China's S&T Emergence: A Proposal for U.S. DOD-China Collaboration in Fundamental Research

National Research Council Canada - National Science Library

Berry, William; Loeb, Cheryl

2008-01-01

.... Recent visits to top Chinese academic institutions with strong S&T research programs demonstrated that they are attracting a cadre of excellent researchers trained in the top universities around the world...

Lessons from Toxicology: Developing a 21st-Century Paradigm for Medical Research

Science.gov (United States)

Austin, Christopher P.; Balapure, Anil K.; Birnbaum, Linda S.; Bucher, John R.; Fentem, Julia; Fitzpatrick, Suzanne C.; Fowle, John R.; Kavlock, Robert J.; Kitano, Hiroaki; Lidbury, Brett A.; Muotri, Alysson R.; Peng, Shuang-Qing; Sakharov, Dmitry; Seidle, Troy; Trez, Thales; Tonevitsky, Alexander; van de Stolpe, Anja; Whelan, Maurice; Willett, Catherine

2015-01-01

Summary Biomedical developments in the 21st century provide an unprecedented opportunity to gain a dynamic systems-level and human-specific understanding of the causes and pathophysiologies of disease. This understanding is a vital need, in view of continuing failures in health research, drug discovery, and clinical translation. The full potential of advanced approaches may not be achieved within a 20th-century conceptual framework dominated by animal models. Novel technologies are being integrated into environmental health research and are also applicable to disease research, but these advances need a new medical research and drug discovery paradigm to gain maximal benefits. We suggest a new conceptual framework that repurposes the 21st-century transition underway in toxicology. Human disease should be conceived as resulting from integrated extrinsic and intrinsic causes, with research focused on modern human-specific models to understand disease pathways at multiple biological levels that are analogous to adverse outcome pathways in toxicology. Systems biology tools should be used to integrate and interpret data about disease causation and pathophysiology. Such an approach promises progress in overcoming the current roadblocks to understanding human disease and successful drug discovery and translation. A discourse should begin now to identify and consider the many challenges and questions that need to be solved. PMID:26523530

Life extension of the St. Lucie unit 1 reactor vessel

International Nuclear Information System (INIS)

Rowan, G.A.; Sun, J.B.; Mott, S.L.

1991-01-01

In late 1989, Florida Power and Light Company (FP and L) established the policy that St. Lucie unit 1 should not be prevented from achieving a 60-yr operating life by reactor vessel embrittlement. A 60-yr operating life means that the plant would be allowed to operate until the year 2036, which is 20 years beyond the current license expiration date of 2016. Since modifications to the reactor vessel and its components are projected to be expensive, the desire of FP and L management was to achieve this lifetime extension through the use of fuel management and proven technology. The following limitations were placed on any acceptable method for achieving this lifetime extension capability: low fuel cycle cost; low impact on safety parameters; very little or no operations impact; and use of normal reactor materials. A task team was formed along with the Advanced Nuclear Fuels Company (ANF) to develop a vessel-life extension program

Proceedings of the 21st Seismic Research Symposium: Technologies for Monitoring The Comprehensive Nuclear Test-Ban Treaty

Energy Technology Data Exchange (ETDEWEB)

Warren, N. Jill [Editor

1999-09-21

These proceedings contain papers prepared for the 21st Seismic Research Symposium: Technologies for Monitoring The Comprehensive Nuclear-Test-Ban Treaty, held 21-24 September 1999 in Las Vegas, Nevada. These papers represent the combined research related to ground-based nuclear explosion monitoring funded by the National Nuclear Security Administration (NNSA), Defense Threat Reduction Agency (DTRA), Air Force Technical Applications Center (AFTAC), Department of Defense (DoD), the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO), and other invited sponsors. The scientific objectives of the research are to improve the United States capability to detect, locate, and identify nuclear explosions. The purpose of the meeting is to provide the sponsoring agencies, as well as potential users, an opportunity to review research accomplished during the preceding year and to discuss areas of investigation for the coming year. For the researchers, it provides a forum for the exchange of scientific information toward achieving program goals, and an opportunity to discuss results and future plans. Paper topics include: seismic regionalization and calibration; detection and location of sources; wave propagation from source to receiver; the nature of seismic sources, including mining practices; hydroacoustic, infrasound, and radionuclide methods; on-site inspection; and data processing.

Dental Health Services Research Unit celebrates 30 years: Report of conference to mark the 30th anniversary of the Dental Health Services Research Unit (DHSRU) at Dundee, held on 1st December 2008.

Science.gov (United States)

Eaton, Kenneth A; Pitts, Nigel B

2009-04-01

Over the years, several members of the staff of the Dental Health Services Research Unit (DHSRU) at Dundee have published papers in Primary Dental Care. Furthermore, its Director, Professor Nigel Pitts, together with Drs Jan Clarkson and Gail Topping have co-edited a number of the Faculty of General Dental Practice (UK)'s standards manuals and contributed to others. It had been suggested to the Unit by several parties that, having been in funded existence for some 30 years, it would be appropriate to mark this anniversary with a conference to explore 'Dental Health Services Research: After 30 years, what was the impact, what have we learned and where are we going?' So, following a range of consultations, the conference was convened at the West Park Conference Centre in Dundee with a mixed audience representing both dental research and dental practice.

76 FR 48797 - Notice of the Advisory Committee on Biotechnology and 21st Century Agriculture Meeting

Science.gov (United States)

2011-08-09

... DEPARTMENT OF AGRICULTURE Agricultural Research Service Notice of the Advisory Committee on Biotechnology and 21st Century Agriculture Meeting AGENCY: Office of the Under Secretary, Research, Education... the Federal Advisory Committee Act, 5 U.S.C. App., the United States Department of Agriculture...

Epidemic Emergence in the United States of Escherichia coli Sequence Type 131-H30 (ST131-H30), 2000 to 2009.

Science.gov (United States)

Johnson, James R; Porter, Stephen; Thuras, Paul; Castanheira, Mariana

2017-08-01

The H 30 subclone of Escherichia coli sequence type 131 (ST131- H 30) has become the leading antimicrobial resistance E. coli lineage in the United States and often exhibits resistance to one or both of the two key antimicrobial classes for treating Gram-negative infections, extended-spectrum cephalosporins (ESCs) and fluoroquinolones (FQs). However, the timing of and reasons for its recent emergence are inadequately defined. Accordingly, from E. coli clinical isolates collected systematically across the United States by the SENTRY Antimicrobial Surveillance Program in 2000, 2003, 2006, and 2009, 234 isolates were selected randomly, stratified by year, within three resistance categories: (i) ESC-reduced susceptibility, regardless of FQ phenotype (ESC-RS); (ii) FQ resistance, ESC susceptible (FQ-R); and (iii) FQ susceptible, ESC susceptible (FQ-S). Susceptibility profiles, phylogroup, ST, ST131 subclone, and virulence genotypes were determined, and temporal trends and between-variable associations were assessed statistically. From 2000 to 2006, concurrently with the emergence of ESC-RS and FQ-R strains, the prevalence of (virulence-associated) phylogroup B2 among such strains also rose dramatically, due entirely to rapid emergence of ST131, especially H 30. By 2009, H 30 was the dominant E. coli lineage overall (22%), accounting for a median of 43% of all single-agent and multidrug resistance (68% for ciprofloxacin). H 30's emergence increased the net virulence gene content of resistant (especially FQ-R) isolates, giving stable overall virulence gene scores despite an approximately 4-fold expansion of the historically less virulent resistant population. These findings define more precisely the timing and tempo of H 30's emergence in the United States, identify possible reasons for it, and suggest potential consequences, including more frequent and/or aggressive antimicrobial-resistant infections. Copyright © 2017 American Society for Microbiology.

77 FR 11064 - Notice of the Advisory Committee on Biotechnology and 21st Century Agriculture Meeting

Science.gov (United States)

2012-02-24

... DEPARTMENT OF AGRICULTURE Agricultural Research Service Notice of the Advisory Committee on Biotechnology and 21st Century Agriculture Meeting AGENCY: Office of the Under Secretary, Research, Education... with the Federal Advisory Committee Act, 5 U.S.C. App. 2, the United States Department of Agriculture...

Home of the 151st Air Refueling Wing

Science.gov (United States)

History HRA Alley Public Affairs SAPR Units Contact Us Search 151st ARW: 151st ARW The Roland R. Wright woman in the profession of arms President Trump visits Roland R. Wright Air National Guard Base 151st Commentaries Women's History Month: looking around as important as looking back Veterans Day: Pay tribute with

Re-visioning the doctoral research degree in nursing in the United Kingdom.

Science.gov (United States)

Burton, Christopher R; Duxbury, Joy; French, Beverley; Monks, Rob; Carter, Bernie

2009-05-01

In the light of concerns about the wider social and economic value of the PhD training programme, this article discusses the challenges being directed primarily at the traditional doctoral programme of study. While the PhD is primarily concerned with the student making an original contribution to knowledge, the value-added component of the doctoral research degree needs to respond to the needs of a wider market of purchasers, and to meet practice and policy requirements for research leadership. The United Kingdom Research Councils (UK GRAD, 2001. Joint Skills Statement of Skills Training Requirements. Available at http://www.grad.ac.uk/downloads/documents/general/Joint%20Skills%20Statementpdf. (last accessed 1st April 2008.) suggest a range of seven skill domains over and above research design and management that should be offered to students. The seven domains are research skills and techniques, participation in the research environment, research management, personal effectiveness, communication, networking and team working, and career management. This article develops and extends these skill domains for the current healthcare context and considers how these should guide the development and evaluation of the value-added components of doctoral research degree programmes in nursing. The challenges that these issues present to academic departments are also discussed. Our conclusion is that PhD research training needs re-visioning and broadening so that the students' experience includes these value-added components.

Final Report for the 1st Surveillance Test of the Reactor Pressure Vessel Material (Capsule 2) of Ulchin Nuclear Power Plant Unit 4

Energy Technology Data Exchange (ETDEWEB)

Chang, Kee Ok; Kim, Byoung Chul; Lee, Sam Lai (and others)

2007-04-15

Surveillance testing for reactor vessel materials is performed in order to evaluate the irradiation embrittlement due to neutrons during operation and set the condition of safe operation of nuclear reactor. The 1st surveillance testing was performed completely by Korea Atomic Energy Research Institute at Daejon after the capsule was transported from Ulchin site including its removal from reactor. Fast neutron fluences for capsules were calculated and various testing including mechanical and chemistry analysis were performed in order to evaluate the integrity of Ulchin Unit 4 reactor vessel during the operation until life time. The evaluation results are as follows; Fast neutron fluences for capsule 2 is 4.306E+18n/cm{sup 2}. The bias factor, the ratio of calculation/measurement, was 0.918 for the 1st testing and the calculational uncertainty,7.0% satisfied the requirement of USNRC Reg.Guide 1.190, 20%. The best estimated neutron fluence for reactor vessel inside surface was 3.615E+18n/cm{sup 2} based on the end of 6th fuel cycle and it was predicted that the fluences of vessel inside surface at 16 and 32EFPY would reach 8.478E+18 and 1.673E+19n/cm{sup 2} based on the current calculation. The result through this analysis for Ulchin Unit 4 showed that there would be no problem for the pressurized thermal shock(PTS) during the operation until design life.

Final Report for the 1st Surveillance Test of the Reactor Pressure Vessel Material (CAPSULE 2) of Ulchin Nuclear Power Plant Unit 3

Energy Technology Data Exchange (ETDEWEB)

Chang, Kee Ok; Kim, Byoung Chul; Lee, Sam Lai (and others)

2006-12-15

Surveillance testing for reactor vessel materials is performed in order to evaluate the irradiation embrittlement due to neutrons during operation and set the condition of safe operation of nuclear reactor. The 1st surveillance testing was performed completely by Korea Atomic Energy Research Institute at Taejon after the capsule was transported from Ulchin site including its removal from reactor. Fast neutron fluences for capsules were calculated and various testing including mechanical and chemistry analysis were performed in order to evaluate the integrity of Ulchin unit 3 reactor vessel during the operation until life time. The evaluation results are as follows; Fast neutron fluences for capsule 2 is 4.674E 18n/cm{sup 2}. The bias factor, the ratio of calculation/measurement, was 0.920 for the 1st testing and the calculational uncertainty,7.0% satisfied the requirement of USNRC Reg.Guide 1.190, 20%. The best estimated neutron fluence for reactor vessel inside surface was 3.913E 18n/cm{sup 2} based on the end of 6th fuel cycle and it was predicted that the fluences of vessel inside surface at 16 and 32EFPY would reach 9.249E 18 and 1.834E 19n/cm{sup 2} based on the current calculation. The result through this analysis for Ulchin unit 3 showed that there would be no problem for the pressurized thermal shock(PTS) during the operation until design life.

Geographic Information System (GIS) characterization of historical seagrass coverage in St. Andrew Bay, Florida, 1953 (NODC Accession 0000608)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Graphical representation of historical seagrass coverage in St. Andrew Bay from United States Geological Survey/National Wetlands Research Center (USGS/NWRC) in...

Provide for the Common Defence: Rebalancing Constitutional War Powers in the 21st Century

Science.gov (United States)

2015-04-13

followed those with an additional declarations against Bulgaria, Hungary, and Romania in June 1942. Congressional Research Service, Instances of Use...Public Papers of the Presidents of the United States: Administration of William J. Clinton: 1995, no. 2, 1917- 1918 . 31 Cong. Rec., 104th Cong., 1st

Patterns of research utilization on patient care units

Directory of Open Access Journals (Sweden)

Lander Janice

2008-06-01

Full Text Available Abstract Background Organizational context plays a central role in shaping the use of research by healthcare professionals. The largest group of professionals employed in healthcare organizations is nurses, putting them in a position to influence patient and system outcomes significantly. However, investigators have often limited their study on the determinants of research use to individual factors over organizational or contextual factors. Methods The purpose of this study was to examine the determinants of research use among nurses working in acute care hospitals, with an emphasis on identifying contextual determinants of research use. A comparative ethnographic case study design was used to examine seven patient care units (two adult and five pediatric units in four hospitals in two Canadian provinces (Ontario and Alberta. Data were collected over a six-month period by means of quantitative and qualitative approaches using an array of instruments and extensive fieldwork. The patient care unit was the unit of analysis. Drawing on the quantitative data and using correspondence analysis, relationships between various factors were mapped using the coefficient of variation. Results Units with the highest mean research utilization scores clustered together on factors such as nurse critical thinking dispositions, unit culture (as measured by work creativity, work efficiency, questioning behavior, co-worker support, and the importance nurses place on access to continuing education, environmental complexity (as measured by changing patient acuity and re-sequencing of work, and nurses' attitudes towards research. Units with moderate research utilization clustered on organizational support, belief suspension, and intent to use research. Higher nursing workloads and lack of people support clustered more closely to units with the lowest research utilization scores. Conclusion Modifiable characteristics of organizational context at the patient care unit

CDC WONDER: Population - Bridged-Race July 1st Estimates

Data.gov (United States)

U.S. Department of Health & Human Services — The Population - Bridged-Race July 1st Estimates online databases report bridged-race population estimates of the July 1st resident population of the United States,...

1st International Symposium and 10th Balkan Conference on Operational Research

CERN Document Server

Sifaleras, Angelo; Georgiadis, Christos; Papathanasiou, Jason; Stiakakis, Emmanuil

2013-01-01

Over the past two decades, the Balkan Conference on Operational Research (BALCOR) has facilitated the exchange of scientific and technical information on the subject of Operations Research and related fields such as Mathematical Programming, Game Theory, Multiple Criteria Decision Analysis, Information Systems, Data Mining, and more, in order to promote international scientific cooperation.  The contributed papers contained in this volume consist of 25 selected research papers based on results presented at the 10th Balkan Conference & 1st International Symposium on Operational Research in Thessalonike, Greece. Subjects include, but do not restrict to, the development of theory and mathematical models for Operations Research, theory and applications of Combinatorial Optimization, Supply Chain Optimization, and Military Operations Research.  These carefully selected papers present important recent developments and modern applications, and will serve as excellent reference for students, researchers, and pr...

NASA-UVA Light Aerospace Alloy and Structures Technology Program (LA2ST). Research on Materials for the High Speed Civil Transport

Science.gov (United States)

Gangloff, Richard P.; Starke, Edgar A., Jr.; Kelly, Robert G.; Scully, John R.; Stoner, Glenn E.; Wert, John A.

1997-01-01

Since 1986, the NASA-Langley Research Center has sponsored the NASA-UVa Light Alloy and Structures Technology (LA2ST) Program at the University of Virginia (UVa). The fundamental objective of the LA2ST program is to conduct interdisciplinary graduate student research on the performance of next generation, light-weight aerospace alloys, composites and thermal gradient structures. The LA2ST program has aimed to product relevant data and basic understanding of material mechanical response, environmental/corrosion behavior, and microstructure; new monolithic and composite alloys; advanced processing methods; measurement and modeling advances; and a pool of educated graduate students for aerospace technologies. The scope of the LA2ST Program is broad. Research areas include: (1) Mechanical and Environmental Degradation Mechanisms in Advanced Light Metals and Composites, (2) Aerospace Materials Science, (3) Mechanics of materials for Aerospace Structures, and (4) Thermal Gradient Structures. A substantial series of semi-annual progress reports issued since 1987 documents the technical objectives, experimental or analytical procedures, and detailed results of graduate student research in these topical areas.

Design of a new research reactor : 1st year conceptual design

International Nuclear Information System (INIS)

Park, Cheol; Lee, B. C.; Chae, H. T.

2004-01-01

A new research reactor model satisfying the strengthened regulatory environments and the changed circumstances around nuclear society should be prepared for the domestic and international demand of research reactor. This can also lead to the improvement of technologies and fostering manpower obtained during the construction and the operation of HANARO. In this aspect, this study has been launched and the 1st year conceptual design has been carried out in 2003. The major tasks performed at the first year of conceptual design stage are as follows; Establishments of general design requirements of research reactors and experimental facilities, Establishment of fuel and reactor core concepts, Preliminary analysis of reactor physics and thermal-hydraulics for conceptual core, Conceptual design of reactor structure and major systems, International cooperation to establish foundations for exporting

Galleria mellonella infection model demonstrates high lethality of ST69 and ST127 uropathogenic E. coli.

Directory of Open Access Journals (Sweden)

Majed F Alghoribi

Full Text Available Galleria mellonella larvae are an alternative in vivo model for investigating bacterial pathogenicity. Here, we examined the pathogenicity of 71 isolates from five leading uropathogenic E. coli (UPEC lineages using G. mellonella larvae. Larvae were challenged with a range of inoculum doses to determine the 50% lethal dose (LD50 and for analysis of survival outcome using Kaplan-Meier plots. Virulence was correlated with carriage of a panel of 29 virulence factors (VF. Larvae inoculated with ST69 and ST127 isolates (10(4 colony-forming units/larvae showed significantly higher mortality rates than those infected with ST73, ST95 and ST131 isolates, killing 50% of the larvae within 24 hours. Interestingly, ST131 isolates were the least virulent. We observed that ST127 isolates are significantly associated with a higher VF-score than isolates of all other STs tested (P≤0.0001, including ST69 (P<0.02, but one ST127 isolate (strain EC18 was avirulent. Comparative genomic analyses with virulent ST127 strains revealed an IS1 mediated deletion in the O-antigen cluster in strain EC18, which is likely to explain the lack of virulence in the larvae infection model. Virulence in the larvae was not correlated with serotype or phylogenetic group. This study illustrates that G. mellonella are an excellent tool for investigation of the virulence of UPEC strains. The findings also support our suggestion that the incidence of ST127 strains should be monitored, as these isolates have not yet been widely reported, but they clearly have a pathogenic potential greater than that of more widely recognised clones, including ST73, ST95 or ST131.

Research of nuclear energy on the 21st Century Center of Excellence (COE) Program

International Nuclear Information System (INIS)

Sekimoto, Hiroshi; Yamamoto, Ichiro

2003-01-01

COE is an abbreviation of 'Center of Excellence' and the '21st Century COE Program' is project begun by the Ministry of Education, Culture, Sports, Science, and Technology (MECSST) to make a trigger to grow some research strongholds with international competitive power by activating mutual competition of collages and universities. This program aims to form research and educational strongholds with the highest level in the world at every scholarship fields to a collage or a university in Japan, to intend to grow creative specialists capable of upgrading research level and leading research world, and to progress strong assistance to promote collages- and universities-making with international competitive power and individuality. In 2003 fiscal year, two research programs related to nuclear energy were selected by the Committee of 21st Century COE Program such as 'an innovative reactor supporting suitable development of the world' in the mechanical, engineering and other technology field and 'future to be cultivated by isotopes' in the interdisciplinary, composite and new region field. The first program aims to construct the concept of system of innovative reactor and separation nuclear transformation for zero release of radioactive waste and to research the necessary technologies. The second program is covered isotope science and it consists of two main researches such as 1) the fundamental researches: a) separation and creation of isotopes, b) measurement technologies with nano size and c) isotope materials, and 2) the harmonized development researches: a) environment and bioscience and b) culture information and creation of quantum computer. (S.Y.)

Research at the Dairy and Functional Foods Research Unit

Science.gov (United States)

Dr. Peggy Tomasula is Research Leader of the Dairy and Functional Foods Research Unit (DFFRU), ARS, USDA, Wyndmoor, PA, a group that includes 11 Research Scientists, 4 of whom are Lead Scientists (LS), 13 support scientists, and 3 Retired Collaborators. The mission of the DFFRU is to solve critical ...

The Uranium Chemistry Research Unit

International Nuclear Information System (INIS)

Anon.

1983-01-01

The article discusses the research work done at the Uranium Chemistry Research Unit of the University of Port Elizabeth. The initial research programme dealt with fundamental aspects of uranium chemistry. New uranium compounds were synthesized and their chemical properties were studied. Research was also done to assist the mining industry, as well as on nuclear medicine. Special mentioning is made of the use of technetium for medical diagnosis and therapy

EPA-WERF Cooperative Agreement: Innovation and Research for Water Infrastructure for the 21st Century

Science.gov (United States)

This is a brief slide presentation that will provide an overview of several projects that are being conducted in EPA-WERF Cooperative Agreement, Innovation and Research for Water Infrastructure for the 21st Century. The cooperative agreement objectives are to produce, evaluate, &...

The Budapest research reactor as an advanced research facility for the early 21st century

International Nuclear Information System (INIS)

Vidovszky, I.

2001-01-01

The Budapest Research Reactor, Hungary's first nuclear facility was originally put into operation in 1959. The reactor serves for: basic and applied research, technological and commercial applications, education and training. The main goal of the reactor is to serve neutron research. This unique research possibility is used by a broad user community of Europe. Eight instruments for neutron scattering, radiography and activation analyses are already used, others (e.g. time of flight spectrometer, neutron reflectometer) are being installed. The majority of these instruments will get a much improved utilization when the cold neutron source is put into operation. In 1999 the Budapest Research Reactor was operated for 3129 full power hours in 14 periods. The normal operation period took 234 hours (starting Monday noon and finishing Thursday morning). The entire production for the year 1999 was 1302 MW days. This is a slightly reduced value, due to the installation of the cold neutron source. For the year 2000 a somewhat longer operation is foreseen (near to 4000 hours), as the cold neutron source will be operational. The operation of the reactor is foreseen at least up to the end of the first decade of the 21 st century. (author)

The Medical Research Council (UK)/Uganda Virus Research Institute Uganda Research Unit on AIDS--'25 years of research through partnerships'.

Science.gov (United States)

Kaleebu, P; Kamali, A; Seeley, J; Elliott, A M; Katongole-Mbidde, E

2015-02-01

For the past 25 years, the Medical Research Council/Uganda Virus Research Institute Uganda Research Unit on AIDS has conducted research on HIV-1, coinfections and, more recently, on non-communicable diseases. Working with various partners, the research findings of the Unit have contributed to the understanding and control of the HIV epidemic both in Uganda and globally, and informed the future development of biomedical HIV interventions, health policy and practice. In this report, as we celebrate our silver jubilee, we describe some of these achievements and the Unit's multidisciplinary approach to research. We also discuss the future direction of the Unit; an exemplar of a partnership that has been largely funded from the north but led in the south. © 2014 The Authors. Tropical Medicine & International Health Published by John Wiley & Sons Ltd.

Aligning Business and Education: 21st Century Skill Preparation

Science.gov (United States)

Campbell, Charles L., Jr.; Kresyman, Shelley

2015-01-01

The purpose of this paper is to explore stakeholder perceptions concerning four key 21st century skills required for graduates to be successful in today's workplace, and to report on common themes surrounding how a post-secondary school in the Southwest United States is preparing graduates with predominant 21st Century skills: interpersonal…

FY 2006 annual report. 21st century COE program isotope science and engineering from basics to applications

International Nuclear Information System (INIS)

2007-01-01

The 06' activity on 21st century COE program, Nagoya University, Isotopes open the future' is reported. The contents are: Research and educational execution planning; Operational reports (research activities, educational activities, international conferences, etc.); Research activities (1. the basic research field...isotope separation, isotope production, isotope measurement, and isotope materials, 2. the composite and development field...isotopes in biology, cultural science, and environment, 3. the young researchers unit for composite research, 4. research contributions); Educational activities (1. programs for assist of young researchers, 2. lectures on English, 3. lectures for postgraduate students). (J.P.N.)

Italian research on Antarctic atmosphere: 1st workshop. Ricerche italiane sull'atmosfera antartica: 1o workshop

Energy Technology Data Exchange (ETDEWEB)

Colacino, M. (ed.); Giovannelli, G. (ed.); Stefanutti, L. (ed.)

1989-01-01

The papers and reports, presented at this 1st workshop on 'Italian research on antarctic atmosphere', deal with several main topics: meteorology and climatology, aerosol and tropospheric clouds, planetary boundary layer, chemical-physic stratospheric property, aeronomy. They define the stage of development of Italian research in this area after 3 years of activity in Antarctica.

Technology Roadmap for the 21st Century Truck Program, a government-industry research partnership

Energy Technology Data Exchange (ETDEWEB)

None

2000-12-01

The 21st Century Truck Program has been established as a government-industry research partnership to support the development and implementation of commercially viable technologies that will dramatically cut fuel use and emissions of commercial trucks and buses while enhancing their safety and affordability as well as maintaining or enhancing performance. The innovations resulting from this program will reduce dependence on foreign oil, improve our nation's air quality, provide advanced technology for military vehicles, and enhance the competitiveness of the U.S. truck and bus industry while ensuring safe and affordable freight and bus transportation for the nation's economy. This Technology Roadmap for the 21st Century Truck Program has been prepared to guide the development of the technical advancements that will enable the needed improvements in commercial truck fuel economy, emissions, and safety.

Emergence of hospital- and community-associated panton-valentine leukocidin-positive methicillin-resistant Staphylococcus aureus genotype ST772-MRSA-V in Ireland and detailed investigation of an ST772-MRSA-V cluster in a neonatal intensive care unit.

LENUS (Irish Health Repository)

Brennan, Gráinne I

2012-03-01

Sequence type 22 (ST22) methicillin-resistant Staphylococcus aureus (MRSA) harboring staphylococcal cassette chromosome mec (SCCmec) IV (ST22-MRSA-IV) has predominated in Irish hospitals since the late 1990s. Six distinct clones of community-associated MRSA (CA-MRSA) have also been identified in Ireland. A new strain of CA-MRSA, ST772-MRSA-V, has recently emerged and become widespread in India and has spread into hospitals. In the present study, highly similar MRSA isolates were recovered from seven colonized neonates in a neonatal intensive care unit (NICU) in a maternity hospital in Ireland during 2010 and 2011, two colonized NICU staff, one of their colonized children, and a NICU environmental site. The isolates exhibited multiantibiotic resistance, spa type t657, and were assigned to ST772-MRSA-V by DNA microarray profiling. All isolates encoded resistance to macrolides [msr(A) and mpb(BM)] and aminoglycosides (aacA-aphD and aphA3) and harbored the Panton-Valentine leukocidin toxin genes (lukF-PV and lukS-PV), enterotoxin genes (sea, sec, sel, and egc), and one of the immune evasion complex genes (scn). One of the NICU staff colonized by ST772-MRSA-V was identified as the probable index case, based on recent travel to India. Seven additional hospital and CA-ST772-MRSA-V isolates recovered from skin and soft tissue infections in Ireland between 2009 and 2011 exhibiting highly similar phenotypic and genotypic characteristics to the NICU isolates were also identified. The clinical details of four of these patients revealed connections with India through ethnic background or travel. Our study indicates that hospital-acquired and CA-ST772-MRSA-V is currently emerging in Ireland and may have been imported from India on several occasions.

Introduction to Future Wireless Networks research group's projects/activities (St. Petersburg)

CSIR Research Space (South Africa)

Lysko, Albert A

2017-05-01

Full Text Available , Peace, Safety and Security  Materials Science and manufacturing  Meraka Institute (Information and Communication Technology)  Modelling and Digital Science  Natural Resources and the Environment  Implementation Unit  National Research Centres... CSIR Units and Centres  Operating Units  Biosciences  Built Environment  Defence, Peace, Safety and Security  Materials Science and manufacturing  Meraka Institute (Information and Communication Technology)  Modelling and Digital...

ACRR fission product release tests: ST-1 and ST-2

International Nuclear Information System (INIS)

Allen, M.D.; Stockman, H.W.; Reil, K.O.; Grimley, A.J.; Camp, W.J.

1988-01-01

Two experiments (ST-1 and ST-2) have been performed in the Annular Core Research Reactor (ACRR) at Sandia National Laboratories (SNLA) to obtain time-resolved data on the release of fission products from irradiated fuels under light water reactor (LWR) severe accident conditions. Both experiments were conducted in a highly reducing environment at maximum fuel temperatures of greater than 2400 K. These experiments were designed specifically to investigate the effect of increased total pressure on fission product release; ST-1 was performed at approximately 0.16 MPa and ST-2 was run at 1.9 MPa, whereas other parameters were matched as closely as possible. Release rate data were measured for Cs, I, Ba, Sr, Eu, Te, and U. The release rates were higher than predicted by existing codes for Ba, Sr, Eu, and U. Te release was very low, but Te did not appear to be sequestered by the zircaloy cladding; it was evenly distributed in the fuel. In addition, in posttest analysis a unique fuel morphology (fuel swelling) was observed which may have enhanced fission product release, especially in the high pressure test (ST-2). These data are compared with analytical results from the CORSOR correlation and the VICTORIA computer model

Do stable non-ST-segment elevation acute coronary syndromes require admission to coronary care units?

Science.gov (United States)

van Diepen, Sean; Lin, Meng; Bakal, Jeffrey A; McAlister, Finlay A; Kaul, Padma; Katz, Jason N; Fordyce, Christopher B; Southern, Danielle A; Graham, Michelle M; Wilton, Stephen B; Newby, L Kristin; Granger, Christopher B; Ezekowitz, Justin A

2016-05-01

Clinical practice guidelines recommend admitting patients with stable non-ST-segment elevation acute coronary syndrome (NSTE ACS) to telemetry units, yet up to two-thirds of patients are admitted to higher-acuity critical care units (CCUs). The outcomes of patients with stable NSTE ACS initially admitted to a CCU vs a cardiology ward with telemetry have not been described. We used population-based data of 7,869 patients hospitalized with NSTE ACS admitted to hospitals in Alberta, Canada, between April 1, 2007, and March 31, 2013. We compared outcomes among patients initially admitted to a CCU (n=5,141) with those admitted to cardiology telemetry wards (n=2,728). Patients admitted to cardiology telemetry wards were older (median 69 vs 65years, PST-segment myocardial infarction or unstable angina. There were no differences in clinical outcomes observed between patients with NSTE ACS initially admitted to a ward or a CCU. These findings suggest that stable NSTE ACS may be managed appropriately on telemetry wards and presents an opportunity to reduce hospital costs and critical care capacity strain. Copyright © 2016 Elsevier Inc. All rights reserved.

Office of Naval Research-Interns in Biomolecular Sciences Multi-Institutional Research Enhancement Partnership Program: Research Leadership for the 21st Century

National Research Council Canada - National Science Library

Avila, Diana; Chigbu, Paulinus; Garcia-Rios, Mario; Wild, James R

2006-01-01

.... The participants are from four minority-serving teaching institutions: Jackson State University (JSU), Jackson, MS; St. Mary's University (StMU), San Antonio, TX); Texas A & M International University...

21st Century Skills Map: Geography

Science.gov (United States)

Partnership for 21st Century Skills, 2009

2009-01-01

This 21st Century Skills Map is the result of hundreds of hours of research, development and feedback from educators and business leaders across the nation. The Partnership for 21st Century Skills has issued this map for the core subject of Geography.

Research-based Curricula in the Context of 21st Century Data Science

Science.gov (United States)

Fox, P. A.

2017-12-01

When the Informatics revolution began again a little more than 10 years ago (longer for bio-informatics) geosciences (or Earth and Space Sciences) was paying attention via international attention from the Electronic Geophysical Year (eGY) and related endeavours (IPY, IYPE, IHY). The research agenda was in the spotlight, or moreso what Earth and Space Science informatics, cast in emergent escience or cyber-infrastructures, could benefit from was the main focus of attention and funding. At the time almost all "Xinformatics" efforts were novel in their discipline or traditionally defined. However, a broader research and education agenda was clearly needed. At the same time, a much more cross-disciplinary field; data science emerged. In this presentation, we relate the development, delivery and assessment of research oriented informatics, data science and their specializations into geoscience education in generak and as undertaken at RPI over the last nine years. We conclude with a longitudinal view of the impacts on career paths in the 21st century

St. Louis Airport site environmental report for calendar year 1989, St. Louis, Missouri

Energy Technology Data Exchange (ETDEWEB)

none,

1990-05-01

The environmental monitoring program, which began in 1984, continued during 1989 at the St. Louis Airport Site (SLAPS) in St. Louis County, Missouri. SLAPS and its vicinity properties, including ditches north and south of the site, were designated for cleanup as part of the Formerly Utilized Sites Remedial Action Program (FUSRAP), a United States Department of Energy (DOE) program to identify and decontaminate or otherwise control sites where residual radioactive material remains from the early years of the nation's atomic energy program. The monitoring program at SLAPS measures radon concentrations in air; external gamma dose rates; and uranium, thorium, and radium concentrations in surface water, groundwater, and sediment. Additionally, several nonradiological parameters are measured in groundwater. To assess the potential effect of SLAPS on public health, the potential radiation dose was estimated for a hypothetical maximally exposed individual. This report presents the findings of the environmental monitoring program conducted at the St. Louis Airport Site (SLAPS) during calendar year 1989. 19 refs., 13 figs., 14 tabs.

United Kingdom health research analyses and the benefits of shared data.

Science.gov (United States)

Carter, James G; Sherbon, Beverley J; Viney, Ian S

2016-06-24

To allow research organisations to co-ordinate activity to the benefit of national and international funding strategies requires assessment of the funding landscape; this, in turn, relies on a consistent approach for comparing expenditure on research. Here, we discuss the impact and benefits of the United Kingdom's Health Research Classification System (HRCS) in national landscaping analysis of health research and the pros and cons of performing large-scale funding analyses. The first United Kingdom health research analysis (2004/2005) brought together the 11 largest public and charity funders of health research to develop the HRCS and use this categorisation to examine United Kingdom health research. The analysis was revisited in 2009/2010 and again in 2014. The most recent quinquennial analysis in 2014 compiled data from 64 United Kingdom research organisations, accounting for 91% of all public/charitable health research funding in the United Kingdom. The three analyses summarise the United Kingdom's health research expenditure in 2004/2005, 2009/2010 and 2014, and can be used to identify changes in research activity and disease focus over this 10 year period. The 2004/2005 analysis provided a baseline for future reporting and evidence for a United Kingdom Government review that recommended the co-ordination of United Kingdom health research should be strengthened to accelerate the translation of basic research into clinical and economic benefits. Through the second and third analyses, we observed strategic prioritisation of certain health research activities and disease areas, with a strong trend toward increased funding for more translational research, and increases in specific areas such as research on prevention. The use of HRCS in the United Kingdom to analyse the research landscape has provided benefit both to individual participatory funders and in coordinating initiatives at a national level. A modest amount of data for each project is sufficient for a

33 CFR 110.250 - St. Thomas Harbor, Charlotte Amalie, V.I.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false St. Thomas Harbor, Charlotte... SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.250 St. Thomas Harbor, Charlotte Amalie.... Thomas, V.I. of the United States and approaches thereto, including all waters under its jurisdiction, as...

Korea Atomic Energy Research Institute (KAERI) in the 21st century

International Nuclear Information System (INIS)

Chang, In Soon; Lee, Mun-Ki

2001-01-01

Abstract. KAERI (Korea Atomic Energy Research Institute), a national nuclear research institute in the Republic of Korea, celebrated its fortieth anniversary last April. It has played a key role in the Korean nuclear history such that it: initiated and promoted the peaceful uses of nuclear energy in the Republic of Korea; maintained nuclear expertise on whole spectrum of nuclear field through conducting nuclear R and D programs, operating nuclear research facilities, and training and educating specialized nuclear personnel; founded a cornerstone of Korean nuclear industry by participating in the establishment of a nuclear engineering company and a nuclear fuel company and localizing nuclear fuel and reactor technology; and contributed to nuclear safety regulation by incubating a specialized nuclear regulatory body. Recently, to concentrate on nuclear R and D on advanced technology, KAERI went through management reform such as: the transfer of nuclear engineering divisions responsible for NSSS design and nuclear fuel design to nuclear industry in 1996; and the downsizing of manpower in 1998. Currently KAERI is in the challenging stage in terms of its missions and manpower. In the coming 21st century, KAERI is required to maintain the current R and D momentum and also to conduct priority-based research requiring concentrated effort. (author)

Prospects of Nuclear Energy in the United States in the 21st Century

International Nuclear Information System (INIS)

Newman, R. E.

1988-01-01

The Nuclear Industry is now over 40 years old and a proven, mature product has been developed. That proven mature product has evolve into a small set of standardized designs - designs based on evolution of the best and safest features, not revolutionary changes. Just as the product design must be standardized, the regulatory process must also be standardized. With a predictable regulatory environment and rate structure the economic advantages of Nuclear Power will be self-evident. The Nuclear Industry in the United States has had a history of cycles as the economy and need for power has changed. The need for electricity to support growth is a given. With a strong focus on the standardization of the process and the product, a competent engineering approach to safety, and improved economies, the 21st century will see nuclear power assume its appropriate role as a key source in the energy mix in the United States. Presenting a discussion dealing with the future is always a risky thing. One man's prognosis is another mans wild guess. Today, I would like to talk briefly on my views of the future, and especially my views on the Prospects for Nuclear Energy in the U. S. in that future. Though it is clear that nuclear energy will play a key role in fulfilling the energy needs of the world, the future of nuclear energy in the United States is not as clear. A discussion of the future of the U. S. Nuclear Industry is especially appropriate here today because I am firmly confident that the Republic of Korea will play a major role in that future. The world energy situation and the role of nuclear power has undergone a number of upsets in the last decade. Often we tend to dwell on the gloom of the past and overlook the strengths that the Nuclear Industry has developed. Presently over 437 gigawatts of electricity in the world is planned to be produced by 564 nuclear units. There are over 32 countries with commercial nuclear programs. One of the brightest of these being here in

Public and nonprofit funding for research on mental disorders in France, the United Kingdom, and the United States.

Science.gov (United States)

Chevreul, Karine; McDaid, David; Farmer, Carrie M; Prigent, Amélie; Park, A-La; Leboyer, Marion; Kupfer, David J; Durand-Zaleski, Isabelle

2012-07-01

To document the investments made in research on mental disorders by both government and nonprofit nongovernmental organizations in France, the United Kingdom, and the United States. An exhaustive survey was conducted of primary sources of public and nonprofit organization funding for mental health research for the year 2007 in France and the United Kingdom and for fiscal year 2007-2008 in the United States, augmented with an examination of relevant Web sites and publications. In France, all universities and research institutions were identified using the Public Finance Act. In the United Kingdom, we scrutinized Web sites and hand searched annual reports and grant lists for the public sector and nonprofit charitable medical research awarding bodies. In the United States, we included the following sources: the National Institutes of Health, other administrative entities within the Department of Health and Human Services (eg, Centers for Disease Control and Prevention), the Department of Education, the Department of Veterans Affairs, the Department of Defense, and the National Science Foundation and, for nonprofit funding, The Foundation Center. We included research on all mental disorders and substance-related disorders using the same keywords. We excluded research on mental retardation and dementia and on the promotion of mental well-being. We used the same algorithm in each country to obtain data for only mental health funding in situations in which funding had a broader scope. France spent $27.6 million (2%) of its health research budget on mental disorders, the United Kingdom spent $172.6 million (7%), and the United States spent $5.2 billion (16%). Nongovernmental funding ranged from 1% of total funding for mental health research in France and the United States to 14% in the United Kingdom. Funding for research on mental disorders accounts for low proportions of research budgets compared with funding levels for research on other major health problems, whereas

[General practice research units in Denmark: multidisciplinary research in support of practical work].

Science.gov (United States)

Reventlow, Susanne; Broholm, Katalin Alexa Király; Mäkelä, Marjukka

2014-01-01

In Denmark the general practice research units operating in connection with universities provide a home base, training and methodology support for researchers in the field from medical students to general practitioners carrying out practical work. Research issues frequently require a multidisciplinary approach and use of different kinds of materials. Problems arising from the practical work of general practitioners take priority in the wide selection of topics. The units have networked efficiently with organizations of general practitioners and medical education. The combination of research environments has created synergy benefiting everybody and increased the scientific productivity and visibility of the field.

The Microcomputer in the Clinical Nursing Research Unit

Science.gov (United States)

Schwirian, Patricia M.; Byers, Sandra R.

1982-01-01

This paper discusses the microcomputer in clinical nursing research. There are six general areas in which computers have been useful to nurses: nursing notes and charting; patient care plans; automated monitoring of high-tech nursing units; HIS and MIS systems; personnel distribution systems; and education. Three alternative models for the conduct of clinical nursing research in a hospital are described. The first is a centralized model relying on the bureaucratic structure of the hospital. Second is a decentralized network of professional nurses and research support personnel woven together by a Clinical Nurse Researcher, and third is a dedicated clinical nursing research unit. Microcomputers have five characteristics which make them vital tools for nurse researchers: user-friendliness; environment friendliness; low cost; ease of interface with other information systems; and range and quality of software.

The spirit of St. Lucie: nuclear plant built on schedule

International Nuclear Information System (INIS)

Derrickson, W.B.

1984-01-01

Florida Power and Light Company currently has four nuclear units in operation with St. Lucie Unit 2 being the last to receive an operating license in June, 1983. It's sister Unit 1 received its license in 1976 and has, through 1982, compiled one of the best operating records in the United States. The full power license for St. Lucie Unit 2 was received from the Nuclear Regulatory Commission (NRC) on June 10, 1983, just six years after construction began. The industry average for construction of nuclear plants in this time period is about 10 years. The success of the St. Lucie Unit 2 project can be at least in part attributed to planning the work, accurate and timely reporting of results via valid indicators, well trained and skilled personnel, and most of all, teamwork. During the course of the project the plant was constantly on or near schedule and always ahead of industry averages. This was done despite issuance of numerous regulations by the NRC (TMI), a 1979 hurricane which did considerable damage to the Reactor Auxiliary Building, labor problems, and an NRC schedule review team that determined the best that could be done was to complete the plant a year later. The final price tag is about $1.42 billion, including ''allowance for funds used during construction''. In operation to date the post core loading test program has been completed in less than two months, enabling the plant to be put into commercial operation only two months after its original scheduled date of May 28, 1983exclamation

Uranium chemistry research unit

International Nuclear Information System (INIS)

Anon.

1978-01-01

The initial field of research of this Unit, established in 1973, was the basic co-ordination chemistry of uranium, thorium, copper, cobalt and nickel. Subsequently the interest of the Unit extended to extractive metallurgy relating to these metals. Under the term 'co-ordination chemistry' is understood the interaction of the central transition metal ion with surrounding atoms in its immediate vicinity (within bonding distance) and the influence they have on each other - for example, structural studies for determining the number and arrangement of co-ordinated atoms and spectrophotometric studies to establish how the f electron energy levels of uranium are influenced by the environment. New types of uranium compounds have been synthesized and studied, and the behaviour of uranium ions in non-aqueous systems has also received attention. This work can be applied to the development and study of extractants and new extractive processes for uranium

Epidemic potential of Escherichia coli ST131 and Klebsiella pneumoniae ST258: a systematic review and meta-analysis

Science.gov (United States)

Dautzenberg, M J D; Haverkate, M R; Bonten, M J M; Bootsma, M C J

2016-01-01

Objectives Observational studies have suggested that Escherichia coli sequence type (ST) 131 and Klebsiella pneumoniae ST258 have hyperendemic properties. This would be obvious from continuously high incidence and/or prevalence of carriage or infection with these bacteria in specific patient populations. Hyperendemicity could result from increased transmissibility, longer duration of infectiousness, and/or higher pathogenic potential as compared with other lineages of the same species. The aim of our research is to quantitatively estimate these critical parameters for E. coli ST131 and K. pneumoniae ST258, in order to investigate whether E. coli ST131 and K. pneumoniae ST258 are truly hyperendemic clones. Primary outcome measures A systematic literature search was performed to assess the evidence of transmissibility, duration of infectiousness, and pathogenicity for E. coli ST131 and K. pneumoniae ST258. Meta-regression was performed to quantify these characteristics. Results The systematic literature search yielded 639 articles, of which 19 data sources provided information on transmissibility (E. coli ST131 n=9; K. pneumoniae ST258 n=10)), 2 on duration of infectiousness (E. coli ST131 n=2), and 324 on pathogenicity (E. coli ST131 n=285; K. pneumoniae ST258 n=39). Available data on duration of carriage and on transmissibility were insufficient for quantitative assessment. In multivariable meta-regression E. coli isolates causing infection were associated with ST131, compared to isolates only causing colonisation, suggesting that E. coli ST131 can be considered more pathogenic than non-ST131 isolates. Date of isolation, location and resistance mechanism also influenced the prevalence of ST131. E. coli ST131 was 3.2 (95% CI 2.0 to 5.0) times more pathogenic than non-ST131. For K. pneumoniae ST258 there were not enough data for meta-regression assessing the influence of colonisation versus infection on ST258 prevalence. Conclusions With the currently available data

The ConocoPhillips Center for a Sustainable WE2ST (Water-Energy Education, Science, and Technology): Lessons Learned from an Innovative Research-Education-Outreach Center at Colorado School of Mines

Science.gov (United States)

Hogue, T. S.; Blaine, A. C.; Martin, A. C.

2016-12-01

The ConocoPhillips Center for a Sustainable WE2ST (Water-Energy Education, Science, and Technology) is a testament to the power of collaboration and innovation. WE2ST began as a partnership between ConocoPhillips (foundation gift) and the Colorado School of Mines (CSM) with the goal of fostering solutions to water-energy challenges via education, research and outreach. The WE2ST center is a training ground for the next generation of water-energy-social scientists and engineers and is a natural fit for CSM, which is known for its expertise in water resources, water treatment technologies, petroleum engineering, geosciences, and hydrology. WE2ST has nine contributing faculty researchers that combine to create a web of expertise on sustainable energy and water resources. This research benefits unconventional energy producers, water-reliant stakeholders and the general public. Areas of focus for research include water sources (quality and quantity), integrated water-energy solution viability and risk, and social-corporate responsibility. The WE2ST Center currently provides annual support for 8-9 Graduate Fellows and 13 Undergraduate Scholars. Top-tier graduate students are recruited nationally and funded similar to an NSF Graduate Research Fellowship (GRF). Undergraduate Scholars are also recruited from across the CSM campus to gain experience in faculty laboratories and on research teams. All WE2ST students receive extensive professional skills training, leadership development, communication skills training, networking opportunities in the water-energy industries, and outreach opportunities in the community. The corner stone of the WE2ST Center is a focus on communication with the public. Both in social science research teams and in general interactions with the public, WE2ST seeks to be "an honest broker" amidst a very passionate and complex topic. WE2ST research is communicated by presentations at technical conferences, talking with people at public gatherings

Roegneria alashanica Keng: a species with the StStStYStY genome constitution.

Science.gov (United States)

Wang, Richard R-C; Jensen, Kevin B

2017-06-01

The genome constitution of tetraploid Roegneria alashanica Keng has been in question for a long time. Most scientific studies have suggested that R. alashanica had two versions of the St genome, St 1 St 2 , similar to that of Pseudoroegneria elytrigioides (C. Yen & J.L. Yang) B.R. Lu. A study, however, concluded that R. alashanica had the StY genome formula typical for tetraploid species of Roegneria. For the present study, R. alashanica, Elymus longearistatus (Bioss.) Tzvelev (StY genomes), Pseudoroegneria strigosa (M. Bieb.) Á. Löve (St), Pseudoroegneria libanoctica (Hackel) D.R. Dewey (St), and Pseudoroegneria spicata (Pursh) Á. Löve (St) were screened for the Y-genome specific marker B14(F+R) 269 . All E. longearistatus plants expressed intense bands specific to the Y genome. Only 6 of 10 R. alashanica plants exhibited relatively faint bands for the STS marker. Previously, the genome in species of Pseudoroegneria exhibiting such faint Y-genome specific marker was designated as St Y . Based on these results, R. alashanica lacks the Y genome in E. longearistatus but likely possess two remotely related St genomes, St and St Y . According to its genome constitution, R. alashanica should be classified in the genus Pseudoroenera and given the new name Pseudoroegneria alashanica (Keng) R.R.-C. Wang and K.B. Jensen.

Excellence in Radiation Research for the 21st Century (EIRR21): Description of an Innovative Research Training Program

International Nuclear Information System (INIS)

P'ng, Christine; Ito, Emma; How, Christine; Bezjak, Andrea; Bristow, Rob; Catton, Pam; Fyles, Anthony; Gospodarowicz, Mary; Jaffray, David; Kelley, Shana; Wong Shun; Liu Feifei

2012-01-01

Purpose: To describe and assess an interdisciplinary research training program for graduate students, postdoctoral fellows, and clinical fellows focused on radiation medicine; funded by the Canadian Institutes for Health Research since 2003, the program entitled “Excellence in Radiation Research for the 21st Century” (EIRR21) aims to train the next generation of interdisciplinary radiation medicine researchers. Methods and Materials: Online surveys evaluating EIRR21 were sent to trainees (n=56), mentors (n=36), and seminar speakers (n=72). Face-to-face interviews were also conducted for trainee liaisons (n=4) and participants in the international exchange program (n=2). Results: Overall response rates ranged from 53% (mentors) to 91% (trainees). EIRR21 was well received by trainees, with the acquisition of several important skills related to their research endeavors. An innovative seminar series, entitled Brainstorm sessions, imparting “extracurricular” knowledge in intellectual property protection, commercialization strategies, and effective communication, was considered to be the most valuable component of the program. Networking with researchers in other disciplines was also facilitated owing to program participation. Conclusions: EIRR21 is an innovative training program that positively impacts the biomedical community and imparts valuable skill sets to foster success for the future generation of radiation medicine researchers.

