockmen and researchers as the first facility in the United States set aside to study range livestock production. At the time, severe overgrazing of the public domain had seriously reduced carrying capacities of Southwestern rangelands. Researchers on the SRER developed and...

  14. Archive and laboratory embedded in the landscape: Future of the Santa Rita Experimental Range

    Science.gov (United States)

    Thomas E. Sheridan

    2003-01-01

    The Santa Rita Experimental Range (SRER) is both an archive of past ecological research and a laboratory for continuing research embedded in the southern Arizona landscape. The scientific questions being asked there have changed over the last 100 years, but SRER with its monitoring stations and its legacy of repeat photography still offers a unique opportunity to study...

  15. Sweet resin bush on the Santa Rita Experimental Range: An eradication effort

    Science.gov (United States)

    Larry D. Howery; Bruce D. Munda; Dan G. Robinett; Harry H. Buck

    2003-01-01

    Sweet resin bush (Euryops subcarnosus DC ssp. vulgaris B. Nord; or, Euryops multifidis (L. f.) DC.), a South African shrub introduced to Arizona in the 1930s, was discovered on the Santa Rita Experimental Range (SRER) in 1998. Due to the threat of spread of this invasive plant and its potential to cause adverse environmental and economic effects, and because it posed a...

  16. 75 FR 22770 - Gary E. Hall and Rita Hall; Notice of Availability of Environmental Assessment

    Science.gov (United States)

    2010-04-30

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13652-000-Montana] Gary E. Hall and Rita Hall; Notice of Availability of Environmental Assessment April 22, 2010. In accordance with the National Environmental Policy Act of 1969, as amended, and the Federal Energy Regulatory...

  17. "Making Lemonade from Lemons:" Early Childhood Teacher Educators' Programmatic Responses to Hurricanes Katrina and Rita

    Science.gov (United States)

    DiCarlo, Cynthia F.; Burts, Diane C.; Buchanan, Teresa K.; Aghayan, Carol; Benedict, Joan

    2007-01-01

    This article describes how early childhood teacher education faculty at one university responded in the aftermath of hurricanes Katrina and Rita and used the disaster to enhance their undergraduate and graduate programs. They explain how they modeled developmentally appropriate practices while responding to community needs. Four companion articles…

  18. Vascular plants and a brief history of the Kiowa and Rita Blanca National Grasslands

    Science.gov (United States)

    Donald L. Hazlett; Michael H. Schiebout; Paulette L. Ford

    2009-01-01

    Administered by the USDA Forest Service, the Kiowa and Rita Blanca National Grasslands occupy 230,000 acres of public land extending from northeastern New Mexico into the panhandles of Oklahoma and Texas. A mosaic of topographic features including canyons, plateaus, rolling grasslands and outcrops supports a diverse flora. Eight hundred twenty six (826) species of...

  19. Inelastic neutron scattering experiments with the monochromatic imaging mode of the RITA-II spectrometer

    DEFF Research Database (Denmark)

    Bahl, Christian Robert Haffenden; Lefmann, Kim; Abrahamsen, Asger Bech

    2006-01-01

    Recently a monochromatic multiple data taking mode has been demonstrated for diffraction experiments using a RITA type cold neutron spectrometer with a multi-bladed analyser and a position-sensitive detector. Here, we show how this mode can be used in combination with a flexible radial collimator...

  20. Missed by the Mass Media: The Houma, Pointe-au-Chien, and Hurricanes Katrina and Rita

    Science.gov (United States)

    Collins, Robert Keith

    2008-01-01

    This case study investigates the media discourse from Houma and Pointe-au-Chien tribal leaders in Louisiana on their experiences with Hurricanes Katrina and Rita. One section briefly engages the discourse as discernable from the reports found in Native American and non-Native American news media. Included is a brief yet close examination of these…

  1. Lightcurves for Shape Modeling: 852 Wladilena, 1089 Tama, and 1180 Rita

    Science.gov (United States)

    Polishook, David

    2012-10-01

    The folded lightcurves and synodic periods of 852 Wladilena, 1089 Tama, and 1180 Rita are reported. The data are used by Hanus et al. (2012) to derive the rotation axis and to construct a shape model by applying the inversion lightcurve technique.

  2. REMOTE SENSING DAMAGE ASSESSMENT OF CHEMICAL PLANTS AND REFINERIES FOLLOWING HURRICANES KATRINA AND RITA

    Science.gov (United States)

    The massive destruction brought by Hurricanes Katrina and Rita also impacted the many chemical plants and refineries in the region. The achievement of this rapid analysis capability highlights the advancement of this technology for air quality assessment and monitoring. Case st...

  3. Rita Lobato: a primeira médica formada no Brasil

    Directory of Open Access Journals (Sweden)

    Francisco Bruno Lobo

    2017-04-01

    Dentre elas foi escolhida a primeira mulher que se diplomou em medicina em uma Faculdade brasileira: A Dra. Rita Lobato de Freitas . No dia 9 de junho, aniversário de seu nascimento, o referido sêlo entrou em circulação.

  4. Geology of Santa Rita Coal Basin, Rio Grande do Sul, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Correa da Silva, Z.C.; Bortoluzzi, C.A.; Cazzulo-Klepzig, M.; Dias-Fabricio, M.E.; Guerra-Sommer, M.; Marques-Toigo, M.; Paim, P.S.G.; Piccoli, A.E.M.; Silva Filho, B.C.

    1984-04-01

    Data on the sedimentology, stratigraphy, palynology, coal petrography and geochemistry of the Santa Rita Coal Basin, Rio Grande do Sul, Brazil, are presented. The investigations were carried out on samples obtained from drill cores of the sedimentary rocks of Tubarao Supergroup, Lower Permian of Parana Basin. (25 refs.)

  5. The Impact of Hurricanes Katrina and Rita on Louisiana School Nurses

    Science.gov (United States)

    Broussard, Lisa; Myers, Rachel; Meaux, Julie

    2008-01-01

    In the fall of 2005, the coast of Louisiana was devastated by two hurricanes, Katrina and Rita. Not only did these natural disasters have detrimental effects for those directly in their path, the storms had an impact on the lives of everyone in Louisiana. The professional practice of many Louisiana school nurses was affected by several factors,…

  6. The Use of Electronic Resources by Academic Staff at the University of Ilorin, Nigeria

    Science.gov (United States)

    Tella, Adeyinka; Orim, Faith; Ibrahim, Dauda Morenikeji; Memudu, Suleiman Ajala

    2018-01-01

    The use of e-resources is now commonplace among academics in tertiary educational institutions the world over. Many academics including those in the universities are exploring the opportunities of e-resources to facilitate teaching and research. As the use of e-resources is increasing particularly among academics at the University of Ilorin,…

  7. Modeling antecedents of electronic medical record system implementation success in low-resource setting hospitals.

    Science.gov (United States)

    Tilahun, Binyam; Fritz, Fleur

    2015-08-01

    With the increasing implementation of Electronic Medical Record Systems (EMR) in developing countries, there is a growing need to identify antecedents of EMR success to measure and predict the level of adoption before costly implementation. However, less evidence is available about EMR success in the context of low-resource setting implementations. Therefore, this study aims to fill this gap by examining the constructs and relationships of the widely used DeLone and MacLean (D&M) information system success model to determine whether it can be applied to measure EMR success in those settings. A quantitative cross sectional study design using self-administered questionnaires was used to collect data from 384 health professionals working in five governmental hospitals in Ethiopia. The hospitals use a comprehensive EMR system since three years. Descriptive and structural equation modeling methods were applied to describe and validate the extent of relationship of constructs and mediating effects. The findings of the structural equation modeling shows that system quality has significant influence on EMR use (β = 0.32, P quality has significant influence on EMR use (β = 0.44, P service quality has strong significant influence on EMR use (β = 0.36, P effect of EMR use on user satisfaction was not significant. Both EMR use and user satisfaction have significant influence on perceived net-benefit (β = 0.31, P mediating factor in the relationship between service quality and EMR use (P effect on perceived net-benefit of health professionals. EMR implementers and managers in developing countries are in urgent need of implementation models to design proper implementation strategies. In this study, the constructs and relationships depicted in the updated D&M model were found to be applicable to assess the success of EMR in low resource settings. Additionally, computer literacy was found to be a mediating factor in EMR use and user satisfaction of

  8. Metal concentrations in schoolyard soils from New Orleans, Louisiana before and after Hurricanes Katrina and Rita.

    Science.gov (United States)

    Presley, Steven M; Abel, Michael T; Austin, Galen P; Rainwater, Thomas R; Brown, Ray W; McDaniel, Les N; Marsland, Eric J; Fornerette, Ashley M; Dillard, Melvin L; Rigdon, Richard W; Kendall, Ronald J; Cobb, George P

    2010-06-01

    The long-term environmental impact and potential human health hazards resulting from Hurricanes Katrina and Rita throughout much of the United States Gulf Coast, particularly in the New Orleans, Louisiana, USA area are still being assessed and realized after more than four years. Numerous government agencies and private entities have collected environmental samples from throughout New Orleans and found concentrations of contaminants exceeding human health screening values as established by the United States Environmental Protection Agency (USEPA) for air, soil, and water. To further assess risks of exposure to toxic concentrations of soil contaminants for citizens, particularly children, returning to live in New Orleans following the storms, soils collected from schoolyards prior to Hurricane Katrina and after Hurricane Rita were screened for 26 metals. Concentrations exceeding USEPA Regional Screening Levels (USEPA-RSL), total exposure, non-cancer endpoints, for residential soils for arsenic (As), iron (Fe), lead (Pb), and thallium (Tl) were detected in soil samples collected from schoolyards both prior to Hurricane Katrina and after Hurricane Rita. Approximately 43% (9/21) of schoolyard soils collected prior to Hurricane Katrina contained Pb concentrations greater than 400mgkg(-1), and samples from four schoolyards collected after Hurricane Rita contained detectable Pb concentrations, with two exceeding 1700mgkg(-1). Thallium concentrations exceeded USEPA-RSL in samples collected from five schoolyards after Hurricane Rita. Based upon these findings and the known increased susceptibility of children to the effects of Pb exposure, a more extensive assessment of the soils in schoolyards, public parks and other residential areas of New Orleans for metal contaminants is warranted. 2010 Elsevier Ltd. All rights reserved.

  9. Hurricane Rita Track Radar Image with Topographic Overlay

    Science.gov (United States)

    2005-01-01

    [figure removed for brevity, see original site] Animation About the animation: This simulated view of the potential effects of storm surge flooding on Galveston and portions of south Houston was generated with data from the Shuttle Radar Topography Mission. Although it is protected by a 17-foot sea wall against storm surges, flooding due to storm surges caused by major hurricanes remains a concern. The animation shows regions that, if unprotected, would be inundated with water. The animation depicts flooding in one-meter increments. About the image: The Gulf Coast from the Mississippi Delta through the Texas coast is shown in this satellite image from NASA's Moderate Resolution Imaging Spectroradiometer (MODIS) overlain with data from the Shuttle Radar Topography Mission (SRTM), and the predicted storm track for Hurricane Rita. The prediction from the National Weather Service was published Sept. 22 at 4 p.m. Central Time, and shows the expected track center in black with the lighter shaded area indicating the range of potential tracks the storm could take. Low-lying terrain along the coast has been highlighted using the SRTM elevation data, with areas within 15 feet of sea level shown in red, and within 30 feet in yellow. These areas are more at risk for flooding and the destructive effects of storm surge and high waves. Data used in this image were acquired by the Shuttle Radar Topography Mission aboard the Space Shuttle Endeavour, launched on Feb. 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect 3-D measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter (approximately 200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between NASA, the National Geospatial

  10. Use and Cost of Electronic Resources in Central Library of Ferdowsi University Based on E-metrics

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Davarpanah

    2012-07-01

    Full Text Available The purpose of this study was to investigate the usage of electronic journals in Ferdowsi University, Iran based on e-metrics. The paper also aimed to emphasize the analysis of cost-benefit and the correlation between the journal impact factors and the usage data. In this study experiences of Ferdowsi University library on licensing and usage of electronic resources was evaluated by providing a cost-benefit analysis based on the cost and usage statistics of electronic resources. Vendor-provided data were also compared with local usage data. The usage data were collected by tracking web-based access locally, and by collecting vender-provided usage data. The data sources were one-year of vendor-supplied e-resource usage data such as Ebsco, Elsevier, Proquest, Emerald, Oxford and Springer and local usage data collected from the Ferdowsi university web server. The study found that actual usage values differ for vendor-provided data and local usage data. Elsevier has got the highest usage degree in searches, sessions and downloads. Statistics also showed that a small number of journals satisfy significant amount of use while the majority of journals were used less frequent and some were never used at all. The users preferred the PDF rather than HTML format. The data in subject profile suggested that the provided e-resources were best suited to certain subjects. There was no correlation between IF and electronic journal use. Monitoring the usage of e-resources gained increasing importance for acquisition policy and budget decisions. The article provided information about local metrics for the six surveyed vendors/publishers, e.g. usage trends, requests per package, cost per use as related to the scientific specialty of the university.

  11. EAARL coastal topography and imagery–Western Louisiana, post-Hurricane Rita, 2005: First surface

    Science.gov (United States)

    Bonisteel-Cormier, Jamie M.; Wright, Wayne C.; Fredericks, Alexandra M.; Klipp, Emily S.; Nagle, Doug B.; Sallenger, Asbury H.; Brock, John C.

    2013-01-01

    These remotely sensed, geographically referenced color-infrared (CIR) imagery and elevation measurements of lidar-derived first-surface (FS) topography datasets were produced by the U.S. Geological Survey (USGS), St. Petersburg Coastal and Marine Science Center, St. Petersburg, Florida, and the National Aeronautics and Space Administration (NASA), Wallops Flight Facility, Virginia. This project provides highly detailed and accurate datasets of a portion of the Louisiana coastline beachface, acquired post-Hurricane Rita on September 27-28 and October 2, 2005. The datasets are made available for use as a management tool to research scientists and natural-resource managers. An innovative airborne lidar instrument originally developed at the National Aeronautics and Space Administration (NASA) Wallops Flight Facility, and known as the Experimental Advanced Airborne Research Lidar (EAARL), was used during data acquisition. The EAARL system is a raster-scanning, waveform-resolving, green-wavelength (532-nanometer) lidar designed to map near-shore bathymetry, topography, and vegetation structure simultaneously. The EAARL sensor suite includes the raster-scanning, water-penetrating full-waveform adaptive lidar, a down-looking red-green-blue (RGB) digital camera, a high-resolution multispectral color-infrared (CIR) camera, two precision dual-frequency kinematic carrier-phase GPS receivers, and an integrated miniature digital inertial measurement unit, which provide for sub-meter georeferencing of each laser sample. The nominal EAARL platform is a twin-engine Cessna 310 aircraft, but the instrument may be deployed on a range of light aircraft. A single pilot, a lidar operator, and a data analyst constitute the crew for most survey operations. This sensor has the potential to make significant contributions in measuring sub-aerial and submarine coastal topography within cross-environmental surveys. Elevation measurements were collected over the survey area using the EAARL

  12. Hurricane Rita Aerial Photography: High-Resolution Imagery of the Texas and Louisiana Gulf Coast After Landfall

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The imagery posted on this site is of the Texas and Louisiana Gulf Coast after Hurricane Rita made landfall. The regions photographed range from San Luis Pass, Texas...

  13. Use and User Perception of Electronic Information Resources: A Case Study of Siva Institute of Frontier Technology, India

    Directory of Open Access Journals (Sweden)

    Velmurugan Chandran

    2013-12-01

    Full Text Available The present study aims to explore the use and user perception of electronic resources in Siva Institute of Frontier Technology, India. A total number of 123 users were taken into account for the study through a questionnaire-based survey method. A well-structured questionnaire was designed and distributed to the selected 200 students and staff members. 123 copies of the questionnaires were returned dully filled in and the overall response rate was 61.50 percent. The questionnaire contained both open- and close-ended questions. The collected data were classified, analyzed, and tabulated by using simple statistical methods. This study covers the impact of electronic resources on students and faculty in their academic pursuit.

  14. Challenges in the implementation of an electronic surveillance system in a resource-limited setting: Alerta, in Peru

    Directory of Open Access Journals (Sweden)

    Soto Giselle

    2008-11-01

    Full Text Available Abstract Background Infectious disease surveillance is a primary public health function in resource-limited settings. In 2003, an electronic disease surveillance system (Alerta was established in the Peruvian Navy with support from the U.S. Naval Medical Research Center Detachment (NMRCD. Many challenges arose during the implementation process, and a variety of solutions were applied. The purpose of this paper is to identify and discuss these issues. Methods This is a retrospective description of the Alerta implementation. After a thoughtful evaluation according to the Centers for Disease Control and Prevention (CDC guidelines, the main challenges to implementation were identified and solutions were devised in the context of a resource-limited setting, Peru. Results After four years of operation, we have identified a number of challenges in implementing and operating this electronic disease surveillance system. These can be divided into the following categories: (1 issues with personnel and stakeholders; (2 issues with resources in a developing setting; (3 issues with processes involved in the collection of data and operation of the system; and (4 issues with organization at the central hub. Some of the challenges are unique to resource-limited settings, but many are applicable for any surveillance system. For each of these challenges, we developed feasible solutions that are discussed. Conclusion There are many challenges to overcome when implementing an electronic disease surveillance system, not only related to technology issues. A comprehensive approach is required for success, including: technical support, personnel management, effective training, and cultural sensitivity in order to assure the effective deployment of an electronic disease surveillance system.

  15. RESEARCH OF INFLUENCE OF QUALITY OF ELECTRONIC EDUCATIONAL RESOURCES ON QUALITY OF TRAINING WITH USE OF DISTANCE TECHNOLOGIES

    Directory of Open Access Journals (Sweden)

    H. M. Kravtsov

    2013-03-01

    Full Text Available Communication improving of educational processes requires today new approaches to the management arrangements and forming of educational policy in the field of distance learning, which is based on the use of modern information and communication technologies. An important step in this process is the continuous monitoring of the development and implementation of information technology and, in particular, the distance learning systems in higher educational establishments. The main objective of the monitoring is the impact assessment on the development of distance learning following the state educational standards, curricula, methodical and technical equipment and other factors; factors revelation that influence the implementation and outcomes of distance learning; results comparison of educational institution functioning and distance education systems in order to determine the most efficient ways of its development. The paper presents the analysis results of the dependence of the quality of educational services on the electronic educational resources. Trends in educational services development was studied by comparing the quality influence of electronic educational resources on the quality of educational services of higher pedagogical educational institutions of Ukraine as of 2009-2010 and 2012-2013. Generally, the analysis of the survey results allows evaluating quality of the modern education services as satisfactory and it can be said that almost 70% of the success of their future development depends on the quality of the used electronic educational resources and distance learning systems in particular.

  16. Tracking the Flow of Resources in Electronic Waste - The Case of End-of-Life Computer Hard Disk Drives.

    Science.gov (United States)

    Habib, Komal; Parajuly, Keshav; Wenzel, Henrik

    2015-10-20

    Recovery of resources, in particular, metals, from waste flows is widely seen as a prioritized option to reduce their potential supply constraints in the future. The current waste electrical and electronic equipment (WEEE) treatment system is more focused on bulk metals, where the recycling rate of specialty metals, such as rare earths, is negligible compared to their increasing use in modern products, such as electronics. This study investigates the challenges in recovering these resources in the existing WEEE treatment system. It is illustrated by following the material flows of resources in a conventional WEEE treatment plant in Denmark. Computer hard disk drives (HDDs) containing neodymium-iron-boron (NdFeB) magnets were selected as the case product for this experiment. The resulting output fractions were tracked until their final treatment in order to estimate the recovery potential of rare earth elements (REEs) and other resources contained in HDDs. The results further show that out of the 244 kg of HDDs treated, 212 kg comprising mainly of aluminum and steel can be finally recovered from the metallurgic process. The results further demonstrate the complete loss of REEs in the existing shredding-based WEEE treatment processes. Dismantling and separate processing of NdFeB magnets from their end-use products can be a more preferred option over shredding. However, it remains a technological and logistic challenge for the existing system.

  17. HELP (INFORMATION ELECTRONIC RESOURCE "CHRONICLE OF ONU: DATES, FACTS, EVENTS": HISTORY OF UNIVERSITY IN INFORMATION SPACE

    Directory of Open Access Journals (Sweden)

    А. М. Гавриленко

    2016-03-01

    Object of research is the help information resource "The chronicle of the Odessa national university of I. I. Mechnikov: dates, facts, events". The main objective of our article – to state the main methodological bases of creation of information resource. One of advantages of information resource is possibility of continuous updating and replenishment by new information. Main objective of creation of this information resource is systematization of material on stories of the Odessa national university of I. I. Mechnikov from the date of his basis to the present, ensuring interactive access to information on the main dates, the most significant events in life of university. The base of research are sources on the history of university, chronology of historical development, formation of infrastructure, cadres and scientific researches. In information resource the main stages of development, functioning and transformation of the Odessa University are analyzed, information on its divisions is collected. For creation of this information resource in Scientific library the method of work was developed, the main selection criteria of data are allocated. This information resource have practical value for all who is interested in history of university, historians, scientists-researchers of history of science and the city of Odessa.

  18. Print and Electronic Resources: Usage Statistics at Guru Gobind Singh Indraprastha University Library

    Science.gov (United States)

    Kapoor, Kanta

    2010-01-01

    Purpose: The purpose of this paper is to quantify the use of electronic journals in comparison with the print collections in the Guru Gobind Singh Indraprastha University Library. Design/methodology/approach: A detailed analysis was made of the use of lending services, the Xerox facility and usage of electronic journals such as Science Direct,…

  19. Understanding intention to use electronic information resources: A theoretical extension of the technology acceptance model (TAM).

    Science.gov (United States)

    Tao, Donghua

    2008-11-06

    This study extended the Technology Acceptance Model (TAM) by examining the roles of two aspects of e-resource characteristics, namely, information quality and system quality, in predicting public health students' intention to use e-resources for completing research paper assignments. Both focus groups and a questionnaire were used to collect data. Descriptive analysis, data screening, and Structural Equation Modeling (SEM) techniques were used for data analysis. The study found that perceived usefulness played a major role in determining students' intention to use e-resources. Perceived usefulness and perceived ease of use fully mediated the impact that information quality and system quality had on behavior intention. The research model enriches the existing technology acceptance literature by extending TAM. Representing two aspects of e-resource characteristics provides greater explanatory information for diagnosing problems of system design, development, and implementation.

  20. Formation of processes erosion associated with the use and occupation of soil in the Ribeira river basin, city of Santa Rita / PB | Formação de erosão de processos associada ao uso e ocupação do solo na bacia do rio Ribeira, cidade de Santa Rita / PB

    Directory of Open Access Journals (Sweden)

    Caio Lima dos Santos

    2016-06-01

    Full Text Available The way the man has appropriated natural resources, has been revealed as the source of many problems in the environment, which has been reflected directly in the depletion of natural resources and quality of life. The erosion and loss of soil are part of these degenerative processes of the natural landscape. The watershed of the river Ribeira, located in Santa Rita, Paraíba State, is a current example of such processes that are directly associated with forms of land use. Actions arising mainly from the extensive cultivation of cane sugar has been revealed through the development of geomorphological processes that mark the landscape through erosional features, such as small fillets, grooves, and gully, plus a large amount of alluvial fans that protrude over the lowlands often silted water bodies.

  1. Eye of the storm: analysis of shelter treatment records of evacuees to Acadiana from Hurricanes Katrina and Rita.

    Science.gov (United States)

    Caillouet, L Philip; Paul, P Joseph; Sabatier, Steven M; Caillouet, Kevin A

    2012-01-01

    specific evaluation and care, no population-based experimental hypothesis was framed nor was the effectiveness of any specific intervention researched at the time. This study reports experiential data collected without a particular preconceived hypothesis, because no specific outcome measures had been designed in advance. Data analysis revealed much about the origins and demographics of the evacuees, their hurricane-related risks and injuries, and the loss of continuity in their prior and ongoing healthcare. The authors believe that much can be learned from studying data collected in evacuee triage clinics, and that such insights may influence personal and official preparedness for future events. In the Katrina-Rita evacuations, only paper-based data collection mechanisms were used-and those with great inconsistency-and there was no predeployed mechanism for close-to-real-time collation of evacuee data. Deployment of simple electronic health record systems might well have allowed for a better real-time understanding of the unfolding of events, upon arrival of evacuees in shelters. Information and communication technologies have advanced since 2005, but predisaster staging and training on such technologies is still lacking.

  2. An Axisymmetric View of Concentric Eyewall Evolution in Hurricane Rita (2005)

    Science.gov (United States)

    2012-08-01

    of Hurricane Hugo (1989). Mon. Wea. Rev., 136, 1237–1259. Martinez, Y., G. Brunet, and M. K. Yau, 2010: On the dynamics of two-dimensional hurricane ...An Axisymmetric View of Concentric Eyewall Evolution in Hurricane Rita (2005) MICHAEL M. BELL Naval Postgraduate School, Monterey, California, and... Hurricane Research Division, Miami, Florida WEN-CHAU LEE National Center for Atmospheric Research,* Boulder, Colorado (Manuscript received 23 June 2011, in

  3. Pharmacological targeting of p53 through RITA is an effective antitumoral strategy for malignant pleural mesothelioma.

    Science.gov (United States)

    Di Marzo, Domenico; Forte, Iris Maria; Indovina, Paola; Di Gennaro, Elena; Rizzo, Valeria; Giorgi, Francesca; Mattioli, Eliseo; Iannuzzi, Carmelina Antonella; Budillon, Alfredo; Giordano, Antonio; Pentimalli, Francesca

    2014-01-01

    Malignant mesothelioma, a very aggressive tumor associated to asbestos exposure, is expected to increase in incidence, and unfortunately, no curative modality exists. Reactivation of p53 is a new attractive antitumoral strategy. p53 is rarely mutated in mesothelioma, but it is inactivated in most tumors by the lack of p14(ARF). Here, we evaluated the feasibility of this approach in pleural mesothelioma by testing RITA and nutlin-3, two molecules able to restore p53 function through a different mechanism, on a panel of mesothelioma cell lines representing the epithelioid (NCI-H28, NCI-H2452, IST-MES 2), biphasic (MSTO-211H), and sarcomatoid (NCI-H2052) histotypes compared with the normal mesothelial HMC-hTERT. RITA triggered robust caspase-dependent apoptosis specifically in epithelioid and biphasic mesothelioma cell lines, both through wild-type and mutant p53, concomitant to p21 downregulation. Conversely, nutlin-3 induced a p21-dependent growth arrest, rather than apoptosis, and was slightly toxic on HMC-hTERT.   Interestingly, we identified a previously undetected point mutation of p53 (p.Arg249Ser) in IST-MES 2, and showed that RITA is also able to reactivate this p53 mutant protein and its apoptotic function. RITA reduced tumor growth in a MSTO-211H-derived xenograft model of mesothelioma and synergized with cisplatin, which is the mainstay of treatment for this tumor. Our data indicate that reactivation of p53 and concomitant p21 downregulation effectively induce cell death in mesothelioma, a tumor characterized by a high intrinsic resistance to apoptosis. Altogether, our findings provide the preclinical framework supporting the use of p53-reactivating agents alone, or in combination regimens, to improve the outcome of patients with mesothelioma.

  4. Building and Managing Electronic Resources in Digital Era in India with Special Reference to IUCAA and NIV, Pune: A Comparative Case Study

    Science.gov (United States)

    Sahu, H. K.; Singh, S. N.

    2015-04-01

    This paper discusses and presents a comparative case study of two libraries in Pune, India, Inter-University Centre for Astronomy and Astrophysics and Information Centre and Library of National Institute of Virology (Indian Council of Medical Research). It compares how both libraries have managed their e-resource collections, including acquisitions, subscriptions, and consortia arrangements, while also developing a collection of their own resources, including pre-prints and publications, video lectures, and other materials in an institutional repository. This study illustrates how difficult it is to manage electronic resources in a developing country like India, even though electronic resources are used more than print resources. Electronic resource management can be daunting, but with a systematic approach, various problems can be solved, and use of the materials will be enhanced.

  5. The level of the usage of the human resource information system and electronic recruitment in Croatian companies

    Directory of Open Access Journals (Sweden)

    Snježana Pivac

    2014-12-01

    Full Text Available Performing business according to contemporary requirements influences companies for continuous usage of modern managerial tools, such as a human resource information system (HRIS and electronic recruitment (ER. Human resources have been recognised as curtail resources and the main source of a competitive advantage in creation of successful business performance. In order to attract and select the top employees, companies use quality information software for attracting internal ones, and electronic recruitment for attracting the best possible external candidates. The main aim of this paper is to research the level of the usage of HRIS and ER within medium-size and large Croatian companies. Moreover, the additional aim of this paper is to evaluate the relationship among the usage of these modern managerial tools and the overall success of human resource management within these companies. For the purpose of this paper, primary and secondary research has been conducted in order to reveal the level of the usage of HRIS and ER as well as the overall success of human resource management in Croatian companies. The companies’ classification (HRIS and ER is done by using the non-hierarchical k-means cluster method as well as the nonparametric Kruskal Wallis test. Further, the companies are ranked by the multicriteria PROMETHEE method. Relevant nonparametric tests are used for testing the overall companies’ HRM. Finally, binary logistic regression is estimated, relating binary variable HRM and HRIS development. After detailed research, it can be concluded that large Croatian companies apply HRIS in majority (with a positive relation to HRM performance, but still require certain degrees of its development.

  6. Effects of marsh pond terracing on coastal wintering waterbirds before and after Hurricane Rita.

    Science.gov (United States)

    O'Connell, Jessica L; Nyman, John A

    2011-11-01

    From February to March 2005-2006, we surveyed wintering waterbirds to test effects of terracing on coastal pond use before and after Hurricane Rita. Marsh terracing is intended to slow coastal marsh loss in the Chenier Plain by slowing marsh erosion and encouraging vegetation expansion. Terraces also increase marsh edge in ponds, possibly benefiting waterbirds. We monitored paired terraced and unterraced ponds in three sites within southwestern Louisiana's Chenier Plain. Waterbirds were 75% more numerous in terraced than unterraced ponds. Waterbird richness was similar among ponds when corrected for number of individuals, suggesting terracing increased bird density but did not provide habitat unique from unterraced ponds. Birds were 93% more numerous following Hurricane Rita, mostly due to an influx of migrating waterfowl. Year round residents were similar in number before and after Hurricane Rita. Resident richness did not differ among years after correcting for number of observed individuals. Wading and dabbling foragers were more abundant in terraced ponds and these two guilds represented 74% of birds observed. We detected no difference among ponds for other guilds, i.e., probing, aerial, and diving foragers. Increasing proportion of mash edge increased bird density disproportionately: On average ponds with 10% edge had 6 birds observed and ponds with 30% edge had 16 birds observed. Terraces increased habitat interspersion and were an effective tool for increasing numbers of wintering waterfowl and wading birds. The extent to which terraces were sustainable following hurricane forces is unknown.

  7. Effects of Marsh Pond Terracing on Coastal Wintering Waterbirds Before and After Hurricane Rita

    Science.gov (United States)

    O'Connell, Jessica L.; Nyman, John A.

    2011-11-01

    From February to March 2005-2006, we surveyed wintering waterbirds to test effects of terracing on coastal pond use before and after Hurricane Rita. Marsh terracing is intended to slow coastal marsh loss in the Chenier Plain by slowing marsh erosion and encouraging vegetation expansion. Terraces also increase marsh edge in ponds, possibly benefiting waterbirds. We monitored paired terraced and unterraced ponds in three sites within southwestern Louisiana's Chenier Plain. Waterbirds were 75% more numerous in terraced than unterraced ponds. Waterbird richness was similar among ponds when corrected for number of individuals, suggesting terracing increased bird density but did not provide habitat unique from unterraced ponds. Birds were 93% more numerous following Hurricane Rita, mostly due to an influx of migrating waterfowl. Year round residents were similar in number before and after Hurricane Rita. Resident richness did not differ among years after correcting for number of observed individuals. Wading and dabbling foragers were more abundant in terraced ponds and these two guilds represented 74% of birds observed. We detected no difference among ponds for other guilds, i.e., probing, aerial, and diving foragers. Increasing proportion of mash edge increased bird density disproportionately: On average ponds with 10% edge had 6 birds observed and ponds with 30% edge had 16 birds observed. Terraces increased habitat interspersion and were an effective tool for increasing numbers of wintering waterfowl and wading birds. The extent to which terraces were sustainable following hurricane forces is unknown.

  8. SISTEM INFORMASI DAN PENGOLAHAN DATA GAJI KARYAWAN PADA RITA PASARAYA KEBONDALEM PURWOKERTO

    Directory of Open Access Journals (Sweden)

    Nyoman Heddy Triyodanta

    2009-02-01

    Full Text Available Penelitian ini berjudul "Sistem Informasi dan Pengolahan Data GajiKaryawan pada Rita Pasaraya Kebondalem Purwokerto". Tujuan dari penelitian iniodalah untuk mengetahui prosedur sistem informasi pengolahan data gaji karynvanyang sedang berjalan atau sedang dipakai pada Rita Pasaraya KebondalemPurwoketo, yang masih dilakukan dengan proses manual dan pada akhirnyadirancang suatu sistem informasi yang lebih baik. Merancang sistem informasi yangberbasis komputer untuk membantu mengatasi kelemahan dalam pengolahan datamenjadi informasi sesuai dengan kebutuhan user. Hasil analisis menunjukkan bahwapengolahan data di Rita Pasaraya Kebondalem Purwokerto mosih menggunakansistem manual. Sistem yang baru yaitu komputerisasi akan lebih tepat biladipergunakan untuk kehandalan data gaji karyawan. Selain sistem yang baru secarakomputerisasi kedisiplinan pemakai juga perlu ditingkatkan, secara fasilitastambahan selain ruangan khusus yaitu adanya Air Condisioner (AC pada ruangkomputer untuk membuat awet secara perangkat keras komputer dan komputer dapatdihidupkan secara terus menerus. Sistem yang baru aknn menambah kepercayaanImryawan dan pihak lain yang membutuhkan karena akurat, tepat dan handal. Sertapengambilan keputusan tentang kondisi data gaji karyawan dapat lebih alatrat dancepat yang tidak lain dapat meningkatkan kinerja karyawan terhadap perusahaan.

  9. Sediment deposition from Hurricane Rita on Hackberry Beach chenier in southwestern Louisiana: Chapter 6E in Science and the storms-the USGS response to the hurricanes of 2005

    Science.gov (United States)

    Faulkner, Stephen; Barrow, Wylie; Doyle, Thomas; Baldwin, Michael; Michot, Thomas; Wells, Christopher; Jeske, Clint

    2007-01-01

    Hurricane Rita significantly impacted the chenier forests of southwestern Louisiana, an important habitat for Neotropical migratory birds. Sediment deposition was measured along transects at Hackberry Beach chenier, and Rita's effects on chenier structure and morphology were determined.

  10. MendelWeb: An Electronic Science/Math/History Resource for the WWW.

    Science.gov (United States)

    Blumberg, Roger B.

    This paper describes a hypermedia resource, called MendelWeb that integrates elementary biology, discrete mathematics, and the history of science. MendelWeb is constructed from Gregor Menders 1865 paper, "Experiments in Plant Hybridization". An English translation of Mendel's paper, which is considered to mark the birth of classical and…

  11. Helping Patrons Find Locally Held Electronic Resources: An Interlibrary Loan Perspective

    Science.gov (United States)

    Johnston, Pamela

    2016-01-01

    The University of North Texas Libraries provide extensive online access to academic journals through major vendor databases. As illustrated by interlibrary loan borrowing requests for items held in our databases, patrons often have difficulty navigating the available resources. In this study, the Interlibrary Loan staff used data gathered from the…

  12. QR Codes as Finding Aides: Linking Electronic and Print Library Resources

    Science.gov (United States)

    Kane, Danielle; Schneidewind, Jeff

    2011-01-01

    As part of a focused, methodical, and evaluative approach to emerging technologies, QR codes are one of many new technologies being used by the UC Irvine Libraries. QR codes provide simple connections between print and virtual resources. In summer 2010, a small task force began to investigate how QR codes could be used to provide information and…

  13. Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents.

    Science.gov (United States)

    Michaelis, M; Rothweiler, F; Agha, B; Barth, S; Voges, Y; Löschmann, N; von Deimling, A; Breitling, R; Doerr, H Wilhelm; Rödel, F; Speidel, D; Cinatl, J

    2012-04-05

    Adaptation of wild-type p53 expressing UKF-NB-3 cancer cells to the murine double minute 2 inhibitor nutlin-3 causes de novo p53 mutations at high frequency (13/20) and multi-drug resistance. Here, we show that the same cells respond very differently when adapted to RITA, a drug that, like nutlin-3, also disrupts the p53/Mdm2 interaction. All of the 11 UKF-NB-3 sub-lines adapted to RITA that we established retained functional wild-type p53 although RITA induced a substantial p53 response. Moreover, all RITA-adapted cell lines remained sensitive to nutlin-3, whereas only five out of 10 nutlin-3-adapted cell lines retained their sensitivity to RITA. In addition, repeated adaptation of the RITA-adapted sub-line UKF-NB-3(r)RITA(10 μM) to nutlin-3 resulted in p53 mutations. The RITA-adapted UKF-NB-3 sub-lines displayed no or less pronounced resistance to vincristine, cisplatin, and irradiation than nutlin-3-adapted UKF-NB-3 sub-lines. Furthermore, adaptation to RITA was associated with fewer changes at the expression level of antiapoptotic factors than observed with adaptation to nutlin-3. Transcriptomic analyses indicated the RITA-adapted sub-lines to be more similar at the gene expression level to the parental UKF-NB-3 cells than nutlin-3-adapted UKF-NB-3 sub-lines, which correlates with the observed chemotherapy and irradiation sensitivity phenotypes. In conclusion, RITA-adapted cells retain functional p53, remain sensitive to nutlin-3, and display a less pronounced resistance phenotype than nutlin-3-adapted cells.

  14. Eavesdropping on Electronic Guidebooks: Observing Learning Resources in Shared Listening Environments.

    Science.gov (United States)

    Woodruff, Allison; Aoki, Paul M.; Grinter, Rebecca E.; Hurst, Amy; Szymanski, Margaret H.; Thornton, James D.

    This paper describes an electronic guidebook, "Sotto Voce," that enables visitors to share audio information by eavesdropping on each others guidebook activity. The first section discusses the design and implementation of the guidebook device, key aspects of its user interface, the design goals for the audio environment, the eavesdropping…

  15. Development and evolution of The Knowledge Hub for Pathology and related electronic resources.

    Science.gov (United States)

    Hardwick, David F; Sinard, John; Silva, Fred

    2011-06-01

    The Knowledge Hub for Pathology was created to provide authenticated and validated knowledge for United States and Canadian Academy of Pathology members and pathologists worldwide with access to the Web. Using the material presented at the annual meeting of the United States and Canadian Academy of Pathology with existing selection and review procedures ensured that these criteria were met without added costly procedures. Further submissions for courses and research papers are provided in electronic format and funded by universities and hospitals for their creation; thus, the principal costs borne by the United States and Canadian Academy of Pathology are Web site-posting costs. Use has escalated rapidly from 2 million hits in 2002 to 51 million in 2009 with use by 35,000 pathologists from now a total of 180 countries. This true "freemium" model is a successful process as are more traditional continuing professional development course structures such as Anatomic Pathology Electronic Case Series, a "premium" model for learning electronically also sponsored by the United States and Canadian Academy of Pathology. Copyright © 2011 Elsevier Inc. All rights reserved.

  16. An Exploratory study on the use of LibAnswers to Resolve, Track and Monitor Electronic Resources Issues: The KAUST Library experience

    KAUST Repository

    Ramli, Rindra M.

    2017-01-01

    An Exploratory study on KAUST library use of LibAnswers in resolving electronic resources questions received in LibAnswers. It describes the findings of the questions received in LibAnswers. The author made suggestions based on the findings to improve the reference services in responding to e-resources questions.

  17. An Exploratory study on the use of LibAnswers to Resolve, Track and Monitor Electronic Resources Issues: The KAUST Library experience

    KAUST Repository

    Ramli, Rindra M.

    2017-05-03

    An Exploratory study on KAUST library use of LibAnswers in resolving electronic resources questions received in LibAnswers. It describes the findings of the questions received in LibAnswers. The author made suggestions based on the findings to improve the reference services in responding to e-resources questions.

  18. Designing a model of electronic human resource management’s implementation at the Ministry of Communications and Information Technology

    Directory of Open Access Journals (Sweden)

    Mirali Seyednaghavi

    2017-06-01

    Full Text Available : In the first phase of this study a model for electronic human resource management in government agencies based on new public services was explored by using software MAXQDA, then in the second phase, relationship between the elements of the theory were tested using software Smart PLS2. So the aim of this study is to design a model of electronic human resource management’s implementation at the Ministry of Communications and Information Technology. In this regard, according to Strauss and Corbin’s structured plan, five hypotheses were tested. Quantitative data analysis indicates that the pressures of the policies and global perspectives cause to move toward e-HRM. Among the contextual conditions macro structural mechanisms, considerations of actors, governance considerations have a significant impact on the strategy of new public services and therefore lead to the consequences of its implementation in public organizations. The findings suggest that e-HRM does not have a positive and meaningful impact on new public services, and in our country, although the recent political developments have somehow removed the gap between public policy makers, administrators, and the public, but there is still a long way to go.

  19. Preference and Use of Electronic Information and Resources by Blind/Visually Impaired in NCR Libraries in India

    Directory of Open Access Journals (Sweden)

    Shailendra Kumar

    2013-06-01

    Full Text Available This paper aims to determine the preference and use of electronic information and resources by blind/visually impaired users in the leading National Capital Region (NCR libraries of India. Survey methodology has been used as the basic research tool for data collection with the help of questionnaires. The 125 in total users surveyed in all the five libraries were selected randomly on the basis of willingness of the users with experience of working in digital environments to participate in the survey. The survey results were tabulated and analyzed with descriptive statistics methods using Excel software and 'Stata version 11'. The findings reveal that ICT have a positive impact in the lives of people with disabilities as it helps them to work independently and increases the level of confidence among them. The Internet is the most preferred medium of access to information among the majority of blind/visually impaired users. The 'Complexity of content available on the net' is found as the major challenge faced during Internet use by blind users of NCR libraries. 'Audio books on CDs/DVDs and DAISY books' are the most preferred electronic resources among the majority of blind/visually impaired users. This study will help the library professionals and organizations/institutions serving people with disabilities to develop effective library services for blind/visually impaired users in the digital environment on the basis of findings on information usage behavior in the study.

