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Sample records for revealed varying degrees

  1. The Production of Emotional Prosody in Varying Degrees of Severity of Apraxia of Speech.

    Science.gov (United States)

    Van Putten, Steffany M.; Walker, Judy P.

    2003-01-01

    A study examined the abilities of three adults with varying degrees of apraxia of speech (AOS) to produce emotional prosody. Acoustic analyses of the subjects' productions revealed that unlike the control subject, the subjects with AOS did not produce differences in duration and amplitude cues to convey different emotions. (Contains references.)…

  2. Aquatic macrophyte community varies in urban reservoirs with different degrees of eutrophication

    Directory of Open Access Journals (Sweden)

    Suelen Cristina Alves da Silva

    2014-06-01

    Full Text Available AIM: Investigate spatial and temporal variation in the aquatic macrophyte community in four urban reservoirs located in Curitiba metropolitan region, Brazil. We tested the hypothesis that aquatic macrophyte community differ among reservoirs with different degrees of eutrophication. METHODS: The reservoirs selected ranged from oligotrophic/mesotrophic to eutrophic. Sampling occurred in October 2011, January 2012 and June 2012. Twelve aquatic macrophytes stands were sampled at each reservoir. Species were identified and the relative abundance of aquatic macrophytes was estimated. Differences among reservoirs and over sampling periods were analyzed: i through two‑way ANOVAs considering the stand extent (m and the stand biodiversity - species richness, evenness, Shannon-Wiener index and beta diversity (species variation along the aquatic macrophyte stand; and ii through PERMANOVA considering species composition. Indicator species that were characteristic for each reservoir were also identified. RESULTS: The aquatic macrophyte stand extent varied among reservoirs and over sampling periods. Species richness showed only temporal variation. On the other hand, evenness and Shannon-Wiener index varied only among reservoirs. The beta diversity of macrophyte stands did not vary among reservoirs or over time, meaning that species variability among aquatic macrophyte stands was independent of the stand extent and reservoir eutrophication. Community composition depended on the reservoir and sampling period. CONCLUSIONS: Our results support our initial expectation that reservoirs of different degrees of eutrophication have different aquatic macrophyte communities. As a consequence, each reservoir had particular indicator species. Therefore, monitoring and management efforts must be offered for each reservoir individually.

  3. Time-Varying Networks of Inter-Ictal Discharging Reveal Epileptogenic Zone.

    Science.gov (United States)

    Zhang, Luyan; Liang, Yi; Li, Fali; Sun, Hongbin; Peng, Wenjing; Du, Peishan; Si, Yajing; Song, Limeng; Yu, Liang; Xu, Peng

    2017-01-01

    The neuronal synchronous discharging may cause an epileptic seizure. Currently, most of the studies conducted to investigate the mechanism of epilepsy are based on EEGs or functional magnetic resonance imaging (fMRI) recorded during the ictal discharging or the resting-state, and few studies have probed into the dynamic patterns during the inter-ictal discharging that are much easier to record in clinical applications. Here, we propose a time-varying network analysis based on adaptive directed transfer function to uncover the dynamic brain network patterns during the inter-ictal discharging. In addition, an algorithm based on the time-varying outflow of information derived from the network analysis is developed to detect the epileptogenic zone. The analysis performed revealed the time-varying network patterns during different stages of inter-ictal discharging; the epileptogenic zone was activated prior to the discharge onset then worked as the source to propagate the activity to other brain regions. Consistence between the epileptogenic zones detected by our proposed approach and the actual epileptogenic zones proved that time-varying network analysis could not only reveal the underlying neural mechanism of epilepsy, but also function as a useful tool in detecting the epileptogenic zone based on the EEGs in the inter-ictal discharging.

  4. Degrees of Cooperation in Household Consumption Models : A Revealed Preference Analysis

    NARCIS (Netherlands)

    Cherchye, L.J.H.; Demuynck, T.; de Rock, B.

    2009-01-01

    We develop a revealed preference approach to analyze non-unitary con- sumption models with intrahousehold allocations deviating from the cooper- ative (or Pareto e¢ cient) solution. At a theoretical level, we establish re- vealed preference conditions of household consumption models with varying

  5. Response of selected binomial coefficients to varying degrees of matrix sparseness and to matrices with known data interrelationships

    Science.gov (United States)

    Archer, A.W.; Maples, C.G.

    1989-01-01

    Numerous departures from ideal relationships are revealed by Monte Carlo simulations of widely accepted binomial coefficients. For example, simulations incorporating varying levels of matrix sparseness (presence of zeros indicating lack of data) and computation of expected values reveal that not only are all common coefficients influenced by zero data, but also that some coefficients do not discriminate between sparse or dense matrices (few zero data). Such coefficients computationally merge mutually shared and mutually absent information and do not exploit all the information incorporated within the standard 2 ?? 2 contingency table; therefore, the commonly used formulae for such coefficients are more complicated than the actual range of values produced. Other coefficients do differentiate between mutual presences and absences; however, a number of these coefficients do not demonstrate a linear relationship to matrix sparseness. Finally, simulations using nonrandom matrices with known degrees of row-by-row similarities signify that several coefficients either do not display a reasonable range of values or are nonlinear with respect to known relationships within the data. Analyses with nonrandom matrices yield clues as to the utility of certain coefficients for specific applications. For example, coefficients such as Jaccard, Dice, and Baroni-Urbani and Buser are useful if correction of sparseness is desired, whereas the Russell-Rao coefficient is useful when sparseness correction is not desired. ?? 1989 International Association for Mathematical Geology.

  6. Estimation of genomic prediction accuracy from reference populations with varying degrees of relationship.

    Directory of Open Access Journals (Sweden)

    S Hong Lee

    Full Text Available Genomic prediction is emerging in a wide range of fields including animal and plant breeding, risk prediction in human precision medicine and forensic. It is desirable to establish a theoretical framework for genomic prediction accuracy when the reference data consists of information sources with varying degrees of relationship to the target individuals. A reference set can contain both close and distant relatives as well as 'unrelated' individuals from the wider population in the genomic prediction. The various sources of information were modeled as different populations with different effective population sizes (Ne. Both the effective number of chromosome segments (Me and Ne are considered to be a function of the data used for prediction. We validate our theory with analyses of simulated as well as real data, and illustrate that the variation in genomic relationships with the target is a predictor of the information content of the reference set. With a similar amount of data available for each source, we show that close relatives can have a substantially larger effect on genomic prediction accuracy than lesser related individuals. We also illustrate that when prediction relies on closer relatives, there is less improvement in prediction accuracy with an increase in training data or marker panel density. We release software that can estimate the expected prediction accuracy and power when combining different reference sources with various degrees of relationship to the target, which is useful when planning genomic prediction (before or after collecting data in animal, plant and human genetics.

  7. Endogenous phosphorylation of basic protein in myelin of varying degrees of compaction

    International Nuclear Information System (INIS)

    Schulz, P.; Moscarello, M.A.; Cruz, T.F.

    1988-01-01

    Fractions containing myelin of varying degrees of compaction were prepared from human white matter. Protein kinase activity in these fractions was measured by using both endogenous and exogenous myelin basic protein (MBP) as substrates. In both cases, less compact myelin fractions possessed higher levels of protein kinase activity than the compact myelin fraction. In addition, the specific activity of phosphorylated basic protein was greater in the loosely compacted fractions than in compact multilamellar myelin. When basic protein in compact myelin or the myelin fractions was phosphorylated by the endogenous kinase, approximately 70% of the [ 32 P]phosphate was incorporated at a single site, identified as Ser-102. The remaining 30% was found in three other minor sites. Electron microscopy of less compact myelin showed it was composed of fewer lamellae which correlated with a relative decrease in the proportion of cationic charge isomers (microheteromers) when MBP was subjected to gel electrophoresis at alkaline pH. The shift in charge microheterogeneity of basic protein to the less cationic isomers in the less compact myelin fractions correlated with an increase in protein kinase activity and a greater specific activity of phosphorylated basic protein

  8. Environmental determinants of participation in tourism and recreation of people with varying degrees of disability.

    Science.gov (United States)

    Bergier, Barbara; Bergier, Józef; Kubińska, Zofia

    2010-01-01

    Environmental determinants for participation of disabled subjects in tourism and recreation comprise an important social problem. The amount and use of free time for individuals with disabilities in daily life, holidays, and vacation leave and the location for tourism and recreation were examined. Seven hundred and fifty individuals, aged 16-75 yr, with varying degrees of disability, from three eastern provinces of Poland: Podlaskie, Lubelskie and Podkarpackie were investigated. In these studies, a diagnostic survey method with the use of questionnaire, interviews, and analysis of data was carried out. It was found that individuals with disabilities have a significant amount of free time, which is usually spent with family and friends. Among the specific benefits of participation in physical activities are well-being, health improvement, and making new acquaintances. The main factors determining participation in tourism and recreation were price, a friendly group, and doctor recommendations.

  9. Vaginal Changes Due to Varying Degrees of Rectocele Prolapse: A Computational Study.

    Science.gov (United States)

    Chanda, Arnab; Meyer, Isuzu; Richter, Holly E; Lockhart, Mark E; Moraes, Fabia R D; Unnikrishnan, Vinu

    2017-10-01

    Pelvic organ prolapse (POP), downward descent of the pelvic organs resulting in a protrusion of the vagina, is a highly prevalent condition, responsible for 300,000 surgeries in the U.S. annually. Rectocele, a posterior vaginal wall (PVW) prolapse of the rectum, is the second most common type of POP after cystocele. A rectocele usually manifests itself along with other types of prolapse with multicompartment pelvic floor defects. To date, the specific mechanics of rectocele formation are poorly understood, which does not allow its early stage detection and progression prediction over time. Recently, with the advancement of imaging and computational modeling techniques, a plethora of finite element (FE) models have been developed to study vaginal prolapse from different perspectives and allow a better understanding of dynamic interactions of pelvic organs and their supporting structures. So far, most studies have focused on anterior vaginal prolapse (AVP) (or cystocele) and limited data exist on the role of pelvic muscles and ligaments on the development and progression of rectocele. In this work, a full-scale magnetic resonance imaging (MRI) based three-dimensional (3D) computational model of the female pelvic anatomy, comprising the vaginal canal, uterus, and rectum, was developed to study the effect of varying degrees (or sizes) of rectocele prolapse on the vaginal canal for the first time. Vaginal wall displacements and stresses generated due to the varying rectocele size and average abdominal pressures were estimated. Considering the direction pointing from anterior to posterior side of the pelvic system as the positive Y-direction, it was found that rectocele leads to negative Y-direction displacements, causing the vaginal cross section to shrink significantly at the lower half of the vaginal canal. Besides the negative Y displacements, the rectocele bulging was observed to push the PVW downward toward the vaginal hiatus, exhibiting the well-known "kneeling

  10. Participation of steroid hormones in providing physical activity in young people with varying degrees of physical fitness

    Directory of Open Access Journals (Sweden)

    Valeriy Levchenko

    2014-10-01

    Full Text Available Purpose: to investigate the dynamics of cortisol and testosterone in saliva of young people with varying degrees of physical fitness at an altitude stress test. Material and Methods: in a study involved 44 students – 29 girls and 15 boys, 17–20 years old. There was used immunosorbent assay to determine the level of cortisol and testosterone during tredmil-test, estimated on maximal aerobic power. Results: the relationship between the imbalance between cortisol and testosterone at an altitude under stress test in young people with low tolerance to physical activity in favor of cortisol. Conclusions: reduced tolerance to exercise, accompanied by high cortisol and testosterone index, decreased maximal aerobic power and tolerance.

  11. Varying acoustic-phonemic ambiguity reveals that talker normalization is obligatory in speech processing.

    Science.gov (United States)

    Choi, Ja Young; Hu, Elly R; Perrachione, Tyler K

    2018-04-01

    The nondeterministic relationship between speech acoustics and abstract phonemic representations imposes a challenge for listeners to maintain perceptual constancy despite the highly variable acoustic realization of speech. Talker normalization facilitates speech processing by reducing the degrees of freedom for mapping between encountered speech and phonemic representations. While this process has been proposed to facilitate the perception of ambiguous speech sounds, it is currently unknown whether talker normalization is affected by the degree of potential ambiguity in acoustic-phonemic mapping. We explored the effects of talker normalization on speech processing in a series of speeded classification paradigms, parametrically manipulating the potential for inconsistent acoustic-phonemic relationships across talkers for both consonants and vowels. Listeners identified words with varying potential acoustic-phonemic ambiguity across talkers (e.g., beet/boat vs. boot/boat) spoken by single or mixed talkers. Auditory categorization of words was always slower when listening to mixed talkers compared to a single talker, even when there was no potential acoustic ambiguity between target sounds. Moreover, the processing cost imposed by mixed talkers was greatest when words had the most potential acoustic-phonemic overlap across talkers. Models of acoustic dissimilarity between target speech sounds did not account for the pattern of results. These results suggest (a) that talker normalization incurs the greatest processing cost when disambiguating highly confusable sounds and (b) that talker normalization appears to be an obligatory component of speech perception, taking place even when the acoustic-phonemic relationships across sounds are unambiguous.

  12. Degree-strength correlation reveals anomalous trading behavior.

    Science.gov (United States)

    Sun, Xiao-Qian; Shen, Hua-Wei; Cheng, Xue-Qi; Wang, Zhao-Yang

    2012-01-01

    Manipulation is an important issue for both developed and emerging stock markets. Many efforts have been made to detect manipulation in stock markets. However, it is still an open problem to identify the fraudulent traders, especially when they collude with each other. In this paper, we focus on the problem of identifying the anomalous traders using the transaction data of eight manipulated stocks and forty-four non-manipulated stocks during a one-year period. By analyzing the trading networks of stocks, we find that the trading networks of manipulated stocks exhibit significantly higher degree-strength correlation than the trading networks of non-manipulated stocks and the randomized trading networks. We further propose a method to detect anomalous traders of manipulated stocks based on statistical significance analysis of degree-strength correlation. Experimental results demonstrate that our method is effective at distinguishing the manipulated stocks from non-manipulated ones. Our method outperforms the traditional weight-threshold method at identifying the anomalous traders in manipulated stocks. More importantly, our method is difficult to be fooled by colluded traders.

  13. Degree-strength correlation reveals anomalous trading behavior.

    Directory of Open Access Journals (Sweden)

    Xiao-Qian Sun

    Full Text Available Manipulation is an important issue for both developed and emerging stock markets. Many efforts have been made to detect manipulation in stock markets. However, it is still an open problem to identify the fraudulent traders, especially when they collude with each other. In this paper, we focus on the problem of identifying the anomalous traders using the transaction data of eight manipulated stocks and forty-four non-manipulated stocks during a one-year period. By analyzing the trading networks of stocks, we find that the trading networks of manipulated stocks exhibit significantly higher degree-strength correlation than the trading networks of non-manipulated stocks and the randomized trading networks. We further propose a method to detect anomalous traders of manipulated stocks based on statistical significance analysis of degree-strength correlation. Experimental results demonstrate that our method is effective at distinguishing the manipulated stocks from non-manipulated ones. Our method outperforms the traditional weight-threshold method at identifying the anomalous traders in manipulated stocks. More importantly, our method is difficult to be fooled by colluded traders.

  14. Performance equations of proton exchange membrane fuel cells with feeds of varying degrees of humidification

    International Nuclear Information System (INIS)

    Hsuen, Hsiao-Kuo; Yin, Ken-Ming

    2012-01-01

    Performance equations that describe the dependence of cell potential on current density for proton exchange membrane fuel cells (PEMFCs) with feeds of varying degrees of humidification have been formulated in algebraic form. The equations are developed by the reduction of a one-dimensional multi-domain model that takes into account, in details, the transport limitations of gas species, proton migration and electron conduction, electrochemical kinetics, as well as liquid water flow within the cathode, anode, and membrane. The model equations for the anode and membrane were integrated with those of the cathode developed in the previous studies to form a complete set of equations for one-dimensional single cell model. Because the transport equations for the anode diffuser can be solved analytically, calculations of integrals are only needed in the membrane and the two-phase region of cathode diffuser. The proposed approach greatly reduces the complexity of the model equations, and only iterations of a single algebraic equation are required to obtain final solutions. Since the performance equations are originated from a mechanistic one-dimensional model, all the parameters appearing in the equations are endowed with a precise physical significance.

  15. Assessment of metal contamination in the biota of four rivers experiencing varying degrees of human impact.

    Science.gov (United States)

    Bielmyer-Fraser, Gretchen K; Waters, Matthew Neal; Duckworth, Christina G; Patel, Pratik P; Webster, Benjamin Cole; Blocker, Amber; Crummey, Cliff Hunter; Duncan, Aundrea Nicole; Nwokike, Somuayiro Nadia; Picariello, Codie Richard; Ragan, James T; Schumacher, Erika L; Tucker, Rebecca Lea; Tuttle, Elizabeth Ann; Wiggins, Charlie Rufus

    2017-01-01

    Urbanization, agriculture, and other land transformations can affect water quality, decrease species biodiversity, and increase metal and nutrient concentrations in aquatic systems. Metal pollution, in particular, is a reported consequence of elevated anthropogenic inputs, especially from urbanized areas. The objectives of this study were to quantify metal (Cu, Al, Cd, Ni, and Pb) concentrations in the waters and biota of four streams in South Georgia, USA, and relate metal concentrations to land use and abiotic and biotic stream processes. Additionally, macrophytes, invertebrates, and fish were identified to assess biodiversity at each site. Metal concentrations in the three trophic levels differed among sites and species, correlating to differences in land use surrounding the rivers. The highest metal concentrations (except Al) were found in the streams most impacted by urbanization and development. Al concentrations were highest in streams surrounded by land dominated by forested areas. Metal content in macrophytes reflected metal concentrations in the water and was at least three orders of magnitude higher than any other trophic level. Despite metal concentration differences, all four streams contained similar water quality and were healthy based on macroinvertebrate community structure. This study provides insight into the impact of urbanization and the fate and effects of metals in river ecosystems with varying degrees of anthropogenic impact.

  16. Curing potential of experimental resin composites with systematically varying amount of bioactive glass: Degree of conversion, light transmittance and depth of cure.

    Science.gov (United States)

    Par, Matej; Spanovic, Nika; Bjelovucic, Ruza; Skenderovic, Hrvoje; Gamulin, Ozren; Tarle, Zrinka

    2018-06-17

    The aim of this work was to investigate the curing potential of an experimental resin composite series with the systematically varying amount of bioactive glass 45S5 by evaluating the degree of conversion, light transmittance and depth of cure. Resin composites based on a Bis-GMA/TEGDMA resin with a total filler load of 70 wt% and a variable amount of bioactive glass (0-40 wt%) were prepared. The photoinitiator system was camphorquinone and ethyl-4-(dimethylamino) benzoate. The degree of conversion and light transmittance were measured by Raman spectroscopy and UV-vis spectroscopy, respectively. The depth of cure was evaluated according to the classical ISO 4049 test. The initial introduction of bioactive glass into the experimental series diminished the light transmittance while the further increase in the bioactive glass amount up to 40 wt% caused minor variations with no clear trend. The curing potential of the experimental composites was similar to or better than that of commercial resin composites. However, unsilanized bioactive glass fillers demonstrated the tendency to diminish both the maximum attainable conversion and the curing efficiency at depth. Experimental composite materials containing bioactive glass showed a clinically acceptable degree of conversion and depth of cure. The degree of conversion and depth of cure were diminished by bioactive glass fillers in a dose-dependent manner, although light transmittance was similar among all of the experimental composites containing 5-40 wt% of bioactive glass. Reduced curing potential caused by the bioactive glass has possible consequences on mechanical properties and biocompatibility. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. The effect of varying degrees of stenosis on the characteristics of turbulent pulsatile flow through heart valves.

    Science.gov (United States)

    Bluestein, D; Einav, S

    1995-08-01

    Many problems and complications associated with heart valves are related to the dynamic behavior of the valve and the resultant unsteady flow patterns. An accurate depiction of the spatial and temporal velocity and rms distributions imparts better understanding of flow related valve complications, and may be used as a guideline in valve design. While the generalized correlation between increased turbulence level and the severity of the stenosis is well established, few studies addressed the issue of the intermittent nature of turbulence and its timing in the cardiac cycle, and almost none assessed the effect of a progressive stenosis on the flow characteristics through heart valves. In this experimental work we simulated the type of flow which is present in normal and stenosed valves and conducted a comprehensive investigation of valve hemodynamics, valvular turbulence and morphology under varying degrees of stenosis. The characteristics of valves and stenoses were simulated closely, to achieve the flow conditions that initiate turbulent flow conditions. Laser Doppler anemometry (LDA) measurements were carried out in a pulse duplicator system distal to trileaflet polyurethane prosthetic heart valves, installed at mitral and aortic positions. The effect of the degree of the stenosis was comparatively studied through the structure of the turbulent jets emerging from normal and stenotic heart valves. Maximum turbulence level was achieved during the decelerating phase and correlated to the severity of the stenosis, followed by relaminarization of the flow during the acceleration phase. The intermittent nature of the turbulence emphasized the importance of realizing the timing of the turbulence production and its spatial location for optimizing current valve designs. The plug flow through the normal aortic valve prosthesis was replaced by jet like behavior for a 65% stenosis, with the jet becoming narrower and stronger for a 90% stenosis. The morphology of the velocity

  18. Health-related quality of life deficits associated with varying degrees of disease severity in type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Majumdar Sumit R

    2003-12-01

    Full Text Available Abstract Background Diabetes is a chronic medical condition accompanied by a considerable health-related quality of life (HRQL burden. The purpose of this analysis was to use generic measures of HRQL to describe HRQL deficits associated with varying degrees of severity of type 2 diabetes. Methods The RAND-12 physical and mental health composites (PHC and MHC, respectively and Health Utilities Index Mark 3 (HUI3 were self-completed by 372 subjects enrolled in a prospective, controlled study of an intervention to improve care for individuals with type 2 diabetes in rural communities. Analysis of covariance was used to assess differences in HRQL according to disease severity and control of blood glucose. Disease severity was defined in terms of treatment intensity, emergency room visits and absenteeism from work specifically attributable to diabetes. To control for potential confounding, the analysis was adjusted for important sociodemographic and clinical characteristics. Results The PHC and MHC were significantly lower for individuals treated with insulin as compared to diet alone (PHC: 41.01 vs 45.11, MHC: 43.23 vs 47.00, p Conclusions We concluded that generic measures of HRQL captured deficits associated with more severe disease in type 2 diabetes.

  19. Heat treatment of the common furniture beetle Anobium punctatum (Coleoptera: Anobiidae), at temperature between 45 degrees and 54 degrees C. under dry and humid conditions

    DEFF Research Database (Denmark)

    Hansen, Lise Stengaard; Jensen, Karl-Martin Vagn

    1998-01-01

    The combinations of exposure times and temperatures (45 degrees to 54 degrees C.) without addition of moisture necessary to obtain 100 per cent mortality were determined on all stages of commn furniture beetle, Anobium punctatum. Lethal combinations vary from minutes at 46 degrees to 5 minutes...

  20. [Morphological characteristics of kidneys connective tissue of mature fetuses and newborns from mothers, whose pregnancy was complicated by preeclampsia of varying degrees of severity].

    Science.gov (United States)

    Sorokina, Iryna V; Myroshnychenko, Mykhailo S; Kapustnyk, Nataliia V; Khramova, Tetyana O; Dehtiarova, Oksana V; Danylchenko, Svitlana I

    2018-01-01

    Introduction: The kidneys connective tissue condition in the antenatal period affects the formation of tissues and it changes with the development of various general pathological processes in this organ. The aim of the study was to identify the morphological features of kidneys connective tissue of fetuses and newborns from mothers whose pregnancy was complicated by preeclampsia of varying degrees of severity. Materials and methods: The material of the study was the tissue of kidneys of mature fetuses and newborns from mothers with physiological pregnancy (28 cases), as well as from mothers whose pregnancy was complicated by preeclampsia of varying degrees of severity (78 cases). Immunohistochemical study was performed by an indirect Coons method according to M. Brosman's technique using monoclonal antibodies to collagen type I, III and IV. Results: The kidneys connective tissue of fetuses and newborns developing under the maternal preeclampsia conditions is characterized by the qualitative and quantitative changes that indicate the development of sclerotic processes in this organ, the severity of which increase with the age and with the increase of the maternal preeclampsia severity. Qualitative changes are characterized by an increase of the fibrous component, thickening of the bundles of connective tissue fibers, and a decrease in the distance between them. Quantitative changes are characterized by a pronounced predominance of collagen fibers over elastic fibers, almost total absence in some field of view elastic fibers and the violation of the content of collagen type I, III and IV. Conclusion: Maternal preeclampsia underlies the development of qualitative and quantitative changes in kidneys connective tissue of fetuses and newborns, which as a result will lead to disruption of the functions of these organs in such children.

  1. A dosing algorithm for metformin based on the relationships between exposure and renal clearance of metformin in patients with varying degrees of kidney function.

    Science.gov (United States)

    Duong, Janna K; Kroonen, M Y A M; Kumar, S S; Heerspink, H L; Kirkpatrick, C M; Graham, G G; Williams, K M; Day, R O

    2017-08-01

    The aims of this study were to investigate the relationship between metformin exposure, renal clearance (CL R ), and apparent non-renal clearance of metformin (CL NR /F) in patients with varying degrees of kidney function and to develop dosing recommendations. Plasma and urine samples were collected from three studies consisting of patients with varying degrees of kidney function (creatinine clearance, CL CR ; range, 14-112 mL/min). A population pharmacokinetic model was built (NONMEM) in which the oral availability (F) was fixed to 0.55 with an estimated inter-individual variability (IIV). Simulations were performed to estimate AUC 0-τ , CL R , and CL NR /F. The data (66 patients, 327 observations) were best described by a two-compartment model, and CL CR was a covariate for CL R . Mean CL R was 17 L/h (CV 22%) and mean CL NR /F was 1.6 L/h (69%).The median recovery of metformin in urine was 49% (range 19-75%) over a dosage interval. When CL R increased due to improved renal function, AUC 0-τ decreased proportionally, while CL NR /F did not change with kidney function. Target doses (mg/day) of metformin can be reached using CL CR /3 × 100 to obtain median AUC 0-12 of 18-26 mg/L/h for metformin IR and AUC 0-24 of 38-51 mg/L/h for metformin XR, with C max  kidney function to maintain consistent drug exposure. However, there is still marked IIV and therapeutic drug monitoring of metformin plasma concentrations is recommended.

  2. The co-movement of monetary policy and its time-varying nature: A DCCA approach

    Science.gov (United States)

    Rohit, Abhishek; Mitra, Subrata Kumar

    2018-02-01

    Employing a novel methodology of DCCA cross-correlation coefficient (ρDCCA), this study attempts to provide fresh evidences for the co-movement of monetary policies of the advanced (AEs) as well as the emerging economies (EMEs) vis-à-vis the United States. A higher degree of monetary co-movement as measured by ρDCCA values, is identified for the AEs as compared to the EMEs. Lower co-movement of monetary policy is especially noticeable in the short run for EMEs. We further investigate the time-varying nature of such co-movements for the AEs by splitting the period (1980-2014) into four sub periods and also by performing a rolling window estimation for the entire period to reveal smoother dynamics. Significant evidence of higher monetary coordination is revealed for sub-periods with stronger trade and financial linkages.

  3. Scholarship in nursing: Degree-prepared nurses versus diploma ...

    African Journals Online (AJOL)

    All but one (n = 18) nursing educators who obtained a degree as first qualification are educators in the private sector that include both universities as well as nursing colleges of private hospital groups. Data further revealed that most nurse educators and those in managerial positions were degree prepared. More degree ...

  4. 7 CFR 29.6081 - Elements of quality and degrees of each element.

    Science.gov (United States)

    2010-01-01

    ..., but the actual value of each degree varies with type and group. Elements Degrees Body Heavy Medium Thin. Maturity Immature Mature Ripe. Leaf structure Close Firm Open. Elasticity Inelastic Semielastic...

  5. 7 CFR 29.3586 - Elements of quality and degrees of each element.

    Science.gov (United States)

    2010-01-01

    ... value, but the actual value of each degree varies with type, group, and grade. Elements Degrees Maturity.... Elasticity Inelastic Semielastic Elastic. Width Narrow Normal Spready. Uniformity (1) (1) (1). Injury...

  6. Modelling suction instabilities in soils at varying degrees of saturation

    Directory of Open Access Journals (Sweden)

    Buscarnera Giuseppe

    2016-01-01

    Full Text Available Wetting paths imparted by the natural environment and/or human activities affect the state of soils in the near-surface, promoting transitions across different regimes of saturation. This paper discusses a set of techniques aimed at quantifying the role of hydrologic processes on the hydro-mechanical stability of soil specimens subjected to saturation events. Emphasis is given to the mechanical conditions leading to coupled flow/deformation instabilities. For this purpose, energy balance arguments for three-phase systems are used to derive second-order work expressions applicable to various regimes of saturation. Controllability analyses are then performed to relate such work input with constitutive singularities that reflect the loss of strength under coupled and/or uncoupled hydro-mechanical forcing. A suction-dependent plastic model is finally used to track the evolution of stability conditions in samples subjected to wetting, thus quantifying the growth of the potential for coupled failure modes upon increasing degree of saturation. These findings are eventually linked with the properties of the field equations that govern pore pressure transients, thus disclosing a conceptual link between the onset of coupled hydro-mechanical failures and the evolution of suction with time. Such results point out that mathematical instabilities caused by a non-linear suction dependent behaviour play an important role in the advanced constitutive and/or numerical tools that are commonly used for the analysis of geomechanical problems in the unsaturated zone, and further stress that the relation between suction transients and soil deformations is a key factor for the interpretation of runaway failures caused by intense saturation events.

  7. Importance of small-degree nodes in assortative networks with degree-weight correlations

    Science.gov (United States)

    Ma, Sijuan; Feng, Ling; Monterola, Christopher Pineda; Lai, Choy Heng

    2017-10-01

    It has been known that assortative network structure plays an important role in spreading dynamics for unweighted networks. Yet its influence on weighted networks is not clear, in particular when weight is strongly correlated with the degrees of the nodes as we empirically observed in Twitter. Here we use the self-consistent probability method and revised nonperturbative heterogenous mean-field theory method to investigate this influence on both susceptible-infective-recovered (SIR) and susceptible-infective-susceptible (SIS) spreading dynamics. Both our simulation and theoretical results show that while the critical threshold is not significantly influenced by the assortativity, the prevalence in the supercritical regime shows a crossover under different degree-weight correlations. In particular, unlike the case of random mixing networks, in assortative networks, the negative degree-weight correlation leads to higher prevalence in their spreading beyond the critical transmissivity than that of the positively correlated. In addition, the previously observed inhibition effect on spreading velocity by assortative structure is not apparent in negatively degree-weight correlated networks, while it is enhanced for that of the positively correlated. Detailed investigation into the degree distribution of the infected nodes reveals that small-degree nodes play essential roles in the supercritical phase of both SIR and SIS spreadings. Our results have direct implications in understanding viral information spreading over online social networks and epidemic spreading over contact networks.

  8. Families of Smooth Rational Curves of Small Degree on the Fano Variety of Degree 5 of Main Series

    Directory of Open Access Journals (Sweden)

    M. S. Omelkova

    2013-01-01

    Full Text Available In this paper we consider some families of smooth rational curves of degree 2, 3 and 4 on a smooth Fano threefold X which is a linear section of the Grassmanian G(1, 4 under the Pl¨ucker embedding. We prove that these families are irreducible. The proof of the irreducibility of the families of curves of degree d is based on the study of degeneration of a rational curve of degree d into a curve which decomposes into an irreducible rational curve of degree d−1 and a projective line intersecting transversally at a point. We prove that the Hilbert scheme of curves of degree d on X is smooth at the point corresponding to such a reducible curve. Then calculations in the framework of deformation theory show that such a curve varies into a smooth rational curve of degree d. Thus, the set of reducible curves of degree d of the above type lies in the closure of a unique component of the Hilbert scheme of smooth rational curves of degree d on X. From this fact and the irreducibility of the Hilbert scheme of smooth rational curves of degree d on the Grassmannian G(1, 4 one deduces the irreducibility of the Hilbert scheme of smooth rational curves of degree d on a general Fano threefold X.

  9. VARYING DEGREE OF GRAFTING COMPATIBILITY BETWEEN CV. CHARDONNAY, MERLOT AND DIFFERENT GRAPEVINE ROOTSTOCKS

    Directory of Open Access Journals (Sweden)

    Slavica TODIĆ

    2006-02-01

    matter content in mature shoots is showing good maturity of shoots in cv. Chardonnay in all experiment combinations and varies from 53% up to 54%. Clones of Merlot, in this investigation, showed the highest level of compatibility with rootstock Kober 5BB. Percentage of I class grafted rootlings on this rootstock for clone R18 was 66%, and for clone MCL 519 was 62%. In the same experiment combination the highest root weight was established as well. The low degree of grafting compatibility was obtained by grafting Merlot clones on rootstock SO4, that is shown by signifi cantly lower percentage of produced I class grafted rootlings in relation to obtained values by grafting on other examined grapevine rootstocks (clone R18/SO4 – 51%; clone MCL519/SO4 – 50%.

  10. Performance and microbial community composition dynamics of aerobic granular sludge from sequencing batch bubble column reactors operated at 20 degrees C, 30 degrees C, and 35 degrees C.

    Science.gov (United States)

    Ebrahimi, Sirous; Gabus, Sébastien; Rohrbach-Brandt, Emmanuelle; Hosseini, Maryam; Rossi, Pierre; Maillard, Julien; Holliger, Christof

    2010-07-01

    Two bubble column sequencing batch reactors fed with an artificial wastewater were operated at 20 degrees C, 30 degrees C, and 35 degrees C. In a first stage, stable granules were obtained at 20 degrees C, whereas fluffy structures were observed at 30 degrees C. Molecular analysis revealed high abundance of the operational taxonomic unit 208 (OTU 208) affiliating with filamentous bacteria Leptothrix spp. at 30 degrees C, an OTU much less abundant at 20 degrees C. The granular sludge obtained at 20 degrees C was used for the second stage during which one reactor was maintained at 20 degrees C and the second operated at 30 degrees C and 35 degrees C after prior gradual increase of temperature. Aerobic granular sludge with similar physical properties developed in both reactors but it had different nutrient elimination performances and microbial communities. At 20 degrees C, acetate was consumed during anaerobic feeding, and biological phosphorous removal was observed when Rhodocyclaceae-affiliating OTU 214 was present. At 30 degrees C and 35 degrees C, acetate was mainly consumed during aeration and phosphorous removal was insignificant. OTU 214 was almost absent but the Gammaproteobacteria-affiliating OTU 239 was more abundant than at 20 degrees C. Aerobic granular sludge at all temperatures contained abundantly the OTUs 224 and 289 affiliating with Sphingomonadaceae indicating that this bacterial family played an important role in maintaining stable granular structures.

  11. Physics Doctorates One Year after Degree: Data from the Follow-up Survey of Degree Recipients from the Classes of 2013 and 2014. Focus On

    Science.gov (United States)

    Pold, Jack; Mulvey, Patrick

    2016-01-01

    This report presents trend data on the status of physics PhDs one year after receiving their degree. For the last decade postdoctoral fellowships were the most commonly reported positions taken by physics PhDs in the year after receiving their degree. The type of initial employment for of physics PhDs varied depending on the subfield of their…

  12. Measurement of the oxidation of spent fuel between 140/degree/ and 225/degree/C by thermogravimetric analysis

    International Nuclear Information System (INIS)

    Woodley, R.E.; Einziger, R.E.; Buchanan, H.C.

    1988-09-01

    A series of PWR spent fuel samples from Turkey Point Unit 3 have been oxidized at temperatures between 140/degree/ and 225/degree/C in air atmospheres with dew points between 14.5/degree/ and /minus/70/degree/C, using a thermogravimetric analysis system (TGA). Tests lasted between 400 and 2100 hours. At the conclusion of a test, the atmosphere was sampled to determine the release of fission gas during testing, and the fuel samples were analyzed for microstructural changes. It appears that the mechanism for oxidation of spent fuel to U/sub 3/O/sub 7/ takes place in two steps that occur somewhat simultaneously. Oxygen migrates along the grain boundaries, which are oxidized and enlarged. The grains oxidize by the inward progression of a layer of U/sub 4/O/sub 9/ saturated with oxygen. A simplified model of the mechanism, which considers oxygen diffusion through the product layer as the rate-controlling step, yields an activation energy of 27 /plus minus/ 4 kcal/mol. Moisture, between dew points of /minus/70/degree/ to +14.5/degree/C, i.e., water vapor partial pressures varying over four orders of magnitude, had no significant effect on the oxidation rate. 34 refs., 12 figs., 6 tabs

  13. Degree-degree correlations in random graphs with heavy-tailed degrees

    NARCIS (Netherlands)

    Hofstad, van der R.W.; Litvak, N.

    2014-01-01

    Mixing patterns in large self-organizing networks, such as the Internet, the World Wide Web, social, and biological networks are often characterized by degree-degree dependencies between neighboring nodes. In assortative networks, the degree-degree dependencies are positive (nodes with similar

  14. Degree-Degree Dependencies in Random Graphs with Heavy-Tailed Degrees

    NARCIS (Netherlands)

    van der Hofstad, Remco; Litvak, Nelly

    2014-01-01

    Mixing patterns in large self-organizing networks, such as the Internet, the World Wide Web, social, and biological networks are often characterized by degree-degree dependencies between neighboring nodes. In assortative networks, the degree-degree dependencies are positive (nodes with similar

  15. Effect of thermal processing on silver thin films of varying thickness deposited on zinc oxide and indium tin oxide

    International Nuclear Information System (INIS)

    Sivaramakrishnan, K.; Ngo, A. T.; Alford, T. L.; Iyer, S.

    2009-01-01

    Silver films of varying thicknesses (25, 45, and 60 nm) were deposited on indium tin oxide (ITO) on silicon and zinc oxide (ZnO) on silicon. The films were annealed in vacuum for 1 h at different temperatures (300-650 deg. C). Four-point-probe measurements were used to determine the resistivity of the films. All films showed an abrupt change in resistivity beyond an onset temperature that varied with thickness. Rutherford backscattering spectrometry measurements revealed agglomeration of the Ag films upon annealing as being responsible for the resistivity change. X-ray pole figure analysis determined that the annealed films took on a preferential texturing; however, the degree of texturing was significantly higher in Ag/ZnO/Si than in Ag/ITO/Si samples. This observation was accounted for by interface energy minimization. Atomic force microscopy (AFM) measurements revealed an increasing surface roughness of the annealed films with temperature. The resistivity behavior was explained by the counterbalancing effects of increasing crystallinity and surface roughness. Average surface roughness obtained from the AFM measurements were also used to model the agglomeration of Ag based on Ostwald ripening theory

  16. The Degree of Financial Liberalization and Aggregated Stock-return Volatility in Emerging Markets

    NARCIS (Netherlands)

    Umutlu, M.; Akdeniz, L.; Salih, A.A.

    2009-01-01

    In this study, we address whether the degree of financial liberalization affects the aggregated total volatility of stock returns by considering the time-varying nature of financial liberalization. We also explore channels through which the degree of financial liberalization impacts aggregated total

  17. Effect of Crystallisation Degree on Hardness of Basaltic Glass-Ceramics

    DEFF Research Database (Denmark)

    Jensen, Martin; Smedskjær, Morten Mattrup; Yue, Yuanzheng

    The dependence of hardness of basaltic glass-ceramics on their crystallisation degree has been explored by means of differential scanning calorimetry, optical microscopy, X-ray diffraction, and Vickers indentation. Different degrees of crystallisation in the basaltic glasses have been obtained...... by varying the temperature of heat treatment. The change of the relative degree of crystallisation with the heat treatment temperature can be described by an empirical model established in this work. The predominant crystalline phase in the glass has been identified as the pyroxene augite. The hardness...... principle calculations. It is found that the hardness of the glass phase decreases slightly with an increase in the degree of crystallisation, while that of the augite phase drastically decreases....

  18. g-boson degree of freedom in vibrational regions

    International Nuclear Information System (INIS)

    Di Yaomin

    1991-01-01

    The g-boson degree of freedom in the vibrational regions is discussed in term of the energies and the electromagnetic transitions. Several closed expressions for the rates of M1, E2 transitions and the E2, M1 mixing ratios are obtained. Some survey is made and it reveals it is meaningful to investigate the g-boson degree of freedom in those regions

  19. Specific heats of lunar surface materials from 90 to 350 degrees Kelvin

    Science.gov (United States)

    Robie, R.A.; Hemingway, B.S.; Wilson, W.H.

    1970-01-01

    The specific heats of lunar samples 10057 and 10084 returned by the Apollo 11 mission have been measured between 90 and 350 degrees Kelvin by use of an adiabatic calorimeter. The samples are representative of type A vesicular basalt-like rocks and of finely divided lunar soil. The specific heat of these materials changes smoothly from about 0.06 calorie per gram per degree at 90 degrees Kelvin to about 0.2 calorie per gram per degree at 350 degrees Kelvin. The thermal parameter ??=(k??C)-1/2 for the lunar surface will accordingly vary by a factor of about 2 between lunar noon and midnight.

  20. Positive Almost Periodic Solutions for a Time-Varying Fishing Model with Delay

    Directory of Open Access Journals (Sweden)

    Xia Li

    2011-01-01

    Full Text Available This paper is concerned with a time-varying fishing model with delay. By means of the continuation theorem of coincidence degree theory, we prove that it has at least one positive almost periodic solution.

  1. Microstructure, mechanical, and in vitro properties of mica glass-ceramics with varying fluorine content.

    Science.gov (United States)

    Molla, Atiar Rahaman; Basu, Bikramjit

    2009-04-01

    The design and development of glass ceramic materials provide us the unique opportunity to study the microstructure development with changes in either base glass composition or heat treatment conditions as well as to understand processing-microstructure-property (mechanical/biological) relationship. In the present work, it is demonstrated how various crystal morphology can develop when F(-) content in base glass (K(2)O-B(2)O(3)-Al(2)O(3)-SiO(2)-MgO-F) is varied in the range of 1.08-3.85% and when all are heat treated at varying temperatures of 1000-1120 degrees C. For some selected heat treatment temperature, the heat treatment time is also varied over 4-24 h. It was established that with increase in fluoride content in the glass composition, the crystal volume fraction of the glass-ceramic decreases. Using 1.08% fluoride, more than 80% crystal volume fraction could be achieved in the K(2)O-B(2)O(3)-Al(2)O(3)-SiO(2)-MgO-F system. It was observed that with lower fluoride content glass-ceramic, if heated at 1040 degrees C for 12 h, an oriented microstructure with 'envelop like' crystals can develop. For glass ceramics with higher fluorine content (2.83% or 3.85%), hexagonal-shaped crystals are formed. Importantly, high hardness of around 8 GPa has been measured in glass ceramics with maximum amount of crystals. The three-point flexural strength and elastic modulus of the glass-ceramic (heat treated at 1040 degrees C for 24 h) was 80 MPa and 69 GPa of the sample containing 3.85% fluorine, whereas, similar properties obtained for the sample containing 1.08% F(-) was 94 MPa and 57 GPa, respectively. Further, in vitro dissolution study of the all three glass-ceramic composition in artificial saliva (AS) revealed that leached fluoride ion concentration was 0.44 ppm, when the samples were immersed in AS for 8 weeks. This was much lower than the WHO recommended safety limits of 1.5 ppm. Among all the investigated glass-ceramic samples, the glass ceramic with 3.85% F

  2. Pharmacokinetics and Safety of a Single Oral Dose of Mirogabalin in Japanese Subjects With Varying Degrees of Renal Impairment.

    Science.gov (United States)

    Kato, Manabu; Tajima, Naoyuki; Shimizu, Takako; Sugihara, Masahiro; Furihata, Kenichi; Harada, Kazuhiro; Ishizuka, Hitoshi

    2018-01-01

    Mirogabalin (DS-5565) is a novel preferentially selective α 2 δ-1 ligand being developed for the treatment of diabetic peripheral neuropathic pain and postherpetic neuralgia. The current multicenter open-label study determined the effect of varying degrees of renal impairment on the pharmacokinetics and safety of a single dose of mirogabalin 5 mg in Japanese subjects. A total of 30 subjects (6 subjects per renal function category [normal, mild, moderate, or severe impairment; and end-stage renal disease (ESRD)]) were enrolled and completed the study. The AUC last increased with severity of renal impairment; the geometric least-squares mean ratios of AUC last compared with subjects with normal renal function were 1.3, 1.9, 3.6, and 5.3 for patients with mild, moderate, and severe impairment and ESRD, respectively. In accordance with this AUC last increase, apparent total body clearance (CL/F), renal clearance (CLr), and the cumulative percentage of mirogabalin dose excreted into urine all decreased with severity of renal impairment. There were no deaths and no severe treatment-related adverse events (TEAEs), serious TEAEs, or TEAEs resulting in study discontinuation. Mirogabalin was well tolerated in Japanese subjects with normal renal function and those with mild to severe renal impairment. It was also tolerated in subjects with ESRD but with a higher incidence of TEAEs. The most frequently reported TEAEs were dizziness (ESRD, n = 3), somnolence (ESRD, n = 2), and vomiting (ESRD, n = 2). Based on these data, a mirogabalin dose adjustment will be considered in Japanese subjects with moderate to severe renal impairment and those with ESRD. © 2017, The Authors. The Journal of Clinical Pharmacology published by Wiley Periodicals, Inc. on behalf of American College of Clinical Pharmacology.

  3. Adolescent obesity and future college degree attainment.

    Science.gov (United States)

    Fowler-Brown, Angela G; Ngo, Long H; Phillips, Russell S; Wee, Christina C

    2010-06-01

    The current impact of adolescent obesity on educational attainment is not clear. The objectives of our study were to determine whether adolescent obesity is associated with college degree attainment and how this association may have changed over time. We used data from a contemporary national cohort of over 4,000 persons who were adolescents (aged 14-18) in 1997 to assess the relationship between adolescent obesity and education. To assess for changes in this relationship over time, we also analyzed an older, similarly structured cohort of over 3,000 persons who were adolescents (aged 16-18) in 1981. Our primary outcome was college degree completion. We found that in the older cohort (adolescents in 1979), there were no differences in college degree attainment by adolescent weight status before and after adjustment. However, unadjusted analysis of the contemporary cohort (adolescents in 1997) demonstrated that those who were normal weight as adolescents had a higher prevalence of college degree attainment at follow-up compared to obese adolescents (24% vs. 10%). After adjustment for socio-demographic variables (age, sex, race, height, parental income-to-poverty ratio, parental education, aptitude test scores), obese adolescents were less likely to have attained a college degree compared to normal weight peers (adjusted risk ratio 0.61 95% confidence interval 0.38-0.83). Expectations for a future college degree did not vary by weight status and did not explain this observation. In conclusion, adolescent obesity is associated with lower likelihood of college completion. This relationship was not observed in an older cohort of adolescents.

  4. Physical properties of peats as related to degree of decomposition

    Science.gov (United States)

    D.H. Boelter

    1969-01-01

    Important physical characteristics, such as water retention, water yield coefficient, and hydraulic conductivity, vary greatly for representative northern Minnesota peat materials. The differences are related to the degree of decomposition, which largely determines the porosity and pore size distribution. Fiber content (> 0.1 mm) and bulk density are properties...

  5. Characteristics of the Equine Degree Department: Budgeting and the Department Chairperson.

    Science.gov (United States)

    Matte, Grace E.

    This study examined characteristics of 73 equine degree programs in the United States, the training and duties of their department chairpersons, and their budgetary processes. Analysis of data from questionnaire responses revealed a large variety of equine degree and minor programs, with annual budgets ranging from $2,000 to $757,200. Public…

  6. Surface Wave Detection and Measurement Using a One Degree Global Dispersion Grid

    National Research Council Canada - National Science Library

    Stevens, Jeffry L

    2006-01-01

    .... The models consist of approximately 550 distinct crust and upper mantle structures, with surface layering and/or ocean depths that vary on a one-degree grid to create a total of 64,800 earth models...

  7. Central recirculation zone analysis in an unconfined tangential swirl burner with varying degrees of premixing

    Energy Technology Data Exchange (ETDEWEB)

    Valera-Medina, A. [CIATEQ, Parque Industrial Bernardo Quintana, Turbomachinery Department, Queretaro (Mexico); Syred, N.; Kay, P.; Griffiths, A. [Cardiff University, School of Engineering, Cardiff, Wales (United Kingdom)

    2011-06-15

    Swirl-stabilised combustion is one of the most widely used techniques for flame stabilisation, uses ranging from gas turbine combustors to pulverised coal-fired power stations. In gas turbines, lean premixed systems are of especial importance, giving the ability to produce low NOx systems coupled with wide stability limits. The common element is the swirl burner, which depends on the generation of an aerodynamically formed central recirculation zone (CRZ) and which serves to recycle heat and active chemical species to the root of the flame as well as providing low-velocity regions where the flame speed can match the local flow velocity. Enhanced mixing in and around the CRZ is another beneficial feature. The structure of the CRZ and hence that of the associated flames, stabilisation and mixing processes have shown to be extremely complex, three-dimensional and time dependent. The characteristics of the CRZ depend very strongly on the level of swirl (swirl number), burner configuration, type of flow expansion, Reynolds number (i.e. flowrate) and equivalence ratio. Although numerical methods have had some success when compared to experimental results, the models still have difficulties at medium to high swirl levels, with complex geometries and varied equivalence ratios. This study thus focuses on experimental results obtained to characterise the CRZ formed under varied combustion conditions with different geometries and some variation of swirl number in a generic swirl burner. CRZ behaviour has similarities to the equivalent isothermal state, but is strongly dependent on equivalence ratio, with interesting effects occurring with a high-velocity fuel injector. Partial premixing and combustion cause more substantive changes to the CRZ than pure diffusive combustion. (orig.)

  8. Time-varying long term memory in the European Union stock markets

    Science.gov (United States)

    Sensoy, Ahmet; Tabak, Benjamin M.

    2015-10-01

    This paper proposes a new efficiency index to model time-varying inefficiency in stock markets. We focus on European stock markets and show that they have different degrees of time-varying efficiency. We observe that the 2008 global financial crisis has an adverse effect on almost all EU stock markets. However, the Eurozone sovereign debt crisis has a significant adverse effect only on the markets in France, Spain and Greece. For the late members, joining EU does not have a uniform effect on stock market efficiency. Our results have important implications for policy makers, investors, risk managers and academics.

  9. Theileria parva antigens recognized by CD8+ T cells show varying degrees of diversity in buffalo-derived infected cell lines.

    Science.gov (United States)

    Sitt, Tatjana; Pelle, Roger; Chepkwony, Maurine; Morrison, W Ivan; Toye, Philip

    2018-05-06

    The extent of sequence diversity among the genes encoding 10 antigens (Tp1-10) known to be recognized by CD8+ T lymphocytes from cattle immune to Theileria parva was analysed. The sequences were derived from parasites in 23 buffalo-derived cell lines, three cattle-derived isolates and one cloned cell line obtained from a buffalo-derived stabilate. The results revealed substantial variation among the antigens through sequence diversity. The greatest nucleotide and amino acid diversity were observed in Tp1, Tp2 and Tp9. Tp5 and Tp7 showed the least amount of allelic diversity, and Tp5, Tp6 and Tp7 had the lowest levels of protein diversity. Tp6 was the most conserved protein; only a single non-synonymous substitution was found in all obtained sequences. The ratio of non-synonymous: synonymous substitutions varied from 0.84 (Tp1) to 0.04 (Tp6). Apart from Tp2 and Tp9, we observed no variation in the other defined CD8+ T cell epitopes (Tp4, 5, 7 and 8), indicating that epitope variation is not a universal feature of T. parva antigens. In addition to providing markers that can be used to examine the diversity in T. parva populations, the results highlight the potential for using conserved antigens to develop vaccines that provide broad protection against T. parva.

  10. Degree-degree correlations in directed networks with heavy-tailed degrees

    NARCIS (Netherlands)

    van der Hoorn, W.L.F.; Litvak, Nelli

    2013-01-01

    In network theory, Pearson's correlation coefficients are most commonly used to measure the degree assortativity of a network. We investigate the behavior of these coefficients in the setting of directed networks with heavy-tailed degree sequences. We prove that for graphs where the in- and

  11. Degree-degree dependencies in directed networks with heavy-tailed degrees

    NARCIS (Netherlands)

    van der Hoorn, W.L.F.; Litvak, Nelly

    2015-01-01

    In network theory, Pearson’s correlation coefficients are most commonly used to measure the degree assortativity of a network. We investigate the behavior of these coefficients in the setting of directed networks with heavy-tailed degree sequences. We prove that for graphs where the in- and

  12. Exponential stability of fuzzy cellular neural networks with constant and time-varying delays

    International Nuclear Information System (INIS)

    Liu Yanqing; Tang Wansheng

    2004-01-01

    In this Letter, the global stability of delayed fuzzy cellular neural networks (FCNN) with either constant delays or time varying delays is proposed. Firstly, we give the existence and uniqueness of the equilibrium point by using the theory of topological degree and the properties of nonsingular M-matrix and the sufficient conditions for ascertaining the global exponential stability by constructing a suitable Lyapunov functional. Secondly, the criteria for guaranteeing the global exponential stability of FCNN with time varying delays are given and the estimation of exponential convergence rate with regard to speed of vary of delays is presented by constructing a suitable Lyapunov functional

  13. Branched Chain Amino Acids Are Associated with Insulin Resistance Independent of Leptin and Adiponectin in Subjects with Varying Degrees of Glucose Tolerance.

    Science.gov (United States)

    Connelly, Margery A; Wolak-Dinsmore, Justyna; Dullaart, Robin P F

    2017-05-01

    Branched chain amino acids (BCAA) may be involved in the pathogenesis of insulin resistance and are associated with type 2 diabetes mellitus (T2DM) development. Adipokines such as leptin and adiponectin influence insulin resistance and reflect adipocyte dysfunction. We examined the extent to which the association of BCAA with insulin resistance is attributable to altered leptin and adiponectin levels in individuals with varying degrees of glucose tolerance. BCAA were measured by nuclear magnetic resonance, whereas leptin and adiponectin were measured by immunoassay, in subjects with normal fasting glucose (n = 30), impaired fasting glucose (n = 25), and T2DM (n = 15). Insulin resistance was estimated by homeostasis model assessment (HOMAir). BCAA were higher in men than in women (P BCAA were correlated with HOMAir (r = 0.46; P  0.05). Multivariable linear regression analysis, adjusting for age, sex, T2DM, and body mass index (BMI), demonstrated that BCAA were positively associated with HOMAir (β = 0.242, P = 0.023). When BCAA, leptin, and adiponectin were included together, the positive relationship of HOMAir with BCAA (β = 0.275, P = 0.012) remained significant. Insulin resistance was associated with BCAA. This association remained after adjusting for age, sex, T2DM, BMI, as well as leptin and adiponectin. It is unlikely that the relationship of insulin resistance with BCAA is to a major extent attributable to effects of leptin and adiponectin.

  14. Bacterial Sulfate Reduction Above 100-Degrees-C in Deep-Sea Hydrothermal Vent Sediments

    DEFF Research Database (Denmark)

    JØRGENSEN, BB; ISAKSEN, MF; JANNASCH, HW

    1992-01-01

    -reducing bacteria was done in hot deep-sea sediments at the hydrothermal vents of the Guaymas Basin tectonic spreading center in the Gulf of California. Radiotracer studies revealed that sulfate reduction can occur at temperatures up to 110-degrees-C, with an optimum rate at 103-degrees to 106-degrees......-C. This observation expands the upper temperature limit of this process in deep-ocean sediments by 20-degrees-C and indicates the existence of an unknown groUp of hyperthermophilic bacteria with a potential importance for the biogeochemistry of sulfur above 100-degrees-C....

  15. Degree and connectivity of the Internet's scale-free topology

    International Nuclear Information System (INIS)

    Zhang Lian-Ming; Wu Xiang-Sheng; Deng Xiao-Heng; Yu Jian-Ping

    2011-01-01

    This paper theoretically and empirically studies the degree and connectivity of the Internet's scale-free topology at an autonomous system (AS) level. The basic features of scale-free networks influence the normalization constant of degree distribution p(k). It develops a new mathematic model for describing the power-law relationships of Internet topology. From this model we theoretically obtain formulas to calculate the average degree, the ratios of the k min -degree (minimum degree) nodes and the k max -degree (maximum degree) nodes, and the fraction of the degrees (or links) in the hands of the richer (top best-connected) nodes. It finds that the average degree is larger for a smaller power-law exponent λ and a larger minimum or maximum degree. The ratio of the k min -degree nodes is larger for larger λ and smaller k min or k max . The ratio of the k max -degree ones is larger for smaller λ and k max or larger k min . The richer nodes hold most of the total degrees of Internet AS-level topology. In addition, it is revealed that the increased rate of the average degree or the ratio of the k min -degree nodes has power-law decay with the increase of k min . The ratio of the k max -degree nodes has a power-law decay with the increase of k max , and the fraction of the degrees in the hands of the richer 27% nodes is about 73% (the ‘73/27 rule’). Finally, empirically calculations are made, based on the empirical data extracted from the Border Gateway Protocol, of the average degree, ratio and fraction using this method and other methods, and find that this method is rigorous and effective for Internet AS-level topology. (interdisciplinary physics and related areas of science and technology)

  16. Training, Degrees, and Credentials in the Hiring of School Psychologists

    Science.gov (United States)

    O'donnell, Patrick S.; Dunlap, Linda L.

    2014-01-01

    A national sample of 246 Directors of Pupil Personnel Services and Directors of Special Education were surveyed to assess the importance they place on training, degrees, and credentials in the hiring of school psychologists. High, but varying, levels of importance were found for the content knowledge and skill areas in the National Association of…

  17. High-Degree Neurons Feed Cortical Computations.

    Directory of Open Access Journals (Sweden)

    Nicholas M Timme

    2016-05-01

    Full Text Available Recent work has shown that functional connectivity among cortical neurons is highly varied, with a small percentage of neurons having many more connections than others. Also, recent theoretical developments now make it possible to quantify how neurons modify information from the connections they receive. Therefore, it is now possible to investigate how information modification, or computation, depends on the number of connections a neuron receives (in-degree or sends out (out-degree. To do this, we recorded the simultaneous spiking activity of hundreds of neurons in cortico-hippocampal slice cultures using a high-density 512-electrode array. This preparation and recording method combination produced large numbers of neurons recorded at temporal and spatial resolutions that are not currently available in any in vivo recording system. We utilized transfer entropy (a well-established method for detecting linear and nonlinear interactions in time series and the partial information decomposition (a powerful, recently developed tool for dissecting multivariate information processing into distinct parts to quantify computation between neurons where information flows converged. We found that computations did not occur equally in all neurons throughout the networks. Surprisingly, neurons that computed large amounts of information tended to receive connections from high out-degree neurons. However, the in-degree of a neuron was not related to the amount of information it computed. To gain insight into these findings, we developed a simple feedforward network model. We found that a degree-modified Hebbian wiring rule best reproduced the pattern of computation and degree correlation results seen in the real data. Interestingly, this rule also maximized signal propagation in the presence of network-wide correlations, suggesting a mechanism by which cortex could deal with common random background input. These are the first results to show that the extent to

  18. Comparative transcriptome and gene co-expression network analysis reveal genes and signaling pathways adaptively responsive to varied adverse stresses in the insect fungal pathogen, Beauveria bassiana.

    Science.gov (United States)

    He, Zhangjiang; Zhao, Xin; Lu, Zhuoyue; Wang, Huifang; Liu, Pengfei; Zeng, Fanqin; Zhang, Yongjun

    2018-01-01

    Sensing, responding, and adapting to the surrounding environment are crucial for all living organisms to survive, proliferate, and differentiate in their biological niches. Beauveria bassiana is an economically important insect-pathogenic fungus which is widely used as a biocontrol agent to control a variety of insect pests. The fungal pathogen unavoidably encounters a variety of adverse environmental stresses and defense response from the host insects during application of the fungal agents. However, few are known about the transcription response of the fungus to respond or adapt varied adverse stresses. Here, we comparatively analyzed the transcriptome of B. bassiana in globe genome under the varied stationary-phase stresses including osmotic agent (0.8 M NaCl), high temperature (32 °C), cell wall-perturbing agent (Congo red), and oxidative agents (H 2 O 2 or menadione). Total of 12,412 reads were obtained, and mapped to the 6767 genes of the B. bassiana. All of these stresses caused transcription responses involved in basal metabolism, cell wall construction, stress response or cell rescue/detoxification, signaling transduction and gene transcription regulation, and likely other cellular processes. An array of genes displayed similar transcription patterns in response to at least two of the five stresses, suggesting a shared transcription response to varied adverse stresses. Gene co-expression network analysis revealed that mTOR signaling pathway, but not HOG1 MAP kinase pathway, played a central role in regulation the varied adverse stress responses, which was verified by RNAi-mediated knockdown of TOR1. Our findings provided an insight of transcription response and gene co-expression network of B. bassiana in adaptation to varied environments. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Psychological factors affecting public acceptance of nuclear energy. Comparative analysis focusing on regional characteristics and degree of knowledge

    International Nuclear Information System (INIS)

    Kimura, Hiroshi; Suzuki, Atsuyuki; Furuta, Kazuo

    2003-01-01

    The purpose of this research is to clarify how psychological factors' impact on public acceptance of nuclear energy varies with where they live and their degree of knowledge. For this purpose, we carried out questionnaire survey about nuclear energy at three urban areas and two nuclear power plant siting areas. After collecting data, we applied factor analysis to the data, and found four factors which construct cognitive structure of nuclear energy. Using multiple regression analysis, we evaluated the impact of the four factors on two issues: the decision for or against nuclear policy and the reaction to nuclear power plant siting, and compared changes of the impact by where respondents live and their degree of knowledge. Consequently, we found that the impact of all four factors on the two issues varies with where respondents live. We also found that the impact of respondents' degree of knowledge to four factors varies with where they live. (author)

  20. Nuclear diffuseness as a degree of freedom

    Science.gov (United States)

    Myers, W. D.; ŚwiaŢecki, W. J.

    1998-12-01

    The response of the nuclear energy to changes in neutron and proton surface diffusenesses is investigated using the Thomas-Fermi model. Algebraic expressions are provided for the energy cost of changing the two diffusenesses away from their equilibrium values. This will make it possible to generalize the macroscopic-microscopic calculations of nuclear masses and deformation energies by the inclusion of the neutron and proton diffusenesses as degrees of freedom (to be varied along with the shape degrees of freedom). One result, which is suggested by the relatively low cost in macroscopic energy of increasing the diffuseness of a heavy nucleus by 10% (about 4 MeV), is that superheavy nuclei near Z=126, N=184 may have a fair chance of becoming stabilized by shell effects. An appendix introduces an improved measure of surface diffuseness, with certain advantages over the conventional Süssmann width b.

  1. Nuclear diffuseness as a degree of freedom

    International Nuclear Information System (INIS)

    Myers, W.D.; Swiatecki, W.J.

    1998-01-01

    The response of the nuclear energy to changes in neutron and proton surface diffusenesses is investigated using the Thomas-Fermi model. Algebraic expressions are provided for the energy cost of changing the two diffusenesses away from their equilibrium values. This will make it possible to generalize the macroscopic-microscopic calculations of nuclear masses and deformation energies by the inclusion of the neutron and proton diffusenesses as degrees of freedom (to be varied along with the shape degrees of freedom). One result, which is suggested by the relatively low cost in macroscopic energy of increasing the diffuseness of a heavy nucleus by 10% (about 4 MeV), is that superheavy nuclei near Z=126, N=184 may have a fair chance of becoming stabilized by shell effects. An appendix introduces an improved measure of surface diffuseness, with certain advantages over the conventional Suessmann width b. copyright 1998 The American Physical Society

  2. Bioglass implant-coating interactions in synthetic physiological fluids with varying degrees of biomimicry.

    Science.gov (United States)

    Popa, A C; Stan, G E; Husanu, M A; Mercioniu, I; Santos, L F; Fernandes, H R; Ferreira, Jmf

    2017-01-01

    Synthetic physiological fluids are currently used as a first in vitro bioactivity assessment for bone grafts. Our understanding about the interactions taking place at the fluid-implant interface has evolved remarkably during the last decade, and does not comply with the traditional International Organization for Standardization/final draft International Standard 23317 protocol in purely inorganic simulated body fluid. The advances in our knowledge point to the need of a true paradigm shift toward testing physiological fluids with enhanced biomimicry and a better understanding of the materials' structure-dissolution behavior. This will contribute to "upgrade" our vision of entire cascades of events taking place at the implant surfaces upon immersion in the testing media or after implantation. Starting from an osteoinductive bioglass composition with the ability to alleviate the oxidative stress, thin bioglass films with different degrees of polymerization were deposited onto titanium substrates. Their biomineralization activity in simulated body fluid and in a series of new inorganic-organic media with increasing biomimicry that more closely simulated the human intercellular environment was compared. A comprehensive range of advanced characterization tools (scanning electron microscopy; grazing-incidence X-ray diffraction; Fourier-transform infrared, micro-Raman, energy-dispersive, X-ray photoelectron, and surface-enhanced laser desorption/ionization time-of-flight mass spectroscopies; and cytocompatibility assays using mesenchymal stem cells) were used. The information gathered is very useful to biologists, biophysicists, clinicians, and material scientists with special interest in teaching and research. By combining all the analyses, we propose herein a step forward toward establishing an improved unified protocol for testing the bioactivity of implant materials.

  3. Educational Attainment and Financial Satisfaction: The Changing Economic Value of a College Degree

    Science.gov (United States)

    Menard, Lauren Ann

    2014-01-01

    Dwindling American financial satisfaction and growing college degree attainment were revealed in national social survey data spanning more than four decades (N = 57,061). Against these backdrops, associations between being financially satisfied and having a college degree grew stronger in each decade, with the strongest association between…

  4. Persistence of Women in Online Degree-Completion Programs

    Directory of Open Access Journals (Sweden)

    Terry Müller

    2008-06-01

    Full Text Available Although online courses at postsecondary institutions promise adults access, flexibility, and convenience, many barriers to online learning remain. This article presents findings from a qualitative case study, which explored the phenomenon of undergraduate and graduate women learners’ persistence in online degree-completion programs at a college in the Northeast of the United States. Research questions asked why women learners persisted or failed to persist, and how factors supporting or hindering persistence influenced learners. Interviews with a purposeful sample of 20 participants revealed the complexity of variables affecting learners’ persistence to graduation. Findings suggested that multiple responsibilities, insufficient interaction with faculty, technology, and coursework ranked highest as barriers to women’s persistence. Strong motivation to complete degrees, engagement in the learning community, and appreciation for the convenience of an online degree-completion option facilitated persistence.