Excellence in Radiation Research for the 21st Century (EIRR21): Description of an Innovative Research Training Program

Energy Technology Data Exchange (ETDEWEB)

P' ng, Christine [Radiation Medicine Program, University Health Network, Toronto, Ontario (Canada); Ito, Emma [Radiation Medicine Program, University Health Network, Toronto, Ontario (Canada); Ontario Cancer Institute, Toronto, Ontario (Canada); How, Christine [Ontario Cancer Institute, Toronto, Ontario (Canada); Department of Medical Biophysics, University of Toronto, Toronto, Ontario (Canada); Bezjak, Andrea [Radiation Medicine Program, University Health Network, Toronto, Ontario (Canada); Department of Radiation Oncology, University of Toronto, Toronto, Ontario (Canada); Bristow, Rob [Radiation Medicine Program, University Health Network, Toronto, Ontario (Canada); Ontario Cancer Institute, Toronto, Ontario (Canada); Department of Medical Biophysics, University of Toronto, Toronto, Ontario (Canada); Department of Radiation Oncology, University of Toronto, Toronto, Ontario (Canada); Catton, Pam; Fyles, Anthony; Gospodarowicz, Mary [Radiation Medicine Program, University Health Network, Toronto, Ontario (Canada); Department of Radiation Oncology, University of Toronto, Toronto, Ontario (Canada); Jaffray, David [Radiation Medicine Program, University Health Network, Toronto, Ontario (Canada); Department of Medical Biophysics, University of Toronto, Toronto, Ontario (Canada); Department of Radiation Oncology, University of Toronto, Toronto, Ontario (Canada); Kelley, Shana [Department of Biochemistry, University of Toronto, Toronto, Ontario (Canada); Wong Shun [Department of Radiation Oncology, University of Toronto, Toronto, Ontario (Canada); Odette Cancer Center, Toronto, Ontario (Canada); Liu Feifei, E-mail: Fei-Fei.Liu@rmp.uhn.on.ca [Radiation Medicine Program, University Health Network, Toronto, Ontario (Canada); Ontario Cancer Institute, Toronto, Ontario (Canada); Department of Medical Biophysics, University of Toronto, Toronto, Ontario (Canada); Department of Radiation Oncology, University of Toronto, Toronto, Ontario (Canada)

2012-08-01

Purpose: To describe and assess an interdisciplinary research training program for graduate students, postdoctoral fellows, and clinical fellows focused on radiation medicine; funded by the Canadian Institutes for Health Research since 2003, the program entitled 'Excellence in Radiation Research for the 21st Century' (EIRR21) aims to train the next generation of interdisciplinary radiation medicine researchers. Methods and Materials: Online surveys evaluating EIRR21 were sent to trainees (n=56), mentors (n=36), and seminar speakers (n=72). Face-to-face interviews were also conducted for trainee liaisons (n=4) and participants in the international exchange program (n=2). Results: Overall response rates ranged from 53% (mentors) to 91% (trainees). EIRR21 was well received by trainees, with the acquisition of several important skills related to their research endeavors. An innovative seminar series, entitled Brainstorm sessions, imparting 'extracurricular' knowledge in intellectual property protection, commercialization strategies, and effective communication, was considered to be the most valuable component of the program. Networking with researchers in other disciplines was also facilitated owing to program participation. Conclusions: EIRR21 is an innovative training program that positively impacts the biomedical community and imparts valuable skill sets to foster success for the future generation of radiation medicine researchers.

Mapping Investments and Published Outputs in Norovirus Research: A Systematic Analysis of Research Funded in the United States and United Kingdom During 1997-2013.

Science.gov (United States)

Head, Michael G; Fitchett, Joseph R; Lichtman, Amos B; Soyode, Damilola T; Harris, Jennifer N; Atun, Rifat

2016-02-01

Norovirus accounts for a considerable portion of the global disease burden. Mapping national or international investments relating to norovirus research is limited. We analyzed the focus and type of norovirus research funding awarded to institutions in the United States and United Kingdom during 1997-2013. Data were obtained from key public and philanthropic funders across both countries, and norovirus-related research was identified from study titles and abstracts. Included studies were further categorized by the type of scientific investigation, and awards related to vaccine, diagnostic, and therapeutic research were identified. Norovirus publication trends are also described using data from Scopus. In total, US and United Kingdom funding investment for norovirus research was £97.6 million across 349 awards; 326 awards (amount, £84.9 million) were received by US institutions, and 23 awards (£12.6 million) were received by United Kingdom institutions. Combined, £81.2 million of the funding (83.2%) was for preclinical research, and £16.4 million (16.8%) was for translational science. Investments increased from £1.7 million in 1997 to £11.8 million in 2013. Publication trends showed a consistent temporal increase from 48 in 1997 to 182 in 2013. Despite increases over time, trends in US and United Kingdom funding for norovirus research clearly demonstrate insufficient translational research and limited investment in diagnostics, therapeutics, or vaccine research. © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.

21st Century Skills Map: The Arts

Science.gov (United States)

Dean, Colleen; Ebert, Christie M. Lynch; McGreevy-Nichols, Susan; Quinn, Betsy; Sabol, F. Robert; Schmid, Dale; Shauck, R. Barry; Shuler, Scott C.

2010-01-01

This 21st Century Skills Map is the result of hundreds of hours of research, development and feedback from educators and business leaders across the nation. The Partnership for 21st Century Skills has issued this map for the core subject of the Arts.

Summary Report of 1st Research Coordination Meeting on Development of Reference Database for Beta-delayed Neutron Emission

International Nuclear Information System (INIS)

Dillmann, Iris; Dimitriou, Paraskevi; Singh, Balraj

2014-03-01

A summary is given of the 1st Research Coordination Meeting of the new IAEA Coordinated Research Project (CRP) on Development of a Reference Database for Beta-delayed neutron emission data. Participants presented their work, reviewed the current status of the field with regards to individual precursors and aggregate data, and discussed the scope of the work to be undertaken. A list of priorities and task assignments was produced. (author)

ST Product Characteristics and Relationships with Perceptions and Behaviors among Rural Adolescent Males: A Qualitative Study

Science.gov (United States)

Couch, Elizabeth T.; Darius, Ellen F.; Walsh, Margaret M.; Chaffee, Benjamin W.

2017-01-01

Although smoking declines in the United States, the prevalence of male adolescent smokeless tobacco (ST; moist snuff and chewing tobacco) use remains unchanged. ST product characteristics, such as flavoring, packaging, and branding, could influence adolescents' ST initiation and continued use. This qualitative study examines the potential role of…

The 1st symposium of Research Center for Charged Particle Therapy on fundamental development of the charged particle therapy

International Nuclear Information System (INIS)

Soga, Fuminori

2002-06-01

This issue is the collection of the paper presented at the 1st Symposium of Research Center for Charged Particle Therapy on fundamental development of the charged particle therapy. The 31 of the presented papers are indexed individually. (J.P.N.)

Clinical Epidemiology Unit - overview of research areas

Science.gov (United States)

Clinical Epidemiology Unit (CEU) conducts etiologic research with potential clinical and public health applications, and leads studies evaluating population-based early detection and cancer prevention strategies

Impact of human-associated Escherichia coli clonal groups in Antarctic pinnipeds: presence of ST73, ST95, ST141 and ST131.

Science.gov (United States)

Mora, Azucena; García-Peña, Francisco Javier; Alonso, María Pilar; Pedraza-Diaz, Susana; Ortega-Mora, Luis Miguel; Garcia-Parraga, Daniel; López, Cecilia; Viso, Susana; Dahbi, Ghizlane; Marzoa, Juan; Sergeant, Martin J; García, Vanesa; Blanco, Jorge

2018-03-16

There is growing concern about the spreading of human microorganisms in relatively untouched ecosystems such as the Antarctic region. For this reason, three pinniped species (Leptonychotes weddellii, Mirounga leonina and Arctocephalus gazella) from the west coast of the Antartic Peninsula were analysed for the presence of Escherichia spp. with the recovery of 158 E. coli and three E. albertii isolates. From those, 23 harboured different eae variants (α1, β1, β2, ε1, θ1, κ, ο), including a bfpA-positive isolate (O49:H10-A-ST206, eae-k) classified as typical enteropathogenic E. coli. Noteworthy, 62 of the 158 E. coli isolates (39.2%) exhibited the ExPEC status and 27 (17.1%) belonged to sequence types (ST) frequently occurring among urinary/bacteremia ExPEC clones: ST12, ST73, ST95, ST131 and ST141. We found similarities >85% within the PFGE-macrorrestriction profiles of pinniped and human clinic O2:H6-B2-ST141 and O16:H5/O25b:H4-B2-ST131 isolates. The in silico analysis of ST131 Cplx genomes from the three pinnipeds (five O25:H4-ST131/PST43-fimH22-virotype D; one O16:H5-ST131/PST506-fimH41; one O25:H4-ST6252/PST9-fimH22-virotype D1) identified IncF and IncI1 plasmids and revealed high core-genome similarities between pinniped and human isolates (H22 and H41 subclones). This is the first study to demonstrate the worrisome presence of human-associated E. coli clonal groups, including ST131, in Antarctic pinnipeds.

21st Century Skills Map: World Languages

Science.gov (United States)

Partnership for 21st Century Skills, 2011

2011-01-01

This 21st Century Skills Map is the result of hundreds of hours of research, development and feedback from educators and business leaders across the nation. The Partnership for 21st Century Skills has issued this map for the core subject of World Languages. [Funding for this paper was provided by EF Education.

Toxic Hazards Research Unit 1989

Science.gov (United States)

1990-10-01

in monkeys/man. - Materials safety training. - Correct and legal housing for iaboratory animals. - The use of physiologically based pharmacokinetic...Whitmire, and E.R. Kinkeea. Presented at the 31st Navy Occupational Health and Preventive Medicina Workshop, Virginia Beach, VA, 11-16 March. 297 7• -7

Developing a clinical trial unit to advance research in an academic institution.

Science.gov (United States)

Croghan, Ivana T; Viker, Steven D; Limper, Andrew H; Evans, Tamara K; Cornell, Alissa R; Ebbert, Jon O; Gertz, Morie A

2015-11-01

Research, clinical care, and education are the three cornerstones of academic health centers in the United States. The research climate has always been riddled with ebbs and flows, depending on funding availability. During a time of reduced funding, the number and scope of research studies have been reduced, and in some instances, a field of study has been eliminated. Recent reductions in the research funding landscape have led institutions to explore new ways to continue supporting research. Mayo Clinic in Rochester, MN has developed a clinical trial unit within the Department of Medicine, which provides shared resources for many researchers and serves as a solution for training and mentoring new investigators and study teams. By building on existing infrastructure and providing supplemental resources to existing research, the Department of Medicine clinical trial unit has evolved into an effective mechanism for conducting research. This article discusses the creation of a central unit to provide research support in clinical trials and presents the advantages, disadvantages, and required building blocks for such a unit. Copyright © 2015 Mayo Clinic. Published by Elsevier Inc. All rights reserved.

Plant biology research and training for the 21st century

Energy Technology Data Exchange (ETDEWEB)

Kelly, K. [ed.

1992-12-31

The committee was assembled in response to a request from the National Science Foundation (NSF), the US Department of Agriculture (USDA), and the US Department of Energy (DoE). The leadership of these agencies asked the National Academy of Sciences through the National Research Council (NRC) to assess the status of plant-science research in the United States in light of the opportunities arising from advances inother areas of biology. NRC was asked to suggest ways of accelerating the application of these new biologic concepts and tools to research in plant science with the aim of enhancing the acquisition of new knowledge about plants. The charge to the committee was to examine the following: Organizations, departments, and institutions conducting plant biology research; human resources involved in plant biology research; graduate training programs in plant biology; federal, state, and private sources of support for plant-biology research; the role of industry in conducting and supporting plant-biology research; the international status of US plant-biology research; and the relationship of plant biology to leading-edge research in biology.

Plant biology research and training for the 21st century

Energy Technology Data Exchange (ETDEWEB)

Kelly, K. (ed.)

1992-01-01

The committee was assembled in response to a request from the National Science Foundation (NSF), the US Department of Agriculture (USDA), and the US Department of Energy (DoE). The leadership of these agencies asked the National Academy of Sciences through the National Research Council (NRC) to assess the status of plant-science research in the United States in light of the opportunities arising from advances inother areas of biology. NRC was asked to suggest ways of accelerating the application of these new biologic concepts and tools to research in plant science with the aim of enhancing the acquisition of new knowledge about plants. The charge to the committee was to examine the following: Organizations, departments, and institutions conducting plant biology research; human resources involved in plant biology research; graduate training programs in plant biology; federal, state, and private sources of support for plant-biology research; the role of industry in conducting and supporting plant-biology research; the international status of US plant-biology research; and the relationship of plant biology to leading-edge research in biology.

The Danish St. Croix Project

DEFF Research Database (Denmark)

J. Douma, Michael; Rasmussen, Anders Bo

2014-01-01

H. Seward, commonly viewed as an anti-colonizationist, was at least a mild proponent of colonization in its earliest stages. The paper demonstrates further that in the summer of 1862 the St. Croix colonization project was an important stepping stone in the Lincoln administration’s legal......Working from previously unknown sources in Danish archives, this article establishes for the first time the important role that the island of St. Croix played in the Lincoln Administration’s considerations on colonizing African Americans abroad. The paper argues that U.S. Secretary of State William....... The substantial conclusion of the paper is that, contrary to earlier perceptions in the historiography, African American colonization during the Civil War was not led and directed entirely from Washington. Rather, in this case, the Danish minister proposed a colonization plan and then worked with the United...

21st Century leadership skills for learning networks

NARCIS (Netherlands)

Basten, Floor; Evers, Arnoud; Geijsel, Femke; Vermeulen, Marjan

2018-01-01

Ultimate goal: to prepare pupils for a life in a society that requires 21st century skills and actions Immediate focus: teachers and principals develop 21st century skills in the practice of their work → together with researchers principals co-create tools to support teacher learning.

Surveys in 1961 on St. Thomas & St. Croix

DEFF Research Database (Denmark)

Dahl, Thorkel; Licht, Kjeld de Fine

Registration of towns and buildings erected during the Danish reign of the Caribbean Isles of St. Thomas, St. Jan and St. Croix 1671-1917 (now belonging to the USA under the name of Virgin Islands)....

Projected 21st century climate change for wolverine habitats within the contiguous United States

Energy Technology Data Exchange (ETDEWEB)

Peacock, Synte, E-mail: synte@ucar.edu [National Center for Atmospheric Research, 1850 Table Mesa Drive, Boulder, CO 80305 (United States)

2011-01-15

Ensembles of 21st century climate projections made using a state of the art global climate model are analyzed to explore possible changes in spring snow cover and summer air temperature in present-day wolverine habitats in the contiguous United States (US). Projected changes in both snow cover and temperature are presented for a range of future emissions scenarios, and implications for the continued survival of the wolverine in the contiguous US are discussed. It is shown that under a high or medium-low emissions scenario there are likely to be dramatic reductions in spring snow cover in present-day wolverine habitats. Under these scenarios there is also likely to be a concomitant increase in summer-time temperatures, with projected maximum daily August temperatures far above those currently tolerated by the wolverine. It is likely that the wolverine, with its many adaptations for cold weather and deep snow pack, would have great difficulty adapting to such changes. The results of the simulations presented here suggest that the very low numbers of wolverines currently living in the contiguous US will likely further decline in response to the deterioration of their habitat in coming decades.

Projected 21st century climate change for wolverine habitats within the contiguous United States

International Nuclear Information System (INIS)

Peacock, Synte

2011-01-01

Ensembles of 21st century climate projections made using a state of the art global climate model are analyzed to explore possible changes in spring snow cover and summer air temperature in present-day wolverine habitats in the contiguous United States (US). Projected changes in both snow cover and temperature are presented for a range of future emissions scenarios, and implications for the continued survival of the wolverine in the contiguous US are discussed. It is shown that under a high or medium-low emissions scenario there are likely to be dramatic reductions in spring snow cover in present-day wolverine habitats. Under these scenarios there is also likely to be a concomitant increase in summer-time temperatures, with projected maximum daily August temperatures far above those currently tolerated by the wolverine. It is likely that the wolverine, with its many adaptations for cold weather and deep snow pack, would have great difficulty adapting to such changes. The results of the simulations presented here suggest that the very low numbers of wolverines currently living in the contiguous US will likely further decline in response to the deterioration of their habitat in coming decades.

Increased serum concentrations of soluble ST2 predict mortality after burn injury.

Science.gov (United States)

Hacker, Stefan; Dieplinger, Benjamin; Werba, Gregor; Nickl, Stefanie; Roth, Georg A; Krenn, Claus G; Mueller, Thomas; Ankersmit, Hendrik J; Haider, Thomas

2018-06-27

Large burn injuries induce a systemic response in affected patients. Soluble ST2 (sST2) acts as a decoy receptor for interleukin-33 (IL-33) and has immunosuppressive effects. sST2 has been described previously as a prognostic serum marker. Our aim was to evaluate serum concentrations of sST2 and IL-33 after thermal injury and elucidate whether sST2 is associated with mortality in these patients. We included 32 burn patients (total body surface area [TBSA] >10%) admitted to our burn intensive care unit and compared them to eight healthy probands. Serum concentrations of sST2 and IL-33 were measured serially using an enzyme-linked immunosorbent assay (ELISA) technique. The mean TBSA was 32.5%±19.6%. Six patients (18.8%) died during the hospital stay. Serum analyses showed significantly increased concentrations of sST2 and reduced concentrations of IL-33 in burn patients compared to healthy controls. In our study cohort, higher serum concentrations of sST2 were a strong independent predictor of mortality. Burn injuries cause an increment of sST2 serum concentrations with a concomitant reduction of IL-33. Higher concentrations of sST2 are associated with increased in-hospital mortality in burn patients.

Three members of Medicago truncatula ST family are ubiquitous during development and modulated by nutritional status (MtST1) and dehydration (MtST2 and MtST3).

Science.gov (United States)

Albornos, Lucía; Martín, Ignacio; Labrador, Emilia; Dopico, Berta

2017-07-10

ShooT specific/Specific Tissue (ST) belong to a protein family of unknown function characterized by the DUF2775 domain and produced in specific taxonomic plant families, mainly Fabaceae and Asteraceae, with the Medicago truncatula ST family being the largest. The putative roles proposed for this family are cell elongation, biotic interactions, abiotic stress and N reserve. The aim of this work was to go deeper into the role of three M. truncatula ST proteins, namely ST1, ST2 and ST3. Our starting hypothesis was that each member of the family could perform a specific role, and hence, each ST gene would be subjected to a different type of regulation. The search for cis-acting regulatory elements (CREs) in silico in pST1, pST2 and pST3 promoters showed prevalence of tissue/organ specific motifs, especially root- and seed-specific ones. Light, hormone, biotic and abiotic related motifs were also present. None of these pSTs showed the same combination of CREs, or presented the same activity pattern. In general, pST activity was associated with the vascular cylinder, mainly in roots. Promoter activation was highly specific and dissimilar during reproductive development. The ST1, ST2 and ST3 transcripts accumulated in most of the organs and developmental stages analysed - decreasing with age - and expression was higher in the roots than in the aerial parts and more abundant in light-grown plants. The effect of the different treatments on transcript accumulation indicated that ST1 behaved differently from ST2 and ST3, mainly in response to several hormones and dehydration treatments (NaCl or mannitol), upon which ST1 transcript levels decreased and ST2 and ST3 levels increased. Finally, the ST1 protein was located in the cell wall whereas ST2 and ST3 were present both in the cytoplasm and in the cell wall. The ST proteins studied are ubiquitous proteins that could perform distinct/complementary roles in plant biology as they are encoded by differentially regulated genes

Infusing Active Learning into the Research Methods Unit

Science.gov (United States)

Bluestone, Cheryl

2007-01-01

The research methods unit of survey psychology classes introduces important concepts of scientific reasoning and fluency, making it an ideal course in which to deliver enhanced curricula. To increase interest and engagement, the author developed an expanded research methods and statistics module to give students the opportunity to explore…

The nursing professorial unit: translating acute and critical care nursing research

Directory of Open Access Journals (Sweden)

Martin Christensen

2017-11-01

Full Text Available Background and context: Implementation of current research in practice is challenging for ward-based nursing staff. However, university-based nursing academics are seen as the research experts and are perhaps well placed to support clinical nursing research. The problem lies with the divide between practice and academia; universities often use the clinical environment as the place to conduct research but this is often not translated effectively into practice. The development of a nursing professorial unit for acute and critical care was undertaken to meet this challenge. The unit’s key aim is to develop, mentor and support a nursing research culture that is wholly situated within and driven by the requirements of the clinical environment. Aim: The aim of this article is to offer some insights as to how staff set about engaging with and developing the nursing professorial unit to support nursing research in our local hospital. Conclusions: The article highlights how an effective and coordinated approach to supporting clinical nursing research is possible. The nursing professorial unit has been successful in bridging the divide between academia and practice by using a non-university approach to supporting nursing research. Instead we have adopted the philosophy that practice is the sole driver for research and as academics our role is to support that position. Implications for practice: The adoption of the nursing professorial unit model for supporting clinical nursing research is beneficial in closing the divide between clinical practice and the university The continual presence of the academics in the clinical environment has had a positive impact on research development and implementation in practice The nursing professorial unit has become an integral part of the nursing culture in the hospital environment

Artificial Intelligence Research in Australia -- A Profile

OpenAIRE

Smith, Elizabeth; Whitelaw, John

1987-01-01

Does the United States have a 51st state called Australia? A superficial look at the artificial intelligence (AI) research being done here could give that impression. A look beneath the surface, though, indicates some fundamental differences and reveals a dynamic and rapidly expanding AI community. General awareness of the Australian AI research community has been growing slowly for some time. AI was once considered a bit esoteric -- the domain of an almost lunatic fringe- but the large gover...

Situation Reports--Afghanistan, Bahrein, Brazil, Ecuador, Indonesia, Iraq, Morocco, Paraguay, People's Democratic Republic of Yemen, Peru, Qatar, Saudi Arabia, Sri Lanka, St. Christopher/Nevis, Sudan, United Arab Emirates, Yemen Arab Republic.

Science.gov (United States)

International Planned Parenthood Federation, London (England).

Data relating to population and family planning in 17 foreign countries are presented in these situation reports. Countries included are Afghanistan, Bahrein, Brazil, Ecuador, Indonesia, Iraq, Morocco, Paraguay, People's Democratic Republic of Yemen, Peru, Qatar, Saudi Arabia, Sri Lanka, St. Christopher/Nevis, Sudan, United Arab Emirates, and…

Science Unit Plans. PACE '94.

Science.gov (United States)

Schoon, Kenneth J., Ed.; Wiles, Clyde A., Ed.

This booklet contains mathematics unit plans for Biology, Chemistry, and Physical Science developed by PACE (Promoting Academic Excellence In Mathematics, Science & Technology for Workers of the 21st Century). Each unit plan contains suggested timing, objectives, skills to be acquired, workplace relationships, learning activities with suggested…

Cooperative Fish and Wildlife Research Units Program—2017 year in review

Science.gov (United States)

Organ, John F.; Thompson, John D.; Dennerline, Donald E.; Childs, Dawn E.

2018-02-08

The Cooperative Fish and Wildlife Research Units Program was involved in a number of notable events during 2017, many concerning our personnel. Dr. Barry Grand left his position as Leader of the Alabama Cooperative Fish and Wildlife Research Unit to become the Cooperative Units Program Supervisor for the South, replacing Dr. Kevin Whalen who took over as Supervisor for the West. We welcomed Dr. Sarah Converse who left the Patuxent Wildlife Research Center to become Leader of the Washington Cooperative Fish and Wildlife Research Unit. Dr. Amanda Rosenberger joined the Tennessee Cooperative Fishery Research Unit as Assistant Leader, transferring from the Missouri Cooperative Unit. Dr. Scott Carleton left his position as Assistant Unit Leader in New Mexico to become Chief of the Region 2 Migratory Bird Program of the U.S. Fish and Wildlife Service.We said farewell to many colleagues who retired. Their departure is bittersweet as we wish them health, happiness, and wellness in retirement. We will miss their companionship and the extraordinary contributions they have made to the Cooperative Fish and Wildlife Research Units Program and conservation.The Cooperative Fish and Wildlife Research Units Program has a record high number of vacant scientist positions due to a combination of retirements and base funding short-falls. These issues are affecting our ability to meet cooperator needs. Yet, we remain highly productive. For example, this year we released a report (https://doi.org/10.3133/cir1427) containing abstracts of nearly 600 of our research projects, covering thematic areas ranging from advanced technologies to wildlife diseases. We provided highly competent, trained scientists and natural resource managers for our cooperators’ workforce. We delivered technical training and guidance to professional practitioners. We provided critical information to cooperators for decisions on species status assessments and management of species of greatest conservation need

Constructing Learning-by-Doing Pedagogical Model for Delivering 21st Century Engineering Education

Directory of Open Access Journals (Sweden)

Ghassan Frache

2018-01-01

Full Text Available The United Arab Emirates (UAE is dedicated to establishing the best teaching and learning environment for students and staff across all higher education institutions. To heed this call, the engineering division adopted the Learning-by-Doing (LBD pedagogical philosophy for 21st Century education at the heart of its strategic directions. This study intends to explore how LBD is understood and practiced in UAE colleges and how 21st Century skills can be explicitly incorporated into its engineering curriculum by using constructive alignment as a pattern for instructional design. This work intends to investigate the general question: “What constructively aligned Learning-by-Doing pedagogical model, with the incorporation of 21st Century skills, needs to be developed to effectively teach and prepare engineering students at the Higher College of Technology, UAE for successful long-term employment in the global working economy?”. Using mixed method research design and input from its major stakeholders, student survey questionnaires, engineering instructors and dean structured interviews, overt class observation and syllabi examination have all been utilized for data triangulation. In conclusion, the study developed a collaborative LBD model tailor-fitted to the institution’s engineering program and to UAE’s culture.

ST2 IN REJECTION OF THE TRANSPLANTED HEART

Directory of Open Access Journals (Sweden)

O. P. Shevchenko

2015-01-01

Full Text Available This review summarizes the current literature devoted to the analysis of prognostic role of ST2 biomarker in rejection of the transplanted heart. ST2 is one of the most promising diagnostic markers of the development and severity of heart failure as well as the mortality risk in patients with cardiovascular diseases. ST2 is expressed in cardiomyocytes in response to a variety of pathological processes and mechanical damage to the heart, which allows diagnosing cardiovascular diseases before clinical manifestations. Presumably, measuring the level of ST2 in heart transplant may have diagnostic and prognostic value in the assessment of graft and risk of rejection. Currently, accumulated clinical data on the role of given biomarker in heart transplantation are not enough, and further research on the relation of ST2 levels with different clinical and laboratory parameters in heart recipients is necessary. 

List of reports on reactor safety research by BMFT, USNRC, EPRI and JSTA. Period under review: 1st January until 31st March 1978

International Nuclear Information System (INIS)

1978-05-01

This list reviews reports from the Federal Republic of Germany, from the United States of America and from Japan concerning special problems in the field of Reactor Safety Research. According to the cooperation of the Bundesminister fuer Forschung und Technologie (BMFT) with the United States Regulatory Commisssion (USNRC), the Electric Power Research Institute (EPRI), and the Japan Science and Technology Agency (JSTA) these reports are available in the Gesellschaft fuer Reaktorsicherheit. The list pursues the following order: Country of origin, problem area concerned, according to the Reactor Safety Research Program of BMFT, reporting organisation. The list of reports appears quarterly. Requests for reports should be addressed to GRS, Forschungsbetreuung. Contractual view points have to be considered for the distribution of the reports. (orig.) [de

Knowledge Globalization within and across the People's Republic of China and the United States: A Cross-National Study of Internationalization of Educational Research in the Early 21st Century

Science.gov (United States)

Tierney, Robert J.; Kan, Wei

2016-01-01

The study examines globalization within and across China and the United States in conjunction with a portrayal of the nature of the scholarly endeavors over the past 10 years in the two preeminent educational research journals of these countries. By extensive analyses of topics, methodology, and citations the research clarifies the global and…

1st IAEA research co-ordination meeting on charge exchange cross section data for fusion plasma studies. Summary report

International Nuclear Information System (INIS)

Janev, R.K.

1999-02-01

A brief description of the proceedings and the conclusions of the 1st Research Coordination Meeting on 'Charge Exchange Cross Section Data for Fusion Plasma Studies', held on September 24-25, 1999, at the IAEA Headquarters in Vienna, Austria, is provided. The conclusions of the Meeting regarding the data collection, assessment and generation priorities are also included in the report. (author)

Key considerations for the success of Medical Education Research and Innovation units in Canada: unit director perceptions.

Science.gov (United States)

Varpio, Lara; Bidlake, Erin; Humphrey-Murto, Sue; Sutherland, Stephanie; Hamstra, Stanley J

2014-08-01

Growth in the field of medical education is evidenced by the proliferation of units dedicated to advancing Medical Education Research and Innovation (MERI). While a review of the literature discovered narrative accounts of MERI unit development, we found no systematic examinations of the dimensions of and structures that facilitate the success of these units. We conducted qualitative interviews with the directors of 12 MERI units across Canada. Data were analyzed using qualitative description (Sandelowski in Res Nurs Health 23:334-340, 2000). Final analysis drew on Bourdieu's (Outline of a theory of practice. Cambridge University Press, Cambridge, 1977; Media, culture and society: a critical reader. Sage, London, 1986; Language and symbolic power. Harvard University Press, Cambridge, 1991) concepts of field, habitus, and capital, and more recent research investigating the field of MERI (Albert in Acad Med 79:948-954, 2004; Albert et al. in Adv Health Sci Educ 12:103-115, 2007). When asked about the metrics by which they define their success, directors cited: teaching, faculty mentoring, building collaborations, delivering conference presentations, winning grant funding, and disseminating publications. Analyzed using Bourdieu's concepts, these metrics are discussed as forms of capital that have been legitimized in the MERI field. All directors, with the exception of one, described success as being comprised of elements (capital) at both ends of the service-research spectrum (i.e., Albert's PP-PU structure). Our analysis highlights the forms of habitus (i.e., behaviors, attitudes, demeanors) directors use to negotiate, strategize and position the unit within their local context. These findings may assist institutions in developing a new-or reorganizing an existing-MERI unit. We posit that a better understanding of these complex social structures can help units become savvy participants in the MERI field. With such insight, units can improve their academic output and

Statistics in the 21st century

CERN Document Server

Wells, Martin T; Wells, Martin T

2001-01-01

Exactly what is the state of the art in statistics as we move forward into the 21st century? What promises, what trends does its future hold? Through the reflections of 70 of the world's leading statistical methodologists, researchers, theorists, and practitioners, Statistics in the 21st Century answers those questions. Originally published in the Journal of the American Statistical Association, this collection of vignettes examines our statistical past, comments on our present, and speculates on our future. Although the coverage is broad and the topics diverse, it reveals the essential intell

Statement to the 41st session of the General Conference of the International Atomic Energy Agency 29 September 1997; Statement to the 52nd session of the United Nations General Assembly 12 November 1997

International Nuclear Information System (INIS)

Blix, H.

1997-12-01

The document presents Statement to the 41st Session of the General Conference of the International Atomic Energy Agency and Statement to the 52nd Session of the United Nations General Assembly made at the 40th anniversary of the IAEA

Highlight: Research Chair unites four West African universities in ...

International Development Research Centre (IDRC) Digital Library (Canada)

2016-04-14

Apr 14, 2016 ... Local and regional experts including researchers, consultants, and academics convened in Cotonou, Benin, on February 26, 2015 to launch a Research Chair on EcoHealth. The Chair unites four West African universities that have pledged to reduce air pollution and non-communicable respiratory ...

The Prospect of Neutron Scattering In the 21st Century: A Powerful Tool for Materials Research

Directory of Open Access Journals (Sweden)

E. Kartini

2007-07-01

Full Text Available Over the last 60 years research reactors (RRs have played an important role in technological and socio-economical development of mankind, such as radioisotope production for medicine, industry, research and education. Neutron scattering has been widely used for research and development in materials science. The prospect of neutron scattering as a powerful tool for materials research is increasing in the 21st century. This can be seen from the investment of several new neutron sources all over the world such as the Spallation Neutron Source (SNS in USA, the Japan Proton Accelerator Complex (JPARC in Japan, the new OPAL Reactor in Australia, and some upgrading to the existing sources at ISIS, Rutherford Appleton Laboratory, UK; Institute of Laue Langevin (ILL in Grenoble, France and Berlin Reactor, Germany. Developing countries with moderate flux research reactor have also been involved in this technique, such as India, Malaysia and Indonesia. The Siwabessy Multipurpose Reactor in Serpong, Indonesia that also produces thermal neutron has contributed to the research and development in the Asia Pacific Region. However, the international joint research among those countries plays an important role on optimizing the results.

The Prospect of Neutron Scattering in The 21st Century : A Powerful Tool For Materials Research

International Nuclear Information System (INIS)

E-Kartini

2007-01-01

Over the last 60 years research reactors (RRs) have played an important role in technological and socio-economical development of mankind, such as radioisotope production for medicine, industry, research and education. Neutron scattering has been widely used for research and development in materials science. The prospect of neutron scattering as a powerful tool for materials research is increasing in the 21 st century. This can be seen from the investment of several new neutron sources all over the world such as the Spallation Neutron Source (SNS) in USA, the Japan Proton Accelerator Complex (JPARC) in Japan, the new OPAL Reactor in Australia, and some upgrading to the existing sources at ISIS, Rutherford Appleton Laboratory, UK; Institute of Laue Langevin (ILL) in Grenoble, France and Berlin Reactor, Germany. Developing countries with moderate flux research reactor have also been involved in this technique, such as India, Malaysia and Indonesia The Siwabessy Multipurpose Reactor in Serpong, Indonesia that also produces thermal neutron has contributed to the research and development in the Asia Pacific Region. However,the international joint research among those countries plays an important role on optimizing the results. (author)

St. Louis encephalitis virus possibly transmitted through blood transfusion-Arizona, 2015.

Science.gov (United States)

Venkat, Heather; Adams, Laura; Sunenshine, Rebecca; Krow-Lucal, Elisabeth; Levy, Craig; Kafenbaum, Tammy; Sylvester, Tammy; Smith, Kirk; Townsend, John; Dosmann, Melissa; Kamel, Hany; Patron, Roberto; Kuehnert, Matthew; Annambhotla, Pallavi; Basavaraju, Sridhar V; Rabe, Ingrid B

2017-12-01

St. Louis encephalitis virus is a mosquito-borne flavivirus that infrequently causes epidemic central nervous system infections. In the United States, blood donors are not screened for St. Louis encephalitis virus infection, and transmission through blood transfusion has not been reported. During September 2015, St. Louis encephalitis virus infection was confirmed in an Arizona kidney transplant recipient. An investigation was initiated to determine the infection source. The patient was interviewed, and medical records were reviewed. To determine the likelihood of mosquito-borne infection, mosquito surveillance data collected at patient and blood donor residences in timeframes consistent with their possible exposure periods were reviewed. To investigate other routes of exposure, organ and blood donor and recipient specimens were obtained and tested for evidence of St. Louis encephalitis virus infection. The patient presented with symptoms of central nervous system infection. Recent St. Louis encephalitis virus infection was serologically confirmed. The organ donor and three other organ recipients showed no laboratory or clinical evidence of St. Louis encephalitis virus infection. Among four donors of blood products received by the patient via transfusion, one donor had a serologically confirmed, recent St. Louis encephalitis virus infection. Exposure to an infected mosquito was unlikely based on the patient's minimal outdoor exposure. In addition, no St. Louis encephalitis virus-infected mosquito pools were identified around the patient's residence. This investigation provides evidence of the first reported possible case of St. Louis encephalitis virus transmission through blood product transfusion. Health care providers and public health professionals should maintain heightened awareness for St. Louis encephalitis virus transmission through blood transfusion in settings where outbreaks are identified. © 2017 AABB.

Research and photovoltaic industry at the United States

International Nuclear Information System (INIS)

Lerouge, Ch.; Herino, R.; Delville, R.; Allegre, R.

2006-06-01

For a big country as the United States, the solar energy can be a solution for the air quality improvement, the greenhouse gases fight and the reduction of the dependence to the imported petroleum and also for the economic growth by the increase of the employment in the solar industry sector. This document takes stock on the photovoltaic in the United States in the industrial and research domains. The american photovoltaic industry is the third behind the Japan and the Germany. (A.L.B.)

Coordinated Research Projects of the IAEA Atomic and Molecular Data Unit

Science.gov (United States)

Braams, B. J.; Chung, H.-K.

2011-05-01

The IAEA Atomic and Molecular Data Unit is dedicated to the provision of databases for atomic, molecular and plasma-material interaction (AM/PMI) data that are relevant for nuclear fusion research. IAEA Coordinated Research Projects (CRPs) are the principal mechanism by which the Unit encourages data evaluation and the production of new data. Ongoing and planned CRPs on AM/PMI data are briefly described here.

Coordinated Research Projects of the IAEA Atomic and Molecular Data Unit

International Nuclear Information System (INIS)

Braams, B. J.; Chung, H.-K.

2011-01-01

The IAEA Atomic and Molecular Data Unit is dedicated to the provision of databases for atomic, molecular and plasma-material interaction (AM/PMI) data that are relevant for nuclear fusion research. IAEA Coordinated Research Projects (CRPs) are the principal mechanism by which the Unit encourages data evaluation and the production of new data. Ongoing and planned CRPs on AM/PMI data are briefly described here.

A Study of the Climate Change during 21st Century over Peninsular Malaysia Watersheds

Science.gov (United States)

Kavvas, M. L.; Ercan, A.; Ishida, K.; Chen, Z. R.; Jang, S.; Amin, M. Z. M.; Shaaban, A. J.

2016-12-01

15 coarse-resolution (150 - 300 km) climate projections for the 21st century by 3 different coupled land-atmosphere-ocean GCMs (ECHAM5 of the Max Planck Institute of Meteorology of Germany, CCSM3 of the National Center for Atmospheric Research (NCAR) of the United States, and MRI-CGCM2.3.2 of the Meteorological Research Institute of Japan) under 4 different greenhouse gas emission scenarios (B1, A1B, A2, A1FI) were dynamically downscaled at hourly intervals by a regional hydro-climate model of Peninsular Malaysia (RegHCM-PM) that consisted of Regional Atmospheric Model MM5 that was coupled with WEHY watershed hydrology model over Peninsular Malaysia (PM), at the scale of the hillslopes of 13 selected watersheds (Batu Pahat, Johor, Muda, Kelang, Kelantan, Linggi, Muar, Pahang, Perak, Selangor, Dungun, Kemaman and Kuantan) and 12 selected intervening coastal regions in order to assess the impact of climate change on the climate conditions at the selected watersheds and coastal regions of PM. From the downscaled climate projections it can be concluded that the mean annual precipitation gradually increases toward the end of the 21st century over each of the 13 watersheds and the 12 coastal regions. The basin-average mean annual temperature increases in the range of 2.50C - 2.950C over PM during the 2010 -2100 period when compared to the 1970-2000 historical period. The ensemble average basin-average annual potential evapotranspiration increases gradually throughout the 21st century over all watersheds.

PREFACE: 15th Latin American Workshop on Plasma Physics (LAWPP 2014) and 21st IAEA TM on Research Using Small Fusion Devices (RUSFD)

Science.gov (United States)

Iván Vargas-Blanco, V.; Herrera-Velázquez, J. Julio E.

2015-03-01

Written contributions from participants of the Joint 15th Latin American Workshop on Plasma Physics (LAWPP 2014) - 21st IAEA Technical Meeting on Research Using Small Fusion Devices (21st IAEA TM RUSFD). The International Advisory Committees of the 15th Latin American Workshop on Plasma Physics (LAWPP 2014) and the 21st IAEA TM on Research Using Small Fusion Devices (RUSFD), agreed to carry out together this Joint LAWPP 2014 - 21st RUSFD in San José, Costa Rica, on 27-31 January 2014. The Joint LAWPP 2014 - 21st RUSFD meeting, organized by the Instituto Tecnológico de Costa Rica, Universidad Nacional de Costa Rica, and Ad Astra Rocket Company in collaboration with the International Atomic Energy Agency (IAEA). The Latin American Workshop on Plasma Physics (LAWPP) is a series of events which has been held periodically since 1982, with the purpose of providing a forum in which the research of the Latin American plasma physics community can be displayed, as well as fostering collaborations among plasma scientists within the region and with researchers from the rest of the world. Recognized plasma scientists from developed countries are specially invited to the meeting to present the state of the art on several "hot" topics related to plasma physics. It is an open meeting, with an International Advisory Committee, in which the working language is English. It was firstly held in 1982 in Cambuquira, Brazil, followed by workshops in Medellín, Colombia (1985), Santiago de Chile, Chile (1988), Buenos Aires, Argentina (1990), Mexico City, Mexico (1992), Foz do Iguaçu, Brazil (1994, combined with the International Congress on Plasma Physics (ICPP)), Caracas, Venezuela (1997), Tandil, Argentina (1998), La Serena, Chile (2000), Sao Pedro, Brazil (2003), Mexico City, Mexico (2005), Caracas, Venezuela (2007), Santiago de Chile, Chile (2010, combined with the ICPP) and Mar de Plata, Argentina (2011). The 21st IAEA TM on Research Using Small Fusion Devices is an ideal forum for

Strategic Engagement in Global S&T: Opportunities for Defense Research

Science.gov (United States)

2014-01-01

ameliorating global chal- lenges, such as natural and engineered disasters (e.g., Fukushima Daiichi nuclear disaster ) and pandemic disease outbreaks (e.g...importance of both maintaining awareness of global S&T advances and increasing engagement with other parts of the U.S. government, industry, academia...perspectives on the following themes: mission, mechanisms for technology awareness , relationship building, enterprise coordination and connectivity, and

PREFACE: 1st International Conference on Mechanical Engineering Research 2011 (ICMER2011)

Science.gov (United States)

Abu Bakar, Rosli

2012-09-01

The year 2010 represented a significant milestone in the history of the Mechanical Engineering community with the organization of the first and second national level conferences (National Conference in Mechanical Engineering for Research, 1st and 2nd NCMER) at Universiti Malaysia Pahang on 26-27 May and 3-4 December 2010. The conferences attracted a large number of delegates from different premier academic and research institutions in the country to participate and share their research experiences at the conference. The International Conference on Mechanical Engineering Research (ICMER 2011) followed on from the first and second conferences due to good support from researchers. The ICMER 2011 is a good platform for researchers and postgraduate students to present their latest finding in research. The conference covers a wide range of topics including the internal combustion engine, machining processes, heat and mass transfer, fuel, biomechanical analysis, aerodynamic analysis, thermal comfort, computational techniques, design and simulation, automotive transmission, optimization techniques, hybrid electric vehicles, engine vibration, heat exchangers, finite element analysis, computational fluid dynamics, green energy, vehicle dynamics renewable energy, combustion, design, product development, advanced experimentation techniques, to name but a few. The international conference has helped to bridge the gap between researchers working at different institutions and in different countries to share their knowledge and has helped to motivate young scientists with their research. This has also given some clear direction for further research from the deliberations of the conference. Several people have contributed in different ways to the success of the conference. We thank the keynote speakers and all authors of the contributed papers, for the cooperation rendered to us in the publication of the CD conference proceedings. In particular, we would like to place on record our

Projections of Climate Change over China for the 21st Century

Institute of Scientific and Technical Information of China (English)

LUO Yong; ZHAO Zongci; XU Ying; GAO Xuejie; DING Yihui

2005-01-01

The projections of climate changes in China for the 21st century by about 40 climate scenarios and multi-model ensembles have been investigated in this research. All the models with the different scenarios project a warming of 1.2℃ to 9.2℃ in China by the end of 21st century. Most of the projections point show the increasing of precipitation in China for the 21st century.

The new Facilities Management contract at CERN from 1st July 2002

CERN Document Server

Mauro Nonis

2002-01-01

Within the ST Division, all the Facilities Management activities have been under the ST/TFM group responsibility until the 30th June 2002, who has performed them using around 20 industrial support contracts. Starting from the 1st July 2002 a new unit, ST/FM, will take over these activities that will be unified into one single contract that has been adjudicated to the company Facilities Management Network SA. This contract will be in charge of the maintenance and minor works on tertiary installations (i.e. all structures and installations that have no direct relation to the running of the accelerators) for the following trades: - Technical: heating, ventilation, air conditioning, plumbing, electricity, civil engineering (painting, roofing, glazing, blinds, fencing, masonry etc.), passenger and goods lifts, automatic and powered doors, kitchen equipment, roads, signs, keys and locks, office furniture, - Services: waste collection, security, green areas, cleaning and sanitary supplies, disinfection, rodent cont...

THE NEW FACILITIES MANAGEMENT CONTRACT AT CERN FROM 1st JULY 2002

CERN Multimedia

Mauro Nonis

2002-01-01

Within the ST Division, all the Facilities Management activities have been under the ST/TFM group responsibility until the 30th June 2002, who has performed them using around 20 industrial support contracts. Starting from the 1st July 2002 a new unit, ST/FM, will take over these activities that will be unified into one single contract that has been adjudicated to the company Facilities Management Network SA. This contract will be in charge of the maintenance and minor works on tertiary installations (i.e. all structures and installations that have no direct relation to the running of the accelerators) for the following trades: Technical: heating, ventilation, air conditioning, plumbing, electricity, civil engineering (painting, roofing, glazing, blinds, fencing, masonry etc.), passenger and goods lifts, automatic and powered doors, kitchen equipment, roads, signs, keys and locks, office furniture, Services: waste collection, security, green areas, cleaning and sanitary supplies, disinfection, rodent contro...

Research Center for Optical Physics: Education and Technology for the 21st Century

Science.gov (United States)

2003-01-01

During the past eleven years since its inception, RCOP has excelled in its two primary goals: 1) training of the scientists and engineers needed for the twenty-first century with special emphasis on underrepresented citizens and 2) research and technological development in areas of relevance to NASA. In the category of research training, as of May 2003, RCOP produced 36 Bachelors degrees, 25 Masters degrees, and 13 Doctoral degrees. Of these, all 36 Bachelors degrees, 16 of the Masters degrees and 9 of the Doctoral degrees were awarded to African Americans. Four of the Doctoral graduates and one of the Masters graduates are working at NASA Field Centers. RCOP has also provided research experiences to 130 undergraduate students and 22 high school students through a number of outreach programs held during the summer and the academic year. RCOP has also been crucial to the development of the Ph.D. program in physics at Hampton University by providing high quality research training and technical electives required for a Doctoral degree in physics. RCOP has also excelled in research and technological development. Since 1992, RCOP researchers have leveraged over 8 million dollars in additional research funding, published 152 papers in refereed journals and proceedings, and given 125 presentations at refereed international conferences in the United States and eight other countries. RCOP also developed numerous collaborations with other research centers, universities and industries. In recognition of this outstanding work, RCOP is the first research center in the United States invited to join the Joint Open Laboratory for Laser Crystals and Precise Laser Systems headed by Dr. Alexander Kaminiskii of the Russian Academy of Sciences.

The care unit in nursing home research: evidence in support of a definition.

Science.gov (United States)

Estabrooks, Carole A; Morgan, Debra G; Squires, Janet E; Boström, Anne-Marie; Slaughter, Susan E; Cummings, Greta G; Norton, Peter G

2011-04-14

Defining what constitutes a resident care unit in nursing home research is both a conceptual and practical challenge. The aim of this paper is to provide evidence in support of a definition of care unit in nursing homes by demonstrating: (1) its feasibility for use in data collection, (2) the acceptability of aggregating individual responses to the unit level, and (3) the benefit of including unit level data in explanatory models. An observational study design was used. Research (project) managers, healthcare aides, care managers, nursing home administrators and directors of care from thirty-six nursing homes in the Canadian prairie provinces of Alberta, Saskatchewan and Manitoba provided data for the study. A definition of care unit was developed and applied in data collection and analyses. A debriefing session was held with research managers to investigate their experiences with using the care unit definition. In addition, survey responses from 1258 healthcare aides in 25 of the 36 nursing homes in the study, that had more than one care unit, were analyzed using a multi-level modeling approach. Trained field workers administered the Alberta Context Tool (ACT), a 58-item self-report survey reflecting 10 organizational context concepts, to healthcare aides using computer assisted personal interviews. To assess the appropriateness of obtaining unit level scores, we assessed aggregation statistics (ICC(1), ICC(2), η², and ω²), and to assess the value of using the definition of unit in explanatory models, we performed multi-level modeling. In 10 of the 36 nursing homes, the care unit definition developed was used to align the survey data (for analytic purposes) to specific care units as designated by our definition, from that reported by the facility administrator. The aggregation statistics supported aggregating the healthcare aide responses on the ACT to the realigned unit level. Findings from the multi-level modeling further supported unit level aggregation. A

Use of a dissolved-gas measurement system for reducing the dissolved oxygen at St. Lucie Unit 2

International Nuclear Information System (INIS)

Snyder, D.T.; Coit, R.L.

1993-02-01

When the dissolved oxygen in the condensate at St. Lucie Unit 2 could not be reduced below the administrative limit of 10 ppB, EPRI cooperated with Florida Power and Light to find the cause and develop remedies. Two problems were identified with the assistance of a dissolved gas measurement system (DGMS) that can detect leaks into condensate when used with argon blanketing. Drain piping from the air ejection system had flooded which decreased its performance, and leaks were found at a strainer flange and a couple expansion joints. Initially the dissolved oxygen content was reduced to about 9 ppB; owever, the dissolved oxygen from Condenser A was consistently higher than that from condenser B. Injection of about 0.4 cubic per minute (CFM) of argon above the hotwell considerably improved the ventilation of Condenser A, reducing the dissolved oxygen about 30% to about 6 ppB. The use of nitrogen was equally effective. While inert gas injection is helpful, it may be better to have separate air ejectors for each condenser. Several recommendations for improving oxygen removal are given

ST product characteristics and relationships with perceptions and behaviors among rural adolescent males: a qualitative study.

Science.gov (United States)

Couch, Elizabeth T; Darius, Ellen F; Walsh, Margaret M; Chaffee, Benjamin W

2017-12-01

Although smoking declines in the United States, the prevalence of male adolescent smokeless tobacco (ST; moist snuff and chewing tobacco) use remains unchanged. ST product characteristics, such as flavoring, packaging, and branding, could influence adolescents' ST initiation and continued use. This qualitative study examines the potential role of product characteristics in shaping ST-related perceptions and behaviors among rural adolescent males. Semi-structured individual interviews were conducted at three California rural high schools. ST users were asked about their experiences and perceptions related to product characteristics. Interviews were transcribed, coded, and analyzed using a general inductive approach. Participants associated flavored ST with appealing non-tobacco products, such as chewing gum and alcohol. Availability of different varieties and flavors stimulated interest and curiosity in sampling or switching between ST products. Time-limited promotional flavors and packaging also enhanced product appeal. Adolescent ST users preferred certain brands based on perceived brand features and perceived nicotine content, associating higher-strength brands as better suited for experienced ST users. Brand preferences frequently reflected perceived ST brand popularity within peer groups. Based on these observations, potential ST regulation and health education campaigns to address misconceptions about ST characteristics could influence adolescents' ST-related perceptions and reduce ST use among this vulnerable population. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Multidimensional Space-Time Methodology for Development of Planetary and Space Sciences, S-T Data Management and S-T Computational Tomography

Science.gov (United States)

Andonov, Zdravko

This R&D represent innovative multidimensional 6D-N(6n)D Space-Time (S-T) Methodology, 6D-6nD Coordinate Systems, 6D Equations, new 6D strategy and technology for development of Planetary Space Sciences, S-T Data Management and S-T Computational To-mography. . . The Methodology is actual for brain new RS Microwaves' Satellites and Compu-tational Tomography Systems development, aimed to defense sustainable Earth, Moon, & Sun System evolution. Especially, extremely important are innovations for monitoring and protec-tion of strategic threelateral system H-OH-H2O Hydrogen, Hydroxyl and Water), correspond-ing to RS VHRS (Very High Resolution Systems) of 1.420-1.657-22.089GHz microwaves. . . One of the Greatest Paradox and Challenge of World Science is the "transformation" of J. L. Lagrange 4D Space-Time (S-T) System to H. Minkovski 4D S-T System (O-X,Y,Z,icT) for Einstein's "Theory of Relativity". As a global result: -In contemporary Advanced Space Sciences there is not real adequate 4D-6D Space-Time Coordinate System and 6D Advanced Cosmos Strategy & Methodology for Multidimensional and Multitemporal Space-Time Data Management and Tomography. . . That's one of the top actual S-T Problems. Simple and optimal nD S-T Methodology discovery is extremely important for all Universities' Space Sci-ences' Education Programs, for advances in space research and especially -for all young Space Scientists R&D!... The top ten 21-Century Challenges ahead of Planetary and Space Sciences, Space Data Management and Computational Space Tomography, important for successfully de-velopment of Young Scientist Generations, are following: 1. R&D of W. R. Hamilton General Idea for transformation all Space Sciences to Time Sciences, beginning with 6D Eukonal for 6D anisotropic mediums & velocities. Development of IERS Earth & Space Systems (VLBI; LLR; GPS; SLR; DORIS Etc.) for Planetary-Space Data Management & Computational Planetary & Space Tomography. 2. R&D of S. W. Hawking Paradigm for 2D

Science Policy Research Unit annual report 1984/1985

Energy Technology Data Exchange (ETDEWEB)

1984-01-01

The report covers the principal research programmes of the Unit, and also describes its graduate and undergraduate teaching, (listing subjects of postgraduate research) and library services. A list of 1984 published papers and staff is presented. The principle research programmes include: the setting up of the Designated Research Centre on Science, Technology and Energy Policy in British Economic Development; policy for technology and industrial innovation in industrialised countries; energy economics, technology and policy (with a sub-section on coal); European science and industrial policy; science policy and research evaluation; technical change and employment opportunities in the UK economy; new technology, manpower and skills; technology and social change; science and technology policy in developing countries; military technology and arms limitation. Short-term projects and consultancy are also covered.

