Morphological observation and length-weight relationship of critically endangered riverine catfish Rita rita (Hamilton).

Science.gov (United States)

Amin, M R; Mollah, M F A; Taslima, K; Muhammadullah

2014-01-15

The experiment was conducted to investigate the morphological status of the critically endangered riverine catfish Rita rita using morphometric and meristic traits. About 158 species of Rita were collected from the old Brahmaputra river in Mymensingh district and were studied in the laboratory of the Fisheries Biology and Genetics Department, Bangladesh Agricultural University. Measurement of length and weight of Rita were recorded by using measuring scale and electric balance respectively. Significant curvilinear relationship existed between total length and other morphometric characters and between head length and other characters of the head. Relationships between total length and various body measurements of the fish were highly significant (p < 0.01) except the relationship between total length and pelvic fin length of male fish (p < 0.05). In case of meristic characters-dorsal fin rays, pelvic fin rays, pectoral fin rays, anal fin rays, caudal fin rays, number of vertebrae and branchiostegal rays were found to be more or less similar except slight differences. The values of condition factors (k) in the total length body-weight relationships for female and male were found to be 0.41 and 0.38, respectively. The mean values of relative condition factors (kn) were 1.0 and 1.005 for female and male, respectively.

RITA inhibits growth of human hepatocellular carcinoma through induction of apoptosis.

Science.gov (United States)

Wang, Haihe; Chen, Guofu; Wang, Hongzhi; Liu, Chunbo

2013-01-01

RBP-J-interacting and tubulin-associated (RITA) is a novel RBP-J-interacting protein that downregulates Notch-mediated transcription. The current study focuses on the antitumor effect of RITA in human hepatocellular carcinoma (HCC) and aims to explore its molecular mechanism. Thirty paired HCC and adjacent non-tumoral liver samples were analyzed by real-time quantitative reverse transcriptase polymerase chain reaction (qRT-PCR). RITA overexpression was induced by transfection of a pcDNA3.1-Flag-RITA plasmid into HepG2 cells. RITA knockdown was achieved by siRNA transfection. mRNA and protein expression of target genes were quantified by qRT-PCR and Western blotting, respectively. Cell proliferation and apoptosis were measured using MTT assay and flow cytometry. Our results demonstrate that adjacent nontumoral liver samples exhibited increased RITA expression compared to HCC tissues (p RITA levels were associated with tumor differentiation status. Overexpression of RITA suppressed cell proliferation and promoted early apoptosis, while its silencing promoted cell growth dramatically (p RITA overexpression upregulated p53 and reduced cyclin E levels, whereas silencing of RITA had the opposite effect on p53 and cyclin E expression. Our in vitro results represent the first evidence that RITA might suppress tumor growth and induce apoptosis in HCCs, and may be a potent antitumoral agent for HCC treatment that deserves further exploration.

Targeting NF-κB RelA/p65 phosphorylation overcomes RITA resistance.

Science.gov (United States)

Bu, Yiwen; Cai, Guoshuai; Shen, Yi; Huang, Chenfei; Zeng, Xi; Cao, Yu; Cai, Chuan; Wang, Yuhong; Huang, Dan; Liao, Duan-Fang; Cao, Deliang

2016-12-28

Inactivation of p53 occurs frequently in various cancers. RITA is a promising anticancer small molecule that dissociates p53-MDM2 interaction, reactivates p53 and induces exclusive apoptosis in cancer cells, but acquired RITA resistance remains a major drawback. This study found that the site-differential phosphorylation of nuclear factor-κB (NF-κB) RelA/p65 creates a barcode for RITA chemosensitivity in cancer cells. In naïve MCF7 and HCT116 cells where RITA triggered vast apoptosis, phosphorylation of RelA/p65 increased at Ser536, but decreased at Ser276 and Ser468; oppositely, in RITA-resistant cells, RelA/p65 phosphorylation decreased at Ser536, but increased at Ser276 and Ser468. A phosphomimetic mutation at Ser536 (p65/S536D) or silencing of endogenous RelA/p65 resensitized the RITA-resistant cells to RITA while the phosphomimetic mutant at Ser276 (p65/S276D) led to RITA resistance of naïve cells. In mouse xenografts, intratumoral delivery of the phosphomimetic p65/S536D mutant increased the antitumor activity of RITA. Furthermore, in the RITA-resistant cells ATP-binding cassette transporter ABCC6 was upregulated, and silencing of ABCC6 expression in these cells restored RITA sensitivity. In the naïve cells, ABCC6 delivery led to RITA resistance and blockage of p65/S536D mutant-induced RITA sensitivity. Taken together, these data suggest that the site-differential phosphorylation of RelA/p65 modulates RITA sensitivity in cancer cells, which may provide an avenue to manipulate RITA resistance. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

The RITA spectrometer at Risø - design considerations and recent results

Science.gov (United States)

Clausen, K. N.; McMorrow, D. F.; Lefmann, K.; Aeppli, G.; Mason, T. E.; Schröder, A.; Issikii, M.; Nohara, M.; Takagi, H.

In the new cold triple axis spectrometer RITA at Risø we have improved the front end by extensive use of state of the art optical elements and better shielding material. The analyser system is situated in one large open tank and consists of seven individually orientable PG(002) crystal analyser blades, and a 170 mm by 120 mm 2 areas sensitive micro-strip detector. In comparison to the old TAS6 spectrometer we have obtained a factor 2-5 gain in intensity on the sample, a substantially lower background, much more flexibility for optimising the instrument and the possibility to go beyond simple point-by-point inspection. The excellent performance of RITA in the standard TAS mode is exemplified by a study of the dynamics of ≈ 15 nm hematite (α-Fe 2O 3) nano-particles, and utilisation of horizontal and vertical focusing modes to study two dimensional systems is illustrated by a study of the spin fluctuations in the high Tc superconductor La 1.83Sr 0.17CuO 4.

Basic philosophy of the safety design of the Toshiba boiling water reactor

International Nuclear Information System (INIS)

Sato, T.

1992-01-01

This paper discusses the safety design of the Toshiba Boiling Water Reactor (TOSBWR) which was created ∼8 years ago. The design concept is intermediate between conventional boiling water reactors (BWRs) and the advanced BWR (ABWR). It utilizes internal pumps and fine motion control rod drive, but the emergency core cooling system (ECCS) configuration is different from both conventional BWRs and the ABWR. The plant output is 1350 MW (electric). The design is based on two important philosophies: the positive cost reduction philosophy and the constant risk philosophy

Safety design philosophy of gas turbine high temperature reactor (GTHTR300)

International Nuclear Information System (INIS)

Katanishi, Shoji; Kunitomi, Kazuhiko

2003-01-01

Japan Atomic Energy Research Institute has been developing design studies of the Gas Turbine High Temperature Reactor (GTHTR300). The original safety design philosophy has also been discussed and fixed for the GTHTR300. One of the unique feature of the safety philosophy of the GTHTR300 is that a depressurization accident is postulated as a design basis accident in order to show the high level of safety characteristics, though its probability of occurrence is much lower than the probability range of design basis accident. Another feature of safety design is to adopt a double confinement that is one of the original concepts for the GTHTR300. By using a double confinement, a feasibility of safety design without containment vessel was clarified even in case of a depressurization accident. This article describes the safety design philosophy and some results of preliminary evaluations which were conducted in order to clarify the feasibility of original safety design of the GTHTR300. (author)

Engineering Antifragile Systems: A Change In Design Philosophy

Science.gov (United States)

Jones, Kennie H.

2014-01-01

While technology has made astounding advances in the last century, problems are confronting the engineering community that must be solved. Cost and schedule of producing large systems are increasing at an unsustainable rate and these systems often do not perform as intended. New systems are required that may not be achieved by current methods. To solve these problems, NASA is working to infuse concepts from Complexity Science into the engineering process. Some of these problems may be solved by a change in design philosophy. Instead of designing systems to meet known requirements that will always lead to fragile systems at some degree, systems should be designed wherever possible to be antifragile: designing cognitive cyberphysical systems that can learn from their experience, adapt to unforeseen events they face in their environment, and grow stronger in the face of adversity. Several examples are presented of on ongoing research efforts to employ this philosophy.

Deficiency of RITA results in multiple mitotic defects by affecting microtubule dynamics.

Science.gov (United States)

Steinhäuser, K; Klöble, P; Kreis, N-N; Ritter, A; Friemel, A; Roth, S; Reichel, J M; Michaelis, J; Rieger, M A; Louwen, F; Oswald, F; Yuan, J

2017-04-01

Deregulation of mitotic microtubule (MT) dynamics results in defective spindle assembly and chromosome missegregation, leading further to chromosome instability, a hallmark of tumor cells. RBP-J interacting and tubulin-associated protein (RITA) has been identified as a negative regulator of the Notch signaling pathway. Intriguingly, deregulated RITA is involved in primary hepatocellular carcinoma and other malignant entities. We were interested in the potential molecular mechanisms behind its involvement. We show here that RITA binds to tubulin and localizes to various mitotic MT structures. RITA coats MTs and affects their structures in vitro as well as in vivo. Tumor cell lines deficient of RITA display increased acetylated α-tubulin, enhanced MT stability and reduced MT dynamics, accompanied by multiple mitotic defects, including chromosome misalignment and segregation errors. Re-expression of wild-type RITA, but not RITA Δtub ineffectively binding to tubulin, restores the phenotypes, suggesting that the role of RITA in MT modulation is mediated via its interaction with tubulin. Mechanistically, RITA interacts with tubulin/histone deacetylase 6 (HDAC6) and its suppression decreases the binding of the deacetylase HDAC6 to tubulin/MTs. Furthermore, the mitotic defects and increased MT stability are also observed in RITA -/- mouse embryonic fibroblasts. RITA has thus a novel role in modulating MT dynamics and its deregulation results in erroneous chromosome segregation, one of the major reasons for chromosome instability in tumor cells.

Reactivating p53 and Inducing Tumor Apoptosis (RITA) Enhances the Response of RITA-Sensitive Colorectal Cancer Cells to Chemotherapeutic Agents 5-Fluorouracil and Oxaliplatin.

Science.gov (United States)

Wiegering, Armin; Matthes, Niels; Mühling, Bettina; Koospal, Monika; Quenzer, Anne; Peter, Stephanie; Germer, Christoph-Thomas; Linnebacher, Michael; Otto, Christoph

2017-04-01

Colorectal carcinoma (CRC) is the most common cancer of the gastrointestinal tract with frequently dysregulated intracellular signaling pathways, including p53 signaling. The mainstay of chemotherapy treatment of CRC is 5-fluorouracil (5FU) and oxaliplatin. The two anticancer drugs mediate their therapeutic effect via DNA damage-triggered signaling. The small molecule reactivating p53 and inducing tumor apoptosis (RITA) is described as an activator of wild-type and reactivator of mutant p53 function, resulting in elevated levels of p53 protein, cell growth arrest, and cell death. Additionally, it has been shown that RITA can induce DNA damage signaling. It is expected that the therapeutic benefits of 5FU and oxaliplatin can be increased by enhancing DNA damage signaling pathways. Therefore, we highlighted the antiproliferative response of RITA alone and in combination with 5FU or oxaliplatin in human CRC cells. A panel of long-term established CRC cell lines (n=9) including p53 wild-type, p53 mutant, and p53 null and primary patient-derived, low-passage cell lines (n=5) with different p53 protein status were used for this study. A substantial number of CRC cells with pronounced sensitivity to RITA (IC 50 RITA appeared independent of p53 status and was associated with an increase in antiproliferative response to 5FU and oxaliplatin, a transcriptional increase of p53 targets p21 and NOXA, and a decrease in MYC mRNA. The effect of RITA as an inducer of DNA damage was shown by a strong elevation of phosphorylated histone variant H2A.X, which was restricted to RITA-sensitive cells. Our data underline the primary effect of RITA, inducing DNA damage, and demonstrate the differential antiproliferative effect of RITA to CRC cells independent of p53 protein status. We found a substantial number of RITA-sensitive CRC cells within both panels of established CRC cell lines and primary patient-derived CRC cell lines (6/14) that provide a rationale for combining RITA with 5FU or

RITA Mimics: Synthesis and Mechanistic Evaluation of Asymmetric Linked Trithiazoles.

Science.gov (United States)

Pietkiewicz, Adrian L; Zhang, Yuqi; Rahimi, Marwa N; Stramandinoli, Michael; Teusner, Matthew; McAlpine, Shelli R

2017-04-13

The established cytotoxic agent RITA contains a thiophene-furan-thiophene backbone and two terminal alcohol groups. Herein we investigate the effect of using thiazoles as the backbone in RITA-like molecules and modifying the terminal groups of these trithiazoles, thereby generating 41 unique structures. Incorporating side chains with varied steric bulk allowed us to investigate how size and a stereocenter impacted biological activity. Subjecting compounds to growth inhibition assays on HCT-116 cells showed that the most potent compounds 7d , 7e , and 7h had GI 50 values of 4.4, 4.4, and 3.4 μM, respectively, versus RITA (GI 50 of 800 nM). Analysis of these compounds in apoptosis assays proved that 7d , 7e , and 7h were as effective as RITA at inducing apoptosis. Evaluating the impact of 7h on proteins targeted by RITA (p53, c-Myc, and Mcl-1) indicated that it acts via a different mechanism of action to that of RITA. RITA suppressed Mcl-1 protein via p53, whereas compound 7h suppressed Mcl-1 expression via an alternative mechanism independent of p53.

A performance goal-based seismic design philosophy for waste repository facilities

International Nuclear Information System (INIS)

Hossain, Q.A.

1994-02-01

A performance goal-based seismic design philosophy, compatible with DOE's present natural phenomena hazards mitigation and ''graded approach'' philosophy, has been proposed for high level nuclear waste repository facilities. The rationale, evolution, and the desirable features of this method have been described. Why and how the method should and can be applied to the design of a repository facility are also discussed

A performance goal-based seismic design philosophy for waste repository facilities

International Nuclear Information System (INIS)

Hossain, Q.A.

1994-01-01

A performance goal-based seismic design philosophy, compatible with DOE's present natural phenomena hazards mitigation and open-quotes graded approachclose quotes philosophy, has been proposed for high level nuclear waste repository facilities. The rationale, evolution, and the desirable features of this method have been described. Why and how the method should and can be applied to the design of a repository facility are also discussed

Analysis of the interaction between human RITA and Drosophila Suppressor of Hairless.

Science.gov (United States)

Brockmann, Birgit; Mastel, Helena; Oswald, Franz; Maier, Dieter

2014-12-01

Notch signalling mediates intercellular communication, which is effected by the transcription factor CSL, an acronym for vertebrate CBF1/RBP-J, Drosophila Suppressor of Hairless [Su(H)] and C. elegans Lag1. Nuclear import of CBF1/RBP-J depends on co-activators and co-repressors, whereas the export relies on RITA. RITA is a tubulin and CBF1/RBP-J binding protein acting as a negative regulator of Notch signalling in vertebrates. RITA protein is highly conserved in eumatazoa, but no Drosophila homologue was yet identified. In this work, the activity of human RITA in the fly was addressed. To this end, we generated transgenic flies that allow a tissue specific induction of human RITA, which was demonstrated by Western blotting and in fly tissues. Unexpectedly, overexpression of RITA during fly development had little phenotypic consequences, even when overexpressed simultaneously with either Su(H) or the Notch antagonist Hairless. We demonstrate the in vivo binding of human RITA to Su(H) and to tubulin by co-immune precipitation. Moreover, RITA and tubulin co-localized to some degree in several Drosophila tissues. Overall our data show that human RITA, albeit binding to Drosophila Su(H) and tubulin, cannot influence the Notch signalling pathway in the fly, suggesting that a nuclear export mechanism of Su(H), if existent in Drosophila, does not depend on RITA. © 2015 The Authors.

Reactivating p53 and Inducing Tumor Apoptosis (RITA Enhances the Response of RITA-Sensitive Colorectal Cancer Cells to Chemotherapeutic Agents 5-Fluorouracil and Oxaliplatin

Directory of Open Access Journals (Sweden)

Armin Wiegering

2017-04-01

Full Text Available Colorectal carcinoma (CRC is the most common cancer of the gastrointestinal tract with frequently dysregulated intracellular signaling pathways, including p53 signaling. The mainstay of chemotherapy treatment of CRC is 5-fluorouracil (5FU and oxaliplatin. The two anticancer drugs mediate their therapeutic effect via DNA damage-triggered signaling. The small molecule reactivating p53 and inducing tumor apoptosis (RITA is described as an activator of wild-type and reactivator of mutant p53 function, resulting in elevated levels of p53 protein, cell growth arrest, and cell death. Additionally, it has been shown that RITA can induce DNA damage signaling. It is expected that the therapeutic benefits of 5FU and oxaliplatin can be increased by enhancing DNA damage signaling pathways. Therefore, we highlighted the antiproliferative response of RITA alone and in combination with 5FU or oxaliplatin in human CRC cells. A panel of long-term established CRC cell lines (n = 9 including p53 wild-type, p53 mutant, and p53 null and primary patient-derived, low-passage cell lines (n = 5 with different p53 protein status were used for this study. A substantial number of CRC cells with pronounced sensitivity to RITA (IC50< 3.0 μmol/l were identified within established (4/9 and primary patient-derived (2/5 CRC cell lines harboring wild-type or mutant p53 protein. Sensitivity to RITA appeared independent of p53 status and was associated with an increase in antiproliferative response to 5FU and oxaliplatin, a transcriptional increase of p53 targets p21 and NOXA, and a decrease in MYC mRNA. The effect of RITA as an inducer of DNA damage was shown by a strong elevation of phosphorylated histone variant H2A.X, which was restricted to RITA-sensitive cells. Our data underline the primary effect of RITA, inducing DNA damage, and demonstrate the differential antiproliferative effect of RITA to CRC cells independent of p53 protein status. We found a substantial number

Safety design philosophy of gas turbine high temperature reactor (GTHTR300)

International Nuclear Information System (INIS)

Katanishi, Shoji; Kunitomi, Kazuhiko

2003-01-01

Japan Atomic Energy Research Institute (JAERI) has been developing design studies of the Gas Turbine High Temperature Reactor (GTHTR300). The original safety design philosophy has also been discussed and fixed for the GTHTR300 based on the experience of the High Temperature Engineering Test Reactor (HTTR) of JAERI which is the first High Temperature Gas-cooled Reactor (HTGR) in Japan. One of the unique feature of the safety philosophy of the GTHTR300 is that a depressurization accident induced by a large pipe break is postulated as a design basis accident in order to show the high level of safety characteristics, though its probability of occurrence is lower than the probability range of design basis accident. Another feature of safety design is to adopt a double confinement that is one of the original concepts for the GTHTR300. By using a double confinement, a feasibility of safety design without containment vessel was clarified even in case of the depressurization accident. The safety design philosophies for passive cooling system, reactor shutdown system, and so on were determined. The methodology for the safety evaluation, such as safety criteria and selection of events to be evaluated by using estimation of probability of occurrence, were also discussed and determined. This article describes the safety design philosophy and some results of preliminary evaluations which were conducted in order to clarify the feasibility of original safety design of the GTHTR300. The present study is entrusted from Ministry of Education, Culture, Sports, Science and Technology of Japan. (author)

Design matters, and so does philosophy of design : 2003 John Eggleston Memorial Lecture

NARCIS (Netherlands)

Vries, de M.J.

2003-01-01

Why bother about philosophy of design?The theme of the 2003 DATA International Research Conference is ‘Design Matters’. If there is one country in the world that has shown this to be true for design and technology education, it is the UK. Design has had a well established place in general technology

Looking at the future with Rita.

Science.gov (United States)

Bentivoglio, M

2013-11-12

This paper on Rita Levi-Montalcini (1909-2012), who received in 1986 the Nobel Prize in Physiology or Medicine for the discovery of nerve growth factor, focuses on aspects of her advocacy and her commitment to education in which she has been especially active in the last part of her long life. With passionate confidence on the capabilities of the aging brain (together with severe admonition against the pursuit of immortality), she encouraged contributions of senior citizens to the society. Always projected into the future, with enduring faith in the potential of young individuals, in education as a key to development, in the capabilities of women, in the importance of gender equality, Rita established in 2001 the Rita Levi-Montalcini Foundation for the education of African women. Her legacy on engagement for a better 'global village' should not be forgotten by the neuroscience community.

Serous goblet cells: the protein secreting cells in the oral cavity of a catfish, Rita rita (Hamilton, 1822) (Bagridae, Siluriformes).

Science.gov (United States)

Yashpal, Madhu; Mittal, Ajay Kumar

2014-02-01

Serous goblet cells in the oral epithelium of Rita rita are characterized by the presence of distinct eosinophilic granules occupying large parts of the cytoplasm. In R. rita, a range of histochemical results reveal that these cells are involved in proteinaceous secretions, and thus likely contribute to various functions analogous to those of mammalian saliva. The secretions of these cells have also been associated with specific functions and are discussed in relation to their physiological importance with special reference to their roles in lubrication, alteration in viscosity, various functions of mucus such as handling, maneuvering and driving of food items toward the esophagus, maintaining taste sensitivity and protection of the oral epithelium. In addition, the serous goblet cells may also be considered as the primary defensive cell of the oral epithelium of R. rita. The results significantly add to very limited set of literature on the serous goblet cells and provide noteworthy information on the mucous secretions in the oral cavity of fish. Copyright © 2013 Elsevier Ltd. All rights reserved.

RITA: The reinvented triple axis spectrometer

Energy Technology Data Exchange (ETDEWEB)

Mason, T.E. [Toronto Univ., ON (Canada). Dept. of Physics; Clausen, K.N.; Aeppli, G.; McMorrow, D.R.; Kjems, J.K. [Risoe National Lab., Roskilde (Denmark)

1995-11-01

Risoe National Laboratory was reported to be in the process of developing a new spectrometer design, RITA, based on the triple axis design. The spectrometer will attempt to incorporate more recent innovations such as multilayer supermirrors and microstrip proportional counters into a rethinking of the triple-axis spectrometer. By optimizing the beam optics, using supermirrors and extending the analyser to map regions of (Q, {omega}) space using an array of independently controllable pyrolytic graphite crystals focussed on an area detector, it was hoped that the efficiency of single-crystal inelastic experiments could be increased by as much as a factor of 20. 7 figs., 20 refs.

The RITA spectrometer at Risø - Design considerations and recent results

DEFF Research Database (Denmark)

Clausen, K.N.; McMorrow, D.F.; Lefmann, K.

1998-01-01

In the new cold triple axis spectrometer RITA at Riso we have improved the front end by extensive use of state of the art optical elements and better shielding material. The analyser system is situated in one large open tank and consists of seven individually orientable PC(002) crystal analyser b...... by a study of the spin fluctuations in the high T-c superconductor La1.83Sr0.17CuO4. (C) 1998 Elsevier Science B.V. All rights reserved....

Retention of Displaced Students after Hurricanes Katrina and Rita

Science.gov (United States)

Coco, Joshua Christian

2017-01-01

The purpose of the study was to investigate the strategies that university leaders implemented to improve retention of displaced students in the aftermaths of Hurricanes Katrina and Rita. The universities that participated in this study admitted displaced students after Hurricanes Katrina and Rita. This study utilized a qualitative…

RITA displays anti-tumor activity in medulloblastomas independent of TP53 status.

Science.gov (United States)

Gottlieb, Aline; Althoff, Kristina; Grunewald, Laura; Thor, Theresa; Odersky, Andrea; Schulte, Marc; Deubzer, Hedwig E; Heukamp, Lukas; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes H; Künkele, Annette

2017-04-25

Current therapy of medulloblastoma, the most common malignant brain tumor of childhood, achieves 40-70% survival. Secondary chemotherapy resistance contributes to treatment failure, where TP53 pathway dysfunction plays a key role. MDM2 interaction with TP53 leads to its degradation. Reactivating TP53 functionality using small-molecule inhibitors, such as RITA, to disrupt TP53-MDM2 binding may have therapeutic potential. We show here that RITA decreased viability of all 4 analyzed medulloblastoma cell lines, regardless of TP53 functional status. The decrease in cell viability was accompanied in 3 of the 4 medulloblastoma cell lines by accumulation of TP53 protein in the cells and increased CDKN1A expression. RITA treatment in mouse models inhibited medulloblastoma xenograft tumor growth. These data demonstrate that RITA treatment reduces medulloblastoma cell viability in both in vitro and in vivo models, and acts independently of cellular TP53 status, identifying RITA as a potential therapeutic agent to treat medulloblastoma.

[RITA combined with temozolomide inhibits the proliferation of human glioblastoma U87 cells].

Science.gov (United States)

He, Xiao-Yan; Feng, Xiao-Li; Song, Xin-Pei; Zeng, Huan-Chao; Cao, Zhong-Xu; Xiao, Wei-Wei; Zhang, Bao; Wu, Qing-Hua

2016-10-20

To observe the effect of RITA, a small molecule that targets p53, combined with temozolomide (TMZ) on proliferation, colony formation and apoptosis of human glioblastoma U87 cells and explore the underlying mechanism. Cultured U87 cells were treated with RITA (1, 5, 10, 20 µmol/L), TMZ, or RITA+TMZ (half dose) for 24, 48 or 72 h. MTS assay were used to detect the cell proliferation, and the cell proliferation rate and inhibitory rate were calculated. The effect of combined treatments was evaluated by the q value. The expressions of p53, p21 and other apoptosis-associated genes were detected by qRT-PCR and Western blotting; cell apoptosis was assayed using flow cytometry with Annexin V/PI double staining; colony formation of the cells was detected with crystal violet staining. MTS assay showed that RITA at the 4 doses more potently inhibited U87 cell viability than TMZ at 72 h (P=0.000) with inhibitory rates of 25.94%-41.38% and 3.84%-8.20%, respectively. RITA combined with TMZ caused a more significant inhibition of U87 cells (29.21%-52.11%) than RITA (PRITA+TMZ for 48 h resulted in q values exceeding 1.2 and showed an obvious synergistic effect of the drugs. Both RITA and TMZ, especially the latter, significantly increased the expressions of p53, p21, puma, and other apoptosis-associated genes to accelerate apoptosis and inhibit the growth and colony formation of U87 cells, and the effect was more obvious with a combined treatment. RITA inhibits the growth of human glioblastoma cells and enhance their sensitivity to TMZ by up-regulating p53 expression, and when combined, RITA and TMZ show a synergistic effect to cause a stronger cell inhibition.

Interview: Rita Colwell

OpenAIRE

Alucozai, Milad

2012-01-01

Dr. Rita Colwell is a renowned microbiologist and infectious disease expert as well as a Purdue Alumna. She served as the 11th director of the National Science Foundation (NSF) from 1998 to 2004. Currently, she serves as the President and CEO of CosmosID and is a Distinguished Professor at both the University of Maryland and Johns Hopkins University School of Public Health.

The p53-reactivating small molecule RITA induces senescence in head and neck cancer cells.

Science.gov (United States)

Chuang, Hui-Ching; Yang, Liang Peng; Fitzgerald, Alison L; Osman, Abdullah; Woo, Sang Hyeok; Myers, Jeffrey N; Skinner, Heath D

2014-01-01

TP53 is the most commonly mutated gene in head and neck cancer (HNSCC), with mutations being associated with resistance to conventional therapy. Restoring normal p53 function has previously been investigated via the use of RITA (reactivation of p53 and induction of tumor cell apoptosis), a small molecule that induces a conformational change in p53, leading to activation of its downstream targets. In the current study we found that RITA indeed exerts significant effects in HNSCC cells. However, in this model, we found that a significant outcome of RITA treatment was accelerated senescence. RITA-induced senescence in a variety of p53 backgrounds, including p53 null cells. Also, inhibition of p53 expression did not appear to significantly inhibit RITA-induced senescence. Thus, this phenomenon appears to be partially p53-independent. Additionally, RITA-induced senescence appears to be partially mediated by activation of the DNA damage response and SIRT1 (Silent information regulator T1) inhibition, with a synergistic effect seen by combining either ionizing radiation or SIRT1 inhibition with RITA treatment. These data point toward a novel mechanism of RITA function as well as hint to its possible therapeutic benefit in HNSCC.

Digital libraries philosophies, technical design considerations, and example scenarios

CERN Document Server

Stern, David

1999-01-01

An unparalleled overview of current design considerations for your digital library! Digital Libraries: Philosophies, Technical Design Considerations, and Example Scenarios is a balanced overview of public services, collection development, administration, and systems support, for digital libraries, with advice on adopting the latest technologies that appear on the scene. As a professional in the library and information science field, you will benefit from this special issue that serves as an overview of selected directions, trends, possibilities, limitations, enhancements, design principals, an

NASA balloon design and flight - Philosophy and criteria

Science.gov (United States)

Smith, I. S., Jr.

1993-01-01

The NASA philosophy and criteria for the design and flight of scientific balloons are set forth and discussed. The thickness of balloon films is standardized at 20.3 microns to isolate potential film problems, and design equations are given for specific balloon parameters. Expressions are given for: flight-stress index, total required thickness, cap length, load-tape rating, and venting-duct area. The balloon design criteria were used in the design of scientific balloons under NASA auspices since 1986, and the resulting designs are shown to be 95 percent effective. These results represent a significant increase in the effectiveness of the balloons and therefore indicate that the design criteria are valuable. The criteria are applicable to four balloon volume classes in combination with seven payload ranges.

Surface ultrastructure of the gill filaments and the secondary lamellae of the catfish, Rita rita, and the carp, Cirrhinus mrigala.

Science.gov (United States)

Kumari, Usha; Mittal, Swati; Mittal, Ajay Kumar

2012-04-01

Surface ultrastructures of gill filaments and secondary lamellae of Rita rita and Cirrhinus mrigala, inhabiting different ecological habitat, were investigated to unravel adaptive modifications. R. rita is a sluggish, bottom dwelling carnivorous catfish, which inhabits regions of river with accumulations of dirty water. It retains its viability for long time if taken out of water. C. mrigala is an active bottom dwelling Indian major carp, which lives in relatively clean water and dies shortly after taken out of water. In R. rita, gill septa between gill filaments are reduced. Microridges on epithelial cells covering gill filaments are often continuous and arranged concentrically. Secondary lamellae are extensive. The epithelium appears corrugated, show irregular elevations and shallow depressions, and microridges on epithelial cells appear fragmented. In C. mrigala, in contrast, the gill septa are extensive. Microridges on epithelial cells covering gill filaments are fragmented. Secondary lamellae are less extensive. The epithelium appears smooth and microridges on epithelial cells are relatively inconspicuous. These differences have been considered adaptive modification in relation to habit and ecological niches inhabited by two fish species. Presence of mucous goblet cells on gill filaments is discussed in relation to their functions including precipitation of the sediments and preventing clogging of gill filaments. Infrequent mucous goblet cells in the epithelium of secondary lamellae in two fish species are considered an adaptation, minimizing thickness of the epithelium to reduce barrier between blood and water for favoring gasses exchange with increased efficiency. Copyright © 2011 Wiley-Liss, Inc.

The p53-reactivating small molecule RITA induces senescence in head and neck cancer cells.

Directory of Open Access Journals (Sweden)

Hui-Ching Chuang

Full Text Available TP53 is the most commonly mutated gene in head and neck cancer (HNSCC, with mutations being associated with resistance to conventional therapy. Restoring normal p53 function has previously been investigated via the use of RITA (reactivation of p53 and induction of tumor cell apoptosis, a small molecule that induces a conformational change in p53, leading to activation of its downstream targets. In the current study we found that RITA indeed exerts significant effects in HNSCC cells. However, in this model, we found that a significant outcome of RITA treatment was accelerated senescence. RITA-induced senescence in a variety of p53 backgrounds, including p53 null cells. Also, inhibition of p53 expression did not appear to significantly inhibit RITA-induced senescence. Thus, this phenomenon appears to be partially p53-independent. Additionally, RITA-induced senescence appears to be partially mediated by activation of the DNA damage response and SIRT1 (Silent information regulator T1 inhibition, with a synergistic effect seen by combining either ionizing radiation or SIRT1 inhibition with RITA treatment. These data point toward a novel mechanism of RITA function as well as hint to its possible therapeutic benefit in HNSCC.

Rescue of the apoptotic-inducing function of mutant p53 by small molecule RITA.

Science.gov (United States)

Zhao, Carolyn Y; Grinkevich, Vera V; Nikulenkov, Fedor; Bao, Wenjie; Selivanova, Galina

2010-05-01

Expression of mutant p53 correlates with poor prognosis in many tumors, therefore strategies aimed at reactivation of mutant p53 are likely to provide important benefits for treatment of tumors that are resistant to chemotherapy and radiotherapy. We have previously identified and characterized a small molecule RITA which binds p53 and induces a conformational change which prevents the binding of p53 to several inhibitors, including its own destructor MDM2. In this way, RITA rescues the tumor suppression function of wild type p53. Here, we demonstrate that RITA suppressed the growth and induced apoptosis in human tumor cell lines of a diverse origin carrying mutant p53 proteins. RITA restored transcriptional transactivation and transrepression function of several hot spot p53 mutants. The ability of RITA to rescue the activity of different p53 mutants suggests its generic mechanism of action. Thus, RITA is a promising lead for the development of anti-cancer drugs that reactivate the tumor suppressor function of p53 in cancer cells irrespective whether they express mutant or wild type p53.

Rita Kirke: "Taimed on minu head õpetajad ja toetajad" / Rita Kirke

Index Scriptorium Estoniae

Kirke, Rita

2006-01-01

Elukutselisi aiakujundajaid tutvustavas sarjas vastab küsimustele läti aiakujundaja Rita Kirke. R. Kirkest, tema tähtsamad tööd. R. Kirke endast, oma õpetajatest, oma aiast ja töödest, Läti oludesse sobivast ja tüüpilisest Läti aiast, koostööst klientidega, lemmiktaimedest, taimede kättesaadavusest Lätis jpm. Ill.: R. Kirke portreefoto, 6 ill. tema töödest

Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer

Directory of Open Access Journals (Sweden)

Espinoza-Fonseca L Michel

2005-09-01

Full Text Available Abstract Background The use of low-molecular-weight, non-peptidic molecules that disrupt the interaction between the p53 tumor suppressor and its negative regulator MDM2 has provided a promising alternative for the treatment of different types of cancer. Among these compounds, RITA (reactivation of p53 and induction of tumor cell apoptosis has been shown to be effective in the selective induction of apoptosis, and this effect is due to its binding to the p53 tumor suppressor. Since biological systems are highly dynamic and MDM2 may bind to different regions of p53, new alternatives should be explored. On this basis, the computational "blind docking" approach was employed in this study to see whether RITA would bind to MDM2. Results It was observed that RITA binds to the MDM2 p53 transactivation domain-binding cleft. Thus, RITA can be used as a lead compound for designing improved "multi-target" drugs. This novel strategy could provide enormous benefits to enable effective anti-cancer strategies. Conclusion This study has demonstrated that a single molecule can target at least two different proteins related to the same disease.

Self-Knowledge by Proxy: Parsons on Philosophy of Design and the Modernist Vision

Directory of Open Access Journals (Sweden)

Per Galle

Full Text Available Glenn Parsons’s 2016 work, The Philosophy of Design, looks deeply at design in general, and at the Modernist approach to design in particular. The book would make an excellent textbook, but one could equally treat it as a research monograph. This article provides a detailed review of the book as a contribution to design research. The author’s efforts are original and commendable, although the work is not entirely immune to disagreement. The article highlights the main line of reasoning to guide future readers, and develops a number of considerations. These include a reflection on the feasibility of Modernist design thinking, some background on the nature and origins of the philosophy of design as a discipline, a defense of the notion of a stable essence of the concept of design, and a critical analysis of Parsons’s definition of design.

Design process and philosophy of TVA's latest advance control room complex

International Nuclear Information System (INIS)

Owens, G.R.; Masters, D.W.

1979-01-01

TVA's latest nuclear power plant control room design includes a greater emphasis on human factors as compared to their earlier plant designs. This emphasis has resulted in changes in the overall design philosophy and design process. This paper discusses some of the prominent design features of both the control room and the surrounding control room complex. In addition, it also presents some of the important activities involved in the process of developing the advanced control room design

Ang Rita 1

OpenAIRE

Loomis, Molly

2012-01-01

.wav and .mp3 versions of audio file Ang Rita describes in Sherpa difference aspects of his life as a yak herder and yak herding culture. Tape includes native names for yak, birth and death ceremonies; castration practices; differences between Sherpa and Tibetan customs regarding yaks; herding yaks as a child; herding calls; interactions with wolves; grazing practices; concerns about decline of yak herding and the environmental consequences; the future of yak herding; famous yak herders; t...

RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.

Science.gov (United States)

Wacker, Stephan Armin; Alvarado, Cristobal; von Wichert, Götz; Knippschild, Uwe; Wiedenmann, Jörg; Clauss, Karen; Nienhaus, Gerd Ulrich; Hameister, Horst; Baumann, Bernd; Borggrefe, Tilman; Knöchel, Walter; Oswald, Franz

2011-01-05

The evolutionarily conserved Notch signal transduction pathway regulates fundamental cellular processes during embryonic development and in the adult. Ligand binding induces presenilin-dependent cleavage of the receptor and a subsequent nuclear translocation of the Notch intracellular domain (NICD). In the nucleus, NICD binds to the recombination signal sequence-binding protein J (RBP-J)/CBF-1 transcription factor to induce expression of Notch target genes. Here, we report the identification and functional characterization of RBP-J interacting and tubulin associated (RITA) (C12ORF52) as a novel RBP-J/CBF-1-interacting protein. RITA is a highly conserved 36 kDa protein that, most interestingly, binds to tubulin in the cytoplasm and shuttles rapidly between cytoplasm and nucleus. This shuttling RITA exports RBP-J/CBF-1 from the nucleus. Functionally, we show that RITA can reverse a Notch-induced loss of primary neurogenesis in Xenopus laevis. Furthermore, RITA is able to downregulate Notch-mediated transcription. Thus, we propose that RITA acts as a negative modulator of the Notch signalling pathway, controlling the level of nuclear RBP-J/CBF-1, where its amounts are limiting.

A randomized comparison of the Saphenous Vein Versus Right Internal Thoracic Artery as a Y-Composite Graft (SAVE RITA) trial: One-year angiographic results and mid-term clinical outcomes.

Science.gov (United States)

Kim, Ki-Bong; Hwang, Ho Young; Hahn, Seokyung; Kim, Jun Sung; Oh, Se Jin

2014-09-01

The Saphenous Vein Versus Right Internal Thoracic Artery as a Y-Composite Graft (SAVE RITA) trial was designed to evaluate the noninferiority of the saphenous vein (SV) compared with the right internal thoracic artery ([R]ITA) used as a Y-composite graft. A total of 224 patients who had undergone off-pump revascularization for multivessel coronary artery disease using the SV or RITA as a Y-composite graft based on the in situ left ITA were assigned randomly to the SV Y-composite graft (SV group, n = 112) or free RITA Y-composite graft (RITA group, n = 112). The primary endpoint was the 1-year angiographic patency rate of the second limb conduits (SV or RITA). Postoperative 1-year coronary angiograms were performed in 215 patients (SV group, 108; RITA group, 107). The overall graft patency rate was 97.4% (745 of 765) at 1 year (97.9% in the SV group vs 96.9% in the RITA group, P = .362). The primary endpoint of the study, the 1-year patency rate of the SV composite grafts, was 97.1% (238 of 245) and was noninferior to that of the RITA composite grafts (97.1% [198 of 204]) with a 95% lower confidence limit of -2.6% (P RITA composite grafts in terms of the 1-year angiographic patency rates. Copyright © 2014 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

RITA plus 3-MA overcomes chemoresistance of head and neck cancer cells via dual inhibition of autophagy and antioxidant systems.

Science.gov (United States)

Shin, Daiha; Kim, Eun Hye; Lee, Jaewang; Roh, Jong-Lyel

2017-10-01

Reactivation of p53 and induction of tumor cell apoptosis (RITA) is a small molecule that blocks p53-MDM2 interaction, thereby reactivating p53 in tumors. RITA can induce exclusive apoptosis in cancer cells independently of the p53 pathway; however, the resistance of cancer cells remains a major drawback. Here, we found a novel resistance mechanism of RITA treatment and an effective combined treatment to overcome RITA resistance in head and neck cancer (HNC) cells. The effects of RITA and 3-methyladenine (3-MA) were tested in different HNC cell lines, including cisplatin-resistant and acquired RITA-resistant HNC cells. The effects of each drug alone and in combination were assessed by measuring cell viability, apoptosis, cell cycle, glutathione, reactive oxygen species, protein expression, genetic inhibition of p62 and Nrf2, and a mouse xenograft model of cisplatin-resistant HNC. RITA induced apoptosis of HNC cells at different levels without significantly inhibiting normal cell viability. Following RITA treatment, RITA-resistant HNC cells exhibited a sustained expression of other autophagy-related proteins, overexpressed p62, and displayed activation of the Keap1-Nrf2 antioxidant pathway. The autophagy inhibitor 3-MA sensitized resistant HNC cells to RITA treatment via the dual inhibition of molecules related to the autophagy and antioxidant systems. Silencing of the p62 gene augmented the combined effects. The effective antitumor activity of RITA plus 3-MA was also confirmed in vivo in mouse xenograft models transplanted with resistant HNC cells, showing increased oxidative stress and DNA damage. The results indicate that RITA plus 3-MA can help overcome RITA resistance in HNC cells. This study revealed a novel RITA resistant mechanism associated with the sustained induction of autophagy, p62 overexpression, and Keap1-Nrf2 antioxidant system activation. The combined treatment of RITA with the autophagy inhibitor 3-methyladenine overcomes RITA resistance via dual

Prognostic impact of RITA expression in patients with anal squamous cell carcinoma treated with chemoradiotherapy.

Science.gov (United States)

Rödel, Franz; Steinhäuser, Kerstin; Kreis, Nina-Naomi; Friemel, Alexandra; Martin, Daniel; Wieland, Ulrike; Rave-Fränk, Margret; Balermpas, Panagiotis; Fokas, Emmanouil; Louwen, Frank; Rödel, Claus; Yuan, Juping

2018-02-01

RBP-J interacting and tubulin-associated protein (RITA) has been identified as a negative regulator of the Notch signalling pathway and its deregulation is involved in the pathogenesis of several tumour entities. RITA's impact on the response of anal squamous cell carcinoma (SCC) to anticancer treatment, however, remains elusive. In our retrospective study immunohistochemical evaluation of RITA was performed on 140 pre-treatment specimens and was correlated with clinical and histopathologic characteristics and clinical endpoints cumulative incidence of local control (LC), distant recurrence (DC), disease-free survival (DFS) and overall survival (OS). We observed significant inverse correlations between RITA expression and tumour grading, the levels of HPV-16 virus DNA load, CD8 (+) tumour infiltrating lymphocytes and programmed death protein (PD-1) immunostaining. In univariate analyses, elevated levels of RITA expression were predictive for decreased local control (p = 0.001), decreased distant control (p = 0.040), decreased disease free survival (p = 0.001) and overall survival (p RITA expression remained significant for decreased local control (p = 0.009), disease free survival (p = 0.032) and overall survival (p = 0.012). These data indicate that elevated levels of pretreatment RITA expression are correlated with unfavourable clinical outcome in anal carcinoma treated with concomitant chemoradiotherapy. Copyright © 2017 Elsevier B.V. All rights reserved.

Design philosophy of LMFBR steam generator from the viewpoint of maintenance and repair in DeBeNe

International Nuclear Information System (INIS)

Westenbrugge, J.K. van; Dumm, K.

2002-01-01

In this paper we will describe the philosophy as applied in the design of the SNR-300 steam generators and make some remarks on the SNR-2 situation. Topics to be dealt with in design philosophy are: a. system lay-out and component accessibility b. component layout and accessibility to its internals

RITA enhances chemosensivity of pre-B ALL cells to doxorubicin by inducing p53-dependent apoptosis.

Science.gov (United States)

Kazemi, Ahmad; Safa, Majid; Shahbazi, Atefeh

2011-07-01

The use of low-molecular-weight, non-peptidic molecules that disrupt the interaction between the p53 tumor suppressor and its negative regulator MDM2 has provided a promising alternative for the treatment of different types of cancer. Here, we used small-molecule reactivation of p53 and induction of tumor cell apoptosis (RITA) to sensitize leukemic NALM-6 cells to doxorubicin by upregulating p53 protein. RITA alone effectively inhibited NALM-6 cells viability in dose-dependent manner as measured by 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide assay and induced apoptosis as evaluated by flow cytometry, whereas RITA in combination with doxorubicin enhanced NALM-6 cells to doxorubicin-sensitivity and promoted doxorubicin induced apoptosis. Levels of p53 protein and its proapoptotic target genes, quantified by western blot and real-time PCR respectively, showed that expression of p53 was significantly increased after RITA treatment. Using p53 inhibitors PFT-alpha and PFT-mu it was shown that p53-mediated apoptosis induced by RITA can be regulated by both p53-transcription-dependent and -independent pathways. Moreover, RITA-induced apoptosis was accompanied by the activation of caspase-3 and PARP cleavage. Therefore, exploiting synergistic effects between RITA and chemotherapeutics might be an effective clinical strategy for leukemia chemotherapy.

Rita Bottoms: Polyartist Librarian

OpenAIRE

Bottoms, Rita; Reti, Irene; Regional History Project, UCSC Library

2005-01-01

Project Director Irene Reti conducted fourteen hours of interviews with Rita Bottoms, Head of Special Collections at the University Library, UC Santa Cruz, shortly before her retirement in March 2003. This oral history provides a vivid and intimate look at thirty-seven years behind the scenes in the library's Special Collections. For thirty-seven years Bottoms dedicated herself to collecting work by some of the most eminent writers and photographers of the twentieth century, includin...

The p53-reactivating small-molecule RITA enhances cisplatin-induced cytotoxicity and apoptosis in head and neck cancer.

Science.gov (United States)

Roh, Jong-Lyel; Ko, Jung Ho; Moon, Soo Jin; Ryu, Chang Hwan; Choi, Jun Young; Koch, Wayne M

2012-12-01

We evaluated whether the restoration of p53 function by the p53-reactivating small molecule RITA (reactivation of p53 and induction of tumor cell apoptosis enhances cisplatin-induced cytotoxicity and apoptosis in head-and-neck cancer (HNC). RITA induced prominent accumulation and reactivation of p53 in a wild-type TP53-bearing HNC cell line. RITA showed maximal growth suppression in tumor cells showing MDM2-dependent p53 degradation. RITA promoted apoptosis in association with upregulation of p21, BAX, and cleaved caspase-3; notably, the apoptotic response was blocked by pifithrin-α, demonstrating its p53 dependence. With increasing concentrations, RITA strongly induced apoptosis rather than G2-phase arrest. In combination therapy, RITA enhanced cisplatin-induced growth inhibition and apoptosis of HNC cells invitro and in vivo. Our data suggest that the restoration of p53 tumor-suppressive function by RITA enhances the cytotoxicity and apoptosis of cisplatin, an action that may offer an attractive strategy for treating HNC. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Krimmi-Rita juubelituur Eestimaal / Enda Trubok

Index Scriptorium Estoniae

Trubok, Enda

2010-01-01

Kontši-Savva ehk Krasnodarka küla eesti seltsi esinaisel Rita Kadilkinal (neiupõlvenimi Kuusk), kelle esivanemad 1862. aastal Järvamaalt – Albu vallast – Krimmi paremaid maid otsima läksid, täitus septembris 70 eluaastat, mille puhul otsustaski ta Eestisse tulla

Philosophy Rediscovered: Exploring the Connections between Teaching Philosophies, Educational Philosophies, and Philosophy

Science.gov (United States)

Beatty, Joy E.; Leigh, Jennifer S. A.; Dean, Kathy Lund

2009-01-01

Teaching philosophy statements reflect our personal values, connect us to those with shared values in the larger teaching community, and inform our classroom practices. In this article, we explore the often-overlooked foundations of teaching philosophies, specifically philosophy and historical educational philosophies. We review three elements of…

Ambient Assisted Living and ageing: preliminary results of RITA project.

Science.gov (United States)

Aquilano, Michela; Cavallo, Filippo; Bonaccorsi, Manuele; Esposito, Raffaele; Rovini, Erika; Filippi, Massimo; Esposito, Dario; Dario, Paolo; Carrozza, Maria Chiara

2012-01-01

The ageing of population is a social phenomenon that most of worldwide countries are facing. They are, and will be even more in the future, indeed trying to find solutions for improving quality of life of their elderly citizens. The project RITA wants to demonstrate that an update of the current socio-medical services with an Ambient Assisted Living (AAL) approach could improve the service efficiency and the quality of life of both elderly and caregiver. This paper presents the preliminary results obtained in RITA.

Conversacion sobre "Tres tristes tigres". Una entrevista de Rita Guibert (A Conversation about "Three Sad Tigers". An Interview with Rita Guibert)

Science.gov (United States)

Cabrera Infante, Guillermo

1971-01-01

Interview took place in London, England, on October 5, 1970 between Cuban writer Guillermo Cabrera Infante and journalist Rita Guibert. Special issue dedicated to contemporary Spanish American literature. (DS)

Reflection on Lessons Learned: An Analysis of the Adverse Outcomes Observed During the Hurricane Rita Evacuation.

Science.gov (United States)

Baker, Karen

2018-02-01

In September 2005, nearly 3.7 million people evacuated the Texas coastline in advance of Hurricane Rita's landfall, making the event the largest emergency evacuation in US history. The Rita evacuation underscored the importance of planning for domestic mass-evacuation events, as the evacuation itself led to over 100 of the at least 119 deaths attributed to the storm. In the days preceding Rita's landfall, several cascading, interrelated circumstances precipitated such adverse outcomes. This article explores the series of events leading up to the evacuation's poor outcomes, the response following Rita to amend evacuation plans, and how Texas successfully implemented these changes during later storms to achieve better outcomes. (Disaster Med Public Health Preparedness. 2018;12:115-120).