  5. Annelid Distal-less/Dlx duplications reveal varied post-duplication fates

    Directory of Open Access Journals (Sweden)

    Korchagina Natalia

    2011-08-01

    Full Text Available Abstract Background Dlx (Distal-less genes have various developmental roles and are widespread throughout the animal kingdom, usually occurring as single copy genes in non-chordates and as multiple copies in most chordate genomes. While the genomic arrangement and function of these genes is well known in vertebrates and arthropods, information about Dlx genes in other organisms is scarce. We investigate the presence of Dlx genes in several annelid species and examine Dlx gene expression in the polychaete Pomatoceros lamarckii. Results Two Dlx genes are present in P. lamarckii, Capitella teleta and Helobdella robusta. The C. teleta Dlx genes are closely linked in an inverted tail-to-tail orientation, reminiscent of the arrangement of vertebrate Dlx pairs, and gene conversion appears to have had a role in their evolution. The H. robusta Dlx genes, however, are not on the same genomic scaffold and display divergent sequences, while, if the P. lamarckii genes are linked in a tail-to-tail orientation they are a minimum of 41 kilobases apart and show no sign of gene conversion. No expression in P. lamarckii appendage development has been observed, which conflicts with the supposed conserved role of these genes in animal appendage development. These Dlx duplications do not appear to be annelid-wide, as the polychaete Platynereis dumerilii likely possesses only one Dlx gene. Conclusions On the basis of the currently accepted annelid phylogeny, we hypothesise that one Dlx duplication occurred in the annelid lineage after the divergence of P. dumerilii from the other lineages and these duplicates then had varied evolutionary fates in different species. We also propose that the ancestral role of Dlx genes is not related to appendage development.

  6. Case Study: Creation of a Degree Program in Computer Security. White Paper.

    Science.gov (United States)

    Belon, Barbara; Wright, Marie

    This paper reports on research into the field of computer security, and undergraduate degrees offered in that field. Research described in the paper reveals only one computer security program at the associate's degree level in the entire country. That program, at Texas State Technical College in Waco, is a 71-credit-hour program leading to an…

  7. Psychology Degrees: Employment, Wage, and Career Trajectory Consequences.

    Science.gov (United States)

    Rajecki, D W; Borden, Victor M H

    2011-07-01

    Psychology is a very popular undergraduate major. Examining wage data from a range of degree holders reveals much about the expected career trajectories of those with psychology degrees. First, regarding baccalaureates, psychology and other liberal arts graduates-compared with those from certain preprofessional and technical undergraduate programs-generally fall in relatively low tiers of salary levels at both starting and later career points. Salary levels among baccalaureate alumni groups correlate with averaged measures of salary satisfaction, repeated job seeking, and perceptions of underemployment. These patterns seem to stem from the specific occupational categories (job titles) entered by graduates in psychology compared with other graduates, calling into question the employability advantage of so-called generic liberal arts skills. Second, psychology master's degree holders also generally fall in a low tier of salary among their science, engineering, and health counterparts. Third, psychology college faculty (including instructors) fall in low tiers of salary compared with their colleagues from other academic fields. Such broadly based indications of the relative economic disadvantages of psychology degrees have implications for career counseling in the field. © The Author(s) 2011.

  8. Magnetic field control of 90 Degree-Sign , 180 Degree-Sign , and 360 Degree-Sign domain wall resistance

    Energy Technology Data Exchange (ETDEWEB)

    Majidi, Roya, E-mail: royamajidi@gmail.com [Department of Physics, Shahid Rajaee Teacher Training University, Lavizan, 16788-15811 Tehran (Iran, Islamic Republic of)

    2012-10-01

    In the present work, we have compared the resistance of the 90 Degree-Sign , 180 Degree-Sign , and 360 Degree-Sign domain walls in the presence of external magnetic field. The calculations are based on the Boltzmann transport equation within the relaxation time approximation. One-dimensional Neel-type domain walls between two domains whose magnetization differs by angle of 90 Degree-Sign , 180 Degree-Sign , and 360 Degree-Sign are considered. The results indicate that the resistance of the 360 Degree-Sign DW is more considerable than that of the 90 Degree-Sign and 180 Degree-Sign DWs. It is also found that the domain wall resistance can be controlled by applying transverse magnetic field. Increasing the strength of the external magnetic field enhances the domain wall resistance. In providing spintronic devices based on magnetic nanomaterials, considering and controlling the effect of domain wall on resistivity are essential.

  9. Fourier decomposition of spatial localization errors reveals an idiotropic dominance of an internal model of gravity.

    Science.gov (United States)

    De Sá Teixeira, Nuno Alexandre

    2014-12-01

    Given its conspicuous nature, gravity has been acknowledged by several research lines as a prime factor in structuring the spatial perception of one's environment. One such line of enquiry has focused on errors in spatial localization aimed at the vanishing location of moving objects - it has been systematically reported that humans mislocalize spatial positions forward, in the direction of motion (representational momentum) and downward in the direction of gravity (representational gravity). Moreover, spatial localization errors were found to evolve dynamically with time in a pattern congruent with an anticipated trajectory (representational trajectory). The present study attempts to ascertain the degree to which vestibular information plays a role in these phenomena. Human observers performed a spatial localization task while tilted to varying degrees and referring to the vanishing locations of targets moving along several directions. A Fourier decomposition of the obtained spatial localization errors revealed that although spatial errors were increased "downward" mainly along the body's longitudinal axis (idiotropic dominance), the degree of misalignment between the latter and physical gravity modulated the time course of the localization responses. This pattern is surmised to reflect increased uncertainty about the internal model when faced with conflicting cues regarding the perceived "downward" direction.

  10. Attenuation of the Squared Canonical Correlation Coefficient under Varying Estimates of Score Reliability

    Science.gov (United States)

    Wilson, Celia M.

    2010-01-01

    Research pertaining to the distortion of the squared canonical correlation coefficient has traditionally been limited to the effects of sampling error and associated correction formulas. The purpose of this study was to compare the degree of attenuation of the squared canonical correlation coefficient under varying conditions of score reliability.…

  11. Relationship between lignin structure and delignification degree in Pinus pinaster kraft pulps.

    Science.gov (United States)

    Baptista, C; Robert, D; Duarte, A P

    2008-05-01

    This study examines the structure of residual and dissolved lignins from Pinus pinaster pulps obtained at different degrees of delignification by laboratory conventional kraft pulping. The cooking H factor was varied from 85 to 8049. The residual and dissolved lignin samples were characterised by elemental analysis, residual carbohydrate content, permanganate oxidation and 13C NMR spectroscopy. The reflectance factor of the pulps was also determined in order to tentatively correlate the delignification degree and residual lignin structure with the pulp colour. The obtained results confirmed that the delignification degree increases the condensation of the lignin structure, which might have an influence upon the observed increased pulp colour. The lack of selectivity of kraft pulping process in the case of more delignified pulps was also shown.

  12. Negative Impact of Employment on Engineering Student Time Management, Time to Degree, and Retention: Faculty, Administrator, and Staff Perspectives

    Science.gov (United States)

    Tyson, Will

    2012-01-01

    Interviews with faculty, administrators, staff, and students at four engineering programs reveal the role of undergraduate student employment on retention and timely degree completion among engineering students. Dueling narratives reveal how student approaches to earning an engineering degree differ greatly from faculty, administrator, and staff…

  13. The system Cu-Rh-S at 900 degrees, 700 degrees, 540 degrees and 500 degrees C

    DEFF Research Database (Denmark)

    Karup-Møller, Sven; Makovicky, E.

    2007-01-01

    Phase relations in the dry condensed system Cu-Rh-S were determined at 900, 700, 540 and 500 degrees C. At 900 degrees C, the system contains digenite, four rhodium sulfides (Rh17S15, Rh3S4, Rh2S3 and RhS similar to 3), three ternary sulfides (CuRh2S4, CuxRhS3+x and a fibrous sulfide in the range...

  14. A compensation controller based on a regional pole-assignment method for AMD control systems with a time-varying delay

    Science.gov (United States)

    Li, Zuohua; Chen, Chaojun; Teng, Jun; Wang, Ying

    2018-04-01

    Active mass damper/driver (AMD) control system has been proposed as an effective tool for high-rise buildings to resist strong dynamic loads. However, such disadvantage as time-varying delay in AMD control systems impedes their application in practices. Time-varying delay, which has an effect on the performance and stability of single-degree-of-freedom (SDOF) and multi-degree-of-freedom (MDOF) systems, is considered in the paper. In addition, a new time-delay compensation controller based on regional pole-assignment method is presented. To verify its effectiveness, the proposed method is applied to a numerical example of a ten-storey frame and an experiment of a single span four-storey steel frame. Both numerical and experimental results demonstrate that the proposed method can enhance the performances of an AMD control system with time-varying delays.

  15. Tensile properties of vanadium alloys irradiated at <430{degrees}C

    Energy Technology Data Exchange (ETDEWEB)

    Chung, H.M.; Smith, D.L. [Argonne National Lab., IL (United States)

    1997-08-01

    Recent attention to vanadium alloys has focused on significant susceptibility to loss of work-hardening capability in irradiation experiments at <430{degrees}C. An evaluation of this phenomenon was conducted on V-Ti, V-Cr-Ti, and V-Ti-Si alloys irradiated in several conventional and helium-charging irradiation experiments in the FFTF-MOTA, HFIR, and EBR-II. Work hardening capability and uniform tensile elongation appear to vary strongly from alloy and heat to heat. A strong heat-to-heat variation has been observed in V-4Cr-4Ti alloys tested, i.e., a 500-kg heat (No. 832665), a 100-kg heat (VX-8), and a 30-kg heat (BL-47). The significant differences in susceptibility to loss of work-hardening capability from one heat to another are estimated to correspond to a difference of {approx}100{degrees}C or more in minimum allowable operating temperature (e.g., 450 versus 350{degrees}C).

  16. Comparative analyses of six solanaceous transcriptomes reveal a high degree of sequence conservation and species-specific transcripts

    Directory of Open Access Journals (Sweden)

    Ouyang Shu

    2005-09-01

    Full Text Available Abstract Background The Solanaceae is a family of closely related species with diverse phenotypes that have been exploited for agronomic purposes. Previous studies involving a small number of genes suggested sequence conservation across the Solanaceae. The availability of large collections of Expressed Sequence Tags (ESTs for the Solanaceae now provides the opportunity to assess sequence conservation and divergence on a genomic scale. Results All available ESTs and Expressed Transcripts (ETs, 449,224 sequences for six Solanaceae species (potato, tomato, pepper, petunia, tobacco and Nicotiana benthamiana, were clustered and assembled into gene indices. Examination of gene ontologies revealed that the transcripts within the gene indices encode a similar suite of biological processes. Although the ESTs and ETs were derived from a variety of tissues, 55–81% of the sequences had significant similarity at the nucleotide level with sequences among the six species. Putative orthologs could be identified for 28–58% of the sequences. This high degree of sequence conservation was supported by expression profiling using heterologous hybridizations to potato cDNA arrays that showed similar expression patterns in mature leaves for all six solanaceous species. 16–19% of the transcripts within the six Solanaceae gene indices did not have matches among Solanaceae, Arabidopsis, rice or 21 other plant gene indices. Conclusion Results from this genome scale analysis confirmed a high level of sequence conservation at the nucleotide level of the coding sequence among Solanaceae. Additionally, the results indicated that part of the Solanaceae transcriptome is likely to be unique for each species.

  17. Scattering of particles with internal degrees of freedom

    International Nuclear Information System (INIS)

    Slipushenko, S. V.; Tur, A. V.; Yanovsky, V. V.

    2013-01-01

    The scattering of particles with a small number of internal degrees of freedom is considered. Billiard formalism is used to study the scattering of two such structurally complex particles. The main scattering characteristics are found. Various types of scattering modes are revealed. In particular, a mode is detected when the velocity of motion of such particles away from each other is higher than their approach velocity before the collision. The scattering of such particles is shown to occur after a finite number of collisions. A generalized Newton law is proposed for the collision of particles with a small number of degrees of freedom, and the form of the effective coefficient of restitution is found

  18. When Graduate Degrees Prostitute the Educational Process: Degrees Gone Wild

    Science.gov (United States)

    Lumadue, Richard T.

    2006-01-01

    Graduate degrees prostitute the educational process when they are sold to consumers by unaccredited degree/diploma mills as being equivalent to legitimate, bona-fide degrees awarded by accredited graduate schools. This article carefully analyzes the serious problems of bogus degrees and their association with the religious higher education…

  19. Timely Post-Graduate Degree Completion: A Case Study of Jamshoro Education City

    Directory of Open Access Journals (Sweden)

    Jagul Huma Lashari

    2013-01-01

    Full Text Available This study identifies the status of postgraduate students at the master degree level regarding their degree completion in the three public sector universities at Jamshoro Education City. The status is identified by analyzing enrolment of the postgraduate and comparing it with rate of their degree completion. In addition, the paper also discusses their characteristics which lead them towards the degree completion. For this paper, enrolment of the postgraduate students at the master level is compared with the degree completion rate of 2008 academic session only. The result shows the obvious difference between enrolment and rate of the degree completion. In total 417 postgraduate students were enrolled in 2008 session, however, only 60 (14% of students have completed their postgraduate degrees. Those who have completed their degrees, with respect to universities 6% students belong to US (University of Sindh, 22% belong to MUET (Mehran University of Engineering & Technology and 8% students belong to LUMHS (Liaquat University of Medical & Health Sciences. The demographical data of the postgraduate students has also shown some variations like gender, age, employment, and financial resources. In addition, the research requirements also vary for different postgraduate students. The research requirements include lab based, field based and library based resources. The characteristics of the postgraduate students of three public sector universities including financial resources, employment status, and working organization also show differences with each-other in terms of the degree completion.

  20. Biochemical parameters in the blood of grass snakes (Natrix natrix in ecosystems under varying degrees of anthropogenic influence

    Directory of Open Access Journals (Sweden)

    V. Y. Gasso

    2016-09-01

    Full Text Available The grass snake Natrix natrix (Linnaeus, 1758 is a partly hygrophilous species, distributed throughoutUkraine. This snake may be considered as a test object for environmental biomonitoring. Modern biochemical methods make it possible to obtain new scientific data on the effects of anthropogenic pressure on reptiles. Blood is a sensitive and informative indicator of the condition of an organism as it responds quickly to most changes in exogenous and endogenous factors, and reflects negative influences on both individual and, indirectly, populations. Changes in biochemical parameters may be used as biomarkers of the state of health of reptiles in ecosystems under varying degrees of anthropogenic pressure. Due the increase in anthropogenic influence the development and introduction of new methods of perceptual research, collection of up-to-date information and development of a database of reptile biochemical parameters have become an urgent priority. We collected mature individuals of the grass snake in floodplain ecosystems on the right bank of the Dnieper River in Dnipropetrovsk city. Grass snakes from floodplain habitats on the left bank of theSamaraRiver (O.L. Belgard Prysamarskii International Biosphere Station, Novomoskovsk district, Dnipropetrovsk province were studied as the control specimens. Our study demonstrated statistically significant differences between snakes from the study sites in the amount of albumin, urea and urea nitrogen, and inorganic phosphorus, as well as in alanine aminotransferase (ALT and alkaline phosphatise (AP activity. The amount of albumin in the blood serum of specimens from the anthropogenically transformed areas was significantly lower (by 25% than in that of the snakes caught in the control habitats. Decrease of the albumin concentration usually indicates abnormal processes in the kidneys and liver. According to the changes observed in the concentration of albumin, a corresponding increase in the albumin to

  1. Presbycusis phenotypes form a heterogeneous continuum when ordered by degree and configuration of hearing loss.

    Science.gov (United States)

    Allen, Paul D; Eddins, David A

    2010-06-01

    Many reports have documented age-by-frequency increases in average auditory thresholds in various human populations. Despite this, the prevalence of different patterns of hearing loss in presbycusis remains uncertain. We examined 'presbycusis phenotypes' in a database of 960 subjects (552 female, 408 male, 18-92 years) that each had 30 measures of peripheral hearing sensitivity: pure tone audiograms for left and right ears from 0.25 to 8 kHz and DPOAE for each ear with F(mean)=1-6.4 kHz. Surprisingly, the hearing phenotypes did not naturally separate into discrete classes of presbycusis. Principal component (PC) analysis revealed that two principal components account for 74% of the variance among the 30 measures of hearing. The two components represent the overall degree (PC1) and configuration of loss (Flat vs. Sloping; PC2) and the phenotypes form a continuum when plotted against them. A heuristic partitioning of this continuum produced classes of presbycusis that vary in their degree of Sloping or Flat hearing loss, suggesting that the previously reported sub-types of presbycusis arise from the categorical segregation of a continuous and heterogeneous distribution. Further, most phenotypes lie intermediate to the extremes of either Flat or Sloping loss, indicating that if audiometric configuration does predict presbycusis etiology, then a mixed origin is the most prevalent. Copyright 2010 Elsevier B.V. All rights reserved.

  2. Second-degree discrete Painleve equations conceal first-degree ones

    International Nuclear Information System (INIS)

    Ramani, A; Grammaticos, B; Joshi, N

    2010-01-01

    We examine various second-degree difference equations which have been proposed over the years and according to their authors' claims should be integrable. This study is motivated by the fact that we consider that second-degree discrete systems cannot be integrable due to the proliferation of the images (and pre-images) of the initial point. We show that in the present cases no contradiction exists. In all cases examined, we show that there exists an underlying integrable first-degree mapping which allows us to obtain an appropriate solution of the second-degree one.

  3. Validation and genotyping of multiple human polymorphic inversions mediated by inverted repeats reveals a high degree of recurrence.

    Directory of Open Access Journals (Sweden)

    Cristina Aguado

    2014-03-01

    Full Text Available In recent years different types of structural variants (SVs have been discovered in the human genome and their functional impact has become increasingly clear. Inversions, however, are poorly characterized and more difficult to study, especially those mediated by inverted repeats or segmental duplications. Here, we describe the results of a simple and fast inverse PCR (iPCR protocol for high-throughput genotyping of a wide variety of inversions using a small amount of DNA. In particular, we analyzed 22 inversions predicted in humans ranging from 5.1 kb to 226 kb and mediated by inverted repeat sequences of 1.6-24 kb. First, we validated 17 of the 22 inversions in a panel of nine HapMap individuals from different populations, and we genotyped them in 68 additional individuals of European origin, with correct genetic transmission in ∼ 12 mother-father-child trios. Global inversion minor allele frequency varied between 1% and 49% and inversion genotypes were consistent with Hardy-Weinberg equilibrium. By analyzing the nucleotide variation and the haplotypes in these regions, we found that only four inversions have linked tag-SNPs and that in many cases there are multiple shared SNPs between standard and inverted chromosomes, suggesting an unexpected high degree of inversion recurrence during human evolution. iPCR was also used to check 16 of these inversions in four chimpanzees and two gorillas, and 10 showed both orientations either within or between species, providing additional support for their multiple origin. Finally, we have identified several inversions that include genes in the inverted or breakpoint regions, and at least one disrupts a potential coding gene. Thus, these results represent a significant advance in our understanding of inversion polymorphism in human populations and challenge the common view of a single origin of inversions, with important implications for inversion analysis in SNP-based studies.

  4. Bioglass implant-coating interactions in synthetic physiological fluids with varying degrees of biomimicry

    Directory of Open Access Journals (Sweden)

    Popa AC

    2017-01-01

    Full Text Available AC Popa,1,2 GE Stan,1 MA Husanu,1 I Mercioniu,1 LF Santos,3 HR Fernandes,4 JMF Ferreira4 1National Institute of Materials Physics, Măgurele, 2Army Centre for Medical Research, Bucharest, Romania; 3Centro de Química Estrutural, Instituto Superior Técnico (CQE-IST, University of Lisbon, Lisbon, 4Department of Materials and Ceramics Engineering, Centre for Research in Ceramics and Composite Materials (CICECO, University of Aveiro, Aveiro, Portugal Abstract: Synthetic physiological fluids are currently used as a first in vitro bioactivity assessment for bone grafts. Our understanding about the interactions taking place at the fluid–implant interface has evolved remarkably during the last decade, and does not comply with the traditional International Organization for Standardization/final draft International Standard 23317 protocol in purely inorganic simulated body fluid. The advances in our knowledge point to the need of a true paradigm shift toward testing physiological fluids with enhanced biomimicry and a better understanding of the materials’ structure-dissolution behavior. This will contribute to “upgrade” our vision of entire cascades of events taking place at the implant surfaces upon immersion in the testing media or after implantation. Starting from an osteoinductive bioglass composition with the ability to alleviate the oxidative stress, thin bioglass films with different degrees of polymerization were deposited onto titanium substrates. Their bio­mineralization activity in simulated body fluid and in a series of new inorganic–organic media with increasing biomimicry that more closely simulated the human intercellular environment was compared. A comprehensive range of advanced characterization tools (scanning electron microscopy; grazing-incidence X-ray diffraction; Fourier-transform infrared, micro-Raman, energy-dispersive, X-ray photoelectron, and surface-enhanced laser desorption/ionization time-of-flight mass

  5. Heterocyclic amine content in beef cooked by different methods to varying degrees of doneness and gravy made from meat drippings.

    Science.gov (United States)

    Sinha, R; Rothman, N; Salmon, C P; Knize, M G; Brown, E D; Swanson, C A; Rhodes, D; Rossi, S; Felton, J S; Levander, O A

    1998-04-01

    Meats cooked at high temperatures sometimes contain heterocyclic amines (HCAs) that are known mutagens and animal carcinogens, but their carcinogenic potential in humans has not been established. To investigate the association between HCAs and cancer, sources of exposure to these compounds need to be determined. Beef is the most frequently consumed meat in the United States and for this study we determined HCA values in beef samples cooked in ways to represent US cooking practices, the results of which can be used in epidemiological studies to estimate HCA exposure from dietary questionnaires. We measured five HCAs [2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ), 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline (DiMeIQx) and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)] in different types of cooked beef using solid-phase extraction and HPLC. Steak and hamburger patties were pan-fried, oven-broiled, and grilled/barbecued to four levels of doneness (rare, medium, well done or very well done), while beef roasts were oven cooked to three levels of doneness (rare, medium or well done). The measured values of the specific HCAs varied with the cut of beef, cooking method, and doneness level. In general, MeIQx content increased with doneness under each cooking condition for steak and hamburger patties, up to 8.2 ng/g. PhIP was the predominant HCA produced in steak (1.9 to 30 ng/g), but was formed only in very well done fried or grilled hamburger. DiMeIQx was found in trace levels in pan-fried steaks only, while IQ and MeIQ were not detectable in any of the samples. Roast beef did not contain any of the HCAs, but the gravy made from the drippings from well done roasts had 2 ng/g of PhIP and 7 ng/g of MeIQx. Epidemiological studies need to consider the type of meat, cooking method and degree of doneness/surface browning in survey questions to adequately assess

  6. The Degree of Court's Control on Arbitration under the Ethiopian Law

    African Journals Online (AJOL)

    The Degree of Court's Control on Arbitration under the Ethiopian Law: Is It to the ... C)) reveals that courts in Ethiopia control arbitration by such avenues as appeal, ... all overlook the avenue of refusal, particularly in terms of domestic awards.

  7. Why Do English Universities "Really" Franchise Degrees to Overseas Providers?

    Science.gov (United States)

    Healey, Nigel

    2013-01-01

    Franchising degrees to overseas providers, normally for-profit private companies, has become big business for English universities. The latest data from the Higher Education Statistics Agency reveal that there are now more international students registered for the awards of English higher education institutions that are studying wholly offshore…

  8. Reflux and Belching After 270 Degree Versus 360 Degree Laparoscopic Posterior Fundoplication

    NARCIS (Netherlands)

    Broeders, Joris A.; Bredenoord, Albert J.; Hazebroek, Eric J.; Broeders, Ivo A.; Gooszen, Hein G.; Smout, André J.

    2012-01-01

    Objective: To investigate differences in effects of 270 degrees (270 degrees LPF) and 360 degrees laparoscopic posterior fundoplication (360 degrees LPF) on reflux characteristics and belching. Background: Three hundred sixty degrees LPF greatly reduces the ability of the stomach to vent ingested

  9. Current Trends in Communication Graduate Degrees: Survey of Communications, Advertising, PR, and IMC Graduate Programs

    Science.gov (United States)

    Quesenberry, Keith A.; Coolsen, Michael K.; Wilkerson, Kristen

    2015-01-01

    A survey of 61 master's degree advertising programs reveals significant trends in program titles, curriculum design, course delivery, and students served. The results provide insight for current and planned master's degree programs as research predicts a continued increase in demand for master's education over the next decade. Survey results are…

  10. An integrative time-varying frequency detection and channel sounding method for dynamic plasma sheath

    Science.gov (United States)

    Shi, Lei; Yao, Bo; Zhao, Lei; Liu, Xiaotong; Yang, Min; Liu, Yanming

    2018-01-01

    The plasma sheath-surrounded hypersonic vehicle is a dynamic and time-varying medium and it is almost impossible to calculate time-varying physical parameters directly. The in-fight detection of the time-varying degree is important to understand the dynamic nature of the physical parameters and their effect on re-entry communication. In this paper, a constant envelope zero autocorrelation (CAZAC) sequence based on time-varying frequency detection and channel sounding method is proposed to detect the plasma sheath electronic density time-varying property and wireless channel characteristic. The proposed method utilizes the CAZAC sequence, which has excellent autocorrelation and spread gain characteristics, to realize dynamic time-varying detection/channel sounding under low signal-to-noise ratio in the plasma sheath environment. Theoretical simulation under a typical time-varying radio channel shows that the proposed method is capable of detecting time-variation frequency up to 200 kHz and can trace the channel amplitude and phase in the time domain well under -10 dB. Experimental results conducted in the RF modulation discharge plasma device verified the time variation detection ability in practical dynamic plasma sheath. Meanwhile, nonlinear phenomenon of dynamic plasma sheath on communication signal is observed thorough channel sounding result.

  11. Development of a medical academic degree system in China.

    Science.gov (United States)

    Wu, Lijuan; Wang, Youxin; Peng, Xiaoxia; Song, Manshu; Guo, Xiuhua; Nelson, Hugh; Wang, Wei

    2014-01-01

    The Chinese government launched a comprehensive healthcare reform to tackle challenges to health equities. Medical education will become the key for successful healthcare reform. We describe the current status of the Chinese medical degree system and its evolution over the last 80 years. Progress has been uneven, historically punctuated most dramatically by the Cultural Revolution. There is a great regional disparity. Doctors with limited tertiary education may be licensed to practice, whereas medical graduates with advanced doctorates may have limited clinical skills. There are undefined relationships between competing tertiary training streams, the academic professional degree, and the clinical residency training programme (RTP). The perceived quality of training in both streams varies widely across China. As the degrees of master or doctor of academic medicine is seen as instrumental in career advancement, including employability in urban hospitals, attainment of this degree is sought after, yet is often unrelated to a role in health care, or is seen as superior to clinical experience. Meanwhile, the practical experience gained in some prestigious academic institutions is deprecated by the RTP and must be repeated before accreditation for clinical practice. This complexity is confusing both for students seeking the most appropriate training, and also for clinics, hospitals and universities seeking to recruit the most appropriate applicants. The future education reforms might include: 1) a domestic system of 'credits' that gives weight to quality clinical experience vs. academic publications in career advancement, enhanced harmonisation between the competing streams of the professional degree and the RTP, and promotion of mobility of staff between areas of excellence and areas of need; 2) International - a mutual professional and academic recognition between China and other countries by reference to the Bologna Accord, setting up a system of easily comparable and

  12. Physics & Astronomy Master's Initial Employment: Data from the Degree Recipient Follow-Up Survey for the Classes of 2006, 2007 and 2008. Focus On

    Science.gov (United States)

    Mulvey, Patrick; Shindel, Brandon

    2011-01-01

    This report presents the characteristics and initial outcomes of exiting master's degree recipients in physics and astronomy. The report covers the degree classes of 2006, 2007 and 2008. The status of exiting physics master's varied greatly by the citizenship of the degree recipient. The majority of US citizens entered or remained in the workforce…

  13. Multi-pulse chaotic motions of a rotor-active magnetic bearing system with time-varying stiffness

    International Nuclear Information System (INIS)

    Zhang, W.; Yao, M.H.; Zhan, X.P.

    2006-01-01

    In this paper, we investigate the Shilnikov type multi-pulse chaotic dynamics for a rotor-active magnetic bearings (AMB) system with 8-pole legs and the time-varying stiffness. The stiffness in the AMB is considered as the time-varying in a periodic form. The dimensionless equation of motion for the rotor-AMB system with the time-varying stiffness in the horizontal and vertical directions is a two-degree-of-freedom nonlinear system with quadratic and cubic nonlinearities and parametric excitation. The asymptotic perturbation method is used to obtain the averaged equations in the case of primary parametric resonance and 1/2 subharmonic resonance. It is found from the numerical results that there are the phenomena of the Shilnikov type multi-pulse chaotic motions for the rotor-AMB system. A new jumping phenomenon is discovered in the rotor-AMB system with the time-varying stiffness

  14. Providing Homeless Adults with Advantage: A Sustainable University Degree Program

    Science.gov (United States)

    Sinatra, Richard; Lanctot, Melissa Kim

    2016-01-01

    A university partnered with the New York City Department of Homeless Services (NYC DHS) to provide cohorts of adults a 60-credit Associate Degree Program in Business Administration over a 2-year period. Results of two cohorts of 30 Advantage Academy Program graduates revealed significant improvement in College Board AccuPlacer (ACPL) Arithmetic…

  15. Label Propagation with α-Degree Neighborhood Impact for Network Community Detection

    Directory of Open Access Journals (Sweden)

    Heli Sun

    2014-01-01

    Full Text Available Community detection is an important task for mining the structure and function of complex networks. In this paper, a novel label propagation approach with α-degree neighborhood impact is proposed for efficiently and effectively detecting communities in networks. Firstly, we calculate the neighborhood impact of each node in a network within the scope of its α-degree neighborhood network by using an iterative approach. To mitigate the problems of visiting order correlation and convergence difficulty when updating the node labels asynchronously, our method updates the labels in an ascending order on the α-degree neighborhood impact of all the nodes. The α-degree neighborhood impact is also taken as the updating weight value, where the parameter impact scope α can be set to a positive integer. Experimental results from several real-world and synthetic networks show that our method can reveal the community structure in networks rapidly and accurately. The performance of our method is better than other label propagation based methods.

  16. Evaluation of the degree of dispersion of organoclay on nanocomposites with PP/EPDM

    International Nuclear Information System (INIS)

    Braga, F.C.F.; Oliveira, M.G.

    2010-01-01

    Nanocomposites of thermoplastic elastomer (TPE) composed by PP/EPDM 1/1 blend and organoclay were obtained by the melt intercalation in an internal chamber mix. Initially, a masterbatch of maleinized polypropylene (PP-MA) and clay modified with alkyl ammonium salt in the ratio 3:1 was prepared, and then, added to TPE matrix to obtain loads of 2,5; 5 and 7 wt% of clay in the nanocomposite. The dispersion degree of clay in TPE matrix was evaluated by X-ray diffraction and parallel plate rheometry. The intercalation/exfoliate degree or the degree of dispersion varied with clay content, as observed by X-ray diffraction. This behavior was confirmed by the profile of the curves of elastic modulus versus frequency, which presented different slopes in the region of low frequency, due to the presence of clay and PP-MA. (author)

  17. Wage Returns to University Disciplines in Greece: Are Greek Higher Education Degrees Trojan Horses?

    Science.gov (United States)

    Livanos, Ilias; Pouliakas, Konstantinos

    2011-01-01

    This paper examines the wage returns to qualifications and academic disciplines in the Greek labour market. Exploring wage responsiveness across various degree subjects in Greece is interesting, as it is characterised by high levels of graduate unemployment, which vary considerably with the field of study, and relatively low levels of wage…

  18. The Degree Cycle

    DEFF Research Database (Denmark)

    Wood, Johanna

    2016-01-01

    , empirical data relevant to the development of the degree adverb function is presented and possible relevant constructions identified. It is argued that the degree adverb function of that possibly occurs later than the historical dictionaries indicate. The degree adverb function of this is challenging...

  19. Estimation of Time-Varying Coherence and Its Application in Understanding Brain Functional Connectivity

    Directory of Open Access Journals (Sweden)

    Cheng Liu

    2010-01-01

    Full Text Available Time-varying coherence is a powerful tool for revealing functional dynamics between different regions in the brain. In this paper, we address ways of estimating evolutionary spectrum and coherence using the general Cohen's class distributions. We show that the intimate connection between the Cohen's class-based spectra and the evolutionary spectra defined on the locally stationary time series can be linked by the kernel functions of the Cohen's class distributions. The time-varying spectra and coherence are further generalized with the Stockwell transform, a multiscale time-frequency representation. The Stockwell measures can be studied in the framework of the Cohen's class distributions with a generalized frequency-dependent kernel function. A magnetoencephalography study using the Stockwell coherence reveals an interesting temporal interaction between contralateral and ipsilateral motor cortices under the multisource interference task.

  20. Estimation of thermal sensation during varied air temperature conditions.

    Science.gov (United States)

    Katsuura, T; Tabuchi, R; Iwanaga, K; Harada, H; Kikuchi, Y

    1998-03-01

    Seven male students were exposed to four varied air temperature environments: hot (37 degrees C) to neutral (27 degrees C) (HN), neutral to hot (NH), cool (17 degrees C) to neutral (CN), and neutral to cool (NC). The air temperature was maintained at the first condition for 20 min, then was changed to the second condition after 15 min and was held there for 20 min. Each subject wore a T-shirt, briefs, trunks, and socks. Each sat on a chair and was continuously evaluated for thermal sensation, thermal comfort, and air velocity sensation. Some physiological and thermal parameters were also measured every 5 s during the experiment. The correlation between thermal sensation and skin temperature at 15 sites was found to be poor. The subjects felt much warmer during the rising phase of the air temperature (CN, NH) than during the descending phase (HN, NC) at a given mean skin temperature. However, thermal sensation at the same heat flux or at the same value of the difference between skin and air temperature (delta(Tsk - Ta)) was not so different among the four experimental conditions, and the correlation between thermal sensation and heat flux or delta(Tsk - Ta) was fairly good. The multiple regression equation of the thermal sensation (TS) on 15 sites of skin temperature (Tsk; degrees C) was calculated and the coefficient of determination (R*2) was found to be 0.656. Higher coefficients of determination were found in the equations of thermal sensation for the heat flux (H; kcal.m-2.h-1) at the right and left thighs of the subjects and on delta(Tsk - Ta) (degrees C) at 4 sites. They were as follows: TS = 2.04 - 0.016 Hright - 0.036 Hleft; R*2 = 0.717, TS = 1.649 + 0.013 delta(Tsk - Ta)UpperArm - 0.036 delta(Tsk - Ta)Chest - 0.223 delta(Tsk - Ta)Thigh-0.083 delta(Tsk - Ta)LowerLeg; R*2 = 0.752, respectively.

  1. Emergence of epidemics in rapidly varying networks

    International Nuclear Information System (INIS)

    Kohar, Vivek; Sinha, Sudeshna

    2013-01-01

    We describe a simple model mimicking disease spreading on a network with dynamically varying connections, and investigate the dynamical consequences of switching links in the network. Our central observation is that the disease cycles get more synchronized, indicating the onset of epidemics, as the underlying network changes more rapidly. This behavior is found for periodically switched links, as well as links that switch randomly in time. We find that the influence of changing links is more pronounced in networks where the nodes have lower degree, and the disease cycle has a longer infective stage. Further, when the switching of links is periodic we observe finer dynamical features, such as beating patterns in the emergent oscillations and resonant enhancement of synchronization, arising from the interplay between the time-scales of the connectivity changes and that of the epidemic outbreaks

  2. Belowground Plant–Herbivore Interactions Vary among Climate-Driven Range-Expanding Plant Species with Different Degrees of Novel Chemistry

    Directory of Open Access Journals (Sweden)

    Rutger A. Wilschut

    2017-10-01

    Full Text Available An increasing number of studies report plant range expansions to higher latitudes and altitudes in response to global warming. However, consequences for interactions with other species in the novel ranges are poorly understood. Here, we examine how range-expanding plant species interact with root-feeding nematodes from the new range. Root-feeding nematodes are ubiquitous belowground herbivores that may impact the structure and composition of natural vegetation. Because of their ecological novelty, we hypothesized that range-expanding plant species will be less suitable hosts for root-feeding nematodes than native congeneric plant species. In greenhouse and lab trials we compared nematode preference and performance of two root-feeding nematode species between range-expanding plant species and their congeneric natives. In order to understand differences in nematode preferences, we compared root volatile profiles of all range-expanders and congeneric natives. Nematode preferences and performances differed substantially among the pairs of range-expanders and natives. The range-expander that had the most unique volatile profile compared to its related native was unattractive and a poor host for nematodes. Other range-expanding plant species that differed less in root chemistry from native congeners, also differed less in nematode attraction and performance. We conclude that the three climate-driven range-expanding plant species studied varied considerably in their chemical novelty compared to their congeneric natives, and therefore affected native root-feeding nematodes in species-specific ways. Our data suggest that through variation in chemical novelty, range-expanding plant species may vary in their impacts on belowground herbivores in the new range.

  3. The master degree: A critical transition in STEM doctoral education

    Science.gov (United States)

    Lange, Sheila Edwards

    The need to broaden participation in the nation's science, technology, engineering, and mathematics (STEM) undergraduate and graduate programs is currently a matter of national urgency. The small number of women and underrepresented minorities (URM) earning doctoral degrees in STEM is particularly troubling given significant increases in the number of students earning master's degrees since 1990. In the decade between 1990 and 2000, the total number of master's recipients increased by 42%. During this same time period, the number of women earning master's degrees increased by 56%, African Americans increased by 132%, American Indians by 101%, Hispanics by 146%, and Asian Americans by 117% (Syverson, 2003). Growth in underrepresented group education at the master's level raises questions about the relationship between master's and doctoral education. Secondary data analysis of the Survey of Earned Doctorates (SED) was used to examine institutional pathways to the doctorate in STEM disciplines and transitions from master's to doctoral programs by race and gender. While the study revealed no significant gender differences in pathways, compared to White and Asian American students, URM students take significantly different pathways to the doctorate. URM students are significantly more likely to earn the bachelor's, master's, and doctoral degrees at three different institutions. Their path is significantly more likely to include earning a master's degree en route to the doctorate. Further, URM students are more likely to experience transition between the master's and doctoral degrees, and the transitions are not limited to those who earn master's degrees at master's-only institutions. These findings suggest that earning a master's degree is more often a stepping stone to the doctorate for URM students. Master's degree programs, therefore, have the potential to be a valuable resource for policymakers and graduate programs seeking to increase the diversity of URM students

  4. Childhood (Mis)Fortune, Educational Attainment, and Adult Health: Contingent Benefits of a College Degree?

    Science.gov (United States)

    Schafer, Markus H.; Wilkinson, Lindsay R.; Ferraro, Kenneth F.

    2013-01-01

    College-educated adults are healthier than other people in the United States, but selection bias complicates our understanding of how education influences health. This article focuses on the possibility that the health benefits of college may vary according to childhood (mis)fortune and people's propensity to attain a college degree in the first…

  5. An estimation of U.S. gasoline demand. A smooth time-varying cointegration approach

    International Nuclear Information System (INIS)

    Park, Sung Y.; Zhao, Guochang

    2010-01-01

    In this paper the U.S. gasoline demand from 1976 to 2008 is estimated using a time-varying cointegrating regression. We find that price elasticity increased rapidly during the late 1970s and then decreased until 1987. After a relatively small-scaled 'increase-decrease' cycle from 1987 to 2000, the price elasticity rose again after 2000. The time-varying change of the elasticities may be explained by the proportion of gasoline consumption to income and fluctuation of the degree of necessity. The result of the error correction model shows that a deviation from a long-run equilibrium is corrected quickly, and the welfare analysis illustrates there may be a gain by shifting the tax scheme from income tax to gasoline tax. (author)

  6. An estimation of U.S. gasoline demand. A smooth time-varying cointegration approach

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sung Y. [Department of Economics, University of Illinois, Urbana, IL 61801 (United States); The Wang Yanan Institute for Studies in Economics, Xiamen University, Xiamen, Fujian 361005 (China); Zhao, Guochang [Research School of Economics, College of Business and Economics, The Australian National University, Canberra, ACT 2601 (Australia)

    2010-01-15

    In this paper the U.S. gasoline demand from 1976 to 2008 is estimated using a time-varying cointegrating regression. We find that price elasticity increased rapidly during the late 1970s and then decreased until 1987. After a relatively small-scaled 'increase-decrease' cycle from 1987 to 2000, the price elasticity rose again after 2000. The time-varying change of the elasticities may be explained by the proportion of gasoline consumption to income and fluctuation of the degree of necessity. The result of the error correction model shows that a deviation from a long-run equilibrium is corrected quickly, and the welfare analysis illustrates there may be a gain by shifting the tax scheme from income tax to gasoline tax. (author)

  7. Decision Making on Allocating Urban Green Spaces Based upon Spatially-Varying Relationships between Urban Green Spaces and Urban Compaction Degree

    Directory of Open Access Journals (Sweden)

    Hsueh-Sheng Chang

    2015-09-01

    Full Text Available The compact city is becoming a prevailing paradigm in the world to control urban sprawl and achieve a pattern of sustainable urban development. However, discussions of the area's overcrowded neighborhoods, its health problems, and the destruction of its green areas have inspired self-examination with respect to the compact city paradigm. High population density attracts even more residents and frequently renders the existing urban green space (UGS insufficient for use as part of a living environment. Due to the unique benefits that these qualities confer, UGS allocation is now considered a significant contributing factor to urban livability. In addition, the UGS allocation may be different due to the presence of many spatial non-stationarity processes. Therefore, this study employs geographically-weighted regression (GWR to explore the unique and spatially-explicit relationships between the degree of urban compaction and UGS within the Taipei metropolitan area. Maps summarizing the GWR results demonstrate that there is significantly insufficient UGS allocation in the central area, which consists mainly of Taipei City. Townships with higher parameters contain UGS levels that better meet the needs of their residents. Overall, the exploration of conceptualizing spatial heterogeneity of relationships between the degree of urban compaction and UGS can provide insightful analyses for decision-making on allocating UGS.

  8. k-Degree Anonymity Model for Social Network Data Publishing

    Directory of Open Access Journals (Sweden)

    MACWAN, K. R.

    2017-11-01

    Full Text Available Publicly accessible platform for social networking has gained special attraction because of its easy data sharing. Data generated on such social network is analyzed for various activities like marketing, social psychology, etc. This requires preservation of sensitive attributes before it becomes easily accessible. Simply removing the personal identities of the users before publishing data is not enough to maintain the privacy of the individuals. The structure of the social network data itself reveals much information regarding its users and their connections. To resolve this problem, k-degree anonymous method is adopted. It emphasizes on the modification of the graph to provide at least k number of nodes that contain the same degree. However, this approach is not efficient on a huge amount of social data and the modification of the original data fails to maintain data usefulness. In addition to this, the current anonymization approaches focus on a degree sequence-based graph model which leads to major modification of the graph topological properties. In this paper, we have proposed an improved k-degree anonymity model that retain the social network structural properties and also to provide privacy to the individuals. Utility measurement approach for community based graph model is used to verify the performance of the proposed technique.

  9. Emotions in freely varying and mono-pitched vowels, acoustic and EGG analyses.

    Science.gov (United States)

    Waaramaa, Teija; Palo, Pertti; Kankare, Elina

    2015-12-01

    Vocal emotions are expressed either by speech or singing. The difference is that in singing the pitch is predetermined while in speech it may vary freely. It was of interest to study whether there were voice quality differences between freely varying and mono-pitched vowels expressed by professional actors. Given their profession, actors have to be able to express emotions both by speech and singing. Electroglottogram and acoustic analyses of emotional utterances embedded in expressions of freely varying vowels [a:], [i:], [u:] (96 samples) and mono-pitched protracted vowels (96 samples) were studied. Contact quotient (CQEGG) was calculated using 35%, 55%, and 80% threshold levels. Three different threshold levels were used in order to evaluate their effects on emotions. Genders were studied separately. The results suggested significant gender differences for CQEGG 80% threshold level. SPL, CQEGG, and F4 were used to convey emotions, but to a lesser degree, when F0 was predetermined. Moreover, females showed fewer significant variations than males. Both genders used more hypofunctional phonation type in mono-pitched utterances than in the expressions with freely varying pitch. The present material warrants further study of the interplay between CQEGG threshold levels and formant frequencies, and listening tests to investigate the perceptual value of the mono-pitched vowels in the communication of emotions.

  10. Influence of varying diets on radiosensitivity of quinea pigs

    International Nuclear Information System (INIS)

    Darenskaya, N.G.; Kuznetsova, S.S.; Lebengarts, Ya.Z.

    1975-01-01

    Seven groups of 25-day-old Guinea pig males given different diets during the entire observation period. Six groups received full-ration granulated mixed food varying in the contents of protein and cellulose, while the seventh group ate natural food. Experiments with irradiation failed to reveal any essential differences in radiosensitivity of animals grown on natural and mixed food, which enabled us to propose full-ration granulated mixed food for feeding laboratory guinea pigs

  11. Influence of varying diets on radiosensitivity of quinea pigs

    Energy Technology Data Exchange (ETDEWEB)

    Darenskaya, N G; Kuznetsova, S S; Lebengarts, Ya Z

    1975-07-01

    Seven groups of 25-day-old Guinea pig males given different diets during the entire observation period. Six groups received full-ration granulated mixed food varying in the contents of protein and cellulose, while the seventh group ate natural food. Experiments with irradiation failed to reveal any essential differences in radiosensitivity of animals grown on natural and mixed food, which enabled us to propose full-ration granulated mixed food for feeding laboratory guinea pigs.

  12. Chemometric, physicomechanical and rheological analysis of the sol-gel dynamics and degree of crosslinking of glycosidic polymers

    International Nuclear Information System (INIS)

    Choonara, Y E; Pillay, V; Singh, N; Ndesendo, V M K; Khan, R A

    2008-01-01

    The influence of calcium (Ca 2+ ), zinc (Zn 2+ ) and barium (Ba 2+ ) ions on the sol-gel interconversion dynamics, degree of crosslinking and the matrix resilience of crosslinked alginate gelispheres was determined. The dependent compositional and operational variables of crosslinking make it a challenging task to optimize the degree of crosslinking and the physicomechanical properties of alginate gelispheres. The combinatory approach of textural profiling, assessing pertinent rheological descriptors and chemometric model analysis of the sol-gel interconversion mechanisms and energy paradigms involved during crosslinking, hydration and erosion of gelispheres was explored. Molecular structural modelling of the gelispheres provided a mechanistic understanding of the sol-gel interconversion phenomena and their influence on the degree of crosslinking, the hydrational dynamics and gelisphere formation. Rheological analysis revealed offset yield point values of 6.1 mg ml -1 and 8.0 mg ml -1 were computed from fitted regression curves for determining the crosslinker concentration required for combinatory crosslinkers such as Ca/Zn/Ba ions and Ba/Zn, respectively. The influence of hydration on the erosion was a direct function of the gelispheres physicomechanical strength. Textural profiling characterized the gelisphere matrices for their resilience. The various crosslinkers interacted with monomeric units at varying intensities. Ba-crosslinked gelispheres were brittle with dense polymeric networks. Zn-crosslinked gelispheres produced permeable resilient matrices when hydrated and Ca-crosslinked gelispheres demonstrated intermediate resilience with greater G/M ratio alginate grades. Chemometrical analysis explicated a potential link between several phenomena such as the type of crosslinkers employed, the static shear-rate viscosity attained, the matrix resilience and the associated sol-gel mechanisms and energy paradigms of crosslinked gelispheres

  13. Asymmetric vibrations of shells of revolution having meridionally varying curvature and thickness

    International Nuclear Information System (INIS)

    Suzuki, Katsuyoshi; Kosawada, Tadashi; Miura, Kazuyuki.

    1988-01-01

    An exact method using power series expansions is presented for solving asymmetric free vibration problems for shells of revolution having meridionally varying curvature and thickness. The gaverning equations of motion and the boundary conditions are derived from the stationary conditions of the Lagrangian of the shells of revolution. The method is demonstrated for shells of revolution having elliptical, cycloidal, parabolical, catenary and hyperbolical meridional curvature. The natural frequencies are numerically calculated for these shells having second degree thickness variation. (author)

  14. Pharmacokinetics and Safety of Bortezomib in Patients with Advanced Malignancies and Varying Degrees of Liver Dysfunction: Phase 1 NCI Organ Dysfunction Working Group Study NCI-6432

    Science.gov (United States)

    LoRusso, Patricia M; Venkatakrishnan, Karthik; Ramanathan, Ramesh K; Sarantopoulos, John; Mulkerin, Daniel; Shibata, Stephen I; Hamilton, Anne; Dowlati, Afshin; Mani, Sridhar; Rudek, Michelle A; Takimoto, Chris H; Neuwirth, Rachel; Esseltine, Dixie-Lee; Ivy, Percy

    2013-01-01

    Purpose The proteasome inhibitor bortezomib undergoes oxidative hepatic metabolism. This study (NCI-6432; NCT00091117) was conducted to evaluate bortezomib pharmacokinetics and safety in patients with varying degrees of hepatic impairment, to inform dosing recommendations in these special populations. Methods Patients received bortezomib on days 1, 4, 8, and 11 of 21-day cycles. Patients were assigned to four hepatic function groups based on the National Cancer Institute Organ Dysfunction Working Group classification. Those with normal function received bortezomib at the 1.3 mg/m2 standard dose. Patients with severe, moderate, and mild impairment received escalating doses from 0.5, 0.7, and 1.0 mg/m2, respectively, up to a 1.3 mg/m2 maximum. Serial blood samples were collected for 24 hours post-dose on days 1 and 8, cycle 1, for bortezomib plasma concentration measurements. Results Sixty-one patients were treated, including 14 with normal hepatic function and 17, 12, and 18 with mild, moderate, and severe impairment, respectively. Mild hepatic impairment did not alter dose-normalized bortezomib exposure (AUC0-tlast) or Cmax compared with patients with normal function. Mean dose-normalized AUC0-tlast was increased by approximately 60% on day 8 in patients with moderate or severe impairment. Conclusions Patients with mild hepatic impairment do not require a starting dose adjustment of bortezomib. Patients with moderate or severe hepatic impairment should be started at a reduced dose of 0.7 mg/m2. PMID:22394984

  15. Degree distribution in discrete case

    International Nuclear Information System (INIS)

    Wang, Li-Na; Chen, Bin; Yan, Zai-Zai

    2011-01-01

    Vertex degree of many network models and real-life networks is limited to non-negative integer. By means of measure and integral, the relation of the degree distribution and the cumulative degree distribution in discrete case is analyzed. The degree distribution, obtained by the differential of its cumulative, is only suitable for continuous case or discrete case with constant degree change. When degree change is not a constant but proportional to degree itself, power-law degree distribution and its cumulative have the same exponent and the mean value is finite for power-law exponent greater than 1. -- Highlights: → Degree change is the crux for using the cumulative degree distribution method. → It suits for discrete case with constant degree change. → If degree change is proportional to degree, power-law degree distribution and its cumulative have the same exponent. → In addition, the mean value is finite for power-law exponent greater than 1.

  16. Genome-wide analysis in Brazilian Xavante Indians reveals low degree of admixture.

    Science.gov (United States)

    Kuhn, Patricia C; Horimoto, Andréa R V Russo; Sanches, José Maurício; Vieira Filho, João Paulo B; Franco, Luciana; Fabbro, Amaury Dal; Franco, Laercio Joel; Pereira, Alexandre C; Moises, Regina S

    2012-01-01

    Characterization of population genetic variation and structure can be used as tools for research in human genetics and population isolates are of great interest. The aim of the present study was to characterize the genetic structure of Xavante Indians and compare it with other populations. The Xavante, an indigenous population living in Brazilian Central Plateau, is one of the largest native groups in Brazil. A subset of 53 unrelated subjects was selected from the initial sample of 300 Xavante Indians. Using 86,197 markers, Xavante were compared with all populations of HapMap Phase III and HGDP-CEPH projects and with a Southeast Brazilian population sample to establish its population structure. Principal Components Analysis showed that the Xavante Indians are concentrated in the Amerindian axis near other populations of known Amerindian ancestry such as Karitiana, Pima, Surui and Maya and a low degree of genetic admixture was observed. This is consistent with the historical records of bottlenecks experience and cultural isolation. By calculating pair-wise F(st) statistics we characterized the genetic differentiation between Xavante Indians and representative populations of the HapMap and from HGDP-CEPH project. We found that the genetic differentiation between Xavante Indians and populations of Ameridian, Asian, European, and African ancestry increased progressively. Our results indicate that the Xavante is a population that remained genetically isolated over the past decades and can offer advantages for genome-wide mapping studies of inherited disorders.

  17. Phase transition of the susceptible-infected-susceptible dynamics on time-varying configuration model networks

    Science.gov (United States)

    St-Onge, Guillaume; Young, Jean-Gabriel; Laurence, Edward; Murphy, Charles; Dubé, Louis J.

    2018-02-01

    We present a degree-based theoretical framework to study the susceptible-infected-susceptible (SIS) dynamics on time-varying (rewired) configuration model networks. Using this framework on a given degree distribution, we provide a detailed analysis of the stationary state using the rewiring rate to explore the whole range of the time variation of the structure relative to that of the SIS process. This analysis is suitable for the characterization of the phase transition and leads to three main contributions: (1) We obtain a self-consistent expression for the absorbing-state threshold, able to capture both collective and hub activation. (2) We recover the predictions of a number of existing approaches as limiting cases of our analysis, providing thereby a unifying point of view for the SIS dynamics on random networks. (3) We obtain bounds for the critical exponents of a number of quantities in the stationary state. This allows us to reinterpret the concept of hub-dominated phase transition. Within our framework, it appears as a heterogeneous critical phenomenon: observables for different degree classes have a different scaling with the infection rate. This phenomenon is followed by the successive activation of the degree classes beyond the epidemic threshold.

  18. Degree of multicollinearity and variables involved in linear dependence in additive-dominant models Grau de multicolinearidade e variáveis envolvidas na dependência linear em modelos aditivo-dominantes

    Directory of Open Access Journals (Sweden)

    Juliana Petrini

    2012-12-01

    Full Text Available The objective of this work was to assess the degree of multicollinearity and to identify the variables involved in linear dependence relations in additive-dominant models. Data of birth weight (n=141,567, yearling weight (n=58,124, and scrotal circumference (n=20,371 of Montana Tropical composite cattle were used. Diagnosis of multicollinearity was based on the variance inflation factor (VIF and on the evaluation of the condition indexes and eigenvalues from the correlation matrix among explanatory variables. The first model studied (RM included the fixed effect of dam age class at calving and the covariates associated to the direct and maternal additive and non-additive effects. The second model (R included all the effects of the RM model except the maternal additive effects. Multicollinearity was detected in both models for all traits considered, with VIF values of 1.03 - 70.20 for RM and 1.03 - 60.70 for R. Collinearity increased with the increase of variables in the model and the decrease in the number of observations, and it was classified as weak, with condition index values between 10.00 and 26.77. In general, the variables associated with additive and non-additive effects were involved in multicollinearity, partially due to the natural connection between these covariables as fractions of the biological types in breed composition.O objetivo deste trabalho foi avaliar o grau de multicolinearidade e identificar as variáveis envolvidas na dependência linear em modelos aditivo-dominantes. Foram utilizados dados de peso ao nascimento (n=141.567, peso ao ano (n=58.124 e perímetro escrotal (n=20.371 de bovinos de corte compostos Montana Tropical. O diagnóstico de multicolinearidade foi baseado no fator de inflação de variância (VIF e no exame dos índices de condição e dos autovalores da matriz de correlações entre as variáveis explanatórias. O primeiro modelo estudado (RM incluiu o efeito fixo de classe de idade da mãe ao parto e

  19. Impact of degree truncation on the spread of a contagious process on networks.

    Science.gov (United States)

    Harling, Guy; Onnela, Jukka-Pekka

    2018-03-01

    Understanding how person-to-person contagious processes spread through a population requires accurate information on connections between population members. However, such connectivity data, when collected via interview, is often incomplete due to partial recall, respondent fatigue or study design, e.g., fixed choice designs (FCD) truncate out-degree by limiting the number of contacts each respondent can report. Past research has shown how FCD truncation affects network properties, but its implications for predicted speed and size of spreading processes remain largely unexplored. To study the impact of degree truncation on predictions of spreading process outcomes, we generated collections of synthetic networks containing specific properties (degree distribution, degree-assortativity, clustering), and also used empirical social network data from 75 villages in Karnataka, India. We simulated FCD using various truncation thresholds and ran a susceptible-infectious-recovered (SIR) process on each network. We found that spreading processes propagated on truncated networks resulted in slower and smaller epidemics, with a sudden decrease in prediction accuracy at a level of truncation that varied by network type. Our results have implications beyond FCD to truncation due to any limited sampling from a larger network. We conclude that knowledge of network structure is important for understanding the accuracy of predictions of process spread on degree truncated networks.

  20. The Influence of Slowly Varying Mass on Severity of Dynamics Nonlinearity of Bearing-Rotor Systems with Pedestal Looseness

    Directory of Open Access Journals (Sweden)

    Mian Jiang

    2018-01-01

    Full Text Available Nonlinearity measure is proposed to investigate the influence of slowly varying mass on severity of dynamics nonlinearity of bearing-rotor systems with pedestal looseness. A nonlinear mathematical model including the effect of slowly varying disk mass is developed for a bearing-rotor system with pedestal looseness. The varying of equivalent disk mass is described by a cosine function, and the amplitude coefficient is used as a control parameter. Then, nonlinearity measure is employed to quantify the severity of dynamics nonlinearity of bearing-rotor systems. With the increasing of looseness clearances, the curves that denote the trend of nonlinearity degree are plotted for each amplitude coefficient of mass varying. It can be concluded that larger amplitude coefficients of the disk mass varying will have more influence on the severity of dynamics nonlinearity and generation of chaotic behaviors in rotor systems with pedestal looseness.

  1. Single cell cultures of Drosophila neuroectodermal and mesectodermal central nervous system progenitors reveal different degrees of developmental autonomy.

    Science.gov (United States)

    Lüer, Karin; Technau, Gerhard M

    2009-08-03

    The Drosophila embryonic central nervous system (CNS) develops from two sets of progenitor cells, neuroblasts and ventral midline progenitors, which behave differently in many respects. Neuroblasts derive from the neurogenic region of the ectoderm and form the lateral parts of the CNS. Ventral midline precursors are formed by two rows of mesectodermal cells and build the CNS midline. There is plenty of evidence that individual identities are conferred to precursor cells by positional information in the ectoderm. It is unclear, however, how far the precursors can maintain their identities and developmental properties in the absence of normal external signals. To separate the respective contributions of autonomous properties versus extrinsic signals during their further development, we isolated individual midline precursors and neuroectodermal precursors at the pre-mitotic gastrula stage, traced their development in vitro, and analyzed the characteristics of their lineages in comparison with those described for the embryo. Although individually cultured mesectodermal cells exhibit basic characteristics of CNS midline progenitors, the clones produced by these progenitors differ from their in situ counterparts with regard to cell numbers, expression of molecular markers, and the separation of neuronal and glial fate. In contrast, clones derived from individually cultured precursors taken from specific dorsoventral zones of the neuroectoderm develop striking similarities to the lineages of neuroblasts that normally delaminate from these zones and develop in situ. This in vitro analysis allows for the first time a comparison of the developmental capacities in situ and in vitro of individual neural precursors of defined spatial and temporal origin. The data reveal that cells isolated at the pre-mitotic and pre-delamination stage express characteristics of the progenitor type appropriate to their site of origin in the embryo. However, presumptive neuroblasts, once

  2. Wave scattering by an axisymmetric ice floe of varying thickness

    Science.gov (United States)

    Bennetts, Luke G.; Biggs, Nicholas R. T.; Porter, David

    2009-04-01

    The problem of water wave scattering by a circular ice floe, floating in fluid of finite depth, is formulated and solved numerically. Unlike previous investigations of such situations, here we allow the thickness of the floe (and the fluid depth) to vary axisymmetrically and also incorporate a realistic non-zero draught. A numerical approximation to the solution of this problem is obtained to an arbitrary degree of accuracy by combining a Rayleigh-Ritz approximation of the vertical motion with an appropriate variational principle. This numerical solution procedure builds upon the work of Bennets et al. (2007, J. Fluid Mech., 579, 413-443). As part of the numerical formulation, we utilize a Fourier cosine expansion of the azimuthal motion, resulting in a system of ordinary differential equations to solve in the radial coordinate for each azimuthal mode. The displayed results concentrate on the response of the floe rather than the scattered wave field and show that the effects of introducing the new features of varying floe thickness and a realistic draught are significant.

  3. Diffractometric method for determining the degree of crystallinity of materials

    Energy Technology Data Exchange (ETDEWEB)

    Chukhchin, D. G., E-mail: dimatsch@mail.ru; Malkov, A. V.; Tyshkunova, I. V.; Mayer, L. V.; Novozhilov, E. V. [Lomonosov Northen (Arctic) Federal University (Russian Federation)

    2016-05-15

    A new method for determining the degree of crystallinity of a material from X-ray diffraction data has been developed. The method is based on estimating the rate of change in function I = f(2θ) in the entire range of scattering angles. A calculation is performed using the ratio of the integral modulus of the first derivative of intensity with respect to angle 2θ to the integral area under the diffraction pattern curve. The method was tested on two substances with known amorphous and crystalline components. A linear relationship is revealed between the specified ratio of crystalline and amorphous parts and the calculated crystallinity index. The proposed method allows one to estimate impartially and compare the degree of crystallinity for samples of different nature.

  4. LMI-based gain scheduled controller synthesis for a class of linear parameter varying systems

    DEFF Research Database (Denmark)

    Bendtsen, Jan Dimon; Anderson, Brian; Lanzon, Alexander

    2006-01-01

    This paper presents a novel method for constructing controllers for a class of single-input multiple-output (SIMO) linear parameter varying (LPV) systems. This class of systems encompasses many physical systems, in particular systems where individual components vary with time, and is therefore...... of significant practical relevance to control designers. The control design presented in this paper has the properties that the system matrix of the closed loop is multi-affine in the various scalar parameters, and that the resulting controller ensures a certain degree of stability for the closed loop even when...... as a standard linear time-invariant (LTI) design combined with a set of linear matrix inequalities, which can be solved efficiently with software tools. The design procedure is illustrated by a numerical example....

  5. Psychometric Functioning of the MMPI-2-RF VRIN-r and TRIN-r Scales with Varying Degrees of Randomness, Acquiescence, and Counter-Acquiescence

    Science.gov (United States)

    Handel, Richard W.; Ben-Porath, Yossef S.; Tellegen, Auke; Archer, Robert P.

    2010-01-01

    In the present study, the authors evaluated the effects of increasing degrees of simulated non-content-based (random or fixed) responding on scores on the newly developed Variable Response Inconsistency-Revised (VRIN-r) and True Response Inconsistency-Revised (TRIN-r) scales of the Minnesota Multiphasic Personality Inventory-2 Restructured Form…

  6. Pursuit of STEM: Factors shaping degree completion for African American females in STEM

    Science.gov (United States)

    Wilkins, Ashlee N.

    The primary purpose of the study was to examine secondary data from the Cooperative Institutional Research Program (CIRP) Freshman and College Senior Surveys to investigate factors shaping degree aspirations for African American female undergraduates partaking in science, technology, engineering, and mathematics (STEM) majors. Hierarchical multiple regression was used to analyze the data and identify relationships between independent variables in relation to the dependent variable. The findings of the study reveal four key variables that were predictive of degree completion for African American females in STEM. Father's education, SAT composite, highest degree planned, and self-perception were positive predictors for females; while independent variable overall sense of community among students remained a negative predictor. Lastly implications for education and recommendations for future research were discussed.

  7. GRGM900C: A Degree 900 Lunar Gravity Model from GRAIL Primary and Extended Mission Data

    Science.gov (United States)

    Lemoine, Frank G.; Goossens, Sander; Sabaka, Terence J.; Nicholas, Joseph B.; Mazarico, Erwan; Rowlands, David D.; Bryant, D. Loomis; Chinn, Douglas S.; Neumann, Gregory A.; Smith, David E.; hide

    2014-01-01

    We have derived a gravity field solution in spherical harmonics to degree and order 900, GRGM900C, from the tracking data of the Gravity Recovery and Interior Laboratory (GRAIL) Primary (1 March to 29 May 2012) and Extended Missions (30 August to 14 December 2012). A power law constraint of 3.6 × 10(exp -4)/l(exp 2) was applied only for degree l greater than 600. The model produces global correlations of gravity, and gravity predicted from lunar topography of greater than or equal to 0.98 through degree 638. The model's degree strength varies from a minimum of 575-675 over the central nearside and farside to 900 over the polar regions. The model fits the Extended Mission Ka-Band Range Rate data through 17 November 2012 at 0.13 micrometers/s RMS, whereas the last month of Ka-Band Range-Rate data obtained from altitudes of 2-10 km fit at 0.98 micrometers/s RMS, indicating that there is still signal inherent in the tracking data beyond degree 900.