Updating Photonuclear Data Library and Generating a Reference Database for Photon Strength Functions. 1st Research Coordination Meeting. Summary Report

International Nuclear Information System (INIS)

Goriely, S.; Dimitriou, P.

2016-07-01

A summary is given of the 1 st Research Coordination Meeting of the new IAEA Co-ordinated Research Project (CRP) on Updating the Photonuclear Data Library and Generating a Reference Database for Photon Strength Functions. Participants presented their work, reviewed the current status of the field with regards to measurements, theoretical models and evaluations, discussed the scope of the work to be undertaken and agreed on a list of priorities and task assignments necessary to achieve the goals of the CRP. A summary of the presentations and discussions is presented in this report. (author)

Fort St. Vrain circulator operating experience

International Nuclear Information System (INIS)

Brey, H.L.

1988-01-01

Fort St. Vrain, on the system of Public Service Company of Colorado, is the only high-temperature gas-cooled power reactor in the United States. Four helium circulators are utilized in this plant to transfer heat from the reactor to the steam generators. These unique machines have a single stage axial flow helium compressor driven by a single stage steam turbine. A single stage water driven (pelton wheel) turbine is the back-up drive utilizing either feed water, condensate, or fire water as the driving fluid. Developmental testing of the circulators was accomplished prior to installation into Fort St. Vrain. A combined machine operating history of approximately 250,000 hours has shown these machines to be of conservative design and proven mechanical integrity. However, many problems have been encountered in operating the complex auxiliaries which are necessary for successful circulator and plant operation. It has been 15 years since initial installation of the circulators occurred at Fort St. Vrain. During this time, a number of significant issues had to be resolved dealing specifically with machine performance. These events include cavitation damage of the pelton wheels during the initial plant hot functional testing, cracks in the water turbine buckets and cervic coupling, static shutdown seal bellows failure, and, most recently, degradation of components within the steam drive assembly. Unreliable operation particularly with the circulator auxiliaries has been a focus of attention by Public Service Company of Colorado. Actions to replace or significantly modify the existing circulators and their auxiliaries are currently awaiting decisions concerning the long-term future of the Fort St. Vrain plant. (author). 10 refs, 7 figs, 2 tabs

Fort St. Vrain circulator operating experience

Energy Technology Data Exchange (ETDEWEB)

Brey, H. L.

1988-08-15

Fort St. Vrain, on the system of Public Service Company of Colorado, is the only high-temperature gas-cooled power reactor in the United States. Four helium circulators are utilized in this plant to transfer heat from the reactor to the steam generators. These unique machines have a single stage axial flow helium compressor driven by a single stage steam turbine. A single stage water driven (pelton wheel) turbine is the back-up drive utilizing either feed water, condensate, or fire water as the driving fluid. Developmental testing of the circulators was accomplished prior to installation into Fort St. Vrain. A combined machine operating history of approximately 250,000 hours has shown these machines to be of conservative design and proven mechanical integrity. However, many problems have been encountered in operating the complex auxiliaries which are necessary for successful circulator and plant operation. It has been 15 years since initial installation of the circulators occurred at Fort St. Vrain. During this time, a number of significant issues had to be resolved dealing specifically with machine performance. These events include cavitation damage of the pelton wheels during the initial plant hot functional testing, cracks in the water turbine buckets and cervic coupling, static shutdown seal bellows failure, and, most recently, degradation of components within the steam drive assembly. Unreliable operation particularly with the circulator auxiliaries has been a focus of attention by Public Service Company of Colorado. Actions to replace or significantly modify the existing circulators and their auxiliaries are currently awaiting decisions concerning the long-term future of the Fort St. Vrain plant. (author). 10 refs, 7 figs, 2 tabs.

75 FR 36062 - Notice of Enforcement Policy Symposium on Combating Counterfeiting in the 21st Century

Science.gov (United States)

2010-06-24

... second panel on criminal procedure will involve a discussion of enforcement policy involving the... Enforcement Policy Symposium on Combating Counterfeiting in the 21st Century AGENCY: United States Patent and... United States Government enforcement policy regarding counterfeit goods involving health and safety...

Conducting qualitative research within Clinical Trials Units: avoiding potential pitfalls.

Science.gov (United States)

Cooper, Cindy; O'Cathain, Alicia; Hind, Danny; Adamson, Joy; Lawton, Julia; Baird, Wendy

2014-07-01

The value of using qualitative research within or alongside randomised controlled trials (RCTs) is becoming more widely accepted. Qualitative research may be conducted concurrently with pilot or full RCTs to understand the feasibility and acceptability of the interventions being tested, or to improve trial conduct. Clinical Trials Units (CTUs) in the United Kingdom (UK) manage large numbers of RCTs and, increasingly, manage the qualitative research or collaborate with qualitative researchers external to the CTU. CTUs are beginning to explicitly manage the process, for example, through the use of standard operating procedures for designing and implementing qualitative research with trials. We reviewed the experiences of two UK Clinical Research Collaboration (UKCRC) registered CTUs of conducting qualitative research concurrently with RCTs. Drawing on experiences gained from 15 studies, we identify the potential for the qualitative research to undermine the successful completion or scientific integrity of RCTs. We show that potential problems can arise from feedback of interim or final qualitative findings to members of the trial team or beyond, in particular reporting qualitative findings whilst the trial is on-going. The problems include: We make recommendations for improving the management of qualitative research within CTUs. Copyright © 2014. Published by Elsevier Inc.

United States Domestic Research Reactor Infrastructure TRIGA Reactor Fuel Support

International Nuclear Information System (INIS)

Morrell, Douglas

2011-01-01

The United State Domestic Research Reactor Infrastructure Program at the Idaho National Laboratory manages and provides project management, technical, quality engineering, quality inspection and nuclear material support for the United States Department of Energy sponsored University Reactor Fuels Program. This program provides fresh, unirradiated nuclear fuel to Domestic University Research Reactor Facilities and is responsible for the return of the DOE-owned, irradiated nuclear fuel over the life of the program. This presentation will introduce the program management team, the universities supported by the program, the status of the program and focus on the return process of irradiated nuclear fuel for long term storage at DOE managed receipt facilities. It will include lessons learned from research reactor facilities that have successfully shipped spent fuel elements to DOE receipt facilities.

The NEIL Memory Research Unit: psychosocial, biological, physiological and lifestyle factors associated with healthy ageing: study protocol.

Science.gov (United States)

Hannigan, Caoimhe; Coen, Robert F; Lawlor, Brian A; Robertson, Ian H; Brennan, Sabina

2015-01-01

Population ageing is a global phenomenon that has characterised demographic trends during the 20th and 21st century. The rapid growth in the proportion of older adults in the population, and resultant increase in the incidence of age-related cognitive decline, dementia and Alzheimer's disease, brings significant social, economic and healthcare challenges. Decline in cognitive abilities represents the most profound threat to active and healthy ageing. Current evidence suggests that a significant proportion of cases of age-related cognitive decline and dementia may be preventable through the modification of risk factors including education, depressive symptomology, physical activity, social engagement and participation in cognitively stimulating activities. The NEIL Memory Research Unit cohort study was established to investigate factors related to brain health and the maintenance of cognitive function. A cohort of 1000 normally ageing adults aged 50 years and over are being recruited to participate in comprehensive assessments at baseline, and at follow-up once every 2 years. The assessment protocol comprises a comprehensive neuropsychological battery, some basic physical measures, psychosocial scales, questionnaire measures related to a range of health, lifestyle and behavioural factors, and a measure of resting state activity using electroencephalography (EEG). The NEIL Memory Research Unit cohort study will address key questions about brain health and cognitive ageing in the population aged 50+, with a particular emphasis on the influence of potentially modifiable factors on cognitive outcomes. Analyses will be conducted with a focus on factors involved in the maintenance of cognitive function among older adults, and therefore will have the potential to contribute significant knowledge related to key questions within the field of cognitive ageing, and to inform the development of public health interventions aimed at preventing cognitive decline and promoting

First-principles study of hydrogen-bonded molecular conductor κ -H3(Cat-EDT-TTF/ST)2

Science.gov (United States)

Tsumuraya, Takao; Seo, Hitoshi; Kato, Reizo; Miyazaki, Tsuyoshi

2015-07-01

We theoretically study hydrogen-bonded molecular conductors synthesized recently, κ -H3(Cat-EDT-TTF) 2 and its diselena analog, κ -H3(Cat-EDT-ST) 2, by first-principles density functional theory calculations. In these crystals, two H(Cat-EDT-TTF/ST) units share a hydrogen atom with a short O-H-O hydrogen bond. The calculated band structure near the Fermi level shows a quasi-two-dimensional character with a rather large interlayer dispersion due to the absence of insulating layers, in contrast with conventional molecular conductors. We discuss effective low-energy models based on H(Cat-EDT-TTF/ST) units and its dimers, respectively, where the microscopic character of the orbitals composing them are analyzed. Furthermore, we find a stable structure which is different from the experimentally determined structure, where the shared hydrogen atom becomes localized to one of the oxygen atoms, in which charge disproportionation between the two types of H(Cat-EDT-TTF) units is associated. The calculated potential energy surface for the H atom is very shallow near the minimum points; therefore the probability of the H atom can be delocalized between the two O atoms.

Elementary Science Instruction: Examining a Virtual Environment for Evidence of Learning, Engagement, and 21st Century Competencies

Directory of Open Access Journals (Sweden)

Terry K. Smith

2014-03-01

Full Text Available This mixed methods study examined the effectiveness of a virtual world curriculum for teaching elementary students complex science concepts and skills. Data were collected using pre- and post-content tests and a student survey of engaged learning, An additional survey collected teacher observations of 21st century competencies conducive to learning. The study involved a five-day intervention of fifteen 4th grade students in a small Midwestern school using a virtual science computer game from Arizona State University. Thirty elementary teachers from Australia, England, and the United States were surveyed on classroom observations of their elementary students working in the virtual world environment. Research questions guiding the virtual learning study were: (1 do pre- and post-content tests show significant learning in the virtual environment; (2 are students academically engaged during the learning process; and (3 are students actively demonstrating relevant 21st century competencies. The study supports prior research in game-based learning showing measureable learning results, highly engaged, motivated students, and observations of student behaviors conducive to learning science in school, namely collaboration, problem solving, critical thinking/inquiry, global awareness, and technology use.

Stāstu stāstīšanas izmantošana lasīšanas veicināšanas pasākumos

OpenAIRE

Mežjāne, Signe

2014-01-01

Bakalaura darba mērķis ir noskaidrot, vai stāstu stāstīšana ir efektīvs lasīšanas veicināšanas paņēmiens bērniem. Pētījuma problēma ir mūsdienu bērnu nevēlēšanās lasīt, lasīšanu varētu veicināt stāstu stāstīšana bibliotēkās. Darbā tiek analizēts stāstu stāstīšanas process atbilstoši bērnu vecumposmam, izmantojot dažādus runas stilus. Teorētiskā bāze ir balstīta uz Lasītāja reakcijas kritikas teoriju un Runas darbības teoriju. Galvenie pētījuma uzdevumi ir noskaidrot, vai Latvijas bibliotē...

75 FR 51945 - Safety Zone; Potomac River, St. Mary's River, St. Inigoes, MD

Science.gov (United States)

2010-08-24

...-AA00 Safety Zone; Potomac River, St. Mary's River, St. Inigoes, MD AGENCY: Coast Guard, DHS. ACTION... of the St. Mary's River, a tributary of the Potomac River. This action is necessary to provide for.... Navy helicopter located near St. Inigoes, Maryland. This safety zone is intended to protect the...

Toxic Hazards Research Unit Annual Report: 1986

Science.gov (United States)

1987-04-01

mediated hemolysis by mercapto compounds. Journal of Applied Toxicology, Volume 6, Number 5, pages 336-370, 1986. Hydrophobic tributyltin ( TBT ...7 ~OF~ AAMRL-TR-87-020 NMRI-87-2 ’~LRES 4 Iq 1986 TOXIC HAZARDS RESEARCH UNIT ANNUAL REPORT WILLIAM E. HOUSTON, Ph.D. RAYMOND S. KUTZMAN, Ph.D...and is approved for publication. FOR THE COMMANDElRi BRUCE 0. STUART, Ph.D. Director, Toxic Hazards Division Harry G. Armstrong Aerospace Medical

Hmong Political Involvement in St. Paul, Minnesota and Fresno, California

Directory of Open Access Journals (Sweden)

Yang Lor

2010-01-01

Full Text Available Over the past several years, Hmong in the United States have gained prominence for their increasing involvement in politics. Most of the attention has understandably focused on Fresno, California and St. Paul, Minnesota, home to the two largest Hmong populations in this country. While the Hmong communities in both cities are similar in size and have made significant political progress as evidenced by the election of Hmong candidates, the Hmong community in St. Paul has made greater inroads in the political realm. In addition to the elections of two Hmong candidates to the Minnesota State Legislature and two to the St. Paul School Board, the Hmong community in St. Paul has been able to engage local and state governments in Minnesotato address issues that affect the Hmong community. Through interviews, census data, and newspaper coverage of political campaigns, I show that Hmong in St. Paul have achieved greaterrepresentation in local and state governments and received greater support from government officials than Hmong in Fresno because Minnesota offers a social, economic, and politicalcontext that is favorable to fostering Hmong political involvement. Compared to Hmong in Fresno, Hmong in St. Paul have higher levels of socioeconomic resources and are more visible given their large size relative to other minority groups. They live in a region with consistently high levels of political participation and have political candidates who devote resources to mobilizing the Hmong community. Moreover, the Hmong vote has been critical to the success of Hmong candidates in St. Paul, an indication of the increasing political clout of the Hmong community there and a major reason why politicians in Minnesota are more willing to respond toissues that affect the Hmong community. Overall, this study highlights the importance of local and regional context in understanding the political incorporation of immigrants.

Rethinking Approaches to Strategic Stability in the 21st Century

Energy Technology Data Exchange (ETDEWEB)

Rose, Brian [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2017-02-01

Lawrence Livermore National Laboratory (LLNL) hosted a two-day conference on rethinking approaches to strategic stability in the 21st century on October 20-21, 2016 in Livermore, CA. The conference was jointly convened by Lawrence Livermore, Los Alamos, and Sandia National Laboratories, and was held in partnership with the United States Department of State’s Bureau of Arms Control, Verification and Compliance. The conference took place at LLNL’s Center for Global Security Research (CGSR) and included a range of representatives from U.S. government, academic, and private institutions, as well as representatives from U.S. allies in Europe and Asia.The following summary covers topics and discussions from each of the panels. It is not intended to capture every point in detail, but seeks to outline the range of views on these complex and inter-related issues while providing a general overview of the panel topics and discussions that took place. The conference was held under the Chatham House rule and does not attribute any remarks to any specific individual or institution. The views reflected in this report do not represent the United States Government, Department of State, or the national laboratories.

“Do the next thing”: an interview with Elizabeth Adams St. Pierre on post-qualitative methodology

Directory of Open Access Journals (Sweden)

Hanna Guttorm

2015-06-01

Full Text Available Professor Elizabeth Adams St. Pierre’s work focuses on critical and poststructural theories of language and the subject and what she has called post qualitative inquiry or post inquiry. She asks what might come after conventional humanist qualitative research methodology. She’s especially interested in the new empiricisms/new materialisms as well as new research practices enabled by the ontological turn. During St. Pierre's visit to the Finnish Educational Research Association (FERA Conference in Oulu in November 2014, we had the opportunity to talk with her about post qualitative research around some questions we had sent her beforehand. We then transcribed, edited, and translated the interview, and published it in the Finnish journal Kasvatus (Education in spring 2015. In this interview St. Pierre talks in the US context, where qualitative methodology is turning—or being pushed to turn—back to positivism with normalized and formalized practices, St. Pierre encourages researchers to constantly question the prevailing truths and the traditions they have learnt too well.

Strategic Research for S&T Planning Should Focus on Key Issues

Institute of Scientific and Technical Information of China (English)

无

2004-01-01

@@ Strategic planning for national and CAS mid- and long-term S&T development should avoid giving equal attention to every aspect of an issue, which can only lead to incremental progress.Instead, importance should be attached to priorities that will result in scientific, technical and engineering breakthroughs, said CAS President Lu Yongxiang, who is also vice-chairman of the national legislature, NPC.

Coal into the 21st century

International Nuclear Information System (INIS)

Beecy, D.J.

1991-01-01

The Plenary lecture to the conference addresses coal technologies with improved environmental performance to serve 21st century needs. The US DoE recognises the need for 'premium' processes for all stages of the fuel cycle. This has led to a research focus on fundamental science and technology

The emerging ST8 methicillin-resistant Staphylococcus aureus clone in the community in Japan: associated infections, genetic diversity, and comparative genomics.

Science.gov (United States)

Iwao, Yasuhisa; Ishii, Rumiko; Tomita, Yusuke; Shibuya, Yasuhiro; Takano, Tomomi; Hung, Wei-Chun; Higuchi, Wataru; Isobe, Hirokazu; Nishiyama, Akihito; Yano, Mio; Matsumoto, Tetsuya; Ogata, Kikuyo; Okubo, Takeshi; Khokhlova, Olga; Ho, Pak-Leung; Yamamoto, Tatsuo

2012-04-01

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has become a major concern worldwide. In the United States, ST8 CA-MRSA with SCCmecIVa (USA300) has been predominant, affecting the entire United States. In this study, we investigated Japanese ST8 CA-MRSA with new SCCmecIVl (designated ST8 CA-MRSA/J), which has emerged in Japan since 2003. Regarding community spread and infections, ST8 CA-MRSA/J spread in 16.2-34.4% as a major genotype in the community in Japan, and was associated with skin and soft tissue infections (SSTIs), colitis, and invasive infections (sepsis, epidural abscesses, and necrotizing pneumonia), including influenza prodrome cases and athlete infections, similar to USA300. It spread to even public transport and Hong Kong through a Japanese family. Regarding genetic diversity, ST8 CA-MRSA/J included ST and spa variants and was classified into at least three pulsed-field gel electrophoresis types, ST8 Jα to γ. Of those, ST8 Jβ was associated with severe invasive infections. As for genomics, ST8 CA-MRSA/J showed high similarities to USA300, but with marked diversity in accessory genes; e.g., ST8 CA-MRSA/J possessed enhanced cytolytic peptide genes of CA-MRSA, but lacked the Panton-Valentine leukocidin phage and arginine catabolic mobile element, unlike USA300. The unique features of ST8 CA-MRSA/J included a novel mosaic SaPI (designated SaPIj50) carrying the toxic shock syndrome toxin-1 gene with high expression; the evolution included salvage (through recombination) of hospital-acquired MRSA virulence. The data suggest that ST8 CA-MRSA/J has become a successful native clone in Japan, in association with not only SSTIs but also severe invasive infections (posing a threat), requiring attention.

Molecular image in biomedical research. Molecular imaging unit of the National Cancer Research Center

International Nuclear Information System (INIS)

Perez Bruzon, J.; Mulero Anhiorte, F.

2010-01-01

This article has two basic objectives. firstly, it will review briefly the most important imaging techniques used in biomedical research indicting the most significant aspects related to their application in the preclinical stage. Secondly, it will present a practical application of these techniques in a pure biomedical research centre (not associated to a clinical facility). Practical aspects such as organisation, equipment, work norms, shielding of the Spanish National Cancer Research Centre (CNIO) Imaging Unit will be shown. This is a pioneering facility in the application of these techniques in research centres without any dependence or any direct relationship with other hospital Nuclear Medicine services. (Author) 7 refs.

21st October 2008 - LHC Inauguration Ceremony family photograph in SM18.

CERN Multimedia

CERN Photo Service

2008-01-01

21st October 2008 - LHC Inauguration Ceremony family photograph in SM18. Front row, from left to right : British Minister of State for Science and Innovation, Lord Drayson of Kensington; Hungarian Minister for Research, Science and Innovation K. Molnar; German Federal Minister of Education and Research A. Schavan; Slovak Deputy Prime Minister and Minister of Education J. Mikolaj; Président de la Confédération suisse P. Couchepin; Directeur général du CERN R. Aymar; Premier Ministre de la République française F. Fillon; Portuguese Minister for Science, Technology and Higher Education J. M. Gago; Ministre belge des PME, des Indépendants, de l'Agriculture et de la Politique scientifique S. Laruelle; Ambassador of Italy to the Office of the United Nations and other international organisations in Geneva G. Caracciolo di Vetri. Second row, from left to right: Czech Deputy Minister of Education, Youth and Sports, responsible for Science and Universities V. Ruzicka; Extraordinatory and Plenipotentiary Ambas...

Systematic Review of the Research on Motor Fitness of 1st-Year Students Attending Polish Institutions of Higher Education

Directory of Open Access Journals (Sweden)

Robert Podstawski

2013-10-01

Full Text Available Aim of the study. To establish: 1 the amount of research on general motor fitness of 1st-year students, conducted at selected Polish institutions of higher education between 1953-2010; 2 the number and kind of motor tests applied in this kind of research as well as the frequency of these tests during the period under study. Material and methods: The material for this research was composed of the publications on motor fitness of the first-year students taking part in specific motor trials applied at Polish tertiary institutions between 1953 - 2010. A diagnostic poll method was used in the research. Results: Fifty-four original research cases conducted in the period under study were observed. Within this period the trials such as: “100m run”, “jump from the run-up”, “grenade throw” and “ shot put” were more popular during the earlier years, while the trials such us: “zig-zag run”, “standing long jump”, and “medicine ball throw” were characteristic of more recent studies. Some of the most popular motor trials were: “standing long jump” – 38 cases, “medicine ball throw” – 30 cases, “zig-zag run” – 28 cases, “shuttle runs” – 9 cases, "short distance runs” – 12 cases, “downward bend from standing position” – 10 cases, and "vertical jump” – 8 cases. Conclusions: 1. Little research concerning the level of physical fitness of first-year students attending Polish tertiary institutions was conducted in the years 1953-2010; 2. The amount of motor fitness research carried out during this period fails to provide constant systematic assessment of the state of the students’ physical condition, which is a result of too large dispersions in time and territory where the measurements were taken; 3. In the motor fitness tests conducted with 1st-year students the determining variable was mainly gender, and only few research cases were found in which general motor fitness was analyzed according to

Cooperative Fish and Wildlife Research Units Program—2017 year in review postcard

Science.gov (United States)

Organ, John F.; Thompson, John D.; Dennerline, Donald E.; Childs, Dawn E.

2018-02-08

This postcard provides details about the Cooperative Fish and Wildlife Research Units Program—2017 Year in Review, U.S. Geological Survey Circular 1438, now available at https://doi.org/10.3133/cir1438. In this report, you will find details about the Cooperative Fish and Wildlife Research Units (CRU) Program relating to its background, fish and wildlife science, students, staffing, vacancies, research funding, outreach and training, science themes, accolades, and professional services. You will see snapshots of CRU projects with information on how results have been or are being applied by cooperators. This is the essence of what we do: science that matters.Throughout the year, keep up with CRU research projects at http://www.coopunits.org.

78 FR 7387 - Advisory Committee on Biotechnology and 21st Century Agriculture; Renewal

Science.gov (United States)

2013-02-01

...;and investigations, committee meetings, agency decisions and rulings, #0;delegations of authority... Biotechnology and 21st Century Agriculture; Renewal AGENCY: Agricultural Research Service, USDA. ACTION: Advisory Committee on Biotechnology and 21st Century Agriculture Renewal. SUMMARY: Notice is hereby given...

Future Directions for Urban Forestry Research in the United States

Science.gov (United States)

John F. Dwyer; David J. Nowak; Gary W. Watson

2002-01-01

Urban forestry research promises to continue to be an integral part of the growth and development of forestry in urban and urbanizing areas of the United States. The future is expected to bring increased emphasis on research in support of the care of trees and other plants, ecological restoration, and comprehensive and adaptive management across the landscape....

A Case Study of 21st Century Skills Programs and Practices

Science.gov (United States)

McLachlan, Kurt

2012-01-01

Skills, such as critical thinking, problem-solving, and innovation are necessary for the 21st Century. The economy and the forums of international business and globalization demand skilled workers. Some schools in the United States are producing such workers, however it is unclear the programs and practices these schools utilize. This study…

Tribal wilderness research needs and issues in the United States and Canada

Science.gov (United States)

Dan McDonald; Tom McDonald; Leo H. McAvoy

2000-01-01

This paper represents a dialogue between tribal wilderness managers and researchers on the primary research needs of tribal wilderness in the United States and Canada. The authors identify a number of research priorities for tribal wildlands. The paper also discusses some major issues and challenges faced by researchers conducting research in areas that are culturally...

Maritime Education and Research to Face the XXI-st Century Challenges in Gdynia Maritime University’s Experience Part I – Maritime Universities Facing Today and Tomorrow’s Challenges

Directory of Open Access Journals (Sweden)

Janusz Mindykowski

2013-12-01

Full Text Available In the paper, divided into two parts, a problem of advancements in maritime education and research facing the 21st century challenges, based on the case study of the Gdynia Maritime University (GMU experience is discussed. Part I is devoted to the main directions of advances in the maritime education and research towards the challenges in a global meaning. In this context, the education and research potential of the Gdynia Maritime University, as one of the world-leading maritime universities, is shortly presented. Part II is dedicated to the Gdynia Maritime University experiencing the 21st century challenges. The GMU’s contribution and good practices concerning the participation in modification of the processes of the IMO STCW 78/2010 convention, adoption of programmes into the international and national qualification frameworks’ standards and procedures, as well as the development of research addressed to a new technological and organizational solution are described and analyzed.

The Twins Study: NASA's First Foray into 21st Century Omics Research

Science.gov (United States)

Kundrot, C. E.; Shelhamer, M.; Scott, G. B. I.

2015-01-01

The full array of 21st century omics-based research methods should be intelligently employed to reduce the health and performance risks that astronauts will be exposed to during exploration missions beyond low Earth Orbit. In March of 2015, US Astronaut Scott Kelly will launch to the International Space Station for a one year mission while his twin brother, Mark Kelly, a retired US Astronaut, remains on the ground. This situation presents an extremely rare flight opportunity to perform an integrated omics-based demonstration pilot study involving identical twin astronauts. A group of 10 principal investigators has been competitively selected, funded, and teamed together to form the Twins Study. A very broad range of biological function are being examined including the genome, epigenome, transcriptome, proteome, metabolome, gut microbiome, immunological response to vaccinations, indicators of atherosclerosis, physiological fluid shifts, and cognition. The plans for the Twins Study and an overview of initial results will be described as well as the technological and ethical issues raised for such spaceflight studies. An anticipated outcome of the Twins Study is that it will place NASA on a trajectory of using omics-based information to develop precision countermeasures for individual astronauts.

Developing nursing research in the United Arab Emirates: a narrative review.

Science.gov (United States)

McCreaddie, M; Kuzemski, D; Griffiths, J; Sojka, E M; Fielding, M; Al Yateem, N; Williams, J J

2018-03-01

This article identified, critically analysed and synthesized the literature on international nursing and midwifery research capacity building and standards. The United Arab Emirates is heavily dependent up on expatriate nurses. Only 4% of nurses working within the country are Emirati. The nation is therefore committed to developing nurses and nursing as a profession. The United Arab Emirates' Nursing and Midwifery Council was formed in 2009 and initially focused on regulation, education and specialization. This review was undertaken to inform the work of the Council's newly established Scientific Research Sub-Committee. A rapid narrative review was conducted using the Cumulative Index of Nursing and Allied Health Literature database, key words, Boolean operators, parameters and a journal-specific search. An inclusion/exclusion criterion was identified. The search provided 332 articles with 45 included in the final review. The literature on nursing research 'standards' and 'capacity building' is diverse and inconsistent across continents and in approaches. Nursing research has evolved to varying degrees across the globe. Nevertheless, irrespective of the locale, there are similar problems encountered in growing research, for example nursing faculty shortage, lack of collaborative research, funding. There are also specific challenges in the Middle East and North Africa region. The review was constrained by time and access. There are specific challenges for the United Arab Emirates. However, the country is well placed to learn from the experiences of colleagues elsewhere. Time and commitment is required to build the solid foundations necessary to ensure robust, sustained growth. Identifying research capacity as both a process and outcome at the outset may also assist. Further, it may be prudent to consider initiating a Gulf Coast Countries' collaborative approach to building research capacity to harness scare resources and create a larger critical mass. © 2017

The next Generation of Exascale-class Systems: the ExaNeSt Project

OpenAIRE

R. Ammendolay; A. Biagioni; P. Cretaro; O. Frezza; F. Lo Cicero; A. Lonardo; M. Martinelli; P. S. Paolucci; E. Pastorelli; F. Simula; P. Vicini; G. Taffoni; J. Goodacree; M. Lujn; J. Navaridas

2017-01-01

The ExaNeSt project started on December 2015 and is funded by EU H2020 research framework (call H2020-FETHPC-2014, n. 671553) to study the adoption of low-cost, Linux-based power-efficient 64-bit ARM processors clusters for Exascale-class systems. The ExaNeSt consortium pools partners with industrial and academic research expertise in storage, interconnects and applications that share a vision of an European Exascale-class supercomputer. Their goal is designing and implementing a physical rac...

1st IAEA research co-ordination meeting on 'plasma-material interaction data for mixed plasma facing materials in fusion reactors'. Summary report

International Nuclear Information System (INIS)

Janev, R.K.; Longhurst, G.

1998-12-01

The proceedings and conclusions of the 1st IAEA Research Co-ordination Meeting on 'Plasma-Material Interaction Data for Mixed Plasma Facing Materials in Fusion Reactors', held on December 19 and 20, 1998 at the IAEA Headquarters in Vienna, are briefly described. This report includes a summary of the presentations made by meeting participants, a review of the data availability and data needs in the areas from the scope of the Co-ordinated Research Project (CRP) on the subject of the meeting, and recommendations regarding the future work within this CRP. (author)

77 FR 26725 - Advisory Committee on Biotechnology and 21st Century Agriculture Meeting

Science.gov (United States)

2012-05-07

...;and investigations, committee meetings, agency decisions and rulings, #0;delegations of authority... Biotechnology and 21st Century Agriculture Meeting AGENCY: Office of the Under Secretary, Research, Education... announces a meeting of the Advisory Committee on Biotechnology and 21st Century Agriculture (AC21). DATES...

Merging formation of FRC and its application to high-beta ST formation

International Nuclear Information System (INIS)

Ono, Y.; Inomoto, M.; Ueda, Y.; Matsuyama, T.; Ohshima, Y.; Katsurai, M.

2001-01-01

Merging formation of field-reversed configuration (FRC) explored not only a new scenario of highly-efficient FRC formation/amplification experiment but also a new boundary research between FRC, spheromak and spherical tokamak (ST). A new finding is that the produced FRC is transformed stably into an ultra-high-β ST by applying external toroidal field B t,ext . The toroidal field was observed to vanish around magnetic axis after the B t,ext application to the FRC, indicating formation of diamagnetic ST. The hollow current profile of FRC was maintained during the equilibrium transition, eliminating a need for the difficult hollow-current-formation process of start-up discharge of high-β ST. The energy-conversion effect of merging transformed the force-free merging spheromaks with paramagnetic current into the FRC with diamagnetic current and the further application of B t,ext did the FRC into the ultra-high-β (>60%)/diamagnetic ST, indicating the close relationship between FRC and ST in second stability. (author)

An example of a United States Nuclear Research Center

International Nuclear Information System (INIS)

Bhattacharyya, S. K.

1999-01-01

Under the likely scenario in which public support for nuclear energy remains low and fossil fuels continue to be abundant and cheap, government supported nuclear research centers must adapt their missions to ensure that they tackle problems of current significance. It will be critical to be multidisciplinary, to generate economic value, and to apply nuclear competencies to current problems. Addressing problems in nuclear safety, D and D, nuclear waste management, nonproliferation, isotope production are a few examples of current needs in the nuclear arena. Argonne's original mission, to develop nuclear reactor technology, was a critical need for the U.S. in 1946. It would be wise to recognize that this mission was a special instance of a more general one--to apply unique human and physical capital to long term, high risk technology development in response to society's needs. International collaboration will enhance the collective chances for success as the world moves into the 21st century

Research of Houjiayao Unit in North China

Science.gov (United States)

Ji, Y.

2012-12-01

"Houjiayao Group" is the standard stratigraphic unit of late Pleistocene in northern China, which was created by Jia Lanpo and Wei Qi during their research on Houjiayao site. Based on the mammal, ancient human fossils and Paleolithic features, "Houjiayao Group" was thought as late Pleistocene sediments. "Houjiayao Group" was defined as late Pleistocene stratigraphic units. However, the problems of the age of "Houjiayao Group", stratigraphic division and other issues, have not yet been well resolved. These issues include: the differences of age-dating results, the unclear comparison between stratigraphic units and regional contrast, the uncertain relationship between "Houjiayao Group" and "Nihewan Layer ", and so on. Houjiayao site which located in the southeast of Houjiayao village in Dongjingji town Yangyuan County, Hebei province of China, is a very important paleolithic site. But some researches show that Houjiayao site is located at the 3th terrace of Liyigou valley and there are many opinions about the age of Houjiayao site, which varies from 20-500 thousand years. Combined with former research results and many research methods, our study was mainly focused on the key problems existing in the study of "Houjiayao Group". Through the use of sequence stratigraphy, chronostratigraphy, biostratigraphy and other theoretical methods, stratigraphic section was studied in the late Pleistocene stratigraphy and sedimentary environment. Through environmental indicators and the age-dating tests, the evolution of ancient geography and environment were identified elementarily. After analyzing informations of this area, geomorphologic investigation and stratum comparation in and around Houjiayao site were done. Houjiayao site is located on the west bank of Liyigou river, which has a tributary named Black Stone River. Two or three layers of volcanic materials were found in this area, those sediments are from a buried paleovolcano in upstream of Black Stone River. The volcanic

78 FR 19632 - Special Local Regulations; St. Thomas Carnival Watersport Activities, Charlotte Amalie Harbor; St...

Science.gov (United States)

2013-04-02

...-AA08 Special Local Regulations; St. Thomas Carnival Watersport Activities, Charlotte Amalie Harbor; St... proposes to establish a special local regulation on the waters of Charlotte Amalie Harbor in St Thomas, USVI during the St. Thomas Carnival Watersport Activities, a high speed boat race. The event is...

Addiction research centres and the nurturing of creativity: The Alcohol & Drug Abuse Research Unit at the South African Medical Research Council - strengthening substance abuse research and policy in South Africa.

Science.gov (United States)

Parry, Charles; Morojele, Neo; Myers, Bronwyn; Plüddemann, Andreas

2013-01-01

The Alcohol and Drug Abuse Research Unit (ADARU) was established at the South African Medical Research Council (MRC) at the beginning of 2001, although its origins lie in the activities of the Centre for Epidemiological Research in Southern Africa and other MRC entities. Initial challenges included attracting external funding, recruiting new staff, developing the skills of junior staff, publishing in international journals and building national and international collaborative networks. ADARU currently comprises a core staff of 33 members who work on 22 projects spanning substance use epidemiology and associated consequences, intervention studies with at-risk populations and services research. A large component of this portfolio focuses on the link between alcohol and other drug use and human immunodeficiency virus (HIV) risk behaviour, with funding from the US Centers for Disease Control and Prevention. Junior staff members are encouraged to develop independent research interests and pursue PhD studies. Research outputs, such as the 20 papers that were published in 2010 and the 35 conference presentations from that year, form an important part of the unit's research translation activities. We engage actively with policy processes at the local, provincial, national and international levels, and have given particular attention to alcohol policy in recent years. The paper includes an analysis of major challenges currently facing the unit and how we are attempting to address them. It ends with some thoughts on what the unit intends doing to enhance the quality of its research, the capacity of its staff and its international standing. © 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.

Anatomical relationship between traditional acupuncture point ST 36 and Omura's ST 36 (True ST 36) with their therapeutic effects: 1) inhibition of cancer cell division by markedly lowering cancer cell telomere while increasing normal cell telomere, 2) improving circulatory disturbances, with reduction of abnormal increase in high triglyceride, L-homocystein, CRP, or cardiac troponin I & T in blood by the stimulation of Omura's ST 36--Part 1.

Science.gov (United States)

Omura, Yoshiaki; Chen, Yemeng; Lu, Dominic P; Shimotsura, Yasuhiro; Ohki, Motomu; Duvvi, Harsha

2007-01-01

Using Bi-Digital O-Ring Test Resonance Phenomena between 2 identical substances, Omura, Y. succeeded in making the image of the outline of internal organs without use of standard imaging devices since 1982. When he imaged the outline of the stomach on the abdominal wall, a number of the lines came out from upper and lower parts of stomach wall. When the lines were followed, they were very close to the well-known stomach meridians. Subsequently, he found a method of localizing meridians and their corresponding acupuncture points as well as shapes and diameters accurately. At the anatomical location of ST 36 described in traditional textbooks, Omura, Y. found there is no acupuncture point. However, in the close vicinity, there is an acupuncture point which he named as true ST 36 in the mid 1980s, but it is generally known as Omura's ST 36. When the effects of the acupuncture on these 2 locations were compared, Omura's ST 36 (true ST 36) produced very significant well-known acupuncture beneficial effects including improved circulation and blood chemistry, while in the traditional ST 36, the effects were small. In this article, the anatomical relationship between these two acupuncture points, with a short distance of 0.6 approximately 1.5 cm between the centers of these locations, was described. In early 2000, Omura, Y. found Press Needle Stimulation of Omura's ST 36, using "Press-Release" procedure repeated 200 times, 4 times a day to cancer patients reduced high cancer cell telomere of 600-1500ng and high Oncogen C-fos Ab2 and Integrin alpha5beta1 of 100-700ng BDORT units to close to lyg (= 10(-24) g) BDORT units. In addition there was a significant reduction of Asbestos and Hg from cancer cells, while markedly reduced normal cell telomere of lyg was increased to optimally high amounts of 500-530ng BDORTunits. Thus, cancer cells can no longer divide and cancer activity is inhibited. The authors have successfully applied this method for a variety of cancers as well as

Knowledge and Understanding of 21st Century Skills through Educator Externships: Programs in Southern New England

Science.gov (United States)

Gibson-Cayouette, Lizann R.

2010-01-01

An acute shortage of a competent, highly-skilled workforce faces the United States workplace. Studies and reports from 1983 to present, repeatedly state that the education system in the United States must change to prepare the emergent workforce for success in the 21st century global challenges of both post-secondary education and the workplace.…

21st Century Heat Stress Projections and their Effects on US Livestock

Science.gov (United States)

McCabe, E.; Buzan, J. R.; Krishnan, S.; Huber, M.

2016-12-01

In this study we aim to determine future yield changes in the United States for livestock caused by heat stress, under the high greenhouse gas emissions scenario, representative concentration pathway 8.5 (RCP8.5). We use CMIP5 output and the Community Earth System Model Large Ensemble (CESM LENS), produced by the National Center for Atmospheric Research (NCAR). We apply the HumanIndexMod, a diagnostic heat stress package, to calculate Temperature Humidity Index for Comfort (THIC) and wet bulb temperature (Buzan et al., 2015). THIC is used to assess an animal's behavioral changes as it is subjected to discomfort. Using output from our simulations with the HumanIndexMod, we utilized the agricultural livestock model of St. Pierre et al. (2003). THIC and wet bulb temperatures are all projected by climate models to increase by the end of the century. We found that increases in THIC and heat stress are caused by both temperature and humidity increases. We show the differences for dry matter intake loss and milk loss for the Dairy Cow Model as well as other yield related variables. These variables are estimated to decrease overall production for dairy cattle, finishing hogs, poultry and various livestock. By the end of the 21st century (2071-2100), dairy cow milk production decreases by 14%, and food intake decreases by 11% compared to the beginning of the century (2005-2034). 35% less weight is gained and 19% less food is consumed by hogs the end of the century compared to the beginning of the century. We estimate and discuss resulting yield losses for the livestock industries and the implications of these losses in the United States. These results indicate that the effect of heat stress on livestock production will be highest for dairy cows, finishing hogs, and poultry.References:Buzan, J.R., K. Oleson, and M. Huber. 2015. Implementation and comparison of a suite of heat stress metrics within the Community Land Model version 4.5. Geoscien. Model Devel. 8(2): 151-170. St

Research on novel coal conversion technology for energy and environment in 21st century

Energy Technology Data Exchange (ETDEWEB)

T. Takarada [Gunma University (Japan)

2003-07-01

In the 21st century, more efficient coal conversion technology will be needed. In this paper, novel gasification, pyrolysis and desulfurization processes using active catalysts are introduced. In particular, the application of ion-exchanged metals in brown coal to coal conversion technology is featured in this study. Other topics discussed include: Catalysis of mineral matter in coal; Catalytic effectiveness of Ni and K{sub 2}CO{sub 3} for various coals; Direct production of methane from steam gasification; Preparation of active catalysts from NaCl and KCl using brown coal; Gasification of high rank coal by mixing K-exchanged brown coal; Recovery of sulfur via catalytic SO{sub 2} gasification of coal char; Research on novel coal conversion technology BTX production by hydropyrolysis of coal in PPFB using catalyst; High BTU gas production by low-temperature catalytic hydropyrolysis of coal; and Ca-exchanged brown coal as SO{sub 2} and H{sub 2}S sorbents. 12 refs., 17 figs.

Integration of the "Americas" in the 21st Century

National Research Council Canada - National Science Library

Guimaraes, Milton

2001-01-01

Through a program of comprehensive research and detailed analysis, the paper presents current and proposed steps for the Integration of the Americas in the 21st Century within the time frame agreed...

33 CFR 100.915 - St. Clair River Classic Offshore Race, St. Clair, MI.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false St. Clair River Classic Offshore Race, St. Clair, MI. 100.915 Section 100.915 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.915 St. Clair River...

Internship report on palliative care at St Catherine's hospice

OpenAIRE

Monteiro, Andreia Marlene da Silva

2016-01-01

This report, performed in the context of the completion of the masters in Palliative Care, presents the activities and learning experiences that I have acquired during the months of training in the different settings of palliative care. This internship was performed at St Catherine’s Hospice (Inpatient unit, Day hospice and Community team) and with the National Health Service of East Surrey Hospital Specialist Palliative Care Team. Alongside the institutional involvement, internship activitie...

Church of St. Peter and Paul in the village under Kopaonik

Directory of Open Access Journals (Sweden)

Raičević Slobodan

2009-01-01

. Peter and St. Paul. In the association line there are five icons scenes: Birth, Baptism, Resurrection of Lazarus, Resurrection of Christ and the Last Supper and so the icons of St. Trinity, Archangel Michael, the prophet Elijah in the wilderness and Ascension of St. Elijah. The crown of the iconostasis is a cross with the notion of Christ's crucifixion. In the church is located a few more icons: Celivajuća icons from the 1899, mutually painted flag with scenes of Christ's Birth and patron of St. Apostles Peter and Paul, naively painted the clerical throne, and a copy of the harp. Who were zografs of these paintings units, we still can not exactly say, but some details lead to the conclusion that these paintings, originally, are works of the painters from the south, from western Macedonia, those, who in the late 19th and early 20th century acted on the territory of Kosovo and Metohija, in Peć and in the Old Vlaho. Maybe the works might be of the brothers Dičić from Debra, masters who based theirs paintings of models and solutions known master Hristifor Žefarović or on the part of his followers in church painting with us.

Emergence in Taiwan of novel imipenem-resistant Acinetobacter baumannii ST455 causing bloodstream infection in critical patients.

Science.gov (United States)

Lee, Hao-Yuan; Huang, Chih-Wei; Chen, Chyi-Liang; Wang, Yi-Hsin; Chang, Chee-Jen; Chiu, Cheng-Hsun

2015-12-01

Acinetobacter baumannii is one of the most important nosocomial pathogens worldwide. This study aimed to use multilocus sequence typing (MLST) for the epidemiological surveillance of A. baumannii isolates in Taiwan and analyze the clinical presentations and patients' outcome. MLST according to both Bartual's PubMLST and Pasteur's MLST schemes was applied to characterize bloodstream imipenem-resistant A. baumannii (IRAB) infection in intensive care units in a medical center. A total of 39 clinical IRAB bloodstream isolates in 2010 were enrolled. We also collected 13 imipenem-susceptible A. baumannii (ISAB) bloodstream isolates and 30 clinical sputum isolates (24 IRAB and 6 ISAB) for comparison. Clinical presentations and outcome of the patients were analyzed. We found that infection by ST455(B)/ST2(P) and inappropriate initial therapy were statistically significant risk factors for mortality. More than one-third of the IRAB isolates belonged to ST455(B)/ST2(P). Most ST455(B)/ST2(P) (80%) carried ISAba1-blaOXA-23, including 10 (66.7%) with Tn2006 (ISAba1-blaOXA-23-ISAba1) in an AbaR4-type resistance island. ST455(B)/ST2(P) appears to evolve from ST208(B)/ST2(P) of clonal complex (CC) 92(B)/CC2(P). In this hospital-based study, A. baumannii ST455 accounted for 38.5% of IRAB bacteremia, with a high mortality of 86.7%. Approximately 85% of ST455(B)/ST2(P)bacteremia had a primary source of ventilation-associated pneumonia. We report the emergence in Taiwan of IRAB ST455(B)/ST2(P), which is the current predominant clone of IRAB in our hospital and has been causing bacteremia with high mortality in critical patients. Copyright © 2015. Published by Elsevier B.V.

Computational fluid dynamics research at the United Technologies Research Center requiring supercomputers

Science.gov (United States)

Landgrebe, Anton J.

1987-01-01

An overview of research activities at the United Technologies Research Center (UTRC) in the area of Computational Fluid Dynamics (CFD) is presented. The requirement and use of various levels of computers, including supercomputers, for the CFD activities is described. Examples of CFD directed toward applications to helicopters, turbomachinery, heat exchangers, and the National Aerospace Plane are included. Helicopter rotor codes for the prediction of rotor and fuselage flow fields and airloads were developed with emphasis on rotor wake modeling. Airflow and airload predictions and comparisons with experimental data are presented. Examples are presented of recent parabolized Navier-Stokes and full Navier-Stokes solutions for hypersonic shock-wave/boundary layer interaction, and hydrogen/air supersonic combustion. In addition, other examples of CFD efforts in turbomachinery Navier-Stokes methodology and separated flow modeling are presented. A brief discussion of the 3-tier scientific computing environment is also presented, in which the researcher has access to workstations, mid-size computers, and supercomputers.

Public Spending on Health Service and Policy Research in Canada, the United Kingdom, and the United States: A Modest Proposal

Directory of Open Access Journals (Sweden)

Vidhi Thakkar

2017-11-01

Full Text Available Health services and policy research (HSPR represent a multidisciplinary field which integrates knowledge from health economics, health policy, health technology assessment, epidemiology, political science among other fields, to evaluate decisions in health service delivery. Health service decisions are informed by evidence at the clinical, organizational, and policy level, levels with distinct, managerial drivers. HSPR has an evolving discourse spanning knowledge translation, linkage and exchange between research and decision-maker partners and more recently, implementation science and learning health systems. Local context is important for HSPR and is important in advancing health reform practice. The amounts and configuration of national investment in this field remain important considerations which reflect priority investment areas. The priorities set within this field or research may have greater or lesser effects and promise with respect to modernizing health services in pursuit of better value and better population outcomes. Within Canada an asset map for HSPR was published by the national HSPR research institute. Having estimated publiclyfunded research spending in Canada, we sought identify best available comparable estimates from the United States and the United Kingdom. Investments from industry and charitable organizations were not included in these numbers. This commentary explores spending by the United States, Canada, and the United Kingdom on HSPR as a fraction of total public spending on health and the importance of these respective investments in advancing health service performance. Proposals are offered on the merits of common nomenclature and accounting for areas of investigation in pursuit of some comparable way of assessing priority HSPR investments and suggestions for earmarking such investments to total investment in health services spending.

St2-80: a new FISH marker for St genome and genome analysis in Triticeae.

Science.gov (United States)

Wang, Long; Shi, Qinghua; Su, Handong; Wang, Yi; Sha, Lina; Fan, Xing; Kang, Houyang; Zhang, Haiqin; Zhou, Yonghong

2017-07-01

The St genome is one of the most fundamental genomes in Triticeae. Repetitive sequences are widely used to distinguish different genomes or species. The primary objectives of this study were to (i) screen a new sequence that could easily distinguish the chromosome of the St genome from those of other genomes by fluorescence in situ hybridization (FISH) and (ii) investigate the genome constitution of some species that remain uncertain and controversial. We used degenerated oligonucleotide primer PCR (Dop-PCR), Dot-blot, and FISH to screen for a new marker of the St genome and to test the efficiency of this marker in the detection of the St chromosome at different ploidy levels. Signals produced by a new FISH marker (denoted St 2 -80) were present on the entire arm of chromosomes of the St genome, except in the centromeric region. On the contrary, St 2 -80 signals were present in the terminal region of chromosomes of the E, H, P, and Y genomes. No signal was detected in the A and B genomes, and only weak signals were detected in the terminal region of chromosomes of the D genome. St 2 -80 signals were obvious and stable in chromosomes of different genomes, whether diploid or polyploid. Therefore, St 2 -80 is a potential and useful FISH marker that can be used to distinguish the St genome from those of other genomes in Triticeae.

Directions of ICF research in the United States

International Nuclear Information System (INIS)

Hogan, W.J.; Campbell, E.M.

1997-01-01

Inertial confinement fusion (ICF) research in the United States is in a dramatic upswing. Technical progress continues at a rapid pace and with the start of the construction of the National Ignition Facility (NIF) this year the total U.S. budget for ICF for fiscal year 1997 stands at $380 million. The NIF is being built as an essential component of the U.S. Stockpile Stewardship and Management Program which has been formulated to assure the continued safety, reliability, and performance of the downsized nuclear weapons stockpile in the absence of nuclear tests. This paper will discuss some of the directions that the ICF research is now taking. (AIP) copyright 1997 American Institute of Physics

Performance Evaluation and Opportunity Assessment for St. Bernard Project

Energy Technology Data Exchange (ETDEWEB)

Dickson, B.

2011-06-01

This report describes efforts by IBACOS, a Department of Energy Building America research team, in the St. Bernard Project, a nonprofit, community-based organization whose mission is to assist Hurricane Katrina survivors return to their homes in the New Orleans area. The report focuses on energy modeling results of two plans that the St. Bernard Project put forth as 'typical' building types and on quality issues that were observed during the field walk and Best Practice recommendations that could improve the energy efficiency and durability of the renovated homes.

Performance Evaluation and Opportunity Assessment for St. Bernard Project

Energy Technology Data Exchange (ETDEWEB)

Dickson, Bruce [IBACOS, Inc., Pittsburgh, PA (United States)

2011-06-01

This report describes efforts by IBACOS, a Building America research team, in the St. Bernard Project, a nonprofit, community-based organization whose mission is to assist Hurricane Katrina survivors to return to their homes in the New Orleans area. The report focuses on energy modeling results of two plans that the St. Bernard Project put forth as 'typical' building types and on quality issues that were observed during the field walk and best practice recommendations that could improve the energy efficiency and durability of the renovated homes.

Multiple protein biomarker assessment for recombinant bovine somatotropin (rbST abuse in cattle.

Directory of Open Access Journals (Sweden)

Susann K J Ludwig

programmes: in the European Union for detection of rbST abuse and in the control of rbST-free dairy farms in the United States of America and other countries.

Anguilla rostrata glass eel migration and recruitment in the estuary and Gulf of St Lawrence.

Science.gov (United States)

Dutil, J-D; Dumont, P; Cairns, D K; Galbraith, P S; Verreault, G; Castonguay, M; Proulx, S

2009-06-01

This study describes catches of Anguilla rostrata glass eels and associated oceanographic conditions in the St Lawrence Estuary and Gulf. Ichthyoplankton survey data suggest that they enter the Gulf primarily in May, migrate at the surface at night, and disperse broadly once they have passed Cabot Strait. They arrive in estuaries beginning at about mid-June and through the month of July. Migration extends west up to Québec City, in the freshwater zone of the St Lawrence Estuary, 1000 km west of Cabot Strait. Anguilla rostrata glass eels travel between Cabot Strait and receiving estuaries at a straight-line ground speed of c. 10-15 km day(-1). Catches of fish per unit effort in estuaries in the St Lawrence system are much lower than those reported for the Atlantic coast of Canada. Low abundance of A. rostrata glass eels in the St Lawrence system may be due to cold surface temperatures during the migration period which decrease swimming capacity, long distances from the spawning ground to Cabot Strait and from Cabot Strait to the destination waters (especially the St Lawrence River), complex circulation patterns, and hypoxic conditions in bottom waters of the Laurentian Channel and the St Lawrence Estuary.