Status of the RITA - experiment on EURECA. [Radio Frequency Ion Thrustor Assembly

Energy Technology Data Exchange (ETDEWEB)

Bassner, H.; Berg, H.P.; Birner, W.; Bartoli, C.; Trippi, A.

1987-01-01

The radiofrequency ion thruster assembly (RITA) is currently built as a flight experiment which shall be flown on the European retrievable carrier (Eureca I). This test flight shall verify the operational use of this electric propulsion system in space by demonstration of operation, lifetime and reliability. For this purpose the RITA experiment has been adapted to meet the specific constraints imposed by the Eureca I spacecraft and by the Space Shuttle as the launcher; xenon gas will be used as the propellant and the experiment will be operated automatically by means of a dedicated on-board microcomputer system. According to the delay in launches by the Space Shuttle the launch date has been postponed from March 1988 to 1991/92. Therefore the total Eureca program has been extended, which also influenced the RITA time schedule.

Philosophy of Interaction

DEFF Research Database (Denmark)

Svanæs, Dag

2011-01-01

This is an encyclopedia entry for the Interaction-Design.org free IxD encyclopedia. The topic of the entry is the application of the philosophy of Heidegger and Merleau-Ponty to a theory of interactivity. Comments by Don Norman and Eva Hornecker.......This is an encyclopedia entry for the Interaction-Design.org free IxD encyclopedia. The topic of the entry is the application of the philosophy of Heidegger and Merleau-Ponty to a theory of interactivity. Comments by Don Norman and Eva Hornecker....

IGF-1R/MDM2 relationship confers enhanced sensitivity to RITA in Ewing sarcoma cells.

Science.gov (United States)

Di Conza, Giusy; Buttarelli, Marianna; Monti, Olimpia; Pellegrino, Marsha; Mancini, Francesca; Pontecorvi, Alfredo; Scotlandi, Katia; Moretti, Fabiola

2012-06-01

Ewing sarcoma is one of the most frequent bone cancers in adolescence. Although multidisciplinary therapy has improved the survival rate for localized tumors, a critical step is the development of new drugs to improve the long-term outcome of recurrent and metastatic disease and to reduce side effects of conventional therapy. Here, we show that the small molecule reactivation of p53 and induction of tumor cell apoptosis (RITA, NSC652287) is highly effective in reducing growth and tumorigenic potential of Ewing sarcoma cell lines. These effects occur both in the presence of wt-p53 as well as of mutant or truncated forms of p53, or in its absence, suggesting the presence of additional targets in this tumor histotype. Further experiments provided evidence that RITA modulates an important oncogenic mark of these cell lines, insulin-like growth factor receptor 1 (IGF-1R). Particularly, RITA causes downregulation of IGF-1R protein levels. MDM2 degradative activity is involved in this phenomenon. Indeed, inhibition of MDM2 function by genetic or pharmacologic approaches reduces RITA sensitivity of Ewing sarcoma cell lines. Overall, these data suggest that in the cell context of Ewing sarcoma, RITA may adopt additional mechanism of action besides targeting p53, expanding its field of application. Noteworthy, these results envisage the promising utilization of RITA or its derivative as a potential treatment for Ewing sarcomas. ©2012 AACR

Lightning and radar observations of hurricane Rita landfall

Energy Technology Data Exchange (ETDEWEB)

Henderson, Bradley G [Los Alamos National Laboratory; Suszcynsky, David M [Los Alamos National Laboratory; Hamlin, Timothy E [Los Alamos National Laboratory; Jeffery, C A [Los Alamos National Laboratory; Wiens, Kyle C [TEXAS TECH U.; Orville, R E [TEXAS A& M

2009-01-01

Los Alamos National Laboratory (LANL) owns and operates an array of Very-Low Frequency (VLF) sensors that measure the Radio-Frequency (RF) waveforms emitted by Cloud-to-Ground (CG) and InCloud (IC) lightning. This array, the Los Alamos Sferic Array (LASA), has approximately 15 sensors concentrated in the Great Plains and Florida, which detect electric field changes in a bandwidth from 200 Hz to 500 kHz (Smith et al., 2002). Recently, LANL has begun development of a new dual-band RF sensor array that includes the Very-High Frequency (VHF) band as well as the VLF. Whereas VLF lightning emissions can be used to deduce physical parameters such as lightning type and peak current, VHF emissions can be used to perform precise 3d mapping of individual radiation sources, which can number in the thousands for a typical CG flash. These new dual-band sensors will be used to monitor lightning activity in hurricanes in an effort to better predict intensification cycles. Although the new LANL dual-band array is not yet operational, we have begun initial work utilizing both VLF and VHF lightning data to monitor hurricane evolution. In this paper, we present the temporal evolution of Rita's landfall using VLF and VHF lightning data, and also WSR-88D radar. At landfall, Rita's northern eyewall experienced strong updrafts and significant lightning activity that appear to mark a transition between oceanic hurricane dynamics and continental thunderstorm dynamics. In section 2, we give a brief overview of Hurricane Rita, including its development as a hurricane and its lightning history. In the following section, we present WSR-88D data of Rita's landfall, including reflectivity images and temporal variation. In section 4, we present both VHF and VLF lightning data, overplotted on radar reflectivity images. Finally, we discuss our observations, including a comparison to previous studies and a brief conclusion.

Wood lens design philosophy based on a binary additive manufacturing technique

Science.gov (United States)

Marasco, Peter L.; Bailey, Christopher

2016-04-01

Using additive manufacturing techniques in optical engineering to construct a gradient index (GRIN) optic may overcome a number of limitations of GRIN technology. Such techniques are maturing quickly, yielding additional design degrees of freedom for the engineer. How best to employ these degrees of freedom is not completely clear at this time. This paper describes a preliminary design philosophy, including assumptions, pertaining to a particular printing technique for GRIN optics. It includes an analysis based on simulation and initial component measurement.

75 FR 14442 - Federal Travel Regulation (FTR); Relocation Allowances-Relocation Income Tax Allowance (RITA) Tables

Science.gov (United States)

2010-03-25

... GENERAL SERVICES ADMINISTRATION [GSA Bulletin FTR 10-04] Federal Travel Regulation (FTR); Relocation Allowances-- Relocation Income Tax Allowance (RITA) Tables AGENCY: Office of Governmentwide Policy... (73 FR 35952) specifying that GSA would no longer publish the RITA tables found in 41 CFR Part 301-17...

Land Area Change and Fractional Water Maps in the Chenier Plain, Louisiana, following Hurricane Rita (2005)

Science.gov (United States)

Palaseanu-Lovejoy, Monica; Kranenburg, Christine J.; Brock, John C.

2010-01-01

In this study, we estimated the changes in land and water coverage of a 1,961-square-kilometer (km2) area in Louisiana's Chenier Plain. The study area is roughly centered on the Sabine National Wildlife Refuge, which was impacted by Hurricane Rita on September 24, 2005. The objective of this study is twofold: (1) to provide pre- and post-Hurricane Rita moderate-resolution (30-meter (m)) fractional water maps based upon multiple source images, and (2) to quantify land and water coverage changes due to Hurricane Rita.

75 FR 7467 - Gary E. Hall and Rita C. Hall; Notice of Application Accepted for Filing With the Commision...

Science.gov (United States)

2010-02-19

... Rita C. Hall; Notice of Application Accepted for Filing With the Commision, Soliciting Motions To.... Project No.: 13652-000. c. Date filed: January 11, 2010. d. Applicant: Gary E. Hall and Rita C. Hall. e... Policies Act of 1978, 16 U.S.C. 2705, 2708. h. Applicant Contact: Mr. Gary E. Hall and Ms. Rita C. Hall, P...

Control room philosophy: Principles of control room design and control room work

International Nuclear Information System (INIS)

Skriver, Jan; Ramberg, Jasmine; Allwin, Pernilla

2006-01-01

In order to provide insights for improvement of work in control rooms several factors have to be considered. Knowledge of principles including control room philosophies will guide the recommended improvements. In addition to knowledge about specific principles an advantage for an organization can be an understanding of similarities and policies used in other high risk industry. The report has been developed on the basis of a document analysis of international standards and other guiding documents. (NUREG 0711, ISO 11064, ISO 6385, IEC 60964). In addition to the document analysis which has strived to compare the documents to see similarities in important principals, experience from working with control room design, modifications and evaluations in other high risk industries has pervaded the report. Important principles have been identified which are recommended to be included in a control room philosophy. Many of these are similar to the principles identified in the international standards. An additional principal which is regarded as important is the utilization of Key Performance Indicators (KPI) which can be used as a measure to target preventative means. Further more it is critical that the control room philosophy is easy to access and comprehend for all users. One of the challenges that remain after having developed a control room philosophy is how to utilize it in the daily work situation. It is vital that the document remains as a living document, guiding the continual improvement of the control room in the various life cycle stages

Philosophy for seismic design of nuclear power plants

International Nuclear Information System (INIS)

Teramae, Tetsuo

1981-01-01

In Japan, earthquakes occur frequently, therefore the basic philosophy in the aseismatic design of nuclear facilities is to design so as not to cause the accident which gives to the public in the surroundings and the employes radiation injuries in the case of large earthquakes. The ''Guideline for the aseismatic design techniques for nuclear power stations'' was drawn up in 1970 as the result of studies by related government offices and organizations. The guideline for determining the earthquakes used for design was published later, and the allowable stress for equipments and pipings has been adopted in accordance with ASME Code, Section 3. The buildings and structures, equipments and pipings in nuclear facilities are classified into three classes according to their importance in aseismatic design. The power of design earthquakes is determined corresponding to the degree of importance. The determination of the standard earthquake waves is explained. The proprieth of aseismatic design is evaluated on the basis of the basic concept of the combination of loads and the allowable limit. The static analysis in accordance with the Building Standards Act is applied to the B and C classes, while the dynamic analysis is required for the A class. The aseismatic analysis of buildings and structures, equipments and pipings is outlined. Many problems to be solved still remain though the concept of aseismatic design has been clarified. (Kako, I.)

Positional stabilization of communications satellites - The RITA ion propulsion system is ready for commercial use

Science.gov (United States)

The radiofrequency ion thruster assembly (RITA) intended for service aboard the new Artemis communications satellite will operate for three hours twice a day, in order to furnish orbital position adjustments that keep antennas accurately pointed toward the earth. These engines are, despite such frequent and sustained use, projected to eject no more than 30 kG of Xe over the course of a decade. RITA operation is also extremely reliable and, due to its very low propellant consumption, is the basis of a long satellite service life. RITA will be among the 15 experiments that are to be performed by ESA's Eureca research satellite.

Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma.

Science.gov (United States)

Saha, Manujendra N; Jiang, Hua; Yang, Yijun; Zhu, Xiaoyun; Wang, Xiaoming; Schimmer, Aaron D; Qiu, Lugui; Chang, Hong

2012-01-01

The low frequency of p53 alterations e.g., mutations/deletions (∼10%) in multiple myeloma (MM) makes this tumor type an ideal candidate for p53-targeted therapies. RITA is a small molecule which can induce apoptosis in tumor cells by activating the p53 pathway. We previously showed that RITA strongly activates p53 while selectively inhibiting growth of MM cells without inducing genotoxicity, indicating its potential as a drug lead for p53-targeted therapy in MM. However, the molecular mechanisms underlying the pro-apoptotic effect of RITA are largely undefined. Gene expression analysis by microarray identified a significant number of differentially expressed genes associated with stress response including c-Jun N-terminal kinase (JNK) signaling pathway. By Western blot analysis we further confirmed that RITA induced activation of p53 in conjunction with up-regulation of phosphorylated ASK-1, MKK-4 and c-Jun. These results suggest that RITA induced the activation of JNK signaling. Chromatin immunoprecipitation (ChIP) analysis showed that activated c-Jun binds to the activator protein-1 (AP-1) binding site of the p53 promoter region. Disruption of the JNK signal pathway by small interfering RNA (siRNA) against JNK or JNK specific inhibitor, SP-600125 inhibited the activation of p53 and attenuated apoptosis induced by RITA in myeloma cells carrying wild type p53. On the other hand, p53 transcriptional inhibitor, PFT-α or p53 siRNA not only inhibited the activation of p53 transcriptional targets but also blocked the activation of c-Jun suggesting the presence of a positive feedback loop between p53 and JNK. In addition, RITA in combination with dexamethasone, known as a JNK activator, displays synergistic cytotoxic responses in MM cell lines and patient samples. Our study unveils a previously undescribed mechanism of RITA-induced p53-mediated apoptosis through JNK signaling pathway and provides the rationale for combination of p53 activating drugs with JNK

Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma.

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Manujendra N Saha

Full Text Available The low frequency of p53 alterations e.g., mutations/deletions (∼10% in multiple myeloma (MM makes this tumor type an ideal candidate for p53-targeted therapies. RITA is a small molecule which can induce apoptosis in tumor cells by activating the p53 pathway. We previously showed that RITA strongly activates p53 while selectively inhibiting growth of MM cells without inducing genotoxicity, indicating its potential as a drug lead for p53-targeted therapy in MM. However, the molecular mechanisms underlying the pro-apoptotic effect of RITA are largely undefined. Gene expression analysis by microarray identified a significant number of differentially expressed genes associated with stress response including c-Jun N-terminal kinase (JNK signaling pathway. By Western blot analysis we further confirmed that RITA induced activation of p53 in conjunction with up-regulation of phosphorylated ASK-1, MKK-4 and c-Jun. These results suggest that RITA induced the activation of JNK signaling. Chromatin immunoprecipitation (ChIP analysis showed that activated c-Jun binds to the activator protein-1 (AP-1 binding site of the p53 promoter region. Disruption of the JNK signal pathway by small interfering RNA (siRNA against JNK or JNK specific inhibitor, SP-600125 inhibited the activation of p53 and attenuated apoptosis induced by RITA in myeloma cells carrying wild type p53. On the other hand, p53 transcriptional inhibitor, PFT-α or p53 siRNA not only inhibited the activation of p53 transcriptional targets but also blocked the activation of c-Jun suggesting the presence of a positive feedback loop between p53 and JNK. In addition, RITA in combination with dexamethasone, known as a JNK activator, displays synergistic cytotoxic responses in MM cell lines and patient samples. Our study unveils a previously undescribed mechanism of RITA-induced p53-mediated apoptosis through JNK signaling pathway and provides the rationale for combination of p53 activating drugs with

Ritacestus gen. n. (Cestoda: Proteocephalidea) and redescription of R. ritaii comb. n., a parasite of Rita rita (Siluriformes) in India.

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de Chambrier, Alain; Scholz, Tomás; Ash, Anirban; Kar, Pradip Kumar

2011-11-01

A new genus, Ritacestus, is proposed to accommodate Ritacestus ritaii (Verma, 1926) comb. n. (syn. Proteocephalus ritaii), a parasite of the catfish Rita rita (Hamilton) in India. The new genus, which is placed in the Gangesiinae, is characterized by (i) a small, subspherical scolex formed by four large lobes separated from one another by longitudinal grooves, with a large, widely oval to pyriform rostellum-like apical organ, larger than suckers and possessing an apical hemispherical depression; (ii) paramuscular and cortical position of some vitelline follicles (most follicles are situated medullary); (iii) ventral and dorsal bands of vitelline follicles usually uninterrupted ventral to terminal genitalia and reaching to the posterior margin of proglottides; (iv) the vagina always anterior to the cirrus-sac; (v) a large size of the body (length up to 51 cm); and (vi) development of the uterus of type 2. In its morphology, especially shape of the scolex and apical organ, and paramuscular and cortical position of some vitelline follicles, Ritacestus resembles Postgangesia Akhmerov, 1969, but differs in the presence of a genital atrium (both genital pores of Postgangesia are separate), the anterior position of the vagina (almost always posterior in the latter genus), position of vitelline follicles in cross sections (dorsal and ventral bands in Ritacestus versus only a lateral band in the latter genus), and dorsal excretory canals indistinguishable in mature and gravid proglottides of R. ritaii (well developed in Postgangesia spp.). The type and only species of the genus, R. ritaii, is redescribed on the basis of new material from the type host from the Ganges River basin in India and its neotype is designated.

Combined VLF and VHF lightning observations of Hurricane Rita landfall

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Henderson, B. G.; Suszcynsky, D. M.; Wiens, K. C.; Hamlin, T.; Jeffery, C. A.; Orville, R. E.

2009-12-01

Hurricane Rita displayed abundant lightning in its northern eyewall as it made landfall at 0740 UTC 24 Sep 2005 near the Texas/Louisiana border. For this work, we combined VHF and VLF lightning data from Hurricane Rita, along with radar observations from Gulf Coast WSR-88D stations, for the purpose of demonstrating the combined utility of these two spectral regions for hurricane lightning monitoring. Lightning is a direct consequence of the electrification and breakdown processes that take place during the convective stages of thunderstorm development. As Rita approached the Gulf coast, the VHF lightning emissions were distinctly periodic with a period of 1.5 to 2 hours, which is consistent with the rotational period of hurricanes. VLF lightning emissions, measured by LASA and NLDN, were present in some of these VHF bursts but not all of them. At landfall, there was a significant increase in lightning emissions, accompanied by a significant convective surge observed in radar. Furthermore, VLF and VHF lightning source heights clearly increase as a function of time. The evolution of the IC/CG ratio is consistent with that seen in thunderstorms, showing a dominance of IC activity during storm development, followed by an increase in CG activity at the storm’s peak. The periodic VHF lightning events are correlated with increases in convective growth (quantified by the volume of radar echo >40 dB) above 7 km altitude. VLF can discriminate between lightning types, and in the LASA data, Rita landfall lightning activity was dominated by Narrow Bi-polar Events (NBEs)—high-energy, high-altitude, compact intra-cloud discharges. The opportunity to locate NBE lightning sources in altitude may be particularly useful in quantifying the vertical extent (strength) of the convective development and in possibly deducing vertical charge distributions.

Structure-function analysis of RBP-J-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genes.

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Tabaja, Nassif; Yuan, Zhenyu; Oswald, Franz; Kovall, Rhett A

2017-06-23

The Notch pathway is a cell-to-cell signaling mechanism that is essential for tissue development and maintenance, and aberrant Notch signaling has been implicated in various cancers, congenital defects, and cardiovascular diseases. Notch signaling activates the expression of target genes, which are regulated by the transcription factor CSL (CBF1/RBP-J, Su(H), Lag-1). CSL interacts with both transcriptional corepressor and coactivator proteins, functioning as both a repressor and activator, respectively. Although Notch activation complexes are relatively well understood at the structural level, less is known about how CSL interacts with corepressors. Recently, a new RBP-J (mammalian CSL ortholog)-interacting protein termed RITA has been identified and shown to export RBP-J out of the nucleus, thereby leading to the down-regulation of Notch target gene expression. However, the molecular details of RBP-J/RITA interactions are unclear. Here, using a combination of biochemical/cellular, structural, and biophysical techniques, we demonstrate that endogenous RBP-J and RITA proteins interact in cells, map the binding regions necessary for RBP-J·RITA complex formation, and determine the X-ray structure of the RBP-J·RITA complex bound to DNA. To validate the structure and glean more insights into function, we tested structure-based RBP-J and RITA mutants with biochemical/cellular assays and isothermal titration calorimetry. Whereas our structural and biophysical studies demonstrate that RITA binds RBP-J similarly to the RAM (RBP-J-associated molecule) domain of Notch, our biochemical and cellular assays suggest that RITA interacts with additional regions in RBP-J. Taken together, these results provide molecular insights into the mechanism of RITA-mediated regulation of Notch signaling, contributing to our understanding of how CSL functions as a transcriptional repressor of Notch target genes. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

RITA plus 3-MA overcomes chemoresistance of head and neck cancer cells via dual inhibition of autophagy and antioxidant systems

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Daiha Shin

2017-10-01

Condensed abstract: This study revealed a novel RITA resistant mechanism associated with the sustained induction of autophagy, p62 overexpression, and Keap1-Nrf2 antioxidant system activation. The combined treatment of RITA with the autophagy inhibitor 3-methyladenine overcomes RITA resistance via dual inhibition of autophagy and antioxidant systems in vitro and in vivo.

44 CFR 206.209 - Arbitration for Public Assistance determinations related to Hurricanes Katrina and Rita (Major...

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2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Arbitration for Public Assistance determinations related to Hurricanes Katrina and Rita (Major disaster declarations DR-1603, DR... determinations related to Hurricanes Katrina and Rita (Major disaster declarations DR-1603, DR-1604, DR-1605, DR...

The philosophy of modelling or does the philosophy of biology have any use?

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Orzack, Steven Hecht

2012-01-19

Biologists in search of answers to real-world issues such as the ecological consequences of global warming, the design of species' conservation plans, understanding landscape dynamics and understanding gene expression make decisions constantly that are based on a 'philosophical' stance as to how to create and test explanations of an observed phenomenon. For better or for worse, some kind of philosophy is an integral part of the doing of biology. Given this, it is more important than ever to undertake a practical assessment of what philosophy does mean and should mean to biologists. Here, I address three questions: should biologists pay any attention to 'philosophy'; should biologists pay any attention to 'philosophy of biology'; and should biologists pay any attention to the philosophy of biology literature on modelling? I describe why the last question is easily answered affirmatively, with the proviso that the practical benefits to be gained by biologists from this literature will be directly proportional to the extent to which biologists understand 'philosophy' to be a part of biology, not apart from biology.

How Schools Responded to Student Mental Health Needs Following Hurricanes Katrina and Rita. Fact Sheet

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RAND Corporation, 2007

2007-01-01

This fact sheet summarizes a study that examined how schools in the U.S. Gulf Coast region perceived the mental health needs of students after Hurricanes Katrina and Rita and how schools responded. According to the report, despite strong initial efforts to support the mental health needs of students displaced by Hurricanes Katrina and Rita, many…

RITA can induce cell death in p53-defective cells independently of p53 function via activation of JNK/SAPK and p38.

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Weilbacher, A; Gutekunst, M; Oren, M; Aulitzky, W E; van der Kuip, H

2014-07-10

Significant advances have been made in the development of small molecules blocking the p53/MDM2 interaction. The Mdm2 inhibitor Nutlin-3 is restricted to tumors carrying wtp53. In contrast, RITA, a compound that binds p53, has recently been shown also to restore transcriptional functions of mtp53. As more than 50% of solid tumors carry p53 mutations, RITA promises to be a more effective therapeutic strategy than Nutlin-3. We investigated effects of RITA on apoptosis, cell cycle and induction of 45 p53 target genes in a panel of 14 cell lines from different tumor entities with different p53 status as well as primary lymphocytes and fibroblasts. Nine cell strains expressed wtp53, four harbored mtp53, and three were characterized by the loss of p53 protein. A significant induction of cell death upon RITA was observed in 7 of 16 cell lines. The nonmalignant cells in our panel were substantially less sensitive. We found that in contrast to Nultin-3, RITA is capable to induce cell death not only in tumor cells harboring wtp53 and mtp53 but also in p53-null cells. Importantly, whereas p53 has a central role for RITA-mediated effects in wtp53 cells, neither p53 nor p63 or p73 were essential for the RITA response in mtp53 or p53-null cells in our panel demonstrating that besides the known p53-dependent action of RITA in wtp53 cells, RITA can induce cell death also independently of p53 in cells harboring defective p53. We identified an important role of both p38 and JNK/SAPK for sensitivity to RITA in these cells leading to a typical caspase- and BAX/BAK-dependent mitochondrial apoptosis. In conclusion, our data demonstrate that RITA can induce apoptosis through p38 and JNK/SAPK not only in tumor cells harboring wtp53 and mtp53 but also in p53-null cells, making RITA an interesting tumor-selective drug.

Der Begriff der Bildung in Deutschland. Zwischen Philosophie und Pädagogik

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Giancarla Sola

2016-07-01

Full Text Available The article ‒ in its five paragraphs, respectively signed by Giancarla Sola, Andreas Dörpinghaus, Egbert Witte, Rita Casale, Jutta Breithausen ‒ represents an endeavor to reconstruct the concept of “Bildung” in Germany. It does this primarily by moving from the meaning that this word has acquired both in the history of Bildung and in the German and “Mittel”-European history. At this glance toward the past, but also threw in the future, as well as in the present, follows an interconnection of relations between Bildung, Empirie and Erfahrung. This last concept places the idea of “experience” in connection with its hermeneutic comprehension. Therefore, the article also thematizes the dialectical legacy of Hegel and Humboldt in the context of the history of German Philosophy and Pedagogy. Then, the article considers the metamorphosis of Bildung after Nationalsozialismus ‒ from 1945 onwards ‒, analyzing the social-economic and political-legal context through the use of a "critics" capable of digging in the relationship between Bildung and Kultur. The article does that focusing, in its final part, on the concept of Widerstreit ‒ "resistance" –, related to a Skepsis understood also as a possible interpretative category of modernity. Thus, the article, in its overall unity, sizing its axial figure ‒ centered on the cultures of Bildung ‒ placing it on the intersecting planes represented by Philosophy and Pedagogy.

Children and Trauma: A Post-Katrina and Rita Response

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Hebert, Barbara B.; Ballard, Mary B.

2007-01-01

Many children have struggled to cope with the traumatic experiences brought about by hurricanes Katrina and Rita. This article recounts how the authors intervened in the lives of children and families after the storms. (Contains 3 figures.)

Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents.

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Michaelis, M; Rothweiler, F; Agha, B; Barth, S; Voges, Y; Löschmann, N; von Deimling, A; Breitling, R; Doerr, H Wilhelm; Rödel, F; Speidel, D; Cinatl, J

2012-04-05

Adaptation of wild-type p53 expressing UKF-NB-3 cancer cells to the murine double minute 2 inhibitor nutlin-3 causes de novo p53 mutations at high frequency (13/20) and multi-drug resistance. Here, we show that the same cells respond very differently when adapted to RITA, a drug that, like nutlin-3, also disrupts the p53/Mdm2 interaction. All of the 11 UKF-NB-3 sub-lines adapted to RITA that we established retained functional wild-type p53 although RITA induced a substantial p53 response. Moreover, all RITA-adapted cell lines remained sensitive to nutlin-3, whereas only five out of 10 nutlin-3-adapted cell lines retained their sensitivity to RITA. In addition, repeated adaptation of the RITA-adapted sub-line UKF-NB-3(r)RITA(10 μM) to nutlin-3 resulted in p53 mutations. The RITA-adapted UKF-NB-3 sub-lines displayed no or less pronounced resistance to vincristine, cisplatin, and irradiation than nutlin-3-adapted UKF-NB-3 sub-lines. Furthermore, adaptation to RITA was associated with fewer changes at the expression level of antiapoptotic factors than observed with adaptation to nutlin-3. Transcriptomic analyses indicated the RITA-adapted sub-lines to be more similar at the gene expression level to the parental UKF-NB-3 cells than nutlin-3-adapted UKF-NB-3 sub-lines, which correlates with the observed chemotherapy and irradiation sensitivity phenotypes. In conclusion, RITA-adapted cells retain functional p53, remain sensitive to nutlin-3, and display a less pronounced resistance phenotype than nutlin-3-adapted cells.

Philosophy, Philosophy of Education, and Economic Realities

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White, John

2013-01-01

In 2009 Harvey Siegel edited "The Oxford Handbook of Philosophy of Education." This article develops a theme, prompted by reflection on several essays in that volume, about the nature of philosophy of education and its relation to philosophy. Siegel's view that philosophy of education is a "branch" of philosophy is put to…

The Recent Infection Testing Algorithm (RITA) in clinical practice: a survey of HIV clinicians in England and Northern Ireland.

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Garrett, Nj; Lattimore, S; Gilbart, Vl; Aghaizu, A; Mensah, G; Tosswill, J; Murphy, G; Delpech, V

2012-08-01

In order to estimate HIV incidence among high-risk groups, in January 2009 the Health Protection Agency introduced the Recent Infection Testing Algorithm (RITA) in England and Northern Ireland (E&NI), currently the only regions to inform patients of RITA results. This survey of HIV specialists aimed to investigate the role of RITA in patient management and explore clinicians' views on its role in clinical practice and during partner notification. An online questionnaire was distributed to HIV specialists via the British HIV Association membership email list in February 2011. Forty-two HIV specialists from 32 HIV centres responded to the survey among 90 centres enrolled in the programme (response rate 36%). Testing for recent infection was considered standard of care by 83% of respondents, 80% felt confident in interpreting results and 92% discussed results with patients, particularly in the context of a possible HIV seroconversion illness (96%) or when deciding when to start antiretroviral therapy (70%). A third (36%) of specialists were initially concerned that RITA results may cause additional anxiety among patients; however, no adverse events were reported. The majority (90%) felt that results could assist with contact tracing by prioritizing patients with likely recent infection. However, only a few centres have currently incorporated RITA into their HIV partner notification protocols. RITA has been introduced into clinical practice with no reported patient adverse events. Access to results at centre level should be improved. National guidance regarding use of RITA as a tool for contact tracing is required. © 2012 British HIV Association.

Planning Beyond Tactics: Towards a Military Application of the Philosophy of Design in the Formulation of Strategy

Science.gov (United States)

2008-05-22

more importantly are, therefore, a priori).63 61 Positivism : The school of philosophy that claims that the only authentic knowledge is that which... quantitative substance to the emerging qualitative ideas. Tactics without Strategy as the Noise Before Defeat. Design is a verb and producing a...interventions, in order to enable the desired potentials that lead to the desired system state. Positivism . The school of philosophy that claims that

SISTEM INFORMASI DAN PENGOLAHAN DATA GAJI KARYAWAN PADA RITA PASARAYA KEBONDALEM PURWOKERTO

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Nyoman Heddy Triyodanta

2009-02-01

Full Text Available Penelitian ini berjudul "Sistem Informasi dan Pengolahan Data GajiKaryawan pada Rita Pasaraya Kebondalem Purwokerto". Tujuan dari penelitian iniodalah untuk mengetahui prosedur sistem informasi pengolahan data gaji karynvanyang sedang berjalan atau sedang dipakai pada Rita Pasaraya KebondalemPurwoketo, yang masih dilakukan dengan proses manual dan pada akhirnyadirancang suatu sistem informasi yang lebih baik. Merancang sistem informasi yangberbasis komputer untuk membantu mengatasi kelemahan dalam pengolahan datamenjadi informasi sesuai dengan kebutuhan user. Hasil analisis menunjukkan bahwapengolahan data di Rita Pasaraya Kebondalem Purwokerto mosih menggunakansistem manual. Sistem yang baru yaitu komputerisasi akan lebih tepat biladipergunakan untuk kehandalan data gaji karyawan. Selain sistem yang baru secarakomputerisasi kedisiplinan pemakai juga perlu ditingkatkan, secara fasilitastambahan selain ruangan khusus yaitu adanya Air Condisioner (AC pada ruangkomputer untuk membuat awet secara perangkat keras komputer dan komputer dapatdihidupkan secara terus menerus. Sistem yang baru aknn menambah kepercayaanImryawan dan pihak lain yang membutuhkan karena akurat, tepat dan handal. Sertapengambilan keputusan tentang kondisi data gaji karyawan dapat lebih alatrat dancepat yang tidak lain dapat meningkatkan kinerja karyawan terhadap perusahaan.

Te Rita Papesch: Case Study of an Exemplary Learner of Maori as an Additional Language

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Ratima, Matiu Tai; Papesch, Te Rita

2014-01-01

This paper presents a case study of the life experiences of one exemplar adult second language Maori learner--Te Rita Papesch. Te Rita was one of 17 participants who were interviewed as a part of the first author's PhD study which sought to answer the question: what factors lead to the development of proficiency in te reo Maori amongst adult…

O Centro Espírita Redemptor e o tratamento de doença mental, 1910-1921 The Centro Espírita Redemptor and the treatment of mental illness, 1910-1921

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André de Faria Pereira Neto

2012-06-01

Full Text Available O espiritismo é uma doutrina religiosa que surgiu na França durante o século XIX por meio da obra de Allan Kardec. No Brasil, assumiu certa originalidade: o espiritismo racional e científico cristão, liderado por Luiz de Mattos, foi uma de suas vertentes doutrinárias nacionais. Luiz de Mattos criou o Centro Espírita Redemptor onde, durante alguns anos, acompanhou o tratamento dos doentes mentais. O artigo analisa as características do tratamento espírita racional e científico cristão à doença mental e as estratégias que Luiz de Mattos adotou para defender sua forma de tratamento. Apresenta ainda algumas semelhanças e diferenças entre o tratamento espírita e o médico.Spiritism is a religious doctrine originated in France during the nineteenth century through the works of Allan Kardec. In Brazil, it assumed an original configuration: rational and scientific Christian spiritism, pioneered by Luiz de Mattos, was one of the national doctrinal variants. Luiz de Mattos created the Centro Espírita Redemptor where, for some years, he monitored the treatment of the mentally ill. The article analyzes the characteristics of rational and scientific Christian spiritism treatment applied to mental illness and the strategies that Luiz de Mattos adopted to defend his form of treatment. Some similarities and differences between spiritist and medical treatment are also outlined.

External factors impacting hospital evacuations caused by Hurricane Rita: the role of situational awareness.

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Downey, Erin L; Andress, Knox; Schultz, Carl H

2013-06-01

The 2005 Gulf Coast hurricane season was one of the most costly and deadly in US history. Hurricane Rita stressed hospitals and led to multiple, simultaneous evacuations. This study systematically identified community factors associated with patient movement out of seven hospitals evacuated during Hurricane Rita. This study represents the second of two systematic, observational, and retrospective investigations of seven acute care hospitals that reported off-site evacuations due to Hurricane Rita. Participants from each hospital included decision makers that comprised the Incident Management Team (IMT). Investigators applied a standardized interview process designed to assess evacuation factors related to external situational awareness of community activities during facility evacuation due to hurricanes. The measured outcomes were responses to 95 questions within six sections of the survey instrument. Investigators identified two factors that significantly impacted hospital IMT decision making: (1) incident characteristics affecting a facility's internal resources and challenges; and (2) incident characteristics affecting a facility's external evacuation activities. This article summarizes the latter and reports the following critical decision making points: (1) Emergency Operations Plans (EOP) were activated an average of 85 hours (3 days, 13 hours) prior to Hurricane Rita's landfall; (2) the decision to evacuate the hospital was made an average of 30 hours (1 day, 6 hours) from activation of the EOP; and (3) the implementation of the evacuation process took an average of 22 hours. Coordination of patient evacuations was most complicated by transportation deficits (the most significant of the 11 identified problem areas) and a lack of situational awareness of community response activities. All evacuation activities and subsequent evacuation times were negatively impacted by an overall lack of understanding on the part of hospital staff and the IMT regarding how to

Damage to offshore infrastructure in the Gulf of Mexico by hurricanes Katrina and Rita

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Cruz, A. M.; Krausmann, E.

2009-04-01

The damage inflicted by hurricanes Katrina and Rita to the Gulf-of-Mexico's (GoM) oil and gas production, both onshore and offshore, has shown the proneness of industry to Natech accidents (natural hazard-triggered hazardous-materials releases). In order to contribute towards a better understanding of Natech events, we assessed the damage to and hazardous-materials releases from offshore oil and natural-gas platforms and pipelines induced by hurricanes Katrina and Rita. Data was obtained through a review of published literature and interviews with government officials and industry representatives from the affected region. We also reviewed over 60,000 records of reported hazardous-materials releases from the National Response Center's (NRC) database to identify and analyze the hazardous-materials releases directly attributed to offshore oil and gas platforms and pipelines affected by the two hurricanes. Our results show that hurricanes Katrina and Rita destroyed at least 113 platforms, and severely damaged at least 53 others. Sixty percent of the facilities destroyed were built 30 years ago or more prior to the adoption of the more stringent design standards that went into effect after 1977. The storms also destroyed 5 drilling rigs and severely damaged 19 mobile offshore drilling units (MODUs). Some 19 MODUs lost their moorings and became adrift during the storms which not only posed a danger to existing facilities but the dragging anchors also damaged pipelines and other infrastructure. Structural damage to platforms included toppling of sections, and tilting or leaning of platforms. Possible causes for failure of structural and non-structural components of platforms included loading caused by wave inundation of the deck. Failure of rigs attached to platforms was also observed resulting in significant damage to the platform or adjacent infrastructure, as well as damage to equipment, living quarters and helipads. The failures are attributable to tie-down components

HTGR safety philosophy

Energy Technology Data Exchange (ETDEWEB)

Joksimovic, V.; Fisher, C. R. [General Atomic Co., San Diego, CA (USA)

1981-01-15

The accident at the Three Mile Island has focused public attention on reactor safety. Many public figures advocate a safer method of generating nuclear electricity for the second nuclear era in the U.S. The paper discusses the safety philosophy of a concept deemed suitable for this second nuclear era. The HTGR, in the course of its evolution, included safety as a significant determinant in design philosophy. This is particularly evident in the design features which provide inherent safety. Inherent features cause releases from a wide spectrum of accident conditions to be low. Engineered features supplement inherent features. The significance of HTGR safety features is quantified and order-of-magnitude type of comparisons are made with alternative ways of generating electricity.

HTGR safety philosophy

International Nuclear Information System (INIS)

Joksimovic, V.; Fisher, C.R.

1981-01-01

The accident at the Three Mile Island has focused public attention on reactor safety. Many public figures advocate a safer method of generating nuclear electricity for the second nuclear era in the U.S. The paper discusses the safety philosophy of a concept deemed suitable for this second nuclear era. The HTGR, in the course of its evolution, included safety as a significant determinant in design philosophy. This is particularly evident in the design features which provide inherent safety. Inherent features cause releases from a wide spectrum of accident conditions to be low. Engineered features supplement inherent features. The significance of HTGR safety features is quantified and order-of-magnitude type of comparisons are made with alternative ways of generating electricity. (author)

HTGR safety philosophy

International Nuclear Information System (INIS)

Joskimovic, V.; Fisher, C.R.

1980-08-01

The accident at the Three Mile Island has focused public attention on reactor safety. Many public figures advocate a safer method of generating nuclear electricity for the second nuclear era in the US. The paper discusses the safety philosophy of a concept deemed suitable for this second nuclear era. The HTGR, in the course of its evolution, included safety as a significant determinant in design philosophy. This is particularly evident in the design features which provide inherent safety. Inherent features cause releases from a wide spectrum of accident conditions to be low. Engineered features supplement inherent features. The significance of HTGR safety features is quantified and order-of-magnitude type of comparisons are made with alternative ways of generating electricity

Philosophy of Science and Philosophy of Chemistry

OpenAIRE

Jaap van Brakel

2014-01-01

In this paper I assess the relation between philosophy of chemistry and (general) philosophy of science, focusing on those themes in the philosophy of chemistry that may bring about major revisions or extensions of current philosophy of science. Three themes can claim to make a unique contribution to philosophy of science: first, the variety of materials in the (natural and artificial) world; second, extending the world by making new stuff; and, third, specific features of the relations betwe...

Measuring philosophy: a philosophy index

OpenAIRE

Biggs, Lesley; Mierau, Dale; Hay, David

2002-01-01

Chiropractic philosophy which has been debated since the founding of chiropractic in 1895 has taken on new vigour over the past ten years. Despite a growing body of literature examining chiropractic philosophy, the chiropractic profession continues to be divided over this issue. To date, there has been little research examining the meaning of chiropractic philosophy to rank-and-file practitioners.

Shelf sediment transport during hurricanes Katrina and Rita

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Xu, Kehui; Mickey, Rangley C.; Chen, Qin; Harris, Courtney K.; Hetland, Robert D.; Hu, Kelin; Wang, Jiaze

2016-05-01

Hurricanes can greatly modify the sedimentary record, but our coastal scientific community has rather limited capability to predict hurricane-induced sediment deposition. A three-dimensional sediment transport model was developed in the Regional Ocean Modeling System (ROMS) to study seabed erosion and deposition on the Louisiana shelf in response to Hurricanes Katrina and Rita in the year 2005. Sensitivity tests were performed on both erosional and depositional processes for a wide range of erosional rates and settling velocities, and uncertainty analysis was done on critical shear stresses using the polynomial chaos approximation method. A total of 22 model runs were performed in sensitivity and uncertainty tests. Estimated maximum erosional depths were sensitive to the inputs, but horizontal erosional patterns seemed to be controlled mainly by hurricane tracks, wave-current combined shear stresses, seabed grain sizes, and shelf bathymetry. During the passage of two hurricanes, local resuspension and deposition dominated the sediment transport mechanisms. Hurricane Katrina followed a shelf-perpendicular track before making landfall and its energy dissipated rapidly within about 48 h along the eastern Louisiana coast. In contrast, Hurricane Rita followed a more shelf-oblique track and disturbed the seabed extensively during its 84-h passage from the Alabama-Mississippi border to the Louisiana-Texas border. Conditions to either side of Hurricane Rita's storm track differed substantially, with the region to the east having stronger winds, taller waves and thus deeper erosions. This study indicated that major hurricanes can disturb the shelf at centimeter to meter levels. Each of these two hurricanes suspended seabed sediment mass that far exceeded the annual sediment inputs from the Mississippi and Atchafalaya Rivers, but the net transport from shelves to estuaries is yet to be determined. Future studies should focus on the modeling of sediment exchange between

Santa Rita Experimental Range digital database: user's guide

Science.gov (United States)

Mitchel P. McClaran; Deborah L. Angell; Craig Wissler

2002-01-01

Long-term measurements and repeat photograph collections have been collected in a systematic manner on the approximately 21,000 ha Santa Rita Experimental Range (SRER) since its establishment in 1903. This research facility, located in the Desert Grassland vegetation of southern Arizona, was administered by the U.S. Department of Agriculture until 1988, when it was...

Advanced Neutron Source operating philosophy

International Nuclear Information System (INIS)

Houser, M.M.

1993-01-01

An operating philosophy and operations cost estimate were prepared to support the Conceptual Design Report for the Advanced Neutron Source (ANS), a new research reactor planned for the Oak Ridge National Laboratory (ORNL). The operating philosophy was part of the initial effort of the ANS Human Factors Program, was integrated into the conceptual design, and addressed operational issues such as remote vs local operation; control room layout and responsibility issues; role of the operator; simulation and training; staffing levels; and plant computer systems. This paper will report on the overall plans and purpose for the operations work, the results of the work done for conceptual design, and plans for future effort

Facility design philosophy: Tank Waste Remediation System Process support and infrastructure definition

International Nuclear Information System (INIS)

Leach, C.E.; Galbraith, J.D.; Grant, P.R.; Francuz, D.J.; Schroeder, P.J.

1995-11-01

This report documents the current facility design philosophy for the Tank Waste Remediation System (TWRS) process support and infrastructure definition. The Tank Waste Remediation System Facility Configuration Study (FCS) initially documented the identification and definition of support functions and infrastructure essential to the TWRS processing mission. Since the issuance of the FCS, the Westinghouse Hanford Company (WHC) has proceeded to develop information and requirements essential for the technical definition of the TWRS treatment processing programs

Resilience of Professional Counselors Following Hurricanes Katrina and Rita

Science.gov (United States)

Lambert, Simone F.; Lawson, Gerard

2013-01-01

Professional counselors who provided services to those affected by Hurricanes Katrina and Rita completed the K6+ (screen for severe mental illness), the Posttraumatic Growth Inventory, and the Professional Quality of Life Scale. Results indicated that participants who survived the hurricanes had higher levels of posttraumatic growth than…

Developing a computer-based environment for the design of nuclear power plants: a perspective and philosophy

International Nuclear Information System (INIS)

Brey, H.; Kisner, R.A.

1985-08-01

This report surveys the usefulness and general design requirements for a large-scale database and database manager for design and analysis of nuclear power plant control systems. The control engineer's and systems integrator's need for timely, accurate, and searchable information for advanced control system design increases with competitive economics and stringent reliability demands. A philosophy is conveyed for the implementation of an integrated, comprehensive database system

RITA inhibits multiple myeloma cell growth through induction of p53-mediated caspase-dependent apoptosis and synergistically enhances nutlin-induced cytotoxic responses.

Science.gov (United States)

Saha, Manujendra N; Jiang, Hua; Mukai, Asuka; Chang, Hong

2010-11-01

Mutations or deletions of p53 are relatively rare in multiple myeloma (MM), at least in newly diagnosed patients. Thus, restoration of p53 tumor suppressor function in MM by blocking the inhibitory role of murine double minute 2 (MDM2) is a promising and applicable therapeutic strategy. RITA and nutlin are two new classes of small molecule MDM2 inhibitors that prevent the p53-MDM2 interaction. Earlier reports showed p53-dependent activity of RITA in solid tumors as well as in leukemias. We and others recently described nutlin-induced apoptosis in MM cells, but it remains unclear whether RITA exerts antimyeloma activity. Here, we found that RITA activates the p53 pathway and induces apoptosis in MM cell lines and primary MM samples, preferentially killing myeloma cells. The activation of p53 induced by RITA was mediated through modulation of multiple apoptotic regulatory proteins, including upregulation of a proapoptotic protein (NOXA), downregulation of an antiapoptotic protein, Mcl-1, and activation of caspases through extrinsic pathways. Moreover, a number of key p53-mediated apoptotic target genes were identified by gene expression profiling and further validated by quantitative real-time PCR. Importantly, the combination of RITA with nutlin displayed a strong synergism on growth inhibition with the combination index ranging from 0.56 to 0.82 in MM cells. Our data support further clinical evaluation of RITA as a potential novel therapeutic intervention in MM. ©2010 AACR.

Recognizing history in range ecology: 100 years of science and management on the Santa Rita Experimental Range

Science.gov (United States)

Nathan F. Sayre

2003-01-01

At the centennial of the Santa Rita Experimental Range, historical analysis is called for on two levels. First, as a major site in the history of range ecology, the Santa Rita illuminates past successes and failures in science and management and the ways in which larger social, economic, and political factors have shaped scientific research. Second, with the turn away...

Rita Lobato: a primeira médica formada no Brasil

Directory of Open Access Journals (Sweden)

Francisco Bruno Lobo

2017-04-01

Dentre elas foi escolhida a primeira mulher que se diplomou em medicina em uma Faculdade brasileira: A Dra. Rita Lobato de Freitas . No dia 9 de junho, aniversário de seu nascimento, o referido sêlo entrou em circulação.

Metal concentrations in schoolyard soils from New Orleans, Louisiana before and after Hurricanes Katrina and Rita.

Science.gov (United States)

Presley, Steven M; Abel, Michael T; Austin, Galen P; Rainwater, Thomas R; Brown, Ray W; McDaniel, Les N; Marsland, Eric J; Fornerette, Ashley M; Dillard, Melvin L; Rigdon, Richard W; Kendall, Ronald J; Cobb, George P

2010-06-01

The long-term environmental impact and potential human health hazards resulting from Hurricanes Katrina and Rita throughout much of the United States Gulf Coast, particularly in the New Orleans, Louisiana, USA area are still being assessed and realized after more than four years. Numerous government agencies and private entities have collected environmental samples from throughout New Orleans and found concentrations of contaminants exceeding human health screening values as established by the United States Environmental Protection Agency (USEPA) for air, soil, and water. To further assess risks of exposure to toxic concentrations of soil contaminants for citizens, particularly children, returning to live in New Orleans following the storms, soils collected from schoolyards prior to Hurricane Katrina and after Hurricane Rita were screened for 26 metals. Concentrations exceeding USEPA Regional Screening Levels (USEPA-RSL), total exposure, non-cancer endpoints, for residential soils for arsenic (As), iron (Fe), lead (Pb), and thallium (Tl) were detected in soil samples collected from schoolyards both prior to Hurricane Katrina and after Hurricane Rita. Approximately 43% (9/21) of schoolyard soils collected prior to Hurricane Katrina contained Pb concentrations greater than 400mgkg(-1), and samples from four schoolyards collected after Hurricane Rita contained detectable Pb concentrations, with two exceeding 1700mgkg(-1). Thallium concentrations exceeded USEPA-RSL in samples collected from five schoolyards after Hurricane Rita. Based upon these findings and the known increased susceptibility of children to the effects of Pb exposure, a more extensive assessment of the soils in schoolyards, public parks and other residential areas of New Orleans for metal contaminants is warranted. 2010 Elsevier Ltd. All rights reserved.

RITA enhances irradiation-induced apoptosis in p53-defective cervical cancer cells via upregulation of IRE1α/XBP1 signaling.

Science.gov (United States)

Zhu, Hong; Abulimiti, Muyasha; Liu, Huan; Su, Xiang-Jiang; Liu, Cai-Hong; Pei, Hai-Ping

2015-09-01

Radiation therapy is the most widely used treatment for patients with cervical cancer. Recent studies have shown that endoplasmic reticulum (ER) stress induces apoptosis and sensitizes tumor cells to radiotherapy, which reportedly induces ER stress in cells. Classical key tumor suppressor p53 is involved in the response to a variety of cellular stresses, including those incurred by ionizing irradiation. A recent study demonstrated that small-molecule RITA (reactivation of p53 and induction of tumor cell apoptosis) increased the radiosensitivity of tumor cells expressing mutant p53 (mtp53). In the present study, we explored the effects and the underlying mechanisms of RITA in regards to the radiosensitivity and ER stress in mtp53-expressing human cervix cancer cells. Treatment with 1 µM of RITA for 24 h before irradiation markedly decreased survival and increased apoptosis in C-33A and HT-3 cells; the effects were not significantly altered by knockdown of p53. In the irradiated C-33A and HT-3 cells, RITA significantly increased the expression of IRE1α, the spliced XBP1 mRNA level, as well as apoptosis; the effects were abolished by knockdown of IRE1α. Transcriptional pulse-chase assays revealed that RITA significantly increased the stability of IRE1α mRNA in the irradiated C-33A and HT-3 cells. In contrast, the same RITA treatment did not show any significant effect on sham-irradiated cells. In conclusion, the present study provides initial evidence that RITA upregulates the expression level of IRE1α by increasing the stability of IRE1α mRNA in irradiated mtp53-expressing cervical cancer cells; the effect leads to enhanced IRE1α/XBP1 ER stress signaling and increased apoptosis in the cells. The present study offers novel insight into the pharmacological potential of RITA in the radiotherapy for cervical cancer.

