PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP, VOLUME 66

International Nuclear Information System (INIS)

OGAWA, A.

2005-01-01

The RIKEN BNL Research Center (RSRC) was established in April 1997 at Brookhaven National Laboratory. It is funded by the 'Rikagaku Kenkyusho (RIKEN, The Institute of Physical and Chemical Research) of Japan. The Center is dedicated to the study of strong interactions, including spin physics, lattice QCD, and RHIC physics through the nurturing of a new generation of young physicists. The RBRC has both a theory and experimental component. At present the theoretical group has 4 Fellows and 3 Research Associates as well as 11 RHIC Physics/University Fellows (academic year 2003-2004). To date there are approximately 30 graduates from the program of which 13 have attained tenure positions at major institutions worldwide. The experimental group is smaller and has 2 Fellows and 3 RHIC Physics/University Fellows and 3 Research Associates, and historically 6 individuals have attained permanent positions. Beginning in 2001 a new RIKEN Spin Program (RSP) category was implemented at RBRC. These appointments are joint positions of RBRC and RIKEN and include the following positions in theory and experiment: RSP Researchers, RSP Research Associates, and Young Researchers, who are mentored by senior RBRC Scientists, A number of RIKEN Jr. Research Associates and Visiting Scientists also contribute to the physics program at the Center. RBRC has an active workshop program on strong interaction physics with each workshop focused on a specific physics problem. Each workshop speaker is encouraged to select a few of the most important transparencies from his or her presentation, accompanied by a page of explanation. This material is collected at the end of the workshop by the organizer to form proceedings, which can therefore be available within a short time. To date there are sixty nine proceedings volumes available. The construction of a 0.6 teraflops parallel processor, dedicated to lattice QCD, begun at the Center on February 19, 1998, was completed on August 28, 1998 and is still

Site-Specific Waste Management Instruction - 100-DR-1 Group 2 Sites

International Nuclear Information System (INIS)

Jackson, R.W.

1998-01-01

This site-specific waste management instruction (SSWMI) provides guidance for the management of wastes that may be generated during the excavation and remediation of the 100-DR-1 Group 2 sites. The management of waste generated as a result of these activities will be as directed in this SSWMI. This SSWMI will be revised to incorporate guidance for management of wastes encountered that are not addressed in this SSWMI

Superheavy research at RIKEN

International Nuclear Information System (INIS)

Morita, Kosuke

2010-01-01

At RIKEN, Japan, we performed experiments to study the productions and decays of the heaviest elements produced by 208 Pb- and 209 Bi- based 'cold fusion' reactions. A gas-filled recoil separator GARIS was used for the study. In the study of 209 Bi( 70 Zn, n) reaction, we observed two decay chains originating from an isotope of the 113th element, 178 113, which were assigned firstly by generic correlation of the alpha decay chains connected into the previously known decay of 266 Bh and 262 Db via previously unknown alpha decays of 278 113, 274 Rg, and 270 Mt. In addition, decay properties of an isotope 266 Bh and its daughter nucleus 262 Db produced by the 248 Cm( 23 Na, 5n) reaction were studied. 266 Bh was clearly identified from the correlation of the known nuclide, 262 Db, providing further confirmation of the discovery of 278 113.

PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP, VOLUME 72, RHIC SPIN COLLABORATION MEETINGS XXXI, XXXII, XXXIII

International Nuclear Information System (INIS)

OGAWA, A.

2005-01-01

The RIKEN BNL Research Center (RBRC) was established in April 1997 at Brookhaven National Laboratory. It is funded by the ''Rikagaku Kenkyusho'' (RIKEN, The Institute of Physical and Chemical Research) of Japan. The Center is dedicated to the study of strong interactions, including spin physics, lattice QCD, and RHIC physics through the nurturing of a new generation of young physicists. The RBRC has both a theory and experimental component. At present the theoretical group has 4 Fellows and 3 Research Associates as well as 11 RHIC Physics/University Fellows (academic year 2003-2004). To date there are approximately 30 graduates from the program of which 13 have attained tenure positions at major institutions worldwide. The experimental group is smaller and has 2 Fellows and 3 RHIC Physics/University Fellows and 3 Research Associates, and historically 6 individuals have attained permanent positions. Beginning in 2001 a new RIKEN Spin Program (RSP) category was implemented at RBRC. These appointments are joint positions of RBRC and RIKEN and include the following positions in theory and experiment: RSP Researchers, RSP Research Associates, and Young Researchers, who are mentored by senior RBRC Scientists. A number of RIKEN Jr. Research Associates and Visiting Scientists also contribute to the physics program at the Center. RBRC has an active workshop program on strong interaction physics with each workshop focused on a specific physics problem. Each workshop speaker is encouraged to select a few of the most important transparencies from his or her presentation, accompanied by a page of explanation. This material is collected at the end of the workshop by the organizer to form proceedings, which can therefore be available within a short time. To date there are seventy-two proceeding volumes available. The construction of a 0.6 teraflops parallel processor, dedicated to lattice QCD, begun at the Center on February 19, 1998, was completed on August 28, 1998 and is still

RIKEN RI Beam Factory project

Energy Technology Data Exchange (ETDEWEB)

Yano, Yasushige; Goto, Akira; Katayama, Takeshi [Institute of Physical and Chemical Research, Wako, Saitama (Japan)

1997-03-01

The RARF proposes `RIKEN RI Beam Factory` as a next facility-expanding project. The factory makes it the primary aim to provide RI (Radioactive Isotope) beams covering over the whole atomic-mass range with the world-highest intensity in a wide energy range up to several hundreds MeV/nucleon. These RI beams are generated by the fragmentation of high-intensity heavy-ion beams. For the efficient production heavy-ion energies will be boosted up to over 100 MeV/nucleon even for very heavy ions by a K2500-MeV superconducting ring cyclotron serving as a post accelerator of the existing K540-MeV ring cyclotron. A new type of experimental installation called `MUSES` (Multi-USe Experimental Storage rings) will be constructed as well. With MUSES, various types of unique colliding experiments will become possible. (author)

Drømmejobbet

DEFF Research Database (Denmark)

Harrebye, Silas

2012-01-01

Medarbejdere vil i fremtiden også kunne arbejde, mens de sover. Virksomheder tilbyder snart deres ansatte interne kurser i ‘lucid dreaming’. Disse giver mulighed for, at man i sine drømme bliver bevidst om, at man drømmer og således kan manipulere dem. Det skal nu udnyttes. Management...

Charged particle activation analysis at RIKEN. Past, present and future

International Nuclear Information System (INIS)

Nozaki, T.

2008-01-01

From 1960s to 1980s many groups in the world actively studied and utilized charged particle activation analysis (CPAA) mainly for absolute determination of B, C, N, and O in high-purity substances, particularly semiconductor materials. Here, after a short historical note on CPAA, works of the author's group mainly at RIKEN are outlined and then his opinion is shown about how to anticipate on the present shrinking of CPAA. (author)

PROCEEDINGS FROM RIKEN-BNL RESEARCH CENTER WORKSHOP: PARITY-VIOLATING SPIN ASYMMETRIES AT RHIC

International Nuclear Information System (INIS)

VOGELSANG, W.; PERDEKAMP, M.; SURROW, B.

2007-01-01

as jet and W+charrn final states and spin asymmetries in Z production, were proposed and discussed. All of the talks attracted much interest and initiated active discussions. This was a very successful workshop. It stimulated many discussions and new collaborations. We are grateful to all participants and speakers for coming to the Center, and for their excellent work. The support provided for this workshop by Dr. N. Samios and his RIKEN-BNL Research Center has been magnificent, and we are very grateful for it. We thank Brookhaven National Laboratory and the U.S. Department of Energy for providing the facilities to hold the workshop. Finally, sincere thanks go to Jane Lysik for her efficient work on organizing and running the workshop

Present status of the Riken accelerator research facility (RARF)

International Nuclear Information System (INIS)

Kase, M.; Goto, A.; Kageyama, T.; Yokoyama, I.; Nagase, M.; Kohara, S.; Nakagawa, T.; Inabe, N.; Ikegami, K.; Kamigaito, O.; Kidera, M.; Fujita, J.; Yoneda, A.; Kobayashi, M.; Yano, Y.

1999-01-01

The K540-MeV RIKEN Ring Cyclotron (RRC) celebrated 10 years of successful beam operation in December 1996. The beam intensities have been increased over years to the present levels of about 500 pnA for 135 MeV/nucleon 12 C and of 2000 pnA for 24 MeV/nucleon 40 Ar. The variation of beam has now exceeded one hundred. These beams have been delivered to users in many fields. Improvements are being and will be made to upgrade the present machine to be matched as an injector to the program of the RI beam factory. (authors)

All I Really Need to Know I Learned in Kindergarten: How Dr. Seuss Reinforces Management Concepts and Promotes Community Citizenship

Science.gov (United States)

Comer, Debra R.; Holbrook, Robert L., Jr.

2005-01-01

The authors recommend that management educators add the works of Dr. Seuss to their repertoire of teaching tools. After describing why instructors should use Dr. Seuss's stories to foster understanding of concepts in management and organizational behavior, the authors describe a Seuss-based project at two levels that (a) helps students identify…

Status report on RIKEN Ring Cyclotron

International Nuclear Information System (INIS)

Yano, Y.

1988-01-01

This paper gives a status report on RIKEN Ring Cyclotron (RRC), successfully commissioned on December 16, 1986. The routine operation of RRC began in April, 1987, and was made until March 1988. April and May were devoted to the machine studies, and beams were delivered to the experiments from the end of May. Seven kinds of ion species from carbon to copper were used for the nuclear physics and atomic physics experiments during these one-year runs. High quality beams with transverse emittances less than 10 mm mrad, energy spread of approximately 0.1% and pulse width less than 300 psec were extracted. Since the middle of March, 1988, RRC has been shut down for extending the beam transfer lines and installing the various experimental setups. Next experimental program will start in July, 1988. The initial operational status of RRC is described as well as the running construction program of the new injector, a K70 AVF cyclotron with an external ECR ion source

Spectroscopy on neutron-rich nuclei at RIKEN. Present and future

International Nuclear Information System (INIS)

Sakurai, H.

2003-01-01

Recent studies on nuclear structure by using radioactive isotope beams available at the RIKEN projectile-fragment separator (RIPS) are introduced. Special emphasis is given to experiments selected from the recent programs that highlight studies at N=20-28; on the large deformation of 30 Ne and 34 Mg via the in-beam gamma spectroscopy, and on the particle stability of very neutron-rich nuclei, 34 Ne, 37 Na and 43 Si. The RI Beam Factory (RIBF) project is illustrated through review of such present research activities at RIPS. (author)

Analysis Of Liquid Waste Management At Dr. Mohammad Hoesin Palembang's Hospital

OpenAIRE

Hartini, Resi; Hasyim, Hamzah; Ainy, Asmaripa

2011-01-01

Background : The hospital is an institution that service activities of preventive, curative, rehabilitative and promotive health. These activities produce solid, liquid, and gas waste. Liquid waste can cause diseases and environment pollution so need special waste management. Dr. Mohammad Hoesin Palembang's Hospital producea lot of liquid waste. Method : This study is a descriptive research with qualitative approach. Sources of information consist four informants. The research are using dept...

QUARKONIUM PRODUCTION IN RELATIVISTIC NUCLEAR COLLISIONS. PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP, VOLUME 12

Energy Technology Data Exchange (ETDEWEB)

KHARZEEV,D.

1999-04-20

The RIKEN-BNL Workshop on Quarkonium Production in Relativistic Nuclear Collisions was held September 28--October 2, 1998, at Brookhaven National Laboratory. The Workshop brought together about 50 invited participants from around the world and a number of Brookhaven physicists from both particle and nuclear physics communities.

Quarkonium production in relativistic nuclear collisions. Proceedings of Riken BNL Research Center Workshop,Volume 12

International Nuclear Information System (INIS)

Kharzeev, D.

1999-01-01

The RIKEN-BNL Workshop on Quarkonium Production in Relativistic Nuclear Collisions was held September 28--October 2, 1998, at Brookhaven National Laboratory. The Workshop brought together about 50 invited participants from around the world and a number of Brookhaven physicists from both particle and nuclear physics communities

Dr. Yu Wang, Director, Natural Science Division, National Science Council, Taiwan

CERN Document Server

Patrice Loïez

2001-01-01

Photo 01: L. to r.: Dr. Philippe Bloch, CERN CMS ECAL Deputy Project Manager, Dr. Yu Wang, Dr. Etiennette Auffray, CERN, responsible of the CERN ECAL Regional Centre. Photo 02: L. to r.: Dr. Yu Wang, Dr. Philippe Bloch, Dr. Apollo GO, National Central University, Taiwan, Dr. Etiennette Auffray.

Production of intense beams of highly charged heavy ions from RIKEN 18 GHz ECRIS and liquid He free SC-ECRIS

International Nuclear Information System (INIS)

Nakagawa, T.; Kidera, M.; Kageyama, T.; Kase, M.; Yano, Y.; Higurashi, Y.; Kurita, T.; Imanaka, M.

2001-01-01

We have constructed the high performance ECRISs for RIKEN RI Beam factory project and successfully produced intense beams of highly charged heavy ions. RIKEN 18 GHz ECRIS can especially produce intense beams of medium charge states of heavy ions (1.3 mA of Ar 8+ , 200 eμA of Xe 20+ ) by applying the various techniques, e.g., Al cylinder method, biased electrode method, optimization of the plasma electrode position. Very recently, we successfully produced intense beams of highly charged heavy ions (10 eμA of Xe 30+ , 1 eμA of Xe 36+ ) from the Liquid He free SC-ECRIS with operational frequency of 14 GHz

Santhanam, Dr Vaidyanathaswamy

Indian Academy of Sciences (India)

Elected: 1974 Section: Plant Sciences. Santhanam, Dr Vaidyanathaswamy Ph.D. (Madras). Date of birth: 31 July 1925. Specialization: Plant Breeding & Genetics, Research Management and Cotton Development Address: 'Shri Abhirami', 107, Venkataswamy Road West, R S Puram Post, Coimbatore 641 002, T.N.. Contact:

Proceedings of RIKEN BNL Research Center Workshop: Thermal Photons and Dileptons in Heavy-Ion Collisions. Volume 119

Energy Technology Data Exchange (ETDEWEB)

David, G. [Brookhaven National Laboratory (BNL), Upton, NY (United States); Rapp, R. [Brookhaven National Laboratory (BNL), Upton, NY (United States); Ruan, L. [Brookhaven National Laboratory (BNL), Upton, NY (United States); Yee, H-U. [Brookhaven National Laboratory (BNL), Upton, NY (United States)

2014-09-11

The RIKEN BNL Research Center (RBRC) was established in April 1997 at Brookhaven National Laboratory. It is funded by the ''Rikagaku Kenkyusho'' (RIKEN, The Institute of Physical and Chemical Research) of Japan and the U. S. Department of Energy’s Office of Science. The RBRC is dedicated to the study of strong interactions, including spin physics, lattice QCD, and RHIC physics through the nurturing of a new generation of young physicists. The RBRC has theory, lattice gauge computing and experimental components. It is presently exploring the possibility of an astrophysics component being added to the program. The primary theme for this workshop related to sharing the latest experimental and theoretical developments in area of low transverse momentum (p_T) dielectron and photons. All the presentations given at the workshop are included in this proceedings, primarily as PowerPoint presentations.

RIKEN accelerator progress report, vol. 18

International Nuclear Information System (INIS)

Ambe, S.; Awaya, Y.; Gono, Y.; Inamura, T.; Kamitsubo, H.; Kitayama, S.; Odera, M.; Watanabe, T.; Yagi, E.

1985-06-01

The collaborative research using the 160 cm cyclotron and the variable frequency, heavy ion linear accelerator (RILAC) has been extensively performed in this year. In addition, an electrostatic accelerator (TANDETRON) of IMV and an ion implanter of 250 kV were dedicated to the collaborative research. During the past one year, the cyclotron was in good condition, and a new gas feed system was developed as the cyclotron ion source. The operation of the RILAC in a full 17 - 45 MHz range was realized. The TANDETRON has been steadily operated. The nuclear spectroscopy and reaction mechanism for heavy ion collision were studied. Instrument development was continued for the purpose of building the new experimental equipment for SSC. Experiments were carried out on the beam foil spectroscopy and atomic collision measuring ultra-violet ray, x-ray, Auger electrons and recoil ions. Moessbauer spectroscopy and perturbed angular correlation studies were continued. The creep and helium bubble formation in fusion reactor materials by bombarding with alpha particles and protons were studied in cooperation with the National Research Institute for Metals. The construction of the Riken Ring Cyclotron progressed. (Kako, I.)

Perturbative QCD as a probe of hadron structure: Volume 2. Proceedings of RIKEN BNL Research Center workshop

International Nuclear Information System (INIS)

1997-01-01

The workshop brought together about thirty invited participants from around the world, and an almost equal number of Brookhaven users and staff, to discuss recent developments and future prospects for hadronic strong interaction studies at high energy, particularly relating to the RHIC project at Brookhaven. RIKEN and Brookhaven have long traditions in and commitments to the study of the strong interactions, and the advent of the RHIC collider will open new opportunities both for relativistic heavy ion and polarized proton-proton studies. Activities at the RIKEN BNL Research Center are intended to focus on physics opportunities stimulated by this new facility. Thus, one of the purposes of the center is to provide a forum where workers in the field can gather to share and develop their ideas in a stimulating environment. The purpose of the workshop was both to delineate theoretical problems and stimulate collaborations to address them. The workshop focused primarily, but not exclusively, on spin and small-x physics

PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP, VOLUME 65, RHIC SPIN COLLABORATION MEETINGS XXVII, XXVIII, and XXX

International Nuclear Information System (INIS)

OGAWA, A.

2004-01-01

The RIKEN BNL Research Center (RSRC) was established in April 1997 at Brookhaven National Laboratory. It is funded by the 'Rikagaku Kenkyusho' (RIKEN, The Institute of Physical and Chemical Research) of Japan. The Center is dedicated to the study of strong interactions, including spin physics, lattice QCD, and RHIC physics through the nurturing of a new generation of young physicists. The RBRC has both a theory and experimental component. At present the theoretical group has 4 Fellows and 3 Research Associates as well as 11 RHIC Physics/University Fellows (academic year 2003-2004). To date there are approximately 30 graduates from the program of which 13 have attained tenure positions at major institutions worldwide. The experimental group is smaller and has 2 Fellows and 3 RHIC Physics/University Fellows and 3 Research Associates, and historically 6 individuals have attained permanent positions. Beginning in 2001 a new RIKEN Spin Program (RSP) category was implemented at RBRC. These appointments are joint positions of RBRC and RIKEN and include the following positions in theory and experiment: RSP Researchers, RSP Research Associates, and Young Researchers, who are mentored by senior RBRC Scientists, A number of RIKEN Jr. Research Associates and Visiting Scientists also contribute to the physics program at the Center. RBRC has an active workshop program on strong interaction physics with each workshop focused on a specific physics problem. Each workshop speaker is encouraged to select a few of the most important transparencies from his or her presentation, accompanied by a page of explanation. This material is collected at the end of the workshop by the organizer to form proceedings, which can therefore be available within a short time. To date there are sixty nine proceedings volumes available. The construction of a 0.6 teraflops parallel processor, dedicated to lattice QCD, begun at the Center on February 19, 1998, was completed on August 28, 1998 and is still

Implications of the recent D-T μCF experiments at RIKEN-RAL and near-future directions

International Nuclear Information System (INIS)

Nagamine, K.; Matsuzaki, T.; Ishida, K.; Nakamura, S.N.; Kawamura, N.

1999-01-01

The paper describes physics implications obtained through the recent experimental results on D-T μCF at RIKEN-RAL. Smaller sticking and larger cycling rates in solid/liquid D-T mixture than the theoretical predictions were observed, suggesting needs of further theoretical understandings. Some possible future directions in D-T μCF experiments are also described

PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP: VOLUME 69 RBRC SCIENTIFIC REVIEW COMMITTEE MEETING

International Nuclear Information System (INIS)

SAMIOS, N.P.

2005-01-01

The RIKEN BNL Research Center (RSRC) was established in April 1997 at Brookhaven National Laboratory. It is funded by the 'Rikagaku Kenkyusho' (RIKEN, The Institute of Physical and Chemical Research) of Japan. The Center is dedicated to the study of strong interactions, including spin physics, lattice QCD, and RHIC physics through the nurturing of a new generation of young physicists. The RBRC has both a theory and experimental component. At present the theoretical group has 4 Fellows and 3 Research Associates as well as 11 RHIC Physics/University Fellows (academic year 2003-2004). To date there are approximately 30 graduates from the program of which 13 have attained tenure positions at major institutions worldwide. The experimental group is smaller and has 2 Fellows and 3 RHIC Physics/University Fellows and 3 Research Associates, and historically 6 individuals have attained permanent positions. Beginning in 2001 a new RIKEN Spin Program (RSP) category was implemented at RBRC. These appointments are joint positions of RBRC and RIKEN and include the following positions in theory and experiment: RSP Researchers, RSP Research Associates, and Young Researchers, who are mentored by senior RBRC Scientists, A number of RIKEN Jr. Research Associates and Visiting Scientists also contribute to the physics program at the Center. RBRC has an active workshop program on strong interaction physics with each workshop focused on a specific physics problem. Each workshop speaker is encouraged to select a few of the most important transparencies from his or her presentation, accompanied by a page of explanation. This material is collected at the end of the workshop by the organizer to form proceedings, which can therefore be available within a short time. To date there are sixty nine proceedings volumes available. The construction of a 0.6 teraflops parallel processor, dedicated to lattice QCD, begun at the Center on February 19, 1998, was completed on August 28, 1998 and is still

Waste Management Plan for the Drilling Within the Chromium Plume West of 100-D/DR Reactors

International Nuclear Information System (INIS)

R.E. Peterson

1997-01-01

This waste management plan provides guidance for managing drilling spoils generated during the installation of groundwater wells in the 100-D/DR Area, which is part of the 100-HR-3 Operable Unit. The wells are being installed to meet two objectives: (1) better define the nature and extent of a previously identified chromium plume in the area, and (2) act as groundwater extraction wells if the contamination warrants

Proceedings of RIKEN BNL Research Center Workshop: The Approach to Equilibrium in Strongly Interacting Matter. Volume 118

Energy Technology Data Exchange (ETDEWEB)

Liao, J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Venugopalan, R. [Brookhaven National Lab. (BNL), Upton, NY (United States); Berges, J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Blaizot, J. -P. [Brookhaven National Lab. (BNL), Upton, NY (United States); Gelis, F. [Brookhaven National Lab. (BNL), Upton, NY (United States)

2014-04-09

The RIKEN BNL Research Center (RBRC) was established in April 1997 at Brookhaven National Laboratory*. It is funded by the ''Rikagaku Kenkyusho'' (RIKEN, The Institute of Physical and Chemical Research) of Japan and the U. S. Department of Energy’s Office of Science. The RBRC is dedicated to the study of strong interactions, including spin physics, lattice QCD, and RHIC physics through the nurturing of a new generation of young physicists. The RBRC has theory, lattice gauge computing and experimental components. It is presently exploring the possibility of an astrophysics component being added to the program. The purpose of this Workshop is to critically review the recent progress on the theory and phenomenology of early time dynamics in relativistic heavy ion collisions from RHIC to LHC energies, to examine the various approaches on thermalization and existing issues, and to formulate new research efforts for the future. Topics slated to be covered include Experimental evidence for equilibration/isotropization, comparison of various approaches, dependence on the initial conditions and couplings, and turbulent cascades and Bose-Einstein condensation.

China's Investment Leade Dr, Alyce Su

Institute of Scientific and Technical Information of China (English)

2010-01-01

@@ I. Professional Background Dr. Alyce Su specializes in investment managemeng, managing portfolios consisted of investment opportunities originated from China's growth and internationalization, both'outbound and inbound.

Leadership Management Personnel in Primary Education Subsystem. EU. “Dr. Amilcar Fonseca”

Directory of Open Access Journals (Sweden)

Yajaira Esperanza Araujo Araujo

2016-11-01

Full Text Available The purpose of this research is to determine the leadership of the management staff in the subsystem of primary education Educational Unit "Dr. Amílcar Fonseca "County Candelaria Trujillo state. The study was descriptive type that helped deepen understanding, knowledge and variable information posed: leadership, using a field design because the information was obtained on the same site the facts; ie, where the school was delimited research. In relation to the sample population worked with 43 teachers working in the institution to which they applied an instrument type questionnaire composed of multiple alternative 36 items and its validation was granted three (03 experts who verified the compliance methodological criteria required for that purpose. While reliability was 0.98 using Cronbach alpha coefficient. The results showed that on campus management does not use different types of leadership; It was concluded that the relevant time current educational managers must combine different paradigms in his leadership.

Report from the Third Annual Symposium of the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology.

Science.gov (United States)

Brunschweiger, Andreas

2014-08-15

The third Annual Symposium of the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology was held at Ringberg castle, May 21-24, 2014. At this meeting 45 scientists from Japan and Germany presented the latest results from their research spanning a broad range of topics in chemical biology and glycobiology.

Ghosh, Dr Pushpito Kumar

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 2010 Section: Chemistry. Ghosh, Dr Pushpito Kumar Ph.D. (Princeton). Date of birth: 29 May 1954. Specialization: Processes Research, Water Purification, Renewable Energy, R&D Management Address: A-604, Punit Park, Plot No. 182/C, Sector 17, Merol, Navi Mumbai 400 706, ...

Results of RIKEN superconducting electron cyclotron resonance ion source with 28 GHz.

Science.gov (United States)

Higurashi, Y; Ohnishi, J; Nakagawa, T; Haba, H; Tamura, M; Aihara, T; Fujimaki, M; Komiyama, M; Uchiyama, A; Kamigaito, O

2012-02-01

We measured the beam intensity of highly charged heavy ions and x-ray heat load for RIKEN superconducting electron cyclotron resonance ion source with 28 GHz microwaves under the various conditions. The beam intensity of Xe(20+) became maximum at B(min) ∼ 0.65 T, which was ∼65% of the magnetic field strength of electron cyclotron resonance (B(ECR)) for 28 GHz microwaves. We observed that the heat load of x-ray increased with decreasing gas pressure and field gradient at resonance zone. It seems that the beam intensity of highly charged heavy ions with 28 GHz is higher than that with 18 GHz at same RF power.

RIKEN RI Beam Factory and recent research activities

International Nuclear Information System (INIS)

Ueno, H.

2014-01-01

RIKEN has started the operation of the new facility for the Radioactive-Isotope Beam Factory (RIBF) project since 2006. In this project, intense primary beams are delivered at the energy E/A = 345 MeV over the whole range of the atomic number under the cyclotron-cascade acceleration scheme. The current, stability and sustainability in beam delivery have been increased significantly by recent improvement of the accelerator system. A high-current primary beam is then used to produce radioactive-isotope beams at the world's highest current utilizing the superconducting in-flight RI separator BigRIPS. Following the BigRIPS separator, several large-scale experimental key devices have been / will be installed, in order to fully capitalize the RIBF project. Owing to these progresses, nuclear structure information on far-unstable nuclei, which cannot be obtained by conventional technology, are now capable of being measured. Furthermore, in addition to such BigRIPS-related devices, other original experimental devices have been also newly installed at the lower energy experimental sites. Unique research opportunities are now available at the RIBF facility. (author)

Accelerators in RIKEN from 1910's to the present (Part Three)

International Nuclear Information System (INIS)

Kamitsubo, Hiromichi

2006-01-01

The nuclear experiment laboratory was established by H. Nagaoka, Y. Nishina and S. Nishikawa in 1931. A cyclotron using Pullsen arc generator was built at the start. The effects of neutron on mouse and paraffin were researched by the cyclotron. This small cyclotron realized stabilization of the magnetic field at first in the world. Outline of small cyclotron and large cyclotron, and details of building of two cyclotrons are described. The large cyclotron was completed in 1943, and nuclear experiments using accelerated deuteron were begun. However, the large and small cyclotrons were destructed by USA army depended on the finish of the Second World War in 1945. After that, the heavy ion cyclotron was constructed by RIKEN in 1962. (S.Y.)

Detector system of the first focal plane of the spectrometer SMART at RIKEN

International Nuclear Information System (INIS)

Okamura, H.; Izshida, S.; Sakamoto, N.; Otsu, H.; Uesaka, T.; Wakasa, T.; Satou, Y.; Sakai, H.; Ichihara, T.

1998-01-01

A detector system of the first focal plane of SMART, the 135 MeV/u high-resolution spectrometer at RIKEN accelerator research facility, is described. It consists of a pair of multi-wire drift chambers and a trigger scintillator hodoscope contained in a He-filled detector box. A major subject using this system is the measurement of the (d, 2 He) reaction making the most of its large angular and momentum acceptances. Without seriously sacrificing the detection efficiency, reasonably good energy and angular resolutions for 2 He, 460 keV and 9 mrad (FWHM), respectively, have been achieved after optimizing the optics property of the spectrometer. (orig.)

Dr. Praveen Chaudhari named director of Brookhaven National Laboratory

CERN Multimedia

2003-01-01

"Brookhaven Science Associates announced today the selection of Dr. Praveen Chaudhari as Director of the U.S. Department of Energy's Brookhaven National Laboratory. Dr. Chaudhari, who will begin his new duties on April 1, joins Brookhaven Lab after 36 years of distinguished service at IBM as a scientist and senior manager of research" (1 page).

Shielding design of RIKEN RI Beam Factory

Energy Technology Data Exchange (ETDEWEB)

Uwamino, Yoshitomo; Fukunishi, Nobuhisa [Institute of Physical and Chemical Research, Wako, Saitama (Japan); Oishi, Koji [Shimizu Corp., Tokyo (Japan)

2000-03-01

Construction of the RIKEN RI Beam Factory is started, and the phase 1 will be finished by the end of March 2003. Two ring cyclotrons including one superconducting machine and two Big RIPSs will be constructed in the phase 1. Heavy ions of proton to uranium will be accelerated up to 400 MeV/u (A<40) and 150 MeV/u for uranium at an intensity of 10{sup 13} pps. Neutron production by the 400 MeV/u {sup 20}Ne beam was measured at HIMAC of NIRS and it was used for the source term of the shielding calculations. The deep penetration of high-energy neutrons was calculated by using the ANISN code with the DLC-119/HILO86R group constants and also by using the HETC code. The ANISN results were modified by using the HETC results and the shielding experiment at ISIS, and they were fitted by a simple formula for practical use. High-energy neutron penetrations of slantwise injection and the reflection probabilities of iron slab were calculated with the HETC code, and these results were used for the estimation of the thickness for the iron local shielding of Big RIPSs. Induced radioactivity in the air, accelerator components and the building, and the skyshine effect were also estimated. (author)

Beam orbit in the central region of the RIKEN AVF cyclotron

International Nuclear Information System (INIS)

Toprek, D.; Subotic, K.; Goto, A.; Yano, Y.

1998-01-01

This paper describes the modification design of the central region for h=2 mode of acceleration in the RIKEN AVF cyclotron. The central region is equipped with an axial injection system. The spiral type inflector is used for axial injection. The electric field distribution in the inflector and in four acceleration gaps has been numerically calculated from an electric potential map produced by the program RELAX3D. The magnetic field is measured. The geometry of the central region has been tested with the computations of orbits carried out by means of the computer code CYCLONE. The optical properties of the spiral inflector and the central region are studied by using the program CASINO and CYCLONE, respectively. We have also made an effort to minimize the inflector fringe field using the RELAX3D program. (author)

Construction of a beam rebuncher for RIKEN RI-beam factory

International Nuclear Information System (INIS)

Aoki, T.; Stingelin, L.; Kamigaito, O.; Sakamoto, N.; Fukunishi, N.; Yokouchi, S.; Maie, T.; Kase, M.; Goto, A.; Yano, Y.

2008-01-01

A beam rebuncher for the RIKEN radioactive-isotope beam factory project has been constructed and is placed in a long beam line between the first two ring cyclotrons in the accelerator cascade. The rebuncher resonator, having four rf gaps in it, operates at a fixed frequency of 109.5 MHz for the longitudinal focusing of heavy ion beams at 11.0MeV/u. To reduce the sparking problem in the rf gaps, a new type of H-mode resonator has been adopted, where the distribution of the gap voltage is well equalized. In fact, the ratio of the gap voltages is about 1.26, whereas those of the interdigital-H (IH)- and crossed-bar-H (CH)-mode structures are larger than 2.0. The total gap voltage, which is defined as the sum of the four gap voltages, has reached 495 kV at a power consumption of 4.7 kW

Dr. Packianathan “Chella” Chelladurai: An Eminent Scholar in Sport Management. [Dr. Packianathan “Chella” Chelladurai: Un eminente académico en gestión deportiva].

Directory of Open Access Journals (Sweden)

Donna L. Pastore

2014-01-01

Full Text Available Dr. Packianathan “Chella” Chelladurai has a long and distinguished career in sport management and is a recognized scholar of management science. Chella received his Bachelor’s and Doctor of Physical Education degrees from the University of Madras, India. He was a member of the All Star Basketball Team of India and coached several basketball teams. Chella left India to pursue graduate studies in Canada. He received a Master’s degree in physical education from the University of Western Ontario, and an additional Master’s degree from the University of Waterloo. Chella further pursued his Ph.D in management science as well from the University of Waterloo. Chella served on the faculty of the University of Western Ontario from 1971 to 1991. He then joined the faculty at The Ohio State University from 1991 until his retirement in 2012. Currently, Chella is a Distinguished Professor of Sport Management at Troy University.

2700-IJBCS-Article-Dr Matar Seck

African Journals Online (AJOL)

hp

of Maytenus senegalensis in the management of sickle cell disease. © 2016 International ... En plus de l'anémie, la vaso-occlusion, résultant de la ... crises de douleur, de la fièvre et des douleurs ... vaso-occlusives dans la drépanocytose. Ces.

Gaia DR1 documentation Chapter 6: Variability

Science.gov (United States)

Eyer, L.; Rimoldini, L.; Guy, L.; Holl, B.; Clementini, G.; Cuypers, J.; Mowlavi, N.; Lecoeur-Taïbi, I.; De Ridder, J.; Charnas, J.; Nienartowicz, K.

2017-12-01

This chapter describes the photometric variability processing of the Gaia DR1 data. Coordination Unit 7 is responsible for the variability analysis of over a billion celestial sources. In particular the definition, design, development, validation and provision of a software package for the data processing of photometrically variable objects. Data Processing Centre Geneva (DPCG) responsibilities cover all issues related to the computational part of the CU7 analysis. These span: hardware provisioning, including selection, deployment and optimisation of suitable hardware, choosing and developing software architecture, defining data and scientific workflows as well as operational activities such as configuration management, data import, time series reconstruction, storage and processing handling, visualisation and data export. CU7/DPCG is also responsible for interaction with other DPCs and CUs, software and programming training for the CU7 members, scientific software quality control and management of software and data lifecycle. Details about the specific data treatment steps of the Gaia DR1 data products are found in Eyer et al. (2017) and are not repeated here. The variability content of the Gaia DR1 focusses on a subsample of Cepheids and RR Lyrae stars around the South ecliptic pole, showcasing the performance of the Gaia photometry with respect to variable objects.

Dr Luigi Orlando, Dr Sergio Ceccuzzi, Dr. Armando Sbrana, Europa Metalli, Italy, Dr Albert Scherger, Member of KM Europa Metal AG, Osnabr ck, Germany, Prof. Filippo Menzinger, Scientific Attaché, Permanent Mission of Italy in Geneva

CERN Multimedia

Patrice Loïez

2001-01-01

Photo 01: Dr Lyn Evans and Dr Luigi Orlando Photo 04: L. to r.: Dr Lyn Evans, Dr Luigi Orlando, Prof. Luciano Maiani and Prof. Filippo Menzinger Photo 06: L. to r.: Prof. Philippo Menzinger, Dr Armando Sbrana, Prof. Luciano Maiani, Dr Albert Scherger, Dr Lyn Evans, Dr Luigi Orlando, Dr Sergio Ceccuzzi, visiting the LHC superconducting magnet test hall, SM18

Beam Orbit Simulation In The Central Region Of The Riken Avf Cyclotron

International Nuclear Information System (INIS)

Toprek, D; Subotic, K.; Goto, A.; Yano, Y.

1998-01-01

This paper describes the modification design of the central region for A = 2 mode of acceleration in the Riken Avf cyclotron. The central region is equipped with an axial injection system. The spiral type inflector is used for axial injection. The electric field distribution in the inflector and in four acceleration gaps has been numerically calculated from an electric potential map produced by the program RELAX3D. The magnetic field is measured. The geometry of the central region has been tested with the computations of orbits carried out by means of the computer code CYCLONE. The optical properties of the spiral inflector and the central region are studied by using the program CASINO and CYCLONE, respectively. We have also made an effort to minimize the inflector fringe field using the RELAX3D program. (authors)

Beam orbit simulation in the central region of the RIKEN AVF cyclotron

International Nuclear Information System (INIS)

Toprek, Dragan; Goto, Akira; Yano, Yasushige

1997-01-01

This paper describes the modification design of the central region for h = 2 mode of acceleration in the RIKEN AVF cyclotron. The central region is equipped with an axial injection system. The spiral type inflector is used for axial injection. The electric field distribution in the inflector and in four acceleration gaps has been numerically calculated from an electric potential map produced by the program RELAX3D. The magnetic field is measured. The geometry of the central region has been tested with the computations of orbits carried out by means of the computer code CYCLONE. The optical properties of the spiral inflector and the central region are studied by using the program CASINO and CYCLONE, respectively. We have also made an effort to minimize the inflector fringe field using the RELAX3D program. (author)

Proceedings of RIKEN BNL Research Center Workshop, RHIC Spin Physics V, Volume 32, February 21, 2001

International Nuclear Information System (INIS)

BUNCE, G.; SAITO, N.; VIGDOR, S.; ROSER, T.; SPINKA, H.; ENYO, H.; BLAND, L.C.; GURYN, W.

2001-01-01

The RIKEN BNL Research Center (RBRC) was established in April 1997 at Brookhaven National Laboratory. It is funded by the ''Rikagaku Kenkysho'' (RIKEN, The Institute of Physical and Chemical Research) of Japan. The Center is dedicated to the study of strong interactions, including spin physics, lattice QCD and RHIC physics through the nurturing of a new generation of young physicists. During the fast year, the Center had only a Theory Group. In the second year, an Experimental Group was also established at the Center. At present, there are seven Fellows and nine post dots in these two groups. During the third year, we started a new Tenure Track Strong Interaction Theory RHIC Physics Fellow Program, with six positions in the academic year 1999-2000; this program will increase to include eleven theorists in the next academic year, and, in the year after, also be extended to experimental physics. In addition, the Center has an active workshop program on strong interaction physics, about ten workshops a year, with each workshop focused on a specific physics problem. Each workshop speaker is encouraged to select few of the most important transparencies from his or her presentation, accompanied by a page of explanation. This material is collected at the end of the workshop by the organizer to form proceedings, which can therefore be available within a short time. The construction of a 0.6 teraflop parallel processor, which was begun at the Center on February 19, 1998, was completed on August 28, 1998

Dræb, dræb, dræb! Nej ... liiiige et øjeblik: De machiavelliske følelser i Game of Thrones

DEFF Research Database (Denmark)

Schubart, Rikke

2013-01-01

Blogindlæg om Machiavelliske følelser i HBO tv-serien Game of Thrones: "Dræb, dræb, dræb! Nej ... liiiige et øjeblik: De machiavelliske følelser i Game of Thrones"......Blogindlæg om Machiavelliske følelser i HBO tv-serien Game of Thrones: "Dræb, dræb, dræb! Nej ... liiiige et øjeblik: De machiavelliske følelser i Game of Thrones"...

Status and results from the decay spectroscopy project EURICA (Euroball-RIKEN cluster array)

Energy Technology Data Exchange (ETDEWEB)

Söderström, P.-A., E-mail: pasoder@ribf.riken.jp; Doornenbal, P.; Nishimura, S.; Baba, H.; Isobe, T.; Kiss, G. [RIKEN Nishina Center, 2-1 Hirosawa, Wako-shi, Saitama 351-0198 (Japan); Lorusso, G. [RIKEN Nishina Center, 2-1 Hirosawa, Wako-shi, Saitama 351-0198 (Japan); National Physical Laboratory, Teddington, Middlesex, TW11 0LW (United Kingdom); Wu, J. [RIKEN Nishina Center, 2-1 Hirosawa, Wako-shi, Saitama 351-0198 (Japan); School of Physics, Peking University, Beijing 100871 (China); Xu, Z. Y. [Department of Physics, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); KU Leuven, Instituut voor Kern-en Stralingsfysica, 3001 Leuven (Belgium); Benzoni, G. [Istituto Nazionale di Fisica Nucleare, Sezione di Milano, Via Celoria 16, 20133 Milano (Italy); Browne, F. [RIKEN Nishina Center, 2-1 Hirosawa, Wako-shi, Saitama 351-0198 (Japan); School of Computing, Engineering and Mathematics, University of Brighton, Brighton BN2 4JG (United Kingdom); Gey, G. [RIKEN Nishina Center, 2-1 Hirosawa, Wako-shi, Saitama 351-0198 (Japan); LPSC, Université Grenoble-Alpes, CNRS/IN2P3, F-38026 Grenoble Cedex (France); ILL, 38042 Grenoble Cedex (France); Research Center for Nuclear Physics (RCNP), Osaka University, Ibaraki, Osaka 567-0047 (Japan); Jungclaus, A. [Instituto de Estructura de la Materia, CSIC, E-28006 Madrid (Spain); Kojouharov, I.; Kurz, N.; Schaffner, H. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291 Darmstadt (Germany); Lubos, D. [RIKEN Nishina Center, 2-1 Hirosawa, Wako-shi, Saitama 351-0198 (Japan); Physik Department E12, Technische Universität München, D-85748 Garching (Germany); Moschner, K. [RIKEN Nishina Center, 2-1 Hirosawa, Wako-shi, Saitama 351-0198 (Japan); IKP, University of Cologne, D-50937 Cologne (Germany); and others

2016-07-07

β- and isomer-decay spectroscopy are sensitive probes of nuclear structure, and are often the only techniques capable of providing data for exotic nuclei that are produced with very low rates. Decay properties of exotic nuclei are also essential to model astrophysical events responsible for the evolution of the universe such as the rp- and r-processes. The EURICA project (EUROBALL RIKEN Cluster Array) has been launched in 2012 with the goal of performing spectroscopy of very exotic nuclei. Since 2012, five experimental campaigns have been successfully completed using fragmentation of {sup 124}Xe beam and in-flight-fission of {sup 238}U beam. In these proceedings we will introduce the experimental setup and highlight some key recent results around {sup 78}Ni, {sup 132}Sn, and {sup 110}Zn published during 2014 and 2015.

DR6 as a diagnostic and predictive biomarker in adult sarcoma.

Directory of Open Access Journals (Sweden)

Kun Yang

Full Text Available The Death Receptor 6 (DR6 protein is elevated in the serum of ovarian cancer patients. We tested DR6 serum protein levels as a diagnostic/predictive biomarker in several epithelial tumors and sarcomas.DR6 gene expression profiles were screened in publically available arrays of solid tumors. A quantitative immunofluorescent western blot analysis was developed to test the serum of healthy controls and patients with sarcoma, uterine carcinosarcoma, bladder, liver, and pancreatic carcinomas. Change in DR6 serum levels was used to assay the ability of DR6 to predict the response to therapy of sarcoma patients.DR6 mRNA is highly expressed in all tumor types assayed. Western blot analysis of serum DR6 protein demonstrated high reproducibility (r = 0.97. Compared to healthy donor controls, DR6 serum levels were not elevated in patients with uterine carcinosarcoma, bladder, liver, or pancreatic cancers. Serum DR6 protein levels from adult sarcoma patients were significantly elevated (p<0.001. This was most evident for patients with synovial sarcoma. Change in serum DR6 levels during therapy correlated with clinical benefit from therapy (sensitivity 75%, and positive predictive value 87%.DR6 may be a clinically useful diagnostic and predictive serum biomarker for some adult sarcoma subtypes.Diagnosis of sarcoma can be difficult and can lead to improper management of these cancers. DR6 serum protein may be a tool to aid in the diagnosis of some sarcomatous tumors to improve treatment planning. For patients with advanced disease, rising DR6 levels predict non-response to therapy and may expedite therapeutic decision making and reduce reliance on radiologic imaging.

An EMD-ANN based prediction methodology for DR driven smart household load demand

NARCIS (Netherlands)

Tascikaraoglu, A.; Paterakis, N.G.; Catalaõ, J.P.S.; Erdinç, O.; Bakirtzis, A.G.

2015-01-01

This study proposes a model for the prediction of smart household load demand influenced by a dynamic pricing demand response (DR) program. Price-based DR programs have a considerable impact on household demand pattern due to the expected choice of customers or their home energy management systems

Time-stamping system for nuclear physics experiments at RIKEN RIBF

International Nuclear Information System (INIS)

Baba, H.; Ichihara, T.; Ohnishi, T.; Takeuchi, S.; Yoshida, K.; Watanabe, Y.; Ota, S.; Shimoura, S.; Yoshinaga, K.

2015-01-01

A time-stamping system for nuclear physics experiments has been introduced at the RIKEN Radioactive Isotope Beam Factory. Individual trigger signals can be applied for separate data acquisition (DAQ) systems. After the measurements are complete, separately taken data are merged based on the time-stamp information. In a typical experiment, coincidence trigger signals are formed from multiple detectors to take desired events only. The time-stamping system allows the use of minimum bias triggers. Since coincidence conditions are given by software, a variety of physics events can be flexibly identified. The live time for a DAQ system is important when attempting to determine reaction cross-sections. However, the combined live time for separate DAQ systems is not clearly known because it depends not only on the DAQ dead time but also on the coincidence conditions. Using the proposed time-stamping system, all trigger timings can be acquired, so that the combined live time can be easily determined. The combined live time is also estimated using Monte Carlo simulations, and the results are compared with the directly measured values in order to assess the accuracy of the simulation

Enhancement of Ar sup 8 sup + ion beam intensity from RIKEN 18 GHz electron cyclotron resonance ion source by optimizing the magnetic field configuration

CERN Document Server

Higurashi, Y; Kidera, M; Kase, M; Yano, Y; Aihara, T

2003-01-01

We successfully produced a 1.55 emA Ar sup 8 sup + ion beam using the RIKEN 18 GHz electron cyclotron resonance ion source at a microwave power of 700 W. To produce such an intense beam, we optimized the minimum magnetic field of mirror magnetic field and plasma electrode position. (author)

105-DR large sodium fire facility closure Plan. Revision 2

International Nuclear Information System (INIS)

Ruck, F.A. III.

1995-03-01

The 105-DR Large Sodium Fire Facility (LSFF), which was operated 1972-1986, was a research laboratory that occupied the former ventilation supply room on the SW side of the 105-DR Reactor Facility. (The 105-DR defense reactor was shut down in 1964.) LSFF was used to investigate fire and safety aspects of large sodium or other metal alkali fires in the LMFBR facilities; it was also used to store and treat alkali metal waste. This closure plan presents a description of the unit, the history of the waste managed, and the procedures that will be followed to close the LSFF as an Alkali Metal Treatment Facility. No future use of LSFF is expected. It is located within the 100-DR-2 (source) and 100-HR-3 (groundwater) operable units, which will be addressed through the RCRA facility investigation/corrective measures study process

RIKEN 200 kV high current implanter for metal surface modification

International Nuclear Information System (INIS)

Iwaki, M.; Yoshida, K.; Sakudo, N.

1985-01-01

A high current, metal ion implanter was constructed in order to aid the formation of a new metastable surface alloy. This implanter, called a RIKEN 200 kV high current implanter, is a modified Lintott high current machine (Series III), which has the advantages of having its own microwave ion source and an extra target chamber. The microwave discharge ion source without a hot-filament has a comparatively long lifetime because the chloride ions and radicals in a plasma during discharge of metal chlorides might prevent metal to deposit on the inner walls of the discharge chamber by bombarding and chemically cleaning them. An extra target chamber for metal modification is able to control the surface composition by utilizing the sputtering effect of the ion beam during ion implantation. The use of this ion source and the extra target chamber is suggested to be suitable for the production of metallic ions and for the implantation into metals. The case study will be introduced for TI implantation into Fe. (orig.)

Beam orbit simulation in the central region of the RIKEN AVF cyclotron

International Nuclear Information System (INIS)

Toprek, Dragan; Goto, Akira; Yano, Yasushige

1999-01-01

This paper describes the modification design of the central region for h=2 mode of acceleration in the RIKEN AVF cyclotron. we made a small modification to the electrode shape in the central region for optimization of the beam transmission. The central region is equipped with an axial injection system. The spiral type inflector is used for axial injection. The electric field distribution in the inflector and in four acceleration gaps has been numerically calculated from an electric potential map produced by the program RELAX3D. The magnetic field is measured. The geometry of the central region has been tested with the computations of orbits carried out by means of the computer code CYCLONE. The optical properties of the spiral inflector and the central region are studied by using the program CASINO and CYCLONE, respectively. We have also made an effort to minimize the inflector fringe field effects using the RELAX3D program

Beam orbit simulation in the central region of the RIKEN AVF cyclotron

CERN Document Server

Toprek, D; Yano, Y

1999-01-01

This paper describes the modification design of the central region for h=2 mode of acceleration in the RIKEN AVF cyclotron. we made a small modification to the electrode shape in the central region for optimization of the beam transmission. The central region is equipped with an axial injection system. The spiral type inflector is used for axial injection. The electric field distribution in the inflector and in four acceleration gaps has been numerically calculated from an electric potential map produced by the program RELAX3D. The magnetic field is measured. The geometry of the central region has been tested with the computations of orbits carried out by means of the computer code CYCLONE. The optical properties of the spiral inflector and the central region are studied by using the program CASINO and CYCLONE, respectively. We have also made an effort to minimize the inflector fringe field effects using the RELAX3D program.

Measurement of the tensor analyzing powers in the dd→3Hen and dd→3Hp reactions at RIKEN

International Nuclear Information System (INIS)

Ladygin, V.P.; Ladygina, N.B; Sakai, H.; Uesaka, T.

2000-01-01

A new experiment is proposed to measure the angular distribution of the tensor analyzing powers A yy , A xx , and A xz in the dd→ 3 Hen and dd→ 3 Hp reactions using polarized deuteron beam at RIKEN. These polarization observables are sensitive to the spin-momentum distribution of neutron (proton) in 3 He( 3 H) at short distances in the framework of one-nucleon exchange approximation. These measurements will provide new insight into the 3-nucleon system spin structure at distances unreachable at the moment using electromagnetic probes

PRODEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP : HIGH PERFORMANCE COMPUTING WITH QCDOC AND BLUEGENE.

Energy Technology Data Exchange (ETDEWEB)

CHRIST,N.; DAVENPORT,J.; DENG,Y.; GARA,A.; GLIMM,J.; MAWHINNEY,R.; MCFADDEN,E.; PESKIN,A.; PULLEYBLANK,W.