Final environmental statement related to the operation of St. Lucie Plant, Unit No. 2. Docket No. 50-389, Florida Power and Light Company, Orlando Utilities Commission of the City of Orlando, Florida

International Nuclear Information System (INIS)

1982-04-01

This final environmental statement was prepared by the US Nuclear Regulatory Commission (NRC), Office of Nuclear Reactor Regulation (the staff) in accordance with the Commission's Regulations, set forth in 10 CFR Part 51, which implement the requirements of the National Environmental Policy Act of 1969 (NEPA). Sections related to the aquatic environment were prepared in cooperation with the US Environmental Protection Agency, Region IV. This statement reviews the impact of operation of the St. Lucie Plant, Unit 2. Assessments that are found in this statement supplement those described in the Final Environmental Statement (FES-CP) that was issued in May 1974 in support of issuance of a construction permit for the unit

From research to policy and practice: the School of the 21st Century.

Science.gov (United States)

Zigler, Edward; Finn-Stevenson, Matia

2007-04-01

Current education reform policies focus on raising academic achievement and ensuring that all students have access to high-quality education. Because the achievement gap is apparent even before children enter school, the authors believe that education reform must encompass the early childhood years. The current dialogue about universal preschool presents an opportunity to address the need for a national system for early care and education. The authors believe this system should provide quality child care and preschool experiences for all children and embrace a whole-child approach that nurtures not only cognitive development but physical and mental health and social-emotional behaviors that are also important to successful schooling. The School of the 21st Century provides an example of an effective early care and education system using the public schools. The authors' work with the School of the 21st Century shows that schools can provide high-quality, developmentally appropriate care and that these programs benefit later school performance. 2007 APA, all rights reserved

76 FR 44531 - Safety Zone; Fourth Annual Chillounge Night St. Petersburg Fireworks Display, Tampa Bay, St...

Science.gov (United States)

2011-07-26

...-AA00 Safety Zone; Fourth Annual Chillounge Night St. Petersburg Fireworks Display, Tampa Bay, St... proposes to establish a temporary safety zone on the waters of Tampa Bay in St. Petersburg, Florida during the Fourth Annual Chillounge Night St. Petersburg Fireworks Display on Saturday, November 19, 2011...

76 FR 68098 - Safety Zone; Fourth Annual Chillounge Night St. Petersburg Fireworks Display, Tampa Bay, St...

Science.gov (United States)

2011-11-03

...-AA00 Safety Zone; Fourth Annual Chillounge Night St. Petersburg Fireworks Display, Tampa Bay, St... Guard is establishing a temporary safety zone on the waters of Tampa Bay in St. Petersburg, Florida during the Fourth Annual Chillounge Night St. Petersburg Fireworks Display on Saturday, November 19, 2011...

Music Education in the 21st Century in the United Kingdom: Achievements, Analysis and Aspirations

Science.gov (United States)

Hallam, Susan, Ed.; Creech, Andrea. Ed.

2010-01-01

The landscape of music education in the UK is constantly shifting and developing. This book provides a timely and unique overview of this restless sector by considering the achievements of music education, analysing its current performance and setting out aspirations for the future. "Music Education in the 21st Century in the United…

Making Research Matter Comment on "Public Spending on Health Service and Policy Research in Canada, the United Kingdom, and the United States: A Modest Proposal".

Science.gov (United States)

Hunter, David J; Frank, John

2017-08-13

We offer a UK-based commentary on the recent "Perspective" published in IJHPM by Thakkar and Sullivan. We are sympathetic to the authors' call for increased funding for health service and policy research (HSPR). However, we point out that increasing that investment - in any of the three countries they compare: Canada, the United States and the United Kingdom- will ipso facto not necessarily lead to any better use of research by health system decision-makers in these settings. We cite previous authors' descriptions of the many factors that tend to make the worlds of researchers and decision-makers into "two solitudes." And we call for changes in the structure and funding of HSPR, particularly the incentives now in place for purely academic publishing, to tackle a widespread reality: most published research in HSPR, as in other applied fields of science, is never read or used by the vast majority of decision-makers, working out in the "real world. © 2018 The Author(s); Published by Kerman University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Evaluating the impact of a partnership for creating change in substance misuse practice in St. Petersburg, Russia.

Science.gov (United States)

Green, Anita J; Holloway, David G

2005-11-01

This paper reports on an evaluation of an innovative education and training programme for nurses and narcologists in St. Petersburg, Russia. The aims of the evaluation were: first, to evaluate the effect of the education and training programme on the clinical practice of doctors and nurses who have had direct contact with the programme and, second, to evaluate the influence of the education and training programme on city-wide drug and alcohol policy and practice. Brief contextual information regarding the programme is provided prior to an account of the qualitative methodology. Particular attention was paid to the work of Patton [Utilisation-focused evaluation, second ed., Sage, London, 1986; Qualitative research and evaluation methods, third ed., Sage, London, 2002] for the theoretical framework and to Hantais and Mangen [Cross-national research methods in the social sciences, Pinter, London, 1996] regarding the methodological issues that surround international and cross-cultural research projects. Data collection was carried out in St. Petersburg and in the United Kingdom, which involved key participants in the programme. The data analysis followed Miles and Huberman [Qualitative data analysis. An expanded sourcebook, second ed. Sage, Thousand Oaks, 1994] which yielded six major themes: rehabilitation, the role and continuing professional development of the trained nurse; the status of the nurse training-college and the staff, small scale projects and their significance; sharing experiences/networking/face-to-face meetings; and, lack of resistance. The findings are discussed and recommendations for further involvement are identified.

St. Jude Cancer Education for Children Program: The Impact of a Teacher-Led Intervention on Student Knowledge Gains.

Science.gov (United States)

Ayers, Katherine; Li, Zhenghong; Quintana, Yuri; Van Kirk Villalobos, Aubrey; Klosky, James L

2017-12-01

In 2006, St. Jude Children's Research Hospital (Memphis, Tennessee) began developing a school-based outreach program known as the St. Jude Cancer Education for Children Program (SJCECP). The aim of this program is to teach Memphis-area children about cells, cancer, and healthy habits that can prevent the development of cancer in adulthood. Initial plans for delivery of the program was for St. Jude staff to present the program at local schools. This plan for disseminating instruction was not feasible due to the limited availability of St. Jude staff. As a next step, during the 2012-2014 academic years, we conducted a study entitled SJCECP2, utilizing the SJCECP curriculum, with the objective of evaluating the impact of the educational intervention on knowledge acquisition and retention among fourth-grade students participating in a modified, teacher-led version of the program. Eighteen teachers and 426 students from 10 local schools in the greater Memphis area participated in the program evaluation. This study used a single-group, pre-test/post-test design to determine the impact of the SJCECP intervention on changes in knowledge scores among fourth-grade students. Testing was on cells, cancer, and healthy living. The mean scores increased from 6.45 to 8.12, 5.99 to 7.65, and 5.92 to 7.96 on cell, cancer, and health behaviors units, respectively (all p values <.001). Preliminary evidence suggests that the SJCECP2 intervention is a useful tool for teachers to improve student knowledge of knowledge of cells, cancer, and healthy living concepts at the fourth-grade level.

International stem cell collaboration: how disparate policies between the United States and the United Kingdom impact research.

Science.gov (United States)

Luo, Jingyuan; Flynn, Jesse M; Solnick, Rachel E; Ecklund, Elaine Howard; Matthews, Kirstin R W

2011-03-08

As the scientific community globalizes, it is increasingly important to understand the effects of international collaboration on the quality and quantity of research produced. While it is generally assumed that international collaboration enhances the quality of research, this phenomenon is not well examined. Stem cell research is unique in that it is both politically charged and a research area that often generates international collaborations, making it an ideal case through which to examine international collaborations. Furthermore, with promising medical applications, the research area is dynamic and responsive to a globalizing science environment. Thus, studying international collaborations in stem cell research elucidates the role of existing international networks in promoting quality research, as well as the effects that disparate national policies might have on research. This study examined the impact of collaboration on publication significance in the United States and the United Kingdom, world leaders in stem cell research with disparate policies. We reviewed publications by US and UK authors from 2008, along with their citation rates and the political factors that may have contributed to the number of international collaborations. The data demonstrated that international collaborations significantly increased an article's impact for UK and US investigators. While this applied to UK authors whether they were corresponding or secondary, this effect was most significant for US authors who were corresponding authors. While the UK exhibited a higher proportion of international publications than the US, this difference was consistent with overall trends in international scientific collaboration. The findings suggested that national stem cell policy differences and regulatory mechanisms driving international stem cell research in the US and UK did not affect the frequency of international collaborations, or even the countries with which the US and UK most

Research ethics I: Responsible conduct of research (RCR)--historical and contemporary issues pertaining to human and animal experimentation.

Science.gov (United States)

Horner, Jennifer; Minifie, Fred D

2011-02-01

In this series of articles--Research Ethics I, Research Ethics II, and Research Ethics III--the authors provide a comprehensive review of the 9 core domains for the responsible conduct of research (RCR) as articulated by the Office of Research Integrity. In Research Ethics I, they present a historical overview of the evolution of RCR in the United States then examine the evolution of human and animal experimentation from the birth of scientific medicine through World War II to the present day. They relied on authoritative documents, both historical and contemporary, insightful commentary, and empirical research in order to identify current issues and controversies of potential interest to both faculty and students. The authors have written this article from a historical perspective because they think all readers interested in RCR should appreciate how the history of science and all the good--and harm--it has produced can inform how researchers practice responsible research in the 21st century and beyond.

U.S. Geological Survey Cooperative Fish and Wildlife Research Units Program—2016–2017 Research Abstracts

Science.gov (United States)

Dennerline, Donald E.; Childs, Dawn E.

2017-04-20

The U.S. Geological Survey (USGS) has several strategic goals that focus its efforts on serving the American people. The USGS Ecosystems Mission Area has responsibility for the following objectives under the strategic goal of “Science to Manage and Sustain Resources for Thriving Economies and Healthy Ecosystems”:Understand, model, and predict change in natural systemsConserve and protect wildlife and fish species and their habitatsReduce or eliminate the threat of invasive species and wildlife diseaseThis report provides abstracts of the majority of ongoing research investigations of the USGS Cooperative Fish and Wildlife Research Units program and is intended to complement the 2016 Cooperative Research Units Program Year in Review Circular 1424 (https://doi.org/10.3133/cir1424). The report is organized by the following major science themes that contribute to the objectives of the USGS:Advanced TechnologiesClimate ScienceDecision ScienceEcological FlowsEcosystem ServicesEndangered Species Conservation, Recovery, and Proactive StrategiesEnergyHuman DimensionsInvasive SpeciesLandscape EcologySpecies of Greatest Conservation NeedSpecies Population, Habitat, and Harvest ManagementWildlife Health and Disease

Policy perspective on the global use of Smokeless Tobacco (ST: a literature review

Directory of Open Access Journals (Sweden)

Kamran Siddiqi

2018-03-01

gaps in the implementation of key demand-reduction measures with regard to ST. Methods A series of focused literature reviews was conducted and findings were synthesized by relevant Articles (6 - 14 of the World Health Organization Framework Convention on Tobacco Control (WHO FCTC. Results We found sufficient evidence to support implementation of key demand-reduction measures for ST. For example, raising taxes can reduce ST consumption, with price elasticity on a par with, or sometimes higher than, cigarettes. Similarly, graphic pictorial warnings on ST packaging are far more effective than text-only warning labels. But despite supportive evidence, countries have either not implemented measures or have kept the bar much lower than that for cigarettes. For example, very few countries regulate the contents of ST products. Some have raised ST taxes but not to the extent of cigarette taxes, risking product substitution. Similarly, health-warning requirements for ST are less strict than those for cigarettes. Even where strong policies exist, compliance has been poor. For example, despite bans on ST advertising, most suppliers continue to promote products, especially at points of sale and via print and digital media. Consequently, ST demand-reduction measures have had limited impact. Conclusions The full implementation of FCTC Articles 6-14 is likely to reduce the global demand for ST, but their current state of implementation lags behind that for cigarettes. The existing policy gaps can be addressed through better knowledge of ST products, setting unambiguous standards, innovative systems for tax administration, building capacity in testing ST products and undertaking targeted research.

Recent Progress on Spherical Torus Research

Energy Technology Data Exchange (ETDEWEB)

Ono, Masayuki [PPPL; Kaita, Robert [PPPL

2014-01-01

The spherical torus or spherical tokamak (ST) is a member of the tokamak family with its aspect ratio (A = R0/a) reduced to A ~ 1.5, well below the normal tokamak operating range of A ≥ 2.5. As the aspect ratio is reduced, the ideal tokamak beta β (radio of plasma to magnetic pressure) stability limit increases rapidly, approximately as β ~ 1/A. The plasma current it can sustain for a given edge safety factor q-95 also increases rapidly. Because of the above, as well as the natural elongation κ, which makes its plasma shape appear spherical, the ST configuration can yield exceptionally high tokamak performance in a compact geometry. Due to its compactness and high performance, the ST configuration has various near term applications, including a compact fusion neutron source with low tritium consumption, in addition to its longer term goal of attractive fusion energy power source. Since the start of the two megaampere class ST facilities in 2000, National Spherical Torus Experiment (NSTX) in the US and Mega Ampere Spherical Tokamak (MAST) in UK, active ST research has been conducted worldwide. More than sixteen ST research facilities operating during this period have achieved remarkable advances in all of fusion science areas, involving fundamental fusion energy science as well as innovation. These results suggest exciting future prospects for ST research both near term and longer term. The present paper reviews the scientific progress made by the worldwide ST research community during this new mega-ampere-ST era.

Framatome technologies awarded nickel plating contract at St. Lucie

International Nuclear Information System (INIS)

Anon.

1997-01-01

Framatome Technologies is to perform nickel plating on 120 pressurizer heater sleeves at Florida Power and Light's St. Lucie unit 1 during the fall 1997 outage; replacement heaters, fabricated by Framatome, that use stainless steel for the heather sheath, will be installed. The nickel layer is deposited on the inside surface of the heater sleeves, which protects the Inconel 600 material and significantly reduces the intergranular stress-corrosion cracking, as proved in other US and European plants

Perceptions of Medicinal Plant Use Amongst the Hispanic Population in the St. Louis Metropolitan Area

Directory of Open Access Journals (Sweden)

Kim M. Grafford

2016-10-01

Full Text Available Introduction: Medicinal plant use in the United States has increased as reported by the National Center of Complementary and Integrative Health and U.S. Census Bureau.However, little is known about how many minority groups in the United States use medicinal plants.There is a rise in the Hispanic population; a community with a steep tradition of medicinal plant use, in the U.S., so understanding the perceptions of medicinal plant use is useful to healthcare providers. Methods: A survey was designed to gauge a better understanding of the perceptions of medicinal plant use amongst Latino patients with varying education levels who reside in the St. Louis Metropolitan Area. Survey questions highlighted the perceptions of medicinal plants use, patient communication regarding medicinal plant use with healthcare providers (pharmacists and doctors, and the impact the education level has on medicinal plant use. Results: Surveys were distributed to six different investigational sites around the St. Louis Metropolitan Area from August 2015 to December 2015. Survey respondents identified 45 different plants/herbs that they currently use or had used at some point in their life. Those with higher levels of education had varying opinions on medicinal plant use with their current practices. Conclusion: The participants’ high interest in the use of medicinal plants exemplifies the need for enhanced communication between patients and healthcare professionals about medicinal plant use. However, it was hard to determine whether the participants’ level of education had any direct relationship to this use. Conflict of Interest None   Type: Original Research

Economics of conservation systems research in the Southeastern United States

Science.gov (United States)

The use of conservation systems in crop production is not a new concept in the southeastern United States. In 1978, researchers from across the Southeast met in Griffin, Georgia for the first annual Southern Conservation Agricultural Systems Conference. Four of the ten presentations specifically men...

ST peak during percutaneous coronary intervention serves as an early prognostic predictor in patients with ST-segment elevation myocardial

DEFF Research Database (Denmark)

Lønborg, Jacob; Kelbæk, Henning; Engstrøm, Thomas

2014-01-01

AIMS: To evaluate the clinical importance of the ST peak phenomenon during primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI). METHODS AND RESULTS: Continuous ST monitoring was performed in 942 STEMI patients from arrival until 90...... minutes after revascularisation. ST peak was defined as ≥1 mm increase in the ST-segment during PCI compared with the ST elevation before intervention. ST peak was observed in 26.9% of patients. During median follow-up of 4.1 years, 20.7% of patients experienced a major adverse cardiac event (MACE). ST...... and ST peak including ST resolution and epicardial flow, ST peak remained significantly associated with MACE: adjusted hazard ratio (HR) 1.40 (95% confidence interval [CI] 1.01-1.95) and 1.41 (95% CI: 1.02-1.96). CONCLUSIONS: In the largest study hitherto evaluating the ST peak phenomenon during primary...

Assessing the effect of an online HIV/AIDS course on 1st-year ...

African Journals Online (AJOL)

Background. More international HIV/AIDS intervention initiatives targeting young adults are needed to help reach targets set by the Joint United Nations Programme on HIV and AIDS (UNAIDS). Objectives. To determine the effect of an online HIV/AIDS course on 1st-year pharmacy students' knowledge of HIV prevention and ...

Företaget Manchester United : En kontraktsekonomisk studie

OpenAIRE

Ellermann, Daniel; Lönnefelt, Hans

2004-01-01

Denna kontraktsekonomiska studie behandlar fotbollsklubben och företaget Manchester United, en av världens största och framgångsrika klubbar alla kategorier. Syftet med uppsatsen är att dels kartlägga Manchester Uniteds kontraktsnät, dels att begripliggöra de kontraktsrelationer som särskiljer Manchester United från vanliga nuvärdesmaximerande företag utifrån kontraktsekonomisk teori. Den ekonomiska teori som ihuvudsak används i uppsatsen är kontraktsekonomisk teori som innefattar teorier om...

Forest ecohydrological research in the 21st century: what are the critical needs?

Science.gov (United States)

James Vose; Ge Sun; Chelcy Ford; Michael Bredemeier; Kyoichi Ostsuki; Adam Wei; Zhiqiang Zhang; Lu. Zang

2011-01-01

Modern ecohydrologic science will be critical for providing the best information to policy makers and society to address water resource challenges in the 21st century. Implicitly, ecohydrology involves understanding both the functional interactions among vegetation, soils, and hydrologic processes at multiple scales and the linkages among upland, riparian, and aquatic...

21st centuries skill implication on educational system

Science.gov (United States)

Wrahatnolo, T.; Munoto

2018-01-01

The purpose of this article is to identify skill needed in 21st centuries and its implication on Indonesia’s educational system. This research found that the 21st centuries skill application has more measurable benefits in some sections of life, such as critical thinking and problem solving, initiative, creativity, and entrepreneurship, communication, teamwork, metacognition (change of mindset), digital literature. This study applied qualitative data analysis. The data were taken from different sources and literature. The analysis showed that The 21st centuries education concept’s implementation can be applied in the curriculum of the required subject that is addressed to achieve learning and innovation skills competence and also technology and information media skills competence. While supporting subject group directed to achieve life and career skills competence. All subjects are the derivation from core subject 3R, which are reading, writing, and arithmetic. Based on the description above, it can be concluded that 21st centuries skill needs; (1) a life planning; (2) flexibility and adaptability; (3) initiative and self-management (4) entrepreneurship; (5) social and cultural interaction; (6) productivity and accountability; (7) leadership; (8) critical thinking, (9) problem solving; (10) communication; (11) collaboration and teamwork; (12) lifelong learning; and (13) digital literation.

Intensi Berwirausaha Pada Pelajar Kelas Ekstrakurikuler Kewirausahaan SMAK St. Louis 1 Di Surabaya [The Entrepreneurship Intentions of Entrepreneurship Students in Extracurricular Classes at SMAK St. Louis 1 in Surabaya

Directory of Open Access Journals (Sweden)

Gregorius Romaryo Tanubun

2016-10-01

Full Text Available The purpose of this research is to understand: (1 the influence of family on entrepreneur intention; (2 the impact of entrepreneurial study on entrepreneur intention; and (3 the difference in entrepreneurial intention among an entrepreneurial class of students at SMAK St. Louis 1 in Surabaya. The population of this research is students of an entrepreneurial class at SMAK St. Louis 1 in  Surabaya. The sampling technique used is census with 40 respondents as samples. This research is a quantitative research with multiple regression method and independent samples t-test with SPSS 23 as analysis tool. The findings of this research indicate that: (1 family variable (K reacts significantly negative towards entrepreneurial intention (IB, (2 entrepreneurial education variable (PK reacts significantly towards entrepreneurial intention (IB, and (3 no difference is found between men and women.

Smokeless tobacco use in the United States military: a systematic review.

Science.gov (United States)

Bergman, Hannah E; Hunt, Yvonne M; Augustson, Erik

2012-05-01

Smokeless tobacco (ST) use represents an important target for intervention in the U.S. military population because it impairs "military readiness" and harms the health of the military. This paper aims to provide a systematic review of ST studies conducted in the U.S. military population in order to assess the content of existing ST research in this population, provide estimates of prevalence and clinically relevant use patterns, and discuss how these findings might be used to guide future ST research among this population. We reviewed articles published through December 2010 using PubMed and PsycINFO databases, Google Scholar, and any relevant articles' reference lists. Inclusion criteria included focus on a U.S. military sample, English language, measured tobacco use, and ST prevalence was reported or could be calculated. To the extent possible, each article was coded for demographics, socioeconomic status, prevalence, amount, frequency, and length of use, and quit intentions/attempts. Thirty-nine articles met criteria for inclusion. Less than half focused primarily on ST use among military personnel. The remaining studies measured ST use in the context of other behaviors. Findings related to clinically relevant behaviors included a need for more cohort and intervention studies, a better understanding of ST use in combination with cigarettes (i.e., concurrent use), and identifying risk factors for ST initiation and use. ST use is prevalent among military personnel, as is concurrent use of cigarettes and ST. We provide a number of recommendations to guide future research in this important, yet understudied, area.

Research priorities for specialized nursing practice in the United Arab Emirates.

Science.gov (United States)

Al-Yateem, N; Al-Tamimi, M; Brenner, M; Altawil, H; Ahmad, A; Brownie, S

2017-08-25

Globally, nurses are undertaking expanded and more specialized roles in healthcare planning and service delivery in response to changing patterns and levels of health service demand. This means the nursing profession is increasingly considered as leaders in health service policy, research and practice. The United Arab Emirates has strengthened nursing governance and practice by establishing a Nursing and Midwifery Council and increasing the activity of nursing specialization, service leadership and research. This study aimed to identify clinically relevant research priorities to facilitate nursing contributions to evidence-based care and strengthening health services in the country. A two-stage Delphi study design was used. The first round involved 783 participants. The second round involved 1116 participants, as more clinical settings were accessed. In total, 58 research priorities across a variety of nursing specialties (paediatrics, emergency care, intensive care, labour and maternity care, operating theatre and long-term care) were identified as highly important. These identified priorities will guide a more informed programme of research in each nursing specialty, with the aim of strengthening the evidence base to improving outcomes for patients and their families in the United Arab Emirates. The findings provide guidance on key areas for nurses to focus research contributions to enhance evidence-based care and strengthen health systems. The identified priorities may also guide researchers in academic institutions to conduct research informed by current, clinically relevant issues. The findings may help inform funders and policymakers to support allocation of funding to research that has potential to contribute to enhancing nursing care in specialist areas. © 2017 International Council of Nurses.

FFUSION yearbook 1996. Annual report of the Finnish research unit. Association EURATOM-TEKES

Energy Technology Data Exchange (ETDEWEB)

Karttunen, S; Paettikangas, T [eds.; VTT Energy, Espoo (Finland)

1997-05-01

Finnish fusion programme (FFUSION) is one of the eleven national energy research programmes funded by the Technological Development Centre of Finland (TEKES). The FFUSION programme was fully integrated into European Fusion Programme just after Finland joined the European Union. The contract of Association Euratom and Tekes was signed in 1995 and extends to the end of 1999. Finland became a member of JET Joint Undertaking in 1996, other contracts with Euratom include NET agreement and the Staff Mobility Agreement. FFUSION programme with participating research institutes and universities forms the Fusion Research Unit of the Association Euratom-Tekes. This annual report summarises the research activities of the Finnish Research Unit in 1996. The programme consists of two parts: Physics and Technology. The research areas of the physics are: Fusion plasma engineering, Radio-frequency heating and plasma diagnostics, and Plasma-wall interactions - ion-beam studies. The technology is focused into three areas: Fusion reactor materials (first wall components and joining techniques), Remote handling and viewing systems, and Superconductors

The Best Practice Unit: a model for learning, research and development

Directory of Open Access Journals (Sweden)

Jean Pierre Wilken

2013-06-01

Full Text Available The Best Practice Unit: a model for learning, research and development The Best Practice Unit (BPU model constitutes a unique form of practice-based research. A variant of the Community of Practice model developed by Wenger, McDermott and Snyder (2002, the BPU has the specific aim of improving professional practice by combining innovation and research. The model is used as a way of working by a group of professionals, researchers and other relevant individuals, who over a period of one to two years, work together towards a desired improvement. The model is characterized by interaction between individual and collective learning processes, the development of new or improved working methods, and the implementation of these methods in daily practice. Multiple knowledge resources are used, including experiential knowledge, professional knowledge and scientific knowledge. The research serves diverse purposes: articulating tacit knowledge, documenting learning and innovation processes, systematically describing the working methods that have been revealed or developed, and evaluating the efficacy of the new methods. Each BPU is supported by a facilitator, whose main task is to optimize learning processes. An analysis of ten different BPUs in different professional fields shows that this is a successful model. The article describes the methodology and results of this study. De Best Practice Unit: een model voor leren, onderzoek en ontwikkeling Het model van de Best Practice Unit (BPU is een unieke vorm van praktijkgericht onderzoek. De Best Practice Unit is een variant van de Community of Practice zoals ontwikkeld door Wenger, McDermott en Snyder (2002 met als specifiek doel om de professionele praktijk te verbeteren door innovatie en onderzoek te combineren. Het model wordt gebruikt om in een periode van 1-2 jaar met een groep professionals, onderzoekers en andere betrokkenen te werken aan een gewenste verbetering. Kenmerkend is de wisselwerking tussen

31 CFR Appendix C to Subpart A of... - United States Customs Service

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false United States Customs Service C Appendix C to Subpart A of Part 1 Money and Finance: Treasury Office of the Secretary of the Treasury... Houston, TX 77029. Phone: (713) 985-6712; FAX: (713) 985-6705. St. Louis: 4477 Woodson Road St. Louis, MO...

From 21st century skills to 21st century human being

DEFF Research Database (Denmark)

Hjøllund, Niels-Peder Osmundsen; Jørgensen, Tobias Heiberg

2017-01-01

In Denmark, in Scandinavia and in all of Europe there is a lot of talk about the skills of the future. But if we want our students to aim for and gain a different learning outcome, we must set new and different standards for the way we teach – and start to walk the talk. The focus of the presenta...... CLD and we must take the next step, where we stop thinking about skills and competencies and start thinking and acting on the fundamental existential implication of the 21st century. What we need now is not more 21st century skills, but 21st century human beings....

21st Century Science as a Relational Process: From Eureka! to Team Science and a Place for Community Psychology

Science.gov (United States)

Tebes, Jacob Kraemer; Thai, Nghi D.; Matlin, Samantha L.

2014-01-01

In this paper we maintain that 21st century science is, fundamentally, a relational process in which knowledge is produced (or co-produced) through transactions among researchers or among researchers and public stakeholders. We offer an expanded perspective on the practice of 21st century science, the production of scientific knowledge, and what community psychology can contribute to these developments. We argue that: 1) trends in science show that research is increasingly being conducted in teams; 2) scientific teams, such as transdisciplinary teams of researchers or of researchers collaborating with various public stakeholders, are better able to address complex challenges; 3) transdisciplinary scientific teams are part of the larger, 21st century transformation in science; 4) the concept of heterarchy is a heuristic for team science aligned with this transformation; 5) a contemporary philosophy of science known as perspectivism provides an essential foundation to advance 21st century science; and 6) community psychology, through its core principles and practice competencies, offers theoretical and practical expertise for advancing team science and the transformation in science currently underway. We discuss the implications of these points and illustrate them briefly with two examples of transdisciplinary team science from our own work. We conclude that a new narrative is emerging for science in the 21st century that draws on interpersonal transactions in teams, and active engagement by researchers with the public to address critical accountabilities. Because of its core organizing principles and unique blend of expertise on the intersection of research and practice, community psychologists are extraordinarily well-prepared to help advance these developments, and thus have much to offer 21st century science. PMID:24496718

Fine typing of methicillin-resistant Staphylococcus aureus isolates using direct repeat unit and staphylococcal interspersed repeat unit typing methods.

Science.gov (United States)

Ho, Cheng-Mao; Ho, Mao-Wang; Li, Chi-Yuan; Lu, Jang-Jih

2015-08-01

Methicillin-resistant Staphylococcus aureus (MRSA) typing is an important epidemiologic tool for monitoring trends and preventing outbreaks. However, the efficiency of various MRSA typing methods for each SCCmec MRSA isolate is rarely evaluated. A total of 157 MRSA isolates from four different regions in Taiwan were typed with five different molecular methods, including SCCmec typing, multilocus sequence typing (MLST), spa typing, mec-associated direct repeat unit (dru) copy number determination, and staphylococcal interspersed repeat unit (SIRU) profiling. There were four SCCmec types, eight MLST types, 15 spa types, 11 dru types, and 31 SIRU profiles. The most common type determined by each molecular typing method was SCCmec III (115 isolates, 73.2%), ST239 (99 isolates, 63.1%), t037 (107 isolates, 68.2%), 14 dru copies (76 isolates, 48.4%), and SIRU profile 3013722 (102 isolates, 65%), respectively. When using the combination of MLST, spa typing, and dru copy number, ST5-t002-4 (n = 8), ST239-t037-14 (n = 68), ST59-t437-9 (n = 9), and ST59-t437-11 (n = 6) were found to be the most common types of SCCmec types II (n = 9), III (n = 115), IV (n = 21), and VT (n = 11) isolates, respectively. SCCmec type III isolates were further classified into 11 dru types. Of the 21 SCCmec type IV isolates, 14 SIRU profiles were found. Seven SIRU patterns were observed in the 11 SCCmec type VT isolates. Different typing methods showed a similar Hunter-Gaston discrimination index among the 157 MRSA isolates. However, dru and SIRU typing methods had a better discriminatory power for SCCmec type III and SCCmec types IV and VT isolates, respectively, suggesting that dru and SIRU can be used to further type these isolates. Copyright © 2013. Published by Elsevier B.V.

Current researches on safety assessment of radioactive waste disposal in the United States

International Nuclear Information System (INIS)

Tasaka, Hiroshi; Kiyose, Ryohei

1980-01-01

Recently, the problem of safe disposal of radioactive waste generated from nuclear fuel cycle becomes more important in Japan. On the other hand, many researches on shallow land burial of low-level wastes and geologic isolation of high-level wastes have been carried out in the United States of America. In this report, the researches on the safety assessment of radioactive waste disposal in the United States of America were briefly introduced with emphasis on the studies on behavior and migration of radionuclide from disposed waste in geosphere. (author)

76 FR 55158 - Approval of Noise Compatibility Program for Lambert-St. Louis International Airport, St. Louis, MO

Science.gov (United States)

2011-09-06

... Program for Lambert-St. Louis International Airport, St. Louis, MO AGENCY: Federal Aviation Administration... noise compatibility program submitted by the St. Louis Airport Authority under the provisions of 49 U.S...''). On April 5, 2011, the FAA determined that the noise exposure maps submitted by the St. Louis Airport...

76 FR 33763 - Findings of Misconduct in Science/Research Misconduct

Science.gov (United States)

2011-06-09

..., Ph.D., St. Jude Children's Research Hospital: Based on the findings of an investigation report by St... oversight review, ORI found that Philippe Bois, Ph.D., former postdoctoral fellow, Department of Biochemistry, St. Jude, engaged in misconduct in science and research misconduct in research funded by National...

3rd International Meeting for Researchers in Materials and Plasma Technology (IMRMPT) and 1st Symposium on Nanoscience and Nanotechnology

International Nuclear Information System (INIS)

2016-01-01

These proceedings present the written contributions of the participants of the 3rd International Meeting for Researchers in Materials and Plasma Technology (3rd IMRMPT) and the 1st Symposium on Nanoscience and Nanotechnology which was held from 4 to May 9, 2015 at the Dann Carlton Hotel Bucaramanga, Colombia, organized by the faculty of science of the Universidad Industrial de Santander (UIS) and the basic science department of the Universidad Pontificia Bolivariana. This was the third version of biennial meetings that began in 2011. The five-day scientific program of the 3rd IMRMPT consisted of 24 Magisterial Conferences, 70 Oral Presentations, 185 Poster Presentations, 3 Courses and 1 Discussion Panel with the participation of undergraduate and graduate students, professors, researchers and entrepreneurs from Colombia, Russia, Germany, France, Spain, England, United States, Mexico, Argentina, Uruguay, Brazil, Venezuela, among others. Moreover, the objective of IMRMPT was to bring together national and international researchers in order to establish a network of scientific cooperation with a global impact in the area of the science and the technology of materials; to promote the exchange of creative ideas and the effective transfer of scientific knowledge, from fundamental research to innovation applied to industrial solutions and to advances in the development of new research allowing to increase the lifetime of the materials used in the industry by means of efficient transference of the knowledge between sectors academia and industry. The topics covered in the 3rd IMRMPT include New Materials, Surface Physics, Structural Integrity, Renewable Energy, Online Process Control, Non Destructive Evaluation, Characterization of Materials, Laser and Hybrid Processes, Thin Films and Nanomaterials, Surface Hardening Processes, Wear and Corrosion/Oxidation, Plasma Applications and Technologies, Modelling, Simulation and Diagnostics, Biomedical Coatings, Surface Treatments

The spread of KPC-producing Enterobacteriaceae in Spain: WGS analysis of the emerging high-risk clones of Klebsiella pneumoniae ST11/KPC-2, ST101/KPC-2 and ST512/KPC-3.

Science.gov (United States)

Oteo, Jesús; Pérez-Vázquez, María; Bautista, Verónica; Ortega, Adriana; Zamarrón, Pilar; Saez, David; Fernández-Romero, Sara; Lara, Noelia; Ramiro, Raquel; Aracil, Belén; Campos, José

2016-12-01

We analysed the microbiological traits and population structure of KPC-producing Enterobacteriaceae isolates collected in Spain between 2012 and 2014. We also performed a comparative WGS analysis of the three major KPC-producing Klebsiella pneumoniae clones detected. Carbapenemase and ESBL genes were sequenced. The Institut Pasteur MLST scheme was used. WGS data were used to construct phylogenetic trees, to identify the determinants of resistance and to de novo assemble the genome of one representative isolate of each of the three major K. pneumoniae clones. Of the 2443 carbapenemase-producing Enterobacteriaceae isolates identified during the study period, 111 (4.5%) produced KPC. Of these, 81 (73.0%) were K. pneumoniae and 13 (11.7%) were Enterobacter cloacae. Three major epidemic clones of K. pneumoniae were identified: ST11/KPC-2, ST101/KPC-2 and ST512/KPC-3. ST11/KPC-2 differed from ST101/KPC-2 and ST512/KPC-3 by 27 819 and 6924 SNPs, respectively. ST101/KPC-2 differed from ST512/KPC-3 by 28 345 SNPs. Nine acquired resistance genes were found in ST11/KPC-2, 11 in ST512/KPC-3 and 13 in ST101/KPC-2. ST101/KPC-2 had the highest number of virulence genes (20). An 11 bp deletion at the end of the mgrB sequence was the cause of colistin resistance in ST512/KPC-3. KPC-producing Enterobacteriaceae are increasing in Spain. Most KPC-producing K. pneumoniae isolates belonged to only five clones: ST11 and ST512 caused interregional spread, ST101 caused regional spread and ST1961 and ST678 produced independent hospital outbreaks. ST101/KPC-2 had the highest number of resistance and virulence genes. ST101/KPC-2 and ST512/KPC-3 were recently implicated in the spread of KPC in Italy. © The Author 2016. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Team Danmarks støttekoncept

DEFF Research Database (Denmark)

Storm, Rasmus K.

Evaluering af Team Danmarks støttekoncept 2005-2008 med omfattende analyser af Team Danmarks virke, dets støttekoncept og de samarbejdsrelationer med specialforbund, udøvere, politisk valgte ledere, trænere mv., som udmøntningen af støttekonceptet forudsætter. Herunder analyse af...

Research universities for the 21st century

Energy Technology Data Exchange (ETDEWEB)

Gover, J. [Sandia National Labs., Albuquerque, NM (United States); Huray, P.G. [Univ. of South Carolina, Columbia, SC (United States)

1998-05-01

The `public outcomes` from research universities are educated students and research that extends the frontiers of knowledge. Measures of these `public outcomes` are inadequate to permit either research or education consumers to select research universities based on quantitative performance data. Research universities annually spend over $20 billion on research; 60% of these funds are provided by Federal sources. Federal funding for university research has recently grown at an annual rate near 6% during a time period when other performers of Federal research have experienced real funding cuts. Ten universities receive about 25% of the Federal funds spent on university research. Numerous studies of US research universities are reporting storm clouds. Concerns include balancing research and teaching, the narrow focus of engineering education, college costs, continuing education, and public funding of foreign student education. The absence of research on the `public outcomes` from university research results in opinion, politics, and mythology forming the basis of too many decisions. Therefore, the authors recommend studies of other nations` research universities, studies of various economic models of university research, analysis of the peer review process and how well it identifies the most capable research practitioners and at what cost, and studies of research university ownership of intellectual property that can lead to increased `public outcomes` from publicly-funded research performed by research universities. They advocate two practices that could increase the `public outcomes` from university research. These are the development of science roadmaps that link science research to `public outcomes` and `public outcome` metrics. Changes in the university research culture and expanded use of the Internet could also lead to increased `public outcomes`. They recommend the use of tax incentives to encourage companies to develop research partnerships with research

Hydrogeology and ground-water flow of the drift and Platteville aquifer system, St Louis Park, Minnesota

Science.gov (United States)

Lindgren, R.J.

1995-01-01

Three aquifers and two confining units have been delineated within the drift underlying the area near the site of a former coal-tar distillation and wood-preserving plant in St. Louis Park, Minnesota. The hydrogeologic units of the drift, in descending order, are the upper drift aquifer, the upper drift confining unit, the middle drift aquifer, the lower drift confining unit. and the lower drift aquifer. A contamination plume consisting of coal-tar derivatives exists in the drift aquifers and in the Platteville aquifer underlying the southern part of the plant site and areas to the south and east of the plant site.

Inernational research in health care management: its need in the 21st century, methodological challenges, ethical issues, pitfalls, and practicalities.

Science.gov (United States)

Buttigieg, Sandra C; Rathert, Cheryl; D'Aunno, Thomas A; Savage, Grant T

2015-01-01

This commentary argues in favor of international research in the 21st century. Advances in technology, science, communication, transport, and infrastructure have transformed the world into a global village. Industries have increasingly adopted globalization strategies. Likewise, the health sector is more internationalized whereby comparisons between diverse health systems, international best practices, international benchmarking, cross-border health care, and cross-cultural issues have become important subjects in the health care literature. The focus has now turned to international, collaborative, cross-national, and cross-cultural research, which is by far more demanding than domestic studies. In this commentary, we explore the methodological challenges, ethical issues, pitfalls, and practicalities within international research and offer possible solutions to address them. The commentary synthesizes contributions from four scholars in the field of health care management, who came together during the annual meeting of the Academy of Management to discuss with members of the Health Care Management Division the challenges of international research. International research is worth pursuing; however, it calls for scholarly attention to key methodological and ethical issues for its success. This commentary addresses salient issues pertaining to international research in one comprehensive account.

Ocular Toxicity Profile of ST-162 and ST-168 as Novel Bifunctional MEK/PI3K Inhibitors.

Science.gov (United States)

Smith, Andrew; Pawar, Mercy; Van Dort, Marcian E; Galbán, Stefanie; Welton, Amanda R; Thurber, Greg M; Ross, Brian D; Besirli, Cagri G

2018-04-30

ST-162 and ST-168 are small-molecule bifunctional inhibitors of MEK and PI3K signaling pathways that are being developed as novel antitumor agents. Previous small-molecule and biologic MEK inhibitors demonstrated ocular toxicity events that were dose limiting in clinical studies. We evaluated in vitro and in vivo ocular toxicity profiles of ST-162 and ST-168. Photoreceptor cell line 661W and adult retinal pigment epithelium cell line ARPE-19 were treated with increasing concentrations of bifunctional inhibitors. Western blots, cell viability, and caspase activity assays were performed to evaluate MEK and PI3K inhibition and dose-dependent in vitro toxicity, and compared with monotherapy. In vivo toxicity profile was assessed by intravitreal injection of ST-162 and ST-168 in Dutch-Belted rabbits, followed by ocular examination and histological analysis of enucleated eyes. Retinal cell lines treated with ST-162 or ST-168 exhibited dose-dependent inhibition of MEK and PI3K signaling. Compared with inhibition by monotherapies and their combinations, bifunctional inhibitors demonstrated reduced cell death and caspase activity. In vivo, both bifunctional inhibitors exhibited a more favorable toxicity profile when compared with MEK inhibitor PD0325901. Novel MEK and PI3K bifunctional inhibitors ST-162 and ST-168 demonstrate favorable in vitro and in vivo ocular toxicity profiles, supporting their further development as potential therapeutic agents targeting multiple aggressive tumors.

St. John's Wort (image)

Science.gov (United States)

The herb St. John's Wort is believed to be helpful in relieving mild to moderate depression, but should only be taken under a physician's supervision. St. John's Wort may clash with other medications or ...

ACHP | News | St. Elizabeths Programmatic Agreement Signed

Science.gov (United States)

Search skip specific nav links Home arrow News arrow St. Elizabeths Programmatic Agreement Signed St redevelopment of the St. Elizabeths West Campus, which is part of the St. Elizabeths National Historic Landmark this project, due to the historic significance of the NHL. GSA's client for the St. Elizabeths

Behavioral Response Research Evaluation Workshop (BRREW)

Science.gov (United States)

2015-09-30

Len Thomas & Catriona Harris Centre for Research into Ecological and Environmental Modelling (CREEM) University of St Andrews St Andrews , UK...Specifically Dr. Hans Slabbekoorn (University of Leiden), Professor Vincent Janik (University of St Andrews ) and Professor Douglas Wartzok (Florida

Alcohol use by undergraduate students on their 21st birthday: predictors of actual consumption, anticipated consumption, and normative beliefs.

Science.gov (United States)

Day-Cameron, Jennifer M; Muse, Lauren; Hauenstein, Jennifer; Simmons, Lisa; Correia, Christopher J

2009-12-01

Recent research has identified celebration of a 21st birthday as an environmental event during which many college students engage in risky levels of alcohol consumption. The current study examined the relationship between personality and different aspects of alcohol use during 21st birthday celebrations: actual amount consumed for those who had turned 21, anticipated amount consumed for those under the age of 21, and normative beliefs regarding the amount other students consume on their 21st birthdays. Sensation seeking and impulsivity both displayed significant bivariate relationships with all three aspects of 21st birthday drinking. Personality traits did not contribute unique variance to actual 21st birthday drinking after the effects of typical alcohol consumption were accounted for in the models. Impulsivity contributed unique variance to models accounting for anticipated drinking and normative beliefs. Additional research is necessary to better understand the role personality variables play on alcohol consumption during 21st birthday celebrations. Copyright 2009 APA

First genome report on novel sequence types of Neisseria meningitidis: ST12777 and ST12778.

Science.gov (United States)

Veeraraghavan, Balaji; Lal, Binesh; Devanga Ragupathi, Naveen Kumar; Neeravi, Iyyan Raj; Jeyaraman, Ranjith; Varghese, Rosemol; Paul, Miracle Magdalene; Baskaran, Ashtawarthani; Ranjan, Ranjini

2018-03-01

Neisseria meningitidis is an important causative agent of meningitis and/or sepsis with high morbidity and mortality. Baseline genome data on N. meningitidis, especially from developing countries such as India, are lacking. This study aimed to investigate the whole genome sequences of N. meningitidis isolates from a tertiary care centre in India. Whole-genome sequencing was performed using an Ion Torrent™ Personal Genome Machine™ (PGM) with 400-bp chemistry. Data were assembled de novo using SPAdes Genome Assembler v.5.0.0.0. Sequence annotation was performed through PATRIC, RAST and the NCBI PGAAP server. Downstream analysis of the isolates was performed using the Center for Genomic Epidemiology databases for antimicrobial resistance genes and sequence types. Virulence factors and CRISPR were analysed using the PubMLST database and CRISPRFinder, respectively. This study reports the whole genome shotgun sequences of eight N. meningitidis isolates from bloodstream infections. The genome data revealed two novel sequence types (ST12777 and ST12778), along with ST11, ST437 and ST6928. The virulence profile of the isolates matched their sequence types. All isolates were negative for plasmid-mediated resistance genes. To the best of our knowledge, this is the first report of ST11 and ST437 N. meningitidis isolates in India along with two novel sequence types (ST12777 and ST12778). These results indicate that the sequence types circulating in India are diverse and require continuous monitoring. Further studies strengthening the genome data on N. meningitidis are required to understand the prevalence, spread, exact resistance and virulence mechanisms along with serotypes. Copyright © 2017 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.

78 FR 7663 - SLR; 2013 International Rolex Regatta; St. Thomas Harbor; St. Thomas, U.S. Virgin Islands

Science.gov (United States)

2013-02-04

... 1625-AA08 SLR; 2013 International Rolex Regatta; St. Thomas Harbor; St. Thomas, U.S. Virgin Islands... special local regulations on the waters of St. Thomas Harbor in St. Thomas, U. S. Virgin Islands during... 5 p.m., Monday through Friday, except federal holidays. The telephone number is 202-366-9329. See...

Bioethanol Production by Calcium Alginate-Immobilised St1 Yeast System: Effects of Size of Beads, Ratio and Concentration

Directory of Open Access Journals (Sweden)

Masniroszaime Md Zain

2011-12-01

Full Text Available Immobilized yeast-cell technology posses several advantages in bioethanol production due to its potential to increase the ethanol yield by eliminating unit process used. Thus, process expenses in cell recovery and reutilization can be minimised. The aim of this study is to investigate the influence of three parameters (substrate concentrations, size of alginate beads and ratio of volume of beads to volume of medium on local isolated yeast (ST1 which immobilized using calcium alginate fermentation system. The most affected ethanol production by calcium alginate-immobilised ST1 yeast system were ratio of volume of the beads to the volume of substrate and concentration of LBS. Highest theoretical yield, 78% was obtained in ST1-alginate beads with the size of beads 0.5cm, ratio volume of beads to the volume of LBS media 0.4 and 150g/l concentration of LBS.ABSTRAK: Teknologi sel yis pegun memiliki beberapa kelebihan dalam penghasilan bioetanol kerana ia berpotensi meningkatkan pengeluaran etanol dengan menyingkirkan unit proses yang digunakan. Maka, proses pembiayaan dalam perolehan sel dan penggunaan semula boleh dikurangkan. Tujuan kajian ini adalah untuk mengkaji pengaruh tiga parameter (kepekatan substrat, saiz manik alginat dan nisbah isipadu manik terhadap isipadu bahantara ke atas sel tempatan terasing (local isolated yeast (ST1 yang dipegun menggunakan sistem penapaian kalsium alginat. Penghasilan etanol yang paling berkesan dengan menggunakan sistem yis ST1 kalsium alginat-pegun adalah dengan kadar nisbah isipadu manik terhadap isipadu substrat dan kepekatan LBS. Kadar hasil teori tertinggi iaitu 78% didapati menerusi manik alginat-ST1 dengan saiz manik 0.5cm, nisbah isipadu 0.4 terhadap perantara LBS dan kepekatan LBS sebanyak 150g/l. Normal 0 false false false EN-US X-NONE X-NONE

Isolation and characterization of styrene metabolism genes from styrene-assimilating soil bacteria Rhodococcus sp. ST-5 and ST-10.

Science.gov (United States)

Toda, Hiroshi; Itoh, Nobuya

2012-01-01

Styrene metabolism genes were isolated from styrene-assimilating bacteria Rhodococcus sp. ST-5 and ST-10. Strain ST-5 had a gene cluster containing four open reading frames which encoded styrene degradation enzymes. The genes showed high similarity to styABCD of Pseudomonas sp. Y2. On the other hand, strain ST-10 had only two genes which encoded styrene monooxygenase and flavin oxidoreductase (styAB). Escherichia coli transformants possessing the sty genes of strains ST-5 and ST-10 produced (S)-styrene oxide from styrene, indicating that these genes function as styrene degradation enzymes. Metabolite analysis by resting-cell reaction with gas chromatography-mass spectrometry revealed that strain ST-5 converts styrene to phenylacetaldehyde via styrene oxide by styrene oxide isomerase (styC) reaction. On the other hand, strain ST-10 lacked this enzyme, and thus accumulated styrene oxide as an intermediate. HPLC analysis showed that styrene oxide was spontaneously isomerized to phenylacetaldehyde by chemical reaction. The produced phenylacetaldehyde was converted to phenylacetic acid (PAA) in strain ST-10 as well as in strain ST-5. Furthermore, phenylacetic acid was converted to phenylacetyl-CoA by the catalysis of phenylacetate-CoA ligase in strains ST-5 and ST-10. This study proposes possible styrene metabolism pathways in Rhodococcus sp. strains ST-5 and ST-10. Copyright © 2011 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

Pet Care Teaching Unit: 1st-3rd Grades.

Science.gov (United States)

Peninsula Humane Society, San Mateo, CA.

Activities in this unit are designed to familiarize primary grade students with the responsibilities involved in pet ownership. Teaching plans are provided for a total of 12 lessons involving social studies, language arts, math, and health sciences. Activities adaptable for readers and non-readers focus on pet overpopulation, care of pets when…

Intraurban Spatiotemporal Variability of Ambient Air Pollutants across Metropolitan St. Louis

Science.gov (United States)

Du, Li

Ambient air monitoring networks have been established in the United States since the 1970s to comply with the Clean Air Act. The monitoring networks are primarily used to determine compliance but also provide substantive support to air quality management and air quality research including studies on health effects of air pollutants. The Roxana Air Quality Study (RAQS) was conducted at the fenceline of a petroleum refinery in Roxana, Illinois. In addition to providing insights into air pollutant impacts from the refinery, these measurements increased the St. Louis area monitoring network density for gaseous air toxics and fine particulate matter (PM2.5) speciation and thus provided an opportunity to examine intraurban spatiotemporal variability for these air quality parameters. This dissertation focused on exploring and assessing aspects of ambient air pollutant spatiotemporal variability in the St. Louis area from three progressively expanded spatial scales using a suite of methods and metrics. RAQS data were used to characterize air quality conditions in the immediate vicinity of the petroleum refinery. For example, PM2.5 lanthanoids were used to track impacts from refinery fluidized bed catalytic cracker emissions. RAQS air toxics data were interpreted by comparing to network data from the Blair Street station in the City of St. Louis which is a National Air Toxics Trends Station. Species were classified as being spatially homogeneous (similar between sites) or heterogeneous (different between sites) and in the latter case these differences were interpreted using surface winds data. For PM 2.5 species, there were five concurrently operating sites in the St. Louis area - including the site in Roxana - which are either formally part of the national Chemical Speciation Network (CSN) or rigorously follow the CSN sampling and analytical protocols. This unusually large number of speciation sites for a region the size of St. Louis motivated a detailed examination of

Bimetal cup hydroforming of Al/St and Cu/St composites: Adaptive finite element analysis and experimental study

Energy Technology Data Exchange (ETDEWEB)

Hashemi, Abbas; Gollo, Mohammad Hoseinpour [Shahid Rajaee Teacher Training University, Tehran (Iran, Islamic Republic of); Seyedkashi, S. M. [University of Birjand, Birjand (Iran, Islamic Republic of)

2016-05-15

An adaptive Finite element analysis (FEA) was proposed in this paper for the industrial design of bimetal conical-cylindrical cup hydroforming. Forming circumstances for the perfect and imperfect parts were concluded through adaptive FEA using the ANSYS parametric design language. Effective parameters, including pressure loading path, layer placement order, and thickness ratio, were investigated for hydroforming of Al/St and Cu/St composite sheets. Experimental tests were implemented to validate adaptive finite element results. Rupture failure upon the pressure path occurred on the contact area between the blank and punch tip radius at low pressures and on the transition area of the conical-cylindrical portion at high pressures. The proposed method is applicable for any cylindrical, conical, or cylindrical/conical shapes with different materials and dimensions. Therefore, this method is beneficial as a practical design tool for engineers and researchers working in the process design of hydroformed shell products.