John White on Philosophy of Education and Philosophy

Science.gov (United States)

Siegel, Harvey

2014-01-01

John White offers a provocative characterization of philosophy of education. In this brief reaction, I evaluate the characterization and urge the maintenance of a strong connection between philosophy of education and philosophy.

History, applications, and philosophy in mathematics education

DEFF Research Database (Denmark)

Jankvist, Uffe Thomas

2013-01-01

on the observation that a use of history, applications, and philosophy as a 'goal' is best realized through a modules approach, the article goes on to discuss how to actually design such teaching modules. It is argued that a use of primary original sources through a so-called guided reading along with a use......The article first investigates the basis for designing teaching activities dealing with aspects of history, applications, and philosophy of mathematics in unison by discussing and analyzing the different 'whys' and 'hows' of including these three dimensions in mathematics education. Based...... of student essay assignments, which are suitable for bringing out relevant meta-issues of mathematics, is a sensible way of realizing a design encompassing the three dimensions. Two concrete teaching modules on aspects of the history, applications, and philosophy of mathematics-HAPh-modules-are outlined...

The changing shape of U.S. licensing philosophy

International Nuclear Information System (INIS)

Remick, F.J.

1992-01-01

The shape of U.S. nuclear licensing and regulatory philosophy and process has already changed. The new process requires NRC review and approval of the vendor designs before a prospective utility license applicant purchases the design and begins construction. The new philosophy has resulted from the lessons learned from extensive operating experience accumulated in the United States. New criteria established for judging reactor designs include the capability of future designs to be more tolerant of accidents beyond the traditional design basis events. Qualitative and quantitative goals have been chosen as a guide for allocating resources for regulation of the currently operating plants. The changing shape of nuclear licensing and regulatory philosophy is also a result of economic circumstances in the United States. All will have a better opportunity to take part in the process which is most likely to encourage further development of safe nuclear energy in the United States. (author)

Efficient synthesis of RITA and its analogues: derivation of analogues with improved antiproliferative activity via modulation of p53/miR-34a pathway.

Science.gov (United States)

Lin, Jinshun; Jin, Xiuli; Bu, Yiwen; Cao, Deliang; Zhang, Nannan; Li, Shangfu; Sun, Qinsheng; Tan, Chunyan; Gao, Chunmei; Jiang, Yuyang

2012-12-28

A novel approach to synthesize RITA by practical palladium-catalyzed C-C bond-forming Suzuki reactions at room temperature was developed, which was used for deriving a series of substituted tricyclic α-heteroaryl (furan/thiophene) analogues of RITA under mild conditions. These novel analogues showed notable antiproliferative activity against cancer cell lines with wild-type p53 (i.e., HCT116, A549, MCF-7 and K562), but much less activity in HCT116/p53(-/-) cells. In particular, compound 1f demonstrated promising antiproliferative activity compared to RITA, with IC(50) = 28 nM in MCF-7 vs. 54 nM for RITA, and cancer cell selectivity. Compound 1f markedly activated p53 in HCT116 cells at 100 nM, triggering apoptosis. Importantly, we found that both RITA and compound 1f induced G(0)/G(1) cell cycle arrest by up-regulating miR-34a, which in turn down-regulated the expression of cell cycle-related proteins CDK4 and E2F1. In summary, this study reports an effective synthetic approach for RITA and its analogues, and elucidates a novel antiproliferative mechanism of these compounds.

Rescue of p53 function by small-molecule RITA in cervical carcinoma by blocking E6-mediated degradation.

Science.gov (United States)

Zhao, Carolyn Ying; Szekely, Laszlo; Bao, Wenjie; Selivanova, Galina

2010-04-15

Proteasomal degradation of p53 by human papilloma virus (HPV) E6 oncoprotein plays a pivotal role in the survival of cervical carcinoma cells. Abrogation of HPV-E6-dependent p53 destruction can therefore be a good strategy to combat cervical carcinomas. Here, we show that a small-molecule reactivation of p53 and induction of tumor cell apoptosis (RITA) is able to induce the accumulation of p53 and rescue its tumor suppressor function in cells containing high-risk HPV16 and HPV18 by inhibiting HPV-E6-mediated proteasomal degradation. RITA blocks p53 ubiquitination by preventing p53 interaction with E6-associated protein, required for HPV-E6-mediated degradation. RITA activates the transcription of proapoptotic p53 targets Noxa, PUMA, and BAX, and repressed the expression of pro-proliferative factors CyclinB1, CDC2, and CDC25C, resulting in p53-dependent apoptosis and cell cycle arrest. Importantly, RITA showed substantial suppression of cervical carcinoma xenografts in vivo. These results provide a proof of principle for the treatment of cervical cancer in a p53-dependent manner by using small molecules that target p53. (c)2010 AACR.

p53-dependent inhibition of TrxR1 contributes to the tumor-specific induction of apoptosis by RITA.

Science.gov (United States)

Hedström, Elisabeth; Eriksson, Sofi; Zawacka-Pankau, Joanna; Arnér, Elias S J; Selivanova, Galina

2009-11-01

Thioredoxin reductase 1 (TrxR1) is a key regulator in many redox-dependent cellular pathways, and is often overexpressed in cancer. Several studies have identified TrxR1 as a potentially important target for anticancer therapy. The low molecular weight compound RITA (NSC 652287) binds p53 and induces p53-dependent apoptosis. Here we found that RITA also targets TrxR1 by non-covalent binding, followed by inhibition of its activity in vitro and by inhibition of TrxR activity in cancer cells. Interestingly, a novel approximately 130 kDa form of TrxR1, presumably representing a stable covalently linked dimer, and an increased generation of reactive oxygen species (ROS) were induced by RITA in cancer cells in a p53-dependent manner. Similarly, the gold-based TrxR inhibitor auranofin induced apoptosis related to oxidative stress, but independently of p53 and without apparent induction of the approximately 130 kDa form of TrxR1. In contrast to the effects observed in cancer cells, RITA did not inhibit TrxR or ROS formation in normal fibroblasts (NHDF). The inhibition of TrxR1 can sensitize tumor cells to agents that induce oxidative stress and may directly trigger cell death. Thus, our results suggest that a unique p53-dependent effect of RITA on TrxR1 in cancer cells might synergize with p53-dependent induction of pro-apoptotic genes and oxidative stress, thereby leading to a robust induction of cancer cell death, without affecting non-transformed cells.

Lightcurves for Shape Modeling: 852 Wladilena, 1089 Tama, and 1180 Rita

Science.gov (United States)

Polishook, David

2012-10-01

The folded lightcurves and synodic periods of 852 Wladilena, 1089 Tama, and 1180 Rita are reported. The data are used by Hanus et al. (2012) to derive the rotation axis and to construct a shape model by applying the inversion lightcurve technique.

Damage-tolerant design and inspection philosophy for nuclear and other pressure vessels

International Nuclear Information System (INIS)

Adams, N.J.I.

1980-01-01

Statistical analyses of pressure vessel failure rates indicate that, to date, the record is very good. However, the public hazard and environmental consequences of failure in certain industrial processes now give cause for much greater concern. With the exception of an Appendix in ASME III, the current design codes and requirements for new vessels are all based on the assumption that they are free from cracklike defects, but engineers recognize tht such perfect vessels cannot be manufactured. Taking into account failure mechanisms, material properties, pre- and in-service inspection, proof testing, failure statistics and probabilistic methods, views are put forward on how a damage-tolerant design and inspection philosophy may be developed to reduce further the possibility of ''rogue'' vessel failure. 21 refs

87 Philosophy and African Philosophy: A Conceptual Analysis ...

African Journals Online (AJOL)

Tracie1

concepts of philosophy and then African philosophy. This is because the ... philosophy inter alia, as one's moral guide is only but the informal meaning ... reasons for all the assumptions entertained by any disciplines. .... quite unfortunate to state here that the earliest studies and .... functionality, rigour and coherence. And as ...

A Green Prison: The Santa Rita Jail Campus Microgrid

Energy Technology Data Exchange (ETDEWEB)

Marnay, Chris; DeForest, Nicholas; Lai, Judy

2012-01-22

A large microgrid project is nearing completion at Alameda County’s twenty-two-year-old 45 ha 4,000-inmate Santa Rita Jail, about 70 km east of San Francisco. Often described as a green prison, it has a considerable installed base of distributed energy resources (DER) including an eight-year old 1.2 MW PV array, a five-year old 1 MW fuel cell with heat recovery, and considerable efficiency investments. A current US$14 M expansion adds a 2 MW-4 MWh Li-ion battery, a static disconnect switch, and various controls upgrades. During grid blackouts, or when conditions favor it, the Jail can now disconnect from the grid and operate as an island, using the on-site resources described together with its back-up diesel generators. In other words, the Santa Rita Jail is a true microgrid, or μgrid, because it fills both requirements, i.e. it is a locally controlled system, and it can operate both grid connected and islanded. The battery’s electronics includes Consortium for Electric Reliability Technology (CERTS) Microgrid technology. This enables the battery to maintain energy balance using droops without need for a fast control system.

Introduction: philosophy in and philosophy of cognitive science.

Science.gov (United States)

Brook, Andrew

2009-04-01

Despite being there from the beginning, philosophical approaches have never had a settled place in cognitive research and few cognitive researchers not trained in philosophy have a clear sense of what its role has been or should be. We distinguish philosophy in cognitive research and philosophy of cognitive research. Concerning philosophy in cognitive research, after exploring some standard reactions to this work by nonphilosophers, we will pay particular attention to the methods that philosophers use. Being neither experimental nor computational, they can leave others bewildered. Thought experiments are the most striking example but not the only one. Concerning philosophy of cognitive research, we will pay particular attention to its power to generate and test normative claims, claims about what should and should not be done. Copyright © 2009 Cognitive Science Society, Inc.

Opening Philosophy to the World: Derrida and Education in Philosophy

Science.gov (United States)

Burik, Steven

2009-01-01

In this essay, Steven Burik discusses Jacques Derrida's position with regard to the place of education in philosophy within the university system, and then relates these thoughts to comparative philosophy. Philosophers find themselves constantly having to defend philosophy and the importance of teaching philosophy against pressure from the powers…

Swamp tours in Louisiana post Hurricane Katrina and Hurricane Rita

Science.gov (United States)

Dawn J. Schaffer; Craig A. Miller

2007-01-01

Hurricanes Katrina and Rita made landfall in southern Louisiana during August and September 2005. Prior to these storms, swamp tours were a growing sector of nature-based tourism that entertained visitors while teaching about local flora, fauna, and culture. This study determined post-hurricane operating status of tours, damage sustained, and repairs made. Differences...

Effects of hurricanes Katrina and Rita on the chemistry of bottom sediments in Lake Pontchartrain, Louisiana, USA

Science.gov (United States)

Van Metre, P.C.; Horowitz, A.J.; Mahler, B.J.; Foreman, W.T.; Fuller, C.C.; Burkhardt, M.R.; Elrick, K.A.; Furlong, E.T.; Skrobialowski, S.C.; Smith, J.J.; Wilson, J.T.; Zaugg, S.D.

2006-01-01

The effects of Hurricanes Katrina and Rita and the subsequent unwatering of New Orleans, Louisiana, on the sediment chemistry of Lake Pontchartrain were evaluated by chemical analysis of samples of street mud and suspended and bottom sediments. The highest concentrations of urban-related elements and compounds (e.g., Pb, Zn, polycyclic aromatic hydrocarbons, and chlordane) in bottom sediments exceeded median concentrations in U.S. urban lakes and sediment-quality guidelines. The extent of the elevated concentrations was limited, however, to within a few hundred meters of the mouth of the 17th Street Canal, similar to results of historical assessments. Chemical and radionuclide analysis of pre- and post-Hurricane Rita samples indicates that remobilization of near-shore sediment by lake currents and storms is an ongoing process. The effects of Hurricanes Katrina and Rita on the sediment chemistry of Lake Pontchartrain are limited spatially and are most likely transitory. ?? 2006 American Chemical Society.

Geology of Santa Rita Coal Basin, Rio Grande do Sul, Brazil

Energy Technology Data Exchange (ETDEWEB)

Correa da Silva, Z.C.; Bortoluzzi, C.A.; Cazzulo-Klepzig, M.; Dias-Fabricio, M.E.; Guerra-Sommer, M.; Marques-Toigo, M.; Paim, P.S.G.; Piccoli, A.E.M.; Silva Filho, B.C.

1984-04-01

Data on the sedimentology, stratigraphy, palynology, coal petrography and geochemistry of the Santa Rita Coal Basin, Rio Grande do Sul, Brazil, are presented. The investigations were carried out on samples obtained from drill cores of the sedimentary rocks of Tubarao Supergroup, Lower Permian of Parana Basin. (25 refs.)

Philosophy for nuclear thermal propulsion

International Nuclear Information System (INIS)

Buden, D.; Madsen, W.; Redd, L.

1993-01-01

The philosophy used for development of nuclear thermal propulsion will determine the cost, schedule and risk associated with the activities. As important is the impression of the decision makers. If the development cost is higher than the product value, it is doubtful that funding will ever be available. On the other hand, if the development supports the economic welfare of the country with a high rate of return, the probability of funding greatly increases. The philosophy is divided into: realism, design, operations and qualification. ''Realism'' addresses such items as political acceptability, potential customers, robustness-flexibility, public acceptance, decisions as needed, concurrent engineering, and the possible role of the CIS. ''Design'' addresses ''minimum requirement,'' built in safety and reliability redundancy, emphasize on eliminating risk at lowest levels, and the possible inclusion of electric generation. ''Operations'' addresses sately, environment, operations, design margins and degradation modes. ''Qualification'' addresses testing needs and test facilities

Safety philosophy and design principles for systems and components of nuclear power plant: external event

International Nuclear Information System (INIS)

Lopes, J.P.G.

1986-01-01

In nuclear power plants, some systems and components are designed to withstand external impacts. Such systems and components are those which have to perform their functions even during and after the occurrences of an earthquake, for example, fulfilling the safety objectives and avoiding the release of radioactive material to the environment. The aim of this report is to introduce the safety philosophy and design principles for systems/components to perform their functions during and after the occurrence of an earthquake, as applied by NUCLEN for Angra 2 and 3. (Author) [pt

Sir John and Lady Rita Cornforth: a distinguished chemical partnership.

Science.gov (United States)

Purchase, Rupert; Hanson, James R

2015-01-01

This review describes the life of Sir John Cornforth AC CBE FRS, who was awarded the Nobel Prize for Chemistry in 1975. It covers his early life in Australia, his work in Oxford, the National Institute for Medical Research, the Milstead Laboratory of Chemical Enzymology and the University of Sussex, together with the contributions made by his wife, Lady Rita Cornforth.

Integration& Operation of a Microgrid at Santa Rita Jail

Energy Technology Data Exchange (ETDEWEB)

Chevron Energy Solutions; Alameda County; DeForest, Nicholas; Lai, Judy; Stadler, Michael; Mendes, Goncalo; Marnay, Chris; Donadee, Jon

2011-05-01

Santa Rita Jail is a 4,500 inmate facility located in Dublin CA, approximately 40 miles (65 km) east of San Francisco. Over the past decade, a series of Distributed Energy Resources (DER) installations and efficiency measures have been undertaken to transform the 3MW facility into a"Green Jail". These include a 1.2MW rated rooftop PV system installed in 2002, a 1MW molten carbonate fuel cell with CHP, and retrofits to lighting and HVAC systems to reduce peak loads. With the upcoming installation of a large-scale battery and fast static disconnect switch, Santa Rita Jail will become a true microgrid, with full CERTS Microgrid functionality. Consequently, the jail will be able to seamlessly disconnect from the grid and operate as an island in the event of a disturbance, reconnecting again once the disturbance has dissipated. The extent to which that jail is capable of islanding is principally dependant on the energy capacity of the battery-one focus of this investigation. Also presented here are overviews of the DER currently installed at the jail, as well as the value it provides by offsetting the purchase of electricity under the current Pacific Gas& Electric (PG&E) tariff.

Educational Non-Philosophy

Science.gov (United States)

Cole, David R.

2015-01-01

The final lines of Deleuze and Guattari's What is Philosophy? call for a non-philosophy to balance and act as a counterweight to the task of philosophy that had been described by them in terms of concept creation. In a footnote, Deleuze and Guattari mention François Laruelle's project of non-philosophy, but dispute its efficacy in terms of the…

Secondary eyewall formation in WRF simulations of Hurricanes Rita and Katrina (2005)

Science.gov (United States)

Abarca, Sergio F.; Corbosiero, Kristen L.

2011-04-01

An analysis is presented of two high-resolution hurricane simulations of Katrina and Rita (2005) that exhibited secondary eyewall formation (SEF). The results support the notion of vortex Rossby waves (VRWs) having an important role in SEF and suggest that VRW activity is a defining aspect of the moat. SEF occurs at a radius of ˜65 (80) km in Katrina (Rita), close to the hypothesized stagnation radius of VRWs. VRW activity appears to be the result of eye-eyewall mixing events, themselves a product of the release of barotropic instability. The convection in the radial region that becomes the moat is mainly in the form of VRWs propagating radially outward from the primary eyewall until the negative radial gradient of potential vorticity is no longer conducive for their propagation. These convectively coupled waves, originating and being expelled from the eyewall, are rotation dominated and have the coherency necessary to survive their passage through the strain-dominated region outside the eyewall.

Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu).

Science.gov (United States)

Luan, Jinwei; Li, Xianglan; Guo, Rutao; Liu, Shanshan; Luo, Hongyu; You, Qingshan

2016-06-01

Next generation sequencing and bio-informatic analyses were conducted to investigate the mechanism of reactivation of p53 and induction of tumor cell apoptosis (RITA)-enhancing X-ray susceptibility in FaDu cells. The cDNA was isolated from FaDu cells treated with 0 X-ray, 8 Gy X-ray, or 8 Gy X-ray + RITA. Then, cDNA libraries were created and sequenced using next generation sequencing, and each assay was repeated twice. Subsequently, differentially expressed genes (DEGs) were identified using Cuffdiff in Cufflinks and their functions were predicted by pathway enrichment analyses. Genes that were constantly up- or down-regulated in 8 Gy X-ray-treated FaDu cells and 8 Gy X-ray + RITA-treated FaDu cells were obtained as RITA genes. Afterward, the protein-protein interaction (PPI) relationships were obtained from the STRING database and a PPI network was constructed using Cytoscape. Furthermore, ClueGO was used for pathway enrichment analysis of genes in the PPI network. Total 2,040 and 297 DEGs were identified in FaDu cells treated with 8 Gy X-ray or 8 Gy X-ray + RITA, respectively. PARP3 and NEIL1 were enriched in base excision repair, and CDK1 was enriched in p53 signaling pathway. RFC2 and EZH2 were identified as RITA genes. In the PPI network, many interaction relationships were identified (e.g., RFC2-CDK1, EZH2-CDK1 and PARP3-EZH2). ClueGO analysis showed that RFC2 and EZH2 were related to cell cycle. RFC2, EZH2, CDK1, PARP3 and NEIL1 may be associated, and together enhance the susceptibility of FaDu cells treated with RITA to the deleterious effects of X-ray.

Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu)

International Nuclear Information System (INIS)

Luan, Jinwei; Li, Xianglan; Guo, Rutao; Liu, Shanshan; Luo, Hongyu; You, Qingshan

2016-01-01

Next generation sequencing and bio-informatic analyses were conducted to investigate the mechanism of reactivation of p53 and induction of tumor cell apoptosis (RITA)-enhancing X-ray susceptibility in FaDu cells. The cDNA was isolated from FaDu cells treated with 0 X-ray, 8 Gy X-ray, or 8 Gy X-ray + RITA. Then, cDNA libraries were created and sequenced using next generation sequencing, and each assay was repeated twice. Subsequently, differentially expressed genes (DEGs) were identified using Cuffdiff in Cufflinks and their functions were predicted by pathway enrichment analyses. Genes that were constantly up- or down-regulated in 8 Gy X-ray-treated FaDu cells and 8 Gy X-ray + RITA-treated FaDu cells were obtained as RITA genes. Afterward, the protein-protein interaction (PPI) relationships were obtained from the STRING database and a PPI network was constructed using Cytoscape. Furthermore, ClueGO was used for pathway enrichment analysis of genes in the PPI network. Total 2,040 and 297 DEGs were identified in FaDu cells treated with 8 Gy X-ray or 8 Gy X-ray + RITA, respectively. PARP3 and NEIL1 were enriched in base excision repair, and CDK1 was enriched in p53 signaling pathway. RFC2 and EZH2 were identified as RITA genes. In the PPI network, many interaction relationships were identified (e.g., RFC2-CDK1, EZH2-CDK1 and PARP3-EZH2). ClueGO analysis showed that RFC2 and EZH2 were related to cell cycle. RFC2, EZH2, CDK1, PARP3 and NEIL1 may be associated, and together enhance the susceptibility of FaDu cells treated with RITA to the deleterious effects of X-ray

On Performative Philosophy – 10 impulses for discussion from [soundcheck philosophie

Directory of Open Access Journals (Sweden)

Eva Maria Gauß

2015-04-01

Full Text Available Since 2011, the philosophy-performance festival, [soundcheck philosophie] has been gathering protagonists in German-speaking countries, who seek and intend to cultivate a certain practice in philosophy. This practice takes philosophy - focussing not only on written texts but also on the fundamental oral situations that take place within pilosophy - and presents it artistically and/or through media. In this context. The term ‘Performative Philosophy’ is meant as a working concept for finding criteria and developing contemporary expressions and forms of doing pilosophy. The [soundcheck philosophie] festival and the association responsible for it, Expedition Philosophie / Internationale Gesellschaft für Performative Philosophie, are understood as a forum for discourse. The 10 theses at the end of this article are intended to initiate discussion. Informed by the well-known yet unique structure of an oral conversation, where a lot of things are mentioned out of context and the topic often remains to be discovered, we would also like to contribute impulses for conversation. With this in mind, we have incorporated 10 conversational impulses that answer, tell, ask, state, chat, riddle and reflect about the undertaking of the project of Performative Philosophy.

The Impact of Hurricanes Katrina and Rita on Louisiana School Nurses

Science.gov (United States)

Broussard, Lisa; Myers, Rachel; Meaux, Julie

2008-01-01

In the fall of 2005, the coast of Louisiana was devastated by two hurricanes, Katrina and Rita. Not only did these natural disasters have detrimental effects for those directly in their path, the storms had an impact on the lives of everyone in Louisiana. The professional practice of many Louisiana school nurses was affected by several factors,…

Philosophy at Cambridge, Newsletter of the Faculty of Philosophy

OpenAIRE

Lecky-Thompson, Jenni

2009-01-01

Philosophy Newsletter. Articles by: Edward Craig - From the Chairman. Onora O'Neill - "It's the newspapers I can't stand. Serena Olsaretti - The 2004 Annual Royal Institute of Philosophy Conference. Mary Leng - Mathematical Knowledge Conference. Postgraduate Conference. Jane Heal - Facts, Fables and Funds. Hugh Mellor - Uses and Abuses of Probability. Amanda Boyle - Nobody Knows Anything: Philosophy, Film and Me. Jaime Whyte - Seven Years at Cambridge Alex Oliver...

The provenance and Sm/Nd Model ages of siliciclastic supracrustal rocks of the Faina and Santa Rita Greenstone belts, Goias, Brazil; Proveniencia e idades modelo Sm/Nd das rochas siliciclasticas arqueanas dos greenstone belts de Faina e Santa Rita, Goias

Energy Technology Data Exchange (ETDEWEB)

Resende, Marcelo Goncalves [Universidade Catolica de Brasilia, DF (Brazil); Jost, Hardy [Brasilia Univ., DF (Brazil). Inst. de Geociencias; Lima, Bruno Eustaquio Moreira; Teixeira, Alexandre de Amorim

1999-09-01

The Faina and Santa Rita greenstone belts are two N 60 deg C W trending synclinoria separated by a N 30 deg C E strike-slip fault and rest allochtonous on the adjacent Uva and Caicara granite-gneiss complexes. The belts are made up of lower metakomatiites, followed by metabasalts and thick metasedimentary sequences deposited under contrasting paleogeographic settings. In Faina, the sequence consists of two complete shelf cycles, the first resting on basalts by an erosional unconformity. In Santa Rita, the basalts give gradually place to carbonaceous metashales, unconformably overlain by metarhythmites. Provenance based on trace element geochemistry, mineral chemistry of chloride and muscovite, source-are modeling and REE elements indicate that protoliths of the first shelf cycle of Faina and the carbonaceous metashales of Santa Rita formed under the influence of a source area dominated by mafic ultramafic rocks, whilst during the sedimentation of the second shelf cycle and the metarhythmites of Santa Rita the source-area was dominated by TTG granitoids. Sm-Nd model ages of the lower sedimentary packages vary between 3.0 and 2.8 Ga and the upper between 2.7 and 2.6 Ga. These intervals coincide, respectively, with the estimated age of the underlying, and with the Sm-Nd, Rb-Sr e U-Pb ages of the main granitoids and gneisses of the adjacent complexes. The same data indicate that, during the sedimentation of the first shelf cycle of Faina and the carbonaceous metashales of Santa Rita, both basins had independent source-areas, but shared the same source during the upper sections. Weathering nature and intensity of the source-area calculated by means of geochemical a data suggest that the dramatic change of provenance from the lower to the upper sections is due to the shift from tectonically stable to unstable regimes, interpreted as resulting from the emergence of the island arc whose roots are represented by the adjacent granite-gneiss complexes. (author)

Philosophy of Information: Revolution in Philosophy. Towards an Informational Metaphilosophy of Science

Directory of Open Access Journals (Sweden)

Kun Wu

2017-10-01

Full Text Available In the most general if unconventional terms, science is the study of how man is part of the universe. Philosophy is the study of man’s ideas of the universe and how man differs from the rest of the universe. It has of course been recognized that philosophy and science are not totally disjointed. Science is in any case not a monolithic entity but refers to knowledge as the results of reasoning and both invasive and non-invasive experiment. We argue that the philosophy of science, in studying the foundations, methods and implications of science and the link between philosophy and science, must now take into account the impact of the rapidly developing science and philosophy of information. We suggest that the philosophy of information is in fact a metaphilosophy, since informational processes operate in all the sciences and their philosophies. The simplest definition of (a metaphilosophy is that of a set of statements about (a philosophy, and any definition of a metaphilosophy thus requires one of philosophy and of the task of philosophy as well. According to Sellars, “the aim of philosophy is to understand how things in the broadest possible sense of the term hang together in the broadest possible sense of the term”. In this paper, we focus on the recursive thought underlying those statements as real processes, occurring both in and between the fundamental and the meta-level. We propose a non-standard logic, Logic in Reality, as the logic of those processes. The metaphilosophy of information is thus a framework for talking about the scientific aspects of philosophy and the philosophical aspects of science. Both Logic in Reality and the metaphilosophy of information provide a basis for understanding the physical and epistemological dynamics of existence, that is, from where the properties of things come that enable both them and the concepts of them to contrast, conflict and ultimately “hang together”. We conclude that the current

Philosophy and safety requirements for land-based nuclear installations

International Nuclear Information System (INIS)

Kellermann, Otto

1978-01-01

The main ideas of safety philosophy for land-based nuclear installations are presented together with their background of protection goals. Today's requirements for design and quality assurance are deductively shown. Finally a proposition is made for a new balancing of safety philosophy according to the high safety level that nuclear installations have reached

Philosophy and Politics: The anti-political character of Socrates’ philosophy and Plato ’s project of making philosophy political

OpenAIRE

Hrvoje Cvijanović

2016-01-01

The intention of this research is to elaborate on Socrates’ philosophy and its serious consequences for the relationship between philosophy and politics, hence making them hostile to each other, and Socrates an enemy of the people. The author explores the tension between philosophy and public life by comparing and contrasting two opposing philosophical projects – Socrates and Plato’s – while illuminating different methods and paths they follow in their understanding of philosophy and politics...

A Kiss Lajos-díj 2016. évi nyertese: dr. Póczos Rita [Winner of the 2016 Lajos Kiss Prize: Dr Rita Póczos

Directory of Open Access Journals (Sweden)

Hoffmann, István

2016-12-01

Full Text Available The Lajos Kiss Prize, awarded every two or three years since 2006, is considered to be a highly prestigious award for young onomasticians. The 2016 winner of the prize is Dr Rita Póczos, senior lecturer at the Department of Hungarian Linguistics of the University of Debrecen. She was given this award for her contribution to Hungarian Historical Onomastics, especially for her research on place names.

Is Philosophy of Education a Historical Mistake? Connecting Philosophy and Education Differently

Science.gov (United States)

Biesta, Gert

2014-01-01

In this article, I suggest that the question whether the proper place for philosophy of education is in the domain of philosophy or the domain of education cannot be resolved as long as we think of the connection between philosophy and education in terms of the idea of "philosophy of education". To substantiate this point, I look into…

Pharmacological targeting of p53 through RITA is an effective antitumoral strategy for malignant pleural mesothelioma.

Science.gov (United States)

Di Marzo, Domenico; Forte, Iris Maria; Indovina, Paola; Di Gennaro, Elena; Rizzo, Valeria; Giorgi, Francesca; Mattioli, Eliseo; Iannuzzi, Carmelina Antonella; Budillon, Alfredo; Giordano, Antonio; Pentimalli, Francesca

2014-01-01

Malignant mesothelioma, a very aggressive tumor associated to asbestos exposure, is expected to increase in incidence, and unfortunately, no curative modality exists. Reactivation of p53 is a new attractive antitumoral strategy. p53 is rarely mutated in mesothelioma, but it is inactivated in most tumors by the lack of p14(ARF). Here, we evaluated the feasibility of this approach in pleural mesothelioma by testing RITA and nutlin-3, two molecules able to restore p53 function through a different mechanism, on a panel of mesothelioma cell lines representing the epithelioid (NCI-H28, NCI-H2452, IST-MES 2), biphasic (MSTO-211H), and sarcomatoid (NCI-H2052) histotypes compared with the normal mesothelial HMC-hTERT. RITA triggered robust caspase-dependent apoptosis specifically in epithelioid and biphasic mesothelioma cell lines, both through wild-type and mutant p53, concomitant to p21 downregulation. Conversely, nutlin-3 induced a p21-dependent growth arrest, rather than apoptosis, and was slightly toxic on HMC-hTERT.   Interestingly, we identified a previously undetected point mutation of p53 (p.Arg249Ser) in IST-MES 2, and showed that RITA is also able to reactivate this p53 mutant protein and its apoptotic function. RITA reduced tumor growth in a MSTO-211H-derived xenograft model of mesothelioma and synergized with cisplatin, which is the mainstay of treatment for this tumor. Our data indicate that reactivation of p53 and concomitant p21 downregulation effectively induce cell death in mesothelioma, a tumor characterized by a high intrinsic resistance to apoptosis. Altogether, our findings provide the preclinical framework supporting the use of p53-reactivating agents alone, or in combination regimens, to improve the outcome of patients with mesothelioma.

My Teaching Learning Philosophy

Science.gov (United States)

Punjani, Neelam Saleem

2014-01-01

The heart of teaching learning philosophy is the concept of nurturing students and teaching them in a way that creates passion and enthusiasm in them for a lifelong learning. According to Duke (1990) education is a practice of artful action where teaching learning process is considered as design and knowledge is considered as colours. Teaching…

Effects of marsh pond terracing on coastal wintering waterbirds before and after Hurricane Rita.

Science.gov (United States)

O'Connell, Jessica L; Nyman, John A

2011-11-01

From February to March 2005-2006, we surveyed wintering waterbirds to test effects of terracing on coastal pond use before and after Hurricane Rita. Marsh terracing is intended to slow coastal marsh loss in the Chenier Plain by slowing marsh erosion and encouraging vegetation expansion. Terraces also increase marsh edge in ponds, possibly benefiting waterbirds. We monitored paired terraced and unterraced ponds in three sites within southwestern Louisiana's Chenier Plain. Waterbirds were 75% more numerous in terraced than unterraced ponds. Waterbird richness was similar among ponds when corrected for number of individuals, suggesting terracing increased bird density but did not provide habitat unique from unterraced ponds. Birds were 93% more numerous following Hurricane Rita, mostly due to an influx of migrating waterfowl. Year round residents were similar in number before and after Hurricane Rita. Resident richness did not differ among years after correcting for number of observed individuals. Wading and dabbling foragers were more abundant in terraced ponds and these two guilds represented 74% of birds observed. We detected no difference among ponds for other guilds, i.e., probing, aerial, and diving foragers. Increasing proportion of mash edge increased bird density disproportionately: On average ponds with 10% edge had 6 birds observed and ponds with 30% edge had 16 birds observed. Terraces increased habitat interspersion and were an effective tool for increasing numbers of wintering waterfowl and wading birds. The extent to which terraces were sustainable following hurricane forces is unknown.

Effects of Marsh Pond Terracing on Coastal Wintering Waterbirds Before and After Hurricane Rita

Science.gov (United States)

O'Connell, Jessica L.; Nyman, John A.

2011-11-01

From February to March 2005-2006, we surveyed wintering waterbirds to test effects of terracing on coastal pond use before and after Hurricane Rita. Marsh terracing is intended to slow coastal marsh loss in the Chenier Plain by slowing marsh erosion and encouraging vegetation expansion. Terraces also increase marsh edge in ponds, possibly benefiting waterbirds. We monitored paired terraced and unterraced ponds in three sites within southwestern Louisiana's Chenier Plain. Waterbirds were 75% more numerous in terraced than unterraced ponds. Waterbird richness was similar among ponds when corrected for number of individuals, suggesting terracing increased bird density but did not provide habitat unique from unterraced ponds. Birds were 93% more numerous following Hurricane Rita, mostly due to an influx of migrating waterfowl. Year round residents were similar in number before and after Hurricane Rita. Resident richness did not differ among years after correcting for number of observed individuals. Wading and dabbling foragers were more abundant in terraced ponds and these two guilds represented 74% of birds observed. We detected no difference among ponds for other guilds, i.e., probing, aerial, and diving foragers. Increasing proportion of mash edge increased bird density disproportionately: On average ponds with 10% edge had 6 birds observed and ponds with 30% edge had 16 birds observed. Terraces increased habitat interspersion and were an effective tool for increasing numbers of wintering waterfowl and wading birds. The extent to which terraces were sustainable following hurricane forces is unknown.

Development of a nuclear ship safety philosophy

International Nuclear Information System (INIS)

Thompson, T.E.

1978-01-01

A unique safety philosophy must be recognized and accepted as an integral part of the design and operation of a nuclear ship. For the nuclear powered ship, the ultimate safety of the reactor and therefore the crew and the environment lies with the safety of the ship itself. The basis for ship safety is its ability to navigate and survive the conditions or the environment in which it may find itself. The subject of traditional ship safety is examined along with its implication for reactor protection and safety. Concepts of reactor safety are also examined. These two philosophies are combined in a manner so as to provide a sound philosophy for the safety of nuclear ships, their crews, and the environment

The death of Philosophy: A response to Stephen Hawking | Scott ...

African Journals Online (AJOL)

In his 2010 work, The Grand Design, Stephen Hawking, argues that '… philosophy is dead' (2010: 5). While not a Philosopher, Hawking provides strong argument for his thesis, principally that philosophers have not taken science sufficiently seriously and so Philosophy is no longer relevant to knowledge claims.

Control room philosophy: Principles of control room design and control room work; Kontrollrumsfilosofi: Principer foer kontrollrumsutformning och kontrollrumsarbete

Energy Technology Data Exchange (ETDEWEB)

Skriver, Jan; Ramberg, Jasmine; Allwin, Pernilla [Scandpower Risk Management AB, Uppsala (Sweden)

2006-01-15

In order to provide insights for improvement of work in control rooms several factors have to be considered. Knowledge of principles including control room philosophies will guide the recommended improvements. In addition to knowledge about specific principles an advantage for an organization can be an understanding of similarities and policies used in other high risk industry. The report has been developed on the basis of a document analysis of international standards and other guiding documents. (NUREG 0711, ISO 11064, ISO 6385, IEC 60964). In addition to the document analysis which has strived to compare the documents to see similarities in important principals, experience from working with control room design, modifications and evaluations in other high risk industries has pervaded the report. Important principles have been identified which are recommended to be included in a control room philosophy. Many of these are similar to the principles identified in the international standards. An additional principal which is regarded as important is the utilization of Key Performance Indicators (KPI) which can be used as a measure to target preventative means. Further more it is critical that the control room philosophy is easy to access and comprehend for all users. One of the challenges that remain after having developed a control room philosophy is how to utilize it in the daily work situation. It is vital that the document remains as a living document, guiding the continual improvement of the control room in the various life cycle stages.

Teaching Philosophy Statements

Science.gov (United States)

Faryadi, Qais

2015-01-01

This article examines the rationale for my teaching philosophy. Using a personal perspective, I explain my objectives, mission, and vision in writing my philosophy of teaching statements. This article also creates a road map and reference points for educators who want to write their own teaching philosophy statements to help them make informed…

Philosophy for Democracy

Science.gov (United States)

Bartels, Rob; Onstenk, Jeroen; Veugelers, Wiel

2016-01-01

Philosophy for Democracy is a research project that aims to examine whether and how Philosophy with Children contributes to the development of democratic skills and attitudes. In the Netherlands, as in almost all Western countries, Philosophy with Children is linked with the movement for citizenship education. This article reports the research on…

RITA (Reactivating p53 and Inducing Tumor Apoptosis) is efficient against TP53abnormal myeloma cells independently of the p53 pathway.

Science.gov (United States)

Surget, Sylvanie; Descamps, Géraldine; Brosseau, Carole; Normant, Vincent; Maïga, Sophie; Gomez-Bougie, Patricia; Gouy-Colin, Nadège; Godon, Catherine; Béné, Marie C; Moreau, Philippe; Le Gouill, Steven; Amiot, Martine; Pellat-Deceunynck, Catherine

2014-06-14

The aim of this study was to evaluate the efficacy of the p53-reactivating drugs RITA and nutlin3a in killing myeloma cells. A large cohort of myeloma cell lines (n = 32) and primary cells (n = 21) was used for this study. This cohort contained cell lines with various TP53 statuses and primary cells with various incidences of deletion of chromosome 17. Apoptosis was evaluated using flow cytometry with Apo2.7 staining of the cell lines or via the loss of the myeloma-specific marker CD138 in primary cells. Apoptosis was further confirmed by the appearance of a subG1 peak and the activation of caspases 3 and 9. Activation of the p53 pathway was monitored using immunoblotting via the expression of the p53 target genes p21, Noxa, Bax and DR5. The involvement of p53 was further studied in 4 different p53-silenced cell lines. Both drugs induced the apoptosis of myeloma cells. The apoptosis that was induced by RITA was not related to the TP53 status of the cell lines or the del17p status of the primary samples (p = 0.52 and p = 0.80, respectively), and RITA did not commonly increase the expression level of p53 or p53 targets (Noxa, p21, Bax or DR5) in sensitive cells. Moreover, silencing of p53 in two TP53(mutated) cell lines failed to inhibit apoptosis that was induced by RITA, which confirmed that RITA-induced apoptosis in myeloma cells was p53 independent. In contrast, apoptosis induced by nutlin3a was directly linked to the TP53 status of the cell lines and primary samples (p RITA, in contrast to nutlin3a, effectively induced apoptosis in a subset of MM cells independently of p53. The findings and could be of interest for patients with a 17p deletion, who are resistant to current therapies.

REMOTE SENSING DAMAGE ASSESSMENT OF CHEMICAL PLANTS AND REFINERIES FOLLOWING HURRICANES KATRINA AND RITA

Science.gov (United States)

The massive destruction brought by Hurricanes Katrina and Rita also impacted the many chemical plants and refineries in the region. The achievement of this rapid analysis capability highlights the advancement of this technology for air quality assessment and monitoring. Case st...

Rita Thalmann (1926-2013), Pioneer of Women’s History

OpenAIRE

Hoock-Demarle, Marie-Claire

2017-01-01

Born in Nuremberg to a German-Jewish father and a Swiss-Jewish mother, Rita Thalmann fled the Nazi regime with her family in 1933, first taking refuge in Switzerland and then in France. After losing both her father (denounced and deported to Auschwitz), and her mother (who died of malnutrition while interned in Dijon), she survived the war through a support network organized by the headmistress of Dijon’s girls’ lycée, Marcelle Pardé, a member of the Resistance later deported to Ravensbrück. ...

Philosophy, policies, and procedures - The three P's of flight-deck operations

Science.gov (United States)

Degani, Asaf; Wiener, Earl L.

1991-01-01

Standard operating procedures are drafted and provided to flightcrews to dictate the manner in which tasks are carried out. Failure to conform to Standard Operating Procedures (SOP) is frequently listed as the cause of violations, incidents, and accidents. However, procedures are often designed piecemeal, rather than being based on a sound philosophy of operations and policies that follow from such a philosophy. A framework of philosophy, policies, and procedures is proposed.

Masses of Formal Philosophy

DEFF Research Database (Denmark)

Masses of Formal Philosophy is an outgrowth of Formal Philosophy. That book gathered the responses of some of the most prominent formal philosophers to five relatively open and broad questions initiating a discussion of metaphilosophical themes and problems surrounding the use of formal methods i...... in philosophy. Including contributions from a wide range of philosophers, Masses of Formal Philosophy contains important new responses to the original five questions.......Masses of Formal Philosophy is an outgrowth of Formal Philosophy. That book gathered the responses of some of the most prominent formal philosophers to five relatively open and broad questions initiating a discussion of metaphilosophical themes and problems surrounding the use of formal methods...

Philosophical Questions about Teaching Philosophy: What's at Stake in High School Philosophy Education?

Science.gov (United States)

Norris, Trevor

2015-01-01

What is at stake in high school philosophy education, and why? Why is it a good idea to teach philosophy at this level? This essay seeks to address some issues that arose in revising the Ontario grade 12 philosophy curriculum documents, significant insights from philosophy teacher education, and some early results of recent research funded by the…

Experimental philosophy.

Science.gov (United States)

Knobe, Joshua; Buckwalter, Wesley; Nichols, Shaun; Robbins, Philip; Sarkissian, Hagop; Sommers, Tamler

2012-01-01

Experimental philosophy is a new interdisciplinary field that uses methods normally associated with psychology to investigate questions normally associated with philosophy. The present review focuses on research in experimental philosophy on four central questions. First, why is it that people's moral judgments appear to influence their intuitions about seemingly nonmoral questions? Second, do people think that moral questions have objective answers, or do they see morality as fundamentally relative? Third, do people believe in free will, and do they see free will as compatible with determinism? Fourth, how do people determine whether an entity is conscious?

Jazz-Philosophy Fusion

Directory of Open Access Journals (Sweden)

James Tartaglia

2016-07-01

Full Text Available In this paper I describe and provide a justification for the fusion of jazz music and philosophy which I have developed; the justification is provided from the perspectives of both jazz and philosophy. I discuss two of my compositions, based on philosophical ideas presented by Schopenhauer and Derek Parfit respectively; links to sound files are provided. The justification emerging from this discussion is that philosophy produces ‘non-argumentative effects’ which provide suitable material for artistic expression and exploration. These effects – which are often emotional – are under-recognised in philosophy, but they do important philosophical work in demarcating the kinds of truths we want to discover, and in sustaining our search for them. Jazz-Philosophy Fusion can help to increase metaphilosophical self-consciousness about these effects, while also helping to counteract any undue persuasive force they may achieve. Jazz is a particularly suitable medium because it has independently developed a concern with philosophical ideas; because of strong parallels between jazz and philosophy which explain their mutual openness to fusions, and because improvisation very effectively facilitates the direct audience engagement essential to inducing these effects.

Sediment deposition from Hurricane Rita on Hackberry Beach chenier in southwestern Louisiana: Chapter 6E in Science and the storms-the USGS response to the hurricanes of 2005

Science.gov (United States)

Faulkner, Stephen; Barrow, Wylie; Doyle, Thomas; Baldwin, Michael; Michot, Thomas; Wells, Christopher; Jeske, Clint

2007-01-01

Hurricane Rita significantly impacted the chenier forests of southwestern Louisiana, an important habitat for Neotropical migratory birds. Sediment deposition was measured along transects at Hackberry Beach chenier, and Rita's effects on chenier structure and morphology were determined.

Philosophy as Estrangement

DEFF Research Database (Denmark)

Raffnsøe, Sverre

interested in philosophy as a privileged object of investigation and investment ‐ an aim in itself. There are, however, moments and situations in my life where an interest in philosophy has appeared or is necessarily forced upon me; these are times when philosophy appears as a seemingly unavoidable...... and essential questioning of fundamentals,– as a ‘basic’ need. This being said, it can be annoying as well as cumbersome. Philosophy as a ‘basic’ need makes itself felt as an estrangement that has always already taken place. It takes the form of a “Schritt zurück” in which one pulls away from, problematizes...

Dual targeting of wild-type and mutant p53 by small molecule RITA results in the inhibition of N-Myc and key survival oncogenes and kills neuroblastoma cells in vivo and in vitro.

Science.gov (United States)

Burmakin, Mikhail; Shi, Yao; Hedström, Elisabeth; Kogner, Per; Selivanova, Galina

2013-09-15

Restoration of the p53 function in tumors is a promising therapeutic strategy due to the high potential of p53 as tumor suppressor and the fact that established tumors depend on p53 inactivation for their survival. Here, we addressed the question whether small molecule RITA can reactivate p53 in neuroblastoma and suppress the growth of neuroblastoma cells in vitro and in vivo. The ability of RITA to inhibit growth and to induce apoptosis was shown in seven neuroblastoma cell lines. Mechanistic studies were carried out to determine the p53 dependence and the molecular mechanism of RITA-induced apoptosis in neuroblastoma, using cell viability assays, RNAi silencing, co-immunoprecipitation, qPCR, and Western blotting analysis. In vivo experiments were conducted to study the effect of RITA on human neuroblastoma xenografts in mice. RITA induced p53-dependent apoptosis in a set of seven neuroblastoma cell lines, carrying wild-type or mutant p53; it activated p53 and triggered the expression of proapoptotic p53 target genes. Importantly, p53 activated by RITA inhibited several key oncogenes that are high-priority targets for pharmacologic anticancer strategies in neuroblastoma, including N-Myc, Aurora kinase, Mcl-1, Bcl-2, Wip-1, MDM2, and MDMX. Moreover, RITA had a strong antitumor effect in vivo. Reactivation of wild-type and mutant p53 resulting in the induction of proapoptotic factors along with ablation of key oncogenes by compounds such as RITA may be a highly effective strategy to treat neuroblastoma. ©2013 AACR.

Caring to Care: Applying Noddings' Philosophy to Medical Education.

Science.gov (United States)

Balmer, Dorene F; Hirsh, David A; Monie, Daphne; Weil, Henry; Richards, Boyd F

2016-12-01

The authors argue that Nel Noddings' philosophy, "an ethic of caring," may illuminate how students learn to be caring physicians from their experience of being in a caring, reciprocal relationship with teaching faculty. In her philosophy, Noddings acknowledges two important contextual continuities: duration and space, which the authors speculate exist within longitudinal integrated clerkships. In this Perspective, the authors highlight core features of Noddings' philosophy and explore its applicability to medical education. They apply Noddings' philosophy to a subset of data from a previously published longitudinal case study to explore its "goodness of fit" with the experience of eight students in the 2012 cohort of the Columbia-Bassett longitudinal integrated clerkship. In line with Noddings' philosophy, the authors' supplementary analysis suggests that students (1) recognized caring when they talked about "being known" by teaching faculty who "cared for" and "trusted" them; (2) responded to caring by demonstrating enthusiasm, action, and responsibility toward patients; and (3) acknowledged that duration and space facilitated caring relations with teaching faculty. The authors discuss how Noddings' philosophy provides a useful conceptual framework to apply to medical education design and to future research on caring-oriented clinical training, such as longitudinal integrated clerkships.

A new perspective on autism: Rita Leal School

Directory of Open Access Journals (Sweden)

Rodrigues T. F.

2016-12-01

Full Text Available Guided by the principle that scientific knowledge should serve to transform reality and create suitable conditions of life for all, the Portuguese Association for Relational-Historical Psychology (APPRH founded a school named RITA LEAL (RLS, with a therapeutic purpose based on new perspectives for treating autism — perspectives quite different from instrumental and behavioral learning programs. The Rita Leal School (Leal, 1975/2004, 1997, 2005, 2010 is rooted in the theory that mental development is based on a mutually contingent emotional relationship, while it underwrites Vygotsky’s concept of the Zone of Proximal Development (ZPD and Mediation (1930/2004, 1934/2009. Learning to read is a complex process which individuals with Autism Spectrum Disorder (ASD master slowly and with difficulty. We analyzed the process of learning to read of two ASD children accompanied by peers without special educational needs, aiming to pinpoint distinct aspects of their progress. We used the Observer Software Program to collect and analyze observations of their performance, which were understood as data to be classified according to previously specified codes. We believed we could demonstrate that, especially in the case of ASD children, learning is dependent on contingent responses and adequate levels of mediation. The technical team at the RLS has continuous clinical supervision. That is because we believe this supervision is what permits the team to undergo a process of de-centering, becoming more empathic and accessible to the autists. This makes the team’s intervention more efficient, because it becomes more aware of each autist’s individual characteristics, and therefore more available to respond to the autist’s needs.

An Axisymmetric View of Concentric Eyewall Evolution in Hurricane Rita (2005)

Science.gov (United States)

2012-08-01

of Hurricane Hugo (1989). Mon. Wea. Rev., 136, 1237–1259. Martinez, Y., G. Brunet, and M. K. Yau, 2010: On the dynamics of two-dimensional hurricane ...An Axisymmetric View of Concentric Eyewall Evolution in Hurricane Rita (2005) MICHAEL M. BELL Naval Postgraduate School, Monterey, California, and... Hurricane Research Division, Miami, Florida WEN-CHAU LEE National Center for Atmospheric Research,* Boulder, Colorado (Manuscript received 23 June 2011, in

Lessons learned from the deadly sisters: drug and alcohol treatment disruption, and consequences from Hurricanes Katrina and Rita.