2003-03-11

Staff of Brookhaven National Laboratory, Columbia University, IBM and the RIKEN BNL Research Center organized a one-day workshop held on February 28, 2003 at Brookhaven to promote the following goals: (1) To explore areas other than QCD applications where the QCDOC and BlueGene/L machines can be applied to good advantage, (2) To identify areas where collaboration among the sponsoring institutions can be fruitful, and (3) To expose scientists to the emerging software architecture. This workshop grew out of an informal visit last fall by BNL staff to the IBM Thomas J. Watson Research Center that resulted in a continuing dialog among participants on issues common to these two related supercomputers. The workshop was divided into three sessions, addressing the hardware and software status of each system, prospective applications, and future directions.

Design of a resonator for a flat-top acceleration system in the RIKEN AVF cyclotron

International Nuclear Information System (INIS)

Kohara, Shigeo; Miyazawa, Yoshitoshi; Kamigaito, Osamu; Goto, Akira

1997-01-01

A resonator for a flat-top acceleration system in the RIKEN AVF cyclotron is designed to improve the extraction efficiency and the energy spread of a beam. In order to generate the flat-top accelerating voltage on the dee, an additional resonator or a transmission line is capacitively coupled to the AVF resonator with a coupling capacitor. The flat-top accelerating voltage is obtained by the superimposition of the fundamental frequency and the fifth-harmonic-frequency voltages. Length of the additional resonator is 90 cm and capacitance of the coupling capacitor 30 pF. The frequency range of the AVF resonator is from 12 to 23 MHz. Structure and rf characteristics of the resonator designed for the flat-top acceleration system is described. (author)

High spin isomer beam line at RIKEN

Energy Technology Data Exchange (ETDEWEB)

Kishida, T.; Ideguchi, E.; Wu, H.Y. [Institute of Physical and Chemical Research, Saitama (Japan)] [and others

1996-12-31

Nuclear high spin states have been the subject of extensive experimental and theoretical studies. For the production of high spin states, fusion reactions are usually used. The orbital angular momentum brought in the reaction is changed into the nuclear spin of the compound nucleus. However, the maximum induced angular momentum is limited in this mechanism by the maximum impact parameter of the fusion reaction and by the competition with fission reactions. It is, therefore, difficult to populate very high spin states, and as a result, large {gamma}-detector arrays have been developed in order to detect subtle signals from such very high spin states. The use of high spin isomers in the fusion reactions can break this limitation because the high spin isomers have their intrinsic angular momentum, which can bring the additional angular momentum without increasing the excitation energy. There are two methods to use the high spin isomers for secondary reactions: the use of the high spin isomers as a target and that as a beam. A high spin isomer target has already been developed and used for several experiments. But this method has an inevitable shortcoming that only {open_quotes}long-lived{close_quotes} isomers can be used for a target: {sup 178}Hf{sup m2} (16{sup +}) with a half-life of 31 years in the present case. By developing a high spin isomer beam, the authors can utilize various short-lived isomers with a short half-life around 1 {mu}s. The high spin isomer beam line of RIKEN Accelerator Facility is a unique apparatus in the world which provides a high spin isomer as a secondary beam. The combination of fusion-evaporation reaction and inverse kinematics are used to produce high spin isomer beams; in particular, the adoption of `inverse kinematics` is essential to use short-lived isomers as a beam.

Galande, Dr Sanjeev

Indian Academy of Sciences (India)

Elected: 2010 Section: General Biology. Galande, Dr Sanjeev Ph.D. (IISc). Date of birth: 20 September 1967. Specialization: Epigenetics, Chromatin Biology, Gene Regulation, Genomics and Proteomics Address: Centre for Excellence in Epigenetics, Indian Institute of Science Education, & Research, Dr Homi Bhabha Road, ...

Decommissioning of DR 2. Experiences learnt from the completion

International Nuclear Information System (INIS)

Strufe, N.

2009-10-01

The report describes experiences gathered from the decommissioning of DR 2. The experiences encompasses planning and management of the project, methods of accomplishment, and various materials categories. Additionally, the report describes the experience with specific tools used in the project

Gaia DR2 documentation

Science.gov (United States)

van Leeuwen, F.; de Bruijne, J. H. J.; Arenou, F.; Bakker, J.; Blomme, R.; Busso, G.; Cacciari, C.; Castañeda, J.; Cellino, A.; Clotet, M.; Comoretto, G.; Eyer, L.; González-Núñez, J.; Guy, L.; Hambly, N.; Hobbs, D.; van Leeuwen, M.; Luri, X.; Manteiga, M.; Pourbaix, D.; Roegiers, T.; Salgado, J.; Sartoretti, P.; Tanga, P.; Ulla, A.; Utrilla Molina, E.; Abreu, A.; Altmann, M.; Andrae, R.; Antoja, T.; Audard, M.; Babusiaux, C.; Bailer-Jones, C. A. L.; Barache, C.; Bastian, U.; Beck, M.; Berthier, J.; Bianchi, L.; Biermann, M.; Bombrun, A.; Bossini, D.; Breddels, M.; Brown, A. G. A.; Busonero, D.; Butkevich, A.; Cantat-Gaudin, T.; Carrasco, J. M.; Cheek, N.; Clementini, G.; Creevey, O.; Crowley, C.; David, M.; Davidson, M.; De Angeli, F.; De Ridder, J.; Delbò, M.; Dell'Oro, A.; Diakité, S.; Distefano, E.; Drimmel, R.; Durán, J.; Evans, D. W.; Fabricius, C.; Fabrizio, M.; Fernández-Hernández, J.; Findeisen, K.; Fleitas, J.; Fouesneau, M.; Galluccio, L.; Gracia-Abril, G.; Guerra, R.; Gutiérrez-Sánchez, R.; Helmi, A.; Hernandez, J.; Holl, B.; Hutton, A.; Jean-Antoine-Piccolo, A.; Jevardat de Fombelle, G.; Joliet, E.; Jordi, C.; Juhász, Á.; Klioner, S.; Löffler, W.; Lammers, U.; Lanzafame, A.; Lebzelter, T.; Leclerc, N.; Lecoeur-Taïbi, I.; Lindegren, L.; Marinoni, S.; Marrese, P. M.; Mary, N.; Massari, D.; Messineo, R.; Michalik, D.; Mignard, F.; Molinaro, R.; Molnár, L.; Montegriffo, P.; Mora, A.; Mowlavi, N.; Muinonen, K.; Muraveva, T.; Nienartowicz, K.; Ordenovic, C.; Pancino, E.; Panem, C.; Pauwels, T.; Petit, J.; Plachy, E.; Portell, J.; Racero, E.; Regibo, S.; Reylé, C.; Rimoldini, L.; Ripepi, V.; Riva, A.; Robichon, N.; Robin, A.; Roelens, M.; Romero-Gómez, M.; Sarro, L.; Seabroke, G.; Segovia, J. C.; Siddiqui, H.; Smart, R.; Smith, K.; Sordo, R.; Soria, S.; Spoto, F.; Stephenson, C.; Turon, C.; Vallenari, A.; Veljanoski, J.; Voutsinas, S.

2018-04-01

The second Gaia data release, Gaia DR2, encompasses astrometry, photometry, radial velocities, astrophysical parameters (stellar effective temperature, extinction, reddening, radius, and luminosity), and variability information plus astrometry and photometry for a sample of pre-selected bodies in the solar system. The data collected during the first 22 months of the nominal, five-year mission have been processed by the Gaia Data Processing and Analysis Consortium (DPAC), resulting into this second data release. A summary of the release properties is provided in Gaia Collaboration et al. (2018b). The overall scientific validation of the data is described in Arenou et al. (2018). Background information on the mission and the spacecraft can be found in Gaia Collaboration et al. (2016), with a more detailed presentation of the Radial Velocity Spectrometer (RVS) in Cropper et al. (2018). In addition, Gaia DR2 is accompanied by various, dedicated papers that describe the processing and validation of the various data products. Four more Gaia Collaboration papers present a glimpse of the scientific richness of the data. In addition to this set of refereed publications, this documentation provides a detailed, complete overview of the processing and validation of the Gaia DR2 data. Gaia data, from both Gaia DR1 and Gaia DR2, can be retrieved from the Gaia archive, which is accessible from https://archives.esac.esa.int/gaia. The archive also provides various tutorials on data access and data queries plus an integrated data model (i.e., description of the various fields in the data tables). In addition, Luri et al. (2018) provide concrete advice on how to deal with Gaia astrometry, with recommendations on how best to estimate distances from parallaxes. The Gaia archive features an enhanced visualisation service which can be used for quick initial explorations of the entire Gaia DR2 data set. Pre-computed cross matches between Gaia DR2 and a selected set of large surveys are

Modulation of TRAIL resistance in colon carcinoma cells: Different contributions of DR4 and DR5

International Nuclear Information System (INIS)

Geelen, Caroline MM van; Pennarun, Bodvael; Le, Phuong TK; Vries, Elisabeth GE de; Jong, Steven de

2011-01-01

rhTRAIL is a therapeutic agent, derived from the TRAIL cytokine, which induces apoptosis in cancer cells by activating the membrane death receptors 4 and 5 (DR4 and DR5). Here, we investigated each receptor's contribution to rhTRAIL sensitivity and rhTRAIL resistance. We assessed whether agonistic DR4 or DR5 antibodies could be used to circumvent rhTRAIL resistance, alone or in combination with various chemotherapies. Our study was performed in an isogenic model comprised of the SW948 human colon carcinoma cell line and its rhTRAIL resistant sub-line SW948-TR. Effects of rhTRAIL and agonistic DR4/DR5 antibodies on cell viability were measured using MTT assays and identification of morphological changes characteristic of apoptosis, after acridine orange staining. Sensitivity to the different death receptor ligands was stimulated using pretreatment with the cytokine IFN-gamma and the proteasome inhibitor MG-132. To investigate the mechanisms underlying the changes in rhTRAIL sensitivity, alterations in expression levels of targets of interest were measured by Western blot analysis. Co-immunoprecipitation was used to determine the composition of the death-inducing signalling complex at the cell membrane. SW948 cells were sensitive to all three of the DR-targeting agents tested, although the agonistic DR5 antibody induced only weak caspase 8 cleavage and limited apoptosis. Surprisingly, agonistic DR4 and DR5 antibodies induced equivalent DISC formation and caspase 8 cleavage at the level of their individual receptors, suggesting impairment of further caspase 8 processing upon DR5 stimulation. SW948-TR cells were cross-resistant to all DR-targeting agents as a result of decreased caspase 8 expression levels. Caspase 8 protein expression was restored by MG-132 and IFN-gamma pretreatment, which also re-established sensitivity to rhTRAIL and agonistic DR4 antibody in SW948-TR. Surprisingly, MG-132 but not IFN-gamma could also increase DR5-mediated apoptosis in SW948

Modulation of TRAIL resistance in colon carcinoma cells: Different contributions of DR4 and DR5

Directory of Open Access Journals (Sweden)

de Vries Elisabeth GE

2011-01-01

Full Text Available Abstract Background rhTRAIL is a therapeutic agent, derived from the TRAIL cytokine, which induces apoptosis in cancer cells by activating the membrane death receptors 4 and 5 (DR4 and DR5. Here, we investigated each receptor's contribution to rhTRAIL sensitivity and rhTRAIL resistance. We assessed whether agonistic DR4 or DR5 antibodies could be used to circumvent rhTRAIL resistance, alone or in combination with various chemotherapies. Methods Our study was performed in an isogenic model comprised of the SW948 human colon carcinoma cell line and its rhTRAIL resistant sub-line SW948-TR. Effects of rhTRAIL and agonistic DR4/DR5 antibodies on cell viability were measured using MTT assays and identification of morphological changes characteristic of apoptosis, after acridine orange staining. Sensitivity to the different death receptor ligands was stimulated using pretreatment with the cytokine IFN-gamma and the proteasome inhibitor MG-132. To investigate the mechanisms underlying the changes in rhTRAIL sensitivity, alterations in expression levels of targets of interest were measured by Western blot analysis. Co-immunoprecipitation was used to determine the composition of the death-inducing signalling complex at the cell membrane. Results SW948 cells were sensitive to all three of the DR-targeting agents tested, although the agonistic DR5 antibody induced only weak caspase 8 cleavage and limited apoptosis. Surprisingly, agonistic DR4 and DR5 antibodies induced equivalent DISC formation and caspase 8 cleavage at the level of their individual receptors, suggesting impairment of further caspase 8 processing upon DR5 stimulation. SW948-TR cells were cross-resistant to all DR-targeting agents as a result of decreased caspase 8 expression levels. Caspase 8 protein expression was restored by MG-132 and IFN-gamma pretreatment, which also re-established sensitivity to rhTRAIL and agonistic DR4 antibody in SW948-TR. Surprisingly, MG-132 but not IFN

Dr. Wernher von Braun and Dr. Ernst Stuhlinger Sign Citizenship Certificates

Science.gov (United States)

1955-01-01

The members of the Peenemuende team and their family members were awarded the United States citizenship on April 14, 1955. Pictured here is Dr. Ernst Stuhlinger (middle) and Dr. Wernher von Braun signing U.S. citizenship certificates. Martin Schilling is at left.

Identification of Value Proposition and Development of Innovative Business Models for Demand Response Products and Services Enabled by the DR-BOB Solution

Directory of Open Access Journals (Sweden)

Mario Sisinni

2017-10-01

Full Text Available The work presented is the result of an ongoing European H2020 project entitled DR-BOB Demand Response in Blocks of Buildings (DR-BOB that seeks to integrate existing technologies to create a scalable solution for Demand Response (DR in blocks of buildings. In most EU countries, DR programs are currently limited to the industrial sector and to direct asset control. The DR-BOB solution extends applicability to the building sector, providing predictive building management in blocks of buildings, enabling facilities managers to respond to implicit and explicit DR schemes, and enabling the aggregation of the DR potential of many blocks of buildings for use in demand response markets. The solution consists of three main components: the Local Energy Manager (LEM, which adds intelligence and provides the capacity for predictive building management in blocks of buildings, a Consumer Portal (CP to enable building managers and building occupants to interact with the system and be engaged in demand response operations, and a Decentralized Energy Management System (DEMS®, Siemens plc, Nottingham, England, UK, which enables the aggregation of the DR potential of many blocks of buildings, thus allowing participation in incentive-based demand response with or without an aggregator. The paper reports the key results around Business Modelling development for demand response products and services enabled by the DR-BOB solution. The scope is threefold: (1 illustrate how the functionality of the demand response solution can provide value proposition to underpin its exploitation by four specific customer segments, namely aggregators and three types of Owners of Blocks of Buildings in different market conditions, (2 explore key aspects of the Business Model from the point of view of a demand response solution provider, in particular around most the suitable revenue stream and key partnership, and (3 assess the importance of key variables such as market maturity, user

Construction of new data archive system in RIKEN RI beam factory

International Nuclear Information System (INIS)

Komiyama, M.; Fukunishi, N.; Uchiyama, A.

2012-01-01

RIKEN Radioactive Isotope Beam Factory (RIBF) is a cyclotron-based next-generation radioactive beam facility. RIBF uses two types of control systems; an experimental physics and industrial control system (EPICS)-based system and a group of several non-EPICS-based systems. For each control system there is a corresponding data archiving system in operation, and in order to unify these two data archives, since October 2009 we have been developing a new archiving system. This new data archive system, named RIBF Control Data Archive System (RIBFCAS), is required, at intervals between 1 - 60 s, to collect and store more than 3000 data generated by EPICS controlled devices through EPICS input/output controllers (IOCs). In addition, RIBFCAS must be able to combine the existing non-EPICS-based systems. To fulfill these requirements, a Java-based platform has been created, and client applications are based on Adobe AIR runtime. The RIBFCAS hardware system, therefore, consists of an application server, a database server and client-PCs. Presently, we have succeeded in stably acquiring approximately 3000 data from 22 IOCs every 10 s. Moreover, incorporation of the non-EPICS-based data archive system into RIBFCAS is now in progress. (authors)

Dr Math at your service

CSIR Research Space (South Africa)

Butgereit, L

2012-10-01

Full Text Available In this presentation the author explains how the Dr Math service works; how tutors are recruited to act as Dr Math; and how school pupils can reach Dr Math for help with their mathematics homework....

Perancangan Sistem Informasi Manajemen pada Klinik Skala Kecil (Studi Kasus: Klinik Dr. Jonni

Directory of Open Access Journals (Sweden)

Ayuliana Ayuliana

2014-12-01

Full Text Available The purpose of this research was to develop a database application at dr. Jonni clinic which can be used for processing and recording of operational data with an attractive user interface. Through the integrated database application, data on dr. Jonni clinic would be more structured, therefore data retrieval will go faster and more accurate, data security administration will be increased, data redundancy will be eliminated and service performance clinic dr. Jonni will also be increased. The method of analysis includes the study of literature, examination of documentation, observation, and interviews. While in the design, the method includes application design using the waterfall method models, database design and data modeling application screens using State Transition Diagrams. The results achieved from this research is an application of data base management hospital. With database applications, all data and information can be integrated well, so that it would improve the quality of  services as well as facilitate storing and accessing data. The conclusions obtained from this research is the application of data base management hospital helps in generating quick and accurate information that is used to support operations and decision-making in the clinic dr. Jonni.

Proceedings of RIKEN BNL Research Center workwhop on RHIC spin

Energy Technology Data Exchange (ETDEWEB)

SOFFER,J.

1999-10-06

This RHIC Spin Workshop is the 1999 annual meeting of the RHIC Spin Collaboration, and the second to be hosted at Brookhaven and sponsored by the RIKEN BNL Research Center. The previous meetings were at Brookhaven (1998), Marseille (1996), MIT in 1995, Argonne 1994, Tucson in 1991, and the Polarized Collider Workshop at Penn State in 1990. As noted last year, the Center provides a home for combined work on spin by theorists, experimenters, and accelerator physicists. This proceedings, as last year, is a compilation of 1 page summaries and 5 selected transparencies for each speaker. It is designed to be available soon after the workshop is completed. Speakers are welcome to include web or other references for additional material. The RHIC spin program and RHIC are rapidly becoming reality. RHIC has completed its first commissioning run, as described here by Steve Peggs. The first Siberian Snake for spin has been completed and is being installed in RHIC. A new polarized source from KEK and Triumf with over 1 milliampere of polarized H{sup minus} is being installed, described by Anatoli Zelenski. They have had a successful test of a new polarimeter for RHIC, described by Kazu Kurita and Haixin Huang. Spin commissioning is expected next spring (2000), and the first physics run for spin is anticipated for spring 2001. The purpose of the workshop is to get everyone together about once per year and discuss goals of the spin program, progress, problems, and new ideas. They also have many separate regular forums on spin. There are spin discussion sessions every Tuesday, now organized by Naohito Saito and Werner Vogelsang. The spin discussion schedule and copies of presentations are posted on http://riksg01.rhic.bnl.gov/rsc. Speakers and other spinners are encouraged to come to BNL and to lead a discussion on your favorite idea. They also have regular polarimeter and snake meetings on alternate Thursdays, led by Bill McGahern, the lead engineer for the accelerator spin

Proceedings of RIKEN BNL Research Center workshop on RHIC spin

International Nuclear Information System (INIS)

Soffer, J.

1999-01-01

This RHIC Spin Workshop is the 1999 annual meeting of the RHIC Spin Collaboration, and the second to be hosted at Brookhaven and sponsored by the RIKEN BNL Research Center. The previous meetings were at Brookhaven (1998), Marseille (1996), MIT in 1995, Argonne 1994, Tucson in 1991, and the Polarized Collider Workshop at Penn State in 1990. As noted last year, the Center provides a home for combined work on spin by theorists, experimenters, and accelerator physicists. This proceedings, as last year, is a compilation of 1 page summaries and 5 selected transparencies for each speaker. It is designed to be available soon after the workshop is completed. Speakers are welcome to include web or other references for additional material. The RHIC spin program and RHIC are rapidly becoming reality. RHIC has completed its first commissioning run, as described here by Steve Peggs. The first Siberian Snake for spin has been completed and is being installed in RHIC. A new polarized source from KEK and Triumf with over 1 milliampere of polarized H minus is being installed, described by Anatoli Zelenski. They have had a successful test of a new polarimeter for RHIC, described by Kazu Kurita and Haixin Huang. Spin commissioning is expected next spring (2000), and the first physics run for spin is anticipated for spring 2001. The purpose of the workshop is to get everyone together about once per year and discuss goals of the spin program, progress, problems, and new ideas. They also have many separate regular forums on spin. There are spin discussion sessions every Tuesday, now organized by Naohito Saito and Werner Vogelsang. The spin discussion schedule and copies of presentations are posted on http://riksg01.rhic.bnl.gov/rsc. Speakers and other spinners are encouraged to come to BNL and to lead a discussion on your favorite idea. They also have regular polarimeter and snake meetings on alternate Thursdays, led by Bill McGahern, the lead engineer for the accelerator spin effort

Large Customers (DR Sellers)

Energy Technology Data Exchange (ETDEWEB)

Kiliccot, Sila [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

2011-10-25

State of the large customers for demand response integration of solar and wind into electric grid; openADR; CAISO; DR as a pseudo generation; commercial and industrial DR strategies; California regulations

Value of HLA-DR genotype in systemic lupus erythematosus and lupus nephritis: a meta-analysis.

Science.gov (United States)

Niu, Zhili; Zhang, Pingan; Tong, Yongqing

2015-01-01

Human leukocyte antigen (HLA)-DRB1 allele polymorphisms have been reported to be associated with systemic lupus erythematosus (SLE) susceptibility, but the results of these previous studies have been inconsistent. The purpose of the present study was to systematically summarize and explore whether specific HLA-DRB1 alleles confer susceptibility or resistance to SLE and lupus nephritis. This review was guided by the preferred reporting items for systematic reviews and meta-analyses (PRISMA) approach. A comprehensive search was made for articles from PubMed, Medline, Elsevier Science, Springer Link and Cochrane Library database. A total of 25 case-control studies on the relationship between gene polymorphism of HLA-DRB l and SLE were performed and data were analyzed and processed using Review Manager 5.2 and Stata 11.0. At the allelic level, HLA-DR4, DR11 and DR14 were identified as protective factors for SLE (0.79 [0.69,0.91], P  0.05). DR4 and 11 (OR, 0.55 [0.39, 0.79], P  0.05; 0.90 [0.64, 1.27], P > 0.05; 0.61 [0.36, 1.03], P > 0.05, respectively) were not statistically significant between the lupus nephritis and control groups. The HLA-DR4, DR11, DR14 alleles might be protective factors for SLE and HLA-DR3, DR9, DR15 were potent risk factors. In addition, HLA-DR4 and DR11 alleles might be protective factors for lupus nephritis and DR3 and DR15 suggest a risk role. These results proved that HLA-DR3, DR15, DR4 and DR11 might be identified as predictors for lupus nephritis and SLE. © 2014 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd.

Prava trećih država u gospodarskom pojasu obalne države

Directory of Open Access Journals (Sweden)

Marina Vokić Žužul

2003-12-01

Full Text Available Predmet ovoga rada je analiza prava koja u gospodarskom pojasu obalne države mogu ostvarivati sve obalne i neobalne države. uz detaljan prikaz pravnog uređenja materije u odredbama Konvencije o pravu mora iz 1982., razmatraju se i vladajuća gledišta međunarodnopravne doktrine te rješenja u zakonodavstvima pojedinih zemalja. Posebna pozornost je posvećena ostvarivanju tuh prava u potencijalnom hrvatskom gospodarskom pojasu, prvenstveno mogućim zahtjevima od strane susjednih neobalnih država i država u nepovoljnom geografskom položaju. Sva pitanja razmatrana u ovom radu upućuju na zaključak da ispunjavanje dužnosti prema drugim državama u budućem gospodarskom pojasu RH ne bi trebalo imati utjecaja na donošenje odluke o njegovom proglašenju.

BEopt-CA (Ex): A Tool for Optimal Integration of EE, DR and PV in Existing California Homes

Energy Technology Data Exchange (ETDEWEB)

Christensen, Craig [National Renewable Energy Lab. (NREL), Golden, CO (United States); Horowitz, Scott [National Renewable Energy Lab. (NREL), Golden, CO (United States); Maguire, Jeff [National Renewable Energy Lab. (NREL), Golden, CO (United States); Velasco, Paulo Tabrares [National Renewable Energy Lab. (NREL), Golden, CO (United States); Springer, David [Davis Energy Group, Davis, CA (United States); Coates, Peter [Davis Energy Group, Davis, CA (United States); Bell, Christy [Davis Energy Group, Davis, CA (United States); Price, Snuller [Energy & Environmental Economics, San Francisco, CA (United States); Sreedharan, Priya [Energy & Environmental Economics, San Francisco, CA (United States); Pickrell, Katie [Energy & Environmental Economics, San Francisco, CA (United States)

2014-04-01

This project targeted the development of a software tool, BEopt-CA (Ex) (Building Energy Optimization Tool for California Existing Homes), that aims to facilitate balanced integration of energy efficiency (EE), demand response (DR), and photovoltaics (PV) in the residential retrofit1 market. The intent is to provide utility program managers and contractors in the EE/DR/PV marketplace with a means of balancing the integration of EE, DR, and PV

First results from the new RIKEN superconducting electron cyclotron resonance ion source (invited).

Science.gov (United States)

Nakagawa, T; Higurashi, Y; Ohnishi, J; Aihara, T; Tamura, M; Uchiyama, A; Okuno, H; Kusaka, K; Kidera, M; Ikezawa, E; Fujimaki, M; Sato, Y; Watanabe, Y; Komiyama, M; Kase, M; Goto, A; Kamigaito, O; Yano, Y

2010-02-01

The next generation heavy ion accelerator facility, such as the RIKEN radio isotope (RI) beam factory, requires an intense beam of high charged heavy ions. In the past decade, performance of the electron cyclotron resonance (ECR) ion sources has been dramatically improved with increasing the magnetic field and rf frequency to enhance the density and confinement time of plasma. Furthermore, the effects of the key parameters (magnetic field configuration, gas pressure, etc.) on the ECR plasma have been revealed. Such basic studies give us how to optimize the ion source structure. Based on these studies and modern superconducting (SC) technology, we successfully constructed the new 28 GHz SC-ECRIS, which has a flexible magnetic field configuration to enlarge the ECR zone and to optimize the field gradient at ECR point. Using it, we investigated the effect of ECR zone size, magnetic field configuration, and biased disk on the beam intensity of the highly charged heavy ions with 18 GHz microwaves. In this article, we present the structure of the ion source and first experimental results with 18 GHz microwave in detail.

Enrico Fermi Awards Ceremony for Dr. Mildred S. Dresselhaus and Dr. Burton Richter, May 2012 (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

International Nuclear Information System (INIS)

Chu, Steven

2012-01-01

The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On May 7, 2012 it was conferred upon two exceptional scientists: Dr. Mildred Dresselhaus, 'for her scientific leadership, her major contributions to science and energy policy, her selfless work in science education and the advancement of diversity in the scientific workplace, and her highly original and impactful research,' and Dr. Burton Richter, 'for the breadth of his influence in the multiple disciplines of accelerator physics and particle physics, his profound scientific discoveries, his visionary leadership as SLAC Director, his leadership of science, and his notable contributions in energy and public policy.' Dr. John Holder, Director of the White House Office of Science and Technology Policy, opened the ceremony, and Dr. Bill Brinkman, Director of DOE's Office of Science introduced the main speaker, Dr. Steven Chu, U.S. Energy Secretary.

In Memoriam: Dr. Frank John Fenner

Centers for Disease Control (CDC) Podcasts

This podcast reflects on one of the greatest pioneers in virology, Dr. Frank John Fenner. Dr. Frederick Murphy, a member of EID's editorial board and the Institute of Medicine, and professor of Pathology at the University of Texas Medical Branch in Galveston, shares professional and personal stories of Dr. Frank Fenner.

95 GHz methanol masers near DR 21 and DR 21(OH)

International Nuclear Information System (INIS)

Plambeck, R.L.; Menten, K.M.

1990-01-01

The BIMA array is used to map the 95-GHz 8(0) to 7 1A(+) transition of methanol and the 98-GHz J = 2-1 transition of CS toward the DR 21(OH) and DR 21 star-forming regions. Several strong methanol masers were found. The positions of the two brightest masers were measured with an accuracy of about + or - 0.3 arcsec. Toward DR 21(OH), the positions, velocities, and line shapes of the 95 GHz masers are in excellent agreement with those of the 84-GHz 5(-1) to 4 () methanol masers previously mapped by Batrla and Menten (1988), demonstrating that maser emission in both transitions originates from the same clumps of gas. The methanol masers are offset from CS emission peaks and from other known infrared and maser sources; they may possibly be clustered along the interface between outflows, traced by shock-excited H2 emission, and dense ambient gas, traced by CS emission. 25 refs

The RIKEN gas-filled recoil separator and a possible new approach to superheavy elements by the (HI, αxn) reaction

International Nuclear Information System (INIS)

Nomura, T.

1990-10-01

The (HI, αxn) reaction, in which precompound α particle emission takes place, is shown to occur significantly even near the Coulomb barrier. Because the α emission can efficiently cool down a highly excited nucleus both in energy and angular momentum, it is considered to be very effective for production of heavy elements like SHE. However, the angular distributions of residual nuclei produced in this reaction are side-peaked, requiring a recoil-type separator with large angular acceptance when it is applied for collection of the relevant nuclei. A brief description is given about a gas-filled separator recently constructed at RIKEN, which meets the above requirement. (author)

Dr Stanislaw Huskowski, Mayor of Wroclaw, Poland

CERN Multimedia

Patrice Loïez

2002-01-01

Dr Stanislaw Huskowski, Mayor of Wroclaw, Poland visiting the ATLAS magnet assembly hall, building 180 with Mr Carlo Lamprecht, State Councillor, Dr Stanislaw Huskowski and Dr Peter Jenni, ATLAS Spokesperson

PROCEEDINGS OF RIKEN/BNL RESEARCH CENTER WORKSHOP FUTURE TRANSVERSITY MEASUREMENTS (VOLUME 29)

International Nuclear Information System (INIS)

Boer, D.; Grosse Perdekamp, M.

2001-01-01

The RIKEN-BNL Research Center workshop on ''Future Transversity Measurements'' was held at BNL from September 18-20, 2000. The main goal of the workshop was to explore future measurements of transversity distributions. This issue is of importance to the RHIC experiments, which will study polarized proton-proton collisions with great precision. One of the workshop's goals was to enhance interactions between the DIS community at HERA and the spin community at RHIC in this field. The workshop has been well received by the participants; the number of 69 registered participants demonstrates broad interest in the workshop's topics. The program contained 35 talks and there was ample time for lively discussions. The program covered all recent work in the field and in addition some very elucidating educational talks were given. At the workshop the present status of the field was discussed and it has succeeded in stimulating new experimental and theoretical studies (e.g. model calculations for interference fragmentation functions (IFF), IFF analysis at DELPHI). It also functioned to focus attention on the open questions that need to be resolved for near future experiments. In general, the conclusions were optimistic, i.e. measuring the transversity functions seems to be possible, although some new experimental hurdles will have to be taken

Evolution and current status of demand response (DR) in electricity markets: Insights from PJM and NYISO

International Nuclear Information System (INIS)

Walawalkar, Rahul; Fernands, Stephen; Thakur, Netra; Chevva, Konda Reddy

2010-01-01

In electricity markets, traditional demand side management programs are slowly getting replaced with demand response (DR) programs. These programs have evolved since the early pilot programs launched in late 1990s. With the changes in market rules the opportunities have generally increased for DR for participating in emergency, economic and ancillary service programs. In recent times, various regulators have suggested that DR can also be used as a solution to meet supply - demand fluctuations in scenarios with significant penetration of variable renewable sources in grid. This paper provides an overview of the evolution of the DR programs in PJM and NYISO markets as well as analyzes current opportunities. Although DR participation has grown, most of the current participation is in the reliability programs, which are designed to provide load curtailment during peak days. This suggests that there is a significant gap between perception of ability of DR to mitigate variability of renewables and reality of current participation. DR in future can be scaled to play a more dynamic role in electricity markets, but that would require changes both on technology as well as policy front. Advances in building technologies and energy storage combined with appropriate price signals can lead to enhanced DR participation. (author)

Proceedings of RIKEN BNL Research Center Workshop: The Physics of W and Z Bosons

Energy Technology Data Exchange (ETDEWEB)

Dawson, S.; Okada, K.; Patwa, A.; Qiu, J.; Surrow, B.

2010-06-24

A two-day workshop on 'The Physics of Wand Z Bosons' Was held at the RIKEN BNL Research Center at Brookhaven National Laboratory on June 24-25, 2010. With the recent release of the first measurement of W bosons in proton-proton collisions at RHIC and the first observation of W events at the LHC, the workshop was a timely opportunity to bring together experts from both the high energy particle and nuclear physics communities to share their ideas and expertise on the physics of Wand Z bosons, with the aim of fully exploring the potential of the W/Z physics programs at RHIC and the LHC. The focus was on the production and measurement of W/Z bosons in both polarized and unpolarized proton-proton collisions, and the role of W/Z production in probing the parton flavor and helicity structure of the colliding proton and in the search for new physics. There were lively discussions about the potential and future prospects of W/Z programs at RHIC, Tevatron, and the LHC.

Dr Stanislaw Huskowski, Mayor of Wroclaw, Poland

CERN Multimedia

Patrice Loïez

2002-01-01

Dr Stanislaw Huskowski, Mayor of Wroclaw, Poland visiting the ATLAS magnet assembly hall, building 180. From l to r: Mr Carlo Lamprecht, State Councillor, Dr Stanislaw Huskowski and Dr Peter Jenni, ATLAS Spokesperson

105-DR Large Sodium Fire Facility closure plan

International Nuclear Information System (INIS)

1993-05-01

The Hanford Site, located northwest of the city of Richland, Washington, houses reactors, chemical-separation systems, and related facilities used for the production of special nuclear materials, and activities associated with nuclear energy development. The 105-DR Large Sodium Fire Facility (LSFF), which was in operation from about 1972 to 1986, was a research laboratory that occupied the former ventilation supply room on the southwest side of the 105-DR Reactor facility. The LSFF was established to provide a means of investigating fire and safety aspects associated with large sodium or other metal alkali fires in the liquid metal fast breeder reactor (LMFBR) facilities. The 105-DR Reactor facility was designed and built in the 1950's and is located in the 100-D Area of the Hanford Site. The building housed the 105-DR defense reactor, which was shut down in 1964. The LSFF was initially used only for engineering-scale alkali metal reaction studies. In addition, the Fusion Safety Support Studies program sponsored intermediate-size safety reaction tests in the LSFF with lithium and lithium lead compounds. The facility has also been used to store and treat alkali metal waste, therefore the LSFF is subject to the regulatory requirements for the storage and treatment of dangerous waste. Closure will be conducted pursuant to the requirements of the Washington Administrative Code (WAC) 173-303-610. This closure plan presents a description of the facility, the history of waste managed, and the procedures that will be followed to close the LSFF as an Alkali Metal Treatment Facility. No future use of the LSFF is expected

Strategies for dose reduction in ordinary radiographic examinations using CR and DR

International Nuclear Information System (INIS)

Willis, C.E.

2004-01-01

Uncoupling of display from acquisition in computed radiography (CR) and digital radiography (DR) introduces the potential for systematic overexposure without necessarily compromising image quality. Although the magnitude of radiation doses in general radiography is low compared to computed tomography and fluoroscopy, the dose to the patient is more critical in pediatric examinations than in adults, because of the greater radiosensitivity of children. This manuscript examines a variety of countermeasures for managing radiation doses in pediatric CR and DR examinations, including use of derived exposure indicators, modifications of imaging practice, and development of more efficient radiographic detectors. (orig.)

Dr Pugh: a poisoner?

Science.gov (United States)

Paull, J D; Morris, G M

2012-07-01

On 16 February 1845 the Reverend W. H. Browne, rector of St John's Church in Launceston, Van Diemen's Land, wrote in his journal, "My dear Wife died very suddenly almost immediately after and in consequence of taking a preparation of Hyd. Cyan. Acid prepared & supplied by Dr Pugh". This journal entry raises a number of questions. Was Dr Pugh treating a condition which he thought merited that treatment or was it a ghastly mistake? Was Caroline Browne suffering from pulmonary tuberculosis? Was hydrocyanic acid an accepted treatment at that time? Did Mrs Browne take the wrong dose? Was an incorrect concentration of the drug prepared by Dr Pugh? Did he use the wrong pharmacopoeia in preparing the hydrocyanic acid? Why was there no inquest? Only some of these questions can be answered.

PERAN PUBLIC RELATIONS SEBAGAI PENDUKUNG MANAJEMEN DI RUMAH SAKIT UMUM DR. PIRNGADI KOTA MEDAN

Directory of Open Access Journals (Sweden)

Indah Kemala Hasibuan

2017-08-01

Full Text Available The research is titled "The Role of Public Relations as a Management Support Hospital General Dr. Pirngadi Medan City "and discusses the role of public relations in order to improve the image of the hospital which describes the public relations image of the hospital to maintain (maintenance of image and restore the image of the hospital (recovery of image when carrying out its role as a supporter of management. This study aims to answer the problems that have been formulated. The detailed objectives of this study was to determine achievable extent of successful public relations duties to support the management to minimize patient complaints about inpatient services Jamkesmas participants in improving the image of the hospital in General Hospital Dr. Pirngadi Medan. The study population was inpatients General Hospital Dr. Pirngadi Jamkesmas Medan which is a participant during the month of January 2009 and aged 17 to 50 years. While the number of samples used to determine the Taro Yamane and using proportional random sampling technique. To answer the problems that have been formulated, used descriptive method with quantitative approach. From the analysis found the success rate of maintaining public relations image of the hospital by providing the best services at 65.12%, and restore the image of the hospital by providing the right solution for 62.79% proving that the role of public relations as a management support works.

Pathogenesis of Human Diffusely Adhering Escherichia coli Expressing Afa/Dr Adhesins (Afa/Dr DAEC): Current Insights and Future Challenges

Science.gov (United States)

2014-01-01

SUMMARY The pathogenicity and clinical pertinence of diffusely adhering Escherichia coli expressing the Afa/Dr adhesins (Afa/Dr DAEC) in urinary tract infections (UTIs) and pregnancy complications are well established. In contrast, the implication of intestinal Afa/Dr DAEC in diarrhea is still under debate. These strains are age dependently involved in diarrhea in children, are apparently not involved in diarrhea in adults, and can also be asymptomatic intestinal microbiota strains in children and adult. This comprehensive review analyzes the epidemiology and diagnosis and highlights recent progress which has improved the understanding of Afa/Dr DAEC pathogenesis. Here, I summarize the roles of Afa/Dr DAEC virulence factors, including Afa/Dr adhesins, flagella, Sat toxin, and pks island products, in the development of specific mechanisms of pathogenicity. In intestinal epithelial polarized cells, the Afa/Dr adhesins trigger cell membrane receptor clustering and activation of the linked cell signaling pathways, promote structural and functional cell lesions and injuries in intestinal barrier, induce proinflammatory responses, create angiogenesis, instigate epithelial-mesenchymal transition-like events, and lead to pks-dependent DNA damage. UTI-associated Afa/Dr DAEC strains, following adhesin-membrane receptor cell interactions and activation of associated lipid raft-dependent cell signaling pathways, internalize in a microtubule-dependent manner within urinary tract epithelial cells, develop a particular intracellular lifestyle, and trigger a toxin-dependent cell detachment. In response to Afa/Dr DAEC infection, the host epithelial cells generate antibacterial defense responses. Finally, I discuss a hypothetical role of intestinal Afa/Dr DAEC strains that can act as “silent pathogens” with the capacity to emerge as “pathobionts” for the development of inflammatory bowel disease and intestinal carcinogenesis. PMID:25278576

From Mxit to Dr Math

CSIR Research Space (South Africa)

Botha, Adèle

2013-02-01

Full Text Available In 2007, Laurie Butgereit, a researcher at the CSIR Meraka Institute, started to use Mxit as a communication channel to tutor her son in mathematics. Her son and a number of his friends logged in, and Dr Math was born. At the inception of Dr Math...

Pathogenesis of human diffusely adhering Escherichia coli expressing Afa/Dr adhesins (Afa/Dr DAEC): current insights and future challenges.

Science.gov (United States)

Servin, Alain L

2014-10-01

The pathogenicity and clinical pertinence of diffusely adhering Escherichia coli expressing the Afa/Dr adhesins (Afa/Dr DAEC) in urinary tract infections (UTIs) and pregnancy complications are well established. In contrast, the implication of intestinal Afa/Dr DAEC in diarrhea is still under debate. These strains are age dependently involved in diarrhea in children, are apparently not involved in diarrhea in adults, and can also be asymptomatic intestinal microbiota strains in children and adult. This comprehensive review analyzes the epidemiology and diagnosis and highlights recent progress which has improved the understanding of Afa/Dr DAEC pathogenesis. Here, I summarize the roles of Afa/Dr DAEC virulence factors, including Afa/Dr adhesins, flagella, Sat toxin, and pks island products, in the development of specific mechanisms of pathogenicity. In intestinal epithelial polarized cells, the Afa/Dr adhesins trigger cell membrane receptor clustering and activation of the linked cell signaling pathways, promote structural and functional cell lesions and injuries in intestinal barrier, induce proinflammatory responses, create angiogenesis, instigate epithelial-mesenchymal transition-like events, and lead to pks-dependent DNA damage. UTI-associated Afa/Dr DAEC strains, following adhesin-membrane receptor cell interactions and activation of associated lipid raft-dependent cell signaling pathways, internalize in a microtubule-dependent manner within urinary tract epithelial cells, develop a particular intracellular lifestyle, and trigger a toxin-dependent cell detachment. In response to Afa/Dr DAEC infection, the host epithelial cells generate antibacterial defense responses. Finally, I discuss a hypothetical role of intestinal Afa/Dr DAEC strains that can act as "silent pathogens" with the capacity to emerge as "pathobionts" for the development of inflammatory bowel disease and intestinal carcinogenesis. Copyright © 2014, American Society for Microbiology. All Rights

In Memoriam: Dr. Frank John Fenner

Centers for Disease Control (CDC) Podcasts

2011-04-22

This podcast reflects on one of the greatest pioneers in virology, Dr. Frank John Fenner. Dr. Frederick Murphy, a member of EID's editorial board and the Institute of Medicine, and professor of Pathology at the University of Texas Medical Branch in Galveston, shares professional and personal stories of Dr. Frank Fenner.  Created: 4/22/2011 by National Center for Emerging Zoonotic and Infectious Diseases (NCEZID).   Date Released: 4/26/2011.

Dr. von Braun Briefing Walt Disney

Science.gov (United States)

1965-01-01

Dr. von Braun began his association with Walt Disney in the 1950s when the rocket scientist appeared in three Disney television productions related to the exploration of space. Years later, Dr. von Braun invited Disney and his associates to tour the Marshall Space Flight Center (MSFC) in Huntsville, Alabama. This photograph is dated April 13, 1965. From left are R.J. Schwinghamer from the MSFC, Disney, B.J. Bernight, and Dr. von Braun.

Dr. Biswell's influence on the development of prescribed burning in California

Science.gov (United States)

Jan W.\\t van Wagtendonk

1995-01-01

Prescribed burning in California has evolved from the original practices of the Native Americans, through years of experimentation and controversy, to finally become an accepted ecosystem management activity. When Dr. Harold Biswell arrived in California, he began research on improving game range by using prescribed fires and on understory burning in ponderosa pine (...

PROCEEDINGS OF RIKEN/BNL RESEARCH CENTER WORKSHOP FUTURE TRANSVERSITY MEASUREMENTS (VOLUME 29).

Energy Technology Data Exchange (ETDEWEB)

Boer, D.; Grosse Perdekamp, M.

2001-01-02

The RIKEN-BNL Research Center workshop on ''Future Transversity Measurements'' was held at BNL from September 18-20, 2000. The main goal of the workshop was to explore future measurements of transversity distributions. This issue is of importance to the RHIC experiments, which will study polarized proton-proton collisions with great precision. One of the workshop's goals was to enhance interactions between the DIS community at HERA and the spin community at RHIC in this field. The workshop has been well received by the participants; the number of 69 registered participants demonstrates broad interest in the workshop's topics. The program contained 35 talks and there was ample time for lively discussions. The program covered all recent work in the field and in addition some very elucidating educational talks were given. At the workshop the present status of the field was discussed and it has succeeded in stimulating new experimental and theoretical studies (e.g. model calculations for interference fragmentation functions (IFF), IFF analysis at DELPHI). It also functioned to focus attention on the open questions that need to be resolved for near future experiments. In general, the conclusions were optimistic, i.e. measuring the transversity functions seems to be possible, although some new experimental hurdles will have to be taken.

World Class Facilities Management

DEFF Research Database (Denmark)

Malmstrøm, Ole Emil; Jensen, Per Anker

2013-01-01

Alle der med entusiasme arbejder med Facilities Management drømmer om at levere World Class. DFM drømmer om at skabe rammer og baggrund for, at vi i Danmark kan bryste os at være blandt de førende på verdensplan. Her samles op på, hvor tæt vi er på at nå drømmemålet.......Alle der med entusiasme arbejder med Facilities Management drømmer om at levere World Class. DFM drømmer om at skabe rammer og baggrund for, at vi i Danmark kan bryste os at være blandt de førende på verdensplan. Her samles op på, hvor tæt vi er på at nå drømmemålet....

Status of beam line detectors for the BigRIPS fragment separator at RIKEN RI Beam Factory. Issues on high rates and resolution

International Nuclear Information System (INIS)

Sato, Yuki; Fukuda, Naoki; Takeda, Hiroyuki

2015-01-01

A multiple sampling ionization chamber (MUSIC) and parallel-plate avalanche counters (PPACs) were installed within the superconducting in-flight separator, named BigRIPS, at the RIKEN Nishina Center for particle identification of RI beams. The MUSIC detector showed negligible charge collection inefficiency from recombination of electrons and ions, up to a 99-kcps incidence rate for high-energy heavy ions. For the PPAC detectors, the electrical discharge durability for incident heavy ions was improved by changing the electrode material. Finally, we designed a single crystal diamond detector, which is under development for TOF measurements of high-energy heavy ions, that has a very fast response time (pulse width <1 ns). (author)

Status of Beam Line Detectors for the BigRIPS Fragment Separator at RIKEN RI Beam Factory: Issues on High Rates and Resolution

Science.gov (United States)

Sato, Yuki; Fukuda, Naoki; Takeda, Hiroyuki; Kameda, Daisuke; Suzuki, Hiroshi; Shimizu, Yohei; Ahn, DeukSoon; Murai, Daichi; Inabe, Naohito; Shimaoka, Takehiro; Tsubota, Masakatsu; Kaneko, Junichi H.; Chayahara, Akiyoshi; Umezawa, Hitoshi; Shikata, Shinichi; Kumagai, Hidekazu; Murakami, Hiroyuki; Sato, Hiromi; Yoshida, Koichi; Kubo, Toshiyuki

A multiple sampling ionization chamber (MUSIC) and parallel-plate avalanche counters (PPACs) were installed within the superconducting in-flight separator, named BigRIPS, at the RIKEN Nishina Center for particle identification of RI beams. The MUSIC detector showed negligible charge collection inefficiency from recombination of electrons and ions, up to a 99-kcps incidence rate for high-energy heavy ions. For the PPAC detectors, the electrical discharge durability for incident heavy ions was improved by changing the electrode material. Finally, we designed a single crystal diamond detector, which is under development for TOF measurements of high-energy heavy ions, that has a very fast response time (pulse width <1 ns).

Focal plane detector for QDD spectrography in Institute of Nuclear Study and detector for SMART 2nd focal plane in RIKEN

Energy Technology Data Exchange (ETDEWEB)

Fuchi, Yoshihide [Tokyo Univ., Tanashi (Japan). Inst. for Nuclear Study

1996-09-01

The focal plane detector for QDD spectrography in Institute of Nuclear Study was composed of drift space and a proportional counter tube, and the latter is composed of position detector and two delta E detector for recognizing the particles. In this detector, a uniform parallel electric field can be obtained by placing a guard plate at the same height as that of a drift plate outer place of the detector. On the other hand, the detector for SMART 2nd focal plate in RIKEN is composed of drift space and a single wire proportional counter, and has two cathode read out single wire drift counters set so as to hold the focal plane. (G.K.)

Proceedings of RIKEN BNL Research Center Workshop: Progress in High-pT Physics at RHIC

Energy Technology Data Exchange (ETDEWEB)

Bazilevsky, A.; Bland, L.; Vogelsang, W.

2010-03-17

This volume archives the presentations at the RIKEN BNL Research Center workshop 'Progress in High-PT Physics at RHIC', held at BNL in March 2010. Much has been learned from high-p{sub T} physics after 10 years of RHIC operations for heavy-ion collisions, polarized proton collisions and d+Au collisions. The workshop focused on recent progress in these areas by both theory and experiment. The first morning saw review talks on the theory of RHIC high-p{sub T} physics by G. Sterman and J. Soffer, and on the experimental results by M. Tannenbaum. One of the most exciting recent results from the RHIC spin program is the first observation of W bosons and their associated single-spin asymmetry. The new preliminary data were reported on the first day of our workshop, along with a theoretical perspective. There also were detailed discussions on the global analysis of polarized parton distributions, including the knowledge on gluon polarization and the impact of the W-data. The main topic of the second workshop day were single-transverse spin asymmetries and their analysis in terms of transverse-momentum dependent parton distributions. There is currently much interest in a future Drell-Yan program at RHIC, thanks to the exciting physics opportunities this would offer. This was addressed in some of the talks. There also were presentations on the latest results on transverse-spin physics from HERMES and BELLE. On the final day of the workshop, the focus shifted toward forward and small-x physics at RHIC, which has become a cornerstone of the whole RHIC program. Exciting new data were presented and discussed in terms of their possible implications for our understanding of strong color-field phenomena in QCD. In the afternoon, there were discussions of nuclear parton distributions and jet observables, among them fragmentation. The workshop was concluded with outlooks toward the near-term (LHC, JLab) and longer-term (EIC) future. The workshop has been a great success

Modulation of TRAIL resistance in colon carcinoma cells : Different contributions of DR4 and DR5

NARCIS (Netherlands)

van Geelen, Caroline M. M.; Pennarun, Bodvael; Le, Phuong T. K.; de Vries, Elisabeth G. E.; de Jong, Steven

2011-01-01

Background: rhTRAIL is a therapeutic agent, derived from the TRAIL cytokine, which induces apoptosis in cancer cells by activating the membrane death receptors 4 and 5 (DR4 and DR5). Here, we investigated each receptor's contribution to rhTRAIL sensitivity and rhTRAIL resistance. We assessed whether

Analysis of DR4 haplotypes in insulin dependent diabetes (IDD)

International Nuclear Information System (INIS)

Monos, D.S.; Radka, S.F.; Zmijewski, C.M.; Kamoun, M.