Building visual identity of scientific and research units and the role of visualization in cooperation with business

Directory of Open Access Journals (Sweden)

Alfreda Kamińska

2014-12-01

Full Text Available The need for commercialization of scientific research leads to the necessity of changing the orientation of scientific-research units to marketing orientation, which is characterized by, among others, conducting research aimed at learning the clients’ needs and building better communication with the recipients. What is an important element of a unit’s marketing communication is its visual identity system, which the recipients use to build their opinion and their picture of the unit. The goal of this article is an attempt to define the key rules of designing visual identity of scientific and research institutions, as well as presenting the role of visualization in their cooperation with business. In the article the notions of image, identity, corporate identity and visual identity are subject to analysis. The article also presents the significance of visualization in the functioning of research and scientific units, elements of visual identity system and the rules of designing visual identity of scientific and research institutions. An analysis of chosen research-scientific units was carried out with regard to visualization.

Perancangan Aplikasi Customer Relationship Management untuk Meningkatkan Pelayanan pada Rumah Sakit St. Carolus

Directory of Open Access Journals (Sweden)

Joni Suhartono

2015-06-01

Full Text Available Research aims to create a draft of application based on customer relationship management (CRM toimprove services on St carolus hospital in terms of criticism-suggestions, to create scheduling events and patient schedule for second time which is still less control. Research used survey, interview the parties concerned, aswell as analyzing the systems running on St Carolus hospital. Results of the research are application design that helps to improve the quality of the hospital service to the patient, application design that helps management in holding the event, and managing the input given by the visitor at ease. In conclusion, the application designhelps manage criticism and suggestions, make events, and intertwine relations with patients after medication or treatment.

Identifying 21st Century Capabilities

Science.gov (United States)

Stevens, Robert

2012-01-01

What are the capabilities necessary to meet 21st century challenges? Much of the literature on 21st century skills focuses on skills necessary to meet those challenges associated with future work in a globalised world. The result is a limited characterisation of those capabilities necessary to address 21st century social, health and particularly…

Ethnographic research into nursing in acute adult mental health units: a review.

Science.gov (United States)

Cleary, Michelle; Hunt, Glenn E; Horsfall, Jan; Deacon, Maureen

2011-01-01

Acute inpatient mental health units are busy and sometimes chaotic settings, with high bed occupancy rates. These settings include acutely unwell patients, busy staff, and a milieu characterised by unpredictable interactions and events. This paper is a report of a literature review conducted to identify, analyse, and synthesize ethnographic research in adult acute inpatient mental health units. Several electronic databases were searched using relevant keywords to identify studies published from 1990-present. Additional searches were conducted using reference lists. Ethnographic studies published in English were included if they investigated acute inpatient care in adult settings. Papers were excluded if the unit under study was not exclusively for patients in the acute phase of their mental illness, or where the original study was not fully ethnographic. Ten research studies meeting our criteria were found (21 papers). Findings were grouped into the following overarching categories: (1) Micro-skills; (2) Collectivity; (3) Pragmatism; and (4) Reframing of nursing activities. The results of this ethnographic review reveal the complexity, patient-orientation, and productivity of some nursing interventions that may not have been observed or understood without the use of this research method. Additional quality research should focus on redefining clinical priorities and philosophies to ensure everyday care is aligned constructively with the expectations of stakeholders and is consistent with policy and the realities of the organisational setting. We have more to learn from each other with regard to the effective nursing care of inpatients who are acutely disturbed.

77 FR 46681 - Advisory Committee on Biotechnology and 21st Century Agriculture; Notice of Meeting

Science.gov (United States)

2012-08-06

...;and investigations, committee meetings, agency decisions and rulings, #0;delegations of authority... Biotechnology and 21st Century Agriculture; Notice of Meeting AGENCY: Agricultural Research Service, USDA... Biotechnology and 21st Century Agriculture (AC21). DATES: The meeting dates are August 27-28, 2012, 8:30 a.m. to...

In Vitro Toxicity testing in the 21st Century

Directory of Open Access Journals (Sweden)

Erwin L Roggen

2011-02-01

Full Text Available The National Research Council (NRC article Toxicity Testing in the 21st Century: A vision and A Strategy (National Research Council, 2007 was written to bring attention to the application of scientific advances for use in toxicity tests so that chemicals can be tested in a more time and cost efficient manner while providing a more relevant and mechanistic insight into the toxic potential of a compound.Development of tools for in vitro toxicity testing constitutes an important activity of this vision and contributes to the provision of test systems as well as data that are essential for the development of computer modelling tools for e.g. system biology, physiologically-based modelling. This article intends to highlight some of the issues that have to be addressed in order to make in vitro toxicity testing a reality in the 21st century.

The macroeconomic factors impact on the Level of Food Expenditure of St. Petersburg Residents

OpenAIRE

Bulatova Anastasiia

2016-01-01

The topic of this research is the impact of the macroeconomic factors on food spending residents of St. Petersburg. The problem of the study is the ambiguity of the food sanctions impact on the consumer spending on food. The aim of the work are the trend analyze in the level of food spending in St. Petersburg since the first quarter of 2007 to the third quarter 2015, and the identifying of factors influencing these food waste. St. Petersburg was chosen because it is a city with a large popula...

The aging of biomedical research in the United States.

Directory of Open Access Journals (Sweden)

Kirstin R W Matthews

Full Text Available In the past 30 years, the average age of biomedical researchers has steadily increased. The average age of an investigator at the National Institutes of Health (NIH rose from 39 to 51 between 1980 and 2008. The aging of the biomedical workforce was even more apparent when looking at first-time NIH grantees. The average age of a new investigator was 42 in 2008, compared to 36 in 1980. To determine if the rising barriers at NIH for entry in biomedical research might impact innovative ideas and research, we analyzed the research and publications of Nobel Prize winners from 1980 to 2010 to assess the age at which their pioneering research occurred. We established that in the 30-year period, 96 scientists won the Nobel Prize in medicine or chemistry for work related to biomedicine, and that their groundbreaking research was conducted at an average age of 41-one year younger than the average age of a new investigator at NIH. Furthermore, 78% of the Nobel Prize winners conducted their research before the age of 51, the average age of an NIH principal investigator. This suggested that limited access to NIH might inhibit research potential and novel projects, and could impact biomedicine and the next generation scientists in the United States.

Capitalism and the New World Order of the 21st Century Age | Ugwu ...

African Journals Online (AJOL)

The Post-Cold War Capitalists'-based Vision here being called a 'New World Order', especially, in its current practices, as it has been imposed on the rest of the world by the G8 nations and assisted by the World Bank, IMF, United Nations, WTO and NATO, is a 21st Century Imperialist Rule constantly being communicated to ...

Forest carbon management in the United States: 1600-2100

Science.gov (United States)

Richard A. Birdsey; Kurt Pregitzer; Alan Lucier

2006-01-01

This paper reviews the effects of past forest management on carbon stocks in the United States, and the challenges for managing forest carbon resources in the 21st century. Forests in the United States were in approximate carbon balance with the atmosphere from 1600-1800. Utilization and land clearing caused a large pulse of forest carbon emissions during the 19th...

Dinosaur or Phoenix: Nuclear Bombers in the 21st Century

Science.gov (United States)

2010-04-12

REPORT DATE 02-04-10 2. REPORT TYPE Master’s Thesis 3. DATES COVERED 31-07-09 to 16-06-10 4. TITLE AND SUBTITLE Dinosaur or Phoenix: Nuclear...WARFIGHTING SCHOOL DINOSAUR OR PHOENIX: NUCLEAR BOMBERS IN THE 21ST CENTURY by John W. Morehead Colonel, United States Air Force A paper...can argue Secretary Gates’ decision to halt development of a follow-on bomber indicates the DOD views nuclear bombers as dinosaurs no longer needed as

Data-to-Decisions S&T Priority Initiative

Science.gov (United States)

2011-11-08

Decisions S&T Priority Initiative Dr. Carey Schwartz PSC Lead Office of Naval Research NDIA Disruptive Technologies Conference November 8-9, 2011...DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY NOTES Presented at the NDIA Disruptive ... Technologies Conference, November 8,-9, 2011,Washington, DC 14. ABSTRACT 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT

Closing Symposium of the DFG Research Unit FOR 1066

CERN Document Server

Niehuis, Reinhard; Kroll, Norbert; Behrends, Kathrin

2016-01-01

The book reports on advanced solutions to the problem of simulating wing and nacelle stall, as presented and discussed by internationally recognized researchers at the Closing Symposium of the DFG Research Unit FOR 1066. Reliable simulations of flow separation on airfoils, wings and powered engine nacelles at high Reynolds numbers represent great challenges in defining suitable mathematical models, computing numerically accurate solutions and providing comprehensive experimental data for the validation of numerical simulations. Additional problems arise from the need to consider airframe-engine interactions and inhomogeneous onset flow conditions, as real aircraft operate in atmospheric environments with often-large distortions. The findings of fundamental and applied research into these and other related issues are reported in detail in this book, which targets all readers, academics and professionals alike, interested in the development of advanced computational fluid dynamics modeling for the simulation of...

If F(ST) does not measure neutral genetic differentiation, then comparing it with Q(ST) is misleading. Or is it?

Science.gov (United States)

Edelaar, Pim; Björklund, Mats

2011-05-01

The comparison between neutral genetic differentiation (F(ST) ) and quantitative genetic differentiation (Q(ST) ) is commonly used to test for signatures of selection in population divergence. However, there is an ongoing discussion about what F(ST) actually measures, even resulting in some alternative metrics to express neutral genetic differentiation. If there is a problem with F(ST) , this could have repercussions for its comparison with Q(ST) as well. We show that as the mutation rate of the neutral marker increases, F(ST) decreases: a higher within-population heterozygosity (He) yields a lower F(ST) value. However, the same is true for Q(ST) : a higher mutation rate for the underlying QTL also results in a lower Q(ST) estimate. The effect of mutation rate is equivalent in Q(ST) and F(ST) . Hence, the comparison between Q(ST) and F(ST) remains valid, if one uses neutral markers whose mutation rates are not too high compared to those of quantitative traits. Usage of highly variable neutral markers such as hypervariable microsatellites can lead to serious biases and the incorrect inference that divergent selection has acted on populations. Much of the discussion on F(ST) seems to stem from the misunderstanding that it measures the differentiation of populations, whereas it actually measures the fixation of alleles. In their capacity as measures of population differentiation, Hedrick's G'(ST) and Jost's D reach their maximum value of 1 when populations do not share alleles even when there remains variation within populations, which invalidates them for comparisons with Q(ST) . © 2011 Blackwell Publishing Ltd.

Volcano ecology: flourishing on the flanks of Mount St. Helens

Science.gov (United States)

Rhonda Mazza; Charlie Crisafulli

2016-01-01

Mount St. Helens’ explosive eruption on May 18, 1980, was a pivotal moment in the field of disturbance ecology. The subsequent sustained, integrated research effort has shaped the development of volcano ecology, an emerging field of focused research. Excessive heat, burial, and impact force are some of the disturbance mechanisms following an eruption. They are also...

The Use of Importance Measures for Quantification of Multi-unit Risk

Energy Technology Data Exchange (ETDEWEB)

Jang, Seung-Cheol; Lim, Ho-Gon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2015-10-15

In this paper, we focus on the quantification of the multi-unit accident sequences frequencies, i.e., conditional core damage probability (CCDP) for a MUI from the SUR model. The paper proposes a method for the estimation of the r-units CCDP considered the interunit dependency, using importance measures. Note that the 1{sup st} and 2{sup nd} terms in the left hand side of the equation have different units of risk measure, i.e., reactor operating year and site operating year, respectively. The total risk of multi-unit reactor accidents concurred by the independent accident sequences each single-unit (the 1{sup st} term in the right-hand side of the Equation 1) can approximate the sum of n single-unit risk conservatively. It corresponds to the traditional multi-unit risk profile concept having used since post-PSA era. Simultaneously, the Equation 1 represent that multi-unit risk within a site with n units has been underestimated as much as the amount of the 2{sup nd} term (MUR by multi-unit initiators), which consists of three parts: 1) the frequency estimation of a MUI, , 2) the quantification of the multi-unit accident sequences frequencies for a MUI, , and 3) the multi-unit consequence analysis for a MUI. The paper proposes a method for the estimation of the r-units CCDP considered the inter-unit dependency, using importance measures. It can facilitate the treatment of the inter-unit dependencies in the multi-unit risk model and can give more comprehensive and more practicable technical platform for estimating multi-unit site risk.

The Use of Importance Measures for Quantification of Multi-unit Risk

International Nuclear Information System (INIS)

Jang, Seung-Cheol; Lim, Ho-Gon

2015-01-01

In this paper, we focus on the quantification of the multi-unit accident sequences frequencies, i.e., conditional core damage probability (CCDP) for a MUI from the SUR model. The paper proposes a method for the estimation of the r-units CCDP considered the interunit dependency, using importance measures. Note that the 1 st and 2 nd terms in the left hand side of the equation have different units of risk measure, i.e., reactor operating year and site operating year, respectively. The total risk of multi-unit reactor accidents concurred by the independent accident sequences each single-unit (the 1 st term in the right-hand side of the Equation 1) can approximate the sum of n single-unit risk conservatively. It corresponds to the traditional multi-unit risk profile concept having used since post-PSA era. Simultaneously, the Equation 1 represent that multi-unit risk within a site with n units has been underestimated as much as the amount of the 2 nd term (MUR by multi-unit initiators), which consists of three parts: 1) the frequency estimation of a MUI, , 2) the quantification of the multi-unit accident sequences frequencies for a MUI, , and 3) the multi-unit consequence analysis for a MUI. The paper proposes a method for the estimation of the r-units CCDP considered the inter-unit dependency, using importance measures. It can facilitate the treatment of the inter-unit dependencies in the multi-unit risk model and can give more comprehensive and more practicable technical platform for estimating multi-unit site risk

In vitro efficacy of ST246 against smallpox and monkeypox.

Science.gov (United States)

Smith, Scott K; Olson, Victoria A; Karem, Kevin L; Jordan, Robert; Hruby, Dennis E; Damon, Inger K

2009-03-01

Since the eradication of smallpox and the cessation of routine childhood vaccination for smallpox, the proportion of the world's population susceptible to infection with orthopoxviruses, such as variola virus (the causative agent of smallpox) and monkeypox virus, has grown substantially. In the United States, the only vaccines for smallpox licensed by the Food and Drug Administration (FDA) have been live virus vaccines. Unfortunately, a substantial number of people cannot receive live virus vaccines due to contraindications. Furthermore, no antiviral drugs have been fully approved by the FDA for the prevention or treatment of orthopoxvirus infection. Here, we show the inhibitory effect of one new antiviral compound, ST-246, on the in vitro growth properties of six variola virus strains and seven monkeypox virus strains. We performed multiple assays to monitor the cytopathic effect and to evaluate the reduction of viral progeny production and release in the presence of the compound. ST-246 had 50% effective concentrations of ST-246 inhibits variola and monkeypox viruses similarly by reducing the production and release of enveloped orthopoxvirus and support the development of ST-246 as an antiviral therapeutic compound for the treatment of severe systemic orthopoxvirus infections.

An Overview of Research Infrastructure for Medieval Studies in the United States: Associations, Institutes, and Universities

Directory of Open Access Journals (Sweden)

Zan Kocher

2011-11-01

Full Text Available This overview of research infrastructure in the United States brieflymentions some institutes, universities, associations, conferences,sources of funding, types of courses, research databases, academicjournals and book publishers. It intends to make American medievalistresources better accessible to colleagues from other countries, and toencourage those who wish to study in the United States and those whoare using the Internet to seek printed or digital materials for theirteaching or research.

Salamander chytrid fungus (Batrachochytrium salamandrivorans) in the United States—Developing research, monitoring, and management strategies

Science.gov (United States)

Grant, Evan H. Campbell; Muths, Erin L.; Katz, Rachel A.; Canessa, Stefano; Adams, Michael J.; Ballard, Jennifer R.; Berger, Lee; Briggs, Cheryl J.; Coleman, Jeremy; Gray, Matthew J.; Harris, M. Camille; Harris, Reid N.; Hossack, Blake R.; Huyvaert, Kathryn P.; Kolby, Jonathan E.; Lips, Karen R.; Lovich, Robert E.; McCallum, Hamish I.; Mendelson, Joseph R.; Nanjappa, Priya; Olson, Deanna H.; Powers, Jenny G.; Richgels, Katherine L. D.; Russell, Robin E.; Schmidt, Benedikt R.; Spitzen-van der Sluijs, Annemarieke; Watry, Mary Kay; Woodhams, Douglas C.; White, C. LeAnn

2016-01-20

The recently (2013) identified pathogenic chytrid fungus, Batrachochytrium salamandrivorans (Bsal), poses a severe threat to the distribution and abundance of salamanders within the United States and Europe. Development of a response strategy for the potential, and likely, invasion of Bsal into the United States is crucial to protect global salamander biodiversity. A formal working group, led by Amphibian Research and Monitoring Initiative (ARMI) scientists from the U.S. Geological Survey (USGS) Patuxent Wildlife Research Center, Fort Collins Science Center, and Forest and Rangeland Ecosystem Science Center, was held at the USGS Powell Center for Analysis and Synthesis in Fort Collins, Colorado, United States from June 23 to June 25, 2015, to identify crucial Bsal research and monitoring needs that could inform conservation and management strategies for salamanders in the United States. Key findings of the workshop included the following: (1) the introduction of Bsal into the United States is highly probable, if not inevitable, thus requiring development of immediate short-term and long-term intervention strategies to prevent Bsal establishment and biodiversity decline; (2) management actions targeted towards pathogen containment may be ineffective in reducing the long-term spread of Bsal throughout the United States; and (3) early detection of Bsal through surveillance at key amphibian import locations, among high-risk wild populations, and through analysis of archived samples is necessary for developing management responses. Top research priorities during the preinvasion stage included the following: (1) deployment of qualified diagnostic methods for Bsal and establishment of standardized laboratory practices, (2) assessment of susceptibility for amphibian hosts (including anurans), and (3) development and evaluation of short- and long-term pathogen intervention and management strategies. Several outcomes were achieved during the workshop, including development

Outcome of Patients With Adenosine-Induced ST Segment Depression and Normal Myocardial Perfusion

International Nuclear Information System (INIS)

El-Refaei, S.; Selim, M.

2011-01-01

The aim of the present study was to determine the outcome of patients with normal MPS and adenosine-induced ST segment depression. A total of 1867 patients underwent adenosine Tc99m-tetrofosmin MPS in nuclear medicine unit in Saudi German Hospital, Saudi Arabia, between January 2004 and May 2008. Their ECGs were checked for ST segment depression during adenosine infusion. All patients with ≥ 1 mm horizontal or down-sloping ST segment depression or≥ 1.5 mm up-sloping ST segment depression were included in the study. Fifty-six patients met our inclusion criteria, of which 45 (80%) were females. During the follow-up period, a total of 15 of patients ended up doing coronary angiography, either for high clinical suspicion or following a second positive MPS performed 6-18 months after the first study. Seven of them were positive for coronary artery disease and were subsequently treated with revascularization procedure, and 8 returned either normal angiography or non-obstructive coronary artery disease. Male diabetic smoking patients were more prevalent and underwent revascularization. The patients were followed up for a mean of 22.8 ±7.8 months. No cardiac deaths or myocardial infarctions were reported. It could be concluded that adenosine-induced ST segment depression in patients with normal myocardial perfusion was a benign finding and did not increase the very low risk of cardiac events in those patients. However, male smokers and/or diabetics might need further investigation. This suggestion needs further evaluation

Calculating the Unit Cost Factors for Decommissioning Cost Estimation of the Nuclear Research Reactor

International Nuclear Information System (INIS)

Jeong, Kwan Seong; Lee, Dong Gyu; Jung, Chong Hun; Lee, Kune Woo

2006-01-01

The estimated decommissioning cost of nuclear research reactor is calculated by applying a unit cost factor-based engineering cost calculation method on which classification of decommissioning works fitted with the features and specifications of decommissioning objects and establishment of composition factors are based. Decommissioning cost of nuclear research reactor is composed of labor cost, equipment and materials cost. Labor cost of decommissioning costs in decommissioning works are calculated on the basis of working time consumed in decommissioning objects. In this paper, the unit cost factors and work difficulty factors which are needed to calculate the labor cost in estimating decommissioning cost of nuclear research reactor are derived and figured out.

New Challenges in 21st-Century Dance Education

Science.gov (United States)

Kassing, Gayle

2010-01-01

To become competent in today's society, individuals need multiliteracies. The 21st-century dancer needs to be an artist, choreographer, educator, and researcher who can meet challenges and make an impact within the profession, as well as across education, the arts, and society. As dance professionals assess how to utilize their resources better…

Marketing and 21 st Century Technological Challenges: The Need ...

African Journals Online (AJOL)

Marketing and 21 st Century Technological Challenges: The Need for Curricula Review. ... Journal of Research in National Development ... Marketing had over the years served the dominant function of bridging the gap between production and consumption through a conceptualized, well structured programme of academic ...

St. Thomas and St. John, U.S. Virgin Islands Coastal Digital Elevation Model

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The 1/3 arc-second St. Thomas and St. John, U.S. Virgin Islands Coastal Digital Elevation Model will be used to support NOAA's tsunami forecast system and for...

Outcomes by Mode of Transport of ST Elevation MI Patients in the United Arab Emirates

OpenAIRE

Callachan, Edward L.; Alsheikh-Ali, Alawi A.; Nair, Satish Chandrasekhar; Bruijns, Stevan; Wallis, Lee A.

2017-01-01

Introduction The purpose of this multicenter study was to assess differences in demographics, medical history, treatment times, and follow-up status among patients with ST-elevation myocardial infarction (STEMI), who were transported to the hospital by emergency medical services (EMS) or by private vehicle, or were transferred from other medical facilities. Methods This multicenter study involved the collection of both retrospective and prospective data from 455 patients admitted to four hosp...

The INTERGROWTH-21st Project Neurodevelopment Package: a novel method for the multi-dimensional assessment of neurodevelopment in pre-school age children.

Directory of Open Access Journals (Sweden)

Michelle Fernandes

Full Text Available BACKGROUND: The International Fetal and Newborn Growth Consortium for the 21st Century (INTERGROWTH-21st Project is a population-based, longitudinal study describing early growth and development in an optimally healthy cohort of 4607 mothers and newborns. At 24 months, children are assessed for neurodevelopmental outcomes with the INTERGROWTH-21st Neurodevelopment Package. This paper describes neurodevelopment tools for preschoolers and the systematic approach leading to the development of the Package. METHODS: An advisory panel shortlisted project-specific criteria (such as multi-dimensional assessments and suitability for international populations to be fulfilled by a neurodevelopment instrument. A literature review of well-established tools for preschoolers revealed 47 candidates, none of which fulfilled all the project's criteria. A multi-dimensional assessment was, therefore, compiled using a package-based approach by: (i categorizing desired outcomes into domains, (ii devising domain-specific criteria for tool selection, and (iii selecting the most appropriate measure for each domain. RESULTS: The Package measures vision (Cardiff tests; cortical auditory processing (auditory evoked potentials to a novelty oddball paradigm; and cognition, language skills, behavior, motor skills and attention (the INTERGROWTH-21st Neurodevelopment Assessment in 35-45 minutes. Sleep-wake patterns (actigraphy are also assessed. Tablet-based applications with integrated quality checks and automated, wireless electroencephalography make the Package easy to administer in the field by non-specialist staff. The Package is in use in Brazil, India, Italy, Kenya and the United Kingdom. CONCLUSIONS: The INTERGROWTH-21st Neurodevelopment Package is a multi-dimensional instrument measuring early child development (ECD. Its developmental approach may be useful to those involved in large-scale ECD research and surveillance efforts.

Radioimmunoimaging of human colon and gastric cancers xenografts by NCC-ST-439 and NCC-ST-433 monoclonal antibodies

International Nuclear Information System (INIS)

Nakamura, Kayoko; Tsukatani, Yasushi; Nishiguchi, Iku

1987-01-01

Both NCC-ST-439 and NCC-ST-433 are monoclonal antibodies raised against human gastric cancer (St-4) xenografts in nude mice. Imaging and localization experiments were performed by injecting I-125 labeled antibodies into nude mice bearing CO-4 (colon carcinoma) and H-111 (gastric carcinoma). There was uptake of NCC-ST-439 (polymer) into the CO-4, though it was not clearly visualized until 5 days post injection. By injecting NCC-ST-439 (monomer), CO-4 was better seen at day 3, while average accumulation into the tumors decreased compared with NCC-ST-439 (polymer). High radioactivities were observed in the liver and spleen, which was probably due to the immunocomplex with the antigen in the blood. NCC-ST-433 was selectively accumulated into the H-111 with tumor to blood ratio 7.8 at day 7, without significant uptake into the liver and spleen. Significant correlation was also found between the tumor uptake level of NCC-ST-433 and size of tumors. Excellent images of H-111 were obtained 3 days after the injection. NCC-ST-433 holds promise for the radioimmunodetection of gastric cancers. (author)

Draft Genome Sequences of Staphylococcus aureus AMRF1 (ST22) and AMRF2 (ST672), Ocular Methicillin-Resistant Isolates

KAUST Repository

Velusamy, Nithya

2014-03-20

Sequence type 22 (ST22) and ST672 are the two major emerging clones of community-acquired methicillin-resistant Staphylococcus aureus in India. ST672 strains were found to cause severe ocular infections. We report the draft genome sequences of two emerging strains of methicillin-resistant S. aureus, AMRF1 (ST22) and AMRF2 (ST672), isolated from patients with ocular infections.

Draft Genome Sequences of Staphylococcus aureus AMRF1 (ST22) and AMRF2 (ST672), Ocular Methicillin-Resistant Isolates

KAUST Repository

Velusamy, Nithya; Prakash, Logambiga; Neelamegam, Sivakumar; Antony, Aju; Prajna, Lalitha; Mohankumar, Vidyarani; Devarajan, Bharanidharan

2014-01-01

Sequence type 22 (ST22) and ST672 are the two major emerging clones of community-acquired methicillin-resistant Staphylococcus aureus in India. ST672 strains were found to cause severe ocular infections. We report the draft genome sequences of two emerging strains of methicillin-resistant S. aureus, AMRF1 (ST22) and AMRF2 (ST672), isolated from patients with ocular infections.

78 FR 16211 - Safety Zone, Corp. Event Finale UHC, St. Thomas Harbor; St. Thomas, U.S. Virgin Islands

Science.gov (United States)

2013-03-14

... 1625-AA00 Safety Zone, Corp. Event Finale UHC, St. Thomas Harbor; St. Thomas, U.S. Virgin Islands... establish a temporary safety zone on the waters of St. Thomas Harbor in St. Thomas, U.S. Virgin Islands... through Friday, except federal holidays. The telephone number is 202-366-9329. See the ``Public...

78 FR 23489 - Safety Zone; V.I. Carnival Finale, St. Thomas Harbor; St. Thomas, U.S.V.I.

Science.gov (United States)

2013-04-19

... waters of St. Thomas Harbor in St. Thomas, U.S. Virgin Islands during the V.I. Carnival Finale, a... through Friday, except Federal holidays. FOR FURTHER INFORMATION CONTACT: If you have questions on this... event. The event will be held on the waters of St. Thomas Harbor, St. Thomas, U. S. Virgin Islands...

78 FR 22778 - Safety Zone; Corp. Event Finale UHC, St. Thomas Harbor; St. Thomas, U.S.V.I.

Science.gov (United States)

2013-04-17

... waters of St. Thomas Harbor in St. Thomas, U.S. Virgin Islands during the Corp. Event Finale UHC, a.... and 5 p.m., Monday through Friday, except Federal holidays. FOR FURTHER INFORMATION CONTACT: If you..., St. Thomas, U. S. Virgin Islands. The fireworks will be launched from a barge stationed near the St...

FFUSION yearbook 1997. Annual report of the Finnish fusion research unit. Association EURATOM-TEKES

Energy Technology Data Exchange (ETDEWEB)

Karttunen, S; Paettikangas, T [eds.; VTT Energy, Espoo (Finland)

1998-02-01

Finnish fusion programme (FFUSION) is one of the eleven national energy research programmes funded by the Technological Development Centre of Finland (TEKES). The FFUSION programme was fully integrated into European Fusion Programme just after Finland joined the European Union. The contract of Association Euratom and Tekes was signed in 1995 and extends to the end of 1999. Finland became a member of JET Joint Undertaking in 1996, other contracts with Euratom include NET agreement and the Staff Mobility Agreement. FFUSION programme with participating research institutes and universities forms the Fusion Research Unit of the Association Euratom-Tekes. This annual report summarises the research activities of the Finnish Research Unit in 1997. The programme consists of two parts: Physics and Technology. The research areas of the physics are: Fusion plasma engineering, and Radio-frequency heating and Plasma diagnostics. The technology is focused into three areas: Fusion reactor materials (first wall components and joining techniques), Remote handling and viewing systems, and Superconductors

The National Space Biomedical Research Institute's education and public outreach program: Working toward a global 21st century space exploration society

Science.gov (United States)

MacLeish, Marlene Y.; Thomson, William A.; Moreno, Nancy P.

2011-05-01

Space Exploration educators worldwide are confronting challenges and embracing opportunities to prepare students for the global 21st century workforce. The National Space Biomedical Research Institute (NSBRI), established in 1997 through a NASA competition, is a 12-university consortium dedicated to space life science research and education. NSBRI's Education and Public Outreach Program (EPOP) is advancing the Institute's mission by responding to global educational challenges through activities that: provide teacher professional development; develop curricula that teach students to communicate with their peers across the globe; provide women and minority US populations with greater access to, and awareness of science careers; and promote international science education partnerships. A recent National Research Council (NRC) Space Studies Board Report, America's Future in Space: Aligning the Civil Program with National Needs, acknowledges that "a capable workforce for the 21st century is a key strategic objective for the US space program… (and that) US problems requiring best efforts to understand and resolve…are global in nature and must be addressed through mutual worldwide action". [1] This sentiment has gained new momentum through a recent National Aeronautics and Space Administration (NASA) report, which recommends that the life of the International Space Station be extended beyond the planned 2016 termination. [2] The two principles of globalization and ISS utility have elevated NSBRI EPOP efforts to design and disseminate science, technology, engineering and mathematics (STEM) educational materials that prepare students for full participation in a globalized, high technology society; promote and provide teacher professional development; create research opportunities for women and underserved populations; and build international educational partnerships. This paper describes select EPOP projects and makes the case for using innovative, emerging information

Aligning the National S&T Policy with the National Sustainable ...

International Development Research Centre (IDRC) Digital Library (Canada)

Investments in S&T have so far occurred on an ad-hoc basis. ... Sri Lanka, Central Asia, Far East Asia, South Asia ... research teams set to improve livestock vaccine development and production to benefit farmers across the Global South.

21ST-CENTURY TEACHERS: THE STUDENTS’ PERSPECTIVES

Directory of Open Access Journals (Sweden)

Maida Norahmi

2017-03-01

Full Text Available The issues regarding the demands of creative, innovative, and professional teachers are certainly on the concern of stakeholders and practitioners in education. Substantial efforts were conducted by the government to meet the 21st-century teachers having the four competencies required for being a teacher and coping with the needs of modern education. A survey research was conducted to collect respondents’ opinion as the main source of data to describe whether the 21st-century teachers are on the demands and to gain information that the students have a similar perception to teacher’s competencies required by the government. Seventy-five questionnaires related to the competencies were given to students of English Education Study Program of 2013 to 2016. The questionnaires were aimed at collecting written information dealing with what the students perceived towards the activities implemented by teachers in the process of teaching and learning. The result of questionnaire analysis revealed that most students expected the 21st-century teachers to have skills in teaching and in connecting it with the development of today’s technology and today’s student characteristics. The data also showed that the students constructed the same characteristics of teacher’s competencies required by the government regarding pedagogy, personality, sociality, and professionality.

Different properties of polysialic acids synthesized by the polysialyltransferases ST8SIA2 and ST8SIA4.

Science.gov (United States)

Mori, Airi; Hane, Masaya; Niimi, Yuki; Kitajima, Ken; Sato, Chihiro

2017-09-01

Polysialic acid (polySia) is mainly found as a modification of neural cell adhesion molecule (NCAM) in whole embryonic brains, as well as restricted areas of adult vertebrate brains, including the hippocampus. PolySia shows not only repulsive effects on NCAM-involved cell-cell interactions due to its bulky and hydrated properties, but also attractive effects on the interaction with neurologically active molecules, which exerts a reservoir function. Two different polysialyltransferases, ST8SIA2 and ST8SIA4, are involved in the synthesis of polySia chains; however, to date, the differences of the properties between polySia chains synthesized by these two enzymes remain unknown. In this study, to clarify this point, we first prepared polySia-NCAMs from HEK293 cells stably expressing ST8SIA4 and ST8SIA2, or ST8SIA2 (SNP-7), a mutant ST8SIA2 derived from a schizophrenia patient. The conventional sensitive chemical and immunological characterizations showed that the quantity and quality (structural features) of polySia are not so much different between ST8SIA4- and ST8SIA2-synthesized ones, apart from those of ST8SIA2 (SNP-7). Then, we assessed the homophilic and heterophilic interactions mediated by polySia-NCAM by adopting a surface plasmon resonance measurement as an in vitro analytical method. Our novel findings are as follows: (i) the ST8SIA2- and ST8SIA4-synthesized polySia-NCAMs exhibited different attractive and repulsive effects than each other; (ii) both polySia- and oligoSia-NCAMs synthesized by ST8SIA2 were able to bind polySia-NCAMs; (iii) the polySia-NCAM synthesized by a ST8SIA2 (SNP-7) showed markedly altered attractive and repulsive properties. Collectively, polySia-NCAM is suggested to simultaneously possess both attractive and repulsive properties that are highly regulated by the two polysialyltransferases. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Special issue: engineering toxins for 21st-century therapies: introduction.

Science.gov (United States)

Acharya, K Ravi

2011-12-01

This special issue on 'Engineering toxins for 21st century therapies' provides a critical review of the current state of multifaceted aspects of toxin research by some of the leading researchers in the field. It also highlights the clinical potential and challenges for development of novel biologics based on engineered toxin derived products. © 2011 The Author Journal compilation © 2011 FEBS.

A continuing success - The United States Foreign Research Reactor Spent Nuclear Fuel Acceptance Program

International Nuclear Information System (INIS)

Mustin, Tracy P.; Clapper, Maureen; Reilly, Jill E.

2000-01-01

The United States Department of Energy, in consultation with the Department of State, adopted the Nuclear Weapons Nonproliferation Policy Concerning Foreign Research Reactor Spent Nuclear Fuel in May 1996. To date, the Foreign Research Reactor (FRR) Spent Nuclear Fuel (SNF) Acceptance Program, established under this policy, has completed 16 spent fuel shipments. 2,651 material test reactor (MTR) assemblies, one Slowpoke core containing less than 1 kilogram of U.S.-origin enriched uranium, 824 Training, Research, Isotope, General Atomic (TRIGA) rods, and 267 TRIGA pins from research reactors around the world have been shipped to the United States so far under this program. As the FRR SNF Acceptance Program progresses into the fifth year of implementation, a second U.S. cross country shipment has been completed, as well as a second overland truck shipment from Canada. Both the cross country shipment and the Canadian shipment were safely and successfully completed, increasing our knowledge and experience in these types of shipments. In addition, two other shipments were completed since last year's RERTR meeting. Other program activities since the last meeting included: taking pre-emptive steps to avoid license amendment pitfalls/showstoppers for spent fuel casks, publication of a revision to the Record of Decision allowing up to 16 casks per ocean going vessel, and the issuance of a cable to 16 of the 41 eligible countries reminding their governments and the reactor operators that the U.S.-origin uranium in their research reactors may be eligible for return to the United States under the Acceptance Program and urging them to begin discussions on shipping schedules. The FRR SNF program has also supported the Department's implementation of the competitive pricing policy for uranium and resumption of shipments of fresh uranium for fabrication into assemblies for research reactors. The United States Foreign Research Reactor Spent Nuclear Fuel Acceptance Program continues

77 FR 59035 - Notice of Intent To Rule on Request To Release Airport Property at the St. George Airport, St...

Science.gov (United States)

2012-09-25

... To Release Airport Property at the St. George Airport, St. George, UT AGENCY: Federal Aviation... rule and invite public comment on the release of land at St. George Airport under the provisions of..., City of St. George, Utah, at the following address: Mr. Gary Esplin, City Manager, City of St. George...

Product- and Process Units in the CRITT Translation Process Research Database

DEFF Research Database (Denmark)

Carl, Michael

than 300 hours of text production. The database provides the raw logging data, as well as Tables of pre-processed product- and processing units. The TPR-DB includes various types of simple and composed product and process units that are intended to support the analysis and modelling of human text......The first version of the "Translation Process Research Database" (TPR DB v1.0) was released In August 2012, containing logging data of more than 400 translation and text production sessions. The current version of the TPR DB, (v1.4), contains data from more than 940 sessions, which represents more...

Complete Circular Genome Sequence of Successful ST8/SCCmecIV Community-Associated Methicillin-Resistant Staphylococcus aureus (OC8 in Russia: One-Megabase Genomic Inversion, IS256's Spread, and Evolution of Russia ST8-IV.

Directory of Open Access Journals (Sweden)

Tsai-Wen Wan

Full Text Available ST8/SCCmecIV community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA has been a common threat, with large USA300 epidemics in the United States. The global geographical structure of ST8/SCCmecIV has not yet been fully elucidated. We herein determined the complete circular genome sequence of ST8/SCCmecIVc strain OC8 from Siberian Russia. We found that 36.0% of the genome was inverted relative to USA300. Two IS256, oppositely oriented, at IS256-enriched hot spots were implicated with the one-megabase genomic inversion (MbIN and vSaβ split. The behavior of IS256 was flexible: its insertion site (att sequences on the genome and junction sequences of extrachromosomal circular DNA were all divergent, albeit with fixed sizes. A similar multi-IS256 system was detected, even in prevalent ST239 healthcare-associated MRSA in Russia, suggesting IS256's strong transmission potential and advantage in evolution. Regarding epidemiology, all ST8/SCCmecIVc strains from European, Siberian, and Far Eastern Russia, examined had MbIN, and geographical expansion accompanied divergent spa types and resistance to fluoroquinolones, chloramphenicol, and often rifampicin. Russia ST8/SCCmecIVc has been associated with life-threatening infections such as pneumonia and sepsis in both community and hospital settings. Regarding virulence, the OC8 genome carried a series of toxin and immune evasion genes, a truncated giant surface protein gene, and IS256 insertion adjacent to a pan-regulatory gene. These results suggest that unique single ST8/spa1(t008/SCCmecIVc CA-MRSA (clade, Russia ST8-IVc emerged in Russia, and this was followed by large geographical expansion, with MbIN as an epidemiological marker, and fluoroquinolone resistance, multiple virulence factors, and possibly a multi-IS256 system as selective advantages.

Complete Circular Genome Sequence of Successful ST8/SCCmecIV Community-Associated Methicillin-Resistant Staphylococcus aureus (OC8) in Russia: One-Megabase Genomic Inversion, IS256's Spread, and Evolution of Russia ST8-IV.

Science.gov (United States)

Wan, Tsai-Wen; Khokhlova, Olga E; Iwao, Yasuhisa; Higuchi, Wataru; Hung, Wei-Chun; Reva, Ivan V; Singur, Olga A; Gostev, Vladimir V; Sidorenko, Sergey V; Peryanova, Olga V; Salmina, Alla B; Reva, Galina V; Teng, Lee-Jene; Yamamoto, Tatsuo

2016-01-01

ST8/SCCmecIV community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been a common threat, with large USA300 epidemics in the United States. The global geographical structure of ST8/SCCmecIV has not yet been fully elucidated. We herein determined the complete circular genome sequence of ST8/SCCmecIVc strain OC8 from Siberian Russia. We found that 36.0% of the genome was inverted relative to USA300. Two IS256, oppositely oriented, at IS256-enriched hot spots were implicated with the one-megabase genomic inversion (MbIN) and vSaβ split. The behavior of IS256 was flexible: its insertion site (att) sequences on the genome and junction sequences of extrachromosomal circular DNA were all divergent, albeit with fixed sizes. A similar multi-IS256 system was detected, even in prevalent ST239 healthcare-associated MRSA in Russia, suggesting IS256's strong transmission potential and advantage in evolution. Regarding epidemiology, all ST8/SCCmecIVc strains from European, Siberian, and Far Eastern Russia, examined had MbIN, and geographical expansion accompanied divergent spa types and resistance to fluoroquinolones, chloramphenicol, and often rifampicin. Russia ST8/SCCmecIVc has been associated with life-threatening infections such as pneumonia and sepsis in both community and hospital settings. Regarding virulence, the OC8 genome carried a series of toxin and immune evasion genes, a truncated giant surface protein gene, and IS256 insertion adjacent to a pan-regulatory gene. These results suggest that unique single ST8/spa1(t008)/SCCmecIVc CA-MRSA (clade, Russia ST8-IVc) emerged in Russia, and this was followed by large geographical expansion, with MbIN as an epidemiological marker, and fluoroquinolone resistance, multiple virulence factors, and possibly a multi-IS256 system as selective advantages.

China's S&T Emergence: A Proposal for U.S. DOD-China Collaboration in Fundamental Research

National Research Council Canada - National Science Library

Berry, William; Loeb, Cheryl

2008-01-01

...). China has committed to an ambitious strategy to increase its investments in S&T and in a workforce capable of making it a world class center for technological innovation that will drive its future economic and national security...

The United States of America and scientific research.

Science.gov (United States)

Hather, Gregory J; Haynes, Winston; Higdon, Roger; Kolker, Natali; Stewart, Elizabeth A; Arzberger, Peter; Chain, Patrick; Field, Dawn; Franza, B Robert; Lin, Biaoyang; Meyer, Folker; Ozdemir, Vural; Smith, Charles V; van Belle, Gerald; Wooley, John; Kolker, Eugene

2010-08-16

To gauge the current commitment to scientific research in the United States of America (US), we compared federal research funding (FRF) with the US gross domestic product (GDP) and industry research spending during the past six decades. In order to address the recent globalization of scientific research, we also focused on four key indicators of research activities: research and development (R&D) funding, total science and engineering doctoral degrees, patents, and scientific publications. We compared these indicators across three major population and economic regions: the US, the European Union (EU) and the People's Republic of China (China) over the past decade. We discovered a number of interesting trends with direct relevance for science policy. The level of US FRF has varied between 0.2% and 0.6% of the GDP during the last six decades. Since the 1960s, the US FRF contribution has fallen from twice that of industrial research funding to roughly equal. Also, in the last two decades, the portion of the US government R&D spending devoted to research has increased. Although well below the US and the EU in overall funding, the current growth rate for R&D funding in China greatly exceeds that of both. Finally, the EU currently produces more science and engineering doctoral graduates and scientific publications than the US in absolute terms, but not per capita. This study's aim is to facilitate a serious discussion of key questions by the research community and federal policy makers. In particular, our results raise two questions with respect to: a) the increasing globalization of science: "What role is the US playing now, and what role will it play in the future of international science?"; and b) the ability to produce beneficial innovations for society: "How will the US continue to foster its strengths?"

The United States of America and scientific research.

Directory of Open Access Journals (Sweden)

Gregory J Hather

2010-08-01

Full Text Available To gauge the current commitment to scientific research in the United States of America (US, we compared federal research funding (FRF with the US gross domestic product (GDP and industry research spending during the past six decades. In order to address the recent globalization of scientific research, we also focused on four key indicators of research activities: research and development (R&D funding, total science and engineering doctoral degrees, patents, and scientific publications. We compared these indicators across three major population and economic regions: the US, the European Union (EU and the People's Republic of China (China over the past decade. We discovered a number of interesting trends with direct relevance for science policy. The level of US FRF has varied between 0.2% and 0.6% of the GDP during the last six decades. Since the 1960s, the US FRF contribution has fallen from twice that of industrial research funding to roughly equal. Also, in the last two decades, the portion of the US government R&D spending devoted to research has increased. Although well below the US and the EU in overall funding, the current growth rate for R&D funding in China greatly exceeds that of both. Finally, the EU currently produces more science and engineering doctoral graduates and scientific publications than the US in absolute terms, but not per capita. This study's aim is to facilitate a serious discussion of key questions by the research community and federal policy makers. In particular, our results raise two questions with respect to: a the increasing globalization of science: "What role is the US playing now, and what role will it play in the future of international science?"; and b the ability to produce beneficial innovations for society: "How will the US continue to foster its strengths?"

Nigeria and the United States: An Analysis of National Goals

National Research Council Canada - National Science Library

McCarthy, John M

2008-01-01

Since the beginning of the 21st century, the continent of Africa has regained its importance to the United States and other developed nations, primarily due to its vast amounts of untapped resources...

78 FR 16208 - Safety Zone; V. I. Carnival Finale; St. Thomas Harbor; St. Thomas, U.S. Virgin Islands

Science.gov (United States)

2013-03-14

... 1625-AA00 Safety Zone; V. I. Carnival Finale; St. Thomas Harbor; St. Thomas, U.S. Virgin Islands AGENCY... establish a safety zone on the waters of St. Thomas Harbor in St. Thomas, U. S. Virgin Islands during the V... between 9 a.m. and 5 p.m., Monday through Friday, except federal holidays. The telephone number is 202-366...

Developing 21st Century Process Skills through Project Design

Science.gov (United States)

Yoo, Jeong-Ju; MacDonald, Nora M.

2014-01-01

The goal of this paper is to illustrate how the promotion of 21st Century process skills can be used to enhance student learning and workplace skill development: thinking, problem solving, collaboration, communication, leadership, and management. As an illustrative case, fashion merchandising and design students conducted research for a…

Monitoring birds, reptiles and butterflies in the St Katherine ...

African Journals Online (AJOL)

INTRODUCTION. Egypt has a ... mixed blessing of tourism, which increases the value of preserving the region's wildlife, but .... Canal University's Research Centre at the edge of the town of St Katherine for approximately .... distance from the observer, the whole basis of the Line Transect method. ...... Concise edition. Oxford ...

Diagnosis of Fatal Human Case of St. Louis Encephalitis Virus Infection by Metagenomic Sequencing, California, 2016.

Science.gov (United States)

Chiu, Charles Y; Coffey, Lark L; Murkey, Jamie; Symmes, Kelly; Sample, Hannah A; Wilson, Michael R; Naccache, Samia N; Arevalo, Shaun; Somasekar, Sneha; Federman, Scot; Stryke, Doug; Vespa, Paul; Schiller, Gary; Messenger, Sharon; Humphries, Romney; Miller, Steve; Klausner, Jeffrey D

2017-10-01

We used unbiased metagenomic next-generation sequencing to diagnose a fatal case of meningoencephalitis caused by St. Louis encephalitis virus in a patient from California in September 2016. This case is associated with the recent 2015-2016 reemergence of this virus in the southwestern United States.

St. Lucia.

Science.gov (United States)

1987-06-01

The population of St Lucia was 123,000 in 1986, with an annual growth rate of 2%. The infant mortality rate stands at 22.2/1000 live births, and life expectancy is 70.3 years for males and 74.9 years for females. The literacy rate is 78%. St Lucia's labor force is allocated as follows: agriculture, 36.6%; industry and commerce, 20.1%; and services, 18.1%. The gross national product (GNP) was US$146 million in 1985, with an annual growth rate of 3% and a per capita GNP of $1071. St Lucia is a parliamentary democracy modeled on the British Westminster system. The island is divided into 16 parishes and 1 urban area (the capital, Castries). St Lucia is currently a politically stable country, although the high level of youth unemployment is a cause for concern. Ongoing stability may depend on the government's ability to provide services such as jobs and housing. The economy has evolved from a monocrop sugar plantation type to a diversified economy based on agriculture, industry, and tourism. Agriculture, dominated by the banana industry, is characterized by the participation of a large number of small and medium-sized enterprises. Industry is being encouraged through the provision of incentives such as tax rebates. The government is attempting to maintain a sound investment climate through a tripartite dialogue with the private sector and trade unions. Overall economic policy is predicated on the attraction of sound investments, by both local and foreign entities, to accelerate the rate of economic growth, solve the unemployment problem, and generate a solid balance-of-payments position.

Forum: House of Cards--or--Trojan Horse?: A Response to Ralf St. Clair's House of Cards: Analyzing "Making Skills Everyone's Business"

Science.gov (United States)

Scully-Russ, Ellen

2015-01-01

In this article, Ellen Scully-Russ responds to St. Clair's analysis (EJ1072357) of the recent policy report from the Office of Career, Technical and Adult Education, "Making Skills Everyone's Business: A Call to Transform Adult Learning in the United States" (MSEB) (United States Department of Education [USDoE], 2015). While Scully-Russ…

Using "The Joy Luck Club" to Teach Core Standards and 21st Century Literacies

Science.gov (United States)

Burns, Leslie David; Botzakis, Stergios G.

2012-01-01

In this article the authors illustrate an instructional unit based on a Common Core grades 9-10 illustrative text--Amy Tan's "Two Kinds" from "The Joy Luck Club." They demonstrate how teachers can meet the new standards "and" respond to students' 21st-century needs by using this modern classic along with other traditional and new media resources.…

Development of HANARO ST3 shield

International Nuclear Information System (INIS)

Park, K. N.; Lee, J. S.; Shim, H. S.

2004-12-01

This report contains the design, fabrication and accurate installation of ST3 shield, which would be installed at ST3 beam port of HANARO. At first, we designed and fabricated ST3 shield casemate composed of 14 blocks. We filled it with heavy concrete, lead ingot and polyethylene that mixed B 4 C powder and epoxy. The average filling density of total shield casemate was 4.7g/cm 3 . The developed ST3 shield was installed at the ST3 beam port and the accuracy of installation for each beam path and channel was evaluated. We found that the extraction of neutron beam to meet the requirement of neutron spectrometer is possible. Also, we developed ancillary equipment such as BGU, quick shutter and exterior shield door for the effective opening and closing of neutron beam. As a result of this study, it was found that neutron spectrometer such as neutron reflectometer and high intensity powder diffractomater can be installed at the ST3 beam port

Proceeding of 29th domestic symposium on computational science and nuclear energy in the 21st century

International Nuclear Information System (INIS)

2001-10-01

As the 29th domestic symposium of Atomic Energy Research Committee, the Japan Welding Engineering Society, the symposium was held titled as Computational science and nuclear energy in the 21st century'. Keynote speech was delivered titled as 'Nuclear power plants safety secured by computational science in the 21st century'. Three speakers gave lectures titled as 'Materials design and computational science', 'Development of advanced reactor in the 21st century' and 'Application of computational science to operation and maintenance management of plants'. Lectures held panel discussion titled as 'Computational science and nuclear energy in the 21st century'. (T. Tanaka)

Forces for Failure and Genocide: The Plantation Model of Urban Educational Policy Making in St. Louis

Science.gov (United States)

Jones, Bruce Anthony

2005-01-01

This article is about policy decision making and racial politics in the St. Louis, Missouri, school district. From a research standpoint, traditional policymaking models are inadequate for explaining the evolution of school reform events in St. Louis over the past year. Teachers, principals, school staff, and parents perceive themselves to be…

1st IAEA research coordination meeting on tritium retention in fusion reactor plasma facing components. October 5-6, 1995, Vienna, Austria. Summary report

International Nuclear Information System (INIS)

Langley, R.A.