Science.gov (United States)

Maxwell, Jane Carlisle; Podus, Deborah; Walsh, David

2009-01-01

This paper reports on the effects of Hurricanes Katrina and Rita on drug and alcohol treatment in Texas in 2005-2006. Findings are based on a secondary analysis of administrative data on 567 hurricane-related admissions and on interview data from a sample of 20 staff in 11 treatment programs. Katrina evacuees differed from Rita clients in terms of demographics and primary problem substances and treatment needs, while the experiences of program staff and needed changes to improve disaster readiness were more similar. Additional systematic research is needed to document the intermediate and long-term impacts of the storms in these and other affected areas.

Sweet resin bush on the Santa Rita Experimental Range: An eradication effort

Science.gov (United States)

Larry D. Howery; Bruce D. Munda; Dan G. Robinett; Harry H. Buck

2003-01-01

Sweet resin bush (Euryops subcarnosus DC ssp. vulgaris B. Nord; or, Euryops multifidis (L. f.) DC.), a South African shrub introduced to Arizona in the 1930s, was discovered on the Santa Rita Experimental Range (SRER) in 1998. Due to the threat of spread of this invasive plant and its potential to cause adverse environmental and economic effects, and because it posed a...

Fundamental philosophy on the safety design of the HTTR-IS hydrogen production system

International Nuclear Information System (INIS)

Ohashi, Kazutaka; Nishihara, Tetsuo; Kunitomi, Kazuhiko

2007-01-01

Japan Atomic Energy Agency (JAEA) has been conducting an R and D work on the VHTR reactor system and IS hydrogen production system to realize hydrogen production using nuclear heat. As a part of this activity, JAEA is planning to connect an IS test system to the High Temperature Engineering Test Reactor (HTTR) to demonstrate its technical feasibility. This paper proposes a fundamental philosophy on the safety design of the HTTR-IS hydrogen production system including the methodology to select postulated abnormal events and its event sequences and to define safety functions of the IS system to ensure the reactor safety. Also the measure to clarify the IS system as non-reactor system is proposed. (author)

Inelastic neutron scattering experiments with the monochromatic imaging mode of the RITA-II spectrometer

DEFF Research Database (Denmark)

Bahl, Christian Robert Haffenden; Lefmann, Kim; Abrahamsen, Asger Bech

2006-01-01

Recently a monochromatic multiple data taking mode has been demonstrated for diffraction experiments using a RITA type cold neutron spectrometer with a multi-bladed analyser and a position-sensitive detector. Here, we show how this mode can be used in combination with a flexible radial collimator...

French PWR Safety Philosophy

International Nuclear Information System (INIS)

Conte, M. M.

1986-01-01

The first 900 MWe units, built under the American Westinghouse licence and with reference to the U. S. regulation, were followed by 28 standardized units, C P1 and C P2 series. Increasing knowledge and lessons learned from starting and operating experience of French nuclear power plants, completed by the experience learned from the operation of foreign reactors, has contributed to the improvement of French PWR design and safety philosophy. As early as 1976, this experience was taken into account by French Safety organisms to discuss, with Electricite de France, the safety options for the planned 1300 MWe units, P4 and P4 series. In 1983, the new reactor scheduled, Ni4 series 1400 MWe, is a totally French design which satisfies the French regulations and other French standards and codes. Based on a deterministic approach, the French safety analysis was progressively completed by a probabilistic approach each of them having possibilities and limits. Increasing knowledge and lessons learned from operating experience have contributed to the French safety philosophy improvement. The methodology now applied to safety evaluation develops a new facet of the in depth defense concept by taking highly unlikely events into consideration, by developing the search of safety consistency of the design, and by completing the deterministic approach by the probabilistic one

Design philosophy for the new harwell α,β/γ ILW facility and associated NDA instrumentation with regard to criticality safety

International Nuclear Information System (INIS)

Chard, P.M.J.; Cooper, T.J.; Croft, S.; Lambert, K.P.; Syme, D.B.; Wilkins, C.G.

1995-01-01

A new Alpha Beta/Gamma Waste Facility is currently being commissioned at Harwell. The facility provides for the assay and re-packing of existing Intermediate Level Waste (ILW) cans and future ILW arisings into 400 litre drums which are then stored in an integral vault prior to ultimate disposal. Paramount to the design philosophy for the plant was the safe retrieval and movement of radioactive material throughout the treatment process and the avoidance of criticality and other hazards. This required sound managerial controls underpinned by state-of-the-art non destructive assay (NDA) measurements. These consist primarily of a gamma spectrometer and a passive/active neutron interrogator. Their prime role is to confirm can identity against plant records and enable a fissile inventory to be developed for each can for criticality assessment. An expert system aids interpretation of assay results and the reconciliation of discrepancies. This paper describes the design philosophy with emphasis on the control measures used and the operation of the expert system. (author)

Philosophy of the social sciences

Directory of Open Access Journals (Sweden)

J. A. Kimelyev

2014-01-01

Full Text Available Philosophy of social science is a branch of philosophy where relations between philosophy and social sciences are traced and investigated. The main functions of philosophy of social science are: to work out social ontology, methodology and metatheory of social science.

How student teachers understand African philosophy

Directory of Open Access Journals (Sweden)

Matsephe M. Letseka

2012-10-01

Full Text Available The question ‘What constitutes African philosophy?’ was first raised with the publication of Placide Tempels’s seminal work Bantu philosophy in 1959. Tempels’s book inevitably elicited considerable critical response from African philosophers, which culminated in a wide range of publications such as Wiredu’s (1980 Philosophy and an African culture, Hountondji’s (1983 African philosophy: Myth and reality, Oruka’s (1990 Sage philosophy: Indigenous thinkers and modern debate on African philosophy, Shutte’s (1993 Philosophy for Africa, Masolo’s (1994 African philosophy in search of identity and Gyekye’s (1995 An essay of African philosophical thought: The Akan conceptual scheme. It has been over 60 years since the publication of Temples’s book and there continues to be serious debate about African philosophy. This article sought to contribute to the debate on the various conceptions of African philosophy, but with a focus on the challenges of teaching African philosophy to Philosophy of Education students at an open distance learning institution in South Africa. This article discussed the tendency amongst undergraduate Philosophy of Education students to conflate and reduce African philosophy to African cultures and traditions, and to the notion of ubuntu, and sought to understand the reasons for students’ inclination to treat African philosophy in this way. It examined students’ background knowledge of African philosophy, their critical thinking skills and whether their official study materials are selected and packaged in a manner that, in fact, adds to the challenges they face. Finally, the article explored the ways in which Philosophy of Education lecturers can adapt their pedagogy to provide students with a better understanding of African philosophy.

Meie seast on lahkunud saksa keele tõlk Rita Tasa : [3.12.1930-16.07.2007

Index Scriptorium Estoniae

2007-01-01

Järelhüüe kirjandusteadlasele, Tartu Ülikooli saksa kirjanduse õppejõule, Tallinna Pedagoogilise Instituudi saksa ja maailmakirjanduse õppejõule, saksa keele kadeedri juhatajale, saksa, šveitsi ning austria kirjanduse tõlkijale Rita Tasale

Physics Needs Philosophy. Philosophy Needs Physics

Science.gov (United States)

Rovelli, Carlo

2018-05-01

Contrary to claims about the irrelevance of philosophy for science, I argue that philosophy has had, and still has, far more influence on physics than is commonly assumed. I maintain that the current anti-philosophical ideology has had damaging effects on the fertility of science. I also suggest that recent important empirical results, such as the detection of the Higgs particle and gravitational waves, and the failure to detect supersymmetry where many expected to find it, question the validity of certain philosophical assumptions common among theoretical physicists, inviting us to engage in a clearer philosophical reflection on scientific method.

Philosophy of phenomenology: how understanding aids research.

Science.gov (United States)

Converse, Mary

2012-01-01

To assist the researcher in understanding the similarities and differences between the Husserlian and Heideggerian philosophies of phenomenology, and how that philosophy can inform nursing research as a useful methodology. Nurse researchers using phenomenology as a methodology need to understand the philosophy of phenomenology to produce a research design that is philosophically congruent. However, phenomenology has a long and complex history of development, and may be difficult to understand and apply. The author draws from Heidegger (1962), Gadamer (2004), and nurse scholars and methodologists. To give the reader a sense of the development of the philosophy of phenomenology, the author briefly recounts its historical origins and interpretations, specifically related to Husserl, Heidegger and Gadamer. The author outlines the ontological and epistemological assumptions of Husserlian and Heideggerian phenomenology and guidance for methodology inspired by these philosophers. Difficulties with engaging in phenomenological research are addressed, especially the processes of phenomenological reduction and bracketing, and the lack of clarity about the methods of interpretation. Despite its complexity, phenomenology can provide the nurse researcher with indepth insight into nursing practice. An understanding of phenomenology can guide nurse researchers to produce results that have meaning in nursing patient care.

Rita Felski, The Limits of Critique

Directory of Open Access Journals (Sweden)

Corrado Confalonieri

2017-05-01

Full Text Available Professore di Letteratura inglese presso la University of Virginia – e dal 2016 Niels Bohr Professor alla University of Southern Denmark per un progetto quinquennale dedicato agli usi sociali della letteratura –, Rita Felski non è, all’interno del gruppo di studiosi che lavorano negli Stati Uniti, tra quelli più noti al pubblico italiano, e ciò non soltanto perché mancano traduzioni dei suoi libri, ma per il fatto che diversi tra questi sono rivolti a un contesto piuttosto specificamente americano. Non fa eccezione The Limits of Critique, il libro che qui si presenta e che dovrebbe costituire la seconda uscita di una trilogia avviata nel 2008 con Uses of Literature (Wiley-Blackwell e destinata a concludersi con un volume ora in fase di elaborazione dedicato al coinvolgimento estetico e alle ragioni per cui, come lettori o spettatori, siamo affascinati da un’opera d’arte.

Safety design philosophy of the ABWR for the next generation LWRs

International Nuclear Information System (INIS)

Sato, Takashi; Akinaga, Makoto; Kojima, Yoshihiro

2009-01-01

The paper presents safety design philosophy of the advanced boiling water reactor (ABWR) to be reflected in developing the next generation light water reactors (LWRs). The basic policy of the ABWR safety design was to improve safety and reduce cost simultaneously by reflecting lessons learned of precursors, incidents and accidents that were beyond the design basis such as the Three Mile Island Unit 2 (TMI 2) accident. The ABWR is a fully active safety plant. The ABWR enhanced redundancy and diversity of active safety systems using probabilistic safety assessment (PSA) insights. It adopted a complete three division active emergency core cooling system (ECCS) and attained a very low core damage frequency (CDF) value of less than 10 -7 /ry for internal events. Only very small residual risks, if any, rather exist in external events such as an extremely large earthquake beyond the design basis. This is because external events can constitute a common cause that disables all the redundant active safety systems. Therefore, it is useless to add one more ECCS train and make a four division active ECCS for external events. Nowadays, however, fully passive safety LWRs are already established. Incorporating some of these passive safety systems we can also establish the next generation LWRs that are truly strong against external events. We can establish a plant that can survive a giant earthquake at least three days without AC power source, SA proof safety design that enables no containment failure and no evacuation to eliminate the residual risks. The same basic policy as the ABWR to improve safety and reduce cost simultaneously is again effective for the next generation LWRs. (author)

Philosophy vs the common sense

OpenAIRE

V. V. Chernyshov

2017-01-01

The paper deals with the antinomy of philosophy and the common sense. Philosophy emerges as a way of specifically human knowledge, which purposes analytics of the reality of subjective experience. The study reveals that in order to alienate philosophy from the common sense it was essential to revise the understanding of wisdom. The new, philosophical interpretation of wisdom – offered by Pythagoras – has laid the foundation of any future philosophy. Thus, philosophy emerges, alienating itself...

Empirical philosophy of science

DEFF Research Database (Denmark)

Wagenknecht, Susann; Nersessian, Nancy J.; Andersen, Hanne

2015-01-01

A growing number of philosophers of science make use of qualitative empirical data, a development that may reconfigure the relations between philosophy and sociology of science and that is reminiscent of efforts to integrate history and philosophy of science. Therefore, the first part...... of this introduction to the volume Empirical Philosophy of Science outlines the history of relations between philosophy and sociology of science on the one hand, and philosophy and history of science on the other. The second part of this introduction offers an overview of the papers in the volume, each of which...... is giving its own answer to questions such as: Why does the use of qualitative empirical methods benefit philosophical accounts of science? And how should these methods be used by the philosopher?...

Philosophy, Moral Philosophy, and Counseling Ethics: Not an Abstraction.

Science.gov (United States)

Urofsky, Robert I.; Engels, Dennis W.

2003-01-01

Over the past several decades, increased attention has been given to ethics in the preparation of counselors and psychologists. With that increase comes a number of voices calling for exposure to and integration of not only moral philosophy but other areas of philosophy to enhance understanding and provide a foundation for counseling practice. The…

Hurricane Rita Aerial Photography: High-Resolution Imagery of the Texas and Louisiana Gulf Coast After Landfall

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The imagery posted on this site is of the Texas and Louisiana Gulf Coast after Hurricane Rita made landfall. The regions photographed range from San Luis Pass, Texas...

75 FR 22770 - Gary E. Hall and Rita Hall; Notice of Availability of Environmental Assessment

Science.gov (United States)

2010-04-30

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13652-000-Montana] Gary E. Hall and Rita Hall; Notice of Availability of Environmental Assessment April 22, 2010. In accordance with the National Environmental Policy Act of 1969, as amended, and the Federal Energy Regulatory...

Philosophy of Education Today

Science.gov (United States)

Chambliss, J. J.

2009-01-01

In this review essay J.J. Chambliss assesses the current state of the field of philosophy of education through analysis of four recent edited compilations: Randall Curren's "A Companion to Philosophy of Education"; Nigel Blake, Paul Smeyers, Richard Smith, and Paul Standish's "The Blackwell Guide to Philosophy of Education"; Wilfred Carr's "The…

The provenance and Sm/Nd Model ages of siliciclastic supracrustal rocks of the Faina and Santa Rita Greenstone belts, Goias, Brazil

International Nuclear Information System (INIS)

Resende, Marcelo Goncalves; Jost, Hardy; Lima, Bruno Eustaquio Moreira; Teixeira, Alexandre de Amorim

1999-01-01

The Faina and Santa Rita greenstone belts are two N 60 deg C W trending synclinoria separated by a N 30 deg C E strike-slip fault and rest allochtonous on the adjacent Uva and Caicara granite-gneiss complexes. The belts are made up of lower metakomatiites, followed by metabasalts and thick metasedimentary sequences deposited under contrasting paleogeographic settings. In Faina, the sequence consists of two complete shelf cycles, the first resting on basalts by an erosional unconformity. In Santa Rita, the basalts give gradually place to carbonaceous metashales, unconformably overlain by metarhythmites. Provenance based on trace element geochemistry, mineral chemistry of chloride and muscovite, source-are modeling and REE elements indicate that protoliths of the first shelf cycle of Faina and the carbonaceous metashales of Santa Rita formed under the influence of a source area dominated by mafic ultramafic rocks, whilst during the sedimentation of the second shelf cycle and the metarhythmites of Santa Rita the source-area was dominated by TTG granitoids. Sm-Nd model ages of the lower sedimentary packages vary between 3.0 and 2.8 Ga and the upper between 2.7 and 2.6 Ga. These intervals coincide, respectively, with the estimated age of the underlying, and with the Sm-Nd, Rb-Sr e U-Pb ages of the main granitoids and gneisses of the adjacent complexes. The same data indicate that, during the sedimentation of the first shelf cycle of Faina and the carbonaceous metashales of Santa Rita, both basins had independent source-areas, but shared the same source during the upper sections. Weathering nature and intensity of the source-area calculated by means of geochemical a data suggest that the dramatic change of provenance from the lower to the upper sections is due to the shift from tectonically stable to unstable regimes, interpreted as resulting from the emergence of the island arc whose roots are represented by the adjacent granite-gneiss complexes. (author)

Inability of p53-reactivating compounds Nutlin-3 and RITA to overcome p53 resistance in tumor cells deficient in p53Ser46 phosphorylation.

Science.gov (United States)

Ma, Teng; Yamada, Shumpei; Ichwan, Solachuddin J A; Iseki, Sachiko; Ohtani, Kiyoshi; Otsu, Megumi; Ikeda, Masa-Aki

2012-01-20

The p53 tumor suppressor protein plays key roles in protecting cells from tumorigenesis. Phosphorylation of p53 at Ser46 (p53Ser46) is considered to be a crucial modification regulating p53-mediated apoptosis. Because the activity of p53 is impaired in most human cancers, restoration of wild-type p53 (wt-p53) function by its gene transfer or by p53-reactivating small molecules has been extensively investigated. The p53-reactivating compounds Nutlin-3 and RITA activate p53 in the absence of genotoxic stress by antagonizing the action of its negative regulator Mdm2. Although controversial, Nutlin-3 was shown to induce p53-mediated apoptosis in a manner independent of p53 phosphorylation. Recently, RITA was shown to induce apoptosis by promoting p53Ser46 phosphorylation. Here we examined whether Nutlin-3 or RITA can overcome resistance to p53-mediated apoptosis in p53-resistant tumor cell lines lacking the ability to phosphorylate p53Ser46. We show that Nutlin-3 did not rescue the apoptotic defect of a Ser46 phosphorylation-defective p53 mutant in p53-sensitive tumor cells, and that RITA neither restored p53Ser46 phosphorylation nor induced apoptosis in p53Ser46 phosphorylation-deficient cells retaining wt-p53. Furthermore, treatment with Nutlin-3 or RITA together with adenoviral p53 gene transfer also failed to induce apoptosis in p53Ser46 phosphorylation-deficient cells either expressing or lacking wt-p53. These results indicate that neither Nutlin-3 nor RITA in able to induce p53-mediated apoptosis in the absence of p53Ser46 phosphorylation. Thus, the dysregulation of this phosphorylation in tumor cells may be a critical factor that limits the efficacy of these p53-based cancer therapies. Copyright © 2011 Elsevier Inc. All rights reserved.

Postmodernism: Philosophy of Education

Directory of Open Access Journals (Sweden)

Oleg Bazaluk

2015-07-01

Full Text Available The subject of the research is the philosophy of education and its reflection on the educational process. Based on the analysis of predecessors’ works the author presented the new structure of the philosophy of education which enriches the understanding of its subject, targets and methods of research. The author presented the philosophy of education as a pyramid, the base of which are generalizing the situation of man as a subject andobject of research accumulated in the philosophical anthropology. The first level of the pyramid takes psychology as a science which studies the origin, development and functioning of the psyche. Pedagogy crowns the “pyramid”. The author used the dialectical, system-structural, structural-functional method, as well as methods of comparison, analysis and synthesis. The main conclusion of the study is to prove that the philosophy of education in their new understanding is not only a theoretical understanding of basics and demonstrations of the educational process, but also a practice, the direct embodiment of the theoretical developments in the education in the everyday life. Using historical and philosophical analysis, the author shows that the philosophy of education does not just depend on the state of social philosophy (and philosophy in general, but also through its methodological apparatus it realizes the established philosophical (ideological paradigm in the different pedagogical practices.

Vascular plants and a brief history of the Kiowa and Rita Blanca National Grasslands

Science.gov (United States)

Donald L. Hazlett; Michael H. Schiebout; Paulette L. Ford

2009-01-01

Administered by the USDA Forest Service, the Kiowa and Rita Blanca National Grasslands occupy 230,000 acres of public land extending from northeastern New Mexico into the panhandles of Oklahoma and Texas. A mosaic of topographic features including canyons, plateaus, rolling grasslands and outcrops supports a diverse flora. Eight hundred twenty six (826) species of...

Environmental Impact Report from Santa Rita Hydroelectric Power Plant (Minas Gerais State - Brazil): technical strategic for its elaboration; Relatorio de Impacto Ambiental da Usina Hidreletrica da Santa Rita (MG): estrategica tecnica para sua elaboracao

Energy Technology Data Exchange (ETDEWEB)

Souza, J.A. de; Marques Neto, F P [Companhia Energetica de Minas Gerais (CEMIG), Belo Horizonte, MG (Brazil)

1990-12-31

The steps for developing the technical strategies used on the elaboration of Environmental Impact Report from Santa Rita Hydroelectric Power Plant, Minas Gerais State, are described, including the influence area, technical requirements, impact identification, technical selection of mitigative measures, impact meaning and strategy for evaluating the identified impacts. (C.G.C.).

saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription.

Science.gov (United States)

Portnoy, Victoria; Lin, Szu Hua Sharon; Li, Kathy H; Burlingame, Alma; Hu, Zheng-Hui; Li, Hao; Li, Long-Cheng

2016-03-01

Small activating RNAs (saRNAs) targeting specific promoter regions are able to stimulate gene expression at the transcriptional level, a phenomenon known as RNA activation (RNAa). It is known that RNAa depends on Ago2 and is associated with epigenetic changes at the target promoters. However, the precise molecular mechanism of RNAa remains elusive. Using human CDKN1A (p21) as a model gene, we characterized the molecular nature of RNAa. We show that saRNAs guide Ago2 to and associate with target promoters. saRNA-loaded Ago2 facilitates the assembly of an RNA-induced transcriptional activation (RITA) complex, which, in addition to saRNA-Ago2 complex, includes RHA and CTR9, the latter being a component of the PAF1 complex. RITA interacts with RNA polymerase II to stimulate transcription initiation and productive elongation, accompanied by monoubiquitination of histone 2B. Our results establish the existence of a cellular RNA-guided genome-targeting and transcriptional activation mechanism and provide important new mechanistic insights into the RNAa process.

"Making Lemonade from Lemons:" Early Childhood Teacher Educators' Programmatic Responses to Hurricanes Katrina and Rita

Science.gov (United States)

DiCarlo, Cynthia F.; Burts, Diane C.; Buchanan, Teresa K.; Aghayan, Carol; Benedict, Joan

2007-01-01

This article describes how early childhood teacher education faculty at one university responded in the aftermath of hurricanes Katrina and Rita and used the disaster to enhance their undergraduate and graduate programs. They explain how they modeled developmentally appropriate practices while responding to community needs. Four companion articles…

PHILOSOPHY IN CONTEMPORARY TIME: RELEVANCE VS ...

African Journals Online (AJOL)

JONATHAN

This proper training of the human mind with the tool of philosophy translates ... students of philosophy do not understand what philosophy students do in their philosophy classes. ..... communication as well as the analysis and synthesis thereof.

Air-cleaning philosophy in a nuclear-materials fabrication plant

International Nuclear Information System (INIS)

Ward, F.Y.; Yoder, R.E.

1982-01-01

At the Department of Energy's Rocky Flats Plant there is a major ventilation improvement project underway. To achieve the desired goals of ALARA regarding radioactivity and toxic material releases and natural phenomena insults, a comprehensive air-cleaning philosophy and policy statement was developed. Design of the upgraded systems were evaluated against these statements and we believe that upon completion of the projects that an efficient system will be demonstrated. the design permits reuse and heat recovery of ventilation air, the optimization of sampling points to reduce analytical laboratory services. This paper discusses the basis of the philosophy and the engineering features incorporated to meet this stated objective. Points of compromise are noted

Archive and laboratory embedded in the landscape: Future of the Santa Rita Experimental Range

Science.gov (United States)

Thomas E. Sheridan

2003-01-01

The Santa Rita Experimental Range (SRER) is both an archive of past ecological research and a laboratory for continuing research embedded in the southern Arizona landscape. The scientific questions being asked there have changed over the last 100 years, but SRER with its monitoring stations and its legacy of repeat photography still offers a unique opportunity to study...

Rangeland livestock production: Developing the concept of sustainability on the Santa Rita Experimental Range

Science.gov (United States)

George B. Ruyle

2003-01-01

The Santa Rita Experimental Range (SRER) was established in 1903 at the behest of concerned stockmen and researchers as the first facility in the United States set aside to study range livestock production. At the time, severe overgrazing of the public domain had seriously reduced carrying capacities of Southwestern rangelands. Researchers on the SRER developed and...

Katrina and Rita were lit up with lightning

Science.gov (United States)

Shao, X.-M.; Harlin, J.; Stock, M.; Stanley, M.; Regan, A.; Wiens, K.; Hamlin, T.; Pongratz, M.; Suszcynsky, D.; Light, T.

Hurricanes generally produce very little lightning activity compared to other noncyclonic storms, and lightning is especially sparse in the eye wall and inner regions within tens of kilometers surrounding the eye [Molinari et al., 1994, 1999]. (The eye wall is the wall of clouds that encircles the eye of the hurricane.) Lightning can sometimes be detected in the outer, spiral rainbands, but the lightning occurrence rate varies significantly from hurricane to hurricane as well as within an individual hurricane's lifetime.Hurricanes Katrina and Rita hit the U.S. Gulf coasts of Louisiana, Mississippi, and Texas, and their distinctions were not just limited to their tremendous intensity and damage caused. They also differed from typical hurricanes in their lightning production rate.

The effect of proximity to hurricanes Katrina and Rita on subsequent hurricane outlook and optimistic bias.

Science.gov (United States)

Trumbo, Craig; Lueck, Michelle; Marlatt, Holly; Peek, Lori

2011-12-01

This study evaluated how individuals living on the Gulf Coast perceived hurricane risk after Hurricanes Katrina and Rita. It was hypothesized that hurricane outlook and optimistic bias for hurricane risk would be associated positively with distance from the Katrina-Rita landfall (more optimism at greater distance), controlling for historically based hurricane risk and county population density, demographics, individual hurricane experience, and dispositional optimism. Data were collected in January 2006 through a mail survey sent to 1,375 households in 41 counties on the coast (n = 824, 60% response). The analysis used hierarchal regression to test hypotheses. Hurricane history and population density had no effect on outlook; individuals who were male, older, and with higher household incomes were associated with lower risk perception; individual hurricane experience and personal impacts from Katrina and Rita predicted greater risk perception; greater dispositional optimism predicted more optimistic outlook; distance had a small effect but predicted less optimistic outlook at greater distance (model R(2) = 0.21). The model for optimistic bias had fewer effects: age and community tenure were significant; dispositional optimism had a positive effect on optimistic bias; distance variables were not significant (model R(2) = 0.05). The study shows that an existing measure of hurricane outlook has utility, hurricane outlook appears to be a unique concept from hurricane optimistic bias, and proximity has at most small effects. Future extension of this research will include improved conceptualization and measurement of hurricane risk perception and will bring to focus several concepts involving risk communication. © 2011 Society for Risk Analysis.

Safety philosophy of gas turbine high temperature reactor (GTHTR300)

International Nuclear Information System (INIS)

Shoji Katanishi; Kazuhiko Kunitomi; Shusaku Shiozawa

2002-01-01

Japan Atomic Energy Research Institute (JAERI) has undertaken the study of an original design concept of gas turbine high temperature reactor, the GTHTR300. The general concept of this study is development of a greatly simplified design that leads to substantially reduced technical and cost requirements. Newly proposed design features enable the GTHTR300 to be an efficient and economically competitive reactor in 2010's. Also, the GTHTR300 fully takes advantage of its inherent safety characteristics. The safety philosophy of the GTHTR300 is developed based on the HTTR (High Temperature Engineering Test Reactor) of JAERI which is the first HTGR in Japan. Major features of the newly proposed safety philosophy for the GTHTR300 are described in this article. (authors)

Philosophy vs the common sense

Directory of Open Access Journals (Sweden)

V. V. Chernyshov

2017-01-01

Full Text Available The paper deals with the antinomy of philosophy and the common sense. Philosophy emerges as a way of specifically human knowledge, which purposes analytics of the reality of subjective experience. The study reveals that in order to alienate philosophy from the common sense it was essential to revise the understanding of wisdom. The new, philosophical interpretation of wisdom – offered by Pythagoras – has laid the foundation of any future philosophy. Thus, philosophy emerges, alienating itself from the common sense, which refers to the common or collective experience. Moreover, the study examines the role of emotions, conformity and conventionality which they play with respect to the common sense. Next the author focuses on the role of philosophical intuition, guided with principles of rationality, nonconformity and scepticism, which the author professes the foundation stones of any sound philosophy. The common sense, described as deeply routed in the world of human emotions, aims at empathy, as the purpose of philosophy is to provide the rational means of knowledge. Therefore, philosophy uses thinking, keeping the permanent efforts to check and recheck data of its own experience. Thus, the first task of philosophical thinking appears to overcome the suggestion of the common sense, which purposes the social empathy, as philosophical intuition aims at independent thinking, the analytics of subjective experience. The study describes the fundamental principles of the common sense, on the one hand, and those of philosophy, on the other. The author arrives to conclusion that the common sense is unable to exceed the limits of sensual experience. Even there, where it apparently rises to a form of any «spiritual unity», even there it cannot avoid referring to the data of commonly shared sensual experience; though, philosophy, meanwhile, goes beyond sensuality, creating a discourse that would be able to alienate from it, and to make its rational

The future of philosophy.

Science.gov (United States)

Searle, J R

1999-12-29

There is no sharp dividing line between science and philosophy, but philosophical problems tend to have three special features. First, they tend to concern large frameworks rather than specific questions within the framework. Second, they are questions for which there is no generally accepted method of solution. And third they tend to involve conceptual issues. For these reasons a philosophical problem such as the nature of life can become a scientific problem if it is put into a shape where it admits of scientific resolution. Philosophy in the 20th century was characterized by a concern with logic and language, which is markedly different from the concerns of earlier centuries of philosophy. However, it shared with the European philosophical tradition since the 17th century an excessive concern with issues in the theory of knowledge and with scepticism. As the century ends, we can see that scepticism no longer occupies centre stage, and this enables us to have a more constructive approach to philosophical problems than was possible for earlier generations. This situation is somewhat analogous to the shift from the sceptical concerns of Socrates and Plato to the constructive philosophical enterprise of Aristotle. With that in mind, we can discuss the prospects for the following six philosophical areas: (1) the traditional mind-body problem; (ii) the philosophy of mind and cognitive science; (iii) the philosophy of language; (iv) the philosophy of society; (v) ethics and practical reasons; (vi) the philosophy of science. The general theme of these investigations, I believe, is that the appraisal of the true significance of issues in the philosophy of knowledge enables us to have a more constructive account of various other philosophical problems than has typically been possible for the past three centuries.

The future of philosophy.

Science.gov (United States)

Searle, J R

1999-01-01

There is no sharp dividing line between science and philosophy, but philosophical problems tend to have three special features. First, they tend to concern large frameworks rather than specific questions within the framework. Second, they are questions for which there is no generally accepted method of solution. And third they tend to involve conceptual issues. For these reasons a philosophical problem such as the nature of life can become a scientific problem if it is put into a shape where it admits of scientific resolution. Philosophy in the 20th century was characterized by a concern with logic and language, which is markedly different from the concerns of earlier centuries of philosophy. However, it shared with the European philosophical tradition since the 17th century an excessive concern with issues in the theory of knowledge and with scepticism. As the century ends, we can see that scepticism no longer occupies centre stage, and this enables us to have a more constructive approach to philosophical problems than was possible for earlier generations. This situation is somewhat analogous to the shift from the sceptical concerns of Socrates and Plato to the constructive philosophical enterprise of Aristotle. With that in mind, we can discuss the prospects for the following six philosophical areas: (1) the traditional mind-body problem; (ii) the philosophy of mind and cognitive science; (iii) the philosophy of language; (iv) the philosophy of society; (v) ethics and practical reasons; (vi) the philosophy of science. The general theme of these investigations, I believe, is that the appraisal of the true significance of issues in the philosophy of knowledge enables us to have a more constructive account of various other philosophical problems than has typically been possible for the past three centuries. PMID:10670025

[Sustainable process improvement with application of 'lean philosophy'].

Science.gov (United States)

Rouppe van der Voort, Marc B V; van Merode, G G Frits; Veraart, Henricus G N

2013-01-01

Process improvement is increasingly being implemented, particularly with the aid of 'lean philosophy'. This management philosophy aims to improve quality by reducing 'wastage'. Local improvements can produce negative effects elsewhere due to interdependence of processes. An 'integrated system approach' is required to prevent this. Some hospitals claim that this has been successful. Research into process improvement with the application of lean philosophy has reported many positive effects, defined as improved safety, quality and efficiency. Due to methodological shortcomings and lack of rigorous evaluations it is, however, not yet possible to determine the impact of this approach. It is, however, obvious that the investigated applications are fragmentary, with a dominant focus on the instrumental aspect of the philosophy and a lack of integration in a total system, and with insufficient attention to human aspects. Process improvement is required to achieve better and more goal-oriented healthcare. To achieve this, hospitals must develop integrated system approaches that combine methods for process design with continuous improvement of processes and with personnel management. It is crucial that doctors take the initiative to guide and improve processes in an integral manner.

Philosophy and Post-Totalitarian Practices

Directory of Open Access Journals (Sweden)

Serhii Yosypenko

2018-04-01

Full Text Available This writing aims to outline the principles of researches on philosophy in Central and Eastern European countries, preferably USSR, in the latest soviet and post-soviet periods. In author’s opinion, the crucial points for such kind of research are: a to discover a correlation between philosophy and the phenomenon of totalitarianism; b to correlate a soviet philosophy with totalitarian experience. The article considers methodological and axiological problems in research of post-totalitarian practices in general as such as in philosophy. In author’s opinion the main problem in development of the post-soviet philosophy is interiorisation of intellectual, cultural and social practices, which were formed concerning to totalitarian experience. This became a reason of “cynicism” and “nihilism” of post-soviet philosophy. It’s impossible to cast mentioned phenomena off without consideration of totalitarian phenomenon and critical reconsideration of the own totalitarian experience.

[Treatment goals in FACE philosophy].

Science.gov (United States)

Martin, Domingo; Maté, Amaia; Zabalegui, Paula; Valenzuela, Jaime

2017-03-01

The FACE philosophy is characterized by clearly defined treatment goals: facial esthetics, dental esthetics, periodontal health, functional occlusion, neuromuscular mechanism and joint function. The purpose is to establish ideal occlusion with good facial esthetics and an orthopedic stable joint position. The authors present all the concepts of FACE philosophy and illustrate them through one case report. Taking into account all the FACE philosophy concepts increases diagnostic ability and improves the quality and stability of treatment outcomes. The goal of this philosophy is to harmonize the facial profile, tooth alignment, periodontium, functional occlusion, neuromuscular mechanism and joint function. The evaluation and treatment approach to vertical problems are unique to the philosophy. © EDP Sciences, SFODF, 2017.

Frauen in Philosophie und Wissenschaft

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Regina Harzer

2006-03-01

Full Text Available Der von Brigitte Doetsch herausgegebene Band präsentiert die aktuelle Feministische Philosophie und sammelt Beiträge, die Einblick geben in den gegenwärtigen Forschungsstand, wie ihn „Philosophinnen im dritten Jahrtausend“ erreicht haben. Insgesamt neun, zum Teil interdisziplinär ausgerichtete Arbeiten werden vorgestellt. Das Themenspektrum ist weit: Geschichte der Philosophie; Politische Philosophie und Naturphilosophie; Epistemologie; Biopolitik und Bioethik als Bereiche praktischer Philosophie; Forschung über Geschlechterverhältnisse. Alle Beiträge gehen zurück auf eine Vortragsreihe des Braunschweiger Zentrums für Gender Studies (www.genderzentrum.de. Leser/-innen erhalten einen guten Überblick über die aktuelle Frauenforschung aus der Sicht theoretischer und praktischer Philosophie.

Philosophy with Guts

Science.gov (United States)

Sherman, Robert R.

2014-01-01

Western philosophy, from Plato on, has had the tendency to separate feeling and thought, affect and cognition. This article argues that a strong philosophy (metaphorically, with "guts") utilizes both in its work. In fact, a "complete act of thought" also will include action. Feeling motivates thought, which formulates ideas,…

Philosophy and Literature; Philosophy as Literature: Call for Papers

Directory of Open Access Journals (Sweden)

2013-11-01

Full Text Available Plato wrote both stories and argument as a way of investigating philosophical problems. For Plato, the choice of literary form was essential to the quest for philosophical truth. Ever since, philosophical reflection has found expression in numerous literary forms, both creative and conventional. And so, we have Platonic and Humean dialogues, Cartesian meditations, Enlightenment fables, Kierkegaardian narratives, Nietzchean parables and aphorisms, Russellian mathematics, Wittgensteinian tractatuses and investigations, as well as all the standard literary forms of novels, novellas, poems, plays, and songs. Transnational Literature is seeking papers for a special edition of the journal which will be dedicated to the literary expression of philosophy. Rather than readings of philosophy in literature (of mapping particular philosophical frameworks onto works of literature, we invite explorations of philosophy as literature and we invite these explorations to also address the journal’s transnational focus by exploring the crossing of cultural, national and temporal boundaries. The following ideas are of particular interest: •\tPhilosophy and literature as ‘embattled adversaries’ (Calvino and the breaking down of boundaries between philosophy and literature. •\tPhilosophical fiction as an alternative mode of philosophical reflection and investigation and/or experimental method. (George Eliot’s novels, for example, as ‘a set of experiments in life… endeavour[s] to see what our thought and emotion may be capable of.’ •\tThe use of literary devices in philosophical writing to express philosophical facts / metaphysical truths. (Locke’s metaphorical ‘candle within us’ becomes the factual ‘intuition.’ •\tThe use of literary devices in creative fiction to do the work of philosophy. (Exposition as a way of interrupting narrative to keep reader attentive to the task of enquiry. Point-of-view as ethical device. Ellipsis as getting

Positive Traits versus Previous Trauma: Racially Different Correlates with PTSD Symptoms among Hurricane Katrina-Rita Volunteers

Science.gov (United States)

Ai, Amy L.; Plummer, Carol; Kanno, Hanae; Heo, Grace; Appel, Hoa B.; Simon, Cassandra E.; Spigner, Clarence

2011-01-01

This study compared risks and protective factors for acquiring symptoms of posttraumatic stress disorder (PTSD) between African-American (n = 299) and European-American (n = 206) student volunteers 3 months after Hurricanes Katrina and Rita (H-KR). Respondents retrospectively provided information on peritraumatic emotional reactions and previous…

Morphological responses of the Wax Lake Delta, Louisiana, to Hurricanes Rita

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Fei Xing

2017-12-01

Full Text Available This study examines the morphodynamic response of a deltaic system to extreme weather events. The Wax Lake Delta (WLD in Louisiana, USA, is used to illustrate the impact of extreme events (hurricanes on a river-dominated deltaic system. Simulations using the open source Delft3D model reveal that Hurricane Rita, which made landfall 120 km to the west of WLD as a Category 3 storm in 2005, caused erosion on the right side and deposition on the left side of the hurricane eye track on the continental shelf line (water depth 10 m to 50 m. Erosion over a wide area occurred both on the continental shelf line and in coastal areas when the hurricane moved onshore, while deposition occurred along the Gulf coastline (water depth < 5 m when storm surge water moved back offshore. The numerical model estimated that Hurricane Rita’s storm surge reached 2.5 m, with maximum currents of 2.0 m s–1, and wave heights of 1.4 m on the WLD. The northwestern-directed flow and waves induced shear stresses, caused erosion on the eastern banks of the deltaic islands and deposition in channels located west of these islands. In total, Hurricane Rita eroded more than 500,000 m3 of sediments on the WLD area. Including waves in the analysis resulted in doubling the amount of erosion in the study area, comparing to the wave-excluding scenario. The exclusion of fluvial input caused minor changes in deltaic morphology during the event. Vegetation cover was represented as rigid rods in the model which add extra source terms for drag and turbulence to influence the momentum and turbulence equations. Vegetation slowed down the floodwater propagation and decreased flow velocity on the islands, leading to a 47% reduction in the total amount of erosion. Morphodynamic impact of the hurricane track relative to the delta was explored. Simulations indicate that the original track of Hurricane Rita (landfall 120 km west of the WLD produced twice as much erosion and deposition at the delta

Orkaan Rita ähvardab rüüstata USA naftatööstuse südame / Annika Matson

Index Scriptorium Estoniae

Matson, Annika, 1976-

2005-01-01

Orkaan Rita läheneb USA naftatööstuse südamele Texasele, kus toodetakse veerand USA naftatoodetest. Diagramm: Naftafirmade aktsiate tõus. Vt. samas: Bensiini hinna olulist tõusu Eestis prognoosida oleks ennatlik

Constructive philosophy of technology and responsible innovation

NARCIS (Netherlands)

Brey, Philip A.E.; Franssen, M.; Vermaas, P.E.; Kroes, P.; Meijers, A.W.M.

2016-01-01

This essay argues for a new turn after the empirical turn in the philosophy of technology: the societal turn, which is the turn from reflective philosophy of technology (academic philosophy concerned with analysis and understanding) to constructive philosophy of technology (philosophy that is

Mammals of medium and large size in Santa Rita do Sapucaí, Minas Gerais, southeastern Brazil

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Eduardo, A. A.

2009-01-01

Full Text Available The diversity of Brazilian vertebrates is regarded among the highest in the world. However, the biologicaldiversity is still mostly unknown and a good part of it is seriously threatened by human activities. This study aimed toinventory the medium and large size mammals present in the Reserva Biológica de Santa Rita do Sapucaí, an Atlanticforest reserve located in Santa Rita do Sapucaí, southeastern Brazil. Sand-plots, photographic traps and searches foranimal tracks on pre-existent trails in the area, were carried out once every two months between May 2006 andFebruary 2007. The sand-plots and tracks were inspected during five consecutive days per sampling. We obtained 108records of 15 species, mostly of carnivorans. Two confirmed species are threatened with extinction in Brazil (Callithrixaurita and Leopardus pardalis. The results suggest that the sampled reserve has high species richness and plays animportant role in conservation of mammals in this landscape, including species threatened with extinction.

Advances in philosophy and environment in Iberoamerica. Meaningful link between philosophy and environmental sciences

International Nuclear Information System (INIS)

Bugallo, Alicia Irene

2007-01-01

The growing expansion of environmental conscience in the last thirty years of the X X century has influenced the field of philosophy, especially practical philosophy, through the questioning of beliefs, values and goals of industrial civilization. The emergence of the eco philosophy realm was accompanied by the incidence of different scientific disciplines as ecology, biology, economy, anthropology or sociology. But together with these influences, environmental philosophy remains forcefully normative, as a kind of sophia, wisdom. It implies prescriptions, not only scientific description and prediction. The consideration of the term biodiversity as a thick ethical concept shows this integration of descriptive and normative

Why Philosophy Matters

Science.gov (United States)

Mason, Richard

2005-01-01

The motives of philosophers tend to be personal. Philosophy has mattered politically as part of continuing political debates. Its effects on politics, religion and the development of the sciences have been evident. Philosophy has been supposed to have special educational value, from its contents or from the benefits of its methods and arguments.…

Truth in Philosophy

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Tibor R. Machan

2011-03-01

Full Text Available Can there be truth in philosophy? A problem: it is philosophy, its various schools, that advances what counts as true versus false, how to go about making the distinction. This is what I wish to focus on here and see if some coherent, sensible position could be reached on the topic.

Transformative experiences for Hurricanes Katrina and Rita disaster volunteers.

Science.gov (United States)

Clukey, Lory

2010-07-01

The massive destruction caused by Hurricanes Katrina and Rita in 2005 provided an opportunity for many volunteers to be involved with disaster relief work. Exposure to devastation and personal trauma can have long-lasting and sometimes detrimental effects on people providing help. This qualitative study explored the experience of volunteer relief workers who provided disaster relief services after the hurricanes. Three major themes emerged: emotional reactions that included feelings of shock, fatigue, anger and grief as well as sleep disturbances; frustration with leadership; and life-changing personal transformation. Stress reactions were noted but appeared to be mitigated by feelings of compassion for the victims and personal satisfaction in being able to provide assistance. Suggestions are provided for further research.

Missed by the Mass Media: The Houma, Pointe-au-Chien, and Hurricanes Katrina and Rita

Science.gov (United States)

Collins, Robert Keith

2008-01-01

This case study investigates the media discourse from Houma and Pointe-au-Chien tribal leaders in Louisiana on their experiences with Hurricanes Katrina and Rita. One section briefly engages the discourse as discernable from the reports found in Native American and non-Native American news media. Included is a brief yet close examination of these…

The Philosophy of University Housing

Science.gov (United States)

Wallace, James A.

2012-01-01

This article examines a stated philosophy of university housing and the philosophy's effect on the facilitation of the personal and intellectual growth of students residing in the residence halls and the development of a sense of community. This particular philosophy governs the housing operations at Southern Illinois University at Carbondale.…

Philosophy of art and art of philosophy | Etim | Sophia: An African ...

African Journals Online (AJOL)

This paper is an attempt to examine the relationship between philosophy and art. Philosophy and art can be seen primarily as two distinct but logically related phenomena in human experience. For although they differ in subject matter, each of them does have implications for the other in the sphere of knowledge and ...

From the incident command center oil spills from Hurricanes Katrina and Rita

Energy Technology Data Exchange (ETDEWEB)

Guidry, R.J. [Lousiana Oil Spill Coordinator' s Office, Baton Rouge, LA (United States)

2006-07-01

Approximately 30.2 million litres of oil were discharged during Hurricanes Katrina and Rita. A total of 230 incidents were reported to the state's spill response community, including ruptured pipelines, damaged and moved storage tanks, refineries, and sunken vessels. By January 2006, industry had reported the recovery of 14.7 million litres of oil. After Hurricane Rita, a further 234 off- and onshore incidents were reported. This paper presented a chronology from August 26 2005 through to June 2006 of clean-up activities for both hurricanes, with specific reference to logistic and communications issues associated with working in environments that are difficult to access due to damaged transportation infrastructure. An outline of the Louisiana Oil Spill Coordinator's Office's role in the incidents was presented, as well as an overview of the Louisiana State Contingency Plan. It was noted that the lack of communications systems caused considerable difficulties for responders. It was concluded that responses to hurricanes can be made more effective by having all response communities incident command structure (ICS)-trained with a thorough knowledge of the National Response Plan as it relates to the National Contingency Plan. Ensuring that plans are operational, having clear lines of authority on all hurricane-related issues, and having a robust communications plan were recommended, as well as the ability to respond without communications.

From the incident command center oil spills from Hurricanes Katrina and Rita

International Nuclear Information System (INIS)

Guidry, R.J.

2006-01-01

Approximately 30.2 million litres of oil were discharged during Hurricanes Katrina and Rita. A total of 230 incidents were reported to the state's spill response community, including ruptured pipelines, damaged and moved storage tanks, refineries, and sunken vessels. By January 2006, industry had reported the recovery of 14.7 million litres of oil. After Hurricane Rita, a further 234 off- and onshore incidents were reported. This paper presented a chronology from August 26 2005 through to June 2006 of clean-up activities for both hurricanes, with specific reference to logistic and communications issues associated with working in environments that are difficult to access due to damaged transportation infrastructure. An outline of the Louisiana Oil Spill Coordinator's Office's role in the incidents was presented, as well as an overview of the Louisiana State Contingency Plan. It was noted that the lack of communications systems caused considerable difficulties for responders. It was concluded that responses to hurricanes can be made more effective by having all response communities incident command structure (ICS)-trained with a thorough knowledge of the National Response Plan as it relates to the National Contingency Plan. Ensuring that plans are operational, having clear lines of authority on all hurricane-related issues, and having a robust communications plan were recommended, as well as the ability to respond without communications

Spatial-temporal water quality parameters evaluation of the Santa Rita river (BA with respect to the release of manipueira

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Franklin Delano Porto Júnior

2012-12-01

Full Text Available The watershed of the river Santa Rita includes the towns of Simão and Campinhos, where exists about 150 flour houses. Campinhos is among the largest cassava processing facilities in the region, generating many direct and indirect jobs. Manipueira is a liquid residue originating from the cassava pressing and presents high pollutant potential due to its high amount of glucose and fructose, this potential is 25 times greater than the one from domestic sewer. This work had as objective the evaluation of possible impacts of manipueira release in the water quality of Santa Rita river. For this, the land use map was elaborated and the physiographic characterization developed, besides being performed six campaigns for water samples collection in four sampling points along the river. The obtained results indicated that the watershed is elongated, with low drainage efficiency and it is not prone to flooding. Estimated water quality parameters indicated that organic effluents from Campinhos and Simão impact the values of dissolved oxygen, electrical conductivity, salinity, ammonia, nitrite, nitrate and zinc, suggesting that the water quality of the river Santa Rita is affected by manipueira release. The concentrations of total phosphorus, iron and cooper were superior downstream of the Sewer Treatment Station. The river water was saline in the three sampling points most affected by the release of manipueira.

Operational Philosophy Concerning Manned Spacecraft Cabin Leaks

Science.gov (United States)

DeSimpelaere, Edward

2011-01-01

The last thirty years have seen the Space Shuttle as the prime United States spacecraft for manned spaceflight missions. Many lessons have been learned about spacecraft design and operation throughout these years. Over the next few decades, a large increase of manned spaceflight in the commercial sector is expected. This will result in the exposure of commercial crews and passengers to many of the same risks crews of the Space Shuttle have encountered. One of the more dire situations that can be encountered is the loss of pressure in the habitable volume of the spacecraft during on orbit operations. This is referred to as a cabin leak. This paper seeks to establish a general cabin leak response philosophy with the intent of educating future spacecraft designers and operators. After establishing a relative definition for a cabin leak, the paper covers general descriptions of detection equipment, detection methods, and general operational methods for management of a cabin leak. Subsequently, all these items are addressed from the perspective of the Space Shuttle Program, as this will be of the most value to future spacecraft due to similar operating profiles. Emphasis here is placed upon why and how these methods and philosophies have evolved to meet the Space Shuttle s needs. This includes the core ideas of: considerations of maintaining higher cabin pressures vs. lower cabin pressures, the pros and cons of a system designed to feed the leak with gas from pressurized tanks vs. using pressure suits to protect against lower cabin pressures, timeline and consumables constraints, re-entry considerations with leaks of unknown origin, and the impact the International Space Station (ISS) has had to the standard Space Shuttle cabin leak response philosophy. This last item in itself includes: procedural management differences, hardware considerations, additional capabilities due to the presence of the ISS and its resource, and ISS docking/undocking considerations with a

A Cáritas brasileira e a Economia Popular Solidária: O Agente de Cáritas e a Caridade Libertadora (Brazilian Caritas and the Popular Solidarity Economy: The Agent of Caritas and the Charity Liberating) - DOI: 10.5752/P.2175-5841.2013v11n32p1506

OpenAIRE

Joannes Paulus Silva Forte; Alicia Ferreira Gonçalves

2013-01-01

O presente artigo analisa as ligações entre a Cáritas Brasileira e a Economia Popular Solidária a partir do trabalho do Agente de Cáritas. A problemática central do artigo remete às representações sociais que esses Agentes constroem em seus relatos sobre os princípios da Teologia da Libertação que norteiam os projetos em economia solidária da referida instituição religiosa. A metodologia de base qualitativa e etnográfica consistiu na realização da revisão bibliográfica, consulta a materiais i...