  8. Degree of adaptive response in urban tolerant birds shows influence of habitat-of-origin

    Directory of Open Access Journals (Sweden)

    Lawrence E. Conole

    2014-03-01

    Full Text Available Urban exploiters and adapters are often coalesced under a term of convenience as ‘urban tolerant’. This useful but simplistic characterisation masks a more nuanced interplay between and within assemblages of birds that are more or less well adapted to a range of urban habitats. I test the hypotheses that objectively-defined urban exploiter and suburban adapter assemblages within the broad urban tolerant grouping in Melbourne vary in their responses within the larger group to predictor variables, and that the most explanatory predictor variables vary between the two assemblages. A paired, partitioned analysis of exploiter and adapter preferences for points along the urban–rural gradient was undertaken to decompose the overall trend into diagnosable parts for each assemblage. In a similar way to that in which time since establishment has been found to be related to high urban densities of some bird species and biogeographic origin predictive of urban adaptation extent, habitat origins of members of bird assemblages influence the degree to which they become urban tolerant. Bird species that objectively classify as urban tolerant will further classify as either exploiters or adapters according to the degree of openness of their habitats-of-origin.

  9. Coherence degree of the fundamental Bessel-Gaussian beam in turbulent atmosphere

    Science.gov (United States)

    Lukin, Igor P.

    2017-11-01

    In this article the coherence of a fundamental Bessel-Gaussian optical beam in turbulent atmosphere is analyzed. The problem analysis is based on the solution of the equation for the transverse second-order mutual coherence function of a fundamental Bessel-Gaussian optical beam of optical radiation. The behavior of a coherence degree of a fundamental Bessel-Gaussian optical beam depending on parameters of an optical beam and characteristics of turbulent atmosphere is examined. It was revealed that at low levels of fluctuations in turbulent atmosphere the coherence degree of a fundamental Bessel-Gaussian optical beam has the characteristic oscillating appearance. At high levels of fluctuations in turbulent atmosphere the coherence degree of a fundamental Bessel-Gaussian optical beam is described by an one-scale decreasing curve which in process of increase of level of fluctuations on a line of formation of a laser beam becomes closer to the same characteristic of a spherical optical wave.

  10. [Dynamics of change of ureaplasma laboratory strain titers and quantity of their DNA in transport medium at varying temperature].

    Science.gov (United States)

    Gamova, N A; Ivanova, T A

    2013-01-01

    Study of preservation dynamics of ureaplasma laboratory strain live cultures and their DNA in transport medium at varying temperature. The study was carried out in laboratory strains Ureaplasma urealyticum serotype 8 and Ureaplasma parvum serotype 1. The quantity of live ureaplasmas was determined by method of tenfold dilutions in liquid medium. The growth of ureaplasmas was registered by changes in the color of the cultivation medium due to its alkalization by metabolism products and expressed in CCU/ml. DNA quantity in samples was determined by real time PCR performed by using Florocenosis-micoplasmas-FL test system produced by ILS. Live ureaplasmas wer shown to be preserved in transport medium at 4 degrees C for 12 - 29 days, at 18 - 22 degrees C--for 9 - 20 days and at 37 degrees C--for only 2 days. In samples incubated at 37 degrees C the quantity of live ureaplasmas increased and then sharply decreased to 0, at lower temperature titers of the cells decreased smoothly. The quantity of ureaplasma DNA in the process of their incubation did not change significantly. Fundamental differences in the duration of survival of U. urealyticum strain and U. parvum strain in transport medium at varying temperature were not detected. Based on the studies performed a practical conclusion can be drawn that in cases of emergency when clinical material transportation is necessary its storage in transport medium for several days is acceptable.

  11. Phase behaviour of oat β-glucan/sodium caseinate mixtures varying in molecular weight.

    Science.gov (United States)

    Agbenorhevi, Jacob K; Kontogiorgos, Vassilis; Kasapis, Stefan

    2013-05-01

    The isothermal phase behaviour at 5 °C of mixtures of sodium caseinate and oat β-glucan isolates varying in molecular weight (MW) was investigated by means of phase diagram construction, rheometry, fluorescence microscopy and electrophoresis. Phase diagrams indicated that the compatibility of the β-glucan/sodium caseinate system increases as β-glucan MW decreases. Images of mixtures taken at various biopolymer concentrations revealed phase separated domains. Results also revealed that at the state of thermodynamic equilibrium, lower MW samples yielded considerable viscosity in the mixture. At equivalent hydrodynamic volume of β-glucan in the mixtures, samples varying in molecular weight exhibited similar flow behaviour. A deviation dependent on the protein concentration was observed for the high MW sample in the concentrated regime due to the size of β-glucan aggregates formed. Results demonstrate that by controlling the structural features of β-glucan in mixtures with sodium caseinate, informed manipulation of rheological properties in these systems can be achieved. Copyright © 2012 Elsevier Ltd. All rights reserved.

  12. Students' Views on Thesis Supervision in International Master's Degree Programmes in Finnish Universities

    Science.gov (United States)

    Filippou, Kalypso; Kallo, Johanna; Mikkilä-Erdmann, Mirjamaija

    2017-01-01

    This paper employs an intercultural perspective to examine students' views on master's thesis supervision and the roles and responsibilities of supervisors and students. The 302 respondents who answered the online questionnaire were enrolled in international master's degree programmes in four Finnish universities. The study revealed asymmetric…

  13. Outcomes of dental hygiene baccalaureate degree education in Canada.

    Science.gov (United States)

    Kanji, Zul; Sunell, Susanne; Boschma, Geertje; Imai, Pauline; Craig, Bonnie J

    2011-03-01

    There is little published literature about the outcomes of dental hygiene baccalaureate degree education, particularly in Canada. Since there are various dental hygiene entry-to-practice educational models in Canada, exploring baccalaureate dental hygiene education is becoming an increasingly important subject. The purpose of this study was to explore the personal outcomes and dental hygiene practice outcomes of dental hygiene degree-completion education in Canada from the perspectives of diploma dental hygienists who have continued their education to the bachelor's degree level. This study employed a qualitative phenomenological design, using a maximum variation purposeful sampling strategy. Data generation occurred with sixteen dental hygienists across Canada through individual semistructured interviews. Interviews were audiorecorded, transcribed verbatim, and coded for data analysis, involving pattern recognition and thematic development. Themes that emerged included changes in self-perception, values, and knowledge base. Changes in self-perception were reflected in a reported increase in self-confidence and perceived credibility. Changes in values included a greater appreciation for lifelong learning. Advancements in knowledge strengthened the development of specific abilities that ultimately influenced participants' dental hygiene practice. These abilities included an increased ability to think critically, to make evidence-based decisions, and to provide more comprehensive care. Participants also commented on having more career opportunities available to them outside of the private clinical practice setting. These results reveal important insights into the impact of earning a dental hygiene baccalaureate degree on oneself and one's dental hygiene practice.

  14. Tensions related to implementation of postgraduate degree projects in specialist nursing education.

    Science.gov (United States)

    German Millberg, Lena; Berg, Linda; Lindström, Irma; Petzäll, Kerstin; Öhlén, Joakim

    2011-04-01

    In conjunction with the introduction of the Bologna process in Sweden, specialist nursing education programmes were moved up to the second cycle of higher education with the opportunity to take a one-year master's degree, which also meant that students would undertake a degree project carrying 15 ECTS. The purpose of this study was to examine the introduction of postgraduate degree projects on the second-cycle level into Swedish specialist nursing programmes in accordance with the Bologna process. Five universities were involved and the study design took the form of action research. Problem formulation, planning, evaluation and follow-up with reflection led to new actions over a period of 2 1/2 years. Through a review of local curriculum documents, the implementation of a postgraduate degree project was monitored and these reviews, together with field notes, were analysed by means of constant comparative analysis. The results revealed a variety of tensions that arose when postgraduate degree projects were introduced, taking the form of differing views on the relationship between research, clinical development, specific professional objectives and academic objectives. These tensions were reflected in six areas of change. In summary, it can be noted that implementation of the postgraduate degree projects highlighted tensions related to basic views of learning. Copyright © 2010 Elsevier Ltd. All rights reserved.

  15. Whole-genome sequencing of Campylobacter jejuni isolated from Danish routine human stool samples reveals surprising degree of clustering

    DEFF Research Database (Denmark)

    Joensen, K G; Kuhn, K G; Müller, L

    2018-01-01

    OBJECTIVES: Outbreaks of Campylobacter are traditionally considered to be rare, however rather than being the true nature of the disease, this may reflect our present inability to detect them. The aim of this study was to determine the genetic and epidemiological degree of clustering among Campyl...... of the most important cause of bacterial gastroenteritis in the industrialized world....

  16. Output-Only Modal Parameter Recursive Estimation of Time-Varying Structures via a Kernel Ridge Regression FS-TARMA Approach

    Directory of Open Access Journals (Sweden)

    Zhi-Sai Ma

    2017-01-01

    Full Text Available Modal parameter estimation plays an important role in vibration-based damage detection and is worth more attention and investigation, as changes in modal parameters are usually being used as damage indicators. This paper focuses on the problem of output-only modal parameter recursive estimation of time-varying structures based upon parameterized representations of the time-dependent autoregressive moving average (TARMA. A kernel ridge regression functional series TARMA (FS-TARMA recursive identification scheme is proposed and subsequently employed for the modal parameter estimation of a numerical three-degree-of-freedom time-varying structural system and a laboratory time-varying structure consisting of a simply supported beam and a moving mass sliding on it. The proposed method is comparatively assessed against an existing recursive pseudolinear regression FS-TARMA approach via Monte Carlo experiments and shown to be capable of accurately tracking the time-varying dynamics in a recursive manner.

  17. Comparison of two-stage thermophilic (68 degrees C/55 degrees C) anaerobic digestion with one-stage thermophilic (55 degrees C) digestion of cattle manure.

    Science.gov (United States)

    Nielsen, H B; Mladenovska, Z; Westermann, P; Ahring, B K

    2004-05-05

    A two-stage 68 degrees C/55 degrees C anaerobic degradation process for treatment of cattle manure was studied. In batch experiments, an increase of the specific methane yield, ranging from 24% to 56%, was obtained when cattle manure and its fractions (fibers and liquid) were pretreated at 68 degrees C for periods of 36, 108, and 168 h, and subsequently digested at 55 degrees C. In a lab-scale experiment, the performance of a two-stage reactor system, consisting of a digester operating at 68 degrees C with a hydraulic retention time (HRT) of 3 days, connected to a 55 degrees C reactor with 12-day HRT, was compared with a conventional single-stage reactor running at 55 degrees C with 15-days HRT. When an organic loading of 3 g volatile solids (VS) per liter per day was applied, the two-stage setup had a 6% to 8% higher specific methane yield and a 9% more effective VS-removal than the conventional single-stage reactor. The 68 degrees C reactor generated 7% to 9% of the total amount of methane of the two-stage system and maintained a volatile fatty acids (VFA) concentration of 4.0 to 4.4 g acetate per liter. Population size and activity of aceticlastic methanogens, syntrophic bacteria, and hydrolytic/fermentative bacteria were significantly lower in the 68 degrees C reactor than in the 55 degrees C reactors. The density levels of methanogens utilizing H2/CO2 or formate were, however, in the same range for all reactors, although the degradation of these substrates was significantly lower in the 68 degrees C reactor than in the 55 degrees C reactors. Temporal temperature gradient electrophoresis profiles (TTGE) of the 68 degrees C reactor demonstrated a stable bacterial community along with a less divergent community of archaeal species. Copyright 2004 Wiley Periodicals, Inc.

  18. Cadmium-109 uptake by tumors derived from Balb C/3T3 cell lines with varying degrees of the transformed phenotype

    International Nuclear Information System (INIS)

    Morton, K.; Alazraki, N.; Winge, D.; Lynch, R.E.

    1986-01-01

    To determine if tumors are rich in metallothionein, the authors measured the vivo uptake of subcutaneously-injected carrier-free cadmium-109 in tumors and in normal tissues of Balb/C mice. The tumors were grown in the mice from cultured Balb/3T3 cells transformed by the Moloney murine sarcoma virus. Uptake of cadmium-109 per gram of tissue was greatest for liver, kidney, and spleen. However, tumor uptake of cadmium-109 was markedly greater than that in blood, skeletal muscle, bones, intestine or adipose tissue. B Sephadex G-75 chromatography, the radioactivity in tumor and in liver lysates eluted with cytochrome-C, a molecule similar in molecular weight to metal-lothionein. To determine if metallothionein levels are related to the degree of malignancy of tumors, cadmium-109 uptake in the tumors from the virally-transformed cells was compared to that in tumors from non-transformed Balb/3T3 cells and two derivative chemically transformed cell lines. There was strong correlation between the substrate-independent growth in soft agarose of the four cell lines, the rate of growth of the corresponding tumors, and the amount of cadmium-109 uptake in the tumors. The authors conclude that metallothionein levels may be elevated in tumors as a function of the degree of expression of the transformed phenotype

  19. Vector-field statistics for the analysis of time varying clinical gait data.

    Science.gov (United States)

    Donnelly, C J; Alexander, C; Pataky, T C; Stannage, K; Reid, S; Robinson, M A

    2017-01-01

    In clinical settings, the time varying analysis of gait data relies heavily on the experience of the individual(s) assessing these biological signals. Though three dimensional kinematics are recognised as time varying waveforms (1D), exploratory statistical analysis of these data are commonly carried out with multiple discrete or 0D dependent variables. In the absence of an a priori 0D hypothesis, clinicians are at risk of making type I and II errors in their analyis of time varying gait signatures in the event statistics are used in concert with prefered subjective clinical assesment methods. The aim of this communication was to determine if vector field waveform statistics were capable of providing quantitative corroboration to practically significant differences in time varying gait signatures as determined by two clinically trained gait experts. The case study was a left hemiplegic Cerebral Palsy (GMFCS I) gait patient following a botulinum toxin (BoNT-A) injection to their left gastrocnemius muscle. When comparing subjective clinical gait assessments between two testers, they were in agreement with each other for 61% of the joint degrees of freedom and phases of motion analysed. For tester 1 and tester 2, they were in agreement with the vector-field analysis for 78% and 53% of the kinematic variables analysed. When the subjective analyses of tester 1 and tester 2 were pooled together and then compared to the vector-field analysis, they were in agreement for 83% of the time varying kinematic variables analysed. These outcomes demonstrate that in principle, vector-field statistics corroborates with what a team of clinical gait experts would classify as practically meaningful pre- versus post time varying kinematic differences. The potential for vector-field statistics to be used as a useful clinical tool for the objective analysis of time varying clinical gait data is established. Future research is recommended to assess the usefulness of vector-field analyses

  20. Cognitive alexithymia is associated with the degree of risk for psychosis.

    Directory of Open Access Journals (Sweden)

    Jorien van der Velde

    Full Text Available Alexithymia is a personality construct denoting emotion processing problems. It has been suggested to encompass two dimensions: a cognitive and affective dimension. The cognitive dimension is characterized by difficulties in identifying, verbalizing and analyzing emotions, while the affective dimension reflects the level of emotional arousal and imagination. Alexithymia has been previously proposed as a risk factor for developing psychosis. More specifically, the two alexithymia dimensions might be differentially related to the vulnerability for psychosis. Therefore, we examined the two dimensions of alexithymia, measured with the BVAQ in 94 siblings of patients with schizophrenia, 52 subjects at ultra-high risk (UHR for developing psychosis, 38 patients with schizophrenia and 109 healthy controls. The results revealed that siblings and patients had higher levels of cognitive alexithymia compared to controls. In addition, subjects at UHR for psychosis had even higher levels of cognitive alexithymia compared to the siblings. The levels of affective alexithymia in siblings and patients were equal to controls. However, UHR individuals had significantly lower levels of affective alexithymia (i.e. higher levels of emotional arousal and fantasizing compared to controls. Alexithymia was further related to subclinical levels of negative and depressive symptoms. These findings indicate that alexithymia varies parametrically with the degree of risk for psychosis. More specifically, a type-II alexithymia pattern, with high levels of cognitive alexithymia and normal or low levels of affective alexithymia, might be a vulnerability factor for psychosis.

  1. Single cell cultures of Drosophila neuroectodermal and mesectodermal central nervous system progenitors reveal different degrees of developmental autonomy

    Directory of Open Access Journals (Sweden)

    Technau Gerhard M

    2009-08-01

    Full Text Available Abstract Background The Drosophila embryonic central nervous system (CNS develops from two sets of progenitor cells, neuroblasts and ventral midline progenitors, which behave differently in many respects. Neuroblasts derive from the neurogenic region of the ectoderm and form the lateral parts of the CNS. Ventral midline precursors are formed by two rows of mesectodermal cells and build the CNS midline. There is plenty of evidence that individual identities are conferred to precursor cells by positional information in the ectoderm. It is unclear, however, how far the precursors can maintain their identities and developmental properties in the absence of normal external signals. Results To separate the respective contributions of autonomous properties versus extrinsic signals during their further development, we isolated individual midline precursors and neuroectodermal precursors at the pre-mitotic gastrula stage, traced their development in vitro, and analyzed the characteristics of their lineages in comparison with those described for the embryo. Although individually cultured mesectodermal cells exhibit basic characteristics of CNS midline progenitors, the clones produced by these progenitors differ from their in situ counterparts with regard to cell numbers, expression of molecular markers, and the separation of neuronal and glial fate. In contrast, clones derived from individually cultured precursors taken from specific dorsoventral zones of the neuroectoderm develop striking similarities to the lineages of neuroblasts that normally delaminate from these zones and develop in situ. Conclusion This in vitro analysis allows for the first time a comparison of the developmental capacities in situ and in vitro of individual neural precursors of defined spatial and temporal origin. The data reveal that cells isolated at the pre-mitotic and pre-delamination stage express characteristics of the progenitor type appropriate to their site of origin in

  2. Brown Dwarf Variability: What's Varying and Why?

    Science.gov (United States)

    Marley, Mark Scott

    2014-01-01

    Surveys by ground based telescopes, HST, and Spitzer have revealed that brown dwarfs of most spectral classes exhibit variability. The spectral and temporal signatures of the variability are complex and apparently defy simplistic classification which complicates efforts to model the changes. Important questions include understanding if clearings are forming in an otherwise uniform cloud deck or if thermal perturbations, perhaps associated with breaking gravity waves, are responsible. If clouds are responsible how long does it take for the atmospheric thermal profile to relax from a hot cloudy to a cooler cloudless state? If thermal perturbations are responsible then what atmospheric layers are varying? How do the observed variability timescales compare to atmospheric radiative, chemical, and dynamical timescales? I will address such questions by presenting modeling results for time-varying partly cloudy atmospheres and explore the importance of various atmospheric processes over the relevant timescales for brown dwarfs of a range of effective temperatures. Regardless of the origin of the observed variability, the complexity seen in the atmospheres of the field dwarfs hints at the variability that we may encounter in the next few years in directly imaged young Jupiters. Thus understanding the nature of variability in the field dwarfs, including sensitivity to gravity and metallicity, is of particular importance for exoplanet characterization.

  3. Why do different people choose different university degrees? Motivation and the choice of degree

    Directory of Open Access Journals (Sweden)

    Anya eSkatova

    2014-11-01

    Full Text Available Different people choose which undergraduate degree to study at the university for different reasons. To date, there have been limited attempts to identify individual differences in motivation that drive the undergraduate degree choice. We identified that people choose university degrees for four reasons: career concerns (Career, intrinsic interest (Interest in the subject, an opportunity to help others (Helping and because they are looking for an easy option into higher education (Loafing. We investigated whether these motivation apply to the choice of undergraduate degree in two samples: (1 undergraduate (N = 989 and (2 prospective (N = 896 students. We developed the Motivations Influencing Course Choice (MICC questionnaire to measure these motivations. Scales of Helping, Career, Loafing and Interest showed good psychometric properties, showed validity with respect to general life goals and personality traits, and predicted actual and prospective degree choices. We demonstrated that medical degrees were chosen due to a mixture of Helping and Career, while engineering degrees were associated with Career and low interest in the degree. The choice of art and humanities degrees was driven by Interest and low concern about future career, accompanied with high Loafing. We also demonstrated gender differences: females were high in Helping (both samples and Interest (only in undergraduate sample motivation, while males scored higher in Career (only in undergraduate sample and Loafing (both samples. The findings can feed into both theoretical accounts of proximal motivation as well as help to improve degree programmes at universities and provide better career advice.

  4. Why do different people choose different university degrees? Motivation and the choice of degree.

    Science.gov (United States)

    Skatova, Anya; Ferguson, Eamonn

    2014-01-01

    Different people choose undergraduate degrees to study at university for different reasons. To date, there have been limited attempts to identify individual differences in motivation that drive undergraduate degree choice. We identified that people choose university degrees for four reasons: career concerns (Career), intrinsic interest in the subject (Interest), an opportunity to help others (Helping) and because they are looking for an easy option to get into higher education (Loafing). We investigated whether these motivations apply to the choice of undergraduate degree in two samples: (1) undergraduate (N = 989) and (2) prospective (N = 896) students. We developed the Motivations Influencing Course Choice (MICC) questionnaire to measure these motivations. Scales of Helping, Career, Loafing, and Interest showed good psychometric properties, showed validity with respect to general life goals and personality traits, and predicted actual and prospective degree choices. We demonstrated that medical degrees were chosen due to a mixture of Helping and Career, while engineering degrees were associated with Career and low Interest in the degree. The choice of arts and humanities degrees was driven by Interest and low concern about future career, accompanied with high Loafing. We also demonstrated gender differences: females were high in Helping (both samples) and Interest (only in the undergraduate sample) motivation, while males scored higher in Career (only in the undergraduate sample) and Loafing (both samples). The findings can feed into both theoretical accounts of proximal motivation as well as provide help to improve degree programmes at universities and support better career advice.

  5. Macroscopic damping model for zero degree energy distribution in ultra-relativistic heavy ion collisions

    International Nuclear Information System (INIS)

    Gao Chongshou; Wang Chengshing

    1993-01-01

    A macroscopic damping model is proposed to calculate the zero degree energy distribution in ultra-relativistic heavy ion collisions. The main features of the measured distributions are reproduced, good agreement is obtained in the middle energy region while overestimation results on the high energy side. The average energy loss coefficient of incident nucleons, varying in the reasonable region 0.2-0.6, depends on beam energy and target size

  6. Multiple Paths to Success: Degree Completion of 4-Year Starters Taking Various Pathways

    Science.gov (United States)

    Li, Dai

    2016-01-01

    With the use of data from the institutional research office at a comprehensive public 4-year university, this chapter describes an in-depth analysis of the institutional attendance, transfer, and graduation of three first-time student cohorts, revealing that not all types of multi-institutional attendance hurt degree completion, and strategic…

  7. An asymptotic formula for polynomials orthonormal with respect to a varying weight. II

    International Nuclear Information System (INIS)

    Komlov, A V; Suetin, S P

    2014-01-01

    This paper gives a proof of the theorem announced by the authors in the preceding paper with the same title. The theorem states that asymptotically the behaviour of the polynomials which are orthonormal with respect to the varying weight e −2nQ(x) p g (x)/√(∏ j=1 2p (x−e j )) coincides with the asymptotic behaviour of the Nuttall psi-function, which solves a special boundary-value problem on the relevant hyperelliptic Riemann surface of genus g=p−1. Here e 1 degree 2m and p g is a certain auxiliary polynomial of degree p−1. Bibliography: 23 titles

  8. Kinetics of swelling of polyelectrolyte gels: Fixed degree of ionization

    Science.gov (United States)

    Sen, Swati; Kundagrami, Arindam

    2015-12-01

    The swelling kinetics of uncharged and charged polymer (polyelectrolyte) gels in salt-free conditions is studied in one dimension by solving the constitutive equation of motion (Newton's law for the elementary gel volume) of the displacement variable by two theoretical methods: one in which the classical definition of stress is used with the bulk modulus taken as a parameter, and the other in which a phenomenological expression of the osmotic stress as a function of polymer density and degree of ionization is taken as an input to the dynamics. The time-evolution profiles for spatially varying polymer density and stress, along with the location of the gel-solvent interface, are obtained from the two methods. We show that both the polymer density (volume fraction) and stress inside the gel follow expected behaviours of being maximum for the uniformly shrunken gel, and relaxing slowly to the lowest values as the gel approaches equilibrium. We further show that, by comparing the temporal profiles of the gel-solvent interface and other variables between the two methods, one may attempt to assign an effective bulk modulus to the polyelectrolyte gel as a function of the degree of ionization and other parameters of the gel such as hydrophobicity, cross-link density, and the temperature. The major result we get is that the effective bulk modulus of a polyelectrolyte gel increases monotonically with its degree of ionization. In the process of identifying the parameters for a monotonic swelling, we calculated using a well-known expression of the free energy the equilibrium results of two-phase co-existence and the critical point of a polyelectrolyte gel with a fixed degree of ionization.

  9. Long-term acoustical observations of the mesopelagic fish Maurolicus muelleri reveal novel and varied vertical migration patterns

    KAUST Repository

    Staby, A; Rø stad, Anders; Kaartvedt, Stein

    2011-01-01

    . The data revealed known patterns as normal diel vertical migration (DVM), midnight sinking between dusk and dawn, and periods without migrations, as well as novel behaviours consisting of early morning ascents, reverse diel vertical migrations

  10. Quantifying Degree of Mastitis from Common Trends in a Panel of Indicators for Mastitis in Dairy Cows

    DEFF Research Database (Denmark)

    Højsgaard, S; Friggens, N C

    2010-01-01

    for such data and a corresponding method for estimating the DOI from a panel of indicators. An empirical proof of concept is provided. Using DOI, there was a significant difference between the DOI of mastitic and healthy control cows beginning 5 d before the mastitic cows were treated for mastitis.......This paper has 2 objectives. First, it argues that it is beneficial to regard degree of infection with respect to mastitis as a latent quantity varying continuously from 0 (truly healthy) to 1 (full-blown clinical mastitis). This quantity is denoted as degree of infection (DOI). The DOI is based...

  11. Dietary adaptation of FADS genes in Europe varied across time and geography.

    Science.gov (United States)

    Ye, Kaixiong; Gao, Feng; Wang, David; Bar-Yosef, Ofer; Keinan, Alon

    2017-05-26

    Fatty acid desaturase (FADS) genes encode rate-limiting enzymes for the biosynthesis of omega-6 and omega-3 long-chain polyunsaturated fatty acids (LCPUFAs). This biosynthesis is essential for individuals subsisting on LCPUFA-poor diets (for example, plant-based). Positive selection on FADS genes has been reported in multiple populations, but its cause and pattern in Europeans remain unknown. Here we demonstrate, using ancient and modern DNA, that positive selection acted on the same FADS variants both before and after the advent of farming in Europe, but on opposite (that is, alternative) alleles. Recent selection in farmers also varied geographically, with the strongest signal in southern Europe. These varying selection patterns concur with anthropological evidence of varying diets, and with the association of farming-adaptive alleles with higher FADS1 expression and thus enhanced LCPUFA biosynthesis. Genome-wide association studies reveal that farming-adaptive alleles not only increase LCPUFAs, but also affect other lipid levels and protect against several inflammatory diseases.

  12. A novel DFNB31 mutation associated with Usher type 2 syndrome showing variable degrees of auditory loss in a consanguineous Portuguese family.

    Science.gov (United States)

    Audo, Isabelle; Bujakowska, Kinga; Mohand-Saïd, Saddek; Tronche, Sophie; Lancelot, Marie-Elise; Antonio, Aline; Germain, Aurore; Lonjou, Christine; Carpentier, Wassila; Sahel, José-Alain; Bhattacharya, Shomi; Zeitz, Christina

    2011-01-01

    To identify the genetic defect of a consanguineous Portuguese family with rod-cone dystrophy and varying degrees of decreased audition. A detailed ophthalmic and auditory examination was performed on a Portuguese patient with severe autosomal recessive rod-cone dystrophy. Known genetic defects were excluded by performing autosomal recessive retinitis pigmentosa (arRP) genotyping microarray analysis and by Sanger sequencing of the coding exons and flanking intronic regions of eyes shut homolog-drosophila (EYS) and chromosome 2 open reading frame 71 (C2orf71). Subsequently, genome-wide homozygosity mapping was performed in DNA samples from available family members using a 700K single nucleotide polymorphism (SNP) microarray. Candidate genes present in the significantly large homozygous regions were screened for mutations using Sanger sequencing. The largest homozygous region (~11 Mb) in the affected family members was mapped to chromosome 9, which harbors deafness, autosomal recessive 31 (DFNB31; a gene previously associated with Usher syndrome). Mutation analysis of DFNB31 in the index patient identified a novel one-base-pair deletion (c.737delC), which is predicted to lead to a truncated protein (p.Pro246HisfsX13) and co-segregated with the disease in the family. Ophthalmic examination of the index patient and the affected siblings showed severe rod-cone dystrophy. Pure tone audiometry revealed a moderate hearing loss in the index patient, whereas the affected siblings were reported with more profound and early onset hearing impairment. We report a novel truncating mutation in DFNB31 associated with severe rod-cone dystrophy and varying degrees of hearing impairment in a consanguineous family of Portuguese origin. This is the second report of DFNB31 implication in Usher type 2.

  13. Degree of synchronization modulated by inhibitory neurons in clustered excitatory-inhibitory recurrent networks

    Science.gov (United States)

    Li, Huiyan; Sun, Xiaojuan; Xiao, Jinghua

    2018-01-01

    An excitatory-inhibitory recurrent neuronal network is established to numerically study the effect of inhibitory neurons on the synchronization degree of neuronal systems. The obtained results show that, with the number of inhibitory neurons and the coupling strength from an inhibitory neuron to an excitatory neuron increasing, inhibitory neurons can not only reduce the synchronization degree when the synchronization degree of the excitatory population is initially higher, but also enhance it when it is initially lower. Meanwhile, inhibitory neurons could also help the neuronal networks to maintain moderate synchronized states. In this paper, we call this effect as modulation effect of inhibitory neurons. With the obtained results, it is further revealed that the ratio of excitatory neurons to inhibitory neurons being nearly 4 : 1 is an economic and affordable choice for inhibitory neurons to realize this modulation effect.

  14. Estimation of time-varying reactivity by the H∞ optimal linear filter

    International Nuclear Information System (INIS)

    Suzuki, Katsuo; Shimazaki, Junya; Watanabe, Koiti

    1995-01-01

    The problem of estimating the time-varying net reactivity from flux measurements is solved for a point reactor kinetics model using a linear filtering technique in an H ∞ settings. In order to sue this technique, an appropriate dynamical model of the reactivity is constructed that can be embedded into the reactor model as one of its variables. A filter, which minimizes the H ∞ norm of the estimation error power spectrum, operates on neutron density measurements corrupted by noise and provides an estimate of the dynamic net reactivity. Computer simulations are performed to reveal the basic characteristics of the H ∞ optimal filter. The results of the simulation indicate that the filter can be used to determine the time-varying reactivity from neutron density measurements that have been corrupted by noise

  15. Temporal-varying failures of nodes in networks

    Science.gov (United States)

    Knight, Georgie; Cristadoro, Giampaolo; Altmann, Eduardo G.

    2015-08-01

    We consider networks in which random walkers are removed because of the failure of specific nodes. We interpret the rate of loss as a measure of the importance of nodes, a notion we denote as failure centrality. We show that the degree of the node is not sufficient to determine this measure and that, in a first approximation, the shortest loops through the node have to be taken into account. We propose approximations of the failure centrality which are valid for temporal-varying failures, and we dwell on the possibility of externally changing the relative importance of nodes in a given network by exploiting the interference between the loops of a node and the cycles of the temporal pattern of failures. In the limit of long failure cycles we show analytically that the escape in a node is larger than the one estimated from a stochastic failure with the same failure probability. We test our general formalism in two real-world networks (air-transportation and e-mail users) and show how communities lead to deviations from predictions for failures in hubs.

  16. Development of a Competency Mapping Tool for Undergraduate Professional Degree Programmes, Using Mechanical Engineering as a Case Study

    Science.gov (United States)

    Holmes, David W.; Sheehan, Madoc; Birks, Melanie; Smithson, John

    2018-01-01

    Mapping the curriculum of a professional degree to the associated competency standard ensures graduates have the competence to perform as professionals. Existing approaches to competence mapping vary greatly in depth, complexity, and effectiveness, and a standardised approach remains elusive. This paper describes a new mapping software tool that…

  17. Knowledge diffusion in complex networks by considering time-varying information channels

    Science.gov (United States)

    Zhu, He; Ma, Jing

    2018-03-01

    In this article, based on a model of epidemic spreading, we explore the knowledge diffusion process with an innovative mechanism for complex networks by considering time-varying information channels. To cover the knowledge diffusion process in homogeneous and heterogeneous networks, two types of networks (the BA network and the ER network) are investigated. The mean-field theory is used to theoretically draw the knowledge diffusion threshold. Numerical simulation demonstrates that the knowledge diffusion threshold is almost linearly correlated with the mean of the activity rate. In addition, under the influence of the activity rate and distinct from the classic Susceptible-Infected-Susceptible (SIS) model, the density of knowers almost linearly grows with the spreading rate. Finally, in consideration of the ubiquitous mechanism of innovation, we further study the evolution of knowledge in our proposed model. The results suggest that compared with the effect of the spreading rate, the average knowledge version of the population is affected more by the innovation parameter and the mean of the activity rate. Furthermore, in the BA network, the average knowledge version of individuals with higher degree is always newer than those with lower degree.

  18. Monitoring of 7Be in surface air of varying PM10 concentrations

    International Nuclear Information System (INIS)

    Chao, J.H.; Liu, C.C.; Cho, I.C.; Niu, H.

    2014-01-01

    In this study, beryllium-7 ( 7 Be) concentrations of surface air were monitored throughout a span of 23 years (1992–2012) in the Taiwanese cities Yilan, Taipei, Taichung, and Kaohsiung. During this period, particulate matter (PM) concentrations, in terms of PM 10 , were collected monthly from the nearest air-quality pollutant monitoring stations and compared against 7 Be concentrations. Seasonal monsoons influenced 7 Be concentrations in all cities, resulting in high winter and low summer concentrations. In addition, the meteorological conditions caused seasonal PM 10 variations, yielding distinct patterns among the cities. There was no correlation between 7 Be and PM 10 in the case cities. The average annual 7 Be concentrations varied little among the cities, ranging from 2.9 to 3.5 mBq/m 3 , while the PM 10 concentrations varied significantly from 38 μg/m 3 in Yilan to 92 μg/m 3 in Kaohsiung depending on the degree of air pollution and meteorological conditions. The correlation between the 7 Be concentration and gross-beta activities (A β ) in air implied that the 7 Be was mainly attached to crustal PM and its concentration varied little among the cities, regardless of the increase in anthropogenic PM in air-polluted areas. - Highlights: • Both 7 Be and PM 10 concentrations were monitored in four Taiwanese cities from 1992 to 2012. • Seasonal variations of 7 Be and PM 10 were explained based on on meteorological and pollution conditions. • The annual concentrations of 7 Be varied little among the four cities even in high PM environment. • 7 Be is believed to mainly attach to natural PM in the cities that exhibited varying PM 10 concentrations

  19. A microscopic study of the action of uranyl acetate on the erythrocyte at varying molarity and toxicity

    International Nuclear Information System (INIS)

    Wyatt, J.H.

    1977-03-01

    Phase contrast and dark field microphotographs were made to record variation of the shape and size changes seen when human erythrocytes are exposed in a number of ways to uranyl acetate in vitro. The degree of hemolysis produced by varying the toxicity of the uranyl acetate solutions was measured, and the results are discussed with particular reference to the possible influence of pH. (author)

  20. Clever strategists: Australian Magpies vary mobbing strategies, not intensity, relative to different species of predator

    Directory of Open Access Journals (Sweden)

    A Koboroff

    2013-03-01

    Full Text Available Anti-predator behaviour of magpies was investigated, using five species of model predators, at times of raising offspring. We predicted differences in mobbing strategies for each predator presented and also that raising juveniles would affect intensity of the mobbing event. Fourteen permanent resident family groups were tested using 5 different types of predator (avian and reptilian known to be of varying degrees of risk to magpies and common in their habitat. In all, 210 trials were conducted (across three different stages of juvenile development. We found that the stage of juvenile development did not alter mobbing behaviour significantly, but predator type did. Aerial strategies (such as swooping were elicited by taxidermic models of raptors, whereas a taxidermic model of a monitor lizard was approached on the ground and a model snake was rarely approached. Swooping patterns also changed according to which of the three raptors was presented. Our results show that, in contrast to findings in other species, magpies vary mobbing strategy depending on the predator rather than varying mobbing intensity.

  1. Clever strategists: Australian Magpies vary mobbing strategies, not intensity, relative to different species of predator.

    Science.gov (United States)

    Koboroff, A; Kaplan, G; Rogers, Lj

    2013-01-01

    Anti-predator behaviour of magpies was investigated, using five species of model predators, at times of raising offspring. We predicted differences in mobbing strategies for each predator presented and also that raising juveniles would affect intensity of the mobbing event. Fourteen permanent resident family groups were tested using 5 different types of predator (avian and reptilian) known to be of varying degrees of risk to magpies and common in their habitat. In all, 210 trials were conducted (across three different stages of juvenile development). We found that the stage of juvenile development did not alter mobbing behaviour significantly, but predator type did. Aerial strategies (such as swooping) were elicited by taxidermic models of raptors, whereas a taxidermic model of a monitor lizard was approached on the ground and a model snake was rarely approached. Swooping patterns also changed according to which of the three raptors was presented. Our results show that, in contrast to findings in other species, magpies vary mobbing strategy depending on the predator rather than varying mobbing intensity.

  2. Endothelial dysfunction in normoglycaemic first-degree relatives of type 2 diabetes mellitus complicated with hyperuricaemia.

    Science.gov (United States)

    Zhang, Junxia; Xiang, Lin; Zhang, Bilin; Cheng, Yangyang

    2017-03-01

    To reveal the effect of hyperuricaemia on endothelial function in normoglycaemic first-degree relatives of type 2 diabetes mellitus. In all, 40 first-degree relatives of type 2 diabetes mellitus with hyperuricaemia, 40 first-degree relatives of type 2 diabetes mellitus with normouricaemia and 35 healthy subjects without diabetic family history were recruited in this study. Anthropometric parameters as well as blood pressure, blood lipids, fasting blood glucose, fasting insulin, C-reactive protein, tumour necrosis factor-α and interleukin-6 were measured. Insulin resistance was assessed with homoeostasis model assessment index-insulin resistance index. To assess endothelial function, high-resolution ultrasonography was used for measuring flow- and nitroglycerine-mediated brachial artery vasodilation. When compared with control, flow-mediated dilation was lower in first-degree relatives with or without hyperuricaemia (both p type 2 diabetes mellitus (β = -0.677, p type 2 diabetes mellitus complicated with hyperuricaemia.

  3. Detection of random alterations to time-varying musical instrument spectra.

    Science.gov (United States)

    Horner, Andrew; Beauchamp, James; So, Richard

    2004-09-01

    The time-varying spectra of eight musical instrument sounds were randomly altered by a time-invariant process to determine how detection of spectral alteration varies with degree of alteration, instrument, musical experience, and spectral variation. Sounds were resynthesized with centroids equalized to the original sounds, with frequencies harmonically flattened, and with average spectral error levels of 8%, 16%, 24%, 32%, and 48%. Listeners were asked to discriminate the randomly altered sounds from reference sounds resynthesized from the original data. For all eight instruments, discrimination was very good for the 32% and 48% error levels, moderate for the 16% and 24% error levels, and poor for the 8% error levels. When the error levels were 16%, 24%, and 32%, the scores of musically experienced listeners were found to be significantly better than the scores of listeners with no musical experience. Also, in this same error level range, discrimination was significantly affected by the instrument tested. For error levels of 16% and 24%, discrimination scores were significantly, but negatively correlated with measures of spectral incoherence and normalized centroid deviation on unaltered instrument spectra, suggesting that the presence of dynamic spectral variations tends to increase the difficulty of detecting spectral alterations. Correlation between discrimination and a measure of spectral irregularity was comparatively low.

  4. Study of wavefront aberration in DR patients with different degree of dry eye

    Directory of Open Access Journals (Sweden)

    Jin-Ran Fang

    2018-05-01

    Full Text Available AIM: To compare the changes of wavefront aberrations in patients with diabetic retinopathy(DRand with different degrees of dry eye and to explore the reasons of visual quality decline in them. METHODS: We randomly selected 40 eyes in our hospital for treatment with DR and varying degrees of dry eye, and 40 eyes of normal control group. Topcon KR-1W visual quality analyzer was used to record the mean square the total high order corneal aberration, spherical aberration, comatic aberration and trefoil aberration of cornea with pupil diameters of 4mm and 6mm. Analysis of variance were used to compare the wavefront aberrations and the aberration values in the control group and in patients with diabetic retinopathy and with different degrees of dry eye. RESULTS: For 4mm and 6mm pupil diameters, nondiabetic retinopathy(NDRwith dry eye group, the nonproliferative diabetic retinopathy(NPDRwith dry eye group and proliferative diabetic retinopathy(PDRdry eye group had significantly increased tHOA, coma and trefoil compared with the contrast group(PPCONCLUSION: Dry eye of diabetic retinopathy with different degrees is closely related to the increase of wavefront aberration. Increased wavefront aberration may be one of the reasons to reduced visual quality in patients with diabetic retinopathy and with dry eye, and provide the basis for the decline of visual function of diabetic patients with dry eye.

  5. Identifying and Analyzing Strong Components of an Industrial Network Based on Cycle Degree

    Directory of Open Access Journals (Sweden)

    Zhiying Zhang

    2016-01-01

    Full Text Available In the era of big data and cloud computing, data research focuses not only on describing the individual characteristics but also on depicting the relationships among individuals. Studying dependence and constraint relationships among industries has aroused significant interest in the academic field. From the network perspective, this paper tries to analyze industrial relational structures based on cycle degree. The cycle degree of a vertex, that is, the number of cycles through a vertex in an industrial network, can describe the roles of the vertices of strong components in industrial circulation. In most cases, different vertices in a strong component have different cycle degrees, and the one with a larger cycle degree plays more important roles. However, the concept of cycle degree does not involve the lengths of the cycles, which are also important for circulations. The more indirect the relationship between two industries is, the weaker it is. In order to analyze strong components thoroughly, this paper proposes the concept of circular centrality taking into consideration the influence by two factors: the lengths and the numbers of cycles through a vertex. Exemplification indicates that a profound analysis of strong components in an industrial network can reveal the features of an economy.

  6. Cyclic efforts to improve completion rates of masters’ degree students in nursing

    Directory of Open Access Journals (Sweden)

    Lizeth Roets

    2012-12-01

    Full Text Available Supervisors at Higher Education Institutions are challenged to shorten throughput of Master’s degree students in nursing as researchers are needed to improve the art and science of the nursing profession. Globally the completion time for a postgraduate degree in the health sciences varies between 4.7 and 5.5 years. The purpose of the study was to describe strategies that were implemented to shorten completion time and attrition rate of postgraduate students. A cyclic technical, scientific collaborative mode within an action research methodology was used to identify factors impeding completion time in this study. Contrary to other studies, supervision was not an inhibiting factor in this study. Physical, technical, academic and financial aspects were identified by postgraduate students through questionnaires and informal discussion groups with supervisors as well as progress reports. Strategies were implemented to address these. Following implementation of all strategies, 42% of the postgraduate students in the School of Nursing completed their Master’s degree within two years. This implies a 34% improvement. Although the completion rate improved it was still unsatisfactory and new challenges were identified during the second cycle, for example, the number of inexperienced supervisors increased and they needed mentoring. Speed mentoring is a possible solution to the problem.

  7. Tendon material properties vary and are interdependent among turkey hindlimb muscles.

    Science.gov (United States)

    Matson, Andrew; Konow, Nicolai; Miller, Samuel; Konow, Pernille P; Roberts, Thomas J

    2012-10-15

    The material properties of a tendon affect its ability to store and return elastic energy, resist damage, provide mechanical feedback and amplify or attenuate muscle power. While the structural properties of a tendon are known to respond to a variety of stimuli, the extent to which material properties vary among individual muscles remains unclear. We studied the tendons of six different muscles in the hindlimb of Eastern wild turkeys to determine whether there was variation in elastic modulus, ultimate tensile strength and resilience. A hydraulic testing machine was used to measure tendon force during quasi-static lengthening, and a stress-strain curve was constructed. There was substantial variation in tendon material properties among different muscles. Average elastic modulus differed significantly between some tendons, and values for the six different tendons varied nearly twofold, from 829±140 to 1479±106 MPa. Tendons were stretched to failure, and the stress at failure, or ultimate tensile stress, was taken as a lower-limit estimate of tendon strength. Breaking tests for four of the tendons revealed significant variation in ultimate tensile stress, ranging from 66.83±14.34 to 112.37±9.39 MPa. Resilience, or the fraction of energy returned in cyclic length changes was generally high, and one of the four tendons tested was significantly different in resilience from the other tendons (range: 90.65±0.83 to 94.02±0.71%). An analysis of correlation between material properties revealed a positive relationship between ultimate tensile strength and elastic modulus (r(2)=0.79). Specifically, stiffer tendons were stronger, and we suggest that this correlation results from a constrained value of breaking strain, which did not vary significantly among tendons. This finding suggests an interdependence of material properties that may have a structural basis and may explain some adaptive responses observed in studies of tendon plasticity.

  8. PMMA-g-OEtOx Graft Copolymers: Influence of Grafting Degree and Side Chain Length on the Conformation in Aqueous Solution

    Directory of Open Access Journals (Sweden)

    Irina Muljajew

    2018-03-01

    Full Text Available Depending on the degree of grafting (DG and the side chain degree of polymerization (DP, graft copolymers may feature properties similar to statistical copolymers or to block copolymers. This issue is approached by studying aqueous solutions of PMMA-g-OEtOx graft copolymers comprising a hydrophobic poly(methyl methacrylate (PMMA backbone and hydrophilic oligo(2-ethyl-2-oxazoline (OEtOx side chains. The graft copolymers were synthesized via reversible addition-fragmentation chain transfer (RAFT copolymerization of methyl methacrylate (MMA and OEtOx-methacrylate macromonomers of varying DP. All aqueous solutions of PMMA-g-OEtOx (9% ≤ DG ≤ 34%; 5 ≤ side chain DP ≤ 24 revealed lower critical solution temperature behavior. The graft copolymer architecture significantly influenced the aggregation behavior, the conformation in aqueous solution and the coil to globule transition, as verified by means of turbidimetry, dynamic light scattering, nuclear magnetic resonance spectroscopy, and analytical ultracentrifugation. The aggregation behavior of graft copolymers with a side chain DP of 5 was significantly affected by small variations of the DG, occasionally forming mesoglobules above the cloud point temperature (Tcp, which was around human body temperature. On the other hand, PMMA-g-OEtOx with elongated side chains assembled into well-defined structures below the Tcp (apparent aggregation number (Nagg = 10 that were able to solubilize Disperse Orange 3. The thermoresponsive behavior of aqueous solutions thus resembled that of micelles comprising a poly(2-ethyl-2-oxazoline (PEtOx shell (Tcp > 60 °C.

  9. HRD Degrees.

    Science.gov (United States)

    Geber, Beverly

    1987-01-01

    The author describes the growing movement toward accreditation for human resources development professionals. She covers the issue of diversity, undergraduate versus graduate degrees, and future trends. (CH)

  10. HadISST (1-degree)/HadISST (1-degree)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Monthly version of HadISST sea surface temperature component (1-degree). See Rayner, N. A., Parker, D. E., Horton, E. B., Folland, C. K., Alexander, L. V., Rowell,...

  11. Time-varying causal network of the Korean financial system based on firm-specific risk premiums

    Science.gov (United States)

    Song, Jae Wook; Ko, Bonggyun; Cho, Poongjin; Chang, Woojin

    2016-09-01

    The aim of this paper is to investigate the Korean financial system based on time-varying causal network. We discover many stylized facts by utilizing the firm-specific risk premiums for measuring the causality direction from a firm to firm. At first, we discover that the interconnectedness of causal network is affected by the outbreak of financial events; the co-movement of firm-specific risk premium is strengthened after each positive event, and vice versa. Secondly, we find that the major sector of the Korean financial system is the Depositories, and the financial reform in June-2011 achieves its purpose by weakening the power of risk-spillovers of Broker-Dealers. Thirdly, we identify that the causal network is a small-world network with scale-free topology where the power-law exponents of out-Degree and negative event are more significant than those of in-Degree and positive event. Lastly, we discuss that the current aspects of causal network are closely related to the long-term future scenario of the KOSPI Composite index where the direction and stability are significantly affected by the power of risk-spillovers and the power-law exponents of degree distributions, respectively.

  12. Set our Master's degrees free

    Science.gov (United States)

    Padman, Rachael

    2010-04-01

    Making UK undergraduate physics degrees longer must have seemed like a good idea at the time. Back in the early 1990s the standard three-year Bachelor's physics degree (four years in Scotland) was under pressure at both ends. The A-level curriculum - one of the requirements for entry onto a degree course - was being increasingly modularized, and dumbed down. Physics students were arriving at university less well prepared than in the past and there was an increasing awareness that graduates of five-year continental degree courses were better equipped for a professional scientific career than those in the UK. At the same time, local education authorities in the UK were required to provide full funding for a first degree, whether for three or four years.

  13. Phase-dependent dynamic potential of magnetically coupled two-degree-of-freedom bistable energy harvester.

    Science.gov (United States)

    Kim, Pilkee; Nguyen, Minh Sang; Kwon, Ojin; Kim, Young-Jin; Yoon, Yong-Jin

    2016-09-28

    A system of magnetically coupled oscillators has been recently considered as a promising compact structure to integrate multiple bistable energy harvesters (BEHs), but its design is not straightforward owing to its varying potential energy pattern, which has not been understood completely yet. This study introduces the concept of phase-dependent dynamic potential in a magnetically coupled BEH system with two degrees of freedom (DOFs) to explain the underlying principle of the complicated dynamics of the system. Through theoretical simulations and analyses, two distinct dynamic regimes, called the out-of-phase and in-phase mode regimes in this report, are found to exist in the frequency regions of the 1 st and 2 nd primary intrawell resonances. For the out-of-phase mode regime, the frequency displacement (and output power) responses of the 2-DOF BEH system exhibit typical double-well dynamics, whereas for the in-phase mode regime, only single-well dynamics is observed though the system is statically bistable. These dynamic regimes are also revealed to be caused by the difference in the dynamic potential energy trajectories propagating on a high-dimensional potential energy surface. The present approach to the dynamics of the 2-DOF BEH system can be extended and applied to higher-DOF systems, which sheds light on compact and efficient designs of magnetically coupled BEH chain structures.

  14. Perceived Mathematical Ability under Challenge: A Longitudinal Perspective on Sex Segregation among STEM Degree Fields

    Directory of Open Access Journals (Sweden)

    Samantha eNix

    2015-06-01

    Full Text Available Students’ perceptions of their mathematics ability vary by gender and seem to influence science, technology, engineering, and math (STEM degree choice. Related, students’ perceptions during academic difficulty are increasingly studied in educational psychology, suggesting a link between such perceptions and task persistence. Despite interest in examining the gender disparities in STEM, these concepts have not been considered in tandem. We investigate how perceived ability under challenge – in particular in mathematics domains – influences entry into the most sex-segregated and mathematics-intensive undergraduate degrees: physics, engineering, mathematics, and computer science (PEMC. Using nationally representative Education Longitudinal Study of 2002 (ELS data, we estimate the influence of perceived ability under challenging conditions on advanced high school science course taking, selection of an intended STEM major, and specific major type two years after high school. Demonstrating the importance of specificity when discussing how gender influences STEM career pathways, the intersecting effects of gender and perceived ability under mathematics challenge were distinct for each scientific major category. Perceived ability under challenge in secondary school varied by gender, and was highly predictive of selecting PEMC and health sciences majors. Notably, women’s 12th grade perceptions of their ability under mathematics challenge increased the probability that they would select PEMC majors, increasing women's probability of selecting PEMC over and above biology. In addition, gender moderated the effect of growth mindset on students’ selection of health science majors. The implications of these results are discussed, with particular attention to access to advanced scientific coursework in high school and interventions aimed at enhancing young women’s perceptions of their ability to facilitate their pathways to scientific degrees.

  15. Opposite Degree Algorithm and Its Applications

    Directory of Open Access Journals (Sweden)

    Xiao-Guang Yue

    2015-12-01

    Full Text Available The opposite (Opposite Degree, referred to as OD algorithm is an intelligent algorithm proposed by Yue Xiaoguang et al. Opposite degree algorithm is mainly based on the concept of opposite degree, combined with the idea of design of neural network and genetic algorithm and clustering analysis algorithm. The OD algorithm is divided into two sub algorithms, namely: opposite degree - numerical computation (OD-NC algorithm and opposite degree - Classification computation (OD-CC algorithm.

  16. Study of composition of espresso coffee prepared from various roast degrees of Coffea arabica L. coffee beans.

    Science.gov (United States)

    Kučera, Lukáš; Papoušek, Roman; Kurka, Ondřej; Barták, Petr; Bednář, Petr

    2016-05-15

    Espresso coffee samples prepared at various roasting degrees defined according to its basic conventional classification (light, medium, medium-dark and dark roasted) were analyzed by ultra-performance liquid chromatography/tandem mass spectrometry. Obtained raw data were processed using multivariate statistical analysis (Principal Component Analysis, PCA) to evaluate chemical differences between each roasting degrees (untargeted part of study). All four roasting degrees were resolved in appropriate Score plot. Orthogonal Projections to Latent Structures provided signals of significant markers describing the differences among particular roasting degrees. Detailed interpretation of those signals by targeted LC/MS(2) analysis revealed four groups of compounds. The first two groups involve chlorogenic acids and related lactones. The signals of other two sets of markers were ascribed to some specific atractylosides and particular melanoidins. Ratios of contents of selected representatives of each group to the sum of all identified markers were proposed as definite parameters for determination of roasting degree of Brazilian coffee Arabica. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Feedback topology and XOR-dynamics in Boolean networks with varying input structure.

    Science.gov (United States)

    Ciandrini, L; Maffi, C; Motta, A; Bassetti, B; Cosentino Lagomarsino, M

    2009-08-01

    We analyze a model of fixed in-degree random Boolean networks in which the fraction of input-receiving nodes is controlled by the parameter gamma. We investigate analytically and numerically the dynamics of graphs under a parallel XOR updating scheme. This scheme is interesting because it is accessible analytically and its phenomenology is at the same time under control and as rich as the one of general Boolean networks. We give analytical formulas for the dynamics on general graphs, showing that with a XOR-type evolution rule, dynamic features are direct consequences of the topological feedback structure, in analogy with the role of relevant components in Kauffman networks. Considering graphs with fixed in-degree, we characterize analytically and numerically the feedback regions using graph decimation algorithms (Leaf Removal). With varying gamma , this graph ensemble shows a phase transition that separates a treelike graph region from one in which feedback components emerge. Networks near the transition point have feedback components made of disjoint loops, in which each node has exactly one incoming and one outgoing link. Using this fact, we provide analytical estimates of the maximum period starting from topological considerations.

  18. Feedback topology and XOR-dynamics in Boolean networks with varying input structure

    Science.gov (United States)

    Ciandrini, L.; Maffi, C.; Motta, A.; Bassetti, B.; Cosentino Lagomarsino, M.

    2009-08-01

    We analyze a model of fixed in-degree random Boolean networks in which the fraction of input-receiving nodes is controlled by the parameter γ . We investigate analytically and numerically the dynamics of graphs under a parallel XOR updating scheme. This scheme is interesting because it is accessible analytically and its phenomenology is at the same time under control and as rich as the one of general Boolean networks. We give analytical formulas for the dynamics on general graphs, showing that with a XOR-type evolution rule, dynamic features are direct consequences of the topological feedback structure, in analogy with the role of relevant components in Kauffman networks. Considering graphs with fixed in-degree, we characterize analytically and numerically the feedback regions using graph decimation algorithms (Leaf Removal). With varying γ , this graph ensemble shows a phase transition that separates a treelike graph region from one in which feedback components emerge. Networks near the transition point have feedback components made of disjoint loops, in which each node has exactly one incoming and one outgoing link. Using this fact, we provide analytical estimates of the maximum period starting from topological considerations.

  19. On the relationship between degree of hand-preference and degree of language lateralization

    NARCIS (Netherlands)

    Somers, Metten; Ophoff, Roel A; Boks, Marco P; Fleer, Willemien; de Visser, Kees C L; Kahn, René S; Sommer, Iris E; Aukes, M.F.

    2015-01-01

    Language lateralization and hand-preference show inter-individual variation in the degree of lateralization to the left- or right, but their relation is not fully understood. Disentangling this relation could aid elucidating the mechanisms underlying these traits. The relation between degree of

  20. Pions and other hadronic degrees of freedom in nuclei

    International Nuclear Information System (INIS)

    Brockmann, B.; Weise, W.

    1985-01-01

    As ≥E and or ≥q is increased up to several hundreds of MeV, the explicit mesonic degrees of freedom become directly visible. The pion, in particular, is of fundamental importance. With its small mass of m/sub π/ = 140 MeV it is by far the lightest of all mesons. It is the generator of the long range nucleon-nucleon interaction. The pion Compton wavelength psi/sub π/ = Κm/sub π/c = 1.4 fm, defines the length scale of nuclear physics. As mesons become important, nucleons begin to reveal their intrinsic structure. Inseparably connected with pionic degrees of freedom is the role of the Δ(1232), the spin 3/2-isopin 3/2 isobar reached from the nucleon by a strong spin-isopin transition at an excitation energy ΔE = M/sub Δ/ - M ≅ 300 MeV, the Δ-nucleon mass difference. This paper, the position is taken that the nucleus consists of nucleons and their excited states (primarily the ≥ (1232)) which communicate by exchange of mesons (in particular: the pion). Such a description has turned out to be quite successful in correlating various phenomena and data at intermediate energies, remarkably though without the need, so far, for explicit reference to underlying quark degrees of freedom. This progress has gone parallel with the similarly successful meson exchange phenomenology of nucleon-nucleon forces at long and intermediate distances (r ≥ 0.8 fm)

  1. [Preparation of the graduation dissertation at bachelor degree, a fruitful time for acquiring methodological competence: research regarding graduate satisfaction].

    Science.gov (United States)

    Monaco, Rita Ester; Roccu, Mariangela; Pazzaglini, Annarita

    2008-01-01

    To sphere the plan for formative quality improvement a course at bachelor degree, II Faculty of Medicine and Surgery La Sapienza of Rome, Study Center St. John of God FBF, has started a plan hinged various levels. To revisit the regulation of a school regarding DM 3 November 1999 n. 509 and to Dm 22 October 2004 n 270; To specify an evaluation standard a varied typology of the graduation dissertation; To plan a student guide for the drawing up of the graduation dissertation a bachelor degree; To value a graduate's satisfaction. The article explains the plan of a specific evaluation standard, the plan is a student guide drawn up for the graduation dissertation at bachelor degree; and the results of the known research about the graduate 's satisfaction.

  2. Cluster analysis as a tool of guests segmentation by the degree of their demand

    Directory of Open Access Journals (Sweden)

    Damijan Mumel

    2002-01-01

    Full Text Available Authors demonstrate the use of cluster analysis in finding out (ascertaining the homogenity/heterogenity of guests as to the degree of their demand. The degree of guests’ demand is defined according to the importance of perceived service quality components measured by SERVQUAL, which was adopted and adapted, according to the specifics of health spa industry in Slovenia. Goals of the article are: (a the identification of the profile of importance of general health spa service quality components, and (b the identification of groups of guests (segments according to the degree of their demand in the research in 1991 compared with 1999. Cluster analysis serves as useful tool for guest segmentation since it reveals the existence of important differences in the structure of guests in the year 1991 compared with the year 1999. The results serve as a useful database for management in health spas.

  3. Diploma to degree 1976 to 1993

    International Nuclear Information System (INIS)

    Price, Richard

    2009-01-01

    The debate on degree education for radiographers began in earnest in the mid-1970s. Initially the debate hinged around whether a degree education was necessary for radiographers. One argument was that it was felt that a degree would separate academic and clinical training but eventually when degrees were introduced practical skills were assessed formally for the first time; something that had not been achieved with the Diploma of the College of Radiographers (DCR). The DCR itself became a barrier to degree education as the College of Radiographers (CoR) insisted that it was the only qualification recognised for state registration and as such would have to remain embedded as a distinct qualification within a degree. A major breakthrough came when the Council for National Academic Awards (CNAA) recognised the DCR at the same level as an ordinary degree. Around the same time the CoR published its Degree Rationale which announced a change in policy by not insisting that the DCR was sacrosanct. Developments followed rapidly and the first honours degree in radiography was validated in 1989 despite opposition from scientific officers at the Department of Health. Degrees were approved for state registration and radiography became a graduate profession by 1993 following years of debate and after overcoming opposition from both within and external to the profession.

  4. Fracture toughness testing of V-4Cr-4Ti at 25{degrees}C and -196{degrees}C

    Energy Technology Data Exchange (ETDEWEB)

    Li, H.X.; Kurtz, R.J. [Pacific Northwest National Lab., Richland, WA (United States)

    1996-10-01

    Measurements of the fracture toughness of the production-scale heat (832665) of V-4Cr-4Ti have been performed at 25{degrees}C and {minus}196{degrees}C using compact tension (CT) specimens. Test specimens were vacuum annealed at either 1000{degrees}C for 1 hour (HT1) or 1050{degrees}C for two hours (HT2). Specimens given the HT1 treatment were annealed after final machining, whereas the HT2 specimens received the 1050{degrees}C anneal at Teledyne Wah Chang prior to final machining. Following machining HT2 specimens were then vacuum annealed at 180{degrees}C for two hours to remove hydrogen. Specimens treated using HT1 had a partially recrystallized microstructure and those treated using HT2 had a fully recrystallized microstructure. The fracture toughness at 25{degrees}C was determined by J-integral tests and at {minus}196{degrees}C by ASTM E 399 type tests. Toughness values obtained at {minus}196{degrees}C were converted to J-integral values for comparison to the 25{degrees}C data. The 25{degrees}C fracture toughness was very high with none of the specimens giving valid results per ASTM criteria. Specimens fractured by microvoid coalescence. The fracture toughness at {minus}196{degrees}C was much lower than that at 25{degrees}C and the fracture surface showed predominantly cleavage features. The present results show a transition from ductile to brittle behavior with decreasing test temperature which is not observed from one-third scale Charpy impact tests. The fracture toughness at {minus}196{degrees}C was still quite high, however, at about 75 kJ/m{sup 2}. Delaminations in planes normal to the thickness direction were seen at both test temperatures. Fracture surfaces inside the delaminations exhibited nearly 100% cleavage facets. The cause of the brittle delaminations was not determined, but will be a subject for further investigation.

  5. Superheated emulsions in neutron spectrometry by varying ambient pressure

    International Nuclear Information System (INIS)

    Das, Mala; Sawamura, Teruko

    2005-01-01

    The principle of present work lies on the dependence of the threshold neutron energy on the dimensionless quantity ''degree of metastability (ss)'' of superheated liquids. The response of the superheated emulsions consists of the drops of superheated liquid (C 2 Cl 2 F 4 , b.p. 3.77 deg. C) has been measured at different 'ss' by varying ambient pressure at different temperatures, in the presence of neutrons generated in Pb by a (γ,n) reaction from 45 MeV electron LINAC of Hokkaido University. To unfold the neutron energy spectrum, a relationship has been developed between the 'ss' of superheated liquids and the threshold neutron energy. The spectrum at the detector position has been calculated by the MCNP code and a comparison has been made with the experimental spectrum. The utilisation of 'ss' is more flexible as this relation can be applied to both positive and negative ambient pressures as well as at different ambient temperatures

  6. Comparison of two-stage thermophilic (68 degrees C/55 degrees C) anaerobic digestion with one-stage thermophilic (55 degrees C) digestion of cattle manure

    DEFF Research Database (Denmark)

    Nielsen, H.B.; Mladenovska, Zuzana; Westermann, Peter

    2004-01-01

    A two-stage 68degreesC/55degreesC anaerobic degradation process for treatment of cattle manure was studied. In batch experiments, an increase of the specific methane yield, ranging from 24% to 56%, was obtained when cattle manure and its fractions (fibers and liquid) were pretreated at 68degrees......, was compared with a conventional single-stage reactor running at 55degreesC with 15-days HRT. When an organic loading of 3 g volatile solids (VS) per liter per day was applied, the two-stage setup had a 6% to 8% higher specific methane yield and a 9% more effective VS-removal than the conventional single......-stage reactor. The 68degreesC reactor generated 7% to 9% of the total amount of methane of the two-stage system and maintained a volatile fatty acids (VFA) concentration of 4.0 to 4.4 g acetate per liter. Population size and activity of aceticlastic methanogens, syntrophic bacteria, and hydrolytic...

  7. Gas metal arc welding of butt joint with varying gap width based on neural networks

    DEFF Research Database (Denmark)

    Christensen, Kim Hardam; Sørensen, Torben

    2005-01-01

    penetration, when the gap width is varying during the welding process. The process modeling to facilitate the mapping from joint geometry and reference weld quality to significant welding parameters, has been based on a multi-layer feed-forward network. The Levenberg-Marquardt algorithm for non-linear least......This paper describes the application of the neural network technology for gas metal arc welding (GMAW) control. A system has been developed for modeling and online adjustment of welding parameters, appropriate to guarantee a certain degree of quality in the field of butt joint welding with full...

  8. Globally exponential stability condition of a class of neural networks with time-varying delays

    International Nuclear Information System (INIS)

    Liao, T.-L.; Yan, J.-J.; Cheng, C.-J.; Hwang, C.-C.

    2005-01-01

    In this Letter, the globally exponential stability for a class of neural networks including Hopfield neural networks and cellular neural networks with time-varying delays is investigated. Based on the Lyapunov stability method, a novel and less conservative exponential stability condition is derived. The condition is delay-dependent and easily applied only by checking the Hamiltonian matrix with no eigenvalues on the imaginary axis instead of directly solving an algebraic Riccati equation. Furthermore, the exponential stability degree is more easily assigned than those reported in the literature. Some examples are given to demonstrate validity and excellence of the presented stability condition herein

  9. Constraining the roughness degree of slip heterogeneity

    KAUST Repository

    Causse, Mathieu

    2010-05-07

    This article investigates different approaches for assessing the degree of roughness of the slip distribution of future earthquakes. First, we analyze a database of slip images extracted from a suite of 152 finite-source rupture models from 80 events (Mw = 4.1–8.9). This results in an empirical model defining the distribution of the slip spectrum corner wave numbers (kc) as a function of moment magnitude. To reduce the “epistemic” uncertainty, we select a single slip model per event and screen out poorly resolved models. The number of remaining models (30) is thus rather small. In addition, the robustness of the empirical model rests on a reliable estimation of kc by kinematic inversion methods. We address this issue by performing tests on synthetic data with a frequency domain inversion method. These tests reveal that due to smoothing constraints used to stabilize the inversion process, kc tends to be underestimated. We then develop an alternative approach: (1) we establish a proportionality relationship between kc and the peak ground acceleration (PGA), using a k−2 kinematic source model, and (2) we analyze the PGA distribution, which is believed to be better constrained than slip images. These two methods reveal that kc follows a lognormal distribution, with similar standard deviations for both methods.