1995-12-01

The proceedings and results of the 1st IAEA research Coordination Meeting on ''Tritium Retention in Fusion Reactor Plasma Facing Components'' held on October 5 and 6, 1995 at the IAEA Headquarters in Vienna are briefly described. This report includes a summary of presentations made by the meeting participants, the results of a data survey and needs assessment for the retention, release and removal of tritium from plasma facing components, a summary of data evaluation, and recommendations regarding future work. (author). 4 tabs

Complete Circular Genome Sequence of Successful ST8/SCCmecIV Community-Associated Methicillin-Resistant Staphylococcus aureus (OC8) in Russia: One-Megabase Genomic Inversion, IS256’s Spread, and Evolution of Russia ST8-IV

Science.gov (United States)

Wan, Tsai-Wen; Higuchi, Wataru; Hung, Wei-Chun; Reva, Ivan V.; Singur, Olga A.; Gostev, Vladimir V.; Sidorenko, Sergey V.; Peryanova, Olga V.; Salmina, Alla B.; Reva, Galina V.; Teng, Lee-Jene; Yamamoto, Tatsuo

2016-01-01

ST8/SCCmecIV community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been a common threat, with large USA300 epidemics in the United States. The global geographical structure of ST8/SCCmecIV has not yet been fully elucidated. We herein determined the complete circular genome sequence of ST8/SCCmecIVc strain OC8 from Siberian Russia. We found that 36.0% of the genome was inverted relative to USA300. Two IS256, oppositely oriented, at IS256-enriched hot spots were implicated with the one-megabase genomic inversion (MbIN) and vSaβ split. The behavior of IS256 was flexible: its insertion site (att) sequences on the genome and junction sequences of extrachromosomal circular DNA were all divergent, albeit with fixed sizes. A similar multi-IS256 system was detected, even in prevalent ST239 healthcare-associated MRSA in Russia, suggesting IS256’s strong transmission potential and advantage in evolution. Regarding epidemiology, all ST8/SCCmecIVc strains from European, Siberian, and Far Eastern Russia, examined had MbIN, and geographical expansion accompanied divergent spa types and resistance to fluoroquinolones, chloramphenicol, and often rifampicin. Russia ST8/SCCmecIVc has been associated with life-threatening infections such as pneumonia and sepsis in both community and hospital settings. Regarding virulence, the OC8 genome carried a series of toxin and immune evasion genes, a truncated giant surface protein gene, and IS256 insertion adjacent to a pan-regulatory gene. These results suggest that unique single ST8/spa1(t008)/SCCmecIVc CA-MRSA (clade, Russia ST8-IVc) emerged in Russia, and this was followed by large geographical expansion, with MbIN as an epidemiological marker, and fluoroquinolone resistance, multiple virulence factors, and possibly a multi-IS256 system as selective advantages. PMID:27741255

Drinking games and contextual factors of 21st birthday drinking.

Science.gov (United States)

Neighbors, Clayton; Rodriguez, Lindsey M; Rinker, Dipali V; DiBello, Angelo M; Young, Chelsie M; Chen, Chun-Han

2014-09-01

21st birthday celebrations are among the highest risks for alcohol use throughout emerging adulthood and celebrants often experience a range of alcohol-related consequences. The present research considered what happens when drinking games are paired with an already high-risk event (i.e., 21st birthday celebrations) and how drinking games compare with other contextual factors on 21st birthdays. Approximately four days after turning 21, 1124 college students (55% women) completed an online survey assessing alcohol use and related consequences experienced during their birthday celebrations. Participants were also asked whether drinking games and other contextual factors were associated with their celebrations. Overall, 18% of participants reported playing drinking games during their 21st birthday celebrations. These individuals reported consuming more alcohol, had higher estimated BACs, and experienced more negative consequences than those who did not play drinking games. The association between playing drinking games and alcohol use and negative consequences was stronger for men. The effect of drinking games on negative consequences was mediated through elevated BAC levels. Receiving bar specials, having drinks purchased, playing drinking games, and loud music were uniquely and significantly associated with all alcohol outcomes. Together, these results suggest that drinking games are part of a larger context of risk contributing to extreme drinking on 21st birthdays. Furthermore, these results will help to facilitate interventions that are more individually tailored to target specific contextual risks, behaviors, and events.

2015 USAFA Research Report: Discover Falcon Innovation

Science.gov (United States)

2015-01-01

geotechnical, structures, environmental and construction. First, in the geotechnical division, Lt Col Chris Senseney is researching “Computational Modeling of...communicate. “It’s a new area for us,” said Lt Col Chris McClernon, director of the center. “We started it last summer, because we know communications...Sales de Souza, Major Mark Braun, 1st Lt Melanie Ortiz, 1st Lt Seth Rodgers and Cadet 1st Class Jordan Higgins are working on a research project

Research on Key Technologies of Unit-Based CNC Machine Tool Assembly Design

Directory of Open Access Journals (Sweden)

Zhongqi Sheng

2014-01-01

Full Text Available Assembly is the part that produces the maximum workload and consumed time during product design and manufacturing process. CNC machine tool is the key basic equipment in manufacturing industry and research on assembly design technologies of CNC machine tool has theoretical significance and practical value. This study established a simplified ASRG for CNC machine tool. The connection between parts, semantic information of transmission, and geometric constraint information were quantified to assembly connection strength to depict the assembling difficulty level. The transmissibility based on trust relationship was applied on the assembly connection strength. Assembly unit partition based on assembly connection strength was conducted, and interferential assembly units were identified and revised. The assembly sequence planning and optimization of parts in each assembly unit and between assembly units was conducted using genetic algorithm. With certain type of high speed CNC turning center, as an example, this paper explored into the assembly modeling, assembly unit partition, and assembly sequence planning and optimization and realized the optimized assembly sequence of headstock of CNC machine tool.

Hydrologic Forecasting in the 21st Century: Challenges and Directions of Research

Science.gov (United States)

Restrepo, P.; Schaake, J.

2009-04-01

Traditionally, the role of the Hydrology program of the National Weather Service has been centered around forecasting floods, in order to minimize loss of lives and damage to property as a result of floods as well as water levels for navigable rivers, and water supply in some areas of the country. A number of factors, including shifting population patterns, widespread drought and concerns about climate change have made it imperative to widen the focus to cover forecasting flows ranging from drought to floods and anything in between. Because of these concerns, it is imperative to develop models that rely more on the physical characteristics of the watershed for parameterization and less on historical observations. Furthermore, it is also critical to consider explicitly the sources of uncertainty in the forecasting process, including parameter values, model structure, forcings (both observations and forecasts), initial conditions, and streamflow observations. A consequence of more widespread occurrence of low flows as a result either of the already evident earlier snowmelt in the Western United States, or of the predicted changes in precipitation patterns, is the issue of water quality: lower flows will have higher concentrations of certain pollutants. This paper describes the current projects and future directions of research for hydrologic forecasting in the United States. Ongoing projects on quantitative precipitation and temperature estimates and forecasts, uncertainty modeling by the use of ensembles, data assimilation, verification, distributed conceptual modeling will be reviewed. Broad goals of the research directions are: 1) reliable modeling of the different sources of uncertainty. 2) a more expeditious and cost-effective approach by reducing the effort required in model calibration; 3) improvements in forecast lead-time and accuracy; 4) an approach for rapid adjustment of model parameters to account for changes in the watershed, both rapid as the result

Commercial operation and outage experience of ABWR at Kashiwazaki-Kariwa units Nos. 6 and 7

International Nuclear Information System (INIS)

Anahara, N.; Yamada, M.; Kataoka, H.

2000-01-01

Kashiwazaki-Kariwa Nuclear Power Station Units Nos. 6 and 7, the world's first ABWRs (Advanced Boiling Water Reactor), started commercial operation on November 7, 1996 and July 2, 1997, respectively, and continued their commercial operation with a high capacity factor, low occupational radiation exposure and radioactive waste. Units 6 and 7 were in their 3rd cycle operation until 25th April 1999 and 1st November 1999, respectively. Thermal efficiency was 35.4-35.8% (design thermal efficiency: 34.5%) during these period, demonstrating better performance than that of BWR-5 (design thermal efficiency: 33.4%). Nos. 6 and 7 have experienced 2 annual outages. The first outage of unit No. 6 started on November 20, 1997 and was completed within 61 days (including 6 New Year holidays), and the second outage started on March 13, 1999 and was completed within 44 days. The first annual outage of unit No. 7 started on May 27, 1998, earlier than it would normally have been, to avoid an annual outage during the summer, and was completed within 55 days, and the second outage started on September 18th, 1999 and was completed within 45 days, All annual outages were carried out within a very short time period without any severe malfunctions, including newly designed ABWR systems and equipment. As the first outage in Japan, 55 days is a very short period, despite the fact that the Nos. 6 and 7 are the first ABWRs in the world and the largest capacity units in Japan. The total occupational radiation exposure of No. 6 was 300 man-mSv (1st outage) and 331 man-mSv (2nd outage). That of Unit 7 was 153 man-mSv (1st outage) Those of unit No. 6 were at the same level as those of unit No. 3, which is the latest design 1100MW(e) BWR-5. That of unit No. 7 was the lowest ever at Kashiwazaki-Kariwa nuclear power station. The drums of radioactive waste discharged during the annual outage numbered 54 (1st outage) for No. 6 and 62 (1st outage) for No. 7, which was less than the design target of 100

Moscow and St. Petersburgpsychological schools: from opposition to friendship

Directory of Open Access Journals (Sweden)

Victor M. Allakhverdov

2016-09-01

Full Text Available The paper is an attempt to summarize the interaction of the two largest schools of psychology in Russia: the psychological schools of Moscow and St. Petersburg. The paper is a sketch dedicated to the 50th anniversary of the psychological faculties of Moscow and St. Petersburg, and should not be appreciated as a historical treatise. Tense ties between the psychological schools, that originate in the distant past, have gone through different historical stages. Slavophilevs Westernizer traditions affected the initial difference in these schoolsemerging into the opposition: either the human being is studied entirety with his/her vast subjective experience, but losing the reliability of our statements (peculiarity of Moscow school, or we study the human being accurately using objective methods, but losing the integrity of our ideas (peculiarity of St.-Petersburg school. Both psychological schools, having gone through the ups and downs, have retained their identity and their emphasis on research. Moscow scholars in their studies are aimed to larger issues and still rely on large-scale Vygotsky-Leontiev approach. Scholars of St.-Petersburgtouch upon more specific issues using empirical methods, but still continue with nostalgia and hope making plans about creating a common concept of human individual according to Ananiev. Nowadays between the two schools there is no opposition, but only one mutual love.

Developmental process and early phases of implementation for the United States Interagency Committee on Human Nutrition Research National Nutrition Research Roadmap

Science.gov (United States)

The United States Congress first called for improved coordination of human nutrition research within and among federal departments and agencies in the 1977 Farm Bill. Today, the Interagency Committee on Human Nutrition Research (ICHNR) is charged with improving the planning, coordination, and commu...

Observer variability and optimal criteria of transient ischemia during ST monitoring with continuous 12-lead ECG.

Science.gov (United States)

Jernberg, Tomas; Cronblad, Jörgen; Lindahl, Bertil; Wallentin, Lars

2002-07-01

ST monitoring with continuous 12-lead ECG is a well-established method in patients with unstable coronary artery disease (CAD). However, the method lacks documentation on optimal criteria for episodes of transient ischemia and on observer variability. Observer variability was evaluated in 24-hour recordings from 100 patients with unstable CAD with monitoring in the coronary care unit. Influence on ST changes by variations in body position were evaluated by monitoring 50 patients in different body positions. Different criteria of transient ischemia and their predictive importance were evaluated in 630 patients with unstable CAD who underwent 12 hours of monitoring and thereafter were followed for 1 to13 months. Two sets of criteria were tested: (1) ST deviation > or = 0.1 mV for at least 1 minute, and (2) ST depression > or = 0.05 mV or elevation > or = 0.1 mV for at least 1 minute. When the first set of criteria were used, the interobserver agreement was good (kappa = 0.72) and 8 (16%) had significant ST changes in at least one body position. Out of 100 patients with symptoms suggestive of unstable CAD and such ischemia, 24 (24%) had a cardiac event during follow-up. When the second set of criteria were used, the interobserver agreement was poor (kappa = 0.32) and 21 (42%) had significant ST changes in at least one body position. Patients fulfilling the second but not the first set of criteria did not have a higher risk of cardiac event than those without transient ischemia (5.3 vs 4.3%). During 12-lead ECG monitoring, transient ischemic episodes should be defined as ST deviations > or = 0.1 mV for at least 1 minute, based on a low observer variability, minor problems with postural ST changes and an important predictive value.

Five Forces of 21st Century Innovation Strategy: Insights for Leaders

Energy Technology Data Exchange (ETDEWEB)

Arent, Douglas J.; Pless, Jacquelyn; Statwick, Patricia

2016-03-01

Understanding these dynamics informs 21st century innovation strategies that government and business leaders rely upon to address modern technological, social, environmental, and demographic realities. This Research Highlight previews JISEA's continuing work on innovation strategy.

District heating/cogeneration application studies for the Minneapolis-St Paul area. Executive summary; overall feasibility and economic viability for a district heating/new cogeneration system in Minneapolis-St. Paul

Energy Technology Data Exchange (ETDEWEB)

Margen, P.; Larsson, K.; Cronholm, L.A.; Marklund, J.E.

1979-08-01

A study was undertaken to determine the feasibility of introducing a large-scale, hot-water, district-heating system for the Minneapolis-St. Paul area. The analysis was based on modern European hot-water district-heating concepts in which cogeneration power plants supply the base-load thermal energy. Heat would be supplied from converted turbines of existing coal-fired power plants in Minneapolis and St. Paul. Toward the end of the 20-year development period, one or two new cogeneration units would be required. Thus, the district-heating system could use low-grade heat from either coal-fired or nuclear cogeneration power stations to replace the space-heating fuels currently used - natural gas and distillate oil. The following conclusions can be drawn: the concept is technically feasible, it has great value for fuel conservation, and with appropriate financing the system is economically viable.

Výzkum sportovního vyžití mládeže v Ústí nad Orlicí

OpenAIRE

Johanidesová, Šárka

2012-01-01

Title: Youth sports activities research in Ústí nad Orlicí Objecvive: The aim of study is to measure of usage of sports facilities by youth in Ústí nad Orlicí and their satisfaction with them. Subsequent interpretations of youth interests in sports. Methods: At theoretical part synthesis method will be used. The research itself will be based on quantitative method - interviewing. Respondents will be students of second grade of elementary schools and high schools in Ústí nad Orlicí. Results: A...

Quench tank in-leakage diagnosis at St. Lucie

Energy Technology Data Exchange (ETDEWEB)

Price, J.E.; Au-Yang, M.K.; Beckner, D.A.; Vickery, A.N.

1996-12-01

In February 1995, leakage into the quench tank of the St. Lucie Nuclear Station Unit 1 was becoming an operational concern. This internal leak resulted in measurable increases in both the temperature and level of the quench tank water, and was so severe that, if the trend continued, plant shut down would be necessary. Preliminary diagnosis based on in-plant instrumentation indicated that any one of 11 valves might be leaking into the quench tank. This paper describes the joint effort by two teams of engineers--one from Florida Power & Light, the other from Framatome Technologies--to identify the sources of the leak, using the latest technology developed for valve diagnosis.

Teknisk Ståbi

DEFF Research Database (Denmark)

Teknisk Ståbi er de bygningsprojekterendes og entreprenørers håndbog. Den dækker matematik, fysik, statestik, laster og sikkerhed samt beggematerialerne: beton, stål, træ, murværk, letbeton, glas og endelig fundering. Denne udgave er en næsten totalrevision, baseret på de nye Eurocodes, der afløs...

[Ethics of research in psychiatry. Comparison of France and the United States].

Science.gov (United States)

Lemoine, P; Pacault-Legendre, V

1983-01-01

This article presents a comparison of research ethics in psychopharmacology in France and the United States. The authors present some elements of definition, etymology and of history. In addition, they study how this very specific research is actually done. Many questions are discussed, including the right of the patient, and the problem of normal volunteers. Other aspects are more technical i.e. remuneration, protocol, and the product. Finally the role of the ethics committees is investigated. These committees comprise the third component of the trial that consists of the research and the subject.

A high arctic experience of uniting research and monitoring

Science.gov (United States)

Schmidt, Niels Martin; Christensen, Torben R.; Roslin, Tomas

2017-07-01

Monitoring is science keeping our thumb on the pulse of the environment to detect any changes of concern for societies. Basic science is the question-driven search for fundamental processes and mechanisms. Given the firm root of monitoring in human interests and needs, basic sciences have often been regarded as scientifically "purer"—particularly within university-based research communities. We argue that the dichotomy between "research" and "monitoring" is an artificial one, and that this artificial split clouds the definition of scientific goals and leads to suboptimal use of resources. We claim that the synergy between the two scientific approaches is well distilled by science conducted under extreme logistic constraints, when scientists are forced to take full advantage of both the data and the infrastructure available. In evidence of this view, we present our experiences from two decades of uniting research and monitoring at the remote research facility Zackenberg in High Arctic Greenland. For this site, we show how the combination of insights from monitoring with the mechanistic understanding obtained from basic research has yielded the most complete understanding of the system—to the benefit of all, and as an example to follow. We therefore urge scientists from across the continuum from monitoring to research to come together, to disregard old division lines, and to work together to expose a comprehensive picture of ecosystem change and its consequences.

21st Century jobs initiative - building the foundations for a 21st Century economy. Final main report

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-11-01

The 21st Century Jobs Initiative has been launched in the context of new realities in Washington, D.C., rapid restructuring of the US economy and accelerating changes in the makeup of the East Tennessee economy driven by these and other external economic forces. Continuing downward pressure on Federal budgets for programs that support three key institutions in the region - DOE`s Oak Ridge complex, the Tennessee Valley Authority and research programs of the University of Tennessee - are especially threatening to the region. With a large part of its economy dependent on Federal spending, the area is at risk of troublesome impacts that could ripple out from the Oak Ridge and Knoxville home of these institutions throughout the entire 15-county {open_quotes}Resource Valley.{close_quotes} As these economic forces play out in the region`s economy, important questions arise. How will East Tennessee {open_quotes}earn its living{close_quotes} in the future if the Federal government role in the economy shrinks? What kind of new industries will be formed to replace those at risk due to Federal cutbacks and economic restructuring? Where will the jobs come from for the next generation of job seekers? These are among the questions driving the 21st Century Jobs Initiative, an action-oriented program designed and implemented by local leaders in response to the economic challenges facing East Tennessee. Fortunately, the region`s economy is strong today. Unemployment is at near record lows in most counties. Moreover, leaders are increasingly aware of the threats on the horizon and are already moving to action. And the impacts from the forces at work on the economy will probably come slowly, over the next decade or so. Based on economic research and input from local leaders knowledgeable about the economy, the 21st Century Jobs Initiative has set forth a strategic economic development plan for the region.

The marine Algal Vegetation of St. Martin, St. Eustatius and Saba (Netherlands Antilles)

NARCIS (Netherlands)

Vroman, M.

1968-01-01

Along the coast of St. Martin, St. Eustatius and Saba the rocks above sea-level often show a number of differently coloured zones. This is clearly visible when the coast over a larger distance is formed by one type of rock, as for instance on Saba. In many places a light-coloured belt is seen above

FY 2001 Blue Book: Information Technology: The 21st Century Revolution

Data.gov (United States)

Networking and Information Technology Research and Development, Executive Office of the President — At the dawn of the 21st century, the U.S. is enjoying an era of unprecedented possibilities and prosperity built on dramatic advances in science and technology....

PREFACE: 1st International Conference on Rheology and Modeling of Materials

Science.gov (United States)

Gömze, László A.

2015-04-01

Understanding the rheological properties of materials and their rheological behaviors during their manufacturing processes and in their applications in many cases can help to increase the efficiency and competitiveness not only of the finished goods and products but the organizations and societies also. The more scientific supported and prepared organizations develop more competitive products with better thermal, mechanical, physical, chemical and biological properties and the leading companies apply more competitive knowledge, materials, equipment and technology processes. The idea to organize in Hungary the 1st International Conference on Rheology and Modeling of Materials we have received from prospective scientists, physicists, chemists, mathematicians and engineers from Asia, Europe, North and South America including India, Korea, Russia, Turkey, Estonia, France, Italy, United Kingdom, Chile, Mexico and USA. The goals of ic-rmm1 the 1st International Conference on Rheology and Modeling of Materials are the following: • Promote new methods and results of scientific research in the fields of modeling and measurements of rheological properties and behavior of materials under processing and applications. • Change information between the theoretical and applied sciences as well as technical and technological implantations. • Promote the communication between the scientists of different disciplines, nations, countries and continents. The international conference ic-rmm1 provides a platform among the leading international scientists, researchers, PhD students and engineers for discussing recent achievements in measurement, modeling and application of rheology in materials technology and materials science of liquids, melts, solids, crystals and amorphous structures. Among the major fields of interest are the influences of material structures, mechanical stresses temperature and deformation speeds on rheological and physical properties, phase transformation of

Basic Pay In The United States All-Volunteer Armed Forces

National Research Council Canada - National Science Library

Carson, Kenneth

2000-01-01

As the United States enters the 21st century, the readiness of its over 1.4 million all-volunteer armed forces is as important today as anytime during the 27 year history of the modern all-volunteer force (AVF...

Comparative genomics and drug resistance of a geographic variant of ST239 methicillin-resistant Staphylococcus aureus emerged in Russia.

Directory of Open Access Journals (Sweden)

Tatsuo Yamamoto

Full Text Available Two distinct classes of methicillin-resistant Staphylococcus aureus (MRSA are spreading in hospitals (as hospital-acquired MRSA, HA-MRSA and in the community (as community-acquired MRSA, CA-MRSA. Multilocus sequence type (ST 239 MRSA, one of the most worldwide-disseminated lineages, has been noted as a representative HA-MRSA. Here, we isolated ST239 MRSA (spa type 3 [t037] and staphylococcal cassette chromosome mec [SCCmec] type III.1.1.1 and its novel variant with ST239/spa351 (t030/SCCmecIII.1.1.4 (SCCmecIII(R not only from hospitals but also from patients with urethritis in the community in Russia. The Russian variant (strain 16K possessed a hybrid genome consisting of CC8 and CC30, similar to the ST239/spa3/SCCmecIII.1.1.1 HA-MRSA (TW20 genome, but with marked diversity. The 16K' CC30 section had SCCmecIII(R carrying the dcs-carrying unit (which corresponded to the SCCmecIVc J3 joining region of ST30 CA-MRSA, lacked SCCmercury, and possessed a novel mobile element structure (MES16K carrying the ccrC-carrying unit (with the recombinase gene ccrC1 allele 3 and drug resistance tranposons. The Russian variant included strains with a high ability to transfer its multiple drug resistance by conjugation; e.g., for strain 16K, the transfer frequency of a chloramphenicol resistance plasmid (p16K-1 with 2.9 kb in size reached 1.4×10(-2, followed by Tn554 conjugative transfer at 3.6×l0(-4. The Russian variant, which has been increasing recently, included divergent strains with different plasmid patterns and pulsed field gel electrophoresis profiles. The data demonstrate the alternative nature of ST239 MRSA as CA-MRSA and also as a drug resistance disseminator, and its micro but dynamic evolution in Russia.

Training Librarians for 21st Century Repository Services: Emerging Trends

Directory of Open Access Journals (Sweden)

Helen Emasealu

2016-05-01

Full Text Available The paper reviewed the emerging roles of the 21st century librarians, charged with the responsibility to manage repository services across libraries in present-day information technology environment. Librarians need to be trained and empowered with requisite skills and knowledge needed for successful management of the ICT driven repository initiatives that the 21st century demands. Literature was reviewed on the roles and responsibilities of librarians, training needs and opportunities, career path and recruitment of librarians, and community support necessary for effective and efficient implementation and management of repository initiatives. This entails the ability to comprehend trends and change patterns which are essential for providing research focused and user-friendly models in open repository services that are based on thorough analytical understanding of the challenges of emerging trends. To achieve this requires the training and retraining of librarians to reposition them as information specialists in their career path. The role of the library as an integral part of its social environment is to educate the community about the existence of an open repository by building partnership with community-oriented research centres through seminars, workshops, symposium, training, and awareness programmes. The study recommends that librarians should strategize and collaborate with researchers to make open repository an essential research tool.

NASA-UVA Light Aerospace Alloy and Structures Technology Program (LA2ST)

Science.gov (United States)

Gangloff, Richard P.; Starke, Edgar A., Jr.; Kelly, Robert G.; Scully, John R.; Shiflet, Gary J.; Stoner, Glenn E.; Wert, John A.

1997-01-01

The NASA-UVA Light Aerospace Alloy and Structures Technology (LA2ST) Program was initiated in 1986 and continues with a high level of activity. Here, we report on progress achieved between July I and December 31, 1996. The objective of the LA2ST Program is to conduct interdisciplinary graduate student research on the performance of next generation, light-weight aerospace alloys, composites and thermal gradient structures in collaboration with NASA-Langley researchers. Specific technical objectives are presented for each research project. We generally aim to produce relevant data and basic understanding of material mechanical response, environmental/corrosion behavior, and microstructure; new monolithic and composite alloys; advanced processing methods; new solid and fluid mechanics analyses; measurement and modeling advances; and a pool of educated graduate students for aerospace technologies. The accomplishments presented in this report are summarized as follows. Three research areas are being actively investigated, including: (1) Mechanical and Environmental Degradation Mechanisms in Advanced Light Metals, (2) Aerospace Materials Science, and (3) Mechanics of Materials for Light Aerospace Structures.

NASA-UVA Light Aerospace Alloy and Structures Technology Program: LA(2)ST

Science.gov (United States)

Gangloff, Richard P.; Haviland, John K.; Herakovich, Carl T.; Pilkey, Walter D.; Pindera, Marek-Jerzy; Scully, John R.; Stoner, Glenn E.; Thornton, Earl A.; Wawner, Franklin E., Jr.; Wert, John A.

1993-01-01

The NASA-UVA Light Aerospace Alloy and Structures Technology (LA(2)ST) Program continues a high level of activity, with projects being conducted by graduate students and faculty advisors in the Departments of Materials Science and Engineering, Civil Engineering and Applied Mechanics, and Mechanical and Aerospace Engineering at the University of Virginia. This work is funded by the NASA-Langley Research Center under Grant NAG-1-745. We report on progress achieved between July 1 and December 31, 1992. The objective of the LA(2)ST Program is to conduct interdisciplinary graduate student research on the performance of next generation, light weight aerospace alloys, composites and thermal gradient structures in collaboration with NASA-Langley researchers. Specific technical objectives are presented for each research project. We generally aim to produce relevant data and basic understanding of material mechanical response, corrosion behavior, and microstructure; new monolithic and composite alloys; advanced processing methods; new solid and fluid mechanics analyses; measurement advances; and critically, a pool of educated graduate students for aerospace technologies.

1st Latin American Congress on Automation and Robotics

CERN Document Server

Baca, José; Moreno, Héctor; Carrera, Isela; Cardona, Manuel

2017-01-01

This book contains the proceedings of the 1st Latin American Congress on Automation and Robotics held at Panama City, Panama in February 2017. It gathers research work from researchers, scientists, and engineers from academia and private industry, and presents current and exciting research applications and future challenges in Latin American. The scope of this book covers a wide range of themes associated with advances in automation and robotics research encountered in engineering and scientific research and practice. These topics are related to control algorithms, systems automation, perception, mobile robotics, computer vision, educational robotics, robotics modeling and simulation, and robotics and mechanism design. LACAR 2017 has been sponsored by SENACYT (Secretaria Nacional de Ciencia, Tecnologia e Inovacion of Panama).

75 FR 38723 - Safety Zone; St. Ignace 4th of July Fireworks, East Moran Bay, Lake Huron, St. Ignace, MI

Science.gov (United States)

2010-07-06

...-AA00 Safety Zone; St. Ignace 4th of July Fireworks, East Moran Bay, Lake Huron, St. Ignace, MI AGENCY... safety zone on East Moran Bay, Lake Huron, St. Ignace, Michigan. This zone is intended to restrict vessels from a portion of East Moran Bay during the St. Ignace 4th of July Fireworks display, July 4, 2010...

The basics of spherical tokamaks and progress in European research

International Nuclear Information System (INIS)

Gusev, V K; Alladio, F; Morris, A W

2003-01-01

When the aspect ratio of a tokamak (A = R/a) decreases significantly, there is a transformation of the well studied tokamak toroidal magnetic configuration into the spherical tokamak (ST) configuration. This configuration has high natural plasma elongation and triangularity and other unique equilibrium and stability properties of ST configuration, which are discussed in this paper. European research into ST physics is well advanced in spite of the young age of this branch of fusion science. An overview of selected experimental and theoretical results obtained at Ioffe, Culham and Frascati is given with the emphasis on their complementarity and links to the main stream of tokamak research, such as ITER. An outline of the basic ST advantages and the potential of ST research for new insights into magnetic confinement is also given. More detailed descriptions of recent advances in ST theory and experiment may be found in the invited papers by Akers and Ono in the proceedings of this conference

Developing 21st century skills in chemistry classrooms: Opportunities and challenges of STEAM integration

Science.gov (United States)

Hadinugrahaningsih, Tritiyatma; Rahmawati, Yuli; Ridwan, Achmad

2017-08-01

The paper portrays the first year of two-year study in integration Science, Technology, Engineering, Art, and Mathematics (STEAM) in chemistry learning. The research focused on developing 21st-century skills of chemistry students in secondary schools. The 21st-century skills as a set of abilities that students need to develop in facing the future challenge which involves learning, literacy, and life skills. The study was conducted in two secondary schools both public and private school in topics of hydrocarbon, petroleum, solubility, and acid base in year 10 and 11. The qualitative methodology was applied to explore the students' learning experiences and understanding the research context. Data was collected through observation, interview, reflective journal, and 21st-century rubric. The STEAM approach was integrated through modification of project-based learning model. The students had opportunities to develop their own projects by integrating chemistry and STEAM principles to their project. The results show that students have developed their critical and creative thinking, problem-solving skills, collaboration and argumentation skills, leadership and responsibility, information and literacy skills. The researchers faced the challenges of integrating STEAM within the chemistry curricula, empowering students, and managing the teaching and time resources. Students have started to challenge their critical and creative thinking within the existing learning environments. Integrating STEAM into chemistry learning has developed students' 21st-century skills in those three areas. Teachers also learned to develop their competencies for being facilitators and agents of change, in addition to skills development in dealing with students' differences.

REPERFUSION THERAPY IN ACUTE CORONARY SYNDROME WITH ST SEGMENT ELEVATION

Directory of Open Access Journals (Sweden)

A. L. Alyavi

2016-01-01

Full Text Available Aim. To compare effect of percutaneous balloon angioplasty (PCA and a systemic thrombolysis (STL on the central and intracardiac hemodynamics in patients with acute coronary syndrome (ACS with ST segment elevation.Material and methods. 80 patients with ACS with ST segment elevation were included in the study. Patients were split into 2 groups depending on reperfusion strategy. PCA was performed in 55 patients (first group. 25 patients of the second group had STL with Streptokinase, i/v, 1 500 000 units per hour. Echocardiography was performed in all patients at admission and after 3 and 7 days of treatment to evaluate intracardiac hemodynamics.Results. Both reperfusion methods significantly increase of ejection fraction (EF and maximal output speed of left ventricle (LV. Increase of LV EF in patients after PCA was higher than this in patients after STL. PCA improved LV diastolic function; STL did not change this characteristic. After PCA working diagnosis of ACS was transformed to the following final diagnosis: acute myocardial infarction (AMI with Q, AMI without Q and unstable angina in 37,5, 30,4 and 32,1% of patients, respectively. After STL diagnosis of AMI with Q was defined in all patients.Conclusion. PCA in patients with ACS with ST segment elevation results in fast improvement of global systolic and diastolic LV function. Besides, PCA prevents AMI with Q in a half of these patients.

"FACILS 2014: Microbially-driven facilitation systems in environmental biotechnology" (hereafter "FACILS") presented here by the European Commission (EC)-United States (US) Task Force on Biotechnology Research

Energy Technology Data Exchange (ETDEWEB)

Methe, Barbara

2016-02-03

As we enter the 21st century, the sustainability of the biosphere is a global challenge that can best be met with a global response. This includes how we train and promote our next generation of research scientists in the emerging arenas of genome-enabled biology and a bio-based economy. It is this fundamental issue that formed the motivation for designing and conducting a shortcourse entitled “FACILIS 2014: Microbially-driven facilitation systems in environmental biotechnology” (hereafter “FACILIS”) presented here by the European Commission (EC)-United States (US) Task Force on Biotechnology Research. This WG was established in 1994 under the umbrella of the US-EC Task Force on Biotechnology Research, a transatlantic collaborative group overseen by the US Office of Science and Technology Policy (OSTP) and the EC. The Environmental Biotechnology Working Group maintains several goals, including establishing research links between scientists in EU countries and the US and fostering the careers of junior scientists from both sides of the Atlantic to the global nature of scientific cooperation. To that end, a shortcourse was held at the University of Milan in Italy on July 12-25 2014 organized around cross-cutting themes of genomic science and designed to attract a stellar group of interdisciplinary early carrier researchers. A total of 22 students, 10 from the US and 12 from the EU participated. The course provided them with hands-on experience with the latest scientific methods in genomics and bioinformatics; using a format that combines lectures, laboratory research and field work with the final goal to enable researchers to finally turn data into knowledge.

S&T converging trends in dealing with disaster: A review on AI tools

International Nuclear Information System (INIS)

Hasan, Abu Bakar; Isa, Mohd Hafez Mohd.

2016-01-01

Science and Technology (S&T) has been able to help mankind to solve or minimize problems when arise. Different methodologies, techniques and tools were developed or used for specific cases by researchers, engineers, scientists throughout the world, and numerous papers and articles have been written by them. Nine selected cases such as flash flood, earthquakes, workplace accident, fault in aircraft industry, seismic vulnerability, disaster mitigation and management, and early fault detection in nuclear industry have been studied. This paper looked at those cases, and their results showed nearly 60% uses artificial intelligence (AI) as a tool. This paper also did some review that will help young researchers in deciding the types of AI tools to be selected; thus proving the future trends in S&T

S&T converging trends in dealing with disaster: A review on AI tools

Science.gov (United States)

Hasan, Abu Bakar; Isa, Mohd. Hafez Mohd.

2016-01-01

Science and Technology (S&T) has been able to help mankind to solve or minimize problems when arise. Different methodologies, techniques and tools were developed or used for specific cases by researchers, engineers, scientists throughout the world, and numerous papers and articles have been written by them. Nine selected cases such as flash flood, earthquakes, workplace accident, fault in aircraft industry, seismic vulnerability, disaster mitigation and management, and early fault detection in nuclear industry have been studied. This paper looked at those cases, and their results showed nearly 60% uses artificial intelligence (AI) as a tool. This paper also did some review that will help young researchers in deciding the types of AI tools to be selected; thus proving the future trends in S&T.

S&T converging trends in dealing with disaster: A review on AI tools

Energy Technology Data Exchange (ETDEWEB)

Hasan, Abu Bakar, E-mail: abakarh@usim.edu.my; Isa, Mohd Hafez Mohd. [Faculty of Science and Technology, Universiti Sains Islam Malaysia, 71800 Nilai, Negeri Sembilan (Malaysia)

2016-01-22

Science and Technology (S&T) has been able to help mankind to solve or minimize problems when arise. Different methodologies, techniques and tools were developed or used for specific cases by researchers, engineers, scientists throughout the world, and numerous papers and articles have been written by them. Nine selected cases such as flash flood, earthquakes, workplace accident, fault in aircraft industry, seismic vulnerability, disaster mitigation and management, and early fault detection in nuclear industry have been studied. This paper looked at those cases, and their results showed nearly 60% uses artificial intelligence (AI) as a tool. This paper also did some review that will help young researchers in deciding the types of AI tools to be selected; thus proving the future trends in S&T.

The Role of the st313-td Gene in Virulence of Salmonella Typhimurium ST313

DEFF Research Database (Denmark)

Herrero-Fresno, Ana; Wallrodt, Inke; Leekitcharoenphon, Pimlapas

2014-01-01

Multidrug-resistant Salmonella enterica serovar Typhimurium ST313 has emerged in sub-Saharan Africa causing severe infections in humans. Therefore, it has been speculated that this specific sequence type, ST313, carries factors associated with increased pathogenicity. We assessed the role in viru...

The Political Economy of Work in the 21st Century: Implications for an Aging American Workforce.

Science.gov (United States)

Sicker, Martin

The prospective place of the aging worker in the employment environment of the 21st century is examined. The following are among the specific topics discussed: (1) the real world of work and retirement; (2) the changing employment environment; (3) the restructuring of business in the United States; (4) globalization and the economy; (5) downsizing…

DEVELOPING THE 21ST-CENTURY SOCIAL STUDIES SKILLS THROUGH TECHNOLOGY INTEGRATION

Directory of Open Access Journals (Sweden)

Mohammad Imam FARISI

2016-01-01

Full Text Available Recently, technology has become an educational necessity in global-digital era. Facing these phenomena, social studies (SS should make innovations related to changes of 21st-century skills and learning paradigm, which is characterized by the principles of disclosure of information, computing, automation, and communication. Technology integration into SS learning is one of the learning innovations in the global-digital era, and powerfully supports the National Council for Social Studies (NCSS as stated in their visions: meaningful, powerful, value-based, challenging, and active. It also strongly supports the development of three core skills of the 21st-century, including learning and innovation skills; information, media and technology skills; life and career skills that developed in partnership with the Partnership Forum for 21st-Century Skills (P21. This paper examines and describes academics evolution toward a commitment and further developments in research; 21stcentury skills map for the SS; and the implications for developing teachers’ competences and teachers’ education curriculum.

Integration of a Miniaturized Conductivity Sensor into an Animal-Borne Instrument

Science.gov (United States)

2015-09-30

an Animal -Borne Instrument Lars Boehme Sea Mammal Research Unit Scottish Oceans Institute University of St Andrews St Andrews, KY16 8LB United... Kingdom phone: +44 1334-462677 fax: +44 1334-463443 email: lb284@st-andrews.ac.uk Robin Pascal Sensors Development Group National...Oceanography Centre Southampton, SO14 3ZY United Kingdom phone: +44 2380-596138 fax: +44 2380-593029 email: rwp@nerc.ac.uk Phil Lovell

ST-intuitionistic fuzzy metric space with properties

Science.gov (United States)

Arora, Sahil; Kumar, Tanuj

2017-07-01

In this paper, we define ST-intuitionistic fuzzy metric space and the notion of convergence and completeness properties of cauchy sequences is studied. Further, we prove some properties of ST-intuitionistic fuzzy metric space. Finally, we introduce the concept of symmetric ST Intuitionistic Fuzzy metric space.

PREFACE: 1st International School and Conference "Saint Petersburg OPEN 2014" on Optoelectronics, Photonics, Engineering and Nanostructures

Science.gov (United States)

2014-09-01

Dear Colleagues, 1st International School and Conference "Saint Petersburg OPEN 2014" on Optoelectronics, Photonics, Engineering and Nanostructures was held on March 25 - 27, 2014 at St. Petersburg Academic University - Nanotechnology Research and Education Centre of the Russian Academy of Sciences. The School and Conference included a series of invited talks given by leading professors with the aim to introduce young scientists with actual problems and major advances in physics and technology. The keynote speakers were: Mikhail Glazov (Ioffe Physico-Technical Institute RAS, Russia) Vladimir Dubrovskii (Saint Petersburg Academic University RAS, Russia) Alexey Kavokin (University of Southampton, United Kingdom and St. Petersburg State University, Russia) Vladimir Korenev (Ioffe Physico-Technical Institute RAS, Russia) Sergey Kukushkin (Institute of Problems of Mechanical Engineering RAS, Russia) Nikita Pikhtin (Ioffe Physico-Technical Institute RAS, Russia and "Elfolum" Ltd., Russia) Dmitry Firsov (Saint Petersburg State Polytechnical University, Russia) During the poster session all undergraduate and graduate students attending the conference presented their works. Sufficiently large number of participants with more than 160 student attendees from all over the world allowed the Conference to provide a fertile ground for the fruitful discussions between the young scientists as well as to become a perfect platform for the valuable discussions between student authors and highly experienced scientists. The best student papers, which were selected by the Program Committee and by the invited speakers basing on the theses and their poster presentation, were awarded with diplomas of the conference - see the photos. This year's School and Conference is supported by SPIE (The International Society for Optics and Photonics), OSA (The Optical Society), St. Petersburg State Polytechnical University and by Skolkovo Foundation. It is a continuation of the annual schools and

The GEOSS Science and Technology Stakeholder Network and Service Suite: Linking S&T Communities and GEOSS

Science.gov (United States)

Plag, Hans-Peter; Jules-Plag, Shelley

2015-04-01

The Global Earth Observation System of Systems (GEOSS) developed by the Group on Earth Observations (GEO) aims to provide practice-relevant knowledge in support of decision making in a wide range of societal benefit areas. Generating this practice-relevant knowledge based on Earth observations, socio-economic data and models often depends on research, and utilization of the societal benefits of EOs requires the involvement of science and research communities. Building a GEOSS responding to the needs of a wide range of users necessitates contributions from many science and technology (S&T) communities. In particular, a strong engagement of science and technology (S&T) communities in both the development and use of GEOSS is necessary to address the complex issues associated with the on-going transition out of the Holocene. S&T support is needed to improve interoperability between global observing, modeling, and information systems; to enable data integration across disciplinary boundaries; to facilitate data sharing, archiving, dissemination, and reanalysis; to optimize the recording of observations, assimilation of data into models, and generation of data products; to enhance the value of observations from individual observing systems through their integration in the SBAs; and to harmonize well-calibrated, highly accurate, stable, sustained in-situ and satellite observations of the same variable recorded by different sensors and different agencies. Consequently, the GEO Work Plan includes several Tasks focusing on outreach to S&T communities, and most of the GEO Community of Practice have a strong S&T component. The GEOSS S&T Stakeholder Network facilitates input from S&T communities to GEO. Infrastructure serving and linking S&T users communities and GEOSS has been developed and is integrated into a GEOSS S&T Service Suite (GSTSS). The GSTSS has several outreach components for the demonstration of GEOSS and its value for S&T communities, and for services supporting

1st October 2010 - Chinese Vice President of the Academy of Sciences signing the guest book and exchanging gifts with CERN Director for Research and Scientific Computing S. Bertolucci, witnessed by Adviser R. Voss

CERN Multimedia

Maximilien Brice

2010-01-01

1st October 2010 - Chinese Vice President of the Academy of Sciences signing the guest book and exchanging gifts with CERN Director for Research and Scientific Computing S. Bertolucci, witnessed by Adviser R. Voss

Quench tank in-leakage diagnosis at St. Lucie

International Nuclear Information System (INIS)

Price, J.E.; Au-Yang, M.K.; Beckner, D.A.; Vickery, A.N.

1996-01-01

In February 1995, leakage into the quench tank of the St. Lucie Nuclear Station Unit 1 was becoming an operational concern. This internal leak resulted in measurable increases in both the temperature and level of the quench tank water, and was so severe that, if the trend continued, plant shut down would be necessary. Preliminary diagnosis based on in-plant instrumentation indicated that any one of 11 valves might be leaking into the quench tank. This paper describes the joint effort by two teams of engineers--one from Florida Power ampersand Light, the other from Framatome Technologies--to identify the sources of the leak, using the latest technology developed for valve diagnosis

Vive la résistance: reviving resistance for 21st century conservation.

Science.gov (United States)

Nimmo, D G; Mac Nally, R; Cunningham, S C; Haslem, A; Bennett, A F

2015-09-01

Confronted with increasing anthropogenic change, conservation in the 21st century requires a sound understanding of how ecological systems change during disturbance. We highlight the benefits of recognizing two distinct components of change in an ecological unit (i.e., ecosystem, community, population): 'resistance', the ability to withstand disturbance; and 'resilience', the capacity to recover following disturbance. By adopting a 'resistance-resilience' framework, important insights for conservation can be gained into: (i) the key role of resistance in response to persistent disturbance, (ii) the intrinsic attributes of an ecological unit associated with resistance and resilience, (iii) the extrinsic environmental factors that influence resistance and resilience, (iv) mechanisms that confer resistance and resilience, (v) the post-disturbance status of an ecological unit, (vi) the nature of long-term ecological changes, and (vii) policy-relevant ways of communicating the ecological impacts of disturbance processes. Copyright © 2015 Elsevier Ltd. All rights reserved.

Job satisfaction and importance for intensive care unit research coordinators: results from binational survey.

Science.gov (United States)

Rickard, Claire M; Roberts, Brigit L; Foote, Jonathon; McGrail, Matthew R

2007-09-01

To measure Intensive Care Unit Research coordinator job satisfaction and importance and to identify priorities for role development. Research coordinator numbers are growing internationally in response to increasing clinical research activity. In Australia, 1% of registered nurses work principally in research, many as Research coordinators. Internationally, the Association of Clinical Research Professionals currently has 6536 certified Research coordinators in 13 countries, with likely additional large numbers practicing without the voluntary certification. Research coordinators are almost always nurses, but little is know about this emerging specialty. Design. Cross-sectional study using anonymous self-report questionnaire. After ethics approval, the McCloskey-Mueller Satisfaction Scale and McCloskey-Mueller Importance Scale were administered via the Internet. The sample was 49 (response rate 71%) Research coordinators from the Australia and New Zealand Intensive Care Unit Research coordinators' Interest Group. Research coordinators were satisfied with structural aspects of the position working business hours; flexibility of working hours; high levels of responsibility and control over their work. Dissatisfaction was expressed regarding: remuneration and recognition; compensation for weekend work; salary package; career advancement opportunities; and childcare facilities. High priorities for role development are those rated highly important but with much lower satisfaction. These are: compensation for weekend call-out work; salary and remuneration package; recognition by management and clinicians; career advancement opportunities; departmental research processes; encouragement and feedback; and number of working hours. Increasing numbers of nurses have been attracted to this clinically based research position. These data contribute to the understanding and development of the role.

Science, technology, engineering, mathematics (STEM) as mathematics learning approach in 21st century

Science.gov (United States)

Milaturrahmah, Naila; Mardiyana, Pramudya, Ikrar

2017-08-01

This 21st century demands competent human resources in science, technology, engineering design and mathematics so that education is expected to integrate the four disciplines. This paper aims to describe the importance of STEM as mathematics learning approach in Indonesia in the 21st century. This paper uses a descriptive analysis research method, and the method reveals that STEM education growing in developed countries today can be a framework for innovation mathematics in Indonesia in the 21st century. STEM education integrate understanding of science, math skills, and the available technology with the ability to perform engineering design process. Implementation of mathematics learning with STEM approach makes graduates trained in using of mathematics knowledge that they have to create innovative products that are able to solve the problems that exist in society.

Henkilöstövoimavarojen johtamista megamarketissa

OpenAIRE

Setälä, Minna

2016-01-01

Henkilöstö on lähes kaikkien organisaatioiden tärkein voimavara ja menestyksen perusta. Ilman henkilöstön olemassaoloa ja osaamista, ei mikään organisaatio pystyisi toimimaan. Henkilöstövoimavarojen johtamisen tulisikin olla keskeinen osa yrityksen strategista toimintaa. Osaava ja hyvinvoiva henkilöstö tuottaa luonnollisesti vastinetta siihen sijoitetulle pääomalle. Tämä opinnäytetyö tehtiin Vantaalla sijaitsevalle elintarvike- ja päivittäistavaraketjun myymälälle, supermarketille. Tavo...

Radioactivity and United Kingdom estuaries: an overview identifying research priorities

International Nuclear Information System (INIS)

Hamilton, E.I.; Clifton, R.J.; Stevens, H.E.

1985-05-01

The report consists of the results of an evaluation of research priorities for the environmental radioactivity of estuaries, (and near shore waters) of the United Kingdom. The format of this report is:(i) general conclusions for the future requirements for research in the field of environmental radioactivity; (ii) an overview of some specific recommendations for research; and (iii) an appendix in which a comprehensive evaluation of the research priorities for specific areas of research are given. On the basis that man is the prime target for concern and protection, special attention has been given to the environment in the vicinity of the British Nuclear Fuels (BNFL) reprocessing plant at Sellafield, Cumbria, which is the source of major releases of a variety of radionuclides into the natural environment. Subjects covered in the Appendix are: site factors; pathways to man; source term; hot particles; terrestrial inputs; surveys and monitoring; analysis; organics; field versus laboratory data; biology; bioaccumulation factors; some bioaccumulators of radioactivity; bioturbation; bacteria; genetics; natural change; sediment; resuspension; surfaces; Ksub(d) factors; pore liquids; diagenesis and the ageing processes; airborne transport of radionuclides; models; natural radioactivity; public opinion; recreation; the ICRP; the ALARA principle; decommissioning of nuclear power stations; identification of research requirements; environmental radioactivity - the national effort. (U.K.)

School Censorship in the 21st Century: A Guide for Teachers and School Library Media Specialists.

Science.gov (United States)

Simmons, John S.; Dresang, Eliza T.

As the world enters the 21st century, the access to information and freedom of speech provided by the Internet and other digital technologies have revolutionized the nature of censorship challenges and opened an entirely new realm of legal and social ramifications for censorship in United States schools. In the midst of this digital revolution,…

Baseline risk assessment for exposure to contaminants at the St. Louis Site, St. Louis, Missouri

International Nuclear Information System (INIS)

1993-11-01

The St. Louis Site comprises three noncontiguous areas in and near St. Louis, Missouri: the St. Louis Downtown Site (SLDS), the St. Louis Airport Storage Site (SLAPS), and the Latty Avenue Properties. The main site of the Latty Avenue Properties includes the Hazelwood Interim Storage Site (HISS) and the Futura Coatings property, which are located at 9200 Latty Avenue. Contamination at the St. Louis Site is the result of uranium processing and disposal activities that took place from the 1940s through the 1970s. Uranium processing took place at the SLDS from 1942 through 1957. From the 1940s through the 1960s, SLAPS was used as a storage area for residues from the manufacturing operations at SLDS. The materials stored at SLAPS were bought by Continental Mining and Milling Company of Chicago, Illinois, in 1966, and moved to the HISS/Futura Coatings property at 9200 Latty Avenue. Vicinity properties became contaminated as a result of transport and movement of the contaminated material among SLDS, SLAPS, and the 9200 Latty Avenue property. This contamination led to the SLAPS, HISS, and Futura Coatings properties being placed on the National Priorities List (NPL) of the US Environmental Protection Agency (EPA). The US Department of Energy (DOE) is responsible for cleanup activities at the St. Louis Site under its Formerly Utilized Sites Remedial Action Program (FUSRAP). The primary goal of FUSRAP is the elimination of potential hazards to human health and the environment at former Manhattan Engineer District/Atomic Energy Commission (MED/AEC) sites so that, to the extent possible, these properties can be released for use without restrictions. To determine and establish cleanup goals for the St. Louis Site, DOE is currently preparing a remedial investigation/feasibility study-environmental impact statement (RI/FS-EIS). This baseline risk assessment (BRA) is a component of the process; it addresses potential risk to human health and the environment associated wi

Herrens röst

DEFF Research Database (Denmark)

Rösing, Lilian Munk

2015-01-01

Om språket är gränsen mellan djur och människor, vad innebär det när hundar talar? I filmen Upp pratar de animerade hundarna, men med sin husses röst. Lilian Munk Rösing ser filmen i sällskap av bland andra Jacques Lacan, Slavoj Žižek och Renata Salecl och finner en röst utan kropp, en kropp besj...

Research on unit commitment with large-scale wind power connected power system

Science.gov (United States)

Jiao, Ran; Zhang, Baoqun; Chi, Zhongjun; Gong, Cheng; Ma, Longfei; Yang, Bing

2017-01-01

Large-scale integration of wind power generators into power grid brings severe challenges to power system economic dispatch due to its stochastic volatility. Unit commitment including wind farm is analyzed from the two parts of modeling and solving methods. The structures and characteristics can be summarized after classification has been done according to different objective function and constraints. Finally, the issues to be solved and possible directions of research and development in the future are discussed, which can adapt to the requirements of the electricity market, energy-saving power generation dispatching and smart grid, even providing reference for research and practice of researchers and workers in this field.

Differences in symptoms, first medical contact and pre-hospital delay times between patients with ST- and non-ST-elevation myocardial infarction.