Philosophy, Neuroscience and Education

Science.gov (United States)

Clark, John

2015-01-01

This short note takes two quotations from Snooks' recent editorial on neuroeducation and teases out some further details on the philosophy of neuroscience and neurophilosophy along with consideration of the implications of both for philosophy of education.

The Philosophy of Mathematics Education

DEFF Research Database (Denmark)

mathematics education, and the most relevant modern movements in the philosophy of mathematics. A case study is provided of an emerging research tradition in one country. This is the Hermeneutic strand of research in the philosophy of mathematics education in Brazil. This illustrates one orientation towards......This survey provides a brief and selective overview of research in the philosophy of mathematics education. It asks what makes up the philosophy of mathematics education, what it means, what questions it asks and answers, and what is its overall importance and use? It provides overviews of critical...... research inquiry in the philosophy of mathematics education. It is part of a broader practice of ‘philosophical archaeology’: the uncovering of hidden assumptions and buried ideologies within the concepts and methods of research and practice in mathematics education. An extensive bibliography is also...

The Multiple Life of Nerve Growth Factor: Tribute to Rita Levi-Montalcini (1909-2012

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Luigi Aloe

2013-03-01

Full Text Available At the end of the 19th century, it was envisaged by Santiago Ramon y Cajal, but not, proven, that life at the neuronal level requires trophic support. The proof was obtained in the early 1950's by work initiated by Rita Levi-Montalcini (RLM discovering the nerve growth factor (NGF. Today, NGF and its relatives, collectively designated neurotrophins, are well recognized as mediators of multiple biological phenomena in health and disease, ranging from the neurotrophic through immunotrophic and epitheliotrophic to metabotrophic effects. Consequently, NGF and other neurotrophins are implicated in the pathogenesis of a large spectrum of neuronal and non-neuronal diseases, from Alzheimer's and other neurodegenerative diseases to atherosclerosis and other cardiometabolic diseases. Recent studies demonstrated the therapeutic potentials of NGF in these diseases, including ocular and cutaneous diseases. Furthermore, NGF TrkA receptor antagonists emerged as novel drugs for pain, prostate and breast cancer, melanoma, and urinary bladder syndromes. Altogether, NGF's multiple potential in health and disease is briefly described here.

The multiple life of nerve growth factor: tribute to rita levi-montalcini (1909-2012).

Science.gov (United States)

Aloe, Luigi; Chaldakov, George N

2013-03-01

At the end of the 19(th) century, it was envisaged by Santiago Ramon y Cajal, but not, proven, that life at the neuronal level requires trophic support. The proof was obtained in the early 1950's by work initiated by Rita Levi-Montalcini (RLM) discovering the nerve growth factor (NGF). Today, NGF and its relatives, collectively designated neurotrophins, are well recognized as mediators of multiple biological phenomena in health and disease, ranging from the neurotrophic through immunotrophic and epitheliotrophic to metabotrophic effects. Consequently, NGF and other neurotrophins are implicated in the pathogenesis of a large spectrum of neuronal and non-neuronal diseases, from Alzheimer's and other neurodegenerative diseases to atherosclerosis and other cardiometabolic diseases. Recent studies demonstrated the therapeutic potentials of NGF in these diseases, including ocular and cutaneous diseases. Furthermore, NGF TrkA receptor antagonists emerged as novel drugs for pain, prostate and breast cancer, melanoma, and urinary bladder syndromes. Altogether, NGF's multiple potential in health and disease is briefly described here.

The Concept "System of Philosophy"

DEFF Research Database (Denmark)

Catana, Leo

2005-01-01

of philosophy’ as a methodological tool in the history of philosophy. I shall argue that the interdisciplinary nature of much pre-modern philosophy makes Brucker’s methodological concept ‘system of philosophy’ inadequate, and that we may be better off leaving it behind in our future exploration of pre-modern......In this article I shall examine and discuss the concept ‘system of philosophy’ as a methodological tool in the history of philosophy. I shall do so in two moves. First I shall analyze the historical origin of the concept in the seventeenth and eighteenth centuries. Thereafter I shall undertake...... a discussion of its methodological weaknesses — a discussion, which is not only relevant to the writing of history of philosophy in the seventeenth and eighteenth centuries, but also to the writing of history of philosophy in our times, where the concept remains an important methodological tool. My first move...

Philosophy of Physics

Science.gov (United States)

Crease, Robert P.

2017-10-01

There are some physics controversies that no amount of physics research can answer. Why is doing string theory scientific despite its lack of empirical predictions? How should we interpret quantum mechanics? What is the nature of time and space? What constitutes fundamental physics? One can answer these questions dogmatically by appealing to textbooks or by making rough and ready pronouncements, but the issues behind them can often be significantly clarified by the sort of systematic, critical reflection that philosophy practices. Philosophy comes in several traditions. Three of these-known as 'analytic,' 'pragmatic' and 'continental'-have paid particular attention to physics. This ebook illustrates philosophy of physics in action, and how it can help physics, by using four examples from physics to exhibit the aims and value of these philosophical approaches.

Information Philosophy in China: Professor Wu Kun’s 30 Years of Academic Thinking in Information Philosophy

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Guowu Li

2011-10-01

Full Text Available Professor Wu Kun, from Xi'an Jiaotong University of China, has been studying information philosophy for 30 years. He thinks information conception is one of the most fundamental areas in philosophy and has founded information philosophy. He has done original and pioneering research in information ontology, epistemology, social information theory, information production theory, information evolution theory, information value, and information thinking directions. He is the first scholar to develop a completely new view of theories, systems, and methods about information philosophy.

Dissolved and colloidal trace elements in the Mississippi River delta outflow after Hurricanes Katrina and Rita

Science.gov (United States)

Shim, Moo-Joon; Swarzenski, Peter W.; Shiller, Alan M.

2012-07-01

The Mississippi River delta outflow region is periodically disturbed by tropical weather systems including major hurricanes, which can terminate seasonal bottom water hypoxia and cause the resuspension of shelf bottom sediments which could result in the injection of trace elements into the water column. In the summer of 2005, Hurricanes Katrina and Rita passed over the Louisiana Shelf within a month of each other. Three weeks after Rita, we collected water samples in the Mississippi River delta outflow, examining the distributions of trace elements to study the effect of Hurricanes Katrina and Rita. We observed limited stratification on the shelf and bottom waters that were no longer hypoxic. This resulted, for instance, in bottom water dissolved Mn being lower than is typically observed during hypoxia, but with concentrations still compatible with Mn-O2 trends previously reported. Interestingly, for no element were we able to identify an obvious effect of sediment resuspension on its distribution. In general, elemental distributions were compatible with previous observations in the Mississippi outflow system. Co and Re, which have not been reported for this system previously, showed behavior consistent with other systems: input for Co likely from desorption and conservative mixing for Re. For Cs, an element for which there is little information regarding its estuarine behavior, conservative mixing was also observed. Our filtration method, which allowed us to distinguish the dissolved (<0.02 μm) from colloidal (0.02-0.45 μm) phase, revealed significant colloidal fractions for Fe and Zn, only. For Fe, the colloidal phase was the dominant fraction and was rapidly removed at low salinity. Dissolved Fe, in contrast, persisted out to mid-salinities, being removed in a similar fashion to nitrate. This ability to distinguish the smaller Fe (likely dominantly organically complexed) from larger colloidal suspensates may be useful in better interpreting the bioavailablity

Using the Design for Demise Philosophy to Reduce Casualty Risk Due to Reentering Spacecraft

Science.gov (United States)

Kelley, R. L.

2012-01-01

Recently the reentry of a number of vehicles has garnered public attention due to their risk of human casualty due to fragments surviving reentry. In order to minimize this risk for their vehicles, a number of NASA programs have actively sought to minimize the number of components likely to survive reentry at the end of their spacecraft's life in order to meet and/or exceed NASA safety standards for controlled and uncontrolled reentering vehicles. This philosophy, referred to as "Design for Demise" or D4D, has steadily been adopted, to at least some degree, by numerous programs. The result is that many programs are requesting evaluations of components at the early stages of vehicle design, as they strive to find ways to reduce the number surviving components while ensuring that the components meet the performance requirements of their mission. This paper will discuss some of the methods that have been employed to ensure that the consequences of the vehicle s end-of-life are considered at the beginning of the design process. In addition this paper will discuss the technical challenges overcome, as well as some of the more creative solutions which have been utilized to reduce casualty risk.

Redpath on the Nature of Philosophy

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Robert A. Delfino

2016-03-01

Full Text Available In this article the author discusses Peter A. Redpath’s understanding of the nature of philosophy and his account of how erroneous understandings of philosophy have led to the decline of the West and to the separation of philosophy from modern science and modern science from wisdom. Following Aristotle and St. Thomas Aquinas, Redpath argues that philosophy is a sense realism because it begins in wonder about real things known through the senses. Philosophy presupposes pre-philosophical knowledge, common sense, which consists of principles rooted in sensation that make human experience, sense wonder, and philosophy possible. Philosophy is certain knowledge demonstrated through causes and thus philosophy is the same as science. Redpath understands science as a habit that we acquire through repeated practice. More precisely, a scientific habit is a simple quality of the intellect that enables us to demonstrate (prove the necessary properties of a genus through their causes or principles. In this way, science is the study of the one and the many. Redpath argues that metaphysics is the final cause of the arts and sciences, providing the foundation for all of the arts and sciences and justifying their principles. Finally, he argues that with modernity’s loss of belief in God and its rejection of metaphysics as a science, utopian socialism has become an historical/political substitute for metaphysics.

Science and Philosophy: A Love-Hate Relationship

OpenAIRE

de Haro, Sebastian

2013-01-01

In this paper I review the problematic relationship between science and philosophy; in particular, I will address the question of whether science needs philosophy, and I will offer some positive (if incomplete) perspectives that should be helpful in developing a synergetic relationship between the two. I will review three lines of reasoning often employed in arguing that philosophy is useless for science: a) philosophy's death diagnosis ('philosophy is dead') and what follows from it; b) the ...

Impact of hurricanes katrina and rita on the anesthesiology workforce.

Science.gov (United States)

Hutson, Larry R; Vega, Jorge; Schubert, Armin

2011-01-01

Hurricanes Katrina and Rita impacted a large portion of the medical community in Louisiana. We attempt to determine their impact on the anesthesiology workforce in Louisiana. In May 2006, a survey was mailed to 368 Louisiana anesthesiologists, collecting demographic data, retirement plans, impact of Hurricanes Katrina and Rita, position vacancies, practice conditions, and the general state of healthcare in their area. All 3 anesthesiology residency programs in the state were contacted regarding their recent graduates. The 2010 RAND survey of the anesthesiology workforce was reviewed with respect to findings relevant to the state and region. One hundred seventy surveys were returned, yielding a 46.2% response rate. Among the respondents, 13.9% intended to retire within 5 years and another 24% in 5 to 10 years. Since 2005, 63.9% had seen an increase in their daily caseload, 46.9% saw an increase in work hours, and 36.8% stated that their practices were trying to hire new anesthesiologists and were having difficulty filling these positions. Since 2005, the number of anesthesiology residents in Louisiana had declined by almost 50%, and the number of graduates remaining to practice in Louisiana had decreased by 43% from 7 to 4 annually. Our 2006 survey provided qualitative evidence for a shortage of anesthesiologists in the state of Louisiana after the natural disasters in 2005 that was likely to worsen as residency output plummeted, fewer residents stayed in the state, and projected retirement increased. The regional data from the RAND survey a year later confirmed the impressions from our survey, with an estimate of an anesthesiologist shortage as high as 39% of the workforce. State membership surveys may serve as accurate barometers in the wake of major environmental upheavals affecting regional anesthesiology workforce conditions.

Conversations in African Philosophy

African Journals Online (AJOL)

JONATHAN

Conversational philosophy is articulated by Jonathan O. Chimakonam as the new wave of philosophical practice both in “place” and in “space”. This journal adopts and promotes this approach to philosophizing for African philosophy. Readers are encouraged to submit their conversational piece (maximum of 2000 words) ...

Operational Health Physics-Science or Philosophy?

International Nuclear Information System (INIS)

Carter, M. W.

2004-01-01

Operational health physics is concerned with protecting workers and the public from harm due to ionizing radiation. This requires the application of philosophy (ethics) as well as science. Operational health physics philosophy has been dominated by the ICRP. A particular aspect of ICRP's philosophy that is often misunderstood is (As low as reasonably achievable, economic and social factors being taken into account). (ALARA) Although the ALARA philosophy has been interpreted as a cost-benefit approach it is in fact a risk-benefit approach including social considerations as the ICRP has emphasised from time to time. A recent report has accused the ICRP of using a discarded philosophical approach, namely Utilitarianism, as a result of which its recommendations are unethical. The report suggests that a (rights) based philosophy such as Rawls' Theory of Justice would be a more appropriate basis. This paper discusses this accusation, considers some relevant philosophies and concludes that the accusation is not valid and that ICRP's recommendations are ethical but are frequently misinterpreted. (Author)

Particle physics and philosophy

Energy Technology Data Exchange (ETDEWEB)

Sakata, S.

1984-01-01

The philosophy of dialectical materialism is applied to the history of the discovery of building blocks of matter. Engels' theory was adapted by Taketani to describe the cognizance of different levels of material structures. This philosophy was used to construct the composite Sakata model of hadrons in the early sixties.

Philosophy of biology: naturalistic or transcendental?

Science.gov (United States)

Kolen, Filip; Van de Vijver, Gertrudis

2007-01-01

The aim of this article is to clarify the meaning of a naturalistic position within philosophy of biology, against the background of an alternative view, founded on the basic insights of transcendental philosophy. It is argued that the apparently minimal and neutral constraints naturalism imposes on philosophy of science turn out to involve a quite heavily constraining metaphysics, due to the naturalism's fundamental neglect of its own perspective. Because of its intrinsic sensitivity to perspectivity and historicity, transcendental philosophy can avoid this type of hidden metaphysics.

The monochromatic imaging mode of a RITA-type neutron spectrometer

International Nuclear Information System (INIS)

Bahl, C.R.H.; Andersen, P.; Klausen, S.N.; Lefmann, K.

2004-01-01

The imaging monochromatic mode of a neutron spectrometer with a multi-bladed RITA analyser system is so far unexplored. We present analytical calculations that define the mode. It is shown that the mode can be realised for PG (0 0 2) analyser crystals, from incident energies of about 3.2 meV and up, allowing the important cases of 3.7, 5.0 and 13.7 meV. Due to beam divergence, the neutron rays from neighbouring analyser blades are found to overlap slightly. Hence, the optimal use of the monochromatic imaging mode would be found by employing an adjustable radial collimator to limit the spread of the ray from each analyser blade

The monochromatic imaging mode of a RITA-type neutron spectrometer

Energy Technology Data Exchange (ETDEWEB)

Bahl, C.R.H. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark) and Department of Physics, Technical University of Denmark, DK-2800 Lyngby (Denmark)]. E-mail: christian.bahl@risoe.dk; Andersen, P. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Niels Bohr Institute for Astronomy, Physics and Geophysics, University of Copenhagen, DK-2100 Copenhagen (Denmark); Klausen, S.N. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Lefmann, K. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark)

2004-12-01

The imaging monochromatic mode of a neutron spectrometer with a multi-bladed RITA analyser system is so far unexplored. We present analytical calculations that define the mode. It is shown that the mode can be realised for PG (0 0 2) analyser crystals, from incident energies of about 3.2 meV and up, allowing the important cases of 3.7, 5.0 and 13.7 meV. Due to beam divergence, the neutron rays from neighbouring analyser blades are found to overlap slightly. Hence, the optimal use of the monochromatic imaging mode would be found by employing an adjustable radial collimator to limit the spread of the ray from each analyser blade.

Application of the Lean Office philosophy and mapping of the value stream in the process of designing the banking units of a financial company

Directory of Open Access Journals (Sweden)

Nelson Antônio Calsavara

2016-09-01

Full Text Available The purpose of this study is to conduct a critical analysis of the effects of Lean Office on the design process of the banking units of a financial company and how the implementation of this philosophy may contribute to productivity, thus reducing implementation time. A literature review of the Toyota Production System was conducted, as well as studies on its methods, with advancement to lean thinking and consistent application of Lean philosophies in services and Office. A bibliographic and documentary survey of the Lean processes and procedures for opening bank branches was taken. A Current State Map was developed, modeling the current operating procedures. Soon after the identification and analysis of waste, proposals were presented for reducing deadlines and eliminating and grouping stages, with consequent development of the Future State Map, implementation and monitoring of stages, and the measurement of estimated time gains in operation, demonstrating an estimated 45% reduction, in days, from start to end of the process, concluding that the implementation of the Lean Office philosophy contributed to the process.

Why still philosophy?: Once again

Directory of Open Access Journals (Sweden)

Krstić Predrag

2007-01-01

Full Text Available The intention of this paper is to revisit, once again the question asked by Adorno and Habermas and other contemporary thinkers under different headings few decades ago. The author is suggesting that nowadays philosophy requires a final departure from the idea of having single and perennial face, and that this would not only allow, but also enable philosophy to test its various faces freely, that is, without norm or limit set in advance. At the same time, by creating such ′liberal′ climate philosophy would no longer be frightened by the possible answer, and hence would no longer dramatize the very question of ′why still?′. Even if philosophy turns out to be far less than the mission it once bestowed upon itself.

Mapping Hurricane Rita inland storm tide

Science.gov (United States)

Berenbrock, Charles; Mason, Jr., Robert R.; Blanchard, Stephen F.; Simonovic, Slobodan P.

2009-01-01

Flood-inundation data are most useful for decision makers when presented in the context of maps of effected communities and (or) areas. But because the data are scarce and rarely cover the full extent of the flooding, interpolation and extrapolation of the information are needed. Many geographic information systems (GIS) provide various interpolation tools, but these tools often ignore the effects of the topographic and hydraulic features that influence flooding. A barrier mapping method was developed to improve maps of storm tide produced by Hurricane Rita. Maps were developed for the maximum storm tide and at 3-hour intervals from midnight (0000 hour) through noon (1200 hour) on September 24, 2005. The improved maps depict storm-tide elevations and the extent of flooding. The extent of storm-tide inundation from the improved maximum storm-tide map was compared to the extent of flood-inundation from a map prepared by the Federal Emergency Management Agency (FEMA). The boundaries from these two maps generally compared quite well especially along the Calcasieu River. Also a cross-section profile that parallels the Louisiana coast was developed from the maximum storm-tide map and included FEMA high-water marks.

Rorty, Pragmatism, and Analytic Philosophy

Directory of Open Access Journals (Sweden)

Cheryl Misak

2013-07-01

Full Text Available One of Richard Rorty's legacies is to have put a Jamesian version of pragmatism on the contemporary philosophical map. Part of his argument has been that pragmatism and analytic philosophy are set against each other, with pragmatism almost having been killed off by the reigning analytic philosophy. The argument of this paper is that there is a better and more interesting reading of both the history of pragmatism and the history of analytic philosophy.

Particle physics and philosophy

International Nuclear Information System (INIS)

Sakata, Shoichi.

1984-01-01

The philosophy of dialectical materialism is applied to the history of the discovery of building blocks of matter. Engels' theory was adapted by Taketani to describe the cognizance of different levels of material structures. This philosophy was used to construct the composite Sakata model of hadrons in the early sixties. (D.Gy.)

Counseling and Transcendental Philosophy

Science.gov (United States)

Donceel, Joseph

1971-01-01

An acquaintance with the different philosophies of human nature is an invaluable asset for counseling. The author presents a modern Christian concept of man with emphasis on contributions of Aristotle and St. Thomas Aquinas and elements from modern philosophy. Its two main concerns are man's spirit and man's knowledge and will. (Author/CG)

Trends in African philosophy

African Journals Online (AJOL)

JONATHAN

In the contention of Oladipo (2006), the debate on the idea of. African philosophy which has been divided into trends or schools, dates back to the 1960's and 70's, which constitute the modern epoch of African philosophy, when some African thinkers began to question the perspective that traditional African beliefs and.

Legal Philosophy - Five Questions

DEFF Research Database (Denmark)

This collection gathers together a host of the most eminent contemporary legal philosophers, who writes about their take on legal philosophy, its fundamental questions and potential.......This collection gathers together a host of the most eminent contemporary legal philosophers, who writes about their take on legal philosophy, its fundamental questions and potential....

Philosophy of Science, with Special Consideration Given to Behaviorism as the Philosophy of the Science of Behavior

Science.gov (United States)

Moore, J.

2010-01-01

The philosophy of science is the branch of philosophy that critically examines the foundations, assumptions, methods, products, and implications of the activity called science. The present sketch reviews the historical development of the philosophy of science, representative individuals in the field, and topics of long-standing interest. The…

Later Wittgenstein and the Philosophy of Religion

DEFF Research Database (Denmark)

Hansen, Stig Børsen

2010-01-01

This article sets out by distinguishing Wittgenstein’s own views in the philosophy of religion from a school of thought in the philosophy of religion that relies on later Wittgenstein’s philosophy of language. After a survey of distinguishing features of Wittgenstein’s later philosophy, the third...... section explores Wittgenstein’s treatment of Frazer’s account of magic among primitive peoples. The following section offers an account of Wittgensteinian philosophy of religion, including the use of the notions of a language game and superstition. I conclude by criticizing a very influential argument...

ENVIRONMENTAL PHILOSOPHY AND ECOLOGICAL CULTURE

Directory of Open Access Journals (Sweden)

Kalimat M. Alilova

2017-01-01

Full Text Available Aim. The aim of the research is to study environmental problems related to the decline of culture, the importance of philosophy in overcoming private and personal interests as well as the unilateral approach of man in his relationship to nature. The study shows how philosophy can participate in the formation of ecological culture, a new ecological consciousness in man, while ecological culture is called upon to resist technocratic stereotypes and the course of history was aimed at preventing the biosphere from becoming deserted. Discussion. On the basis of the analysis of literary sources, we used the method of socio-cultural and socio-natural approaches based on the possibility of philosophy to introduce a new life into culture, new ecological values and new ecological principles. To solve these problems, environmental philosophy develops new theories. Representatives of different cultures, ethnic groups, nations, religions must learn to coexist with each other. We consider philosophy as a means of teaching rapprochement between peoples and creating new opportunities for understanding and improving the environmental situation. Cultural development makes it possible to assess the level of a man’s knowledge of nature, himself and the world around him. Ecological culture is a way of connecting man with nature on the basis of deeper knowledge and understanding. Philosophy says that you cannot move away from nature and be lauded over it since this will destroy culture. Rational doctrines tend to put a person above other living beings so the synthesis of philosophy with culture can have a positive ecological meaning. Conclusion. The findings obtained can be recommended for practical use in schools, starting from primary school, as well as in secondary special educational institutions and universities. It is necessary to work on the motivation and values of people, develop a common and ecological culture. Only a cultured person can move from

Investigating Talent Management Philosophies

Directory of Open Access Journals (Sweden)

Urbancova Hana

2015-09-01

Full Text Available This study, motivated by the recognition that organizational performance and success always hinges on employee competencies and management’s skill in utilizing their potentials, focuses on one of the key factors in organizational efficiency: the possibilities of development of talented employees within Czech organizations. The data was collected via two quantitative studies. The first study involved 100 organizations from every economic sector with a main focus on the topic from the organization’s perspective. The second study explored the approach from employees’ perspective. Our analysis shows that different talent management philosophies are used in practice. Almost half of the sample use inclusive and stable philosophy, 11% inclusive and developable philosophy and almost 10% exclusive and developable philosophy. Employees are mostly developed in generally recommended areas without any consideration for the specific individual’s characteristics or related opportunities. It is a stable approach. Limitations of this study may be found in the focus on analysis outcomes - on practitioners in particular. The present findings provide a basis for future hypotheses and research in this area.

Operational Health Physics-Science or Philosophy?

Energy Technology Data Exchange (ETDEWEB)

Carter, M. W.

2004-07-01

Operational health physics is concerned with protecting workers and the public from harm due to ionizing radiation. This requires the application of philosophy (ethics) as well as science. Operational health physics philosophy has been dominated by the ICRP. A particular aspect of ICRP's philosophy that is often misunderstood is (As low as reasonably achievable, economic and social factors being taken into account). (ALARA) Although the ALARA philosophy has been interpreted as a cost-benefit approach it is in fact a risk-benefit approach including social considerations as the ICRP has emphasised from time to time. A recent report has accused the ICRP of using a discarded philosophical approach, namely Utilitarianism, as a result of which its recommendations are unethical. The report suggests that a (rights) based philosophy such as Rawls' Theory of Justice would be a more appropriate basis. This paper discusses this accusation, considers some relevant philosophies and concludes that the accusation is not valid and that ICRP's recommendations are ethical but are frequently misinterpreted. (Author)

Novel Approaches to Manipulating Bacterial Pathogen Biofilms: Whole-Systems Design Philosophy and Steering Microbial Evolution.

Science.gov (United States)

Penn, Alexandra S

2016-01-01

Understanding and manipulating bacterial biofilms is crucial in medicine, ecology and agriculture and has potential applications in bioproduction, bioremediation and bioenergy. Biofilms often resist standard therapies and the need to develop new means of intervention provides an opportunity to fundamentally rethink our strategies. Conventional approaches to working with biological systems are, for the most part, "brute force", attempting to effect control in an input and effort intensive manner and are often insufficient when dealing with the inherent non-linearity and complexity of living systems. Biological systems, by their very nature, are dynamic, adaptive and resilient and require management tools that interact with dynamic processes rather than inert artefacts. I present an overview of a novel engineering philosophy which aims to exploit rather than fight those properties, and hence provide a more efficient and robust alternative. Based on a combination of evolutionary theory and whole-systems design, its essence is what I will call systems aikido; the basic principle of aikido being to interact with the momentum of an attacker and redirect it with minimal energy expenditure, using the opponent's energy rather than one's own. In more conventional terms, this translates to a philosophy of equilibrium engineering, manipulating systems' own self-organisation and evolution so that the evolutionarily or dynamically stable state corresponds to a function which we require. I illustrate these ideas with a description of a proposed manipulation of environmental conditions to alter the stability of co-operation in the context of Pseudomonas aeruginosa biofilm infection of the cystic fibrosis lung.

Philosophy of Data: Why?

Science.gov (United States)

Furner, Jonathan

2017-01-01

Philosophy of data should not be dismissed as a cluster of scholastic puzzles whose solutions are of limited practical value. On the contrary, philosophy of data should be recognized as constituting the core of a field of data studies that is informed by, but far from equivalent to, statistics, computer science, and library and information studies.

Crossing Canadian Cultural Borders: A study of the Aboriginal/White Stereotypical Relations in George Ryga's The Ecstasy of Rita Joe

Directory of Open Access Journals (Sweden)

Maram M. Samman

2017-12-01

Full Text Available This paper traces the intercultural journey of a young Aboriginal girl into the hegemonic white society. Rita Joe crossed the imaginary border that separates her reserve from the other Canadian society living in the urban developed city. Through this play, George Ryga aims at achieving liberation and social equality for the Aboriginals who are considered a colonized minority in their land. The research illustrates how Ryga represented his personal version of the colonial Aboriginal history to provide an empowering body narrative that supports their identity in the present and resists the erosion of their culture and tradition. The play makes very strong statements to preserve the family, history and local heritage against this forced assimilation. It tells the truth as its playwright saw it. The play is about the trail of Rita Joe after she moved from her reserve in pursuit of the illusion of the city where she thought she would find freedom and social equality. In fact the audience and the readers are all on trial. Ryga is pointing fingers at everyone who is responsible for the plights of the Aboriginals as it is clear in the play. He questions the Whites’ stereotypical stand against the Aboriginals. The play is a direct criticism of the political, social and cultural systems in Canada. The paper reveals Aboriginals' acts of opposition to racism, assimilation and colonization as represented in The Ecstasy of Rita Joe.

Chinese Traditional Philosophy and Indigenous Management Research

DEFF Research Database (Denmark)

Li, Xin

2013-01-01

This paper focuses on three key notions of Chinese traditional philosophy, i.e., Zhongyong, Yin Yang, and Wu, pointing out the possible mistakes in Prof. Peter Ping Li's arguments as well as some questions that are often neglected and taken for granted. The author posits, Chinese traditional...... philosophy is a system of thought distinct from the Western philosophy; while the Western philosophy is mainly concerned about the True, i.e., the objective knowledge of the world, the aim of Chinese traditional philosophy is the pursuit of the Good, i.e., the unification of heaven and human....

An instrumentation and control philosophy for high-level nuclear waste processing facilities

International Nuclear Information System (INIS)

Weigle, D.H.

1990-01-01

The purpose of this paper is to present an instrumentation and control philosophy which may be applied to high-level nuclear waste processing facilities. This philosophy describes the recommended criteria for automatic/manual control, remote/local control, remote/local display, diagnostic instrumentation, interlocks, alarm levels, and redundancy. Due to the hazardous nature of the process constituents of a high-level nuclear waste processing facility, it is imperative that safety and control features required for accident-free operation and maintenance be incorporated. A well-instrumented and controlled process, while initially more expensive in capital and design costs, is generally safer and less expensive to operate. When the long term cost savings of a well designed process is coupled with the high savings enjoyed by accident avoidance, the benefits far outweigh the initial capital and design costs

Science and philosophy in Deleuze

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Krtolica Igor

2015-01-01

Full Text Available Deleuze will not wait until he had completed his works to frame and formulate a theory on the relation between philosophy and science. The first articulations of this question are already present as early as the 1950s and 1960s in the studies on Bergson and Nietzsche, and then in Difference and repetition as well as in The Logic of Sense. It is also true that this question will be specifically developed in 1991 in What Is Philosophy? But throughout his work, the main thrust would proceed. This issue, it seems, comprises three main aspects: in the first place, in a polemic against the neo-Kantian epistemological legacy, it primarily consists in denying the critical definition of philosophy as being a ‘reflection on scientific knowledge’ to replace it by a conception drawn from Bergson’s expressionist ontology that places science and philosophy on both sides of the being; secondly, in an attempt to restore the concept of dialectics, it consists in making the dialectics of ideas the communal sphere of both science and philosophy; thirdly, aiming to specify every form of thinking, it consists in shaping how each expresses its ideas or its problems with its own signs. These three aspects, it seems, can frame the overall conception Deleuze formed of the link between science and philosophy. We shall successively analyze them, exclusively considering the first period of Deleuze’s work, which is to say the pre-guattarian publications.

Qualitative tools and experimental philosophy

Science.gov (United States)

Andow, James

2016-01-01

Abstract Experimental philosophy brings empirical methods to philosophy. These methods are used to probe how people think about philosophically interesting things such as knowledge, morality, and freedom. This paper explores the contribution that qualitative methods have to make in this enterprise. I argue that qualitative methods have the potential to make a much greater contribution than they have so far. Along the way, I acknowledge a few types of resistance that proponents of qualitative methods in experimental philosophy might encounter, and provide reasons to think they are ill-founded. PMID:28392629

How new is the new philosophy of psychiatry?

Directory of Open Access Journals (Sweden)

Denys Damiaan

2007-10-01

Full Text Available Abstract In their recent paper, Natalie Banner and Tim Thornton evaluate seven volumes of the Oxford University Press series “International Perspectives in Philosophy and Psychiatry,” an international book series begun in 2003 focusing on the emerging interdisciplinary field at the interface of philosophy and psychiatry. According to Natalie Banner and Tim Thornton, the series represents a clear indication that the interdisciplinary field of philosophy of psychiatry has been flourishing lately. Philosophers and psychiatrists face a “new philosophy of psychiatry”. However, the optimism which the “new” philosophy of psychiatry celebrates is precisely the exiling of philosophy from the foundations of psychiatry. The 150 year old belief that psychopathology cannot do without philosophical reflection has virtually disappeared from common psychiatric education and daily clinical practice. Though the discipline of psychiatry is particularly suited to contributions from philosophy, the impact of philosophy on psychiatry nowadays remains limited. With some exceptions, philosophical papers are embedded in a philosophical context inscrutable to ordinary psychiatrists. Much current philosophical work is perceived by psychiatrists as negativistic. I would encourage the field of psychiatry to incorporate once again basic philosophical attitudes which render possible true dialogue with philosophy and enrich both disciplines. The views developed here should not discredit the value and importance of Natalie Banner and Tim Thornton’s paper and the excellent series “International Perspectives in Philosophy and Psychiatry.” As Jaspers said “Everybody inclined to disregard philosophy will be overwhelmed by philosophy in an unperceived way”.

How new is the new philosophy of psychiatry?

Science.gov (United States)

Denys, Damiaan

2007-01-01

In their recent paper, Natalie Banner and Tim Thornton evaluate seven volumes of the Oxford University Press series “International Perspectives in Philosophy and Psychiatry,” an international book series begun in 2003 focusing on the emerging interdisciplinary field at the interface of philosophy and psychiatry. According to Natalie Banner and Tim Thornton, the series represents a clear indication that the interdisciplinary field of philosophy of psychiatry has been flourishing lately. Philosophers and psychiatrists face a “new philosophy of psychiatry”. However, the optimism which the “new” philosophy of psychiatry celebrates is precisely the exiling of philosophy from the foundations of psychiatry. The 150 year old belief that psychopathology cannot do without philosophical reflection has virtually disappeared from common psychiatric education and daily clinical practice. Though the discipline of psychiatry is particularly suited to contributions from philosophy, the impact of philosophy on psychiatry nowadays remains limited. With some exceptions, philosophical papers are embedded in a philosophical context inscrutable to ordinary psychiatrists. Much current philosophical work is perceived by psychiatrists as negativistic. I would encourage the field of psychiatry to incorporate once again basic philosophical attitudes which render possible true dialogue with philosophy and enrich both disciplines. The views developed here should not discredit the value and importance of Natalie Banner and Tim Thornton’s paper and the excellent series “International Perspectives in Philosophy and Psychiatry.” As Jaspers said “Everybody inclined to disregard philosophy will be overwhelmed by philosophy in an unperceived way”. PMID:17949505

Environmental Impact Report from Santa Rita Hydroelectric Power Plant (Minas Gerais State - Brazil): technical strategic for its elaboration

International Nuclear Information System (INIS)

Souza, J.A. de; Marques Neto, F.P.

1989-01-01

The steps for developing the technical strategies used on the elaboration of Environmental Impact Report from Santa Rita Hydroelectric Power Plant, Minas Gerais State, are described, including the influence area, technical requirements, impact identification, technical selection of mitigative measures, impact meaning and strategy for evaluating the identified impacts. (C.G.C.)

Mapping and Visualization of Storm-Surge Dynamics for Hurricane Katrina and Hurricane Rita

Science.gov (United States)

Gesch, Dean B.

2009-01-01

The damages caused by the storm surges from Hurricane Katrina and Hurricane Rita were significant and occurred over broad areas. Storm-surge maps are among the most useful geospatial datasets for hurricane recovery, impact assessments, and mitigation planning for future storms. Surveyed high-water marks were used to generate a maximum storm-surge surface for Hurricane Katrina extending from eastern Louisiana to Mobile Bay, Alabama. The interpolated surface was intersected with high-resolution lidar elevation data covering the study area to produce a highly detailed digital storm-surge inundation map. The storm-surge dataset and related data are available for display and query in a Web-based viewer application. A unique water-level dataset from a network of portable pressure sensors deployed in the days just prior to Hurricane Rita's landfall captured the hurricane's storm surge. The recorded sensor data provided water-level measurements with a very high temporal resolution at surveyed point locations. The resulting dataset was used to generate a time series of storm-surge surfaces that documents the surge dynamics in a new, spatially explicit way. The temporal information contained in the multiple storm-surge surfaces can be visualized in a number of ways to portray how the surge interacted with and was affected by land surface features. Spatially explicit storm-surge products can be useful for a variety of hurricane impact assessments, especially studies of wetland and land changes where knowledge of the extent and magnitude of storm-surge flooding is critical.

Gilson, Krapiec and Christian Philosophy Today

Directory of Open Access Journals (Sweden)

Pawel Tarasiewicz

2015-12-01

Full Text Available The author undertakes an attempt to answer the following question: is Christian philosophy possible today? The question seems to be of great importance due to the fact that what Christians who try to do philosophy usually encounter is bitter criticism which comes to them from two sides at once: that of academy and that of the Church. In short, for academy their philosophy is too Christian, and for the Church it is too academic. Being indebted to the insights of Étienne Gilson and Mieczyslaw A. Krapiec (the original Polish spelling: Mieczysław Albert Krąpiec, pronounced: myechisuaf albert krompyetz, the author comes to the conclusion thatChristian philosophy is possible today only if: 1 it isnot identified with the art of persuasion, as its final end lies in gaining understanding rather than being convincing, 2 itis the work of a Christian, and 3 it has thereal world as its object and metaphysics as its method. ForChristian philosophy—which in essence consists indoing philosophy by Christians in order to get morerational understanding of their religious faith—shouldbe identified with theperfection of the intellect achieved by practicingthe classical philosophy of being.

Kierkegaard's Philosophy: Implications for Counseling.

Science.gov (United States)

Dopson, Lorraine; Gade, Eldon

1981-01-01

Discusses how the philosophy of Soren Kierkegaard can provide useful guidelines for the study of the counseling process. Compares Kierkegaard's philosophy with selected contributions of Freud, Skinner, Rogers, and May and with four common themes of counseling and psychotherapy. (Author)

Adequacy of power-to-volume scaling philosophy to simulate natural circulation in Integral Test Facilities

International Nuclear Information System (INIS)

Nayak, A.K.; Vijayan, P.K.; Saha, D.; Venkat Raj, V.; Aritomi, Masanori

1998-01-01

Theoretical and experimental investigations were carried out to study the adequacy of power-to-volume scaling philosophy for the simulation of natural circulation and to establish the scaling philosophy applicable for the design of the Integral Test Facility (ITF-AHWR) for the Indian Advanced Heavy Water Reactor (AHWR). The results indicate that a reduction in the flow channel diameter of the scaled facility as required by the power-to-volume scaling philosophy may affect the simulation of natural circulation behaviour of the prototype plants. This is caused by the distortions due to the inability to simulate the frictional resistance of the scaled facility. Hence, it is recommended that the flow channel diameter of the scaled facility should be as close as possible to the prototype. This was verified by comparing the natural circulation behaviour of a prototype 220 MWe Indian PHWR and its scaled facility (FISBE-1) designed based on power-to-volume scaling philosophy. It is suggested from examinations using a mathematical model and a computer code that the FISBE-1 simulates the steady state and the general trend of transient natural circulation behaviour of the prototype reactor adequately. Finally the proposed scaling method was applied for the design of the ITF-AHWR. (author)

Usefulness of the admission electrocardiogram to predict long-term outcomes after non-ST-elevation acute coronary syndrome (from the FRISC II, ICTUS, and RITA-3 [FIR] Trials)

DEFF Research Database (Denmark)

Damman, Peter; Holmvang, Lene; Tijssen, Jan G P

2012-01-01

Instability in Coronary Artery Disease (FRISC II), Invasive Versus Conservative Treatment in Unstable Coronary Syndromes (ICTUS), and Randomized Intervention Trial of Unstable Angina 3 (RITA-3) patient-pooled database, 5,420 patients with NSTE-ACS with qualitative ECG data, of whom 2,901 had quantitative data...... the addition of quantitative characteristics to a model including qualitative characteristics. In conclusion, in the FRISC II, ICTUS, and RITA-3 NSTE-ACS patient-pooled data set, admission ECG characteristics provided long-term prognostic value for cardiovascular death or myocardial infarction. Quantitative...

Contemporary African philosophy: emergent issues and challenges ...

African Journals Online (AJOL)

... all philosophies remain context-dependent and cultureoriented. A contrary view ignores the proper nature of philosophy. A new phenomenon confronts currently confronts all comers to contemporary African philosophy: an expansive vision of African philosophical discourse. Contemporary African philosophers attempt to ...

Doing Philosophy Effectively: Student Learning in Classroom Teaching.

Science.gov (United States)

Kienstra, Natascha; Imants, Jeroen; Karskens, Machiel; van der Heijden, Peter G M

2015-01-01

An important aim of teaching philosophy in Dutch secondary schools is to learn about philosophy (i.e., the great philosophers) by doing philosophy. We examined doing philosophy and focused specifically on the relationship between student learning activities and teacher behavior; in doing so, a qualitative cross-case analysis of eight philosophy lessons was performed. The effectiveness of doing philosophy was operationalized into five learning activities comprising rationalizing, analyzing, testing, producing criticism, and reflecting, and scored by means of qualitative graphical time registration. Using CA we find a quantitative one-dimensional scale for the lessons that contrasts lessons that are more and less effective in terms of learning and teaching. A relationship was found between teaching by teachers and doing philosophy by students. In particular we found students to produce a higher level of doing philosophy with teachers who chose to organize a philosophical discussion with shared guidance by the teacher together with the students.

Philosophy of Education: Becoming Less Western, More African?

Science.gov (United States)

Enslin, Penny; Horsthemke, Kai

2016-01-01

Posing the question "How diverse is philosophy of education in the West?" this paper responds to two recent defences of African philosophy of education which endorse its communitarianism and oppose individualism in Western philosophy of education. After outlining Thaddeus Metz's argument that Western philosophy of education should become…

Philosophy of Research in Applied Linguistics

OpenAIRE

Mohammad Ali Torabi

2011-01-01

The term  “ philosophy of research in applied linguistics” may be considered to cover a wide range of academically and philosophically important issues that have recently begun to capture the attention of scholars in research programs in their efforts, on the one hand, to reflect upon how they have traditionally approached their scientific practices and, on the other, to reconsider and redefine their research priorities in the light of new findings and revise their methodologies and designs i...

Philosophy and the front line of science.

Science.gov (United States)

Pernu, Tuomas K

2008-03-01

According to one traditional view, empirical science is necessarily preceded by philosophical analysis. Yet the relevance of philosophy is often doubted by those engaged in empirical sciences. I argue that these doubts can be substantiated by two theoretical problems that the traditional conception of philosophy is bound to face. First, there is a strong normative etiology to philosophical problems, theories, and notions that is dfficult to reconcile with descriptive empirical study. Second, conceptual analysis (a role that is typically assigned to philosophy) seems to lose its object of study if it is granted that terms do not have purely conceptual meanings detached from their actual use in empirical sciences. These problems are particularly acute to the current naturalistic philosophy of science. I suggest a more concrete integration of philosophy and the sciences as a possible way of making philosophy of science have more impact.

French PWR safety philosophy

International Nuclear Information System (INIS)

Conte, M.

1986-05-01

Increasing knowledge and lessons learned from starting and operating experience of French nuclear power plants, completed by the experience learned from the operation of foreign reactors, has contributed to the improvement of French PWR design and safety philosophy. Based on a deterministic approach, the French safety analysis was progressively completed by a probabilistic approach, each of them having possibilities and limits. As a consequence of the global risk objective set in 1977 for nuclear reactors, safety analysis was extended to the evaluation of events more complex than the conventional ones, and later to the evaluation of the feasibility of the offsite emergency plans in case of severe accidents

Traumatic Loss and Natural Disaster: A Case Study of a School-Based Response to Hurricanes Katrina and Rita

Science.gov (United States)

Clettenberg, Stacey; Gentry, Judy; Held, Matthew; Mock, Lou Ann

2011-01-01

This article tracks the trajectory and impact of Hurricanes Katrina and Rita on the communities of Houston/Harris County, Texas, USA, the schools, children, and families; along with the community partnerships that addressed the trauma and upheaval. Following the influx of individuals and families who were displaced by Hurricanes Katrina and Rita…

Dissolved and colloidal trace elements in the Mississippi River Delta outflow after Hurricanes Katrina and Rita

Science.gov (United States)

Shim, Moo-Joon; Swarzenski, Peter W.; Shiller, Alan M.

2012-01-01

The Mississippi River delta outflow region is periodically disturbed by tropical weather systems including major hurricanes, which can terminate seasonal bottom water hypoxia and cause the resuspension of shelf bottom sediments which could result in the injection of trace elements into the water column. In the summer of 2005, Hurricanes Katrina and Rita passed over the Louisiana Shelf within a month of each other. Three weeks after Rita, we collected water samples in the Mississippi River delta outflow, examining the distributions of trace elements to study the effect of Hurricanes Katrina and Rita. We observed limited stratification on the shelf and bottom waters that were no longer hypoxic. This resulted, for instance, in bottom water dissolved Mn being lower than is typically observed during hypoxia, but with concentrations still compatible with Mn–O2 trends previously reported. Interestingly, for no element were we able to identify an obvious effect of sediment resuspension on its distribution. In general, elemental distributions were compatible with previous observations in the Mississippi outflow system. Co and Re, which have not been reported for this system previously, showed behavior consistent with other systems: input for Co likely from desorption and conservative mixing for Re. For Cs, an element for which there is little information regarding its estuarine behavior, conservative mixing was also observed. Our filtration method, which allowed us to distinguish the dissolved (<0.02 μm) from colloidal (0.02–0.45 μm) phase, revealed significant colloidal fractions for Fe and Zn, only. For Fe, the colloidal phase was the dominant fraction and was rapidly removed at low salinity. Dissolved Fe, in contrast, persisted out to mid-salinities, being removed in a similar fashion to nitrate. This ability to distinguish the smaller Fe (likely dominantly organically complexed) from larger colloidal suspensates may be useful in better interpreting the

Some Main Features of Wittgenstein´s Philosophy

DEFF Research Database (Denmark)

Brock, Steen

Two chapters from a book manuscript, where four parts of Wittgenstein´s philosophy are systematically interconnected, philosophy of language, mathematics, psychology and natural science......Two chapters from a book manuscript, where four parts of Wittgenstein´s philosophy are systematically interconnected, philosophy of language, mathematics, psychology and natural science...

[Jena philosophies of nature around 1800].

Science.gov (United States)

Breidbach, O

2000-01-01

This paper describes the situation and the outline of positions in philosophy of nature in Jena about 1800, in focusing on research other than the key figures Schelling and Hegel. In 1789, Schelling introduced philosophy of nature into the course program of Jena University. Already in 1800, two young scientists--a mathematician (Fischer) and a physiologist--reacted, announcing lectures on Schellingian topics. But only in late 1802, younger philosophers offered courses on those topics. From 1802 onwards, lectures were announced by Schad, Krause, Henrici, Hegel, Oken and the botanist Schelver. Apart from the Fisher lecture from 1800, the program of these presentations was based on Schellingian principles. Analyses of the ideas of Schad, Krause and Schelver show that, about 1800, philosophy of nature in Jena conserved basic ideas of the early philosophy of nature of Schelling. Thus, philosophy of nature in this period of Jena University seemed to follow just one line of reasoning.

Classroom Teacher's Adherence to Philosophy and Ethics of Home ...

African Journals Online (AJOL)

This study analyzed and discussed the philosophy and goals of education, evaluating them on how classroom teachers adhere to the ethics of home economics for sustainable development in Anambra state, Nigeria. A descriptive survey design was used and the sample, randomly selected, was made up of two hundred ...

Empirical Philosophy of Science

DEFF Research Database (Denmark)

Mansnerus, Erika; Wagenknecht, Susann

2015-01-01

knowledge takes place through the integration of the empirical or historical research into the philosophical studies, as Chang, Nersessian, Thagard and Schickore argue in their work. Building upon their contributions we will develop a blueprint for an Empirical Philosophy of Science that draws upon...... qualitative methods from the social sciences in order to advance our philosophical understanding of science in practice. We will regard the relationship between philosophical conceptualization and empirical data as an iterative dialogue between theory and data, which is guided by a particular ‘feeling with......Empirical insights are proven fruitful for the advancement of Philosophy of Science, but the integration of philosophical concepts and empirical data poses considerable methodological challenges. Debates in Integrated History and Philosophy of Science suggest that the advancement of philosophical...

An introductory course in philosophy of medicine.

Science.gov (United States)

Rudnick, A

2004-06-01

Philosophy of medicine, narrowly defined as ontology and epistemology of medicine, is a well developed research field, yet education in this field is less well developed. The aim of this paper is to present an educational development in philosophy of medicine-an introductory course in philosophy of medicine. Central features of the course are described. Participants (medical undergraduate students) scored high on average. The conclusion is that further such educational ventures in philosophy of medicine should be developed and implemented.

A Companion to the Philosophy of Technology

DEFF Research Database (Denmark)

Friis, Jan Kyrre Berg O.; Pedersen, Stig Andur; Hendricks, Vincent F.

The aim of philosophy of technology is to help us understand technology's complex interrelationships with the environment, society, culture - and with our very existence. A Companion to the Philosophy of Technology is the first comprehensive, authoritative reference source for this burgeoning...... those of the humanities, social studies, natural science, sociology, psychology, and engineering sciences and reflect a diversity of philosophical traditions such as pragmatism, analytical philosophy, and phenomenology. Erudite and authoritative, A Companion to the Philosophy of Technology is a major...