  10. Lichen Persistence and Recovery in Response to Varied Volcanic Disturbances

    Science.gov (United States)

    Nelson, P.; Wheeler, T. B.

    2015-12-01

    Volcanic eruptions produce many ecological disturbances that structure vegetation. While lichens are sensitive to disturbances, little is known about their responses to volcanic disturbances, except for colonization of lava. We examined lichen community responses through time to different disturbances produced by the May 1, 2008 eruption of Volcan Chaiten in south-central Chile. Pre-eruption vegetation near the volcano was old-growth Valdivian temperate rainforest dominated by closed-canopy Nothofagus sp... In 2012, we installed thirteen 1-acre plots across volcanic disturbance zones on which a time-constrained search was done for all macrolichen species, each of which was assigned an approximate log10 categorical abundance. We also installed a 0.2 m2 quadrat on two representative trees per plot for repeat photography of lichen cover. We remeasured at least one plot per disturbance zone in 2014 and re-photographed tree quadrats in 2013 and 2014. We then analyzed species composition and abundance differences among disturbance zones. In 2012, the blast (pyroclastic density flow), scorch (standing scorched forest at the edge of the blast) and deep tephra (>10 cm) zones had the lowest lichen species richness (5-13 species), followed by reference (unimpacted) and shallow (lichen species since 2012 while the light tephra and reference were essentially unchanged. Gravel rain, gravel rain + pumice and flooded forest plots all had about the same number of species in 2014 as 2012. Lichen colonization and growth in tree quadrats varied widely, from very little colonization in the blast to prolific colonization in the gravel rain + pumice zone. Lichen's varied responses to different volcanic disturbances were attributable to varying degrees of mortality and subsequent availability of substrate, quantity of light and removal of competitors. While sensitive to disturbance, lichens are apparently resilient to and can quickly recolonize after a variety of large, violent volcanic

  11. Perception and description of premium beers by panels with different degrees of product expertise

    DEFF Research Database (Denmark)

    Giacalone, Davide; Ribeiro, Leticia Machado; Frøst, Michael Bom

    2016-01-01

    The present study compares subjects with varying degrees of product expertise with regards to their ability to provide a sensory profile of beverages. Eight premium beers were evaluated by three different panels using a Napping® test, followed by a descriptive task. Two panels were constituted of...... were all above 0.90, indicating high configurational similarity. In contrast, PLS-DA showed significant differences in the use of attributes, particularly between Experts and Novices, suggesting that product expertise is more associated with descriptive, rather than perceptual, ability....

  12. The Kilo-Degree Survey

    NARCIS (Netherlands)

    de Jong, J. T. A.; Kuijken, K.; Applegate, D.; Begeman, K.; Belikov, A.; Blake, C.; Bout, J.; Boxhoorn, D.; Buddelmeijer, H.; Buddendiek, A.; Cacciato, M.; Capaccioli, M.; Choi, A.; Cordes, O.; Covone, G.; Dall'Ora, M.; Edge, A.; Erben, T.; Franse, J.; Getman, F.; Grado, A.; Harnois-Deraps, J.; Helmich, E.; Herbonnet, R.; Heymans, C.; Hildebrandt, H.; Hoekstra, H.; Huang, Z.; Irisarri, N.; Joachimi, B.; Köhlinger, F.; Kitching, T.; La Barbera, F.; Lacerda, P.; McFarland, J.; Miller, L.; Nakajima, R.; Napolitano, N. R.; Paolillo, M.; Peacock, J.; Pila-Diez, B.; Puddu, E.; Radovich, M.; Rifatto, A.; Schneider, P.; Schrabback, T.; Sifon, C.; Sikkema, G.; Simon, P.; Sutherland, W.; Tudorica, A.; Valentijn, E.; van der Burg, R.; van Uitert, E.; van Waerbeke, L.; Velander, M.; Kleijn, G. V.; Viola, M.; Vriend, W.-J.

    2013-01-01

    The Kilo-Degree Survey (KiDS), a 1500-square-degree optical imaging survey with the recently commissioned OmegaCAM wide-field imager on the VLT Survey Telescope (VST), is described. KiDS will image two fields in u-,g-,r- and i-bands and, together with the VIKING survey, produce nine-band (u- to

  13. Varying Influence of Different Forcings on the Indo-Pacific Warm Pool Climate

    Science.gov (United States)

    Mohtadi, M.; Huang, E.; Hollstein, M.; Chen, Y.; Schefuß, E.; Rosenthal, Y.; Prange, M.; Oppo, D.; Liu, J.; Steinke, S.; Martinez-Mendez, G.; Tian, J.; Moffa-Sanchez, P.; Lückge, A.

    2017-12-01

    Proxy records of rainfall in marine archives from the eastern and western parts of the Indo-Pacific Warm Pool (IPWP) vary at precessional band and suggest a dominant role of orbital forcing by modulating monsoon rainfall and the position of the Inter Tropical Convergence Zone. Rainfall changes recorded in marine archives from the northern South China Sea reveal a more complex history. They are largely consistent with those recorded in the Chinese cave speleothems during glacial periods, but show opposite changes during interglacial peaks that coincide with strong Northern Hemisphere summer insolation maxima. During glacial periods, the establishment of massive Northern Hemisphere ice sheets and the exposure of broad continental shelves in East and Southeast Asia alter the large-scale routes and amounts of water vapor transport onto land relative to interglacials. Precipitation over China during glacials varies at precessional band and is dominated by water vapor transport from the nearby tropical and northwest Pacific, resulting in consistent changes in precipitation over large areas. In the absence of ice forcing during peak interglacials with a strong summer insolation, the low-level southerly monsoonal winds mainly of the Indian Ocean origin penetrate further landward and rainout along their path over China. Subsurface temperatures from the IPWP lack changes on glacial-interglacial timescales but follow the obliquity cycle, and suggest that obliquity-paced climate variations at mid-latitudes remotely control subsurface temperatures in the IPWP. Temperature and rainfall in the IPWP respond primarily to abrupt climate changes in the North Atlantic on millennial timescales, and to ENSO and solar forcing on interannual to decadal timescales. In summary, results from marine records reveal that the IPWP climate is sensitive to changes in spatial and temporal distribution of heat by many types of forcing, the influence of which seems to vary in time and space.

  14. Exposure to time varying magnetic fields associated with magnetic resonance imaging reduces fentanyl-induced analgesia in mice

    Energy Technology Data Exchange (ETDEWEB)

    Teskey, G.C.; Prato, F.S.; Ossenkopp, K.P.; Kavaliers, M.

    1988-01-01

    The effects of exposure to clinical magnetic resonance imaging (MRI) on analgesia induced by the mu opiate agonist, fentanyl, was examined in mice. During the dark period, adult male mice were exposed for 23.2 min to the time-varying (0.6 T/sec) magnetic field (TVMF) component of the MRI procedure. Following this exposure, the analgesic potency of fentanyl citrate (0.1 mg/kg) was determined at 5, 10, 15, and 30 min post-injection, using a thermal test stimulus (hot-plate 50 degrees C). Exposure to the magnetic-field gradients attenuated the fentanyl-induced analgesia in a manner comparable to that previously observed with morphine. These results indicate that the time-varying magnetic fields associated with MRI have significant inhibitory effects on the analgesic effects of specific mu-opiate-directed ligands.

  15. Development of a competency mapping tool for undergraduate professional degree programmes, using mechanical engineering as a case study

    Science.gov (United States)

    Holmes, David W.; Sheehan, Madoc; Birks, Melanie; Smithson, John

    2018-01-01

    Mapping the curriculum of a professional degree to the associated competency standard ensures graduates have the competence to perform as professionals. Existing approaches to competence mapping vary greatly in depth, complexity, and effectiveness, and a standardised approach remains elusive. This paper describes a new mapping software tool that streamlines and standardises the competency mapping process. The available analytics facilitate ongoing programme review, management, and accreditation. The complete mapping and analysis of an Australian mechanical engineering degree programme is described as a case study. Each subject is mapped by evaluating the amount and depth of competence development present. Combining subject results then enables highly detailed programme level analysis. The mapping process is designed to be administratively light, with aspects of professional development embedded in the software. The effective competence mapping described in this paper enables quantification of learning within a professional degree programme, and provides a mechanism for holistic programme improvement.

  16. Holographic cinematography of time-varying reflecting and time-varying phase objects using a Nd:YAG laser

    Science.gov (United States)

    Decker, A. J.

    1982-01-01

    The use of a Nd:YAG laser to record holographic motion pictures of time-varying reflecting objects and time-varying phase objects is discussed. Sample frames from both types of holographic motion pictures are presented. The holographic system discussed is intended for three-dimensional flow visualization of the time-varying flows that occur in jet-engine components.

  17. Perceived mathematical ability under challenge: a longitudinal perspective on sex segregation among STEM degree fields.

    Science.gov (United States)

    Nix, Samantha; Perez-Felkner, Lara; Thomas, Kirby

    2015-01-01

    Students' perceptions of their mathematics ability vary by gender and seem to influence science, technology, engineering, and mathematics (STEM) degree choice. Related, students' perceptions during academic difficulty are increasingly studied in educational psychology, suggesting a link between such perceptions and task persistence. Despite interest in examining the gender disparities in STEM, these concepts have not been considered in tandem. In this manuscript, we investigate how perceived ability under challenge-in particular in mathematics domains-influences entry into the most sex-segregated and mathematics-intensive undergraduate degrees: physics, engineering, mathematics, and computer science (PEMC). Using nationally representative Education Longitudinal Study of 2002 (ELS) data, we estimate the influence of perceived ability under challenging conditions on advanced high school science course taking, selection of an intended STEM major, and specific major type 2 years after high school. Demonstrating the importance of specificity when discussing how gender influences STEM career pathways, the intersecting effects of gender and perceived ability under mathematics challenge were distinct for each scientific major category. Perceived ability under challenge in secondary school varied by gender, and was highly predictive of selecting PEMC and health sciences majors. Notably, women's 12th grade perceptions of their ability under mathematics challenge increased their probability of selecting PEMC majors over and above biology. In addition, gender moderated the effect of growth mindset on students' selection of health science majors. Perceptions of ability under challenge in general and verbal domains also influenced retention in and declaration of certain STEM majors. The implications of these results are discussed, with particular attention to access to advanced scientific coursework in high school and interventions aimed at enhancing young women's perceptions of

  18. Perceived mathematical ability under challenge: a longitudinal perspective on sex segregation among STEM degree fields

    Science.gov (United States)

    Nix, Samantha; Perez-Felkner, Lara; Thomas, Kirby

    2015-01-01

    Students' perceptions of their mathematics ability vary by gender and seem to influence science, technology, engineering, and mathematics (STEM) degree choice. Related, students' perceptions during academic difficulty are increasingly studied in educational psychology, suggesting a link between such perceptions and task persistence. Despite interest in examining the gender disparities in STEM, these concepts have not been considered in tandem. In this manuscript, we investigate how perceived ability under challenge—in particular in mathematics domains—influences entry into the most sex-segregated and mathematics-intensive undergraduate degrees: physics, engineering, mathematics, and computer science (PEMC). Using nationally representative Education Longitudinal Study of 2002 (ELS) data, we estimate the influence of perceived ability under challenging conditions on advanced high school science course taking, selection of an intended STEM major, and specific major type 2 years after high school. Demonstrating the importance of specificity when discussing how gender influences STEM career pathways, the intersecting effects of gender and perceived ability under mathematics challenge were distinct for each scientific major category. Perceived ability under challenge in secondary school varied by gender, and was highly predictive of selecting PEMC and health sciences majors. Notably, women's 12th grade perceptions of their ability under mathematics challenge increased their probability of selecting PEMC majors over and above biology. In addition, gender moderated the effect of growth mindset on students' selection of health science majors. Perceptions of ability under challenge in general and verbal domains also influenced retention in and declaration of certain STEM majors. The implications of these results are discussed, with particular attention to access to advanced scientific coursework in high school and interventions aimed at enhancing young women

  19. Degree of Suppression of Mouse Myoblast Cell Line C₂C12 Differentiation Varies According to Chondroitin Sulfate Subtype.

    Science.gov (United States)

    Warita, Katsuhiko; Oshima, Nana; Takeda-Okuda, Naoko; Tamura, Jun-Ichi; Hosaka, Yoshinao Z

    2016-10-21

    Chondroitin sulfate (CS), a type of glycosaminoglycan (GAG), is a factor involved in the suppression of myogenic differentiation. CS comprises two repeating sugars and has different subtypes depending on the position and number of bonded sulfate groups. However, the effect of each subtype on myogenic differentiation remains unclear. In this study, we spiked cultures of C₂C 12 myoblasts, cells which are capable of undergoing skeletal muscle differentiation, with one of five types of CS (CS-A, -B, -C, -D, or -E) and induced differentiation over a fixed time. After immunostaining of the formed myotubes with an anti-MHC antibody, we counted the number of nuclei in the myotubes and then calculated the fusion index (FI) as a measure of myotube differentiation. The FI values of all the CS-treated groups were lower than the FI value of the control group, especially the group treated with CS-E, which displayed notable suppression of myotube formation. To confirm that the sugar chain in CS-E is important in the suppression of differentiation, chondroitinase ABC (ChABC), which catabolizes CS, was added to the media. The addition of ChABC led to the degradation of CS-E, and neutralized the suppression of myotube formation by CS-E. Collectively, it can be concluded that the degree of suppression of differentiation depends on the subtype of CS and that CS-E strongly suppresses myogenic differentiation. We conclude that the CS sugar chain has inhibitory action against myoblast cell fusion.

  20. Time-varying spectral analysis revealing differential effects of sevoflurane anaesthesia: non-rhythmic-to-rhythmic ratio.

    Science.gov (United States)

    Lin, Y-T; Wu, H-T; Tsao, J; Yien, H-W; Hseu, S-S

    2014-02-01

    Heart rate variability (HRV) may reflect various physiological dynamics. In particular, variation of R-R peak interval (RRI) of electrocardiography appears regularly oscillatory in deeper levels of anaesthesia and less regular in lighter levels of anaesthesia. We proposed a new index, non-rhythmic-to-rhythmic ratio (NRR), to quantify this feature and investigated its potential to estimate depth of anaesthesia. Thirty-one female patients were enrolled in this prospective study. The oscillatory pattern transition of RRI was visualised by the time-varying power spectrum and quantified by NRR. The prediction of anaesthetic events, including skin incision, first reaction of motor movement during emergence period, loss of consciousness (LOC) and return of consciousness (ROC) by NRR were evaluated by serial prediction probability (PK ) analysis; the ability to predict the decrease of effect-site sevoflurane concentration was also evaluated. The results were compared with Bispectral Index (BIS). NRR well-predicted first reaction (PK  > 0.90) 30 s ahead, earlier than BIS and significantly better than HRV indices. NRR well-correlated with sevoflurane concentration, although its correlation was inferior to BIS, while HRV indices had no such correlation. BIS indicated LOC and ROC best. Our findings suggest that NRR provides complementary information to BIS regarding the differential effects of anaesthetics on the brain, especially the subcortical motor activity. © 2014 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  1. Time-varying BRDFs.

    Science.gov (United States)

    Sun, Bo; Sunkavalli, Kalyan; Ramamoorthi, Ravi; Belhumeur, Peter N; Nayar, Shree K

    2007-01-01

    The properties of virtually all real-world materials change with time, causing their bidirectional reflectance distribution functions (BRDFs) to be time varying. However, none of the existing BRDF models and databases take time variation into consideration; they represent the appearance of a material at a single time instance. In this paper, we address the acquisition, analysis, modeling, and rendering of a wide range of time-varying BRDFs (TVBRDFs). We have developed an acquisition system that is capable of sampling a material's BRDF at multiple time instances, with each time sample acquired within 36 sec. We have used this acquisition system to measure the BRDFs of a wide range of time-varying phenomena, which include the drying of various types of paints (watercolor, spray, and oil), the drying of wet rough surfaces (cement, plaster, and fabrics), the accumulation of dusts (household and joint compound) on surfaces, and the melting of materials (chocolate). Analytic BRDF functions are fit to these measurements and the model parameters' variations with time are analyzed. Each category exhibits interesting and sometimes nonintuitive parameter trends. These parameter trends are then used to develop analytic TVBRDF models. The analytic TVBRDF models enable us to apply effects such as paint drying and dust accumulation to arbitrary surfaces and novel materials.

  2. Risks of fracture of Björk-Shiley 60 degree convexo-concave prosthetic heart valves: long-term cohort follow up in the UK, Netherlands and USA.

    Science.gov (United States)

    Blot, W J; Omar, R Z; Kallewaard, M; Morton, L S; Fryzek, J P; Ibrahim, M A; Acheson, D; Taylor, K M; van der Graaf, Y

    2001-03-01

    Approximately 82,000 Björk-Shiley convexo-concave (BSCC) 60 degree prosthetic heart valves were implanted in patients worldwide between 1979 and 1986. Outlet strut fractures (OSF) of some of the valves were first reported shortly after their introduction. Here, the determinants of OSF are examined, and the between-country variation and long-term risk are assessed. Cohorts of patients in the UK, Netherlands and USA with 15,770 BSCC 60 degree heart valves were followed up to 18 years for the occurrence of OSF. Crude rates of OSF were highest in the UK (0.18% per year), intermediate in the Netherlands (0.13%), and lowest in the USA (0.06%), although risk factor adjustment reduced the inter-country differences. Furthermore, in the UK and Netherlands, OSF rates (particularly for mitral valves) declined with time since implantation, and between-country differences were considerably diminished 10 or more years post implantation. The risk of OSF decreased steadily with advancing patient age. Fracture rates were lower among women than men, and also varied significantly with valve size and position and OSF status of other valves in the same shoporder. This long-term follow up of BSCC 60 degree heart valve patients indicates that risk factors for valve fracture are generally similar in the UK, Netherlands and USA. It also identifies a strong association between fracture risk and age, newly reveals gender-related differences, and shows that the risk of valve fracture persisted, albeit at a reduced rate, into the 1990s.

  3. Unbiasedness and time varying risk premia in the crude oil futures market

    International Nuclear Information System (INIS)

    Moosa, I.A.; Al-Loughani, N.E.

    1994-01-01

    This paper presents some empirical evidence on market efficiency and unbiasedness in the crude oil futures market and some related issues. On the basis of monthly observations on spot and futures prices of the West Texas Intermediate (WTI) crude oil, several tests are carried out on the relevant hypotheses. The evidence suggests that futures prices are neither unbiased nor efficient forecasters of spot prices. Furthermore, a GARCH-M(1,1) model reveals the existence of a time varying risk premium. (author)

  4. Hawk eyes I: diurnal raptors differ in visual fields and degree of eye movement.

    Directory of Open Access Journals (Sweden)

    Colleen T O'Rourke

    Full Text Available BACKGROUND: Different strategies to search and detect prey may place specific demands on sensory modalities. We studied visual field configuration, degree of eye movement, and orbit orientation in three diurnal raptors belonging to the Accipitridae and Falconidae families. METHODOLOGY/PRINCIPAL FINDINGS: We used an ophthalmoscopic reflex technique and an integrated 3D digitizer system. We found inter-specific variation in visual field configuration and degree of eye movement, but not in orbit orientation. Red-tailed Hawks have relatively small binocular areas (∼33° and wide blind areas (∼82°, but intermediate degree of eye movement (∼5°, which underscores the importance of lateral vision rather than binocular vision to scan for distant prey in open areas. Cooper's Hawks' have relatively wide binocular fields (∼36°, small blind areas (∼60°, and high degree of eye movement (∼8°, which may increase visual coverage and enhance prey detection in closed habitats. Additionally, we found that Cooper's Hawks can visually inspect the items held in the tip of the bill, which may facilitate food handling. American Kestrels have intermediate-sized binocular and lateral areas that may be used in prey detection at different distances through stereopsis and motion parallax; whereas the low degree eye movement (∼1° may help stabilize the image when hovering above prey before an attack. CONCLUSIONS: We conclude that: (a there are between-species differences in visual field configuration in these diurnal raptors; (b these differences are consistent with prey searching strategies and degree of visual obstruction in the environment (e.g., open and closed habitats; (c variations in the degree of eye movement between species appear associated with foraging strategies; and (d the size of the binocular and blind areas in hawks can vary substantially due to eye movements. Inter-specific variation in visual fields and eye movements can influence

  5. Hawk eyes I: diurnal raptors differ in visual fields and degree of eye movement.

    Science.gov (United States)

    O'Rourke, Colleen T; Hall, Margaret I; Pitlik, Todd; Fernández-Juricic, Esteban

    2010-09-22

    Different strategies to search and detect prey may place specific demands on sensory modalities. We studied visual field configuration, degree of eye movement, and orbit orientation in three diurnal raptors belonging to the Accipitridae and Falconidae families. We used an ophthalmoscopic reflex technique and an integrated 3D digitizer system. We found inter-specific variation in visual field configuration and degree of eye movement, but not in orbit orientation. Red-tailed Hawks have relatively small binocular areas (∼33°) and wide blind areas (∼82°), but intermediate degree of eye movement (∼5°), which underscores the importance of lateral vision rather than binocular vision to scan for distant prey in open areas. Cooper's Hawks' have relatively wide binocular fields (∼36°), small blind areas (∼60°), and high degree of eye movement (∼8°), which may increase visual coverage and enhance prey detection in closed habitats. Additionally, we found that Cooper's Hawks can visually inspect the items held in the tip of the bill, which may facilitate food handling. American Kestrels have intermediate-sized binocular and lateral areas that may be used in prey detection at different distances through stereopsis and motion parallax; whereas the low degree eye movement (∼1°) may help stabilize the image when hovering above prey before an attack. We conclude that: (a) there are between-species differences in visual field configuration in these diurnal raptors; (b) these differences are consistent with prey searching strategies and degree of visual obstruction in the environment (e.g., open and closed habitats); (c) variations in the degree of eye movement between species appear associated with foraging strategies; and (d) the size of the binocular and blind areas in hawks can vary substantially due to eye movements. Inter-specific variation in visual fields and eye movements can influence behavioral strategies to visually search for and track prey while

  6. A novel method for the determination of the degree of deacetylation of chitosan by coulometric titration.

    Science.gov (United States)

    Wang, Chao; Yuan, Fang; Pan, Jiabao; Jiao, Shining; Jin, Ling; Cai, Hongwei

    2014-09-01

    A novel method to determine the degree of deacetylation of chitosan is described. In this method, the coulometric titrant OH- is generated by the electrolysis of water. The OH- reacted with the residual hydrochloric acid in chitosan solution and the degree of deacetylation was obtained by Faraday's law. The optimized experimental parameters in this study were 1.0 mol/L KCl as supporting electrolyte, 15.00 mA as the intensity of constant current, composite glass electrode as indicating electrode couples, double platinum generated electrode-platinum wire auxiliary electrode as working electrode pairs, pH 3.80 as the titration end-point. The degree of deacetylation in the four samples, which varied from 70 to 95% were measured. The results were similar to those from 1H NMR and the standard deviations were lower than 0.5%. With merit of simplicity, convenience, quickness, high accuracy and precision, automatic detection of titration end-point and low-cost, the proposed method will be very useful in the industrial production. Copyright © 2014 Elsevier B.V. All rights reserved.

  7. Outcomes of torsional microcoaxial phacoemulsification performed by 12-degree and 22-degree bent tips.

    Science.gov (United States)

    Helvacioglu, Firat; Yeter, Celal; Tunc, Zeki; Sencan, Sadik

    2013-08-01

    To compare the safety and efficacy of Ozil Intelligent Phaco torsional microcoaxial phacoemulsification surgeries performed with 12-degree and 22-degree bent tips using the Infiniti Vision System. Maltepe University School of Medicine Department of Ophthalmology, Istanbul, Turkey. Comparative case series. Eyes were assigned to 2.2 mm microcoaxial phacoemulsification using the torsional mode with a 22-degree bent tip (Group 1) or a 12-degree bent tip (Group 2). The primary outcome measures were ultrasound time (UST), cumulative dissipated energy (CDE), longitudinal and torsional ultrasound (US) amplitudes, mean surgical time, mean volume of balanced salt solution used, and surgical complications. Both groups included 45 eyes. The mean UST, CDE, longitudinal US amplitude, and torsional US amplitude were 65 seconds ± 27.23 (SD), 11.53 ± 6.99, 0.22 ± 0.26, and 42.86 ± 15.64, respectively, in Group 1 and 84 ± 45.04 seconds, 16.68 ± 10.66, 0.48 ± 0.68, and 46.27 ± 14.74, respectively, in Group 2. The mean UST, CDE, and longitudinal amplitudes were significantly lower in Group 1 (P=.003, P=.008, and P=.022, respectively). The mean volume of balanced salt solution was 73.33 ± 28.58 cc in Group 1 and 82.08 ± 26.21 cc in Group 2 (P=.134). Torsional phacoemulsification performed with 22-degree bent tips provided more effective lens removal than 12-degree bent tips, with a lower UST and CDE. Copyright © 2013 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  8. Estimation of degree of sea ice ridging based on dual-polarized C-band SAR data

    Science.gov (United States)

    Gegiuc, Alexandru; Similä, Markku; Karvonen, Juha; Lensu, Mikko; Mäkynen, Marko; Vainio, Jouni

    2018-01-01

    For ship navigation in the Baltic Sea ice, parameters such as ice edge, ice concentration, ice thickness and degree of ridging are usually reported daily in manually prepared ice charts. These charts provide icebreakers with essential information for route optimization and fuel calculations. However, manual ice charting requires long analysis times, and detailed analysis of large areas (e.g. Arctic Ocean) is not feasible. Here, we propose a method for automatic estimation of the degree of ice ridging in the Baltic Sea region, based on RADARSAT-2 C-band dual-polarized (HH/HV channels) SAR texture features and sea ice concentration information extracted from Finnish ice charts. The SAR images were first segmented and then several texture features were extracted for each segment. Using the random forest method, we classified them into four classes of ridging intensity and compared them to the reference data extracted from the digitized ice charts. The overall agreement between the ice-chart-based degree of ice ridging and the automated results varied monthly, being 83, 63 and 81 % in January, February and March 2013, respectively. The correspondence between the degree of ice ridging reported in the ice charts and the actual ridge density was validated with data collected during a field campaign in March 2011. In principle the method can be applied to the seasonal sea ice regime in the Arctic Ocean.

  9. Long-term Stability of Esomeprazole in 5% Dextrose Infusion Polyolefin Bags at 5 degrees C +/- 3 degrees C after Microwave Freeze-thaw Treatment.

    Science.gov (United States)

    Hecq, Jean-daniel; Rolin, Catherine; Godet, Marie; Gillet, Patricia; Jamart, Jacques; Galanti, Laurence M

    2015-01-01

    To improve quality assurance, security, time management, and cost saving of drug delivery, preparation in advance of intravenous solutions has been developed for several infusion solutions. The objective of this study was to investigate the stability of esomeprazole 0.4 mg/mL and 0.8 mg/mL in 5% dextrose polyolefin bags after freezing, long-term storage, and microwave thawing. The stability of five polyolefin bags containing approximately 0.4 mg/mL of esomeprazole and five other bags containing approximately 0.8 mg/mL in 5% dextrose prepared under aseptic conditions was studied after freezing for 1 month at -20 degrees C, thawing in a microwave oven with a validated cycle, and stored at 5 degrees C +/- 3 degrees C. Esomeprazole concentration was measured by high-pressure liquid chromatography using a reversed-phase column C8, a mobile phase consisting of 35% of acetonitrile and 65% of Na2HPO4 buffer at pH 7.59 with HPO4 (2 M) and NaOH (0.5 M), and detection with a diode array detector at 280 nm. Visual, microscopic, and spectrophotometric observation and pH measurements were also performed. No precipitation occurred in the preparations but little change of color was observed. No microaggregate was observed with optical microscopy or revealed by a change of absorbance at 350, 410, and 550 nm. Based on a shelf life of 90% residual potency, esomeprazole solutions (0.4 and 0.8 mg/mL) were stable for at least 20 or 29 days, respectively, after a freezing and microwave thawing period, where 95% one-side lower confidence limit of the concentration-time profile remained superior to 90% of the initial concentration. During this period, the pH values of drug solutions have been observed to decrease without affecting chromatographic parameters. Within these limits, esomeprazole (0.4 and 0.8 mg/mL) in 5% dextrose infusions may be prepared and frozen in advance by a centralized intravenous admixture service, thawed, and stored at least 20 days at 5 degrees C +/- 3 degrees C

  10. Periodic solution for state-dependent impulsive shunting inhibitory CNNs with time-varying delays.

    Science.gov (United States)

    Şaylı, Mustafa; Yılmaz, Enes

    2015-08-01

    In this paper, we consider existence and global exponential stability of periodic solution for state-dependent impulsive shunting inhibitory cellular neural networks with time-varying delays. By means of B-equivalence method, we reduce these state-dependent impulsive neural networks system to an equivalent fix time impulsive neural networks system. Further, by using Mawhin's continuation theorem of coincide degree theory and employing a suitable Lyapunov function some new sufficient conditions for existence and global exponential stability of periodic solution are obtained. Previous results are improved and extended. Finally, we give an illustrative example with numerical simulations to demonstrate the effectiveness of our theoretical results. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. 45 CFR 2400.41 - Degree programs.

    Science.gov (United States)

    2010-10-01

    ... degree in history or political science (including government or politics), the degree of Master of Arts in Teaching in history or political science (including government or politics), or a related master's degree in education that permits a concentration in American history, American government, social studies...

  12. An Evaluation of Quantitative Methods of Determining the Degree of Melting Experienced by a Chondrule

    Science.gov (United States)

    Nettles, J. W.; Lofgren, G. E.; Carlson, W. D.; McSween, H. Y., Jr.

    2004-01-01

    Many workers have considered the degree to which partial melting occurred in chondrules they have studied, and this has led to attempts to find reliable methods of determining the degree of melting. At least two quantitative methods have been used in the literature: a convolution index (CVI), which is a ratio of the perimeter of the chondrule as seen in thin section divided by the perimeter of a circle with the same area as the chondrule, and nominal grain size (NGS), which is the inverse square root of the number density of olivines and pyroxenes in a chondrule (again, as seen in thin section). We have evaluated both nominal grain size and convolution index as melting indicators. Nominal grain size was measured on the results of a set of dynamic crystallization experiments previously described, where aliquots of LEW97008(L3.4) were heated to peak temperatures of 1250, 1350, 1370, and 1450 C, representing varying degrees of partial melting of the starting material. Nominal grain size numbers should correlate with peak temperature (and therefore degree of partial melting) if it is a good melting indicator. The convolution index is not directly testable with these experiments because the experiments do not actually create chondrules (and therefore they have no outline on which to measure a CVI). Thus we had no means to directly test how well the CVI predicted different degrees of melting. Therefore, we discuss the use of the CVI measurement and support the discussion with X-ray Computed Tomography (CT) data.

  13. Hybrid Strategies for Link Adaptation Exploiting Several Degrees of Freedom in OFDM Based Broadband Wireless Systems

    DEFF Research Database (Denmark)

    Das, Suvra S.; Rahman, Muhammad Imadur; Wang, Yuanye

    2007-01-01

    In orthogonal frequency division multiplexing (OFDM) systems, there are several degrees of freedom in time and frequency domain, such as, sub-band size, forward error control coding (FEC) rate, modulation order, power level, modulation adaptation interval, coding rate adaptation interval and powe...... of the link parameters based on the channel conditions would lead to highly complex systems with high overhead. Hybrid strategies to vary the adaptation rates to tradeoff achievable efficiency and complexity are presented in this work....

  14. Grass-specific CD4+ T-cells exhibit varying degrees of cross-reactivity, implications for allergen-specific immunotherapy

    Science.gov (United States)

    Archila, LD; DeLong, JH; Wambre, E; James, EA; Robinson, DM; Kwok, WW

    2014-01-01

    Background Conceptually, allergic responses may involve cross-reactivity by antibodies or T-cells. While IgE cross-reactivity amongst grass pollen allergens has been observed, cross-reactivity at the allergen-specific T-cell level has been less documented. Identification of the patterns of cross-reactivity may improve our understanding, allowing optimization of better immunotherapy strategies. Objectives We use Phleum pratense as model for the studying of cross-reactivity at the allergen-specific CD4+ T cell level amongst DR04:01 restricted Pooideae grass pollen T-cell epitopes. Methods After In vitro culture of blood mononucleated cells from Grass-pollen allergic subjects with specific Pooideae antigenic epitopes, dual tetramer staining with APC-labeled DR04:01/Phleum pratense tetramers and PE-labeled DR04:01/Pooideae grass homolog tetramers was assessed to identify cross-reactivity amongst allergen-specific DR04:01-restricted T-cells in 6 subjects. Direct ex vivo staining enabled the comparison of frequency and phenotype of different Pooideae grass pollen reactive T-cells. Intracellular cytokine staining (ICS) assays were also used to examine phenotypes of these T-cells. Results T-cells with various degree of cross reactive profiles could be detected. Poa p 1 97-116, Lol p 1 221-240, Lol p 5a 199-218, and Poa p 5a 199-218 were identified as minimally-cross-reactive T-cell epitopes that do not show cross reactivity to Phl p 1 and Phl p 5a epitopes. Ex vivo tetramer staining assays demonstrated T-cells that recognized these minimally-cross reactive T-cell epitopes are present in Grass-pollen allergic subjects. Conclusions Our results suggest that not all Pooideae grass epitopes with sequence homology are cross-reactive. Non-cross reactive T-cells with comparable frequency, phenotype and functionality to Phl p-specific T-cells, suggest that a multiple allergen system should be considered for immunotherapy instead of a mono allergen system. PMID:24708411

  15. Grass-specific CD4(+) T-cells exhibit varying degrees of cross-reactivity, implications for allergen-specific immunotherapy.

    Science.gov (United States)

    Archila, L D; DeLong, J H; Wambre, E; James, E A; Robinson, D M; Kwok, W W

    2014-07-01

    Conceptually, allergic responses may involve cross-reactivity by antibodies or T-cells. While IgE cross-reactivity among grass-pollen allergens has been observed, cross-reactivity at the allergen-specific T-cell level has been less documented. Identification of the patterns of cross-reactivity may improve our understanding, allowing optimization of better immunotherapy strategies. We use Phleum pratense as model for the studying of cross-reactivity at the allergen-specific CD4(+) T cell level among DR04:01 restricted Pooideae grass-pollen T-cell epitopes. After in vitro culture of blood mono-nucleated cells from grass-pollen-allergic subjects with specific Pooideae antigenic epitopes, dual tetramer staining with APC-labelled DR04:01/Phleum pratense tetramers and PE-labelled DR04:01/Pooideae grass homolog tetramers was assessed to identify cross-reactivity among allergen-specific DR04:01-restricted T-cells in six subjects. Direct ex vivo staining enabled the comparison of frequency and phenotype of different Pooideae grass-pollen reactive T-cells. Intracellular cytokine staining (ICS) assays were also used to examine phenotypes of these T-cells. T-cells with various degrees of cross-reactive profiles could be detected. Poa p 1 97-116 , Lol p 1 221-240 , Lol p 5a 199-218 , and Poa p 5a 199-218 were identified as minimally cross-reactive T-cell epitopes that do not show cross-reactivity to Phl p 1 and Phl p 5a epitopes. Ex vivo tetramer staining assays demonstrated T-cells that recognized these minimally cross-reactive T-cell epitopes are present in Grass-pollen-allergic subjects. Our results suggest that not all Pooideae grass epitopes with sequence homology are cross-reactive. Non-cross-reactive T-cells with comparable frequency, phenotype and functionality to Phl p-specific T-cells suggest that a multiple allergen system should be considered for immunotherapy instead of a mono-allergen system. © 2014 John Wiley & Sons Ltd.

  16. Virtual displays for 360-degree video

    Science.gov (United States)

    Gilbert, Stephen; Boonsuk, Wutthigrai; Kelly, Jonathan W.

    2012-03-01

    In this paper we describe a novel approach for comparing users' spatial cognition when using different depictions of 360- degree video on a traditional 2D display. By using virtual cameras within a game engine and texture mapping of these camera feeds to an arbitrary shape, we were able to offer users a 360-degree interface composed of four 90-degree views, two 180-degree views, or one 360-degree view of the same interactive environment. An example experiment is described using these interfaces. This technique for creating alternative displays of wide-angle video facilitates the exploration of how compressed or fish-eye distortions affect spatial perception of the environment and can benefit the creation of interfaces for surveillance and remote system teleoperation.

  17. Measuring Direct Teaching Costs: Does an Undergraduate Business Degree Cost More to Produce than a Nonbusiness Degree?

    Science.gov (United States)

    Barth, Michael M.; Karagiannidis, Iordanis

    2016-01-01

    Many universities have implemented tuition differentials for certain undergraduate degree programs, citing higher degree costs or higher demand. However, most college accounting systems are unsuited for measuring cost differentials by degree program. This research outlines a method that can convert commonly available financial data to a more…

  18. Inflation and late-time acceleration in braneworld cosmological models with varying brane tension

    International Nuclear Information System (INIS)

    Wong, K.C.; Cheng, K.S.; Harko, T.

    2010-01-01

    Braneworld models with variable brane tension λ introduce a new degree of freedom that allows for evolving gravitational and cosmological constants, the latter being a natural candidate for dark energy. We consider a thermodynamic interpretation of the varying brane tension models, by showing that the field equations with variable λ can be interpreted as describing matter creation in a cosmological framework. The particle creation rate is determined by the variation rate of the brane tension, as well as by the brane-bulk energy-matter transfer rate. We investigate the effect of a variable brane tension on the cosmological evolution of the Universe, in the framework of a particular model in which the brane tension is an exponentially dependent function of the scale factor. The resulting cosmology shows the presence of an initial inflationary expansion, followed by a decelerating phase, and by a smooth transition towards a late accelerated de Sitter type expansion. The varying brane tension is also responsible for the generation of the matter in the Universe (reheating period). The physical constraints on the model parameters, resulting from the observational cosmological data, are also investigated. (orig.)

  19. Labeling schemes for bounded degree graphs

    DEFF Research Database (Denmark)

    Adjiashvili, David; Rotbart, Noy Galil

    2014-01-01

    We investigate adjacency labeling schemes for graphs of bounded degree Δ = O(1). In particular, we present an optimal (up to an additive constant) log n + O(1) adjacency labeling scheme for bounded degree trees. The latter scheme is derived from a labeling scheme for bounded degree outerplanar...... graphs. Our results complement a similar bound recently obtained for bounded depth trees [Fraigniaud and Korman, SODA 2010], and may provide new insights for closing the long standing gap for adjacency in trees [Alstrup and Rauhe, FOCS 2002]. We also provide improved labeling schemes for bounded degree...

  20. Pollinator-mediated interactions in experimental arrays vary with neighbor identity.

    Science.gov (United States)

    Ha, Melissa K; Ivey, Christopher T

    2017-02-01

    Local ecological conditions influence the impact of species interactions on evolution and community structure. We investigated whether pollinator-mediated interactions between coflowering plants vary with plant density, coflowering neighbor identity, and flowering season. We conducted a field experiment in which flowering time and floral neighborhood were manipulated in a factorial design. Early- and late-flowering Clarkia unguiculata plants were placed into arrays with C. biloba neighbors, noncongeneric neighbors, additional conspecific plants, or no additional plants as a density control. We compared whole-plant pollen limitation of seed set, pollinator behavior, and pollen deposition among treatments. Interactions mediated by shared pollinators depended on the identity of the neighbor and possibly changed through time, although flowering-season comparisons were compromised by low early-season plant survival. Interactions with conspecific neighbors were likely competitive late in the season. Interactions with C. biloba appeared to involve facilitation or neutral interactions. Interactions with noncongeners were more consistently competitive. The community composition of pollinators varied among treatment combinations. Pollinator-mediated interactions involved competition and likely facilitation, depending on coflowering neighbor. Experimental manipulation helped to reveal context-dependent variation in indirect biotic interactions. © 2017 Botanical Society of America.

  1. SEM-EDS and XRD study of a NiCrAlU alloy at temperatures from 800 celsius degree to 1300 celsius degree

    International Nuclear Information System (INIS)

    Al-Badairy, H.; Fox, P.

    2004-01-01

    Full text.The oxidation behaviour of a 74.5wt%Ni, 20wt%Cr, 5wt%Al and 0.5wt%U alloy was examined using Scanning Electron Microscopy with X-ray Energy Dispersive Spectroscopy (SEM-EDS) and X-ray Diffractometry (XRD). The oxidation temperature ranged from 800 to 1300 celsius degree in laboratory air with oxidation times up to 120h. Analysis showed that during short term oxidation (40h) at the lower temperatures there was evidence of the formation of Cr, Ni and Al oxides. With increasing oxidation time, the Cr-rich oxide became predominant with the presence of islands of Ni-rich oxide, but no uranium was detected at the outermost layer of the scale. The scale was of flat topography with spallation occurring after 40h oxidation at 900 celsius degree and increasing with increasing temperature and time. Cross-sectional investigations indicated the presence of an internal oxidation zone comprising an Al-rich oxide beneath the outer Cr-rich scale with significant amounts of uranium. The depth of this zone varied from 1 micron to 60 microns and increased with increasing the oxidation temperature and time. At higher temperatures (above 1000 celsius degree), the internal oxidation zone ceased to grow due to the formation of a complete layer of alumina which protected the metal substrate from further degradation. The constituents of the scales formed reflect the selective oxidation of Cr and Al as a result of the higher reactivity of aluminium and chromium compared to nickel and the greater stability of Al 2 O 3 and Cr 2 O 3 compared to NiO. This study showed that Al-rich oxide was not the predominant protective oxide and the presence of uranium was restricted to the grain boundaries of the metal substrate and to within the internal oxidation zone. It appeared that the Cr-rich scale formed on this alloy does not to convolute. This may be due to the influence of uranium since Cr-rich scales forming on NiCrAl containing no uranium are often convoluted

  2. A varying-α brane world cosmology

    International Nuclear Information System (INIS)

    Youm, Donam

    2001-08-01

    We study the brane world cosmology in the RS2 model where the electric charge varies with time in the manner described by the varying fine-structure constant theory of Bekenstein. We map such varying electric charge cosmology to the dual variable-speed-of-light cosmology by changing system of units. We comment on cosmological implications for such cosmological models. (author)

  3. Lessons Learned: Creating an Online Business Degree from a Successful On-Campus Business Degree

    Science.gov (United States)

    Cordeiro, William P.; Muraoka, Dennis

    2015-01-01

    The horse has left the barn. Distance education is here to stay and the number of degree programs offered online is growing rapidly. California State University Channel Islands (CI) admitted its first students in 2002, and the undergraduate and graduate degrees in business were among its first program offerings. From its inception, the…

  4. Cooling hyperthermic firefighters by immersing forearms and hands in 10 degrees C and 20 degrees C water.

    Science.gov (United States)

    Giesbrecht, Gordon G; Jamieson, Christopher; Cahill, Farrell

    2007-06-01

    Firefighters experience significant heat stress while working with heavy gear in a hot, humid environment. This study compared the cooling effectiveness of immersing the forearms and hands in 10 and 20 degrees C water. Six men (33 +/- 10 yr; 180 +/- 4 cm; 78 +/- 9 kg; 19 +/- 5% body fat) wore firefighter 'turn-out gear' (heavy clothing and breathing apparatus weighing 27 kg) in a protocol including three 20-min exercise bouts (step test, 78 W, 40 degrees C air, 40% RH) each followed by a 20-min rest/cooling (21 degrees C air); i.e., 60 min of exercise, 60 min of cooling. Turn-out gear was removed during rest/cooling periods and subjects either rested (Control), immersed their hands in 10 or 20 degrees C water (H-10, H-20), or immersed their hands and forearms in 10 or 20 degrees C water (HF-10, HF-20). In 20 degrees C water, hand immersion did not reduce core temperature compared with Control; however, including forearm immersion decreased core temperature below Control values after both the second and final exercise periods (p hand immersion produced a lower core temperature (0.8 degrees C above baseline) than all other conditions (1.1 to 1.4 degrees C above baseline) after the final exercise period (p Hand and forearm immersion in cool water is simple, reduces heat strain, and may increase work performance in a hot, humid environment. With 20 degrees C water, forearms should be immersed with the hands to be effective. At lower water temperatures, forearm and/or hand immersion will be effective, although forearm immersion will decrease core temperature further.

  5. Hydrodynamic mean-field solutions of 1D exclusion processes with spatially varying hopping rates

    Energy Technology Data Exchange (ETDEWEB)

    Lakatos, Greg; O' Brien, John; Chou, Tom [Department of Biomathematics and Institute for Pure and Applied Mathematics, UCLA, Los Angeles, CA 90095 (United States)

    2006-03-10

    We analyse the open boundary partially asymmetric exclusion process with smoothly varying internal hopping rates in the infinite-size, mean-field limit. The mean-field equations for particle densities are written in terms of Ricatti equations with the steady-state current J as a parameter. These equations are solved both analytically and numerically. Upon imposing the boundary conditions set by the injection and extraction rates, the currents J are found self-consistently. We find a number of cases where analytic solutions can be found exactly or approximated. Results for J from asymptotic analyses for slowly varying hopping rates agree extremely well with those from extensive Monte Carlo simulations, suggesting that mean-field currents asymptotically approach the exact currents in the hydrodynamic limit, as the hopping rates vary slowly over the lattice. If the forward hopping rate is greater than or less than the backward hopping rate throughout the entire chain, the three standard steady-state phases are preserved. Our analysis reveals the sensitivity of the current to the relative phase between the forward and backward hopping rate functions.

  6. Hydrodynamic mean-field solutions of 1D exclusion processes with spatially varying hopping rates

    International Nuclear Information System (INIS)

    Lakatos, Greg; O'Brien, John; Chou, Tom

    2006-01-01

    We analyse the open boundary partially asymmetric exclusion process with smoothly varying internal hopping rates in the infinite-size, mean-field limit. The mean-field equations for particle densities are written in terms of Ricatti equations with the steady-state current J as a parameter. These equations are solved both analytically and numerically. Upon imposing the boundary conditions set by the injection and extraction rates, the currents J are found self-consistently. We find a number of cases where analytic solutions can be found exactly or approximated. Results for J from asymptotic analyses for slowly varying hopping rates agree extremely well with those from extensive Monte Carlo simulations, suggesting that mean-field currents asymptotically approach the exact currents in the hydrodynamic limit, as the hopping rates vary slowly over the lattice. If the forward hopping rate is greater than or less than the backward hopping rate throughout the entire chain, the three standard steady-state phases are preserved. Our analysis reveals the sensitivity of the current to the relative phase between the forward and backward hopping rate functions

  7. Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue

    Directory of Open Access Journals (Sweden)

    Kevin M. Harlen

    2016-06-01

    Full Text Available Transcription controls splicing and other gene regulatory processes, yet mechanisms remain obscure due to our fragmented knowledge of the molecular connections between the dynamically phosphorylated RNA polymerase II (Pol II C-terminal domain (CTD and regulatory factors. By systematically isolating phosphorylation states of the CTD heptapeptide repeat (Y1S2P3T4S5P6S7, we identify hundreds of protein factors that are differentially enriched, revealing unappreciated connections between the Pol II CTD and co-transcriptional processes. These data uncover a role for threonine-4 in 3′ end processing through control of the transition between cleavage and termination. Furthermore, serine-5 phosphorylation seeds spliceosomal assembly immediately downstream of 3′ splice sites through a direct interaction with spliceosomal subcomplex U1. Strikingly, threonine-4 phosphorylation also impacts splicing by serving as a mark of co-transcriptional spliceosome release and ensuring efficient post-transcriptional splicing genome-wide. Thus, comprehensive Pol II interactomes identify the complex and functional connections between transcription machinery and other gene regulatory complexes.

  8. Tenth value layers for 60Co gamma rays and for 4, 6, 10, 15, and 18 MV x rays in concrete for beams of cone angles between 0 degrees and 14 degrees calculated by Monte Carlo simulation.

    Science.gov (United States)

    Jaradat, Adnan K; Biggs, Peter J

    2007-05-01

    The calculation of shielding barrier thicknesses for radiation therapy facilities according to the NCRP formalism is based on the use of broad beams (that is, the maximum possible field sizes). However, in practice, treatment fields used in radiation therapy are, on average, less than half the maximum size. Indeed, many contemporary treatment techniques call for reduced field sizes to reduce co-morbidity and the risk of second cancers. Therefore, published tenth value layers (TVLs) for shielding materials do not apply to these very small fields. There is, hence, a need to determine the TVLs for various beam modalities as a function of field size. The attenuation of (60)Co gamma rays and photons of 4, 6, 10, 15, and 18 MV bremsstrahlung x ray beams by concrete has been studied using the Monte Carlo technique (MCNP version 4C2) for beams of half-opening angles of 0 degrees , 3 degrees , 6 degrees , 9 degrees , 12 degrees , and 14 degrees . The distance between the x-ray source and the distal surface of the shielding wall was fixed at 600 cm, a distance that is typical for modern radiation therapy rooms. The maximum concrete thickness varied between 76.5 cm and 151.5 cm for (60)Co and 18 MV x rays, respectively. Detectors were placed at 630 cm, 700 cm, and 800 cm from the source. TVLs have been determined down to the third TVL. Energy spectra for 4, 6, 10, 15, and 18 MV x rays for 10 x 10 cm(2) and 40 x 40 cm(2) field sizes were used to generate depth dose curves in water that were compared with experimentally measured values.

  9. Removal of antibiotic-resistant bacteria and antibiotic resistance genes affected by varying degrees of fouling on anaerobic microfiltration membranes

    KAUST Repository

    Cheng, Hong; Hong, Pei-Ying

    2017-01-01

    An anaerobic membrane bioreactor was retrofitted with polyvinylidene fluoride (PVDF) microfiltration membrane units, each of which was fouled to a different extent. The membranes with different degrees of fouling were evaluated for their efficiencies in removing three antibiotic-resistant bacteria (ARB), namely, blaNDM-1-positive Escherichia coli PI-7, blaCTX-M-15-positive Klebsiella pneumoniae L7, and blaOXA-48-positive E. coli UPEC-RIY-4, as well as their associated plasmid-borne antibiotic resistance genes (ARGs). The results showed that the log removal values (LRVs) of ARGs correlated positively with the extent of membrane fouling and ranged from 1.9 to 3.9. New membranes with a minimal foulant layer could remove more than 5 log units of ARB. However, as the membranes progressed to subcritical fouling, the LRVs of ARB decreased at increasing operating transmembrane pressures (TMPs). The LRV recovered back to 5 when the membrane was critically fouled, and the achieved LRV remained stable at different operating TMPs. Furthermore, characterization of the surface attributed the removal of both the ARB and ARGs to adsorption, which was facilitated by an increasing hydrophobicity and a decreasing surface ζ potential as the membranes fouled. Our results indicate that both the TMP and the foulant layer synergistically affected ARB removal, but the foulant layer was the main factor that contributed to ARG removal.

  10. Removal of Antibiotic-Resistant Bacteria and Antibiotic Resistance Genes Affected by Varying Degrees of Fouling on Anaerobic Microfiltration Membranes.

    Science.gov (United States)

    Cheng, Hong; Hong, Pei-Ying

    2017-11-07

    An anaerobic membrane bioreactor was retrofitted with polyvinylidene fluoride (PVDF) microfiltration membrane units, each of which was fouled to a different extent. The membranes with different degrees of fouling were evaluated for their efficiencies in removing three antibiotic-resistant bacteria (ARB), namely, bla NDM-1 -positive Escherichia coli PI-7, bla CTX-M-15 -positive Klebsiella pneumoniae L7, and bla OXA-48 -positive E. coli UPEC-RIY-4, as well as their associated plasmid-borne antibiotic resistance genes (ARGs). The results showed that the log removal values (LRVs) of ARGs correlated positively with the extent of membrane fouling and ranged from 1.9 to 3.9. New membranes with a minimal foulant layer could remove more than 5 log units of ARB. However, as the membranes progressed to subcritical fouling, the LRVs of ARB decreased at increasing operating transmembrane pressures (TMPs). The LRV recovered back to 5 when the membrane was critically fouled, and the achieved LRV remained stable at different operating TMPs. Furthermore, characterization of the surface attributed the removal of both the ARB and ARGs to adsorption, which was facilitated by an increasing hydrophobicity and a decreasing surface ζ potential as the membranes fouled. Our results indicate that both the TMP and the foulant layer synergistically affected ARB removal, but the foulant layer was the main factor that contributed to ARG removal.

  11. Removal of antibiotic-resistant bacteria and antibiotic resistance genes affected by varying degrees of fouling on anaerobic microfiltration membranes

    KAUST Repository

    Cheng, Hong

    2017-09-28

    An anaerobic membrane bioreactor was retrofitted with polyvinylidene fluoride (PVDF) microfiltration membrane units, each of which was fouled to a different extent. The membranes with different degrees of fouling were evaluated for their efficiencies in removing three antibiotic-resistant bacteria (ARB), namely, blaNDM-1-positive Escherichia coli PI-7, blaCTX-M-15-positive Klebsiella pneumoniae L7, and blaOXA-48-positive E. coli UPEC-RIY-4, as well as their associated plasmid-borne antibiotic resistance genes (ARGs). The results showed that the log removal values (LRVs) of ARGs correlated positively with the extent of membrane fouling and ranged from 1.9 to 3.9. New membranes with a minimal foulant layer could remove more than 5 log units of ARB. However, as the membranes progressed to subcritical fouling, the LRVs of ARB decreased at increasing operating transmembrane pressures (TMPs). The LRV recovered back to 5 when the membrane was critically fouled, and the achieved LRV remained stable at different operating TMPs. Furthermore, characterization of the surface attributed the removal of both the ARB and ARGs to adsorption, which was facilitated by an increasing hydrophobicity and a decreasing surface ζ potential as the membranes fouled. Our results indicate that both the TMP and the foulant layer synergistically affected ARB removal, but the foulant layer was the main factor that contributed to ARG removal.

  12. KOH activation of pitch-derived carbonaceous materials - Effect of carbonization degree

    Energy Technology Data Exchange (ETDEWEB)

    Krol, Magdalena [Institute of Open Cast Mining POLTEGOR-Institute, Parkowa, Wroclaw (Poland); Gryglewicz, Grazyna; Machnikowski, Jacek [Division of Polymer and Carbonaceous Materials, Faculty of Chemistry, Wroclaw University of Technology, Gdanska (Poland)

    2011-01-15

    Two series of mesophase pitches and semi-cokes of different carbonization degree were produced by heat treatment of anthracene oil derived pitches P1 and P4 in the temperature range of 460-700 C. These carbonaceous materials were activated with potassium hydroxide at 700 C using 1:3 reagents ratio to assess the effects of the precursor optical texture and carbonization degree on the activation behavior. The results show that the increase in the pitch pretreatment temperature suppresses propensity to the pore generation while enhancing particle breaking. The effect can be illustrated by decreases in the BET surface area S{sub BET} from {proportional_to} 2700 to {proportional_to} 1500 m{sup 2} g{sup -1} and the micropore volume V{sub DR} from {proportional_to} 0.85 to {proportional_to} 0.45 cm{sup 3} g{sup -1}. These parameters are inversely related with the H/C atomic ratio of precursor. In contrast, the anisotropic development of pitch coke, varying from flow type to mosaics, has a slight effect on the activation behaviour. The mechanism of porosity generation, that is proposed, stresses the role of hydrogen occurring at the edges of graphene layers and potassium metal insertion/deinsertion on the porosity development and particle disintegration during KOH activation of pitch-derived carbons. (author)

  13. Pathways to a Four-Year Degree: Determinants of Degree Completion among Socioeconomically Disadvantaged Students.

    Science.gov (United States)

    Cabrera, Alberto F.; Burkum, Kurt R.; La Nasa, Steven M.

    The High School Sophomore Cohort of 1980 followed nine different pathways to a 4-year college degree. These paths were formed by a combination of different levels of academic preparation secured in high school and the first type of postsecondary institution attended. The pathway most likely to lead to a 4-year degree is one defined by acquiring…

  14. The language and social background questionnaire: Assessing degree of bilingualism in a diverse population.

    Science.gov (United States)

    Anderson, John A E; Mak, Lorinda; Keyvani Chahi, Aram; Bialystok, Ellen

    2018-02-01

    Research examining the cognitive consequences of bilingualism has expanded rapidly in recent years and has revealed effects on aspects of cognition across the lifespan. However, these effects are difficult to find in studies investigating young adults. One problem is that there is no standard definition of bilingualism or means of evaluating degree of bilingualism in individual participants, making it difficult to directly compare the results of different studies. Here, we describe an instrument developed to assess degree of bilingualism for young adults who live in diverse communities in which English is the official language. We demonstrate the reliability and validity of the instrument in analyses based on 408 participants. The relevant factors for describing degree of bilingualism are: (1) the extent of non-English language proficiency and use at home, and (2) non-English language use socially. We then use the bilingualism scores obtained from the instrument to demonstrate their association with: (1) performance on executive function tasks, and (2) previous classifications of participants into categories of monolinguals and bilinguals.

  15. Effect of the degree of high power impulse magnetron sputtering utilisation on the structure and properties of TiN films

    Energy Technology Data Exchange (ETDEWEB)

    Hovsepian, Papken Eh.; Sugumaran, Arunprabhu A., E-mail: Arunprabhu.ArunachalamSugumaran@student.shu.ac.uk; Purandare, Yashodhan; Loch, Daniel A.L.; Ehiasarian, Arutiun P.

    2014-07-01

    TiN films were deposited using high power impulse magnetron sputtering (HIPIMS) enabled four cathode industrial size coating system equipped with HIPIMS power supplies. The standard version of this system allows control over the ion bombardment during coating growth by varying the strength of the electromagnetic field of the unbalancing coils and bias voltage applied to the substrate. The coatings were produced in different coating growth conditions achieved in combined HIPIMS — direct current (dc) unbalanced magnetron sputtering (HIPIMS/UBM) processes where HIPIMS was used as an additional tool to manipulate the ionisation degree in the plasma. Four cathode combinations were explored with increasing contribution of HIPIMS namely 4UBM (pure UBM), 1HIPIMS + 3UBM, 2HIPIMS + 2UBM and 2HIPIMS (pure HIPIMS) to deposit TiN coatings. Optical emission spectroscopy (OES) measurements were carried out to examine the plasma generated by the various combinations of HIPIMS and UBM cathodes. The micro-structural study was done by scanning electron microscopy (SEM). X-ray diffraction (XRD) technique was used to calculate the residual stress and texture parameter. It has been revealed that the residual stress can be controlled in a wide range from − 0.22 GPa to − 11.67 GPa by intelligent selection of the degree of HIPIMS utilisation, strength of the electromagnetic field of the unbalancing coils and the bias voltage applied to the substrate while maintaining the stoichiometry of the coatings. The effect of the degree of HIPIMS utilisation on the microstructure, texture and residual stress is discussed. Combining HIPIMS with dc-UBM sputtering is also seen as an effective tool for improving the productivity of the deposition process. - Highlights: • High {Ti"1"+} in the plasma with increasing number of HIPIMS sources • Residual stress can be manipulated in a wide range. • Texture can be altered. • The 2HIPIMS + 2UBM combination appears to be the most advantageous.

  16. Revisiting diversity: cultural variation reveals the constructed nature of emotion perception.

    Science.gov (United States)

    Gendron, Maria

    2017-10-01

    The extent of cultural variation in emotion perception has long been assumed to be bounded by underlying universality. A growing body of research reveals, however, that evidence of universality in emotion perception is method-bound. Without the assumption of underlying universality, new lines of inquiry become relevant. Accumulating evidence suggests that cultures vary in what cues are relevant to perceptions of emotion. Further, cultural groups vary in their spontaneous inferences; mental state inference does not appear to be the only, or even most routine, mode of perception across cultures. Finally, setting universality assumptions aside requires innovation in the theory and measurement of culture. Recent studies reveal the promise of refinements in psychological approaches to culture. Together, the available evidence is consistent with a view of emotion perceptions as actively constructed by perceivers to fit the social and physical constraints of their cultural worlds. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. A study of the lived experiences of African American women STEM doctoral degree completers

    Science.gov (United States)

    Squires, Stephanie Michelle

    This study examined the lived experiences of African American women (AAW) who completed doctoral degrees in a STEM (science, technology, engineering, and mathematics) discipline in the United States. This study sought to fill the gap in the literature by examining how AAW described and made meaning of lived STEM educational experiences during doctoral degree completion in the context of the intersection of being African American and a woman. This study utilized a theoretical perspective based upon three theories: (a) critical race theory as a framework to gather AAW's narratives about STEM doctorate education, (b) Black feminist thought as a framework to view the intersection of being African American and a woman in the United States, and (c) the science identity model as a framework to view how women of color successfully complete scientific graduate degrees. Participants revealed that being an African American and a woman in a STEM doctoral program often complicated an already difficult process of completing the doctoral degree. The participants described the educational experience as challenging, particularly the writing of the dissertation. The challenges that the participants faced were due to various factors such as difficult advisor/advisee relationships, tedious writing and revision processes, politics, and lack of information regarding the doctoral degree process. The findings suggested that AAW participants confronted intrinsic bias while completing STEM doctoral degrees, which led to isolation and feelings of being an impostor---or feelings of not belonging in scientific studies. The findings also indicated that the women in this study ascribed success in dissertation writing and degree completion to one or more of the following attributes: (a) having a clear plan, (b) taking ownership of the writing process, (c) having an engaged advisor, (d) learning the writing style of the advisor, (e) understanding the temperament of the advisor, (f) personal will

  18. Consumer and trained panel evaluation of beef strip steaks of varying marbling and enhancement levels cooked to three degrees of doneness.

    Science.gov (United States)

    Lucherk, L W; O'Quinn, T G; Legako, J F; Rathmann, R J; Brooks, J C; Miller, M F

    2016-12-01

    The palatability of USDA graded beef strip loins of seven treatments [High Enhanced (HE: 112% of raw weight) Select, Low Enhanced (LE: 107% of raw weight) Select, Prime, upper 2/3 Choice (Top Choice), lower 1/3 Choice (Low Choice), Select, and Standard] cooked to three degrees of doneness [DOD; rare (60°C), medium (71°C), or well-done (77°C)] was evaluated by consumer and trained sensory panelists. For consumers, Select HE steaks rated higher (P0.05) were observed between Select LE and Prime samples for most traits evaluated. The effect of USDA grade and enhancement on trained panel palatability scores was independent of DOD for all traits other than juiciness, with the role of marbling in juiciness increasing as DOD increased from rare to well-done. These results indicate enhancement as an effective method to improve the palatability of lower grading beef. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Variation in chemical, colloidal and electrochemical properties of carbon nanotubes with the degree of carboxylation

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Zheqiong; Wang, Zhiqian; Yu, Fang; Thakkar, Megha; Mitra, Somenath, E-mail: mitra@njit.edu [New Jersey Institute of Technology, Department of Chemistry and Environmental Science (United States)

    2017-01-15

    Multiwalled carbon nanotubes (CNTs) were carboxylated via microwave irradiation where the treatment time was varied to alter the degree of functionalization, and as many as one in 15 carbons in the CNT could be oxidized. Chemical, physical, electrochemical, and colloidal behavior of the carboxylated CNTs was studied. All properties changed with the degree of functionalization to a point beyond which they appeared to remain constant. The surface area increased from 173.9 to 270.9 m{sup 2}/g while the critical coagulation concentration (CCC) values increased from 142.14 to 168.69 mM in the presence of NaCl, and the corresponding increase was from 0.97 to 5.32 mM in the presence of MgCl{sub 2}. As seen from cyclic voltammetry curves, the functionalized CNTs showed mainly non-Faradic interactions with Na{sub 2}SO{sub 4,} but showed Faradic behaviors in alkaline KOH.

  20. Physics to a degree

    CERN Document Server

    Thomas, EG

    2014-01-01

    Physics to a Degree provides an extensive collection of problems suitable for self-study or tutorial and group work at the level of an undergraduate physics course. This novel set of exercises draws together the core elements of an undergraduate physics degree and provides students with the problem solving skills needed for general physics' examinations and for real-life situations encountered by the professional physicist. Topics include force, momentum, gravitation, Bernoulli's Theorem, magnetic fields, blackbody radiation, relativistic travel, mechanics near the speed of light, radioactive

  1. Effect of the Degree of Polymerization of Inulin on the Rate of Hydrolysis Using Immobilized Inulinase

    Directory of Open Access Journals (Sweden)

    Emanuele Ricca

    2014-01-01

    Full Text Available The present paper addresses two crucial features in the industrial development of fructose production by enzymatic hydrolysis of inulin: the use of immobilized biocatalyst in the hydrolysis of crude extracts of chicory roots and the evaluation of the effect of degree of polymerization of inulin on the overall reaction rate. The immobilized biocatalyst consisted of inulinase covalently bound to Sepabeads® supports. It was demonstrated that its catalytic activity towards crude inulin extract (real substrate was much higher than that exhibited towards pure inulin (synthetic solution. Experiments revealed that, in applications of practical interest with real substrate, the activity of immobilized enzyme was as high as 63 % of that of free enzyme in homogeneous solution. This certainly was a driving force to potential industrial application of this immobilized enzyme preparation. Therefore, the effect of pure and crude substrates on the kinetics of the reaction catalysed by the immobilized enzyme was investigated. The kinetic analysis revealed a Michaelis-Menten dependence of the reaction rate on substrate concentration for both pure (high molecular mass and crude (low molecular mass inulin. Interesting results were derived from the comparison of Km and vmax values in the two cases. In particular, it was found that increasing degree of polymerization of the substrate caused vmax decrease and Km increase. After evaluation of mass transport effects, this was mainly associated with a different substrate/ enzyme affinity when exploiting inulin characterized by different (low or high degree of polymerization.