Science.gov (United States)

Ängerud, Karin H; Sederholm Lawesson, Sofia; Isaksson, Rose-Marie; Thylén, Ingela; Swahn, Eva

2017-11-01

In ST-elevation myocardial infarction, time to reperfusion is crucial for the prognosis. Symptom presentation in myocardial infarction influences pre-hospital delay times but studies about differences in symptoms between patients with ST-elevation myocardial infarction and non-ST-elevation myocardial infarction are sparse and inconclusive. The aim was to compare symptoms, first medical contact and pre-hospital delay times in patients with ST-elevation myocardial infarction and non-ST-elevation myocardial infarction. This multicentre, observational study included 694 myocardial infarction patients from five hospitals. The patients filled in a questionnaire about their pre-hospital experiences within 24 h of hospital admittance. Chest pain was the most common symptom in ST-elevation myocardial infarction and non-ST-elevation myocardial infarction (88.7 vs 87.0%, p=0.56). Patients with cold sweat (odds ratio 3.61, 95% confidence interval 2.29-5.70), jaw pain (odds ratio 2.41, 95% confidence interval 1.04-5.58), and nausea (odds ratio 1.70, 95% confidence interval 1.01-2.87) were more likely to present with ST-elevation myocardial infarction, whereas the opposite was true for symptoms that come and go (odds ratio 0.58, 95% confidence interval 0.38-0.90) or anxiety (odds ratio 0.52, 95% confidence interval 0.29-0.92). Use of emergency medical services was higher among patients admitted with ST-elevation myocardial infarction. The pre-hospital delay time from symptom onset to first medical contact was significantly longer in non-ST-elevation myocardial infarction (2:05 h vs 1:10 h, p=0.001). Patients with ST-elevation myocardial infarction differed from those with non-ST-elevation myocardial infarction regarding symptom presentation, ambulance utilisation and pre-hospital delay times. This knowledge is important to be aware of for all healthcare personnel and the general public especially in order to recognise symptoms suggestive of ST-elevation myocardial infarction and

The Differences in the Feast Day of St. Onnohprius the Great

Directory of Open Access Journals (Sweden)

Voitenko Anton

2016-02-01

Full Text Available The article investigates the differences in the feast day of a famous Egyptian hermit St. Onnophrius the Great (the 4th century. In Christian traditions a few dates of St. Onnophrius’ celebration are known, the most common ones are three: 10, 11 and 12 June after the Julian calendar. These dates, which are close to each other, cannot point out some diff erent and independent church traditions in veneration of the saint, more likely they conjecture an error or an intentional slight transference of his feast day in some Christian Churches. Date June 10 corresponds to Paone 16 after the Coptic calendar and it is a day of remembrance of St. Onnophrius in the Coptic Church. The reasons for this discrepancy have not been studied to the present day. The author through his analysis of unpublished manuscripts has established the origin of the date June 11, as well as he has suggested the causes of the rise of the date June 12. All other known days of St. Onnohprius’ commemoration (6, 8, 9, 13 and 17 June can be considered like «marginal» ones and their origins require additional research based on other sources.

ALARA and decommissioning: The Fort St. Vrain experience

Energy Technology Data Exchange (ETDEWEB)

Borst, T.; Niehoff, M. [Public Service Co. of Colorado, Platteville, CO (United States); Zachary, M. [Scientific Ecology Group, Platteville, CO (United States)

1995-03-01

The Fort St. Vrain Nuclear Generating Station, the first and only commercial High Temperature Gas Cooled Reactor to operate in the United States, completed initial fuel loading in late 1973 and initial startup in early 1974. Due to a series of non-nuclear technical problems, Fort St. Vrain never operated consistently, attaining a lifetime capacity factor of slightly less than 15%. In August of 1989, the decision was made to permanently shut down the plant due to control rod drive and steam generator ring header failures. Public Service Company of Colorado elected to proceed with early dismantlement (DECON) as opposed to SAFSTOR on the bases of perceived societal benefits, rad waste, and exposure considerations, regulatory uncertainties associated with SAFSTOR, and cost. The decommissioning of Fort St. Vrain began in August of 1992, and is scheduled to be completed in early 1996. Decommissioning is being conducted by a team consisting of Westinghouse, MK-Ferguson, and Scientific Ecology Group. Public Service Company of Colorado as the licensee provides contract management and oversight of contractor functions. An aggressive program to maintain project radiation exposures As Low As Reasonably Achievable (ALARA) has been established, with the following program elements: temporary and permanent shielding contamination control; mockup training; engineering controls; worker awareness; integrated work package reviews communication; special instrumentation; video camera usage; robotics application; and project committees. To date, worker exposures have been less than project estimates. from the start of the project through Februrary of 1994, total exposure has been 98.666 person-rem, compared to the project estimate of 433 person-rem and goal of 347 person-rem. The presentation will discuss the site characterization efforts, the radiological performance indicator program, and the final site release survey plans.

1st International Conference on Advancements of Medical Electronics

CERN Document Server

Bag, Sandip; Ganguly, Karabi; Sarkar, Indranath; Biswas, Papun

2015-01-01

The book is a collection of peer-reviewed scientific papers submitted by active researchers in the 1st International Conference on Advancements of Medical Electronics (ICAME2015). The conference is organized jointly by the Department of Biomedical Engineering and Electronics and Communication Engineering, JIS College of Engineering, West Bengal, India. The primary objective of the conference is to strengthen interdisciplinary research and its applications for the welfare of humanity. A galaxy of academicians, professionals, scientists, statesman and researchers from different parts of the country and abroad got together and shared their knowledge. The book presents research articles of medical image processing & analysis, biomedical instrumentation & measurements, DSP & clinical applications, embedded systems & its applications in healthcare. The book can be referred as a tool for further research.

Overview of feedstock research in the United States, Canada, and Brazil

Energy Technology Data Exchange (ETDEWEB)

Ferrell, J. [Department of Energy, Washington, DC (United States); Tardif, M.L. [CANMET, Ottawa, Ontario (Canada); Couto, L. [Universidade Federal de Vicosa (Brazil); Garca, L.R. [Centro Nacional de Pesquisa de Florestas, Colombo (Brazil); Betters, D. [Colorado State Univ., Fort Collins, CO (United States); Ashworth, J. [Meridian Corp., Alexandria, VA (United States)

1993-12-31

This is an overview of the current biomass feedstock efforts in Brazil, Canada, and the United States. The report from Brazil provides an historical perspective of incentive programs, the charcoal and fuelwood energy programs, the alcohol program, and other biomass energy efforts. The efforts in Brazil, particularly with the sugar cane to ethanol and the charcoal and fuelwood programs, dwarfs other commercial biomass systems in the Americas. One of the bright spots in the future is the Biomass Integrated Gasification/Gas Turbine Electricity Project initially funded in 1992. The sugar cane-based ethanol industry continues to develop higher yielding cane varieties and more efficient microorganisms to convert the sugar cane carbohydrates into alcohol. In Canada a number of important institutions and enterprises taking part in the economical development of the country are involved in biomass research and development including various aspects of the biomass such as forestry, agricultural, industrial, urban, food processing, fisheries and peat bogs. Biomass feedstock research in the United States is evolving to reflect Department of Energy priorities. Greater emphasis is placed on leveraging research with the private sector contributing a greater share of funds, for both research and demonstration projects. The feedstock program, managed by ORNL, is focused on limited model species centered at a regional level using a multidisciplinary approach. Activities include a stronger emphasis on emerging environmental issues such as biodiversity, sustainability and habitat management. DOE also is a supporter of the National Biofuels Roundtable, which is developing principles for producing biomass energy in an economically viable and ecologically sound manner. Geographical Information Systems are also being developed as tools to quantify and characterize the potential supply of energy crops in various regions.

Identification and characterization of two novel cytosolic sulfotransferases, SULT1 ST7 and SULT1 ST8, from zebrafish

Energy Technology Data Exchange (ETDEWEB)

Liu, T.-A. [Department of Pharmacology, College of Pharmacy, University of Toledo, Toledo, OH 43606 (United States); Department of Biological Science and Technology, College of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan (China); Bhuiyan, Shakhawat [Division of Arts and Sciences, Jarvis Christian College, Hawkins, TX 75765 (United States); Snow, Rhodora [School of Mathematics and Science, J. Sargeant Reynolds Community College, Richmond, VA 23285 (United States); Yasuda, Shin; Yasuda, Tomoko [Department of Pharmacology, College of Pharmacy, University of Toledo, Toledo, OH 43606 (United States); Yang, Y.-S. [Department of Biological Science and Technology, College of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan (China); Williams, Frederick E.; Liu, M.-Y.; Suiko, Masahito [Department of Pharmacology, College of Pharmacy, University of Toledo, Toledo, OH 43606 (United States); Carter, Glendora [School of Mathematics and Science, J. Sargeant Reynolds Community College, Richmond, VA 23285 (United States); Liu, M.-C. [Department of Pharmacology, College of Pharmacy, University of Toledo, Toledo, OH 43606 (United States)], E-mail: ming.liu@utoledo.edu

2008-08-29

Cytosolic sulfotransferases (SULTs) constitute a family of Phase II detoxification enzymes that are involved in the protection against potentially harmful xenobiotics as well as the regulation and homeostasis of endogenous compounds. Compared with humans and rodents, the zebrafish serves as an excellent model for studying the role of SULTs in the detoxification of environmental pollutants including environmental estrogens. By searching the expressed sequence tag database, two zebrafish cDNAs encoding putative SULTs were identified. Sequence analysis indicated that these two putative zebrafish SULTs belong to the SULT1 gene family. The recombinant form of these two novel zebrafish SULTs, designated SULT1 ST7 and SULT1 ST8, were expressed using the pGEX-2TK glutathione S-transferase (GST) gene fusion system and purified from transformed BL21 (DE3) cells. Purified GST-fusion protein form of SULT1 ST7 and SULT1 ST8 exhibited strong sulfating activities toward environmental estrogens, particularly hydroxylated polychlorinated biphenyls (PCBs), among various endogenous and xenobiotic compounds tested as substrates. pH-dependence experiments showed that SULT1 ST7 and SULT1 ST8 displayed pH optima at 6.5 and 8.0, respectively. Kinetic parameters of the two enzymes in catalyzing the sulfation of catechin and chlorogenic acid as well as 3-chloro-4-biphenylol were determined. Developmental expression experiments revealed distinct patterns of expression of SULT1 ST7 and SULT1 ST8 during embryonic development and throughout the larval stage onto maturity.

Characterization of seasonal reproduction in Virginia Tech Selection Line, St. Croix, and Suffolk ewes

OpenAIRE

Jordan, Katherine Mead

2008-01-01

This dissertation research contained three studies. The first two studies were conducted to investigate the ability of ewes to rebreed while lactating during seasonal anestrus. Breeds studied included the Virginia Tech Out-of-season (OOS) Line, which is a wool line genetically selected to lamb in the fall, and the St. Croix, a hair breed of tropical origin thought to be lowly seasonal. When January-lambing ewes were exposed to rams while lactating in April, significantly more OOS than St. ...

The Entrance test of physics and Workbook in teaching of physics at secondary vocational school within long-term pedagogical research

Science.gov (United States)

Kerlínová, Věra

2017-01-01

Within the long-term pedagogical research ongoing since the school year 2008/2009 to 2015/2016 at the secondary vocational school in Bohumín was through of Entrance test of physics, which included curriculum of the sixth to ninth year of elementary school, regularly finding out, in which parts of Entrance test - Unit conversions, International System of Units, Properties of matter, Mechanics, Thermodynamics, Electricity and Magnetism, Optics, Atoms and Universe - pupils of the 1st years of secondary vocational school, technical and non-technical, reach a higher number of correct answers, in which dominates the wrong answers and which parts of the test pupils are better left out completely. It turned out that the results of these tests are very informative not only for theoretical and practical teaching, but also technical and other science subjects. The results of the Entrance tests are also a valuable source of information for continuous innovation Workbook of Physics - Mechanics for the 1st year of secondary vocational schools [1] - whose the first version began during the school year 2007/2008 and which was tested within pre-research in school years 2008/2009, 2009/2010 and within research in school year 2010/2011. On the basis of feedbacks getting from research the Workbook is regularly expanded, innovated and updated. The Workbook consists of parts dedicated to physical concepts, physical tasks, proposals to physical experiments, pupils comments from viewed video projection and documentary films, examples from the world of science and technology, examples from practice and real life, physical terminology in English, quizzes, competitions, interesting things and links related to discussed curriculum. The Workbook is divided into thematic sections, chapters and subchapters similar as physics textbooks for pupils of the 1st years of Secondary Schools in the Czech Republic. In the Workbook there are included tasks on fill in the words, polynomial tasks with

Rock-Mechanics Research. A Survey of United States Research to 1965, with a Partial Survey of Canadian Universities.

Science.gov (United States)

National Academy of Sciences - National Research Council, Washington, DC.

The results of a survey, conducted by the Committee on Rock Mechanics, to determine the status of training and research in rock mechanics in presented in this publication. In 1964 and 1965 information was gathered by questionnaires sent to industries, selected federal agencies, and universities in both the United States and Canada. Results are…

Rapakivi Granite: An architectural emblem of St Petersburg and its utilisation in other world cities

Science.gov (United States)

Bulakh, Andrey; Gavrilenko, Vladimir; Panova, Helen

2015-04-01

The wide-ranging utilisation of Rapakivi Granite in St Petersburg is typified by the the famous Alexander Column, and 114 stone columns of St Isaac's Cathedralas well as the pedestal of the Nicholas I monument, and portals and basements of buildings of the Admiralty, General Staff, Senate and Synod. The stone is also frequently seen among pavement slabs and in parapets of embankments and bridges around the city. This list of examples where Rapakivi Granite has been used could be expanded further. All Rapakivi Granites used in the buildings of St.Petersburg were quarried from the so-called Vyborg massif. At present it has been found that the massif occupies an area of about 18 000 km2. In the past granite of the Vyborg massif was worked from several quarries in the vicinity of Fredrikshamn (Hamina) in Finland for use in St Peterburg. The best known granite quarries are at Piterlaks (Piuterlahti) and Gimmekyul (Hämeenkylä). Sometimes Rapakivi Granite form Finland differs in appearance from typical varieties. Thus columns of a classical portal in the house at N 7 in Pochtamtskaya Street are hewn from this greyish variety. Other examples are the plinth of the General Staff and Trade Store buildings. After the 1960s varieties from the Leningrad district, and Korosten (Ukraine) massifs were used in St Petersburg. Today it is possible to find examples of Rapakivi Granite from Finland in cities in the USA, South Africa, United Kingdom and Germany. It is a long used stone as demonstrated by its cultural heritage. It is also used as an ornamental or decorative stone in modern architecture. References: 1) Bulakh, A.G., Abakumova, N.B., and Romanovsky, J.V. St Petersburg: a History in Stone. 2010. Print House of St Petersburg State University. 173 p. (In English). 2) Tutakova, A.Ya., Romanovskiy, A.Z., Bulakh, A.G., and Leer, V.I. Dimension Stone of the Leningrad Region. Granites of the Karelia Isthmus in Architecture of the Modern St Petersburg. 2011. St Petersburg. 78 p

Safety evaluation report related to the operation of St. Lucie Plant, Unit No. 2, Docket No. 50-389. Florida Power and Light Company, Orlando Utilities Commission of the City of Orlando, Florida

International Nuclear Information System (INIS)

1982-09-01

On October 9, 1981, the Nuclear Regulatory Commission (NRC) staff issued a safety evaluation report (SER) related to the operation of St. Lucie Plant Unit 2. Supplement No. 1 (SSER 1) to the SER was issued in December, 1981. In the SER and SSER 1 the staff identified certain issues where either further information or additional staff effort was necessary to complete the review. The purpose of this supplement is to update the SER by providing (1) evaluation of additional information submitted by the applicant since SSER 1 to the SER was issued and (2) evaluation of the matters the staff had under review when the SSER 1 was issued

St. James marine terminal facility description

Energy Technology Data Exchange (ETDEWEB)

1993-10-01

The US Department of Energy (DOE) currently owns and operates a marine terminal on the west bank of the Mississippi River at St. James, Louisiana. The St. James facility was constructed by the Department to provide marine services associated with the fill and drawdown of the Strategic Petroleum Reserve (SPR) crude oil storage facilities located at Bayou Choctaw and Weeks Island, Louisiana. Although strategic to the mission of the SPR in the event of a national emergency, the St. James terminal is situated such that it has a high potential to also serve the commercial industry`s needs for crude oil terminalling and storage. The St. James terminal is located approximately 45 miles west of New Orleans and 30 miles southeast of Baton Rouge, and approximately 160 miles upstream from the mouth of the Mississippi River. Construction of the St. James terminal was initiated in 1978 and was completed in 1980. Since then, the terminal has received and transferred over 125 million barrels of crude oil to the SPR sites for storage. For crude oil distribution, the St. James terminal was connected to the neighboring LOCAP terminal by a 0.1 mile 36-inch pipeline in 1981 and to the Capline terminal by a 0.5 mile 30-inch pipeline in 1988. The terminal also has a 30-inch pipeline connection to the Koch oil terminal which was used for initial fill purposes; however, this pipeline has been disconnected and is currently inactive. A complete description of the St. James terminal facilities, operational capabilities, operational certifications, and future Government requirements are presented in Sections 2, 3, 4, and 5 respectively.

Evidence-based toxicology for the 21st century: opportunities and challenges.

Science.gov (United States)

Stephens, Martin L; Andersen, Melvin; Becker, Richard A; Betts, Kellyn; Boekelheide, Kim; Carney, Ed; Chapin, Robert; Devlin, Dennis; Fitzpatrick, Suzanne; Fowle, John R; Harlow, Patricia; Hartung, Thomas; Hoffmann, Sebastian; Holsapple, Michael; Jacobs, Abigail; Judson, Richard; Naidenko, Olga; Pastoor, Tim; Patlewicz, Grace; Rowan, Andrew; Scherer, Roberta; Shaikh, Rashid; Simon, Ted; Wolf, Douglas; Zurlo, Joanne

2013-01-01

The Evidence-based Toxicology Collaboration (EBTC) was established recently to translate evidence-based approaches from medicine and health care to toxicology in an organized and sustained effort. The EBTC held a workshop on "Evidence-based Toxicology for the 21st Century: Opportunities and Challenges" in Research Triangle Park, North Carolina, USA on January 24-25, 2012. The presentations largely reflected two EBTC priorities: to apply evidence-based methods to assessing the performance of emerging pathway-based testing methods consistent with the 2007 National Research Council report on "Toxicity Testing in the 21st Century" as well as to adopt a governance structure and work processes to move that effort forward. The workshop served to clarify evidence-based approaches and to provide food for thought on substantive and administrative activities for the EBTC. Priority activities include conducting pilot studies to demonstrate the value of evidence-based approaches to toxicology, as well as conducting educational outreach on these approaches.

Predicting nonstationary flood frequencies: Evidence supports an updated stationarity thesis in the United States

Science.gov (United States)

Luke, Adam; Vrugt, Jasper A.; AghaKouchak, Amir; Matthew, Richard; Sanders, Brett F.

2017-07-01

Nonstationary extreme value analysis (NEVA) can improve the statistical representation of observed flood peak distributions compared to stationary (ST) analysis, but management of flood risk relies on predictions of out-of-sample distributions for which NEVA has not been comprehensively evaluated. In this study, we apply split-sample testing to 1250 annual maximum discharge records in the United States and compare the predictive capabilities of NEVA relative to ST extreme value analysis using a log-Pearson Type III (LPIII) distribution. The parameters of the LPIII distribution in the ST and nonstationary (NS) models are estimated from the first half of each record using Bayesian inference. The second half of each record is reserved to evaluate the predictions under the ST and NS models. The NS model is applied for prediction by (1) extrapolating the trend of the NS model parameters throughout the evaluation period and (2) using the NS model parameter values at the end of the fitting period to predict with an updated ST model (uST). Our analysis shows that the ST predictions are preferred, overall. NS model parameter extrapolation is rarely preferred. However, if fitting period discharges are influenced by physical changes in the watershed, for example from anthropogenic activity, the uST model is strongly preferred relative to ST and NS predictions. The uST model is therefore recommended for evaluation of current flood risk in watersheds that have undergone physical changes. Supporting information includes a MATLAB® program that estimates the (ST/NS/uST) LPIII parameters from annual peak discharge data through Bayesian inference.

1st Applied Electromagnetic International Conference

CERN Document Server

Othman, Mohd; Aziz, Mohamad; Malek, Mohd

2015-01-01

In this book, experts from academia and industry present the latest advances in scientific theory relating to applied electromagnetics and examine current and emerging applications particularly within the fields of electronics, communications, and computer technology. The book is based on presentations delivered at APPEIC 2014, the 1st Applied Electromagnetic International Conference, held in Bandung, Indonesia in December 2014. The conference provided an ideal platform for researchers and specialists to deliver both theoretically and practically oriented contributions on a wide range of topics relevant to the theme of nurturing applied electromagnetics for human technology. Many novel aspects were addressed, and the contributions selected for this book highlight the relevance of advances in applied electromagnetics to a variety of industrial engineering problems and identify exciting future directions for research.

Pre-Service Physics Teachers’ Perception toward Hands-on Lab Activity and 21st Century Skills

Science.gov (United States)

Putri, D. H.; Risdianto, E.; Sutarno, S.

2017-09-01

This study aimed to describe the hands-on lab activities and 21st century skills of pre-service physics teachers at a university in Bengkulu. The respondents of this study were 113 students who have been finished and were following the laboratory course. The research instrument was questionnaire. The explored aspects of laboratory activities were motivation, the importance of laboratory activities, equipment, laboratory activities process, suitability of curriculum, assessment, laboratory design, and the 21st century skills training. The 21st century skills explored consist of learning and innovation skills, life and careers skills, and media, information and technology skills. The data obtained will be analyzed descriptively. Based on the results of data analysis was obtained that they have a good perception toward the aspect of motivation, the importance of hands-on lab activities, and laboratory activities process; and the perception was fair for other aspects. The lowest perception score was obtained in the aspects of the 21st century skills training. This result was in accordance with the 21st century skills of pre-service physics teachers which were still in moderate category. So it is necessary to develop a model of laboratory activities design that can training and enhancing the 21st century skills for pre-service physics teachers.

Transforming Epidemiology for 21st Century Medicine and Public Health

Science.gov (United States)

Khoury, Muin J.; Lam, Tram Kim; Ioannidis, John P.A.; Hartge, Patricia; Spitz, Margaret R.; Buring, Julie E.; Chanock, Stephen J.; Croyle, Robert T.; Goddard, Katrina A.; Ginsburg, Geoffrey S.; Herceg, Zdenko; Hiatt, Robert A.; Hoover, Robert N.; Hunter, David J.; Kramer, Barnet S.; Lauer, Michael S.; Meyerhardt, Jeffrey A.; Olopade, Olufunmilayo I.; Palmer, Julie R.; Sellers, Thomas A.; Seminara, Daniela; Ransohoff, David F.; Rebbeck, Timothy R.; Tourassi, Georgia; Winn, Deborah M.; Zauber, Ann; Schully, Sheri D.

2013-01-01

In 2012, the National Cancer Institute (NCI) engaged the scientific community to provide a vision for cancer epidemiology in the 21st century. Eight overarching thematic recommendations, with proposed corresponding actions for consideration by funding agencies, professional societies, and the research community emerged from the collective intellectual discourse. The themes are (i) extending the reach of epidemiology beyond discovery and etiologic research to include multilevel analysis, intervention evaluation, implementation, and outcomes research; (ii) transforming the practice of epidemiology by moving towards more access and sharing of protocols, data, metadata, and specimens to foster collaboration, to ensure reproducibility and replication, and accelerate translation; (iii) expanding cohort studies to collect exposure, clinical and other information across the life course and examining multiple health-related endpoints; (iv) developing and validating reliable methods and technologies to quantify exposures and outcomes on a massive scale, and to assess concomitantly the role of multiple factors in complex diseases; (v) integrating “big data” science into the practice of epidemiology; (vi) expanding knowledge integration to drive research, policy and practice; (vii) transforming training of 21st century epidemiologists to address interdisciplinary and translational research; and (viii) optimizing the use of resources and infrastructure for epidemiologic studies. These recommendations can transform cancer epidemiology and the field of epidemiology in general, by enhancing transparency, interdisciplinary collaboration, and strategic applications of new technologies. They should lay a strong scientific foundation for accelerated translation of scientific discoveries into individual and population health benefits. PMID:23462917

St. Brendan's High Support Unit, Mulranny, Westport, Mayo.

LENUS (Irish Health Repository)

Sheehan, Aisling

2015-02-01

Nursing is experiencing a significant deficit in research capacity needed to meet future global healthcare demands-there is a call to double the number of nurses and healthcare professionals with a doctorate.

Involvement of consumers in studies run by the Medical Research Council Clinical Trials Unit: Results of a survey

Directory of Open Access Journals (Sweden)

Vale Claire L

2012-01-01

Full Text Available Abstract Background We aimed to establish levels of consumer involvement in randomised controlled trials (RCTs, meta-analyses and other studies carried out by the UK Medical Research Council (MRC Clinical Trials Unit across the range of research programs, predominantly in cancer and HIV. Methods Staff responsible for studies that were included in a Unit Progress Report (MRC CTU, April 2009 were asked to complete a semi-structured questionnaire survey regarding consumer involvement. This was defined as active involvement of consumers as partners in the research process and not as subjects of that research. The electronic questionnaires combined open and closed questions, intended to capture quantitative and qualitative information on whether studies had involved consumers; types of activities undertaken; recruitment and support; advantages and disadvantages of involvement and its perceived impact on aspects of the research. Results Between October 2009 and April 2010, 138 completed questionnaires (86% were returned. Studies had been conducted over a 20 year period from 1989, and around half were in cancer; 30% in HIV and 20% were in other disease areas including arthritis, tuberculosis and blood transfusion medicine. Forty-three studies (31% had some consumer involvement, most commonly as members of trial management groups (TMG [88%]. A number of positive impacts on both the research and the researcher were identified. Researchers generally felt involvement was worthwhile and some felt that consumer involvement had improved the credibility of the research. Benefits in design and quality, trial recruitment, dissemination and decision making were also perceived. Researchers felt they learned from consumer involvement, albeit that there were some barriers. Conclusions Whilst most researchers identified benefits of involving consumers, most of studies included in the survey had no involvement. Information from this survey will inform the development

Involvement of consumers in studies run by the Medical Research Council Clinical Trials Unit: results of a survey.

Science.gov (United States)

Vale, Claire L; Thompson, Lindsay C; Murphy, Claire; Forcat, Silvia; Hanley, Bec

2012-01-13

We aimed to establish levels of consumer involvement in randomised controlled trials (RCTs), meta-analyses and other studies carried out by the UK Medical Research Council (MRC) Clinical Trials Unit across the range of research programs, predominantly in cancer and HIV. Staff responsible for studies that were included in a Unit Progress Report (MRC CTU, April 2009) were asked to complete a semi-structured questionnaire survey regarding consumer involvement. This was defined as active involvement of consumers as partners in the research process and not as subjects of that research. The electronic questionnaires combined open and closed questions, intended to capture quantitative and qualitative information on whether studies had involved consumers; types of activities undertaken; recruitment and support; advantages and disadvantages of involvement and its perceived impact on aspects of the research. Between October 2009 and April 2010, 138 completed questionnaires (86%) were returned. Studies had been conducted over a 20 year period from 1989, and around half were in cancer; 30% in HIV and 20% were in other disease areas including arthritis, tuberculosis and blood transfusion medicine. Forty-three studies (31%) had some consumer involvement, most commonly as members of trial management groups (TMG) [88%]. A number of positive impacts on both the research and the researcher were identified. Researchers generally felt involvement was worthwhile and some felt that consumer involvement had improved the credibility of the research. Benefits in design and quality, trial recruitment, dissemination and decision making were also perceived. Researchers felt they learned from consumer involvement, albeit that there were some barriers. Whilst most researchers identified benefits of involving consumers, most of studies included in the survey had no involvement. Information from this survey will inform the development of a unit policy on consumer involvement, to guide future

Meteor detection on ST (MST) radars

International Nuclear Information System (INIS)

Avery, S.K.

1987-01-01

The ability to detect radar echoes from backscatter due to turbulent irregularities of the radio refractive index in the clear atmosphere has lead to an increasing number of established mesosphere - stratosphere - troposphere (MST or ST) radars. Humidity and temperature variations are responsible for the echo in the troposphere and stratosphere and turbulence acting on electron density gradients provides the echo in the mesosphere. The MST radar and its smaller version, the ST radar, are pulsed Doppler radars operating in the VHF - UHF frequency range. These echoes can be used to determine upper atmosphere winds at little extra cost to the ST radar configuration. In addition, the meteor echoes can supplement mesospheric data from an MST radar. The detection techniques required on the ST radar for delineating meteor echo returns are described

A comparison of mercury burdens between St. Marks National Wildlife Refuge and St. Andrew Bay, Florida: Evaluation of fish body burdens and physiological responses in largemouth bass, spotted seatrout, striped mullet, and sunfish

Science.gov (United States)

Huge, D.H.; Rauschenberger, R.H.; Wieser, F.M.; Hemming, J.M.

2011-01-01

Musculature from the dorsal region of 130 largemouth bass (Micropterus salmoides), 140 sunfish (Lepomis sp.), 41 spotted seatrout (Cynoscion nebulosus) and 67 striped mullet (Mugil cephalus) were collected from five estuarine and five freshwater sites within the St. Marks National Wildlife Refuge and two estuarine and two freshwater sites from St. Andrew Bay, Florida, United States of America. Musculature was analyzed for total mercury content, sagittal otoliths were removed for age determination and physiological responses were measured. Largemouth bass and sunfish from the refuge had higher mercury concentrations in musculature than those from the bay. Male spotted seatrout, male striped mullet, male and female sunfish and female largemouth bass had mercury burdens positively correlated with length. The majority of all four species of fish from both study areas contained mercury levels below 1.5 part per million, the limit for safe consumption recommended the Florida Department of Health. In comparison, a significant percentage of largemouth bass and sunfish from several sampled sites, most notably Otter Lake and Lake Renfroe within St. Marks National Wildlife Refuge, had mercury levels consistent with the health department's guidelines of 'limited consumption' or 'no consumption guidelines.'

Estimating the returns to United Kingdom publicly funded musculoskeletal disease research in terms of net value of improved health outcomes.

Science.gov (United States)

Glover, Matthew; Montague, Erin; Pollitt, Alexandra; Guthrie, Susan; Hanney, Stephen; Buxton, Martin; Grant, Jonathan

2018-01-10

Building on an approach applied to cardiovascular and cancer research, we estimated the economic returns from United Kingdom public- and charitable-funded musculoskeletal disease (MSD) research that arise from the net value of the improved health outcomes in the United Kingdom. To calculate the economic returns from MSD-related research in the United Kingdom, we estimated (1) the public and charitable expenditure on MSD-related research in the United Kingdom between 1970 and 2013; (2) the net monetary benefit (NMB), derived from the health benefit in quality adjusted life years (QALYs) valued in monetary terms (using a base-case value of a QALY of £25,000) minus the cost of delivering that benefit, for a prioritised list of interventions from 1994 to 2013; (3) the proportion of NMB attributable to United Kingdom research; and (4) the elapsed time between research funding and health gain. The data collected from these four key elements were used to estimate the internal rate of return (IRR) from MSD-related research investments on health benefits. We analysed the uncertainties in the IRR estimate using a one-way sensitivity analysis. Expressed in 2013 prices, total expenditure on MSD-related research from 1970 to 2013 was £3.5 billion, and for the period used to estimate the rate of return, 1978-1997, was £1.4 billion. Over the period 1994-2013 the key interventions analysed produced 871,000 QALYs with a NMB of £16 billion, allowing for the net NHS costs resulting from them and valuing a QALY at £25,000. The proportion of benefit attributable to United Kingdom research was 30% and the elapsed time between funding and impact of MSD treatments was 16 years. Our best estimate of the IRR from MSD-related research was 7%, which is similar to the 9% for CVD and 10% for cancer research. Our estimate of the IRR from the net health gain to public and charitable funding of MSD-related research in the United Kingdom is substantial, and justifies the research investments

Stereospecificity (ST) of the microsomal ethanol oxidizing system (MEOS)

International Nuclear Information System (INIS)

Alderman, J.; Kato, S.; Lasker, J.; Lieber, C.S.

1987-01-01

The ST of MEOS for the ethanol 1R hydrogen has been variously reported as absolute, partial or absent, with free radical involvement postulated in the latter case. To determine both the ST of MEOS and the participation of free radicals in the reaction, they investigated MEOS ST using 1R[1- 3 H] ethanol as substrate. ST is expressed as the fraction of 3 H labeling in acetaldehyde formed, relative to that in ethanol, and ranges from 0.5 to 0. Partial ST was observed using liver microsomes from both rats and hamsters; it significantly decreased after ethanol feeding. 0.1 mM desferrioxamine (dfx) did not increase ST in any of these microsomal preparations while ferric EDTA decreased it, suggesting that ethanol treatment induces a cytochrome P-450 with lower ST rather than increasing free radical involvement. This is supported by a virtual absence of ST observed in a reconstituted system containing purified hamster P-450/sub ALC/, a liver cytochrome P-450 isozyme induced in hamsters by ethanol treatment. Their results indicate that, unlike other enzymes that oxidize ethanol, MEOS has only partial ST. Thus, ST alone cannot be used as an index of free radical involvement but, when evaluated with the response of ST to dfx, it indicated that MEOS is unlikely to involve free radical attack on ethanol in solution

Review of research on advanced computational science in FY2015

International Nuclear Information System (INIS)

2017-01-01

Research on advanced computational science for nuclear applications, based on 'Plan to Achieve Medium- to Long-term Objectives of the Japan Atomic Energy Agency (Medium- to Long-term Plan)', has been performed at Center for Computational Science and e-Systems (CCSE), Japan Atomic Energy Agency. CCSE established the committee consisting of outside experts and authorities which does research evaluation and advices for the assistance of the research and development. This report summarizes the followings. (1) Results of the R and D performed at CCSE in FY 2015 (April 1st, 2015 - March 31st, 2016), (2) Results of the evaluation on the R and D by the committee in FY 2015 (April 1st, 2015 - March 31st, 2016). (author)

Welcome to the 21st International Conference on Spectral Line Shapes

Science.gov (United States)

2012-12-01

Dear Participants and Guests On behalf of the Rector's Office, welcome to St. Petersburg University, one of the oldest, largest and most prestigious universities in Russia. The 12 Colleges Building (named after the Collegia of Peter the Great's time, Ministries in the modern sense of the word) has been home to the University since 1804. St. Petersburg State University is the successor of the first Russian University founded by Peter the Great on 24 January 1724. It's distinguished faculty members include mathematicians Chebyshev and Smirnov, physicists Lenz and Fock, chemists Mendeleev and Butlerov, embryologist Kovalevsky, and physiologist Sechenov. Several of our alumni won Nobel Prizes - Pavlov, Semenov, Kantorovich, Landau and Prokhorov. The University is the alma mater of two presidents of Russia, Vladimir Putin and Dmitry Medvedev. St. Petersburg State University today consists of 19 faculties on two campuses: in the historic downtown, on Vasilyevsky Island, and in Peterhof. The Faculty of Physics carries out research projects through the efforts of 260 employees, of which 150 hold doctoral degrees, and 50 have been awarded Grand Doctorates. The work is done in a vast variety of areas, from the physics of elementary particles to the physics of the atmosphere. Optics and spectroscopy has been a particularly significant area of research. This field of inquiry goes back to the work of Academician D S Rozhdestvensky more than 70 years ago, when he first suggested his famous hook method. After him the work was headed by S Frisch, corresponding member of the Academy of Sciences and editor-in-chief of Optics and Spectroscopy Journal. Today research projects in optics involve over 50 staff members, graduate and post-graduate students. Work involves projects on spectroscopy of cold and hot plasma, atomic and molecular spectroscopy, non-linear spectroscopy and spectroscopic analysis. Our scholars support active international ties with their colleagues worldwide. The

The Cerebral Palsy Research Registry: Development and Progress Toward National Collaboration in the United States

Science.gov (United States)

Hurley, Donna S.; Sukal-Moulton, Theresa; Msall, Michael E.; Gaebler-Spira, Deborah; Krosschell, Kristin J.; Dewald, Julius P.

2011-01-01

Cerebral palsy is the most common neurodevelopmental motor disability in children. The condition requires medical, educational, social, and rehabilitative resources throughout the life span. Several countries have developed population-based registries that serve the purpose of prospective longitudinal collection of etiologic, demographic, and functional severity. The United States has not created a comprehensive program to develop such a registry. Barriers have been large population size, poor interinstitution collaboration, and decentralized medical and social systems. The Cerebral Palsy Research Registry was created to fill the gap between population and clinical-based cerebral palsy registries and promote research in the field. This is accomplished by connecting persons with cerebral palsy, as well as their families, to a network of regional researchers. This article describes the development of an expandable cerebral palsy research registry, its current status, and the potential it has to affect families and persons with cerebral palsy in the United States and abroad. PMID:21677201

Japanese fusion research

International Nuclear Information System (INIS)

Uchida, T.

1987-01-01

The Japan experience during thirty years in nuclear fusion research is reported, after attending the 1st Geneva Conference in 1955, Osaka University, immedeately began linear pinch study using capacitor bank discharge. Subsequently to his trial several groups were organized to ward fusion R and D at universities in Tokyo, Nagoya, Kyoto, Sendai and son on. Based upon the recommendation of Japan Science Council, Institut of Plasma Physics (IPP) was established at Nagoya University in 1961 When the 1st International Conference on Plasma Physics and Controlled Nuclear Fusion Research was held in Saltzburg. The gloomy Bohm barrier had stood in front of many of experiments at that time. (author) [pt

Ghana Science Association. 21st biennial conference. Program and abstracts book

International Nuclear Information System (INIS)

1999-08-01

The publication covers the program and abstracts of papers presented during the 21st biennial conference of the Ghana Science Association. The conference was held at the University of Ghana, Legon from 8th to 13th August 1999. The theme of the conference was S ustainable food Industry in Ghana in the 21st Century . The first part of the publication covers membership of various committees, list of sponsors and conference program among others. The second part is devoted to abstracts of papers presented during various scientific sessions. Papers have been grouped under the following subject areas: Biological and Medical Science, Physical Sciences, Food and Agriculture, Social Science Education and Policy Research and Poster Presentations. (E.A.)

St. Fionnan's Community Nursing Unit, Achill Sound, Mayo.

LENUS (Irish Health Repository)

Murphy, JFA

2012-05-01

‘Jading’ is a process of exhaustion in which apathy and cynicism replace the drive to be responsive and caring. ‘Burnout’ a term first coined in the psychology literature in 1974 was based on Graham Greene’s novel ‘A Burnt-Out Case1. It is the umbrella description for disengagement in the workplace setting characterised by withdrawal, denial and inefficiency. There is an alienation from the pressures of work. Marshall and Kasman2 defined it as ‘the loss of motivation for creative thought’. It is the opposite of engagement which is associated with energy and optimism. People who experience all 3 symptoms- emotional exhaustion, negative attitude towards patients, reduced sense of personal accomplishment- have the greatest degree of burnout. It doesn’t get better by being ignored. These processes have serious consequences for the individual involved and the hospital that they work in. The doctor underperforms and the Unit becomes dysfunctional There is decreased quality of care, increased absenteeism, and high staff turnover. There is an inability to make decisions and a failure to set priorities.

Propaganda Art from the 20th to the 21st Century

NARCIS (Netherlands)

Staal, J.H.

2018-01-01

This study by artist Jonas Staal explores the development of propaganda art from the 20th to the 21st century. Staal defines propaganda as the performance of power by means of the equation propaganda = power + performance. Through his work as a propaganda researcher and practice as a

Reciprocal ST-Segment Changes in Myocardial Infarction: Ischemia at Distance Versus Mirror Reflection of ST-Elevation.

Science.gov (United States)

Vaidya, Gaurang Nandkishor; Antoine, Steve; Imam, Syed Haider; Kozman, Hani; Smulyan, Harold; Villarreal, Daniel

2018-02-01

Reciprocal ST-depression in the electrocardiograms (ECGs) of patients with ST-elevation myocardial infarction (STEMI) results from either true ischemia at a distance via collateral circulation diverting blood to the infarcted region or an electrical phenomenon that results from a mirror reflection of ST-elevation. We aimed to identify the role of reciprocal ECG changes in predicting collateral circulation to the infarcted area determined angiographically. In a retrospective study, ECG and angiography of 53 STEMI patients admitted to SUNY Upstate Medical University in 2014 were reviewed independently by experts blinded to the results of ECG and coronary angiography. Reciprocal changes (RC) in ECG were present in 41 patients (77%) and on angiography, 14 patients (26%) exhibited collateral vessels to the ischemic areas. No correlation was found between the presence of RC and collateral circulation (P = 0.384), or between the depth of reciprocal ST-depression and the degree of the collateral circulation (P = 0.195). However, 84% of patients without collaterals exhibited resolution of RC after successful percutaneous coronary intervention (PCI) (P = 0.036), suggesting that the ST depressions that resolved after reperfusion were directly caused by the culprit vessel. Patients without RC presented late after symptom onset (9.25 versus 3.83 hours, P = 0.004), also suggesting time related resolution. RC had no relation to or predictive value for collaterals on angiography. Among late presenting patients, RC were less frequent. Thus, reciprocal ST-depression may represent subendocardial ischemia from the primary coronary event or simply an electrical phenomenon, rather than ischemia at distance from impaired collateral circulation. Published by Elsevier Inc.

Firmaets Største Bedrift

DEFF Research Database (Denmark)

Hansen, Peer Henrik

fortæller, hvordan de tidligere modstandsfolk Arne Sejr og Niels Frommelt få år efter befrielsen etablerede deres såkaldte Firma for med støtte fra ledende danske politikere, Forsvarets Efterretningstjeneste og CIA at organisere en hemmelig krig mod Sovjetunionens danske støtter. Meget tyder på, at både...

Climate change influences on the annual onset of Lyme disease in the United States

Science.gov (United States)

Monaghan, A. J.; Moore, S. M.; Sampson, K. M.; Beard, C. B.; Eisen, R. J.

2015-12-01

Lyme disease is the most commonly reported vector-borne illness in the United States. Lyme disease occurrence is highly seasonal and the annual springtime onset of cases is modulated by meteorological conditions in preceding months. A meteorological-based empirical model for Lyme disease onset week in the United States is driven with downscaled simulations from five global climate models and four greenhouse gas emissions scenarios to project the impacts of 21st century climate change on the annual onset week of Lyme disease. Projections are made individually and collectively for the 12 eastern States where >90% of cases occur. The national average annual onset week of Lyme disease is projected to become 0.4-0.5 weeks earlier for 2025-2040 (pLyme disease spirochete Borrelia burgdorferi in the eastern United States, may alter the disease transmission cycle in unforeseen ways. The results suggest 21st century climate change will make environmental conditions suitable for earlier annual onset of Lyme disease cases in the United States with possible implications for the timing of public health interventions.

Escherichia coli ST131, an Intriguing Clonal Group

Science.gov (United States)

Bertrand, Xavier; Madec, Jean-Yves

2014-01-01

SUMMARY In 2008, a previously unknown Escherichia coli clonal group, sequence type 131 (ST131), was identified on three continents. Today, ST131 is the predominant E. coli lineage among extraintestinal pathogenic E. coli (ExPEC) isolates worldwide. Retrospective studies have suggested that it may originally have risen to prominence as early as 2003. Unlike other classical group B2 ExPEC isolates, ST131 isolates are commonly reported to produce extended-spectrum β-lactamases, such as CTX-M-15, and almost all are resistant to fluoroquinolones. Moreover, ST131 E. coli isolates are considered to be truly pathogenic, due to the spectrum of infections they cause in both community and hospital settings and the large number of virulence-associated genes they contain. ST131 isolates therefore seem to contradict the widely held view that high levels of antimicrobial resistance are necessarily associated with a fitness cost leading to a decrease in pathogenesis. Six years after the first description of E. coli ST131, this review outlines the principal traits of ST131 clonal group isolates, based on the growing body of published data, and highlights what is currently known and what we need to find out to provide public health authorities with better information to help combat ST131. PMID:24982321

Proposed plan for remedial action at the quarry residuals operable unit of the Weldon Spring Site

International Nuclear Information System (INIS)

1998-03-01

This proposed plan addresses the management of contamination present in various components of the quarry residuals operable unit (QROU) of the Weldon Spring site, which is located in St. Charles County, Missouri. The QROU consists of (1) residual waste at the quarry proper; (2) the Femme Osage Slough, Little Femme Osage Creek, and Femme Osage Creek; and (3) quarry groundwater located primarily north of the slough. Potential impacts to the St. Charles County well field downgradient of the quarry area are also being addressed as part of the evaluations for this operable unit. Remedial activities for the QROU will be conducted by the US Department of Energy (DOE) in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended. As part of the remedial investigation/feasibility study (RI/FS) process required for the QROU under CERCLA, three major evaluation documents have been prepared to support cleanup decisions for this operable unit. decisions for this operable unit

Estudo comparativo de flores casmógamas, cleistógamas e de frutos de Camarea affinis St.-Hil. (Malpighiaceae Comparative study of casmogamous and cleistogamous flowers and Camarea affinis St.-Hil. fruits (Malpighiaceae

Directory of Open Access Journals (Sweden)

Maria Candida Henrique Mamede

1993-07-01

Full Text Available O gênero Camarea pertence a tribo Gaudichaudieae caracterizada pela redução no número de elementos do androceu, gineceu parcialmente sincárpico, estilete único e ginobásico e pela ocorrência de flores cleistógamas. Neste trabalho é feito o estudo de Camarea affinis St-Hil. no que se refere à morfologia e á anatomia de flores casmógamas e cleistógamas, assim como de seus respectivos frutos.The genus Camarea belongs to the tribe Gaudichaudieae, which is traditionally characterized by a solitaiy gynobasic style, presence of veiy reduced cleistogamous flowers, an androecium of 6 staminal elements and carpels only partially united. This paper presents information about the morphology and the anatomy of chamosgamous and cleistogamous flowers and fruits of Camarea affinis St HiL

Role of myocardial ischemia on exercise-induced ST elevation

International Nuclear Information System (INIS)

Saito, Muneyasu; Sumiyoshi, Tetsuya; Nishimura, Tsunehiko; Uehara, Toshiisa; Hayashida, Kouhei; Haze, Kazuo; Fukami, Ken-ichi; Hiramori, Katsuhiko

1986-01-01

Exercise-induced ST elevation in patients with previous myocardial infarction (MI) has been recognized to be related to left ventricular (LV) asynergy, however it is also recognized that myocardial ischemia can induce ST elevation. In this study, factors which determine the extent of ST elevation, with special reference to myocardial ischemia, was re-evaluated using quantitative analysis of stress myocardial scintigraphy (S-SG). Among 65 patients with previous anterior myocardial infarction and documented single vessel disease of left anterior descending artery (LAD), 19 patients who had exercise-induced ST elevation (ΔST ≥ 2.0 mm) had more abnormal Q waves (p < 0.01), lower LV ejection fraction (EF) (p < 0.01), more severe LV asynergy (p < 0.05) and less incidence of post-MI angina pectoris (AP) (p < 0.01), compared to those with ΔST < 2.0 mm, indicating that ST elevation is primarily related to LV asynergy. Correlation studies among clinical, angiographic and scintigraphic parameters show that ΔST was significantly related to a size of MI represented by Tl score or relative defect Tl activity and number of abnormal Q waves (No.Q), the magnitude of work load expressed by changes in double product (ΔDP) and intervals between the onset and exercise test, as well as myocardial ischemia expressed by the extent of redistribution (%RD) in S-SG. Among 23 patients with post-MI AP, ΔST significantly correlated with %RD (r = 0.47), indicating that myocardial ischemia can be a mechanism of exercise-induced ST elevation in patients with previous MI. Furtheremore, among those with ST elevation, concave-type ST elevation was more related to myocardial ischemia compared to convex-type ST elevation as expressed by the incidence of post-MI AP and/or significant redistribution. (J.P.N.)

Current nondestructive evaluation research and development trends in the United States

International Nuclear Information System (INIS)

Jackson, Jerry

1992-01-01

An underlying theme present in much of the nondestructive evaluation (NDE) research and development occurring in the United States as well as worldwide is the application of physics and engineering principles toward understanding and optimizing NDE processes. Expanding this trend of using mathematical models for NDE processes is critical to the entire spectrum of NDE technology. In NDE research, modeling anchors the investigation in scientific, proven principles and establishes a firm technical basis to guide the design and development of inspection equipment and approaches. It also provides for understanding the capabilities and the limitations of whatever designs are selected and ultimately applied in the field. This paper reviews the status of these efforts, presents several examples where mathematical modeling is being profitably used for practical inspection work, and shows the path being taken in ongoing research.

Molecular Characterization of Methicillin Resistant Staphylococcus aureus Strains Isolated from Intensive Care Units in Iran: ST22-SCCmec IV/t790 Emerges as the Major Clone.

Science.gov (United States)

Goudarzi, Mehdi; Goudarzi, Hossein; Sá Figueiredo, Agnes Marie; Udo, Edet E; Fazeli, Maryam; Asadzadeh, Mohammad; Seyedjavadi, Sima Sadat

2016-01-01

The emergence of methicillin-resistant Staphylococcus aureus (MRSA) in different patient populations is a major public health concern. This study determined the prevalence and distribution of circulating molecular types of MRSA in hospitalized patients in ICU of hospitals in Tehran. A total of 70 MRSA isolates were collected from patients in eight hospitals. Antimicrobial resistance patterns were determined using the disk diffusion method. The presence of toxin encoding genes and the vancomycin resistance gene were determined by PCR. The MRSA isolates were further analyzed using multi-locus sequence, spa, SCCmec, and agr typing. The MRSA prevalence was 93.3%. Antimicrobial susceptibility testing revealed a high resistance rate (97.1%) to ampicillin and penicillin. The rate of resistance to the majority of antibiotics tested was 30% to 71.4%. Two isolates belonging to the ST22-SCCmec IV/t790 clone (MIC ≥ 8 μg/ml) had intermediate resistance to vancomycin. The majority of MRSA isolates (24.3%) were associated with the ST22-SCCmec IV/t790 clone; the other MRSA clones were ST859-SCCmec IV/t969 (18.6%), ST239-SCCmec III/t037 (17.1%), and ST291-SCCmec IV/t030 (8.6%). The circulating MRSA strains in Iranian hospitals were genetically diverse with a relatively high prevalence of the ST22-SCCmec IV/t790 clone. These findings support the need for future surveillance studies on MRSA to better elucidate the distribution of existing MRSA clones and detect emergence of new MRSA clones.

Identification of a novel clone, ST736, among Enterococcus faecium clinical isolates and its association with daptomycin nonsusceptibility.

Science.gov (United States)

Wang, Guiqing; Kamalakaran, Sitharthan; Dhand, Abhay; Huang, Weihua; Ojaimi, Caroline; Zhuge, Jian; Yee, Leslie Lee; Mayigowda, Pramod; Surendraiah, Pavan Kumar Makam; Dimitrova, Nevenka; Fallon, John T

2014-08-01

Resistance to daptomycin in enterococcal clinical isolates remains rare but is being increasingly reported in the United States and worldwide. There are limited data on the genetic relatedness and microbiological and clinical characteristics of daptomycin-nonsusceptible enterococcal clinical isolates. In this study, we assessed the population genetics of daptomycin-nonsusceptible Enterococcus faecium (DNSE) clinical isolates by multilocus sequence typing (MLST) and whole-genome sequencing analysis. Forty-two nonduplicate DNSE isolates and 43 randomly selected daptomycin-susceptible E. faecium isolates were included in the analysis. All E. faecium isolates were recovered from patients at a tertiary care medical center in suburban New York City from May 2009 through December 2013. The daptomycin MICs of the DNSE isolates ranged from 6 to >256 μg/ml. Three major clones of E. faecium (ST18, ST412, and ST736) were identified among these clinical isolates by MLST and whole-genome sequence-based analysis. A newly recognized clone, ST736, was seen in 32 of 42 (76.2%) DNSE isolates and in only 14 of 43 (32.6%) daptomycin-susceptible E. faecium isolates (P clone ST736 and daptomycin nonsusceptibility. The identification and potential spread of this novel E. faecium clone and its association with daptomycin nonsusceptibility constitute a challenge for patient management and infection control at our medical center. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Connecting Arctic Research Across Boundaries through the Arctic Research Consortium of the United States (ARCUS)

Science.gov (United States)

Rich, R. H.; Myers, B.; Wiggins, H. V.; Zolkos, J.