Philosophy as the Wisdom of Love

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Cicovacki Predrag

2017-06-01

Full Text Available The author argues that love should play a central role in philosophy (and ethics. In the past, philosophical practice has been too narrowly defined by theory and explanation. Although unquestionably important, they do not belong to the very core of our philosophizing. Philosophy is primarily a way of life, centered on the soul and the development of our humanity – in its most diverse aspects and to its utmost potential. For such a life to be possible, love must play a central role in philosophy and philosophy should be understood not in the traditional sense as “the love of wisdom,” but in a new way – as the wisdom of love.

Has Richard Rorty a moral philosophy?

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Mohammad Asghari

2015-06-01

Full Text Available I try to show that Richard Rorty, although is not a moral philosopher like Kant, nerveless, has moral philosophy that must be taken seriously. Rorty was not engaged with moral philosophy in the systematic manner common among leading modern and contemporary moral philosophers. This paper has two parts: first part, in brief, is concerned with principles of his philosophy such as anti-essentialism, Darwinism, Freudism, and historicism. Second part which be long and detailed, considers many moral themes in Rorty's thought such as critique of Kantian morality, solidarity, moral progress, cruelty and concept of other, etc. Subsequently, I will try to answer the research question of the article namely, has Rorty a moral philosophy?

Philosophy of biology. Is there still a need for philosophy?

Science.gov (United States)

Graziano, Mario

2013-01-01

In this paper we now focus on critically examining the theoretical and methodological conceptual foundations in the particular field of science of the living, namely the philosophy of biology. The latter seems to draw attention to two disparate disciplines in methods and scope of interest. On the one hand there seems to be a point of view that considers the cognitive phenomenon in question in a way so as to say "abstract", i.e. as something that seeks to determine the nature or essence, to use a term dear to many philosophers. On the other hand, there is a point of view that considers these phenomena in the actual place, the result of a process caused by the cognitive system of the subject, if the latter, of course, does not mean that they are human beings. We will argue that the two approaches do not represent two distinct planes of research: in fact philosophy takes on a main task, namely helping to lay the foundations for a philosophy of nature capable of meeting first a completeness, that is, to describe and explain what is special in all the different layers of the different natural systems.

Two Cheers for Naturalised Philosophy of Science--Or: Why Naturalised Philosophy of Science Is Not the Cat's Whiskers.

Science.gov (United States)

Worrall, John

1999-01-01

Argues that, although naturalized philosophy of science points to important aspects of the scientific process that have not attracted the attention they deserve, it is not an acceptable philosophy. Claims that the basic theses of full-fledged naturalized philosophy of science simply cannot be true since they end up either in logical circles or in…

Satellite Images and Aerial Photographs of the Effects of Hurricanes Katrina and Rita on Coastal Louisiana

Science.gov (United States)

Barras, John A.

2007-01-01

Introduction Hurricane Katrina made landfall on the eastern coastline of Louisiana on August 29, 2005; Hurricane Rita made landfall on the western coastline of Louisiana on September 24, 2005. Comparison of Landsat Thematic Mapper (TM) satellite imagery acquired before and after the landfalls of Katrina and Rita and classified to identify land and water demonstrated that water area increased by 217 mi2 (562 km2) in coastal Louisiana as a result of the storms. Approximately 82 mi2 (212 km2) of new water areas were in areas primarily impacted by Hurricane Katrina (Mississippi River Delta basin, Breton Sound basin, Pontchartrain basin, and Pearl River basin), whereas 99 mi2 (256 km2) were in areas primarily impacted by Hurricane Rita (Calcasieu/Sabine basin, Mermentau basin, Teche/Vermilion basin, Atchafalaya basin, and Terrebonne basin). Barataria basin contained new water areas caused by both hurricanes, resulting in some 18 mi2 (46.6 km2) of new water areas. The fresh marsh and intermediate marsh communities' land areas decreased by 122 mi2 (316 km2) and 90 mi2 (233.1 km2), respectively, and the brackish marsh and saline marsh communities' land areas decreased by 33 mi2 (85.5 km2) and 28 mi2 (72.5 km2), respectively. These new water areas represent land losses caused by direct removal of wetlands. They also indicate transitory changes in water area caused by remnant flooding, removal of aquatic vegetation, scouring of marsh vegetation, and water-level variation attributed to normal tidal and meteorological variation between satellite images. Permanent losses cannot be estimated until several growing seasons have passed and the transitory impacts of the hurricanes are minimized. The purpose of this study was to provide preliminary information on water area changes in coastal Louisiana acquired shortly after the landfalls of both hurricanes (detectable with Landsat TM imagery) and to serve as a regional baseline for monitoring posthurricane wetland recovery. The land

Philosophy in Seminaries

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Pawel Tarasiewicz

2013-12-01

Full Text Available The author attempts to answer the question concerning whether or not philosophy is needed in seminaries. In light of his analysis, it can be concluded that philosophical studies for future priests are a serious alternative to the fideistic positions often adopted by Catholics. The presence of philosophy in the seminary curriculum is supported by: (1 the need for building intellectual foundations of the religious faith professed by a cleric; the faith which cannot do without reason and abstain from justifying the rationale of its content; (2 the need for introducing the alumnus to the mysteries of the classical philosophy of being which can equip him with a better understanding of human nature and the surrounding reality. In this way, the seminarian: (1 acquires a reasonable belief that the human mind is able to know the objective and universal truth, including the truth about God as the Ultimate Cause of all that exists; (2 is able to enter into an intelligent dialogue about the truth with an increasingly globalized world.

A Confucian philosophy of medicine and some implications.

Science.gov (United States)

Lo, Ping-Cheung

2010-08-01

Two crucial topics in the philosophy of medicine are the philosophy of nature and philosophical anthropology. In this essay I engage the philosophy of nature by exploring Anne Fagot-Largeault's study of norms in nature as a way of articulating a Confucian philosophy of medicine. I defend the Confucian position as a moderate naturalism.

Continental Contributions to Philosophy of Science

OpenAIRE

REGINE KATHER

2006-01-01

The author reviews the book Continental Philosophy of Science, edited by Gary Gutting. Introductory remarks about the historical relationship between philosophy and science are followed by a presentation and discussion of different philosophies of science and commentaries on the eleven German and French authors whose texts are found in this volume. In addition to her assessment of Guttings’s collection, the author’s overall conclusion is that one characteristic trait of the Continental philos...

Philosophy 323, Readings in Asian Thought. Syllabus.

Science.gov (United States)

Hurdle, Burton G., Jr.

A survey course syllabus of Asian philosophy is presented. For each period of dates in the semester course, a reading assignment was made, discussion topics and questions proposed, and supplementary readings and sources suggested. The course focused on Indian philosophy, Buddhism and Hinduism, and Chinese philosophy, specifically Confucian…

Philosophy of Education and Other Educational Sciences

Science.gov (United States)

Howe, Kenneth R.

2014-01-01

This article largely agrees with John White's characterizations of the relationships among philosophy of education, philosophy more generally, and the conventional world. It then extends what White identifies as the fundamental problem that should now be occupying philosophy of education--the irreconcilable opposition between education for…

Performance and Philosophy Now

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Tasoula Kallenou

2015-11-01

Full Text Available Was Plato the first philosophical dramatist to explore philosophical ideas through dramatic content, introducing dramatic structures currently in line with contemporary theatre? If Plato was an influential figure for philosophers as well as theatre-makers, it can arguably be said that he was a silent pioneer in creating the newly defined discipline of Performance Philosophy. There is an obvious polarity between performance and philosophy since both disciplines are on the quest of exploring and presenting what life is. At least this can be said of ancient Greek and Roman philosophy. Conceived as “biou techne” the art of living, Greek and Roman philosophers, especially the Epicureans, Stoics and Skeptics, saw philosophy as a way of conceiving what a good life is (a life worth living and pursuing its practical realization for the attainment of eudemonia. Plato was arguably the first significant philosopher to explore philosophical ideas through dramatic content, introducing dramatic structures currently in line with contemporary theatre views. As such, he can be seen as an influential figure for theatre makers as well as for philosophers. Plato’s artistic intention was to uncover the artist that lacked substance and support the knowledgeable creative philosophical mind that besides instant emotional pleasure has to contribute in social development.

Applied philosophy and psychotherapy: Heraclitus as case study

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Johann Beukes

2002-10-01

Full Text Available This article investigates a recent attempt to apply philosophy within the discipline of psychotherapy and to investigate the somewhat undefined realm of philosophical counselling. After introducing the claims of this interdisciplinary exercise and after addressing the problems involved in crossing the boundaries between philosophy and psychotherapy, the article elaborates on  Alex Howard’s (2000 [Philosophy for counselling and psychotherapy: Pythagoras to post-modernism. London: Macmillan] attempt to make explicit use of philosophy in psychotherapy, using his interpretation and application of Heraclitus’ philosophy as case study.

Initial management of hospital evacuations caused by Hurricane Rita: a systematic investigation.

Science.gov (United States)

Downey, Erin L; Andress, Knox; Schultz, Carl H

2013-06-01

Hurricanes remain a major threat to hospitals throughout the world. The authors attempted to identify the planning areas that impact hospital management of evacuations and the challenges faced when sheltering-in-place. This observational, retrospective cohort study examined acute care institutions from one hospital system impacted by Hurricane Rita in 2005. Investigators used a standardized survey instrument and interview process, previously used in the hospital evacuation context, to examine hospitals' initial internal situational awareness and subsequent decision making that resulted in evacuation due to Hurricane Rita. Participants from each hospital included representatives from senior leadership and clinical and nonclinical staff that comprised the Incident Management Team (IMT). The main measured outcomes were responses to 95 questions contained in the survey. Seven of ten eligible hospitals participated in the study. All facilities evacuated the sickest patients first. The most significant factors prompting evacuation were the issuing of mandatory evacuation orders, storm dynamics (category, projected path, storm surge), and loss of regional communications. Hospitals that sheltered-in-place experienced staff shortages, interruptions to electrical power, and loss of water supplies. Three fully-evacuated institutions experienced understaffing of 40%-60%, and four hospitals sustained depressed staffing levels for over four weeks. Five hospitals lost electricity for a mean of 4.8 days (range .5-11 days). All facilities continued to receive patients to their Emergency Departments (EDs) while conducting their own evacuation. Hospital EDs should plan for continuous patient arrival during evacuation. Emergency Operation Plans (EOPs) that anticipate challenges associated with evacuation will help to maximize initial decision making and management during a crisis situation. Hospitals that shelter-in-place face critical shortages and must provide independent patient

Dyskusja dialogiczna – filozofia dzieciństwa i filozofia dorosłych [Dialogical discussion: philosophy of childhood and philosophy of adults

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Anna Łagodzka

2014-03-01

Full Text Available This article is devoted to the study of the educational approach based on Matthew Lipman’s Philosophy for Children. I examine its philosophical significance along with the concept of philosophy which underlies it and which is assumed in it. In ad- dition, I describe the model of inquiry which has been developed using this approach, giving it the name of dialogical discussion. Referring to Gareth B. Matthews, I use the two meanings of the term “philosophy of childhood” – philosophical reflection on childhood and philosophy created in childhood – in order to analyze the relationship between the philosophy of childhood and the philosophy of adults. I defend the thesis that inquiry, in which children explore the questions and insights made by children, is the practice of philosophy, not proto-philosophy or philosophy’s childhood. The opposite view I describe as didactical-philosophical paternalism, and it is consistent with the main prejudice which has dominated reflections on childhood so far. I situ- ate the role of the teacher within the perspective of the autonomy of the philosophy of childhood from the hitherto existing philosophical tradition, and also within the perspective of interactions between these two discourses. In the conclusion, I sketch out some possibilities for developing the discussed issues.

Mold exposure and health effects following hurricanes Katrina and Rita.

Science.gov (United States)

Barbeau, Deborah N; Grimsley, L Faye; White, LuAnn E; El-Dahr, Jane M; Lichtveld, Maureen

2010-01-01

The extensive flooding in the aftermath of Hurricanes Katrina and Rita created conditions ideal for indoor mold growth, raising concerns about the possible adverse health effects associated with indoor mold exposure. Studies evaluating the levels of indoor and outdoor molds in the months following the hurricanes found high levels of mold growth. Homes with greater flood damage, especially those with >3 feet of indoor flooding, demonstrated higher levels of mold growth compared with homes with little or no flooding. Water intrusion due to roof damage was also associated with mold growth. However, no increase in the occurrence of adverse health outcomes has been observed in published reports to date. This article considers reasons why studies of mold exposure after the hurricane do not show a greater health impact.

Philosophy and the Disciplines: The Borderlines | Minimah ...

African Journals Online (AJOL)

This work examines the borderlines of philosophy in relation to the central concern of other disciplines. As a preliminary step towards our examination, we attempt to uncover the specific nature of philosophy on the basis of its subject matter. We argue that while philosophy asks 'second order' questions about the totality of ...

Reflections concerning radiation protection philosophy

International Nuclear Information System (INIS)

Seelentag, W.

1981-01-01

Critical philosophy also includes observations of the technical amplified senses make, i.e. the application of accessory instruments, measuring instruments and statistic methods. The application of this philosophy is, among other things, referred to when taking the linear dose response relationship for stochastic radiation effects as an example. (DG) [de

Odera Oruka's Contribution to Philosophy

African Journals Online (AJOL)

Commentators on the four trends in contemporary African philosophy as enunciated by H. Odera Oruka frequently focus on the merits and demerits of each trend. However, many of them are obblivious to the way in which sagacity emancipates African philosophy by putting reason in its rightful pivotal position. This article ...

Philosophy across the Curriculum and the Question of Teacher Capacity; Or, What Is Philosophy and Who Can Teach It?

Science.gov (United States)

Bialystok, Lauren

2017-01-01

Pre-college philosophy has proliferated greatly over the last few decades, including in the form of "philosophy across the curriculum." However, there has been very little sustained examination of the nature of philosophy as a subject relative to other standard pre-college subjects and the kinds of expertise an effective philosophy…

Hurricane Rita and the destruction of Holly Beach, Louisiana: Why the chenier plain is vulnerable to storms

Science.gov (United States)

Sallenger, A.H.; Wright, C.W.; Doran, K.; Guy, K.; Morgan, K.

2009-01-01

Hurricane Rita devastated gulf-front communities along the western Louisiana coast in 2005. LIDAR (light detection and ranging) topographic surveys and aerial photography collected before and after the storm showed the loss of every structure within the community of Holly Beach. Average shoreline change along western Louisiana's 140-km-long impacted shore was -23.3 ?? 30.1 m of erosion, although shoreline change in Holly Beach was substantially less, and erosion was not pervasive where the structures were lost. Before the storm, peak elevations of the dunes, or berms in the absence of dunes, along the impacted shore averaged 1.6 m. The storm surge, which reached 3.5 m just east of Holly Beach, completely inundated the beach systems along the impacted western Louisiana shore. The high surge potential and low land elevations make this coast extremely vulnerable to hurricanes. In fact, most of the western Louisiana shore impacted by Rita will be completely inundated by the storm surge of a worst-case Saffi r-Simpson category 1 hurricane. All of this shore will be inundated by worst-case category 2-5 storms. ?? 2009 The Geological Society of America.

Freedom of Speech and Philosophy of Education

Science.gov (United States)

Harris, Roy

2009-01-01

Why is freedom of speech so seldom raised as an issue in philosophy of education? In assessing this question, it is important to distinguish (i) between a freedom and its exercise, and (ii) between different philosophies of education. Western philosophies of education may be broadly divided into classes derived from theories of knowledge first…

Kaupapa Maori, Philosophy and Schools

Science.gov (United States)

Stewart, Georgina

2014-01-01

Goals for adding philosophy to the school curriculum centre on the perceived need to improve the general quality of critical thinking found in society. School philosophy also provides a means for asking questions of value and purpose about curriculum content across and between subjects, and, furthermore, it affirms the capability of children to…

From Philosophy of History to Philosophy of Historicities: Some Ideas on a Potential Future of Historical Theory

Directory of Open Access Journals (Sweden)

Berber Bevernage

2012-12-01

Full Text Available Berber Bevernage does not share the pessimistic view that the philosophy of history is in crisis or coming to an end: it can have a bright and fascinating future. However in order to remain relevant, he argues, philosophy of history should look beyond academic historiography and transform into a broad ‘philosophy of historicities’ that also pays attention to the wide variety of extra-academic ways of dealing with the past. In order to do this current philosophy of history has to overcome a number challenges. First, it has to recognise that academic historiography did not develop in an intellectual vacuum but is closely related to particular social, cultural and political presuppositions about time and historicity on which it is partly dependent but which it can also reinforce or contradict. Second, it should recognise that different approaches to time and historicity have different social, cultural and political functions and not restrict its focus to philosophy of science or epistemological/cognitive issues. Third, it should focus on the ethics of history.

The Philosophy of Forestry

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Glenn W. Erickson

2010-10-01

Full Text Available Abstrac: In an extended discussion, within the context of a"philosophy offorestry", of the relationships of the concepts of truth and of tree some fundamental aspects of occidental metaphysics are examined from a Heideggerian perspective. But the paper tries to go beyond Heidegger's thematization of metaphysics in the context of pre-Socratic philosophy by establishing Indo-European etymology as a more inclusive horizon. In this manner, the transition from anti-metaphysics to post-metaphysics is anticipated.

Philosophy of medicine 2017: reviewing the situation.

Science.gov (United States)

Daly, Patrick

2017-12-01

In this introduction to a special subsection of Theoretical Medicine and Bioethics comprising separate reviews of the Springer Handbook of the Philosophy of Medicine, The Routledge Companion to Philosophy of Medicine, and The Bloomsbury Companion to Contemporary Philosophy of Medicine, I compare the three texts with respect to their overall organization and their approach to the relation between the science and the art of medicine. I then indicate two areas that merit more explicit attention in developing a comprehensive philosophy of medicine going forward: health economics and systematic relations within the field as a whole. The reviews that follow speak for themselves.

Present Day Philosophies of Education

Science.gov (United States)

Ediger, Marlow

2006-01-01

Presently, there are competing philosophies of education which need comparison. Two philosophies will be compared which are at opposite ends of the continuum. They are distinctly different. And yet, both schools of thought have their disciples. Each of the two will be discussed in terms of its essential features and then there will be selected…

Elementary School Philosophy: A Response

Science.gov (United States)

Wartenberg, Thomas E.

2012-01-01

This article is a response to criticism of my book "Big Ideas for Little Kids." The main topics addressed are: Who is the audience for the book? Can people without formal philosophical training can be good facilitators of elementary school philosophy discussions? Is it important to assess attempts to teach philosophy in elementary school? Should…

Review of the Philosophy of Intelligence

OpenAIRE

Gladwin, Lee A.

1993-01-01

A review of "The Philosophy of Artificial Intelligence, by Margaret A. Boden, ed., Oxford Readings in Philosophy, Oxford University Press, New York, New York, 1990, 460 pp., $14.95, ISBN 0-19-824854-7 (paper).

Object-oriented philosophy in designing adaptive finite-element package for 3D elliptic deferential equations

Science.gov (United States)

Zhengyong, R.; Jingtian, T.; Changsheng, L.; Xiao, X.

2007-12-01

Although adaptive finite-element (AFE) analysis is becoming more and more focused in scientific and engineering fields, its efficient implementations are remain to be a discussed problem as its more complex procedures. In this paper, we propose a clear C++ framework implementation to show the powerful properties of Object-oriented philosophy (OOP) in designing such complex adaptive procedure. In terms of the modal functions of OOP language, the whole adaptive system is divided into several separate parts such as the mesh generation or refinement, a-posterior error estimator, adaptive strategy and the final post processing. After proper designs are locally performed on these separate modals, a connected framework of adaptive procedure is formed finally. Based on the general elliptic deferential equation, little efforts should be added in the adaptive framework to do practical simulations. To show the preferable properties of OOP adaptive designing, two numerical examples are tested. The first one is the 3D direct current resistivity problem in which the powerful framework is efficiently shown as only little divisions are added. And then, in the second induced polarization£¨IP£©exploration case, new adaptive procedure is easily added which adequately shows the strong extendibility and re-usage of OOP language. Finally we believe based on the modal framework adaptive implementation by OOP methodology, more advanced adaptive analysis system will be available in future.

Modern Western Concepts of Philosophy of Education

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K. A. Ivanova

2017-08-01

Full Text Available The philosophy of education is represented by a wide range of concepts and approaches. The basic concepts of the philosophy of education can be divided into 4 groups according to the «pure» philosophical systems: realism, idealism, pragmatism, existentialism. Among the goals of the philosophy of education as an independent science are: stimulation, analysis, ordering, research. The delineation of the concept of education and the notion of school education are an important aspect in formulating the goals of the philosophy of education. A significant place in the process of finding and setting the goals of the philosophy of education is occupied by an alternative: discipline of mind or discipline of knowledge? It is worth paying attention to the goals of the modern Western philosophy of education: training for the formation of character, training for personal growth and success, training for the development and refinement of aesthetic predispositions, etc. Within the frameworks of the American philosophy of education, three main directions were formed: empiricism, rationalism, naturalism. According to the approach of the empiricists, education is the main factor, influencing human existence, which stimulates human activity, forms the person’s abilities and character. Rationalists introduced the idea of «self-alienation» as the most important for the philosophy of education. «Self-alienation» is a transition of a student from one stage of training to another one under the supervision of a teacher, when human mind becomes an object of his own attention. At the last stage of the student’s intellectual development, discovery of universals, laws and principles takes place. According to naturalists’ concept, the conclusions of scientific study of nature should be understood not as a testimony of truth, but as working hypotheses for further investigation. Scientific discoveries should be discoveries for education. Modern educational systems

Philosophy as Inquiry Aimed at the Absolute Knowledge

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Ekaterina Snarskaya

2017-09-01

Full Text Available Philosophy as the absolute knowledge has been studied from two different but closely related approaches: historical and logical. The first approach exposes four main stages in the history of European metaphysics that marked out types of “philosophical absolutism”: the evolution of philosophy brought to light metaphysics of being, method, morals and logic. All of them are associated with the names of Aristotle, Bacon/Descartes, Kant and Hegel. Then these forms are considered in the second approach that defined them as subject-matter of philosophy as such. Due to their overall, comprehensive character, the focus of philosophy on them justifies its claim on absoluteness as far as philosophy is aimed at comprehension of the world’s unity regardless of the philosopher’s background, values and other preferences. And that is its prerogative since no other form of consciousness lays down this kind of aim. Thus, philosophy is defined as an everlasting attempt to succeed in conceiving the world in all its multifold manifestations. This article is to try to clarify the claim of philosophy on the absolute knowledge.

A social philosophy of housing

OpenAIRE

King, Peter

2003-01-01

This book presents an original perspective by opening up housing to a philosophical approach. It fully integrates discussions on contemporary housing policy and social philosophy in a manner not previously attempted in the housing literature. Professor Jim Kemeny (Uppsala University) described it as ‘the first systematic application of social philosophy from an individual choice perspective’.

How philosophy of medicine has changed medical ethics.

Science.gov (United States)

Veatch, Robert M

2006-12-01

The celebration of thirty years of publication of The Journal of Medicine and Philosophy provides an opportunity to reflect on how medical ethics has evolved over that period. The reshaping of the field has occurred in no small part because of the impact of branches of philosophy other than ethics. These have included influences from Kantian theory of respect for persons, personal identity theory, philosophy of biology, linguistic analysis of the concepts of health and disease, personhood theory, epistemology, and political philosophy. More critically, medicine itself has begun to be reshaped. The most fundamental restructuring of medicine is currently occurring--stemming, in part, from the application of contemporary philosophy of science to the medical field. There is no journal more central to these critical events of the past three decades than The Journal of Medicine and Philosophy.

Inelastic neutron scattering experiments with the monochromatic imaging mode of the RITA-II spectrometer

International Nuclear Information System (INIS)

Bahl, C.R.H.; Lefmann, K.; Abrahamsen, A.B.; Ronnow, H.M.; Saxild, F.; Jensen, T.B.S.; Udby, L.; Andersen, N.H.; Christensen, N.B.; Jakobsen, H.S.; Larsen, T.; Haefliger, P.S.; Streule, S.; Niedermayer, Ch.

2006-01-01

Recently a monochromatic multiple data taking mode has been demonstrated for diffraction experiments using a RITA type cold neutron spectrometer with a multi-bladed analyser and a position-sensitive detector. Here, we show how this mode can be used in combination with a flexible radial collimator to perform real inelastic neutron scattering experiments. We present the results from inelastic powder, single crystal dispersion and single crystal constant energy mapping experiments. The advantages and complications of performing these experiments are discussed along with a comparison between the imaging mode and the traditional monochromatic focussing mode

Inelastic neutron scattering experiments with the monochromatic imaging mode of the RITA-II spectrometer

Energy Technology Data Exchange (ETDEWEB)

Bahl, C.R.H. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark) and Department of Physics, Technical University of Denmark, DK-2800 Lyngby (Denmark)]. E-mail: christian.bahl@risoe.dk; Lefmann, K. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark)]. E-mail: kim.lefmann@risoe.dk; Abrahamsen, A.B. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Ronnow, H.M. [Laboratory for Neutron Scattering, Paul Scherrer Institute, CH-5232 Villigen (Switzerland); Saxild, F. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Jensen, T.B.S. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Udby, L. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Andersen, N.H. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Christensen, N.B. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Laboratory for Neutron Scattering, Paul Scherrer Institute, CH-5232 Villigen (Switzerland); Jakobsen, H.S. [Niels Bohr Institute for Astronomy, Physics and Geophysics, University of Copenhagen, DK-2100 Copenhagen (Denmark); Larsen, T. [Niels Bohr Institute for Astronomy, Physics and Geophysics, University of Copenhagen, DK-2100 Copenhagen (Denmark); Haefliger, P.S. [Laboratory for Neutron Scattering, Paul Scherrer Institute, CH-5232 Villigen (Switzerland); Streule, S.; Niedermayer, Ch. [Laboratory for Neutron Scattering, Paul Scherrer Institute, CH-5232 Villigen (Switzerland)

2006-05-15

Recently a monochromatic multiple data taking mode has been demonstrated for diffraction experiments using a RITA type cold neutron spectrometer with a multi-bladed analyser and a position-sensitive detector. Here, we show how this mode can be used in combination with a flexible radial collimator to perform real inelastic neutron scattering experiments. We present the results from inelastic powder, single crystal dispersion and single crystal constant energy mapping experiments. The advantages and complications of performing these experiments are discussed along with a comparison between the imaging mode and the traditional monochromatic focussing mode.

Main physics features driving design concept and physics design constraints

International Nuclear Information System (INIS)

Fujisawa, Noboru; Sugihara, Masayoshi; Yamamoto, Shin

1987-07-01

Major physics design philosophies are described, which are essential bases for a plasma design and may have significant impacts on a reactor design concept. Those design philosophies are classified into two groups, physics design drivers and physics design constraints. The design drivers are featured by the fact that a designer is free to choose and the choice may be guided by his opinion, such as ignition, a pulse length, an operation scenario, etc.. The design constraints may follow a physical law, such as plasma confinement, β-limit, density limit, and so on. (author)

Pragmatism and Existential Philosophy

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Hans Lipps

2010-01-01

Full Text Available Hans Lipps compares pragmatism (William James and John Dewey existentialism (Friedrich Nietzsche, Soren Kierkegaard, and Martin Heidegger in this 1936 article translated from French.  He claims that they aim at the same goals, e.g., a return to lived experience and a rejection of the Cartesian legacy in philosophy.  While summarizing the commonalities of each, he engages in a polemic against philosophy then that remains relevant now into the next century.

Safety philosophy of the GTHTR300

International Nuclear Information System (INIS)

Kunitomi, Kazuhiko; Katanishi, Shoji

2003-01-01

In parallel to successful operation of the Japan's first High Temperature Gas-cooed Reactor, HTTR (High Temperature Engineering Test Reactor), JAERI (Japan Atomic Energy Research Institute) started design and development of a high temperature gas cooled reactor with a gas turbine electric generation system, GTHTR300 (Gas Turbine High Temperature Reactor 300), in April 2001. The GTHTR300 is expected to be deployed in 2010s as a safe and economically competitive electric generation system in Japan. Unique safety philosophy is proposed for this system. Severe accidents are defined as any conditions beyond design base accidents, causing core damages with fission product releases to the environment, although all severe accident sequences are very low in probability. The new safety philosophy is to avoid most accidents, and to achieve a probability of severe accidents of 10 -8 /ry that is at least two orders lower than current reactors. Even in the worst event such as double guillotine break of a primary concentric duct, fuel temperature exceeding its failure limit and excessive fuel oxidation by air ingress can be avoided because of inherent safety features and the passive decay heat removal system. Furthermore, double confinement buildings are enough to keep reactor safety in such accidents. Elimination of a leak-tight steel containment vessel is a big economical advantage for this system. Another unique feature is that nearly full-scale worst accident simulation tests can be carried out to obtain licensing before commercial operations because safety assessment by analysis is not usually enough to convince the public and the regulators of trusting this safety concept. In current reactors no accident simulation tests are carried out before commercial operations although inspection and performance tests in normal condition are conducted. This paper describes the safety philosophy together with the outline of the design features of the GTHTR300, and the results of

The Historical-Conceptual Language of Philosophy

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Fabián Mié

2009-08-01

Full Text Available In an essay devoted to the method of philosophy, Ernst Tugendhat (1989 warned about the scarcity of general methodological clarifications that this discipline offers for its own labor. Beyond the many ways there currently exist to make philosophy, and along its vast history, such lack of clarifications about the procedures can signal a lasting fault in the concept and scope of philosophy. Although Tugendhat is certainly right in his diagnosis, his proposal is quite incomplete and its formulation in the classical terms of the analytic tradition −according to which doing philosophy is a form of clarification in the use of linguistic expressions− must be completed with the historical feature which is peculiar to the discipline. However, in this paper I will not discuss this author’s thesis, but I will examine the methodological problem mapped out by him. The strategy is to start from what I consider a necessary previous step: to clarify the conceptual and historical dimensions of the philosophical vocabulary whereby this discipline handles its own topics. As a result, I will be able to derive some consequences vis-à-vis the method and goals of philosophy.

Mineral, Energy, and Fertilizer Resources of the North Coast of Peru: Perspective from the Santa Rita B Archaeological Site

Science.gov (United States)

Brooks, William E.; Kent, Jonathan D.; Willett, Jason C.

2004-01-01

The Santa Rita B archaeological site is in the Chao Valley, approximately 65 km southeast of Trujillo, northern Peru. Location of Santa Rita B at the emergence of several drainages from the Andean cordillera is an important factor in the almost continuous occupation of the site over the past 3,000 years. Mineral resources are abundant throughout the Andes; however, the north coast of Peru was an important center for pre-Columbian mining, metallurgy, and craftsmanship. Success of the Chavin, Moche, Chimu, and other north coast cultures is directly related to the availability and exploitation of mineral and energy resources that include: gold (?silver), as electrum, mainly from placers, and copper from local oxide and carbonate occurrences and from sulfides related to copper porphyry occurrences in the cordillera. An alloy of these three metals is referred to as tumbaga, which is the primary material for Andean metalcraft. Anthracite was used for mirrors by north coast cultures and is available near Rio Chicama, Rio Santa, and east of Santa Rita B. These outcrops are a part of the Alto Chicama, Peru's largest coalfield, which extends from Rio Chicama, in the north, for 200 km southward to Rio Santa. Charcoal from the algorrobo tree and llama dung are considered to be the common pre-Columbian energy sources for cooking and metalwork; however, availability and the higher heat content of anthracite indicate that it was used in metallurgical applications. Bitumen is available from petroleum seeps near Talara, north of the study area, and may have been used as glue or as cement. Hematite, goethite, limonite, and manganese oxides from clay-altered volcanic rock may have provided color and material for ceramics. Guano from the Islas Gua?apes, Chinchas, and Ballestas was used as fertilizer for cotton and other crops.

John Dewey on philosophy of experience and human education

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Darcísio Natal Muraro

2017-08-01

Full Text Available The objective of this study is to investigate the conception of philosophy and its relation to human formation in the thinking of John Dewey. The work aimed at analyzing the concepts in the main works of the author and his interpreters. The paper analyzes the reconstruction of philosophy as a philosophy of experience anchored in the genetic, experimental, reflexive, critical and creative method. The philosophy of experience is opposed to the dualisms and the spectator philosophies of knowledge that maintains the social division into classes. The role of the philosophy of experience is to rationalize through inquiry the possibilities of human experience through the critical reconstruction of the meanings. The philosophy of experience is a condition of possibility for democratic life and for an education based on freedom and human emancipation.

Mental Health, Substance Use, and Adaptive Coping among Social Work Students in the Aftermath of Hurricanes Katrina and Rita

Science.gov (United States)

Lemieux, Catherine M.; Plummer, Carol A.; Richardson, Roslyn; Simon, Cassandra E.; Ai, Amy L.

2010-01-01

The current study examined mental health symptomology, substance use, and adaptive coping among 416 social work students following Hurricanes Katrina and Rita. Among participants, 47% scored at or above the clinical level for depression, with 6% of students showing clinical PTSD-like symptoms, and 16.9% reporting substance use. Two thirds (66.9%)…

Environmental philosophy: from theory to practice.

Science.gov (United States)

Sarkar, Sahotra

2014-03-01

Environmental philosophy is a hybrid discipline drawing extensively from epistemology, ethics, and philosophy of science and analyzing disciplines such as conservation biology, restoration ecology, sustainability studies, and political ecology. The book being discussed both provides an overview of environmental philosophy and develops an anthropocentric framework for it. That framework treats natural values as deep cultural values. Tradeoffs between natural values are analyzed using decision theory to the extent possible, leaving many interesting question for philosophical deliberation. This framework is supposed to be applicable in practical contexts. Copyright © 2013 Elsevier Ltd. All rights reserved.

Problem-oriented approach to Ancient philosophy

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Berstov, Igor

2007-06-01

Full Text Available Igor Berestov and Marina Wolf of the Institute of philosophy and law, Novosibirsk, discuss various methodological difficulties typical of studies in the history of Ancient Greek philosophy and try to develop their own problem-oriented approach.

Philosophy versus Student Need? A Reply to Smith and Hilton.

Science.gov (United States)

Rainforth, Beverly

1994-01-01

This response to Smith and Hilton (1994) suggests that those authors reject philosophical bases for decision making regarding program design for students with mental retardation while actually proposing their own philosophical base for such decision making. The importance of philosophy in guiding decisions and practice over the last several…

Educational philosophy in China:a centennial retrospect and prospect

Institute of Scientific and Technical Information of China (English)

LU Youquan; CHI Yanjie

2007-01-01

Educational philosophy in China during the 20th century started with the introduction of John Dewey's educational philosophy thoughts,followed by the dissemination of Marxism thoughts of education,and initially established the framework of educational philosophy as an academic discipline.After the foundation of the People's Republic of China in 1949,especially during the 1980s,under the guidance of Marxism,the discipline of educational philosophy has been maturing.While exploring China's history of educational philosophy,this article also covers contemporary Western development.Future trends of this discipline include extending specific fields of research,increasing internationalization of research,enhancing the functions of both critique and guiding ideals of educational philosophy.

Stratigraphy of the Charqueadas Carboniferous basin, Santa Rita, RS, Brazil

Energy Technology Data Exchange (ETDEWEB)

Mendes Piccoli, A.E.; Holz, M.; Munaro, P.

1985-01-01

Sedimentological analyses of about 80 drill cores from the Charqueadas - Santa Rita Coal Field, west of Porto Alegre, Rio Grande do Sul State, were made. The Itarare Group is characterized by pelites of lacustrine origin and conglomerates and sandstones of alluvial fans, mainly in the north western region. A shallow lacustrine and paludal system characterize the Rio Bonito Formation, comprising coal seams and associated pelitic sediments, as well as some paraconglomerates and sandstone layers. The contact between these units is established by the colour of the pelites, differences in sedimentary textures, structures and palynological data. A marine transgression caused the sediments of the Rio Bonito Formation to be covered by coastal sandstones and pelites of the Palermo Formation, of tidal flat origin. Today, the coal layers and sediments have been eroded southward and slope gently to the north of the area.

Space Contestations and the Teaching of African Philosophy in ...

African Journals Online (AJOL)

... of focusing on Western philosophy 2) the fact that very few teachers of philosophy in Africa are focused mainly or only on Western philosophy in their academic productivity and 3) the disparity between the premises and the conclusion of the arguments in favour of the current pride of place accorded to Western philosophy.

'Whys' and 'Hows' of using philosophy in mathematics education

DEFF Research Database (Denmark)

Jankvist, Uffe Thomas; Iversen, Steffen Møllegaard

2014-01-01

The article elaborates and exemplifies a potential categorization of the reasons for using philosophy, in particular the philosophy of mathematics, in mathematics education and approaches to doing so—the so-called ‘whys’ and ‘hows’. More precisely, the ‘whys’ are divided into the two categories...... of ‘philosophy as a tool’ for teaching and learning mathematics, and ‘philosophy as a goal’, referring to a stance of considering it a purpose in itself to teach students certain aspects regarding the philosophy of mathematics. A division of the ‘hows’ into three different categories is offered: illumination...... approaches; modules approaches; and philosophy-based approaches. A major part of the article is spent on providing illustrative exemplifications of each of these approaches by referring to already implemented uses of philosophy of mathematics in mathematics education as well as by suggesting new ones....

Further Reflections on a Catholic Philosophy of Education

Science.gov (United States)

D'Souza, Mario O.

2018-01-01

Readers of this journal will recall two articles on the Catholic philosophy education: "Towards a contemporary Catholic philosophy of education," by Brendan Carmody SJ, [Carmody, Brendan. (2011). "Towards a Contemporary Catholic Philosophy of Education." "International Studies in Catholic Education" 3 (2): 106-119],…

Filosofia Theoretica: Journal of African Philosophy, Culture and ...

African Journals Online (AJOL)

Filosofia Theoretica Journal of African Philosophy, Culture and Religions, a publication of the Calabar School of Philosophy (CSP) is dedicated to the publication of astute academic research in African Philosophy, Culture, History, Art, Literature, Science, Education and Religions, etc. The articles submitted to Filosofia ...

[Philosophy of care, care and nursing care: a literature review for a research at the intersection of philosophy and care].

Science.gov (United States)

Remy-Largeau, Isabelle

2011-12-01

Very recently the concept of care has burst on the French philosophical scene. What are the contours of this developing "philosophy of care"? How does it place itself in relation to what are today called the ethics of care? And how does it take account of nursing care, as a discipline understood in its triple dimension: social, pedagogical and epistemological? The research presented in this paper examines some of the founding texts of this philosophy of care through the prism of these questions. It is the partial presentation of a reflection developed from a literature review that will include two other sections. The second section will focus on studying the way in which the ethics of care allow for nursing care and enter into dialogue with the nascent philosophy of care. The third will focus, conversely, on the way nurses integrate reflections derived from ethics of care and the philosophy of care into the evolution of their own discipline and contribute back to the development of a philosophy of care. These three questions are in turn part of more extensive research carried out in preparation for a philosophy thesis. They are meant as an invitation and a contribution towards what we hope will be a successful encounter between philosophy and nursing care.

Evidence of The Importance of Philosophy of Science Course On Undergraduate Level

Science.gov (United States)

Suyono

2018-01-01

This study aimed to describe academic impact of Philosophy of Science course in change of students’ conceptions on the Nature of science (NOS) before and after attending the course. This study followed one group pretest-posttest design. Treatment in this study was Philosophy of Science course for one semester. Misconception diagnostic tests of the NOS had been developed by Suyono et al. (2015) equipped with Certainty of Response Index (CRI). It consists of 15 concept questions about the NOS. The number of students who were tested on Chemistry Education Program (CEP) and Chemistry Program (CP) respectively 42 and 45 students. This study shows that after the learning of Philosophy of Science course happened: (1) the decrease of the number of misconception students on the NOS from 47.47 to 19.20% in CEP and from 47.47 to 18.18% in CP and (2) the decrease in the number of concepts that understood as misconception by the large number of students from 11 to 2 concepts on the CEP and from 10 to 2 concepts on CP. Therefore, the existence of Philosophy of Science course has a positive academic impact on students from both programs on undergraduate level.

Berkeley's Philosophy of Mathematics

CERN Document Server

Jesseph, Douglas M

1993-01-01

In this first modern, critical assessment of the place of mathematics in Berkeley's philosophy and Berkeley's place in the history of mathematics, Douglas M. Jesseph provides a bold reinterpretation of Berkeley's work. Jesseph challenges the prevailing view that Berkeley's mathematical writings are peripheral to his philosophy and argues that mathematics is in fact central to his thought, developing out of his critique of abstraction. Jesseph's argument situates Berkeley's ideas within the larger historical and intellectual context of the Scientific Revolution. Jesseph begins with Berkeley's r

Research philosophy in pharmacy practice: necessity and relevance.

Science.gov (United States)

Winit-Watjana, Win

2016-12-01

Pharmacy practice has gradually evolved with the paradigm shifted towards patient-focused practice or medicines optimisation. The advancement of pharmacy-related research has contributed to this progression, but the philosophy of research remained unexplored. This review was thus aimed to outline the succinct concept of research philosophy and its application in pharmacy practice research. Research philosophy has been introduced to offer an alternative way to think about problem-driven research that is normally conducted. To clarify the research philosophy, four research paradigms, i.e. positivism (or empiricism), postpositivism (or realism), interpretivism (or constructivism) and pragmatism, are investigated according to philosophical realms, i.e. ontology, epistemology, axiology and logic of inquiry. With the application of research philosophy, some examples of quantitative and qualitative research were elaborated along with the conventional research approach. Understanding research philosophy is crucial for pharmacy researchers and pharmacists, as it underpins the choice of methodology and data collection. The review provides the overview of research philosophy and its application in pharmacy practice research. Further discussion on this vital issue is warranted to help generate quality evidence for pharmacy practice. © 2016 Royal Pharmaceutical Society.

Reflections on the Growth and Development of Islamic Philosophy ...

African Journals Online (AJOL)

As a result of secular dimension that the Western philosophy inclines to, many see philosophy as a phenomenon that cannot be attributed to religion, which led to hasty conclusion in some quarters that philosophy is against religion and must be seen and treated as such. This paper looks at the concept of philosophy in ...

Rising Above the Water: New Orleans Implements Energy Efficiency and Sustainability Practices Following Hurricanes Katrina and Rita (Fact Sheet)

Energy Technology Data Exchange (ETDEWEB)

2012-07-01

This fact sheet describes the technical assistance that the U.S. Department of Energy, through its National Renewable Energy Laboratory, provided to New Orleans, Louisiana, which helped the city incorporate energy efficiency into its rebuilding efforts for K-12 schools and homes following Hurricanes Katrina and Rita. NREL also provided support and analysis on energy policy efforts.

An introduction to the philosophy of science

CERN Document Server

Staley, Kent W

2014-01-01

This book guides readers by gradual steps through the central concepts and debates in the philosophy of science. Using concrete examples from the history of science, Kent W. Staley shows how seemingly abstract philosophical issues are relevant to important aspects of scientific practice. Structured in two parts, the book first tackles the central concepts of the philosophy of science, such as the problem of induction, falsificationism, and underdetermination, and important figures and movements, such as the logical empiricists, Thomas Kuhn, and Paul Feyerabend. The second part turns to contemporary debates in the philosophy of science, such as scientific realism, explanation, the role of values in science, the different views of scientific inference, and probability. This broad yet detailed overview will give readers a strong grounding whilst also providing opportunities for further exploration. It will be of particular interest to students of philosophy, the philosophy of science, and science. Read more at h...

[The discourse of psychosis in contemporary philosophy].

Science.gov (United States)

Stompe, Thomas; Ritter, Kristina

2009-01-01

The preoccupation of philosophy with madness can be traced back till the Greek antiquity. For many philosophers like Descartes psychotic phenomena were symbols for the fragility of human mental powers, while others like Plato or Nietzsche saw madness as a way to escape the constraints of rationality. After 1960 three direction of contemporary philosophy dealt with the topics madness--schizophrenia--psychosis: Following Nietzsche and Bataille, Foucault as well as Deleuze and Guattari considered schizophrenia as the societal oppressed reverse of modern rationality, a notion which had a strong influence on the anti-psychiatric movement. Philosophical phenomenology primarily focussed on ontological problems of the psychotic existence. Finally Philosophy of Mind, the modern Anglo-American version of analytical philosophy, analyzed the logical coherence of psychotic inferences and experiences. Especially the insights of analytical philosophy may be important for a more sophisticated interpretation of psychopathological research as well as of the new findings of neuroscience.

GREEN CHEMISTRY: NEW CHEMICAL PHILOSOPHY

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F. A. Tykhomirova

2015-11-01

Full Text Available The review deals with the principles and guidelines of “Green chemistry” in comparison with the philosophy of nanotechnology. Modern philosophy and methodology of science research focus is on the process of the growth of scientific knowledge. Modern chemistry is complex, hierarchical, multilevel and multidimensional system. Philosophy of nanotechnology relies heavily on the value of scientism and the idea of domination of man over nature , there is an apology of human intervention in nature. “Green chemistry” is called “new thinking”of chemistry, philosophy of modern chemical research. The chemicals and processes in accordance with the principles of “Green chemistry” are considered not only in terms of production of substances and materials with desired properties, but also taking into account the consequences for the environment. In the “Green chemistry” created image of the “ideal customer” – he uses a minimum number of products understands the need to preserve the environment. Ideological landmark “Green chemistry” – co-evolution of man and nature, preservation of the biosphere. It emphasized the need to implement the ideology of “Green chemistry” in the training of future specialists.

The Method of Hypothesis in Plato's Philosophy

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Malihe Aboie Mehrizi

2016-09-01

Full Text Available The article deals with the examination of method of hypothesis in Plato's philosophy. This method, respectively, will be examined in three dialogues of Meno, Phaedon and Republic in which it is explicitly indicated. It will be shown the process of change of Plato’s attitude towards the position and usage of the method of hypothesis in his realm of philosophy. In Meno, considering the geometry, Plato attempts to introduce a method that can be used in the realm of philosophy. But, ultimately in Republic, Plato’s special attention to the method and its importance in the philosophical investigations, leads him to revise it. Here, finally Plato introduces the particular method of philosophy, i.e., the dialectic

CONTEMPORARY AFRICAN PHILOSOPHY, IDENTITY AND THE ...

African Journals Online (AJOL)

mycl

histories of African philosophy taking full consideration of Ancient. Egyptian philosophy ... philosophers there were thinkers who made deep philosophical reflections. ... for his conviction that independent critical sages existed in Africa who were .... against the African cannot but leave a strong negative impact on his psyche.

The Concept "System of Philosophy":The Case of Jacob Brucker's Historiography of Philosophy

OpenAIRE

Catana, Leo

2005-01-01

In this article I shall examine and discuss the concept ‘system of philosophy’ as a methodological tool in the history of philosophy. I shall do so in two moves. First I shall analyze the historical origin of the concept in the seventeenth and eighteenth centuries. Thereafter I shall undertake a discussion of its methodological weaknesses — a discussion, which is not only relevant to the writing of history of philosophy in the seventeenth and eighteenth centuries, but also to the writing of h...

The Role of History and Philosophy of in University Mathematics

DEFF Research Database (Denmark)

Kjeldsen, Tinne Hoff; Carter, Jessica M H Grund

2014-01-01

uses of history and the research direction in philosophy of mathematics denoted ‘Philosophy of Mathematical Practice’. We link history and philosophy of mathematical practices to recent ideas in mathematics education in order to identify different roles history and philosophy can play in the learning...... of mathematics at university level. We present, analyse and discuss different examples of inclusions of history and philosophy in university programmes in mathematics. These presentations are divided into courses in history and philosophy, respectively, since this is the main way they are organised...... at the universities. We shall see, however, that the history courses address philosophical questions and that the philosophy courses employ historical material. The chapter ends with comments on how mathematics educations at university level can benefit from history and philosophy of mathematics...

What Is Our First Philosophy in Mathematics Education?

Science.gov (United States)

Ernest, Paul

2012-01-01

What are the theoretical foundations of mathematics education? Recently disciplines other than mathematics and psychology have grown in importance, including philosophy. But which branch of philosophy is the most fundamental for mathematics education? In this article, I consider the claims of five branches of philosophy to be our "first…

The Relationship between Philosophy and Evidence in Education

Science.gov (United States)

Schouten, Gina; Brighouse, Harry

2015-01-01

This article explores the ways that philosophy and evidence interact in the exploration of normative questions in philosophy of education. First, the authors provide a description of reflective equilibrium, a central method in normative philosophizing. They proceed to describe three tasks of normative philosophy, each of which requires engagement…

The Philosophy of Self or Truth

OpenAIRE

Özgen, Mehmet Kasım

2015-01-01

What is meant by the ‘I’ is the philosophy that places the ‘I’ in the center and has a reflectional view on the ‘I’. This article deals with the differences between the philosophy of the ‘I’ in the West and the philosophy of the ‘Truth’ in the East. The person who approaches to the ‘I’ will also approaches to the ‘Truth’ or vice versa. In the modern point of view, modern ‘I’ is not innate. It is something man made, a result of human intention and decision and something invented. Individuals b...