1986-01-01

Population studies indicate that HLA-DR4 is implicated in the susceptibility of IDD. However, biochemical characterization of the serologically defined DR4 haplotype from normal individuals revealed five DR4 and three DQW3 molecular forms. Hence, in this study, they investigated the heterogeneity of the DR4 haplotype, using B-lymphoblastoid cell lines (B-LCL) generated from patients with IDD and seropositive for DR4. Class II molecules, metabolically labeled with 35 S-methionine, were immunoprecipitated with monoclonal antibodies specific for DR(L243), DQ(N297), DQW3(IVD12) or DR and DQ(SG465) and analyzed by two-dimensional polyacrylamide gel electrophoresis (2D-PAGE). The isoelectrofocusing (IEF) conditions employed in this study allow representation only of the DR4 haplotype from either DR3/4 or DR4/4 cell lines. The analysis of six different DR4 haplotypes from seven IDD patients, revealed the presence of two DR4 β and two DQW3 β chains. Three of the six DR4 β haplotypes analyzed shared the same DR4 β chain and three others shared a different one. Additionally five of the six haplotypes shared a different one. Additionally five of the six haplotypes shared the same DQW3 β chain and only one was carrying a different one. Different combinations of the two DR4 and two DQW3 β chains constitute three distinct patterns of DR4 haplotypes. These results suggest the prevalence of a DQW3 β chain in the small sample of IDD patients studied. Studies of a large number of patients should clarify whether IDD is associated with unique variants of DR4 or DQW3 β chains

Dr. von Braun and Dr. Stuhlinger With a Model of the Nuclear-Electric Vehicles

Science.gov (United States)

2004-01-01

In this photo, taken at the Walt Disney Studios in California, Dr. Wernher von Braun and Dr. Ernst Stuhlinger are shown discussing the concepts of nuclear-electric spaceships designed to undertake the mission to the planet Mars. As a part of the Disney 'Tomorrowland' series on the exploration of space, the nuclear-electric vehicles were shown in the last three television films, entitled 'Mars and Beyond,' which first aired in December 1957.

Dr. David Syz, State Secretary for Economic Affairs, Switzerland

CERN Multimedia

Patrice Loïez

2003-01-01

Photo 01: Dr. David Syz (left) with Professor Roger Cashmore, Research Director for Collider Programmes.Photo 02: Dr. David Syz signing the VIP visitors' book, with Prof. Roger Cashmore.Photo 03: Dr. David Syz signing the VIP visitors' book.Photo 04: Handshake between Dr. David Syz (left) and Prof. Roger Cashmore.

An Interview with Dr. Walter Lear

Directory of Open Access Journals (Sweden)

The Editors

2009-03-01

Full Text Available In this issue of the English version of Social Medicine we are publishing the first of several pamphlets loaned to us by the US Health Activism History Collection. To introduce this collection we travelled to Philadelphia on June 18, 2008 to interview Dr. Walter J. Lear. Dr Lear, born in 1923, is the person responsible for the collection. In a wide-ranging interview in his home Dr. Lear discussed his personal background, the origins and purpose of the collection, the impact of the McCarthy period on the US health left, as well as his vision for the future.

105-DR Large Sodium Fire Facility closure activities evaluation report

International Nuclear Information System (INIS)

Adler, J.G.

1996-01-01

This report evaluates the closure activities at the 105-DR Large Sodium Fire Facility. The closure activities discussed include: the closure activities for the structures, equipment, soil, and gravel scrubber; decontamination methods; materials made available for recycling or reuse; and waste management. The evaluation compares these activities to the regulatory requirements and closure plan requirements. The report concludes that the areas identified in the closure plan can be clean closed

HLA-DR expression and disease activity in ulcerative colitis

DEFF Research Database (Denmark)

Poulsen, L O; Elling, P; Sørensen, Flemming Brandt

1986-01-01

In 12 patients with active ulcerative colitis (UC) the rectal epithelial cells were analyzed for HLA-DR antigens by an immunohistochemical technique. The clinical, rectoscopic, and histologic stages were also determined. The investigations were carried out at the beginning of the study and 2 weeks...... and 3 months later. The rectal epithelial cells were HLA-DR-positive in all patients at the first two examinations. After 3 months five patients had changed to an HLA-DR-negative stage, whereas the other seven patients remained HLA-DR-positive. Closer analyses showed that expression/nonexpression of HLA-DR...... antigens on rectal epithelial cells of patients with UC could not be predicted from the clinical, rectoscopic, or histologic findings. HLA-DR expression is normally restricted to immunocompetent cells. The presence of HLA-DR antigens on epithelial cells may be a consequence of immunological reactions...

HLA Dr beta 1 alleles in Pakistani patients with rheumatoid arthritis

International Nuclear Information System (INIS)

Naqi, N.; Ahmed, T.A.; Bashir, M.M.

2011-01-01

Objective: To determine frequencies of HLA DR beta 1 alleles in rheumatoid arthritis in Pakistani patients. Study Design: Cross sectional / analytical study. Place and Duration of Study: Department of Immunology, Armed Forces Institute of Pathology, Rawalpindi in collaboration with Rheumatology departments of Military Hospital, Rawalpindi and Fauji Foundation Hospital, Rawalpindi, from January 2009 to January 2010. Methodology: HLA DR beta 1 genotyping of one hundred Pakistani patients, diagnosed as having RA as per American College of Rheumatology revised criteria 1987, was done. HLA DR beta 1 genotyping was carried out at allele group level (DR beta 1*01-DR beta 1*16) by sequence specific primers in RA patients. Comparison of HLA DR beta 1 allele frequencies between patients and control groups was made using Pearson's chi-square test to find possible association of HLA DR?1 alleles with RA in Pakistani rheumatoid patients. Results: HLA DR beta 1*04 was expressed with significantly increased frequency in patients with rheumatoid arthritis (p <0.05). HLA DR?1*11 was expressed statistically significantly more in control group as compared to rheumatoid patients indicating a possible protective effect. There was no statistically significant difference observed in frequencies of HLA DR beta 1 allele *01, DR beta 1 allele *03, DR beta 1 allele *07, DR beta 1 allele *08, DR beta 1 allele *09, DR beta 1 allele *10, DR beta 1 allele *12, DR beta 1 allele *13, DR beta 1 allele *14, DR?1 allele *15 and DR beta 1 allele *16 between patients and control groups. Conclusion: The identification of susceptible HLA DR beta 1 alleles in Pakistani RA patients may help physicians to make early decisions regarding initiation of early intensive therapy with disease modifying anti rheumatic medicines and biological agents decreasing disability in RA patients. (author)

FOREWORD: Dr Trevor J Hicks Dr Trevor J Hicks

Science.gov (United States)

Goossens, Darren

2009-03-01

This issue of Journal of Physics: Condensed Matter has been assembled to recognize the valuable contribution of Dr Trevor J Hicks to the field of neutron scattering and magnetism. Trevor began his study of magnetism as a PhD student at Monash University in Melbourne in the early 1960s, working with Professor Jack Smith. From the very beginning magnetism in alloys, and disordered systems in general, became a key aspect of his career. After a postdoctoral position at Harwell working with Dr Graeme Low Trevor returned to Australia and took up a position with Monash. He soon became a key figure in developing the capability for neutron scattering using the HIFAR reactor at the Australian Atomic Energy Commission, now the Australian Nuclear Science and Technology Organisation, ANSTO. The instrumentation was always developed to further his studies of magnetism. The development of polarization analysis measurements of diffuse magnetic scattering, first using iron filters and then his own design of supermirror benders for beam polarization, took place through the 1970s, 1980s and into the 1990s. Throughout this time, Trevor mentored a series of PhD students and postdoctoral fellows, many of whom have contributed to this issue (and, indeed, guest edited it). As befits a scientist and university academic for whom teaching has always been important, Trevor has not only created a strong body of significant research, he has also made a major contribution to preparing several generations of neutron scattering scientists, and this issue reflects that. When I approached Journal of Physics: Condensed Matter with a proposal for an issue in honour of Trevor, the response was immediate and positive. It is with great pleasure that I present the result of that proposal. The great diversity of the content, all centred on neutron scattering and magnetism, reflects the breadth of Trevor's own career and of the scientists with whom he has interacted. Finally, I would like to make some

Comparaison du Srōš Drōn avec le Drōn Yašt

OpenAIRE

Redard, Céline

2015-01-01

This paper draws a parallel between two texts having the same textual base: The Srōš Drōn, derived from the Long Liturgy and the Drōn Yašt, belonging to the short liturgies. The goal is to establish the similarities and the discrepancies between these two texts. Peer reviewed

Principles of plastic surgery portrayed by the professional life of Dr John Peter Mettauer.

Science.gov (United States)

Avashia, Yash J; Thaller, Seth R

2011-11-01

Regarded as "America's first plastic surgeon," Dr John Peter Mettauer's professional life displays 3 fundamental keystones of plastic surgery: education, innovation, and practice. To fully appreciate the history of our plastic surgery, one must look beyond a purely factual recount of noteworthy actions performed decades ago. Fundamental principles that governed achievements of our predecessors remain applicable even today. Dr Mettauer thrived as a medical student under the influence of distinguished professors in medicine at the University of Pennsylvania. Later, he continued to propagate their basic tenets when he established his medical institute in 1837. Throughout his life, Dr Mettauer combined ingenuity with scientific inquiry to devise numerous unprecedented surgical techniques and instruments. He was a prolific writer and exquisitely documented his work in medical journals for the benefit of both contemporary and future surgeons. One of Dr Mettauer's momentous achievements in plastic surgery that displays his remarkable capabilities was his contributions to management of both simple and complicated cases of cleft palate. He was the first to describe relaxing lateral incisions for treating complete cleft palates and, incidentally, was the first to successfully treat this in America. He invariably replicated similar success in establishing techniques for treating a wide range of anatomic deformities. Cumulatively, Dr Mettauer's lifelong commitment and diligence have truly laid a foundation for the eventual progress and success in the field of plastic surgery.

Association of differentiated thyroid carcinoma with HLA-DR7

International Nuclear Information System (INIS)

Sridama, V.; Hara, Y.; Fauchet, R.; DeGroot, L.J.

1985-01-01

Seventy-four American white thyroid cancer patients were typed for HLA-A, B, and DR antigens. A significant increase in HLA-DR7 was found in the nonradiation-associated thyroid cancer patients (42.5%, 20/47 cases), compared to 22.8% of 979 normal controls. The association is stronger in the follicular and mixed papillary-follicular subgroup (52.0%, 13/25 cases, P corrected less than 0.01). The occurrence of various malignancies in family members was found in 57.9% of HLA-DR7 positive patients, versus 20% of HLA-DR7 negative patients, in a retrospective record review. Although the frequency of HLA-DR7 was not increased in the radiation-associated thyroid cancer patients (22.2%, 6/27 cases), the interval from the irradiation date to the onset date of thyroid cancer was shorter in HLA-DR7 positive cases (17.3 +/- 6.2 years) than in HLA-DR7 negative patients (29.4 +/- 11.5 years). This data suggest that HLA-DR7 is associated with and may influence development of thyroid cancer

Promosi Manajemen Nyeri Nonfarmakologi Oleh Keluarga Pada Pasien Post Operasi Di Ruang BCH RSUPN Dr.Ciptomangun Kusumo Jakarta

OpenAIRE

Ilmiasih, Reni

2013-01-01

Promosi Manajemen Nyeri Nonfarmakologi oleh Keluarga pada Pasien Post Operasi di Ruang BCH RSUPN Dr.Ciptomangun Kusumo JakartaNonpharmacological Pain Management Promotion by family to the Post Surgery Patients in BCH Ward of RSUPN Dr.Ciptomangun Kusumo JakartaReni IlmiasihFakultas Ilmu Kesehatan Universitas Muhammadiyah MalangJl. Bendungan Sutami 188A Malang 65145E-mail : anajemen nyeri non farmakologi perlu dilakukan oleh perawat di ruang bedah meskipun sering d...

Dr. Martin Luther King, Jr. as Spiritual Leader

Directory of Open Access Journals (Sweden)

Andrea Pierce

2013-09-01

Full Text Available The purpose of this paper is to explore Dr. Martin Luther King Jr.’s spiritual leadership through his “I Have a Dream” speech. The paper explores the three characteristics of spiritual leadership as posed by Fry’s (2003 spiritual leadership theory: vision, hope/faith and altruistic love. The research draws upon these characteristics through qualitative content analysis of Dr. Martin Luther King Jr.’s “I Have a Dream” speech to illustrate Dr. King’s leadership as that of a spiritual leader. The research advances the spiritual leadership theory by establishing Dr. Martin Luther King Jr. as a spiritual leader. Through the illustration of Dr. King’s spiritual leadership, the characteristics of a spiritual leader are given tangible understanding.

The DR-2 project

DEFF Research Database (Denmark)

Ølgaard, Povl Lebeck

2003-01-01

state of the reactor and to determine, which radionuclides remain where in the reactor in what amounts. The first part of the reactor to be investigated was the reactor tank. The lids at the reactor top wereremoved, air samples taken and smear test made in the tank. Then the control rods, the magnet....... At the start of the project the activity in DR-2 was about 45-50 GBq. Now it is about 5-10 GBq. Based on the results of the DR-2 project it is believed that the reactor can readily bedismantled and decommissioned....

Open standards for cascade models for RHIC: Volume 1. Proceedings of RIKEN BNL Research Center workshop

International Nuclear Information System (INIS)

1997-01-01

It is widely recognized that cascade models are potentially effective and powerful tools for interpreting and predicting multi-particle observables in heavy ion physics. However, the lack of common standards, documentation, version control, and accessibility have made it difficult to apply objective scientific criteria for evaluating the many physical and algorithmic assumptions or even to reproduce some published results. The first RIKEN Research Center workshop was proposed by Yang Pang to address this problem by establishing open standards for original codes for applications to nuclear collisions at RHIC energies. The aim of this first workshop is: (1) to prepare a WWW depository site for original source codes and detailed documentation with examples; (2) to develop and perform standardized test for the models such as Lorentz invariance, kinetic theory comparisons, and thermodynamic simulations; (3) to publish a compilation of results of the above work in a journal e.g., ''Heavy Ion Physics''; and (4) to establish a policy statement on a set of minimal requirements for inclusion in the OSCAR-WWW depository

Tribute to Dr Jacques Rogge

DEFF Research Database (Denmark)

Bourgois, Jan G; Dumortier, Jasmien; Callewaert, Margot

2017-01-01

'A tribute to Dr J. Rogge' aims to systematically review muscle activity and muscle fatigue during sustained submaximal quasi-isometric knee extension exercise (hiking) related to Olympic dinghy sailing as a tribute to Dr Rogge's merits in the world of sports. Dr Jacques Rogge is not only...... of invasive needle electromyography (EMG) during a specific sailing technique (hiking) on a self-constructed sailing ergometer. Hiking is a bilateral and multi-joint submaximal quasi-isometric movement which dinghy sailors use to optimize boat speed and to prevent the boat from capsizing. Large stresses...... are generated in the anterior muscles that cross the knee and hip joint, mainly employing the quadriceps at an intensity of 30-40% maximal voluntary contraction (MVC), sometimes exceeding 100% MVC. Better sailing level is partially determined by a lower rate of neuromuscular fatigue during hiking and for ≈60...

DR services in Fiji: attitudes, barriers and screening practices

Directory of Open Access Journals (Sweden)

Bridget Kool

2015-06-01

Full Text Available The aim of this study was to describe the attitudes and perceptions of primary health care doctors in Fiji regarding the importance of eye care in diabetes mellitus (DM management, to explore current eye care practice, and to investigate awareness and use of relevant clinical practice guidelines. The study builds on earlier research conducted in Fiji that identified a rapid increase of late-stage DR patients presenting for treatment, at a time when surgery was the only option.

Human immune responsiveness to Lolium perenne pollen allergen Lol p III (rye III) is associated with HLA-DR3 and DR5.

Science.gov (United States)

Ansari, A A; Freidhoff, L R; Meyers, D A; Bias, W B; Marsh, D G

1989-05-01

A well-characterized allergen of Lolium perenne (perennial rye grass) pollen, Lol p III, has been used as a model antigen to study the genetic control of the human immune response. Associations between HLA type and IgE or IgG antibody (Ab) responsiveness to Lol p III were studied in two groups of skin-test-positive Caucasoid adults (N = 135 and 67). We found by nonparametric and parametric analyses that immune responsiveness to Lol p III was significantly associated with HLA-DR3 and DR5. No association was found between any DQ type and immune responsiveness to Lol p III. Geometric mean IgE or IgG Ab levels to Lol p III were not different between B8+, DR3+ subjects and B8-, DR3+ subjects, showing that HLA-B8 had no influence on the association. Lol p III IgG Ab data obtained on subjects after grass antigen immunotherapy showed that 100% of DR3 subjects and 100% of DR5 subjects were Ab+. A comparison of all the available protein sequences of DRB gene products showed that the first hypervariable region of DR3 and DR5 (and DRw6), and no other region, contains the sequence Glu9-Tyr-Ser-Thr-Ser13. Our observations are consistent with the possibility that immune responsiveness to the allergen Lol p III is associated with this amino acid sequence in the first hypervariable region of the DR beta 1 polypeptide chain.

105-DR Large Sodium Fire Facility closure plan. Revision 1

Energy Technology Data Exchange (ETDEWEB)

1993-05-01

The Hanford Site, located northwest of the city of Richland, Washington, houses reactors, chemical-separation systems, and related facilities used for the production of special nuclear materials, and activities associated with nuclear energy development. The 105-DR Large Sodium Fire Facility (LSFF), which was in operation from about 1972 to 1986, was a research laboratory that occupied the former ventilation supply room on the southwest side of the 105-DR Reactor facility. The LSFF was established to provide a means of investigating fire and safety aspects associated with large sodium or other metal alkali fires in the liquid metal fast breeder reactor (LMFBR) facilities. The 105-DR Reactor facility was designed and built in the 1950`s and is located in the 100-D Area of the Hanford Site. The building housed the 105-DR defense reactor, which was shut down in 1964. The LSFF was initially used only for engineering-scale alkali metal reaction studies. In addition, the Fusion Safety Support Studies program sponsored intermediate-size safety reaction tests in the LSFF with lithium and lithium lead compounds. The facility has also been used to store and treat alkali metal waste, therefore the LSFF is subject to the regulatory requirements for the storage and treatment of dangerous waste. Closure will be conducted pursuant to the requirements of the Washington Administrative Code (WAC) 173-303-610. This closure plan presents a description of the facility, the history of waste managed, and the procedures that will be followed to close the LSFF as an Alkali Metal Treatment Facility. No future use of the LSFF is expected.

New knowledge network evaluation method for design rationale management

Science.gov (United States)

Jing, Shikai; Zhan, Hongfei; Liu, Jihong; Wang, Kuan; Jiang, Hao; Zhou, Jingtao

2015-01-01

Current design rationale (DR) systems have not demonstrated the value of the approach in practice since little attention is put to the evaluation method of DR knowledge. To systematize knowledge management process for future computer-aided DR applications, a prerequisite is to provide the measure for the DR knowledge. In this paper, a new knowledge network evaluation method for DR management is presented. The method characterizes the DR knowledge value from four perspectives, namely, the design rationale structure scale, association knowledge and reasoning ability, degree of design justification support and degree of knowledge representation conciseness. The DR knowledge comprehensive value is also measured by the proposed method. To validate the proposed method, different style of DR knowledge network and the performance of the proposed measure are discussed. The evaluation method has been applied in two realistic design cases and compared with the structural measures. The research proposes the DR knowledge evaluation method which can provide object metric and selection basis for the DR knowledge reuse during the product design process. In addition, the method is proved to be more effective guidance and support for the application and management of DR knowledge.

Implementing Python for DrRacket

OpenAIRE

Ramos, Pedro Palma; Leitão, António Menezes

2014-01-01

The Python programming language is becoming increasingly popular in a variety of areas, most notably among novice programmers. On the other hand, Racket and other Scheme dialects are considered excellent vehicles for introducing Computer Science concepts. This paper presents an implementation of Python for Racket and the DrRacket IDE. This allows Python programmers to use Racket libraries and vice versa, as well as using DrRacket's pedagogic features. In particular, it allows architects and d...

Brahm Prakash, Dr

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1972 Section: Engineering & Technology. Brahm Prakash, Dr Ph.D. (Panjab), FNA 1974-76. Date of birth: 21 August 1912. Date of death: 3 January 1984. Specialization: Metallurgy. YouTube; Twitter; Facebook; Blog ...

Dr. David Syz, State Secretary for Economic Affairs, Switzerland

CERN Multimedia

Maximilien Brice

2003-01-01

Dr. David Syz, State Secretary for Economic Affairs, Switzerland, toured the assembly hall of the ATLAS experiment on a recent visit to CERN.Photos 01, 02: Dr. Peter Jenni, spokesperson for the ATLAS experiment (second from left), explains to Dr. David Syz (fourth from left) and accompanying visitors the process of integration of a 26-metre-long coil of the barrel toroid magnet system into its coil casing.Photo 03: Dr. Peter Jenni (extreme right) with Dr. David Syz (front row, fourth from right) behind a stack of 26-metre-long 'racetrack' coils awaiting integration into their coil casings.

Hazarika, Dr Nabajit

Indian Academy of Sciences (India)

Hazarika, Dr Nabajit Ph.D. (Tezpur). Date of birth: 17 January 1986. Specialization: Remote Sensing, GIS Applications, Fluvial Geomorphology, Landuse Landcover Studies Address: Dept. of Environmental Science, Nagaland University, Lumami 798 627, Nagaland Contact: Residence: 94354 81256, 97066 71256

Prakash, Dr Vishweshwaraiah

Indian Academy of Sciences (India)

Prakash, Dr Vishweshwaraiah Ph.D. (Mysore), FNASc, FNAE, FRSC,FNAAS. Date of birth: 23 November 1951. Specialization: S&T Policy, Physical Biochemistry, Chemistry of Macromolecules, Biophysics of Proteins, Enzymes & Thermodynamics, Food Chemistry, Nutrition, Food Biotechnology and Food Science Address: ...

Dikshit, Dr Madhu

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 2000 Section: Medicine. Dikshit, Dr Madhu Ph.D. (Kanpur), FNASc, FNA Council Service: 2016. Date of birth: 21 November 1957. Specialization: Redox Biology, Cardiovascular Pharmacology, Molecular Pharmacology, Neutrophiles and Nitric Oxide Synthase Address: Department ...

Sethunathan, Dr Nambrattil

Indian Academy of Sciences (India)

Fellow Profile. Elected: 1986 Section: Plant Sciences. Sethunathan, Dr Nambrattil Ph.D. (Madras), FNA, FNAAS, FNASc. Date of birth: 2 June 1937. Specialization: Environmental Microbiology Address: Flat No. 103, Ushodaya Apartments, Sri Venkateswara Officers' Colony, Ramakrishnapuram, Secunderabad 500 056, A.P.

Mukerji, Dr Mitali

Indian Academy of Sciences (India)

Elected: 2014 Section: Medicine. Mukerji, Dr Mitali Ph.D. (IISc). Date of birth: 13 November 1967. Specialization: Functional Genomics, Population Genomics, Ayurgenomics Address: Sr Principal Scientist, Genomics & Molecualr Medicine, Institute of Genomics & Integrative Biology, Sukhdev Vihar, Mathura Road, New Delhi ...

Dr. Hans Chang, Director, Physics Research Committee, Stichting voor Fundamenteel Onderzoek der Materie (FOM), Dr. Joris Van Enst, Head of Science Policy Division, Ministry of Education, Culture and S cience, Dr. Jan Bezemer, NL Delegate CERN, Netherlands

CERN Multimedia

Patrice Loiez

1999-01-01

Dr. Hans Chang, Director, Physics Research Committee, Stichting voor Fundamenteel Onderzoek der Materie (FOM), Dr. Joris Van Enst, Head of Science Policy Division, Ministry of Education, Culture and S cience, Dr. Jan Bezemer, NL Delegate CERN, Netherlands

Mukhopadhyay, Dr Sangita

Indian Academy of Sciences (India)

Elected: 2013 Section: Medicine. Mukhopadhyay, Dr Sangita Ph.D. (Utkal), FNASc. Date of birth: 1 January 1966. Specialization: Immunology, Cell Signalling, Communicable Diseases Address: Group Leader, Molecular Cell Biology, Centre for DNA Fingerprinting & Diagnostics, Nampally, Hyderabad 500 001, A.P.. Contact ...

Mohanty, Dr Debasisa

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 2012 Section: General Biology. Mohanty, Dr Debasisa Ph.D. (IISc), FNASc, FNA. Date of birth: 30 November 1966. Specialization: Bioinformatics, Computational & Structural Biology, Biophysics Address: National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110 067, ...

Banerjee, Dr Srikumar

Indian Academy of Sciences (India)

Fellow Profile. Elected: 1990 Section: Engineering & Technology. Banerjee, Dr Srikumar Ph.D. (IIT, Kharagpur), FNA, FNAE, FNASc, FTWAS Council Service: 2007-12; Vice-President: 2010-12. Date of birth: 25 April 1946. Specialization: Materials Science, Physical Metallurgy, Phase Transformations, Nuclear Fuel Cycle, ...

Authikesavalu, Dr Munisamy

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1948 Section: Medicine. Authikesavalu, Dr Munisamy MBBS (Madras), MS (Minneapolis), FRCS. Date of birth: 16 August 1906. Date of death: 22 September 1973. Specialization: Experimental Surgery, Ophthalmology, Otolaryngology Last known address: 5-C, Lavelle Cross Road, ...

Amarjit Singh, Dr

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1974 Section: Engineering & Technology. Amarjit Singh, Dr Ph.D. (Harvard). Date of birth: 19 November 1924. Specialization: Millimeter Wave Tubes, Microwave Tubes and Microwave Electronics Address: 12, Auburn Court, Vernon Hills, IL 60061, USA Contact: Residence: ...

Chandy, Dr Mammen

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 2008 Section: Medicine. Chandy, Dr Mammen MD (Madras), FRACP, FRCPA. Date of birth: 30 August 1949. Specialization: Hematology, Bone Marrow Transplantation and Molecular Genetics of Blood Diseases Address: Director, Tata Memorial Centre, 14, Major Arterial Road, ...

Shivaji, Dr Sisinthy

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 2011 Section: Animal Sciences. Shivaji, Dr Sisinthy Ph.D. (Delhi), FNASc. Date of birth: 17 June 1950. Specialization: Anti-Microbial Resistance, Gut Microbiome, Eye Disease, Conservation Biology, Mammalian Sperm Function, Bacterial Biodiversity of Cold Habitats, Cold ...

Potensi dan Efektivitas Pemungutan Retribusi RSUD Dr. Agoesdjam Ketapang

OpenAIRE

B61110063, JAMALUDIN

2014-01-01

This study entitled Potential and Effectiveness of retribution collecting in RSUD Dr. Agoesdjam Ketapang which aims to identify and analyze the potential retribution of RSUD Dr . Agoesdjam and also to investigate and analyze the effectiveness of the retribution collecting in RSUD Dr. Agoesdjam . This study uses secondary data , from 2008 to 2012 that were obtained from the Regional Revenue Office of Ketapang and RSUD Dr. Agoesdjam Ketapang . The method of this study is descriptive. To analyz...

MSeqDR: A Centralized Knowledge Repository and Bioinformatics Web Resource to Facilitate Genomic Investigations in Mitochondrial Disease.

Science.gov (United States)

Shen, Lishuang; Diroma, Maria Angela; Gonzalez, Michael; Navarro-Gomez, Daniel; Leipzig, Jeremy; Lott, Marie T; van Oven, Mannis; Wallace, Douglas C; Muraresku, Colleen Clarke; Zolkipli-Cunningham, Zarazuela; Chinnery, Patrick F; Attimonelli, Marcella; Zuchner, Stephan; Falk, Marni J; Gai, Xiaowu

2016-06-01

MSeqDR is the Mitochondrial Disease Sequence Data Resource, a centralized and comprehensive genome and phenome bioinformatics resource built by the mitochondrial disease community to facilitate clinical diagnosis and research investigations of individual patient phenotypes, genomes, genes, and variants. A central Web portal (https://mseqdr.org) integrates community knowledge from expert-curated databases with genomic and phenotype data shared by clinicians and researchers. MSeqDR also functions as a centralized application server for Web-based tools to analyze data across both mitochondrial and nuclear DNA, including investigator-driven whole exome or genome dataset analyses through MSeqDR-Genesis. MSeqDR-GBrowse genome browser supports interactive genomic data exploration and visualization with custom tracks relevant to mtDNA variation and mitochondrial disease. MSeqDR-LSDB is a locus-specific database that currently manages 178 mitochondrial diseases, 1,363 genes associated with mitochondrial biology or disease, and 3,711 pathogenic variants in those genes. MSeqDR Disease Portal allows hierarchical tree-style disease exploration to evaluate their unique descriptions, phenotypes, and causative variants. Automated genomic data submission tools are provided that capture ClinVar compliant variant annotations. PhenoTips will be used for phenotypic data submission on deidentified patients using human phenotype ontology terminology. The development of a dynamic informed patient consent process to guide data access is underway to realize the full potential of these resources. © 2016 WILEY PERIODICALS, INC.

Dr. Irene Sänger-Bredt, a life for astronautics

Science.gov (United States)

Zaganescu, Nicolae-Florin

2004-12-01

Irene Bredt (b.1911 at Bonn) obtained her Doctorate in Physics in 1937; in the same year she became a scientific researcher at the German Research Center for Aviation at Trauen, led by Prof. Dr. Eugen Sänger. Soon, the young but efficient Dr. Irene Bredt became the first assistant of Dr. Sänger, who married her (1951). During 1973-1978, Dr. Bredt was in correspondence with Prof. Dr. Nikolae-Florin Zaganescu and helped him to familiarize the Romanian readers with Prof. Sänger's life and achievements. As for Dr. Bredt's life, she specified three main periods of her activity: 1937-1942, when she was researcher in charge of thermodynamic problems of liquid-fuelled rocket engines at Trauen 1942-1945, when she was Senior Researcher in charge of Ramjet in flight performances at Ainring, and also coauthored the Top Secret Technical report entitled 'A Rocket Engine for a Long-Range Bomber', which was finished in 1941 but edited only in 1944 the post world war II period, when she was Scientific Advisor or Director at various civil and military research institutes, universities, etc. Dr. Irene Sänger-Bredt helped her husband to develop many scientific theories like Ramjet thermodynamic theory, and photon rocket theory and also in establishing IAF and IAA. In 1970, Dr. Irene Sänger-Bredt was honored with 'Hermann Oberth Gold Medal' for her impressive scientific activity.

Professor Bakytzhan Abdiraiym Rector of the L. Gumilov Eurasian National University, Astana, Kazakhstan accompanied by Prof. Kairat Kuterbekov, Dr Bekzat Prmantayeva, Dr Kuralay Maksut with the Director-General, Dr Tadeusz Kurtyka, Adviser for Non-Member States, Mrs Julia Andreeva, Department of Information Technologies and Dr Nikolai Zimine, ATLAS Collaboration, Joint Institute for Nuclear Research, Dubna

CERN Document Server

Maximilien Brice

2011-01-01

Professor Bakytzhan Abdiraiym Rector of the L. Gumilov Eurasian National University, Astana, Kazakhstan accompanied by Prof. Kairat Kuterbekov, Dr Bekzat Prmantayeva, Dr Kuralay Maksut with the Director-General, Dr Tadeusz Kurtyka, Adviser for Non-Member States, Mrs Julia Andreeva, Department of Information Technologies and Dr Nikolai Zimine, ATLAS Collaboration, Joint Institute for Nuclear Research, Dubna

Chaddah, Dr Praveen

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1993 Section: Physics. Chaddah, Dr Praveen Ph.D. (Mumbai), FNA, FNASc. Date of birth: 20 December 1951. Specialization: Superconductivity, Low Temperature Physics and Phase Transitions Address: Flat 702, Block 24, Heritage City, MG Road (near Metro Station), Gurgaon ...

Ranganathan, Dr Darshan

Indian Academy of Sciences (India)

Elected: 1991 Section: Chemistry. Ranganathan, Dr Darshan Ph.D. (Delhi), FNA. Date of birth: 4 June 1941. Date of death: 4 June 2001. Specialization: Organic Chemistry, Bio-Organic Chemistry and Supramolecular Chemistry Last known address: Scientist, Indian Institue of Chemical, Technology, Uppal Road, Hyderabad ...

Description of Work for Borehole Sampling at the 116-DR-1and 116-DR-2 Trenches

International Nuclear Information System (INIS)

Bergstrom, K. A.

1999-01-01

This description of work (DOW) details the sampling and analysis activities for characterizing the deep zone soils below the 116-DR-1and 116-DR-2 trenches, which are located in the 100-DR- 1 Operable Unit (OU), and will serve as a guide for the personnel performing the work. The ''deep zone'' refers to the portion of the vadose zone between the bottom of the waste site and the water table. The scope of work includes drilling a borehole (B8786), sampling vadose zone and upper saturated zone soils at ∼ 1-m intervals, collecting a water sample below the top of the water table, and analyzing the samples for all contaminants of concern (COCs). Specific procedures for defined tasks are covered under the Bechtel Hanford, Inc. (BHI)manual, BHI-EE-01, Environmental Investigations Procedures

Goldie Brangman Remembers the Operation to Save Dr King.

Science.gov (United States)

Koch, Evan; Brangman, Goldie

2015-12-01

In September 1958 the Rev Dr Martin Luther King Jr was stabbed and nearly assassinated. Surgeons at Harlem Hospital in New York City removed a 17.8-cm (7-in)-long letter opener from Dr King's chest. Certified Registered Nurse Anesthetist Goldie Brangman remembers this event because she participated in Dr King's anesthetic. This article correlates Brangman's memories with published accounts of the event. It also places the event within the context of the modern civil rights movement that Dr King led.

Effect of minimum strength of mirror magnetic field (Bmin) on production of highly charged heavy ions from RIKEN liquid-He-free super conducting electron-cyclotron resonance ion source (RAMSES)

International Nuclear Information System (INIS)

Arai, Hideyuki; Imanaka, Masashi; Lee, S.-M.Sang-Moo; Higurashi, Yoshihide; Nakagawa, Takahide; Kidera, Masanori; Kageyama, Tadashi; Kase, Masayuki; Yano, Yasushige; Aihara, Toshimitsu

2002-01-01

We measured the beam intensity of highly charged heavy ions (O, Ar and Kr ions) as a function of the minimum strength of mirror magnetic field (B min ) of the RIKEN liquid-He-free super conducting electron-cyclotron resonance ion source. In this experiment, we found that the optimum value of B min exists to maximize the beam intensity of highly charged heavy ions and the value was almost the same (∼0.49 T) for various charge state heavy ions

Dr. Steve Thompson, Chief Executive, The Royal Society of New Zealand

CERN Multimedia

Maximilien Brice

2002-01-01

L. to r.: Dr Austin Ball, Deputy Technical Coordinator, CMS experiment; Dr Roland Horisberger, Paul Scherrer Institute and CERN, CMS experiment; Dr Steve Thompson, Chief Executive, The Royal Society of New Zealand; Dr Michel Della Negra, Spokesman, CMS experiment and Dr Alick Macpherson, Paul Scherrer Institute and CERN, CMS experiment, in the CMS Silicon Tracker assembly hall.

Demonstration of automated price response in large customers in New York City using Auto-DR and OpenADR

Energy Technology Data Exchange (ETDEWEB)

Kim, Joyce Jihyun [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Schetrit, Oren [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Yin, Rongxin [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Kiliccote, Sila [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

2014-05-01

Demand response (DR) – allowing customers to respond to reliability requests and market prices by changing electricity use from their normal consumption pattern – continues to be seen as an attractive means of demand-side management and a fundamental smart-grid improvement that links supply and demand. From October 2011 to December 2013, the Demand Response Research Center at Lawrence Berkeley National Laboratory, the New York State Energy Research and Development Authority, and partners Honeywell and Akuacom, have conducted a demonstration project enabling Automated Demand Response (Auto-DR) in large commercial buildings located in New York City using Open Automated Demand Response (OpenADR) communication protocols. In particular, this project focuses on demonstrating how the OpenADR platform, enabled by Akuacom, can automate and simplify interactions between buildings and various stakeholders in New York State and enable the automation of customers’ price response to yield bill savings under dynamic pricing. In this paper, the cost control opportunities under day-ahead hourly pricing and Auto-DR control strategies are presented for four demonstration buildings; present the breakdown of Auto-DR enablement costs; summarize the field test results and their load impact; and show potential bill savings by enabling automated price response under Consolidated Edison’s Mandatory Hourly Pricing (MHP) tariff. For one of the sites, the potential bill savings at the site’s current retail rate are shown. Facility managers were given granular equipment-level opt-out capability to ensure full control of the sites during the Auto-DR implementation. The expected bill savings ranged from 1.1% to 8.0% of the total MHP bill. The automation and enablement costs ranged from $70 to $725 per kW shed. The results show that OpenADR can facilitate the automation of price response, deliver savings to the customers and opt-out capability of the implementation retains control of the

Bhandari, Dr Nita

Indian Academy of Sciences (India)

Elected: 2015 Section: Medicine. Bhandari, Dr Nita Ph.D. (JNU), FAMS. Date of birth: 9 November 1955. Specialization: Nutrition-Infection Interaction, Child Health, Nutritional Interventions, Clinical Evaluation of Vaccine Address: President & Director, Centre for Health R&D Society for Applied Studies, 45, Kalu Sarai, New ...

Chandrasekaran, Dr Chidambara

Indian Academy of Sciences (India)

Fellow Profile. Elected: 1945 Section: Mathematical Sciences. Chandrasekaran, Dr Chidambara Ph.D. (London) 1962-64. Date of birth: 30 October 1911. Date of death: 4 January 2000. Specialization: Statistics, Public Health and Demography Last known address: 'Sri Kripa', 79/3, Benson Cross Road, Bengaluru 560 046.

Mukhopadhyay, Dr Amitabha

Indian Academy of Sciences (India)

Fellow Profile. Elected: 2010 Section: General Biology. Mukhopadhyay, Dr Amitabha Ph.D. (Jadavpur), FNASc, FNA. Date of birth: 5 February 1959. Specialization: Cell Biology, Host-Pathogen Interactions, Drug Delivery Address: Staff Scientist VII, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110 067, ...

Chandy, Dr Jacob

Indian Academy of Sciences (India)

Elected: 1961 Section: Medicine. Chandy, Dr Jacob MBBS (Madras), FRCS (c) Council Service: 1962-70. Date of birth: 23 January 1910. Date of death: 23 June 2007. Specialization: Neurology, Neurosurgery and Medical Education Last known address: Paarra, Matteethra, Kottayam 686 004. YouTube; Twitter; Facebook ...

Adhya, Dr Samit

Indian Academy of Sciences (India)

Elected: 1999 Section: General Biology. Adhya, Dr Samit Ph.D. (New York), FNA. Date of birth: 29 September 1953. Specialization: Mitochondrial Biology, Molecular Genetics of Parasites, Intracellular RNA Trafficking and DNA Diagnostics Address: CSIR Emeritus Scientist, Indian Inst. of Chemical Biology, 4, Raja S.C. ...

Proceedings of the 5th workshop of 'quantum complex phenomena, -superconductivity, magnetism and phonon-' under the NIMS-RIKEN-JAEA cooperative research program on quantum beam science and technology

International Nuclear Information System (INIS)

Shamoto, Shin-ichi; Kodama, Katsuaki

2012-08-01

The 5th workshop of the NIMS-RIKEN-JAEA Cooperative Research Program 'Quantum Complex Phenomena, -Superconductivity, Magnetism and Phonon-' was held on January 23-24, 2012 at KKR Hakone Miyanoshita. This workshop is aimed to reveal the mechanism of quantum complex phenomena for the developments of next generation functional materials on the basis of 'Joint Research Agreement for the Pioneering R and D with Quantum Beam Technology' concluded by NIMS, RIKEN and JAEA on December 20, 2006. The neutron facilities in Tokai, i.e., the research reactor JRR-3 and the proton accelerator J-PARC (Japan Proton Accelerator Research Complex), were damaged by the Tohoku-Kanto earthquake on March 11, 2011. J-PARC members' devoted efforts for the recovery made it possible to successfully produce neutron beam in the midnight of January 24, just after this workshop. Also at JRR-3 all the repair works of the reactor facilities and buildings have been completed by the end of the fiscal year 2011. Yet, the safety analysis report is to be submitted and after its positive review by the national regulatory authority, the JRR-3 can undergo the regular periodic inspection to resume its operation. Under this circumstance, characteristic technologies, instruments, and distinguished researches of each institute about 'Superconductivity, Magnetism and Phonon' are introduced and discussed in addition to research outcomes of this Joint Research Agreement including a future prospect of this research area. This report includes abstracts and materials of the presentations in the workshop. (author)

HLA-DR expression and disease activity in ulcerative colitis

DEFF Research Database (Denmark)

Poulsen, L O; Elling, P; Sørensen, Flemming Brandt

1986-01-01

and 3 months later. The rectal epithelial cells were HLA-DR-positive in all patients at the first two examinations. After 3 months five patients had changed to an HLA-DR-negative stage, whereas the other seven patients remained HLA-DR-positive. Closer analyses showed that expression/nonexpression of HLA...

105-DR Large Sodium Fire Facility Supplemental Information to the Hanford Facility Contingency Plan (DOE/RL-93-75)

International Nuclear Information System (INIS)

Edens, V.G.

1998-05-01

This document is a unit-specific contingency plan for the 105-DR Large Sodium Fire Facility and is intended to be used as a supplement to DOE/RL-93-75, Hanford Facility Contingency Plan (DOE-RL 1993). This unit-specific plan is to be used to demonstrate compliance with the contingency plan requirements of Washington Administrative Code (WAC) 173-303 for certain Resource Conservation and Recovery Act of 1976 (RCRA) waste management units.The LSFF occupied the former ventilation supply fan room and was established to provide a means of investigating fire and safety aspects associated with large sodium or other metal alkali fires. The unit was used to conduct experiments for studying the behavior of molten alkali metals and alkali metal fires. This unit had also been used for the storage and treatment of alkali metal dangerous waste. Additionally, the Fusion Safety Support Studies programs sponsored intermediate-size safety reaction tests in the LSFF with lithium and lithium-lead compounds. The LSFF, which is a RCRA site, was partially clean closed in 1995 and is documented in 'Transfer of the 105-DR Large Sodium Fire Facility to Bechtel Hanford, Inc.' (BHI 1998). In summary, the 105-DR supply fan room (1720-DR) has been demolished, and a majority of the surrounding soils were clean-closed. The 117-DR Filter Building, 116-DR Exhaust Stack, 119- DR Sampling Building, and associated ducting/tunnels were not covered under this closure

HLA-DR-expressing cells and T-lymphocytes in sural nerve biopsies

DEFF Research Database (Denmark)

Schrøder, H D; Olsson, T; Solders, G

1988-01-01

was confirmed. HLA-DR expression was found in all biopsies and thus was not restricted to any particular type of neuropathy. The HLA-DR expression appeared to correlate with severity and activity of the neuropathy. HLA-DR-expressing macrophages wrapping myelinated fibers were prominent in primary demyelinating......Thirty-five sural nerve biopsies were stained immunohistochemically for HLA-DR antigen. HLA-DR was expressed on nonmyelinating Schwann cells, macrophages, vascular endothelium, and perineurium. By means of double immunofluorescence staining the identity of the HLA-DR presenting structures...

Varadarajan, Dr Srinivasan

Indian Academy of Sciences (India)

Elected: 1972 Section: Chemistry. Varadarajan, Dr Srinivasan Ph.D. (Delhi and Cantab), D.Sc. (h.c.), D.Litt. (h.c.), FNA, FNAE, FTWAS Council Service:1974-88; Vice-President: 1977-79; President: 1980-82. Date of birth: 31 March 1928. Specialization: Organic & Biological Chemistry, Molecular Biology, Engineering Design ...

Sengupta, Dr Sagar

Indian Academy of Sciences (India)

Sengupta, Dr Sagar Ph.D. (IISc), FNA, FNASc. Date of birth: 23 June 1968. Specialization: Cancer Biology, Cell Signalling, Mytochondrial Biology Address: National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110 067, U.T.. Contact: Office: (011) 2670 3786. Residence: (0124) 422 7107. Mobile: 93131 05470

Sengupta, Dr Sagar

Indian Academy of Sciences (India)

Fellow Profile. Elected: 2017 Section: General Biology. Sengupta, Dr Sagar Ph.D. (IISc), FNA, FNASc. Date of birth: 23 June 1968. Specialization: Cancer Biology, Cell Signalling, Mytochondrial Biology Address: National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110 067, U.T.. Contact: Office: (011) 2670 3786

Identification of "pathologs" (disease-related genes from the RIKEN mouse cDNA dataset using human curation plus FACTS, a new biological information extraction system

Directory of Open Access Journals (Sweden)

Socha Luis A

2004-04-01

Full Text Available Abstract Background A major goal in the post-genomic era is to identify and characterise disease susceptibility genes and to apply this knowledge to disease prevention and treatment. Rodents and humans have remarkably similar genomes and share closely related biochemical, physiological and pathological pathways. In this work we utilised the latest information on the mouse transcriptome as revealed by the RIKEN FANTOM2 project to identify novel human disease-related candidate genes. We define a new term "patholog" to mean a homolog of a human disease-related gene encoding a product (transcript, anti-sense or protein potentially relevant to disease. Rather than just focus on Mendelian inheritance, we applied the analysis to all potential pathologs regardless of their inheritance pattern. Results Bioinformatic analysis and human curation of 60,770 RIKEN full-length mouse cDNA clones produced 2,578 sequences that showed similarity (70–85% identity to known human-disease genes. Using a newly developed biological information extraction and annotation tool (FACTS in parallel with human expert analysis of 17,051 MEDLINE scientific abstracts we identified 182 novel potential pathologs. Of these, 36 were identified by computational tools only, 49 by human expert analysis only and 97 by both methods. These pathologs were related to neoplastic (53%, hereditary (24%, immunological (5%, cardio-vascular (4%, or other (14%, disorders. Conclusions Large scale genome projects continue to produce a vast amount of data with potential application to the study of human disease. For this potential to be realised we need intelligent strategies for data categorisation and the ability to link sequence data with relevant literature. This paper demonstrates the power of combining human expert annotation with FACTS, a newly developed bioinformatics tool, to identify novel pathologs from within large-scale mouse transcript datasets.

Gaia DR2 documentation Chapter 7: Variability

Science.gov (United States)

Eyer, L.; Guy, L.; Distefano, E.; Clementini, G.; Mowlavi, N.; Rimoldini, L.; Roelens, M.; Audard, M.; Holl, B.; Lanzafame, A.; Lebzelter, T.; Lecoeur-Taïbi, I.; Molnár, L.; Ripepi, V.; Sarro, L.; Jevardat de Fombelle, G.; Nienartowicz, K.; De Ridder, J.; Juhász, Á.; Molinaro, R.; Plachy, E.; Regibo, S.

2018-04-01

This chapter of the Gaia DR2 documentation describes the models and methods used on the 22 months of data to produce the Gaia variable star results for Gaia DR2. The variability processing and analysis was based mostly on the calibrated G and integrated BP and RP photometry. The variability analysis approach to the Gaia data has been described in Eyer et al. (2017), and the Gaia DR2 results are presented in Holl et al. (2018). Detailed methods on specific topics will be published in a number of separate articles. Variability behaviour in the colour magnitude diagram is presented in Gaia Collaboration et al. (2018c).

Jameel, Dr Shahid

Indian Academy of Sciences (India)

Jameel, Dr Shahid Ph.D. (Washington State Univ.), FNASc, FNA. Date of birth: 8 August 1957. Specialization: Molecular Biology and Molecular Virology Address: Chief Executive Officer, The Wellcome Trust/DBT India Alliance, 8-2-684/3/K/19, Kaushik Society, Road NO. 12, Banjara Hills, Hyderabad 500 034, A.P.. Contact:

Structure and management of tuberculosis control programs in fragile states--Afghanistan, DR Congo, Haiti, Somalia.

Science.gov (United States)

Mauch, Verena; Weil, Diana; Munim, Aayid; Boillot, Francois; Coninx, Rudi; Huseynova, Sevil; Powell, Clydette; Seita, Akihiro; Wembanyama, Henriette; van den Hof, Susan

2010-07-01

Health care delivery is particularly problematic in fragile states often connected with increased incidence of communicable diseases, among them tuberculosis. This article draws upon experiences in tuberculosis control in four fragile states from which four lessons learned were derived. A structured inventory to extract common themes specific for TB control in fragile states was conducted among twelve providers of technical assistance who have worked in fragile states. The themes were applied to the TB control programs of Afghanistan, DR Congo, Haiti and Somalia during the years 2000-2006. Case notifications and treatment outcomes have increased in all four countries since 2003 (treatment success rates 81-90%). Access to care and case detection however have remained insufficient (case detection rates 39-62%); There are four lessons learned: 1. TB control programs can function in fragile states. 2. National program leadership and stewardship are essential for quality and sustained TB control. 3. Partnerships with non-governmental providers are vital for continuous service delivery; 4. TB control programs in fragile states require consistent donor support. Despite challenges in management, coordination, security, logistics and funding, TB control programs can function in fragile states, but face considerable problems in access to diagnosis and treatment and therefore case detection. Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.

Dr. Albert Carr--Science Educator 1930-2000

Science.gov (United States)

Lopez, Leslie

2013-01-01

The very first issue of "Educational Perspectives" was published in October of 1962. Dr. Albert Carr wrote one of the inaugural essays on the topic of current developments in science education, and he went on to write several other articles for the journal. This article shares why Dr. Albert Carr's colleagues remember him for his…

A Tribute to Dr. Willy Lens

Directory of Open Access Journals (Sweden)

Maarten Vansteenkiste

2016-07-01

Full Text Available Dr. Willy Lens, born on December 10th, 1943, passed away on August 29th, 2014. With his passing, the motivation community has lost a seminal member, a mentor, and a friend. Dr. Lens – a Fellow of the Association for Psychological Science and Founding Fellow of the American Educational Research Association – made fundamental contributions to the study of motivation both through his own work and through his caring and thoughtful mentorship of a large community of scholars. With this tribute, we want to honor Dr. Willy Lens’ significance to psychology and education as well as his positive influence, both personally and professionally, on the lives of dozens of scholars. With his contagious enthusiasm and caring mentorship, Willy was an example for our academic community and with this tribute we express our gratitude for the privilege to have collaborated with him.

Drømmebilleder

DEFF Research Database (Denmark)

Fausing, Bent

2014-01-01

Bogen beskriver i en række intense analyser forbindelsen mellem ydre og indre billeder: altså mellem de moderne mediers billedverden og drømmens og erindringens indre billeder. I fokus for undersøgelsen er desuden kønnet, altså hvordan billeder viser, omformer eller skjuler kønnet, 'det andet', s...

Profile Interview: Dr. Patrick Dongosolo Kamalo – Consultant ...