  2. Nonextensive dust acoustic waves in a charge varying dusty plasma

    Science.gov (United States)

    Bacha, Mustapha; Tribeche, Mouloud

    2012-01-01

    Our recent analysis on nonlinear nonextensive dust-acoustic waves (DA) [Amour and Tribeche in Phys. Plasmas 17:063702, 2010] is extended to include self-consistent nonadiabatic grain charge fluctuation. The appropriate nonextensive electron charging current is rederived based on the orbit-limited motion theory. Our results reveal that the amplitude, strength and nature of the nonlinear DA waves (solitons and shocks) are extremely sensitive to the degree of ion nonextensivity. Stronger is the electron correlation, more important is the charge variation induced nonlinear wave damping. The anomalous dissipation effects may prevail over that dispersion as the electrons evolve far away from their Maxwellian equilibrium. Our investigation may be of wide relevance to astronomers and space scientists working on interstellar dusty plasmas where nonthermal distributions are turning out to be a very common and characteristic feature.

  3. Does a bachelor’s degree pay off?

    DEFF Research Database (Denmark)

    Neugebauer, Martin; Weiss, Felix

    Academic education is generally rewarded by employers, but what happens to graduates if they are trained for two years less and have to compete with vocationally trained labor market entrants in a similar field of study? Focusing on Germany, we analyze labor market entries of individuals eligible...... for higher education, who either opted for newly introduced short bachelor’s degrees, or for well-established vocational degrees. Based on Microcensus data, we find that bachelor’s degrees from classical universities are associated with higher earnings and more prestigious jobs than initial vocational...... training degrees, and with higher prestige (but similar earnings) than further vocational degrees. However, bachelor’s degrees from universities are also related to higher risks of unemployment or fixed-term employment. Universities of applied sciences, which combine academic and practical training, offer...

  4. Therapeutic Benefits of Tocilizumab Vary in Different Organs of a Patient with AA Amyloidosis

    Directory of Open Access Journals (Sweden)

    Masaru Matsui

    2014-01-01

    Full Text Available Systemic reactive AA amyloidosis is a life-threatening complication of chronic inflammatory diseases. Anti-interleukin-6 receptor, tocilizumab (TCZ, has been shown to improve clinical symptoms of patients with AA amyloidosis, accompanied with regression of the amyloid deposition. We report a case of AA amyloidosis evaluated by histology of multiple organs before and after TCZ treatment. A woman in her 60s with rheumatoid arthritis was referred to our hospital because of cardiac and renal dysfunction. A gastric and renal biopsy revealed the deposition of AA amyloid, and echocardiography revealed concentric left ventricular hypertrophy. Her estimated glomerular filtration rate was decreased to 8.6 mL/min/1.73 m2, and B-type natriuretic peptide, C-reactive protein, and serum amyloid A protein were significantly elevated. TCZ treatments markedly decreased her serum amyloid A protein and C-reactive protein levels, but hemodialysis was required 1 year later. Endoscopic gastric rebiopsy 3 years after initiation of TCZ treatments revealed the regression of amyloid deposition and echocardiography revealed improvement of her left ventricular hypertrophy. However, a renal rebiopsy revealed that the amyloid deposition had not regressed. In conclusion, these observations suggest that the therapeutic effects of TCZ can vary among organs in patients with AA amyloidosis.

  5. Astrometric studies of the regions BD + 17 degree 4946, BD -5 degree 3071, and Ross 730-1

    International Nuclear Information System (INIS)

    Russell, J.; Gatewood, G.

    1975-01-01

    Positions, proper motions, and absolute parallaxes were found for 46 stars in the regions of BD +17 degree4946, BD -5 degree3071, and Ross 730-1. BD +17 degree4946 showed some evidence of irregular variations in position and magnitude. The residuals for Ross 730-1 were used in a preliminary study to test for an appropriate weighting system; a weak weighting system was indicated. (auth)

  6. Exact sampling of graphs with prescribed degree correlations

    Science.gov (United States)

    Bassler, Kevin E.; Del Genio, Charo I.; Erdős, Péter L.; Miklós, István; Toroczkai, Zoltán

    2015-08-01

    Many real-world networks exhibit correlations between the node degrees. For instance, in social networks nodes tend to connect to nodes of similar degree and conversely, in biological and technological networks, high-degree nodes tend to be linked with low-degree nodes. Degree correlations also affect the dynamics of processes supported by a network structure, such as the spread of opinions or epidemics. The proper modelling of these systems, i.e., without uncontrolled biases, requires the sampling of networks with a specified set of constraints. We present a solution to the sampling problem when the constraints imposed are the degree correlations. In particular, we develop an exact method to construct and sample graphs with a specified joint-degree matrix, which is a matrix providing the number of edges between all the sets of nodes of a given degree, for all degrees, thus completely specifying all pairwise degree correlations, and additionally, the degree sequence itself. Our algorithm always produces independent samples without backtracking. The complexity of the graph construction algorithm is {O}({NM}) where N is the number of nodes and M is the number of edges.

  7. Genome-wide Selective Sweeps in Natural Bacterial Populations Revealed by Time-series Metagenomics

    Energy Technology Data Exchange (ETDEWEB)

    Chan, Leong-Keat; Bendall, Matthew L.; Malfatti, Stephanie; Schwientek, Patrick; Tremblay, Julien; Schackwitz, Wendy; Martin, Joel; Pati, Amrita; Bushnell, Brian; Foster, Brian; Kang, Dongwan; Tringe, Susannah G.; Bertilsson, Stefan; Moran, Mary Ann; Shade, Ashley; Newton, Ryan J.; Stevens, Sarah; McMcahon, Katherine D.; Mamlstrom, Rex R.

    2014-05-12

    Multiple evolutionary models have been proposed to explain the formation of genetically and ecologically distinct bacterial groups. Time-series metagenomics enables direct observation of evolutionary processes in natural populations, and if applied over a sufficiently long time frame, this approach could capture events such as gene-specific or genome-wide selective sweeps. Direct observations of either process could help resolve how distinct groups form in natural microbial assemblages. Here, from a three-year metagenomic study of a freshwater lake, we explore changes in single nucleotide polymorphism (SNP) frequencies and patterns of gene gain and loss in populations of Chlorobiaceae and Methylophilaceae. SNP analyses revealed substantial genetic heterogeneity within these populations, although the degree of heterogeneity varied considerably among closely related, co-occurring Methylophilaceae populations. SNP allele frequencies, as well as the relative abundance of certain genes, changed dramatically over time in each population. Interestingly, SNP diversity was purged at nearly every genome position in one of the Chlorobiaceae populations over the course of three years, while at the same time multiple genes either swept through or were swept from this population. These patterns were consistent with a genome-wide selective sweep, a process predicted by the ecotype model? of diversification, but not previously observed in natural populations.

  8. Genome-wide Selective Sweeps in Natural Bacterial Populations Revealed by Time-series Metagenomics

    Energy Technology Data Exchange (ETDEWEB)

    Chan, Leong-Keat; Bendall, Matthew L.; Malfatti, Stephanie; Schwientek, Patrick; Tremblay, Julien; Schackwitz, Wendy; Martin, Joel; Pati, Amrita; Bushnell, Brian; Foster, Brian; Kang, Dongwan; Tringe, Susannah G.; Bertilsson, Stefan; Moran, Mary Ann; Shade, Ashley; Newton, Ryan J.; Stevens, Sarah; McMahon, Katherine D.; Malmstrom, Rex R.

    2014-06-18

    Multiple evolutionary models have been proposed to explain the formation of genetically and ecologically distinct bacterial groups. Time-series metagenomics enables direct observation of evolutionary processes in natural populations, and if applied over a sufficiently long time frame, this approach could capture events such as gene-specific or genome-wide selective sweeps. Direct observations of either process could help resolve how distinct groups form in natural microbial assemblages. Here, from a three-year metagenomic study of a freshwater lake, we explore changes in single nucleotide polymorphism (SNP) frequencies and patterns of gene gain and loss in populations of Chlorobiaceae and Methylophilaceae. SNP analyses revealed substantial genetic heterogeneity within these populations, although the degree of heterogeneity varied considerably among closely related, co-occurring Methylophilaceae populations. SNP allele frequencies, as well as the relative abundance of certain genes, changed dramatically over time in each population. Interestingly, SNP diversity was purged at nearly every genome position in one of the Chlorobiaceae populations over the course of three years, while at the same time multiple genes either swept through or were swept from this population. These patterns were consistent with a genome-wide selective sweep, a process predicted by the ‘ecotype model’ of diversification, but not previously observed in natural populations.

  9. A review of forensic science higher education programs in the United States: bachelor's and master's degrees.

    Science.gov (United States)

    Tregar, Kristen L; Proni, Gloria

    2010-11-01

    As the number of forensic science programs offered at higher education institutions rises, and more students express an interest in them, it is important to gain information regarding the offerings in terms of courses, equipment available to students, degree requirements, and other important aspects of the programs. A survey was conducted examining the existing bachelor's and master's forensic science programs in the U.S. Of the responding institutions, relatively few were, at the time of the survey, accredited by the forensic science Education Programs Accreditation Commission (FEPAC). In general, the standards of the responding programs vary considerably primarily in terms of their size and subjects coverage. While it is clear that the standards for the forensic science programs investigated are not homogeneous, the majority of the programs provide a strong science curriculum, faculties with advanced degrees, and interesting forensic-oriented courses. © 2010 American Academy of Forensic Sciences.

  10. ALICE Zero Degree Calorimeter

    CERN Multimedia

    De Marco, N

    2013-01-01

    Two identical sets of calorimeters are located on both sides with respect to the beam Interaction Point (IP), 112.5 m away from it. Each set of detectors consists of a neutron (ZN) and a proton (ZP) Zero Degree Calorimeter (ZDC), positioned on remotely controlled platforms. The ZN is placed at zero degree with respect to the LHC beam axis, between the two beam pipes, while the ZP is positioned externally to the outgoing beam pipe. The spectator protons are separated from the ion beams by means of the dipole magnet D1.

  11. The time-varying correlation between policy uncertainty and stock returns: Evidence from China

    Science.gov (United States)

    Xiong, Xiong; Bian, Yuxiang; Shen, Dehua

    2018-06-01

    In this paper, we use a new policy uncertainty index to investigate the time-varying correlation between economic policy uncertainty (EPU) and Chinese stock market returns. The correlation is examined in the period from January 1995 to December 2016. We show that absolute changes in EPU have a significant impact on stock market returns. Specifically, empirical results based on the DCC-GARCH model reveal that the correlation between EPU and stock returns has large fluctuations, especially during a financial crisis; in addition, the impact of EPU on the Shanghai stock market is greater than on the Shenzhen stock market. Robustness results reveal that the impact of EPU on state-owned enterprises is larger than on non-state enterprises. All of these results highlight the important role of EPU in the Chinese stock market, and shed light on such issues for future research.

  12. Large-area imaging reveals biologically driven non-random spatial patterns of corals at a remote reef

    Science.gov (United States)

    Edwards, Clinton B.; Eynaud, Yoan; Williams, Gareth J.; Pedersen, Nicole E.; Zgliczynski, Brian J.; Gleason, Arthur C. R.; Smith, Jennifer E.; Sandin, Stuart A.

    2017-12-01

    For sessile organisms such as reef-building corals, differences in the degree of dispersion of individuals across a landscape may result from important differences in life-history strategies or may reflect patterns of habitat availability. Descriptions of spatial patterns can thus be useful not only for the identification of key biological and physical mechanisms structuring an ecosystem, but also by providing the data necessary to generate and test ecological theory. Here, we used an in situ imaging technique to create large-area photomosaics of 16 plots at Palmyra Atoll, central Pacific, each covering 100 m2 of benthic habitat. We mapped the location of 44,008 coral colonies and identified each to the lowest taxonomic level possible. Using metrics of spatial dispersion, we tested for departures from spatial randomness. We also used targeted model fitting to explore candidate processes leading to differences in spatial patterns among taxa. Most taxa were clustered and the degree of clustering varied by taxon. A small number of taxa did not significantly depart from randomness and none revealed evidence of spatial uniformity. Importantly, taxa that readily fragment or tolerate stress through partial mortality were more clustered. With little exception, clustering patterns were consistent with models of fragmentation and dispersal limitation. In some taxa, dispersion was linearly related to abundance, suggesting density dependence of spatial patterning. The spatial patterns of stony corals are non-random and reflect fundamental life-history characteristics of the taxa, suggesting that the reef landscape may, in many cases, have important elements of spatial predictability.

  13. Zhang neural network for online solution of time-varying convex quadratic program subject to time-varying linear-equality constraints

    International Nuclear Information System (INIS)

    Zhang Yunong; Li Zhan

    2009-01-01

    In this Letter, by following Zhang et al.'s method, a recurrent neural network (termed as Zhang neural network, ZNN) is developed and analyzed for solving online the time-varying convex quadratic-programming problem subject to time-varying linear-equality constraints. Different from conventional gradient-based neural networks (GNN), such a ZNN model makes full use of the time-derivative information of time-varying coefficient. The resultant ZNN model is theoretically proved to have global exponential convergence to the time-varying theoretical optimal solution of the investigated time-varying convex quadratic program. Computer-simulation results further substantiate the effectiveness, efficiency and novelty of such ZNN model and method.

  14. Research Degrees as Professional Education?

    Science.gov (United States)

    Barnacle, Robyn; Dall'Alba, Gloria

    2011-01-01

    There is an increasing trend within higher education and, more specifically, in higher degrees by research, to treat a professional skills set as a desirable graduate outcome. The increasing value that is being placed on a professional skills set in large part reflects growing interest around the world in the role of research degrees in labour…

  15. Control-focused, nonlinear and time-varying modelling of dielectric elastomer actuators with frequency response analysis

    International Nuclear Information System (INIS)

    Jacobs, William R; Dodd, Tony J; Anderson, Sean R; Wilson, Emma D; Porrill, John; Assaf, Tareq; Rossiter, Jonathan

    2015-01-01

    Current models of dielectric elastomer actuators (DEAs) are mostly constrained to first principal descriptions that are not well suited to the application of control design due to their computational complexity. In this work we describe an integrated framework for the identification of control focused, data driven and time-varying DEA models that allow advanced analysis of nonlinear system dynamics in the frequency-domain. Experimentally generated input–output data (voltage-displacement) was used to identify control-focused, nonlinear and time-varying dynamic models of a set of film-type DEAs. The model description used was the nonlinear autoregressive with exogenous input structure. Frequency response analysis of the DEA dynamics was performed using generalized frequency response functions, providing insight and a comparison into the time-varying dynamics across a set of DEA actuators. The results demonstrated that models identified within the presented framework provide a compact and accurate description of the system dynamics. The frequency response analysis revealed variation in the time-varying dynamic behaviour of DEAs fabricated to the same specifications. These results suggest that the modelling and analysis framework presented here is a potentially useful tool for future work in guiding DEA actuator design and fabrication for application domains such as soft robotics. (paper)

  16. Spacetime-varying couplings and Lorentz violation

    International Nuclear Information System (INIS)

    Kostelecky, V. Alan; Lehnert, Ralf; Perry, Malcolm J.

    2003-01-01

    Spacetime-varying coupling constants can be associated with violations of local Lorentz invariance and CPT symmetry. An analytical supergravity cosmology with a time-varying fine-structure constant provides an explicit example. Estimates are made for some experimental constraints

  17. A Gadamerian Phenomenological Study Examining the Meaning of Having a Bachelor's Degree Expressed by Associate Degree Nurses (ADN) Who Educationally Transitioned to a Baccalaureate Degree in Nursing (BSN)

    Science.gov (United States)

    Sauld, Jill Pierpont

    2017-01-01

    Since the inception of associate degree nursing programs, professional nursing conversations and debate have grappled with reckoning differences between the associate degree in nursing (ADN) and the bachelor's degree in nursing (BSN). Research reporting better patient outcomes with more baccalaureate prepared nurses has been a driving force for…

  18. State adaptation reserves cardiorespiratory system first-year students with varying degrees of physical fitness in terms of treadmill test

    Directory of Open Access Journals (Sweden)

    V.A. Levchenko

    2014-05-01

    Full Text Available Purpose : to examine the state of the cardiorespiratory system in terms of the stress test in first-year students with different levels of fitness. Material : the study involved 43 students, of which 18 boys and 25devushek basic medical group. The study used a treadmill, a pulse oximeter, spirometer. Results : more adjustment disorders were detected in students that are not involved in physical education at school. Decreased ability of the cardiorespiratory system to maintain proper oxygen supply of the organism in the stress test. This is not observed in students who were attending school in addition sports clubs. Found that students with low tolerance to physical exercise need a separate program of physical training, the dynamic control of the teachers and the need for additional medical examination. Conclusions : the treadmill test is an ideal way of revealing hidden maladjustment cardiorespiratory system in adolescence.

  19. Musculoskeletal networks reveal topological disparity in mammalian neck evolution.

    Science.gov (United States)

    Arnold, Patrick; Esteve-Altava, Borja; Fischer, Martin S

    2017-12-13

    The increase in locomotor and metabolic performance during mammalian evolution was accompanied by the limitation of the number of cervical vertebrae to only seven. In turn, nuchal muscles underwent a reorganization while forelimb muscles expanded into the neck region. As variation in the cervical spine is low, the variation in the arrangement of the neck muscles and their attachment sites (i.e., the variability of the neck's musculoskeletal organization) is thus proposed to be an important source of neck disparity across mammals. Anatomical network analysis provides a novel framework to study the organization of the anatomical arrangement, or connectivity pattern, of the bones and muscles that constitute the mammalian neck in an evolutionary context. Neck organization in mammals is characterized by a combination of conserved and highly variable network properties. We uncovered a conserved regionalization of the musculoskeletal organization of the neck into upper, mid and lower cervical modules. In contrast, there is a varying degree of complexity or specialization and of the integration of the pectoral elements. The musculoskeletal organization of the monotreme neck is distinctively different from that of therian mammals. Our findings reveal that the limited number of vertebrae in the mammalian neck does not result in a low musculoskeletal disparity when examined in an evolutionary context. However, this disparity evolved late in mammalian history in parallel with the radiation of certain lineages (e.g., cetartiodactyls, xenarthrans). Disparity is further facilitated by the enhanced incorporation of forelimb muscles into the neck and their variability in attachment sites.

  20. Nuclear engineering enrollments and degrees, 1981

    International Nuclear Information System (INIS)

    Little, J.R.; Shirley, D.L.

    1982-05-01

    This report presents data on the number of students enrolled and the degrees awarded in academic year 1980-81 from 73 US institutions offering degree programs in nuclear engineering or nuclear options within other engineering fields. Presented here are historical data for the last decade, which provide information such as trends by degree level, foreign national student participation, female and minority student participation, and placement of graduates. Also included is a listing of the universities by type of program and number of students

  1. Relations Between Positive Impacts Of CSR, External Support, CSR Knowledge And The Degree Of CSR Practices In Thai Small And Medium Enterprises

    OpenAIRE

    Pornpimon Eua-anant; Dusadee Ayuwat; Buapun Promphakping

    2011-01-01

    This article investigates the relations between positive impacts from Corporate Social Responsibility (CSR), external support, knowledge about CSR and the degree of CSR practices according to international standards in the viewpoint of small and medium enterprises in Thailand. The survey among 262 small and medium enterprises in five sections in the northeastern region of Thailand reveals that positive impacts of CSR on internal issues have shown to be positively related to the degree of CSR ...

  2. Combined 30-degree bevel up and down technique against 0-degree phaco tip for phacoemulsification surgery of hard cataracts

    Directory of Open Access Journals (Sweden)

    Joshi RS

    2017-06-01

    Full Text Available Rajesh Subhash Joshi, Sonal Jayant Muley Department of Ophthalmology, Vasantrao Naik Government Medical College, Yavatmal, Maharashtra, India Purpose: To evaluate the effective phaco time (EPT, cumulative dissipated energy (CDE and nucleus emulsification time (NET as phaco parameters with 0- and 30-degree phaco tip. Patients and methods: This prospective, interventional and observational case series included 294 patients scheduled for cataract removal by phacoemulsification technique. Patients with nuclear cataracts of grade 4 and 5 nuclear opalescence of Lens Opacities Classification System III were included in the study. Patients were consecutively allocated to phaco chop technique with 0-degree (0-degree group, n=147 and combined bevel up and down position using 30-degree phaco tip (combined bevel up/down group, n=147. The 0-degree group had phacoemulsification with 0-degree phaco tip, while the 30-degree group had chopping of the nucleus with bevel down phaco tip and emulsification of nuclear fragments was accomplished with bevel up tip. EPT, CDE, NET and intraoperative complications were noted and compared between the groups using analysis of variance. Results: Average EPT, CDE and NET were lower in the 30-degree group than in the 0-degree group. However, no statistically significant difference was found in EPT (P=0.0733, CDE (P=0.0663 and NET (P=0.0633 between the two groups. No serious intraoperative complications were noted. The anterior chamber was maintained throughout the procedure in both groups. No patients had wound burn and miosis during the procedure. None of the patients developed bullous keratopathy, uveitis and cystoid macular edema during the follow-up period. Conclusion: Combined bevel up and down 30-degree tip can yield effective hard nucleus phacoemulsification. Bevel down tip of 30-degree helps in effective chopping and bevel up tip assists in emulsification of the nuclear fragments. Although combined bevel up and down 30

  3. A modified airfoil-based piezoaeroelastic energy harvester with double plunge degrees of freedom

    Directory of Open Access Journals (Sweden)

    Yining Wu

    2016-09-01

    Full Text Available In this letter, a piezoaeroelastic energy harvester based on an airfoil with double plunge degrees of freedom is proposed to additionally take advantage of the vibrational energy of the airfoil pitch motion. An analytical model of the proposed energy harvesting system is built and compared with an equivalent model using the well-explored pitch-plunge configuration. The dynamic response and average power output of the harvester are numerically studied as the flow velocity exceeds the cut-in speed (flutter speed. It is found that the harvester with double-plunge configuration generates 4%–10% more power with varying flow velocities while reducing 6% of the cut-in speed than its counterpart.

  4. Individual Income, Area Deprivation, and Health: Do Income-Related Health Inequalities Vary by Small Area Deprivation?

    Science.gov (United States)

    Siegel, Martin; Mielck, Andreas; Maier, Werner

    2015-11-01

    This paper aims to explore potential associations between health inequalities related to socioeconomic deprivation at the individual and the small area level. We use German cross-sectional survey data for the years 2002 and 2006, and measure small area deprivation via the German Index of Multiple Deprivation. We test the differences between concentration indices of income-related and small area deprivation related inequalities in obesity, hypertension, and diabetes. Our results suggest that small area deprivation and individual income both yield inequalities in health favoring the better-off, where individual income-related inequalities are significantly more pronounced than those related to small area deprivation. We then apply a semiparametric extension of Wagstaff's corrected concentration index to explore how individual-level health inequalities vary with the degree of regional deprivation. We find that the concentration of obesity, hypertension, and diabetes among lower income groups also exists at the small area level. The degree of deprivation-specific income-related inequalities in the three health outcomes exhibits only little variations across different levels of multiple deprivation for both sexes. Copyright © 2014 John Wiley & Sons, Ltd.

  5. Variation in meroplankton along 78 degrees E Meridian

    Digital Repository Service at National Institute of Oceanography (India)

    Balachandran, T.; Peter, K.J.

    Variations along the meridian 78 degrees E between 8 degrees N and 25 degrees S, based on 43 zooplankton samples were studied. Fish larvae exhibited fluctuations in abundance (26 to 57 specimens/IOSN haul) in the three zones studied (8 degrees N-5...

  6. Association between attendance and overall academic performance on a module within a professional pharmacy degree.

    Science.gov (United States)

    Irwin, Nigel; Burnett, Kathryn M; McCarron, Paul A

    2018-03-01

    As the higher education (HE) classroom begins to adopt newer internet-based technologies, the relationship between attendance and performance needs to be re-evaluated, particularly for professional degree courses such as pharmacy. In the present study, we aimed to establish if an association exists between attendance at all timetabled classes and academic performance, in a Clinical Pharmacology and Therapeutics (CPT) module, as part of the Master of Pharmacy (MPharm) degree course at Ulster University. Data on attendance, final examination and coursework performance were collected over two academic years (2013-14 and 2014-15) of the CPT module at Ulster. In total 67 students were analysed. The MPharm degree at Ulster University implements an attendance policy, both as a pastoral support tool and to reinforce the need for professional conduct as a pharmacist. Student (2013-14 and 2014-15, n = 35 and 32, respectively) attendance on the module across both year groups was approximately 80%. We observed positive, and statistically significant relationships between attendance and performance on the examination, and especially in the coursework elements of the module. Student failure (below 40%) in the final examination was linked to attendance below an 80% threshold in nine of 12 cases. Reasons for not attending class varied, but illness was unquestionably the most commonly cited extenuation. Taken together, these data confirm a convincing association between student attendance and academic achievement. Our studies promote the use of attendance monitoring policies for professional degree courses such as pharmacy. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Multiple degree of freedom inverted pendulum dynamics: Modeling, computation, and experimentation

    Science.gov (United States)

    Chen, Cheng-Yuan Jerry

    A pendulum is statically unstable in its upright inverted state due to the Earth's gravitational attraction which points downward. However, with proper forcing, the pendulum can be stabilized in its upright inverted state. Special interest is on periodic vertical forcing applied to the pendulum's base to stabilize it around the upright inverted equilibrium. Many researchers have studied how to stabilize the system by varying various parameters, in particular its amplitude and frequency. Most have focused on the single degree of freedom inverted pendulum case, which with linear assumption can be described via Mathieu's equation. The system stability can then be characterized by Floquet theory. Our focus is on searching for the periodic solutions inside the linearly stable region of the pendulum's inverted state when the pendulum is under proper periodic forcing. Our research shows that under appropriate excitation by controlling the forcing amplitude and frequency, the pendulum can maintain certain periodic orbits around its inverted state which we characterize in a systematic way. In this thesis, we applied four different kinds of geometric realizations of the system response: system time traces, system phase portraits, three dimensional views of the system phase portrait as a function of input forcing, and the system's power spectral density diagram. By analyzing these four diagrams simultaneously, we characterize different kinds of multi-frequency periodic behavior around the pendulum's inverted state. To further discuss the effect of the nonlinearity, we applied perturbation techniques using the normalized forcing amplitude as a perturbation parameter to carry out the approximate periodic solutions on a single degree of freedom inverted pendulum nonlinear model. We also discuss the multiple degree of freedom inverted pendulum system. Both numerical simulation and experiments were performed and detailed comparisons are discussed. Our numerical simulations show

  8. Estimation of degree of polymerization of poly-acrylonitrile-grafted carbon nanotubes using Guinier plot of small angle x-ray scattering.

    Science.gov (United States)

    Cho, Hyunjung; Jin, Kyeong Sik; Lee, Jaegeun; Lee, Kun-Hong

    2018-07-06

    Small angle x-ray scattering (SAXS) was used to estimate the degree of polymerization of polymer-grafted carbon nanotubes (CNTs) synthesized using a 'grafting from' method. This analysis characterizes the grafted polymer chains without cleaving them from CNTs, and provides reliable data that can complement conventional methods such as thermogravimetric analysis or transmittance electron microscopy. Acrylonitrile was polymerized from the surface of the CNTs by using redox initiation to produce poly-acrylonitrile-grafted CNTs (PAN-CNTs). Polymerization time and the initiation rate were varied to control the degree of polymerization. Radius of gyration (R g ) of PAN-CNTs was determined using the Guinier plot obtained from SAXS solution analysis. The results showed consistent values according to the polymerization condition, up to a maximum R g  = 125.70 Å whereas that of pristine CNTs was 99.23 Å. The dispersibility of PAN-CNTs in N,N-dimethylformamide was tested using ultraviolet-visible-near infrared spectroscopy and was confirmed to increase as the degree of polymerization increased. This analysis will be helpful to estimate the degree of polymerization of any polymer-grafted CNTs synthesized using the 'grafting from' method and to fabricate polymer/CNT composite materials.

  9. Pyrosequencing reveals highly diverse and species-specific microbial communities in sponges from the Red Sea

    KAUST Repository

    Lee, Onon

    2010-11-18

    Marine sponges are associated with a remarkable array of microorganisms. Using a tag pyrosequencing technology, this study was the first to investigate in depth the microbial communities associated with three Red Sea sponges, Hyrtios erectus, Stylissa carteri and Xestospongia testudinaria. We revealed highly diverse sponge-associated bacterial communities with up to 1000 microbial operational taxonomic units (OTUs) and richness estimates of up to 2000 species. Altogether, 26 bacterial phyla were detected from the Red Sea sponges, 11 of which were absent from the surrounding sea water and 4 were recorded in sponges for the first time. Up to 100 OTUs with richness estimates of up to 300 archaeal species were revealed from a single sponge species. This is by far the highest archaeal diversity ever recorded for sponges. A non-negligible proportion of unclassified reads was observed in sponges. Our results demonstrated that the sponge-associated microbial communities remained highly consistent in the same sponge species from different locations, although they varied at different degrees among different sponge species. A significant proportion of the tag sequences from the sponges could be assigned to one of the sponge-specific clusters previously defined. In addition, the sponge-associated microbial communities were consistently divergent from those present in the surrounding sea water. Our results suggest that the Red Sea sponges possess highly sponge-specific or even sponge-species-specific microbial communities that are resistant to environmental disturbance, and much of their microbial diversity remains to be explored. © 2011 International Society for Microbial Ecology All rights reserved.

  10. An examination of the factors related to women's degree attainment and career goals in science, technology, and mathematics

    Science.gov (United States)

    Nitopi, Marie

    During the last 30 years, women have made tremendous advances in educational attainment especially in post-secondary education. Despite these advances, recent researchers have revealed that women continue to remain underrepresented in attainment of graduate degrees in the sciences. The researcher's purpose in this study was to extend previous research and to develop a model of variables that significantly contribute to persistence in and attainment of a graduate degree and an eventual career in the science, mathematics, or technology professions. Data were collected from the Baccalaureate and Beyond Longitudinal Study (B&B:93/03). Variables in the categories of demographics, academics, finances, values and attitudes toward educational experiences, and future employment were analyzed by t tests and logistic regressions to determine gender differences in graduate degree attainment and career goals by male and female who majored in science, technology and mathematics. Findings supported significant gender differences in expectations for a graduate degree, age at baccalaureate degree attainment, number of science and engineering credits taken, and the value of faculty interactions. Father's education had a significant effect on degree attainment. Women and men had similar expectations at the beginning of their educational career, but women tended to fall short of their degree expectations ten years later. A large proportion of women dropped out of the science pipeline by choosing different occupations after degree completion. Additionally, women earned fewer science and math credits than men. The professions of science and technology are crucial for the nation's economic growth and competitiveness; therefore, additional researchers should focus on retaining both men and women in the STEM professions.

  11. How Adult Online Graduates Portray Their Degree

    Science.gov (United States)

    Hagan, Eric J.

    2013-01-01

    This qualitative case study investigated how adult graduates of online Bachelor's degree programs describe the online aspect of their degree. Online education is promoted as a method for adult students to access the benefits of a college degree. Therefore, it is important for prospective online students, higher education institutions and…

  12. Career Paths for Physics Degree Recipients

    Science.gov (United States)

    Mulvey, Patrick

    Physics degree holders have a diverse set of career opportunities open to them. So what are these opportunities? Where are they employed? How much do they earn? What skills will they need? Physics degrees make up a small proportion of the degrees conferred in the US but they play an important role in meeting workforce needs at many levels. This talk will give an overview of the employment outcomes of physics bachelors, masters and PhDs. It will discuss the diverse set fields they work in and the skills they use.

  13. Degree-based graph construction

    International Nuclear Information System (INIS)

    Kim, Hyunju; Toroczkai, Zoltan; Erdos, Peter L; Miklos, Istvan; Szekely, Laszlo A

    2009-01-01

    Degree-based graph construction is a ubiquitous problem in network modelling (Newman et al 2006 The Structure and Dynamics of Networks (Princeton Studies in Complexity) (Princeton, NJ: Princeton University Press), Boccaletti et al 2006 Phys. Rep. 424 175), ranging from social sciences to chemical compounds and biochemical reaction networks in the cell. This problem includes existence, enumeration, exhaustive construction and sampling questions with aspects that are still open today. Here we give necessary and sufficient conditions for a sequence of nonnegative integers to be realized as a simple graph's degree sequence, such that a given (but otherwise arbitrary) set of connections from an arbitrarily given node is avoided. We then use this result to present a swap-free algorithm that builds all simple graphs realizing a given degree sequence. In a wider context, we show that our result provides a greedy construction method to build all the f-factor subgraphs (Tutte 1952 Can. J. Math. 4 314) embedded within K n setmn S k , where K n is the complete graph and S k is a star graph centred on one of the nodes. (fast track communication)

  14. Competency-Based Business Degree. Issue Brief

    Science.gov (United States)

    Washington State Board for Community and Technical Colleges, 2014

    2014-01-01

    In January 2015, thirteen Washington community colleges launched an online, competency-based business transfer degree--the first in the state's community and technical college system. This issue brief provides answers to commonly asked questions about the new competency-based degree.

  15. Degree connectivity in body dysmorphic disorder and relationships with obsessive and compulsive symptoms.

    Science.gov (United States)

    Beucke, Jan C; Sepulcre, Jorge; Buhlmann, Ulrike; Kathmann, Norbert; Moody, Teena; Feusner, Jamie D

    2016-10-01

    Individuals with body dysmorphic disorder (BDD) and obsessive-compulsive disorder (OCD) are categorized within the same major diagnostic group and both show regional brain hyperactivity in the orbitofrontal cortex (OFC) and the basal ganglia during symptom provocation. While recent studies revealed that degree connectivity of these areas is abnormally high in OCD and positively correlates with symptom severity, no study has investigated degree connectivity in BDD. We used functional magnetic resonance imaging (fMRI) to compare the local and distant degree of functional connectivity in all brain areas between 28 unmedicated BDD participants and 28 demographically matched healthy controls during a face-processing task. Correlational analyses tested for associations between degree connectivity and symptom severity assessed by the BDD version of the Yale-Brown obsessive-compulsive scale (BDD-Y-BOCS). Reduced local amygdalar connectivity was found in participants with BDD. No differences in distant connectivity were found. BDD-Y-BOCS scores significantly correlated with the local connectivity of the posterior-lateral OFC, and distant connectivity of the posterior-lateral and post-central OFC, respectively. These findings represent preliminary evidence that individuals with BDD exhibit brain-behavioral associations related to obsessive thoughts and compulsive behaviors that are highly similar to correlations previously found in OCD, further underscoring their related pathophysiology. This relationship could be further elucidated through investigation of resting-state functional connectivity in BDD, ideally in direct comparison with OCD and other obsessive-compulsive and related disorders. Copyright © 2016 Elsevier B.V. and ECNP. All rights reserved.

  16. Actuator with Multi Degrees of Freedom(Actuator)

    OpenAIRE

    矢野, 智昭; Tomoaki, YANO; 産業技術総合研究所

    2006-01-01

    The advantages, problems and the recent developments of the actuator with multi degrees of freedom are presented. At first, the advantages of the actuator with multi degrees of freedom are described. Next, the problems needed to solve for practical use are presented. The recent applications of the actuator with multi degrees of freedom are also reviewed.

  17. Lens positioner with five degrees of freedom

    International Nuclear Information System (INIS)

    Kobierecki, M.W.; Rienecker, F. Jr.

    1978-01-01

    A device for positioning lenses precisely with five degrees of freedom (three translations and two angular rotations). The unique features of the device are its compact design, large clear aperture, and high degree of positioning accuracy combined with five degrees of freedom in axis motion. Thus, the device provides precision and flexibility in positioning of optical components

  18. High degree modes and instrumental effects

    Energy Technology Data Exchange (ETDEWEB)

    Korzennik, S G [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA (United States); Rabello-Soares, M C; Schou, J [Stanford University, Stanford, CA (United States)], E-mail: skorzennik@cfa.harvard.edu

    2008-10-15

    Full-disk observations taken with the Michelson Doppler Imager (MDI) on board the Solar and Heliospheric Observatory (SOHO) spacecraft, or the upgraded Global Oscillations Network Group (GONG) instruments, have enough spatial resolution to resolve modes up to {iota} = 1000 if not {iota} = 1500. The inclusion of such high-degree modes (i.e., {iota} {<=} 1000) improves dramatically inferences near the surface. Unfortunately, observational and instrumental effects cause the characterization of high degree modes to be quite complicated. Indeed, the characteristics of the solar acoustic spectrum are such that, for a given order, mode lifetimes get shorter and spatial leaks get closer in frequency as the degree of a mode increases. A direct consequence of this property is that individual modes are resolved only at low and intermediate degrees. At high degrees the individual modes blend into ridges and the power distribution of the ridge defines the ridge central frequency, masking the underlying mode frequency. An accurate model of the amplitude of the peaks that contribute to the ridge power distribution is needed to recover the underlying mode frequency from fitting the ridge. We present a detailed discussion of the modeling of the ridge power distribution, and the contribution of the various observational and instrumental effects on the spatial leakage, in the context of the MDI instrument. We have constructed a physically motivated model (rather than an ad hoc correction scheme) that results in a methodology that can produce unbiased estimates of high-degree modes. This requires that the instrumental characteristics are well understood, a task that has turned out to pose a major challenge. We also present our latest results, where most of the known instrumental and observational effects that affect specifically high-degree modes were removed. These new results allow us to focus our attention on changes with solar activity. Finally, we present variations of mode

  19. Meson degrees of freedom in nuclei

    International Nuclear Information System (INIS)

    Delorme, J.

    1982-01-01

    A review is presented of the successes and shortcomings of the theory of meson degrees of freedom in nuclei with special emphasis on recent progress and on the necessity to bridge the gap with the degrees of freedom of QCD theory. (orig.)

  20. Properties analysis of tensile strength, crystallinity degree and microstructure of polymer composite polypropylene-sand

    International Nuclear Information System (INIS)

    Sudirman; Karo-Karo, Aloma; Ari-Handayani; Bambang-Sugeng; Rukihati; Mashuri

    2004-01-01

    Materials modification base on polymer toward polymer composite is needed by addition of filler. Mechanical properties such as tensile strength, crystallinity degree and microstructure of polymer composite based on polypropylene with sand filler have been investigated. In this work, the polymer composite has been made by mixing the matrix of polypropylene melt flow 2 (PP MF2) or polypropylene melt flow 10 (PP MF 10) with sand filler in a labo plastomill. The composition of sand filler was varied to 10, 30, 40 and 50 % v/v, a then the composite were casted to the film sheets form. The sheets were characterized mechanically i.e tensile strength, crystallinity degree and microstructure. The result showed that the tensile strength decreased by increasing the volume fraction of sand filler, in accordance with microstructure investigation that the matrix area under zone plastic deformation (more cracks), while the filler experienced elastic deformation, so that the strength mechanism of filler did not achieved with expectation (Danusso and Tieghi theory). For filler more than 30 % of volume fraction, the tensile strength of polypropylene melt flow 10 (PP MF 10) was greater than that polypropylene melt flow 2 (PP MF2). It was caused by plasticities in PP MF 10. The tensile strength of PP MF2 was greater than that PP MF 10 for volume fraction of sand filler less than 30 %. It was caused by PP MF2 to be have more degree of crystallinity

  1. Astronomy Enrollments and Degrees: Results from the 2012 Survey of Astronomy Enrollments and Degrees. Focus On

    Science.gov (United States)

    Mulvey, Patrick; Nicholson, Starr

    2014-01-01

    Interest in astronomy degrees in the U.S. remains strong, with astronomy enrollments at or near all-time highs for the 2012-13 academic year. The total number of students taking an introductory astronomy course at a degree-granting physics or astronomy department is approaching 200,000. Enrollments in introductory astronomy courses have been…

  2. Effect of packaging type during postmortem aging and degree of doneness on pork chop sensory traits of loins selected to vary in color and marbling.

    Science.gov (United States)

    Klehm, B J; King, D A; Dilger, A C; Shackelford, S D; Boler, D D

    2018-05-04

    The objective was to determine the interactions between packaging type and degree of doneness on sensory traits of pork loins classified based on the newly proposed USDA quality grades. A total of 144 loins were selected from 2 groups of pigs (lean growth or meat quality production focus) to represent as much variation in visual color and marbling as possible. Selection was achieved with a VQG grading camera. The ventral surface of the loins was evaluated for loin quality traits at 1 d postmortem. At 2 d postmortem loins were sliced into 28-mm-thick chops. Chop within each loin was randomly assigned to either individual vacuum packages or to individual Styrofoam trays and overwrapped in polyvinyl chloride (PVC) oxygen permeable film. Overwrapped PVC packages were then placed in bulk packages and flushed with a gas mixture that contained approximately 0.4% carbon monoxide, 30% carbon dioxide, and 80% nitrogen. Vacuum-packaged chops were aged until 14 d postmortem. Chops packaged in PVC overwrap were aged until 9 d postmortem in the bulk packages, then placed on simulated retail display until 14 d postmortem. Chops from each packaging type were cooked to an internal temperature of either 63 °C or 71 °C for the evaluation of slice shear force (SSF) or for evaluation of tenderness, juiciness, and flavor by a trained panel. Data were analyzed as split-split plot design with production focus of the pigs, proposed USDA quality grade, packaging type, and degree of doneness as fixed effects. While there were main effect differences between production focuses, there were no interactions with production focus. There were also no 3-way (P ≥ 0.19) interactions and only one 2-way interaction among quality grade, packaging type, or degree of doneness. There were no differences in sensory tenderness (P = 0.30), juiciness (P = 0.49), flavor (P = 0.89), SSF (P = 0.13), or cook loss (P = 0.06) among USDA quality grades. There were no differences in sensory tenderness (P = 0

  3. Branding the bio/biomedical engineering degree.

    Science.gov (United States)

    Voigt, Herbert F

    2011-01-01

    The future challenges to medical and biological engineering, sometimes referred to as biomedical engineering or simply bioengineering, are many. Some of these are identifiable now and others will emerge from time to time as new technologies are introduced and harnessed. There is a fundamental issue regarding "Branding the bio/biomedical engineering degree" that requires a common understanding of what is meant by a B.S. degree in Biomedical Engineering, Bioengineering, or Biological Engineering. In this paper we address some of the issues involved in branding the Bio/Biomedical Engineering degree, with the aim of clarifying the Bio/Biomedical Engineering brand.

  4. Genetic algorithm–based varying parameter linear quadratic regulator control for four-wheel independent steering vehicle

    Directory of Open Access Journals (Sweden)

    Linlin Gao

    2015-11-01

    Full Text Available From the perspective of vehicle dynamics, the four-wheel independent steering vehicle dynamics stability control method is studied, and a four-wheel independent steering varying parameter linear quadratic regulator control system is proposed with the help of expert control method. In the article, a four-wheel independent steering linear quadratic regulator controller for model following purpose is designed first. Then, by analyzing the four-wheel independent steering vehicle dynamic characteristics and the influence of linear quadratic regulator control parameters on control performance, a linear quadratic regulator control parameter adjustment strategy based on vehicle steering state is proposed to achieve the adaptive adjustment of linear quadratic regulator control parameters. In addition, to further improve the control performance, the proposed varying parameter linear quadratic regulator control system is optimized by genetic algorithm. Finally, simulation studies have been conducted by applying the proposed control system to the 8-degree-of-freedom four-wheel independent steering vehicle dynamics model. The simulation results indicate that the proposed control system has better performance and robustness and can effectively improve the stability and steering safety of the four-wheel independent steering vehicle.

  5. Efficient approximations of dispersion relations in optical waveguides with varying refractive-index profiles.

    Science.gov (United States)

    Li, Yutian; Zhu, Jianxin

    2015-05-04

    In this paper we consider the problem of computing the eigen-modes for the varying refractive-index profile in an open waveguide. We first approximate the refractive-index by a piecewise polynomial of degree two, and the corresponding Sturm-Liouville problem (eigenvalue problem) of the Helmholtz operator in each layer can be solved analytically by the Kummer functions. Then, analytical approximate dispersion equations are established for both TE and TM cases. Furthermore, the approximate dispersion equations converge fast to the exact ones for the continuous refractive-index function as the maximum value of the subinterval sizes tends to zero. Suitable numerical methods, such as Müller's method or the chord secant method, may be applied to the dispersion relations to compute the eigenmodes. Numerical simulations show that our method is very practical and efficient for computing eigenmodes.

  6. Data on ground-water quality for the Lovelock 1 degree by 2 degree quadrangle, western Nevada

    Science.gov (United States)

    Welch, Alan H.; Williams, Rhea P.

    1987-01-01

    Water quality data for groundwater has been compiled for the Lovelock 1 degree x 2 degree quadrangle which covers a portion of western Nevada. Chemical characteristics of the water are shown on a map (at a scale of 1:250,000) and on trilinear diagrams for the major ions. The data for the area are also presented in a table. (USGS)

  7. Effect of the degree of sternal depression on the cardiac rotation in pectus excavatum: evaluation with spiral CT

    International Nuclear Information System (INIS)

    Yu Jianqun; Yang Zhigang; Li Zhenlin; Guo Yingkun; Lu Chunyan; Zhang Mei

    2004-01-01

    Objective: To evaluate the effects of the degree of sternal depression on the cardiac rotation in pectus excavatum by using spiral CT. Methods: Spiral CT features of 32 patients with surgically corrected pectus excavatum were retrospectively reviewed. They included 27 males and 5 females ranging in age from 6 months to 17 years (mean, 6.3 years). Analysis was based on relationship among the degree of sternal depression, CT depression index, cardiac rotation angle, and PV angle. Results: 32 cases of pectus excavatum presented the sternal depression (21 ± 7) mm, CT depression index 2.9 ± 1.8, cardiac rotation angle (55.9 ± 9.8) degree, and PV angle (49.8 ± 14.0) degree, respectively. The sternal depression (17 mm) in cases with CT depression index less than 2.4 was smaller than those with CT depression index 2.4-2.9 (21 mm) and CT depression index larger than 2.9 (27 mm) (F 5.39, P<0.01). Cardiac rotation angle (49.7 degree) in cases with CT depression index less than 2.4 was smaller than those with CT depression index 2.4-2.9 (55.5 degree) and CT depression index larger than 2.9 (66.9 degree) (F=7.44, P<0.01). PV angle (58.7 degree) in cases with CT depression index less than 2.4 was larger than those with CT depression index 2.4-2.9 (46.5 degree) and CT depression index more than 2.9 (42.4 degree) ( F=3.33, P<0.05). Cardiac rotation angle of pectus excavatum had positive correlation with the CT depression index (γ=0.73, P<0.01). Conclusion: Spiral CT is a better tool for revealing chest deformity and corresponding cardiac rotation. The degree of sternal depression in pectus excavatum directly influences the cardiac rotation, and they had positive correlation. (authors)

  8. Evaluation of quality of mango cultivar Tommy Atkins radiated with greater degree of maturity

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Josenilda M. da, E-mail: jmnilda@cnen.gov.br [Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE/CNEN-PE), Recife, PE (Brazil); Santos, Marilia C.G. dos; Maciel, Maria Ines S., E-mail: marines@ufrpe.br [Universidade Federal Rural de Pernambuco (UFRPE), Recife, PE (Brazil); Villar, Heldio P., E-mail: hpvillar@cnen.gov.br [Escola Politecnica de Pernambuco, Recife, PE (Brazil)

    2011-07-01

    The effects of ionizing radiation at doses of 0.5 and 1.0 kGy were evaluated in mango cultivar Tommy Atkins when harvested at maturation stage showing yellow flesh and skin color more red than green, representing four degree of maturation at commercial scale. The fruits were stored for 21 days at 12 degree C and sensory evaluated after that period as its external appearance, internal appearance, acidic taste, sweet taste, mellow flavor, aroma, texture and succulence of the flesh, by a team of ten trained judges. Physic chemical analysis of the main characteristics of fruits quality were also performed in the pulp at the end of storage. The results of sensory analysis revealed that the doses used did not damaged the sensory characteristics of mango fruit and that they received a dose of 0.5 kGy showed higher acceptance for most sensory attributes evaluated. The physic chemical characteristics showed no significant differences between the doses, except the amount of ascorbic acid that decreased progressively with increasing doses. Application of this method is viable for mango cultivar Tommy Atkins when taken with a higher degree of maturity and was safe for the external market and sensory acceptable. (author)

  9. Evaluation of quality of mango cultivar Tommy Atkins radiated with greater degree of maturity

    International Nuclear Information System (INIS)

    Silva, Josenilda M. da; Santos, Marilia C.G. dos; Maciel, Maria Ines S.; Villar, Heldio P.

    2011-01-01

    The effects of ionizing radiation at doses of 0.5 and 1.0 kGy were evaluated in mango cultivar Tommy Atkins when harvested at maturation stage showing yellow flesh and skin color more red than green, representing four degree of maturation at commercial scale. The fruits were stored for 21 days at 12 degree C and sensory evaluated after that period as its external appearance, internal appearance, acidic taste, sweet taste, mellow flavor, aroma, texture and succulence of the flesh, by a team of ten trained judges. Physic chemical analysis of the main characteristics of fruits quality were also performed in the pulp at the end of storage. The results of sensory analysis revealed that the doses used did not damaged the sensory characteristics of mango fruit and that they received a dose of 0.5 kGy showed higher acceptance for most sensory attributes evaluated. The physic chemical characteristics showed no significant differences between the doses, except the amount of ascorbic acid that decreased progressively with increasing doses. Application of this method is viable for mango cultivar Tommy Atkins when taken with a higher degree of maturity and was safe for the external market and sensory acceptable. (author)

  10. Contribution of counterions and degree of ionization for birefringence creation and relaxation kinetics parameters of PAH/PAZO films

    Energy Technology Data Exchange (ETDEWEB)

    Raposo, Maria, E-mail: mfr@fct.unl.pt; Monteiro Timóteo, Ana Rita; Ribeiro, Paulo A. [CEFITEC, Departamento de Física, Faculdade de Ciências e Tecnologia, UNL, Campus de Caparica, 2829-516 Caparica (Portugal); Ferreira, Quirina [CEFITEC, Departamento de Física, Faculdade de Ciências e Tecnologia, UNL, Campus de Caparica, 2829-516 Caparica (Portugal); Instituto de Telecomunicações, Instituto Superior Técnico, University of Lisbon, Av. Rovisco Pais, P-1049-001 Lisboa (Portugal); Botelho do Rego, Ana Maria [Centro de Química-Física Molecular and IN, Complexo Interdisciplinar, Instituto Superior Técnico, University of Lisbon, 1049-001 Lisboa (Portugal)

    2015-09-21

    Photo induced birefringent materials can be used to develop optical and conversion energy devices, and consequently, the study of the variables that influences the creation and relaxation of birefringence should be carefully analyzed. In this work, the parameters of birefringence creation and relaxation kinetics curves obtained on layer-by-layer (LBL) films, prepared from azo-polyectrolyte poly[1-[4-(3-carboxy-4 hydroxyphenylazo) benzene sulfonamido]-1,2-ethanediyl, sodium salt] (PAZO) and poly(allylamine hydrochloride)(PAH), are related with the presence of counterions and the degree of ionization of the polyelectrolytes. Those kinetics curves obtained on PAH/PAZO LBL films, prepared from PAH solutions with different pHs and maintaining the pH of PAZO solution constant at pH = 9, were analyzed taking into account the films composition which was characterized by X-ray photoelectron spectroscopy. The creation and relaxation birefringence curves are justified by two processes: one associated to local mobility of the azobenzene with a characteristic time 30 s and intensity constant and other associated with polymeric chains mobility with the characteristic time and intensity decreasing with pH. These results allow us to conclude that the birefringence creation process, associated to local mobility of azobenzenes is independent of the degree of ionization and of number of counterions or co-ions present while the birefringence creation process associated to mobility of chains have its characteristic time and intensity dependent of both degree of ionization and number of counterions. The birefringence relaxation processes are dependent of the degree of ionization. The analysis of the films composition revealed, in addition, the presence of a protonated secondary or tertiary amine revealing that PAZO may have positive charges and consequently a zwitterionic behavior.

  11. Contribution of counterions and degree of ionization for birefringence creation and relaxation kinetics parameters of PAH/PAZO films

    International Nuclear Information System (INIS)

    Raposo, Maria; Monteiro Timóteo, Ana Rita; Ribeiro, Paulo A.; Ferreira, Quirina; Botelho do Rego, Ana Maria

    2015-01-01

    Photo induced birefringent materials can be used to develop optical and conversion energy devices, and consequently, the study of the variables that influences the creation and relaxation of birefringence should be carefully analyzed. In this work, the parameters of birefringence creation and relaxation kinetics curves obtained on layer-by-layer (LBL) films, prepared from azo-polyectrolyte poly[1-[4-(3-carboxy-4 hydroxyphenylazo) benzene sulfonamido]-1,2-ethanediyl, sodium salt] (PAZO) and poly(allylamine hydrochloride)(PAH), are related with the presence of counterions and the degree of ionization of the polyelectrolytes. Those kinetics curves obtained on PAH/PAZO LBL films, prepared from PAH solutions with different pHs and maintaining the pH of PAZO solution constant at pH = 9, were analyzed taking into account the films composition which was characterized by X-ray photoelectron spectroscopy. The creation and relaxation birefringence curves are justified by two processes: one associated to local mobility of the azobenzene with a characteristic time 30 s and intensity constant and other associated with polymeric chains mobility with the characteristic time and intensity decreasing with pH. These results allow us to conclude that the birefringence creation process, associated to local mobility of azobenzenes is independent of the degree of ionization and of number of counterions or co-ions present while the birefringence creation process associated to mobility of chains have its characteristic time and intensity dependent of both degree of ionization and number of counterions. The birefringence relaxation processes are dependent of the degree of ionization. The analysis of the films composition revealed, in addition, the presence of a protonated secondary or tertiary amine revealing that PAZO may have positive charges and consequently a zwitterionic behavior

  12. Stratification of living organisms in ballast tanks: how do organism concentrations vary as ballast water is discharged?

    Science.gov (United States)

    First, Matthew R; Robbins-Wamsley, Stephanie H; Riley, Scott C; Moser, Cameron S; Smith, George E; Tamburri, Mario N; Drake, Lisa A

    2013-05-07

    Vertical migrations of living organisms and settling of particle-attached organisms lead to uneven distributions of biota at different depths in the water column. In ballast tanks, heterogeneity could lead to different population estimates depending on the portion of the discharge sampled. For example, concentrations of organisms exceeding a discharge standard may not be detected if sampling occurs during periods of the discharge when concentrations are low. To determine the degree of stratification, water from ballast tanks was sampled at two experimental facilities as the tanks were drained after water was held for 1 or 5 days. Living organisms ≥50 μm were counted in discrete segments of the drain (e.g., the first 20 min of the drain operation, the second 20 min interval, etc.), thus representing different strata in the tank. In 1 and 5 day trials at both facilities, concentrations of organisms varied among drain segments, and the patterns of stratification varied among replicate trials. From numerical simulations, the optimal sampling strategy for stratified tanks is to collect multiple time-integrated samples spaced relatively evenly throughout the discharge event.

  13. Grain-boundary oxidation of used CANDU fuel exposed to dry air at 150 degrees C for a prolonged period

    International Nuclear Information System (INIS)

    Hocking, W.H.; Behnke, R.; Duclos, A.M.

    1995-01-01

    The grain-boundary chemistry of used CANDU fuel exposed to dry air at 150 degrees C for a prolonged period has been investigated by X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM). High degrees of surface oxidation have been determined using the chemical-shift effects for the uranium photoelectron emission, but these must be largely restricted to thin films. The observed distribution of segregated fission products implies an absence of major fuel restructuring and SEM examinations revealed mainly subtle changes in the UO 2 grain structure. These findings are consistent with metallographic evidence of pervasive grain-boundary attack, despite only slight bulk alteration of the fluorite-lattice structure. (author)

  14. Strategies for Pursuing a Master's Degree.

    Science.gov (United States)

    Thomas, Cynthia M; McIntosh, Constance E; Mensik, Jennifer S

    2016-01-01

    Health care has become very complex and is in a constant state of change. As a result of the evolving change and increasing complexity, a more educated nursing workforce is needed (Dracup K. Master's nursing programs. American Association of Colleges of Nursing. 2015; Institute of Medicine. The Future of Nursing: Leading Change, Advancing Health. 2010). It is now becoming necessary for registered nurses to earn an advanced degree to work at the highest level of their practice authority (Dracup K. Master's nursing programs. American Association of Colleges of Nursing. 2015; Institute of Medicine. The Future of Nursing: Leading Change, Advancing Health. 2010.). Preparing to reenter college may be an overwhelming prospect for some registered nurses seeking an advanced degree. However, there are some simple strategies that may help sort out the many degree options, financial obligations, decisions about brick and mortar versus online learning, commitment to degree completion, and changing career paths. This article will provide the registered nurse valuable information that will assist in the exciting process of returning to college.

  15. Matching Value Propositions with Varied Customer Needs

    DEFF Research Database (Denmark)

    Heikka, Eija-Liisa; Frandsen, Thomas; Hsuan, Juliana

    2018-01-01

    Organizations seek to manage varied customer segments using varied value propositions. The ability of a knowledge-intensive business service (KIBS) provider to formulate value propositions into attractive offerings to varied customers becomes a competitive advantage. In this specific business based...... on often highly abstract service offerings, this requires the provider to have a clear overview of its knowledge and resources and how these can be configured to obtain the desired customization of services. Hence, the purpose of this paper is to investigate how a KIBS provider can match value propositions...... with varied customer needs utilizing service modularity. To accomplish this purpose, a qualitative multiple case study is organized around 5 projects allowing within-case and cross-case comparisons. Our findings describe how through the configuration of knowledge and resources a sustainable competitive...

  16. The degree of irreversibility in deterministic finite automata

    DEFF Research Database (Denmark)

    Axelsen, Holger Bock; Holzer, Markus; Kutrib, Martin

    2016-01-01

    the language, and show that the degree induces a strict infinite hierarchy of languages. We examine how the degree of irreversibility behaves under the usual language operations union, intersection, complement, concatenation, and Kleene star, showing tight bounds (some asymptotically) on the degree....

  17. Varying occurrence of extended-spectrum beta-lactamase bacteria among three produce types

    KAUST Repository

    Toh, Benjamin E. W.

    2017-07-07

    A monitoring effort that spanned across 1.5 years was conducted to examine three types of produce-associated microbiota. The average amount of antibiotic-resistant bacteria recovered from lettuce, tomato, and cucumber was 1.02 × 1010, 2.05 × 107, and 4.78 × 109 cells per 50 g of each produce, respectively. A total of 480 bacterial isolates were obtained and identified from their 16S rRNA genes, revealing isolates that were ubiquitously recovered from all three types of produce. However, sporadic presence of Klebsiella pneumoniae and Acinetobacter baumannii was detected on lettuce and cucumbers but not tomatoes. End-point PCR revealed that the K. pneumoniae and A. baumannii isolates were positive for genes encoding extended spectrum beta-lactamase. Whole genome sequencing of two of the K. pneumoniae isolates further suggested the presence of the blaCTX-M-15 gene in a conjugative plasmid, as well as other antibiotic resistance genes and virulence-associated traits in either conjugative plasmids or the chromosomal genome. Quantitative microbial risk assessment indicated varying levels of ingestion risk associated with different types of produce. In particular, the risk arising from ESBL-positive K. pneumoniae in lettuce, but not in cucumbers or tomatoes, was higher than the acceptable annual risk of 10−4. Practical applications Three types of vegetables were sampled and evaluated over 1.5 years to determine differences in their associated bacterial isolates. Particular emphasis was placed on identifying pathogenic strains that were positive for extended spectrum beta-lactamase (ESBL). Quantitative estimates of the microbial risk associated with the ESBL-positive pathogens showed that different produce types may incur varying levels of ingestion risk. Most of the currently reported ESBL-positive bacterial isolates have been identified in nosocomial environments. However, the carriage of such drug-resistant bacteria in vegetables suggests a possible connection

  18. Time to Degree: A National View of the Time Enrolled and Elapsed for Associate and Bachelor's Degree Earners. (Signature Report No. 11)

    Science.gov (United States)

    Shapiro, Doug; Dundar, Afet; Wakhungu, Phoebe Khasiala; Yuan, Xin; Nathan, Angel; Hwang, Youngsik

    2016-01-01

    This report examines time to degree completion for a cohort of students who earned an associate degree as their first and only postsecondary degree or a bachelor's degree as their first four-year degree between July 1, 2014, and June 30, 2015. Overall, the average time enrolled for associate and bachelor's degree earners was 3.3 years and 5.1…

  19. Degree of solidarity with lifestyle and old age among citizens in the Netherlands: cross-sectional results from the longitudinal SMILE study.

    Science.gov (United States)

    Bonnie, Linda H A; van den Akker, Marjan; van Steenkiste, Ben; Vos, Rein

    2010-12-01

    With the increasing interest in lifestyle, health and consequences of unhealthy lifestyles for the healthcare system, a new kind of solidarity is gaining importance: lifestyle solidarity. While it might not seem fair to let other people pay for the costs arising from an unhealthy lifestyle, it does not seem fair either to punish people for their lifestyle. However, it is not clear how solidarity is assessed by people, when considering disease risks or lifestyle risks. The aim of this study was to investigate the degree of solidarity with lifestyle as well as with other factors that are related to health outcomes-for example, old age-and the relation between this degree of solidarity and various characteristics. This cross-sectional study is part of the Dutch longitudinal SMILE study. Data on the degree of solidarity with different lifestyles and old age, and the relation between the degree of solidarity and various demographic and other variables were obtained in a questionnaire survey. Solidarity with smokers and overweight people was moderate, as was solidarity with older people. Respondents were ambivalent about athletes. Respondents who were younger, male and highly educated, and those with a healthy lifestyle, a small social network, high quality of life and an internal locus of control, showed low solidarity. Solidarity with an unhealthy lifestyle and old age is moderate and the degree of solidarity varies among the different subgroups.

  20. Astronautics Degrees for Space Industry

    Science.gov (United States)

    Gruntman, M.; Brodsky, R.; Erwin, D.; Kunc, J.

    The Astronautics Program (http://astronautics.usc.edu) of the University of Southern California (USC) offers a full set of undergraduate and graduate degree programs in Aerospace Engineering with emphasis in Astronautics. The Bachelor of Science degree program in Astronautics combines basic science and engineering classes with specialized astronautics classes. The Master of Science degree program in Astronautics offers classes in various areas of space technology. The Certificate in Astronautics targets practicing engineers and scientists who enter space-related fields and/or who want to obtain training in specific space-related areas. Many specialized graduate classes are taught by adjunct faculty working at the leading space companies. The Master of Science degree and Certificate are available through the USC Distance Education Network (DEN). Today, the Internet allows us to reach students anywhere in the world through webcasting. The majority of our graduate students, as well as those pursuing the Certificate, work full time as engineers in the space industry and government research and development centers. The new world of distance learning presents new challenges and opens new opportunities. We show how the transformation of distance learning and particularly the introduction of webcasting transform organization of the program and class delivery. We will describe in detail the academic focus of the program, student reach, and structure of program components. Program development is illustrated by the student enrollment dynamics and related industrial trends; the lessons learned emphasize the importance of feedback from the students and from the space industry.

  1. An Experimental Study on the Water-Induced Strength Reduction in Zigong Argillaceous Siltstone with Different Degree of Weathering

    Directory of Open Access Journals (Sweden)

    Yu-chuan Yang

    2016-01-01

    Full Text Available The water-softening property of soft rocks is a key problem in geotechnical engineering. A typical red-bed soft rock (the Zigong argillaceous siltstones with different weathering degree is selected as an example to study the water-softening property and the influence of degree of weathering. A series of mechanical and microstructure tests are carried out to analyze the weathering characteristics and mechanism of the Zigong argillaceous siltstones. The results of mechanical experiments reveal that the water content and the weathering degree of rock specimens both have a weakening effect on the compressive and shear strengths. According to the results of present microstructure tests, the mechanical properties of the Zigong argillaceous siltstones are closely correlated with their physical properties, including internal microstructure and material composition for highly weathered rocks or moderately weathered rocks (in both natural and saturation conditions. Finally, experimental results indicate that the changes of microstructure and internal materials are two main factors that influence rock strength parameters after contacting with water and that these properties reflect the rock weathering degree. In a word, when red-bed soft rocks are encountered in geotechnical engineering, special attention should be paid to presence of water.

  2. How Much Does It Cost Institutions to Produce Stem Degrees? Data Brief. The Price and Cost of Science Degrees Series

    Science.gov (United States)

    Delta Cost Project at American Institutes for Research, 2013

    2013-01-01

    This AIR Data Brief breaks down the "cost per degree" estimates for 28 disciplines, including those in the STEM fields, which among the most expensive degrees to produce. The brief points to ways colleges can change their tuition structure to finance STEM degrees more affordably. This data brief is the fourth of four in the series. (See…

  3. Characteristics of regents college nontraditional nuclear technology degrees

    International Nuclear Information System (INIS)

    DeSain, G.W.

    1989-01-01

    In 1971, the Board of Regents of The University of The State of New York created Regents College Degrees to assess academic knowledge of working adults and award college degrees based on demonstrated knowledge rather than time spent in a college classroom. It was founded on a basic premise that seemed radical to some but which is now widely accepted: What a person knows is more important than how or where that knowledge was acquired. Regents College degrees, therefore, are a different concept of a college: one that is an assessing institution rather than a teaching institution. It has no campus and offers no courses. Students can combine college credits from a variety of different sources int an accredited degree program. Staff and faculty evaluate that credit according to the requirements of the particular degree program. When all requirements are met, the Board or Regents of The University of The State of New York confers the degree

  4. Design of 2D time-varying vector fields.

    Science.gov (United States)

    Chen, Guoning; Kwatra, Vivek; Wei, Li-Yi; Hansen, Charles D; Zhang, Eugene

    2012-10-01

    Design of time-varying vector fields, i.e., vector fields that can change over time, has a wide variety of important applications in computer graphics. Existing vector field design techniques do not address time-varying vector fields. In this paper, we present a framework for the design of time-varying vector fields, both for planar domains as well as manifold surfaces. Our system supports the creation and modification of various time-varying vector fields with desired spatial and temporal characteristics through several design metaphors, including streamlines, pathlines, singularity paths, and bifurcations. These design metaphors are integrated into an element-based design to generate the time-varying vector fields via a sequence of basis field summations or spatial constrained optimizations at the sampled times. The key-frame design and field deformation are also introduced to support other user design scenarios. Accordingly, a spatial-temporal constrained optimization and the time-varying transformation are employed to generate the desired fields for these two design scenarios, respectively. We apply the time-varying vector fields generated using our design system to a number of important computer graphics applications that require controllable dynamic effects, such as evolving surface appearance, dynamic scene design, steerable crowd movement, and painterly animation. Many of these are difficult or impossible to achieve via prior simulation-based methods. In these applications, the time-varying vector fields have been applied as either orientation fields or advection fields to control the instantaneous appearance or evolving trajectories of the dynamic effects.