Main engineering features driving design concept and engineering design constraints

International Nuclear Information System (INIS)

Saito, Ryusei; Kobayashi, Takeshi; Yamada, Masao

1987-09-01

Major engineering design philosophies are described, which are essential bases for an engineering design and may have significant impacts on a reactor design concept. Those design philosophies are classified into two groups, engineering design drivers and engineering design constraints. The design drivers are featured by the fact that a designer is free to choose and the choice may be guided by his opinion, such as coil system, a mechanical configuration, a tritium breeding scenario, etc.. The design constraints may follow a natural law or engineering limit, such as material strength, coil current density, and so on. (author)

Safety design

International Nuclear Information System (INIS)

Kunitomi, Kazuhiko; Shiozawa, Shusaku

2004-01-01

JAERI established the safety design philosophy of the HTTR based on that of current reactors such as LWR in Japan, considering inherent safety features of the HTTR. The strategy of defense in depth was implemented so that the safety engineering functions such as control of reactivity, removal of residual heat and confinement of fission products shall be well performed to ensure safety. However, unlike the LWR, the inherent design features of the high-temperature gas-cooled reactor (HTGR) enables the HTTR meet stringent regulatory criteria without much dependence on active safety systems. On the other hand, the safety in an accident typical to the HTGR such as the depressurization accident initiated by a primary pipe rupture shall be ensured. The safety design philosophy of the HTTR considers these unique features appropriately and is expected to be the basis for future Japanese HTGRs. This paper describes the safety design philosophy and safety evaluation procedure of the HTTR especially focusing on unique considerations to the HTTR. Also, experiences obtained from an HTTR safety review and R and D needs for establishing the safety philosophy for the future HTGRs are reported

Philosophy and Sociology Studies

Directory of Open Access Journals (Sweden)

S. A. Kravchenko

2014-01-01

Full Text Available Philosophy and Social science school of MGIMO has received both nationwide and international recognition. The traditions of the school were laid by two highly respected scientists and science managers, George P. Frantsev, who was the rector MGIMO during the crucial period of its early years, and Alexander F. Shishkin, who was the founder and head of the Department of Philosophy. The former belonged to one of the best schools of antic history studies of the Petersburg (Leningrad University. Frantsev made a great contribution to the restoration of Russian social and political science after World War II. After graduating from MGIMO, he worked at the Foreign Ministry of USSR, and then served as a rector of the Academy of Social Sciences and chief-editor of the journal "Problems of Peace and Socialism" in Prague. He consistently supported MGIMO scientists and recommended them as participants for international congresses and conferences. Shishkin was born in Vologda, and studied in Petrograd during 1920s. His research interests included history of education and morality. He was the author of the first textbook on ethics in the postwar USSR. Other works Shishkin, including monograph "XX century and the moral values of humanity", played a in reorienting national philosophy from class interests to universal moral principles. During thirty years of his leadership of the Department of Philosophy, Shishkin managed to prepare several generations of researchers and university professors. Scientists educated by Shishkin students consider themselves to be his "scientific grandchildren". The majority of MGIMO post-graduate students followed the footsteps of Frantsev in their research, but they also were guided by Shishkin's ideas on morality in human relations. Philosophy and Social science school of MGIMO played an important role in the revival of Soviet social and political science. Soviet Social Science Association (SSSA, established in 1958, elected Frantsev

UPANJE IN SVOBODA V DELU STEPHENA KINGA RITA HAYWORTH AND SHAWSHANK REDEMPTION IN ALEXANDRE DUMAS GROF MONTE CRISTO

OpenAIRE

Kramar, Vesna

2011-01-01

Rita Hayworth and Shawshank Redemption Stephena Kinga in Grof Monte Cristo Alexandra Dumasa izhajata iz različnih literarnih žanrov in se razlikujeta v dogajanju, a imata kljub temu podobno motiviko in tematiko. V obeh zgodbah je nedolžen mož poslan v zapor, iz katerega je pobeg skorajda nemogoč, a se kljub temu obema uspe izmuzniti iz zapora na podoben način

Moral Philosophy and Social Work Policy.

Science.gov (United States)

Reiman, Amanda

2009-10-01

Policies in the United States regarding personal responsibility and deviant behavior often follow an underlying moral philosophy. This paper examines the philosophies in American social policy, and how beliefs about personal responsibility, definitions of deviance and the role of the social welfare system shape current policies.

Moral Philosophy and Social Work Policy

OpenAIRE

Reiman, Amanda

2009-01-01

Policies in the United States regarding personal responsibility and deviant behavior often follow an underlying moral philosophy. This paper examines the philosophies in American social policy, and how beliefs about personal responsibility, definitions of deviance and the role of the social welfare system shape current policies.

Basic concepts of philosophy of management and corporations

DEFF Research Database (Denmark)

Rendtorff, Jacob Dahl

2013-01-01

This chapter presents some fundamental concepts of the philosophy of management and corporations by addressing the problem of corporate legitimacy and Immanuel Kant’s distinction between theoretical, practical, and aesthetic reason and judgment. This chapter begins with a general definition...... of philosophy of management and corporations and continues by presenting its ontological and epistemological underpinnings. This approach is used to address the relation between economics, business ethics, and philosophy of management. Finally, ethical and aesthetic judgment is presented as the mediator between...... theoretical, aesthetic, and practical reason in philosophy of management....

Philosophy and Ethics in Western Australian Secondary Schools

Science.gov (United States)

Millett, Stephan; Tapper, Alan

2014-01-01

The introduction of Philosophy and Ethics to the Western Australian Certificate of Education courses in 2008 brought philosophy into the Western Australian secondary school curriculum for the first time. How philosophy came to be included is part of a larger story about the commitment and perseverance of a relatively small number of Australian…

God, Sport Philosophy, Kinesiology: A MacIntyrean Examination

Science.gov (United States)

Twietmeyer, Gregg

2015-01-01

Sport philosophy is in crisis. This subdiscipline of kinesiology garners little to no respect and few tenure track lines in kinesiology departments. Why is this the case? Why isn't philosophy held in greater esteem? Is it possible that philosopher Alasdair MacIntyre's (2009) diagnosis found in "God, Philosophy, Universities" could…

Entrevista a María Rita Otero

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Olga Lucia Castiblanco Abril

2016-09-01

Full Text Available OC: Dra. María Rita, bienvenida a esta sección de la revista en donde siempre queremos que nuestros lectores conozcan personas de la vida académica en el campo de la investigación en Enseñeanza de las Ciencias. En primer lugar, nos gustaría que nos contara algo sobre su lugar actual como docente e invstigadora. MRO: Muchas gracias por la invitación. Quisiera contarles que hasta hace dos años fui profesora de secundaria durante 33 años. Actualmente soy profesora titular de la Universidad del Centro de la Provincia de Buenos Aires y soy investigadora principal del Consejo Nacional de Ciencia y tecnología de la República Argentina (Conicet. OC: ¿Cuál es su área de investigación? MRO: Estoy adscrita en el área de psicología y educación. Dentro de esta área trabajo en didáctica de las ciencias. Dirijo un equipo dentro de la universidad que se dedica a esto y a formar profesores de matemáticas, física e informática y también dirijo el doctorado.

African Tradition, Philosophy, and Modernization | Ikuenobe ...

African Journals Online (AJOL)

I examine Wiredu's views that (1) ethnophilosophy cannot be considered a legitimate philosophy because it has the feature of authoritarianism, and that (2) this feature of African tradition will not allow modern philosophy to flourish because it prevents individuals from rationally and critically examining beliefs. The ability to ...

Newton and scholastic philosophy.

Science.gov (United States)

Levitin, Dmitri

2016-03-01

This article examines Isaac Newton's engagement with scholastic natural philosophy. In doing so, it makes two major historiographical interventions. First of all, the recent claim that Newton's use of the concepts of analysis and synthesis was derived from the Aristotelian regressus tradition is challenged on the basis of bibliographical, palaeographical and intellectual evidence. Consequently, a new, contextual explanation is offered for Newton's use of these concepts. Second, it will be shown that some of Newton's most famous pronouncements - from the General Scholium appended to the second edition of the Principia (1713) and from elsewhere - are simply incomprehensible without an understanding of specific scholastic terminology and its later reception, and that this impacts in quite significant ways on how we understand Newton's natural philosophy more generally. Contrary to the recent historiographical near-consensus, Newton did not hold an elaborate metaphysics, and his seemingly 'metaphysical' statements were in fact anti-scholastic polemical salvoes. The whole investigation will permit us a brief reconsideration of the relationship between the self-proclaimed 'new' natural philosophy and its scholastic predecessors.

Philosophy in contemporary time: Relevance vs. Public perception ...

African Journals Online (AJOL)

What is the relevance of philosophy in this contemporary time? Philosophy is viewed by many people as an irrelevant discipline- one of no social and/or practical significance. It is sometimes seen also as an abstract and drab enterprise fit only for the intellectuals. Overtime also, philosophy has come to be perceived as ...

Feminisms and Challenges to Institutionalized Philosophy of Religion

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Nathan Eric Dickman

2018-04-01

Full Text Available For my invited contribution to this special issue of Religions on “Feminisms and the Study of ‘Religions,’” I focus on philosophy of religion and contestations over its relevance to the academic field of Religious Studies. I amplify some feminist philosophers’ voices—especially Pamela Sue Anderson—in corroboration with recent calls from Religious Studies scholars to diversify philosophy of religions in the direction of locating it properly within the current state of Religious Studies. I want to do this by thinking through two proposals in productive tension: first, any philosophy of religions worthy of the name is intrinsically feminist; second, any philosophy of religions worthy of the name is intrinsically traditional. I want to use the productive tension between these two to illuminate ways calls for broadening the field can be enhanced when such calls are seen as both feminist and traditional. I proceed as follows. First, I note three instances of explicitly feminist work in philosophy of religions that do not suffer from the same narrowness as so-called “traditional” philosophy of religion. Religious Studies critics of philosophy of religion overstate the case in claiming feminist philosophy of religion is too narrow. Second, I develop a useful distinction between the concepts of “tradition” and “institution” to locate forces of oppression more precisely in dynamics of institutionalization so that we might rehabilitate tradition as a resource for combating institutionalized oppressiveness. I do this in response to the hegemony of current philosophers of religion who claim to speak about “the traditional god.” And third, I briefly coordinate four topics in religions from diverse feminist perspectives to help refine paths of inquiry for future philosophy of religions that is both feminist and traditional. My hope is that these clarify a philosophy of religions renewed through feminisms—moving from fringe to

Transcendental Philosophy and its Transformations

DEFF Research Database (Denmark)

Ishihara, Yuko

There is an interesting overlap between Heidegger and Nishida that has not gained attention in the literature. During the late 1920s, both philosophers looked to transcendental philosophy as a way to overcome the Western metaphysical tradition. Neither philosopher, however,simply accepted...... traditional forms of transcendental philosophy. Rather, both attempted to transform it from within. In this work, I aim to articulate the extent to which Heidegger and Nishidastill worked within a traditional transcendental framework and also the ways in which they attempt to transform transcendental...... philosophy. I argue that while Heidegger’s “hermeneutic” and Nishida’s “chorological” (I employ this term from Plato’s chōra) transformations have much in common, the latter is more radical than the former. Specifically, Nishida reveals the pre-reflective origin of transcendental reflection not in the pre...

JPL Thermal Design Modeling Philosophy and NASA-STD-7009 Standard for Models and Simulations - A Case Study

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Avila, Arturo

2011-01-01

The Standard JPL thermal engineering practice prescribes worst-case methodologies for design. In this process, environmental and key uncertain thermal parameters (e.g., thermal blanket performance, interface conductance, optical properties) are stacked in a worst case fashion to yield the most hot- or cold-biased temperature. Thus, these simulations would represent the upper and lower bounds. This, effectively, represents JPL thermal design margin philosophy. Uncertainty in the margins and the absolute temperatures is usually estimated by sensitivity analyses and/or by comparing the worst-case results with "expected" results. Applicability of the analytical model for specific design purposes along with any temperature requirement violations are documented in peer and project design review material. In 2008, NASA released NASA-STD-7009, Standard for Models and Simulations. The scope of this standard covers the development and maintenance of models, the operation of simulations, the analysis of the results, training, recommended practices, the assessment of the Modeling and Simulation (M&S) credibility, and the reporting of the M&S results. The Mars Exploration Rover (MER) project thermal control system M&S activity was chosen as a case study determining whether JPL practice is in line with the standard and to identify areas of non-compliance. This paper summarizes the results and makes recommendations regarding the application of this standard to JPL thermal M&S practices.

Some Trends in the Philosophy of Physics

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Henrik Zinkernagel

2011-07-01

Full Text Available A short review of some recent developments in the philosophy of physics is presented. I focus on themes which illustrate relations and points of common interest between philosophy of physics and three of its `neighboring' elds: Physics, metaphysics and general philosophy of science. The main examples discussed in these three `border areas' are (i decoherence and the interpretation of quantum mechanics; (ii time in physics and metaphysics; and (iiimethodological issues surrounding the multiverse idea in modern cosmology.

Philosophy and mathematics: interactions.

Science.gov (United States)

Rashed, Roshdi

From Plato to the beginnings of the last century, mathematics provided philosophers with methods of exposition, procedures of demonstration, and instruments of analysis. The unprecedented development of mathematics on the one hand, and the mathematicians' appropriation of Logic from the philosophers on the other hand, have given rise to two problems with which the philosophers have to contend: (1) Is there still a place for the philosophy of mathematics? and (2) To what extent is a philosophy of mathematics still possible? This article offers some reflections on these questions, which have preoccupied a good many philosophers and continue to do so.

[Neurosciences and philosophy of mind].

Science.gov (United States)

Saal, Aarón

2005-01-01

In this paper we argue that the interaction between neurosciences and philosophy of the mind is on the way to understand consciousness, and to solve the mind-body or mind-brain problem. Naturalism is the view that mental processes are just brain processes and that consciousness is a natural phenomenon. It is possible to construct a theory about its nature by blending insights from neuroscience, philosophy of the mind, phenomenology, psychology and evolutionary biology.

Philosophy of a computer-automated counting system

International Nuclear Information System (INIS)

Perry, D.G.; Giesler, G.C.

1979-01-01

The LAMPF Nuclear Chemistry computer system is designed to provide both real-time control of data acquisition and facilities for data processing for a large variety of users. It is a PDP-11/34 connected to a parallel CAMAC branch highway as well as a large variety of peripherals. The philosophy for the design of this system is discussed; such points as use of the computer for control only versus direct data acquisition by the computer, why a CAMAC system was chosen, and the advantages and disadvantages of this system are covered. Also discussed are future expansion of the system and what might be done differently if the system were redesigned. 3 figures

La "fête mobile" de la non-philosophie

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Yvanka B. Raynova

2018-03-01

(Abstract   The editorial aims to unveil the attracting force of Laruelle's non-philosophy for scholars from different disciplines and artists. It shows how a new "democratic order of thinking" permits non-philosophy to enclose domains that have long been considered as opposites: philosophy, science, religion and the arts. Conceived as parameters of thought of the same right and without privileges, these variables can be superposed in a process of creative invention. The performative force of non-standard thinking, which can take different forms of philo-fiction, science fiction, art fiction, Christo-Fiction etc., dismantles the decisional gestures and the sufficiency claims of philosophy, science and religion, and thus permits a regeneration as well as a choral orchestration in a "minimalistic symphony". In this sense, non-philosophy invites us every day to the "movable feast", that it is.

Immanuel Kant, his philosophy and medicine.

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Wiesing, Urban

2008-06-01

The article examines the statements made by Immanuel Kant with reference to medicine as well as the impact of his philosophy on medicine. It describes the initial reaction of Kantian philosophy on medicine in the late 18th and early 19th century and its influence in the late 20th century.

Choosing phenomenology as a guiding philosophy for nursing research.

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Matua, Gerald Amandu

2015-03-01

To provide an overview of important methodological considerations that nurse researchers need to adhere to when choosing phenomenology as a guiding philosophy and research method. Phenomenology is a major philosophy and research method in the humanities, human sciences and arts disciplines with a central goal of describing people's experiences. However, many nurse researchers continue to grapple with methodological issues related to their choice of phenomenological method. The author conducted online and manual searches of relevant research books and electronic databases. Using an integrative method, peer-reviewed research and discussion papers published between January 1990 and December 2011 and listed in the CINAHL, Science Direct, PubMed and Google Scholar databases were reviewed. In addition, textbooks that addressed research methodologies such as phenomenology were used. Although phenomenology is widely used today to broaden understanding of human phenomena relevant to nursing practice, nurse researchers often fail to adhere to acceptable scientific and phenomenological standards. Cognisant of these challenges, researchers are expected to indicate in their work the focus of their investigations, designs, and approaches to collecting and analysing data. They are also expected to present their findings in an evocative and expressive manner. Choosing phenomenology requires researchers to understand it as a philosophy, including basic assumptions and tenets of phenomenology as a research method. This awareness enables researchers, especially novices, to make important methodological decisions, particularly those necessary to indicate the study's scientific rigour and phenomenological validity. This paper adds to the discussion of phenomenology as a guiding philosophy for nursing research. It aims to guide new researchers on important methodological decisions they need to make to safeguard their study's scientific rigour and phenomenological validity.

Feministische Philosophie in Zeiten des Post-Feminismus Feminist Philosophy in an Era of Post-Feminism

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Sidonia Blättler

2001-11-01

Full Text Available Herta Nagl-Docekal versucht im Durchgang durch verschiedene Teildisziplinen der Philosophie eine Zwischenbilanz: Wie hat feministisch motivierte Forschung das Fach verändert, und welche Fragen stehen heute zur Klärung an? Wie überzeugend ist die weit verbreitete These, wonach wir uns gegenwärtig in einer „postfeministischen“ Ära befinden und feministische Forschung obsolet geworden ist? Die von Herta Nagl-Docekal und Cornelia Klinger zusammengestellte Aufsatzsammlung enthält repräsentative Texte von deutschsprachigen Philosophinnen und soll ein englischsprachiges Publikum über hiesige Theorieentwicklungen innerhalb der feministischen Philosophie informieren.In her discussion of various sub-areas of philosophy Nagl-Docekal attempts a provisional survey of the state of the field: In what ways has feminist-motivated research changed the discipline of philosophy and what issues need to be addressed today? How relevant is the wide-spread idea that we are living in a “post-feminist” era and that feminist research has become obsolete? The other book is a reader, edited by Nagl-Docekal and Klinger, contains a number of representative essays of women philosophers from German-speaking countries. The editors intend to provide an English-speaking community about current developments in feminist theory in German-speaking countries.

Satellite Assessment of Bio-Optical Properties of Northern Gulf of Mexico Coastal Waters Following Hurricanes Katrina and Rita

OpenAIRE

Lohrenz, Steven E.; Cai, Wei-Jun; Chen, Xiaogang; Tuel, Merritt

2008-01-01

The impacts of major tropical storms events on coastal waters include sediment resuspension, intense water column mixing, and increased delivery of terrestrial materials into coastal waters. We examined satellite imagery acquired by the Moderate Resolution Imaging Spectroradiometer (MODIS) ocean color sensor aboard the Aqua spacecraft following two major hurricane events: Hurricane Katrina, which made landfall on 29 August 2005, and Hurricane Rita, which made landfall on 24 September. MODIS A...

Implications of the philosophy of Ch.S. Peirce for interdisciplinary design: developments in domain theory

NARCIS (Netherlands)

Bax, M.F.T.; Trum, H.M.G.J.; Nauta jr., D.; Timmermans, H.J.P.; Vries de, de B.

2000-01-01

Subject of this paper is the establishment of a connection between categorical pragmatism, developed by Charles Sanders Peirce (1839-1914) through phenomenological analysis, and Domain Theory, developed by Thijs Bax and Henk Trum since 1977. The first is a phenomenological branch of philosophy, the

Features of formation of philosophy of Russia

OpenAIRE

Baranov G. V.

2016-01-01

in article the main content of problems and achievements of philosophy of Russia on initial stage of its history is researched; urgent achievements of the Russian philosophy in their value for modern humanitarian culture are characterized.

School and the Limits of Philosophy

Science.gov (United States)

Fitzsimons, Peter

2014-01-01

Philosophy and schools, children and dynamite, elephants and postage stamps: each has a place, but not necessarily in any natural combination with the other. Whether schools and philosophy belong together depends largely on what we mean by both. To the extent that schools are instruments of government regulation and a mechanism for production of…

[Where is going philosophy of psychiatry ?].

Science.gov (United States)

Basso, Elisabetta

2016-12-01

This contribution provides a critical outline of the current trends in the field of "philosophy of psychiatry" by following their developments in the last decade. The first part of the paper focuses on the evolution of this field from a strictly conceptual approach to a perspective more attentive to the social, practical, and clinical dimension of psychiatry. The second part of the paper points out that the need of a mutual commitment of philosophy and psychiatry is perceived according to different ways by the countries involved in this research area. The paper deals especially with the case of France, where the enthusiasm for the "new philosophy of psychiatry" has not had the same impact on the philosophical scene as in the English speaking countries. In conclusion, the paper shows that the field of philosophy of psychiatry stands as a fertile ground for new forms of interaction between the analytic, and the continental philosophical traditions. This interaction takes place, more particularly, as regards such topics as normativity, language, and interpretation.

Logic and philosophy of mathematics in the early Husserl

CERN Document Server

Centrone, Stefania

2010-01-01

This text focuses on the first ten years of Edmund Husserl's work, from the publication of his Philosophy of Arithmetic to that of Logical Investigations. It aims to locate this work in the fields of logic, philosophy of logic and philosophy of mathematics.

A Philosophy Research Database to Share Data Resources

Directory of Open Access Journals (Sweden)

Jili Cheng

2007-12-01

Full Text Available Philosophy research used to rely mainly on the traditional published journals and newspapers for collecting or communicating data. However, because of financial limits or lack of capability to collect data, required published materials and even restricted materials and developing information from research projects often could not be obtained. The rise of digital techniques and Internet opportunities has allowed data resource sharing of philosophy research. However, although there are several ICPs with large-scale comprehensive commercial databases in the field in China, no real non-profit professional database for philosophy researchers exists. Therefore, in 2002, the Philosophy Institute of the Chinese Academy of Social Sciences began a project to build "The Database of Philosophy Research." Until Mar. 2006 the number of subsets had reached 30, with more than 30,000 records, retrieval services reached 6,000, and article-reading reached 30,000. Because of the concept of intellectual property, the service of the database is currently limited to the information held in CASS. Nevertheless, this is the first academic database for philosophy research, so its orientation is towards resource-sharing, leading users to data, and serving large number of demands from other provinces and departments.

Rita Pawlowski (Hg.: „Unsere Frauen stehen ihren Mann“. Berlin: trafo Wissenschaftsverlag 2008

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Susanne Freund

2009-07-01

Full Text Available Rita Pawlowski stellt in diesem Band in alphabethischer Ordnung insgesamt 651 Frauen vor, die Abgeordnete der Volkskammer der DDR waren. Nach einer knappen Einführung zur Wahlhäufigkeit weiblicher Abgeordneter, zum Frauenanteil in der Volkskammer und in den Ausschüssen geben die Biographen im Wesentlichen Auskunft über die soziale Herkunft, die Parteizugehörigkeit, die schulische und berufliche Ausbildung und die Berufstätigkeit der einzelnen Frauen. Ziel dieses Bandes ist die Dokumentation des außergewöhnlichen Engagements von Frauen in der DDR, neben Berufstätigkeit und Familienpflichten politische Einflussmöglichkeiten zu nutzen. Damit wird ein Teilaspekt der Lebensgeschichte dieser Frauen beleuchtet, der – wie die Autorin im Vorfeld einräumt – keinen Anspruch auf Vollständigkeit erhebt. Dieser Hinweis ist wichtig, um dieses lexikalische Nachschlagewerk sinnvoll zu handhaben.In this volume, Rita Pawlowski alphabetically introduces a total of 651 women who were representatives of the People’s Chamber of the GDR. Following a short introduction to the election frequency of female representatives and to the number of women in the People’s Chamber and its committees, the biographies provide information on the social origin, party membership, educational and occupational training, and professional life of the individual women. The volume’s goal is to document these women’s extraordinary engagement in the GDR, for they not only held careers and fulfilled family duties, but also pursued possibilities for making political impact. The authors note at the outset that the book does not claim to be comprehensive, for it illuminates merely one aspect of the life stories of these women. This remark is important for making the reference work manageable.

A unifying philosophy of governance

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Sankarshan Acharya

2012-09-01

Full Text Available Bertrand Russell won Nobel Prize for arguing that science has triumphed over religion. Since religions are based on god, Russell’s argument implies that science has triumphed over both religion and god. But neither Russell nor anyone else has ever defined religion and god, rationally. The assertion about triumph of science (which is founded on rationality over concepts such as religion and god (which are not defined rationally or scientifically in the extant literature cannot be rational. This paper offers a novel rational philosophical foundation for the concepts of god, religion and science in which the claim that science triumphs over religion is redundant. This paper also presents substantial new insights about epistemic truths to help resolve current problems facing humanity like financial moral hazard and terrorism which have unnerved nations worldwide. The humanity now begs to answer a fundamental question of how we can govern ourselves. This paper offers a coherent set of credible answers. In particular, it offers a coherent unified philosophy about how humans have universally formed beliefs to govern themselves and how this philosophy could help resolve current problems. The universal rendering of beliefs articulated here subsumes the extant characterization of probability beliefs in mathematics, science, engineering, economics, religion and philosophy. The universal beliefs so articulated in this paper obviate the currently prevalent philosophical conflicts between religion and science or between theism and atheism and paves the way for optimal governance for prosperity amid stability. This philosophy also offers a rational characterization of the spiritual notion of Nirvana or salvation of the soul and the notion of epistemic truth. The unifying philosophy can help humanity achieve unity, stability and prosperity, sans financial moral hazard, antagonism, wars, nuclear proliferation, global warming and atmospheric pollution.

Challenging the Conventional Wisdom: From Philosophy to Bioethics.

Science.gov (United States)

Miller, Franklin G

2017-01-01

Philosophy is a core discipline that has contributed importantly to bioethics. In this essay, the author traces his trajectory from philosophy to bioethics, oriented around the theme of challenging the conventional wisdom. Three topics are discussed to illustrate this theme: the ethics of randomized trials, determination of death and organ transplantation, and pragmatism as a method of bioethics. In addition, the author offers some general reflections on the relationship between philosophy and bioethics. Philosophy recovers itself when it ceases to be a device for dealing with the problems of philosophers and becomes a method, cultivated by philosophers, for dealing with the problems of men.-John Dewey (1917).

Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu

Directory of Open Access Journals (Sweden)

Luan Jinwei

2016-06-01

Full Text Available Next generation sequencing and bio-informatic analyses were conducted to investigate the mechanism of reactivation of p53 and induction of tumor cell apoptosis (RITA-enhancing X-ray susceptibility in FaDu cells.

Philosophy of Money

CERN Document Server

Simmel, Georg; Frisby, David; Bottomore, Tom

2011-01-01

In The Philosophy of Money, Georg Simmel provides us with a now classic discussion of the social, psychological and philosophical aspects of the money economy, full of brilliant insights into the forms that social relationships take.

Wherefore Art Thou Philosophy? Badiou without Badiou

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Jason Barker

2012-05-01

Full Text Available Given the encroaching, seemingly pernicious backlash against Alain Badiou’s thinking, which appears partly motivated by the bad faith of “philosophical” rivalries, this essay aims to argue in favour of the ongoing and authentically philosophical stakes of Badiou’s ontology. At the same time the essay attempts to highlight the methodological difficulties Badiou encounters in attempting to reconcile an intrinsic ontology as the dominant condition of philosophy, with a philosophy of the event. The essay concludes by speculating on the “unbound”, “unconditioned” potential of this two-headed philosophy.

Philosophy for the rest of cognitive science.

Science.gov (United States)

Stepp, Nigel; Chemero, Anthony; Turvey, Michael T

2011-04-01

Cognitive science has always included multiple methodologies and theoretical commitments. The philosophy of cognitive science should embrace, or at least acknowledge, this diversity. Bechtel's (2009a) proposed philosophy of cognitive science, however, applies only to representationalist and mechanist cognitive science, ignoring the substantial minority of dynamically oriented cognitive scientists. As an example of nonrepresentational, dynamical cognitive science, we describe strong anticipation as a model for circadian systems (Stepp & Turvey, 2009). We then propose a philosophy of science appropriate to nonrepresentational, dynamical cognitive science. Copyright © 2011 Cognitive Science Society, Inc.

Physics, philosophy and environment

International Nuclear Information System (INIS)

Angel Maya, Augusto

2001-01-01

Physics and philosophy has join developments since the Jonios. The present article tries to analyze some of the philosophical problems that arise of the classic and contemporary physics and that affect the environmental vision. In general, it can be said that the discoveries of the physics has meant a progressive desplatonization of the western world, including the remaining of Platon that is included in Aristoteles philosophy. From the analysis some problems arise that is worthwhile to emphasize. Above all the relationship between determinism and random theory, from the environmental perspective it is necessary to wonder if it is licit to apply these concepts to man. With it the problem of freedom arise, attacked by Spinoza, but carefully protected by Kant's philosophy. Their acceptance supposes, however, the division between man and the cultural schizophrenia. Is it possible to explain freedom from the physics, such as was pretended by Epicuro or Prigonine? Has nature a wide field of freedom as it is assumed in some of the currents of contemporary physics? All of them are questions that the environmental thought has to confront, although it cannot solve them

Rita Temmerman. Towards New Ways of Terminology Description: The Sociocognitive Approach

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Rosemarie Gläser

2011-10-01

Full Text Available This book appeared as Volume 3 in the Series Terminology and Lexicography Research and Practice edited by Helmi Sonneveld and Sue-Ellen Wright. The author, Rita Temmerman, presently working at the Erasmus Hogeschool, Brussels and specialising in problems of terminology in various domains of the life sciences, presents a polemical, stimulating and innovative monograph which continues and deepens her previous research work. Her doctoral dissertation (Louvain 1998 focused on Terminology Beyond Standardisation: Language and Categorisation in the Life Sciences. The aim of the book under review, Towards New Ways of Terminology Description: The Sociocognitive Approach, is to elaborate a new theory, method and application of terminology research which seeks to overcome the obvious limitations of traditional terminology as chiefly represented by the Vienna School (Eugen W?ster, Helmut Felber, Infoterm and associated institutions.

Monitoring Inland Storm Surge and Flooding from Hurricane Rita

Science.gov (United States)

McGee, Benton D.; Tollett, Roland W.; Mason, Jr., Robert R.

2006-01-01

Pressure transducers (sensors) and high-water marks were used to document the inland water levels related to storm surge generated by Hurricane Rita in southwestern Louisiana and southeastern Texas. On September 22-23, 2005, an experimental monitoring network of sensors was deployed at 33 sites over an area of about 4,000 square miles to record the timing, extent, and magnitude of inland hurricane storm surge and coastal flooding. Sensors were programmed to record date and time, temperature, and barometric or water pressure. Water pressure was corrected for changes in barometric pressure and salinity. Elevation surveys using global-positioning systems and differential levels were used to relate all storm-surge water-level data, reference marks, benchmarks, sensor measuring points, and high-water marks to the North American Vertical Datum of 1988 (NAVD 88). The resulting data indicated that storm-surge water levels over 14 feet above NAVD 88 occurred at three locations, and rates of water-level rise greater than 5 feet per hour occurred at three locations near the Louisiana coast.

Os Episódios de Rita Patrício

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Gustavo Rubim

2014-12-01

O texto propõe uma leitura do livro Episódios: da teorização estética em Fernando Pessoa, da au­toria de Rita Patrício. Datado de 2012, o livro só ficou realmente pronto e publicado em 2014. A leitura de­fende a originalidade deste exame minucioso dos textos de teoria estética e literária de Fernando Pessoa, tanto pela maneira como os trata autonomamente da obra poética e os estuda na sua escrita específica, quanto pelo efeito de deslocação dos tópicos habituais na análise do programa modernista português. A crí­tica do idealismo pessoano e da noção de obra enquanto totalidade or­gânica são sublinhados enquanto gestos condutores de toda a pesquisa. Propõem-se articulações com outros ensaios recentes que em Portugal procedem à revisão da crítica e da hermenêutica pes­soana.

RITA--Registry of Industrial Toxicology Animal data: the application of historical control data for Leydig cell tumors in rats.

Science.gov (United States)

Nolte, Thomas; Rittinghausen, Susanne; Kellner, Rupert; Karbe, Eberhard; Kittel, Birgit; Rinke, Matthias; Deschl, Ulrich

2011-11-01

Historical data for Leydig cell tumors from untreated or vehicle treated rats from carcinogenicity studies collected in the RITA database are presented. Examples are given for analyses of these data for dependency on variables considered to be of possible influence on the spontaneous incidence of Leydig cell tumors. In the 7453 male rats available for analysis, only one case of a Leydig cell carcinoma was identified. The incidence of Leydig cell adenomas differed markedly between strains. High incidences of close to 100% have been found in F344 rats, while the mean incidence was 4.2% in Sprague-Dawley rats and 13.7% in Wistar rats. Incidences in Wistar rats were highly variable, primarily caused by different sources of animals. Mean incidences per breeder varied from 2.8 to 39.9%. Analyses for the dependency on further parameters have been performed in Wistar rats. In breeders G and I, the Leydig cell tumor incidence decreased over the observation period and with increasing mean terminal body weight. The incidence of Leydig cell tumors increased with mean age at necropsy and was higher in studies with dietary admixture compared to gavage studies. These parameters had no effect on Leydig cell tumor incidence in breeders A and B. Animals from almost all breeders had a considerably higher mean age at necropsy when bearing a Leydig cell adenoma than animals without a Leydig cell adenoma. Studies with longitudinal trimming of the testes had a higher incidence than studies with transverse trimming. The observed dependencies and breeder differences are discussed and explanations are given. Consequences for the use of historical control data are outlined. With the retrospective analyses presented here we were able to confirm the published features of Leydig cell adenomas and carcinomas. This indicates that the RITA database is a valuable tool for analyses of tumors for their biological features. Furthermore, it demonstrates that the RITA database is highly beneficial for

Taipower's philosophy and practices for management of its nuclear power development program

International Nuclear Information System (INIS)

Chu, D.S.L.

1985-01-01

Taipower has been considered successful in nuclear power development and utilization in recent years. This paper presents Taipower's philosophy and practices in managing its nuclear power program with respect to management participation, personnel training, planning, design and construction, operation and maintenance, and the fuel cycle

Multi-proxy Characterization of Two Recent Storm Deposits Attributed to Hurricanes Rita and Ike in the Chenier Plain of Southwestern Louisiana

Science.gov (United States)

Yao, Q.; Liu, K. B.; Ryu, J.

2017-12-01

The Chenier Plain in southwestern Louisiana owes its origin to dynamic depositional processes that are dominated by delta-switching of the Mississippi River to the east, while frequent hurricane activities also play an important role in its geomorphology and sedimentary history. However, despite several studies in the literature, the sediment-stratigraphic characteristics of recent or historic hurricane deposits are still not well documented from the Chenier Plain. In 2005 and 2008, Hurricane Rita (category 3) and Ike (category 2) made landfall on the coasts of Louisiana and Texas. Remote sensing images confirm that the Rockefeller Wildlife Refuge, located at the east end of the Louisiana Chenier Plain, was heavily impacted by both hurricanes. We analyzed the lithology and chemical stratigraphy of three 30 cm sediment monoliths (ROC-1, ROC-2, and ROC-3) recovered from a coastal saltmarsh in the Rockefeller Wildlife Refuge to identify the event deposits attributed to these two storms. Each monolith contains 2 distinct light-colored clastic sediment layers imbedded in brown organic clay. The loss-on-ignition and X-ray fluorescence results show that the hurricane layers have increased contents of Ca, Sr, Zr, and carbonates and decreased contents of water and organics. Surprisingly, despite its greater intensity and more severe impacts, Hurricane Rita left a much thinner storm deposit than did Hurricane Ike in all monoliths. Satellite data reveal that Hurricane Rita caused significant coastal erosion and shoreline recession, rendering the sampling sites much closer to the beach and ocean and therefore more prone to storm surges and overwash deposition than when Hurricane Ike struck three years later. Our results suggest that site-to-sea distance, which affects a study site's paleotempestological sensitivity, can play a bigger role in affecting the thicknesses of storm deposits than the intensity of the hurricane.

Safety philosophy in Plowshare

Energy Technology Data Exchange (ETDEWEB)

Thalgott, R H [Nevada Operations Office, U.S. Atomic Energy Commission (United States)

1969-07-01

A nuclear device can be detonated safely when it can ascertained that the detonation can be accomplished without injury to people, either directly or indirectly, and without unacceptable damage to the ecological system and natural or man made structures. This philosophy has its origin in the nuclear weapons testing program dating back to the first detonation in 1945 and applies without reservation to PIowshare projects. This paper therefore will outline the mechanics employed by government in implementing this safety philosophy. The talk will describe those type of actions taken by safety oriented organizations and committees to assure that necessary and desirable safety reviews are conducted. (author)

Safety philosophy in Plowshare

International Nuclear Information System (INIS)

Thalgott, R.H.

1969-01-01

A nuclear device can be detonated safely when it can ascertained that the detonation can be accomplished without injury to people, either directly or indirectly, and without unacceptable damage to the ecological system and natural or man made structures. This philosophy has its origin in the nuclear weapons testing program dating back to the first detonation in 1945 and applies without reservation to PIowshare projects. This paper therefore will outline the mechanics employed by government in implementing this safety philosophy. The talk will describe those type of actions taken by safety oriented organizations and committees to assure that necessary and desirable safety reviews are conducted. (author)

"Whys" and "Hows" of Using Philosophy in Mathematics Education

Science.gov (United States)

Jankvist, Uffe Thomas; Iversen, Steffen Møllegaard

2014-01-01

The article elaborates and exemplifies a potential categorization of the reasons for using philosophy, in particular the philosophy of mathematics, in mathematics education and approaches to doing so-the so-called "whys" and "hows". More precisely, the "whys" are divided into the two categories of "philosophy as…

Group Design Problems in Engineering Design Graphics.

Science.gov (United States)

Kelley, David

2001-01-01

Describes group design techniques used within the engineering design graphics sequence at Western Washington University. Engineering and design philosophies such as concurrent engineering place an emphasis on group collaboration for the solving of design problems. (Author/DDR)

Radiation protection philosophy: time for changes?

International Nuclear Information System (INIS)

Jovanovich, J.V.

1994-01-01

Radiation protection philosophy, or paradigm, has evolved over a number of decades and it is still evolving. Traditionally, it has dealt only with man-made, planned, in principle avoidable, radiation exposures of workers and general public. This philosophy, as presently accepted around the world, has some deficiencies. The object of this paper is to discuss these deficiencies and propose some changes. (author)

Eye of the storm: analysis of shelter treatment records of evacuees to Acadiana from Hurricanes Katrina and Rita.

Science.gov (United States)

Caillouet, L Philip; Paul, P Joseph; Sabatier, Steven M; Caillouet, Kevin A

2012-01-01

specific evaluation and care, no population-based experimental hypothesis was framed nor was the effectiveness of any specific intervention researched at the time. This study reports experiential data collected without a particular preconceived hypothesis, because no specific outcome measures had been designed in advance. Data analysis revealed much about the origins and demographics of the evacuees, their hurricane-related risks and injuries, and the loss of continuity in their prior and ongoing healthcare. The authors believe that much can be learned from studying data collected in evacuee triage clinics, and that such insights may influence personal and official preparedness for future events. In the Katrina-Rita evacuations, only paper-based data collection mechanisms were used-and those with great inconsistency-and there was no predeployed mechanism for close-to-real-time collation of evacuee data. Deployment of simple electronic health record systems might well have allowed for a better real-time understanding of the unfolding of events, upon arrival of evacuees in shelters. Information and communication technologies have advanced since 2005, but predisaster staging and training on such technologies is still lacking.

"Inside-out Pedagogy": Theorising Pedagogical Transformation through Teaching Philosophy

Science.gov (United States)

Scholl, Rosie

2014-01-01

This retrospective interview study focused on the impact that training and implementation of Philosophy, in Lipman's tradition of Philosophy for Children, had on the pedagogy of 14 primary teachers at one school. Semi-structured interviews were conducted to document the impact of teaching Philosophy on pedagogy, the resources required to…

Educational Philosophy in China: A Centennial Retrospect and Prospect

Science.gov (United States)

Lu, Youquan; Chi, Yanjie

2007-01-01

Educational philosophy in China during the 20th century started with the introduction of John Dewey's educational philosophy thoughts, followed by the dissemination of Marxism thoughts of education, and initially established the framework of educational philosophy as an academic discipline. After the foundation of the People's Republic of China in…

On the way to a philosophy of science education

Science.gov (United States)

Schulz, Roland M.

This Thesis argues the case that a philosophy of science education is required for improving science education as a research field as well as curriculum and teacher pedagogy. It seeks to re-think science education as an educational endeavor by examining why past reform efforts have been only partially successful, including why the fundamental goal of achieving scientific literacy after several "reform waves" has proven to be so elusive. The identity of such a philosophy is first defined in relation to the fields of philosophy, philosophy of science, and philosophy of education. Considering science education as a research discipline it is emphasized a new field should be broached with the express purpose of developing a discipline-specific "philosophy of science education" (largely neglected since Dewey). A conceptual shift towards the philosophy of education. is needed, thereto, on developing and demarcating true educational theories which could in addition serve to reinforce science education's growing sense of academic autonomy and independence from socio-economic demands. Two educational metatheories are contrasted, those of Kieran Egan and the Northern European Bildung tradition, to illustrate the task of such a philosophy. Egan's cultural-linguistic metatheory is presented for two primary purposes: it is offered as a possible solution to the deadlock of the science literacy conceptions within the discipline; regarding practice, examples are provided how it can better guide the instructional practice of teachers, specifically how it reinforces the work of other researchers in the History and Philosophy of Science (HPS) reform movement who value narrative in learning science. Considering curriculum and instruction, a philosophy of science education is conceptualized as a "second order" reflective capacity of the teacher. This notion is aligned with Shulman's idea of Pedagogical Content Knowledge. It is argued that for educators the nature of science learning

On the emergence of American analytic philosophy

NARCIS (Netherlands)

Katzav, J.; Vaesen, K.

2017-01-01

This paper is concerned with the reasons for the emergence and dominance of analytic philosophy in America. It closely examines the contents of, and changing editors at, The Philosophical Review, and provides a perspective on the contents of other leading philosophy journals. It suggests that

Advanced power generation systems for the 21st Century: Market survey and recommendations for a design philosophy

Energy Technology Data Exchange (ETDEWEB)

Andriulli, J.B.; Gates, A.E.; Haynes, H.D.; Klett, L.B.; Matthews, S.N.; Nawrocki, E.A.; Otaduy, P.J.; Scudiere, M.B.; Theiss, T.J.; Thomas, J.F.; Tolbert, L.M.; Yauss, M.L.; Voltz, C.A.

1999-11-01

The purpose of this report is to document the results of a study designed to enhance the performance of future military generator sets (gen-sets) in the medium power range. The study includes a market survey of the state of the art in several key component areas and recommendations comprising a design philosophy for future military gen-sets. The market survey revealed that the commercial market is in a state of flux, but it is currently or will soon be capable of providing the technologies recommended here in a cost-effective manner. The recommendations, if implemented, should result in future power generation systems that are much more functional than today's gen-sets. The number of differing units necessary (both family sizes and frequency modes) to cover the medium power range would be decreased significantly, while the weight and volume of each unit would decrease, improving the transportability of the power source. Improved fuel economy and overall performance would result from more effective utilization of the prime mover in the generator. The units would allow for more flexibility and control, improved reliability, and more effective power management in the field.

Blushing and the philosophy of mind.

Science.gov (United States)

Bunge, Mario

2007-01-01

The introduction, an imaginary dialogue between a philosopher and a scientist, is followed by a brief discussion of the interactions between science, philosophy, and religion. Next comes an analysis of the three most popular philosophies of mind: classical mind-body dualism, computerism, and psychoneural monism. It is argued that the latter, held by medical psychologists since Hippocrates, and formulated explicitly by Cajal and Hebb, is the philosophy of mind that underlies contemporary cognitive and affective neuroscience. The standard objections to psychoneural monism (or materialism) are examined. Evolutionary psychology, though promissory, is judged to be more fancy than fact at its present stage. The conclusion is that the philosophy of mind is still in a poor shape, but that it can advance if it learns more from the science of mind. It would also help if scientific psychologists were to replace such tacitly dualistic expressions as "organ N instantiates (or subserves) mental function M" with "organ N performs mental function M", just as we say "the legs walk" instead of "walking is subserved by legs," and "the lungs breathe" instead of "the lungs instantiate breathing."

Investigating Philosophies Underpinning Dietetic Private Practice

Directory of Open Access Journals (Sweden)

Claudia Harper

2017-03-01

Full Text Available There is limited theory or knowledge regarding dietitians’ practice philosophies and how these philosophies are generated and incorporated into their professional practices. For the purposes of this study, a conceptual framework will explain and define the ‘philosophies’ as three different types of knowledge; episteme, techne, and phronesis. This study aimed to develop an explanatory theory of how dietitians in private practice source, utilise, and integrate practice philosophies. A grounded theory qualitative methodology was used to inform the sampling strategy, data collection, and analytical processes. Semi-structured interviews with dietitians in private practice were undertaken and data were collected and analysed concurrently. The results show that dietitians form collaborative relationships with their clients, in order to nurture change over time. They use intrinsic and intertwined forms of episteme, techne, and phronesis, which allow them to respond both practically and sensitively to their clients’ needs. The learning and integration of these forms of knowledge are situated in their own practice experience. Dietitians adapt through experience, feedback, and reflection. This study highlights that private practice offers a unique context in which dietitians deal with complex issues, by utilising and adapting their philosophies.

Modern Questions Of The Legal Philosophy

Directory of Open Access Journals (Sweden)

Gennadiy A. Torgashev

2014-06-01

Full Text Available In the present article author considers fundamental problems of law connected with equality, justice and freedom. Author proves that philosophy and law as forms of public consciousness carry out the important closely interconnected among themselves functions of the social life judgment. In the article author noted that among other forms of public consciousness law is one of difficult objects of knowledge, because law is connected with such forms of consciousness as philosophy, morals, religion, policy. The legal philosophy is the philosophical discipline having the subject the general regularities of law functioning, taken in their historical and sociocultural development, definition and the sense of legal judgment and its fundamental concepts. Law represents a set of obligatory rules of conduct (norms established by the authorized or the state. Diverse spiritual life of the society assumes a variety in the nature of law. The typology of philosophical concepts of the law and how the legal philosophy interprets legal reality is researched, various philosophical and legal concepts which are caused by two main types of rights – natural and positive are allocated. Author gives opinions of scientists, and explains own views of the author.

Introduction: film-philosophy and a world of cinemas

OpenAIRE

Martin-Jones, David

2016-01-01

This Special Section arose out of the 2014 Film-Philosophy conference,\\ud held at the University of Glasgow, which took as its theme: A World of\\ud Cinemas. The aim of both the conference theme and this resulting Special\\ud Section is to broaden the debate in film-philosophy, both in terms of a\\ud world of cinemas and a world of philosophies. This introduction considers\\ud the reasons why such an intervention is worthwhile.

Retooling Peace Philosophy

DEFF Research Database (Denmark)

Schmidt, Johannes Dragsbæk; Hersh, Jacques; Petersen-Overton, Kristofer

2010-01-01

This book documents recent and historical events in the theoretically-based practice of peace development. Its diverse collection of essays describes different aspects of applied philosophy in peace action, commonly involving the contributors’ continual engagement in the field, while offering sup...

Rethinking "Ukama" in the Context of "Philosophy for Children" in Africa

Science.gov (United States)

Ndofirepi, Amasa Philip; Shanyanana, Rachel N.

2016-01-01

This paper is a critical conceptual exploration of the contribution of the "ukama" ethic in the context of "Philosophy for Children" (The "Philosophy for Children" movement is also variously known as "philosophy in schools," "philosophy with children" and "philosophical inquiry in the…

Making Philosophy of Science Education Practical for Science Teachers

Science.gov (United States)

Janssen, F. J. J. M.; van Berkel, B.

2015-01-01

Philosophy of science education can play a vital role in the preparation and professional development of science teachers. In order to fulfill this role a philosophy of science education should be made practical for teachers. First, multiple and inherently incomplete philosophies on the teacher and teaching on what, how and why should be…

25 CFR 36.10 - Standard I-Philosophy and goals.

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Standard I-Philosophy and goals. 36.10 Section 36.10... § 36.10 Standard I—Philosophy and goals. (a) Each school shall develop a written mission statement and philosophy of education that addresses the accumulation of knowledge and development of skills, interests...

The Birth of Philosophy and the Contempt for Food

NARCIS (Netherlands)

Korthals, M.J.J.A.A.

2008-01-01

The history of philosophy of food is an unhappy one. It seems that only by denying the relevance of food for a happy life, philosophy could establish itself as a serious branch of knowledge: this is what I call the philosopher's incoherence. First with the Greeks, philosophy want to get rid of the

Santa Rita Experimental Range: 100 years (1903 to 2003) of accomplishments and contributions; conference proceedings; 2003 October 30-November 1; Tucson, AZ

Science.gov (United States)

Mitchel P. McClaran; Peter F. Ffolliott; Carleton B. Edminster

2003-01-01

The purpose of this conference was to celebrate the 100 years of accomplishments and contributions of the Santa Rita Experimental Range, the longest continuously operating research area dedicated to the sustainable management of North American rangelands. The conference consisted of one-and-a-half days of invited synthesis papers and contributed poster presentations...

What can philosophy do for psychiatry?

Science.gov (United States)

Fulford, Kenneth WM; Stanghellini, Giovanni; Broome, Matthew

2004-01-01

This article illustrates the practical impact of recent developments in the philosophy of psychiatry in five key areas: patient-centred practice, new models of service delivery, neuroscience research, psychiatric education, and the organisation of psychiatry as an international science-led discipline focused on patient care. We conclude with a note on the role of philosophy in countering the stigmatisation of mental disorder. PMID:16633476

Redefining ecological ethics: science, policy, and philosophy at Cape Horn.

Science.gov (United States)

Frodeman, Robert

2008-12-01

In the twentieth century, philosophy (especially within the United States) embraced the notion of disciplinary expertise: philosophical research consists of working with and writing for other philosophers. Projects that involve non-philosophers earn the deprecating title of "applied" philosophy. The University of North Texas (UNT) doctoral program in philosophy exemplifies the possibility of a new model for philosophy, where graduate students are trained in academic philosophy and in how to work with scientists, engineers, and policy makers. This "field" (rather than "applied") approach emphasizes the inter- and transdisciplinary nature of the philosophical enterprise where theory and practice dialectically inform one another. UNT's field station in philosophy at Cape Horn, Patagonia, Chile is one site for developing this ongoing experiment in the theory and practice of interdisciplinary philosophic research and education.