  20. Internet and electronic resources for inflammatory bowel disease: a primer for providers and patients.

    Science.gov (United States)

    Fortinsky, Kyle J; Fournier, Marc R; Benchimol, Eric I

    2012-06-01

    Patients with inflammatory bowel disease (IBD) are increasingly turning to the Internet to research their condition and engage in discourse on their experiences. This has resulted in new dynamics in the relationship between providers and their patients, with misinformation and advertising potentially presenting barriers to the cooperative patient-provider partnership. This article addresses important issues of online IBD-related health information and social media activity, such as quality, reliability, objectivity, and privacy. We reviewed the medical literature on the quality of online information provided to IBD patients, and summarized the most commonly accessed Websites related to IBD. We also assessed the activity on popular social media sites (such as Facebook, Twitter, and YouTube), and evaluated currently available applications for use by IBD patients and providers on mobile phones and tablets. Through our review of the literature and currently available resources, we developed a list of recommended online resources to strengthen patient participation in their care by providing reliable, comprehensive educational material. Copyright © 2011 Crohn's & Colitis Foundation of America, Inc.

  1. Effects of hurricanes Katrina and Rita on the chemistry of bottom sediments in Lake Pontchartrain, Louisiana, USA

    Science.gov (United States)

    Van Metre, P.C.; Horowitz, A.J.; Mahler, B.J.; Foreman, W.T.; Fuller, C.C.; Burkhardt, M.R.; Elrick, K.A.; Furlong, E.T.; Skrobialowski, S.C.; Smith, J.J.; Wilson, J.T.; Zaugg, S.D.

    2006-01-01

    The effects of Hurricanes Katrina and Rita and the subsequent unwatering of New Orleans, Louisiana, on the sediment chemistry of Lake Pontchartrain were evaluated by chemical analysis of samples of street mud and suspended and bottom sediments. The highest concentrations of urban-related elements and compounds (e.g., Pb, Zn, polycyclic aromatic hydrocarbons, and chlordane) in bottom sediments exceeded median concentrations in U.S. urban lakes and sediment-quality guidelines. The extent of the elevated concentrations was limited, however, to within a few hundred meters of the mouth of the 17th Street Canal, similar to results of historical assessments. Chemical and radionuclide analysis of pre- and post-Hurricane Rita samples indicates that remobilization of near-shore sediment by lake currents and storms is an ongoing process. The effects of Hurricanes Katrina and Rita on the sediment chemistry of Lake Pontchartrain are limited spatially and are most likely transitory. ?? 2006 American Chemical Society.

  2. Damage to offshore infrastructure in the Gulf of Mexico by hurricanes Katrina and Rita

    Science.gov (United States)

    Cruz, A. M.; Krausmann, E.

    2009-04-01

    The damage inflicted by hurricanes Katrina and Rita to the Gulf-of-Mexico's (GoM) oil and gas production, both onshore and offshore, has shown the proneness of industry to Natech accidents (natural hazard-triggered hazardous-materials releases). In order to contribute towards a better understanding of Natech events, we assessed the damage to and hazardous-materials releases from offshore oil and natural-gas platforms and pipelines induced by hurricanes Katrina and Rita. Data was obtained through a review of published literature and interviews with government officials and industry representatives from the affected region. We also reviewed over 60,000 records of reported hazardous-materials releases from the National Response Center's (NRC) database to identify and analyze the hazardous-materials releases directly attributed to offshore oil and gas platforms and pipelines affected by the two hurricanes. Our results show that hurricanes Katrina and Rita destroyed at least 113 platforms, and severely damaged at least 53 others. Sixty percent of the facilities destroyed were built 30 years ago or more prior to the adoption of the more stringent design standards that went into effect after 1977. The storms also destroyed 5 drilling rigs and severely damaged 19 mobile offshore drilling units (MODUs). Some 19 MODUs lost their moorings and became adrift during the storms which not only posed a danger to existing facilities but the dragging anchors also damaged pipelines and other infrastructure. Structural damage to platforms included toppling of sections, and tilting or leaning of platforms. Possible causes for failure of structural and non-structural components of platforms included loading caused by wave inundation of the deck. Failure of rigs attached to platforms was also observed resulting in significant damage to the platform or adjacent infrastructure, as well as damage to equipment, living quarters and helipads. The failures are attributable to tie-down components

  3. Electronic medical records in diabetes consultations: participants' gaze as an interactional resource.

    Science.gov (United States)

    Rhodes, Penny; Small, Neil; Rowley, Emma; Langdon, Mark; Ariss, Steven; Wright, John

    2008-09-01

    Two routine consultations in primary care diabetes clinics are compared using extracts from video recordings of interactions between nurses and patients. The consultations were chosen to present different styles of interaction, in which the nurse's gaze was either primarily toward the computer screen or directed more toward the patient. Using conversation analysis, the ways in which nurses shift both gaze and body orientation between the computer screen and patient to influence the style, pace, content, and structure of the consultation were investigated. By examining the effects of different levels of engagement between the electronic medical record and the embodied patient in the consultation room, we argue for the need to consider the contingent nature of the interface of technology and the person in the consultation. Policy initiatives designed to deliver what is considered best-evidenced practice are modified in the micro context of the interactions of the consultation.

  4. Granulometric composition study of mineral resources using opto-electronic devices and Elsieve software system

    Directory of Open Access Journals (Sweden)

    Kaminski Stanislaw

    2016-01-01

    Full Text Available The use of mechanical sieves has a great impact on measurement results because occurrence of anisometric particles causes undercounting the average size. Such errors can be avoided by using opto-electronic measuring devices that enable measurement of particles from 10 μm up to a few dozen millimetres in size. The results of measurement of each particle size fraction are summed up proportionally to its weight with the use of Elsieve software system and for every type of material particle-size distribution can be obtained. The software allows further statistical interpretation of the results. Beam of infrared radiation identifies size of particles and counts them precisely. Every particle is represented by an electronic impulse proportional to its size. Measurement of particles in aqueous suspension that replaces the hydrometer method can be carried out by using the IPS L analyser (range from 0.2 to 600 μm. The IPS UA analyser (range from 0.5 to 2000 μm is designed for measurement in the air. An ultrasonic adapter enables performing measurements of moist and aggregated particles from 0.5 to 1000 μm. The construction and software system allow to determine second dimension of the particle, its shape coefficient and specific surface area. The AWK 3D analyser (range from 0.2 to 31.5 mm is devoted to measurement of various powdery materials with subsequent determination of particle shape. The AWK B analyser (range from 1 to 130 mm measures materials of thick granulation and shape of the grains. The presented method of measurement repeatedly accelerates and facilitates study of granulometric composition.

  5. Lessons learned from the deadly sisters: drug and alcohol treatment disruption, and consequences from Hurricanes Katrina and Rita.

    Science.gov (United States)

    Maxwell, Jane Carlisle; Podus, Deborah; Walsh, David

    2009-01-01

    This paper reports on the effects of Hurricanes Katrina and Rita on drug and alcohol treatment in Texas in 2005-2006. Findings are based on a secondary analysis of administrative data on 567 hurricane-related admissions and on interview data from a sample of 20 staff in 11 treatment programs. Katrina evacuees differed from Rita clients in terms of demographics and primary problem substances and treatment needs, while the experiences of program staff and needed changes to improve disaster readiness were more similar. Additional systematic research is needed to document the intermediate and long-term impacts of the storms in these and other affected areas.

  6. Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma.

    Science.gov (United States)

    Saha, Manujendra N; Jiang, Hua; Yang, Yijun; Zhu, Xiaoyun; Wang, Xiaoming; Schimmer, Aaron D; Qiu, Lugui; Chang, Hong

    2012-01-01

    The low frequency of p53 alterations e.g., mutations/deletions (∼10%) in multiple myeloma (MM) makes this tumor type an ideal candidate for p53-targeted therapies. RITA is a small molecule which can induce apoptosis in tumor cells by activating the p53 pathway. We previously showed that RITA strongly activates p53 while selectively inhibiting growth of MM cells without inducing genotoxicity, indicating its potential as a drug lead for p53-targeted therapy in MM. However, the molecular mechanisms underlying the pro-apoptotic effect of RITA are largely undefined. Gene expression analysis by microarray identified a significant number of differentially expressed genes associated with stress response including c-Jun N-terminal kinase (JNK) signaling pathway. By Western blot analysis we further confirmed that RITA induced activation of p53 in conjunction with up-regulation of phosphorylated ASK-1, MKK-4 and c-Jun. These results suggest that RITA induced the activation of JNK signaling. Chromatin immunoprecipitation (ChIP) analysis showed that activated c-Jun binds to the activator protein-1 (AP-1) binding site of the p53 promoter region. Disruption of the JNK signal pathway by small interfering RNA (siRNA) against JNK or JNK specific inhibitor, SP-600125 inhibited the activation of p53 and attenuated apoptosis induced by RITA in myeloma cells carrying wild type p53. On the other hand, p53 transcriptional inhibitor, PFT-α or p53 siRNA not only inhibited the activation of p53 transcriptional targets but also blocked the activation of c-Jun suggesting the presence of a positive feedback loop between p53 and JNK. In addition, RITA in combination with dexamethasone, known as a JNK activator, displays synergistic cytotoxic responses in MM cell lines and patient samples. Our study unveils a previously undescribed mechanism of RITA-induced p53-mediated apoptosis through JNK signaling pathway and provides the rationale for combination of p53 activating drugs with JNK

  7. Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma.

    Directory of Open Access Journals (Sweden)

    Manujendra N Saha

    Full Text Available The low frequency of p53 alterations e.g., mutations/deletions (∼10% in multiple myeloma (MM makes this tumor type an ideal candidate for p53-targeted therapies. RITA is a small molecule which can induce apoptosis in tumor cells by activating the p53 pathway. We previously showed that RITA strongly activates p53 while selectively inhibiting growth of MM cells without inducing genotoxicity, indicating its potential as a drug lead for p53-targeted therapy in MM. However, the molecular mechanisms underlying the pro-apoptotic effect of RITA are largely undefined. Gene expression analysis by microarray identified a significant number of differentially expressed genes associated with stress response including c-Jun N-terminal kinase (JNK signaling pathway. By Western blot analysis we further confirmed that RITA induced activation of p53 in conjunction with up-regulation of phosphorylated ASK-1, MKK-4 and c-Jun. These results suggest that RITA induced the activation of JNK signaling. Chromatin immunoprecipitation (ChIP analysis showed that activated c-Jun binds to the activator protein-1 (AP-1 binding site of the p53 promoter region. Disruption of the JNK signal pathway by small interfering RNA (siRNA against JNK or JNK specific inhibitor, SP-600125 inhibited the activation of p53 and attenuated apoptosis induced by RITA in myeloma cells carrying wild type p53. On the other hand, p53 transcriptional inhibitor, PFT-α or p53 siRNA not only inhibited the activation of p53 transcriptional targets but also blocked the activation of c-Jun suggesting the presence of a positive feedback loop between p53 and JNK. In addition, RITA in combination with dexamethasone, known as a JNK activator, displays synergistic cytotoxic responses in MM cell lines and patient samples. Our study unveils a previously undescribed mechanism of RITA-induced p53-mediated apoptosis through JNK signaling pathway and provides the rationale for combination of p53 activating drugs with

  8. Dissolved and colloidal trace elements in the Mississippi River Delta outflow after Hurricanes Katrina and Rita

    Science.gov (United States)

    Shim, Moo-Joon; Swarzenski, Peter W.; Shiller, Alan M.

    2012-01-01

    The Mississippi River delta outflow region is periodically disturbed by tropical weather systems including major hurricanes, which can terminate seasonal bottom water hypoxia and cause the resuspension of shelf bottom sediments which could result in the injection of trace elements into the water column. In the summer of 2005, Hurricanes Katrina and Rita passed over the Louisiana Shelf within a month of each other. Three weeks after Rita, we collected water samples in the Mississippi River delta outflow, examining the distributions of trace elements to study the effect of Hurricanes Katrina and Rita. We observed limited stratification on the shelf and bottom waters that were no longer hypoxic. This resulted, for instance, in bottom water dissolved Mn being lower than is typically observed during hypoxia, but with concentrations still compatible with Mn–O2 trends previously reported. Interestingly, for no element were we able to identify an obvious effect of sediment resuspension on its distribution. In general, elemental distributions were compatible with previous observations in the Mississippi outflow system. Co and Re, which have not been reported for this system previously, showed behavior consistent with other systems: input for Co likely from desorption and conservative mixing for Re. For Cs, an element for which there is little information regarding its estuarine behavior, conservative mixing was also observed. Our filtration method, which allowed us to distinguish the dissolved (<0.02 μm) from colloidal (0.02–0.45 μm) phase, revealed significant colloidal fractions for Fe and Zn, only. For Fe, the colloidal phase was the dominant fraction and was rapidly removed at low salinity. Dissolved Fe, in contrast, persisted out to mid-salinities, being removed in a similar fashion to nitrate. This ability to distinguish the smaller Fe (likely dominantly organically complexed) from larger colloidal suspensates may be useful in better interpreting the

  9. The effect of proximity to hurricanes Katrina and Rita on subsequent hurricane outlook and optimistic bias.

    Science.gov (United States)

    Trumbo, Craig; Lueck, Michelle; Marlatt, Holly; Peek, Lori

    2011-12-01

    This study evaluated how individuals living on the Gulf Coast perceived hurricane risk after Hurricanes Katrina and Rita. It was hypothesized that hurricane outlook and optimistic bias for hurricane risk would be associated positively with distance from the Katrina-Rita landfall (more optimism at greater distance), controlling for historically based hurricane risk and county population density, demographics, individual hurricane experience, and dispositional optimism. Data were collected in January 2006 through a mail survey sent to 1,375 households in 41 counties on the coast (n = 824, 60% response). The analysis used hierarchal regression to test hypotheses. Hurricane history and population density had no effect on outlook; individuals who were male, older, and with higher household incomes were associated with lower risk perception; individual hurricane experience and personal impacts from Katrina and Rita predicted greater risk perception; greater dispositional optimism predicted more optimistic outlook; distance had a small effect but predicted less optimistic outlook at greater distance (model R(2) = 0.21). The model for optimistic bias had fewer effects: age and community tenure were significant; dispositional optimism had a positive effect on optimistic bias; distance variables were not significant (model R(2) = 0.05). The study shows that an existing measure of hurricane outlook has utility, hurricane outlook appears to be a unique concept from hurricane optimistic bias, and proximity has at most small effects. Future extension of this research will include improved conceptualization and measurement of hurricane risk perception and will bring to focus several concepts involving risk communication. © 2011 Society for Risk Analysis.

  10. Dissolved and colloidal trace elements in the Mississippi River delta outflow after Hurricanes Katrina and Rita

    Science.gov (United States)

    Shim, Moo-Joon; Swarzenski, Peter W.; Shiller, Alan M.

    2012-07-01

    The Mississippi River delta outflow region is periodically disturbed by tropical weather systems including major hurricanes, which can terminate seasonal bottom water hypoxia and cause the resuspension of shelf bottom sediments which could result in the injection of trace elements into the water column. In the summer of 2005, Hurricanes Katrina and Rita passed over the Louisiana Shelf within a month of each other. Three weeks after Rita, we collected water samples in the Mississippi River delta outflow, examining the distributions of trace elements to study the effect of Hurricanes Katrina and Rita. We observed limited stratification on the shelf and bottom waters that were no longer hypoxic. This resulted, for instance, in bottom water dissolved Mn being lower than is typically observed during hypoxia, but with concentrations still compatible with Mn-O2 trends previously reported. Interestingly, for no element were we able to identify an obvious effect of sediment resuspension on its distribution. In general, elemental distributions were compatible with previous observations in the Mississippi outflow system. Co and Re, which have not been reported for this system previously, showed behavior consistent with other systems: input for Co likely from desorption and conservative mixing for Re. For Cs, an element for which there is little information regarding its estuarine behavior, conservative mixing was also observed. Our filtration method, which allowed us to distinguish the dissolved (<0.02 μm) from colloidal (0.02-0.45 μm) phase, revealed significant colloidal fractions for Fe and Zn, only. For Fe, the colloidal phase was the dominant fraction and was rapidly removed at low salinity. Dissolved Fe, in contrast, persisted out to mid-salinities, being removed in a similar fashion to nitrate. This ability to distinguish the smaller Fe (likely dominantly organically complexed) from larger colloidal suspensates may be useful in better interpreting the bioavailablity

  11. Rita Thalmann (1926-2013), Pioneer of Women’s History

    OpenAIRE

    Hoock-Demarle, Marie-Claire

    2017-01-01

    Born in Nuremberg to a German-Jewish father and a Swiss-Jewish mother, Rita Thalmann fled the Nazi regime with her family in 1933, first taking refuge in Switzerland and then in France. After losing both her father (denounced and deported to Auschwitz), and her mother (who died of malnutrition while interned in Dijon), she survived the war through a support network organized by the headmistress of Dijon’s girls’ lycée, Marcelle Pardé, a member of the Resistance later deported to Ravensbrück. ...

  12. Inelastic neutron scattering experiments with the monochromatic imaging mode of the RITA-II spectrometer

    International Nuclear Information System (INIS)

    Bahl, C.R.H.; Lefmann, K.; Abrahamsen, A.B.; Ronnow, H.M.; Saxild, F.; Jensen, T.B.S.; Udby, L.; Andersen, N.H.; Christensen, N.B.; Jakobsen, H.S.; Larsen, T.; Haefliger, P.S.; Streule, S.; Niedermayer, Ch.

    2006-01-01

    Recently a monochromatic multiple data taking mode has been demonstrated for diffraction experiments using a RITA type cold neutron spectrometer with a multi-bladed analyser and a position-sensitive detector. Here, we show how this mode can be used in combination with a flexible radial collimator to perform real inelastic neutron scattering experiments. We present the results from inelastic powder, single crystal dispersion and single crystal constant energy mapping experiments. The advantages and complications of performing these experiments are discussed along with a comparison between the imaging mode and the traditional monochromatic focussing mode

  13. Inelastic neutron scattering experiments with the monochromatic imaging mode of the RITA-II spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Bahl, C.R.H. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark) and Department of Physics, Technical University of Denmark, DK-2800 Lyngby (Denmark)]. E-mail: christian.bahl@risoe.dk; Lefmann, K. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark)]. E-mail: kim.lefmann@risoe.dk; Abrahamsen, A.B. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Ronnow, H.M. [Laboratory for Neutron Scattering, Paul Scherrer Institute, CH-5232 Villigen (Switzerland); Saxild, F. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Jensen, T.B.S. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Udby, L. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Andersen, N.H. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Christensen, N.B. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Laboratory for Neutron Scattering, Paul Scherrer Institute, CH-5232 Villigen (Switzerland); Jakobsen, H.S. [Niels Bohr Institute for Astronomy, Physics and Geophysics, University of Copenhagen, DK-2100 Copenhagen (Denmark); Larsen, T. [Niels Bohr Institute for Astronomy, Physics and Geophysics, University of Copenhagen, DK-2100 Copenhagen (Denmark); Haefliger, P.S. [Laboratory for Neutron Scattering, Paul Scherrer Institute, CH-5232 Villigen (Switzerland); Streule, S.; Niedermayer, Ch. [Laboratory for Neutron Scattering, Paul Scherrer Institute, CH-5232 Villigen (Switzerland)

    2006-05-15

    Recently a monochromatic multiple data taking mode has been demonstrated for diffraction experiments using a RITA type cold neutron spectrometer with a multi-bladed analyser and a position-sensitive detector. Here, we show how this mode can be used in combination with a flexible radial collimator to perform real inelastic neutron scattering experiments. We present the results from inelastic powder, single crystal dispersion and single crystal constant energy mapping experiments. The advantages and complications of performing these experiments are discussed along with a comparison between the imaging mode and the traditional monochromatic focussing mode.

  14. The RITA spectrometer at Risø - Design considerations and recent results

    DEFF Research Database (Denmark)

    Clausen, K.N.; McMorrow, D.F.; Lefmann, K.

    1998-01-01

    In the new cold triple axis spectrometer RITA at Riso we have improved the front end by extensive use of state of the art optical elements and better shielding material. The analyser system is situated in one large open tank and consists of seven individually orientable PC(002) crystal analyser b...... by a study of the spin fluctuations in the high T-c superconductor La1.83Sr0.17CuO4. (C) 1998 Elsevier Science B.V. All rights reserved....

  15. RITA inhibits multiple myeloma cell growth through induction of p53-mediated caspase-dependent apoptosis and synergistically enhances nutlin-induced cytotoxic responses.

    Science.gov (United States)

    Saha, Manujendra N; Jiang, Hua; Mukai, Asuka; Chang, Hong

    2010-11-01

    Mutations or deletions of p53 are relatively rare in multiple myeloma (MM), at least in newly diagnosed patients. Thus, restoration of p53 tumor suppressor function in MM by blocking the inhibitory role of murine double minute 2 (MDM2) is a promising and applicable therapeutic strategy. RITA and nutlin are two new classes of small molecule MDM2 inhibitors that prevent the p53-MDM2 interaction. Earlier reports showed p53-dependent activity of RITA in solid tumors as well as in leukemias. We and others recently described nutlin-induced apoptosis in MM cells, but it remains unclear whether RITA exerts antimyeloma activity. Here, we found that RITA activates the p53 pathway and induces apoptosis in MM cell lines and primary MM samples, preferentially killing myeloma cells. The activation of p53 induced by RITA was mediated through modulation of multiple apoptotic regulatory proteins, including upregulation of a proapoptotic protein (NOXA), downregulation of an antiapoptotic protein, Mcl-1, and activation of caspases through extrinsic pathways. Moreover, a number of key p53-mediated apoptotic target genes were identified by gene expression profiling and further validated by quantitative real-time PCR. Importantly, the combination of RITA with nutlin displayed a strong synergism on growth inhibition with the combination index ranging from 0.56 to 0.82 in MM cells. Our data support further clinical evaluation of RITA as a potential novel therapeutic intervention in MM. ©2010 AACR.

  16. Environmental Impact Report from Santa Rita Hydroelectric Power Plant (Minas Gerais State - Brazil): technical strategic for its elaboration; Relatorio de Impacto Ambiental da Usina Hidreletrica da Santa Rita (MG): estrategica tecnica para sua elaboracao

    Energy Technology Data Exchange (ETDEWEB)

    Souza, J.A. de; Marques Neto, F P [Companhia Energetica de Minas Gerais (CEMIG), Belo Horizonte, MG (Brazil)

    1990-12-31

    The steps for developing the technical strategies used on the elaboration of Environmental Impact Report from Santa Rita Hydroelectric Power Plant, Minas Gerais State, are described, including the influence area, technical requirements, impact identification, technical selection of mitigative measures, impact meaning and strategy for evaluating the identified impacts. (C.G.C.).

  17. Green Supply Chain Collaboration for Fashionable Consumer Electronics Products under Third-Party Power Intervention—A Resource Dependence Perspective

    Directory of Open Access Journals (Sweden)

    Jiuh-Biing Sheu

    2014-05-01

    Full Text Available Under third-party power intervention (TPPI, which increases uncertainty in task environments, complex channel power interplays and restructuring are indispensable among green supply chain members as they move toward sustainable collaborative relationships for increased viability and competitive advantage. From the resource dependence perspective, this work presents a novel conceptual model to investigate the influence of political and social power on channel power restructuring and induced green supply chain collaboration in brander-retailer bidirectional green supply chains of fashionable consumer electronics products (FCEPs. An FCEP refers to the consumer electronics product (e.g., personal computers, mobile phones, computer notebooks, and game consoles with the features of a well-known brand associated, a short product lifecycle, timely and fashionable design fit for market trends, and quick responsiveness to the variations of market demands. The proposed model is tested empirically using questionnaire data obtained from retailers in the FCEP brander-retailer distribution channels. Analytical results reveal that as an extension of political and social power, TPPI positively affects the reciprocal interdependence of dyadic members and reduces power asymmetry, thereby enhancing the collaborative relationship of dyadic members and leading to improved green supply chain performance. Therein, reciprocal interdependence underlying collaborative relationship is the key to reducing the external environmental uncertainties in the TPPI context.

  18. Structure-function analysis of RBP-J-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genes.

    Science.gov (United States)

    Tabaja, Nassif; Yuan, Zhenyu; Oswald, Franz; Kovall, Rhett A

    2017-06-23

    The Notch pathway is a cell-to-cell signaling mechanism that is essential for tissue development and maintenance, and aberrant Notch signaling has been implicated in various cancers, congenital defects, and cardiovascular diseases. Notch signaling activates the expression of target genes, which are regulated by the transcription factor CSL (CBF1/RBP-J, Su(H), Lag-1). CSL interacts with both transcriptional corepressor and coactivator proteins, functioning as both a repressor and activator, respectively. Although Notch activation complexes are relatively well understood at the structural level, less is known about how CSL interacts with corepressors. Recently, a new RBP-J (mammalian CSL ortholog)-interacting protein termed RITA has been identified and shown to export RBP-J out of the nucleus, thereby leading to the down-regulation of Notch target gene expression. However, the molecular details of RBP-J/RITA interactions are unclear. Here, using a combination of biochemical/cellular, structural, and biophysical techniques, we demonstrate that endogenous RBP-J and RITA proteins interact in cells, map the binding regions necessary for RBP-J·RITA complex formation, and determine the X-ray structure of the RBP-J·RITA complex bound to DNA. To validate the structure and glean more insights into function, we tested structure-based RBP-J and RITA mutants with biochemical/cellular assays and isothermal titration calorimetry. Whereas our structural and biophysical studies demonstrate that RITA binds RBP-J similarly to the RAM (RBP-J-associated molecule) domain of Notch, our biochemical and cellular assays suggest that RITA interacts with additional regions in RBP-J. Taken together, these results provide molecular insights into the mechanism of RITA-mediated regulation of Notch signaling, contributing to our understanding of how CSL functions as a transcriptional repressor of Notch target genes. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  19. The management of online resources and long-term saving of electronic documents by transfer into the digital space

    Directory of Open Access Journals (Sweden)

    Marius Daniel MAREŞ

    2011-12-01

    The electronic archive refers to the electronic storage system, along with the totality of electronic-type stored documents, while using as storage support any environment that can support storing and from which an electronic document can be presented.

  20. saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription.

    Science.gov (United States)

    Portnoy, Victoria; Lin, Szu Hua Sharon; Li, Kathy H; Burlingame, Alma; Hu, Zheng-Hui; Li, Hao; Li, Long-Cheng

    2016-03-01

    Small activating RNAs (saRNAs) targeting specific promoter regions are able to stimulate gene expression at the transcriptional level, a phenomenon known as RNA activation (RNAa). It is known that RNAa depends on Ago2 and is associated with epigenetic changes at the target promoters. However, the precise molecular mechanism of RNAa remains elusive. Using human CDKN1A (p21) as a model gene, we characterized the molecular nature of RNAa. We show that saRNAs guide Ago2 to and associate with target promoters. saRNA-loaded Ago2 facilitates the assembly of an RNA-induced transcriptional activation (RITA) complex, which, in addition to saRNA-Ago2 complex, includes RHA and CTR9, the latter being a component of the PAF1 complex. RITA interacts with RNA polymerase II to stimulate transcription initiation and productive elongation, accompanied by monoubiquitination of histone 2B. Our results establish the existence of a cellular RNA-guided genome-targeting and transcriptional activation mechanism and provide important new mechanistic insights into the RNAa process.

  1. Secondary eyewall formation in WRF simulations of Hurricanes Rita and Katrina (2005)

    Science.gov (United States)

    Abarca, Sergio F.; Corbosiero, Kristen L.

    2011-04-01

    An analysis is presented of two high-resolution hurricane simulations of Katrina and Rita (2005) that exhibited secondary eyewall formation (SEF). The results support the notion of vortex Rossby waves (VRWs) having an important role in SEF and suggest that VRW activity is a defining aspect of the moat. SEF occurs at a radius of ˜65 (80) km in Katrina (Rita), close to the hypothesized stagnation radius of VRWs. VRW activity appears to be the result of eye-eyewall mixing events, themselves a product of the release of barotropic instability. The convection in the radial region that becomes the moat is mainly in the form of VRWs propagating radially outward from the primary eyewall until the negative radial gradient of potential vorticity is no longer conducive for their propagation. These convectively coupled waves, originating and being expelled from the eyewall, are rotation dominated and have the coherency necessary to survive their passage through the strain-dominated region outside the eyewall.

  2. From the incident command center oil spills from Hurricanes Katrina and Rita

    Energy Technology Data Exchange (ETDEWEB)

    Guidry, R.J. [Lousiana Oil Spill Coordinator' s Office, Baton Rouge, LA (United States)

    2006-07-01

    Approximately 30.2 million litres of oil were discharged during Hurricanes Katrina and Rita. A total of 230 incidents were reported to the state's spill response community, including ruptured pipelines, damaged and moved storage tanks, refineries, and sunken vessels. By January 2006, industry had reported the recovery of 14.7 million litres of oil. After Hurricane Rita, a further 234 off- and onshore incidents were reported. This paper presented a chronology from August 26 2005 through to June 2006 of clean-up activities for both hurricanes, with specific reference to logistic and communications issues associated with working in environments that are difficult to access due to damaged transportation infrastructure. An outline of the Louisiana Oil Spill Coordinator's Office's role in the incidents was presented, as well as an overview of the Louisiana State Contingency Plan. It was noted that the lack of communications systems caused considerable difficulties for responders. It was concluded that responses to hurricanes can be made more effective by having all response communities incident command structure (ICS)-trained with a thorough knowledge of the National Response Plan as it relates to the National Contingency Plan. Ensuring that plans are operational, having clear lines of authority on all hurricane-related issues, and having a robust communications plan were recommended, as well as the ability to respond without communications.

  3. The RITA spectrometer at Risø - design considerations and recent results

    Science.gov (United States)

    Clausen, K. N.; McMorrow, D. F.; Lefmann, K.; Aeppli, G.; Mason, T. E.; Schröder, A.; Issikii, M.; Nohara, M.; Takagi, H.

    In the new cold triple axis spectrometer RITA at Risø we have improved the front end by extensive use of state of the art optical elements and better shielding material. The analyser system is situated in one large open tank and consists of seven individually orientable PG(002) crystal analyser blades, and a 170 mm by 120 mm 2 areas sensitive micro-strip detector. In comparison to the old TAS6 spectrometer we have obtained a factor 2-5 gain in intensity on the sample, a substantially lower background, much more flexibility for optimising the instrument and the possibility to go beyond simple point-by-point inspection. The excellent performance of RITA in the standard TAS mode is exemplified by a study of the dynamics of ≈ 15 nm hematite (α-Fe 2O 3) nano-particles, and utilisation of horizontal and vertical focusing modes to study two dimensional systems is illustrated by a study of the spin fluctuations in the high Tc superconductor La 1.83Sr 0.17CuO 4.

  4. From the incident command center oil spills from Hurricanes Katrina and Rita

    International Nuclear Information System (INIS)

    Guidry, R.J.

    2006-01-01

    Approximately 30.2 million litres of oil were discharged during Hurricanes Katrina and Rita. A total of 230 incidents were reported to the state's spill response community, including ruptured pipelines, damaged and moved storage tanks, refineries, and sunken vessels. By January 2006, industry had reported the recovery of 14.7 million litres of oil. After Hurricane Rita, a further 234 off- and onshore incidents were reported. This paper presented a chronology from August 26 2005 through to June 2006 of clean-up activities for both hurricanes, with specific reference to logistic and communications issues associated with working in environments that are difficult to access due to damaged transportation infrastructure. An outline of the Louisiana Oil Spill Coordinator's Office's role in the incidents was presented, as well as an overview of the Louisiana State Contingency Plan. It was noted that the lack of communications systems caused considerable difficulties for responders. It was concluded that responses to hurricanes can be made more effective by having all response communities incident command structure (ICS)-trained with a thorough knowledge of the National Response Plan as it relates to the National Contingency Plan. Ensuring that plans are operational, having clear lines of authority on all hurricane-related issues, and having a robust communications plan were recommended, as well as the ability to respond without communications

  5. Electronic structure of Pu carbides: photoelectron spectroscopy

    Czech Academy of Sciences Publication Activity Database

    Gouder, T.; Havela, L.; Shick, Alexander; Huber, F.

    2008-01-01

    Roč. 403, č. 5-9 (2008), s. 852-853 ISSN 0921-4526 R&D Projects: GA AV ČR(CZ) IAA100100530 Grant - others:EU(XE) RITA -CT-2006-026176 Institutional research plan: CEZ:AV0Z10100520 Keywords : photoemission * electronic structure * plutonium Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 0.822, year: 2008

  6. Mental Health, Substance Use, and Adaptive Coping among Social Work Students in the Aftermath of Hurricanes Katrina and Rita

    Science.gov (United States)

    Lemieux, Catherine M.; Plummer, Carol A.; Richardson, Roslyn; Simon, Cassandra E.; Ai, Amy L.

    2010-01-01

    The current study examined mental health symptomology, substance use, and adaptive coping among 416 social work students following Hurricanes Katrina and Rita. Among participants, 47% scored at or above the clinical level for depression, with 6% of students showing clinical PTSD-like symptoms, and 16.9% reporting substance use. Two thirds (66.9%)…

  7. Meie seast on lahkunud saksa keele tõlk Rita Tasa : [3.12.1930-16.07.2007

    Index Scriptorium Estoniae

    2007-01-01

    Järelhüüe kirjandusteadlasele, Tartu Ülikooli saksa kirjanduse õppejõule, Tallinna Pedagoogilise Instituudi saksa ja maailmakirjanduse õppejõule, saksa keele kadeedri juhatajale, saksa, šveitsi ning austria kirjanduse tõlkijale Rita Tasale

  8. Environmental Impact Report from Santa Rita Hydroelectric Power Plant (Minas Gerais State - Brazil): technical strategic for its elaboration

    International Nuclear Information System (INIS)

    Souza, J.A. de; Marques Neto, F.P.

    1989-01-01

    The steps for developing the technical strategies used on the elaboration of Environmental Impact Report from Santa Rita Hydroelectric Power Plant, Minas Gerais State, are described, including the influence area, technical requirements, impact identification, technical selection of mitigative measures, impact meaning and strategy for evaluating the identified impacts. (C.G.C.)

  9. Rescue of p53 function by small-molecule RITA in cervical carcinoma by blocking E6-mediated degradation.

    Science.gov (United States)

    Zhao, Carolyn Ying; Szekely, Laszlo; Bao, Wenjie; Selivanova, Galina

    2010-04-15

    Proteasomal degradation of p53 by human papilloma virus (HPV) E6 oncoprotein plays a pivotal role in the survival of cervical carcinoma cells. Abrogation of HPV-E6-dependent p53 destruction can therefore be a good strategy to combat cervical carcinomas. Here, we show that a small-molecule reactivation of p53 and induction of tumor cell apoptosis (RITA) is able to induce the accumulation of p53 and rescue its tumor suppressor function in cells containing high-risk HPV16 and HPV18 by inhibiting HPV-E6-mediated proteasomal degradation. RITA blocks p53 ubiquitination by preventing p53 interaction with E6-associated protein, required for HPV-E6-mediated degradation. RITA activates the transcription of proapoptotic p53 targets Noxa, PUMA, and BAX, and repressed the expression of pro-proliferative factors CyclinB1, CDC2, and CDC25C, resulting in p53-dependent apoptosis and cell cycle arrest. Importantly, RITA showed substantial suppression of cervical carcinoma xenografts in vivo. These results provide a proof of principle for the treatment of cervical cancer in a p53-dependent manner by using small molecules that target p53. (c)2010 AACR.

  10. Traumatic Loss and Natural Disaster: A Case Study of a School-Based Response to Hurricanes Katrina and Rita

    Science.gov (United States)

    Clettenberg, Stacey; Gentry, Judy; Held, Matthew; Mock, Lou Ann

    2011-01-01

    This article tracks the trajectory and impact of Hurricanes Katrina and Rita on the communities of Houston/Harris County, Texas, USA, the schools, children, and families; along with the community partnerships that addressed the trauma and upheaval. Following the influx of individuals and families who were displaced by Hurricanes Katrina and Rita…

  11. Positive Traits versus Previous Trauma: Racially Different Correlates with PTSD Symptoms among Hurricane Katrina-Rita Volunteers

    Science.gov (United States)

    Ai, Amy L.; Plummer, Carol; Kanno, Hanae; Heo, Grace; Appel, Hoa B.; Simon, Cassandra E.; Spigner, Clarence

    2011-01-01

    This study compared risks and protective factors for acquiring symptoms of posttraumatic stress disorder (PTSD) between African-American (n = 299) and European-American (n = 206) student volunteers 3 months after Hurricanes Katrina and Rita (H-KR). Respondents retrospectively provided information on peritraumatic emotional reactions and previous…

  12. Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer

    Directory of Open Access Journals (Sweden)

    Espinoza-Fonseca L Michel

    2005-09-01

    Full Text Available Abstract Background The use of low-molecular-weight, non-peptidic molecules that disrupt the interaction between the p53 tumor suppressor and its negative regulator MDM2 has provided a promising alternative for the treatment of different types of cancer. Among these compounds, RITA (reactivation of p53 and induction of tumor cell apoptosis has been shown to be effective in the selective induction of apoptosis, and this effect is due to its binding to the p53 tumor suppressor. Since biological systems are highly dynamic and MDM2 may bind to different regions of p53, new alternatives should be explored. On this basis, the computational "blind docking" approach was employed in this study to see whether RITA would bind to MDM2. Results It was observed that RITA binds to the MDM2 p53 transactivation domain-binding cleft. Thus, RITA can be used as a lead compound for designing improved "multi-target" drugs. This novel strategy could provide enormous benefits to enable effective anti-cancer strategies. Conclusion This study has demonstrated that a single molecule can target at least two different proteins related to the same disease.

  13. Rising Above the Water: New Orleans Implements Energy Efficiency and Sustainability Practices Following Hurricanes Katrina and Rita (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2012-07-01

    This fact sheet describes the technical assistance that the U.S. Department of Energy, through its National Renewable Energy Laboratory, provided to New Orleans, Louisiana, which helped the city incorporate energy efficiency into its rebuilding efforts for K-12 schools and homes following Hurricanes Katrina and Rita. NREL also provided support and analysis on energy policy efforts.

  14. RITA can induce cell death in p53-defective cells independently of p53 function via activation of JNK/SAPK and p38.

    Science.gov (United States)

    Weilbacher, A; Gutekunst, M; Oren, M; Aulitzky, W E; van der Kuip, H

    2014-07-10

    Significant advances have been made in the development of small molecules blocking the p53/MDM2 interaction. The Mdm2 inhibitor Nutlin-3 is restricted to tumors carrying wtp53. In contrast, RITA, a compound that binds p53, has recently been shown also to restore transcriptional functions of mtp53. As more than 50% of solid tumors carry p53 mutations, RITA promises to be a more effective therapeutic strategy than Nutlin-3. We investigated effects of RITA on apoptosis, cell cycle and induction of 45 p53 target genes in a panel of 14 cell lines from different tumor entities with different p53 status as well as primary lymphocytes and fibroblasts. Nine cell strains expressed wtp53, four harbored mtp53, and three were characterized by the loss of p53 protein. A significant induction of cell death upon RITA was observed in 7 of 16 cell lines. The nonmalignant cells in our panel were substantially less sensitive. We found that in contrast to Nultin-3, RITA is capable to induce cell death not only in tumor cells harboring wtp53 and mtp53 but also in p53-null cells. Importantly, whereas p53 has a central role for RITA-mediated effects in wtp53 cells, neither p53 nor p63 or p73 were essential for the RITA response in mtp53 or p53-null cells in our panel demonstrating that besides the known p53-dependent action of RITA in wtp53 cells, RITA can induce cell death also independently of p53 in cells harboring defective p53. We identified an important role of both p38 and JNK/SAPK for sensitivity to RITA in these cells leading to a typical caspase- and BAX/BAK-dependent mitochondrial apoptosis. In conclusion, our data demonstrate that RITA can induce apoptosis through p38 and JNK/SAPK not only in tumor cells harboring wtp53 and mtp53 but also in p53-null cells, making RITA an interesting tumor-selective drug.

  15. A randomized comparison of the Saphenous Vein Versus Right Internal Thoracic Artery as a Y-Composite Graft (SAVE RITA) trial: One-year angiographic results and mid-term clinical outcomes.

    Science.gov (United States)

    Kim, Ki-Bong; Hwang, Ho Young; Hahn, Seokyung; Kim, Jun Sung; Oh, Se Jin

    2014-09-01

    The Saphenous Vein Versus Right Internal Thoracic Artery as a Y-Composite Graft (SAVE RITA) trial was designed to evaluate the noninferiority of the saphenous vein (SV) compared with the right internal thoracic artery ([R]ITA) used as a Y-composite graft. A total of 224 patients who had undergone off-pump revascularization for multivessel coronary artery disease using the SV or RITA as a Y-composite graft based on the in situ left ITA were assigned randomly to the SV Y-composite graft (SV group, n = 112) or free RITA Y-composite graft (RITA group, n = 112). The primary endpoint was the 1-year angiographic patency rate of the second limb conduits (SV or RITA). Postoperative 1-year coronary angiograms were performed in 215 patients (SV group, 108; RITA group, 107). The overall graft patency rate was 97.4% (745 of 765) at 1 year (97.9% in the SV group vs 96.9% in the RITA group, P = .362). The primary endpoint of the study, the 1-year patency rate of the SV composite grafts, was 97.1% (238 of 245) and was noninferior to that of the RITA composite grafts (97.1% [198 of 204]) with a 95% lower confidence limit of -2.6% (P RITA composite grafts in terms of the 1-year angiographic patency rates. Copyright © 2014 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

  16. p53-dependent inhibition of TrxR1 contributes to the tumor-specific induction of apoptosis by RITA.

    Science.gov (United States)

    Hedström, Elisabeth; Eriksson, Sofi; Zawacka-Pankau, Joanna; Arnér, Elias S J; Selivanova, Galina

    2009-11-01

    Thioredoxin reductase 1 (TrxR1) is a key regulator in many redox-dependent cellular pathways, and is often overexpressed in cancer. Several studies have identified TrxR1 as a potentially important target for anticancer therapy. The low molecular weight compound RITA (NSC 652287) binds p53 and induces p53-dependent apoptosis. Here we found that RITA also targets TrxR1 by non-covalent binding, followed by inhibition of its activity in vitro and by inhibition of TrxR activity in cancer cells. Interestingly, a novel approximately 130 kDa form of TrxR1, presumably representing a stable covalently linked dimer, and an increased generation of reactive oxygen species (ROS) were induced by RITA in cancer cells in a p53-dependent manner. Similarly, the gold-based TrxR inhibitor auranofin induced apoptosis related to oxidative stress, but independently of p53 and without apparent induction of the approximately 130 kDa form of TrxR1. In contrast to the effects observed in cancer cells, RITA did not inhibit TrxR or ROS formation in normal fibroblasts (NHDF). The inhibition of TrxR1 can sensitize tumor cells to agents that induce oxidative stress and may directly trigger cell death. Thus, our results suggest that a unique p53-dependent effect of RITA on TrxR1 in cancer cells might synergize with p53-dependent induction of pro-apoptotic genes and oxidative stress, thereby leading to a robust induction of cancer cell death, without affecting non-transformed cells.