  5. Evaluating the Intoxicating Degree of Liquor Products with Combinations of Fusel Alcohols, Acids, and Esters.

    Science.gov (United States)

    Xie, Jia; Tian, Xiao-Fei; He, Song-Gui; Wei, Yun-Lu; Peng, Bin; Wu, Zhen-Qiang

    2018-05-23

    To investigate the effects of fusel alcohols on the intoxicating degree of liquor products, formulated liquors (FLs) were prepared by blending 1-propanol, isobutanol, and isoamyl alcohol with ethanol, organic acids, and corresponding ethyl esters to simulate the formula of traditional Chinese liquors. The prepared FLs were submitted for evaluation of their intoxicating degree (ID). The results showed that the fusel alcohols had a biphasic effect on the IDs of the FLs, depending on the comprehensive coordination of the characteristic minor components. The importance of the suitable ratio of alcohols/acids/esters (RAAE) on the IDs was also revealed. Under an optimal ratio level, the fusel alcohols exhibited negligible effects on the IDs of the FLs. Moreover, the ratio of isoamyl alcohol to isobutanol (IA/IB) showed a strong positive correlation to the IDs of the FLs. This study lays a foundation for the potential application in producing low-ID liquor.

  6. A happiness degree predictor using the conceptual data structure for deep learning architectures.

    Science.gov (United States)

    Pérez-Benito, Francisco Javier; Villacampa-Fernández, Patricia; Conejero, J Alberto; García-Gómez, Juan M; Navarro-Pardo, Esperanza

    2017-11-13

    Happiness is a universal fundamental human goal. Since the emergence of Positive Psychology, a major focus in psychological research has been to study the role of certain factors in the prediction of happiness. The conventional methodologies are based on linear relationships, such as the commonly used Multivariate Linear Regression (MLR), which may suffer from the lack of representative capacity to the varied psychological features. Using Deep Neural Networks (DNN), we define a Happiness Degree Predictor (H-DP) based on the answers to five psychometric standardized questionnaires. A Data-Structure driven architecture for DNNs (D-SDNN) is proposed for defining a HDP in which the network architecture enables the conceptual interpretation of psychological factors associated to happiness. Four different neural network configurations have been tested, varying the number of neurons and the presence or absence of bias in the hidden layers. Two metrics for evaluating the influence of conceptual dimensions have been defined and computed: one quantifies the influence weight of the conceptual dimension in absolute terms and the other one pinpoints the direction (positive or negative) of the influence. A cross-sectional survey targeting non-institutionalized adult population residing in Spain was completed by 823 cases. The total of 111 elements of the survey are grouped by socio-demographic data and by five psychometric scales (Brief COPE Inventory, EPQR-A, GHQ-28, MOS-SSS and SDHS) measuring several psychological factors acting one as the outcome (SDHS) and the four others as predictors. Our D-SDNN approach provided a better outcome (MSE: 1.46·10 -2 ) than MLR (MSE: 2.30·10 -2 ), hence improving by 37% the predictive accuracy, and allowing to simulate the conceptual structure. We observe a better performance of Deep Neural Networks (DNN) with respect to traditional methodologies. This demonstrates its capability to capture the conceptual structure for predicting happiness

  7. Parental diabetes status reveals association of mitochondrial DNA haplogroup J1 with type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Wainstein Julio

    2009-06-01

    Full Text Available Abstract Background Although mitochondrial dysfunction is consistently manifested in patients with Type 2 Diabetes mellitus (T2DM, the association of mitochondrial DNA (mtDNA sequence variants with T2DM varies among populations. These differences might stem from differing environmental influences among populations. However, other potentially important considerations emanate from the very nature of mitochondrial genetics, namely the notable high degree of partitioning in the distribution of human mtDNA variants among populations, as well as the interaction of mtDNA and nuclear DNA-encoded factors working in concert to govern mitochondrial function. We hypothesized that association of mtDNA genetic variants with T2DM could be revealed while controlling for the effect of additional inherited factors, reflected in family history information. Methods To test this hypothesis we set out to investigate whether mtDNA genetic variants will be differentially associated with T2DM depending on the diabetes status of the parents. To this end, association of mtDNA genetic backgrounds (haplogroups with T2DM was assessed in 1055 Jewish patients with and without T2DM parents ('DP' and 'HP', respectively. Results Haplogroup J1 was found to be 2.4 fold under-represented in the 'HP' patients (p = 0.0035. These results are consistent with a previous observation made in Finnish T2DM patients. Moreover, assessing the haplogroup distribution in 'DP' versus 'HP' patients having diabetic siblings revealed that haplogroup J1 was virtually absent in the 'HP' group. Conclusion These results imply the involvement of inherited factors, which modulate the susceptibility of haplogroup J1 to T2DM.

  8. Ozone sensitivity to varying greenhouse gases and ozone-depleting substances in CCMI-1 simulations

    Directory of Open Access Journals (Sweden)

    O. Morgenstern

    2018-01-01

    Full Text Available Ozone fields simulated for the first phase of the Chemistry-Climate Model Initiative (CCMI-1 will be used as forcing data in the 6th Coupled Model Intercomparison Project. Here we assess, using reference and sensitivity simulations produced for CCMI-1, the suitability of CCMI-1 model results for this process, investigating the degree of consistency amongst models regarding their responses to variations in individual forcings. We consider the influences of methane, nitrous oxide, a combination of chlorinated or brominated ozone-depleting substances, and a combination of carbon dioxide and other greenhouse gases. We find varying degrees of consistency in the models' responses in ozone to these individual forcings, including some considerable disagreement. In particular, the response of total-column ozone to these forcings is less consistent across the multi-model ensemble than profile comparisons. We analyse how stratospheric age of air, a commonly used diagnostic of stratospheric transport, responds to the forcings. For this diagnostic we find some salient differences in model behaviour, which may explain some of the findings for ozone. The findings imply that the ozone fields derived from CCMI-1 are subject to considerable uncertainties regarding the impacts of these anthropogenic forcings. We offer some thoughts on how to best approach the problem of generating a consensus ozone database from a multi-model ensemble such as CCMI-1.

  9. Ozone Sensitivity to Varying Greenhouse Gases and Ozone-Depleting Substances in CCMI-1 Simulations

    Science.gov (United States)

    Morgenstern, Olaf; Stone, Kane A.; Schofield, Robyn; Akiyoshi, Hideharu; Yamashita, Yousuke; Kinnison, Douglas E.; Garcia, Rolando R.; Sudo, Kengo; Plummer, David A.; Scinocca, John; hide

    2018-01-01

    Ozone fields simulated for the first phase of the Chemistry-Climate Model Initiative (CCMI-1) will be used as forcing data in the 6th Coupled Model Intercomparison Project. Here we assess, using reference and sensitivity simulations produced for CCMI-1, the suitability of CCMI-1 model results for this process, investigating the degree of consistency amongst models regarding their responses to variations in individual forcings. We consider the influences of methane, nitrous oxide, a combination of chlorinated or brominated ozone-depleting substances, and a combination of carbon dioxide and other greenhouse gases. We find varying degrees of consistency in the models' responses in ozone to these individual forcings, including some considerable disagreement. In particular, the response of total-column ozone to these forcings is less consistent across the multi-model ensemble than profile comparisons. We analyse how stratospheric age of air, a commonly used diagnostic of stratospheric transport, responds to the forcings. For this diagnostic we find some salient differences in model behaviour, which may explain some of the findings for ozone. The findings imply that the ozone fields derived from CCMI-1 are subject to considerable uncertainties regarding the impacts of these anthropogenic forcings. We offer some thoughts on how to best approach the problem of generating a consensus ozone database from a multi-model ensemble such as CCMI-1.

  10. Nonlinear systems time-varying parameter estimation: Application to induction motors

    Energy Technology Data Exchange (ETDEWEB)

    Kenne, Godpromesse [Laboratoire d' Automatique et d' Informatique Appliquee (LAIA), Departement de Genie Electrique, IUT FOTSO Victor, Universite de Dschang, B.P. 134 Bandjoun (Cameroon); Ahmed-Ali, Tarek [Ecole Nationale Superieure des Ingenieurs des Etudes et Techniques d' Armement (ENSIETA), 2 Rue Francois Verny, 29806 Brest Cedex 9 (France); Lamnabhi-Lagarrigue, F. [Laboratoire des Signaux et Systemes (L2S), C.N.R.S-SUPELEC, Universite Paris XI, 3 Rue Joliot Curie, 91192 Gif-sur-Yvette (France); Arzande, Amir [Departement Energie, Ecole Superieure d' Electricite-SUPELEC, 3 Rue Joliot Curie, 91192 Gif-sur-Yvette (France)

    2008-11-15

    In this paper, an algorithm for time-varying parameter estimation for a large class of nonlinear systems is presented. The proof of the convergence of the estimates to their true values is achieved using Lyapunov theories and does not require that the classical persistent excitation condition be satisfied by the input signal. Since the induction motor (IM) is widely used in several industrial sectors, the algorithm developed is potentially useful for adjusting the controller parameters of variable speed drives. The method proposed is simple and easily implementable in real-time. The application of this approach to on-line estimation of the rotor resistance of IM shows a rapidly converging estimate in spite of measurement noise, discretization effects, parameter uncertainties (e.g. inaccuracies on motor inductance values) and modeling inaccuracies. The robustness analysis for this IM application also revealed that the proposed scheme is insensitive to the stator resistance variations within a wide range. The merits of the proposed algorithm in the case of on-line time-varying rotor resistance estimation are demonstrated via experimental results in various operating conditions of the induction motor. The experimental results obtained demonstrate that the application of the proposed algorithm to update on-line the parameters of an adaptive controller (e.g. IM and synchronous machines adaptive control) can improve the efficiency of the industrial process. The other interesting features of the proposed method include fault detection/estimation and adaptive control of IM and synchronous machines. (author)

  11. Study of selected phenotype switching strategies in time varying environment

    Energy Technology Data Exchange (ETDEWEB)

    Horvath, Denis, E-mail: horvath.denis@gmail.com [Centre of Interdisciplinary Biosciences, Institute of Physics, Faculty of Science, P.J. Šafárik University in Košice, Jesenná 5, 040 01 Košice (Slovakia); Brutovsky, Branislav, E-mail: branislav.brutovsky@upjs.sk [Department of Biophysics, Institute of Physics, P.J. Šafárik University in Košice, Jesenná 5, 040 01 Košice (Slovakia)

    2016-03-22

    Population heterogeneity plays an important role across many research, as well as the real-world, problems. The population heterogeneity relates to the ability of a population to cope with an environment change (or uncertainty) preventing its extinction. However, this ability is not always desirable as can be exemplified by an intratumor heterogeneity which positively correlates with the development of resistance to therapy. Causation of population heterogeneity is therefore in biology and medicine an intensively studied topic. In this paper the evolution of a specific strategy of population diversification, the phenotype switching, is studied at a conceptual level. The presented simulation model studies evolution of a large population of asexual organisms in a time-varying environment represented by a stochastic Markov process. Each organism disposes with a stochastic or nonlinear deterministic switching strategy realized by discrete-time models with evolvable parameters. We demonstrate that under rapidly varying exogenous conditions organisms operate in the vicinity of the bet-hedging strategy, while the deterministic patterns become relevant as the environmental variations are less frequent. Statistical characterization of the steady state regimes of the populations is done using the Hellinger and Kullback–Leibler functional distances and the Hamming distance. - Highlights: • Relation between phenotype switching and environment is studied. • The Markov chain Monte Carlo based model is developed. • Stochastic and deterministic strategies of phenotype switching are utilized. • Statistical measures of the dynamic heterogeneity reveal universal properties. • The results extend to higher lattice dimensions.

  12. Study of selected phenotype switching strategies in time varying environment

    International Nuclear Information System (INIS)

    Horvath, Denis; Brutovsky, Branislav

    2016-01-01

    Population heterogeneity plays an important role across many research, as well as the real-world, problems. The population heterogeneity relates to the ability of a population to cope with an environment change (or uncertainty) preventing its extinction. However, this ability is not always desirable as can be exemplified by an intratumor heterogeneity which positively correlates with the development of resistance to therapy. Causation of population heterogeneity is therefore in biology and medicine an intensively studied topic. In this paper the evolution of a specific strategy of population diversification, the phenotype switching, is studied at a conceptual level. The presented simulation model studies evolution of a large population of asexual organisms in a time-varying environment represented by a stochastic Markov process. Each organism disposes with a stochastic or nonlinear deterministic switching strategy realized by discrete-time models with evolvable parameters. We demonstrate that under rapidly varying exogenous conditions organisms operate in the vicinity of the bet-hedging strategy, while the deterministic patterns become relevant as the environmental variations are less frequent. Statistical characterization of the steady state regimes of the populations is done using the Hellinger and Kullback–Leibler functional distances and the Hamming distance. - Highlights: • Relation between phenotype switching and environment is studied. • The Markov chain Monte Carlo based model is developed. • Stochastic and deterministic strategies of phenotype switching are utilized. • Statistical measures of the dynamic heterogeneity reveal universal properties. • The results extend to higher lattice dimensions.

  13. Nuclear Engineering Enrollments and Degrees Survey, 2005 Data

    International Nuclear Information System (INIS)

    Oak Ridge Institute for Science and Education

    2006-01-01

    This annual report details the number of nuclear engineering bachelor's, master's, and doctoral degrees awarded at a sampling of academic programs from 1998-2005. it also looks at nuclear engineering degrees by curriculum and the number of students enrolled in nuclear engineering degree programs at 30 U.S. universities in 2005

  14. Degree-regular triangulations of torus and Klein bottle

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences; Volume 115; Issue 3 ... A triangulation of a connected closed surface is called degree-regular if each of its vertices have the same degree. ... In [5], Datta and Nilakantan have classified all the degree-regular triangulations of closed surfaces on at most 11 vertices.

  15. Health Physics Enrollments and Degrees Survey, 2005 Data

    International Nuclear Information System (INIS)

    Oak Ridge Institute for Science and Education

    2006-01-01

    This annual report details the number of health physics bachelor's, master's, and postdoctoral degrees awarded at a sampling of academic programs from 1998-2005. It also looks at health physics degrees by curriculum and the number of students enrolled in health physics degree programs at 30 U.S. universities in 2005

  16. Health Physics Enrollments and Degrees Survey, 2004 Data

    International Nuclear Information System (INIS)

    Oak Ridge Institute for Science and Education

    2005-01-01

    This annual report details the number of health physics bachelor's, master's, and doctoral degrees awarded at a sampling of academic programs from 1998-2004. It also looks at health physics degrees by curriculum and the number of students enrolled in health physics degree programs at 28 U.S. universities in 2004

  17. Enhancing mechanical and thermal properties of styrene-butadiene rubber/carboxylated acrylonitrile butadiene rubber blend by the usage of graphene oxide with diverse oxidation degrees

    Science.gov (United States)

    Xue, Xiaodong; Yin, Qing; Jia, Hongbing; Zhang, Xuming; Wen, Yanwei; Ji, Qingmin; Xu, Zhaodong

    2017-11-01

    Graphene oxide (GO) with various oxidation degrees were prepared through a modified Hummer's method by varying the dosage of oxidizing agent. Styrene-butadiene rubber (SBR)/carboxylated acrylonitrile butadiene rubber (XNBR)/GO nanocomposites were fabricated by aqueous-phase mixing of GO colloidal dispersion with SBR latex and a small loading of XNBR latex, followed by co-coagulation. Effects of GO oxidation degree on the morphology, structure, mechanical and thermal properties of nanocomposites were thoroughly investigated. The results showed that the mechanical strength of nanocomposites were enhanced with the increase of oxidation degree of GO. Especially, when the weight ratio of KMnO4 to graphite was 15/5, the tensile strength, tear strength and thermal conductivity of SBR/XNBR/GO filled with 3 phr (parts per hundred rubber) GO increased by 255.3%, 141.5% and 22.8%, respectively, compared to those of neat SBR/XNBR blend. In addition, the thermal stability and the solvent resistance of the nanocomposites were also improved significantly. This work suggested that GO with higher oxidation degree could effectively improve the properties of SBR/XNBR blend.

  18. Gravity and magma induces spreading of Mount Etna volcano revealed by satellite radar interferometry

    Science.gov (United States)

    Lungren, P.; Casu, F.; Manzo, M.; Pepe, A.; Berardino, P.; Sansosti, E.; Lanari, R.

    2004-01-01

    Mount Etna underwent a cycle of eruptive activity over the past ten years. Here we compute ground displacement maps and deformation time series from more than 400 radar interferograms to reveal Mount Etna's average and time varying surface deformation from 1992 to 2001.

  19. Time-varying and time-invariant dimensions of depression in children and adolescents: Implications for cross-informant agreement.

    Science.gov (United States)

    Cole, David A; Martin, Joan M; Jacquez, Farrah M; Tram, Jane M; Zelkowitz, Rachel; Nick, Elizabeth A; Rights, Jason D

    2017-07-01

    The longitudinal structure of depression in children and adolescents was examined by applying a Trait-State-Occasion structural equation model to 4 waves of self, teacher, peer, and parent reports in 2 age groups (9 to 13 and 13 to 16 years old). Analyses revealed that the depression latent variable consisted of 2 longitudinal factors: a time-invariant dimension that was completely stable over time and a time-varying dimension that was not perfectly stable over time. Different sources of information were differentially sensitive to these 2 dimensions. Among adolescents, self- and parent reports better reflected the time-invariant aspects. For children and adolescents, peer and teacher reports better reflected the time-varying aspects. Relatively high cross-informant agreement emerged for the time-invariant dimension in both children and adolescents. Cross-informant agreement for the time-varying dimension was high for adolescents but very low for children. Implications emerge for theoretical models of depression and for its measurement, especially when attempting to predict changes in depression in the context of longitudinal studies. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  20. Design of 2D Time-Varying Vector Fields

    KAUST Repository

    Chen, Guoning

    2012-10-01

    Design of time-varying vector fields, i.e., vector fields that can change over time, has a wide variety of important applications in computer graphics. Existing vector field design techniques do not address time-varying vector fields. In this paper, we present a framework for the design of time-varying vector fields, both for planar domains as well as manifold surfaces. Our system supports the creation and modification of various time-varying vector fields with desired spatial and temporal characteristics through several design metaphors, including streamlines, pathlines, singularity paths, and bifurcations. These design metaphors are integrated into an element-based design to generate the time-varying vector fields via a sequence of basis field summations or spatial constrained optimizations at the sampled times. The key-frame design and field deformation are also introduced to support other user design scenarios. Accordingly, a spatial-temporal constrained optimization and the time-varying transformation are employed to generate the desired fields for these two design scenarios, respectively. We apply the time-varying vector fields generated using our design system to a number of important computer graphics applications that require controllable dynamic effects, such as evolving surface appearance, dynamic scene design, steerable crowd movement, and painterly animation. Many of these are difficult or impossible to achieve via prior simulation-based methods. In these applications, the time-varying vector fields have been applied as either orientation fields or advection fields to control the instantaneous appearance or evolving trajectories of the dynamic effects. © 1995-2012 IEEE.

  1. Design of 2D Time-Varying Vector Fields

    KAUST Repository

    Chen, Guoning; Kwatra, Vivek; Wei, Li-Yi; Hansen, Charles D.; Zhang, Eugene

    2012-01-01

    Design of time-varying vector fields, i.e., vector fields that can change over time, has a wide variety of important applications in computer graphics. Existing vector field design techniques do not address time-varying vector fields. In this paper, we present a framework for the design of time-varying vector fields, both for planar domains as well as manifold surfaces. Our system supports the creation and modification of various time-varying vector fields with desired spatial and temporal characteristics through several design metaphors, including streamlines, pathlines, singularity paths, and bifurcations. These design metaphors are integrated into an element-based design to generate the time-varying vector fields via a sequence of basis field summations or spatial constrained optimizations at the sampled times. The key-frame design and field deformation are also introduced to support other user design scenarios. Accordingly, a spatial-temporal constrained optimization and the time-varying transformation are employed to generate the desired fields for these two design scenarios, respectively. We apply the time-varying vector fields generated using our design system to a number of important computer graphics applications that require controllable dynamic effects, such as evolving surface appearance, dynamic scene design, steerable crowd movement, and painterly animation. Many of these are difficult or impossible to achieve via prior simulation-based methods. In these applications, the time-varying vector fields have been applied as either orientation fields or advection fields to control the instantaneous appearance or evolving trajectories of the dynamic effects. © 1995-2012 IEEE.

  2. Forecasting Financial Extremes: A Network Degree Measure of Super-Exponential Growth.

    Directory of Open Access Journals (Sweden)

    Wanfeng Yan

    Full Text Available Investors in stock market are usually greedy during bull markets and scared during bear markets. The greed or fear spreads across investors quickly. This is known as the herding effect, and often leads to a fast movement of stock prices. During such market regimes, stock prices change at a super-exponential rate and are normally followed by a trend reversal that corrects the previous overreaction. In this paper, we construct an indicator to measure the magnitude of the super-exponential growth of stock prices, by measuring the degree of the price network, generated from the price time series. Twelve major international stock indices have been investigated. Error diagram tests show that this new indicator has strong predictive power for financial extremes, both peaks and troughs. By varying the parameters used to construct the error diagram, we show the predictive power is very robust. The new indicator has a better performance than the LPPL pattern recognition indicator.

  3. Forecasting Financial Extremes: A Network Degree Measure of Super-Exponential Growth.

    Science.gov (United States)

    Yan, Wanfeng; van Tuyll van Serooskerken, Edgar

    2015-01-01

    Investors in stock market are usually greedy during bull markets and scared during bear markets. The greed or fear spreads across investors quickly. This is known as the herding effect, and often leads to a fast movement of stock prices. During such market regimes, stock prices change at a super-exponential rate and are normally followed by a trend reversal that corrects the previous overreaction. In this paper, we construct an indicator to measure the magnitude of the super-exponential growth of stock prices, by measuring the degree of the price network, generated from the price time series. Twelve major international stock indices have been investigated. Error diagram tests show that this new indicator has strong predictive power for financial extremes, both peaks and troughs. By varying the parameters used to construct the error diagram, we show the predictive power is very robust. The new indicator has a better performance than the LPPL pattern recognition indicator.

  4. Time-varying Crash Risk

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Feunoua, Bruno; Jeon, Yoontae

    We estimate a continuous-time model with stochastic volatility and dynamic crash probability for the S&P 500 index and find that market illiquidity dominates other factors in explaining the stock market crash risk. While the crash probability is time-varying, its dynamic depends only weakly on re...

  5. Time varying voltage combustion control and diagnostics sensor

    Science.gov (United States)

    Chorpening, Benjamin T [Morgantown, WV; Thornton, Jimmy D [Morgantown, WV; Huckaby, E David [Morgantown, WV; Fincham, William [Fairmont, WV

    2011-04-19

    A time-varying voltage is applied to an electrode, or a pair of electrodes, of a sensor installed in a fuel nozzle disposed adjacent the combustion zone of a continuous combustion system, such as of the gas turbine engine type. The time-varying voltage induces a time-varying current in the flame which is measured and used to determine flame capacitance using AC electrical circuit analysis. Flame capacitance is used to accurately determine the position of the flame from the sensor and the fuel/air ratio. The fuel and/or air flow rate (s) is/are then adjusted to provide reduced flame instability problems such as flashback, combustion dynamics and lean blowout, as well as reduced emissions. The time-varying voltage may be an alternating voltage and the time-varying current may be an alternating current.

  6. Statistical analysis of two-degree of freedom systems to time history inputs with different durations

    International Nuclear Information System (INIS)

    Lin, C.W.; Li, D.L.

    1987-01-01

    A statistical study is conducted to determine the effect of input time history duration on the response of systems supported by the structure. The model used in the study is a one-degree-of-freedom system mass supported by another one degree of freedom structure mass. The input used is generated from a Monte-Carlo simulation procedure with a prescribed power spectrum density such that the input response spectrum matched the Reg. Guide 1.60 response spectrum. The models were analyzed for different combinations of mass ratios and frequency ratios (ratios of the system versus the supporting structure). Time history inputs used vary from 5 to 20 seconds. Only the 20 second time history matched the Reg. Guide 1.60 response spectrum. Time history inputs shorter than 20 seconds were simply truncated at the tail end. The results of the study indicate that it is necessary to increase the response magnitude by about 20% if a 5-second time history is to be used. For a 10-second input, an increase of 10% will suffice. Whereas for a 15-second input, no adjustment is necessary. (orig./HP)

  7. Subanalysis of the CONFIRM Registries: Acute Procedural Outcomes in Claudicant and Critical Limb Ischemia Patients With Varying Levels of Calcification Treated for Peripheral Arterial Disease With Orbital Atherectomy.

    Science.gov (United States)

    Adams, George L; Das, Tony; Lee, Michael S; Beasley, Robert; Mustapha, Jihad

    2015-11-01

    Patients with peripheral arterial disease (PAD) can be classified into groups based upon the severity of the disease using the Rutherford classification system. This analysis compares the procedural outcomes of PAD patients treated with orbital atherectomy stratified by Rutherford class (1-3 = intermittent claudication; 4-6 = critical limb ischemia [CLI]), and acute angiographic outcomes of these patients stratified by degree of lesion calcification. The CONFIRM registry series was analyzed and included 1697 patients with intermittent claudication (Rutherford class 1-3) and 1320 patients with CLI (Rutherford class 4-6) treated with orbital atherectomy. The composite rate of dissection, perforation, slow-flow, vessel closure, spasm, embolism, and thrombus formation was compared between claudicants and CLI patients with varying degrees of lesion calcification. Patients with CLI were older and had a higher prevalence of diabetes, coronary artery disease, and renal disease (Patherectomy resulted in similar low procedural complication rates in the CLI group compared with the claudicant group. These results suggest that orbital atherectomy is safe and effective for treating calcified lesions in high-risk patients with varying severity of PAD symptoms.

  8. The nanostructures of native celluloses, their transformations upon isolation, and their implications for production of nanocelluloses

    Science.gov (United States)

    Rajai H. Atalla; Rowan S Atalla; Umesh P. Agarwal

    2018-01-01

    Native celluloses in plant cell walls occur in a variety of highly periodic fibrillar forms that have curvature and varying degrees of twist about their longitudinal axes. Though X-ray measurements reveal diffraction patterns, the celluloses are not crystalline in the traditional sense. The diffraction patterns rather are a consequence of the high degree of spatial...

  9. Detection of dynamically varying interaural time differences

    DEFF Research Database (Denmark)

    Kohlrausch, Armin; Le Goff, Nicolas; Breebaart, Jeroen

    2010-01-01

    of fringes surrounding the probe is equal to the addition of the effects of the individual fringes. In this contribution, we present behavioral data for the same experimental condition, called dynamically varying ITD detection, but for a wider range of probe and fringe durations. Probe durations varied...

  10. NMR-Based Metabonomic Investigation of Heat Stress in Myotubes Reveals a Time-Dependent Change in the Metabolites

    DEFF Research Database (Denmark)

    Straadt, Ida K; Young, Jette F; Bross, Peter

    2010-01-01

    NMR-based metabonomics was applied to elucidate the time-dependent stress responses in mouse myotubes after heat exposure of either 42 or 45 degrees C for 1 h. Principal component analysis (PCA) revealed that the gradual time-dependent changes in metabolites contributing to the clustering...... and separation of the control samples from the different time points after heat stress primarily are in the metabolites glucose, leucine, lysine, phenylalanine, creatine, glutamine, and acetate. In addition, PC scores revealed a maximum change in metabolite composition 4 h after the stress exposure; thereafter......, samples returned toward control samples, however, without reaching the control samples even 10 h after stress. The results also indicate that the myotubes efficiently regulate the pH level by release of lactate to the culture medium at a heat stress level of 42 degrees C, which is a temperature level...

  11. Astronomy Enrollments and Degrees: Results from the 2009 & 2010 Surveys of Physics & Astronomy Enrollments and Degrees. Focus On

    Science.gov (United States)

    Nicholson, Starr; Mulvey, Patrick

    2011-01-01

    The Statistical Research Center of the American Institute of Physics conducts an annual census from October through February of all departments that offer degrees in astronomy (78) in the United States. Astronomy departments consist of stand-alone degree-granting departments (39) and departments that are administered along with a physics program…

  12. Impacts of half a degree additional warming on the Asian summer monsoon rainfall characteristics

    Science.gov (United States)

    Lee, Donghyun; Min, Seung-Ki; Fischer, Erich; Shiogama, Hideo; Bethke, Ingo; Lierhammer, Ludwig; Scinocca, John F.

    2018-04-01

    This study investigates the impacts of global warming of 1.5 °C and 2.0 °C above pre-industrial conditions (Paris Agreement target temperatures) on the South Asian and East Asian monsoon rainfall using five atmospheric global climate models participating in the ‘Half a degree Additional warming, Prognosis and Projected Impacts’ (HAPPI) project. Mean and extreme precipitation is projected to increase under warming over the two monsoon regions, more strongly in the 2.0 °C warmer world. Moisture budget analysis shows that increases in evaporation and atmospheric moisture lead to the additional increases in mean precipitation with good inter-model agreement. Analysis of daily precipitation characteristics reveals that more-extreme precipitation will have larger increase in intensity and frequency responding to the half a degree additional warming, which is more clearly seen over the South Asian monsoon region, indicating non-linear scaling of precipitation extremes with temperature. Strong inter-model relationship between temperature and precipitation intensity further demonstrates that the increased moisture with warming (Clausius-Clapeyron relation) plays a critical role in the stronger intensification of more-extreme rainfall with warming. Results from CMIP5 coupled global climate models under a transient warming scenario confirm that half a degree additional warming would bring more frequent and stronger heavy precipitation events, exerting devastating impacts on the human and natural system over the Asian monsoon region.

  13. Adaptive operational modal identification for slow linear time-varying structures based on frozen-in coefficient method and limited memory recursive principal component analysis

    Science.gov (United States)

    Wang, Cheng; Guan, Wei; Wang, J. Y.; Zhong, Bineng; Lai, Xiongming; Chen, Yewang; Xiang, Liang

    2018-02-01

    To adaptively identify the transient modal parameters for linear weakly damped structures with slow time-varying characteristics under unmeasured stationary random ambient loads, this paper proposes a novel operational modal analysis (OMA) method based on the frozen-in coefficient method and limited memory recursive principal component analysis (LMRPCA). In the modal coordinate, the random vibration response signals of mechanical weakly damped structures can be decomposed into the inner product of modal shapes and modal responses, from which the natural frequencies and damping ratios can be well acquired by single-degree-of-freedom (SDOF) identification approach such as FFT. Hence, for the OMA method based on principal component analysis (PCA), it becomes very crucial to examine the relation between the transformational matrix and the modal shapes matrix, to find the association between the principal components (PCs) matrix and the modal responses matrix, and to turn the operational modal parameter identification problem into PCA of the stationary random vibration response signals of weakly damped mechanical structures. Based on the theory of "time-freezing", the method of frozen-in coefficient, and the assumption of "short time invariant" and "quasistationary", the non-stationary random response signals of the weakly damped and slow linear time-varying structures (LTV) can approximately be seen as the stationary random response time series of weakly damped and linear time invariant structures (LTI) in a short interval. Thus, the adaptive identification of time-varying operational modal parameters is turned into decompositing the PCs of stationary random vibration response signals subsection of weakly damped mechanical structures after choosing an appropriate limited memory window. Finally, a three-degree-of-freedom (DOF) structure with weakly damped and slow time-varying mass is presented to illustrate this method of identification. Results show that the LMRPCA

  14. Estimating varying coefficients for partial differential equation models.

    Science.gov (United States)

    Zhang, Xinyu; Cao, Jiguo; Carroll, Raymond J

    2017-09-01

    Partial differential equations (PDEs) are used to model complex dynamical systems in multiple dimensions, and their parameters often have important scientific interpretations. In some applications, PDE parameters are not constant but can change depending on the values of covariates, a feature that we call varying coefficients. We propose a parameter cascading method to estimate varying coefficients in PDE models from noisy data. Our estimates of the varying coefficients are shown to be consistent and asymptotically normally distributed. The performance of our method is evaluated by a simulation study and by an empirical study estimating three varying coefficients in a PDE model arising from LIDAR data. © 2017, The International Biometric Society.

  15. Dependence of balance energy on isospin degrees of freedom

    International Nuclear Information System (INIS)

    Gautam, S.; Sood, Aman D.; Puri, Rajeev K.; Hartnack, Ch.; Aichelin, J.

    2009-01-01

    Collective transverse in-plane flow in heavy ion collisions has been a subject of intensive theoretical and experimental studies, as it can provide information about the nuclear matter equation of state (EOS) as well as in medium nucleon-nucleon (nn) cross section. The study of dependence of collective transverse flow on various entrance channel parameters as beam energy and impact parameter has revealed much interesting physics about the origin and properties of the collective flow. From these studies, it has been found that the transverse in plane flow disappears at an incident energy termed as balance energy (E bal ), where attractive part of the nuclear interactions balances the repulsive part. Presently, due to availability of the radioactive beams, role of isospin degrees of freedom in EOS can be studied. The collective transverse in-plane flow has been found to depend on isospin of the colliding system. Here, we aim to study the dependence of E bal on N/Z ratio of the colliding system using IQMD model

  16. Does the level of emotional intelligence affect the degree of success in nursing studies?

    Science.gov (United States)

    Sharon, Dganit; Grinberg, Keren

    2018-05-01

    Emotional intelligence (EI) reflects the general capacity to comprehend emotions (in ourselves and in others), to regulate emotions, and to cope effectively with emotional situations. The study program in nursing is varied, and includes theoretical and practical aspects, but teaching EI is not part of the core curriculum. We argue that teaching EI should not only be included in the curriculum, but that EI tests should be included in the admissions process. This study reviews the relationship between EI level and the degree of success in nursing studies, and its importance. A convenience sample of 110 academic nursing students was examined. Three data collection methods were employed: 1) A socio-demographic questionnaire; 2) Schutte Self-Report Inventory (SSRI); 3) Psychometric scores and grade transcripts. A positive correlation between the level of EI and the degree of success in nursing studies among nursing students was found. EI levels improved during the second year of learning. Among nursing students, the annual average grade was related to emotional intelligence rather than psychometric scores at the time of admission. There is a need to increase the importance of EI in the terms of nursing student's admission and basic nursing curriculums. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. Evaluating the Intoxicating Degree of Liquor Products with Combinations of Fusel Alcohols, Acids, and Esters

    Directory of Open Access Journals (Sweden)

    Jia Xie

    2018-05-01

    Full Text Available To investigate the effects of fusel alcohols on the intoxicating degree of liquor products, formulated liquors (FLs were prepared by blending 1-propanol, isobutanol, and isoamyl alcohol with ethanol, organic acids, and corresponding ethyl esters to simulate the formula of traditional Chinese liquors. The prepared FLs were submitted for evaluation of their intoxicating degree (ID. The results showed that the fusel alcohols had a biphasic effect on the IDs of the FLs, depending on the comprehensive coordination of the characteristic minor components. The importance of the suitable ratio of alcohols/acids/esters (RAAE on the IDs was also revealed. Under an optimal ratio level, the fusel alcohols exhibited negligible effects on the IDs of the FLs. Moreover, the ratio of isoamyl alcohol to isobutanol (IA/IB showed a strong positive correlation to the IDs of the FLs. This study lays a foundation for the potential application in producing low-ID liquor.

  18. In-homogeneity in the pre-dose sensitization of the 110 Degree-Sign C TL peak in various quartz samples: The influence of annealing

    Energy Technology Data Exchange (ETDEWEB)

    Polymeris, George S., E-mail: polymers@auth.gr [Laboratory of Radiation Applications and Archaeological Dating, Department of Archaeometry and Physicochemical Measurements, Cultural and Educational Technology Institute, Athena, Research and Innovation Center in Information, Communication and Knowledge Technologies, Tsimiski 58, GR-67100 Xanthi (Greece); ISIK University, Faculty of Science and Arts, Physics Department, Sile 34980, Istanbul (Turkey); Oniya, Ebenezer O. [Laboratory of Radiation Applications and Archaeological Dating, Department of Archaeometry and Physicochemical Measurements, Cultural and Educational Technology Institute, Athena, Research and Innovation Center in Information, Communication and Knowledge Technologies, Tsimiski 58, GR-67100 Xanthi (Greece); Physics and Electronics Department, Adekunle Ajasin University, PMB 01 Akungba Akoko (Nigeria); Jibiri, Nnamdi N. [Department of Physics, University of Ibadan, Ibadan (Nigeria); Tsirliganis, Nestor C. [Laboratory of Radiation Applications and Archaeological Dating, Department of Archaeometry and Physicochemical Measurements, Cultural and Educational Technology Institute, Athena, Research and Innovation Center in Information, Communication and Knowledge Technologies, Tsimiski 58, GR-67100 Xanthi (Greece); Kitis, George [Aristotle University of Thessaloniki, Nuclear Physics Laboratory, 54124 Thessaloniki (Greece)

    2012-03-01

    The pre-dose sensitization effect of the 110 Degree-Sign C TL glow-peak of quartz is a basic tool in thermoluminescence and optically stimulated luminescence dating and retrospective dosimetry. In the present work, a homogeneity study was performed on pre-dose sensitization in grains obtained from large quartz crystals samples collected from 10 different origins. The aliquot - to - aliquot scatter of the pre-dose sensitization of the 110 Degree-Sign C TL peak within each quartz crystal was monitored. The influence of the annealing on this scattering was also studied. Therefore, the investigation was applied to the un-fired 'as is' samples as well as to samples annealed at 900 Degree-Sign C for 1 h following cooling to room temperature in air. The results showed that in the case of 'as is' quartz the sensitization effect vary strongly within each aliquot of the same quartz sample. This strong variation is removed by both the high temperature annealing as well as heating up to 500 Degree-Sign C, involved in the TL measurements. These results are generally discussed in the framework of existing models and applications of the effect.

  19. Quasi-monoenergetic neutron energy spectra for 246 and 389 MeV (7)Li(p,n) reactions at angles from 0 degrees to 300 degrees

    CERN Document Server

    Iwamoto, Y; Nakamura, T; Nakashima, H; Mares, V; Itoga, T; Matsumoto, T; Nakane, Y; Feldbaumer, E; Jaegerhofer, L; Pioch, C; Tamii, A; Satoh, D; Masuda, A; Sato, T; Iwase, H; Yashima, H; Nishiyama, J; Hagiwara, M; Hatanaka, K; Sakamoto, Y

    2011-01-01

    The authors measured the neutron energy spectra of a quasi-monoenergetic (7)Li(p,n) neutron source with 246 and 389 MeV protons set at seven angles (0 degrees, 2.5 degrees, 5 degrees, 10 degrees, 15 degrees, 20 degrees and 30 degrees), using a time-of-flight (TOF) method employing organic scintillators NE213 at the Research Center for Nuclear Physics (RCNP) of Osaka University. The energy spectra of the source neutrons were precisely deduced down to 2 MeV at 0 degrees and 10 MeV at other angles. The cross-sections of the peak neutron production reaction at 0 degrees were on the 35-40 mb line of other experimental data, and the peak neutron angular distribution agreed well with the Taddeucci formula. Neutron energy spectra below 100 MeV at all angles were comparable, but the shapes of the continuum above 150 MeV changed considerably with the angle. In order to consider the correction required to derive the response in the peak region from the measured total response for high-energy neutron monitors such as DAR...

  20. Growth of Listeria monocytogenes and Yersinia enterocolitica colonies under modified atmospheres at 4 and 8 degrees C using a model food system.

    Science.gov (United States)

    Harrison, W A; Peters, A C; Fielding, L M

    2000-01-01

    The growth of Listeria monocytogenes and Yersinia enterocolitica colonies was studied on solid media at 4 and 8 degrees C under modified atmospheres (MAs) of 5% O2: 10% CO2: 85% N2 (MA1), 30% CO2: 70% N2 (MA2) and air (control). Colony radius, determined using computer image analysis, allowed specific growth rates (mu) and the time taken to detect bacterial colonies to be estimated, after colonies became visible. At 4 degrees C both MAs decreased the growth rates of L. monocytogenes by 1.5- and 3.0-fold under MA1 (mu = 0.02 h(-1)) and MA2 (mu = 0.01 h(-1)), respectively, as compared with the control (mu = 0.03 h(-1)). The time to detection of bacterial colonies was increased from 15 d (control) to 24 (MA1) and 29 d (MA2). At 8 degrees C MA2 decreased the growth rate by 1.5-fold (mu = 0.04 h(-1)) as compared with the control (mu = 0.06 h(-1)) and detection of colonies increased from 7 (control) to 9 d (MA2). At 4 degrees C both MAs decreased the growth rates of Y. enterocolitica by 1.5- and 2.5-fold under MA1 (mu = 0.03 h(-1)) and MA2 (mu = 0.02 h(-1)), respectively, as compared with the control (mu = 0.05 h(-1)). At 8 degrees C identical growth rates were obtained under MA1 and the control (mu = 0.07 h(-1)) whilst a decrease in the growth rate was obtained under MA2 (mu = 0.04 h(-1)). The detection of colonies varied from 6 (8 degrees C, aerobic) to 19 d (4 degrees C, MA2). Refrigerated modified atmosphere packaged foods should be maintained at 4 degrees C and below to ensure product safety.

  1. Factors affecting attrition from associate degree nursing programs in North Carolina.

    Science.gov (United States)

    Fraher, Erin; Belsky, Daniel W; Gaul, Katie; Carpenter, Jessica

    2010-01-01

    Projected nursing shortfalls have spurred the state of North Carolina to initiate a series of strategies to increase the number of graduates from pre-licensure Registered Nurse (RN) programs. These efforts have been largely successful, but attrition rates from Associate Degree Nursing (ADN) programs remain high. Only 58% of students entering ADN programs complete the degree. While policy makers are keenly aware that attrition from ADN programs is problematic, there is a lack of empirical evidence to identify the specific factors contributing to student attrition. In late 2007, the North Carolina Community College System (NCCCS) asked the Cecil G. Sheps Center for Health Services Research to conduct a study of Associate Degree Nursing program attrition and its causes. This paper summarizes the findings from that study and identifies the student- and program-level characteristics associated with more and less successful ADN programs. While this study was conducted in a single state in the US, the substantive findings--as well as the methodological approach--may be useful to other states and other countries. The study revealed that socioeconomically disadvantaged students (those with GEDs and those who received Pell Grants), non-white students, and younger and older students were less likely to graduate on-time. When programs were grouped into high and low performance categories on the basis of risk adjusted graduation rates, high performing programs were distinguished by more stringent admissions policies and better educated faculties. Nursing shortages have garnered significant attention and resources from state and national workforce planners in recent years. But to date, investments in expanding program capacity have not been matched by attention to program completion rates, with the result that we have enlarged the pipeline without fixing the leaks. Faculty shortages and recession-induced resource constraints limit further program expansion. Addressing attrition

  2. New varying speed of light theories

    CERN Document Server

    Magueijo, J

    2003-01-01

    We review recent work on the possibility of a varying speed of light (VSL). We start by discussing the physical meaning of a varying $c$, dispelling the myth that the constancy of $c$ is a matter of logical consistency. We then summarize the main VSL mechanisms proposed so far: hard breaking of Lorentz invariance; bimetric theories (where the speeds of gravity and light are not the same); locally Lorentz invariant VSL theories; theories exhibiting a color dependent speed of light; varying $c$ induced by extra dimensions (e.g. in the brane-world scenario); and field theories where VSL results from vacuum polarization or CPT violation. We show how VSL scenarios may solve the cosmological problems usually tackled by inflation, and also how they may produce a scale-invariant spectrum of Gaussian fluctuations, capable of explaining the WMAP data. We then review the connection between VSL and theories of quantum gravity, showing how ``doubly special'' relativity has emerged as a VSL effective model of quantum space...

  3. Abnormal intrinsic functional hubs in alcohol dependence: evidence from a voxelwise degree centrality analysis

    Directory of Open Access Journals (Sweden)

    Luo X

    2017-07-01

    Full Text Available Xiaoping Luo,1,2 Linghong Guo,1 Xi-Jian Dai,3 Qinglai Wang,2 Wenzhong Zhu,2 Xinjun Miao,2 Honghan Gong1 1Department of Radiology, The First Affiliated Hospital of Nanchang University, Nangchang, Jiangxi, People’s Republic of China; 2Department of Radiology, Wenzhou Chinese Medicine Hospital, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, People’s Republic of China Objective: To explore the abnormal intrinsic functional hubs in alcohol dependence using voxelwise degree centrality analysis approach, and their relationships with clinical features.Materials and methods: Twenty-four male alcohol dependence subjects free of medicine (mean age, 50.21±9.62 years and 24 age- and education-matched male healthy controls (mean age, 50.29±8.92 years were recruited. The alcohol use disorders identification test and the severity of alcohol dependence questionnaire (SADQ were administered to assess the severity of alcohol craving. Voxelwise degree centrality approach was used to assess the abnormal intrinsic functional hubs features in alcohol dependence. Simple linear regression analysis was performed to investigate the relationships between the clinical features and abnormal intrinsic functional hubs.Results: Compared with healthy controls, alcohol dependence subjects exhibited significantly different degree centrality values in widespread left lateralization brain areas, including higher degree centrality values in the left precentral gyrus (BA 6, right hippocampus (BA 35, 36, and left orbitofrontal cortex (BA 11 and lower degree centrality values in the left cerebellum posterior lobe, bilateral secondary visual network (BA 18, and left precuneus (BA 7, 19. SADQ revealed a negative linear correlation with the degree centrality value in the left precentral gyrus (R2=0.296, P=0.006.Conclusion: The specific abnormal intrinsic functional hubs appear

  4. DNA from radiation resistant human tumor cells transfers resistance to NIH/3T3 cells with varying degrees of penetrance

    International Nuclear Information System (INIS)

    Kasid, U.; Dritschilo, A.; Weichselbaum, R.

    1987-01-01

    Experimental evidence suggests that clinical radiation resistance may correlate with in vitro radiation survival parameters. Specifically, they isolated several cell lines from radioresistant head and neck carcinomas with D/sub 0/ values greater than 2 Gy. The authors co-transfected DNA from cell line SQ2OB (D/sub 0/ = 2.4 Gy) with the rhoSVNeO plasmid into NIH/3T3 cells (D/sub 0/ = 1.7 Gy). Antibiotic G418 resistant, transformed clones were isolated and confirmed by Southern blotting to contain human alu, as well as rhoSVNeO sequences. Screening for radiation resistance with 8Gy (Cs-137) revealed that 3 of 4 tested hybrid clones show a radiation survival intermediate between NIH/3T3 and SQ2OB. This suggests that radiation resistance is a dominant, transfectable phenotype of mammalian cells and can be expressed in more sensitive cells. Karyotyping of resistant hybrid clones shows the presence of double minute chromosomes. Secondary transfection results and experiments to clone the genetic factors responsible for radiation resistance are in progress and results will be reported

  5. Increasingly Global: Combining an International Business Degree with a Post-Degree Designation

    Science.gov (United States)

    Smith, Rachel; Terry, Andy; Vibhakar, Ashvin

    2006-01-01

    In the increasingly complex and competitive global marketplace, many students seek to gain multiple skills and credentials that can aid them in their career goals. One such career strategy weds a general overarching comprehensive degree with a specific and targeted skill set. This paper provides a viable curriculum path for students who seek…

  6. Evaluation of the degree of dispersion of organoclay on nanocomposites with PP/EPDM; Avaliacao do grau de dispersao de argilas organofilicas em nanocompositos de PP/EPDM

    Energy Technology Data Exchange (ETDEWEB)

    Braga, F.C.F.; Oliveira, M.G., E-mail: fernanda.braga@int.gov.b [Instituto Nacional de Tecnologia (DPCM/INT), Rio de Janeiro, RJ (Brazil). Div. de Processamento e Caracterizacao de Materiais; Furtado, C.R.G. [Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ (Brazil)

    2010-07-01

    Nanocomposites of thermoplastic elastomer (TPE) composed by PP/EPDM 1/1 blend and organoclay were obtained by the melt intercalation in an internal chamber mix. Initially, a masterbatch of maleinized polypropylene (PP-MA) and clay modified with alkyl ammonium salt in the ratio 3:1 was prepared, and then, added to TPE matrix to obtain loads of 2,5; 5 and 7 wt% of clay in the nanocomposite. The dispersion degree of clay in TPE matrix was evaluated by X-ray diffraction and parallel plate rheometry. The intercalation/exfoliate degree or the degree of dispersion varied with clay content, as observed by X-ray diffraction. This behavior was confirmed by the profile of the curves of elastic modulus versus frequency, which presented different slopes in the region of low frequency, due to the presence of clay and PP-MA. (author)

  7. Ultrasound evaluation of fluid in knee recesses at varying degrees of flexion

    DEFF Research Database (Denmark)

    Mandl, P; Brossard, M; Aegerter, P

    2012-01-01

    Various methods are utilized in daily practice to obtain optimal information on effusion in the knee. Our aim is to investigate which scanning position provides the best information about synovial fluid in the knee by using ultrasound and to evaluate the magnitude of difference for measuring syno...

  8. Roster of Astronomy Departments with Enrollment and Degree Data, 2012: Results from the 2012 Survey of Enrollments and Degrees. Focus On

    Science.gov (United States)

    Nicholson, Starr; Mulvey, Patrick J.

    2013-01-01

    The U.S. has experienced a sharp increase in the number of bachelor astronomy degrees awarded in recent years with about twice as many degrees now being awarded than a decade ago. There were 385 astronomy bachelor's degrees awarded in the 2011-12 academic year. The number of astronomy PhDs awarded in recent years is up about 50% from a decade…

  9. On the Anonymity Risk of Time-Varying User Profiles

    Directory of Open Access Journals (Sweden)

    Silvia Puglisi

    2017-04-01

    Full Text Available Websites and applications use personalisation services to profile their users, collect their patterns and activities and eventually use this data to provide tailored suggestions. User preferences and social interactions are therefore aggregated and analysed. Every time a user publishes a new post or creates a link with another entity, either another user, or some online resource, new information is added to the user profile. Exposing private data does not only reveal information about single users’ preferences, increasing their privacy risk, but can expose more about their network that single actors intended. This mechanism is self-evident in social networks where users receive suggestions based on their friends’ activities. We propose an information-theoretic approach to measure the differential update of the anonymity risk of time-varying user profiles. This expresses how privacy is affected when new content is posted and how much third-party services get to know about the users when a new activity is shared. We use actual Facebook data to show how our model can be applied to a real-world scenario.

  10. The correlation between lipids ratio and degree of coronary artery stenosis.

    Science.gov (United States)

    Yang, Dan; Liu, Xianbao; Xiang, Meixiang

    2011-06-01

    The aim of the study was to explore the relationship between lipids ratio and the degree of coronary artery stenosis. According to the Gensini score of inpatients in the Cardiology Department of the Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, China, from January 2008 to June 2010, a total of 207 patients (group 1: control group = 34 patients; group 2: 1-30 score group = 84 patients; group 3: 31-90 score group = 66 patients; and group 4: >90 score group = 23 patients) were enrolled, and the relationship between lipids and the degree of coronary artery stenosis was determined. Our study showed that the severity of coronary lesions was increased with the elevation of low-density lipoprotein cholesterol (LDL-C)/high-density lipoprotein cholesterol (HDL-C), total cholesterol (TC), LDL-C, triglycerides (TG), TC/HDL-C, TG/HDL-C and reduction of HDL-C. Compared with group 1, LDL-C/HDL-C, TC/HDL-C were significantly increased in groups 2, 3 and 4 (p value of TG, TG/HDL-C among groups 2, 3 and 4 (p > 0.05). Furthermore, the Pearson correlation analysis revealed that LDL-C/HDL-C (r = 0.54, p value of TG/HDL-C needs further study. Received for publication 25 October 2010; accepted for publication 14 April 2011.

  11. Doppler-guided hemorrhoidal artery ligation (DG-HAL): a safe treatment of II-III degree hemorrhoids for all patients. Could it be potentially also good prophylaxis?

    Science.gov (United States)

    Testa, A; Torino, G

    2010-06-01

    Doppler-guided hemorrhoidal artery ligation (HAL Doppler) is an innovative hemorrhoid treatment mainly utilised for II-III degree where bleeding is a predominant symptom. This procedure aims at dearterialization of the internal hemorrhoidal plexus by ligation of the terminal branches of the superior rectal artery detected using a special proctoscope and ultrasound system; the procedure is performed entirely above the dentate line, so it is genuinely painless. The aim of this study was to evaluate the efficacy, safety and invasivity of HAL Doppler technique to treat II and III degree hemorrhoids. The authors treated 148 patients, from May 2002 to December 2007, principally affected by II-III degree hemorrhoids characterized by bleeding and pain at evacuation. These patients were examined in a retrospective observational study of 128 patients, 86% of the group. Follow-up varied from 5 up to 72 months with an average observation time of 36.5 months. Success was registered in 90% of patients affected by II-III degree hemorrhoids and the absence of major complications (hemorrhage, incontinence, stenosis, perforation, sepsis). The authors suggest the safety, efficacy and low invasity of HAL Doppler for treatment of II-III degree hemorrhoids, which also found in the literature, and highlight its use in treating patients with unhealthy conditions which are a contraindication to the usual surgical treatments. Moreover, they suppose the use of HAL Doppler in low degree hemorrhoids as a therapeutic and also prophylactic rule of advanced degree.

  12. Geometric Mechanics Reveals Optimal Complex Terrestrial Undulation Patterns

    Science.gov (United States)

    Gong, Chaohui; Astley, Henry; Schiebel, Perrin; Dai, Jin; Travers, Matthew; Goldman, Daniel; Choset, Howie; CMU Team; GT Team

    Geometric mechanics offers useful tools for intuitively analyzing biological and robotic locomotion. However, utility of these tools were previously restricted to systems that have only two internal degrees of freedom and in uniform media. We show kinematics of complex locomotors that make intermittent contacts with substrates can be approximated as a linear combination of two shape bases, and can be represented using two variables. Therefore, the tools of geometric mechanics can be used to analyze motions of locomotors with many degrees of freedom. To demonstrate the proposed technique, we present studies on two different types of snake gaits which utilize combinations of waves in the horizontal and vertical planes: sidewinding (in the sidewinder rattlesnake C. cerastes) and lateral undulation (in the desert specialist snake C. occipitalis). C. cerastes moves by generating posteriorly traveling body waves in the horizontal and vertical directions, with a relative phase offset equal to +/-π/2 while C. occipitalismaintains a π/2 offset of a frequency doubled vertical wave. Geometric analysis reveals these coordination patterns enable optimal movement in the two different styles of undulatory terrestrial locomotion. More broadly, these examples demonstrate the utility of geometric mechanics in analyzing realistic biological and robotic locomotion.

  13. Current Trends in Associate Degree Nursing Programs.

    Science.gov (United States)

    Blackstone, Elaine Grant

    This study was designed to ascertain current trends in associate degree nursing programs and to discover innovative ideas and techniques which could be applied to the existing program at Miami-Dade Community College (Florida). Data was compiled from interviews with representatives of ten associate degree nursing programs in six states. Information…

  14. Requirements of British universities for higher medical degrees.

    OpenAIRE

    Johnson, R

    1991-01-01

    OBJECTIVE--To examine the requirements and opportunities for obtaining a doctor of medicine or master of surgery degree from a university in the United Kingdom other than the graduate's own, particularly in the case of foreign graduates. DESIGN--Review of regulations governing the award of doctor of medicine and master of surgery degrees in British universities. SETTING--All 19 universities in the United Kingdom offering clinical courses. MAIN OUTCOME MEASURE--Availability of degrees to gradu...

  15. Altered reward processing in the orbitofrontal cortex and hippocampus in healthy first-degree relatives of patients with depression

    DEFF Research Database (Denmark)

    Macoveanu, J; Knorr, U; Skimminge, A

    2014-01-01

    BACKGROUND: Healthy first-degree relatives of patients with major depression (rMD+) show brain structure and functional response anomalies and have elevated risk for developing depression, a disorder linked to abnormal serotonergic neurotransmission and reward processing. METHOD: In a two...... intervention compared to placebo. Conversely, for positive outcomes, the left hippocampus showed attenuated response to high wins in the rMD+ compared to the rMD- group. The SSRI intervention reinforced the hippocampal response to large wins. A subsequent structural analysis revealed that the abnormal neural...... responses were not accounted for by changes in gray matter density in rMD+ individuals. CONCLUSIONS: Our study in first-degree relatives of depressive patients showed abnormal brain responses to aversive and rewarding outcomes in regions known to be dysfunctional in depression. We further confirmed...

  16. Protograph LDPC Codes with Node Degrees at Least 3

    Science.gov (United States)

    Divsalar, Dariush; Jones, Christopher

    2006-01-01

    In this paper we present protograph codes with a small number of degree-3 nodes and one high degree node. The iterative decoding threshold for proposed rate 1/2 codes are lower, by about 0.2 dB, than the best known irregular LDPC codes with degree at least 3. The main motivation is to gain linear minimum distance to achieve low error floor. Also to construct rate-compatible protograph-based LDPC codes for fixed block length that simultaneously achieves low iterative decoding threshold and linear minimum distance. We start with a rate 1/2 protograph LDPC code with degree-3 nodes and one high degree node. Higher rate codes are obtained by connecting check nodes with degree-2 non-transmitted nodes. This is equivalent to constraint combining in the protograph. The condition where all constraints are combined corresponds to the highest rate code. This constraint must be connected to nodes of degree at least three for the graph to have linear minimum distance. Thus having node degree at least 3 for rate 1/2 guarantees linear minimum distance property to be preserved for higher rates. Through examples we show that the iterative decoding threshold as low as 0.544 dB can be achieved for small protographs with node degrees at least three. A family of low- to high-rate codes with minimum distance linearly increasing in block size and with capacity-approaching performance thresholds is presented. FPGA simulation results for a few example codes show that the proposed codes perform as predicted.

  17. Structure and origin of the 85 degrees E ridge

    Digital Repository Service at National Institute of Oceanography (India)

    Ramana, M.V.; Subrahmanyam, V.; Chaubey, A.K.; Ramprasad, T.; Sarma, K.V.L.N.S.; Krishna, K.S.; Desa, M.; Murty, G.P.S.; Subrahmanyam, C

    The submerged 85 degrees E Ridge in the Bay of Bengal trends approximately N-S between 19 degrees N and 6 degrees N latitudes. Off the southeast coast of Sri Lanka it takes an arcuate shape and seems to terminate with the northweard extension...

  18. Shrinkage Degree in $L_{2}$ -Rescale Boosting for Regression.

    Science.gov (United States)

    Xu, Lin; Lin, Shaobo; Wang, Yao; Xu, Zongben

    2017-08-01

    L 2 -rescale boosting ( L 2 -RBoosting) is a variant of L 2 -Boosting, which can essentially improve the generalization performance of L 2 -Boosting. The key feature of L 2 -RBoosting lies in introducing a shrinkage degree to rescale the ensemble estimate in each iteration. Thus, the shrinkage degree determines the performance of L 2 -RBoosting. The aim of this paper is to develop a concrete analysis concerning how to determine the shrinkage degree in L 2 -RBoosting. We propose two feasible ways to select the shrinkage degree. The first one is to parameterize the shrinkage degree and the other one is to develop a data-driven approach. After rigorously analyzing the importance of the shrinkage degree in L 2 -RBoosting, we compare the pros and cons of the proposed methods. We find that although these approaches can reach the same learning rates, the structure of the final estimator of the parameterized approach is better, which sometimes yields a better generalization capability when the number of sample is finite. With this, we recommend to parameterize the shrinkage degree of L 2 -RBoosting. We also present an adaptive parameter-selection strategy for shrinkage degree and verify its feasibility through both theoretical analysis and numerical verification. The obtained results enhance the understanding of L 2 -RBoosting and give guidance on how to use it for regression tasks.

  19. Investigation of air-water flow in a horizontal pipe with 90 degree bends using wire mesh sensors

    Energy Technology Data Exchange (ETDEWEB)

    Bowden, R.C.; Yang, S.K., E-mail: robert.bowden@cnl.ca, E-mail: sun-kyu.yang@cnl.ca [Canadian Nuclear Laboratories, Chalk River, ON (Canada)

    2015-07-01

    Wire mesh sensors were used to investigate the void fraction distribution along a 9 meter long, 50.8 mm diameter, horizontal test section that contained two 90 degree bends. Deionised water and compressed air were used as the working fluids, with the bubbly flow regime achieved at a superficial liquid velocity of 3.5 m/s and superficial gas velocities that varied between 0.1 and 1.2 m/s. The effects of superficial gas velocity and axial location on the void fraction distribution were investigated. Bubble and slug flow patterns were identified using a probability density function analysis based on a Gaussian mixture model. (author)

  20. Varying constants, black holes, and quantum gravity

    International Nuclear Information System (INIS)

    Carlip, S.

    2003-01-01

    Tentative observations and theoretical considerations have recently led to renewed interest in models of fundamental physics in which certain 'constants' vary in time. Assuming fixed black hole mass and the standard form of the Bekenstein-Hawking entropy, Davies, Davis and Lineweaver have argued that the laws of black hole thermodynamics disfavor models in which the fundamental electric charge e changes. I show that with these assumptions, similar considerations severely constrain 'varying speed of light' models, unless we are prepared to abandon cherished assumptions about quantum gravity. Relaxation of these assumptions permits sensible theories of quantum gravity with ''varying constants,'' but also eliminates the thermodynamic constraints, though the black hole mass spectrum may still provide some restrictions on the range of allowable models

  1. Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment

    NARCIS (Netherlands)

    J.P. Kemp (John); M.C. Medina-Gomez (Carolina); K. Estrada Gil (Karol); B. St Pourcain (Beate); D.H.M. Heppe (Denise); N.M. Warrington (Nicole); L. Oei (Ling); S.M. Ring (Susan); C.J. Kruithof (Claudia); N.J. Timpson (Nicholas); L.E. Wolber (Lisa); S. Reppe (Sjur); K.M. Gautvik (Kaare); E. Grundberg (Elin); B. Ge (Bing); B.C.J. van der Eerden (Bram); J. van de Peppel (Jeroen); M.A. Hibbs (Matthew); C.L. Ackert-Bicknell (Cheryl); K. Choi (Kunho); D.L. Koller (Daniel); M.J. Econs (Michael); F.M. Williams (Frances); T. Foroud (Tatiana); M.C. Zillikens (Carola); C. Ohlsson (Claes); A. Hofman (Albert); A.G. Uitterlinden (André); G. Davey-Smith (George); V.W.V. Jaddoe (Vincent); J.H. Tobias (Jon); F. Rivadeneira Ramirez (Fernando); D.M. Evans (David)

    2014-01-01

    textabstractHeritability of bone mineral density (BMD) varies across skeletal sites, reflecting different relative contributions of genetic and environmental influences. To quantify the degree to which common genetic variants tag and environmental factors influence BMD, at different sites, we

  2. Maximizing the Spread of Influence via Generalized Degree Discount.

    Science.gov (United States)

    Wang, Xiaojie; Zhang, Xue; Zhao, Chengli; Yi, Dongyun

    2016-01-01

    It is a crucial and fundamental issue to identify a small subset of influential spreaders that can control the spreading process in networks. In previous studies, a degree-based heuristic called DegreeDiscount has been shown to effectively identify multiple influential spreaders and has severed as a benchmark method. However, the basic assumption of DegreeDiscount is not adequate, because it treats all the nodes equally without any differences. To consider a general situation in real world networks, a novel heuristic method named GeneralizedDegreeDiscount is proposed in this paper as an effective extension of original method. In our method, the status of a node is defined as a probability of not being influenced by any of its neighbors, and an index generalized discounted degree of one node is presented to measure the expected number of nodes it can influence. Then the spreaders are selected sequentially upon its generalized discounted degree in current network. Empirical experiments are conducted on four real networks, and the results show that the spreaders identified by our approach are more influential than several benchmark methods. Finally, we analyze the relationship between our method and three common degree-based methods.

  3. Dirac's minimum degree condition restricted to claws

    NARCIS (Netherlands)

    Broersma, Haitze J.; Ryjacek, Z.; Schiermeyer, I.

    1997-01-01

    Let G be a graph on n 3 vertices. Dirac's minimum degree condition is the condition that all vertices of G have degree at least . This is a well-known sufficient condition for the existence of a Hamilton cycle in G. We give related sufficiency conditions for the existence of a Hamilton cycle or a

  4. FINITE ELEMENT ANALYSIS OF TAPERED COMPOSITE PLATE GIRDER WITH A NON-LINEAR VARYING WEB DEPTH

    Directory of Open Access Journals (Sweden)

    Q. A. HASAN

    2017-11-01

    Full Text Available The paper presents Finite Element Analysis to determine the ultimate shear capacity of tapered composite plate girder. The effect of degree of taper on the ultimate shear capacity of tapered steel-concrete composite plate girder with a nonlinear varying web depth, effect of slenderness ratio on the ultimate shear capacity, and effect of flange stiffness on the ductility were considered as the parametric studies. Effect of concrete slab on the ultimate shear capacity of tapered plate girders was also considered and it was found to be so effective on the ultimate shear capacity of the tapered plate girder compared with the steel one. The accuracy of the finite element method is established by comparing the finite element with the results existing in the literature. The study was conducted using nonlinear finite element modelling with computer software LUSAS 14.7.