African Journals Online (AJOL)

Dr. Yohane Gadama (YG), an MMJ intern, interviews Dr. Patrick Dongosolo Kamalo (PDK) on his work as Malawi's only local practicing neurosurgeon, the launch of Blantyre Institute of Neurological Sciences (BINS) and the beginning of Neurosurgery training in Malawi ...

Mishra, Dr A C

Indian Academy of Sciences (India)

Elected: 2009 Section: Medicine. Mishra, Dr A C . Ph.D. (Pune), FNA. Date of birth: 1 July 1950. Specialization: Human Viral Infection & Zoonotic Diseases, Public Health Address: Director, Interactive Research School of Health Affairs, Bharati Vidyapeeth University, ...

Thiagarajan, Dr Pazhamaneri Subramaniam

Indian Academy of Sciences (India)

Elected: 1995 Section: Mathematical Sciences. Thiagarajan, Dr Pazhamaneri Subramaniam Ph.D. (Rice), FNASc. Date of birth: 9 November 1948. Specialization: Distributed Probabilistic Systems, Hybrid Systems and Computational Systems Biology Address: Laboratory of System Pharmacology, Harvard Medical School, ...

Surveillance, Evaluation of Programmatic Management of Drug Resistant Tuberculosis (PMDT at DR-TB Centre, NITRD, New Delhi

Directory of Open Access Journals (Sweden)

Preeti Padda

2018-03-01

Full Text Available Background: PMDT was launched in 2007 in our country but drug resistant TB remains to be a public health problem. Effective surveillance is the backbone for success of any programme and true stands for PMDT. Aim & Objectives: To identify the strengths and constraints of the surveillance evaluation system. Material & Methods: A cross sectional study was conducted in January 2015 at DR-TB Centre of NITRD, New Delhi which caters to a population of 29 lacs. PMDT surveillance system was evaluated using attributes like simplicity, data quality, acceptability, positive predictive value, representativeness and timeliness defined by CDC, USA guidelines. Relevant information was collected using data abstraction form and interview with stakeholders. Data was analysed using EpiInfo 07 version. Results: Nodal officer and District TB officer are responsible for surveillance system activities of PMDT at DR-TB centre and district level, respectively. All the reports (100% were submitted on time and all the districts were reporting to DR-TB centre. 75% of TB-HIV coordinators found reporting formats to be simple but all the quarterly reports were found to be complete. Data quality was not found to be optimal. Conclusion: Private sector needs to be taken on board as they have no to minimal involvement in PMDT. For data quality improvement time to time training of medical officers and health workers should be organized.

Demand Response Technology Readiness Levels for Energy Management in Blocks of Buildings

Directory of Open Access Journals (Sweden)

Tracey Crosbie

2018-01-01

Full Text Available Fossil fuels deliver most of the flexibility in contemporary electricity systems. The pressing need to reduce CO2 emissions requires new methods to provide this flexibility. Demand response (DR offers consumers a significant role in the delivery of flexibility by reducing or shifting their electricity usage during periods of stress or constraint. Blocks of buildings offer more flexibility in the timing and use of energy than single buildings, however, and a lack of relevant scalable ICT tools hampers DR in blocks of buildings. To ameliorate this problem, a current innovation project called “Demand Response in Blocks of Buildings” (DR-BoB: www.dr-bob.eu has integrated existing technologies into a scalable cloud-based solution for DR in blocks of buildings. The degree to which the DR-BoB energy management solution can increase the ability of any given site to participate in DR is dependent upon its current energy systems, i.e., the energy metering, the telemetry and control technologies in building management systems, and the existence/capacity of local power generation and storage plants. To encourage the owners and managers of blocks of buildings to participate in DR, a method of assessing and validating the technological readiness to participate in DR energy management solutions at any given site is required. This paper describes the DR-BoB energy management solution and outlines what we have called the demand response technology readiness levels (DRTRLs for the implementation of such a solution in blocks of buildings.

Association between HLA-DR antigens and rheumatoid arthritis in Arabs.

OpenAIRE

Sattar, M A; al-Saffar, M; Guindi, R T; Sugathan, T N; Behbehani, K

1990-01-01

Eighty five Arab patients with classical and definite rheumatoid arthritis were typed to determine the prevalence of HLA A, B, C, and DR antigens. A significant increase in the prevalence of HLA-A10, B8, B21, and DR3 was found in comparison with a control population matched for age and sex. HLA-DR5 was significantly decreased in the patient group. The classical association of HLA-DR4 with rheumatoid arthritis could not be confirmed in the Arab patients resident in Kuwait, supporting reported ...

Two items: Transcription of a presentation by Dr. E. L. Albenesius, ''SRS burial ground operation from an historical perspective''; video tape entitled ''Burial ground operation''

International Nuclear Information System (INIS)

Holcomb, H.P.

1992-01-01

On February 6, 1992, approximately 35 SRS personnel from DOE, WSRC, and Dames and Moore attended a very informative talk given by Dr. E.L. Albenesius who discussed the operation of the SRS Burial Ground from an historical perspective. Dr. Albenesius, a Du Point retiree, formerly served as research manager of SRL's Environmental Effects and Solid Waste Management Technology Divisions among other assignments. One notable point Dr. Albenesius made was in answer to a question concerning what was the most important thing that could be done to reduce the hazard to man from buried waste. His response was to remove as much plutonium as practical prior to closure. In order to preserve this valuable information for the record, the program was audiotaped from which a point-by-point chronological transcription, with minor editing, was prepared

Budhani, Dr Ramesh Chandra

Indian Academy of Sciences (India)

Budhani, Dr Ramesh Chandra Ph.D. (IIT, Delhi), FNASc, FNA. Date of birth: 3 February 1955. Specialization: Renewable Energy, Nanoscale Systems, Experimental Condensed Matter Physics, Superconductivity and Magnetism Address: Department of Physics, Lasers & Photonics, Indian Institute of Technology, Kanpur 208 ...

Salunke, Dr Dinakar Mashnu

Indian Academy of Sciences (India)

Fellow Profile. Elected: 2001 Section: General Biology. Salunke, Dr Dinakar Mashnu Ph.D. (IISc), FNASc, FNA, FTWAS. Date of birth: 1 July 1955. Specialization: Structural Biology, Macromolecular Crystallography and Immunology Address: Director, International Centre for Genetic Engineering, & Biotechnology, Aruna Asaf ...

Watve, Dr Milind Gajanan

Indian Academy of Sciences (India)

Date of birth: 12 December 1957. Specialization: Wildlife Ecology & Animal Cognition, Evolutionary Biology, Computational Biology and Microbial Diversity Address: Professor, Biology, Indian Institute of Science Education & Research, Dr Homi Bhabha Road, Pashan, Pune 411 008, Maharashtra Contact: Office: (020) 2590 ...

Shivanna, Dr Kundaranahalli Ramalingaiah

Indian Academy of Sciences (India)

Elected: 1985 Section: Plant Sciences. Shivanna, Dr Kundaranahalli Ramalingaiah Ph.D. (Delhi), FNA, FNAAS, FNASc. Date of birth: 30 June 1940. Specialization: Pollen Biology, Reproductive Ecology and Conservation Biology Address: Odekar Farms, Nandihalli, via Thovinakere, Tumkur 572 138, Karnataka Contact:

Gaia DR1 documentation

Science.gov (United States)

van Leeuwen, F.; de Bruijne, J. H. J.; Arenou, F.; Comoretto, G.; Eyer, L.; Farras Casas, M.; Hambly, N.; Hobbs, D.; Salgado, J.; Utrilla Molina, E.; Vogt, S.; van Leeuwen, M.; Abreu, A.; Altmann, M.; Andrei, A.; Babusiaux, C.; Bastian, U.; Biermann, M.; Blanco-Cuaresma, S.; Bombrun, A.; Borrachero, R.; Brown, A. G. A.; Busonero, D.; Busso, G.; Butkevich, A.; Cantat-Gaudin, T.; Carrasco, J. M.; Castañeda, J.; Charnas, J.; Cheek, N.; Clementini, G.; Crowley, C.; Cuypers, J.; Davidson, M.; De Angeli, F.; De Ridder, J.; Evans, D.; Fabricius, C.; Findeisen, K.; Fleitas, J. M.; Gracia, G.; Guerra, R.; Guy, L.; Helmi, A.; Hernandez, J.; Holl, B.; Hutton, A.; Klioner, S.; Lammers, U.; Lecoeur-Taïbi, I.; Lindegren, L.; Luri, X.; Marinoni, S.; Marrese, P.; Messineo, R.; Michalik, D.; Mignard, F.; Montegriffo, P.; Mora, A.; Mowlavi, N.; Nienartowicz, K.; Pancino, E.; Panem, C.; Portell, J.; Rimoldini, L.; Riva, A.; Robin, A.; Siddiqui, H.; Smart, R.; Sordo, R.; Soria, S.; Turon, C.; Vallenari, A.; Voss, H.

2017-12-01

We present the first Gaia data release, Gaia DR1, consisting of astrometry and photometry for over 1 billion sources brighter than magnitude 20.7 in the white-light photometric band G of Gaia. The Gaia Data Processing and Analysis Consortium (DPAC) processed the raw measurements collected with the Gaia instruments during the first 14 months of the mission, and turned these into an astrometric and photometric catalogue. Gaia DR1 consists of three parts: an astrometric data set which contains the positions, parallaxes, and mean proper motions for about 2 million of the brightest stars in common with the Hipparcos and Tycho-2 catalogues (the primary astrometric data set) and the positions for an additional 1.1 billion sources (the secondary astrometric data set). The primary set forms the realisation of the Tycho-Gaia Astrometric Solution (TGAS). The second part of Gaia DR1 is the photometric data set, which contains the mean G-band magnitudes for all sources. The third part consists of the G-band light curves and the characteristics of 3000 Cepheid and RR Lyrae stars observed at high cadence around the south ecliptic pole. The positions and proper motions in the astrometric data set are given in a reference frame that is aligned with the International Celestial Reference Frame (ICRF) to better than 0.1 mas at epoch J2015.0, and non-rotating with respect to the ICRF to within 0.03 mas yr^-1. For the primary astrometric data set, the typical standard error for the positions and parallaxes is about 0.3 mas, while for the proper motions the typical standard error is about 1 mas yr^-1. Whereas it has been suggested in Gaia Collaboration et al. (2016a) that a systematic component of ∼0.3 mas should be 'added' (in quadrature) to the parallax uncertainties, Brown (2017) clarifies that reported parallax standard errors already include local systematics as a result of the calibration of the TGAS parallax uncertainties by comparison to Hipparcos parallaxes. For the subset of

Safety evaluation for packaging for 1720-DR sodium-filled tank

International Nuclear Information System (INIS)

Mercado, M.S.

1996-01-01

Preparations are under way to sell the sodium stored in the 1720-DR tank in the 1720-DR building. This will require that the tank, as well as the 1720-DR facility, be moved to the 300 Area, so that the sodium may be melted and transferred into a railroad tanker car. Because the sodium is a hazardous material and is being shipped in a nonspecification packaging, a safety evaluation for packaging (SEP) is required. This SEP approves the sodium-filled tank for a single shipment from the 105-DR area to the 300 Area

Chandrashekar, Dr Tavarekere Kalliah

Indian Academy of Sciences (India)

Fellow Profile. Elected: 2000 Section: Chemistry. Chandrashekar, Dr Tavarekere Kalliah Ph.D. (IISc), FNASc, FNA, FTWAS Council Service: 2013-15. Date of birth: 1 January 1956. Specialization: Bio-inorganic Chemistry, Synthetic Inorganic Chemistry and Catalysis Address: Senior Professor, School of Chemical Sciences, ...

Majumdar, Dr Subeer Suhash

Indian Academy of Sciences (India)

Fellow Profile. Elected: 2014 Section: Animal Sciences. Majumdar, Dr Subeer Suhash Ph.D. (nagpur), FNA, FNASc. Date of birth: 21 May 1961. Specialization: Animal Biotechnology, Transgenic Animals, Endocrinology Address: Director, National Institute of Animal Biotechnology, Gopan Pally, Hyderabad 500 046, A.P.

Gupta, Dr Chhitar Mal

Indian Academy of Sciences (India)

Gupta, Dr Chhitar Mal Ph.D. (Agra), FNA, FNASc, FAMS, FTWAS Council Service: 1998-2000. Date of birth: 1 September 1944. Specialization: Membrane Biology, Bio-organic Chemistry and Molecular Biophysics Address: Distinguished Professor and Infosys Chair, Institute of Bioinformatics & Applied Biotechnology, Room ...

Babu, Dr Cherukuri Raghavendra

Indian Academy of Sciences (India)

Fellow Profile. Elected: 1990 Section: Plant Sciences. Babu, Dr Cherukuri Raghavendra D.Phil. (Calcutta). Date of birth: 30 June 1940. Specialization: Biosystematics, Ecology and Population Genetics Address: Professor Emeritus, CEMDE, School of Environmental Studies, University of Delhi, Delhi 110 007, U.T.. Contact:

Anil, Dr Arga Chandrashekar

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 2015 Section: Earth & Planetary Sciences. Anil, Dr Arga Chandrashekar Ph.D. (Karnatak). Date of birth: 23 January 1959. Specialization: Biological Oceanography, Marine Ecology, Marine Biology Address: Chief Scientist, National Institute of Oceanography, Dona Paula 403 004, ...

Sharma, Dr Ram Swaroop

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1989 Section: Earth & Planetary Sciences. Sharma, Dr Ram Swaroop Ph.D. (Basel), FNA. Date of birth: 10 July 1937. Specialization: Metamorphic Petrology, Mineralogy and Precambrian Geology Address: 70/36, Pratapnagar, Sector 7, Sanganer (RHB), Jaipur 302 033, Rajasthan

Dr Satish R. Shetye

Indian Academy of Sciences (India)

Elected: 1992 Section: Earth & Planetary Sciences. Shetye, Dr Satish Ramnath Ph.D. (Washington), FNA, FNASc. Council Service: 1998-2003. Date of birth: 25 October 1950. Specialization: Physical Oceanography Address: Vice Chancellor, Goa University, Taleigao Plateau 403 206, Goa Contact: Office: (0832) 651 9001

Jena, Dr Prafulla Kumar

Indian Academy of Sciences (India)

Jena, Dr Prafulla Kumar Ph.D. (Utkal). Date of birth: 27 December 1931. Specialization: Extractive Metallurgy, Mineral Processing, Environmental Engineering and Materials Processing Address: Chairman, Institute of Advance Technology and Environmental Studies, 80A-831A Lewis Road, Bhubaneswar 751 002, Orissa

Kulkarni, Dr Mohan Gopalkrishna

Indian Academy of Sciences (India)

Elected: 1996 Section: Engineering & Technology. Kulkarni, Dr Mohan Gopalkrishna Ph.D. (Mumbai), FNAE. Date of birth: 14 November 1950. Specialization: Polymer Science & Engineering, Intellectual Property Address: Emeritus Scientist, Unit for R&D of Information Products, Tapovan, NCL Campus, Pashan Road, Pune ...

Apte, Dr Shree Kumar

Indian Academy of Sciences (India)

Elected: 2008 Section: General Biology. Apte, Dr Shree Kumar Ph.D. (Gujarat), FNA, FNASc, FNAAS. Date of birth: 18 October 1952. Specialization: Molecular Biology & Biotechnology, Physiology and Stress Biology of Bacteria & Plants Address: Emeritus Professor, Homi Bhabha National Institute, Anushakti Nagar, ...

Teaching medicine with the help of "Dr. House".

Science.gov (United States)

Jerrentrup, Andreas; Mueller, Tobias; Glowalla, Ulrich; Herder, Meike; Henrichs, Nadine; Neubauer, Andreas; Schaefer, Juergen R

2018-01-01

TV series such as "House MD", "Grey´s Anatomy" or "Emergency Room" are well perceived by medical students. Seminars featuring medical TV series such as "House MD" might serve as door-opener to attract medical students to learn more about rare diseases. The TV series "House MD" is troublesome for the main character Dr. House is an excellent diagnostician but at the same time a rather misanthropic person. Therefore, lecturing medicine with the help of "House MD" requires constant evaluation. From 2008 to 2016 we are using the well-known TV series "House MD" continuously to attract medical students and teach them about rare diseases as well as diagnostic strategies. We collected from 213 students a detailed questionnaire assessing their learning experience. 76.6% of our students (n = 157) reported to watching medical dramas on a regular basis. The Dr. House seminar was compared to traditional seminars and our students reported an improved learning effect (69.9%), better concentration (89.7%), higher motivation to participate (88.7%), and more fun (86.7%) (all pHouse's behavior quite critically. Likert assessment on a 5-point scale identified strong disagreement with Dr. House´s interpersonal skills in dealing with his colleagues (median = 1) and patients (median = 1). At the same time, the students strongly agreed with his outstanding diagnostic (median = 5) and therapeutic capabilities (median = 4). Medical students visiting a Dr. House teaching seminar are highly motivated to learn more about rare diseases. They were positively influenced by TV series such as Dr. House to improve their diagnostic and clinical skills. At the same time, they are critical enough not to see Dr. House as a role model for their own personality. Well performed medical TV shows such as Dr. House can successfully be used in an educational setting to motivate medical students to come into seminars to learn more about rare diseases.

GENESI-DR: Discovery, Access and on-Demand Processing in Federated Repositories

Science.gov (United States)

Cossu, Roberto; Pacini, Fabrizio; Parrini, Andrea; Santi, Eliana Li; Fusco, Luigi

2010-05-01

GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories) is a European Commission (EC)-funded project, kicked-off early 2008 lead by ESA; partners include Space Agencies (DLR, ASI, CNES), both space and no-space data providers such as ENEA (I), Infoterra (UK), K-SAT (N), NILU (N), JRC (EU) and industry as Elsag Datamat (I), CS (F) and TERRADUE (I). GENESI-DR intends to meet the challenge of facilitating "time to science" from different Earth Science disciplines in discovery, access and use (combining, integrating, processing, …) of historical and recent Earth-related data from space, airborne and in-situ sensors, which are archived in large distributed repositories. In fact, a common dedicated infrastructure such as the GENESI-DR one permits the Earth Science communities to derive objective information and to share knowledge in all environmental sensitive domains over a continuum of time and a variety of geographical scales so addressing urgent challenges such as Global Change. GENESI-DR federates data, information and knowledge for the management of our fragile planet in line with one of the major goals of the many international environmental programmes such as GMES, GEO/GEOSS. As of today, 12 different Digital Repositories hosting more than 60 heterogeneous dataset series are federated in GENESI-DR. Series include satellite data, in situ data, images acquired by airborne sensors, digital elevation models and model outputs. ESA has started providing access to: Category-1 data systematically available on Internet; level 3 data (e.g., GlobCover map, MERIS Global Vegetation Index); ASAR products available in ESA Virtual Archive and related to the Supersites initiatives. In all cases, existing data policies and security constraints are fully respected. GENESI-DR also gives access to Grid and Cloud computing resources allowing authorized users to run a number of different processing services on the available data. The GENESI-DR

Dr. Tulp's Anatomy Lesson by Rembrandt: the third day hypothesis.

Science.gov (United States)

Afek, Arnon; Friedman, Tal; Kugel, Chen; Barshack, Iris; Lurie, Doron J

2009-07-01

An autopsy was an important event in 17th century Holland. Autopsies were held in an 'anatomy theater' and performed according to a fixed protocol that often took up to 3 days to complete. Of the five group portraits painted by Rembrandt over the course of his career, two were anatomy lessons given by Dr. Tulp and Dr. Deyman. An examination of Rembrandt's painting Dr. Tulp's Anatomy Lesson (1632) and an X-ray image of the painting, as compared to other paintings of anatomy lessons from the same period, reveal interesting differences, such as positioning, and light and shadow. Not only was the autopsy not performed according to the usual protocol, but in this painting Rembrandt created a unique dramatic scene in his effort to tell a story. We suggest that Dr. Tulp and Rembrandt "modified" the painting of Dr. Tulp's anatomy lesson to emphasize Dr. Tulp's position as the greatest anatomist of his era--"Vesalius of Amsterdam," and as a way of demonstrating God's greatness by highlighting the hand as a symbol of the most glorious of God's creations.

Brahmayya Sastry, Dr Podila

Indian Academy of Sciences (India)

Elected: 1978 Section: Medicine. Brahmayya Sastry, Dr Podila Ph.D. (McGill). Date of birth: 24 May 1913. Date of death: 28 May 1993. Specialization: Physiology, Neurophysiology and Placental Physiology Last known address: Sitaramanilayam, Plot No. 9, Doctors Co-Operative Housing Colony, Waltair, Visakhapatnam ...

Chitnis, Dr Chetan Eknath

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 2009 Section: Medicine. Chitnis, Dr Chetan Eknath Ph.D. (UC, Berkeley), FNA. Date of birth: 3 April 1961. Specialization: Molecular Parasitology, Vaccine Development for Malaria and Molecular & Cell Biology Address: Head, Malaria Parasite Biology & Vaccine, Institut Pasteur, 28, ...

Sharma, Dr Surendra Kumar

Indian Academy of Sciences (India)

Elected: 2010 Section: Medicine. Sharma, Dr Surendra Kumar Ph.D. (AIIMS), MD (PGIMER, Chandigarh), FNASc, FNA. Date of birth: 22 February 1951. Specialization: Environmental Medicine, Infectious Diseases, Internal Medicine, Pulmonary & Critical Care and Sleep Medicine Address: B-5/3, B Block, Sector 13, RK ...

Valluri, Dr Sitaram Rao

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1971 Section: Engineering & Technology. Valluri, Dr Sitaram Rao Ph.D. (Caltech). Date of birth: 25 June 1924. Specialization: Metal Fatigue Address: 'Prashanthi', 659, 100 Feet Road, Indiranagar, Bengaluru 560 038, Karnataka Contact: Residence: (080) 2525 8294. YouTube ...

Shastry, Dr B Sriram

Indian Academy of Sciences (India)

Shastry, Dr B Sriram Ph.D. (Mumbai), FNA, FNASc, FTWAS. Date of birth: 26 November 1950. Specialization: Strongly-Correlated Fermi Systems, Quantum Integrable Systems Address: Distinguished Professor, Department of Physics, University of California, Santa Cruz, CA 95064, USA Contact: Office: (+1-831) 459 5849

Gangal, Dr Sharad Vishwanath

Indian Academy of Sciences (India)

Gangal, Dr Sharad Vishwanath Ph.D. (Mumbai), FNASc. Date of birth: 2 May 1937. Specialization: Allergy, Immunology and Biochemistry Address: Lakshmi Niwas, Opp. Santoshi Mata Temple (B Cabin), Sane Guruji Path, Naupada, Thane 400 602, Maharashtra Contact: Residence: (022) 2537 6961. Mobile: 93249 24307

Paranjpe, Dr Pramod Anand

Indian Academy of Sciences (India)

Elected: 1975 Section: Engineering & Technology. Paranjpe, Dr Pramod Anand D.Sc. Tech. (ETH Zurich). Date of birth: 1 April 1934. Specialization: Turbomachinery and Jet Propulsion Systems Address: 'Bahaar', 5, Hindustan Estate, Road No. 13, Kalyaninagar, Pune 411 006, Maharashtra Contact: Residence: (020) 2668 ...

Thakur, Dr Vikram Chandra

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1991 Section: Earth & Planetary Sciences. Thakur, Dr Vikram Chandra Ph.D. (London). Date of birth: 15 January 1940. Specialization: Structural Geology, Tectonics of Himalayan Geology and Active Tectonics Address: 9/12 (Lane 9), Ashirwad Eclave, Dehra Dun 248 001, ...

Gangal, Dr Sudha Gajanan

Indian Academy of Sciences (India)

Gangal, Dr Sudha Gajanan Ph.D. (Mumbai), FNA Council Service: 1995-97. Date of birth: 25 August 1934. Specialization: Cancer & Basic Immunology, Cell Biology and Genetic Diseases Address: 4, Mahavishnu Apartments, Dahanukar Colony A, Kothrud, Pune 411 029, Maharashtra Contact: Residence: (020) 2538 4382, ...

Mishra, Dr Rakesh K

Indian Academy of Sciences (India)

Mishra, Dr Rakesh K Ph.D. (Allahabad), FNASc, FNA. Date of birth: 14 April 1961. Specialization: Genomics, Chromatin, Epigenetics Address: Director, Centre for Cellular & Molecular Biology, Uppal Road, Hyderabad 500 007, A.P.. Contact: Office: (040) 2719 2600. Residence: (040) 2720 6400. Mobile: 94419 02188

Parnaik, Dr Veena Krishnaji

Indian Academy of Sciences (India)

Elected: 2008 Section: Animal Sciences. Parnaik, Dr Veena Krishnaji Ph.D. (Ohio State), FNA. Date of birth: 22 August 1953. Specialization: Cell Biology, Molecular Biology, Lamins and Nuclear Organisation Address: INSA Senior Scientist, Centre for Cellular & Molecular Biology, Uppal Road, Hyderabad 500 007, A.P.

Dr. Shi Hanzhang's Experience in Treating Andropathy

Institute of Scientific and Technical Information of China (English)

无

2007-01-01

@@ Dr. Shi Hanzhang (施汉章) of Dongzhimen Hospital affiliated to Beijing University of Traditional Chinese Medicine is experienced in both teaching and clinical practice, especially in treating andropathy, such as sexual disorder, infertility, and hyperplasia of the prostate. The author has the honour to follow him for study and really learned a lot from him. A brief introduction to Dr. Shi's way of thinking in treatment is as follows.

Volume celebrating the 60th birthday of Professor Dr. Franz Fie; Professor Dr. Franz Fiedler zum 60. Geburtstag

Energy Technology Data Exchange (ETDEWEB)

Beheng, K.D. [ed.

1998-01-01

This report was compiled in honor of Professor Dr. Franz Fiedler on the occasion of his 60th birthday on 7 January 1998. Its contributions deal with mesoscale modelling, the propagation of air pollutants, measurements of precipitation using radar, and prediction models. (orig./KW) [Deutsch] Dieser Bericht wurde aus Anlass des 60. Geburtstags von Herrn Prof. Dr. Franz Fiedler am 7. Januar 1998 zusammengestellt. Die Beitraege behandeln mesoskalige Modellierung, Ausbreitung von Luftschadstoffen, Niederschlagsmessung mit Radar und Vorhersagemodelle. (orig.)

For Dr. Nancy Snyderman's Parents, Staying Close to Family Is Key

Science.gov (United States)

... to move closer to their daughter and her family, as part of the next chapter in their lives. Photo courtesy of Dr. Nancy Snyderman As Chief Medical Editor for NBC News and host of the popular MSNBC show, Dr. Nancy , Dr. ...

DR and CR: Recent advances in technology

International Nuclear Information System (INIS)

Schaefer-Prokop, C.M.; De Boo, D.W.; Uffmann, M.; Prokop, M.

2009-01-01

After some initial reluctance, nowadays transition from conventional analogue-to-digital radiographic technique is realized in the vast majority of institutions. The eventual triumph of digital over conventional technique is related to its undoubted advantages with respect to image quality and improved image handling in the context of a picture archiving and communication system. CR represents the older system, which matured over decades and experienced some important recent improvements with respect to dose efficiency and work-flow efficiency that strengthened its position. It represents a very versatile, economically attractive system that is equally suited for integrated systems as well as for cassette-based imaging at the bedside. DR systems offer superb image quality and realistic options for dose reduction based on their high dose efficiency. While for a long time only integrated systems were on the market suited for a large patient throughput, also mobile DR systems became recently available. While for the next years, it is likely that DR and CR systems will coexist, the long term perspective of CR will depend on further innovations with respect to dose efficiency and signal-to-noise characteristics while for DR economical aspects and broader availability of mobile systems will play a role.

Bal, Dr Dattatreya Vaman

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1943 Section: Animal Sciences. Bal, Dr Dattatreya Vaman Ph.D. (Liverpool). Date of birth: 25 August 1905. Date of death: 1 April 1999. Specialization: Marine Zoology, Oceanography. Fisheries and Aquaculture Last known address: 104, Swaroop Complex, Karve Road, Pune 411 ...

Bhawalkar, Dr Dilip Devidas

Indian Academy of Sciences (India)

Fellow Profile. Elected: 1986 Section: Physics. Bhawalkar, Dr Dilip Devidas Ph.D. (Southampton), FNA, FNASc. Date of birth: 16 October 1940. Specialization: Lasers and laser Instrumentation Address: 26, Paramanu Nagar, Indore 452 013, M.P.. Contact: Office: (0731) 232 2707. Residence: (0731) 232 0031. Mobile: 93032 ...

Agrewala, Dr Javed Naim

Indian Academy of Sciences (India)

Agrewala, Dr Javed Naim Ph.D. (Agra), FNA, FNASc. Date of birth: 14 May 1961. Specialization: Immunology, Vaccine, Drug Discovery Address: Chief Scientist, Immunology Laboratory, Institute of Microbial Technology, Sector 39A, Chandigarh 160 036, U.T.. Contact: Office: (0172) 666 5261. Residence: (0172) 666 5514

Barua, Dr Asok Kumar

Indian Academy of Sciences (India)

Elected: 1987 Section: Physics. Barua, Dr Asok Kumar Ph.D. (Calcutta). Date of birth: 1 July 1936. Specialization: Solid State Materials, Thin Film Technology and Thin Film Solar Cells Address: Honorary Emeritus Professor, Indian Institute of Engineering Science & Technology, Shibpur, Howrah 711 103, W.B.. Contact:

Gurjar, Dr Mukund Keshao

Indian Academy of Sciences (India)

Gurjar, Dr Mukund Keshao Ph.D. (Nagpur and London), FNASc. Date of birth: 28 August 1952. Specialization: Carbohydrate Chemistry and Synthetic Organic Chemistry Address: Director, R&D, Emcure Pharmaceuticals Limited, P2, ITBT Park Phase II, Hinjwadi, Pune 411 057, Maharashtra Contact: Office: (020) 3982 1350, ...

Overall properties of the Gaia DR1 reference frame

Science.gov (United States)

Liu, N.; Zhu, Z.; Liu, J.-C.; Ding, C.-Y.

2017-03-01

Aims: The first Gaia data release (Gaia DR1) provides 2191 ICRF2 sources with their positions in the auxiliary quasar solution and five astrometric parameters - positions, parallaxes, and proper motions - for stars in common between the Tycho-2 catalogue and Gaia in the joint Tycho-Gaia astrometric solution (TGAS). We aim to analyze the overall properties of Gaia DR1 reference frame. Methods: We compare quasar positions of the auxiliary quasar solution with ICRF2 sources using different samples and evaluate the influence on the Gaia DR1 reference frame owing to the Galactic aberration effect over the J2000.0-J2015.0 period. Then we estimate the global rotation between TGAS with Tycho-2 proper motion systems to investigate the property of the Gaia DR1 reference frame. Finally, the Galactic kinematics analysis using the K-M giant proper motions is performed to understand the property of Gaia DR1 reference frame. Results: The positional comparison between the auxiliary quasar solution and ICRF2 shows negligible orientation and validates the declination bias of -0.1mas in Gaia quasar positions with respect to ICRF2. Galactic aberration effect is thought to cause an offset 0.01mas of the Z axis direction of Gaia DR1 reference frame. The global rotation between TGAS and Tycho-2 proper motion systems, obtained by different samples, shows a much smaller value than the claimed value 0.24mas yr-1. For the Galactic kinematics analysis of the TGAS K-M giants, we find possible non-zero Galactic rotation components beyond the classical Oort constants: the rigid part ωYG = -0.38±0.15mas yr-1 and the differential part ω^primeYG = -0.29±0.19mas yr-1 around the YG axis of Galactic coordinates, which indicates possible residual rotation in Gaia DR1 reference frame or problems in the current Galactic kinematical model. Conclusions: The Gaia DR1 reference frame is well aligned to ICRF2, and the possible influence of the Galactic aberration effect should be taken into consideration

Nageswara Rao, Dr Gullapalli

Indian Academy of Sciences (India)

Nageswara Rao, Dr Gullapalli M.D. (Opthal.) (AIIMS), FAMS, FACS, FRCS, FNASc. Date of birth: 1 September 1945. Specialization: Cornea, Community Eye Health and Eye Care Policy & Planning Address: Distinguished Chair of Eye Health, LV Prasad Eye Institute, LV Prasad Marg, Banjara Hills, Hyderabad 500 034, A.P.

Nandicoori, Dr Vinay Kumar

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 2018 Section: General Biology. Nandicoori, Dr Vinay Kumar Ph.D. (IISc), FNASc. Date of birth: 1 March 1969. Specialization: Molecular & Cellular Biology, Cell Signalling, Cell Biology Address: National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110 067, U.T.; Contact ...

Panda, Dr Subrat Kumar

Indian Academy of Sciences (India)

Panda, Dr Subrat Kumar M.B.B.S. (Utkal), M.D. (Path.) (AIIMS), FNA. Date of birth: 18 November 1954. Specialization: Liver Pathology, Viral Hepatitis and Molecular Biology/Virology Address: Professor, Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, U.T.. Contact:

Basu, Dr Sandip Kumar

Indian Academy of Sciences (India)

Fellow Profile. Elected: 1992 Section: General Biology. Basu, Dr Sandip Kumar Ph.D. (Calcutta), FNASc, FNA, FTWAS Council Service: 1995-97. Date of birth: 1 January 1944. Specialization: Cell Biology, Molecular Biology and Microbial Genetics Address: FD-426, Sector 3, Bidhan Nagar, Kolkata 700 106, W.B.. Contact:

[Dr. Atanasije Puljo: pioneer of Serbian dentistry].

Science.gov (United States)

Jovananović, Svetlana; Milovanović, Srdjan; Zagradjanin, Danica; Milovanović, Nebojša; Puzović, Dragana

2012-01-01

This paper describes the life and work of Dr. Atanasije Puljo (1878-1944). He was a volunteer in the Balkan wars, an active participant in the First World War; he was the first who noted the importance of team-work of a dentist and a surgeon in the care of jaw and facial injuries. He established primacy in this field, as he came up with this brilliant idea three years before other colleagues. His method of treatment of the upper jaw neglected fractures, called the Balkan method, was recognized worldwide. Dr. Puljo is the pioneer of dental radiology in Serbia, founder of the Odontology Clinic of the Medical Faculty and main supporter of the establishment of the School of Dentistry. Merits of Dr. Atanasije Puljo, medical practitioner with a broad knowledge in different fields, remain within the academic institution that was founded by this pioneer of dentistry in Serbia.

How Dr. Pierce Promoted Himself

Data.gov (United States)

Department of the Interior — This article is about Dr. Raymond V Pierce who owned St. Vincent Island before it became a refuge. The doctor painted advertisements for his famous “Woman’s Tonic”...

State Environmental Policy Act (SEPA) Checklist for the 105-DR Large Sodium Fire Facility Closure Plan

Energy Technology Data Exchange (ETDEWEB)

1990-09-01

The Hanford Site, located northwest of the city of Richland, Washington, houses reactors, chemical-separation systems, and related facilities used for the production of special nuclear materials, as well as for activities associated with nuclear energy development. The 105-DR Large Sodium Fire Facility (LSFF), which was in operation from about 1972 to 1986, was a research laboratory that occupied the former ventilation supply room on the southwest side of the 105-DR Reactor facility. The LSFF was established to provide means of investigating fire and safety aspects associated with large sodium or other metal alkali fires in the liquid metal fast breeder reactor (LMFBR) facilities. The 105-DR Reactor facility was designed and built in the 1950's and is located in the 100-D Area of the Hanford Site. The building housed the DR defense reactor, which was shut down in 1964. The LSFF is subject to the regulatory requirements for the storage and treatment of dangerous wastes. Clean closure is the proposed method of closure for the LSFF. Closure will be conducted pursuant to the requirements of the Washington Administrative Code (WAC) 173-303-610 (Ecology 1989). This closure plan presents a description of the facility, the history of wastes managed, and the procedures that will be followed to close the LSFF as an Alkali Metal Treatment Facility. No future use of the LSFF is expected.

Early onset of diabetes in the proband is the major determinant of risk in HLA DR3-DQ2/DR4-DQ8 siblings.

Science.gov (United States)

Gillespie, Kathleen M; Aitken, Rachel J; Wilson, Isabel; Williams, Alistair J K; Bingley, Polly J

2014-03-01

Islet autoimmunity is initiated in infancy, and primary prevention trials require children at high genetic risk to be identified before autoantibodies appear. To inform screening strategies, we evaluated risks of autoimmunity and diabetes associated with HLA DR3-DQ2/DR4-DQ8 in U.K. families. Extended HLA haplotypes were determined in 2,134 siblings from the Bart's-Oxford Study followed to a median age of 22 years. Risks of diabetes and islet autoimmunity (more than two antibodies) were estimated by survival analysis. Of 138 informative DR3-DQ2/DR4-DQ8 siblings, 63% shared both haplotypes with their diabetic proband, 29% shared one, and 8% shared neither. In HLA-identical DR3-DQ2/DR4-DQ8 siblings, the cumulative risk of diabetes by age 15 was 17% (vs. 6% in those sharing one haplotype or none; P = 0.095). Risk varied, however, with the age at the onset of diabetes in the proband; the cumulative risk of autoimmunity and/or diabetes by age 15 was 61% in siblings of probands diagnosed when younger than 10 years old compared with only 4.7% in those diagnosed after age 10 years (P sibling risk. This suggests that non-HLA genes or epigenetic/environmental factors that accelerate the progression of type 1 diabetes in the proband strongly affect risk in siblings.

Should pediatric patients wait for HLA-DR-matched renal transplants?

Science.gov (United States)

Gritsch, H A; Veale, J L; Leichtman, A B; Guidinger, M K; Magee, J C; McDonald, R A; Harmon, W E; Delmonico, F L; Ettenger, R B; Cecka, J M

2008-10-01

Graft survival rates from deceased donors aged 35 years or less among all primary pediatric kidney transplant recipients in the United States between 1996 and 2004 were retrospectively examined to determine the effect of HLA-DR mismatches on graft survival. Zero HLA-DR-mismatched kidneys had statistically comparable 5-year graft survival (71%), to 1-DR-mismatched kidneys (69%) and 2-DR-mismatched kidneys (71%). When compared to donors less than 35 years of age, the relative rate of allograft failure was 1.32 (p = 0.0326) for donor age greater than or equal to age 35. There was no statistical increase in the odds of developing a panel-reactive antibody (PRA) greater than 30% at the time of second waitlisting, based upon the degree of HLA-A, -B or -DR mismatch of the first transplant, nor was there a 'dose effect' when more HLA antigens were mismatched between the donor and recipient. Therefore, pediatric transplant programs should utilize the recently implemented Organ Procurement and Transplantation Network's (OPTN)allocation policy, which prioritizes pediatric recipients to receive kidneys from deceased donors less than 35 years of age, and should not turn down such kidney offers to wait for a better HLA-DR-matched kidney.

EVALUASI MANAJEMEN PENYIMPANAN OBAT DI GUDANG OBAT INSTALASI FARMASI RUMAH SAKIT UMUM DAERAH dr. R. SOEDJONO SELONG LOMBOK TIMUR

Directory of Open Access Journals (Sweden)

Nurul Qiyaam

2016-03-01

Full Text Available The storage management of drugs in hospitals must be good and true that the availability of pharmaceuticals is guaranteed in accordance with the needs of the hospital. This study aims to determine whether the drug storage in warehouses medicine is good and right and knowing how storage management of drugs in pharmaceutical warehouse Pharmacy Installation District General Hospital dr. R. Soedjono Selong. This is description research. Data collection using observational methods tailored to the interview with the standard parameter storage management medicine is good and right. The results showed that storage of medicines in pharmaceutical warehouse Pharmacy Installation District General Hospital dr.R.Soedjono Selong already well and truly based on five indicators of drug management at the stage of distribution, namely: the accuracy of data on the number of drugs on the card stock, the system arrangement of the warehouse, the percentage the value of the drug expired or damaged, the percentage of stock die and availability of drugs, as well as standards-based storage value of drugs that have three categories: category management stock classified as "good" with a value of 14, the category stock control classified as "good" with a value of 16 and category storage conditions classified as "good" with a value of 16.

Dr. David Sawyer, Mickey Mouse and Dr. David Brown attend a ceremony at Ronald McNair Middle School

Science.gov (United States)

1999-01-01

Dr. David Sawyer (left), Superintendent of the Brevard County School District, Mickey Mouse, and Dr. David Brown, a NASA astronaut, attend a tribute to NASA astronaut Ronald McNair held in the gymnasium of Ronald McNair Magnet School in Cocoa, Fla. During the tribute, Walt Disney World presented a portrait of McNair to the school, which had previously been renamed for the fallen astronaut. McNair was one of a crew of seven who lost their lives during an accident following launch of the Space Shuttle Challenger in January 1986.

Sirsat, Dr Satyavati Motiram

Indian Academy of Sciences (India)

Sirsat, Dr Satyavati Motiram Ph.D. (Mumbai). Date of birth: 7 October 1925. Date of death: 10 July 2010. Specialization: Medical Research (Cancer) & Ultrastructural Pathology and Hospice Care of the Dying Last known address: Bhagirathi Sadan, 17th Road, Khar, Mumbai 400 052. YouTube · Twitter · Facebook · Blog ...

David, Dr Joy Caesarina

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1982 Section: Medicine. David, Dr Joy Caesarina M.B.B.S., M.S. (Madras). Date of birth: 3 May 1927. Date of death: 20 April 2004. Specialization: Neuropharmacology Last known address: 292, 4th Main, 1st Block, Koramangala, Bengaluru 560 034. YouTube; Twitter; Facebook ...

Dr. Mostafa Moin, Minister of Science, Research and Technology, Islamic Republic of Iran

CERN Multimedia

Patrice Loïez

2001-01-01

L. to. r.:Dr Henrik Foeth, Team Leader, CMS experiment; Dr Daniel Denegri, Physics Coordinator, CMS experiment; Prof. Tejinder Virdee, Deputy Spokesman, CMS experiment; Prof. Luciano Maiani, CERN Director-General (signing); Mr Jean-Marie Dufour, Head of the Legal Service, Mr Ghodratollah Habibpour Gharakol (back); Dr Abdolali Sharghi, Advisor to the Minister and Director General, Office of International Scientific Cooperation, Ministry of Science, Research and Technology; Dr Mostafa Moin, Minister of Science, Research and Technology, Islamic Republic of Iran (signing); Dr Reza Mansouri, Director, International Scientific Meetings Office, Ministry of Science, Research and Technology; H. E. Dr Ali Khorram, Extraordinary and plenipotentiary Ambassador to the United Nations in Geneva and Dr Hans F. Hoffmann, CERN Director for Technology Transfer & for Scientific Computing. _

Abd-Allah, Dr. Adel-Gamil

African Journals Online (AJOL)

Abd-Allah, Dr. Adel-Gamil. Vol 12, No 4 (2000) - Articles CORRELATION BETWEEN UTERINE ARTERY FLOW VELOCITY WAVEFORMS AND ENDOMETRIAL HISTOPATHOLOGY IN WOMEN WITH PERIMENOPAUSAL AND POSTMENOPAUSAL BLEEDING. Details. ISSN: 1110-5607. AJOL African Journals Online.

NUMERICAL ALGORITHMS AT NON-ZERO CHEMICAL POTENTIAL. PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP, VOLUME 19

International Nuclear Information System (INIS)

Blum, T.; Creutz, M.

1999-01-01

The RIKEN BNL Research Center hosted its 19th workshop April 27th through May 1, 1999. The topic was Numerical Algorithms at Non-Zero Chemical Potential. QCD at a non-zero chemical potential (non-zero density) poses a long-standing unsolved challenge for lattice gauge theory. Indeed, it is the primary unresolved issue in the fundamental formulation of lattice gauge theory. The chemical potential renders conventional lattice actions complex, practically excluding the usual Monte Carlo techniques which rely on a positive definite measure for the partition function. This ''sign'' problem appears in a wide range of physical systems, ranging from strongly coupled electronic systems to QCD. The lack of a viable numerical technique at non-zero density is particularly acute since new exotic ''color superconducting'' phases of quark matter have recently been predicted in model calculations. A first principles confirmation of the phase diagram is desirable since experimental verification is not expected soon. At the workshop several proposals for new algorithms were made: cluster algorithms, direct simulation of Grassman variables, and a bosonization of the fermion determinant. All generated considerable discussion and seem worthy of continued investigation. Several interesting results using conventional algorithms were also presented: condensates in four fermion models, SU(2) gauge theory in fundamental and adjoint representations, and lessons learned from strong; coupling, non-zero temperature and heavy quarks applied to non-zero density simulations

Researcher Profile: An Interview With Dr. Rebecca J. Travnichek

Directory of Open Access Journals (Sweden)

Rebecca J. Travnichek

2011-04-01

Full Text Available

Dr. Rebecca Travnichek is a Family Financial Education Specialist with University of Missouri Extension. Dr. Travnichek currently serves as the Annual Conference Program Chair. She is also very active in the Association for Financial Counseling and Planning Education, where she serves on the Board of Directors. Dr. Travnichek has participated in leadership development programs at the state and national levels. She was involved in the initial proposal development of the Financial Security for All Community of Practice with eXtension and continues to be involved through several roles. She is active in the National Extension Association of Family and Consumer Sciences at the national and state levels, serving in multiple leadership roles. For the past three years, Dr. Travnichek has also served as the Editor of the Journal of the National Extension Association of Family and Consumer Sciences. She represents the type of person who makes the Financial Therapy Association a dynamic organization linking practitioners and academicians.

The research contributions of Dr. Paul Van Deusen

Science.gov (United States)

Thomas B. Lynch; Francis A. Roesch; John Paul McTague; Jeffrey H. Gove; Gregory A. Reams; Aaron R. Weiskittel

2015-01-01

Dr. Paul Van Deusen’s recent passing concluded a rich 30+-year research career dedicated to development and implementation of quantitative methods for forestry and natural resources. Since the early part of his career as a biometrician with the USDA Forest Service Southern Research Station in the 1980s-1990s and continuing with his later employment at NCASI, Dr. Van...

Kepler: A Search for Terrestrial Planets - SOC 9.3 DR25 Pipeline Parameter Configuration Reports

Science.gov (United States)

Campbell, Jennifer R.

2017-01-01

This document describes the manner in which the pipeline and algorithm parameters for the Kepler Science Operations Center (SOC) science data processing pipeline were managed. This document is intended for scientists and software developers who wish to better understand the software design for the final Kepler codebase (SOC 9.3) and the effect of the software parameters on the Data Release (DR) 25 archival products.

Treating Cataracts: Dr. Rachel Bishop's Top Tips for Your Eyes

Science.gov (United States)

... please turn JavaScript on. Feature: Treating Cataracts Dr. Rachel Bishop's Top Tips for Your Eyes Past Issues / ... exams, a healthy lifestyle, and eye protection. Dr. Rachel Bishop, chief of consult services at the National ...

Load management through agent based coordination of flexible electricity consumers

DEFF Research Database (Denmark)

Clausen, Anders; Demazeau, Yves; Jørgensen, Bo Nørregaard

2015-01-01

Demand Response (DR) offers a cost-effective and carbonfriendly way of performing load balancing. DR describes a change in the electricity consumption of flexible consumers in response to the supply situation. In DR, flexible consumers may perform their own load balancing through load management...

Remaining Sites Verification Package for 132-DR-1, 1608-DR Effluent Pumping Station. Attachment to Waste Site Reclassification Form 2005-035

International Nuclear Information System (INIS)

Carlson, R.A.

2005-01-01

Radiological characterization, decommissioning and demolition of the 132-DR-1 site, 1608-DR Effluent Pumping Station was performed in 1987. The current site conditions achieve the remedial action objectives and the corresponding remedial action goals established in the Remaining Sites ROD. Residual concentrations support future land uses that can be represented by a rural-residential scenario and pose no threat to groundwater or the Columbia River based on RESRAD modeling

Sproglige drømmerier

DEFF Research Database (Denmark)

Farø, Ken Joensen

2015-01-01

blev tidligere brugt i Danmarks Radio som pausesignal, afspillet på en spilledåse. Ak ja, det var dengang. Gå ind på nettet og lyt til den, hvis du ikke kender melodien. Det er national kulturarv. Mange bevingede ord indeholder en form af ”drøm(me)”, fx Martin Luther Kings ”I have a Dream”. Eller...

Murty, Dr Thutupalli Gopala Krishna

Indian Academy of Sciences (India)

Elected: 2002 Section: Engineering & Technology. Murty, Dr Thutupalli Gopala Krishna Ph.D. (Adelaide). Date of birth: 11 February 1944. Specialization: Optical Engineering, Thin Film Technology, Electro-Optical Instrumentation and Atmospheric Science Technologies Address: 848, 8th B Main, 17th Cross, ISRO Layout, ...

105-DR Large Sodium Fire Facility decontamination, sampling, and analysis plan

International Nuclear Information System (INIS)

Knaus, Z.C.

1995-01-01

This is the decontamination, sampling, and analysis plan for the closure activities at the 105-DR Large Sodium Fire Facility at Hanford Reservation. This document supports the 105-DR Large Sodium Fire Facility Closure Plan, DOE-RL-90-25. The 105-DR LSFF, which operated from about 1972 to 1986, was a research laboratory that occupied the former ventilation supply room on the southwest side of the 105-DR Reactor facility in the 100-D Area of the Hanford Site. The LSFF was established to investigate fire fighting and safety associated with alkali metal fires in the liquid metal fast breeder reactor facilities. The decontamination, sampling, and analysis plan identifies the decontamination procedures, sampling locations, any special handling requirements, quality control samples, required chemical analysis, and data validation needed to meet the requirements of the 105-DR Large Sodium Fire Facility Closure Plan in compliance with the Resource Conservation and Recovery Act

Analyize manifestations of DR and CT of 20 cases of bronchioloalveolar carcinoma

International Nuclear Information System (INIS)

Yang Zhongcheng

2006-01-01

Objective: Exploring the characters and changing rules between DR chest fluoroscopy and CT of bronchioloalveolar carcinoma. Methods: Collecting 20 cases DR chest fluoroscopies and CT scanning results of bron-chioloalveolar carcinoma, proved by biopsy, to reviewing analysis. Results: Bronchioloalveolar carcinoma divided into 3 types, nodular type, diffused type, infiltrated type. Nodular type focuses congregate and fused into node, density of the nodular shadow bad-distributed, vesical low-density shadow showed; Diffused type focus, multiple diffused nodish shadow gradually fused into patech consolidated shadow;Infiltrated focus distributed to pulmonary segment or lobes,like common pneumonia feature, existed airobronchogram, CT contrast scan shows typical 'CT angiogram'. Conclusion: No matter which type: nodular, diffused or infiltrated type, whose DR chest fluoroscopy and CT exists some features: Nodular type, DR chest fluoroscopy shows focuses mostly in periphery of pulmonary, margin with burr and plueral sunken sign, and whose HRCT manifestationshows typical small vesical sign in mediastinal window; Diffused type, DR chest fluoroscopy shows multiple diffused granular nodish shadow, however, CT manifestation can find more multiple focus than DR chest fluoroscopy, typical manifestation of HRCT is extensive small nodular shadow, with the thicken lobular interal; Infiltrated focus: DR chest fluoroscopy shows pulmonary consolidation and airobronchogram, And CT manifestations are CT angiogram and low-density consolidation shadow, wth specific property. Master all types of manifestation of DR and CT of bronchioloalveolar carcinoma, can help you improve the diagnosis of bronchioloalveolar carcinoma. (authors)

Managing diversity in organisations: practitioner and academic perspectives: report from a gender in management special interest group research event

OpenAIRE

Beauregard, T. Alexandra

2008-01-01

Purpose - This report aims to provide a brief summary of the presentations made by researchers and practitioners at the Gender in Management Special Interest Group’s research event, Managing Diversity in Organisations: Practitioner and Academic Perspectives.\\ud \\ud Design/methodology/approach - The research seminar was chaired by Dr. Adelina Broadbridge (University of Stirling) and Dr. Gillian Maxwell (Glasgow Caledonian University), and featured five presentations related to diversity in org...