  17. Development of an Electronic Medical Record Based Alert for Risk of HIV Treatment Failure in a Low-Resource Setting

    Science.gov (United States)

    Puttkammer, Nancy; Zeliadt, Steven; Balan, Jean Gabriel; Baseman, Janet; Destiné, Rodney; Domerçant, Jean Wysler; France, Garilus; Hyppolite, Nathaelf; Pelletier, Valérie; Raphael, Nernst Atwood; Sherr, Kenneth; Yuhas, Krista; Barnhart, Scott

    2014-01-01

    Background The adoption of electronic medical record systems in resource-limited settings can help clinicians monitor patients' adherence to HIV antiretroviral therapy (ART) and identify patients at risk of future ART failure, allowing resources to be targeted to those most at risk. Methods Among adult patients enrolled on ART from 2005–2013 at two large, public-sector hospitals in Haiti, ART failure was assessed after 6–12 months on treatment, based on the World Health Organization's immunologic and clinical criteria. We identified models for predicting ART failure based on ART adherence measures and other patient characteristics. We assessed performance of candidate models using area under the receiver operating curve, and validated results using a randomly-split data sample. The selected prediction model was used to generate a risk score, and its ability to differentiate ART failure risk over a 42-month follow-up period was tested using stratified Kaplan Meier survival curves. Results Among 923 patients with CD4 results available during the period 6–12 months after ART initiation, 196 (21.2%) met ART failure criteria. The pharmacy-based proportion of days covered (PDC) measure performed best among five possible ART adherence measures at predicting ART failure. Average PDC during the first 6 months on ART was 79.0% among cases of ART failure and 88.6% among cases of non-failure (pART initiation were added to PDC, the risk score differentiated between those who did and did not meet failure criteria over 42 months following ART initiation. Conclusions Pharmacy data are most useful for new ART adherence alerts within iSanté. Such alerts offer potential to help clinicians identify patients at high risk of ART failure so that they can be targeted with adherence support interventions, before ART failure occurs. PMID:25390044

  18. Development of an electronic medical record based alert for risk of HIV treatment failure in a low-resource setting.

    Directory of Open Access Journals (Sweden)

    Nancy Puttkammer

    Full Text Available The adoption of electronic medical record systems in resource-limited settings can help clinicians monitor patients' adherence to HIV antiretroviral therapy (ART and identify patients at risk of future ART failure, allowing resources to be targeted to those most at risk.Among adult patients enrolled on ART from 2005-2013 at two large, public-sector hospitals in Haiti, ART failure was assessed after 6-12 months on treatment, based on the World Health Organization's immunologic and clinical criteria. We identified models for predicting ART failure based on ART adherence measures and other patient characteristics. We assessed performance of candidate models using area under the receiver operating curve, and validated results using a randomly-split data sample. The selected prediction model was used to generate a risk score, and its ability to differentiate ART failure risk over a 42-month follow-up period was tested using stratified Kaplan Meier survival curves.Among 923 patients with CD4 results available during the period 6-12 months after ART initiation, 196 (21.2% met ART failure criteria. The pharmacy-based proportion of days covered (PDC measure performed best among five possible ART adherence measures at predicting ART failure. Average PDC during the first 6 months on ART was 79.0% among cases of ART failure and 88.6% among cases of non-failure (p<0.01. When additional information including sex, baseline CD4, and duration of enrollment in HIV care prior to ART initiation were added to PDC, the risk score differentiated between those who did and did not meet failure criteria over 42 months following ART initiation.Pharmacy data are most useful for new ART adherence alerts within iSanté. Such alerts offer potential to help clinicians identify patients at high risk of ART failure so that they can be targeted with adherence support interventions, before ART failure occurs.

  19. Innovative direct energy conversion systems using electronic adiabatic processes of electron fluid in solid conductors: new plants of electrical power and hydrogen gas resources without environmental pollutions

    International Nuclear Information System (INIS)

    Kondoh, Y.; Kondo, M.; Shimoda, K.; Takahashi, T.

    2001-07-01

    It is shown that using a novel recycling process of the environmental thermal energy, innovative permanent auto-working direct energy converter systems (PA-DEC systems) from the environmental thermal to electrical and/or chemical potential (TE/CP) energies, abbreviated as PA-TE/CP-DEC systems, can be used for new auto-working electrical power plants and the plants of the compressible and conveyable hydrogen gas resources at various regions in the whole world, with contributions to the world peace and the economical development in the south part of the world. It is shown that the same physical mechanism by free electrons and electrical potential determined by temperature in conductors, which include semiconductors, leads to the Peltier effect and the Seebeck one. It is experimentally clarified that the long distance separation between two π type elements of the heat absorption (HAS) and the production one (HPS) of the Peltier effect circuit system or between the higher temperature side (HTS) and the lower one (LTS) of the Seebeck effect circuit one does not change in the whole for the both effects. By using present systems, we do not need to use petrified fuels such as coals, oils, and natural gases in order to decrease the greenhouse effect by the CO 2 surrounding the earth. Furthermore, we do not need plats of nuclear fissions that left radiating wastes, i.e., with no environmental pollutions. The PA-TE/CP-DEC systems can be applicable for several km scale systems to the micro ones, such as the plants of the electrical power, the compact transportable hydrogen gas resources, a large heat energy container, which can be settled at far place from thermal energy absorbing area, the refrigerators, the air conditioners, home electrical apparatuses, and further the computer elements. It is shown that the simplest PA-TE/CP-DEC system can be established by using only the Seebeck effect components and the resolving water ones. It is clarified that the externally applied

  20. Consumer reports [electronic resource

    National Research Council Canada - National Science Library

    1942-01-01

    ... only. A limited number of selected reports, advice on product selection and safety alerts are freely available, as are a five year listing of product recalls, a listing of major consumer product...

  1. Morphological responses of the Wax Lake Delta, Louisiana, to Hurricanes Rita

    Directory of Open Access Journals (Sweden)

    Fei Xing

    2017-12-01

    Full Text Available This study examines the morphodynamic response of a deltaic system to extreme weather events. The Wax Lake Delta (WLD in Louisiana, USA, is used to illustrate the impact of extreme events (hurricanes on a river-dominated deltaic system. Simulations using the open source Delft3D model reveal that Hurricane Rita, which made landfall 120 km to the west of WLD as a Category 3 storm in 2005, caused erosion on the right side and deposition on the left side of the hurricane eye track on the continental shelf line (water depth 10 m to 50 m. Erosion over a wide area occurred both on the continental shelf line and in coastal areas when the hurricane moved onshore, while deposition occurred along the Gulf coastline (water depth < 5 m when storm surge water moved back offshore. The numerical model estimated that Hurricane Rita’s storm surge reached 2.5 m, with maximum currents of 2.0 m s–1, and wave heights of 1.4 m on the WLD. The northwestern-directed flow and waves induced shear stresses, caused erosion on the eastern banks of the deltaic islands and deposition in channels located west of these islands. In total, Hurricane Rita eroded more than 500,000 m3 of sediments on the WLD area. Including waves in the analysis resulted in doubling the amount of erosion in the study area, comparing to the wave-excluding scenario. The exclusion of fluvial input caused minor changes in deltaic morphology during the event. Vegetation cover was represented as rigid rods in the model which add extra source terms for drag and turbulence to influence the momentum and turbulence equations. Vegetation slowed down the floodwater propagation and decreased flow velocity on the islands, leading to a 47% reduction in the total amount of erosion. Morphodynamic impact of the hurricane track relative to the delta was explored. Simulations indicate that the original track of Hurricane Rita (landfall 120 km west of the WLD produced twice as much erosion and deposition at the delta

  2. Orkaan Rita ähvardab rüüstata USA naftatööstuse südame / Annika Matson

    Index Scriptorium Estoniae

    Matson, Annika, 1976-

    2005-01-01

    Orkaan Rita läheneb USA naftatööstuse südamele Texasele, kus toodetakse veerand USA naftatoodetest. Diagramm: Naftafirmade aktsiate tõus. Vt. samas: Bensiini hinna olulist tõusu Eestis prognoosida oleks ennatlik

  3. Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu

    Directory of Open Access Journals (Sweden)

    Luan Jinwei

    2016-06-01

    Full Text Available Next generation sequencing and bio-informatic analyses were conducted to investigate the mechanism of reactivation of p53 and induction of tumor cell apoptosis (RITA-enhancing X-ray susceptibility in FaDu cells.

  4. The electronic Rothamsted Archive (e-RA), an online resource for data from the Rothamsted long-term experiments.

    Science.gov (United States)

    Perryman, Sarah A M; Castells-Brooke, Nathalie I D; Glendining, Margaret J; Goulding, Keith W T; Hawkesford, Malcolm J; Macdonald, Andy J; Ostler, Richard J; Poulton, Paul R; Rawlings, Christopher J; Scott, Tony; Verrier, Paul J

    2018-05-15

    The electronic Rothamsted Archive, e-RA (www.era.rothamsted.ac.uk) provides a permanent managed database to both securely store and disseminate data from Rothamsted Research's long-term field experiments (since 1843) and meteorological stations (since 1853). Both historical and contemporary data are made available via this online database which provides the scientific community with access to a unique continuous record of agricultural experiments and weather measured since the mid-19 th century. Qualitative information, such as treatment and management practices, plans and soil information, accompanies the data and are made available on the e-RA website. e-RA was released externally to the wider scientific community in 2013 and this paper describes its development, content, curation and the access process for data users. Case studies illustrate the diverse applications of the data, including its original intended purposes and recent unforeseen applications. Usage monitoring demonstrates the data are of increasing interest. Future developments, including adopting FAIR data principles, are proposed as the resource is increasingly recognised as a unique archive of data relevant to sustainable agriculture, agroecology and the environment.

  5. RITA enhances irradiation-induced apoptosis in p53-defective cervical cancer cells via upregulation of IRE1α/XBP1 signaling.

    Science.gov (United States)

    Zhu, Hong; Abulimiti, Muyasha; Liu, Huan; Su, Xiang-Jiang; Liu, Cai-Hong; Pei, Hai-Ping

    2015-09-01

    Radiation therapy is the most widely used treatment for patients with cervical cancer. Recent studies have shown that endoplasmic reticulum (ER) stress induces apoptosis and sensitizes tumor cells to radiotherapy, which reportedly induces ER stress in cells. Classical key tumor suppressor p53 is involved in the response to a variety of cellular stresses, including those incurred by ionizing irradiation. A recent study demonstrated that small-molecule RITA (reactivation of p53 and induction of tumor cell apoptosis) increased the radiosensitivity of tumor cells expressing mutant p53 (mtp53). In the present study, we explored the effects and the underlying mechanisms of RITA in regards to the radiosensitivity and ER stress in mtp53-expressing human cervix cancer cells. Treatment with 1 µM of RITA for 24 h before irradiation markedly decreased survival and increased apoptosis in C-33A and HT-3 cells; the effects were not significantly altered by knockdown of p53. In the irradiated C-33A and HT-3 cells, RITA significantly increased the expression of IRE1α, the spliced XBP1 mRNA level, as well as apoptosis; the effects were abolished by knockdown of IRE1α. Transcriptional pulse-chase assays revealed that RITA significantly increased the stability of IRE1α mRNA in the irradiated C-33A and HT-3 cells. In contrast, the same RITA treatment did not show any significant effect on sham-irradiated cells. In conclusion, the present study provides initial evidence that RITA upregulates the expression level of IRE1α by increasing the stability of IRE1α mRNA in irradiated mtp53-expressing cervical cancer cells; the effect leads to enhanced IRE1α/XBP1 ER stress signaling and increased apoptosis in the cells. The present study offers novel insight into the pharmacological potential of RITA in the radiotherapy for cervical cancer.

  6. Principles of formation of the content of an educational electronic resource on the basis of general and didactic patterns of learning

    Directory of Open Access Journals (Sweden)

    Ольга Юрьевна Заславская

    2018-12-01

    Full Text Available The article considers the influence of the development of technical means of teaching on the effectiveness of educational and methodical resources. Modern opportunities of information and communication technologies allow creating electronic educational resources that represent educational information that automates the learning process, provide information assistance, if necessary, collect and process statistical information on the degree of development of the content of the school material by schoolchildren, set an individual trajectory of learning, and so on. The main principle of data organization is the division of the training course into separate sections on the thematic elements and components of the learning process. General regularities include laws that encompass the entire didactic system, and in specific (particular cases, those whose actions extend to a separate component (aspect of the system. From the standpoint of the existence of three types of electronic training modules in the aggregate content of the electronic learning resource - information, control and module of practical classes - the principles of the formation of the electronic learning resource, in our opinion, should regulate all these components. Each of the certain principles is considered in the groups: scientific orientation, methodological orientation, systemic nature, accounting of interdisciplinary connections, fundamentalization, systematic and dosage sequence, rational use of study time, accessibility, minimization, operationalization of goals, unified identification diagnosis.

  7. The module of methodical support in system of electronic educational resources as the innovative element of the modern maintenance of formation

    Directory of Open Access Journals (Sweden)

    Ольга Николаевна Крылова

    2009-06-01

    Full Text Available The article introduces some results of research, which were devoted to evaluation of tearches' mobility to introduce innovations in the contents of education. The author considers innovative potential of modules of the methodical support for system of electronic educational resources.

  8. Charting a Course through CORAL: Texas A&M University Libraries' Experience Implementing an Open-Source Electronic Resources Management System

    Science.gov (United States)

    Hartnett, Eric; Beh, Eugenia; Resnick, Taryn; Ugaz, Ana; Tabacaru, Simona

    2013-01-01

    In 2010, after two previous unsuccessful attempts at electronic resources management system (ERMS) implementation, Texas A&M University (TAMU) Libraries set out once again to find an ERMS that would fit its needs. After surveying the field, TAMU Libraries selected the University of Notre Dame Hesburgh Libraries-developed, open-source ERMS,…

  9. Satellite Images and Aerial Photographs of the Effects of Hurricanes Katrina and Rita on Coastal Louisiana

    Science.gov (United States)

    Barras, John A.

    2007-01-01

    Introduction Hurricane Katrina made landfall on the eastern coastline of Louisiana on August 29, 2005; Hurricane Rita made landfall on the western coastline of Louisiana on September 24, 2005. Comparison of Landsat Thematic Mapper (TM) satellite imagery acquired before and after the landfalls of Katrina and Rita and classified to identify land and water demonstrated that water area increased by 217 mi2 (562 km2) in coastal Louisiana as a result of the storms. Approximately 82 mi2 (212 km2) of new water areas were in areas primarily impacted by Hurricane Katrina (Mississippi River Delta basin, Breton Sound basin, Pontchartrain basin, and Pearl River basin), whereas 99 mi2 (256 km2) were in areas primarily impacted by Hurricane Rita (Calcasieu/Sabine basin, Mermentau basin, Teche/Vermilion basin, Atchafalaya basin, and Terrebonne basin). Barataria basin contained new water areas caused by both hurricanes, resulting in some 18 mi2 (46.6 km2) of new water areas. The fresh marsh and intermediate marsh communities' land areas decreased by 122 mi2 (316 km2) and 90 mi2 (233.1 km2), respectively, and the brackish marsh and saline marsh communities' land areas decreased by 33 mi2 (85.5 km2) and 28 mi2 (72.5 km2), respectively. These new water areas represent land losses caused by direct removal of wetlands. They also indicate transitory changes in water area caused by remnant flooding, removal of aquatic vegetation, scouring of marsh vegetation, and water-level variation attributed to normal tidal and meteorological variation between satellite images. Permanent losses cannot be estimated until several growing seasons have passed and the transitory impacts of the hurricanes are minimized. The purpose of this study was to provide preliminary information on water area changes in coastal Louisiana acquired shortly after the landfalls of both hurricanes (detectable with Landsat TM imagery) and to serve as a regional baseline for monitoring posthurricane wetland recovery. The land

  10. The monochromatic imaging mode of a RITA-type neutron spectrometer

    International Nuclear Information System (INIS)

    Bahl, C.R.H.; Andersen, P.; Klausen, S.N.; Lefmann, K.

    2004-01-01

    The imaging monochromatic mode of a neutron spectrometer with a multi-bladed RITA analyser system is so far unexplored. We present analytical calculations that define the mode. It is shown that the mode can be realised for PG (0 0 2) analyser crystals, from incident energies of about 3.2 meV and up, allowing the important cases of 3.7, 5.0 and 13.7 meV. Due to beam divergence, the neutron rays from neighbouring analyser blades are found to overlap slightly. Hence, the optimal use of the monochromatic imaging mode would be found by employing an adjustable radial collimator to limit the spread of the ray from each analyser blade

  11. Bacteriological water quality in the Lake Pontchartrain basin Louisiana following Hurricanes Katrina and Rita, September 2005

    Science.gov (United States)

    Stoeckel, Donald M.; Bushon, Rebecca N.; Demcheck, Dennis K.; Skrobialowski, Stanley C.; Kephart, Christopher M.; Bertke, Erin E.; Mailot, Brian E.; Mize, Scott V.; Fendick, Robert B.

    2005-01-01

    The U.S. Geological Survey (USGS), in collaboration with the Louisiana Department of Environmental Quality, monitored bacteriological quality of water at 22 sites in and around Lake Pontchartrain, La., for three consecutive weeks beginning September 13, 2005, following hurricanes Katrina and Rita and the associated flooding. Samples were collected and analyzed by USGS personnel from the USGS Louisiana Water Science Center and the USGS Ohio Water Microbiology Laboratory. Fecal-indicator bacteria (Escherichia coli, enterococci, and fecal coliform) concentrations ranged from the detection limit to 36,000 colony-forming units per 100 milliliters. Data are presented in tabular form and as plots of data in the context of available historical data and water-quality standards and criteria for each site sampled. Quality-control data were reviewed to ensure that methods performed as expected in a mobile laboratory setting.

  12. Rita Temmerman. Towards New Ways of Terminology Description: The Sociocognitive Approach

    Directory of Open Access Journals (Sweden)

    Rosemarie Gläser

    2011-10-01

    Full Text Available This book appeared as Volume 3 in the Series Terminology and Lexicography Research and Practice edited by Helmi Sonneveld and Sue-Ellen Wright. The author, Rita Temmerman, presently working at the Erasmus Hogeschool, Brussels and specialising in problems of terminology in various domains of the life sciences, presents a polemical, stimulating and innovative monograph which continues and deepens her previous research work. Her doctoral dissertation (Louvain 1998 focused on Terminology Beyond Standardisation: Language and Categorisation in the Life Sciences. The aim of the book under review, Towards New Ways of Terminology Description: The Sociocognitive Approach, is to elaborate a new theory, method and application of terminology research which seeks to overcome the obvious limitations of traditional terminology as chiefly represented by the Vienna School (Eugen W?ster, Helmut Felber, Infoterm and associated institutions.

  13. Rezension zu: Rita Pawlowski (Hg.: „Unsere Frauen stehen ihren Mann“. Berlin: trafo Wissenschaftsverlag 2008

    Directory of Open Access Journals (Sweden)

    Susanne Freund

    2009-07-01

    Full Text Available Rita Pawlowski stellt in diesem Band in alphabethischer Ordnung insgesamt 651 Frauen vor, die Abgeordnete der Volkskammer der DDR waren. Nach einer knappen Einführung zur Wahlhäufigkeit weiblicher Abgeordneter, zum Frauenanteil in der Volkskammer und in den Ausschüssen geben die Biographen im Wesentlichen Auskunft über die soziale Herkunft, die Parteizugehörigkeit, die schulische und berufliche Ausbildung und die Berufstätigkeit der einzelnen Frauen. Ziel dieses Bandes ist die Dokumentation des außergewöhnlichen Engagements von Frauen in der DDR, neben Berufstätigkeit und Familienpflichten politische Einflussmöglichkeiten zu nutzen. Damit wird ein Teilaspekt der Lebensgeschichte dieser Frauen beleuchtet, der – wie die Autorin im Vorfeld einräumt – keinen Anspruch auf Vollständigkeit erhebt. Dieser Hinweis ist wichtig, um dieses lexikalische Nachschlagewerk sinnvoll zu handhaben.

  14. The monochromatic imaging mode of a RITA-type neutron spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Bahl, C.R.H. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark) and Department of Physics, Technical University of Denmark, DK-2800 Lyngby (Denmark)]. E-mail: christian.bahl@risoe.dk; Andersen, P. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Niels Bohr Institute for Astronomy, Physics and Geophysics, University of Copenhagen, DK-2100 Copenhagen (Denmark); Klausen, S.N. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Lefmann, K. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark)

    2004-12-01

    The imaging monochromatic mode of a neutron spectrometer with a multi-bladed RITA analyser system is so far unexplored. We present analytical calculations that define the mode. It is shown that the mode can be realised for PG (0 0 2) analyser crystals, from incident energies of about 3.2 meV and up, allowing the important cases of 3.7, 5.0 and 13.7 meV. Due to beam divergence, the neutron rays from neighbouring analyser blades are found to overlap slightly. Hence, the optimal use of the monochromatic imaging mode would be found by employing an adjustable radial collimator to limit the spread of the ray from each analyser blade.

  15. Efficient synthesis of RITA and its analogues: derivation of analogues with improved antiproliferative activity via modulation of p53/miR-34a pathway.

    Science.gov (United States)

    Lin, Jinshun; Jin, Xiuli; Bu, Yiwen; Cao, Deliang; Zhang, Nannan; Li, Shangfu; Sun, Qinsheng; Tan, Chunyan; Gao, Chunmei; Jiang, Yuyang

    2012-12-28

    A novel approach to synthesize RITA by practical palladium-catalyzed C-C bond-forming Suzuki reactions at room temperature was developed, which was used for deriving a series of substituted tricyclic α-heteroaryl (furan/thiophene) analogues of RITA under mild conditions. These novel analogues showed notable antiproliferative activity against cancer cell lines with wild-type p53 (i.e., HCT116, A549, MCF-7 and K562), but much less activity in HCT116/p53(-/-) cells. In particular, compound 1f demonstrated promising antiproliferative activity compared to RITA, with IC(50) = 28 nM in MCF-7 vs. 54 nM for RITA, and cancer cell selectivity. Compound 1f markedly activated p53 in HCT116 cells at 100 nM, triggering apoptosis. Importantly, we found that both RITA and compound 1f induced G(0)/G(1) cell cycle arrest by up-regulating miR-34a, which in turn down-regulated the expression of cell cycle-related proteins CDK4 and E2F1. In summary, this study reports an effective synthetic approach for RITA and its analogues, and elucidates a novel antiproliferative mechanism of these compounds.

  16. Initial management of hospital evacuations caused by Hurricane Rita: a systematic investigation.

    Science.gov (United States)

    Downey, Erin L; Andress, Knox; Schultz, Carl H

    2013-06-01

    Hurricanes remain a major threat to hospitals throughout the world. The authors attempted to identify the planning areas that impact hospital management of evacuations and the challenges faced when sheltering-in-place. This observational, retrospective cohort study examined acute care institutions from one hospital system impacted by Hurricane Rita in 2005. Investigators used a standardized survey instrument and interview process, previously used in the hospital evacuation context, to examine hospitals' initial internal situational awareness and subsequent decision making that resulted in evacuation due to Hurricane Rita. Participants from each hospital included representatives from senior leadership and clinical and nonclinical staff that comprised the Incident Management Team (IMT). The main measured outcomes were responses to 95 questions contained in the survey. Seven of ten eligible hospitals participated in the study. All facilities evacuated the sickest patients first. The most significant factors prompting evacuation were the issuing of mandatory evacuation orders, storm dynamics (category, projected path, storm surge), and loss of regional communications. Hospitals that sheltered-in-place experienced staff shortages, interruptions to electrical power, and loss of water supplies. Three fully-evacuated institutions experienced understaffing of 40%-60%, and four hospitals sustained depressed staffing levels for over four weeks. Five hospitals lost electricity for a mean of 4.8 days (range .5-11 days). All facilities continued to receive patients to their Emergency Departments (EDs) while conducting their own evacuation. Hospital EDs should plan for continuous patient arrival during evacuation. Emergency Operation Plans (EOPs) that anticipate challenges associated with evacuation will help to maximize initial decision making and management during a crisis situation. Hospitals that shelter-in-place face critical shortages and must provide independent patient

  17. Mapping and Visualization of Storm-Surge Dynamics for Hurricane Katrina and Hurricane Rita

    Science.gov (United States)

    Gesch, Dean B.

    2009-01-01

    The damages caused by the storm surges from Hurricane Katrina and Hurricane Rita were significant and occurred over broad areas. Storm-surge maps are among the most useful geospatial datasets for hurricane recovery, impact assessments, and mitigation planning for future storms. Surveyed high-water marks were used to generate a maximum storm-surge surface for Hurricane Katrina extending from eastern Louisiana to Mobile Bay, Alabama. The interpolated surface was intersected with high-resolution lidar elevation data covering the study area to produce a highly detailed digital storm-surge inundation map. The storm-surge dataset and related data are available for display and query in a Web-based viewer application. A unique water-level dataset from a network of portable pressure sensors deployed in the days just prior to Hurricane Rita's landfall captured the hurricane's storm surge. The recorded sensor data provided water-level measurements with a very high temporal resolution at surveyed point locations. The resulting dataset was used to generate a time series of storm-surge surfaces that documents the surge dynamics in a new, spatially explicit way. The temporal information contained in the multiple storm-surge surfaces can be visualized in a number of ways to portray how the surge interacted with and was affected by land surface features. Spatially explicit storm-surge products can be useful for a variety of hurricane impact assessments, especially studies of wetland and land changes where knowledge of the extent and magnitude of storm-surge flooding is critical.

  18. Rita Pawlowski (Hg.: „Unsere Frauen stehen ihren Mann“. Berlin: trafo Wissenschaftsverlag 2008

    Directory of Open Access Journals (Sweden)

    Susanne Freund

    2009-07-01

    Full Text Available Rita Pawlowski stellt in diesem Band in alphabethischer Ordnung insgesamt 651 Frauen vor, die Abgeordnete der Volkskammer der DDR waren. Nach einer knappen Einführung zur Wahlhäufigkeit weiblicher Abgeordneter, zum Frauenanteil in der Volkskammer und in den Ausschüssen geben die Biographen im Wesentlichen Auskunft über die soziale Herkunft, die Parteizugehörigkeit, die schulische und berufliche Ausbildung und die Berufstätigkeit der einzelnen Frauen. Ziel dieses Bandes ist die Dokumentation des außergewöhnlichen Engagements von Frauen in der DDR, neben Berufstätigkeit und Familienpflichten politische Einflussmöglichkeiten zu nutzen. Damit wird ein Teilaspekt der Lebensgeschichte dieser Frauen beleuchtet, der – wie die Autorin im Vorfeld einräumt – keinen Anspruch auf Vollständigkeit erhebt. Dieser Hinweis ist wichtig, um dieses lexikalische Nachschlagewerk sinnvoll zu handhaben.In this volume, Rita Pawlowski alphabetically introduces a total of 651 women who were representatives of the People’s Chamber of the GDR. Following a short introduction to the election frequency of female representatives and to the number of women in the People’s Chamber and its committees, the biographies provide information on the social origin, party membership, educational and occupational training, and professional life of the individual women. The volume’s goal is to document these women’s extraordinary engagement in the GDR, for they not only held careers and fulfilled family duties, but also pursued possibilities for making political impact. The authors note at the outset that the book does not claim to be comprehensive, for it illuminates merely one aspect of the life stories of these women. This remark is important for making the reference work manageable.

  19. Land area change and fractional water maps in the Chenier Plain, Louisiana, following hurricane Rita

    Science.gov (United States)

    Palaseanu-Lovejoy, M.; Kranenburg, C.; Brock, J. C.

    2009-12-01

    The objective of this study is to develop a fractional water map at 30-m resolution scale using QuickBird and/or IKONOS high-resolution imagery as dependent variable to investigate the impact of hurricane Rita in the Chenier Plain, Louisiana. Eleven different indices were tested to obtain a high-resolution land / water classification on QuickBird (acquired on 05/23/2003) and IKONOS (acquired on 03/25/2006) images. The percent area covered by water in the high resolution images varied from 22 to 26% depending on the index used , with the simple ratio index (red band / NIR band) accounting for the lowest percent and the blue ratio index (blue band / sum(all bands)) for the highest percent. Using the ERDAS NLCD (National Land Cover Data) Mapping tool module, 100, 000 stratified random sample points with minimum 1000 points per stratum were selected from the high resolution dependent variable as training information for the independent variable layers. The rules for the regression tree were created using the data mining software Rulequest Cubist v. 2.05. This information was used to generate a fractional water map for the entire Landsat scene. The increase in water areas of about 10 - 15% between 2003 to 2006, as well as temporary changes in the water - land configurations are attributed to remnant flooding and removal of aquatic vegetation caused by hurricane Rita, and water level variations caused by tidal and / or meteorological variations between the acquisition dates of the satellite images. This analysis can assist in monitoring post-hurricane wetland recovery and assess trends in land loss due to extreme storm events, although estimation of permanent land loss cannot be made until wetland areas have the opportunity to recover from hurricane impacts.

  20. O Centro Espírita Redemptor e o tratamento de doença mental, 1910-1921 The Centro Espírita Redemptor and the treatment of mental illness, 1910-1921

    Directory of Open Access Journals (Sweden)

    André de Faria Pereira Neto

    2012-06-01

    Full Text Available O espiritismo é uma doutrina religiosa que surgiu na França durante o século XIX por meio da obra de Allan Kardec. No Brasil, assumiu certa originalidade: o espiritismo racional e científico cristão, liderado por Luiz de Mattos, foi uma de suas vertentes doutrinárias nacionais. Luiz de Mattos criou o Centro Espírita Redemptor onde, durante alguns anos, acompanhou o tratamento dos doentes mentais. O artigo analisa as características do tratamento espírita racional e científico cristão à doença mental e as estratégias que Luiz de Mattos adotou para defender sua forma de tratamento. Apresenta ainda algumas semelhanças e diferenças entre o tratamento espírita e o médico.Spiritism is a religious doctrine originated in France during the nineteenth century through the works of Allan Kardec. In Brazil, it assumed an original configuration: rational and scientific Christian spiritism, pioneered by Luiz de Mattos, was one of the national doctrinal variants. Luiz de Mattos created the Centro Espírita Redemptor where, for some years, he monitored the treatment of the mentally ill. The article analyzes the characteristics of rational and scientific Christian spiritism treatment applied to mental illness and the strategies that Luiz de Mattos adopted to defend his form of treatment. Some similarities and differences between spiritist and medical treatment are also outlined.

  1. A Kiss Lajos-díj 2016. évi nyertese: dr. Póczos Rita [Winner of the 2016 Lajos Kiss Prize: Dr Rita Póczos

    Directory of Open Access Journals (Sweden)

    Hoffmann, István

    2016-12-01

    Full Text Available The Lajos Kiss Prize, awarded every two or three years since 2006, is considered to be a highly prestigious award for young onomasticians. The 2016 winner of the prize is Dr Rita Póczos, senior lecturer at the Department of Hungarian Linguistics of the University of Debrecen. She was given this award for her contribution to Hungarian Historical Onomastics, especially for her research on place names.

  2. Electronics

    Science.gov (United States)

    2001-01-01

    International Acer Incorporated, Hsin Chu, Taiwan Aerospace Industrial Development Corporation, Taichung, Taiwan American Institute of Taiwan, Taipei, Taiwan...Singapore and Malaysia .5 - 4 - The largest market for semiconductor products is the high technology consumer electronics industry that consumes up...Singapore, and Malaysia . A new semiconductor facility costs around $3 billion to build and takes about two years to become operational

  3. UPANJE IN SVOBODA V DELU STEPHENA KINGA RITA HAYWORTH AND SHAWSHANK REDEMPTION IN ALEXANDRE DUMAS GROF MONTE CRISTO

    OpenAIRE

    Kramar, Vesna

    2011-01-01

    Rita Hayworth and Shawshank Redemption Stephena Kinga in Grof Monte Cristo Alexandra Dumasa izhajata iz različnih literarnih žanrov in se razlikujeta v dogajanju, a imata kljub temu podobno motiviko in tematiko. V obeh zgodbah je nedolžen mož poslan v zapor, iz katerega je pobeg skorajda nemogoč, a se kljub temu obema uspe izmuzniti iz zapora na podoben način

  4. Satellite Assessment of Bio-Optical Properties of Northern Gulf of Mexico Coastal Waters Following Hurricanes Katrina and Rita

    OpenAIRE

    Lohrenz, Steven E.; Cai, Wei-Jun; Chen, Xiaogang; Tuel, Merritt

    2008-01-01

    The impacts of major tropical storms events on coastal waters include sediment resuspension, intense water column mixing, and increased delivery of terrestrial materials into coastal waters. We examined satellite imagery acquired by the Moderate Resolution Imaging Spectroradiometer (MODIS) ocean color sensor aboard the Aqua spacecraft following two major hurricane events: Hurricane Katrina, which made landfall on 29 August 2005, and Hurricane Rita, which made landfall on 24 September. MODIS A...

  5. Spatial-temporal water quality parameters evaluation of the Santa Rita river (BA with respect to the release of manipueira

    Directory of Open Access Journals (Sweden)

    Franklin Delano Porto Júnior

    2012-12-01

    Full Text Available The watershed of the river Santa Rita includes the towns of Simão and Campinhos, where exists about 150 flour houses. Campinhos is among the largest cassava processing facilities in the region, generating many direct and indirect jobs. Manipueira is a liquid residue originating from the cassava pressing and presents high pollutant potential due to its high amount of glucose and fructose, this potential is 25 times greater than the one from domestic sewer. This work had as objective the evaluation of possible impacts of manipueira release in the water quality of Santa Rita river. For this, the land use map was elaborated and the physiographic characterization developed, besides being performed six campaigns for water samples collection in four sampling points along the river. The obtained results indicated that the watershed is elongated, with low drainage efficiency and it is not prone to flooding. Estimated water quality parameters indicated that organic effluents from Campinhos and Simão impact the values of dissolved oxygen, electrical conductivity, salinity, ammonia, nitrite, nitrate and zinc, suggesting that the water quality of the river Santa Rita is affected by manipueira release. The concentrations of total phosphorus, iron and cooper were superior downstream of the Sewer Treatment Station. The river water was saline in the three sampling points most affected by the release of manipueira.

  6. Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu).

    Science.gov (United States)

    Luan, Jinwei; Li, Xianglan; Guo, Rutao; Liu, Shanshan; Luo, Hongyu; You, Qingshan

    2016-06-01

    Next generation sequencing and bio-informatic analyses were conducted to investigate the mechanism of reactivation of p53 and induction of tumor cell apoptosis (RITA)-enhancing X-ray susceptibility in FaDu cells. The cDNA was isolated from FaDu cells treated with 0 X-ray, 8 Gy X-ray, or 8 Gy X-ray + RITA. Then, cDNA libraries were created and sequenced using next generation sequencing, and each assay was repeated twice. Subsequently, differentially expressed genes (DEGs) were identified using Cuffdiff in Cufflinks and their functions were predicted by pathway enrichment analyses. Genes that were constantly up- or down-regulated in 8 Gy X-ray-treated FaDu cells and 8 Gy X-ray + RITA-treated FaDu cells were obtained as RITA genes. Afterward, the protein-protein interaction (PPI) relationships were obtained from the STRING database and a PPI network was constructed using Cytoscape. Furthermore, ClueGO was used for pathway enrichment analysis of genes in the PPI network. Total 2,040 and 297 DEGs were identified in FaDu cells treated with 8 Gy X-ray or 8 Gy X-ray + RITA, respectively. PARP3 and NEIL1 were enriched in base excision repair, and CDK1 was enriched in p53 signaling pathway. RFC2 and EZH2 were identified as RITA genes. In the PPI network, many interaction relationships were identified (e.g., RFC2-CDK1, EZH2-CDK1 and PARP3-EZH2). ClueGO analysis showed that RFC2 and EZH2 were related to cell cycle. RFC2, EZH2, CDK1, PARP3 and NEIL1 may be associated, and together enhance the susceptibility of FaDu cells treated with RITA to the deleterious effects of X-ray.

  7. Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu)

    International Nuclear Information System (INIS)

    Luan, Jinwei; Li, Xianglan; Guo, Rutao; Liu, Shanshan; Luo, Hongyu; You, Qingshan

    2016-01-01

    Next generation sequencing and bio-informatic analyses were conducted to investigate the mechanism of reactivation of p53 and induction of tumor cell apoptosis (RITA)-enhancing X-ray susceptibility in FaDu cells. The cDNA was isolated from FaDu cells treated with 0 X-ray, 8 Gy X-ray, or 8 Gy X-ray + RITA. Then, cDNA libraries were created and sequenced using next generation sequencing, and each assay was repeated twice. Subsequently, differentially expressed genes (DEGs) were identified using Cuffdiff in Cufflinks and their functions were predicted by pathway enrichment analyses. Genes that were constantly up- or down-regulated in 8 Gy X-ray-treated FaDu cells and 8 Gy X-ray + RITA-treated FaDu cells were obtained as RITA genes. Afterward, the protein-protein interaction (PPI) relationships were obtained from the STRING database and a PPI network was constructed using Cytoscape. Furthermore, ClueGO was used for pathway enrichment analysis of genes in the PPI network. Total 2,040 and 297 DEGs were identified in FaDu cells treated with 8 Gy X-ray or 8 Gy X-ray + RITA, respectively. PARP3 and NEIL1 were enriched in base excision repair, and CDK1 was enriched in p53 signaling pathway. RFC2 and EZH2 were identified as RITA genes. In the PPI network, many interaction relationships were identified (e.g., RFC2-CDK1, EZH2-CDK1 and PARP3-EZH2). ClueGO analysis showed that RFC2 and EZH2 were related to cell cycle. RFC2, EZH2, CDK1, PARP3 and NEIL1 may be associated, and together enhance the susceptibility of FaDu cells treated with RITA to the deleterious effects of X-ray

  8. Evaluation of three electronic report processing systems for preparing hydrologic reports of the U.S Geological Survey, Water Resources Division

    Science.gov (United States)

    Stiltner, G.J.

    1990-01-01

    In 1987, the Water Resources Division of the U.S. Geological Survey undertook three pilot projects to evaluate electronic report processing systems as a means to improve the quality and timeliness of reports pertaining to water resources investigations. The three projects selected for study included the use of the following configuration of software and hardware: Ventura Publisher software on an IBM model AT personal computer, PageMaker software on a Macintosh computer, and FrameMaker software on a Sun Microsystems workstation. The following assessment criteria were to be addressed in the pilot studies: The combined use of text, tables, and graphics; analysis of time; ease of learning; compatibility with the existing minicomputer system; and technical limitations. It was considered essential that the camera-ready copy produced be in a format suitable for publication. Visual improvement alone was not a consideration. This report consolidates and summarizes the findings of the electronic report processing pilot projects. Text and table files originating on the existing minicomputer system were successfully transformed to the electronic report processing systems in American Standard Code for Information Interchange (ASCII) format. Graphics prepared using a proprietary graphics software package were transferred to all the electronic report processing software through the use of Computer Graphic Metafiles. Graphics from other sources were entered into the systems by scanning paper images. Comparative analysis of time needed to process text and tables by the electronic report processing systems and by conventional methods indicated that, although more time is invested in creating the original page composition for an electronically processed report , substantial time is saved in producing subsequent reports because the format can be stored and re-used by electronic means as a template. Because of the more compact page layouts, costs of printing the reports were 15% to 25

  9. Electronic resources of the rare books and valuable editions department of the Central Scientific Library of the V.N. Karazin Kharkiv National University: open access for research

    Directory of Open Access Journals (Sweden)

    І. К. Журавльова

    2014-12-01

    Full Text Available The article describes tasks that electronic collections of rare books fulfill: broad access for readers to rare and valuable editions providing, preservation of ensuring of the original. On the example of the electronic collection of the Central Scientific Library of the V.N. Karazin Kharkiv National University – «eScriptorium: electronic archive of rare books and manuscripts for research and education» the possibility of the full-text resources of the valuable editions using is shown. The principles of creation, structure, chronological frameworks, directions of adding the documents to the archive are represented. The perspectives of the project development are outlined as well as examples of the digital libraries of the European countries and Ukraine are provided, the actual task of preserving the originals of the rare books of the country is raised, the innovative approaches to serving users with electronic resources are considered. The evidences of cooperation of the Central Scientific Library of the V.N. Karazin Kharkiv National University with the largest world digital libraries: World Digital Library and Europeana are provided.

  10. The use of quality benchmarking in assessing web resources for the dermatology virtual branch library of the National electronic Library for Health (NeLH).

    Science.gov (United States)

    Kamel Boulos, M N; Roudsari, A V; Gordon, C; Muir Gray, J A

    2001-01-01

    In 1998, the U.K. National Health Service Information for Health Strategy proposed the implementation of a National electronic Library for Health to provide clinicians, healthcare managers and planners, patients and the public with easy, round the clock access to high quality, up-to-date electronic information on health and healthcare. The Virtual Branch Libraries are among the most important components of the National electronic Library for Health. They aim at creating online knowledge based communities, each concerned with some specific clinical and other health-related topics. This study is about the envisaged Dermatology Virtual Branch Libraries of the National electronic Library for Health. It aims at selecting suitable dermatology Web resources for inclusion in the forthcoming Virtual Branch Libraries after establishing preliminary quality benchmarking rules for this task. Psoriasis, being a common dermatological condition, has been chosen as a starting point. Because quality is a principal concern of the National electronic Library for Health, the study includes a review of the major quality benchmarking systems available today for assessing health-related Web sites. The methodology of developing a quality benchmarking system has been also reviewed. Aided by metasearch Web tools, candidate resources were hand-selected in light of the reviewed benchmarking systems and specific criteria set by the authors. Over 90 professional and patient-oriented Web resources on psoriasis and dermatology in general are suggested for inclusion in the forthcoming Dermatology Virtual Branch Libraries. The idea of an all-in knowledge-hallmarking instrument for the National electronic Library for Health is also proposed based on the reviewed quality benchmarking systems. Skilled, methodical, organized human reviewing, selection and filtering based on well-defined quality appraisal criteria seems likely to be the key ingredient in the envisaged National electronic Library for

  11. Barriers to electronic access and delivery of educational information in resource constrained public schools: a case of Greater Tubatse Municipality

    CSIR Research Space (South Africa)

    Pholotho, T

    2016-05-01

    Full Text Available Information and Communication Technologies (ICTs) are capable of expanding access to quality education, educational resources and provide teachers with new skills. Nevertheless, a majority of rural public schools have limited ICTs, mainly due...

  12. Electronic Grey Literature in Accelerator Science and Its Allied Subjects : Selected Web Resources for Scientists and Engineers

    CERN Document Server

    Rajendiran, P

    2006-01-01

    Grey literature Web resources in the field of accelerator science and its allied subjects are collected for the scientists and engineers of RRCAT (Raja Ramanna Centre for Advanced Technology). For definition purposes the different types of grey literature are described. The Web resources collected and compiled in this article (with an overview and link for each) specifically focus on technical reports, preprints or e-prints, which meet the main information needs of RRCAT users.