  5. Spall behavior of cast iron with varying microstructures

    International Nuclear Information System (INIS)

    Plume, Gifford; Rousseau, Carl-Ernst

    2014-01-01

    The spall strength of cast iron with varying microstructures has been investigated using plate impact at moderate speed. Stress history measurements were made with manganin stress gauges embedded between the back face of the specimen and a low impedance polycarbonate backing. Five separate cast irons were tested. Four of these consisted of gray cast iron with graphite in flake form, with three classified as Type VII A2 and the fourth containing a bimodal distribution of Types VII A4 and VII D8. The fifth casting consisted of ductile cast iron with graphite in nodular form, classified as Type I, size class 5. The spall strength for the Type VII A2 gray cast irons varied between 40 and 370 MPa, and that of the additional gray cast iron, between 410 and 490 MPa. The spall strength of the ductile cast iron fell within the range of 0.94–1.2 GPa. It is shown that the spall strength is linked to the damage level at the spall plane, where an increased level of tensile stress is required to generate higher levels of damage. Post mortem analysis was performed on the recovered samples, revealing the graphite phase to be the primary factor governing the spall fracture of cast irons, where crack nucleation is directly correlated to the debonding of graphite from the metal matrix. The average length of graphite found within a casting is linked to the material's strength, where strength increases as a function of decreasing length. The morphology and mean free path of graphite precipitates further govern the subsequent coalescence of initiated cracks to form a complete fracture plane. In cases where graphite spacing is large, increased energy level is required to complete the fracture process. A secondary factor governing the spall fracture of cast irons has also been linked to the microstructure of the metal matrix, with pearlite yielding higher spall strengths than free ferrite.

  6. Spall behavior of cast iron with varying microstructures

    Energy Technology Data Exchange (ETDEWEB)

    Plume, Gifford; Rousseau, Carl-Ernst, E-mail: rousseau@uri.edu [Mechanical Engineering, University of Rhode Island, 92 Upper College Rd., Kingston, Rhode Island 02881 (United States)

    2014-07-21

    The spall strength of cast iron with varying microstructures has been investigated using plate impact at moderate speed. Stress history measurements were made with manganin stress gauges embedded between the back face of the specimen and a low impedance polycarbonate backing. Five separate cast irons were tested. Four of these consisted of gray cast iron with graphite in flake form, with three classified as Type VII A2 and the fourth containing a bimodal distribution of Types VII A4 and VII D8. The fifth casting consisted of ductile cast iron with graphite in nodular form, classified as Type I, size class 5. The spall strength for the Type VII A2 gray cast irons varied between 40 and 370 MPa, and that of the additional gray cast iron, between 410 and 490 MPa. The spall strength of the ductile cast iron fell within the range of 0.94–1.2 GPa. It is shown that the spall strength is linked to the damage level at the spall plane, where an increased level of tensile stress is required to generate higher levels of damage. Post mortem analysis was performed on the recovered samples, revealing the graphite phase to be the primary factor governing the spall fracture of cast irons, where crack nucleation is directly correlated to the debonding of graphite from the metal matrix. The average length of graphite found within a casting is linked to the material's strength, where strength increases as a function of decreasing length. The morphology and mean free path of graphite precipitates further govern the subsequent coalescence of initiated cracks to form a complete fracture plane. In cases where graphite spacing is large, increased energy level is required to complete the fracture process. A secondary factor governing the spall fracture of cast irons has also been linked to the microstructure of the metal matrix, with pearlite yielding higher spall strengths than free ferrite.

  7. External Periodic Force Control of a Single-Degree-of-Freedom Vibroimpact System

    Directory of Open Access Journals (Sweden)

    Jingyue Wang

    2013-01-01

    Full Text Available A single-degree-of-freedom mechanical model of vibro-impact system is established. Bifurcation and chaos in the system are revealed with the time history diagram, phase trajectory map, and Poincaré map. According to the bifurcation and chaos of the actual vibro-impact system, the paper puts forward external periodic force control strategy. The method of controlling chaos by external periodic force feedback controller is developed to guide chaotic motions towards regular motions. The stability of the control system is also analyzed especially by theory. By selecting appropriate feedback coefficients, the unstable periodic orbits of the original chaotic orbit can be stabilized to the stable periodic orbits. The effectiveness of this control method is verified by numerical simulation.

  8. [Neonatal adrenal hemorrhage revealed by jaundice: a case report].

    Science.gov (United States)

    Oulmaati, A; Hays, S; Mory-Thomas, N; Bretones, P; Bensaid, M; Jordan, I; Bonfils, M; Godbert, I; Picaud, J-C

    2012-04-01

    The clinical presentation of adrenal hemorrhage varies, depending on the extent of hemorrhage as well as the amount of adrenal cortex involved by the hemorrhage. We report here a case of neonatal adrenal hemorrhage revealed by late onset of neonatal jaundice. This adrenal hemorrhage most probably resulted from shoulder dystocia. The aim of this work was to focus on the fact that jaundice can be caused by adrenal hemorrhage and to emphasize the crucial importance of abdominal ultrasound in cases of persistent jaundice. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  9. A Degree Distribution Optimization Algorithm for Image Transmission

    Science.gov (United States)

    Jiang, Wei; Yang, Junjie

    2016-09-01

    Luby Transform (LT) code is the first practical implementation of digital fountain code. The coding behavior of LT code is mainly decided by the degree distribution which determines the relationship between source data and codewords. Two degree distributions are suggested by Luby. They work well in typical situations but not optimally in case of finite encoding symbols. In this work, the degree distribution optimization algorithm is proposed to explore the potential of LT code. Firstly selection scheme of sparse degrees for LT codes is introduced. Then probability distribution is optimized according to the selected degrees. In image transmission, bit stream is sensitive to the channel noise and even a single bit error may cause the loss of synchronization between the encoder and the decoder. Therefore the proposed algorithm is designed for image transmission situation. Moreover, optimal class partition is studied for image transmission with unequal error protection. The experimental results are quite promising. Compared with LT code with robust soliton distribution, the proposed algorithm improves the final quality of recovered images obviously with the same overhead.

  10. Epilogue: degrees of transparency

    NARCIS (Netherlands)

    Hengeveld, K.

    2011-01-01

    In this epilogue the results of the analyses of four different languages in the preceding papers are compared. It is shown that the degrees of transparency of these languages can be represented on an implicational scale, and that the features themselves can be ranked on a transparency scale as well.

  11. Degrees of polarization for a quantum field

    International Nuclear Information System (INIS)

    Sanchez-Soto, L L; Soederholm, J; Yustas, E C; Klimov, A B; Bjoerk, G

    2006-01-01

    Unpolarized light is invariant with respect to any SU(2) polarization transformation. Since this fully characterizes the set of density matrices representing unpolarized states, we introduce the degree of polarization of a quantum state as its distance to the set of unpolarized states. We discuss different candidates of distance, and show that they induce fundamentally different degrees of polarization

  12. Degree Output in the South, 1975-76: Distribution by Race.

    Science.gov (United States)

    Mingle, James R.

    The first systematic national count of degree output by race is presented for use by institutional curriculum planners to help give students the opportunity to make realistic choices in career planning. Included are summary tables of degree production by level (doctoral, master's, bachelor's, and first-professional degrees awarded); degree changes…

  13. Making Sense of the Combined Degree Experience: The Example of Criminology Double Degrees

    Science.gov (United States)

    Wimshurst, Kerry; Manning, Matthew

    2017-01-01

    Little research has been undertaken on student experiences of combined degrees. The few studies report that a considerable number of students experienced difficulty with the contrasting epistemic/disciplinary demands of the component programmes. A mixed-methods approach was employed to explore the experiences of graduates from four double degrees…

  14. First discoveries of z ˜ 6 quasars with the Kilo-Degree Survey and VISTA Kilo-Degree Infrared Galaxy survey

    NARCIS (Netherlands)

    Venemans, B. P.; Verdoes Kleijn, G. A.; Mwebaze, J.; Valentijn, E. A.; Bañados, E.; Decarli, R.; de Jong, J. T. A.; Findlay, J. R.; Kuijken, K. H.; Barbera, F. La; Mc Farland, John; McMahon, R. G.; Napolitano, N.; Sikkema, G.; Sutherland, W. J.

    2015-01-01

    We present the results of our first year of quasar search in the ongoing ESO public Kilo-Degree Survey (KiDS) and VISTA Kilo-Degree Infrared Galaxy (VIKING) surveys. These surveys are among the deeper wide-field surveys that can be used to uncover large numbers of z ˜ 6 quasars. This allows us to

  15. Controlled ultrafast transfer and stability degree of generalized coherent states of a kicked two-level ion

    Science.gov (United States)

    Chen, Hao; Kong, Chao; Hai, Wenhua

    2018-06-01

    We investigate quantum dynamics of a two-level ion trapped in the Lamb-Dicke regime of a δ -kicked optical lattice, based on the exact generalized coherent states rotated by a π / 2 pulse of Ramsey type experiment. The spatiotemporal evolutions of the spin-motion entangled states in different parameter regions are illustrated, and the parameter regions of different degrees of quantum stability described by the quantum fidelity are found. Time evolutions of the probability for the ion being in different pseudospin states reveal that the ultrafast entanglement generation and population transfers of the system can be analytically controlled by managing the laser pulses. The probability in an initially disentangled state shows periodic collapses (entanglement) and revivals (de-entanglement). Reduction of the stability degree results in enlarging the period of de-entanglement, while the instability and potential chaos will cause the sustained entanglement. The results could be justified experimentally in the existing setups and may be useful in engineering quantum dynamics for quantum information processing.

  16. Mediation analysis with time varying exposures and mediators.

    Science.gov (United States)

    VanderWeele, Tyler J; Tchetgen Tchetgen, Eric J

    2017-06-01

    In this paper we consider causal mediation analysis when exposures and mediators vary over time. We give non-parametric identification results, discuss parametric implementation, and also provide a weighting approach to direct and indirect effects based on combining the results of two marginal structural models. We also discuss how our results give rise to a causal interpretation of the effect estimates produced from longitudinal structural equation models. When there are time-varying confounders affected by prior exposure and mediator, natural direct and indirect effects are not identified. However, we define a randomized interventional analogue of natural direct and indirect effects that are identified in this setting. The formula that identifies these effects we refer to as the "mediational g-formula." When there is no mediation, the mediational g-formula reduces to Robins' regular g-formula for longitudinal data. When there are no time-varying confounders affected by prior exposure and mediator values, then the mediational g-formula reduces to a longitudinal version of Pearl's mediation formula. However, the mediational g-formula itself can accommodate both mediation and time-varying confounders and constitutes a general approach to mediation analysis with time-varying exposures and mediators.

  17. Astronautics degrees for the space industry

    Science.gov (United States)

    Gruntman, M.; Brodsky, R. F.; Erwin, D. A.; Kunc, J. A.

    2004-01-01

    The Astronautics Program (http://astronautics.usc.edu) of the University of Southern California (USC) offers a full set of undergraduate and graduate degree programs in Aerospace Engineering with emphasis in Astronautics. The Bachelor of Science and Master of Science degree programs in Astronautics combine basic science and engineering classes with specialized classes in space technology. The Certificate in Astronautics targets practicing engineers and scientists who enter space-related fields and/or who want to obtain training in specific space-related areas. Many specialized graduate classes are taught by adjunct faculty working at the leading space companies. The Master of Science degree and Certificate are available entirely through the USC Distance Education Network (DEN). Today, the Internet allows us to reach students anywhere in the world through webcasting. The majority of our graduate students, as well as those pursuing the Certificate, work full time as engineers in the space industry and government research and development centers while earning their degrees. The new world of distance learning presents new challenges and opens new opportunities. Distance learning, and particularly the introduction of webcasting, transform the organization of the graduate program and class delivery. We describe in detail the program's academic focus, student reach, and structure of program components. Program development is illustrated by the student enrollment dynamics and related industrial trends; the lessons learned emphasize the importance of feedback from the students and from the space industry.

  18. Registered Nurse (Associate Degree).

    Science.gov (United States)

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document, which is designed for use in developing a tech prep competency profile for the occupation of registered nurse (with an associate degree), lists technical competencies and competency builders for 19 units pertinent to the health technologies cluster in general and 5 units specific to the occupation of registered nurse. The following…

  19. The Correlation Between Porosity, Density and Degree of Serpentinization in Ophiolites from Point Sal, California: Implications for Strength of Oceanic Lithosphere

    Science.gov (United States)

    Karrasch, A. K.; Farough, A.; Lowell, R. P.

    2017-12-01

    Hydration and serpentinization of oceanic lithosphere influences its strength and behavior under stress. Serpentine content is the limiting factor in deformation and the correlation between crustal strength and the degree of serpentinization is not linear. Escartin et al., [2001] shows that the presence of only 10% serpentine results in a nominally non-dilatant mode of brittle deformation and reduces the strength of peridotites dramatically. In this study, we measured density and porosity of ophiolite samples from Point Sal, CA that had various degrees of serpentinization. The densities ranged between 2500- 3000 kg/m3 and porosities ranged between 2.1-4.8%. The degree of serpentinization was estimated from mineralogical analysis, and these data were combined with that of 4 other samples analyzed by Farough et al., [2016], which were obtained from various localities. The degree of serpentinization varied between 0.6 and 40%. We found that degree of serpentinization was inversely correlated with density with a slope of 7.25 (kg/m3)/%. Using Horen et al., [1996] models, estimated P-wave velocity of the samples ranged between 6.75-7.90 km/s and S-wave velocity ranged between 3.58-4.35 km/s. There were no distinguishable difference in the results between olivine-rich or pyroxene-rich samples. These results, along with correlations to strength and deformation style, can be used as a reference for mechanical properties of the crust at depth, analysis of deep drill cores and to estimate the rate of weakening of the oceanic crust after the onset of serpentinization reactions.

  20. A novel topology control approach to maintain the node degree in dynamic wireless sensor networks.

    Science.gov (United States)

    Huang, Yuanjiang; Martínez, José-Fernán; Díaz, Vicente Hernández; Sendra, Juana

    2014-03-07

    Topology control is an important technique to improve the connectivity and the reliability of Wireless Sensor Networks (WSNs) by means of adjusting the communication range of wireless sensor nodes. In this paper, a novel Fuzzy-logic Topology Control (FTC) is proposed to achieve any desired average node degree by adaptively changing communication range, thus improving the network connectivity, which is the main target of FTC. FTC is a fully localized control algorithm, and does not rely on location information of neighbors. Instead of designing membership functions and if-then rules for fuzzy-logic controller, FTC is constructed from the training data set to facilitate the design process. FTC is proved to be accurate, stable and has short settling time. In order to compare it with other representative localized algorithms (NONE, FLSS, k-Neighbor and LTRT), FTC is evaluated through extensive simulations. The simulation results show that: firstly, similar to k-Neighbor algorithm, FTC is the best to achieve the desired average node degree as node density varies; secondly, FTC is comparable to FLSS and k-Neighbor in terms of energy-efficiency, but is better than LTRT and NONE; thirdly, FTC has the lowest average maximum communication range than other algorithms, which indicates that the most energy-consuming node in the network consumes the lowest power.

  1. Eestlased Karlovy Varys / J. R.

    Index Scriptorium Estoniae

    J. R.

    2007-01-01

    Ilmar Raagi mängufilm "Klass" osaleb 42. Karlovy Vary rahvusvahelise filmifestivali võistlusprogrammis "East of the West" ja Asko Kase lühimängufilm "Zen läbi prügi" on valitud festivali kõrvalprogrammi "Forum of Independents"

  2. Enhanced activation of matrix metalloproteinase-9 correlates with the degree of papillary thyroid carcinoma infiltration

    Science.gov (United States)

    Marečko, Ilona; Cvejić, Dubravka; Šelemetjev, Sonja; Paskaš, Svetlana; Tatić, Svetislav; Paunović, Ivan; Savin, Svetlana

    2014-01-01

    Aim To determine whether matrix metalloproteinase-9 (MMP-9) may be a useful adjunctive tool for predicting unfavorable biological behavior of papillary thyroid carcinoma (PTC) by evaluating the expression profile and proteolytic activity of MMP-9 in PTC by different techniques and correlating the findings with clinicopathological prognostic factors. Methods Immunohistochemical localization of MMP-9 was analyzed with antibodies specific for either total or active MMP-9. Activation ratios of MMP-9 were calculated by quantifying gel zymography bands. Enzymatic activity of MMP-9 was localized by in situ zymography after inhibiting MMP-2 activity. Results Immunostaining of total and active MMP-9 was observed in tumor tissue and occasionally in non-neoplastic epithelium. Only active MMP-9 was significantly associated with extrathyroid invasion, lymph-node metastasis, and the degree of tumor infiltration (P zymography revealed a correlation between the MMP-9 activation ratio and nodal involvement, extrathyroid invasion, and the degree of tumor infiltration. In situ zymography showed that gelatinases exerted their activity in tumor parenchymal and stromal cells. Moreover, after application of MMP-2 inhibitor, the remaining gelatinase activity, corresponding to MMP-9, was highest in cancers with the most advanced degree of tumor infiltration. Conclusions This is the first report suggesting that the evaluation of active MMP-9 by immunohistochemistry and determination of its activation ratio by gelatin zymography may be a useful adjunct to the known clinicopathological factors in predicting tumor behavior. Most important, in situ zimography with an MMP-2 inhibitor for the first time demonstrated a strong impact of MMP-9 activity on the degree of tumor infiltration during PTC progression. PMID:24778099

  3. Abdominal and Pelvic CT

    Medline Plus

    Full Text Available ... fast, painless, noninvasive and accurate. In emergency cases, it can reveal internal injuries and bleeding quickly enough ... parts absorb the x-rays in varying degrees. It is this crucial difference in absorption that allows ...

  4. [Study of the reineta protein modifications (Brama australis), put under freezing and storage to -18 degrees C and -30 degrees C].

    Science.gov (United States)

    Abugoch, Lilian; Quitral, Vilma; Larraín, M Angélica; Vinagre, Julia; Kriukov, Andrei; Chávez, Gloria

    2006-12-01

    The objective of the present work was to study functional and thermal properties of reineta (Brama australis) frozen meat, analysed by water retention capacity (WRC), gel forming capacity (GFC), texture, emulsifying capacity and differential scanning calorimetry (DSC). For this study, reineta fillets were obtained and extracted by the same conditions, and cutted, packaged, frozen and stored at -18 degrees C and -30 degrees C for 7 months. The results obtained, showed that there were no signifficant differences in the responses to thermal treatment for all the specimens. For samples frozen at -18 degrees C and -30 degrees C, the protein contents were 23.5 + 0.0 and 25.4 + 1.0%, respectively. The WRC values were 0.45 + 0.1 and 1.59 +/- 0.0 g water/g protein, respectively. The gel forming capacity was only present in the fresh samples, whereas the frozen stored ones only form protein aggregates. The emulsifying capacity was between 960 and 1400 g oil / g protein, and the storage time increased this value. The miosin denaturation temperature (Td) and denaturation enthalpy (?H), obtained by DSC, fluctuated between 39.2 +/- 0.5 to 44.8 +/- 0.8 degrees C and 1.12 +/- 0.3 to 0.52 +/- 0.2 J/g, respectively. The actina values were between 71.0 +/- 0.6 to 75.3 +/- 0.5 degrees C and between 0.5 +/- 0.1 to 0.7 +/- 0.1 J/g. Cooperativity decreased as the storage time increased. This is showing a certain degree of protein displacement. The values found by thermal analyses showed a direct relationship with the functional properties, both decreasing with storage time.

  5. Developing 360 degree feedback system for KINS

    Energy Technology Data Exchange (ETDEWEB)

    Han, In Soo; Cheon, B. M.; Kim, T. H.; Ryu, J. H. [Chungman National Univ., Daejeon (Korea, Republic of)

    2003-12-15

    This project aims to investigate the feasibility of a 360 degree feedback systems for KINS and to design guiding rules and structures in implementing that systems. Literature survey, environmental analysis and questionnaire survey were made to ensure that 360 degree feedback is the right tool to improve performance in KINS. That review leads to conclusion that more readiness and careful feasibility review are needed before implementation of 360 degree feedback in KINS. Further the project suggests some guiding rules that can be helpful for successful implementation of that system in KINS. Those include : start with development, experiment with one department, tie it to a clear organization's goal, train everyone involve, make sure to try that system in an atmosphere of trust.

  6. Developing 360 degree feedback system for KINS

    International Nuclear Information System (INIS)

    Han, In Soo; Cheon, B. M.; Kim, T. H.; Ryu, J. H.

    2003-12-01

    This project aims to investigate the feasibility of a 360 degree feedback systems for KINS and to design guiding rules and structures in implementing that systems. Literature survey, environmental analysis and questionnaire survey were made to ensure that 360 degree feedback is the right tool to improve performance in KINS. That review leads to conclusion that more readiness and careful feasibility review are needed before implementation of 360 degree feedback in KINS. Further the project suggests some guiding rules that can be helpful for successful implementation of that system in KINS. Those include : start with development, experiment with one department, tie it to a clear organization's goal, train everyone involve, make sure to try that system in an atmosphere of trust

  7. Copula-based modeling of degree-correlated networks

    International Nuclear Information System (INIS)

    Raschke, Mathias; Schläpfer, Markus; Trantopoulos, Konstantinos

    2014-01-01

    Dynamical processes on complex networks such as information exchange, innovation diffusion, cascades in financial networks or epidemic spreading are highly affected by their underlying topologies as characterized by, for instance, degree–degree correlations. Here, we introduce the concept of copulas in order to generate random networks with an arbitrary degree distribution and a rich a priori degree–degree correlation (or ‘association’) structure. The accuracy of the proposed formalism and corresponding algorithm is numerically confirmed, while the method is tested on a real-world network of yeast protein–protein interactions. The derived network ensembles can be systematically deployed as proper null models, in order to unfold the complex interplay between the topology of real-world networks and the dynamics on top of them. (paper)

  8. Radiation protection enrollments and degrees, 1979 and 1980

    International Nuclear Information System (INIS)

    Gove, R.M.; Little, J.R.; Shirley, D.L.

    1981-07-01

    Public concern over the effects of low-level radiation and other aspects of the use of nuclear energy has grown in recent years, and the demand for radiation protection has continued to increase. Radiation Protection Enrollments and Degrees presents the results of the latest survey of institutions offering degree programs in this field. Students obtaining such degrees are vital to the development of industry, medicine, research, power production, construction, and agriculture. These surveys assist state and federal governments in their search for such personnel

  9. Comparison of Linear Microinstability Calculations of Varying Input Realism

    International Nuclear Information System (INIS)

    Rewoldt, G.

    2003-01-01

    The effect of varying ''input realism'' or varying completeness of the input data for linear microinstability calculations, in particular on the critical value of the ion temperature gradient for the ion temperature gradient mode, is investigated using gyrokinetic and gyrofluid approaches. The calculations show that varying input realism can have a substantial quantitative effect on the results

  10. Comparison of linear microinstability calculations of varying input realism

    International Nuclear Information System (INIS)

    Rewoldt, G.; Kinsey, J.E.

    2004-01-01

    The effect of varying 'input realism' or varying completeness of the input data for linear microinstability calculations, in particular on the critical value of the ion temperature gradient for the ion temperature gradient mode, is investigated using gyrokinetic and gyrofluid approaches. The calculations show that varying input realism can have a substantial quantitative effect on the results

  11. Combined risk assessment of nonstationary monthly water quality based on Markov chain and time-varying copula.

    Science.gov (United States)

    Shi, Wei; Xia, Jun

    2017-02-01

    Water quality risk management is a global hot research linkage with the sustainable water resource development. Ammonium nitrogen (NH 3 -N) and permanganate index (COD Mn ) as the focus indicators in Huai River Basin, are selected to reveal their joint transition laws based on Markov theory. The time-varying moments model with either time or land cover index as explanatory variables is applied to build the time-varying marginal distributions of water quality time series. Time-varying copula model, which takes the non-stationarity in the marginal distribution and/or the time variation in dependence structure between water quality series into consideration, is constructed to describe a bivariate frequency analysis for NH 3 -N and COD Mn series at the same monitoring gauge. The larger first-order Markov joint transition probability indicates water quality state Class V w , Class IV and Class III will occur easily in the water body of Bengbu Sluice. Both marginal distribution and copula models are nonstationary, and the explanatory variable time yields better performance than land cover index in describing the non-stationarities in the marginal distributions. In modelling the dependence structure changes, time-varying copula has a better fitting performance than the copula with the constant or the time-trend dependence parameter. The largest synchronous encounter risk probability of NH 3 -N and COD Mn simultaneously reaching Class V is 50.61%, while the asynchronous encounter risk probability is largest when NH 3 -N and COD Mn is inferior to class V and class IV water quality standards, respectively.

  12. Time-varying multiplex network: Intralayer and interlayer synchronization

    Science.gov (United States)

    Rakshit, Sarbendu; Majhi, Soumen; Bera, Bidesh K.; Sinha, Sudeshna; Ghosh, Dibakar

    2017-12-01

    A large class of engineered and natural systems, ranging from transportation networks to neuronal networks, are best represented by multiplex network architectures, namely a network composed of two or more different layers where the mutual interaction in each layer may differ from other layers. Here we consider a multiplex network where the intralayer coupling interactions are switched stochastically with a characteristic frequency. We explore the intralayer and interlayer synchronization of such a time-varying multiplex network. We find that the analytically derived necessary condition for intralayer and interlayer synchronization, obtained by the master stability function approach, is in excellent agreement with our numerical results. Interestingly, we clearly find that the higher frequency of switching links in the layers enhances both intralayer and interlayer synchrony, yielding larger windows of synchronization. Further, we quantify the resilience of synchronous states against random perturbations, using a global stability measure based on the concept of basin stability, and this reveals that intralayer coupling strength is most crucial for determining both intralayer and interlayer synchrony. Lastly, we investigate the robustness of interlayer synchronization against a progressive demultiplexing of the multiplex structure, and we find that for rapid switching of intralayer links, the interlayer synchronization persists even when a large number of interlayer nodes are disconnected.

  13. Health Physics Enrollments and Degrees Survey, 2006 Data

    International Nuclear Information System (INIS)

    Oak Ridge Institute for Science and Education

    2007-01-01

    This annual survey collects 2006 data on the number of health physics degrees awarded as well as the number of students enrolled in health physics academic programs. Thirty universities offer health physics degrees; all responded to the survey

  14. Geometric evolution of complex networks with degree correlations

    Science.gov (United States)

    Murphy, Charles; Allard, Antoine; Laurence, Edward; St-Onge, Guillaume; Dubé, Louis J.

    2018-03-01

    We present a general class of geometric network growth mechanisms by homogeneous attachment in which the links created at a given time t are distributed homogeneously between a new node and the existing nodes selected uniformly. This is achieved by creating links between nodes uniformly distributed in a homogeneous metric space according to a Fermi-Dirac connection probability with inverse temperature β and general time-dependent chemical potential μ (t ) . The chemical potential limits the spatial extent of newly created links. Using a hidden variable framework, we obtain an analytical expression for the degree sequence and show that μ (t ) can be fixed to yield any given degree distributions, including a scale-free degree distribution. Additionally, we find that depending on the order in which nodes appear in the network—its history—the degree-degree correlations can be tuned to be assortative or disassortative. The effect of the geometry on the structure is investigated through the average clustering coefficient 〈c 〉 . In the thermodynamic limit, we identify a phase transition between a random regime where 〈c 〉→0 when β 0 when β >βc .

  15. The Striking Progress of African Americans in Degree Attainments.

    Science.gov (United States)

    Journal of Blacks in Higher Education, 2002

    2002-01-01

    While the number of blacks earning bachelor's and master's degrees has risen significantly since 1985, and the number of black doctoral degrees rose 110 percent, the percentage of all degrees awarded to blacks at all levels is far lower than the black percentage of the U.S. population. Black women earn 65.7 percent of all doctorates awarded to…

  16. Multivariate correlation analysis of eye cyclotorsion degree in corneal refractive surgery

    Directory of Open Access Journals (Sweden)

    Xiao-Guang Niu

    2015-06-01

    Full Text Available AIM: To explore the correlation between eye cyclotorsion degrees and patient's age, gender, diopter and other factors in corneal refractive surgery. METHODS: A total of 762 wavefront-guided LASIK patients with 1524 eyes were retrospectively analyzed from January 2010 to December 2013 in our hospital. Iris recognition was accomplished successfully and eye cyclotorsion degrees were recorded intraoperatively for all the patients. The correlations between eye cyclotorsion degrees and patient's age, gender, different eye, diopter and the dominant eye or not were statistically analyzed. In which correlation analysis was used to analyze the relationship between eye cyclotorsion degrees and age and diopter, while the correlations with gender, different eye and the dominant eye or not were analyzed using t-test.RESULTS: The eye cyclotorsion degrees of patients were 0 to 9.7 degrees with an average of 3.08±2.22 degrees. Amongst the average cyclotorsion of 444 men with 888 eyes were 3.05±2.26 degrees, 318 women with 636 eyes were 3.12±2.15 degrees and there were no significant differences(t=1.905, P=0.168. The average age of all the patients was 22.6±5.4y. No significant correlation was found between cyclotorsion degrees and age(r=-0.012, P=0.748. The mean spherical equivalent was -4.76±1.77 degrees, and there was no significant correlation between the eye cyclotorsion degrees and spherical equivalent(r=0.017, P=0.633. The mean cylinder was -0.60±0.64 degrees of no significant correlation with eye cyclotorsion degrees(r=-0.004, P=0.910. The cyclotorsion of dominant eyes of all the patients was 3.0±2.17 degrees, and the non-dominant eyes were 3.11±2.12 degrees. No significant differences were found(t=-0.521,P=0.603. CONCLUSION: The eye cyclotorsion degrees occurred in LASIK surgery had no correlation with age, gender, different eye, diopter and the dominant eye or not.

  17. Most probable degree distribution at fixed structural entropy

    Indian Academy of Sciences (India)

    Here we derive the most probable degree distribution emerging ... the structural entropy of power-law networks is an increasing function of the expo- .... tition function Z of the network as the sum over all degree distributions, with given energy.

  18. Education evolution: a historical perspective of associate degree nursing.

    Science.gov (United States)

    Orsolini-Hain, Liana; Waters, Verle

    2009-05-01

    Exploring the inception and growth of associate degree nursing education informs our understanding of what led to such explosive growth so that most of the nursing workforce is currently educated at the associate degree level. The success of associate degree nursing programs led to many divisive years in nursing education of differentiation of practice debates that were hardly productive. Work world practices and patient needs are creating pressures on community colleges to join forces with universities to increase the percentage of baccalaureate-educated nurses. Associate degree nursing education continues to evolve to meet the demands of a higher educated nursing workforce.

  19. Astronomy Degree Recipients Initial Employment: Results from the Follow-Up Survey of Degree Recipients, Classes of 2010, 2011 and 2012 Combined. Focus On

    Science.gov (United States)

    Pold, Jack; Mulvey, Patrick

    2015-01-01

    Each fall the Statistical Research Center (SRC) conducts its Survey of Enrollments and Degrees, which asks all degree-granting physics and astronomy departments in the US to provide information concerning the numbers of students they have enrolled and counts of recent degree recipients. In connection with this survey, SRC asks for the names and…

  20. Astronomy Degree Recipients: Initial Employment. Data from the Degree Recipient Follow-Up Survey for the Classes of 2007, 2008 and 2009. Focus On

    Science.gov (United States)

    Mulvey, Patrick; Shindel, Brandon

    2011-01-01

    Each fall the Statistical Research Center conducts its Survey of Enrollments and Degrees, which asks all degree-granting physics and astronomy departments in the US to provide information concerning the numbers of students they have enrolled and counts of recent degree recipients. In connection with this survey, the authors ask for the names and…

  1. Where are the black-hole entropy degrees of freedom?

    International Nuclear Information System (INIS)

    Das, Saurya; Shankaranarayanan, S

    2007-01-01

    Understanding the area proportionality of black-hole entropy (the 'area law') from an underlying fundamental theory has been one of the goals of all models of quantum gravity. A key question that one asks is: where are the degrees of freedom giving rise to black-hole entropy located? Taking the point of view that entanglement between field degrees of freedom inside and outside the horizon can be a source of this entropy, we show that when the field is in its ground state, the degrees of freedom near the horizon contribute most to the entropy, and the area law is obeyed. However, when it is in an excited state, degrees of freedom far from the horizon contribute more significantly, and deviations from the area law are observed. In other words, we demonstrate that horizon degrees of freedom are responsible for the area law

  2. Marketingový mix HC Enegie Karlovy Vary

    OpenAIRE

    Štrobl, Adam

    2016-01-01

    Title: Marketing mix of HC Energie Karlovy Vary Objectives: This thesis is based on a questionnaire responses obtained from HC Energie Karlovy Vary fans. Its objective is focused on evaluation of their opinions on the marketing mix, their subsequent interpretation, and finally even development of recommendations for improvement based on previous analysis. Methods: Two methods are used to analyse the marketing mix. The first method is qualitative participant observation. The second method is a...

  3. Õunpuu Karlovy Varys edukas

    Index Scriptorium Estoniae

    2010-01-01

    45. Karlovy Vary filmifestivali võistlusprogrammis "East of the West" märgiti ära Veiko Õunpuu film "Püha Tõnu kiusamine". Peaauhind läks rumeenlase Cristi Puiu filmile "Aurora". Grand prix´sai Augustĺ Vila film "La mosquitera". Teisi preemiasaajaid

  4. Global Stability of Polytopic Linear Time-Varying Dynamic Systems under Time-Varying Point Delays and Impulsive Controls

    Directory of Open Access Journals (Sweden)

    M. de la Sen

    2010-01-01

    Full Text Available This paper investigates the stability properties of a class of dynamic linear systems possessing several linear time-invariant parameterizations (or configurations which conform a linear time-varying polytopic dynamic system with a finite number of time-varying time-differentiable point delays. The parameterizations may be timevarying and with bounded discontinuities and they can be subject to mixed regular plus impulsive controls within a sequence of time instants of zero measure. The polytopic parameterization for the dynamics associated with each delay is specific, so that (q+1 polytopic parameterizations are considered for a system with q delays being also subject to delay-free dynamics. The considered general dynamic system includes, as particular cases, a wide class of switched linear systems whose individual parameterizations are timeinvariant which are governed by a switching rule. However, the dynamic system under consideration is viewed as much more general since it is time-varying with timevarying delays and the bounded discontinuous changes of active parameterizations are generated by impulsive controls in the dynamics and, at the same time, there is not a prescribed set of candidate potential parameterizations.

  5. Batch and column adsorption of herbicide fluroxypyr on different types of activated carbons from water with varied degrees of hardness and alkalinity.

    Science.gov (United States)

    Pastrana-Martínez, L M; López-Ramón, M V; Fontecha-Cámara, M A; Moreno-Castilla, C

    2010-02-01

    There has been little research into the effects of the water hardness and alkalinity of surface waters on the adsorption of herbicides on activated carbons. The aim of this study was to determine the influence of these water characteristics on fluroxypyr adsorption on different activated carbons. At low fluroxypyr surface concentrations, the amount adsorbed from distilled water was related to the surface hydrophobicity. Surface area of carbons covered by fluroxypyr molecules ranged from 60 to 65%. Variations in fluroxypyr solubility with water hardness and alkalinity showed a salting-in effect. Calcium, magnesium and bicarbonate ions were adsorbed to a varied extent on the activated carbons. The presence of fluroxypyr in solution decreased their adsorption due to a competition effect. K(F) from the Freundlich equation linearly increased with water hardness due to salt-screened electrostatic repulsions between charged fluroxypyr molecules. The amount adsorbed from distilled water was largest at high fluroxypyr solution concentrations, because there was no competition between inorganic ions and fluroxypyr molecules. The column breakthrough volume and the amount adsorbed at breakthrough were smaller in tap versus distilled water. Carbon consumption was lower with activated carbon cloth than with the use of granular activated carbon. (c) 2009 Elsevier Ltd. All rights reserved.

  6. Independence, Odd Girth, and Average Degree

    DEFF Research Database (Denmark)

    Löwenstein, Christian; Pedersen, Anders Sune; Rautenbach, Dieter

    2011-01-01

      We prove several tight lower bounds in terms of the order and the average degree for the independence number of graphs that are connected and/or satisfy some odd girth condition. Our main result is the extension of a lower bound for the independence number of triangle-free graphs of maximum...... degree at most three due to Heckman and Thomas [Discrete Math 233 (2001), 233–237] to arbitrary triangle-free graphs. For connected triangle-free graphs of order n and size m, our result implies the existence of an independent set of order at least (4n−m−1) / 7.  ...

  7. The Effect of Varying Jaw-elevator Muscle Forces on a Finite Element Model of a Human Cranium.

    Science.gov (United States)

    Toro-Ibacache, Viviana; O'Higgins, Paul

    2016-07-01

    Finite element analyses simulating masticatory system loading are increasingly undertaken in primates, hominin fossils and modern humans. Simplifications of models and loadcases are often required given the limits of data and technology. One such area of uncertainty concerns the forces applied to cranial models and their sensitivity to variations in these forces. We assessed the effect of varying force magnitudes among jaw-elevator muscles applied to a finite element model of a human cranium. The model was loaded to simulate incisor and molar bites using different combinations of muscle forces. Symmetric, asymmetric, homogeneous, and heterogeneous muscle activations were simulated by scaling maximal forces. The effects were compared with respect to strain distribution (i.e., modes of deformation) and magnitudes; bite forces and temporomandibular joint (TMJ) reaction forces. Predicted modes of deformation, strain magnitudes and bite forces were directly proportional to total applied muscle force and relatively insensitive to the degree of heterogeneity of muscle activation. However, TMJ reaction forces and mandibular fossa strains decrease and increase on the balancing and working sides according to the degree of asymmetry of loading. These results indicate that when modes, rather than magnitudes, of facial deformation are of interest, errors in applied muscle forces have limited effects. However the degree of asymmetric loading does impact on TMJ reaction forces and mandibular fossa strains. These findings are of particular interest in relation to studies of skeletal and fossil material, where muscle data are not available and estimation of muscle forces from skeletal proxies is prone to error. Anat Rec, 299:828-839, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  8. Mixed-Degree Spherical Simplex-Radial Cubature Kalman Filter

    Directory of Open Access Journals (Sweden)

    Shiyuan Wang

    2017-01-01

    Full Text Available Conventional low degree spherical simplex-radial cubature Kalman filters often generate low filtering accuracy or even diverge for handling highly nonlinear systems. The high-degree Kalman filters can improve filtering accuracy at the cost of increasing computational complexity; nevertheless their stability will be influenced by the negative weights existing in the high-dimensional systems. To efficiently improve filtering accuracy and stability, a novel mixed-degree spherical simplex-radial cubature Kalman filter (MSSRCKF is proposed in this paper. The accuracy analysis shows that the true posterior mean and covariance calculated by the proposed MSSRCKF can agree accurately with the third-order moment and the second-order moment, respectively. Simulation results show that, in comparison with the conventional spherical simplex-radial cubature Kalman filters that are based on the same degrees, the proposed MSSRCKF can perform superior results from the aspects of filtering accuracy and computational complexity.

  9. Decontamination of Petroleum-Contaminated Soils Using The Electrochemical Technique: Remediation Degree and Energy Consumption.

    Science.gov (United States)

    Streche, Constantin; Cocârţă, Diana Mariana; Istrate, Irina-Aura; Badea, Adrian Alexandru

    2018-02-19

    Currently, there are different remediation technologies for contaminated soils, but the selection of the best technology must be not only the treatment efficiency but also the energy consumption (costs) during its application. This paper is focused on assessing energy consumption related to the electrochemical treatment of polluted soil with petroleum hydrocarbons. In the framework of a research project, two types of experiments were conducted using soil that was artificially contaminated with diesel fuel at the same level of contamination. The experimental conditions considered for each experiment were: different amounts of contaminated soils (6 kg and 18 kg, respectively), the same current intensity level (0.25A and 0.5A), three different contamination degrees (1%, 2.5% and 5%) and the same time for application of the electrochemical treatment. The remediation degree concerning the removal of petroleum hydrocarbons from soil increased over time by approximately 20% over 7 days. With regard to energy consumption, the results revealed that with an increase in the quantity of treated soil of approximately three times, the specific energy consumption decreased from 2.94 kWh/kg treated soil to 1.64 kWh/kg treated soil.

  10. Are UK undergraduate Forensic Science degrees fit for purpose?

    Science.gov (United States)

    Welsh, Charles; Hannis, Marc

    2011-09-01

    In October 2009 Skills for Justice published the social research paper 'Fit for purpose?: Research into the provision of Forensic Science degree programmes in UK Higher Education Institutions.' The research engaged employers representing 95% of UK Forensic Science providers and 79% of UK universities offering Forensic Science or Crime Scene degree programmes. In addition to this, the research collected the views of 430 students studying these degrees. In 2008 there were approximately 9000 people working in the Forensic Science sector in the UK. The research found that the numbers of students studying Forensic Science or Crime Scene degrees in the UK have more than doubled since 2002-03, from 2191 in to 5664 in 2007-08. Over the same period there were twice as many females as males studying for these degrees. The research concluded that Forensic Science degree programmes offered by UK universities were of a good quality and they provided the student with a positive learning experience but the content was not relevant for Forensic Science employers. This echoed similar research by the former Government Department for Innovation, Universities and Skills on graduates from wider science, technology, engineering and mathematics degree programmes. The research also found that 75% of students studying Forensic Science or Crime Scene degrees expected to have a career in the Forensic Science sector, meaning that ensuring these courses are relevant for employers is a key challenge for universities. This paper reflects on the original research and discusses the implications in light of recent government policy. Copyright © 2011 Forensic Science Society. Published by Elsevier Ireland Ltd. All rights reserved.

  11. Effect of Reynolds number on flow and mass transfer characteristics of a 90 degree elbow

    Science.gov (United States)

    Fujisawa, Nobuyuki; Ikarashi, Yuya; Yamagata, Takayuki; Taguchi, Syoichi

    2016-11-01

    The flow and mass transfer characteristics of a 90 degree elbow was studied experimentally by using the mass transfer measurement by plaster dissolution method, the surface flow visualization by oil film method and stereo PIV measurement. The experiments are carried out in a water tunnel of a circular pipe of 56mm in diameter with a working fluid of water. The Reynolds number was varied from 30000 to 200000. The experimental result indicated the change of the mass transfer coefficient distribution in the elbow with increasing the Reynolds number. This phenomenon is further examined by the surface flow visualization and measurement of secondary flow pattern in the elbow, and the results showed the suggested change of the secondary flow pattern in the elbow with increasing the Reynolds numbers.

  12. Polymorphism and mesomorphism of oligomeric surfactants: effect of the degree of oligomerization.

    Science.gov (United States)

    Jurašin, D; Pustak, A; Habuš, I; Šmit, I; Filipović-Vinceković, N

    2011-12-06

    A series of cationic oligomeric surfactants (quaternary dodecyldimethylammonium ions with two, three, or four chains connected by an ethylene spacer at the headgroup level, abbreviated as dimer, trimer, and tetramer) were synthesized and characterized. The influence of the degree of oligomerization on their polymorphic and mesomorphic properties was investigated by means of X-ray diffraction, polarizing optical microscopy, thermogravimetry, and differential scanning calorimetry. All compounds display layered arrangements with interdigitated dodecyl chains. The increase in the degree of oligomerization increases the interlayer distance and decreases the ordering in the solid phase; whereas the dimer sample is fully crystalline with well-developed 3D ordering and the trimer and tetramer crystallize as highly ordered crystal smectic phases. The number of thermal phase transitions and sequence of phases are markedly affected by the number of dodecyl chains. Anhydrous samples exhibit polymorphism and thermotropic mesomorphism of the smectic type, with the exception of the tetramer that displays only transitions at higher temperature associated with decomposition and melting. All hydrated compounds form lyotropic mesophases showing reversible phase transitions upon heating and cooling. The sequence of liquid-crystalline phases for the dimer, typical of concentrated ionic surfactant systems, comprises a hexagonal phase at lower temperatures and a smectic phase at higher temperatures. In contrast, the trimer and tetramer reveal textures of the hexagonal phase. © 2011 American Chemical Society

  13. Characteristic of 120 degree C thermoluminescence peak of iceland spar

    International Nuclear Information System (INIS)

    Lu Xinwei; Han Jia

    2006-01-01

    The basic characteristic of 120 degree C thermoluminescence peak of iceland spar was studied. The experimental result indicates the longevity of 120 degree C thermoluminescence peak of iceland spar is about 2 h under 30 degree C. The thermoluminescence peak moves to the high temperature when the heating speed increasing. The intensity of 120 degree C thermoluminescence peak of iceland spar is directly proportional to radiation dose under 15 Gy. (authors)

  14. Ecological Momentary Assessment of Pain, Fatigue, Depressive, and Cognitive Symptoms Reveals Significant Daily Variability in Multiple Sclerosis.

    Science.gov (United States)

    Kratz, Anna L; Murphy, Susan L; Braley, Tiffany J

    2017-11-01

    To describe the daily variability and patterns of pain, fatigue, depressed mood, and cognitive function in persons with multiple sclerosis (MS). Repeated-measures observational study of 7 consecutive days of home monitoring, including ecological momentary assessment (EMA) of symptoms. Multilevel mixed models were used to analyze data. General community. Ambulatory adults (N=107) with MS recruited through the University of Michigan and surrounding community. Not applicable. EMA measures of pain, fatigue, depressed mood, and cognitive function rated on a 0 to 10 scale, collected 5 times a day for 7 days. Cognitive function and depressed mood exhibited more stable within-person patterns than pain and fatigue, which varied considerably within person. All symptoms increased in intensity across the day (all Pfatigue showing the most substantial increase. Notably, this diurnal increase varied by sex and age; women showed a continuous increase from wake to bedtime, whereas fatigue plateaued after 7 pm for men (wake-bed B=1.04, P=.004). For the oldest subgroup, diurnal increases were concentrated to the middle of the day compared with younger subgroups, which showed an earlier onset of fatigue increase and sustained increases until bed time (wake-3 pm B=.04, P=.01; wake-7 pm B=.03, P=.02). Diurnal patterns of cognitive function varied by education; those with advanced college degrees showed a more stable pattern across the day, with significant differences compared with those with bachelor-level degrees in the evening (wake-7 pm B=-.47, P=.02; wake-bed B=-.45, P=.04). Findings suggest that chronic symptoms in MS are not static, even over a short time frame; rather, symptoms-fatigue and pain in particular-vary dynamically across and within days. Incorporation of EMA methods should be considered in the assessment of these chronic MS symptoms to enhance assessment and treatment strategies. Copyright © 2017 American Congress of Rehabilitation Medicine. Published by Elsevier

  15. A wavelet-based evaluation of time-varying long memory of equity markets: A paradigm in crisis

    Science.gov (United States)

    Tan, Pei P.; Chin, Cheong W.; Galagedera, Don U. A.

    2014-09-01

    This study, using wavelet-based method investigates the dynamics of long memory in the returns and volatility of equity markets. In the sample of five developed and five emerging markets we find that the daily return series from January 1988 to June 2013 may be considered as a mix of weak long memory and mean-reverting processes. In the case of volatility in the returns, there is evidence of long memory, which is stronger in emerging markets than in developed markets. We find that although the long memory parameter may vary during crisis periods (1997 Asian financial crisis, 2001 US recession and 2008 subprime crisis) the direction of change may not be consistent across all equity markets. The degree of return predictability is likely to diminish during crisis periods. Robustness of the results is checked with de-trended fluctuation analysis approach.

  16. Comparative Evaluation of Friction Resistance of Titanium, Stainless Steel, Ceramic and Ceramic with Metal Insert Brackets with Varying Dimensions of Stainless Steel Wire: An In vitro Multi-center Study.

    Science.gov (United States)

    Kumar, B Sunil; Miryala, Suresh; Kumar, K Kiran; Shameem, K; Regalla, Ravindra Reddy

    2014-09-01

    The orthodontist seeks an archwire-bracket combination that has both good biocompatibility and low friction. Hence, the aim of this multicenter in vitro study was to evaluate and compare the frictional resistance generated between titanium (Ti), stainless steel (SS), ceramic and ceramic with metal insert (CMI) brackets with SS wires of varying dimensions in a specially designed apparatus. The material used in this study were Ti, SS, Ceramic and CMI with 0.018″ slot manufactured with zero degree tip and -7° torque premolar brackets (3M, Unitek) and SS wires of varying dimensions (0.016″ round, 0.016 × 0.016″ square, 0.016 × 0.022″ rectangular and 0.017 × 0.025″ rectangular) used. The frictional resistance was measured using Instron Universal testing machine (Model no. 4301). The specimen population in each center composed each of 160 brackets and wires. Differences among the all bracket/wire combinations were tested using (one-way) ANOVA, followed by the student Newman Keuls multiple comparisons of means ranking (at P bracket in combination with 0.017 × 0.025″ SS rectangular wire produced significant force levels for an optimum orthodontic movement with least frictional resistance. Ti brackets have least resistance and rectangular wires produced significant force. These can be used to avoid hazards of Nickel. SS brackets revealed higher static frictional force values as the wire dimension increased and showed lower static friction than Ti brackets for all wires except the thicker wire. Our study recommends the preclusion of brackets with rough surface texture (Ti brackets) with SS ligature wire for ligating bracket and archwire are better to reduce friction.

  17. Spatially varying selection shapes life history clines among populations of Drosophila melanogaster from sub-Saharan Africa.

    Science.gov (United States)

    Fabian, D K; Lack, J B; Mathur, V; Schlötterer, C; Schmidt, P S; Pool, J E; Flatt, T

    2015-04-01

    Clines in life history traits, presumably driven by spatially varying selection, are widespread. Major latitudinal clines have been observed, for example, in Drosophila melanogaster, an ancestrally tropical insect from Africa that has colonized temperate habitats on multiple continents. Yet, how geographic factors other than latitude, such as altitude or longitude, affect life history in this species remains poorly understood. Moreover, most previous work has been performed on derived European, American and Australian populations, but whether life history also varies predictably with geography in the ancestral Afro-tropical range has not been investigated systematically. Here, we have examined life history variation among populations of D. melanogaster from sub-Saharan Africa. Viability and reproductive diapause did not vary with geography, but body size increased with altitude, latitude and longitude. Early fecundity covaried positively with altitude and latitude, whereas lifespan showed the opposite trend. Examination of genetic variance-covariance matrices revealed geographic differentiation also in trade-off structure, and QST -FST analysis showed that life history differentiation among populations is likely shaped by selection. Together, our results suggest that geographic and/or climatic factors drive adaptive phenotypic differentiation among ancestral African populations and confirm the widely held notion that latitude and altitude represent parallel gradients. © 2015 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2015 European Society For Evolutionary Biology.

  18. A unique degree program for pre-pharmacy education: An undergraduate degree in pharmaceutical sciences.

    Science.gov (United States)

    Jafari, Mahtab

    2018-02-01

    Within the coming decade, the demand for well-trained pharmacists is expected to only increase, especially with the aging of the United States (US) population. To help fill this growing demand, the University of California, Irvine (UCI) aims to offer a unique pre-pharmacy degree program and has developed a Bachelor of Science (BS) degree in Pharmaceutical Sciences to help achieve this goal. In this commentary, we share our experience with our curriculum and highlight its features in an effort to encourage other institutions to enhance the learning experience of their pre-pharmacy students. The efforts of the UCI Department of Pharmaceutical Sciences has resulted in UCI being consistently ranked as one of the top feeder institutions by the Pharmacy College Application Service (PharmCAS) in recent years. The UCI Pharmaceutical Sciences Bachelor of Science offers a unique pre-pharmacy educational experience in an effort to better prepare undergraduates for the rigors of the doctorate of pharmacy curriculum. Copyright © 2017. Published by Elsevier Inc.

  19. Population equations for degree-heterogenous neural networks

    Science.gov (United States)

    Kähne, M.; Sokolov, I. M.; Rüdiger, S.

    2017-11-01

    We develop a statistical framework for studying recurrent networks with broad distributions of the number of synaptic links per neuron. We treat each group of neurons with equal input degree as one population and derive a system of equations determining the population-averaged firing rates. The derivation rests on an assumption of a large number of neurons and, additionally, an assumption of a large number of synapses per neuron. For the case of binary neurons, analytical solutions can be constructed, which correspond to steps in the activity versus degree space. We apply this theory to networks with degree-correlated topology and show that complex, multi-stable regimes can result for increasing correlations. Our work is motivated by the recent finding of subnetworks of highly active neurons and the fact that these neurons tend to be connected to each other with higher probability.

  20. Linear analysis of degree correlations in complex networks

    Indian Academy of Sciences (India)

    Many real-world networks such as the protein–protein interaction networks and metabolic networks often display nontrivial correlations between degrees of vertices connected by edges. Here, we analyse the statistical methods used usually to describe the degree correlation in the networks, and analytically give linear ...

  1. Bouguer gravity anomaly and isostatic residual gravity maps of the Tonopah 1 degree by 2 degrees Quadrangle, central Nevada

    Science.gov (United States)

    Plouff, Donald

    1992-01-01

    These gravity maps are part of a folio of maps of the Tonopah 1 degree by 2 degrees quadrangle, Nevada, prepared under the Conterminous United States Mineral Assessment Program. Each product of the folio is designated by a different letter symbol, starting with A, in the MF-1877 folio. The quadrangle encompasses an area of about 19,500 km2  in the west central part of Nevada.

  2. Degrees of competency: the relationship between educational qualifications and adult skills across countries

    Directory of Open Access Journals (Sweden)

    Natascha Massing

    2017-02-01

    Full Text Available Abstract Background Educational qualifications and literacy skills are highly related. This is not surprising as it is one aim of educational systems to equip individuals with competencies necessary to take part in society. Because of this relationship educational qualifications are often used as a proxy for “human capital”. However, from a theoretical perspective, there are many reasons why this relationship is not perfect, and to some degree this is due to third variables. Thus, we want to explore the net relationship between educational attainment (harmonized according to the International Standard Classification of Education, ISCED and literacy skills, and how much skills vary within education levels across countries. Methods We use data from 21 countries from the Programme for the International Assessment of Adult Competencies 2012. This paper compares the literacy skills of adults who achieved different levels of educational attainment across countries. Given the high degree of educational differentiation in most countries, we do this using a more differentiated educational attainment variable than what is commonly used.  In our analyses we firstly adjust for factors that are likely to affect access to education and the acquisition of educational qualifications and literacy skills, such as parental education and language and migration background. In a second step, we also take into account factors affecting skill development after initial formal education, such as occupation and skill use at home. Results We firstly find a high degree of heterogeneity of skills across countries for equivalent education categories. Secondly, we find skill similarities for equivalent education categories classified at different broad education levels, sometimes even breaking the hierarchical order of ‘higher education entails higher competencies’. Conclusion We conclude that ISCED levels cannot be taken as a cross-nationally comparable proxy for

  3. Constrained multi-degree reduction with respect to Jacobi norms

    KAUST Repository

    Ait-Haddou, Rachid; Barton, Michael

    2015-01-01

    We show that a weighted least squares approximation of Bézier coefficients with factored Hahn weights provides the best constrained polynomial degree reduction with respect to the Jacobi L2L2-norm. This result affords generalizations to many previous findings in the field of polynomial degree reduction. A solution method to the constrained multi-degree reduction with respect to the Jacobi L2L2-norm is presented.

  4. Constrained multi-degree reduction with respect to Jacobi norms

    KAUST Repository

    Ait-Haddou, Rachid

    2015-12-31

    We show that a weighted least squares approximation of Bézier coefficients with factored Hahn weights provides the best constrained polynomial degree reduction with respect to the Jacobi L2L2-norm. This result affords generalizations to many previous findings in the field of polynomial degree reduction. A solution method to the constrained multi-degree reduction with respect to the Jacobi L2L2-norm is presented.

  5. Boson and fermion degrees of freedom in the orthosymplectic extension of the IVBM: Odd-odd nuclear spectra

    International Nuclear Information System (INIS)

    Ganev, H. G.; Georgieva, A. I.

    2008-01-01

    The dynamical symmetry group Sp(12, R) of the Interacting Vector Boson Model (IVBM) is extended to the orthosymplectic group OSp(2Ω/12, R) in order to incorporate fermion degrees of freedom. The structure of even-even nuclei is used as a core on which the collective excitations of the neighboring odd-mass and odd-odd nuclei are build on. Hence, the spectra of odd-mass and odd-odd nuclei arise as a result of the coupling of the fermion degrees of freedom, specified by the fermion sector SOF (2Ω) to the boson core, whose states belong to an Sp(12, R) irreducible representation. The orthosymplectic dynamical symmetry is applied for the simultaneous description of the spectra of some neighboring nuclei from rare earth region. The theoretical predictions for different low-lying collective bands with positive and negative parity are compared with the experiment. The obtained results reveal the applicability of the model and its boson-fermion extension.

  6. Six-Degree Head-Down Tilt Bed Rest: Forty Years of Development as a Physiological Analog for Weightlessness

    Science.gov (United States)

    Smith, Jeffrey D.; Cromwell, Ronita L.; Kundrot, Craig E.; Charles, John B.

    2011-01-01

    Early on, bed rest was recognized as a method for inducing many of the physiological changes experienced by spaceflight. Head-down tilt (HDT) bed rest was first introduced as an analog for spaceflight by a Soviet team led by Genin and Kakurin. Their study was performed in 1970 (at -4 degrees) and lasted for 30 days; results were reported in the Russian Journal of Space Biology (Kosmicheskaya Biol. 1972; 6(4): 26-28 & 45-109). The goal was to test physiological countermeasures for cosmonauts who would soon begin month-long missions to the Salyut space station. HDT was chosen to produce a similar sensation of blood flow to the head reported by Soyuz cosmonauts. Over the next decade, other tilt angles were studied and comparisons with spaceflight were made, showing that HDT greater than 4 degrees was superior to horizontal bed rest for modeling acute physiological changes observed in space; but, at higher angles, subjects experienced greater discomfort without clearly improving the physiological comparison to spaceflight. A joint study performed by US and Soviet investigators, in 1979, set the goal of standardization of baseline conditions and chose 6-degrees HDT. This effectively established 6-degree HDT bed rest as the internationally-preferred analog for weightlessness and, since 1990, nearly all further studies have been conducted at 6-degrees HDT. A thorough literature review (1970-2010) revealed 534 primary scientific journal articles which reported results from using HDT as a physiological analog for spaceflight. These studies have ranged from as little as 10 minutes to the longest duration of 370 days. Long-term studies lasting four weeks or more have resulted in over 170 primary research articles. Today, the 6-degree HDT model provides a consistent, thoroughly-tested, ground-based analog for spaceflight and allows the proper scientific controls for rigorous testing of physiological countermeasures; however, all models have their strengths and limits. The 6

  7. Integrated energy markets and varying degrees of liberalisation: price links, bundled sales and CHP production exemplified by Northern European experiences

    International Nuclear Information System (INIS)

    Jacobsen, H.K.; Fristrup, P.; Munksgaard, J.

    2006-01-01

    Liberalisation of energy markets has during the last 20 years been gradually introduced in many countries. The liberalisation has led to concerns regarding the markets' state of competition and fears that market power existence can result in less efficiency gains than what is expected from liberalisation. Concerns have also been raised as to whether specific consumer groups will be affected by limited competition in markets. Much of the concern has been concentrated on the electricity markets, but the development of energy sectors with integration of activities within natural gas, electricity and the oil sector creates the need to examine market power aspects across these markets. This paper examines the concentration trends in the Northern European markets for electricity and natural gas, combined with regional district heating aspects, especially with respect to the situation in Denmark. The situation with natural gas companies supplying to both small-scale CHP and to retail heat customers is discussed, for instance, which changes of regulatory regime for domestic heating customers should be considered when the natural gas market is being liberalised? The interlinked nature of the energy markets is described and examples of impacts from one market with limited competition to other markets with seemingly well-functioning competition are given. The specific case of large CHP production facilities with output on the regulated district heating market and the competitive Nordic electricity market is examined. How much of the fluctuations in price experienced in electricity markets should be reflected in the price of heating supplies? To which degree do the heating customers have to bear the burden of low-electricity market prices? Regulation of liberalised markets is discussed focusing on the interaction between one regulated market and the related energy markets that are liberalised. Existing regulation on the markets are compared to a situation where liberalisation

  8. Integrated energy markets and varying degrees of liberalisation: Price links, bundled sales and CHP production exemplified by Northern European experiences

    International Nuclear Information System (INIS)

    Klinge Jacobsen, Henrik; Fristrup, Peter; Munksgaard, Jesper

    2006-01-01

    Liberalisation of energy markets has during the last 20 years been gradually introduced in many countries. The liberalisation has led to concerns regarding the markets' state of competition and fears that market power existence can result in less efficiency gains than what is expected from liberalisation. Concerns have also been raised as to whether specific consumer groups will be affected by limited competition in markets. Much of the concern has been concentrated on the electricity markets, but the development of energy sectors with integration of activities within natural gas, electricity and the oil sector creates the need to examine market power aspects across these markets. This paper examines the concentration trends in the Northern European markets for electricity and natural gas, combined with regional district heating aspects, especially with respect to the situation in Denmark. The situation with natural gas companies supplying to both small-scale CHP and to retail heat customers is discussed, for instance, which changes of regulatory regime for domestic heating customers should be considered when the natural gas market is being liberalised? The interlinked nature of the energy markets is described and examples of impacts from one market with limited competition to other markets with seemingly well-functioning competition are given. The specific case of large CHP production facilities with output on the regulated district heating market and the competitive Nordic electricity market is examined. How much of the fluctuations in price experienced in electricity markets should be reflected in the price of heating supplies? To which degree do the heating customers have to bear the burden of low-electricity market prices? Regulation of liberalised markets is discussed focusing on the interaction between one regulated market and the related energy markets that are liberalised. Existing regulation on the markets are compared to a situation where liberalisation

  9. Assessment of Aliasing Errors in Low-Degree Coefficients Inferred from GPS Data

    Directory of Open Access Journals (Sweden)

    Na Wei

    2016-05-01

    Full Text Available With sparse and uneven site distribution, Global Positioning System (GPS data is just barely able to infer low-degree coefficients in the surface mass field. The unresolved higher-degree coefficients turn out to introduce aliasing errors into the estimates of low-degree coefficients. To reduce the aliasing errors, the optimal truncation degree should be employed. Using surface displacements simulated from loading models, we theoretically prove that the optimal truncation degree should be degree 6–7 for a GPS inversion and degree 20 for combing GPS and Ocean Bottom Pressure (OBP with no additional regularization. The optimal truncation degree should be decreased to degree 4–5 for real GPS data. Additionally, we prove that a Scaled Sensitivity Matrix (SSM approach can be used to quantify the aliasing errors due to any one or any combination of unresolved higher degrees, which is beneficial to identify the major error source from among all the unresolved higher degrees. Results show that the unresolved higher degrees lower than degree 20 are the major error source for global inversion. We also theoretically prove that the SSM approach can be used to mitigate the aliasing errors in a GPS inversion, if the neglected higher degrees are well known from other sources.

  10. Optimistlik Karlovy Vary / Jaan Ruus

    Index Scriptorium Estoniae

    Ruus, Jaan, 1938-2017

    2007-01-01

    42. Karlovy Vary rahvusvahelise filmifestivali auhinnatud filmidest (žürii esimees Peter Bart). Kristallgloobuse sai Islandi-Saksamaa "Katseklaasilinn" (režii Baltasar Kormakur), parimaks režissööriks tunnistati norralane Bard Breien ("Negatiivse mõtlemise kunst"). Austraallase Michael James Rowlandi "Hea õnne teekond" sai žürii eripreemia

  11. Degree of Success? A Review of Delivering BSc Honours Degrees in an FE College

    Science.gov (United States)

    Griffiths, Colin; Lloyd, Mary Golding

    2009-01-01

    Widening participation initiatives led by the government encourage non-traditional students to enrol in higher education courses usually offered through a franchising arrangement between a Higher Education Institution (HEI) and a local Further Education Institution (FEI). The focus has been on the development of foundation degrees with most…

  12. Chapter 3: Crossing Boundaries--Foundation Degrees in England

    Science.gov (United States)

    Longhurst, Derek

    2010-01-01

    This chapter traces the history, purposes, and distinctive features of the foundation degree, a short-cycle higher education qualification introduced in England in 2000-2001 and offered by both universities and further education colleges. The key characteristics of the foundation degree are discussed: employer involvement in curriculum development…

  13. Cross-Evaluation of Degree Programmes in Higher Education

    Science.gov (United States)

    Kettunen, Juha

    2010-01-01

    Purpose: This study seeks to develop and describe the benchmarking approach of enhancement-led evaluation in higher education and to present a cross-evaluation process for degree programmes. Design/methodology/approach: The benchmarking approach produces useful information for the development of degree programmes based on self-evaluation,…

  14. Linear analysis of degree correlations in complex networks

    Indian Academy of Sciences (India)

    2016-11-02

    Nov 2, 2016 ... 4College of Science, Qi Lu University of Technology, Jinan 250353, Shandong, China ... cal methods used usually to describe the degree correlation in the ... Most social networks show assorta- .... a clear but only qualitative description of the degree ... is difficult to give quantitative relation between DCC.

  15. Special Report: Top 100 Degree Producers. Part II.

    Science.gov (United States)

    Black Issues in Higher Education, 1999

    1999-01-01

    Data on the colleges and universities producing the highest numbers of minority master's, doctoral, and first professional degrees in 1996-1997 are presented. Rankings are organized by degree level, ethnic group (African American, Hispanic American, Asian American, Native American), discipline group, and overall graduation rate. Breakouts are also…

  16. Georgia Power Company's college degree program

    International Nuclear Information System (INIS)

    Coggin, C.L.

    1988-01-01

    The purpose of this paper is to describe Georgia Power Company's on-site college degree program for nuclear power plant personnel. In February 1986, the US Nuclear Regulatory Commission issued a policy statement concerning engineering expertise on shift (Generic Letter 86-04), which appeared in Volume 50, Number 208 of the October 28, 1985 Federal Register. One of the options available to nuclear power plant personnel to meet the requirement was the combined senior reactor operator/shift technical adviser position. One of the methods for meeting the option included a bachelor's degree in engineering technology for an accredited institution, including course work in the physical, mathematical, or engineering sciences

  17. Burden of volcanic dust and nuclear debris after injection into the stratosphere at 40 degree to 58 degree N

    International Nuclear Information System (INIS)

    Volz, F.E.