Limited field investigation report for the 100-DR-1 Operable Unit

International Nuclear Information System (INIS)

1994-06-01

This limited field investigation (LFI) report summarizes the data collection and analysis activities conducted during the 100-DR-1 Source Operable Unite LFI and the associated qualitative risk assessment (QRA), and makes recommendations on the continued candidacy of high-priority sites for interim remedial measures (IRM). The results and recommendations presented in this report are generally independent of future land use scenarios. The 100-DR-1 Operable Unit is one of four operable units associated with the 100 D/DR Area at the Hanford Site. The 100-DR-1 Operable Unit encompasses approximately 1.5 km 2 (0.59 mi 2 ) and is located immediately adjacent to the Columbia River shoreline. In general, it contains waste facilities associated with the original plant facilities constructed to support D Reactor facilities, as well as cooling water retention basin systems for both D and DR Reactors. The 100-DR-1 LFI began the investigative phase of the remedial investigation for a select number of high-priority sites. The LFI was performed to provide additional data needed to support selection, design and implementation of IRM, if needed. The LFI included data compilation, nonintrusive investigations, intrusive investigations, summarization of 100 Area aggregate studies, and data evaluation

DR AVRAM JOZEF VINAVER (1862-1915) - PIONEER OF RADIOLOGY IN SERBIA.

Science.gov (United States)

Babić, Rade Radomir; Stanković Babić, Gordana

2015-01-01

Dr Abraham Joseph Vinaver (1862-1915), a Jew from Poland, was a pioneer of radiology in Serbia. He graduated from the Faculty of Medicine in Warsaw (1887), but lived and worked in abac (the Kingdom of Serbia) since 1890. Dr Abraham Joseph Vinarev - Career Development. He procured the first X-ray machine and developed radiological service in Sabac five years after the discovery of X-rays. These were the beginnings of radiology in Serbia. He introduced the application of artesian wells. Dr Abraham Joseph Vinarev - a Participant at the First Congress of Serbian Physicians and Naturalists, Belgrade 1904. "The diagnostic importance of X-rays in lung disease, especially in initial tuberculosis" and "Five Years of Treatment by X-Ray Machines" were the first works in the field of radiology in Serbia by this author. Dr Abraham Joseph Vinaver - Reserve Medical Officer in the Serbian Army. During the Balkan Wars, he was a volunteer with the rank of major engaged in military corps and he participated in the First World War as well. He died of malaria in 1915 in Gevgelija. "Dr Avram Vinaver"- Stanislav Vinarev. His dedication to work during the typhus epidemics was put into verses of a poem by his son Stanislav Vinarev. Dr Avram Vinaver Joseph was a noble man with a great heart, who selflessly sacrificed himself for the Serbian people and Serbia. He gave his contribution to the development of health services in Serbia, both in peacetime and wartime conditions. Dr Abraham Joseph Vinaver laid the foundations for today's radiology in Serbia.

Smart Distribution Boxes, Complete Energy Management

Energy Technology Data Exchange (ETDEWEB)

Platise, Uros

2010-09-15

Present households demand side management implementations are turning conventional appliances into smart ones to support auto demand (AutoDR) response function. Present concept features a direct link between the power meters and appliances. In this paper new concept and example of implementation of a so-called Smart Distribution Box (SmartDB) is represented for complete energy and power management. SmartDBs, as an intermediate layer, are extending smart grid power meter functionality to support AutoDR with fast and guaranteed response times, distributed power sources, and besides provide full control over energy management and extra safety functions to the consumers.

Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis

Science.gov (United States)

Lewis, Cathleen; Wright, Rebecca

2012-01-01

Dr. Cathleen Lewis was interviewed by Rebecca Wright during the presentation of an "Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis" on May 14, 2012. Topics included the care, size, and history of the spacesuit collection at the Smithsonian and the recent move to the state-of-the-art permanent storage facility at the Udvar-Hazy facility in Virginia.

The future of nursing: how important is discipline-specific knowledge? A conversation with Jacqueline Fawcett. Interview by Dr. Janie Butts and Dr. Karen Rich.

Science.gov (United States)

Fawcett, Jacqueline

2012-04-01

Nurses have long attempted to secure a unique identity for the profession. Many scholars are now promoting an interdisciplinary framework for nursing practice. Fawcett is convinced that interdisciplinary practice poses a danger for nursing to lose its identity and that interdisciplinary practice cannot be successful if members of each discipline do not understand the conceptual models, practice, and research of their own discipline. Dr. Janie Butts and Dr. Karen Rich interviewed Dr. Jacqueline Fawcett about her views related to discipline-specific knowledge and nursing's future. The authors conclude that Fawcett's scientific foundation gives nursing the solidarity and power necessary to determine the unique internal goods of its practice.

Data quality objectives summary report for the 100-BC-1, 100-BC-2, and 100-DR-1, and 100-DR-2 group 3 waste sites

International Nuclear Information System (INIS)

1997-03-01

The 100-BC-1, 100-BC-2, 100-DR-1, and 100-DR-2 Group 3 waste sites contain 22 past-practice liquid waste disposal sites and process effluent piping associated with four plutonium-production nuclear reactors that operated from 1944 to 1967. The 100-BC-1, 100-BC-2, 100-DR-1, and 100-DR-2 Group 3 waste sites are the third set of Hanford 100 Area sites to undergo remediation to the extent practicable. Like the sites listed in Groups 1 and 2, the Group 3 sites are considered high-priority because of the contaminants present and their proximity to the Columbia River. Remediation of the 100-BC-1, 100-HR-1 and 100-DR-1 radioactive liquid waste sites is planned to occur in two phases: The first phase, which has been completed, was a demonstration project in the 100-B/C Area to test field techniques and acquire contamination data. The second phase is full-scale remediation of all the reactor areas, starting in the 10-B/C Area, using the field experience gained in the first phase and each subsequent reactor area remediation. This document provides the DQO in support of remediation sampling and analysis at selected sites in the 100-B/C and 100-D Areas

DR. MIKA MAJALE MEMORIAL LECTURE

African Journals Online (AJOL)

He had four children Irene Majale,. Prof. Mike Majale (Architect) Victoria Majale Ojiambo and Chris Majale. Dr. Majale died on 21st April 1978. As an orthopaedic Surgeon he worked at Kenyatta. National Hospital (KNH), Kabete Orthopaedic Unit and. Armed Forces Memorial Hospital. He did not do any private practice.

Ali, Dr Moizuddin Abdul Salim

Indian Academy of Sciences (India)

... Section: Animal Sciences. Ali, Dr Moizuddin Abdul Salim D.Sc. (Andhra), D.Sc. (h.c.), FNA. Date of birth: 12 November 1896. Date of death: 20 June 1987. Specialization: Ecology, Zoogeography, Nature Conservation, Ornithology Last known address: No. 46, Pali Hill, Bombay 400 050. YouTube; Twitter; Facebook; Blog ...

APLIKASI TECHNOLOGY ACCEPTANCE MODEL PADA SISTEM INFORMASI MANAJEMEN RUMAH SAKIT DI RUMAH SAKIT ORTOPEDI PROF. DR. R. SOEHARSO SURAKARTA

OpenAIRE

Supriyanti Supriyanti; Muhammad Cholil

2017-01-01

The purpose of this study to apply the Technology Acceptance Model (TAM) on the Hospital Management Information System. This research is important because changes in hospital management information system (SIMRS) of the old system in collaboration with third parties to the new system is a standalone system that was developed by the IT team RSO Prof. dr. R. Soeharso requires a process of transition, which for some employees lead to conflict in the process of adaptation. This stu...

Separátory, sedimentační nádrže včetně funkce retenční nádrže Jeneweinova

OpenAIRE

Turic, Jakub

2016-01-01

Tato bakalářská práce se zabývá problematikou separátorů a sedimentačních nádrží, včetně funkce retenční nádrže Jeneweinova v Brně. Popisuje základní fyzikální a hydrodynamické vlastnosti vod a rozděluje její znečištění. Dále se zabývá popisem jednotlivých separačních a sedimentačních nádrží, jejich účel a využití. Zabývá se vznikem povodní a využití retenčních nádrží jako protipovodňové ochrany. Součástí práce je popis retenční nádrže Jeneweinova, její návrh, účel a funkce. The subject of...

Raghavarao, Dr Karumanchi Srisaila Mallikarjuna S

Indian Academy of Sciences (India)

Elected: 2014 Section: Engineering & Technology. Raghavarao, Dr Karumanchi Srisaila Mallikarjuna S Ph.D. (Mumbai), FNAE, FNAAS. Specialization: Food Engineering, Biotechnology Address: Chief Scientist, Department of Food Engineering, Central Food Technological Research Institute, Mysore 570 020, Karnataka

Dr. John Marburger visits DESY

CERN Multimedia

2003-01-01

Dr. John Marburger, Director of the United States Office of Science and Technology Policy, visited the research center DESY in Hamburg. The American physicist wanted to inform himself about the status of the TESLA X-ray laser and the TESLA linear collider as well as the international collaboration at DESY (1/2 page).

Den europæiske drøm - om EU

DEFF Research Database (Denmark)

Østergaard, Uffe

2007-01-01

Anmeldelse af: Jeremy Rifkin: Den europæiske drøm (Informations Forlag, 2006). Oversat fra engelsk efter: "The European Dream: How Europe's Vision of the Future Is Quietly Eclipsing the American Dream" (2004)......Anmeldelse af: Jeremy Rifkin: Den europæiske drøm (Informations Forlag, 2006). Oversat fra engelsk efter: "The European Dream: How Europe's Vision of the Future Is Quietly Eclipsing the American Dream" (2004)...

Dr. David Syz, State Secretary for Economic Affairs, Switzerland

CERN Multimedia

Maximilien Brice

2003-01-01

Dr. David Syz, State Secretary for Economic Affairs, Switzerland is seen here (seventh from right) visiting the assembly hall for the ATLAS experiment during his recent visit to CERN. To his right is Dr. Peter Jenni (blue shirt), spokesperson for the ATLAS Collaboration. The horizontal metal cylinder behind the group is one of the eight vacuum vessels for the superconducting coils of the ATLAS barrel toroid magnet system.

Celebrating the Life and Legacy of Dr. John Hope Franklin

Science.gov (United States)

Harris, Robert L., Jr.; Levering-Lewis, David; French, John D.; Wharton, Clifton R., Jr.

2009-01-01

Dr. John Hope Franklin chronicled the experiences of African-Americans like no one before him, forcing America to recognize Black history as American history. His contributions were innumerable and his impact was abiding. In celebration of his life and legacy, the authors profile the celebrated scholar and activist, Dr. John Hope Franklin.

Dr Jacob van der Land, marine biologist extraordinary

OpenAIRE

Bruggen, van, A.C.

2001-01-01

This contribution is an attempt to sketch the life and works of Dr Jacob van der Land, curator of worms and chief marine biologist of the National Museum of Natural History, on the occasion of his official retirement. Born in 1935, Jacob van der Land read biology at Leiden University (1958-1964), where he obtained his Ph.D. in 1970 on a treatise on the Priapulida under the supervision of Prof. Dr L.D. Brongersma. In 1964 he was appointed curator of worms in the museum. Later on he took over l...

Stemcell Information: SKIP000811 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available day No 5% ... RIKEN BioResouce Center (RIKEN ... BRC) 理化学研究所バイオリソースセンター RIKEN BioResouce Center (RIKEN ... BRC) 理化学...研究所バイオリソースセンター Available RIKEN BioResouce Center (RIKEN ... BRC) 理化学

Stemcell Information: SKIP000809 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available Negative ... RIKEN BioResouce Center (RIKEN ... BRC) 理化学研究所バイオリ...ソースセンター RIKEN BioResouce Center (RIKEN ... BRC) 理化学研究所バイオリソースセンター Available RIKEN BioResouce Center (RIKEN ... BRC) 理化学

Stemcell Information: SKIP000810 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available No 5% ... RIKEN BioResouce Center (RIKEN ... BRC) 理化学研究所バイオリソースセンター RIKEN BioResouce Center (RIKEN ... BRC) 理化学...研究所バイオリソースセンター Available RIKEN BioResouce Center (RIKEN ... BRC) 理化学

The Honorable Dr Adolfo Urso, Vice Minister for Foreign Trade, "Viceministro delle Attivita' Produttive, Italia"

CERN Multimedia

Patrice Loïez

2002-01-01

Photo 01: The Honorable Dr Adolfo Urso, Deputy Minister for Productive Activities, Italy, visiting SM18 with (from l to r): Dr Roberto Saban, Technical Coordination and Planning, LHC machine; Prof. Luciano Maiani, CERN Director-General; Dr Mario Gerbino, Director General of the Ministry and Prof. Lucio Rossi, LHC Main Magnet and Superconductors (MMS) Group Leader. Photo 02: Prof. Luciano Maiani, CERN Director-General and The Honorable Dr Adolfo Urso, Deputy Minister for Productive Activities, Italy, in front of one of the LHC superconducting magnet in SM18. Photo 03 :In front of one of the LHC superconducting magnets - from left to right Dr Roberto Saban, Technical Coordination and Planning, LHC machine; The Honorable Dr Adolfo Urso, Deputy Minister for Productive Activities, Italy and Prof. Luciano Maiani, CERN Director-General. Photo 04: In the SM18 hall (from l. to r.) Prof. Luciano Maiani, CERN Director-General, The Honorable Dr Adolfo Urso, Deputy Minister for Productive Activities, Italy and Dr Mario Ge...

An overview of the safety pharmacology career of Dr. C.R. Hassler.

Science.gov (United States)

Hawk, M A; Pugsley, M K; Vinci, T; Wallery, J; Hassler, C R; Hamlin, R L

2017-09-01

Each year the Safety Pharmacology Society (SPS) recognizes an investigator who has had a marked impact upon the discipline. The 2016 recipient of the SPS Distinguished Service Award (DSA) was Dr. Craig R. Hassler. Dr. Hassler is one of the founding members of the SPS and has been actively engaged in physiological research for over 46years. Dr. Hassler delivered a talk entitled "My 43Years at Battelle Memorial Institute" to meeting attendees. In this article an overview is provided of the illustrious career of Dr. Hassler along with an account of the numerous animal models that were developed at Battelle under his guidance over the years. Copyright © 2017 Elsevier Inc. All rights reserved.

Influence of HLA-D/DR antigen disparity in CTL generation in vitro

International Nuclear Information System (INIS)

Johnsen, H.E.; Madsen, M.; Mossin, J.; Kristensen, T.

1983-01-01

This report describes the influence of HLA-D/-DR antigen disparity upon the level of cytotoxicity in allogeneic in vitro cultures. Allogeneic cultures, between unrelated HLA-D/-DR full house donors, tested in CML gave three different levels of cytotoxicity, termed weak, intermediate and strong cytotoxicity. HLA-D/-DR compatibility predicts weak cytotoxicity and two HLA-B antigen incompatibility predicts strong cytotoxicity. On the contrary, HLA-A antigens have no major influence upon the strength of cytotoxicity. Accepting that the MLC/CML reaction is an in vitro parallel to the in vivo transplantation of allogeneic tissue, the observations are in accordance with the results of HLA-D/-DR matching for graft survival in human renal transplantation. (author)

Granice podmorskih prostora jadranskih država

Directory of Open Access Journals (Sweden)

Marina Vokić Žužul

2015-09-01

Full Text Available U ovome radu analiziraju se sve dosada utvrđene granice jadranskog podmorja kao i one koje tak valja utvrditi, posebice u svjetlu novih istraživanja njegovih prirodnih bogatstava. Uz Hrvatsku i Italiju, koje dijele najveći dio morskog dna i podzemlja u Jadranu, pravo na epikontinentski pojas imaju i Crna Gora te Albanija. Dvije jadranske države s kratkim obalama – Bosna i Hercegovina te Slovenija, države su u nepovoljnome geografskom položaju koje ne mogu imati epikontinentski pojas kao prirodni produžetak svoga kopnenog područja. Podmorski prostori tih država završavaju stoga na vanjskoj granici njihovih teritorijalnih mora. Osim razmatranja tih granica i sporazumno utvrđenih granica epikontinentskih pojaseva, autorice se kritički osvrću i na jednostrane akte Slovenije o proglašenju njezinoga epikontinentskog pojasa iz 2005. godine kao potpuno pravno neutemeljene akte. U središtu pozornosti ovoga rada je razmatranje granice koja dijeli podmorske prostore Hrvatske i Italije kao buduće granice dviju država i nad morskim dnom. Ta bi granična crta, u skladu s Konvencijom UN-a o pravu mora, trebala postati – jedinstvena morska granica njihovih epikontinentskih i gospodarskih pojaseva (odnosno ekološke zone Italije i zaštićenoga ekološko-ribolovnog pojasa Republike Hrvatske. Takva višefunkcionalna jedinstvena granična crta u najboljem je interesu pravne sigurnosti u svim načinima korištenja mora, a u međunarodnoj sudskoj i arbitražnoj praksi posljednjih desetljeća u potpunosti je zamijenila povlačenje različitih crta razgraničenja za više pojaseva u istome morskom prostoru. S obzirom na rezultate nedavno provedenih istraživanja potencijalnih nalazišta nafte i plina u južnom Jadranu, u radu se upozorava i na potrebu što skorijeg povlačenja crte bočnog razgraničenja epikontinentskih pojaseva Hrvatske i Crne Gore. Autorice analiziraju moguće pravce te nove granice, uzimajući u obzir znatno odstupanje od

Profile of Nasopharyngeal Carcinoma in Dr. Cipto Mangunkusumo National Hospital, 2010

Directory of Open Access Journals (Sweden)

Vito F. Jayalie

2017-01-01

Full Text Available Nasopharyngeal carcinoma (NPC is the most common head and neck malignancy in Indonesia. NPCpresents numerous challenges from non-specific signs and symptoms until lack of awareness from generalpractitioners (GP, which lead to late or missed diagnosis. Early diagnosis and prevention are proposedas the best solutions for this problem. In order to do that, we need a complete and well-managed patients’data. This study aims to reveal the demographic, clinical and histopathologic characteristics of NPC inIndonesia. A cross-sectional study was conducted by collecting medical records of all NPC patients in 2010from Otorhinolaryngology Department of Dr. Cipto Mangunkusumo National Hospital. The extracted datawere then analyzed to describe the problem of NPC in Indonesia. Out of 167 patients, 68.3% of the patientsare male and most of them are Sundanese and Javanese. Palpable lump in the neck is the most commoncomplaint in presentation (58.1%, followed by nasal congestion (49.1%. Salted fish consumption was themost prevalent risk factor (29.9%. Based on the histopathologic findings, 75.4% of the cases were classifiedas WHO-3 and around half of the patients (51% were in stage IV upon diagnosis. Studying demographic andclinical characteristics of NPC patients is the first step to overcome problems caused by NPC in Indonesia. Keywords: head and neck cancer, nasopharyngeal carcinoma, epidemiology  Profil Karsinoma Nasofaring di RSUPN Dr. Cipto Mangunkusumo, 2010 Abstrak Karsinoma nasofaring (KNF merupakan keganasan kepala leher yang paling sering di Indonesia.Tanda dan gejala KNF tidak spesifik dan dokter umum kurang waspada sehingga diagnosis terlambat ataugagal. Untuk mengatasi hal tersebut, diperlukan upaya pencegahan dan deteksi dini yang didasari profil KNF.Studi ini bertujuan untuk mengetahui gambaran demografi, gejala klinis dan karakteristik histopatologi pasienKNF di RSUPN Dr. Cipto Mangunkusumo. Penelitian menggunakan desain potong lintang dengan

Evaluasi Fungsi Insinerator Dalam Memusnahkan Limbah B3 Di Rumah Sakit NI Dr.Ramelan Surabaya

Directory of Open Access Journals (Sweden)

Jahn Leonard Saragih

2013-09-01

Full Text Available Pengelolaan limbah padat B3 di Rumah Sakit TNI Angkatan Laut Dr. Ramelan sangat penting diperhatikan karena dapat berdampak buruk apabila tidak dikelola dengan baik. Oleh sebab itu diperlukan adanya penelitian untuk mengidentifikasi jumlah timbulan dan penanganan limbah padat B3, mengevaluasi manajemen, penyimpanan sementara serta mengevaluasi proses insinerasi. Evaluasi fungsi incinerator di Rumah Sakit TNI Angkatan Laut Dr. Ramelan dilakukan dengan meneliti jumlah timbulan limbah B3, kapasitas pembakaran insinerator, suhu pembakaran insinerator, densitas limbah dan abu pembakaran, dan tes TCLP residu pembakaran incinerator Rumah Sakit TNI Angkatan Laut Dr. Ramelan. Dalam penelitian ini, Rumkital Dr. Ramelan memusnahkan limbah dengan incinerator. Limbah B3 yang dihasilkan Rumkital Dr. Ramelan dimusnakan dengan satu incinerator dengan type KAMINE TYPE BDR-INC 10. Limbah yang dimusnahkan di Rumkital Dr. Ramelan berasal dari Rumkital Dr. Ramelan dan Lantamal Perak. Setelah dilakukan penelitian langsung selama 14 hari berturut-turut, didapatkan bahwa rata-rata timbulan limbah B3 di Rumkital Dr. Ramelan adalah 89.98 Kg/hari dan dengan densitas rata-rata limbah ialah 166,67 kg/m3. Tinggat removal dari pembakaran limbah dengan incinerator di Rumah Sakit TNI Angkatan Laut Dr. Ramelan ialah 82,63%. Pengelolaan abu sisa incinerator Rumkital Dr. Ramelan belum sesuai dengan peraturan yang berlaku dan dari penelitian yang dilakukan yaitu pengujian kandungan abu incinerator, solidifikasi abu incinerator dengan perbandingan semen:abu adalah 1:3 dan uji TCLP, didapatkan bahwa limbah abu sisa insinerator Rumah Sakit TNI Angkatan Laut Dr. Ramelan Surabaya, dapat ditimbun pada landfill kategori I sesuai dengan Keputusan Kepala Bapedal No.4 Tahun 1995.

Stemcell Information: SKIP000808 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... RIKEN BioResouce Center (RIKEN ... BRC) 理化学研究所バイオリソースセンター RIKEN BioResouce Center (RIKEN ... BRC) 理化学...研究所バイオリソースセンター Available RIKEN BioResouce Center (RIKEN ... BRC) 理化学研究所バイオリソースセンター http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0136&type=1 ...

Decommissioning of DR 1, Final report

Energy Technology Data Exchange (ETDEWEB)

Lauridsen, Kurt

2006-01-15

The report describes the decommissioning activities carried out at the 2kW homogeneous reactor DR 1 at Risoe National Laboratory. The decommissioning work took place from summer 2004 until late autumn 2005. The components with the highest activity, the core vessel the recombiner and the piping and valves connected to these, were dismantled first by Danish Decommissioning's own technicians. Demolition of the control rod house and the biological shield as well as the removal of the floor in the reactor hall was carried out by an external demolition contractor. The building was emptied and left for other use. Clearance measurements of the building showed that radionuclide concentrations were everywhere below the clearance limit set by the Danish nuclear regulatory authorities. Furthermore, measurements on the surrounding area showed that there was no contamination that could be attributed to the operation and decommissioning of DR 1. (au)

Decommissioning of DR 1, Final report

International Nuclear Information System (INIS)

Lauridsen, Kurt

2006-01-01

The report describes the decommissioning activities carried out at the 2kW homogeneous reactor DR 1 at Risoe National Laboratory. The decommissioning work took place from summer 2004 until late autumn 2005. The components with the highest activity, the core vessel the recombiner and the piping and valves connected to these, were dismantled first by Danish Decommissioning's own technicians. Demolition of the control rod house and the biological shield as well as the removal of the floor in the reactor hall was carried out by an external demolition contractor. The building was emptied and left for other use. Clearance measurements of the building showed that radionuclide concentrations were everywhere below the clearance limit set by the Danish nuclear regulatory authorities. Furthermore, measurements on the surrounding area showed that there was no contamination that could be attributed to the operation and decommissioning of DR 1. (au)

MODEL KUANTITATIF MANAJEMEN STRES KERJA DAN MOTIVASI UNTUK MENINGKATKAN KINERJA PETUGAS REKAM MEDIS DI RS ORTOPEDI PROF. DR. R. SOEHARSO SURAKARTA

OpenAIRE

Laili Rahmatul Ilmi

2016-01-01

Background: Workload may indirectly cause stress. The ability to manage work stress may affect staff’s motivation and performance. The staff performance will affect decision-making in improving the service quality. Objective: This study aimed to analyze the relationship between stress management, work motivation and work performance. Method: This was an analytic observational study with a cross sectional approach. A sample of 19 medical record staff, working at Prof. Dr. R Soeharso ort...

Tun Dr. Mahathir’s Leadership Communication: The Confucian Perspective

Directory of Open Access Journals (Sweden)

Cheah Joyce Lynn-Sze

2017-01-01

Full Text Available Previous studies have provided valuable insights into the impact of culture on the concept of leadership communication. However, only a few studies that focused on exploring and understanding the values of Confucianism and its impact on the Chinese culture, especially in Malaysia. Thus, this study is among the first study to examine the leadership communication from the perspective of Confucianism towards the leadership of Dr. Mahathir from the perspective of the Chinese community in Malaysia. This study aims to assess the role of Confucian values in Dr. Mahathir’s leadership communication. This study interviewed 15 Chinese leaders. The findings reveal that three main Confucian values are relevant to Dr. Mahathir’s leadership communication. The Confucian values are Zhi (wisdom, Xin (trust and Xiao (filial piety. This study provides a new perspective on leadership communication from the context of cultural diversity in Malaysia which emphasizes on Confucian values.

DR2DI: a powerful computational tool for predicting novel drug-disease associations

Science.gov (United States)

Lu, Lu; Yu, Hua

2018-05-01

Finding the new related candidate diseases for known drugs provides an effective method for fast-speed and low-risk drug development. However, experimental identification of drug-disease associations is expensive and time-consuming. This motivates the need for developing in silico computational methods that can infer true drug-disease pairs with high confidence. In this study, we presented a novel and powerful computational tool, DR2DI, for accurately uncovering the potential associations between drugs and diseases using high-dimensional and heterogeneous omics data as information sources. Based on a unified and extended similarity kernel framework, DR2DI inferred the unknown relationships between drugs and diseases using Regularized Kernel Classifier. Importantly, DR2DI employed a semi-supervised and global learning algorithm which can be applied to uncover the diseases (drugs) associated with known and novel drugs (diseases). In silico global validation experiments showed that DR2DI significantly outperforms recent two approaches for predicting drug-disease associations. Detailed case studies further demonstrated that the therapeutic indications and side effects of drugs predicted by DR2DI could be validated by existing database records and literature, suggesting that DR2DI can be served as a useful bioinformatic tool for identifying the potential drug-disease associations and guiding drug repositioning. Our software and comparison codes are freely available at https://github.com/huayu1111/DR2DI.

DR2DI: a powerful computational tool for predicting novel drug-disease associations

Science.gov (United States)

Lu, Lu; Yu, Hua

2018-04-01

Finding the new related candidate diseases for known drugs provides an effective method for fast-speed and low-risk drug development. However, experimental identification of drug-disease associations is expensive and time-consuming. This motivates the need for developing in silico computational methods that can infer true drug-disease pairs with high confidence. In this study, we presented a novel and powerful computational tool, DR2DI, for accurately uncovering the potential associations between drugs and diseases using high-dimensional and heterogeneous omics data as information sources. Based on a unified and extended similarity kernel framework, DR2DI inferred the unknown relationships between drugs and diseases using Regularized Kernel Classifier. Importantly, DR2DI employed a semi-supervised and global learning algorithm which can be applied to uncover the diseases (drugs) associated with known and novel drugs (diseases). In silico global validation experiments showed that DR2DI significantly outperforms recent two approaches for predicting drug-disease associations. Detailed case studies further demonstrated that the therapeutic indications and side effects of drugs predicted by DR2DI could be validated by existing database records and literature, suggesting that DR2DI can be served as a useful bioinformatic tool for identifying the potential drug-disease associations and guiding drug repositioning. Our software and comparison codes are freely available at https://github.com/huayu1111/DR2DI.

Confessions of a Dr Math tutor

CSIR Research Space (South Africa)

Butgereit, L

2015-06-01

Full Text Available Mathematics look different on a small 3-inch screen of an inexpensive cell phone when compared to a 3-meter whiteboard in a mathematics classroom. Dr Math uses cell phone or mobile data "chat" technologies to assist primary and secondary school...

Stop words for “Dr Math”

CSIR Research Space (South Africa)

Butgereit, L

2011-05-01

Full Text Available “Dr Math” is a facility where primary and secondary school pupils can use MXit on their cell phones to get help with their mathematics homework. Pupils use an abbreviated “MXit lingo” leaving out most vowels and substituting various numerals...

Study on image quality and dosage comparison of F/S system and DR system

International Nuclear Information System (INIS)

Kim, Sun Chil; Jung, Jae Eun

2003-01-01

Currently, many hospital are hastening to introduce digital radiography systems. This is a direct result of the intentions to improve medical services and to digitalized radiology information systems, and is also leading to the improvement of medical imaging technology. Throughout F/S system's long history, many people have researched the image quality and dosage concerning these systems, and as a result, huge improvements in the dosage of patients were possible. Similarly, I believe that DR systems need the same kind of effort. Of course, decreases in dosage that ignore image quality are unthinkable. The results of experiments conducted by five hospitals during a period of 3 months brought to us the conclusions listed below. Based on the comparison and analysis of the exposure control of F/S systems and DR systems, DR systems generally showed higher exposure control for parts of the phantom that became thicker, and the exposure control improved rapidly as the thickness increased. DR systems still proved to be somewhat deficient in resolution measurements compared to existing F/S systems. The image processing part of DR systems contributed much to these result. Under conditions used clinically, the dosage measurements of DR systems were generally higher regardless of region. According to the evaluation of image quality, DR systems showed a higher degree of satisfaction as the thickness of the region became thinner. As mentioned above and based on the mutual relationship experiments between the dosage and image quality of F/S systems and DR systems, research to increase the satisfaction of DR systems must be considered

Association of leprosy with HLA-DR2 in a Southern Brazilian population

Directory of Open Access Journals (Sweden)

Visentainer J.E.L.

1997-01-01

Full Text Available The association between HLA specificities and leprosy was investigated in a Southern Brazilian population. One hundred and twenty-one patients and 147 controls were typed for HLA-A, B, Cw, DR and DQ. Patients were subdivided into the following subgroups, according to clinical, histological and immunological criteria: lepromatous (N = 55, tuberculoid (N = 32, dimorphous (N = 20, and indeterminate (N = 14. The frequencies of HLA specificities were compared between the total group of patients and controls, and between the same controls and each subgroup of patients. After correction of the probabilities, deviations were not significant, except for the DR2 specificity, which presented a frequency of 44.2% in the total group of patients and 56.3% in the subgroup of individuals with the tuberculoid form of the disease, compared to 23.3% in the controls. Stratified analysis showed that the increased DR2 frequency in the total group of patients was due to the subgroups with the tuberculoid and dimorphous forms. The relative risk of tuberculoid leprosy for DR2-positive individuals was 4.2, and the etiologic fraction of DR2 was 0.429. In conclusion, a positive association of the DR2 specificity with the tuberculoid form of leprosy, but not with the lepromatous, dimorphous, or indeterminate forms, was demonstrated in this Southern Brazilian population

Environmental management & audit 2: Management systems

OpenAIRE

2018-01-01

The present scientific monograph, entitled “Environmental management & audit“, is the result of three years’ work on an international project entitled “Environmental management in Russian companies – retraining courses for the sensibilization for and integration of Eco-Audit programs in corporate decision-making (RECOAUD)”. Within its more than 600 pages, the monograph features interesting texts written by 31 authors from the European Union and the Russian Federation, edited by dr. Borut Jere...

Portrait of Dr. Von Braun with Walt Disney, 1954.

Science.gov (United States)

1954-01-01

Marshall Center Director Dr. Wernher Von Braun is pictured with Walt Disney during a visit to the Marshall Space Flight Center in 1954. In the 1950s, Dr. Von Braun while working in California on the Saturn project, also worked with Disney studios as a technical director in making three films about Space Exploration for television. Disney's tour of Marshall in 1965 was Von Braun's hope for a renewed public interest in the future of the Space Program at NASA.

Stemcell Information: SKIP000806 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available change : every day No 5% Negative ... RIKEN BioResouce Center (RIKEN ... BRC) 理化学...研究所バイオリソースセンター RIKEN BioResouce Center (RIKEN ... BRC) 理化学研究所バイオリソースセンター Available RIKEN BioR...esouce Center (RIKEN ... BRC) 理化学研究所バイオリソースセンター http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0059&type=1 ...

Dr. Lindberg's Legacy : Charting A New Course | NIH MedlinePlus the Magazine

Science.gov (United States)

... more. Don also created the National Center for Biotechnology Information (NCBI). NCBI has been a focal point ... with Dr. Lindberg (right) and National Center for Biotechnology Information Director Dr. David Lipman (center) at a ...

Practitioner Profile: An Interview with Dr. Jerry Gale, LMFT

Directory of Open Access Journals (Sweden)

Jerry Gale

2012-06-01

Full Text Available Dr. Jerry Gale is an Associate Professor and the Clinical Director of the Marriage and Family Therapy Doctoral Program at the University of Georgia. He is a Licensed Marriage and Family Therapist and an approved supervisor of the American Association of Marriage and Family Therapists. He earned a B.A. from the University of Michigan, a MEd from the University of Arizona, and a Ph.D. from Texas Tech University. Over the course of his career, Dr. Gale has authored three books and over 60 articles and book chapters. He is a co-developer of a relational financial therapy approach that combines financial counseling with family therapy and has extensive training in clinical hypnosis, couples therapy, and family therapy, as well as mindfulness meditation. He is the recipient of the American Family Therapy Academy 2006 Outstanding Research Award. In addition to his work at the University of Georgia, Dr. Gale conducts therapy at Athens Associates for Counseling and Psychotherapy.

Management of polychlorinated biphenyls (PCBs) questions ampersand answers

International Nuclear Information System (INIS)

1995-11-01

This open-quotes Management of PCBs Questions and Answersclose quotes has been developed from a presentation given by Dr. John Smith of the Environmental Protection Agency (EPA), and the transcribed question and answer session which followed the presentation. Dr. Smith was featured at the first DOE complex-wide PCB Focus Group meeting held in San Francisco, California in December 1992. The meeting was attended by representatives from field elements who were actively involved in the management of PCBs. The meeting served as a forum for the exchange of information and discussion of PCB management issues. This document has been prepared as one of several guidance documents developed by the Department of Energy Office of Environmental Policy and Assistance (EH-41) (formerly the Office of Environmental Guidance, EH-23) to assist DOE elements in their PCB management programs. This document is organized into three parts: (1) an introduction describing the conception and development of this document, (2) a summary of Dr. Smith's presentation, and (3) the question and answer session

Comparative study between rib imaging of DR dual energy subtraction technology and chest imaging

International Nuclear Information System (INIS)

Yu Jianming; Lei Ziqiao; Kong Xiangchuang

2006-01-01

Objective: To investigate the application value of DR dual energy subtraction technology in rib lesions. Methods: 200 patients were performed with chest DR dual energy subtraction, comparing the rib imaging between DR of thorax and chest imaging using ROC analysis. Results: Among the total of 200 patients, there are 50 cases of rib calcification, 7 cases of rib destruction, 22 cases of rib fracture. The calcification, destruction and fracture were displayed respectively by ribs below diaphragm and rib markings. The analytic parameter of rib imaging of DR dual energy subtraction Az is 0.9367, while that of rib imaging of chest Az is 0.6830. Conclusion: DR dual energy subtraction technology is superior to chest imaging in the displaying of rib lesion and ribs below diaphragm. (authors)

Dr. Tulga Ersal at NSF Workshop Accessible Remote Testbeds ART'15

Science.gov (United States)

Event Archives Dr. Tulga Ersal at NSF Workshop Accessible Remote Testbeds ART'15 On November 12th, Dr Workshop on Accessible Remote Testbeds (ART'15) at Georgia Tech. From the event website: The rationale behind the ART'15 workshop is that remote-access testbeds could, if done right, significantly change how

Operating experiences on the co-generation system (CGS) as an uninterruptible power source (UPS) for the super-sized accelerator facility, RIBF of RIKEN

International Nuclear Information System (INIS)

Fujinawa, Tadashi; Yano, Yasushige

2011-01-01

The RI Beam Factory (RIBF) of RIKEN Nishina Center for Accelerator-Based Science, which succeeded in extracting first beam on December 28th 2006 as scheduled, is currently conducting nuclear physics experiments. The RIBF has six accelerators, one of which is the world's biggest and most powerful superconducting ring cyclotron (SRC). The accelerators require not only a huge amount of electricity but also a reliable power supply for the He-cryogenic system, vacuum system and superconducting magnet systems. For this purpose, the co-generation system (CGS) was introduced. A gas turbine generates 6.5 MW of power from liquid natural gas (LNG) and supplies it to the systems mentioned above as an uninterruptible power source (UPS). By utilizing gas heat exhaust from the gas turbine, the CGS will also supply cooled water to the cooling system of the RIBF accelerators as well as to the air-conditioning system for the bending. The CGS plant was completed on the 1st floor of the RIBF accelerator building and it began operating in April 2003. This paper covers the merits and demerits. (author)

Gaia: Mapping the Milky Way: The Scientific Promise of Gaia DR2

Science.gov (United States)

Walton, Nicholas; ESA Gaia, Data Processing and Analysis Consortium (DPAC)

2018-06-01

The ESA Gaia mission will release its first major all sky astrometric catalogue (Gaia DR2), of more than 1.3 billion stars in our Galaxy, on 25 April 2018.This presentation will provide an overview of the Gaia mission, focussing on the significant scientific potential of the Gaia DR2 release. This is based on 22 months of input data and allows for a full Gaia stand alone astrometric solution, including parallaxes and proper motions, of over 1.3 billion sources. The astrometric uncertainties in Gaia DR2 will be at the level of tens of micro-arcsec for sources Gproducts including the light curves of more than half a million variable stars, and the positions of more than thirteen thousand objects in our Solar System.Together with the Gaia DR2 data products and associated release documentation, a small number of performance verification papers, using Gaia DR2 data only to provide new insights into a number of key areas of Gaia science, will be published in a special edition of A&A. These will provide demonstrations of the scientific potential of the Gaia DR2 catalogue, and also highlight some of the issues and limitations involved in the use of the Gaia DR2 data.The Gaia mission and Gaia Data Releases are made possible through the dedication and expertise of the community scientists and engineers involved in the design, construction, and operation of Gaia (led by ESA) and the collaboration of some 450 scientists and software engineers responsible for the complex task of analysing the processed data (the DPAC). The role of both will be covered in the presentation.The presentation will conclude with a brief look ahead to the longer term Gaia data release schedule.

Analysis of Personal Hygiene and Food Handling on Patients Food Managementt in Rsup Dr. Mohammad Hoesin Palembang

OpenAIRE

Mirawati, Mirawati; Sitorus, Rico Januar; Hasyim, Hamzah

2011-01-01

Background : Hospital food hygiene and sanitation are generally less awake, which originated in the less hygienic food processing particularly related to personal hygiene of food handlers and poor food handling at every stage of implementation. This study aims to analyze the personal hygiene and food handling on Patients Food management in RSUP Dr. Mohammad Hoesin Palembang, 2010. Method : This study was descriptive using a qualitative approach. Sources of information in this study amounted...

Dr. Ding Hou 80 years young

NARCIS (Netherlands)

Baas, Pieter; Adema, Frits

2001-01-01

Eleven October 2001 is the 80th birthday of Dr. Ding Hou, much appreciated Honorary Staff Member of our Nationaal Herbarium Nederland. Time to reflect on the life and career of this modest but highly productive and talented botanist. Ding Hou was born in 1921 in Hsingkan, Kiangsi Province, China.

[Portrait of Dr Milenko Petrović (1884-1950)].

Science.gov (United States)

Kljaić, Leposava; Borota, Radoslav

2008-01-01

Dr Milenko Petrović was one of the very distinguished physicians in the history of Sombor city, who significantly contributed to the development of health care in Voivodina. His father Dimitrije was a professor in the High Teacher-training School in Sombor, recognized writer and politician of his epoch. He was born in Sombor in 1884, where he was educated and finished grammar school. For medical studies he moved to Budapest as a boarder of the famous Tekelianum, and graduated in 1908. He started specialisation in surgery, but being a great patriot he voluntarily recruited in the Serbian army to fight in Balkan liberation wars against Turkey. For his excellent work as a war surgeon he obtained many recognitions. After completing specialization in surgery in Debrecin, he returned to his native city Sombor, where he intended to practice as a physician, but because af the outbreak of the first world he was mobilized and sent to the front in Galicia. After the war he again returned to Sombor where he was immediatelly nominated for the main county physician and then begins his fruitful many year's work on the establishment and promotion of the health care in Sombor and broader territory. As the main county phsician he initiated the foundation and construction of the hospital in Sombor, because of high mortality rate among children, and spreading of contagious diseases like tuberculosis and trachoma. The construction of the hospital was completed in 1925 and Dr. Petrović was appointed its first director and this duty he performed for many years till the World War 2 in 1941. Under his management the hospital in Sombor became one of the best quality hospitals in the country and gave a big contribution to the promotion of health of the inhabitants of Voivodina. In spite of his extensive duties in the hospital. Dr. Milenko Petrović was very much engaged in social work, as the president of library "Laza Kosti ć". in the Soko association, Fire brigade, Rotary club, and he

Drømmefabrikken

Directory of Open Access Journals (Sweden)

Paulo Affonso Grisolli

1994-09-01

Full Text Available Som mangeårig producent af telenovelaer både i Brasilien og Portugal, kender Grisolli alle sider af telenovelaen: Novelaen som de fattiges drøm om rigdom og succes, novelaen som et redskab i TV-kanalernes kamp om seerne, som exportvare, som glansbillede under det brasillianske dik- tatur, som industriprodukt og som politisk igangsætter. I denne artikel be- skriver Grisolli sine erfaringer med gode og dårlige sider af telenovela- fascinationen i Latinamerika og præsenterer en ny genre, som er på vej frem i Brasilien, mini-serien. Artiklen er Grisollis foredrag på Folkekirkens Nødhjælps Konference om TV og Video i Latinamerika, november 1992.

The life and contribution of Dr. Ronald Gitelman: a pioneer of modern chiropractic science.

Science.gov (United States)

Vernon, Howard

2013-03-01

The life and contribution to chiropractic science of Dr. Ronald Gitelman is reviewed. Sources for this article included review of the notes prepared by Dr. Joseph Keating in his "biography" of the Canadian Memorial Chiropractic College (CMCC); review of the important articles published by Dr. Gitelman; review of the important projects undertaken by him along with various colleagues; notes from reminiscences obtained from many of these colleagues and discussions with his family. Dr. Gitelman's academic career spanned from 1963 to the late 1980's. During that time, he made foundational contributions to the development of chiropractic science including: developing the Archives (1974), the first collection of scientific articles supporting chiropractic science (which was subsequently published as the Chiropractic Archives Research Collection (CRAC)); delivering one of the few chiropractic papers at the seminal NINCDS conference (1975) and, developing the collaboration between CMCC and Dr. Kirkaldy-Willis at the University of Saskatoon (1976). He practiced in Toronto from 1961 to 2007. Dr. Gitelman was a pioneer in the development of chiropractic science. He died on October 7, 2012.

Allele Frequency - JSNP | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available nd 39 SNPs are assayed in three (POP_*) and two (RIKEN_japanese_*) panels, respectively. Derived from Flat f... assay (JBIC-allele and RIKEN_japanese_*), TaqMan assay (RIKEN-allele) or direct sequencing / allelic discri...unteers under informed consent RIKEN_japanese_normal_weight - 711 unrelated japanese normal weight volunteer...s ( body mass index RIKEN_japanese_obese - 796 unrelated japanese obese patients

Dr Michaels® product family (also branded as Soratinex®) versus Methylprednisolone aceponate - a comparative study of the effectiveness for the treatment of plaque psoriasis.

Science.gov (United States)

Hercogovấ, J; Fioranelli, M; Gianfaldoni, S; Chokoeva, A A; Tchernev, G; Wollina, U; Tirant, M; Novotny, F; Roccia, M G; Maximov, G K; França, K; Lotti, T

2016-01-01

As one of the most common dermatologic chronic-recurrent disease, variable therapeutic options are available today for management of psoriasis. Although topical high potency corticosteroids, alone or in association with salicylic acid or vitamin D analogues, are still considered the best treatment, they do not seem to possess the capability for a long-term control of the disease or prevent recurrences, as their side effects are major contraindications for continuative use. The aim of this study was to investigate whether Dr. Michaels® product family is comparable to methylprednisolone aceponate (MPA) as a viable alternative treatment option for the treatment and management of stable chronic plaque psoriasis. Thirty adults (13 male, 17 female, mean age 40 years) with mild to severe stable chronic plaque psoriasis, were included in the study. Patients were advised to treat the lesions of the two sides of their body (left and right) with two different unknown modalities for 8 weeks; the pack of Dr. Michaels® products on the left side (consisting of a cleansing gel, an ointment and a skin conditioner) and a placebo pack on the right side, consisting of a cleansing gel, methylprednisolone ointment and a placebo conditioner. Assessment was done using the Psoriasis Activity Severity Index (PASI) scores before treatment and after 2, 4, 6 and 8 weeks. The results achieved with the Dr. Michaels® (Soratinex®) product family for the treatment of chronic plaque psoriasis were better than the results achieved with methylprednisolone aceponate (MPA), even though quicker resolution was achieved with the steroid with 45% of patients achieving resolution within 8-10 days in comparison to 5-6 weeks in the Dr. Michaels® (Soratinex®) group. Before therapy, the mean PASI score of the LHS in Dr. Michaels® (Soratinex®) group was 13.8±4.1 SD and 14.2±4.2 SD in the RHS methylprednisolone aceponate (MPA) group. After 8 weeks of treatment 62% of the Dr. Michaels® (Soratinex

[Sexuality education on the Internet : From Dr. Sommer to Dr. Google].

Science.gov (United States)

Döring, Nicola

2017-09-01

Female and male adolescents in Germany are increasingly using the Internet to find information about sexuality and sexual health. This review paper summarizes what we know about the status quo of online sexuality education in Germany.Based on a systematic literature review including 40 papers from international, peer-reviewed journals spanning 2010-2017, this paper first describes different aspects of the sexuality-related online search behavior of adolescents: its prevalence, predictors, topics and contexts. One main finding is the fact that adolescents use a computer or smartphone to type their sexuality-related questions into the search engine Google or the search engine of the video platform YouTube.Based on 54 online searches, this paper subsequently presents the kind of sexuality-related online content adolescents find if they ask "Dr. Google" for sexual advice; a collection of 1236 authentic sexuality-related questions of adolescents was used for this analysis. It turned out that online sexuality education offered by leading professional organizations like the BZgA ("Bundeszentrale für gesundheitliche Aufklärung") or pro familia was nearly invisible, while numerous other providers of online sex education consistently appeared in the top Google search results. Among them were the "Dr. Sommer" team of the youth magazine Bravo; online healthcare and advice portals; online forums; the online encyclopedia Wikipedia and, above all, sex education channels on YouTube. In this paper, the latter are presented in more detail for the first time.The third part of the paper addresses the quality of online sexual education over four main areas of quality evaluation. The presentation of the status quo ends with some recommendations both for future research and for sexuality education in practice.

Words of gratitude to Dr. Michel Huguet

International Nuclear Information System (INIS)

Yoshikawa, Masaji

2003-01-01

It is impossible for the Japanese fusion community, in particular for those associated with the ITER Project,to hear about the retirement of Dr. Michel Huguet without a great amount of gratitude, recollections, warm feelings, and the inevitable sadness. He was a first-generation ITER EDA person. Three months after the signing of the ITER EDA Agreement in July 1992, he arrived at the Naka Joint Work Site as Deputy Director of the ITER Central Team and Head of the site and he stayed for more than ten years. The Naka site was for design and technical co-ordination in the areas of magnets, plasma control and heating, plant systems, buildings, etc. Dr. Huguet was considered a highly qualified person to fill the position, since he had been successful as Deputy Director in similar areas in the JET Joint Undertaking. During the ITER EDA he co-ordinated the R and D activities in areas for which the Naka Joint Work Site was responsible. These R and D results permitted the completion of the ITER design in the above areas under his supervision. We thank Dr. Huguet for his achievements and contributions to ITER. He played a crucial role in establishing the convincing scientific and technical basis for ITER implementation. This was only made possible by his broad abilities and his dedication to the cause of fusion in general and ITER in particular

HLA-DR-specific suppressor cells after repeated allogeneic sensitizations of human lymphocytes in vitro

International Nuclear Information System (INIS)

Sasportes, M.; Fradelizi, D.; Dausset, J.

1978-01-01

In conclusion, DR-specific suppressor cells can be induced by repeated in vitro sensitizations. They were able to decrease a secondary proliferation, to suppress consistently, in a primary proliferative assay, when added as third cells (primed twice against a DR antigen [PLT II] and γ-irradiated), the response of unprimed cells towards stimulating cells, which share a DR specificity with the priming cell of the PLT II. The suppression follows the D part of the recombinant haplotype within an HLA-B/D recombinant family and is specific for the DR antigen used twice as stimulator for production of the PLT II

Management coaching - et drømmeværktøj?

DEFF Research Database (Denmark)

Nielsen, Anne Ellerup; Nørreklit, Hanne

2004-01-01

ideologier ? ideer og tanker om hvordan social orden (gen)skabes ? er, der indlejret i disse management teorier og værktøjer? Mere præcist er formålet med denne artikel at undersøge hvorvidt de ideologiske antagelser om at (gen)skabe den sociale orden, som er indlejret i management coaching, som...

Dr. Francis Collins Is New NIH Director

Science.gov (United States)

... Ph.D., a physician and geneticist, is the new Director of the National Institutes of Health (NIH), part of the U.S. Department of Health and Human Services. President Barack Obama nominated Dr. Collins, who served as Director of ...

The 'Prof. Dr. Rómulo Lambre' Collection: an Argentinian sample of modern skeletons.