  13. Use of Temporary Immersion System (RITA in sugarcane the plants propagation by organogenesis

    Directory of Open Access Journals (Sweden)

    Laisyn Posada-Pérez

    2003-01-01

    Full Text Available The present work had as objective to study the possibilities to use the RITA, in the micropropagation plant via axillary buds of sugarcane and of the banana hybrid (Musa sp. AAAA cv. FHIA-01 and AAAB cv. FHIA-18. Two different culture medium i.e. multiplication and thickenment were studied in the multiplication phase of two varieties of sugarcane. It was also studied the number of initial explants to use (two, four and six, using as control flasks with explants liquid and semisolid medium. The number of immersions in 24 hours was analysed and also the time for culture media change was determined testing two periods, 15 days and 30 days respectively. Similar variables were studied for the case of the banana cultivar except for the medium culture. It was obtained like half of more appropriate cultivation for sugarcane that of multiplication with two explants, in the two used varieties, not presenting significant differences the times of change of half made to the 15 and 30 days. For the case of the banana cultivar employment of five explantes for FHIA-01 and three or five explantes for FHIA-18 to begin the multiplication allowed to reach the best results. Regarding the number of immersions it presented bigger superiority the treatment of three immersions during 24 hours, for both banana cultivars. Keys words: liquid medium, micropropagation, Musa, Saccharum

  14. Hazardous substances releases associated with Hurricanes Katrina and Rita in industrial settings, Louisiana and Texas.

    Science.gov (United States)

    Ruckart, Perri Zeitz; Orr, Maureen F; Lanier, Kenneth; Koehler, Allison

    2008-11-15

    The scientific literature concerning the public health response to the unprecedented hurricanes striking the Gulf Coast in August and September 2005 has focused mainly on assessing health-related needs and surveillance of injuries, infectious diseases, and other illnesses. However, the hurricanes also resulted in unintended hazardous substances releases in the affected states. Data from two states (Louisiana and Texas) participating in the Hazardous Substances Emergency Events Surveillance (HSEES) system were analyzed to describe the characteristics of hazardous substances releases in industrial settings associated with Hurricanes Katrina and Rita. HSEES is an active multi-state Web-based surveillance system maintained by the Agency for Toxic Substances and Disease Registry (ATSDR). In 2005, 166 hurricane-related hazardous substances events in industrial settings in Louisiana and Texas were reported. Most (72.3%) releases were due to emergency shut downs in preparation for the hurricanes and start-ups after the hurricanes. Emphasis is given to the contributing causal factors, hazardous substances released, and event scenarios. Recommendations are made to prevent or minimize acute releases of hazardous substances during future hurricanes, including installing backup power generation, securing equipment and piping to withstand high winds, establishing procedures to shutdown process operations safely, following established and up-to-date start-up procedures and checklists, and carefully performing pre-start-up safety reviews.

  15. Changes in microbial community structure in the wake of Hurricanes Katrina and Rita.

    Science.gov (United States)

    Amaral-Zettler, Linda A; Rocca, Jennifer D; Lamontagne, Michael G; Dennett, Mark R; Gast, Rebecca J

    2008-12-15

    Hurricanes have the potential to alter the structures of coastal ecosystems and generate pathogen-laden floodwaters thatthreaten public health. To examine the impact of hurricanes on urban systems, we compared microbial community structures in samples collected after Hurricane Katrina and before and after Hurricane Rita. We extracted environmental DNA and sequenced small-subunit rRNA (SSU rRNA) gene clone libraries to survey microbial communities in floodwater, water, and sediment samples collected from Lake Charles, Lake Pontchartrain, the 17th Street and Industrial Canals in New Orleans, and raw sewage. Correspondence analysis showed that microbial communities associated with sediments formed one cluster while communities associated with lake and Industrial Canal water formed a second. Communities associated with water from the 17th Street Canal and floodwaters collected in New Orleans showed similarity to communities in raw sewage and contained a number of sequences associated with possible pathogenic microbes. This suggests that a distinct microbial community developed in floodwaters following Hurricane Katrina and that microbial community structures as a whole might be sensitive indicators of ecosystem health and serve as "sentinels" of water quality in the environment.

  16. Somatic experiencing treatment with social service workers following Hurricanes Katrina and Rita.

    Science.gov (United States)

    Leitch, M Laurie; Vanslyke, Jan; Allen, Marisa

    2009-01-01

    In a disaster, social service workers are often survivors themselves.This study examines whether somatic intervention using a brief (one to two session) stabilization model now called the Trauma Resiliency Model (TRM), which uses the skills of Somatic Experiencing (SE), can reduce the postdisaster symptoms of social service workers involved in postdisaster service delivery.The study was implemented with a nonrandom sample of 142 social service workers who were survivors of Hurricanes Katrina and Rita in New Orleans and Baton Rouge, Louisiana, two to three months after the disasters. Ninety-one participants received SE/TRM and were compared with a matched comparison group of 51 participants through the use of propensity score matching. All participants first received group psychoeducation. Results support the benefits of the brief intervention inspired by SE. The treatment group showed statistically significant gains in resiliency indicators and decreases in posttraumatic stress disorder symptoms. Although psychological symptoms increased in both groups at the three to four month follow-up, the treatment group's psychological symptoms were statistically lower than those of the comparison group.

  17. Lead distributions and risks in New Orleans following Hurricanes Katrina and Rita.

    Science.gov (United States)

    Abel, Michael T; Cobb, George P; Presley, Steven M; Ray, Gary L; Rainwater, Thomas R; Austin, Galen P; Cox, Stephen B; Anderson, Todd A; Leftwich, Blair D; Kendall, Ronald J; Suedel, Burton C

    2010-07-01

    During the last four years, significant effort has been devoted to understanding the effects that Hurricanes Katrina and Rita had on contaminant distribution and redistribution in New Orleans, Louisiana, USA, and the surrounding Gulf Coast area. Elevated concentrations were found for inorganic contaminants (including As, Fe, Pb, and V), several organic pollutants (polycyclic aromatic hydrocarbons, pesticides, and volatiles) and high concentration of bioaerosols, particularly Aeromonas and Vibrio. Data from different research groups confirm that some contaminant concentrations are elevated, that existing concentrations are similar to historical data, and that contaminants such as Pb and As may pose human health risks. Two data sets have been compiled in this article to serve as the foundation for preliminary risk assessments within greater New Orleans. Research from the present study suggests that children in highly contaminated areas of New Orleans may experience Pb exposure from soil ranging from 1.37 microg/d to 102 microg/d. These data are critical in the evaluation of children's health. Copyright (c) 2010 SETAC.

  18. The effects of hurricane Rita and subsequent drought on alligators in southwest Louisiana.

    Science.gov (United States)

    Lance, Valentine A; Elsey, Ruth M; Butterstein, George; Trosclair, Phillip L; Merchant, Mark

    2010-02-01

    Hurricane Rita struck the coast of southwest Louisiana in September 2005. The storm generated an enormous tidal surge of approximately four meters in height that inundated many thousands of acres of the coastal marsh with full strength seawater. The initial surge resulted in the deaths of a number of alligators and severely stressed those who survived. In addition, a prolonged drought (the lowest rainfall in 111 years of recorded weather data) following the hurricane resulted in highly saline conditions that persisted in the marsh for several months. We had the opportunity to collect 11 blood samples from alligators located on Holly Beach less than a month after the hurricane, but were unable to collect samples from alligators on Rockefeller Wildlife Refuge until February 2006. Conditions at Rockefeller Refuge did not permit systematic sampling, but a total of 201 samples were collected on the refuge up through August 2006. The blood samples were analyzed for sodium, potassium, chloride, osmolality, and corticosterone. Blood samples from alligators sampled on Holly Beach in October 2005, showed a marked elevation in plasma osmolality, sodium, chloride, potassium, corticosterone, and an elevated heterophil/lymphocyte ratio. Blood samples from alligators on Rockefeller Refuge showed increasing levels of corticosterone as the drought persisted and elevated osmolality and electrolytes. After substantial rainfall in July and August, these indices of osmotic stress returned to within normal limits. (c) 2009 Wiley-Liss, Inc.

  19. Ethnobotanical study of medicinal plants in the community of Santa Rita, Ituiutaba – Minas Gerais, Brazil

    Directory of Open Access Journals (Sweden)

    Glaucieli Siqueira Parreira Alves

    2013-09-01

    Full Text Available This paper aimed to inventory the plants used in popular medicine by members of the rural community of Santa Rita, in the town of Ituiutaba, Minas Gerais, Brazil. The evaluation was carried out through interviews, with a semi-structured questionnaire and subsequent collection of the plants indicated by informants. One conducted 47 interviews and 127 species were listed, belonging to 55 Angiosperm families. For obtaining the quantitative data, one calculated the percentage of the Main Use Concordance (cMUC of each species; for identifying the therapeutic indications with greater importance, one used the Informant Consensus Factor (ICF. The cMUC showed that 5.5% of the plants mentioned are widely used by the community. The predominant botanical families registered were Lamiaceae and Asteraceae, with 14 and 13 records, respectively. The indication of predominant use mainly involved illnesses related to an emotional disorder, as indicated by the ICF. One emphasizes that 60.7% of the plants mentioned in this paper are exotic species; thus, there’s a need for further studies in order to catalogue knowledge on the medicinal plants which are native to this region.

  20. The Multiple Life of Nerve Growth Factor: Tribute to Rita Levi-Montalcini (1909-2012

    Directory of Open Access Journals (Sweden)

    Luigi Aloe

    2013-03-01

    Full Text Available At the end of the 19th century, it was envisaged by Santiago Ramon y Cajal, but not, proven, that life at the neuronal level requires trophic support. The proof was obtained in the early 1950's by work initiated by Rita Levi-Montalcini (RLM discovering the nerve growth factor (NGF. Today, NGF and its relatives, collectively designated neurotrophins, are well recognized as mediators of multiple biological phenomena in health and disease, ranging from the neurotrophic through immunotrophic and epitheliotrophic to metabotrophic effects. Consequently, NGF and other neurotrophins are implicated in the pathogenesis of a large spectrum of neuronal and non-neuronal diseases, from Alzheimer's and other neurodegenerative diseases to atherosclerosis and other cardiometabolic diseases. Recent studies demonstrated the therapeutic potentials of NGF in these diseases, including ocular and cutaneous diseases. Furthermore, NGF TrkA receptor antagonists emerged as novel drugs for pain, prostate and breast cancer, melanoma, and urinary bladder syndromes. Altogether, NGF's multiple potential in health and disease is briefly described here.

  1. Recovery Migration after Hurricanes Katrina and Rita: Spatial Concentration and Intensification in the Migration System

    Science.gov (United States)

    Fussell, Elizabeth; DeWaard, Jack

    2015-01-01

    Changes in the human migration systems of Hurricane Katrina- and Rita-affected Gulf of Mexico coastline counties provide an example of how climate change may affect coastal populations. Crude climate change models predict a mass migration of “climate refugees,” but an emerging literature on environmental migration suggests most migration will be short-distance and short-duration within existing migration systems, with implications for the population recovery of disaster-struck places. In this research, we derive a series of hypotheses on recovery migration predicting how the migration system of hurricane-affected coastline counties in the Gulf of Mexico was likely to have changed between the pre-disaster and the recovery periods. We test these hypotheses using data from the Internal Revenue Service on annual county-level migration flows, comparing the recovery period migration system (2007–2009) to the pre-disaster period (1999–2004). By observing county-to-county ties and flows we find that recovery migration was strong, as the migration system of the disaster-affected coastline counties became more spatially concentrated while flows within it intensified and became more urbanized. Our analysis demonstrates how migration systems are likely to be affected by the more intense and frequent storms anticipated by climate change scenarios with implications for the population recovery of disaster-affected places. PMID:26084982

  2. Recovery Migration After Hurricanes Katrina and Rita: Spatial Concentration and Intensification in the Migration System.

    Science.gov (United States)

    Curtis, Katherine J; Fussell, Elizabeth; DeWaard, Jack

    2015-08-01

    Changes in the human migration systems of the Gulf of Mexico coastline counties affected by Hurricanes Katrina and Rita provide an example of how climate change may affect coastal populations. Crude climate change models predict a mass migration of "climate refugees," but an emerging literature on environmental migration suggests that most migration will be short-distance and short-duration within existing migration systems, with implications for the population recovery of disaster-stricken places. In this research, we derive a series of hypotheses on recovery migration predicting how the migration system of hurricane-affected coastline counties in the Gulf of Mexico was likely to have changed between the pre-disaster and the recovery periods. We test these hypotheses using data from the Internal Revenue Service on annual county-level migration flows, comparing the recovery period migration system (2007-2009) with the pre-disaster period (1999-2004). By observing county-to-county ties and flows, we find that recovery migration was strong: the migration system of the disaster-affected coastline counties became more spatially concentrated, while flows within it intensified and became more urbanized. Our analysis demonstrates how migration systems are likely to be affected by the more intense and frequent storms anticipated by climate change scenarios, with implications for the population recovery of disaster-affected places.

  3. Hazardous substances releases associated with Hurricanes Katrina and Rita in industrial settings, Louisiana and Texas

    International Nuclear Information System (INIS)

    Ruckart, Perri Zeitz; Orr, Maureen F.; Lanier, Kenneth; Koehler, Allison

    2008-01-01

    The scientific literature concerning the public health response to the unprecedented hurricanes striking the Gulf Coast in August and September 2005 has focused mainly on assessing health-related needs and surveillance of injuries, infectious diseases, and other illnesses. However, the hurricanes also resulted in unintended hazardous substances releases in the affected states. Data from two states (Louisiana and Texas) participating in the Hazardous Substances Emergency Events Surveillance (HSEES) system were analyzed to describe the characteristics of hazardous substances releases in industrial settings associated with Hurricanes Katrina and Rita. HSEES is an active multi-state Web-based surveillance system maintained by the Agency for Toxic Substances and Disease Registry (ATSDR). In 2005, 166 hurricane-related hazardous substances events in industrial settings in Louisiana and Texas were reported. Most (72.3%) releases were due to emergency shut downs in preparation for the hurricanes and start-ups after the hurricanes. Emphasis is given to the contributing causal factors, hazardous substances released, and event scenarios. Recommendations are made to prevent or minimize acute releases of hazardous substances during future hurricanes, including installing backup power generation, securing equipment and piping to withstand high winds, establishing procedures to shutdown process operations safely, following established and up-to-date start-up procedures and checklists, and carefully performing pre-start-up safety reviews

  4. Tres cartas para la traición de Rita Hayworth

    Directory of Open Access Journals (Sweden)

    José Amícola

    1996-11-01

    Full Text Available El artículo trata la relación entre los manuscritos previos a la escritura de la primera novela de Manuel Puig y la novela terminada [de 1968]. El capítulo inserto cerca del final de la novela [en forma de'carta anónima'] habla asimismo de la voluntad de conformar una estructura armónica, donde surja un movimiento bipolar de ritmo distendido versus otro agitado, a la vez que obliga a la participación del lector en la tarea de la identidad del presunto remitente del anónimo. La segunda carta analizada [el último capítulo de la novela] nos lleva al centro de una crítica genética en la que se evidencia el trabajo de pulimiento del broche final, como clave de todo el texto. La tercera carta analizada aquí [borrador de carta del escritor a la actriz Rita Hayworth, de 1966], es un paratexto [es decir: un texto no ficcional independiente]. El borrador de esa carta a la actriz que da nombre a la obra sirve al geneticista como piedra de toque para descubrir la intención autorial con respecto al núcleo argumental de la novela, un núcleo que los esquemas pre-textuales anunciaban como 'la verdad'

  5. Os Episódios de Rita Patrício

    Directory of Open Access Journals (Sweden)

    Gustavo Rubim

    2014-12-01

    O texto propõe uma leitura do livro Episódios: da teorização estética em Fernando Pessoa, da au­toria de Rita Patrício. Datado de 2012, o livro só ficou realmente pronto e publicado em 2014. A leitura de­fende a originalidade deste exame minucioso dos textos de teoria estética e literária de Fernando Pessoa, tanto pela maneira como os trata autonomamente da obra poética e os estuda na sua escrita específica, quanto pelo efeito de deslocação dos tópicos habituais na análise do programa modernista português. A crí­tica do idealismo pessoano e da noção de obra enquanto totalidade or­gânica são sublinhados enquanto gestos condutores de toda a pesquisa. Propõem-se articulações com outros ensaios recentes que em Portugal procedem à revisão da crítica e da hermenêutica pes­soana.

  6. In vitro propagation of Phalaenopsis (Orchidaceae from protocorms, using the temporary inmersion system "RITA"

    Directory of Open Access Journals (Sweden)

    Jorge Mario Tirado

    2005-01-01

    Full Text Available In order to massively propagate Phalaenopsis orchids, three months old in vitro protocorms were transferred to RITA® vessels. The evaluation factors were the sucrose concentration in the culture medium and the frequency immersion. There was a set of five pairs of RITA® vessels with liquid culture medium containing sucrose at 0,15, 30, 45, 60 g/L. A half-strength MS medium plus vitamins, supplemented with vitamins and thidiazuron (5 mg/L was used. The experiment had two stages, each lasting two months. Each stage had a one minute immersion. The first stage had a four hour immersion frequency and the second one had an eight hour immersion frequency. Results showed that the best proliferating response was reached in a 15 g/L of sucrose medium with one minute of immersion time every four hours, resulting in 8,2 adventitious protocorms per protocorm per month. Key words: Phalaenopsis, protocorm, in vitro propagation, temporary immersion, RITA.

  7. Hazardous substances releases associated with Hurricanes Katrina and Rita in industrial settings, Louisiana and Texas

    Energy Technology Data Exchange (ETDEWEB)

    Ruckart, Perri Zeitz [Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA (United States)], E-mail: afp4@cdc.gov; Orr, Maureen F. [Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA (United States); Lanier, Kenneth; Koehler, Allison [Louisiana Department of Health and Hospitals, Office of Public Health, New Orleans, LA (United States)

    2008-11-15

    The scientific literature concerning the public health response to the unprecedented hurricanes striking the Gulf Coast in August and September 2005 has focused mainly on assessing health-related needs and surveillance of injuries, infectious diseases, and other illnesses. However, the hurricanes also resulted in unintended hazardous substances releases in the affected states. Data from two states (Louisiana and Texas) participating in the Hazardous Substances Emergency Events Surveillance (HSEES) system were analyzed to describe the characteristics of hazardous substances releases in industrial settings associated with Hurricanes Katrina and Rita. HSEES is an active multi-state Web-based surveillance system maintained by the Agency for Toxic Substances and Disease Registry (ATSDR). In 2005, 166 hurricane-related hazardous substances events in industrial settings in Louisiana and Texas were reported. Most (72.3%) releases were due to emergency shut downs in preparation for the hurricanes and start-ups after the hurricanes. Emphasis is given to the contributing causal factors, hazardous substances released, and event scenarios. Recommendations are made to prevent or minimize acute releases of hazardous substances during future hurricanes, including installing backup power generation, securing equipment and piping to withstand high winds, establishing procedures to shutdown process operations safely, following established and up-to-date start-up procedures and checklists, and carefully performing pre-start-up safety reviews.

  8. The multiple life of nerve growth factor: tribute to rita levi-montalcini (1909-2012).

    Science.gov (United States)

    Aloe, Luigi; Chaldakov, George N

    2013-03-01

    At the end of the 19(th) century, it was envisaged by Santiago Ramon y Cajal, but not, proven, that life at the neuronal level requires trophic support. The proof was obtained in the early 1950's by work initiated by Rita Levi-Montalcini (RLM) discovering the nerve growth factor (NGF). Today, NGF and its relatives, collectively designated neurotrophins, are well recognized as mediators of multiple biological phenomena in health and disease, ranging from the neurotrophic through immunotrophic and epitheliotrophic to metabotrophic effects. Consequently, NGF and other neurotrophins are implicated in the pathogenesis of a large spectrum of neuronal and non-neuronal diseases, from Alzheimer's and other neurodegenerative diseases to atherosclerosis and other cardiometabolic diseases. Recent studies demonstrated the therapeutic potentials of NGF in these diseases, including ocular and cutaneous diseases. Furthermore, NGF TrkA receptor antagonists emerged as novel drugs for pain, prostate and breast cancer, melanoma, and urinary bladder syndromes. Altogether, NGF's multiple potential in health and disease is briefly described here.

  9. Homage to Rita Levi-Montalcini, the queen of modern neuroscience.

    Science.gov (United States)

    Aloe, Luigi; Chaldakov, George N

    2013-08-01

    The first cell growth factor, nerve growth factor (NGF), was discovered by Rita Levi-Montalcini (RLM) in the early 1950s. Originally identified as neurite outgrowth-stimulating factor, later studies revealed that non-neuronal cells, including immune cells, endothelial cells, cardiomyocytes, pancreatic beta cells, prostate epithelial and adipose tissue cells, were also targets for and/or sources of NGF. Nerve growth factor is well recognised as mediating multiple biological phenomena, ranging from the neurotrophic through immunotrophic and epitheliotrophic to metabotrophic effects. Consequently, NGF and other members of the neurotrophin family are implicated in the pathogenesis of a large spectrum of neuronal and non-neuronal diseases, ranging from Alzheimer's and other neurodegenerative diseases to atherosclerosis and cardiometabolic disorders. Recent studies have demonstrated the therapeutic potentials of NGF in these conditions, including ocular and cutaneous diseases. NGF TrkA receptor antagonists emerged as novel drugs for pain, prostate and breast cancer, melanoma and urinary bladder syndromes. Here, we briefly describe the 'unpredictable' ideogenesis of the discovery of NGF, a eureka in the neuroscience. © 2013 International Federation for Cell Biology.

  10. Impacts of Hurricanes Katrina and Rita on the microbial landscape of the New Orleans area.

    Science.gov (United States)

    Sinigalliano, C D; Gidley, M L; Shibata, T; Whitman, D; Dixon, T H; Laws, E; Hou, A; Bachoon, D; Brand, L; Amaral-Zettler, L; Gast, R J; Steward, G F; Nigro, O D; Fujioka, R; Betancourt, W Q; Vithanage, G; Mathews, J; Fleming, L E; Solo-Gabriele, H M

    2007-05-22

    Floodwaters in New Orleans from Hurricanes Katrina and Rita were observed to contain high levels of fecal indicator bacteria and microbial pathogens, generating concern about long-term impacts of these floodwaters on the sediment and water quality of the New Orleans area and Lake Pontchartrain. We show here that fecal indicator microbe concentrations in offshore waters from Lake Pontchartrain returned to prehurricane concentrations within 2 months of the flooding induced by these hurricanes. Vibrio and Legionella species within the lake were more abundant in samples collected shortly after the floodwaters had receded compared with samples taken within the subsequent 3 months; no evidence of a long-term hurricane-induced algal bloom was observed. Giardia and Cryptosporidium were detected in canal waters. Elevated levels of fecal indicator bacteria observed in sediment could not be solely attributed to impacts from floodwaters, as both flooded and nonflooded areas exhibited elevated levels of fecal indicator bacteria. Evidence from measurements of Bifidobacterium and bacterial diversity analysis suggest that the fecal indicator bacteria observed in the sediment were from human fecal sources. Epidemiologic studies are highly recommended to evaluate the human health effects of the sediments deposited by the floodwaters.

  11. Inability of p53-reactivating compounds Nutlin-3 and RITA to overcome p53 resistance in tumor cells deficient in p53Ser46 phosphorylation.

    Science.gov (United States)

    Ma, Teng; Yamada, Shumpei; Ichwan, Solachuddin J A; Iseki, Sachiko; Ohtani, Kiyoshi; Otsu, Megumi; Ikeda, Masa-Aki

    2012-01-20

    The p53 tumor suppressor protein plays key roles in protecting cells from tumorigenesis. Phosphorylation of p53 at Ser46 (p53Ser46) is considered to be a crucial modification regulating p53-mediated apoptosis. Because the activity of p53 is impaired in most human cancers, restoration of wild-type p53 (wt-p53) function by its gene transfer or by p53-reactivating small molecules has been extensively investigated. The p53-reactivating compounds Nutlin-3 and RITA activate p53 in the absence of genotoxic stress by antagonizing the action of its negative regulator Mdm2. Although controversial, Nutlin-3 was shown to induce p53-mediated apoptosis in a manner independent of p53 phosphorylation. Recently, RITA was shown to induce apoptosis by promoting p53Ser46 phosphorylation. Here we examined whether Nutlin-3 or RITA can overcome resistance to p53-mediated apoptosis in p53-resistant tumor cell lines lacking the ability to phosphorylate p53Ser46. We show that Nutlin-3 did not rescue the apoptotic defect of a Ser46 phosphorylation-defective p53 mutant in p53-sensitive tumor cells, and that RITA neither restored p53Ser46 phosphorylation nor induced apoptosis in p53Ser46 phosphorylation-deficient cells retaining wt-p53. Furthermore, treatment with Nutlin-3 or RITA together with adenoviral p53 gene transfer also failed to induce apoptosis in p53Ser46 phosphorylation-deficient cells either expressing or lacking wt-p53. These results indicate that neither Nutlin-3 nor RITA in able to induce p53-mediated apoptosis in the absence of p53Ser46 phosphorylation. Thus, the dysregulation of this phosphorylation in tumor cells may be a critical factor that limits the efficacy of these p53-based cancer therapies. Copyright © 2011 Elsevier Inc. All rights reserved.

  12. RITA (Reactivating p53 and Inducing Tumor Apoptosis) is efficient against TP53abnormal myeloma cells independently of the p53 pathway.

    Science.gov (United States)

    Surget, Sylvanie; Descamps, Géraldine; Brosseau, Carole; Normant, Vincent; Maïga, Sophie; Gomez-Bougie, Patricia; Gouy-Colin, Nadège; Godon, Catherine; Béné, Marie C; Moreau, Philippe; Le Gouill, Steven; Amiot, Martine; Pellat-Deceunynck, Catherine

    2014-06-14

    The aim of this study was to evaluate the efficacy of the p53-reactivating drugs RITA and nutlin3a in killing myeloma cells. A large cohort of myeloma cell lines (n = 32) and primary cells (n = 21) was used for this study. This cohort contained cell lines with various TP53 statuses and primary cells with various incidences of deletion of chromosome 17. Apoptosis was evaluated using flow cytometry with Apo2.7 staining of the cell lines or via the loss of the myeloma-specific marker CD138 in primary cells. Apoptosis was further confirmed by the appearance of a subG1 peak and the activation of caspases 3 and 9. Activation of the p53 pathway was monitored using immunoblotting via the expression of the p53 target genes p21, Noxa, Bax and DR5. The involvement of p53 was further studied in 4 different p53-silenced cell lines. Both drugs induced the apoptosis of myeloma cells. The apoptosis that was induced by RITA was not related to the TP53 status of the cell lines or the del17p status of the primary samples (p = 0.52 and p = 0.80, respectively), and RITA did not commonly increase the expression level of p53 or p53 targets (Noxa, p21, Bax or DR5) in sensitive cells. Moreover, silencing of p53 in two TP53(mutated) cell lines failed to inhibit apoptosis that was induced by RITA, which confirmed that RITA-induced apoptosis in myeloma cells was p53 independent. In contrast, apoptosis induced by nutlin3a was directly linked to the TP53 status of the cell lines and primary samples (p RITA, in contrast to nutlin3a, effectively induced apoptosis in a subset of MM cells independently of p53. The findings and could be of interest for patients with a 17p deletion, who are resistant to current therapies.

  13. After Hurricanes Katrina and Rita: gender differences in health and religiosity in middle-aged and older adults.

    Science.gov (United States)

    Brown, Jennifer Silva; Cherry, Katie E; Marks, Loren D; Jackson, Erin M; Volaufova, Julia; Lefante, Christina; Jazwinski, S Michal

    2010-11-01

    We examined health-related quality of life in adults in the Louisiana Health Aging Study (LHAS) after Hurricanes Katrina and Rita (HK/R) that made landfall on the U.S. Gulf Coast region in 2005. Analyses of pre- and post-disaster SF-36 scores yielded changes in physical function and bodily pain. Mental health scores were lower for women than men. Gender differences were observed in religious beliefs and religious coping, favoring women. Religious beliefs and religious coping were negatively correlated with physical function, implying that stronger reliance on religiosity as a coping mechanism may be more likely among those who are less physically capable.

  14. CREACIÓN DE UN METAVERSO EN OPENSIM PARA LA UNIVERSIDAD DISTRITAL DENTRO DE LA RED RITA-UD

    Directory of Open Access Journals (Sweden)

    Nicolás Torres Vallejo

    2013-01-01

    Full Text Available Este paper contempla el montaje de un segmento de red inalámbrico para la red RITA-UD con el fin de brindar acceso a contenidos multimedia a través de un mundo virtual creado en OPENSIM. Los contenidos de las emisiones de streaming se encuentran almacenados en un servidor ubicado en el centro de computación de alto desempeño, CECAD. Al tiempo  que se realizaron pruebas de streaming multicast, se capturaron dichas transmisiones mediante el sniffer de paquetes WireShark con el fin de determinar parámetros de QoS que caractericen el canal.

  15. Clinician‐selected Electronic Information Resources do not Guarantee Accuracy in Answering Primary Care Physicians’ Information Needs. A review of: McKibbon, K. Ann, and Douglas B. Fridsma. “Effectiveness of Clinician‐selected Electronic Information Resources for Answering Primary Care Physicians’ Information Needs.” Journal of the American Medical Informatics Association 13.6 (2006: 653‐9.

    Directory of Open Access Journals (Sweden)

    Martha Ingrid Preddie

    2008-03-01

    Full Text Available Objective – To determine if electronic information resources selected by primary care physicians improve their ability to answer simulated clinical questions.Design – An observational study utilizing hour‐long interviews and think‐aloud protocols.Setting – The offices and clinics of primary care physicians in Canada and the United States.Subjects – Twenty‐five primary care physicians of whom 4 were women, 17 were from Canada, 22 were family physicians,and 24 were board certified.Methods – Participants provided responses to 23 multiple‐choice questions. Each physician then chose two questions and looked for the answers utilizing information resources of their own choice. The search processes, chosen resources and search times were noted. These were analyzed along with data on the accuracy of the answers and certainties related to the answer to each clinical question prior to the search.Main results – Twenty‐three physicians sought answers to 46 simulated clinical questions. Utilizing only electronic information resources, physicians spent a mean of 13.0 (SD 5.5 minutes searching for answers to the questions, an average of 7.3(SD 4.0 minutes for the first question and 5.8 (SD 2.2 minutes to answer the second question. On average, 1.8 resources were utilized per question. Resources that summarized information, such as the Cochrane Database of Systematic Reviews, UpToDate and Clinical Evidence, were favored 39.2% of the time, MEDLINE (Ovid and PubMed 35.7%, and Internet resources including Google 22.6%. Almost 50% of the search and retrieval strategies were keyword‐based, while MeSH, subheadings and limiting were used less frequently. On average, before searching physicians answered 10 of 23 (43.5% questions accurately. For questions that were searched using clinician‐selected electronic resources, 18 (39.1% of the 46 answers were accurate before searching, while 19 (42.1% were accurate after searching. The difference of

  16. Self-Paced Interactive Multimedia Courseware: A Learning Support Resource for Enhancing Electronic Theses and Dissertations Development

    Science.gov (United States)

    Essel, Harry Barton; Osei-Poku, Patrick; Tachie-Menson, Akosua; Opoku-Asare, Nana Afia

    2016-01-01

    Submission of Electronic Theses and Dissertations (ETDs) by postgraduate students has become a common phenomenon in learning environments globally. The purpose of ETDs is to train postgraduate students as knowledge workers in online publishing and also extend their skills beyond word processing. The challenge however, is that many postgraduate…

  17. Web Accessibility Issues for Higher & Further Education. EDNER (Formative Evaluation of the Distributed National Electronic Resource) Project. Issues Paper.

    Science.gov (United States)

    Manchester Metropolitan Univ. (England).

    This issues paper, sixth in a series of eight, is intended to distill formative evaluation questions on topics that are central to the development of the higher and further education information environment in the United Kingdom. In undertaking formative evaluation studies, the Formative Evaluation of the Distributed National Electronic Resource…

  18. Analyzing the Academic Research Trends by Using University Digital Resources: A Bibliometric Study of Electronic Commerce in China

    Science.gov (United States)

    Fatima, Anam; Abbas, Asad; Ming, Wan; Zaheer, Ahmad Nawaz; Akhtar, Masood-ul-Hassan

    2017-01-01

    Technology plays a vital role in every field of life especially in business and education. Electronic commerce (EC) begins in the year of 1991 right after internet was introduced for commercial use. It is known to be the 12th five years' plan (2011 to 2015) of Chinese Ministry of Industry and Information Technology. The main "objective"…

  19. Green Supply Chain Collaboration for Fashionable Consumer Electronics Products under Third-Party Power Intervention—A Resource Dependence Perspective

    OpenAIRE

    Jiuh-Biing Sheu

    2014-01-01

    Under third-party power intervention (TPPI), which increases uncertainty in task environments, complex channel power interplays and restructuring are indispensable among green supply chain members as they move toward sustainable collaborative relationships for increased viability and competitive advantage. From the resource dependence perspective, this work presents a novel conceptual model to investigate the influence of political and social power on channel power restructuring and induced ...

  20. Geomorphic and ecological effects of Hurricanes Katrina and Rita on coastal Louisiana marsh communities

    Science.gov (United States)

    Piazza, Sarai C.; Steyer, Gregory D.; Cretini, Kari F.; Sasser, Charles E.; Visser, Jenneke M.; Holm, Guerry O.; Sharp, Leigh A.; Evers, D. Elaine; Meriwether, John R.

    2011-01-01

    Hurricanes Katrina and Rita made landfall in 2005, subjecting the coastal marsh communities of Louisiana to various degrees of exposure. We collected data after the storms at 30 sites within fresh (12), brackish/intermediate (12), and saline (6) marshes to document the effects of saltwater storm surge and sedimentation on marsh community dynamics. The 30 sites were comprised of 15 pairs. Most pairs contained one site where data collection occurred historically (that is, prestorms) and one Coastwide Reference Monitoring System site. Data were collected from spring 2006 to fall 2007 on vegetative species composition, percentage of vegetation cover, aboveground and belowground biomass, and canopy reflectance, along with discrete porewater salinity, hourly surface-water salinity, and water level. Where available, historical data acquired before Hurricanes Katrina and Rita were used to compare conditions and changes in ecological trajectories before and after the hurricanes. Sites experiencing direct and indirect hurricane influences (referred to in this report as levels of influence) were also identified, and the effects of hurricane influence were tested on vegetation and porewater data. Within fresh marshes, porewater salinity was greater in directly impacted areas, and this heightened salinity was reflected in decreased aboveground and belowground biomass and increased cover of disturbance species in the directly impacted sites. At the brackish/intermediate marsh sites, vegetation variables and porewater salinity were similar in directly and indirectly impacted areas, but porewater salinity was higher than expected throughout the study. Interestingly, directly impacted saline marsh sites had lower porewater salinity than indirectly impacted sites, but aboveground biomass was greater at the directly impacted sites. Because of the variable and site-specific nature of hurricane influences, we present case studies to help define postdisturbance baseline conditions in

  1. Estudo etnobotânico de plantas medicinais na comunidade de Santa Rita, Ituiutaba – MG

    Directory of Open Access Journals (Sweden)

    Juliana Aparecida Povh

    2013-07-01

    Full Text Available http://dx.doi.org/10.5007/2175-7925.2013v26n3p231 O objetivo deste artigo foi inventariar as plantas utilizadas na medicina popular pelos membros da comunidade rural de Santa Rita, no município de Ituiutaba - MG. A avaliação foi realizada por meio de entrevistas, com um questionário semiestruturado, e posterior coleta das plantas indicadas pelos informantes. Foram realizadas 47 entrevistas e 127 espécies foram listadas, pertencentes a 55 famílias de Angiospermas. Para obtenção dos dados quantitativos foi calculada a porcentagem de Concordância de Usos Principais (CUP de cada espécie; para identificar as indicações terapêuticas de maior importância, utilizou-se o Fator de Consenso dos Informantes (FCI. A CUP demonstrou que 5,5% das plantas citadas são amplamente utilizadas pela comunidade. As famílias botânicas predominantes foram Lamiaceae e Asteraceae, com 14 e 13 registros, respectivamente. A indicação de uso predominante envolveu, principalmente, afecções relacionadas a distúrbio emocional, conforme indicado pelo FCI. Salienta-se que 60,7% das plantas citadas neste artigo são espécies exóticas; desse modo, se faz necessário mais estudos para catalogar o conhecimento sobre as plantas medicinais nativas dessa região.

  2. Hurricane Rita surge data, southwestern Louisiana and southeastern Texas, September to November 2005

    Science.gov (United States)

    McGee, Benton D.; Goree, Burl B.; Tollett, Roland W.; Woodward, Brenda K.; Kress, Wade H.

    2006-01-01

    Pressure transducers and high-water marks were used to document the inland water levels related to storm surge generated by Hurricane Rita in southwestern Louisiana and southeastern Texas. On September 22-23, 2005, an experimental monitoring network consisting of 47 pressure transducers (sensors) was deployed at 33 sites over an area of about 4,000 square miles to record the timing, extent, and magnitude of inland hurricane storm surge and coastal flooding. Sensors were programmed to record date and time, temperature, and barometric or water pressure. Water pressure was corrected for changes in barometric pressure and salinity. Elevation surveys using global-positioning systems and differential levels were used to relate all storm-surge water-level data, reference marks, benchmarks, sensor measuring points, and high-water marks to the North American Vertical Datum of 1988 (NAVD 88). The resulting data indicated that storm-surge water levels over 14 feet above NAVD 88 occurred at three locations and rates of water-level rise greater than 5 feet per hour occurred at three locations near the Louisiana coast. Quality-assurance measures were used to assess the variability and accuracy of the water-level data recorded by the sensors. Water-level data from sensors were similar to data from co-located sensors, permanent U.S. Geological Survey streamgages, and water-surface elevations performed by field staff. Water-level data from sensors at selected locations were compared to corresponding high-water mark elevations. In general, the water-level data from sensors were similar to elevations of high quality high-water marks, while reporting consistently higher than elevations of lesser quality high-water marks.

  3. Post disaster resilience: Racially different correlates of depression symptoms among hurricane Katrina-Rita volunteers.

    Science.gov (United States)

    Nicdao, Ethel G; Noel, La Tonya; Ai, Amy L; Plummer, Carol; Groff, Sara

    2013-01-01

    The present analyses examined the differential risks of and protective factors against depressive symptoms of African American and Non-Hispanic White American student volunteers, respectively after Hurricanes Katrina and Rita (H-KR). A total sample of 554 student volunteers were recruited from mental health professional programs at five universities located in the Deep South, namely areas severely impacted by H-KR during fall semester 2005. The response rate was 91% (n = 505). African American respondents (n = 299) and Non-Hispanic White Americans (n = 206) completed the survey questionnaires. Respondents retrospectively provided information on peritraumatic emotional reactions and previous trauma that were recalled by H-KR and H-KR stressors. African American respondents reported higher levels of depressive symptoms (65.2%) than their Non-Hispanic White counterparts (34.8%). Hierarchical regression analyses revealed that disaster related stressors affected African Americans (p < 0.001), but not Non-Hispanic Whites. However, African Americans who experienced peritraumatic positive emotions had lower depression levels. Lower rates of recollection of prior traumas during H-KR were reported by African American respondents, whereas previous trauma recollections predicted symptoms among Non-Hispanic White Americans (p < 0.05). Exhibiting more optimism had lower depression levels among Non-Hispanic White Americans. Peritraumatic negative emotion was the only shared risk for depressive symptoms of both groups. Findings underscore racially different levels of depressive symptoms that may contribute to varying degrees of resilience among student volunteers. Future research and practice may address these racial differences by understanding the risk factors for depressive symptoms to develop appropriate interventions for racial groups, and cultivating the protective factors that contribute to resilience from traumatic experiences.

  4. Effects of hurricanes Katrina and Rita on Louisiana black bear habitat

    Science.gov (United States)

    Clark, Joseph D.; Murrow, Jennifer L.

    2012-01-01

    The Louisiana black bear (Ursus americanus luteolus) is comprised of 3 subpopulations, each being small, geographically isolated, and vulnerable to extinction. Hurricanes Katrina and Rita struck the Louisiana and Mississippi coasts in 2005, potentially altering habitat occupied by this federally threatened subspecies. We used data collected on radio-telemetered bears from 1993 to 1995 and pre-hurricane landscape data to develop a habitat model based on the Mahalanobis distance (D2) statistic. We then applied that model to post-hurricane landscape data where the telemetry data were collected (i.e., occupied study area) and where bear range expansion might occur (i.e., unoccupied study area) to quantify habitat loss or gain. The D2 model indicated that quality bear habitat was associated with areas of high mast-producing forest density, low water body density, and moderate forest patchiness. Cross-validation and testing on an independent data set in central Louisiana indicated that prediction and transferability of the model were good. Suitable bear habitat decreased from 348 to 345 km2 (0.9%) within the occupied study area and decreased from 34,383 to 33,891 km2 (1.4%) in the unoccupied study area following the hurricanes. Our analysis indicated that bear habitat was not significantly degraded by the hurricanes, although changes that could have occurred on a microhabitat level would be more difficult to detect at the resolution we used. We suggest that managers continue to monitor the possible long-term effects of these hurricanes (e.g., vegetation changes from flooding, introduction of toxic chemicals, or water quality changes).

  5. Assessing the Relationship Between Mental Distress and Tobacco Use in Post-Katrina and Rita Louisiana.

    Science.gov (United States)

    Mukherjee, Snigdha; Canterberry, Melanie; Yore, Jennifer B; Ledford, Edward Cannon; Carton, Thomas W

    2017-08-24

    The relationship between mental health status and smoking is complicated and often confounded by bi-directionality, yet most research on this relationship assumes exogeneity. The goal of this article is to implement an instrumental variable approach to (1) test the exogeneity assumption and (2) report on the association between mental health status and smoking post-disaster. This analysis utilizes the 2006 and 2007 Louisiana Behavioral Risk Factor Surveillance Survey to examine the link between mental distress and smoking in areas affected by Hurricanes Katrina and Rita. Residence in a hurricane-affected parish (county) was used as an instrumental variable for mental distress. Just over 22% of the sample resided in a hurricane-affected parish. Residents of hurricane-affected parishes were significantly more likely to report occasional and frequent mental distress. Residence in a hurricane-affected parish was not significantly associated with smoking status. With residence established as a salient instrumental variable for mental distress, the exogeneity assumption was tested and confirmed in this sample. A dose-response relationship existed between mental distress and smoking, with smoking prevalence increasing directly (and non-linearly) with mental distress. In this sample, the relationship between mental distress and smoking status was exogenous and followed a dose-response relationship, suggesting that the disasters did not result in an uptake of smoking initiation, but that the higher amounts of mental distress may lead to increased use among smokers. The findings suggest that tobacco control programs should devise unique strategies to address mentally distressed populations.