    1975-01-01

    Meridional profiles of turbidity at some periods after the explosion of Katmai volcano in June 1912 at 58degreeN are compared with debris burden from Chinese nuclear tests. Katmai turbidity was previously obtained from solar radiation data, and debris burden was calculated from published mixing ratio data. Turbidity and burden generally peak strongly in arctic latitudes. Only two tests show indications of a bulge at 30degree-45degreeN which probably existed for Katmai dust in spring 1913. The residence time of Katmai dust was found to have been about 1 year, whereas fallout of nuclear debris seems not to have started before the winter following the tests. For September 1912 the total amount of Katmai aerosol is estimated to have been 13 million metric tons. Analogies to predicted meridional distribution of SST pollutants are being mentioned

  18. Time-varying value of electric energy efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Mims, Natalie A.; Eckman, Tom; Goldman, Charles

    2017-06-30

    Electric energy efficiency resources save energy and may reduce peak demand. Historically, quantification of energy efficiency benefits has largely focused on the economic value of energy savings during the first year and lifetime of the installed measures. Due in part to the lack of publicly available research on end-use load shapes (i.e., the hourly or seasonal timing of electricity savings) and energy savings shapes, consideration of the impact of energy efficiency on peak demand reduction (i.e., capacity savings) has been more limited. End-use load research and the hourly valuation of efficiency savings are used for a variety of electricity planning functions, including load forecasting, demand-side management and evaluation, capacity and demand response planning, long-term resource planning, renewable energy integration, assessing potential grid modernization investments, establishing rates and pricing, and customer service. This study reviews existing literature on the time-varying value of energy efficiency savings, provides examples in four geographically diverse locations of how consideration of the time-varying value of efficiency savings impacts the calculation of power system benefits, and identifies future research needs to enhance the consideration of the time-varying value of energy efficiency in cost-effectiveness screening analysis. Findings from this study include: -The time-varying value of individual energy efficiency measures varies across the locations studied because of the physical and operational characteristics of the individual utility system (e.g., summer or winter peaking, load factor, reserve margin) as well as the time periods during which savings from measures occur. -Across the four locations studied, some of the largest capacity benefits from energy efficiency are derived from the deferral of transmission and distribution system infrastructure upgrades. However, the deferred cost of such upgrades also exhibited the greatest range

  19. Experimental evidence for amplitude death induced by a time-varying interaction

    Energy Technology Data Exchange (ETDEWEB)

    Suresh, K. [Centre for Nonlinear Dynamics, School of Physics, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu (India); Shrimali, M.D. [Department of Physics, Central University of Rajasthan, NH-8, Bandar Sindri, Ajmer 305 801 (India); Prasad, Awadhesh [Department of Physics and Astrophysics, University of Delhi, Delhi 110 007 (India); Thamilmaran, K., E-mail: maran.cnld@gmail.com [Centre for Nonlinear Dynamics, School of Physics, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu (India)

    2014-08-01

    In this paper, we study the time-varying interaction in coupled oscillatory systems. For this purpose, we have designed a novel time-varying resistive network using an analog switch and inverter circuits. We have applied this time-varying resistive network to mutually coupled identical Chua's oscillators. When the resistances are varied in time, we find that amplitude death arises in coupled identical oscillators. This has been observed numerically as well as verified through hardware experiments. - Highlights: • We have implemented the time-varying interaction in coupled oscillatory systems. • We have designed a novel time-varying resistive network using an analog switch and inverter circuits. • When the resistances are varied in time, we find that amplitude death arises in coupled identical oscillators.

  20. Brane world cosmologies with varying speed of light

    International Nuclear Information System (INIS)

    Youm, Donam

    2001-02-01

    We study cosmologies in the Randall-Sundrum models, incorporating the possibility of time-varying speed of light and Newton's constant. The cosmologies with varying speed of light (VSL) were proposed by Moffat and by Albrecht and Magueijo as an alternative to inflation for solving the cosmological problems. We consider the case in which the speed of light varies with time after the radion or the scale of the extra dimension has been stabilized. We elaborate on the conditions under which the flatness problem and the cosmological constant problem can be resolved. Particularly, the VSL cosmologies may provide a possible mechanism for bringing the quantum corrections to the fine-tuned brane tensions after the SUSY breaking under control. (author)

  1. Science Majors and Degrees among Asian-American Students: Influences of Race and Sex in "model Minority" Experiences

    Science.gov (United States)

    Meng, Yu; Hanson, Sandra L.

    Both race and sex continue to be factors that stratify entry into science education and occupations in the United States. Asian-Americans (men and women) have experienced considerable success in the sciences and have earned the label of "model minority." The complexities and patterns involved in this success remain elusive. We use several concepts coming out of the status attainment framework and a multicultural gender perspective to explore the way in which race and sex come together to influence choices of science major and degree. Our sample consists of Asian-American and white students in the National Educational Longitudinal Study. Findings suggest that being male and being Asian-American are both associated with higher chances of pursuing majors and degrees in science. The male advantage is greater than the Asian-American advantage. Findings also suggest that race and sex interact in the science decision. For example, race differences (with an Asian-American advantage) in choice of science major are significant for women but not men. Sex differences (with a male advantage) in choice of science major are significant in the white, but not the Asian-American sample. A different set of race and sex patterns is revealed in the science degree models. Processes associated with family socioeconomic status and student characteristics help to explain race and sex patterns. Findings suggest that when Asian-American youths have closer ties to the Asian culture, they are more likely to choose science majors and degrees. Implications for policy, practice, and research in science education are discussed.

  2. Multistability of neural networks with discontinuous non-monotonic piecewise linear activation functions and time-varying delays.

    Science.gov (United States)

    Nie, Xiaobing; Zheng, Wei Xing

    2015-05-01

    This paper is concerned with the problem of coexistence and dynamical behaviors of multiple equilibrium points for neural networks with discontinuous non-monotonic piecewise linear activation functions and time-varying delays. The fixed point theorem and other analytical tools are used to develop certain sufficient conditions that ensure that the n-dimensional discontinuous neural networks with time-varying delays can have at least 5(n) equilibrium points, 3(n) of which are locally stable and the others are unstable. The importance of the derived results is that it reveals that the discontinuous neural networks can have greater storage capacity than the continuous ones. Moreover, different from the existing results on multistability of neural networks with discontinuous activation functions, the 3(n) locally stable equilibrium points obtained in this paper are located in not only saturated regions, but also unsaturated regions, due to the non-monotonic structure of discontinuous activation functions. A numerical simulation study is conducted to illustrate and support the derived theoretical results. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Long-term acoustical observations of the mesopelagic fish Maurolicus muelleri reveal novel and varied vertical migration patterns

    KAUST Repository

    Staby, A

    2011-11-15

    We studied the temporal dynamics in the vertical distribution of Maurolicus muelleri scattering layers (SL) by examining continuous acoustic recordings over a 15 mo period in Masfjorden, Norway, complemented by intermittent sampling campaigns. The data revealed known patterns as normal diel vertical migration (DVM), midnight sinking between dusk and dawn, and periods without migrations, as well as novel behaviours consisting of early morning ascents, reverse diel vertical migrations, and interrupted ascents in the evening. During the first autumn of the study, adult fish modified their normal DVM behaviour by suspending their migration in the evening, yet ascending toward the surface in the later part of the night to reach upper layers during dawn. This behaviour was not observed during the second autumn of the study. By mid- to end of November (1st autumn), adult fish had suspended the nocturnal ascent entirely, and in the subsequent period until the end of January, a fraction of the population rather performed limited reverse migrations, slightly shifting their vertical distribution upwards during the first part of the day. From January to March 2008, fish interrupted their evening ascent at apparently random intervals and returned to deeper waters, instead of completing a full ascent to the surface. Our study underlines the value of long-term recordings, with the results suggesting that M. muelleri has the capability of changing its behaviour in response to ontogeny and internal state (satiation and hunger) as well as to external stimuli.

  4. Biodegradation of petroleum hydrocarbons in seawater at low temperatures (0-5 degrees C) and bacterial communities associated with degradation.

    Science.gov (United States)

    Brakstad, Odd G; Bonaunet, Kristin

    2006-02-01

    In this study biodegradation of hydrocarbons in thin oil films was investigated in seawater at low temperatures, 0 and 5 degrees C. Heterotrophic (HM) or oil-degrading (ODM) microorganisms enriched at the two temperatures showed 16S rRNA sequence similarities to several bacteria of Arctic or Antarctic origin. Biodegradation experiments were conducted with a crude mineral oil immobilized as thin films on hydrophobic Fluortex adsorbents in nutrient-enriched or sterile seawater. Chemical and respirometric analysis of hydrocarbon depletion showed that naphthalene and other small aromatic hydrocarbons (HCs) were primarily biodegraded after dissolution to the water phase, while biodegradation of larger polyaromatic hydrocarbons (PAH) and C(10)-C(36) n-alkanes, including n-hexadecane, was associated primarily with the oil films. Biodegradation of PAH and n-alkanes was significant at both 0 and 5 degrees C, but was decreased for several compounds at the lower temperature. n-Hexadecane biodegradation at the two temperatures was comparable at the end of the experiments, but was delayed at 0 degree C. Investigations of bacterial communities in seawater and on adsorbents by PCR amplification of 16S rRNA gene fragments and DGGE analysis indicated that predominant bacteria in the seawater gradually adhered to the oil-coated adsorbents during biodegradation at both temperatures. Sequence analysis of most DGGE bands aligned to members of the phyla Proteobacteria (Gammaproteobacteria) or Bacteroidetes. Most sequences from experiments at 0 degree C revealed affiliations to members of Arctic or Antarctic consortia, while no such homology was detected for sequences from degradation experiment run at 5 degrees C. In conclusion, marine microbial communities from cold seawater have potentials for oil film HC degradation at temperatures < or =5 degrees C, and psychrotrophic or psychrophilic bacteria may play an important role during oil HC biodegradation in seawater close to freezing

  5. A degree of success? Messages from the new social work degree in England for nurse education.

    Science.gov (United States)

    Moriarty, Jo; Manthorpe, Jill; Stevens, Martin; Hussein, Shereen; Macintyre, Gillian; Orme, Joan; Green Lister, Pam; Sharpe, Endellion; Crisp, Beth

    2010-07-01

    In September 2008 the Nursing and Midwifery Council (NMC) approved plans to change pre-registration nursing education in England to an all-graduate qualification in 2015. In 2001 the Department of Health announced a similar decision for social work qualifying education and the first graduate-only qualifying programmes began in 2003-2004. This article presents findings from a national in-depth evaluation of the social work degree in England and describes ways in which efforts have been made to improve the quality of social workers, raise the status of the profession and link practice and theory as part of the transformation to a degree level qualification. Messages for nurse educators are drawn in the light of the professions' commonalities. Copyright 2009 Elsevier Ltd. All rights reserved.

  6. Phase relations in the metal-rich portions of the phase system Pt-Ir-Fe-S at 1000 degrees C and 1100 degrees C

    DEFF Research Database (Denmark)

    Makovicky, E.; Karup-Møller, Sven

    2000-01-01

    Phase relations in the S-poor portions of the dry condensed Pt-Ir-Fe-S system were determined at 1000 degrees and 1100 degreesC with a particular emphasis on delineation of the solid solubility fields of the Pt-Ir-Fe alloys. At both temperatures, a broad field of gamma (Ir,Fe,Pt) alloy coexists...... with gamma-(Pt,Fe), Pt3Fe and PtFe which dissolve respectively at least 5.1, 29.3 and 24.0 at.% Ir at 1100 degreesC (2.2, 23.6 and less than or equal to 17.2 at.% Ir at 1000 degreesC). Gaps between the nearly Ir-free Pt-Fe alloys gamma (Pt,Fe), Pt3Fe s.s., PtFe s.s. and gamma (Fe,Pt) were estimated as 20......-23 at.%, 40-42 at.% and 54.2-similar to 57 at.% Fe at 1100 degreesC (18-23, 39.5-42.5 and 59-62 at.% Fe at 1000 degreesC). The first gap agrees with data from natural phases by Cabri et ni. (1996). The Fe-rich sulphide melt dissolves only traces of Pt and Ir; Fe1-xS dissolves up to 5.8 at.% Ir at 1100...

  7. Probabilistic relation between In-Degree and PageRank

    NARCIS (Netherlands)

    Litvak, Nelli; Scheinhardt, Willem R.W.; Volkovich, Y.

    2008-01-01

    This paper presents a novel stochastic model that explains the relation between power laws of In-Degree and PageRank. PageRank is a popularity measure designed by Google to rank Web pages. We model the relation between PageRank and In-Degree through a stochastic equation, which is inspired by the

  8. Genetic Diversity of Selected Mangifera Species Revealed by Inter Simple Sequence Repeats Markers

    OpenAIRE

    Ariffin, Zulhairil; Md Sah, Muhammad Shafie; Idris, Salma; Hashim, Nuradni

    2015-01-01

    ISSR markers were employed to reveal genetic diversity and genetic relatedness among 28 Mangifera accessions collected from Yan (Kedah), Bukit Gantang (Perak), Sibuti (Sarawak), and Papar (Sabah). A total of 198 markers were generated using nine anchored primers and one nonanchored primer. Genetic variation among the 28 accessions of Mangifera species including wild relatives, landraces, and clonal varieties is high, with an average degree of polymorphism of 98% and mean Shannon index, H0=7.5...

  9. A Novel Topology Control Approach to Maintain the Node Degree in Dynamic Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Yuanjiang Huang

    2014-03-01

    Full Text Available Topology control is an important technique to improve the connectivity and the reliability of Wireless Sensor Networks (WSNs by means of adjusting the communication range of wireless sensor nodes. In this paper, a novel Fuzzy-logic Topology Control (FTC is proposed to achieve any desired average node degree by adaptively changing communication range, thus improving the network connectivity, which is the main target of FTC. FTC is a fully localized control algorithm, and does not rely on location information of neighbors. Instead of designing membership functions and if-then rules for fuzzy-logic controller, FTC is constructed from the training data set to facilitate the design process. FTC is proved to be accurate, stable and has short settling time. In order to compare it with other representative localized algorithms (NONE, FLSS, k-Neighbor and LTRT, FTC is evaluated through extensive simulations. The simulation results show that: firstly, similar to k-Neighbor algorithm, FTC is the best to achieve the desired average node degree as node density varies; secondly, FTC is comparable to FLSS and k-Neighbor in terms of energy-efficiency, but is better than LTRT and NONE; thirdly, FTC has the lowest average maximum communication range than other algorithms, which indicates that the most energy-consuming node in the network consumes the lowest power.

  10. The propagation of varied timescale perturbations in landscapes

    Science.gov (United States)

    Bingham, N.; Johnson, K. N.; Bookhagen, B.; Chadwick, O.

    2016-12-01

    The classic assumption of steady-state landscapes greatly simplifies models of earth-surface processes. Theoretically, steady-state denotes time independence, but in real landscapes steady-state requires a timescale over which to assume (or document) no change. In the past, poor spatiotemporal resolution of eroding landscapes necessitated that shorter timescale perturbations be ignored in favor of regional formulations of rock uplift = erosion, 105, 6 years. Now, novel techniques and technologies provide an opportunity to define local landscape response to various timescales of perturbations; thus, allowing us to consider multiple steady-states on adjacent watersheds or even along a single watershed. This study seeks to identify the physical propagation of varied timescale perturbations in landscapes in order to provide an updated geomorphic context for interpreting critical zone processes. At our study site - Santa Cruz Island (SCI), CA - perturbations include sea level and climate fluctuations over 105 years coupled with pulses of overgrazing and extreme storm events during the last 200 years. Comprehensive knickpoint location maps and dated marine and fill terraces tighten the spatiotemporal constraints on erosion for SCI. In addition, the island hosts a wide range of lithologies, allowing us to compare lithologic effects on landscape response to perturbations. Our study uses lidar point clouds and high resolution (0.25 and 1 m) digital elevation model analysis to segment landscapes by the degree of their response to perturbations. Landscape response is measured by increases in topographic roughness. We ascertain roughness by analyzing the changes in different terrain attributes on multiple spatial scales: catchment, sub-catchments and individual hillslopes. Terrain attributes utilized include slope, curvature, local relief, flowpath length and contributing catchment area. Statistical analysis of these properties indicates narrower ranges in values for regions

  11. Tracking time-varying coefficient-functions

    DEFF Research Database (Denmark)

    Nielsen, Henrik Aalborg; Nielsen, Torben Skov; Joensen, Alfred K.

    2000-01-01

    is a combination of recursive least squares with exponential forgetting and local polynomial regression. It is argued, that it is appropriate to let the forgetting factor vary with the value of the external signal which is the argument of the coefficient functions. Some of the key properties of the modified method...... are studied by simulation...

  12. Esmaklassiline Karlovy Vary / Jaanus Noormets

    Index Scriptorium Estoniae

    Noormets, Jaanus

    2007-01-01

    Ilmar Raagi mängufilm "Klass" võitis 42. Karlovy Vary rahvusvahelise filmifestivalil kaks auhinda - ametliku kõrvalvõistlusprogrammi "East of the West" eripreemia "Special mention" ja Euroopa väärtfilmikinode keti Europa Cinemas preemia. Ka Asko Kase lühifilmi "Zen läbi prügi linastumisest ning teistest auhinnasaajatest ning osalejatest

  13. Structural determination of ethylene-propylene-diene rubber (EPDM) containing high degree of controlled long-chain branching

    DEFF Research Database (Denmark)

    Mitra, Susanta; Jørgensen, Mikkel; Pedersen, Walther Batsberg

    2009-01-01

    findings and the available theories, an attempt was made to identify the chemical nature and degree of LCB. This study reveals the possibility of detailed characterization of molecular architecture of EPDM containing LCB by comparing with an essentially linear EPDM in light of an existing theory. © 2009...... mass and the presence of LCB. Both rubbers contained 5-ethylidene-2-norbornene (ENB) as diene. Solution cast films of pure EPDM samples were used for different characterization techniques. 1H-NMR, and 13C-NMR were used for assessing the comonomer ratios and LCB. Size exclusion chromatography (SEC...

  14. Degree sequence in message transfer

    Science.gov (United States)

    Yamuna, M.

    2017-11-01

    Message encryption is always an issue in current communication scenario. Methods are being devised using various domains. Graphs satisfy numerous unique properties which can be used for message transfer. In this paper, I propose a message encryption method based on degree sequence of graphs.

  15. Aerospace Technology (Aerospace Engineering Degree)

    OpenAIRE

    Tiseira Izaguirre, Andrés Omar; Blanco Rodríguez, David; Carreres Talens, Marcos; FAJARDO PEÑA, PABLO

    2013-01-01

    Apuntes de la asignatura Tecnología Aeroespacial Tiseira Izaguirre, AO.; Blanco Rodríguez, D.; Carreres Talens, M.; Fajardo Peña, P. (2013). Aerospace Technology (Aerospace Engineering Degree). Editorial Universitat Politècnica de València. http://hdl.handle.net/10251/35263

  16. Anistropically varying conductivity in irreversible electroporation simulations.

    Science.gov (United States)

    Labarbera, Nicholas; Drapaca, Corina

    2017-11-01

    One recent area of cancer research is irreversible electroporation (IRE). Irreversible electroporation is a minimally invasive procedure where needle electrodes are inserted into the body to ablate tumor cells with electricity. The aim of this paper is to propose a mathematical model that incorporates a tissue's conductivity increasing more in the direction of the electrical field as this has been shown to occur in experiments. It was necessary to mathematically derive a valid form of the conductivity tensor such that it is dependent on the electrical field direction and can be easily implemented into numerical software. The derivation of a conductivity tensor that can take arbitrary functions for the conductivity in the directions tangent and normal to the electrical field is the main contribution of this paper. Numerical simulations were performed for isotropic-varying and anisotropic-varying conductivities to evaluate the importance of including the electrical field's direction in the formulation for conductivity. By starting from previously published experimental results, this paper derived a general formulation for an anistropic-varying tensor for implementation into irreversible electroporation modeling software. The anistropic-varying tensor formulation allows the conductivity to take into consideration both electrical field direction and magnitude, as opposed to previous published works that only took into account electrical field magnitude. The anisotropic formulation predicts roughly a five percent decrease in ablation size for the monopolar simulation and approximately a ten percent decrease in ablation size for the bipolar simulations. This is a positive result as previously reported results found the isotropic formulation to overpredict ablation size for both monopolar and bipolar simulations. Furthermore, it was also reported that the isotropic formulation overpredicts the ablation size more for the bipolar case than the monopolar case. Thus, our

  17. Health promotion training in dental and oral health degrees: a scoping review.

    Science.gov (United States)

    Bracksley-O'Grady, Stacey A; Dickson-Swift, Virginia A; Anderson, Karen S; Gussy, Mark G

    2015-05-01

    Dental diseases are a major burden on health; however, they are largely preventable. Dental treatment alone will not eradicate dental disease with a shift to prevention required. Prevention of dental diseases is a role of dental professionals, with most countries having formalized health promotion competencies for dental and oral health graduates. In spite of this, there may be minimal health promotion being undertaken in clinical practice. Therefore, the aim of this study was to conduct a scoping review to identify some published studies on health promotion training in dental and oral health degrees. Key search terms were developed and used to search selected databases, which identified 84 articles. Four articles met the inclusion/exclusion criteria and were included in the review. Of these studies, the type of oral health promotion tasks and instructions received before the tasks varied. However, for all studies the health promotion content was focused on health education. In terms of evaluation of outcomes, only two studies evaluated the health promotion content using student reflections. More good-quality information on health promotions training is needed to inform practice.

  18. Analysis of time-varying psoriasis lesion image patterns

    DEFF Research Database (Denmark)

    Maletti, Gabriela Mariel; Ersbøll, Bjarne Kjær; Nielsen, Allan Aasbjerg

    2004-01-01

    The multivariate alteration detection transform is applied to pairs of within and between time varying registered psoriasis image patterns. Color band contribution to the variates explaining maximal change is analyzed.......The multivariate alteration detection transform is applied to pairs of within and between time varying registered psoriasis image patterns. Color band contribution to the variates explaining maximal change is analyzed....

  19. Specimen loading list for the varying temperature experiment

    International Nuclear Information System (INIS)

    Qualls, A.L.; Sitterson, R.G.

    1998-01-01

    The varying temperature experiment HFIR-RB-13J has been assembled and inserted in the reactor. Approximately 5300 specimens were cleaned, inspected, matched, and loaded into four specimen holders. A listing of each specimen loaded into the steady temperature holder, its position in the capsule, and the identification of the corresponding specimen loaded into the varying temperature holder is presented in this report

  20. Antibacterial activity of some selected plants traditionally used as ...

    African Journals Online (AJOL)

    SAM

    2014-03-26

    Mar 26, 2014 ... K. Womens'College, Kongkhampat,Nambol-795134, Manipur, India. 2Department of Life Science and Bioinformatics, Assam University, Silchar, ... antibacterial activity. The study revealed that all extracts show varied degree of antibacterial activity against the tested bacterial pathogens. The antibacterial ...

  1. [The importance of master's degree and doctorate degree in general surgery].

    Science.gov (United States)

    Montalvo-Javé, Eduardo Esteban; Mendoza-Barrera, Germán Eduardo; Valderrama-Treviño, Alan Isaac; Alcántara-Medina, Stefany; Macías-Huerta, Nain Abraham; Tapia-Jurado, Jesús

    2016-01-01

    The Doctor of Philosophy is the highest academic degree that can be obtained in universities. Graduate Education Program in Medicine in Mexico is divided into 2 major categories: Medical Specialty and Master studies/Doctor of Philosophy. The objective of this study was to demonstrate the importance of master's degrees and Doctor of Philosophy in general surgery. A literature search in PubMed and Medline among others, from 1970 to 2015 with subsequent analysis of the literature reviews found. The physicians who conducted doctoral studies stand out as leaders in research, teaching and academic activities. Dual training with a doctorate medical specialty is a significant predictor for active participation in research projects within the best educational institutions. It is important to study a PhD in the education of doctors specialising in surgery, who show more training in teaching, research and development of academic activities. Currently, although there is a little proportion of students who do not finish the doctoral program, the ones who do are expected to play an important role in the future of medical scientific staff. It has been shown that most doctors with Doctor of Philosophy have wide range of career options. The importance of doctoral studies in the formation of general surgery is due to various reasons; the main one being comprehensively training physician scientists who can develop in clinical, teaching and research. Copyright © 2015 Academia Mexicana de Cirugía A.C. Published by Masson Doyma México S.A. All rights reserved.

  2. The relation between degree-2160 spectral models of Earth's gravitational and topographic potential: a guide on global correlation measures and their dependency on approximation effects

    Science.gov (United States)

    Hirt, Christian; Rexer, Moritz; Claessens, Sten; Rummel, Reiner

    2017-10-01

    Comparisons between high-degree models of the Earth's topographic and gravitational potential may give insight into the quality and resolution of the source data sets, provide feedback on the modelling techniques and help to better understand the gravity field composition. Degree correlations (cross-correlation coefficients) or reduction rates (quantifying the amount of topographic signal contained in the gravitational potential) are indicators used in a number of contemporary studies. However, depending on the modelling techniques and underlying levels of approximation, the correlation at high degrees may vary significantly, as do the conclusions drawn. The present paper addresses this problem by attempting to provide a guide on global correlation measures with particular emphasis on approximation effects and variants of topographic potential modelling. We investigate and discuss the impact of different effects (e.g., truncation of series expansions of the topographic potential, mass compression, ellipsoidal versus spherical approximation, ellipsoidal harmonic coefficient versus spherical harmonic coefficient (SHC) representation) on correlation measures. Our study demonstrates that the correlation coefficients are realistic only when the model's harmonic coefficients of a given degree are largely independent of the coefficients of other degrees, permitting degree-wise evaluations. This is the case, e.g., when both models are represented in terms of SHCs and spherical approximation (i.e. spherical arrangement of field-generating masses). Alternatively, a representation in ellipsoidal harmonics can be combined with ellipsoidal approximation. The usual ellipsoidal approximation level (i.e. ellipsoidal mass arrangement) is shown to bias correlation coefficients when SHCs are used. Importantly, gravity models from the International Centre for Global Earth Models (ICGEM) are inherently based on this approximation level. A transformation is presented that enables a

  3. Predicting the Best Fit: A Comparison of Response Surface Models for Midazolam and Alfentanil Sedation in Procedures With Varying Stimulation.

    Science.gov (United States)

    Liou, Jing-Yang; Ting, Chien-Kun; Mandell, M Susan; Chang, Kuang-Yi; Teng, Wei-Nung; Huang, Yu-Yin; Tsou, Mei-Yung

    2016-08-01

    Selecting an effective dose of sedative drugs in combined upper and lower gastrointestinal endoscopy is complicated by varying degrees of pain stimulation. We tested the ability of 5 response surface models to predict depth of sedation after administration of midazolam and alfentanil in this complex model. The procedure was divided into 3 phases: esophagogastroduodenoscopy (EGD), colonoscopy, and the time interval between the 2 (intersession). The depth of sedation in 33 adult patients was monitored by Observer Assessment of Alertness/Scores. A total of 218 combinations of midazolam and alfentanil effect-site concentrations derived from pharmacokinetic models were used to test 5 response surface models in each of the 3 phases of endoscopy. Model fit was evaluated with objective function value, corrected Akaike Information Criterion (AICc), and Spearman ranked correlation. A model was arbitrarily defined as accurate if the predicted probability is effect-site concentrations tested ranged from 1 to 76 ng/mL and from 5 to 80 ng/mL for midazolam and alfentanil, respectively. Midazolam and alfentanil had synergistic effects in colonoscopy and EGD, but additivity was observed in the intersession group. Adequate prediction rates were 84% to 85% in the intersession group, 84% to 88% during colonoscopy, and 82% to 87% during EGD. The reduced Greco and Fixed alfentanil concentration required for 50% of the patients to achieve targeted response Hierarchy models performed better with comparable predictive strength. The reduced Greco model had the lowest AICc with strong correlation in all 3 phases of endoscopy. Dynamic, rather than fixed, γ and γalf in the Hierarchy model improved model fit. The reduced Greco model had the lowest objective function value and AICc and thus the best fit. This model was reliable with acceptable predictive ability based on adequate clinical correlation. We suggest that this model has practical clinical value for patients undergoing procedures

  4. Effect of degree of polymerization and of temperature on the reactivity of poly(vinyl alcohol) by applying T-for-H exchange reaction

    International Nuclear Information System (INIS)

    Imaizumi, Hiroshi; Imai, Kazunari

    1999-01-01

    In order to reveal the effect of the degree of polymerization and of temperature on the reactivity of functional polymers, the hydrogen-isotope exchange reaction between poly(vinyl alcohol) (PVA) having each degree of polymerization and tritiated water vapor (HTO vapor) was dynamically observed at 35-80 deg C in a gas-solid system. The reason of the observation at 35 deg C is to clarify the possibility of the T-for-H exchange reaction at a temperature near the environment. The degree of polymerization of PVA used in this work was 500, 1000, 2000, 2800, or 3500. Applying the A''-McKay plot method to the data obtained in each observation, the rate constant (k) for each PVA in the reaction was calculated. Moreover, the Arrhenius plot for each PVA was made by using the k values. Comparing the k values and the results obtained previously, the following six matters have been clarified. In the temperature range of 35-80 deg C, the T-for-H exchange reaction between HTO vapor and each PVA occurred, and in this case, the atoms participating in the reaction are the H atoms in the OH groups in PVA and T atoms in HTO vapor. The reactivity of each PVA increases with rising temperature, and decreases with increasing the degree of polymerization. The rate of the decreasing of k with increasing the degree of polymerization changes at near the degree of polymerization of 1000, and the rate is fairly large under the degree of 1000. Under the degree of polymerization of 1000, the reactivity of PVA is more affected by the effect of the degree of polymerization than by the effect of temperature, and the reactivity is large when the degree of polymerization is small. Over the degree of polymerization of 1000, the reactivity of PVA is affected by both the degree of polymerization and temperature, and the reactivity is large when temperature is high. For the T-for-H exchange reaction in a gas-solid system, the reaction form is unchanged in the range of 35-80 deg C, and the reactivity at 35

  5. Brief 74 Nuclear Engineering Enrollments and Degrees Survey, 2014 Data

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2015-03-15

    The 2014 survey includes degrees granted between September 1, 2013 and August 31, 2014, and enrollments for fall 2014. There are three academic programs new to this year's survey. Thirty-five academic programs reported having nuclear engineering programs during 2014, and data were provided by all thirty-five. The enrollments and degrees data include students majoring in nuclear engineering or in an option program equivalent to a major. Two nuclear engineering programs have indicated that health physics option enrollments and degrees are also reported in the health physics enrollments and degrees survey.

  6. Working memory functions in children with different degrees of intellectual disability.

    Science.gov (United States)

    Schuchardt, K; Gebhardt, M; Mäehler, C

    2010-04-01

    In recent years, there has been increased research interest in the functioning of working memory in people with intellectual disabilities. Although studies have repeatedly found these individuals to have weak working memory skills, few investigations have distinguished between different degrees of intellectual disability. This study aims to help close this research gap and, in so doing, to examine whether the deficits observed reflect a developmental lag or a qualitative deviation from normal development. In a 5-group design, the working memory performance of a group of 15-year-olds with mild intellectual disability (IQ 50-69) was compared with that of two groups of children (aged 10 and 15 years) with borderline intellectual disability (IQ 70-84) and with that of two groups of children with average intellectual abilities (IQ 90-115) matched for mental and chronological age (aged 7 and 15 years). All children were administered a comprehensive battery of tests assessing the central executive, the visual-spatial sketchpad, and the phonological loop. The results showed deficits in all three components of working memory, and revealed that these deficits increased with the degree of intellectual disability. The findings indicate that, relative to their mental age peers, children with learning difficulties show structural abnormalities in the phonological store of the phonological loop, but developmental lags in the other two subsystems. Similar patterns of results emerged for both subgroups of children with intellectual disability, indicating that problems with phonological information processing seem to be one of the causes of cognitive impairment in individuals with intellectual disability.

  7. SEIR Model of Rumor Spreading in Online Social Network with Varying Total Population Size

    International Nuclear Information System (INIS)

    Dong Suyalatu; Deng Yan-Bin; Huang Yong-Chang

    2017-01-01

    Based on the infectious disease model with disease latency, this paper proposes a new model for the rumor spreading process in online social network. In this paper what we establish an SEIR rumor spreading model to describe the online social network with varying total number of users and user deactivation rate. We calculate the exact equilibrium points and reproduction number for this model. Furthermore, we perform the rumor spreading process in the online social network with increasing population size based on the original real world Facebook network. The simulation results indicate that the SEIR model of rumor spreading in online social network with changing total number of users can accurately reveal the inherent characteristics of rumor spreading process in online social network . (paper)

  8. Maintaining quality control in a nontraditional nuclear technology degree program

    International Nuclear Information System (INIS)

    DeSain, G.W.

    1989-01-01

    Regents College, created by the Board of Regents of the University of The State on New York in 1971, has been offering, since January 1985, AS and BS degrees in nuclear technology. The impetus for establishing the nuclear technology degrees came from nuclear utility management and had to do with the US Nuclear Regulatory Commission proposed rule regarding degreed operators on shift. There are a variety of ways to earn credits in Regents College degree programs: (1) college courses taken for degree-level credit from regionally accredited colleges; (2) courses sponsored by business, industry, or government that have been evaluated and recommended for credit by the New York National or American Council on Education (ACE's) Program on Noncollegiate Sponsored Instruction (PONSI); (3) military education that has been evaluated by ACE PONSI; (4) approved college-proficiency examinations; and (5) special assessment: an individualized examination of college-level knowledge gained from experience or independent study. Nuclear technology students primarily use college course work, evaluated military education, and proficiency examinations to complete degree programs. However, an increasing number of utilities are having training programs PONSI evaluated, resulting in an increased use of these courses in the nuclear technology degrees. Quality control is a function of several factors described in the paper

  9. Varied line-space gratings and applications

    International Nuclear Information System (INIS)

    McKinney, W.R.

    1991-01-01

    This paper presents a straightforward analytical and numerical method for the design of a specific type of varied line-space grating system. The mathematical development will assume plane or nearly-plane spherical gratings which are illuminated by convergent light, which covers many interesting cases for synchrotron radiation. The gratings discussed will have straight grooves whose spacing varies across the principal plane of the grating. Focal relationships and formulae for the optical grating-pole-to-exist-slit distance and grating radius previously presented by other authors will be derived with a symbolic algebra system. It is intended to provide the optical designer with the tools necessary to design such a system properly. Finally, some possible advantages and disadvantages for application to synchrotron to synchrotron radiation beamlines will be discussed

  10. 360/degree/ digital phase detector with 100-kHz bandwidth

    International Nuclear Information System (INIS)

    Reid, D.W.; Riggin, D.; Fazio, M.V.; Biddle, R.S.; Patton, R.D.; Jackson, H.A.

    1981-01-01

    The general availability of digital circuit components with propagation delay times of a few nanoseconds makes a digital phase detector with good bandwidth feasible. Such a circuit has a distinct advantage over its analog counterpart because of its linearity over a wide range of phase shift. A description is given of a phase detector that is being built at Los Alamos National Laboratory for the Fusion Materials Irradiation Test (FMIT) project. The specifications are 100-kHz bandwidth, linearity of /plus or minus/1/degree/ over /plus or minus/180/degree/ of phase shift, and 0.66/degree/ resolution. To date, the circuit has achieved the bandwidth and resolution. The linearity is approximately /plus or minus/3/degree/ over /plus or minus/180/degree/ phase shift. 3 refs

  11. Biospectroscopy reveals the effect of varying water quality on tadpole tissues of the common frog (Rana temporaria).

    Science.gov (United States)

    Strong, Rebecca J; Halsall, Crispin J; Ferenčík, Martin; Jones, Kevin C; Shore, Richard F; Martin, Francis L

    2016-06-01

    Amphibians are undergoing large population declines in many regions around the world. As environmental pollution from both agricultural and urban sources has been implicated in such declines, there is a need for a biomonitoring approach to study potential impacts on this vulnerable class of organism. This study assessed the use of infrared (IR) spectroscopy as a tool to detect changes in several tissues (liver, muscle, kidney, heart and skin) of late-stage common frog (Rana temporaria) tadpoles collected from ponds with differing water quality. Small differences in spectral signatures were revealed between a rural agricultural pond and an urban pond receiving wastewater and landfill run-off; these were limited to the liver and heart, although large differences in body size were apparent, surprisingly with tadpoles from the urban site larger than those from the rural site. Large differences in liver spectra were found between tadpoles from the pesticide and nutrient impacted pond compared to the rural agricultural pond, particularly in regions associated with lipids. Liver mass and hepatosomatic indices were found to be significantly increased in tadpoles from the site impacted by pesticides and trace organic chemicals, suggestive of exposure to environmental contamination. Significant alterations were also found in muscle tissue between tadpoles from these two ponds in regions associated with glycogen, potentially indicative of a stress response. This study highlights the use of IR spectroscopy, a low-cost, rapid and reagent-free technique in the biomonitoring of a class of organisms susceptible to environmental degradation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Small-scale density variations in the lunar crust revealed by GRAIL

    Science.gov (United States)

    Jansen, J. C.; Andrews-Hanna, J. C.; Li, Y.; Lucey, P. G.; Taylor, G. J.; Goossens, S.; Lemoine, F. G.; Mazarico, E.; Head, J. W.; Milbury, C.; Kiefer, W. S.; Soderblom, J. M.; Zuber, M. T.

    2017-07-01

    Data from the Gravity Recovery and Interior Laboratory (GRAIL) mission have revealed that ∼98% of the power of the gravity signal of the Moon at high spherical harmonic degrees correlates with the topography. The remaining 2% of the signal, which cannot be explained by topography, contains information about density variations within the crust. These high-degree Bouguer gravity anomalies are likely caused by small-scale (10‧s of km) shallow density variations. Here we use gravity inversions to model the small-scale three-dimensional variations in the density of the lunar crust. Inversion results from three non-descript areas yield shallow density variations in the range of 100-200 kg/m3. Three end-member scenarios of variations in porosity, intrusions into the crust, and variations in bulk crustal composition were tested as possible sources of the density variations. We find that the density anomalies can be caused entirely by changes in porosity. Characteristics of density anomalies in the South Pole-Aitken basin also support porosity as a primary source of these variations. Mafic intrusions into the crust could explain many, but not all of the anomalies. Additionally, variations in crustal composition revealed by spectral data could only explain a small fraction of the density anomalies. Nevertheless, all three sources of density variations likely contribute. Collectively, results from this study of GRAIL gravity data, combined with other studies of remote sensing data and lunar samples, show that the lunar crust exhibits variations in density by ± 10% over scales ranging from centimeters to 100‧s of kilometers.

  13. College Teaching as a Profession: The Doctor of Arts Degree.

    Science.gov (United States)

    Dressel, Paul L.

    The history of the Doctor of Arts (D.A.) degree and issues related to its development are briefly traced, and D.A. programs presently available and the success of degree recipients are addressed. Attention is also directed to other types of degree programs that are available, including their advantages and disadvantages, factors involved in…

  14. Wettability modification of Wender lignite by adsorption of dodecyl poly ethoxylated surfactants with different degree of ethoxylation: A molecular dynamics simulation study.

    Science.gov (United States)

    Zhang, Lei; Li, Bao; Xia, Yangchao; Liu, Shengyu

    2017-09-01

    Lignite is an important and useful fossil fuel in the world and the strong hydrophilicity of it limits its applications. Surfactant adsorption on lignite is an effective way to make it hydrophobic. In this work, aiming to examine the effect of the degree of ethoxylation on the adsorption behavior of dodecyl poly ethoxylated surfactants on lignite and the wettability modification of modified lignite by surfactant adsorption, different combined systems formed by surfactants, water and a model surface of Wender lignite have been studied using molecular dynamics simulation. The adsorption configurations vary with the degree of ethoxylation. At the same adsorption amounts, increasing the degree of ethoxylation can make the adsorption layer more compactness and bring stronger adsorption strength. The results of binding energy and its components show that the adsorption of alkyl polyoxyethylene ethers surfactant on lignite is physically adsorbed rather than electrostatically or chemisorbed. Meanwhile, van der Waals interaction plays a dominant role in the adsorption. The addition of surfactant could reduce the possibility of the interaction between water and lignite. Compared to the original lignite, the interaction between them is weakened after surfactant adsorption in water/surfactant/lignite system, thus strengthening the hydrophobicity of lignite. Similar to the adsorption strength, hydrophobicity of modified lignite increases with the increase of the degree of ethoxylation. The lignite surface properties are changed due to surfactant adsorption by analyzing the compositions of interaction energy and the change of hydrogen bonds. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Eesti film võistleb Karlovy Varys

    Index Scriptorium Estoniae

    2008-01-01

    8. juulil esilinastub Karlovy Vary filmifestivalil Rene Vilbre noortefilm "Mina olin siin", mille aluseks on Sass Henno romaan "Mina olin siin. Esimene arest", stsenaariumi kirjutas Ilmar Raag. Film võistleb võistlusprogrammis "East of the West"

  16. Temperature-size responses match latitudinal-size clines in arthropods, revealing critical differences between aquatic and terrestrial species

    DEFF Research Database (Denmark)

    Horne, C.R.; Hirst, Andrew G.; Atkinson, D.

    2015-01-01

    of these gradients to date, and find that their direction and magnitude co-vary among 12 arthropod orders (r2 = 0.72). Body size in aquatic species generally reduces with both warming and decreasing latitude, whereas terrestrial species have much reduced and even opposite gradients. These patterns support...... the prediction that oxygen limitation is a major controlling factor in water, but not in air. Furthermore, voltinism explains much of the variation in T-S and L-S patterns in terrestrial but not aquatic species. While body size decreases with warming and with decreasing latitude in multivoltine terrestrial......Two major intraspecific patterns of adult size variation are plastic temperature-size (T-S) responses and latitude-size (L-S) clines. Yet, the degree to which these co-vary and share explanatory mechanisms has not been systematically evaluated. We present the largest quantitative comparison...

  17. Effective degrees of freedom of a random walk on a fractal

    Science.gov (United States)

    Balankin, Alexander S.

    2015-12-01

    We argue that a non-Markovian random walk on a fractal can be treated as a Markovian process in a fractional dimensional space with a suitable metric. This allows us to define the fractional dimensional space allied to the fractal as the ν -dimensional space Fν equipped with the metric induced by the fractal topology. The relation between the number of effective spatial degrees of freedom of walkers on the fractal (ν ) and fractal dimensionalities is deduced. The intrinsic time of random walk in Fν is inferred. The Laplacian operator in Fν is constructed. This allows us to map physical problems on fractals into the corresponding problems in Fν. In this way, essential features of physics on fractals are revealed. Particularly, subdiffusion on path-connected fractals is elucidated. The Coulomb potential of a point charge on a fractal embedded in the Euclidean space is derived. Intriguing attributes of some types of fractals are highlighted.

  18. Cinema audiences reproducibly vary the chemical composition of air during films, by broadcasting scene specific emissions on breath.

    Science.gov (United States)

    Williams, Jonathan; Stönner, Christof; Wicker, Jörg; Krauter, Nicolas; Derstroff, Bettina; Bourtsoukidis, Efstratios; Klüpfel, Thomas; Kramer, Stefan

    2016-05-10

    Human beings continuously emit chemicals into the air by breath and through the skin. In order to determine whether these emissions vary predictably in response to audiovisual stimuli, we have continuously monitored carbon dioxide and over one hundred volatile organic compounds in a cinema. It was found that many airborne chemicals in cinema air varied distinctively and reproducibly with time for a particular film, even in different screenings to different audiences. Application of scene labels and advanced data mining methods revealed that specific film events, namely "suspense" or "comedy" caused audiences to change their emission of specific chemicals. These event-type synchronous, broadcasted human chemosignals open the possibility for objective and non-invasive assessment of a human group response to stimuli by continuous measurement of chemicals in air. Such methods can be applied to research fields such as psychology and biology, and be valuable to industries such as film making and advertising.

  19. Cinema audiences reproducibly vary the chemical composition of air during films, by broadcasting scene specific emissions on breath

    Science.gov (United States)

    Williams, Jonathan; Stönner, Christof; Wicker, Jörg; Krauter, Nicolas; Derstroff, Bettina; Bourtsoukidis, Efstratios; Klüpfel, Thomas; Kramer, Stefan

    2016-05-01

    Human beings continuously emit chemicals into the air by breath and through the skin. In order to determine whether these emissions vary predictably in response to audiovisual stimuli, we have continuously monitored carbon dioxide and over one hundred volatile organic compounds in a cinema. It was found that many airborne chemicals in cinema air varied distinctively and reproducibly with time for a particular film, even in different screenings to different audiences. Application of scene labels and advanced data mining methods revealed that specific film events, namely “suspense” or “comedy” caused audiences to change their emission of specific chemicals. These event-type synchronous, broadcasted human chemosignals open the possibility for objective and non-invasive assessment of a human group response to stimuli by continuous measurement of chemicals in air. Such methods can be applied to research fields such as psychology and biology, and be valuable to industries such as film making and advertising.

  20. Entropy Rate of Time-Varying Wireless Networks

    DEFF Research Database (Denmark)

    Cika, Arta; Badiu, Mihai Alin; Coon, Justin P.

    2018-01-01

    In this paper, we present a detailed framework to analyze the evolution of the random topology of a time-varying wireless network via the information theoretic notion of entropy rate. We consider a propagation channel varying over time with random node positions in a closed space and Rayleigh...... fading affecting the connections between nodes. The existence of an edge between two nodes at given locations is modeled by a Markov chain, enabling memory effects in network dynamics. We then derive a lower and an upper bound on the entropy rate of the spatiotemporal network. The entropy rate measures...

  1. Master's degree in nuclear engineering by videotaped courses

    International Nuclear Information System (INIS)

    Corradini, M.L.; Vogelsang, W.F.

    1991-01-01

    In 1986, a group of northern midwest utilities met with faculty from the nuclear engineering department at the University of Wisconsin (UW) to discuss the possibility of offering graduate courses by videotape for academic credit and earning a master's degree. Four years later, two utility employees from Northern States Power (NSP) and Wisconsin Electric Power Companies (WEPCO) graduated from the University of Wisconsin with master's degrees earned entirely by taking videotape graduate courses at their individual nuclear power plant sites. Within these 4 years, more than a dozen videotaped graduate courses were developed by the faculty of the department in a formalized master's degree program in nuclear engineering and engineering physics. This paper outlines the program's development and its current features

  2. Maiorana-McFarland class: Degree optimization and algebraic properties

    DEFF Research Database (Denmark)

    Pasalic, Enes

    2006-01-01

    degree of functions in the extended Maiorana-McFarland (MM) class (nonlinear resilient functions F : GF (2)(n) -> GF (2)(m) derived from linear codes). We also show that in the Boolean case, the same subclass seems not to have an optimized algebraic immunity, hence not providing a maximum resistance......In this paper, we consider a subclass of the Maiorana-McFarland class used in the design of resilient nonlinear Boolean functions. We show that these functions allow a simple modification so that resilient Boolean functions of maximum algebraic degree may be generated instead of suboptimized degree...... in the original class. Preserving a high-nonlinearity value immanent to the original construction method, together with the degree optimization gives in many cases functions with cryptographic properties superior to all previously known construction methods. This approach is then used to increase the algebraic...

  3. Solution to the monoenergetic time-dependent neutron transport equation with a time-varying source

    International Nuclear Information System (INIS)

    Ganapol, B.D.

    1986-01-01

    Even though fundamental time-dependent neutron transport problems have existed since the inception of neutron transport theory, it has only been recently that a reliable numerical solution to one of the basic problems has been obtained. Experience in generating numerical solutions to time-dependent transport equations has indicated that the multiple collision formulation is the most versatile numerical technique for model problems. The formulation coupled with a moment reconstruction of each collided flux component has led to benchmark-quality (four- to five-digit accuracy) numerical evaluation of the neutron flux in plane infinite geometry for any degree of scattering anisotropy and for both pulsed isotropic and beam sources. As will be shown in this presentation, this solution can serve as a Green's function, thus extending the previous results to more complicated source situations. Here we will be concerned with a time-varying source at the center of an infinite medium. If accurate, such solutions have both pedagogical and practical uses as benchmarks against which other more approximate solutions designed for a wider class of problems can be compared

  4. Multivariate time-varying volatility modeling using probabilistic fuzzy systems

    NARCIS (Netherlands)

    Basturk, N.; Almeida, R.J.; Golan, R.; Kaymak, U.

    2016-01-01

    Methods to accurately analyze financial risk have drawn considerable attention in financial institutions. One difficulty in financial risk analysis is the fact that banks and other financial institutions invest in several assets which show time-varying volatilities and hence time-varying financial

  5. Degree of Acetylization Chitosan Gonggong Snail Shells

    Science.gov (United States)

    Horiza, H.; Iskandar, I.; Aldo, N.

    2018-04-01

    Chitosan is a polysaccharide obtained from the deacetylation of chitin, which is generally derived from crustacean animal waste and animal skins other sea. One marine animals that have compounds that can be processed chitin chitosan is derived from the snail Gonggong marine waters of Riau Islands province. The purpose of this study was to determine the degree of chitosan from the shells of snails asetilisasi Gonggong. This research is an experimental research laboratory. The results of this study indicate that the degree of chitosan shell snail deasetilisasi Gonggong is 70.27%.

  6. Effects of degree correlation on scale-free gradient networks

    International Nuclear Information System (INIS)

    Pan Guijun; Yan Xiaoqing; Ma Weichuan; Luo Yihui; Huang Zhongbing

    2010-01-01

    We have studied the effects of degree correlation on congestion pressure in scale-free gradient networks. It is observed that the jamming coefficient J is insensitive to the degree correlation coefficient r for assortative and strongly disassortative scale-free networks, and J markedly decreases with an increase in r for weakly disassortative scale-free networks. We have also investigated the effects of degree correlation on the topology structure of scale-free gradient networks, and discussed the relation between the topology structure properties and transport efficiency of gradient networks.

  7. 1-Colored Archetypal Permutations and Strings of Degree n

    Directory of Open Access Journals (Sweden)

    Gheorghe Eduard Tara

    2012-10-01

    Full Text Available New notions related to permutations are introduced here. We present the string of a 1-colored permutation as a closed planar curve, the fundamental 1-colored permutation as an equivalence class related to the equivalence in strings of the 1-colored permutations. We give formulas for the number of the 1-colored archetypal permutations of degree n. We establish an algorithm to identify the 1- colored archetypal permutations of degree n and we present the atlas of the 1-colored archetypal strings of degree n, n ≤ 7, based on this algorithm.

  8. The degree of integration of non-dispensing pharmacists in primary care practice and the impact on health outcomes: A systematic review.

    Science.gov (United States)

    Hazen, Ankie C M; de Bont, Antoinette A; Boelman, Lia; Zwart, Dorien L M; de Gier, Johan J; de Wit, Niek J; Bouvy, Marcel L

    2018-03-01

    A non-dispensing pharmacist conducts clinical pharmacy services aimed at optimizing patients individual pharmacotherapy. Embedding a non-dispensing pharmacist in primary care practice enables collaboration, probably enhancing patient care. The degree of integration of non-dispensing pharmacists into multidisciplinary health care teams varies strongly between settings. The degree of integration may be a determinant for its success. This study investigates how the degree of integration of a non-dispensing pharmacist impacts medication related health outcomes in primary care. In this literature review we searched two electronic databases and the reference list of published literature reviews for studies about clinical pharmacy services performed by non-dispensing pharmacists physically co-located in primary care practice. We assessed the degree of integration via key dimensions of integration based on the conceptual framework of Walshe and Smith. We included English language studies of any design that had a control group or baseline comparison published from 1966 to June 2016. Descriptive statistics were used to correlate the degree of integration to health outcomes. The analysis was stratified for disease-specific and patient-centered clinical pharmacy services. Eighty-nine health outcomes in 60 comparative studies contributed to the analysis. The accumulated evidence from these studies shows no impact of the degree of integration of non-dispensing pharmacists on health outcomes. For disease specific clinical pharmacy services the percentage of improved health outcomes for none, partial and fully integrated NDPs is respectively 75%, 63% and 59%. For patient-centered clinical pharmacy services the percentage of improved health outcomes for none, partial and fully integrated NDPs is respectively 55%, 57% and 70%. Full integration adds value to patient-centered clinical pharmacy services, but not to disease-specific clinical pharmacy services. To obtain maximum benefits

  9. Time-Varying Transition Probability Matrix Estimation and Its Application to Brand Share Analysis.

    Directory of Open Access Journals (Sweden)

    Tomoaki Chiba

    Full Text Available In a product market or stock market, different products or stocks compete for the same consumers or purchasers. We propose a method to estimate the time-varying transition matrix of the product share using a multivariate time series of the product share. The method is based on the assumption that each of the observed time series of shares is a stationary distribution of the underlying Markov processes characterized by transition probability matrices. We estimate transition probability matrices for every observation under natural assumptions. We demonstrate, on a real-world dataset of the share of automobiles, that the proposed method can find intrinsic transition of shares. The resulting transition matrices reveal interesting phenomena, for example, the change in flows between TOYOTA group and GM group for the fiscal year where TOYOTA group's sales beat GM's sales, which is a reasonable scenario.

  10. Time-Varying Transition Probability Matrix Estimation and Its Application to Brand Share Analysis.

    Science.gov (United States)

    Chiba, Tomoaki; Hino, Hideitsu; Akaho, Shotaro; Murata, Noboru

    2017-01-01

    In a product market or stock market, different products or stocks compete for the same consumers or purchasers. We propose a method to estimate the time-varying transition matrix of the product share using a multivariate time series of the product share. The method is based on the assumption that each of the observed time series of shares is a stationary distribution of the underlying Markov processes characterized by transition probability matrices. We estimate transition probability matrices for every observation under natural assumptions. We demonstrate, on a real-world dataset of the share of automobiles, that the proposed method can find intrinsic transition of shares. The resulting transition matrices reveal interesting phenomena, for example, the change in flows between TOYOTA group and GM group for the fiscal year where TOYOTA group's sales beat GM's sales, which is a reasonable scenario.

  11. The effect of curing units and methods on degree of conversion of two types of composite resins

    Directory of Open Access Journals (Sweden)

    Hasani Tabatabaei M

    2007-06-01

    Full Text Available Background and Aim: Halogen lamp is the commonly used light source for composite photo polymerization. Recently, high power halogen lamps, LED and plasma arc are introduced for improving the polymerization. The aim of this study was to investigate the effect of conventional and high power halogen lamps and LED light curing unit on degree of conversion of two different composite resins.Materials and Methods: In this in vitro experimental study two halogen units (Coltolux 50 with the intensity of  330 mW/cm2 and Optilux 501 with two different operating modes of standard with the intensity of 820 mW/cm2 and Ramp with the intentsiy of 100-1030mW/cm2 and one LED light curing unit (620 mW/cm2 were used. The composites were hybrid (Tetric ceram and nanofilled (Filteke supreme. Each materials/curing method contained three samples and degree of conversion (DC was measured with FTIR. Data were analyzed statistically with one way and two way ANOVA, Tukey HSD. P<0.05 was considered as the limit of significance.Results: Tetric ceram revealed higher DCthan Supreme. Tetric ceram showed a significant decrease in DC when Coltolux 50 was used in comparison to LED and Optilux 501. The latters did not show significant effect on DC of this material. DC of Supreme polymerized with various curing modes was not significantly different.Conclusion: Based on the results of this study, degree of conversion in hybrid composites was higher than nanofilled. In comparison with conventional halogen lamp (Coltolux 50, high intensity halogen lamps and LED unit significantly lead to higher degree of conversion in hybrid composites.

  12. The 360-degree evaluation model: A method for assessing competency in graduate nursing students. A pilot research study.

    Science.gov (United States)

    Cormack, Carrie L; Jensen, Elizabeth; Durham, Catherine O; Smith, Gigi; Dumas, Bonnie

    2018-05-01

    The 360 Degree Evaluation Model is one means to provide a comprehensive view of clinical competency and readiness for progression in an online nursing program. This pilot project aimed to evaluate the effectiveness of implementing a 360 Degree Evaluation of clinical competency of graduate advanced practice nursing students. The 360 Degree Evaluation, adapted from corporate industry, encompasses assessment of student knowledge, skills, behaviors and attitudes and validates student's progression from novice to competent. Cohort of advanced practice nursing students in four progressive clinical semesters. Graduate advanced practice nursing students (N = 54). Descriptive statistics and Jonckheere's Trend Test were used to evaluate OSCE's scores from graded rubric, standardized patient survey scores, student reflection and preceptor evaluation. We identified all students passed the four OSCEs during a first attempt or second attempt. Scaffolding OSCE's over time allowed faculty to identify cohort weakness and create subsequent learning opportunities. Standardized patients' evaluation of the students' performance in the domains of knowledge, skills and attitudes, showed high scores of 96% in all OSCEs. Students' self-reflection comments were a mix of strengths and weaknesses in their self-evaluation, demonstrating themes as students progressed. Preceptor evaluation scores revealed the largest increase in knowledge and learning skills (NONPF domain 1), from an aggregate average of 90% in the first clinical course, to an average of 95%. The 360 Degree Evaluation Model provided a comprehensive evaluation of the student and critical information for the faculty ensuring individual student and cohort data and ability to analyze cohort themes. Copyright © 2018 Elsevier Ltd. All rights reserved.

  13. Physiological Perturbation Reveals Modularity of Eyespot Development in the Painted Lady Butterfly, Vanessa cardui

    Science.gov (United States)

    Rhen, Turk; Simmons, Rebecca B.

    2016-01-01

    Butterfly eyespots are complex morphological traits that can vary in size, shape and color composition even on the same wing surface. Homology among eyespots suggests they share a common developmental basis and function as an integrated unit in response to selection. Despite strong evidence of genetic integration, eyespots can also exhibit modularity or plasticity, indicating an underlying flexibility in pattern development. The extent to which particular eyespots or eyespot color elements exhibit modularity or integration is poorly understood, particularly following exposure to novel conditions. We used perturbation experiments to explore phenotypic correlations among different eyespots and their color elements on the ventral hindwing of V. cardui. Specifically, we identified which eyespots and eyespot features are most sensitive to perturbation by heat shock and injection of heparin—a cold shock mimic. For both treatments, the two central eyespots (3 + 4) were most affected by the experimental perturbations, whereas the outer eyespot border was more resistant to modification than the interior color elements. Overall, the individual color elements displayed a similar response to heat shock across all eyespots, but varied in their response to each other. Graphical modeling also revealed that although eyespots differ morphologically, regulation of eyespot size and colored elements appear to be largely integrated across the wing. Patterns of integration, however, were disrupted following heat shock, revealing that the strength of integration varies across the wing and is strongest between the two central eyespots. These findings support previous observations that document coupling between eyespots 3 + 4 in other nymphalid butterflies. PMID:27560365

  14. Method of measuring the degree of fluid pollution

    International Nuclear Information System (INIS)

    Mortensen, A.; Hammer, E.A.

    1995-01-01

    The invention relates to an method and device for measuring the degree of pollution from particulates in fluids. The device consists of an emitter sending out green and red light in succession through the fluid to a light recorder. The recorder itself includes a unit designed for comparing the measured intensity of light with the values of known pollution degree in fluids. 2 figs

  15. Explanation of the degree of Divine Knowledge in the degree of Decrees of fate in Molla Sadra and Allama Tabatabai's views

    Directory of Open Access Journals (Sweden)

    Ali Reza Khwajegir

    the degrees of Divine knowledge that is Divine Decrees of fate, and in the higher phase it ends to Divine intrinsic knowledge. On the other hand, the causal system of the universe and attributing that to its complete cause which is the origin of necessity and creation of the universe is also called objective Decrees of fate. Therefore, the Divine Decrees of fate is the indicative of attributing the whole universe to God in two degrees of scientific and objective. So, detailed analysis and explanation of Divine Decrees of fate should be based on both, Divine knowledge in one side, and necessity of the universe on the other side, because Divine Decrees of fate explains both of them, and paying attention to one of them and neglecting the other, does not reveal to us the fact of Divine Decrees of fate. Molla Sadra thinks the essential Decrees of fate is out of the universe, in the degree of the essence of god, but the actual Decrees of fate is in the universe and since, these scientific forms do not have no existential respect and real-possible dimensions, are not the components of the universe. Therefore, they are eternal old and immortal by divine survival and since, do not have any nature, also do not have any possibility including essential or potential or natural. In the analysis of this view of Molla Sadra, Allama Tabatabai believes that the definition of the Decrees of fate in Molla sara's view, should be attributed to that necessary knowledge of god which is not apart from it, because otherwise, if these forms are needed for essence and out of it, therefore, they will be a part of the univers, and no more they are eternal Old as he has stated. So, in Allama's view, Sadr al-Mote'allehin has considered Decrees of fate restricted to essential Decrees of fate and neglected the actual Decrees of fate. While in the view of Allama, the Truth of the concept of Decrees of fate which is necessitating and fixing on one of the two degrees of knowledge that is essential and

  16. Explanation of the degree of Divine Knowledge in the degree of Decrees of fate in Molla Sadra and Allama Tabatabai's views

    Directory of Open Access Journals (Sweden)

    Alireza Khajegir

    2013-08-01

    one of the degrees of Divine knowledge that is Divine Decrees of fate, and in the higher phase it ends to Divine intrinsic knowledge. On the other hand, the causal system of the universe and attributing that to its complete cause which is the origin of necessity and creation of the universe is also called objective Decrees of fate. Therefore, the Divine Decrees of fate is the indicative of attributing the whole universe to God in two degrees of scientific and objective. So, detailed analysis and explanation of Divine Decrees of fate should be based on both, Divine knowledge in one side, and necessity of the universe on the other side, because Divine Decrees of fate explains both of them, and paying attention to one of them and neglecting the other, does not reveal to us the fact of Divine Decrees of fate.    Molla Sadra thinks the essential Decrees of fate is out of the universe, in the degree of the essence of god, but the actual Decrees of fate is in the universe and since, these scientific forms do not have no existential respect and real-possible dimensions, are not the components of the universe. Therefore, they are eternal old and immortal by divine survival and since, do not have any nature, also do not have any possibility including essential or potential or natural. In the analysis of this view of Molla Sadra, Allama Tabatabai believes that the definition of the Decrees of fate in Molla sara's view, should be attributed to that necessary knowledge of god which is not apart from it, because otherwise, if these forms are needed for essence and out of it, therefore, they will be a part of the univers, and no more they are eternal Old as he has stated. So, in Allama's view, Sadr al-Mote'allehin has considered Decrees of fate restricted to essential Decrees of fate and neglected the actual Decrees of fate. While in the view of Allama, the Truth of the concept of Decrees of fate which is necessitating and fixing on one of the two degrees of knowledge that is

  17. Low cell pH depresses peak power in rat skeletal muscle fibres at both 30 degrees C and 15 degrees C: implications for muscle fatigue.

    Science.gov (United States)

    Knuth, S T; Dave, H; Peters, J R; Fitts, R H

    2006-09-15

    Historically, an increase in intracellular H(+) (decrease in cell pH) was thought to contribute to muscle fatigue by direct inhibition of the cross-bridge leading to a reduction in velocity and force. More recently, due to the observation that the effects were less at temperatures closer to those observed in vivo, the importance of H(+) as a fatigue agent has been questioned. The purpose of this work was to re-evaluate the role of H(+) in muscle fatigue by studying the effect of low pH (6.2) on force, velocity and peak power in rat fast- and slow-twitch muscle fibres at 15 degrees C and 30 degrees C. Skinned fast type IIa and slow type I fibres were prepared from the gastrocnemius and soleus, respectively, mounted between a force transducer and position motor, and studied at 15 degrees C and 30 degrees C and pH 7.0 and 6.2, and fibre force (P(0)), unloaded shortening velocity (V(0)), force-velocity, and force-power relationships determined. Consistent with previous observations, low pH depressed the P(0) of both fast and slow fibres, less at 30 degrees C (4-12%) than at 15 degrees C (30%). However, the low pH-induced depressions in slow type I fibre V(0) and peak power were both significantly greater at 30 degrees C (25% versus 9% for V(0) and 34% versus 17% for peak power). For the fast type IIa fibre type, the inhibitory effect of low pH on V(0) was unaltered by temperature, while for peak power the inhibition was reduced at 30 degrees C (37% versus 18%). The curvature of the force-velocity relationship was temperature sensitive, and showed a higher a/P(0) ratio (less curvature) at 30 degrees C. Importantly, at 30 degrees C low pH significantly depressed the ratio of the slow type I fibre, leading to less force and velocity at peak power. These data demonstrate that the direct effect of low pH on peak power in both slow- and fast-twitch fibres at near-in vivo temperatures (30 degrees C) is greater than would be predicted based on changes in P(0), and that the

  18. Correlation between physics A-levels/A-levels and degree performance

    Science.gov (United States)

    Chadwick, Roy

    1985-09-01

    The author presents an analysis of 178 students who left Solihull Sixth form College between 1975 and 1981 to do a degree in physics (approximately one third) or engineering (approximately two thirds) at university or polytechnic. The first table is an analysis of physics A-level grade and degree performance; the second table an analysis of the points total for physics A-level plus maths A-level (five for A, four for B, etc.), against degree performances, and the final table an analysis of the points total for physics A-level plus maths A-level plus third A-level (again five for A, four for B, etc.), against degree performance.

  19. On Effective Degrees of Freedom in the Early Universe

    Directory of Open Access Journals (Sweden)

    Lars Husdal

    2016-12-01

    Full Text Available We explore the effective degrees of freedom in the early Universe, from before the electroweak scale at a few femtoseconds after the Big Bang until the last positrons disappeared a few minutes later. We look at the established concepts of effective degrees of freedom for energy density, pressure, and entropy density, and introduce effective degrees of freedom for number density as well. We discuss what happens with particle species as their temperature cools down from relativistic to semi- and non-relativistic temperatures, and then annihilates completely. This will affect the pressure and the entropy per particle. We also look at the transition from a quark-gluon plasma to a hadron gas. Using a list a known hadrons, we use a “cross-over” temperature of 214 MeV, where the effective degrees of freedom for a quark-gluon plasma equals that of a hadron gas.

  20. Genetic polymorphisms in varied environments.

    Science.gov (United States)

    Powell, J R

    1971-12-03

    Thirteen experimenital populationis of Drosophila willistoni were maintained in cages, in some of which the environments were relatively constant and in others varied. After 45 weeks, the populations were assayed by gel electrophoresis for polymorphisms at 22 protein loci. The average heterozygosity per individual and the average unmber of alleles per locus were higher in populations maintained in heterogeneous environments than in populations in more constant enviroments.