Science.gov (United States)

Salceda, S A; Desántolo, B; Mancuso, R García; Plischuk, M; Inda, A M

2012-08-01

This paper describes the 'Prof. Dr. Rómulo Lambre' skeletal collection. The Lambre Collection is housed in the School of Medical Sciences of the National University of La Plata and it consists of skeletal remains ceded by the Municipal Cemetery of La Plata. The collection has more than four hundred skeletons, with information on age, sex, nationality, date and cause of death. It was created for teaching and research purposes in compliance with current legislation, and its management meets guidelines specified in the Declaration of the Argentinian Association for Biological Anthropology on Research Ethics on Human Remains (2007). Copyright © 2012 Elsevier GmbH. All rights reserved.

Diabetes and Diabetic Retinopathy Management in East Africa: Knowledge, Attitudes, and Practices of Hospital Staff in Kenya.

Science.gov (United States)

Kupitz, David G; Fenwick, Eva; Kollmann, K H Martin; Holz, Frank G; Finger, Robert P

2014-01-01

Good diabetes mellitus (DM) and diabetic retinopathy (DR) management depends largely on involved medical staff, prompting us to investigate knowledge, attitudes, and practices about DM and DR at a tertiary referral center in Kenya. The design for this study is exploratory qualitative using semistructured interviews. Data from eye and diabetes clinic staff were collected until thematic saturation was reached, transcribed, and iteratively analyzed for relevant themes based on the constant comparative method. Among 46 participants (mean age, 38 years; 54% females), most were physicians (n = 25, 54%), followed by nurses (n = 14, 30%) and clinical officers (n = 6, 13%). Diabetes mellitus and DR were seen as urgent health problems (n = 42, 91%), and regular ophthalmic screening of diabetic patients was universally recommended. Two thirds (n = 32, 70%) were unaware of DM and DR management guidelines at the hospital. Participants identified training of staff in diagnosing (n = 30, 65%), efficient detection and referral of diabetic patients (n = 24, 52%), and improved outreach services (n = 14, 30%) as most pressing areas of need. Communication among hospital departments was found to be suboptimal. Reported barriers to good DR management were lack of retinal laser treatment and costs. Management outcomes for DM and DR may be improved by implementing integrated service provision, direct ophthalmological involvement in diabetic clinics, endorsement and effective distribution of guidelines, an increase in screening capacity, and the introduction of ongoing medical education covering DM and DR.

In Memoriam Dr. J. H. Kern

NARCIS (Netherlands)

Kalkman, C.

1974-01-01

On 29 July 1974 dr. J. H. Kern died at the age of 70. At the occasion of his official retirement from the Rijksherbarium staff (January 1969) Van Steenis and Van Ooststroom gave due recognition to his achievements in tropical botany and to his share in the progress of the knowledge of the Dutch

Identification and distribution of three serologically undetected alleles of HLA-DR by oligonucleotide x DNA typing analysis

International Nuclear Information System (INIS)

Tiercy, J.M.; Gorski, J.; Jeannet, M.; Mach, B.

1988-01-01

Recent progress in the molecular biology of human major histocompatibility complex class II genes (HLA-DP, -DQ, -DR) have shown that the genetic complexity and allelic polymorphism are greater than expected. In the case of HLA-DR, three DR β-chain loci have been identified and linked, two of which (DR βI and DR βIII, now assigned names HLA-DR1B and HLA-DR3B) are functional. The authors have shown that the HLA micropolymorphism detected at the DNA sequence level can easily be analyzed by hybridization with allele-specific oligonucleotides (HLA oligotyping). In the case of the HLA DRw52 supertypic specificity, which includes the DR3, DR5, DRw6, and DRw8 haplotypes, three alleles, referred to as DRw52a, DRw52b, and DRw52c, have recently been identified at the HLA-DR3B locus by DNA sequencing. Hybridization with locus- and allele-specific oligonucleotide probes (designated 52a, 52b, and 52c) has been performed on DNA from normal individuals forming a panel of 82 haplotypes to establish the distribution of these three alleles. Individuals of the DR3 haplotype had either the DRw52a or DRw52b allele, and individuals of extended haplotype HLA-A1,B8,DR3 had only the DRw52a allele. DR5 individuals all had the DRw52b allele, while individuals of DRw6 haplotype had the DRw52a, -52b, or -52c allele. None of these three alleles are found in DRw8 individuals. Analysis of this micropolymorphism, undetectable by common typing procedures, is therefore now operational for more accurate HLA matching for transplantation and for improving correlations between HLA and disease susceptibility

Intra HLA-D/DR region recombinant detected by primed lymphocyte typing (PLT)

DEFF Research Database (Denmark)

Jakobsen, B K; Kristensen, T; Lamm, L U

1983-01-01

lymphocyte typing (PLT) for HLA-D/DR region associated DP antigens. None of these studies gave evidence that the recombinations had occurred within the HLA region. Mixed leucocyte culture (MLC) tests within the families showed no detectable stimulation between the HLA identical siblings in two......The chromosome 6 markers, HLA-ABC, D, DR, MT, properdin factor Bf, and complement factors 2 (C2) and 5 (C4), were studied in three families, each of which included two HLA identical siblings, one or both of whom were known to be HLA-B: GLO recombinants. The families were also typed with primed...... to reactive reagents. One of these (GHx), reacted with a determinant which segregated within the GG family as if child G was a paternal recombinant between the HLA-D, DR, DP, and C4 loci, on the one hand, and on the other hand one or more loci governing other HLA-D/DR region controlled lymphocyte activating...

Visit of H.E. Dr Abdolrahim Gavahi, Secretary General, Economic Cooperation Organization, Islamic Republic of Iran

CERN Multimedia

Patrice Loïez

2001-01-01

Photo 01: L.to r. Prof. Galileo Violini, Head, UNESCO Office, Teheran; Mr Jan van der Boon, CERN Director of Administration; H.E. Dr Abdolrahim Gavahi, Secretary General, Economic Cooperation Organization, Islamic Republic of Iran (signing the Guest Book); Dr John Ellis, CERN Adviser for Non-Member State Relations and Dr Behzad Alipour Tehrany Photo 02: Mr Jan van der Boon, CERN Director of Administration (left) and Dr John Ellis, CERN Adviser for Non-Member State Relations (right) on the occasion of the visit of H.E. Dr Abdolrahim Gavahi, Secretary General, Economic Cooperation Organization, Islamic Republic of Iran.

Research in Hospitality Management: Contact

African Journals Online (AJOL)

Principal Contact. Dr Sjoerd A Gehrels Editor-in-Chief Stenden Hotel Management School, Academy of International Hospitality Research, Leeuwarden, The Netherlands Email: sjoerd.gehrels@stenden.com ...

Reminiscences by Dr. I.I. Rabi

International Nuclear Information System (INIS)

Rabi, I.I.

1973-01-01

Dr. I.I. Rabi, Professor of Physics, Columbia University, Nobel Laureate, adviser to presidents and an original member of the scientific advisory committees both of the United Nations and the IAEA, delivered the following address at the Salazar Atomic Centre, Mexico, in October 1972 he spoke on 'reminiscences from scientific advisory services to governments and international organizations'. (author)

Managing Productivity and Quality in the 1990s. Some Observations on TIMS (The Institute for Management Sciences) XXIX, 23-26 July 1989, Osaka, Japan

Science.gov (United States)

1989-10-01

often attempted. This profound knowledge must be possessed by management; hence Dr. Deming’s slogan: "Quality is Made in the Boardroom ." Dr. Deming...Out of the Crisis, MIT Center for Advanced Engineering Study, Cambridge, MA, 1982. 5. Lawrence M. Miller, Barbarians to Bureaucrats, Corporate Life

Agonistic Human Monoclonal Antibodies against Death Receptor 4 (DR4) | NCI Technology Transfer Center | TTC

Science.gov (United States)

The National Cancer Institute is seeking parties interested in licensing human monoclonal antibodies (mAbs) that bind to death receptor 4 ("DR4"). The tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and its functional receptors, DR4 and DR5, have been recognized as promising targets for cancer treatment.

Entity information life cycle for big data master data management and information integration

CERN Document Server

Talburt, John R

2015-01-01

Entity Information Life Cycle for Big Data walks you through the ins and outs of managing entity information so you can successfully achieve master data management (MDM) in the era of big data. This book explains big data's impact on MDM and the critical role of entity information management system (EIMS) in successful MDM. Expert authors Dr. John R. Talburt and Dr. Yinle Zhou provide a thorough background in the principles of managing the entity information life cycle and provide practical tips and techniques for implementing an EIMS, strategies for exploiting distributed processing to hand

White dwarf-main sequence binaries from LAMOST: the DR5 catalogue

Science.gov (United States)

Ren, J.-J.; Rebassa-Mansergas, A.; Parsons, S. G.; Liu, X.-W.; Luo, A.-L.; Kong, X.; Zhang, H.-T.

2018-03-01

We present the data release (DR) 5 catalogue of white dwarf-main sequence (WDMS) binaries from the Large Area Multi-Object fiber Spectroscopic Telescope (LAMOST). The catalogue contains 876 WDMS binaries, of which 757 are additions to our previous LAMOST DR1 sample and 357 are systems that have not been published before. We also describe a LAMOST-dedicated survey that aims at obtaining spectra of photometrically-selected WDMS binaries from the Sloan Digital Sky Survey (SDSS) that are expected to contain cool white dwarfs and/or early type M dwarf companions. This is a population under-represented in previous SDSS WDMS binary catalogues. We determine the stellar parameters (white dwarf effective temperatures, surface gravities and masses, and M dwarf spectral types) of the LAMOST DR5 WDMS binaries and make use of the parameter distributions to analyse the properties of the sample. We find that, despite our efforts, systems containing cool white dwarfs remain under-represented. Moreover, we make use of LAMOST DR5 and SDSS DR14 (when available) spectra to measure the Na I λλ 8183.27, 8194.81 absorption doublet and/or Hα emission radial velocities of our systems. This allows identifying 128 binaries displaying significant radial velocity variations, 76 of which are new. Finally, we cross-match our catalogue with the Catalina Surveys and identify 57 systems displaying light curve variations. These include 16 eclipsing systems, two of which are new, and nine binaries that are new eclipsing candidates. We calculate periodograms from the photometric data and measure (estimate) the orbital periods of 30 (15) WDMS binaries.

Dr.Zhang Ren's Experience in Acupuncture Treatment of Obstinate Eye Diseases

Institute of Scientific and Technical Information of China (English)

无

2006-01-01

@@ Dr.Zhang Ren (張仁), the board chairman of Shanghai Acupuncture Association, has been engaging in acupuncture treatment for more than 30years, during which he has kept on exploring the acupuncture therapies for obstinate diseases,especially for the obstinate eye diseases, ant summed up rich experience in this aspect. The following is a summary of what the author has learned from Dr. Zhang Ren.

[Dr Guillermo Contreras Da Silva, a relevant figure in the development of Chilean microbiology].

Science.gov (United States)

Cabello, Felipe C

2008-02-01

The influence of the work of Dr. Guillermo Contreras Da Silva and his colaborators on the evolution of microbiology in Chile is briefly analyzed. Dr. Contreras was trained in modern virology at Yale University with Dr. J. Melnick under the sponsorhip of the Rockefeller Foundation. During this training, he used serological methods to classify Cocksakie viruses. After his return to Chile, he studied the epidemiology of enteroviruses, including poliovirus. His laboratory, the country's first in modern virology, took an active role in Chile's first Sabin polio vaccination in 1961. Dr. Contreras and his group transformed the teaching and the character of microbiology in Chile from a descriptive medically oriented discipline into an autonomous, quantitative and experimental science. They modernized microbiology with the introduction of molecular biology and microbial genetics and fostered collaborations with allied biological sciences. Dr. Contreras was a Guggenheim Fellow, and until his retirement, was the Chief of the Viral Products Division, Bureau of Biologies, Ottawa, Canada.

His Excellency Professor Dr Che-Ho Wei, Chairman, National Science Council Executive Yuan, Republic of China

CERN Multimedia

Patrice Loïez

2002-01-01

Photo 01: Professor Dr. Che-Ho Wei signing the Guest Book with CERN Director-General, L. Maiani. Photo 02: Professor Dr. Che-Ho Wei. Photo 03::Professor Dr. Che-Ho Wei shaking hands with CERN Director-General, L. Maiani.

Practicing management and leadership: creating the information network for public health officials.

Science.gov (United States)

Baker, Edward L; Porter, Janet

2005-01-01

The Management Moment" is a regular column within the Journal of Public Health Management and Practice. Janet Porter, PhD, and Edward Baker, MD, MPH, MSc, are serving as The Management Moment Editors. Dr Porter is Associate Dean for Executive Education, The North Carolina Institute for Public Health, School of Public Health, at the University of North Carolina at Chapel Hill, and Dr Baker is Director of The North Carolina Institute for Public Health, School of Public Health, at the University of North Carolina at Chapel Hill. This column provides commentary and guidance on timely management issues commonly encountered in public health practice.

Characteristics of Rheumatoid Arthritis relative to HLA-DR in Saudi Arabia

International Nuclear Information System (INIS)

Al-Arfaj, Abdurhman S.

2001-01-01

The objective was to determine the clinical characteristics of rheumatoid arthritis in Saudi Arabia in relation to human leukocyte antigen type. A group of 91 rheumatoid arthritis patients, 72 females and 19 males were studied for the various clinical, laboratory and radiological parameters along with human leukocyte antigen-DR phenotypes. Since human leukocyte antigen-DR10 was most commonly associated with rheumatoid arthritis in our population, we compared those patients with human leukocyte antigen-DR10 to those without. The comparison yielded differences in the presence of rheumatoid nodules, erosions, corticosteroid treatment, and joint involvement at presentation, hemoglobin levels, and white cell count. Only the last 3 parameters showed a statistical significance. Human leukocyte antigen type of Saudi patients with rheumatoid arthritis influenced the course of the disease but only to a limited extent. (author)

Dr Oen Boen Ing Patriot doctor, social activist, and doctor of the poor

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Ravando Lie

2017-05-01

Full Text Available This article examines the efforts and achievements of Oen Boen Ing, a Tionghoa doctor, to improve the quality of health of the poorer inhabitants of Surakarta. Dr Oen played an important role in five different periods: Dutch colonialism, the Japanese occupation, the Indonesian revolution, Soekarno’s regime, and Suharto’s New Order. Known for being a benevolent doctor, activist, and patriot of the revolution during his life-time, Dr Oen also gave medical assistance to the needy, which famously earned him the accolade of “doctor of the poor”. During the Indonesian revolution, Dr Oen assisted the Student Soldiers (Tentara Pelajar and afterwards was appointed the member of Supreme Advisory Council (Dewan Pertimbangan Agung/DPA by Soekarno in 1949. As a benevolent doctor and activist, Dr Oen is remembered for founding the Panti Kosala Hospital which was renamed to perpetuate his name on 30 October 1983, exactly a year after his passing. When he died, thousands of peoples gathered to pay their final respects to the doctor. He was honoured with a ceremony conducted in the Mangkunegaran Palace. Dr Oen’s name will be eternally respected, especially in Surakarta.

Loss and benefit of DR system in mass screening for upper GI-tracts. Comparison with an II-TV based DR system and 100-mm roll-film system

International Nuclear Information System (INIS)

Ogura, Toshihiro; Fujita, Hiroshi.

1995-01-01

A 2048 x 2048 matrix II-TV based digital radiography (DR) system, a fully digital imaging system with diagnosis on the CRT monitor, had been introduced to Cancer Institute Hospital for the GI-tracts examinations since January 1990. Furthermore, we had applied it to the mass screening of upper GI-tract since November 1992. In the present study, a retrospective study on clinical evaluation and features of the DR system for the mass screening were investigated and compared with the screening data taken by conventional 100-mm roll-film technique in the previous year. The loss ratios and appearance of the mucosal patterns in upper gastric images were studied as well. Also determined was the reading time of those images in the mass screening situation. It was found that the loss ratio on the subject image information in 100-mm roll-film images was smaller than that in DR images. However, the DR images processed by windowing technique provided the perfect information without partially over or under density area. It was shown that the clinical image quality greatly depended on the radiographic technique by radiologists or technologists rather than on the imaging modality itself employed; even in II/TV-DR system, the radiographic technique is important. Because of some issues, including the size of CRT monitor, eyestrain for CRT monitor, and windowing operation regard to reading system, the reading time of CRT images was 1.44-2.05 times longer than that of 100-mm roll-film images. (author)

High Temperature Superconductors: From Delivery to Applications (Presentation from 2011 Ernest Orlando Lawrence Award-winner, Dr. Amit Goyal, and including introduction by Energy Secretary, Dr. Steven Chu)

International Nuclear Information System (INIS)

Goyal, Amit

2012-01-01

Dr. Amit Goyal, a high temperature superconductivity (HTS) researcher at Oak Ridge National Laboratory, was named a 2011 winner of the Department of Energy's Ernest Orlando Lawrence Award honoring U.S. scientists and engineers for exceptional contributions in research and development supporting DOE and its mission. Winner of the award in the inaugural category of Energy Science and Innovation, Dr. Goyal was cited for his work in 'pioneering research and transformative contributions to the field of applied high temperature superconductivity, including fundamental materials science advances and technical innovations enabling large-scale applications of these novel materials.' Following his basic research in grain-to-grain supercurrent transport, Dr. Goyal focused his energy in transitioning this fundamental understanding into cutting-edge technologies. Under OE sponsorship, Dr. Goyal co-invented the Rolling Assisted Bi-Axially Textured Substrate technology (RABiTS) that is used as a substrate for second generation HTS wires. OE support also led to the invention of Structural Single Crystal Faceted Fiber Substrate (SSIFFS) and the 3-D Self Assembly of Nanodot Columns. These inventions and associated R and D resulted in 7 R and D 100 Awards including the 2010 R and D Magazine's Innovator of the Year Award, 3 Federal Laboratory Consortium Excellence in Technology Transfer National Awards, a DOE Energy100 Award and many others. As a world authority on HTS materials, Dr. Goyal has presented OE-sponsored results in more than 150 invited talks, co-authored more than 350 papers and is a fellow of 7 professional societies.

Successful Collaborations with Dr. S. Raman in Research on Nuclear Data in Japan

International Nuclear Information System (INIS)

Mizumoto, Motoharu

2005-01-01

Since the early 1970s, Dr. Raman visited Japan many times and established a good and fruitful relationship with many scientists from universities and institutions in Japan. Many Japanese scientists, in particular young researchers, also worked together with him at Oak Ridge National Laboratory (ORNL). Through this successful collaboration, we made various achievements in the nuclear data and nuclear physics fields. Japanese researchers all remember Dr. Raman as a very active and warmhearted person. In this paper, some of the results that Dr. Raman established by collaborating with Japanese scientists will be presented

Dr. Andrew Foster: A Literature Review

Science.gov (United States)

Runnels, Joel

2017-01-01

Often compared to Laurent Clerc, Thomas Gallaudet, and Alexander Graham Bell, Dr. Andrew Foster was a deaf African American who founded 32 schools for the deaf in 13 African nations. The 60th anniversary of his arrival in Liberia and Ghana and the 30th anniversary of his tragic death in a Rwanda airplane accident both occur in 2017. Renewed…

Case-based Influence in Conflict Management

Science.gov (United States)

2014-10-31

AFRL-OSR-VA-TR-2014-0337 CASE-BASED INFLUENCE IN CONFLICT MANAGEMENT Robert Axelrod ARTIS RESEARCH & RISK MODELING Final Report 10/31/2014...FA9550-10-1-0373 Dr. Robert Axelrod - PI Dr. Richard Davis- PD ARTIS Research & Risk Modeling ARTIS 5741 Canyon Ridge North Cave Creek, AZ 85331-9318...analysis of the timing of cyber conflict that quickly received attention from over 30 countries. 3 1 Axelrod , Final Report and Publications Final

The Dr-nanos gene is essential for germ cell specification in the planarian Dugesia ryukyuensis.

Science.gov (United States)

Nakagawa, Haruka; Ishizu, Hirotsugu; Chinone, Ayako; Kobayashi, Kazuya; Matsumoto, Midori

2012-01-01

Homologs of nanos are required for the formation and maintenance of germline stem cell (GSC) systems and for gametogenesis in many metazoans. Planarians can change their reproductive mode seasonally, alternating between asexual and sexual reproduction; they develop and maintain their somatic stem cells (SSCs) and GCSs from pluripotent stem cells known as neoblasts. We isolated a nanos homolog, Dr-nanos, from the expressed sequence tags (ESTs) of the sexualized form of Dugesia ryukyuensis. We examined the expression of Dr-nanos in asexual and sexualized planarians by in situ hybridization and analyzed its function using RNA interference (RNAi) together with a planarian sexualization assay. A nanos homolog, Dr-nanos, was identified in the planarian D. ryukyuensis. Dr-nanos expression was observed in the ovarian primordial cells of the asexual worms. This expression increased in proportion to sexualization and was localized in the early germline cells of the ovaries and testes. In X-ray-irradiated worms, the expression of Dr-nanos decreased to a large extent, indicating that Dr-nanos is expressed in some subpopulations of stem cells, especially in GSCs. During the sexualization process, worms in which Dr-nanos was knocked down by RNAi exhibited decreased numbers of oogonia in the ovaries and failed to develop testes, whereas the somatic sexual organs were not affected. We conclude that Dr-nanos is essential for the development of germ cells in the ovaries and testes and may have a function in the early stages of germ cell specification, but not in the development of somatic sexual organs.

Dr. Ted Trimble: Why I Do Cancer Research

Science.gov (United States)

In a video, Dr. Ted Trimble talks about the importance of cancer research. World Cancer Research Day commemorates the important role research and cancer researchers play in reducing the global burden of cancer.

Chamber of Commerce reception for Dr. Lucas

Science.gov (United States)

1986-01-01

Dr. William R. Lucas, Marshall's fourth Center Director (1974-1986), delivers a speech in front of a picture of the lunar landscape with Earth looming in the background while attending a Huntsville Chamber of Commerce reception honoring his achievements as Director of Marshall Space Flight Center (MSFC).

Annotated Bibliography of Dr Salmani Nodoushan's Research on Education and Language Teaching

Science.gov (United States)

Etemadfar Kashani, Abbas Ali

2016-01-01

This is an annotated bibliography of the research conducted on education and language teaching and assessment by Dr. Mohammad Ali Salmani Nodoushan in the past 25 years. This bibliography is a precise picture of the current state of education and language teaching and assessment in Iran. Dr. Salmani Nodoushan is the most distinguished Iranian…

Human radiation studies: Remembering the early years. Oral history of Dr. Nadine Foreman, M.D., August 19, 1994

International Nuclear Information System (INIS)

1995-07-01

Dr. Nadine Foreman was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). Dr. Foreman was selected for interview because of the position she held at the University of California, San Francisco. Following a brief biographical sketch, Dr. Foreman describes her work with Dr. Mayo Soley using I-131 in treatment of hyperthyroidism, selection criteria for patients in the radioiodine project, work with Dr. Earl Miller, work at Highland Hospital, radioiodine treatment of diffuse toxic goiter (myxedema), the radiophosphorus and radioiodine programs with Dr. Bert Low-Beer, and treatment of polycythemia vera

Human radiation studies: Remembering the early years. Oral history of Dr. Nadine Foreman, M.D., August 19, 1994

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-07-01

Dr. Nadine Foreman was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). Dr. Foreman was selected for interview because of the position she held at the University of California, San Francisco. Following a brief biographical sketch, Dr. Foreman describes her work with Dr. Mayo Soley using I-131 in treatment of hyperthyroidism, selection criteria for patients in the radioiodine project, work with Dr. Earl Miller, work at Highland Hospital, radioiodine treatment of diffuse toxic goiter (myxedema), the radiophosphorus and radioiodine programs with Dr. Bert Low-Beer, and treatment of polycythemia vera.

HARD PARTON PHYSICS IN HIGH ENERGY NUCLEAR COLLISIONS. PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP, VOLUME 17

Energy Technology Data Exchange (ETDEWEB)

CARROLL,J.

1999-09-10

The RIKEN-BNL center workshop on ''Hard parton physics in high energy nuclear collisions'' was held at BNL from March 1st-5th! 1999. The focus of the workshop was on hard probes of nucleus-nucleus collisions that will be measured at RHIC with the PHENIX and STAR detectors. There were about 45 speakers and over 70 registered participants at the workshop, with roughly a quarter of the speakers from overseas. About 60% of the talks were theory talks. A nice overview of theory for RHIC was provided by George Sterman. The theoretical talks were on a wide range of topics in QCD which can be classified under the following: (a) energy loss and the Landau-Pomeranchuk-Migdal effect; (b) minijet production and equilibration; (c) small x physics and initial conditions; (d) nuclear parton distributions and shadowing; (e) spin physics; (f) photon, di-lepton, and charm production; and (g) hadronization, and simulations of high pt physics in event generators. Several of the experimental talks discussed the capabilities of the PHENIX and STAR detectors at RHIC in measuring high pt particles in heavy ion collisions. In general, these talks were included in the relevant theory sessions. A session was set aside to discuss the spin program at RHIC with polarized proton beams. In addition, there were speakers from 08, HERA, the fixed target experiments at Fermilab, and the CERN fixed target Pb+Pb program, who provided additional perspective on a range of issues of relevance to RHIC; from jets at the Tevatron, to saturation of parton distributions at HERA, and recent puzzling data on direct photon production in fixed target experiments, among others.

Doppler transcranien au cours de la drépanocytose chez l'enfant Malagasy

Science.gov (United States)

Herinirina, Nicolas Fanantenana; Rajaonarison, Lova Hasina Ny Ony Narindra; Herijoelison, Andry Roussel; Rakoto, Olivat Aimée Alson; Ahmad, Ahmad

2016-01-01

Introduction Le doppler transcrânien est un outil efficace permettant de dépister les enfants drépanocytaires à risque d'AVC. Méthodes Nous avons réalisé une étude descriptive transversale sur des enfants Malagasy âgés entre 24 mois et 15 ans (groupe 1: 57 drépanocytaires, groupe 2: 43 témoins) afin d’évaluer le profil vélocimétrique des artères cérébrales chez les drépanocytaires. Un examen Doppler transcrânien a été réalisé avec étude des flux sanguins cérébraux chez les enfants des deux groupes. Résultats Pour les sujets drépanocytaires, la vitesse moyenne (VM) de l'artère cérébrale moyenne était de 100,9 ± 26,8 cm/s, l'indice de pulsatilité (IP) de 0,73 ± 0,20, la différence entre les artères cérébrales moyennes droite et gauche (ACMr) de 19,8 ± 21,5 cm/s, le rapport des vitesses de l'artère cérébrale antérieure/artère cérébrale moyenne (ACA/ACM) de 0,7 ± 0,2. Pour les enfants non drépanocytaires, VM: 80,6 ± 19,3 cm/s, IP: 0,79 ± 0,14, ACMr: 17 ± 20,1 cm/s, ACA/ACM: 0,8 ± 0,2. La vélocité des enfants drépanocytaires était supérieure au groupe contrôle. Les vitesses ont été corrélées avec le taux d'hémoglobine et l’âge et non pas avec le sexe et le volume globulaire moyen. Conclusion Les vitesses circulatoires cérébrales sont élevées chez les drépanocytaires que les enfants non drépanocytaires et sont influencées par le taux d'hémoglobine et l’âge. PMID:27516829

Pengaruh Proses Pelapukan Clay Shale terhadap Perubahan Parameter Rasio Disintegritas (DR

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Idrus M Alatas

2017-04-01

Full Text Available The background of this research because of the frequent occurrence of the failure in the geotechnical design of clay shale caused by weathering. Disintegration ratio is a comparison of physical changes due to weathering at certain times of the initial conditions. Changes in physical properties due to clay shale weathering determined by the disintegration ratio (DR.Clay shale weathering will occur more quickly as a result of wetting and drying cycles when compared with the drying process. While due to the increased number of cycles of wetting at the same time, causing weathering on clay shale will be faster again. Until the 80th day of drying time, the magnitude DRof Semarang-Bawenclay shaleand Hambalang are the same, namely DR = 0.916 (completelly durable. However, due to wetting and drying cycles on day 32, samples of Semarang-Bawenclay shale is DR = 0.000 or non durable completelly, while on Hambalang clay shale in same day DR between 0.2117 to 0.3344. Generally Semarang-Bawen clay shale will be faster weathered than Hambalang clay shale. It is caused by the mineralogy content of Semarang-Bawen clay shale has dominated by Smectite, and Hambalangclay shalehas dominated mineral Kaolinite and Illlite.

Glaucoma: Eye-to-Eye with Dr. Rachel Bishop

Science.gov (United States)

... of this page please turn JavaScript on. Feature: Glaucoma Eye-to-Eye with Dr. Rachel Bishop Past ... nerves are pale and cupped—signs of advanced glaucoma. Yet the patient wasn't aware of any ...

Nitrogen availability in an apple orchard with weed management

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Gustavo Brunetto

2018-05-01

Full Text Available ABSTRACT: Weed management in apple orchards (Malus domestica can affect the leaching of nitrogen (N in soil. The study aimed to evaluate the potential leaching of N forms in soil of an apple orchard with different weed management treatments. The experiment was conducted in an apple orchard implanted in 2008. In October 2011, 80 plants were selected and the following treatments were implemented: no weed management (NM, desiccation of weeds on the tree row with herbicide use (DR and mechanical mowing of weeds on the tree row (MR. Yield was evaluated in the 2011/2012, 2012/2013 and 2013/2014 crop seasons. In May 2012 porous cup lysimeters were installed in the NM, DR and MR treatments. In the solution collected at 0.20m, NH4 +-N and NO3 --N were analyzed sixteen times and mineral N concentration was calculated. The highest concentrations of NO3 --N and mineral N occurred in soil solution with DR, which increases availability of the nutrient to apple trees, but also enhances the potential losses. Weed management and N flow in the solution did not affect apple yield.

Dr. William O. Coffee and his absorption cure for cataract.

Science.gov (United States)

Ferry, A P

1989-08-01

Dr. William O. Coffee was an ophthalmologist who conducted an office and mail-order practice in the Midwest from the 1880s until 1927. His main stock in trade was a self-discovered absorption cure for a variety of ocular diseases, with particular emphasis on the medical cure of cataracts. Dr. Coffee's career was a checkered one, marked by dubious credentials, exuberant self-promotion, unlikely and exaggerated claims of medical successes, plagiarism, and rejection by the medical "establishment." Certain parallels may be drawn between his activities and some currently observed practices in ophthalmology.

Generation of functional HLA-DR*1101 tetramers receptive for loading with pathogen or tumour derived synthetic peptides

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Protti Maria

2005-12-01

Full Text Available Abstract Background MHC class I-peptide tetramers are currently utilised to characterize CD8+ T cell responses at single cell level. The generation and use of MHC class II tetramers to study antigen-specific CD4+ T cells appears less straightforward. Most MHC class II tetramers are produced with a homogeneously built-in peptide, reducing greatly their flexibility of use. We attempted the generation of "empty" functional HLA-DR*1101 tetramers, receptive for loading with synthetic peptides by incubation. No such reagent is in fact available for this HLA-DR allele, one of the most frequent in the Caucasian population. Results We compared soluble MHC class II-immunoglobulin fusion proteins (HLA-DR*1101-Ig with soluble MHC class II protein fused with an optimised Bir site for enzymatic biotynilation (HLA-DR*1101-Bir, both produced in insect cells. The molecules were multimerised by binding fluorochrome-protein A or fluorochrome-streptavidin, respectively. We find that HLA-DR*1101-Bir molecules are superior to the HLA-DR*1101-Ig ones both in biochemical and functional terms. HLA-DR*1101-Bir molecules can be pulsed with at least three different promiscuous peptide epitopes, derived from Tetanus Toxoid, influenza HA and the tumour associated antigen MAGE-3 respectively, to stain specific CD4+ T cells. Both staining temperature and activation state of CD4+ T cells are critical for the binding of peptide-pulsed HLA-DR*1101-Bir to the cognate TCR. Conclusion It is therefore possible to generate a soluble recombinant HLA-DR*1101 backbone that is receptive for loading with different peptides to stain specific CD4+ T cells. As shown for other HLA-DR alleles, we confirm that not all the strategies to produce soluble HLA-DR*1101 multimers are equivalent.

[Homage to Professor Dr. Nicasio Etchepareborda].

Science.gov (United States)

1998-11-01

During a solemn academic act, de Main Classroom of the Facultad de Odontologia de Buenos Aires was named after Prof. Dr. Nicasio Etchepareborda. He has been the first professor at the Escuela de Odontologia and its organizer, after having obtained his Dentistry degree at the Dental School of Paris, in 1882. The new school was founded in 1891, and its activities began the following year.

Dr. PIAS: an integrative system for assessing the druggability of protein-protein interactions

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Furuya Toshio

2011-02-01

Full Text Available Abstract Background The amount of data on protein-protein interactions (PPIs available in public databases and in the literature has rapidly expanded in recent years. PPI data can provide useful information for researchers in pharmacology and medicine as well as those in interactome studies. There is urgent need for a novel methodology or software allowing the efficient utilization of PPI data in pharmacology and medicine. Results To address this need, we have developed the 'Druggable Protein-protein Interaction Assessment System' (Dr. PIAS. Dr. PIAS has a meta-database that stores various types of information (tertiary structures, drugs/chemicals, and biological functions associated with PPIs retrieved from public sources. By integrating this information, Dr. PIAS assesses whether a PPI is druggable as a target for small chemical ligands by using a supervised machine-learning method, support vector machine (SVM. Dr. PIAS holds not only known druggable PPIs but also all PPIs of human, mouse, rat, and human immunodeficiency virus (HIV proteins identified to date. Conclusions The design concept of Dr. PIAS is distinct from other published PPI databases in that it focuses on selecting the PPIs most likely to make good drug targets, rather than merely collecting PPI data.

Delivery room management of very low birth weight infants in Germany, Austria and Switzerland - a comparison of protocols

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Roehr CC

2010-11-01

Full Text Available Abstract Background Surveys from the USA, Australia and Spain have shown significant inter-institutional variation in delivery room (DR management of very low birth weight infants (VLBWI, Objective To investigate protocols for DR management of VLBWI in Germany, Austria and Switzerland and to compare these with the 2005 ILCOR guidelines. Methods DR management protocols were surveyed in a prospective, questionnaire-based survey in 2008. Results were compared between countries and between academic and non-academic units. Protocols were compared to the 2005 ILCOR guidelines. Results In total, 190/249 units (76% replied. Protocols for DR management existed in 94% of units. Statistically significant differences between countries were found regarding provision of 24 hr in house neonatal service; presence of a designated resuscitation area; devices for respiratory support; use of pressure-controlled manual ventilation devices; volume control by respirator; and dosage of Surfactant. There were no statistically significant differences regarding application and monitoring of supplementary oxygen, or targeted saturation levels, or for the use of sustained inflations. Comparison of academic and non-academic hospitals showed no significant differences, apart from the targeted saturation levels (SpO2 at 10 min. of life. Comparison with ILCOR guidelines showed good adherence to the 2005 recommendations. Summary Delivery room management in German, Austrian and Swiss neonatal units was commonly based on written protocols. Only minor differences were found regarding the DR setup, devices used and the targeted ranges for SpO2 and FiO2. DR management was in good accordance with 2005 ILCOR guidelines, some units already incorporated evidence beyond the ILCOR statement into their routine practice.

Typing for HLA-D/DR associated DP-antigens with the primed lymphocyte typing (PLT) technique

DEFF Research Database (Denmark)

Morling, N; Jakobsen, B K; Platz, P

1980-01-01

A total of 74 healthy unrelated random individuals and 36 patients with juvenile rheumatoid arthritis (JRA) were typed for HLA-D antigens with the homozygous typing cell technique and typed for HLA-D/DR associated DP-antigens with the primed lymphocyte typing (PLT) technique. All patients and some...... of the controls were also HLA-DR typed with a limited battery of anti-DR sera. Selected PLT-cells, specific for the HLA-D/DR antigens D/DRw1-8 and the local specificity D"H" were used. The results of the PLT-experiments were evaluated with the Normalized Median Response (NMR) method and the further procedure...

Engineering evaluation/cost analysis for the 105-DR and 105-F Reactor facilities and ancillary facilities

International Nuclear Information System (INIS)

Coenenberg, E.T.

1998-01-01

This document presents the results of an engineering evaluation/cost analysis (EE/CA) that was conducted to evaluate alternatives to address final disposition of the 105-DR and 105-F Reactor Buildings (subsequently referred to as facilities), including the fuel storage basins (FSB) and below-grade portions of the reactors, excluding the reactor blocks. The reactor blocks will remain in a safe storage mode for up to 75 years as identified in the Record the Decision (ROD) (58 FR 48509) for the Environmental Impact Statement (EIS), Decommissioning of Eight Surplus Production Reactors at the Hanford Site, Richland, Washington (DOE 1992a). This EE/CA also addresses final disposition of four ancillary facilities: 116-D and 116-DR Exhaust Air Stacks, 117-DR Exhaust Filter Building, and 119-DR Exhaust Air Sample Building. The 105-DR and 105-F facilities are located in the 100-D and 100-F Areas of the Hanford Site. In November 1989, the 100 Area of the Hanford Site was placed on the U.S. Environmental Protection Agency's (EPA) National Priorities List (NPL) under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). The 100 Area NPL includes the 100-D Area (which includes the 100-DR site) and the 100-F Area, which are in various stages of the remediation process. It has been determined by DOE that hazardous substances in the 105-DR, 105-F, and the four ancillary facilities may present a potential threat to human health or the environment, and that a non-time critical removal action at these facilities is warranted. To help determine the most appropriate action, DOE, in cooperation with the Washington State Department of Ecology (Ecology) and the EPA, has prepared this EE/CA. The scope of the evaluation includes the 105-DR and 105-F facilities and the four ancillary facilities. The 116-DR and 117-DR facilities are located within the boundaries of the 105-DR Large Sodium Fire Facility Treatment, Storage, and Disposal (TSD) unit, which is

Dr. Omalu Talks Childhood, Concussions, and CTE | Poster

Science.gov (United States)

Dr. Bennet Omalu, the famed forensic pathologist who discovered Chronic Traumatic Encephalopathy (CTE), recently spoke at NCI at Frederick about his upbringing as well as the trials he faced while working to educate the NFL about CTE.

HLA-DR typing by radioimmunoassay

International Nuclear Information System (INIS)

Tosi, R.; Tanigaki, N.; Centis, D.; Rossi, P.L.; Alfano, G.; Ferrara, G.B.; Pressman, D.

1980-01-01

A radioimmunoassay procedure is described by which peripheral blood lymphocytes can be typed for HLA-DR specificities. The major advantages of this method are the following: simple and reproducible procedure, no need for B lymphocyte separation, no need for optimal viability, and no need for preabsorption of antisera with platelets. This method will find an application in the genetic and biochemical analysis of the HLA complex, and in the clinical tests of Ia antigens for diagnostic or prognostic purposes and in retrospective transplant studies

[Perception of pain by patients receiving antiretroviral treatment in North Kivu, DR Congo].

Science.gov (United States)

Escoffier, Claire; Kambale, Alain; Paluku, Faustin; Kabuayi, Jean-Pierre; Boillot, François

2010-01-01

This operational research conducted among TB patients co-infected with HIV in North Kivu had three objectives: (i) to clarify the local perception of a certain type of pain (michi in the local language) in patients on antiretroviral treatment (ART); (ii) to identify the attitudes of health care personnel regarding the management of ART side effects; and (iii) to explore ways to improve the quality of life of patients on ART and provide them with pain relief. Twenty in-depth interviews were conducted with patients on ART and their medical care providers in district health centers of North-Kivu and at patients' homes. A semantic analysis of the term michi revealed a nosologic folk entity based on a naturalistic view of the body; the term michi is used to name: (i) the "roots" of plants or trees; (ii) channels (veins, arteries, but also nerves and tendons) in the body through which fluids (blood, water) and energy are conveyed; (iii) different types of acute pain, possibly located along these channels. The description (location, duration, and intensity) of the functional signs and the context of their occurrence (while taking Stavudine) confirmed the medical diagnosis of acute sensory neuropathies. Although a classic ART side effect, neuropathies are underdiagnosed by health workers who find it difficult to recognize signs of treatment toxicity in apparently trivial symptoms. Different reasons account for this: (i) healthcare staff have little time to spend with TB/HIV patients and thus provide inadequate management of functional symptoms; (ii) insufficient attention is paid to patients' acute pain, which is often perceived as "normal"; (iii) insufficient knowledge of ART side effects due to staff turnover higher than the frequency of training that programmes. The study was conducted as part of the DR Congo national programmes for TB and AIDS and led to the formulation of recommendations about improving, especially through training, the assessment of functional

INTAS Secretary General Dr. J. Sinnaeve visiting Athena experiment.

CERN Multimedia

Patrice Loiez

2002-01-01

Photo 1: INTAS Secretary General Dr. J. Sinnaeve, N. Koulberg, Prof. H. Bokemeyer Head of Physics at INTAS, D.O.Williams and Rolf Landua visiting ATHENA. Photo 2: Prof. H. Bokemeyer Head of Physics at INTAS, INTAS Secretary General J. Sinnaeve and Rolf Landua visiting ATHENA. Photo 3: In the control room of ATHENA, Rolf Landua, Prof. H. Bokemeyer Head of Physics at INTAS and INTAS Secretary General Dr. J. Sinnaeve. INTAS is an independent International Association formed by the European Community, European Union´s Member States and like minded countries acting to preserve and promote the valuable scientific potential of the NIS partner countries through East-West Scientific co-operation.

[Preparation and application of monoclonal antibodies against DR region of Na+-K+-ATPase α1 subunit].

Science.gov (United States)

Yan, Xiaofei; Wu, Litao; DU, Xiaojuan; Li, Jing; Zhang, Fujun; Han, Yan; Lyu, Shemin; Li, Dongmin

2016-12-01

Objective To prepare monoclonal antibodies against DR region (897DVEDSYGQQWTYEQR911) of Na + -K + -ATPase α1 subunit and identify their properties. Methods BALB/c mice were immunized with DR-keyholelimpet hemocyanin (KLH). Splenocytes from the immunized mice were collected and subsequently fused with SP2/0 mouse myeloma cells. Positive hybridoma clones were obtained after cell fusion and selection. ELISA was used to detect DR antibody titer in the cell supernatants. DR region-specific monoclonal antibodies were analyzed by dot blotting, Western blotting and immunofluorescence assay. Na + -K + -ATPase activity was detected by SensoLyte R FDP Protein Phosphatase Assay Kit and the protective effect of the monoclonal antibody against high glucose-induced cell injury was assessed in H9c2 cells. Results Three hybridoma cell lines which secreted stable DR monoclonal antibody were obtained. The strongest positive cell line, named DRm217, was selected to prepare ascites. Dot blotting, Western blotting and immunofluorescence assay showed that DRm217 recognized specially DR region of Na + -K + -ATPase and bound on H9c2 cell membranes. DRm217 stimulated Na + -K + -ATPase activity and alleviated high glucose-induced H9c2 cells injury. Conclusion The monoclonal antibodies against DR region of Na + -K + -ATPase α1 subunit is prepared.

N2R vs. DR Network Infrastructure Evaluation

DEFF Research Database (Denmark)

Pedersen, Jens Myrup; Roost, Lars Jessen; Toft, Per Nesager

2007-01-01

Recent development of Internet-based services has set higher requirements to network infrastructures in terms of more bandwidth, lower delays and more reliability. Theoretical research within the area of Structural Quality of Service (SQoS) has introduced a new type of infrastructure which meet...... these requirements: N2R infrastructures. This paper contributes to the ongoing research with a case study from North Jutland. An evaluation of three N2R infrastructures compared to a Double Ring (DR) infrastructure will provide valuable information of the practical applicability of N2R infrastructures. In order...... to study if N2R infrastructures perform better than the DR infrastructure, a distribution network was established based on geographical information system (GIS) data. Nodes were placed with respect to demographic and geographical factors. The established distribution network was investigated with respect...

Data of evolutionary structure change: 1DR8A-2DHTB [Confc[Archive

Lifescience Database Archive (English)

Full Text Available 1DR8A-2DHTB 1DR8 2DHT A B ------------------------MKVAVLPGDGIGPEV...Chain> 2DHT B 2DHT...50 VAL CA 456 VAL CA 489 SER CA 527 2DHT... B 2DHTB AIEHKRKKVTI GLY CA 352 GLU CA 281 PHE CA 327

Data of evolutionary structure change: 1DR0A-2DHTB [Confc[Archive

Lifescience Database Archive (English)

Full Text Available 1DR0A-2DHTB 1DR0 2DHT A B ------------------------MKVAVLPGDGIGPEV...tryChain> 2DHT B 2DHT...95 HIS CA 348 VAL CA 450 VAL CA 478 2DHT... B 2DHTB YAIEHKRKKVT GLY CA 354 GLU CA 281 PHE CA 323 2DHT

Shepard Award Winners, Part 1: Dr. Stephen Thacker

Centers for Disease Control (CDC) Podcasts

2009-07-22

This podcast highlights the accomplishments of Dr. Stephen Thacker, recipient of the prestigious 2009 CDC Charles C. Shepard Award.  Created: 7/22/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/22/2009.

Shepard Award Winners, Part 2: Dr. Tracie Williams

Centers for Disease Control (CDC) Podcasts

2009-07-29

This podcast highlights the accomplishments of Dr. Tracie Williams, recipient of the prestigious 2009 CDC Charles C. Shepard Award.  Created: 7/29/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/29/2009.

Shepard Award Winners, Part 3: Dr. Larissa Roux

Centers for Disease Control (CDC) Podcasts

2009-09-22

This podcast highlights the accomplishments of Dr. Larissa Roux, recipient of the prestigious 2009 CDC Charles C. Shepard Award.  Created: 9/22/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 9/22/2009.

DR3 regulation of apoptosis of naive T-lymphocytes in children with acute infectious mononucleosis.

Science.gov (United States)

Filatova, Elena Nikolaevna; Anisenkova, Elena Viktorovna; Presnyakova, Nataliya Borisovna; Utkin, Oleg Vladimirovich

2016-09-01

Acute infectious mononucleosis (AIM) is a widespread viral disease that mostly affects children. Development of AIM is accompanied by a change in the ratio of immune cells. This is provided by means of different biological processes including the regulation of apoptosis of naive T-cells. One of the potential regulators of apoptosis of T-lymphocytes is a death receptor 3 (DR3). We have studied the role of DR3 in the regulation of apoptosis of naive CD4 + (nTh) and CD8 + (nCTL) T-cells in healthy children and children with AIM. In healthy children as well as in children with AIM, the activation of DR3 is accompanied by inhibition of apoptosis of nTh. In healthy children, the stimulation of DR3 resulted in the increase in apoptosis of nCTL. On the contrary, in children with AIM, the level of apoptosis of nCTL decreased after DR3 activation, which is a positive contribution to the antiviral immune response. In children with AIM, nCTL are characterized by reduced level of apoptosis as compared with healthy children. These results indicate that DR3 can be involved in the reduction of sensitivity of nCTL to apoptosis in children with AIM.

DR_SEQAN: a PC/Windows-based software to evaluate drug resistance using human immunodeficiency virus type 1 genotypes

Directory of Open Access Journals (Sweden)

Menéndez-Arias Luis

2006-03-01

Full Text Available Abstract Background Genotypic assays based on DNA sequencing of part or the whole reverse transcriptase (RT- and protease (PR-coding regions of the human immunodeficiency virus type 1 (HIV-1 genome have become part of the routine clinical management of HIV-infected individuals. However, the results are difficult to interpret due to complex interactions between mutations found in viral genes. Results DR_SEQAN is a tool to analyze RT and PR sequences. The program output includes a list containing all of the amino acid changes found in the query sequence in comparison with the sequence of a wild-type HIV-1 strain. Translation of codons containing nucleotide mixtures can result in potential ambiguities or heterogeneities in the amino acid sequence. The program identifies all possible combinations of 2 or 3 amino acids that derive from translation of triplets containing nucleotide mixtures. In addition, when ambiguities affect codons relevant for drug resistance, DR_SEQAN allows the user to select the appropriate mutation to be considered by the program's drug resistance interpretation algorithm. Resistance is predicted using a rule-based algorithm, whose efficiency and accuracy has been tested with a large set of drug susceptibility data. Drug resistance predictions given by DR_SEQAN were consistent with phenotypic data and coherent with predictions provided by other publicly available algorithms. In addition, the program output provides two tables showing published drug susceptibility data and references for mutations and combinations of mutations found in the analyzed sequence. These data are retrieved from an integrated relational database, implemented in Microsoft Access, which includes two sets of non-redundant core tables (one for combinations of mutations in the PR and the other for combinations in the RT. Conclusion DR_SEQAN is an easy to use off-line application that provides expert advice on HIV genotypic resistance interpretation. It is

Razmerje med državnim zborom in vlado v Republiki Sloveniji

OpenAIRE

Holobar, Andreja

2016-01-01

V diplomskem delu je bilo obravnavano razmerje med državnim zborom in vlado Republike Slovenije. Državni zbor v Republiki Sloveniji predstavlja nosilca zakonodajne oblasti, vlada Republike Slovenije pa je eden izmed nosilcev izvršne oblasti. Na podlagi delitve oblasti, ki je opredeljena tudi v Ustavi Republike Slovenije, naj bi bili omenjeni veji oblasti ločeni, njuno razmerje pa uravnavajo mehanizmi ravnovesij in zavor, ki so prav tako opredeljeni v Ustavi. Uporabljeni mehanizmi naj bi zagot...

Konsep Pendidikan Akhlak dan Dakwah dalam Perspektif Dr. KH. Zakky Mubarak, MA

Directory of Open Access Journals (Sweden)

Muchtar Muchtar

2017-09-01

Full Text Available Research aims to understand role, and the concept of education and dakwah in perspective Dr. KH. Zakky Mubarak, MA. This research departs from looking at the phenomenon of human life is increasingly complex, entered the modern life and globalization present and the future, wich is characterized by technical and professional paced lives, is forecast to many people ignore the moral and religious in individual and social life. The concept of moral education in the perspective of Dr. KH. Zakky Mubarak, MA that establishes the character of the learners, provide good role models, develop the moral high level, and then apply the knowledge of good character and exemplary in real life so it can become an ingrained habit. The concept of dakwah in perspective Dr. KH. Zakky Mubarak, MA at least two steps that need to be understood by a preacher, first that of bringing the wisdom, it means explaining the wisdoms contained in worship and other Islamic activities without patronizing impression, meaning a preacher should put the words and appropriate sentence appropriate to the circumstances . The second is to mau'idlah hasanah , means giving advice that touch the heart so that the message can be embedded in the memories of audience. Dr. KH. Zakky Mubarak, MA is one of the Nahdlatul Ulama cleric who spend their time preaching, either through a lecture or through scientific papers, scientific papers written contains a lot of moral education that can be used as a reference.  Keywords: Concept of Education and Dakwah, Zakky Mubarak, Nahdlatul Ulama Abstrak Penelitian ini bertujuan untuk mengetahui peran, serta konsep pendidikan akhlak dan dakwah dalam perspektif Dr. KH. Zakky Mubarak, MA. Kesimpulan penelitian ini bahwa Konsep pendidikan akhlak dalam perspektif Dr. KH. Zakky Mubarak, MA yaitu menanamkan pemahaman tentang akhlak terhadap peserta didik, memberikan keteladanan yang baik, mengembangkan pada akhlak tingkat tinggi, dan kemudian mengaplikasikan

Winston Churchill (1874-1965), Dr Robson Roose, MD Brux, FRCPE (1848-1905) and Dr Joseph Rutter, MD Lond, MRCP (1834-1913): Treatment for pneumonia in March 1886.