  6. Kinematic structure of convective-scale elements in the rainbands of Hurricanes Katrina and Rita (2005)

    Science.gov (United States)

    Hence, Deanna A.; Houze, Robert A.

    2008-08-01

    Airborne Doppler radar data collected during the Hurricane Rainband and Intensity Change Experiment (RAINEX) show the convective-scale air motions embedded in the principal rainbands of hurricanes Katrina and Rita. These embedded convective cells have overturning updrafts and low-level downdrafts (originating at 2-4 km) that enter the rainband on its radially outward side and cross over each other within the rainband as well as a strong downdraft emanating from upper levels (6+ km) on the radially inward side. These vertical motion structures repeat from one convective cell to another along each rainband. The resulting net vertical mass transport is upward in the upwind portion of the band and greatest in the middle sector of the principal rainband, where the updraft motions contribute generally to an increase of potential vorticity below the 3-4 km level. Because the convective cells in the middle sector are systematically located radially just inside the secondary horizontal wind maximum (SHWM), the local increase in vorticity implied by the convective mass transport is manifest locally as an increase in the strength of the SHWM at midlevels (˜4 km). The overturning updrafts of the convective cells tilt, stretch, and vertically transport vorticity such that the convergence of the vertical flux of vorticity strengthens the vorticity anomaly associated with the SHWM. This process could strengthen the SHWM by several meters per second per hour, and may explain how high wave number convective-scale features can influence a low wave number feature such as the principal rainband, and subsequently influence the primary vortex.

  7. Mineral resources of Peru's ancient societies

    Science.gov (United States)

    Brooks, W.E.

    2003-01-01

    Northern Peru has an exceptionally rich archaeological heritage that includes metalwork, ceramics and textiles. The success of at least a half-dozen pre-Columbian societies dating back 3,000 years and subsequent Spanish colonization in the 1400s has rested on the effective use of northern Peru's abundant resources. In the summer of 2000, my son Matt and I learned about that connection firsthand by volunteering at the Santa Rita B archaeological site in the Chao Valley near Trujillo in northern Peru. Riding donkey-back through the Andes and talking with local people, we got our hands dirty in the rich archaeology and geology of the area. We were able to correlate mineral occurrences to their various roles in society - opening a window into the region's fascinating past. From construction to metallurgy, pre-Columbian societies flourished and advanced because of their understanding and use of the available mineral resources.

  8. Share and share alike: encouraging the reuse of academic resources through the Scottish electronic Staff Development Library

    Directory of Open Access Journals (Sweden)

    Lorna M. Campbell

    2001-12-01

    Full Text Available The Scottish electronic Staff Development Library (http://www.sesdl.scotcit.acuk is an ongoing collaborative project involving the Universities of Edinburgh, Paisley and Strathclyde which has been funded by SHEFC as part of their current ScotCIT Programme (http:llwww.scotcit.ac.uk. This project is being developed in response to the increasing demand for flexible, high-quality staff development materials.

  9. Hurricane Rita and the destruction of Holly Beach, Louisiana: Why the chenier plain is vulnerable to storms

    Science.gov (United States)

    Sallenger, A.H.; Wright, C.W.; Doran, K.; Guy, K.; Morgan, K.

    2009-01-01

    Hurricane Rita devastated gulf-front communities along the western Louisiana coast in 2005. LIDAR (light detection and ranging) topographic surveys and aerial photography collected before and after the storm showed the loss of every structure within the community of Holly Beach. Average shoreline change along western Louisiana's 140-km-long impacted shore was -23.3 ?? 30.1 m of erosion, although shoreline change in Holly Beach was substantially less, and erosion was not pervasive where the structures were lost. Before the storm, peak elevations of the dunes, or berms in the absence of dunes, along the impacted shore averaged 1.6 m. The storm surge, which reached 3.5 m just east of Holly Beach, completely inundated the beach systems along the impacted western Louisiana shore. The high surge potential and low land elevations make this coast extremely vulnerable to hurricanes. In fact, most of the western Louisiana shore impacted by Rita will be completely inundated by the storm surge of a worst-case Saffi r-Simpson category 1 hurricane. All of this shore will be inundated by worst-case category 2-5 storms. ?? 2009 The Geological Society of America.

  10. Nonlinear terms in storm surge predictions: Effect of tide and shelf geometry with case study from Hurricane Rita

    Science.gov (United States)

    Rego, JoãO. L.; Li, Chunyan

    2010-06-01

    This study applied the finite volume coastal ocean model (FVCOM) to the storm surge induced by Hurricane Rita along the Louisiana-Texas coast. The model was calibrated for tides and validated with observed water levels. Peak water levels were shown to be lower than expected for a landfall at high tide. For low- and high-tide landfalls, nonlinear effects due to tide-surge coupling were constructive and destructive to total storm tide, respectively, and their magnitude reached up to 70% of the tidal amplitude in the Rita application. Tide-surge interaction was further examined using a standard hurricane under idealized scenarios to evaluate the effects of various shelf geometries, tides, and landfall timings (relative to tide). Nonlinearity was important between landfall position and locations within 2.5 × radius of maximum winds. On an idealized wide continental shelf, nonlinear effects reached up to 80% of the tidal amplitude with an S2 tide and up to 47% with a K1 tide. Increasing average depths by 4 m reduced nonlinear effects to 41% of the tidal amplitude; increasing the slope by a factor of 3 produced nonlinearities of just 26% of tide (both with a K1 tide). The nonlinear effect was greatest for landfalls at low tide, followed by landfalls at high tide and then by landfalls at midebb or midflood.

  11. Mammals of medium and large size in Santa Rita do Sapucaí, Minas Gerais, southeastern Brazil

    Directory of Open Access Journals (Sweden)

    Eduardo, A. A.

    2009-01-01

    Full Text Available The diversity of Brazilian vertebrates is regarded among the highest in the world. However, the biologicaldiversity is still mostly unknown and a good part of it is seriously threatened by human activities. This study aimed toinventory the medium and large size mammals present in the Reserva Biológica de Santa Rita do Sapucaí, an Atlanticforest reserve located in Santa Rita do Sapucaí, southeastern Brazil. Sand-plots, photographic traps and searches foranimal tracks on pre-existent trails in the area, were carried out once every two months between May 2006 andFebruary 2007. The sand-plots and tracks were inspected during five consecutive days per sampling. We obtained 108records of 15 species, mostly of carnivorans. Two confirmed species are threatened with extinction in Brazil (Callithrixaurita and Leopardus pardalis. The results suggest that the sampled reserve has high species richness and plays animportant role in conservation of mammals in this landscape, including species threatened with extinction.

  12. Success factors for implementing and sustaining a mature electronic medical record in a low-resource setting: a case study of iSanté in Haiti.

    Science.gov (United States)

    deRiel, E; Puttkammer, N; Hyppolite, N; Diallo, J; Wagner, S; Honoré, J G; Balan, J G; Celestin, N; Vallès, J S; Duval, N; Thimothé, G; Boncy, J; Coq, N R L; Barnhart, S

    2018-03-01

    Electronic health information systems, including electronic medical records (EMRs), have the potential to improve access to information and quality of care, among other things. Success factors and challenges for novel EMR implementations in low-resource settings have increasingly been studied, although less is known about maturing systems and sustainability. One systematic review identified seven categories of implementation success factors: ethical, financial, functionality, organizational, political, technical and training. This case study applies this framework to iSanté, Haiti's national EMR in use in more than 100 sites and housing records for more than 750 000 patients. The author group, consisting of representatives of different agencies within the Haitian Ministry of Health (MSPP), funding partner the Centers for Disease Control and Prevention (CDC) Haiti, and implementing partner the International Training and Education Center for Health (I-TECH), identify successes and lessons learned according to the seven identified categories, and propose an additional cross-cutting category, sustainability. Factors important for long-term implementation success of complex information systems are balancing investments in hardware and software infrastructure upkeep, user capacity and data quality control; designing and building a system within the context of the greater eHealth ecosystem with a plan for interoperability and data exchange; establishing system governance and strong leadership to support local system ownership and planning for system financing to ensure sustainability. Lessons learned from 10 years of implementation of the iSanté EMR system are relevant to sustainability of a full range of increasingly interrelated information systems (e.g. for laboratory, supply chain, pharmacy and human resources) in the health sector in low-resource settings. © The Author 2017. Published by Oxford University Press in association with The London School of Hygiene

  13. Santa Rita Experimental Range: 100 years (1903 to 2003) of accomplishments and contributions; conference proceedings; 2003 October 30-November 1; Tucson, AZ

    Science.gov (United States)

    Mitchel P. McClaran; Peter F. Ffolliott; Carleton B. Edminster

    2003-01-01

    The purpose of this conference was to celebrate the 100 years of accomplishments and contributions of the Santa Rita Experimental Range, the longest continuously operating research area dedicated to the sustainable management of North American rangelands. The conference consisted of one-and-a-half days of invited synthesis papers and contributed poster presentations...

  14. Impacts of Hurricane Rita on the beaches of western Louisiana: Chapter 5D in Science and the storms-the USGS response to the hurricanes of 2005

    Science.gov (United States)

    Stockdon, Hilary F.; Fauver, Laura A.; Sallenger,, Asbury H.; Wright, C. Wayne

    2007-01-01

    Hurricane Rita made landfall as a category 3 storm in western Louisiana in late September 2005, 1 month following Hurricane Katrina's devastating landfall in the eastern part of the State. Large waves and storm surge inundated the lowelevation coastline, destroying many communities and causing extensive coastal change including beach, dune, and marsh erosion.

  15. Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents

    NARCIS (Netherlands)

    Michaelis, M.; Rothweiler, F.; Agha, B.; Barth, S.; Voges, Y.; Loeschmann, N.; von Deimling, A.; Breitling, R.; Doerr, H. Wilhelm; Roedel, F.; Speidel, D.; Cinatl, J.; Cinatl Jr., J.; Stephanou, A.

    Adaptation of wild-type p53 expressing UKF-NB-3 cancer cells to the murine double minute 2 inhibitor nutlin-3 causes de novo p53 mutations at high frequency (13/20) and multi-drug resistance. Here, we show that the same cells respond very differently when adapted to RITA, a drug that, like nutlin-3,

  16. Hurricanes Katrina and Rita: Temporary Emergency Impact Aid Provided Education Support for Displaced Students. Report to the Congressional Requesters. GAO-11-839

    Science.gov (United States)

    Scott, George A.

    2011-01-01

    In August and September 2005, Hurricanes Katrina and Rita devastated large portions of the U.S. Gulf Coast, resulting in nearly 2,000 deaths and severe damage to 305,000 houses and apartments. Thousands of families relocated to communities throughout the United States and enrolled their children in local public or private schools. Some families…

  17. Selection and Evaluation of Electronic Resources Elektronik Kaynakların Seçimi ve Değerlendirilmesi

    Directory of Open Access Journals (Sweden)

    Doğan Atılgan

    2009-12-01

    Full Text Available Publication boom and issues related to controlling and accession of printed sources have created some problems after World War II. Consequently, publishing industry has encountered the problem of finding possible solution for emerged situation. Industry of electronic publishing has started to improve with the rapid increase of the price of printed sources as well as the problem of publication boom. The first effects of electronic publishing were appeared on the academic and scholarly publications then electronic publishing became a crucial part of all types of publications. As a result of these developments, collection developments and service policies of information centers were also significantly changed. In this article, after a general introduction about selection and evaluation processes of electronic publications, the subscribed databases by a state and a privately owned university in Turkey and their usage were examined. İkinci dünya savaşından sonra görülen yayın patlaması, basılı kaynakların denetim ve erişiminde sorunlar yaşanmasına neden olmuştur. Bu da yayıncılık sektöründe yeni arayışlara yol açmıştır. 1980’li yıllardan sonra basılı yayın fiyatlarındaki hızlı artış da bu etmenlere eklenince elektronik yayıncılık sektörü gelişmeye başlamıştır. Öncelikle bilimsel ve akademik yayınlarla başlayan elektronik yayın günümüzde tüm yayın türlerini kapsamaktadır. Yayıncılıktaki bu gelişim bilgi merkezlerinin derme geliştirme ve hizmet politikalarını da önemli ölçüde değiştirmiştir. Bu çalışmada elektronik yayınların seçim, değerlendirme ve sağlama konularında genel bir girişten sonra bir devlet üniversitesinin bir de özel üniversitenin abone olduğu veritabanları ve bu veri tabanlarının kullanımının değerlendirilmesi yapılmaktadır.

  18. The Walnut Gulch - Santa Rita Wildland Watershed-Scale LTAR Sites

    Science.gov (United States)

    Goodrich, D. C.; Heilman, P.; Scott, R. L.; Nearing, M. A.; Moran, M. S.; Nichols, M.; Vivoni, E. R.; Archer, S. R.; Biederman, J.; Naito, A. T.

    2015-12-01

    The 150 km2 Walnut Gulch Experimental Watershed (WGEW), a Long-Term Agroecosystem Research (LTAR) site, near Tombstone, Arizona was established in 1953 by the USDA-ARS Southwest Watershed Research Center in Tucson. It is one of the most intensively instrumented semiarid experimental watersheds in the world with elevation ranging from 1220 to 1950 m with mean annual temperature and precipitation equal to 17.7°C and 312 mm. Desert shrubs dominate the lower two thirds of the watershed and grasses the upper third. Spatial variation in precipitation is measured with a network of 88 weighing-type recording rain gauges. Surface runoff is quantified over a range of scales (0.002 to 0.06 km2) to characterize interactions between rainfall intensity, soils and vegetation at nine sub-watersheds. Channel network processes and rainfall spatial variability are studied using 11 nested watersheds (2 to 150 km2). Sediment from the small sub-watersheds is sampled. Meteorological, soil moisture and temperature, and energy/water/CO2 flux measurements are made within two vegetation/soil complexes. Parallel investigations dating back to 1974 have also been conducted on eight small experimental watersheds at the Santa Rita Experimental Range (SRER) 80 km west of Walnut Gulch. In contrast to the creosote bush-grass WGEW, the mesquite-grass SRER is publicly owned, which ensures control and consistent reporting of management for research purposes. A key LTAR objective is to contrast a "business as usual" to an alternate management strategy presumed to have the potential of significantly improving forage and livestock production and diversification of ecosystem services. Consequently, a new ARS-U. of Arizona-Arizona State U. partnership will assess the watershed-scale impacts of brush management, a common land use practice typically applied in conjunction with livestock grazing, on a suite of ecosystem services at the SRER including provisioning (forage production, water yield), supporting

  19. Regeneration of coastal marsh vegetation impacted by hurricanes Katrina and Rita

    Science.gov (United States)

    Middleton, B.A.

    2009-01-01

    The dynamics of plant regeneration via seed and vegetative spread in coastal wetlands dictate the nature of community reassembly that takes place after hurricanes or sea level rise. The objectives of my project were to evaluate the potential effects of saltwater intrusion and flooding of Hurricanes Katrina and Rita on seedling regeneration in coastal wetlands of the Gulf Coast. Specifically I tested hypotheses to determine for species in fresh, brackish and salt marshes of the Gulf Coast if 1) the pattern of seed germination and seedling recruitment differed with distance from the shoreline, and 2) seed germination and seedling recruitment for various species were reduced in higher levels of water depth and salinity. Regarding Hypothesis 1, seedling densities increased with distance from the shoreline in fresh and brackish water marshes while decreasing with distance from the shoreline in salt marshes. Also to test Hypothesis 1, I used a greenhouse seed bank assay to examine seed germination from seed banks collected at distances from the shoreline in response to various water depths and salinity levels using a nested factorial design. For all marsh types, the influence of water level and salinity on seed germination shifted with distance from the shoreline (i.e., three way interaction of the main effects of distance nested within site, water depth, and salinity). Data from the seed bank assay were also used to test Hypothesis 2. The regeneration of species from fresh, brackish, and salt marshes were reduced in conditions of high salinity and/or water, so that following hurricanes or sea level rise, seedling regeneration could be reduced. Among the species of these coastal marshes, there was some flexibility of response, so that at least some species were able to germinate in either high or low salinity. Salt marshes had a few fresher marsh species in the seed bank that would not germinate without a period of fresh water input (e.g., Sagittaria lancifolia) as well

  20. Utility of the electronic information resource UpToDate for clinical decision-making at bedside rounds.

    Science.gov (United States)

    Phua, J; See, K C; Khalizah, H J; Low, S P; Lim, T K

    2012-02-01

    Clinical questions often arise at daily hospital bedside rounds. Yet, little information exists on how the search for answers may be facilitated. The aim of this prospective study was, therefore, to evaluate the overall utility, including the feasibility and usefulness of incorporating searches of UpToDate, a popular online information resource, into rounds. Doctors searched UpToDate for any unresolved clinical questions during rounds for patients in general medicine and respiratory wards, and in the medical intensive care unit of a tertiary teaching hospital. The nature of the questions and the results of the searches were recorded. Searches were deemed feasible if they were completed during the rounds and useful if they provided a satisfactory answer. A total of 157 UpToDate searches were performed during the study period. Questions were raised by all ranks of clinicians from junior doctors to consultants. The searches were feasible and performed immediately during rounds 44% of the time. Each search took a median of three minutes (first quartile: two minutes, third quartile: five minutes). UpToDate provided a useful and satisfactory answer 75% of the time, a partial answer 17% of the time and no answer 9% of the time. It led to a change in investigations, diagnosis or management 37% of the time, confirmed what was originally known or planned 38% of the time and had no effect 25% of the time. Incorporating UpToDate searches into daily bedside rounds was feasible and useful in clinical decision-making.

  1. Satellite Assessment of Bio-Optical Properties of Northern Gulf of Mexico Coastal Waters Following Hurricanes Katrina and Rita.

    Science.gov (United States)

    Lohrenz, Steven E; Cai, Wei-Jun; Chen, Xiaogang; Tuel, Merritt

    2008-07-10

    The impacts of major tropical storms events on coastal waters include sediment resuspension, intense water column mixing, and increased delivery of terrestrial materials into coastal waters. We examined satellite imagery acquired by the Moderate Resolution Imaging Spectroradiometer (MODIS) ocean color sensor aboard the Aqua spacecraft following two major hurricane events: Hurricane Katrina, which made landfall on 29 August 2005, and Hurricane Rita, which made landfall on 24 September. MODIS Aqua true color imagery revealed high turbidity levels in shelf waters immediately following the storms indicative of intense resuspension. However, imagery following the landfall of Katrina showed relatively rapid return of shelf water mass properties to pre-storm conditions. Indeed, MODIS Aqua-derived estimates of diffuse attenuation at 490 nm (K_490) and chlorophyll (chlor_a) from mid-August prior to the landfall of Hurricane Katrina were comparable to those observed in mid-September following the storm. Regions of elevated K_490 and chlor_a were evident in offshore waters and appeared to be associated with cyclonic circulation (cold-core eddies) identified on the basis of sea surface height anomaly (SSHA). Imagery acquired shortly after Hurricane Rita made landfall showed increased water column turbidity extending over a large area of the shelf off Louisiana and Texas, consistent with intense resuspension and sediment disturbance. An interannual comparison of satellite-derived estimates of K_490 for late September and early October revealed relatively lower levels in 2005, compared to the mean for the prior three years, in the vicinity of the Mississippi River birdfoot delta. In contrast, levels above the previous three year mean were observed off Texas and Louisiana 7-10 d after the passage of Rita. The lower values of K_490 near the delta could be attributed to relatively low river discharge during the preceding months of the 2005 season. The elevated levels off Texas and

  2. RITA--Registry of Industrial Toxicology Animal data: the application of historical control data for Leydig cell tumors in rats.

    Science.gov (United States)

    Nolte, Thomas; Rittinghausen, Susanne; Kellner, Rupert; Karbe, Eberhard; Kittel, Birgit; Rinke, Matthias; Deschl, Ulrich

    2011-11-01

    Historical data for Leydig cell tumors from untreated or vehicle treated rats from carcinogenicity studies collected in the RITA database are presented. Examples are given for analyses of these data for dependency on variables considered to be of possible influence on the spontaneous incidence of Leydig cell tumors. In the 7453 male rats available for analysis, only one case of a Leydig cell carcinoma was identified. The incidence of Leydig cell adenomas differed markedly between strains. High incidences of close to 100% have been found in F344 rats, while the mean incidence was 4.2% in Sprague-Dawley rats and 13.7% in Wistar rats. Incidences in Wistar rats were highly variable, primarily caused by different sources of animals. Mean incidences per breeder varied from 2.8 to 39.9%. Analyses for the dependency on further parameters have been performed in Wistar rats. In breeders G and I, the Leydig cell tumor incidence decreased over the observation period and with increasing mean terminal body weight. The incidence of Leydig cell tumors increased with mean age at necropsy and was higher in studies with dietary admixture compared to gavage studies. These parameters had no effect on Leydig cell tumor incidence in breeders A and B. Animals from almost all breeders had a considerably higher mean age at necropsy when bearing a Leydig cell adenoma than animals without a Leydig cell adenoma. Studies with longitudinal trimming of the testes had a higher incidence than studies with transverse trimming. The observed dependencies and breeder differences are discussed and explanations are given. Consequences for the use of historical control data are outlined. With the retrospective analyses presented here we were able to confirm the published features of Leydig cell adenomas and carcinomas. This indicates that the RITA database is a valuable tool for analyses of tumors for their biological features. Furthermore, it demonstrates that the RITA database is highly beneficial for

  3. Satellite Assessment of Bio-Optical Properties of Northern Gulf of Mexico Coastal Waters Following Hurricanes Katrina and Rita

    Directory of Open Access Journals (Sweden)

    Merritt Tuel

    2008-07-01

    Full Text Available The impacts of major tropical storms events on coastal waters include sediment resuspension, intense water column mixing, and increased delivery of terrestrial materials into coastal waters. We examined satellite imagery acquired by the Moderate Resolution Imaging Spectroradiometer (MODIS ocean color sensor aboard the Aqua spacecraft following two major hurricane events: Hurricane Katrina, which made landfall on 29 August 2005, and Hurricane Rita, which made landfall on 24 September. MODIS Aqua true color imagery revealed high turbidity levels in shelf waters immediately following the storms indicative of intense resuspension. However, imagery following the landfall of Katrina showed relatively rapid return of shelf water mass properties to pre-storm conditions. Indeed, MODIS Aqua-derived estimates of diffuse attenuation at 490 nm (K_490 and chlorophyll (chlor_a from mid-August prior to the landfall of Hurricane Katrina were comparable to those observed in mid-September following the storm. Regions of elevated K_490 and chlor_a were evident in offshore waters and appeared to be associated with cyclonic circulation (cold-core eddies identified on the basis of sea surface height anomaly (SSHA. Imagery acquired shortly after Hurricane Rita made landfall showed increased water column turbidity extending over a large area of the shelf off Louisiana and Texas, consistent with intense resuspension and sediment disturbance. An interannual comparison of satellite-derived estimates of K_490 for late September and early October revealed relatively lower levels in 2005, compared to the mean for the prior three years, in the vicinity of the Mississippi River birdfoot delta. In contrast, levels above the previous three year mean were observed off Texas and Louisiana 7-10 d after the passage of Rita. The lower values of K_490 near the delta could be attributed to relatively low river discharge during the preceding months of the 2005 season. The elevated levels

  4. Dual targeting of wild-type and mutant p53 by small molecule RITA results in the inhibition of N-Myc and key survival oncogenes and kills neuroblastoma cells in vivo and in vitro.

    Science.gov (United States)

    Burmakin, Mikhail; Shi, Yao; Hedström, Elisabeth; Kogner, Per; Selivanova, Galina

    2013-09-15

    Restoration of the p53 function in tumors is a promising therapeutic strategy due to the high potential of p53 as tumor suppressor and the fact that established tumors depend on p53 inactivation for their survival. Here, we addressed the question whether small molecule RITA can reactivate p53 in neuroblastoma and suppress the growth of neuroblastoma cells in vitro and in vivo. The ability of RITA to inhibit growth and to induce apoptosis was shown in seven neuroblastoma cell lines. Mechanistic studies were carried out to determine the p53 dependence and the molecular mechanism of RITA-induced apoptosis in neuroblastoma, using cell viability assays, RNAi silencing, co-immunoprecipitation, qPCR, and Western blotting analysis. In vivo experiments were conducted to study the effect of RITA on human neuroblastoma xenografts in mice. RITA induced p53-dependent apoptosis in a set of seven neuroblastoma cell lines, carrying wild-type or mutant p53; it activated p53 and triggered the expression of proapoptotic p53 target genes. Importantly, p53 activated by RITA inhibited several key oncogenes that are high-priority targets for pharmacologic anticancer strategies in neuroblastoma, including N-Myc, Aurora kinase, Mcl-1, Bcl-2, Wip-1, MDM2, and MDMX. Moreover, RITA had a strong antitumor effect in vivo. Reactivation of wild-type and mutant p53 resulting in the induction of proapoptotic factors along with ablation of key oncogenes by compounds such as RITA may be a highly effective strategy to treat neuroblastoma. ©2013 AACR.

  5. Comprehensive evaluation of electronic medical record system use and user satisfaction at five low-resource setting hospitals in ethiopia.

    Science.gov (United States)

    Tilahun, Binyam; Fritz, Fleur

    2015-05-25

    Electronic medical record (EMR) systems are increasingly being implemented in hospitals of developing countries to improve patient care and clinical service. However, only limited evaluation studies are available concerning the level of adoption and determinant factors of success in those settings. The objective of this study was to assess the usage pattern, user satisfaction level, and determinants of health professional's satisfaction towards a comprehensive EMR system implemented in Ethiopia where parallel documentation using the EMR and the paper-based medical records is in practice. A quantitative, cross-sectional study design was used to assess the usage pattern, user satisfaction level, and determinant factors of an EMR system implemented in Ethiopia based on the DeLone and McLean model of information system success. Descriptive statistical methods were applied to analyze the data and a binary logistic regression model was used to identify determinant factors. Health professionals (N=422) from five hospitals were approached and 406 responded to the survey (96.2% response rate). Out of the respondents, 76.1% (309/406) started to use the system immediately after implementation and user training, but only 31.7% (98/309) of the professionals reported using the EMR during the study (after 3 years of implementation). Of the 12 core EMR functions, 3 were never used by most respondents, and they were also unaware of 4 of the core EMR functions. It was found that 61.4% (190/309) of the health professionals reported over all dissatisfaction with the EMR (median=4, interquartile range (IQR)=1) on a 5-level Likert scale. Physicians were more dissatisfied (median=5, IQR=1) when compared to nurses (median=4, IQR=1) and the health management information system (HMIS) staff (median=2, IQR=1). Of all the participants, 64.4% (199/309) believed that the EMR had no positive impact on the quality of care. The participants indicated an agreement with the system and information

  6. The effects of Hurricanes Katrina and Rita on seabed polycyclic aromatic hydrocarbon dynamics in the Gulf of Mexico.

    Science.gov (United States)

    Mitra, Siddhartha; Lalicata, Joseph J; Allison, Mead A; Dellapenna, Timothy M

    2009-06-01

    To assess the extent to which Hurricanes Katrina and Rita affected polycyclic aromatic hydrocarbons (PAH) in the Gulf of Mexico (GOM), sediment cores were analyzed in late 2005 from: a shallow shelf, a deeper shelf, and a marsh station. Sediment geochronology, fabric, and geochemistry show that the 2005 storms deposited approximately 10cm of sediment to the surface of a core at 5-12A. Bulk carbon geochemistry and PAH isomers in this top layer suggest that the source of sediment to the top portion of core 5-12A was from a relatively more marine area. Particulate PAHs in the marsh core (04M) appeared unaffected by the storms while sediments in the core from Station 5-1B (deeper shelf) were affected minimally (some possible storm-derived deposition). Substantial amounts of PAH-laden particles may have been displaced from the seabed in shallow areas of the water column in the GOM by these 2005 storms.

  7. Recent infection testing algorithm (RITA) applied to new HIV diagnoses in England, Wales and Northern Ireland, 2009 to 2011.

    Science.gov (United States)

    Aghaizu, A; Murphy, G; Tosswill, J; DeAngelis, D; Charlett, A; Gill, O N; Ward, H; Lattimore, S; Simmons, Rd; Delpech, V

    2014-01-16

    In 2009, Public Health England (PHE) introduced the routine application of a recent infection testing algorithm (RITA) to new HIV diagnoses, where a positive RITA result indicates likely acquisition of infection in the previous six months. Laboratories submit serum specimens to PHE for testing using the HIV 1/2gO AxSYM assay modified for the determination of HIV antibody avidity. Results are classified according to avidity index and data on CD₄ count, antiretroviral treatment and the presence of an AIDS-defining illness. Between 2009 and 2011, 38.4% (6,966/18,134) of new HIV diagnoses in England, Wales and Northern Ireland were tested. Demographic characteristics of those tested were similar to all persons with diagnosed HIV. Overall, recent infection was 14.7% (1,022/6,966) and higher among men who have sex with men (MSM) (22.3%, 720/3,223) compared with heterosexual men and women (7.8%, 247/3,164). Higher proportions were among persons aged 15-24 years compared with those ≥50 years (MSM 31.2% (139/445) vs 13.6% (42/308); heterosexual men and women 17.3% (43/249) vs 6.2% (31/501)). Among heterosexual men and women, black Africans were least likely to have recent infection compared with whites (4.8%, 90/1,892 vs 13.3%, 97/728; adjusted odds ratio: 0.6; 95% CI: 0.4-0.9). Our results indicate evidence of ongoing HIV transmission during the study period, particularly among MSM.

  8. Cooperação no APL de Santa Rita do Sapucaí.

    Directory of Open Access Journals (Sweden)

    Ana Rosa de Sousa

    2015-02-01

    Full Text Available Neste trabalho, apresentam-se os principais resultados de pesquisa na qual se investigaram os construtos explicativos das relações de cooperação entre as empresas integrantes do arranjo produtivo local (APL localizado na cidade de Santa Rita do Sapucaí, em Minas Gerais. Para tanto, recuperaram-se alguns aspectos da gênese, do desenvolvimento e da configuração do referido arranjo. Posteriormente, foi elaborada uma proposta teórico-metodológica que serviu de referência para a produção de explicações sobre relações entre os construtos cooperação, confiança, benefícios, entre outros. Para testar e validar a referida proposta, aplicaram-se duas técnicas de análise multivariada: análise fatorial e regressão polinomial. As análises dos resultados da pesquisa evidenciaram a existência de correlações que indicam percepção positiva dos gestores em relação à governança promovida no âmbito do arranjo produtivo e aos benefícios advindos da cooperação. Estes últimos são vistos pelos gestores como geradores de algumas vantagens individuais e coletivas para as empresas participantes da pesquisa. Finalmente, os resultados desta pesquisa contrariam algumas formulações da proposta teórico-metodológica utilizada para explicar as relações de confiança construídas entre as empresas que atuam numa mesma base territorial. Indicam ainda que esse APL exemplificaria bem a importância de dois elementos institucionais: a governança (no caso, Sindicato das Indústrias de Aparelhos Elétricos, Eletrônicos e Similares do Vale da Eletrônica – Sindvel – e poder público local e a interveniência de entidades educacionais que, além de assegurarem a qualificação da mão de obra, assumiram a tarefa de incubar empresas. Não parece inapropriado afirmar que o APL deve a sua criação e, mesmo, o seu desenvolvimento à atuação desses entes, conjuminada com a ação de pessoas visionárias, que ocuparam cargos diretivos

  9. Randomized Controlled Trial of Electronic Care Plan Alerts and Resource Utilization by High Frequency Emergency Department Users with Opioid Use Disorder

    Directory of Open Access Journals (Sweden)

    Niels Rathlev, MD

    2016-01-01

    Full Text Available Introduction: There is a paucity of literature supporting the use of electronic alerts for patients with high frequency emergency department (ED use. We sought to measure changes in opioid prescribing and administration practices, total charges and other resource utilization using electronic alerts to notify providers of an opioid-use care plan for high frequency ED patients. Methods: This was a randomized, non-blinded, two-group parallel design study of patients who had 1 opioid use disorder and 2 high frequency ED use. Three affiliated hospitals with identical electronic health records participated. Patients were randomized into “Care Plan” versus “Usual Care groups”. Between the years before and after randomization, we compared as primary outcomes the following: 1 opioids (morphine mg equivalents prescribed to patients upon discharge and administered to ED and inpatients; 2 total medical charges, and the numbers of; 3 ED visits, 4 ED visits with advanced radiologic imaging (computed tomography [CT] or magnetic resonance imaging [MRI] studies, and 5 inpatient admissions. Results: A total of 40 patients were enrolled. For ED and inpatients in the “Usual Care” group, the proportion of morphine mg equivalents received in the post-period compared with the pre-period was 15.7%, while in the “Care Plan” group the proportion received in the post-period compared with the pre-period was 4.5% (ratio=0.29, 95% CI [0.07-1.12]; p=0.07. For discharged patients in the “Usual Care” group, the proportion of morphine mg equivalents prescribed in the post-period compared with the pre-period was 25.7% while in the “Care Plan” group, the proportion prescribed in the post-period compared to the pre-period was 2.9%. The “Care Plan” group showed an 89% greater proportional change over the periods compared with the “Usual Care” group (ratio=0.11, 95% CI [0.01-0.092]; p=0.04. Care plans did not change the total charges, or, the numbers

  10. There is a Relationship between Resource Expenditures and Reference Transactions in Academic Libraries. A Review of: Dubnjakovic, A. (2012. Electronic resource expenditure and the decline in reference transaction statistics in academic libraries. Journal of Academic Librarianship, 38(2, 94-100. doi:10.1016/j.acalib.2012.01.001

    Directory of Open Access Journals (Sweden)

    Annie M. Hughes

    2013-03-01

    Full Text Available Objective – To provide an analysis of the impact of expenditures on electronic resourcesand gate counts on the increase or decrease in reference transactions.Design – Analysis of results of existing survey data from the National Center for Educational Statistics (NCES 2006 Academic Library Survey(ALS.Setting – Academic libraries in the United States.Subjects – 3925 academic library respondents.Methods – The author chose to use survey data collected from the 2006 ALS conducted bythe NCES. The survey included data on various topics related to academic libraries, but in the case of this study, the author chose to analyze three of the 193 variables included. The three variables: electronic books expenditure, computer hardware and software, and expenditures on bibliographic utilities, were combined into one variable called electronic resource expenditure. Gate counts were also considered as a variable. Electronic resource expenditure was also split as a variable into three groups: low, medium, and high. Multiple regression analysis and general linear modeling, along with tests of reliability, were employed. Main Results – The author determined that low, medium, and high spenders with regard to electronic resources exhibited differences in gate counts, and gate counts have an effect on reference transactions in any given week. Gate counts tend to not have much of an effect on reference transactions for the higher spenders, and higher spenders tend to have a higher number of reference transactions overall. Low spenders have lower gate counts and also a lower amount of reference transactions.Conclusion – The findings from this study show that academic libraries spending more on electronic resources also tend to have an increase with regard to reference transactions. The author also concludes that library spaces are no longer the determining factor with regard to number of reference transactions. Spending more on electronic resources is

  11. Global application of disorders of sex development-related electronic resources: e-learning, e-consultation and e-information sharing.

    Science.gov (United States)

    Muscarella, Miriam; Kranenburg-van Koppen, Laura; Grijpink-van den Biggelaar, Kalinka; Drop, Stenvert L S

    2014-01-01

    The past 20 years have seen proliferation of electronic (e) resources that promote improved understanding of disorders of sex development (DSD): e-learning for physicians and trainees, e-consultation between clinicians, and e-information for families and affected individuals. Recent e-learning advances have emerged from the European Society for Pediatric Endocrinology's online learning portal for current physicians and trainees. Developed with attention to developing clinical competencies incorporating learning theory, and presenting material that represents international best practice, this e-learning portal offers advances in training, making information more accessible for clinicians and trainees. Multiple levels of instruction, authentic case examples, collaborative forums for physicians and trainees, individualized feedback and user-friendly tools represent advances in trainee and physician learning that can take place in any location. e-consultation is an emerging tool that aims to connect physicians with specialists experienced in DSD care. Although it faces logistical challenges, e-consultation carries the potential to improve DSD care, especially in remote areas with limited access to DSD specialists. e-information for families and patients of all ages is widely accessible online, often with focus on DSD biology, medical care, and psychological and social support. e-information tools aid self-management and support of those affected by DSD. Efforts to improve these resources should aim to map information to individual users, incorporate optimally clear nomenclature, and continue as a 'shared enterprise' of clinicians, affected individuals, families and researchers. Improving the quality of DSD-related e-learning and e-information and developing e-consultation carries the potential to transform DSD care and support for patients, families and physicians worldwide. © 2014 S. Karger AG, Basel.

  12. Ranking Medical Terms to Support Expansion of Lay Language Resources for Patient Comprehension of Electronic Health Record Notes: Adapted Distant Supervision Approach.

    Science.gov (United States)

    Chen, Jinying; Jagannatha, Abhyuday N; Fodeh, Samah J; Yu, Hong

    2017-10-31

    Medical terms are a major obstacle for patients to comprehend their electronic health record (EHR) notes. Clinical natural language processing (NLP) systems that link EHR terms to lay terms or definitions allow patients to easily access helpful information when reading through their EHR notes, and have shown to improve patient EHR comprehension. However, high-quality lay language resources for EHR terms are very limited in the public domain. Because expanding and curating such a resource is a costly process, it is beneficial and even necessary to identify terms important for patient EHR comprehension first. We aimed to develop an NLP system, called adapted distant supervision (ADS), to rank candidate terms mined from EHR corpora. We will give EHR terms ranked as high by ADS a higher priority for lay language annotation-that is, creating lay definitions for these terms. Adapted distant supervision uses distant supervision from consumer health vocabulary and transfer learning to adapt itself to solve the problem of ranking EHR terms in the target domain. We investigated 2 state-of-the-art transfer learning algorithms (ie, feature space augmentation and supervised distant supervision) and designed 5 types of learning features, including distributed word representations learned from large EHR data for ADS. For evaluating ADS, we asked domain experts to annotate 6038 candidate terms as important or nonimportant for EHR comprehension. We then randomly divided these data into the target-domain training data (1000 examples) and the evaluation data (5038 examples). We compared ADS with 2 strong baselines, including standard supervised learning, on the evaluation data. The ADS system using feature space augmentation achieved the best average precision, 0.850, on the evaluation set when using 1000 target-domain training examples. The ADS system using supervised distant supervision achieved the best average precision, 0.819, on the evaluation set when using only 100 target

  13. Crossing Canadian Cultural Borders: A study of the Aboriginal/White Stereotypical Relations in George Ryga's The Ecstasy of Rita Joe

    Directory of Open Access Journals (Sweden)

    Maram M. Samman

    2017-12-01

    Full Text Available This paper traces the intercultural journey of a young Aboriginal girl into the hegemonic white society. Rita Joe crossed the imaginary border that separates her reserve from the other Canadian society living in the urban developed city. Through this play, George Ryga aims at achieving liberation and social equality for the Aboriginals who are considered a colonized minority in their land. The research illustrates how Ryga represented his personal version of the colonial Aboriginal history to provide an empowering body narrative that supports their identity in the present and resists the erosion of their culture and tradition. The play makes very strong statements to preserve the family, history and local heritage against this forced assimilation. It tells the truth as its playwright saw it. The play is about the trail of Rita Joe after she moved from her reserve in pursuit of the illusion of the city where she thought she would find freedom and social equality. In fact the audience and the readers are all on trial. Ryga is pointing fingers at everyone who is responsible for the plights of the Aboriginals as it is clear in the play. He questions the Whites’ stereotypical stand against the Aboriginals. The play is a direct criticism of the political, social and cultural systems in Canada. The paper reveals Aboriginals' acts of opposition to racism, assimilation and colonization as represented in The Ecstasy of Rita Joe.

  14. Impact of two interventions on timeliness and data quality of an electronic disease surveillance system in a resource limited setting (Peru: a prospective evaluation

    Directory of Open Access Journals (Sweden)

    Quispe Jose A

    2009-03-01

    Full Text Available Abstract Background A timely detection of outbreaks through surveillance is needed in order to prevent future pandemics. However, current surveillance systems may not be prepared to accomplish this goal, especially in resource limited settings. As data quality and timeliness are attributes that improve outbreak detection capacity, we assessed the effect of two interventions on such attributes in Alerta, an electronic disease surveillance system in the Peruvian Navy. Methods 40 Alerta reporting units (18 clinics and 22 ships were included in a 12-week prospective evaluation project. After a short refresher course on the notification process, units were randomly assigned to either a phone, visit or control group. Phone group sites were called three hours before the biweekly reporting deadline if they had not sent their report. Visit group sites received supervision visits on weeks 4 & 8, but no phone calls. The control group sites were not contacted by phone or visited. Timeliness and data quality were assessed by calculating the percentage of reports sent on time and percentage of errors per total number of reports, respectively. Results Timeliness improved in the phone group from 64.6% to 84% in clinics (+19.4 [95% CI, +10.3 to +28.6]; p Conclusion Regular phone reminders significantly improved timeliness of reports in clinics and ships, whereas supervision visits led to improved data quality only among clinics. Further investigations are needed to establish the cost-effectiveness and optimal use of each of these strategies.

  15. The provenance and Sm/Nd Model ages of siliciclastic supracrustal rocks of the Faina and Santa Rita Greenstone belts, Goias, Brazil

    International Nuclear Information System (INIS)

    Resende, Marcelo Goncalves; Jost, Hardy; Lima, Bruno Eustaquio Moreira; Teixeira, Alexandre de Amorim

    1999-01-01

    The Faina and Santa Rita greenstone belts are two N 60 deg C W trending synclinoria separated by a N 30 deg C E strike-slip fault and rest allochtonous on the adjacent Uva and Caicara granite-gneiss complexes. The belts are made up of lower metakomatiites, followed by metabasalts and thick metasedimentary sequences deposited under contrasting paleogeographic settings. In Faina, the sequence consists of two complete shelf cycles, the first resting on basalts by an erosional unconformity. In Santa Rita, the basalts give gradually place to carbonaceous metashales, unconformably overlain by metarhythmites. Provenance based on trace element geochemistry, mineral chemistry of chloride and muscovite, source-are modeling and REE elements indicate that protoliths of the first shelf cycle of Faina and the carbonaceous metashales of Santa Rita formed under the influence of a source area dominated by mafic ultramafic rocks, whilst during the sedimentation of the second shelf cycle and the metarhythmites of Santa Rita the source-area was dominated by TTG granitoids. Sm-Nd model ages of the lower sedimentary packages vary between 3.0 and 2.8 Ga and the upper between 2.7 and 2.6 Ga. These intervals coincide, respectively, with the estimated age of the underlying, and with the Sm-Nd, Rb-Sr e U-Pb ages of the main granitoids and gneisses of the adjacent complexes. The same data indicate that, during the sedimentation of the first shelf cycle of Faina and the carbonaceous metashales of Santa Rita, both basins had independent source-areas, but shared the same source during the upper sections. Weathering nature and intensity of the source-area calculated by means of geochemical a data suggest that the dramatic change of provenance from the lower to the upper sections is due to the shift from tectonically stable to unstable regimes, interpreted as resulting from the emergence of the island arc whose roots are represented by the adjacent granite-gneiss complexes. (author)

  16. Hurricanes Katrina and Rita and the Department of Veterans Affairs: a conceptual model for understanding the evacuation of nursing homes.