2017-12-01

The complexities inherent in Arctic research demand a unique focus on making connections across the boundaries of discipline, institution, sector, geography, knowledge system, and culture. Since 1988, ARCUS has been working to bridge these gaps through communication, coordination, and collaboration. Recently, we have worked with partners to create a synthesis of the Arctic system, to explore the connectivity across the Arctic research community and how to strengthen it, to enable the community to have an effective voice in research funding policy, to implement a system for Arctic research community knowledge management, to bridge between global Sea Ice Prediction Network researchers and the science needs of coastal Alaska communities through the Sea Ice for Walrus Outlook, to strengthen ties between Polar researchers and educators, and to provide essential intangible infrastructure that enables cost-effective and productive research across boundaries. Employing expertise in managing for collaboration and interdisciplinarity, ARCUS complements and enables the work of its members, who constitute the Arctic research community and its key stakeholders. As a member-driven organization, everything that ARCUS does is achieved through partnership, with strong volunteer leadership of each activity. Key organizational partners in the United States include the U.S. Arctic Research Commission, Interagency Arctic Research Policy Committee, National Academy of Sciences Polar Research Board, and the North Slope Science Initiative. Internationally, ARCUS maintains strong bilateral connections with similarly focused groups in each Arctic country (and those interested in the Arctic), as well as with multinational organizations including the International Arctic Science Committee, the Association of Polar Early Career Educators, the University of the Arctic, and the Arctic Institute of North America. Currently, ARCUS is applying the best practices of the science of team science

Prevalence of Risk Factors for the Metabolic Syndrome in the Middle Income Caribbean Nation of St. Lucia

Science.gov (United States)

Cherry, Colleen O'Brien; Serieux, Elizabeth; Didier, Martin; Nuttal, Mary Elizabeth; Schuster, Richard J.

2014-01-01

The objective of this research was to measure the presence of metabolic syndrome risk factors in a sample population in the middle income Caribbean nation of St. Lucia and to identify the demographic and behavioral factors of metabolic syndrome among the study participants. Interviews and anthropometric measures were conducted with 499 St. Lucians of ages 18–99. Descriptive statistics were used for the analysis. Fifty-six percent of females and 18 percent of males had a waist size equal to or above the indicator for the metabolic syndrome. Behavioral risk factors such as sedentary lifestyle, smoking, and alcohol consumption varied by gender. Thirty-six percent of women and 22% of men reported a sedentary lifestyle and 43% of women and 65% of men reported any alcohol consumption. More research should be done to determine the cultural norms and gender differences associated with modifiable risk behaviors in St. Lucia. PMID:25309758

Fiscal 1999 research report. Basic research for promotion of joint implementation programs (Scrap and build for Central Heat-Power Station No. 2, St. Petersburg City, and others); 1999 nendo St. Petersburg shi netsuden heikyusho No.2 hoka Scrap and Build chosa hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-03-01

Japan intends to resort to various means, including joint implementations with advanced countries, to fulfill its greenhouse gas reduction target in compliance with the United Nations Framework Convention on Climate Change. Exerting one of Japan's efforts, Mitsui and Co., Ltd., has signed a protocol with LENENEGRO on a survey of the Central Heat-Power Station, St. Petersburg City. The heat-power station started its operation in the 1910s and is now quite superannuated. Its efficiency and operating rate have extremely lowered, and its early modernization is earnestly wished for. The aim of the survey is to have the existing old facilities scrapped for the installation of gas combined cycle cogeneration facilities which are high in efficiency and low in greenhouse gas emissions. The new facilities will consist of three 67MW-class gas turbines, three exhaust heat recovery boilers, and one backpressure turbine, capable of 200MW power generation and 200Gcal/hour heat supply. A total of 140-million dollars will have to be invested and the construction work will require 36 months to complete. A reduction of 1,481,979.0 tons/year in CO2 emissions and an energy saving effect of 546,301 tons/year are expected. (NEDO)

Management of dental unit waterline biofilms in the 21st century.

LENUS (Irish Health Repository)

O'Donnell, Mary J

2011-10-01

Dental chair units (DCUs) use water to cool and irrigate DCU-supplied instruments and tooth surfaces, and provide rinsewater during dental treatment. A complex network of interconnected plastic dental unit waterlines (DUWLs) supply water to these instruments. DUWLs are universally prone to microbial biofilm contamination seeded predominantly from microorganisms in supply water. Consequently, DUWL output water invariably becomes contaminated by high densities of microorganisms, principally Gram-negative environmental bacteria including Pseudomonas aeruginosa and Legionella species, but sometimes contain human-derived pathogens such as Staphylococcus aureus. Patients and staff are exposed to microorganisms from DUWL output water and to contaminated aerosols generated by DCU instruments. A wide variety of approaches, many unsuccessful, have been proposed to control DUWL biofilm. More recently, advances in biofilm science, chemical DUWL biofilm treatment agents, DCU design, supply water treatment and development of automated DUWL biofilm control systems have provided effective long-term solutions to DUWL biofilm control.

21st International Meshing Roundtable

CERN Document Server

Weill, Jean-Christophe

2013-01-01

This volume contains the articles presented at the 21st International Meshing Roundtable (IMR) organized, in part, by Sandia National Laboratories and was held on October 7–10, 2012 in San Jose, CA, USA. The first IMR was held in 1992, and the conference series has been held annually since. Each year the IMR brings together researchers, developers, and application experts in a variety of disciplines, from all over the world, to present and discuss ideas on mesh generation and related topics. The technical papers in this volume present theoretical and novel ideas and algorithms with practical potential, as well as technical applications in science and engineering, geometric modeling, computer graphics, and visualization.

1st European Conference on Gas Micro Flows (GasMems 2012)

NARCIS (Netherlands)

Frijns, A.J.H.; Valougeorgis, D.; Colin, S.; Baldas, L.

2012-01-01

PREFACE The aim of the 1st European Conference on Gas Micro Flows is to advance research in Europe and worldwide in the field of gas micro flows as well as to improve global fundamental knowledge and to enable technological applications. Gas flows in microsystems are of great importance and touch

Exploring the SCOAP3 Research Contributions of the United States

Science.gov (United States)

Marsteller, Matthew

2016-03-01

The Sponsoring Consortium for Open Access Publishing in Particle Physics (SCOAP3) is a successful global partnership of libraries, funding agencies and research centers. This presentation will inform the audience about SCOAP3 and also delve into descriptive statistics of the United States' intellectual contribution to particle physics via these open access journals. Exploration of the SCOAP3 particle physics literature using a variety of metrics tools such as Web of Science™, InCites™, Scopus® and SciVal will be shared. ORA or Sci2 will be used to visualize author collaboration networks.

Structure and petroleum plays of the St. Lawrence Platform and Appalachians in southern Quebec : insights from interpretation of MRNQ seismic reflection data

Energy Technology Data Exchange (ETDEWEB)

Castonguay, S.; Lavoie, D. [Natural Resources Canada, Quebec, PQ (Canada). Geological Survey of Canada, Quebec Division; Dietrich, J. [Natural Resources Canada, Calgary, AB (Canada). Geological Survey of Canada; Laliberte, J.Y. [Ministere des Ressources naturelles et de la Faune du Quebec, Charlesbourg, QC (Canada). Direction generale des hydrocarbures et des biocarburants

2010-09-15

This paper presented the results of a study in which 3 regional seismic reflection lines originally acquired in 1978 were reprocessed and reinterpreted using current techniques and methodologies. The profiles cross the Chambly-Fortierville syncline and provide images of the St. Lawrence Platform and the Appalachian foreland thrust belt of southern Quebec, including one that spans the entire width of the southern Quebec Appalachians. Post-stack seismic data processing and time migration were used to improve the quality of the original seismic sections, allowing interpretations that provide new information on subsurface geology, such as the recognition of complex structural patterns in platform and foreland units, the presence of a triangle zone at the structural front, and the geometry of thrust slices of platform units and Appalachian thrust beds, as well as images of the internal Humber Zone, including back-thrust faults and mega thrust wedges. The Saint-Flavien natural gas-field and other potential targets in the St. Lawrence Platform and Appalachian Foreland are imaged in the seismic profiles. The study provided new insights into the structure, geological evolution, and petroleum potential of the St. Lawrence Platform and the Appalachian foreland thrust belt of southern Quebec, including a potential, previously unrecognized Ordovician hydrothermal dolomite play. The new subsurface interpretations give a clearer view of the major structure affecting the Utica Shale, providing new insights into the limits of the unconventional shale gas play in the St. Lawrence Platform. 53 refs., 8 figs.

Globalisation, Language and Education: A Comparative Study of the United States and Tanzania

Science.gov (United States)

Roy-Campbell, Zaline M.

2001-07-01

Educational language choice has been one of the most provocative issues of the 20th century and continues to be a dominant issue at the turn of the new millennium. Efforts to naturalize English as the only suitable language for post primary school education persist in many African countries, including Tanzania. In the United States the campaign for "English only" in the schools is gaining momentum, despite the increasing multilingual population in the schools. Focusing on Tanzania and the United States, this article examines the fallacy of a monolingual, English only, policy in education. It examines the ethos surrounding the debate about the language of instruction, and considers some of the detrimental effects upon students of attempting to impose a monolingual policy. Finally, the paper suggests possible roles of educators and researchers in fostering international understanding of educational language issues as one aspect of the quest for global peace and social justice in the 21st century.

Federal laboratories for the 21st century

Energy Technology Data Exchange (ETDEWEB)

Gover, J. [Sandia National Labs., Albuquerque, NM (United States); Huray, P.G. [Univ. of South Carolina, Columbia, SC (United States)

1998-04-01

Federal laboratories have successfully filled many roles for the public; however, as the 21st Century nears it is time to rethink and reevaluate how Federal laboratories can better support the public and identify new roles for this class of publicly-owned institutions. The productivity of the Federal laboratory system can be increased by making use of public outcome metrics, by benchmarking laboratories, by deploying innovative new governance models, by partnerships of Federal laboratories with universities and companies, and by accelerating the transition of federal laboratories and the agencies that own them into learning organizations. The authors must learn how government-owned laboratories in other countries serve their public. Taiwan`s government laboratory, Industrial Technology Research Institute, has been particularly successful in promoting economic growth. It is time to stop operating Federal laboratories as monopoly institutions; therefore, competition between Federal laboratories must be promoted. Additionally, Federal laboratories capable of addressing emerging 21st century public problems must be identified and given the challenge of serving the public in innovative new ways. Increased investment in case studies of particular programs at Federal laboratories and research on the public utility of a system of Federal laboratories could lead to increased productivity of laboratories. Elimination of risk-averse Federal laboratory and agency bureaucracies would also have dramatic impact on the productivity of the Federal laboratory system. Appropriately used, the US Federal laboratory system offers the US an innovative advantage over other nations.

Education and Job Training: Preparing for the 21st Century Workforce. Hearing before the Subcommittee on 21st Century Competitiveness of the Committee on Education and the Workforce, House of Representatives. One Hundred Seventh Congress, Second Session (Angola, Indiana, March 22, 2002).

Science.gov (United States)

Congress of the U.S., Washington, DC. House Committee on Education and the Workforce.

This is a congressional hearing on how vocational and technical education and job training work together to better prepare workers for the 21st century workforce and on successful educational and job training activities and initiatives in Indiana (IN). Testimony includes statements from United States representatives (Howard P. "Buck"…

Isolation and characterization of StERF transcription factor genes from potato (Solanum tuberosum L.).

Science.gov (United States)

Wang, Zemin; Zhang, Ning; Zhou, Xiangyan; Fan, Qiang; Si, Huaijun; Wang, Di

2015-04-01

Ethylene response factor (ERF) is a major subfamily of the AP2/ERF family and plays significant roles in the regulation of abiotic- and biotic-stress responses. ERF proteins can interact with the GCC-box cis-element and then initiate a transcriptional cascade activating downstream ethylene response and enhancing plant stress tolerance. In this research, we cloned five StERF genes from potato (Solanum tuberosum L.). The expressional analysis of StERF genes revealed that they showed tissue- or organ-specific expression patterns and the expression levels in leaf, stem, root, flower, and tuber were different. The assays of quantitative real-time polymerase chain reaction (qRT-PCR) and the reverse transcription-PCR (RT-PCR) showed that the expression of five StERF genes was regulated by ethephon, methyl jasmonate (MeJA), salt and drought stress. The result from the yeast one-hybrid experiment showed that five StERFs had trans-activation activity and could specifically bind to the GCC-box cis-elements. The StERFs responded to abiotic factors and hormones suggested that they possibly had diverse roles in stress and hormone regulation of potato. Copyright © 2015 Académie des sciences. Published by Elsevier SAS. All rights reserved.

Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4

DEFF Research Database (Denmark)

Mereiter, Stefan; Magalhães, Ana; Adamczyk, Barbara

2016-01-01

Gastric carcinoma MKN45 cells stably transfected with the full-length ST3GAL4 gene were characterised by glycomic and sialoproteomic analysis. Complementary strategies were applied to assess the glycomic alterations induced by ST3GAL4 overexpression. The N- and O-glycome data were generated in two......-MS/MS identification was performed. This analysis identified 47 proteins with significantly increased sialylation. The data in this article is associated with the research article published in Biochim Biophys Acta "Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine...... kinase activation in cancer" [1]....

FY 1998 Blue Book: Computing, Information, and Communications: Technologies for the 21st Century

Data.gov (United States)

Networking and Information Technology Research and Development, Executive Office of the President — As the 21st century approaches, the rapid convergence of computing, communications, and information technology promises unprecedented opportunities for scientific...

ST Elevation in aVR with Coexistent Multilead ST Depression

Directory of Open Access Journals (Sweden)

Benjamin Cooper

2017-01-01

Full Text Available History of present illness: An 80-year-old female with a history of Crohn’s disease presented to the emergency department with chest pain. She had two weeks of exertional chest pain that preceded an episode of chest pain immediately prior to arrival associated with diaphoresis. Her pain nearly completely resolved with sublingual nitroglycerin provided by pre-hospital personnel. She was hemodynamically stable with normal vital signs on arrival. An ECG was immediately obtained. Significant findings: The ECG shows ST-segment depressions in precordial leads V3 through V6, and limb leads I, II, and aVL, and 1 mm of ST-segment elevation in aVR. The initial troponin I was elevated at 1.37 ng/mL (upper limit of normal 0.40. Cardiology decided to delay catheterization until the next day when diffuse coronary disease was discovered (including 90% of the left circumflex stenosis, 60% proximal and 75% mid-left anterior descending stenosis, 75% third diagonal branch stenosis, and 90% posterior descending artery stenosis. The following day, the patient went to the operating room for coronary artery bypass grafting (CABG. Discussion: Traditionally, lead aVR has not received attention when interpreting acutely ischemic changes on ECG, leading some to refer to it as “the forgotten lead.”1 Current guidelines acknowledge the significance of multilead ST depression with coexistent ST elevation in aVR, and this pattern has been identified as the strongest predictor of severe left main coronary artery and/or 3-vessel disease (LM/3VD.2-3 When this ECG pattern is recognized in patients with ischemic symptoms, the emergency physician should involve cardiology early. When managing patients with suspected LM/3VD, it is important to withhold dual anti-platelet therapy as CABG is likely to be indicated,1,3 and guidelines recommend discontinuing P2Y12 inhibitors like clopidogrel or ticagrelor at least 24 hours prior to urgent CABG.2

[The attempts at drug therapy of cancer by Anton Störck (1731-1803). History of experimental pharmacology in the old Vienna Medical School].

Science.gov (United States)

Schweppe, K W; Probst, C

1982-03-15

The essay deals with the development of medical research in Vienna - especially the development of therapeutic drugs. This progress is related to the philosophical, historical, and political background of the enlightened absolutism and the reformatory efforts of van Swieten during the regency of Maria Theresia in Austria. Anton Störck's research on hemlock (Conium maculatum) is used as an example. The method of Störck's research-work is described. Furthermore it is demonstrated to what extent Störck's data, deduced from empirical examinations, are integrated in the official medical system, i.e. Boerhaave's iatromechanic system. Finally the attempt is made to correlate these processes of medical history with the scientific-historical model of Thomas Kuhn.

The cognitive status of stød

DEFF Research Database (Denmark)

Clausen, Sara Juul; Kristensen, Line Burholt

2015-01-01

marked. Keeping in mind the cross-distribution between phonetic/phonological markedness and distributional patterns, we investigate here whether stød is also related to accent 1 when it comes to cognitive markedness. We present the results of a psycholinguistic study in which participants attended...... for words with non-stød stems, indicating that the cognitive markedness status of stød corresponds to that of accent 2....

The United States Culture Collection Network (USCCN): Enhancing Microbial Genomics Research through Living Microbe Culture Collections

Science.gov (United States)

Boundy-Mills, Kyria; Hess, Matthias; Bennett, A. Rick; Ryan, Matthew; Kang, Seogchan; Nobles, David; Eisen, Jonathan A.; Inderbitzin, Patrik; Sitepu, Irnayuli R.; Torok, Tamas; Brown, Daniel R.; Cho, Juliana; Wertz, John E.; Mukherjee, Supratim; Cady, Sherry L.

2015-01-01

The mission of the United States Culture Collection Network (USCCN; http://usccn.org) is “to facilitate the safe and responsible utilization of microbial resources for research, education, industry, medicine, and agriculture for the betterment of human kind.” Microbial culture collections are a key component of life science research, biotechnology, and emerging global biobased economies. Representatives and users of several microbial culture collections from the United States and Europe gathered at the University of California, Davis, to discuss how collections of microorganisms can better serve users and stakeholders and to showcase existing resources available in public culture collections. PMID:26092453

Proceedings of Symposium on Energy Engineering in the 21st Century (SEE 2000). Volume Three

Science.gov (United States)

2000-01-13

osmotic agents for dehydration of vegetables and fruits are table salt, sucrose, glucose , fructose , starch, corn syrup , glycerol, and plant...Technology Clear Water Bay, Kowloon, Hong Kong Begell House New York, Wallingford (U.K.) DISTRIBUTION STATEMENT A Approved for Public Release...TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Hong Kong University of S&T Clear Water Bay Hong Kong Hong

31st IMAC Conference on Structural Dynamics

CERN Document Server

Adams, Douglas; Carrella, Alex; Mayes, Randy; Rixen, Daniel; Allen, Matt; Cunha, Alvaro; Catbas, Fikret; Pakzad, Shamim; Racic, Vitomir; Pavic, Aleksandar; Reynolds, Paul; Simmermacher, Todd; Cogan, Scott; Moaveni, Babak; Papadimitriou, Costas; Allemang, Randall; Clerck, James; Niezrecki, Christopher; Wicks, Alfred

2013-01-01

Topics in Nonlinear Dynamics, Volume 1: Proceedings of the 31st IMAC, A Conference and Exposition on Structural Dynamics, 2013, the first volume of seven from the Conference, brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on fundamental and applied aspects of Structural Dynamics, including papers on:   Nonlinear Oscillations Nonlinearities In Practice Nonlinear System Identification: Methods Nonlinear System Identification: Friction & Contact Nonlinear Modal Analysis Nonlinear Modeling & Simulation Nonlinear Vibration Absorbers Constructive Utilization of Nonlinearity.

Effect of St.John's wort (Hypericum perforatum) oily extract for the care and treatment of pressure sores; a case report.

Science.gov (United States)

Yücel, Ali; Kan, Yüksel; Yesilada, Erdem; Akın, Onat

2017-01-20

Topical formulations such as oily extracts or ointments prepared with the flowering aerial parts of St. John's wort (Hypericum perforatum L., Hypericaceae) have been used in the management of a wide range dermatological problems including superficial wounds and burns, bruises, contusions and many others in the worldwide traditional medicines. This is the first case study reporting the beneficial effects of an oily extract of St. John's wort in the treatment of pressure sores in a intensive care unit (ICU) patient. The oily extract of St. John's wort was applied to a volunteer patient at ICU daily for forty successive days for wound care and treatment. Healing status was monitored macroscopically by measuring the wound size and stages at certain intervals as well as histopathological evaluation of the tissue sections taken at the initial and final dates of treatment. Evaluation of the results obtained from the macroscopical and histopathological experimentation have shown that oily extract of St. John's wort provided significant efficacy for the treatment of pressure sore wounds. St. John's wort oily extract may be suggested as a cost-effective option for the prevention or treatment of pressure sores in ICU patients. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Spot Støjbergs støj

DEFF Research Database (Denmark)

Kock, Christian Erik J

2015-01-01

Inger Støjberg er placeret på en af de mest profilerede poster i Løkkes regering. Spørger du hende om fortiden, taler hun om fremtiden. Spørger du hende om fremtiden, taler hun om fortiden. Ergo: Hun taler udenom, og hun er god til det. Hun er så god, at det skader demokratiet. Lær at spotte hend...

Characteristics of potential repository wastes: Volume 4, Appendix 4A, Nuclear reactors at educational institutions of the United States; Appendix 4B, Data sheets for nuclear reactors at educational institutions; Appendix 4C, Supplemental data for Fort St. Vrain spent fuel; Appendix 4D, Supplemental data for Peach Bottom 1 spent fuel; Appendix 4E, Supplemental data for Fast Flux Test Facility

International Nuclear Information System (INIS)

1992-07-01

Volume 4 contains the following appendices: nuclear reactors at educational institutions in the United States; data sheets for nuclear reactors at educational institutions in the United States(operational reactors and shut-down reactors); supplemental data for Fort St. Vrain spent fuel; supplemental data for Peach Bottom 1 spent fuel; and supplemental data for Fast Flux Test Facility

Clonal emergence of Klebsiella pneumoniae ST14 co-producing OXA-48-type and NDM carbapenemases with high rate of colistin resistance in Dubai, United Arab Emirates.

Science.gov (United States)

Moubareck, Carole Ayoub; Mouftah, Shaimaa F; Pál, Tibor; Ghazawi, Akela; Halat, Dalal H; Nabi, Anju; AlSharhan, Mouza A; AlDeesi, Zulfa O; Peters, Christabel C; Celiloglu, Handan; Sannegowda, Manjunath; Sarkis, Dolla K; Sonnevend, Ágnes

2018-03-09

Few studies have addressed the molecular epidemiology of carbapenem resistant Enterobacteriaceae (CRE) isolates in the Arabian Peninsula, and such investigations have been missing from Dubai, a major economical, tourism and medical centre of the region. The antibiotic susceptibility, the carbapenemase type produced, and the clonality of 89 CRE strains isolated in five major Dubai hospitals in June 2015 - June 2016 were determined. Thirty three percent of the collection of 70 K. pneumoniae, 13 E. coli and 6 other Enterobacteriaceae were extremely drug resistant, 27% were resistant to colistin, and 4.5% (four K. pneumoniae isolates) were resistant to all antibiotics tested. The colistin resistance rate in K. pneumoniae was 31.4%. None of the isolates carried mobile colistin resistance genes. Seventy-seven isolates produced carbapenemase: 53.3% OXA-48-like, 24.7% NDM, and 22.1% both OXA-48-like and NDM, respectively. PFGE clustered 50% of K. pneumoniae into a 35-membered group, which showed significant association with double carbapenemase production, with extreme drug resistance, and with being isolated from Emirati patients. Members of the cluster belonged to sequence type ST14. The rate of colistin resistance in K. pneumoniae ST14 was 37.1% vs. 27.1% of K. pneumoniae isolates outside of the cluster. Two of the panresistant K. pneumoniae isolates also belonged to ST14, whereas the other two were ST15 and ST231, respectively. In conclusion, beyond the overall high colistin resistance rate in CRE, the emergence of a highly resistant clone of K. pneumoniae ST14 in all Dubai hospitals investigated is a serious problem requiring immediate attention. Copyright © 2018. Published by Elsevier B.V.

The neural crest migrating into the 21st century

Science.gov (United States)

Bronner, Marianne E.; Simões-Costa, Marcos

2016-01-01

From the initial discovery of the neural crest over 150 years ago to the seminal studies of Le Douarin and colleagues in the latter part of the 20th century, understanding of the neural crest has moved from the descriptive to the experimental. Now, in the 21st century, neural crest research has migrated into the genomic age. Here we reflect upon the major advances in neural crest biology and the open questions that will continue to make research on this incredible vertebrate cell type an important subject in developmental biology for the century to come. PMID:26970616

Review of research on advanced computational science in FY2010-2014

International Nuclear Information System (INIS)

2016-03-01

Research on advanced computational science for nuclear applications, based on 'the plan for meeting the mid-term goal of the Japan Atomic Energy Agency', has been performed at Center for Computational Science and e-Systems (CCSE), Japan Atomic Energy Agency. CCSE established the committee consisting outside experts and authorities which does research evaluation and advices for the assistance of the research and development. This report summarizes the followings. (1) Results of the R and D performed at CCSE in the period of the midterm plan (April 1st, 2010 - March 31st, 2015) (2) Results of the evaluation on the R and D by the committee in the period of the midterm plan (April 1st, 2010 - March 31st, 2015). (author)

VaST: A variability search toolkit

Science.gov (United States)

Sokolovsky, K. V.; Lebedev, A. A.

2018-01-01

Variability Search Toolkit (VaST) is a software package designed to find variable objects in a series of sky images. It can be run from a script or interactively using its graphical interface. VaST relies on source list matching as opposed to image subtraction. SExtractor is used to generate source lists and perform aperture or PSF-fitting photometry (with PSFEx). Variability indices that characterize scatter and smoothness of a lightcurve are computed for all objects. Candidate variables are identified as objects having high variability index values compared to other objects of similar brightness. The two distinguishing features of VaST are its ability to perform accurate aperture photometry of images obtained with non-linear detectors and handle complex image distortions. The software has been successfully applied to images obtained with telescopes ranging from 0.08 to 2.5 m in diameter equipped with a variety of detectors including CCD, CMOS, MIC and photographic plates. About 1800 variable stars have been discovered with VaST. It is used as a transient detection engine in the New Milky Way (NMW) nova patrol. The code is written in C and can be easily compiled on the majority of UNIX-like systems. VaST is free software available at http://scan.sai.msu.ru/vast/.

The 21st Century Cures Act: pharmacoeconomic boon or bane?

Science.gov (United States)

Mendoza, Roger Lee

2017-04-01

Barriers to entry in healthcare markets constitute one of the overriding concerns of health economists. The recent enactment of the 21st Century Cures Act in the United States reduces statutory entry barriers to the discovery, development, testing, and licensing of drugs and medical devices. Drug and device makers also see the burdensome and time-consuming requirements of the Food and Drug Administration?s approval process as key barriers to lowering the costs of their products, considering it takes a decade of research amounting to $1 billion just to bring a single drug to the market. Along with novel opportunities for medical product innovation and faster treatment of diseases, the expedited approval process carries with it contentious challenges involving the safety, efficacy and value of drugs and devices. The ensuing trade-offs and unintended consequences of such a regulatory game-changer bring to the fore one of the most enduring debates between medicine and economics: Whether - or to what extent - cost and efficiency factors affect clinical inquiry into possible solutions to human illnesses. The practical and theoretical contributions of pharmacoeconomics should enlighten contemporary and future issues and discussions surrounding the implementation of this landmark legislation. After all, despite its undeniably good intent and far-reaching significance, no law can ever be perfect.

21st September 2010 - Representatives of the German Federal Ministry of eEducation and Research accompanied by M. Hauschield, ATLAS Collaboration, visiting the LHC superconducting magnet test hall with Department Head F. Bordry and R. Schmidt.

CERN Multimedia

Maximilien Brice

2010-01-01

21st September 2010 - Representatives of the German Federal Ministry of eEducation and Research accompanied by M. Hauschield, ATLAS Collaboration, visiting the LHC superconducting magnet test hall with Department Head F. Bordry and R. Schmidt.

Chicago-St. Louis high speed rail plan

International Nuclear Information System (INIS)

Stead, M.E.

1994-01-01

The Illinois Department of Transportation (IDOT), in cooperation with Amtrak, undertook the Chicago-St. Louis High Speed Rail Financial and Implementation Plan study in order to develop a realistic and achievable blueprint for implementation of high speed rail in the Chicago-St. Louis corridor. This report presents a summary of the Price Waterhouse Project Team's analysis and the Financial and Implementation Plan for implementing high speed rail service in the Chicago-St. Louis corridor

Chicago-St. Louis high speed rail plan

Energy Technology Data Exchange (ETDEWEB)

Stead, M.E.

1994-12-31

The Illinois Department of Transportation (IDOT), in cooperation with Amtrak, undertook the Chicago-St. Louis High Speed Rail Financial and Implementation Plan study in order to develop a realistic and achievable blueprint for implementation of high speed rail in the Chicago-St. Louis corridor. This report presents a summary of the Price Waterhouse Project Team`s analysis and the Financial and Implementation Plan for implementing high speed rail service in the Chicago-St. Louis corridor.

Prevalence of Risk Factors for the Metabolic Syndrome in the Middle Income Caribbean Nation of St. Lucia

Directory of Open Access Journals (Sweden)

Colleen O’Brien Cherry

2014-01-01

Full Text Available The objective of this research was to measure the presence of metabolic syndrome risk factors in a sample population in the middle income Caribbean nation of St. Lucia and to identify the demographic and behavioral factors of metabolic syndrome among the study participants. Interviews and anthropometric measures were conducted with 499 St. Lucians of ages 18–99. Descriptive statistics were used for the analysis. Fifty-six percent of females and 18 percent of males had a waist size equal to or above the indicator for the metabolic syndrome. Behavioral risk factors such as sedentary lifestyle, smoking, and alcohol consumption varied by gender. Thirty-six percent of women and 22% of men reported a sedentary lifestyle and 43% of women and 65% of men reported any alcohol consumption. More research should be done to determine the cultural norms and gender differences associated with modifiable risk behaviors in St. Lucia.

Data Abstraction Mechanisms in Sina/st

NARCIS (Netherlands)

Meyrowitz, N.K.; Aksit, Mehmet; Tripathi, Anand

1988-01-01

This paper describes a new data abstraction mechanism in an object-oriented model of computing. The data abstraction mechanism described here has been devised in the context of the design of Sina/st language. In Sina/st no language constructs have been adopted for specifying inheritance or

Research and demonstration to improve air quality for the U.S. animal feeding operations in the 21st century – A critical review

International Nuclear Information System (INIS)

Ni, Ji-Qin

2015-01-01

There was an increasing interest in reducing production and emission of air pollutants to improve air quality for animal feeding operations (AFOs) in the U.S. in the 21st century. Research was focused on identification, quantification, characterization, and modeling of air pollutions; effects of emissions; and methodologies and technologies for scientific research and pollution control. Mitigation effects were on pre-excretion, pre-release, pre-emission, and post-emission. More emphasis was given on reducing pollutant emissions than improving indoor air quality. Research and demonstrations were generally continuation and improvement of previous efforts. Most demonstrated technologies were still in a limited scale of application. Future efforts are needed in many fundamental and applied research areas. Advancement in instrumentation, computer technology, and biological sciences and genetic engineering is critical to bring major changes in this area. Development in research and demonstration will depend on the actual political, economic, and environmental situations. - Highlights: • More emphasis was placed on pollutant emissions than indoor air quality. • Basic research dedicated to new pollutants, modeling, and baseline emissions. • Applied research focused on developing monitoring and mitigation technologies. • Field demonstrations combined with projects to evaluate new mitigation approaches. • Future efforts are needed in many fundamental and applied research areas. - Different scales of basic and applied research were conducted and 15 mitigation technologies were demonstrated. Future work is needed in many fundamental and applied research areas

Pretreatment with soluble ST2 reduces warm hepatic ischemia/reperfusion injury

International Nuclear Information System (INIS)

Yin Hui; Huang Baojun; Yang Heng; Huang Yafei; Xiong Ping; Zheng Fang; Chen Xiaoping; Chen Yifa; Gong Feili

2006-01-01

The interleukin-1 receptor-like protein ST2 exists in both membrane-bound (ST2L) and soluble form (sST2). ST2L has been found to play an important regulatory role in Th2-type immune response, but the function of soluble form of ST2 remains to be elucidated. In this study, we report the protective effect of soluble ST2 on warm hepatic ischemia/reperfusion injury. We constructed a eukaryotic expression plasmid, psST2-Fc, which expresses functional murine soluble ST2-human IgG1 Fc (sST2-Fc) fusion protein. The liver damage after ischemia/reperfusion was significantly attenuated by the expression of this plasmid in vivo. sST2-Fc remarkably inhibited the activation of Kupffer cells and the production of proinflammatory mediators TNF-α and IL-6. Furthermore, the levels of TLR4 mRNA and the nuclear translocation of NF-κB were also suppressed by pretreatment with sST2-Fc. These results thus identified soluble ST2 as a negative regulator in hepatic I/R injury, possibly via ST2-TLR4 pathway

United States Army Weapon Systems 2010

Science.gov (United States)

2009-09-18

equipment, tractor, van, wrecker, 8.8-ton Load Handling System (LHS), 8.8-ton LHS trailer, and 10-ton dump truck models). Three truck variants and...NJ) hydraulic pump and motor: Vickers (Jackson, MS) 131 UnIteD StAteS Army ACqUISItIon phASe InveStment Component High Mobility Engineer Excavator...MEDEVAC and hoist configuration, the UH-72A is also being fielded in a VIP, National Guard Homeland Security (HLS) and a Combined Training Center

ST segment/heart rate slope as a predictor of coronary artery disease: comparison with quantitative thallium imaging and conventional ST segment criteria

International Nuclear Information System (INIS)

Finkelhor, R.S.; Newhouse, K.E.; Vrobel, T.R.; Miron, S.D.; Bahler, R.C.

1986-01-01

The ST segment shift relative to exercise-induced increments in heart rate, the ST/heart rate slope (ST/HR slope), has been proposed as a more accurate ECG criterion for diagnosing significant coronary artery disease (CAD). Its clinical utility, with the use of a standard treadmill protocol, was compared with quantitative stress thallium (TI) and standard treadmill criteria in 64 unselected patients who underwent coronary angiography. The overall diagnostic accuracy of the ST/HR slope was an improvement over TI and conventional ST criteria (81%, 67%, and 69%). For patients failing to reach 85% of their age-predicted maximal heart rate, its diagnostic accuracy was comparable with TI (77% and 74%). Its sensitivity in patients without prior myocardial infarctions was equivalent to that of thallium (91% and 95%). The ST/HR slope was directly related to the angiographic severity (Gensini score) of CAD in patients without a prior infarction (r = 0.61, p less than 0.001). The ST/HR slope was an improved ECG criterion for diagnosing CAD and compared favorably with TI imaging

Three Good Reasons for Celebrating at the ESO/ST-ECF Science Archive Facility

Science.gov (United States)

2000-12-01

Great Demand for Data from New "Virtual Observatory" Summary Due to a happy coincidence, the ESO/ST-ECF Science Archive Facility is celebrating three different milestones at the same time: * its 10th anniversary since the establishment in 1991 * the 10,000th request for data , and * the signing-up of active user number 2000 . This Archive contains over 8 Terabytes (1 Terabyte = 1 million million bytes) of valuable observational data from the NASA/ESA Hubble Space Telescope (HST), the ESO Very Large Telescope (VLT) and other ESO telescopes . Its success paves the way for the establishment of "Virtual Observatories" from which first-class data can be obtained by astronomers all over the world. This greatly enhances the opportunities for more (young) scientists to participate in front-line research. PR Photo 34/00 : Front-page of a new brochure, describing the ESO/ST-ECF Science Archive Facility. Just 10 years ago, on the 1st of January 1991, the ESO/ST-ECF (European Southern Observatory/Space Telescope-European Coordinating Facility) Science Archive Facility opened. It has since served the astronomical community with gigabyte after gigabyte of high-quality astronomical data from some of the world's leading telescopes. The Archive, which is located in Garching, just outside Munich (Germany), contains data from the 2.4-m NASA/ESA Hubble Space Telescope , as well as from several ESO telescopes: the four 8.2-m Unit Telescopes of the Very Large Telescope (VLT) at the Paranal Observatory , and the 3.5-m New Technology Telescope (NTT) , the 3.6-m telescope and the MPG/ESO 2.2-m telescope at La Silla. The Archive is a continuously developing project - in terms of amounts of data stored, the number of users and in particular because of the current dramatic development of innovative techniques for data handling and storage. In the year 2000 more than 2 Terabytes (2000 Gigabytes) of data were distributed to users worldwide. The archiving of VLT data has been described in ESO PR

E-st@r-I experience: Valuable knowledge for improving the e-st@r-II design

Science.gov (United States)

Corpino, S.; Obiols-Rabasa, G.; Mozzillo, R.; Nichele, F.

2016-04-01

Many universities all over the world have now established hands-on education programs based on CubeSats. These small and cheap platforms are becoming more and more attractive also for other-than-educational missions, such as technology demonstration, science applications, and Earth observation. This new paradigm requires the development of adequate technology to increase CubeSat performance and mission reliability, because educationally-driven missions have often failed. In 2013 the ESA Education Office launched the Fly Your Satellite! Programme which aims at increasing CubeSat mission reliability through several actions: to improve design implementation, to define best practices for conducting the verification process, and to make the CubeSat community aware of the importance of verification. Within this framework, the CubeSat team at Politecnico di Torino developed the e-st@r-II CubeSat as follow-on of the e-st@r-I satellite, launched in 2012 on the VEGA Maiden Flight. E-st@r-I and e-st@r-II are both 1U satellites with educational and technology demonstration objectives: to give hands-on experience to university students and to test an active attitude determination and control system based on inertial and magnetic measurements with magnetic actuation. This paper describes the know-how gained thanks to the e-st@r-I mission, and how this heritage has been translated into the improvement of the new CubeSat in several areas and lifecycle phases. The CubeSat design has been reviewed to reduce the complexity of the assembly procedure and to deal with possible failures of the on-board computer, for example re-coding the software in the communications subsystem. New procedures have been designed and assessed for the verification campaign accordingly to ECSS rules and with the support of ESA specialists. Different operative modes have been implemented to handle some anomalies observed during the operations of the first satellite. A new version of the on-board software is

Developing Skills for Youth in the 21st Century: The Role of Elite International Baccalaureate Diploma Programme Schools in China

Science.gov (United States)

Wright, Ewan; Lee, Moosung

2014-01-01

There is a growing body of research suggesting that schools need to respond to changing social and economic dynamics by prioritising "21st-century skills". Proponents of this view, who have been termed "the 21st century skills movement", have called for greater emphasis on cognitive and non-cognitive skills development,…

The impacts of the St. Patrick's Day superstorm on selected technologies

Science.gov (United States)

Carter, B. A.; Yizengaw, E.; Lin, C. S.; Pradipta, R.; Norman, R.; Tseng, T.; Bennett, J.; Bishop, R. L.; Weygand, J. M.; Francis, M.; Terkildsen, M. B.; Groves, K. M.; Caton, R. G.; Tripathi, N.; Zhang, K.

2015-12-01

In the past, significant research efforts have been directed towards understanding how severe geomagnetic storms affect the near-Earth space environment. From this research, we have learned that many technologies are affected by these severe space weather events. The 2015 St. Patrick's Day geomagnetic storm has provided a great opportunity to analyze three selected space weather phenomena that adversely impact modern technologies; (1) Geomagnetically Induced Currents (GICs), (2) increased thermospheric mass density, and (3) the occurrence of Equatorial Plasma Bubbles (EPBs). The serious effects of GICs on power grids in the high-latitude regions is well known. Recent research has indicated that the equatorial region is also susceptible to increased GIC activity due to the equatorial electrojet. Thus, an examination of the equatorial magnetometer data during the St. Patrick's Day storm will be presented. It is also well understood that during geomagnetic storms, the thermospheric mass density at a given altitude increases due to the increase in Joule heating in the high-latitude regions. As a consequence of this, low-Earth orbiting satellites and space debris experience increased atmospheric drag. Changes in atmospheric drag causes orbits to be perturbed, resulting in less accurate orbit predictions. An investigation of the orbits of several low-Earth orbiting satellites will be presented and discussed in the context of collision avoidance, as part of the ongoing space debris problem. Finally, Equatorial Plasma Bubbles (EPBs) are a common phenomenon in the nighttime low-latitude ionosphere. EPBs are known to cause random fluctuations (i.e., scintillations) in the amplitude and phase of trans-ionospheric radio signals. While EPBs have been reported during both geomagnetically quiet and disturbed periods, research clearly indicates that the occurrence of EPBs is dependent on the geomagnetic activity level. The occurrence of EPBs around the world will be presented

The status of beryllium research for fusion in the United States

International Nuclear Information System (INIS)

Longhurst, G.R.; Snead, L.L.; Abou-Sena, A.A.

2004-01-01

Use of beryllium in fusion reactor has been considered for neutron multiplication in breeding blankets an as an oxygen getter for plasma - facing surface. Previous beryllium research for fusion in the United States included issues of interest to fission (swelling an changes in mechanical and thermal properties) as well as interactions with plasmas and hydrogen isotopes and methods of fabrication. When the United States formally withdrew its participation in the International Experimental Reactor (ITER) program, much of this effort was terminated. The focus in the U.S. has been mainly on toxic effects of beryllium and on industrial hygiene and health-related issues. Work continued at the INEEL (Idaho National Engineering and Environmental Laboratory) and elsewhere on beryllium-containing molten salts. This activity is part of the JUPITER II Agreement. Plasma spray of ITER first wall samples at Los Alamos National Laboratory has been performed under the European Fusion Development Agreement. Effects of irradiation on beryllium structure are being studied at Oak Ridge National Laboratory. Numerical and phenomenological models are being developed and applied at the University of California Los Angels to investigate thermo-mechanical characteristics of beryllium pebble beds, similar to research being carried out at Forschungszentrum Karlsruhe and elsewhere. Additional work, not funded by the fusion program, has dealt with issues of disposal, and recycling. (author)

The Status of Beryllium Research for Fusion in the United States

International Nuclear Information System (INIS)

Glen R. Longhurst

2003-01-01

Use of beryllium in fusion reactors has been considered for neutron multiplication in breeding blankets and as an oxygen getter for plasma-facing surfaces. Previous beryllium research for fusion in the United States included issues of interest to fission (swelling and changes in mechanical and thermal properties) as well as interactions with plasmas and hydrogen isotopes and methods of fabrication. When the United States formally withdrew its participation in the International Thermonuclear Experimental Reactor (ITER) program, much of this effort was terminated. The focus in the U.S. has been mainly on toxic effects of beryllium and on industrial hygiene and health-related issues. Work continued at the INEEL and elsewhere on beryllium-containing molten salts. This activity is part of the JUPITER II Agreement. Plasma spray of ITER first wall samples at Los Alamos National Laboratory has been performed under the European Fusion Development Agreement. Effects of irradiation on beryllium structure are being studied at Oak Ridge National Laboratory. Numerical and phenomenological models are being developed and applied to better understand important processes and to assist with design. Presently, studies are underway at the University of California Los Angeles to investigate thermo-mechanical characteristics of beryllium pebble beds, similar to research being carried out at Forschungszentrum Karlsruhe and elsewhere. Additional work, not funded by the fusion program, has dealt with issues of disposal, and recycling

IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy.

Science.gov (United States)

Liu, Boyi; Tai, Yan; Achanta, Satyanarayana; Kaelberer, Melanie M; Caceres, Ana I; Shao, Xiaomei; Fang, Jianqiao; Jordt, Sven-Eric

2016-11-22

Poison ivy-induced allergic contact dermatitis (ACD) is the most common environmental allergic condition in the United States. Case numbers of poison ivy ACD are increasing due to growing biomass and geographical expansion of poison ivy and increasing content of the allergen, urushiol, likely attributable to rising atmospheric CO 2 Severe and treatment-resistant itch is the major complaint of affected patients. However, because of limited clinical data and poorly characterized models, the pruritic mechanisms in poison ivy ACD remain unknown. Here, we aim to identify the mechanisms of itch in a mouse model of poison ivy ACD by transcriptomics, neuronal imaging, and behavioral analysis. Using transcriptome microarray analysis, we identified IL-33 as a key cytokine up-regulated in the inflamed skin of urushiol-challenged mice. We further found that the IL-33 receptor, ST2, is expressed in small to medium-sized dorsal root ganglion (DRG) neurons, including neurons that innervate the skin. IL-33 induces Ca 2+ influx into a subset of DRG neurons through neuronal ST2. Neutralizing antibodies against IL-33 or ST2 reduced scratching behavior and skin inflammation in urushiol-challenged mice. Injection of IL-33 into urushiol-challenged skin rapidly exacerbated itch-related scratching via ST2, in a histamine-independent manner. Targeted silencing of neuronal ST2 expression by intrathecal ST2 siRNA delivery significantly attenuated pruritic responses caused by urushiol-induced ACD. These results indicate that IL-33/ST2 signaling is functionally present in primary sensory neurons and contributes to pruritus in poison ivy ACD. Blocking IL-33/ST2 signaling may represent a therapeutic approach to ameliorate itch and skin inflammation related to poison ivy ACD.

The health protection of riparian populations in case of a major oil spill:. The St. Lawrence Vision 2000 Shores project

International Nuclear Information System (INIS)

Guerrier, P.; Tardif, G.

1995-01-01

Objectives of a research project to protect the health of riparian populations in the event of a major oil spill in the St. Lawrence river were summarized. The project is a part of the health component of the St. Lawrence Vision 2000 (SLV-2000) action plan, which is a product of co-operation among Environment Canada, Health Canada, le ministere de la Sante et des Services sociaux du Quebec, and other government departments, designed to protect and conserve the St. Lawrence river and its environment

Progress of the United States foreign research reactor spent nuclear fuel acceptance program

International Nuclear Information System (INIS)

Huizenga, D.G.; Clapper, M.; Thrower, A.W.

2002-01-01

The United States Department of Energy (DOE), in consultation with the Department of State (DOS), adopted the Nuclear Weapons Nonproliferation Policy Concerning Foreign Research Reactor Spent Nuclear Fuel in May 1996. To date, the Foreign Research Reactor (FRR) Spent Nuclear Fuel (SNF) Acceptance Program has completed 23 shipments. Almost 5000 spent fuel assemblies from eligible research reactors throughout the world have been accepted into the United States under this program. Over the past year, another cross-country shipment of fuel was accomplished, as well as two additional shipments in the fourth quarter of calendar year 2001. These shipments attracted considerable safeguards oversight since they occurred post September 11. Recent guidance from the Nuclear Regulatory Commission (NRC) pertaining to security and safeguards issues deals directly with the transport of nuclear material. Since the Acceptance Program has consistently applied above regulatory safety enhancements in transport of spent nuclear fuel, this guidance did not adversely effect the Program. As the Program draws closer to its termination date, an increased number of requests for program extension are received. Currently, there are no plans to extend the policy beyond its current expiration date; therefore, eligible reactor operators interested in participating in this program are strongly encouraged to evaluate their inventory and plan for future shipments as soon as possible. (author)

Electrocardiogram ST-Segment Morphology Delineation Method Using Orthogonal Transformations.

Directory of Open Access Journals (Sweden)

Miha Amon

Full Text Available Differentiation between ischaemic and non-ischaemic transient ST segment events of long term ambulatory electrocardiograms is a persisting weakness in present ischaemia detection systems. Traditional ST segment level measuring is not a sufficiently precise technique due to the single point of measurement and severe noise which is often present. We developed a robust noise resistant orthogonal-transformation based delineation method, which allows tracing the shape of transient ST segment morphology changes from the entire ST segment in terms of diagnostic and morphologic feature-vector time series, and also allows further analysis. For these purposes, we developed a new Legendre Polynomials based Transformation (LPT of ST segment. Its basis functions have similar shapes to typical transient changes of ST segment morphology categories during myocardial ischaemia (level, slope and scooping, thus providing direct insight into the types of time domain morphology changes through the LPT feature-vector space. We also generated new Karhunen and Lo ève Transformation (KLT ST segment basis functions using a robust covariance matrix constructed from the ST segment pattern vectors derived from the Long Term ST Database (LTST DB. As for the delineation of significant transient ischaemic and non-ischaemic ST segment episodes, we present a study on the representation of transient ST segment morphology categories, and an evaluation study on the classification power of the KLT- and LPT-based feature vectors to classify between ischaemic and non-ischaemic ST segment episodes of the LTST DB. Classification accuracy using the KLT and LPT feature vectors was 90% and 82%, respectively, when using the k-Nearest Neighbors (k = 3 classifier and 10-fold cross-validation. New sets of feature-vector time series for both transformations were derived for the records of the LTST DB which is freely available on the PhysioNet website and were contributed to the LTST DB. The

Competences for science teaching at the 21st century

OpenAIRE

Sá, Patrícia; Paixão, Fátima

2016-01-01

This study presents a contribution to the conceptual and terminological clarification of the concept of teaching competence, as well as for the identification of a competencial framework of competences for science teaching at a primary education level, having in mind educating citizens for the 21st century as scientific literates. The proposed framework was developed based on an intensive literature review and on the contributions emerging from a shared reflection between researchers in scien...

NASA-UVA Light Aerospace Alloy and Structures Technology Program (LA2ST)

Science.gov (United States)

Gangloff, Richard P.; Scully, John R.; Stoner, Glenn E.; Thornton, Earl A.; Wawner, Franklin E., Jr.; Wert, John A.

1993-01-01

The NASA-UVA Light Aerospace Alloy and Structures Technology (LA2ST) Program continues a high level of activity. Progress achieved between 1 Jan. and 30 Jun. 1993 is reported. The objective of the LA2ST Program is to conduct interdisciplinary graduate student research on the performance of next generation, light weight aerospace alloys, composites, and thermal gradient structures in collaboration with NASA-Langley researchers. The following projects are addressed: environmental fatigue of Al-Li-Cu alloys; mechanisms of localized corrosion and environmental fracture in Al-Cu-Li-Mg-Ag alloy X2095 and compositional variations; the effect of zinc additions on the precipitation and stress corrosion cracking behavior of alloy 8090; hydrogen interactions with Al-Li-Cu alloy 2090 and model alloys; metastable pitting of aluminum alloys; cryogenic fracture toughness of Al-Cu-Li + In alloys; the fracture toughness of Weldalite (TM); elevated temperature cracking of advanced I/M aluminum alloys; response of Ti-1100/SCS-6 composites to thermal exposure; superplastic forming of Weldalite (TM); research to incorporate environmental effects into fracture mechanics fatigue life prediction codes such as NASA FLAGRO; and thermoviscoplastic behavior.

Virulence of invasive Salmonella Typhimurium ST313 in animal models of infection.

Directory of Open Access Journals (Sweden)

Girish Ramachandran

2017-08-01

Full Text Available Salmonella Typhimurium sequence type (ST 313 produces septicemia in infants in sub-Saharan Africa. Although there are known genetic and phenotypic differences between ST313 strains and gastroenteritis-associated ST19 strains, conflicting data about the in vivo virulence of ST313 strains have been reported. To resolve these differences, we tested clinical Salmonella Typhimurium ST313 and ST19 strains in murine and rhesus macaque infection models. The 50% lethal dose (LD50 was determined for three Salmonella Typhimurium ST19 and ST313 strains in mice. For dissemination studies, bacterial burden in organs was determined at various time-points post-challenge. Indian rhesus macaques were infected with one ST19 and one ST313 strain. Animals were monitored for clinical signs and bacterial burden and pathology were determined. The LD50 values for ST19 and ST313 infected mice were not significantly different. However, ST313-infected BALB/c mice had significantly higher bacterial numbers in blood at 24 h than ST19-infected mice. ST19-infected rhesus macaques exhibited moderate-to-severe diarrhea while ST313-infected monkeys showed no-to-mild diarrhea. ST19-infected monkeys had higher bacterial burden and increased inflammation in tissues. Our data suggest that Salmonella Typhimurium ST313 invasiveness may be investigated using mice. The non-human primate results are consistent with clinical data, suggesting that ST313 strains do not cause diarrhea.

Virulence of invasive Salmonella Typhimurium ST313 in animal models of infection.

Science.gov (United States)

Ramachandran, Girish; Panda, Aruna; Higginson, Ellen E; Ateh, Eugene; Lipsky, Michael M; Sen, Sunil; Matson, Courtney A; Permala-Booth, Jasnehta; DeTolla, Louis J; Tennant, Sharon M