Science.gov (United States)

Vale, J Allister; Scadding, John W

2018-01-01

This paper will review Winston Churchill's severe respiratory illness in March 1886 when he developed pneumonia of the right lung as an 11-year-old boy. Winston was treated supportively with 'nourishment, stimulants [probably alcohol] and close watching' at his school by the 'celebrated' family physician, Dr Robson Roose, with the assistance of Dr Joseph Rutter. Roose was exemplary in his commitment to his young patient and assiduous in informing Lord Randolph Churchill of his son's clinical progress by letter.

A Fear Management Approach to Counter-Terrorism

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Tinka Veldhuis

2012-02-01

Full Text Available Spreading fear is the essence of terrorism. Terrorists exploit fear by terrorising the target audience into concessions. Understanding how feelings of fear influence the way people feel, think and act is therefore an important starting point to explore how individuals and societies can learn how to cope with fear of terrorism. In this Policy Brief, Research Fellows Prof. Dr. Edwin Bakker and Dr. Tinka Veldhuis explore the dynamics of fear in response to terrorism, and emphasise the importance of integrating initiatives to manage fear of terrorism and reduce its negative consequences into overarching counter-terrorism strategies. It argues that societies can benefit greatly from promoting resilience and a fear management approach to counter-terrorism.

Optimization on scoliosis examination on Canons DR system

DEFF Research Database (Denmark)

Precht, Helle

2007-01-01

recordings of scoliosis today are carried out on CR systems even though most radiological departments have DR systems available. Theoretically speaking the two modalities are similar regarding dose and image quality. In this project consequently, the focus will be to obtain images of equal dose and quality...... at a DR system when using different receptors during the exam. This is a completely new opportunity, as it has earlier been difficult to compare distinct scintilators connected to the receptors due to unlike processing of the image. Given that Canon have released a receptor with CsI scintilator we...... in which theory is used as a background for the test setup and later audit appraisal. Two tests are carried out on two different hospitals with each their receptor, and afterwards the results are compared. To guarantee comparable tests the results are verified through status checks and statistical t...

The Learning Organization and Some Other Modern Theories of Management

International Nuclear Information System (INIS)

Sugarman, Barry

2003-01-01

In the first part, Dr Sugarman reviewed several recent theories of management and their relevance to NPP management. These theories encompass basic aspects like bureaucracy, un-bureaucracy, quality and excellence, re-engineering, knowledge management, emotional intelligence and learning organisation. Dr Sugarman discussed evolution from the Old Paradigm (Bureaucracy) to the New One (Learning Organization), defining the main aspects of both models, that can be summarises primarily in regards to strategy and structure. In terms of strategy, the new paradigm moves away from being largely inflexible to a much more dynamic environment whereby innovation is encouraged as opposed to performing in the prescribed manner whether suitable or not. The structural changes in the new model are also evident. There has been a marked move away from a hierarchical 'top down' approach to a much flatter structure that encourages less empire building and more openness between teams of various. This ensures a much greater understanding by the whole organisation of what is happening. Dr Sugarman centred his talk on the new model and how this has affected the development of the current situation. The Learning Organisation, according to the definition of Peter Senge in The Fifth Discipline (1990), is an organisation where people continually expand their capacity to create results they truly desire, and where the people are continually learning how to learn together. The movements behind increasing quality introduced a new model into industry based on Production, where workers became responsible for quality assurance instead of quality controls being reviewed by inspectors. All the employees share responsibility for learning how to improve continuously. That means, complete involvement of all staff. Following on from this, the Quality Revolution made appearance and was driven by extra attention to the customer. Out-sourcing became common and the 'Internal customer' became more common. All

Herniated Nucleus Pulposus in Dr. Hasan Sadikin General Hospital Bandung Indonesia

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Annisa Ikhsanawati

2015-06-01

Full Text Available Background: Herniated nucleus pulposus (HNP is one of the most common diseases of the spine. For an optimal management and prevention, there’s a need for data on factors related to the onset of complaints because this disease lowers the quality of life and increases morbidity. This study is aimed to see the scale and pattern of the HNP in Dr. Hasan Sadikin General Hospital, Bandung. Methods: This is a descriptive study with the design of case series, data was obtained from medical records of patients with the diagnosis of HNP in the inpatient care of Dr. Hasan Sadikin General Hospital in the period of 2007–2011. Results: According to the study on 79 patients, with 43 men and 36 women, the highest incidence was at the age group of 51–60 years old (31.6% and most common occupation was civil servant (11.4%. The most common clinical symptoms were sciatica (51.9% and low back pain (51.9%. Most frequent location was in the lumbar vertebrae at the level of L5–S1 (58.2%. Trauma was found to be the highest relatable history in the patients (39.2%. Therapy of choice was primarily conservative (58.2% and most patients went home after the progression (84.8%. The year 2007 showed the highest prevalence of HNP at 25.3%. The most common clinical symptoms were sciatica (51.9% and low back pain (51.9% Conclusions: The most common clinical symptoms were sciatica and low back pain. Most frequent location was in the lumbar vertebrae at the level L5–S1.

Načini podpore prevajanju v državah Evropske unije

OpenAIRE

Šimenc, Agata

2017-01-01

Države Evropske unije poznajo različne oblike podpore, ki pomagajo pri spodbujanju in financiranju prevajanja literature v tuje jezike in s tem skrbijo za promocijo države, njene kulture, zlasti pa njene literature in njenih literarnih ustvarjalcev v tujini. Ti sistemi podpore so pomembni predvsem za literature, ki nastajajo v manj razširjenih jezikih in zato težje pridejo do tujih bralcev. Naloga primerja različne podpore prevajanju nacionalnih leposlovij v tuje jezike, ki obstajajo v različ...

GenoType HelicoDR test in the determination of antimicrobial resistance of Helicobacter pylori in Korea.

Science.gov (United States)

Lee, Jung Won; Kim, Nayoung; Nam, Ryoung Hee; Park, Ji Hyun; Choi, Yoon Jin; Kim, Jung Mogg; Kim, Joo Sung; Jung, Hyun Chae

2014-09-01

Antimicrobial resistance of Helicobacter pylori is most important factor in eradication success. GenoType HelicoDR test has been developed for rapid detection of antimicrobial resistance. The present study evaluated the clinical usefulness of GenoType HelicoDR test in Korea. To detect 23S rRNA for clarithromycin resistance and gyrA mutations for fluoroquinolone resistance, both DNA sequencing after minimal inhibitory test (MIC) and GenoType HelicoDR test were performed in H. pylori isolates from the gastric mucosa of 101 patients. The eradication results of clarithromycin and moxifloxacin-containing triple therapy were evaluated by the 23S rRNA and gyrA mutations. For 42 isolates with A2143G mutation by GenoType HelicoDR, 83.3% (35/42) of concordance rate was estimated with DNA sequencing method and 85.7% (36/42) for MIC test. For 43 isolates with N87K mutation by GenoType HelicoDR, 71.1% (31/43) of concordance rate was estimated with DNA sequencing and 88.4% (38/43) for MIC test. The sensitivity and specificity of GenoType HelicoDR test in determination of 23S rRNA mutation were 94.9% and 87.1%, and those of gyrA 98.2% and 80.0%. The sensitivity and specificity of GenoType HelicoDR test in determination of clarithromycin resistance based on MIC test were 55.0% and 80.0%, for fluoroquinolone 74.4% and 70.0%. GenoType HelicoDR test is useful to determine mutations responsible for clarithromycin or fluoroquinolone-containing eradication failure but has a limitation for the clinical applicability in determination of resistance.

PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP, HADRON STRUCTURE FROM LATTICE QCD, MARCH 18 - 22, 2002, BROOKHAVEN NATIONAL LABORATORY.

Energy Technology Data Exchange (ETDEWEB)

BLUM, T.; BOER, D.; CREUTZ, M.; OHTA, S.; ORGINOS, K.

2002-03-18

The RIKEN BNL Research Center workshop on ''Hadron Structure from Lattice QCD'' was held at BNL during March 11-15, 2002. Hadron structure has been the subject of many theoretical and experimental investigations, with significant success in understanding the building blocks of matter. The nonperturbative nature of QCD, however, has always been an obstacle to deepening our understanding of hadronic physics. Lattice QCD provides the tool to overcome these difficulties and hence a link can be established between the fundamental theory of QCD and hadron phenomenology. Due to the steady progress in improving lattice calculations over the years, comparison with experimentally measured hadronic quantities has become important. In this respect the workshop was especially timely. By providing an opportunity for experts from the lattice and hadron structure communities to present their latest results, the workshop enhanced the exchange of knowledge and ideas. With a total of 32 registered participants and 26 talks, the interest of a growing community is clearly exemplified. At the workshop Schierholz and Negele presented the current status of lattice computations of hadron structure. Substantial progress has been made during recent years now that the quenched results are well under control and the first dynamical results have appeared. In both the dynamical and the quenched simulations the lattice results, extrapolated to lighter quark masses, seem to disagree with experiment. Melnitchouk presented a possible explanation (chiral logs) for this disagreement. It became clear from these discussions that lattice computations at significantly lighter quark masses need to be performed.

Radiation protection measures during the decommissioning of DR 2

International Nuclear Information System (INIS)

Larsen, Thommy Ingemann; Hedemann Jensen, Per; Sogaard-Hansena, Jens; Lauridsen, Bente

2008-01-01

DR 2 (Danish Reactor 2), one of the research reactors at the Riso site, has been in the process of being decommissioned during the last two years. The decommissioning will be completed in 2008. The reactor went critical for the first time in late 1958 and was shut down in 1975. The construction was a 5 MW light-water moderated and cooled tank type reactor. Although the process of decommissioning was formally initiated in 2005, it was preceded by a characterization project with the purpose of determining activity contents in key materials and dose rates at relevant spots in the reactor. The paper describes the removal of neutron beam plugs, grid plate and a thermal column with focus on radiation protection issues. The primary objective is, however, to describe the measures taken to control radiation doses during the removal of the reactor block concrete and the reactor tank.The demolition and removal of concrete was done by an external contractor. The contractor had to comply with a comprehensive set of requirements. This included splitting activated concrete from concrete containing activities below clearance levels with no use of fluids of any kind, as the risk of not being able to control diffusion of contaminated fluids was an important issue. The experience from the decommissioning of the DR 1 reactor in 2005 showed that water-cooled cutting made it very difficult to monitor the levels of air contamination as the filters of the air monitors were blocked frequently. Certainly, dry cutting turned out to be a great technical challenge to the external contractor. Another demand was that the work should take place inside a de-pressurized containment in order to control air contamination and thereby minimize internal doses. The experience gathered from the practical implementation of dose reducing measures will be discussed. Problems involving the use of external contractors will be discussed, including training of personnel with no prior knowledge of radioactivity

Research on image reconstruction of DR/SSCT security inspection system

International Nuclear Information System (INIS)

Li Jian; Cong Peng

2008-01-01

On the basis of DR (Digital Radiography)/CT security inspection system, DR/SSCT (single slice spiral CT) security inspection system was developed. This spiral CT system can improve the CT system's drawbacks. The research work includes in replacing the former data acquisition system by a new system which can acquire projection data of multi-slices and devising the SSCT reconstruction algorithms. Simulation experiments and practical experiments were devised to contrast several algorithms. Interpolation technique was operated in detectors data in order to improve the algorithms. In conclusion, the system exploits an algorithm of weighted average of 360 degree LI (Linear Interpolation) and JH-HI (Jiang Hsieh-Half scan Interpolation). (authors)

Dr. House: Patología dual en el médico

Directory of Open Access Journals (Sweden)

Mariano A. BELLINA

2016-09-01

Full Text Available Dr. House es una serie dramática estadounidense cuyo personaje central es el Dr. Gregory House, médi? co que dirige una unidad de diagnóstico (con otros tres doctores en el Hospital Universitario Princeton? Plainsboro, en Nueva Jersey. Dr. House utiliza un proceso lógico especial como base para llegar al diagnóstico. La Unidad que dirige el Dr. House trata pacientes que han sido evaluados previamente por otros doctores sin haber alcanzado un diagnóstico. Los diagnósticos oscilan desde algunos muy comunes a enfermedades raras. House no respeta las reglas y procedimientos comunes en la Medicina tradicional, tiene conflictos interpersonales graves (así como falta de empatía y no muestra interés por otras prácticas clínicas que no sean las suyas. Sufre un dolor crónico intenso en la pierna derecha por el que comienza a prescribirse Vicodin® (hidrocodona, al que acaba haciéndose dependiente. Nuestra hipótesis es que House es un caso típico de patología dual, PD (coexistencia de trastorno por uso de sustancias y otra enfermedad mental, en concreto: de dependencia de opiáceos y trastorno mixto de personalidad (comparte rasgos del trastorno de la personalidad antisocial y narcisista. La PD no es infrecuente en médicos dada la demora en pedir ayuda y la fácil accesibilidad a algunas sustancias.

Stemcell Information: SKIP000138 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 代 Riken Center for Developmental Biology (Riken CDB) 理研発生再生科学総合研究センター (理研CDB) Riken Center for Developmental... Biology (Riken CDB) 理研発生再生科学総合研究センター (理研CDB) Masayo Takahashi 高橋　政代 Available Ri

Dr John McLennan MD (Aberdeen), FRCP (Lond) (1801-1874) and the Medical School of Bombay that failed.

Science.gov (United States)

Pandya, Sunil K

2017-01-01

In 1826, Dr John McLennan was asked by Governor Mounstuart Elphinstone of Bombay to set up the first school to teach modern medicine to Indian citizens. He was expected to create textbooks on a variety of subjects in local languages and teach medicine to poorly educated students in their native tongues. Despite his valiant efforts, the school was deemed a failure and was abolished by the Government in 1832. Sir Robert Grant, appointed Governor of Bombay in 1835, analysed records pertaining to this medical school and concluded that the school failed since Dr McLennan was not provided the assistance he needed and as his suggestions for access to a hospital to teach medicine were not heeded. Dr McLennan provided able support to Dr Charles Morehead on his appointment as Principal and Professor of Medicine at the newly created Grant Medical College in Bombay in 1845. Dr Morehead dedicated his classic 'Clinical researches on diseases in India' to Dr McLennan. Dr McLennan headed the Board of Examiners created to assess the competence of the first batch of medical students emerging from this College. The system of evaluation set up by him remains admirable. Dr McLennan retired from service as Physician-General, full of honours.

Annual report of the Institute of Physical and Chemical Research, for fiscal 1998

International Nuclear Information System (INIS)

1999-01-01

This annual report describes the abstracts of researches and oral presentations and papers reported as the results for fiscal 1998 in each laboratory of RIKEN (the Institute of Physical and Chemical Research). Moreover, the themes of special project funding for basic science, grant research, contract research, industrial properties, research subjects of special postdoctoral researchers and junior research associate and technology research subjects of technology research fellow are inserted. The abstract of researches, oral presentations and publications reported by Frontier Research Program, Brain Science Institute, Riken and Riken Genomic Science Center are contained. Riken Symposia and Symposia Sponsored by Riken are explained. (S.Y.)

Exclusive Interview with Dr. Lassina Zerbo, Executive Secretary of the CTBTO

International Nuclear Information System (INIS)

Hautecouverture, Benjamin

2013-01-01

Dr Lassina Zerbo, the new Executive Secretary of the Comprehensive Nuclear-Test-Ban Treaty Organisation (CTBTO), was invited to speak at the Foundation for Strategic Research on 19 December 2013. Before the event, Dr. Zerbo spoke to Non-Proliferation Monthly, outlining the major axes of his strategy for the CTBTO over the coming years, his thoughts on the prospects for the Treaty's entry into force and on the role that he believes this instrument should fulfil in the political inter-State dialogue and in bilateral and multilateral diplomatic negotiation processes

Interview with Dr Anna Matamala

Directory of Open Access Journals (Sweden)

Lucinea Marcelino Villela

2016-09-01

In this interview, which took place in June 2016, Dr Anna Matamala described some details about her long professional experience in Audiovisual Translation, especially in dubbing from English into Catalan, and we talked about many other things like her interest in lexicography, her point of view on some contemporary topics in Audiovisual Translation Studies: the use of technology, the relation between AVT and Accessibility Studies, AVT and Filmmaking fields, the importance of keeping in touch with other countries and even continents outside Europe, and she also gave some advice to the new generation of Translation students.

Interview with Dr Anna Matamala

Directory of Open Access Journals (Sweden)

Lucinea Marcelino Villela

2016-12-01

Full Text Available In this interview, which took place in June 2016, Dr Anna Matamala described some details about her long professional experience in Audiovisual Translation, especially in dubbing from English into Catalan, and we talked about many other things like her interest in lexicography, her point of view on some contemporary topics in Audiovisual Translation Studies: the use of technology, the relation between AVT and Accessibility Studies, AVT and Filmmaking fields, the importance of keeping in touch with other countries and even continents outside Europe, and she also gave some advice to the new generation of Translation students.

The great neurosis of Dr. Joseph Gerard.

Science.gov (United States)

Lefrère, Jean-Jacques; Rouillon, Frédéric

2013-01-01

The Great Neurosis, of Dr. Joseph Gerard, was published in 1889 in Paris. The book, intended for the general public, shows the different varieties of neuroses through picturesque and instructive examples. Its scientific and medical value is poor, but provides us with the various meanings of the word 'neurosis' in the late nineteenth century. Copyright © 2013 S. Karger AG, Basel.

Underwater Gliders by Dr. Kevin Smith [video

OpenAIRE

Naval Postgraduate School Physics

2015-01-01

NPS Physics NPS Physics Research Projects Underwater glider research is currently underway in the physics department at the naval postgraduate in Monterey Ca. Dr. Kevin Smith is a specialist in underwater acoustics and sonar systems. He and his team are currently focused on autonomous underwater gliders and developing systems capable of detecting parameters in the ocean and listening for various sources of sound.

Verification of the code DYN3D/R with the help of international benchmarks

International Nuclear Information System (INIS)

Grundmann, U.; Rohde, U.

1997-10-01

Different benchmarks for reactors with quadratic fuel assemblies were calculated with the code DYN3D/R. In this report comparisons with the results of the reference solutions are carried out. The results of DYN3D/R and the reference calculation for the eigenvalue k eff and the power distribution are shown for the steady-state 3-dimensional IAEA-Benchmark. The results of NEACRP-Benchmarks on control rod ejections in a standard PWR were compared with the reference solutions published by the NEA Data Bank. For assessing the accuracy of DYN3D/R results in comparison to other codes the deviations to the reference solutions are considered. Detailed comparisons with the published reference solutions of the NEA-NSC Benchmarks on uncontrolled withdrawal of control rods are made. The influence of the axial nodalization is also investigated. All in all, a good agreement of the DYN3D/R results with the reference solutions can be seen for the considered benchmark problems. (orig.) [de

Establishment of HLA-DR4 transgenic mice for the identification of CD4+ T cell epitopes of tumor-associated antigens.

Directory of Open Access Journals (Sweden)

Junji Yatsuda

Full Text Available Reports have shown that activation of tumor-specific CD4(+ helper T (Th cells is crucial for effective anti-tumor immunity and identification of Th-cell epitopes is critical for peptide vaccine-based cancer immunotherapy. Although computer algorithms are available to predict peptides with high binding affinity to a specific HLA class II molecule, the ability of those peptides to induce Th-cell responses must be evaluated. We have established HLA-DR4 (HLA-DRA*01:01/HLA-DRB1*04:05 transgenic mice (Tgm, since this HLA-DR allele is most frequent (13.6% in Japanese population, to evaluate HLA-DR4-restricted Th-cell responses to tumor-associated antigen (TAA-derived peptides predicted to bind to HLA-DR4. To avoid weak binding between mouse CD4 and HLA-DR4, Tgm were designed to express chimeric HLA-DR4/I-E(d, where I-E(d α1 and β1 domains were replaced with those from HLA-DR4. Th cells isolated from Tgm immunized with adjuvant and HLA-DR4-binding cytomegalovirus-derived peptide proliferated when stimulated with peptide-pulsed HLA-DR4-transduced mouse L cells, indicating chimeric HLA-DR4/I-E(d has equivalent antigen presenting capacity to HLA-DR4. Immunization with CDCA155-78 peptide, a computer algorithm-predicted HLA-DR4-binding peptide derived from TAA CDCA1, successfully induced Th-cell responses in Tgm, while immunization of HLA-DR4-binding Wilms' tumor 1 antigen-derived peptide with identical amino acid sequence to mouse ortholog failed. This was overcome by using peptide-pulsed syngeneic bone marrow-derived dendritic cells (BM-DC followed by immunization with peptide/CFA booster. BM-DC-based immunization of KIF20A494-517 peptide from another TAA KIF20A, with an almost identical HLA-binding core amino acid sequence to mouse ortholog, successfully induced Th-cell responses in Tgm. Notably, both CDCA155-78 and KIF20A494-517 peptides induced human Th-cell responses in PBMCs from HLA-DR4-positive donors. Finally, an HLA-DR4 binding DEPDC1191

Dr Abraham Pais, 82, physicist and science historian dies

CERN Document Server

Glanz, J

2000-01-01

Obituary of Dr. Pais who died of heart failure in Copenhagen. He helped build the conceptual foundations of particle physics and then became a science historian, writing a critically acclaimed biography of Einstein (1 pg).

The induction of autoimmune hepatitis in the human leucocyte antigen-DR4 non-obese diabetic mice autoimmune hepatitis mouse model.

Science.gov (United States)

Yuksel, M; Xiao, X; Tai, N; Vijay, G M; Gülden, E; Beland, K; Lapierre, P; Alvarez, F; Hu, Z; Colle, I; Ma, Y; Wen, L

2016-11-01

Autoimmune hepatitis (AIH) is a chronic liver disease characterized by progressive inflammation, female preponderance and seropositivity for autoantibodies such as anti-smooth muscle actin and/or anti-nuclear, anti-liver kidney microsomal type 1 (anti-LKM1) and anti-liver cytosol type 1 (anti-LC1) in more than 80% of cases. AIH is linked strongly to several major histocompatibility complex (MHC) alleles, including human leucocyte antigen (HLA)-DR3, -DR7 and -DR13. HLA-DR4 has the second strongest association with adult AIH, after HLA-DR3. We investigated the role of HLA-DR4 in the development of AIH by immunization of HLA-DR4 (DR4) transgenic non-obese diabetic (NOD) mice with DNA coding for human CYP2D6/FTCD fusion autoantigen. Immunization of DR4 mice leads to sustained mild liver injury, as assessed biochemically by elevated alanine aminotransferase, histologically by interface hepatitis, plasma cell infiltration and mild fibrosis and immunologically by the development of anti-LKM1/anti-LC1 antibodies. In addition, livers from DR4 mice had fewer regulatory T cells (T regs ), which had decreased programmed death (PD)-1 expression. Splenic T regs from these mice also showed impaired inhibitory capacity. Furthermore, DR4 expression enhanced the activation status of CD8 + T cells, macrophages and dendritic cells in naive DR4 mice compared to naive wild-type (WT) NOD mice. Our results demonstrate that HLA-DR4 is a susceptibility factor for the development of AIH. Impaired suppressive function of T regs and reduced PD-1 expression may result in spontaneous activation of key immune cell subsets, such as antigen-presenting cells and CD8 + T effectors, facilitating the induction of AIH and persistent liver damage. © 2016 British Society for Immunology.

The induction of autoimmune hepatitis in the human leucocyte antigen‐DR4 non‐obese diabetic mice autoimmune hepatitis mouse model

Science.gov (United States)

Yuksel, M.; Xiao, X.; Tai, N.; Vijay, G. M.; Gülden, E.; Beland, K.; Lapierre, P.; Alvarez, F.; Hu, Z.; Colle, I.; Ma, Y.

2016-01-01

Summary Autoimmune hepatitis (AIH) is a chronic liver disease characterized by progressive inflammation, female preponderance and seropositivity for autoantibodies such as anti‐smooth muscle actin and/or anti‐nuclear, anti‐liver kidney microsomal type 1 (anti‐LKM1) and anti‐liver cytosol type 1 (anti‐LC1) in more than 80% of cases. AIH is linked strongly to several major histocompatibility complex (MHC) alleles, including human leucocyte antigen (HLA)‐DR3, ‐DR7 and ‐DR13. HLA‐DR4 has the second strongest association with adult AIH, after HLA‐DR3. We investigated the role of HLA‐DR4 in the development of AIH by immunization of HLA‐DR4 (DR4) transgenic non‐obese diabetic (NOD) mice with DNA coding for human CYP2D6/FTCD fusion autoantigen. Immunization of DR4 mice leads to sustained mild liver injury, as assessed biochemically by elevated alanine aminotransferase, histologically by interface hepatitis, plasma cell infiltration and mild fibrosis and immunologically by the development of anti‐LKM1/anti‐LC1 antibodies. In addition, livers from DR4 mice had fewer regulatory T cells (Tregs), which had decreased programmed death (PD)‐1 expression. Splenic Tregs from these mice also showed impaired inhibitory capacity. Furthermore, DR4 expression enhanced the activation status of CD8+ T cells, macrophages and dendritic cells in naive DR4 mice compared to naive wild‐type (WT) NOD mice. Our results demonstrate that HLA‐DR4 is a susceptibility factor for the development of AIH. Impaired suppressive function of Tregs and reduced PD‐1 expression may result in spontaneous activation of key immune cell subsets, such as antigen‐presenting cells and CD8+ T effectors, facilitating the induction of AIH and persistent liver damage. PMID:27414259

Dr. Monaco Examines Lab-on a-Chip

Science.gov (United States)

2003-01-01

Dr. Lisa Monaco, Marshall Space Flight Center's (MSFC's) project scientist for the Lab-on-a-Chip Applications Development (LOCAD) program, examines a lab on a chip. The small dots are actually ports where fluids and chemicals can be mixed or samples can be collected for testing. Tiny channels, only clearly visible under a microscope, form pathways between the ports. Many chemical and biological processes, previously conducted on large pieces of laboratory equipment, can now be performed on these small glass or plastic plates. Monaco and other researchers at MSFC in Huntsville, Alabama, are customizing the chips to be used for many space applications, such as monitoring microbes inside spacecraft and detecting life on other planets. The portable, handheld Lab-on-a Chip Application Development Portable Test System (LOCAD-PTS) made its debut flight aboard Discovery during the STS-116 mission launched December 9, 2006. The system allowed crew members to monitor their environment for problematic contaminants such as yeast, mold, and even E.coli, and salmonella. Once LOCAD-PTS reached the International Space Station (ISS), the Marshall team continued to manage the experiment, monitoring the study from a console in the Payload Operations Center at MSFC. The results of these studies will help NASA researchers refine the technology for future Moon and Mars missions. (NASA/MSFC/D.Stoffer)

FIRST INTERFEROMETRIC IMAGES OF THE 36 GHz METHANOL MASERS IN THE DR21 COMPLEX

International Nuclear Information System (INIS)

Fish, Vincent L.; Muehlbrad, Talitha C.; Pratap, Preethi; Sjouwerman, Lorant O.; Strelnitski, Vladimir; Pihlstroem, Ylva M.; Bourke, Tyler L.

2011-01-01

Class I methanol masers are believed to be produced in the shock-excited environment around star-forming regions. Many authors have argued that the appearance of various subsets of class I masers may be indicative of specific evolutionary stages of star formation or excitation conditions. Until recently, however, no major interferometer was capable of imaging the important 36 GHz transition. We report on Expanded Very Large Array observations of the 36 GHz methanol masers and Submillimeter Array observations of the 229 GHz methanol masers in DR21(OH), DR21N, and DR21W. The distribution of 36 GHz masers in the outflow of DR21(OH) is similar to that of the other class I methanol transitions, with numerous multitransition spatial overlaps. At the site of the main continuum source in DR21(OH), class I masers at 36 and 229 GHz are found in virtual overlap with class II 6.7 GHz masers. To the south of the outflow, the 36 GHz masers are scattered over a large region but usually do not appear coincident with 44 GHz masers. In DR21W, we detect an 'S-curve' signature in Stokes V that implies a large value of the magnetic field strength if interpreted as due to Zeeman splitting, suggesting either that class I masers may exist at higher densities than previously believed or that the direct Zeeman interpretation of S-curve Stokes V profiles in class I masers may be incorrect. We find a diverse variety of different maser phenomena in these sources, suggestive of differing physical conditions among them.

Electrodiagnosis in the management of focal neuropathies: the "WOG" syndrome.

Science.gov (United States)

Brown, W F; Dellon, A L; Campbell, W W

1994-11-01

The role of electrodiagnosis in managing patients with focal neuropathies is discussed from the differing perspectives of a peripheral nerve surgeon and a practitioner of electrodiagnostic medicine. Both clinical evaluation and electrodiagnosis are useful methodologies, each having limitations. Dr. Dellon labels the overreliance on electrodiagnosis and the "WOG" (Word of God) syndrome, and describes its signs, symptoms, and treatment. Dr. Brown contends Dr. Dellon's crusade is misdirected. The exchange is an eloquent polemic on the virtues and foibles of these different approaches to evaluating peripheral nerve function and the imperative to practice them in a complementary rather than a contentious manner.

Životní jubileum RNDr. Tadeáše Czudka, DrSC

OpenAIRE

Hrádek, M. (Mojmír)

2012-01-01

Dr.Tadeaš Czudek,DrSc is an eminent Czech geomorphologist who turned eighty on April 1st, 2012. In years 1956 - 1993 he worked in the Institute of Geography of the Czechoslovak Academy of Science in Brno, part of this time as head of departement of geomorphology. He was interesting in periglacial and climatic geomorphology particularly in development of planation surfaces and specially cryopediments and significance of permafrost. He published more than 240 papers and other works and ...

DR Experiments in the 60 years since the Bates paper

International Nuclear Information System (INIS)

Johnsen, Rainer

2011-01-01

About 60 years have passed since David Bates in a 1950 Physical Review Letter to the Editor first clarified the dissociative recombination mechanism (DR) of molecular ions and provided the conceptual basis for the process that plays an important role in the ionospheres of Earth and other planets, the interstellar medium, and electrical discharges. His visionary (and characteristically 'terse') thumbnail sketch of the DR mechanism only hinted at the subtleties that have kept atomic theorists and experimentalists busy for many years. In my talk, I will focus on experiments on N 2 + recombination, beginning with plasma afterglows, and then move on to the 'after'-afterglow period that is now dominated by the powerful storage-ring methods.

Annual report of the Institute of Physical and Chemical Research, for fiscal 1999

International Nuclear Information System (INIS)

2000-01-01

The research activities in the Institute of Physical and Chemical Research (RIKEN) for the fiscal year 1999 were briefly described in this report. In addition, the research papers published in the year from the laboratories in RIKEN Wako Main Campus, RIKEN Tsukuba Research Center of Life Science and RIKEN Harima Institute were presented. Moreover, ten special research projects for basic science are now progressing on the following themes: photosynthetic science (artificial photosynthesis and the mechanism of photosynthesis), biodesign research (cellular function system, membranous function system), coherent science research (coherent control for free electron, quantum processing, structural control and coherent molecular interaction), research on multi-bioprobes (development of multi-functional bioactive compounds), research on essential reaction (stereo-control and energy control), atomic-scale sciengineering (phase 2 study), MR science research (phase 2 study), slow quantum beam production of ultra slow highly charged ions and ecomolecular science research (material conversion and biological/chemical conversion for environmental compounds). The research activities of RIKEN Brain Science Institute were also outlined and RIKEN Genomic Sciences Center were also outlined. In the year, RIKEN symposium was held 38 times by various laboratories. Here, the themes of these symposia were listed as well as those of international symposia sponsored by RIKEN Institute. (M.N.)

Lasing characteristics of 1.5 μm GaInAsP-InP SCH-BIG-DR lasers

International Nuclear Information System (INIS)

Shim, J.I.; Komori, K.; Arai, S.; Arima, I.; Suematsu, Y.; Somchai, R.

1991-01-01

This paper reports that higher differential quantum efficiency η df , smaller chirp Δλ, narrower linewidth Δν, and high coupling efficiency C out between active and passive regions of 1.5 μm GaInAsP/In PSCH-BIG-Dr lasers with a thin active layer and asymmetric gratings are experimentally demonstrated by a comparison of those properties of DFB lasers from the same wafer. A submode suppression ratio (SMSR) of more than 39 dB at 1.7 times the threshold current and a C out of almost 100% in the SCH-BIG-DR lasers indicated that a separate-confinement-heterostructure (SCH) with a thin active layer and a bundle-integrated-guide (BIG) structure are quite adequate to realize high-performance distributed reflector (DR-type lasers) a two times larger η df and 16 times larger front-to-rear output ratio (FROR) of SCH-BIG-DR lasers that those of DFB lasers showed the superiority of DR lasers for high-efficiency operation. Furthermore, superior spectral characteristics of the SCH-BIG-DR laser in comparison to those of conventional DFB lasers, i.e., only about a half of chirping under a rapid direction modulation, as well as 1/5 of the linewidth-power product, were also obtained, which originated from the smaller effective linewidth enhancement factor α eff of the DR laser

Dr Skateboard's Action Science: Teaching Physics in Context

Science.gov (United States)

Robertson, William H.

2009-01-01

In order to create student interest and promote new connections to the understanding of fundamental physics concepts, there is a need for new approaches and methods that are both contemporary and relevant. Dr Skateboard's Action Science, a curriculum supplement comprising video instruction and classroom activities, is an example that focuses on…

Dr.LiTHO: a development and research lithography simulator

Science.gov (United States)

Fühner, Tim; Schnattinger, Thomas; Ardelean, Gheorghe; Erdmann, Andreas

2007-03-01

This paper introduces Dr.LiTHO, a research and development oriented lithography simulation environment developed at Fraunhofer IISB to flexibly integrate our simulation models into one coherent platform. We propose a light-weight approach to a lithography simulation environment: The use of a scripting (batch) language as an integration platform. Out of the great variety of different scripting languages, Python proved superior in many ways: It exhibits a good-natured learning-curve, it is efficient, available on virtually any platform, and provides sophisticated integration mechanisms for existing programs. In this paper, we will describe the steps, required to provide Python bindings for existing programs and to finally generate an integrated simulation environment. In addition, we will give a short introduction into selected software design demands associated with the development of such a framework. We will especially focus on testing and (both technical and user-oriented) documentation issues. Dr.LiTHO Python files contain not only all simulation parameter settings but also the simulation flow, providing maximum flexibility. In addition to relatively simple batch jobs, repetitive tasks can be pooled in libraries. And as Python is a full-blown programming language, users can add virtually any functionality, which is especially useful in the scope of simulation studies or optimization tasks, that often require masses of evaluations. Furthermore, we will give a short overview of the numerous existing Python packages. Several examples demonstrate the feasibility and productiveness of integrating Python packages into custom Dr.LiTHO scripts.

Study methodology and diabetes control in patients from the non-English diabetes management project (NEDMP).

Science.gov (United States)

Dirani, Mohamed; Dang, Trung M; Xie, Jing; Gnanasekaran, Sivashanth; Nicolaou, Theona; Rees, Gwyneth; Fenwick, Eva; Lamoureux, Ecosse L

2017-03-01

To describe the clinical characteristics of non-English speaking patients from the Diabetes Management Project (NEDMP), and compare their diabetes management and severity of diabetic retinopathy (DR) with the English-speaking DMP sample (EDMP). A prospective study was conducted on non-English speaking adults with diabetes who attended the Royal Victorian Eye and Ear Hospital. 136 (90.1%) non-English speaking adults were assessed, with a mean age of 72.2 years (range: 50-88 years); 74 (54.4%) were male. Participants completed interviewer-administered questionnaires and underwent visual acuity, fundus photography, optical coherence tomography, biochemistry and anthropometric measurements. The EDMP assessed 609 patients in 2009 using a similar protocol. Type and duration of diabetes, diabetes control and diabetic retinopathy. A total of 127 (93.4%) and 8 (5.9%) participants reported having type 2 and type 1 diabetes, respectively, with a median (IQR) duration of 17 (14) years. The proportion of patients with poor diabetes control (HbA1c ≥ 7%) in the NEDMP was similar to the EDMP (64.0% and 68.2%, respectively; P = 0.411). A significantly higher proportion of patients with DR in the NEDMP were found to have poor diabetes control (HbA1c ≥ 7%) compared to those without DR (80.9% vs. 50.0%, P = 0.003). Almost two-thirds of NEDMP patients (74/118) had DR and 23% (27/115) had diabetic macular edema. The prevalence of DR was similar between the NEDMP and EDMP studies, ranging from 25-30% and 28-29%. The clinical characteristics, diabetes control, and DR severity of English and non-English-speaking patients were similar. The high proportion of poor diabetes management in non-English speaking patients with DR suggests educational and behavioural interventions to improve glycaemic control are warranted. © 2016 Royal Australian and New Zealand College of Ophthalmologists.

Grading diabetic retinopathy (DR using the Scottish grading protocol

Directory of Open Access Journals (Sweden)

Sonia Zachariah

2016-04-01

Full Text Available Although traditionally the features of DR have been identified through direct ophthalmoscopy or slit lamp biomicroscopy, digital photography is more sensitive than direct ophthalmoscopy and is comparable to slit lamp examination by a trained observer.

Stemcell Information: SKIP000139 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

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Stemcell Information: SKIP000137 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available nknown ... Masayo Takahashi 高橋　政代 Riken Center for Developmental Biology (Riken CDB) 理研発生再生科学総合研究センター (理研C...DB) Riken Center for Developmental Biology (Riken CDB) 理研発生再生科学総合研究センター (理研CDB) Masayo Takahashi 高橋　政代 Not A

[Psychoanalysis in Buchenwald. Conversations between Bruno Bettelheim, Dr. Brief and Ernst Federn].

Science.gov (United States)

Federn, E

1988-01-01

Ernst Federn met in the concentration camp Buchenwald Bruno Bettelheim and the Chechoslovakian psychoanalyst Dr. Brief. They discussed the application of psychoanalytic knowledge to the situation in the camp, particularly the defense mechanism of "identification with the aggressor". Of the three, Bettelheim was released after one year, Dr. Brief died in Ausschwitz and Ernst Federn was liberated by the U.S.A. Army. How he could use his psychoanalytic knowledge to survive but also to help fellow prisoners is demonstrated.

The Case of Dr. Oz: Ethics, Evidence, and Does Professional Self-Regulation Work?

Science.gov (United States)

Tilburt, Jon C; Allyse, Megan; Hafferty, Frederic W

2017-02-01

Dr. Mehmet Oz is widely known not just as a successful media personality donning the title "America's Doctor ® ," but, we suggest, also as a physician visibly out of step with his profession. A recent, unsuccessful attempt to censure Dr. Oz raises the issue of whether the medical profession can effectively self-regulate at all. It also raises concern that the medical profession's self-regulation might be selectively activated, perhaps only when the subject of professional censure has achieved a level of public visibility. We argue here that the medical profession must look at itself with a healthy dose of self-doubt about whether it has sufficient knowledge of or handle on the less visible Dr. "Ozes" quietly operating under the profession's presumptive endorsement. © 2017 American Medical Association. All Rights Reserved.

Enterprise Risk Management: The Way Ahead for DRDC within the DND Enterprise

Science.gov (United States)

2010-03-01

Management – Integrated Framework, COSO Executive Summary, Sept 2004 2. Institute of Risk Management (IRM) Risk Management Standard, 2002 3...... Risk Management The Way Ahead for DRDC within the DND Enterprise R.G. Dickinson Dr. B.W. Taylor DRDC CORA Defence R&D Canada – CORA

Dicty_cDB: Contig-U15993-1 [Dicty_cDB

Lifescience Database Archive (English)

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Dr Jacob van der Land, marine biologist extraordinary

NARCIS (Netherlands)

Bruggen, van A.C.

2001-01-01

This contribution is an attempt to sketch the life and works of Dr Jacob van der Land, curator of worms and chief marine biologist of the National Museum of Natural History, on the occasion of his official retirement. Born in 1935, Jacob van der Land read biology at Leiden University (1958-1964),

Dr. Vernon W. Hughes, 81, authority on the subatomic

CERN Multimedia

Lavietes, S

2002-01-01

"Dr. Vernon W. Hughes, a Yale physicist whose investigation of particles called muons poked holes in standard subatomic theory and provided evidence for the existence of previously undetected matter, died at Yale-New Haven Hospital last Tuesday" (1/2 page).

Towards a Theory of Fear Management in the Counter-Terrorism Domain

Directory of Open Access Journals (Sweden)

Edwin Bakker

2014-01-01

Full Text Available Since 9/11, the state of the art in counter-terrorism research, counter-terorism measures and counter-terrorism impacts has taken off. Nevertheless, countering terrorism as a branch of fear management is still a discipline to be developed. In this Research Paper, authors Prof. Dr. Edwin Bakker and Prof. Dr. Beatrice de Graaf attempt to lessen this gap. The Paper identifies and analyses governmental approaches to managing fear in relation to terrorist incidents. It is a stocktaking approach, offering a preliminary oversight of some central aspects and pointers on the way forward when constructing and testing such a theory.

Transcervical Inoculation with Chlamydia trachomatis Induces Infertility in HLA-DR4 Transgenic and Wild-Type Mice.

Science.gov (United States)

Pal, Sukumar; Tifrea, Delia F; Zhong, Guangming; de la Maza, Luis M

2018-01-01

Chlamydia trachomatis is the leading cause of infection-induced infertility in women. Attempts to control this epidemic with screening programs and antibiotic therapy have failed. Currently, a vaccine to prevent C. trachomatis infections is not available. In order to develop an animal model for evaluating vaccine antigens that can be applied to humans, we used C. trachomatis serovar D (strain UW-3/Cx) to induce infertility in mice whose major histocompatibility complex class II antigen was replaced with the human leukocyte antigen DR4 (HLA-DR4). Transcervical inoculation of medroxyprogesterone-treated HLA-DR4 transgenic mice with 5 × 10 5 C. trachomatis D inclusion forming units (IFU) induced a significant reduction in fertility, with a mean number of embryos/mouse of 4.4 ± 1.3 compared to 7.8 ± 0.5 for the uninfected control mice ( P < 0.05). A similar fertility reduction was elicited in the wild-type (WT) C57BL/6 mice (4.3 ± 1.4 embryos/mouse) compared to the levels of the WT controls (9.1 ± 0.4 embryos/mouse) ( P < 0.05). Following infection, WT mice mounted more robust humoral and cellular immune responses than HLA-DR4 mice. As determined by vaginal shedding, HLA-DR4 mice were more susceptible to a transcervical C. trachomatis D infection than WT mice. To assess if HLA-DR4 transgenic and WT mice could be protected by vaccination, 10 4 IFU of C. trachomatis D was delivered intranasally, and mice were challenged transcervically 6 weeks later with 5 × 10 5 IFU of C. trachomatis D. As determined by severity and length of vaginal shedding, WT C57BL/6 and HLA-DR4 mice were significantly protected by vaccination. The advantages and limitations of the HLA-DR4 transgenic mouse model for evaluating human C. trachomatis vaccine antigens are discussed. Copyright © 2017 American Society for Microbiology.

78 FR 9888 - Gulf of Mexico Fishery Management Council; Public Meeting

Science.gov (United States)

2013-02-12

.... SUMMARY: The Gulf of Mexico Fishery Management Council will convene a meeting of the Ad Hoc Artificial... Thursday, February 28, 2013. ADDRESSES: The meeting will be held at the Gulf of Mexico Fishery Management... INFORMATION CONTACT: Dr. John Froeschke, Fishery Biologist- Statistician; Gulf of Mexico Fishery Management...

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Pediatric radiation dose management in digital radiography

International Nuclear Information System (INIS)

Neitzel, U.

2004-01-01

Direct digital radiography (DR) systems based on flat-panel detectors offer improved dose management in pediatric radiography. Integration of X-ray generation and detection in one computer-controlled system provides better control and monitoring

Evaluation of GenoType NTM-DR Assay for Identification of Mycobacterium chimaera.

Science.gov (United States)

Mok, Simone; Rogers, Thomas R; Fitzgibbon, Margaret

2017-06-01

Identification of species within the Mycobacterium avium complex (MAC) is difficult, and most current diagnostic laboratory tests cannot distinguish between species included in the complex. Differentiation of species within the MAC is important, as Mycobacterium chimaera has recently emerged as a major cause of invasive cardiovascular infections following open heart surgery. A new commercial diagnostic assay, GenoType NTM-DR ver. 1.0, is intended to differentiate between three species within the MAC, namely, Mycobacterium avium , Mycobacterium intracellulare , and Mycobacterium chimaera In this study, we investigated an archival collection of 173 MAC isolates using 16S rRNA and 16S-23S internal transcribed spacer (ITS) gene sequencing, and GenoType NTM-DR was evaluated for identifying M. chimaera and other species belonging to the MAC. Species identification of 157/173 (91%) isolates with the GenoType NTM-DR assay was in agreement with 16S rRNA and 16S-23S ITS gene sequencing results. Misidentification occurred with 16 isolates which belonged to four species included in the MAC that are rarely encountered in clinical specimens. Despite some limitations of this assay, GenoType NTM-DR had 100% specificity for identifying M. chimaera This novel assay will enable diagnostic laboratories to differentiate species belonging to the Mycobacterium avium complex and to accurately identify M. chimaera It can produce rapid results and is also more cost efficient than gene sequencing methods. Copyright © 2017 American Society for Microbiology.

Management of groundwater in farmed pond area using risk-based regulation.

Science.gov (United States)

Huang, Jun-Ying; Liao, Chiao-Miao; Lin, Kao-Hung; Lee, Cheng-Haw

2014-09-01

Blackfoot disease (BFD) had occurred seriously in the Yichu, Hsuehchia, Putai, and Peimen townships of Chia-Nan District of Taiwan in the early days. These four townships are the districts of fishpond cultivation domestically in Taiwan. Groundwater becomes the main water supply because of short income in surface water. The problems of over pumping in groundwater may not only result in land subsidence and seawater intrusion but also be harmful to the health of human giving rise to the bioaccumulation via food chain in groundwater with arsenic (As). This research uses sequential indicator simulation (SIS) to characterize the spatial arsenic distribution in groundwater in the four townships. Risk assessment is applied to explore the dilution ratio (DR) of groundwater utilization, which is defined as the ratio showing the volume of groundwater utilization compared to pond water, for fish farming in the range of target cancer risk (TR) especially on the magnitude of 10(-4)~10(-6). Our study results reveal that the 50th percentile of groundwater DRs served as a regulation standard can be used to perform fish farm groundwater management for a TR of 10(-6). For a TR of 5 × 10(-6), we suggest using the 75th percentile of DR for groundwater management. For a TR of 10(-5), we suggest using the 95th percentile of the DR standard for performing groundwater management in fish farm areas. For the TR of exceeding 5 × 10(-5), we do not suggest establishing groundwater management standards under these risk standards. Based on the research results, we suggest that establishing a TR at 10(-5) and using the 95th percentile of DR are best for groundwater management in fish farm areas.

Value Triangles in the Management of Building Projects

DEFF Research Database (Denmark)

Jensen, Per Anker

2013-01-01

The purpose of this paper is to investigate value triangles and their implementation in the management of building projects. The paper is based on results from a research project on space strategies and building values, which included a major case study of the development of facilities for Danish...... Broadcasting Corporation (DR) over time. The conventional iron triangle of quality, cost and schedule for project management is the theoretical starting point, but this is seen as mainly being related to process integrity in the construction stage. It is supplemented by a similar value triangle of cultural...... value, use value and quality of realization for product integrity, mainly for the design stage. Based on this framework an evaluation is made of the value management in six of DR’s building projects from the first around 1930 to the most recent – the new headquarters DR Byen finalised in 2009...

K. Radioactive waste management

International Nuclear Information System (INIS)

1976-01-01

Radioactive waste management is a controversial and emotive subject. This report discusses radioactivity hazards which arise from each stage of the fuel cycle and then relates these hazards to the New Zealand situation. There are three appendices, two of which are detailed considerations of a paper by Dr. B.L.Cohen

Obituary Dr A. W. Kloos (1880—1952)

NARCIS (Netherlands)

Ooststroom, van S.J.

1952-01-01

At the end of the previous number of “Blumea” could just be inserted the death notice of one of the honorary collaborators of the Rijksherbarium, Dr Ir A. W. Kloos, who passed away in his home at Dordrecht on June 3rd, 1952. A more detailed obituary may follow here. Abraham Willem Kloos was born at

Resistensi dan Sensitivitas Bakteri terhadap Antibiotik di RSU dr. Soedarso Pontianak Tahun 2011-2013

OpenAIRE

Nurmala Nurmala; IGN Virgiandhy; Andriani Andriani; Delima F. Liana

2015-01-01

Salah satu upaya untuk mengurangi resistensi, pemberian antibiotik harus berdasarkan pola bakteri penyebab infeksi dan kepekaan bakteri terhadap antibiotik. Tujuan penelitian ini untukmengetahui pola bakteri, resistensi dan sensitivitasnya terhadap antibiotik di RSU dr. SoedarsoPontianak tahun 2011-2013. Penelitian deskriptif dengan pendekatan retrospektif dilakukan RSU dr. Soedarso, Pontianak. Sampel penelitian adalah hasil pemeriksaan kultur dan uji kepekaan spesimen pus pasien yang diperi...

Pressure loss tests for DR-BEP of fullsize 17 x 17 PWR fuel assembly

International Nuclear Information System (INIS)

Chung, Moon Ki; Chun, Se Young; Chang, Seok Kyu; Won, Soon Youn; Cho, Young Rho; Kim, Bok Deuk; Min, Kyoung Ho

1993-01-01

This report describes the conditions, procedure and results in the pressure loss tests carried out for a double grid type debris resistance bottom end piece (DR-BEP) designed by KAERI. In this test, the pressure loss coefficients of the full size 17 x 17 PWR simulated fuel assembly with DR-BET and with standard-BEP were measured respectively, and the pressure loss coefficients of DR-BEP were compared with the coefficients of STD-BET. The test conditions fall within the ranges of loop pressure from 5.2 to 45 bar, loop temperature from 27 to 221 deg C and Reynolds number in fuel bundle from 2.17 x 10 4 to 3.85 x 10 5 . (Author) 5 refs., 18 figs., 5 tabs

Stemcell Information: SKIP000627 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... RIKEN BioResource Center 理化学研究所バイオリソースセンター RIKEN BioResource Center 理化学...研究所バイオリソースセンター Available RIKEN BioResource Center 理化学研究所バイオリソースセンター http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0332&type=1 ...