    Science.gov (United States)

    Dobalian, Aram; Claver, Maria; Fickel, Jacqueline J

    2010-01-01

    Hurricanes Katrina and Rita exposed significant flaws in US preparedness for catastrophic events and the nation's capacity to respond to them. These flaws were especially evident in the affected disaster areas' nursing homes, which house a particularly vulnerable population of frail older adults. Although evacuation of a healthcare facility is a key preparedness activity, there is limited research on factors that lead to effective evacuation. Our review of the literature on evacuation is focused on developing a conceptual framework to study future evacuations rather than as a comprehensive assessment of prior work. This paper summarizes what is known thus far about disaster response activities of nursing homes following natural and human-caused disasters, describes a conceptual model to guide future inquiry regarding this topic, and suggests future areas of research to further understand the decision-making process of nursing home facilitators regarding evacuating nursing home residents. To demonstrate the utility of the conceptual model and to provide guidance about effective practices and procedures, this paper focuses on the responses of Veterans Health Administration (VHA) nursing homes to the 2 hurricanes. Quarantelli's conceptual framework, as modified by Perry and Mushkatel, is useful in guiding the development of central hypotheses related to the decision-making that occurred in VA nursing homes and other healthcare facilities following Hurricanes Katrina and Rita. However, we define evacuation somewhat differently to account for the fact that evacuation may, in some instances, be permanent. Thus, we propose modifying this framework to improve its applicability beyond preventive evacuation. We need to better understand how disaster plans can be adapted to meet the needs of frail elders and other residents in nursing homes. Moreover, we must address identified gaps in the scientific literature with respect to health outcomes by tracking outcomes over time

  17. The Santa Rita Shear Zone: Major Mesozoic deformation along the western flank of the White-Inyo Range, CA

    Energy Technology Data Exchange (ETDEWEB)

    Brudos, T.C.; Paterson, S.R. (Univ. of Southern California, Los Angeles, CA (United States). Dept. of Geological Sciences)

    1993-04-01

    The Santa Rita Shear Zone (SRSZ), briefly described by Ross (1967), deforms the western part of the 164 Ma Santa Rita Flat pluton (SRFP), located SSE of Big Pine, CA. The SRSZ comprises a subvertical zone of solid-state deformation (strike N15E) over an area at least 13 km long by 2--3 km wide. Exposure of the shear zone is limited to the north and west by overlying Quaternary volcanics and basin fill within the Late Cenozoic Owens Valley graben. The SRSZ is larger than its present outcrop extent: strain magnitudes are highest within the westernmost exposures. The SRSZ along this western margin is a continuous zone of deformation comprising a mm-scale solid-state foliation containing igneous feldspars flattened into ovals with > 10:1 aspect ratios. The authors have identified three dike phases within the SRFP: (1) minor NE-striking Phase 1 dikes, comprising cm-scale aplites; (2) widespread m-scale Phase 2 dikes, which strike N10E; and (3) m-scale NW-striking Phase 3 mafic dikes. The Phase 1 and Phase 3 dikes are pre- and post-tectonic respectively; observations described below indicate the Phase 2 dikes are syn- to post-deformation. Deformation becomes localized along the Phase 2 dikes -- which are parallel to the orientation of the main body of the shear zone. Solid-state fabrics imposed on the Phase 2 dikes formed at higher temperatures than those within the SRFP, and in the east the SRFP is deformed only within a few cm of the dikes. They surmise syntectonic emplacement of the dikes into dislocational surfaces within the SRSZ, followed by solid-state deformation of the cooling dikes. Several workers have suggested the dikes within the SRFP are part of the 148 Ma independence dike swarm (referring to the Phase 2 or 3 dikes). If correct, this correlation indicates a Jurassic age for the SRSZ. Radiometric analyses of the dikes are in progress.

  18. Online Resources

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Online Resources. Journal of Genetics. Online Resources. Volume 97. 2018 | Online resources. Volume 96. 2017 | Online resources. Volume 95. 2016 | Online resources. Volume 94. 2015 | Online resources. Volume 93. 2014 | Online resources. Volume 92. 2013 | Online resources ...

  19. Interactive Electronic Decision Trees for the Integrated Primary Care Management of Febrile Children in Low Resource Settings - Review of existing tools.

    Science.gov (United States)

    Keitel, Kristina; D'Acremont, Valérie

    2018-04-20

    The lack of effective, integrated diagnostic tools pose a major challenge to the primary care management of febrile childhood illnesses. These limitations are especially evident in low-resource settings and are often inappropriately compensated by antimicrobial over-prescription. Interactive electronic decision trees (IEDTs) have the potential to close these gaps: guiding antibiotic use and better identifying serious disease. This narrative review summarizes existing IEDTs, to provide an overview of their degree of validation, as well as to identify gaps in current knowledge and prospects for future innovation. Structured literature review in PubMed and Embase complemented by google search and contact with developers. Six integrated IEDTs were identified: three (eIMCI, REC, and Bangladesh digital IMCI) based on Integrated Management of Childhood Illnesses (IMCI); four (SL eCCM, MEDSINC, e-iCCM, and D-Tree eCCM) on Integrated Community Case Management (iCCM); two (ALMANACH, MSFeCARE) with a modified IMCI content; and one (ePOCT) that integrates novel content with biomarker testing. The types of publications and evaluation studies varied greatly: the content and evidence-base was published for two (ALMANACH and ePOCT), ALMANACH and ePOCT were validated in efficacy studies. Other types of evaluations, such as compliance, acceptability were available for D-Tree eCCM, eIMCI, ALMANACH. Several evaluations are still ongoing. Future prospects include conducting effectiveness and impact studies using data gathered through larger studies to adapt the medical content to local epidemiology, improving the software and sensors, and Assessing factors that influence compliance and scale-up. IEDTs are valuable tools that have the potential to improve management of febrile children in primary care and increase the rational use of diagnostics and antimicrobials. Next steps in the evidence pathway should be larger effectiveness and impact studies (including cost analysis) and

  20. Library resources on the Internet

    Science.gov (United States)

    Buchanan, Nancy L.

    1995-07-01

    Library resources are prevalent on the Internet. Library catalogs, electronic books, electronic periodicals, periodical indexes, reference sources, and U.S. Government documents are available by telnet, Gopher, World Wide Web, and FTP. Comparatively few copyrighted library resources are available freely on the Internet. Internet implementations of library resources can add useful features, such as full-text searching. There are discussion lists, Gophers, and World Wide Web pages to help users keep up with new resources and changes to existing ones. The future will bring more library resources, more types of library resources, and more integrated implementations of such resources to the Internet.

  1. The Muralla Pircada: an ancient Andean debris flow retention dam, Santa Rita B archaeological site, Chao Valley, Northern Peru

    Science.gov (United States)

    Brooks, William E.; Willett, Jason C.; Kent, Jonathan D.; Vasquez, Victor; Rosales, Teresa

    2005-01-01

    Debris flows caused by El Niño events, earthquakes, and glacial releases have affected northern Perú for centuries. The Muralla Pircada, a northeast-trending, 2.5 km long stone wall east of the Santa Rita B archaeological site (Moche-Chimú) in the Chao Valley, is field evidence that ancient Andeans recognized and, more importantly, attempted to mitigate the effects of debris flows. The Muralla is upstream from the site and is perpendicular to local drainages. It is 1–2 m high, up to 5 m wide, and is comprised of intentionally-placed, well-sorted, well-rounded, 20–30 cm cobbles and boulders from nearby streams. Long axes of the stones are gently inclined and parallel local drainage. Case-and-fill construction was used with smaller cobbles and pebbles used as fill. Pre-Muralla debris flows are indicated by meter-sized, angular boulders that were incorporated in-place into construction of the dam and are now exposed in breeches in the dam. Post-Muralla debris flows in the Chao Valley are indicated by meter-sized, angular boulders that now abut the retention dam.

  2. USGS environmental characterization of flood sediments left in the New Orleans area after Hurricanes Katrina and Rita, 2005--Progress Report

    Science.gov (United States)

    Plumlee, Geoffrey S.; Meeker, Gregory P.; Lovelace, John K.; Rosenbauer, Robert J.; Lamothe, Paul J.; Furlong, Edward T.; Demas, Charles R.

    2006-01-01

    Introduction: The flooding in the greater New Orleans area that resulted from Hurricanes Katrina and Rita in September, 2005, left behind accumulations of sediments up to many centimeters thick on streets, lawns, parking lots, and other flat surfaces. These flood sediment deposits have been the focus of extensive study by the US Environmental Protection Agency (EPA) and Louisiana Department of Environmental Quality (LDEQ) due to concerns that the sediments may contain elevated levels of heavy metals, organic contaminants, and microbes. The U.S. Geological Survey (USGS) is characterizing a limited number of flood sediment samples that were collected on September 15-16 and October 6-7, 2005, from the greater New Orleans area by personnel from the USGS Louisiana Water Science Center in Baton Rouge. Small samples (< 3 pints each) of wet to dry flood sediment were collected from 11 localities around downtown New Orleans on September 15, 2005, and two large samples (40 pints each) of wet flood sediment were collected from the Chalmette area on September 16. Twelve additional samples (8-10 pints each) were collected from New Orleans, Slidell, Rigolets, and Violet on October 6 and 7. The USGS characterization studies of these flood sediments are designed to produce data and interpretations regarding how the sediments and any contained contaminants may respond to environmental processes. This information will be of use to cleanup managers and DoI/USGS scientists assessing environmental impacts of the hurricanes and subsequent cleanup activities.

  3. A CONSTRUÇÃO DO LUGAR DE VIVER: PROJETO DE ASSENTAMENTO SANTA RITA EM JATAÍ – GO

    Directory of Open Access Journals (Sweden)

    Roberta Costa ROCHA

    2015-07-01

    Full Text Available A pesquisa da qual resulta este artigo tem como objeto o assentamento rural, enquanto modo de resistência camponesa para a sua permanência no campo, e a construção do lugar de viver nesse assentamento. Os atores da pesquisa são as famílias do Projeto de Assentamento Santa Rita, localizado no município de Jataí-GO, que, em um novo meio, constroem o seu lugar, dando-lhe significação e ressignificação enquanto lugar camponês. O estudo do lugar abre perspectivas para se pensar o viver e os processos de apropriação do espaço. Metodologicamente, os dados primários foram levantados através de entrevistas semiestruturadas e de aplicação de questionários e os dados secundários foram obtidos através de pesquisas bibliográficas, no intuito de aprofundar a discussão proposta.

  4. Observations of the structure and evolution of surface and flight-level wind asymmetries in Hurricane Rita (2005)

    Science.gov (United States)

    Rogers, Robert; Uhlhorn, Eric

    2008-11-01

    Knowledge of the magnitude and distribution of surface winds, including the structure of azimuthal asymmetries in the wind field, are important factors for tropical cyclone forecasting. With its ability to remotely measure surface wind speeds, the stepped frequency microwave radiometer (SFMR) has assumed a prominent role for the operational tropical cyclone forecasting community. An example of this instrument's utility is presented here, where concurrent measurements of aircraft flight-level and SFMR surface winds are used to document the wind field evolution over three days in Hurricane Rita (2005). The amplitude and azimuthal location (phase) of the wavenumber-1 asymmetry in the storm-relative winds varied at both levels over time. The peak was found to the right of storm track at both levels on the first day. By the third day, the peak in flight-level storm-relative winds remained to the right of storm track, but it shifted to left of storm track at the surface, resulting in a 60-degree shift between the surface and flight-level and azimuthal variations in the ratio of surface to flight-level winds. The asymmetric differences between the surface and flight-level maximum wind radii also varied, indicating a vortex whose tilt was increasing.

  5. A Cáritas brasileira e a Economia Popular Solidária: O Agente de Cáritas e a Caridade Libertadora (Brazilian Caritas and the Popular Solidarity Economy: The Agent of Caritas and the Charity Liberating) - DOI: 10.5752/P.2175-5841.2013v11n32p1506

    OpenAIRE

    Joannes Paulus Silva Forte; Alicia Ferreira Gonçalves

    2013-01-01

    O presente artigo analisa as ligações entre a Cáritas Brasileira e a Economia Popular Solidária a partir do trabalho do Agente de Cáritas. A problemática central do artigo remete às representações sociais que esses Agentes constroem em seus relatos sobre os princípios da Teologia da Libertação que norteiam os projetos em economia solidária da referida instituição religiosa. A metodologia de base qualitativa e etnográfica consistiu na realização da revisão bibliográfica, consulta a materiais i...

  6. Herpes - resources

    Science.gov (United States)

    Genital herpes - resources; Resources - genital herpes ... following organizations are good resources for information on genital herpes : March of Dimes -- www.marchofdimes.org/complications/sexually- ...

  7. Flora pteridofítica de fragmentos florestais do Parque Estadual de Vassununga – Santa Rita do Passa Quatro, SP. Pteridophyte flora of forest fragments in Vassununga State Park – Santa Rita do Passa Quatro, São Paulo, Brazil.

    Directory of Open Access Journals (Sweden)

    Áurea Maria Therezinha COLLI

    2014-06-01

    Full Text Available Este trabalho apresenta o levantamento da flora pteridofítica de dois fragmentos florestais do Parque Estadual de Vassununga, unidade de conservação localizada no município de Santa Rita do Passa Quatro, SP. Para tanto, foram realizadas onze excursões por caminhos e trilhas de fiscalização e de pesquisa. Na Gleba Maravilha, que apresenta vegetação de Floresta Estacional Semidecidual Montana e Floresta Estacional Semidecidual Aluvial com inundação temporária, foram encontradas 10 famílias, 18 gêneros e 35 espécies, sendo Pteridaceae, Thelypteridaceae, Aspleniaceae, e Polypodiaceae as famílias mais ricas com nove, sete, seis e cinco espécies, respectivamente. Na Gleba Capão da Várzea, onde ocorre a Floresta Paludosa e o Campo Antrópico, ocorreram nove famílias, 14 gêneros e 24 espécies, onde Thelypteridaceae e Polypodiaceae se apresentaram como as mais ricas, com oito e seis espécies, respectivamente. As Glebas do Parque Estadual de Vassununga com as suas diferentes fisionomias vegetais são áreas importantes para a conservação de pteridófitas na região nordeste do Estado de São Paulo, principalmente as típicas de Floresta Estacional Semidecidual Montana e de Floresta Paludosa como Blechnum brasiliense, Campyloneurum angustifolium, Cyclodium meniscioides, Osmunda regalis, Pityrogramma calomelanos e Thelypteris opposita. This work presents a survey on pteridophyte flora of two forest fragments in Vassununga State Park, a conservation unit located in the city of Santa Rita do Passa Quatro, São Paulo, Brazil. In order to carry out the survey, a series of eleven tours on old inspection and research trails were made. In the Maravilha Tract, which consists of Seasonal Semi-Deciduous Montane Forest and Seasonal Semideciduous Alluvial Forest with temporary flooding, 10 families, 18 genera, and 35 species were found, the richest families were Pteridaceae, Thelypteridaceae, Aspleniaceae, and Polypodiaceae, with nine, seven

  8. Pteridófitas do Parque Estadual de Vassununga, Santa Rita do Passa Quatro (SP, Brasil. Gleba Pé-de-Gigante. Pteridophytes from Vassununga State Park, Santa Rita do Passa Quatro, SP, Brazil. Gleba Pé-de-Gigante.

    Directory of Open Access Journals (Sweden)

    Áurea Maria Therezinha COLLI

    2004-12-01

    Full Text Available Neste trabalho foi realizado um levantamentode pteridófitas na Gleba Pé-de-Gigante do ParqueEstadual de Vassununga, localizado no municípiode Santa Rita do Passa Quatro, sob as coordenadas21º36’39,01054’’S e 47º37’03,46727’’W. As coletasforam realizadas em três trilhas, denominadasTrilha do Meliponário, Trilha do Córrego Paulicéiae Trilha da Torre. Foram reconhecidas 15 espéciesde pteridófitas pertencentes a 7 famílias. Dessas,as mais representativas foram Polypodiaceae eThelypteridaceae com quatro espécies cada,e Pteridaceae e Schizaeaceae que apresentaramduas espécies cada. Das 15 espécies registradas9 apresentam distribuição bastante restrita, ocorrendoapenas na Trilha do Córrego Paulicéia. Por outrolado, Microgramma squamulosa (Kaulf. de laSota, Pleopeltis angusta Willd e Polypodiumpolypodioides (L. Watt são as espécies deocorrência mais ampla. Em todas as trilhas hápteridófitas, sendo que a Trilha do CórregoPaulicéia é a mais rica, e a Trilha da Torre a maispobre em número de espécies. As pteridófitasocorrem no cerrado “sensu stricto”, cerradão e nafloresta de galeria. A maior diversidade de espéciesfoi encontrada na floresta de galeria.This work presents a pteridophyticalsurvey carried out at the Gleba Pé-de-Gigante ofthe Vassununga State Park, in the municipality ofSanta Rita do Passa Quatro (21º36’39.01054’’Sand 47º37’03.46727’’W. Collections wereaccomplished at three trails called “Trilha doMeliponário, Trilha do Córrego Paulicéia andTrilha da Torre ”. Fifteen species of pteridophytespertaining to 7 families were recognized. From these,the most representative ones were Polypodiaceaeand Thelypteridaceae, with 4 species each, andPteridaceae and Schizaeaceae, with two specieseach. From the 15 species registered, nine present avery restricted distribution occurring only in the“Trilha do Córrego Paulic��ia”, Microgrammasquamulosa, Pleopeltis angusta and

  9. Pteridófitas do Parque Estadual da Vassununga, Santa Rita do Passa Quatro (SP, Brasil. Glebas Capetinga Leste e Capetinga Oeste. Pteridophytes from Vassununga State Park, Santa Rita do Passa Quatro, SP, Brazil. Glebas Capetinga Leste and Capetinga Oeste.

    Directory of Open Access Journals (Sweden)

    Áurea Maria Therezinha COLLI

    2004-06-01

    Full Text Available Neste trabalho foi realizado umlevantamento de pteridófitas nas Glebas CapetingaLeste e Capetinga Oeste do Parque Estadual daVassununga, localizado no município de Santa Rita doPassa Quatro, sob as coordenadas 21º41’00’’ –21º41’21’’S e 47º34’37’’ – 47º39’39’’W. As coletasforam realizadas em quatro trilhas, denominadasTrilha da Mina, Trilha do Ribeirão Bebedouro,Trilha dos Jequitibás e Trilha do Córrego da Gruta.Foram reconhecidas 34 espécies de pteridófitaspertencentes a 10 famílias. Destas, as maisrepresentativas foram Polypodiaceae e Thelypteridaceaecom seis espécies cada e Aspleniaceae e Pteridaceaeque apresentaram cinco espécies cada. Das 34espécies registradas 10 apresentam distribuiçãobastante restrita, ocorrendo apenas na Trilha da Mina.Por outro lado, Polypodium polypodioides (L. Watt,Pteris denticulata var. denticulata Sw eThelypteris dentata (Forssk. E. St. John são asespécies de ocorrência mais ampla. Em todas astrilhas há pteridófitas, sendo que a Trilha da Minaé a mais rica e a Trilha do Ribeirão Bebedouro amais pobre em número de espécies. As pteridófitasocorrem na floresta estacional semidecidual e namata ciliar. A maior diversidade de espécies foiencontrada na floresta estacional semidecidual.This work presents a pteridophyticalsurvey carried out at Glebas Capetinga Leste andCapetinga Oeste at Vassununga State Park,Santa Rita do Passa Quatro county, (21º41’00’’ –21º41’21’’S and 47º34’37’’ – 47º39’39’’W.Collections were done at four places called “Trilhada Mina”, “Trilha do Ribeirão Bebedouro”, “Trilhados Jequitibás” and “Trilha do Córrego da Gruta.”Thirty-four species of pteridophytes pertaining to10 families were recognized. Among them, themost representative ones were Polypodiaceaeand Thelypteridaceae, with six species each,and Aspleniaceae and Pteridaceae, with fivespecies each. Considering the 34 species registered,10

  10. Usefulness of the admission electrocardiogram to predict long-term outcomes after non-ST-elevation acute coronary syndrome (from the FRISC II, ICTUS, and RITA-3 [FIR] Trials)

    DEFF Research Database (Denmark)

    Damman, Peter; Holmvang, Lene; Tijssen, Jan G P

    2012-01-01

    Instability in Coronary Artery Disease (FRISC II), Invasive Versus Conservative Treatment in Unstable Coronary Syndromes (ICTUS), and Randomized Intervention Trial of Unstable Angina 3 (RITA-3) patient-pooled database, 5,420 patients with NSTE-ACS with qualitative ECG data, of whom 2,901 had quantitative data...... the addition of quantitative characteristics to a model including qualitative characteristics. In conclusion, in the FRISC II, ICTUS, and RITA-3 NSTE-ACS patient-pooled data set, admission ECG characteristics provided long-term prognostic value for cardiovascular death or myocardial infarction. Quantitative...

  11. Multi-proxy Characterization of Two Recent Storm Deposits Attributed to Hurricanes Rita and Ike in the Chenier Plain of Southwestern Louisiana

    Science.gov (United States)

    Yao, Q.; Liu, K. B.; Ryu, J.

    2017-12-01

    The Chenier Plain in southwestern Louisiana owes its origin to dynamic depositional processes that are dominated by delta-switching of the Mississippi River to the east, while frequent hurricane activities also play an important role in its geomorphology and sedimentary history. However, despite several studies in the literature, the sediment-stratigraphic characteristics of recent or historic hurricane deposits are still not well documented from the Chenier Plain. In 2005 and 2008, Hurricane Rita (category 3) and Ike (category 2) made landfall on the coasts of Louisiana and Texas. Remote sensing images confirm that the Rockefeller Wildlife Refuge, located at the east end of the Louisiana Chenier Plain, was heavily impacted by both hurricanes. We analyzed the lithology and chemical stratigraphy of three 30 cm sediment monoliths (ROC-1, ROC-2, and ROC-3) recovered from a coastal saltmarsh in the Rockefeller Wildlife Refuge to identify the event deposits attributed to these two storms. Each monolith contains 2 distinct light-colored clastic sediment layers imbedded in brown organic clay. The loss-on-ignition and X-ray fluorescence results show that the hurricane layers have increased contents of Ca, Sr, Zr, and carbonates and decreased contents of water and organics. Surprisingly, despite its greater intensity and more severe impacts, Hurricane Rita left a much thinner storm deposit than did Hurricane Ike in all monoliths. Satellite data reveal that Hurricane Rita caused significant coastal erosion and shoreline recession, rendering the sampling sites much closer to the beach and ocean and therefore more prone to storm surges and overwash deposition than when Hurricane Ike struck three years later. Our results suggest that site-to-sea distance, which affects a study site's paleotempestological sensitivity, can play a bigger role in affecting the thicknesses of storm deposits than the intensity of the hurricane.

  12. The Use of Quality Benchmarking in Assessing Web Resources for the Dermatology Virtual Branch Library of the National electronic Library for Health (NeLH)

    OpenAIRE

    Boulos, MN Kamel; Roudsari, AV; Gordon, C; Gray, JA Muir

    2001-01-01

    Background In 1998, the U.K. National Health Service Information for Health Strategy proposed the implementation of a National electronic Library for Health to provide clinicians, healthcare managers and planners, patients and the public with easy, round the clock access to high quality, up-to-date electronic information on health and healthcare. The Virtual Branch Libraries are among the most important components of the National electronic Library for Health . They aim at creating online kno...

  13. Florística em um hectare de cerrado stricto sensu na ARIE - cerrado Pé-de-Gigante, Santa Rita do Passa Quatro, SP

    OpenAIRE

    Weiser, Veridiana de Lara; Godoy, Silvana Aparecida Pires de

    2001-01-01

    Foi realizado um levantamento florístico em um ha de cerrado stricto sensu, na parte norte da ARIE - Cerrado Pé-de-Gigante, Santa Rita do Passa Quatro, São Paulo. Foram coletados 428 espécimes em fase reprodutiva, em vinte e cinco excursões de coleta, durante o período de novembro de 1996 a abril de 1998. A listagem florística obtida apresenta 141 espécies, distribuídas em 109 gêneros e 49 famílias. As famílias mais representativas foram: Leguminosae, Asteraceae, Malpighiaceae e Myrtaceae. A ...

  14. Looking for the Silver Lining: Benefit Finding after Hurricanes Katrina and Rita in Middle-Aged, Older, and Oldest-Old Adults

    OpenAIRE

    Stanko, Katie E.; Cherry, Katie E.; Ryker, Kyle S.; Mughal, Farra; Marks, Loren D.; Brown, Jennifer Silva; Gendusa, Patricia F.; Sullivan, Marisa C.; Bruner, John; Welsh, David A.; Su, L. Joseph; Jazwinski, S. Michal

    2015-01-01

    Looking for potentially positive outcomes is one way that people cope with stressful events. In two studies, we examined perceived “silver linings” after the 2005 Hurricanes Katrina and Rita among indirectly affected adults. In Study 1, middle-aged (ages 47–64 years), older (ages 65–89 years), and oldest-old (ages 90–95 years) adults in the Louisiana Healthy Aging Study (LHAS) responded to an open-ended question on perceived silver linings in a longitudinal assessment carried out during the i...

  15. Pb and Sr isotopic systematics of some basalts and sulfides from the East Pacific Rise at 210N (project RITA)

    International Nuclear Information System (INIS)

    Vidal, P.; Clauer, N.

    1981-01-01

    Tholeiitic basalts and sulfide deposits from the 'Cyana' and 'Alvin' diving programs (RITA project) on the East Pacific Rise were analyzed for Pb and Sr isotopes. The basalt data plot within the field defined previously by other East Pacific Rise basalts ( 206 Pb/ 204 Pb: 18.35-18.58; 207 Pb/ 204 Pb: 15.48-15.53; 208 Pb/ 204 Pb: 37.8-38.1; 87 Sr/ 86 Sr: 0.7022-0.7025). Pb, U and Sr contents (approx. equal to 0.5, approx. equal to 0.05 and approx. equal to 110 ppm, respectively) and μ values (approx. equal to 6) are typical of MORB, whereas Th/U ratios (approx. equal to 3.5) are significantly higher. The Pb isotopic ratios of the sulfide samples are very homogeneous ( 206 Pb/ 204 Pb approx. equal to 18.47, 207 Pb/ 204 Pb approx. equal to 15.49, 208 Pb/ 204 Pb approx. equal to 37.90), and plot in the middle of the basalt field. This indicates that the sulfide Pb was derived from the basaltic crust without any significant contribution from either seawater or hemipelagic sediments, and the solutions from which the sulfiedes were deposited had uniform Pb isotopic composition. The Pb contents of three sulfide samples is relatively high (170-1310 ppm). The Sr contents of five sulfide samples are widely scattered from 12 to 210 ppm, with 87 Sr/ 86 Sr ratios intermediate between basaltic and seawater values (0.70554 +- 0.00005 to 0.70795 +- 0.00011). Leaching experiments show that both basalt-derived Sr and seawater Sr were present in the solutions which deposited the sulfides. In some cases, Sr was also adsorbed from seawater onto the sulfides following their deposition. Basalt-derived Sr and seawater Sr are also present in associated non-sulfide phases. (orig.)

  16. Sleep deprivation and adverse health effects in United States Coast Guard responders to Hurricanes Katrina and Rita.

    Science.gov (United States)

    Bergan, Timothy; Thomas, Dana; Schwartz, Erica; McKibben, Jodi; Rusiecki, Jennifer

    2015-12-01

    Disaster responders are increasingly called upon to assist in various natural and manmade disasters. A critical safety concern for this population is sleep deprivation; however, there are limited published data regarding sleep deprivation and disaster responder safety. We expanded upon a cross-sectional study of 2695 United States Coast Guard personnel who responded to Hurricanes Katrina and Rita. Data were collected via survey on self-reported timing and location of deployment, missions performed, health effects, medical treatment sought, average nightly sleep, and other lifestyle variables. We created a 4-level sleep deprivation metric based on both average nightly reported sleep (d5hours; >5hours) and length of deployment (d2weeks; >2weeks) to examine the association between sustained sleep deprivation and illnesses, injuries, and symptoms using logistic regression to calculate odds ratios (ORs) and 95% confidence intervals. The strongest, statistically significant positive ORs for the highest sleep deprivation category compared with the least sleep-deprived category were for mental health and neurologic effects, specifically depression (OR=6.76), difficulty concentrating (OR=8.33), and confusion (OR=11.34), and for dehydration (OR=9.0). Injuries most strongly associated with sleep deprivation were twists, sprains, and strains (OR=6.20). Most health outcomes evaluated had monotonically increasing ORs with increasing sleep deprivation, and P tests for trend were statistically significant. Agencies deploying disaster responders should understand the risks incurred to their personnel by sustained sleep deprivation. Improved planning of response efforts to disasters can reduce the potential for sleep deprivation and lead to decreased morbidity in disaster responders. Published by Elsevier Inc.

  17. Analysis on Current Situation and Countermeasure of Domestic Electronic Commerce Logistics in the Internet Age——Based on Resource Dependence Theory

    Directory of Open Access Journals (Sweden)

    Zhang Jiapeng

    2017-01-01

    Full Text Available This paper analyzes the status of electric business logistics in the current Internet era in China, and combines the SWOT analysis with AHP to do the empirical analysis, then puts forward the countermeasure that the electric business logistics resource should be shared based on the resource dependence theory. Through the empirical analysis, it is found that the disadvantages and opportunities of the logistics status are important in the Internet era.The resource sharing strategy based on the resource dependence theory is more scientific. The rational use of Internet technology in electric business logistics industry can achieve “sharing”. It is of great significance for its balanced development, intelligent development and optimization and development.

  18. The provenance and Sm/Nd Model ages of siliciclastic supracrustal rocks of the Faina and Santa Rita Greenstone belts, Goias, Brazil; Proveniencia e idades modelo Sm/Nd das rochas siliciclasticas arqueanas dos greenstone belts de Faina e Santa Rita, Goias

    Energy Technology Data Exchange (ETDEWEB)

    Resende, Marcelo Goncalves [Universidade Catolica de Brasilia, DF (Brazil); Jost, Hardy [Brasilia Univ., DF (Brazil). Inst. de Geociencias; Lima, Bruno Eustaquio Moreira; Teixeira, Alexandre de Amorim

    1999-09-01

    The Faina and Santa Rita greenstone belts are two N 60 deg C W trending synclinoria separated by a N 30 deg C E strike-slip fault and rest allochtonous on the adjacent Uva and Caicara granite-gneiss complexes. The belts are made up of lower metakomatiites, followed by metabasalts and thick metasedimentary sequences deposited under contrasting paleogeographic settings. In Faina, the sequence consists of two complete shelf cycles, the first resting on basalts by an erosional unconformity. In Santa Rita, the basalts give gradually place to carbonaceous metashales, unconformably overlain by metarhythmites. Provenance based on trace element geochemistry, mineral chemistry of chloride and muscovite, source-are modeling and REE elements indicate that protoliths of the first shelf cycle of Faina and the carbonaceous metashales of Santa Rita formed under the influence of a source area dominated by mafic ultramafic rocks, whilst during the sedimentation of the second shelf cycle and the metarhythmites of Santa Rita the source-area was dominated by TTG granitoids. Sm-Nd model ages of the lower sedimentary packages vary between 3.0 and 2.8 Ga and the upper between 2.7 and 2.6 Ga. These intervals coincide, respectively, with the estimated age of the underlying, and with the Sm-Nd, Rb-Sr e U-Pb ages of the main granitoids and gneisses of the adjacent complexes. The same data indicate that, during the sedimentation of the first shelf cycle of Faina and the carbonaceous metashales of Santa Rita, both basins had independent source-areas, but shared the same source during the upper sections. Weathering nature and intensity of the source-area calculated by means of geochemical a data suggest that the dramatic change of provenance from the lower to the upper sections is due to the shift from tectonically stable to unstable regimes, interpreted as resulting from the emergence of the island arc whose roots are represented by the adjacent granite-gneiss complexes. (author)

  19. Motion of the plasma critical layer during relativistic-electron laser interaction with immobile and comoving ion plasma for ion acceleration

    International Nuclear Information System (INIS)

    Sahai, Aakash A.

    2014-01-01

    We analyze the motion of the plasma critical layer by two different processes in the relativistic-electron laser-plasma interaction regime (a 0 >1). The differences are highlighted when the critical layer ions are stationary in contrast to when they move with it. Controlling the speed of the plasma critical layer in this regime is essential for creating low-β traveling acceleration structures of sufficient laser-excited potential for laser ion accelerators. In Relativistically Induced Transparency Acceleration (RITA) scheme, the heavy plasma-ions are fixed and only trace-density light-ions are accelerated. The relativistic critical layer and the acceleration structure move longitudinally forward by laser inducing transparency through apparent relativistic increase in electron mass. In the Radiation Pressure Acceleration (RPA) scheme, the whole plasma is longitudinally pushed forward under the action of the laser radiation pressure, possible only when plasma ions co-propagate with the laser front. In RPA, the acceleration structure velocity critically depends upon plasma-ion mass in addition to the laser intensity and plasma density. In RITA, mass of the heavy immobile plasma-ions does not affect the speed of the critical layer. Inertia of the bared immobile ions in RITA excites the charge separation potential, whereas RPA is not possible when ions are stationary

  20. Oil spills and other issues in the aftermath of Hurricanes Katrina and Rita : an overview

    International Nuclear Information System (INIS)

    Davis, D.W.

    2006-01-01

    The aftermath of Hurricane Katrina revealed weaknesses in the command, control, communications, and information dissemination functions within a variety of emergency response systems. This paper gave an outline of clean-up procedures involving hazardous materials. To date, clean-up crews have disposed of 8.0 million tonnes of an estimated 22.0 million tonnes of debris. The clean-up involved more than 1.3 million containerized hazardous materials; more than 230,000 damaged white goods; and nearly 43,000 damaged electronic goods. More than 3,400 samples of water, soil and air have been collected. Nearly 75 chemistry laboratories in schools have been inspected, and an additional 1500 emergency assessments of potential chemical releases were investigated. The floodwaters carried nearly 4.1 million litres of oil from a Chalmette refinery. Between September and the end of 2005, the Louisiana Oil Spill Coordinator's Office logged in 81 spill events in southwest Louisiana involving 22,000 bbls of crude. Six major, 3 medium and 131 minor events have occurred in southeast Louisiana. More than 3000 offshore platforms were shut down or damaged during the 2005 hurricane season. At least 115 platforms were destroyed and 52 were damaged. Onshore spills of concern included incidents at Murphy Oil Refinery; Bass Enterprise Production Company; Chevron at Port Fourchon; Venice Energy Services Company; Shell Pipeline; and Sundown Energy. It was concluded work done by the spill community will result in the development of more effective response plans. 23 refs

  1. How Students Learn: Ways of Thinking about "Good Learning" in HE. EDNER (Formative Evaluation of the Distributed National Electronic Resource) Project. Issues Paper.

    Science.gov (United States)

    Manchester Metropolitan Univ. (England).

    This issues paper, one of a series of eight, is intended to distill formative evaluation questions on topics that are central to the development of the higher and further education information environment in the United Kingdom. The topic of this first issues paper is a conceptual framework that can help members of a project (information resource)…

  2. 大學圖書館電子資源之需求分析與行銷策略之研究 A Study of Demands Analysis and Marketing Strategy of Electronic Resources in University Library

    Directory of Open Access Journals (Sweden)

    Huang-Yu Liu

    2008-03-01

    Full Text Available 電子資源的出現,使得知識載體有了新的突破,提高了使用者的便利性與即時性。對於圖書館而言,如何使電子資源的使用效益達到最高,必須思考一套有效的行銷策略。電子資源行銷概念應以讀者為導向,尊重讀者的資訊需求,並利用各種宣傳技巧,行銷電子資源,使圖書館能提供更完善的服務。本研究之目的旨在探討讀者的使用需求及電子資源的推廣策略,以獲致最有效益的行銷方式。研究對象以開南大學日間部四學院(商學院、運輸觀光學院、資訊學院、人文社會學院)學生為樣本,佐以缺口分析模型為分析架構,藉以找出個案中讀者/學生對於電子資源使用的真實需求,並進而歸納出提供服務的大學圖書館在其推廣或行銷服務上可有的因應策略。The emergence of electronic resources has made new breakthrough in knowledge carriers because of their ease of use, instant availability, and the characteristic of no time and space constraints. For public libraries to achieve maximum efficiency in its electronic resources, it is necessary to seek the most effective marketing strategies. Therefore, the marketing concept of the electronic resources should be reader oriented, such as respecting and understanding library user’s information needs. Libraries also need to utilize various media and techniques to market the electronic resources, so that more comprehensive services and experiences can be provided to readers. The purpose of this study is to investigate library user’s needs and promotion strategies of electronic resources in order to identify the most effective ways of marketing. This study focuses on the students of the four colleges (College of Business, College of Tourism, College of Information, and College of Humanities and Social Science in Kainan University as subjects in the survey questionnaire. It uses the Gap Analysis

  3. Oil spills and other issues in the aftermath of Hurricanes Katrina and Rita : an overview

    Energy Technology Data Exchange (ETDEWEB)

    Davis, D.W. [Lousiana Applied and Educational Research and Development Program, Baton Rouge, LA (United States)

    2006-07-01

    The aftermath of Hurricane Katrina revealed weaknesses in the command, control, communications, and information dissemination functions within a variety of emergency response systems. This paper gave an outline of clean-up procedures involving hazardous materials. To date, clean-up crews have disposed of 8.0 million tonnes of an estimated 22.0 million tonnes of debris. The clean-up involved more than 1.3 million containerized hazardous materials; more than 230,000 damaged white goods; and nearly 43,000 damaged electronic goods. More than 3,400 samples of water, soil and air have been collected. Nearly 75 chemistry laboratories in schools have been inspected, and an additional 1500 emergency assessments of potential chemical releases were investigated. The floodwaters carried nearly 4.1 million litres of oil from a Chalmette refinery. Between September and the end of 2005, the Louisiana Oil Spill Coordinator's Office logged in 81 spill events in southwest Louisiana involving 22,000 bbls of crude. Six major, 3 medium and 131 minor events have occurred in southeast Louisiana. More than 3000 offshore platforms were shut down or damaged during the 2005 hurricane season. At least 115 platforms were destroyed and 52 were damaged. Onshore spills of concern included incidents at Murphy Oil Refinery; Bass Enterprise Production Company; Chevron at Port Fourchon; Venice Energy Services Company; Shell Pipeline; and Sundown Energy. It was concluded work done by the spill community will result in the development of more effective response plans. 23 refs.

  4. Using Instrument Simulators and a Satellite Database to Evaluate Microphysical Assumptions in High-Resolution Simulations of Hurricane Rita

    Science.gov (United States)

    Hristova-Veleva, S. M.; Chao, Y.; Chau, A. H.; Haddad, Z. S.; Knosp, B.; Lambrigtsen, B.; Li, P.; Martin, J. M.; Poulsen, W. L.; Rodriguez, E.; Stiles, B. W.; Turk, J.; Vu, Q.

    2009-12-01

    Improving forecasting of hurricane intensity remains a significant challenge for the research and operational communities. Many factors determine a tropical cyclone’s intensity. Ultimately, though, intensity is dependent on the magnitude and distribution of the latent heating that accompanies the hydrometeor production during the convective process. Hence, the microphysical processes and their representation in hurricane models are of crucial importance for accurately simulating hurricane intensity and evolution. The accurate modeling of the microphysical processes becomes increasingly important when running high-resolution models that should properly reflect the convective processes in the hurricane eyewall. There are many microphysical parameterizations available today. However, evaluating their performance and selecting the most representative ones remains a challenge. Several field campaigns were focused on collecting in situ microphysical observations to help distinguish between different modeling approaches and improve on the most promising ones. However, these point measurements cannot adequately reflect the space and time correlations characteristic of the convective processes. An alternative approach to evaluating microphysical assumptions is to use multi-parameter remote sensing observations of the 3D storm structure and evolution. In doing so, we could compare modeled to retrieved geophysical parameters. The satellite retrievals, however, carry their own uncertainty. To increase the fidelity of the microphysical evaluation results, we can use instrument simulators to produce satellite observables from the model fields and compare to the observed. This presentation will illustrate how instrument simulators can be used to discriminate between different microphysical assumptions. We will compare and contrast the members of high-resolution ensemble WRF model simulations of Hurricane Rita (2005), each member reflecting different microphysical assumptions

  5. Application of electronic learning tools for training of specialists in the field of information technologies for enterprises of mineral resources sector

    Directory of Open Access Journals (Sweden)

    Е. В. Катунцов

    2017-08-01

    Full Text Available The article shows the advantages of using modern electronic learning tools in the training of specialists for the mineral and raw materials complex and considers the basic principles of organizing training using these tools. The experience of using electronic learning tools using foreign teaching materials and involving foreign professors is described. A special attention is given to the electronic learning environment of the Cisco Networking Academy – Cisco NetAcad. The experience of teaching at the Networking Academy of the Saint-Petersburg Mining University is described. Details are given to modern virtual environments for laboratory work, such as Cisco Packet Tracer, GNS3 and Emulated Virtual Environment. The experience of using electronic learning technologies at the University of Economics of Bratislava is considered. It actively cooperates with a number of universities of other countries, such as the University of International Business (Almaty, the Eurasian National University named after LN Gumilyov (Astana and the Institute of Social and Humanitarian Knowledge (Kazan.

  6. An operational utility assessment [electronic resource]: measuring the effectiveness of the Joint Concept Technology Demonstration (JCTD), Joint Forces Protection Advance Security System (JFPASS)

    OpenAIRE

    McGovern, Mark; Mayor, Jeffrey D.; Symmes, Joseph

    2008-01-01

    MBA Professional Report Planning modern military operations requires an accurate intelligence assessment of potential threats, combined with a detailed assessment of the physical theater of operations. This information can then be combined with equipment and manpower resources to set up a logistically supportable operation that mitigates as much of the enemy threat as possible. Given such a daunting challenge, military planners often turn to intelligent software agents to support their...

  7. Positive Perceptions of Access to Online Library Resources Correlates with Quality and Quantity of Scholarly Publications among Finnish Academics. A Review of: Vakkari, Pertti. “Perceived Influence of the Use of Electronic Information Resources on Scholarly Work and Publication Productivity.” Journal of the American Society for Information Science and Technology 59.4 (Feb. 15, 2008: 602-12.