Anthropology & Philosophy

DEFF Research Database (Denmark)

The present book is no ordinary anthology, but rather a workroom in which anthropologists and philosophers initiate a dialogue on trust and hope, two important topics for both fields of study. The book combines work between scholars from different universities in the U.S. and Denmark. Thus, besid......, therefore, also inspire others to work in the productive intersection between anthropology and philosophy....

A brief history of the philosophy of time

CERN Document Server

Bardon, Adrian

2013-01-01

Adrian Bardon's A Brief History of the Philosophy of Time is a short introduction to the history, philosophy, and science of the study of time-from the pre-Socratic philosophers through Einstein and beyond. A Brief History of the Philosophy of Time covers subjects such as time and change, the experience of time, physical and metaphysical approaches to the nature of time, the direction of time, time travel, time and freedom of the will, and scientific and philosophical approaches to eternity and the beginning of time. Bardon employs helpful illustrations and keeps technical language to a minimum in bringing the resources of over 2500 years of philosophy and science to bear on some of humanity's most fundamental and enduring questions.

Satellite Assessment of Bio-Optical Properties of Northern Gulf of Mexico Coastal Waters Following Hurricanes Katrina and Rita.

Science.gov (United States)

Lohrenz, Steven E; Cai, Wei-Jun; Chen, Xiaogang; Tuel, Merritt

2008-07-10

The impacts of major tropical storms events on coastal waters include sediment resuspension, intense water column mixing, and increased delivery of terrestrial materials into coastal waters. We examined satellite imagery acquired by the Moderate Resolution Imaging Spectroradiometer (MODIS) ocean color sensor aboard the Aqua spacecraft following two major hurricane events: Hurricane Katrina, which made landfall on 29 August 2005, and Hurricane Rita, which made landfall on 24 September. MODIS Aqua true color imagery revealed high turbidity levels in shelf waters immediately following the storms indicative of intense resuspension. However, imagery following the landfall of Katrina showed relatively rapid return of shelf water mass properties to pre-storm conditions. Indeed, MODIS Aqua-derived estimates of diffuse attenuation at 490 nm (K_490) and chlorophyll (chlor_a) from mid-August prior to the landfall of Hurricane Katrina were comparable to those observed in mid-September following the storm. Regions of elevated K_490 and chlor_a were evident in offshore waters and appeared to be associated with cyclonic circulation (cold-core eddies) identified on the basis of sea surface height anomaly (SSHA). Imagery acquired shortly after Hurricane Rita made landfall showed increased water column turbidity extending over a large area of the shelf off Louisiana and Texas, consistent with intense resuspension and sediment disturbance. An interannual comparison of satellite-derived estimates of K_490 for late September and early October revealed relatively lower levels in 2005, compared to the mean for the prior three years, in the vicinity of the Mississippi River birdfoot delta. In contrast, levels above the previous three year mean were observed off Texas and Louisiana 7-10 d after the passage of Rita. The lower values of K_490 near the delta could be attributed to relatively low river discharge during the preceding months of the 2005 season. The elevated levels off Texas and

Safety philosophy of ICRP

International Nuclear Information System (INIS)

Kato, Kazuaki

1995-01-01

Measures are important as the means to realize philosophy. Accordingly, it is meaningful to take measures as the object when the philosophy of ICRP is considered. As to controllable risk factors, restraint shall be done so as to make the risk being brought about as small as possible. When it is not necessary to limit restraining means, risk-free is ideal. Ionizing radiation is one of risk factors. The risk that ICRP speaks is the loss of the probability of maintaining life. The object of radiation protection is limited to the exposure to controllable radiation, and the aim of protection is to minimize risk under the condition of as low as reasonably achievable. The philosophy of ICRP and the problems in the measures are discussed. ICRP and ICRU must reconfirm the allotment of roles. Radiation protection system is composed of system of radiation dosimetry and system of dose limitation. The mission of ICRP is to recommend political decision, and it may make the political declaration 'The radiation below a certain amount may be regarded as safe'. It is better only to recommend the conversion relation of radiation dose and risk. The desire and demand to ICRP are mentioned. (K.I.)

Interactions between science and technology and present-day philosophy

International Nuclear Information System (INIS)

1981-01-01

The authors plead for a revival of the symbiosis between science and technology and philosophy. Their contributions to the assessment of the consequences in science and technology as a task of philosophy as well as to the effects of science and technology on present-day philosophy want to give new impulses to this revival. (DG) [de

Practice and Malpractice in Philosophy of Education.

Science.gov (United States)

Popp, Jerome A.

1978-01-01

Examines educational philosophy as an area of inquiry in light of several points of view from other areas of philosophic inquiry. Topics discussed include activities engaged in by philosophers, analogues in science, theoretical vs practical inquiry, epistemic utilities in philosophy, and the scientific context of educational philosophizing. (DB)

Relations between Hume’s philosophy and Natural Law Ethics

Directory of Open Access Journals (Sweden)

Fernando Arancibia C.

2018-05-01

Full Text Available The philosophy of D. Hume has been commonly related to positivism and moral subjectivism. Though his explicit influence is undeniable in these schools of thought, it does not prevent the effective existence of relations of harmony between theories traditionally opposed to the humean philosophy. In this work I will present the convergences between the philosophy of Hume and the natural law ethics, particularly the developed by the New Natural Law Theory. I will argue the link from the following points: (a the relevance of the common life, (b the experience and (c the role of philosophy in the human behavior.

Philosophy of computing and information technology

OpenAIRE

Brey, Philip A.E.; Soraker, Johnny; Meijers, A.

2009-01-01

Philosophy has been described as having taken a “computational turn,” referring to the ways in which computers and information technology throw new light upon traditional philosophical issues, provide new tools and concepts for philosophical reasoning, and pose theoretical and practical questions that cannot readily be approached within traditional philosophical frameworks. As such, computer technology is arguably the technology that has had the most profound impact on philosophy. Philosopher...

Hurricanes Katrina and Rita: Temporary Emergency Impact Aid Provided Education Support for Displaced Students. Report to the Congressional Requesters. GAO-11-839

Science.gov (United States)

Scott, George A.

2011-01-01

In August and September 2005, Hurricanes Katrina and Rita devastated large portions of the U.S. Gulf Coast, resulting in nearly 2,000 deaths and severe damage to 305,000 houses and apartments. Thousands of families relocated to communities throughout the United States and enrolled their children in local public or private schools. Some families…

Making Philosophy of Science Education Practical for Science Teachers

Science.gov (United States)

Janssen, F. J. J. M.; van Berkel, B.

2015-04-01

Philosophy of science education can play a vital role in the preparation and professional development of science teachers. In order to fulfill this role a philosophy of science education should be made practical for teachers. First, multiple and inherently incomplete philosophies on the teacher and teaching on what, how and why should be integrated. In this paper we describe our philosophy of science education (ASSET approach) which is composed of bounded rationalism as a guideline for understanding teachers' practical reasoning, liberal education underlying the why of teaching, scientific perspectivism as guideline for the what and educational social constructivism as guiding choices about the how of science education. Integration of multiple philosophies into a coherent philosophy of science education is necessary but not sufficient to make it practical for teachers. Philosophies are still formulated at a too abstract level to guide teachers' practical reasoning. For this purpose, a heuristic model must be developed on an intermediate level of abstraction that will provide teachers with a bridge between these abstract ideas and their specific teaching situation. We have developed and validated such a heuristic model, the CLASS model in order to complement our ASSET approach. We illustrate how science teachers use the ASSET approach and the CLASS model to make choices about the what, the how and the why of science teaching.

Information Retrieval and the Philosophy of Language.

Science.gov (United States)

Blair, David C.

2003-01-01

Provides an overview of some of the main ideas in the philosophy of language that have relevance to the issues of information retrieval, focusing on the description of the intellectual content. Highlights include retrieval problems; recall and precision; words and meanings; context; externalism and the philosophy of language; and scaffolding and…

Philosophy of Education and the Deweyan Legacy.

Science.gov (United States)

Siegel, Harvey

2002-01-01

Responds to Rene Arcilla's article, "Why Aren't Philosophers and Educators Speaking to One Another?" suggesting that Deweyan philosophy of education is not the whole of philosophy of education, noting difficulties with the Deweyan view with which Arcilla is concerned, discussing problems with Arcilla's analysis of both the Deweyan view…

[Carl Friedrich von Weizsäcker's philosophy of the mind].

Science.gov (United States)

Lyre, Holger

2014-01-01

The paper deals with Carl Friedrich von Weizsäcker's position within the philosophy of mind. It turns out that Weizsäcker's ontology is based on an unorthodox conception both in the philosophy of physics and in the philosophy of mind. His quantum information theoretic reductionism is based on a subtle combination of atomism and holism, his philosophy of mind connected to this is a neutral monism, which proposes a bold intertwining of mind, matter, and space.

"Open" Philosophy or Down the Rabbit Hole?

Science.gov (United States)

Bowman, Wayne

2017-01-01

In this essay, I challenge the open-closed dualism at the heart of Allsup's project and question the very possibility of an "open" philosophy. I propose an account of music, musical instruction, and philosophy as ethically guided practices, discussing a number of practical and philosophical consequences that follow from such a view.

The Relationship between Philosophy and Culture | Agbanusi ...

African Journals Online (AJOL)

Over the years, there has been this controversy over the relationship between philosophy and culture. It is an issue that has always polarized scholars including philosophers. On one side, a group of philosophers and scholars hold the view that philosophy is distinct from culture, whereas an opposing group is of the opinion ...

The Landscape Of Philosophy Of Science

DEFF Research Database (Denmark)

Nistrup Madsen, Bodil; Hjørland, Birger; Brier, Søren

2016-01-01

In Denmark, all higher education programs must include a course on philosophy of science. Therefore, a group of researchers at Copenhagen Business School (CBS) are developing a smartphone application where information about central theoretical paradigms and concepts from philosophy of science can...... be visualized and disseminated in an easily accessible and systematic manner. This will be achieved by entering structured knowledge about concepts from philosophy of science in both Danish and English into a terminology and knowledge base which will provide the opportunity to “navigate in conceptual landscapes......” (here used metaphorically for terminological ontologies) in the same way as we navigate in maps. The result of the project will be a tool that can help students in their studies and support their information retrieval. The project is based on existing technologies and research in knowledge organization...

Philosophy and the Mirror of Nature

Directory of Open Access Journals (Sweden)

A Jafari Eskandari

2014-08-01

Full Text Available Richard McKay Rorty (1932-2007 is the American neo-pragmatist. Criticizing the prevalent issues of traditional philosophy such as truth, knowledge, objectivity, logic and philosophy, he considers epistemology a modern subject which emerged via forging the mind by Rene Descartes. In his view, separation of mind–body is an unprecedented matter created in Descartes philosophy. He thinks that, in creating such a matter, Descartes was aided by the big and strong image of human mind as a large mirror which reflects the world. Rorty states that this image is not trustable. This study investigates the view of Rorty about mind and body. The main hypothesis of this study is that Rorty does not seek solution for selecting monism or dualism or other view, and thus he prefers the annulling approach to solving approach.

Philosophy and the Mirror of Nature

Directory of Open Access Journals (Sweden)

A Jafari Eskandari

2014-09-01

Full Text Available Richard McKay Rorty (1932-2007 is the American neo-pragmatist. Criticizing the prevalent issues of traditional philosophy such as truth, knowledge, objectivity, logic and philosophy, he considers epistemology a modern subject which emerged via forging the mind by Rene Descartes. In his view, separation of mind–body is an unprecedented matter created in Descartes philosophy. He thinks that, in creating such a matter, Descartes was aided by the big and strong image of human mind as a large mirror which reflects the world. Rorty states that this image is not trustable. This study investigates the view of Rorty about mind and body. The main hypothesis of this study is that Rorty does not seek solution for selecting monism or dualism or other view, and thus he prefers the annulling approach to solving approach.

The Place of Philosophy in the Training of Teachers: Peters Revisited

Science.gov (United States)

Clark, John A.

2013-01-01

In 1964, Richard Peters examined the place of philosophy in the training of teachers. He considered three things: Why should philosophy of education be included in the training of teachers; What portion of philosophy of education should be included; How should philosophy be taught to those training to be teachers. This article explores the context…

The philosophy of Hans-Georg Gadamer / Wolfgang Drechsler

Index Scriptorium Estoniae

Drechsler, Wolfgang, 1963-

1998-01-01

Rets.rmt.: The philosophy of Hans-Georg Gadamer : a review of the philosophy of Hans-Georg Gadamer / Lewis Edwin Hahn, ed. Chicago and La Salle, IL: Open Court, 1997. (The Library of Living Philosophers, vol. XXIV)

Nonlinear terms in storm surge predictions: Effect of tide and shelf geometry with case study from Hurricane Rita

Science.gov (United States)

Rego, JoãO. L.; Li, Chunyan

2010-06-01

This study applied the finite volume coastal ocean model (FVCOM) to the storm surge induced by Hurricane Rita along the Louisiana-Texas coast. The model was calibrated for tides and validated with observed water levels. Peak water levels were shown to be lower than expected for a landfall at high tide. For low- and high-tide landfalls, nonlinear effects due to tide-surge coupling were constructive and destructive to total storm tide, respectively, and their magnitude reached up to 70% of the tidal amplitude in the Rita application. Tide-surge interaction was further examined using a standard hurricane under idealized scenarios to evaluate the effects of various shelf geometries, tides, and landfall timings (relative to tide). Nonlinearity was important between landfall position and locations within 2.5 × radius of maximum winds. On an idealized wide continental shelf, nonlinear effects reached up to 80% of the tidal amplitude with an S2 tide and up to 47% with a K1 tide. Increasing average depths by 4 m reduced nonlinear effects to 41% of the tidal amplitude; increasing the slope by a factor of 3 produced nonlinearities of just 26% of tide (both with a K1 tide). The nonlinear effect was greatest for landfalls at low tide, followed by landfalls at high tide and then by landfalls at midebb or midflood.

Checks and balances: the welcomed tension between philosophy and science.

Science.gov (United States)

Watson, Jamie Carlin; Arp, Robert

2008-03-01

There is a tension between science and philosophy, but this tension need not engender enmity or derision. Scientists and philosophers can work together, and we argue that working together is beneficial to both, even if it is sometimes uncomfortable. We offer examples of how philosophy can autonomously and effectively inform scientific practice. Science and philosophy share certain methodological concerns and practices; therefore, scientists who disregard philosophy are vulnerable to critical conceptual mistakes. If our arguments are correct, and if it can also be shown that science informs philosophy, then, while it is possible for both disciplines to operate autonomously, each should welcome the checks and balances that each provides for one another in the investigation and explanation of reality.

Humanist Principles Underlying Philosophy of Argument

Directory of Open Access Journals (Sweden)

George Boger

2008-02-01

Full Text Available This discussion reviews the thinking of some prominent philosophers of argument to extract principles common to their thinking. It shows that a growing concern with dialogical pragmatics is better appreciated as a part of applied ethics than of applied epistemology. The discussion concludes by indicating a possible consequence for philosophy of argument and invites further discussion by asking whether argumentation philosophy has an implicit, underlying moral, or even political, posture.

Philosophie et colonialisme chez Anquetil-Duperron

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Simón Gallegos Gabilondo

2010-11-01

Full Text Available Anquetil-Duperron was one of the main critics of Montesquieu’s concept of despotism, a tenacious opponent of eurocentrism and an unconventional exponent of anticolonial thought in the Enlightenment. He questioned the philosophical use of travel literature and also denounced that philosophy can be an instrument of conquest, grounding colonization’s image of the world. This article focuses on the original relationship that his works disclosed between colonialism and philosophy.

The contract of language: John Searle’s philosophy of society

NARCIS (Netherlands)

Leezenberg, M.

2011-01-01

In Making the Social World, John Searle develops what he calls a "philosophy of society", which explores the ontological status and logical structure of institutional facts like universities and baseball games. This philosophy of society crucially depends on Searle's earlier work in the philosophy

Drug resistance to inhibitors of the human double minute-2 E3 ligase is mediated by point mutations of p53, but can be overcome with the p53 targeting agent RITA.

Science.gov (United States)

Jones, Richard J; Bjorklund, Chad C; Baladandayuthapani, Veerabhadran; Kuhn, Deborah J; Orlowski, Robert Z

2012-10-01

The human double minute (HDM)-2 E3 ubiquitin ligase plays a key role in p53 turnover and has been validated preclinically as a target in multiple myeloma (MM) and mantle cell lymphoma (MCL). HDM-2 inhibitors are entering clinical trials, and we therefore sought to understand potential mechanisms of resistance in lymphoid models. Wild-type p53 H929 MM and Granta-519 MCL cells resistant to MI-63 or Nutlin were generated by exposing them to increasing drug concentrations. MI-63-resistant H929 and Granta-519 cells were resistant to Nutlin, whereas Nutlin-resistant cells displayed cross-resistance to MI-63. These cells also showed cross-resistance to bortezomib, doxorubicin, cisplatin, and melphalan, but remained sensitive to the small molecule inhibitor RITA (reactivation of p53 and induction of tumor cell apoptosis). HDM-2 inhibitor-resistant cells harbored increased p53 levels, but neither genotoxic nor nongenotoxic approaches to activate p53 induced HDM-2 or p21. Resequencing revealed wild-type HDM-2, but mutations were found in the p53 DNA binding and dimerization domains. In resistant cells, RITA induced a G(2)-M arrest, upregulation of p53 targets HDM-2, PUMA, and NOXA, and PARP cleavage. Combination regimens with RITA and MI-63 resulted in enhanced cell death compared with RITA alone. These findings support the possibility that p53 mutation could be a primary mechanism of acquired resistance to HDM-2 inhibitors in MCL and MM. Furthermore, they suggest that simultaneous restoration of p53 function and HDM-2 inhibition is a rational strategy for clinical translation.

THE QUESTION OF AFRICAN PHILOSOPHY AND KWASI wm ...

African Journals Online (AJOL)

subject qf careful scrutiny by African philosophers and others who are engaged in .... an overly nationalist attempt to restrict philosophy to country ..... philosophy in Africa at the present time is the production ... William Lovitt (New York: Harper.

Research philosophy: towards an understanding.

Science.gov (United States)

Crossan, Frank

2003-01-01

In this paper, Frank Crossan argues that the distinction between quantitative and qualitative philosophies and research methods is sometimes overstated, and that triangulation of methods in contemporary research is common. It is, therefore, important to understand the strengths and weaknesses of each approach, and this paper aims to provide the novice researcher with a basis for developing that understanding. A descriptive analysis of the philosophies of positivism and post-positivist thinking in relation to research methodology is presented both as an introduction to the philosophical basis of research, and as a sound basis from which to discuss the 'quantitative-qualitative' debate.

Logic and Philosophy of Time

DEFF Research Database (Denmark)

A.N. Prior (1914-69) in the course of the 1950s and 1960s founded a new and revolutionary paradigm in philosophy and logic. Its most central feature is the preoccupation with time and the development of the logic of time. However, this was inseparably interwoven with fundamental questions about h...... human freedom, ethics, and existence. This remarkable integration of themes also embodies an original and in fact revolutionary conception of logic. The book series, Logic and Philosophy of Time, is dedicated to a deep investigation and also the further development of Prior’s paradigm. ...

Filosofia Theoretica: Journal of African Philosophy, Culture and ...

African Journals Online (AJOL)

Filosofia Theoretica: Journal of African Philosophy, Culture and Religions: Site Map. Journal Home > About the Journal > Filosofia Theoretica: Journal of African Philosophy, Culture and Religions: Site Map. Log in or Register to get access to full text downloads.

The burden of rare cancers in Italy: the surveillance of rare cancers in Italy (RITA) project.

Science.gov (United States)

Trama, Annalisa; Mallone, Sandra; Ferretti, Stefano; Meduri, Francesca; Capocaccia, Riccardo; Gatta, Gemma

2012-01-01

The project Surveillance of rare cancers in Italy (RITA) provides, for the first time, estimates of the burden of rare cancers in Italy based on the list of rare cancers proposed in collaboration with the European project Surveillance of Rare Cancers in Europe (RARECARE). RITA analyzed data from Italian population-based cancer registries (CR). The period of diagnosis was 1988 to 2002, and vital status information was available up to December 31, 2003. Incidence rates were estimated for the period 1995-2002, survival for the years 2000-2002 (with the period method of Brenner), and complete prevalence at January 1, 2003. Rare cancers are those with an incidence <6/100,000/year. In Italy, every year there are 60,000 new diagnoses of rare cancers corresponding to 15% of all new cancer diagnoses. Five-year relative survival was on the average worse for rare cancers (53%) than for common cancers (73%). A total of 770,000 patients were living in Italy in 2008 with a diagnosis of a rare cancer, 22% of the total cancer prevalence. Our estimates constitute a useful base for further research and support the idea that rare cancers are a public health problem that deserves attention. Centers of expertise for rare cancers that pool cases, expertise and resources could ensure an adequate clinical management for these diseases. Our data also showed that cancer registries are suitable sources of data to estimate incidence, prevalence and survival for rare cancers and should continue to monitoring rare cancers in Italy.

The new philosophy of psychiatry: its (recent) past, present and future: a review of the Oxford University Press series International Perspectives in Philosophy and Psychiatry

Science.gov (United States)

Banner, Natalie F; Thornton, Tim

2007-01-01

There has been a recent growth in philosophy of psychiatry that draws heavily (although not exclusively) on analytic philosophy with the aim of a better understanding of psychiatry through an analysis of some of its fundamental concepts. This 'new philosophy of psychiatry' is an addition to both analytic philosophy and to the broader interpretation of mental health care. Nevertheless, it is already a flourishing philosophical field. One indication of this is the new Oxford University Press series International Perspectives in Philosophy and Psychiatry seven volumes of which (by Bolton and Hill; Bracken and Thomas; Fulford, Morris, Sadler, and Stanghellini; Hughes, Louw, and Sabat; Pickering; Sadler; and Stanghellini) are examined in this critical review.

Secular Life Philosophy as a Subject in Schools in Norway.

Science.gov (United States)

Horn, Kristian

1981-01-01

In Norway changes in legislation in recent years have loosened the firm hold of Christian philosophy in the schools and given room for alternative secular philosophy. This article presents background information and an outline of the basic plan for life philosophy as a school subject. (Author/SJL)

Sociology as Moral Philosophy (and Vice Versa).

Science.gov (United States)

Vandenberghe, Frédéric

2017-11-01

In this article, I want to make an attempt to reconnect sociology to moral philosophy and moral philosophy to sociology. The thesis I want to defend is that sociology continues by other means the venerable tradition of practical and moral philosophy. Like its forebears, it stands and falls with a defense of "practical wisdom" (Aristotle) and "practical reason" (Kant). The development of a moral sociology presupposes, however, that one recognizes and rejects Max Weber's theory of axiological neutrality as an extremist position and that one carefully articulates prescriptive and descriptive, internal and external, as well as observer and actor positions. © 2017 Canadian Sociological Association/La Société canadienne de sociologie.

Beyond Cross- Cultural Philosophy: Towards a New Enlightenment

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Detlev Quintern

2017-12-01

Full Text Available The acculturalization of humanities from the late 1980ies onwards led not only to imagined different worlds (e.g. West / Islam, postmodernity overshadowed also common grounds of world`s philosophies. Christianity and Islam share far more than what might separate them, and we find Islam in „the West “as Christianity „in the East“. The Logos of Life Philosophy as developed by Anna-Teresa Tymieniecka (1923-2014 strives towards deciphering the deep layers of philosophy and its common grounds. Tracing back to Gnostic, Platonic (neo-platonic and Islamic shaped philosophies - Ikhwan as-Safa will serve as an example - the Logos of Life / Aql Al-Kulli (universal reason will be historicized in the following while introducing approaches towards a New Enlightenment (A.-T. Tymieniecka as an alternative to the current crisis in meta-sciences

Philosophy in Schools: A Catholic School Perspective

Science.gov (United States)

Whittle, Sean

2015-01-01

This article builds on the recent Special Interest issue of this journal on "Philosophy for Children in Transition" (2011) and the way that the debate about philosophy in schools has now shifted to whether or not it ought to be a compulsory part of the curriculum. This article puts the spotlight on Catholic schools in order to present a…

Iran's Implicit Philosophy of Education

Science.gov (United States)

Bagheri Noaparast, Khosrow

2018-01-01

This paper aims to extract Iran's philosophy of education from two sources of the constitution and the course of practice in educational institutions. Regarding the first source, it is argued that parallel to the two main threads of the constitution, Iran's main elements of philosophy of education are expected to be derived from; (1) Islam and (2)…

Teaching Philosophies Guiding Sexuality Instruction in US Colleges and Universities

Science.gov (United States)

Wagner, Laurie M.; Eastman-Mueller, Heather P.; Oswalt, Sara B.; Nevers, Joleen M.

2017-01-01

Teaching philosophies are central to the approach of pedagogical strategies but there has been little examination of discipline-specific teaching philosophies. This study addresses a significant gap in the literature by discussing the teaching philosophies of 122 instructors of sexuality courses. Sexuality education is unique compared to most…

A process for updating a philosophy of education statement.

Science.gov (United States)

Gambescia, Stephen F

2013-01-01

Most health education specialists have been introduced to the idea of having a philosophy of education statement. Although some in the field have been writing about this career development exercise, little has been written about the process of developing one's philosophy of education statement. This brief essay explains a sample process health education specialists can use to create or update their philosophy of education statement. The author gives a firsthand account of a systematic, disciplined, intellectually liberating, and reflective approach to articulating one's philosophy of education statement, by considering the writings of select intellectual giants who have acted on human experience, thought, and practice in education. A philosophy of education statement should be useful to any health education specialist regardless of type of work, site, position in the organization, population served, or health topic. The resultant updated and precisely written statement serves to sharpen a health education specialist's future role as a health educator, as well as contribute to his or her journey in lifelong learning.

Philosophy of astrobiology: some recent developments

Science.gov (United States)

Kolb, Vera M.

2015-09-01

We present some recent developments in philosophy of astrobiology which illustrate usefulness of philosophy to astrobiology. We cover applications of Aristotelian views to definition of life, of Priest's dialetheism to the question if viruses are alive, and various thought experiments in regard to these and other astrobiology issues. Thought experiments about the survival of life in the Solar system and about the role of viruses at the beginning and towards the end of life are also described.

Interaktywna edukacja filozoficzna: Na Targowisku Ujawnień [Interactive philosophy teaching: At the fair of disclosure

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Katarzyna Kuczyńska

2014-03-01

Full Text Available The text consists of the theoretical introduction Interactive philosophy teaching, written by Katarzyna Kuczyńska, followed by a presentation (with a commentary of the philosophical workshop script At the Fair of Disclosures, created by Sebastian Wachowiak. The theoretical part refers to the idea of philosophy as a form of human acti- vity that stays in a strict correlation with everyday life. Using the idea as a referential point, the author distinguishes the following issues: (a the process of philosophical thinking, (b the results of this process – philosophical knowledge, (c the know- ledge of philosophy, as well as intellectual competence, crucial for developing one’s philosophical culture. She also provides an interactive model of teaching philosophy at school as the one she considers the most favorable. According to the given point of view, interactive philosophy teaching: (a points out the correlation of philosophical questions with existential experience of the individuals; (b creates environment for active philosophising for the students (the didactic situation aims at initiating the knowledge manufacturing process rather than simply reproducing the knowledge. Sebastian Wachowiak’s script At the Fair of Disclosures is an example of creat- ing educational situation within the interactive model of philosophy teaching. The goal of the lesson is to deepen the students’ understanding of identity as a category described through its public and social as well as intimate and private dimension (to show the multidimensionality of human life in public and social space; to re- cognise the moral threats resulting from the identity exposure. During the first part of the lesson, while the students are participating in the designed didactic game, the issue selected in accordance to the above criteria becomes the object of students’ experience. The second part of the lesson is a discussion which aims at stimulating the students

Homage to Rita Levi-Montalcini, the queen of modern neuroscience.

Science.gov (United States)

Aloe, Luigi; Chaldakov, George N

2013-08-01

The first cell growth factor, nerve growth factor (NGF), was discovered by Rita Levi-Montalcini (RLM) in the early 1950s. Originally identified as neurite outgrowth-stimulating factor, later studies revealed that non-neuronal cells, including immune cells, endothelial cells, cardiomyocytes, pancreatic beta cells, prostate epithelial and adipose tissue cells, were also targets for and/or sources of NGF. Nerve growth factor is well recognised as mediating multiple biological phenomena, ranging from the neurotrophic through immunotrophic and epitheliotrophic to metabotrophic effects. Consequently, NGF and other members of the neurotrophin family are implicated in the pathogenesis of a large spectrum of neuronal and non-neuronal diseases, ranging from Alzheimer's and other neurodegenerative diseases to atherosclerosis and cardiometabolic disorders. Recent studies have demonstrated the therapeutic potentials of NGF in these conditions, including ocular and cutaneous diseases. NGF TrkA receptor antagonists emerged as novel drugs for pain, prostate and breast cancer, melanoma and urinary bladder syndromes. Here, we briefly describe the 'unpredictable' ideogenesis of the discovery of NGF, a eureka in the neuroscience. © 2013 International Federation for Cell Biology.

Beyond Identity: the Dynamic Self at the Intersection of Performance Philosophy and the Philosophy of Science

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Sibila Petlevski

2014-07-01

Full Text Available In this article we advocate the methodological feedback loop in the study of the dynamical self at the crossroads of performance philosophy, (artistic performance, and the philosophy of science. We point to the importance of the dynamics of methodology transfer between arts and sciences and the “interactive continuum” proposed by Newman & Benz in 1998. In the first part of this paper we give a comparative review of the research context relevant for our field of study, and we explain our research hubs in approaching the concept of “performance”. We suggest the possibility to define our filed of research in three equally legitimate ways: as philosophy-of-performance, philosophy-as-performance and performance-as-philosophy. In our recent work we are primarily interested in artistic performances that incorporate elements of artistic practice in the methodology of research output (Frayling 1993, as well as in the potentials of performative aspects of scientific praxis and methodology. However, the conceptual background relevant for this paper is in the field of process philosophy and its relation to science (Birkhard’s “interactivist model” 2009; Campbell’s “process-based model for an interactive ontology” 2009. We attribute particular importance to the notion of “autopoietic feedback” (Maturana and Varela 1974; Luhmann 1990. The second part addresses the issue of transcending identity in the representations of the self and the other; the relationship between Theory-Theory (TT and Simulation Theory (ST, as well as some recent attempts at combining different theories of mind (e.g. Barlassina 2013. We also deal with the notion of “embodied praxis” (Gallagher and Meltzoff 1996; we mention some neuroscientific insights into the similar phenomena, and – commenting on the importance of the dialogue between neuroscientists and philosophers (Changeux and Ricour – we give an example of an enactive approach to understanding

Approaching Political Philosophy through the Critique of Liberalism

DEFF Research Database (Denmark)

Sørensen, Asger

2014-01-01

Understanding political philosophy as practical implies reflecting on principles as well as on material matters, on justice as well as on government. Liberalism is the main challenge to political philosophy, since its optimistic laissez faire attitude denies the legitimacy of political government...

What is philosophy of medicine? : (Che cos’è la filosofia della medicina?)

NARCIS (Netherlands)

Kingma, E.M.

2011-01-01

Philosophy of Medicine is considered a new and emerging discipline. This paper presents an overview of philosophy of medicine, discusses its relation to bioethics and to other areas of philosophy, and introduces three potential topics for research in the philosophy of medicine: concepts of health

Leaving Libertarianism: : Social Ties in Robert Nozick's New Philosophy

OpenAIRE

Herbjørnsrud, Dag

2002-01-01

SUMMARY This thesis Leaving Libertarianism: Social Ties in Robert Nozick s New Philosophy challenges the general and most widespread portrayals of the American philosopher Robert Nozick (1938-2002) by studying the notion of social ties in his later philosophy. The point of departure is the present descriptions of Nozick s philosophy. Mostly these depictions are based upon three postulates: That Nozick is an extreme individualist, that the libertarian Anarchy, State, and Utopia (1...

Discussion Note: Contemporary Philosophy Versus the Free Society

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Tibor R. Machan

2010-11-01

Full Text Available Some libertarians are impatient with philosophical discussions and even dismiss philosophy as not needed to make the case for the free society. I dispute this and indicate why. As many have found, even to dismiss philosophy, one needs a bit of it!

Wrestling with Philosophy: Improving Scholarship in Higher Education

Science.gov (United States)

Kezar, Adrianna

2004-01-01

Method is usually viewed as completely separate from philosophy or theory, focusing instead on techniques and procedures of interviewing, focus groups, observation, or statistical analysis. Several texts on methodology published recently have added significant sections on philosophy, such as Creswell's (1998) Qualitative inquiry and research…

R.G. Collingwood, Analytical Philosophy And Logical Positivism

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James Connelly

2009-10-01

Full Text Available R.G. Collingwood is not normally associated with analytic philosophy, neither negatively nor positively. He neither regarded himself, nor was regarded by his contemporaries and their successors, as an analytical philosopher. However, the story is more interestingly complex than this, both because Collingwood is one of the few pre-analytics in the UK who continues to be of interest to current analytical philosophers, especially in relation to the philosophy of art and history and his conception of metaphysics, and because he mounted a critique of analytical philosophy in the years of its emergence.

Requirements to be met by a safety philosophy

International Nuclear Information System (INIS)

Hahn, L.

1990-01-01

The author's assessment of the use of safety philosophies is that, since 'safety philosophers' still are not certain whether a safety philosophy ought to be applicable to just one, particular technology, or rather to a variety of different technologies, there is reason to state that the required ethical, philosophical and political foundations to build a safety philosophy on are still missing. And this, the author presumes, is one of the reasons why our society to a far extent is incapable of acting, faced not only with the nuclear issue, but also with the present and future ecological challenge. (orig./DG) [de

The Unreasonable Destructiveness of Political Correctness in Philosophy

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Manuel Doria

2017-08-01

Full Text Available I submit that epistemic progress in key areas of contemporary academic philosophy has been compromised by politically correct (“PC” ideology. First, guided by an evolutionary account of ideology, results from social and cognitive psychology and formal philosophical methods, I expose evidence for political bias in contemporary Western academia and sketch a formalization for the contents of beliefs from the PC worldview taken to be of core importance, the theory of social oppression and the thesis of anthropological mental egalitarianism. Then, aided by discussions from contemporary epistemology on epistemic values, I model the problem of epistemic appraisal using the frameworks of multi-objective optimization theory and multi-criteria decision analysis and apply it to politically correct philosophy. I conclude that philosophy guided by politically correct values is bound to produce constructs that are less truth-conducive and that spurious values which are ideologically motivated should be abandoned. Objections to my framework stemming from contextual empiricism, the feminine voice in ethics and political philosophy are considered. I conclude by prescribing the epistemic value of epistemic adequacy, the contextual value of political diversity and the moral virtue of moral courage to reverse unwarranted trends in academic philosophy due to PC ideology.

Three views of logic mathematics, philosophy, and computer science

CERN Document Server

Loveland, Donald W; Sterrett, S G

2014-01-01

Demonstrating the different roles that logic plays in the disciplines of computer science, mathematics, and philosophy, this concise undergraduate textbook covers select topics from three different areas of logic: proof theory, computability theory, and nonclassical logic. The book balances accessibility, breadth, and rigor, and is designed so that its materials will fit into a single semester. Its distinctive presentation of traditional logic material will enhance readers' capabilities and mathematical maturity. The proof theory portion presents classical propositional logic and first-orde

The history of the philosophy of management and corporations

DEFF Research Database (Denmark)

Rendtorff, Jacob Dahl

2013-01-01

In this chapter, the history of philosophy of management is discussed with a focus on the search for legitimacy in the Judeo-Christian tradition. This is the basis for evaluating modern concepts of the economics of the philosophy of management and corporations. The chapter also presents the neoli...... the neoliberal paradigm of the philosophy of management and the attempt to search for another economy beyond rational individual utility maximization. Here we move toward business ethics, CSR, and corporate citizenship....

Interaction between Philosophy of Education and Teaching Practice

Science.gov (United States)

Bim-Bad, Boris Michailovich; Egorova, Lioudmila Ivanovna

2016-01-01

The article attempts to analyse the interaction between philosophy of education and teaching practice. Such area of learning as "philosophy of education" is defined, genesis and dynamics of practice as universals of human existence are traced; such concepts as "practice," "teaching practice" are analysed in view of…

The borderlands between science and philosophy: an introduction.

Science.gov (United States)

Pigliucci, Massimo

2008-03-01

Science and philosophy have a very long history, dating back at least to the 16th and 17th centuries, when the first scientist-philosophers, such as Bacon, Galilei, and Newton, were beginning the process of turning natural philosophy into science. Contemporary relationships between the two fields are still to some extent marked by the distrust that maintains the divide between the so-called "two cultures." An increasing number of philosophers, however, are making conceptual contributions to sciences ranging from quantum mechanics to evolutionary biology, and a few scientists are conducting research relevant to classically philosophical fields of inquiry, such as consciousness and moral decision-making. This article will introduce readers to the borderlands between science and philosophy, beginning with a brief description of what philosophy of science is about, and including a discussion of how the two disciplines can fruitfully interact not only at the level of scholarship, but also when it comes to controversies surrounding public understanding of science.

History, Applications, and Philosophy in Mathematics Education: HAPh--A Use of Primary Sources

Science.gov (United States)

Jankvist, Uffe Thomas

2013-01-01

The article first investigates the basis for designing teaching activities dealing with aspects of history, applications, and philosophy of mathematics in unison by discussing and analyzing the different "whys" and "hows" of including these three dimensions in mathematics education. Based on the observation that a use of history, applications, and…

Systems thinking, critical realism and philosophy a confluence of ideas

CERN Document Server

Mingers, John

2014-01-01

Systems Thinking, Critical Realism and Philosophy: A Confluence of Ideas seeks to re-address the whole question of philosophy and systems thinking for the twenty first century and provide a new work that would be of value to both systems and philosophy. This is a highly opportune time when different fields - critical realism, philosophy of science and systems thinking - are all developing around the same set of concepts and yet not realizing it. This book will be of interest to the academic systems community worldwide and due to it's interdisciplinary coverage, it will also

Immanent philosophy of X.

Science.gov (United States)

Hendry, Robin Findlay

2016-02-01

In this paper I examine the relationship between historians, philosophers and sociologists of science, and indeed scientists themselves. I argue that (i) they co-habit a shared intellectual territory (science and its past); and (ii) they should be able to do so peacefully, and with mutual respect, even if they disagree radically about how to describe the methods and results of science. I then go on to explore some of the challenges to mutually respectful cohabitation between history, philosophy and sociology of science. I conclude by identifying a familiar kind of project in the philosophy of science which seeks to explore the worldview of a particular scientific discipline, and argue that it too has a right to explore the shared territory even though some historians and sociologists may find it methodologically suspect. Copyright © 2015 Elsevier Ltd. All rights reserved.

Satellite Assessment of Bio-Optical Properties of Northern Gulf of Mexico Coastal Waters Following Hurricanes Katrina and Rita

Directory of Open Access Journals (Sweden)

Merritt Tuel

2008-07-01

Full Text Available The impacts of major tropical storms events on coastal waters include sediment resuspension, intense water column mixing, and increased delivery of terrestrial materials into coastal waters. We examined satellite imagery acquired by the Moderate Resolution Imaging Spectroradiometer (MODIS ocean color sensor aboard the Aqua spacecraft following two major hurricane events: Hurricane Katrina, which made landfall on 29 August 2005, and Hurricane Rita, which made landfall on 24 September. MODIS Aqua true color imagery revealed high turbidity levels in shelf waters immediately following the storms indicative of intense resuspension. However, imagery following the landfall of Katrina showed relatively rapid return of shelf water mass properties to pre-storm conditions. Indeed, MODIS Aqua-derived estimates of diffuse attenuation at 490 nm (K_490 and chlorophyll (chlor_a from mid-August prior to the landfall of Hurricane Katrina were comparable to those observed in mid-September following the storm. Regions of elevated K_490 and chlor_a were evident in offshore waters and appeared to be associated with cyclonic circulation (cold-core eddies identified on the basis of sea surface height anomaly (SSHA. Imagery acquired shortly after Hurricane Rita made landfall showed increased water column turbidity extending over a large area of the shelf off Louisiana and Texas, consistent with intense resuspension and sediment disturbance. An interannual comparison of satellite-derived estimates of K_490 for late September and early October revealed relatively lower levels in 2005, compared to the mean for the prior three years, in the vicinity of the Mississippi River birdfoot delta. In contrast, levels above the previous three year mean were observed off Texas and Louisiana 7-10 d after the passage of Rita. The lower values of K_490 near the delta could be attributed to relatively low river discharge during the preceding months of the 2005 season. The elevated levels

The Importance of Teaching a Win-Win Philosophy.

Science.gov (United States)

Brainard, Alan J.

Most people are raised in a traditional environment which teaches that someone-winning implies that someone-loses. However, psychology and the examples provided in the Watergate scandal demonstrate that such a philosophy is neither productive nor beneficial. A "win-win" philosophy of cooperation, not competition, is needed for…

Filosofia Theoretica: Journal of African Philosophy, Culture and ...

African Journals Online (AJOL)

Addressing Uduma's Africanness of a Philosophy Question and Shifting the Paradigm from Metaphilosophy to Conversational Philosophy · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. JO Chimakonam, 33-50. http://dx.doi.org/10.4314/ft.v4i1.3 ...

Philosophy as Pharmakon : Towards the hermeneutics of healing ...

African Journals Online (AJOL)

The history of philosophy gives us an insight into what good life portends. Plato, Aristotle and other ancient classics developed guiding principles on the ethical basis for behavioural cognition and existential logic. Hence, the interest of philosophy in other disciplines such as medicine and psychology is well known.

Notes toward a Philosophy of Action Learning Research

Science.gov (United States)

Coghlan, David; Coughlan, Paul

2010-01-01

The philosophical foundations of action learning research have not received a great deal of attention. In the context of action learning postgraduate and professional programmes in universities, articulation of a philosophy of action learning research seems timely and appropriate. This article explores a philosophy of action learning research,…

Positivism and Nigeria's philosophy of education | Ochulor | Global ...

African Journals Online (AJOL)

This paper examined from a positivist perspective, the adequacy or otherwise of Nigeria's Philosophy of Education. We identified the educational strategies of positivism and tried to discover whether they form part of Nigeria's Philosophy of Education. We discovered that positivism adopts the empiricist – inductivist model of ...

Land area change and fractional water maps in the Chenier Plain, Louisiana, following hurricane Rita

Science.gov (United States)

Palaseanu-Lovejoy, M.; Kranenburg, C.; Brock, J. C.

2009-12-01

The objective of this study is to develop a fractional water map at 30-m resolution scale using QuickBird and/or IKONOS high-resolution imagery as dependent variable to investigate the impact of hurricane Rita in the Chenier Plain, Louisiana. Eleven different indices were tested to obtain a high-resolution land / water classification on QuickBird (acquired on 05/23/2003) and IKONOS (acquired on 03/25/2006) images. The percent area covered by water in the high resolution images varied from 22 to 26% depending on the index used , with the simple ratio index (red band / NIR band) accounting for the lowest percent and the blue ratio index (blue band / sum(all bands)) for the highest percent. Using the ERDAS NLCD (National Land Cover Data) Mapping tool module, 100, 000 stratified random sample points with minimum 1000 points per stratum were selected from the high resolution dependent variable as training information for the independent variable layers. The rules for the regression tree were created using the data mining software Rulequest Cubist v. 2.05. This information was used to generate a fractional water map for the entire Landsat scene. The increase in water areas of about 10 - 15% between 2003 to 2006, as well as temporary changes in the water - land configurations are attributed to remnant flooding and removal of aquatic vegetation caused by hurricane Rita, and water level variations caused by tidal and / or meteorological variations between the acquisition dates of the satellite images. This analysis can assist in monitoring post-hurricane wetland recovery and assess trends in land loss due to extreme storm events, although estimation of permanent land loss cannot be made until wetland areas have the opportunity to recover from hurricane impacts.

Philosophy of adult education and the implication for agricultural ...

African Journals Online (AJOL)

Philosophy of adult education and the implication for agricultural extension service. ... The paper highlights the relationhip between adult education and extension using the philosophy as a fulcrum between both. The paper further reiterated ...

Some Main Features of Wittgenstein´s Philosophy

OpenAIRE

Brock, Steen

2006-01-01

Der er tale om to kapitler fra et bogmanuskript om Wittgensteins filosofi. Teksten laver en systematisk kobling mellem sprogfilosofien, matematikfilosofien, psykologiens filosofi og naturvidenskabs-filosofien. Two chapters from a book manuscript, where four parts of Wittgenstein´s philosophy are systematically interconnected, philosophy of language, mathematics, psychology and natural science

Introduction to Christian philosophy | Nnaji | Sophia: An African ...

African Journals Online (AJOL)

This paper revisits and reconstructs the beginning of medieval philosophy (i.e. Renaissance philosophy) from about 400CE-1650CE when Catholic Reverend Fathers used the tools of Aristotelian syllogisms to argue (in order) to establish the existence of God, not only the genuineness of the Christian religion. The, method ...

Thinking Images: Doing Philosophy in Film and Video

Science.gov (United States)

Parkes, Graham

2009-01-01

Over the past several decades film and video have been steadily infiltrating the philosophy curriculum at colleges and universities. Traditionally, teachers of philosophy have not made much use of "audiovisual aids" in the classroom beyond the chalk board or overhead projector, with only the more adventurous playing audiotapes, for example, or…

From philosophy to science (to natural philosophy): evolutionary developmental perspectives.

Science.gov (United States)

Love, Alan C

2008-03-01

This paper focuses on abstraction as a mode of reasoning that facilitates a productive relationship between philosophy and science. Using examples from evolutionary developmental biology, I argue that there are two areas where abstraction can be relevant to science: reasoning explication and problem clarification. The value of abstraction is characterized in terms of methodology (modeling or data gathering) and epistemology (explanatory evaluation or data interpretation).

Radiation protection measurement. Philosophy and implementation

International Nuclear Information System (INIS)

Recht, P.; Lakey, J.R.A.

1975-01-01

A selection from the proceedings of the International Symposium held by the U.K. Society for radiological protection in June 1974 was presented. The central theme was the philosophy of radiation protection measurement and its interpretation although some specific areas of good health physics practice were included. The 28 papers selected were chosen to be either representative of the central theme or of wider interest. The papers have been grouped in 6 main sections: philosophy of measurements; interpretation of measurements; implementation by legislation and monitoring; radiation exposure and control; reactor safety and siting; accidents

Being qua becoming: Aristotle's "Metaphysics", quantum physics, and Process Philosophy

Science.gov (United States)

Johnson, David Kelley

In Aristotle's First Philosophy, science and philosophy were partners, but with the rise of empiricism, went their separate ways. Metaphysics combined the rational and irrational (i.e. final cause/unmoved mover) elements of existence to equate being with substance, postulating prime matter as pure potential that was actuated by form to create everything. Modern science reveres pure reason and postulates its theory of being by a rigorous scientific methodology. The Standard Model defines matter as energy formed into fundamental particles via forces contained in fields. Science has proved Aristotle's universe wrong in many ways, but as physics delves deeper into the quantum world, empiricism is reaching its limits concerning fundamental questions of existence. To achieve its avowed mission of explaining existence completely, physics must reunite with philosophy in a metascience modeled on the First Philosophy of Aristotle. One theory of being that integrates quantum physics and metaphysics is Process Philosophy.

110 Theory and Practice in Philosophy and Education: A ...

African Journals Online (AJOL)

First Lady

2013-01-28

Jan 28, 2013 ... philosophy of education in its content and method is theoretical but must ... Philosophy, like psychology, sociology and history is an abstract, .... tested through the use and application of dialectics, logic and statistics among.

UTILITARIANISM AS A PHILOSOPHY OF EDUCATION

Directory of Open Access Journals (Sweden)

Elena N. Yarkova

2016-01-01

Full Text Available Aim. The article is devoted to the representation of utilitarianism as the philosophy of education. The main problem is the relevance of utilitarian strategies for the present stage of development of education in Russia. Methods, results and scientific novelty. Utilitarianism is presented as an educational strategy, nominating at the forefront the principle of usefulness of education, positioning education as a means of achieving social and individual wellbeing. The author represents the basic principles of utilitarian philosophy, and also reveals how these principles have been refracted in the philosophy of education using the methods of value-semantic reduction and qualitative content analysis. The first part of the article is devoted to the history of utilitarianism as the philosophy of education in the Euro-American pedagogical culture, as well as the analysis of modern utilitarianism as widely existent in this culture of philosophy of education. In the second part of the article the author explicates the role of utilitarianism in the education strategies of the Russian pedagogical culture, past and present. The main idea of the article is the idea that we have two value-semantic forms of utilitarianism: narrowly understood (tactical utilitarianism and widespread (strategic utilitarianism. Within the tactical utilitarianism as socially and/or individually useful education is considered to be vocationalism, claimed the currently market education. This kind of education is characterized by its focus on learning/teaching applied science and recognition of the futility of Sciences fundamental and philosophical. Under the strategic utilitarianism individually and/or socially beneficial is considered: first, the versatile education characterized by its focus on learning/teaching not only applications, but also fundamental and philosophical disciplines, secondly, eclectic education aimed at obtaining different professional competences. Versatile

Les origines de la philosophie analytique de la religion

Directory of Open Access Journals (Sweden)

Nicholas Wolterstorff

2012-07-01

Full Text Available Il y a soixante ans, il y avait peu de philosophie de la religion et à peu près rien en ce qui concerne la théologie philosophique ; aujourd’hui, la philosophie de la religion en général, et la théologie philosophique en particulier, prospèrent dans la tradition analytique de la philosophie. Mon but est d’expliquer pourquoi la situation actuelle est si différente de celle d’il y a soixante ans.