Grantee Spotlight: Dr. Kolawole Okuyemi - Improving Cervical Cancer Screening Attitudes

Science.gov (United States)

Dr. Kolawole Okuyumi is studying cervical cancer screening attitudes and behaviors of African immigrants and refugees (Ethiopians, Nigerians, and Somalis) in Minnesota, and introducing “cancer” and “cervix” to their everyday vocabulary.

Modelling surface hydrology with DR2-SAGA 1.0: development of a user-friendly interface for hillslope water balance assessments

Science.gov (United States)

López-Montero, Teresa; López-Vicente, Manuel; Navas, Ana

2013-04-01

Soil moisture variability and the depth of water stored in the arable layer of the soil are important topics in agricultural research and rangeland management. Additionally, runoff triggers soil detachment and sediment delivery, and thus is one of the most important factors in the soil erosion dynamic. Overland flow generation and accumulation are non-linear and scale-dependent processes and the development of prediction models helps researchers evaluate different scenarios at different temporal and spatial scales. In this study, we present the DR2-SAGA 1.0 module to the scientific community. The DR2 (Distributed Rainfall-Runoff) water balance model computes the depth of water stored within the soil profile (Waa) distinguishing five scenarios of the upslope contributing area, infiltration processes and climatic parameters, and assesses the soil moisture status (SMS) throughout the year for an average monthly rainfall event. The SAGA program is a free Geographical Information System (GIS) with support for vector and, specially, raster data. Its foundation is its Application Programming Interface (API), which provides data object models and basic definitions for the programming of scientific modules. Module libraries contain the scientific methods and are developed using C++ code. The new module was run in a medium size mountain Mediterranean catchment (246 ha; Spanish Central Pre-Pyrenees) at high spatial resolution (5 x 5 meters of cell size). The Estaña Lakes Catchment is affected by karstic processes which explain the presence of 15 endorheic sub-catchments and three fresh-water lakes. Additionally, this area is ungauged and offers the opportunity to test the performance of the new module in a non-conventional landscape. DR2-SAGA 1.0 demands 16 inputs and generates monthly and annual maps of initial and effective runoff depth, Waa and SMS. One user-friendly tab was created with SAGA 2.0.8 for each input and output file. The new module also includes a water

Stemcell Information: SKIP000134 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available human basic FGF ... Yes Unknown ... Masayo Takahashi 高橋　政代 Riken Center for Developmental Biology... (Riken CDB) 理研発生再生科学総合研究センター (理研CDB) Riken Center for Developmental Biology

Correlation of MMP-9, GA, HbA1c, and adipokines levels with DR

Directory of Open Access Journals (Sweden)

Cheng Qian

2017-12-01

Full Text Available AIM: To investigate the correlation of matrix metalloproteinase -9(MMP-9, glycated albumin(GA, glycosylated hemoglobin(HbA1cand adipokines(including visfatin, resistin and leptinwith diabetic retinopathy(DR. METHODS: From March 2015 to March 2017, 74 patients with DR were treated in our hospital, including 40 patients(80 eyeswith non proliferative diabetic retinopathy(NPDRand 34 patients(68 eyeswith proliferative diabetic retinopathy(PDR, and diabetes mellitus 40 patients(80 eyeswith non DR(NDRand 40 healthy volunteers(80 eyeswere selected as controls, the levels of MMP-9, GA, HbA1c, visfatin, resistin and leptin in each group were detected. RESULTS: PDR group visfatin was 4.41±0.82ng/mL, was significantly lower than the NPDR group, NDR group and control group(PPPPrs=0.523, 0.461 and 0.414, Prs=-0.433, Prs=0.401 and 0.460, PCONCLUSION: MMP-9, GA, HbA1c, and adipokines may play a role in the development and progression of DR, in which MMP-9 is associated with adipokines, both are not significantly related to the levels of GA and HbA1c.

The corpus-driven revolution in Polish Sign Language: the interview with Dr. Paweł Rutkowski

Directory of Open Access Journals (Sweden)

Iztok Kosem

2018-02-01

Full Text Available Dr. Paweł Rutkowski is head of the Section for Sign Linguistics at the University of Warsaw. He is a general linguist and a specialist in the field of syntax of natural languages, carrying out research on Polish Sign Language (polski język migowy — PJM. He has been awarded a number of prizes, grants and scholarships by such institutions as the Foundation for Polish Science, Polish Ministry of Science and Higher Education, National Science Centre, Poland, Polish–U.S. Fulbright Commission, Kosciuszko Foundation and DAAD. Dr. Rutkowski leads the team developing the Corpus of Polish Sign Language and the Corpus-based Dictionary of Polish Sign Language, the first dictionary of this language prepared in compliance with modern lexicographical standards. The dictionary is an open-access publication, available freely at the following address: http://www.slownikpjm.uw.edu.pl/en/. This interview took place at eLex 2017, a biennial conference on electronic lexicography, where Dr. Rutkowski was awarded the Adam Kilgarriff Prize and gave a keynote address entitled Sign language as a challenge to electronic lexicography: The Corpus-based Dictionary of Polish Sign Language and beyond. The interview was conducted by Dr. Victoria Nyst from Leiden University, Faculty of Humanities, and Dr. Iztok Kosem from the University of Ljubljana, Faculty of Arts.

Does transitioning from computed radiography (CR) to direct radiography (DR) with portable imaging systems affect workflow efficiency?

Science.gov (United States)

Gali, Raja L.; Roth, Christopher G.; Smith, Elizabeth; Dave, Jaydev K.

2018-03-01

In digital radiography, computed radiography (CR) technology is based on latent image capture by storage phosphors whereas direct radiography (DR) technology is based either on indirect conversion using a scintillator or direct conversion using a photoconductor. DR-based portable imaging systems may enhance workflow efficiency. The purpose of this work was to investigate changes in workflow efficiency at a tertiary healthcare center after transitioning from CR to DR technology for imaging with portable x-ray units. An IRB exemption was obtained. Data for all inpatient-radiographs acquired with portable x-ray units from July-2014 till June-2015 (period 1) with CR technology (AMX4 or AMX4+ portable unit from GE Healthcare, NX workstation from Agfa Healthcare for digitization), from July-2015 till June-2016 (period 2) with DR technology (Carestream DRX-Revolution x-ray units and DRX-1C image receptors) and from July-2016 till January-2017 (period 3; same DR technology) were extracted using Centricity RIS-IC (GE Healthcare). Duration between the imaging-examination scheduled time and completed time (timesch-com) was calculated and compared using non-parametric tests (between the three time periods with corrections for multiple comparisons; three time periods were used to identify if there were any other potential temporal trends not related to transitioning from CR to DR). IBM's SPSS package was used for statistical analysis. Overall data was obtained from 33131, 32194, and 18015 cases in periods 1, 2 and 3, respectively. Independent-Samples Kruskal-Wallis test revealed a statistically significant difference in timesch-com across the three time periods (χ2(2, n= 83,340) = 2053, p < 0.001). The timesch-com was highest for period 1 i.e., radiographs acquired with CR technology (median: 64 minutes) and it decreased significantly for radiographs acquired with DR technology in periods 2 (median: 49 minutes; p < 0.001) and 3 (median∶ 44 minutes; p < 0.001). Overall

Proceedings of RIKEN BNL Research Center Workshop: P- and CP-odd Effects in Hot and Dense Matter

Energy Technology Data Exchange (ETDEWEB)

Deshpande, A.; Fukushima, K.; Kharzeev, D.; Warringa, H.; Voloshin, S.

2010-04-26

This volume contains the proceedings of the RBRC/CATHIE workshop on 'P- and CP-odd Effects in Hot and Dense Matter' held at the RIKEN-BNL Research Center on April 26-30, 2010. The workshop was triggered by the experimental observation of charge correlations in heavy ion collisions at RHIC, which were predicted to occur due to local parity violation (P- and CP-odd fluctuations) in hot and dense QCD matter. This experimental result excited a significant interest in the broad physics community, inspired a few alternative interpretations, and emphasized the need for a deeper understanding of the role of topology in QCD vacuum and in hot and dense quark-gluon matter. Topological effects in QCD are also closely related to a number of intriguing problems in condensed matter physics, cosmology and astrophysics. We therefore felt that a broad cross-disciplinary discussion of topological P- and CP-odd effects in various kinds of matter was urgently needed. Such a discussion became the subject of the workshop. Specific topics discussed at the workshop include the following: (1) The current experimental results on charge asymmetries at RHIC and the physical interpretations of the data; (2) Quantitative characterization of topological effects in QCD matter including both analytical (perturbative and non-perturbative using gauge/gravity duality) and numerical (lattice-QCD) calculations; (3) Topological effects in cosmology of the Early Universe (including baryogenesis and dark energy); (4) Topological effects in condensed matter physics (including graphene and superfiuids); and (5) Directions for the future experimental studies of P- and CP-odd effects at RHIC and elsewhere. We feel that the talks and intense discussions during the workshop were extremely useful, and resulted in new ideas in both theory and experiment. We hope that the workshop has contributed to the progress in understanding the role of topology in QCD and related fields. We thank all the speakers and

Proceedings of RIKEN BNL Research Center Workshop: P- and CP-odd Effects in Hot and Dense Matter

International Nuclear Information System (INIS)

Deshpande, A.; Fukushima, K.; Kharzeev, D.; Warringa, H.; Voloshin, S.

2010-01-01

This volume contains the proceedings of the RBRC/CATHIE workshop on 'P- and CP-odd Effects in Hot and Dense Matter' held at the RIKEN-BNL Research Center on April 26-30, 2010. The workshop was triggered by the experimental observation of charge correlations in heavy ion collisions at RHIC, which were predicted to occur due to local parity violation (P- and CP-odd fluctuations) in hot and dense QCD matter. This experimental result excited a significant interest in the broad physics community, inspired a few alternative interpretations, and emphasized the need for a deeper understanding of the role of topology in QCD vacuum and in hot and dense quark-gluon matter. Topological effects in QCD are also closely related to a number of intriguing problems in condensed matter physics, cosmology and astrophysics. We therefore felt that a broad cross-disciplinary discussion of topological P- and CP-odd effects in various kinds of matter was urgently needed. Such a discussion became the subject of the workshop. Specific topics discussed at the workshop include the following: (1) The current experimental results on charge asymmetries at RHIC and the physical interpretations of the data; (2) Quantitative characterization of topological effects in QCD matter including both analytical (perturbative and non-perturbative using gauge/gravity duality) and numerical (lattice-QCD) calculations; (3) Topological effects in cosmology of the Early Universe (including baryogenesis and dark energy); (4) Topological effects in condensed matter physics (including graphene and superfiuids); and (5) Directions for the future experimental studies of P- and CP-odd effects at RHIC and elsewhere. We feel that the talks and intense discussions during the workshop were extremely useful, and resulted in new ideas in both theory and experiment. We hope that the workshop has contributed to the progress in understanding the role of topology in QCD and related fields. We thank all the speakers and

A tribute to Dr. Robert C. Allen, an inspirational teacher, humanitarian, and friend (Nov. 18, 1950-Mar. 24, 2005).

Science.gov (United States)

Edlich, Richard F; Greene, Jill A; Long, William B

2006-01-01

Dr. Robert C. Allen was a gifted educator, as well as experienced ophthalmologist, who was a close personal friend of Dr. Edlich at the University of Virginia Health System. While serving on the faculty at the University of Virginia Health System, Dr. Allen proved to be a compassionate physician, who developed close personal relationships with the residents, faculty, and his patients. Dr. Allen was invited by Dr Edlich to be a member of the Editorial Board of the Journal of Long-Term Effects of Medical Implants. When Dr. Allen told Dr. Edlich that he had ocular melanoma in 2000, this news was a wake-up call to Dr. Edlich on the need to prevent skin cancer, as well as ocular melanoma. Empowered by this news, Dr. Edlich was honored to co-author four articles on skin cancer prevention, as well as the latest article focusing on prevention of ocular melanoma. The Ocular Melanoma Foundation (Richmond, VA (USA)) was founded in 2003 by Dr. Robert C. Allen to increase awareness, enhance education, and provide advocacy among both patients and health care professionals regarding this rare, but potentially lethal cancer. It has a website that provides patient information, up-to-date information and enables communication/ discourse between and among patients and practitioners (admin@ocularmelanoma.org). Dr. Allen died on March 24, 2005, at his home surrounded by family and loved ones. When surgeons are faced with challenging healthcare diseases, Dr. Edlich's mentor, Dr. Owen Wangensteen, advised Dr. Edlich that he should seek the advice and guidance of skilled basic scientists, who are familiar with the problem. Dr. Wangensteen is recognized as the greatest surgical teacher during the 20th century. Consequently, Dr. Edlich enlisted the advice and guidance from the two co-authors of the next article regarding the scientific basis for the selection of sunglasses to prevent the development of cataracts, pterygia, skin cancer, as well as ocular melanoma. Dr. Reichow is a Professor

Acceptance of Medical Resume Completion at Dr. Radjiman Wediodiningrat Lawang Psychiatric Hospital

Directory of Open Access Journals (Sweden)

Silvia Shinta Devi

2017-02-01

Sistem kesehatan di Indonesia mengalami perubahan besar dengan diberlakukannya program Asuransi Kesehatan Nasional. Resume medis memiliki peran penting dalam klaim asuransi kesehatan, sehingga resume medis yang terlambat dan tidak lengkap akan mengganggu proses klaim asuransi. Penelitian ini bertujuan untuk mengetahui pengaruh persepsi kemudahan penggunaan, persepsi manfaat, dan sikap pada penerimaan dokter dalam menyelesaikan resume medis. di Dr Radjiman Wedyodiningrat Psychiatric Hospital Lawang berdasarkan Technology Acceptance Model. Technology Acceptance Model digunakan sebagai model dalam penelitian ini karena resume medis merupakan salah satu bentuk teknologi informasi yang masih dilakukan secara manual. Pengumpulan data untuk penelitian ini dilakukan pada bulan Maret 2016 dengan menggunakan kuesioner yang diberikan kepada 32 dokter di Rumah Sakit Jiwa Dr Radjiman Wediodiningrat Lawang. Skala Likert lima tingkat digunakan untuk mengukur setiap item variabel. Data dianalisis dengan menggunakan Partial Least Square. Hasil penelitian menunjukan bahwa secara umum, acceptance dokter di RSJ Dr. Radjiman Wediodiningrat Lawang terhadap pengisian resume medis masuk dalam kategori ringgi dan memiliki perceived usefulness and attitude yang dalam kategori baik, sedangkan perceived ease of use dalam kategori sedang.

MODEL KUANTITATIF MANAJEMEN STRES KERJA DAN MOTIVASI UNTUK MENINGKATKAN KINERJA PETUGAS REKAM MEDIS DI RS ORTOPEDI PROF. DR. R. SOEHARSO SURAKARTA

Directory of Open Access Journals (Sweden)

Laili Rahmatul Ilmi

2016-06-01

Full Text Available Background: Workload may indirectly cause stress. The ability to manage work stress may affect staff’s motivation and performance. The staff performance will affect decision-making in improving the service quality. Objective: This study aimed to analyze the relationship between stress management, work motivation and work performance. Method: This was an analytic observational study with a cross sectional approach. A sample of 19 medical record staff, working at Prof. Dr. R Soeharso orthopedic hospital Surakarta, were selected for this study. A set of questionnaires were developed and administered to measure stress management, work motivation and work performance. Data were then analyzed with a bivariate correlation analysis. Results: There were statistically significant correlations between work stress management, work motivation and work performance. The ability to manage stress positively increased the motivation (r= 0,56; p= 0,013, as well as the work performance (r= 0,49; p= 0,036. Moreover, a higher motivation will lead to a higher performance (r= 0,42; p= 0,071. Conclusion: There were positive relationships between work stress management, work motivation and work performance.

Faktor-Faktor Yang Mempengaruhi Kejadian Insomnia di Poliklinik Saraf RS DR. M. Djamil Padang

OpenAIRE

Lydia Susanti

2015-01-01

Abstrak Faktor risiko seperti usia lanjut, jenis kelamin wanita, penyakit penyerta (depresi dan penyakit lain), status sosial ekonomi rendah menyebabkan insomnia. Penelitian mengenai prevalensi dan faktor-faktor yang mempengaruhi kejadian insomnia di Poliklinik Saraf RS DR. M. Djamil Padang belum pernah dilakukan. Tujuan penelitian ini adalah menentukan faktor-faktor yang mempengaruhi terjadinya insomnia di poliklinik saraf RS DR. M. Djamil Padang. Penelitian ini merupakan penelitian cross se...

A portrait of prefrontal lobotomy performed at the Royal Prince Alfred Hospital in Sydney by Dr Rex Money.

Science.gov (United States)

White, Richard T; McGee-Collett, Martin

2016-10-01

The objective of this article is to provide a portrait of prefrontal lobotomy performed at the Royal Prince Alfred Hospital, Sydney by the Head of Neurosurgery Dr Rex Money and to describe Dr Money's role in the promotion of psychosurgery in Sydney. We draw attention to an oral presentation by Dr Rex Money in 1951, a journal article written by Money, archival information held at the Royal Prince Alfred Hospital, including Dr Money's accounts of his travels and his reports regarding neurosurgery - both internationally and in Australia. Dr Rex Money performed a series of 13 prefrontal lobotomies between 1945 and 1951, and presented the theoretical basis for his series, his operative procedures and the outcomes at the annual meeting of its medical officers' association. Notwithstanding various deficiencies in his clinical research, Money's descriptions give a relatively comprehensive account of one of the first series of prefrontal lobotomies performed in Australia. The current article also describes Dr Money's contributions to the promotion of psychosurgery in Sydney, and illustrates the participation of a senior neurosurgeon and of a major Sydney teaching hospital during the psychosurgery saga. © The Royal Australian and New Zealand College of Psychiatrists 2016.

Show: Dr. H, the life and death of pancakes

CERN Multimedia

2012-01-01

Dr. H, the life and death of pancakes, a comic theatrical creation, written and performed by Heiko Buchholz.   Monday 2 April 2012 in German Tuesday 3 April 2012 in English Wednesday 4 April 2012 in French 8:30 p.m. at the Globe of Science and Innovation. This production takes a comic look at scientific methods, as applied to a common object: the pancake. More specifically, Dr H. regales his audience with statistics, experiments and scientific data surrounding this egg-and-milk-based culinary delight. And although these zany sketches are nothing short of absurd, the audience is drawn in more often than you might expect… and taken on quite an unexpected journey into the behavioural disorders, personality quirks and psychoanalysis of the base pancake. This show playfully mocks scientific logic and discourse, forcing the audience to reflect on their gullibility in the face of science and its impenetrable jargon. It purports to be neither explanation nor illustration of scientific fact,...

Dr. Harry Whelan With the Light Emitting Diode Probe

Science.gov (United States)

1999-01-01

The red light from the Light Emitting Diode (LED) probe shines through the fingers of Dr. Harry Whelan, a pediatric neurologist at the Children's Hospital of Wisconsin in Milwaukee. Dr. Whelan uses the long waves of light from the LED surgical probe to activate special drugs that kill brain tumors. Laser light previously has been used for this type of surgery, but the LED light illuminates through all nearby tissues, reaching parts of tumors that shorter wavelengths of laser light carnot. The new probe is safer because the longer wavelengths of light are cooler than the shorter wavelengths of laser light, making the LED less likely to injure normal brain tissue near the tumor. Also, it can be used for hours at a time while still remaining cool to the touch. The probe was developed for photodynamic cancer therapy under a NASA Small Business Innovative Research Program grant. The program is part of NASA's Technology Transfer Department at the Marshall Space Flight Center.

[United Nations world population prize to Dr. Halfdan Mahler. Acceptance speech].

Science.gov (United States)

Mahler, H

1995-06-01

The professional achievements of Halfdan Mahler, for which he was awarded the 1995 UN World Population Prize, are summarized, and Dr. Mahler's acceptance speech is presented. Dr. Mahler worked for reproductive health and sustainable development during his six years as secretary general of the IPPF. Under his leadership, the IPPF established world standards for family planning and reproductive health. Dr. Mahler also guided creation and implementation of the long-term IPPF strategic plan, Vision 2000. During his tenure as director general of the World Health Organization from 1973 to 1988, he established the special program of education, development, and training for research in human reproduction. Dr. Mahler's acceptance speech sketched a world of the future in which women control their reproductive lives and enjoy equality with men in work and at home, where adolescents understand and control their sexuality, where all children are desired and cared for, and where hard work brings success even in the poorest population sectors. The challenges of achieving this vision are enormous. The world's population will have doubled to 10 billion, and tensions and inequities will persist. But if the vision is not fulfilled, the present population will triple to 15 billion and competition for every kind of resource will be intolerable. In order to succeed, the rights to free and informed reproductive decision making must be guaranteed for every couple. Harmful practices that violate the right to autonomous reproductive decision making, such as early marriage or female genital mutilation, must be eliminated. Governments must commit themselves to educating and providing resources to women so that they can exercise their rights. Family planning services must be extended to the poor and marginal population sectors that still are denied access, and to adolescents who are at risk of unwanted pregnancy and disease.

Stemcell Information: SKIP000827 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... RIKEN BioResource Center 理化学研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Ava...ilable RIKEN BioResource Center 理化学研究所バイオリソースセンター http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0332&type=1 ...

Stemcell Information: SKIP000633 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... Yes ... RIKEN BioResource Center 理化学研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター ... Avai...lable RIKEN BioResource Center 理化学研究所バイオリソースセンター http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0337&type=1 ...

Stemcell Information: SKIP000632 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... Yes ... RIKEN BioResource Center 理化学研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター ... Avai...lable RIKEN BioResource Center 理化学研究所バイオリソースセンター http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0337&type=1 ...

Stemcell Information: SKIP000614 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available a patient.Amyotrophic lateral sclerosis, Familial type. ... 疾患特異的iPS細胞株。家族性筋萎縮性側索硬化症患者由来。 human ES-like Resear...sclerosis, Familial type ... -- -- Japanese Japanese No No Disease specific iPS cell line derived from...g/ml human bFGF ... 3% Unknown ... RIKEN BRC 理研BRC RIKEN BRC 理研BRC ... Available RIKEN BRC 理研BRC http://www.brc.riken.jp/lab/cell/english/ ...

Stemcell Information: SKIP000634 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... Yes ... RIKEN BioResource Center 理化学研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター ... Avai...lable RIKEN BioResource Center 理化学研究所バイオリソースセンター http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0337&type=1 ...

BDML Metadata: 52 [SSBD[Archive

Lifescience Database Archive (English)

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Lifescience Database Archive (English)

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BDML Metadata: 210 [SSBD[Archive

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Human radiation studies: Remembering the early years. Oral history of Dr. George Voelz, M.D., November 29, 1994

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-05-01

Dr. George Voelz was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). This oral history covers Dr. Voelz`s research on Manhattan Engineering District plutonium workers, the acute and long term effects of radiation, his inhalation studies, and his activities at the 1961 INL reactor accident (SL-1 Reactor). After a brief biographical sketch, Dr. Voelz his remembrances on tissue studies of plutonium workers, the plutonium injection studies of 1945-1946, the controlled environmental radioiodine tests of 1963-1968, and tracer studies with human volunteers at Los Alamos. Dr. Voelz states his opinions concerning misconceptions about the Los Alamos Human Radiation Experiments.

Human radiation studies: Remembering the early years. Oral history of Dr. George Voelz, M.D., November 29, 1994

International Nuclear Information System (INIS)

1995-05-01

Dr. George Voelz was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). This oral history covers Dr. Voelz's research on Manhattan Engineering District plutonium workers, the acute and long term effects of radiation, his inhalation studies, and his activities at the 1961 INL reactor accident (SL-1 Reactor). After a brief biographical sketch, Dr. Voelz his remembrances on tissue studies of plutonium workers, the plutonium injection studies of 1945-1946, the controlled environmental radioiodine tests of 1963-1968, and tracer studies with human volunteers at Los Alamos. Dr. Voelz states his opinions concerning misconceptions about the Los Alamos Human Radiation Experiments

Demand-side management and demand response in the Ontario energy sectors

International Nuclear Information System (INIS)

2004-01-01

A directive from the former Minister of Energy was received by the Ontario Energy Board (OEB), directing the Board to consult with stakeholders on options for the delivery of demand-side management (DSM) and demand response (DR) activities within the electricity sector, including the role of local distribution companies in such activities. The implementation costs were to be balanced with the benefits to both consumers and the entire system. The scope of the review was expanded by the Board to include the role of gas distribution companies in DSM. A consultation process was implemented and stakeholders were invited to participate. A series of recommendations was made, including: (1) a hybrid framework utilizing market-based and public-policy approaches should deliver DSM and DR activities in Ontario's energy markets, (2) DSM and DR activities should come under the responsibility of a central agency, (3) DSM and DR activities should be coordinated through cooperation between the Ministry of Energy, the Independent Electricity Market Operator (IMO) and the Ontario Energy Board, (4) regulatory mechanisms to induce gas distributors, electricity transmitters and electricity distributors to reduce distribution system losses should be put in place, (5) all electricity consumers should fund electricity DSM and some retail DR initiatives through a transparent, non-bypassable consumption charge, and (6) the Board should design, develop and deliver information to consumers regarding energy conservation, energy efficiency, load management, and cleaner sources of energy. refs., 4 figs

Uzm Dr Sebahattin Okumuş 05-09-1937 - 14-03-2003

Directory of Open Access Journals (Sweden)

Veli Özdemir

2003-12-01

Full Text Available 1993 yılının Temmuz ayında tanıştık. Otopsisi ertesi güne kalan bir cenazenin başında beklerken, Fatih Adli Tabibi olduğunu anladığım iriyarı ve göbekli bir kişi kendine has yürüyüşüyle cenaze başına geldi. Daha tanışamadan elindeki dörde katlanmış ve “A4” olduğu belli olan kağıda hızlı bir biçimde not almaya başladı. Çevresiyle bağını koparmış, dış muayeneye ve elindeki kağıda konsantre olmuştu; birşey soranları “dur şimdi zamanı değil!” biçiminde geri çeviriyordu. Bu cümlenin, kendisinin her zaman kullandığı bir deyim olduğunu tanıyanlar bilir. Sonunda muayene bitti ve tanıştık; Dr. Sebahattin Okumuş imiş. “Sebahattin” olan adının “Sabahattin” olarak telaffuz edilmesine ve yazılmasına çok kızardı. Bunu ilk tanıştığımız gün anladım. Daha soma kendisiyle sık sık görüşmemizin dışmda, 1998-1999 yıllarında Fatih Adli Tabipliğinde çok yakından tanımamı sağlayacak 1 yıl kadar birlikte çalıştık... Kendi sağlığına pek dikkat etmez ve hele KOAH'lı (Kronik Obstrüktif Akciğer Hastahğı olmasına karşın ilaçlarım düzenli almaz ve bir hekim olmasına karşın doktor korkusundan dolayı kontrole gitmekten çekinirdi. Hastalığmın alevlendiği dönemlerde, ölü muayenesi için 1 kat merdiven çıkmak zorunda kalacağı için Cerrahpaşa Tıp Fakültesi'nin morguna gitmek istemezdi. 1999 yılı itibariyle 15 yıllık KOAH'lı olması ve tam konulduğu gün 20 yıh aşkın süre boyunca günde 2-3 paket kullandığı sigarayı birden bırakması (zorunda kalması dışında sağhğma pek dikkat etmemesi bildiğim en kötü yanıydı... Evine sürekli bir şeyler taşıması, oğlunun üzerine titremesi, eşi ve oğlu ile telefondaki diyaloglarından kendisinin evine pek düşkün olduğu, iyi bir “aile babası” ve “aile reisi” olduğu anlaşılıyordu. Evi ve işi dışında zaman geçirdiği tek yer Cengiz Ağabeyin (Uz

VizieR Online Data Catalog: Mira stars discovered in LAMOST DR4 (Yao+, 2017)

Science.gov (United States)

Yao, Y.; Liu, C.; Deng, L.; de Grijs, R.; Matsunaga, N.

2017-10-01

By the end of 2016 March, the wide-field Large sky Area Multi-Object fiber Spectroscopic Telescope (LAMOST) DR4 catalog had accumulated 7681185 spectra (R=1800), of which 6898298 were of stars. We compiled a photometrically confirmed sample of Mira variables from the Kiso Wide-Field Camera (KWFC) Intensive Survey of the Galactic Plane (KISOGP; Matsunaga 2017, arXiv:1705.08567), the American Association of Variable Star Observers (AAVSO) International Database Variable Star Index (VSX; Watson 2006, B/vsx, version 2017-05-02; we selected stars of variability type "M"), and the SIMBAD Astronomical Database. We first cross-matched the KISOGP and VSX Miras with the LAMOST DR4 catalog. Finally, we cross-matched the DR4 catalog with the SIMBAD database. See section 2. (1 data file).

VizieR Online Data Catalog: Gaia DR2 (Gaia Collaboration, 2018)

Science.gov (United States)

Gaia Collaboration

2018-04-01

Contents of Gaia DR2: The five-parameter astrometric solution - positions on the sky (alpha,delta), parallaxes, and proper motions - for more than 1.3 billion (109) sources, with a limiting magnitude of G=21 and a bright limit of G~=3. Parallax uncertainties are in the range of up to 0.04 milliarcsecond for sources at G2MASS PSC, SDSS DR9, Pan-STARRS1, GSC2.3, PPM-XL, AllWISE, and URAT-1 data on the other hand. Catalogue of radial velocity standard stars (Soubiran et al., 2018A&A..in.prep...): Individual and combined radial velocity measurements are presented for 4813 stars in rvstdcat.dat and rvstdmes.dat files. (20 data files).

Puma and Trail/Dr5 Pathways Control Radiation-Induced Apoptosis in Distinct Populations of Testicular Progenitors

International Nuclear Information System (INIS)

Coureuil, M.; Tavernier, M.; Barroca, V.; Fouchet, P.; Allemand, I.; Ugolin, N.; Chevillard, S.

2010-01-01

Spermatogonia- stem cells and progenitors of adult spermatogenesis- are killed through a p53-regulated apoptotic process after γ-irradiation but the death effectors are still poorly characterized. Our data demonstrate that both intrinsic and extrinsic apoptotic pathways are involved, and especially that spermatogonia can be split into two main populations, according to apoptotic effectors. Following irradiation both Dr5 and Puma genes are up-regulated in the α 6 -integrin-positive Side Population (SP) fraction, which is highly enriched in spermatogonia. Flow cytometric analysis confirms an increased number of Dr5-expressing SP cells, and Puma-β isoform accumulates in α 6 -integrin positive cellular extracts, enriched in spermatogonia. Trail -/- or Puma -/- spermatogonia display a reduced sensitivity to radiation-induced apoptosis. The TUNEL kinetics strongly suggest that the extrinsic and intrinsic pathways, via Trail/Dr5 and Puma respectively, could be engaged in distinct subpopulations of spermatogonia. Indeed flow cytometric studies show that Dr5 receptor is constitutively present on more than half of the undifferentiated progenitors (Kit - α 6 + SP) and half of the differentiated ones (Kit + α 6 + SP). In addition after irradiation, Puma is not detected in the Dr5-positive cellular fraction isolated by immuno-magnetic purification, while Puma is present in the Dr5-negative cell extracts. In conclusion, adult testicular progenitors are divided into distinct sub-populations by apoptotic effectors, independently of progenitor types (immature Kit-negative versus mature Kit-positive), underscoring differential radiosensitivities characterizing the stem cell/progenitors compartment. (authors)

Rembrandt's anatomy lesson of Dr. Deijman of 1656 dissected

NARCIS (Netherlands)

Ijpma, Frank F. A.; Middelkoop, Norbert E.; van Gulik, Thomas M.

2013-01-01

More than 350 years ago, Rembrandt painted Anatomy Lesson of Dr. Deijman. This group portrait, featuring important members of the Amsterdam Guild of Surgeons, belongs to the series of paintings of the guild. Rembrandt's masterpiece is one of the most famous historical images of a dissection of the

Lack of death receptor 4 (DR4) expression through gene promoter methylation in gastric carcinoma.

Science.gov (United States)

Lee, Kyung Hwa; Lim, Sang Woo; Kim, Ho Gun; Kim, Dong Yi; Ryu, Seong Yeob; Joo, Jae Kyun; Kim, Jung Chul; Lee, Jae Hyuk

2009-07-01

To determine the underlying mechanism for the differential expression, the extent of promoter methylation in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-related genes acting downstream of TRAIL was examined in early and advanced gastric carcinomas. The extent of promoter methylation in the DR4, DR5, DcR1, DcR2, and CASP8 genes was quantified using bisulfite modification and methylation-specific polymerase chain reaction. The promoters for DcR1, DcR2, and CASP8 were largely unmethylated in early gastric carcinoma, advanced gastric carcinoma, and controls, with no significant difference among them. Protein levels of DR4, DcR1, and DcR2 as revealed by immunohistochemistry correlated with the extent of the respective promoter methylation (P < 0.05 in all cases). Hypomethylation, rather than hypermethylation, of the DR4 promoter was noted in invasive gastric malignancies, with statistical significance (P = 0.003). The promoter methylation status of TRAIL receptors in gastric carcinoma may have clinical implications for improving therapeutic strategies in patients with gastric carcinoma.

Intra HLA-D/DR region recombinant detected by primed lymphocyte typing (PLT)

DEFF Research Database (Denmark)

Jakobsen, B K; Kristensen, T; Lamm, L U

1983-01-01

The chromosome 6 markers, HLA-ABC, D, DR, MT, properdin factor Bf, and complement factors 2 (C2) and 5 (C4), were studied in three families, each of which included two HLA identical siblings, one or both of whom were known to be HLA-B: GLO recombinants. The families were also typed with primed...... lymphocyte typing (PLT) for HLA-D/DR region associated DP antigens. None of these studies gave evidence that the recombinations had occurred within the HLA region. Mixed leucocyte culture (MLC) tests within the families showed no detectable stimulation between the HLA identical siblings in two...

Stemcell Information: SKIP000136 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available iology (Riken CDB) 理研発生再生科学総合研究センター (理研CDB) Masayo Takahashi 高橋　政代 Not Available Riken BRC 理研BRC http://www.brc.riken.jp/lab/cell/english/patient_specific_ips.shtml ...

Stemcell Information: SKIP000135 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available iology (Riken CDB) 理研発生再生科学総合研究センター (理研CDB) Masayo Takahashi 高橋　政代 Not Available Riken BRC 理研BRC http://www.brc.riken.jp/lab/cell/english/patient_specific_ips.shtml ...

MANAGEMENT BOARD MEETING OF 1st JULY 2002

CERN Multimedia

2002-01-01

Composition of the new Staff Association Executive Committee The Management Board took note of the composition of the new Staff Association Executive Committee and congratulated Dr J.-P. Matheys on his re-election as President and Dr M. Goossens and Mr M. Vitasse on their election as Vice-Presidents. Outcome of the June Council week The Director-General presented the main results of the meetings of the Council and its committees during the week of 17-21 June. He reported that, following discussion of the final report by the External Review Committee at the various committees, the Council had accepted the ERC's recommendations on the LHC Project and the management of the Organization, expressing the view that the report and the Management's proposals constituted an important step towards resolving the problems identified since the emergence of the LHC funding shortfall in the second half of 2001 and re-establishing an atmosphere of trust. The extra costs for the LHC Project would be covered by a balanced packa...

Autocrine secretion of tumor necrosis factor under the influence of interferon-γ amplifies HLA-DR gene induction in human monocytes

International Nuclear Information System (INIS)

Arenzana-Seisdedos, F.; Mogensen, S.C.; Vuillier, F.; Fiers, W.; Virelizier, J.L.

1988-01-01

Recombinant interferon-γ (IFN-γ) induced HLA-DR gene expression in both U937 and THP-1 human monocytic cell lines, although the former was only very weakly inducible. Combination of recombinant tumor necrosis factor (TNF) and IFN-γ resulted in a synergistic enhancement of DR mRNA and protein induction in both cell lines. TNF alone increased the constitutive expression of the DR gene in THP-1 cells. In the HLA class II-negative U937 cells, TNF used alone was not able to induce DR gene expression. Such a negative result was not due to a lack of TNF receptor expression in U937 cells, since TNF clearly induced HLA class I and TNF gene expression in this cell line. THP-1, but not U937, cells secreted TNF under the influence of IFN-γ. Neutralization of TNF by a specific antibody decreased IFN-γ-induced DR antigen expression in THP-1 cultures. These observations indicate that TNF is not able to directly induce DR gene expression, but rather amplifies ongoing expression of this gene, whether constitutive or induced by IFN-γ. In the two cell lines tested, the level of DR inducibility under the influence of IFN-γ used alone depended on a different inducibility of TNF secretion by IFN-γ. Altogether, the observations indicate that TNF, whether exogenous or endogenously produced under the influence of IFN-γ, amplifies DR gene expression in monocytes, a phenomenon that may provide to such antigen-presenting cells a selective sensitivity to the DR-inducing effects of IFN-γ

The influence of Dr. Hsiang-Tung Chang on neuroscience in Union of Soviet Socialist Republics.

Science.gov (United States)

Jiang, Chun

2012-10-25

As one of the founders of Chinese neuroscience, Dr. Hsiang-Tung Chang's return to China has a profound impact on neuroscience in China. As many people expected, this action also may have influenced the development of neuroscience in other Eastern countries. Therefore, Dr. Chang's move may have changed the history of neuroscience in a greater area than China.

Impact of water quality and irrigation management on soil salinization in the Drâa valley of Morocco.

Science.gov (United States)

Beff, L.; Descamps, C.; Dufey, J.; Bielders, C.

2009-04-01

Under the arid climatic conditions of the Drâa valley in southern Morocco, irrigation is essential for crop production. Two sources of water are available to farmers: (1) moderate salinity water from the Oued Drâa (classified as C3-S1 in the USDA irrigation water classification diagram) which is available only a few times per year following discrete releases from the Mansour Eddahbi dam, and (2) high salinity water from wells (C4-S2). Soil salinization is frequently observed, principally on plots irrigated with well water. As Oued water is available in insufficient amounts, strategies must be devised to use well and Oued water judiciously, without inducing severe salinization. The salinization risk under wheat production was evaluated using the HP1 program (Jacques and Šimůnek, 2005) for different combinations of the two main water sources, different irrigation frequencies and irrigation volumes. The soil was a sandy clay loam (topsoil) to sandy loam (40 cm depth). Soil hydrodynamic properties were derived from in situ measurements and lab measurements on undisturbed soil samples. The HP1 model was parameterized for wheat growth and 12 scenarios were run for 10 year periods using local climatic data. Water quality was measured or estimated on the basis of water samples in wells and various Oueds, and the soil chemical properties were determined. Depending on the scenario, soil salinity in the mean root zone increased from less than 1 meq/100g of soil to more than 5 meq/100g of soil over a ten year period. Salt accumulation was more pronounced at 45 cm soil depth, which is half of the maximum rooting depth, and when well water was preferentially used. Maximum crop yield (water transpired / potential water transpired) was achieved for five scenarios but this implied the use of well water to satisfy the crop water requirements. The usual Drâa Valley irrigation scenario, with five, 84 mm dam water applications per year, lead to a 25% yield loss. Adding the amount

Levels of Organisation in agent-based modelling for renewable resources management. Agricultural water management collective rules enforcement in the French Drome River Valley Case Study

International Nuclear Information System (INIS)

Abrami, G.

2004-11-01

Levels of Organisation in agent-based modelling for renewable resources management. Agricultural water management collective rules enforcement in the French Dr me River Valley Case Study. In the context of Agent-Based Modelling for participative renewable resources management, this thesis is concerned with representing multiple tangled levels of organisation of a system. The Agent-Group-Role (AGR) formalism is borrowed from computer science research. It has been conceptually specified to handle levels of organisation, and behaviours within levels of organisation. A design methodology dedicated to AGR modelling has been developed, together with an implementation of the formalism over a multi-agent platform. AGR models of agricultural water management in the French Dr me River Valley have been built and tested. This experiment demonstrates the AGR formalism ability to (1) clarify usually implicit hypothesis on action modes, scales or viewpoints (2) facilitate the definition of scenarios with various collective rules, and various rules in enforcement behaviours (3) generate bricks for generic irrigated catchment models. (author)

Predominant antitumor effects by fully human anti-TRAIL-receptor2 (DR5) monoclonal antibodies in human glioma cells in vitro and in vivo

Science.gov (United States)

Nagane, Motoo; Shimizu, Saki; Mori, Eiji; Kataoka, Shiro; Shiokawa, Yoshiaki

2010-01-01

Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL/Apo2 L) preferentially induces apoptosis in human tumor cells through its cognate death receptors DR4 or DR5, thereby being investigated as a potential agent for cancer therapy. Here, we applied fully human anti-human TRAIL receptor monoclonal antibodies (mAbs) to specifically target one of death receptors for TRAIL in human glioma cells, which could also reduce potential TRAIL-induced toxicity in humans. Twelve human glioma cell lines treated with several fully human anti-human TRAIL receptor mAbs were sensitive to only anti-DR5 mAbs, whereas they were totally insensitive to anti-DR4 mAb. Treatment with anti-DR5 mAbs exerted rapid cytotoxicity and lead to apoptosis induction. The cellular sensitivity was closely associated with cell-surface expression of DR5. Expression of c-FLIPL, Akt, and Cyclin D1 significantly correlated with sensitivity to anti-DR5 mAbs. Primary cultures of glioma cells were also relatively resistant to anti-DR5 mAbs, exhibiting both lower DR5 and higher c-FLIPL expression. Downregulation of c-FLIPL expression resulted in the sensitization of human glioma cells to anti-DR5 mAbs, whereas overexpression of c-FLIPL conferred resistance to anti-DR5 mAb. Treatment of tumor-burden nude mice with the direct agonist anti-DR5 mAb KMTR2 significantly suppressed growth of subcutaneous glioma xenografts leading to complete regression. Similarly, treatment of nude mice bearing intracerebral glioma xenografts with KMTR2 significantly elongated lifespan without tumor recurrence. These results suggest that DR5 is the predominant TRAIL receptor mediating apoptotic signals in human glioma cells, and sensitivity to anti-DR5 mAbs was determined at least in part by the expression level of c-FLIPL and Akt. Specific targeting of death receptor pathway through DR5 using fully human mAbs might provide a novel therapeutic strategy for intractable malignant gliomas. PMID:20511188

Regulation of MntH by a dual Mn(II- and Fe(II-dependent transcriptional repressor (DR2539 in Deinococcus radiodurans.

Directory of Open Access Journals (Sweden)

Hongxing Sun

Full Text Available The high intracellular Mn/Fe ratio observed within the bacteria Deinococcus radiodurans may contribute to its remarkable resistance to environmental stresses. We isolated DR2539, a novel regulator of intracellular Mn/Fe homeostasis in D. radiodurans. Electrophoretic gel mobility shift assays (EMSAs revealed that DR2539 binds specifically to the promoter of the manganese acquisition transporter (MntH gene, and that DR0865, the only Fur homologue in D. radiodurans, cannot bind to the promoter of mntH, but it can bind to the promoter of another manganese acquisition transporter, MntABC. β-galactosidase expression analysis indicated that DR2539 acts as a manganese- and iron-dependent transcriptional repressor. Further sequence alignment analysis revealed that DR2539 has evolved some special characteristics. Site-directed mutagenesis suggested that His98 plays an important role in the activities of DR2539, and further protein-DNA binding activity assays showed that the activity of H98Y mutants decreased dramatically relative to wild type DR2539. Our study suggests that D. radiodurans has evolved a very efficient manganese regulation mechanism that involves its high intracellular Mn/Fe ratio and permits resistance to extreme conditions.

Stemcell Information: SKIP000624 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available RIKEN BioResource Center 理化学研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Available RIKEN BioResource Center 理化学

Mannose-binding lectin variant alleles and HLA-DR4 alleles are associated with giant cell arteritis

DEFF Research Database (Denmark)

Jacobsen, Soren; Baslund, Bo; Madsen, Hans O.

2002-01-01

/GCA, MBL variant alleles were associated with signs of increased inflammatory activity and clinical signs of arteritic manifestations. This was not found for HLA-DR4 alleles. These findings indicate that HLA-DR4 and MBL are contributing to the pathophysiology of GCA at different levels in the disease...... alleles in controls, patients with PMR only, and patients with GCA was 37, 32, and 53% (p = 0.01), respectively. HLA-DRB1*04 was found in 47% of patients with PMR only and in 54% of patients with GCA, which differed significantly from the 35% found in controls (p = 0.01). HLA-DR4 alleles were...... not associated with any clinical phenotypes of PMR/GCA, whereas MBL variant alleles were associated with cranial arteritis, high erythrocyte sedimentation rate, and low B-hemoglobin. CONCLUSION: We found MBL variant alleles and HLA-DR4 alleles to be weak susceptibility markers for GCA. In patients with PMR...

GENESI-DR Portal: a scientific gateway to distributed repositories

Science.gov (United States)

Goncalves, Pedro; Brito, Fabrice; D'Andria, Fabio; Cossu, Roberto; Fusco, Luigi

2010-05-01

GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories) is a European Commission (EC)-funded project, kicked-off early 2008 lead by ESA; partners include Space Agencies (DLR, ASI, CNES), both space and no-space data providers such as ENEA (I), Infoterra (UK), K-SAT (N), NILU (N), JRC (EU) and industry as Elsag Datamat (I), CS (F) and TERRADUE (I). GENESI-DR intends to meet the challenge of facilitating "time to science" from different Earth Science disciplines in discovery, access and use (combining, integrating, processing, …) of historical and recent Earth-related data from space, airborne and in-situ sensors, which are archived in large distributed repositories. "Discovering" which data are available on a "geospatial web" is one of the main challenges ES scientists have to face today. Some well- known data sets are referred to in many places, available from many sources. For core information with a common purpose many copies are distributed, e.g., VMap0, Landsat, and SRTM. Other data sets in low or local demand may only be found in a few places and niche communities. Relevant services, results of analysis, applications and tools are accessible in a very scattered and uncoordinated way, often through individual initiatives from Earth Observation mission operators, scientific institutes dealing with ground measurements, service companies or data catalogues. In the discourse of Spatial Data Infrastructures, there are "catalogue services" - directories containing information on where spatial data and services can be found. For metadata "records" describing spatial data and services, there are "registries". The Geospatial industry coins specifications for search interfaces, where it might do better to reach out to other information retrieval and Internet communities. These considerations are the basis for the GENESI-DR scientific portal, which adopts a simple model allowing the geo-spatial classification and discovery of

Multifunctional PMMA@Fe3O4@DR Magnetic Materials for Efficient Adsorption of Dyes

Directory of Open Access Journals (Sweden)

Bing Yu

2017-10-01

Full Text Available Magnetic porous microspheres are widely used in modern wastewater treatment technology due to their simple and quick dye adsorption and separation functions. In this article, we prepared porous polymethylmethacrylate (PMMA microspheres by the seed-swelling method, followed by in situ formation of iron oxide (Fe3O4 nanoparticles within the pore. Then, we used diazo-resin (DR to encapsulate the porous magnetic microspheres and achieve PMMA@Fe3O4@DR magnetic material. We studied the different properties of magnetic microspheres by different dye adsorption experiments before and after the encapsulation and demonstrated that the PMMA@Fe3O4@DR microspheres can be successfully used as a reusable absorbent for fast and easy removal of anionic and aromatic dyes from wastewater and can maintain excellent magnetic and adsorption properties in harsh environments.

Total Quality Management Analysis of LAMPS MK 1 Aviation Maintenance Data

Science.gov (United States)

1992-06-05

Qualit Control? The Japanese Way by Dr. Kaoru Ishikawa translated by David J. Lu offers the Japanese version of Total Quality Management. Dr...causes to an effect or problem. It is called the Ishikawa Diagram after its inventor Kaoru Ishikawa , a pioneer in quality control. The name fishbone...pathways involved. 2) Cause and Effect Diagram (also known as an Ishikawa Diagram or a Fishbone Diagram). This diagram used to identify the causes, and

Stemcell Information: SKIP000807 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available tia of Alzheimers type. Order Form to RIKEN BRC (C-0042, C-0057, C-0007). 疾患特異的iPS細胞株。アルツハイマー型認知症患者由来。ガラス化法(...ers type - ... -- Male Japanese 日本人 No No Disease specific iPS cell line derived from a patient : Demen...enter (RIKEN ... BRC 理化学研究所バイオリソースセンター Available RIKEN BioResouce Center (RIKEN ... BRC) 理化学研究所バイオリソースセンター http://www2.brc.riken.jp/lab/cel...l/detail.cgi?cell_no=HPS0059&type=1 ...

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Dr. von Braun With a Model of a Launch Vehicle

Science.gov (United States)

1950-01-01

Dr. von Braun stands beside a model of the upper stage (Earth-returnable stage) of the three-stage launch vehicle built for the series of the motion picture productions of space flight produced by Walt Disney in the mid-1950's.

Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy.

Science.gov (United States)

Wang, Junjian; Wang, Haibin; Wang, Ling-Yu; Cai, Demin; Duan, Zhijian; Zhang, Yanhong; Chen, Peng; Zou, June X; Xu, Jianzhen; Chen, Xinbin; Kung, Hsing-Jien; Chen, Hong-Wu

2016-11-01

Recombinant TRAIL and agonistic antibodies to death receptors (DRs) have been in clinical trial but displayed limited anti-cancer efficacy. Lack of functional DR expression in tumors is a major limiting factor. We report here that chromatin regulator KDM4A/JMJD2A, not KDM4B, has a pivotal role in silencing tumor cell expression of both TRAIL and its receptor DR5. In TRAIL-sensitive and -resistant cancer cells of lung, breast and prostate, KDM4A small-molecule inhibitor compound-4 (C-4) or gene silencing strongly induces TRAIL and DR5 expression, and causes TRAIL-dependent apoptotic cell death. KDM4A inhibition also strongly sensitizes cells to TRAIL. C-4 alone potently inhibits tumor growth with marked induction of TRAIL and DR5 expression in the treated tumors and effectively sensitizes them to the newly developed TRAIL-inducer ONC201. Mechanistically, C-4 does not appear to act through the Akt-ERK-FOXO3a pathway. Instead, it switches histone modifying enzyme complexes at promoters of TRAIL and DR5 transcriptional activator CHOP gene by dissociating KDM4A and nuclear receptor corepressor (NCoR)-HDAC complex and inducing the recruitment of histone acetylase CBP. Thus, our results reveal KDM4A as a key epigenetic silencer of TRAIL and DR5 in tumors and establish inhibitors of KDM4A as a novel strategy for effectively sensitizing tumors to TRAIL pathway-based therapeutics.

Post-Disaster Image Processing for Damage Analysis Using GENESI-DR, WPS and Grid Computing

OpenAIRE

Bielski, Conrad; Gentilini, Simone; Pappalardo, Marco

2011-01-01

The goal of the two year Ground European Network for Earth Science Interoperations-Digital Repositories (GENESI-DR) project was to build an open and seamless access service to Earth science digital repositories for European and world-wide science users. In order to showcase GENESI-DR, one of the developed technology demonstrators focused on fast search, discovery, and access to remotely sensed imagery in the context of post-disaster building damage assessment. This paper descri...