    Directory of Open Access Journals (Sweden)

    Scott Marsalis

    2008-12-01

    Full Text Available Objective – To investigate the relationship between academics’ use of library electronic resources and their opinions regarding how these resources have impacted their work, and to investigate the association between this perceived influence and publication productivity during the previous two years.Design – Two specific questions added to an annual online user-survey questionnaire; additional data mined from surveySetting – Twenty-two Finnish Universities served by FinELib, the Finnish Electronic Library.Subjects – Seven hundred and sixty seven academic staff and full-time doctoral students.Methods – A questionnaire was posted in April 2007 on FinELib’s homepage and advertised on each university library’s mainpage, and focused on respondents’ experience in the previous two years. Participants selected answers either from a list of category choices, or, when measuring perceptions, by rating agreement with statements along a four-point scale. Controlled variables measured were the respondents’ academic position, their discipline, membership in a research group, whether their literature use was discipline-specific or interdisciplinary, and their perception of the availability online of the relevant core literature. The independent variable measured was the scholars’ perception of the impact of the use of electronic library resources on their work. The dependent variable measured was the scholars’ self-reported publications in the two years preceding the survey.Main Results – Participants reported a positive impact on the efficiency of their work, most strongly in areas of ease of access, with lesser impacts in the range of materials available to them and the ease with which they can keep up-to-date in their field. To a lesser extent, the scholars perceived a positive impact on the quality of their work. Upon analysis, the study found that access to online library resources improved scholars’ work by the interconnected

  8. Power Electronics

    DEFF Research Database (Denmark)

    Iov, Florin; Ciobotaru, Mihai; Blaabjerg, Frede

    2008-01-01

    is to change the electrical power production sources from the conventional, fossil (and short term) based energy sources to renewable energy resources. The other is to use high efficient power electronics in power generation, power transmission/distribution and end-user application. This paper discuss the most...... emerging renewable energy sources, wind energy, which by means of power electronics are changing from being a minor energy source to be acting as an important power source in the energy system. Power electronics is the enabling technology and the presentation will cover the development in wind turbine...... technology from kW to MW, discuss which power electronic solutions are most feasible and used today....

  9. Physiographic characterization and land use in Luiz Antônio and Santa Rita do Passa Quatro, SP, throughout the use of remote sensing and GIS

    Directory of Open Access Journals (Sweden)

    Cláudia Nagako Shida

    2012-03-01

    Full Text Available This study characterizes a region of about 82.655 ha, in Luiz Antônio and Santa Rita do Passa Quatro municipalities, SP, according to its physiography, vegetation and land uses, and identifies homogeneous landscape units which could be used for regional planning; the existence of relationships between the regional physiography and present land uses were verified. Using GIS techniques, homogeneous landscape units were identified according to physiography, land uses and native vegetation. The Chi-squaretest revealed significant associations between land uses and physiography, soil type being the most important one. Six homogeneous landscape units were identified, and in most of them, land uses were adequate according to the physiographic features. Agricultural and silvicultural activities are also present in areas of restricted use, where today's land uses should be replaced by more suitable ones.

  10. Chemical constituents in sediment in Lake Pontchartrain and in street mud and canal sediment in New Orleans, Louisiana, following Hurricanes Katrina and Rita, 2005

    Science.gov (United States)

    Van Metre, Peter C.; Wilson, Jennifer T.; Horowitz, Arthur J.; Skrobialowski, Stanley C.; Foreman, William T.; Fuller, Christopher C.; Burkhardt, Mark R.; Elrick, Kent A.; Mahler, Barbara J.; Smith, James J.; Zaugg, Steven D.

    2007-01-01

    Samples of street mud, suspended and bottom sediment in canals discharging to Lake Ponchartrain, and suspended and bottom sediment in the lake were collected and analyzed for chemical constituents to help evaluate the effects of Hurricanes Katrina and Rita and the subsequent unwatering of New Orleans, Louisiana. The approach used for sampling and analysis of chemical data for the study is presented herein. Radionuclides, major and trace elements, and numerous organic compounds in sediment were analyzed. The organic compounds include organochlorine pesticides, polychlorinated biphenyls, polycyclic aromatic hydrocarbons, urban waste indicator compounds, and current-use pesticides. Methods for the analysis of urban waste indicator compounds and current-use pesticides in sediment were developed only recently.

  11. Galls and gall makers in plants from the Pé-de-Gigante Cerrado Reserve, Santa Rita do Passa Quatro, SP, Brazil.

    Science.gov (United States)

    Urso-Guimarães, M V; Scareli-Santos, C

    2006-02-01

    Thirty-six morphologically different types of galls were obtained in leaves, leaflets, veins, petioles, stems, tendrils and flower buds from twenty-five species of plants in the Pé-de-Gigante Reserve, municipality of Santa Rita do Passa Quatro, state of São Paulo, Brazil. The host plant species belong to the closely related families Anacardiaceae, Annonaceae, Asteraceae, Bignoniaceae, Caryocaraceae, Erythroxylaceae, Fabaceae, Malpighiaceae, Melastomataceae, Myrtaceae, Ochnaceae, Polygalaceae, Sapindaceae, Sapotaceae, and Smilacaceae. The most common gall makers included Cecidomyiidae (Diptera), Pteromalidae (Hymenoptera) and Diaspididae (Sternorrhyncha-Hemiptera). This is the first report of galls found in the following plant genera: Gochnatia (Asteraceae), Distictela (Bignoniaceae), Banisteriopsis (Malpighiaceae), Ouratea (Ochnaceae), and Bredemeyera (Polygalaceae). The results of this work contribute to the body of knowledge about the relationship among host plants, gall makers, and the gall morphology of Pé-de-Gigante Cerrado Reserve.

  12. Galls and gall makers in plants from the Pé-de-Gigante Cerrado Reserve, Santa Rita do Passa Quatro, SP, Brazil

    Directory of Open Access Journals (Sweden)

    M. V. Urso-Guimarães

    Full Text Available Thirty-six morphologically different types of galls were obtained in leaves, leaflets, veins, petioles, stems, tendrils and flower buds from twenty-five species of plants in the Pé-de-Gigante Reserve, municipality of Santa Rita do Passa Quatro, state of São Paulo, Brazil. The host plant species belong to the closely related families Anacardiaceae, Annonaceae, Asteraceae, Bignoniaceae, Caryocaraceae, Erythroxylaceae, Fabaceae, Malpighiaceae, Melastomataceae, Myrtaceae, Ochnaceae, Polygalaceae, Sapindaceae, Sapotaceae, and Smilacaceae. The most common gall makers included Cecidomyiidae (Diptera, Pteromalidae (Hymenoptera and Diaspididae (Sternorrhyncha-Hemiptera. This is the first report of galls found in the following plant genera: Gochnatia (Asteraceae, Distictela (Bignoniaceae, Banisteriopsis (Malpighiaceae, Ouratea (Ochnaceae, and Bredemeyera (Polygalaceae. The results of this work contribute to the body of knowledge about the relationship among host plants, gall makers, and the gall morphology of Pé-de-Gigante Cerrado Reserve.

  13. Disaster-related exposures and health effects among US Coast Guard responders to Hurricanes Katrina and Rita: a cross-sectional study.

    Science.gov (United States)

    Rusiecki, Jennifer A; Thomas, Dana L; Chen, Ligong; Funk, Renée; McKibben, Jodi; Dayton, Melburn R

    2014-08-01

    Disaster responders work among poorly characterized physical and psychological hazards with little understood regarding health consequences of their work. A survey administered to 2834 US Coast Guard responders to Hurricanes Katrina and Rita provided data on exposures and health effects. Prevalence odds ratios (PORs) evaluated associations between baseline characteristics, missions, exposures, and health effects. Most frequent exposures were animal/insect vector (n = 1309; 46%) and floodwater (n = 817; 29%). Most frequent health effects were sunburn (n = 1119; 39%) and heat stress (n = 810; 30%). Significant positive associations were for mold exposure and sinus infection (POR = 10.39); carbon monoxide and confusion (POR = 6.27); lack of sleep and slips, trips, falls (POR = 3.34) and depression (POR = 3.01); being a Gulf-state responder and depression (POR = 3.22). Increasing protection for disaster responders requires provisions for adequate sleep, personal protective equipment, and access to medical and psychological support.

  14. Mapping the spatial and temporal dynamics of the velvet mesquite with MODIS and AVIRIS: Case study at the Santa Rita Experimental Range

    Science.gov (United States)

    Kaurivi, Jorry Zebby Ujama

    The general objective of this research is to develop a methodology that will allow mapping and quantifying shrub encroachment with remote sensing. The multitemporal properties of the Moderate Resolution Imaging Spectroradiometer (MODIS) -250m, 16-day vegetation index products were combined with the hyperspectral and high spatial resolution (3.6m) computation of the Airborne Visible-Infrared Imaging Spectrometer (AVIRIS) to detect the dynamics of mesquite and grass/soil matrix at two sites of high (19.5%) and low (5.7%) mesquite cover in the Santa Rita Experimental Range (SRER). MODIS results showed separability between grassland and mesquite based on phenology. Mesquite landscapes had longer green peak starting in April through February, while the grassland only peaked during the monsoon season (July through October). AVIRIS revealed spectral separability, but high variation in the data implicated high heterogeneity in the landscape. Nonetheless, the methodology for larger data was developed in this study and combines ground, air and satellite data.

  15. Merge of terminological resources

    DEFF Research Database (Denmark)

    Henriksen, Lina; Braasch, Anna

    2012-01-01

    In our globalized world, the amount of cross-national communication increases rapidly, which also calls for easy access to multi-lingual high quality terminological resources. Sharing of terminology resources is currently becoming common practice, and efficient strategies for integration...... – or merging – of terminology resources are strongly needed. This paper discusses prerequisites for successful merging with the focus on identification of candidate duplicates of a subject domain found in the resources to be merged, and it describes automatic merging strategies to be applied to such duplicates...... in electronic terminology resources. Further, some perspectives of manual, supplementary assessment methods supporting the automatic procedures are sketched. Our considerations are primarily based on experience gained in the IATE and EuroTermBank projects, as merging was a much discussed issue in both projects....

  16. Renewable energy resources

    DEFF Research Database (Denmark)

    Ellabban, Omar S.; Abu-Rub, Haitham A.; Blaabjerg, Frede

    2014-01-01

    Electric energy security is essential, yet the high cost and limited sources of fossil fuels, in addition to the need to reduce greenhouse gasses emission, have made renewable resources attractive in world energy-based economies. The potential for renewable energy resources is enormous because...... they can, in principle, exponentially exceed the world's energy demand; therefore, these types of resources will have a significant share in the future global energy portfolio, much of which is now concentrating on advancing their pool of renewable energy resources. Accordingly, this paper presents how...... renewable energy resources are currently being used, scientific developments to improve their use, their future prospects, and their deployment. Additionally, the paper represents the impact of power electronics and smart grid technologies that can enable the proportionate share of renewable energy...

  17. Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX

    Science.gov (United States)

    Spinnler, C; Hedström, E; Li, H; de Lange, J; Nikulenkov, F; Teunisse, A F A S; Verlaan-de Vries, M; Grinkevich, V; Jochemsen, A G; Selivanova, G

    2011-01-01

    Inactivation of the p53 tumour suppressor, either by mutation or by overexpression of its inhibitors Hdm2 and HdmX is the most frequent event in cancer. Reactivation of p53 by targeting Hdm2 and HdmX is therefore a promising strategy for therapy. However, Hdm2 inhibitors do not prevent inhibition of p53 by HdmX, which impedes p53-mediated apoptosis. Here, we show that p53 reactivation by the small molecule RITA leads to efficient HdmX degradation in tumour cell lines of different origin and in xenograft tumours in vivo. Notably, HdmX degradation occurs selectively in cancer cells, but not in non-transformed cells. We identified the inhibition of the wild-type p53-induced phosphatase 1 (Wip1) as the major mechanism important for full engagement of p53 activity accomplished by restoration of the ataxia telangiectasia mutated (ATM) kinase-signalling cascade, which leads to HdmX degradation. In contrast to previously reported transactivation of Wip1 by p53, we observed p53-dependent repression of Wip1 expression, which disrupts the negative feedback loop conferred by Wip1. Our study reveals that the depletion of both HdmX and Wip1 potentiates cell death due to sustained activation of p53. Thus, RITA is an example of a p53-reactivating drug that not only blocks Hdm2, but also inhibits two important negative regulators of p53 – HdmX and Wip1, leading to efficient elimination of tumour cells. PMID:21546907

  18. Multicenter Phase II Study with Weekly Bendamustine and Paclitaxel as First- or Later-Line Therapy in Patients with Metastatic Breast Cancer: RiTa II Trial.

    Science.gov (United States)

    Loibl, Sibylle; Doering, Gabriele; Müller, Lothar; Grote-Metke, Albert; Müller, Roberto; Tomé, Oliver; Wiest, Wolfgang; Maisch, Andrea; Nekljudova, Valentina; von Minckwitz, Gunter

    2011-12-01

    The combination of bendamustine (B) and paclitaxel (P) as anthracycline-free treatment option in patients with advanced breast cancer has been evaluated in the previous RiTa I trial. The regimen of weekly B 70 mg/m(2) and P 90 mg/m(2) with a pause every 4th week was established as an effective regimen with low toxicity. The aim of the present RiTa II study was to investigate the potential of BP as anthracycline-free combination therapy. The primary objective was to determine the progression-free survival (PFS); secondary endpoints were safety, tolerability, overall response rate (ORR) and overall survival (OS). 26 patients were available, 15 received BP as first-line, 11 as beyond first-line treatment. 27% patients had triple-negative breast cancer (TNBC). Median PFS and OS were 7.3 months (95% confidence interval (CI): 5.5-10.9) and 14.9 months (95% CI: 9.9-22.9), respectively. The 1-year PFS rate was 20.3% and the 1-year OS rate 71.2%. The ORR was 42.3%, including 4 complete and 7 partial remissions. TNBC patients reached an ORR of 71.4%. Anthracycline-pretreated patients showed an ORR of 43.8%, confirming bendamustine's lack of cross-resistance to anthracycline agents. BP represents a favorable option with moderate toxicity in pretreated metastatic breast cancer and offers a possibility for application in anthracycline-pretreated and TNBC patients.

  19. Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX.

    Science.gov (United States)

    Spinnler, C; Hedström, E; Li, H; de Lange, J; Nikulenkov, F; Teunisse, A F A S; Verlaan-de Vries, M; Grinkevich, V; Jochemsen, A G; Selivanova, G

    2011-11-01

    Inactivation of the p53 tumour suppressor, either by mutation or by overexpression of its inhibitors Hdm2 and HdmX is the most frequent event in cancer. Reactivation of p53 by targeting Hdm2 and HdmX is therefore a promising strategy for therapy. However, Hdm2 inhibitors do not prevent inhibition of p53 by HdmX, which impedes p53-mediated apoptosis. Here, we show that p53 reactivation by the small molecule RITA leads to efficient HdmX degradation in tumour cell lines of different origin and in xenograft tumours in vivo. Notably, HdmX degradation occurs selectively in cancer cells, but not in non-transformed cells. We identified the inhibition of the wild-type p53-induced phosphatase 1 (Wip1) as the major mechanism important for full engagement of p53 activity accomplished by restoration of the ataxia telangiectasia mutated (ATM) kinase-signalling cascade, which leads to HdmX degradation. In contrast to previously reported transactivation of Wip1 by p53, we observed p53-dependent repression of Wip1 expression, which disrupts the negative feedback loop conferred by Wip1. Our study reveals that the depletion of both HdmX and Wip1 potentiates cell death due to sustained activation of p53. Thus, RITA is an example of a p53-reactivating drug that not only blocks Hdm2, but also inhibits two important negative regulators of p53 - HdmX and Wip1, leading to efficient elimination of tumour cells.

  20. EFFECTIVE ELECTRONIC TUTORIAL

    Directory of Open Access Journals (Sweden)

    Andrei A. Fedoseev

    2014-01-01

    Full Text Available The article analyzes effective electronic tutorials creation and application based on the theory of pedagogy. Herewith the issues of necessary electronic tutorial functional, ways of the educational process organization with the use of information and communication technologies and the logistics of electronic educational resources are touched upon. 

  1. Resistência de Biomphalaria peregrina de Santa Rita do Sapucaí, Minas Gerais, a infecção com três cepas de Schistosoma mansoni Resistance of Biomphalaria peregrina from Santa Rita do Sapucaí, State of Minas Gerais, Brazil, to infection with strain of Schistosoma mansoni

    Directory of Open Access Journals (Sweden)

    Cecília Pereira de Souza

    1988-12-01

    Full Text Available Descendentes do planorbídeo Biomphalaria peregrina, coletados em Santa Rita do Sapucaí, Minas Gerais, Brasil, foram expostos a miracídios de três cepas de Schistosoma mansoni: "LE" de Belo Horizonte, MG; "SJ" de São José dos Campos, SP e "AL" do Estado de Alagoas. Dentre 300 exemplares expostos, nenhum se infectou com as três cepas do trematódeo. Por outro lado, 300 exemplares de B. glabrata, dos grupos de controle, apresentaram taxas de infecção de 61,1 a 95,3% com as três cepas do trematódeo. As taxas de mortalidade de B. peregrina e de B. glabrata foram de 20,0 e de 28,0%, respectivamente.The descendants of the planorbid snail Biomphalaria peregrina, collected in the region of Santa rita do Sapucaí, Minas Gerais, Brazil, were exposed to miracidia of three strains of Schistosoma mansoni: "LE" strain from Belo Horizonte, State of Minas Gerais; "SJ", strain from São José dos Campos, State of São Paulo and "AL" strain from State of Alagoas. Of 300 snails exposed to miracidia of the three strains, none was infected. On the other hand, 300 Biomphalaria glabrata of the control groups showed infection rates of 61.1 to 95.3% with three strains. The mortality rates of B. peregrina and B. glabrata were 20% and 28%, respectively.

  2. Centre cultural Santa Rita

    OpenAIRE

    Boixet Méndez, Oriol; Martín Casado, Sara; Mas Muñoz, Mireia; Montoya Martínez, Jose Ramón; Serena López, Álex; Vera Benjauma, Mercedes

    2013-01-01

    Situada en la comuna de Pelarco, la edificación consta de una superficie construida de 4.295 metros cuadrados. Dividida en 2 patios interiores y diferentes alas, se encuentra en una extensa superficie de terreno. La construcción original está formada por muros de adobe, pilares con base de piedra, fuste y capitel de madera, una techumbre compuesta por cerchas de madera en forma tradicional chilena conocida como tijeral, cubierta, también tradicional, de tejas cerámicas a cuatro ag...

  3. Drug resistance to inhibitors of the human double minute-2 E3 ligase is mediated by point mutations of p53, but can be overcome with the p53 targeting agent RITA.

    Science.gov (United States)

    Jones, Richard J; Bjorklund, Chad C; Baladandayuthapani, Veerabhadran; Kuhn, Deborah J; Orlowski, Robert Z

    2012-10-01

    The human double minute (HDM)-2 E3 ubiquitin ligase plays a key role in p53 turnover and has been validated preclinically as a target in multiple myeloma (MM) and mantle cell lymphoma (MCL). HDM-2 inhibitors are entering clinical trials, and we therefore sought to understand potential mechanisms of resistance in lymphoid models. Wild-type p53 H929 MM and Granta-519 MCL cells resistant to MI-63 or Nutlin were generated by exposing them to increasing drug concentrations. MI-63-resistant H929 and Granta-519 cells were resistant to Nutlin, whereas Nutlin-resistant cells displayed cross-resistance to MI-63. These cells also showed cross-resistance to bortezomib, doxorubicin, cisplatin, and melphalan, but remained sensitive to the small molecule inhibitor RITA (reactivation of p53 and induction of tumor cell apoptosis). HDM-2 inhibitor-resistant cells harbored increased p53 levels, but neither genotoxic nor nongenotoxic approaches to activate p53 induced HDM-2 or p21. Resequencing revealed wild-type HDM-2, but mutations were found in the p53 DNA binding and dimerization domains. In resistant cells, RITA induced a G(2)-M arrest, upregulation of p53 targets HDM-2, PUMA, and NOXA, and PARP cleavage. Combination regimens with RITA and MI-63 resulted in enhanced cell death compared with RITA alone. These findings support the possibility that p53 mutation could be a primary mechanism of acquired resistance to HDM-2 inhibitors in MCL and MM. Furthermore, they suggest that simultaneous restoration of p53 function and HDM-2 inhibition is a rational strategy for clinical translation.

  4. A review of the incidence and coincidence of uterine and mammary tumors in Wistar and Sprague-Dawley rats based on the RITA database and the role of prolactin.

    Science.gov (United States)

    Harleman, Johannes H; Hargreaves, Adam; Andersson, Håkan; Kirk, Sarah

    2012-08-01

    Wistar rats are frequently selected for use in carcinogenicity studies because of their advantageous survival rate, which is more favorable than other strains such as the Sprague-Dawley (SD) strain. Uterine and mammary tumors are relatively common spontaneous neoplasms of both strains. We examined the incidence and coincidence of uterine tumors and mammary tumors in control animals of both strains within the RITA database. There was a strong inverse relationship between these tumor types in Wistar rats (p 10%.

  5. Real-world health outcomes in adults with moderate-to-severe psoriasis in the United States: a population study using electronic health records to examine patient-perceived treatment effectiveness, medication use, and healthcare resource utilization.

    Science.gov (United States)

    Armstrong, April W; Foster, Shonda A; Comer, Brian S; Lin, Chen-Yen; Malatestinic, William; Burge, Russel; Goldblum, Orin

    2018-06-28

    Little is known regarding real-world health outcomes data among US psoriasis patients, but electronic health records (EHR) that collect structured data at point-of-care may provide opportunities to investigate real-world health outcomes among psoriasis patients. Our objective was to investigate patient-perceived treatment effectiveness, patterns of medication use (duration, switching, and/or discontinuation), healthcare resource utilization, and medication costs using real-world data from psoriasis patients. Data for adults (≥18-years) with a dermatology provider-given diagnosis of psoriasis from 9/2014-9/2015 were obtained from dermatology practices using a widely used US dermatology-specific EHR containing over 500,000 psoriasis patients. Disease severity was captured by static physician's global assessment and body surface area. Patient-perceived treatment effectiveness was assessed by a pre-defined question. Treatment switching and duration were documented. Reasons for discontinuations were assessed using pre-defined selections. Healthcare resource utilization was defined by visit frequency and complexity. From 82,621 patients with psoriasis during the study period, patient-perceived treatment effectiveness was investigated in 2200 patients. The proportion of patients reporting "strongly agree" when asked if their treatment was effective was highest for biologics (73%) and those reporting treatment adherence (55%). In 16,000 patients who received oral systemics and 21,087 patients who received biologics, median treatment duration was longer for those who received biologics (160 vs. 113 days, respectively). Treatment switching was less frequent among patients on systemic monotherapies compared to those on combination therapies. The most common reason for discontinuing biologics was loss of efficacy; the most common reason for discontinuing orals was side effects. In 28,754 patients, higher disease severity was associated with increased healthcare resource

  6. Water Resources

    International Nuclear Information System (INIS)

    Abira, M.A.

    1997-01-01

    Water is essential for life and ecological sustenance; its availability is essential component of national welfare and productivity.The country's socio-economic activities are largely dependent on the natural endowment of water resources. Kenya's water resources comprises of surface waters (rivers, lakes and wetlands) and ground water. Surface water forms 86% of total water resources while the rest is ground water Geological, topographical and climatic factors influence the natural availability and distribution of water with the rainfall distribution having the major influence. Water resources in Kenya are continuously under threat of depletion and quality degradation owing to rising population, industrialization, changing land use and settlement activities as well as natural changes. However, the anticipated climate change is likely to exacerbate the situation resulting in increased conflict over water use rights in particular, and, natural resource utilisation in general. The impacts of climate change on the water resources would lead to other impacts on environmental and socio-economic systems

  7. A Cáritas brasileira e a Economia Popular Solidária: O Agente de Cáritas e a Caridade Libertadora (Brazilian Caritas and the Popular Solidarity Economy: The Agent of Caritas and the Charity Liberating - DOI: 10.5752/P.2175-5841.2013v11n32p1506

    Directory of Open Access Journals (Sweden)

    Joannes Paulus Silva Forte

    2013-12-01

    Full Text Available O presente artigo analisa as ligações entre a Cáritas Brasileira e a Economia Popular Solidária a partir do trabalho do Agente de Cáritas. A problemática central do artigo remete às representações sociais que esses Agentes constroem em seus relatos sobre os princípios da Teologia da Libertação que norteiam os projetos em economia solidária da referida instituição religiosa. A metodologia de base qualitativa e etnográfica consistiu na realização da revisão bibliográfica, consulta a materiais institucionais, observação in loco e entrevistas semiestruturadas com Agentes que atuam na Economia Popular Solidária no estado do Ceará. A análise das representações sinaliza que a própria noção de “Reino de Deus” na terra pressupõe a vinculação profunda entre religião e economia, mística e movimentos sociais, religião e Estado, configurando, dessa forma, um projeto de sociedade contra hegemônico que se vislumbra mediante a transformação radical da base econômica e moral do tecido social contrapondo individualismo à solidariedade. Palavras-chave: Cáritas Brasileira. Economia Popular Solidária. Caridade Libertadora. Teologia da Libertação.  Abstract This article examines the links between Brazilian Caritas and Popular Solidarity Economy from the work of Caritas Agent. The central issue of the article refers to the social representations that these agents build in his histories about the principles of Liberation Theology that guide the projects in solidarity economy of that religious institution. The basic methodology used was qualitative and ethnographic; It consisted in literature review, consultation to institutional materials, observation in loco and semi-structured interviews with agents who act in the Popular Solidarity Economy in the state of Ceará. The analysis of representations indicates that the very notion of "Kingdom of God" on earth presupposes deep linking between religion and economics, mystic

  8. A REESTRUTURAÇÃO PRODUTIVA E O CIRCUITO INFERIOR DO TURISMO NAS PRAIAS DE REDINHA NOVA, SANTA RITA E JENIPABU, EXTREMOZ – RN

    Directory of Open Access Journals (Sweden)

    José Alexandre Berto de Almada

    2017-03-01

    Cette étude vise à analyser le processus de restructuration productive du tourisme à Rio Grande do Norte du territoire utilisée par le circuit inférieur du tourisme sur les plages appartenant à APAJ, Redinha Nova, Santa Rita et Jenipabu dans la municipalité de Extremoz, afin de comprendre la relation dialectique de l'interdépendance entre dépendante circuit inférieur du tourisme dans ces plages et le circuit supérieur fait du tourisme dans la Via Costeira et plage de Ponta Negra à Natal. L'analyse du circuit inférieur a été réalisée à partir du travail de terrain, effectué entre Janvier et Juin 2014 dans l’APAJ, qui a interviewé presque tous les commerçants locaux, à l'exception des dix entreprises ou des commerçants fermés qui ont refusé de participer à l'entrevue, totalisant quatre-vingt dix six établissements visités. Au cours du travail sur le terrain, nous avons également recueilli des données cartographiques via l'unité GPS dans laquelle ils ont été utilisés dans la préparation des cartes de répartition spatiale de l'urbanisation et territoire utilisés par le circuit inférieur dans l’APAJ. Lors de la visite de la ville de NatalLes touristes ne sont pas seulement dans cette ville. Il existe une variété de lieux à visiter, à la fois sur la côte nord et la côte sud de Rio Grande do Norte. L'un de ces lieux sont les plages de l’APAJ, Redinha Nova, Santa Rita et Jenipabu où le processus d'urbanisation dans la Via Costeira et Ponta Negra rendu possible la mise en place du circuit touristique inférieur cette apa. L'afflux de touristes à ces plages apporte avec elle un discours de développement économique pour le lieu et pour les habitants. La contradiction entre les deux circuits est plus mauvais pour ceux qui sont sur le côté inférieur de l'économie. Alors que les entreprises du circuit supérieur visent l'accumulation de capital ainsi que les dividendes peuvent être utilisés dans de nouveaux

  9. Electronics and electronic systems

    CERN Document Server

    Olsen, George H

    1987-01-01

    Electronics and Electronic Systems explores the significant developments in the field of electronics and electronic devices. This book is organized into three parts encompassing 11 chapters that discuss the fundamental circuit theory and the principles of analog and digital electronics. This book deals first with the passive components of electronic systems, such as resistors, capacitors, and inductors. These topics are followed by a discussion on the analysis of electronic circuits, which involves three ways, namely, the actual circuit, graphical techniques, and rule of thumb. The remaining p

  10. Uranium resources

    International Nuclear Information System (INIS)

    Gangloff, A.

    1978-01-01

    It is first indicated how to evaluate the mining resources as a function of the cost of production and the degree of certainty in the knowledge of the deposit. A table is given of the world resources (at the beginning 1977) and resources and reserves are compared. There is a concordance between requirements and possible production until 1990. The case of France is examined: known reserves, present and future prospection, present production (In 1978 2200 T of U metal will be produced from 3 French processing plants), production coming from Cogema. A total production of 2000 T in 1980 and 10.000 in 1985 is expected [fr

  11. Seaweed resources

    Digital Repository Service at National Institute of Oceanography (India)

    Deshmukhe, G.V.; Dhargalkar, V.K.; Untawale, A.G.

    The chapter summarizes our present knowledge of the seaweed resources of the Indian Ocean region with regard to the phytogeographical distribution, composition, biomass, utilization, cultivation, conservation and management. The voluminous data...

  12. Arthritis - resources

    Science.gov (United States)

    Resources - arthritis ... The following organizations provide more information on arthritis : American Academy of Orthopaedic Surgeons -- orthoinfo.aaos.org/menus/arthritis.cfm Arthritis Foundation -- www.arthritis.org Centers for Disease Control and Prevention -- www. ...

  13. Mineral resources

    Digital Repository Service at National Institute of Oceanography (India)

    Valsangkar, A.B.

    (placers), biogenous (ooze, limestone) or chemogenous (phosphorites and polymetallic nodules) type. In recent years, hydrothermal deposits, cobalt crust and methane gas hydrates are considered as frontier resources. Their distribution depends upon proximity...

  14. Depression - resources

    Science.gov (United States)

    Resources - depression ... Depression is a medical condition. If you think you may be depressed, see a health care provider. ... following organizations are good sources of information on depression : American Psychological Association -- www.apa.org/topics/depression/ ...

  15. Hemophilia - resources

    Science.gov (United States)

    Resources - hemophilia ... The following organizations provide further information on hemophilia : Centers for Disease Control and Prevention -- www.cdc.gov/ncbddd/hemophilia/index.html National Heart, Lung, and Blood Institute -- www.nhlbi.nih.gov/ ...

  16. Diabetes - resources

    Science.gov (United States)

    Resources - diabetes ... The following sites provide further information on diabetes: American Diabetes Association -- www.diabetes.org Juvenile Diabetes Research Foundation International -- www.jdrf.org National Center for Chronic Disease Prevention and Health Promotion -- ...

  17. Forest Resources

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-06-01

    Forest biomass is an abundant biomass feedstock that complements the conventional forest use of wood for paper and wood materials. It may be utilized for bioenergy production, such as heat and electricity, as well as for biofuels and a variety of bioproducts, such as industrial chemicals, textiles, and other renewable materials. The resources within the 2016 Billion-Ton Report include primary forest resources, which are taken directly from timberland-only forests, removed from the land, and taken to the roadside.

  18. New Orleans before and after Hurricanes Katrina/Rita: a quasi-experiment of the association between soil lead and children's blood lead.

    Science.gov (United States)

    Zahran, Sammy; Mielke, Howard W; Gonzales, Christopher R; Powell, Eric T; Weiler, Stephan

    2010-06-15

    Prior to Hurricanes Katrina and Rita (HKR), significant associations were noted between soil lead (SL) and blood lead (BL) in New Orleans. Engineering failure of New Orleans levees and canal walls after HKR set the stage for a quasi-experiment to evaluate BL responses by 13 306 children to reductions in SL. High density soil surveying conducted in 46 census tracts before HKR was repeated after the flood. Paired t test results show that SL decreased from 328.54 to 203.33 mg/kg post-HKR (t = 3.296, p or =50% decrease in SL. Also individual BL in children was predicted as a function of SL, adjusting for age, year of observation, and depth of flood waters. At the individual scale, BL decreased significantly in post-HKR as a function of SL, with BL decreases ranging from b = -1.20 to -1.65 microg/dL, depending on the decline of SL and whether children were born in the post-HKR period. Our results support policy to improve soil conditions for children.

  19. Florística em um hectare de cerrado stricto sensu na ARIE - cerrado Pé-de-Gigante, Santa Rita do Passa Quatro, SP

    Directory of Open Access Journals (Sweden)

    Weiser Veridiana de Lara

    2001-01-01

    Full Text Available Foi realizado um levantamento florístico em um ha de cerrado stricto sensu, na parte norte da ARIE - Cerrado Pé-de-Gigante, Santa Rita do Passa Quatro, São Paulo. Foram coletados 428 espécimes em fase reprodutiva, em vinte e cinco excursões de coleta, durante o período de novembro de 1996 a abril de 1998. A listagem florística obtida apresenta 141 espécies, distribuídas em 109 gêneros e 49 famílias. As famílias mais representativas foram: Leguminosae, Asteraceae, Malpighiaceae e Myrtaceae. A floração e frutificação das espécies foram maiores no período chuvoso. Espécies zoocóricas (61 predominaram, seguidas pelas anemocóricas (46 e autocóricas (34. Analisou-se a flora como um todo e seus componentes herbáceo-subarbustivo e arbustivo-arbóreo, separadamente.

  20. Riems influenza a typing array (RITA): An RT-qPCR-based low density array for subtyping avian and mammalian influenza a viruses.

    Science.gov (United States)

    Hoffmann, Bernd; Hoffmann, Donata; Henritzi, Dinah; Beer, Martin; Harder, Timm C

    2016-06-03

    Rapid and sensitive diagnostic approaches are of the utmost importance for the detection of humans and animals infected by specific influenza virus subtype(s). Cascade-like diagnostics starting with the use of pan-influenza assays and subsequent subtyping devices are normally used. Here, we demonstrated a novel low density array combining 32 TaqMan(®) real-time RT-PCR systems in parallel for the specific detection of the haemagglutinin (HA) and neuraminidase (NA) subtypes of avian and porcine hosts. The sensitivity of the newly developed system was compared with that of the pan-influenza assay, and the specificity of all RT-qPCRs was examined using a broad panel of 404 different influenza A virus isolates representing 45 different subtypes. Furthermore, we analysed the performance of the RT-qPCR assays with diagnostic samples obtained from wild birds and swine. Due to the open format of the array, adaptations to detect newly emerging influenza A virus strains can easily be integrated. The RITA array represents a competitive, fast and sensitive subtyping tool that requires neither new machinery nor additional training of staff in a lab where RT-qPCR is already established.

  1. Teaching Resources

    Science.gov (United States)

    Physics?" Poster Pamphlets/Books/SPIN-UP Resources Making and Sustaining Changes in Undergraduate AAPT.org - American Association of Physics Teachers Skip to content Skip to navigation Skip to local navigation AAPT - American Association of Physics Teachers Go Sign In / Online Services Join

  2. Resource Mobilization

    International Development Research Centre (IDRC) Digital Library (Canada)

    constitute endorsement of the product and is given only for information. ..... point where they could significantly impact an organization's financial viability. This alternative ... putting in place internal systems and processes that enable the resource .... control over the incorporation of non-profit organizations. ..... Accounting.

  3. Resource Mobilization

    International Development Research Centre (IDRC) Digital Library (Canada)

    Annex 1: The Scoping Study on Donor Funding for. Development Research in ... publication of the Resource Mobilization: A Practical Guide for Research .... applied the concept or technique, which validates the practical application of ... some other staff member would write up a grant application addressed to one, two, or a ...

  4. Superfund oversight. Hearing before the Committee on Environment and Public Works, United States Senate, Ninety-Eighth Congress, First Session to receive testimony from Rita M. Lavelle, February 23, 1983. Part 1

    Energy Technology Data Exchange (ETDEWEB)

    1983-01-01

    Part 1 of the hearing record covers the testimony of Rita M. Lavelle, former Assistant Administrator for Solid Waste and Emergency Response of the Environmental Protection Agency (EPA). Lavelle was asked to respond to charges against her performance and to describe how policy decisions are made at the agency. At issue were criticisms that EPA administrators were obstructing the implementation of environmental laws. Lavelle accused critics of undermining the agency's effectiveness and credibility in their handling of her departure from EPA, and responded to questions on her relationships with agency personnel. (DCK)

  5. Chemical dependence - resources

    Science.gov (United States)

    Substance use - resources, Drug abuse - resources; Resources - chemical dependence ... are a good resource for information on drug dependence: National Council on Alcoholism and Drug Dependence -- ncadd. ...

  6. Algae Resources

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-06-01

    Algae are highly efficient at producing biomass, and they can be found all over the planet. Many use sunlight and nutrients to create biomass, which contain key components—including lipids, proteins, and carbohydrates— that can be converted and upgraded to a variety of biofuels and products. A functional algal biofuels production system requires resources such as suitable land and climate, sustainable management of water resources, a supplemental carbon dioxide (CO2) supply, and other nutrients (e.g., nitrogen and phosphorus). Algae can be an attractive feedstock for many locations in the United States because their diversity allows for highpotential biomass yields in a variety of climates and environments. Depending on the strain, algae can grow by using fresh, saline, or brackish water from surface water sources, groundwater, or seawater. Additionally, they can grow in water from second-use sources such as treated industrial wastewater; municipal, agricultural, or aquaculture wastewater; or produced water generated from oil and gas drilling operations.

  7. Uranium resources

    International Nuclear Information System (INIS)

    1976-01-01

    This is a press release issued by the OECD on 9th March 1976. It is stated that the steep increases in demand for uranium foreseen in and beyond the 1980's, with doubling times of the order of six to seven years, will inevitably create formidable problems for the industry. Further substantial efforts will be needed in prospecting for new uranium reserves. Information is given in tabular or graphical form on the following: reasonably assured resources, country by country; uranium production capacities, country by country; world nuclear power growth; world annual uranium requirements; world annual separative requirements; world annual light water reactor fuel reprocessing requirements; distribution of reactor types (LWR, SGHWR, AGR, HWR, HJR, GG, FBR); and world fuel cycle capital requirements. The information is based on the latest report on Uranium Resources Production and Demand, jointly issued by the OECD's Nuclear Energy Agency (NEA) and the International Atomic Energy Agency. (U.K.)

  8. Toxic trace element assessment for soils/sediments deposited during Hurricanes Katrina and Rita from southern Louisiana, USA: a sequential extraction analysis.

    Science.gov (United States)

    Shi, Honglan; Witt, Emitt C; Shu, Shi; Su, Tingzhi; Wang, Jianmin; Adams, Craig

    2010-07-01

    Analysis of soil/sediment samples collected in the southern Louisiana, USA, region three weeks after Hurricanes Katrina and Rita passed was performed using sequential extraction procedures to determine the origin, mode of occurrence, biological availability, mobilization, and transport of trace elements in the environment. Five fractions: exchangeable, bound to carbonates, bound to iron (Fe)-manganese (Mn) oxides, bound to organic matter, and residual, were subsequently extracted. The toxic trace elements Pb, As, V, Cr, Cu, and Cd were analyzed in each fraction, together with Fe in 51 soil/sediment samples. Results indicated that Pb and As were at relatively high concentrations in many of the soil/sediment samples. Because the forms in which Pb and As are present tend to be highly mobile under naturally occurring environmental conditions, these two compounds pose an increased health concern.Vanadium and Cr were mostly associated with the crystal line nonmobile residual fraction. A large portion of the Cu was associated with organic matter and residual fraction. Cadmium concentrations were low in all soil/sediment samples analyzed and most of this element tended to be associated with the mobile fractions. An average of 21% of the Fe was found in the Fe-Mn oxide fraction, indicating that a substantial part of the Fe was in an oxidized form. The significance of the overall finding of the present study indicated that the high concentrations and high availabilities of the potentially toxic trace elements As and Pb may impact the environment and human health in southern Louisiana and, in particular, the New Orleans area. Copyright (c) 2010 SETAC.

  9. Calidad microbiológica y parasitológica de lechuga (Lactuca sativa y cilantro (Coriandrum sativum expendidos en la Parroquia Santa Rita, Aragua, Venezuela

    Directory of Open Access Journals (Sweden)

    Nirza Noguera Machado

    2016-10-01

    Full Text Available Las hortalizas aportan grandes beneficios para la salud debido a sus innumerables propiedades alimenticias; sin embargo, existe una gran variedad de factores que ponen en riesgo la calidad sanitaria de las mismas constituyéndose en vehículos para enfermedades de transmisión alimentaria (ETA. Por ello, se decidió evaluar la calidad microbiológica y parasitológica de dos hortalizas, lechuga (Lactuca sativa y cilantro (Coriandrum sativum expendidas en la Parroquia Santa Rita del Municipio Francisco Linares Alcántara (Aragua, Venezuela. Se analizaron un total de 20 muestras, 10 de cilantro y 10 de lechuga; la determinación microbiológica se realizó por la técnica del Número Más Probable y el análisis parasitológico, mediante observación directa, tinción de Kinyoun y la técnica de Faust. Los resultados mostraron la presencia de coliformes totales (1,1x104 NMP/g en el 100 % de las muestras. No se evidenció coliformes fecales en ninguna de las muestras. En relación al análisis parasitológico, se identificaron protozoarios intestinales, con mayor prevalencia de Blastocystis spp. y menor en helmintos. Los resultados demuestran el peligro potencial que representa el consumo de hortalizas frescas contaminadas para la salud pública. Se debe concientizar a la población sobre medidas sanitarias preventivas que deben aplicar antes del consumo e implementar medidas de control que mejoren las condiciones higiénicas en la cadena de comercialización.

  10. Looking for the Silver Lining: Benefit Finding after Hurricanes Katrina and Rita in Middle-Aged, Older, and Oldest-Old Adults.

    Science.gov (United States)

    Stanko, Katie E; Cherry, Katie E; Ryker, Kyle S; Mughal, Farra; Marks, Loren D; Brown, Jennifer Silva; Gendusa, Patricia F; Sullivan, Marisa C; Bruner, John; Welsh, David A; Su, L Joseph; Jazwinski, S Michal

    2015-09-01

    Looking for potentially positive outcomes is one way that people cope with stressful events. In two studies, we examined perceived "silver linings" after the 2005 Hurricanes Katrina and Rita among indirectly affected adults. In Study 1, middle-aged (ages 47-64 years), older (ages 65-89 years), and oldest-old (ages 90-95 years) adults in the Louisiana Healthy Aging Study (LHAS) responded to an open-ended question on perceived silver linings in a longitudinal assessment carried out during the immediate impact (1 to 4 months after landfall) and post-disaster recovery phase (6 to 14 months post-storm). Qualitative grounded theory methods were employed to analyze these narrative data. Team-based coding yielded three core themes: (1) learning experience and better preparedness for future disasters, (2) having improved cities (Baton Rouge and New Orleans), and (3) an increase in "Good Samaritan" acts such as strangers helping one another. Responses were similar across age groups, although older adults were the least likely to report positive outcomes. Study 2 was a conceptual replication using a different sample of adults (ages 31 to 82 years) tested at least five years after the storms. A learning experience and preparedness core theme replicated Study 1's findings while improved social cohesion amongst family and friends emerged as a new core theme in Study 2. These data indicate that identifying lessons learned and potentially positive outcomes are psychological reactions that may facilitate post-disaster coping and foster resilience for indirectly affected adults in the years after disaster.

  11. Relativistically Induced Transparency Acceleration (RITA) - laser-plasma accelerated quasi-monoenergetic GeV ion-beams with existing lasers?

    Science.gov (United States)

    Sahai, Aakash A.

    2013-10-01

    Laser-plasma ion accelerators have the potential to produce beams with unprecedented characteristics of ultra-short bunch lengths (100s of fs) and high bunch-charge (1010 particles) over acceleration length of about 100 microns. However, creating and controlling mono-energetic bunches while accelerating to high-energies has been a challenge. If high-energy mono-energetic beams can be demonstrated with minimal post-processing, laser (ω0)-plasma (ωpe) ion accelerators may be used in a wide-range of applications such as cancer hadron-therapy, medical isotope production, neutron generation, radiography and high-energy density science. Here we demonstrate using analysis and simulations that using relativistic intensity laser-pulses and heavy-ion (Mi ×me) targets doped with a proton (or light-ion) species (mp ×me) of trace density (at least an order of magnitude below the cold critical density) we can scale up the energy of quasi-mono-energetically accelerated proton (or light-ion) beams while controlling their energy, charge and energy spectrum. This is achieved by controlling the laser propagation into an overdense (ω0 RITA). Desired proton or light-ion energies can be achieved by controlling the velocity of the snowplow, which is shown to scale inversely with the rise-time of the laser (higher energies for shorter pulses) and directly with the scale-length of the plasma density gradient. Similar acceleration can be produced by controlling the increase of the laser frequency (Chirp Induced Transparency Acceleration, ChITA). Work supported by the National Science Foundation under NSF- PHY-0936278. Also, NSF-PHY-0936266 and NSF-PHY-0903039; the US Department of Energy under DEFC02-07ER41500, DE- FG02-92ER40727 and DE-FG52-09NA29552.

  12. Water resources

    International Nuclear Information System (INIS)

    2002-01-01

    The report entitled Climate Change Impacts and Adaptation : A Canadian Perspective, presents a summary of research regarding the impacts of climate change on key sectors over the past five years as it relates to Canada. This chapter on water resources describes how climate change will affect the supply of water in Canada. Water is one of Canada's greatest resources, which contributes about $7.5 to 23 billion per year to the Canadian economy. The decisions taken to adapt to climate change within the water resources sector will have profound implications in many other areas such as agriculture, human health, transportation and industry. The water related problems include water quality issues that relate to water shortages from droughts, or excesses from floods. The Intergovernmental Panel on Climate Change forecasts an increase in global average surface air temperatures of 1.4 to 5.8 degrees C by 2100. Such a change would impact the hydrological cycle, affecting runoff, evaporation patterns, and the amount of water stored in glaciers, lakes, wetlands and groundwater. The uncertainty as to the magnitude of these changes is due to the difficulty that climate models have in projecting future changes in regional precipitation patterns and extreme events. This chapter presents potential impacts of climate change on water resources in the Yukon, British Columbia, the Prairies, the Great Lakes basin, the Atlantic provinces, and the Arctic and Subarctic. The associated concerns for each region were highlighted. Adaptation research has focused on the impacts of supply and demand, and on options to adapt to these impacts. 60 refs., 2 tabs., 1 fig

  13. Resource Abundance and Resource Dependence in China

    NARCIS (Netherlands)

    Ji, K.; Magnus, J.R.; Wang, W.

    2010-01-01

    This paper reconsiders the ‘curse of resources’ hypothesis for the case of China, and distinguishes between resource abundance, resource rents, and resource dependence. Resource abundance and resource rents are shown to be approximately equivalent, and their association with resource dependence

  14. Internet and Electronic Information Management

    Science.gov (United States)

    2004-12-01

    centers to form consortia and share electronic information sources. Although traditional resource sharing arrangements encouraged competition rather...outside world, through public relations and through marketing information products or services, to its own competitive advantage (Davenport 1997: 193-217... electronic information sources are a challenge for electronic information managers. Libraries and information centers are no longer “the only game in town

  15. Automotive electronics design fundamentals

    CERN Document Server

    Zaman, Najamuz

    2015-01-01

    This book explains the topology behind automotive electronics architectures and examines how they can be profoundly augmented with embedded controllers. These controllers serve as the core building blocks of today’s vehicle electronics. Rather than simply teaching electrical basics, this unique resource focuses on the fundamental concepts of vehicle electronics architecture, and details the wide variety of Electronic Control Modules (ECMs) that enable the increasingly sophisticated "bells & whistles" of modern designs.  A must-have for automotive design engineers, technicians working in automotive electronics repair centers and students taking automotive electronics courses, this guide bridges the gap between academic instruction and industry practice with clear, concise advice on how to design and optimize automotive electronics with embedded controllers.

  16. Floristic composition of the cerrado in the Pé-de-Gigante Reserve (Santa Rita do Passa Quatro, southeastern Brazil Composição florística do cerrado na Reserva Pé-de-Gigante (Santa Rita do Passa Quatro, SP

    Directory of Open Access Journals (Sweden)

    Marco Antônio Batalha

    2001-12-01

    Full Text Available We studied a 1225 ha area, composed mainly of cerrado, in Santa Rita do Passa Quatro, São Paulo State, southeastern Brazil (21°36-38'S, 47°36-39'W. In three cerrado physiognomies (campo cerrado -- a wooded savanna, cerrado sensu stricto -- a woodland, and cerradão -- a tall woodland, we collected all vascular plants in reproductive stage, and identified them to species level. We found 360 species, representing 236 genera and 69 families. The richest families were: Asteraceae, Fabaceae, Poaceae, and Rubiaceae. The savanna physiognomies were richer than the forest one. The ratio between herbaceous and woody species was approximately 2:1. We analysed the whole flora and its two components separately, woody and herbaceous, comparing them with other disjunct cerrado areas. We obtained similarity values (Sørensen index from 0.47 to 0.81, which showed that the 3 diversity of the cerrado was higher in the herbaceous component than in the woody one.Estudamos uma área de 1225 ha, composta principalmente por cerrado, situada em Santa Rita do Passa Quatro, estado de São Paulo (21°36-38'S, 47°36-39'W. Em três fisionomias de cerrado (campo cerrado, cerrado sensu stricto e cerradão, coletamos, durante 18 meses, em excursões mensais, espécimes em fase fértil e os identificamos em nível específico. Encontramos 360 espécies, pertencentes a 236 gêneros e 69 famílias. As fam��lias mais ricas foram: Fabaceae, Asteraceae, Poaceae e Rubiaceae. As fisionomias savânicas foram mais ricas do que a florestal. A razão entre espécies arbustivo-arbóreas e herbáceo-subarbustivas foi de aproximadamente 2:1. Analisamos a flora como um todo e seus componentes herbáceo-subarbustivo e arbustivo-arbóreo separadamente, comparando-os com outras áreas disjuntas de cerrado. Dessa comparação, obtivemos valores de similaridade (índice de Sørensen de 0,47 a 0,81, que mostraram que a diversidade 3 foi maior no componente herbáceo-subarbustivo do que no

  17. Florística de lianas em um fragmento de floresta estacional semidecidual, Parque Estadual de Vassununga, Santa Rita do Passa Quatro, SP, Brasil Floristic of lianas in a fragment of seasonal semidecidual forest State Park of Vassununga, Santa Rita do Passa Quatro, São Paulo State, Brazil

    Directory of Open Access Journals (Sweden)

    Yara Junqueira de Azevedo Tibiriçá

    2006-06-01

    Full Text Available Embora o conhecimento sobre a florística dos fragmentos de florestas estacionais semideciduais tenha crescido nos últimos anos, ainda sabe-se pouco sobre a comunidade de lianas (lenhosas ou herbáceas nesses fragmentos. Assim, foi realizado o levantamento florístico de lianas na gleba Maravilha, pertencente ao Parque Estadual de Vassununga (Santa Rita do Passa Quatro, SP, a fim de colaborar com o conhecimento dessa comunidade e subsidiar futuros trabalhos que envolvam essa forma de vida. A área de estudo compreende 127,08 ha, com inverno seco e temperatura média anual de 22 ºC. Para a coleta do material, percorreu-se mensalmente toda a borda do fragmento e três trilhas no interior da mata, de agosto/2002 a setembro/2003. Foram identificadas 120 espécies de lianas, pertencentes a 30 famílias e 71 gêneros, das quais 51% das espécies são volúveis, 42% apresentam gavinhas e apenas 7% são escandentes. As famílias mais representativas em número de espécies foram: Bignoniaceae (26, Malpighiaceae (14, Sapindaceae (12 e Asteraceae (9. Houve baixa similaridade florística entre as espécies de lianas presentes na gleba Maravilha em relação a outras áreas de florestas estacionais semideciduais do interior paulista.Although the knowledge about the floristic composition of the fragments of seasonal semidecidual forest had grown in the last few years, little is known about the liana communities (woody vines and herbaceous vines in those fragments. To collaborate with the knowledgement of the lianas and subsidize future works involving this life form, a floristic survey of the liana species occurring at the fragment Maravilha of the State Park of Vassununga (Santa Rita do Passa Quatro - SP was carried out. The study area comprised 127.08ha, with average temperature of 22 ºC. The whole border of the forest fragment and three tracks inside the forest were surveyed monthly between August 2002 and September 2003. One hundred and twenty species

  18. Uranium resource processing. Secondary resources

    International Nuclear Information System (INIS)

    Gupta, C.K.; Singh, H.

    2003-01-01

    This book concentrates on the processing of secondary sources for recovering uranium, a field which has gained in importance in recent years as it is environmental-friendly and economically in tune with the philosophy of sustainable development. Special mention is made of rock phosphate, copper and gold tailings, uranium scrap materials (both natural and enriched) and sea water. This volume includes related area of ore mineralogy, resource classification, processing principles involved in solubilization followed by separation and safety aspects

  19. Energy resources

    CERN Document Server

    Simon, Andrew L

    1975-01-01

    Energy Resources mainly focuses on energy, including its definition, historical perspective, sources, utilization, and conservation. This text first explains what energy is and what its uses are. This book then explains coal, oil, and natural gas, which are some of the common energy sources used by various industries. Other energy sources such as wind, solar, geothermal, water, and nuclear energy sources are also tackled. This text also looks into fusion energy and techniques of energy conversion. This book concludes by explaining the energy allocation and utilization crisis. This publ

  20. Effects of age on long-term outcomes after a routine invasive or selective invasive strategy in patients presenting with non-ST segment elevation acute coronary syndromes: a collaborative analysis of individual data from the FRISC II - ICTUS - RITA-3 (FIR) trials

    NARCIS (Netherlands)

    Damman, Peter; Clayton, Tim; Wallentin, Lars; Lagerqvist, Bo; Fox, Keith A. A.; Hirsch, Alexander; Windhausen, Fons; Swahn, Eva; Pocock, Stuart J.; Tijssen, Jan G. P.; de Winter, Robbert J.

    2012-01-01

    Objective To perform a patient-pooled analysis of a routine invasive versus a selective invasive strategy in elderly patients with non-ST segment elevation acute coronary syndrome. Methods A meta-analysis was performed of patient-pooled data from the FRISC IIeICTUSeRITA-3 (FIR) studies. (Un)adjusted

  1. Annabela Rita, Fernando Cristóvão (e ds., Daniela Marcheschi (Prefácio. Fabricar a Inovação – O Processo Criativo em Questão nas Ciências, nas Letras e nas Artes

    Directory of Open Access Journals (Sweden)

    Luísa Marinho Antunes

    2017-06-01

    Full Text Available Recensione del volume Annabela Rita e Fernando Cristóvão (eds. Fabricar a Inovação – O Processo Criativo em Questão nas Ciências, nas Letras e nas Artes, coord. Prefácio Daniela Marcheschi. Lisboa: Gradiva, 2016. Stampa (pp.396 seguita dalla versione italiana della Prefazione.

  2. Electronic technology

    International Nuclear Information System (INIS)

    Kim, Jin Su

    2010-07-01

    This book is composed of five chapters, which introduces electronic technology about understanding of electronic, electronic component, radio, electronic application, communication technology, semiconductor on its basic, free electron and hole, intrinsic semiconductor and semiconductor element, Diode such as PN junction diode, characteristic of junction diode, rectifier circuit and smoothing circuit, transistor on structure of transistor, characteristic of transistor and common emitter circuit, electronic application about electronic equipment, communication technology and education, robot technology and high electronic technology.

  3. Mineral resources

    International Nuclear Information System (INIS)

    1991-09-01

    This paper reports that to prevent the concentration of control over federal oil and gas resources in a few companies or individuals, Congress has limited the number of acres of oil and gas leases that one party may control in a single state. An exception to this limitation involves lease acreage within the boundaries of development contracts. These contracts permit oil and gas lease operators and pipeline companies to contract with enough lessees to economically justify large-scale drilling operations for the production and transportation of oil and gas, subject to approval by the Secretary of the Interior, who must find that such contracts are in the public interest. Since 1986 Interior has entered into or approved 10 contracts with 12 lease operators for exploration of largely unleased federal lands-ranging from about 180,000 to 3.5 million acres in four western states-and has designated them as developmental contracts. GAO believes that the 10 contracts do not satisfy the legal requirements for development contracts because they are for oil and gas exploration on largely unleased federal lands, rather than for developing existing leases. By designating the 10 contracts as development contracts, Interior has enabled nine of the 12 contract parties to accumulate lease acreage that vastly exceeds the statutory acreage limitation. All nine of the contract parties were major or large independent oil companies. As a result, other parties who wish to participate in developing federal oil and gas resources within the four states may be adversely affected because the parties to Interior's contracts have been able to compete for and obtain lease acreage beyond the statutory acreage limitation. Although Interior believes that the Secretary has the discretion under law to use development contracts in the current manner, in April 1989 it ceased issuing these contracts pending completion of GAO's review

  4. The Electron

    Energy Technology Data Exchange (ETDEWEB)

    Thomson, George

    1972-01-01

    Electrons are elementary particles of atoms that revolve around and outside the nucleus and have a negative charge. This booklet discusses how electrons relate to electricity, some applications of electrons, electrons as waves, electrons in atoms and solids, the electron microscope, among other things.

  5. Hard electronics; Hard electronics

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    Hard material technologies were surveyed to establish the hard electronic technology which offers superior characteristics under hard operational or environmental conditions as compared with conventional Si devices. The following technologies were separately surveyed: (1) The device and integration technologies of wide gap hard semiconductors such as SiC, diamond and nitride, (2) The technology of hard semiconductor devices for vacuum micro- electronics technology, and (3) The technology of hard new material devices for oxides. The formation technology of oxide thin films made remarkable progress after discovery of oxide superconductor materials, resulting in development of an atomic layer growth method and mist deposition method. This leading research is expected to solve such issues difficult to be easily realized by current Si technology as high-power, high-frequency and low-loss devices in power electronics, high temperature-proof and radiation-proof devices in ultimate electronics, and high-speed and dense- integrated devices in information electronics. 432 refs., 136 figs., 15 tabs.

  6. Pb and Sr isotopic systematics of some basalts and sulfides from the East Pacific Rise at 21/sup 0/N (project RITA)

    Energy Technology Data Exchange (ETDEWEB)

    Vidal, P. (Centre National de la Recherche Scientifique, 35 - Rennes (France). Centre Armoricain d' Etude Structurale des Socles); Clauer, N. (Centre National de la Recherche Scientifique, 67 - Strasbourg (France). Centre de Sedimentologie et Geochimie de la Surface)

    1981-10-01

    Tholeiitic basalts and sulfide deposits from the 'Cyana' and 'Alvin' diving programs (RITA project) on the East Pacific Rise were analyzed for Pb and Sr isotopes. The basalt data plot within the field defined previously by other East Pacific Rise basalts (/sup 206/Pb//sup 204/Pb: 18.35-18.58; /sup 207/Pb//sup 204/Pb: 15.48-15.53; /sup 208/Pb//sup 204/Pb: 37.8-38.1; /sup 87/Sr//sup 86/Sr: 0.7022-0.7025). Pb, U and Sr contents (approx. equal to 0.5, approx. equal to 0.05 and approx. equal to 110 ppm, respectively) and ..mu.. values (approx. equal to 6) are typical of MORB, whereas Th/U ratios (approx. equal to 3.5) are significantly higher. The Pb isotopic ratios of the sulfide samples are very homogeneous (/sup 206/Pb//sup 204/Pb approx. equal to 18.47, /sup 207/Pb//sup 204/Pb approx. equal to 15.49, /sup 208/Pb//sup 204/Pb approx. equal to 37.90), and plot in the middle of the basalt field. This indicates that the sulfide Pb was derived from the basaltic crust without any significant contribution from either seawater or hemipelagic sediments, and the solutions from which the sulfiedes were deposited had uniform Pb isotopic composition. The Pb contents of three sulfide samples is relatively high (170-1310 ppm). The Sr contents of five sulfide samples are widely scattered from 12 to 210 ppm, with /sup 87/Sr//sup 86/Sr ratios intermediate between basaltic and seawater values (0.70554 +- 0.00005 to 0.70795 +- 0.00011). Leaching experiments show that both basalt-derived Sr and seawater Sr were present in the solutions which deposited the sulfides. In some cases, Sr was also adsorbed from seawater onto the sulfides following their deposition. Basalt-derived Sr and seawater Sr are also present in associated non-sulfide phases.

  7. Social Studies Online Resources. Media Corner.

    Science.gov (United States)

    Wilson, Jeri, Ed.

    1995-01-01

    Maintains that three types of social studies activities are found on the information highway: (1) electronic mail; (2) information; and (3) conferencing. Describes examples of each. Discusses commercial services and resource materials and provides references to online services. (CFR)

  8. The Biomedical Resource Ontology (BRO) to enable resource discovery in clinical and translational research.

    Science.gov (United States)

    Tenenbaum, Jessica D; Whetzel, Patricia L; Anderson, Kent; Borromeo, Charles D; Dinov, Ivo D; Gabriel, Davera; Kirschner, Beth; Mirel, Barbara; Morris, Tim; Noy, Natasha; Nyulas, Csongor; Rubenson, David; Saxman, Paul R; Singh, Harpreet; Whelan, Nancy; Wright, Zach; Athey, Brian D; Becich, Michael J; Ginsburg, Geoffrey S; Musen, Mark A; Smith, Kevin A; Tarantal, Alice F; Rubin, Daniel L; Lyster, Peter

    2011-02-01

    The biomedical research community relies on a diverse set of resources, both within their own institutions and at other research centers. In addition, an increasing number of shared electronic resources have been developed. Without effective means to locate and query these resources, it is challenging, if not impossible, for investigators to be aware of the myriad resources available, or to effectively perform resource discovery when the need arises. In this paper, we describe the development and use of the Biomedical Resource Ontology (BRO) to enable semantic annotation and discovery of biomedical resources. We also describe the Resource Discovery System (RDS) which is a federated, inter-institutional pilot project that uses the BRO to facilitate resource discovery on the Internet. Through the RDS framework and its associated Biositemaps infrastructure, the BRO facilitates semantic search and discovery of biomedical resources, breaking down barriers and streamlining scientific research that will improve human health. Copyright © 2010 Elsevier Inc. All rights reserved.

  9. Electron radiography

    Science.gov (United States)

    Merrill, Frank E.; Morris, Christopher

    2005-05-17

    A system capable of performing radiography using a beam of electrons. Diffuser means receive a beam of electrons and diffuse the electrons before they enter first matching quadrupoles where the diffused electrons are focused prior to the diffused electrons entering an object. First imaging quadrupoles receive the focused diffused electrons after the focused diffused electrons have been scattered by the object for focusing the scattered electrons. Collimator means receive the scattered electrons and remove scattered electrons that have scattered to large angles. Second imaging quadrupoles receive the collimated scattered electrons and refocus the collimated scattered electrons and map the focused collimated scattered electrons to transverse locations on an image plane representative of the electrons' positions in the object.

  10. Information resources

    Science.gov (United States)

    Friend, Milton; Franson, J. Christian; Friend, Milton; Gibbs, Samantha E.J.; Wild, Margaret A.

    2015-10-19

    During recent decades, natural resources agency personnel and others involved with the management and stewardship of wildlife have experienced an increasing need to access information and obtain technical assistance for addressing a diverse array of wildlife disease issues. This Chapter provides a broad overview of selected sources for obtaining supplemental information and technical assistance for addressing wildlife disease issues in North America. Specifically, examples of existing major wildlife disease programs focusing on free-ranging wildlife populations are highlighted; training opportunities for enhancing within-agency wildlife disease response are identified; a selected reading list of wildlife disease references is provided; and selected Web sites providing timely information on wildlife disease are highlighted. No attempt is made to detail all the North American programs and capabilities that address disease in free-ranging wildlife populations. Instead, this Chapter is focused on enhancing awareness of the types of capabilities that exist as potential sources for assistance and collaboration between wildlife conservation agency personnel and others in addressing wildlife disease issues.

  11. GENDER ANALYSIS OF ELECTRONIC INFORMATION

    African Journals Online (AJOL)

    use of internet Search engines such as google, yahoo and other free internet resources was found ... empirical studies are undertaken to examine the influence of gender ... H3: Perceived ease of use is positively related to the use of electronic.

  12. Oscillator clustering in a resource distribution chain

    DEFF Research Database (Denmark)

    Postnov, D.; Sosnovtseva, Olga; Mosekilde, Erik

    2005-01-01

    separate the inherent dynamics of the individual oscillator from the properties of the coupling network. Illustrated by examples from microbiological population dynamics, renal physiology, and electronic oscillator theory, we show how competition for primary resources in a resource distribution chain leads...

  13. Shaping the Electronic Library--The UW-Madison Approach.

    Science.gov (United States)

    Dean, Charles W., Ed.; Frazier, Ken; Pope, Nolan F.; Gorman, Peter C.; Dentinger, Sue; Boston, Jeanne; Phillips, Hugh; Daggett, Steven C.; Lundquist, Mitch; McClung, Mark; Riley, Curran; Allan, Craig; Waugh, David

    1998-01-01

    This special theme section describes the University of Wisconsin-Madison's experience building its Electronic Library. Highlights include integrating resources and services; the administrative framework; the public electronic library, including electronic publishing capability and access to World Wide Web-based and other electronic resources;…

  14. Felismina e Libertina vão à escola: notas sobre a escolarização nas freguesias de Santa Rita e Santana (Rio de Janeiro, 1888-1906 - Felismina and Libertina go to school: notes on schooling in the parishes of Santa Rita and Santana (RJ, 1888-1906

    Directory of Open Access Journals (Sweden)

    Alessandra Frota Martinez Schueler

    2015-05-01

    Full Text Available Neste artigo se analisa as possibilidades, tensões e limites da escolarização na cidade do Rio de Janeiro, no período da abolição e no pós-abolição (1888-1906. A pesquisa incide sobre regiões de alta densidade demográfica, com índices crescentes de matrículas nas escolas públicas. Pensar o contexto do pós-abolição no âmbito da história da educação visa a compreender como os projetos nacionais e locais direcionados à instrução popular interagiam com expectativas e ações de libertos e livres, em diálogo com os estudos historiográficos concernentes às lutas dessa população pelo acesso à educação.  Palavras-chave: escolarização, pós-abolição, Rio de Janeiro.FELISMINA AND LIBERTINA GO TO SCHOOL: NOTES ON SCHOOLING IN THE PARISHES OF SANTA RITA AND SANTANA (RIO DE JANEIRO, 1888-1906 AbstractThe article analyzes the possibilities, tensions and limits of schooling in the city of Rio de Janeiro, in the period during the slavery abolition and post-abolition (1888-1906. The research focuses on regions of high population density, with increasing enrollment rates in public schools. Thinking the context of post-abolition within the history of education aims to understand how national and local projects targeted at popular instruction interacted with expectations and actions of freedmen and free people in a dialogue with historiographical studies concerning the struggles of this population for educational access.Key-words: schooling, post-abolition, Rio de Janeiro.FELISMINAY LIBERTINA VAN A LA ESCUELA: NOTAS SOBRE LA ESCOLARIZACIÓN EN LAS FELIGRESÍAS DE SANTA RITA Y SANTANA ResumenEl artículo analiza las posibilidades, las tensiones y los límites de la escolarización en la ciudad de Río de Janeiro, en el período de la abolición y post-abolición (1888-1906. Esta investigación está centrada en las regiones con alta densidad de población, con índices crecientes de matrículas en las escuelas públicas. Se

  15. DEFINICIÓN DE UN MODELO DE SEGURIDAD PARA LA RED DE INVESTIGACIÓN DE TECNOLOGÍA AVANZADA DE LA UNIVERSIDAD DISTRITAL “FRANCISCO JOSÉ DE CALDAS” RITA-UD

    Directory of Open Access Journals (Sweden)

    Diego Rocha

    2011-11-01

    Full Text Available Uno de los aspectos más importantes dentro de las networking se relaciona con la protección de la información. Este trabajo permite identificar los aspectos más importantes a considerar en la definición de un modelo de seguridad para la red de investigación de tecnología avanzada de la Universidad Distrital Francisco José de Caldas RITA-UD basado en la aplicación de las normas ISO27001 y NTC-ISO/IEC17799.El diseño final obtenido es una propuesta para la implementación de un Firewall Cisco ASA5520.

  16. Electrons, Electronic Publishing, and Electronic Display.

    Science.gov (United States)

    Brownrigg, Edwin B.; Lynch, Clifford A.

    1985-01-01

    Provides a perspective on electronic publishing by distinguishing between "Newtonian" publishing and "quantum-mechanical" publishing. Highlights include media and publishing, works delivered through electronic media, electronic publishing and the printed word, management of intellectual property, and recent copyright-law issues…

  17. 研究/電子資源使用統計標準與規範之探討/陳雪華;許嘉珍;朱雅琦 | Study of the Electronic Resources Usage Statistics Standards and Guidelines/ Hsueh-Hua Chen;Chia-Chen Hsu;Ya-Chi Chu

    Directory of Open Access Journals (Sweden)

    陳雪華、許嘉珍、朱雅琦

    2007-04-01

    Full Text Available

    近年來,由於資訊科技的進步,圖書館中的電子資源數量快速增加,所佔預算金額比例也大幅增長。圖書館希望能夠透過評鑑電子資源的使用,以便能夠在電 子資源館藏發展等方面做出正確的決策。由於體認到電子資源使用統計之重要性,圖書館界與相關組織紛紛發展或修訂圖書館統計標準,增列電子資源使用統計的項 目以充分反映圖書館電子資源使用之狀況。本文主要採用文獻分析法以及內容分析法,收集探討並比較近軍來國內外電子資源使用統計之相關規範及標準,包含 ISO 2789、 ICOLC Guidelines、州ANSI/NISO Z39.7、CNS13151、ARL E-Metrlcs、E-Measures Project、以及Project COUNTER等。

    Recently, due to the advances of information technology, electronic resources are gradually replacing print resources as the largest consumer of library acquisition budgets. Logically, libraries want to evaluate the usage of electronic resources and incorporate the results into their decision making regarding electronic resource acquisition. Over these years, there is a general awareness among libraries to develop statistics standards and guidelines for library electronic resources usage. In this paper, literature review and content analysis methods are used to compare several library statistics standards, including: ISO 2789 、ICOLC Guidelines、ANSI/NISO Z39.7、CNS13151、ARL E-Metrics、E-Measures Project、and Project COUNTER etc.

    頁次:89-102

  18. Environmental chemical data for perishable sediments and soils collected in New Orleans, Louisiana, and along the Louisiana Delta following Hurricanes Katrina and Rita, 2005

    Science.gov (United States)

    Witt, Emitt C.; Shi, Honglan; Karstensen, Krista A.; Wang, Jianmin; Adams, Craig D.

    2008-01-01

    In October 2005, nearly one month after Hurricanes Katrina and Rita, a team of scientists from the U.S. Geological Survey and the Missouri University of Science and Technology deployed to southern Louisiana to collect perishable environmental data resulting from the impacts of these storms. Perishable samples collected for this investigation are subject to destruction or ruin by removal, mixing, or natural decay; therefore, collection is time-critical following the depositional event. A total of 238 samples of sediment, soil, and vegetation were collected to characterize chemical quality. For this analysis, 157 of the 238 samples were used to characterize trace element, iron, total organic carbon, pesticide, and polychlorinated biphenyl concentrations of deposited sediment and associated shallow soils. In decreasing order, the largest variability in trace element concentration was detected for lead, vanadium, chromium, copper, arsenic, cadmium, and mercury. Lead was determined to be the trace element of most concern because of the large concentrations present in the samples ranging from 4.50 to 551 milligrams per kilogram (mg/kg). Sequential extraction analysis of lead indicate that 39.1 percent of the total lead concentration in post-hurricane sediment is associated with the iron-manganese oxide fraction. This fraction is considered extremely mobile under reducing environmental conditions, thereby making lead a potential health hazard. The presence of lead in post-hurricane sediments likely is from redistribution of pre-hurricane contaminated soils and sediments from Lake Pontchartrain and the flood control canals of New Orleans. Arsenic concentrations ranged from 0.84 to 49.1 mg/kg. Although Arsenic concentrations generally were small and consistent with other research results, all samples exceeded the U.S. Environmental Protection Agency’s Human Health Medium-Specific Screening Level of 0.39 mg/kg. Mercury concentrations ranged from 0.02 to 1.30 mg

  19. Avaliação sorológica para detecção de anticorpos anti-Leishmania em cães e gatos no bairro de Santa Rita de Cássia, Município de Barra Mansa, Estado do Rio de Janeiro Serological evaluation for detection of anti-Leishmania antibodies in dogs and cats in the district of Santa Rita de Cássia, municipality of Barra Mansa, State of Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    Fabiano Borges Figueiredo

    2009-04-01

    Full Text Available A partir de um caso canino de leishmaniose tegumentar americana na localidade de Santa Rita de Cássia, município de Barra Mansa, Rio de Janeiro, foi realizado um inquérito sorológico em 177 cães e 43 gatos. Na avaliação das amostras de soros caninos, 10% foram positivos na reação de imunofluorescência indireta e 10,7% no ensaio imunoenzimático. Entre as amostras de soros felinos testados, nenhum animal foi positivo na reação de imunofluorescência indireta e apenas um (2,4% felino apresentou reação positiva ao ensaio imunoenzimático. A detecção de Leishmania braziliensis, autóctone em Barra Mansa, faz um alerta para a instalação de um possível foco de leishmaniose tegumentar americana nessa região.From a canine case of american cutaneous leishmaniasis in the locality of Santa Rita de Cássia, municipality of Barra Mansa, Rio de Janeiro, a serological survey was performed on 177 dogs and 43 cats. Evaluation of the canine serum samples showed that 10% had a positive reaction in the indirect immunofluorescence test and 10.7% in the enzyme-linked immunosorbent assay. Among the feline serum samples tested, none of the animals had a positive reaction in the indirect immunofluorescence test and only one (2.4% showed a positive reaction in the enzyme-linked immunosorbent assay. The detection of an autochthonous case of Leishmania braziliensis in Barra Mansa gives warning that a focus of american cutaneous leishmaniasis is possibly becoming established in this region.

  20. Electron detector

    International Nuclear Information System (INIS)

    Hashimoto, H.; Mogami, A.

    1975-01-01

    A device for measuring electron densities at a given energy level in an electron beam or the like having strong background noise, for example, in the detection of Auger electric energy spectrums is described. An electron analyzer passes electrons at the given energy level and at the same time electrons of at least one adjacent energy level. Detecting means associated therewith produce signals indicative of the densities of the electrons at each energy level and combine these signals to produce a signal indicative of the density of the electrons of the given energy level absent background noise

  1. World resources: engineering solutions

    Energy Technology Data Exchange (ETDEWEB)

    1976-01-01

    The proceedings include 10 papers that contribute to population environment; fossil fuel resources and energy conservation; nuclear and solar power; production of ores and manufacture and use of metallic resources; resources of manufactured and natural nonmetallic materials; water as a reusable resource; and timber as a replaceable resource.

  2. Effects of age on long-term outcomes after a routine invasive or selective invasive strategy in patients presenting with non-ST segment elevation acute coronary syndromes: a collaborative analysis of individual data from the FRISC II - ICTUS - RITA-3 (FIR) trials.

    Science.gov (United States)

    Damman, Peter; Clayton, Tim; Wallentin, Lars; Lagerqvist, Bo; Fox, Keith A A; Hirsch, Alexander; Windhausen, Fons; Swahn, Eva; Pocock, Stuart J; Tijssen, Jan G P; de Winter, Robbert J

    2012-02-01

    To perform a patient-pooled analysis of a routine invasive versus a selective invasive strategy in elderly patients with non-ST segment elevation acute coronary syndrome. A meta-analysis was performed of patient-pooled data from the FRISC II-ICTUS-RITA-3 (FIR) studies. (Un)adjusted HRs were calculated by Cox regression, with adjustments for variables associated with age and outcomes. The main outcome was 5-year cardiovascular death or myocardial infarction (MI) following routine invasive versus selective invasive management. Regarding the 5-year composite of cardiovascular death or MI, the routine invasive strategy was associated with a lower hazard in patients aged 65-74 years (HR 0.72, 95% CI 0.58 to 0.90) and those aged ≥75 years (HR 0.71, 95% CI 0.55 to 0.91), but not in those aged RITA-3).

  3. Electron/electron acoustic instability

    International Nuclear Information System (INIS)

    Gary, S.P.

    1987-01-01

    The electron acoustic wave becomes a normal mode of an unmagnetized collisionless plasma in the presence of two electron components with similar densities, but strongly disparate temperatures. The characteristic frequency of this mode is the plasma frequency of the cooler electron component. If these two electron components have a relative drift speed several times the thermal speed of the cooler component, the electron/electron acoustic instability may arise. This paper describes the parametric dependences of the threshold drift speed and maximum growth rate of this instability, and compares these with the same properties of the electron/ion acoustic instability. Under the condition of zero current, the electron/ion acoustic instability typically has the lower threshold drift speed, so that observation of the electron/electron acoustic instability is a strong indication of the presence of an electrical current in the plasma

  4. Innovations in electronic services

    Directory of Open Access Journals (Sweden)

    Dagmara Wach

    2011-12-01

    Full Text Available Summarry Existence in electronic business has become increasingly difficult. High competition and considerable financial resources needed to enter electronic market are the problems of most micro and small sized enterprises, starting or developing their business. Nevertheless, there is a market niche for them, which can ensure success and grant partial financing of the business. This niche are small web projects, providing the customer with personalized service, hitting his tastes and meeting immediate needs. A projects that large websites are unable to perform. Financial sourcing of those projects comes from EU subsidies, in the framework of the Działanie 8.1. PO IG, 2007-2013.

  5. Electronic emission and electron guns

    International Nuclear Information System (INIS)

    Roy, Amitava

    2010-01-01

    This paper reviews the process of electron emission from metal surface. Although electrons move freely in conductors like metals, they normally do not leave the metal without some manipulation. In fact, heating and bombardment are the two primary ways in which electrons are emitted through the use of a heating element behind the cathode (termed thermionic emission) or as a result of bombardment with a beam of electrons, ions, or metastable atoms (termed secondary emission). Another important emission mechanism called Explosive Electron Emission (EEE) is also often used in various High Voltage Pulse Power Systems to generate very high current (few hundreds of kA) pulsed electron beams. The electron gun is the device in that it shoots off a continuous (or pulsed) stream of electrons. A brief idea about the evolution of the electron gun components and their basis of functioning are also discussed. (author)

  6. Sticker electronics

    KAUST Repository

    Hussain, Muhammad Mustafa; Torres Sevilla, Galo Andres; Diaz Cordero, Marlon Steven

    2017-01-01

    Electronic stickers may be manufactured on flexible substrates (110, 120, 130) as layers and packaged together. The package may then have an adhesive applied to one side to provide capability for sticking the electronic devices to surfaces

  7. ELECTRONIC SIGNATURES

    African Journals Online (AJOL)

    10332324

    "[to] promote the understanding and, acceptance of and growth in the number of electronic transactions .... Chapter III of the ECT Act is based on the UNCITRAL Model Law on Electronic. Commerce ... Communications Technology Law 146. 22.

  8. Electronic components

    CERN Document Server

    Colwell, Morris A

    1976-01-01

    Electronic Components provides a basic grounding in the practical aspects of using and selecting electronics components. The book describes the basic requirements needed to start practical work on electronic equipment, resistors and potentiometers, capacitance, and inductors and transformers. The text discusses semiconductor devices such as diodes, thyristors and triacs, transistors and heat sinks, logic and linear integrated circuits (I.C.s) and electromechanical devices. Common abbreviations applied to components are provided. Constructors and electronics engineers will find the book useful

  9. Understand electronics

    CERN Document Server

    Bishop, Owen

    2013-01-01

    Understand Electronics provides a readable introduction to the exciting world of electronics for the student or enthusiast with little previous knowledge. The subject is treated with the minimum of mathematics and the book is extensively illustrated.This is an essential guide for the newcomer to electronics, and replaces the author's best-selling Beginner's Guide to Electronics.The step-by-step approach makes this book ideal for introductory courses such as the Intermediate GNVQ.

  10. Electronic Commerce

    OpenAIRE

    Slavko Đerić

    2016-01-01

    Electronic commerce can be defined in different ways. Any definition helps to understand and explain that concept as better as possible.. Electronic commerce is a set of procedures and technologies that automate the tasks of financial transactions using electronic means. Also, according to some authors, electronic commerce is defined as a new concept, which is being developed and which includes process of buying and selling or exchanging products, services or information via computer networks...

  11. Electronic Publishing.

    Science.gov (United States)

    Lancaster, F. W.

    1989-01-01

    Describes various stages involved in the applications of electronic media to the publishing industry. Highlights include computer typesetting, or photocomposition; machine-readable databases; the distribution of publications in electronic form; computer conferencing and electronic mail; collaborative authorship; hypertext; hypermedia publications;…

  12. Building the electronic industry's roadmaps

    Science.gov (United States)

    Boulton, William R.

    1995-02-01

    JTEC panelists found a strong consistency among the electronics firms they visited: all the firms had clear visions or roadmaps for their research and development activities and had committed resources to ensure that they achieve targeted results. The overarching vision driving Japan's electronics industry is that of achieving market success through developing appealing, high-quality, low-cost consumer goods - ahead of the competition. Specifics of the vision include improving performance, quality, and portability of consumer electronics products. Such visions help Japanese companies define in detail the roadmaps they will follow to develop new and improved electronic packaging technologies.

  13. Electronic Recruitment at CERN

    CERN Multimedia

    2004-01-01

    The Human Resources Department switches to electronic recruitment. From now on whenever you are involved in a recruitment action you will receive an e-mail giving you access to a Web folder. Inside you will find a shortlist of applications drawn up by the Human Resources Department. This will allow you to consult the folder, at the same time as everyone else involved in the recruitment process, for the vacancy you are interested in. This new electronic recruitment system, known as e-RT, will be introduced in a presentation given at 10 a.m. on 11 February in the Main Auditorium. Implemented by AIS (Administrative Information Services) and the Human Resources Department, e-RT will cover vacancies open in all of CERN's recruitment programmes. The electronic application system was initially made available to technical students in July 2003. By December it was extended to summer students, fellows, associates and Local Staff. Geraldine Ballet from the Recruitment Service prefers e-RT to mountains of paper! The Hu...

  14. Sticker electronics

    KAUST Repository

    Hussain, Muhammad Mustafa

    2017-09-08

    Electronic stickers may be manufactured on flexible substrates (110, 120, 130) as layers and packaged together. The package may then have an adhesive applied to one side to provide capability for sticking the electronic devices to surfaces. The stickers can be wrappable, placed on surfaces, glued on walls or mirrors or wood or stone, and have electronics (112, 122, 132) which may or may not be ultrathin. Packaging for the electronic sticker can use polymer on cellulose manufacturing and/or three dimensional (3-D) printing. The electronic stickers may provide lighting capability, sensing capability, and/or recharging capabilities.

  15. Basic electronics

    CERN Document Server

    Holbrook, Harold D

    1971-01-01

    Basic Electronics is an elementary text designed for basic instruction in electricity and electronics. It gives emphasis on electronic emission and the vacuum tube and shows transistor circuits in parallel with electron tube circuits. This book also demonstrates how the transistor merely replaces the tube, with proper change of circuit constants as required. Many problems are presented at the end of each chapter. This book is comprised of 17 chapters and opens with an overview of electron theory, followed by a discussion on resistance, inductance, and capacitance, along with their effects on t

  16. Network resource management

    NARCIS (Netherlands)

    2009-01-01

    The invention provides real time dynamic resource management to improve end-to-end QoS by mobile devices regularly updating a resource availability server (RAS) with resource update information. Examples of resource update information are device battery status, available memory, session bandwidth,

  17. The Global Resource Nexus

    NARCIS (Netherlands)

    Ridder, M. de; Duijne, F. van; Jong, S. de; Jones, J.; Luit, E. van; Bekkers, F.F.; Auping, W.

    2014-01-01

    Supply and demand of resources are connected in a complex way. This interconnectivity has been framed as the global resource nexus and can conceivebly include all types of resources. This study focus on the nexus of five essential natural resources: land, food, energy, water and minerals. Together

  18. Knowledge and Natural Resources

    DEFF Research Database (Denmark)

    Bertelsen, Rasmus Gjedssø; Justinussen, Jens Christian Svabo

    2016-01-01

    Arctic economies are generally natural resource based economies, whether they are indigenous economies largely dependent on living on the land or industrialized economies depending on marine resources, mineral resources or fossil or renewable energy resources. However, the central role of knowledge...

  19. Electronic Commerce and Electronic Business

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    This special issue is motivated by the recent upsurge of research activity in the areas of electronic commerce and electronic business both in India and all over the world. The current ... Monte Carlo methods for pricing financial options are then.

  20. Electronic Government and Electronic Participation

    NARCIS (Netherlands)

    Tambouris, E; Scholl, H.J.; Janssen, M.F.W.H.A.; Wimmer, M.A.; Tarabanis, K; Gascó, M; Klievink, A.J.; Lindgren, I; Milano, M; Panagiotopoulos, P; Pardo, T.A.; Parycek, P; Sæbø, Ø

    2016-01-01

    Electronic government and electronic participation continue to transform the public sector and society worldwide and are constantly being transformed themselves by emerging information and communication technologies.This book presents papers from the 14th International Federation for Information